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Sample records for amgdala preliminary evidence

  1. The Communicative Effectiveness Survey: Preliminary Evidence of Construct Validity

    Science.gov (United States)

    Donovan, Neila J.; Kendall, Diane L.; Young, Mary Ellen; Rosenbek, John C.

    2008-01-01

    Purpose: To provide preliminary evidence of the construct validity of the Communicative Effectiveness Survey (CES) for individuals with dysarthria and idiopathic Parkinson's disease (PD). Method: In a prospective, quasi-experimental design, 25 participants each were assigned to 3 groups (N = 75): PD and dysarthria, non-PD and no dysarthria, and PD…

  2. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    Directory of Open Access Journals (Sweden)

    1Maryam Kazemi

    2013-11-01

    Full Text Available Each year, over a billion Muslims fast worldwide during the month of Ramadan. Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to the persistent gap between current expert knowledge and conclusive, strong evidence regarding the pathophysiologic and metabolic alterations by fasting, and the consensus that healthcare professionals should reach, in order to manage various patient groups during this month. In this review, we summarize the results of our initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition. We also go through the important clinical results of patients who have had previous history of cardiovascular disease, type 2 diabetes, asthma and renal colic. Our studies have presented some evidence in favor of Ramadan fasting and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. We attempt to present some relevant evidence clarify future scopes in this area of study, and provide suggestions for future investigations.

  3. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    Directory of Open Access Journals (Sweden)

    Maryam Kazemi

    2013-12-01

    Full Text Available Each year, over a billion Muslims fast worldwide during the month of Ramadan.  Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to the persistent gap between current expert knowledge and conclusive, strong evidence regarding the pathophysiologic and metabolic alterations by fasting, and the consensus that healthcare professionals should reach, in order to manage various patient groups during this month. In this review, we summarize the results of our initial studies regarding the effects of Ramadan fasting on some clinical conditions including alterations of body composition. We also go through the important clinical results of patients who have had previous history of cardiovascular disease, type 2 diabetes, asthma and renal colic. Our studies have presented some evidence in favor of Ramadan fasting and encourage those with mentioned diseases to consult their physicians and follow medical and scientific recommendations. We attempt to present some relevant evidence clarify future scopes in this area of study, and provide suggestions for future investigations.

  4. Ramadan fasting: Evidence or expert opinion? Results of preliminary studies

    OpenAIRE

    Maryam Kazemi; Mohsen Nematy; Abdolreza Norouzy; Maral Amini; Seyed Amirreza Mohajeri; Amirreza Razavi

    2013-01-01

    Each year, over a billion Muslims fast worldwide during the month of Ramadan. Through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. Conversely, the available evidence regarding the health benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many of them fast conceivably and their clinical condition is prone to deteriorate. This is due to t...

  5. Deep Brain Stimulation in Huntington’s Disease—Preliminary Evidence on Pathophysiology, Efficacy and Safety

    Directory of Open Access Journals (Sweden)

    Lars Wojtecki

    2016-08-01

    Full Text Available Huntington’s disease (HD is one of the most disabling degenerative movement disorders, as it not only affects the motor system but also leads to cognitive disabilities and psychiatric symptoms. Deep brain stimulation (DBS of the pallidum is a promising symptomatic treatment targeting the core motor symptom: chorea. This article gives an overview of preliminary evidence on pathophysiology, safety and efficacy of DBS in HD.

  6. Size, Diversification and Risk: Preliminary Evidence from Commercial Banks in Pakistan

    OpenAIRE

    Ayesha Afzal; Nawazish Mirza

    2012-01-01

    The aim of this paper is to provide some preliminary evidence on relation between size, diversification and risk in commercial banks of Pakistan. Using a panel of Pakistani banks, we investigated whether bigger banks are better diversified than smaller banks.The results suggested that larger banks were more diversified than their smaller counterparts mainly on account of their outreach and size of credit portfolio. On the risk side, based on accounting and market based risk measures, we explo...

  7. Size, Diversification and Risk: Preliminary Evidence from Commercial Banks in Pakistan

    Directory of Open Access Journals (Sweden)

    Ayesha Afzal

    2012-12-01

    Full Text Available The aim of this paper is to provide some preliminary evidence on relation between size, diversification and risk in commercial banks of Pakistan. Using a panel of Pakistani banks, we investigated whether bigger banks are better diversified than smaller banks.The results suggested that larger banks were more diversified than their smaller counterparts mainly on account of their outreach and size of credit portfolio. On the risk side, based on accounting and market based risk measures, we explored if there is any impact of diversification on risk. We could not deduce significant result in favor of accounting risk measure of impaired lending signaling that banks find no incentive in diversification of credit books. The market based measures of VaR and Default indicator were significantly related to diversification signifying that market participants consider diversification as a relevant tool for risk mitigation. These findings have policy implications for regulators and risk management to ensure stability in financial system.

  8. The Influence of Sleep on the Consolidation of Positive Emotional Memories: Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Alexis M. Chambers

    2014-05-01

    Full Text Available Studies have not only shown that a period of sleep following learning offers greater benefits to later memory than a period of wakefulness, but also that sleep actively promotes those components of memories that are emotionally salient. However, sleep's role in emotional memory consolidation has largely been investigated with memories that are specifically negative in content, such as memory for negative images or texts, leaving open the question of whether sleep influences positive memories in a similar manner. The current study investigated the emotional memory trade-off effect for positive versus neutral information. Scenes in which a positive or neutral object was placed on a neutral background were encoded prior to a period of polysomnographically-monitored nocturnal sleep or daytime wakefulness. Recognition memory was tested for the objects and backgrounds separately following the delay using the Remember/Know paradigm. Compared to wake participants, those who slept during the delay had increased recollection memory performance for positive objects, but not the neutral components of the studied scenes. Further, familiarity of positive objects was negatively correlated with REM latency. These results provide preliminary evidence that sleep contributes to the selective processing of positive memories, and point toward a role for REM sleep in positive memory formation.

  9. Reliability and preliminary evidence of validity of a Farsi version of the depression anxiety stress scales.

    Science.gov (United States)

    Bayani, Ali Asghar

    2010-08-01

    The internal consistency, test-retest reliability, and construct validity of the Farsi version of the Depression Anxiety Stress Scales were examined, with a sample of 306 undergraduate students (123 men, 183 women) ranging from 18 to 51 years of age (M age = 25.4, SD = 6.1). Participants completed the Satisfaction with Life Scale, Rosenberg Self-esteem Scale, and the Depression Anxiety Stress Scales. The findings confirmed the preliminary reliabilities and preliminary construct validity of the Farsi translation of the Depression Anxiety Stress Scales. PMID:21058592

  10. Safety and evidence concept. Report on the work package 4. Preliminary safety analysis for the site Gorleben

    International Nuclear Information System (INIS)

    The national legal regulations including the German atomic law, the radiation protection law and the federal mining law define the general framework conditions for the final disposal of radioactive waste. In addition the safety requirements concerning heat generating radioactive wastes are of importance. The project VSG (preliminary safety analysis for the site Gorleben) is aimed to the safety of the installation following the closure phase of the repository. The safety concept discusses the legal requirement, the evidence concept is concerned with the demonstration of the efficacy of the safety concept with respect to the safe enclosure of radionuclides and the assessment of long-term safety based on model calculations.

  11. Violence against children:preliminary evidence from Colombia, El Salvador, Cambodia and Ecuador.

    OpenAIRE

    Blanco, F.; M. G. Breglia; L.Guarcello; Valdivia, C

    2008-01-01

    The issue of child abuse in developing countries is of utmost importance for designing policies directed to vulnerable children and aimed at combating the worst forms of child labour. Unfortunately there is limited empirical basis for formulating policies and programmes addressing violence against children in developing countries. This preliminary study uses data from El Salvador(SIMPOC 2001), Colombia (SIMPOC 2001), Cambodia (SIMPOC, 2001) and Ecuador (SIMPOC, 2001) and constitutes a startin...

  12. Transport processes for Chernobyl-labelled sediments: preliminary evidence from upland mid-Wales

    International Nuclear Information System (INIS)

    The nuclear accident at Chernobyl in April 1986 resulted in a significant increase in the inventory of radiocaesium retained in the soil in many regions of the United Kingdom. The deposition of 134Cs provides a convenient tool for the examination of erosional processes in upland systems. Detailed soil sampling has been undertaken within the Plynlimon experimental catchments to establish the pattern of deposition of Chernobyl-derived radionuclides. The preliminary results of a combined radiometric and mineral magnetic approach to the study of the transport of Chernobyl-labelled sediments and their source areas on these upland catchments in mid-Wales are described. (author)

  13. The Effects of Tax Rules on Nonresidential Fixed Investment: Some Preliminary Evidence from the 1980s

    OpenAIRE

    Martin Feldstein; Joosung Jun

    1986-01-01

    The evidence presented in this study confirms that tax-induced changes in the profitability of investment have had a powerful effect on the share of GNP devoted to nonresidential fixed investment. More specifically, we have reestimated two models of aggregate investment initially presented in Feldstein, "Inflation, Tax Rules and Investment: Some Econometric Evidence,"(Econometrica, 1982). The present study extends the previous analysis byusing revised national income accounts, by improving th...

  14. Symptom Cluster and Quality of Life: Preliminary Evidence in Multiple Sclerosis

    Science.gov (United States)

    Motl, Robert W.; McAuley, Edward

    2010-01-01

    The present study examined the symptom cluster of fatigue, pain, and depression as a correlate of reduced quality of life (QOL) in individuals with multiple sclerosis (MS). The sample included 291 individuals with a definite diagnosis of MS who were enrolled in a 6-month longitudinal study of physical activity and QOL. The participants completed baseline measures of fatigue, depression, and pain and follow-up measures of QOL. Cluster analysis initially identified three sub-groups differing in experiences of fatigue, depression, and pain, and analysis of variance then indicated that the three sub-groups differed in QOL. The sub-group with lowest scores on all three symptoms had the highest QOL, whereas the sub-group with the highest scores on the symptoms had the worst QOL. Such findings provide preliminary support for fatigue, pain, and depression as a symptom cluster that correlates with reduced QOL in persons with MS. PMID:20804116

  15. Preliminary Evidence for Associations of CHRM2 with Substance Use and Disinhibition in Adolescence

    OpenAIRE

    Hendershot, Christian S.; Bryan, Angela D.; Feldstein Ewing, Sarah W.; Claus, Eric D; Hutchison, Kent E.

    2011-01-01

    Evidence for shared heritable influences across domains of substance use suggests that some genetic variants influence broad risk for externalizing behaviors. Theories of externalizing psychopathology also suggest that genetic liability for substance use manifests as temperamental risk factors, particularly those related to behavioral disinhibition, during adolescence. The cholinergic muscarinic receptor 2 gene (CHRM2) is a promising candidate for studying genetic influences on broad-based ri...

  16. Recruiting for values in healthcare: a preliminary review of the evidence

    OpenAIRE

    Patterson, F.; Prescott-Clements, L.; Zibarras, L. D.; Edwards, H.; Kerrin, M.; Cousans, F.

    2015-01-01

    Displaying compassion, benevolence and respect, and preserving the dignity of patients are important for any healthcare professional to ensure the provision of high quality care and patient outcomes. This paper presents a structured search and thematic review of the research evidence relating to values-based recruitment within healthcare. Several different databases, journals and government reports were searched to retrieve studies relating to values-based recruitment published between 1998 a...

