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Sample records for amplatzer vascular plug

  1. Bilateral transrenal ureteral occlusion by means of n-butyl cyanoacrylate and AMPLATZER vascular plug

    OpenAIRE

    Grasso, Rosario F; Roberto Luigi Cazzato; Giacomo Luppi; Simona Mercurio; Francesco Giurazza; Riccardo Del Vescovo; Eliodoro Faiella; Bruno Beomonte Zobel

    2014-01-01

    AMPLATZER vascular plug is a widely used embolic agent. In the present paper, we present a case of an 86-year-old female patient who underwent bilateral ureteral occlusion by means of AMPLATZER vascular plug II coupled to n-butyl cyanoacrylate (NBCA) because of recurring pyelonephritis following cystectomy with subsequent bilateral ureterosigmoidostomy (sec. Mainz type II).

  2. Bilateral transrenal ureteral occlusion by means of n-butyl cyanoacrylate and AMPLATZER vascular plug

    Directory of Open Access Journals (Sweden)

    Rosario F Grasso

    2014-01-01

    Full Text Available AMPLATZER vascular plug is a widely used embolic agent. In the present paper, we present a case of an 86-year-old female patient who underwent bilateral ureteral occlusion by means of AMPLATZER vascular plug II coupled to n-butyl cyanoacrylate (NBCA because of recurring pyelonephritis following cystectomy with subsequent bilateral ureterosigmoidostomy (sec. Mainz type II.

  3. Amplatzer vascular plug as an embolic agent in different vascular pathologies: A pictorial essay

    Science.gov (United States)

    Tresley, Jonathan; Bhatia, Shivank; Kably, Issam; Poozhikunnath Mohan, Prasoon; Salsamendi, Jason; Narayanan, Govindarajan

    2016-01-01

    The Amplatzer Vascular Plug (AVP) is a cylindrical plug made of self-expanding nitinol wire mesh with precise delivery control, which can be used for a variety of vascular pathologies. An AVP is an ideal vascular occlusion device particularly in high-flow vessels, where there is high risk of migration and systemic embolization with traditional occlusion devices. We performed 28 embolizations using the AVP from 2009 to 2014 and achieved complete occlusion without complications.

  4. Transcatheter closure of small ductus arteriosus with amplatzer vascular plug

    Directory of Open Access Journals (Sweden)

    Eunhyun Cho

    2013-09-01

    Full Text Available Purpose: The purpose of this study was to share our experience of transcatheter closure of small patent ductus arteriosus (PDA by using an Amplatzer vascular plug (AVP.<br> Methods: We reviewed the medical records of 20 patients who underwent transcatheter closure at Samsung Medical Center and Sejong General Hospital from January 2008 to August 2012. The size and shape of the PDAs were evaluated by performing angiograms, and the PDA size and the AVP devices size were compared.<br>Results: The mean age of the patients was 54.9±45.7 months old. The PDAs were of type C (n=5, type D (n=12 and type E (n=3. The mean pulmonary end diameter of the PDA was 1.7±0.6 mm, and the aortic end diameter was 3.6±1.4 mm. The mean length was 7.3±1.8 mm. We used 3 types of AVP devices: AVP I (n=5, AVP II (n=7, and AVP IV (n=8. The ratio of AVP size to the pulmonary end diameter was 3.37±1.64, and AVP size/aortic end ratio was 1.72±0.97. The aortic end diameter was significantly larger in those cases repaired with AVP II than in the others (P =0.002. The AVP size did not significantly correlate with the PDA size, but did correlate with smaller ratio of AVP size to aortic end diameter (1.10±0.31, P =0.032. <br>Conclusion: Transcatheter closure of small PDA with AVP devices yielded satisfactory outcome. AVP II was equally effective with smaller size of device, compared to others.

  5. Advantages and Disadvantages of the Amplatzer Vascular Plug IV in Visceral Embolization: Report of 50 Placements

    International Nuclear Information System (INIS)

    Purpose: We describe our initial clinical experience in artificial embolization with the Amplatzer Vascular Plug IV (VP IV), a further development of the Vascular Plug family already in routine use. Methods: Results from 50 embolization procedures conducted with the VP IV in 44 patients are summarized. Results: All 50 embolizations were successful, although two required the technique to be modified because of problems with jamming of the screw thread and thus with disconnection of the plug. This was associated with large branching angles. Conclusions: With experience, the VP IV can be used safely and effectively, and it expands the spectrum of possible embolizations in interventional radiology. Its greatest disadvantage is its relatively poor positional controllability.

  6. Transhepatic Preoperative Portal Vein Embolization Using the Amplatzer Vascular Plug: Report of Four Cases

    International Nuclear Information System (INIS)

    The Amplatzer Vascular Plug (AVP) is a device originally intended for arterial and venous embolization in peripheral vessels. From December 2004 to March 2007 we implanted a total of 8 AVPs in the portal venous system in our institution for preoperative portal vein embolization in 4 patients (55-71 years) prior to right hemihepatectomy. AVP implantation was successful in all patients. Total occlusion of the embolized portal vein branches was achieved in all patients. There were no major complications associated with the embolization

  7. Amplatzer vascular plug IV for occlusion of pulmonary arteriovenous malformations in a patient with cryptogenic stroke

    Directory of Open Access Journals (Sweden)

    Surendranath R Veeram Reddy

    2014-01-01

    Full Text Available Paradoxical embolism resulting in cryptogenic stroke has received much attention recently, with the primary focus on patent foramen ovale (PFO. However, it is essential to be vigilant in the search for other causes of paradoxical embolic events, such as pulmonary arteriovenous malformations (PAVM. We describe successful closure of pulmonary AVM with a St Jude Medical (Plymouth, MN Amplatzer TM vascular plug IV. The newer AVP-IV devices can be used for successful embolization of tortuous pulmonary AVM in remote locations where use of other traditional devices may be technically challenging.

  8. [Amplatzer® Vascular Plug III, for closing residual mitral paravalvular leak: three-dimensional transesophageal echocardiography image].

    Science.gov (United States)

    Reyes-Gómez, Carlos Alberto; García-Montes, José Antonio; Arias-Godínez, Antonio; Zabal-Cerdeira, Carlos

    2015-01-01

    Paravalvular leak is a significant complication after surgical valve replacement. Traditionally, redo surgery has been considered the treatment of choice, but is associated with high morbidity and mortality as well as increase risk of developing new leaks. Percutaneous treatment of paravalvular leak appears as an attractive alternative. Such treatment has been made possible by the current ability to integrate multiple imaging modalities that have helped to define the anatomy of the defect and planning and guiding the percutaneous closure procedure, thus resulting in better outcomes. The Amplatzer® Vascular Plug III (St. Jude Medical) is the first device specifically designed for percutaneous closure of paravalvular leak with promising results. We present the three-dimensional transesophageal echocardiographic images of a successful outcome of percutaneous closure of a residual mitral paravalvular leak with an Amplatzer® Vascular Plug III device (St. Jude Medical), after an initial procedure of percutaneous closure with an Amplatzer® duct occluder (St. Jude Medical). PMID:25912709

  9. Endovascular treatment of a ruptured pulmonary artery aneurysm in a patient with Behcet's disease using the amplatzer vascular plug 4

    International Nuclear Information System (INIS)

    A pulmonary artery aneurysm is a common manifestation and the leading cause of mortality in Behcet's disease. We describe a case of spontaneous rupture of a pulmonary artery aneurysm that, due to the inadequacy of medical therapy and the disadvantages of surgery, became the ideal candidate for endovascular management and was successfully performed by using the Amplatzer Vascular Plug 4.

  10. Percutaneous Transcatheter Embolization of a Large Pulmonary Arteriovenous Fistula with an Amplatzer Vascular Plug

    International Nuclear Information System (INIS)

    Percutaneous transcatheter embolization has become the treatment of choice for pulmonary arteriovenous fistulas (PAVFs), in most cases replacing surgical intervention. However, while 'classic' devices, such as intravascular coils and detachable balloons, have proved to be successful for interventional occlusions of small or medium-sized PAVFs, they are not ideal in larger fistulas because of the risk for embolization to the systemic circulation. We describe the case of a 61-year-old woman with a symptomatic huge solitary pulmonary arteriovenous fistula (4.5 cm in diameter), occupying part of the lung in the lower right lobe with two feeding arteries (10 and 4 mm in diameter, respectively), who underwent successful transcatheter closure with an Amplatzer Vascular Plug, a new device designed for the occlusion of vascular abnormalities

  11. Ureteric Embolization for Lower Urinary Tract Fistulae: Use of Two Amplatzer Vascular Plugs and N-Butyl Cyanoacrylate Employing the 'Sandwich' Technique

    Energy Technology Data Exchange (ETDEWEB)

    Saad, Wael E. A., E-mail: ws6r@virginia.edu; Kalagher, S.; Turba, U. C.; Sabri, S. S.; Park, A.-W.; Stone, J.; Angle, J. F.; Matsumoto, A. H. [University of Virginia Health System, Department of Radiology and Medical Imaging, Division of Vascular Interventional Radiology (United States)

    2013-08-01

    PurposeThis study describes and evaluated the effectiveness of occluding distal ureters in the clinical setting of urinary vaginal (vesicovaginal or enterovesicovaginal) fistulae utilizing a new technique which combines Amplatzer vascular plugs and N-butyl cyanoacrylate.MaterialsThis is a retrospective study (January 2007-December 2010) of patients with urinary-vaginal fistulae undergoing distal ureter embolization utilizing an Amplatzer- N-butyl cyanoacrylate-Amplatzer sandwich technique. An 8-12-mm type-I or type-II Amplatzer vascular plug was delivered using the sheath and deployed in the ureter distal to the pelvic brim. Instillation of 0.8-1.5 cc of N-butyl cyanoacrylate into ureter proximal to the Amplatzer plug was performed. This was followed by another set of 8-12-mm type-I or type-II Amplatzer vascular plugs in a technique referred to as the 'sandwich technique.'ResultsFive ureters in three patients were occluded utilizing the above-described technique during the 4-year study period. Mean maximum size Amplatzer used per ureter was 10.8 mm (range, 8-12). One ureter required three Amplatzer plugs and the rest required two. Two patients (3 ureters) were clinically successful with complete resolution of symptoms in 36-48 h. The third patient (2 ureters) was partly successful and required a second Amplatzer- N-butyl cyanoacrylate sandwich technique embolization. The mean clinical follow-up was 11.3 months (range, 1.7-29.2).ConclusionsThe Amplatzer- N-butyl cyanoacrylate-Amplatzer sandwich technique for occluding the distal ureter is safe and effective with a quick (probably due to the N-butyl cyanoacrylate) and durable (probably due to the Amplatzer plugs) clinical response.

  12. Ureteric Embolization for Lower Urinary Tract Fistulae: Use of Two Amplatzer Vascular Plugs and N-Butyl Cyanoacrylate Employing the “Sandwich” Technique

    International Nuclear Information System (INIS)

    PurposeThis study describes and evaluated the effectiveness of occluding distal ureters in the clinical setting of urinary vaginal (vesicovaginal or enterovesicovaginal) fistulae utilizing a new technique which combines Amplatzer vascular plugs and N-butyl cyanoacrylate.MaterialsThis is a retrospective study (January 2007–December 2010) of patients with urinary-vaginal fistulae undergoing distal ureter embolization utilizing an Amplatzer- N-butyl cyanoacrylate-Amplatzer sandwich technique. An 8–12–mm type-I or type-II Amplatzer vascular plug was delivered using the sheath and deployed in the ureter distal to the pelvic brim. Instillation of 0.8–1.5 cc of N-butyl cyanoacrylate into ureter proximal to the Amplatzer plug was performed. This was followed by another set of 8–12-mm type-I or type-II Amplatzer vascular plugs in a technique referred to as the “sandwich technique.”ResultsFive ureters in three patients were occluded utilizing the above-described technique during the 4-year study period. Mean maximum size Amplatzer used per ureter was 10.8 mm (range, 8–12). One ureter required three Amplatzer plugs and the rest required two. Two patients (3 ureters) were clinically successful with complete resolution of symptoms in 36–48 h. The third patient (2 ureters) was partly successful and required a second Amplatzer- N-butyl cyanoacrylate sandwich technique embolization. The mean clinical follow-up was 11.3 months (range, 1.7–29.2).ConclusionsThe Amplatzer- N-butyl cyanoacrylate-Amplatzer sandwich technique for occluding the distal ureter is safe and effective with a quick (probably due to the N-butyl cyanoacrylate) and durable (probably due to the Amplatzer plugs) clinical response

  13. Splenic Artery Syndrome After Orthotopic Liver Transplantation: Treatment With the Amplatzer Vascular Plug

    International Nuclear Information System (INIS)

    Purpose: To evaluate the safety and efficacy of the Amplatzer vascular plug (AVP) for embolization of the splenic artery in patients with hepatic hypoperfusion after orthotopic liver transplantation (OLT). Materials and Methods: Thirteen patients (9 men and 4 women) with a mean age of 56 years (range 22–70) who developed splenic artery syndrome after OLT with decreased liver perfusion and clinically relevant impairment of liver function (increased transaminase or serum bilirubin levels, thrombocytopenia, and/or therapy-refractory ascites) were treated by embolization of the proximal third of the splenic artery using the AVP. The plugs ranged in diameter from 6 to 16 mm, and they were introduced through femoral (n = 9), axillary (n = 3), or brachial (n = 1) access using a 5F or 8F guiding catheter. Results: The plugs were successfully placed, and complete occlusion of the splenic artery was achieved in all patients. Placement of two plugs was necessary for complete occlusion in 3 of the 13 patients. Occlusion took on average 10 min (range 4–35). There was no nontarget embolization or plug migration into more distal segments of the splenic artery. All patients showed improved arterial perfusion, including the liver periphery, on postinterventional angiogram. After embolization, liver function parameters (transaminase and bilirubin levels) improved with normalization of concomitant thrombocytopenia and a decrease in ascites volume. Conclusion: Our initial experience in a small patient population with SAS suggests that the AVP enables precise embolization of the proximal splenic artery, thus providing safe and effective treatment for poor liver perfusion after OLT due to SAS.

  14. Renal Artery Stump to Inferior Vena Cava Fistula: Unusual Clinical Presentation and Transcatheter Embolization with the Amplatzer Vascular Plug

    International Nuclear Information System (INIS)

    Fistulous communication between the renal artery stump and inferior vena cava following nephrectomy is rare. We describe the case of a 52-year-old man with a fistula detected on investigation for hemolytic anemia in the postoperative period. The patient had had a nephrectomy performed 2 weeks prior to presentation for blunt abdominal trauma. The fistula was successfully occluded percutaneously using an Amplatzer vascular plug. The patient recovered completely and was discharged 2 weeks later.

  15. The Amplatzer Vascular Plug: A Review of the Device and its Clinical Applications

    International Nuclear Information System (INIS)

    The Amplatzer Vascular Plug (AVP) is an established embolic device that can be an excellent alternative to coils or detachable balloons to embolize medium to large vessels with high flow. The device is easy to use and can be precisely deployed in the target vessel with high resistance to migration and a low recanalization rate. The technical success of this device is high, indications for use are expanding, and no absolute contraindications have been reported. Since its introduction, the AVP has grown from a single device to a group of 4 models (AVP, AVP II, AVP III, and AVP 4). Each model has a unique design and features that fit different vascular anatomies, hemodynamic situations, and clinical scenarios. Therefore, the new models cannot simply be treated as replacements for older ones. Unpredictable occlusion time remains a major shortcoming for the new models of the AVP. Large vessel size, high flow status, and coagulopathy can prolong the occlusion time, which can offset the cost benefit, reduced procedure time, and reduced radiation dose typically seen with use of the AVP alone. Coils or multiple AVPs can be used to expedite the occlusion process, and large Gelfoam particles also can be used as an adjunct to achieve rapid and reliable occlusion with minimal cost.

  16. Application of the AMPLATZER Vascular Plug in Endovascular Occlusion of Dialysis Accesses

    International Nuclear Information System (INIS)

    The purpose of this study was to share our initial experience with the AMPLATZER Vascular Plug (AVP) in occluding dialysis accesses. Between January 2007 and October 2008, five patients with autogenous and one patient with prosthetic accesses were referred for endovascular occlusion owing to central venous obstruction (n = 4) and dialysis-associated steal syndrome (n = 2) leading to disabling complications. We used a single AVP in two patients, double AVPs in two patients, and double AVPs and n-butyl 2-cyanoacrylate in one patient with an autogenous access. Two coils were deployed between two AVPs to occlude the prosthetic graft. Immediate success was achieved in all patients, with no complications. Mean follow-up time was 13 months (range, 1-21 months) and none of the patients had experienced symptom recurrence as of the time of writing. The AVP allows simple, precise, and reliable dialysis access occlusion without significant complications when surgical ligation is not preferred. It can be used with other embolizing agents to provide occlusion in the case of failure.

  17. Transesophageal echocardiographic guidance for percutaneous closure of aortic pseudoaneurysm using a type II Amplatzer vascular plug: a case report

    Science.gov (United States)

    Lee, Sangmin Maria; Sung, Kiick; Kang, I-Seok; Min, Jeong Jin; Kim, Eunhee; Park, Jiyeon; Park, Jin Hyoung

    2016-01-01

    Aortic pseudoaneurysm after cardiac surgery is a rare entity, but it is potentially fatal due to its clinical course along with higher morbidity and mortality rates. Instead of open surgical repair, percutaneous procedures have been introduced as other options for managing an aortic pseudoaneurysm. In this case report, we describe transesophageal echocardiography guidance for successful percutaneous closure of an aortic pseudoaneurysm located in the left ventricular outflow tract by using a type II Amplatzer vascular plug in a patient in whom open surgical repair was not recommended. PMID:27482320

  18. Cierre de fístula coronaria con Amplatzer vascular plug en el paciente pediátrico

    OpenAIRE

    Ricardo Gamboa; Francisco P. Mollón; Ríos Méndez,Raúl E; Gutiérrez,Diego F

    2008-01-01

    La fístula coronaria congénita es una patología poco frecuente y en general asintomática, por lo que muchas veces se diagnostica por un hallazgo incidental. Con dependencia de la repercusión hemodinámica, algunos siguen una conducta conservadora, otros indican tratamiento quirúrgico o, más recientemente, oclusión por cateterismo.Se presenta el caso de una paciente con una gran fístula coronaria-cameral, que se trató mediante embolización percutánea con dispositivo Amplatzer vascular plug. No ...

  19. Early Experience with the Amplatzer Vascular Plug II for Occlusive Purposes in Arteriovenous Hemodialysis Access

    International Nuclear Information System (INIS)

    The Amplatzer Vascular Plug Type II (AVP II) has proven effective in the therapeutic embolization of various vascular lesions. It benefits from very rapid occlusion of the target lesion and can be deployed, retrieved, and redeployed if required. There is no literature available on use of the AVP II in the maintenance, closure, and management of complicated arteriovenous access in hemodialysis patients. In this series, we present our clinical experience with the use of the AVP II for embolization of problematic hemodialysis access. The AVP II is a self-expandable Nitinol wire-mesh device. Mounted on a delivery wire it has the capability to be deployed, recaptured, and redeployed. In total seven patients (four males: one diabetic, all nonsmokers), with ages ranging from 44 to 81 years (mean, 63 years), were treated between July 2008 and January 2009. One patient had not started dialysis. The remaining six patients had varied histories, with the time on hemodialysis ranging from 1 to 21 years. Retrospective review of clinical notes revealed patient demographics, type of access, device size, deployment site, and outcomes. Indications for embolization included steal syndrome (one patient), high-flow tributaries (two patients), and limb swelling (four patients). All patients had clinical and sonographical follow-up to 3 months. Surgical ligation had either failed, was considered a contraindication due to concerns regarding wound healing, or was considered difficult due to complex venous anatomy. Only one device was used in each patient, ranging from 6 to 16 mm in diameter. Immediate technical success was seen in 100%. All these patients were followed up clinically in the vascular access radiology clinic at 4 weeks and 3 months. Occlusion of the treated vessel and resolution of symptoms were reconfirmed in 100% of cases at 3 months. It was also noted whether patients were having successful dialysis, if required. There were no complications. Average procedural time was 19

  20. Initial experience of occluding special type patent ductus arterioses using the Amplatzer vascular plug

    Institute of Scientific and Technical Information of China (English)

    ZHANG Po; ZHU Xian-yang; WANG Qi-guang; ZHANG Duan-zhen; HAN Xiu-min

    2013-01-01

    Background Occluders licensed for clinical use are not fit for some special Krichenko E patent ductus arterioses.The Amplatzer vascular plug I (AVP1) has not been licensed for use for closure of patent ductus arteriose.We report our initial experience to occluding special type patent ductus arterioses with the AVP1-a single lobe device of single layer Nitinol mesh for short vessel landing zones.Methods Patients referred with small and long Krichenko E patent ductus arterioses 1 mm to 3 mm in diameter underwent occlusion using AVP1.All cases underwent pre-,intra-and post-procedural echocardiography and chest X-ray at the completion of the procedure,the next day and at a 30-day,3-month and 6-month follow-up visits.Device sizing for device waist diameter and length was based on aortography.Results From April 2008 to June 2012,26 patients with a mean age of (7.6±8.0) years (range 6 months-32 years)and a mean weight of (23.8±14.8) kg (range 7-67 kg) underwent successful patent ductus arteriose closure.The mean ductus diameter was (2.1±0.7) mm (range 1-3 mm).Transpulmonary (22/26) and transaortic approaches (4/26) were used.No persistent patency was observed after 24 hours and after one month.No device displacement,residual flow and iatrogenic coarctation of the aorta were observed after three months and six months.Conclusions The AVP1 makes it easy to close some Krichenko E patent ductus arterioses.Smaller delivery catheter profile and symmetric cylindrical device shape allow for use for small and long Krichenko E patent ductus arterioses 1 mm to 3 mm in diameter and small patients through transaortic approaches.Broader experience is required to further delineate device and patient selection as well as to document its long-term efficacy and safety.

  1. Aneurysm of an Anomalous Systemic Artery Supplying the Normal Basal Segments of the Left Lower Lobe: Endovascular Treatment with the Amplatzer Vascular Plug II and Coils

    International Nuclear Information System (INIS)

    An anomalous systemic artery originating from the descending thoracic aorta supplying the normal basal segments of the lower lobe of the left lung without sequestration is a rare congenital anomaly. The published surgical treatments include lobectomy, segmentectomy, anastomosis, and ligation. In addition, endovascular treatment with coils has been reported. A second-generation occluder, the Amplatzer Vascular Plug II (AVP II), has a central plug and two occlusion disks and a finer, more densely woven nitinol wire, thus enabling faster embolization. This published case is the first successful occlusion of an aneurysm of an anomalous systemic artery with the AVP II and fibered coils, with 10 months of follow-up.

  2. Treatment of a Common Iliac Aneurysm by Endovascular Exclusion Using the Amplatzer Vascular Plug and Femorofemoral Crossover Graft

    International Nuclear Information System (INIS)

    We report our initial experience using the Amplatzer Vascular Plug II (AVP2) in the treatment of a left common iliac aneurysm. Following investigation by computerized tomographic angiography and catheter angiography, a 79-year-old man was found to have a markedly tortuous iliac system, with a left common iliac artery aneurysm that measured 48 mm in maximal diameter. Due to the patient's age and comorbidities the surgical opinion was that conventional open repair was not suitable. However, due to the tortuous nature of the aneurysm and iliac vessels, standard endovascular repair, using either a bifurcated or an aorto-uni-iliac stent graft, was also not possible. A combined approach was used by embolizing the ipsilateral internal iliac artery using coils and excluding the aneurysm using two AVP2 occlusion devices, followed by femorofemoral crossover grafting. Total aneurysm occlusion was achieved using this method and this allowed the patient to have a much less invasive surgical procedure than with conventional open repair of common iliac aneurysms, thus avoiding potential comorbidity and mortality.

  3. Percutaneous closure of a coronary fistula with single Amplatzer Vascular Plug II in a five-month-old female: The youngest case report.

    Science.gov (United States)

    Gulgun, Mustafa; Slack, Michael

    2016-02-01

    Coronary artery fistula (CAF) is a rare clinical abnormality characterized by a connection between one or more coronary arteries and an adjacent cardiac chamber or vascular structure. Although CAF complications are more common in older children over time, there is still no consensus in terms of treatment indications in children with asymptomatic fistula. We describe an asymptomatic infant diagnosed with a severely dilated right coronary artery and a coronary-cameral fistula treated successfully by transcatheter device closure. The Amplatzer Vascular Plug II appears to be safe, effective and relatively easy to use for CAF closure in infants. PMID:26852309

  4. Percutaneous Treatment of a Jejunovaginal Fistula Using a Combination of the Amplatzer Vascular Plug II and N-Butyl-2-Cyanoacrylate: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyun Kyung; Kwak, Hyo Sung; Han, Young Min [Dept. of Radiology, Chonbuk National University School of Medicine and Hospital, Chonju (Korea, Republic of); Kim, Young Kon [Dept. of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2011-04-15

    Treatment for an enterovaginal fistula should consider the location of an intestinal fistula. Most rectovaginal fistulas develop in the lower third of the vagina and can be treated surgically. Jejunovaginal fistulas can spontaneously close during conservative management. We report the first use of the Amplatzer vascular plug II (AVP II; AGA Medical Corp, Golden Valley, MN, USA) and the use of an N-butyl-2-cyanoacrylate (NBCA; Histoacryl, Braun, Melsungen, Germany)- iodized oil (Lipiodol Ultra-Fluid, Guerbet, Aulnay-sous-Bois, France) mixture for treatment of a patient with a jejunovaginal fistula which failed to close after conservative management. The patient did not have any vaginal discharge one day later after deployment of the AVP II.

  5. Percutaneous Treatment of a Jejunovaginal Fistula Using a Combination of the Amplatzer Vascular Plug II and N-Butyl-2-Cyanoacrylate: A Case Report

    International Nuclear Information System (INIS)

    Treatment for an enterovaginal fistula should consider the location of an intestinal fistula. Most rectovaginal fistulas develop in the lower third of the vagina and can be treated surgically. Jejunovaginal fistulas can spontaneously close during conservative management. We report the first use of the Amplatzer vascular plug II (AVP II; AGA Medical Corp, Golden Valley, MN, USA) and the use of an N-butyl-2-cyanoacrylate (NBCA; Histoacryl, Braun, Melsungen, Germany)- iodized oil (Lipiodol Ultra-Fluid, Guerbet, Aulnay-sous-Bois, France) mixture for treatment of a patient with a jejunovaginal fistula which failed to close after conservative management. The patient did not have any vaginal discharge one day later after deployment of the AVP II.

  6. Embolization of high-flow AVM nidus with n-butyl-2-cyanoacrylate derivative through a recanalized type 1 AmplatzerR vascular plug remaining from a previous proximal embolization: a case report

    International Nuclear Information System (INIS)

    Full text: Introduction: Arteriovenous malformation (AVM)s are well-known indications of liquid agent use to embolise the nidus, since proximal feeder embolization usually results in recurrence. Objectives and tasks: In this article, we aim to present that in a case with a previous recanalized proximal AmplatzerR vascular plug (AVP) embolization of a high flow pelvic AVM, to embolise the nidus readily with n butyl- 2-cyanoacrylate (n-BCA) derivative via recanalized AVP located in the proximal feeder is feasible. Material and methods:41-year-old male who had undergone several proximal embolization sessions by using AVP and coils due to high-flow pelvic AVM referred to our unit for a new embolization session because of recurrence established in the CT angiography examination. Results: In digital substraction angiography examination, a high flow AVM recanalization mostly fed by the anterior branches of right internal iliac artery was seen in the region of previous proximal embolization with AVP. A cobra catheter was navigated immediately proximal to the recanalized AVP and successful nidal embolization was achieved easily by using 15% n-BCA derivative diluted with iodized oil (lipiodol) via recanalized AVP. Conclusion: This case demonstrates the permeability of AVP's to liquid embolic agents, once they recanalize. In those cases, 15% n-BCA derivative diluted with iodized oil easily penetrates the recanalized AVP and enables distal nidal embolization

  7. Use of the Amplatzer Type 2 Plug for Flow Redirection in Failing Autogenous Hemodialysis Fistulae

    Energy Technology Data Exchange (ETDEWEB)

    Bozkurt, Alper, E-mail: bozkurtalper@yahoo.com; Kırbaş, İsmail, E-mail: drismailk@yahoo.com [Turgut Ozal University Hospital, Radiology Department (Turkey); Kasapoglu, Benan, E-mail: benankasapoglu@hotmail.com [Turgut Ozal University Hospital, Internal Medicine Department (Turkey); Teber, Mehmet Akif, E-mail: drteberma@hotmail.com [Ataturk Education and Training Hospital, Radiology Department (Turkey)

    2015-08-15

    PurposeTo present our experience with redirecting the outflow of mature arteriovenous fistulae (AVFs) in patients with cannulation and/or suboptimal flow problems by percutaneous intervention using the Amplatzer Vascular Plug II (AVP II).MethodsWe retrospectively reviewed patients who presented with difficulty in cannulation and/or suboptimal flow in the puncture zone of the AVF and who underwent intervention using the AVP II to redirect the outflow through a better cannulation zone from March 2009 to November 2012. The mean survival rate of all AVFs was estimated, and the effects of patient age, sex, and AVF age on the AVF survival time were determined.ResultsIn total, 31 patients (17 male and 14 female) with a mean age of 57.8 years (range, 20–79 years) were included. In 2 patients, the AVF failed within the first 15 days because of rapid thrombosis. In 9 patients, the new AVF route was working effectively until unsalvageable thrombosis developed. One of the 31 patients died 9 months before the last radiologic evaluation. The new AVF route was still being used for dialysis in the remaining 19 patients. The mean AVF survival rate was 1,061.4 ± 139.4 days (range, 788–1,334 days). Patient age, sex, and AVF age did not affect the survival time.ConclusionWe suggest that the AVP II is useful for redirecting the outflow of AVFs with cannulation problems and suboptimal flow. Patency of existing AVFs may be extended, thereby extending surgery-free or catheter intervention-free survival period.

  8. Use of the Amplatzer Type 2 Plug for Flow Redirection in Failing Autogenous Hemodialysis Fistulae

    International Nuclear Information System (INIS)

    PurposeTo present our experience with redirecting the outflow of mature arteriovenous fistulae (AVFs) in patients with cannulation and/or suboptimal flow problems by percutaneous intervention using the Amplatzer Vascular Plug II (AVP II).MethodsWe retrospectively reviewed patients who presented with difficulty in cannulation and/or suboptimal flow in the puncture zone of the AVF and who underwent intervention using the AVP II to redirect the outflow through a better cannulation zone from March 2009 to November 2012. The mean survival rate of all AVFs was estimated, and the effects of patient age, sex, and AVF age on the AVF survival time were determined.ResultsIn total, 31 patients (17 male and 14 female) with a mean age of 57.8 years (range, 20–79 years) were included. In 2 patients, the AVF failed within the first 15 days because of rapid thrombosis. In 9 patients, the new AVF route was working effectively until unsalvageable thrombosis developed. One of the 31 patients died 9 months before the last radiologic evaluation. The new AVF route was still being used for dialysis in the remaining 19 patients. The mean AVF survival rate was 1,061.4 ± 139.4 days (range, 788–1,334 days). Patient age, sex, and AVF age did not affect the survival time.ConclusionWe suggest that the AVP II is useful for redirecting the outflow of AVFs with cannulation problems and suboptimal flow. Patency of existing AVFs may be extended, thereby extending surgery-free or catheter intervention-free survival period

  9. Occlusion of pulmonary arteriovenous malformations by use of vascular plug

    DEFF Research Database (Denmark)

    Andersen, P E; Kjeldsen, A D

    2007-01-01

    Pulmonary arteriovenous malformations are commonly treated by embolization with coils or balloons to prevent cerebral complications and to raise the oxygenation of the blood. The Amplatzer vascular plug is a new occlusive device made of a self-expanding cylindrical nitinol mesh. It is fast and safe...... to position, and can be repositioned before final delivery. It is especially suited for embolization of large high-flow vessels as in pulmonary arteriovenous malformations with big feeding arteries. Two cases of successful use of the new device for treatment of large pulmonary arteriovenous...

  10. RE: Endovascular Treatment of Congenital Intrahepatic Portosystemic Shunts with Amplatzer Plugs

    International Nuclear Information System (INIS)

    In our paper entitled 'Endovascular treatment of congenital portal vein fistulas with the Amplatzer occlusion device' published in the Journal of Vascular and Interventional Radiology in 2004, we already reported the use of the AVP in the treatment of an intrahepatic portosystemic venous shunt. This situation does not undervalue the quality of the reported case, but for didactic purposes, we believe it is important to state that the work of Dr. Lee confirms, as was previously reported, that these devices are useful and safe for these rare situations.

  11. RE: Endovascular Treatment of Congenital Intrahepatic Portosystemic Shunts with Amplatzer Plugs

    Energy Technology Data Exchange (ETDEWEB)

    Sierre, Sergio; Alonso, Jose; Lipsich, Jose [Hospital Nacional de Pediatria ' JP Garrahan' , Combate de los Pozos, Buenos (Argentina)

    2012-01-15

    In our paper entitled 'Endovascular treatment of congenital portal vein fistulas with the Amplatzer occlusion device' published in the Journal of Vascular and Interventional Radiology in 2004, we already reported the use of the AVP in the treatment of an intrahepatic portosystemic venous shunt. This situation does not undervalue the quality of the reported case, but for didactic purposes, we believe it is important to state that the work of Dr. Lee confirms, as was previously reported, that these devices are useful and safe for these rare situations.

  12. Endovascular treatment of intralobar pulmonary sequestration with vascular plug: A case report

    International Nuclear Information System (INIS)

    Intralobar pulmonary sequestration is a rare entity, which requires surgical resection as the treatment of choice. Recently, endovascular treatment for occlusion of the feeding artery has been frequently used with the increased availability regarding a variety of embolic materials, such as gelatin sponge particles, polyvinyl alcohol particles, and coils. Authors described the successful treatment of intralobar pulmonary sequestration with a Type II Amplatzer Vascular Plug and antibiotic soaked gelatin sponge particles for complete occlusion of the feeding artery regarding intralolar pulmonary sequestration. Neither recanalization of the feeding artery for the sequestered lung nor other complications occurred during a 1 year follow up

  13. Oclusão do apêndice atrial esquerdo com o Amplatzer Cardiac Plug em pacientes com fibrilação atrial Left atrial appendage closure with the Amplatzer Cardiac Plug in patients with atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Ênio Eduardo Guérios

    2012-06-01

    Full Text Available FUNDAMENTO: A oclusão percutânea do apêndice atrial esquerdo (OAAE surgiu como alternativa à anticoagulação oral (AO para prevenção do acidente vascular cerebral (AVC em pacientes com fibrilação atrial não-valvular (FANV. OBJETIVO: Relatar os resultados imediatos e o seguimento clínico de pacientes submetidos a OAAE com o Amplatzer Cardiac Plug (ACP em um único centro de referência. MÉTODOS: Oitenta e seis pacientes consecutivos com FANV, contra-indicação à AO e escore CHADS2= 2,6±1,2 foram submetidos a OAAE com implante de ACP. Realizou-se seguimento clínico e ecocardiográfico no mínimo 4 meses após o implante. RESULTADOS: Todos os implantes foram guiados apenas por angiografia. O sucesso do procedimento foi de 99% (1 insucesso por tamponamento cardíaco e consequente suspensão da OAAE. Houve 4 complicações maiores (o tamponamento já referido, 2 AVCs transitórios e uma embolização com retirada percutânea da prótese e duas menores (um derrame pericárdico sem tamponamento e uma pequena comunicação interatrial evidenciada no seguimento. Houve 1 óbito hospitalar após 6 dias, não relacionado à intervenção. Todos os outros pacientes receberam alta sem AO. Após seguimento de 25,9 pacientes-ano (69 pacientes não houve AVCs nem embolizações tardias de próteses. O AAE estava completamente ocluído em 97% dos casos. Seis pacientes apresentaram evidência de trombo sobre a prótese, que desapareceram após reinstituição de AO por 3 meses. CONCLUSÃO: OAAE se associa a um alto índice de sucesso, um índice aceitável de complicações e resultados promissores a médio prazo, podendo ser considerada uma alternativa válida à OA na prevenção do AVC em pacientes com FANV.BACKGROUND: Percutaneous left atrial appendage closure (LAAC has emerged as an alternative to oral anticoagulation (OA for prevention of thromboembolic stroke in patients with non-valvular atrial fibrillation (NVAF. OBJECTIVE: To describe the

  14. Closing the gap between coil and balloon in the neurointerventional armamentarium? Initial clinical experience with a nitinol vascular occlusion plug

    Energy Technology Data Exchange (ETDEWEB)

    Gralla, Jan; Schroth, Gerhard; El-Koussy, Marwan; Brekenfeld, Caspar [University of Bern, Department of Diagnostic and Interventional Neuroradiology, Inselspital, Bern (Switzerland); Kickuth, Ralph [Interventional and Pediatric Radiology, Department of Diagnostic, Bern (Switzerland); Do, Dai-Do [University of Bern, Department of Angiology, Inselspital, Bern (Switzerland)

    2008-08-15

    The use of vascular plug devices for the occlusion of high-flow lesions is a relatively new and successful procedure in peripheral and cardiopulmonary interventions. We report on the use and efficiency of the Amplatzer vascular plug in a small clinical series and discuss its potential for occlusion of large vessels and high-flow lesions in neurointerventions. Between 2005 and 2007 four patients (mean age 38.5 years, range 16-62 years) were treated with the device, in three patients to achieve parent artery occlusion of the internal carotid artery, in one patient to occlude a high-flow arteriovenous fistula of the neck. The application, time to occlusion, and angiographic and clinical results and the follow-up were evaluated. Navigation, positioning and detachment of the device were satisfactory in all cases. No flow-related migration of the plug was seen. The cessation of flow was delayed by a mean of 10.5 min after deployment of the first device. In the procedures involving vessel sacrifice, two devices had to be deployed to achieve total occlusion. No patient experienced new neurological deficits; the 3-month follow-up revealed stable results. The Amplatzer vascular plug can be adapted for the treatment of high-flow lesions and parent artery occlusions in the head and neck. In this small series the use of the devices was uncomplicated and safe. The rigid and large delivery device and the delayed cessation of flow currently limit the device's use in neurointerventions. (orig.)

  15. Oclusão do apêndice atrial esquerdo com o Amplatzer Cardiac Plug em pacientes com fibrilação atrial

    Directory of Open Access Journals (Sweden)

    Ênio Eduardo Guérios

    2012-06-01

    Full Text Available FUNDAMENTO: A oclusão percutânea do apêndice atrial esquerdo (OAAE surgiu como alternativa à anticoagulação oral (AO para prevenção do acidente vascular cerebral (AVC em pacientes com fibrilação atrial não-valvular (FANV. OBJETIVO: Relatar os resultados imediatos e o seguimento clínico de pacientes submetidos a OAAE com o Amplatzer Cardiac Plug (ACP em um único centro de referência. MÉTODOS: Oitenta e seis pacientes consecutivos com FANV, contra-indicação à AO e escore CHADS2= 2,6±1,2 foram submetidos a OAAE com implante de ACP. Realizou-se seguimento clínico e ecocardiográfico no mínimo 4 meses após o implante. RESULTADOS: Todos os implantes foram guiados apenas por angiografia. O sucesso do procedimento foi de 99% (1 insucesso por tamponamento cardíaco e consequente suspensão da OAAE. Houve 4 complicações maiores (o tamponamento já referido, 2 AVCs transitórios e uma embolização com retirada percutânea da prótese e duas menores (um derrame pericárdico sem tamponamento e uma pequena comunicação interatrial evidenciada no seguimento. Houve 1 óbito hospitalar após 6 dias, não relacionado à intervenção. Todos os outros pacientes receberam alta sem AO. Após seguimento de 25,9 pacientes-ano (69 pacientes não houve AVCs nem embolizações tardias de próteses. O AAE estava completamente ocluído em 97% dos casos. Seis pacientes apresentaram evidência de trombo sobre a prótese, que desapareceram após reinstituição de AO por 3 meses. CONCLUSÃO: OAAE se associa a um alto índice de sucesso, um índice aceitável de complicações e resultados promissores a médio prazo, podendo ser considerada uma alternativa válida à OA na prevenção do AVC em pacientes com FANV.

  16. Oclusão percutânea do apêndice atrial esquerdo com o Amplatzer Cardiac PlugTM na fibrilação atrial

    Directory of Open Access Journals (Sweden)

    Márcio José Montenegro

    2012-02-01

    Full Text Available Fundamento: A fibrilação atrial está associada a acidentes vasculares embólicos que frequentemente resultam em morte ou invalidez. Eficaz na redução desses eventos, a anticoagulação possui várias limitações e vem sendo amplamente subutilizada. Mais de 90% dos trombos identificados nos portadores de fibrilação atrial sem doença valvar se originam no apêndice atrial esquerdo, cuja oclusão é investigada como uma alternativa à anticoagulação. Objetivo: Determinar a viabilidade da oclusão percutânea do apêndice atrial esquerdo em pacientes com alto risco de eventos embólicos e limitações ao uso de anticoagulação. Métodos: Relatamos a experiência inicial com o Amplatzer Cardiac PlugTM (St. Jude Medical Inc., Saint Paul, Estados Unidos em pacientes com fibrilação atrial não valvar. Foram selecionados pacientes com alto risco de tromboembolia, sangramentos maiores e contraindicações ao uso ou grande labilidade na resposta ao anticoagulante. Os procedimentos foram realizados por via percutânea, sob anestesia geral e com ecocardiografia transesofágica. O desfecho primário foi a presença de complicações periprocedimento e o seguimento programado incluiu reavaliação clínica e ecocardiográfica em 30 dias e por contato telefônico após nove meses. Resultados: Nos cinco pacientes selecionados se conseguiu a oclusão do apêndice atrial esquerdo sem complicações periprocedimento. Não houve eventos clínicos no seguimento. Conclusão: Ensaios clínicos controlados são necessários antes que o fechamento percutâneo do apêndice atrial esquerdo constitua uma alternativa à anticoagulação na fibrilação atrial não associada a doença valvar. Mas o dispositivo se mostrou promissor em pacientes com alto risco de embolia e restrições ao uso de anticoagulantes.

  17. Oclusão percutânea do apêndice atrial esquerdo com o Amplatzer Cardiac PlugTM na fibrilação atrial Percutaneous occlusion of left atrial appendage with the Amplatzer Cardiac PlugTM in atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Márcio José Montenegro

    2012-02-01

    Full Text Available Fundamento: A fibrilação atrial está associada a acidentes vasculares embólicos que frequentemente resultam em morte ou invalidez. Eficaz na redução desses eventos, a anticoagulação possui várias limitações e vem sendo amplamente subutilizada. Mais de 90% dos trombos identificados nos portadores de fibrilação atrial sem doença valvar se originam no apêndice atrial esquerdo, cuja oclusão é investigada como uma alternativa à anticoagulação. Objetivo: Determinar a viabilidade da oclusão percutânea do apêndice atrial esquerdo em pacientes com alto risco de eventos embólicos e limitações ao uso de anticoagulação. Métodos: Relatamos a experiência inicial com o Amplatzer Cardiac PlugTM (St. Jude Medical Inc., Saint Paul, Estados Unidos em pacientes com fibrilação atrial não valvar. Foram selecionados pacientes com alto risco de tromboembolia, sangramentos maiores e contraindicações ao uso ou grande labilidade na resposta ao anticoagulante. Os procedimentos foram realizados por via percutânea, sob anestesia geral e com ecocardiografia transesofágica. O desfecho primário foi a presença de complicações periprocedimento e o seguimento programado incluiu reavaliação clínica e ecocardiográfica em 30 dias e por contato telefônico após nove meses. Resultados: Nos cinco pacientes selecionados se conseguiu a oclusão do apêndice atrial esquerdo sem complicações periprocedimento. Não houve eventos clínicos no seguimento. Conclusão: Ensaios clínicos controlados são necessários antes que o fechamento percutâneo do apêndice atrial esquerdo constitua uma alternativa à anticoagulação na fibrilação atrial não associada a doença valvar. Mas o dispositivo se mostrou promissor em pacientes com alto risco de embolia e restrições ao uso de anticoagulantes.Background: Atrial fibrillation is associated with embolic strokes that often result in death or disability. Effective in reducing these events

  18. Endovascular Broad-Neck Aneurysm Creation in a Porcine Model Using a Vascular Plug

    International Nuclear Information System (INIS)

    Ruptured cerebral arterial aneurysms require prompt treatment by either surgical clipping or endovascular coiling. Training for these sophisticated endovascular procedures is essential and ideally performed in animals before their use in humans. Simulators and established animal models have shown drawbacks with respect to degree of reality, size of the animal model and aneurysm, or time and effort needed for aneurysm creation. We therefore aimed to establish a realistic and readily available aneurysm model. Five anticoagulated domestic pigs underwent endovascular intervention through right femoral access. A total of 12 broad-neck aneurysms were created in the carotid, subclavian, and renal arteries using the Amplatzer vascular plug. With dedicated vessel selection, cubic, tubular, and side-branch aneurysms could be created. Three of the 12 implanted occluders, two of them implanted over a side branch of the main vessel, did not induce complete vessel occlusion. However, all aneurysms remained free of intraluminal thrombus formation and were available for embolization training during a surveillance period of 6 h. Two aneurysms underwent successful exemplary treatment: one was stent-assisted, and one was performed with conventional endovascular coil embolization. The new porcine aneurysm model proved to be a straightforward approach that offers a wide range of training and scientific applications that might help further improve endovascular coil embolization therapy in patients with cerebral aneurysms.

  19. Endovascular Broad-Neck Aneurysm Creation in a Porcine Model Using a Vascular Plug

    Energy Technology Data Exchange (ETDEWEB)

    Muehlenbruch, Georg, E-mail: gmuehlenbruch@ukaachen.de; Nikoubashman, Omid; Steffen, Bjoern; Dadak, Mete [RWTH Aachen University, Department of Diagnostic and Interventional Neuroradiology, University Hospital (Germany); Palmowski, Moritz [RWTH Aachen University, Department of Nuclear Medicine, University Hospital (Germany); Wiesmann, Martin [RWTH Aachen University, Department of Diagnostic and Interventional Neuroradiology, University Hospital (Germany)

    2013-02-15

    Ruptured cerebral arterial aneurysms require prompt treatment by either surgical clipping or endovascular coiling. Training for these sophisticated endovascular procedures is essential and ideally performed in animals before their use in humans. Simulators and established animal models have shown drawbacks with respect to degree of reality, size of the animal model and aneurysm, or time and effort needed for aneurysm creation. We therefore aimed to establish a realistic and readily available aneurysm model. Five anticoagulated domestic pigs underwent endovascular intervention through right femoral access. A total of 12 broad-neck aneurysms were created in the carotid, subclavian, and renal arteries using the Amplatzer vascular plug. With dedicated vessel selection, cubic, tubular, and side-branch aneurysms could be created. Three of the 12 implanted occluders, two of them implanted over a side branch of the main vessel, did not induce complete vessel occlusion. However, all aneurysms remained free of intraluminal thrombus formation and were available for embolization training during a surveillance period of 6 h. Two aneurysms underwent successful exemplary treatment: one was stent-assisted, and one was performed with conventional endovascular coil embolization. The new porcine aneurysm model proved to be a straightforward approach that offers a wide range of training and scientific applications that might help further improve endovascular coil embolization therapy in patients with cerebral aneurysms.

  20. Application of Amplatzer vascular occluder in hepatic artery closure as a method of treatment of high-flow arterioportal fistula before liver transplantation

    International Nuclear Information System (INIS)

    Arterioportal fistula (APF) is an abnormal, direct connection between hepatic artery or its branch and the portal vein. Fistula can be acquired or, rarely, congenital. One of the acquired causes of fistula is a liver biopsy. Patients with liver cirrhosis are particularly vulnerable to its development due to the large number of performed biopsies. APF increases mortality and morbidity of liver transplantation procedure and may be a contraindication to it. The authors present a patient with liver cirrhosis, in whom percutaneous APF closure facilitated liver transplantation. We describe a case of a 50-year-old patient with liver cirrhosis and APF, probably formed as a result of liver biopsy. Due to the presence of a high-flow fistula, which elevated portal hypertension, patient did not qualify for the liver transplantation. Patient was transferred to the interventional radiology department, where the fistula’s vascular supply was endovascularly closed using the Amplatzer occluder. This subsequently enabled the execution of transplantation. Percutaneous closure of APF should be considered a relatively simple and fast-acting tool to facilitate or even enable liver transplant surgery. Currently, there are more and more products available such as e.g. Amplatzer occluder to simplify the procedure and shorten the duration of exposure to ionizing radiation

  1. Comparison of CT and MRI artefacts from coils and vascular plugs used for portal vein embolization

    International Nuclear Information System (INIS)

    Purpose: To retrospectively analyze the degree of artefacts in CT and MRI scans caused by coils and vascular plugs used for portal vein embolization (PVE). Materials and methods: All patients who underwent PVE between July 2011 and December 2012 and received either plug or coil embolization additional to particle embolization were retrospectively analyzed. Artefacts causes by embolization materials were measured in CT and MRI scans following PVE. Results: The sum of the artefact diameters caused from coils was significantly higher in CT (188.3 ± 26.1 mm) than in MRI T1 (50.5 ± 6.5 mm) or T2 imaging (39.5 ± 9.7 mm) (P < 0.05). In MRI, the diameter in T1 and T2 sequences did not differ significantly (P = 0.977). The sum of the artefact diameters from vascular plugs in MRI T1 sequences (62.5 ± 8.7 mm) was significantly higher than in CT (46.6 ± 4.8 mm; P < 0.05) and MRI T2 sequences (52.8 ± 3.8 mm; P < 0.05). Conclusion: PVE with particles and vascular plug causes significantly fewer artefacts than PVE with particles and coils on CT scans following embolization, which can be important in the event of vascular complications or in follow-up scans, should the patient become unresectable

  2. Bioabsorbable radiopaque water-responsive shape memory embolization plug for temporary vascular occlusion.

    Science.gov (United States)

    Wong, Yee Shan; Salvekar, Abhijit Vijay; Zhuang, Kun Da; Liu, Hui; Birch, William R; Tay, Kiang Hiong; Huang, Wei Min; Venkatraman, Subbu S

    2016-09-01

    We describe the preparation, characterization and evaluation of a biodegradable radiopaque water-triggered shape memory embolization plug for temporary vascular occlusion. The shape memory occluding device consists of a composite of a radio-opaque filler and a poly (dl-lactide-co-glycolide) (PLGA) blend, which was coated with a crosslinked poly (ethylene glycol) diacrylate (PEGDA) hydrogel. The mechanical properties, the degradation timeframe, the effect of programming conditions on the shape memory behaviour and the extent of radio-opacity for imaging were evaluated. Based on the tests, the mechanism responsible for the water-induced shape memory effect in such an embolization plug was elucidated. Suitable materials were optimized to fabricate an embolic plug prototype and its in vitro performance was evaluated as an occlusion rate (using a custom-built set up) and its biocompatibility. Finally, a feasibility study was conducted in vivo in a rabbit model to investigate the ease of device deployment, device migration and extent of vessel occlusion. The in vivo results demonstrated that the prototypes were visible under fluoroscopy and complete vascular occlusion occurred within 2 min of deployment of the prototypes in vivo. In conclusion, the developed embolization plug enables controlled and temporary vascular embolization, and is ready for safety studies. PMID:27322962

  3. Vascular plug-assisted retrograde transvenous obliteration of portosystemic shunts for refractory hepatic encephalopathy: a case report.

    Science.gov (United States)

    Park, Jonathan K; Cho, Sung-Ki; Kee, Stephen; Lee, Edward W

    2014-01-01

    While balloon-assisted retrograde transvenous obliteration (BRTO) has been used for two decades in Asia for the management of gastric variceal bleeding, it is still an emerging therapy elsewhere. Given the shunt closure brought about by the procedure, BRTO has also been used for the management of portosystemic encephalopathy with promising results. Modified versions of BRTO have been developed, including plug-assisted retrograde transvenous obliteration (PARTO), where a vascular plug is deployed within a portosystemic shunt. To our knowledge, we present the first North American case of PARTO in the setting of a large splenorenal shunt for the management of portosystemic encephalopathy. PMID:24744943

  4. Congenital Intrahepatic Portosystemic Venous Shunt and Liver Mass in a Child Patient: Successful Endovascular Treatment with an Amplatzer Vascular Plug (AVP)

    OpenAIRE

    Lee, Sae Ah; Lee, Young Seok; Lee, Kun Song; Jeon, Gyeong Sik

    2010-01-01

    A congenital intrahepatic portosystemic shunt is a rare anomaly; but, the number of diagnosed cases has increased with advanced imaging tools. Symptomatic portosystemic shunts, especially those that include hyperammonemia, should be treated; and various endovascular treatment methods other than surgery have been reported. Hepatic masses with either an intra- or extrahepatic shunt also have been reported, and the mass is another reason for treatment. Authors report a case of a congenital intra...

  5. Aortic iatrogenic perforation during transseptal puncture and successful occlusion with Amplatzer ductal occluder in a case of mitral paravalvular leak closure.

    Science.gov (United States)

    Mijangos-Vázquez, Roberto; García-Montes, José Antonio; Zabal-Cerdeira, Carlos

    2016-08-01

    Complications of transseptal puncture are significant and potentially life threatening. Aortic perforation is one of these complications and it needs to be repaired immediately. We report the case of a 48-year-old female with a history of rheumatic mitral valve disease. She underwent three previous mitral valve replacements. Her last echocardiogram reported an anterolateral leak in the mitral prosthesis. Catheterization was performed. During the procedure, when attempting to perform transseptal puncture, catheterization was complicated by a forcefully puncture of the aortic root by the Brockenbrough needle followed by an immediately advancement of an 8-Fr Mullins sheath. We decided to leave the 8-Fr sheath in the aortic root recognizing the danger of removing the sheath and finally we advanced a 6/4 mm Amplatzer ductal occluder (ADO I) through the Mullins sheath and under fluoroscopy and TEE guidance we achieved a successful deployment of the device and closure of the perforation. Subsequently, the paravalvular leak was closed with an Amplatzer Vascular Plug (AVP III 10/5 mm). There are only three cases of a similar technique for the same injury in which the authors describe successful closing of aortic perforation with percutaneous closure devices. Our case is the first described during a mitral paravalvular leak closure. It is also the first to describe a different technique of leaving the Mullins sheath in the aortic root and advancing the Amplatzer device through it to achieve successful closure of the aortic perforation. We preferred the percutaneous closure over open-heart repair. © 2015 Wiley Periodicals, Inc. PMID:26489701

  6. Plugging indicator

    International Nuclear Information System (INIS)

    It is often difficult to measure a plugging temperature when the impurity concentration in liquid sodium is low. Then, the plugging temperature is considered to be inferior to 1100C. Sometimes, a more precise indication is required. We propose a use for the plugging indicator which satisfies this type of requirement. A partial plugging of the indicator orifice is produced and increases at a constant temperature. A mathematical model describes this growth: it is based mainly on the kinetics of Na2O and NaH crystal growth and links the plugging time to oxygen or hydrogen concentrations. (orig.)

  7. Clinical experience with the percutaneously inserted Amplatz vena caval filter

    International Nuclear Information System (INIS)

    The Amplatz filter is a 14-F vena caval filter designed for percutaneous insertion and retrieval. Thirty filters were inserted. The indications for placement were anticoagulant failure (four cases) and contraindication to anticoagulation (26 cases). Radiologic, pathologic, or clinical follow-up (average, 10 months) was available in 27 patients. Results include one case of recurrent pulmonary embolism (4%), nine cases of caval thrombosis (33%), and two cases of deep venous thrombosis in the insertion leg (7%). Filter migration did not occur in any case. The Amplatz filter is easily inserted and well tolerated by the patient. Although effective in preventing recurrent pulmonary embolism, it has a relatively high incidence of caval thrombosis

  8. Plugging solution

    Energy Technology Data Exchange (ETDEWEB)

    Vagner, G.R.; Garaev, A.S.; Guzenko, L.P.; Khaber, N.V.; Kruglitskii, N.N.; Kurochkin, B.M.; Shumilov, V.A.

    1981-03-23

    Proposed is a plugging solution which contains cement, hydrophilic biosilica, polymer, and water, and which is distinguished by the fact that in order to increase the strength properties of the stone with simultaneous increase in its resistance to the effect of corrosive bed water under conditions of normal temperatures, as hydrophilic biosilica the solution contains carboxy aerosil or aminoethoxy aerosil, and as a polymer, carboxylate divinyl styrene latex and it also contains sodium with the following ingredient ratio, wt %: 63.47-66.08% cement, 0.66-1.28% carboxylate divinyl styrene latex, 1.26-1.32% sodium chloride, 0.22-0.36% carboxy aerosil or aminoethoxy aerosil, and the rest water. The plugging solution is distinguished by the fact that carboxy aerosil or aminoethoxy aerosil have a specific surface of 50-300 m/g.

  9. Plug Power

    International Nuclear Information System (INIS)

    This presentation described Plug Power's GenDrive hydrogen fuel cell unit that supplies the power needs for folk lift trucks used in high-throughput distribution and high-volume manufacturing operations. The system offers an alternative to lead acid batteries, providing maximum performance at all times during use. The system is particularly useful in the material handling industry, where the revenue generated is based on operator uptime and lift truck productivity. The use of the system allows customers to reduce operational costs and expand valuable floor space by eliminating batteries and associated recharging infrastructure. Fuel cell units also reduce the wear on truck motors. Truck operators can easily and safely refuel at hydrogen fueling stations in 1-5 minutes. GenDrive works with all major OEM lift trucks, making the transition seamless. Commercial customers are investing in this solution to improve their current operations. In 2008, Plug Power sold to Wal-Mart, Bridgestone Firestone and Nestle. Most notably, Central Grocers purchased 220 fuel cell units for a new greenfield distribution center. Plug Power currently has more than 380 systems in operation

  10. Plug Power

    Energy Technology Data Exchange (ETDEWEB)

    Marsh, A. [Plug Power Inc., New York, NY (United States)

    2009-07-01

    This presentation described Plug Power's GenDrive hydrogen fuel cell unit that supplies the power needs for folk lift trucks used in high-throughput distribution and high-volume manufacturing operations. The system offers an alternative to lead acid batteries, providing maximum performance at all times during use. The system is particularly useful in the material handling industry, where the revenue generated is based on operator uptime and lift truck productivity. The use of the system allows customers to reduce operational costs and expand valuable floor space by eliminating batteries and associated recharging infrastructure. Fuel cell units also reduce the wear on truck motors. Truck operators can easily and safely refuel at hydrogen fueling stations in 1-5 minutes. GenDrive works with all major OEM lift trucks, making the transition seamless. Commercial customers are investing in this solution to improve their current operations. In 2008, Plug Power sold to Wal-Mart, Bridgestone Firestone and Nestle. Most notably, Central Grocers purchased 220 fuel cell units for a new greenfield distribution center. Plug Power currently has more than 380 systems in operation.

