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Sample records for amgdala preliminary evidence

  1. Measuring immigration policies: preliminary evidence from IMPALA

    NARCIS (Netherlands)

    Beine, M.; Burgoon, B.M.; Crock, M.; Gest, J.; Hiscox, M.; McGovern, P.; Rapoport, H.; Thielemann, E.

    2015-01-01

    This article presents the methods and preliminary findings from IMPALA, a database that systematically measures the character and stringency of immigration policies. Based on a selection of data for six pilot countries between 1990 and 2008, we document the variation of immigration policies across

  2. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    Directory of Open Access Journals (Sweden)

    Maryam Kazemi

    2013-12-01

    Full Text Available Each year, over a billion Muslims fast worldwide during the month of Ramadan.  Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to the persistent gap between current expert knowledge and conclusive, strong evidence regarding the pathophysiologic and metabolic alterations by fasting, and the consensus that healthcare professionals should reach, in order to manage various patient groups during this month. In this review, we summarize the results of our initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition. We also go through the important clinical results of patients who have had previous history of cardiovascular disease, type 2 diabetes, asthma and renal colic. Our studies have presented some evidence in favor of Ramadan fasting and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. We attempt to present some relevant evidence clarify future scopes in this area of study, and provide suggestions for future investigations.

  3. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    Directory of Open Access Journals (Sweden)

    1Maryam Kazemi

    2013-11-01

    Full Text Available Each year, over a billion Muslims fast worldwide during the month of Ramadan. Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to the persistent gap between current expert knowledge and conclusive, strong evidence regarding the pathophysiologic and metabolic alterations by fasting, and the consensus that healthcare professionals should reach, in order to manage various patient groups during this month. In this review, we summarize the results of our initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition. We also go through the important clinical results of patients who have had previous history of cardiovascular disease, type 2 diabetes, asthma and renal colic. Our studies have presented some evidence in favor of Ramadan fasting and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. We attempt to present some relevant evidence clarify future scopes in this area of study, and provide suggestions for future investigations.

  4. Emergent Writing in Preschoolers: Preliminary Evidence for a Theoretical Framework

    Science.gov (United States)

    Puranik, Cynthia S.; Lonigan, Christopher J.

    2014-01-01

    Researchers and educators use the term emergent literacy to refer to a broad set of skills and attitudes that serve as foundational skills for acquiring success in later reading and writing; however, models of emergent literacy have generally focused on reading and reading-related behaviors. Hence, the primary aim of this study was to articulate and evaluate a theoretical model of the components of emergent writing. Alternative models of the structure of individual and developmental differences of emergent writing and writing-related skills were examined in 372 preschool children who ranged in age from 3- to 5-years using confirmatory factor analysis. Results from a confirmatory factor analysis provide evidence that these emergent writing skills are best described by three correlated but distinct factors, (a) Conceptual Knowledge, (b) Procedural Knowledge, and (c) Generative Knowledge. Evidence that these three emergent writing factors show different patterns of relations to emergent literacy constructs is presented. Implications for understanding the development of writing and assessment of early writing skills are discussed. PMID:25316955

  5. School Improvement Plans and Student Achievement: Preliminary Evidence from the Quality and Merit Project in Italy

    Science.gov (United States)

    Caputo, Andrea; Rastelli, Valentina

    2014-01-01

    This study provides preliminary evidence from an Italian in-service training program addressed to lower secondary school teachers which supports school improvement plans (SIPs). It aims at exploring the association between characteristics/contents of SIPs and student improvement in math achievement. Pre-post standardized tests and text analysis of…

  6. Deep Brain Stimulation in Huntington’s Disease—Preliminary Evidence on Pathophysiology, Efficacy and Safety

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    Lars Wojtecki

    2016-08-01

    Full Text Available Huntington’s disease (HD is one of the most disabling degenerative movement disorders, as it not only affects the motor system but also leads to cognitive disabilities and psychiatric symptoms. Deep brain stimulation (DBS of the pallidum is a promising symptomatic treatment targeting the core motor symptom: chorea. This article gives an overview of preliminary evidence on pathophysiology, safety and efficacy of DBS in HD.

  7. Neuroplasticity of selective attention: Research foundations and preliminary evidence for a gene by intervention interaction.

    Science.gov (United States)

    Isbell, Elif; Stevens, Courtney; Pakulak, Eric; Hampton Wray, Amanda; Bell, Theodore A; Neville, Helen J

    2017-08-29

    This article reviews the trajectory of our research program on selective attention, which has moved from basic research on the neural processes underlying selective attention to translational studies using selective attention as a neurobiological target for evidence-based interventions. We use this background to present a promising preliminary investigation of how genetic and experiential factors interact during development (i.e., gene × intervention interactions). Our findings provide evidence on how exposure to a family-based training can modify the associations between genotype (5-HTTLPR) and the neural mechanisms of selective attention in preschool children from lower socioeconomic status backgrounds.

  8. Neuroplasticity of selective attention: Research foundations and preliminary evidence for a gene by intervention interaction

    Science.gov (United States)

    Stevens, Courtney; Pakulak, Eric; Hampton Wray, Amanda; Bell, Theodore A.; Neville, Helen J.

    2017-01-01

    This article reviews the trajectory of our research program on selective attention, which has moved from basic research on the neural processes underlying selective attention to translational studies using selective attention as a neurobiological target for evidence-based interventions. We use this background to present a promising preliminary investigation of how genetic and experiential factors interact during development (i.e., gene × intervention interactions). Our findings provide evidence on how exposure to a family-based training can modify the associations between genotype (5-HTTLPR) and the neural mechanisms of selective attention in preschool children from lower socioeconomic status backgrounds. PMID:28819066

  9. Preliminary evidence for an automatic link between sex and power among men who molest children.

    Science.gov (United States)

    Kamphuis, Jan H; De Ruiter, Corine; Janssen, Bas; Spiering, Mark

    2005-11-01

    Understanding critical motivational processes of sexual offenders may ultimately provide important clues to more effective treatments. Implicit, automatic cognitive processes have received minimal attention; however, a lexical decision experiment revealed automatic links between the concepts of power and sex among participants who self-reported attraction to sexual aggression. The current study replicates this experiment with a group of male child molesters and forensic and analogue controls. Subliminally presented sex words elicited a facilitation effect for power words among child molesters only; that is, sex to power associations were evident, as well as a trend for the reverse. These results provide preliminary evidence for an automatic sex-power association in child molesters and may point to a crucial pathological link in the cognitive schemata of sex offenders. As well, the current study suggests that paradigms from cognitive psychology may contribute to multimodal (risk) assessment of sexual offenders.

  10. Diffusion Imaging of Auditory and Auditory-Limbic Connectivity in Tinnitus: Preliminary Evidence and Methodological Challenges

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    Anna Seydell-Greenwald

    2014-01-01

    Full Text Available Subjective tinnitus, or “ringing in the ears,” is perceived by 10 to 15 percent of the adult population and causes significant suffering in a subset of patients. While it was originally thought of as a purely auditory phenomenon, there is increasing evidence that the limbic system influences whether and how tinnitus is perceived, far beyond merely determining the patient’s emotional reaction to the phantom sound. Based on functional imaging and electrophysiological data, recent articles frame tinnitus as a “network problem” arising from abnormalities in auditory-limbic interactions. Diffusion-weighted magnetic resonance imaging is a noninvasive method for investigating anatomical connections in vivo. It thus has the potential to provide anatomical evidence for the proposed changes in auditory-limbic connectivity. However, the few diffusion imaging studies of tinnitus performed to date have inconsistent results. In the present paper, we briefly summarize the results of previous studies, aiming to reconcile their results. After detailing analysis methods, we then report findings from a new dataset. We conclude that while there is some evidence for tinnitus-related increases in auditory and auditory-limbic connectivity that counteract hearing-loss related decreases in auditory connectivity, these results should be considered preliminary until several technical challenges have been overcome.

  11. Ability of baclofen in reducing alcohol craving and intake: II--Preliminary clinical evidence.

    Science.gov (United States)

    Addolorato, G; Caputo, F; Capristo, E; Colombo, G; Gessa, G L; Gasbarrini, G

    2000-01-01

    Accumulating evidence shows the efficacy of the gamma-aminobutyric acid (GABA(B)) receptor agonist baclofen in reducing alcohol intake in rats, but no studies have been performed in alcoholics. In the present preliminary study we investigated the effect of short-term baclofen administration on craving for alcohol, ethanol intake, and abstinence from alcohol in alcoholic individuals. Ten male current alcoholic individuals were admitted to the study. Baclofen was orally administered for 4 weeks, at a dose of 15 mg/day refracted in three times per day for the first 3 days, with the dose increased to 30 mg/day for the remaining 27 days. Each subject was checked as an outpatient every week for the 4 weeks; at each visit (T0-T4) craving level was evaluated by the Alcohol Craving Scale (ACS), and abstinence from alcohol was assessed based on the individual's self-evaluation, family member interview, and the main biological markers of alcohol abuse. A self-reported alcohol intake was recorded as the mean number of standard drinks consumed per day. Nine subjects completed the study; of these, two subjects continued to drink alcohol although they substantially reduced their daily drinks in the first week of treatment, whereas seven maintained abstinence throughout the experimental period. Craving was significantly reduced from the first week of the drug administration (p alcohol disappeared. Values of gamma-glutamyltranspeptidase, alanine aminotransferase, and mean cellular volume significantly decreased by the end of the study. Tolerability was fair in all participants; headache, vertigo, nausea, constipation, diarrhea, abdominal pain, hypotension, increased sleepiness, and tiredness were present as side effects in the first stage of the treatment. No participants showed craving for the drug. With the limitations of the low number of individuals evaluated and the open design, this preliminary clinical study supports the preclinical evidence on the effect of baclofen in

  12. The Influence of Sleep on the Consolidation of Positive Emotional Memories: Preliminary Evidence

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    Alexis M. Chambers

    2014-05-01

    Full Text Available Studies have not only shown that a period of sleep following learning offers greater benefits to later memory than a period of wakefulness, but also that sleep actively promotes those components of memories that are emotionally salient. However, sleep's role in emotional memory consolidation has largely been investigated with memories that are specifically negative in content, such as memory for negative images or texts, leaving open the question of whether sleep influences positive memories in a similar manner. The current study investigated the emotional memory trade-off effect for positive versus neutral information. Scenes in which a positive or neutral object was placed on a neutral background were encoded prior to a period of polysomnographically-monitored nocturnal sleep or daytime wakefulness. Recognition memory was tested for the objects and backgrounds separately following the delay using the Remember/Know paradigm. Compared to wake participants, those who slept during the delay had increased recollection memory performance for positive objects, but not the neutral components of the studied scenes. Further, familiarity of positive objects was negatively correlated with REM latency. These results provide preliminary evidence that sleep contributes to the selective processing of positive memories, and point toward a role for REM sleep in positive memory formation.

  13. The medication experience: preliminary evidence of its value for patient education and counseling on chronic medications.

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    Shoemaker, Sarah J; Ramalho de Oliveira, Djenane; Alves, Mateus; Ekstrand, Molly

    2011-06-01

    To describe medication therapy management (MTM) pharmacists' encounters with patients' medication experiences, to examine the utility of the medication experience in practice, and to explore the value of the medication experience in patient education and counseling on medications. A focus group of 10 MTM pharmacists, and 1 pharmacist's 9-month practice diary were analyzed to reveal patients' medication experiences and the utility and value of the medication experience in practice. MTM pharmacists commonly encountered patients' medication experiences in their practices. The medication experience was often at the root of drug therapy problems (DTPs) the practitioners identified. The pharmacists identified several examples of drug therapy problems with an associated medication experience at the root. The medication experience was a meaningful construct to guide patient education and counseling on new chronic medications to ultimately prevent DTPs, and valuable for tailoring patient education and counseling on medications to resolve DTPs. Our study provides preliminary evidence of the value of the medication experience for patient education and counseling on chronic medications in practice. The medication experience is a valuable tool for practitioners to understand patients' needs, identify and resolve DTPs, and tailor patient education and counseling for chronic medications. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  14. What is driving rates of social policy preliminary references to the CJEU? Evidence from the United Kingdom and France.

    Science.gov (United States)

    Sigafoos, Jennifer

    2012-12-01

    Preliminary references to the Court of Justice for the European Union are unevenly distributed across the EU, creating differing access to justice for European citizens. This study presents case studies of the UK and France, exploring factors affecting rates of social policy preliminary references from 1996-2009. The UK had a rate twice that of France. What accounts for this difference? Analysis of documentary evidence and 25 expert interviews help to explain the differing rates. Themes were related to policy, structural factors and the agency of actors. In the UK, policy themes are the free movement of persons and the 'Right to Reside' test. Legal aid and legal NGOs help individuals access the Court and drive test case strategies. In France, a high degree of dualisation in the welfare state creates an insider/outsider dynamic. Coupled with the resistance of courts and a lack of comparable actors to drive preliminary references, this contributes to a lower rate of references.

  15. Preliminary Evidence for a Virial Shock around the Coma Galaxy Cluster

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    Keshet, Uri; Kushnir, Doron; Loeb, Abraham; Waxman, Eli

    2017-08-01

    Galaxy clusters, the largest gravitationally bound objects in the universe, are thought to grow by accreting mass from their surroundings through large-scale virial shocks. Due to electron acceleration in such a shock, it should appear as a γ-ray, hard X-ray, and radio ring, elongated toward the large-scale filaments feeding the cluster, coincident with a cutoff in the thermal Sunyaev-Zel’dovich (SZ) signal. However, no such signature was found until now, and the very existence of cluster virial shocks has remained a theory. We find preliminary evidence for a large γ-ray ring of ˜ 5 {Mpc} minor axis around the Coma cluster, elongated toward the large-scale filament connecting Coma and Abell 1367, detected at the nominal 2.7σ confidence level (5.1σ using control signal simulations). The γ-ray ring correlates both with a synchrotron signal and with the SZ cutoff, but not with Galactic tracers. The γ-ray and radio signatures agree with analytic and numerical predictions if the shock deposits ˜ 1 % of the thermal energy in relativistic electrons over a Hubble time and ˜ 1 % in magnetic fields. The implied inverse Compton and synchrotron cumulative emission from similar shocks can contribute significantly to the diffuse extragalactic γ-ray and low-frequency radio backgrounds. Our results, if confirmed, reveal the prolate structure of the hot gas in Coma, the feeding pattern of the cluster, and properties of the surrounding large-scale voids and filaments. The anticipated detection of such shocks around other clusters would provide a powerful new cosmological probe.

  16. Reliability and preliminary evidence of validity of a Farsi version of the depression anxiety stress scales.

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    Bayani, Ali Asghar

    2010-08-01

    The internal consistency, test-retest reliability, and construct validity of the Farsi version of the Depression Anxiety Stress Scales were examined, with a sample of 306 undergraduate students (123 men, 183 women) ranging from 18 to 51 years of age (M age = 25.4, SD = 6.1). Participants completed the Satisfaction with Life Scale, Rosenberg Self-esteem Scale, and the Depression Anxiety Stress Scales. The findings confirmed the preliminary reliabilities and preliminary construct validity of the Farsi translation of the Depression Anxiety Stress Scales.

  17. Clinical utility of color-form naming in Alzheimer's disease: preliminary evidence

    DEFF Research Database (Denmark)

    Nielsen, Niels Peter; Wiig, Elisabeth H; Warkentin, Siegbert

    2004-01-01

    Performances on Alzheimer's Quick Test color-form naming and Mini-Mental State Examination were compared for 38 adults with Alzheimer's disease and 38 age- and sex-matched normal controls. Group means differed significantly and indicated longer naming times by adults with Alzheimer's disease...... associated with Alzheimer's disease, are preliminary given the relatively small sample....

  18. Preliminary Evidence for Cognitive Mediation During Cognitive–Behavioral Therapy of Panic Disorder

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    Hofmann, Stefan G.; Suvak, Michael K.; Barlow, David H.; Shear, M. Katherine; Meuret, Alicia E.; Rosenfield, David; Gorman, Jack M.; Woods, Scott W.

    2007-01-01

    Cognitive–behavioral therapy (CBT) and pharmacotherapy are similarly effective for treating panic disorder with mild or no agoraphobia, but little is known about the mechanism through which these treatments work. The present study examined some of the criteria for cognitive mediation of treatment change in CBT alone, imipramine alone, CBT plus imipramine, and CBT plus placebo. Ninety-one individuals who received 1 of these interventions were assessed before and after acute treatment, and after a 6-month maintenance period. Multilevel moderated mediation analyses provided preliminary support for the notion that changes in panic-related cognitions mediate changes in panic severity only in treatments that include CBT. PMID:17563154

  19. Transport processes for Chernobyl-labelled sediments: preliminary evidence from upland mid-Wales

    International Nuclear Information System (INIS)

    Bonnett, P.J.P.; Leeks, G.J.L.; Cambray, R.S.

    1989-01-01

    The nuclear accident at Chernobyl in April 1986 resulted in a significant increase in the inventory of radiocaesium retained in the soil in many regions of the United Kingdom. The deposition of 134 Cs provides a convenient tool for the examination of erosional processes in upland systems. Detailed soil sampling has been undertaken within the Plynlimon experimental catchments to establish the pattern of deposition of Chernobyl-derived radionuclides. The preliminary results of a combined radiometric and mineral magnetic approach to the study of the transport of Chernobyl-labelled sediments and their source areas on these upland catchments in mid-Wales are described. (author)

  20. Preliminary Evidence on the Efficacy of Mindfulness Combined with Traditional Classroom Management Strategies.

    Science.gov (United States)

    Kasson, Erin M; Wilson, Alyssa N

    2017-09-01

    The current case study combined mindfulness-based strategies with a classroom behavior management treatment package, to assist teachers with managing 3rd grade student behaviors. Two teachers (Classroom teacher and Specials teacher) and six students within the same classroom were observed using a 5-min momentary time sampling procedure. A delayed multiple baseline across settings (e.g., Classroom teacher, Specials teacher) design was used to assess student behaviors across baseline (A), classroom behavior management treatment package (CBM) (B), CBM plus mindfulness (C), and CBM plus mindfulness and self-monitoring (D). Behavioral treatment alone increased on-task behaviors for four of six (66%) students compared to baseline; however, five of six (83%) students increased and sustained high rates of on-task behaviors when mindfulness exercises were added to the behavior analytic techniques. These preliminary results support the combination of mindfulness-based strategies with traditional behavior analytic interventions for increasing student on-task behaviors in classroom settings.

  1. Adapting Evidence-Based Mental Health Treatments in Community Settings: Preliminary Results from a Partnership Approach

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    Southam-Gerow, Michael A.; Hourigan, Shannon E.; Allin, Robert B., Jr.

    2009-01-01

    This article describes the application of a university-community partnership model to the problem of adapting evidence-based treatment approaches in a community mental health setting. Background on partnership research is presented, with consideration of methodological and practical issues related to this kind of research. Then, a rationale for…

  2. Recruiting for Values in Healthcare: A Preliminary Review of the Evidence

    Science.gov (United States)

    Patterson, Fiona; Prescott-Clements, Linda; Zibarras, Lara; Edwards, Helena; Kerrin, Maire; Cousans, Fran

    2016-01-01

    Displaying compassion, benevolence and respect, and preserving the dignity of patients are important for any healthcare professional to ensure the provision of high quality care and patient outcomes. This paper presents a structured search and thematic review of the research evidence relating to values-based recruitment within healthcare. Several…

  3. Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study.

    Science.gov (United States)

    Keszthelyi, D; Troost, F J; Jonkers, D M; van Eijk, H M; Dekker, J; Buurman, W A; Masclee, A A M

    2015-08-01

    Altered serotonergic (5-HT) metabolism and visceral perception have been associated with the pathogenesis of irritable bowel syndrome (IBS). Aim of this preliminary study was to assess the effect of the direct precursor of 5-HT, 5-hydroxytryptophan (5-HTP), on systemic 5-HT metabolites and visceral perception and to assess potential differential responses between IBS and controls. 15 IBS patients and 15 healthy volunteers participated in this randomized double-blind placebo controlled study. Visceroperception was measured by rectal barostat. The 100 mg 5-HTP or placebo was ingested orally. Serotonergic metabolites were assessed in platelet poor plasma. 5-HTP induces rectal allodynia in a significant number of healthy controls; IBS patients exhibit lowered pain thresholds in both placebo and 5-HTP conditions. 5-HTP induces rectal hyperalgesia in hypersensitive but not in non-hypersensitive IBS patients. Administration of 5-HTP significantly increased plasma 5-HTP levels (p 0.05), while levels of the main metabolite of 5-HT, 5-hydroxyindoleacetic acid, increased significantly (p HTP induced significant alterations in systemic 5-HT metabolites that were accompanied by increased visceroperception of pain in controls and hypersensitive IBS patients. Changes in 5-HT metabolism appear to be important factors involved in visceral hypersensitivity as the 5-HTP-induced pro-nociceptive response was observed in all hypersensitive IBS patients and to a lesser magnitude in a significant number of healthy controls but in none of the non-hypersensitive IBS patients. © 2015 John Wiley & Sons Ltd.

  4. Preliminary Evidence for the Amplification of Global Warming in Shallow, Intertidal Estuarine Waters.

    Science.gov (United States)

    Oczkowski, Autumn; McKinney, Richard; Ayvazian, Suzanne; Hanson, Alana; Wigand, Cathleen; Markham, Erin

    2015-01-01

    Over the past 50 years, mean annual water temperature in northeastern U.S. estuaries has increased by approximately 1.2°C, with most of the warming recorded in the winter and early spring. A recent survey and synthesis of data from four locations in Southern Rhode Island has led us to hypothesize that this warming may be amplified in the shallow (<1 m), nearshore portions of these estuaries. While intertidal areas are not typically selected as locations for long-term monitoring, we compiled data from published literature, theses, and reports that suggest that enhanced warming may be occurring, perhaps at rates three times higher than deeper estuarine waters. Warmer spring waters may be one of the factors influencing biota residing in intertidal regions both in general as well as at our specific sites. We observed greater abundance of fish, and size of Menidia sp., in recent (2010-2012) seine surveys compared to similar collections in 1962. While any linkages are speculative and data are preliminary, taken together they suggest that shallow intertidal portions of estuaries may be important places to look for the effects of climate change.

  5. Preliminary Evidence for the Amplification of Global Warming in Shallow, Intertidal Estuarine Waters.

    Directory of Open Access Journals (Sweden)

    Autumn Oczkowski

    Full Text Available Over the past 50 years, mean annual water temperature in northeastern U.S. estuaries has increased by approximately 1.2°C, with most of the warming recorded in the winter and early spring. A recent survey and synthesis of data from four locations in Southern Rhode Island has led us to hypothesize that this warming may be amplified in the shallow (<1 m, nearshore portions of these estuaries. While intertidal areas are not typically selected as locations for long-term monitoring, we compiled data from published literature, theses, and reports that suggest that enhanced warming may be occurring, perhaps at rates three times higher than deeper estuarine waters. Warmer spring waters may be one of the factors influencing biota residing in intertidal regions both in general as well as at our specific sites. We observed greater abundance of fish, and size of Menidia sp., in recent (2010-2012 seine surveys compared to similar collections in 1962. While any linkages are speculative and data are preliminary, taken together they suggest that shallow intertidal portions of estuaries may be important places to look for the effects of climate change.

  6. Knowledge of evidence-based dentistry among academic dental practitioners of Bhopal, India: a preliminary survey

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    Aishwarya Singh

    2015-06-01

    Full Text Available This study aimed to characterize the knowledge of evidence-based dentistry (EBD among dental faculty members in the city of Bhopal in central India. A cross-sectional questionnaire was administered at two dental colleges in Bhopal City. All dental faculty members who were present on the day of the study and who agreed to participate were included in the study. A total of 50 dental faculty members returned the questionnaire. Six Likert-type questions were asked, and the percentages of various responses were used for analysis. Sixteen faculty members (32.0% strongly agreed that EBD is a process of making decisions based on scientifically proven evidence. Fifteen faculty members (30.0% strongly disagreed or disagreed with the item stating that the best and quickest way to find evidence is by reading textbooks or asking experienced colleagues. Thirteen faculty members (26.0% strongly agreed that EBD allows dentists to improve their scientific knowledge and clinical skills. It is recommended that EBD be included in undergraduate and postgraduate curricula and in intensive continuing dental education programs that are conducted for dental faculty members.

  7. Bridging psychophysiological and phenomenological characteristics of psychosis--Preliminary evidence for the relevance of emotion regulation.

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    Clamor, Annika; Schlier, Björn; Köther, Ulf; Hartmann, Maike M; Moritz, Steffen; Lincoln, Tania M

    2015-12-01

    In psychosis, the alleged increased subjective stress-sensitivity is reflected in abnormal physiological arousal such as higher heart rate, elevated skin conductance levels, decreased vagal activity, and unusual cortisol levels. Despite ongoing research, possible mechanisms that explain the interplay between the phenomenological (i.e., subjective stress and symptoms) and psychophysiological processes are not thoroughly understood. Building on the model of neurovisceral integration by Thayer and Lane (2000) that focuses on regulative mechanisms, we postulate that emotion regulation will be associated with vagal activity, and with both subjective and physiological stress. In the present analysis, we used data from a baseline relaxation period including a 5-minute assessment of heart rate variability (HRV), salivary cortisol, and momentary subjective stress ratings from a sample of 19 participants with psychosis (mean age=40.9, SD=11.1; 36.8% female). Emotion regulation modification skills were assessed for specific emotions (i.e., stress and arousal, anxiety, anger, sadness, shame) if these were present during the previous week. Vagal HRV was significantly and moderately associated with emotion regulation. Both stress parameters (i.e., cortisol, subjective stress) were significantly associated with emotion regulation, but not with HRV. We provide preliminary support for the notion that emotion regulatory processes represent a crucial link between phenomenological and psychophysiological phenomena in psychosis. A potential model that ascribes emotion regulation a central role in the restoration of homeostasis is discussed. Future studies are needed to verify its generalizability and predictive value. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Preliminary evidence for a change in spectral sensitivity of the circadian system at night

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    Parsons Robert H

    2005-12-01

    Full Text Available Abstract Background It is well established that the absolute sensitivity of the suprachiasmatic nucleus to photic stimulation received through the retino-hypothalamic tract changes throughout the 24-hour day. It is also believed that a combination of classical photoreceptors (rods and cones and melanopsin-containing retinal ganglion cells participate in circadian phototransduction, with a spectral sensitivity peaking between 440 and 500 nm. It is still unknown, however, whether the spectral sensitivity of the circadian system also changes throughout the solar day. Reported here is a new study that was designed to determine whether the spectral sensitivity of the circadian retinal phototransduction mechanism, measured through melatonin suppression and iris constriction, varies at night. Methods Human adult males were exposed to a high-pressure mercury lamp [450 lux (170 μW/cm2 at the cornea] and an array of blue light emitting diodes [18 lux (29 μW/cm2 at the cornea] during two nighttime experimental sessions. Both melatonin suppression and iris constriction were measured during and after a one-hour light exposure just after midnight and just before dawn. Results An increase in the percentage of melatonin suppression and an increase in pupil constriction for the mercury source relative to the blue light source at night were found, suggesting a temporal change in the contribution of photoreceptor mechanisms leading to melatonin suppression and, possibly, iris constriction by light in humans. Conclusion The preliminary data presented here suggest a change in the spectral sensitivity of circadian phototransduction mechanisms at two different times of the night. These findings are hypothesized to be the result of a change in the sensitivity of the melanopsin-expressing retinal ganglion cells to light during the night.

  9. Preliminary evidence of apathetic-like behavior in aged vesicular monoamine transporter 2 deficient mice

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    Aron Baumann

    2016-11-01

    Full Text Available Apathy is considered to be a core feature of Parkinson’s disease (PD and has been associated with a variety of states and symptoms of the disease, such as increased severity of motor symptoms, impaired cognition, executive dysfunction, and dementia. Apart from the high prevalence of apathy in PD, which is estimated to be about 40%, the underlying pathophysiology remains poorly understood and current treatment approaches are unspecific and proved to be only partially effective. In animal models, apathy has been sub-optimally modeled, mostly by means of pharmacological and stress-induced methods, whereby concomitant depressive-like symptoms could not be ruled out. In the context of PD only a few studies on toxin-based models (i.e. 6-OHDA or MPTP claimed to have determined apathetic symptoms in animals. The assessment of apathetic symptoms in more elaborated and multifaceted genetic animal models of PD could help to understand the pathophysiological development of apathy in PD and eventually advance specific treatments for afflicted patients. Here we report the presence of behavioral signs of apathy in 12 months old mice that express only ~5% of the vesicular monoamine transporter 2 (VMAT2. Apathetic-like behavior in VMAT2 deficient (LO mice was evidenced by impaired burrowing and nest building skills, and a reduced preference for sweet solution in the saccharin preference test, while the performance in the forced swimming test was normal. Our preliminary results suggest that VMAT2 deficient mice show an apathetic-like phenotype that might be independent of depressive-like symptoms. Therefore VMAT2 LO mice could be a useful tool to study of the pathophysiological substrates of apathy and to test novel treatment strategies for apathy in the context of PD.

  10. Scale Dependence of the Effective Matrix Diffusion Coefficient : Evidence and Preliminary Interpretation

    International Nuclear Information System (INIS)

    H.H. Liu; Y. Zhang

    2006-01-01

    matrix-diffusion coefficient, and to -develop a preliminary explanation for this scale-dependent behavior

  11. Biogeochemical evidence for subsurface hydrocarbon occurrence, Recluse oil field, Wyoming; preliminary results

    Science.gov (United States)

    Dalziel, Mary C.; Donovan, Terrence J.

    1980-01-01

    Anomalously high manganese-to-iron ratios occurring in pine needles and sage leaves over the Recluse oil field, Wyoming, suggest effects of petroleum microseepage on the plants. This conclusion is supported by iron and manganese concentrations in soils and carbon and oxygen isotope ratios in rock samples. Seeping hydrocarbons provided reducing conditions sufficient to enable divalent iron and manganese to be organically complexed or adsorbed on solids in the soils. These bound or adsorped elements in the divalent state are essential to plants, and the plants readily assimilate them. The magnitude of the plant anomalies, combined with the supportive isotopic and chemical evidence confirming petroleum leakage, makes a strong case for the use of plants as a biogeochemical prospecting tool.

  12. Opportunity of objective account of the colorimetric procedure using benzidine indicative at establishing the preliminary presence of blood on the material evidences

    Directory of Open Access Journals (Sweden)

    A. V. Konovalenko

    2015-01-01

    Full Text Available The article presents a modification of the colorimetric method for the preliminary establishment of presence of blood in the stainson the material evidences using benzidine test. The proposed modification is accompanied by photometric accounting and computer processing of the results. Performance, objectivity, as well as other features and advantages of this method when used in forensic practice are described in detail.

  13. Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Maya Weinstein

    2015-01-01

    Full Text Available Neuroplasticity studies examining children with hemiparesis (CH have focused predominantly on unilateral interventions. CH also have bimanual coordination impairments with bimanual interventions showing benefits. We explored neuroplasticity following hand-arm bimanual intensive therapy (HABIT of 60 hours in twelve CH (6 females, mean age 11 ± 3.6 y. Serial behavioral evaluations and MR imaging including diffusion tensor (DTI and functional (fMRI imaging were performed before, immediately after, and at 6-week follow-up. Manual skills were assessed repeatedly with the Assisting Hand Assessment, Children’s Hand Experience Questionnaire, and Jebsen-Taylor Test of Hand Function. Beta values, indicating the level of activation, and lateralization index (LI, indicating the pattern of brain activation, were computed from fMRI. White matter integrity of major fibers was assessed using DTI. 11/12 children showed improvement after intervention in at least one measure, with 8/12 improving on two or more tests. Changes were retained in 6/8 children at follow-up. Beta activation in the affected hemisphere increased at follow-up, and LI increased both after intervention and at follow-up. Correlations between LI and motor function emerged after intervention. Increased white matter integrity was detected in the corpus callosum and corticospinal tract after intervention in about half of the participants. Results provide first evidence for neuroplasticity changes following bimanual intervention in CH.

  14. Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence.

    Science.gov (United States)

    Weinstein, Maya; Myers, Vicki; Green, Dido; Schertz, Mitchell; Shiran, Shelly I; Geva, Ronny; Artzi, Moran; Gordon, Andrew M; Fattal-Valevski, Aviva; Ben Bashat, Dafna

    2015-01-01

    Neuroplasticity studies examining children with hemiparesis (CH) have focused predominantly on unilateral interventions. CH also have bimanual coordination impairments with bimanual interventions showing benefits. We explored neuroplasticity following hand-arm bimanual intensive therapy (HABIT) of 60 hours in twelve CH (6 females, mean age 11 ± 3.6 y). Serial behavioral evaluations and MR imaging including diffusion tensor (DTI) and functional (fMRI) imaging were performed before, immediately after, and at 6-week follow-up. Manual skills were assessed repeatedly with the Assisting Hand Assessment, Children's Hand Experience Questionnaire, and Jebsen-Taylor Test of Hand Function. Beta values, indicating the level of activation, and lateralization index (LI), indicating the pattern of brain activation, were computed from fMRI. White matter integrity of major fibers was assessed using DTI. 11/12 children showed improvement after intervention in at least one measure, with 8/12 improving on two or more tests. Changes were retained in 6/8 children at follow-up. Beta activation in the affected hemisphere increased at follow-up, and LI increased both after intervention and at follow-up. Correlations between LI and motor function emerged after intervention. Increased white matter integrity was detected in the corpus callosum and corticospinal tract after intervention in about half of the participants. Results provide first evidence for neuroplasticity changes following bimanual intervention in CH.

  15. Precursors to natural grammar learning: preliminary evidence from 4-month-old infants.

    Science.gov (United States)

    Friederici, Angela D; Mueller, Jutta L; Oberecker, Regine

    2011-03-22

    When learning a new language, grammar--although difficult--is very important, as grammatical rules determine the relations between the words in a sentence. There is evidence that very young infants can detect rules determining the relation between neighbouring syllables in short syllable sequences. A critical feature of all natural languages, however, is that many grammatical rules concern the dependency relation between non-neighbouring words or elements in a sentence i.e. between an auxiliary and verb inflection as in is singing. Thus, the issue of when and how children begin to recognize such non-adjacent dependencies is fundamental to our understanding of language acquisition. Here, we use brain potential measures to demonstrate that the ability to recognize dependencies between non-adjacent elements in a novel natural language is observable by the age of 4 months. Brain responses indicate that 4-month-old German infants discriminate between grammatical and ungrammatical dependencies in auditorily presented Italian sentences after only brief exposure to correct sentences of the same type. As the grammatical dependencies are realized by phonologically distinct syllables the present data most likely reflect phonologically based implicit learning mechanisms which can serve as a precursor to later grammar learning.

  16. Precursors to natural grammar learning: preliminary evidence from 4-month-old infants.

    Directory of Open Access Journals (Sweden)

    Angela D Friederici

    Full Text Available When learning a new language, grammar--although difficult--is very important, as grammatical rules determine the relations between the words in a sentence. There is evidence that very young infants can detect rules determining the relation between neighbouring syllables in short syllable sequences. A critical feature of all natural languages, however, is that many grammatical rules concern the dependency relation between non-neighbouring words or elements in a sentence i.e. between an auxiliary and verb inflection as in is singing. Thus, the issue of when and how children begin to recognize such non-adjacent dependencies is fundamental to our understanding of language acquisition. Here, we use brain potential measures to demonstrate that the ability to recognize dependencies between non-adjacent elements in a novel natural language is observable by the age of 4 months. Brain responses indicate that 4-month-old German infants discriminate between grammatical and ungrammatical dependencies in auditorily presented Italian sentences after only brief exposure to correct sentences of the same type. As the grammatical dependencies are realized by phonologically distinct syllables the present data most likely reflect phonologically based implicit learning mechanisms which can serve as a precursor to later grammar learning.

  17. Preliminary evidence for a role of the adrenergic nervous system in generalized anxiety disorder.

    Science.gov (United States)

    Zhang, Xiaobin; Norton, Joanna; Carrière, Isabelle; Ritchie, Karen; Chaudieu, Isabelle; Ryan, Joanne; Ancelin, Marie-Laure

    2017-02-15

    Generalized anxiety disorder (GAD) is a common chronic condition that is understudied compared to other psychiatric disorders. An altered adrenergic function has been reported in GAD, however direct evidence for genetic susceptibility is missing. This study evaluated the associations of gene variants in adrenergic receptors (ADRs) with GAD, with the involvement of stressful events. Data were obtained from 844 French community-dwelling elderly aged 65 or over. Anxiety disorders were assessed using the Mini-International Neuropsychiatry Interview, according to DSM-IV criteria. Eight single-nucleotide polymorphisms (SNPs) involved with adrenergic function were genotyped; adrenergic receptors alpha(1A) (ADRA1A), alpha(2A) (ADRA2A), and beta2 (ADRB2) and transcription factor TCF7L2. Questionnaires evaluated recent stressful life events as well as early environment during childhood and adolescence. Using multivariate logistic regression analyses four SNPs were significantly associated with GAD. A 4-fold modified risk was found with ADRA1A rs17426222 and rs573514, and ADRB2 rs1042713 which remained significant after Bonferroni correction. Certain variants may moderate the effect of adverse life events on the risk of GAD. Replication in larger samples is needed due to the small case number. This is the first study showing that ADR variants are susceptibility factors for GAD, further highlighting the critical role of the adrenergic nervous system in this disorder.

  18. Preliminary evidence for obesity-associated insulin resistance in adolescents without elevations of inflammatory cytokines

    Directory of Open Access Journals (Sweden)

    Cohen Jessica I

    2012-06-01

    Full Text Available Abstract Background To ascertain whether the associations between obesity, inflammation, and insulin resistance established in human adult studies are found among adolescents. Methods We contrasted 36 obese and 24 lean youth on fasting glucose, insulin levels, lipid profile, hemoglobin A1C, markers of hepatic function, white blood cell count, C-reactive protein (CRP and fibrinogen levels. The cytokines IL-6, TNF-α, IFN-γ, IL-10 and IL-4 and the adipokines leptin, resistin, and adiponectin were also compared between the two groups. The fasting glucose and insulin values were used to estimate the degree of insulin resistance with the homeostatic model assessment of insulin resistance (HOMA-IR. T-tests and correlations were run to examine group differences and associations between groups. In addition, regression analyses were used to ascertain whether the markers of inflammation were predictive of the degree of insulin resistance. Results Although obese adolescents had clear evidence of insulin resistance, only CRP, fibrinogen and leptin were elevated; there were no group differences in pro- or anti-inflammatory cytokines nor adiponectin and resistin. Anthropometric measures of obesity and level of insulin resistance were highly correlated to the acute phase reactants CRP and fibrinogen; however, the degree of insulin resistance was not predicted by the pro- or anti-inflammatory cytokine markers. Obese adolescents had higher white blood cell counts. In addition they had higher circulating alanine aminotransferase concentrations and lower circulating albumin and total protein than lean adolescents, possibly as a result of hepatocyte damage from fatty liver. Conclusion Unlike rodent or adult studies, we found that wide-spread systemic inflammation is not necessarily associated with insulin resistance among adolescents. This finding does not support the current paradigm that the associations between obesity and insulin resistance are, to a

  19. Metacognitive training for patients with schizophrenia: preliminary evidence for a targeted, single-module programme.

    Science.gov (United States)

    Balzan, Ryan P; Delfabbro, Paul H; Galletly, Cherrie A; Woodward, Todd S

    2014-12-01

    Metacognitive training is an eight-module, group-based treatment programme for people with schizophrenia that targets the cognitive biases (i.e. problematic thinking styles) thought to contribute to the genesis and maintenance of delusions. The present article is an investigation into the efficacy of a shorter, more targeted, single-module metacognitive training programme, administered individually, which focuses specifically on improving cognitive biases that are thought to be driven by a 'hypersalience of evidence-hypothesis matches' mechanism (e.g. jumping to conclusions, belief inflexibility, reasoning heuristics, illusions of control). It was hypothesised that a more targeted metacognitive training module could still improve performance on these bias tasks and reduce delusional ideation, while improving insight and quality of life. A sample of 28 patients diagnosed with schizophrenia and mild delusions either participated in the hour-long, single-session, targeted metacognitive training programme (n = 14), or continued treatment as usual (n = 14). All patients were assessed using clinical measures gauging overall positive symptomology, delusional ideation, quality of life and insight, and completed two cognitive bias tasks designed to elucidate the representativeness and illusion of control biases. After a 2-week, post-treatment interval, targeted metacognitive training patients exhibited significant decreases in delusional severity and conviction, significantly improved clinical insight, and significant improvements on the cognitive bias tasks, relative to the treatment-as-usual controls. Performance improvements on the cognitive bias tasks significantly correlated with the observed reductions in overall positive symptomology. Patients also evaluated the training positively. Although interpretations of these results are limited due to the lack of an optimally designed, randomised controlled trial and a small sample size, the results are promising and warrant

  20. Preliminary Evidence for the Impact of Combat Experiences on Gray Matter Volume of the Posterior Insula

    Directory of Open Access Journals (Sweden)

    Ashley N. Clausen

    2017-12-01

    Full Text Available Background: Combat-exposed veteran populations are at an increased risk for developing cardiovascular disease. The anterior cingulate cortex (ACC and insula have been implicated in both autonomic arousal to emotional stressors and homeostatic processes, which may contribute to cardiovascular dysfunction in combat veteran populations. The aim of the present study was to explore the intersecting relationships of combat experiences, rostral ACC and posterior insula volume, and cardiovascular health in a sample of combat veterans.Method: Twenty-four male combat veterans completed clinical assessment of combat experiences and posttraumatic stress symptoms. Subjects completed a magnetic resonance imaging scan and autosegmentation using FreeSurfer was used to estimate regional gray matter volume (controlling for total gray matter volume of the rostral ACC and posterior insula. Flow-mediated dilation (FMD was conducted to assess cardiovascular health. Theil-sen robust regressions and Welch's analysis of variance were used to examine relationships of combat experiences and PTSD symptomology with (1 FMD and (2 regional gray matter volume.Results: Increased combat experiences, deployment duration, and multiple deployments were related to smaller posterior insula volume. Combat experiences were marginally associated with poorer cardiovascular health. However, cardiovascular health was not related to rostral ACC or posterior insula volume.Conclusion: The present study provides initial evidence for the relationships of combat experiences, deployment duration, and multiple deployments with smaller posterior insula volume. Results may suggest that veterans with increased combat experiences may exhibit more dysfunction regulating the autonomic nervous system, a key function of the posterior insula. However, the relationship between combat and cardiovascular health was not mediated by regional brain volume. Future research is warranted to further clarify the

  1. Preliminary evidence of sex differences in behavioral and neural responses to palatable food reward in rats.

    Science.gov (United States)

    Sinclair, Elaine B; Hildebrandt, Britny A; Culbert, Kristen M; Klump, Kelly L; Sisk, Cheryl L

    2017-07-01

    The female bias in eating disorder prevalence is the largest in all of psychiatry. Binge eating on palatable food (PF) is a core, maladaptive symptom that cuts across all major types of eating disorders and can be studied via animal models. Using an individual differences rat model of binge eating that identifies binge eating prone (BEP) and binge eating resistant (BER) phenotypes, we previously showed that, compared with males, females consume more PF and are more likely to be classified as BEP. One potential explanation for this sex difference is that PF is inherently more rewarding to females, leading to higher rates of binge eating. Here we tested the hypothesis that females have more robust behavioral and neural responses to PF reward than males. Adult male (N=18) and female (N=17) Sprague-Dawley rats were exposed to the Conditioned Place Preference paradigm using PF as the unconditioned stimulus. Select males (N=9) and females (N=9) were video-recorded during three of the PF-paired conditioning sessions to score feeding behavior. Following CPP, 13 male and 12 female rats were exposed to PF just prior to sacrifice to induce expression of the neural activation marker Fos, and Fos expression was quantified in mesocorticolimbic, hypothalamic, and amygdalar circuits. In the CPP paradigm, females displayed a more robust shift in preference for the chamber paired with PF compared with males, and behavioral analyses revealed that average duration of individual feeding bouts during pairing sessions was longer in females than in males. Fos expression was significantly higher in females vs. males in select regions of the mesocorticolimbic reward circuit, with no sex differences in hypothalamic or amygdalar regions. These results provide initial evidence that PF may be more rewarding to females than to males, possibly due to heightened responsiveness of neural substrates that mediate the hedonic and motivational responses to PF, which in part, may underlie sex

  2. Preliminary evidence that sub-chronic citalopram triggers the re-evaluation of value in intimate partnerships.

    Science.gov (United States)

    Bilderbeck, Amy C; Wakeley, Judi; Godlewska, Beata R; McGlone, Francis; Harris, Tirril; Cowen, Phillip J; Rogers, Robert D

    2014-09-01

    Depression frequently involves disrupted inter-personal relationships, while treatment with serotonergic anti-depressants can interfere with libido and sexual function. However, little is known about how serotonin activity influences appraisals of intimate partnerships. Learning more could help to specify how serotonergic mechanisms mediate social isolation in psychiatric illness. Forty-four healthy heterosexual adults, currently in romantic relationships, received 8 days treatment with the selective serotonin re-uptake inhibitor citalopram (N = 21; 10 male) or placebo (N = 23; 12 male). Participants viewed photographs of unknown, heterosexual couples and made a series of judgements about their relationships. Participants also indicated the importance of relationship features in their own close partnerships, and close partnerships generally. Citalopram reduced the rated quality of couples' physical relationships and the importance attributed to physical and intimate aspects of participants' own relationships. In contrast, citalopram also enhanced the evaluated worth of mutual trust in relationships. Amongst males, citalopram was associated with judgements of reduced turbulence and bickering in others' relationships, and increased male dominance. These data constitute preliminary evidence that enhancing serotonin activity modulates cognitions about sexual activity as part of a re-appraisal of sources of value within close intimate relationships, enhancing the judged importance of longer-term benefits of trust and shared experiences. © The Author (2013). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  3. Prevention of herpes genitalis by the 'Bulgarian' vaccine F.HSV-2V(PRK): preliminary clinical evidence.

    Science.gov (United States)

    Skinner, G R; Davies, J A; Dundarov, S; Andonov, P

    2000-12-01

    To examine the antigenic properties of the formalin-inactivated herpes simplex virus type 2 (HSV-2) virus-particle vaccine F. HSV-2V(PRK), which has been used therapeutically in Bulgaria for 30 years, and to make preliminary assessment of its potential protective efficacy by a follow-up of vaccinated patients with herpes genitalis. Properties of the vaccine were examined by standard immunological laboratory tests. Fifty-five patients at risk of herpes genitalis received 2-4 vaccinations and were monitored during a 6-year follow-up. The vaccine was antigenic in laboratory tests and absorbed neutralizing antibody from hyperimmune rabbit serum against herpes simplex virus type 1 (HSV-1). In vaccinated patients, there was an overall contraction rate of herpes genitalis of 5.4%. There was no evidence of significant local or generalized adverse effects from vaccination. Bulgarian vaccine F.HSV-2V(PRK) may have protective efficacy, which, in association with its apparent safety from our findings and from its clinical use for over 30 years in Bulgaria, suggests that it should be scrutinized by a formal clinical trial.

  4. Preliminary evidence that different mechanisms underlie the anger superiority effect in children with and without Autism Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    Tomoko eIsomura

    2014-05-01

    Full Text Available Previous studies have demonstrated that angry faces capture humans’ attention more rapidly than emotionally positive faces. This phenomenon is referred to as the anger superiority effect (ASE. Despite atypical emotional processing, adults and children with Autism Spectrum Disorders (ASD have been reported to show ASE as well as typically developed (TD individuals. So far, however, few studies have clarified whether or not the mechanisms underlying ASE are the same for both TD and ASD individuals. Here, we tested how TD and ASD children process schematic emotional faces during detection by employing a recognition task in combination with a face-in-the-crowd task. Results of the face-in-the-crowd task revealed the prevalence of ASE both in TD and ASD children. However, the results of the recognition task revealed group differences: In TD children, detection of angry faces required more configural face processing and disrupted the processing of local features. In ASD children, on the other hand, it required more feature-based processing rather than configural processing. Despite the small sample sizes, these findings provide preliminary evidence that children with ASD, in contrast to TD children, show quick detection of angry faces by extracting local features in faces.

  5. Work Rehabilitation Questionnaire (WORQ): development and preliminary psychometric evidence of an ICF-based questionnaire for vocational rehabilitation.

    Science.gov (United States)

    Finger, Monika E; Escorpizo, Reuben; Bostan, Cristina; De Bie, Rob

    2014-09-01

    The International Classification of Functioning, Disability and Health (ICF) has proven to be a valuable framework for vocational rehabilitation (VR). No reliable and valid ICF-based instruments to capture work functioning is known, hence, the aims of this study were: (1) to outline the process for developing an ICF-based questionnaire, the Work Rehabilitation Questionnaire (WORQ) to assess functioning in VR and (2) to report preliminary psychometric evidence. ICF categories were selected from the ICF Core Sets for VR using explorative Rasch-analysis and VR literature review. Questions were worded to assess identified ICF categories. WORQ was translated from English to German. Psychometrics for the German version of WORQ was examined in one VR centre in Switzerland. 44 ICF categories were selected which resulted in 36 questions related to functioning. The psychometric evaluation of WORQ showed high test-retest reliability (Spearman correlation 0.79) (n = 53) and good internal consistency (Cronbachs Alpha 0.88) (n = 74) WORQ showed moderate correlation with Beck Depression Inventory II (Spearman correlation 0.511) and low correlation (Spearman correlation -0.353) with SF-36. WORQ appears to be a reliable, ICF-based questionnaire to evaluate functioning in VR, easy to administer by health or vocational professionals. The additional information gained when using WORQ would contribute to improving interdisciplinary understanding of the patient's situation and therefore support the integrative planning of the return-to-work process or engagement in gainful employment. However, further studies are needed to further examine its use in clinical practice and research, when validated in other patient populations and settings.

  6. Ketamine augmentation for outpatients with treatment-resistant depression: Preliminary evidence for two-step intravenous dose escalation.

    Science.gov (United States)

    Cusin, Cristina; Ionescu, Dawn Flosnik; Pavone, Kara Jean; Akeju, Oluwaseun; Cassano, Paolo; Taylor, Norman; Eikermann, Matthias; Durham, Kelley; Swee, Michaela Ballentyne; Chang, Trina; Dording, Christina; Soskin, David; Kelley, John; Mischoulon, David; Brown, Emery Neal; Fava, Maurizio

    2017-01-01

    Preliminary evidence supports the safety and efficacy of subanesthetic ketamine as an experimental antidepressant, although its effects are often not sustained beyond one week. Studies are lacking that have examined the sustained effects of escalating ketamine doses as augmentation in outpatients with treatment-resistant depression. Therefore, the aims of this study were twofold: (1) to assess the safety and antidepressant efficacy of two-step, repeated-dose ketamine augmentation and (2) to assess the duration of ketamine's antidepressant efficacy as augmentation to ongoing antidepressant pharmacotherapy for 3 months after the final infusion. Fourteen patients with treatment-resistant depression were eligible to receive augmentation with six open-label intravenous ketamine infusions over 3 weeks. For the first three infusions, ketamine was administered at a dose of 0.5 mg/kg over 45 minutes; the dose was increased to 0.75 mg/kg over 45 minutes for the subsequent three infusions. The primary outcome measure was response (as measured on Hamilton Depression Rating Scale-28 items). After the completion of three ketamine infusions, 7.1% (1/14) responded; after all six ketamine infusions, 41.7% (5/12) completers responded and 16.7% (2/12) remitted. Intent-to-treat response and remission rates at the end of the final infusion were 35.7% (5/14) and 14.3% (2/14), respectively. However, all but one responder relapsed within 2 weeks after the final infusion. Repeated, escalating doses of intravenous ketamine augmentation were preliminarily found to be feasible, efficacious and well tolerated. Interaction with concomitant medications and elevated level of treatment resistance are possible factors for non-response.

  7. Evident?

    DEFF Research Database (Denmark)

    Plant, Peter

    2012-01-01

    Quality assurance and evidence in career guidance in Europe are often seen as self-evident approaches, but particular interests lie behind......Quality assurance and evidence in career guidance in Europe are often seen as self-evident approaches, but particular interests lie behind...

  8. Preliminary study of mechanism of action of SN38 derivatives. Physicochemical data, evidence of interaction and alkylation of DNA octamer d(GCGATCGC)2.

    Science.gov (United States)

    Naumczuk, Beata; Kawęcki, Robert; Bocian, Wojciech; Bednarek, Elżbieta; Sitkowski, Jerzy; Kozerski, Lech

    2017-02-01

    The synthesis of water-soluble SN38 derivatives is presented, and their stability in solutions used during drug development studies has been investigated. A preliminary study of mechanism of action of 9-aminomethyl SN38 is presented. Using NMR techniques, the interaction of the oligomer d(GCGATCGC) 2 is studied, showing that the terminal GC base pairs are the main site of interaction. Using pulsed field gradient spin echo and mass spectroscopy, evidence of a spontaneous alkylation reaction of the DNA oligomer with SN38 derivatives is presented. A proposed mechanism of reaction is suggested. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  9. Online Activities for Enhancing Sex Education Curricula: Preliminary Evidence on the Effectiveness of the Abstinence and Contraception Education Storehouse.

    Science.gov (United States)

    Raghupathy, Shobana; Klein, Charles; Card, Josefina

    2013-01-01

    The purpose of this research was to conduct a preliminary evaluation of the Abstinence and Contraception Education Storehouse (ACES), a digital, classroom-based resource designed to supplement existing sex education curricula with highly interactive materials such as video clips, multimedia polls and quizzes, and audiovisual demonstrations. 335 students ages 14-19 were randomly assigned to an ACES-based (treatment) or a standard (control) sex education curriculum. Data were collected at the onset of the intervention and 3-months after the completion of the intervention. Preliminary results were highly encouraging, with ACES participants who were sexually initiated at baseline reporting at the 3-month follow-up significant reductions in the number of times they had sex in the past four weeks. Both sexually initiated and non-sexually initiated youth who experienced the ACES curriculum also demonstrated greater intent to abstain from the sex during the follow-up period than those in the control group.

  10. Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence (DECIDE): protocol and preliminary results

    NARCIS (Netherlands)

    Treweek, Shaun; Oxman, Andrew D.; Alderson, Philip; Bossuyt, Patrick M.; Brandt, Linn; Brożek, Jan; Davoli, Marina; Flottorp, Signe; Harbour, Robin; Hill, Suzanne; Liberati, Alessandro; Liira, Helena; Schünemann, Holger J.; Rosenbaum, Sarah; Thornton, Judith; Vandvik, Per Olav; Alonso-Coello, Pablo; Hartley, Claire; Loudon, Kirsty; Slater, William; Stewart, Neil; Glenton, Claire; Kristiansen, Annette; Lewin, Simon; Moberg, Jenny; Morelli, Angela; Oxman, Andy; Ødgaard-Jensen, Jan; Martinez-García, Laura; Rigau, David; Solà, Ivan; Sanabria, Andrea Juliana; Amato, Laura; Brunetti, Massimo; Magrini, Nicola; Parmelli, Elena; Nonino, Francesco; de Palma, Rossana; Papini, Donato; Pregno, Silvia; Saitto, Carlo; Gopalakrishna, Gowri; Langendam, Miranda; Leeflang, Mariska; Scholten, Rob; Gülmezoglu, Metin; Permanand, Govin; Weerasuriyak, Krisantha; Antes, Gerd; Meerpohl, Jörg; Schünemann, Holger; Alderson, Phil; McFarlane, Emma; Callaghan, Margaret; Graham, Karen; Ritchie, Karen; Service, Duncan; Kunnamo, Ilkka; Guyatt, Gordon; Mustafa, Reem; Neumann, Ignacio; Santesso, Nancy; Spencer, Fred; Falck-Ytter, Yngve; Brignardello-Petersen, Romina; Carrasco- Labra, Alonso; Kunz, Regina; Akl, Elie

    2013-01-01

    Healthcare decision makers face challenges when using guidelines, including understanding the quality of the evidence or the values and preferences upon which recommendations are made, which are often not clear. GRADE is a systematic approach towards assessing the quality of evidence and the

  11. Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence (DECIDE): protocol and preliminary results.

    Science.gov (United States)

    Treweek, Shaun; Oxman, Andrew D; Alderson, Philip; Bossuyt, Patrick M; Brandt, Linn; Brożek, Jan; Davoli, Marina; Flottorp, Signe; Harbour, Robin; Hill, Suzanne; Liberati, Alessandro; Liira, Helena; Schünemann, Holger J; Rosenbaum, Sarah; Thornton, Judith; Vandvik, Per Olav; Alonso-Coello, Pablo

    2013-01-09

    Healthcare decision makers face challenges when using guidelines, including understanding the quality of the evidence or the values and preferences upon which recommendations are made, which are often not clear. GRADE is a systematic approach towards assessing the quality of evidence and the strength of recommendations in healthcare. GRADE also gives advice on how to go from evidence to decisions. It has been developed to address the weaknesses of other grading systems and is now widely used internationally. The Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence (DECIDE) consortium (http://www.decide-collaboration.eu/), which includes members of the GRADE Working Group and other partners, will explore methods to ensure effective communication of evidence-based recommendations targeted at key stakeholders: healthcare professionals, policymakers, and managers, as well as patients and the general public. Surveys and interviews with guideline producers and other stakeholders will explore how presentation of the evidence could be improved to better meet their information needs. We will collect further stakeholder input from advisory groups, via consultations and user testing; this will be done across a wide range of healthcare systems in Europe, North America, and other countries. Targeted communication strategies will be developed, evaluated in randomized trials, refined, and assessed during the development of real guidelines. Results of the DECIDE project will improve the communication of evidence-based healthcare recommendations. Building on the work of the GRADE Working Group, DECIDE will develop and evaluate methods that address communication needs of guideline users. The project will produce strategies for communicating recommendations that have been rigorously evaluated in diverse settings, and it will support the transfer of research into practice in healthcare systems globally.