  17. Knowledge of evidence-based dentistry among academic dental practitioners of Bhopal, India: a preliminary survey

    Directory of Open Access Journals (Sweden)

    Aishwarya Singh

    2015-06-01

    Full Text Available This study aimed to characterize the knowledge of evidence-based dentistry (EBD among dental faculty members in the city of Bhopal in central India. A cross-sectional questionnaire was administered at two dental colleges in Bhopal City. All dental faculty members who were present on the day of the study and who agreed to participate were included in the study. A total of 50 dental faculty members returned the questionnaire. Six Likert-type questions were asked, and the percentages of various responses were used for analysis. Sixteen faculty members (32.0% strongly agreed that EBD is a process of making decisions based on scientifically proven evidence. Fifteen faculty members (30.0% strongly disagreed or disagreed with the item stating that the best and quickest way to find evidence is by reading textbooks or asking experienced colleagues. Thirteen faculty members (26.0% strongly agreed that EBD allows dentists to improve their scientific knowledge and clinical skills. It is recommended that EBD be included in undergraduate and postgraduate curricula and in intensive continuing dental education programs that are conducted for dental faculty members.

  18. Preliminary evidence of reduced cognitive inhibition in methamphetamine-dependent individuals.

    Science.gov (United States)

    Salo, Ruth; Nordahl, Thomas E; Possin, Kate; Leamon, Martin; Gibson, David R; Galloway, Gantt P; Flynn, Neil M; Henik, Avishai; Pfefferbaum, Adolf; Sullivan, Edith V

    2002-08-01

    Chronic methamphetamine abuse is associated with disruption of frontostriatal function involving serotonin and dopamine circuitry. Clinically, methamphetamine-dependent (MD) individuals are highly distractible and have difficulty focussing. Here, we used a computerized single-trial version of the Stroop Test to examine selective attention and priming in MD. Subject groups comprised eight MD men (31.7+/-7.2 years of age), who had used methamphetamine for 15.75+/-8.4 years but were currently abstinent for 2-4 months, and 12 controls (35.7+9.7 years of age). Compared with the control group, the MD group exhibited significantly greater interference (P<0.05) despite intact priming. Error rates did not differ between the groups. This preliminary finding of reduced cognitive inhibition in MD individuals is consistent with the distractibility they show clinically. Furthermore, the dissociation between explicit attentional performance and priming effects suggests that some attentional functions are not as affected by long-term methamphetamine use as others. PMID:12140121

  19. Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Maya Weinstein

    2015-01-01

    Full Text Available Neuroplasticity studies examining children with hemiparesis (CH have focused predominantly on unilateral interventions. CH also have bimanual coordination impairments with bimanual interventions showing benefits. We explored neuroplasticity following hand-arm bimanual intensive therapy (HABIT of 60 hours in twelve CH (6 females, mean age 11 ± 3.6 y. Serial behavioral evaluations and MR imaging including diffusion tensor (DTI and functional (fMRI imaging were performed before, immediately after, and at 6-week follow-up. Manual skills were assessed repeatedly with the Assisting Hand Assessment, Children’s Hand Experience Questionnaire, and Jebsen-Taylor Test of Hand Function. Beta values, indicating the level of activation, and lateralization index (LI, indicating the pattern of brain activation, were computed from fMRI. White matter integrity of major fibers was assessed using DTI. 11/12 children showed improvement after intervention in at least one measure, with 8/12 improving on two or more tests. Changes were retained in 6/8 children at follow-up. Beta activation in the affected hemisphere increased at follow-up, and LI increased both after intervention and at follow-up. Correlations between LI and motor function emerged after intervention. Increased white matter integrity was detected in the corpus callosum and corticospinal tract after intervention in about half of the participants. Results provide first evidence for neuroplasticity changes following bimanual intervention in CH.

  20. Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence

    Science.gov (United States)

    Weinstein, Maya; Myers, Vicki; Green, Dido; Schertz, Mitchell; Shiran, Shelly I.; Geva, Ronny; Artzi, Moran; Gordon, Andrew M.; Fattal-Valevski, Aviva; Ben Bashat, Dafna

    2015-01-01

    Neuroplasticity studies examining children with hemiparesis (CH) have focused predominantly on unilateral interventions. CH also have bimanual coordination impairments with bimanual interventions showing benefits. We explored neuroplasticity following hand-arm bimanual intensive therapy (HABIT) of 60 hours in twelve CH (6 females, mean age 11 ± 3.6 y). Serial behavioral evaluations and MR imaging including diffusion tensor (DTI) and functional (fMRI) imaging were performed before, immediately after, and at 6-week follow-up. Manual skills were assessed repeatedly with the Assisting Hand Assessment, Children's Hand Experience Questionnaire, and Jebsen-Taylor Test of Hand Function. Beta values, indicating the level of activation, and lateralization index (LI), indicating the pattern of brain activation, were computed from fMRI. White matter integrity of major fibers was assessed using DTI. 11/12 children showed improvement after intervention in at least one measure, with 8/12 improving on two or more tests. Changes were retained in 6/8 children at follow-up. Beta activation in the affected hemisphere increased at follow-up, and LI increased both after intervention and at follow-up. Correlations between LI and motor function emerged after intervention. Increased white matter integrity was detected in the corpus callosum and corticospinal tract after intervention in about half of the participants. Results provide first evidence for neuroplasticity changes following bimanual intervention in CH. PMID:26640717

  1. Preliminary evidence for human globus pallidus pars interna neurons signaling reward and sensory stimuli.

    Science.gov (United States)

    Howell, Nicholas A; Prescott, Ian A; Lozano, Andres M; Hodaie, Mojgan; Voon, Valerie; Hutchison, William D

    2016-07-22

    The globus pallidus pars interna (GPi) is a component of the basal ganglia, a network of subcortical nuclei that process motor, associative, and limbic information. While non-human primate studies have suggested a role for the GPi in non-motor functions, there have been no single-unit studies of non-motor electrophysiological behavior of human GPi neurons. We therefore sought to extend these findings by collecting single-unit recordings from awake patients during functional stereotactic neurosurgery targeting the GPi for deep brain stimulation. To assess cellular responses to non-motor information, patients performed a reward task where virtual money could be won, lost, or neither, depending on their performance while cellular activity was monitored. Changes in the firing rates of isolated GPi neurons after the presentation of reward-related stimuli were compared between different reward contingencies (win, loss, null). We observed neurons that modulated their firing rate significantly to the presentation of reward-related stimuli. We furthermore found neurons that responded to visual-stimuli more broadly. This is the first single-unit evidence of human GPi neurons carrying non-motor information. These results are broadly consistent with previous findings in the animal literature and suggest non-motor information may be represented in the single-unit activity of human GPi neurons. PMID:27109924

  2. Preliminary evidence for human fecal contamination in corals of the Florida Keys, USA.

    Science.gov (United States)

    Lipp, Erin K; Jarrell, Jennifer L; Griffin, Dale W; Lukasik, Jerzy; Jacukiewicz, Jennifer; Rose, Joan B

    2002-07-01

    Corals and reef environments are under increased stress from anthropogenic activities, particularly those in the vicinity of heavily populated areas such as the Florida Keys. The potential adverse impacts of wastewater can affect both the environment and human health; however, because of the high decay rate of bacterial indicators in coral reef waters it has been difficult to document the presence of microbial contaminants and to assign risks in these environments. Here we show initial evidence that microorganisms associated with human feces are concentrated along the surface of coral heads relative to the overlying water column in the Florida Keys. Bacterial indicators (fecal coliform bacteria, enterococci or Clostridium perfringens) were detected in 66.7% of the coral surface microlayer (CSM) samples at levels between five and 1000 CFU/100 ml, but were found infrequently and at low numbers in the overlying water column ( coral mucus may accumulate enteric microorganisms in reef environments, and may indicate a risk to public and environmental health despite low indicator levels in the surrounding water. PMID:12222890

  3. Recruiting for values in healthcare: a preliminary review of the evidence.

    Science.gov (United States)

    Patterson, Fiona; Prescott-Clements, Linda; Zibarras, Lara; Edwards, Helena; Kerrin, Maire; Cousans, Fran

    2016-10-01

    Displaying compassion, benevolence and respect, and preserving the dignity of patients are important for any healthcare professional to ensure the provision of high quality care and patient outcomes. This paper presents a structured search and thematic review of the research evidence relating to values-based recruitment within healthcare. Several different databases, journals and government reports were searched to retrieve studies relating to values-based recruitment published between 1998 and 2013, both in healthcare settings and other occupational contexts. There is limited published research related to values-based recruitment directly, so the available theoretical context of values is explored alongside an analysis of the impact of value congruence. The implications for the design of selection methods to measure values is explored beyond the scope of the initial literature search. Research suggests some selection methods may be appropriate for values-based recruitment, such as situational judgment tests (SJTs), structured interviews and multiple-mini interviews (MMIs). Personality tests were also identified as having the potential to compliment other methods (e.g. structured interviews), as part of a values-based recruitment agenda. Methods including personal statements, references and unstructured/'traditional' interviews were identified as inappropriate for values-based recruitment. Practical implications are discussed in the context of values-based recruitment in the healthcare context. Theoretical implications of our findings imply that prosocial implicit trait policies, which could be measured by selection tools such as SJTs and MMIs, may be linked to individuals' values via the behaviours individuals consider to be effective in given situations. Further research is required to state this conclusively however, and methods for values-based recruitment represent an exciting and relatively unchartered territory for further research. PMID:25616718

  4. Preliminary evidence for obesity-associated insulin resistance in adolescents without elevations of inflammatory cytokines

    Directory of Open Access Journals (Sweden)

    Cohen Jessica I

    2012-06-01

    Full Text Available Abstract Background To ascertain whether the associations between obesity, inflammation, and insulin resistance established in human adult studies are found among adolescents. Methods We contrasted 36 obese and 24 lean youth on fasting glucose, insulin levels, lipid profile, hemoglobin A1C, markers of hepatic function, white blood cell count, C-reactive protein (CRP and fibrinogen levels. The cytokines IL-6, TNF-α, IFN-γ, IL-10 and IL-4 and the adipokines leptin, resistin, and adiponectin were also compared between the two groups. The fasting glucose and insulin values were used to estimate the degree of insulin resistance with the homeostatic model assessment of insulin resistance (HOMA-IR. T-tests and correlations were run to examine group differences and associations between groups. In addition, regression analyses were used to ascertain whether the markers of inflammation were predictive of the degree of insulin resistance. Results Although obese adolescents had clear evidence of insulin resistance, only CRP, fibrinogen and leptin were elevated; there were no group differences in pro- or anti-inflammatory cytokines nor adiponectin and resistin. Anthropometric measures of obesity and level of insulin resistance were highly correlated to the acute phase reactants CRP and fibrinogen; however, the degree of insulin resistance was not predicted by the pro- or anti-inflammatory cytokine markers. Obese adolescents had higher white blood cell counts. In addition they had higher circulating alanine aminotransferase concentrations and lower circulating albumin and total protein than lean adolescents, possibly as a result of hepatocyte damage from fatty liver. Conclusion Unlike rodent or adult studies, we found that wide-spread systemic inflammation is not necessarily associated with insulin resistance among adolescents. This finding does not support the current paradigm that the associations between obesity and insulin resistance are, to a

  5. Treatment of spinal cord injury with intravenous immunoglobulin G: preliminary evidence and future perspectives.

    Science.gov (United States)

    Tzekou, Apostolia; Fehlings, Michael G

    2014-07-01

    Neuroinflammation plays an important role in the secondary pathophysiological mechanisms of spinal cord injury (SCI) and can exacerbate the primary trauma and thus worsen recovery. Although some aspects of the immune response are beneficial, it is thought that leukocyte recruitment and activation in the acute phase of injury results in the production of cytotoxic substances that are harmful to the nervous tissue. Therefore, suppression of excessive inflammation in the spinal cord could serve as a therapeutic strategy to attenuate tissue damage. The immunosuppressant methylprednisolone has been used in the setting of SCI, but there are complications which have attenuated the initial enthusiasm. Hence, there is interest in other immunomodulatory approaches, such as intravenous Immunoglobulin G (IVIg). Importantly, IVIg is used clinically for the treatment of several auto-immune neuropathies, such as Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy (CIPD) and Kawasaki disease, with a good safety profile. Thus, it is a promising treatment candidate for SCI. Indeed, IVIg has been shown by our team to attenuate the immune response and result in improved neurobehavioral recovery following cervical SCI in rats through a mechanism that involves the attenuation of neutrophil recruitment and reduction in the levels of cytokines and cytotoxic enzymes Nguyen et al. (J Neuroinflammation 9:224, 2012). Here we review published data in the context of relevant mechanisms of action that have been proposed for IVIg in other conditions. We hope that this discussion will trigger future research to provide supporting evidence for the efficiency and detailed mechanisms of action of this promising drug in the treatment of SCI, and to facilitate its clinical translation. PMID:24722853