  11. Plugging solution

    Energy Technology Data Exchange (ETDEWEB)

    Sharipov, A.U.; Polyakov, V.N.; Yangirova, I.Z.

    1982-06-10

    Proposed is a plugging solution containing cement, modified methyl cellulose, and water. In order to decrease the viscosity in time with the preservation of filtration and strength properties of the solution and stone, it also contains wastes of the production of 4,4-dimethyl dioxane-1,3 with following ratio of components, mass%: 66.0-67.0% cement; 0.07-0.15 modified methyl cellulose, 0.13-0.33% wastes from the production of 4,4-dimethyl dioxane-1,3, and the rest water.

  12. Plugging material

    Energy Technology Data Exchange (ETDEWEB)

    Kuznetsov, Yu.S.; Kravtsov, V.M.; Mavlyutov, M.R.; Spivak, A.I.; Trutnev, G.A.

    1982-01-01

    Plugging material is proposed which includes Portland cement and quartz sand. In order to improve the strength of the stone and sedimentation stability of the cement mud and to guarantee expansion during hardening of the stone in the interval 20-180/sup 0/C, it also contains solid residue of wastes from soda production thermally treated at temperature 850-900/sup 0/C with the following ratio of components (% by mass): Portland cement 60-80, quartz sand 15-20; solid residue of soda production 5-20.

  13. Plugging composition

    Energy Technology Data Exchange (ETDEWEB)

    Akhrimenko, V.Ye.; Antonov, V.A.; Bulatov, A.I.; Gagay, G.I.; Levshin, V.A.; Minakova, V.I.

    1982-01-01

    A plugging composite is proposed for preparing muds containing binding agent with polymer of styrene type. It is distinguished by the fact that in order to improve the quality of the mud by improving its heat resistance, the polymer of styrene type used is a copolymer of styrene and divinylbenzene-resin KU-2 with the following ratio of ingredients, % by mass: binding agent 50-90; styrene and divinylbenzene-resin KU-2 copolymer 10-50. The composite is also distinguished by the fact that it contains as the binding agent Portland cement or Portland cement with granulated slag.

  14. Assessment of the geometric profile of the Amplatzer and Cardioseal septal occluders by three dimensional echocardiography

    OpenAIRE

    Acar, P; Saliba, Z; Bonhoeffer, P; Sidi, D; Kachaner, J

    2001-01-01

    OBJECTIVE—To apply three dimensional echocardiography to describe the geometric profile of the Amplatzer and Cardioseal occluders after deployment for closure of atrial septal defect.
METHODS—20 patients (mean (SD) age, 14 (5) years) were enrolled for transcatheter closure of a secundum atrial septal defect with the Amplatzer occluder (10) or with the Cardioseal occluder (10). The two populations were matched for the stretched diameter of the defect (mean 18 (6) mm). The profile of the two oc...

  15. Percutaneous ventricular septal defect closure with Amplatzer devices resulting in severe tricuspid regurgitation.

    Science.gov (United States)

    Matyal, Robina; Wang, Angela; Mahmood, Feroze

    2013-11-15

    While percutaneous intervention is an alternative for patients who are not surgical candidates, the rate of morbidity and mortality is comparable to open repair. Appending the reported complications associated with percutaneous intervention (device mal-positioning, dislodgement, and entrapment in the sub-valvular apparatus), we report mechanical damage to the tricuspid valve (TV). Percutaneous closure with an Amplatzer septal occluder device was attempted on three patients who developed a ventricular septal defects (VSD) after myocardial infarction. In all three cases, damage to the tricuspid leaflet was noted post-procedure. The accompanying severe tricuspid regurgitation led to right ventricular failure, even in the patients where the VSD was considered successfully occluded. Despite successful deployment of the Amplatzer device, complications with catheter manipulation may still arise. Damage to the TV can occur during percutaneous VSD closure with Amplatzer device. Periprocedure TEE monitoring can detect damage to the tricuspid leaflets. PMID:23553968

  16. Completely endoscopic removal of a dislocated Amplatzer atrial septal defect closure device.

    Science.gov (United States)

    Bonatti, Johannes; Bonaros, Nikolaos; Müller, Silvana; Bartel, Thomas

    2008-02-01

    Surgical treatment of residual shunts after transcatheter occlusion of atrial septal defect or patent foramen ovale is reported in approximately one to two percent of these percutaneous interventions. Minimally invasive surgery on the atrial septum is getting more and more common but little data is available on Amplatzer device explantation through limited access. No completely endoscopic device removal has been described previously. We report a case of a 57-year-old woman in whom an Amplatzer device was removed in a robotic totally endoscopic fashion through ports only using the daVinci telemanipulation system. PMID:17951273

  17. Rotating arc spark plug

    Science.gov (United States)

    Whealton, John H.; Tsai, Chin-Chi

    2003-05-27

    A spark plug device includes a structure for modification of an arc, the modification including arc rotation. The spark plug can be used in a combustion engine to reduce emissions and/or improve fuel economy. A method for operating a spark plug and a combustion engine having the spark plug device includes the step of modifying an arc, the modifying including rotating the arc.

  18. Reactor vessel sealing plug

    International Nuclear Information System (INIS)

    This invention relates to an apparatus and method for sealing the cold leg nozzles of a nuclear reactor pressure vessel from a remote location during maintenance and inspection of associated steam generators and pumps while the pressure vessel and refueling canal are filled with water. The apparatus includes a sealing plug for mechanically sealing the cold leg nozzle from the inside of a reactor pressure vessel. The sealing plugs include a primary and a secondary O-ring. An installation tool is suspended within the reactor vessel and carries the sealing plug. The tool telescopes to insert the sealing plug within the cold leg nozzle, and to subsequently remove the plug. Hydraulic means are used to activate the sealing plug, and support means serve to suspend the installation tool within the reactor vessel during installation and removal of the sealing plug

  19. Treatment of patent ductus arteriosus by the use of an Amplatz canine ductal occluder device.

    Science.gov (United States)

    White, Pam

    2009-04-01

    A 7-month-old female, spayed border collie was referred to the Ontario Veterinary College due to a continuous murmur noted by the referring veterinarian prior to ovariohysterectomy. Auscultation confirmed a grade VI/VI continuous murmur. An echocardiogram confirmed patent ductus arteriosus (PDA). An Amplatz canine ductal occluder device was successfully placed for occlusion of blood flow though the ductus. PMID:19436449

  20. The clinical application of Amplatzer duct occluder Ⅱ in treating perimembranous ventricular septal defects

    International Nuclear Information System (INIS)

    Objective: To discuss the feasibility of using Amplatzer duct occluder Ⅱ to treat perimembranous ventricular septal defects. Methods: Transcatheter closure by using Amplatzer duct occluder Ⅱ was carried out in two female infants with small perimembranous ventricular septal defect. One female infant was 3 years old. The echocardiogram showed that the diameter of VSD was 5.5 mm in left ventricle side and 2.3 mm in right ventricle side. The distance of the upper border of VSD to aortic valve was 4 mm. The other female infant was 2 years and 10 months old, the diameter of VSD was 7.8 mm in left ventricle side and 2.0 mm in right ventricle side. The distance between the upper border of VSD to aortic valve was 5.8 mm. Results: For one infant the 4 by 4 mm Amplatzer duct occluder Ⅱ and 5 F TorqVue low profile delivery catheter was employed, while for the other infant 3 by 4 mm Amplatzer duct occluder Ⅱ and 4 F delivery catheter was used. In accordance with the standard procedure the arteriovenous pathway was set up first, than the left shed and right shed were released in turn. After the operation, echocardiogram showed that there was no residual shunt and aortic regurgitation in occluded site, but mild atrioventricular regurgitation was seen in one infant. The electrocardiogram performed two days after procedure was normal. Conclusion: Transcatheter closure by using Amplatzer duct occluder Ⅱ is very effective for the treatment of small perimembranous ventricular septal defects in infants. This technique has some advantages such as the use of small delivery catheter, minimally-invasive to the vessels, etc. In a short-term after the operation no complications such as residual shunt, valve regurgitation, arrhythmia, etc. occur. (authors)

  1. The Twin Amplatz Sheath Method: A Modified Technique of Percutaneous Cystolithotripsy for Large Bladder Stones in Female Patients

    Science.gov (United States)

    Kumar, Amit; Dalela, Deepansh; Dalela, Divakar; Goel, Apul; Paul, Sagorika; Sankhwar, Satya N.

    2013-01-01

    To minimize the operative time and to avoid open cystolithotomy in women with large bladder stone (>5 cm), we present here a modification of percutaneous cystolithotomy, a well-described standard procedure for urinary bladder stones. With this technique, suprapubic percutaneous access was achieved under cystoscopic guidance. The suprapubic tract was dilated and an Amplatz sheath of 30 Fr was placed. Simultaneously, the urethra was sequentially dilated with fascial dilators and a 28 Fr Amplatz sheath was guided into the bladder and the foot end of the table lowered to 20° to facilitate high-speed outflow of irrigant and stone particles. A 26.5 Fr nephroscope was passed through the suprapubic Amplatz sheath and the stone was fragmented by intracorporeal pneumatic device keeping the stone close to the proximal end of the urethral Amplatz. These maneuvers help in washing out stone fragments periurethrally and keeping the endoscopic vision clear while breaking the stone. PMID:24741433

  2. Simultaneous stent implantation for coarctation of the aorta and closure of patent ductus arteriosus using the Amplatzer duct occluder.

    Science.gov (United States)

    Hakim, F; Hawelleh, A A; Goussous, Y; Hijazi, Z M

    1999-05-01

    We report on a 13-year-old girl with coarctation of the aorta and patent ductus arteriosus who underwent successful simultaneous stent implantation for the coarctation and catheter closure of the ductus using an Amplatzer duct occluder. PMID:10385155

  3. Plug Load Data

    Data.gov (United States)

    National Aeronautics and Space Administration — We provide MATLAB binary files (.mat) and comma separated values files of data collected from a pilot study of a plug load management system that allows for the...

  4. Live/Real Time Three-Dimensional Trans Esophageal Echocardiographic Findings in Amplatzer ASD Closure Devices in Adults

    Directory of Open Access Journals (Sweden)

    Fatemeh Nabavizadeh

    2012-09-01

    Full Text Available Six female patients aged from 19 to 73 years, with ostium secundum atrial septal defect underwent closure procedure with Amplatzer septal occluder device. Three-dimensional Echocardiography (3D-TEE was done during the procedure or one day after the procedure. 3D-TEE provides incremental value over Two- dimensional trans-esophageal echocardiography in measuring Amplatzer septal occluder disc sizes and correlates well with manufacture device size. 3D-TEE will surely prove to increase the technical efficiency and it will become an important tool for the interventionists for periprocedural evaluation of device closures.

  5. Fuel rod plugs

    International Nuclear Information System (INIS)

    Purpose: To prevent the formation of voids to the inside of welded portion in fuel rod plugs. Constitution: A fuel rod is tightly sealed by welding end plugs at both ends of a fuel can charged with nuclear fuel material. For the welding of the end plug, laser welding has now been employed with the reason of increasing the welding efficiency and reducing the welding heat distortion. However, if the end plug is laser-welded to the end of the fuel can in the conventional form, there is a problem that voids are liable to be formed near the deepest penetration in the welding portion. That is, gases evolved near the deepest penetration remains in a key-hole like welded metal portion to result in voids there. Accordingly, grooves capable of passing the laser beam key hole therethrough are disposed along the circumferential direction of the pipe at the end plug welded portion in the fuel can. In this way, since gases generating near the deepest penetration are discharged into the grooves, the key hole-like welded metal is completely filled and voids are not formed. (Kamimura, M.)

  6. Clearance of a Mucus Plug

    Science.gov (United States)

    Bian, Shiyao; Zheng, Ying; Grotberg, James B.

    2008-11-01

    Mucus plugging may occur in pulmonary airways in asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. How to clear the mucus plug is essential and of fundamental importance. Mucus is known to have a yield stress and a mucus plug behaves like a solid plug when the applied stresses are below its yield stress τy. When the local stresses reaches τy, the plug starts to move and can be cleared out of the lung. It is then of great importance to examine how the mucus plug deforms and what is the minimum pressure required to initiate its movement. The present study used the finite element method (FEM) to study the stress distribution and deformation of a solid mucus plug under different pressure loads using ANSYS software. The maximum shear stress is found to occur near the rear transition region of the plug, which can lead to local yielding and flow. The critical pressure increases linearly with the plug length and asymptotes when the plug length is larger than the half channel width. Experimentally a mucus simulant is used to study the process of plug deformation and critical pressure difference required for the plug to propagate. Consistently, the fracture is observed to start at the rear transition region where the plug core connects the films. However, the critical pressure is observed to be dependent on not only the plug length but also the interfacial shape.

  7. A plugging solution

    Energy Technology Data Exchange (ETDEWEB)

    Bulatov, A.I.; Arakelyan, A.A.; Gen' , O.U.; Krutikova, N.I.; Lezhenin, V.V.; Repyakhova, T.M.; Rudomino, M.V.; Ryabova, L.I.

    1983-01-01

    The purpose of this invention is to increase the setting time of a binder at temperatures between 200 and 300 degrees centigrade, to reduce the water loss of the solution and to improve the strength of the plugging rock. This is achieved by an arrangement whereby the plugging solution consisting of a binder, water and an organic element setting retarder contains mononuclear complexones of nitryltrimethylphosphonic acid for use as the setting retarder, with the following component ratios (percentage by weight): binder 70.71 to 72.80; organic component setting retarder .0072 to 1; water the remaining.

  8. Plugging device for nuclear pipes

    International Nuclear Information System (INIS)

    The plugging device assembled near an access opening is used for plugging the primary pipes. This plugging device comprises a rim flexible joint put in mechanical pressure by the displacement of mechanical pieces. This joint has a central compartment pressurizable. This joint is fixed by a stirrup-piece and a shaft in support on the tube plate

  9. Amplatzer occlusion of paravalvular leak of mitral mechanical prosthesis following a reoperation for thrombosed mitral mechanical prosthesis

    OpenAIRE

    Nikolic, Aleksandar; Schranz, Ditmaer; HRISTOV, Nikola; Mitrev, Zan

    2008-01-01

    We describe a case of a 46-year-old woman with dehiscence and paravalvular leak of a second-time replaced mitral mechanical prosthesis, successfully treated with Amplatzer occlusion of the paravalvular leak, thus avoiding a second reoperation and improving the patient’s symptoms.

  10. Transcatheter closure of secundum atrial septal defect using an Amplatzer septal occluder

    Institute of Scientific and Technical Information of China (English)

    孔祥清; 曹克将; 杨荣; 许迪; 盛燕辉; 黄峻; 马文珠

    2002-01-01

    Objective To evaluate the safety and efficacy of the Amplatzer septal occluder for transcatheter closure in patients with secundum atrial septal defect (ASD Ⅱ). Methods Patients with clinically confirmed ASD Ⅱ were recommended for transcatheter closure of ASD Ⅱ. Results 30 ASD Ⅱ patients (20 females) underwent transcatheter closure at a median age of 18.4 years (5-55 years). Both the stretched diameters of ASDs and the sizes of the devices were from 18 to 34?mm (25±7?mm). The successful placement rate was 100%. The rest shunt documented by color Doppler, was immediately after implantation in 40% of patients, in 9.9% after 24 hours, and in 3.3% trace at 3 months. No serious complications were observed. There was improvement in symptoms and in cardiac size. Septal motion abnormalities normalized in all patients after 3 months follow-up. Conclusion The Amplatzer septal occluder is a safe and effective device for transcatheter closure of ASD Ⅱ. Long-term follow-up is still required before widespread clinical use can be recommended.

  11. Providing free autopoweroff plugs

    DEFF Research Database (Denmark)

    Jensen, Carsten Lynge; Hansen, Lars Gårn; Fjordbak, Troels;

    2012-01-01

    Experimental evidence of the effect of providing households with cheap energy saving technology is sparse. We present results from a field experiment in which autopoweroff plugs were provided free of charge to randomly selected households. We use propensity score matching to find treatment effects...... on metered electricity consumption for different types of households. We find effects for single men and couples without children, while we find no effect for single women and households with children. We suggest that this could be because of differences in saving potential (e.g. some households do...

  12. Vascular Cures

    Science.gov (United States)

    ... our CEO Board of Directors Scientific Advisory Board History of Vascular Cures Impact Contact Us Vascular Disease What is Vascular Disease? Education and Awareness Vascular Diseases Abdominal Aortic Aneurysm Aortic ...

  13. Hemostatic completion of percutaneous nephrolithotomy using electrocauterization and a clear amplatz renal sheath

    Directory of Open Access Journals (Sweden)

    Ho Song Yu

    2016-02-01

    Full Text Available ABSTRACT Background and Purpose A tubeless PCNL can reduce postoperative pain, the need for analgesics, hospital stay, and postoperative urinary leakage. However, perioperative or delayed bleeding remains the primary postoperative concern. We demonstrate a simple and cost-effective method to develop a clear nephrostomy tract after completion of a tubeless PCNL. Materials and Methods Four consecutive patients with renal calculi >3cm underwent a tubeless PCNL. We used a 24 Fr nephroscope and a 24 Fr transurethral resectoscope. Intraoperative urologist-directed percutaneous renal access was performed under fluoroscopy. After calculi removal, active bleeders were identified via a clear Amplatz renal sheath. The sheath provided excellent visualization of the nephrostomy tract for the detection of bleeders and surrounding structures. Bleeders were electrocauterized using a roller barrel electrode. During extraction of the renal sheath, the surgeon can confirm hemostasis in the tract and apply intermittent suction. Results Bleeding primarily originated from the torn calyeceal mucosa and the parenchyma. Tract electrocauterization was successful. All patients had mild hematuria, which resolved within two days. The average hemoglobin decrease was 1.65g/dL (0.8-2.1 and no patients required a transfusion. No perioperative complications occurred. On postoperative day 2, the patients could ambulate without a Foley catheter. During three months of follow-up, delayed bleeding or percutaneous urine leakage did not occur. Conclusions Electrocauterization with a roller barrel electrode and a clear Amplatz renal sheath is an effective method to obtain hemostasis after completion of a PCNL. Our technique is cost-effective and readily adapted without the need for additional instruments.

  14. Polysaccharides and bacterial plugging

    Energy Technology Data Exchange (ETDEWEB)

    Fogler, H.S.

    1991-11-01

    Before any successful application of Microbial Enhanced Oil Recovery process can be realized, an understanding of the cells' transport and retentive mechanisms in porous media is needed. Cell transport differs from particle transport in their ability to produce polysaccharides, which are used by cells to adhere to surfaces. Cell injection experiments have been conducted using Leuconostoc cells to illustrate the importance of cellular polysaccharide production as a transport mechanism that hinders cell movement and plugs porous media. Kinetic studies of the Leuconostoc cells, carried out to further understand the plugging rates of porous media, have shown that the cells' growth rates are approximately equal when provided with monosaccharide (glucose and fructose) or sucrose. The only difference in cell metabolism is the production of dextran when sucrose is supplied as a carbon source. Experimentally it has also been shown that the cells' growth rate is weakly dependent upon the sucrose concentration in the media, and strongly dependent upon the concentration of yeast extract. The synthesis of cellular dextran has been found to lag behind cell generation, thus indicating that the cells need to reach maturity before they are capable of expressing the detransucrase enzyme and synthesizing insoluble dextran. Dextran yields were found to be dependent upon the sucrose concentration in the media. 10 refs., 9 figs., 9 tabs.

  15. Rotating plug bearing and seal

    Science.gov (United States)

    Wade, Elman E.

    1977-01-01

    A bearing and seal structure for nuclear reactors utilizing rotating plugs above the nuclear reactor vessel. The structure permits lubrication of bearings and seals of the rotating plugs without risk of the lubricant draining into the reactor vessel below. The structure permits lubrication by utilizing a rotating outer race bearing.

  16. Mechanics Model of Plug Welding

    Science.gov (United States)

    Zuo, Q. K.; Nunes, A. C., Jr.

    2015-01-01

    An analytical model has been developed for the mechanics of friction plug welding. The model accounts for coupling of plastic deformation (material flow) and thermal response (plastic heating). The model predictions of the torque, energy, and pull force on the plug were compared to the data of a recent experiment, and the agreements between predictions and data are encouraging.

  17. Rotating plug bearing and seal

    International Nuclear Information System (INIS)

    Disclosed is a bearing and seal structure for nuclear reactors utilizing rotating plugs above the nuclear reactor vessel. The structure permits lubrication of bearings and seals of the rotating plugs without risk of the lubricant draining into the reactor vessel below. The structure permits lubrication by utilizing a rotating outer race bearing. 19 claims, 3 figures

  18. The exploration of the closure of patent ductus arteriosus with Amplatzer occluder through single venous approach under ultrasound monitoring

    International Nuclear Information System (INIS)

    Objective: To explore the feasibility and effectiveness of transcatheter closure of patent ductus arteriosus (PDA) with Amplatzer occluder by using single venous approach method under ultrasound monitoring. Methods: During the period from May 2003 to April 2010, transcatheter closure of PDA were performed in 123 cases. Of the 123 patients, the procedure was accomplished by using arteriovenous dual approach method in 46 and by using single venous approach method in 77. All the procedures were monitored by ultrasound. The shape, size of PDA and immediate therapeutic results were checked with angiography in arteriovenous dual approach method or with ultrasonography in single venous approach method. The size of Amplatzer occluder was individually selected according to the smallest diameter of PDA. Echocardiography was performed at 3 days, one, 6 and 12 months after the procedure to evaluate the results. Results: Successful device placement with the initially selected occluder was obtained in 118 cases. In 4 cases the procedure was eventually completed after a bigger occluder was employed to replace the initial one, while in one case a smaller occluder had to use to replace the first one. The technical success rate was 100%. Conclusion: The transcatheter closure of PDA with Amplatzer occluder under ultrasound monitoring by single venous approach method is clinically effective and feasible. Being technically simple and time-saving, this single venous approach method is of great value in clinical practice. (authors)

  19. Transcatheter Closure of a Chronic Iatrogenic Arteriovenous Fistula Between the Carotid Artery and the Brachiocephalic Vein with an Amplatzer Duct Occluder in Combination with a Carotid Stent

    International Nuclear Information System (INIS)

    We report an original method of transcatheter closure of an arteriovenous fistula using the combination of an Amplatzer PDA occluder and a carotid stent. The fistula was between the left carotid artery and the brachiocephalic vein. The patient had significant left-to-right shunt and was highly symptomatic. Due to the large orifice and pseudoaneurysmatic enlargement of the fistula, we had to use a large Amplatzer PDA occluder and the protruding part of the PDA device disk had to be covered with a carotid stent. The fistula was completely closed. The patient stopped having symptoms and, 2 years after the procedure, the effect persists.

  20. Home-made fenestrated amplatzer occluder for atrial septal defect and pulmonary arterial hypertension

    Institute of Scientific and Technical Information of China (English)

    Fabio Dell'Avvocata; Gianluca Rigatelli; Paolo Cardaioli; Massimo Giordan

    2011-01-01

    We report the management of a patient with secundum atrial septal defect (ASD)and severe pulmonary hypertension.A 65-year-old male with recently diagnosed atrial serital defect was referred to our centre for decompensated right heart failure with rest and exercise induced dispnea and severe pulmonary hypertension.Right heart catheterization confirmed a mean pulmonary pressure of about 55 mmHg and a Qp/Qs of 2.7.An occlusion test with a compliant large balloon demonstrated partial fall of pulmonary arterial pressure.The implantation of a home-made fenestrated Amplatzer ASD Occluder (ASO) was planned in order to decrease lefttoright shunt and promote further decrease of pulmonary arterial pressure in the long-term.Thus,by means of mechanical intracardiac echocardiography study with a 9F 9 MHz Ultralce catheter(Boston Scientific Corp.),we selected a 34 mm ASO for implantation.Four millimeter fenestration was made inflating a 4 ntm non-compliant coronary balloon throughout the waist of the ASO,which was successfully implanted under intracardiac echocardiography.After six months,a decrease of pulmonary arterial pressure to 24 mmHg and full compensated right heart failure was observed on transthoracic echocardiography and clinical examination.This case suggests that transcatheter closure with home-made fenestrated ASD in elderly patients with severe pulmonary hypertension is feasible.

  1. Tratamiento endovascular de una fuga paraprotésica mitral con dispositivo Amplatzer®

    Directory of Open Access Journals (Sweden)

    Alberto Sciegata

    2012-10-01

    Full Text Available El leak o fuga paraprotésica mitral se presenta entre el 5 y el 17% de los pacientes tratados con cirugía de reemplazo valvular. En general, los defectos son únicos, la mayoría se encuentran localizados en la región postero-medial del anillo valvular y solo la tercera parte produce reflujo de grado grave. El cierre percutáneo por vía endovascular es una alternativa terapéutica válida en pacientes con elevado riesgo para re-operación. La estrategia de abordaje depende de la localización, tamaño, morfología y relaciones adyacentes del o los defectos. El procedimiento debe ser realizado por profesionales con experiencia en el tratamiento de cardiopatías estructurales y en el manejo de estos dispositivos de cierre, y se considera imprescindible la utilización de un ecocardiograma transesofágico tridimensional. Se presenta el caso de un paciente con una fuga paraprotésica valvular mitral que fue cerrada con un dispositivo Amplatzer ® introducido en forma percutánea desde la vena femoral.

  2. Endocarditis and Incomplete Endothelialization 12 Years after Amplatzer Septal Occluder Deployment.

    Science.gov (United States)

    Nguyen, Allan K; Palafox, Brian A; Starr, Joanne P; Gates, Richard N; Berdjis, Farbouch

    2016-06-01

    A 4-year-old boy had a 15-mm atrial septal defect repaired percutaneously with use of an Amplatzer Septal Occluder. At age 16 years, he presented with a week's history of fever, chills, dyspnea, fatigue, and malaise. Cultures grew methicillin-sensitive Staphylococcus aureus. A transesophageal echocardiogram showed a 1.25 × 1.5-cm pedunculated mass on the left aspect of the atrial septum just superior to the mitral valve, and a smaller vegetation on the right inferior medial aspect of the septum. At surgery, visual examination of both sides of the septum revealed granulation tissue, the pedunculated mass, the small vegetation, and exposed metal wires that suggested incomplete endothelialization of the occluder. We removed the occluder and patched the septal defect. The patient returned to full activity after 4 months and was asymptomatic 3 years postoperatively. Our report reinforces the need for further investigation into prosthetic device endothelialization, endocarditis prophylaxis, and recommended levels of physical activity in patients whose devices might be incompletely endothelialized. In addition to reporting our patient's case, we review the medical literature on this topic. PMID:27303238

  3. Ventricular Septal Perforation after Biventricular Takotsubo Cardiomyopathy Successfully Repaired with an Amplatzer Device: First Report in the Literature

    Science.gov (United States)

    Rodríguez, Alfredo E.; Fernandez-Pereira, Carlos; Mieres, Juan; Ascarrunz, Diego; Gabe, Eduardo; Rodríguez-Granillo, Alfredo Matías; Frattini, Romina; Stuzbach, Pablo

    2016-01-01

    A 79-year-old female was admitted with sudden onset dyspnea, mild oppressive chest pain, and severe anxiety disorder. Patient had history of hypertension, dyslipidemia, smoking, and chronic obstructive pulmonary disease. On admission blood pressure was 160/90 and heart rate was 130 bpm. Transthoracic echocardiography (TE) and contrast tomography showed a thin septum with an abnormal left and right ventricular contraction with an “apical ballooning” pattern and mild increase of cardiac enzymes. At the 4th day of admission, the patient presented symptoms and signs of congestive heart failure and developed cardiogenic shock. EKG showed an inversion of T waves in all precordial leads. In a new TE, a ventricular septal perforation (VSP) in the apical portion of the septum was seen. Coronary angiogram showed angiographically “normal” coronary arteries. With a diagnosis of VSP in takotsubo cardiomyopathy, a percutaneous procedure to repair the VSP was performed 11 days after admission. The VSP was closed with an Amplatzer device. TE performed 24 hours after showed significant improvement of ventricular function and good apposition of the Amplatzer device. Three days later she was discharged from the hospital. To our knowledge, this is the first reported case of a VSP in a TCM repaired percutaneously with an occluder device.

  4. Interventional Closure of Patent Foramen Ovale (PFO with Amplatzer PFO Occluder in Patients with Paradoxical Cerebral Embolism

    Directory of Open Access Journals (Sweden)

    Ali Mohammad Haji Zeinali

    2006-08-01

    Full Text Available Background: Percutaneous transcatheter closure has been proposed as an alternative to surgical closure or long-term anticoagulation in patients with presumed paradoxical embolism and patent foramen ovale (PFO. Methods: There were two symptomatic patients (29 and 47 years old who underwent percutaneous transcatheter closure of PFO after at least two events of cerebral ischemia; one embolic event had occurred under anti-platelet therapy. For both patients, Amplatzer PFO occluder measuring 25 mm in diameter were used. In both cases, complete occlusion by color Doppler and transesophageal contrast echocardiography investigation was achieved after the procedure and lasted at least up to 3 months after implantation as determined by our follow up. Mean fluoroscopy time was 16.7 minutes. Results: Percutaneous transcatheter closure was technically successful in both patients (100%. No residual shunt was seen at the end of the procedure or in follow-ups. In-hospital follow-up was uneventful. At a mean follow-up of 3 months, no recurrent embolic neurological events were observed. Conclusion: Transcatheter closure of PFO with Amplatzer PFO occluder devices is a safe and effective therapy for patients with previous paradoxical embolism PFO. Percutaneous closure is associated with a high success rate, low incidence of hospital complications, and freedom of cerebral ischemic events.

  5. Usefulness of Transesophageal Echocardiography for Transcatheter Closure of Ostium Secundum Atrial Septum Defect with the Amplatzer Septal Occluder

    Directory of Open Access Journals (Sweden)

    Chun-Yu Chen

    2005-12-01

    Full Text Available Background: Transcatheter closure of ostium secundum atrial septum defect (ASDIIusing the new self-centering occluder, Amplatzer Septal Occluder (ASO,has been well developed in recent years. We describe the importance and roleof transesophageal echocardiography (TEE in the selection and closure ofsuch defects.Methods: Thirty patients referred for transcatheter closure of ASDII by ASO wereenrolled in this study. During catheterization, two-dimensional TEE was performedon all patients during and after transcatheter closure. ASD size andmorphology were assessed by TEE before catheterization. The ASDstretched diameter was also measured by TEE and fluoroscopy.Results: With the aid of TEE, transcatheter closure of an ASD was successfully, safelyand effectively performed on 29 patients. The mean ASD diameter determinedby TEE was 17.4 4.8 mm. The mean stretched diameters measuredby TEE and fluoroscopy were 18.7 5.6 mm and 17.9 5.5 mm, respectively.The mean device diameter was 19 5.6 mm. Immediate completeclosure was documented by color Doppler TEE in 29 patients. Complicationswere encountered in one patient, with the device becoming dislodged into themain pulmonary artery. The device was retrieved by surgery and the defectwas repaired in the operating room.Conclusions: Transcatheter closure of ASDs using an Amplatzer device is feasible, safeand effective. Two-dimensional TEE can provide useful information before,during and after transcatheter closure of ASDs.

  6. SNS Inner Plug Shipping Cask Analysis

    International Nuclear Information System (INIS)

    Calculations were performed to evaluate the dose rates outside the shipping cask containing the Spallation Neutron Source (SNS) inner plug assembly. The analysis consisted of simulating the proton beam interaction with the SNS target, activation calculations with the determined neutron flux levels and assumed SNS operation schedule, and calculation of the decay gamma-rays propagation through the inner plug and shipping cask. Several materials were considered for the inner plug. The results provide guidance for the finalization of the plug design

  7. The NAHIF* Plug-in-Magnet

    CERN Multimedia

    CERN Audiovisual Unit

    1981-01-01

    * North Area High Intensity Facility of the CERN SPS. The beamlines with target stations and the plug-in magnets - The plug-in magnet to be removed for repair - The lifting bar and tool for the vacuum connector - The control stand - Controls for vacuum connector tool - The plug-in vacuum connector - Liftingbar with the automatic pins for magnets - The gravitational automatic pin - The plug-in kit in action.

  8. SAMI Automated Plug Plate Configuration

    CERN Document Server

    Lorente, Nuria P F; Goodwin, Michael

    2012-01-01

    The Sydney-AAO Multi-object Integral field spectrograph (SAMI) is a prototype wide-field system at the Anglo-Australian Telescope (AAT) which uses a plug-plate to mount its 13 x 61-core imaging fibre bundles (hexabundles) in the optical path at the telescope's prime focus. In this paper we describe the process of determining the positions of the plug-plate holes, where plates contain three or more stacked observation configurations. The process, which up until now has involved several separate processes and has required significant manual configuration and checking, is now being automated to increase efficiency and reduce error. This is carried out by means of a thin Java controller layer which drives the configuration cycle. This layer controls the user interface and the C++ algorithm layer where the plate configuration and optimisation is carried out. Additionally, through the Aladin display package, it provides visualisation and facilitates user verification of the resulting plates.

  9. Seal device for shield plug

    International Nuclear Information System (INIS)

    Purpose: To surely seal cover gases at a position nearer to the reactor core of a shield plug in LMFBR type reactors. Constitution: A shield plug is formed with through holes for insertion of a stopper or a through-cylinder. A step is provided to the through hole at the interium of the thickness of the shield plug and a seal ring is disposed on the step. The seal ring is retained on the side of the stopper or the through-cylinder by means of a holding member. The seal ring is urged to the step of the stopper by the own weight of the stopper or the through-cylinder to thereby seal the cover gases. Since the seal ring is retained on the side of the stopper or the through-cylinder, the seal ring is pulled up together with the extraction of the stopper or the through-cylinder and can be maintained or repaired with ease. (Ikeda, J.)

  10. Halliburton Composite Bridge Plug Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Starbuck, J.M.; Luttrell, C.R.; Aramayo, G.

    2005-01-15

    The overall objectives of this CRADA were to assist Halliburton in analyzing a composite bridge plug and to determine why their original design was failing in the field. In Phase 1, finite element analyses were done on the original composite slip design and several alternative designs. The composite slip was the component in the bridge plug that was failing. The finite element code ABAQUS was used for these calculations and I-DEAS was used as the pre- and post-processor in the analyses. Several different designs and materials were analyzed and recommendations were made towards improving the design. In Phase 2, the objective was to develop finite element models that would accurately represent the deformations in the entire all-composite 4-1/2' diameter bridge plug assembly. The finite element code LS-DYNA was used and the results from this effort were intended to expand Halliburton's composite design and analysis capabilities with regard to developing future composite components for downhole tools. In addition to the finite element modeling, this effort involved the utilization of micromechanics to determine the necessary composite material properties that were needed as input for finite element codes.

  11. Unusual systemic venous Collateral channels to left atrium causing desaturation after Fontan operation closed percutaneously

    Directory of Open Access Journals (Sweden)

    Ashutosh Marwah

    2013-01-01

    Full Text Available We present an unusual cause of progressive cyanosis in a child appearing 2 years after successful Fontan surgery for tetralogy of Fallot with hypoplastic right ventricle. The cause of cyanosis was identified as one large venous channel draining into the left atrium. The channel was closed by Amplatzer vascular plug resulting in improvement of oxygen saturation.

  12. Plug Load Behavioral Change Demonstration Project

    Energy Technology Data Exchange (ETDEWEB)

    Metzger, I.; Kandt, A.; VanGeet, O.

    2011-08-01

    This report documents the methods and results of a plug load study of the Environmental Protection Agency's Region 8 Headquarters in Denver, Colorado, conducted by the National Renewable Energy Laboratory. The study quantified the effect of mechanical and behavioral change approaches on plug load energy reduction and identified effective ways to reduce plug load energy. Load reduction approaches included automated energy management systems and behavioral change strategies.

  13. Plug into 'the modernizing machine'!

    DEFF Research Database (Denmark)

    Krejsler, John B.

    2013-01-01

    . Individual bodies and minds simultaneously produce academic subjectivities by plugging into these transformative machinic forces and are produced as they are traversed by them. What is experienced as stressful closures vis-à-vis new opportunities depends to a great extent upon how these producing...... reforms before and after this law are productions of those struggles that change what it means to work as an academic subject at a university. This is staged through a host of new social technologies such as development contracts, appraisal interviews, individual performance reviews and so forth...

  14. Multimeediaetendus : Opera Gets Plugged / Eve Arpo

    Index Scriptorium Estoniae

    Arpo, Eve

    2008-01-01

    Eesti Muusika- ja Teatriakadeemia lühiooperite õhtul "Opera Gets Plugged" etendunud lavastustest - Monika Mattieseni "DMeeter" ja Age Hirve "Tuleloitsija": Mõlema lavastaja ja projektijuht Liis Kolle

  15. VESGEN Software for Mapping and Quantification of Vascular Regulators

    Science.gov (United States)

    Parsons-Wingerter, Patricia A.; Vickerman, Mary B.; Keith, Patricia A.

    2012-01-01

    VESsel GENeration (VESGEN) Analysis is an automated software that maps and quantifies effects of vascular regulators on vascular morphology by analyzing important vessel parameters. Quantification parameters include vessel diameter, length, branch points, density, and fractal dimension. For vascular trees, measurements are reported as dependent functions of vessel branching generation. VESGEN maps and quantifies vascular morphological events according to fractal-based vascular branching generation. It also relies on careful imaging of branching and networked vascular form. It was developed as a plug-in for ImageJ (National Institutes of Health, USA). VESGEN uses image-processing concepts of 8-neighbor pixel connectivity, skeleton, and distance map to analyze 2D, black-and-white (binary) images of vascular trees, networks, and tree-network composites. VESGEN maps typically 5 to 12 (or more) generations of vascular branching, starting from a single parent vessel. These generations are tracked and measured for critical vascular parameters that include vessel diameter, length, density and number, and tortuosity per branching generation. The effects of vascular therapeutics and regulators on vascular morphology and branching tested in human clinical or laboratory animal experimental studies are quantified by comparing vascular parameters with control groups. VESGEN provides a user interface to both guide and allow control over the users vascular analysis process. An option is provided to select a morphological tissue type of vascular trees, network or tree-network composites, which determines the general collections of algorithms, intermediate images, and output images and measurements that will be produced.

  16. Vascular MR

    International Nuclear Information System (INIS)

    This project investigates cardiac gated gradient echo pulses sequences for vascular MR imaging. These pulse sequences have been used to acquire and display MR projection angiograms. The authors have applied these methods in two distinct populations of patients for evaluation and comparison with standard angiography. Twenty patients with abdominal aortic aneurysms, and 35 patients with aortoiliac atherosclerotic disease or peripheral vascular disease were investigated using this method and the results are presented

  17. Vascular Dementia

    OpenAIRE

    Maria Alekseyevna Cherdak; O. V. Uspenskaya

    2015-01-01

    Vascular dementia is one of the most common causes of dementia after Alzheimer's disease, causing around 15% of cases. However, unlike Alzheimer's disease, there are no licensed treatments for vascular dementia. Progress in the specialty has been difficult because of uncertainties over disease classification and diagnostic criteria, controversy over the exact nature of the relation between cerebrovascular pathology and cognitive impairment, and the paucity of identifiable tractable treatment ...

  18. Experiência inicial no fechamento percutâneo da comunicação interatrial com a prótese de Amplatzer Initial experience in percutaneous occlusion of atrial septal defects with the Amplatzer device

    Directory of Open Access Journals (Sweden)

    Valmir F. Fontes

    1998-03-01

    Full Text Available OBJETIVO: Analisar a experiência inicial no fechamento percutâneo da comunicação interatrial ostium secundum (CIA OS com a prótese de Amplatzer. MÉTODOS: Sete pacientes foram submetidos ao procedimento através da via venosa anterógrada, orientados pela ecocardiografia transesofágica (ETE e sob anestesia geral. Uma criança era portadora de 2 CIA e de canal arterial (CA. As CIA medidas pelo ETE variaram de 8,7 a 20mm. Um ecocardiograma transtorácico foi realizado na manhã seguinte do procedimento. RESULTADOS: Oito próteses foram implantadas nos 7 pacientes com sucesso. Em um paciente, o CA foi ocluído na mesma sessão com mola de Gianturco, tendo surgido taquicardia supraventricular durante a oclusão de uma das CIA, controlada com adenosina. Todos receberam alta hospitalar na manhã seguinte, com oclusão total dos defeitos. CONCLUSÃO: O procedimento mostrou-se seguro, eficaz e versátil, podendo ser considerado como uma alternativa terapêutica inicial em pacientes selecionados com CIA OS.PURPOSE: To evaluate our initial experience with percutaneous closure of secundum type atrial septal defects (ASD with the Amplatzer septal occluder. METHODS: Seven patients underwent occlusion by anterograde approach, under general anesthesia and transesophageal echocardiography (TEE guidance. One child had 2 ASD and a patent ductus arteriosus (PDA. The ASD size ranged from 8,7 to 20mm as measured by TEE. A transthoracic echocardiogram was performed in the morning after the procedure. RESULTS: Eight devices were successfully implanted in 7 patients and the PDA was occluded with a Gianturco coil at the same session. In this patient, there was an episode of supraventricular tachycardia during the occlusion of one ASD which was reverted with adenosin. All patients were discharged the day after, with complete occlusion of all defects. CONCLUSION: The procedure is safe, effective and versatile. It can be applied as an initial alternative to the

  19. Multiservice utility plug for remote fuel reprocessing

    International Nuclear Information System (INIS)

    This paper presents the design of a multiservice utility plug and drive system to be used for reliably engaging and disengaging all utility connections automatically that serve large portable equipment modules. The modules are arranged into a fuel processing production line within the Fuels and Materials Examination Laboratory. The utility plugs allow the modules to be easily replaced, rearranged or removed for maintenance

  20. Mastering Eclipse plug-in development

    CERN Document Server

    Blewitt, Alex

    2014-01-01

    If you are a Java developer who is familiar with the Eclipse plug-in environment, this book covers the advanced concepts that you need to know to achieve true expertise. Prior experience in creating Eclipse plug-ins is assumed for this book.

  1. Plug-In Tutor Agents: Still Pluggin'

    Science.gov (United States)

    Ritter, Steven

    2016-01-01

    "An Architecture for Plug-in Tutor Agents" (Ritter and Koedinger 1996) proposed a software architecture designed around the idea that tutors could be built as plug-ins for existing software applications. Looking back on the paper now, we can see that certain assumptions about the future of software architecture did not come to be, making…

  2. Sealing end plug of nuclear fuel rod

    International Nuclear Information System (INIS)

    An upper end plug of a nuclear fuel rod comprises an end plug main body having a diameter substantially equal with an outer diameter of a cladding tube, and an open-top portion formed integrally with the end plug main body by way of a connection portion. The open top portion is a cylindrical member having the outer diameter substantially equal with the inner diameter of the cladding tube and having a tapered portion formed at the top end. The connection portion has a tapered surface having a diameter on the side of the open-top portion equal with the outer diameter of the open-top portion and having a diameter on the side of the end plug main body greater than the maximum inner diameter of the cladding tube. The upper end plug is inserted under pressure to the cladding tube and the joining portion between the cladding tube and the upper end plug is welded under pressure. The welded portion between the upper end plug and the cladding tube is uniformly welded circumferentially, so that neither molten metal is urged to the inner wall of the cladding tube, nor porosity is formed at the inside of the molten metal. In addition, sealing is ensured by the tapered surface disposed at the connection portion of the upper end plug, and causing no failure occurs in the wall thickness of the welded metal due to swelling. (I.N.)

  3. CIRSE Vascular Closure Device Registry

    International Nuclear Information System (INIS)

    Purpose: Vascular closure devices are routinely used after many vascular interventional radiology procedures. However, there have been no major multicenter studies to assess the safety and effectiveness of the routine use of closure devices in interventional radiology. Methods: The CIRSE registry of closure devices with an anchor and a plug started in January 2009 and ended in August 2009. A total of 1,107 patients were included in the registry. Results: Deployment success was 97.2%. Deployment failure specified to access type was 8.8% [95% confidence interval (95% CI) 5.0–14.5] for antegrade access and 1.8% (95% CI 1.1–2.9) for retrograde access (P = 0.001). There was no difference in deployment failure related to local PVD at the access site. Calcification was a reason for deployment failure in only 5.9 cm, and two vessel occlusions. Conclusion: The conclusion of this registry of closure devices with an anchor and a plug is that the use of this device in interventional radiology procedures is safe, with a low incidence of serious access site complications. There seems to be no difference in complications between antegrade and retrograde access and other parameters.

  4. Numerical Investigation of Separated Plug Nozzle Flow

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Modern analysis techniques that provide improved viability have enabled further investigation of plug nozzle rocket engines as advanced launch vehicle concepts. A plug nozzle for future single-stage-to-orbit vehicles in China has been designed, and the flow field in the plug nozzle has been studied numerically for different ambient pressures. Calculations were performed by solving the Navier-Stokes equations for an ideal gas. Turbulence is modelled using the k-ε turbulence model. The advantages of the plug nozzles are the external expansion, which automatically adapts to external pressure variations, and the short compact design for high expansion ratios. Expansion waves, compression shocks, and the separated base flow dominate the flow structures and affect the plug nozzle rocket engine performance.

  5. Hydrate plug decomposition: Measurements and modeling

    Energy Technology Data Exchange (ETDEWEB)

    Yousif, M.H.; Dunayevsky, V.A.

    1995-12-31

    Depressurization (venting) is almost the only option available to remove hydrate blockages from subsea natural gas or gas condensate pipelines. This process is normally applied with little or no accurate information about the plug location, size or composition. Hydrate decomposition by depressurization is a heat and mass transfer dependent process. Quantifying this dependency is necessary to perform an optimum plug removal scheme. In this paper, a moving boundary mathematical model is developed to predict the decomposition rate of a hydrate plug under various depressurization scenarios. The model was validated experimentally by measuring the rate of decomposition of hydrate plugs in a 2 inch internal diameter, 38.5 inch long pipe. The motion of the hydrate plug/gas interface is tracked by 16 pairs of infrared light transmitters and receivers diametrically positioned across the pipe.

  6. Manipulating liquid plugs in microchannel with controllable air vents

    OpenAIRE

    Liu, Hao-Bing; Ting, Eng Kiat; Gong, Hai-Qing

    2012-01-01

    An air venting element on microchannel, which can be controlled externally and automatically, was demonstrated for manipulating liquid plugs in microfluidic systems. The element’s open and closed statuses correspond to the positioning and movement of a liquid plug in the microchannel. Positioning of multiple liquid plugs at an air venting element enabled the merging and mixing of the plugs. Besides these basic functions, other modes of liquid plug manipulations including plug partitioning, mu...

  7. Plug-in Hybrid Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Goodman, Angie; Moore, Ray; Rowden, Tim

    2013-09-27

    Our main project objective was to implement Plug-in Electric Vehicles (PEV) and charging infrastructure into our electric distribution service territory and help reduce barriers in the process. Our research demonstrated the desire for some to be early adopters of electric vehicles and the effects lack of education plays on others. The response of early adopters was tremendous: with the initial launch of our program we had nearly 60 residential customers interested in taking part in our program. However, our program only allowed for 15 residential participants. Our program provided assistance towards purchasing a PEV and installation of Electric Vehicle Supply Equipment (EVSE). The residential participants have all come to love their PEVs and are more than enthusiastic about promoting the many benefits of driving electric.

  8. Separator plugs for liquid helium

    Science.gov (United States)

    Lee, J. M.; Yuan, S. W. K.; Hepler, W. A.; Frederking, T. H. K.

    1984-01-01

    Work performed during Summer 1984 (from June to Sept. 30) in the area of porous media for use in low temperature applications is discussed. Recent applications are in the area of vapor - liquid phase separation, pumping based on the fountain effect and related subsystems. Areas of potential applications of the latter are outlined in supplementary work. Experimental data have been developed. The linear equations of the two-fluid model are inspected critically in the light of forced convection evidence reported recently. It is emphasized that the Darcy permeability is a unique throughput quantity in the porous media application areas whose use will permit meaningful comparisons of data not only in one lab but also within a group of labs doing porous plug studies.

  9. Friction Pull Plug Welding in Aluminum Alloys

    Science.gov (United States)

    Brooke, Shane A.; Bradford, Vann

    2012-01-01

    NASA's Marshall Space Flight Center (MSFC) has recently invested much time and effort into the process development of Friction Pull Plug Welding (FPPW). FPPW, is a welding process similar to Friction Push Plug Welding in that, there is a small rotating part (plug) being spun and simultaneously pulled (forged) into a larger part. These two processes differ, in that push plug welding requires an internal reaction support, while pull plug welding reacts to the load externally. FPPW was originally conceived as a post proof repair technique for the Space Shuttle fs External Tank. FPPW was easily selected as the primary weld process used to close out the termination hole on the Constellation Program's ARES I Upper Stage circumferential Self-Reacting Friction Stir Welds (SR-FSW). The versatility of FPPW allows it to also be used as a repair technique for both SR-FSW and Conventional Friction Stir Welds. To date, all MSFC led development has been concentrated on aluminum alloys (2195, 2219, and 2014). Much work has been done to fully understand and characterize the process's limitations. A heavy emphasis has been spent on plug design, to match the various weldland thicknesses and alloy combinations. This presentation will summarize these development efforts including weld parameter development, process control, parameter sensitivity studies, plug repair techniques, material properties including tensile, fracture and failure analysis.

  10. End plug welding method for control rod

    International Nuclear Information System (INIS)

    A cladding tube of a control rod has a coating layer of plated hard chromium or the like on the outer surface of the tube main body. The outer edge of an end plug to be attached to the end portion of the cladding tube has a tapered face opposing to the end portion of the cladding tube. The end plug is inserted under pressure to the end portion of the cladding tube in a state where neutron absorbers are contained and a coil spring is inserted in the cladding tube. Electric current is applied between the tube main body and the end plug in this state. The tube main body and the end plug are heated by their intrinsic resistance and contact resistance up to a weldable temperature. The tube main body and the end plug are joined by an urging pressure applied between the tube main body and the end plug. Since the end plug is welded to the end portion of the cladding tube at the circumference thereof by resistance welding, there is no worry of intruding the coating material to the welding portion, thereby enabling to attain satisfactory welding. (I.N.)

  11. Patent ductus arteriosus equipment and technique. Amplatzer duct occluder: intermediate-term follow-up and technical considerations.

    Science.gov (United States)

    Thanopoulos, B D; Hakim, F A; Hiari, A; Tsaousis, G S; Paphitis, C; Hijazi, Z M

    2001-04-01

    Between May 1997 and June 2000, 69 patients, ages 0.1 to 34 years, underwent attempted anterograde transcatheter closure of a patent ductus arteriosus (PDA) using the Amplatzer Duct Occluder (ADO). The ADO is a cone-shaped, self-centering, and repositionable occluder made of nitinol wire mesh. A 5Fr to 7Fr sheath was used for the delivery of the device. The mean PDA diameter (at the pulmonary end) was 4.6 +/- 1.9 mm (range 1 mm-8.5 mm). Sixty-seven of the 69 patients had successful device placement. The mean ADO smallest diameter was 6.9 +/- 1.8 mm (range 4 mm-12 mm). Complete angiographic closure occurred in 62 (92.5%) of 67 patients (95% confidence interval, 88.22%-98.77%). In five patients, there was a trivial residual shunt immediately after the procedure. At 24 hours, color Doppler flow imaging revealed complete closure in all 67 (100%) patients. The unsuccessful attempts occurred in two patients with a small, 1-mm diameter native PDA and residual PDA after surgical occlusion. Fluoroscopy time was 7.6 +/- 1.8 minutes (4 min-18 min). No complications were observed. At a median follow-up of 1.5 years (range 0.25 to 3.2 years), all patients had complete closure without complications. We conclude that transcatheter closure using the ADO is a highly effective and safe treatment for most patients with PDA. PMID:12053313

  12. Upper end plug of fuel rod

    International Nuclear Information System (INIS)

    The present invention concerns a seal-welding of an upper end plug of a fuel rod for nuclear fuels conducted in a final stage of molding fabrication of the fuel rod in a pressurized helium gas. A welding protrusion is formed at the periphery of a vent hole on the upper surface of the upper end plug, and the welding protrusion is melted by irradiation of laser beams. The melted protrusion intrudes into the end portion of the bent hole by capillary to close the vent hole. The upper end plug can be closed by an extremely simple operation of irradiating the laser beams to the protrusion. Control for electrode gap on every fuel rods and exchange for the electrodes as in TIG welding can be saved, thereby enabling to speed up and simplify the sealing operation for the upper end plug. (N.H.)

  13. Instrumented model pile tests on sand plugs

    Energy Technology Data Exchange (ETDEWEB)

    Haaren, L.J.C. van; Verruijt, A. [Delft Univ. of Technology (Netherlands); Kolk, H.J. [Fugro Engineers B.V., Leidschendam (Netherlands)

    1995-12-31

    0pen ended piles develop internal frictional resistance between the internal soil plug end the pile wall during axial loading. Current pipe pile design practice assumes that the ultimate internal skin friction is of the same order of magnitude as the outer skin friction. This paper describes a series of laboratory pile load tests on instrumented model pipe piles, designed to investigate the development of plug stresses and skin friction along the plug length during pile loading. The piles contain sand columns of various relative densities and of different heights. The soil plugs are loaded to failure under fully drained conditions. The test data indicate that internal skin friction in sand can be substantially higher than assumed in conventional design practice. This finding could lead to significant economical savings on future pipe pile foundations in sand.

  14. Modular, Plug and Play, Distributed Avionics Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of this SBIR effort was to prove the viability of an Ethernet version of the MicroSat Systems, Inc. (MSI) modular, plug and play (PnP) spacecraft...

  15. Hybrid and Plug-in Electric Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-05-20

    Hybrid and plug-in electric vehicles use electricity either as their primary fuel or to improve the efficiency of conventional vehicle designs. This new generation of vehicles, often called electric drive vehicles, can be divided into three categories: hybrid electric vehicles (HEVs), plug-in hybrid electric vehicles(PHEVs), and all-electric vehicles (EVs). Together, they have great potential to reduce U.S. petroleum use.

  16. Elastocapillary powered manipulation of liquid plug in microchannels

    Science.gov (United States)

    George, D.; Anoop, R.; Sen, A. K.

    2015-12-01

    We report the manipulation of a liquid plug inside a rectangular microchannel, when one of the channel walls is a deformable membrane, which adjoins another parallel microchannel. Elastocapillary flow of a driving liquid (DL) through the adjoining microchannel, when approaches the plug, tries to pull the membrane near the plug, which is initially deflected into the plug, towards the DL. The plug is transported due to a differential pressure that develops across the plug owing to the increase in the radius of curvature of the trailing meniscus of the plug. A theoretical model is proposed to predict the plug velocity, which depends on a parameter J and plug length L ˜ . The predictions of the theoretical model show good agreement with experimental data. The dynamic behaviour of the plug and DL is presented and discussed.

  17. Development of explosive plugging for steam generator tubes

    International Nuclear Information System (INIS)

    This paper reports the development of explosive plugging techniques as a repair method for leaking steam generator tubes. The study has been in progress since 1977 and results confirm that the explosive plugging method is applicable to the steam generator. The following developmental tests were performed. 1. Preliminary test - Kind and amount of explosive, shape of plug, stand-off, initiation method, etc. 2. Evaluation test - Shearing test, measurement of bonded zone (U.T. and microscopic observation), He-leakage test, water pressure test, hardness of plug and tube after plugging, P.T. for plugged tube plate surface, etc. 3. Re-plugging after failed plugging 4. Demonstration plugging of a 50 MW steam generator 5. Thermal shock test 6. Sodium vapour atmosphere test The results of these tests indicate that the explosive plugging method is effective for the repair of leaking tubes in steam generators. (author)

  18. What Is Vascular Disease?

    Science.gov (United States)

    ... our CEO Board of Directors Scientific Advisory Board History of Vascular Cures Impact Contact Us Vascular Disease What is Vascular Disease? Education and Awareness Vascular Diseases Abdominal Aortic Aneurysm Aortic ...

  19. Diabetes and Vascular Disease

    Science.gov (United States)

    ... our CEO Board of Directors Scientific Advisory Board History of Vascular Cures Impact Contact Us Vascular Disease What is Vascular Disease? Education and Awareness Vascular Diseases Abdominal Aortic Aneurysm Aortic ...

  20. Test plan: Potash Core Test. WIPP experimental program borehole plugging

    International Nuclear Information System (INIS)

    The Potash Core Test will utilize a WIPP emplaced plug to obtain samples of an in-situ cured plug of known mix constituents for bench scale testing. An earlier effort involved recovery at the salt horizon of Plug 217, a 17 year old plug in a potash exploration hole for bond testing, but the lack of particulars in the emplacement precluded significant determination of plug performance

  1. Long-Term Follow-up of Patent Ductus Arteriosus Closure with the Amplatzer Duct Occluder in Children

    Directory of Open Access Journals (Sweden)

    Mostafa Behjati-Ardakani

    2015-10-01

    Full Text Available Background: Transcatheter closure of patent ductus arteriosus (PDA has become an alternative treatment to surgery. We evaluated the long-term results of the transcatheter closure of PDA with the Amplatzer Duct Occluder (ADO in children.Methods: Between May 2004 and October 2012, 138 children with PDA (43 males and 95 females underwent transcatheter PDA closure. Clinical, electrocardiographic, echocardiographic, and hemodynamic data were assessed pre and postprocedurally and at follow-up.Results: The mean age of the patients at procedure was 3.53 ± 2.43 years (range = 1.1 to 9.5 years, mean weight was11.9±4.6 kg (range = 6 to 29 kg, median pulmonary end diameter of the PDA was 5 mm (range = 4 to 15 mm, and median diameter of the ADO was 8 mm (range = 6 to 16 mm. The mean follow-up time was 43.4 ± 23.5 months (range = 13.5 to98 months.The devices were successfully deployed in 136 (98.5% patients. Device embolization occurred in 2 patients, immediately in one patient and during the first postprocedural night in the other patient. The first patient had percutaneous device retrieval, followed by implantation of a larger device. The second patient had surgical device removal and PDA ligation. Immediately after device implantation, trivial to mild residual shunts were detected in 112 (80% patients; all the shunts, however, disappeared 24 hours after the procedure. One patient had left pulmonary artery stenosis with a gradient of 25 mm Hg at 24 hours', 40 mmHg at one month's, and 64 mmHg at 6 months' follow-up. There were no cases of late embolization, aortic obstruction, late hemolysis, infective endocarditis, or death.Conclusion: Transcatheter PDA closure with the ADO was safe and effective, with a high success rate at long-term follow-up.