  12. Preliminary findings of an adapted evidence-based woman-focused HIV intervention on condom use and negotiation among at-risk women in Pretoria, South Africa.

    Science.gov (United States)

    Wechsberg, Wendee M; Luseno, Winnie K; Kline, Tracy L; Browne, Felicia A; Zule, William A

    2010-01-01

    This article presents the results of a randomized trial in South Africa of an adapted evidence-based Woman-Focused intervention on condom use with primary sex partners. The preliminary findings show that regardless of HIV status, condom negotiation was significantly associated with condom use at the 3- and 6-month follow-ups. By intervention group, significant intervention effects were found at 6-month follow-up for HIV-positive and HIV-unknown status women in the Woman-Focused intervention who were more likely than women in the Standard intervention to report condom use with a primary male partner. Among HIV-positive women, those in the Woman-Focused group and those with greater sexual control were more likely to report condom use at the 6-month follow-up. The findings indicate that gender-based interventions for women may result in increased condom negotiation skills.

  13. Prospective Links between Friendship and Early Physical Aggression: Preliminary Evidence Supporting the Role of Friendship Quality through a Dyadic Intervention

    Science.gov (United States)

    Salvas, Marie-Claude; Vitaro, Frank; Brendgen, Mara; Cantin, Ste´phane

    2016-01-01

    Positive friendships have been related to decreasing levels of children's physical aggression over time. While this evidence calls for interventions aimed at helping children build good-quality friendships, tests of causality through experimental manipulations are still needed. The goal of this study was to examine whether an intervention aimed to…

  14. Preliminary Evidence of Reduced Urge to Cough and Cough Response in Four Individuals following Remote Traumatic Brain Injury with Tracheostomy

    Directory of Open Access Journals (Sweden)

    Erin Silverman

    2016-01-01

    Full Text Available Cough and swallow protect the lungs and are frequently impaired following traumatic brain injury (TBI. This project examined cough response to inhaled capsaicin solution challenge in a cohort of four young adults with a history of TBI within the preceding five years. All participants had a history of tracheostomy with subsequent decannulation and dysphagia after their injuries (resolved for all but one participant. Urge to cough (UTC and cough response were measured and compared to an existing database of normative cough response data obtained from 32 healthy controls (HCs. Participants displayed decreased UTC and cough responses compared to HCs. It is unknown if these preliminary results manifest as a consequence of disrupted sensory (afferent projections, an inability to perceive or discriminate cough stimuli, disrupted motor (efferent response, peripheral weakness, or any combination of these factors. Future work should attempt to clarify if the observed phenomena are borne out in a larger sample of individuals with TBI, determine the relative contributions of central versus peripheral nervous system structures to cough sensory perceptual changes following TBI (should they exist, and formulate recommendations for systematic screening and assessment of cough sensory perception in order to facilitate rehabilitative efforts. This project is identified with the National Clinical Trials NCT02240329.

  15. Brain Correlates of Cognitive Remediation in Schizophrenia: Activation Likelihood Analysis Shows Preliminary Evidence of Neural Target Engagement.

    Science.gov (United States)

    Ramsay, Ian S; MacDonald, Angus W

    2015-11-01

    Cognitive remediation training (CRT) for schizophrenia has been found to improve cognitive functioning and influence neural plasticity. However, with various training approaches and mixed findings, the mechanisms driving generalization of cognitive skills from CRT are unclear. In this meta-analysis of extant imaging studies examining CRT's effects, we sought to clarify whether varying approaches to CRT suggest common neural changes and whether such mechanisms are restorative or compensatory. We conducted a literature search to identify studies appropriate for inclusion in an activation likelihood estimation (ALE) meta-analysis. Our criteria required studies to consist of training-based interventions designed to improve patients' cognitive or social functioning, including generalization to untrained circumstances. Studies were also required to examine changes in pre- vs posttraining functional activation using functional magnetic resonance imaging or positron emission tomography. The literature search identified 162 articles, 9 of which were appropriate for inclusion. ALE analyses comparing pre- and posttraining brain activation showed increased activity in the lateral and medial prefrontal cortex (PFC), parietal cortex, insula, and the caudate and thalamus. Notably, activation associated with CRT in the left PFC and thalamus partially overlapped with previous meta-analytically identified areas associated with deficits in working memory, executive control, and facial emotion processing in schizophrenia. We conclude that CRT interventions from varying theoretic modalities elicit plasticity in areas that support cognitive and socioemotional processes in this early set of studies. While preliminary, these changes appear to be both restorative and compensatory, though thalamocortical areas previously associated with dysfunction may be common sources of plasticity for cognitive remediation in schizophrenia. © The Author 2015. Published by Oxford University Press on

  16. Early Life Stress and Macaque Amygdala Hypertrophy: Preliminary Evidence for a Role for the Serotonin Transporter Gene.

    Directory of Open Access Journals (Sweden)

    Jeremy D Coplan

    2014-10-01

    Full Text Available Background: Children exposed to early life stress (ELS exhibit enlarged amygdala volume in comparison to controls. The primary goal of this study was to examine amygdala volumes in bonnet macaques subjected to maternal variable foraging demand (VFD rearing, a well-established model of ELS. Preliminary analyses examined the interaction of ELS and the serotonin transporter gene on amygdala volume. Secondary analyses were conducted to examine the association between amygdala volume and other stress-related variables previously found to distinguish VFD and non-VFD reared animals. Methods: Twelve VFD-reared and nine normally reared monkeys completed MRI scans on a 3T system (mean age=5.2 years. Results: Left amygdala volume was larger in VFD versus control macaques. Larger amygdala volume was associated with: high cerebrospinal fluid concentrations of corticotropin releasing-factor (CRF determined when the animals were in adolescence (mean age=2.7 years; reduced fractional anisotropy of the anterior limb of the internal capsule during young adulthood (mean age=5.2 years and timid anxiety-like responses to an intruder during full adulthood (mean age=8.4 years. Right amygdala volume varied inversely with left hippocampal neurogenesis assessed in late adulthood (mean age=8.7 years. Exploratory analyses also showed a gene-by-environment effect, with VFD-reared macaques with a single short allele of the serotonin transporter gene exhibiting larger amygdala volume compared to VFD-reared subjects with only the long allele and normally reared controls. Conclusion: These data suggest that the left amygdala exhibits hypertrophy after ELS, particularly in association with the serotonin transporter gene, and that amygdala volume variation occurs in concert with other key stress-related behavioral and neurobiological parameters observed across the lifecycle. Future research is required to understand the mechanisms underlying these diverse and persistent changes a

  17. Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr Virus

    Directory of Open Access Journals (Sweden)

    Hickie Ian B

    2006-01-01

    Full Text Available Abstract Background Acute infectious diseases are typically accompanied by non-specific symptoms including fever, malaise, irritability and somnolence that usually resolve on recovery. However, in some individuals these symptoms persist in what is commonly termed post-infective fatigue. The objective of this pilot study was to determine the gene expression correlates of post-infective fatigue following acute Epstein Barr virus (EBV infection. Methods We followed 5 people with acute mononucleosis who developed post-infective fatigue of more than 6 months duration and 5 HLA-matched control subjects who recovered within 3 months. Subjects had peripheral blood mononuclear cell (PBMC samples collected at varying time points including at diagnosis, then every 2 weeks for 3 months, then every 3 months for a year. Total RNA was extracted from the PBMC samples and hybridized to microarrays spotted with 3,800 oligonucleotides. Results Those who developed post-infective fatigue had gene expression profiles indicative of an altered host response during acute mononucleosis compared to those who recovered uneventfully. Several genes including ISG20 (interferon stimulated gene, DNAJB2 (DnaJ [Hsp40] homolog and CD99, CDK8 (cyclin-dependent kinase 8, E2F2 (E2F transcription factor 2, CDK8 (cyclin-dependent kinase 8, and ACTN2 (actinin, alpha 2, known to be regulated during EBV infection, were differentially expressed in post-infective fatigue cases. Several of the differentially expressed genes affect mitochondrial functions including fatty acid metabolism and the cell cycle. Conclusion These preliminary data provide insights into alterations in gene transcripts associated with the varied clinical outcomes from acute infectious mononucleosis.

  18. The molecular evidence of neural plasticity induced by cerebellar repetitive transcranial magnetic stimulation in the rat brain: a preliminary report.

    Science.gov (United States)

    Lee, Seung Ah; Oh, Byung-Mo; Kim, Sang Jeong; Paik, Nam-Jong

    2014-07-11

    Cerebellar repetitive transcranial magnetic stimulation (rTMS) has been applied to treat several pathological conditions with insufficient evidence of molecular mechanism. Neural plasticity is proposed as one of mechanism. This study aimed to (1) confirm the feasibility of focal stimulation over cerebellar cortex and (2) investigate cerebellar rTMS effects on molecular changes associated with neural plasticity in the rat. For feasibility, six male Sprague-Dawley rats underwent (18)F-FDG positron emission tomography (PET) to confirm focal stimulation on the cerebellar cortex after rTMS. For molecular evidence, thirty rats underwent a single (N=15) or 10 sessions (N=15) of rTMS with low-, high-frequency, or sham stimulation. In cerebellar cortex, reverse-transcriptase polymerase chain reaction and western blotting were performed on mRNA and proteins associated with neural plasticity: metabotrophic glutamate receptor 1 (GluR1), 2-amino-5-methyl-4-isoxazole-propionatic acid (AMPA) receptor (GluR2) and protein kinase C (PKC). As a result, (18)F-FDG-PET showed an increase of glucose metabolism in the cerebellar cortex. The transcription of mGluR1 decreased following a single session of high-frequency rTMS. Synthesis of mGluR, PKC and GluR2 was reduced after rTMS, especially high frequency stimulation. It is suggested that rTMS could focus on the cerebellar cortex in the rat and induce neural plasticity associated with long-term depression. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. Decentering the self? Preliminary evidence for changes in self- vs. other related processing as a long-term outcome of loving-kindness meditation

    Directory of Open Access Journals (Sweden)

    Fynn-Mathis Trautwein

    2016-11-01

    Full Text Available AbstractResearch in social neuroscience provides increasing evidence that self and other are interconnected, both on a conceptual and on an affective representational level. Moreover, the ability to recognize the other as ‘like the self’ is thought to be essential for social phenomena like empathy and compassion. Meditation practices such as loving-kindness meditation (LKM have been found to enhance these capacities. Therefore, we investigated whether LKM is associated to an increased integration of self-other-representations. As an indicator, we assessed the P300 event-related potential elicited by oddball stimuli of the self-face and a close other’s face in twelve long-term practitioners of LKM and twelve matched controls. In line with previous studies, the self elicited larger P300 amplitudes than close other. This effect was reduced in the meditation sample at parietal but not frontal midline sites. Within this group, smaller differences between self- and other-related P300 were associated with increasing meditation practice. Across groups, smaller P300 differences correlated with self-reported compassion. In meditators we also investigated the effect of a short LKM compared to a control priming procedure in order to test whether the state induction would additionally modulate self- versus other-related P300. However, no effect of the priming conditions was observed. Overall, our findings provide preliminary evidence that prolonged meditation practice may modulate self- versus other-related processing, accompanied by an increase in compassion. Further evidence is needed, however, to show if this is a direct outcome of loving-kindness meditation.

  20. Preliminary evidence of early bone resorption in a sheep model of acute burn injury: an observational study.

    Science.gov (United States)

    Klein, Gordon L; Xie, Yixia; Qin, Yi-Xian; Lin, Liangjun; Hu, Minyi; Enkhbaatar, Perenlei; Bonewald, Lynda F

    2014-03-01

    Treatment with bisphosphonates within the first 10 days of severe burn injury completely prevents bone loss. We therefore postulated that bone resorption occurs early post burn and is the primary explanation for acute bone loss in these patients. Our objective was to assess bone for histological and biomechanical evidence of early resorption post burn. We designed a randomized controlled study utilizing a sheep model of burn injury. Three sheep received a 40 % total body surface area burn under isoflurane anesthesia, and three other sheep received cotton-smoke inhalation and served as control. Burned sheep were killed 5 days post procedure and controls were killed 2 days post procedure. Backscatter scanning electron microscopy was performed on iliac crests obtained immediately postmortem along with quantitative histomorphometry and compression testing to determine bone strength (Young's modulus). Blood ionized Ca was also determined in the first 24 h post procedure as was urinary CTx. Three of three sheep killed at 5 days had evidence of scalloping of the bone surface, an effect of bone resorption, whereas none of the three sheep killed at 2 days post procedure had scalloping. One of the three burned sheep killed at 5 days showed quantitative doubling of the eroded surface and halving of the bone volume compared to sham controls. Mean values of Young's modulus were approximately one third lower in the burned sheep killed at 5 days compared to controls, p = 0.08 by unpaired t test, suggesting weaker bone. These data suggest early post-burn bone resorption. Urine CTx normalized to creatinine did not differ between groups at 24 h post procedure because the large amounts of fluids received by the burned sheep may have diluted urine creatinine and CTx and because the urine volume produced by the burned sheep was threefold that of the controls. We calculated 24 h urinary CTx excretion, and with this calculation CTx excretion/24 h in the burned sheep was

  1. Forming Entrepreneurial Mindsets? Preliminary Evidence of Teaching Practices from Primary Schools in a Developing Area in South America

    Directory of Open Access Journals (Sweden)

    Maria Auxiliadora N. Figueiredo-Nery

    2008-08-01

    Full Text Available Over the past few years there has been a renewed interest by governments, companies and academics in the role of entrepreneurship in innovation and economic growth. There has also been a proliferation of studies on education for entrepreneurship in industrialised and developing countries. However, by addressing ‘entrepreneurship’ in terms of SMEs and high-tech start-ups, they overlook: (i the blurring distinctions between entrepreneurial and managerial capitalism, (ii an erosion of the Schumpeterian dichotomy between large and small firms, and (iii the growing importance of entrepreneurial management within companies as a source for economic growth. Additionally, ‘entrepreneurship’ tends to be taught as a stand-alone topic in higher education and business/non-business courses. Empirical studies related to entrepreneurship education within primary schools, especially in least developed locations in developing countries, are largely missing in this field. Drawing on first-hand empirical evidence from primary schools in a developing area in South America, this paper examines the incidence and functioning of pedagogic practices potentially related to the initial formation of entrepreneurial mindsets. The findings show that, despite some efforts, the researched schools suffered from, not surprisingly, inadequate physical conditions and, most importantly, teachers’ unawareness and deficient qualification related to the adoption of these techniques. These problems seemed to prevent children from developing important features of their initial entrepreneurial mindsets. Thus, if companies and countries want to secure their sources of revolutionary ideas and continuous and des-continuous innovation, they need to have a long-term commitment to continuously develop and nurture the seeds for their future innovative knowledge bases. Specifically, a comprehensive, long-term, geographically and socially inclusive perspective on entrepreneurship

  2. Promoting Mentalizing in Pupils by Acting on Teachers: Preliminary Italian Evidence of the “Thought in Mind” Project

    Science.gov (United States)

    Valle, Annalisa; Massaro, Davide; Castelli, Ilaria; Sangiuliano Intra, Francesca; Lombardi, Elisabetta; Bracaglia, Edoardo; Marchetti, Antonella

    2016-01-01

    Mentalization research focuses on different aspects of this topic, highlighting individual differences in mentalizing and proposing programs of intervention for children and adults to increase this ability. The “Thought in Mind Project” (TiM Project) provides training targeted to adults—teachers or parents—to increase their mentalization and, consequently, to obtain mentalization improvement in children. The present research aimed to explore for the first time ever the potential of training for teachers based on the TiM Project, regarding the enhancement of mentalizing of an adult who would have interacted as a teacher with children. For this reason, two teachers – similar for meta-cognitive and meta-emotional skills - and their classes (N = 46) were randomly assigned to the training or control condition. In the first case, the teacher participated in training on the implementation of promotion of mentalizing in everyday school teaching strategies; in the second case the teacher participated in a control activity, similar to training for scheduling and methods, but without promoting the implementation of mentalization (in both conditions two meetings lasting about 3 h at the beginning of the school year and two supervisions during the school year were conducted). The children were tested by tasks assessing several aspects of mentalization (second and third-order false belief understanding, Strange Stories, Reading the mind in the Eyes, Mentalizing Task) both before and after the teacher participate in the TiM or control training (i.e., at the beginning and at the end of the school year). The results showed that, although some measured components of mentalization progressed over time, only the TiM Project training group significantly improved in third order false belief understanding and changed - in a greater way compared to the control group – in two of the three components of the Mentalizing Task. These evidences are promising about the idea that the

  3. Promoting Mentalizing in Pupils by Acting on Teachers: Preliminary Italian Evidence of the "Thought in Mind" Project

    Directory of Open Access Journals (Sweden)

    Annalisa Valle

    2016-08-01

    Full Text Available Mentalization research focuses on different aspects of this topic, highlighting individual differences in mentalizing and proposing programs of intervention for children and adults to increase this ability. The Thought in Mind Project (TiM Project provides training targeted to adults―teachers or parents―to increase their mentalization and, consequently, to obtain mentalization improvement in children. The present research aimed to explore for the first time ever the potential of training for teachers based on the TiM Project, regarding the enhancement of mentalizing of an adult who would have interacted as a teacher with children. For this reason, two teachers – similar for meta-cognitive and meta-emotional skills - and their classes (N=46 were randomly assigned to the training or control condition. In the first case, the teacher participated in training on the implementation of promotion of mentalizing in everyday school teaching strategies; in the second case the teacher participated in a control activity, similar to training for scheduling and methods, but without promoting the implementation of mentalization (in both conditions two meetings lasting about three hours at the beginning of the school year and two supervisions during the school year were conducted. The children were tested by tasks assessing several aspects of mentalization (2nd and 3rd order false belief understanding, Strange Stories, Reading the mind in the Eyes, Mentalizing Task both before and after the teacher participate in the TiM or control training (i.e. at the beginning and at the end of the school year. The results showed that, although some measured components of mentalization progressed over time, only the TiM training group significantly improved in 3rd order false belief understanding and changed - in a greater way compared to the control group - in two of the three components of the Mentalizing Task. These evidences are promising about the idea that the

  4. Promoting Mentalizing in Pupils by Acting on Teachers: Preliminary Italian Evidence of the "Thought in Mind" Project.

    Science.gov (United States)

    Valle, Annalisa; Massaro, Davide; Castelli, Ilaria; Sangiuliano Intra, Francesca; Lombardi, Elisabetta; Bracaglia, Edoardo; Marchetti, Antonella

    2016-01-01

    Mentalization research focuses on different aspects of this topic, highlighting individual differences in mentalizing and proposing programs of intervention for children and adults to increase this ability. The "Thought in Mind Project" (TiM Project) provides training targeted to adults-teachers or parents-to increase their mentalization and, consequently, to obtain mentalization improvement in children. The present research aimed to explore for the first time ever the potential of training for teachers based on the TiM Project, regarding the enhancement of mentalizing of an adult who would have interacted as a teacher with children. For this reason, two teachers - similar for meta-cognitive and meta-emotional skills - and their classes (N = 46) were randomly assigned to the training or control condition. In the first case, the teacher participated in training on the implementation of promotion of mentalizing in everyday school teaching strategies; in the second case the teacher participated in a control activity, similar to training for scheduling and methods, but without promoting the implementation of mentalization (in both conditions two meetings lasting about 3 h at the beginning of the school year and two supervisions during the school year were conducted). The children were tested by tasks assessing several aspects of mentalization (second and third-order false belief understanding, Strange Stories, Reading the mind in the Eyes, Mentalizing Task) both before and after the teacher participate in the TiM or control training (i.e., at the beginning and at the end of the school year). The results showed that, although some measured components of mentalization progressed over time, only the TiM Project training group significantly improved in third order false belief understanding and changed - in a greater way compared to the control group - in two of the three components of the Mentalizing Task. These evidences are promising about the idea that the creation of

  5. Safety and preliminary evidence of biologic efficacy of a mammaglobin-a DNA vaccine in patients with stable metastatic breast cancer.

    Science.gov (United States)

    Tiriveedhi, Venkataswarup; Tucker, Natalia; Herndon, John; Li, Lijin; Sturmoski, Mark; Ellis, Matthew; Ma, Cynthia; Naughton, Michael; Lockhart, A Craig; Gao, Feng; Fleming, Timothy; Goedegebuure, Peter; Mohanakumar, Thalachallour; Gillanders, William E

    2014-12-01

    Mammaglobin-A (MAM-A) is overexpressed in 40% to 80% of primary breast cancers. We initiated a phase I clinical trial of a MAM-A DNA vaccine to evaluate its safety and biologic efficacy. Patients with breast cancer with stable metastatic disease were eligible for enrollment. Safety was monitored with clinical and laboratory assessments. The CD8 T-cell response was measured by ELISPOT, flow cytometry, and cytotoxicity assays. Progression-free survival (PFS) was described using the Kaplan-Meier product limit estimator. Fourteen subjects have been treated with the MAM-A DNA vaccine and no significant adverse events have been observed. Eight of 14 subjects were HLA-A2(+), and the CD8 T-cell response to vaccination was studied in detail. Flow cytometry demonstrated a significant increase in the frequency of MAM-A-specific CD8 T cells after vaccination (0.9% ± 0.5% vs. 3.8% ± 1.2%; P cells (41 ± 32 vs. 215 ± 67 spm; P cell responses, and preliminary evidence suggests improved PFS. Additional studies are required to define the potential of the MAM-A DNA vaccine for breast cancer prevention and/or therapy. ©2014 American Association for Cancer Research.

  6. Preliminary Evidence for the Emergence of a Health Care Online Community of Practice: Using a Netnographic Framework for Twitter Hashtag Analytics.

    Science.gov (United States)

    Roland, Damian; Spurr, Jesse; Cabrera, Daniel

    2017-07-14

    Online communities of practice (oCoPs) may emerge from interactions on social media. These communities offer an open digital space and flat role hierarchy for information sharing and provide a strong group identity, rapid flow of information, content curation, and knowledge translation. To date, there is only a small body of evidence in medicine or health care to verify the existence of an oCoP. We aimed to examine the emergence of an oCoP through the study of social media interactions of the free open access medical education (FOAM) movement. We examined social media activity in Twitter by analyzing the network centrality metrics of tweets with the #FOAMed hashtag and compared them with previously validated criteria of a community of practice (CoP). The centrality analytics of the FOAM community showed concordance with aspects of a general CoP (in terms of community, domain, and practice), as well as some specific traits of a health care community, including social control, common purpose, flat hierarchy, and network-based and concrete achievement. This study demonstrated preliminary evidence of an oCoP focused on education and based on social media interactions. Further examination of the topology of the network is needed to definitely prove the existence of an oCoP. Given that these communities result in significant knowledge translation and practice change, further research in this area appears warranted. ©Damian Roland, Jesse Spurr, Daniel Cabrera. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.07.2017.

  7. Recognition of the Kaweka Terrane in northern South Island, New Zealand : preliminary evidence from Rb-Sr metamorphic and U-Pb detrital zircon ages

    International Nuclear Information System (INIS)

    Adams, C.J.; Mortimer, N.; Campbell, H.J.; Griffin, W.L.

    2011-01-01

    Detrital zircon U-Pb ages and Rb-Sr metamorphic ages from low-grade Torlesse Supergroup metasedimentary rocks from North Canterbury and Marlborough provide preliminary evidence for a continuation of the Kaweka Terrane of the central North Island into the Torlesse Composite Terrane of the South Island. This would extend from the south side of the Wairau Fault in the upper Wairau River valley southwards to the Lake Tennyson and Lake Sumner areas, and as far as Hawarden. Rb-Sr ages indicate Jurassic metamorphism, 170±24 Ma, with initial 87 Sr/ 86 Sr ratios at that time 0.7073 ± 0.0007 i.e. similar to their North Island counterparts. These Kaweka Terrane rocks have detrital zircon ages that follow the distinctive pattern of the Torlesse rocks in general, i.e. substantial (>30%) Permian-Triassic and Precambrian-Early Palaeozoic groupings, but they also have minor youngest age components c. 175-165 Ma which constrain a maximum Early-Middle Jurassic depositional age. In detail, significant, older zircon components are Late Permian-Early Triassic (260-240 Ma) and Late Triassic (220-210 Ma), but the Precambrian-Early Palaeozoic detrital zircon ages are more scattered. The Kaweka Terrane thus forms a linear belt (c. 500 km) along the length of the Torlesse Composite Terrane in both North and South Islands. In the South Island it coincides with the Esk Head Belt, i.e. east of the Rakaia Terrane (Triassic-Late Permian) and west of the Pahau Terrane (Early Cretaceous-Late Jurassic). (author). 61 refs., 4 figs., 2 tabs.

  8. Habitual pelvic posture and time spent sitting: Measurement test-retest reliability for the LUMOback device and preliminary evidence for slouched posture in individuals with low back pain.

    Science.gov (United States)

    Takasaki, Hiroshi

    2017-01-01

    It has been difficult to monitor the pelvic position during actual daily life. However, recent developments in wearable device technologies, such as the LUMOback device, provide the possibility to evaluate habitual pelvic posture and time spent sitting during daily life. The current study aimed (1) to investigate test-retest reliability for habitual pelvic posture and time spent sitting with the LUMOback in individuals with prolonged low back pain (low back pain group) and without low back pain (control group), and (2) to preliminarily investigate differences in those measures between groups. Fifteen individuals in each group wore the LUMOback daily for 2 weeks. Intraclass correlation coefficients were calculated in each group by comparing the mean from the first week with the mean from the second week: (1) for the posture score, which is a proportion of time with neutral posture, and (2) for time spent sitting. The two measures for the first week were compared between the low back pain and control groups. The intraclass correlation coefficients for the posture score were .82 in the low back pain group and .91 in the control group. The intraclass correlation coefficients for time spent sitting were .75 in the low back pain group and .85 in the control group. The posture score in the low back pain group (mean ± SD: 37.5% ± 10.3%) was less than that in the control group (49.6% ± 6.0%; p  .05). The current study found (1) acceptable test-retest reliability for the posture score and time spent sitting evaluated by the LUMOback device, and (2) preliminary evidence of a difference in the posture score, indicating a more slouched lumbopelvic posture in individuals with prolonged low back pain than those without low back pain.

  9. Habitual pelvic posture and time spent sitting: Measurement test–retest reliability for the LUMOback device and preliminary evidence for slouched posture in individuals with low back pain

    Science.gov (United States)

    Takasaki, Hiroshi

    2017-01-01

    Objectives: It has been difficult to monitor the pelvic position during actual daily life. However, recent developments in wearable device technologies, such as the LUMOback device, provide the possibility to evaluate habitual pelvic posture and time spent sitting during daily life. The current study aimed (1) to investigate test–retest reliability for habitual pelvic posture and time spent sitting with the LUMOback in individuals with prolonged low back pain (low back pain group) and without low back pain (control group), and (2) to preliminarily investigate differences in those measures between groups. Methods: Fifteen individuals in each group wore the LUMOback daily for 2 weeks. Intraclass correlation coefficients were calculated in each group by comparing the mean from the first week with the mean from the second week: (1) for the posture score, which is a proportion of time with neutral posture, and (2) for time spent sitting. The two measures for the first week were compared between the low back pain and control groups. Results: The intraclass correlation coefficients for the posture score were .82 in the low back pain group and .91 in the control group. The intraclass correlation coefficients for time spent sitting were .75 in the low back pain group and .85 in the control group. The posture score in the low back pain group (mean ± SD: 37.5% ± 10.3%) was less than that in the control group (49.6% ± 6.0%; p  .05). Conclusions: The current study found (1) acceptable test–retest reliability for the posture score and time spent sitting evaluated by the LUMOback device, and (2) preliminary evidence of a difference in the posture score, indicating a more slouched lumbopelvic posture in individuals with prolonged low back pain than those without low back pain. PMID:28951781

  10. Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer's disease: a pilot randomized controlled trial.

    Science.gov (United States)

    Suttanon, Plaiwan; Hill, Keith D; Said, Catherine M; Williams, Susan B; Byrne, Karin N; LoGiudice, Dina; Lautenschlager, Nicola T; Dodd, Karen J

    2013-05-01

    To evaluate the feasibility and safety of a home-based exercise programme for people with Alzheimer's disease, and to provide preliminary evidence of programme effectiveness in improving balance and mobility and reducing falls risk. A randomized controlled trial. Community. Forty people with mild to moderate Alzheimer's disease (mean age 81.9, SD 5.72; 62.5% female). Participants were randomized to a six-month home-based individually tailored balance, strengthening and walking exercise programme (physiotherapist) or a six-month home-based education programme (control) (occupational therapist). Both programmes provided six home-visits and five follow-up phone calls. Balance, mobility, falls and falls risk were measured at baseline and programme completion. Intention-to-treat analysis using a generalized linear model with group allocation as a predictor variable was performed to evaluate programme effectiveness. Feasibility and adverse events were systematically recorded at each contact. Fifty-eight per cent of the exercise group finished the programme, completing an average of 83% of prescribed sessions, with no adverse events reported. Functional Reach improved significantly (P = 0.002) in the exercise group (mean (SD), 2.28 (4.36)) compared to the control group (-2.99 (4.87)). Significant improvement was also observed for the Falls Risk for Older People - Community score (P = 0.008) and trends for improvement on several other balance, mobility, falls and falls risk measures for the exercise group compared to the control group. The exercise programme was feasible and safe and may help improve balance and mobility performance and reduce falls risk in people with Alzheimer's disease.

  11. Mechanical diagnosis and therapy enhances attitude toward self-management in people with musculoskeletal disorders: A preliminary evidence with a before-after design.

    Science.gov (United States)

    Takasaki, Hiroshi

    2017-01-01

    -management programs in previous studies (%> positive "reliable change': Self-monitoring and Insight = 20.5%, Skill and Technique Acquisition = 30.7%; % net positive "reliable change": Self-monitoring and Insight = 14.1%, Skill and Technique Acquisition = 23.0%). This study provides a preliminary evidence that mechanical diagnosis and therapy enhances patient's self-management skills, particularly in the self-monitoring skills for symptoms/functions and the self-management skill for symptoms/problems.

  12. Memory-Focused Cognitive Therapy for Cocaine Use Disorder: Theory, Procedures and Preliminary Evidence From an External Pilot Randomised Controlled Trial

    Directory of Open Access Journals (Sweden)

    John Marsden

    2018-03-01

    of regular cocaine use, baseline outcome score, and group estimated the effectiveness of the intervention. The trial is registered with the ISCRTN (ISRCTN16462783. Findings: Between July 15, 2015, and November 27, 2016, 58 patients were assessed for eligibility and 30 participants were randomised (14 to the control group and 16 to the intervention. With outcome data collected for all participants at the endpoint, the intervention group mean CEQ-F score (14·77; SD 21·47 was lower than the control group mean (51·75; SD 22·72; ES -1·62; 95% CI -2·45 to −0·80.MFCT was associated with more cocaine abstinence in the intervention group (PDA 85·94; SD 18·96 than the control group (PDA 54·59; SD 30·29; ES 1·19; 90% CI 0·54 to 1·84. There was also greater maximum abstinence in the intervention group (LPA 15·69; SD 10·10 than the control group (6·00; SD 7·36; ES 1·06; 90% CI 0·41 to 1·70. Exploratory, confounder-adjusted regression models for this preliminary effect supported the treatment association for reduced craving experiences (CEQ-F Coef. -28·25; 95% CI -45·15 to −11·35; more abstinence (PDA Incidence Rate Ratio [IRR] 1·56; 95% CI 1·31 to 1·88; and greater maximum abstinence (LPA IRR 2·56; 95% CI 1·96 to 3·35, although relative weak unmeasured confounding could overturn these model-adjusted exposure-outcome associations.There were four serious adverse events (among three participants. None were judged related to study procedures or interventions. Interpretation: In this first external pilot randomised controlled trial of MFCT for CUD, we have shown that the intervention and control procedures and acceptable feasible and safe, and report preliminary evidence that MFCT is associated with reduced craving and increased abstinence. These findings support progression to a substantive trial. Funding Source: UK National Institute for Health Research, Biomedical Research Centre. Keywords: Cocaine, Craving, Memory, Reconsolidation, Cognitive

  13. Preliminary evidence for association of genetic variants in pri-miR-34b/c and abnormal miR-34c expression with attention deficit and hyperactivity disorder.

    Science.gov (United States)

    Garcia-Martínez, I; Sánchez-Mora, C; Pagerols, M; Richarte, V; Corrales, M; Fadeuilhe, C; Cormand, B; Casas, M; Ramos-Quiroga, J A; Ribasés, M

    2016-08-30

    Attention deficit and hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by impairment to sustain attention and inability to control impulses and activity level. The etiology of ADHD is complex, with an estimated heritability of 70-80%. Under the hypothesis that alterations in the processing or target binding of microRNAs (miRNAs) may result in functional alterations predisposing to ADHD, we explored whether common polymorphisms potentially affecting miRNA-mediated regulation are involved in this psychiatric disorder. We performed a comprehensive association study focused on 134 miRNAs in 754 ADHD subjects and 766 controls and found association between the miR-34b/c locus and ADHD. Subsequently, we provided preliminary evidence for overexpression of the miR-34c-3p mature form in peripheral blood mononuclear cells of ADHD subjects. Next, we tested the effect on gene expression of single-nucleotide polymorphisms within the ADHD-associated region and found that rs4938923 in the promoter of the pri-miR-34b/c tags cis expression quantitative trait loci for both miR-34b and miR-34c and has an impact on the expression levels of 681 transcripts in trans, including genes previously associated with ADHD. This gene set was enriched for miR-34b/c binding sites, functional categories related to the central nervous system, such as axon guidance or neuron differentiation, and serotonin biosynthesis and signaling canonical pathways. Our results provide preliminary evidence for the contribution to ADHD of a functional variant in the pri-miR-34b/c promoter, possibly through dysregulation of the expression of mature forms of miR-34b and miR-34c and some target genes. These data highlight the importance of abnormal miRNA function as a potential epigenetic mechanism contributing to ADHD.

  14. Preliminary Evidence of the Effects of High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Swallowing Functions in Post-Stroke Individuals with Chronic Dysphagia

    Science.gov (United States)

    Cheng, Ivy K. Y.; Chan, Karen M. K.; Wong, C. S.; Cheung, Raymond T. F.

    2015-01-01

    Background: There is growing evidence of potential benefits of repetitive transcranial magnetic stimulation (rTMS) in the rehabilitation of dysphagia. However, the site and frequency of stimulation for optimal effects are not clear. Aims: The aim of this pilot study is to investigate the short-term effects of high-frequency 5 Hz rTMS applied to…

  15. Preliminary Evidence Assessing Social-Emotional Competences in Deaf and Hard of Hearing Infants and Toddlers Using a New Parent Questionnaire.

    Science.gov (United States)

    Hintermair, Manfred; Sarimski, Klaus; Lang, Markus

    2017-04-01

    Social-emotional competences are an important developmental domain for deaf and hard of hearing (DHH) children and early diagnosis of problems is needed to ensure that DHH children receive appropriate support in this domain. In order to explore the usefulness of an instrument, which was recently developed for very young children, two studies in DHH infants and toddlers were conducted from Germany using the Social-Emotional Assessment/Evaluation Measure (Squires et al. (2013). Social-Emotional Assessment/Evaluation Measure (SEAM). Baltimore, ML: Brooks). Preliminary analysis of data obtained from a sample of 182 DHH children aged between 2 and 36 months (Study 1) suggests that it provides valid, reliable data and is suitable for use in practice. The data also corroborate well-known findings from other research in deaf education, in particular the role of parental responsivity for the development of social-emotional competences. Study 2 documents the consistency of evaluations of 44 DHH children by their mothers and by early intervention providers using the scales. Overall, the results suggest that this new evaluation instrument has potential applications in deaf educational practice but further research is needed to demonstrate its full value. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. Preliminary evidence for reduced preoperative cerebral blood flow velocity as a risk factor for cognitive decline three months after cardiac surgery: an extension study.

    Science.gov (United States)

    Messerotti Benvenuti, S; Zanatta, P; Valfrè, C; Polesel, E; Palomba, D

    2012-11-01

    This extension study investigated the association between preoperative cerebral blood flow (CBF) velocity and postoperative cognitive decline (POCD) at a three-month follow-up in patients who underwent cardiac surgery. Continuous transcranial Doppler ultrasound on both middle cerebral arteries (MCAs) was used preoperatively in 31 right-handed cardiac surgery patients at rest. Each patient performed a neuropsychological evaluation to assess cognitive performance before surgery, at discharge and at three-month follow-up. Patients with POCD at the three-month follow-up had a marginally significantly lower preoperative CBF velocity in the left MCA than patients without POCD. Moreover, the group with POCD had a significantly lower CBF velocity in the left than in the right MCA, whereas no difference between the left and right CBF velocity was found in the group without POCD. These preliminary findings suggest that reduced preoperative CBF velocity in the left MCA may represent an independent risk factor for cognitive decline in patients three months after surgery.

  17. Paleopathological evidence of the cranial remains from the Sima de los Huesos Middle Pleistocene site (Sierra de Atapuerca, Spain). Description and preliminary inferences.

    Science.gov (United States)

    Pérez, P J; Gracía, A; Martínez, I; Arsuaga, J L

    1997-01-01

    The large Sima de los Huesos sample provides for the first time the opportunity of performing a paleopathological study of a Middle Pleistocene population. A high frequency of bilateral temporomandibular arthropathy has been observed. We found an ear hyperostosis in Cranium 4, that probably caused deafness that we consider to be of infectious origin. Three osteomata were found in the cranial collection. One severe trauma was evident on the left supraorbital torus of an immature individual. Many cranial vault erosions, mostly restricted to the external table, are found in the sample. Cranium 5 displays thirteen of these. Cranium 5 also shows an extensive maxillary osteitis associated with a dental apical abscess, as well as another dental apical abscess in its mandible. Most of the adult frontal bones show a worm-like pattern of vascular channelling in the orbital roof, also found in modern populations.

  18. Likelihood ratio-based differentiation of nodular Hashimoto thyroiditis and papillary thyroid carcinoma in patients with sonographically evident diffuse hashimoto thyroiditis: preliminary study.

    Science.gov (United States)

    Wang, Liang; Xia, Yu; Jiang, Yu-Xin; Dai, Qing; Li, Xiao-Yi

    2012-11-01

    To assess the efficacy of sonography for discriminating nodular Hashimoto thyroiditis from papillary thyroid carcinoma in patients with sonographically evident diffuse Hashimoto thyroiditis. This study included 20 patients with 24 surgically confirmed Hashimoto thyroiditis nodules and 40 patients with 40 papillary thyroid carcinoma nodules; all had sonographically evident diffuse Hashimoto thyroiditis. A retrospective review of the sonograms was performed, and significant benign and malignant sonographic features were selected by univariate and multivariate analyses. The combined likelihood ratio was calculated as the product of each feature's likelihood ratio for papillary thyroid carcinoma. We compared the abilities of the original sonographic features and combined likelihood ratios in diagnosing nodular Hashimoto thyroiditis and papillary thyroid carcinoma by their sensitivity, specificity, and Youden index. The diagnostic capabilities of the sonographic features varied greatly, with Youden indices ranging from 0.175 to 0.700. Compared with single features, combinations of features were unable to improve the Youden indices effectively because the sensitivity and specificity usually changed in opposite directions. For combined likelihood ratios, however, the sensitivity improved greatly without an obvious reduction in specificity, which resulted in the maximum Youden index (0.825). With a combined likelihood ratio greater than 7.00 as the diagnostic criterion for papillary thyroid carcinoma, sensitivity reached 82.5%, whereas specificity remained at 100.0%. With a combined likelihood ratio less than 1.00 for nodular Hashimoto thyroiditis, sensitivity and specificity were 90.0% and 92.5%, respectively. Several sonographic features of nodular Hashimoto thyroiditis and papillary thyroid carcinoma in a background of diffuse Hashimoto thyroiditis were significantly different. The combined likelihood ratio may be superior to original sonographic features for

  19. Characterizing slab inputs in the earliest stages of subduction: Preliminary evidence from fluid-mobile element systematics for IODP Expedition 352 recovered volcanic samples

    Science.gov (United States)

    Sanatan, Keir; Ryan, Jeffrey; Atlas, Zachary; Reagan, Mark

    2016-04-01

    IODP Expedition 352 recovered ~1.22 km of boninitic and basaltic volcanic rocks from four sites in the Izu-Bonin forearc to examine the volcanic phenomena associated with subduction initiation. While the recovered forearc basalts give little indication for the involvement of slab-derived volatiles, the extensive sequences of boninite series lavas recovered up-section show physical evidence for extensive fluid involvement (heavy vesicularity, explosive eruptive style), along with chemistries indicative of fluid-addition melting of depleted mantle sources. We are attempting to assay the makeup and likely slab provenance of these fluids via their fluid-mobile element (B, As, Cs, Sb, Pb, Li) systematics. Boron abundances measured thus far in fresh boninitic glasses recovered from Holes U1439C and U1442A range from 3-12 ppm, with B/Be and B/La ranging from 7.5-106 and 2-18.5, respectively. While the highest values are comparable to those observed in the most B-enriched Izu-bonin arc rocks, most of the data are at the low end of this range. Cs/Th and Pb/Ce ratios encompass the range of values encountered in IBM boninites in the literature, and are comparable to values for Izu arc lavas, while As/Sm ratios appear to be lower than in arc suites. Li concentrations are elevated relative to basaltic lavas, at 7-17 ppm, and Li/Yb ratios range from 8-22, a factor of four higher than the range encountered in volcanic arc suites. While fluid-mobile element systematics of Izu-Bonin volcanic arc lavas show evidence for inputs of two unique slab components with markedly different fluid-mobile element enrichments, the Izu-Bonin boninites can best be explained as simple mixtures of very depleted mantle and a single slab phase with high abundances of fluid-mobile species, along with elevated K, Ba, and other common subduction indicator species. Volcanic arc lavas globally show evidence for a fluid-mobile element enriched component that appears to be similar to serpentinite

  20. Bridging the Gap of Practice and Research: A Preliminary Investigation of Evidence-based Practice for Library and Information Science Research

    Directory of Open Access Journals (Sweden)

    吳寂絹 Chi-Chuan Wu

    2015-10-01

    Full Text Available The gap between practice and research is commonly found in disciplines with both ofprofessional practitioners and academic researchers. How to bridge the gap is also acontinuing concern in the field of Library and Information Studies. This article describes therecent development of Evidence-based Practice for Library and Information ScienceResearch (EBLIP, and provides analysis of the journal EBLIP including its authors’backgrounds, methods, and topics. The results show that the United States and Canadaare the two major nations of contributors; more than 70% of first authors are librarians; 76%of the articles were contributed by one single institute, co-authorship by cross-nationinstitutes were rarely seen, and demonstrates local research interests; type of co-authoredagency is primarily among libraries; 60% methods employed include questionnaires,interviews and content analysis; the coverage of topics is rather broad, and the top threecategories of research topics include Information Literacy & Instruction, Information Needs& Seeking Behavior, and Reference Services / Digital Reference Services (15%, 10%, and8%; many datasets were obtained from real library practice, and 72% of articles provide specific implications for applications which highlight the value of implementation. Manylibrarians have the research capability, and this article serves as a purpose to introduce theevidence-based research and encourage more such research done in Taiwan. Hopefully itmay benefit and further enhance the quality of library decision-making and their professionalimage.

  1. Preliminary Evidence of “Other-Race Effect”-Like Behavior Induced by Cathodal-tDCS over the Right Occipital Cortex, in the Absence of Overall Effects on Face/Object Processing

    Directory of Open Access Journals (Sweden)

    Andrea I. Costantino

    2017-11-01

    Full Text Available Neuromodulation techniques such as tDCS have provided important insight into the neurophysiological mechanisms that mediate cognition. Albeit anodal tDCS (a-tDCS often enhances cognitive skills, the role of cathodal tDCS (c-tDCS in visual cognition is largely unexplored and inconclusive. Here, in a single-blind, sham-controlled study, we investigated the offline effects of 1.5 mA c-tDCS over the right occipital cortex of 86 participants on four tasks assessing perception and memory of both faces and objects. Results demonstrated that c-tDCS does not overall affect performance on the four tasks. However, post-hoc exploratory analysis on participants' race (Caucasian vs. non-Caucasians, showed a “face-specific” performance decrease (≈10% in non-Caucasian participants only. This preliminary evidence suggests that c-tDCS can induce “other-race effect (ORE-like” behavior in non-Caucasian participants that did not show any ORE before stimulation (and in case of sham stimulation. Our results add relevant information about the breadth of cognitive processes and visual stimuli that can be modulated by c-tDCS, about the design of effective neuromodulation protocols, and have important implications for the potential neurophysiological bases of ORE.

  2. CONSTRUCCIÓN DE UNA ESCALA DE AUTOEFICACIA PARA LA INVESTIGACIÓN: PRIMERAS EVIDENCIAS DE VALIDEZ / DEVELOPMENT OF A RESEARCH SELF-EFFICACY SCALE: PRELIMINARY EVIDENCE OF VALIDITY

    Directory of Open Access Journals (Sweden)

    Sergio Alexis Dominguez-Lara

    2017-06-01

    Full Text Available RESUMEN: El objetivo del presente estudio fue examinar las primeras evidencias de validez de la Escala de Autoeficacia para Investigar (EAI, por medio del análisis del contenido de los ítems. Fue evaluada una muestra de 10 psicólogos investigadores (70% varones; Medad = 47.2 años, y de 34 estudiantes universitarios peruanos (> 70% mujeres de pregrado (n = 19 y posgrado (n = 15. Los investigadores evaluaron la relevancia y claridad de los ítems, y los estudiantes valoraron la claridad de los enunciados de la EAI. Las respuestas brindadas por los jueces fueron sistematizadas mediante la V de Aiken con intervalos de confianza, obteniendo resultados favorables. En conclusiones, la EAI presenta evidencias favorables sobre la representatividad de los ítems. Se discuten las implicancias prácticas de los hallazgos. ABSTRACT: The aim of this study was to examine the preliminary evidence of validity of the Research Self-Efficacy Scale (RSE through the analysis of item contents. A sample of ten research psychologists (70% male; Mage = 47.2 years old, and 34 Peruvian college students (> 70% female, both undergraduate (n = 19 and graduate (n = 15 was assessed. The researchers evaluated the relevance and clarity of the items, and the students, the clarity of the RSE statements. The answers given by the judges were systematized through Aiken’s V with confidence intervals, obtaining favorable results. In conclusion, the RSE exhibits favorable evidence regarding the representativity of the items. The practical implications of the findings are discussed here.

  3. Preliminary Monthly Climatological Summaries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Preliminary Local Climatological Data, recorded since 1970 on Weather Burean Form 1030 and then National Weather Service Form F-6. The preliminary climate data pages...

  4. Chicken Astrovirus Infection: Minireview and Preliminary Serologic ...

    African Journals Online (AJOL)

    Chicken Astrovirus Infection: Minireview and Preliminary Serologic Evidence of Antigenically and Genetically Distinct Chicken Astroviruses in Nigerian ... This knowledge will engender research into the prevalence, distribution, pathogenicity and economic losses caused by these diseases, and ultimately lead to the design ...

  5. Recombinant pollen allergens from Dactylis glomerata: preliminary evidence that human IgE cross-reactivity between Dac g II and Lol p I/II is increased following grass pollen immunotherapy.

    Science.gov (United States)

    Roberts, A M; Van Ree, R; Cardy, S M; Bevan, L J; Walker, M R

    1992-07-01

    We previously described the isolation of three identical complementary DNA (cDNA) clones, constructed from Orchard/Cocksfoot grass (Dactylis glomerata) anther messenger RNA (mRNA), expressing a 140,000 MW beta-galactosidase fusion protein recognized by IgE antibodies in atopic sera. Partial nucleotide sequencing and inferred amino acid sequence showed greater than 90% homology with the group II allergen from Lolium perenne (Lol II) indicating they encode the group II equivalent, Dac g II. Western blot immunoprobing of recombinant lysates with rabbit polyclonal, mouse monoclonal and human polyclonal antisera demonstrates immunological identity between recombinant Dac g II, Lol p I and Lol p II. Similar cross-identity is observed with pollen extracts from three other grass species: Festuca rubra, Phleum pratense and Anthoxanthum odoratum. Recombinant Dac g II was recognized by species- and group-cross-reactive human IgE antibodies in 33% (4/12) of sera randomly selected from grass-sensitive individuals and in 67% (14/21) of sera from patients receiving grass pollen immunotherapy, whilst 0/4 sera from patients receiving venom immunotherapy alone contained Dac g II cross-reactive IgE. Cross-reactive IgG4 antibodies were detectable in 95% of sera from grass pollen immunotherapy patients. These preliminary data suggest that conventional grass pollen allergoid desensitization immunotherapy may induce IgE responses to a cross-reactive epitope(s) co-expressed by grass pollen groups I and II (and possibly group III) allergens.

  6. Measuring social skills of children and adolescents in a Chinese population: Preliminary evidence on the reliability and validity of the translated Chinese version of the Social Skills Improvement System-Rating Scales (SSIS-RS-C).

    Science.gov (United States)

    Cheung, Phoebe P P; Siu, Andrew M H; Brown, Ted

    2017-01-01

    The Social Skills Improvement System-Rating Scales (SSIS-RS; Gresham & Elliott, 2008) are designed to assist in the screening and classification of students (aged 5-18 years) who are suspected of presenting with social skills deficits and to offer guidelines in the development of interventions to remediate those types of problems. The objective of this study is to examine the preliminary reliability and validity of the translated Chinese version of the SSIS-RS, referred to as the SSIS-RS-C. In this study, parent-reported social skills and problem behaviors among students with typical development (n=79) were compared with those of age- and gender-matched students with a known developmental disability (n=79) using the SSIS-RS-C. The results indicated that the SSIS-RS-C subscale scores in all the disability groups were significantly different except for those in the Assertion scale for one disability group. Furthermore, the normative sample of typically developing children and adolescents (aged 5-12 and 13-18 years, n=567) from Hong Kong was established to improve the psychometric properties of the SSIS-RS-C. There were moderate to strong relationships between the common subscales across all forms of the SSIS-RS-C. Acceptable to excellent levels of internal consistency across all common subscales was also obtained. The scores for the Hong Kong sample (n=567) derived from the use of the SSIS-RS-C were then compared to the normative sample scores from the American version of the SSIS-RS. It was found that there were statistically significant differences on five out of the seven SSIS-RS-C Social Skill subscales for children aged 5-12 years and on four out of the seven SSIS-RS-C Social Skills subscales for the adolescent group (aged 13-18 years). Also, there were statistically significant differences between the American and Hong Kong samples on all of the SSIS-RS-C Problem Behavior scale scores. It was concluded that the SSIS-RS-C is a promising instrument for clinicians

  7. Evidence of past climate change in the Little Ice Age and of the Pacific Decadal Oscillation periodicity in Africa: comparison between two neighbor stalagmites from Namibia and Botswana (preliminary results)

    Science.gov (United States)

    Voarintsoa, N. G.; Railsback, L. B.; Liang, F.; Brook, G. A.; Cheng, H.; Edwards, R.

    2013-12-01

    Stalagmites are potential sources of paleoenvironmental records because their characteristics respond to climate change. In this preliminary study we compare isotopic values resolvable at annual to bi-annual scale from two stalagmites from caves in Proterozoic dolomitic marbles, as a proxy for the past climate variability in Southern Africa. Stalagmite DP1 is from Dante Cave in the Otjozondjupa region of Namibia, and Stalagmite BC97-14 is from Bone Cave, in the Koanaka Hills of Northwest Botswana, ~125km west of the Okavango Delta. Dante and Bone Cave receive respectively ~532 and ~475mm annual rainfall with an annual average temperature of 21.0°C and 22.6°C. Both caves are in semi-arid areas with highly seasonal rainfall. Vegetation is distinctive for each location: deciduous woodland savanna with a relatively high diversity of scattered tall trees on the hill in which Dante is located and a sparser tree cover on the hillsite of Bone Cave area. The data from the two stalagmites are very different, reflecting the distinctive hydrological and vegetation settings of the caves where they formed. δ18O in BC97-14 is highly variable, ranging from -11.6 to -5.8 ‰, while δ13C is nearly constant (-10.5 to -8.5 ‰). In contrast, δ13C and δ18O are covariant in DP1, with much higher δ13C values (-10.8 to -5.1‰) and much lower δ18O (-11.7 to -6.5 ‰) compared to that of Bone Cave. The distance from the water vapor source (Indian Ocean) might explain the generally lower δ18O values from the Namibian stalagmite compared to that of Botswana; while the difference in vegetation cover reflects the difference between δ13C for the two areas. Regardless of this isotopic difference, the stalagmite data for Bone Cave show a marked 15- to 22-year periodicity that is much more subdued in the Namibia speleothem. This cycle matches with the 17- or 18-year periodicity in the Botswana historical rainfall record. The periodicity is very well pronounced between AD 1825 to 1925

  8. First derivative spectrofluorimetric determination of zopiclone and its degradation product, 2-amino-5-chloropyridine, in pharmaceutical formulations with preliminary tool in biological fluids for clinical evidence of zopiclone intake

    Science.gov (United States)

    Al-Attas, Amirah S.; Nasr, Jenny Jeehan; Shalan, Shereen; Belal, Fathalla

    2017-06-01

    A simple, fast, sensitive and stability-indicating derivative spectrofluorimetric method is presented for the assay of zopiclone (ZOP), a drug with hypnotic effect, and its main degradation product and major contaminant, 2-amino-5-chloropyridine (ACP). The method is based on measuring the inherent fluorescence intensity of both drugs at λex = 300 nm in methanol, then differentiation using D1 (first derivative technique). The developed method was found to be rectilinear over a range of 0.2-4 μg/mL of ZOP and 4-100 ng/mL of ACP. The limits of detection were 0.05 μg/mL of ZOP and 0.2 ng/mL of ACP with the limit of quantitation of 0.17 μg/mL of ZOP and 0.7 ng/mL of ACP. The outcoming results of the proposed method were compared to those obtained by a reference method showing no significant statistical difference between them concerning precision and accuracy. Additionally, the developed method was applied for detecting ACP in spiked human urine and plasma specimens as a tool of clinical evidence of zopiclone intake that can be easily implemented in forensic laboratories. The proposed method was validated as per ICH guidelines.

  9. UVISS preliminary visibility analysis

    DEFF Research Database (Denmark)

    Betto, Maurizio

    1998-01-01

    The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part of the w......The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part...... of the work is also to setup the kernel of a software tool for the visibility analysis thatshould be easily expandable to consider more complex strucures for future activities.This analysis is part of the UVISS assessment study and it is meant to provide elementsfor the definition and the selection...

  10. Preliminary y remarks y

    Indian Academy of Sciences (India)

    ranjeetha

    Preliminary. Rohini M. G. Chair, WiS Pan. March 1. S.N. S.Adar y remarks y. Godbole nel of IASc. 11 2014, , rsh College. Page 2. What will this. Little bit about the pro. Science: Career in Scie today and a bit about th. (WiS) Panel of the Indi. Sciences' and by implic. Sciences and by implic .... education but more to attr.

  11. The effects of midday nap duration on the risk of hypertension in a middle-aged and older Chinese population: a preliminary evidence from the Tongji-Dongfeng Cohort Study, China.

    Science.gov (United States)

    Cao, Zhongqiang; Shen, Lijun; Wu, Jing; Yang, Handong; Fang, Weimin; Chen, Weihong; Yuan, Jing; Wang, Youjie; Liang, Yuan; Wu, Tangchun

    2014-10-01

    Evidence from epidemiological studies suggested that shorter and longer duration of nocturnal sleeping may increase the risk of hypertension for older adults. Little is known about the duration of midday nap on the variability of blood pressure among older adults. In this study, we examined whether duration of habitual midday nap is associated with level of blood pressure or the risk of hypertension in a middle-aged and older Chinese population. A total of 27 009 participants (mean age 63.6 years) from Dongfeng-Tongji Cohort Study received baseline examination including physical examination and laboratory tests, and a face-to-face-interview including demographic information, disease history, and lifestyle. Participants were categorized into five groups according to nap duration, such as no napping, less than 30 min, 30∼60 min, 60∼90 min, and at least 90 min. A series of categorical logistic regression models was used to examine the odd ratios of nap duration with hypertension. The level of SBP and DBP increased significantly with longer duration of habitual midday napping. Nappers with longer nap duration had considerably higher rate of hypertension. The longer duration of napping was related to higher blood pressure level and was associated with a higher risk of hypertension. After adjusting for possible confounders, the longer duration (>60 min) of napping was still associated with hypertension : Our findings showed that the practice of longer afternoon nap is associated with a higher increased risk of hypertension, independent of several covariates. Further prospective researches are needed to examine the midday nap duration for development of hypertension.

  12. Environmental Survey preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    1988-04-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Sandia National Laboratories conducted August 17 through September 4, 1987. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with Sandia National Laboratories-Albuquerque (SNLA). The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at SNLA, and interviews with site personnel. 85 refs., 49 figs., 48 tabs.

  13. Effectiveness of Service Dogs for Veterans with PTSD: Preliminary Outcomes.

    Science.gov (United States)

    Vincent, Claude; Belleville, Geneviève; Gagnon, Dany H; Dumont, Frédéric; Auger, Edouard; Lavoie, Vicky; Besemann, Markus; Champagne, Noël; Lessart, Geneviève

    2017-01-01

    Limited scientific evidence on the effectiveness of psychiatric service dogs used by Veterans with post-traumatic stress disorder (PTSD) is available. This study investigated their short-term effectiveness among 15 Canadian veterans who received a first psychiatric service dog. Preliminary results suggest potential beneficial effects at 3 months on the psychiatric symptoms.