  6. Seismic heating signatures in the Japan Trench subduction plate-boundary fault zone: evidence from a preliminary rock magnetic `geothermometer'

    Science.gov (United States)

    Yang, Tao; Dekkers, Mark J.; Zhang, Bo

    2016-04-01

    Frictional heating during earthquake rupture reveals important information on earthquake mechanisms and energy dissipation. The amount of annealing varies widely and is, as yet, poorly constrained. Here we use magnetic susceptibility versus temperature measurements during cycling to increasingly elevated temperatures to constrain the maximum temperature a slip zone has experienced. The case study comprises sheared clay cored from the Japan Trench subduction plate-boundary fault zone (décollement), which accommodated the large slip of the 2011 Mw 9.0 Tohoku-oki earthquake. The décollement was cored during the Integrated Ocean Drilling Program (IODP) Expedition 343, the Japan Trench Fast Drilling Project (JFAST). Heating signatures with estimated maximum temperatures ranging from ˜300 to over 500 °C are determined close to the multiple slip surfaces within the décollement. Since it is impossible to tie a specific slip surface to a certain earthquake, thermal evidence for the cumulative effect of several earthquakes is unveiled. This as yet preliminary rock magnetic `geothermometer' would be a useful tool to detect seismic heating along faults that experienced medium temperature rise, a range which is difficult to assess with other approaches.

  7. Preliminary evidence that different mechanisms underlie the anger superiority effect in children with and without Autism Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    Tomoko eIsomura

    2014-05-01

    Full Text Available Previous studies have demonstrated that angry faces capture humans’ attention more rapidly than emotionally positive faces. This phenomenon is referred to as the anger superiority effect (ASE. Despite atypical emotional processing, adults and children with Autism Spectrum Disorders (ASD have been reported to show ASE as well as typically developed (TD individuals. So far, however, few studies have clarified whether or not the mechanisms underlying ASE are the same for both TD and ASD individuals. Here, we tested how TD and ASD children process schematic emotional faces during detection by employing a recognition task in combination with a face-in-the-crowd task. Results of the face-in-the-crowd task revealed the prevalence of ASE both in TD and ASD children. However, the results of the recognition task revealed group differences: In TD children, detection of angry faces required more configural face processing and disrupted the processing of local features. In ASD children, on the other hand, it required more feature-based processing rather than configural processing. Despite the small sample sizes, these findings provide preliminary evidence that children with ASD, in contrast to TD children, show quick detection of angry faces by extracting local features in faces.

  8. Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

    Science.gov (United States)

    Gregório, Sheila P; Sallet, Paulo C; Do, Kim-Anh; Lin, E; Gattaz, Wagner F; Dias-Neto, Emmanuel

    2009-01-30

    An abnormality in neurodevelopment is one of the most robust etiologic hypotheses in schizophrenia (SZ). There is also strong evidence that genetic factors may influence abnormal neurodevelopment in the disease. The present study evaluated in SZ patients, whose brain structural data had been obtained with magnetic resonance imaging (MRI), the possible association between structural brain measures, and 32 DNA polymorphisms, located in 30 genes related to neurogenesis and brain development. DNA was extracted from peripheral blood cells of 25 patients with schizophrenia, genotyping was performed using diverse procedures, and putative associations were evaluated by standard statistical methods (using the software Statistical Package for Social Sciences - SPSS) with a modified Bonferroni adjustment. For reelin (RELN), a protease that guides neurons in the developing brain and underlies neurotransmission and synaptic plasticity in adults, an association was found for a non-synonymous polymorphism (Val997Leu) with left and right ventricular enlargement. A putative association was also found between protocadherin 12 (PCDH12), a cell adhesion molecule involved in axonal guidance and synaptic specificity, and cortical folding (asymmetry coefficient of gyrification index). Although our results are preliminary, due to the small number of individuals analyzed, such an approach could reveal new candidate genes implicated in anomalous neurodevelopment in schizophrenia. PMID:19054571

  9. Evident?

    DEFF Research Database (Denmark)

    Plant, Peter

    2012-01-01

    Quality assurance and evidence in career guidance in Europe are often seen as self-evident approaches, but particular interests lie behind......Quality assurance and evidence in career guidance in Europe are often seen as self-evident approaches, but particular interests lie behind...

  10. JPI Oceans Concerted support action deliverable 5.1 'Mapping and preliminary analysis of policy needs for evidence'

    OpenAIRE

    Redd, Thomas; Wood, Jacky; Foden, Jo; Mills, David; Bonne, Wendy

    2014-01-01

    CSA Oceans preliminary analysis of policy needs CSA Oceans has completed its preliminary analysis of policy needs. The public deliverable reports on the current status of marine and maritime policies relevant to JPI Oceans and identifies examples of science to policy mechanisms. The report uses stakeholder input to identify the needs of different policies to fulfil their objectives. One of the underlying issues is thought to be a lack of integration between marine and maritime activi...

  11. Online Activities for Enhancing Sex Education Curricula: Preliminary Evidence on the Effectiveness of the Abstinence and Contraception Education Storehouse.

    Science.gov (United States)

    Raghupathy, Shobana; Klein, Charles; Card, Josefina

    2013-01-01

    The purpose of this research was to conduct a preliminary evaluation of the Abstinence and Contraception Education Storehouse (ACES), a digital, classroom-based resource designed to supplement existing sex education curricula with highly interactive materials such as video clips, multimedia polls and quizzes, and audiovisual demonstrations. 335 students ages 14-19 were randomly assigned to an ACES-based (treatment) or a standard (control) sex education curriculum. Data were collected at the onset of the intervention and 3-months after the completion of the intervention. Preliminary results were highly encouraging, with ACES participants who were sexually initiated at baseline reporting at the 3-month follow-up significant reductions in the number of times they had sex in the past four weeks. Both sexually initiated and non-sexually initiated youth who experienced the ACES curriculum also demonstrated greater intent to abstain from the sex during the follow-up period than those in the control group. PMID:24078799

  12. Online Activities for Enhancing Sex Education Curricula: Preliminary Evidence on the Effectiveness of the Abstinence and Contraception Education Storehouse

    OpenAIRE

    Raghupathy, Shobana; Klein, Charles; Card, Josefina

    2013-01-01

    The purpose of this research was to conduct a preliminary evaluation of the Abstinence and Contraception Education Storehouse (ACES), a digital, classroom-based resource designed to supplement existing sex education curricula with highly interactive materials such as video clips, multimedia polls and quizzes, and audiovisual demonstrations. 335 students ages 14–19 were randomly assigned to an ACES–based (treatment) or a standard (control) sex education curriculum. Data were collected at the o...

  13. Early life stress and macaque amygdala hypertrophy: preliminary evidence for a role for the serotonin transporter gene

    OpenAIRE

    Jeremy D. Coplan; Hassan M. Fathy; Andrea P. Jackowski; Tang, Cheuk Y; Perera, Tarique D.; Mathew, Sanjay J.; Martinez, Jose; Abdallah, Chadi G.; Dwork, Andrew J.; Pantol, Gustavo; Carpenter, David; Gorman, Jack M.; Charles B Nemeroff; Owens, Michael J; Kaffman, Arie

    2014-01-01

    Background: Children exposed to early life stress (ELS) exhibit enlarged amygdala volume in comparison to controls. The primary goal of this study was to examine amygdala volumes in bonnet macaques subjected to maternal variable foraging demand (VFD) rearing, a well-established model of ELS. Preliminary analyses examined the interaction of ELS and the serotonin transporter gene on amygdala volume. Secondary analyses were conducted to examine the association between amygdala volume and other s...

  14. Preliminary evidence of health care provider support for naloxone prescription as overdose fatality prevention strategy in New York City

    OpenAIRE

    Coffin, Phillip O.; Fuller, Crystal; Vadnai, Liza; Blaney, Shannon; Galea, Sandro; Vlahov, David

    2003-01-01

    Preliminary research suggests that naloxone (Narcan), a short-acting opiate antagonist, could be provided by prescription or distribution to heroin users to reduce the likelihood of fatality from overdose. We conducted a random postal survey of 1.100 prescription-authorized health care providers in New York City to determine willingness to prescribe naloxone to patients at risk of an opiate overdose. Among 363 nurse practitioners, physicians, and physician assistants responding, 33,4% would c...

  15. Teacher Self-Assessment of Evidence-Based Classroom Practices: Preliminary Findings across Primary, Intermediate and Secondary Level Teachers

    Science.gov (United States)

    Borgmeier, Chris; Loman, Sheldon L.; Hara, Motoaki

    2016-01-01

    The limited implementation of evidence-based classroom practices and ways to provide effective professional development to address this challenge remain enduring concerns in education. Despite these concerns, there exists a well-established research literature on evidence-based practices for effective classroom management and instructional…

  16. Determinants and Contagion in Private Capital Flows: Preliminary Evidence from the 1970s and 1990s Determinants and Contagion in Private Capital Flows: Preliminary Evidence from the 1970s and 1990s

    Directory of Open Access Journals (Sweden)

    Rodrigo Valdés

    2002-03-01

    Full Text Available This paper studies the determinants of private capital flows to developing countries during the last two episodes of large inflows, the late 1970s-early 1980s and the 1990s. The paper also tests for contagion effects in capital flows among recipient countries, and tries to identify specific channels through which such effects can occur. It tests for neighborhood effects, trade-related effects, and for contagion based on the countries having similar macroeconomic indicators. The results show strong evidence for the first two effects during the 1990s, and indicate that the third effect varies depending on the type of capital flow. This paper studies the determinants of private capital flows to developing countries during the last two episodes of large inflows, the late 1970s-early 1980s and the 1990s. The paper also tests for contagion effects in capital flows among recipient countries, and tries to identify specific channels through which such effects can occur. It tests for neighborhood effects, trade-related effects, and for contagion based on the countries having similar macroeconomic indicators. The results show strong evidence for the first two effects during the 1990s, and indicate that the third effect varies depending on the type of capital flow.

  17. Lower prenatal vitamin D status and postpartum depressive symptomatology in African American women: Preliminary evidence for moderation by inflammatory cytokines.