  2. Nozzle dam having a unitary plug

    Science.gov (United States)

    Veronesi, Luciano; Wepfer, Robert M.

    1992-01-01

    Apparatus for sealing the primary-side coolant flow nozzles of a nuclear steam generator. The steam generator has relatively small diameter manway openings for providing access to the interior of the steam generator including the inside surface of each nozzle, the manway openings having a diameter substantially less than the inside diameter of each nozzle. The apparatus includes a bracket having an outside surface for matingly sealingly engaging the inside surface of the nozzle. The bracket also has a plurality of openings longitudinally therethrough and a plurality of slots transversely therein in communication with each opening. A plurality of unitary plugs sized to pass through the manway opening are matingly sealingly disposed in each opening of the bracket for sealingly plugging each opening. Each plug includes a plurality of arms operable to engage the slots of the bracket for connecting each plug to the bracket, so that the nozzle is sealed as the plugs seal the openings and are connected to the bracket.

  3. A molecular plug-socket connector.

    Science.gov (United States)

    Rogez, Guillaume; Ribera, Belén Ferrer; Credi, Alberto; Ballardini, Roberto; Gandolfi, Maria Teresa; Balzani, Vincenzo; Liu, Yi; Northrop, Brian H; Stoddart, J Fraser

    2007-04-18

    A monocationic plug-socket connector that is composed, at the molecular level, of three components, (1) a secondary dialkylammonium center (CH2NH2+CH2), which can play the role of a plug toward dibenzo[24]crown-8 (DB24C8), (2) a rigid and conducting biphenyl spacer, and (3) 1,4-benzo-1,5-naphtho[36]crown-10 (BN36C10), capable of playing the role of a socket toward a 4,4'-bipyridinium dicationic plug, was synthesized and displays the ability to act as a plug-socket connector. The fluorescent signal changes associated with the 1,5-dioxynaphthalene unit of its BN36C10 portion were monitored to investigate the association of this plug-socket connector with the complementary socket and plug compounds. The results indicate that (1) the CH2NH2+CH2 part of the molecular connector can thread DB24C8 in a trivial manner and (2) the BN36C10 ring of the connector can be threaded by a 1,1'-dioctyl-4,4'-bipyridinium ion only after the CH2NH2+CH2 site is occupied by a DB24C8 ring. The two connections of the three-component assembly are shown to be controlled reversibly by acid/base and red/ox external inputs, respectively. The results obtained represent a key step for the design and construction of a self-assembling supramolecular system in which the molecular electron source can be connected to the molecular electron drain by a molecular elongation cable. PMID:17388589

  4. Quasi-Porous Plug With Vortex Chamber

    Science.gov (United States)

    Walsh, J. V.

    1985-01-01

    Pressure-letdown valve combines quasi-porous-plug and vortex-chamber in one controllable unit. Valve useful in fossil-energy plants for reducing pressures in such erosive two-phase process streams as steam/water, coal slurries, or combustion gases with entrained particles. Quasi-Porous Plug consists of plenums separated by perforated plates. Number or size of perforations increases with each succeeding stage to compensate for expansion. In Vortex Chamber, control flow varies to control swirl and therefore difference between inlet and outlet pressures.

  5. Plug-in hybrid electric vehicle R&D plan

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2007-06-01

    FCVT, in consultation with industry and other appropriate DOE offices, developed the Draft Plug-In Hybrid Electric Vehicle R&D Plan to accelerate the development and deployment of technologies critical for plug-in hybrid vehicles.

  6. Society for Vascular Medicine

    Science.gov (United States)

    ... and find out! Patient Information Pages from Vascular Medicine August 2016 The Vascular Laboratory More info for ... Learn more. Trending Now: Hot Topics in Vascular Medicine Video Series Fibromuscular Dysplasia (FMD) with Drs. Jeffrey ...

  7. Reliability of transthoracic echocardiography in estimating the size of Amplatzer septal occluder and guiding percutaneous closure of atrial septal defects

    Institute of Scientific and Technical Information of China (English)

    LI Gui-shuang; KONG Guang-ming; JI Qiu-shang; LI Ji-fu; CHEN Yu-guo; YOU Bei-an; ZHANG Yun

    2008-01-01

    Background In China,transthoracic echocardiography(TTE)is popularly used for pre-intervention examination for atrial septal defect(ASD)and for guiding ASD closure.However,the ability to determine ASD size and the safety and efficacy of TTE for guiding ASD closure still has not been widely accepted This study aimed to evaluate the efficacy and safety of TTE used before,during and after transcatheter ASD closure with Amplatzer septal occluders(ASO).Methods Sixty-eight subjects(15 men and 53 women;mean age(33.7±17.3)years)were enrolled.TTE was used to measure the diameters and guide transcatheter closure of ASD.The ASD was examined by long-axis view,basal short-axis view,apical four-chamber view and the subcostal view to observe position.diameter and reIation with neighbouring structures.The largest diameter was selected as the reference diameter.Patients were divided into 3 groups according to the ASD reference diameter:22 subjects with ASD diameter 4-14 mm(group A):21 subjects with ASD diameter 15-20 mm(group B);and 25 subjects with ASD diameter 21-33 mm(group C).Results ASD was occluded successfully in groups A and B.In group C.occlusion failed in 2 cases;1 case remained with a 3-mm residual shunt sustained untiI 6-month follow-up.However,at 6-month follow-up,no case of thromboembolism,ASO dislocation or death occurred in the three groups.The diameter of ASD measured bv TTE could accurately predict the ASO size that could successfully occlude the ASD.especially in patients with ASD<20 mm.The ASD diameter measured by TTE correlated well with ASO size(r=0.925,P<0.001:r=0.976,P<0.001;r=0.929,P<0.001 respectively).Conclusions ASD diameter measured by TTE can accurately estimate the size of the ASO needed for successful closure of ASD.The larger the ASD,the much larger the ASo needed.TTE is a satisfactory guiding imaging tool for ASD closure.

  8. eBooks & SFX Plug-Ins

    OpenAIRE

    Overkamp, I.

    2009-01-01

    The presentations shortly summarizes how the MPG-wide eBook subscriptions are integrated into the MPG/SFX service menu. The current implementation uses the SFX Plug-In feature to request holding information from the MPG eBooks catalog on-the-fly.

  9. An optimal design for millimeter-wide facture plugging zone

    Directory of Open Access Journals (Sweden)

    Yili Kang

    2015-01-01

    Full Text Available Lost circulation control in millimeter-wide fractures has been a challenge in well drilling all the time. Low pressure-bearing capacity of a plugging zone will result in excessive consumption of lost circulation materials (LCMs and extra down time. In this study, laboratory experiments were conducted on the plugging of millimeter-wide fractures to evaluate the plugging effects of different types of LCM including rigid granules, elastic particles and fiber. Maximum plugging pressure, total loss volume before sealing and plugging time were taken as the evaluation index of the LCM plugging effect. According to the experimental results, the synergistic plugging mechanisms of different LCM combinations were also analyzed. Experimental results showed that the total loss volume of the plugging zone formed by rigid and elastic particle combination was generally greater than 400 mL, and the maximum plugging pressure of the plugging zone formed by elastic particle and fiber combination was generally less than 6 MPa. In contrast, the plugging zone formed by the combination of the three types of LCMs has the maximum plugging pressure of up to 13 MPa and total loss volume before sealing of 75 mL. In the synergistic plugging process, rigid granules form a frame with high pressure-bearing capacity in the narrower parts of the fractures; elastic particles generate elastic force through elastic deformation to increase the friction between a fracture and a plugging zone to make the plugging zone more stable; fibers filling in the pore space between the particles increase the tightness and integrity of the plugging zone. The experimental results can provide guidance for the optimal design of LCMs used in the field.

  10. Bond strength of cementitious borehole plugs in welded tuff

    International Nuclear Information System (INIS)

    Axial loads on plugs or seals in an underground repository due to gas, water pressures and temperature changes induced subsequent to waste and plug emplacement lead to shear stresses at the plug/rock contact. Therefore, the bond between the plug and rock is a critical element for the design and effectiveness of plugs in boreholes, shafts or tunnels. This study includes a systematic investigation of the bond strength of cementitious borehole plugs in welded tuff. Analytical and numerical analysis of borehole plug-rock stress transfer mechanics is performed. The interface strength and deformation are studied as a function of Young's modulus ratio of plug and rock, plug length and rock cylinder outside-to-inside radius ratio. The tensile stresses in and near an axially loaded plug are analyzed. The frictional interface strength of an axially loaded borehole plug, the effect of axial stress and lateral external stress, and thermal effects are also analyzed. Implications for plug design are discussed. The main conclusion is a strong recommendation to design friction plugs in shafts, drifts, tunnels or boreholes with a minimum length to diameter ratio of four. Such a geometrical design will reduce tensile stresses in the plug and in the host rock to a level which should minimize the risk of long-term deterioration caused by excessive tensile stresses. Push-out tests have been used to determine the bond strength by applying an axial load to cement plugs emplaced in boreholes in welded tuff cylinders. A total of 130 push-out tests have been performed as a function of borehole size, plug length, temperature, and degree of saturation of the host tuff. The use of four different borehole radii enables evaluation of size effects. 119 refs., 42 figs., 20 tabs

  11. Application of Amplatzer vascular occluder in hepatic artery closure as a method of treatment of high-flow arterioportal fistula before liver transplantation

    OpenAIRE

    Poncyljusz, Wojciech; Pauli, Wojciech

    2012-01-01

    Summary Background: Arterioportal fistula (APF) is an abnormal, direct connection between hepatic artery or its branch and the portal vein. Fistula can be acquired or, rarely, congenital. One of the acquired causes of fistula is a liver biopsy. Patients with liver cirrhosis are particularly vulnerable to its development due to the large number of performed biopsies. APF increases mortality and morbidity of liver transplantation procedure and may be a contraindication to it. The authors presen...

  12. Risk and countermeasure of ice-plug technology application

    International Nuclear Information System (INIS)

    The application of ice-plug technology can realize the system isolation online. In order to know the inherent laws which the ice-plug forms, and reduces the application risk of ice-plug technology, we carried out many simulation experiments according to the operating characteristics of some components of the secondary loop of Qinshan nuclear power plant, and obtained many different parameters of the ice-plug forming. And the stress test, the crack detection and the metal microstructure analysis were also carried out for the metal pipeline which has been frozen. According to the analysis of ice-plug principle and the simulation test results, we found that we can reduce the application risk of ice-plug technology, and enhance the ice-plug application more scientifically and reliably by adjusting the freezing speed, reducing the chilling temperature according to the rules of pipeline material in different stages during ice-plug forming. Meanwhile, making use of each kind of risk indicators of ice-plug forming process, countermeasures and the method to control ice-plug risk are proposed. Finally, the article introduced some concrete procedures how to control ice-plug application risk in Qinshan nuclear power plant. (author)

  13. Risk and countermeasure of ice-plug technology application

    International Nuclear Information System (INIS)

    The application of the ice-plug technology can realize the system isolation online. In order to know the inherent laws which the Ice-plug forms, reduces the application risk of ice-plug technology, we have done many simulation operating experiments according to some turbine island system operating characteristic of Qinshan nuclear power plant, obtained many different parameters of the ice-plug forming. And do the stress test, the crack detection and the metal microstructure analysis to the metal pipeline which has been frozen. According to analysis of the ice-plug principle and the simulation test result, we found that we can improve the ice-plug technology application risk, and enhance the ice-plug application more scientific and reliable by adjusting freezing speed, reducing the chilling temperature according to the rules of the pipeline material in different stages during ice-plug forming. Meanwhile use the each kind of risk indicator of ice-plug forming process, proposed countermeasure,the method of the control ice-plug risk. Finally, the article introduced some concrete procedures how to control ice-plug application risk in Qinshan nuclear power plant. (authors)

  14. Non-rotating cementing plug with molded inserts

    International Nuclear Information System (INIS)

    This patent describes an anti-rotation plug set for use with cementing equipment having an insert seat therein, the anti-rotation plug set and the cementing equipment for use in cementing a string of casing into a well bore. It comprises an upper plug including: a non-metallic body member having a plurality of teeth integrally formed on the lower end thereof and an elastomeric covering thereon having, in turn, wipers which engage the interior of the string of casing; and a lower plug including: a non-metallic body member having a bore therethrough, having teeth integrally formed on the upper end thereof which mate with the teeth integrally formed on the lower end of the nonmetallic body member of the upper plug when the upper plug engages the lower plugs, having teeth integrally formed on the lower end thereof, having an insert member in a portion of the bore through the non-metallic body member, and the cementing equipment comprising: an insert seat having teeth thereon which mate with the integrally formed teeth on the lower end of the non-metallic body member of the lower plug of the anti-rotation plug set when the lower plug of the anti-rotation plug set engages the cementing equipment during the cementing of the string of casing into a well bore

  15. Steam tests of Alloy 600 and Alloy 690 mechanical plugs

    International Nuclear Information System (INIS)

    In 1988-89, randomly selected heats of Inconel 600 TT plugs were laboratory tested to determine the extent and distribution of carbide precipitation in the microstructure and their resistance to primary water stress corrosion cracking (PWSCC) in a 400 C doped steam autoclave. Early results indicated a ranking could be established between microstructure and PWSCC potential. Corrosion tests were extended to include Alloy 690 plugs after a top plug release occurred due to circumferential cracking above the expander. Destructive examination of pulled plugs confirmed the accuracy of the laboratory results which showed corrosion resistance can be correlated with the density of intergranular carbides and the doped steam test method did provide an accelerated method for assessing the relative PWSCC of mechanical plugs. To date, 70 Inconel 690 plugs, representing 17 heat treatment lots, have been tested and all plugs remain crack-free after 1000 hour exposure in doped steam. 4 figs

  16. CDF End Plug calorimeter Upgrade Project

    International Nuclear Information System (INIS)

    We report on the status of the CDF End Plug Upgrade Project. In this project, the CDF calorimeters in the end plug and the forward regions will be replaced by a single scintillator based calorimeter. After an extensive R ampersand D effort on the tile/fiber calorimetry, we have now advanced to a construction phase. We review the results of the R ampersand D leading to the final design of the calorimeters and the development of tooling devised for this project. The quality control program of the production of the electromagnetic and hadronic calorimeters is described. A shower maximum detector for the measurement of the shower centroid and the shower profile of electrons, γ and π0 has been designed. Its performance requirements, R ampersand D results and mechanical design are discussed

  17. Plugging pig reduces line maintenance, repair costs

    Energy Technology Data Exchange (ETDEWEB)

    1976-05-01

    A relatively new technique involving the use of plugging pigs to seal-off thruput on liquids lines was used by Ashland Pipe Line Co. during consecutive maintenance and repair projects on a crude trunkline in Illinois. Following completion, cost of the two operations was estimated at about two-thirds of that for similar projects using conventional line-plugging equipment. The pigs are produced by International Pipeline Equipment Co. (IPE) and are inserted into the line from the standard cleaning and batching, pig-launching equipment installed on the system. Ashland used one of the special pigs during reconditioning of a gate valve at its Patoka terminal and then pumped it downstream to seal the line at the site of a damage repair project. The service is provided by Advance Valve Installations, Inc.

  18. Borehole plugging by hydrothermal transport. Final report

    International Nuclear Information System (INIS)

    Calcium silicate--and aluminosilicate--compositions based on mixtures of fine grained quartz with various cements or calcium silicate compounds have been investigated under hydrothermal conditions in the temperature range 110-2500C and pressure range 1,000-10,000 psi, pressures which are always in excess of that required to maintain liquid H2O, and approximate the confining pressures which might be anticipated in deep boreholes. All silicate cement combinations investigated produce materials having adequate strength after reaction times of 1 day or longer. The calcium aluminate cement was also adequate with respect to strength but would need to be investigated more extensively for overall properties because of its highly reactive chemistry. The mini-rock cylinder-cement plug hydrothermal experiments in both limestone and sandstone resulted in reasonable magnitudes of bonding strength. The typical shear strength of a hydrothermally treated cement-sandstone plug is 1030 psi, and the compressive strength of the extruded cement plug is 9550 psi. Reactions having a potential for producing calcium carbonate plugs in holes drilled in carbonate rocks were studied. It should be noted that most cements are calcium silicate systems and are chemically compatible with the CaCO3 and CaMg(CO3)2 in the rock walls of the hole. A side benefit from this research is some insight into the suitability of massive carbonate rocks as disposal sites. Carbonate rocks by themselves are highly impermeable, have low exchange capacity, and a low water content--all properties that are desirable in the storage medium. A major drawback is the presence of secondary permeability in the form of solutionally modified joints, fractures, and bedding planes

  19. Ice plugging of pipes using liquid nitrogen

    International Nuclear Information System (INIS)

    This report presents a study on the ice plugging of pipe using liquid nitrogen, and is based on a literature review and on discussions with individuals who use the technique. Emphasis is placed on ferritic alloys, primarily carbon steels, in pipe sized up to 60 cm in diameter and on austenitic stainless steels in pipe sizes up to 30 cm in diameter. This technique is frequently used for leak testing in nuclear facilities

  20. Transcatheter Closure of Atrial Septal Defect with Amplatzer Septal Occluder in Adults: Immediate, Short, and Intermediate-Term Results

    Directory of Open Access Journals (Sweden)

    Majid Dehghani

    2011-05-01

    Full Text Available Background: The transcatheter closure of the atrial septal defect (ASD has become an alternative technique to surgical procedures. The aim of this study was to assess the immediate, short, and intermediate-term results of the transcatheter closure of the secundum ASD with the Amplatzer Septal Occluder (ASO in adult Iranian patients.Methods: Between December 2004 and July 2008, the transcatheter closure of the ASD using the ASO was attempted in 58consecutive, adult patients. The mean age of the patients was 37.1 ± 12.7 years (range = 19 - 75 years.All the procedures were performed under local anesthesia with transthoracic or transesophageal echocardiography and fluoroscopic guidance. The stretched diameter of the ASD was determined with a balloon sizing catheter, and device selection was based on and matched to the stretched diameter of the septal defect.Transthoracic echocardiography was performed immediately after the release of the device and before discharge.Further follow-up at one month, six months, and yearly thereafter included physical examination, electrocardiography, andtransthoracic echocardiography.Results: The mean ASD diameter, as measured by esophageal echocardiography, was 24.8 ± 5.4 mm (range = 13 - 34 mm.The mean stretched diameter, as measured by the balloon catheter, was 27.1 ± 6.4 mm (range = 12.5 - 39 mm. Deploymentof the ASO was successful in 52 (89.6% patients and failed in 6 (10.4%. Four patients experienced severe complications,1 had tamponade requiring drainage, 2 had device embolization to the left atrium and right ventricular outflow tract, and 1 had late wire fracture (surgical removal and repair of the ASD. The position of two large devices (34 mm and 36 mm was considered unsuitable and unstable after implantation and resulted in the removal of these devices.Minor complications included transient complete atrioventricular block in 1 patient, paroxysmal supra tachycardia in 3 patients, atrial flutter in 1 patient

  1. Remote Handling behind port plug in ITER

    International Nuclear Information System (INIS)

    Different Test Blanket Modules (TBM) will be used in succession in the same equatorial ports of ITER. The remote handling operations for connection/disconnection of an interface between the port plug of the EU-HCPB-TBM and the port cell equipment are investigated with the goal to reach a quick and simple TBM exchange procedure. This paper describes the operations and systems which are required for connection of the TBM to its supply lines at this interface. The interface is located inside the free space of the port plug flange between the port plug shield and the bioshield of the port cell behind. The approach of the operation place is only available through a narrow gate in the bioshield opened temporarily during maintenance periods. This gate limits the dimensions of the whole system and its tools. The current design of the EU-HCPB-TBM foresees up to 9 supply lines which have to be connected inside the free space of one half of the port plug flange. The connection operations require positioning and adjustment of the tools for each pipe separately. Despite the strict circumstances it is still possible to find such an industrial jointed-arm robot with sufficient payload, which can penetrate into the working area. A mechanical system is necessary to move the robot from its storing place in the hot cell to the port plug on 6 m distance. Each operation requires different end-of-arm tools. The most special one is a pipe positioner tool, which can position and pull the pipe ends to each other and align the tool before welding and hold them in proper position during the welding process. Weld seams can be made by orbital welding tool. The pipe positioner tool has to provide place for welding tool. Using of inbore tool is impossible because pipes have no open ends where the tool could leave it. Orbital tool must be modified to meet requirements of remote handling because it is designed for human handling. The coolant is helium, so for eliminating the leak of helium it is

  2. Design progress on ITER port plug test facility

    International Nuclear Information System (INIS)

    To achieve the overall ITER machine availability target, the availability of diagnostics and heating port plugs shall be as high as 99.5%. To fulfill these requirements, it is mandatory to test the port plugs at operating temperature before installation on the machine and after refurbishment. The ITER port plug test facility (PPTF) provides the possibility to test upper and equatorial port plugs before installation on the machine. The port plug test facility is composed of several test stands. These test stands are first used in the domestic agencies and on the ITER Organization site to test the port plugs at the end of manufacturing. Two of these stands are installed later in the ITER hot cell facility to test the port plugs after refurbishment. The port plugs to be tested are the Ion Cyclotron (IC) heating and current drive antennas, Electron Cyclotron (EC) heating and current drive launchers, diagnostics and test blanket modules port plugs. Test stands shall be capable to perform environmental and functional tests. The test stands are composed of one vacuum tank (3.3 m in diameter, 5.6 m long) and the associated heating, vacuum and control systems. The vacuum tank shall achieve an ultimate pressure of 1 × 10−5 Pa at 100 °C containing a port plug. The heating system shall provide water at 240 °C and 4.4 MPa to heat up the port plugs. Openings are provided on the back of the vacuum tank to insert probes for the functional tests. This paper describes the tests to be performed on the port plugs and the conceptual design of the port plug test facility. The configuration of the standalone test stands and the integration in the hot cell facility are presented.

  3. Results from the Bell Canyon borehole plugging test

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, C. L.

    1980-01-01

    The BHP is an integrated program involving consequence assessment and plug performance calculations, materials evaluation, instrumentation development and field testing, and interfaces directly with other WIPP-related activities. This paper describes an in situ test conducted under the BHP Field Test Task. The Bell Canyon Test was conducted to evaluate candidate grout plugging mixes and plug emplacement techniques, and to assess plug performance under in-situ cure conditions. Laboratory testing of the brine-grout/rock combination revealed an adverse reaction between the brine-grout and the anhydrite. This discovery permitted a timely change to an additional laboratory compatibility testing program with an alternate fresh-water mix to permit maintenance of the test schedule with little delay. While cement emplacement technology is generally adequate to satisfy repository plugging requirements, plug compatibility with the host rock must be carefully assessed for each repository site. Generally accepted laboratory cement-testing techniques need to include flow characteristics and geochemical stability.

  4. Smart grid agent: Plug-in electric vehicle

    OpenAIRE

    Dallinger, David; Link, Jochen; Büttner, Markus

    2013-01-01

    This study describes a method for programming a plug-in electric vehicle agent that can be used in power system models and in embedded systems implemented in real plug-in electric vehicles. Implementing the software in real-life applications and in simulation tools enables research with a high degree of detail and practical relevance. Agent-based programming, therefore, is an important tool for investigating the future power system. To demonstrate the plug-in electric vehicle agent behavior, ...

  5. Palliative embolisation for intrapulmonary shunting in lepidic predominant adenocarcinoma of the lung

    Directory of Open Access Journals (Sweden)

    Joanne Yue-Ai Tan

    2015-01-01

    Full Text Available Lepidic predominant adenocarcinoma (LPA (formerly known as bronchioalveolar carcinoma has rarely been reported to cause refractory hypoxia with intrapulmonary shunting [1–7]. We describe a case who underwent the palliative strategy of intravascular right lower pulmonary artery embolisation with an 18 mm Amplatzer II vascular plug to reduce intrapulmonary shunting. This is the first report we are aware of using this minimally invasive procedure to treat this condition.

  6. Residual solidification stress in plug welds

    International Nuclear Information System (INIS)

    Installation of the plugs in Steam Generators and Heat Exchangers is performed using GTAW process with filler metal. During the cooling phase of the weld puddle residual stresses will be generated in the weld. The residual stresses together with the stresses from the primary and secondary loads will define the total stress in the weld. The level of total stress is important for the reliability of the plug joints. Typically, the welding procedures prescribe a range of values for each welding parameters, therefore the welder has the option to select a relative wide range of combinations of parameters based on test results, welding position, experience, etc. Manual welding processes are more susceptible to larger variation of the heat input than the automatic welding processes. The combination of the welding parameters may be controlled by a generic parameter called welding heat input. The net effect of the heat input is to control the energy introduced by an arc at weld joint such that adequate weld puddle is produced. The heat input along with the thermal properties of the materials control the temperature distribution in the welded joint. Ultimately, the response of the structure to the thermal loads resulted from the non-uniform distribution of temperature is a non-uniform distribution of the plastic strains that results in residual stresses. This paper presents the effect of variation of welding heat input on distribution of residual stresses. Finite element method is used to simulate the welding process for various heat inputs that may be encountered during plug welding. The analysis is performed in two steps. In the first step a thermal transient analysis is performed in which the temperature distribution due to a moving heat source is obtained. The resulting thermal field is used as input data for structural analysis. It is shown that the extent of residual stresses in the weld joint is affected by the energy used to produce the weld and can be related to the

  7. COMP: Comparing Ontology Matching Plug-in

    Czech Academy of Sciences Publication Activity Database

    Tyl, Pavel; Loufek, J.

    Los Alamitos : IEEE Computer Society, 2009 - (Abraham, A.; Húsek, D.; Snášel, V.), s. 44-49 ISBN 978-0-7695-3821-1. [NWeSP 2009. International Conference on Next Generation Web Services Practices /5./. Prague (CZ), 09.11.2009-11.09.2009] R&D Projects: GA MŠk 1M0554 Institutional research plan: CEZ:AV0Z10300504 Keywords : matching * ontologie * plug-in * Protégé Subject RIV: IN - Informatics, Computer Science

  8. Testing and plugging power plant heat exchangers

    Energy Technology Data Exchange (ETDEWEB)

    Sutor, F. [Expando Seal Tools, Inc., Montgomeryville, PA (United States)

    1994-12-31

    Heat Exchanger tubes fail for any number of reasons including but certainly not limited to the cumulative effects of corrosion, erosion, thermal stress and fatigue. This presentation will attempt to identify the most common techniques for determining which tubes are leaking and then introduce the products in use to plug the leaking tubes. For the sake of time I will limit the scope of this presentation to include feedwater heaters and secondary system heat exchangers such as Hydrogen Coolers, Lube Oil Coolers, and nuclear Component Cooling Water, Emergency Cooling Water, Regenerative Heat Recovery heat exchangers.

  9. Knowledge-Based System to Support Plug Load Management

    Data.gov (United States)

    National Aeronautics and Space Administration — Electrical plug loads comprise an increasingly larger share of building energy consumption as improvements have been made to Heating, Ventilation, and Air...

  10. Effects of Different Progesterone Plugs on Estrous Control in Ewe

    Institute of Scientific and Technical Information of China (English)

    WU Hongda

    2009-01-01

    In breeding season and non-breeding season, the effects of three kinds of progesterone plugs on estrous control in ewes were studied. Meanwhile, the advantages and the disadvantages of the progesterone plugs were analyzed. The results showed that there were no significant difference among three progesterone plugs on modulating the ewes' estrus and pregnancy, and affecting estrous rate and fecundation rate (P>0.05). It was observed that the progesterone plug produced by Animal Husbandry Research Center of Heilongjiang Academy of Agricultural Sciences could modulate the ewes' estrus and pregnancy effectively, and the low cost and convenience in operation made it popularize in the reproducation of sheep widely.

  11. Collagen vascular disease

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/001223.htm Collagen vascular disease To use the sharing features on this page, ... were previously said to have "connective tissue" or "collagen vascular" disease. We now have names for many of many ...

  12. Heart and vascular services

    Science.gov (United States)

    ... branch of medicine that focuses on the cardiovascular system. ... Circulatory system; Vascular system; Cardiovascular system ... to diagnose, monitor or treat diseases of the circulatory and vascular system include: Cardiac CT for calcium scoring Cardiac MRI ...

  13. Deep Space Habitat Wireless Smart Plug

    Science.gov (United States)

    Morgan, Joseph A.; Porter, Jay; Rojdev, Kristina; Carrejo, Daniel B.; Colozza, Anthony J.

    2014-01-01

    NASA has been interested in technology development for deep space exploration, and one avenue of developing these technologies is via the eXploration Habitat (X-Hab) Academic Innovation Challenge. In 2013, NASA's Deep Space Habitat (DSH) project was in need of sensors that could monitor the power consumption of various devices in the habitat with added capability to control the power to these devices for load shedding in emergency situations. Texas A&M University's Electronic Systems Engineering Technology Program (ESET) in conjunction with their Mobile Integrated Solutions Laboratory (MISL) accepted this challenge, and over the course of 2013, several undergraduate students in a Capstone design course developed five wireless DC Smart Plugs for NASA. The wireless DC Smart Plugs developed by Texas A&M in conjunction with NASA's Deep Space Habitat team is a first step in developing wireless instrumentation for future flight hardware. This paper will further discuss the X-Hab challenge and requirements set out by NASA, the detailed design and testing performed by Texas A&M, challenges faced by the team and lessons learned, and potential future work on this design.

  14. How to Prevent Vascular Disease

    Science.gov (United States)

    ... our CEO Board of Directors Scientific Advisory Board History of Vascular Cures Impact Contact Us Vascular Disease What is Vascular Disease? Education and Awareness Vascular Diseases Abdominal Aortic Aneurysm Aortic ...

  15. Hybrid and Plug-In Electric Vehicles (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2014-05-01

    Hybrid and plug-in electric vehicles use electricity as their primary fuel or to improve the efficiency of conventional vehicle designs. These vehicles can be divided into three categories: hybrid electric vehicles (HEVs), plug-in hybrid electric vehicles (PHEVs), all-electric vehicles (EVs). Together, they have great potential to cut U.S. petroleum use and vehicle emissions.

  16. Plug-in hybrid electric vehicles in dynamical energy markets

    NARCIS (Netherlands)

    Kessels, J.T.B.A.; Bosch, P.P.J. van den

    2008-01-01

    The plug-in hybrid electric vehicle allows vehicle propulsion from multiple internal power sources. Electric energy from the grid can be utilized by means of the plug-in connection. An on-line energy management (EM) strategy is proposed to minimize the costs for taking energy from each power source.

  17. The Losing Battle against Plug-and-Chug

    Science.gov (United States)

    Kortemeyer, Gerd

    2016-01-01

    I think most physics teachers would agree that two important components of a proper solution to a numerical physics problem are to first figure out a final symbolic solution and to only plug in numbers in the end. However, in spite of our best efforts, this is not what the majority of students is actually doing. Instead, they tend to plug numbers…

  18. "Plug-In" for More Active Online Learning.

    Science.gov (United States)

    Tuttle, Harry G.

    1997-01-01

    Discusses plug-ins, software programs that connect to an World Wide Web browser and enhance its functionality. Highlights finding the software; downloading and using plug-ins; and educational applications, including the document viewer, real-time chat, multimedia, map viewer, spelling checker, news network, sound and video, and real-time…

  19. Eddy current inspection of steam generator tubing plugs

    International Nuclear Information System (INIS)

    In response to the issues raised regarding the integrity of nuclear steam generator tubing plugs manufactured from certain heats of Inconel 600, Westinghouse engineers have developed, qualified and implemented an eddy current inspection system for the in-place assessment of these plugs. The heart of the system is a robotic and effector which delivers an eddy current sensor through the reduced diameter of the plug expander and actuates the coil to physical contact with the expanded inside bore of the plug. Once deployed, the eddy current sensor is rotated along a helical path to produce a detailed scan of the plug surface above the final position of the expander. This testing produces an isometric display of degradation due to primary water stress corrosion cracking, on the inside surface of the plug. To date, successful inspections have been conducted at two nuclear units with two different robotic delivery systems. While designed specifically for mechanical plugs with a bottle bore cavity, the inspection system can also be used for expanded straight bore plugs. Details of the inspection system along with a discussion of qualification activities and actual field results are presented in this paper

  20. 662-E solid waste silo-plug lifting analysis

    Energy Technology Data Exchange (ETDEWEB)

    Mertz, G.E.

    1993-03-01

    The Intermediate Level Tritium Vault No. 1, 662-E, Cell No. 1 contains 140 waste silos. Each silo is approximately 25 feet deep, 30 inches in diameter at the top and covered by a reinforced concrete plug. Two No. 4 reinforcing bars project from the top of each plug for lifting. During lifting operations, the 1.5 inch concrete cover over the lifting bars spelled off 16% of the silo plugs. The No. 4 reinforcing bars were also distorted on many of the silo plugs. Thirteen of the plugs have been repaired to date. The existing silo plug lifting bars have a safe working load of 480 pounds per plug, which is less than 1/3 of the dead weight of the silo plug. The safe working load was calculated using the minimum design factor of 3 based on the yield strength or 5 based on the ultimate strength of the material, as per the Savannah River Site Hoisting and Rigging Manual. The existing design calculations were reviewed, and the following items are noted: (1) Adequate concrete cover was not provided over the horizontal portion of the lifting bars. (2) The lifting bars were allowed to yield in bending, which violates the requirements of the Savannah River Site Hoisting and Rigging Manual. (3) The ultimate strain of the lifting bars would be exceeded before the calculated ultimate strength was achieved. Alternative lifting devices are also identified.

  1. End plugging of a linear theta pinch by pulsed mirrors

    International Nuclear Information System (INIS)

    It is shown that by suitably pulsing a magnetic mirror end plug of a linear theta pinch, one can substantially reduce the end loss. A system consisting of a linear pinch with sequentially pulsed multimirror end plugs is proposed which shows promise of fusion feasibility. (author)

  2. Numerical modeling of an end-plugged theta pinch

    International Nuclear Information System (INIS)

    Analytical and numerical studies of an end-plugged theta pinch are described. The analytical model treats the ablated plug plasma in the quasi-static limit where radiation losses balance energy flowing from the main plasma. This model is used to calculate the enhancement in energy confinement due to an ablating end plug for various plug species. The numerical model employs a one-dimensional, time-dependent magnetohydro-dynamic code. Results of calculations simulating the Scylla IV-P end-plugged theta pinch experiment are presented. The calculations achieve good agreement with the observed decay time of the energy line density. Moreover, the observed tendency toward longer decay times at lower atomic number is also predicted. However, certain notable discrepancies are found. For Si plugs, the calculations indicate a somewhat longer decay time than observed with SiO2 plugs. In addition, an axial compression wave driven by plug ablation causes the calculated energy line density to rise after 15 to 20 μsec which was not observed in the experiments. This is believed to be a feature of the one radial cell model which forbids axial wave dispersion; such dispersion would tend to mute the appearance of such waves. For fusion reactor scale plasma, the calculations predict that higher atomic number leads to negligible enhancements in confinement time

  3. California Statewide Plug-In Electric Vehicle Infrastructure Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Melaina, Marc; Helwig, Michael

    2014-05-01

    The California Statewide Plug-In Electric Vehicle Infrastructure Assessment conveys to interested parties the Energy Commission’s conclusions, recommendations, and intentions with respect to plug-in electric vehicle (PEV) infrastructure development. There are several relatively low-risk and high-priority electric vehicle supply equipment (EVSE) deployment options that will encourage PEV sales and

  4. Unbalanced-flow, fluid-mixing plug with metering capabilities

    Science.gov (United States)

    England, John Dwight (Inventor); Kelley, Anthony R. (Inventor); Van Buskirk, Paul D. (Inventor)

    2009-01-01

    A fluid mixer plug has holes formed therethrough such that a remaining portion is closed to fluid flow. The plug's inlet face defines a central circuit region and a ring-shaped region with the ring-shaped region including at least some of the plug's remaining portion so-closed to fluid flow. This remaining portion or closed region at each radius R of the ring shaped region satisfies a radius independent, flow-based relationship. Entry openings are defined in the plug's inlet face in correspondence with the holes. The entry openings define an open flow area at each radius of the ring-shaped region. The open flow area at each such radius satisfies the inverse of the flow-based relationship defining the closed regions of the plug.

  5. Development of sealing plug for sweep gas line

    International Nuclear Information System (INIS)

    On the irradiation capsule for neutron irradiation test of the tritium breeder, the sealing plug is necessary to prevent a leak of tritium gas when the tritium breeder is picked up from the irradiation capsule after irradiation test. However, the general valve and plug cannot apply to sealing of the sweep gas line because of the following factors, the neutron irradiation effect, limited space in the irradiation capsule, high sealing efficiency, simple method and operation for control. Therefore, the sealing plug for sweep gas line has to be developed. This paper reports the development of the sealing plug for sweep gas line and the operating procedure of the sealing plug in the irradiation capsule. (author)

  6. Mitigation of Syngas Cooler Plugging and Fouling

    Energy Technology Data Exchange (ETDEWEB)

    Bockelie, Michael J. [Reaction Engineering International, Salt Lake City, UT (United States)

    2015-06-29

    This Final Report summarizes research performed to develop a technology to mitigate the plugging and fouling that occurs in the syngas cooler used in many Integrated Gasification Combined Cycle (IGCC) plants. The syngas cooler is a firetube heat exchanger located downstream of the gasifier. It offers high thermal efficiency, but its’ reliability has generally been lower than other process equipment in the gasification island. The buildup of ash deposits that form on the fireside surfaces in the syngas cooler (i.e., fouling) lead to reduced equipment life and increased maintenance costs. Our approach to address this problem is that fouling of the syngas cooler cannot be eliminated, but it can be better managed. The research program was funded by DOE using two budget periods: Budget Period 1 (BP1) and Budget Period 2 (BP2). The project used a combination of laboratory scale experiments, analysis of syngas cooler deposits, modeling and guidance from industry to develop a better understanding of fouling mechanisms and to develop and evaluate strategies to mitigate syngas cooler fouling and thereby improve syngas cooler performance. The work effort in BP 1 and BP 2 focused on developing a better understanding of the mechanisms that lead to syngas cooler plugging and fouling and investigating promising concepts to mitigate syngas cooler plugging and fouling. The work effort focused on the following: • analysis of syngas cooler deposits and fuels provided by an IGCC plant collaborating with this project; • performing Jet cleaning tests in the University of Utah Laminar Entrained Flow Reactor to determine the bond strength between an ash deposit to a metal plate, as well as implementing planned equipment modifications to the University of Utah Laminar Entrained Flow Reactor and the one ton per day, pressurized Pilot Scale Gasifier; • performing Computational Fluid Dynamic modeling of industrially relevant syngas cooler configurations to develop a better

  7. Plugging criteria for WWER SG tubes

    Energy Technology Data Exchange (ETDEWEB)

    Papp, L.; Wilam, M. [Vitkovice NPP Services (Switzerland); Herman, M. [Vuje, Trnava (Slovakia)

    1997-12-31

    At operated Czech and Slovak nuclear power plants the 80 % criteria for crack or other bulk defect depth is used for steam generator heat exchanging tubes plugging. This criteria was accepted as the recommendation of designer of WWER steam generators. Verification of this criteria was the objective of experimental program performed by Vitkovice, J.S.C., UJV Rez, J.S.C. and Vuje Trnava, J.S.C .. Within this program the following factors were studied: (1) Influence of secondary water chemistry on defects initiation and propagation, (2) Statistical evaluation of corrosion defects progression at operated SG, and (3) Determination of critical pressure for tube rupture as a function of eddy current indications. In this presentation items (2) and (3) are considered.

  8. Welding nuclear reactor fuel rod end plugs

    International Nuclear Information System (INIS)

    Apparatus for applying a vacuum to a nuclear fuel rod cladding tube's interior through its open end while girth welding an inserted end plug to its other end. An airtight housing has an orifice with a seal which can hermetically engage the tube's open end. A vacuum hose has one end connected to the housing and the other end connected to a vacuum pump. A mechanized device which moves the housing to engage or disengage its seal with the tube's open end includes at least one arm having one end attached to the housing and the other end pivotally attached to a movable table; an arm rotating device to coaxially align the housing's orifice with the welding-positioned tube; and a table moving device to engage the seal of the coaxially aligned orifice with the tube's open end. (author)

  9. Welding nuclear reactor fuel rod end plugs

    International Nuclear Information System (INIS)

    Apparatus for applying a vacuum to a nuclear fuel rod cladding tube's interior through its open end while girth welding an inserted end plug to its other end. An airtight housing has an orifice with a seal which can hermetically engage the tube's open end. A vacuum hose has one end connected to the housing and the other end connected to a vacuum pump. A mechanized device moves the housing to engage or disengage its seal with the tube's open end. Preferably the mechanized device includes an arm having one end attached to the housing and the other end pivotally attached to a moveable table; an arm rotating device to coaxially align the housing's orifice with the welding-positioned tube; and a table moving device to engage the seal of the coaxially aligned orifice with the tube's open end

  10. Plugging criteria for WWER SG tubes

    International Nuclear Information System (INIS)

    At operated Czech and Slovak nuclear power plants the 80 % criteria for crack or other bulk defect depth is used for steam generator heat exchanging tubes plugging. This criteria was accepted as the recommendation of designer of WWER steam generators. Verification of this criteria was the objective of experimental program performed by Vitkovice, J.S.C., UJV Rez, J.S.C. and Vuje Trnava, J.S.C .. Within this program the following factors were studied: (1) Influence of secondary water chemistry on defects initiation and propagation, (2) Statistical evaluation of corrosion defects progression at operated SG, and (3) Determination of critical pressure for tube rupture as a function of eddy current indications. In this presentation items (2) and (3) are considered

  11. Strategies for Controlling Plug Loads. A Tool for Reducing Plug Loads in Commercial Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Torcellini, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bonnema, Eric [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sheppy, Michael [National Renewable Energy Lab. (NREL), Golden, CO (United States); Pless, Shanti [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-09-01

    Plug loads are often not considered as part of the energy savings measures in Commercial Buildings; however, they can account for up to 50% of the energy used in the building. These loads are numerous and often scattered throughout a building. Some of these loads are purchased by the owner and some designed into the building or the tenant finishes for a space. This document provides a strategy and a tool for minimizing these loads.

  12. Imaging Pediatric Vascular Lesions

    Science.gov (United States)

    Nguyen, Tuyet A.; Krakowski, Andrew C.; Naheedy, John H.; Kruk, Peter G.

    2015-01-01

    Vascular anomalies are commonly encountered in pediatric and dermatology practices. Most of these lesions are benign and easy to diagnose based on history and clinical exam alone. However, in some cases the diagnosis may not be clear. This may be of particular concern given that vascular anomalies may occasionally be associated with an underlying syndrome, congenital disease, or serious, life-threatening condition. Defining the type of vascular lesion early and correctly is particularly important to determine the optimal approach to management and treatment of each patient. The care of pediatric patients often requires collaboration from a multitude of specialties including pediatrics, dermatology, plastic surgery, radiology, ophthalmology, and neurology. Although early characterization of vascular lesions is important, consensus guidelines regarding the evaluation and imaging of vascular anomalies does not exist to date. Here, the authors provide an overview of pediatric vascular lesions, current classification systems for characterizing these lesions, the various imaging modalities available, and recommendations for appropriate imaging evaluation. PMID:26705446

  13. Imaging Pediatric Vascular Lesions.

    Science.gov (United States)

    Nguyen, Tuyet A; Krakowski, Andrew C; Naheedy, John H; Kruk, Peter G; Friedlander, Sheila Fallon

    2015-12-01

    Vascular anomalies are commonly encountered in pediatric and dermatology practices. Most of these lesions are benign and easy to diagnose based on history and clinical exam alone. However, in some cases the diagnosis may not be clear. This may be of particular concern given that vascular anomalies may occasionally be associated with an underlying syndrome, congenital disease, or serious, life-threatening condition. Defining the type of vascular lesion early and correctly is particularly important to determine the optimal approach to management and treatment of each patient. The care of pediatric patients often requires collaboration from a multitude of specialties including pediatrics, dermatology, plastic surgery, radiology, ophthalmology, and neurology. Although early characterization of vascular lesions is important, consensus guidelines regarding the evaluation and imaging of vascular anomalies does not exist to date. Here, the authors provide an overview of pediatric vascular lesions, current classification systems for characterizing these lesions, the various imaging modalities available, and recommendations for appropriate imaging evaluation. PMID:26705446

  14. Vascularity in thyroid neoplasms

    DEFF Research Database (Denmark)

    Larsen, Karen Kjaer; Andersen, Niels Frost; Melsen, Flemming;

    2006-01-01

    The aim of the present study was to evaluate the reliability of four different methods (vascular grading, Chalkley count, microvessel density (MVD) and stereological estimation) for quantifying intratumoral microvascularity in thyroid neoplasms, by comparing the variability within and between...... count should be the preferred method for assessing microvascularity in thyroid neoplasms. The diagnostic evaluation revealed a tendency towards higher degree of vascularity in FA compared to both FC and PC for all methods. No statistically significant association was seen between vascular density and...

  15. Evaluation of preconceptual plug designs using experts' judgement

    International Nuclear Information System (INIS)

    A number of preconceptual plug designs for an underground nuclear waste repository were to be evaluated based on the available information on plug materials and placement techniques. Because of complex environment and loading conditions, long time frame under consideration, rigid performance characteristics and considerable uncertainties present in preconceptual design and material properties, a qualitative and judgmental evaluation procedure was needed to supplement technical studies. A structured procedure was developed to qualitatively capture evaluator's views and reservations on the proposed preconceptual schemes. Since a thorough evaluation of each proposed plug scheme required in-depth experience and familiarity with many components of the plug, three knowledgeable experts with specialties in the most relevant aspects of the problem were independently interviewed. Each plug scheme was broken down into three subcomponents and each subcomponent was evaluated separately. The proposed schemes were then rated taking their subcomponents into consideration. Because the experts had different specialties, their subcomponent and overall ratings were not in full agreement. Each plug scheme's lowest overall rating was used as the most significant determinant of the judgmental preference categories reported in this study. The approach used discriminated between the proposed schemes for those with highest probability of being successful. The most preferred schemes were then reviewed with respect to the data produced in the technical analysis performed during the project. The results of the judgmental analysis were then synthesized and modified with results of the technical analysis to produce the preconceptual plug designs

  16. Borehole plugging by hydrothermal transport. A feasibility report

    International Nuclear Information System (INIS)

    The possibility of forming borehole plugs by hydrothermal transport was examined with respect to five systems, utilizing available literature data. In general, it would appear possible to create plugs with hydrothermal cements, with hydrothermally transported quartz, and with carbonates precipitated in-situ using carbon dioxide or carbon dioxide and water as reacting fluids. Hydrothermal cements appear to be most feasible from an engineering and economic point of view using a slurry with a lime-alumina-silica composition carried into the hole in a single pipe at temperatures in the range of 2000C and requiring only enough pressure to drive the mixture into the hole. Quartz or chalcedony plugs would be the most impervious, have the lowest chemical reactivity with groundwater, the lowest thermal expansion, and be most compatible with the wall rock. Deposition is likely to be slow, and there are severe engineering problems associated with a single pipe system carrying silica-rich solutions at temperatures in excess of 5000C at pressure of 2000 bars (30,000 psi). Calcite plugs could be formed as compatible plug materials in contact with a limestone or dolomite wall rock. It is not known whether non-porous plugs can be readily formed and there is also a problem of chemical reaction with percolating groundwater. The clay-water and sulfur-water systems do not appear to be viable plug systems. In-situ reconstitution of the wall rock does not appear to be an economically feasible possibility

  17. Dynamics of Surfactant Liquid Plugs at Bifurcating Lung Airway Models

    Science.gov (United States)

    Tavana, Hossein

    2013-11-01

    A surfactant liquid plug forms in the trachea during surfactant replacement therapy (SRT) of premature babies. Under air pressure, the plug propagates downstream and continuously divides into smaller daughter plugs at continuously branching lung airways. Propagating plugs deposit a thin film on airway walls to reduce surface tension and facilitate breathing. The effectiveness of SRT greatly depends on the final distribution of instilled surfactant within airways. To understand this process, we investigate dynamics of splitting of surfactant plugs in engineered bifurcating airway models. A liquid plug is instilled in the parent tube to propagate and split at the bifurcation. A split ratio, R, is defined as the ratio of daughter plug lengths in the top and bottom daughter airway tubes and studied as a function of the 3D orientation of airways and different flow conditions. For a given Capillary number (Ca), orienting airways farther away from a horizontal position reduced R due to the flow of a larger volume into the gravitationally favored daughter airway. At each orientation, R increased with 0.0005 surfactant distribution in airways and develop effective SRT strategies.

  18. Development of weld plugging for steam generator tubes of FBR

    International Nuclear Information System (INIS)

    This study was undertaken to develop a method of weld plugging of the heat-exchanger tubes of steam generator of Prototype FBR 'MONJU' in case these tubes are damaged for some reason. We studied mainly the shape of plug, welding procedure and effect of postweld heat treatment (PWHT). Evaporator tube sheet, tube and plug are made of 2-1/4Cr-1Mo steel and usually preheating and PWHT will be required for welding of this steel. The results of this study is as follows. 1) Plug was designed to make butt joint welding with grooved tube sheet around the tube hole to satisfy the requirements of plug designing, stress analysis, and good weldability. 2) TIG welding process was selected and certified its good weldability and good performance. 3) PWHT can be done by using high frequency induction heating method locally and also designing the plug to weld joint with tube sheet which was grooved around the tube hole. 4) Mock up test was done and it was certified that this plugging procedure has good weldability and good performance ability for Non Destructive Inspection. (author)

  19. Mechanical and thermo-mechanical analyses of the tapered plug for plugging of deposition tunnels. A feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Faelth, Billy (Clay Technology AB, Lund (Sweden)); Gatter, Patrik (Vattenfall Power Consultant AB, Stockholm (Sweden))

    2009-09-15

    This report presents results from a study that was carried out in order to examine the applicability of the tapered plug concept for plugging of deposition tunnels in the deep repository for spent nuclear fuel. The report presents results from mechanical and thermo-mechanical models of the tapered plug. The models were analyzed with 3DEC. The models included a portion of a deposition tunnel and its intersection with a main tunnel. In the deposition tunnel, a tapered concrete plug was installed. The plug was subjected to the combined load from the swelling backfill material and from pore pressure inside the deposition tunnel. The thermo-mechanical effects due to the heat generation in the spent fuel were also included in the analyses. Generic material parameter values for the concrete were used. The following items were studied: - Stresses and displacements in the plug. - Shear stresses and shear displacements in the rock-concrete interface. - Stress additions in the rock due to the loads. The sensitivity of the results to changes of constitutive models, to changes of the plug geometry and to pore water pressure in the rock-concrete interface was examined. The results indicate that the displacements in the plug will be within reasonable ranges but the stresses may locally be high enough that they exceed acceptable levels. However, they can be reduced by choice of advantageous plug geometry and by having a good rock-concrete bond. The results also show that the stress additions in the rock due to the thermal load may yield stresses that locally exceed the spalling strength of the rock. At most locations, however, the rock stresses will amount at lower levels. It was concluded that, with choice of an appropriate design, the tapered plug seems to be an applicable concept for plugging of deposition tunnels. It was also concluded that further studies of the tapered plug concept should use material properties parameter values for low-pH concrete. Further, they should also

  20. Mechanical and thermo-mechanical analyses of the tapered plug for plugging of deposition tunnels. A feasibility study

    International Nuclear Information System (INIS)

    This report presents results from a study that was carried out in order to examine the applicability of the tapered plug concept for plugging of deposition tunnels in the deep repository for spent nuclear fuel. The report presents results from mechanical and thermo-mechanical models of the tapered plug. The models were analyzed with 3DEC. The models included a portion of a deposition tunnel and its intersection with a main tunnel. In the deposition tunnel, a tapered concrete plug was installed. The plug was subjected to the combined load from the swelling backfill material and from pore pressure inside the deposition tunnel. The thermo-mechanical effects due to the heat generation in the spent fuel were also included in the analyses. Generic material parameter values for the concrete were used. The following items were studied: - Stresses and displacements in the plug. - Shear stresses and shear displacements in the rock-concrete interface. - Stress additions in the rock due to the loads. The sensitivity of the results to changes of constitutive models, to changes of the plug geometry and to pore water pressure in the rock-concrete interface was examined. The results indicate that the displacements in the plug will be within reasonable ranges but the stresses may locally be high enough that they exceed acceptable levels. However, they can be reduced by choice of advantageous plug geometry and by having a good rock-concrete bond. The results also show that the stress additions in the rock due to the thermal load may yield stresses that locally exceed the spalling strength of the rock. At most locations, however, the rock stresses will amount at lower levels. It was concluded that, with choice of an appropriate design, the tapered plug seems to be an applicable concept for plugging of deposition tunnels. It was also concluded that further studies of the tapered plug concept should use material properties parameter values for low-pH concrete. Further, they should also

  1. Plug and Play Process Control of a District Heating System

    DEFF Research Database (Denmark)

    Trangbaek, Klaus; Knudsen, Torben; Skovmose Kallesøe, Carsten

    2009-01-01

    The main idea of plug and play process control is to initialise and reconfigure control systems automatically. In this paper these ideas are applied to a scaled laboratory model of a district heating pressure control system.  First of all this serves as a concrete example of plug and play control......, secondly some of the first techniques developed for these problems are demonstrated by experiments. The main emphasis is on incremental modelling and control in order to make it possible to ``plug'' in a new sensor or actuator and make it ``play'' automatically....

  2. A Genre Classification Plug-in for Data Collection

    DEFF Research Database (Denmark)

    Lehn-Schiøler, Tue; Arenas-García, Jerónimo; Petersen, Kaare Brandt;

    2006-01-01

    This demonstration illustrates how the methods developed in the MIR community can be used to provide real-time feedback to music users. By creating a genre classifier plug-in for a popular media player we present users with relevant information as they play their songs. The plug-in can furthermor...... be used as a data collection platform. After informed consent from a selected set of users the plug-in will report on music consumption behavior back to a central server....

  3. A Genre Classification Plug-in for Data Collection

    OpenAIRE

    Lehn-Schiøler, Tue; Arenas-García, Jerónimo; Petersen, Kaare Brandt; Hansen, Lars Kai

    2006-01-01

    This demonstration illustrates how the methods developed in the MIR community can be used to provide real-time feedback to music users. By creating a genre classifier plug-in for a popular media player we present users with relevant information as they play their songs. The plug-in can furthermore be used as a data collection platform. After informed consent from a selected set of users the plug-in will report on music consumption behavior back to a central server.

  4. Poikiloderma vasculare atrophicans

    Directory of Open Access Journals (Sweden)

    Padmavathy L

    1994-01-01

    Full Text Available A 65 year old lady presented with generalised pruritus and discolouration of skin and mucous membranes of 5 years duration. The histopathology from the cutaneous lesions revealed features suggestive of poikiloderma vasculare atrophicans (PVA. Investigations did not reveal any underlying connective tissue disease,lymphoma or systemic disease. A diagnosis of idiopathic poikiloderma vasculare atrophicans was made.

  5. Poikiloderma vasculare atrophicans

    OpenAIRE

    Padmavathy L; Prasad PVS; Prasanna K; Rao L

    1994-01-01

    A 65 year old lady presented with generalised pruritus and discolouration of skin and mucous membranes of 5 years duration. The histopathology from the cutaneous lesions revealed features suggestive of poikiloderma vasculare atrophicans (PVA). Investigations did not reveal any underlying connective tissue disease,lymphoma or systemic disease. A diagnosis of idiopathic poikiloderma vasculare atrophicans was made.

  6. Evaluation of a concrete plug : From the Dome Plug Experiment DOMPLU at Äspö HRL

    OpenAIRE

    Kristiansson, Anders

    2014-01-01

    In SKB’s Äspö Hard Rock Laboratory (HRL) a full scale test of a concrete plug,part of a sealing structure for the depository of spent nuclear fuel, has been carriedout. The aim of this thesis is to evaluate the behavior of the concrete plug and howit corresponds to assumptions made during the design. The concrete plug is domeshaped, un-reinforced and casted in situ with low-pH concrete. It will be exposed tohigh water and swelling pressures and designed for a life span of 100 years. Duringthe...

  7. Vascular grading of angiogenesis

    DEFF Research Database (Denmark)

    Hansen, S; Grabau, D A; Sørensen, Flemming Brandt; Bak, M; Vach, W; Rose, C

    2000-01-01

    The study aimed to evaluate the prognostic value of angiogenesis by vascular grading of primary breast tumours, and to evaluate the prognostic impact of adding the vascular grade to the Nottingham Prognostic Index (NPI). The investigation included 836 patients. The median follow-up time was 11...... years and 4 months. The microvessels were immunohistochemically stained by antibodies against CD34. Angiogenesis was graded semiquantitatively by subjective scoring into three groups according to the expected number of microvessels in the most vascular tumour area. The vascular grading between observers...... had clinical impact for 24% of the patients, who had a shift in prognostic group, as compared to NPI, and implied a better prognostic dissemination. We concluded that the angiogenesis determined by vascular grading has independent prognostic value of clinical relevance for patients with breast cancer....

  8. [Vascular factors in glaucoma].