  14. OMEGA Upgrade preliminary design

    International Nuclear Information System (INIS)

    Craxton, R.S.

    1989-10-01

    The OMEGA laser system at the Laboratory for Laser Energetics of the University of Rochester is the only major facility in the United States capable of conducting fully diagnosed, direct-drive, spherical implosion experiments. As such, it serves as the national Laser Users Facility, benefiting scientists throughout the country. The University's participation in the National Inertial Confinement Fusion (ICF) program underwent review by a group of experts under the auspices of the National Academy of Sciences (the Happer Committee) in 1985. The Happer Committee recommended that the OMEGA laser be upgraded in energy to 30 kJ. To this end, Congress appropriated $4,000,000 for the preliminary design of the OMEGA Upgrade, spread across FY88 and FY89. This document describes the preliminary design of the OMEGA Upgrade. The proposed enhancements to the existing OMEGA facility will result in a 30-kHJ, 351-nm, 60-beam direct-drive system, with a versatile pulse-shaping facility and a 1%--2% uniformity of target drive. The Upgrade will allow scientists to explore the ignition-scaling regime, and to study target behavior that is hydrodynamically equivalent to that of targets appropriate for a laboratory microfusion facility (LMF). In addition, it will be possible to perform critical interaction experiments with large-scale-length uniformly irradiated plasmas

  15. Reading and writing assessment scales: preliminary reliability evidences.

    Science.gov (United States)

    Kida, Adriana de Souza Batista; Chiari, Brasília Maria; Avila, Clara Regina Brandão de

    2010-01-01

    Reliability of Reading and Writing Assessment Instruments. To investigate the reliability of two scales created to evaluate both reading and writing of children with ages between 8:0 and 11:11 years. Two scales were created: a reading scale, composed of 12 testing items organized into four competency fields (letter knowledge and phonographemic relation, decoding of isolated items, reading fluency, reading comprehension), and a writing scale, with five items organized into three fields (letter writing and graphophonemic relation, codification of isolated items, writing construction). One hundred students (64 girls) from Public Schools, with ages raging between 8:0 and 11:11 years, were selected. Twenty students (12 girls) participated in the applicability study, resulting in the study version of the Scales. These scales were later applied to the remaining 80 students (52 girls). The obtained responses were assessed and computed for score assignment: item scores, competence field score (CFS) and raw scale score (RSS). Data were submitted to statistical analysis: the Cronbach's alpha coefficient was calculated and correlations between items (Pearson's correlation coefficient) were verified. A significance level of 0.05 was used. a = 0.866 and a = 0.461 were obtained for the Reading and Writing Scales, respectively. Correlations between the items were observed, ranging from weak to strong, and confirmed the alpha values. The Reading Scale was proven reliable, achieving acceptable levels for diagnostic instruments; the Writing Scale did not present an acceptable reliability level to measure the performance of the tested children.

  16. Preliminary evidence suggests extra-pair mating in the endangered ...

    African Journals Online (AJOL)

    This study utilized four microsatellite genetic markers, originally developed for the African grey parrot. Parentage testing was undertaken using genotype comparisons with the dominant pair within the breeding group as well as auxiliary males where available. Although four markers were insufficient to provide conclusive ...

  17. Preliminary rail access study

    International Nuclear Information System (INIS)

    1990-01-01

    The Yucca Mountain site, located on the southwestern edge of the Nevada Test Site, is an undeveloped area under investigation as a potential site for nuclear waste disposal by the US Department of Energy. The site currently lacks rail service and an existing rail right-of-way. If the site is suitable and selected for development as a disposal site, rail service is desirable to the Office of Civilian Radioactive Waste Management Program because of the potential of rail to reduce number of shipments and costs relative to highway transportation. This preliminary report is a summary of progress to date for activities to identify and evaluate potential rail options from major rail carriers in the region to the Yucca Mountain site. It is currently anticipated that the rail spur will be operational after the year 2000. 9 refs., 13 figs., 2 tabs

  18. The Preliminaries of a Reference

    DEFF Research Database (Denmark)

    Butler, Graham; Sadl, Urska

    2018-01-01

    On 11 June 2015, the President of the First Chamber of the Court of Justice of the EU (the Court) issued an order to delete Bogdan Chain v Atlanco Ltd (C-189/14) from the Registry. This comment and the reflection are thus not motivated by a judgment, but rather by the reasons why the Court after ...... in the preliminary reference procedure. It highlights the fact that preliminary references can only work when the preliminaries of a reference—the culture of sincere co-operation and litigation, efficient communication, and flexible procedural rules—are in place....

  19. Preliminary Analysis of Photoreading

    Science.gov (United States)

    McNamara, Danielle S.

    2000-01-01

    The purpose of this project was to provide a preliminary analysis of a reading strategy called PhotoReading. PhotoReading is a technique developed by Paul Scheele that claims to increase reading rate to 25,000 words per minute (Scheele, 1993). PhotoReading itself involves entering a "relaxed state" and looking at, but not reading, each page of a text for a brief moment (about I to 2 seconds). While this technique has received attention in the popular press, there had been no objective examinations of the technique's validity. To examine the effectiveness of PhotoReading, the principal investigator (i.e., trainee) participated in a PhotoReading workshop to learn the technique. Parallel versions of two standardized and three experimenter-created reading comprehension tests were administered to the trainee and an expert user of the PhotoReading technique to compare the use of normal reading strategies and the PhotoReading technique by both readers. The results for all measures yielded no benefits of using the PhotoReading technique. The extremely rapid reading rates claimed by PhotoReaders were not observed; indeed, the reading rates were generally comparable to those for normal reading. Moreover, the PhotoReading expert generally showed an increase in reading time when using the PhotoReading technique in comparison to when using normal reading strategies to process text. This increase in reading time when PhotoReading was accompanied by a decrease in text comprehension.

  20. 76 FR 65061 - Manual for Courts-Martial; Proposed Evidence Amendments

    Science.gov (United States)

    2011-10-19

    ... preserved. Rule 104. Preliminary Questions (a) In General. The military judge must decide any preliminary... granted, or evidence is admissible. In so deciding, the military judge is not bound by evidence rules... of the Judge Advocate General, Criminal Law Division, 2200 Pentagon, Room 3B548, Washington DC, 32101...

  1. Immaterial Evidence

    Directory of Open Access Journals (Sweden)

    Ivanov N. A.

    2012-11-01

    Full Text Available It is substantiated in the article that some of the objects which either could serve as instruments of a crime for criminal actions, or they were obtained through the commission of a crime, are immaterial objects, and they may be conditionally designated as evidence. The author relates to immaterial evidence physical fields, radiation, undocumented information, computer programs, property rights, intangible benefits, heat and electric power, and information processes.

  2. Digital evidence

    Directory of Open Access Journals (Sweden)

    Lukić Tatjana

    2012-01-01

    Full Text Available Although computer makes human activities faster and easier, innovating and creating new forms of work and other kinds of activities, it also influenced the criminal activity. The development of information technology directly affects the development of computer forensics without which, it can not even imagine the discovering and proving the computer offences and apprehending the perpetrator. Information technology and computer forensic allows us to detect and prove the crimes committed by computer and capture the perpetrators. Computer forensics is a type of forensics which can be defined as a process of collecting, preserving, analyzing and presenting digital evidence in court proceedings. Bearing in mind, that combat against crime, in which computers appear as an asset or object of the offense, requires knowledge of digital evidence as well as specific rules and procedures, the author in this article specifically addresses the issues of digital evidence, forensic (computer investigation, specific rules and procedures for detecting, fixing and collecting digital evidence and use of this type of evidence in criminal proceedings. The author also delas with international standards regarding digital evidence and cyber-space investigation.

  3. Technetium removal: preliminary flowsheet options

    International Nuclear Information System (INIS)

    Eager, K.M.

    1995-01-01

    This document presents the results of a preliminary investigation into options for preliminary flowsheets for 99Tc removal from Hanford Site tank waste. A model is created to show the path of 99Tc through pretreatment to disposal. The Tank Waste Remediation (TWRS) flowsheet (Orme 1995) is used as a baseline. Ranges of important inputs to the model are developed, such as 99Tc inventory in the tanks and important splits through the TWRS flowsheet. Several technetium removal options are discussed along with sensitivities of the removal schemes to important model parameters

  4. Preliminary investigations of Agrobacterium -mediated ...

    African Journals Online (AJOL)

    Preliminary steps in the genetic transformation of indica rice MR219 was investigated in the plant- Agrobacterium tumefaciens interaction. Agrobacterium tumefaciens strain LBA 4404 carrying a binary vector pCAMBIA 1305.2 harboring the modified GUS gene driven by the CaMV 35S promoter was used. Various ...

  5. 45 CFR 150.217 - Preliminary determination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Preliminary determination. 150.217 Section 150.217... Are Failing To Substantially Enforce HIPAA Requirements § 150.217 Preliminary determination. If, at... designees). (b) Notifies the State of CMS's preliminary determination that the State has failed to...

  6. 19 CFR 4.8 - Preliminary entry.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Preliminary entry. 4.8 Section 4.8 Customs Duties... VESSELS IN FOREIGN AND DOMESTIC TRADES Arrival and Entry of Vessels § 4.8 Preliminary entry. (a) Generally. Preliminary entry allows a U.S. or foreign vessel arriving under circumstances that require it to formally...

  7. 29 CFR 1955.31 - Preliminary conference.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Preliminary conference. 1955.31 Section 1955.31 Labor... (CONTINUED) PROCEDURES FOR WITHDRAWAL OF APPROVAL OF STATE PLANS Preliminary Conference and Discovery § 1955.31 Preliminary conference. (a) Upon his own motion, or the motion of a party, the administrative law...

  8. Exploratory shaft facility preliminary designs - Permian Basin

    International Nuclear Information System (INIS)

    1983-09-01

    The purpose of the Preliminary Design Report, Permian Basin, is to provide a description of the preliminary design for an Exploratory Shaft Facility in the Permian Basin, Texas. This issue of the report describes the preliminary design for constructing the exploratory shaft using the Large Hole Drilling method of construction and outlines the preliminary design and estimates of probable construction cost. The Preliminary Design Report is prepared to complement and summarize other documents that comprise the design at the preliminary stage of completion, December 1982. Other design documents include drawings, cost estimates and schedules. The preliminary design drawing package, which includes the construction schedule drawing, depicts the descriptions in this report. For reference, a list of the drawing titles and corresponding numbers are included in the Appendix. The report is divided into three principal sections: Design Basis, Facility Description, and Construction Cost Estimate. 30 references, 13 tables

  9. Preliminary results from APE-100

    International Nuclear Information System (INIS)

    Bartoloni, A.; Battista, C.; Cabasino, S.; Marzano, F.; Paolucci, P.S.; Pech, J.; Rapuano, F.; Sarno, R.; Todesco, G.M.; Torelli, M.; Tross, W.; Vicini, P.; Tripiccione, R.; Cabibbo, N.; Salina, G.; Fucci, A.; Lubicz, V.; Maiani, L.; Martinelli, G.; Vladikas, A.

    1993-01-01

    We present the preliminary results obtained on the 6 Gigaflop prototype which is the building block of the APE-100 computer. Results are presented for pseudoscalar and vector mesons for the Wilson and the improved action with a statistics of about 100 configurations. Static heavy-light meson propagator have also been studied for different smeared operators. We find that large smearing (≥ 9) are bad projectors on the lightest pseudoscalar states. (orig.)

  10. Preliminary Results of the Louisiana Sex Offender Treatment Program

    Directory of Open Access Journals (Sweden)

    Lee A. Underwood

    2015-12-01

    Full Text Available The purpose of this study was to offer preliminary support for the Louisiana Sex Offender Treatment Program (LSOTP in addressing the needs of juvenile sex offenders. Research objectives were (1 to offer statistical evidence for reductions in anxiety, depression, cognitive distortion and negative attitudes towards women comparing a group of 21 adolescents, 12 of whom received services as usual and nine of whom participated in the LSOTP. A controlled experimental evaluation design was utilized. The juvenile sex offenders were randomly assigned to the experimental group for 12 weeks receiving treatment services and a control group receiving care “as usual” in a residential group care program. Participants in the experimental group experienced statistically significant decreases in cognitive distortions related specifically to rape and molestation.The results of this study offer preliminary support of the LSOTP as a best practices alternative to other treatment modalities.

  11. The professional clothing bank as evidence-based practice.

    Science.gov (United States)

    Bishop, SueZanne Monique

    2015-01-01

    Little research exists linking interview-appropriate attire to improved employment outcomes for women. Thus, it appears that the professional clothing bank has not been investigated as evidence-based practice. To provide preliminary evidence for clothing banks, in this article the author synthesizes findings from existing research on the provision of a professional clothing bank as a means for offering interview-appropriate attire to poor women in job readiness programming. For context, job readiness programs are explored and a case study of one program operating a professional clothing bank is presented. Finally, preliminary considerations for planning and implementing clothing banks based on this literature review are given.

  12. Preliminary

    Directory of Open Access Journals (Sweden)

    Desde el Jardín de Freud

    2017-01-01

    Full Text Available Desde el Jardín de Freud is indexed in the IBN-Publindex (Colciencias in category C, and the following databases and catalogs: EBSCO, ProQuest, Google Scholar, CLASE, Latindex, Dialnet, Rebiun, Doaj, e-revistas and Library Luis Angel Arango virtual.

  13. Evidence-Based Psychological Assessment.

    Science.gov (United States)

    Bornstein, Robert F

    2017-01-01

    In recent years there has been increasing emphasis on evidence-based practice in psychology (EBPP), and as is true in most health care professions, the primary focus of EBPP has been on treatment. Comparatively little attention has been devoted to applying the principles of EBPP to psychological assessment, despite the fact that assessment plays a central role in myriad domains of empirical and applied psychology (e.g., research, forensics, behavioral health, risk management, diagnosis and classification in mental health settings, documentation of neuropsychological impairment and recovery, personnel selection and placement in organizational contexts). This article outlines the central elements of evidence-based psychological assessment (EBPA), using the American Psychological Association's tripartite definition of EBPP as integration of the best available research with clinical expertise in the context of patient characteristics, culture, and preferences. After discussing strategies for conceptualizing and operationalizing evidence-based testing and evidence-based assessment, 6 core skills and 3 meta-skills that underlie proficiency in psychological assessment are described. The integration of patient characteristics, culture, and preferences is discussed in terms of the complex interaction of patient and assessor identities and values throughout the assessment process. A preliminary framework for implementing EBPA is offered, and avenues for continued refinement and growth are described.

  14. TCA High Lift Preliminary Assessment

    Science.gov (United States)

    Wyatt, G. H.; Polito, R. C.; Yeh, D. T.; Elzey, M. E.; Tran, J. T.; Meredith, Paul T.

    1999-01-01

    This paper presents a TCA (Technology Concept Airplane) High lift Preliminary Assessment. The topics discussed are: 1) Model Description; 2) Data Repeatability; 3) Effect of Inboard L.E. (Leading Edge) Flap Span; 4) Comparison of 14'x22' TCA-1 With NTF (National Transonic Facility) Modified Ref. H; 5) Comparison of 14'x22' and NTF Ref. H Results; 6) Effect of Outboard Sealed Slat on TCA; 7) TCA Full Scale Build-ups; 8) Full Scale L/D Comparisons; 9) TCA Full Scale; and 10) Touchdown Lift Curves. This paper is in viewgraph form.

  15. Preliminary ECLSS waste water model

    Science.gov (United States)

    Carter, Donald L.; Holder, Donald W., Jr.; Alexander, Kevin; Shaw, R. G.; Hayase, John K.

    1991-01-01

    A preliminary waste water model for input to the Space Station Freedom (SSF) Environmental Control and Life Support System (ECLSS) Water Processor (WP) has been generated for design purposes. Data have been compiled from various ECLSS tests and flight sample analyses. A discussion of the characterization of the waste streams comprising the model is presented, along with a discussion of the waste water model and the rationale for the inclusion of contaminants in their respective concentrations. The major objective is to establish a methodology for the development of a waste water model and to present the current state of that model.

  16. Preliminary considerations concerning actinide solubilities

    International Nuclear Information System (INIS)

    Newton, T.W.; Bayhurst, B.P.; Daniels, W.R.; Erdal, B.R.; Ogard, A.E.

    1980-01-01

    Work at the Los Alamos Scientific Laboratory on the fundamental solution chemistry of the actinides has thus far been confined to preliminary considerations of the problems involved in developing an understanding of the precipitation and dissolution behavior of actinide compounds under environmental conditions. Attempts have been made to calculate solubility as a function of Eh and pH using the appropriate thermodynamic data; results have been presented in terms of contour maps showing lines of constant solubility as a function of Eh and pH. Possible methods of control of the redox potential of rock-groundwater systems by the use of Eh buffers (redox couples) is presented

  17. Metacognitions in desire thinking: a preliminary investigation.

    Science.gov (United States)

    Caselli, Gabriele; Spada, Marcantonio M

    2010-10-01

    Desire thinking is defined as a voluntary thinking process orienting to prefigure images, information and memories about positive target-related experience. Recent research has highlighted the role of desire thinking in the maintenance of addictive, eating and impulse control disorders. Currently little is known about metacognitions in desire thinking. To investigate: (1) the presence and content of desire thinking during a desire experience; (2) the presence of metacognitive beliefs in desire thinking; (3) the goal of desire thinking; (4) attentional focus during desire thinking; and (5) the impact of desire thinking on craving. Twenty-four individuals with a diagnosis of either alcohol abuse, bulimia nervosa, pathological gambling or smoking dependence were assessed using a semi-structured interview. Findings indicated that participants engaged in desire thinking and endorsed both positive and negative metacognitive beliefs about this process. The goal of desire thinking was to regulate internal states. Participants also reported that during a desire experience their attentional focus was continuously shifting between internal state and external context and that engaging in desire thinking increased craving. These findings provide preliminary evidence that metacognitions play a role in desire thinking.

  18. Prescribing smoked cannabis for chronic noncancer pain: preliminary recommendations.

    Science.gov (United States)

    Kahan, Meldon; Srivastava, Anita; Spithoff, Sheryl; Bromley, Lisa

    2014-12-01

    To offer preliminary guidance on prescribing smoked cannabis for chronic pain before the release of formal guidelines. We reviewed the literature on the analgesic effectiveness of smoked cannabis and the harms of medical and recreational cannabis use. We developed recommendations on indications, contraindications, precautions, and dosing of smoked cannabis, and categorized the recommendations based on levels of evidence. Evidence is mostly level II (well conducted observational studies) and III (expert opinion). Smoked cannabis might be indicated for patients with severe neuropathic pain conditions who have not responded to adequate trials of pharmaceutical cannabinoids and standard analgesics (level II evidence). Smoked cannabis is contraindicated in patients who are 25 years of age or younger (level II evidence); who have a current, past, or strong family history of psychosis (level II evidence); who have a current or past cannabis use disorder (level III evidence); who have a current substance use disorder (level III evidence); who have cardiovascular or respiratory disease (level III evidence); or who are pregnant or planning to become pregnant (level II evidence). It should be used with caution in patients who smoke tobacco (level II evidence), who are at increased risk of cardiovascular disease (level III evidence), who have anxiety or mood disorders (level II evidence), or who are taking higher doses of opioids or benzodiazepines (level III evidence). Cannabis users should be advised not to drive for at least 3 to 4 hours after smoking, for at least 6 hours after oral ingestion, and for at least 8 hours if they experience a subjective "high" (level II evidence). The maximum recommended dose is 1 inhalation 4 times per day (approximately 400 mg per day) of dried cannabis containing 9% delta-9-tetrahydrocannabinol (level III evidence). Physicians should avoid referring patients to "cannabinoid" clinics (level III evidence). Future guidelines should be based on

  19. Development and Preliminary Validation of the Time Management for Exercise Scale

    Science.gov (United States)

    Hellsten, Laurie-ann M.; Rogers, W. Todd

    2009-01-01

    The purpose of this study was to collect preliminary validity evidence for a time management scale for exercise. An initial pool of 91 items was developed from existing literature. Ten exercise/health psychologists evaluated each of the items in terms of relevance and representativeness. Forty-nine items met all criteria. Exploratory factor…

  20. 75 FR 21314 - Medicaid Program; Final FY 2008, Revised Preliminary FY 2009, and Preliminary FY 2010...

    Science.gov (United States)

    2010-04-23

    ... ``preliminary.'' Only after we receive States' reports of the actual medical assistance expenditures through the... and safety effects, distributive impacts, and equity). A regulatory impact analysis (RIA) must be... 0938-AP66 Medicaid Program; Final FY 2008, Revised Preliminary FY 2009, and Preliminary FY 2010...

  1. Preliminary Studies On The Limnological Stock Assessment ...

    African Journals Online (AJOL)

    Preliminary Studies On The Limnological Stock Assessment, Productivity And Potential Fish Yield Of Ojirami Reservoir, Edo State, Nigeria. ... Tropical Freshwater Biology ... This report has only provided preliminary data on the reservoir but it is hoped that future studies would benefit from this initial benchmark information.

  2. Preliminary Phytochemical Screening, Acute Oral Toxicity and ...

    African Journals Online (AJOL)

    Preliminary Phytochemical Screening, Acute Oral Toxicity and Anticonvulsant Activity of the Berries of Solanum nigrum Linn. HL Son, PTH Yen. Abstract. Purpose: To investigate the preliminary phytochemical properties, acute oral toxicity and anticonvulsant activity of the berries of Solanum nigrum Linn (S. nigrum) Methods: ...

  3. Plutonium Immobilization Can Loading Preliminary Specifications

    Energy Technology Data Exchange (ETDEWEB)

    Kriikku, E.

    1998-11-25

    This report discusses the Plutonium Immobilization can loading preliminary equipment specifications and includes a process block diagram, process description, equipment list, preliminary equipment specifications, plan and elevation sketches, and some commercial catalogs. This report identifies loading pucks into cans and backfilling cans with helium as the top priority can loading development areas.

  4. 23 CFR 645.109 - Preliminary engineering.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Preliminary engineering. 645.109 Section 645.109 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS UTILITIES Utility Relocations, Adjustments, and Reimbursement § 645.109 Preliminary engineering. (a) As...

  5. Preliminary Context Analysis of Community Informatics Social ...

    African Journals Online (AJOL)

    Preliminary context analysis is always part of the feasibility study phase in the development of information system for Community Development (CD) purposes. In this paper, a context model and a preliminary context analysis are presented for Social Network Web Application (SNWA) for CD in the Niger Delta region of ...

  6. KALIMER preliminary conceptual design report

    International Nuclear Information System (INIS)

    Hahn, Do Hee; Kim, Y. J.; Kim, Y. G. and others

    2000-08-01

    This report, which summarizes the result of preliminary conceptual design activities during Phase 1, follows the format of safety analysis report. The purpose of publishing this report is to gather all of the design information developed so far in a systematic way so that KALIMER designers have a common source of the consistent design information necessary for their future design activities. This report will be revised and updated as design changes occur and more detailed design specification is developed during Phase 2. Chapter 1 describes the KALIMER Project. Chapter 2 includes the top level design requirements of KALIMER and general plant description. Chapter 3 summarizes the design of structures, components, equipment and systems. Specific systems and safety analysis results are described in the remaining chapters. Appendix on the HCDA evaluation is attached at the end of this report

  7. KALIMER preliminary conceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, Do Hee; Kim, Y. J.; Kim, Y. G. and others

    2000-08-01

    This report, which summarizes the result of preliminary conceptual design activities during Phase 1, follows the format of safety analysis report. The purpose of publishing this report is to gather all of the design information developed so far in a systematic way so that KALIMER designers have a common source of the consistent design information necessary for their future design activities. This report will be revised and updated as design changes occur and more detailed design specification is developed during Phase 2. Chapter 1 describes the KALIMER Project. Chapter 2 includes the top level design requirements of KALIMER and general plant description. Chapter 3 summarizes the design of structures, components, equipment and systems. Specific systems and safety analysis results are described in the remaining chapters. Appendix on the HCDA evaluation is attached at the end of this report.

  8. Psychohistory and Slavery: Preliminary Issues.

    Science.gov (United States)

    Adams, Kenneth Alan

    2015-01-01

    "Psychohistory and Slavery: Preliminary Issues," begins an examination of slavery in the antebellum South. The paper suggests that how slavery and the group-fantasy of white male supremacy were perpetuated among slaveholders is a question of fundamental importance for psychohistorians. The family and childrearing are the focus of attention. Given the ferocity of slavery, it is argued that the psychological and emotional consequences of this barbarism were not limited to the slaves themselves, but had significant impact on the slaveholders as well-their parenting, their children, and their children's parenting of the next generation. In each generation the trauma of slavery was injected into slaveholder children and became a fundamental component of elite Southern personality.

  9. Preliminary hazards analysis -- vitrification process

    Energy Technology Data Exchange (ETDEWEB)

    Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.

  10. Preliminary hazards analysis -- vitrification process

    International Nuclear Information System (INIS)

    Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P.

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility's construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment

  11. Improving eating disorders mental health literacy: a preliminary evaluation of the "Should I say something?" workshop.

    Science.gov (United States)

    Gratwick-Sarll, Kassandra; Bentley, Caroline

    2014-01-01

    A repeated measures, uncontrolled, preliminary evaluation of a single 3-hour workshop-"Should I Say Something?"-aimed at improving eating disorders mental health literacy, was conducted in a sample of 177 university undergraduates. Following participation in the workshop, significant increases in eating disorder recognition and knowledge, and significant decreases in stigmatizing attitudes, were reported by participants. Moreover, 85% of participants reported that they provided assistance to someone whom they suspected had a mental health condition, including an eating disorder, during the 3-month follow-up period. This study provides preliminary evidence that "Should I Say Something?" may be effective in improving the mental health literacy of young people.

  12. Preliminary cardiological examinations in deaf children.

    Science.gov (United States)

    Rokicki, Władysław; Markiewicz-Łoskot, Grazyna; Michalewska, Aleksandra; Włudarczyk, Witold; Mizia, Magdalena

    2002-01-01

    There is some evidence that deaf children are more threatened than the general population by dangerous heart arrhythmias. An example is Jervell-Lange-Nielsen syndrome (one of the forms of long QT syndrome) which is characterised primarily by congenital deafness and prolongation of the QT interval. The aim of this study was to perform preliminary cardiological examinations on 162 deaf children (76 girls and 86 boys, 3-15 years old, mean age 10.5 +/- 2.8 years) who attend the Regional School Centre for Deaf Children in Katowice. The data in our analysis was obtained from case histories (school records and special questionnaires sent to parents), physical examinations with special regard to the cardiovascular system, double blood pressure measurement and 12 lead surface electrocardiogram. In the studied group, 90 children (55.5%) were congenitally deaf. Within this group, 24 children manifested tachycardia while 4 children manifested-bradycardia. A-V block of I degree was found in 3 children. Incomplete right bundle branch block (RBBB) was observed in 44 children while a complete RBBB was noticed in 1 child. QTc interval was prolonged (> 0.44s) in 12 children suffering from congenital form of deafness and in 16 children suffering from all causes of deafness. On the basis of case history, physical examination, and standard 12-lead electrocardiogram, we established the occurrence of risk factors according to the new diagnostic criteria of Schwartz et al. with relative points assigned to the electrocardiographical, clinical and familial findings. These points when summed up represent the risk of sudden death caused by ventricular arrhythmia due to long QT syndrome. In the studied group (according to the Schwartz criteria), 2 (1.2%) children had high probability (> or = 4 points) of long QT syndrome (LQTS), 25 (15.4%) children had intermediate probability of LQTS (2-3 points) and 135 children had low probability of LQTS (< or = 1 point).

  13. Preliminary design of smart fuel

    International Nuclear Information System (INIS)

    Kim, Y.; Ha, D.; Park, S.; Nahm, K.; Lee, K.; Kim, J.

    2007-01-01

    SMART (System-integrated Modular Advanced Reactor) is a novel light water rector with a modular, integral primary system configuration. This concept has been developing a 660 MWt by Korean Nuclear Power Industry Group with KAERI. SMART is being developed for use as an energy source for small-scale power generation and seawater desalination. Although the design of SMART is based on the current pressurized water reactor technology, new technologies such as enhanced safety, and passive safety have been applied, and system simplification and modularization, innovations in manufacturing and installation technologies have been implemented culminating in a design that has enhanced safety and economy, and is environment -friendly. In this paper described the preliminary design of the nuclear Fuel for this SMART, the design concept and the characteristics of SMART Fuel. In specially this paper describe the optimization of grid span adjustment to improve the thermal performance of the SMART Fuel as well as to improve the seismic resistance performance of the SMART Fuel, it is not easy to improve the both performance simultaneously because of design parameter of each performance inversely proportional. SMART Fuel enable to extra-long extended fuel cycle length and resistance of proliferation, enhanced safety, improved economics and reduced nuclear waste

  14. Preliminary Iron Distribution on Vesta

    Science.gov (United States)

    Mittlefehldt, David W.; Mittlefehldt, David W.

    2013-01-01

    The distribution of iron on the surface of the asteroid Vesta was investigated using Dawn's Gamma Ray and Neutron Detector (GRaND) [1,2]. Iron varies predictably with rock type for the howardite, eucrite, and diogenite (HED) meteorites, thought to be representative of Vesta. The abundance of Fe in howardites ranges from about 12 to 15 wt.%. Basaltic eucrites have the highest abundance, whereas, lower crustal and upper mantle materials (cumulate eucrites and diogenites) have the lowest, and howardites are intermediate [3]. We have completed a mapping study of 7.6 MeV gamma rays produced by neutron capture by Fe as measured by the bismuth germanate (BGO) detector of GRaND [1]. The procedures to determine Fe counting rates are presented in detail here, along with a preliminary distribution map, constituting the necessary initial step to quantification of Fe abundances. We find that the global distribution of Fe counting rates is generally consistent with independent mineralogical and compositional inferences obtained by other instruments on Dawn such as measurements of pyroxene absorption bands by the Visual and Infrared Spectrometer (VIR) [4] and Framing Camera (FC) [5] and neutron absorption measurements by GRaND [6].

  15. Preliminary assessment of Ignitor performances

    Energy Technology Data Exchange (ETDEWEB)

    Johner, J

    2000-04-01

    Thermal equilibrium O-D calculations are shown to give useful information in the case of non-stationary discharges if a proper generalization of the plasma amplification factor Q* is chosen. With this definition, Q*={infinity} corresponds to a plasma state where P{sub {alpha}} P{sub loss}. This approach is used for a preliminary assessment of Ignitor performances. For parabolic density and temperature profiles, it is shown that Q{sup *}={infinity} can be obtained in this machine only for an enhancement factor H{sub L} with respect to ITER-97P(th) scaling law of the energy confinement time of the order of 1.9. Using ITER-FEAT assumptions for the density and temperature profiles, it is shown that Q{sup *}={infinity} can be obtained in H-mode with IPB98(y,2) scaling of the energy confinement time. Analysis of the reference operating point of Ignitor proposed by Coppi et al. shows that their alpha power and energy content can be reproduced only with peaked density and temperature profiles. With such profiles, Q{sup *}={infinity} still requires an enhancement factor H{sub L} of 1.44. (author)

  16. Stardust Interstellar Preliminary Examination (ISPE)

    Science.gov (United States)

    Westphal, A. J.; Allen, C.; Bajt, S.; Basset, R.; Bastien, R.; Bechtel, H.; Bleuet, P.; Borg, J.; Brenker F.; Bridges, J.

    2009-01-01

    In January 2006 the Stardust sample return capsule returned to Earth bearing the first solid samples from a primitive solar system body, C omet 81P/Wild2, and a collector dedicated to the capture and return o f contemporary interstellar dust. Both collectors were approximately 0.1m(exp 2) in area and were composed of aerogel tiles (85% of the co llecting area) and aluminum foils. The Stardust Interstellar Dust Col lector (SIDC) was exposed to the interstellar dust stream for a total exposure factor of 20 m(exp 2-) day during two periods before the co metary encounter. The Stardust Interstellar Preliminary Examination ( ISPE) is a three-year effort to characterize the collection using no ndestructive techniques. The ISPE consists of six interdependent proj ects: (1) Candidate identification through automated digital microsco py and a massively distributed, calibrated search (2) Candidate extr action and photodocumentation (3) Characterization of candidates thro ugh synchrotronbased FourierTranform Infrared Spectroscopy (FTIR), S canning XRay Fluoresence Microscopy (SXRF), and Scanning Transmission Xray Microscopy (STXM) (4) Search for and analysis of craters in f oils through FESEM scanning, Auger Spectroscopy and synchrotronbased Photoemission Electron Microscopy (PEEM) (5) Modeling of interstell ar dust transport in the solar system (6) Laboratory simulations of h ypervelocity dust impacts into the collecting media

  17. Preliminary nuclear decommissioning cost study

    International Nuclear Information System (INIS)

    Sissingh, R.A.P.

    1981-04-01

    The decommissioning of a nuclear power plant may involve one or more of three possible options: storage with surveillance (SWS), restricted site release (RSR), and unrestricted site use(USU). This preliminary study concentrates on the logistical, technical and cost aspects of decommissioning a multi-unit CANDU generating station using Pickering GS as the reference design. The procedure chosen for evaluation is: i) removal of the fuel and heavy water followed by decontamination prior to placing the station in SWS for thiry years; ii) complete dismantlement to achieve a USU state. The combination of SWS and USU with an interim period of surveillance allows for radioactive decay and hence less occupational exposure in achieving USU. The study excludes the conventional side of the station, assumes waste disposal repositories are available 1600 km away from the station, and uses only presently available technologies. The dismantlement of all systems except the reactor core can be accomplished using Ontario Hydro's current operating, maintenance and construction procedures. The total decommissioning period is spread out over approximately 40 years, with major activities concentrated in the first and last five years. The estimated dose would be approximately 1800 rem. Overall Pickering GS A costs would be $162,000,000 (1980 Canadian dollars)

  18. Original Article PRELIMINARY BIOAUTOGRAPHIC ANALYSIS OF ...

    African Journals Online (AJOL)

    PRELIMINARY BIOAUTOGRAPHIC ANALYSIS OF THE SEEDS OF GLYPHAEA BREVIS. (SPRENG) MONACHINO FOR ANTIOXIDANT AND ANTIBACTERIAL PRINCIPLES. Michael Lahai1, Tiwalade Adewale Olugbade2. 1Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, College of Medicine ...

  19. Preliminary Phytochemical and Physicochemical Characterization of ...

    African Journals Online (AJOL)

    Purpose: To carry out phytochemical and physicochemical studies on the leaves of Gynura segetum. Methods: Preliminary phytochemical and physicochemical studies using chromatographic techniques,were carried out, Parameters evaluated include ash value, loss on drying and extractive value, amongst others.

  20. Preliminary Analysis of Reinforced Concrete Waffle Walls

    National Research Council Canada - National Science Library

    Shugar, Theodore

    1997-01-01

    A preliminary analytical method based upon modified plate bending theory is offered for structural analysis of a promising new construction method for walls of small buildings and residential housing...

  1. Preliminary design data package. Appendix C

    Energy Technology Data Exchange (ETDEWEB)

    1979-07-25

    The design requirements, design philosophy, method and assumptions, and preliminary computer-aided design of the Near-Term Hybrid Vehicle including its electric and heat power units, control equipment, transmission system, body, and overall vehicle characteristics are presented. (LCL)

  2. Preliminary materials assessment in solar demonstration systems

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, C. F.

    1978-11-01

    A preliminary assessment of materials performance in solar demonstration system are reviewed from published literature and limited service experience. The review is a summary of the solar demonstration systems and the materials used in the collector and transport systems.

  3. Preliminary engineering cost trends for highway projects.

    Science.gov (United States)

    2011-10-21

    Preliminary engineering (PE) for a highway project encompasses two efforts: planning to minimize the physical, social, and human environmental impacts of projects and engineering design to deliver the best alternative. PE efforts begin years in advan...

  4. Dissociation - a preliminary contextual model

    Directory of Open Access Journals (Sweden)

    C Krüger

    2007-02-01

    Full Text Available Background. The Diagnostic and Statistical Manual of Mental Disorders (DSM system has certain limitations when applied to two South African examples of dissociation, because it is descriptive (non-explanatory and focuses on intrapsychic (non-communal processes. Even the existing Western explanatory models of dissociation fail to accommodate fully the communal aspects of dissociation in our South African context. Objectives and methods. The aim was to explore an expanded perspective on dissociation that does not limit it to an intrapsychic phenomenon, but that accounts for the interrelatedness of individuals within their social context. Auto-ethnography was used. In this article a collective, socially orientated, contextual hermeneutic was applied to two local examples of dissociation. Three existing Western models were expanded along multicontextual, collective lines, for them to be more useful in the pluralistic South African context. Results. This preliminary contextual model of dissociation includes a person’s interpersonal, socio-cultural, and spiritual contexts, in addition to the intrapsychic context. Dissociation is considered to be a normal information-processing tool that maintains balanced, coherent selves-in-society, i.e. individuals connected to each other. In the South African context dissociation appears mostly as a normal phenomenon and seldom as a sign of mental illness. Dissociation is pivotal for the normal construction of individual and communal identities in the face of conflicting sets of information from various contexts. Dissociation may help individuals or communities to survive in a world of conflicting messages, where conflict is often interpersonal/cultural/societal in nature, rather than primarily intrapsychic. Conclusions. This model should be developed and evaluated further. Such evaluation would require suitable new local terminology.

  5. Sensitivity to Pain Traumatization Scale: development, validation, and preliminary findings

    Directory of Open Access Journals (Sweden)

    Katz J

    2017-05-01

    Full Text Available Joel Katz,1,2 Samantha R Fashler,1 Claire Wicks,1 M Gabrielle Pagé,3 Kaley M Roosen,1 Valery Kleiman,1 Hance Clarke2 1Department of Psychology, York University, 2Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, ON, 3Centre de recherche du Centre hospitalier de l’Université de Montréal (CRCHUM, Montreal, QC, Canada Background: This article reports three studies describing the development and validation of the 12-item Sensitivity to Pain Traumatization Scale (SPTS-12. SPT refers to the anxiety-related cognitive, emotional, and behavioral reactions to pain that resemble the features of a traumatic stress reaction.Methods: In Study 1, a preliminary set of 79 items was administered to 116 participants. The data were analyzed by using combined nonparametric and parametric item response theory resulting in a 12-item scale with a one-factor structure and good preliminary psychometric properties. Studies 2 and 3 assessed the factor structure and psychometric properties of the SPTS-12 in a community sample of 823 participants (268 with chronic pain and 555 pain-free and a clinical sample of 345 patients (126 with chronic post-surgical pain, 92 with other nonsurgical chronic pain, and 127 with no chronic pain at least 6 months after undergoing coronary artery bypass graft surgery, respectively. Results: The final SPTS-12 derived from Study 1 comprised 12 items that discriminated between individuals with different levels of SPT, with the overall scale showing good to very good reliability and validity. The results from Studies 2 and 3 revealed a one-factor structure for chronic pain and pain-free samples, excellent reliability and concurrent validity, and moderate convergent and discriminant validity. Conclusion: The results of the three studies provide preliminary evidence for the validity and reliability of the SPTS-12. Keywords: chronic pain, chronic post-surgical pain, trauma, psychology, scale development

  6. Time domain simulations of preliminary breakdown pulses in natural lightning.

    Science.gov (United States)

    Carlson, B E; Liang, C; Bitzer, P; Christian, H

    2015-06-16

    Lightning discharge is a complicated process with relevant physical scales spanning many orders of magnitude. In an effort to understand the electrodynamics of lightning and connect physical properties of the channel to observed behavior, we construct a simulation of charge and current flow on a narrow conducting channel embedded in three-dimensional space with the time domain electric field integral equation, the method of moments, and the thin-wire approximation. The method includes approximate treatment of resistance evolution due to lightning channel heating and the corona sheath of charge surrounding the lightning channel. Focusing our attention on preliminary breakdown in natural lightning by simulating stepwise channel extension with a simplified geometry, our simulation reproduces the broad features observed in data collected with the Huntsville Alabama Marx Meter Array. Some deviations in pulse shape details are evident, suggesting future work focusing on the detailed properties of the stepping mechanism. Preliminary breakdown pulses can be reproduced by simulated channel extension Channel heating and corona sheath formation are crucial to proper pulse shape Extension processes and channel orientation significantly affect observations.

  7. Preliminary results of the first paleontologic investigations in Uruguayan Antarctica

    International Nuclear Information System (INIS)

    Perea, D.; Masquelin, E.; Verde, M.; Querequiz, R.

    1998-01-01

    Preliminary results of the first Uruguayan paleontollogic and biostratigraphical investigations in Antartica are presented. The field work was performed in fildes Peninsula, King George Island, near Uruguayan station Base Cientifica Antarctica Artigas.Some fossiliferous outcrops were geologic and paleontologically analyzed, among them Fossil Hills, situated in the center part of the peninsula, in front of Ardley Island, between the chinese and chilean stations.This hill is composed of fossil bearing piroclastic and epiclastic rocks, assigned to the fossil Hill Fm. Vegetal remains(petrified wood and leaf impronts) were observed and collected in this unit and it is remarkable the presence of Nothofagus sp. and invertebrate trace fossils, Cochlichmus isp and Helminthopsis isp.The depositional environment deduced from the fossil association in lacustrine, under a warm and humid climate.In the same deposits, other investigators have collected aquatic and ratite bird trace fossils. Paleontologic evidence is not contradictory with the Eocene age previously proposed for the studied deposits. (author)

  8. Preliminary study of varietal susceptibility to sulfur dioxide

    International Nuclear Information System (INIS)

    Miller, J.E.; Xerikos, P.B.

    1976-01-01

    The injury response of plants to air pollutants, such as sulfur dioxide, is known to vary in severity and type for different varieties or cultivars of a species. Differences in the susceptibility of soybean varieties to sulfur dioxide have previously been noted, but sufficient information is not available concerning the sulfur dioxide resistance of varieties commonly grown in the Midwest. Results are reported from preliminary experiments concerning acute sulfur dioxide effects on 12 soybean varieties. The injury symptoms ranged from cream colored necrotic lesions (generally on younger leaves) to a reddish brown necrotic stipling (on older leaves). Differences in the severity of symptom development for the varieties was evident on both the younger and older leaves. No injury was apparent with three of the varieties

  9. TSUNAMI PROPAGATION ALONG TAGUS ESTUARY (LISBON, PORTUGAL PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    M. A. Viana-Baptista

    2006-01-01

    Full Text Available In this study we present preliminary results of flood calculation along Tagus Estuary, a catastrophic event that happened several times in the past, as described in historical documents, and that constitutes one of the major risk sources for Lisbon coastal area. To model inundation we used Mader’s SWAN model for the open ocean propagation with a 2 km grid, and Imamura’s TSUN2 with a 50 m grid covering the entire estuary. The seismic source was computed with the homogeneous elastic half space approach. Modelling results agree with historical reports. Synthetic flood areas correspond to the sites where there are morphological and sedimentary evidences of two known major events that stroke Lisbon: 1531-01-26 and 1755-11-01 tsunamis.

  10. The iron swords from the necropolis of Son Pellisser; preliminary advance

    Directory of Open Access Journals (Sweden)

    Agustín Fernández Mártinez

    2016-11-01

    Full Text Available This paper submits the iron swords from the necropolis of Son Pellisser (Calvià-Majorca. Although the materials that we find are numerous and still under research offer a preliminary study about three imported swords, found in burial objects, also their possible origin and way of introduction on the island. These weapons could be the first archaeological evidence that the Balearic mercenaries participated in the Wars of Sicily, between Carthaginians and Greeks, from the fifth century BC.

  11. Hydrothermal Liquefaction Treatment Preliminary Hazard Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Lowry, Peter P.; Wagner, Katie A.

    2015-08-31

    A preliminary hazard assessment was completed during February 2015 to evaluate the conceptual design of the modular hydrothermal liquefaction treatment system. The hazard assessment was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. This analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affecting the public.

  12. Evidence and evidence gaps in tinnitus therapy

    Science.gov (United States)

    Hesse, Gerhard

    2016-01-01

    A nearly endless number of procedures has been tried and in particular sold for the treatment of tinnitus, unfortunately they have not been evaluated appropriately in an evidence-based way. A causal therapy, omitting the tinnitus still does not exist, actually it cannot exist because of the various mechanisms of its origin. However or perhaps because of that, medical interventions appear and reappear like fashion trends that can never be proven by stable and reliable treatment success. This contribution will discuss and acknowledge all current therapeutic procedures and the existing or non-existing evidence will be assessed. Beside external evidence, the term of evidence also encompasses the internal evidence, i.e. the experience of the treating physician and the patient’s needs shall be included. While there is no evidence for nearly all direct procedures that intend modulating or stimulating either the cochlea or specific cervical regions such as the auditory cortex, there are therapeutic procedures that are acknowledged in clinical practice and have achieved at least a certain degree of evidence and generate measurable effect sizes. Those are in particular habituation therapy and psychotherapeutic measures, especially if they are combined with concrete measures for improved audio perception (hearing aids, CI, hearing therapies). PMID:28025604

  13. Preliminary designs: passive solar manufactured housing. Technical status report

    Energy Technology Data Exchange (ETDEWEB)

    1980-05-12

    The criteria established to guide the development of the preliminary designs are listed. Three preliminary designs incorporating direct gain and/or sunspace are presented. Costs, drawings, and supporting calculations are included. (MHR)

  14. Preliminary Evaluation of Some Engineering Geological Properties ...

    African Journals Online (AJOL)

    Preliminary Evaluation of Some Engineering Geological Properties of Soils in the New Yenagoa Town, Bayelsa State, Central Niger Delta. ... Therefore, adequate attention should be given to the likely physical environmental degradation of river bank failure and liquefaction condition that may evolve as a result of ...

  15. Preliminary investigation into the possible endocrine disrupting ...

    African Journals Online (AJOL)

    ... reduction (p<0.05). The estrogen level in the female rats showed a general significant increase (p<0.05) in all the groups when compared with the female control group. This preliminary result suggest that Bonny-Light crude oil may have the potential to alter reproductive activity and hence a possible endocrine disruptor.

  16. Phytochemical Screening and Preliminary Evaluation of Analgesic ...

    African Journals Online (AJOL)

    In this study, the methanolic root extract of Cissus polyantha was subjected to preliminary phytochemical screening, analgesic and anti-inflammatory studies. Phytochemical studies was carried out using standard phytochemical protocol while the analgesic studies was carried out using acetic acid-induced writhing tests in ...

  17. A DESCRIPTIVE INDONESIAN GRAMMAR--PRELIMINARY EDITION.

    Science.gov (United States)

    DYEN, ISIDORE

    THIS PRELIMINARY EDITION COMPRISES A DESCRIPTIVE GRAMMAR OF INDONESIAN (BAHASA INDONESIA), THE OFFICIAL LANGUAGE OF THE REPUBLIC OF INDONESIA. THE THREE SECTIONS--PHONOLOGY, SYNTAX, AND MORPHOLOGY--PRESENT A COMPREHENSIVE LINGUISTIC ANALYSIS OF INDONESIAN, WITH OCCASIONAL CONTRASTIVE REFERENCE TO MALAY, JAVANESE, SUNDANESE, AND SUMATRAN. THIS…

  18. Preliminary investigations of piezoelectric based LED luminary

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Andersen, Michael A. E.; Meyer, Kaspar Sinding

    2011-01-01

    This paper presents a preliminary study of PT (Piezoelectric Transformer) based SMPS’s (Switch Mode Power Supplies) for LED luminary. The unique properties of PTs (efficiency, power density and EMI) make them highly suitable for this application. Power stage topologies, rectifiers circuits...

  19. Preliminary investigation into the possible endocrine disrupting ...

    African Journals Online (AJOL)

    JTEkanem

    Preliminary investigation into the possible endocrine disrupting activity of Bonny light crude oil contaminated - diet on ... rats (twenty male and twenty five females) were expose to Bonny –light crude oil contaminated diet at concentrations of 1%, 5% and 10% .... also being implicated in possessing antiestrogenic activity9.

  20. preliminary multidomain modelling and simulation study

    African Journals Online (AJOL)

    user

    PRELIMINARY MULTIDOMAIN MODELLING AND SIMULATION STUDY OF A. HORIZONTAL AXIS WIND TURBINE (HAWT) TOWER VIBRATION. I. lliyasu1, I. Iliyasu2, I. K. Tanimu3 and D. O Obada4. 1,4 DEPARTMENT OF MECHANICAL ENGINEERING, AHMADU BELLO UNIVERSITY, ZARIA, KADUNA STATE. NIGERIA.

  1. Resumption Of Sexual Relationship After Childbirth: Preliminary ...

    African Journals Online (AJOL)

    Resumption Of Sexual Relationship After Childbirth: Preliminary Observations On Husband\\'s Attitude. ... An open-ended questionnaire developed by the authors was used to elicit information on relevant aspects of husbands' reproductive behaviour. We found that husbands' preferred time of resumption of sexual ...

  2. Preliminary characterization of slow growing rhizobial strains ...

    African Journals Online (AJOL)

    In this paper, we did some preliminary characterization of six slow growing rhizobial strains, isolated from Retama monosperma (L.) Boiss. root nodules sampled from 3 sites along the coast of Oran (CapeFalcon, Bousfer and MersElHadjadj) in Northwestern Algeria. Results of this study showed that all strains had a very ...

  3. Preliminary characterization of Rhizobium strains isolated from ...

    African Journals Online (AJOL)

    SERVER

    2008-03-18

    Mar 18, 2008 ... Rhizobium strains from chickpea nodules exercised an antagonism against Ascocyhta rabiei the agent of ascocyhta blight disease of chickpea. Key words: Rhizobium, chickpea (Cicer arietinum L.), preliminary characterization. INTRODUCTION. Chickpea (Cicer arietinum L.) is a major source of protein.

  4. Preliminary Findings on Rural Homelessness in Ohio.

    Science.gov (United States)

    First, Richard J.; And Others

    This report is designed to present preliminary findings from the first comprehensive study of rural homelessness in the United States. The study was conducted during the first 6 months of 1990, and data were collected from interviews with 921 homeless adults in 21 randomly selected rural counties in Ohio. The sample counties represent 26% of the…

  5. Preliminary tests of the electrostatic plasma accelerator

    Science.gov (United States)

    Aston, G.; Acker, T.

    1990-01-01

    This report describes the results of a program to verify an electrostatic plasma acceleration concept and to identify those parameters most important in optimizing an Electrostatic Plasma Accelerator (EPA) thruster based upon this thrust mechanism. Preliminary performance measurements of thrust, specific impulse and efficiency were obtained using a unique plasma exhaust momentum probe. Reliable EPA thruster operation was achieved using one power supply.

  6. Combustion synthesis and preliminary luminescence studies of ...

    Indian Academy of Sciences (India)

    6, October 2015, pp. 1527–1531. c Indian Academy of Sciences. Combustion synthesis and preliminary luminescence studies of. LiBaPO4 : Tb. 3+ phosphor. C B PALAN1,∗, N S BAJAJ1, ... MS received 28 April 2015; accepted 8 June 2015. Abstract. ... In CW-OSL mode its sensitivity for beta expo- sure was found to be ...

  7. The Adaptation Gap Report - a Preliminary Assessment

    DEFF Research Database (Denmark)

    Alverson, Keith; Olhoff, Anne; Noble, Ian

    This first Adaptation Gap report provides an equally sobering assessment of the gap between adaptation needs and reality, based on preliminary thinking on how baselines, future goals or targets, and gaps between them might be defined for climate change adaptation. The report focuses on gaps in de...

  8. Preliminary Phytochemical, Antimicrobial and Acute Toxicity Studies ...

    African Journals Online (AJOL)

    Jane

    2010-10-11

    Oct 11, 2010 ... Preliminary Phytochemical, Antimicrobial and Acute. Toxicity Studies of the Stem, bark and the Leaves of a cultivated Syzygium cumini Linn. (Family: Myrtaceae) in. Nigeria. *Ugbabe, G.E1, *Ezeunala, M.N2, Edmond, I.N3, Apev, J1 and Salawu, O.A3. 1Medicinal Plant Research and Traditional Medicine ...

  9. Preliminary Toxicological Screening of Ichthyotoxic Compound of ...

    African Journals Online (AJOL)

    Moringa oleifera is an indigenous tree growing in Southwestern Nigeria for food and medicinal property. Therefore this study evaluates the preliminary toxicological screening of ichthyotoxic compounds in Moringa oleifera to freshwater fish, Oreochromis niloticus fingerlings. The morphological parts such as leaf, seed, ...

  10. 32 CFR 644.30 - Preliminary real estate work.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Preliminary real estate work. 644.30 Section 644... PROPERTY REAL ESTATE HANDBOOK Project Planning Military (army and Air Force) and Other Federal Agencies § 644.30 Preliminary real estate work. (a) Preliminary real estate work is defined as that action taken...

  11. NATIONAL SCIENCE FOUNDATION. Preliminary Observations on Indirect Costs for Research

    Science.gov (United States)

    2017-05-24

    NATIONAL SCIENCE FOUNDATION Preliminary Observations on Indirect Costs for Research Statement of John Neumann, Director...Representatives May 24, 2017 NATIONAL SCIENCE FOUNDATION Preliminary Observations on Indirect Costs for Research What GAO Found GAO’s preliminary...analysis of National Science Foundation (NSF) data indicates that for fiscal years 2000 through 2016, indirect costs on NSF awards ranged from 16

  12. The Van Fault, Eastern Turkey: A Preliminary Geological Slip Rate

    Science.gov (United States)

    Mackenzie, D.; Elliott, J. R.; Altunel, E.; Kurban, Y.; Walker, R. T.; Parsons, B.

    2014-12-01

    We present a preliminary quaternary slip-rate study on the Van fault, the source of the 2011 Mw7.1 reverse-slip earthquake which caused heavy damage to the cities of Van and Ercis, eastern Turkey. From the InSAR solution, we see a strong depth cut-off at 10km depth, above which there was no slip on the fault. We have carried out an investigation of the geomorphological expression of the fault in quaternary material, to determine whether the fault reaches the surface and, if so, whether this upper section could fail in an earthquake. On the western segment of the Van fault, we observe quaternary scarps coincident with the surface projection of the fault segment identified by InSAR, which displace quaternary alluvial fan and lake-bed deposits. These are coincident with the observation of fault gouge in quaternary deposits at a road cutting, providing evidence for a fault reaching the surface and suggesting that the upper section is capable of rupturing seismically. We use structure-from-motion photogrammetry, differential GPS and terrestrial LiDAR to determine offsets on two generations of fault scarps, and the creep offsets from the period following the earthquake. Preliminary radiocarbon and OSL dates from two uplifted terrace surfaces allow us to estimate a late quaternary geological slip-rate for the fault. Following the GPS and InSAR solution of Dogan et al. 2014 (GRL v41,i7), we also present field evidence and satellite image observations confirming the presence of a splay fault within the northern suburbs of Van city, which experienced creep following the 2011 earthquake. This fault is observed to be particularly evident in the early high resolution satellite imagery from the declassified CORONA missions, highlighting the potential for these datasets in identifying faults in areas now covered by urban sprawl. It remains unclear whether this fault could fail seismically. The fault which failed in 2011 is a north dipping reverse fault, unmapped prior to the

  13. The Evidence Movement

    DEFF Research Database (Denmark)

    Hansen, Hanne Foss; Rieper, Olaf

    2009-01-01

    The evidence movement and the idea of systematic reviews, defined as summaries of the results of already existing evaluation and research projects, have gained considerable support in recent years as many international as well as national evidence-producing organizations have been established....... This article analyses how the idea is practised in the areas of health, social welfare and education and shows that evidence-producing organizations work differently. Some subscribe to the hierarchy of evidence, others to a typology of evidence. The consequences of these variations are discussed....

  14. Exploratory shaft facility preliminary designs - Paradox Basin. Technical report

    International Nuclear Information System (INIS)

    1983-09-01

    The purpose of the Preliminary Design Report, Paradox Basin, is to provide a description of the preliminary design for an Exploratory Shaft Facility in the Paradox Basin, Utah. This issue of the report describes the preliminary design for constructing the exploratory shaft using the Large Hole Drilling Method of construction and outlines the preliminary design and estimates of probable construction cost. The Preliminary Design Report is prepared to complement and summarize other documents that comprise the design at the preliminary stage of completion, December 1982. Other design documents include drawings, cost estimates and schedules. The preliminary design drawing package, which includes the construction schedule drawing, depicts the descriptions in this report. For reference, a list of the drawing titles and corresponding numbers is included in the Appendix. The report is divided into three principal sections: Design Basis, Facility Description, and Construction Cost Estimate. 30 references

  15. Exploratory shaft facility preliminary designs - Gulf Interior Region salt domes

    International Nuclear Information System (INIS)

    1983-09-01

    The purpose of the Preliminary Design Report, Gulf Interior Region, is to provide a description of the preliminary design for an Exploratory Shaft Facility on the Richton Dome, Mississippi. This issue of the report describes the preliminary design for constructing the exploratory shaft using the Large Hole Drilling method of construction and outlines the preliminary design and estimates of probable construction cost. The Preliminary Design Report is prepared to complement and summarize other documents that comprise the design at the preliminary stage of completion, December 1982. Other design documents include drawings, cost estimates and schedules. The preliminary design drawing package, which includes the construction schedule drawing, depicts the descriptions in this report. For reference, a list of the drawing titles and corresponding numbers are included in the Appendix. The report is divided into three principal sections: Design Basis, Facility Description and Construction Cost Estimate

  16. Preliminary results from NOAMP deep drifting floats

    International Nuclear Information System (INIS)

    Ollitrault, M.