    Science.gov (United States)

    Accortt, Eynav Elgavish; Schetter, Christine Dunkel; Peters, Rosalind M; Cassidy-Bushrow, Andrea E

    2016-04-01

    Vitamin D deficiency and elevated pro-inflammatory cytokines have each been associated individually with postpartum depression (PPD). African American women are at increased risk for prenatal vitamin D deficiency, inflammation, and prenatal and postpartum depressive symptoms, but biological risk factors for PPD in this population have rarely been tested. This prospective study tested whether low prenatal vitamin D status (serum 25-hydroxyvitamin D, 25[OH]D) predicted PPD symptomatology in pregnant African American women and whether high levels of prenatal inflammatory cytokines interacted with low 25(OH)D in effects on PPD symptoms. Vitamin D status was measured in the first trimester in a sample of 91 African American pregnant women who had a second trimester blood sample assayed for inflammatory markers. Depressive symptoms were assessed at a postpartum visit. An inverse association between prenatal log 25(OH)D and PPD symptomatology approached significance (β = -0.209, p = 0.058), and interleukin-6 and IL-6/IL-10 ratio significantly moderated the effect. Among women with higher levels of inflammatory markers, lower prenatal log 25(OH)D was associated with significantly higher PPD symptoms (p < 0.05). These preliminary results are intriguing because, if replicable, easy  translational opportunities, such as increasing vitamin D status in pregnant women with elevated pro-inflammatory cytokines, may reduce PPD symptoms. PMID:26407996

  18. Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr Virus

    Directory of Open Access Journals (Sweden)

    Hickie Ian B

    2006-01-01

    Full Text Available Abstract Background Acute infectious diseases are typically accompanied by non-specific symptoms including fever, malaise, irritability and somnolence that usually resolve on recovery. However, in some individuals these symptoms persist in what is commonly termed post-infective fatigue. The objective of this pilot study was to determine the gene expression correlates of post-infective fatigue following acute Epstein Barr virus (EBV infection. Methods We followed 5 people with acute mononucleosis who developed post-infective fatigue of more than 6 months duration and 5 HLA-matched control subjects who recovered within 3 months. Subjects had peripheral blood mononuclear cell (PBMC samples collected at varying time points including at diagnosis, then every 2 weeks for 3 months, then every 3 months for a year. Total RNA was extracted from the PBMC samples and hybridized to microarrays spotted with 3,800 oligonucleotides. Results Those who developed post-infective fatigue had gene expression profiles indicative of an altered host response during acute mononucleosis compared to those who recovered uneventfully. Several genes including ISG20 (interferon stimulated gene, DNAJB2 (DnaJ [Hsp40] homolog and CD99, CDK8 (cyclin-dependent kinase 8, E2F2 (E2F transcription factor 2, CDK8 (cyclin-dependent kinase 8, and ACTN2 (actinin, alpha 2, known to be regulated during EBV infection, were differentially expressed in post-infective fatigue cases. Several of the differentially expressed genes affect mitochondrial functions including fatty acid metabolism and the cell cycle. Conclusion These preliminary data provide insights into alterations in gene transcripts associated with the varied clinical outcomes from acute infectious mononucleosis.

  19. Early Life Stress and Macaque Amygdala Hypertrophy: Preliminary Evidence for a Role for the Serotonin Transporter Gene.

    Directory of Open Access Journals (Sweden)

    Jeremy D Coplan

    2014-10-01

    Full Text Available Background: Children exposed to early life stress (ELS exhibit enlarged amygdala volume in comparison to controls. The primary goal of this study was to examine amygdala volumes in bonnet macaques subjected to maternal variable foraging demand (VFD rearing, a well-established model of ELS. Preliminary analyses examined the interaction of ELS and the serotonin transporter gene on amygdala volume. Secondary analyses were conducted to examine the association between amygdala volume and other stress-related variables previously found to distinguish VFD and non-VFD reared animals. Methods: Twelve VFD-reared and nine normally reared monkeys completed MRI scans on a 3T system (mean age=5.2 years. Results: Left amygdala volume was larger in VFD versus control macaques. Larger amygdala volume was associated with: high cerebrospinal fluid concentrations of corticotropin releasing-factor (CRF determined when the animals were in adolescence (mean age=2.7 years; reduced fractional anisotropy of the anterior limb of the internal capsule during young adulthood (mean age=5.2 years and timid anxiety-like responses to an intruder during full adulthood (mean age=8.4 years. Right amygdala volume varied inversely with left hippocampal neurogenesis assessed in late adulthood (mean age=8.7 years. Exploratory analyses also showed a gene-by-environment effect, with VFD-reared macaques with a single short allele of the serotonin transporter gene exhibiting larger amygdala volume compared to VFD-reared subjects with only the long allele and normally reared controls. Conclusion: These data suggest that the left amygdala exhibits hypertrophy after ELS, particularly in association with the serotonin transporter gene, and that amygdala volume variation occurs in concert with other key stress-related behavioral and neurobiological parameters observed across the lifecycle. Future research is required to understand the mechanisms underlying these diverse and persistent changes a

  20. Serum Lp(a) in diabetics with and without evidence of clinical nephropathy—A preliminary study

    OpenAIRE

    Kumari, S. Jaya; Jayaram, Nivedita; Vincent, Lloyd; Venkatesh, T.

    2002-01-01

    Type 2 diabetes is associated with a marked increase in the risk of coronary artery disease. Dyslipidaemia is believed to be a major cause of this increased risk. Recently, elevated levels of lipoprotein (a), Lp(a), have been reported to be associated with an increased risk. However there is very little data regarding Lp(a) concentrations and type 2 diabetes from India. The objective of the study was to assess serum Lp(a) levels in type 2 diabetics with and with out evidence of clinical nephr...

  1. Promoting Mentalizing in Pupils by Acting on Teachers: Preliminary Italian Evidence of the “Thought in Mind” Project

    Science.gov (United States)

    Valle, Annalisa; Massaro, Davide; Castelli, Ilaria; Sangiuliano Intra, Francesca; Lombardi, Elisabetta; Bracaglia, Edoardo; Marchetti, Antonella

    2016-01-01

    Mentalization research focuses on different aspects of this topic, highlighting individual differences in mentalizing and proposing programs of intervention for children and adults to increase this ability. The “Thought in Mind Project” (TiM Project) provides training targeted to adults—teachers or parents—to increase their mentalization and, consequently, to obtain mentalization improvement in children. The present research aimed to explore for the first time ever the potential of training for teachers based on the TiM Project, regarding the enhancement of mentalizing of an adult who would have interacted as a teacher with children. For this reason, two teachers – similar for meta-cognitive and meta-emotional skills - and their classes (N = 46) were randomly assigned to the training or control condition. In the first case, the teacher participated in training on the implementation of promotion of mentalizing in everyday school teaching strategies; in the second case the teacher participated in a control activity, similar to training for scheduling and methods, but without promoting the implementation of mentalization (in both conditions two meetings lasting about 3 h at the beginning of the school year and two supervisions during the school year were conducted). The children were tested by tasks assessing several aspects of mentalization (second and third-order false belief understanding, Strange Stories, Reading the mind in the Eyes, Mentalizing Task) both before and after the teacher participate in the TiM or control training (i.e., at the beginning and at the end of the school year). The results showed that, although some measured components of mentalization progressed over time, only the TiM Project training group significantly improved in third order false belief understanding and changed - in a greater way compared to the control group – in two of the three components of the Mentalizing Task. These evidences are promising about the idea that the

  2. Forming Entrepreneurial Mindsets? Preliminary Evidence of Teaching Practices from Primary Schools in a Developing Area in South America

    Directory of Open Access Journals (Sweden)

    Maria Auxiliadora N. Figueiredo-Nery

    2008-08-01

    Full Text Available Over the past few years there has been a renewed interest by governments, companies and academics in the role of entrepreneurship in innovation and economic growth. There has also been a proliferation of studies on education for entrepreneurship in industrialised and developing countries. However, by addressing ‘entrepreneurship’ in terms of SMEs and high-tech start-ups, they overlook: (i the blurring distinctions between entrepreneurial and managerial capitalism, (ii an erosion of the Schumpeterian dichotomy between large and small firms, and (iii the growing importance of entrepreneurial management within companies as a source for economic growth. Additionally, ‘entrepreneurship’ tends to be taught as a stand-alone topic in higher education and business/non-business courses. Empirical studies related to entrepreneurship education within primary schools, especially in least developed locations in developing countries, are largely missing in this field. Drawing on first-hand empirical evidence from primary schools in a developing area in South America, this paper examines the incidence and functioning of pedagogic practices potentially related to the initial formation of entrepreneurial mindsets. The findings show that, despite some efforts, the researched schools suffered from, not surprisingly, inadequate physical conditions and, most importantly, teachers’ unawareness and deficient qualification related to the adoption of these techniques. These problems seemed to prevent children from developing important features of their initial entrepreneurial mindsets. Thus, if companies and countries want to secure their sources of revolutionary ideas and continuous and des-continuous innovation, they need to have a long-term commitment to continuously develop and nurture the seeds for their future innovative knowledge bases. Specifically, a comprehensive, long-term, geographically and socially inclusive perspective on entrepreneurship

  3. Preliminary Starch Grain Evidence of Ancient Stone Tool Use at the Early Archaic (9,000 B.P. Site of Sandy Hill, Mashantucket, Connecticut

    Directory of Open Access Journals (Sweden)

    Thomas C. Hart

    2013-09-01

    Full Text Available Early Archaic subsistence strategies of New England remain poorly understood despite their importance in helping researchers understand how people adapt to changing landscapes following the end of the last glacial maximum (21,000-14,000 B.P.. Excavations at the Mashantucket Pequot Reservation in Mashantucket, Connecticut during the 1990s revealed a large, semi-sedentary village nestled alongside a complex wetland ecosystem. In this paper, we present preliminary starch grain analysis of several stone tools recovered and curated from these excavations. The results of this study indicate that both transitory and reserve starch grains are preserved on these artifacts and that at least one of the artifacts may have been used for leaf or stem processing. The results of this study also demonstrate the potential for future research in which paired macrobotanical and residue analysis will allow for a better understanding of subsistence practices at the site and during the early Archaic in general.

  4. Preliminary evidence for an association of a dinucleotide repeat polymorphism at the MAOA gene with early onset alcoholism/substance abuse

    Energy Technology Data Exchange (ETDEWEB)

    Vanyukov, M.M.; Moss, H.B.; Tarter, R.E. [Univ. of Pittsburg, PA (United States)] [and others

    1995-04-24

    An association between the liability to early onset alcoholism/substance abuse and a recently discovered dinucleotide repeat length polymorphism at the MAOA gene (MAOCA-1) was examined using polymerase chain reaction (PCR). A significant correlation between the presence/absence of the disorder and the length of the MAOCA-1 repeat was found in males, but not females, with {open_quotes}long{close_quotes} alleles (repeat length above 115 bp) associated with both increased risk for the disorder and lower age of onset of substance abuse. These preliminary data suggest that further exploration of the relationship between the MAOA gene and behavioral traits in an expanded sample is warranted. 22 refs., 1 fig., 3 tabs.

  5. Technologies for Expanding the Reach of Evidence-Based Interventions: Preliminary Results for Promoting Social-Emotional Development in Early Childhood

    Science.gov (United States)

    Baggett, Kathleen M.; Davis, Betsy; Feil, Edward G.; Sheeber, Lisa L.; Landry, Susan H.; Carta, Judith J.; Leve, Craig

    2010-01-01

    In great demand are efficient mechanisms for delivery of evidence-based interventions for promoting social-emotional development and early positive behavior of all children, and especially for those with or at risk for disabilities. The rise of Internet use has created potentially new avenues for intervention delivery, which, when paired with the…

  6. Preliminary evidence for association of genetic variants in pri-miR-34b/c and abnormal miR-34c expression with attention deficit and hyperactivity disorder.

    Science.gov (United States)

    Garcia-Martínez, I; Sánchez-Mora, C; Pagerols, M; Richarte, V; Corrales, M; Fadeuilhe, C; Cormand, B; Casas, M; Ramos-Quiroga, J A; Ribasés, M

    2016-01-01

    Attention deficit and hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by impairment to sustain attention and inability to control impulses and activity level. The etiology of ADHD is complex, with an estimated heritability of 70-80%. Under the hypothesis that alterations in the processing or target binding of microRNAs (miRNAs) may result in functional alterations predisposing to ADHD, we explored whether common polymorphisms potentially affecting miRNA-mediated regulation are involved in this psychiatric disorder. We performed a comprehensive association study focused on 134 miRNAs in 754 ADHD subjects and 766 controls and found association between the miR-34b/c locus and ADHD. Subsequently, we provided preliminary evidence for overexpression of the miR-34c-3p mature form in peripheral blood mononuclear cells of ADHD subjects. Next, we tested the effect on gene expression of single-nucleotide polymorphisms within the ADHD-associated region and found that rs4938923 in the promoter of the pri-miR-34b/c tags cis expression quantitative trait loci for both miR-34b and miR-34c and has an impact on the expression levels of 681 transcripts in trans, including genes previously associated with ADHD. This gene set was enriched for miR-34b/c binding sites, functional categories related to the central nervous system, such as axon guidance or neuron differentiation, and serotonin biosynthesis and signaling canonical pathways. Our results provide preliminary evidence for the contribution to ADHD of a functional variant in the pri-miR-34b/c promoter, possibly through dysregulation of the expression of mature forms of miR-34b and miR-34c and some target genes. These data highlight the importance of abnormal miRNA function as a potential epigenetic mechanism contributing to ADHD. PMID:27576168

  7. Migration and maternity: insights of context, health policy, and research evidence on experiences and outcomes from a three country preliminary study across Germany, Canada, and the United kingdom.