    Science.gov (United States)

    Mottet, B; Aptel, F; Geiser, M; Romanet, J P; Chiquet, C

    2015-12-01

    The exact pathophysiology of glaucoma is not fully understood. Understanding of the vascular pathophysiology of glaucoma requires: knowing the techniques for measuring ocular blood flow and characterizing the topography of vascular disease and the mechanisms involved in this neuropathy. A decreased mean ocular perfusion pressure and a loss of vascular autoregulation are implicated in glaucomatous disease. Early decrease in ocular blood flow has been identified in primary open-angle glaucoma and normal pressure glaucoma, contributing to the progression of optic neuropathy. The vascular damage associated with glaucoma is present in various vascular territories within the eye (from the ophthalmic artery to the retina) and is characterized by a decrease in basal blood flow associated with a dysfunction of vasoregulation. PMID:26597554

  9. Welding zircaloy thin tubes to end plugs

    International Nuclear Information System (INIS)

    This work aimed at optimizing parameters while welding zircaloy-2 tubes with end plugs, as a simulation of a part of the fabrication of the nuclear fuel pins. Samples were welded by tungsten-inert gas-arc welding (TIC) process under controlled atmosphere of pure argon. Some samples were welded using electron beam (EB) welding process. For samples welded using TIC process both the design of the welding chamber (size and tightness) , and the purity of the shielding atmosphere were found to have appreciable effect on the quality of the welded joint. Increasing the are length and/or the welding current increases grain growth and extends both fusion and heat-affected zones. However, heat input (are length and welding current) must be high enough to give complete penetration welds. Optimum are length of 1.2 mm was found to give good welds with the smallest possible heat affected and fusion zones. Optimum parameters of EB welding process (vacuum, welding current and EB amplitude) were determined. welds prepared by EB welding were found to have finer grain size and less extended fusion and heat-affected zones. Welds prepared by both TIC and EB processes were inspected visually, metallo graphically and by using X-ray radiography. Welds integrity were tested using helium leak and pressure tests. 7 figs

  10. Consequence assessment of hydrological communications through borehole plugs

    International Nuclear Information System (INIS)

    This report describes the effect of borehole plug integrity on consequence assessments performed for the Waste Isolation Pilot Plant. The study is based on scenarios described in the Final Environmental Impact Statement, Appendix K, for the WIPP, US Department of Energy, October 1980. The flow rates through a borehole, assumed to penetrate the waste storage location and to connect underlying and overlying aquifers, are determined as a function of the hydraulic conductance of the plugs. Similar calculations are performed for multiple boreholes communicating with the aquifers. It is concluded that low permeability plugs (less than 1 md) are not essential to satisfy public health and safety requirements at the WIPP, but rather that such plugs act as a redundant barrier in the multiple barrier isolation concept

  11. The Losing Battle Against Plug-and-Chug

    Science.gov (United States)

    Kortemeyer, Gerd

    2016-01-01

    I think most physics teachers would agree that two important components of a proper solution to a numerical physics problem are to first figure out a final symbolic solution and to only plug in numbers in the end. However, in spite of our best efforts, this is not what the majority of students is actually doing. Instead, they tend to plug numbers into formulas without considering the physical meaning of the equations, then frequently take the result and plug it into the next formula—a strategy known as "plug-and-chug." In this chain of calculations, frequently physical insights are lost. If teaching problem solving is proving ineffective, maybe it is possible to steer students onto the right path by posing the problems in different ways?

  12. Frictional Fluid Dynamics and Plug Formation in Multiphase Millifluidic Flow

    Science.gov (United States)

    Dumazer, Guillaume; Sandnes, Bjørnar; Ayaz, Monem; Mâløy, Knut Jørgen; Flekkøy, Eirik Grude

    2016-07-01

    We study experimentally the flow and patterning of a granular suspension displaced by air inside a narrow tube. The invading air-liquid interface accumulates a plug of granular material that clogs the tube due to friction with the confining walls. The gas percolates through the static plug once the gas pressure exceeds the pore capillary entry pressure of the packed grains, and a moving accumulation front is reestablished at the far side of the plug. The process repeats, such that the advancing interface leaves a trail of plugs in its wake. Further, we show that the system undergoes a fluidization transition—and complete evacuation of the granular suspension—when the liquid withdrawal rate increases beyond a critical value. An analytical model of the stability condition for the granular accumulation predicts the flow regime.

  13. Plug engine systems for future launch vehicle applications

    Science.gov (United States)

    Immich, H.; Parsley, R. C.

    1993-06-01

    Based on improved viability resulting from modern analysis techniques, plug nozzle rocket engines are once again being investigated with respect to advanced launch vehicle concepts. The advantage of these engines is the external expansion, which self-adapts to external pressure variation, as well as the short compact design for high expansion ratios. This paper describes feasible design options ranging from a plug nozzle engine with an annular combustion chamber to a segmented modular design, to the integration of a number of conventional engines around a common plug. The advantages and disadvantages of these options are discussed for a range of potential applications including single-stage-to-orbit (SSTO) vehicles, as well as upper stage vehicles such as the second stage of the SAeNGER HTOL launch vehicle concept. Also included is a discussion of how maturing computational fluid dynamic (CFD) modeling techniques could significantly reduce installed performance uncertainties, reducing plug engine development risk.

  14. Application of Inductive Monitoring System to Plug Load Anomaly Detection

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA Ames Research Center’s Sustainability Base is a new 50,000 sq. ft. LEED Platinum office building. Plug loads are expected to account for a significant portion...

  15. Waste isolation pilot plant (WIPP) borehole plugging program description

    International Nuclear Information System (INIS)

    The tests and experiments described attempt to provide a mix of borehole (with limited access) and in-mine (with relatively unlimited access) environments in which assessment of the various issues involved can be undertaken. The Bell Canyon Test provides the opportunity to instrument and analyze a plug in a high pressure region. The Shallow Hole Test permits application of best techniques for plugging and then access to both the top and bottom of the plug for further analysis. The Diagnostic Test Hole permits recovery of bench scale size samples for analysis and establishes an in-borehole laboratory in which to conduct testing and analysis in all strata from the surface into the salt horizon. The additional in mine experiments provide the opportunity to investigate in more detail specific effects on plugs in the salt region and allows evaluation of instrumentation systems

  16. Design and construction technology of the engineered scale plug in the TSX. Research document

    International Nuclear Information System (INIS)

    JNC has conducted the international joint project 'Tunnel Sealing Experiment (TSX)' with AECL at Underground Research Laboratory (URL) in Canada. Full-scale sealing technologies are applied to the underground tunnel in the TSX. Sealing technologies contain backfilling, plugging, grouting and so on. Since development of the plugging technology has impact to the whole sealing technology, understanding of the sealing performance of the plug is one of the most important problems. The TSX has full-scale concrete plug and clay plug. The sealing performance of the plugs has been monitored with the various sensors in and around the plugs, and assessed by the monitored data. This report summaries the design and construction technology of the plugs in the TSX. The design of the plugs focused on the impervious (seepage control). The concrete plug selected the shape and the size of the body and the size of the key considering the attachment between plug and rock mass. The clay plug selected the shape and the size of the key considering the volume of the EDZ. The material of the concrete plug was Low-Heat High-Performance Concrete. The material of the clay plug was pre-compacted bentonite blocks with sand. Feasibility of design and construction of both plugs were demonstrated with engineer scale and in-situ full-scale plugs. (author)

  17. EPIDEMIOLOCICAL INVESTIGATION ON THE SAFETY OF REVERSIBLE PLUGGING OF DUCTUS DEFERENS

    Institute of Scientific and Technical Information of China (English)

    ZHAOSheng-Cai; LIANYi-He; ZHANGShu-Ping

    1989-01-01

    The safety of rversible plugging was follow-up investigated in 21463 cases with ductus deferens plugged for 0.5-6 years, as compared with 2746 cases of non-plugging and with other contraceptive methods with plugging of ductus dcferens reported in the

  18. 30 CFR 250.1717 - After I permanently plug a well, what information must I submit?

    Science.gov (United States)

    2010-07-01

    ... Decommissioning Activities Permanently Plugging Wells § 250.1717 After I permanently plug a well, what information must I submit? Within 30 days after you permanently plug a well, you must submit form MMS-124... 30 Mineral Resources 2 2010-07-01 2010-07-01 false After I permanently plug a well,...

  19. Plug-in electric vehicles automated charging control

    OpenAIRE

    Dallinger, David; Kohrs, Robert; Mierau, Michael; Marwitz, Simon; Wesche, Julius

    2015-01-01

    This paper examines how plug-in electric vehicles can be managed to balance the fluctuation of renewable electricity sources. In this context, different control strategies are introduced. To investigate indirect control via electricity tariffs, an electricity market analysis is conducted of a system with a high share of generation from renewable electricity sources. The analysis uses driving data collected from battery electric and plug-in hybrid vehicles in a research project which means tha...

  20. Mesh Plug Repair of Inguinal Hernia; Single Surgeon Experience

    OpenAIRE

    Ahmet Serdar Karaca

    2013-01-01

    Aim: Mesh repair of inguinal hernia repairs are shown to be an effective and reliable method. In this study, a single surgeon%u2019s experience with plug-mesh method performs inguinal hernia repair have been reported. Material and Method: 587 patients with plug-mesh repair of inguinal hernia, preoperative age, body / mass index, comorbid disease were recorded in terms of form. All of the patients during the preoperative and postoperative hernia classification of information, duration of oper...

  1. Comparative end-plug study for tandem mirror reactors

    International Nuclear Information System (INIS)

    A comparative evaluation was made of several end plug configurations for tandem mirror fusion reactors with thermal barriers. The axicell configuration has been selected for further study and will be the basis for a detailed conceptual design study to be carried out over the next two years. The axicell end plug has a simple mirror cell produced by two circular coils followed by a transition coil and a yin-yang pair, which provides for MHD stability

  2. Plug flow formation and growth in da Vinci Fluids

    OpenAIRE

    Schwartz, Moshe; Blumenfeld, Raphael

    2009-01-01

    A new, da Vinci, fluid is described as a model for flow of dense granular matter. We postulate local properties of the fluid, which are generically different from ordinary fluids in that energy is dissipated by solid friction. We present the equation of flow of such a fluid and show that it gives rise to formation and growth of plug flow regions, which is characteristic of flow of granular matter. Simple explicit examples are presented to illustrate the evolution of plug flow regions.

  3. Engineering activities on the ITER representative diagnostic equatorial port plug

    International Nuclear Information System (INIS)

    Most of ITER diagnostic systems are integrated in port plugs, which are water cooled stainless steel structures inserted into the vacuum vessel ports. The port plug must provide basic functions such as neutron and gamma shielding, supporting the first wall armour (BSM), closing the vacuum vessel ports, while supporting the diagnostic equipments. ITER diagnostic port plug must resist a severe environment like high temperature due to neutron interaction with the structures and high electromechanical loading during disruptions events. CEA has contributed to the design and integration tasks in the frame of the representative equatorial port plug EQ no. 01, in particular on the engineering, structural and thermal finite element analysis. These detailed analyses have highlighted some design issues which were worked out through different solutions. This paper contains a description of the engineering activities performed such as: -The static mechanical calculations of the top plate closure system under disruption load. -The static mechanical calculations of the BSM attachment to the port plug. These two first studies led to design changes proposals which significantly improved the behaviour of the structures but also showed that the safety margin with respect to design limits is quite low. -The design of a Diagnostic Shield Module (DSM) integrated inside the port plug and a proposition of attachment scheme, with respect to disruption loads. The manufacturing of the DSM has been taken into account, as well as diagnostic integration inside the structure and maintenance aspects. -The thermal assessment of the port plug under neutronic load during normal operation, with the optimization of the cooling system. The maximum temperature calculated in normal operation has been reduced from 900 deg. C to less than 400 deg. C in the front plate; and the cooling arrangement at the back of the port plug has been simplified without important temperature increase.

  4. The welding of magnesium alloy plugs and canning (1960)

    International Nuclear Information System (INIS)

    The end or lateral welding of Mg-Zr plugs presents no special difficulties in the manufacture of fuel element slugs. The welding parameters were determined from penetrations and from the mechanical resistance. The unavoidable notching effect has received particular attention. It is possible to substitute a Mg-Zr plug without any modification of the optimum welding conditions and the various qualities of the weld. (author)

  5. Setting plug & abandonment barriers with minimum removal of tubulars

    OpenAIRE

    Nessa, Jon Olav

    2012-01-01

    The useful life of an offshore well is determined by the reserves which it contacts, the pressure support within the reservoir and the continued integrity of the wellbore. When a well has reached the end of its lifetime, plugging operations have to be conducted before permanent abandonment. Conventional Plug and Abandonment (P&A) operations will often require removing a section of the casing in order to create cross sectional barriers for well abandonment. Recently developed and field test...

  6. Hydrate plugging or slurry flow : effect of key variables

    Energy Technology Data Exchange (ETDEWEB)

    Dellecase, E.; Geraci, G.; Barrios, L.; Estanga, D.; Domingues, R.; Volk, M. [Tulsa Univ., Tulsa, OK (United States)

    2008-07-01

    Although oil and gas companies have proven design criteria and proper operating procedures to prevent hydrate plugs from forming, hydrates remain the primary issue in flow assurance. The costs associated with hydrate prevention affect project economics, particularly in deepwater pipelines. As such, there is an interest in developing a technology that allows hydrates to be transported as a slurry, while avoiding plugs. The feasibility of managing such hydrate flow was investigated. This study used a hydrate flow loop to investigate the effects of flow conditions on the transportability of a slurry in both steady-state and restart conditions. For most cases, uninhibited steady-state slurry flow conditions above 25 per cent water-cut were marginal, and most likely not feasible at 50 per cent water-cut or above. Liquid loading and velocity appeared to have a marginal effect on plugging tendency. However, minimum velocity may be needed to guarantee slurry transportation. Some of the important parameters and key variables that determine if a plug will form, particularly in restart conditions, include oil-water dispersion properties; oil-water phase segregation on the plugging tendency of model fluids; the location and state of the water; and the flow pattern. It was concluded that the plugging behaviour of oil systems changes with these variables, and with the oil-water chemistry. As such, specific strategies must be developed for each field. 4 refs., 1 tab., 14 figs.

  7. Size influence on the sealing performance of cementitious borehole plugs

    International Nuclear Information System (INIS)

    Flow tests have been conducted on cement plugs with diameters of 158.8 mm and 196.9 mm, and length to diameter ratios of one, in boreholes in basalt blocks and in steel pipes. Expansion strains and curing temperatures have been monitored on cement plugs in boreholes in basalt blocks, in PVC and in steel pipes with diameters from 25.4 mm to 196.9 mm and length to diameter ratios of one and two. During permeability tests, basalt blocks have fractured, presumably due to water injection pressure, cement expansion and packer pressure. Falling head tests have been performed on some block fractures to study the influence of the complicated interaction between a cement borehole plug (e.g. swelling and shrinkage alternations) and the rock, as well as of the normal stress across the fracture, on the hydraulic conductivity of a fracture intersecting a plugged borehole. The hydraulic conductivity of the cement plugs in the steel pipes varies between 3.57 x 10-11 cm/min and 3.65 x 10-9 cm/min. Cement swelling tests remain inconclusive about size effects, primarily because of instrumentation problems. Cement curing temperatures increase from small to large diameter cement plugs

  8. Pediatric vascular access

    International Nuclear Information System (INIS)

    Pediatric interventional radiologists are ideally suited to provide vascular access services to children because of inherent safety advantages and higher success from using image-guided techniques. The performance of vascular access procedures has become routine at many adult interventional radiology practices, but this service is not as widely developed at pediatric institutions. Although interventional radiologists at some children's hospitals offer full-service vascular access, there is little or none at others. Developing and maintaining a pediatric vascular access service is a challenge. Interventionalists skilled in performing such procedures are limited at pediatric institutions, and institutional support from clerical staff, nursing staff, and technologists might not be sufficiently available to fulfill the needs of such a service. There must also be a strong commitment by all members of the team to support such a demanding service. There is a slippery slope of expected services that becomes steeper and steeper as the vascular access service grows. This review is intended primarily as general education for pediatric radiologists learning vascular access techniques. Additionally, the pediatric or adult interventional radiologist seeking to expand services might find helpful tips. The article also provides education for the diagnostic radiologist who routinely interprets radiographs containing vascular access devices. (orig.)

  9. Pediatric vascular access

    Energy Technology Data Exchange (ETDEWEB)

    Donaldson, James S. [Northwestern University, Feinberg School of Medicine, Department of Medical Imaging, Children' s Memorial Hospital, Chicago, IL (United States)

    2006-05-15

    Pediatric interventional radiologists are ideally suited to provide vascular access services to children because of inherent safety advantages and higher success from using image-guided techniques. The performance of vascular access procedures has become routine at many adult interventional radiology practices, but this service is not as widely developed at pediatric institutions. Although interventional radiologists at some children's hospitals offer full-service vascular access, there is little or none at others. Developing and maintaining a pediatric vascular access service is a challenge. Interventionalists skilled in performing such procedures are limited at pediatric institutions, and institutional support from clerical staff, nursing staff, and technologists might not be sufficiently available to fulfill the needs of such a service. There must also be a strong commitment by all members of the team to support such a demanding service. There is a slippery slope of expected services that becomes steeper and steeper as the vascular access service grows. This review is intended primarily as general education for pediatric radiologists learning vascular access techniques. Additionally, the pediatric or adult interventional radiologist seeking to expand services might find helpful tips. The article also provides education for the diagnostic radiologist who routinely interprets radiographs containing vascular access devices. (orig.)

  10. High quality new type spark plug pressure sensor; Koseino plug gata shiatsu sensor ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Urakawa, H.; Yanagihara, S.; Kawa, T. [Tsukasa Sokken Co. Ltd., Tokyo (Japan); Enomoto, Y. [Musashi Institute of Technology, Tokyo (Japan); Sato, T. [Dai Ichi Institute of Technology, Kagoshima (Japan); Gotthard, E.

    1998-05-01

    Investigations were made on a spark plug type pressure sensor using GaPO4 piezoelectric material developed recently by AVL Corporation. This sensor has the ignition electrode installed decentered to assure the installing position for the pressure sensor, where the small pressure sensor with a diameter of 4.4 mm, model GU12P is installed on the side. Experiments were performed on this sensor, a water cooled sensor for comparison, and a cooling-free type sensor for reference. The engine was operated at an outlet cooling water temperature maintained constant at 80 degC, and experimented in a normal combustion condition with full load at 2000 rpm and 4000 rpm, in a knocking condition with full load at 2000 rpm, and in a transient condition from full load at 4000 rpm to no load at 1300 rpm. As a result, it was made clear that the spark plug type pressure sensor showed an output of the same level as that with the water cooled sensor in the normal combustion pressure. Load change drift under the transient condition was found as good as 2.5% FS at maximum. No effect of columnar vibration was discovered, and a knocking waveform of 14 kHz was observed. 6 refs., 12 figs., 1 tab.

  11. Congenital Vascular Malformation

    Science.gov (United States)

    ... clots, obstruction of major vessels, causing progressive limb asymmetry by overgrowth, and for cosmetic indications or because ... t he Vascular Disease Foundation (VDF) develops educational information and initiatives for patients, their families and friends, ...

  12. Vascular Access for Hemodialysis

    Science.gov (United States)

    ... for short-term use. [ Top ] What is an arteriovenous fistula? An AV fistula is a connection, made by ... to remove and return blood during hemodialysis. An arteriovenous (AV) fistula is a connection, made by a vascular surgeon, ...

  13. Heart and vascular services

    Science.gov (United States)

    ... Repair of aneurysms (dilated/enlarged portions) of the aorta and its branches Procedures may also be used ... Nutrition and lifestyle counseling, including smoking cessation and diabetes education Supervised exercise Alternative Names Circulatory system; Vascular ...

  14. Management of Vascular Malformations

    Directory of Open Access Journals (Sweden)

    Sadanori Akita, MD, PhD

    2014-03-01

    Conclusions: Treatment of vascular malformations is an integral part of multidisciplinary approaches. Venous malformations are more frequent in combination surgery, and if there are fewer complications, the patients’ satisfaction increases.

  15. Methodology for physical modeling of melter electrode power plug

    International Nuclear Information System (INIS)

    A method is presented for building and testing a one-third scale model of an electrode power plug used to supply up to 3000 amperes to a liquid fed ceramic melter. The method describes how a one-third scale model can be used to verify the ampacity of the power plug, the effectiveness of the power plug cooling system and the effect of the high amperage current on eddy current heating of rebar in the cell wall. Scale-up of the test data, including cooling air flow rate and pressure drop, temperature profiles, melter water jacket heat duty and electrical resistance is covered. The materials required to build the scale model are specified as well as scale surface finish and dimensions. The method for designing and testing a model power plug involves developing a way to recreate the thermal conditions including heat sources, sinks and boundary temperatures on a scale basis. The major heat sources are the molten glass in contact with the electrode, joule heat generation within the power plug, and eddy current heating of the wall rebar. The melting cavity heat source is modelled using a plate heater to provide radiant heat transfer to a geometrically similar, one-third scale electrode housed in a scale model of a melting cavity having a thermally and geometrically similar wall and floor. The joule heat generation within the power plug is simulated by passing electricity through the model power plug with geometrically similar rebar positioned to simulate the eddy heating phenomenon. The proposed model also features two forced air cooling circuits similar to those on the full design. The interaction of convective, natural and radiant heat transfer in the wall cooling circuit are considered. The cell environment and a melter water jacket, along with the air cooling circuits, constitute the heat sinks and are also simulated

  16. Vascular Effects of Histamine.

    Science.gov (United States)

    Ebeigbe, Anthony B; Talabi, Olufunke O

    2014-01-01

    Four subtypes of receptors (H1, H2, H3 and H4) mediate the actions of histamine. In the vascular wall, the effects of histamine are mediated via H1 and H2 receptors and the actions are modulated by H3 receptor subtype located on presynaptic neurones. Alterations in vascular responses to histamine are associated with experimental as well as a human form of hypertension, suggesting a role for histanine in cardiovascular regulation. PMID:26196559

  17. Digital vascular imaging (DVI)

    International Nuclear Information System (INIS)

    Digitization of the video signals from an image intensifier/TV chain, followed by subtraction, contrast enchancement and reconversion to analogue signals, enables high quality angiographic images to be obtained from an intravenous injection of contrast medium. As the examination is basically noninvasive it can be used in outpatients. The possibilities of Digital Vascular Imaging are demonstrated by images obtained from the various vascular regions using a triple-mode 14 in. image intensifier with a Plumbicon. TV tube. (Auth.)

  18. Thrombolysis in vascular surgery

    OpenAIRE

    Smith, Linn

    2015-01-01

    Background and aims: Thrombolysis is in common use in the treatment of acute forms of vascular disease. It may be used both systemically and locally, in the latter case through an endovascular approach, socalled catheter-directed thrombolysis. The aims of this thesis were to investigate how thrombolysis affects performance-related outcomes pertaining to vascular patency after thrombolysis, and how it affects patient safety and the development of complications. Metho...

  19. [Zaidemberg's vascularized radial graft].

    Science.gov (United States)

    Saint-Cast, Y

    2010-12-01

    In 1991, Carlos Zaidemberg described a new technique to repair scaphoid non-unions with a vascularized bone graft harvested from the radial styloid process. An anatomic study based on 30 dissections after colorized latex injection established the constancy of the radial styloid process's artery, while showing that its origin, course and length were subject to variations. In a retrospective series of 38 cases over a period of 10 years, the vascularized bone graft was indicated for: (1) scaphoid non-union with the presence of avascular changes of the proximal fragment (23 cases); (2) failed prior reconstruction with bone graft and internal fixation (nine cases); (3) degenerative styloid-scaphoid arthritis (three cases); (4) fracture on Preiser dystrophy (three cases). The five steps of the simplified operative technique without dissection of the vascular pedicle include: (1) longitudinal dorso-radial approach, identification of the periosteal portion of the radial styloid process artery; (2) incision of the first and second compartments, longitudinal arthrotomy under the second compartment; (3) styloidectomy and transversal resection of the scaphoid non-union and sclerotic bone; (4) elevation of the vascularized bone graft; (5) transversal and radial insertion of the vascularized bone graft, osteosynthesis by two or three K-wire touching the scaphoid's radial edge. Scaphoid union was obtained in 33 cases out of 38. The only postoperative complications were two transient radial paresthesia. The standardized surgical procedure using vascularized bone graft harvested from the radial styloid process provides an efficient scaphoid reconstruction. PMID:21087882

  20. Report on electric cars and plug-in hybrid cars; Redegoerelse - elbiler og plug-in hybridbiler

    Energy Technology Data Exchange (ETDEWEB)

    Elkjaer Toennesen, A.; Winther, K.; Noerregaard, K. (Teknologisk Institut, Taastrup (Denmark)); Larsen, Esben; Christensen, Linda; Kveiborg, O. (Danmarks Teknologiske Univ., Kgs. Lyngby (DTU) (Denmark))

    2010-04-15

    The Center for Green Transport at the Danish Transport Authority has prepared this statement in order to uncover driving technical aspects, user expectations and needs, and the environmental consequences of using electric and plug-in hybrid cars. An electric car is defined as a car driven by an electric motor that has a battery that can be charged with power from the grid. A plug-in hybrid car is defined as a car that combines gasoline or diesel engine with an electric motor with a battery which can be recharged with power from the grid. From an overall consideration related to the transport sector electric cars and plug-in hybrid cars have the major advantage that negative impacts on environment and climate from traffic can be reduced while the high mobility is maintained. Through an increased use of electric cars and plug-in hybrid cars, the many advantages attached to the car as an individual transportation form is maintained, while CO{sub 2} emissions etc. are reduced. Electric cars and plug-in hybrid cars is one of the technologies that are considered to have particularly great prospects in the medium term when it comes to promoting new technologies in transport. Another advantage of using electric vehicles is the power supply factor. An increased use of electricity in transport will reduce the need for and dependence on fossil fuels in the sector. Both electric cars and plug-in hybrid cars are expected to be used for storage of wind power, a possibility which is hardly available today. The plug-in hybrid car could meet some of the challenges facing the pure electric car, because it also can use conventional fuel. The report presents analyses based on three focus areas: a) Users' needs, expectations and economics in relation to vehicles; b) The technology - and hence the manufacturers' opportunities and challenges; c) Connection to the power grid. (ln)

  1. Plug-in electric vehicles integrating fluctuating renewable electricity

    Energy Technology Data Exchange (ETDEWEB)

    Dallinger, David

    2013-11-01

    This paper examines a method to model plug-in electric vehicles as part of the power system and presents results for the contribution of plug-in electric vehicles to balance the fluctuating electricity generation of renewable energy sources. The scientific contribution includes: - A novel approach to characterizing fluctuating generation. This allows the detailed comparison of results from energy analysis and is the basis to describe the effect of electricity from renewable energy sources and plug-in electric vehicles on the power system. - The characterization of mobile storage, which includes the description of mobility behavior using probabilities and battery discharging costs. - The introduction of an agent-based simulation approach, coupling energy markets and distributed grids using a price-based mechanism design. - The description of an agent with specific driving behavior, battery discharging costs and optimization algorithm suitable for real plug-in vehicles and simulation models. - A case study for a 2030 scenario describing the contribution of plug-in electric vehicles to balance generation from renewable energy sources in California and Germany.

  2. The Plug-in Concept: Technology and Aesthetics of Change

    Directory of Open Access Journals (Sweden)

    Peter Šenk

    2013-01-01

    Full Text Available The architecture concept of plug-in is based on the duality of the infrastructure system and units or elements connected to it. In the context of megastructures, the concept was most vividly characterised by works of Archigram and Japanese Metabolists in the 1960s and early 1970s. Blurring the boundary between the building and the city, the plug-in concept outgrew architectural boundaries and was slowly transformed into an urbanistic concept.The paper presents the cultural context relevant to contemporaneity, which influenced specific development of the technology-driven concept of plug-in in the British Archigram Group and Japanese Metabolists. Based on the aesthetics of change and incompleteness, which was characterised by similar architectural manifestations despite entirely different cultural backgrounds, the plug-in concept foreshadowed social transformation based on freedom, individualisation and mobility in an utopian manner and held a promise of urban development with adaptability to unpredictable needs and desires of residents, who would become its co-creators with an active approach.Although the revolutionary sixties are quite some time behind, the plug-in concept in its commodified form has become and remained operational and relevant at least on the metaphorical level; in the contemporary space it is evident primarily in urbanism and not as much in its original architectural form.

  3. Antioxidants and vascular health.

    Science.gov (United States)

    Bielli, Alessandra; Scioli, Maria Giovanna; Mazzaglia, Donatella; Doldo, Elena; Orlandi, Augusto

    2015-12-15

    Oxygen free radicals and other reactive oxygen species (ROS) are common products of normal aerobic cellular metabolism, but high levels of ROS lead to oxidative stress and cellular damage. Increased production of ROS favors vascular dysfunction, inducing altered vascular permeability and inflammation, accompanied by the loss of vascular modulatory function, the imbalance between vasorelaxation and vasoconstriction, and the aberrant expression of inflammatory adhesion molecules. Inflammatory stimuli promote oxidative stress generated from the increased activity of mitochondrial nicotinamide adenine dinucleotide phosphate oxidase, particularly of the Nox4 isoform, with the consequent impairment of mitochondrial β-oxidation. Vascular dysfunction due to the increase in Nox4 activity and ROS overproduction leads to the progression of cardiovascular diseases, diabetes, inflammatory bowel disease, and neurological disorders. Considerable research into the development of effective antioxidant therapies using natural derivatives or new synthetic molecules has been conducted. Antioxidants may prevent cellular damage by reducing ROS overproduction or interfering in reactions that involve ROS. Vitamin E and ascorbic acid are well known as natural antioxidants that counteract lipid peroxidative damage by scavenging oxygen-derived free radicals, thus restoring vascular function. Recently, preliminary studies on natural antioxidants such as goji berries, thymus, rosemary, green tea ginseng, and garlic have been conducted for their efficacy in preventing vascular damage. N-acetyl-cysteine and propionyl-L-carnitine are synthetic compounds that regulate ROS production by replacing endogenous antioxidants in both endothelial and smooth muscle cells. In this review, we consider the molecular mechanisms underlying the generation of oxidative stress-induced vascular dysfunction as well as the beneficial effects of antioxidant therapies. PMID:26585821

  4. The role of MRI for the evaluation of atrial septal defects before and after percutaneous occlusion with the Amplatzer Septal Occluder trademark

    International Nuclear Information System (INIS)

    Purpose: Evaluation of morphologic and functional MRI of atrial septal defects (ASD) before and after percutaneous occlusion with the Amplatzer Septal Occluder (AOC). Comparison of MRI with transesophageal echocardiography (TEE), balloon measurement (IVBM) and cardiac catheterization with shunt quantification (CCSQ). Materials and Methods: Twenty patients with ASD were examined before and three months after AOC implantation. ECG-triggered, breath-hold T1-weighted Turbo Spin Echo Segmented FLASH 2D and dynamic turbo-FLASH-GRE sequences after application of 0,2 mmol gadolinium DTPA per kg body weight were obtained in a 1.5 T MRI system. Defect size, and distance to coronal sinus (CS) and right upper pulmonary vein (RUPV) were determined for pre-interventional planning, and the AOC size was measured quantitatively for post-interventional follow-up. The shunts were evaluated qualitatively (occurrence of jets), semiquantitatively (jet length, turbulence square product) and quantitatively (flow measurement in the thoracic aorta and in the left and right pulmonary arteries). Results: The average size of the ASD measured by MRI was 17.6 mm (11-24.8 mm) in the axial view, 15.9 mm (10.8-28.9 mm) in the sagittal view and 16.4 mm (12.1-24.8 mm) in the short axis view. In comparison, the average defect size was 15 mm (8-24 mm) by TEE and 20 mm (13-27 mm) by IVBM. The average distance to the RUPV was 17 mm (9.6-21.9 mm) and to the CS 11.2 mm (5-17 mm). The AOC was visualized with only minimal artifacts. Qualitative analysis of the MRI findings revealed an occurence of jets in 17/20 patients. Semiquantitative analysis documented a high correlation for jet length and square product of the turbulence to defect size r=0.81 resp. r=0.82. Mean QP/QS-ratio measured by MR-volumetry was 1.6±0.29 and by MR-flow 1.6±0.26. The corresponding measurements were 1.7±0.3 for TEE and 1.5±0.5 for CCSQ. In comparison to TEE, the correlation coefficient was r=0.96 for MR-volumetry and r=0.85 for

  5. Interaction of clay and concrete plugs - Plugging of 5 m deep hole KA1621G01 at Aespoe

    Energy Technology Data Exchange (ETDEWEB)

    Pusch, Roland [Drawrite AB, Lund (Sweden); Luleaa Technical Univ., Luleaa (Sweden); Ramqvist, Gunnar [Eltekno AB, Figeholm (Sweden)

    2011-11-15

    Sealing of deep boreholes in repository rock is planned to be made by installing dense smectite clay plugs where the rock is low-permeable and casting concrete where the holes intersect water-bearing fracture zones. Such zones have to be stabilized before sealing starts because fragments of rock can otherwise fall off and make it difficult to bring equipment for concrete casting and clay plug units down. These parts of the holes are filled with concrete and clay plugs are then inserted up to the nearest fracture zone where concrete is filled to the required level etc. The role of the concrete in the hole and in the closest part of the surrounding fracture zone is to provide stable parts that are sufficiently fine-porous to prevent clay particles from contacting clay plugs to migrate into the fractures and be lost by erosion. While the larger parts of long clay plugs are believed to stay largely intact chemically for hundreds of thousands of years, the parts adjacent to concrete plugs may undergo changes and so can the concrete plugs themselves. The objective of the presently reported project was to identify the detailed processes and quantify associated changes in physical properties by investigating samples of clay and concrete from a 2.5 m long plug of clay over which an equally long concrete plug had been cast and left to rest for 3 years. The outcome of the investigations was that significant chemically induced changes in mineralogy and physical performance had occurred within a few centimetres distance from the clay/concrete contact but that virtually no changes had taken place at larger distance. A comprehensive laboratory study including X-ray diffraction (XRD), X-ray fluorescence (XRF) and electron microscopy study (SEM and TEM) on the sample material was performed including also dual beam (combined ion and electron) microscopy. It was found that the clay had infiltrated the contacting concrete plug after filling of the borehole since clay was detected both

  6. Eddy Current Minimizing Flow Plug for Use in Flow Conditioning and Flow Metering

    Science.gov (United States)

    England, John Dwight (Inventor); Kelley, Anthony R. (Inventor)

    2015-01-01

    An eddy-current-minimizing flow plug has open flow channels formed between the plug's inlet and outlet. Each open flow channel includes (i) a first portion that originates at the inlet face and converges to a location within the plug that is downstream of the inlet, and (ii) a second portion that originates within the plug and diverges to the outlet. The diverging second portion is approximately twice the length of the converging first portion. The plug is devoid of planar surface regions at its inlet and outlet, and in fluid flow planes of the plug that are perpendicular to the given direction of a fluid flowing therethrough.

  7. Integrity evaluation of ice plugged pipes applied on short jacket

    Energy Technology Data Exchange (ETDEWEB)

    Park, Yeong Don; Son, Geum Su [Korea Hydro and Nuclear Power Co., Ltd, Ulsan (Korea, Republic of); Yun, Doo Ri; Ha, Byeong Guk; Hwang, Sang Moon; Kang, Beom Soo [Busan National University, Busan (Korea, Republic of)

    2002-04-01

    In special industrial fields such as nuclear power plants and chemical plants, it is often necessary to repair system components without plant shutdown or drainage of system having many piping structures which may have hazardous or expensive fluid. A temporary ice plugging method for blocking internal flow is considered as a useful method in that case. According to the pipe freezing guideline of the nuclear power plant, the length of a freezing jacket must be longer than twice of the pipe diameter. However, for applying the ice plugging to short pipes which do not have enough freezing length because of geometrical configuration, it is inevitable to use shorter jacket less than twice of the pipe diameter. In this study, the integrity evaluation for short pipes in the nuclear power plant is conducted by an experiment and the finite element analysis. From the results, the ice plugging process in short pipes can be safely carried out without any plastic deformation and fracture.

  8. Outlet plug for recirculation loop of nuclear reactor

    International Nuclear Information System (INIS)

    A stopper apparatus for use in blocking the unvalved nozzle of a cooling fluid filled nuclear reactor pressure vessel includes a plug, typically in the shape of a frustoconical member having inflatable gaskets for sealing against a seat of generally unknown surface characteristics and means for positioning and urging the plug into position to seal the nozzle. The plug is typically positioned by suspension cables whereby the apparatus can be temporarily inserted and removed from the pressure vessel. The urging means is generally a two-way hydraulically driven jack controlled by remotely-actuated hydraulic lines. The apparatus is a tool which permits temporary sealing of a submerged outlet in a reactor vessel to permit maintenance on a fluid recirculation loop

  9. Charge It: The Promise of Plug-in Electric Hybrids

    OpenAIRE

    Recker, W. W.; Kang, J.E.

    2011-01-01

    With rising energy prices and battery improvements, the plug-in hybrid electric vehicle, a variant of the betterknown self-charging hybrid electric vehicle, is fast gaining popularity. Because plug-in hybrids can recharge via a wall socket while resting, they can run purely on electric power for many trips without having to revert to gasoline. This significantly reduces emissions over conventional hybrids, which can only recharge while they’re operating and are thus more likely to rely on t...

  10. Warning: safety risk with some Apple AC Wall Plug Adapters

    CERN Multimedia

    CERN IT department

    2016-01-01

    Dear Mac and iOS Users, Apple has determined that some of its two prong Apple AC wall plug adapters may break and create a risk of electrical shock.   CERN users can now exchange their affected Apple wall plug adapters at the Service Desk. To find out if your adapter is affected and for any further information concerning the procedure to follow to exchange it, please check the following URL: https://cern.service-now.com/service-portal/view-outage.do?n=OTG0028639.

  11. Nuclear determination of saturation profiles in core plugs

    International Nuclear Information System (INIS)

    A method to determine liquid saturations in core plugs during flooding is of importance when the relative permeability and capillary pressure function are to be determined. This part of the EFP-95 project uses transmission of γ-radiation to determine these saturations. In γ-transmission measurements, the electron density of the given substance is measured. This is an advantage as compared to methods that use electric conductivity, since neither oil nor gas conducts electricity. At the moment a single 137Cs-source is used, but a theoretical investigation of whether it is possible to determine three saturations, using two radioactive sources with different γ-energies, has been performed. Measurements were made on three core plugs. To make sure that the measurements could be reproduced, all the plugs had a point of reference, i.e. a mark so that it was possible to place the plug same way every time. Two computer programs for calculation of saturation and porosity and the experimental setup are listed. (EG)

  12. Seating tool for preparing molded-plug terminations on FCC

    Science.gov (United States)

    Chambers, C. M.; Corum, C. C.

    1971-01-01

    Hand-operated tool positions and seats window piece and conductor spacer onto conductors of two stripped cables during process of terminating cables with molded plug. Tool accommodates cables up to 3 in. wide and is used in conjunction with folding tools.

  13. Plug-In Electric Vehicle Handbook for Consumers (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2011-09-01

    Plug-in electric vehicles (PEVs) are entering the automobile market and are viable alternatives to conventional vehicles. This guide for consumers describes the basics of PEV technology, PEV benefits, how to select the right PEV, charging a PEV, and PEV maintenance.

  14. Plug-In Electric Vehicle Handbook for Fleet Managers (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2012-04-01

    Plug-in electric vehicles (PEVs) are entering the automobile market and are viable alternatives to conventional vehicles. This guide for fleet managers describes the basics of PEV technology, PEV benefits for fleets, how to select the right PEV, charging a PEV, and PEV maintenance.

  15. Project Gasbuggy well plugging and site restoration plan

    Energy Technology Data Exchange (ETDEWEB)

    1978-07-01

    The operational plan for conducting the final restoration work at the site of the first U.S. underground nuclear experiment for the stimulation of low-productivity natural gas reservoirs is given. The plan includes well plugging procedures, surface facilities decontamination and removal procedures, radiological guidelines, and environmental considerations.

  16. PIXASTIC: STEGANOGRAPHY BASED ANTI-PHISHING BROWSER PLUG-IN

    Directory of Open Access Journals (Sweden)

    P.Thiyagarajan

    2012-04-01

    Full Text Available In spite of existence of many standard security mechanisms for ensuring secure e- Commerce business, users still fall prey for onlin e attacks. One such simple but powerful attack is ‘Phishing’. Phishing is the most alarming threat in the e-Commerce world and effective anti-phishing technique is the need of the hour. This paper focuses on a novel anti-phishing browser plug-in which uses information hiding technique - Steganography. A Robust Message based Image Steganography (RMIS algorithm has been proposed. The same has been incorporated in the form of a browser plug-in (safari called Pixastic. Pixastic is tested in an online banking scenario and it is compared with other well-known anti-phishing plug-in methods in practice. Various parameters such as robustness, usability and its behavior on various attacks have been analysed. From experimental results, it is ev ident that our method Pixastic performs well compared to other anti-phishing plug-ins.

  17. Axicell design for the end plugs of MFTF-B

    International Nuclear Information System (INIS)

    Certain changes in the end-plug design in the Mirror Fusion Test Facility (MFTF-B) are described. The Laboratory (LLNL) proposes to implement these changes as soon as possible in order to construct the machine in an axicell configuration. The present physics and technology goals as well as the project cost and schedule will not be affected by these changes

  18. Analysis of supersonic plug nozzle flowfield and heat transfer

    Science.gov (United States)

    Murthy, S. N. B.; Sheu, W. H.

    1988-01-01

    A number of problems pertaining to the flowfield in a plug nozzle, designed as a supersonic thruster nozzle, with provision for cooling the plug with a coolant stream admitted parallel to the plug wall surface, were studied. First, an analysis was performed of the inviscid, nonturbulent, gas dynamic interaction between the primary hot stream and the secondary coolant stream. A numerical prediction code for establishing the resulting flowfield with a dividing surface between the two streams, for various combinations of stagnation and static properties of the two streams, was utilized for illustrating the nature of interactions. Secondly, skin friction coefficient, heat transfer coefficient and heat flux to the plug wall were analyzed under smooth flow conditions (without shocks or separation) for various coolant flow conditions. A numerical code was suitably modified and utilized for the determination of heat transfer parameters in a number of cases for which data are available. Thirdly, an analysis was initiated for modeling turbulence processes in transonic shock-boundary layer interaction without the appearance of flow separation.

  19. Microscopic weld evaluation of FBTR end plug welds

    International Nuclear Information System (INIS)

    SS316 Stainless steel has been chosen as a reference cladding material for Fast Breeder Test Reactor. Both the ends of the clad tubes are encapped with a solid stainless steel plug by Tungsten Inert Gas welding processes. Due to the thick-thin geometry of the end plug and the fuel clad tube, getting defect free weld joint is a challenging task. Microscopic weld evaluation of the weld defects of these end plug welds have been carried out as per standard ASTM metallography practice. Requirement of the good quality weld joint is very essential to contain the fission gas release and to enable it to sustain the high burn up of the fuel in the nuclear reactor. This paper presents the typical weld defects encountered during the development and fabrication of the actual fuel pin and it also shows some of the weld characteristics like multiple weld pool, spherical weld pool, through and through weld penetration, outer edge depression at the tube side and the plug side of the weld pool observed during the pin fabrication campaign. (author)

  20. jMRUI Version 4: A Plug-in Platform

    Czech Academy of Sciences Publication Activity Database

    Stefan, D.; Andrasecu, A.; Popa, E.; Rabeson, H.; Štrbák, Oliver; Starčuk jr., Zenon; Cabanas, M.; van Ormondt, D.; Graveron-Demilly, D.

    Chania: IEEE, 2008, s. 344-346. ISBN 978-1-4244-2496-2. [IEEE Workshop on Imaging Systems and Techniques Proceedings - IST 2008. Chania (GR), 10.09.2008-12.09.2008] Institutional research plan: CEZ:AV0Z20650511 Keywords : MR Spectroscopy * MRS * MRSI * jMRUI Software Package * Java * Plug-ins * Quantitation Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  1. End plug welding of nuclear fuel elements-AFFF experience

    International Nuclear Information System (INIS)

    Advanced Fuel Fabrication Facility is engaged in the fabrication of mixed oxide (U,Pu)O2 fuel elements of various types of nuclear reactors. Fabrication of fuel elements involves pellet fabrication, stack making, stack loading and end plug welding. The requirement of helium bonding gas inside the fuel elements necessitates the top end plug welding to be carried out with helium as the shielding gas. The severity of the service conditions inside a nuclear reactor imposes strict quality control criteria, which demands for almost defect free welds. The top end plug welding being the last process step in fuel element fabrication, any rejection at this stage would lead to loss of effort prior to this step. Moreover, the job becomes all the more difficult with mixed oxide (MOX) as the entire fabrication work has to be carried out in glove box trains. In the case of weld rejection, accepted pellets are salvaged by cutting the clad tube. This is a difficult task and recovery of pellets is low (requiring scrap recovery operation) and also leads to active metallic waste generation. This paper discusses the experience gained at AFFF, in the past 12 years in the area of end plug welding for different types of MOX fuel elements

  2. Plant vascular development

    NARCIS (Netherlands)

    Rybel, De Bert; Mähönen, Ari Pekka; Helariutta, Yrjö; Weijers, Dolf

    2016-01-01

    Vascular tissues in plants are crucial to provide physical support and to transport water, sugars and hormones and other small signalling molecules throughout the plant. Recent genetic and molecular studies have identified interconnections among some of the major signalling networks that regulate

  3. Renal posttransplant's vascular complications

    Directory of Open Access Journals (Sweden)

    Bašić Dragoslav

    2003-01-01

    Full Text Available INTRODUCTION Despite high graft and recipient survival figures worldwide today, a variety of technical complications can threaten the transplant in the postoperative period. Vascular complications are commonly related to technical problems in establishing vascular continuity or to damage that occurs during donor nephrectomy or preservation [13]. AIM The aim of the presenting study is to evaluate counts and rates of vascular complications after renal transplantation and to compare the outcome by donor type. MATERIAL AND METHODS A total of 463 kidneys (319 from living related donor LD and 144 from cadaveric donor - CD were transplanted during the period between June 1975 and December 1998 at the Urology & Nephrology Institute of Clinical Centre of Serbia in Belgrade. Average recipients' age was 33.7 years (15-54 in LD group and 39.8 (19-62 in CD group. Retrospectively, we analyzed medical records of all recipients. Statistical analysis is estimated using Hi-squared test and Fischer's test of exact probability. RESULTS Major vascular complications including vascular anastomosis thrombosis, internal iliac artery stenosis, internal iliac artery rupture obliterant vasculitis and external iliac vein rupture were analyzed. In 25 recipients (5.4% some of major vascular complications were detected. Among these cases, 22 of them were from CD group vs. three from LD group. Relative rate of these complications was higher in CD group vs. LD group (p<0.0001. Among these complications dominant one was vascular anastomosis thrombosis which occurred in 18 recipients (17 from CD vs. one from LD. Of these recipients 16 from CD lost the graft, while the rest of two (one from each group had lethal outcome. DISCUSSION Thrombosis of renal allograft vascular anastomosis site is the most severe complication following renal transplantation. In the literature, renal allograft thrombosis is reported with different incidence rates, from 0.5-4% [14, 15, 16]. Data from the

  4. Strangulated bowel obstruction resulting from mesh plug migration after open inguinal hernioplasty:case report

    Institute of Scientific and Technical Information of China (English)

    LIANG Xiao; CAI Xiu-jun; YU Hong; WANG Yi-fan

    2008-01-01

    @@ The use of mesh plug in hernioplasty was introduced by Shulman et al 1 in 1990 as a"rolled plug"fixed with two stitches to close the internal inguinal ring.Robbins and Rutkow 2 described their mesh plug technique in 1993.

  5. Neutronics analysis of the IVVS/GDC plug in ITER

    International Nuclear Information System (INIS)

    Highlights: ► 3D neutronics analysis of the In-Vessel Viewing System (IVVS) and the Glow Discharge Cleaning (GDC) plug unit. ► Occupational dose rates around the isolated IVVS/GDC head are calculated on the basis of the rigorous 2-step (R2S) approach. ► The GDC head is shown to dominate the decay gamma activity and the shutdown dose rate around the isolated IVVS/GDC plug. ► All components, except the Be protective layer of the GDC probe, are shown to be classifiable as low level radwaste. - Abstract: A neutronics analysis has been performed to provide the input required for the design strategy for the In-Vessel Viewing System (IVVS) and the Glow Discharge Cleaning (GDC) plug units in the ITER tokamak. The focus of the analysis has been on operational loads to the GDC electrode head in the shielding position and on the activation and the decay photon radiation absorbed in the structural components of the entire system. To estimate the conditions for maintenance scenarios, the occupational dose rate around the isolated IVVS/GDC head has been calculated assuming the ITER SA2 irradiation scenario. The Rigorous 2 Step (R2S) method, developed previously at KIT, has been employed for the calculation of the shutdown dose rates. The GDC head, which is subjected to the highest neutron loads, gets heavily activated and dominates the decay gamma activity of the entire plug. Accordingly, the shutdown dose rate around the IVVS/GDC plug is dominated by the GDC electrode head. It is therefore recommended to separate the GDC head from the system prior to further operations inside the Hot Cell. All components, except the Be protective layer of the GDC probe, were shown to be classifiable as low level radwaste according to the French regulations.

  6. Alternate tube plugging criteria for steam generator tubes

    Energy Technology Data Exchange (ETDEWEB)

    Cueto-Felgueroso, C.; Aparicio, C.B. [Tecnatom, S.A., Madrid (Spain)

    1997-02-01

    The tubing of the Steam Generators constitutes more than half of the reactor coolant pressure boundary. Specific requirements governing the maintenance of steam generator tubes integrity are set in Plant Technical Specifications and in Section XI of the ASME Boiler and Pressure Vessel Code. The operating experience of Steam Generator tubes of PWR plants has shown the existence of some types of degradatory processes. Every one of these has an specific cause and affects one or more zones of the tubes. In the case of Spanish Power Plants, and depending on the particular Plant considered, they should be mentioned the Primary Water Stress Corrosion Cracking (PWSCC) at the roll transition zone (RTZ), the Outside Diameter Stress Corrosion Cracking (ODSCC) at the Tube Support Plate (TSP) intersections and the fretting with the Anti-Vibration Bars (AVBs) or with the Support Plates in the preheater zone. The In-Service Inspections by Eddy Currents constitutes the standard method for assuring the SG tubes integrity and they permit the monitoring of the defects during the service life of the plant. When the degradation reaches a determined limit, called the plugging limit, the SG tube must be either repaired or retired from service by plugging. Customarily, the plugging limit is related to the depth of the defect. Such depth is typically 40% of the wall thickness of the tube and is applicable to any type of defect in the tube. In its origin, that limit was established for tubes thinned by wastage, which was the predominant degradation in the seventies. The application of this criterion for axial crack-like defects, as, for instance, those due to PWSCC in the roll transition zone, has lead to an excessive and unnecessary number of tubes being plugged. This has lead to the development of defect specific plugging criteria. Examples of the application of such criteria are discussed in the article.

  7. Vascular manifestations of Behcet's disease

    Directory of Open Access Journals (Sweden)

    Regina Georgiyeva Goloeva

    2010-04-01

    Conclusion. Vascular disorders in BD were diagnosed in one fourth of the patients, mainly in young male patients. Severe thromboses with the development of chronic venous insignificance, Budd-Chiari syndrome, pulmonary and iliac artery aneurysms, and arterial thromboses were observed in male patients only. Vascular events were associated with erythema nodosum and epididymitis; in these concomitances, the vascular risk was substantially increased. Vascular death rates were 2,2%.

  8. Field-test programs of borehole plugs in southeastern New Mexico

    International Nuclear Information System (INIS)

    This paper gives a general overview of the repository-sealing field test effort being conducted by Sandia National Laboratories in support of the Waste Isolation Pilot Plant in southeast New Mexico. Summary descriptions of supporting activities, such as performance assessment and plugging materials development, are included to create the connection between modeling and laboratory activities as they relate to field results. Results of tests on a portion of a 17-year-old plug (Plug 217) recovered from a mine horizon and the Bell Canyon Test, in which a cement plug was emplaced to isolate a naturally pressurized aquifer, are given. Conclusions from these field plugging tests are included

  9. Plant Vascular Biology 2010

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Biao

    2014-11-17

    This grant supported the Second International Conference on Plant Vascular Biology (PVB 2010) held July 24-28, 2010 on the campus of Ohio State University, Columbus, Ohio. Biao Ding (Ohio State University; OSU) and David Hannapel (Iowa State University; ISU) served as co-chairs of this conference. Biao Ding served as the local organizer. PVB is defined broadly here to include studies on the biogenesis, structure and function of transport systems in plants, under conditions of normal plant growth and development as well as of plant interactions with pathogens. The transport systems cover broadly the xylem, phloem, plasmodesmata and vascular cell membranes. The PVB concept has emerged in recent years to emphasize the integrative nature of the transport systems and approaches to investigate them.

  10. Vascular cognitive impairment

    Directory of Open Access Journals (Sweden)

    N.V. Vakhnina

    2014-05-01

    Full Text Available Vascular pathology of the brain is the second most common cause of cognitive impairment after Alzheimer's disease. The article describes the modern concepts of etiology, pathogenetic mechanisms, clinical features and approaches to diagnosis and therapy of vascular cognitive impairment (VCI. Cerebrovascular accident, chronic cerebral circulatory insufficiency and their combination, sometimes in combination with a concomitant neurodegenerative process, are shown to be the major types of brain lesions leading to VCI. The clinical presentation of VCI is characterized by the neuropsychological status dominated by impairment of the executive frontal functions (planning, control, attention in combination with focal neurological symptoms. The diagnosis is based on comparing of the revealed neuropsychological and neurological features with neuroimaging data. Neurometabolic, acetylcholinergic, glutamatergic, and other vasoactive drugs and non-pharmacological methods are widely used to treat VCI. 

  11. Pathophysiology of vascular dementia

    Directory of Open Access Journals (Sweden)

    Rizzo Claudia

    2009-11-01

    Full Text Available Abstract The concept of Vascular Dementia (VaD has been recognized for over a century, but its definition and diagnostic criteria remain unclear. Conventional definitions identify the patients too late, miss subjects with cognitive impairment short of dementia, and emphasize consequences rather than causes, the true bases for treatment and prevention. We should throw out current diagnostic categories and describe cognitive impairment clinically and according to commonly agreed instruments that document the demographic data in a standardized manner and undertake a systematic effort to identify the underlying aetiology in each case. Increased effort should be targeted towards the concept of and criteria for Vascular Cognitive Impairment and Post-Stroke Dementia as well as for genetic factors involved, especially as these categories hold promise for early prevention and treatment.

  12. Earth dam plug for sealing of underground repositories

    International Nuclear Information System (INIS)

    Document available in extended abstract form only. As a part of the stepwise more detailed design of the sealing and closure of the Swedish final repository for short lived radioactive waste, a concept for an 'earth dam plug' has been developed by SKB. The function of the plug is to decrease the ground water flow through the rock vaults and silo. The plug consists of the following principal parts: 1. Tunnel sections filled with bentonite which acts as a hydraulic seal 2. Tunnel sections filled with a mixture of 30% bentonite and 70% crushed rock that act as a transition material and transfers the load from the swelling bentonite to the adjacent backfill material and the rock. 3. Temporary concrete walls that are needed for the installation 4. Backfill material consisting of crushed rock that confines the transition material and transfers the load to the rock walls, roof and floor. The transition material is compacted in place in inclined layers, a method originally developed by SKB for backfilling of deposition tunnels in the KBS-3 repository. The tunnel contour is adjusted so that the transition material is confined by the crushed rock backfill. As the bentonite is saturated it will expand and build up a swelling pressure against the transition material. This will be compressed. The major part of the load will be transferred to the crushed rock as a smaller part of the load will be transferred to the rock contact. Analytic calculations show that for the geometry illustrated to the left in Figure 1 the combined compression of the transition material and the deformation of the crushed rock will result in a displacement of the transition material in-between 0,15 and 0,55 m for a swelling pressure of 2 Mpa. This is based on relatively conservative assumptions for the deformation properties of the crushed rock. If the displacement of the transition material leads to zones with higher hydraulic conductivity or other damages the bentonite is assumed to move into the zone

  13. Pathophysiology of vascular dementia

    OpenAIRE

    Rizzo Claudia; Duro Giovanni; Iemolo Francesco; Castiglia Laura; Hachinski Vladimir; Caruso Calogero

    2009-01-01

    Abstract The concept of Vascular Dementia (VaD) has been recognized for over a century, but its definition and diagnostic criteria remain unclear. Conventional definitions identify the patients too late, miss subjects with cognitive impairment short of dementia, and emphasize consequences rather than causes, the true bases for treatment and prevention. We should throw out current diagnostic categories and describe cognitive impairment clinically and according to commonly agreed instruments th...

  14. Update on Vascular Dementia.

    Science.gov (United States)

    Khan, Ayesha; Kalaria, Raj N; Corbett, Anne; Ballard, Clive

    2016-09-01

    Vascular dementia (VaD) is a major contributor to the dementia syndrome and is described as having problems with reasoning, planning, judgment, and memory caused by impaired blood flow to the brain and damage to the blood vessels resulting from events such as stroke. There are a variety of etiologies that contribute to the development of vascular cognitive impairment and VaD, and these are often associated with other dementia-related pathologies such as Alzheimer disease. The diagnosis of VaD is difficult due to the number and types of lesions and their locations in the brain. Factors that increase the risk of vascular diseases such as stroke, high blood pressure, high cholesterol, and smoking also raise the risk of VaD. Therefore, controlling these risk factors can help lower the chances of developing VaD. This update describes the subtypes of VaD, with details of their complex presentation, associated pathological lesions, and issues with diagnosis, prevention, and treatment. PMID:27502303

  15. Vascular Cambium Development

    Science.gov (United States)

    Nieminen, Kaisa; Blomster, Tiina; Helariutta, Ykä; Mähönen, Ari Pekka

    2015-01-01

    Secondary phloem and xylem tissues are produced through the activity of vascular cambium, the cylindrical secondary meristem which arises among the primary plant tissues. Most dicotyledonous species undergo secondary development, among them Arabidopsis. Despite its small size and herbaceous nature, Arabidopsis displays prominent secondary growth in several organs, including the root, hypocotyl and shoot. Together with the vast genetic resources and molecular research methods available for it, this has made Arabidopsis a versatile and accessible model organism for studying cambial development and wood formation. In this review, we discuss and compare the development and function of the vascular cambium in the Arabidopsis root, hypocotyl, and shoot. We describe the current understanding of the molecular regulation of vascular cambium and compare it to the function of primary meristems. We conclude with a look at the future prospects of cambium research, including opportunities provided by phenotyping and modelling approaches, complemented by studies of natural variation and comparative genetic studies in perennial and woody plant species. PMID:26078728

  16. Standard metrics for a plug-and-play tracker

    Science.gov (United States)

    Antonisse, Jim; Young, Darrell

    2012-06-01

    The Motion Imagery Standards Board (MISB) has previously established a metadata "micro-architecture" for standards-based tracking. The intent of this work is to facilitate both the collaborative development of competent tracking systems, and the potentially distributed and dispersed execution of tracker system components in real-world execution environments. The approach standardizes a set of five quasi-sequential modules in image-based tracking. However, in order to make the plug-and-play architecture truly useful we need metrics associated with each module (so that, for instance, a researcher who "plugs in" a new component can ascertain whether he/she did better or worse with the component). This paper proposes the choice of a new, unifying set of metrics based on an informationtheoretic approach to tracking, which the MISB is nominating as DoD/IC/NATO standards.