    1989-01-01

    This paper is a very brief and preliminary outline of first results obtained with deep SOFAR floats in the NOAMP area. The work is now going toward more precise statistical estimations of mean and variable currents, together with better tracking to resolve submesoscales and estimate diffusivities due to mesoscale and smaller scale motions. However the preliminary results confirm that the NOAMP region (and surroundings) has a deep mesoscale eddy field that is considerably more energetic that the mean field (r.m.s. velocities are of order 5 cm s -1 ), although both values are diminished compared to the western basin. A data report containing trajectories and statistics is scheduled to be published by IFREMER in the near future. The project main task is to especially study the dispersion of radioactive substances

  17. Rare earth optogalvanic spectroscopy: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Destro, Marcelo G.; Neri, Jose W.; Rodrigues, Nicolau A.S.; Silveira, Carlos A.B.; Riva, Rudimar [Instituto de Estudos Avancados (IEAv/EFO), Sao Jose dos Campos, SP (Brazil). Div. de Fotonica]. E-mail: destro@ieav.cta.br; Victor, Alessandro R. [Instituto Tecnologico de Aeronautica (ITA), Sao Jose dos Campos, SP (Brazil)

    2008-07-01

    The IEAv has special interest in the studies of rare earth isotope applications in laser medium and integrated optics as well as aerospace research. We are starting to work with Ytterbium, Erbium, Dysprosium and Neodymium laser selective photoionization research. This paper describes the preliminary results of emission and optogalvanic spectroscopy obtained from a Neodymium hollow cathode lamps. Furthermore these results were used to setup our laser systems to work to leads a Nd isotopes selective laser photoionization. (author)

  18. Preliminary investigations of piezoelectric based LED luminary

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Andersen, Michael A. E.; Meyer, Kaspar Sinding

    2011-01-01

    This paper presents a preliminary study of PT (Piezoelectric Transformer) based SMPS’s (Switch Mode Power Supplies) for LED luminary. The unique properties of PTs (efficiency, power density and EMI) make them highly suitable for this application. Power stage topologies, rectifiers circuits, modul....... The prototype constitutes a light source equivalent to the 40 W incandescent bulb. Experimental results shows, that the prototype are capable of ZVS and dimming (the later trough use of burst mode control)....

  19. Preliminary model for core/concrete interactions

    International Nuclear Information System (INIS)

    Murfin, W.B.

    1977-08-01

    A preliminary model is described for computing the rate of penetration of concrete by a molten LWR core. Among the phenomena included are convective stirring of the melt by evolved gases, admixture of concrete decomposition products to the melt, chemical reactions, radiative heat loss, and variation of heat transfer coefficients with local pressure. The model is most applicable to a two-phase melt (metallic plus oxidic) having a fairly high metallic content

  20. [Ethnic entrepreneurship in Montreal: some preliminary results].

    Science.gov (United States)

    Juteau, D; Daviau-guay, J; Moallem, M

    1992-01-01

    "This research note presents a first sketch of a study we are undertaking on ethnic entrepreneurship [in Montreal]. It details first of all our theoretical framework and then presents some preliminary results. For this research, we are studying various ethnic groups, those in the majority as well as the minority. For each of them, we will analyze the impact that immigration status, sex, the industrial sector and urban context play on entrepreneurial activity." (SUMMARY IN ENG AND SPA) excerpt

  1. Life cycle analysis in preliminary design stages

    OpenAIRE

    Agudelo , Lina-Maria; Mejía-Gutiérrez , Ricardo; Nadeau , Jean-Pierre; PAILHES , Jérôme

    2014-01-01

    International audience; In a design process the product is decomposed into systems along the disciplinary lines. Each stage has its own goals and constraints that must be satisfied and has control over a subset of design variables that describe the overall system. When using different tools to initiate a product life cycle, including the environment and impacts, its noticeable that there is a gap in tools that linked the stages of preliminary design and the stages of materialization. Differen...

  2. PLANT COMMUNITIES OF ALBANIA - A PRELIMINARY OVERVIEW

    Directory of Open Access Journals (Sweden)

    J, RODWELL

    2002-01-01

    Full Text Available The phytosociological analysis of Albania was initiated by F. Markgraf in the 30ies, but still remains incomplete. This is a preliminary list of the plant communities resulting from the literature and from field research carried out during the last years and may represent a first contribution for further research. Many communities are described only by dominant species, other are quoted as nomina nuda. Some further syntaxa. probably present in the study area, are added.

  3. PLANT COMMUNITIES OF ALBANIA - A PRELIMINARY OVERVIEW

    Directory of Open Access Journals (Sweden)

    J. DRING

    2002-04-01

    Full Text Available The phytosociological analysis of Albania was initiated by F. Markgraf in the 30ies, but still remains incomplete. This is a preliminary list of the plant communities resulting from the literature and from field research carried out during the last years and may represent a first contribution for further research. Many communities are described only by dominant species, other are quoted as nomina nuda. Some further syntaxa. probably present in the study area, are added.

  4. Preliminary safety analysis methodology for the SMART

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Kyoo Hwan; Chung, Y. J.; Kim, H. C.; Sim, S. K.; Lee, W. J.; Chung, B. D.; Song, J. H. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    This technical report was prepared for a preliminary safety analysis methodology of the 330MWt SMART (System-integrated Modular Advanced ReacTor) which has been developed by Korea Atomic Energy Research Institute (KAERI) and funded by the Ministry of Science and Technology (MOST) since July 1996. This preliminary safety analysis methodology has been used to identify an envelope for the safety of the SMART conceptual design. As the SMART design evolves, further validated final safety analysis methodology will be developed. Current licensing safety analysis methodology of the Westinghouse and KSNPP PWRs operating and under development in Korea as well as the Russian licensing safety analysis methodology for the integral reactors have been reviewed and compared to develop the preliminary SMART safety analysis methodology. SMART design characteristics and safety systems have been reviewed against licensing practices of the PWRs operating or KNGR (Korean Next Generation Reactor) under construction in Korea. Detailed safety analysis methodology has been developed for the potential SMART limiting events of main steam line break, main feedwater pipe break, loss of reactor coolant flow, CEA withdrawal, primary to secondary pipe break and the small break loss of coolant accident. SMART preliminary safety analysis methodology will be further developed and validated in parallel with the safety analysis codes as the SMART design further evolves. Validated safety analysis methodology will be submitted to MOST as a Topical Report for a review of the SMART licensing safety analysis methodology. Thus, it is recommended for the nuclear regulatory authority to establish regulatory guides and criteria for the integral reactor. 22 refs., 18 figs., 16 tabs. (Author)

  5. Appropriateness of administration of nasogastric medication and preliminary intervention

    Directory of Open Access Journals (Sweden)

    Zhou Q

    2012-11-01

    Full Text Available Ling-Ling Zhu,1 Ling-Cheng Xu,2 Hui-Qin Wang,3 Jing-Fen Jin,3 Hua-Fen Wang,3 Quan Zhou21Cadre Department, 2Department of Pharmacy, 3Division of Nursing, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, ChinaAbstract: A utilization study was performed in a 2200-bed tertiary care teaching hospital. Data mining was performed on all nasogastric medication prescriptions for patients hospitalized in 2011. Nurses were interviewed by questionnaire. A PDCA (Plan-Do-Check-Act cycle was used for continuous quality improvement. The proportion of patients with nasogastric tubes (NGT was 3.2%. A large number of medical orders (n  6261 involved nasogastric medications with a package insert particularly noting that they should not be crushed or opened (group 1 or medications without a specific formulation recommendation in the package insert but having evidence discouraging NGT dosing (group 2. Of the nasogastrically administered sustained-release or controlled-release formulations, a sustained-release sodium valproate tablet formulation was the most prescribed drug and a sustained-release 2.5 mg felodipine tablet was prescribed with the highest proportion of NGT dosing [NGT/(NGT  oral  12.3%]. Among the nasogastrically administered enteric-coated formulations, a myrtol-standardized enteric-coated capsule formulation was the most prescribed drug and a pantoprazole tablet formulation was prescribed with the highest proportion of NGT dosing [NGT/(NGT  oral  19.3%]. Proportions of NGT dosing for amiodarone and carbamazepine (group 2 were 4.8% and 6.3%, respectively. The percentage of nurses with adequate knowledge about pharmaceutical dosage formulations was 60%. The rate of answering correctly as to whether medications in group 1 could be crushed or opened was only 30%. Awareness of evidence discouraging NGT dosing of medications in group 2 was zero. Most nurses (90% left physicians and

  6. Appropriateness of administration of nasogastric medication and preliminary intervention

    Science.gov (United States)

    Zhu, Ling-Ling; Xu, Ling-Cheng; Wang, Hui-Qin; Jin, Jing-Fen; Wang, Hua-Fen; Zhou, Quan

    2012-01-01

    A utilization study was performed in a 2200-bed tertiary care teaching hospital. Data mining was performed on all nasogastric medication prescriptions for patients hospitalized in 2011. Nurses were interviewed by questionnaire. A PDCA (Plan-Do-Check-Act) cycle was used for continuous quality improvement. The proportion of patients with nasogastric tubes (NGT) was 3.2%. A large number of medical orders (n = 6261) involved nasogastric medications with a package insert particularly noting that they should not be crushed or opened (group 1) or medications without a specific formulation recommendation in the package insert but having evidence discouraging NGT dosing (group 2). Of the nasogastrically administered sustained-release or controlled-release formulations, a sustained-release sodium valproate tablet formulation was the most prescribed drug and a sustained-release 2.5 mg felodipine tablet was prescribed with the highest proportion of NGT dosing [NGT/(NGT + oral) = 12.3%]. Among the nasogastrically administered enteric-coated formulations, a myrtol-standardized enteric-coated capsule formulation was the most prescribed drug and a pantoprazole tablet formulation was prescribed with the highest proportion of NGT dosing [NGT/(NGT + oral) = 19.3%]. Proportions of NGT dosing for amiodarone and carbamazepine (group 2) were 4.8% and 6.3%, respectively. The percentage of nurses with adequate knowledge about pharmaceutical dosage formulations was 60%. The rate of answering correctly as to whether medications in group 1 could be crushed or opened was only 30%. Awareness of evidence discouraging NGT dosing of medications in group 2 was zero. Most nurses (90%) left physicians and pharmacists with the entire responsibility for knowledge and decision-making concerning route of drug administration. After a 3-month preliminary intervention, irrational medical orders involving nasogastric administration of medications in group 1 were successfully abolished. The rate of answering

  7. What is Evidence? (editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2011-06-01

    Full Text Available Lately, I have been pondering what we really mean when we say “evidence based practice”? In LIS, we all know the definitions that have been proposed (Booth 2000, Eldredge 2000, Crumley and Koufogiannakis 2002, and which have not ever really been challenged. But have we ever said explicitly what qualifies as evidence in this model? The underlying assumption seems to be that evidence is research, hence, we are really talking about research-based practice, but we don’t actually use that term.Higgs and Jones (2000 note that evidence is “knowledge derived from a variety of sources that has been subjected to testing and has found to be credible.” The Oxford English Dictionary states that evidence is “something serving as a proof” (OED, 2011. Neither of these definitions of evidence notes that evidence equals research; research is only one form of evidence. It certainly isn’t the only form of evidence – so what, then, constitutes evidence?Rycroff-Malone et al. (2004 state that that in order for evidence based practice to create a broader evidence base in nursing, “the external, scientific and the internal, intuitive” need to be brought together. The external, scientific is what evidence based practice has been focused on, in the form of scientific research, but Rycroff-Malone et al. note that other elements such as clinical experience, patient experience, and information from the local context also need to be considered.In library and information practice, what are the other forms of evidence we need to consider? I propose that while research evidence is of high importance to our profession and knowledge, LIS practitioners need to first of all consider local evidence. Local evidence is found in our working environment and specific to the context in which we carry out our work. It includes such things as our experiences with patrons in particular contexts, and what we observe to work in such situations, assessment of programs

  8. Preliminary Evidences of Biofortification with Iodine of “Carota di Polignano”, An Italian Carrot Landrace

    Directory of Open Access Journals (Sweden)

    Angelo Signore

    2018-02-01

    Full Text Available The “Carota di Polignano” (Polignano Carrot – PC, Daucus carota L. is a multi-colored landrace, cultivated in the Southern Italy, whose colors range from yellow to purple. Iodine is an essential micronutrient for humans, since it is a key component of thyroid hormones, which regulate the growth and development of the human body. The main source for iodine assumption is represented by diet, but its concentration in the vegetables is usually limited with respect to human needs. To this purpose, two experimental trials (in open field and in greenhouse with a soil-less system were carried out to enrich PC with iodine. Three levels of iodine (control treatment, C – 0 mg·L−1; low, L – 50 mg·L−1; and high, H – 500 mg·L−1, distributed with foliar spray fertilizations (in both open field and greenhouse or with nutrient solution (in greenhouse, at the level of 50 mg·L−1 in the form of KIO3 were compared. In open field, the H treatment showed a biofortification that was double and triple respect to L and C treatments, respectively, without influencing color and biometric parameters, such as the fresh and dry weight of roots and DM percentage. In greenhouse, the biofortification done with foliar spray fertilization followed the same trend of open field, while the biofortification by means of nutrient solution was more effective but reached very high levels that had toxic effects on the plants and could be too high for human nutrition. However, the concentrations of iodine into biofortified carrots in open field can allow to satisfy the recommended daily allowance (RDA by consuming 100 and 200 g of fresh product for the treatment H and L, respectively. Regarding the greenhouse biofortification, the RDA would be satisfied by consuming 200 g of fresh carrots (with the high level of foliar fertilization.

  9. Preliminary evidence on the uptake, use and benefits of the CONSORT-PRO extension.

    Science.gov (United States)

    Mercieca-Bebber, Rebecca; Rouette, Julie; Calvert, Melanie; King, Madeleine T; McLeod, Lori; Holch, Patricia; Palmer, Michael J; Brundage, Michael

    2017-06-01

    This study assessed the uptake of the CONsolidated Standards of Reporting Trials (CONSORT)-Patient-Reported Outcomes (PRO) statement; determined if use of CONSORT-PRO was associated with more complete reporting of PRO endpoints in randomised controlled trials (RCTs) and identified the extent to which high-impact journals publishing RCTs with PRO endpoints endorse CONSORT-PRO. CONSORT-PRO citations were identified by systematically searching Medline, EMBASE and Google from 2013 (year CONSORT-PRO released) to 17 December 2015. RCTs that cited CONSORT-PRO (cases) were compared to a comparable control sample of RCTs in terms of adherence to CONSORT-PRO using t tests. General linear models assessed the relationship between CONSORT-PRO score and key, pre-specified variables. The 100 highest-impact journals that published RCTs with PRO endpoints (2014-2015) were identified via a systematic Medline search. Instructions for authors were reviewed to determine whether journals endorsed CONSORT-PRO. Total CONSORT-PRO scores ranged from 47 to 100% for cases and 25-96% for controls. Cases had significantly higher total CONSORT-PRO scores compared to controls: t = 2.64, p = 0.01. 'Citing CONSORT-PRO', 'journal endorsing CONSORT-PRO' and 'dedicated PRO paper' were significant predictors of higher CONSORT-PRO adherence score: R 2  = 0.48, p CONSORT-PRO in their instructions to authors, seven of these journals published RCTs included as cases in this study. This study demonstrated improved PRO reporting associated with journal endorsement and author use of the CONSORT-PRO extension. Despite growing awareness, more work is needed to promote appropriate use of CONSORT-PRO to improve completeness of reporting; in particular, stronger journal endorsement of CONSORT-PRO.

  10. The Meriden School Climate Survey-Student Version: Preliminary Evidence of Reliability and Validity

    Science.gov (United States)

    Gage, Nicholas A.; Larson, Alvin; Chafouleas, Sandra M.

    2016-01-01

    School climate has been linked with myriad positive student outcomes and the measurement of school climate is widely advocated at the national and state level. However, districts have little guidance about how to define and measure school climate. This study examines the psychometric properties of a district-developed school climate measure that…

  11. Transport and redistribution of Chernobyl fallout radionuclides by fluvial processes: some preliminary evidence

    International Nuclear Information System (INIS)

    Walling, D.E.; Bradley, S.B.

    1988-01-01

    Several measurements of 137 Cs concentrations in suspended sediment transported by the River Severn during the post-Chernobyl period and in recent channel and floodplain deposits along the river emphasise the potential significance of fluvial processes in the transport and concentration of fallout radionuclides. (author)

  12. Preliminary Evidence for Reduced Post-Error Reaction Time Slowing in Hyperactive/Inattentive Preschool Children

    Science.gov (United States)

    Berwid, Olga G.; Halperin, Jeffrey M.; Johnson, Ray E.; Marks, David J.

    2013-01-01

    Background Attention-Deficit/Hyperactivity Disorder has been associated with deficits in self-regulatory cognitive processes, some of which are thought to lie at the heart of the disorder. Slowing of reaction times (RTs) for correct responses following errors made during decision tasks has been interpreted as an indication of intact self-regulatory functioning and has been shown to be attenuated in school-aged children with ADHD. This study attempted to examine whether ADHD symptoms are associated with an early-emerging deficit in post-error slowing. Method A computerized two-choice RT task was administered to an ethnically diverse sample of preschool-aged children classified as either ‘control’ (n = 120) or ‘hyperactive/inattentive’ (HI; n = 148) using parent- and teacher-rated ADHD symptoms. Analyses were conducted to determine whether HI preschoolers exhibit a deficit in this self-regulatory ability. Results HI children exhibited reduced post-error slowing relative to controls on the trials selected for analysis. Supplementary analyses indicated that this may have been due to a reduced proportion of trials following errors on which HI children slowed rather than to a reduction in the absolute magnitude of slowing on all trials following errors. Conclusions High levels of ADHD symptoms in preschoolers may be associated with a deficit in error processing as indicated by post-error slowing. The results of supplementary analyses suggest that this deficit is perhaps more a result of failures to perceive errors than of difficulties with executive control. PMID:23387525

  13. Preliminary evidence for normalization of risk taking by modafinil in chronic cocaine users.

    Science.gov (United States)

    Canavan, Sofija V; Forselius, Erica L; Bessette, Andrew J; Morgan, Peter T

    2014-06-01

    Modafinil, a wake-promoting agent used to treat sleep disorders, is thought to enhance cognition. Although modafinil has shown promise as a pharmacotherapy for the treatment of cocaine dependence, it is unknown to what extent cognitive effects may play a role in such treatment. We examined the effect of modafinil on the Balloon Analogue Risk Task (BART), a behavioral measure in which higher scores are purported to reflect a greater propensity for risk-taking. Thirty cocaine dependent individuals, enrolled in a randomized clinical trial of modafinil 400mg (n=12) versus placebo (n=18), were administered the BART during the second week of inpatient treatment for cocaine dependence. A comparison cohort of healthy participants (n=19) performed the BART under similar conditions. Modafinil treatment was associated with significantly higher BART scores (p=0.01), which were comparable to scores in healthy persons. BART scores in placebo treated participants were much lower than previously reported in healthy participants, and lower than those observed in the comparison cohort. As propensity toward risk taking is typically associated with higher BART scores as well as increased risk for substance use, our findings may reflect a novel aspect of cognitive impairment related to chronic cocaine use. Notably, the low BART scores reflect highly suboptimal performance on the task, and the observed effect of modafinil may indicate a normalization of this impairment and have implications for treatment outcome. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Preliminary Evidence for the Off-Label Treatment of Bulimia Nervosa With Psychostimulants: Six Case Reports.

    Science.gov (United States)

    Keshen, Aaron; Helson, Thomas

    2017-07-01

    Psychostimulants have been assessed in bulimia nervosa patients with comorbid attention deficit/hyperactivity disorder (ADHD), but few studies have examined the impact of psychostimulants on bulimia nervosa patients without comorbid ADHD. The aim of this study was to examine psychostimulants as a potential treatment for bulimia nervosa and to assess the concern of weight loss, given the medication's appetite-suppressing effects. This retrospective study describes 6 case reports of outpatients who were prescribed a psychostimulant specifically for their bulimia nervosa. The number of binge/purge days per months and body mass index were assessed. All patients demonstrated reductions in the number of binge/purge days per month, and 1 patient experienced total remission of bulimic symptoms. Minor fluctuations in weight were observed, but no clinically significant reductions in weight were noted. These findings support the need for clinical trials to examine the efficacy and safety of this potential treatment. © 2017, The American College of Clinical Pharmacology.

  15. Preliminary evidence that ketamine inhibits spreading depolarizations in acute human brain injury

    DEFF Research Database (Denmark)

    Sakowitz, Oliver W; Kiening, Karl L; Krajewski, Kara L

    2009-01-01

    , they cause or augment damage in the ischemic brain. A fraction of spreading depolarizations is abolished by N-methyl-d-aspartate receptor antagonists. Summary of Case- In 2 patients with severe acute brain injury (traumatic and spontaneous intracranial hemorrhage), spreading depolarizations were inhibited...... by the noncompetitive N-methyl-d-aspartate receptor antagonist ketamine. This restored electrocorticographic activity. CONCLUSIONS: These anecdotal electrocorticographic findings suggest that ketamine has an inhibitory effect on spreading depolarizations in humans. This is of potential interest for future...

  16. MMPI-2: Cluster Analysis of Personality Profiles in Perinatal Depression—Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Valentina Meuti

    2014-01-01

    Full Text Available Background. To assess personality characteristics of women who develop perinatal depression. Methods. The study started with a screening of a sample of 453 women in their third trimester of pregnancy, to which was administered a survey data form, the Edinburgh Postnatal Depression Scale (EPDS and the Minnesota Multiphasic Personality Inventory 2 (MMPI-2. A clinical group of subjects with perinatal depression (PND, 55 subjects was selected; clinical and validity scales of MMPI-2 were used as predictors in hierarchical cluster analysis carried out. Results. The analysis identified three clusters of personality profile: two “clinical” clusters (1 and 3 and an “apparently common” one (cluster 2. The first cluster (39.5% collects structures of personality with prevalent obsessive or dependent functioning tending to develop a “psychasthenic” depression; the third cluster (13.95% includes women with prevalent borderline functioning tending to develop “dysphoric” depression; the second cluster (46.5% shows a normal profile with a “defensive” attitude, probably due to the presence of defense mechanisms or to the fear of stigma. Conclusion. Characteristics of personality have a key role in clinical manifestations of perinatal depression; it is important to detect them to identify mothers at risk and to plan targeted therapeutic interventions.

  17. Evidence of slope failure in the Sines Contourite Drift area (SW Portuguese Continental Margin) - preliminary results

    Science.gov (United States)

    Teixeira, Manuel; Roque, Cristina; Terrinha, Pedro; Rodrigues, Sara; Ercilla, Gemma; Casas, David

    2017-04-01

    Slope instability, expressed by landslide activity, is an important natural hazard both onshore as well as offshore. Offshore processes create great concern on coastal areas constituting one of the major and most prominent hazards, directly by the damages they generate and indirectly by the possibility of generating tsunamis, which may affect the coast line. The Southwest Portuguese Continental Margin has been identified as an area where several mass movements occurred from Late Pleistocene to Present. Recently, an area of 52 km long by 34 km wide, affected by slope failure has been recognized in the Sines contourite drift located off the Alentejo. SWIM and CONDRIBER multibeam swath bathymetry has been used for the geomorphologic analysis and for recognition of mass movement scars on the seabed. Scars' areas and volumes were calculated by reconstructing paleo-bathymetry. The net gain and net loss were calculated using both paleo and present day bathymetry. Geomorphologically, the study area presents 4 morphologic domains with landslide scars: I) Shelf and upper slope display an irregular boundary with domain II with a sharp step ( 150m - 600m); II) Smooth area with gentle slope angles making the transition from smoother area to the continental slope (scarp), with large scars, suggesting slow rate and distributed mass wasting processes over this area ( 600 - 1200m); III) Scarp with high rates of retrograding instability, where faster processes are verified and a great number of gullies is feeding downslope area (1200m - 3200m); IV) Lebre Basin where mass movements deposits accumulate (> 3200m). A total of 51 landslide scars were identified with a total affected area of 137.67 km2, with 80.9 km2 being located in the continental slope with about 59% of the disrupted area, between 1200 and 3200m, and 41% (56.6 km2) lies in the continental shelf and upper slope, on a range of depths between 150 and 800m. The mean scar area is 2.7 km2 and the maximum area recorded on a scar is 7.63 km2, while the minimum is 0.14 km2. About 43% of the scars present areas below 2 km2 and 63% below 3 km2. Only 3.9% of the scars present areas higher than 7 km2. There is a total volume of displaced material of 4.46 km3 with a mean volume of 0.1 km3. The maximum volume recorded on a scar is 0.45 km3, while the minimum is 0.01 km3. The volume of material removed is quite variable, although the major part of the scars corresponds to a very small volume of removed material, with 69% of the scars presenting less than 0.1 km3. About 55% of the scars are located in slopes <=7° and 20% in slopes between 0 and 2°, while 24% of the scars belong to the class of slope gradient between 1.5 and 3°. We may conclude that there is, apparently, a reverse relationship between slope angle and scar area, meaning that slope is not the main condition for big landslide scars and that the areas with steep slopes, such as fault escarpments, favour continuous fast retrograde erosion. Publication supported by FCT- project UID/GEO/50019/2013 - Instituto Dom Luiz

  18. Global vs. regional approaches to the internationalisation process of Nigerian banks: some preliminary evidences

    OpenAIRE

    Acholonu, Kelechi K.; Boojihawon, Dev; Hanuman-Oogarah, Vanisha

    2010-01-01

    Research investigating internationalisation process of service firms from developing countries is limited. This paper draws on extant work on internationalisation of the firm, services’ internationalisation and proposes conceptual framework that investigates the internationalisation process of three leading Nigerian banks namely; Zenith Bank Nigeria (ZBN)Plc, First Bank of Nigeria (FBN) Plc and Intercontinental Bank Plc. This work attempts to evaluate the internationalisation process of these...

  19. Functional Role of Internal and External Visual Imagery: Preliminary Evidences from Pilates

    Directory of Open Access Journals (Sweden)

    Simone Montuori

    2018-01-01

    Full Text Available The present study investigates whether a functional difference between the visualization of a sequence of movements in the perspective of the first- (internal VMI-I or third- (external VMI-E person exists, which might be relevant to promote learning. By using a mental chronometry experimental paradigm, we have compared the time or execution, imagination in the VMI-I perspective, and imagination in the VMI-E perspective of two kinds of Pilates exercises. The analysis was carried out in individuals with different levels of competence (expert, novice, and no-practice individuals. Our results showed that in the Expert group, in the VMI-I perspective, the imagination time was similar to the execution time, while in the VMI-E perspective, the imagination time was significantly lower than the execution time. An opposite pattern was found in the Novice group, in which the time of imagination was similar to that of execution only in the VMI-E perspective, while in the VMI-I perspective, the time of imagination was significantly lower than the time of execution. In the control group, the times of both modalities of imagination were significantly lower than the execution time for each exercise. The present data suggest that, while the VMI-I serves to train an already internalised gesture, the VMI-E perspective could be useful to learn, and then improve, the recently acquired sequence of movements. Moreover, visual imagery is not useful for individuals that lack a specific motor experience. The present data offer new insights in the application of mental training techniques, especially in field of sports. However, further investigations are needed to better understand the functional role of internal and external visual imagery.

  20. Body Guilt: Preliminary Evidence for a Further Subjective Experience of Self-Objectification

    Science.gov (United States)

    Calogero, Rachel M.; Pina, Afroditi

    2011-01-01

    Two studies investigated body guilt (i.e., feeling regret and remorse over how the body looks and a desire for reparative action to "fix" the body) within the framework of objectification theory among predominantly White British undergraduate women. In Study 1 (N = 225), participants completed self-report measures of interpersonal sexual…

  1. Preliminary Evidence for a Classroom Based Psychosocial Intervention for Disaster Exposed Children with Posttraumatic Stress Symptomatology

    DEFF Research Database (Denmark)

    Elklit, Ask; Rønholt, Stine; Karsberg, Sidsel

    2013-01-01

    Abstract Background In 2004, a firework factory in a residential area of a large Danish city exploded. The children at the local school were screened for symptoms of posttraumatic stress disorder (PTSD) 16 months and 3 years after the incident. A large proportion of the children still suffered from...... with posttraumatic stress would be associated with reductions in symptoms. The second aim was to evaluate the usefulness of the Darryl, a cartoon-based PTSD screening instrument. Methods One hundred and eight children participated in the treatment program, all of whom fulfilled at least two out of the three DSM...

  2. Brief self-efficacy scales for use in weight-loss trials: Preliminary evidence of validity.

    Science.gov (United States)

    Wilson, Kathryn E; Harden, Samantha M; Almeida, Fabio A; You, Wen; Hill, Jennie L; Goessl, Cody; Estabrooks, Paul A

    2016-10-01

    Self-efficacy is a commonly included cognitive variable in weight-loss trials, but there is little uniformity in its measurement. Weight-loss trials frequently focus on physical activity (PA) and eating behavior, as well as weight loss, but no survey is available that offers reliable measurement of self-efficacy as it relates to each of these targeted outcomes. The purpose of this study was to test the psychometric properties of brief, pragmatic self-efficacy scales specific to PA, healthful eating and weight-loss (4 items each). An adult sample (n = 1,790) from 28 worksites enrolled in a worksite weight-loss program completed the self-efficacy scales, as well as measures of PA, dietary fat intake, and weight, at baseline, 6-, and 12-months. Confirmatory factor analysis supported the hypothesized factor structure indicating, 3 latent self-efficacy factors, specific to PA, healthful eating, and weight-loss. Measurement equivalence/invariance between relevant demographic groups, and over time was also supported. Parallel growth processes in self-efficacy factors and outcomes (PA, fat intake, and weight) support the predictive validity of score interpretations. Overall, this initial series of psychometric analyses supports the interpretation that scores on these scales reflect self-efficacy for PA, healthful eating, and weight-loss. The use of this instrument in large-scale weight-loss trials is encouraged. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  3. Attitudes toward elective abortion: preliminary evidence of validity for the Personal Beliefs Scale.

    Science.gov (United States)

    Embree, R A

    1998-06-01

    On the Personal Beliefs Scale of Embree and Embree item ratings obtained from 100 Midwestern undergraduates were used to classify participants into neutral, other, or second-order psychosomaticism mind-body belief types. Responses to a hypothetical abnormal pregnancy were used to measure attitude toward abortion (prochoice vs antichoice), meaning of abortion (not murder vs murder), and empathy for the unborn(low, moderate, or high). Values of chi 2 were statistically significant for students classified by mind-body belief type versus attitude toward abortion, and the meaning of abortion, but not for empathy for the unborn.

  4. Preliminary Evidence for a Second -525-545 Ma old Event of ...

    African Journals Online (AJOL)

    (1995), the 630-700 Ma old event that produced the Eastern Granulites may record regional crustal thickening arising out of collision of India, Madagascar, parts of Easten Antarctica and the Kalahari craton (IMSLEK terranes) with the Congo craton and the Arabian Nubian Shield (ANS). The younger granulite event recorded ...

  5. Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence

    OpenAIRE

    Weinstein, Maya; Myers, Vicki; Green, Dido; Schertz, Mitchell; Shiran, Shelly I.; Geva, Ronny; Artzi, Moran; Gordon, Andrew M.; Fattal-Valevski, Aviva; Ben Bashat, Dafna

    2015-01-01

    Neuroplasticity studies examining children with hemiparesis (CH) have focused predominantly on unilateral interventions. CH also have bimanual coordination impairments with bimanual interventions showing benefits. We explored neuroplasticity following hand-arm bimanual intensive therapy (HABIT) of 60 hours in twelve CH (6 females, mean age 11 ± 3.6 y). Serial behavioral evaluations and MR imaging including diffusion tensor (DTI) and functional (fMRI) imaging were performed before, immediately...

  6. Exchange rates and individual good's price misalignment: Some preliminary evidence of long-horizon predictability

    OpenAIRE

    Dong, Wei; Nam, Deokwoo

    2011-01-01

    When prices are sticky, movements in the nominal exchange rate have a direct impact on international relative prices. A relative price misalignment would trigger an adjustment in consumption and employment, and may help to predict future movements in the exchange rate. Although purchasing-power-parity fundamentals, in general, have only weak predictability, currency misalignment may be indicated by price differentials for some goods, which could then have predictive power for subsequent re-ev...

  7. Preliminary Evidence That Growth in Productive Language Differentiates Childhood Stuttering Persistence and Recovery

    Science.gov (United States)

    Leech, Kathryn A.; Ratner, Nan Bernstein; Brown, Barbara; Weber, Christine M.

    2017-01-01

    Purpose: Childhood stuttering is common but is often outgrown. Children whose stuttering persists experience significant life impacts, calling for a better understanding of what factors may underlie eventual recovery. In previous research, language ability has been shown to differentiate children who stutter (CWS) from children who do not stutter,…

  8. DAT1-Genotype and Menstrual Cycle, but Not Hormonal Contraception, Modulate Reinforcement Learning: Preliminary Evidence.

    Science.gov (United States)

    Jakob, Kristina; Ehrentreich, Hanna; Holtfrerich, Sarah K C; Reimers, Luise; Diekhof, Esther K

    2018-01-01

    Hormone by genotype interactions have been widely ignored by cognitive neuroscience. Yet, the dependence of cognitive performance on both baseline dopamine (DA) and current 17ß-estradiol (E2) level argues for their combined effect also in the context of reinforcement learning. Here, we assessed how the interaction between the natural rise of E2 in the late follicular phase (FP) and the 40 base-pair variable number tandem repeat polymorphism of the dopamine transporter (DAT1) affects reinforcement learning capacity. 30 women with a regular menstrual cycle performed a probabilistic feedback learning task twice during the early and late FP. In addition, 39 women, who took hormonal contraceptives (HC) to suppress natural ovulation, were tested during the "pill break" and the intake phase of HC. The present data show that DAT1-genotype may interact with transient hormonal state, but only in women with a natural menstrual cycle. We found that carriers of the 9-repeat allele (9RP) experienced a significant decrease in the ability to avoid punishment from early to late FP. Neither homozygote subjects of the 10RP allele, nor subjects from the HC group showed a change in behavior between phases. These data are consistent with neurobiological studies that found that rising E2 may reverse DA transporter function and could enhance DA efflux, which would in turn reduce punishment sensitivity particularly in subjects with a higher transporter density to begin with. Taken together, the present results, although based on a small sample, add to the growing understanding of the complex interplay between different physiological modulators of dopaminergic transmission. They may not only point out the necessity to control for hormonal state in behavioral genetic research, but may offer new starting points for studies in clinical settings.

  9. DAT1-Genotype and Menstrual Cycle, but Not Hormonal Contraception, Modulate Reinforcement Learning: Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Kristina Jakob

    2018-02-01

    Full Text Available Hormone by genotype interactions have been widely ignored by cognitive neuroscience. Yet, the dependence of cognitive performance on both baseline dopamine (DA and current 17ß-estradiol (E2 level argues for their combined effect also in the context of reinforcement learning. Here, we assessed how the interaction between the natural rise of E2 in the late follicular phase (FP and the 40 base-pair variable number tandem repeat polymorphism of the dopamine transporter (DAT1 affects reinforcement learning capacity. 30 women with a regular menstrual cycle performed a probabilistic feedback learning task twice during the early and late FP. In addition, 39 women, who took hormonal contraceptives (HC to suppress natural ovulation, were tested during the “pill break” and the intake phase of HC. The present data show that DAT1-genotype may interact with transient hormonal state, but only in women with a natural menstrual cycle. We found that carriers of the 9-repeat allele (9RP experienced a significant decrease in the ability to avoid punishment from early to late FP. Neither homozygote subjects of the 10RP allele, nor subjects from the HC group showed a change in behavior between phases. These data are consistent with neurobiological studies that found that rising E2 may reverse DA transporter function and could enhance DA efflux, which would in turn reduce punishment sensitivity particularly in subjects with a higher transporter density to begin with. Taken together, the present results, although based on a small sample, add to the growing understanding of the complex interplay between different physiological modulators of dopaminergic transmission. They may not only point out the necessity to control for hormonal state in behavioral genetic research, but may offer new starting points for studies in clinical settings.

  10. Development of an Online and Offline Integration Hypothesis for Healthy Internet Use: Theory and Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Xiaoyan Lin

    2018-04-01

    Full Text Available The Internet has become an integral part of our daily life, and how to make the best use of the Internet is important to both individuals and the society. Based on previous studies, an Online and Offline Integration Hypothesis is proposed to suggest a framework for considering harmonious and balanced Internet use. The Integration Hypothesis proposes that healthier patterns of Internet usage may be achieved through harmonious integration of people’s online and offline worlds. An online/offline integration is proposed to unite self-identity, interpersonal relationships, and social functioning with both cognitive and behavioral aspects by following the principles of communication, transfer, consistency, and “offline-first” priorities. To begin to test the hypothesis regarding the relationship between integration level and psychological outcomes, data for the present study were collected from 626 undergraduate students (41.5% males. Participants completed scales for online and offline integration, Internet addiction, pros and cons of Internet use, loneliness, extraversion, and life satisfaction. The findings revealed that subjects with higher level of online/offline integration have higher life satisfaction, greater extraversion, and more positive perceptions of the Internet and less loneliness, lower Internet addiction, and fewer negative perceptions of the Internet. Integration mediates the link between extraversion and psychological outcomes, and it may be the mechanism underlying the difference between the “rich get richer” and social compensation hypotheses. The implications of the online and offline integration hypothesis are discussed.

  11. Preliminary evidence for a postsynaptic action of beta-bungarotoxin in mammalian skeletal muscle

    Science.gov (United States)

    Storella, R. J.; Schouchoff, A. L.; Fujii, M.; Hill, J.; Fletcher, J. E.; Jiang, M. S.; Smith, L. A.

    1992-01-01

    Two hours after treatment with beta-bungarotoxin (0.34-0.4 microM), when there was complete neuromuscular block, the peak contracture response to 50 microM succinylcholine was significantly reduced by about 35% in the mouse phrenic nerve-diaphragm preparation. Additionally, significant phospholipase A2 activity was detected on primary cell cultures from skeletal muscle which were incubated for 2 hr with concentrations of beta-bungarotoxin greater than or equal to 0.1 microM. Thus, beta-bungarotoxin appears to have pharmacologically and biochemically detectable postsynaptic actions in mammalian muscle systems.

  12. Preliminary Evidence for the Amplification of Global Warming in Shallow, Intertidal Estuarine Waters

    Science.gov (United States)

    Over the past 50 years, mean annual water temperature in northeastern U.S. estuaries has increased by approximately 1.2°C, with most of the warming recorded in the winter and early spring. We hypothesize that this warming may be amplified in the shallow (<2m), nearshore portions ...

  13. Characteristic of microplastics in the atmospheric fallout from Dongguan city, China: preliminary research and first evidence.

    Science.gov (United States)

    Cai, Liqi; Wang, Jundong; Peng, Jinping; Tan, Zhi; Zhan, Zhiwei; Tan, Xiangling; Chen, Qiuqiang

    2017-11-01

    Microplastic pollution has exhibited a global distribution, including seas, lakes, rivers, and terrestrial environment in recent years. However, little attention was paid on the atmospheric environment, though the fact that plastic debris can escape as wind-blown debris was previously reported. Thus, characteristics of microplastics in the atmospheric fallout from Dongguan city were preliminarily studied. Microplastics of three different polymers, i.e., PE, PP, and PS, were identified. Diverse shapes of microplastics including fiber, foam, fragment, and film were found, and fiber was the dominant shape of the microplastics. SEM images illustrated that adhering particles, grooves, pits, fractures, and flakes were the common patterns of degradation. The concentrations of non-fibrous microplastics and fibers ranged from 175 to 313 particles/m 2 /day in the atmospheric fallout. Thus, dust emission and deposition between atmosphere, land surface, and aquatic environment were associated with the transportation of microplastics.

  14. Comparing intensities and modalities within the sensory attenuation paradigm: Preliminary evidence

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    Dalila Burin

    2017-11-01

    Full Text Available It is well-documented that the intensity of a self-generated somatosensory stimulus is perceived to be attenuated in respect to an identical stimulus generated by others. At present, it is not clear whether such a phenomenon, known as somatosensory attenuation, is based not only on feedforward motor signals but also on re-afferences towards the body. To answer this question, in the present pilot investigation on twelve healthy subjects, three types of stimulations (sensory non-nociceptive electrical – ES, nociceptive electrical – NES, and vibrotactile – VTS and intensities (1 = sensory threshold ∗ 2.5 + 2 mA, 2 = sensory threshold ∗ 2.5 + 3 mA, 3 = sensory threshold ∗ 2.5 + 4 mA for ES and NES; 1 = sensory threshold ∗ 2 Hz, 2 = sensory threshold ∗ 3 Hz, 3 = sensory threshold ∗ 4 Hz for VTS have been directly compared in a somatosensory attenuation paradigm. The results show that the attenuation effect emerged only with electrical stimuli and that it increased with higher intensities. These pilot findings suggest that, depending on the type and the intensity of stimulation, re-afferences can have a role in somatosensory attenuation. Additionally, it is possible to speculate the effect is present only with electrical stimuli because those stimuli are prospectively judged as potentially dangerous. This, in turn, would optimize planning successful reactions to incoming threatening stimuli.

  15. Assessing Critical Thinking in Higher Education: The HEIghten™ Approach and Preliminary Validity Evidence

    Science.gov (United States)

    Liu, Ou Lydia; Mao, Liyang; Frankel, Lois; Xu, Jun

    2016-01-01

    Critical thinking is a learning outcome highly valued by higher education institutions and the workforce. The Educational Testing Service (ETS) has designed a next generation assessment, the HEIghten™ critical thinking assessment, to measure students' critical thinking skills in analytical and synthetic dimensions. This paper introduces the…

  16. Preliminary Evidence that Self-Efficacy Predicts Physical Activity in Multiple Sclerosis

    Science.gov (United States)

    Motl, Robert W.; McAuley, Edward; Doerksen, Shawna; Hu, Liang; Morris, Katherine S.

    2009-01-01

    Individuals with multiple sclerosis (MS) are less physically active than nondiseased people. One method for increasing physical activity levels involves the identification of factors that correlate with physical activity and that are modifiable by a well designed intervention. This study examined two types of self-efficacy as cross-sectional and…

  17. Preliminary evidence of salivary cortisol predicting performance in a controlled setting.

    Science.gov (United States)

    Lautenbach, Franziska; Laborde, Sylvain; Achtzehn, Silvia; Raab, Markus

    2014-04-01

    The aims of this study were to examine the influence of salivary cortisol on tennis serve performance in a controlled setting and to investigate if cortisol predicts unique variance in performance beyond a subjective anxiety measure (i.e., Competitive State Anxiety Inventory-2 [CSAI-2]). Twenty-three tennis players performed two series of second tennis serves separated by an anxiety induction (i.e., arithmetic task). Cortisol was assessed six times during the experiment. Results show that cortisol response and a drop in serving performance are positively correlated (r=.68, pperformance (i.e., 19%) beyond CSAI-2 measures. Thus, considering cortisol measurements seems warranted in future research aimed at understanding performance. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Dual-Language Education for Low-Income Children: Preliminary Evidence of Benefits for Executive Function

    Science.gov (United States)

    Esposito, Alena G.; Baker-Ward, Lynne

    2013-01-01

    This investigation is an initial examination of possible enhancement of executive function through a dual-language (50:50) education model. The ethnically diverse, low-income sample of 120 children from Grades K, 2, and 4 consisted of approximately equal numbers of children enrolled in dual-language and traditional classrooms. Dual-language…

  19. Neurophysiological correlates of eye movement desensitization and reprocessing sessions: preliminary evidence for traumatic memories integration.

    Science.gov (United States)

    Farina, Benedetto; Imperatori, Claudio; Quintiliani, Maria I; Castelli Gattinara, Paola; Onofri, Antonio; Lepore, Marta; Brunetti, Riccardo; Losurdo, Anna; Testani, Elisa; Della Marca, Giacomo

    2015-11-01

    We have investigated the potential role of eye movement desensitization and reprocessing (EMDR) in enhancing the integration of traumatic memories by measuring EEG coherence, power spectra and autonomic variables before (pre-EMDR) and after (post-EMDR) EMDR sessions during the recall of patient's traumatic memory. Thirteen EMDR sessions of six patients with post-traumatic stress disorder were recorded. EEG analyses were conducted by means of the standardized Low Resolution Electric Tomography (sLORETA) software. Power spectra, EEG coherence and heart rate variability (HRV) were compared between pre- and post-EMDR sessions. After EMDR, we observed a significant increase of alpha power in the left inferior temporal gyrus (T = 3.879; P = 0.041) and an increased EEG coherence in beta band between C3 and T5 electrodes (T = 6.358; P EMDR sessions was also observed (pre-EMDR: 6.38 ± 6.83; post-EMDR: 2.46 ± 2.95; U-Test = 45, P = 0.043). Finally, the values of lagged coherence were negatively associated with subjective units of disturbance (r(24) = -0.44, P EMDR leads to an integration of dissociated aspects of traumatic memories and, consequently, a decrease of hyperarousal symptoms [Correction made here after initial publication]. © 2014 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  20. Preliminary Evidence for an Automatic Link between Sex and Power among Men Who Molest Children

    Science.gov (United States)

    Kamphuis, Jan H.; De Ruiter, Corine; Janssen, Bas; Spiering, Mark

    2005-01-01

    Understanding critical motivational processes of sexual offenders may ultimately provide important clues to more effective treatments. Implicit, automatic cognitive processes have received minimal attention; however, a lexical decision experiment revealed automatic links between the concepts of power and sex among participants who self-reported…

  1. Pickles and Ice Cream! Food Cravings in Pregnancy: Hypotheses, Preliminary Evidence, and Directions for Future Research

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    Natalia C. Orloff

    2014-09-01

    Full Text Available Women in the United States experience an increase in food cravings at two specific times during their life, 1 perimenstrually and 2 prenatally. The prevalence of excess gestational weight gain (GWG is a growing concern due to its association with adverse health outcomes in both mothers and children. To the extent that prenatal food cravings may be a determinant of energy intake in pregnancy, a better understanding of craving etiology could be crucial in addressing the issue of excessive GWG. This paper reviews the available literature to corroborate and/or dispute some of the most commonly accepted hypotheses regarding the causes of food cravings during pregnancy, including a role of 1 hormonal changes, 2 nutritional deficits, 3 pharmacologically active ingredients in the desired foods, and 4 cultural and psychosocial factors. An existing model of perimenstrual chocolate craving etiology serves to structure the discussion of these hypotheses. The main hypotheses discussed receive little support, with the notable exception of a postulated role of cultural and psychosocial factors. The presence of cravings during pregnancy is a common phenomenon across different cultures, but the types of foods desired and the adverse impact of cravings on health may be culture-specific. Various psychosocial factors appear to correlate with excess GWG, including the presence of restrained eating. Findings strongly suggest that more research be conducted in this area. We propose that future investigations fall into one of the four following categories: 1 validation of food craving and eating-related measures specifically in pregnant populations, 2 use of ecological momentary assessment to obtain real time data on cravings during pregnancy, 3 implementation of longitudinal studies to address causality between eating disorder symptoms, food cravings, and gestational weight gain, and 4 development of interventions to ensure proper prenatal nutrition and prevent excess GWG.

  2. Associations between Dopamine and Serotonin Genes and Job Satisfaction: Preliminary Evidence from the Add Health Study

    Science.gov (United States)

    Song, Zhaoli; Li, Wendong; Arvey, Richard D.

    2011-01-01

    Previous behavioral genetic studies have found that job satisfaction is partially heritable. We went a step further to examine particular genetic markers that may be associated with job satisfaction. Using an oversample from the National Adolescent Longitudinal Study (Add Health Study), we found 2 genetic markers, dopamine receptor gene DRD4 VNTR…

  3. The Role of Political Information in Union Certification Elections: Preliminary Evidence from Selected States

    Directory of Open Access Journals (Sweden)

    Michael Toma

    2005-12-01

    Full Text Available This paper focuses a public choice lens on the rationality of voters in U.S. union certification elections in fourteen selected states between 1994 and 2001. These elections are characterized by conditions that are favorable for empirical tests of the rational voter model. The electorates are relatively small, the potential benefits can be significant, and the costs of voting are negligible. The empirical work yields three straightforward results. First, voter participation is negatively related to the size of the electorate. Second, the margin of victory is negatively related to the voter participation rate. Third, as the political climate becomes more liberal, the voter participation rate declines. This suggests that in labor-friendly states, there is less of an incentive to vote either for or against certifying a union to collective bargain on behalf of workers.

  4. Articulatory Changes Following Treatment of Muscle Tension Dysphonia: Preliminary Acoustic Evidence

    Science.gov (United States)

    Dromey, Christopher; Nissen, Shawn L.; Roy, Nelson; Merrill, Ray M.

    2008-01-01

    Purpose: Primary muscle tension dysphonia (MTD), a voice disturbance that occurs in the absence of structural or neurological pathology, may respond to manual circumlaryngeal techniques, which ostensibly alter the posture of the larynx and/or the configuration of the vocal folds without directly targeting supralaryngeal articulatory structures.…

  5. Preliminary Evidence of Preattentive Distinctions of Frequency-Modulated (FM tones that Convey Affect

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    David I Leitman

    2011-10-01

    Full Text Available Recognizing emotion is an evolutionary imperative. An early stage of auditory scene analysis involves the perceptual grouping of acoustic features, which can be based on both temporal coincidence and spectral features such as perceived pitch. Perceived pitch, or fundamental frequency (F0, is an especially salient cue for differentiating affective intent through speech intonation (prosody. We hypothesized that: 1 simple frequency modulated (FM tone abstractions, based on the parameters of actual prosodic stimuli, would be reliably classified as representing differing emotional categories; and 2 that such differences would yield significant mismatch negativities (MMNs - an index of preattentive deviance detection within the auditory environment. We constructed a set of FM tones that approximated the F0 mean and variation of reliably-recognized happy and neutral prosodic stimuli. These stimuli were presented to 13 subjects using a passive listening oddball paradigm. We additionally included stimuli with no frequency modulation (FM and FM tones with identical carrier frequencies but differing modulation depths as control conditions. Following electrophysiological recording, subjects were asked to identify the sounds they heard as happy, sad, angry or neutral. We observed that FM tones abstracted from happy and no expression speech stimuli elicited MMNs. Post-hoc behavioral testing revealed that subjects reliably identified the FM tones in a consistent manner. Finally, we also observed that FM tones and no-FM tones elicited equivalent MMNs. MMNs to FM tones that differentiate affect suggests that these abstractions may be sufficient to characterize prosodic distinctions, and that these distinctions can be represented in pre-attentive auditory sensory memory.

  6. Binge eating disorder and obesity: preliminary evidence for distinct cardiovascular and psychological phenotypes.

    Science.gov (United States)

    Klatzkin, Rebecca R; Gaffney, Sierra; Cyrus, Kathryn; Bigus, Elizabeth; Brownley, Kimberly A

    2015-04-01

    This study investigated cardiovascular functioning, mood, and eating-related psychological factors at rest and in response to mental stress in three groups of women: 1) Obese women with binge eating disorder (BED; n=9); 2) obese non-BED women (n=15); and 3) normal weight (NW) non-BED women (n=15). Compared to both obese and NW non-BED women, obese women with BED showed heightened overall blood pressure and reported greater depression symptoms, perceived stress, and eating-related psychopathology. Additionally, obese women with BED reported greater overall negative affect and state anxiety compared to obese non-BED women. The heart rate response to stress was blunted in the obese BED group compared to the other groups, but this effect was no longer significant after controlling for baseline differences in depression. Correlational analyses revealed a positive association between stress-induced changes in hunger and cardiovascular measures only in obese women with BED. Longitudinal studies are needed to determine if stress dysregulation and stress-induced increases in hunger contribute to the onset and/or maintenance of BED. In particular, studies utilizing an additional NW BED control group are warranted in order to further examine the impact of BED above and beyond the impact of obesity on psychophysiological functioning and to inform the growing literature regarding stress-related factors that distinguish the BED and obesity phenotypes. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Preliminary evidences of circadian fan activity rhythm in Sabella spallanzanii (Gmelin, 1791 (Polychaeta: Sabellidae

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    Jacopo Aguzzi

    2006-12-01

    Full Text Available The fan activity rhythm of Sabella spallanzanii (Gmelin, 1791 and its entrainment capability to light were studied. Animals were tested under constant darkness (DD followed by two consecutive 24 h light-darkness regimes: a first 11 h light period (LD and a second 9 h light period, with its phase inverted (DL. An infrared analogical video-camera took shots each 30 s. A number of pictures with open fan were counted every 15 min. In DD a weak free-running periodicity in the circadian range was found, thus reinforcing the matching of the 24 h period under study in both photoperiod regimes. A nocturnal activity was characterised with a consistent anticipation to lightOFF (i.e. entrainment. Moreover, this phase of entrainment differed between DL and LD. The presence of endogenous activity rhythm with a variable phase angle of entrainment is a distinctive feature of circadian pacemakers.

  8. Preliminary evidence for performance enhancement following parietal lobe stimulation in Developmental Dyscalculia

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    Teresa eIuculano

    2014-02-01

    Full Text Available Nearly 7% of the population exhibit difficulties in dealing with numbers and performing arithmetic, a condition named Developmental Dyscalculia (DD, which significantly affects the educational and professional outcomes of these individuals, as it often persists into adulthood. Research has mainly focused on behavioral rehabilitation, while little is known about performance changes and neuroplasticity induced by the concurrent application of brain-behavioral approaches. It has been shown that numerical proficiency can be enhanced by applying a small – yet constant – current through the brain, a non-invasive technique named transcranial electrical stimulation (tES. Here we combined a numerical learning paradigm with transcranial direct current stimulation (tDCS in two adults with DD to assess the potential benefits of this methodology to remediate their numerical difficulties. Subjects learned to associate artificial symbols to numerical quantities within the context of a trial and error paradigm, while tDCS was applied to the posterior parietal cortex (PPC. The first subject (DD1 received anodal stimulation to the right PPC and cathodal stimulation to the left PPC, which has been associated with numerical performance’s improvements in healthy subjects. The second subject (DD2 received anodal stimulation to the left PPC and cathodal stimulation to the right PPC, which has been shown to impair numerical performance in healthy subjects. We examined two indices of numerical proficiency: (i automaticity of number processing; and (ii mapping of numbers onto space. Our results are opposite to previous findings with non-dyscalculic subjects. Only anodal stimulation to the left PPC improved both indices of numerical proficiency. These initial results represent an important step to inform the rehabilitation of developmental learning disabilities, and have relevant applications for basic and applied research in cognitive neuroscience, rehabilitation, and education.

  9. Preliminary Compositional Evidence of Provenance of Ceramics from Hatahara Archaeological Site, Central Amazonia

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    K. P. Nunes

    2013-01-01

    Full Text Available One hundred twenty four ceramic fragments and six clay samples from the Hatahara archaeological site in Amazonas state, Brazil, were analyzed using instrumental neutron activation analysis, INAA, to determine the concentration of twenty chemical elements: Ce, Co, Cr, Cs, Eu, Fe, Hf, K, La, Lu, Na, Nd, Rb, Sc, Ta, Tb, Th, U, Yb, and Zn. The dataset was submitted to multivariate statistical analysis. The classification was done by cluster analysis and discriminant analysis. The results demonstrated the occurrence of four different groups of ceramics, which represent three archaeological phases: Paredão, Manacapuru, and Guarita. This data is consistent with previous traditional petrographic examination of the ceramic samples. Based on probability measures, the great majority of the ceramics are considered to be local in origin.

  10. Preliminary Evidence for Training-Induced Changes of Morphology and Phantom Limb Pain

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    Sandra Preißler

    2017-06-01

    Full Text Available The aim of this study was to investigate whether a special prosthetic training in phantom limb pain patients aimed at increasing the functional use of the prosthesis leads to neural morphological plasticity of brain structures and a reduction in phantom limb pain. For chronic pain disorders, it was shown that morphological alterations due to pain might become at least partially reversed by pain therapies. Phantom limb pain is a chronic pain disorder that is frequently followed by neural plasticity of anatomical brain structures. In our study, 10 patients with amputation of the upper limb participated in a two-week training with a myoelectric prosthesis with somatosensory feedback. Grip strength was fed back with electrocutaneous stimulus patterns applied to the stump. Phantom limb pain was assessed before and after the two-week training. Similarly, two T1 weighted MRI scans were conducted for longitudinal thickness analyses of cortical brain structures. As result of this treatment, patients experienced a reduction in phantom limb pain and a gain in prosthesis functionality. Furthermore, we found a change of cortical thickness in small brain areas in the visual stream and the post-central gyrus ipsilateral to the amputation indicating morphological alterations in brain areas involved in vision and pain processing.

  11. Preliminary evidence that both blue and red light can induce alertness at night

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    Plitnick Barbara

    2009-08-01

    Full Text Available Abstract Background A variety of studies have demonstrated that retinal light exposure can increase alertness at night. It is now well accepted that the circadian system is maximally sensitive to short-wavelength (blue light and is quite insensitive to long-wavelength (red light. Retinal exposures to blue light at night have been recently shown to impact alertness, implicating participation by the circadian system. The present experiment was conducted to look at the impact of both blue and red light at two different levels on nocturnal alertness. Visually effective but moderate levels of red light are ineffective for stimulating the circadian system. If it were shown that a moderate level of red light impacts alertness, it would have had to occur via a pathway other than through the circadian system. Methods Fourteen subjects participated in a within-subject two-night study, where each participant was exposed to four experimental lighting conditions. Each night each subject was presented a high (40 lx at the cornea and a low (10 lx at the cornea diffuse light exposure condition of the same spectrum (blue, λmax = 470 nm, or red, λmax = 630 nm. The presentation order of the light levels was counterbalanced across sessions for a given subject; light spectra were counterbalanced across subjects within sessions. Prior to each lighting condition, subjects remained in the dark ( Results Exposures to red and to blue light resulted in increased beta and reduced alpha power relative to preceding dark conditions. Exposures to high, but not low, levels of red and of blue light significantly increased heart rate relative to the dark condition. Performance and sleepiness ratings were not strongly affected by the lighting conditions. Only the higher level of blue light resulted in a reduction in melatonin levels relative to the other lighting conditions. Conclusion These results support previous findings that alertness may be mediated by the circadian system, but it does not seem to be the only light-sensitive pathway that can affect alertness at night.