    Science.gov (United States)

    Higginbottom, Gina; Reime, Birgit; Bharj, Kuldip; Chowbey, Punita; Ertan, Kubilay; Foster-Boucher, Caroline; Friedrich, Jule; Gerrish, Kate; Kentenich, Heribert; Mumtaz, Zubia; O'Brien, Beverley; Salway, Sarah

    2013-01-01

    A group from Germany, Canada, and the United Kingdom undertook country-specific scoping reviews and stakeholder consultations before joining to holistically compare migration and maternity in all three countries. We examined four interlinking dimensions to understand how international migrant/minority maternal health might be improved upon using transnational research: (a) wider sociopolitical context, (b) health policy arena, (c) constellation, outcomes, and experiences of maternity services, and (d) existing research contexts. There was clear evidence that the constellation and delivery of services may undermine good experiences and outcomes. Interventions to improve access and quality of care remain small scale, short term, and lacking in rigorous evaluation. PMID:23631670

  8. Paleopathological evidence of the cranial remains from the Sima de los Huesos Middle Pleistocene site (Sierra de Atapuerca, Spain). Description and preliminary inferences.

    Science.gov (United States)

    Pérez, P J; Gracía, A; Martínez, I; Arsuaga, J L

    1997-01-01

    The large Sima de los Huesos sample provides for the first time the opportunity of performing a paleopathological study of a Middle Pleistocene population. A high frequency of bilateral temporomandibular arthropathy has been observed. We found an ear hyperostosis in Cranium 4, that probably caused deafness that we consider to be of infectious origin. Three osteomata were found in the cranial collection. One severe trauma was evident on the left supraorbital torus of an immature individual. Many cranial vault erosions, mostly restricted to the external table, are found in the sample. Cranium 5 displays thirteen of these. Cranium 5 also shows an extensive maxillary osteitis associated with a dental apical abscess, as well as another dental apical abscess in its mandible. Most of the adult frontal bones show a worm-like pattern of vascular channelling in the orbital roof, also found in modern populations. PMID:9300348

  9. Characterizing slab inputs in the earliest stages of subduction: Preliminary evidence from fluid-mobile element systematics for IODP Expedition 352 recovered volcanic samples

    Science.gov (United States)

    Sanatan, Keir; Ryan, Jeffrey; Atlas, Zachary; Reagan, Mark

    2016-04-01

    IODP Expedition 352 recovered ~1.22 km of boninitic and basaltic volcanic rocks from four sites in the Izu-Bonin forearc to examine the volcanic phenomena associated with subduction initiation. While the recovered forearc basalts give little indication for the involvement of slab-derived volatiles, the extensive sequences of boninite series lavas recovered up-section show physical evidence for extensive fluid involvement (heavy vesicularity, explosive eruptive style), along with chemistries indicative of fluid-addition melting of depleted mantle sources. We are attempting to assay the makeup and likely slab provenance of these fluids via their fluid-mobile element (B, As, Cs, Sb, Pb, Li) systematics. Boron abundances measured thus far in fresh boninitic glasses recovered from Holes U1439C and U1442A range from 3-12 ppm, with B/Be and B/La ranging from 7.5-106 and 2-18.5, respectively. While the highest values are comparable to those observed in the most B-enriched Izu-bonin arc rocks, most of the data are at the low end of this range. Cs/Th and Pb/Ce ratios encompass the range of values encountered in IBM boninites in the literature, and are comparable to values for Izu arc lavas, while As/Sm ratios appear to be lower than in arc suites. Li concentrations are elevated relative to basaltic lavas, at 7-17 ppm, and Li/Yb ratios range from 8-22, a factor of four higher than the range encountered in volcanic arc suites. While fluid-mobile element systematics of Izu-Bonin volcanic arc lavas show evidence for inputs of two unique slab components with markedly different fluid-mobile element enrichments, the Izu-Bonin boninites can best be explained as simple mixtures of very depleted mantle and a single slab phase with high abundances of fluid-mobile species, along with elevated K, Ba, and other common subduction indicator species. Volcanic arc lavas globally show evidence for a fluid-mobile element enriched component that appears to be similar to serpentinite

  10. THE EMBEDDEDNESS OF ENTREPRENEURSHIP EDUCATION IN THE CURRICULA OF NON-BUSINESS UNIVERSITY PROGRAMMES: PRELIMINARY EVIDENCE FROM SOUTH AFRICAN UNIVERSITIES OF TECHNOLOGY

    Directory of Open Access Journals (Sweden)

    Robertson K. Tengeh

    2015-06-01

    Full Text Available The total early stage entrepreneurial activity (TEA in South Africa is said to be extremely low compared to those of other sub-Saharan countries. This is despite the concerted efforts of the government to establish, develop and nurture entrepreneurship at all levels, especially among the youths. This calls for concern given the current state of the economy and the challenges faced by South Africa’s future generation. This paper is anchored on two theoretical frameworks to substantiate our argument for the inclusion of entrepreneurship education in the curricula of non-business programmes at universities of technology. The theoretical frameworks are the contingency organizational theory and the magnet versus radiant model. The study adopted an exploratory cross sectional research design which allowed us to collect data from a cross-section of a population: the universities of technology in South Africa. The findings suggest that only fifteen (out of the 46 of the programmes showed visible evidence of entrepreneurship/business studies in their content. Such finding implies that there is a need for entrepreneurship to be integrated into the curricula of all non-business departments if not for the sake of its perceived employment generation attributes, but for its other attributes such as innovation, and more importantly employability.

  11. Preliminary evidences of CCM operation and its down regulation in relation to increasing CO2 levels in natural phytoplankton assemblages from the coastal waters of Bay of Bengal

    Science.gov (United States)

    Biswas, Haimanti; Rahman Shaik, Aziz Ur; Bandyopadhyay, Debasmita

    2014-05-01

    Bay of Bengal (BoB), a low productive part of the North Indian Ocean, often possesses low CO2 levels in its surface water and diatoms dominate the phytoplankton communities. Virtually no studies are available from this area reporting how this diatom dominated phytoplankton community would respond any increase in dissolved CO2 levels either naturally or anthopogenically. In most of the marine phytoplankton, the inefficiency of the sole carbon fixing enzyme Rubisco necessitates the need of concentrating dissolved inorganic carbon (DIC) (mostly as HCO3) inside the cell in excess of the ambient water concentrations in order to maintain high rate of photosynthesis under low CO2 levels through an energy consuming carbon concentration mechanisms (CCMs). The ubiquitous enzyme carbonic anhydrase (CA) plays a vital role in CCMs by converting HCO3- to CO2 and usually utilizes the trace metal zinc (Zn) as a cofactor. However, it is evident in many marine phytoplankton species that with increasing external CO2 levels, CCMs can be down-regulated leading to energetic savings which can be reallocated to growth; although exceptions occur. Hence, in order to predict their responses to the projected changes, it is imperative to understand their carbon metabolism patterns. We have conducted a series of incubation experiments in microcosms with natural phytoplankton communities from the coastal waters of BoB under different CO2 levels. Our results revealed that the rate of net photosynthetic oxygen evolution and biomass build-up increased in response to increasing CO2 levels. The depletion in δ13CPOM values were more in the high CO2 treatments relative to the low CO2 treated cells (control), indicating that dissolved CO2 uptake was higher when CO2 levels were increased. When additional Zn was added to the low CO2 treated cells, net photosynthetic oxygen evolution rate was increased significantly than that of the untreated control. It is likely that upon the supply of Zn under low CO2

  12. Rare K0 decays (preliminary)

    International Nuclear Information System (INIS)

    The preliminary results are obtained in the NA48 experiment at CERN SPS: the first evidence for the decay of Ks → π+π-e+e-, an upper limit estimation for Br (Ks → π0e+e-), and the measurement of the branching ratios of Ks decays into two γ's, and KL decays into e+e-e+e-, π0γγ and e+e-γγ. (author)

  13. Preliminary Monthly Climatological Summaries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Preliminary Local Climatological Data, recorded since 1970 on Weather Burean Form 1030 and then National Weather Service Form F-6. The preliminary climate data...

  14. Purification and immunochemical properties of Escherichia coli B polysaccharide cross-reacting with Salmonella typhi Vi antigen: preliminary evidence for cross-reaction of the polysaccharide with Escherichia coli K1 antigen.

    OpenAIRE

    B. Szewczyk; A Taylor

    1983-01-01

    An acidic polysaccharide of Escherichia coli B was isolated by a mild procedure and purified to homogeneity. The polysaccharide was found to react in Salmonella typhi Vi antisera and E. coli K1 antisera. Serological analysis and preliminary chemical characterization of the polysaccharide indicated that it is an aminouronic acid polymer which, although not structurally identical to either Vi or K1, appears more like the Vi antigen, both immunochemically and chemically.

  15. A Preliminary Study on Legal Validity of Electronic Signatures and Electronic Signatures Evidence%关于电子签名法律效力及作为证据的初步探析

    Institute of Scientific and Technical Information of China (English)

    陶阳

    2015-01-01

    Electronic signature has been widel and frequently used nowadays. However, as for the va-lidity of electronic contracts and electronic signatures in legal proceedings, together with the issue of how to use electronic signature evidence, the relative regulations are not clear. Based on the basic theo-ry of electronic signatures and the law of evidence, analyzes the effectiveness of China' s electronic sig-nature and the requirements of the form of electronic evidence. Finally, in judicial practice, through e-lectronic signature and other documents we can form a complete chain of evidence, improve the chances of adoption of the judiciary, and eventually safeguard people' s legitimate rights and interests.%21世纪,随着电子化的繁荣发展,电子签名的适用也越来越频繁,而在诉讼中如何确认电子合同及电子签名的效力,以及作为证据使用时需要注意的事项,还比较模糊. 本文力图从电子签名和证据法的基本理论入手,分析中国电子签名的效力及电子证据形式的要求. 最后在司法实践中,通过电子签名与其他文件相印证的方式使得形成一个完整的证据链,来提高司法机关采纳的几率,以便在产生纠纷时,维护好自己的合法权益.