  17. Fissures and boreholes plugging in fractured geologic deposits (granites)

    International Nuclear Information System (INIS)

    This report gives the results of bench-scale experiments and field tests, destined to describe the bentonite behavior in fractured scale models and in boreholes, and to allow to study the rock weathering phenomenons under specific conditions. Dry and compact bentonite, used for exploratory drilling plugging, in crystalline rock deposits and in contact with groundwater, show hydration, swelling and mobility properties with penetration in conducting fractures. The purpose of this work is to define the procedure of clay weathering after the swelling phase, under groundwater circulation effect, to estimate plugs longevity. This study is prepared for the European Atomic Energy Community cost-sharing research program on radioactive waste management and disposal. 63 refs., 100 figs., 30 tabs., 17 plates

  18. Strength and stability of microbial plugs in porous media

    Energy Technology Data Exchange (ETDEWEB)

    Sarkar, A.K. [NIPER/BDM-Oklahoma, Inc., Bartlesville, OK (United States); Sharma, M.M.; Georgiou, G. [Univ. of Texas, Austin, TX (United States)

    1995-12-31

    Mobility reduction induced by the growth and metabolism of bacteria in high-permeability layers of heterogeneous reservoirs is an economically attractive technique to improve sweep efficiency. This paper describes an experimental study conducted in sandpacks using an injected bacterium to investigate the strength and stability of microbial plugs in porous media. Successful convective transport of bacteria is important for achieving sufficient initial bacteria distribution. The chemotactic and diffusive fluxes are probably not significant even under static conditions. Mobility reduction depends upon the initial cell concentrations and increase in cell mass. For single or multiple static or dynamic growth techniques, permeability reduction was approximately 70% of the original permeability. The stability of these microbial plugs to increases in pressure gradient and changes in cell physiology in a nutrient-depleted environment needs to be improved.

  19. Polymer grouts for plugging lost circulation in geothermal wells.

    Energy Technology Data Exchange (ETDEWEB)

    Galbreath, D. (Green Mountain International, Waynesvile, NC); Mansure, Arthur James; Bauer, Stephen J.

    2004-12-01

    We have concluded a laboratory study to evaluate the survival potential of polymeric materials used for lost circulation plugs in geothermal wells. We learned early in the study that these materials were susceptible to hydrolysis. Through a systematic program in which many potential chemical combinations were evaluated, polymers were developed which tolerated hydrolysis for eight weeks at 500 F. The polymers also met material, handling, cost, and emplacement criteria. This screening process identified the most promising materials. A benefit of this work is that the components of the polymers developed can be mixed at the surface and pumped downhole through a single hose. Further strength testing is required to determine precisely the maximum temperature at which extrusion through fractures or voids causes failure of the lost circulation plug.

  20. Development of port plug handling tractor for ITER

    International Nuclear Information System (INIS)

    The neutron shield plug installed into the horizontal port of ITER (International Thermonuclear Experimental Reactor) vacuum vessel is a heavy component, which mainly consists of stainless steel and cooling water. It has a typical size of 2.3 m x 1.9 m x 3.6 m, and its weight is assumed to be around 40 tons. Development of the remote handling system of the port plug is a key technology for ITER port maintenance because high positioning accuracy is required in spite of narrow handling space. In order to overcome this problem, design and manufacturing of a 1/2.5-scaled mockup of the handling machine has been performed. (author)

  1. Plug and Process Loads Capacity and Power Requirements Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Sheppy, M.; Gentile-Polese, L.

    2014-09-01

    This report addresses gaps in actionable knowledge that would help reduce the plug load capacities designed into buildings. Prospective building occupants and real estate brokers lack accurate references for plug and process load (PPL) capacity requirements, so they often request 5-10 W/ft2 in their lease agreements. Limited initial data, however, suggest that actual PPL densities in leased buildings are substantially lower. Overestimating PPL capacity leads designers to oversize electrical infrastructure and cooling systems. Better guidance will enable improved sizing and design of these systems, decrease upfront capital costs, and allow systems to operate more energy efficiently. The main focus of this report is to provide industry with reliable, objective third-party guidance to address the information gap in typical PPL densities for commercial building tenants. This could drive changes in negotiations about PPL energy demands.

  2. Are Batteries Ready for Plug-in Hybrid Buyers?

    OpenAIRE

    Axsen, Jonn; Kurani, Kenneth S; Burke, Andy

    2009-01-01

    The notion persists that battery technology and cost remain as barriers to commercialization of electric-drive passenger vehicles. Within the context of starting a market for plug-in hybrid electric vehicles (PHEVs), we explore two aspects of the purported problem: (1) PHEV performance goals and (2) the abilities of present and near-term battery chemistries to meet the resulting technological requirements. We summarize evidence stating that battery technologies do not meet the requirements th...

  3. Electricity Grid: Impacts of Plug-In Electric Vehicle Charging

    OpenAIRE

    Yang, Christopher; McCarthy, Ryan

    2009-01-01

    Concerns regarding air pollution, energy dependence, and, increasingly, climate change continue to motivate the search for new transportation solutions. Much of the focus is on light-duty vehicles, as they account for approximately 60% of transportation energy use and greenhouse gas (GHG) emissions. Battery-powered, electric-drive vehicles (EVs), such as plug-in hybrid electric vehicles (PHEVs) and battery electric vehicles (BEVs), are among the most promising of the advanced vehicle and fuel...

  4. Mesh Plug Repair of Inguinal Hernia; Single Surgeon Experience

    Directory of Open Access Journals (Sweden)

    Ahmet Serdar Karaca

    2013-10-01

    Full Text Available Aim: Mesh repair of inguinal hernia repairs are shown to be an effective and reliable method. In this study, a single surgeon%u2019s experience with plug-mesh method performs inguinal hernia repair have been reported. Material and Method: 587 patients with plug-mesh repair of inguinal hernia, preoperative age, body / mass index, comorbid disease were recorded in terms of form. All of the patients during the preoperative and postoperative hernia classification of information, duration of operation, antibiotics, perioperative complications, and later, the early and late postoperative complications, infection, recurrence rates and return to normal daily activity, verbal pain scales in terms of time and postoperative pain were evaluated. Added to this form of long-term pain ones. The presence of wound infection was assessed by the presence of purulent discharge from the incision. Visual analog scale pain status of the patients was measured. Results: 587 patients underwent repair of primary inguinal hernia mesh plug. One of the patients, 439 (74% of them have adapted follow-ups. Patients%u2019 ages ranged from 18-86. Was calculated as the mean of 47±18:07. Follow-up period of the patients was found to be a minimum of 3 months, maximum 55 months. Found an average of 28.2±13.4 months. Mean duration of surgery was 35.07±4.00 min (min:22mn-max:52mn, respectively. When complication rates of patients with recurrence in 2 patients (0.5%, hematoma development (1.4% in 6 patients, the development of infection in 11 patients (2.5% and long-term groin pain in 4 patients (0.9% appeared. Discussion: In our experience, the plug-mesh repair of primary inguinal hernia repair safe, effective low recurrence and complication rates can be used.

  5. AP1000 Features Prevent Potential Containment Recirculation Screen Plugging

    International Nuclear Information System (INIS)

    This paper presents the results of plant design development and evaluations that demonstrate that the AP1000 plant is not subject to potential containment recirculation screen plugging following a loss-of-coolant-accident (LOCA). Following a LOCA in a pressurized water reactor, it is necessary to recirculate water from the containment back into the reactor to maintain long term core cooling. The AP1000 utilizes passive safety systems to provide containment recirculation for long term core cooling following a LOCA. The AP1000 also has non-safety pumps which provide a backup means of providing recirculation. Screens are provided around the recirculation pipes to prevent debris from blocking recirculation flow and core cooling passages. Debris may be generated by the LOCA blowdown from insulation and coatings used inside containment. Even with effective cleanliness programs, there may be some resident debris such as dust and dirt. The potential for plugging the recirculation screens is a current PWR licensing issue. The AP1000 design provides inherent advantages with respect to the potential plugging of containment recirculation screens. These characteristics include prevention of fibrous debris generation, improved debris settling and improved recirculation screen design. Debris settling analysis demonstrates that failure of coatings does not result in debris being transported to the screens before it settles to the floor. Additional analysis also shows that the plant can tolerate conservative amounts of resident debris being transported to the screens. The AP1000 significantly reduces the probability of plugging the containment recirculation screens and significantly reduces inspection and maintenance of coatings used inside containment. (authors)

  6. Plug-In Electric Vehicle Handbook for Workplace Charging Hosts

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-08-01

    Plug-in electric vehicles (PEVs) have immense potential for increasing the country's energy, economic, and environmental security, and they will play a key role in the future of U.S. transportation. By providing PEV charging at the workplace, employers are perfectly positioned to contribute to and benefit from the electrification of transportation. This handbook answers basic questions about PEVs and charging equipment, helps employers assess whether to offer workplace charging for employees, and outlines important steps for implementation.

  7. Are batteries ready for plug-in hybrid buyers?

    OpenAIRE

    Axsen, Jonn; Kurani, Kenneth S; Burke, Andrew

    2008-01-01

    The notion persists that battery technology and cost remain as barriers to commercialization of electric-drive passenger vehicles. Within the context of starting a market for plug-in hybrid electric vehicles (PHEVs), we explore two aspects of the purported problem: (1) PHEV performance goals and (2) the abilities of present and near-term battery chemistries to meet the resulting technological requirements. We summarize evidence stating that battery technologies do not meet the requirements th...

  8. Are Batteries Ready for Plug-in Hybrid Buyers?

    OpenAIRE

    Axsen, Jonn; Burke, Andy; Kurani, Kenneth S

    2010-01-01

    The notion persists that battery technology and cost remain as barriers to commercialization of electric-drive passenger vehicles. Within the context of starting a market for plug-in hybrid electric vehicles (PHEVs), we explore two aspects of the purported problem: (1) PHEV performance goals and (2) the abilities of present and near-term battery chemistries to meet the resulting technological requirements. We summarize evidence stating that battery technologies do not meet the requirements t...

  9. Kaolinite Mobilisation in Sandstone:Pore Plugging vs. Suspended Particles

    OpenAIRE

    Rosenbrand, Esther; Fabricius, Ida Lykke; Kets, Frans

    2013-01-01

    The effect of temperature and salinity on sandstone permeability is critical to the feasibility of heat storage in geothermal aquifers. Permeability reduction has been observed in Berea sandstone when the salinity of the pore water is reduced as well as when the sample is heated. Several authors suggest that this effect is due to kaolinite clay mobilisation from the quartz grain surface; the mobilised particles subsequently plug the pore throats and reduce the permeability irreversibly. The e...

  10. Controlling droplet incubation using close-packed plug flow

    OpenAIRE

    Mary, Pascaline; Abate, Adam R.; Agresti, Jeremy J.; Weitz, David A.

    2011-01-01

    Controlling droplet incubation is critical for droplet-based microfluidic applications; however, current techniques are either of limited precision or place strict limits on the incubation times that can be achieved. Here, we present a simple technique to control incubation time by exploiting close-packed plug flow. In contrast to other techniques, this technique is applicable to very short and very long incubation times.

  11. Experimental Investigation of Near-Borehole Crack Plugging with Bentonite

    Science.gov (United States)

    Upadhyay, R. A.; Islam, M. N.; Bunger, A.

    2015-12-01

    The success of the disposal of nuclear waste in a deep borehole (DBH) is determined by the integrity of the components of the borehole plug. Bentonite clay has been proposed as a key plugging material, and its effectiveness depends upon its penetration into near-borehole cracks associated with the drilling process. Here we present research aimed at understanding and maximizing the ability of clay materials to plug near-borehole cracks. A device was constructed such that the borehole is represented by a cylindrical chamber, and a near-borehole crack is represented by a slot adjacent to the center chamber. The experiments consist of placing bentonite clay pellets into the center chamber and filling the entire cavity with distilled water so that the pellets hydrate and swell, intruding into the slot because the cell prohibits swelling in the vertical direction along the borehole. Results indicate that the bentonite clay pellets do not fully plug the slot. We propose a model where the penetration is limited by (1) the free swelling potential intrinsic to the system comprised of the bentonite pellets and the hydrating fluid and (2) resisting shear force along the walls of the slot. Narrow slots have a smaller volume for the clay to fill than wider slots, but wider slots present less resistive force to clay intrusion. These two limiting factors work against each other, leading to a non-monotonic relationship between slot width and intrusion length. Further experimental results indicate that the free swelling potential of bentonite clay pellets depends on pellet diameter, "container" geometry, and solution salinity. Smaller diameter pellets possess more relative volumetric expansion than larger diameter pellets. The relative expansion of the clay also appears to decrease with the container size, which we understand to be due to the increased resistive force provided by the container walls. Increasing the salinity of the solution leads to a dramatic decrease in the clay

  12. Selecting a Control Strategy for Plug and Process Loads

    Energy Technology Data Exchange (ETDEWEB)

    Lobato, C.; Sheppy, M.; Brackney, L.; Pless, S.; Torcellini, P.

    2012-09-01

    Plug and Process Loads (PPLs) are building loads that are not related to general lighting, heating, ventilation, cooling, and water heating, and typically do not provide comfort to the building occupants. PPLs in commercial buildings account for almost 5% of U.S. primary energy consumption. On an individual building level, they account for approximately 25% of the total electrical load in a minimally code-compliant commercial building, and can exceed 50% in an ultra-high efficiency building such as the National Renewable Energy Laboratory's (NREL) Research Support Facility (RSF) (Lobato et al. 2010). Minimizing these loads is a primary challenge in the design and operation of an energy-efficient building. A complex array of technologies that measure and manage PPLs has emerged in the marketplace. Some fall short of manufacturer performance claims, however. NREL has been actively engaged in developing an evaluation and selection process for PPLs control, and is using this process to evaluate a range of technologies for active PPLs management that will cap RSF plug loads. Using a control strategy to match plug load use to users' required job functions is a huge untapped potential for energy savings.

  13. Post-traumatic bronchial mucus plug leading to pneumonectomy

    Directory of Open Access Journals (Sweden)

    Khan M.S

    2012-01-01

    Full Text Available Background: Blunt trauma of the chest is not uncommon these days. By far, the most important cause of significant blunt chest trauma is motor vehicle accidents. Pedestrians struck by vehicles, falls from height, blast injuries and acts of violence are other causative mechanisms. Most of the blunt trauma cases need no operative intervention and can be managed by supportive procedures. Aim: We present a case of a 10-year old boy who had blunt trauma to chest due to fall from height. Findings: The patient was in respiratory distress and developed surgical emphysema and pneumothorax on the left side. He was managed by putting in a chest drain on the left side. Patient improved and was discharged .He again developed respiratory distress 15 days later. On bronchoscopic examination, an obstruction was found just distal to the carina in the left bronchus. Several futile attempts were made to retrieve the obstructing material. Hence, mucus plug was removed through left bronchotomy. There was no improvement in the ventilation of the left lung for 7 days. Bronchoscopic suction was done. All the measures failed and the lung remained collapsed. Patient underwent pneumonectomy as the last treatment option available in our hospital. At the time of reporting this case, patient was doing well. Conclusion: Chest physiotherapy helps in reducing lung collapse. If patient is reluctant to chest physiotherapy and coughing, it can lead to accumulation of respiratory secretions and formation of mucus plug. This mucus plug can cause collapse of the lung and ill consequences.

  14. Formation of hydrate plug within rectangular natural gas passage

    Energy Technology Data Exchange (ETDEWEB)

    Seong, K.; Song, M.H.; Ahn, J.H.; Yoo, K.S. [Dong Guk Univ., Joong-ku, Seoul (Korea, Republic of)

    2008-07-01

    Oil and gas reservoirs in off-shore shallow areas are being depleted. At the same time, the industry is expanding its production sites into deeper waters resulting in higher pressure and lower temperature and more isolated locations. In response, connecting pipelines have been extended, but because of these pressure, temperature and distance changes in pipelines, a more favorable condition for hydrate formation is created, making the problem of flow assurance more critical for safe and economic operations at deep off-shore oil and gas production sites. Another challenge in flow assurance lies in hydrate formation and potential blockage due to hydrate plugs in gas pipelines, where no free water phase is present. This paper presented an experimental study that examined the formation and the growth of hydrates from a gas mixture of methane and propane with different moisture concentrations. The hydrates were formed in a rectangular passage cooled to temperatures below equilibrium hydrate formation temperature. The paper described the experimental procedure and apparatus that was designed and fabricated for the study. A schematic layout of the hydrate formation and plug test experimental apparatus was illustrated. The paper also described the results of two sets of experiments that were conducted. It was concluded that with enough moisture content, hydrates formed without a fresh water phase under equilibrium conditions. It was also concluded that the results of the study could be used in verifying numerical models developed to predict hydrate plugging of natural gas pipelines. 4 refs., 6 figs.

  15. Geochemical factors in borehole-shaft plug longevity

    International Nuclear Information System (INIS)

    Geochemical investigations that address factors controlling the longevity of repository sealing materials in a geochemical environment are discussed. Studies are being made of cement-based materials as major candidates for seals for borehole plugging, and shaft and tunnel sealing in certain potential repository environments. Factors controlling the extent of attainment of equilibrium of the plug components with time and the rate of approach to a state of stable equilibrium of the plug component chemical subsystem within the total system are discussed. The effect of these factors on changes in physical, mechanical and thermal properties of a seal system, and the consequent effectiveness of the seal in preventing transport of radioactive waste species are the dominant features to be determined. Laboratory experiments on the effects of anticipated temperature, pressure, and environmental factors (including chemical composition and specific rock type) are described. Thermodynamic studies are used to determine the potentially stable reaction products under conditions similar to those anticipated for the repository boreholes, shafts, and tunnels during and after the operating stage. Multitemperature reaction series are studied, and reaction kinetics are investigated for the purpose of predicting the course of likely reactions. Detailed studies of permeability, diffusion, and interfacial properties and chemical and microphase characterization of the products of experiments are carried out. Characterization studies of old and ancient cements, mortars, and concretes and prototype man-made seal materials are performed to further assess the factors associated with longevity

  16. End plug for fuel rod and welding method therefor

    International Nuclear Information System (INIS)

    An end plug of a fuel rod comprises a pressure-insertion portion having a diameter somewhat greater than the inner diameter of a fuel cladding tube and a welding portion having a diameter substantially the same as the outer diameter of the cladding tube. A V-shaped recess having an outer diameter smaller than the greatest outer diameter of the pressure-insertion portion is formed over the entire circumferential surface of the outer circumference of the connection portion of the pressure-insertion portion and the welding portion. The pressure-insertion portion of the end plug is inserted to the end of the cladding tube till the end of the cladding tube abuts against the inclined surface of the V-shaped recess. The abutting surfaces of the end plug and the cladding tube are subjected to resistance welding in this state. The inner portion bulged from the inclined surface of the V-shaped recess is filled in the recess in a molten state. Lowering of temperature of the cladding tube in the vicinity of the welded portion is decreased by γ heat during reactor operation. Accordingly, lowering of ductility of the cladding tube and degradation of material of the welded region due to segregation of hydrogen in the cladding tube can be suppressed. (I.N.)

  17. Borehole plugging test activities in southeastern New Mexico

    International Nuclear Information System (INIS)

    Conclusions from these studies indicated that borehole seals with effective permeabilities on the order of tens of darcies would result in doses to maximally exposed individuals of less than 0.01% of natural background. In addition to overall assessments, techniques have been developed to evaluate the effectiveness of a plug/formation system to block fluid flow along the axis of the borehole. These techniques allow the characterization of the flow region within or surrounding a plug. They have been applied to results from tests in which flow was measured around an in situ plug. Current emphasis has been on evaluation of cementitious grouts. Grout mixes with expansive cement have been developed using various additives and both brines and fresh water. These mixes have been tailored to specific rocks for use in field tests. The characteristics (e.g., permeability bond strength) of these mixes and associated rocks have been determined in the laboratory and then compared with in situ performance. Studies of grout feasibility have been coupled with strategies for assessing long-term stability

  18. [How Treatable is Vascular Dementia?].

    Science.gov (United States)

    Mori, Etsuro

    2016-04-01

    Vascular dementia is an umbrella term, encompassing the pathological changes in the brain due to cerebrovascular disease that result in dementia. Vascular dementia is the second most common form of dementia, after Alzheimer's disease. In this paper, I outline the concept of vascular dementia, the key aspects of the disease that are yet to be clarified, and the current status of clinical trials. Assessing these factors, I discuss how treatable vascular dementia presently is. Use of the term'vascular dementia'is riddled with uncertainties regarding disease classification, and non-standardized diagnostic criteria. There are difficulties in determining the exact relationship between cerebrovascular pathology and cognitive impairment. The comorbid effects of Alzheimer's pathology in some individuals also present an obstacle to reliable clinical diagnosis, and hinder research into effective management approaches. Vascular dementia is preventable and treatable, as there are established primary and secondary prevention measures for the causative cerebrovascular diseases, such as vascular risk factor intervention, antiplatelet therapy, and anticoagulation, amongst others. However, unlike Alzheimer's disease, there are no established symptomatic treatments for vascular dementia. Clinical trials of cholinesterase inhibitors and memantine indicate that they produce small cognitive benefits in patients with vascular dementia, though the exact clinical significance of these is uncertain. Data are insufficient to support the widespread use of these drugs in vascular dementia. Rehabilitation and physical and cognitive exercise may be beneficial, but evidence of cognitive benefit and relief of neuropsychiatric symptoms due to exercise is lacking. PMID:27056862

  19. The Vascular Depression Hypothesis: Mechanisms Linking Vascular Disease with Depression

    OpenAIRE

    Taylor, Warren D.; Aizenstein, Howard J.; Alexopoulos, George S.

    2013-01-01

    The ‘Vascular Depression’ hypothesis posits that cerebrovascular disease may predispose, precipitate, or perpetuate some geriatric depressive syndromes. This hypothesis stimulated much research that has improved our understanding of the complex relationships between late-life depression (LLD), vascular risk factors, and cognition. Succinctly, there are well-established relationships between late-life depression, vascular risk factors, and cerebral hyperintensities, the radiological hallmark o...

  20. Optimal control of a repowered vehicle: Plug-in fuel cell against plug-in hybrid electric powertrain

    International Nuclear Information System (INIS)

    This paper describes two different powertrain configurations for the repowering of a conventional vehicle, equipped with an internal combustion engine (ICE). A model of a mid-sized ICE-vehicle is realized and then modified to model both a parallel plug-in hybrid electric powertrain and a proton electrolyte membrane (PEM) fuel cell (FC) hybrid powertrain. The vehicle behavior under the application of an optimal control algorithm for the energy management is analyzed for the different scenarios and results are compared

  1. Abdominal Vascular Catastrophes.

    Science.gov (United States)

    Singh, Manpreet; Koyfman, Alex; Martinez, Joseph P

    2016-05-01

    Abdominal vascular catastrophes are among the most challenging and time sensitive for emergency practitioners to recognize. Mesenteric ischemia remains a highly lethal entity for which the history and physical examination can be misleading. Laboratory tests are often unhelpful, and appropriate imaging must be quickly obtained. A multidisciplinary approach is required to have a positive impact on mortality rates. Ruptured abdominal aortic aneurysm likewise may present in a cryptic fashion. A specific type of ruptured aneurysm, the aortoenteric fistula, often masquerades as the more common routine gastrointestinal bleed. The astute clinician recognizes that this is a more lethal variant of gastrointestinal hemorrhage. PMID:27133247

  2. Microfluidic Technology in Vascular Research

    Directory of Open Access Journals (Sweden)

    A. D. van der Meer

    2009-01-01

    Full Text Available Vascular cell biology is an area of research with great biomedical relevance. Vascular dysfunction is involved in major diseases such as atherosclerosis, diabetes, and cancer. However, when studying vascular cell biology in the laboratory, it is difficult to mimic the dynamic, three-dimensional microenvironment that is found in vivo. Microfluidic technology offers unique possibilities to overcome this difficulty. In this review, an overview of the recent applications of microfluidic technology in the field of vascular biological research will be given. Examples of how microfluidics can be used to generate shear stresses, growth factor gradients, cocultures, and migration assays will be provided. The use of microfluidic devices in studying three-dimensional models of vascular tissue will be discussed. It is concluded that microfluidic technology offers great possibilities to systematically study vascular cell biology with setups that more closely mimic the in vivo situation than those that are generated with conventional methods.

  3. A mating plug and male mate choice in Drosophila hibisci Bock.

    Science.gov (United States)

    Polak; Starmer; Barker

    1998-10-01

    The functional significance of mating plugs and their relation to male mating behaviour in insects are obscure. In Drosophila hibisci, we describe a firm, gelatinous, mating plug that fills the entire uterus at copulation, and evaluate two nonmutually exclusive hypotheses for the plug's function: (1) retention of sperm near the openings of the sperm storage organs and (2) inhibition of further matings. Unlike full-sized plugs, smaller plugs produced by previously mated males failed to retain sperm at the anterior end of the uterus, indicating that full-sized plugs prevent sperm backflow away from female storage organs. Sexually mature males failed to copulate with previously mated, young females, suggesting that the plug may also deter rival matings. In newly emerged females, the plug remains within the uterus for up to 4 days after copulation, but in mature females, the plug and ejaculate are expelled whenever the next mature oocyte descends into the uterus from the common oviduct, which may be soon after copulation. Males remained in copula significantly longer with mature females, perhaps to compensate for this greater likelihood of ejaculate expulsion. Males showed a mating preference for young virgins over older virgin and nonvirgin females. This unusual mating preference may confer fertility benefits made available through the effectiveness of the plug in reducing sperm competition. Copyright 1998 The Association for the Study of Animal Behaviour. PMID:9790703

  4. MRI evaluation of vascular dementia

    Institute of Scientific and Technical Information of China (English)

    Yicheng Liu; Hongxing Zhang; Wei Huang; Wenjun Wan; Hongfen Peng

    2006-01-01

    OBJECTTVE: To explain the association between vascular dementia and the cranial MRI manifestations, and recognize the value of cranial MRI in the early diagnosis of vascular dementia and the assessment of disease conditions.DATA SOURCES: Pubmed database was searched to identify articles about the cranial MRI manifestations of patients with vascular dementia published in English from January 1992 to June 2006 by using the key words of "MRI, vascular dementia". Others were collected by searching the name of journals and title of articles in the Chinese full-text journal database.STUDY SELECTTON: The collected articles were primarily checked, those correlated with the cranial MRI manifestations of patients with vascular dementia were selected, while the obviously irrelative ones were excluded, and the rest were retrieved manually, the full-texts were searched.DATA EXTRACTION: Totally 255 articles were collected, 41 of them were involved, and the other 214 were excluded.DATA SYNTHESIS: MRI can be taken as one of the effective methods for the early diagnosis and disease evaluation of vascular dementia. White matter lesions are the important risk factors of vascular dementia.Vascular dementia is accompanied by the atrophy of related brain sites, but further confirmation is needed to investigate whether there is significant difference. MRI can be used to quantitatively investigate the infarcted sites and sizes of patients with vascular dementia after infarction, but there is still lack of systematic investigation on the association of the infarcted sites and sizes with the cognitive function of patients with vascular dementia.CONCLUSTON: Cranial MRI can detect the symptoms of vascular dementia at early period, so that corresponding measures can be adopted to prevent and treat vascular dementia in time.

  5. Vascular Remodeling in Experimental Hypertension

    Directory of Open Access Journals (Sweden)

    Norma R. Risler

    2005-01-01

    Full Text Available The basic hemodynamic abnormality in hypertension is an increased peripheral resistance that is due mainly to a decreased vascular lumen derived from structural changes in the small arteries wall, named (as a whole vascular remodeling. The vascular wall is an active, flexible, and integrated organ made up of cellular (endothelial cells, smooth muscle cells, adventitia cells, and fibroblasts and noncellular (extracellular matrix components, which in a dynamic way change shape or number, or reorganize in response to physiological and pathological stimuli, maintaining the integrity of the vessel wall in physiological conditions or participating in the vascular changes in cardiovascular diseases such as hypertension. Research focused on new signaling pathways and molecules that can participate in the mechanisms of vascular remodeling has provided evidence showing that vascular structure is not only affected by blood pressure, but also by mechanisms that are independent of the increased pressure. This review will provide an overview of the evidence, explaining some of the pathophysiologic mechanisms participating in the development of the vascular remodeling, in experimental models of hypertension, with special reference to the findings in spontaneously hypertensive rats as a model of essential hypertension, and in fructose-fed rats as a model of secondary hypertension, in the context of the metabolic syndrome. The understanding of the mechanisms producing the vascular alterations will allow the development of novel pharmacological tools for vascular protection in hypertensive disease.

  6. Spinal vascular malformations

    Energy Technology Data Exchange (ETDEWEB)

    Krings, Timo [University Hospital Aachen, Department of Neuroradiology, Aachen (Germany); University Hospital Aachen, Department of Neurosurgery, Aachen (Germany); Mull, Michael; Thron, Armin [University Hospital Aachen, Department of Neuroradiology, Aachen (Germany); Gilsbach, Joachim M. [University Hospital Aachen, Department of Neurosurgery, Aachen (Germany)

    2005-02-01

    Spinal vascular malformations are rare diseases that consist of true inborn cavernomas and arteriovenous malformations (including perimedullary fistulae, glomerular and juvenile AVMs) and presumably acquired dural arteriovenous fistulae. This review article gives an overview of the imaging features both on MRI and angiography, the differential diagnoses, the clinical symptomatology and the potential therapeutic approaches to these diseases. It is concluded that MRI is the diagnostic modality of first choice in suspected spinal vascular malformation and should be complemented by selective spinal angiography. Treatment in symptomatic patients offers an improvement in the prognosis, but should be performed in specialized centers. Patients with spinal cord cavernomas and perimedullary fistulae type I are surgical candidates. Dural arteriovenous fistulae can either be operated upon or can be treated by an endovascular approach, the former being a simple, quick and secure approach to obliterate the fistula, while the latter is technically demanding. In spinal arteriovenous malformations, the endovascular approach is the method of first choice; in selected cases, a combined therapy might be sensible. (orig.)

  7. Spinal vascular malformations

    International Nuclear Information System (INIS)

    Spinal vascular malformations are rare diseases that consist of true inborn cavernomas and arteriovenous malformations (including perimedullary fistulae, glomerular and juvenile AVMs) and presumably acquired dural arteriovenous fistulae. This review article gives an overview of the imaging features both on MRI and angiography, the differential diagnoses, the clinical symptomatology and the potential therapeutic approaches to these diseases. It is concluded that MRI is the diagnostic modality of first choice in suspected spinal vascular malformation and should be complemented by selective spinal angiography. Treatment in symptomatic patients offers an improvement in the prognosis, but should be performed in specialized centers. Patients with spinal cord cavernomas and perimedullary fistulae type I are surgical candidates. Dural arteriovenous fistulae can either be operated upon or can be treated by an endovascular approach, the former being a simple, quick and secure approach to obliterate the fistula, while the latter is technically demanding. In spinal arteriovenous malformations, the endovascular approach is the method of first choice; in selected cases, a combined therapy might be sensible. (orig.)

  8. Pulmonary vascular diseases.

    Science.gov (United States)

    Mélot, C; Naeije, R

    2011-04-01

    Diseases of the pulmonary vasculature are a cause of increased pulmonary vascular resistance (PVR) in pulmonary embolism, chronic thromboembolic pulmonary hypertension (CTEPH), and pulmonary arterial hypertension or decreased PVR in pulmonary arteriovenous malformations on hereditary hemorrhagic telangiectasia, portal hypertension, or cavopulmonary anastomosis. All these conditions are associated with a decrease in both arterial PO2 and PCO2. Gas exchange in pulmonary vascular diseases with increased PVR is characterized by a shift of ventilation and perfusion to high ventilation-perfusion ratios, a mild to moderate increase in perfusion to low ventilation-perfusion ratios, and an increased physiologic dead space. Hypoxemia in these patients is essentially explained by altered ventilation-perfusion matching amplified by a decreased mixed venous PO2 caused by a low cardiac output. Hypocapnia is accounted for by hyperventilation, which is essentially related to an increased chemosensitivity. A cardiac shunt on a patent foramen ovale may be a cause of severe hypoxemia in a proportion of patients with pulmonary hypertension and an increase in right atrial pressure. Gas exchange in pulmonary arteriovenous malformations is characterized by variable degree of pulmonary shunting and/or diffusion-perfusion imbalance. Hypocapnia is caused by an increased ventilation in relation to an increased pulmonary blood flow with direct peripheral chemoreceptor stimulation by shunted mixed venous blood flow. PMID:23737196

  9. Plugging margin evaluation considering the fouling of shell-and-tube heat exchanger

    International Nuclear Information System (INIS)

    As operating time of heat exchangers progresses, fouling generated by water-borne deposits increases, number of tube plugging increases, and thermal performance decreases. The fouling and plugging of tubes are known to interfere with normal flow characteristics and reduce thermal efficiencies of heat exchangers. This paper describes the plugging margin evaluation method which can reflect the current fouling level developed in this study. To develop the plugging margin evaluation methods for heat exchangers, fouling factor was introduced based on the ASME O and M codes and TEMA standards. For the purpose of verifying the plugging margin evaluation methods, the fouling and plugging margin evaluations were performed for a component cooling heat exchanger in a nuclear power plant

  10. An overview of vascular closure devices: What every radiologist should know

    International Nuclear Information System (INIS)

    Haemostatic devices can be categorised according to their mechanism of action into three main types; namely pressure devices, topical haemostatic pads and vascular closure devices (VCD). Of these three categories, it is the development of VCDs that revolutionised management of endovascular procedures. Currently available VCDs fall into three major classes, those that use a collagen plug, those that use clips and those that perform suture closure at the arteriotomy site. This article provides a comprehensive review of the all three classes with examples of commercially available devices.

  11. Airfoil cooling hole plugging by combustion gas impurities of the type found in coal derived fuels

    Science.gov (United States)

    Deadmore, D. L.; Lowell, C. E.

    1979-01-01

    The plugging of airfoil cooling holes by typical coal-derived fuel impurities was evaluated using doped combustion gases in an atmospheric pressure burner rig. Very high specific cooling air mass flow rates reduced or eliminated plugging. The amount of flow needed was a function of the composition of the deposit. It appears that plugging of film-cooled holes may be a problem for gas turbines burning coal-derived fuels.

  12. Evaluation of Down Hole Seal Plugs Used in Drilling & Well Operations

    OpenAIRE

    Graver, Steinar

    2010-01-01

    As the demand for hydrocarbons increases, the oil companies are forced to start oil and gas exploration in complicated and remote fields. When drilling such environment, the requirement for safety, reliability and operational efficiency of down hole tools is vital. An evaluation of different drill pipe convoyed seal plugs is performed with respect to plug features, benefits,operational procedure and limitations. A comparison based on the different plug design and a review of applications for ...

  13. Plugging wells for abandonment: a state-of-the-art study and recommended procedures

    Energy Technology Data Exchange (ETDEWEB)

    Herndon, J.; Smith, D.K.

    1976-09-01

    The state-of-the-art of borehole plugging of abandoned oil wells and the tools and materials used are discussed. Special problems encountered are considered and several case studies are outlined. The special procedures which must be followed if the plugged borehole is to be considered as a repository for radioactive wastes are discussed and special recommendations are made. A state-by-state summary is given of the regulatory requirements for borehole plugging. (JSR)

  14. Plugging wells for abandonment: a state-of-the-art study and recommended procedures

    International Nuclear Information System (INIS)

    The state-of-the-art of borehole plugging of abandoned oil wells and the tools and materials used are discussed. Special problems encountered are considered and several case studies are outlined. The special procedures which must be followed if the plugged borehole is to be considered as a repository for radioactive wastes are discussed and special recommendations are made. A state-by-state summary is given of the regulatory requirements for borehole plugging

  15. Erosion on spark plug electrodes; Funkenerosion an Zuendkerzenelektroden

    Energy Technology Data Exchange (ETDEWEB)

    Rager, J.

    2006-07-01

    Durability of spark plugs is mainly determined by spark gap widening, caused by electrode wear. Knowledge about the erosion mechanisms of spark plug materials is of fundamental interest for the development of materials with a high resistance against electrode erosion. It is therefore crucial to identify those parameters which significantly influence the erosion behaviour of a material. In this work, a reliable and reproducible testing method is presented which produces and characterizes electrode wear under well-defined conditions and which is capable of altering parameters specifically. Endurance tests were carried out to study the dependence of the wear behaviour of pure nickel and platinum on the electrode temperature, gas, electrode gap, electrode diameter, atmospheric pressure, and partial pressure of oxygen. It was shown that erosion under nitrogen is negligible, irrespective of the material. This disproves all common mechanism discussed in the literature explaining material loss of spark plug electrodes. Based on this observation and the variation of the mentioned parameters a new erosion model was deduced. This relies on an oxidation of the electrode material and describes the erosion of nickel and platinum separately. For nickel, electrode wear is caused by the removal of an oxide layer by the spark. In the case of platinum, material loss occurs due to the plasma-assisted formation and subsequent evaporation of volatile oxides in the cathode spot. On the basis of this mechanism a new composite material was developed whose erosion resistance is superior to pure platinum. Oxidation resistant metal oxide particles were added to a platinum matrix, thus leading to a higher erosion resistance of the composite. However, this can be decreased by a side reaction, the separation of oxygen from the metal oxides, which effectively assists the oxidation of the matrix. This reaction can be suppressed by using highly stable oxides, characterized by a large negative Gibbs

  16. Dynamic adaption of vascular morphology

    DEFF Research Database (Denmark)

    Okkels, Fridolin; Jacobsen, Jens Christian Brings

    2012-01-01

    The structure of vascular networks adapts continuously to meet changes in demand of the surrounding tissue. Most of the known vascular adaptation mechanisms are based on local reactions to local stimuli such as pressure and flow, which in turn reflects influence from the surrounding tissue. Here ...

  17. Plug in electric vehicles in smart grids charging strategies

    CERN Document Server

    Rajakaruna, Sumedha; Ghosh, Arindam

    2014-01-01

    This book covers the recent research advancements in the area of charging strategies that can be employed to accommodate the anticipated high deployment of Plug-in Electric Vehicles (PEVs) in smart grids. Recent literature has focused on various potential issues of uncoordinated charging of PEVs and methods of overcoming such challenges. After an introduction to charging coordination paradigms of PEVs, this book will present various ways the coordinated control can be accomplished. These innovative approaches include hierarchical coordinated control, model predictive control, optimal control

  18. Compact Fluorescent Plug-In Ballast-in-a-Socket

    Energy Technology Data Exchange (ETDEWEB)

    Rebecca Voelker

    2001-12-21

    The primary goal of this program was to develop a ballast system for plug-in CFLs (compact fluorescent lamps) that will directly replace standard metal shell, medium base incandescent lampholders (such as Levition No. 6098) for use with portable lamp fixtures, such as floor, table and desk lamps. A secondary goal was to identify a plug-in CFL that is optimized for use with this ballast. This Plug-in CFL Ballastin-a-Socket system will allow fixture manufacturers to easily manufacture CFL-based high-efficacy portable fixtures that provide residential and commercial consumers with attractive, cost-effective, and energy-efficient fixtures for use wherever portable incandescent fixtures are used today. The advantages of this proposed system over existing CFL solutions are that the fixtures can only be used with high-efficacy CFLs, and they will be more attractive and will have lower life-cycle costs than screw-in or adapter-based CFL retrofit solutions. These features should greatly increase the penetration of CFL's into the North American market. Our work has shown that using integrated circuits it is quite feasible to produce a lamp-fixture ballast of a size comparable to the current Edison-screw 3-way incandescent fixtures. As for price points for BIAS-based fixtures, end-users polled by the Lighting Research Institute at RPI indicated that they would pay as much as an additional $10 for a lamp containing such a ballast. The ballast has been optimized to run with a 26 W amalgam triple biax lamp in the base-down position, yet can accept non-amalgam versions of the lamp. With a few part alterations, the ballast can be produced to support 32 W lamps as well. The ballast uses GE's existing L-Comp[1] power topology in the circuit so that the integrated circuit design would be a design that could possibly be used by other CFL and EFL products with minor modifications. This gives added value by reducing cost and size of not only the BIAS, but also possibly other

  19. Electric and plug-in hybrid vehicles advanced simulation methodologies

    CERN Document Server

    Varga, Bogdan Ovidiu; Moldovanu, Dan; Iclodean, Calin

    2015-01-01

    This book is designed as an interdisciplinary platform for specialists working in electric and plug-in hybrid electric vehicles powertrain design and development, and for scientists who want to get access to information related to electric and hybrid vehicle energy management, efficiency and control. The book presents the methodology of simulation that allows the specialist to evaluate electric and hybrid vehicle powertrain energy flow, efficiency, range and consumption. The mathematics behind each electric and hybrid vehicle component is explained and for each specific vehicle the powertrain

  20. A study on thimble plug removal for PWR plants

    Energy Technology Data Exchange (ETDEWEB)

    Song, Dong Soo; Lee, Chang Sup; Lee, Jae Yong; Jun, Hwang Yong [Korea Electric Power Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    The thermal-hydraulic effects of removing the RCC guide thimble plugs are evaluated for 8 Westinghouse type PWR plants in Korea as a part of feasibility study: core outlet loss coefficient, thimble bypass flow, and best estimate flow. It is resulted that the best estimate thimble bypass flow increases about by 2% and the best estimate flow increases approximately by 1.2%. The resulting DNBR penalties can be covered with the current DNBR margin. Accident analyses are also investigated that the dropped rod transient is shown to be limiting and relatively sensitive to bypass flow variation. 8 refs., 5 tabs. (Author)

  1. Shielding analysis for ITER equatorial bio-shield plug

    International Nuclear Information System (INIS)

    ITER equatorial port cell outside bio-shield plug is a place for allowing free personnel access after shutdown which accommodates various sensitive equipment and pipes. To ensure the personnel safety in port cell after shutdown, the distribution of dose rate in port cell was studied. Based on VisualBUS (CAD-Based Multi-Functional 4D Neutronics Simulation System), dose rate calculations were completed in port cell after shutdown. The result showed that dose rates in port cell are still 2 orders of magnitude more than desired limit (10 μSv/h) after one day shutdown. The optimization of bio-shield was needed. (authors)

  2. Plug in electric vehicles in smart grids energy management

    CERN Document Server

    Rajakaruna, Sumedha; Ghosh, Arindam

    2014-01-01

    This book highlights the cutting-edge research on energy management within smart grids with significant deployment of Plug-in Electric Vehicles (PEV). These vehicles not only can be a significant electrical power consumer during Grid to Vehicle (G2V) charging mode, they can also be smartly utilized as a controlled source of electrical power when they are used in Vehicle to Grid (V2G) operating mode. Electricity Price, Time of Use Tariffs, Quality of Service, Social Welfare as well as electrical parameters of the network are all different criteria considered by the researchers when developing

  3. Plug-In Hybrid Vehicle Analysis (Milestone Report)

    Energy Technology Data Exchange (ETDEWEB)

    Markel, T.; Brooker, A.; Gonder, J.; O' Keefe, M.; Simpson, A.; Thornton, M.

    2006-11-01

    NREL's plug-in hybrid electric vehicle (PHEV) analysis activities made great strides in FY06 to objectively assess PHEV technology, support the larger U.S. Department of Energy PHEV assessment effort, and share technical knowledge with the vehicle research community and vehicle manufacturers. This report provides research papers and presentations developed in FY06 to support these efforts. The report focuses on the areas of fuel economy reporting methods, cost and consumption benefit analysis, real-world performance expectations, and energy management strategies.

  4. Component sizing optimization of plug-in hybrid electric vehicles

    International Nuclear Information System (INIS)

    Plug-in hybrid electric vehicles (PHEVs) are considered as one of the most promising means to improve the near-term sustainability of the transportation and stationary energy sectors. This paper describes a methodology for the optimization of PHEVs component sizing using parallel chaos optimization algorithm (PCOA). In this approach, the objective function is defined so as to minimize the drivetrain cost. In addition, the driving performance requirements are considered as constraints. Finally, the optimization process is performed over three different all electric range (AER) and two types of batteries. The results from computer simulation show the effectiveness of the approach and the reduction in drivetrian cost while ensuring the vehicle performance.

  5. Plug in electric vehicles in smart grids integration techniques

    CERN Document Server

    Rajakaruna, Sumedha; Ghosh, Arindam

    2014-01-01

    This book focuses on the state of the art in worldwide research on applying optimization approaches to intelligently control charging and discharging of batteries of Plug-in Electric Vehicles (PEVs) in smart grids. Network constraints, cost considerations, the number and penetration level of PEVs, utilization of PEVs by their owners, ancillary services, load forecasting, risk analysis, etc. are all different criteria considered by the researchers in developing mathematical based equations which represent the presence of PEVs in electric networks. Different objective functions can be defined an

  6. Fiscal year 1996 well plugging and abandonment program Y-12 Plant, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    This report is a synopsis of the progress of the well plugging and abandonment program at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee, from August 1995 through August 1996. A total of 27 wells, piezometers, and borings were plugged and abandoned during the period of time covered in this report. All wells and borings were plugged and abandoned in accordance with the Monitoring Well Plugging and Abandonment Plan for the U.S. Department of Energy, Y-12 Plant, Oak Ridge, Tennessee (HSW, Inc. 1991).

  7. Towards A Dynamic Object-Oriented Design Metric Plug-in Framework

    Directory of Open Access Journals (Sweden)

    C. H. Loh

    2008-01-01

    Full Text Available Problem Statement: The evolution of software is made difficult by the need to integrate new features with all previously implemented features in software applications. Approach: present study introduced a general-purpose, platform-independent object-oriented design metric plug-in framework called jmetric intended to help building scalable, extendable object-oriented design metric plug-ins. jmetric seeks to address problem by providing the plug-in developer a structured way to separately develop and incrementally integrate independent object-oriented design metrics as plug-ins to a domain specific object-oriented design metrics framework. jmetric was engineered to provide functional building blocks to accelerate the adding, removing and updating of object-oriented design metric plug-ins in tools such as Eclipse, JDeveloper, NetBeans, JBuilder and other Java-based tools. Dependency injection is heavily used in jmetric to accelerate the adding, removing and updating of object-oriented metrics plug-ins. We studied several commonly used integrated development environments and software metrics tools to identify the extendibility of the tools to provide additional object-oriented design metric functionalities as plug-ins. Results: We demonstrate a tool called jmetric tool that had developed as a reference implementation to validate the plug-in capabilities of jmetric. Conclusion: Extending other tools such as Eclipse, JDeveloper and NetBeans to include metric functionalities is possible by wiring plug-ins through dependency injection mechanism in jmetric.

  8. Borehole plugging of man-made accesses to a basalt repository: a preliminary study

    International Nuclear Information System (INIS)

    This report describes the status of work currently in progress for the Basalt Borehole Plugging Program (BBPP). The primary objectives of the BBPP outlined in this report have been met during this first phase of work. These objectives included: (1) the preparation of a preliminary list of candidate plug materials; (2) a description of available machinery capable of placing candidate plug materials; and (3) the development of physical and geochemical testing programs to help evaluate the chemical stability and physical properties of candidate plug materials. The most significant finding from work to date is that given reasonable regulatory criteria, nothing has been identified which would prevent design of a plug system to seal manmade openings leading to a nuclear waste repository in Columbia River basalt for significantly long periods of time (on the order of thousands of years). Work accomplished to date indicates that this plug system can be designed using both natural and manufactured materials and can be emplaced with existing placement machinery and modifications of that machinery. The objectives of Task II are to conduct laboratory tests to evaluate the suitability of preferred candidate materials for plugging boreholes in the proposed repository, select plug system(s), initiate preconceptual machinery design for the placement of materials in plug system(s), and prepare a preliminary Task II report. As with Task I project organization, Task II is divided into subtasks that are identified by written subtask work summaries

  9. Transport of Wetting and Nonwetting Liquid Plugs in a T-shaped Microchannel

    Institute of Scientific and Technical Information of China (English)

    YONG Yumei; LI Sha; YANG Chao; YIN Xiaolong

    2013-01-01

    The transport of liquid plugs in microchannels is very important for many applications such as in medical treatments in airways and in extraction of oil from porous rocks.A plug of wetting and non-wetting liquids driven by a constant pressure difference through a T-shaped microchannel is studied numerically with lattice Boltzmann (LB) method.A two-phase flow LB model based on field mediators is built.Three typical flow patterns (blocking,rupture and splitting flow) of plug flow are obtained with different driving pressures.It is found that it becomes difficult for a plug with short initial plug length to leave the microchannel; the flow pattern of plug transport varies with the contact angle,especially from wetting to nonwetting; with the increase of interracial tension,the front interface of plug moves faster; the front and rear interfaces of the plug with small viscosity ratio move faster in the microchannel than those of the plug with large viscosity ratio.The study is helpful to provide theoretical data for the design and scale-up of liquid-liquid reactors and separators.

  10. Randomized clinical trial comparing percutaneous closure of patent foramen ovale (PFO using the Amplatzer PFO Occluder with medical treatment in patients with cryptogenic embolism (PC-Trial: rationale and design

    Directory of Open Access Journals (Sweden)

    Schuler Gerhard

    2011-02-01

    Full Text Available Abstract Background Several studies have shown an association of cryptogenic stroke and embolism with patent foramen ovale (PFO, but the question how to prevent further events in such patients is unresolved. Options include antithrombotic treatment with warfarin or antiplatelet agents or surgical or endovascular closure of the PFO. The PC-Trial was set up to compare endovascular closure and best medical treatment for prevention of recurrent events. Methods The PC-Trial is a randomized clinical trial comparing the efficacy of percutaneous closure of the PFO using the Amplatzer PFO occluder with best medical treatment in patients with cryptogenic embolism, i.e. mostly cryptogenic stroke. Warfarin for 6 months followed by antiplatelet agents is recommended as medical treatment. Randomization is stratified according to patients age ( Discussion patients were randomized in 29 centers of Europe, Canada, and Australia. Randomization started February 2000. Enrollment of 414 patients was completed in February 2009. All patients will be followed-up longitudinally. Follow-up is maintained until the last enrolled patient is beyond 2.5 years of follow-up (expected in 2011. Trial Registration Trial listed in ClinicalTrials.gov as NCT00166257 and sponsored by AGA Medical, Plymouth, MN, USA

  11. Selecting Female Mice in Estrus and Checking Plugs.

    Science.gov (United States)

    Behringer, Richard; Gertsenstein, Marina; Nagy, Kristina Vintersten; Nagy, Andras

    2016-01-01

    The female mouse estrous cycle is divided into four phases: proestrus (development of ovarian follicles), estrus (ovulation), metestrus (formation of corpora lutea), and diestrus (beginning of follicle development for next ovulation and elimination of previous oocytes). The appearance of the epithelium of the external genitalia is used to identify the stage of the estrous cycle of a female mouse. This is usually easier to see in strains with either no or only light skin pigmentation. By examining the color, moistness, and degree of swelling of the vagina, females in estrus can readily be identified. To set up the matings, females are examined in the afternoon, and those in estrus are placed into the cages with males (one or two females in each cage with one male). Usually, 50% or more of the selected females will mate. The presence of a vaginal copulation plug next morning indicates that mating has occurred, but it does not mean that a pregnancy will result even if proven breeder fertile males were used. It is important to check vaginal plugs early in the morning because they fall out or are no longer detectable ~12 h after mating or sometimes earlier. PMID:27480722

  12. Canadian sponsored plug-in hybrids and their impact

    Energy Technology Data Exchange (ETDEWEB)

    Fitzpatrick, N. [Azure Dynamics Corp., Toronto, ON (Canada)

    2007-07-01

    This paper provided details of plug-in hybrid vehicles designed by Canadian companies and sponsored by the Canadian government. Canada's role in developing PHEVs and its contributions to PHEV research were also explored. The first plug-in hybrid electric vehicle (PHEV) project in Canada involved the design of a parallel hybrid with a 10 kWh battery built by a team at the University of Toronto. After an international symposium on electric vehicles was held in Toronto in 1988, a review of battery activities was conducted across Canada. Results of the review showed that new developments in advanced lithium batteries and magnets would provide new impetus for electric and hybrid vehicle designs. The success of the programs has meant that conventional hybrid technology is now successfully penetrating the delivery vehicle and shuttle bus markets. Canada now holds a leading place in the commercial hybrid vehicle niche. It was concluded that the Canadian government should continue to support programs investigating both drivelines and batteries for hybrid vehicles. 4 refs., 1 tab., 1 fig.

  13. Development and application of microbial selective plugging processes

    Energy Technology Data Exchange (ETDEWEB)

    Jenneman, G.E. [Phillips Petroleum Co., Bartlesville, OK (United States); Gevertz, D.; Davey, M.E. [Agouron Institute, La Jolla, CA (United States)] [and others

    1995-12-31

    Phillips Petroleum Company recently completed a microbial selective plugging (MSP) pilot at the North Burbank Unit (NBU), Shidler, Oklahoma. Nutrients were selected for the pilot that could stimulate indigenous microflora in the reservoir brine to grow and produce exopolymer. It was found that soluble corn starch polymers (e.g., maltodextrins) stimulated the indigenous bacteria to produce exopolymer, whereas simple sugars (e.g., glucose and sucrose), as well as complex media (e.g., molasses and Nutrient Broth), did not. Injection of maltodextrin into rock cores in the presence of indigenous NBU bacteria resulted in stable permeability reductions (> 90%) across the entire length, while injection of glucose resulted only in face plugging. In addition, it was found that organic phosphate esters (OPE) served as a preferable source of phosphorus for the indigenous bacteria, since orthophosphates and condensed phosphates precipitated in NBU brine at reservoir temperature (45{degrees}C). Injection of maltodextrin and ethyl acid phosphate into a producing well stimulated an increase in maltodextrin utilizing bacteria (MUB) in the back-flowed, produced fluid. Additional screens of indigenous and nonindigenous bacteria yielded several nonindigenous isolates that could synthesize polymer when growing in brine containing 6% NaCl at 45{degrees}C.

  14. The sealing performance of bentonite/crushed basalt borehole plugs

    International Nuclear Information System (INIS)

    Mixtures of crushed rock and bentonite are considered for backfilling and sealing high-level nuclear waste repositories. Many variables affect the hydraulic conductivity of such mixtures, including the size and shape of the rock particles, method of mixing and emplacement, water content and density of the clay, and the weight ratio of rock to clay. Mixtures of crushed basalt and bentonite have been tested in two types of permeameters, 20 cm diameter stainless steel permeameters and 10 cm diameter PVC permeameters. Plugs were installed as a single lift or in many lifts; the water content of the clay ranged from air-dry to as high as 200%. Preliminary results show that a mixture of 75% crushed basalt and 25% bentonite has a hydraulic conductivity between 1 x 10-9 cm/s and 2.5 x 10-8 cm/s. In some cases, preferential flow paths have developed (possibly as a result of the montmorillonite washing out of the crushed rock matrix), giving hydraulic conductivities as high as 1 x 10-4 cm/s. Other ratios of rock to clay have similar bimodal results. The probability of failure is decreased by including a higher percentage of clay in the plug, crushing the rock finer, and evenly mixing the crushed rock and clay. 136 refs., 50 figs., 7 tabs

  15. Computational modeling of unsteady surfactant-laden liquid plug propagation in neonatal airways

    Science.gov (United States)

    Olgac, Ufuk; Muradoglu, Metin

    2013-07-01

    Surfactant-free and surfactant-laden liquid plug propagation in neonatal airways in various generations representing the upper and lower airways are investigated computationally using a finite-difference/front-tracking method. Emphasis is placed on the unsteady surfactant-laden plug propagation as a model for Surfactant Replacement Therapy (SRT) and airway reopening. The numerical method is designed to solve the evolution equations of the interfacial and bulk surfactant concentrations coupled with the incompressible Navier-Stokes equations. Available experimental data for surfactant Survanta are used to relate surface tension coefficient to surfactant concentration at the interface. It is found that, for the surfactant-free case, the trailing film thickness is in good agreement with Taylor's law for plugs with plug length greater than the airway width. Mechanical stresses that could be injurious to epithelial cells such as pressure and shear stress and their gradients are maximized on the front and rear menisci with increasing magnitudes in the lower generations. These mechanical stresses, especially pressure and pressure gradient, are diminished with the introduction of surfactants. Surfactant is absorbed onto the trailing film and thickens it, eventually leading to either plug rupture or, if totally consumed prior to rupture, to steadily propagating plug. In the upper airways, initially small plugs rupture rapidly and plugs with comparable initial plug length with the airway width persist and propagate steadily. For a more effective SRT treatment, we recommend utilization of plugs with initial plug length greater than the airway width. Increasing surfactant strength or increasing the initially instilled surfactant concentration is found to be ineffective.