  12. The Antipsychotics and Sexual Functioning Questionnaire (ASFQ) : Preliminary evidence for reliability and validity

    NARCIS (Netherlands)

    de Boer, M.K.; Castelein, Stynke; Bous, Johan; van den Heuvel, Edwin R.; Wiersma, Durk; Schoevers, Robert A.; Knegtering, Henderikus

    2013-01-01

    The aim of this study is to describe the psychometric properties of the Antipsychotics and Sexual Functioning Questionnaire (ASFQ). Internal reliability, test-retest reliability, inter-rater reliability, validity and sensitivity to change were calculated in a sample of 30 patients with schizophrenia

  13. Preliminary Evidence for the Impact of Combat Experiences on Gray Matter Volume of the Posterior Insula

    OpenAIRE

    Clausen, Ashley N.; Billinger, Sandra A.; Sisante, Jason-Flor V.; Suzuki, Hideo; Aupperle, Robin L.

    2017-01-01

    Background: Combat-exposed veteran populations are at an increased risk for developing cardiovascular disease. The anterior cingulate cortex (ACC) and insula have been implicated in both autonomic arousal to emotional stressors and homeostatic processes, which may contribute to cardiovascular dysfunction in combat veteran populations. The aim of the present study was to explore the intersecting relationships of combat experiences, rostral ACC and posterior insula volume, and cardiovascular he...

  14. Auditory rehabilitation for interaural asymmetry: preliminary evidence of improved dichotic listening performance following intensive training.

    Science.gov (United States)

    Moncrieff, Deborah W; Wertz, Diane

    2008-02-01

    Children with dichotic left ear deficits received intensive training in phase I and phase II clinical trials designed to establish the efficacy of directly training dichotic listening. Dichotic verbal material was presented in the sound field with intensity adjusted separately for each speaker. Output from the right-sided speaker was initially 20-30 db HL lower than for the left-sided speaker, resulting in excellent performance in the left ear. Intensities were adaptively adjusted throughout training in 1, 2, and 5-dB steps in order to keep performance high across dichotic tasks. In both phase I (n=8) and phase II (n=13) trials, children demonstrated significant gains in dichotic left ear performance after training. In phase II, children also demonstrated significant gains in right ear performance. Overall results from the two trials support the feasibility of this training approach for improving a larger than normal interaural asymmetry on dichotic listening tasks. Significant improvements in language comprehension and word recognition in phase II suggest that this type of training may also facilitate language skills in some children.

  15. Evidence for alpha-MSH binding sites on human scalp hair follicles: preliminary results

    NARCIS (Netherlands)

    Nanninga, P. B.; Ghanem, G. E.; Lejeune, F. J.; Bos, J. D.; Westerhof, W.

    1991-01-01

    Alpha-MSH, considered an important pigmentation hormone, binds to melanocytes and is thought to stimulate melanogenesis through a cyclic-AMP-dependent mechanism. The binding of alpha-MSH to follicular melanocytes has been investigated in human hair of different colors, ranging from black to blond

  16. Evidence suggests rigid aortic grafts increase systolic blood pressure: results of a preliminary study.

    Science.gov (United States)

    O'Brien, T; Morris, L; McGloughlin, T

    2008-01-01

    Abdominal aortic aneurysm (AAA) is a serious complication of the aorta and is treated using vascular bypass grafts. Two main classes of graft are available to treat AAA; grafts implanted by open surgery and stent-grafts implanted using minimally invasive endovascular techniques. Both classes of graft consist of an aortic section which bifurcates into two iliac sections. It has been hypothesized that implantation of aortic grafts and stent-grafts serve to significantly increase abdominal aortic pressures. In this study, an open-loop computer-controlled pumping system was built to produce physiologically realistic pressure and flow-rates. Models of a compliant abdominal aortic aneurysm, a compliant walled graft and a tapered graft were manufactured using an injection moulding technique and fused deposition modelling was used to create a rigid walled graft. A specific transient flow-rate waveform was then applied at the inlet of each model and the resulting pressure waveforms 30 mm upstream from the bifurcation was recorded. Peak pressure measurements were recorded over the course of the pulse for each model. The compliant aneurysm model was found to have a systolic pressure of 107 mmHg while the complaint graft model was 153 mmHg. The rigid graft model had a peak systolic pressure of 199 mmHg. In the tapered graft, the peak pressure dropped to 142 mmHg. The data suggests that implanting a graft model in place of an aneurysm model in an in vitro flow circuit can increase the pressures recorded upstream from the iliac bifurcation and that tapered grafts may alleviate this problem.

  17. Association between virtues and posttraumatic growth: preliminary evidence from a Chinese community sample after earthquakes

    Directory of Open Access Journals (Sweden)

    Wenjie Duan

    2015-04-01

    Full Text Available Objective. Relationship, vitality, and conscientiousness are three fundamental virtues that have been recently identified as important individual differences to health, well being, and positive development. This cross-sectional study attempted to explore the relationship between the three constructs and post-traumatic growth (PTG in three directions, including indirect trauma samples without post-traumatic stress disorder (PTSD, direct trauma samples without PTSD, and direct trauma samples with PTSD.Methods. A total of 340 community participants from Sichuan Province, Mainland China involved in the study, most of which experienced Wenchuan and Lushan Earthquake. Participants were required to complete the self-reported questionnaire packages at one time point for obtaining their scores on virtues (Chinese Virtues Questionnaire, PTSD (PTSD Checklist-Specific, and PTG (Post-traumatic Growth Inventory-Chinese.Results. Significant and positive correlations between the three virtues and PTG were identified (r = .39–.56; p < .01. Further regression analysis by stepwise method reveled that: in the indirect trauma samples, vitality explained 32% variance of PTG. In reference to the direct trauma sample without PTSD, both relationship and conscientiousness explained 32% variance of PTG, whereas in the direct trauma sample with PTSD, only conscientiousness accounted for 31% the variance in PTG.Conclusion.This cross-sectional investigation partly revealed the roles of different virtues in trauma context. Findings suggest important implications for strengths-based treatment.

  18. Development of an Online and Offline Integration Hypothesis for Healthy Internet Use: Theory and Preliminary Evidence.

    Science.gov (United States)

    Lin, Xiaoyan; Su, Wenliang; Potenza, Marc N

    2018-01-01

    The Internet has become an integral part of our daily life, and how to make the best use of the Internet is important to both individuals and the society. Based on previous studies, an Online and Offline Integration Hypothesis is proposed to suggest a framework for considering harmonious and balanced Internet use. The Integration Hypothesis proposes that healthier patterns of Internet usage may be achieved through harmonious integration of people's online and offline worlds. An online/offline integration is proposed to unite self-identity, interpersonal relationships, and social functioning with both cognitive and behavioral aspects by following the principles of communication, transfer, consistency, and "offline-first" priorities. To begin to test the hypothesis regarding the relationship between integration level and psychological outcomes, data for the present study were collected from 626 undergraduate students (41.5% males). Participants completed scales for online and offline integration, Internet addiction, pros and cons of Internet use, loneliness, extraversion, and life satisfaction. The findings revealed that subjects with higher level of online/offline integration have higher life satisfaction, greater extraversion, and more positive perceptions of the Internet and less loneliness, lower Internet addiction, and fewer negative perceptions of the Internet. Integration mediates the link between extraversion and psychological outcomes, and it may be the mechanism underlying the difference between the "rich get richer" and social compensation hypotheses. The implications of the online and offline integration hypothesis are discussed.

  19. The Self-Presentation Motives for Physical Activity Questionnaire: Instrument Development and Preliminary Construct Validity Evidence.

    Science.gov (United States)

    Howle, Timothy C; Dimmock, James A; Whipp, Peter R; Jackson, Ben

    2015-06-01

    With the aim of advancing the literature on impression management in physical activity settings, we developed a theoretically derived 2 by 2 instrument that was designed to measure different types of context-specific self-presentation motives. Following item generation and expert review (Study 1), the instrument was completed by 206 group exercise class attendees (Study 2) and 463 high school physical education students (Study 3). Our analyses supported the intended factor structure (i.e., reflecting acquisitive-agentic, acquisitive-communal, protective-agentic, and protective-communal motives). We found some support for construct validity, and the self-presentation motives were associated with variables of theoretical and applied interest (e.g., impression motivation and construction, social anxiety, social and achievement goals, efficacy beliefs, engagement). Taken together, the results indicate that the Self-presentation Motives for Physical Activity Questionnaire (SMPAQ) may be useful for measuring various types of self-presentation motives in physical activity settings.

  20. Preliminary evidence that schizophrenia liability at age 15 predicts suicidal ideation two years later.

    Science.gov (United States)

    Schimanski, Irie D; Mouat, Kelly L; Billinghurst, Bronwyn L; Linscott, Richard J

    2017-03-01

    We tested artifactual and theory-based accounts of the relationship between schizophrenia liability and suicidality. At baseline, 387 adolescents (12 to 17years) completed measures of schizotypy, hopelessness, and depressed affect. After two years, schizotypal and non-schizotypal subsamples (n=16 and 31, respectively) self-reported passive suicidal ideation, active ideation, and serious ideation and action. Taxonic schizotypy predicted passive ideation (OR=8.15, 95% CI 1.34, 49.60) even when controlling for depressed affect. Hopelessness did not predict suicidality or moderate schizotypy-suicidality relationships. Findings were consistent with the interpersonal theory of suicide and contrary to the artifactual account of the association. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Precambrian mega lineaments across the Indian sub-continent - Preliminary evidence from offshore magnetic data

    Digital Repository Service at National Institute of Oceanography (India)

    Subrahmanyam, V.; Subrahmanyam, A; Murthy, K.S.R.; Murty, G.P.S.; Sarma, K.V.L.N.S.; SuneetaRani, P.; Anuradha, A

    continental block between 10°45`N and 12°30`N exhibit distinct character compared to the adjoining northern and southern blocks. The study revealed the presence of two Precambrian mega lineaments over a stretch of 750–800 km running in east-west direction...

  2. Organizational Life Cycles and Shifting Criteria of Effectiveness: Some Preliminary Evidence

    OpenAIRE

    Robert E. Quinn; Kim Cameron

    1983-01-01

    This paper discusses the relationships between stage of development in organizational life cycles and organizational effectiveness. We begin the paper by reviewing nine models of organizational life cycles that have been proposed in the literature. Each of these models identifies certain characteristics that typify organizations in different stages of development. A summary model of life cycle stages is derived that integrates each of these nine models. Next, a framework of organizational eff...

  3. Preliminary Evidence for a Classroom Based Psychosocial Intervention for Disaster Exposed Children with Posttraumatic Stress Symptomatology

    Science.gov (United States)

    Rønholt, Stine; Karsberg, Sidsel; Elklit, Ask

    2013-01-01

    Background: In 2004, a firework factory in a residential area of a large Danish city exploded. The children at the local school were screened for symptoms of posttraumatic stress disorder (PTSD) 16 months and 3½ years after the incident. A large proportion of the children still suffered from a substantial number of symptoms 3½ years after the…

  4. Development of an Online and Offline Integration Hypothesis for Healthy Internet Use: Theory and Preliminary Evidence

    Science.gov (United States)

    Lin, Xiaoyan; Su, Wenliang; Potenza, Marc N.

    2018-01-01

    The Internet has become an integral part of our daily life, and how to make the best use of the Internet is important to both individuals and the society. Based on previous studies, an Online and Offline Integration Hypothesis is proposed to suggest a framework for considering harmonious and balanced Internet use. The Integration Hypothesis proposes that healthier patterns of Internet usage may be achieved through harmonious integration of people’s online and offline worlds. An online/offline integration is proposed to unite self-identity, interpersonal relationships, and social functioning with both cognitive and behavioral aspects by following the principles of communication, transfer, consistency, and “offline-first” priorities. To begin to test the hypothesis regarding the relationship between integration level and psychological outcomes, data for the present study were collected from 626 undergraduate students (41.5% males). Participants completed scales for online and offline integration, Internet addiction, pros and cons of Internet use, loneliness, extraversion, and life satisfaction. The findings revealed that subjects with higher level of online/offline integration have higher life satisfaction, greater extraversion, and more positive perceptions of the Internet and less loneliness, lower Internet addiction, and fewer negative perceptions of the Internet. Integration mediates the link between extraversion and psychological outcomes, and it may be the mechanism underlying the difference between the “rich get richer” and social compensation hypotheses. The implications of the online and offline integration hypothesis are discussed.

  5. Measures of Hindu pathways: development and preliminary evidence of reliability and validity.

    Science.gov (United States)

    Tarakeshwar, Nalini; Pargament, Kenneth I; Mahoney, Annette

    2003-11-01

    The authors examined religious practices of Hindus in the United States and developed measures of their religious pathways. Based on reviews of the psychology of religion, Hindu literature, and interviews with Hindus (N=15), 4 religious pathways were identified: devotion, ethical action, knowledge, and physical restraint/yoga. Items reflecting these pathways were generated and administered to a pilot sample (N=42) and then mailed to a sample across the United States (N=182). Consistent with Hindu theology, participants endorsed 4 religious pathways. Results indicated that the measures of the religious pathways possessed adequate psychometric properties and were predictive of mental and physical well-being. Additional findings emphasized the need to attend to age, marital status, and acculturation when studying religious practices among Hindus.

  6. Brief Self-Efficacy Scales for use in Weight-Loss Trials: Preliminary Evidence of Validity

    Science.gov (United States)

    Wilson, Kathryn E.; Harden, Samantha M.; Almeida, Fabio A.; You, Wen; Hill, Jennie L.; Goessl, Cody; Estabrooks, Paul A.

    2015-01-01

    Self-efficacy is a commonly included cognitive variable in weight-loss trials, but there is little uniformity in its measurement. Weight-loss trials frequently focus on physical activity (PA) and eating behavior, as well as weight loss, but no survey is available that offers reliable measurement of self-efficacy as it relates to each of these targeted outcomes. The purpose of this study was to test the psychometric properties of brief, pragmatic self-efficacy scales specific to PA, healthful eating and weight-loss (4 items each). An adult sample (n=1790) from 28 worksites enrolled in a worksite weight-loss program completed the self-efficacy scale, as well as measures of PA, dietary fat intake, and weight, at baseline, 6-, and 12-months. The hypothesized factor structure was tested through confirmatory factor analysis, which supported the expected factor structure for three latent self-efficacy factors, specific to PA, healthful eating, and weight-loss. Measurement equivalence/invariance between relevant demographic groups, and over time was also supported. Parallel growth processes in self-efficacy factors and outcomes (PA, fat intake, and weight) support the predictive validity of score interpretations. Overall, this initial series of psychometric analyses supports the interpretation that scores on these scales reflect self-efficacy for PA, healthful eating, and weight-loss. The use of this instrument in large-scale weight-loss trials is encouraged. PMID:26619093

  7. EVIDENCE OF A GUADALUPIAN AGE FOR THE KHUFF FORMATION OF SOUTHEASTERN OMAN: PRELIMINARY REPORT

    Directory of Open Access Journals (Sweden)

    LUCIA ANGIOLINI

    1998-11-01

    Full Text Available The Guadalupian succession of the Huqf area (Sultanate of Oman represents a mega-sequence comprising the fluvial terrigenous Gharif Formation and the overlying marine Khuff Formation. The Khuff Fm. is subdivided into four members and is composed of marls and bioclastic limestones. The Khuff Fm. yields a rich fauna of brachiopods, conodonts, foraminifers, bivalves, gastropods, ostracods and cephalopods. The brachiopod fauna of the Khuff Fm. includes strophomenids, productids, orthids and terebratulids. The associated conodont fauna includes Hindeodus excavatus Behnken, Merrilina sp., M. praedivergens Kozur & Mostler, and Sweetina n. sp. (systematic descriptions of conodonts are given in the Paleontological Appendix. Foraminifers are represented by species of Miliolina and Rotaliina. The Khuff Fm. is given a Wordian age, based on brachiopods and conodonts. The depositional environment of the Khuff Fm. of southeastern Oman corresponds to the outer shelf of a large carbonate platform covering most of the Arabian Platform. The Khuff Fm. is interpreted as a major transgressive-regressive cycle related to differential subsidence. 

  8. Preliminary Evidence on the Effectiveness of Psychological Treatments Delivered at a University Counseling Center

    Science.gov (United States)

    Minami, Takuya; Davies, D. Robert; Tierney, Sandra Callen; Bettmann, Joanna E.; McAward, Scott M.; Averill, Lynnette A.; Huebner, Lois A.; Weitzman, Lauren M.; Benbrook, Amy R.; Serlin, Ronald C.; Wampold, Bruce E.

    2009-01-01

    Treatment data from a university counseling center (UCC) that utilized the Outcome Questionnaire-45.2 (OQ-45; M. J. Lambert et al., 2004), a self-report general clinical symptom measure, was compared against treatment efficacy benchmarks from clinical trials of adult major depression that utilized similar measures. Statistical analyses suggested…

  9. MMPI-2: cluster analysis of personality profiles in perinatal depression—preliminary evidence.

    Science.gov (United States)

    Meuti, Valentina; Marini, Isabella; Grillo, Alessandra; Lauriola, Marco; Leone, Carlo; Giacchetti, Nicoletta; Aceti, Franca

    2014-01-01

    To assess personality characteristics of women who develop perinatal depression. The study started with a screening of a sample of 453 women in their third trimester of pregnancy, to which was administered a survey data form, the Edinburgh Postnatal Depression Scale (EPDS) and the Minnesota Multiphasic Personality Inventory 2 (MMPI-2). A clinical group of subjects with perinatal depression (PND, 55 subjects) was selected; clinical and validity scales of MMPI-2 were used as predictors in hierarchical cluster analysis carried out. The analysis identified three clusters of personality profile: two "clinical" clusters (1 and 3) and an "apparently common" one (cluster 2). The first cluster (39.5%) collects structures of personality with prevalent obsessive or dependent functioning tending to develop a "psychasthenic" depression; the third cluster (13.95%) includes women with prevalent borderline functioning tending to develop "dysphoric" depression; the second cluster (46.5%) shows a normal profile with a "defensive" attitude, probably due to the presence of defense mechanisms or to the fear of stigma. Characteristics of personality have a key role in clinical manifestations of perinatal depression; it is important to detect them to identify mothers at risk and to plan targeted therapeutic interventions.

  10. MMPI-2: Cluster Analysis of Personality Profiles in Perinatal Depression—Preliminary Evidence

    OpenAIRE

    Meuti, Valentina; Marini, Isabella; Grillo, Alessandra; Lauriola, Marco; Leone, Carlo; Giacchetti, Nicoletta; Aceti, Franca

    2014-01-01

    Background. To assess personality characteristics of women who develop perinatal depression. Methods. The study started with a screening of a sample of 453 women in their third trimester of pregnancy, to which was administered a survey data form, the Edinburgh Postnatal Depression Scale (EPDS) and the Minnesota Multiphasic Personality Inventory 2 (MMPI-2). A clinical group of subjects with perinatal depression (PND, 55 subjects) was selected; clinical and validity scales of MMPI-2 were used a...

  11. Effect of Biological Relatedness on Perfume Selection for Others: Preliminary Evidence.

    Science.gov (United States)

    Sobotková, Markéta; Fialová, Jitka; Roberts, S Craig; Havlíček, Jan

    2017-01-01

    People tend to choose perfumes to complement their body odour. As kin share some body odour qualities, their ability to select complementary perfumes for relatives might be higher compared with selection for nonrelatives. We tested this in two studies, comparing selection of a perfume for a target man by himself and by either a familiar but unrelated individual (girlfriend; Study 1) or a relative (sister; Study 2). Target men applied the two perfumes (own or other's choice) to their axillae and then wore cotton pads for 12 hr. Collected perfume-body odour blends and perfumes alone were assessed by rater panels. In Study 1, the blends were rated as nominally more pleasant when body odours were mixed with the perfumes selected by girlfriends compared with those selected by target men themselves. In Study 2, body odours mixed with perfumes selected by sisters were rated significantly more attractive than those mixed with perfumes selected by target men. No significant differences were found for attractiveness and pleasantness ratings when perfumes were rated alone, suggesting that it was the resulting blends that were uniquely different. Our results indicate that sisters might be particularly tuned to select suitable perfumes for their siblings.

  12. Teaching with Evidence

    Science.gov (United States)

    Crocco, Margaret; Halvorsen, Anne-Lise; Jacobsen, Rebecca; Segall, Avner

    2017-01-01

    In this age of real and fake news, students need to be able to assess the trustworthiness of evidence. The authors' current research examines students' use of evidence in secondary social studies classrooms as students deliberate contemporary public policy issues. The authors found that students shifted their evaluations of the trustworthiness of…

  13. Hermeneutics, evidence ad judgment

    Directory of Open Access Journals (Sweden)

    Michele Taruffo

    2018-03-01

    Full Text Available The text analyzes several topics of the judicial process from the point of view of the important contributions offered by the hermeneutical philosophy. It deals mainly with the construction of factual narratives, the presentation of evidence and the discovery of truth made by the judge in his final judgment based upon the evidence.

  14. Observational Evidence for Atoms.

    Science.gov (United States)

    Jones, Edwin R., Jr.; Childers, Richard L.

    1984-01-01

    Discusses the development of the concept of atomicity and some of the many which can be used to establish its validity. Chemical evidence, evidence from crystals, Faraday's law of electrolysis, and Avogadro's number are among the areas which show how the concept originally developed from a purely philosophical idea. (JN)

  15. Evidence-based radiography

    International Nuclear Information System (INIS)

    Hafslund, Bjorg; Clare, Judith; Graverholt, Birgitte; Wammen Nortvedt, Monica

    2008-01-01

    Evidence-based practice (EBP) offers the integration of the best research evidence with clinical knowledge and expertise and patient values. EBP is a well known term in health care. This paper discusses the implementation of EBP into radiography and introduces the term evidence-based radiography. Evidence-based radiography is radiography informed and based on the combination of clinical expertise and the best available research-based evidence, patient preferences and resources available. In Norway, EBP in radiography is being debated and radiographers are discussing the challenges of implementing EBP in both academic and clinical practice. This discussion paper explains why EBP needs to be a basis for a radiography curriculum and a part of radiographers' practice. We argue that Norwegian radiographers must increase participation in research and developing practice within their specific radiographic domain

  16. The Industrious Revolution and Early Modern Colonial Goods Trade - Evidence from the Soundtoll Online Database

    NARCIS (Netherlands)

    Uebele, Martin

    2013-01-01

    This article presents preliminary evidence of the volume of coffee trade tolled at the entry to the Baltic Sea, ca. 1700-1850, using the Soundtoll Registers Online Database (www.soundtoll.nl). The results are interpreted in the light of the “Industrious Revolution” hypothesis (De Vries 2008). The

  17. Preliminary design of a coffee harvester

    Directory of Open Access Journals (Sweden)

    Raphael Magalhães Gomes Moreira

    2016-10-01

    Full Text Available Design of an agricultural machine is a highly complex process due to interactions between the operator, machine, and environment. Mountain coffee plantations constitute an economic sector that requires huge investments for the development of agricultural machinery to improve the harvesting and post-harvesting processes and to overcome the scarcity of work forces in the fields. The aim of this study was to develop a preliminary design for a virtual prototype of a coffee fruit harvester. In this study, a project methodology was applied and adapted for the development of the following steps: project planning, informational design, conceptual design, and preliminary design. The construction of a morphological matrix made it possible to obtain a list of different mechanisms with specific functions. The union between these mechanisms resulted in variants, which were weighed to attribute scores for each selected criterion. From each designated proposal, two variants with the best scores were selected and this permitted the preparation of the preliminary design of both variants. The archetype was divided in two parts, namely the hydraulically articulated arms and the harvesting system that consisted of the vibration mechanism and the detachment mechanism. The proposed innovation involves the use of parallel rods, which were fixed in a plane and rectangular metal sheet. In this step, dimensions including a maximum length of 4.7 m, a minimum length of 3.3 m, and a total height of 2.15 m were identified based on the functioning of the harvester in relation to the coupling point of the tractor.

  18. Preliminary study on AC superconducting machines

    International Nuclear Information System (INIS)

    Yamamoto, M.; Ishigohka, T.; Shimohka, T.; Mizukami, N.; Yamaguchi, M.

    1988-01-01

    This paper describes the issues involved in developing AC superconducting machines. In the first phase, as a preliminary experiment, a 4kVa AC superconducting coil which employs 100A class 50/60Hz superconductors is made and tested. And, in the second phase, as an extension of the 4kVa coil, a model superconducting transformer is made and examined. The transformer has a novel quench protection system with an auxiliary coil only in the low voltage side. The behavior of the overcurrent protection system is confirmed

  19. Mineral matter in Mozambique coals - preliminary note

    Energy Technology Data Exchange (ETDEWEB)

    Aires-Borros, L.; Lemos de Sousa, M.J.; Furtado, S.

    1984-01-01

    The importance of mineral matter which occurs in coals as plant ash (trace elements), mineral inclusions, and as discrete band of dirt or partings within the seams, is discussed. A preliminary research of the mineralogical composition of the discrete bands occurring in coal seams from Moatize-Minjova and Chicoa-Mecucoe coalfields, Zambezi Valley, People's Republic of Mozambique, showed the occurrence of the following minerals: kaolinite; illite with more or less complex stratified species, namely montmorillonite; quartz; carbonates and iron oxides.

  20. Preliminary list of plant invaders in Montenegro

    Directory of Open Access Journals (Sweden)

    Stešević, D.

    2010-12-01

    Full Text Available Due to the fact that Invasive alien species (IAS are considered to be the second cause of global biodiversity loss after direct habitat destruction and have adverse environmental, economic and social impacts from the local level upwards, in last decades investigations of alien flora of Montenegro are intensified. In this paper we are presenting a preliminary list of IAS, with the aim to provide a basic data on IAS in Montenegro, to enable future monitoring and to draw attention on the problems which expansion of IAS is bringing with itself. The list consists of 50 plant taxa species and supspecies level.

  1. Preliminary recommendations of the Noise Working Group

    International Nuclear Information System (INIS)

    Legerton, M.L.

    1995-01-01

    In 1993 the DTI set up a Working Group largely consisting of independent experts on wind turbine noise. The main objectives of the Working Group were to define a framework which can be used to measure and rate the noise from wind turbines and to provide indicative noise levels thought to offer a reasonable degree of protection to wind farm neighbours and encourage best practice in turbine design and wind farm siting and layout. This paper presents the preliminary recommendations of the Working Group. (Author)

  2. Preliminary economic evaluation of the Alkox process

    International Nuclear Information System (INIS)

    Silva, L.J.; Lilga, M.A.; Camaioni, D.M.; Snowden, L.J.

    1991-09-01

    A new chemical process has been invented at Battelle Pacific Northwest Laboratories for converting alkanes to alcohols. This new chemistry has been named the ''Alkox Process.'' Pacific Northwest Laboratory prepared a preliminary economic analysis for converting cyclohexane to cyclohexanol, which may be one of the most attractive applications of the Alkox process. A process flow scheme and a material balance were prepared to support rough equipment sizing and costing. The results from the economic analysis are presented in the non-proprietary section of this report. The process details, including the flow diagram and material balance, are contained in separate section of this report that is proprietary to Battelle. 7 refs., 4 tabs

  3. Preliminary Cost Model for Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip; Prince, F. Andrew; Smart, Christian; Stephens, Kyle; Henrichs, Todd

    2009-01-01

    Parametric cost models are routinely used to plan missions, compare concepts and justify technology investments. However, great care is required. Some space telescope cost models, such as those based only on mass, lack sufficient detail to support such analysis and may lead to inaccurate conclusions. Similarly, using ground based telescope models which include the dome cost will also lead to inaccurate conclusions. This paper reviews current and historical models. Then, based on data from 22 different NASA space telescopes, this paper tests those models and presents preliminary analysis of single and multi-variable space telescope cost models.

  4. Preliminary safety assessment of the WIPP facility

    International Nuclear Information System (INIS)

    Balestri, R.J.; Torres, B.W.; Pahwa, S.B.; Brannen, J.P.

    1979-01-01

    The efforts to perform a safety assessment of the WIPP facility being proposed for southeastern New Mexico are summarized. This preliminary safety assessment of the WIPP facility is limited to a consequence assessment in terms of the dose to a maximally exposed individual as a result of introducing the radionuclides into the biosphere. No attempt has been made to extend the consequences to population dose or to weight the dose with probability of the events. The general methodology, geosphere transport, and biosphere transport are described. The consequences of the various models developed to represent the loss of containment are summarized

  5. Preliminary cost estimating for the nuclear industry

    International Nuclear Information System (INIS)

    Klumpar, I.V.; Soltz, K.M.

    1985-01-01

    The nuclear industry has higher costs for personnel, equipment, construction, and engineering than conventional industry, which means that cost estimation procedures may need adjustment. The authors account for the special technical and labor requirements of the nuclear industry in making adjustments to equipment and installation cost estimations. Using illustrative examples, they show that conventional methods of preliminary cost estimation are flexible enough for application to emerging industries if their cost structure is similar to that of the process industries. If not, modifications can provide enough engineering and cost data for a statistical analysis. 9 references, 14 figures, 4 tables

  6. Preliminary Clinical Study On Ms Treatment With Hyperbaric Oxygenation

    Directory of Open Access Journals (Sweden)

    Ulewicz Kazimierz

    2015-06-01

    Full Text Available The authors conducted the preliminary clinical investigation on 16 multiple sclerosis (Sclerosis multiplex patients of median disease duration 9.33 years and symptoms evaluated on Kurtzke’s scale. The patients underwent between 25 and 30 hyperbaric oxygen exposures at a pressure of 2 ata in intervals spread over a few days. The patients were qualified and classified to the treatment symptomatologically according to Fisher but the obtained results were evaluated according to the standardised Disability Status Scale by Kurtzke. During the investigations the authors carried out additional quantitative immunoglobulin and complement activity determination, lymphocyte T and B determinations as well as the usually applied clinical and laboratory investigations. Evident clinical improvement was observed in 14 patients, but in the case of one patient a deterioration was observed after 15 hyperbaric expositions (resulting in the hyperbaric oxygen treatment being stopped, whilst in another case no curative effect could be observed. By utilising the 50% haemolysis method, within the examined immunological parameters the authors observed an increase of complement fractions and its activity, white lymphocytes T and B examined qualitatively did not maintain the characteristic shift. The authors are still discussing the obtained results.

  7. Establishment and preliminary outcomes of a palliative care research network.

    Science.gov (United States)

    Hudson, Peter; Street, Annette; Graham, Suzanne; Aranda, Sanchia; O'Connor, Margaret; Thomas, Kristina; Jackson, Kate; Spruyt, Odette; Ugalde, Anna; Philip, Jennifer

    2016-02-01

    The difficulties in conducting palliative care research have been widely acknowledged. In order to generate the evidence needed to underpin palliative care provision, collaborative research is considered essential. Prior to formalizing the development of a research network for the state of Victoria, Australia, a preliminary study was undertaken to ascertain interest and recommendations for the design of such a collaboration. Three data-collection strategies were used: a cross-sectional questionnaire, interviews, and workshops. The questionnaire was completed by multidisciplinary palliative care specialists from across the state (n = 61); interviews were conducted with senior clinicians and academics (n = 21) followed by two stakeholder workshops (n = 29). The questionnaire was constructed specifically for this study, measuring involvement of and perceptions of palliative care research. Both the interview and the questionnaire data demonstrated strong support for a palliative care research network and aided in establishing a research agenda. The stakeholder workshops assisted with strategies for the formation of the Palliative Care Research Network Victoria (PCRNV) and guided the development of the mission and strategic plan. The research and efforts to date to establish the PCRNV are encouraging and provide optimism for the evolution of palliative care research in Australia. The international implications are highlighted.

  8. Preliminary report: The Little Skull Mountain earthquake, June 29, 1992

    International Nuclear Information System (INIS)

    Anderson, J.G.; Brune, J.N.; Polo, D. de; Savage, M.K.; Sheehan, A.F.; Smith, K.D.; Gomberg, J.; Harmsen, S.C.

    1993-01-01

    The Little Skull Mountain earthquake occurred about 20 km from the potential high level nuclear repository at Yucca Mountain. The magnitude was 5.6, and the focal mechanism indicates normal faulting on a northeast trending structure. There is evidence that the earthquake was triggered by the magnitude M S = 7.5 earthquake in Landers, California, which occurred less than 24 hours earlier. Preliminary locations of the hypocenter and several aftershocks define an L shaped pattern near the southern boundary of the Nevada Test Site. One arm trends to the northeast beneath Little Skull Mountain, and a shorter, more diffuse zone trends to the southeast. The aftershocks are mostly located at depths between 7 km and 11 km, and may suggest a southeast dipping plane. There is no clear correlation with previously mapped surface faulting. The strongest recorded acceleration is about 0.21 g at Lathrop Wells, Nevada, 15 km from the epicenter. An extensive network of aftershock recorders was installed by the Seismological Laboratory, University of Nevada, Reno, by the US Geological Survey, Golden, Colorado, and by Lawrence Livermore Laboratory, Livermore, California. Aftershock experiments are ongoing as of November, 1992, and include experiments to improve location, depth, focal mechanism, and stress drop, study basin and ridge response near the epicenter and at Midway Valley, and study response of a tunnel at Little Skull Mountain. Analysis of this data, which includes thousands of aftershocks, has only begun

  9. Crystallization and preliminary crystallographic analysis of recombinant human galectin-1

    Energy Technology Data Exchange (ETDEWEB)

    Scott, Stacy A. [Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland 4222 (Australia); Scott, Ken [School of Biological Sciences, University of Auckland, Auckland (New Zealand); Blanchard, Helen, E-mail: h.blanchard@griffith.edu.au [Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland 4222 (Australia)

    2007-11-01

    Human galectin-1 has been cloned, expressed in E. coli, purified and crystallized in the presence of both lactose (ligand) and β-mercaptoethanol under six different conditions. The X-ray diffraction data obtained have enabled the assignment of unit-cell parameters for two novel crystal forms of human galectin-1. Galectin-1 is considered to be a regulator protein as it is ubiquitously expressed throughout the adult body and is responsible for a broad range of cellular regulatory functions. Interest in galectin-1 from a drug-design perspective is founded on evidence of its overexpression by many cancers and its immunomodulatory properties. The development of galectin-1-specific inhibitors is a rational approach to the fight against cancer because although galectin-1 induces a plethora of effects, null mice appear normal. X-ray crystallographic structure determination will aid the structure-based design of galectin-1 inhibitors. Here, the crystallization and preliminary diffraction analysis of human galectin-1 crystals generated under six different conditions is reported. X-ray diffraction data enabled the assignment of unit-cell parameters for crystals grown under two conditions, one belongs to a tetragonal crystal system and the other was determined as monoclinic P2{sub 1}, representing two new crystal forms of human galectin-1.

  10. Development and preliminary validation of a scale to measure patient uncertainty: The "Uncertainty Scale".

    Science.gov (United States)

    LaNoue, Marianna D; Gerolamo, Angela M; Powell, Rhea; Nord, Garrison; Doty, Amanda Mb; Rising, Kristin L

    2018-01-01

    Research suggests that patient uncertainty related to experiencing symptoms may drive decisions to seek care. The only validated measure of patient uncertainty assesses uncertainty related to defined illness. In prior work, we engaged patients to describe uncertainty related to symptoms and used findings to develop the 'U-Scale' scale. In this work, we present results from preliminary scale reliability and validity testing. Psychometric testing demonstrated content validity, high internal consistency, and evidence for concurrent validity. Next steps include administration in diverse populations for continued refinement and validation, and exploration of the potential contribution of uncertainty to healthcare utilization.

  11. Evidence-Based Development

    DEFF Research Database (Denmark)

    Hertzum, Morten; Simonsen, Jesper

    2004-01-01

    Systems development is replete with projects that represent substantial resource investments but result in systems that fail to meet users’ needs. Evidence-based development is an emerging idea intended to provide means for managing customer-vendor relationships and working systematically toward...... and electronic patient records for diabetes patients, this paper reports research in progress regarding the prospects and pitfalls of evidence-based development....

  12. Building Bridges to the Economic Mainstream for African American Male Ex-Offenders: A Preliminary Assessment of an Inmate Education Re-Entry Program.

    Science.gov (United States)

    Johnson, James H., Jr.; Farrell, Walter C., Jr.; Braithwaite, Lawrence P.

    This paper describes a state-funded inmate education and re-entry program that provides soft skills training for soon-to-be released offenders. The paper presents preliminary evidence regarding the impact of this training on 14 young male participants. Data came from information prepared by inmates throughout the training program and ethnographic…

  13. A Preliminary Report on a New Measure: Internalization of the Model Minority Myth Measure (IM-4) and Its Psychological Correlates among Asian American College Students

    Science.gov (United States)

    Yoo, Hyung Chol; Burrola, Kimberly S.; Steger, Michael F.

    2010-01-01

    This investigation is a preliminary report on a new measure of internalization of the model minority myth. In 3 studies, there was evidence for the validation of the 15-item Internalization of the Model Minority Myth Measure (IM-4), with 2 subscales. The Model Minority Myth of Achievement Orientation referred to the myth of Asian Americans'…

  14. Defining resilience: A preliminary integrative literature review

    Science.gov (United States)

    Wilt, Bonnie; Long, Suzanna K.; Shoberg, Thomas G.

    2016-01-01

    The term “resilience” is ubiquitous in technical literature; it appears in numerous forms, such as resilience, resiliency, or resilient, and each use may have a different definition depending on the interpretation of the writer. This creates difficulties in understanding what is meant by ‘resilience’ in any given use case, especially in discussions of interdisciplinary research. To better understand this problem, this research constructs a preliminary integrative literature review to map different definitions, applications and calculation methods of resilience invoked within critical infrastructure applications. The preliminary review uses a State-of-the-Art Matrix (SAM) analysis to characterize differences in definition across disciplines and between regions. Qualifying the various usages of resilience will produce a greater precision in the literature and a deeper insight into types of data required for its evaluation, particularly with respect to critical infrastructure calculations and how such data may be analyzed. Results from this SAM analysis will create a framework of key concepts as part of the most common applications for “resilient critical infrastructure” modeling.

  15. Preliminary impression techniques for microstomia patients

    Directory of Open Access Journals (Sweden)

    K Aswini Kumar

    2016-01-01

    Full Text Available The Prosthetic rehabilitation of microstomia patients presents difficulties at all the stages. The difficulty starts with the preliminary impression making. This is due to the tongue rigidity and the decreased oral opening. A maximum oral opening which is smaller than the size of the tray can make prosthetic treatment challenging. Due to the restricted mouth opening, insertion and removal of the impression trays is extremely cumbersome and various modifications of the trays have been used in the past. Among these are the flexible trays and the sectional trays used with different modes of reassembling the segments extra orally after the impression is made. This article reviews the literature published from 1971 to 2015 concerning preliminary impression techniques used in making impressions for patients with microstomia based on various tray designs. An electronic search was performed across three databases (PubMed, Science Direct and Google Scolar for relevant citations. The keywords/combinations used for the search were microstomia, limited/constricted/restricted mouth opening/oral access, trismus, sectional trays, impressions and prosthetic/prosthodontic rehabilitation. The search was limited to papers written in English which resulted in a total of 45 related articles of which 17 articles were included for discussion of this review.

  16. Preliminary design for a maglev development facility

    Energy Technology Data Exchange (ETDEWEB)

    Coffey, H.T.; He, J.L.; Chang, S.L.; Bouillard, J.X.; Chen, S.S.; Cai, Y.; Hoppie, L.O.; Lottes, S.A.; Rote, D.M. [Argonne National Lab., IL (United States); Zhang, Z.Y. [Polytechnic Univ., Brooklyn, NY (United States); Myers, G.; Cvercko, A. [Sterling Engineering, Westchester, IL (United States); Williams, J.R. [Alfred Benesch and Co., Chicago, IL (United States)

    1992-04-01

    A preliminary design was made of a national user facility for evaluating magnetic-levitation (maglev) technologies in sizes intermediate between laboratory experiments and full-scale systems. A technical advisory committee was established and a conference was held to obtain advice on the potential requirements of operational systems and how the facility might best be configured to test these requirements. The effort included studies of multiple concepts for levitating, guiding, and propelling maglev vehicles, as well as the controls, communications, and data-acquisition and -reduction equipment that would be required in operating the facility. Preliminary designs for versatile, dual 2-MVA power supplies capable of powering attractive or repulsive systems were developed. Facility site requirements were identified. Test vehicles would be about 7.4 m (25 ft) long, would weigh form 3 to 7 metric tons, and would operate at speeds up to 67 m/s (150 mph) on a 3.3-km (2.05-mi) elevated guideway. The facility would utilize modular vehicles and guideways, permitting the substitution of levitation, propulsion, and guideway components of different designs and materials for evaluation. The vehicle would provide a test cell in which individual suspension or propulsion components or subsystems could be tested under realistic conditions. The system would allow economical evaluation of integrated systems under varying weather conditions and in realistic geometries.

  17. A preliminary neutron crystallographic study of thaumatin

    Energy Technology Data Exchange (ETDEWEB)

    Teixeira, Susana C. M. [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); Blakeley, Matthew P. [Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); Leal, Ricardo M. F. [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); ESRF, 6 Rue Jules Horowitz, BP-220, 38043 Grenoble (France); Mitchell, Edward P. [EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); ESRF, 6 Rue Jules Horowitz, BP-220, 38043 Grenoble (France); Forsyth, V. Trevor, E-mail: tforsyth@ill.fr [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom)

    2008-05-01

    Preliminary neutron crystallographic data from the sweet protein thaumatin have been recorded using the LADI-III diffractometer at the Institut Laue Langevin (ILL). The results illustrate the feasibility of a full neutron structural analysis aimed at further understanding the molecular basis of the perception of sweet taste. Such an analysis will exploit the use of perdeuterated thaumatin. A preliminary neutron crystallographic study of the sweet protein thaumatin is presented. Large hydrogenated crystals were prepared in deuterated crystallization buffer using the gel-acupuncture method. Data were collected to a resolution of 2 Å on the LADI-III diffractometer at the Institut Laue Langevin (ILL). The results demonstrate the feasibility of a full neutron crystallographic analysis of this structure aimed at providing relevant information on the location of H atoms, the distribution of charge on the protein surface and localized water in the structure. This information will be of interest for understanding the specificity of thaumatin–receptor interactions and will contribute to further understanding of the molecular mechanisms underlying the perception of taste.

  18. Preliminary Hazards Analysis Plasma Hearth Process

    International Nuclear Information System (INIS)

    Aycock, M.; Coordes, D.; Russell, J.; TenBrook, W.; Yimbo, P.

    1993-11-01

    This Preliminary Hazards Analysis (PHA) for the Plasma Hearth Process (PHP) follows the requirements of United States Department of Energy (DOE) Order 5480.23 (DOE, 1992a), DOE Order 5480.21 (DOE, 1991d), DOE Order 5480.22 (DOE, 1992c), DOE Order 5481.1B (DOE, 1986), and the guidance provided in DOE Standards DOE-STD-1027-92 (DOE, 1992b). Consideration is given to ft proposed regulations published as 10 CFR 830 (DOE, 1993) and DOE Safety Guide SG 830.110 (DOE, 1992b). The purpose of performing a PRA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PRA then is followed by a Preliminary Safety Analysis Report (PSAR) performed during Title I and II design. This PSAR then leads to performance of the Final Safety Analysis Report performed during construction, testing, and acceptance and completed before routine operation. Radiological assessments indicate that a PHP facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous material assessments indicate that a PHP facility will be a Low Hazard facility having no significant impacts either onsite or offsite to personnel and the environment

  19. Business System Planning Project, Preliminary System Design

    International Nuclear Information System (INIS)

    EVOSEVICH, S.

    2000-01-01

    CH2M HILL Hanford Group, Inc. (CHG) is currently performing many core business functions including, but not limited to, work control, planning, scheduling, cost estimating, procurement, training, and human resources. Other core business functions are managed by or dependent on Project Hanford Management Contractors including, but not limited to, payroll, benefits and pension administration, inventory control, accounts payable, and records management. In addition, CHG has business relationships with its parent company CH2M HILL, U.S. Department of Energy, Office of River Protection and other River Protection Project contractors, government agencies, and vendors. The Business Systems Planning (BSP) Project, under the sponsorship of the CH2M HILL Hanford Group, Inc. Chief Information Officer (CIO), have recommended information system solutions that will support CHG business areas. The Preliminary System Design was developed using the recommendations from the Alternatives Analysis, RPP-6499, Rev 0 and will become the design base for any follow-on implementation projects. The Preliminary System Design will present a high-level system design, providing a high-level overview of the Commercial-Off-The-Shelf (COTS) modules and identify internal and external relationships. This document will not define data structures, user interface components (screens, reports, menus, etc.), business rules or processes. These in-depth activities will be accomplished at implementation planning time

  20. Preliminary remediation goals for ecological endpoints

    International Nuclear Information System (INIS)

    Efroymson, R.A.; Suter, G.W. II; Sample, B.E.; Jones, D.S.

    1996-07-01

    Preliminary remediation goals (PRGs) are useful for risk assessment and decision making at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites. PRGs are upper concentration limits for specific chemicals in specific environmental media that are anticipated to protect human health or the environment. They can be used for multiple remedial investigations at multiple facilities. In addition to media and chemicals of potential concern, the development of PRGs generally requires some knowledge or anticipation of future land use. In Preliminary Remediation Goals for Use at the U.S. Department of Energy Oak Ridge Operations Office (Energy Systems 1995), PRGs intended to protect human health were developed with guidance from Risk Assessment Guidance for Superfund: Volume I - Human Health Evaluation Manual, Part B (RAGS) (EPA 1991). However, no guidance was given for PRGs based on ecological risk. The numbers that appear in this volume have, for the most part, been extracted from toxicological benchmarks documents for Oak Ridge National Laboratory (ORNL) and have previously been developed by ORNL. The sources of the quantities, and many of the uncertainties associated with their derivation, are described in this technical memorandum

  1. Preliminary remediation goals for ecological endpoints

    Energy Technology Data Exchange (ETDEWEB)

    Efroymson, R.A.; Suter, G.W. II; Sample, B.E.; Jones, D.S.

    1996-07-01

    Preliminary remediation goals (PRGs) are useful for risk assessment and decision making at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites. PRGs are upper concentration limits for specific chemicals in specific environmental media that are anticipated to protect human health or the environment. They can be used for multiple remedial investigations at multiple facilities. In addition to media and chemicals of potential concern, the development of PRGs generally requires some knowledge or anticipation of future land use. In Preliminary Remediation Goals for Use at the U.S. Department of Energy Oak Ridge Operations Office (Energy Systems 1995), PRGs intended to protect human health were developed with guidance from Risk Assessment Guidance for Superfund: Volume I - Human Health Evaluation Manual, Part B (RAGS) (EPA 1991). However, no guidance was given for PRGs based on ecological risk. The numbers that appear in this volume have, for the most part, been extracted from toxicological benchmarks documents for Oak Ridge National Laboratory (ORNL) and have previously been developed by ORNL. The sources of the quantities, and many of the uncertainties associated with their derivation, are described in this technical memorandum.

  2. Ship design methodologies of preliminary design

    CERN Document Server

    Papanikolaou, Apostolos

    2014-01-01

    This book deals with ship design and in particular with methodologies of the preliminary design of ships. The book is complemented by a basic bibliography and five appendices with useful updated charts for the selection of the main dimensions and other basic characteristics of different types of ships (Appendix A), the determination of hull form  from the data of systematic hull form series (Appendix B), the detailed description of the relational method for the preliminary estimation of ship weights (Appendix C), a brief review of the historical evolution of shipbuilding science and technology from the prehistoric era to date (Appendix D) and finally a historical review of regulatory developments of ship's damage stability to date (Appendix E).  The book can be used as textbook for ship design courses or as additional reading for university or college students of naval architecture courses and related disciplines; it may also serve as a reference book for naval architects, practicing engineers of rel...

  3. Preliminary results of ground-motion characteristics

    Directory of Open Access Journals (Sweden)

    Francesca Bozzoni

    2012-10-01

    Full Text Available The preliminary results are presented herein for the engineering applications of the characteristics of the ground motion induced by the May 20, 2012, Emilia earthquake. Shake maps are computed to provide estimates of the spatial distribution of the induced ground motion. The signals recorded at the Mirandola (MRN station, the closest to the epicenter, have been processed to obtain acceleration, velocity and displacement response spectra. Ground-motion parameters from the MRN recordings are compared with the corresponding estimates from recent ground-motion prediction equations, and with the spectra prescribed by the current Italian Building Code for different return periods. The records from the MRN station are used to plot the particle orbit (hodogram described by the waveform. The availability of results from geotechnical field tests that were performed at a few sites in the Municipality of Mirandola prior to this earthquake of May 2012 has allowed preliminary assessment of the ground response. The amplification effects at Mirandola are estimated using fully stochastic site-response analyses. The seismic input comprises seven actual records that are compatible with the Italian code-based spectrum that refers to a 475-year return period. The computed acceleration response spectrum and the associated dispersion are compared to the spectra calculated from the recordings of the MRN station. Good agreement is obtained for periods up to 1 s, especially for the peak ground acceleration. For the other periods, the spectral acceleration of the MRN recordings exceeds that of the computed spectra.

  4. Preliminary competencies for comparative effectiveness research.

    Science.gov (United States)

    Segal, Jodi B; Kapoor, Wishwa; Carey, Timothy; Mitchell, Pamela H; Murray, Michael D; Saag, Kenneth G; Schumock, Glen; Jonas, Daniel; Steinman, Michael; Filart, Rosemarie; Weinberger, Morris; Selker, Harry

    2012-12-01

    The Clinical and Translational Science Award (CTSA) Workgroup for Comparative Effectiveness Research (CER) Education, Training, and Workforce Development identified a need to delineate the competencies that practitioners and users of CER for patient-centered outcomes research, should acquire. With input from CTSA representatives and collaborators, we began by describing the workforce. We recognize the workforce that conducts CER and the end users who use CER to improve the health of individuals and communities. We generated a preliminary set of competencies and solicited feedback from the CER representatives at each member site of the CTSA consortium. We distinguished applied competencies (i.e., skills needed by individuals who conduct CER) from foundational competencies that are needed by the entire CER workforce, including end users of CER. Key competency categories of relevance to both practitioners and users of CER were: (1) asking relevant research questions; (2) recognizing or designing ideal CER studies; (3) executing or using CER studies; (4) using appropriate statistical analyses for CER; and (5) communicating and disseminating CER study results to improve health. Although CER is particularly broad concept, we anticipate that these preliminary, relatively generic competencies will be used in tailoring curricula to individual learners from a variety of programmatic perspectives. © 2012 Wiley Periodicals, Inc.

  5. Evidence-based dentistry.

    Science.gov (United States)

    Chambers, David W

    2010-01-01

    Both panegyric and criticism of evidence-based dentistry tend to be clumsy because the concept is poorly defined. This analysis identifies several contributions to the profession that have been made under the EBD banner. Although the concept of clinicians integrating clinical epidemiology, the wisdom of their practices, and patients' values is powerful, its implementation has been distorted by a too heavy emphasis of computerized searches for research findings that meet the standards of academics. Although EBD advocates enjoy sharing anecdotal accounts of mistakes others have made, faulting others is not proof that one's own position is correct. There is no systematic, high-quality evidence that EBD is effective. The metaphor of a three-legged stool (evidence, experience, values, and integration) is used as an organizing principle. "Best evidence" has become a preoccupation among EBD enthusiasts. That overlong but thinly developed leg of the stool is critiqued from the perspectives of the criteria for evidence, the difference between internal and external validity, the relationship between evidence and decision making, the ambiguous meaning of "best," and the role of reasonable doubt. The strongest leg of the stool is clinical experience. Although bias exists in all observations (including searches for evidence), there are simple procedures that can be employed in practice to increase useful and objective evidence there, and there are dangers in delegating policy regarding allowable treatments to external groups. Patient and practitioner values are the shortest leg of the stool. As they are so little recognized, their integration in EBD is problematic and ethical tensions exist where paternalism privileges science over patient's self-determined best interests. Four potential approaches to integration are suggested, recognizing that there is virtually no literature on how the "seat" of the three-legged stool works or should work. It is likely that most dentists

  6. Synthesis, photophysical and preliminary investigation of the dye ...

    Indian Academy of Sciences (India)

    Synthesis, photophysical and preliminary investigation of the dye-sensitized solar cells properties of functionalized .... chemistry and preliminary solar cell properties of the complexes. 2. Experimental. 2.1 Materials and ... solvents prior to loading of extract onto the column. (3.5 cm × 8.5cm). Melting points were determined.

  7. A Preliminary Anthropometry Standard for Australian Army Equipment Evaluation

    Science.gov (United States)

    2014-08-01

    UNCLASSIFIED UNCLASSIFIED A Preliminary Anthropometry Standard for Australian Army Equipment Evaluation Mark Edwards, Alistair Furnell...Jemma Coleman and Sheena Davis Land Division Defence Science and Technology Organisation DSTO-TR-3006 ABSTRACT Anthropometry is the...Preliminary Anthropometry Standard for Australian Defence Force Army Equipment Evaluation Executive Summary Anthropometry is the

  8. Preliminary Data From The Adult L2 Acquisition Of Afrikaans

    African Journals Online (AJOL)

    KATEVG

    of the L2. This paper reports preliminary data collected from 9 beginner learners of Afrikaans ... Investigating 'Full Transfer': Preliminary Data From The Adult L2 Acquisition of Afrikaans 3 split up into AgrSP, TP and ..... manipulation task, a grammaticality judgment task, and a short truth-value judgment task. (Examples of the ...

  9. Standing the Test of Time: Reference for a Preliminary Ruling

    DEFF Research Database (Denmark)

    Butler, Graham

    2017-01-01

    It is often too easy to forget just how important the preliminary reference procedure is for the functionality of European Union law. For the Court of Justice, there are both formal and informal means of judicial dialogue. This article focuses on the formal means of dialogue through the preliminary...

  10. Preliminary Opto-Mechanical Design for the X2000 Transceiver

    Science.gov (United States)

    Hemmati, H.; Page, N. A.

    2000-01-01

    Preliminary optical design and mechanical conceptual design for a 30 cm aperture transceiver are described. A common aperture is used for both transmit and receive. Special attention was given to off-axis and scattered light rejection and isolation of the receive channel from the transmit channel. Requirements, details of the design and preliminary performance analysis of the transceiver are provided.

  11. 18 CFR 5.16 - Preliminary licensing proposal.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Preliminary licensing proposal. 5.16 Section 5.16 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE APPLICATION PROCESS § 5.16 Preliminary licensing proposal. (a)...

  12. 37 CFR 1.480 - Demand for international preliminary examination.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Demand for international... Provisions International Preliminary Examination § 1.480 Demand for international preliminary examination. (a) On the filing of a proper Demand in an application for which the United States International...

  13. Evidence based practice

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2011-01-01

    Evidence-based practice (EBP) is an influential interdisciplinary movement that originated in medicine as evidence-based medicine (EBM) about 1992. EBP is of considerable interest to library and information science (LIS) because it focuses on a thorough documentation of the basis for the decision...... making that is established in research as well as an optimization of every link in documentation and search processes. EBP is based on the philosophical doctrine of empiricism and, therefore, it is subject to the criticism that has been raised against empiricism. The main criticism of EBP...... is that practitioners lose their autonomy, that the understanding of theory and of underlying mechanisms is weakened, and that the concept of evidence is too narrow in the empiricist tradition. In this article, it is suggested that we should speak of “research-based practice” rather than EBP, because this term is open...

  14. Evidence-Based Development

    DEFF Research Database (Denmark)

    Hertzum, Morten; Simonsen, Jesper

    2004-01-01

    Systems development is replete with projects that represent substantial resource investments but result in systems that fail to meet users’ needs. Evidence-based development is an emerging idea intended to provide means for managing customer-vendor relationships and working systematically toward...... meeting customer needs. We are suggesting that the effects of the use of a system should play a prominent role in the contractual definition of IT projects and that contract fulfilment should be determined on the basis of evidence of these effects. Based on two ongoing studies of home-care management...

  15. Repository Subsurface Preliminary Fire Hazard Analysis

    International Nuclear Information System (INIS)

    Logan, Richard C.

    2001-01-01

    This fire hazard analysis identifies preliminary design and operations features, fire, and explosion hazards, and provides a reasonable basis to establish the design requirements of fire protection systems during development and emplacement phases of the subsurface repository. This document follows the Technical Work Plan (TWP) (CRWMS M and O 2001c) which was prepared in accordance with AP-2.21Q, ''Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities''; Attachment 4 of AP-ESH-008, ''Hazards Analysis System''; and AP-3.11Q, ''Technical Reports''. The objective of this report is to establish the requirements that provide for facility nuclear safety and a proper level of personnel safety and property protection from the effects of fire and the adverse effects of fire-extinguishing agents

  16. Plasma brake model for preliminary mission analysis

    Science.gov (United States)

    Orsini, Leonardo; Niccolai, Lorenzo; Mengali, Giovanni; Quarta, Alessandro A.