  16. A Preliminary Evaluation of DNA Evidence in Criminal Investigations Based on National DNA Database%基于数据库数据分析的DNA证据作用评价

    Institute of Scientific and Technical Information of China (English)

    刘冰

    2015-01-01

    ABATRACT:For the last decade, China national DNA database has expanded exponentially, and held tens of millions of data, including not only the DNA proifles, but also a large amount of relevant information, related to crime scenes, evidence, individuals, etc. This paper attempts to evaluate the function of DNA evidence and DNA analysis in criminal investigations. Data in the national DNA database uploaded from 2011 to 2014 was selected, and a systematic analysis is carried out on multiple dimensions, such as time, evidence type, crime type, match rate, etc. As expected, DNA analysis has an outstanding performance in criminal investigations either in case solving or crime linking with the effective utilization rate close to 50%. It emerges as a powerful tool in criminal investigations, especially in rape cases with matching rate of evidence (MRe) of 71.1%, and murder case at 62.1% of matching rate. The DNA evidence also plays signiifcant role in ifghting against professional crimes from 2011 to 2014, in which the evidence for theft and drug cases rises to 124%, 477.3%, and the match number up to 55.3%, 378.6%, respectively. By the systematic analysis of the practical value of common biological evidence, it reveals that traditional biological sample, like blood, semen and saliva (including cigarette butt), covers 82.8% of all the samples detected in DNA laboratories, while new types of samples are becoming more popular. During the same period of time, the number of touch DNA evidence has a growth of 241.7% in total and the match number rises to 158.5%. This paper also proposes that the key evidence should be carefully collected according to the speciifc type of crime scene to make sure that the evidence won’t be compromised in the following investigation and litigation.%始建于2003年的全国公安机关DNA数据库10余年来累积了千万级的数据信息,其中除DNA分型等技术数据外,还包括大量的案件、物证、人员的相关信息。

  17. A preliminary study in ward administration guided by evidence-based nursing%循证护理学指导的病房管理工作初探

    Institute of Scientific and Technical Information of China (English)

    周叶英; 徐冬梅; 温士玲

    2010-01-01

    To explore the method and result of ward administration guided by evidence-based nursing. On the net of China National Knowledge Infrastructure, the useful data about nursing errors were retrieved, then arrange in order of treating them and put emphasis on the clinical pharmacological managing. One year later, the nursing error amounts were compared. Of the reference documentations between January 2006 to December 2007,2 181 clinical nursing errors covered 10 years periods, of them referring drug using occupied 81.2%. The others were managed order 11.0% , nursing record 5. 2% and nursing handle 2. 5%. Administrating the ward according to the new management model the nursing errors reduced from around 18 to 5 comparing the former years. Due to evidence-based nursing guidance, the ward administration becomes systematic and orderly and the nursing errors going down apparently.%探讨循证护理学指导的病房管理工作方法和效果.在中国医院知识库网站搜集有关护理差错的文献,分类整理后找出病房管理的重点,实施改进措施后与往年的差错数量比较.在2006~2007年的文献中搜集到10年间发生的2 181件临床护理差错,与药物使用有关的差错占81.2%,其他依次为医嘱处理11.0%、护理记录5.2%、护理处置2.5%.按新模式进行病房管理后,1年内的差错由17~18件减少到5件.在循证护理学指导下,病房管理工作重点突出,有条不紊,护理差错明显下降.

  18. UVISS preliminary visibility analysis

    DEFF Research Database (Denmark)

    Betto, Maurizio

    1998-01-01

    The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part of the...

  19. BIOMOD - preliminary findings

    International Nuclear Information System (INIS)

    Certain preliminary findings on the workings of the biosphere code BIOMOD are presented. These are intended as the basis for technical discussions relating to the development of BIOMOD1. Discussion is restricted to observations on the relationships between user-defined input and i) relative significance of different pathways for activity transfer to man, ii) total activity consumption by man, and iii) activity released to dose conversion factors to be used in SYVAC. (author)

  20. On Preliminary Breakdown

    Science.gov (United States)

    Beasley, W. H.; Petersen, D.

    2013-12-01

    The preliminary breakdown phase of a negative cloud-to-ground lightning flash was observed in detail. Observations were made with a Photron SA1.1 high-speed video camera operating at 9,000 frames per second, fast optical sensors, a flat-plate electric field antenna covering the SLF to MF band, and VHF and UHF radio receivers with bandwidths of 20 MHz. Bright stepwise extensions of a negative leader were observed at an altitude of 8 km during the first few milliseconds of the flash, and were coincident with bipolar electric field pulses called 'characteristic pulses'. The 2-D step lengths of the preliminary processes were in excess of 100 meters, with some 2-D step lengths in excess of 200 meters. Smaller and shorter unipolar electric field pulses were superposed onto the bipolar electric field pulses, and were coincident with VHF and UHF radio pulses. After a few milliseconds, the emerging negative stepped leader system showed a marked decrease in luminosity, step length, and propagation velocity. Details of these events will be discussed, including the possibility that the preliminary breakdown phase consists not of a single developing lightning leader system, but of multiple smaller lightning leader systems that eventually join together into a single system.

  1. Examining the Reinforcing Properties of Making Sense: A Preliminary Investigation

    Science.gov (United States)

    Wray, Alisha M.; Dougher, Michael J.; Hamilton, Derek A.; Guinther, Paul M.

    2012-01-01

    Acceptance and commitment therapy asserts that in clinical problems such as rumination and depression, making sense continues despite accompanying aversive consequences, because sense-making is reinforcing, particularly when it leads to experiential avoidance. The following series of experiments aimed to provide preliminary empirical evidence for…

  2. Emergent Writing in Preschoolers: Preliminary Evidence for a Theoretical Framework

    Science.gov (United States)

    Puranik, Cynthia S.; Lonigan, Christopher J.

    2014-01-01

    Researchers and educators use the term "emergent literacy" to refer to a broad set of skills and attitudes that serve as foundational skills for acquiring success in later reading and writing; however, models of emergent literacy have generally focused on reading and reading-related behaviors. Hence, the primary aim of this study was to…

  3. Preliminary Evidence for Impaired Rapid Verb Generation in Schizophrenia

    Science.gov (United States)

    Woods, Steven Paul; Weinborn, Michael; Posada, Carolina; O'Grady, Joy

    2007-01-01

    It has been hypothesized that nouns and verbs are processed within relatively separable semantic memory networks. Although abnormal semantic processing is a common feature of schizophrenia-spectrum disorders, no prior studies have specifically examined the comparability of noun and verb generation deficits in schizophrenia. In the current study,…

  4. Preliminary evidence for a phage in sewage utilizing Clostridium thermoaceticum

    Energy Technology Data Exchange (ETDEWEB)

    Misra, A.K.; Bose, N.K.; Uyamadu, N.; Agrawal, P.K. (Atlanta University Center, Atlanta, GA (USA))

    1990-03-01

    Briefly describes a method for isolating bacteriophages (viruses which infect bacteria) from {ital Clostridium thermoaceticum}. Water samples were anaerobically collected from the local sewage plant and sterile filtered inside a Coy-anaerobic chamber. Filtrate from the sewage liquid was added to the cultures of {ital C thermoaceticum} for observing lysis. Sterile filtrate was autoclaved (and/or treated with detergent) and added to bacterial cultures. Filtrates from lysed cultures were serially transferred from one culture to another. Virus (phage) was purified by ultracentrifugation in the form of pellets and stored at 4{degree}C in VSM (virus suspending medium). Phages were also observed under electron microscope after negative staining with glutaraldehyde. The sterile filtrate from sewage plant lysed the bacterial cultures, while the autoclaved and detergent treated was ineffective. Cultures where sterile water was added as controls grew normally. Reduced growth due to the addition of autoclaved filtrate could have resulted from the presence of bactericins. Virus by purified ultracentrifugation was also very effective in lysing the cultures. Though not very clear, icosahedral particles of the viruses were seen under the electron microscope. Further studies with this phage are in progress with the aim of obtaining a lysogenic strain (or developing one by mutagenesis) for its use as vector to transfer the genes for co-dehydrogenase and formate-dehydrogenase, the key enzymes involved in the conversion of CO or syngas into acetic acid by this organism. 14 refs., 1 fig.

  5. Environmental Survey preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    1988-04-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Sandia National Laboratories conducted August 17 through September 4, 1987. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with Sandia National Laboratories-Albuquerque (SNLA). The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at SNLA, and interviews with site personnel. 85 refs., 49 figs., 48 tabs.

  6. OMEGA Upgrade preliminary design

    International Nuclear Information System (INIS)

    The OMEGA laser system at the Laboratory for Laser Energetics of the University of Rochester is the only major facility in the United States capable of conducting fully diagnosed, direct-drive, spherical implosion experiments. As such, it serves as the national Laser Users Facility, benefiting scientists throughout the country. The University's participation in the National Inertial Confinement Fusion (ICF) program underwent review by a group of experts under the auspices of the National Academy of Sciences (the Happer Committee) in 1985. The Happer Committee recommended that the OMEGA laser be upgraded in energy to 30 kJ. To this end, Congress appropriated $4,000,000 for the preliminary design of the OMEGA Upgrade, spread across FY88 and FY89. This document describes the preliminary design of the OMEGA Upgrade. The proposed enhancements to the existing OMEGA facility will result in a 30-kHJ, 351-nm, 60-beam direct-drive system, with a versatile pulse-shaping facility and a 1%--2% uniformity of target drive. The Upgrade will allow scientists to explore the ignition-scaling regime, and to study target behavior that is hydrodynamically equivalent to that of targets appropriate for a laboratory microfusion facility (LMF). In addition, it will be possible to perform critical interaction experiments with large-scale-length uniformly irradiated plasmas

  7. Preliminary Equipment List

    International Nuclear Information System (INIS)

    The methodology for assigning equipment identifiers and component identifiers for the MGR Site Recommendation or License Application is presented below. Engineering Computer Support (ECS) assigns all equipment and component identifiers and is responsible for entering equipment identifiers into the Plant Design System (PDS) Master Equipment List. A sample report from the PDS Master Equipment List is attached. The attached report is representative of the information that will be provided by the PDS system. Since the equipment list presented is only preliminary, actual equipment numbers are not assigned. It contains information required to maintain control of the equipment and components for MGR important to safety systems. Definitions for the fields that currently exist on the PDS Master Equipment List are given

  8. A Preliminary Jupiter Model

    CERN Document Server

    Hubbard, W B

    2016-01-01

    In anticipation of new observational results for Jupiter's axial moment of inertia and gravitational zonal harmonic coefficients from the forthcoming Juno orbiter, we present a number of preliminary Jupiter interior models. We combine results from ab initio computer simulations of hydrogen-helium mixtures, including immiscibility calculations, with a new nonperturbative calculation of Jupiter's zonal harmonic coefficients, to derive a self-consistent model for the planet's external gravity and moment of inertia. We assume helium rain modified the interior temperature and composition profiles. Our calculation predicts zonal harmonic values to which measurements can be compared. Although some models fit the observed (pre-Juno) second- and fourth-order zonal harmonics to within their error bars, our preferred reference model predicts a fourth-order zonal harmonic whose absolute value lies above the pre-Juno error bars. This model has a dense core of about 12 Earth masses, and a hydrogen-helium-rich envelope with...

  9. Preliminary design county plan Zeeland

    International Nuclear Information System (INIS)

    The preliminary design 'Streekplan Zeeland' (Country plan Zeeland, with regard to the location of additional nuclear power plants in Zeeland, the Netherlands) has passed through a consultation and participation round. Thereupon 132 reactions have been received. These have been incorporated and answered in two notes. This proposal deals with the principal points of the preliminary design and treats also the remarks of the committees Environmental (town and country) Planning (RO), Provincial (town and country) Planning Committee (PPC) and Association of Communities of Zeeland (VZG), on the reply notes. The preliminary design with the modifications, collected in appendix 3, is proposed to be the starting point in the drawing-up of the design-country-plan. This design subsequently will pass the formal country-plan procedure. (author). 1 fig

  10. Technetium removal: preliminary flowsheet options

    International Nuclear Information System (INIS)

    This document presents the results of a preliminary investigation into options for preliminary flowsheets for 99Tc removal from Hanford Site tank waste. A model is created to show the path of 99Tc through pretreatment to disposal. The Tank Waste Remediation (TWRS) flowsheet (Orme 1995) is used as a baseline. Ranges of important inputs to the model are developed, such as 99Tc inventory in the tanks and important splits through the TWRS flowsheet. Several technetium removal options are discussed along with sensitivities of the removal schemes to important model parameters

  11. Space reactor preliminary mechanical design

    International Nuclear Information System (INIS)

    An analysis was performed on the SABRE reactor space power system to determine the effect of the number and size of heat pipes on the design parameters of the nuclear subsystem. Small numbers of thin walled heat pipes were found to give a lower subsystem mass, but excessive fuel swelling resulted. The SP-100 preliminary design uses 120 heat pipes because of acceptable fuel swelling and a minimum nuclear subsystem mass of 1875 kg. Salient features of the reactor preliminary design are: individual fuel modules, ZrO2 block core mounts, bolted collar fuel module restraints, and a BeO central plug

  12. Preliminary test-shrinkage estimators

    Directory of Open Access Journals (Sweden)

    H. H. Lemmer

    1983-03-01

    Full Text Available The advantages of using the very simple shrinkage estimator TL proposed by Lemmer rather than that proposed by Mehta and Srivivasan in the case of preliminary test estimators for parameters of the normal, binomial and Poisson distributions are examined.