  16. Rock mass sealing: experimental assessment of borehole plug performance. Annual report, June 1983-May 1984

    International Nuclear Information System (INIS)

    This report describes experimental field and laboratory borehole plugging performance assessment studies that have been performed, completed, started, or planned during the period June 1, 1983-May 31, 1984. Results are given from field flow tests on three cement plugs installed in vertical boreholes in basalt and on one nearly horizontal cement plug. The horizontal plus seals the borehole very well, as does one of the vertical plugs. The initial hydraulic conductivity of the other two vertical field plugs has been relatively high, and remedial action is described. Laboratory simulations have been performed to study the influence of dynamic loading on cement plug performance, and no detrimental effects have been detected. Conversely, drying of cement plugs, especially over extended periods of time and at elevated temperatures does increase the hydraulic conductivity of the plugs severely, as well as reducing their bond strength along the plug-rock interface. Microscopic inspection, strength and flow tests on boreholes in basalt have been used to identify the characteristics of a drilling-induced damaged zone in basalt. While such a damaged zone exists, and has typical features (e.g., fracture density, size, location, orientation) determined by the drilling method and the rock characteristics, it is thin and not likely to be a preferential flowpath. A comprehensive suite of standard engineering characterization tests has been performed on seven commercial bentonites, complemented by flow tests on bentonite plugs, chemical analysis and swelling tests. Experimental designs are given for the study of size and of thermal effects on plug performance, and a few preliminary results are presented. Results are included from ongoing cement push-out tests and swelling measurements

  17. Retina vascular network recognition

    Science.gov (United States)

    Tascini, Guido; Passerini, Giorgio; Puliti, Paolo; Zingaretti, Primo

    1993-09-01

    The analysis of morphological and structural modifications of the retina vascular network is an interesting investigation method in the study of diabetes and hypertension. Normally this analysis is carried out by qualitative evaluations, according to standardized criteria, though medical research attaches great importance to quantitative analysis of vessel color, shape and dimensions. The paper describes a system which automatically segments and recognizes the ocular fundus circulation and micro circulation network, and extracts a set of features related to morphometric aspects of vessels. For this class of images the classical segmentation methods seem weak. We propose a computer vision system in which segmentation and recognition phases are strictly connected. The system is hierarchically organized in four modules. Firstly the Image Enhancement Module (IEM) operates a set of custom image enhancements to remove blur and to prepare data for subsequent segmentation and recognition processes. Secondly the Papilla Border Analysis Module (PBAM) automatically recognizes number, position and local diameter of blood vessels departing from optical papilla. Then the Vessel Tracking Module (VTM) analyses vessels comparing the results of body and edge tracking and detects branches and crossings. Finally the Feature Extraction Module evaluates PBAM and VTM output data and extracts some numerical indexes. Used algorithms appear to be robust and have been successfully tested on various ocular fundus images.

  18. Abdominopelvic vascular injuries.

    Science.gov (United States)

    Sriussadaporn, S

    2000-01-01

    The clinical records of 25 patients with 32 abdominopelvic vascular injuries were reviewed. Sixty per cent of patients sustained blunt trauma and 40 per cent sustained penetrating trauma. Nineteen patients (76%) were in shock on arrival, 2 of them underwent ER thoracotomy when they first arrived in the emergency room. Nine patients (36%) had signs of lower extremity ischemia. The Injury Severity Score (ISS) ranged from 16-50, mean 29 +/- 10.0. Nineteen patients (76%) had 35 associated injuries. Of the 32 injured vessels; 8 were external iliac artery, 5 were renal vein, 4 were abdominal aorta, 3 were common iliac artery, common iliac vein, external iliac vein and inferior vena cava, and 1 was superior mesenteric artery, superior mesenteric vein and median sacral artery. Treatments included: 13 lateral repair, 4 prosthetic grafting, 4 nephrectomy, 3 ligation, 3 reversed saphenous vein grafting, 2 end to end anastomosis, 1 internal iliac artery grafting, 1 intravascular shunt and packing and 1 perihepatic packing. Nine patients (36%) died. High mortality was observed in injuries to the abdominal aorta (75%), inferior vena cava (66.7%), common iliac vein (66.7%) and associated major pelvic fractures (50%). Factors significantly associated with mortality were the presence of shock on arrival, associated injuries and high Injury Severity Score. The author concludes that short prehospital time, effective resuscitation and proper surgical decision making are important for survival in these critically injured patients. PMID:10710864

  19. Analysis and methodology for measuring oxygen concentration in liquid sodium with a plugging meter

    International Nuclear Information System (INIS)

    Oxygen concentration in liquid sodium is a critical measurement in assessing the potential for corrosion damage in sodium-cooled fast reactors (SFRs). There has been little recent work on sodium reactors and oxygen detection. Thus, the technical expertise dealing with oxygen measurements within sodium is no longer readily available in the U.S. Two methods of oxygen detection that have been investigated are the plugging meter and the galvanic cell. One of the overall goals of the Univ. of Wisconsin's sodium research program is to develop an affordable, reliable galvanic cell oxygen sensor. Accordingly, attention must first be dedicated to a well-known standard known as a plugging meter. Therefore, a sodium loop has been constructed on campus in effort to develop the plugging meter technique and gain experience working with liquid metal. The loop contains both a galvanic cell test section and a plugging meter test section. Consistent plugging results have been achieved below 20 [wppm], and a detailed process for achieving effective plugging has been developed. This paper will focus both on an accurate methodology to obtain oxygen concentrations from a plugging meter, and on how to easily control the oxygen concentration of sodium in a test loop. Details of the design, materials, manufacturing, and operation will be presented. Data interpretation will also be discussed, since a modern discussion of plugging data interpretation does not currently exist. (authors)

  20. Axial strength of cement borehole plugs in granite and basalt. Topical report on rock mass sealing

    International Nuclear Information System (INIS)

    This report describes experimental and theoretical studies of the axial strength of cement plugs installed in boreholes drilled coaxially in granite and in basalt cylinders. Experimental work has consisted of loading the cement plugs to failure while measuring loads and displacements. Such tests have been performed on borehole plugs with a diameter and a length ranging from 2.5 cm to 10 cm. Results from over one hundred experiments show that the strength is high, sufficient for anticipated loads at repository depths, but very variable, complicating the design of very short plugs. Significant residual strength (thirty to fifty percent of the peak strength) is observed. A frictional model of the interface shear strength, tau = c + sigma(tan phi), in combination with the assumption of an exponential shear stress distribution or plug-rock load transfer, provides the simplest realistic model for plug strength characterization. The integrated strength thus calculated compares moderately well with experimental results. An extensive review is given of more sophisticated analysis procedures that should be of value for general plug design applications. Generic analyses and their implications for plug performance are included. Variability of experimental results complicates the assessment of their direct detailed applicability. 115 references, 70 figures, 19 tables

  1. The remote handling compatibility analysis of the ITER generic upper port plug structure

    NARCIS (Netherlands)

    Ronden, D. M. S.; Dammann, A.; Elzendoorn, B.; Giacomin, T.; Heemskerk, C.; Loesser, D.; Maquet, P.; van Oosterhout, J.; Pak, S.; Pitcher, C. S.; M. Portalès,; Proust, M.; Udintsev, V.S.; Walsh, M. J.

    2014-01-01

    The ITER diagnostics generic upper port plug (GUPP) is developed as a standardized design for all diagnostic upper port plugs, in which a variety of payloads can be mounted. Here, the remote handling compatibility analysis (RHCA) of the GUPP design is presented that was performed for the GUPP final

  2. Plug and Play Process Control Applied to a District Heating System

    DEFF Research Database (Denmark)

    Knudsen, Torben; Trangbæk, Klaus; Kallesøe, Carsten Skovmose

    2008-01-01

    The general ideas within plug and play process control (PTC) are to initialize and reconfigure control systems just by plug and play. In this paper these ideas are applied to a district heating pressure control problem. First of all this serves as a concrete example of PTC, secondly some of the f...

  3. Chinese Standards on Refractories Purging Plugs and Well Blocks for Refining Ladle

    Institute of Scientific and Technical Information of China (English)

    Zhang Xiaohui

    2009-01-01

    @@ 1 Scope This standard specifies the classification,technical requirements,test methods,inspection rules,marking,packing,transportation,storage and quality certificate of purging plugs and well blocks for refining ladle. This standard is applicable to the directional slit purging plugs and well blocks for refining ladle.

  4. Laparoscopically assisted liver biopsy with a hemostatic plug

    NARCIS (Netherlands)

    Karpelowsky, J. S.; Numanoglu, A.; Bax, N. M. A.; Rode, H.

    2006-01-01

    Background: Percutaneous and open liver biopsies are routine procedures for diagnosing liver pathology. However, the procedure can carry significant morbidity and even mortality, especially in the event of an un-correctable coagulopathy or a highly vascular tumor. Methods: A technique described for

  5. Feasibility study of a concrete plug made of low pH concrete

    International Nuclear Information System (INIS)

    In this report a concrete plug, used as a barrier between the deposition tunnels and the access tunnel, is investigated. The objectives of the work is to see whether it is possible to use low pH concrete for the plug and whether it can be designed without using reinforcement. The requirements set on the plug are that the water leakage through it should be small enough and that the concrete stresses are limited to a value valid for the concrete used. A modified geometry of the plug is proposed, which makes it possible to use it as a general solution in all deposition tunnels. Material properties of a low pH concrete (B200) determined by CBI have been used. Loads considered in the study is the pressure from water and swelling, the temperature change in the rock and plug due to heat development from nuclear fuel stored in nearby copper canisters, pre-stressing in the plug due to cooling during construction and the shrinkage of concrete in the plug. Two-dimensional, axis-symmetric finite element analyses, assuming linear elastic material behaviour in rock and concrete where contact friction between concrete and rock is taken into consideration, have been used to study the structural response of the plug. A total of 48 main load combinations, consisting of 8 different load scenarios and 6 material combinations, have been used. It is found that the concrete plug will not remain uncracked when subjected to the loads studied but that it, nevertheless, is possible to achieve an unreinforced concrete plug that satisfies the requirements set up. The minimum size of the concrete compressed zone will be 0.5 m, resulting in a water leakage through the plug determined to be lower than the requirement of 0.01 l/min set up in this study. Further, the maximum compressive stresses of interest are 33 MPa and the maximum displacement in the plug is about 3 mm, which are deemed to be satisfactorily. Consequently, it is concluded that it seems possible to use low pH concrete for the plug

  6. Ultrasound in vascular disease & introduction

    OpenAIRE

    Deane, C; S.Castellani; B. Brkljacic

    2012-01-01

    Il capitolo descrive i prin cipi generali fondamentali delle tecniche per la valutazione ultrasonografica con doppler vascolare The chapter describes the fundamental principles underlying the use of ultrasonographic techniques of vascular doppler

  7. Diabetes and Retinal Vascular Dysfunction

    Directory of Open Access Journals (Sweden)

    Eui Seok Shin

    2014-01-01

    Full Text Available Diabetes predominantly affects the microvascular circulation of the retina resulting in a range of structural changes unique to this tissue. These changes ultimately lead to altered permeability, hyperproliferation of endothelial cells and edema, and abnormal vascularization of the retina with resulting loss of vision. Enhanced production of inflammatory mediators and oxidative stress are primary insults with significant contribution to the pathogenesis of diabetic retinopathy (DR. We have determined the identity of the retinal vascular cells affected by hyperglycemia, and have delineated the cell autonomous impact of high glucose on function of these cells. We discuss some of the high glucose specific changes in retinal vascular cells and their contribution to retinal vascular dysfunction. This knowledge provides novel insight into the molecular and cellular defects contributing to the development and progression of diabetic retinopathy, and will aid in the development of innovative, as well as target specific therapeutic approaches for prevention and treatment of DR.

  8. Self locking drive system for rotating plug of a nuclear reactor

    International Nuclear Information System (INIS)

    A self locking drive system for rotating the plugs on the head of a nuclear reactor which is able to restrain plug motion if a seismic event whould occur during reactor refueling is described. A servomotor is engaged via a gear train and a bull gear to the plug. Connected to the gear train is a feedback control system which allows the motor to rotate the plug to predetermined locations for refueling of the reactor. The gear train contains a self locking double enveloping worm gear set. The worm gear set is utilized for its self locking nature to prevent unwanted rotation of the plugs as the result of an earthquake. The double enveloping type is used because its unique contour spreads the load across several teeth providing added strength and allowing the use of a conventional size worm

  9. Final report of the borehole, shaft, and tunnel sealing test - Volume 1: Borehole plugging

    International Nuclear Information System (INIS)

    The Borehole Plugging Experiment comprised field tests of the sealing function and the practicality in handling and application of plugs consisting of segments of perforated metal casings filled with cylindrical blocks of highly compacted sodium bentonite. Preparative tests had shown that the clay swells out through the perforation and embeds the casings. The field tests demonstrated that even very long holes can be effectively sealed by such plugs and that the clay becomes very homogeneous and forms a tight contact with the rock in a relatively short time. By that the plugs become practically impervious and the flow along the clay/rock contact will be insignificant. The longevity of such plugs extends over several thousands years under the conditions that usually prevail in crystalline rock. (author) 8 refs., 37 figs., 8 tabs

  10. Small Intestinal Submucosa Plug for Closure of Dilated Nephrostomy Tracts: A Pilot Study in Swine

    International Nuclear Information System (INIS)

    The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.

  11. Vascular graft infections with Mycoplasma

    DEFF Research Database (Denmark)

    Levi-Mazloum, Niels Donald; Skov Jensen, J; Prag, J;

    1995-01-01

    laboratory techniques, the percentage of culture-negative yet grossly infected vascular grafts seems to be increasing and is not adequately explained by the prior use of antibiotics. We have recently reported the first case of aortic graft infection with Mycoplasma. We therefore suggest the hypothesis that...... the large number of culture-negative yet grossly infected vascular grafts may be due to Mycoplasma infection not detected with conventional laboratory technique....

  12. The relationships of vascular plants.

    OpenAIRE

    Kenrick, P

    2000-01-01

    Recent phylogenetic research indicates that vascular plants evolved from bryophyte-like ancestors and that this involved extensive modifications to the life cycle. These conclusions are supported by a range of systematic data, including gene sequences, as well as evidence from comparative morphology and the fossil record. Within vascular plants, there is compelling evidence for two major clades, which have been termed lycophytes (clubmosses) and euphyllophytes (seed plants, ferns, horsetails)...

  13. The pathobiology of vascular dementia

    OpenAIRE

    Iadecola, Costantino

    2013-01-01

    Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to full-blown dementia, attributable to cerebrovascular causes. Often coexisting with Alzheimer’s disease, mixed vascular and neurodegenerative dementia has emerged as the leading cause of age-related cognitive impairment. Central to the disease mechanism is the crucial role that cerebral blood vessels play in brain health, not only for the delivery of oxygen and nutrients, but also for the trophic si...

  14. Plug-in hybrid electric vehicles in smart grid

    Science.gov (United States)

    Yao, Yin

    In this thesis, in order to investigate the impact of charging load from plug-in hybrid electric vehicles (PHEVs), a stochastic model is developed in Matlab. In this model, two main types of PHEVs are defined: public transportation vehicles and private vehicles. Different charging time schedule, charging speed and battery capacity are considered for each type of vehicles. The simulation results reveal that there will be two load peaks (at noon and in evening) when the penetration level of PHEVs increases continuously to 30% in 2030. Therefore, optimization tool is utilized to shift load peaks. This optimization process is based on real time pricing and wind power output data. With the help of smart grid, power allocated to each vehicle could be controlled. As a result, this optimization could fulfill the goal of shifting load peaks to valley areas where real time price is low or wind output is high.

  15. Control of resistance plug welding using quantitative feedback theory

    Energy Technology Data Exchange (ETDEWEB)

    Bentley, A.E. [Sandia National Lab., Albuquerque, NM (United States); Horowitz, I. [Univ. of California, Davis, CA (United States)]|[Weizmann Inst. of Science, Rehovot (Israel)]|[Wright Patterson Air Force Base, Dayton, OH (United States); Chait, Y.; Rodrigues, J. [Univ. of Massachusetts, Amherst, MA (United States)

    1996-12-01

    Resistance welding is used extensively throughout the manufacturing industry. Variations in weld quality often result in costly post-weld inspections. Applications of feed-back control to such processes have been limited by the lack of accurate models describing the nonlinear dynamics of this process. A new system based on electrode displacement feedback is developed that greatly improves quality control of the resistance plug welding process. The system is capable of producing repeatable welds of consistent displacement (and thus consistent quality), with wide variations in weld parameters. This paper describes the feedback design of a robust controller using Quantitative Feedback Theory for this highly complex process, and the experimental results of the applied system.

  16. Battery Test Manual For Plug-In Hybrid Electric Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey R. Belt

    2010-09-01

    This battery test procedure manual was prepared for the United States Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), Vehicle Technologies Program. It is based on technical targets established for energy storage development projects aimed at meeting system level DOE goals for Plug-in Hybrid Electric Vehicles (PHEV). The specific procedures defined in this manual support the performance and life characterization of advanced battery devices under development for PHEV’s. However, it does share some methods described in the previously published battery test manual for power-assist hybrid electric vehicles. Due to the complexity of some of the procedures and supporting analysis, a revision including some modifications and clarifications of these procedures is expected. As in previous battery and capacitor test manuals, this version of the manual defines testing methods for full-size battery systems, along with provisions for scaling these tests for modules, cells or other subscale level devices.

  17. Battery Test Manual For Plug-In Hybrid Electric Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey R. Belt

    2010-12-01

    This battery test procedure manual was prepared for the United States Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), Vehicle Technologies Program. It is based on technical targets established for energy storage development projects aimed at meeting system level DOE goals for Plug-in Hybrid Electric Vehicles (PHEV). The specific procedures defined in this manual support the performance and life characterization of advanced battery devices under development for PHEV’s. However, it does share some methods described in the previously published battery test manual for power-assist hybrid electric vehicles. Due to the complexity of some of the procedures and supporting analysis, a revision including some modifications and clarifications of these procedures is expected. As in previous battery and capacitor test manuals, this version of the manual defines testing methods for full-size battery systems, along with provisions for scaling these tests for modules, cells or other subscale level devices.

  18. Wireless Plug and Play Control Systems: Hardware, Networks, and Protocols

    DEFF Research Database (Denmark)

    Meybodi, Soroush Afkhami

    2012-01-01

    protocols that can fulfill the stringent requirements of P3C case studies in general. In this part, after a thorough review of available Access and Routing protocols in industrial wireless networks, a combination of a deterministic Medium Access Control (MAC) protocol and a clustered flooding-based routing...... accordance with the control topology. Functionality of the new routing metric is verified by simulations within a flooding-based routing algorithm. The results of this research project create a clear and concise interface for the other work packages of P3C which are concluded earlier.......This dissertation reports the result of efforts to identify and solve the problems that arise when a control system is to be designed for various industrial case studies of the Plug and Play Process Control (P3C) project that require autonomous addition/removal of sensors, actuators and subsystems...

  19. Calcium dynamics in vascular smooth muscle

    OpenAIRE

    Amberg, Gregory C.; Navedo, Manuel F.

    2013-01-01

    Smooth muscle cells are ultimately responsible for determining vascular luminal diameter and blood flow. Dynamic changes in intracellular calcium are a critical mechanism regulating vascular smooth muscle contractility. Processes influencing intracellular calcium are therefore important regulators of vascular function with physiological and pathophysiological consequences. In this review we discuss the major dynamic calcium signals identified and characterized in vascular smooth muscle cells....

  20. Mechanistic Understanding of Microbial Plugging for Improved Sweep Efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Steven Bryant; Larry Britton

    2008-09-30

    Microbial plugging has been proposed as an effective low cost method of permeability reduction. Yet there is a dearth of information on the fundamental processes of microbial growth in porous media, and there are no suitable data to model the process of microbial plugging as it relates to sweep efficiency. To optimize the field implementation, better mechanistic and volumetric understanding of biofilm growth within a porous medium is needed. In particular, the engineering design hinges upon a quantitative relationship between amount of nutrient consumption, amount of growth, and degree of permeability reduction. In this project experiments were conducted to obtain new data to elucidate this relationship. Experiments in heterogeneous (layered) beadpacks showed that microbes could grow preferentially in the high permeability layer. Ultimately this caused flow to be equally divided between high and low permeability layers, precisely the behavior needed for MEOR. Remarkably, classical models of microbial nutrient uptake in batch experiments do not explain the nutrient consumption by the same microbes in flow experiments. We propose a simple extension of classical kinetics to account for the self-limiting consumption of nutrient observed in our experiments, and we outline a modeling approach based on architecture and behavior of biofilms. Such a model would account for the changing trend of nutrient consumption by bacteria with the increasing biomass and the onset of biofilm formation. However no existing model can explain the microbial preference for growth in high permeability regions, nor is there any obvious extension of the model for this observation. An attractive conjecture is that quorum sensing is involved in the heterogeneous bead packs.

  1. A study on the thermal shock for explosive plugged part

    International Nuclear Information System (INIS)

    Supposing the thermal shock which take place in the heat-exchanger due to misoperation of valves, thermal shock test of explosive plugged part is conducted under severer condition than that in service. Microscopic inspection (x 200) of the section of specimen after thermal shock test, ultrasonic inspection and observation of acoustic emission during testing are conducted to detect the peeling of bonded boundary and cracking in the material. SUS 321 steel, 2 1/4 Cr - 1 Mo steel and SUS 304 steel are used as testing materials, supposing the material of the super heater, and evaporator of FBR, and steam generater of PWR, respectively. Range of temperature variation are also desided supposing the operating temperature of secondary cooling circuit of each type of reactor. Reasults of testing are plotted against the number of heating and cooling cycles. However, peeling is seemed to take place in short period after beginning of the testing, considerable number of cycles are required to initiate the cracks and to propagate them to inside of plug or outside surface of tube plate. Mechanism of fracture due to thermal shock are considered and it is concluded that there are three type of fracture depending on the result of welding. Conclusions of these investigations are obtained as follows. 1. Failures of explosive welded part are divided into two types, peeling and cracking. 2. There are three type of crack initiation, i.e. crack initiation from peeling, crack initiation from unbonded zone near the surface of tube plate, and crack initiation from melting zone in bonded boundary. 3. It is possible to distinguish the peeling and cracking by AE, however, it is impossible to distinguish the above three type of crack initiation by AE. 4. Peeling occurs immediately after beginning of test but cracking occurs after 150 ∼ 200 cycles in SH, 200 ∼ 400 cycles in EV and 1000 cycles in SG. (J.P.N.)

  2. An illustrative 'plug & play' catastrophe model for groundwater flooding

    Science.gov (United States)

    Wang, Lei; Hillier, John; Royse, Kate; Lee, Tzu-Fung; O'Niel, Jullian; Kingdon, Andrew; Hughes, Andrew

    2013-04-01

    Economic losses from natural catastrophes are substantial; e.g., US130 billion in 2010. 'Catastrophe models' are stochastic event-set based models that simulate these risks and underpin their assessment in the insurance industry. Most catastrophe models are proprietary 'black boxes', which limit the level of user interaction, but new regulations (Solvency II) require firms to understand better the assumptions upon which the calculations ultimately rest. Part of this greater transparency requires constraining where uncertainty originates, perhaps by interchanging components provided by rival model vendors in 'plug and play' catastrophe models. The objective of this paper is to demonstrate a practical, accessible way in which this may be made possible. Specifically to do this the first, illustrative 'plug and play' model was created efficiently and effectively using OpenMI, a free 'open-source' model linking standard. In about 100 man-hours climate, groundwater flow, vulnerability, exposure and loss components were linked to output financial losses, i.e., occurrence exceedance probability (OEP) curves. Groundwater flooding near Marlborough (UK) is used for this proof of concept. Losses from this example dataset are small, about £3.8 million for a 33 yr OEP, but groundwater is an important compounding factor in UK flooding and this is the first, albeit rudimentary, attempt to probabilistically model loss for this hazard. Selected components are swopped, and losses calculated to show how insights into the origin of uncertainty can be gained. Crucially, OpenMI has the future potential to operate online and shield valuable data within components whilst allowing them to be swopped. So, it has the potential to underpin a secure, open-source, practical framework of use to the insurance industry.

  3. Hydrotransport plugging study. FY 1980-1981 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Eyler, L.L.; Lombardo, NJ.; Barnhart, J.S.

    1982-09-01

    Large-particle hydrotransport flow phenomena are analyzed. These include particle suspension mechanisms, relative in situ slip between phases, and shear between separated solid/liquid flow regions. These phenomena are related to the mechanistic force balance modeling approach to predicting nominal and minimum horizontal pipeline transport conditions. Results of four series of tests in a 35 m-long, 0.165 m-diameter plexiglass pipeline are presented. These tests were designed to investigate isolated flow phenomena related to lower limits of operation of large-particle transport. They included measurements of the particle size dependence and flow geometry dependence on interfacial friction factors, initiation of plug flow motion, and plugging tendencies of flow through upward-turning elbows. Numerous flow phenomena and parameter dependencies are included in analysis of predictions made using the force balance modeling approach. Comparisons with data are made where possible and a step-by-step solution procedure is presented. Results show agreement with some data sets and disagreement with others. Most available data, however, are neither extensive enough nor accurate enough to form complete conclusions as to the minimum operating conditions predicted with the force balance modeling approach. Additional data from a systematic experimental program in a once-through pipeline system are necessary to further verify the modeling approach. A limited qualitative analysis of methods proposed to unplug large particle pipelines is presented. Methods assessed include pulsed air injection, vibration augmentation, friction reducing surfactant injection, and mechanical or hydraulic boring machinery. Advantages and disadvantages of each method are assessed qualitatively. Laboratory and field testing are required to determine applications.

  4. Plug-and-play modules for flexible radiosynthesis

    International Nuclear Information System (INIS)

    We present a plug-and-play radiosynthesis platform and accompanying computer software based on modular subunits that can easily and flexibly be configured to implement a diverse range of radiosynthesis protocols. Modules were developed that perform: (i) reagent storage and delivery, (ii) evaporations and sealed reactions, and (iii) cartridge-based purifications. The reaction module incorporates a simple robotic mechanism that removes tubing from the vessel and replaces it with a stopper prior to sealed reactions, enabling the system to withstand high pressures and thus provide tremendous flexibility in choice of solvents and temperatures. Any number of modules can rapidly be connected together using only a few fluidic connections to implement a particular synthesis, and the resulting system is controlled in a semi-automated fashion by a single software interface. Radiosyntheses of 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG), 1-[18F]fluoro-4-nitrobenzene ([18F]FNB), and 2′-deoxy-2′-[18F]fluoro-1-β-D-arabinofuranosyl cytosine (D-[18F]FAC) were performed to validate the system and demonstrate its versatility. - Highlights: • A flexible, plug-and-play radiosynthesis platform based on modules was developed. • Reaction, reagent delivery, and purification modules can be readily configured for diverse syntheses. • The reaction module is capable of high-pressure sealed reactions without solvent loss. • Any number of modules can be combined and controlled in a semi-automated fashion using a personal computer. • Syntheses of [18F]FDG, [18F]FNB, and D-[18F]FAC demonstrate versatility

  5. Sexual behavior, cannibalism, and mating plugs as sticky traps in the orb weaver spider Leucauge argyra (Tetragnathidae)

    Science.gov (United States)

    Aisenberg, Anita; Barrantes, Gilbert

    2011-07-01

    Unpublished field observations in Leucauge argyra, a tropical orb weaver spider, suggest the occurrence of conspicuous mating plugs that could reduce or prevent remating attempts. Otherwise, the sexual behavior of this species remains unknown. The aims of this study were to describe the courtship behavior and copulation in L. argyra and investigate mating plug formation in this species. Fourteen virgin females and 12 plugged females were exposed to up to three males and checked for mating plug formation. Of the 12 virgins that copulated, nine produced plugs (five immediately after copulation), and the five plugged females that copulated produced another mating plug immediately after copulation. We did not detect the transfer of any male substance during copulation but observed a whitish liquid emerging from female genital ducts. Plug formation was positively associated with male twanging during courtship. One virgin and four plugged females cannibalized males. In seven trials with virgins and in three trials with plugged females, the male's palp adhered to a substance that emerged from female genital ducts and spread on her genital plate. The male had to struggle energetically to free his glued palp; two of these males were cannibalized while trying to release their palps. Females seem to determine copulation duration by altering the timing of mating plug formation and through sexual cannibalism. This is the first case reported of a mating plug as a sticky trap for males.

  6. Obesity in Indian subjects with Vascular Dementia

    OpenAIRE

    CHANDRA, Mina; Anand, Kuljeet Singh Anand

    2015-01-01

    ABSTRACT Background: Obesity is considered a public health challenge in South Asia. Obesity is an independent risk factor in vascular dementia. It also contributes to other risk factors of vascular dementia like hypertension, coronary artery disease, dyslipidaemia and diabetes. As the rate of obesity in Indian subjects with vascular dementia is not known, we decided to assess obesity in subjects with vascular dementia. Methods: Subjects with vascular dementia presenting to Mem...

  7. Atrial septal defects type II: noninvasive evaluation of patients before implantation of an amplatzer septal occluder and on follow-up by magnetic resonance imaging compared with TEE and invasive measurement

    International Nuclear Information System (INIS)

    The purpose of this study was to evaluate morphological and functional MRI of atrial septal defects (ASD) before and after interventional occlusion by the Amplatzer Septal Occluder (AOC) in comparison to trans-oesophageal echocardiography (TEE), invasive balloon measurement (IVBM) and cardiac catheterisation (QCC). Sixty patients with an ASD type II were enrolled. They underwent TEE, IVBM, QCC and MRI at 1.5T. Cine gradient echo, steady-state free precession sequences and a gradient echo phase contrast sequence were used. In MRI, pulmonary-to-systemic flow ratio (Qp/Qs) was calculated and compared with the QCC Qp/Qs ratio. Qp/Qs ratio in baseline MRI examination was 1.56 ± 0.29 (range: 1.05-2.2) and in QCC 1.71 ± 0.30 (range: 1.2-2.4) with a significant correlation (R = 0.65, P < 0.01). Defect size on MRI was 15.3 ± 7.4 mm (range: 3-30 mm), in TEE 14.3 ± 4.9 mm (range: 4-24 mm), and the balloon stretched diameter in IVBM was 23.4 ± 4.2 mm (range: 14-32 mm). Correlation between defect size in MRI vs. TEE was R = 0.67 (P < 0.01) and MRI vs. IVBM was R = 0.77 (P < 0.01). Right ventricular volumes decreased after intervention. MRI is an accurate noninvasive test for diagnosis, planning and follow-up after interventional ASD occlusion using an AOC. (orig.)

  8. Atrial septal defects type II: noninvasive evaluation of patients before implantation of an amplatzer septal occluder and on follow-up by magnetic resonance imaging compared with TEE and invasive measurement

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Christoph; Adam, Gerhard [University Medical Center Hamburg-Eppendorf, Diagnostic Center, Department of Diagnostic and Interventional Radiology, Hamburg (Germany); Weber, Michael; Ekinci, Okan; Neumann, Thomas; Deetjen, Anja; Rolf, Andreas; Hamm, Christian W.; Dill, Thorsten [Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim (Germany)

    2008-11-15

    The purpose of this study was to evaluate morphological and functional MRI of atrial septal defects (ASD) before and after interventional occlusion by the Amplatzer Septal Occluder (AOC) in comparison to trans-oesophageal echocardiography (TEE), invasive balloon measurement (IVBM) and cardiac catheterisation (QCC). Sixty patients with an ASD type II were enrolled. They underwent TEE, IVBM, QCC and MRI at 1.5T. Cine gradient echo, steady-state free precession sequences and a gradient echo phase contrast sequence were used. In MRI, pulmonary-to-systemic flow ratio (Qp/Qs) was calculated and compared with the QCC Qp/Qs ratio. Qp/Qs ratio in baseline MRI examination was 1.56 {+-} 0.29 (range: 1.05-2.2) and in QCC 1.71 {+-} 0.30 (range: 1.2-2.4) with a significant correlation (R = 0.65, P < 0.01). Defect size on MRI was 15.3 {+-} 7.4 mm (range: 3-30 mm), in TEE 14.3 {+-} 4.9 mm (range: 4-24 mm), and the balloon stretched diameter in IVBM was 23.4 {+-} 4.2 mm (range: 14-32 mm). Correlation between defect size in MRI vs. TEE was R = 0.67 (P < 0.01) and MRI vs. IVBM was R = 0.77 (P < 0.01). Right ventricular volumes decreased after intervention. MRI is an accurate noninvasive test for diagnosis, planning and follow-up after interventional ASD occlusion using an AOC. (orig.)

  9. Low-pH concrete plug for sealing the KBS-3V deposition tunnels

    Energy Technology Data Exchange (ETDEWEB)

    Malm, Richard (Vattenfall Power Consultant AB (Sweden))

    2012-01-15

    In SKB's main alternative for final repository of radioactive material, KBS-3V, the backfilled deposition tunnels will be separated from the remaining tunnel system with concrete plugs. These concrete plugs will be designed for a life span of 100 years and their function shall maintain until the transport tunnels outside the plug are backfilled and the natural geohydrological conditions have been restored. The purpose of this report is to document the results and the evaluation from this project and motivate the choice of the most appropriate design for closing the deposition tunnels in the spent fuel repository. The purpose has also been to investigate and present the loads acting on the plug system and determine the load capacity of the concrete plug. This report is the result of a project conducted between 2009-01-01 - 2010-12-31 and the project group has made its assessment based on the conditions and requirements that are present today. The entire design of the plug system is part of this project, where the plug system consists of a filter, a bentonite seal and a cast-in-place concrete plug. Two different conceptual design alternatives for the concrete plug have been studied in this report, one long tapered plug and one dome shaped plug. The results in this report focus on the choice of the conceptual design for the concrete plug and its possibility to assist the entire plug system to satisfy its requirements. It is a complicated task to dispose the radioactive waste and it sets high technical requirements on the design and the production of the backfill and the closing of the deposition tunnels. The aim of this project is to design and develop a plug system suitable for production. This is done by the means of numerical calculations and analyses. The primary function of the concrete plug is to act as a resistance to the external loads originated from the axial expansion of the backfill and the water pressure. However, the entire plug system has a

  10. Low-pH concrete plug for sealing the KBS-3V deposition tunnels

    International Nuclear Information System (INIS)

    In SKB's main alternative for final repository of radioactive material, KBS-3V, the backfilled deposition tunnels will be separated from the remaining tunnel system with concrete plugs. These concrete plugs will be designed for a life span of 100 years and their function shall maintain until the transport tunnels outside the plug are backfilled and the natural geohydrological conditions have been restored. The purpose of this report is to document the results and the evaluation from this project and motivate the choice of the most appropriate design for closing the deposition tunnels in the spent fuel repository. The purpose has also been to investigate and present the loads acting on the plug system and determine the load capacity of the concrete plug. This report is the result of a project conducted between 2009-01-01 - 2010-12-31 and the project group has made its assessment based on the conditions and requirements that are present today. The entire design of the plug system is part of this project, where the plug system consists of a filter, a bentonite seal and a cast-in-place concrete plug. Two different conceptual design alternatives for the concrete plug have been studied in this report, one long tapered plug and one dome shaped plug. The results in this report focus on the choice of the conceptual design for the concrete plug and its possibility to assist the entire plug system to satisfy its requirements. It is a complicated task to dispose the radioactive waste and it sets high technical requirements on the design and the production of the backfill and the closing of the deposition tunnels. The aim of this project is to design and develop a plug system suitable for production. This is done by the means of numerical calculations and analyses. The primary function of the concrete plug is to act as a resistance to the external loads originated from the axial expansion of the backfill and the water pressure. However, the entire plug system has a requirement

  11. 3D FEM Simulation of Rolling Load Working on Piercer Plug in Mannesmann Piercing Process

    Science.gov (United States)

    Yoshida, Motohisa

    2010-06-01

    This paper presents 3D FEM simulation of piercer plug in Mannesmann piercing process. Target is establishment of a virtual piercing experiment tool to assistant piercer plug development. FEM simulation analysis has been applied to Mannesmann piercing process previously. Aspect of those studies is how to simulate material flow in piercing process, especially focused on how to describe ductile fracture which is known as Mannesmann effect. Thus far, simulation of rolling tools has not been focused. Present piercer plugs, made of special alloys, are damaged severely and quickly in case of piercing higher Cr contented alloys in seamless steel tube production process. Therefore, development of FEM simulation on rolling tools has been demanded in production side. 3D FEM analysis of piercer plug is performed with ALE (Arbitrary Lagrangian—Eulerian) method by using ABAQUS/Explicit 6.9. Simulations are thermo-mechanical, elasto-plastic coupled, and dynamic calculation. Piercer plug and the billet are modeled by solid elements to analyze various factors on stress, strain and temperature. Ductile fracture is not considered in the simulations. Simulation results are correlated sufficiently to experimental results on damage of piercer plugs. Verifying absolute value of simulated factors is hard since there are few empirical methods to measure them. As a conclusion, studied simulations are sufficient as a virtual piercing experiment tool to develop higher performance piercer plugs.

  12. Experimental investigation of liquid-liquid plug formation in a T-junction microchannel

    Science.gov (United States)

    Angeli, Panagiota; Chinaud, Maxime; Roumpea, Eynagelia-Panagiota; Weheliye, Weheliye; Omar. K. Matar Collaboration; Lyes Kahouadji Collaboration

    2015-11-01

    Plug formation mechanism of two immiscible liquids was studied experimentally in a 200 μm microchannel using two innovative micro Particle Image Velocimetry (μ PIV) techniques i.e. two-colour μ PIV and high speed bright field μ PIV. The aqueous phase was a water/glycerol solution whereas the organic phase was silicon oil with a range of viscosities from 5 to 155 cSt. Experiments were conducted for different fluid flow rate combinations in the T-junction inlet and it was observed that velocity profiles within the forming plugs depend on the flow rate ratios. The velocity field studies provided insight into the plug mechanism revealing that the interface curvature at the rear of the forming plug changes sign at the later stages of plug formation and accelerates the thinning of the meniscus leading to plug breakage. Results from the two-colour PIV show that the continuous phase resists the flow of the dispersed phase into the main channel at the rear of the plug meniscus and causes the change in the interface curvature. Department of Chemical Engineering South Kensington Campus Imperial College London SW7 2AZ.

  13. Preconceptual systems and equipment for plugging of man-made accesses to a repository in basalt

    International Nuclear Information System (INIS)

    This report presents results of a study leading to preconceptual designs for plugging boreholes, shafts, and tunnels to a nuclear waste repository in basalt. Beginning design criteria include a list of preferred plug materials and plugging machines that were selected to suit the environmental conditions, and depths, diameters, and orientations of the accesses to a nuclear waste repository in the Columbia River basalts located in eastern Washington State. The environmental conditions are described. The fiscal year 1979-1980 Task II work is presented in two parts: preliminary testing of materials for plugging of man-made accesses to a repository in basalt (described in a separate report); and preconceptual systems and equipment for plugging of man-made accesses to a repository in basalt (described in this report). To fulfill the scope of the Task II work, Woodward-Clyde Consultants (WCC) was requested to: provide preconceptual systems for plugging boreholes, tunnels, and shafts in basalt; describe preconceptual borehole plugging equipment for placing the selected materials in man-made accesses; utilize the quality assurance program, program plan and schedule, and work plans previously developed for Task II; and prepare a preliminary report

  14. Vascular calcification: Inducers and inhibitors

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Donghyun, E-mail: dhlee@cau.ac.kr [Department of Biomedical Engineering, Division of Integrative Engineering, Chung-Ang University, 221 Heukseok-Dong, Dongjak-Gu, Seoul 156-756 (Korea, Republic of)

    2011-09-15

    Highlights: {center_dot} Types of vascular calcification processes. {center_dot} Inducers of vascular calcification. {center_dot} Inhibitors of vascular calcifications. {center_dot} Clinical utility for vascular calcification therapy. {center_dot} Implications for the development of new tissue engineering strategies. - Abstract: Unlike the traditional beliefs, there are mounting evidences suggesting that ectopic mineral depositions, including vascular calcification are mostly active processes, many times resembling that of the bone mineralization. Numbers of agents are involved in the differentiation of certain subpopulation of smooth muscle cells (SMCs) into the osteoblast-like entity, and the activation and initiation of extracellular matrix ossification process. On the other hand, there are factors as well, that prevent such differentiation and ectopic calcium phosphate formation. In normal physiological environments, activities of such procalcific and anticalcific regulatory factors are in harmony, prohibiting abnormal calcification from occurring. However, in certain pathophysiological conditions, such as atherosclerosis, chronic kidney disease (CKD), and diabetes, such balances are altered, resulting in abnormal ectopic mineral deposition. Understanding the factors that regulate the formation and inhibition of ectopic mineral formation would be beneficial in the development of tissue engineering strategies for prevention and/or treatment of such soft-tissue calcification. Current review focuses on the factors that seem to be clinically relevant and/or could be useful in developing future tissue regeneration strategies. Clinical utilities and implications of such factors are also discussed.

  15. An integrated evaluation of the performance effects of steam generator tube plugging

    International Nuclear Information System (INIS)

    The integrity of the walls of a small number of steam generator tubes can degrade, with time, during normal operation of a Pressurized Water Reactor. In order to avoid the potential for unacceptable primary-to-secondary leakage, these steam generator tubes must be plugged. This paper presents an integrated evaluation of the impact of tube plugging on plant performance. Such an evaluation is recommended for determining the number of tubes that can be plugged without a significant adverse impact on plant steady state design performance and a large reduction in plant safety analyses margins

  16. Impact of Plug-In Hybrid Electric Vehicles on the Electricity System

    OpenAIRE

    Clement-Nyns, Kristien

    2010-01-01

    Plug-in hybrid electric vehicles, are rapidly gaining interest. Batteries of plug-in hybrid electric vehicles are charged by either plugging into electric outlets or by an on-board generator. For grid charging, these batteries are supplied by power from the grid at home from a standard outlet or on a corporate car park. The extra electrical load, from charging the batteries, has an impact on the electricity system in general and more specifically on the distribution grid and the electricity g...

  17. The Impact of Charging Plug-In Hybrid Electric Vehicles on a Residential Distribution Grid

    OpenAIRE

    Clement-Nyns, Kristien; Haesen, Edwin; Driesen, Johan

    2010-01-01

    Alternative vehicles, such as plug-in hybrid electric vehicles, are becoming more popular. The batteries of these plug-in hybrid electric vehicles are to be charged at home from a standard outlet or on a corporate car park. These extra electrical loads have an impact on the distribution grid which is analyzed in terms of power losses and voltage deviations. Without coordination of the charging, the vehicles are charged instantaneously when they are plugged in or after a fixed start delay. Thi...

  18. The chemical-in-plug bacterial chemotaxis assay is prone to false positive responses

    Directory of Open Access Journals (Sweden)

    Ward Mandy J

    2010-03-01

    Full Text Available Abstract Background Chemical-in-plug assays are commonly used to study bacterial chemotaxis, sometimes in the absence of stringent controls. Results We report that non-chemotactic and non-motile mutants in two distinct bacterial species (Shewanella oneidensis and Helicobacter pylori show apparent zones of accumulation or clearing around test plugs containing potential attractants or repellents, respectively. Conclusions Our results suggest that the chemical-in-plug assay should be used with caution, that non-motile or non-chemotactic mutants should be employed as controls, and that results should be confirmed with other types of assays.

  19. [An almost fatal airway obstruction caused by a secretion plug in an endotracheal tube].

    Science.gov (United States)

    Andersen, Emir Benjamin; Olsen, Karsten Skovgaard

    2014-12-15

    Airway obstruction caused by a secretion plug in an endotracheal tube or a tracheostomy cannula can be a serious complication to mechanical ventilation. This case describes an event caused by a mucus plug localized to the distal part of a tracheostomy tube in a tetraplegic patient. The plug functioned as a check valve, allowing air to pass in - but not out - of the patient. A suction catheter could be passed through the airway without any resistance, and thus the airway was believed to be free. The event, which had an almost fatal outcome due to hyperinflation of the lungs, was relieved by replacement of the tracheostomy cannula. PMID:25497629

  20. Simulation on friction taper plug welding of AA6063-20Gr metal matrix composite

    Science.gov (United States)

    Hynes, N. Rajesh Jesudoss; Nithin, Abeyram M.

    2016-05-01

    Friction taper plug welding a variant of friction welding is useful in welding of similar and dissimilar materials. It could be used for joining of composites to metals in sophisticated aerospace applications. In the present work numerical simulation of friction taper plug welding process is carried out using finite element based software. Graphite reinforced AA6063 is modelled using the software ANSYS 15.0 and temperature distribution is predicted. Effect of friction time on temperature distribution is numerically investigated. When the friction time is increased to 30 seconds, the tapered part of plug gets detached and fills the hole in the AA6063 plate perfectly.

  1. Plugging the biopsy tract in rabbit liver : gelfoam, fibrin sealant and NBCA

    International Nuclear Information System (INIS)

    To evaluate the effect of plugging the biopsy tract in rabbit liver and the pathologic changes caused by plugging materials. Thirty-two New Zealand White rabbits were divided into four groups (eight rabbits in each) and compared with one another. They were labeled group A (control), B (gelfoam), C (fibrin sealant) or D (NBCA). the liver was exposed and biopsied with an 18G disposable biopsy gun. The inner Tru-cut needle was withdrawn and plugging was undertaken through the outer cannula of the biopsy gun. Bleeding times of each material were compared. The rabbits were sacrificed and pathologically evaluated for 17 days

  2. Small-Scale Spray Releases: Orifice Plugging Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Mahoney, Lenna A.; Gauglitz, Phillip A.; Blanchard, Jeremy; Kimura, Marcia L.; Kurath, Dean E.

    2012-09-01

    One of the events postulated in the hazard analysis at the Waste Treatment and Immobilization Plant (WTP) and other U.S. Department of Energy (DOE) nuclear facilities, is a breach in process piping that produces aerosols with droplet sizes in the respirable range. The current approach for predicting the size and concentration of aerosols produced in a spray leak involves extrapolating from correlations published in the literature. These correlations are based on results obtained from small engineered spray nozzles using pure liquids with Newtonian fluid behavior. The narrow ranges of physical properties on which the correlations are based do not cover the wide range of slurries and viscous materials present in the WTP and across processing facilities in the DOE complex. Two key technical areas were identified where testing results were needed to improve the technical basis by reducing the uncertainty introduced by extrapolating existing literature results. The first technical need was to quantify the role of slurry particles in small breaches in which the slurry particles may plug and result in substantially reduced, or even negligible, respirable fraction formed by high pressure sprays. The second technical need was to determine the aerosol droplet size distribution and volume from prototypic breaches and fluids, specifically including sprays from larger breaches with slurries where data from the literature are largely absent. To address these technical areas, small- and large-scale test stands were constructed and operated with simulants to determine the aerosol release fractions and aerosol generation rates from a range of breach sizes and geometries. The properties of the simulants represented the range of properties expected in the WTP process streams and included water, sodium salt solutions, slurries containing boehmite or gibbsite, and a hazardous chemical simulant. The effect of anti-foam agents (AFA) was assessed with most of the simulants. Orifices

  3. Fetal origin of vascular aging

    Directory of Open Access Journals (Sweden)

    Shailesh Pitale

    2011-01-01

    Full Text Available Aging is increasingly regarded as an independent risk factor for development of cardiovascular diseases such as atherosclerosis and hypertension and their complications (e.g. MI and Stroke. It is well known that vascular disease evolve over decades with progressive accumulation of cellular and extracellular materials and many inflammatory processes. Metabolic syndrome, obesity and diabetes are conventionally recognized as risk factors for development of coronary vascular disease (CVD. These conditions are known to accelerate ageing process in general and vascular ageing in particular. Adverse events during intrauterine life may programme organ growth and favour disease later in life, popularly known as, ′Barker′s Hypothesis′. The notion of fetal programming implies that during critical periods of prenatal growth, changes in the hormonal and nutritional milieu of the conceptus may alter the full expression of the fetal genome, leading to permanent effects on a range of physiological.

  4. Plug-in Electric Vehicle Policy Effectiveness: Literature Review

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Yan [Argonne National Lab. (ANL), Argonne, IL (United States); Levin, Todd [Argonne National Lab. (ANL), Argonne, IL (United States); Plotkin, Steven E. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-05-01

    The U.S. federal government first introduced incentives for plug-in electric vehicles (PEVs) through the American Clean Energy and Security Act of 2009, which provided a tax credit of up to $7,500 for a new PEV purchase. Soon after, in December 2010, two mass-market PEVs were introduced, the plug-in hybrid electric vehicle (PHEV) Chevrolet Volt and the battery electric vehicle (BEV) Nissan LEAF. Since that time, numerous additional types of PEV incentives have been provided by federal and regional (state or city) government agencies and utility companies. These incentives cover vehicle purchases as well as the purchase and installation of electric vehicle supply equipment (EVSE) through purchase rebates, tax credits, or discounted purchase taxes or registration fees. Additional incentives, such as free high-occupancy vehicle (HOV) lane access and parking benefits, may also be offered to PEV owners. Details about these incentives, such as the extent to which each type is offered by region, can be obtained from the U.S. Department of Energy (DOE) Alternative Fuel Data Center (http://www.afdc.energy.gov/). In addition to these incentives, other policies, such as zero-emission vehicle (ZEV) mandates,1 have also been implemented, and community-scale federal incentives, such as the DOE PEV Readiness Grants, have been awarded throughout the country to improve PEV market penetration. This report reviews 18 studies that analyze the impacts of past or current incentives and policies that were designed to support PEV adoption in the U.S. These studies were selected for review after a comprehensive survey of the literature and discussion with a number of experts in the field. The report summarizes the lessons learned and best practices from the experiences of these incentive programs to date, as well as the challenges they face and barriers that inhibit further market adoption of PEVs. Studies that make projections based on future policy scenarios and those that focus solely

  5. Vascular Injury in Orthopedic Trauma.

    Science.gov (United States)

    Mavrogenis, Andreas F; Panagopoulos, George N; Kokkalis, Zinon T; Koulouvaris, Panayiotis; Megaloikonomos, Panayiotis D; Igoumenou, Vasilios; Mantas, George; Moulakakis, Konstantinos G; Sfyroeras, George S; Lazaris, Andreas; Soucacos, Panayotis N

    2016-07-01

    Vascular injury in orthopedic trauma is challenging. The risk to life and limb can be high, and clinical signs initially can be subtle. Recognition and management should be a critical skill for every orthopedic surgeon. There are 5 types of vascular injury: intimal injury (flaps, disruptions, or subintimal/intramural hematomas), complete wall defects with pseudoaneurysms or hemorrhage, complete transections with hemorrhage or occlusion, arteriovenous fistulas, and spasm. Intimal defects and subintimal hematomas with possible secondary occlusion are most commonly associated with blunt trauma, whereas wall defects, complete transections, and arteriovenous fistulas usually occur with penetrating trauma. Spasm can occur after either blunt or penetrating trauma to an extremity and is more common in young patients. Clinical presentation of vascular injury may not be straightforward. Physical examination can be misleading or initially unimpressive; a normal pulse examination may be present in 5% to 15% of patients with vascular injury. Detection and treatment of vascular injuries should take place within the context of the overall resuscitation of the patient according to the established principles of the Advanced Trauma Life Support (ATLS) protocols. Advances in the field, made mostly during times of war, have made limb salvage the rule rather than the exception. Teamwork, familiarity with the often subtle signs of vascular injuries, a high index of suspicion, effective communication, appropriate use of imaging modalities, sound knowledge of relevant technique, and sequence of surgical repairs are among the essential factors that will lead to a successful outcome. This article provides a comprehensive literature review on a subject that generates significant controversy and confusion among clinicians involved in the care of trauma patients. [Orthopedics. 2016; 39(4):249-259.]. PMID:27322172

  6. Vascular Gene Expression: A Hypothesis

    Directory of Open Access Journals (Sweden)

    Angélica Concepción eMartínez-Navarro

    2013-07-01

    Full Text Available The phloem is the conduit through which photoassimilates are distributed from autotrophic to heterotrophic tissues and is involved in the distribution of signaling molecules that coordinate plant growth and responses to the environment. Phloem function depends on the coordinate expression of a large array of genes. We have previously identified conserved motifs in upstream regions of the Arabidopsis genes, encoding the homologs of pumpkin phloem sap mRNAs, displaying expression in vascular tissues. This tissue-specific expression in Arabidopsis is predicted by the overrepresentation of GA/CT-rich motifs in gene promoters. In this work we have searched for common motifs in upstream regions of the homologous genes from plants considered to possess a primitive vascular tissue (a lycophyte, as well as from others that lack a true vascular tissue (a bryophyte, and finally from chlorophytes. Both lycophyte and bryophyte display motifs similar to those found in Arabidopsis with a significantly low E-value, while the chlorophytes showed either a different conserved motif or no conserved motif at all. These results suggest that these same genes are expressed coordinately in non- vascular plants; this coordinate expression may have been one of the prerequisites for the development of conducting tissues in plants. We have also analyzed the phylogeny of conserved proteins that may be involved in phloem function and development. The presence of CmPP16, APL, FT and YDA in chlorophytes suggests the recruitment of ancient regulatory networks for the development of the vascular tissue during evolution while OPS is a novel protein specific to vascular plants.

  7. Plant Vascular Biology and Agriculture

    Institute of Scientific and Technical Information of China (English)

    William J.Lucas

    2010-01-01

    @@ The evolution of animal and plant vascular systems played a pivotal role in the advancement from simple to complex organisms,through the provision of a delivery system for the distribution of components essential for both metabolism and growth.Interestingly,although these two vascular systems conform to the same generel rules of fluid dynamics(Murray1926;McCulloh et al.2003),the developmental mechanisms adopted by plants and animals,to generate these long-distance transport systems.have little in common.

  8. Vascular Function in Alzheimer's Disease and Vascular Dementia.

    Science.gov (United States)

    Tachibana, Hisatsugu; Washida, Kazuo; Kowa, Hisatomo; Kanda, Fumio; Toda, Tatsushi

    2016-08-01

    We investigated vascular functioning in patients with a clinical and radiological diagnosis of either Alzheimer's disease (AD) or vascular dementia (VaD) and examined a possible relationship between vascular function and cognitive status. Twenty-seven patients with AD, 23 patients with VaD, and 26 healthy control patients underwent measurements of flow-mediated dilation (FMD), ankle-brachial index (ABI), cardioankle vascular index (CAVI), and intima-media thickness (IMT). The FMD was significantly lower in patients with AD or VaD compared to controls. There were no significant differences in ABI, CAVI, or IMT among the 3 groups. A significant correlation was found between Mini-Mental State Examination (MMSE) scores and FMD. Furthermore, a multiple regression analysis revealed that FMD was significantly predicted by MMSE scores. These results suggest that endothelial involvement plays a role in AD pathogenesis, and FMD may be more sensitive than other surrogate methods (ABI, CAVI, and IMT) for detecting early-stage atherosclerosis and/or cognitive decline. PMID:27284205

  9. Computational analysis on plug-in hybrid electric motorcycle chassis

    Science.gov (United States)

    Teoh, S. J.; Bakar, R. A.; Gan, L. M.

    2013-12-01

    Plug-in hybrid electric motorcycle (PHEM) is an alternative to promote sustainability lower emissions. However, the PHEM overall system packaging is constrained by limited space in a motorcycle chassis. In this paper, a chassis applying the concept of a Chopper is analysed to apply in PHEM. The chassis 3dimensional (3D) modelling is built with CAD software. The PHEM power-train components and drive-train mechanisms are intergraded into the 3D modelling to ensure the chassis provides sufficient space. Besides that, a human dummy model is built into the 3D modelling to ensure the rider?s ergonomics and comfort. The chassis 3D model then undergoes stress-strain simulation. The simulation predicts the stress distribution, displacement and factor of safety (FOS). The data are used to identify the critical point, thus suggesting the chassis design is applicable or need to redesign/ modify to meet the require strength. Critical points mean highest stress which might cause the chassis to fail. This point occurs at the joints at triple tree and bracket rear absorber for a motorcycle chassis. As a conclusion, computational analysis predicts the stress distribution and guideline to develop a safe prototype chassis.

  10. The plug-based nanovolume Microcapillary Protein Crystallization System (MPCS)

    International Nuclear Information System (INIS)

    The Microcapillary Protein Crystallization System (MPCS) is a new protein-crystallization technology used to generate nanolitre-sized crystallization experiments for crystal screening and optimization. Using the MPCS, diffraction-ready crystals were grown in the plastic MPCS CrystalCard and were used to solve the structure of methionine-R-sulfoxide reductase. The Microcapillary Protein Crystallization System (MPCS) embodies a new semi-automated plug-based crystallization technology which enables nanolitre-volume screening of crystallization conditions in a plasticware format that allows crystals to be easily removed for traditional cryoprotection and X-ray diffraction data collection. Protein crystals grown in these plastic devices can be directly subjected to in situ X-ray diffraction studies. The MPCS integrates the formulation of crystallization cocktails with the preparation of the crystallization experiments. Within microfluidic Teflon tubing or the microfluidic circuitry of a plastic CrystalCard, ∼10–20 nl volume droplets are generated, each representing a microbatch-style crystallization experiment with a different chemical composition. The entire protein sample is utilized in crystallization experiments. Sparse-matrix screening and chemical gradient screening can be combined in one comprehensive ‘hybrid’ crystallization trial. The technology lends itself well to optimization by high-granularity gradient screening using optimization reagents such as precipitation agents, ligands or cryoprotectants

  11. Status of ITER TBM port plug conceptual design and analyses

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byoung Yoon, E-mail: byoungyoon.kim@iter.org [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Sabourin, Flavien; Merola, Mario; Giancarli, Luciano [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Villari, R. [ENEA Frascati (Italy); Di Maio, P.A. [University of Palermo (Italy); Lucca, F.; Marconi, M. [LTCalcoli, Piazza Prinetti 26/B, 23807 Merate (Italy); Levesy, B. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France)

    2014-10-15

    Highlights: •ITER TBM PP conceptual design with two dummy TBMs was summarized. •TBM PP shielding capability was assessed to allow hands-on operation. •TBM PP steady state hydraulic performance was investigated. •EM and structural analysis was performed to evaluate structural margin. -- Abstract: The test blanket module port plug (TBM PP) consists of a TBM frame and two TBM-sets. However, at any time of the ITER operation, a TBM set can be replaced by a dummy TBM. The frame provides a standardized interface with the vacuum vessel (VV)/port structure and provides thermal isolation from the shield blanket. As one of the plasma-facing components, it shall withstand heat loads while at the same time provide adequate neutron shielding for the VV and magnet coils. The frame design shall provide a stable engineering solution to hold TBM-sets and also provide a mean for rapid remote handling replacement and refurbishment. This paper presents main design features of the conceptual design of TBM PP with two dummy TBMs. Also analysis results are summarized to evaluate shielding, hydraulic, and thermal and structural performances of the TBM PP design.