    2018-03-01

    Plasma brake is an innovative propellantless propulsion system concept that exploits the Coulomb collisions between a charged tether and the ions in the surrounding environment (typically, the ionosphere) to generate an electrostatic force orthogonal to the tether direction. Previous studies on the plasma brake effect have emphasized the existence of a number of different parameters necessary to obtain an accurate description of the propulsive acceleration from a physical viewpoint. The aim of this work is to discuss an analytical model capable of estimating, with the accuracy required by a preliminary mission analysis, the performance of a spacecraft equipped with a plasma brake in a (near-circular) low Earth orbit. The simplified mathematical model is first validated through numerical simulations, and is then used to evaluate the plasma brake performance in some typical mission scenarios, in order to quantify the influence of the system parameters on the mission performance index.

  17. Repository Subsurface Preliminary Fire Hazard Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Richard C. Logan

    2001-07-30

    This fire hazard analysis identifies preliminary design and operations features, fire, and explosion hazards, and provides a reasonable basis to establish the design requirements of fire protection systems during development and emplacement phases of the subsurface repository. This document follows the Technical Work Plan (TWP) (CRWMS M&O 2001c) which was prepared in accordance with AP-2.21Q, ''Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities''; Attachment 4 of AP-ESH-008, ''Hazards Analysis System''; and AP-3.11Q, ''Technical Reports''. The objective of this report is to establish the requirements that provide for facility nuclear safety and a proper level of personnel safety and property protection from the effects of fire and the adverse effects of fire-extinguishing agents.

  18. Laryngeal electromyography in movement disorders: preliminary data

    Directory of Open Access Journals (Sweden)

    Kimaid Paulo A.T.

    2004-01-01

    Full Text Available This study describes preliminary laryngeal electromyography (LEMG data and botulinum toxin treatment in patients with dysphonia due to movement disorders. Twenty-five patients who had been clinically selected for botulinum toxin administration were examined, 19 with suspected laryngeal dystonia or spasmodic dysphonia (SD, 5 with vocal tremor, and 1 with Gilles de la Tourette syndrome (GTS. LEMG evaluations were performed before botulinum toxin administration using monopolar electrodes. Electromyography was consistent with dystonia in 14 patients and normal in 5, and differences in frequency suggesting essential tremor in 3 and Parkinson tremors in 2. The different LEMG patterns and significant improvement in our patients from botulinum toxin therapy has led us to perform laryngeal electromyography as a routine in UNICAMP movement disorders ambulatory.

  19. Building integrated photovoltaic systems analysis: Preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1993-08-01

    The National Renewable Energy Laboratory (NREL) has estimated that the deployment of photovoltaics (PV) in the commercial buildings sector has the potential to contribute as much as 40 gigawatts peak electrical generation capacity and displace up to 1.1 quads of primary fuel use. A significant portion of this potential exists for smaller buildings under 25,000 square feet (2,300 square meters) in size or two stories or less, providing a strong cross over potential for residential applications as well. To begin to achieve this potential, research is needed to define the appropriate match of PV systems to energy end-uses in the commercial building sector. This report presents preliminary findings for a technical assessment of several alternative paths to integrate PV with building energy systems.

  20. Preliminary Design of a Femtosecond Oscilloscope

    CERN Document Server

    Gazazyan, Edmond D; Kalantaryan, Davit K; Laziev, Edouard; Margaryan, Amour

    2005-01-01

    The calculations on motion of electrons in a finite length electromagnetic field of linearly and circularly polarized laser beams have shown that one can use the transversal deflection of electrons on a screen at a certain distance after the interaction region for the measurement of the length and longitudinal particle distribution of femtosecond bunches. In this work the construction and preliminary parameters of various parts of a device that may be called femtosecond oscilloscope are considered. The influence of various factors, such as the energy spread and size of the electron bunches, are taken into account. For CO2 laser intensity 1016 W/cm2 and field free drift length 1m the deflection is 5.3 and 0.06 cm, while the few centimeters long interaction length between 2 mirrors requires assembling accuracy 6 mm and 1.3 micron for 20 MeV to 50 keV, respectively.

  1. Warm pre-stressing, preliminary experiments

    International Nuclear Information System (INIS)

    Hedner, G.

    1984-09-01

    The beneficial effect of warm pre-stressing, WPS, on apparent fracture thoughness at low temperature is well established. Tests are usually performed with constant load during the cooling part of the load cycle. In practice load variations may occur during this part. The present paper reports a preliminary study of the influence of superimposed fatigue loads. It is found that if crack propagation occurs during cooling+fatigue loading, then the maximum load during the fatigue load cycle is the preload to be used for WPS consideration. A few tests were preformed to study the effect of preload reversal. Tensile preload was followed by a compressive load and after unloading the specimens were cooled and fractured. It was found that for the high preload level used in the tests, the beneficial effect of the tensile preload could be totally annihilated by the compressive preload. (author)

  2. Breakthrough Propulsion Physics Workshop Preliminary Results

    Science.gov (United States)

    Millis, Marc G.

    1997-01-01

    In August, 1997, a NASA workshop was held to assess the prospects emerging from physics that might lead to creating the ultimate breakthroughs in space transportation: propulsion that requires no propellant mass, attaining the maximum transit speeds physically possible, and breakthrough methods of energy production to power such devices. Because these propulsion goals are presumably far from fruition, a special emphasis was to identify affordable, near-term, and credible research that could make measurable progress toward these propulsion goals. Experiments and theories were discussed regarding the coupling of gravity and electromagnetism, vacuum fluctuation energy, warp drives and wormholes, and superluminal quantum tunneling. Preliminary results of this workshop are presented, along with the status of the Breakthrough Propulsion Physics program that conducted this workshop.

  3. Preliminary study of radium-contaminated soils

    International Nuclear Information System (INIS)

    Healy, J.W.; Rodgers, J.C.

    1978-10-01

    A preliminary study was made of the potential radiation exposures to people from radium-226 contamination in the soil in order to provide guidance on limits to be applied in decontaminating land. Pathways included were inhalation of radium from resuspension; ingestion of radium with foods; external gamma radiation from radium daughters; inhalation of radon and daughter, both in the open air and in houses; and the intake of 210 Pb and 210 Po from both inhalation and ingestion. The depth of the contaminated layer is of importance for external exposure and especially for radon emanation. The most limiting pathway was found to be emanation of the radon into buildings with limiting values comparable to those found naturally in many areas

  4. Preliminary engineering requirements on accelerators for ADS

    International Nuclear Information System (INIS)

    Giraud, B.; Cinotti, L.; Farrar, B.

    2001-01-01

    This paper describes the methodology adopted for the definition of accelerator reliability requirements and the preliminary results obtained by the European Industrial partnership involved in the development of an accelerator-driven subcritical system (ADS) demonstrator. The current feedback from the operation of high power accelerators exhibits a tendency toward a significant number of beam trips of varying duration. Thus, the number of shutdown transients is potentially significantly higher than for critical reactors. In order to specify reliability targets for accelerator development, the influence of a large number of beam trips on the structural integrity of ADS reactor subsystems (window/target, fuel, structures, components) has to be assessed. As far as the reactor structures are concerned, the analysis can be based on the large experience gained on structural mechanics for sodium-cooled critical fast breeder reactors (FBR) and extrapolated to both gas-cooled and liquid metal [sodium or lead-bismuth eutectic (LBE)] cooled ADS. (authors)

  5. Atomic Energy Control Board vocabulary - preliminary edition

    International Nuclear Information System (INIS)

    Nolet, D.

    1995-09-01

    This preliminary edition was prepared at the Board's request to help it establish a standardized terminology. It was produced by scanning the 99 French and English documents listed at the end of this Vocabulary. The documents include legislation concerning atomic energy and the transportation of radioactive materials, as well as the Board's publications, such as the Consultative Documents, Regulatory Documents and Notices. The terms included from the following areas are: radiation protection, reactor technology, nuclear fuel cycle, radioactive material packaging and transportation, radioactive waste management, uranium mines, and medical and industrial applications of radioelements. Also included are the titles of publications and the names of organizations and units. The vocabulary contains 2,589 concepts, sometimes accompanied by definitions, contexts or usage examples. Where terms have been standardized by the Canadian Committee for the Standardization of Nuclear Terminology, this has been indicated. Where possible, we have verified the terms using the TERMIUM, the Government of Canada Linguistic Data Bank. (author)

  6. EURISOL Multi-MW Target: Preliminary Study

    CERN Document Server

    A.Herrera-Martínez and Y.Kadi

    This technical note summarises the design calculations performed within Task #2 of the EURopean Isotope Separation On-Line Radioactive Ion Beam Facility Design Study (EURISOL DS).A preliminary study was carried out in order to determine the optimum value of relevant parameters in the target design. Different scenarios were simulated using the Monte Carlo code FLUKA. Namely, sensitivity studies were performed to assess the impact of the projectile particle energy on the neutronics and energy deposition in the spallation target. The optimum target dimension was also studied for every case as well as the proper target material for the liquid metal proton-to-neutron converter, since mercury and lead-bismuth eutectic are reasonable options. The effect of the beam width on the power densities was also evaluated, taking into account the geometrical limitations of the facility. Finally, a comparison between protons and deuterons as primary particles was performed, acknowledging the limitations of using FLUKA for thes...

  7. North Korean refugee doctors' preliminary examination scores

    Directory of Open Access Journals (Sweden)

    Sung Uk Chae

    2016-12-01

    Full Text Available Purpose Although there have been studies emphasizing the re-education of North Korean (NK doctors for post-unification of the Korean Peninsula, study on the content and scope of such re-education has yet to be conducted. Researchers intended to set the content and scope of re-education by a comparative analysis for the scores of the preliminary examination, which is comparable to the Korean Medical Licensing Examination (KMLE. Methods The scores of the first and second preliminary exams were analyzed by subject using the Wilcoxon signed rank test. The passing status of the group of NK doctors for KMLE in recent 3 years were investigated. The multiple-choice-question (MCQ items of which difficulty indexes of NK doctors were lower than those of South Korean (SK medical students by two times of the standard deviation of the scores of SK medical students were selected to investigate the relevant reasons. Results The average scores of nearly all subjects were improved in the second exam compared with the first exam. The passing rate of the group of NK doctors was 75%. The number of MCQ items of which difficulty indexes of NK doctors were lower than those of SK medical students was 51 (6.38%. NK doctors’ lack of understandings for Diagnostic Techniques and Procedures, Therapeutics, Prenatal Care, and Managed Care Programs was suggested as the possible reason. Conclusion The education of integrated courses focusing on Diagnostic Techniques and Procedures and Therapeutics, and apprenticeship-style training for clinical practice of core subjects are needed. Special lectures on the Preventive Medicine are likely to be required also.

  8. Preliminary dose assessment of the Chernobyl accident

    International Nuclear Information System (INIS)

    Hull, A.P.

    1987-01-01

    From the major accident at Unit 4 of the Chernobyl nuclear power station, a plume of airborne radioactive fission products was initially carried northwesterly toward Poland, thence toward Scandinavia and into Central Europe. Reports of the levels of radioactivity in a variety of media and of external radiation levels were collected in the Department of Energy's Emergency Operations Center and compiled into a data bank. Portions of these and other data which were obtained directly from published and official reports were utilized to make a preliminary assessment of the extent and magnitude of the external dose to individuals downwind from Chernobyl. Radioactive 131 I was the predominant fission product. The time of arrival of the plume and the maximum concentrations of 131 I in air, vegetation and milk and the maximum reported depositions and external radiation levels have been tabulated country by country. A large amount of the total activity in the release was apparently carried to a significant elevation. The data suggest that in areas where rainfall occurred, deposition levels were from ten to one-hundred times those observed in nearby ''dry'' locations. Sufficient spectral data were obtained to establish average release fractions and to establish a reference spectra of the other nuclides in the release. Preliminary calculations indicated that the collective dose equivalent to the population in Scandinavia and Central Europe during the first year after the Chernobyl accident would be about 8 x 10 6 person-rem. From the Soviet report, it appears that a first year population dose of about 2 x 10 7 person-rem (2 x 10 5 Sv) will be received by the population who were downwind of Chernobyl within the U.S.S.R. during the accident and its subsequent releases over the following week. 32 refs., 14 figs., 20 tabs

  9. A phenomenographic investigation into Information Literacy in nursing practice - preliminary findings and methodological issues.

    Science.gov (United States)

    Forster, Marc

    2013-10-01

    Information Literacy is essential to 'evidence-based practice'; without the ability to locate evidence, evidence-based practice is rendered extremely difficult if not impossible. There is currently little evidence to show how Information Literacy is experienced by nurses or what its parameters are within evidence-based practice and therefore whether Information Literacy educational interventions are actually promoting the correct knowledge and skills. Using phenomenographic interviews the author will attempt to discover how nurses experience Information Literacy. Insights from the findings will be used to map out its parameters and to put forward a theoretical model for a course or module to develop it effectively. This article presents preliminary findings, including 7 draft categories of description of how Information Literacy is experienced in nursing. This pilot study indicates that the complete findings may be of significant potential value in the promotion and development of Information Literacy education in nursing. It is argued that such insights into how nurses actually experience the phenomenon of Information Literacy can be used to develop potentially more effective, research-based, educational interventions. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Coordination in contractual relations: Some preliminary findings from the Malaysian housing industry

    Directory of Open Access Journals (Sweden)

    Suraya Ismail

    2008-12-01

    Full Text Available The traditional general procurement route found in many housing projects in Malaysia is conceptualized as a governance structure following the transaction cost economics (TCE approach. This approach has been used to examine governance structures in different economic sectors in several countries but evidence of its use in the context of developing countries is limited. This lack of evidence has prompted the authors to conduct a preliminary study to ascertain whether a TCE approach can explain construction governance structures in developing countries. This research does not discuss the trade-off that governs the choice of hybrids, market or hierarchies for organizing transactions. Rather, it takes advantage of existing research to substantiate the specific properties of hybrid organizations as governance structures. The main focus is coordination. Coordination is specified at two levels. At Level 1 is the coordination of specialization (i.e. the formation of the project team members and at Level 2 is the coordination mode of the contracting parties (client and contractor and the agents involved (the lead designer and project manage r. A case survey method was adopted. Preliminary findings seem to suggest that clients have used hierarchical themes in the contracts and high powered incentives to coordinate with in the contracting parties. The research findings suggest that all participants involved in the sample studied used governance structures symptomatic of a hybrid organization.

  11. Turning Evidence into Practice

    Science.gov (United States)

    CGH CRTA, Hillary Topazian, attended the National Cancer Institute’s 3rd Symposium on Global Cancer Research; a satellite meeting to the 6th Annual Consortium of Universities for Global Health (CUGH) Conference in Boston. The Symposium centered on the theme of implementation science, a field which studies the integration of research findings and evidence into healthcare policy and practice.

  12. Gait as evidence

    DEFF Research Database (Denmark)

    Lynnerup, Niels; Larsen, Peter Kastmand

    2014-01-01

    This study examines what in Denmark may constitute evidence based on forensic anthropological gait analyses, in the sense of pointing to a match (or not) between a perpetrator and a suspect, based on video and photographic imagery. Gait and anthropometric measures can be used when direct facial...

  13. What Counts as Evidence?

    Science.gov (United States)

    Dougherty Stahl, Katherine A.

    2014-01-01

    Each disciplinary community has its own criteria for determining what counts as evidence of knowledge in their academic field. The criteria influence the ways that a community's knowledge is created, communicated, and evaluated. Situating reading, writing, and language instruction within the content areas enables teachers to explicitly…

  14. Evidence in criminal procedure

    Directory of Open Access Journals (Sweden)

    Paolo Ferrua

    2018-03-01

    Full Text Available This paper analyzes the three components of the evidence operation: proof premises or evidence in the strict sense, with particular regard to the distinction between evidence declaration and critical/circumstantial evidence; the propositions to be proved, principal or incidental, final or intermediate; the act of proving, connoted by the rule of beyond all reasonable doubt. While the first two terms vary according to the procedural context, the third remains indefectible, since it is incongruous to consider any proposition to be 'proven' while there is a reasonable reason to doubt it. With regard to the distribution of the burden of proof, the structure of the case and its legal qualification, whether substantial or procedural, are decisive. Therefore, it is possible to identify, for each decision alternative, the term 'marked', which conveys the proposition to be proved, and the opposite 'consequential' term, which derives from the failure to reach the proof: for example, with respect to the main object in trial, the term 'marked' is the conviction, the term 'consequential' the acquittal.

  15. Evidence of Absence software

    Science.gov (United States)

    Dalthorp, Daniel; Huso, Manuela M. P.; Dail, David; Kenyon, Jessica

    2014-01-01

    Evidence of Absence software (EoA) is a user-friendly application used for estimating bird and bat fatalities at wind farms and designing search protocols. The software is particularly useful in addressing whether the number of fatalities has exceeded a given threshold and what search parameters are needed to give assurance that thresholds were not exceeded. The software is applicable even when zero carcasses have been found in searches. Depending on the effectiveness of the searches, such an absence of evidence of mortality may or may not be strong evidence that few fatalities occurred. Under a search protocol in which carcasses are detected with nearly 100 percent certainty, finding zero carcasses would be convincing evidence that overall mortality rate was near zero. By contrast, with a less effective search protocol with low probability of detecting a carcass, finding zero carcasses does not rule out the possibility that large numbers of animals were killed but not detected in the searches. EoA uses information about the search process and scavenging rates to estimate detection probabilities to determine a maximum credible number of fatalities, even when zero or few carcasses are observed.

  16. Implications of the LHCb Evidence for Charm CP Violation

    CERN Document Server

    Isidori, Gino; Ligeti, Zoltan; Perez, Gilad

    2012-01-01

    The LHCb collaboration recently announced preliminary evidence for CP violation in D meson decays. We discuss this result in the context of the standard model (SM), as well as its extensions. In the absence of reliable methods to evaluate the hadronic matrix elements involved, we can only estimate qualitatively the magnitude of the non-SM tree level operators required to generate the observed central value. In the context of an effective theory, we list the operators that can give rise to the measured CP violation and investigate constraints on them from other processes.

  17. Serological Evidence of Dengue Fever Among Refugees, Hargeysa, Somalia

    Science.gov (United States)

    1989-01-01

    AD-A24 1 179 Q O0T!119910 j •___ C PUBLICATION REPORT 1602 84/89-90 SEROLOGICAL EVIDENCE OF DENGUE FEVER AMONG REFUGEES, HARGEYOA, SOMALIA BY Boulos...of Dengue Fever Among Refugees, Hargeysa, Somalia Boulos A.M. Botros, Douglas M. Watts, Atef K. Soliman, Adel W. Salib, Mahmoud I. Moussa, H. Mursal...Tukei PM 1982). Epidemic Dengue fever caused by Dengue tion, antibody demonstrated by the EIA, IFA, and HI type-2 virus in Kenya: Preliminary results

  18. Evidence of circadian rhythms in non-photosynthetic bacteria?

    Directory of Open Access Journals (Sweden)

    Soriano María I

    2010-09-01

    Full Text Available Abstract Examples of circadian rhythms have been described in eukaryotic organisms and in photosynthetic bacteria, but direct proof of their existence in other prokaryotes is limited and has been largely ignored. The aim of this article is to review existing evidence and to present preliminary results that suggest that the heterotrophic bacterium Pseudomonas putida shows regular variations in its growth pattern synchronized with light/darkness cycles. We put forward the hypothesis that circadian regulation of certain processes can take place in non-photosynthetic prokaryotes and may represent an adaptative advantage in specific environments.

  19. Multiple Lines of Evidence

    Energy Technology Data Exchange (ETDEWEB)

    Amidan, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Venzin, Alexander M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bramer, Lisa M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-06-03

    This paper discusses the process of identifying factors that influence the contamination level of a given decision area and then determining the likelihood that the area remains unacceptable. This process is referred to as lines of evidence. These lines of evidence then serve as inputs for the stratified compliance sampling (SCS) method, which requires a decision area to be divided into strata based upon contamination expectations. This is done in order to focus sampling efforts more within stratum where contamination is more likely and to use the domain knowledge about these likelihoods of the stratum remaining unacceptable to buy down the number of samples necessary, if possible. Two different building scenarios were considered as an example (see Table 3.1). SME expertise was elicited concerning four lines of evidence factors (see Table 3.2): 1) amount of contamination that was seen before decontamination, 2) post-decontamination air sampling information, 3) the applied decontaminant information, and 4) the surface material. Statistical experimental design and logistic regression modelling were used to help determine the likelihood that example stratum remained unacceptable for a given example scenario. The number of samples necessary for clearance was calculated by applying the SCS method to the example scenario, using the estimated likelihood of each stratum remaining unacceptable as was determined using the lines of evidence approach. The commonly used simple random sampling (SRS) method was also used to calculate the number of samples necessary for clearance for comparison purposes. The lines of evidence with SCS approach resulted in a 19% to 43% reduction in total number of samples necessary for clearance (see Table 3.6). The reduction depended upon the building scenario, as well as the level of percent clean criteria. A sensitivity analysis was also performed showing how changing the estimated likelihoods of stratum remaining unacceptable affect the number

  20. NSLS-II Preliminary Design Report

    International Nuclear Information System (INIS)

    Dierker, S.

    2007-01-01

    Following the CD0 approval of the National Synchrotron Light Source II (NSLS-II) during August 2005, Brookhaven National Laboratory prepared a conceptual design for a worldclass user facility for scientific research using synchrotron radiation. DOE SC review of the preliminary baseline in December 2006 led to the subsequent CD1 approval (approval of alternative selection and cost range). This report is the documentation of the preliminary design work for the NSLS-II facility. The preliminary design of the Accelerator Systems (Part 1) was developed mostly based of the Conceptual Design Report, except for the Booster design, which was changed from in-storage-ring tunnel configuration to in external- tunnel configuration. The design of beamlines (Part 2) is based on designs developed by engineering firms in accordance with the specification provided by the Project. The conventional facility design (Part 3) is the Title 1 preliminary design by the AE firm that met the NSLS-II requirements. Last and very important, Part 4 documents the ES and H design and considerations related to this preliminary design. The NSLS-II performance goals are motivated by the recognition that major advances in many important technology problems will require scientific breakthroughs in developing new materials with advanced properties. Achieving this will require the development of new tools that will enable the characterization of the atomic and electronic structure, chemical composition, and magnetic properties of materials, at nanoscale resolution. These tools must be nondestructive, to image and characterize buried structures and interfaces, and they must operate in a wide range of temperatures and harsh environments. The NSLS-II facility will provide ultra high brightness and flux and exceptional beam stability. It will also provide advanced insertion devices, optics, detectors, and robotics, and a suite of scientific instruments designed to maximize the scientific output of the

  1. NSLS-II Preliminary Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Dierker, S.

    2007-11-01

    Following the CD0 approval of the National Synchrotron Light Source II (NSLS-II) during August 2005, Brookhaven National Laboratory prepared a conceptual design for a worldclass user facility for scientific research using synchrotron radiation. DOE SC review of the preliminary baseline in December 2006 led to the subsequent CD1 approval (approval of alternative selection and cost range). This report is the documentation of the preliminary design work for the NSLS-II facility. The preliminary design of the Accelerator Systems (Part 1) was developed mostly based of the Conceptual Design Report, except for the Booster design, which was changed from in-storage-ring tunnel configuration to in external- tunnel configuration. The design of beamlines (Part 2) is based on designs developed by engineering firms in accordance with the specification provided by the Project. The conventional facility design (Part 3) is the Title 1 preliminary design by the AE firm that met the NSLS-II requirements. Last and very important, Part 4 documents the ES&H design and considerations related to this preliminary design. The NSLS-II performance goals are motivated by the recognition that major advances in many important technology problems will require scientific breakthroughs in developing new materials with advanced properties. Achieving this will require the development of new tools that will enable the characterization of the atomic and electronic structure, chemical composition, and magnetic properties of materials, at nanoscale resolution. These tools must be nondestructive, to image and characterize buried structures and interfaces, and they must operate in a wide range of temperatures and harsh environments. The NSLS-II facility will provide ultra high brightness and flux and exceptional beam stability. It will also provide advanced insertion devices, optics, detectors, and robotics, and a suite of scientific instruments designed to maximize the scientific output of the facility

  2. Preliminary investigations of the thermal energy grid concept

    Energy Technology Data Exchange (ETDEWEB)

    Olszewski, M.

    1977-10-01

    This study examines, in a preliminary manner, the feasibility of the thermal grid concept. This concept essentially envisions the supply of heat to a long-distance transmission line from a dual-purpose nuclear or coal-fired power plant. The transmission line delivers heat to a subregion distribution network which delivers it to the consumer. District chilled water supply is also considered, using heat from the grid to power steam-turbine-driven water chillers. Candidate technologies for generation, transmission, and distribution of thermal energy are identified and assessed. Potential applications, including both industrial use and residential space conditioning and hot water supply, are evaluated. Results indicate that high-temperature hot-water transmission lines are favored for longer distances, while steam lines may be acceptable for shorter distances. It is also evident that thermal grid heat is more economically competitive for new applications, as opposed to retrofit situations, in the residential-commercial sector. The two applications are about equally feasible in the industrial sector. The results further indicate that thermal grid heat is most competitive in areas of high-heat-load density and expensive fuel costs. It appears that the thermal grid service area should include the industrial sector as a base load. The multifamily residential-commercial sector space and water heating loads can be added to the service area to maximize utilization of the transmission line and maintain low transmission costs. Supply of chilled water to the multifamily residential-commercial sector can also be included for new applications to increase the transmission line use factor. The thermal grid concept appears to be economically and technically feasible, when compared to oil and electric systems in the multifamily residential-commercial sector and coal- or oil-fired systems in the industrial sector, and should be explored in greater detail.

  3. Evidence on acne therapy

    Directory of Open Access Journals (Sweden)

    Caroline Sousa Costa

    Full Text Available Among the current treatments available for acne vulgaris, many widely practiced options lack support from studies at the best level of scientific evidence. The aim of this narrative review was to present the very latest information on topical and systemic treatments for acne vulgaris. Information from systematic reviews and well-designed clinical trials, obtained through a systematic search of the major medical databases, is emphasized. There are important issues regarding the clinical management of acne that still lack consistent grounding in scientific evidence. Among these are the optimum dose and duration of treatment with oral antibiotics that can be given without inducing bacterial resistance, and the safety of oral isotretinoin.

  4. Evidence informed decision making

    DEFF Research Database (Denmark)

    Sharma, Tarang; Choudhury, Moni; Kaur, Bindweep

    2015-01-01

    from the literature and a combined best practice checklist has been proposed. CONCLUSIONS: As decisions often need to be made in areas where there is a lack of published scientific evidence, CE is employed. Therefore to ensure its appropriateness the development of a validated CE data quality check......-list to assist decision makers is essential and further research in this area is a priority....

  5. Observational evidence for mergers

    International Nuclear Information System (INIS)

    Schweizer, F.

    1983-01-01

    Theory has long suggested that dynamical friction between colliding galaxies must lead to mergers. The problem for observers has been to find which galaxies are mergers. The author first reviews the available evidence for mergers in various kinds of galaxies, then proposes a tentative classification scheme for mergers, and finally discusses mergers in giant ellipticals and their relation to the evolution and perhaps even the formation of ellipticals. (Auth.)

  6. Preliminary ethical appraisal of a trial - what's it all about?

    Science.gov (United States)

    Siipi, Helena

    Preliminary ethical appraisal of medical trials is often based on the following four principles: respect for autonomy, beneficence, non-maleficence, and justice. Preliminary ethical appraisal should, however, not be understood solely as application of these four principles to practice. Ethical committees will inevitably interpret the principles and make decisions about their reciprocal importance in connection with each trial. Reasoning does not always proceed from above towards practical recommendations of action, but can instead also be based on a moral rule or practice relating to a certain action. A good preliminary ethical appraisal will also take into account everyday standards of morality, law and shared moral values of the society.

  7. Preliminary results of steel containment vessel model test

    International Nuclear Information System (INIS)

    Matsumoto, T.; Komine, K.; Arai, S.

    1997-01-01

    A high pressure test of a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of a steel containment vessel (SCV), representing an improved boiling water reactor (BWR) Mark II containment, was conducted on December 11-12, 1996 at Sandia National Laboratories. This paper describes the preliminary results of the high pressure test. In addition, the preliminary post-test measurement data and the preliminary comparison of test data with pretest analysis predictions are also presented

  8. The role of NASTRAN in the preliminary design cycle

    Science.gov (United States)

    Grooms, H. R.; Baipsys, V. J.

    1993-01-01

    This paper explains how NASTRAN can be utilized advantageously in the preliminary design cycle. The initial portion of the preliminary design process lends itself to programs that can produce multiple configurations or variations on a particular design with minimal cost or effort. The latter portion of the process encompasses refining the design and adding more detailed analyses (particularly for other disciplines). A method for quickly generating balanced spacecraft loading conditions for use in preliminary design and analysis also is explained. The following additional sections are included: Background, Symbols, Analytical Process, Aerodynamic Load Distributions, NASTRAN Applications, Conclusion and References.

  9. Case histories as evidence.

    Science.gov (United States)

    Herxheimer, Andrew; Healy, David; Menkes, David B

    2012-01-01

    In courts case histories play a central part when a crime may have resulted from an effect of a prescribed drug; in civil cases where a person may have suffered damage from a drug; and in coroners' enquiries into the cause of unexplained deaths. The court must decide two important questions: 1. Can the suspected medication(s) cause this kind of effect? 2. Did it (or they) do so in this particular case? Many judges and coroners have not addressed these questions clearly and have not used expert witnesses consistently, on occasion disregarding scientific evidence. Courts need to appoint experts to explain and interpret the scientific evidence. Few judges are equipped to resolve contradictions between different experts. Brief accounts of five cases from four countries illustrate these points. The reluctance of legal processes to implicate drugs as a possible cause of violent behaviour leads to injustice. Courts must be required to obtain appropriate expert evidence, and be given independent data on which drugs can cause such behaviour.

  10. Preliminary geological suitability assessment for LILW disposal

    International Nuclear Information System (INIS)

    Tomse, P.; Mele, I.

    2001-01-01

    Due to the growing need for a final disposal of LILW, the final solution for the short-lived LILW is the key issue of radioactive waste management in Slovenia at the moment. ARAO - the Slovenian Agency for Radwaste Management - is intensely involved in the re-initiated site selection process for a LILW repository. In this new process we are trying to combine as best as possible the technical, geologically-led and the advocacy-site selection processes. By a combination of technical and volunteer approach to the site selection we wish to guarantee high public involvement and sufficient flexibility of the process to adapt to specific conditions or new circumstances while the project is ongoing. In the technical phase, our tendency is to retain a larger number of potential areas/sites. We also keep open the possibility of choosing the type of repository. The decision between the surface and underground option will be made only once the site has been defined. In accordance with the IAEA recommendations the site selection process is divided into four stages: the conceptual and planning stage, area survey stage, site characterisation stage and site confirmation stage. Last year the area survey stage was started. In the preliminary geological suitability assessment the required natural predisposition of Slovene territory was assessed in order to locate geologically suitable formations. The assessment of natural conditions of the system was based on consideration of the main geological, hydro-geological and seismotectonic conditions. It was performed with ARC/INFO technology. The results are compiled in a map, showing potential areas for underground and surface disposal of LILW in Slovenia. It has been established that there is a potential suitability for both surface and underground disposal on about 10 000 km 2 of the Slovenian territory, which represents almost half of the entire Slovenian territory. These preliminary results are now being carefully re-examined. As an

  11. Preliminary Framework for Human-Automation Collaboration

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna Helene [Idaho National Lab. (INL), Idaho Falls, ID (United States); Le Blanc, Katya Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spielman, Zachary Alexander [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    The Department of Energy’s Advanced Reactor Technologies Program sponsors research, development and deployment activities through its Next Generation Nuclear Plant, Advanced Reactor Concepts, and Advanced Small Modular Reactor (aSMR) Programs to promote safety, technical, economical, and environmental advancements of innovative Generation IV nuclear energy technologies. The Human Automation Collaboration (HAC) Research Project is located under the aSMR Program, which identifies developing advanced instrumentation and controls and human-machine interfaces as one of four key research areas. It is expected that the new nuclear power plant designs will employ technology significantly more advanced than the analog systems in the existing reactor fleet as well as utilizing automation to a greater extent. Moving towards more advanced technology and more automation does not necessary imply more efficient and safer operation of the plant. Instead, a number of concerns about how these technologies will affect human performance and the overall safety of the plant need to be addressed. More specifically, it is important to investigate how the operator and the automation work as a team to ensure effective and safe plant operation, also known as the human-automation collaboration (HAC). The focus of the HAC research is to understand how various characteristics of automation (such as its reliability, processes, and modes) effect an operator’s use and awareness of plant conditions. In other words, the research team investigates how to best design the collaboration between the operators and the automated systems in a manner that has the greatest positive impact on overall plant performance and reliability. This report addresses the Department of Energy milestone M4AT-15IN2302054, Complete Preliminary Framework for Human-Automation Collaboration, by discussing the two phased development of a preliminary HAC framework. The framework developed in the first phase was used as the

  12. INADMISSIBLE EVIDENCE IN CIVIL PROCEDURE

    Directory of Open Access Journals (Sweden)

    Mihajlo Dika

    2016-01-01

    Full Text Available This paper examines the exclusion of specific means of evidence as instruments for determining the object of evidence, as well as the taking of evidence in the framework of the Croatian civil procedure law. The introduction lays the grounds for classifying and qualifying exclusion of evidence (general, special; absolute, relative; removable, irremovable; direct, indirect, after which greater attention is paid to the so called absolute and relative type; exclusionary evidence of the direct relative type pertaining to the establishing of facts, and evidence dismissals. With regard to the indirect relative type, the paper examines exclusionary evidence concerning the object of evidence. The remainder of the paper focuses on illegally obtained evidence, while outlining the constitutional, statutory, judicature and doctrinaire premises of bearing for such evidence. Subsequently, the question of evidence obtained in violation of the Constitutional guarantee of respect and legal protection of private and family life, dignity, reputation and honour, as well as evidence obtained by breach of the Constitutional guarantee of freedom and secrecy of correspondence and all other forms of communication, and in violation of the right to safety and privacy of personal data, are discussed too. In addition, the paper analyses the institutions of preclusion of evidence and the so called informative evidence. Concluding, the author points to a lacking regulation of inadmissible evidence within the Croatian civil procedure law, underlining the need to determine de lege ferenda legal requirements with a view to operationalizing inadmissible evidence within the Croatian civil procedure law.

  13. Case Grammar in Philippine Languages. Preliminary Draft.

    Science.gov (United States)

    Stevens, Alan M.

    This paper presents evidence from Philippine languages which suggests a number of modifications in the theory of case grammar. Philippine languages and adjacent related languages mark the case relationship between the verb and one noun phrase in the sentence by a particle on the noun phrase and an affix on the verb, a phenomenon which in recent…

  14. SMART core preliminary nuclear design-II

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Chan; Ji, Seong Kyun; Chang, Moon Hee

    1997-06-01

    Three loading patterns for 330 MWth SMART core are constructed for 25, 33 and 29 CRDMs, and one loading pattern for larger 69-FA core with 45 CRDMs is also constructed for comparison purpose. In this study, the core consists of 57 reduced height Korean Optimized Fuel Assemblies (KOFAs) developed by KAERI. The enrichment of fuel is 4.95 w/o. As a main burnable poison, 35% B-10 enriched B{sub 4}C-Al{sub 2}O{sub 3} shim is used. To control stuck rod worth, some gadolinia bearing fuel rods are used. The U-235 enrichment of the gadolinia bearing fuel rods is 1.8 w/o as used in KOFA. All patterns return cycle length of about 3 years. Three loading patterns except 25-CRDM pattern satisfy cold shutdown condition of keff {<=} 0.99 without soluble boron. These three patterns also satisfy the refueling condition of keff {<=} 0.95. In addition to the construction of loading pattern, an editing module of MASTER PPI files for rod power history generation is developed and rod power histories are generated for 29-CRDM loading pattern. Preliminary Fq design limit is suggested as 3.71 based on KOFA design experience. (author). 9 tabs., 45 figs., 16 refs.

  15. Preliminary studies of the biosynthesis of Austin

    International Nuclear Information System (INIS)

    Wicnienski, N.A.

    1979-01-01

    Aspergillus ustus is one of the most prevalent fungi in the soil. There are now two reports of the occurrence of toxin-producing strains of this fungus on stored foodstuffs. In addition, strains of A. ustus have been isolated along with Penicillium species from samples of South African cheeses. All A. ustus isolates tested were judged to be highly toxic to ducklings when grown on maize meal, however, the toxins involved were not isolated. Austin is the trivial name of one of the toxins made by the fungus found on stored food. Preliminary work to studying the biosynthesis of this compound using 13 C-labeled sodium acetate is reported here. The feasibility of the biosynthetic study was determined by feeding [1- 14 C]-sodium acetate to A. ustus cultures. The assignments made in the 13 C-nmr spectrum of Austin are shown. The lowest dilution factor obtained in [1- 14 C]-sodium acetate feeding experiments was 14. This dilution factor is sufficiently low to allow a successful feeding of [1,2- 13 C 2 ]-sodium acetate. A new metabolite of A. ustus, deacetylaustin, was isolated and identified. An alkaloid of unknown structure was also isolated from the fungus

  16. Cockpit task management: A preliminary, normative theory

    Science.gov (United States)

    Funk, Ken

    1991-01-01

    Cockpit task management (CTM) involves the initiation, monitoring, prioritizing, and allocation of resources to concurrent tasks as well as termination of multiple concurrent tasks. As aircrews have more tasks to attend to due to reduced crew sizes and the increased complexity of aircraft and the air transportation system, CTM will become a more critical factor in aviation safety. It is clear that many aviation accidents and incidents can be satisfactorily explained in terms of CTM errors, and it is likely that more accidents induced by poor CTM practice will occur in the future unless the issue is properly addressed. The first step in understanding and facilitating CTM behavior was the development of a preliminary, normative theory of CTM which identifies several important CTM functions. From this theory, some requirements for pilot-vehicle interfaces were developed which are believed to facilitate CTM. A prototype PVI was developed which improves CTM performance and currently, a research program is under way that is aimed at developing a better understanding of CTM and facilitating CTM performance through better equipment and procedures.

  17. Preliminary Slope Stability Study Using Slope/ W

    International Nuclear Information System (INIS)

    Nazran Harun; Mohd Abd Wahab Yusof; Kamarudin Samuding; Mohd Muzamil Mohd Hashim; Nurul Fairuz Diyana Bahrudin

    2014-01-01

    Analyzing the stability of earth structures is the oldest type of numerical analysis in geotechnical engineering. Limit equilibrium types of analyses for assessing the stability of earth slopes have been in use in geotechnical engineering for many decades. Modern limit equilibrium software is making it possible to handle ever-increasing complexity within an analysis. It is being considered as the potential method in dealing with complex stratigraphy, highly irregular pore-water pressure conditions, various linear and nonlinear shear strength models and almost any kind of slip surface shape. It allows rapid decision making by providing an early indication of the potential suitability of sites based on slope stability analysis. Hence, a preliminary slope stability study has been developed to improve the capacity of Malaysian Nuclear Agency (Nuclear Malaysia) in assessing potential sites for Borehole Disposal for Disused Sealed Radioactive Sources. The results showed that geometry of cross section A-A ' , B-B ' , C-C ' and D-D ' achieved the factor of safety not less than 1.4 and these are deemed acceptable. (author)

  18. PRELIMINARY SELECTION OF MGR DESIGN BASIS EVENTS

    International Nuclear Information System (INIS)

    Kappes, J.A.

    1999-01-01

    The purpose of this analysis is to identify the preliminary design basis events (DBEs) for consideration in the design of the Monitored Geologic Repository (MGR). For external events and natural phenomena (e.g., earthquake), the objective is to identify those initiating events that the MGR will be designed to withstand. Design criteria will ensure that radiological release scenarios resulting from these initiating events are beyond design basis (i.e., have a scenario frequency less than once per million years). For internal (i.e., human-induced and random equipment failures) events, the objective is to identify credible event sequences that result in bounding radiological releases. These sequences will be used to establish the design basis criteria for MGR structures, systems, and components (SSCs) design basis criteria in order to prevent or mitigate radiological releases. The safety strategy presented in this analysis for preventing or mitigating DBEs is based on the preclosure safety strategy outlined in ''Strategy to Mitigate Preclosure Offsite Exposure'' (CRWMS M andO 1998f). DBE analysis is necessary to provide feedback and requirements to the design process, and also to demonstrate compliance with proposed 10 CFR 63 (Dyer 1999b) requirements. DBE analysis is also required to identify and classify the SSCs that are important to safety (ITS)

  19. Preliminary Study of Fly Ash Ceramic Process

    International Nuclear Information System (INIS)

    Herry-Poernomo; Djoko-Sardjono, Ign.

    2000-01-01

    Preliminary study of ceramic production process from two components ofwhich are fly ash and feldspar has been done. Aluminosilicate substancecontained in the fly ash is a basic material a former ceramic body, if itfired at the temperature of 1000 o C forms mullite (3Al 2 O 3 .2SiO 2 ). Mulliteis a refractory material which is very stable at the temperature changing.This experiment studies the ceramic production process of two componentsnamely fly ash with particle size of o C.Steps of processes are making paste of fly ash and feldspar, making of greenpellets, and firing of pellets, physical analysis of ceramic including volumedecrease, lost ignition, porosity, density, water sorption, compressivestrength. The experiment result at firing temperature of 1000 o C were shownthat best composition at the weight ratio of fly ash to feldspar are 60/40and 50/50. It physical characteristic respectively are decrease of volume0.54 and 0.69 %, lost ignition = 11.98 and 11.78 %, porosity = 0.159 and0.155, density = 2.05 and 2.06 g/cm 3 , water sorption = 18.96 and 18.36 %,compressive strength = 24.82 and 24.79 kN/mm 2 . (author)

  20. The deuteron accelerator preliminary design for BISOL

    Energy Technology Data Exchange (ETDEWEB)

    Peng, S.X., E-mail: sxpeng@pku.edu.cn; Zhu, F.; Wang, Z.; Gao, Y.; Guo, Z.Y.

    2016-06-01

    BISOL, which was named as Beijing-ISOL before (Cui et al., 2013), is the abbreviation of Beijing Isotope-Separation-On-Line neutron beam facility. It is proposed jointly by Peking University (PKU) and China Institute of Atomic Energy (CIAE) for basic science study and application. It is a double driven facility that can be driven by a reactor or a deuteron accelerator. The deuteron driver accelerator should accelerate the deuteron beam up to 40 MeV with maximum beam current of 10 mA. Proton beams up to 33 MeV and He{sup 2+} beams up to 81.2 MeV can also be accelerated in this accelerator. The accelerator can be operated on either CW (continuous waveform) or pulsed mode, and the ion energy can be adjusted in a wide range. The accelerator will also allow independent operation of the RIB (Radioactive Ion Beams) system. It will be mainly charged by PKU group. Details of the deuteron accelerator preliminary design for BISOL will be given in this paper.

  1. Preliminary assessment of pump IST effectiveness

    International Nuclear Information System (INIS)

    DiBiasio, A.; Grove, E.; Carbonaro, J.

    1994-01-01

    A preliminary review of Inservice Testing (IST) effectiveness for Code Class 1, 2, and 3 pumps at nuclear power plants was performed. IST requirements are specified by ASME Section XI, and the Operations and Maintenance Standard (OM Part 6). The INPO NPRDS database was used to provide failure reports for these components for 1988 to 1992. This time frame coincides with the issuance of Generic Letter 89-04, which resulted in a more consistent application of the requirements by the licensees. For this time period, 2585 pump failures were reported. A review of these failures indicated that the majority (71.6%) were due to external leakage, and were excluded from this study since these events typically do not affect pump operability and are not detected by the measurement of IST parameters. Of the remaining 733 events, a review was performed to identify the primary failure causes, failure modes, and method of detection. Plant testing programs, consisting of IST, surveillance testing, and special testing, detected approximately 40% of these occurrences. Others were detected through operational abnormalities, routine and incidental observations, alarms, and while performing maintenance. This paper provides a discussion of the results of the study

  2. National uranium resource evaluation, preliminary report

    International Nuclear Information System (INIS)

    1976-06-01

    The results of the initial phase of the National Uranium Resource Evaluation (NURE) are reported. NURE is a comprehensive nationwide program to evaluate uranium resources and to identify areas favorable for uranium exploration. Part I presents estimates of uranium ore reserves and potential resources available at costs (not prices) of $10, $15, and $30 per pound U 3 O 8 (uranium oxide). These estimates comprise the national uranium resource position. They are, however, preliminary because limitations of time and available geologic data prevented adequate assessment of some areas that may be favorable for potential resources. Part II presents the potential uranium resources for each of 13 regions, whose boundaries have been drawn chiefly on geologic considerations. The general geology is summarized, and the types of uranium deposits are described. Although limited geologic reconnaissance was done in various parts of the country, the report is based primarily on the compilation and evaluation of data in ERDA files. Mining companies furnished a substantial amount of information on exploration results, development, production, and future plans. Published, manuscript, and open-file reports by government agencies, universities, and research organizations were reviewed. In addition, many individuals affiliated with universities and with state and federal agencies provided supplemental geologic information. This was particularly helpful in the eastern and central states and in Alaska, where information on uranium occurrences is limited

  3. Tritium oxidation and exchange: preliminary studies

    International Nuclear Information System (INIS)

    Phillips, J.E.; Easterly, C.E.

    1978-05-01

    The radiological hazard resulting from an exposure to either tritium oxide or tritium gas is discussed and the factors contributing to the hazard are presented. From the discussion it appears that an exposure to tritium oxide vapor is 10 4 to 10 5 times more hazardous than exposure to tritium gas. Present and future sources of tritium are briefly considered and indicate that most of the tritium has been and is being released as tritium oxide. The likelihood of gaseous releases, however, is expected to increase in the future, calling to task the present general release assumption that 100% of all tritium released is as oxide. Accurate evaluation of the hazards from a gaseous release will require a knowledge of the conversion rate of tritium gas to tritium oxide. An experiment for determining the conversion rate of tritium gas to tritium oxide is presented along with some preliminary data. The conversion rates obtained for low initial concentrations (10 -4 to 10 -1 mCi/ml) indicate the conversion may proceed more rapidly than would be expected from an extrapolation of previous data taken at higher concentrations

  4. Preliminary assessment of pump IST effectiveness

    International Nuclear Information System (INIS)

    DiBiasio, A.; Grove, E.; Carbonaro, J.

    1994-01-01

    A preliminary review of inservice testing (IST) effectiveness for Class 1, 2, and 3 pumps at nuclear power plants was performed. IST requirements are specified by the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code, Section XI, and the Operations and Maintenance Standard (OM Part 6). The Institute of Nuclear Power Operations Nuclear Plant Reliability Data System was used to provide failure reports for these components from 1988 to 1992. This time frame coincides with the issuance of Generic Letter 89-04, which resulted in a more consistent application of the requirements by the licensees. For this time, 2,585 pump failures were reported. A review of these failures indicated that the majority (71.6%) resulted from external leakage. These events were excluded from the study because the typically do not affect pump operability and are not detected by the measurement of IST parameters. The remaining 733 events were reviewed to identify the primary failure causes, failure modes, and method of detection. Plant testing programs, consisting of IST, surveillance testing, detected approximately 40% of these occurrences. Others were detected through operational abnormalities, routine and incidental observations, alarms, and while performing maintenance. This paper discusses the results of the study

  5. Guidance for performing preliminary assessments under CERCLA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-09-01

    EPA headquarters and a national site assessment workgroup produced this guidance for Regional, State, and contractor staff who manage or perform preliminary assessments (PAs). EPA has focused this guidance on the types of sites and site conditions most commonly encountered. The PA approach described in this guidance is generally applicable to a wide variety of sites. However, because of the variability among sites, the amount of information available, and the level of investigative effort required, it is not possible to provide guidance that is equally applicable to all sites. PA investigators should recognize this and be aware that variation from this guidance may be necessary for some sites, particularly for PAs performed at Federal facilities, PAs conducted under EPA`s Environmental Priorities Initiative (EPI), and PAs at sites that have previously been extensively investigated by EPA or others. The purpose of this guidance is to provide instructions for conducting a PA and reporting results. This guidance discusses the information required to evaluate a site and how to obtain it, how to score a site, and reporting requirements. This document also provides guidelines and instruction on PA evaluation, scoring, and the use of standard PA scoresheets. The overall goal of this guidance is to assist PA investigators in conducting high-quality assessments that result in correct site screening or further action recommendations on a nationally consistent basis.

  6. PRELIMINARY SELECTION OF MGR DESIGN BASIS EVENTS

    Energy Technology Data Exchange (ETDEWEB)

    J.A. Kappes

    1999-09-16

    The purpose of this analysis is to identify the preliminary design basis events (DBEs) for consideration in the design of the Monitored Geologic Repository (MGR). For external events and natural phenomena (e.g., earthquake), the objective is to identify those initiating events that the MGR will be designed to withstand. Design criteria will ensure that radiological release scenarios resulting from these initiating events are beyond design basis (i.e., have a scenario frequency less than once per million years). For internal (i.e., human-induced and random equipment failures) events, the objective is to identify credible event sequences that result in bounding radiological releases. These sequences will be used to establish the design basis criteria for MGR structures, systems, and components (SSCs) design basis criteria in order to prevent or mitigate radiological releases. The safety strategy presented in this analysis for preventing or mitigating DBEs is based on the preclosure safety strategy outlined in ''Strategy to Mitigate Preclosure Offsite Exposure'' (CRWMS M&O 1998f). DBE analysis is necessary to provide feedback and requirements to the design process, and also to demonstrate compliance with proposed 10 CFR 63 (Dyer 1999b) requirements. DBE analysis is also required to identify and classify the SSCs that are important to safety (ITS).

  7. Preliminary Assessment of a Compliant Gait Exoskeleton.

    Science.gov (United States)

    Cestari, Manuel; Sanz-Merodio, Daniel; Garcia, Elena

    2017-06-01

    Current commercial wearable gait exoskeletons contain joints with stiff actuators that cannot adapt to unpredictable environments. These actuators consume a significant amount of energy, and their stiffness may not be appropriate for safe human-machine interactions. Adjustable compliant actuators are being designed and implemented because of their ability to minimize large forces due to shocks, to safely interact with the user, and to store and release energy in passive elastic elements. Introduction of such compliant actuation in gait exoskeletons, however, has been limited by the larger power-to-weight and volume ratio requirement. This article presents a preliminary assessment of the first compliant exoskeleton for children. Compliant actuation systems developed by our research group were integrated into the ATLAS exoskeleton prototype. The resulting device is a compliant exoskeleton, the ATLAS-C prototype. The exoskeleton is coupled with a special standing frame to provide balance while allowing a semi-natural gait. Experiments show that when comparing the behavior of the joints under different stiffness conditions, the inherent compliance of the implemented actuators showed natural adaptability during the gait cycle and in regions of shock absorption. Torque tracking of the joint is achieved, identifying the areas of loading response. The implementation of a state machine in the control of knee motion allowed reutilization of the stored energy during deflection at the end of the support phase to partially propel the leg and achieve a more natural and free swing.

  8. Preliminary isodose calculation for gynecological curietherapy

    International Nuclear Information System (INIS)

    Bridier, A.; Dutreix, A.; Gerbaulet, A.; Chassagne, D.

    1981-01-01

    We present a preliminary method of calculating the dimensions of the reference isodose, based upon the geometrical distribution and length of the sources used, their linear activity and the length of treatment, that does not require use of a computer. Inversely, this method can be used to determine the factors necessary to produce a given shape of isodose, and also to predict the change in shape of the isodose that will be produced by altering the various factors. This method was derived from a systematic computer study of dose distribution in which each factor was varied independently of all others. The dimensions of the isodoses, calculated by this method, were found to be in agreement with those derived from computer calculation to within an error of about 2 mm. The method is only applicable for a limited range of positions of the vaginal sources. The influence of the positions of these sources along the line of the axis of uterine catheter and of their inclination to this line, are currently being studied. The results are presented as mathematical formulae relating each dimension of the isodose curves to the features of the application, but could equally well be expressed in tabular form that would be more convenient for everyday use. An example of the calculation used is given to facilitate understanding of the method [fr

  9. ALMA nutator design and preliminary performances

    Science.gov (United States)

    Martin-Cocher, Pierre; Ford, John; Koch, Patrick M.; Ni, Chih-Wen; Chen, Wei-Long; Chen, Ming-Tang; Raffin, Philippe; Ong, Ching-Long; Ho, Paul T. P.; Symmes, Arthur H.

    2012-09-01

    We report the past two years of collaboration between the different actors on the ALMA nutator. Building on previous developments, the nutator has seen changes in much of the design. A high-modulus carbon fiber structure has been added on the back of the mirror in order to transfer the voice coils forces with less deformation, thus reducing delay problems due to flexing. The controller is now an off-the-shelf National Instrument NI-cRIO, and the amplifier a class D servo drive from Advanced Motion Controls, with high peak power able to drive the coils at 300 Volts DC. The stow mechanism has been totally redesigned to improve on the repeatability and precision of the stow position, which is also the reference for the 26 bits Heidenhain encoders. This also improves on the accuracy of the stow position with wind loading. Finally, the software, written largely with National Instrument's LabView, has been developed. We will discuss these changes and the preliminary performance achieved to date.

  10. Preliminary assessment of valve IST effectiveness

    International Nuclear Information System (INIS)

    Grove, E.; DiBiasio, A.; Carbonaro, J.

    1994-01-01

    A preliminary review of inservice testing effectiveness for Code Class 1,2, and 3 valves at nuclear power plants was performed. These requirements are specified by the American Society of Mechanical Engineers Boiler and Pressure Vessel Code, Section XI, and the Operations and Maintenance Standard. The Institute of Nuclear Power Operations Nuclear Plant Reliability Data System (NPRDS) database was used to provide failure reports for these components for 1988 to 1992. This time period coincides with the issuance of Generic Letter 89-04, which resulted in a more consistent application of the requirements by the licensees. For this time period, 8,593 valve failures were identified. From the review of the NPRDS database, the primary failure causes and failure modes for motor-operated valves (MOV), air-operated valves (AOV), and check valves (CV) were identified. Solenoid-operated valves were not reviewed in this study. Plant testing programs were effective in identifying approximately 60% of the CV failures, 46% of the AOV failures, and 44% of the MOV failures

  11. Preliminary Test for Constitutive Models of CAP

    International Nuclear Information System (INIS)

    Choo, Yeon Joon; Hong, Soon Joon; Hwang, Su Hyun; Lee, Keo Hyung; Kim, Min Ki; Lee, Byung Chul; Ha, Sang Jun; Choi, Hoon

    2010-01-01

    The development project for the domestic design code was launched to be used for the safety and performance analysis of pressurized light water reactors. As a part of this project, CAP (Containment Analysis Package) code has been developing for the containment safety and performance analysis side by side with SPACE. The CAP code treats three fields (vapor, continuous liquid and dispersed drop) for the assessment of containment specific phenomena, and is featured by assessment capabilities in multi-dimensional and lumped parameter thermal hydraulic cell. Thermal hydraulics solver was developed and has a significant progress now. Implementation of the well proven constitutive models and correlations are essential in other for a containment code to be used with the generalized or optimized purposes. Generally, constitutive equations are composed of interfacial and wall transport models and correlations. These equations are included in the source terms of the governing field equations. In order to develop the best model and correlation package of the CAP code, various models currently used in major containment analysis codes, such as GOTHIC, CONTAIN2.0 and CONTEMPT-LT are reviewed. Several models and correlations were incorporated for the preliminary test of CAP's performance and test results and future plans to improve the level of execution besides will be discussed in this paper

  12. Preliminary Test for Constitutive Models of CAP

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Yeon Joon; Hong, Soon Joon; Hwang, Su Hyun; Lee, Keo Hyung; Kim, Min Ki; Lee, Byung Chul [FNC Tech., Seoul (Korea, Republic of); Ha, Sang Jun; Choi, Hoon [Korea Electric Power Research Institute, Daejeon (Korea, Republic of)

    2010-05-15

    The development project for the domestic design code was launched to be used for the safety and performance analysis of pressurized light water reactors. As a part of this project, CAP (Containment Analysis Package) code has been developing for the containment safety and performance analysis side by side with SPACE. The CAP code treats three fields (vapor, continuous liquid and dispersed drop) for the assessment of containment specific phenomena, and is featured by assessment capabilities in multi-dimensional and lumped parameter thermal hydraulic cell. Thermal hydraulics solver was developed and has a significant progress now. Implementation of the well proven constitutive models and correlations are essential in other for a containment code to be used with the generalized or optimized purposes. Generally, constitutive equations are composed of interfacial and wall transport models and correlations. These equations are included in the source terms of the governing field equations. In order to develop the best model and correlation package of the CAP code, various models currently used in major containment analysis codes, such as GOTHIC, CONTAIN2.0 and CONTEMPT-LT are reviewed. Several models and correlations were incorporated for the preliminary test of CAP's performance and test results and future plans to improve the level of execution besides will be discussed in this paper

  13. Preliminary studies on antibiotic-resistant Escherichia coli isolated ...

    African Journals Online (AJOL)

    Preliminary studies on antibiotic-resistant Escherichia coli isolated from cattle and children in the pastoral community of Nyabushozi, Uganda. J Okwee-Acai, S Majalija, SG Okech, MBS Kisaka, J Acon ...

  14. Preliminary safety information document for the standard MHTGR: Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    None

    1986-01-01

    This report presents preliminary safety information for the standard MHTGR. Topics discussed include: plant protection, instrumentation, and control; electrical systems; service systems; and steam and energy conversion systems. (JDB)

  15. Enhanced Preliminary Assessment Report: Jefferson Proving Ground Madison, Indiana

    National Research Council Canada - National Science Library

    Williamson, S; Ehrman, C; Venkateswar, R

    1990-01-01

    An enhanced preliminary assessment of Jefferson Proving Ground was performed to characterize the environmental impacts of actions occurring at the property, and to provide a basis for the development of remedial actions...