  13. 40 CFR 158.345 - Preliminary analysis.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Preliminary analysis. 158.345 Section... REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.345 Preliminary analysis. (a) If the product is produced by an integrated system, the applicant must provide a preliminary analysis of each technical grade...

  14. 40 CFR 161.170 - Preliminary analysis.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Preliminary analysis. 161.170 Section... Preliminary analysis. (a) If the product is produced by an integrated system, the applicant must provide a preliminary analysis of each technical grade of active ingredient contained in the product to identify...

  15. 19 CFR 351.205 - Preliminary determination.

    Science.gov (United States)

    2010-04-01

    ... determinations, postponement of preliminary determinations, notices of preliminary determinations, and the... its injury determination. (e) Postponement at the request of the petitioner. A petitioner must submit a request for postponement of the preliminary determination (see section 703(c)(1)(A) or section...

  16. Radioactive waste shredding: Preliminary evaluation

    International Nuclear Information System (INIS)

    The critical constraints for sizing solid radioactive and mixed wastes for subsequent thermal treatment were identified via a literature review and a survey of shredding equipment vendors. The types and amounts of DOE radioactive wastes that will require treatment to reduce the waste volume, destroy hazardous organics, or immobilize radionuclides and/or hazardous metals were considered. The preliminary steps of waste receipt, inspection, and separation were included because many potential waste treatment technologies have limits on feedstream chemical content, physical composition, and particle size. Most treatment processes and shredding operations require at least some degree of feed material characterization. Preliminary cost estimates show that pretreatment costs per unit of waste can be high and can vary significantly, depending on the processing rate and desired output particle size

  17. Preliminary Results Towards Contract Monitorability

    OpenAIRE

    Vella, Annalizz; Francalanza, Adrian

    2016-01-01

    This paper discusses preliminary investigations on the monitorability of contracts for web service descriptions. There are settings where servers do not guarantee statically whether they satisfy some specified contract, which forces the client (i.e., the entity interacting with the server) to perform dynamic checks. This scenario may be viewed as an instance of Runtime Verification, where a pertinent question is whether contracts can be monitored for adequately at runtime, otherwise stated as...

  18. Preliminary Concepts of Dynamical Systems

    Directory of Open Access Journals (Sweden)

    Nayana Mukherjee

    2012-08-01

    Full Text Available Dynamical system is a young and vigorously growing area of research which promises enormous potential and opportunities. This paper aims to  introduce some of the  preliminary concepts of dynamical systems.   Many application sides of the subject are noted to encourage the reader for future developments. Resources are supplied in the references for   further reading.

  19. Preliminary Estimates of Diaspora Savings

    OpenAIRE

    Ratha, Dilip; Mohapatra, Sanket

    2011-01-01

    Preliminary estimates, based on data on bilateral migrant stocks for 2010 and assumptions about migrant incomes, suggest that annual diaspora savings of developing countries could be in the range of $400 billion. Diaspora saving as a share of Gross Domestic Product (GDP) is estimated to be 2.3 percent in middle-income countries and as high as 9 percent in low-income countries.

  20. Exploratory shaft facility preliminary designs - Permian Basin

    International Nuclear Information System (INIS)

    The purpose of the Preliminary Design Report, Permian Basin, is to provide a description of the preliminary design for an Exploratory Shaft Facility in the Permian Basin, Texas. This issue of the report describes the preliminary design for constructing the exploratory shaft using the Large Hole Drilling method of construction and outlines the preliminary design and estimates of probable construction cost. The Preliminary Design Report is prepared to complement and summarize other documents that comprise the design at the preliminary stage of completion, December 1982. Other design documents include drawings, cost estimates and schedules. The preliminary design drawing package, which includes the construction schedule drawing, depicts the descriptions in this report. For reference, a list of the drawing titles and corresponding numbers are included in the Appendix. The report is divided into three principal sections: Design Basis, Facility Description, and Construction Cost Estimate. 30 references, 13 tables

  1. Development and Preliminary Validation of the Time Management for Exercise Scale

    Science.gov (United States)

    Hellsten, Laurie-ann M.; Rogers, W. Todd

    2009-01-01

    The purpose of this study was to collect preliminary validity evidence for a time management scale for exercise. An initial pool of 91 items was developed from existing literature. Ten exercise/health psychologists evaluated each of the items in terms of relevance and representativeness. Forty-nine items met all criteria. Exploratory factor…

  2. Preliminary weight and cost estimates for transport aircraft composite structural design concepts

    Science.gov (United States)

    1973-01-01

    Preliminary weight and cost estimates have been prepared for design concepts utilized for a transonic long range transport airframe with extensive applications of advanced composite materials. The design concepts, manufacturing approach, and anticipated details of manufacturing cost reflected in the composite airframe are substantially different from those found in conventional metal structure and offer further evidence of the advantages of advanced composite materials.

  3. Preliminaries

    OpenAIRE

    de Freud, Desde el Jardín

    2014-01-01

    Desde el Jardín de Freud se encuentra indexada en el IBN-Publindex (Colciencias), en categoría C, y en Latindex. También se encuentra en las siguientes bases de datos y catálogos: ebsco, Dialnet, Rebiun, Doaj y e-Revistas.

  4. Preliminaries

    Directory of Open Access Journals (Sweden)

    Desde el jardín de Freud

    2014-10-01

    Full Text Available Desde el Jardín de Freud se encuentra indexada en el IBN-Publindex (Colciencias, en categoría C, y en Latindex. También se encuentra en las siguientes bases de datos y catálogos: ebsco, Dialnet, Rebiun, Doaj y e-Revistas.

  5. Preliminary ECLSS waste water model

    Science.gov (United States)

    Carter, Donald L.; Holder, Donald W., Jr.; Alexander, Kevin; Shaw, R. G.; Hayase, John K.

    1991-01-01

    A preliminary waste water model for input to the Space Station Freedom (SSF) Environmental Control and Life Support System (ECLSS) Water Processor (WP) has been generated for design purposes. Data have been compiled from various ECLSS tests and flight sample analyses. A discussion of the characterization of the waste streams comprising the model is presented, along with a discussion of the waste water model and the rationale for the inclusion of contaminants in their respective concentrations. The major objective is to establish a methodology for the development of a waste water model and to present the current state of that model.

  6. ITER cryopump handling study preliminary report

    International Nuclear Information System (INIS)

    The scope of this study was to develop a remote handling concept for the primary vacuum pumping system by performing the following tasks: review the cryopump duct configuration and remote handling requirements for cryopump replacement; initiate an ITER Cryopump Maintenance Requirements Definition Document; develop a preliminary, compatible design concept ; propose preliminary maintenance procedures for cryopump replacement; develop a preliminary development schedule, breakdown structure and ROM costs. 3 tabs., 4 figs

  7. 33 CFR 116.10 - Preliminary review.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Preliminary review. 116.10... ALTERATION OF UNREASONABLY OBSTRUCTIVE BRIDGES § 116.10 Preliminary review. (a) Upon receipt of a written complaint, the District Commander will review the complaint to determine if, in the District...

  8. Plutonium Immobilization Can Loading Preliminary Specifications

    Energy Technology Data Exchange (ETDEWEB)

    Kriikku, E.

    1998-11-25

    This report discusses the Plutonium Immobilization can loading preliminary equipment specifications and includes a process block diagram, process description, equipment list, preliminary equipment specifications, plan and elevation sketches, and some commercial catalogs. This report identifies loading pucks into cans and backfilling cans with helium as the top priority can loading development areas.

  9. 7 CFR 1735.90 - Preliminary approvals.

    Science.gov (United States)

    2010-01-01

    ... preliminary approval to the acquisition or merger. However, the borrower may not obtain additional loan funds...) Before RUS will grant preliminary approval, the borrower shall submit: (1) Merger or acquisition documents required by state law; (2) Acquisition agreements covering the transaction; (3) Any...

  10. KALIMER preliminary conceptual design report

    International Nuclear Information System (INIS)

    This report, which summarizes the result of preliminary conceptual design activities during Phase 1, follows the format of safety analysis report. The purpose of publishing this report is to gather all of the design information developed so far in a systematic way so that KALIMER designers have a common source of the consistent design information necessary for their future design activities. This report will be revised and updated as design changes occur and more detailed design specification is developed during Phase 2. Chapter 1 describes the KALIMER Project. Chapter 2 includes the top level design requirements of KALIMER and general plant description. Chapter 3 summarizes the design of structures, components, equipment and systems. Specific systems and safety analysis results are described in the remaining chapters. Appendix on the HCDA evaluation is attached at the end of this report

  11. KALIMER preliminary conceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, Do Hee; Kim, Y. J.; Kim, Y. G. and others

    2000-08-01

    This report, which summarizes the result of preliminary conceptual design activities during Phase 1, follows the format of safety analysis report. The purpose of publishing this report is to gather all of the design information developed so far in a systematic way so that KALIMER designers have a common source of the consistent design information necessary for their future design activities. This report will be revised and updated as design changes occur and more detailed design specification is developed during Phase 2. Chapter 1 describes the KALIMER Project. Chapter 2 includes the top level design requirements of KALIMER and general plant description. Chapter 3 summarizes the design of structures, components, equipment and systems. Specific systems and safety analysis results are described in the remaining chapters. Appendix on the HCDA evaluation is attached at the end of this report.

  12. Preliminary hazards analysis -- vitrification process

    Energy Technology Data Exchange (ETDEWEB)

    Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.

  13. Preliminary hazards analysis -- vitrification process

    International Nuclear Information System (INIS)

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility's construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment

  14. Quantitative evaluation of bronchial enhancement: preliminary observations

    Science.gov (United States)

    Odry, Benjamin L.; Kiraly, Atilla P.; Novak, Carol L.; Naidich, David P.; Godoy, Myrna C. B.; Schmidt, Bernhard

    2010-03-01

    It has been known for several years that airflow limitations in the small airways may be an important contributor to Chronic Obstructive Pulmonary Disease (COPD). Quantification of wall thickness has lately gained attention thanks to the use of high resolution CT, with novel approaches focusing on automated methods that can substitute for visual assessment [1, 2]. While increased thickening of the wall is considered evidence of inflammatory disease, we hypothesize that there may be additional ways to detect and quantify inflammation, specifically the uptake of contrast material. In this preliminary investigation, we selected patients with documented chronic airway inflammation, and for whom pre and post contrast datasets were available. On targeted reconstruction of right upper and lower lobes, we selected airways with no connections to surrounding structures, and used a modified Full-Width-Half-Max method for quantification of lumen diameter, wall thickness, and wall density. Matching airway locations on the pre- and postcontrast cases were compared. Airways from patients without airway disease served as a control. Results for the airway disease cases showed an average enhancement of 72 HU within the airway walls, with a standard deviation of 59 HU. In the control group the average enhancement was 16 HU with standard deviation of 22 HU. While this study is limited in number of cases, we hypothesize that quantification of contrast uptake is an additional factor to consider in assessing airway inflammation. At the same time we are currently investigating whether enhancement can be measured via a "contrast" map created with dual energy scanning, where a 3-value decomposition algorithm differentiates iodine from other materials. This technique would eliminate both the need for a pre-contrast scan, and the task of matching airway locations on pre- and post- scans.