  12. Depth discrete soil plug analytical results supporting DUS remediation

    International Nuclear Information System (INIS)

    In support of the installation of the thermocouples and Electrical Resistivity Tomography (ERT) sensor arrays and the injection/extraction well system for the Dynamic Underground Stripping (DUS) remediation at the 311-M Solvent Storage Tank Pad Area, SRTC collected soil plug samples as part of the drilling operations. These samples were analyzed by GC headspace method. The principal analytes were trichloroethylene (TCE) and tetrachloroethylene (PCE). In general, this effort, in combination with the soil concentration measurements by IT Corporation, provides an initial assessment of the pre-operational conditions at the DUS site. A specific objective of the SRTC data collection is to supplement and confirm the IT sampling. Concentrations indicating DNAPL in the immediate area were found in boring TM11 in the shallow vadose zone. The remaining four borings indicate much lower levels of TCE and PCE. PCE is the predominant contaminant at this location. The data indicate DNAPL is present in the vicinity of the 311-M Solvent Storage Tank Pad. The precise volume and spatial distribution cannot be determined from the SRTC sample results due to the limited data set

  13. Status of ITER TBM port plug conceptual design and analyses

    International Nuclear Information System (INIS)

    Highlights: •ITER TBM PP conceptual design with two dummy TBMs was summarized. •TBM PP shielding capability was assessed to allow hands-on operation. •TBM PP steady state hydraulic performance was investigated. •EM and structural analysis was performed to evaluate structural margin. -- Abstract: The test blanket module port plug (TBM PP) consists of a TBM frame and two TBM-sets. However, at any time of the ITER operation, a TBM set can be replaced by a dummy TBM. The frame provides a standardized interface with the vacuum vessel (VV)/port structure and provides thermal isolation from the shield blanket. As one of the plasma-facing components, it shall withstand heat loads while at the same time provide adequate neutron shielding for the VV and magnet coils. The frame design shall provide a stable engineering solution to hold TBM-sets and also provide a mean for rapid remote handling replacement and refurbishment. This paper presents main design features of the conceptual design of TBM PP with two dummy TBMs. Also analysis results are summarized to evaluate shielding, hydraulic, and thermal and structural performances of the TBM PP design

  14. Plug-in privacy for Smart Metering billing

    CERN Document Server

    Jawurek, Marek; Kerschbaum, Florian

    2010-01-01

    Smart Metering is a concept that allows to collect fine-grained consumption profiles from customers by replacing traditional electricity meters with Smart Meters in customers' households. The recorded consumption profile is the basis for the calculation of time-dependent tariffs but also allows deduction of the inhabitant's personal schedules and habits. The current reporting of such consumption profiles only protects this data from 3rd parties but falls short to protect the customer's privacy from illegitimate abuse by the supplier itself. We propose a privacy-preserving profile reporting protocol that enables billing for time-dependent tariffs without disclosing the actual data of the consumption profile to the supplier. Our approach relies on a zero-knowledge proof based on Pedersen Commitments performed by a plug-in privacy component that is put into the communication link between Smart Meter and supplier's back-end systems and requires no change to Smart Meter hardware and only little change to the softw...

  15. Episodic air quality impacts of plug-in electric vehicles

    Science.gov (United States)

    Razeghi, Ghazal; Carreras-Sospedra, Marc; Brown, Tim; Brouwer, Jack; Dabdub, Donald; Samuelsen, Scott

    2016-07-01

    In this paper, the Spatially and Temporally Resolved Energy and Environment Tool (STREET) is used in conjunction with University of California Irvine - California Institute of Technology (UCI-CIT) atmospheric chemistry and transport model to assess the impact of deploying plug-in electric vehicles and integrating wind energy into the electricity grid on urban air quality. STREET is used to generate emissions profiles associated with transportation and power generation sectors for different future cases. These profiles are then used as inputs to UCI-CIT to assess the impact of each case on urban air quality. The results show an overall improvement in 8-h averaged ozone and 24-h averaged particulate matter concentrations in the South Coast Air Basin (SoCAB) with localized increases in some cases. The most significant reductions occur northeast of the region where baseline concentrations are highest (up to 6 ppb decrease in 8-h-averaged ozone and 6 μg/m3 decrease in 24-h-averaged PM2.5). The results also indicate that, without integration of wind energy into the electricity grid, the temporal vehicle charging profile has very little to no effect on urban air quality. With the addition of wind energy to the grid mix, improvement in air quality is observed while charging at off-peak hours compared to the business as usual scenario.

  16. Automated WWER steam generator eddy current testing and plugging control system

    International Nuclear Information System (INIS)

    The structural architecture of the system contains three main components which are described as follows: Manipulator Guidance System; Eddy Current Testing System; Plugging System. The manipulator system has the task to position the end-effectors to the desired tube position. When the final position is reached, the Eddy Current testing system performs data acquisition. In case defects are found, the plugging system performs tube plug installment. Each system is composed of 3 layers. The first layer is the hardware layer consisting of motors driving the effectors along with sensors needed to obtain the positioning data, pusher motors used to push the test probes into tubes of the WWER steam generator, and plugging hardware tool. The second layer is the control box performing basic monitoring and control routines as an interconnection between first and third layer. The highest layer is the control software, running on the PC, which is used as a human-machine-interface.(author)

  17. Plug-and-Play Compatibility for CubeSat Attitude Determination and Control Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The development of Plug-and-play Compatibility for CubeSat Attitude Determination and Control Systems (ADACS) is proposed. Existing Maryland Aerospace (MAI) ADACS...

  18. The valve effect of the carbide interlayer of an electric resistance plug

    International Nuclear Information System (INIS)

    The welded electric resistance plug (ERP) usually contains a carbide interlayer at the plug-carbon material interface. The interlayer forms during welding the contact metallic alloy with the carbon material when the oxide films of the alloy are reduced on the interface surface by carbon to the formation of carbides and the surface layer of the plug material dissolves carbon to saturation. Subsequently, during solidification of the plug material it forms carbides with the alloy components. The structural composition of the carbide interlayer is determined by the chemical composition of the contact alloy. In alloys developed by the author and his colleagues the carbide forming elements are represented in most cases by silicon and titanium and, less frequently, by chromium and manganese. Therefore, the carbide interlayers in the ERP consisted mainly of silicon and titanium carbides

  19. Plug-and-Play Star Sensor for Rapid Spacecraft Integration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Microcosm, with Space Micro., and HRP Systems will design a plug-and-play (PnP) star sensor for small satellites. All three companies are well experienced in...

  20. Creating the Semipar custom plug-in for the jMRUI platform

    International Nuclear Information System (INIS)

    This work is related to the FAST jMRUI signal-analysis package. Recently this package has been refactored as a plug-in platform, allowing end-users to add their own features. Here we describe the creation of a jMRUI custom plug-in named Semipar. This plug-in integrates into jMRUI a two-NLLS criterion that we have recently developed for handling the quantitation of in vivo MRS signals with an unknown common lineshape. The Semipar plug-in was tested by applying it to a simulated MRS signal. This signal was generated by using the various methods and tools of the jMRUI platform. It was found that—depending on the SNR of the signal—the Semipar approach can improve the MRS quantitation results

  1. The impact of NPP Krsko steam generator tube plugging on minimum DNBR at nominal conditions

    International Nuclear Information System (INIS)

    Typically, steam generator tube plugging (SGTP) both decreases the reactor coolant system (RCS) flow rate and the heat transfer surface area of the steam generator. At a constant thermal power and vessel outlet temperature, as tube plugging increases, the vessel average temperature, vessel inlet temperature and steam generator secondary side steam pressure decrease. This paper presents the analysis of impact of SGTP on Minimum Departure from Nucleate Boiling Ratio (MDNBR) at NPP Krsko (NEK), using the Improved Thermal Design Procedure (ITDP), WRB-1 correlation, and COBRA-III-C computer code. No credit was given to high plugging percentage region power reduction resulting from turbine volumetric flow limitations. MDNBR is found to be decreasing with increasing plugging, but not under the limiting values. (author)

  2. Plug-and-Play Star Sensor for Rapid Spacecraft Integration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Microcosm, with partners Space Micro and HRP Systems, will design, build, and test a plug-and play (PnP) star sensor for small satellites, achieving TRL 6 at the...

  3. Quantifying the effect of plug-flat color on medium-surface temperatures

    International Nuclear Information System (INIS)

    Medium-surface temperature of black, gray, and white plug sheets was measured with thermocouples and an infrared camera. During the night, there were no medium-surface temperature differences between the plug flats; however, medium-surface temperature was 2 to 3 °C below air temperature. Medium-surface temperature increased as solar radiation (280 to 3000 nm) increased. About 80 W of solar radiation/m2 was incident on the plug-flat surface before medium-surface temperature equaled air temperature. Medium-surface temperature in the black, gray, and white flats was 6.3, 6.1, and 5.3 °C above air temperature, respectively, when 300 W of solar radiation/m2 (30% of the maximum solar radiation during the summer) was incident on the medium surface. Thus, incident solar radiation has a greater effect on medium surface temperature than plug-flat color. (author)

  4. Plug-Load Control and Behavioral Change Research in GSA Office Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Metzger, I.; Cutler, D.; Sheppy, M.

    2012-10-01

    The U.S. General Services Administration (GSA) owns and leases over 354 million square feet (ft2) of space in over 9,600 buildings [1]. GSA is a leader among federal agencies in aggressively pursuing energy efficiency (EE) opportunities for its facilities and installing renewable energy (RE) systems to provide heating, cooling, and power to these facilities. According to several energy assessments of GSA's buildings conducted by the National Renewable Energy Laboratory (NREL), plug-loads account for approximately 21% of the total electricity consumed within a standard GSA Region 3 office building. This study aims to provide insight on how to effectively manage plug-load energy consumption and attain higher energy and cost savings for plug-loads. As GSA improves the efficiency of its building stock, plug-loads will become an even greater portion of its energy footprint.

  5. Pilot Study of a Plug Load Management System: Preparing for Sustainability Base

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA Ames Research Center’s Sustainability Base is a new 50,000 sq. ft. high-performance office building targeting a LEED Platinum rating. Plug loads are expected...

  6. Nonlinear analytical models for interfacial plug stresses in creeping salt formation

    International Nuclear Information System (INIS)

    The disposal of high level nuclear waste material deep within the confines of a rock-salt formation is being considered for the safe disposal of radioactive material. Access boreholes, shafts, tunnels, and drifts used for transporting the waste material must be sealed after the waste has been stored. Expansive self-stressing concrete plugs are being field tested. Analytical and numerical simulation models are presented in this paper which predict the nonlinear time dependent behavior of an expanding plug in a creeping environment heavily dependent on the storage room temperature. Extensive sensitivity and parametric studies have been performed. These studies show that the interfacial strains between the concrete plug and surrounding rock-salt are largely influenced by: (a) the time dependent variation in the early modulus of concrete; (b) creep and shrinkage behavior of concrete; (c) creep and borehole convergence behavior of rock-salt; and (d) expansivity characteristics of the plug material

  7. Ongoing Technology and Developing Trend of Ar-blowing Purging Plug

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    An introduction of the ongoing technology of ar-gon-blowing purging plugs in China was presented in this work.Gel powders were used as starting materials to enhance the high temperature mechanical properties of the purging plugs.Composite purging plug adopting ex-trusion formed gas-purging bar and slit had its surface structural design improved,which enhanced the resist-ances to thermal shock and molten steel penetration,prolonging the service life.In addition,the safety Was greatly improved by upgrading the framework and pro-duction process,enhancing the resistance to breakout.It is indicated that the developing trend is to produce pur-ging plugs of longer service life and better gas purging rate with different starting materials and structure de-signs to meet the requirements of various metallurgical processes.

  8. Wear on Plugged Tube due to the Foreign Objects on the Secondary Side of Steam Generator

    International Nuclear Information System (INIS)

    In this paper, the changes of the tube frequency and amplitude are introduced before and after plugging. The amplitude of the bottom span for the steam generator tube is not much changed after tube plugging. Moreover, the contact force between the plugged tube and the foreign object is the same as that of intact tube and the foreign object. However, the frequencies of plugged tubes are about 9∼12% higher than those of intact tubes. That means the wear due to the foreign object would be accelerated after the tube plugging. Therefore, the tube stabilizer should be installed when the tube is plugged due to the foreign object wear. The tube wall of steam generator is a pressure boundary between the coolant of the primary system and the feedwater of the secondary system. It is very important to insure the structural integrity of the tubes because the radioactive coolant is flow into the feedwater due to the pressure difference as the result of tube failure. The degradations of steam generator tubes are corrosion, wear, fatigue and foreign object wear, etc. The foreign object wear is one of mechanical degradation due to materials flew into the secondary side of steam generator. The steam generator tubes, estimated not to insure structural integrity from the results of the nondestructive evaluation such as eddy current test and visual inspection, are excluded from the service with plugging. However, the tube wear is still being progressed after the plugging because the relative motion between the tube and structure is still existed due to the secondary side flow in the steam generator. If the tube is completely cut because of the degradation, the tube can be a stress or of failure of tubes around the plugged tube. The contact force between the structure and tube is lowered as the wear is progressed. However, the contact force between the foreign object and tube is not changed as the wear is progressed. Therefore, the structural integrity of tubes around the foreign

  9. Toyota Prius Plug-In HEV: A Plug-In Hybrid Electric Car in NREL's Advanced Technology Vehicle Fleet (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2011-10-01

    This fact sheet highlights the Toyota Prius plug-in HEV, a plug-in hybrid electric car in the advanced technology vehicle fleet at the National Renewable Energy Laboratory (NREL). In partnership with the University of Colorado, NREL uses the vehicle for grid-integration studies and for testing new hardware and charge-management algorithms. NREL's advanced technology vehicle fleet features promising technologies to increase efficiency and reduce emissions without sacrificing safety or comfort. The fleet serves as a technology showcase, helping visitors learn about innovative vehicles that are available today or are in development. Vehicles in the fleet are representative of current, advanced, prototype, and emerging technologies.

  10. Challenges after the first decade of transcatheter aortic valve replacement: focus on vascular complications, stroke, and paravalvular leak.

    Science.gov (United States)

    Reidy, Christopher; Sophocles, Aris; Ramakrishna, Harish; Ghadimi, Kamrouz; Patel, Prakash A; Augoustides, John G T

    2013-02-01

    Transcatheter aortic valve replacement (TAVR) is entering its second decade. Three major clinical challenges have emerged from the first decade of experience: vascular complications, stroke, and paravalvular leak (PVL). Major vascular complications remain common and independently predict major bleeding, transfusion, renal failure, and mortality. Although women are more prone to vascular complications, overall they have better survival than men. Further predictors of major vascular complications include heavily diseased femoral arteries and operator experience. Strategies to minimize vascular complications include a multimodal approach and sleeker delivery systems. Although cerebral embolism is very common during TAVR, it mostly is asymptomatic. Major stroke independently predicts prolonged recovery and increased mortality. Identified stroke predictors include functional disability, previous stroke, a transapical approach, and atrial fibrillation. Embolic protection devices are in development to mitigate the risk of embolic stroke after TAVR. PVL is common and significantly decreases survival. Undersizing of the valve prosthesis can be minimized with 3-dimensional imaging by computed tomography or echocardiography to describe the elliptic aortic annulus accurately. The formal grading of PVL severity in TAVR is based on its percentage of the circumferential extent of the aortic valve annulus. Further emerging management strategies for PVL include a repositionable valve prosthesis and transcatheter plugging. The first decade of TAVR has ushered in a new paradigm for the multidisciplinary management of valvular heart disease. The second decade likely will build on this wave of initial success with further significant innovations. PMID:23141627

  11. Valuation of plug-in vehicle life-cycle air emissions and oil displacement benefits

    OpenAIRE

    Michalek, Jeremy J.; Chester, Mikhail; Jaramillo, Paulina; Samaras, Constantine; Shiau, Ching-Shin Norman; Lester B. Lave

    2011-01-01

    We assess the economic value of life-cycle air emissions and oil consumption from conventional vehicles, hybrid-electric vehicles (HEVs), plug-in hybrid-electric vehicles (PHEVs), and battery electric vehicles in the US. We find that plug-in vehicles may reduce or increase externality costs relative to grid-independent HEVs, depending largely on greenhouse gas and SO2 emissions produced during vehicle charging and battery manufacturing. However, even if future marginal damages from emissions ...

  12. City of Las Vegas Plug-in Hybrid Electric Vehicle Demonstration Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-12-31

    The City of Las Vegas was awarded Department of Energy (DOE) project funding in 2009, for the City of Las Vegas Plug-in Hybrid Electric Vehicle Demonstration Program. This project allowed the City of Las Vegas to purchase electric and plug-in hybrid electric vehicles and associated electric vehicle charging infrastructure. The City anticipated the electric vehicles having lower overall operating costs and emissions similar to traditional and hybrid vehicles.

  13. Hybrid and Plug-In Electric Vehicles (Spanish Version); Clean Cities, Energy Efficiency & Renewable Energy (EERE)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-08-01

    This is a Spanish-language brochure about hybrid and plug-in electric vehicles, which use electricity as their primary fuel or to improve the efficiency of conventional vehicle designs. These vehicles can be divided into three categories: hybrid electric vehicles (HEVs), plug-in hybrid electric vehicles (PHEVs), all-electric vehicles (EVs). Together, they have great potential to cut U.S. petroleum use and vehicle emissions.

  14. LTC And Shunt Capacitor Switching In Smart Grid: Sensitivity To Plug-In Electric Vehicle Forecasts

    OpenAIRE

    Sara Deilami

    2015-01-01

    Optimal scheduling of transformer load tap changer (LTC) and switched shunt capacitors (SSCs) in smart grid (SG) with plug-in electric vehicles (PEVs) and nonlinear loads can be performed to reduce system losses, node voltage fluctuations and total harmonic distortion (THD). This paper investigates the effects of vehicles’ plug-in time forecast errors on performance of LTC and SSCs switching. First, a genetic algorithm (GA) is used to determine the optimal switching schedules with...

  15. Plug-in de procesado visual (OpenCV) en OpenDomo OS

    OpenAIRE

    Herrera Castro, Alexander

    2015-01-01

    Este proyecto consiste en el diseño y desarrollo de un plug-in que permita usar el sistema de procesado de imagen OpenCV desde el sistema operativo OpenDomo OS. Aquest projecte consisteix en el disseny i desenvolupament d'un plug-in que permeti utilitzar el sistema de processament d'imatge OpenCV des del sistema operatiu OpenDomo OS. Master thesis for the Free Software program.

  16. Botulinum neurotoxin type A versus punctal plug insertion in the management of dry eye disease

    OpenAIRE

    Bukhari, Amal A.

    2014-01-01

    Purpose: To compare the efficacies of punctal plug insertion and Botulinum toxin injection in dry eye disease not responding to topical medications. Materials and Methods: A non-controlled randomized clinical trial of two parallel groups of 60 dry eye patients seen in the clinic not responding to topical medications were divided into two groups. One group received punctal plugs and the other group received Botulinum toxin injections to prevent lacrimal tear drainage. Results: Of a tot...

  17. Effect of the duty cycle on the spark-plug plasma synthetic jet actuator

    OpenAIRE

    Seyhan Mehmet; Akansu Yahya Erkan; Karakaya Fuat; Yesildag Cihan; Akbıyık Hürrem

    2016-01-01

    A promising novel actuator called Spark-Plug Plasma Synthetic Jet (SPSJ) has been developed in Atmospheric Plasma Research Laboratory at Niğde University. It generates electrothermally high synthetic jet velocity by using high voltage. SPSJ actuator can be utilized to be an active flow control device having some advantages such as no moving parts, low energy consumption and easy to integrate the system. This actuator consists of two main components: semi-surface spark plug (NGK BUHW) as an an...

  18. Cystine Plug and Other Novel Mechanisms of Large Mechanical Stability in Dimeric Proteins

    Science.gov (United States)

    Sikora, Mateusz; Cieplak, Marek

    2012-11-01

    We identify three dimeric proteins whose mechanostability is anisotropic and should exceed 1 nN along some directions. They come with distinct mechanical clamps: either shear-based, or involving a cystine slipknot, or due to dragging of a cystine plug through a cystine ring. The latter two mechanisms are topological in nature; the cystine plug mechanism has not yet been discussed but it turns out to provide the largest resistance to stretching. Its possible applications in elastomers are discussed.

  19. Cystine plug and other novel mechanisms of large mechanical stability in dimeric proteins

    OpenAIRE

    Sikora, Mateusz; Cieplak, Marek

    2012-01-01

    We identify three dimeric proteins whose mechanostability is anisotropic and should exceed 1 nN along some directions. They come with distinct mechanical clamps: shear-based, involving a cystine slipknot, and due to dragging of a cystine plug through a cystine ring. The latter two mechanisms are topological in nature and the cystine plug mechanism has not yet been discussed but it turns out to provide the largest resistance to stretching. Its possible applications in elastomers are discussed.

  20. Computational modeling of unsteady surfactant-laden liquid plug propagation in neonatal airways

    OpenAIRE

    Olgac, Ufuk; Muradoğlu, Metin

    2013-01-01

    Surfactant-free and surfactant-laden liquid plug propagation in neonatal airways in various generations representing the upper and lower airways are investigated computationally using a finite-difference/front-tracking method. Emphasis is placed on the unsteady surfactant-laden plug propagation as a model for Surfactant Replacement Therapy (SRT) and airway reopening. The numerical method is designed to solve the evolution equations of the interfacial and bulk surfactant concentrations coupled...

  1. Ford Plug-In Project: Bringing PHEVs to Market Demonstration and Validation Project

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-12-31

    This project is in support of our national goal to reduce our dependence on fossil fuels. By supporting efforts that contribute toward the successful mass production of plug-in hybrid electric vehicles, our nation’s transportation-related fuel consumption can be offset with energy from the grid. Over four and a half years ago, when this project was originally initiated, plug-in electric vehicles were not readily available in the mass marketplace. Through the creation of a 21 unit plug-in hybrid vehicle fleet, this program was designed to demonstrate the feasibility of the technology and to help build cross-industry familiarity with the technology and interface of this technology with the grid. Ford Escape PHEV Demonstration Fleet 3 March 26, 2014 Since then, however, plug-in vehicles have become increasingly more commonplace in the market. Ford, itself, now offers an all-electric vehicle and two plug-in hybrid vehicles in North America and has announced a third plug-in vehicle offering for Europe. Lessons learned from this project have helped in these production vehicle launches and are mentioned throughout this report. While the technology of plugging in a vehicle to charge a high voltage battery with energy from the grid is now in production, the ability for vehicle-to-grid or bi-directional energy flow was farther away than originally expected. Several technical, regulatory and potential safety issues prevented progressing the vehicle-to-grid energy flow (V2G) demonstration and, after a review with the DOE, V2G was removed from this demonstration project. Also proving challenging were communications between a plug-in vehicle and the grid or smart meter. While this project successfully demonstrated the vehicle to smart meter interface, cross-industry and regulatory work is still needed to define the vehicle-to-grid communication interface.

  2. Vascular complications in glioma patients.

    Science.gov (United States)

    Le Rhun, Emilie; Perry, James R

    2016-01-01

    Vascular complications in patients with glioma most commonly include venous and arterial thromboembolism; however, treatment-induced vasculopathies are also problematic, especially in long-term survivors. The interactions between treatment such as radiation and chemotherapy, the coagulation cascade, endothelium, and regulators of angiogenesis are complex, drive glioma growth and invasion, and create common management problems in the clinic. We review the incidence of thrombotic complications in glioma, the biology of the coagulome as related to glioma progression, prevention and treatment of thrombosis, the role of anticoagulants as anticancer therapy, and vascular complications such as ischemic stroke and intracranial bleeding. The coagulation cascade is intimately involved in cancer-related thrombosis, glioma progression, and vascular complications of glioma therapy. Tissue factor is the principal initiator of coagulation and is upregulated in a glioma subtype-specific fashion. Short-term (perioperative) antithrombotic prophylaxis is effective, but long-term anticoagulation, although attractive, is not routinely indicated. Most patients with symptomatic venous thromboembolism can be safely anticoagulated, including those on anti-vascular endothelial growth factor therapeutics such as bevacizumab. Initial therapy should include low-molecular-weight heparin, and protracted anticoagulant treatment, perhaps indefinitely, is indicated. Many complex interactions resulting in vessel wall injury can lead to ischemic stroke, intracranial and intratumoral hemorrhage, and long-term sequelae such as cognitive impairment. PMID:26948359

  3. Real-Time Occupant Based Plug-in Device Control Using ICT in Office Buildings

    Directory of Open Access Journals (Sweden)

    Woo-Bin Bae

    2016-03-01

    Full Text Available The purpose of this study is to reduce the unnecessary plug loads used by computers, monitors, and computer peripheral devices, all of which account for more than 95% of the entire plug loads of an office building. To this end, an occupant-based plug-in device control (OBC-P software was developed. The OBC-P software collects real-time information about the presence or absence of occupants who are connected to the access point through the Wifi and controls the power of monitors or computers, while a standby power off device controls computer peripheral devices. To measure the plug load saving of the occupant-based plug-in device control, an experiment was conducted, targeting 10 occupants of three research labs of the graduate school, for two weeks. The experiment results showed that it could save the plug loads of monitors and computer peripheral devices by 15% in the Awake mode, and by 26% in the Sleep mode.

  4. Comprehensive Review of the Literature on Existing Punctal Plugs for the Management of Dry Eye Disease.

    Science.gov (United States)

    Jehangir, Naz; Bever, Greg; Mahmood, S M Jafar; Moshirfar, Majid

    2016-01-01

    Numerous designs of punctal and canalicular plugs are available on the market. This variety presents challenges to ophthalmologists when choosing punctal plugs for the management of various ocular conditions. The aim of this literature review is to provide a classification system for lacrimal occlusive devices based on their location and duration of action as well as to identify different characteristics of each one of them. We want to give a comprehensive overview on punctal and canalicular plugs including their manufacturing companies, indications, and complications that have been reported in various articles. PubMed and Google Scholar were used to identify articles written in English as well as few articles written in Japanese, Chinese, Slovak, and Spanish that had abstracts in English. Nine different companies that manufacture punctal and canalicular plugs were identified and their plugs were included in this review. Punctal and canalicular plugs are used in the management of various ocular conditions including dry eye disease and punctal stenosis as well as in ocular drug delivery. Although they are a relatively safe option, associated complications have been reported in the literature such as infection, allergic reaction, extrusion, and migration. PMID:27088009

  5. Installation technique of the in-pile plug assembly for the neutron guide system at HANARO

    International Nuclear Information System (INIS)

    The research reactor HANARO in Korea will be equipped with a neutron guide system, in order to transport cold neutrons from the cold neutron source to the neutron scattering instruments in the neutron guide hall near the reactor building. The neutron guide system of HANARO consists of the in-pile plug assembly, the primary shutter, and out-of-pile neutron guides with dedicated secondary shutters. Functions of the in-pile plug assembly are to shield the reactor environment from a nuclear radiation and to support the neutron guides and maintain them precisely oriented. It is most important for the constructing of the neutron guide system to install new in-pile plug assembly with neutron guides precisely at the beam port of the reactor in radiation environment. The installation tool was developed by KAERI, which enables the removal of old in-pile plug and the installation of the new in-pile plug assembly or the guide cassette under radiation shielding. This paper presents the installation technique of the inpile plug assembly using this newly developed tool

  6. Gripping tool for the ITER upper port plug RH extraction/insertion

    International Nuclear Information System (INIS)

    Highlights: •The gripping tool is based on only one gripping point centred at the plug bottom. •The gripping tool should allow the relative displacement in the gripping point to absorb the misalignment between plug and tractor. •The gripping tool needs to withstand around 100/30 kN during the plug extraction/insertion. •The gripping tool should rely on visual control and it has to avoid force feed-back. •The comparison between the features of several gripping tool concepts is assessed. -- Abstract: The conceptual design of several gripping tools and their mechanical interfaces is being carried out for the ITER ECH UPP within the WP10-GOTRH programme. EFDA finances the GOT RH (Goal Oriented Training Programme for Remote Handling). The purpose of this paper is to introduce new concepts of gripping tools for the plug extraction/insertion in the upper port of ITER. All these gripping tools are designed according to IO input data and geometrical constraints. The gripping tools have to be able to extract/insert the plug in the scenario of maximum misalignment between the plug and the tractor. The paper also defines the functional requirements the gripping tools need to comply with. The requirements and input data are verified and validated through 3D simulation with Catia mock-ups of the gripping tools. The strengths and weaknesses of each gripping tool model are compared

  7. The oscillatory motion of a surfactant-laden liquid plug in a 2D-channel

    Science.gov (United States)

    Fujioka, Hideki; Grotberg, James B.

    2004-11-01

    Liquid plugs can form in the lung's small airways near the end of expiration. This happens more frequently when the amount of pulmonary surfactant is reduced. In medical treatments such as surfactant replacement therapy, partial liquid ventilation, and drug delivery, the formation of plugs in an airway is important to deliver the instilled liquid uniformly throughout the lung. In this study, we investigate numerically the oscillatory motion of a surfactant-laden liquid plug within a two-dimensional channel lined by a thin liquid film. The viscosity of both the left and right air phases is assumed to be negligible, so that the only fluid dynamics of the liquid phase is considered. The plug motion is regulated by the flow rate in the left air phase, which is prescribed as a sinusoidal function of time. The pressure drop between the left and right air phases varies for time with a different phase of the flow rate. The plug length and the film thickness oscillate with an average value during a cycle. These behaviors changes by system parameters, Reynolds number, Womersley number, Capillary number, and surfactant properties. The significance of this study on mechanical stresses acting on airway epithelial cells caused by the motion of a liquid plug during normal breath, conventional or high-frequency ventilation is discussed. Supported by NIH grant HL41126, NASA grant NAG3-2740.

  8. Comprehensive Review of the Literature on Existing Punctal Plugs for the Management of Dry Eye Disease

    Science.gov (United States)

    Jehangir, Naz; Bever, Greg; Mahmood, S. M. Jafar; Moshirfar, Majid

    2016-01-01

    Numerous designs of punctal and canalicular plugs are available on the market. This variety presents challenges to ophthalmologists when choosing punctal plugs for the management of various ocular conditions. The aim of this literature review is to provide a classification system for lacrimal occlusive devices based on their location and duration of action as well as to identify different characteristics of each one of them. We want to give a comprehensive overview on punctal and canalicular plugs including their manufacturing companies, indications, and complications that have been reported in various articles. PubMed and Google Scholar were used to identify articles written in English as well as few articles written in Japanese, Chinese, Slovak, and Spanish that had abstracts in English. Nine different companies that manufacture punctal and canalicular plugs were identified and their plugs were included in this review. Punctal and canalicular plugs are used in the management of various ocular conditions including dry eye disease and punctal stenosis as well as in ocular drug delivery. Although they are a relatively safe option, associated complications have been reported in the literature such as infection, allergic reaction, extrusion, and migration. PMID:27088009

  9. Fiscal year 1995 well plugging and abandonment program Y-12 Plant, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    This report is a synopsis of the progress of the well plugging and abandonment program at the Y-12 Plant, Oak Ridge, Tennessee, from September 1994 through August 1995. A total of 67 wells, piezometers, and borings were plugged and abandoned during the period of time covered in this report. All wells and borings were plugged and abandoned if (1) its construction did not meet current standards (substandard construction); (2) it was irreparably damaged or had deteriorated beyond practical repair; (3) its location interfered with or otherwise impeded site operations, construction, or closure activities; or (4) special circumstances existed as defined on a case-by-case basis and approved by the Y-12 Plant Groundwater Protection Program (GWPP) Manager. This summary report contains: general geologic setting of the Y-12 Plant and vicinity; discussion of well plugging and abandonment methods, grouting procedures, and waste management practices (a Waste Management Plan for Drilling Activities is included in Appendix C); summaries of plugging and abandonment activities at each site; and quality assurance/quality control (QA/QC) and health and safety protocols used during the FY 1995 Plugging and Abandonment Program

  10. Pediatric central nervous system vascular malformations

    International Nuclear Information System (INIS)

    Pediatric central nervous system (CNS) vascular anomalies include lesions found only in the pediatric population and also the full gamut of vascular lesions found in adults. Pediatric-specific lesions discussed here include infantile hemangioma, vein of Galen malformation and dural sinus malformation. Some CNS vascular lesions that occur in adults, such as arteriovenous malformation, have somewhat distinct manifestations in children, and those are also discussed. Additionally, children with CNS vascular malformations often have associated broader vascular conditions, e.g., PHACES (posterior fossa anomalies, hemangioma, arterial anomalies, cardiac anomalies, eye anomalies and sternal anomalies), hereditary hemorrhagic telangiectasia, and capillary malformation-arteriovenous malformation syndrome (related to the RASA1 mutation). The treatment of pediatric CNS vascular malformations has greatly benefited from advances in endovascular therapy, including technical advances in adult interventional neuroradiology. Dramatic advances in therapy are expected to stem from increased understanding of the genetics and vascular biology that underlie pediatric CNS vascular malformations. (orig.)

  11. Pediatric central nervous system vascular malformations

    Energy Technology Data Exchange (ETDEWEB)

    Burch, Ezra A. [Brigham and Women' s Hospital, Department of Radiology, Boston, MA (United States); Orbach, Darren B. [Boston Children' s Hospital, Neurointerventional Radiology, Boston, MA (United States)

    2015-09-15

    Pediatric central nervous system (CNS) vascular anomalies include lesions found only in the pediatric population and also the full gamut of vascular lesions found in adults. Pediatric-specific lesions discussed here include infantile hemangioma, vein of Galen malformation and dural sinus malformation. Some CNS vascular lesions that occur in adults, such as arteriovenous malformation, have somewhat distinct manifestations in children, and those are also discussed. Additionally, children with CNS vascular malformations often have associated broader vascular conditions, e.g., PHACES (posterior fossa anomalies, hemangioma, arterial anomalies, cardiac anomalies, eye anomalies and sternal anomalies), hereditary hemorrhagic telangiectasia, and capillary malformation-arteriovenous malformation syndrome (related to the RASA1 mutation). The treatment of pediatric CNS vascular malformations has greatly benefited from advances in endovascular therapy, including technical advances in adult interventional neuroradiology. Dramatic advances in therapy are expected to stem from increased understanding of the genetics and vascular biology that underlie pediatric CNS vascular malformations. (orig.)

  12. Cosmic-ray tests for quality control of the CDF plug upgrade EM calorimeter and the CDF plug preshower detector

    International Nuclear Information System (INIS)

    The CDF Plug Upgrade electromagnetic (EM) calorimeter and the preshower detector consist of tile-fiber elements forming a projective tower geometry. Each of the 23 longitudinal layers is separated into 24 units in the azimuthal direction. Cosmic-ray tests as a quality control of these mechanically basic units, called the 15 deg. units, were carried out since January 1995 and completed in June 1996. All the units amounting to a total 1200 units were processed. By using HAMAMASU R4125 for the photon readout, the average light yields were measured to be 5.8 and 21 photoelectrons for the EM and the preshower units, respectively. The light yield variation along the longitudinal layers of EM tower was measured to be 10%. A GEANT-simulation study using the results of the cosmic-ray tests was performed for a realistic calorimeter configuration. It was found that the simulated energy resolution was consistent with the requirement of ΔE/E=√(16%)2/E+(1%)2 (E in GeV). Adding preshower response to EM response improved in particular the linearity of the calorimeter. It was possible to achieve the non-linearity of 1% level for energies in the range of 10-200 GeV. (authors)

  13. Experiences from the design and construction of plug II in the Prototype Repository

    Energy Technology Data Exchange (ETDEWEB)

    Dahlstroem, Lars-Olof (NCC Teknik (Sweden))

    2009-12-15

    The intention with this document is to summarise the comprehensive documentation and experience that was gained during the design and construction of the temporary plugs in the Prototype Repository experiment at Aespoe HRL. The Prototype Repository experiment was designed to in full scale test the engineered barriers and their function, including the plug that separate the deposition tunnel from the temporary access- and transportation tunnels that are at atmospheric pressure. This plug is designed and constructed as a concrete plug with a spherical front side and a flat pressurised side. This report presents the processes and operations that were considered when developing the 'plug', design, construction and verification. In the Prototype Repository the demand of leakage control is very high and the maximum length of the plugs is constrained due to available clearance space, experimental set-up and configuration. Therefore a typical 'friction plug' normally used to block waterways in connection with hydropower plants, is not suitable. Instead a plug constructed as an 'arch plug' with abutments was considered. In order to minimize the Excavation Disturbed Zone (EDZ) the abutments, in which the plug is inserted, was excavated by seam drilling with coring technique. The steel formwork was pre-assembled at the ground surface before taken down to the tunnel. The steel was bolted and welded together and crossbars and plywood were mounted on top. Before taken down to the tunnel, the formwork was separated into smaller pieces that were easier to transport down the tunnel but easy to assembly at the Prototype Repository experiment. Before assembling the formwork, a retaining wall was installed to resist the earth and compaction pressure developed from the backfill material. The retaining wall consists of pre-fabricated concrete beams that were installed parallel with the installation of the backfill. Reinforcement was cut and bent at the

  14. Experiences from the design and construction of plug II in the Prototype Repository

    International Nuclear Information System (INIS)

    The intention with this document is to summarise the comprehensive documentation and experience that was gained during the design and construction of the temporary plugs in the Prototype Repository experiment at Aespoe HRL. The Prototype Repository experiment was designed to in full scale test the engineered barriers and their function, including the plug that separate the deposition tunnel from the temporary access- and transportation tunnels that are at atmospheric pressure. This plug is designed and constructed as a concrete plug with a spherical front side and a flat pressurised side. This report presents the processes and operations that were considered when developing the 'plug', design, construction and verification. In the Prototype Repository the demand of leakage control is very high and the maximum length of the plugs is constrained due to available clearance space, experimental set-up and configuration. Therefore a typical 'friction plug' normally used to block waterways in connection with hydropower plants, is not suitable. Instead a plug constructed as an 'arch plug' with abutments was considered. In order to minimize the Excavation Disturbed Zone (EDZ) the abutments, in which the plug is inserted, was excavated by seam drilling with coring technique. The steel formwork was pre-assembled at the ground surface before taken down to the tunnel. The steel was bolted and welded together and crossbars and plywood were mounted on top. Before taken down to the tunnel, the formwork was separated into smaller pieces that were easier to transport down the tunnel but easy to assembly at the Prototype Repository experiment. Before assembling the formwork, a retaining wall was installed to resist the earth and compaction pressure developed from the backfill material. The retaining wall consists of pre-fabricated concrete beams that were installed parallel with the installation of the backfill. Reinforcement was cut and bent at the factory and was ready for

  15. Dealing with vascular conundrums with MR imaging.

    Science.gov (United States)

    Angthong, Wirana; Semelka, Richard C

    2014-07-01

    Magnetic resonance (MR) imaging is a robust imaging modality for evaluation of vascular diseases. Technological advances have made MR imaging widely available for accurate and time-efficient vascular assessment. In this article the clinical usefulness of MR imaging techniques and their application are reviewed, using examples of vascular abnormalities commonly encountered in clinical practice, including abdominal, pelvic, and thoracic vessels. Common pitfalls and problem solving in interpretation of vascular findings in body MR imaging are also discussed. PMID:24889175

  16. MicroRNAs in Vascular Biology

    OpenAIRE

    Munekazu Yamakuchi

    2012-01-01

    Vascular inflammation is an important component of the pathophysiology of cardiovascular diseases, such as hypertension, atherosclerosis, and aneurysms. All vascular cells, including endothelial cells (ECs) and vascular smooth muscle cells (VSMCs), and infiltrating cells, such as macrophages, orchestrate a series of pathological events. Despite dramatic improvements in the treatment of atherosclerosis, the molecular basis of vascular inflammation is not well understood. In the last decade, mi...

  17. Diagnosis advances in vascular cognitive impairment

    Institute of Scientific and Technical Information of China (English)

    Hua Zhou; Zhong Zhao

    2009-01-01

    Vascular cognitive impairment(VCI) encompasses the entire range of cognitive deficits associated with cerebrovascular disease(CVD), from mild deficits with little or no functional impairment, such as vascular cognitive impairment-no dementia(VCIND), to full-blown vascular dementia(VaD). Accurate diagnosis of vascular cognitive impairment is important but may be difficult. In this review we report advances in VCI in the following areas: etiology, subtypes, neuropsychology, biomarkers, neuroimaging, and diagnostic criteria.

  18. Congenital vascular malformations in scintigraphic evaluation

    OpenAIRE

    Pilecki, Stanisław; Gierach, Marcin; Gierach, Joanna; Świętaszczyk, Cyprian; Junik, Roman; Lasek, Władysław

    2014-01-01

    Summary Background Congenital vascular malformations are tumour-like, non-neoplastic lesions caused by disorders of vascular tissue morphogenesis. They are characterised by a normal cell replacement cycle throughout all growth phases and do not undergo spontaneous involution. Here we present a scintigraphic image of familial congenital vascular malformations in two sisters. Material/Methods A 17-years-old young woman with a history of multiple hospitalisations for foci of vascular anomalies a...

  19. Plug-In Hybrid Urban Delivery Truck Technology Demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Miyasato, Matt [South Coast Air Quality Management District Building Corporation, Diamond Bar, CA (United States); Impllitti, Joseph [South Coast Air Quality Management District Building Corporation, Diamond Bar, CA (United States); Pascal, Amar [South Coast Air Quality Management District Building Corporation, Diamond Bar, CA (United States)

    2015-07-31

    The I-710 and CA-60 highways are key transportation corridors in the Southern California region that are heavily used on a daily basis by heavy duty drayage trucks that transport the cargo from the ports to the inland transportation terminals. These terminals, which include store/warehouses, inland-railways, are anywhere from 5 to 50 miles in distance from the ports. The concentrated operation of these drayage vehicles in these corridors has had and will continue to have a significant impact on the air quality in this region whereby significantly impacting the quality of life in the communities surrounding these corridors. To reduce these negative impacts it is critical that zero and near-zero emission technologies be developed and deployed in the region. A potential local market size of up to 46,000 trucks exists in the South Coast Air Basin, based on near- dock drayage trucks and trucks operating on the I-710 freeway. The South Coast Air Quality Management District (SCAQMD), California Air Resources Board (CARB) and Southern California Association of Governments (SCAG) — the agencies responsible for preparing the State Implementation Plan required under the federal Clean Air Act — have stated that to attain federal air quality standards the region will need to transition to broad use of zero and near zero emission energy sources in cars, trucks and other equipment (Southern California Association of Governments et al, 2011). SCAQMD partnered with Volvo Trucks to develop, build and demonstrate a prototype Class 8 heavy-duty plug-in hybrid drayage truck with significantly reduced emissions and fuel use. Volvo’s approach leveraged the group’s global knowledge and experience in designing and deploying electromobility products. The proprietary hybrid driveline selected for this proof of concept was integrated with multiple enhancements to the complete vehicle in order to maximize the emission and energy impact of electrification. A detailed review of all

  20. Kansas Consortium Plug-in Hybrid Medium Duty

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2012-03-31

    On September 30, 2008, the US Department of Energy (DoE), issued a cooperative agreement award, DE-FC26-08NT01914, to the Metropolitan Energy Center (MEC), for a project known as “Kansas Consortium Plug-in Hybrid Medium Duty Certification” project. The cooperative agreement was awarded pursuant to H15915 in reference to H. R. 2764 Congressionally Directed Projects. The original agreement provided funding for The Consortium to implement the established project objectives as follows: (1) to understand the current state of the development of a test protocol for PHEV configurations; (2) to work with industry stakeholders to recommend a medium duty vehicle test protocol; (3) to utilize the Phase 1 Eaton PHEV F550 Chassis or other appropriate PHEV configurations to conduct emissions testing; (4) and to make an industry PHEV certification test protocol recommendation for medium duty trucks. Subsequent amendments to the initial agreement were made, the most significant being a revised Scope of Project Objectives (SOPO) that did not address actual field data since it was not available as originally expected. This project was mated by DOE with a parallel project award given to the South Coast Air Quality Management District (SCAQMD) in California. The SCAQMD project involved designing, building and testing of five medium duty plug-in hybrid electric trucks. SCAQMD had contracted with the Electric Power Research Institute (EPRI) to manage the project. EPRI provided the required match to the federal grant funds to both the SCAQMD project and the Kansas Consortium project. The rational for linking the two projects was that the data derived from the SCAQMD project could be used to validate the protocols developed by the Kansas Consortium team. At the same time, the consortium team would be a useful resource to SCAQMD in designating their test procedures for emissions and operating parameters and determining vehicle mileage. The years between award of the cooperative

  1. Beam plug replacement and alignment under high radiation conditions for cold neutron facilities at Hanaro

    International Nuclear Information System (INIS)

    Full text : The HANARO, an open-tank-in-pool type research reactor of a 30 MWth power in Korea, has been operating for 15 years since its initial criticality in February 1995. The beam port assigned for the cold neutron at HANARO had been used for an 8-m SANS without neutron guides until it was replaced by a cold neutron guide system in 2008. It was developed a cold neutron guide system for the delivery of cold neutrons from the cold neutron source in the reactor to the neutron scattering instruments in the guide hall. Since the HANARO has been operated from 1995, it was a big challenge to replace the existing plug and shutter with the new facilities under high radiation conditions. When the old plug was removed from the beam port in 2008, the radiation level was 230 mSv/hr at the end of beam port. In addition to that, there were more difficult situations such as the poor as-built dimensions of the beam port, limited work space and time constraint due to other constructions in parallel in the reactor hall. Before the removal of the old plug the level of the radiation was measured coming out through a small hole of the plug to estimate the radiation level during the removal of the old plug and installation of a new plug. Based on the measurement and analysis results, special tools and various shielding facilities were developed for the removal of old in-pile plug and the installation of the new in-pile plug assembly safely. In 2008, the old plug and shutter were successfully replaced by the new plug and shutter as shown in this article with a minimum exposure to the workers. A laser tracker system was also one of the main factors in our successful installation and alignment under high radiation conditions and limited work space. The laser tracker was used to measure and align all the mechanical facilities and the neutron guides with a minimum radiation exposure to workers. The alignment of all the guides and accessories were possible during reactor operation because

  2. Near-infraread spectroscopy during peripheral vascular surgery

    DEFF Research Database (Denmark)

    Schroeder, Torben Veith; Eiberg, Jonas Peter; Vogt, Katja; Secher, Niels Henry

    Original,Near-infraread spectroscopy,Vascular disease,Vascular by-pass surgery,Perioperative oxymetry......Original,Near-infraread spectroscopy,Vascular disease,Vascular by-pass surgery,Perioperative oxymetry...

  3. Study on Plug-in Hybrid Electric Vehicle%Plug-in混合动力电动汽车的研究分析

    Institute of Scientific and Technical Information of China (English)

    杨金星; 周荣; 乔维高

    2009-01-01

    外接充电式混合动力电动汽车(Plug-in HEV)是在传统混合动力汽车基础上派生出来的新型节能环保车,可以大大改善汽车有害气体和温室气体排放,提高汽车燃油经济性.文章介绍了Plug-in HEV的动力系统结构,阐述了Plug-in HEV的工作模式及控制策略,指出Plug-in HEV除具有纯电动汽车的全部优点外,还可利用晚间低谷电对电池充电等优点,但同时又受到充电基础设施和成本等因素制约,是一种最有发展前景的混合动力电动汽车.

  4. Apparatus for assembling and welding end plugs to nuclear fuel cladding tubes and inspecting the end plug welds on an automated basis

    International Nuclear Information System (INIS)

    This patent describes an automated apparatus for welding a separate end plug to one open end of each of a succession of nuclear fuel cladding tubes and for inspecting each end plug weld. The apparatus comprising, in combination: a welding station; a cooldown station for cooling each end plug weld in an inert gas atmosphere; a serial number reader station for reading a serial number on each end plug; a first weld inspection station; a second weld inspection station for generating second weld inspection data; a computer system linked with the serial number reader and the first and second weld inspection stations; an input queue for holding a plurality of tubes; a tube transporter for periodically picking individual tubes from the input queque and conveying the tubes in a direction transverse to their tube axis in indexing steps to index positions respectively axially aligned with the welding, serial number reader, and first and second weld inspection stations; and a sorter positioned at an output end of the tube transporter

  5. Identification of molecular processes needed for vascular formation through transcriptome analysis of different vascular systems

    OpenAIRE

    Xu, Peng; Kong, Yimeng; Li, Xuan; Li, Laigeng

    2013-01-01

    Background Vascular system formation has been studied through molecular and genetic approaches in Arabidopsis, a herbaceous dicot that is used as a model system. Different vascular systems have developed in other plants such as crops and trees. Uncovering shared mechanisms underlying vascular development by transcriptome analysis of different vascular systems may help to transfer knowledge acquired from Arabidopsis to other economically important species. Results Conserved vascular genes and ...

  6. Vascularized osseous graft for scaphoid

    International Nuclear Information System (INIS)

    The most commonly used technique for treatment of pseudo-arthrosis of the scaphoid is osteo-synthesis with Kirschnet wires and cortical sponge grafts. Results reported by different teams using this procedure show no more than 90% osseous consolidation, especially in cases where vascularisation of the proximal fragment of the scaphoid is compromised. Here we present a series of ten cases of pseudo-arthrosis of the scaphoid, treated using a new surgical technique involving a vascularized osseous graft of the distal radius. Using this procedure we obtained 100% consolidation, with no complications either during the procedure or immediately post-operatively. Patients returned to work in week 15 on average. In 4 cases we observed discomfort in the area of the scar, which was successfully treated using local cortisone injection. The results obtained are very similar to those seen in the literature on the different techniques for vascularized osseous grafts for pseudo-arthrosis of the scaphoid

  7. Applicability assessment of plug weld to ITER vacuum vessel by crack propagation analysis

    International Nuclear Information System (INIS)

    In order to improve the fabricability of the vacuum vessel (VV) of International Thermonuclear Experimental Reactor (ITER), applicability of plug weld between VV outer shell and stiffening ribs/blanket support housings has been assessed using crack propagation analysis for the plug weld. The ITER VV is a double-wall structure of inner and outer shells with ribs and housings between the shells. For the fabrication of VV, ribs and housings are welded to outer shell after welding to inner shell. A lot of weld grooves should be adjusted for welding outer shell. The plug weld is that outer shells with slit at the weld region are set on ribs/housings then outer shells are welded to them by filling the slits with weld metal. The plug weld can allow larger tolerance of weld groove gap than ordinary butt weld. However, un-welded lengths parallel to outer sell surface remain in the plug weld region. It is necessary to evaluate the allowable un-welded length to apply the plug weld to ITER VV fabrication. For the assessment, the allowable un-welded lengths have been calculated by crack propagation analyses for load conditions, conservatively assuming the un-welded region is a crack. In the analyses, firstly allowable crack lengths are calculated from the stresses of the weld region. Then assuming initial crack length, crack propagation is calculated during operation period. Allowable initial crack lengths are determined on the condition that the propagated cracks should not exceed the allowable crack lengths. The analyses have been carried out for typical inboard straight region and inboard upper curved region with the maximum housing stress. The allowable initial cracks of ribs are estimated to be 8.8mm and 38mm for the rib and the housing, respectively, considering inspection error of 4.4mm. Plug weld between outer shell and ribs/housings could be applicable. (author)

  8. Botulinum neurotoxin type A versus punctal plug insertion in the management of dry eye disease

    Directory of Open Access Journals (Sweden)

    Amal A Bukhari

    2014-01-01

    Full Text Available Purpose: To compare the efficacies of punctal plug insertion and Botulinum toxin injection in dry eye disease not responding to topical medications. Materials and Methods: A non-controlled randomized clinical trial of two parallel groups of 60 dry eye patients seen in the clinic not responding to topical medications were divided into two groups. One group received punctal plugs and the other group received Botulinum toxin injections to prevent lacrimal tear drainage. Results: Of a total of 36 patients with a mean age of 44.5 years who received punctal plugs, 50% of them experienced improvements in the clinical manifestations of their disease. 12/36 (33.3% developed plug extrusion, and 6/36 (16.7% patients developed conjunctival erosions with irritation that necessitated plug removal within one week of insertion. A total of 24 patients with a mean age of 47.5 years received injections of Botulinum toxin. Of these, 83.3% had improvement in all of the clinical manifestations of dry eye. 4/24 (16.7% had no improvement in the degrees to which they experienced foreign body sensations, 33.3% reported shampoo entering the eye while showering. All of the patients who received Botulinum toxin injections were satisfied with the results of their treatment, whereas only 72.3% of the patients who received punctal plugs were satisfied with their results. Conclusion: Botulinum neurotoxin A injections can be a very good alternative to punctal plugs in improving the clinical manifestations of dry eye disease They are associated with the development of fewer and milder complications and with higher levels of patient satisfaction.

  9. Cellular mechanisms during vascular development

    OpenAIRE

    Blum, Yannick

    2012-01-01

    The vascular system is an essential organ in vertebrate animals and provides the organism with enough oxygen and nutrients. It is composed of an interconnected network of blood vessels, which form using a number of different morphogenetic mechanisms. Angiogenesis describes the formation of new blood vessels from preexisting vessels. A number of molecular pathways have been shown to be essential during angiogenesis. However, cellular architecture of blood vessels as well as cellular mechanisms...

  10. Fascia and Primo Vascular System

    OpenAIRE

    Chun Yang; Yi-kuan Du; Jian-bin Wu; Jun Wang; Ping Luan; Qin-lao Yang; Lin Yuan

    2015-01-01

    The anatomical basis for the concept of acupuncture points/meridians in traditional Chinese medicine (TCM) has not been resolved. This paper reviews the fascia research progress and the relationship among acupuncture points/meridians, primo vascular system (PVS), and fascia. Fascia is as a covering, with common origins of layers of the fascial system despite diverse names for individual parts. Fascia assists gliding and fluid flow and holds memory and is highly innervated. Fascia is intimatel...

  11. Quantitative analysis of vascular calcification

    OpenAIRE

    Joh, Jin Hyun; Kim, Dong Ik

    2013-01-01

    Vascular calcification is a prominent feature of atherosclerosis. The mineral composition and quantity within calcified arterial plaques remains unelucidated; therefore, the aim of this study was to analyze the mineral composition of such plaques. Calcified arterial plaques were obtained from patients with abdominal aortic aneurysms (AAAs) and carotid artery stenoses. Calcified aneurysmal plaques were obtained during the routine open repair of AAAs, while calcified carotid plaques were collec...

  12. Vascular instruction of pancreas development

    OpenAIRE

    Cleaver, Ondine; Dor, Yuval

    2012-01-01

    Blood vessels course through organs, providing them with essential nutrient and gaseous exchange. However, the vasculature has also been shown to provide non-nutritional signals that play key roles in the control of organ growth, morphogenesis and homeostasis. Here, we examine a decade of work on the contribution of vascular paracrine signals to developing tissues, with a focus on pancreatic β-cells. During the early stages of embryonic development, blood vessels are required for pancreas spe...

  13. NADPH Oxidases in Vascular Pathology

    OpenAIRE

    Konior, Anna; Schramm, Agata; Czesnikiewicz-Guzik, Marta; Tomasz J. Guzik

    2014-01-01

    Significance: Reactive oxygen species (ROS) play a critical role in vascular disease. While there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases play a central role. They are a source of “kindling radicals,” which affect other enzymes, such as nitric oxide synthase endothelial nitric oxide synthase or xanthine oxidase. This is important, as risk factors for atherosclerosis (hypertension, diabetes, hypercholesterolemia, and smoking) regulate the ...

  14. Tbx1 regulates brain vascularization.

    Science.gov (United States)

    Cioffi, Sara; Martucciello, Stefania; Fulcoli, Filomena Gabriella; Bilio, Marchesa; Ferrentino, Rosa; Nusco, Edoardo; Illingworth, Elizabeth

    2014-01-01

    The transcription factor TBX1 is the major gene involved in 22q11.2 deletion syndrome (22q11.2DS). Using mouse models of these diseases, we have previously shown that TBX1 activates VEGFR3 in endothelial cells (EC), and that this interaction is critical for the development of the lymphatic vasculature. In this study, we show that TBX1 regulates brain angiogenesis. Using loss-of-function genetics and molecular approaches, we show that TBX1 regulates the VEGFR3 and DLL4 genes in brain ECs. In mice, loss of TBX1 causes global brain vascular defects, comprising brain vessel hyperplasia, enhanced angiogenic sprouting and vessel network disorganization. This phenotype is recapitulated in EC-specific Tbx1 conditional mutants and in an EC-only 3-dimensional cell culture system (matrigel), indicating that the brain vascular phenotype is cell autonomous. Furthermore, EC-specific conditional Tbx1 mutants have poorly perfused brain vessels and brain hypoxia, indicating that the expanded vascular network is functionally impaired. In EC-matrigel cultures, a Notch1 agonist is able to partially rescue microtubule hyperbranching induced by TBX1 knockdown. Thus, we have identified a novel transcriptional regulator of angiogenesis that exerts its effect in brain by negatively regulating angiogenesis through the DLL4/Notch1-VEGFR3 regulatory axis. Given the similarity of the phenotypic consequences of TBX1 mutation in humans and mice, this unexpected role of TBX1 in murine brain vascularization should stimulate clinicians to search for brain microvascular anomalies in 22q11.2DS patients and to evaluate whether some of the anatomical and functional brain anomalies in patients may have a microvascular origin. PMID:23945394

  15. Cocaine-related vascular headaches.

    OpenAIRE

    Dhuna, A; Pascual-Leone, A; Belgrade, M

    1991-01-01

    The records of 21 patients admitted to hospital from January 1985 to December 1988 for acute headache associated with cocaine intoxication were reviewed. Fifteen patients were identified who experienced headaches with migrainous features in the absence of neurological or systemic complications. None of them had a history of cocaine-unrelated headaches or a family history of migraine, and all had a favourable outcome. Three possible mechanisms of cocaine-related vascular headaches are discusse...

  16. Hydrogen sulfide and vascular relaxation

    Institute of Scientific and Technical Information of China (English)

    SUN Yan; TANG Chao-shu; DU Jun-bao; JIN Hong-fang

    2011-01-01

    Objective To review the vasorelaxant effects of hydrogen sulfide (H2S) in arterial rings in the cardiovascular system under both physiological and pathophysiological conditions and the possible mechanisms involved.Data sources The data in this review were obtained from Medline and Pubmed sources from 1997 to 2011 using the search terms "hydrogen sulfide" and ""vascular relaxation".Study selection Articles describing the role of hydrogen sulfide in the regulation of vascular activity and its vasorelaxant effects were selected.Results H2S plays an important role in the regulation of cardiovascular tone.The vasomodulatory effects of H2S depend on factors including concentration,species and tissue type.The H2S donor,sodium hydrosulfide (NarS),causes vasorelaxation of rat isolated aortic rings in a dose-dependent manner.This effect was more pronounced than that observed in pulmonary arterial rings.The expression of KATP channel proteins and mRNA in the aortic rings was increased compared with pulmonary artery rings.H2S is involved in the pathogenesis of a variety of cardiovascular diseases.Downregulation of the endogenous H2S pathway is an important factor in the pathogenesis of cardiovascular diseases.The vasorelaxant effects of H2S have been shown to be mediated by activation of KATP channels in vascular smooth muscle cells and via the induction of acidification due to activation of the CI/HCO3 exchanger.It is speculated that the mechanisms underlying the vasoconstrictive function of H2S in the aortic rings involves decreased NO production and inhibition of cAMP accumulation.Conclusion H2S is an important endogenous gasotransmitter in the cardiovascular system and acts as a modulator of vascular tone in the homeostatic regulation of blood pressure.