  16. Standing the Test of Time: Reference for a Preliminary Ruling

    DEFF Research Database (Denmark)

    Butler, Graham

    2017-01-01

    It is often too easy to forget just how important the preliminary reference procedure is for the functionality of European Union law. For the Court of Justice, there are both formal and informal means of judicial dialogue. This article focuses on the formal means of dialogue through the preliminary...... reference procedure that is available to all national courts throughout the Union. This contribution underlines how critical the system of preliminary references has been for both Union law, and national law, ensuring legal certainty and conformity across a diverse range of legal cultures. Accordingly......, it reflects on the true value the preliminary reference system, and highlights its continued importance for the development of both national and Union law....

  17. Preliminary observations on enemies of stingless bees and ...

    African Journals Online (AJOL)

    Preliminary observations on enemies of stingless bees and honeybee (Apis Mellifera adansonii L.) Colonies from the Miticivanga- Tshibinda sector east of Kahuzi Biega National Park, South-Kivu Province, eastern DR Congo.

  18. NOS CO-OPS Water Level Data, Preliminary, 1-Minute

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has recent, preliminary (not quality-controlled), 1-minute, water level (tide) data from NOAA NOS Center for Operational Oceanographic Products and...

  19. NOS CO-OPS Water Level Data, Preliminary, 6-Minute

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has recent, preliminary (not quality-controlled), 6-minute, water level (tide) data from NOAA NOS Center for Operational Oceanographic Products and...

  20. A preliminary survey of the genus Buchwaldoboletus (Boletales: Boletaceae)

    Science.gov (United States)

    Beatriz Ortiz-Santana; Ernst E. Both

    2011-01-01

    Buchwaldoboletus is a small genus of about a dozen species with a world-wide distribution. The boletes of this genus are non-mycorrhizal, saprophytic and lignicolous. A preliminary survey is provided and seven new combinations are proposed.

  1. Scope and purpose of the preliminary planning work

    International Nuclear Information System (INIS)

    Kalas, P.

    1976-01-01

    The results of preliminary planning work are usually expressed in a number of recommendations covering mainly: long-term national policy in the field of energy resources and selection of projects to be further studied at the feasibility level. Moreover, recommendations on further actions are made including: inventory of generation and transmission facilities recommended for the implementation in order to meet the load forecasted for medium-term period, preparation of a preliminary calender of decisions to be taken for the implementation of the projects recommended, preparation of a preliminary construction schedule, preparation of a preliminary investment program, preparation of a program of necessary engineering works, and performance of study on electricity rates which would adjust existing tariffs to proposed development program of the utility. (HP) [de

  2. Preliminary design report for the NAC combined transport cask

    International Nuclear Information System (INIS)

    1990-04-01

    Nuclear Assurance Corporation (NAC) is under contract to the United States Department of Energy (DOE) to design, license, develop and test models, and fabricate a prototype cask transportation system for nuclear spent fuel. The design of this combined transport (rail/barge) transportation system has been divided into two phases, a preliminary design phase and a final design phase. This Preliminary Design Package (PDP) describes the NAC Combined Transport Cask (NAC-CTC), the results of work completed during the preliminary design phase and identifies the additional detailed analyses, which will be performed during final design. Preliminary analytical results are presented in the appropriate sections and supplemented by summaries of procedures and assumptions for performing the additional detailed analyses of the final design. 60 refs., 1 fig., 2 tabs

  3. A preliminary assessment of the palate and tongue for detecting ...

    African Journals Online (AJOL)

    A preliminary assessment of the palate and tongue for detecting organophosphorus and carbamate pesticide exposure in the degraded carcasses of vultures and other animals. Ngaio L Richards, Irene Zorilla, Isabel Fernandez, Monica Calvino, Joaquin Garcia, Antonio Ruiz ...

  4. Preliminary In Vivo Experiments on Adhesion of Geckos

    OpenAIRE

    Lepore, E.; Brianza, S.; Antoniolli, F.; Buono, M.; Carpinteri, A.; Pugno, N.

    2008-01-01

    We performed preliminary experiments on the adhesion of a Tokay gecko on surfaces with different roughness, with or without particles with significant different granulometry, before/after or during the moult. The results were analyzed using the Weibull statistics.

  5. Evidence-based librarianship: searching for the needed EBL evidence.

    Science.gov (United States)

    Eldredge, J D

    2000-01-01

    This paper discusses the challenges of finding evidence needed to implement Evidence-Based Librarianship (EBL). Focusing first on database coverage for three health sciences librarianship journals, the article examines the information contents of different databases. Strategies are needed to search for relevant evidence in the library literature via these databases, and the problems associated with searching the grey literature of librarianship. Database coverage, plausible search strategies, and the grey literature of library science all pose challenges to finding the needed research evidence for practicing EBL. Health sciences librarians need to ensure that systems are designed that can track and provide access to needed research evidence to support Evidence-Based Librarianship (EBL).

  6. Limitations of Expert Evidence

    OpenAIRE

    Serpil Salaçin

    1997-01-01

    Limitations of Expert Evidence Edited by Stephen Leadbeatter MB ChB MCRPath ISBN 1 86016 029 8 Printed in Great Britain by Cathedral Print Services Ltd, Salisbury, 1996 Kitap 25 Ekim 1994 te The Royal College of Physicians ve The Royal College of Pathologists tarafından düzenlenen konferanstan sonra hekimlere ve avukatlara konuyu tartışmaya açmak için basılmış. Bilirkişi görüşünün temel filozofisinin, bu görevi yapanlar ve bu hizmeti alanların yapabileceklerin...

  7. PRELIMINARY PHYTOCHEMICAL AND HISTOCHEMICAL INVESTIGATION ON KIGELIA PINNATA DC.,

    OpenAIRE

    DHANASEKARAN.M; ABRAHAM.G.C; MOHAN.S

    2014-01-01

    Kigelia pinnata D.C. the mid sized ornamental tree of the Bignoniaceae has been studied by preliminary phytochemical and histochemical analysis. Several local names are availability to this plants based on their country. They are called worsboom in Africa and sauage tree in America. The tree is 25 meters in hight with a dense rounded crown bark grey. Data gathered on solvent extraction and preliminary phytochemical method suggested that the presence of glycosides, flavonoides, tannin and alka...

  8. TITAN Legal Weight Truck cask preliminary design report

    International Nuclear Information System (INIS)

    1990-04-01

    The Preliminary Design of the TITAN Legal Weight Truck (LWT) Cask System and Ancillary Equipment is presented in this document. The scope of this document includes the LWT cask with fuel baskets, impact limiters, and lifting and tiedown features; the cask support system for transportation; intermodal transfer skid; personnel barrier; and cask lifting yoke assembly. The results of the tradeoff studies and evaluations that were performed during the preliminary design are presented in Appendix A to this report. 51 figs., 17 tabs

  9. Magnetic resonance imaging of the brain in neonates. Preliminary results

    International Nuclear Information System (INIS)

    Dumoulin, M.; Legrand, M.; Gremillet, C.; Lecouffe, P.; Rousseau, J.; Pruvo, J.P.; Marchandise, X.

    1991-01-01

    The place of neonatal cerebral MRI and its specific contribution compared with conventional imaging techniques were evaluated in 36 patients. The difficulties specific to the patient population studied met during this preliminary period are described, with their local solutions. A preliminary evaluation of the diagnostic and prognostic value of MRI according to the disease state and gestational age is presented. The specific contribution of MRI compared with transfontanellar ultrasonography and CT scan is discussed [fr

  10. Evidence from the Cochrane Collaboration for Traditional Chinese Medicine Therapies

    Science.gov (United States)

    Wieland, Susan; Kimbrough, Elizabeth; Cheng, Ker; Berman, Brian M.

    2009-01-01

    Abstract Background The Cochrane Collaboration, an international not-for-profit organization that prepares and maintains systematic reviews of randomized trials of health care therapies, has produced reviews summarizing much of the evidence on Traditional Chinese Medicine (TCM). Our objective was to review the evidence base according to Cochrane systematic reviews. Methods In order to detect reviews focusing on TCM, we searched the titles and abstracts of all reviews in Issue 4, 2008 of the Cochrane Database of Systematic Reviews. For each review, we extracted data on the number of trials included and the total number of participants. We provided an indication of the strength of the review findings by assessing the reviewers' abstract conclusions statement. We supplemented our assessment of the abstract conclusions statements with a listing of the comparisons and outcomes showing statistically significant meta-analyses results. Results We identified 70 Cochrane systematic reviews of TCM, primarily acupuncture (n = 26) and Chinese herbal medicine (n = 42), and 1 each of moxibustion and t'ai chi. Nineteen (19) of 26 acupuncture reviews and 22/42 herbal medicine reviews concluded that there was not enough good quality trial evidence to make any conclusion about the efficacy of the evaluated treatment, while the remaining 7 acupuncture and 20 herbal medicine reviews and each of the moxibustion and t'ai chi reviews indicated a suggestion of benefit, which was qualified by a caveat about the poor quality and quantity of studies. Most reviews included many distinct interventions, controls, outcomes, and populations, and a large number of different comparisons were made, each with a distinct forest plot. Conclusions Most Cochrane systematic reviews of TCM are inconclusive, due specifically to the poor methodology and heterogeneity of the studies reviewed. Some systematic reviews provide preliminary evidence of Chinese medicine's benefits to certain patient populations

  11. Evidence for homosexuality gene

    Energy Technology Data Exchange (ETDEWEB)

    Pool, R.

    1993-07-16

    A genetic analysis of 40 pairs of homosexual brothers has uncovered a region on the X chromosome that appears to contain a gene or genes for homosexuality. When analyzing the pedigrees of homosexual males, the researcheres found evidence that the trait has a higher likelihood of being passed through maternal genes. This led them to search the X chromosome for genes predisposing to homosexuality. The researchers examined the X chromosomes of pairs of homosexual brothers for regions of DNA that most or all had in common. Of the 40 sets of brothers, 33 shared a set of five markers in the q28 region of the long arm of the X chromosome. The linkage has a LOD score of 4.0, which translates into a 99.5% certainty that there is a gene or genes in this area that predispose males to homosexuality. The chief researcher warns, however, that this one site cannot explain all instances of homosexuality, since there were some cases where the trait seemed to be passed paternally. And even among those brothers where there was no evidence that the trait was passed paternally, seven sets of brothers did not share the Xq28 markers. It seems likely that homosexuality arises from a variety of causes.

  12. Preliminary design of the repository. Stage 2

    International Nuclear Information System (INIS)

    Saanio, T.; Kirkkomaeki, T.; Keto, P.; Kukkola, T.; Raiko, H.

    2007-04-01

    Spent nuclear fuel from Finnish nuclear power plants will be disposed of in deep bedrock in Olkiluoto, Eurajoki. The repository is planned to be excavated at a depth of 400 - 500 metres. Access routes to the repository include a 1:10 inclined access tunnel, and vertical shafts. The fuel is encapsulated in the encapsulation plant above ground and transferred to the repository in the canister lift. Deposition tunnels, central tunnels and technical rooms are excavated at the disposal level. The canisters are deposited in deposition holes that are covered with bentonite blocks. The deposition holes are bored in the floors of the deposition tunnels. The central tunnel system consists of two parallel central tunnels that are inter-connected at certain distances. Two parallel central tunnels improve the fire safety of the rooms and also allow flexible backfilling and closing of the deposition tunnels in stages at the operational phase of the repository. An underground rock characterization facility, ONKALO, is excavated at the disposal level to support and confirm investigations carried out from above ground. ONKALO is designed so that it can later serve as part of the repository. ONKALO excavations were started in 2004. The repository will be excavated in the 2010s and operation will start in 2020. The fifth nuclear power unit makes the operational phase of the repository very long. Parts of the repository will be excavated and closed over the long operational period. The repository can be constructed at one or several levels. The one-storey alternative is the so-called reference alternative in this preliminary design report. The two-storey alternative is also taken into account in the ONKALO designs. The preliminary designs of the repository are presented as located in Olkiluoto. The location of the repository will be revised when more information on the bedrock has been gained. More detailed data of the circumstances will be obtained from above ground investigations

  13. Preliminary Evaluation of a New Cosmology Curriculum

    Science.gov (United States)

    Coble, Kimberly A.; Martin, Dominique; Hayes, Patrycia; Targett, Tom; Bailey, Janelle M.; Cominsky, Lynn R.

    2015-01-01

    Informed by our research on student understanding of cosmology, The Big Ideas in Cosmology is an immersive set of web-based learning modules that integrates text, figures, and visualizations with short and long interactive tasks and real cosmological data. This enables the transformation of general education astronomy and cosmology classes from primarily lecture and book-based courses to a more engaging format that builds important STEM skills.During the spring 2014 semester, we field-tested a subset of chapters with the general education astronomy and cosmology classes at Sonoma State University in a flipped-classroom format. We administered pre and post content and attitude assessments in the two flipped classes as well as two lecture classes. The majority of cosmology students had taken astronomy before whereas the astronomy students had not.When switching to an active mode of learning (e.g., flipped classroom instead of lecture), many instructors report pushback from students. We saw this effect from students in course evaluations, who reported dissatisfaction with "having to do more work." However, the students in the flipped section in astronomy made greater gains on the multiple choice content assessment than the students in either of the two lecture sections. On the attitude assessment (the CLASS), the cosmology students made a small shift toward more expert-like opinions. Preliminary results from open-ended content surveys indicate that, prior to instruction, students had difficulty answering 'why' or 'how do we know' questions; that post-instruction, students are less likely to respond "I don't know" or to leave an answer blank; and that students using the modules made gains in their content knowledge.Module development was supported by NASA ROSES E/PO Grant #NNXl0AC89G, the Illinois Space Grant Consortium, the Fermi E/PO program, Sonoma State University's Space Science Education and Public Outreach Group, and Great River Technology

  14. Preliminary safety analysis of the Gorleben site

    International Nuclear Information System (INIS)

    Bracke, G.; Fischer-Appelt, K.

    2014-01-01

    The safety requirements governing the final disposal of heat-generating radioactive waste in Germany were implemented by the Federal Ministry of Environment, Natural Conservation and Nuclear Safety (BMU) in 2010. The Ministry considers as a fundamental objective the protection of man and the environment against the hazards of radioactive waste. Unreasonable burdens and obligation for future generations shall be avoided. The main safety principles are concentration and inclusion of radioactive and other pollutants in a containment-providing rock zone. Any release of radioactive nuclides may increase the risk for men and the environment only negligibly compared to natural radiation exposure. No intervention or maintenance work shall be necessary in the post-closure phase. Retrieval/recovery of the waste shall be possible up to 500 years after closure. The Gorleben salt dome has been discussed since the 1970's as a possible repository site for heat-generating radioactive waste in Germany. The objective of the project preliminary safety analysis of the Gorleben site (VSG) was to assess if repository concepts at the Gorleben site or other sites with a comparable geology could comply with these requirements based on currently available knowledge (Fischer-Appelt, 2013; Bracke, 2013). In addition to this it was assessed if methodological approaches can be used for a future site selection procedure and which technological and conceptual considerations can be transferred to other geological situations. The objective included the compilation and review of the available exploration data of the Gorleben site and on disposal in salt rock, the development of repository designs, and the identification of the needs for future R and D work and further site investigations. (authors)

  15. Global Geologic Mapping of Io: Preliminary Results

    Science.gov (United States)

    Williams, David A.; Keszthelyi, L. P.; Crown, D. A.; Geissler, P. E.; Schenk, P. M.; Yff, Jessica; Jaeger, W. L.; Rathbun, J. A.

    2008-01-01

    A new global geologic map of Jupiter's volcanic moon, Io is being prepared, with the focus being on completion of a draft map by July 2008. Here initial results of the mapping are reported: a preliminary distribution of material units in terms of areas and a visual representation. Additionally, the mapping hopes to address some of the problems in Io geology. Thus far it has been discovered that Io's surface is dominated by plains material, thought to consist of Io's silicate crust covered by pyroclastic deposits and lava flows of silicate and sulfur-bearing composition. Many plains areas contain flow fields that cannot be mapped separately due to a lack of resolution or modification by alteration processes. Discrete lava flows and flow fields are the next most abundant unit, with bright (sulfur?) flows in greater abundance than dark (silicate?) flows. The source of most of Io's heat flow, the paterae, are the least abundant unit in terms of areal extent.Upon completion of the draft map for peer review, it will be used to investigate several specific questions about the geological evolution of Io that previously could not be well addressed, including: comparison of the areas versus the heights of Ionian mountains to assess their stability and evolution; correlation and comparison of Galileo Near-Infrared Mapping Spectrometer and Photopolarimeter-Radiometer hot spot locations with the mapped location of dark versus bright lava flows and patera floors to assess any variations in the types of sources for Io's active volcanism; and the creation of a global inventory of the areal coverage of dark and bright laval flows to assess the relative importance of sulfur versus silicate volcanism in resurfacing Io, and to assess whether there are regional concentrations of either style of volcanism that may have implications on interior processes.

  16. Preliminary experimental studies of waste coal gasification

    Energy Technology Data Exchange (ETDEWEB)

    Su, S.; Jin, Y.G.; Yu, X.X.; Worrall, R. [CSIRO, Brisbane, QLD (Australia). Advanced Coal Technology

    2013-07-01

    Coal mining is one of Australia's most important industries. It was estimated that coal washery rejects from black coal mining was approximately 1.82 billion tonnes from 1960 to 2009 in Australia, and is projected to produce another one billion tonnes by 2018 at the current production rate. To ensure sustainability of the Australian coal industry, we have explored a new potential pathway to create value from the coal waste through production of liquid fuels or power generation using produced syngas from waste coal gasification. Consequently, environmental and community impacts of the solid waste could be minimized. However, the development of an effective waste coal gasification process is a key to the new pathway. An Australian mine site with a large reserve of waste coal was selected for the study, where raw waste coal samples including coarse rejects and tailings were collected. After investigating the initial raw waste coal samples, float/sink testing was conducted to achieve a desired ash target for laboratory-scale steam gasification testing and performance evaluation. The preliminary gasification test results show that carbon conversions of waste coal gradually increase as the reaction proceeds, which indicates that waste coal can be gasified by a steam gasification process. However, the carbon conversion rates are relatively low, only reaching to 20-30%. Furthermore, the reactivity of waste coal samples with a variety of ash contents under N{sub 2}/air atmosphere have been studied by a home-made thermogravimetric analysis (TGA) apparatus that can make the sample reach the reaction temperature instantly.

  17. Metacognitions about smoking: a preliminary investigation.

    Science.gov (United States)

    Nikčević, Ana V; Spada, Marcantonio M

    2010-01-01

    Preliminary research has indicated that metacognitions are involved in smoking. In the present study, we aimed to investigate whether specific facets of metacognition play a role in explaining smoking initiation and perseveration. Twelve individuals, self-identified as regular smokers and scoring a positive value on the Fagerström Test of Nicotine Dependence, were assessed using a semi-structured interview to investigate the following: (1) whether they held positive and/or negative metacognitive beliefs about smoking; (2) what their main goal in smoking was, and how they knew if they had achieved their goal; (3) how they directed their focus of attention when smoking; and (4) what they perceived the advantages and disadvantages of these attentional strategies to be. Results indicated that participants endorsed both positive and negative metacognitive beliefs about smoking and that the goal of smoking was to regulate negative emotion and/or to enhance cognitive functioning. Participants reported that they relied either on an internal signal, such as improvement in the emotional/cognitive state, or on a physical sign, in the form of a finished cigarette, to determine if they had achieved their goal. During an episode of smoking, half of the participants reported focusing their attention internally on thoughts and feelings or the sensations of smoking. The remainder of participants reported either an exclusively external focus of attention (e.g., the environment) or a varied focus of attention. Most participants were able to identify advantages to their attentional strategies, whereas two reported perceived disadvantages. The implications of the findings are discussed.

  18. Preliminary design of a universal Martian lander

    Science.gov (United States)

    Norman, Timothy L.; Gaskin, David E.; Adkins, Sean; Gunawan, Mary; Johnson, Raquel; Macdonnell, David; Parlock, Andrew; Sarick, John; Bodwell, Charles; Hashimoto, Kouichi

    In the next 25 years, mankind will be undertaking yet another giant leap forward in the exploration of the solar system: a manned mission to Mars. This journey will provide important information on the composition and history of both Mars and the Solar System. A manned mission will also provide the opportunity to study how humans can adapt to long term space flight conditions and the Martian environment. As part of the NASA/USRA program, nineteen West Virginia University students conducted a preliminary design of a manned Universal Martian Lander (UML). The UML's design will provide a 'universal' platform, consisting of four modules for living and laboratory experiments and a liquid-fuel propelled Manned Ascent Return Vehicle (MARV). The distinguishing feature of the UML is the 'universal' design of the modules which can be connected to form a network of laboratories and living quarters for future missions thereby reducing development and production costs. The WVU design considers descent to Mars from polar orbit, a six month surface stay, and ascent for rendezvous. The design begins with an unmanned UML landing at Elysium Mons followed by the manned UML landing nearby. During the six month surface stay, the eight modules will be assembled to form a Martian base where scientific experiments will be performed. The mission will also incorporate hydroponic plant growth into a Controlled Ecological Life Support System (CELSS) for water recycling, food production, and to counteract psychological effects of living on Mars. In situ fuel production for the MARV will be produced from gases in the Martian atmosphere. Following surface operations, the eight member crew will use the MARV to return to the Martian Transfer Vehicle (MTV) for the journey home to Earth.

  19. Analytical Chemistry Core Capability Assessment - Preliminary Report

    International Nuclear Information System (INIS)

    Barr, Mary E.; Farish, Thomas J.

    2012-01-01

    The concept of 'core capability' can be nebulous one. Even at a fairly specific level, where core capability equals maintaining essential services, it is highly dependent upon the perspective of the requestor. Samples are submitted to analytical services because the requesters do not have the capability to conduct adequate analyses themselves. Some requests are for general chemical information in support of R and D, process control, or process improvement. Many analyses, however, are part of a product certification package and must comply with higher-level customer quality assurance requirements. So which services are essential to that customer - just those for product certification? Does the customer also (indirectly) need services that support process control and improvement? And what is the timeframe? Capability is often expressed in terms of the currently utilized procedures, and most programmatic customers can only plan a few years out, at best. But should core capability consider the long term where new technologies, aging facilities, and personnel replacements must be considered? These questions, and a multitude of others, explain why attempts to gain long-term consensus on the definition of core capability have consistently failed. This preliminary report will not try to define core capability for any specific program or set of programs. Instead, it will try to address the underlying concerns that drive the desire to determine core capability. Essentially, programmatic customers want to be able to call upon analytical chemistry services to provide all the assays they need, and they don't want to pay for analytical chemistry services they don't currently use (or use infrequently). This report will focus on explaining how the current analytical capabilities and methods evolved to serve a variety of needs with a focus on why some analytes have multiple analytical techniques, and what determines the infrastructure for these analyses. This information will be

  20. Methodology for Preliminary Design of Electrical Microgrids

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Richard P. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Stamp, Jason E. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Eddy, John P. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Henry, Jordan M [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Munoz-Ramos, Karina [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Abdallah, Tarek [U.S. Army Corps of Engineers, Washington, DC (United States)

    2015-09-30

    Many critical loads rely on simple backup generation to provide electricity in the event of a power outage. An Energy Surety Microgrid TM can protect against outages caused by single generator failures to improve reliability. An ESM will also provide a host of other benefits, including integration of renewable energy, fuel optimization, and maximizing the value of energy storage. The ESM concept includes a categorization for microgrid value proposi- tions, and quantifies how the investment can be justified during either grid-connected or utility outage conditions. In contrast with many approaches, the ESM approach explic- itly sets requirements based on unlikely extreme conditions, including the need to protect against determined cyber adversaries. During the United States (US) Department of Defense (DOD)/Department of Energy (DOE) Smart Power Infrastructure Demonstration for Energy Reliability and Security (SPIDERS) effort, the ESM methodology was successfully used to develop the preliminary designs, which direct supported the contracting, construction, and testing for three military bases. Acknowledgements Sandia National Laboratories and the SPIDERS technical team would like to acknowledge the following for help in the project: * Mike Hightower, who has been the key driving force for Energy Surety Microgrids * Juan Torres and Abbas Akhil, who developed the concept of microgrids for military installations * Merrill Smith, U.S. Department of Energy SPIDERS Program Manager * Ross Roley and Rich Trundy from U.S. Pacific Command * Bill Waugaman and Bill Beary from U.S. Northern Command * Melanie Johnson and Harold Sanborn of the U.S. Army Corps of Engineers Construc- tion Engineering Research Laboratory * Experts from the National Renewable Energy Laboratory, Idaho National Laboratory, Oak Ridge National Laboratory, and Pacific Northwest National Laboratory

  1. Preliminary classification criteria for the cryoglobulinaemic vasculitis

    Science.gov (United States)

    De Vita, S; Soldano, F; Isola, M; Monti, G; Gabrielli, A; Tzioufas, A; Ferri, C; Ferraccioli, G F; Quartuccio, L; Corazza, L; De Marchi, G; Casals, M Ramos; Voulgarelis, M; Lenzi, M; Saccardo, F; Fraticelli, P; Mascia, M T; Sansonno, D; Cacoub, P; Tomsic, M; Tavoni, A; Pietrogrande, M; Zignego, A L; Scarpato, S; Mazzaro, C; Pioltelli, P; Steinfeld, S; Lamprecht, P; Bombardieri, S; Galli, M

    2011-01-01

    Background To develop preliminary classification criteria for the cryoglobulinaemic syndrome or cryoglobulinaemic vasculitis (CV). Methods Study part I developed a questionnaire for CV to be included in the formal, second part (study part II). Positivity of serum cryoglobulins was defined by experts as an essential condition for CV classification. In study part II, a core set of classification items (questionnaire, clinical and laboratory items, as agreed) was tested in three groups of patients and controls—that is, group A (new patients with the CV), group B (controls with serum cryoglobulins but lacking CV) and group C (controls without serum cryoglobulins but with features which can be observed in CV). Results In study part I (188 cases, 284 controls), a positive response to at least two of three selected questions showed a sensitivity of 81.9% and a specificity of 83.5% for CV. This questionnaire was employed and validated in study part II, which included 272 patients in group A and 228 controls in group B. The final classification criteria for CV, by pooling data from group A and group B, required the positivity of questionnaire plus clinical, questionnaire plus laboratory, or clinical plus laboratory items, or all the three, providing a sensitivity of 88.5% and a specificity of 93.6% for CV. By comparing data in group A versus group C (425 controls), the same classification criteria showed a sensitivity 88.5% and a specificity 97.0% for CV. Conclusion Classification criteria for CV were developed, and now need validation. PMID:21571735

  2. Analytical Chemistry Core Capability Assessment - Preliminary Report

    Energy Technology Data Exchange (ETDEWEB)

    Barr, Mary E. [Los Alamos National Laboratory; Farish, Thomas J. [Los Alamos National Laboratory

    2012-05-16

    The concept of 'core capability' can be nebulous one. Even at a fairly specific level, where core capability equals maintaining essential services, it is highly dependent upon the perspective of the requestor. Samples are submitted to analytical services because the requesters do not have the capability to conduct adequate analyses themselves. Some requests are for general chemical information in support of R and D, process control, or process improvement. Many analyses, however, are part of a product certification package and must comply with higher-level customer quality assurance requirements. So which services are essential to that customer - just those for product certification? Does the customer also (indirectly) need services that support process control and improvement? And what is the timeframe? Capability is often expressed in terms of the currently utilized procedures, and most programmatic customers can only plan a few years out, at best. But should core capability consider the long term where new technologies, aging facilities, and personnel replacements must be considered? These questions, and a multitude of others, explain why attempts to gain long-term consensus on the definition of core capability have consistently failed. This preliminary report will not try to define core capability for any specific program or set of programs. Instead, it will try to address the underlying concerns that drive the desire to determine core capability. Essentially, programmatic customers want to be able to call upon analytical chemistry services to provide all the assays they need, and they don't want to pay for analytical chemistry services they don't currently use (or use infrequently). This report will focus on explaining how the current analytical capabilities and methods evolved to serve a variety of needs with a focus on why some analytes have multiple analytical techniques, and what determines the infrastructure for these analyses. This

  3. Preliminary hazard analysis using sequence tree method

    International Nuclear Information System (INIS)

    Huang Huiwen; Shih Chunkuan; Hung Hungchih; Chen Minghuei; Yih Swu; Lin Jiinming

    2007-01-01

    A system level PHA using sequence tree method was developed to perform Safety Related digital I and C system SSA. The conventional PHA is a brainstorming session among experts on various portions of the system to identify hazards through discussions. However, this conventional PHA is not a systematic technique, the analysis results strongly depend on the experts' subjective opinions. The analysis quality cannot be appropriately controlled. Thereby, this research developed a system level sequence tree based PHA, which can clarify the relationship among the major digital I and C systems. Two major phases are included in this sequence tree based technique. The first phase uses a table to analyze each event in SAR Chapter 15 for a specific safety related I and C system, such as RPS. The second phase uses sequence tree to recognize what I and C systems are involved in the event, how the safety related systems work, and how the backup systems can be activated to mitigate the consequence if the primary safety systems fail. In the sequence tree, the defense-in-depth echelons, including Control echelon, Reactor trip echelon, ESFAS echelon, and Indication and display echelon, are arranged to construct the sequence tree structure. All the related I and C systems, include digital system and the analog back-up systems are allocated in their specific echelon. By this system centric sequence tree based analysis, not only preliminary hazard can be identified systematically, the vulnerability of the nuclear power plant can also be recognized. Therefore, an effective simplified D3 evaluation can be performed as well. (author)

  4. Sample size and power determination when limited preliminary information is available

    Directory of Open Access Journals (Sweden)

    Christine E. McLaren

    2017-04-01

    Full Text Available Abstract Background We describe a novel strategy for power and sample size determination developed for studies utilizing investigational technologies with limited available preliminary data, specifically of imaging biomarkers. We evaluated diffuse optical spectroscopic imaging (DOSI, an experimental noninvasive imaging technique that may be capable of assessing changes in mammographic density. Because there is significant evidence that tamoxifen treatment is more effective at reducing breast cancer risk when accompanied by a reduction of breast density, we designed a study to assess the changes from baseline in DOSI imaging biomarkers that may reflect fluctuations in breast density in premenopausal women receiving tamoxifen. Method While preliminary data demonstrate that DOSI is sensitive to mammographic density in women about to receive neoadjuvant chemotherapy for breast cancer, there is no information on DOSI in tamoxifen treatment. Since the relationship between magnetic resonance imaging (MRI and DOSI has been established in previous studies, we developed a statistical simulation approach utilizing information from an investigation of MRI assessment of breast density in 16 women before and after treatment with tamoxifen to estimate the changes in DOSI biomarkers due to tamoxifen. Results Three sets of 10,000 pairs of MRI breast density data with correlation coefficients of 0.5, 0.8 and 0.9 were simulated and generated and were used to simulate and generate a corresponding 5,000,000 pairs of DOSI values representing water, ctHHB, and lipid. Minimum sample sizes needed per group for specified clinically-relevant effect sizes were obtained. Conclusion The simulation techniques we describe can be applied in studies of other experimental technologies to obtain the important preliminary data to inform the power and sample size calculations.

  5. Evidence for robots.

    Science.gov (United States)

    Shenoy, Ravikiran; Nathwani, Dinesh

    2017-01-01

    Robots have been successfully used in commercial industry and have enabled humans to perform tasks which are repetitive, dangerous and requiring extreme force. Their role has evolved and now includes many aspects of surgery to improve safety and precision. Orthopaedic surgery is largely performed on bones which are rigid immobile structures which can easily be performed by robots with great precision. Robots have been designed for use in orthopaedic surgery including joint arthroplasty and spine surgery. Experimental studies have been published evaluating the role of robots in arthroscopy and trauma surgery. In this article, we will review the incorporation of robots in orthopaedic surgery looking into the evidence in their use. © The Authors, published by EDP Sciences, 2017.

  6. Evidence on Inclusion

    DEFF Research Database (Denmark)

    Dyssegaard, Camilla Brørup; Larsen, Michael Søgaard

    The purpose of this publication is to examine existing research on inclusion to identify strategies of inclusion that have generated positive effects. To do so it is necessary to understand the effect of the applied strategies. One approach, which is being discussed, is to use evidence to determine...... which methods have proven more effective than others. The desire to gain insight into research on inclusion forms the basis of the current systematic review. The task was to determine which strategies primary research has found to be most effective for inclusion purposes. We have solved this task...... by addressing the existing research with the following question: What is the effect of including children with special needs in mainstream teaching in basic school, and which of the applied educational methods have proved to have a positive effect?...

  7. Expert opinion vs. empirical evidence

    Science.gov (United States)

    Herman, Rod A; Raybould, Alan

    2014-01-01

    Expert opinion is often sought by government regulatory agencies when there is insufficient empirical evidence to judge the safety implications of a course of action. However, it can be reckless to continue following expert opinion when a preponderance of evidence is amassed that conflicts with this opinion. Factual evidence should always trump opinion in prioritizing the information that is used to guide regulatory policy. Evidence-based medicine has seen a dramatic upturn in recent years spurred by examples where evidence indicated that certain treatments recommended by expert opinions increased death rates. We suggest that scientific evidence should also take priority over expert opinion in the regulation of genetically modified crops (GM). Examples of regulatory data requirements that are not justified based on the mass of evidence are described, and it is suggested that expertise in risk assessment should guide evidence-based regulation of GM crops. PMID:24637724

  8. Preliminary data from a randomized pilot study of web-based functional analytic psychotherapy therapist training.

    Science.gov (United States)

    Kanter, Jonathan W; Tsai, Mavis; Holman, Gareth; Koerner, Kelly

    2013-06-01

    Therapists of many persuasions emphasize the therapy relationship in their work, a priority backed by strong empirical evidence. Training in how to maximize the power and potential of the therapy relationship, however, has lagged behind. A novel approach to using the therapy relationship and to training therapists in its use is provided by Functional Analytic Psychotherapy (FAP). FAP training involves eight 2-hr weekly training sessions conducted online using web-conferencing technology. The training integrates behavioral principles with a focus on trainee-trainer and trainee-trainee relationships in a highly structured course that evokes the desirable FAP therapist-trainee behaviors and collectively shapes the behaviors through reinforcement by the trainer and other trainees. In a preliminary study, 16 therapist-trainees were randomly assigned to receive either immediate FAP training or training after a waitlist period. Significant and large effects of training were found on both self-reported and observer-assessed measures for the first training group, and the waitlist training group replicated the first training group with significant within-subject change over the course of training. Finally, qualitative feedback from therapists indicated high satisfaction with the primary elements of the training protocol. Several important limitations to this preliminary study are discussed.

  9. A preliminary investigation of stimulus control training for worry: effects on anxiety and insomnia.

    Science.gov (United States)

    McGowan, Sarah Kate; Behar, Evelyn

    2013-01-01

    For individuals with generalized anxiety disorder, worry becomes associated with numerous aspects of life (e.g., time of day, specific stimuli, environmental cues) and is thus under poor discriminative stimulus control (SC). In addition, excessive worry is associated with anxiety, depressed mood, and sleep difficulties. This investigation sought to provide preliminary evidence for the efficacy of SC procedures in reducing anxiety-, mood-, and sleep-related symptoms. A total of 53 participants with high trait worry were randomly assigned to receive 2 weeks of either SC training (consisting of a 30-min time- and place-restricted worry period each day) or a control condition called focused worry (FW; consisting of instructions to not avoid naturally occurring worry so that worry and anxiety would not paradoxically increase). At post-training, SC was superior to FW in producing reductions on measures of worry, anxiety, negative affect, and insomnia, but not on measures of depression or positive affect. Moreover, SC was superior to FW in producing clinically significant change on measures of worry and anxiety. Results provide preliminary support for the use of SC training techniques in larger treatment packages for individuals who experience high levels of worry.

  10. Stable isotope variations in benthic primary producers along the Bosphorus (Turkey): A preliminary study

    International Nuclear Information System (INIS)

    Calizza, Edoardo; Aktan, Yelda; Costantini, Maria Letizia; Rossi, Loreto

    2015-01-01

    Highlights: • Nitrogen pollution along the Bosphorus Strait was investigated. • C and N isotopic and elemental analyses on benthic primary producers were performed. • δ 15 N decreased, while δ 13 C and N% increased from north to south along the Strait. • Ulva lactuca was more useful than epiphytes as indicator of nitrogen pollution. • Preliminary isotopic analyses on resident organisms are useful monitoring tools. - Abstract: The Bosphorus Strait is a dynamic and complex system. Recent evidences showed nitrogen and heavy metal concentrations to follow opposite patterns across the Strait, suggesting a complex spatial organisation of the anthropogenic disturbance in this system. Here, we provide isotopic information on the origin and transportation of dissolved nitrogen along the Bosphorus. C and N isotopic and elemental analyses were performed on specimens of Ulva lactuca and associated epiphytes sampled in five locations across the Strait. Variations in C and N isotopic signatures were observed in U. lactuca, pointing to a decrease in the availability of anthropogenic organic dissolved nitrogen along a north-south direction. Conversely, epiphytes did not show isotopic or elemental patterns across the Strait. These results suggest that preliminary stable isotope surveys in extended costal systems basing on U. lactuca can represent a valuable tool to focus meaningful targets and hypotheses for pollution studies in the Mediterranean region

  11. Impact of abnormal cerebrovascular reactivity on BOLD fMRI: a preliminary investigation of moyamoya disease.

    Science.gov (United States)

    Mazerolle, Erin L; Ma, Yuhan; Sinclair, David; Pike, G Bruce

    2018-01-01

    Blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) studies of patients with cerebrovascular disease have largely ignored the confounds associated with abnormal cerebral blood flow, vascular reactivity and neurovascular coupling. We studied BOLD fMRI activation and cerebrovascular reactivity in moyamoya disease. To characterize the impact of remote vascular demands on BOLD fMRI measurements, we varied the vascular territories engaged by manipulating the experimental task performed by the participants. Vascular territories affected by disease were identified using BOLD cerebrovascular reactivity. Preliminary evidence from two patients pre- and postrevascularization surgery and four controls indicates that neurovascular coupling in affected brain regions can be modulated by the task-related vascular demands in unaffected regions. In one patient studied, we observed that brain regions with improved cerebrovascular reactivity after surgery demonstrated normalized neurovascular coupling, that is the degree to which neurovascular coupling was modulated by task-related vascular demands was decreased. We propose that variations in task-dependent neurovascular coupling in patients with moyamoya disease are likely related to vascular steal. While preliminary, our findings are a proof of concept of the limitations of BOLD fMRI in cerebrovascular disease and suggest a role for assessment of cerebrovascular reactivity to improve interpretation of task-related BOLD fMRI activation. © 2016 The Authors. Clinical Physiology and Functional Imaging published by John Wiley & Sons Ltd on behalf of Scandinavian Society of Clinical Physiology and Nuclear Medicine.

  12. Proposed preliminary definition of the disturbed-zone boundary appropriate for a repository at Yucca Mountain

    International Nuclear Information System (INIS)

    Langkopf, B.S.

    1987-12-01

    Some of the calculations that support the licensing of a repository for high-level radioactive waste will use the regulatory concept of a disturbed zone. The Nevada Nuclear Waste Storage Investigations (NNWSI) project must determine the location of the boundary of the disturbed zone for use in these calculations. This paper summarizes results of computer analyses and laboratory experiments and suggests a preliminary definition for the boundary of the disturbed zone for the unsaturated environment at Yucca Mountain. Although the intent of this paper is to define the boundary of the disturbed zone at the edge of significant changes in intrinsic hydrologic properties, there is no evidence of changes in intrinsic hydrologic properties that could significantly change the groundwater travel time from the repository to the water table. Such a result suggests that the disturbed zone at Yucca Mountain is of minimal extent. Because the analyses and experiments reviewed here indicate that there are a variety of changes near the waste package and because the results are subject to uncertainty, the preliminary suggestion for the extent of the disturbed zone is a value larger than the results themselves would suggest: the boundary is proposed to be a plane 10 m below the lower boundary of the waste packages. 88 refs., 12 figs., 5 tabs

  13. The Adolescent HIV Disclosure Cognition and Affect Scale: Preliminary Reliability and Validity.

    Science.gov (United States)

    Evangeli, Michael

    2017-07-01

    Globally, there are 2 million HIV-positive 10-19-year-olds. One challenge for this population is sharing their HIV status with others (onward HIV disclosure). There are no multi-item, multidimensional scales of HIV disclosure cognitions and affect for young people living with HIV. An 18-item measure of HIV disclosure cognition and affect was developed, administered to 65 adolescents living with HIV (aged 12-16 years). Data were explored using principal component analysis and preliminary construct and criterion validity assessed. Three factors were revealed: negative disclosure attitudes and feelings, self-efficacy, and positive disclosure attitudes and feelings. The full scale and its subscales were internally consistent. The total score showed statistically significant positive relationships with HIV disclosure in the past 6 months, HIV disclosure intention and self-perception. Preliminary evidence of the measure's good psychometric properties suggests it may be helpful in future clinical and research work. © The Author 2017. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  14. Helminthiases in Montes Claros. Preliminary survey

    Directory of Open Access Journals (Sweden)

    Rina Girard Kaminsky

    1976-04-01

    Full Text Available A preliminary survey was conducted for the presence of helminths in the city of Montes Claros, M. G., Brazil. Three groups of persons were examined by the direct smear, Kato thick film and MIFC techniques; one group by direct smear and Kato only. General findings were: a high prevalence of hookworm, followed by ascariasis, S. mansoni, S. stercoralis and very light infections with T. trichiurá. E. vermicularis and H. nana were ranking parasites at an orphanage, with some hookworm and S. mansoni infections as well. At a pig slaughter house, the dominant parasites were hookworm and S. mansoni. Pig cysticercosis was an incidental finding worth mentioning for the health hazard it represents for humans as well as an economic loss. From the comparative results between the Kato and the MIF the former proved itself again as a more sensitive and reliable concentration method for helminth eggs, of low cost and easy performance.Um estudo preliminar sobre helmintos foi feito na cidade de Montes Claros, MG, Brasil. Três grupos de pessoas foram examinados pelos métodos direto, de Kato e do MIF e um grupo pelos métodos direto e Kato exclusivamente. Encontrou-se uma alta prevalência de necatorose, seguindo-se ascaríase, S. mansoni, S. stercoralis, e infecções leves pelo T. trichiura. E. vermicularis e H. nana foram osparasitos mais prevalentes num orfanato, com alguns casos de infecção pelo Necator e S. mansoni. Cisticercose dos suinos foi achado incidental e é importante ser mencionada devido ao perigo que representa no plano da Saúde Pública, bem como pela perda econômica que produz. Discutiu-se brevemente a importância do solo na transmissão dos helmintos num clima quente e seco. Da comparação dos métodos de Kato e MIF, o primeiro demonstrou ser o método mais sensível para ovos de helmintos, de baixo custo e fácil preparo.

  15. Integrated Global Nuclear Materials Management Preliminary Concepts

    International Nuclear Information System (INIS)

    Jones, E; Dreicer, M.

    2006-01-01

    The world is at a turning point, moving away from the Cold War nuclear legacy towards a future global nuclear enterprise; and this presents a transformational challenge for nuclear materials management. Achieving safety and security during this transition is complicated by the diversified spectrum of threat 'players' that has greatly impacted nonproliferation, counterterrorism, and homeland security requirements. Rogue states and non-state actors no longer need self-contained national nuclear expertise, materials, and equipment due to availability from various sources in the nuclear market, thereby reducing the time, effort and cost for acquiring a nuclear weapon (i.e., manifestations of latency). The terrorist threat has changed the nature of military and national security requirements to protect these materials. An Integrated Global Nuclear Materials Management (IGNMM) approach would address the existing legacy nuclear materials and the evolution towards a nuclear energy future, while strengthening a regime to prevent nuclear weapon proliferation. In this paper, some preliminary concepts and studies of IGNMM will be presented. A systematic analysis of nuclear materials, activities, and controls can lead to a tractable, integrated global nuclear materials management architecture that can help remediate the past and manage the future. A systems approach is best suited to achieve multi-dimensional and interdependent solutions, including comprehensive, end-to-end capabilities; coordinated diverse elements for enhanced functionality with economy; and translation of goals/objectives or standards into locally optimized solutions. A risk-informed basis is excellent for evaluating system alternatives and performances, and it is especially appropriate for the security arena. Risk management strategies--such as defense-in-depth, diversity, and control quality--help to weave together various technologies and practices into a strong and robust security fabric. Effective

  16. First fungal genome sequence from Africa: A preliminary analysis

    Directory of Open Access Journals (Sweden)

    Rene Sutherland

    2012-01-01

    Full Text Available Some of the most significant breakthroughs in the biological sciences this century will emerge from the development of next generation sequencing technologies. The ease of availability of DNA sequence made possible through these new technologies has given researchers opportunities to study organisms in a manner that was not possible with Sanger sequencing. Scientists will, therefore, need to embrace genomics, as well as develop and nurture the human capacity to sequence genomes and utilise the ’tsunami‘ of data that emerge from genome sequencing. In response to these challenges, we sequenced the genome of Fusarium circinatum, a fungal pathogen of pine that causes pitch canker, a disease of great concern to the South African forestry industry. The sequencing work was conducted in South Africa, making F. circinatum the first eukaryotic organism for which the complete genome has been sequenced locally. Here we report on the process that was followed to sequence, assemble and perform a preliminary characterisation of the genome. Furthermore, details of the computer annotation and manual curation of this genome are presented. The F. circinatum genome was found to be nearly 44 million bases in size, which is similar to that of four other Fusarium genomes that have been sequenced elsewhere. The genome contains just over 15 000 open reading frames, which is less than that of the related species, Fusarium oxysporum, but more than that for Fusarium verticillioides. Amongst the various putative gene clusters identified in F. circinatum, those encoding the secondary metabolites fumosin and fusarin appeared to harbour evidence of gene translocation. It is anticipated that similar comparisons of other loci will provide insights into the genetic basis for pathogenicity of the pitch canker pathogen. Perhaps more importantly, this project has engaged a relatively large group of scientists

  17. Preliminary study of volcano monitoring using geochemical composition of lichen

    Science.gov (United States)

    KUAN, S.

    2012-12-01

    Taipei City, the capital of Taiwan, is bounded with Tatun Volcano Group (TVG), which is not active since 200 ka. However, some evidences indicate that the latest explosion of volcanic ash was dated to 5-6 ka as well as TVG is so close to metropolis. The monitoring on TVG is crucial for crisis management. For monitoring TVG, changes of geochemical signal in some volcanic gases and hot springs are currently assessed by monthly sampling. The geochemistry of volcanic gas and hot spring represents a short-term condition on sampling time and is highly controlled by temperature and precipitation on the surface. A long-term average geochemistry will be very helpful to be compared with the results of volcanic gas and hot spring. A bioindicator not only has the ability to store geochemical compositions in their tissues but also has a wide geographical distribution. It is very suitable in this kind of study and lichen is one of the best bioindicators mainly because lichens grow slowly and have a large-scale dependence upon the environment for their nutrition, In TVG, the high SO2 content in the atmosphere results in the absence of fruticose lichen. On the contrary, crustos lichen is the most common species in the study area. For the preliminary analysis, one fruticose, four foliose and four crustos lichens were collected around the major emission centers of volcanic gas. According to the results of ICP-MS analysis, the abundances of heavy metals are generally in the order of Zn, Fe, Mn, Cu, Cr, Pb, Cd, Ni, V, Co and U. Factor analysis (FA) demonstrates that most of the metals show very high loadings in the first factor. This means that the fractionation of metals among different lichen species is minor and the geochemical compositions of lichen are possibly controlled by the same source (atmosphere). The second factor of FA includes Mn, Sr and Ba, which share the same oxidation state of +2 in acidic environment. This factor can describe the variation of Mn, Sr and Ba in the

  18. Attachment and Aggressive Manifestations in Younger Adulthood - "Preliminary Findings"

    Directory of Open Access Journals (Sweden)

    Tatiana Lorincová

    2014-07-01

    Full Text Available The main topic of the contribution was comparison between retrospective attachment (emocional warmth and rejection and aggressive manifestations (physical aggressivness, verbal aggressivness, anger and hostility among younger adulthood. Bowlby's theory of attachment was that once a core attachment style develops in an infant, it will influence and shape the nature of all intimate relations for the individual moving forward throughout the infant's life cycle. Authors Mikulincer and Shaver (2011 explain how these primary attachment experiences would affect future emotional, cognitive and behavioral processes. Secure adolescents, in comparison to insecure ones are perceived as being less aggressive. Research has pointed out that secure parental attachment promotes adaptive psychological functioning. The direct relationship between attachment security and aggressive/delinquent behaviour is in line with prior evidence that secure adolescents rate higher in terms of emotional and social adjustment, enjoy more positive relationships with their family and peers, and are less likely to engage in externalizing problems, such as antisocial and aggressive behaviours. On the other hand, insecure attachment is connected with aggressive and externalizing behaviour. Hypotheses were formulated on the base of theoretical background and our assumption was, that younger adults with emocional warmth attachment will have lower level of aggressive manifestations (physical aggression, verbal aggression, anger and hostility than younger adults with rejectional attachment. We used two standardized questionnaires for data collection, s.E.M.B.U. Questionnaire, which measured retrospective attachment (emocional warmth and rejection and Questionnaire of Aggressivness, which measured aggressive manifestations. We used statistical analysis and we found statistically significant differencies, which are preliminary findings from broader research, between emocional warmth

  19. A preliminary study on titanium-clay interactions

    International Nuclear Information System (INIS)

    Wersin, P.; Grolimund, D.; Kumpulainen, S.; Brendle, J.; Snellman, M.

    2010-01-01

    bentonite, Opalinus Clay, Illite du Puy) were characterized by XAS. Preliminary results can be summarized as: (1) Natural clay materials contain significant but variable amounts of Ti. The standard purification procedure for bentonites to remove accessories does not or only barely removes Ti. (2) The Ti in the natural clays materials Rokle bentonite, Opalinus Clay, Illite du Puy occurs as microcrystalline TiO 2 (presumably as anatase). On the other hand, the Ti spectra in MX-80 suggest the presence of structural Ti in the smectite, but the evidence is not conclusive so far. (3) The exposure of purified MX-80 to titanium powder at room temperature within a period of five months did not lead to measurable additional Ti in the clay. This was even true for samples exposed to acidic or alkaline conditions where corrosion rates and solubility of Ti are known to be higher. Thereof, the following preliminary conclusions can be drawn: - The Ti content in natural bentonites is concentrated mainly in the so-called clay fraction. Ti occurs therein either as separate small TiO 2 particles (Rokle, Opalinus Clay, Illite du Puy) or as structural Ti. As indicated by the study of Karnland et al. (2006), the properties of natural bentonites are not affected by the presence of Ti. In that study, the bulk properties (swelling pressure, hydraulic conductivity) were very similar for the different bentonites containing variable Ti content, ranging from 0.1 to 4.8 weight % TiO 2 in the purified clay fractions. The transfer rates of Ti from the metallic source, even in reactive powder form, to the clay are very low and no enrichment above background concentrations after several months could be observed. In order to obtain measurable effects, both the corrosion process must be increased and the background concentration must be reduced. Tests with Ti-free clay material at increased temperature are still ongoing and will hopefully enable identification of reacted Ti species. (authors)

  20. Description and preliminary results of a 100 square meter rain gauge

    Science.gov (United States)

    Grimaldi, Salvatore; Petroselli, Andrea; Baldini, Luca; Gorgucci, Eugenio

    2018-01-01

    Rainfall is one of the most crucial processes in hydrology, and the direct and indirect rainfall measurement methods are constantly being updated and improved. The standard instrument used to measure rainfall rate and accumulation is the rain gauge, which provides direct observations. Though the small dimension of the orifice allows rain gauges to be installed anywhere, it also causes errors due to the splash and wind effects. To investigate the role of the orifice dimension, this study, for the first time, introduces and demonstrates an apparatus for observing rainfall called a giant-rain gauge that is characterised by a collecting surface of 100 m2. To discuss the new instrument and its technical details, a preliminary analysis of 26 rainfall events is provided. The results suggest that there are significant differences between the standard and proposed rain gauges. Specifically, major discrepancies are evident for low time aggregation scale (5, 10, and 15 min) and for high rainfall intensity values.

  1. A preliminary investigation of the relationship between sensory processing and social play in autism spectrum disorder.

    Science.gov (United States)

    Miller Kuhaneck, Heather; Britner, Preston A

    2013-01-01

    There are well-documented play deficits in autism beginning with infant object and social play. To create effective interventions, the predictors of play deficits in autism must be established. Individuals with autism spectrum disorder (ASD) frequently report sensory processing difficulties including poor praxis; however, these are potential predictors of play that have not been well studied. Using a data set of 162 individuals with ASD, this study examined the direct and indirect relationships between sensory processing and social play performance via structural equation modeling. The best fitting model suggested that sensory system functions predict praxis and play in combination, providing preliminary evidence that sensory functions are related to social play in combination with praxis in children with ASD. The findings suggest future avenues for research. [OTJR: Occupation, Participation and Health 2013;33(3):159-167.]. Copyright 2013, SLACK Incorporated.

  2. Potato contract farming and ‘privileged spaces’: preliminary insights from rural Maharashtra

    Directory of Open Access Journals (Sweden)

    Vicol, Mark

    2014-09-01

    Full Text Available The emergence of modern value chain schemes such as contract farming in rural India are exposing households to new forms of agricultural production. Evidently, the spread of such schemes in India will have spatial implications for rural development. This short communication offers preliminary insights of the contours of these spatial implications from a case study of potato contract farming in three villages in Maharashtra, India. It is proposed that studies that combine a local-scale livelihoods approach with global value chain analysis can strengthen understanding of agricultural change and rural development by grounding value chain analysis in the place-based everyday realities of rural households. Using this approach to adopt an evolutionary view of livelihoods and value chains will lead to a much deeper understanding of possible future development pathways for rural households under conditions of agricultural transformation.

  3. Cortical gyrification in autistic and Asperger disorders: a preliminary magnetic resonance imaging study.

    Science.gov (United States)

    Jou, Roger J; Minshew, Nancy J; Keshavan, Matcheri S; Hardan, Antonio Y

    2010-12-01

    The validity of Asperger disorder as a distinct syndrome from autism is unclear partly because of the paucity of differentiating neurobiological evidence. Frontal lobe cortical folding between these disorders was compared using the gyrification index. Twenty-three boys underwent structural magnetic resonance imaging: 6 with high-functioning autism, 9 with Asperger disorder, and 8 controls. Using the first coronal slice anterior to the corpus callosum, total and outer cortical contours were traced to calculate the gyrification index. This index was also calculated for superior and inferior regions to examine dorsolateral prefrontal and orbitofrontal cortices, respectively. Analysis of variance revealed differences in the left inferior gyrification index, which was higher in the autism group compared with Asperger and control groups. There were no differences in age, intelligence quotient, and brain volume. These preliminary findings suggest that cortical folding may be abnormally high in the frontal lobe in autism but not Asperger disorder, suggesting distinct frontal lobe neuropathology.

  4. Geology of the Mohon Mountain volcanic field, Yavapai and Mohave Counties, Arizona: a preliminary report

    International Nuclear Information System (INIS)

    Simmons, A.M.; King, J.S.

    1987-01-01

    Field mapping has produced a preliminary picture of Mohon Mountain as a composite volcano, in which pyroclastic ash and larger tephra erupted alternately with flows of rhyodacite and dacite. An analog study which uses imagery of lunar and Martian features will compare the overall shape of the vent complex, including its breached southern flank and satellite vents, to similar landforms found on Mars and the Moon which are believed to have formed similar processes. Ash flow sheets were hypothesized to comprise the outer slopes of Olympus Mons suggesting that explosive eruptions which are more volatile-rich than those which produce basalt flows are not confined to terrestrial settings but may also be found on bodies such as Mars, which have a thicker crust and deeper magma source in the mantle. The analog study will explore further evidence for explosive eruptions on Mars and the Moon

  5. Direction finding of night-time whistlers at very low latitudes in China - Preliminary results

    Science.gov (United States)

    Xu, J. S.; Tian, M.; Tang, C. C.; Hayakawa, M.; Ohta, K.; Shimakura, S.

    1989-09-01

    Simultaneous direction finding measurements of equatorial latitude whistlers have been performed in January 1988 at three stations in China, including Zhanjiang (geomagnetic latitude 10.0 deg N), Guilin (14.1 deg), and Wuchang (19.4 deg). The preliminary analyses for a particular day have shown experimentally that there is a single-valued dispersion value (D = 10.5 sq rt s) for nighttime whistlers at the three stations and that their ionospheric exit region is located just in the zenith of Zhanjiang, with an approximately right-handed circular polarization. This finding lends strong evidence to a previous implication, inferred from the simultaneous multistation network, that there is a preferred propagation channel at a geomagnetic latitude aroung 10 deg.

  6. Cortical Gyrification in Autistic and Asperger Disorders: A Preliminary Magnetic Resonance Imaging Study

    Science.gov (United States)

    Jou, Roger J.; Minshew, Nancy J.; Keshavan, Matcheri S.; Hardan, Antonio Y.