  17. Vascular parameters from angiographic images

    International Nuclear Information System (INIS)

    This paper measures geometric and dynamic vascular parameters using digital angiographic image sequences: An image analysis system for neuroangiography is being developed by the Medical Imaging Division and Endovascular Therapy section of our department. Angiographic images are obtained from a GE Digital Fluoricon 5000 system. The image sets are analyzed on a Stellar GS2000 graphics mini-supercomputer using software modules written for use with the Application Visualization System (AVS). Flow phantoms are used to evaluate analysis routines and bolus injection techniques

  18. Vascular gene expression: a hypothesis

    OpenAIRE

    Martínez-Navarro, Angélica C.; Galván-Gordillo, Santiago V.; Xoconostle-Cázares, Beatriz; Ruiz-Medrano, Roberto

    2013-01-01

    The phloem is the conduit through which photoassimilates are distributed from autotrophic to heterotrophic tissues and is involved in the distribution of signaling molecules that coordinate plant growth and responses to the environment. Phloem function depends on the coordinate expression of a large array of genes. We have previously identified conserved motifs in upstream regions of the Arabidopsis genes, encoding the homologs of pumpkin phloem sap mRNAs, displaying expression in vascular ti...

  19. Endangered vascular plants in Japan

    OpenAIRE

    IWATSUKI, Kunio

    2008-01-01

    The history of the Red List of Japanese vascular plants is briefly reviewed for editing and research. Especially on the results of recent monitoring, the present status of information and conservation activities on the endangered plants in Japan is discussed and the dynamics of the Japanese flora are taken up, in relation to basic research on plant biodiversity on the Japanese Archipelago. The figures of endangered plants are not very variable during the past quarter of a century, but we can ...

  20. Radiology of peripheral vascular diseases

    International Nuclear Information System (INIS)

    This volume provides a comprehensive account of the use of modern imaging procedures for the diagnosis of arterial and venous diseases. Each imaging modality is separately considered and applications in individual diseases are then explained with the aid of excellent illustrations. In addition, vascular interventions such as balloon angioplasty, local thrombolysis, and stent implantation are discussed and appraised. Special attention is devoted to the problem of radiation burden for patients. The authors are all recognized experts in angiology, phlebology, and interventional radiology. (orig.)

  1. Vascular Complications of Cancer Chemotherapy.

    Science.gov (United States)

    Cameron, Alan C; Touyz, Rhian M; Lang, Ninian N

    2016-07-01

    Development of new anticancer drugs has resulted in improved mortality rates and 5-year survival rates in patients with cancer. However, many of the modern chemotherapies are associated with cardiovascular toxicities that increase cardiovascular risk in cancer patients, including hypertension, thrombosis, heart failure, cardiomyopathy, and arrhythmias. These limitations restrict treatment options and might negatively affect the management of cancer. The cardiotoxic effects of older chemotherapeutic drugs such as alkylating agents, antimetabolites, and anticancer antibiotics have been known for a while. The newer agents, such as the antiangiogenic drugs that inhibit vascular endothelial growth factor signalling are also associated with cardiovascular pathology, especially hypertension, thromboembolism, myocardial infarction, and proteinuria. Exact mechanisms by which vascular endothelial growth factor inhibitors cause these complications are unclear but impaired endothelial function, vascular and renal damage, oxidative stress, and thrombosis might be important. With increasing use of modern chemotherapies and prolonged survival of cancer patients, the incidence of cardiovascular disease in this patient population will continue to increase. Accordingly, careful assessment and management of cardiovascular risk factors in cancer patients by oncologists and cardiologists working together is essential for optimal care so that prolonged cancer survival is not at the expense of increased cardiovascular events. PMID:26968393

  2. [Vascular Ehlers-Danlos syndrome].

    Science.gov (United States)

    Frank, Michael

    2009-04-20

    Vascular type Ehlers-Danlos syndrome (EDS) is a rare inherited disease with an autosomal dominant trait. The mutation of the COL3A1 gene which encodes type III collagen, is responsible of early vascular (spontaneous arterial rupture or dissection), digestive (perforation) and obstetrical events (uterine and arterial rupture). Diagnosis of the disease is primarily clinical, especially in case of characteristic morphologic features. Diagnostic certainty is obtained by evidencing the mutation of the COL3A1 gene. Some arterial lesions are suggestive of the disease, as dissecting aneurysms of the internal carotid, of the iliac arteries, and of the anterior visceral aortic branches, fusiform aneurisms of the splenic artery, and the occurrence of a non traumatic direct carotid-cavernous fistula. The occurrence of a spontaneous peritonitis or of an extensive perineal tear after delivery should also draw physician's attention. Because of the unpredictability of arterial or organ rupture, any patient diagnosed with vascular type EDS presenting with an acute pain syndrome should be considered as a trauma situation and be investigated straightaway by CT-scan or MRI testing, in order to eliminate a life threatening complication. PMID:19462862

  3. Flow plug with length-to-hole size uniformity for use in flow conditioning and flow metering

    Science.gov (United States)

    England, John Dwight (Inventor); Kelley, Anthony R. (Inventor)

    2012-01-01

    A flow plug of varying thickness has a plurality of holes formed therethrough. The plug fits in a conduit such that a fluid flow in the conduit passes through the plug's holes. Each hole is defined by a parameter indicative of size in terms of the cross-sectional area thereof. A ratio of hole length-to-parameter is approximately the same for all of the holes.

  4. Changing demographics in patients with vascular disease.

    Science.gov (United States)

    Kwolek, Christopher J; Clagett, G Patrick

    2009-02-01

    The United States population with vascular disease has changed dramatically during the past 2 decades, with large increases in the proportion of Hispanic, African American, and other minority patients. Not only has the number of these patients increased, but the types and distribution of vascular disease in minority populations is also different from that encountered in non-Hispanic whites. Although genetic makeup accounts for some of these differences, access to vascular care is also an important determinant, with many minority patients presenting late in the course of the disease process. These factors create significant challenges for the vascular specialists caring for these patients. The vascular surgery workforce is composed of >90% white men and does not currently represent the changes in the population of patients with vascular disease. In addition, women with vascular disease comprise up to 50% of many vascular surgery practices. In many parts of the country, Hispanics and African Americans outnumber non-Hispanic whites with vascular disease. Yet, women and minority physicians are still significantly under-represented in the field of vascular surgery. This year's E. Stanley Crawford Critical Issues Forum at the Society for Vascular Surgery meeting addressed the disconnect between the vascular surgery workforce and the patients whom we serve. This article reviews the projected demographic changes in the population of the United States, which supports the need for training a vascular surgery workforce that is more diverse. This article also reviews the current status of minority and female representation in medical schools, surgical training programs, and vascular surgery programs in the United States. PMID:19216973

  5. Plugs for deposition tunnels in a deep geologic repository in granitic rock. Concepts and experience

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, D.A. (AECL, Chalk River (Canada)); Boergesson, L. (Clay Technology, Lund (Sweden)); Gunnarsson, D. (Swedish Nuclear Fuel and Waste Management Co, Stockholm (Sweden)); Hansen, J. (Posiva Oy, Eurajoki (Finland))

    2009-11-15

    Regardless of the emplacement geometry selected in a geological repository for spent nuclear fuel, there will be a requirement for the access tunnels to remain open while repository operations are ongoing. The period of repository operation will stretch for many years (decades to more than a century depending on disposal concept and number of canisters to be installed). Requirements for extended monitoring of the repository before final closure may further extend the period over which the tunnels must remain open. The intersection of the emplacement rooms/drifts and the access tunnels needs to be physically closed in order to ensure that the canisters remain undisturbed and that no undesirable hydraulic conditions are allowed to develop within the backfilled volume. As a result of these requirements, generic guidelines and design concepts have been developed for 'Plugs' that are intended to provide mechanical restraint, physical security and hydraulic control functions over the short-term (repository operational and pre-closure monitoring periods). This report focuses on the role and requirements of plugs to be installed at emplacement room/ tunnel/drift entrances or in other locations within the repository that may require installation of temporary mechanical or hydraulic control structures. These plugs are not necessarily a permanent feature of the repository and may, if required, be removed for later installation of a permanent seal. Room/Drift plugs are also by their defined function, physically accessible during repository operation so their performance can be monitored and remedial actions taken if necessary (e.g. increased seepage past the plug). A considerable number of sealing demonstrations have been undertaken at several research laboratories that are focussed on development of technologies and materials for use in isolation of spent nuclear fuel and these are briefly reviewed in this report. Additionally, technologies developed for non

  6. Prediction of Plug Tip Position in Rotary Tube Piercing Mill Using Simulation and Experiment

    Science.gov (United States)

    Lee, Hyoung Wook; Lee, Geun An; Kim, Eung Zu; Choi, Seogou

    Typical seamless tube production processes are an extrusion and a rotary tube piercing. The rotary piercing process is more competitive than the extrusion process from the viewpoint of flexibility. Main components of this equipment are twin rolling mills and a plug. Twin rolling mills are installed on a skew with proper angles in two directions. These angles are called the cross angle and the feed angle. The internal crack initiation and the growth at central area of the billet are gradually progressed due to the Mannesmann effects. The feed angle affects on the position of the crack initiation in the rotary tube piercing process. Adjustable design parameters in the equipment are the feed angle and the plug insertion depth. In this research, the rotary tube piercing equipment was developed. Finite element analyses with the plug and without the plug were carried out in order to predict the internal crack initiation position under good calculation efficiency. Ductile fracture models with the one variable equation were utilized to crack initiation criteria. The forward distance of the plug was determined to be 5 mm through the analysis. It was testified by experiments of a carbon steel billet.

  7. Design, production and initial state of the backfill and plug in deposition tunnels

    International Nuclear Information System (INIS)

    The report is included in a set of Production reports, presenting how the KBS-3 repository is designed, produced and inspected. The set of reports is included in the safety report for the KBS-3 repository and repository facility. The report provides input on the initial state of the backfill and plug in deposition tunnels for the assessment of the long-term safety, SR-Site. The initial state refers to the properties of the engineered barriers once they have been finally placed in the KBS-3 repository and will not be further handled within the repository facility. In addition, the report provides input to the operational safety report, SR-Operation, on how the backfill and plug shall be handled and installed. The report presents the design premises and reference designs of the backfill and plug in deposition tunnels and verifies their conformity to the design premises. It also describes the production of the backfill from excavation and delivery of backfill material to installation in the deposition tunnel, and gives an outline of the installation of the plug. Finally, the initial states of the backfill and plug and their conformity to the reference designs and design premises are presented

  8. Numerical Simulations of the Propagation of a Liquid Plug through a 2D Airway Bifurcation

    Science.gov (United States)

    Vaughan, Benjamin L., Jr.; Grotberg, James B.

    2010-11-01

    Numerous medical therapies require the instillation of liquids plugs and their delivery throughout the pulmonary airways. This process and the effect on the resulting liquid distribution is controlled by a number of parameters, including airway orientation with respect to gravity, initial plug volume, liquid physical properties, and the imposed airflow rate which drives the plug from behind. The airflow rate defines an operative Capillary number, Ca, and the influence of gravity appears as an effective Bond number, Bo, whose magnitude varies with orientation. In this study, we develop a numerical method for solving the propagation of a liquid plug into a two-dimensional airway bifurcation consisting of a parent channel branching into two daughter channels. We measure the splitting ratio, RS, which is defined as the ratio of the liquid plug volumes between the daughter branches. RS increases with Ca and asymptotes to 1 as Ca goes to infinity, which corresponds to an equal split, while increasing Bo requires a higher value of Ca for an equal split. We also examine the normal and shear stresses on the bifurcation walls and observe that the stresses on the upper walls increase as Bo increases while the stresses on the lower walls decrease as Bo increases.

  9. Real Time Computer for Plugging Indicator Control of Prototype Fast Breeder Reactor

    International Nuclear Information System (INIS)

    Prototype Fast Breeder Reactor (PFBR) is in the advanced stage of construction at Kalpakkam, India. Liquid sodium is used as coolant to transfer the heat produced in the reactor core to steam water circuit. Impurities present in the sodium are removed using purification circuit. Plugging indicator is a device used to measure the purity of the sodium. Versa Module Europa bus based Real Time Computer (RTC) system is used for plugging indicator control. Hot standby architecture consisting of dual redundant RTC system with switch over logic system is the configuration adopted to achieve fault tolerance. Plugging indicator can be controlled in two modes namely continuous and discontinuous mode. Software based Proportional-Integral-Derivative (PID) algorithms are developed for plugging indicator control wherein the set point changes dynamically for every scan interval of the RTC system. Set points and PID constants are kept as configurable in runtime in order to control the process in very efficient manner, which calls for reliable communication between RTC system and control station, hence TCP/IP protocol is adopted. Performance of the RTC system for plugging indicator control was thoroughly studied in the laboratory by simulating the inputs and monitored the control outputs. The control outputs were also monitored for different PID constants. Continuous and discontinuous mode plots were generated. (authors)

  10. Effect of beam channel plugging on the outcome of gamma knife radiosurgery for trigeminal neuralgia

    International Nuclear Information System (INIS)

    Purpose: We studied the influence of using plugs for brainstem protection during gamma knife radiosurgery (GKR) of trigeminal neuralgia (TN), with special emphasis on irradiation doses delivered to the trigeminal nerve, pain outcomes, and incidence of trigeminal dysfunction. Methods and Materials: A GKR procedure for TN using an anterior cisternal target and a maximum dose of 90 Gy was performed in 109 patients. For 49 patients, customized beam channel blocking (plugs) were used to reduce the dose delivered to the brainstem. We measured the mean and integrated radiation doses delivered to the trigeminal nerve and the clinical course of patients treated with and without plugs. Results: We found that blocking increases the length of trigeminal nerve exposed to high-dose radiation, resulting in a significantly higher mean dose to the trigeminal nerve. Significantly more of the patients with blocking achieved excellent pain outcomes (84% vs. 62%), but with higher incidences of moderate and bothersome trigeminal nerve dysfunction (37% mild/10% bothersome with plugs vs. 30% mild/2% bothersome without). Conclusions: The use of plugs to protect the brainstem during GKR treatment for TN increases the dose of irradiation delivered to the intracisternal trigeminal nerve root and is associated with an important increase in the incidence of trigeminal nerve dysfunction. Therefore, beam channel blocking should be avoided for 90 Gy-GKR of TN

  11. Damage Tolerance Assessment of Friction Pull Plug Welds in an Aluminum Alloy

    Science.gov (United States)

    McGill, Preston; Burkholder, Jonathan

    2012-01-01

    Friction stir welding is a solid state welding process used in the fabrication of cryogenic propellant tanks. Self-reacting friction stir welding is one variation of the friction stir weld process being developed for manufacturing tanks. Friction pull plug welding is used to seal the exit hole that remains in a circumferential self-reacting friction stir weld. A friction plug weld placed in a self-reacting friction stir weld results in a non-homogenous weld joint where the initial weld, plug weld, their respective heat affected zones and the base metal all interact. The welded joint is a composite plastically deformed material system with a complex residual stress field. In order to address damage tolerance concerns associated with friction plug welds in safety critical structures, such as propellant tanks, nondestructive inspection and proof testing may be required to screen hardware for mission critical defects. The efficacy of the nondestructive evaluation or the proof test is based on an assessment of the critical flaw size. Test data relating residual strength capability to flaw size in an aluminum alloy friction plug weld will be presented.

  12. Design, production and initial state of the backfill and plug in deposition tunnels

    Energy Technology Data Exchange (ETDEWEB)

    Boerjesson, Lennart; Gunnarsson, David; Johannesson, Lars-Erik; Jonsson, Esther

    2010-12-15

    The report is included in a set of Production reports, presenting how the KBS-3 repository is designed, produced and inspected. The set of reports is included in the safety report for the KBS-3 repository and repository facility. The report provides input on the initial state of the backfill and plug in deposition tunnels for the assessment of the long-term safety, SR-Site. The initial state refers to the properties of the engineered barriers once they have been finally placed in the KBS-3 repository and will not be further handled within the repository facility. In addition, the report provides input to the operational safety report, SR-Operation, on how the backfill and plug shall be handled and installed. The report presents the design premises and reference designs of the backfill and plug in deposition tunnels and verifies their conformity to the design premises. It also describes the production of the backfill from excavation and delivery of backfill material to installation in the deposition tunnel, and gives an outline of the installation of the plug. Finally, the initial states of the backfill and plug and their conformity to the reference designs and design premises are presented

  13. Experimental and numerical testing of an innovative steam generator tube plugging procedure

    International Nuclear Information System (INIS)

    Highlights: • We used Ansys code to study the plastic deformation of the plug during the electro-hydraulic shock. • The Johnson–Cook plasticity model was employed to study the material elastic–plastic dynamics. • The numerical results obtained were compared against experimental data. • The results showed that the input parameters uncertainties influence the plug installation. - Abstract: This paper presents the development of a finite element model used to numerically investigate the behaviour of an innovative defective tube isolation device. The high-speed plastic deformation by electro-hydraulic shock was proposed for plug installing in a steam generator tube simulator. The objective of the study was to evaluate the influence of the geometrical, material and hydraulic shock parameters upon the performance of the plugging procedure using an advanced 3-dimensional simulation model created in LS-DYNA general code. The computational model employs the Johnson–Cook plasticity model for SS321 to study the high strain rate, elastic–plastic dynamics of the process. The results of the simulations compared against experimental data have shown the great influence of the model parameters uncertainties on the success of the plug installation

  14. Cell-based strategies for vascular regeneration.

    Science.gov (United States)

    Zou, Tongqiang; Fan, Jiabing; Fartash, Armita; Liu, Haifeng; Fan, Yubo

    2016-05-01

    Vascular regeneration is known to play an essential role in the repair of injured tissues mainly through accelerating the repair of vascular injury caused by vascular diseases, as well as the recovery of ischemic tissues. However, the clinical vascular regeneration is still challenging. Cell-based therapy is thought to be a promising strategy for vascular regeneration, since various cells have been identified to exert important influences on the process of vascular regeneration such as the enhanced endothelium formation on the surface of vascular grafts, and the induction of vessel-like network formation in the ischemic tissues. Here are a vast number of diverse cell-based strategies that have been extensively studied in vascular regeneration. These strategies can be further classified into three main categories, including cell transplantation, construction of tissue-engineered grafts, and surface modification of scaffolds. Cells used in these strategies mainly refer to terminally differentiated vascular cells, pluripotent stem cells, multipotent stem cells, and unipotent stem cells. The aim of this review is to summarize the reported research advances on the application of various cells for vascular regeneration, yielding insights into future clinical treatment for injured tissue/organ. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 1297-1314, 2016. PMID:26864677

  15. Porous apatite-wollastonite glass-ceramic as an intramedullary plug.

    Science.gov (United States)

    Fujita, H; Iida, H; Ido, K; Matsuda, Y; Oka, M; Nakamura, T

    2000-05-01

    We evaluated the efficacy and biocompatibility of porous apatite-wollastonite glass ceramic (AW-GC) as an intramedullary plug in total hip replacement (THR) for up to two years in 22 adult beagle dogs. Cylindrical porous AW-GC rods (70% porosity, mean pore size 200 microm) were prepared. Four dogs were killed at 1, 3, 6 and 12 months each and six at 24 months after implantation. Radiological evaluation confirmed the efficacy of porous AW-CG as an intramedullary plug. Histological evaluation showed osteoconduction at one month and resorption of the porous AW-GC, which was replaced by newly-formed bone, at 24 months. Our findings indicate that porous AW-GC can be used clinically as an intramedullary plug in THR. PMID:10855893

  16. Structural Integrity Evaluation of Rotating Plug in a Steady State Condition

    Energy Technology Data Exchange (ETDEWEB)

    Han, In-su; Koo, Gyeong-Hoi; Kim, Sung-Kyun; Kim, Jong-Bum [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    Its basic structure is much the same as that of stationary portion of the reactor head. The RP is has many penetration holes for control rod drive mechanism (CRDM), the in vessel transfer machine(IVTM) an in-service inspection (ISI) instruments. In this study, the steady state analysis for the rotating plug was performed and the structural integrity was assessed in accordance with ASME Section III, Division 5 HB. In this paper, the structural integrities of the rotating plug under the design condition and service level A condition have been assessed according to ASME code. As a result, it was confirmed that the structural integrity of the rotating plug was secured for a steady state condition. For the future work, a transient analysis and a seismic analysis need to be performed by combining the different design loads.

  17. Real time computer based control system for rotatable plugs of PFBR

    International Nuclear Information System (INIS)

    A 500 MWe Prototype Fast Breeder Reactor (PFBR) is being constructed at Kalpakkam, Tamilnadu. Two Rotatable Plugs (RP) known as Small Rotatable Plug (SRP) and Large Rotatable Plug (LRP) are provided on the top shield of PFBR to allow access to any position on the grid plate for handling core subassemblies using Transfer Arm (TA). The Real Time Computers (RTC) systems are deployed to rotate the RP remotely in either clockwise or counter-clockwise direction from Handling Control Room (HCR) Concole-1, HCR Panel-1 and Reactor Containment Building Local Control Centre-3 (RCBLCC-3) display station with the positioning accuracy of +/- 1.27 arcmin for SRP and +/- 0.196 arcmin for LRP. (author)

  18. Assessment of Welding System Modification of The Candu and PWR Fuel Element Types end Plug

    International Nuclear Information System (INIS)

    To anticipate future possibility of a nuclear fuel element industry in Indonesia, research on other types of nuclear fuel element beside Cirene type has to be done. It can be accomplished, one of them, by modifying the already available equipment. Based on the sheath material, the sheath dimension and the welding process parameters such as welding current and welding cycles, the available Magnetic Force Welding can be used for welding end plug of Candu nuclear fuel element by modifying some of its components (tube clamp, plug clamp, etc). The available Pellet drying and element filling furnace with its supporting system with includes helium gas filling, welding chamber, argon gas supply, vacuum system, sheath clamp and sheath driving system can be used for welding end plug with sheath of PWR nuclear fuel element by adding og Tungsten inert Gas (TIG) welding machine in the welding chamber and modifying a few components (seal clamp, sheath clamp)

  19. Experimental investigation of gas hydrate formation, plugging and transportability in partially dispersed and water continuous systems

    Science.gov (United States)

    Vijayamohan, Prithvi

    As oil/gas subsea fields mature, the amount of water produced increases significantly due to the production methods employed to enhance the recovery of oil. This is true especially in the case of oil reservoirs. This increase in the water hold up increases the risk of hydrate plug formation in the pipelines, thereby resulting in higher inhibition cost strategies. A major industry concern is to reduce the severe safety risks associated with hydrate plug formation, and significantly extending subsea tieback distances by providing a cost effective flow assurance management/safety tool for mature fields. Developing fundamental understanding of the key mechanistic steps towards hydrate plug formation for different multiphase flow conditions is a key challenge to the flow assurance community. Such understanding can ultimately provide new insight and hydrate management guidelines to diminish the safety risks due to hydrate formation and accumulation in deepwater flowlines and facilities. The transportability of hydrates in pipelines is a function of the operating parameters, such as temperature, pressure, fluid mixture velocity, liquid loading, and fluid system characteristics. Specifically, the hydrate formation rate and plugging onset characteristics can be significantly different for water continuous, oil continuous, and partially dispersed systems. The latter is defined as a system containing oil/gas/water, where the water is present both as a free phase and partially dispersed in the oil phase (i.e., entrained water in the oil). Since hydrate formation from oil dispersed in water systems and partially dispersed water systems is an area which is poorly understood, this thesis aims to address some key questions in these systems. Selected experiments have been performed at the University of Tulsa flowloop to study the hydrate formation and plugging characteristics for the partially dispersed water/oil/gas systems as well as systems where the oil is completely dispersed

  20. Numerical Analysis of Soil Plug Inside Suction Foundations During Suction Penetration by Discrete Element Method

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The phenomenon of the soil plug usually rising inside the suction foundations during suction penetration was quantitatively described and predicted. The formation process of the soil plug was simulated and calculated by DEM (discrete element method) model. The seepage flow, the self-weight of soil, the friction on the chamber wall as well as the suction inside the chamber are considered as the main external forces in the process. The results are compared with a set of laboratory model tests performed by using three soil types (sand, silty clay and clay) in the Bohai Sea area. The heights of soil plug from numerical estimations are lower than those from model test results, mainly because the suction pressure and friction resistance are applied in an ideal way under the numerical simulation.

  1. Structural Integrity Evaluation of Rotating Plug in a Steady State Condition

    International Nuclear Information System (INIS)

    Its basic structure is much the same as that of stationary portion of the reactor head. The RP is has many penetration holes for control rod drive mechanism (CRDM), the in vessel transfer machine(IVTM) an in-service inspection (ISI) instruments. In this study, the steady state analysis for the rotating plug was performed and the structural integrity was assessed in accordance with ASME Section III, Division 5 HB. In this paper, the structural integrities of the rotating plug under the design condition and service level A condition have been assessed according to ASME code. As a result, it was confirmed that the structural integrity of the rotating plug was secured for a steady state condition. For the future work, a transient analysis and a seismic analysis need to be performed by combining the different design loads

  2. Mobotware – A Plug-in Based Framework For Mobile Robots

    DEFF Research Database (Denmark)

    Beck, Anders Billesø; Andersen, Nils Axel; Andersen, Jens Christian;

    2010-01-01

    integration of sensors, fast porting to new robots and core system stability and maintainability in an undisciplined programming environment. Real-time performance is assured by using RTAI-Linux; core stability is obtained by using plug-ins for user developed modules. The plug-in based module structure......This paper describes a plug-in based software framework developed at Automation and Control, DTU Electrical Engineering. The software has been used for education and research in mobile robotics for the last decade. Important design criteria have been real-time performance of the control level, easy...... enabled many application i.e. robust navigation in an orchard with an autonomous tractor (Andersen,2010). Furthermore by providing a simple scripting robot control language the system also supports use by non-technicians....

  3. An unusual case of salt plugging in a high-pressure sour gas well

    Energy Technology Data Exchange (ETDEWEB)

    Place, M.C.; Smith, J.T.

    1984-09-01

    In this paper the authors develop an understanding of the plugging problem by presenting material on two wells: the Shell Ridgeway 1-R well in the Southwest Pineywoods Field, and the Shell Burch number1 well in the Thomasville Field. These two wells have pay zones of similar quality and are located in similar positions relative to the gas water contacts in their respective fields. The following items are discussed: Characteristics of the pay intervals, reservoir conditions and structural settings for the two wells; completion and production histories for the two wells; the solubility of NaCl in sour gas based on the work of Dr. Hyne and the implications of these data for the plugging problems; chemical evidence to support the hypothesis that NaCl deposition occurs from brine flowing into the Shell Ridgeway 1-R well; a suggested prognosis of the sequence of events during a plugging and treatment cycle of the Shell Ridgeway 1-R well.

  4. Clinical pharmacology and vascular risk.

    Science.gov (United States)

    Silvestrelli, G; Corea, F; Micheli, S; Lanari, A

    2010-01-01

    Pharmacological treatment and several drugs of abuse have been associated with ischemic heart disease (IHD) and cerebrovascular diseases (CVD). However, there is a paucity of data on the independent risk of vascular disease (VD) associated with pharmacological treatment and no controlled trials demonstrating a reduction in risk with abstinence. Information about IHD and CVD-related drug abuse is mainly limited to epidemiological studies focused on urban populations. The potential link between some pharmacological treatments (estrogen, some oncologic drugs and some atypical antipsychotics) and cerebrovascular adverse events was analyzed, but disagreement about an association persists. Drugs of abuse, including cocaine, amphetamines and heroin, have been associated with an increased vascular risk. These drugs can cause abrupt changes in blood pressure, vasculitic-type changes, lead to embolization caused by infective endocarditis, and hemostatic and hematologic abnormalities that can result in increased blood viscosity and platelet aggregation. Long-term treatment strategies based on medication, psychological support, and outreach programs play an important role in treatment of drug dependency. In these last years public interest in risk factors for VD has been constantly increasing and the successful identification and management of pharmacological treatment and drug abuse can be challenging. One of the major public health issues for the future will be to focus more on new vascular risk factor recognition and management. The objective of this chapter is to review the relevance of IHD and CVD associated with various pharmacological treatments and drug abuse with focusing on ischemic disease. This chapter reports the clinical evidence of this association and analyzes the experimental role of new drugs as a growing risk factor of VD with the hypothetical new association. In conclusion, in this chapter great attention is paid to evaluating the scientific and real

  5. Spinal vascular malformations; Spinale Gefaessmalformationen

    Energy Technology Data Exchange (ETDEWEB)

    Yilmaz, U. [Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg/Saar (Germany)

    2012-05-15

    Spinal vascular malformations are a group of rare diseases with different clinical presentations ranging from incidental asymptomatic findings to progressive tetraplegia. This article provides an overview about imaging features as well as clinical and therapeutic aspects of spinal arteriovenous malformations, cavernomas and capillary telangiectasia. (orig.) [German] Spinale Gefaessmalformationen sind eine Gruppe seltener Erkrankungen mit unterschiedlichen klinischen Praesentationen, die vom asymptomatischen Zufallsbefund bis zur progredienten Tetraparese reichen. Dieser Artikel gibt einen Ueberblick ueber radiologische Befunde sowie klinische und therapeutische Aspekte von spinalen arteriovenoesen Malformationen, Kavernomen und kapillaeren Teleangiektasien. (orig.)

  6. Ghrelin does not modulate angiogenesis in matrigel plug in normal and diet-induced obese mice

    Directory of Open Access Journals (Sweden)

    Zoya Tahergorabi

    2013-01-01

    Full Text Available Background: The reciprocal interaction between adipocytes and angiogenesis is considered as an essential component in the development and expansion of adipose tissue. The aim of this study was to evaluate the effect of ghrelin on angiogenic response using in vivo angiogenesis assay of matrigel plug and its correlation with serum leptin levels in normal and diet-induced obese mice. Materials and Methods: This experimental study has been done on 24 male C57BL/6 mice which were randomly divided into four groups: Normal diet (ND or control, ND + ghrelin, high-fat-diet (HFD or obese and HFD + ghrelin (n = 6/group. Obese and control groups received HFD or standard diet for 14 weeks. Then, growth factor reduced matrigel plug (500 ΅l containing bFGF (basic fibroblast growth factor; 100 ng with or without ghrelin (100 ΅g/kg was injected subcutaneously in the mid-ventral abdominal region of each mice. After 10 days, blood samples were taken and matrigel plugs were removed under anesthesia and angiogenic response was assessed by immunohisochemical staining. Results: HFD significantly increased angiogenesis in matrigel plug as expressed as the number of CD31-positive cells than standard diet (43 ΁ 5 vs. 13 ΁ 2.5 CD31 + cells/field. Ghrelin did not alter angiogenesis in matrigel plug in both obese and control groups. There was a strong positive correlation between the number of CD31-positive cells and serum leptin concentration (r = 0.91. Conclusion: Leptin as an angiogenic factor has a positive correlation with angiogenesis in matrigel plug model of angiogenesis and ghrelin could not alter angiogenesis.

  7. Tube Plugging Criteria for the High-pressure Heaters of Ulchin NPP 3 and 4

    International Nuclear Information System (INIS)

    Power generation field urges nuclear power plants to reduce operating and maintaining costs to remain competitive. To reduce the cost by means of preventing the lowering thermal efficiency, the inspection of balance-of-plant heat exchanger, which was treated as not important work, becomes important. The tubing materials and tube thickness of heat exchangers in nuclear power plants are selected to withstand system temperature, pressure, and corrosion. But tubes have experienced leaks and failures and plugged based upon eddy current testing (ET) results. There are some problems for plugging the heat exchanger tubes since the criterion and its basis are not clearly described. For this reason, the criteria for the tube wall thickness are addressed in order to operate the heat exchangers in nuclear power plant without trouble during the cycle. The feed water heater is a kind of heat exchanger which raises the temperature of water supplied from the condenser. The heat source of high-pressure heaters is the extraction steam from the high-pressure turbine and moisture separator re-heater. If the tube wall of the heater is broken, the feed water flowing inside the tube intrudes to shell side. This forces the turbine to be stop in order to protect it. There are many codes and standards to be referred for calculating the minimum thickness of the heat exchanger tube in the designing stage. However, the codes and standards related to show the tube plugging criteria may not exist currently. In this paper, a method to establish the tube plugging criteria of BOP heat exchangers is introduced and the tube plugging criteria for the high pressure heaters of Ulchin NPP No. 3 and 4. This method relies on the similar plugging criteria used in the steam generator tubes

  8. DNA Damage and Repair in Vascular Disease.

    Science.gov (United States)

    Uryga, Anna; Gray, Kelly; Bennett, Martin

    2016-01-01

    DNA damage affecting both genomic and mitochondrial DNA is present in a variety of both inherited and acquired vascular diseases. Multiple cell types show persistent DNA damage and a range of lesions. In turn, DNA damage activates a variety of DNA repair mechanisms, many of which are activated in vascular disease. Such DNA repair mechanisms either stall the cell cycle to allow repair to occur or trigger apoptosis or cell senescence to prevent propagation of damaged DNA. Recent evidence has indicated that DNA damage occurs early, is progressive, and is sufficient to impair function of cells composing the vascular wall. The consequences of persistent genomic and mitochondrial DNA damage, including inflammation, cell senescence, and apoptosis, are present in vascular disease. DNA damage can thus directly cause vascular disease, opening up new possibilities for both prevention and treatment. We review the evidence for and the causes, types, and consequences of DNA damage in vascular disease. PMID:26442438

  9. Establishment and application of a new method for the determination of kinetic parameters by plug-plug kinetic capillary electrophoresis (ppKCE)

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A novel plug-plug kinetic capillary electrophoresis method was established, which can be used to si-multaneously determine the kinetic parameters kon and koff in interaction systems. The method is comparatively simple and some restrictions in conventional ppKCE methods can be effectively avoided. The requirements for resolution and detection sensitivity in this method are much lower than those of conventional ppKCE. The successful determination of the kinetic parameters and the binding constant Kb between citalopram and BSA showed availability of this method. The results were confirmed by us-ing the time ratio method. The application field of kinetic capillary electrophoresis can be expanded with this new method.

  10. Establishment and application of a new method for the determination of kinetic parameters by plug-plug kinetic capillary electrophoresis (ppKCE)

    Institute of Scientific and Technical Information of China (English)

    XIONG CaiQiao; XIA ZhiNing; HUANG Rui; CHEN Hua; XU Pan

    2008-01-01

    A novel plug-plug kinetic capillary electrophoresis method was established, which can be used to si-multaneously determine the kinetic parameters kon and koff in interaction systems. The method is comparatively simple and some restrictions in conventional ppKCE methods can be effectively avoided, The requirements for resolution and detection sensitivity in this method are much lower than those of conventional ppKCE, The successful determination of the kinetic parameters and the binding constant Kb between citalopram and BSA showed availability of this method, The results were confirmed by us-ing the time ratio method. The application field of kinetic capillary electrophoresis can be expanded with this new method,

  11. Observation of the effect of cleaning the smear layer and tubule plugs with SEM

    Institute of Scientific and Technical Information of China (English)

    YU Dan-ni; DONG Ya-li

    2001-01-01

    To clean out the smear layer on teeth surface, and protect the teeth medulla, the experiment applied the study observing the cleanup of six groups of surface smear layer of dental caries and the tubule plugs reserving effect after using of different cavity cleansers with the help of SEM. The result implied that both the acidic preparations and chelator could clean out the smear layer on.teeth surface in some way, but the later one could also reserve partial tubule plugs, which reduce the stimulation to the teeth medulla. So the chelator is better cleansers in clinical use.

  12. Evaluation of a method of placing cross-sectional barriers during permanent plugging of wells

    OpenAIRE

    Sandven, Sondre

    2010-01-01

    When oil and gas wells reach the end of their production life, they need to be permanently plugged and abandoned. The requirements for a permanent barrier state that it must cover the entire cross-section of the wellbore, including all annuli. This thesis evaluates a new method of establishing a cross-sectional barrier in areas with poor, non-sealing annular cement. The traditional method is to mill away the section with poor cement and set an open hole cement plug, but due ...

  13. Performance, Charging, and Second-use Considerations for Lithium Batteries for Plug-in Electric Vehicles

    OpenAIRE

    Burke, Andrew

    2009-01-01

    This paper is concerned with batteries for use in plug-in electric vehicles. These vehicles use batteries that store a significant amount (kWh) of energy and thus will offer the possibilities for second-use in utility related applications such as residential and commercial backup systems and solar and wind generation systems. Cell test data are presented for the performance of lithium-ion batteries of several chemistries suitable for use in plug-in vehicles. The energy density of cells using ...

  14. Effects of gravity, inertia, and surfactant on steady plug propagation in a two-dimensional channel

    Science.gov (United States)

    Zheng, Y.; Fujioka, H.; Grotberg, J. B.

    2007-08-01

    Liquid plugs may form in pulmonary airways during the process of liquid instillation or removal in many clinical treatments. Studies have shown that the effectiveness of these treatments may depend on how liquids distribute in the lung. Better understanding of the fundamental fluid mechanics of liquid plug transport will facilitate treatment strategies. In this paper, we develop a numerical model of steady plug propagation driven by gravity and pressure in a two-dimensional liquid-lined channel oriented at an angle α with respect to gravity. We investigate the effects of gravity through the Bond number, Bo, and α; the plug propagation speed through the capillary number, Ca, or the Reynolds number, Re; the plug length LP, and the surfactant concentration C0. Without gravity, i.e., Bo =0, the plug is symmetric, and there are two regimes for the flow: two wall layers and two trapped vortices in the core. There is no flow interaction between the upper and lower half plug domains. When Bo ≠0 and α ≠0, π, fluid is found to flow from the upper precursor film, through the core and into the lower trailing film. Then the number of vortices can be zero, one, or two, depending on the flow parameters. The vortices have stagnation points on the interface when C0=0, however when the surfactant is present (C0>0), the vortices detach from the interface and create saddle points inside the core. The front meniscus develops a capillary surface wave extending into the precursor film. This is where the film is thinnest and thus the wall shear stress is highest, as high as ˜100dyn /cm2 in adult airways, which indicates a significant risk of pulmonary airway epithelial cell damage. Adding surfactant can decrease the peak magnitude of the shear stress, thus reducing the risk of cell damage. The prebifurcation asymmetry of the plug is quantified by the volume ratio, Vr, defined as the ratio of the liquid above to that below the center line of the channel. Vr is found to increase

  15. High level model predictive control for plug-and-play process control with stability guaranty

    DEFF Research Database (Denmark)

    Michelsen, Axel Gottlieb; Stoustrup, Jakob

    2010-01-01

    In this paper a method for designing a stabilizing high level model predictive controller for a hierarchical plug- and-play process is presented. This is achieved by abstracting the lower layers of the controller structure as low order models with uncertainty and by using a robust model predictive...... controller for generating the references for these. A simulation example, in which the actuators in a process control system are changed, is reported to show the potential of this approach for plug and play process control....

  16. Extraordinary Vessels Needling for Vascular Dementia

    Institute of Scientific and Technical Information of China (English)

    YU Jin; LAI Xin-sheng; HUANG Qiu-tang; XIAO Yuan-chun

    2003-01-01

    Purpose To observe the clinical efficacy of extraordinary vessels needling in treating vascular dementia. Method 39 cases vascular dementia were treated by acupoints selected from the eight extraordinary meridians and the time needling techniques such as eight methods of spiritual turtle, in accordance with time period and pattern identifition. Results 2 cases were cured, 30 cases improved and 7 cases failed; the total effective rate was 82.1%. Conclusion Extraordinary vessels needling has positive effects in treating vascular dementia.

  17. Vascular Risk Factors: Imaging and Neuropathologic Correlates

    OpenAIRE

    Knopman, David S; Roberts, Rosebud

    2010-01-01

    Cerebrovascular disease plays an important role in cognitive disorders in the elderly. Cerebrovascular disease and Alzheimer’s disease interact on several levels, one important level being the overlap in risk factors. The major vascular risk factors such as diabetes and impaired glycemic control, hypertension, obesity and hyper- or dyslipidemia have been associated both with Alzheimer’s disease and vascular dementia. The purpose of this review is to consider the context in which vascular deme...

  18. Blood Flow Restricted Exercise and Vascular Function

    OpenAIRE

    Masahiro Horiuchi; Koichi Okita

    2012-01-01

    It is established that regular aerobic training improves vascular function, for example, endothelium-dependent vasodilatation and arterial stiffness or compliance and thereby constitutes a preventative measure against cardiovascular disease. In contrast, high-intensity resistance training impairs vascular function, while the influence of moderate-intensity resistance training on vascular function is still controversial. However, aerobic training is insufficient to inhibit loss in muscular str...

  19. Plug-in混合动力汽车动力系统参数匹配%Parameter Matching of Powertrain in a Plug-in Hybrid Electric Vehicle

    Institute of Scientific and Technical Information of China (English)

    赵又群; 李佳

    2011-01-01

    Taking the parallel Plug-in hybrid electric vehicle as research object, the principle and implementing scheme of parameters matching for its powertrain were presented. As an example, the parameters matching for the powertrain of a car was conducted with car performance simulated using software ADVISOR. The simulation results were presented, which vertifies the prospective objects that is, the vehicle dynamic performance is equal to the prototype vehicle' s, fuel economy increases compared with the prototype vehicle' s.%以并联型Plug-in混合动力电动汽车(PHEV)为研究对象,提出了其动力驱动系统参数匹配的原则和实施方法.采用该方法对某型轿车动力总成参数进行了匹配,使用电动汽车仿真软件ADVISOR对整车性能进行仿真计算.仿真结果表明:Plug-in混合动力轿车动力性与原车相当,经济性与原车相比有很大提高,达到预期开发目标.

  20. VASCULAR MALFORMATION OF CHEEK: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Faiz

    2015-02-01

    Full Text Available Vascular lesions are among the most common congenital and neonatal abnormalities. Most of the congenital vascular malformations are often misdiagnosed and left untreated. These lesions are the result of an embryonic abnormality of the vascular system. This is a case report of 13 year male patient who came with a chief complaint of swelling on the right side of face since birth. It was diagnosed as vascular malformations of buccal mucosa of right side. It is emphasized that the management of these cases requ ires a multidisciplinary approach. Laser therapy, embolization followed by surgical excision is the favourable treatment modalities.

  1. Vascular endothelium - Gatekeeper of vessel health.

    Science.gov (United States)

    Cahill, Paul A; Redmond, Eileen M

    2016-05-01

    The vascular endothelium is an interface between the blood stream and the vessel wall. Changes in this single cell layer of the artery wall are believed of primary importance in the pathogenesis of vascular disease/atherosclerosis. The endothelium responds to humoral, neural and especially hemodynamic stimuli and regulates platelet function, inflammatory responses, vascular smooth muscle cell growth and migration, in addition to modulating vascular tone by synthesizing and releasing vasoactive substances. Compromised endothelial function contributes to the pathogenesis of cardiovascular disease; endothelial 'dysfunction' is associated with risk factors, correlates with disease progression, and predicts cardiovascular events. Therapies for atherosclerosis have been developed, therefore, that are directed towards improving endothelial function. PMID:26994427

  2. Proatherogenic pathways leading to vascular calcification

    Energy Technology Data Exchange (ETDEWEB)

    Mazzini, Michael J. [Department of Cardiology, Boston University Medical Center, Boston, MA (United States); Schulze, P. Christian [Department of Medicine, Boston University Medical Center, Boston, MA (United States)]. E-mail: christian.schulze@bmc.org

    2006-03-15

    Cardiovascular disease is the leading cause of morbidity and mortality in the western world and atherosclerosis is the major common underlying disease. The pathogenesis of atherosclerosis involves local vascular injury, inflammation and oxidative stress as well as vascular calcification. Vascular calcification has long been regarded as a degenerative process leading to mineral deposition in the vascular wall characteristic for late stages of atherosclerosis. However, recent studies identified vascular calcification in early stages of atherosclerosis and its occurrence has been linked to clinical events in patients with cardiovascular disease. Its degree correlates with local vascular inflammation and with the overall impact and the progression of atherosclerosis. Over the last decade, diverse and highly regulated molecular signaling cascades controlling vascular calcification have been described. Local and circulating molecules such as osteopontin, osteoprogerin, leptin and matrix Gla protein were identified as critical regulators of vascular calcification. We here review the current knowledge on molecular pathways of vascular calcification and their relevance for the progression of cardiovascular disease.

  3. Vascular grafting strategies in coronary intervention

    Science.gov (United States)

    Knight, Darryl; Gillies, Elizabeth; Mequanint, Kibret

    2014-06-01

    With the growing need for coronary revascularizations globally, several strategies to restore blood flow to the heart have been explored. Bypassing the atherosclerotic coronary arteries with autologous grafts, synthetic prostheses and tissue-engineered vascular grafts continue to be evaluated in search of a readily available vascular graft with clinically acceptable outcomes. The development of such a vascular graft including tissue engineering approaches both in situ and in vitro is herein reviewed, facilitating a detailed comparison on the role of seeded cells in vascular graft patency.

  4. Orthopedic issues in vascular anomalies.

    Science.gov (United States)

    Spencer, Samantha A; Sorger, Joel

    2014-08-01

    Vascular malformations impact the musculoskeletal system depending on the tissue involved (skin, subcutis, muscle, cartilage, or bone), the extent of involvement, and the type of anomalous vessels (arteries, capillaries, veins, or lymphatics). These malformations can cause a multitude of musculoskeletal problems for the patient and their Orthopedic Surgeon to manage. Leg-length discrepancy, intra-articular involvement, muscular lesions, and primary or secondary scoliosis are just to name a few. All of these problems can cause pain, deformity, and a range of functional limitations. Surgical and nonsurgical treatment plans both have a role in the care of these patients. Patients with vascular malformations may also suffer from life-threatening cardiovascular and hematologic abnormalities. For those patients who undergo surgery, thromboembolic risk is elevated, wound breakdown and infection are much more common, and bleeding risk continues well into the postoperative course. Because of the complex nature of these disorders, the clinician must have a full understanding of the types of lesions, their natural history, appropriate diagnostic studies, associated medical problems, indications for treatment, and all the treatment options. For severe malformations, especially syndromes such as CLOVES and Klippel-Trenaunay syndrome, interdisciplinary team management is essential for the best outcomes. PMID:25241103

  5. Diffuse and vascular hepatic diseases

    International Nuclear Information System (INIS)

    In addition to focal liver lesions, diffuse and vascular disorders of the liver represent a wide spectrum of liver diseases which are from the radiological point of view often difficult or nearly impossible to diagnose. Classical diagnostic methods are computed tomography and magnetic resonance imaging in addition to ultrasound. Diffuse parenchymal damage caused by diseases of various etiologies is therefore difficult to evaluate because it often lacks characteristic morphological features. For hepatic steatosis, hemochromatosis/siderosis as an example of a diffuse storage disease and sarcoidosis and candidiasis as infectious/inflammatory diseases, an image-based diagnosis is appropriate in some cases. For most diffuse liver diseases, however only nonspecific changes are visualized. Vascular pathologies of the liver, such as the Budd-Chiari syndrome and portal vein thrombosis, however, can usually be diagnosed very clearly using radiology and there is also a very effective interventional radiological treatment. Chronic diseases very often culminate in liver cirrhosis which is highly associated with an increased risk of liver cancer. (orig.)

  6. Neuroradiological findings in vascular dementia

    Energy Technology Data Exchange (ETDEWEB)

    Guermazi, Ali; Miaux, Yves; Suhy, Joyce; Pauls, Jon; Lopez, Ria [Synarc, Inc., Department of Radiology Services, San Francisco, CA (United States); Rovira-Canellas, Alex [Hospital General Universitari Vall d' Hebron, Unita de Resonancia Magnetica, Barcelona (Spain); Posner, Holly [Eisai, Inc., Teaneck, NJ (United States)

    2007-01-15

    There are multiple diagnostic criteria for vascular dementia (VaD) that may define different populations. Utilizing the criteria of the National Institute of Neurological Disorders and Stroke and Association Internationale pour la Recherche et l'Enseignement en Neurosciences (NINDS-AIREN) has provided improved consistency in the diagnosis of VaD. The criteria include a table listing brain imaging lesions associated with VaD. The different neuroradiological aspects of the criteria are reviewed based on the imaging data from an ongoing large-scale clinical trial testing a new treatment for VaD. The NINDS-AIREN criteria were applied by a centralized imaging rater to determine eligibility for enrollment in 1,202 patients using brain CT or MRI. Based on the above data set, the neuroradiological features that are associated with VaD and that can result from cerebral small-vessel disease with extensive leukoencephalopathy or lacunae (basal ganglia or frontal white matter), or may be the consequence of single strategically located infarcts or multiple infarcts in large-vessel territories, are illustrated. These features may also be the consequence of global cerebral hypoperfusion, intracerebral hemorrhage, or other mechanisms such as genetically determined arteriopathies. Neuroimaging confirmation of cerebrovascular disease in VaD provides information about the topography and severity of vascular lesions. Neuroimaging may also assist with the differential diagnosis of dementia associated with normal pressure hydrocephalus, chronic subdural hematoma, arteriovenous malformation or tumoral diseases. (orig.)

  7. Advance in molecular imaging research of vascular smooth muscle cells in the vascular diseases

    International Nuclear Information System (INIS)

    Vascular smooth muscle cells (VSMCs) are the primary cells within the vascular wall structure and maintain the tension of blood vessels, playing a key role in the restenosis, atherosclerosis and some other vascular diseases. With the development of molecular imaging, VSMCs cellular level of imaging studies is becoming more and more attention. The phenotype modulation, proliferation, migration and molecular imaging research progress of VSMCs in pathologic state were reviewed, to improve the management of vascular restenosis and atherosclerosis. (authors)

  8. Diabetes and ageing-induced vascular inflammation.

    Science.gov (United States)

    Assar, Mariam El; Angulo, Javier; Rodríguez-Mañas, Leocadio

    2016-04-15

    Diabetes and the ageing process independently increase the risk for cardiovascular disease (CVD). Since incidence of diabetes increases as people get older, the diabetic older adults represent the largest population of diabetic subjects. This group of patients would potentially be threatened by the development of CVD related to both ageing and diabetes. The relationship between CVD, ageing and diabetes is explained by the negative impact of these conditions on vascular function. Functional and clinical evidence supports the role of vascular inflammation induced by the ageing process and by diabetes in vascular impairment and CVD. Inflammatory mechanisms in both aged and diabetic vasculature include pro-inflammatory cytokines, vascular hyperactivation of nuclear factor-кB, increased expression of cyclooxygenase and inducible nitric oxide synthase, imbalanced expression of pro/anti-inflammatory microRNAs, and dysfunctional stress-response systems (sirtuins, Nrf2). In contrast, there are scarce data regarding the interaction of these mechanisms when ageing and diabetes co-exist and its impact on vascular function. Older diabetic animals and humans display higher vascular impairment and CVD risk than those either aged or diabetic, suggesting that chronic low-grade inflammation in ageing creates a vascular environment favouring the mechanisms of vascular damage driven by diabetes. Further research is needed to determine the specific inflammatory mechanisms responsible for exacerbated vascular impairment in older diabetic subjects in order to design effective therapeutic interventions to minimize the impact of vascular inflammation. This would help to prevent or delay CVD and the specific clinical manifestations (cognitive decline, frailty and disability) promoted by diabetes-induced vascular impairment in the elderly. PMID:26435167

  9. Smart Procurement of Naturally Generated Energy (SPONGE) for Plug-in Hybrid Electric Buses

    OpenAIRE

    Naoum-Sawaya, Joe; Crisostomi, Emanuele; Liu, Mingming; Gu, Yingqi; Shorten, Robert

    2016-01-01

    We discuss a recently introduced ECO-driving concept known as SPONGE in the context of Plug-in Hybrid Electric Buses (PHEB)'s.Examples are given to illustrate the benefits of this approach to ECO-driving. Finally, distributed algorithms to realise SPONGE are discussed, paying attention to the privacy implications of the underlying optimisation problems.

  10. Households' Stories of Their Encounters with a Plug-In Hybrid Electric Vehicle

    Science.gov (United States)

    Caperello, Nicolette D.; Kurani, Kenneth S.

    2012-01-01

    One way to progress toward greenhouse gas reductions is for people to drive plug-in hybrid electric vehicles (PHEVs). Households in this study participated in a 4- to 6-week PHEV driving trial. A narrative of each household's encounter with the PHEV was constructed by the researchers from multiple in-home interviews, questionnaires completed by…

  11. Research Experience with a Plug-In Hybrid Electric Vehicle: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Markel, T.; Pesaran, A.; Kelly, K.; Thornton, M.; Nortman, P.

    2007-12-01

    This technical document reports on the exploratory research conducted by NREL on PHEV technology using a Toyota Prius that has been converted to a plug-in hybrid electric vehicle. The data includes both controlled dynamometer and on-road test results, particularly for hilly driving. The results highlight the petroleum savings and benefits of PHEV technology.

  12. Energy management strategies for electric and plug-in hybrid electric vehicles

    CERN Document Server

    Williamson, Sheldon S

    2013-01-01

    Covers power electronics and motor drives for energy management of electric and plug-in hybrid electric vehicles Addresses specific issues and design solutions related to photovoltaic/grid based EV battery charging infrastructures and on-board battery management systems Emphasis on power electronic converter topologies for on-board battery management

  13. Effect of tube plugging in the thermalhydraulic performance of 'U' tube steam generators

    International Nuclear Information System (INIS)

    The thermalhydraulic performance of Angra II steam generator has been simulated using the model developed by Braga, C.V.M., 'Thermohydraulic model for steam generator of PWR power plants', in steady state, with plugging up to 40% of total number of tubes. (E.G.)

  14. Clean Cities Plug-In Electric Vehicle Handbook for Fleet Managers

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-04-01

    Plug-in electric vehicles (PEVs) are entering the automobile market and are viable alternatives to conventional vehicles. This guide for fleet managers describes the basics of PEV technology, PEV benefits for fleets, how to select the right PEV, charging a PEV, and PEV maintenance.

  15. Flowing catalyst particles in annular stream around a plug in lift pot

    Energy Technology Data Exchange (ETDEWEB)

    Skraba, F.W.

    1987-06-23

    A catalytic cracking process is described comprising (a) flowing a stream of hot cracking catalyst particles longitudinally through at least a portion of a lift pot in an annular stream around a plug which is positioned in the lift pot and which has an upstream end; a downstream end and a longitudinal axis; the hot cracking catalyst particles flow generally radially inwardly toward the plug axis past the downstream end of the plug, and then longitudinally into a riser-reactor; (b) introducing an oil feedstock into the stream of hot cracking catalyst particles as it is moving radially inwardly from around the periphery of the downstream end of the plug for the formation of a reaction mixture with the hot cracking catalyst. The hot catalyst particles and the oil feedstock moves at approximately right angles to each other at the point at which the oil feedstock is introduced; and (c) flowing the reaction mixture through the riser-reactor and into a disengagement chamber. The mixture flows into the disengagement chamber comprising cracked oil product and catalyst particles.

  16. Intranasal caseous fibrinous plug causing upper respiratory distress in two African grey parrots (Psittacus erithacus).

    Science.gov (United States)

    Burr, E W

    1981-01-01

    Two cases of intranasal caseous fibrinous plugs causing upper respiratory distress in two African grey parrots are described. The causal bacterial agents in one case were Klebsiella spp., Bacillus mycoides, Staphylococcus epidermitis, and Pasteurella multocida. Both cases produced pressure necrosis and obstruction of the naris. PMID:7259689

  17. Dispersed plug flow model for upflow anaerobic sludge bed reactors with focus on granular sludge dynamics

    NARCIS (Netherlands)

    Kalyuzhnyi, S.V.; Fedorovich, V.V.; Lens, P.N.L.

    2006-01-01

    A new approach to model upflow anaerobic sludge bed (UASB)-reactors, referred to as a one-dimensional dispersed plug flow model, was developed. This model focusses on the granular sludge dynamics along the reactor height, based on the balance between dispersion, sedimentation and convection using on

  18. 40 CFR 144.62 - Cost estimate for plugging and abandonment.

    Science.gov (United States)

    2010-07-01

    ... Oil and Gas Field Equipment Cost Index. The inflation factor is the result of dividing the latest... abandonment. 144.62 Section 144.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER... Waste Injection Wells § 144.62 Cost estimate for plugging and abandonment. (a) The owner or...

  19. Method of start-up of rotary plug sealing devices in FBR type reactors

    International Nuclear Information System (INIS)

    Purpose: To rapidly and safely start-up the rotary plug sealing device by controlling to eliminate the pressure difference in the pressures of gases exerting on the liquid surfaces in the inner and the outer cylinders of a sealing alloy vessel in the rotary plug of a FBR type reactor. Method: In a case where an abnormal state results in the pressure difference of gases exerted on the liquid surfaces in the inner and the outer cylinders of a vessel charged with sealing alloy in a rotary plug and the sealing valve for the back-up gas supply tube is rapidly closed to seal the sealing portion, the pressure in the gas supply tube is controlled so that the pressure difference in the gases exerted on the liquid surfaces in the inner and outer cylinders while closing the sealing valve. Then, after conforming that the pressure is controlled to a predetermined level at which the pressure difference can be regarded to be zero, the sealing valve is gradually opened while regulating the pressure in the gas supply tube so as to maintain the pressure difference to a predetermined level. This prevents the occurrence of external disturbances upon opening of the sealing valve and enables rapid and safety start-up for the rotary plug sealing device. (Moriyama, K.)

  20. Combined fuel assembly and thimble plug gripper for a nuclear reactor

    International Nuclear Information System (INIS)

    This invention relates to an apparatus for loading and unloading a fuel assembly into and from the core of a nuclear reactor and for removing and inserting control rod guide thimble plugs from and into the fuel assembly during a reactor refueling operation in substantially less time than that presently required and in a more reliable, safe and efficient manner. (UK)