    2011-01-01

    The validity of Asperger disorder as a distinct syndrome from autism is unclear partly due to the paucity of differentiating neurobiological evidence. Frontal lobe cortical folding between these disorders was compared using the gyrification index. Twenty-three boys underwent structural magnetic resonance imaging: six with high-functioning autism, nine with Asperger disorder, and eight controls. Using the first coronal slice anterior to the corpus callosum, total and outer cortical contours were traced to calculate the gyrification index. This index was also calculated for superior and inferior regions to examine dorsolateral prefrontal and orbitofrontal cortices, respectively. Analysis of variance revealed differences in the left inferior gyrification index, which was higher in the autism group compared to Asperger and control groups. There were no differences in age, intelligence quotient, and brain volume. These preliminary findings suggest that cortical folding may be abnormally high in the frontal lobe in autism but not Asperger disorder, suggesting distinct frontal lobe neuropathology. PMID:20413799

  7. Plant exploitation during the early Natufian in north-eastern Jordan: preliminary results from Shubayqa 1

    DEFF Research Database (Denmark)

    Otaegui, Amaia Arranz; Richter, Tobias

    on this time period is the low density of plant remains preserved in archaeological sites. This largely contrasts with the extraordinary well-preserved archaeobotanical assemblage found at the Early and Late Natufian Shubayqa 1. In this paper, we present the preliminary results of wood charcoal and non......In spite of southwest Asia being one of the areas in the world where archaeobotanists have worked longest, information regarding plant exploitation during the Natufian period is still patchy and more materials and well-sampled sites are needed. One of the problems faced by archaeobotanists working......-woody plant analyses from two in situ hearth structures, along with a summary of the available evidence at other contemporary early Natufian sites. In terms of past vegetation, the results show the presence of wetland species indicating a more forested and wet environment during the early Natufian, which...

  8. Archaeogeophysical investigations in Tiwanaku: preliminary results

    Science.gov (United States)

    Masini, Nicola; Sileo, Maria; Lasaponara, Rosa; Leucci, Giovanni; Orefici, Giuseppe; Rizzo, Enzo

    2017-04-01

    -1450) Tiwanaku was characterized by the resurgence of regional identities and polities In spite of the rich archaeological record numerous issues, related to the function and the extension of Tiwanaku, need to be investigated especially in the monumental core which includes the pyramid of Akapana, and other ceremonial places such Kalasasaya, Putuni and Kantatallita. To this aims some geophysical investigations were performed in 2009 and 2014 in the context of multidisciplinary research including the use of satellite remote sensing [8]. This paper deals with the discussion of preliminary results of geomagnetic and GPR investigations, some of which have been verified by trial archaeological excavations which have unearthed some buried structures, improving the knowledge of the ceremonial areas of Tiwanaku. References [1] Lasaponara R., Leucci G., Masini N., Persico R., Scardozzi G., Towards an operative use of remote sensing for exploring the past using satellite data: The case study of Hierapolis (Turkey), Remote sensing of Environment, 174 (2016) : 148-164, doi:10.1016/j.rse.2015.12.016 [2] Masini N., Lasaponara R., Rizzo E., Orefici G. 2012. Integrated Remote Sensing Approach in Cahuachi (Peru): Studies and Results of the ITACA Mission (2007-2010), In: Lasaponara R., Masini N. (Eds) 2012, Satellite Remote Sensing: a new tool for Archaeology, Springer, Verlag Berlin Heidelberg, ISBN 978-90-481-8800-0, doi: 10.1007/978-90-481-8801-7_14; pp. 307-344 [3] Rizzo E., Masini N., Lasaponara R., Orefici G. 2010, ArchaeoGeophysical methods in the Templo del Escalonado (Cahuachi, Nasca, Perù), Near Surface Geophysics 8 (5), 433-439, doi:10.3997/1873-0604.2010030 [4] Masini N., Rizzo E., Lasaponara R., and Orefici G. 2008, Integrated remote sensing techniques for the detection of buried archaeological adobe structures: preliminary results in Cahuachi (Peru), Advances in Geosciences, 19, 75-82 [5] Lasaponara R., Leucci G., Masini N., Persico R. 2014. Investigating archaeological looting

  9. Weighing evidence: quantitative measures of the importance of bitemark evidence.

    Science.gov (United States)

    Kittelson, J M; Kieser, J A; Buckingham, D M; Herbison, G P

    2002-12-01

    Quantitative measures of the importance of evidence such as the "likelihood ratio" have become increasingly popular in the courtroom. These measures have been used by expert witnesses formally to describe their certainty about a piece of evidence. These measures are commonly interpreted as the amount by which the evidence should revise the opinion of guilt, and thereby summarize the importance of a particular piece of evidence. Unlike DNA evidence, quantitative measures have not been widely used by forensic dentists to describe their certainty when testifying about bitemark evidence. There is, however, no inherent reason why they should not be used to evaluate bitemarks. The purpose of this paper is to describe the likelihood ratio as it might be applied to bitemark evidence. We use a simple bitemark example to define the likelihood ratio, its application, and interpretation. In particular we describe how the jury interprets the likelihood ratio from a Bayesian perspective when evaluating the impact of the evidence on the odds that the accused is guilty. We describe how the dentist would calculate the likelihood ratio based on frequentist interpretations. We also illustrate some of the limitations of the likelihood ratio, and show how those limitations apply to bitemark evidence. We conclude that the quality of bitemark evidence cannot be adequately summarized by the likelihood ratio, and argue that its application in this setting may be more misleading than helpful.

  10. Evidence in dentistry guidelines

    Directory of Open Access Journals (Sweden)

    Cristiane Rufino Macedo

    Full Text Available CONTEXT AND OBJECTIVE: Guidelines are suggestions for clinical practice based on the best available scientific evidence. Nevertheless, in drafting such guidelines, existing systematic reviews are often ignored and are replaced by general consensuses. This ends up compromising the quality of the instructions through bias. Our objective was to investigate whether Cochrane systematic reviews were present among the bibliographic references of prevention and treatment guidelines for dentistry that have been published in databases. DESIGN AND SETTING: This retrospective, observational study was conducted at the Brazilian Cochrane Center. METHODS: The databases were searched for guidelines. Any guidelines obtained were then checked to find whether Cochrane systematic reviews were present in the bibliographic references of the guidelines. In their absence, we checked whether such reviews had not been included because no reviews existed yet, or because such reviews had not been consulted despite already existing. RESULTS: 223 studies were initially selected; of these, 77 were excluded. Of the 146 guidelines included, 46 could have made reference to existing systematic reviews, but only 13 studies did so. Among these 13 studies, eight were systematic reviews following Cochrane methodology. Thirty-three guidelines had not been drafted using published systematic reviews as references, and 100 guidelines had been unable to use Cochrane references because no reviews existed yet. CONCLUSION: It is necessary to increase awareness of the importance of using systematic reviews in drafting dentistry guidelines. Likewise, it is necessary to develop systematic reviews that answer questions on the various topics that remain unanswered.

  11. Evidence-based policy

    DEFF Research Database (Denmark)

    Vohnsen, Nina Holm

    2013-01-01

    A current ambition in welfare states as diverse as Denmark, the UK, and in the USA is to base political decision making on rigorous research (Cartwright et al 2009; Mulgan 2009; Bason 2010). Sound as this might seem the ambition has nevertheless been problematized by both policy-makers and the re......A current ambition in welfare states as diverse as Denmark, the UK, and in the USA is to base political decision making on rigorous research (Cartwright et al 2009; Mulgan 2009; Bason 2010). Sound as this might seem the ambition has nevertheless been problematized by both policy......-makers and the research community (e.g. Boden & Epstein 2006; House of Commons 2006; Cartwright et al 2009; Rod 2010; Vohnsen 2011). This article intends to draw out some general pitfalls in the curious meeting of science and politics by focusing on a particular attempt to make evidence-based legislation in Denmark (for...... a full account, see Vohnsen 2011). These insights will be relevant for the anthropological researcher of legislative processes who wishes to move beyond a merely discursive approach to the study of policy and politics....

  12. Observer and student ratings of the class environment: A preliminary investigation of convergence.

    Science.gov (United States)

    Nelson, Peter M; Reddy, Linda A; Dudek, Christopher M; Lekwa, Adam J

    2017-12-01

    The present study examined the relationship between student and observer ratings of the class environment. More specifically, class responses on the Responsive Environmental Assessment for Classroom Teaching (REACT; Theodore J. Christ & Colleagues, 2015) were compared with observer ratings on the Classroom Strategies Assessment System-Observer Form (Reddy, Fabiano, & Dudek, 2013). This study included 38 teachers and 582 students from 5 high-poverty schools. Observational data were reported as discrepancy scores, which reflect the difference between the recommended frequency and observed frequency of specific instructional and behavioral management strategies for classroom teachers. Pearson correlations were used to evaluate the relationship between the 6 subscales included on the REACT and the 9 subscales included on the CSAS-O. Results provide preliminary evidence for the relationship between observer and student ratings of the class environment. More specifically, as discrepancy scores decreased, student ratings of the class environment tended to be more positive. The relationship between the REACT and the CSAS-O differed across subscales; however, in general, subscales that were conceptually similar tended to demonstrate stronger relationships than subscales that were conceptually distinct. Thus, the observed results also provide preliminary evidence that students are capable of discriminating between the quality of different components of the class environment. The potential use of both observer and student ratings of the class environment to provide teachers with a more robust and comprehensive reference for professional development purposes is discussed within the context of a tiered model of support. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Preliminary characterization of abandoned septic tank systems. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    This report documents the activities and findings of the Phase I Preliminary Characterization of Abandoned Septic Tank Systems. The purpose of the preliminary characterization activity was to investigate the Tiger Team abandoned septic systems (tanks and associated leachfields) for the purpose of identifying waste streams for closure at a later date. The work performed was not to fully characterize or remediate the sites. The abandoned systems potentially received wastes or effluent from buildings which could have discharged non-domestic, petroleum hydrocarbons, hazardous, radioactive and/or mixed wastes. A total of 20 sites were investigated for the preliminary characterization of identified abandoned septic systems. Of the 20 sites, 19 were located and characterized through samples collected from each tank(s) and, where applicable, associated leachfields. The abandoned septic tank systems are located in Areas 5, 12, 15, 25, and 26 on the Nevada Test Site.

  14. Preliminary characterization of abandoned septic tank systems. Volume 1

    International Nuclear Information System (INIS)

    1995-12-01

    This report documents the activities and findings of the Phase I Preliminary Characterization of Abandoned Septic Tank Systems. The purpose of the preliminary characterization activity was to investigate the Tiger Team abandoned septic systems (tanks and associated leachfields) for the purpose of identifying waste streams for closure at a later date. The work performed was not to fully characterize or remediate the sites. The abandoned systems potentially received wastes or effluent from buildings which could have discharged non-domestic, petroleum hydrocarbons, hazardous, radioactive and/or mixed wastes. A total of 20 sites were investigated for the preliminary characterization of identified abandoned septic systems. Of the 20 sites, 19 were located and characterized through samples collected from each tank(s) and, where applicable, associated leachfields. The abandoned septic tank systems are located in Areas 5, 12, 15, 25, and 26 on the Nevada Test Site

  15. PRELIMINARY DESIGN BASIS EVENT ANALYSIS OF DOE SNF

    International Nuclear Information System (INIS)

    S. Tsai

    1999-01-01

    The purpose of this document is to perform a preliminary design basis event (DBE) analysis of the DOE Spent Nuclear Fuel (SNF) waste form. The objective of the analysis is to determine any preclosure safety impacts of the waste form on the Monitored Geologic Repository (MGR). The scope of this analysis is to determine the offsite dose consequences and associated frequencies of selected DBEs for systems handling disposable canisters that bound all surface and subsurface off-normal events, and to compare these results against regulatory limits. The results of this work are preliminary and are intended to be used to establish a set of preliminary MGR and waste form requirements, to identify mitigation or prevention features that may be required to meet regulatory limits, and to provide input to the Site Recommendation (SR) report. This document is prepared in accordance with the associated development plan (Civilian Radioactive Waste Management System Management and Operating Contractor [CRWMS M andO] 1999g)

  16. Preliminary studies on vigna unguiculata trypsin inhibitor

    International Nuclear Information System (INIS)

    Sofyan, Rochestri

    1980-01-01

    Investigation on the presence of trypsin inhibitor in vigna unguiculata at three stages of ripeness, i.e. as young beans obtained from first harvest usually consumed as vegetable, seed from beans picked two weeks after the first harvest and seed from beans picked four weeks after the first harvest, has been carried out. The conclusion drawn from this experiment showed the existence of trypsin inhibitor at those stages of ripeness. It is found that the older the stage of ripeness the greater the specific activity of trypsin inhibitor. Evidently the heated extract loss its antitryptic activity progressively with increasing heatings periods. Extract heated on a water bath at a constant temperature of 78 deg C during 20, 40 and 60 minutes, loss its antitryptic activity of about 53, 78 and 96% respectively. (author)

  17. [Tuscan Chronic Care Model: a preliminary analysis].

    Science.gov (United States)

    Barbato, Angelo; Meggiolaro, Angela; Rossi, Luigi; Fioravanti, C; Palermita, F; La Torre, Giuseppe

    2015-01-01

    the aim of this study is to present a preliminary analysis of efficacy and effectiveness of a model of chronically ill care (Chronic Care Model, CCM). the analysis took into account 106 territorial modules, 1016 General Practitioners and 1,228,595 patients. The diagnostic and therapeutic pathways activated (PDTA), involved four chronic conditions, selected according to the prevalence and incidence, in Tuscany Region: Diabetes Mellitus (DM), Heart Failure (SC), Chronic Obstructive Pulmonary Disease (COPD) and stroke. Six epidemiological indicators of process and output were selected, in order to measure the model of care performed, before and after its application: adherence to specific follow-up for each pathology (use of clinical and laboratory indicators), annual average of expenditure per/capita/euro for diagnostic tests, in laboratory and instrumental, average expenditure per/capita/year for specialist visits; hospitalization rate for diseases related to the main pathology, hospitalization rate for long-term complications and rate of access to the emergency department (ED). Data were collected through the database; the differences before and after the intervention and between exposed and unexposed, were analyzed by method "Before-After (Controlled and Uncontrolled) Studies". The impact of the intervention was calculated as DD (difference of the differences). DM management showed an increased adhesion to follow-up (DD: +8.1%), and the use of laboratory diagnostics (DD: +4,9 €/year/pc), less hospitalization for long-term complications and for endocrine related diseases (DD respectively: 5.8/1000 and DD: +1.2/1000), finally a smaller increase of access to PS (DD: -1.6/1000), despite a slight increase of specialistic visits (DD: +0,38 €/year/pc). The management of SC initially showed a rising adherence to follow-up (DD: +2.3%), a decrease of specialist visits (DD:E 1.03 €/year/pc), hospitalization and access to PS for exacerbations (DD: -4.4/1000 and DD: -6

  18. Preliminary Phase Field Computational Model Development

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yulan [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hu, Shenyang Y. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Xu, Ke [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Suter, Jonathan D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McCloy, John S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Bradley R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-12-15

    experiments, special experimental methods were devised to create similar boundary conditions in the iron films. Preliminary MFM studies conducted on single and polycrystalline iron films with small sub-areas created with focused ion beam have correlated quite well qualitatively with phase-field simulations. However, phase-field model dimensions are still small relative to experiments thus far. We are in the process of increasing the size of the models and decreasing specimen size so both have identical dimensions. Ongoing research is focused on validation of the phase-field model. Validation is being accomplished through comparison with experimentally obtained MFM images (in progress), and planned measurements of major hysteresis loops and first order reversal curves. Extrapolation of simulation sizes to represent a more stochastic bulk-like system will require sampling of various simulations (i.e., with single non-magnetic defect, single magnetic defect, single grain boundary, single dislocation, etc.) with distributions of input parameters. These outputs can then be compared to laboratory magnetic measurements and ultimately to simulate magnetic Barkhausen noise signals.

  19. Preliminary Earthquake Hazard Map of Afghanistan

    Science.gov (United States)

    Boyd, Oliver S.; Mueller, Charles S.; Rukstales, Kenneth S.

    2007-01-01

    . Deformation here is expressed as a belt of major, north-northeast-trending, left-lateral strike-slip faults and abundant seismicity. The seismicity intensifies farther to the northeast and includes a prominent zone of deep earthquakes associated with northward subduction of the Indian plate beneath Eurasia that extends beneath the Hindu Kush and Pamirs Mountains. Production of the seismic hazard maps is challenging because the geological and seismological data required to produce a seismic hazard model are limited. The data that are available for this project include historical seismicity and poorly constrained slip rates on only a few of the many active faults in the country. Much of the hazard is derived from a new catalog of historical earthquakes: from 1964 to the present, with magnitude equal to or greater than about 4.5, and with depth between 0 and 250 kilometers. We also include four specific faults in the model: the Chaman fault with an assigned slip rate of 10 mm/yr, the Central Badakhshan fault with an assigned slip rate of 12 mm/yr, the Darvaz fault with an assigned slip rate of 7 mm/yr, and the Hari Rud fault with an assigned slip rate of 2 mm/yr. For these faults and for shallow seismicity less than 50 km deep, we incorporate published ground-motion estimates from tectonically active regions of western North America, Europe, and the Middle East. Ground-motion estimates for deeper seismicity are derived from data in subduction environments. We apply estimates derived for tectonic regions where subduction is the main tectonic process for intermediate-depth seismicity between 50- and 250-km depth. Within the framework of these limitations, we have developed a preliminary probabilistic seismic-hazard assessment of Afghanistan, the type of analysis that underpins the seismic components of modern building codes in the United States. The assessment includes maps of estimated peak ground-acceleration (PGA), 0.2-second spectral acceleration (SA), and 1.0-secon

  20. A preliminary bending fatigue spectrum for steel monostrand cables

    DEFF Research Database (Denmark)

    Winkler, Jan; Fischer, Gregor; Georgakis, Christos T.

    2011-01-01

    service life expectancy. The presented preliminary bending fatigue spectrum of high-strength monostrands is currently unavailable in the published literature. The presented results provide relevant information on the bending mechanism and fatigue characteristics of monostrand steel cables in tension......This paper presents the results of the experimental study on the bending fatigue resistance of high-strength steel monostrand cables. From the conducted fatigue tests in the high-stress, low-cycle region, a preliminary bending fatigue spectrum is derived for the estimation of monostrand cable...... and flexure and show that localized cable bending has a pronounced influence on the fatigue resistance of cables under dynamic excitations....

  1. Preliminary analysis of alternative fuel cycles for proliferation evaluation

    International Nuclear Information System (INIS)

    Steindler, M.J.; Ripfel, H.C.F.; Rainey, R.H.

    1977-01-01

    The ERDA Division of Nuclear Research and Applications proposed 67 nuclear fuel cycles for assessment as to their nonproliferation potential. The object of the assessment was to determine which fuel cycles pose inherently low risk for nuclear weapon proliferation while retaining the major benefits of nuclear energy. This report is a preliminary analysis of these fuel cycles to develop the fuel-recycle data that will complement reactor data, environmental data, and political considerations, which must be included in the overall evaluation. This report presents the preliminary evaluations from ANL, HEDL, ORNL, and SRL and is the basis for a continuing in-depth study

  2. The friction of polymers around Tg,Tm : Preliminary results

    DEFF Research Database (Denmark)

    Sivebæk, Ion Marius; Samoilov, V N; Persson, B N J

    We present Molecular Dynamics calculations involving polymers of different lengths. Polymers with lengths from 20 to 1400 carbon atoms are considered. The systems are able to simulate friction between polymer surfaces and polymer against metal. The results we present are very preliminary and they......We present Molecular Dynamics calculations involving polymers of different lengths. Polymers with lengths from 20 to 1400 carbon atoms are considered. The systems are able to simulate friction between polymer surfaces and polymer against metal. The results we present are very preliminary...

  3. Energy Efficient Engine: Control system preliminary definition report

    Science.gov (United States)

    Howe, David C.

    1986-01-01

    The object of the Control Preliminary Definition Program was to define a preliminary control system concept as a part of the Energy Efficient Engine program. The program was limited to a conceptual definition of a full authority digital electronic control system. System requirements were determined and a control system was conceptually defined to these requirements. Areas requiring technological development were identified and a plan was established for implementing the identified technological features, including a control technology demonstration. A significant element of this program was a study of the potential benefits of closed-loop active clearance control, along with laboratory tests of candidate clearance sensor elements for a closed loop system.

  4. Preliminary design package for prototype solar heating system

    Energy Technology Data Exchange (ETDEWEB)

    1978-12-01

    A summary is given of the preliminary analysis and design activity on solar heating systems. The analysis was made without site specific ata other than weather; therefore, the results indicate performance expected under these special conditions. Major items in this report include systeem candidates, design approaches, trade studies and other special data required to evaluate the preliminary analysis and design. The program calls for the development and delivery of eight prototype solar heating and coolin systems for installation and operational test. Two-heating and six heating and cooling units will be delivered for Single Family Residences (SFR), Multi-Family Residences (MFR) and commercial applications.

  5. Preliminary design studies of an advanced general aviation aircraft

    Science.gov (United States)

    Barrett, Ron; Demoss, Shane; Dirkzwager, AB; Evans, Darryl; Gomer, Charles; Keiter, Jerry; Knipp, Darren; Seier, Glen; Smith, Steve; Wenninger, ED

    1991-01-01

    The preliminary design results are presented of the advanced aircraft design project. The goal was to take a revolutionary look into the design of a general aviation aircraft. Phase 1 of the project included the preliminary design of two configurations, a pusher, and a tractor. Phase 2 included the selection of only one configuration for further study. The pusher configuration was selected on the basis of performance characteristics, cabin noise, natural laminar flow, and system layouts. The design was then iterated to achieve higher levels of performance.

  6. Communication skills in blind children: a preliminary investigation.

    Science.gov (United States)

    James, D M; Stojanovik, V

    2007-01-01

    There are anecdotal reports that blind children sometimes use language inappropriately, but there has been no recent systematic investigation of the communication skills of children with congenital blindness. The aim of the present study was to conduct a preliminary investigation of the communication skills of a group of children with congenital blindness. The parents of eight congenitally blind children completed the Children's Communication Checklist-2. The checklist ratings showed that the communication profiles of a large proportion of the group warranted clinical investigation or were indicative of a communication disorder. The results from this preliminary investigation support the need for a larger study on the communication skills of children with congenital blindness.

  7. Design Preliminaries for Direct Drive under Water Wind Turbine Generator

    DEFF Research Database (Denmark)

    Leban, Krisztina Monika; Ritchie, Ewen; Argeseanu, Alin

    2012-01-01

    This paper focuses on the preliminary design process of a 20 MW electric generator. The application calls for an offshore, vertical axis, direct drive wind turbine. Arguments for selecting the type of electric machine for the application are presented and discussed. Comparison criteria for deciding...... on a type of machine are listed. Additional constraints emerging from the direct drive, vertical axis concepts are considered. General rules and a preliminary algorithm are discussed for the machine selected to be most suitable for the imposed conditions....

  8. Preliminary environmental site assessments in New York City

    International Nuclear Information System (INIS)

    Lundy, P.; Gasson, D.R.; Longendyke, S.T.

    1991-01-01

    Preliminary Environmental Site Assessments are often performed prior to real estate transactions or refinancing. These assessments are typically performed for real estate buyers, sellers and lending institutions. Undertaking a Preliminary Environmental Site Assessment in New York City can often be quite complex and time-consuming. This is due, in part, to the age and density of buildings in the city as well as the myriad of regulatory agencies with jurisdiction over environmental issues. This paper will discuss how environmental assessments are performed with a special emphasis on building in New York City. In includes hazardous wastes management for Radon, PCB's and asbestos

  9. Preliminary Validation and Verification Plan for CAREM Reactor Protection System

    International Nuclear Information System (INIS)

    Fittipaldi, Ana; Maciel Felix

    2000-01-01

    The purpose of this paper, is to present a preliminary validation and verification plan for a particular architecture proposed for the CAREM reactor protection system with software modules (computer based system).These software modules can be either own design systems or systems based in commercial modules such as programmable logic controllers (PLC) redundant of last generation.During this study, it was seen that this plan can also be used as a validation and verification plan of commercial products (COTS, commercial off the shelf) and/or smart transmitters.The software life cycle proposed and its features are presented, and also the advantages of the preliminary validation and verification plan

  10. Preliminary analysis of alternative fuel cycles for proliferation evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Steindler, M. J.; Ripfel, H. C.F.; Rainey, R. H.

    1977-01-01

    The ERDA Division of Nuclear Research and Applications proposed 67 nuclear fuel cycles for assessment as to their nonproliferation potential. The object of the assessment was to determine which fuel cycles pose inherently low risk for nuclear weapon proliferation while retaining the major benefits of nuclear energy. This report is a preliminary analysis of these fuel cycles to develop the fuel-recycle data that will complement reactor data, environmental data, and political considerations, which must be included in the overall evaluation. This report presents the preliminary evaluations from ANL, HEDL, ORNL, and SRL and is the basis for a continuing in-depth study. (DLC)

  11. Evidence and Ethics (Editorial

    Directory of Open Access Journals (Sweden)

    Alison Brettle

    2012-12-01

    Full Text Available Welcome to the December issue of EBLIP, the final issue of my first year as Editor-in-Chief. A year which I have thoroughly enjoyed and one where the fears over what to write in my editorials haven’t materialised. This quarter, ethics has featured quite heavily in my working life so I decided to make this the topic of the editorial, sharing some of my thoughts regarding evidence, ethics and how ethical principles are implemented within the EBLIP journal.Ethics are “principles of conduct or standards of behaviour governing an individual or profession” (Library and Information Science Editorial Committee, 2010, and as individuals or professionals we may be governed by various ethical codes. As I'm sure you know, EBLIP originated in the health domain, where ethical values and ethical research feature strongly. Indeed, by its formal definition, research cannot take place unless “ethical approval” from an appropriate committee has been granted. The practicalities of taking research through the ethical approval process can often be time consuming, and those involved in research need to bear this in mind when planning a project. Each committee will have a slightly different form and process (which can add to the frustration of the researcher, but basically will make their decision to approve on the basis that the research includes obtaining informed consent from participants (i.e., participants know what the research is about and what their involvement will mean; that the research will not cause harm to participants; that confidentiality will be maintained; and that the research undertaken is methodologically rigorous and worthwhile. Preparing a proposal for ethical approval, whilst time consuming, makes the researcher think about all aspects of the research and how it is going to be operationalized, which can save lots of time and effort in the long run and may well also improve the research design. These principles are the same whatever

  12. Evidence-based clinical practice

    DEFF Research Database (Denmark)

    Gluud, Christian

    2002-01-01

    Evidence-based medicine combines the patient's preferences with clinical experience and the best research evidence. Randomized clinical trials are considered the most valid research design for evaluating health-care interventions. However, empirical research shows that intervention effects may be...... practice. By investments in education, applied research, and The Cochrane Collaboration, evidence-based medicine may form a stronger basis for clinical practice.......Evidence-based medicine combines the patient's preferences with clinical experience and the best research evidence. Randomized clinical trials are considered the most valid research design for evaluating health-care interventions. However, empirical research shows that intervention effects may......, and single clinics. Accordingly, there is an urgent need to improve this situation. Guidelines for Good Clinical (Research) Practice, conduct of more trials as multicentre trials, The Consort Statement, and The Cochrane Collaboration may all help in the application of the best research evidence in clinical...

  13. Limitations of Expert Evidence

    Directory of Open Access Journals (Sweden)

    Serpil Salaçin

    1997-10-01

    Full Text Available Limitations of Expert Evidence Edited by Stephen Leadbeatter MB ChB MCRPath ISBN 1 86016 029 8 Printed in Great Britain by Cathedral Print Services Ltd, Salisbury, 1996 Kitap 25 Ekim 1994 te The Royal College of Physicians ve The Royal College of Pathologists tarafından düzenlenen konferanstan sonra hekimlere ve avukatlara konuyu tartışmaya açmak için basılmış. Bilirkişi görüşünün temel filozofisinin, bu görevi yapanlar ve bu hizmeti alanların yapabileceklerinin sınırlarının tartışılması amaçlanmış.Seksen altı sayfadan oluşan kitabın fiatı on iki İngiliz Sterlini. Kitap üç bölüm ve bunların altında toplanan on ana başlıktan oluşmakta. Elinize aldığınızda küçük boyutu ve anlaşılır dili ile hemen okunup bitirelecek kitaplardan sanılıyor. En azından ben böyle düşünmüştüm. Ancak daha L A Tuınberg ve A J Bellinham’ın ön yazısında ben çarpıldım. Değerli yazarların kaleme aldığı başlıklar ve gündeme getirdiği tartışmaların tüm Adli Bilimlerle uğraşanların dikkatle okuması gereken cinsten olduğu kanısındayım. Birinci bölüm The Legal Perspective iki anabaşlıktan oluşuyor, The Criminal legal perspective Honour Judje Martin Stephens tarafından yazılmış,bilirkişi olarak görev yapabilmek için belgelenmiş bir eğitim olması gerektiği, mahkemelerde ya da yazılı raporlarda verilebilecek görüşlerin incelikleri tartışılmış. Bu bölümün ikinci anabaşlığı The civil legal perspective avukat Jennifer Cummin tarafından yazılmış. Toplum gözünde bilirkişinin anlamı ve mahkemenin bilirkişi görüşünü değişmez bilimsel doğru gibi algılayarak düştüğü bilimsel yanılgı ve raporlardaki kavram farkı dile getirilmiş. İkinci Bölüm The Medical And Scientific Perspective başlığı altında Roger C Evans MD Clinical evidence başlığında toplumun hasta tedavisi ve bilirkişilik hizmetinden beklentilerinin unrealistik olduğu ve

  14. Evidence-based clinical practice

    DEFF Research Database (Denmark)

    Garattini, Silvio; Jakobsen, Janus C; Wetterslev, Jørn

    2016-01-01

    was considered through literature searches combined with personal files. Treatments should generally not be chosen based only on evidence from observational studies or single randomised clinical trials. Systematic reviews with meta-analysis of all identifiable randomised clinical trials with Grading...... of Recommendations Assessment, Development and Evaluation (GRADE) assessment represent the highest level of evidence. Even though systematic reviews are trust worthier than other types of evidence, all levels of the evidence hierarchy are under threats from systematic errors (bias); design errors (abuse of surrogate...

  15. When Lack of Evidence Is Evidence of Lack.

    Science.gov (United States)

    Pickering, Neil

    2015-12-01

    In their recent article "A Gentle Ethical Defence of Homeopathy," Levy, Gadd, Kerridge, and Komesaroff use the claim that "lack of evidence is not equivalent to evidence of lack" as a component of their ethical defence of homeopathy. In response, this article argues that they cannot use this claim to shore up their ethical arguments. This is because it is false.

  16. 78 FR 9687 - Prineville Energy Storage, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2013-02-11

    ... Energy Regulatory Commission Prineville Energy Storage, LLC; Notice of Preliminary Permit Application..., 2012, Prineville Energy Storage, LLC, filed an application for a preliminary permit, pursuant to...-hours. Applicant Contact: Mr. Matthew Shapiro, Chief Executive Officer, Prineville Energy Storage, LLC...

  17. Mood disorders and season of presentation: A preliminary study of ...

    African Journals Online (AJOL)

    The relationship between season and mood is complex. This study attempts to clarify one aspect of the relationship: the impact of season on mood in terms of the hypothesised seasonal variation in the presentation of mood disorders at Baragwanath Hospital. Although a preliminary study, the results show a statistically ...

  18. Licensing support system preliminary needs analysis: Volume 1

    International Nuclear Information System (INIS)

    1989-01-01

    This Preliminary Needs Analysis, together with the Preliminary Data Scope Analysis (next in this series of reports), is a first effort under the LSS Design and Implementation Contract toward developing a sound requirements foundation for subsequent design work. Further refinements must be made before requirements can be specified in sufficient detail to provide a basis for suitably specific system specifications. This preliminary analysis of the LSS requirements has been divided into a ''needs'' and a ''data scope'' portion only for project management and scheduling reasons. The Preliminary Data Scope Analysis will address all issues concerning the content and size of the LSS data base; providing the requirements basis for data acquisition, cataloging and storage sizing specifications. This report addresses all other requirements for the LSS. The LSS consists of both computer subsystems and non-computer archives. This study addresses only the computer subsystems, focusing on the Access Subsystems. After providing background on previous LSS-related work, this report summarizes the findings from previous examinations of needs and describes a number of other requirements that have an impact on the LSS. The results of interviews conducted for this report are then described and analyzed. The final section of the report brings all of the key findings together and describes how these needs analyses will continue to be refined and utilized in on-going design activities. 14 refs., 2 figs., 1 tab

  19. A preliminary study of inflammatory markers in non-alcoholic ...

    African Journals Online (AJOL)

    In the present preliminary study an attempt was made to study whether there is an increase in the levels of CRP in CAD patients associated with NASH. CAD patients showed an increase in CRP and serum ferritin levels. In CAD patients with NASH along with an increase in the levels of serum ferittin (p<0.001), the levels of ...

  20. TITAN Legal Weight Truck cask preliminary design report

    International Nuclear Information System (INIS)

    1990-04-01

    The Preliminary Design of the TITAN Legal Weight Truck (LWT) Cask System and Ancillary Equipment is presented in this document. The scope of the document includes the LWT cask with fuel baskets; impact limiters, and lifting and tiedown features; the cask support system for transportation; intermodal transfer skid; personnel barrier; and cask lifting yoke assembly. 75 figs., 48 tabs

  1. A Preliminary Classification of Human Functional Sexual Disorders

    Science.gov (United States)

    Sharpe, Lawrence; And Others

    1976-01-01

    A preliminary classification is presented for functional human sexual disorders. This system is based on objective behavior and reports of distress. Five categories of sexual disorders are proposed, including the behavioral, psychological and informational components of sexual functioning in the individual and the couple. (Author)

  2. Preliminary screening of plant essential oils against larvae of Culex ...

    African Journals Online (AJOL)

    Preliminary screenings of 22 plant essential oils were tested for mortality of the mosquito larvae Culex quinquefasciatus under laboratory conditions. Percent (%) mortality of the mosquito larvae were obtained for each essential oil. At different exposure periods, viz. 1, 3, 6, 12 and 24 h among the 22 plant oils tested, eight ...

  3. PTSD and Impaired Eye Expression Recognition: A Preliminary Study

    Science.gov (United States)

    Schmidt, Jakob Zeuthen; Zachariae, Robert

    2009-01-01

    This preliminary study examined whether posttraumatic stress disorder (PTSD) was related to difficulties in identifying the mental states of others in a group of refugees. Sixteen Bosnian refugees, referred to treatment in an outpatient treatment center for survivors of torture and war-related trauma in Denmark (CETT), were compared to 16 non-PTSD…

  4. Preliminary Evaluation of Some Qualitative Traits of Sugarcane ...

    African Journals Online (AJOL)

    Preliminary Evaluation of Some Qualitative Traits of Sugarcane Germplasm of. North-Western Nigeria. *1L. Abubakar, 2A. ... yield identification than the stable characters. (qualitative characters) such as shape of vegetative ..... characteristics of Saccharum pontaneun clones in culture at Houma Lousiana. International.

  5. PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND THIN LAYER CHROMATOGRAPHY OF RHEUM EMODI

    OpenAIRE

    Mir Ashfaq Ahmad; K. W. Shah; Showkat Ahmad Wani

    2012-01-01

    Preliminary phytochemical investigation of aqueous and methanolic rhizome extracts of Rheum emodi followed by their TLC profiling were carried out. Phytochemical analysis reveals the presence of diverse groups of phytoconstituents in two different extracts (aqueous and methanolic rhizome extracts). Chemical constituents also show different Rf values in two different solvent systems.

  6. a preliminary assessment of groundwater samples around a filling ...

    African Journals Online (AJOL)

    Home

    This paper is a preliminary assessment of groundwater samples around a filling station in Diobu area of Port ... 2- and relatively lower pH than the groundwater. Other authors who have carried out similar researches in the same geological environment include Amojor (1986) and ...... Harikumar, P. S. and Jisha, T. S., 2010.

  7. Preliminary genetic linkage maps of Chinese herb Dendrobium ...

    Indian Academy of Sciences (India)

    2013-08-05

    Aug 5, 2013 ... [Feng S., Zhao H., Lu J., Liu J., Shen B. and Wang H. 2013 Preliminary genetic linkage maps of Chinese herb Dendrobium nobile and. D. moniliforme. J. Genet. 92, 205–212]. Introduction ..... ity, and inbreeding depression make F2 or backcross popu- lations rarely available for genetic linkage mapping ...

  8. PRELIMINARY NOTES ON mE SUNI, NESOTRAGUS MOSCHATUS ...

    African Journals Online (AJOL)

    PRELIMINARY NOTES ON mE SUNI, NESOTRAGUS MOSCHATUS ~'lD. RED DUIKER, CEPHALOPHUS ... it as being "not uncommon at Mkuzi river, but very shy, taking refuge in the tangled scrub of the flats and only coming into the .... The one chased the other, while making a "tchie-tchie" sound, but louder and more ...

  9. A preliminary checklist of the ants (Hymenoptera: Formicidae) of ...

    African Journals Online (AJOL)

    A preliminary species checklist of the ants (Hymenoptera: Formicidae) of. Kakamega Forest, Western Kenya, is presented. The species list is based on specimens sampled from 1999 until 2009, which are deposited in the ant collection of the Zoological Research Museum Koenig, Bonn, Germany, and the Natural History ...

  10. Preliminary comparison of calls of the hybridizing fur seals ...

    African Journals Online (AJOL)

    Preliminary comparison of calls of the hybridizing fur seals Arctocephalus tropicalis and A. gazella. M. St Clair Hill, J.W.H. Ferguson, M.N. Bester, G.I.H. Kerley. Abstract. The Antarctic fur seal (Arctocephalus gazella) and the Subantarctic fur seal (A. tropicalis) hybridize on a relatively small scale at Marion Island. To date the ...

  11. Preliminary studies on the behavioural effects of the methanol ...

    African Journals Online (AJOL)

    The behavioural tests employed were diazepam-induced sleep onset and duration, hole board assay for exploratory activity, mouse beam walk assay for motor coordination, and the staircase test for the detection of anxiolytic compounds. Preliminary phytochemical screening was also carried out on the extract. Results: The ...

  12. Yucca Mountain transportation routes: Preliminary characterization and risk analysis

    International Nuclear Information System (INIS)

    Souleyrette, R.R. II; Sathisan, S.K.; di Bartolo, R.

    1991-01-01

    This report presents appendices related to the preliminary assessment and risk analysis for high-level radioactive waste transportation routes to the proposed Yucca Mountain Project repository. Information includes data on population density, traffic volume, ecologically sensitive areas, and accident history

  13. Preliminary Data from a De Novo Trauma Registry

    African Journals Online (AJOL)

    of morbidity and mortality globally. Trauma registries are a key component of trauma systems in developed countries which have promoted improvement of patient care and outcomes. The experience with trauma registries in low income countries is limited. The current study shares preliminary data from the Kenyatta ...

  14. Carol Ann Duffy: A Preliminary Bibliography | Bala | Gender and ...

    African Journals Online (AJOL)

    Carol Ann Duffy: A Preliminary Bibliography. I Bala. Abstract. No Abstract. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

  15. A Preliminary Assessment of Groundwater Samples around a Filling ...

    African Journals Online (AJOL)

    This paper is a preliminary assessment of groundwater samples around a filling station in Diobu area of Port Harcourt for four years at intervals of two years with a view to determine the level of groundwater pollution. It examines the physiochemical, major ions and heavy metal aspect of groundwater quality around the study ...

  16. Preliminary study on geology, mineral potential and characteristics ...

    African Journals Online (AJOL)

    Preliminary study on geology, mineral potential and characteristics of hot springs from Dallol area, Afar rift, northeastern Ethiopia: Implications for natural ... Although low, the up to 902 ppm TOC concentrations in the hydrothermal fluids could suggest the presence of hydrocarbon containing rocks at depth and/or fluid mixing ...

  17. Mammography examination in Ghana: preliminary survey of patients ...

    African Journals Online (AJOL)

    Profiles of 1,671 patients undergoing diagnostic mammography examination at three Centres in Accra between May and December 2009 were analysed as preliminary survey to formulate a National Breast Screening Policy for Ghana. Employment category, age, body mass index, clinical history and diagnosis were indices ...

  18. Preliminary In Vivo Experiments on Adhesion of Geckos

    Directory of Open Access Journals (Sweden)

    E. Lepore

    2008-01-01

    Full Text Available We performed preliminary experiments on the adhesion of a Tokay gecko on surfaces with different roughness, with or without particles with significant different granulometry, before/after or during the moult. The results were analyzed using the Weibull statistics.

  19. Design, fabrication and preliminary testing of oil expeller for sesame ...

    African Journals Online (AJOL)

    There was need for local production of vegetable oil expeller in order to eliminate problems of shortage of spare parts, maintenance personnel and adaptation for less known oil seeds such as sesame. Preliminary survey on existing oil expellers was carried out. Some physical and mechanical properties of sesame were ...

  20. Preliminary evaluation of the tibial tuberosity-trochlear groove measurement

    DEFF Research Database (Denmark)

    Miles, James Edward; Kirpensteijn, Jolle; Svalastoga, Eiliv Lars

    guide surgical treatment. The TTTG measures tibial tuberosity position relative to the axis of the femoral trochlea. A preliminary investigation of TTTG measurement was performed using the red fox (Vulpes vulpes) cadavers as a morphologically similar and homogenous substitute for dog cadavers. CT...

  1. Preliminary Studies on the Occurrence of Stem Borers and the ...

    African Journals Online (AJOL)

    Preliminary Studies on the Occurrence of Stem Borers and the Incidence of Stalk Rot under Varying Plant Population Densities in Maize. ... heavier cobs and more grains. The results showed that the medium plant density was more desirable from both disease and pest control points of view. JARD Vol. 1 2001: pp. 67-74 ...

  2. A New Silver Complex with Ofloxacin – Preliminary Study

    Directory of Open Access Journals (Sweden)

    Rusu Aura

    2016-06-01

    Full Text Available Objective: Silver complexes of antibacterial quinolones have the potential advantage of combining the antibacterial activity of silver and fluoroquinolones. The objective of our study was the preparation and the preliminary physico-chemical characterization of a silver complex with ofloxacin.

  3. Preliminary Development and Validation of a Measure of Relationship Authenticity

    Science.gov (United States)

    Lopez, Frederick G.; Rice, Kenneth G.

    2006-01-01

    The authors describe the preliminary development and validation of the Authenticity in Relationships Scale. An initial pool of 37 items addressing various elements of the proposed definition of "relationship authenticity" was administered to 2 independent samples of undergraduates (N = 487) who acknowledged being in a current romantic…

  4. A preliminary assessment of the potential risks from electrical ...

    African Journals Online (AJOL)

    concern in Kenya, 17 (71 %) face a high risk of direct interactions with electrical infrastructure. Priority species ... A rapid preliminary risk assessment of electrical infrastructure was conducted in two areas of Kenya: i) ..... The fundamentals and practice of Overhead Line Maintenance (132kV and above), pp217-245. Eskom ...

  5. Preliminary System Design of the SWRL Financial System.

    Science.gov (United States)

    Ikeda, Masumi

    The preliminary system design of the computer-based Southwest Regional Laboratory's (SWRL) Financial System is outlined. The system is designed to produce various management and accounting reports needed to maintain control of SWRL operational and financial activities. Included in the document are descriptions of the various types of system…

  6. Bats roosting in public buildings: A preliminary assessment from ...

    African Journals Online (AJOL)

    Madagascar has many synanthropic bat species but relatively little is known about how people interact with them. A preliminary assessment on the presence of bats in buildings and their interactions with people was conducted in the eastern town of Moramanga. Fifty of the 156 buildings were reported to contain active bat ...

  7. A Preliminary Study toward Consistent Soil Moisture from AMSR2

    NARCIS (Netherlands)

    Parinussa, R.M.; Holmes, T.R.H.; Wanders, N.; Dorigo, W.A.; de Jeu, R.A.M.

    2015-01-01

    A preliminary study toward consistent soil moisture products from the Advanced Microwave Scanning Radiometer 2 (AMSR2) is presented. Its predecessor, the Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E), has providedEarth scientists with a consistent and continuous global

  8. Preliminary observations on the occurrence of lymphatic filariasis in ...

    African Journals Online (AJOL)

    Preliminary observations on the occurrence of lymphatic filariasis in Cross River State, Nigeria. EI Braise, B Ikpeme, E Edet, I Atting, UF Ekpo, B Esu, OO Kale. Abstract. A situation analysis of the occurrence of Lymphatic Filariasis (LF) in Cross River State, Nigeria, was conducted within the period November 2000 and March ...

  9. Metabolic Control with Insulin Pump Therapy: Preliminary Experience

    Directory of Open Access Journals (Sweden)

    Shang-Ren Hsu

    2008-07-01

    Conclusion: Our preliminary experience demonstrated the effectiveness of insulin pump therapy for both type 1 and type 2 diabetic patients. The reduction in their HbA1C values was both statistically and clinically significant. This treatment should be considered for patients poorly controlled by subcutaneous insulin injection therapy.

  10. Preliminary thoughts on the data acquisition for the next generation ...

    Indian Academy of Sciences (India)

    Abstract. Preliminary thoughts about the data acquisition system to be developed for the next generation of large area silicon tracker are presented in this paper. This paper describes the set of data delivered by these tracking systems, and the various stages of processing and data flow transmission from the front-end chip ...

  11. Synthesis, photophysical and preliminary investigation of the dye ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 125; Issue 1. Synthesis, photophysical and preliminary investigation of the dye-sensitized solar cells properties of functionalized anthracenyl-based bipyridyl and phenanthrolyl Ru(II) complexes. Adewale O Adeloye Peter A Ajibade Frances R Cummings Lukas J Le ...

  12. Preliminary Study on the Use of Urea Activated Melon ( Citrullus ...

    African Journals Online (AJOL)

    Preliminary Study on the Use of Urea Activated Melon ( Citrullus colocynthis ) Husk in the Adsorption of Cadmium from Waste Water. ... Experimental data were also evaluated to find out kinetic characteristics of the adsorption process. Adsorption ... Keywords: Bioadsorption, Cadmium removal, Waste water, Melon husk ...

  13. A preliminary report on locomotory activity in wild and captive ...

    African Journals Online (AJOL)

    The locomotory activity of a free-ranging, male Chrysospalax trevelyani was monitored for five days in the Amatola Forest, Ciskei, using radio telemetry. In addition, locomotory activity of a captive juvenile male and adult female C. trevelyani was monitored in a special laboratory enclosure for 30 days. Preliminary results ...

  14. Medical Audit: A Nigerian Teaching Hospital's Preliminary Experience

    African Journals Online (AJOL)

    The definition, historical background, aims dimensions and the characteristics of medical audit as well as the indices to be measured in a medical audit exercise are highlighted. The preliminary experience of the University of Ilorin Teaching Hospital (UITH) in the planning, implementation and monitoring of a viable medical ...

  15. Preliminary thoughts on the data acquisition for the next generation ...

    Indian Academy of Sciences (India)

    Preliminary thoughts about the data acquisition system to be developed for the next generation of large area silicon tracker are presented in this paper. This paper describes the set of data delivered by these tracking systems, and the various stages of processing and data flow transmission from the front-end chip sitting on ...

  16. Preliminary analysis of the nestedness patterns of Montane forest ...

    African Journals Online (AJOL)

    Previous biogeographical studies of forest avifaunal compositions of mountains in the Eastern Arc archipelago have focused primarily on patterns of species richness and the effects of montane area and isolation. This preliminary investigation examines species composition in terms of nestedness patterns for 12 mountains ...

  17. Preliminary Phytochemical Screening of Fresh and Dried Moringa ...

    African Journals Online (AJOL)

    The preliminary phytochemical screening of the crude aqueous extract of fresh and dried Moringa oleifera leaves, of the organic solvent and residual fractions of the extract was carried out according to the standard methods. Chemical constituents of the crude aqueous extract of the fresh leaves were found to be tannins, ...

  18. Preliminary study on chicken feather protein-based wood adhesives

    Science.gov (United States)

    Zehui Jiang; Daochun Qin; Chung-Yun Hse; Monlin Kuo; Zhaohui Luo; Ge Wang; Yan Yu

    2008-01-01

    The objective of this preliminary study was to partially replace phenol in the synthesis of phenol-formaldehyde resin with feather protein. Feather protein–based resins, which contained one part feather protein and two parts phenol, were formulated under the conditions of two feather protein hydrolysis methods (with and without presence of phenol during...

  19. 37 CFR 1.484 - Conduct of international preliminary examination.

    Science.gov (United States)

    2010-07-01

    ... language other than English, the United States International Preliminary Examining Authority may, where the... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Conduct of international... TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing...

  20. Preliminary investigations into the impact of an ergonomics ...

    African Journals Online (AJOL)

    The garment manufacturing process involves tasks such as fabric laying, pattern making, cutting, stitching, checking, ironing and packing. A preliminary ergonomics evaluation of the checking section indicated that the workers in this section experienced postural discomfort. A work-station was designed considering factors ...

  1. Preliminary assessment of the contamination of the marine water ...

    African Journals Online (AJOL)

    Facing the problem of the pollution of the watery ecosystems world-wide, a preliminary assessment of the contamination of marine environment was performed on samples of water and fish coming from the Atlantic Ocean on the coasts of Cotonou. Aluminium (Al), cadmium (Cd), chromium (Cr), copper (Cu) and lead (Pb) ...

  2. Preliminary comparison of different reduction methods of graphene

    Indian Academy of Sciences (India)

    ... (XPS) and four-point probe conductivity measurement. Understanding the different characteristics of different RGO by preliminary comparison is helpful in tailoring the characteristics of graphene materials for diverse applications and developing a simple, green, and efficient method for the mass production of graphene.

  3. Preliminary concepts for detecting national diversion of LWR spent fuel

    International Nuclear Information System (INIS)

    Sonnier, C.S.; Cravens, M.N.

    1978-04-01

    Preliminary concepts for detecting national diversion of LWR spent fuel during storage, handling and transportation are presented. Principal emphasis is placed on means to achieve timely detection by an international authority. This work was sponsored by the Department of Energy/Office of Safeguards and Security (DOE/OSS) as part of the overall Sandia Fixed Facility Physical Protection Program

  4. Practical Recommendations for the Preliminary Design Analysis of ...

    African Journals Online (AJOL)

    Interior-to-exterior shear ratios for equal and unequal bay frames, as well as column inflection points were obtained to serve as practical aids for preliminary analysis/design of fixed-feet multistory sway frames. Equal and unequal bay five story frames were analysed to show the validity of the recommended design ...

  5. Preliminary Study of Plants Used in Ethnoveterinary Medicine in ...

    African Journals Online (AJOL)

    Preliminary Study of Plants Used in Ethnoveterinary Medicine in Tunisia and in Italy. ... African Journal of Traditional, Complementary and Alternative Medicines ... Results: Thirty-nine plants, representing 22 families, used in Tunisia in ethnoveterinary medicine were reported, and comparisons made with close species used ...

  6. Preliminary trial of fertilizer types on pineapple ( Ananas Cosmosus ...

    African Journals Online (AJOL)

    Preliminary trial of fertilizer types on pineapple (Ananas Cosmosus grown in coastal acid sands of Cross River State, Nigeria. W Ubi, H Igwe, S Ekpe, Otu Ibor. Abstract. No Abstract. Global Journal of Pure and Applied Sciences Vol. 11(4) 2005: 457-460. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL ...

  7. A Preliminary Appraisal Of The Composition And Industrial ...

    African Journals Online (AJOL)

    A preliminary appraisal of the composition and geotechnical properties of clay deposits at Tumfure, Rukwu and Tashar Garba in Udubo area, northeastern Nigeria has been undertaken and results related to their industrial suitability. Mineralogical studies indicate that the clay is mainly kaolinitic while quartz and feldspar are ...

  8. Photorealistic avatar and teen physical activity: Feasibility and preliminary efficacy

    Science.gov (United States)

    Exergames played with a photorealistic avatar may enhance motivation to play, as well as frequency, duration, and intensity of game-play. This manuscript reports the feasibility and preliminary efficacy of an exergame played with a photorealistic avatar on physical activity intensity in a laboratory...

  9. Preliminary results of neutron production in Sahand plasma focus device

    International Nuclear Information System (INIS)

    Siahpoush, V.; Mohammadi, M.A.; Khorram, S.; Shabani, I.; Borhanian, J.; Ashrafi, S.; Naghshara, H.; Moslehi-Fard, M.; Sobhanian, S.

    2004-01-01

    We report in this paper the preliminary results of neutron generation during fusion reaction in deuterium in the Sahand Filipov type plasma focus, recently installed and put in operation at Tabriz University. The special calibration procedure for neutron detection system, using activation method is described

  10. Preliminary Investigation of Kaduna-Grown Cashew Nutshell Liquid ...

    African Journals Online (AJOL)

    Preliminary Investigation of Kaduna-Grown Cashew Nutshell Liquid as a Natural Precursor for Dyestuffs, Pigments and Binders for Leather Finishing. ... The results show that CNSL from the Kaduna-grown cashew nuts is a semi-drying oil and suitable for the synthesis of resins and dyestuff intermediates. It, therefore, has a ...

  11. Research note A preliminary study of sexual reproduction in ...

    African Journals Online (AJOL)

    Research note. A preliminary study of sexual reproduction in Portulacaria afra. HM Venter, MM Wolfson, P Avenant. Abstract. The sexual reproductive system of Portulacaria afra is characterized by the occurrence of gynodioecy; hermaphrodite and female plants occur in approximately equal proportions in all the populations ...

  12. Preliminary annual estimates of regional nitrate supply in the ...

    African Journals Online (AJOL)

    First-order estimates of annual potential new production are presented for the southern Benguela upwelling region for the decade of the 1980s. Using satellite images of sea surface temperature and a 10-year record of sea level, preliminary estimates of potential new production for 12-month periods between May and June ...

  13. Collateral Information for Equating in Small Samples: A Preliminary Investigation

    Science.gov (United States)

    Kim, Sooyeon; Livingston, Samuel A.; Lewis, Charles

    2011-01-01

    This article describes a preliminary investigation of an empirical Bayes (EB) procedure for using collateral information to improve equating of scores on test forms taken by small numbers of examinees. Resampling studies were done on two different forms of the same test. In each study, EB and non-EB versions of two equating methods--chained linear…

  14. Preliminary Results on Polypropylene Mesh Use for Abdominal ...

    African Journals Online (AJOL)

    Background: Incisional hernia is a major surgical problem. Several methods of hernia repair have been described but their outcome has been disappointing. This preliminary retrospective study reports on our experience with polypropylene mesh repair. Methods: The technique of mesh placement on anterior rectus ...

  15. Preliminary study and Identification of insects' species of forensic ...

    African Journals Online (AJOL)

    The proper identification of the insect and arthropod species of forensic importance is the most crucial element in the field of forensic entomology. The main objective in this study was the identification of insects' species of forensic importance in Urmia (37°, 33 N. and 45°, 4, 45 E.) and establishment of a preliminary ...

  16. Preliminary Study on the Effect of Halofantrine Hydrochloride on the ...

    African Journals Online (AJOL)

    Preliminary Study on the Effect of Halofantrine Hydrochloride on the Testes of Mature Wistar Rats. ... Fifteen male adult rats of Wistar strain (Rattus Norvegicus) weighing between 200-300g were divided into three groups of five rats each were used for the study. The first group (Group A) was given 0. 05ml of drug/100g of ...

  17. Preliminary Results of High-Energy Cosmic Ray Muons as ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Astrophysics and Astronomy; Volume 38; Issue 1. Preliminary Results of High-Energy Cosmic Ray Muons as Observed by a Small Multiwire Detector Operated at High Cutoff Rigidity. Abdullrahnan Maghrabi Mohammed Alanazi A. Aldosari M. Almuteri. Research Article Volume 38 Issue 1 March ...

  18. Preliminary design report for the prototypical fuel rod consolidation system

    International Nuclear Information System (INIS)

    Rosa, J.M.

    1986-01-01

    This report documents NUTECH's preliminary design of a dry, spent fuel rod consolidation system. This preliminary design is the result of Phase I of a planned four phase project. The present report on this project provides a considerable amount of detail for a preliminary design effort. The design and all of its details are described in this Preliminary Design Report (PDR). The NUTECH dry rod consolidation system described herein is remotely operated. It provides for automatic operation, but with operator hold points between key steps in the process. The operator has the ability to switch to a manual operation mode at any point in the process. The system is directed by the operator using an executive computer which controls and coordinates the operation of the in-cell equipment. The operator monitors the process using an in-cell closed circuit television (CCTV) system with audio output and equipment status displays on the computer monitor. The in-cell mechanical equipment consists of the following: (1) two overhead cranes with manipulators; (2) a multi-degree of freedom fuel handling table and its clamping equipment; (3) a fuel assembly end fitting removal station and its tools; (4) a consolidator (which pulls rods, assembles the consolidated bundle and loads the canister); (5) a canister end cap welder and weld inspection system; (6) decontamination systems; and (7) the CCTV and microphone systems

  19. A preliminary investigation of remifentanil as a labor analgesic.

    Science.gov (United States)

    Olufolabi, A J; Booth, J V; Wakeling, H G; Glass, P S; Penning, D H; Reynolds, J D

    2000-09-01

    In this preliminary investigation, we evaluated the safety and analgesic efficacy of IV remifentanil for labor pain. Four women were studied, and then the trial was terminated because administration of this novel synthetic opioid produced significant maternal side effects in the absence of effective pain control.

  20. A preliminary assessment of the potential risks from electrical ...

    African Journals Online (AJOL)

    ... Grey-crowned Crane Balearica regulorum, Lesser Flamingo Phoeniconaias minor, White-backed Vulture Gyps africanus, Rüppell's Vulture Gyps rueppellii, Martial Eagle Polemaetus bellicosus, White Stork Ciconia ciconia, Secretarybird Sagittarius serpentarius, and various sit-and-wait raptors. These preliminary findings ...