  15. Preliminary Iron Distribution on Vesta

    Science.gov (United States)

    Mittlefehldt, David W.; Mittlefehldt, David W.

    2013-01-01

    The distribution of iron on the surface of the asteroid Vesta was investigated using Dawn's Gamma Ray and Neutron Detector (GRaND) [1,2]. Iron varies predictably with rock type for the howardite, eucrite, and diogenite (HED) meteorites, thought to be representative of Vesta. The abundance of Fe in howardites ranges from about 12 to 15 wt.%. Basaltic eucrites have the highest abundance, whereas, lower crustal and upper mantle materials (cumulate eucrites and diogenites) have the lowest, and howardites are intermediate [3]. We have completed a mapping study of 7.6 MeV gamma rays produced by neutron capture by Fe as measured by the bismuth germanate (BGO) detector of GRaND [1]. The procedures to determine Fe counting rates are presented in detail here, along with a preliminary distribution map, constituting the necessary initial step to quantification of Fe abundances. We find that the global distribution of Fe counting rates is generally consistent with independent mineralogical and compositional inferences obtained by other instruments on Dawn such as measurements of pyroxene absorption bands by the Visual and Infrared Spectrometer (VIR) [4] and Framing Camera (FC) [5] and neutron absorption measurements by GRaND [6].

  16. EUPORIAS: plans and preliminary results

    Science.gov (United States)

    Buontempo, C.

    2013-12-01

    Recent advances in our understanding and ability to forecast climate variability have meant that skilful predictions are beginning to be routinely made on seasonal to decadal (s2d) timescales. Such forecasts have the potential to be of great value to a wide range of decision-making, where outcomes are strongly influenced by variations in the climate. In 2012 the European Commission funded EUPORIAS, a four year long project to develop prototype end-to-end climate impact prediction services operating on a seasonal to decadal timescale, and assess their value in informing decision-making. EUPORIAS commenced on 1 November 2012, coordinated by the UK Met Office leading a consortium of 24 organisations representing world-class European climate research and climate service centres, expertise in impacts assessments and seasonal predictions, two United Nations agencies, specialists in new media, and commercial companies in climate-vulnerable sectors such as energy, water and tourism. The poster describes the setup of the project, its main outcome and some of the very preliminary results.

  17. Stardust Interstellar Preliminary Examination (ISPE)

    Science.gov (United States)

    Westphal, A. J.; Allen, C.; Bajt, S.; Basset, R.; Bastien, R.; Bechtel, H.; Bleuet, P.; Borg, J.; Brenker F.; Bridges, J.

    2009-01-01

    In January 2006 the Stardust sample return capsule returned to Earth bearing the first solid samples from a primitive solar system body, C omet 81P/Wild2, and a collector dedicated to the capture and return o f contemporary interstellar dust. Both collectors were approximately 0.1m(exp 2) in area and were composed of aerogel tiles (85% of the co llecting area) and aluminum foils. The Stardust Interstellar Dust Col lector (SIDC) was exposed to the interstellar dust stream for a total exposure factor of 20 m(exp 2-) day during two periods before the co metary encounter. The Stardust Interstellar Preliminary Examination ( ISPE) is a three-year effort to characterize the collection using no ndestructive techniques. The ISPE consists of six interdependent proj ects: (1) Candidate identification through automated digital microsco py and a massively distributed, calibrated search (2) Candidate extr action and photodocumentation (3) Characterization of candidates thro ugh synchrotronbased FourierTranform Infrared Spectroscopy (FTIR), S canning XRay Fluoresence Microscopy (SXRF), and Scanning Transmission Xray Microscopy (STXM) (4) Search for and analysis of craters in f oils through FESEM scanning, Auger Spectroscopy and synchrotronbased Photoemission Electron Microscopy (PEEM) (5) Modeling of interstell ar dust transport in the solar system (6) Laboratory simulations of h ypervelocity dust impacts into the collecting media

  18. Preliminary results of ANAIS-25

    CERN Document Server

    Amaré, J; Cuesta, C; García, E; Ginestra, C; Martínez, M; Oliván, M A; Ortigoza, Y; de Solórzano, A Ortiz; Pobes, C; Puimedón, J; Sarsa, M L; Villar, P; Villar, J A

    2013-01-01

    The ANAIS (Annual Modulation with NaI(Tl) Scintillators) experiment aims at the confirmation of the DAMA/LIBRA signal using the same target and technique at the Canfranc Underground Laboratory. 250 kg of ultrapure NaI(Tl) crystals will be used as a target, divided into 20 modules, each coupled to two photomultipliers. Two NaI(Tl) crystals of 12.5 kg each, grown by Alpha Spectra from a powder having a potassium level under the limit of our analytical techniques, form the ANAIS-25 set-up. The background contributions are being carefully studied and preliminary results are presented: their natural potassium content in the bulk has been quantified, as well as the uranium and thorium radioactive chains presence in the bulk through the discrimination of the corresponding alpha events by PSA, and due to the fast commissioning, the contribution from cosmogenic activated isotopes is clearly identified and their decay observed along the first months of data taking. Following the procedures established with ANAIS-0 and ...

  19. Preliminary design of smart fuel

    International Nuclear Information System (INIS)

    SMART (System-integrated Modular Advanced Reactor) is a novel light water rector with a modular, integral primary system configuration. This concept has been developing a 660 MWt by Korean Nuclear Power Industry Group with KAERI. SMART is being developed for use as an energy source for small-scale power generation and seawater desalination. Although the design of SMART is based on the current pressurized water reactor technology, new technologies such as enhanced safety, and passive safety have been applied, and system simplification and modularization, innovations in manufacturing and installation technologies have been implemented culminating in a design that has enhanced safety and economy, and is environment -friendly. In this paper described the preliminary design of the nuclear Fuel for this SMART, the design concept and the characteristics of SMART Fuel. In specially this paper describe the optimization of grid span adjustment to improve the thermal performance of the SMART Fuel as well as to improve the seismic resistance performance of the SMART Fuel, it is not easy to improve the both performance simultaneously because of design parameter of each performance inversely proportional. SMART Fuel enable to extra-long extended fuel cycle length and resistance of proliferation, enhanced safety, improved economics and reduced nuclear waste

  20. Preliminary project proposal : Missouri chutes, NE & IA

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This proposal is for the Missouri Chutes National Wildlife Refuge that would be in Nebraska and Iowa on the Missouri River. This preliminary project proposal...

  1. Alaska gold rush trails study: Preliminary draft

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Preliminary study draft, with maps, of seven gold rush trails in Alaska, to determine suitability for inclusion in the National Scenic Trails system and their...

  2. Preliminary design data package. Appendix C

    Energy Technology Data Exchange (ETDEWEB)

    1979-07-25

    The design requirements, design philosophy, method and assumptions, and preliminary computer-aided design of the Near-Term Hybrid Vehicle including its electric and heat power units, control equipment, transmission system, body, and overall vehicle characteristics are presented. (LCL)

  3. The Evidence Movement

    DEFF Research Database (Denmark)

    Hansen, Hanne Foss; Rieper, Olaf

    2009-01-01

    The evidence movement and the idea of systematic reviews, defined as summaries of the results of already existing evaluation and research projects, have gained considerable support in recent years as many international as well as national evidence-producing organizations have been established. This...... article analyses how the idea is practised in the areas of health, social welfare and education and shows that evidence-producing organizations work differently. Some subscribe to the hierarchy of evidence, others to a typology of evidence. The consequences of these variations are discussed....

  4. Preliminary organizational culture scale focused on artifacts

    OpenAIRE

    Bonavia, Tomas

    2006-01-01

    In this preliminary study, an organizational culture scale was developed to assess cultural artifacts according to Schein´s typology (1985). It includes a set of cultural artifacts to measure the extent to which an organization is more or less traditional. A total of 249 managers from a range of different companies responded to the items. Preliminary analysis yielded a one-dimensional scale with 14 items with high internal consistency and homogeneity.

  5. TPK preliminary activities in manufacturing nuclear equipment

    International Nuclear Information System (INIS)

    This paper gives a look into the preliminary activities of domestic industry in the conquest nuclear power program in the designing, engineering, quality assurance and manufacturing. TPK experiences in the preliminary activities in this field are shown in this article. review is given on te problem of basic materials. The general procedures are given in the future common action of domestic industry, and some efforts are made to discuss these problems, but they have not been discussed as much as possible. (author)

  6. Aircraft System Simulation for Preliminary Design

    OpenAIRE

    Krus, Petter; Braun, Robert; Nordin, Peter; Eriksson, Björn

    2012-01-01

    Developments in computational hardware and simulation software have come to a point where it is possible to use whole mission simulation in a framework for conceptual/preliminary design. This paper is about the implementation of full system simulation software for conceptual/preliminary aircraft design. It is based on the new Hopsan NG simulation package, developed at the Linköping University. The Hopsan NG software is implemented in C++. Hopsan NG is the first simulation software that has su...

  7. 12 CFR 611.1250 - Preliminary exit fee estimate.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Preliminary exit fee estimate. 611.1250 Section... System Institution Status § 611.1250 Preliminary exit fee estimate. (a) Preliminary exit fee estimate—terminating association. You must provide a preliminary exit fee estimate to us when you submit the plan...

  8. Project Rulison: A preliminary report

    International Nuclear Information System (INIS)

    Project Rulison was designed to use underground nuclear technology to determine the potential of this technique for commercial development of the deep, thick, lenticular, low permeability, Mesaverde Formation of the Rulison Field in Garfield County, Colorado. Since discovery in 1952, this reservoir has been tested by nine widely-spaced conventionally completed wells. A method of stimulation, far greater in magnitude and efficiency than conventional hydraulic fracturing, is needed to recover this gas at economic rates. A feasibility study completed in July 1966 indicated that nuclear explosives were a potentially economic method of stimulating recovery of natural gas from the reservoir. The gas-in-place, estimated to be between 90-125 billion cubic feet per 640 acres from earlier wells, was confirmed from information obtained on two conventional wells completed in 1966. The Project Rulison exploratory well, R-EX, was completed in May 1968. Detailed testing of this well provided data on geology, hydrology and reservoir characteristics. The data obtained from the testing have been used to determine the flow capacity of the Mesaverde reservoir. The reservoir characteristics were then used as input data to make predictions of post-shot reservoir performance in the nuclear stimulated well, using a radial, unsteady state gas flow computer model. A nuclear explosive with a design yield of 40 kilotons was emplaced in a 10-3/4 inch hole at a depth of 8426 feet below ground surface and detonated on September 10, 1969. A preliminary appraisal of the data taken at shot time indicate that the explosive behaved as predicted. The explosion was completely contained underground as predicted and no major seismic damage occurred. The post-shot drilling program, to reenter the chimney, will congruence in March 1970, approximately six months after detonation. A test program will be initiated at that time to determine the degree of reservoir stimulation achieved. (author)

  9. Self-Talk: It Works, but How? Development and Preliminary Validation of the Functions of Self-Talk Questionnaire

    Science.gov (United States)

    Theodorakis, Yannis; Hatzigeorgiadis, Antonis; Chroni, Stiliani

    2008-01-01

    The aim of this investigation was to develop an instrument assessing the functions of self-talk (ST) in sports. Two studies were conducted for the development of the Functions of Self-Talk Questionnaire (FSTQ). In the first study, a prospective instrument was developed based on empirical evidence and a series of preliminary exploratory factor…

  10. Preliminary study of varietal susceptibility to sulfur dioxide

    International Nuclear Information System (INIS)

    The injury response of plants to air pollutants, such as sulfur dioxide, is known to vary in severity and type for different varieties or cultivars of a species. Differences in the susceptibility of soybean varieties to sulfur dioxide have previously been noted, but sufficient information is not available concerning the sulfur dioxide resistance of varieties commonly grown in the Midwest. Results are reported from preliminary experiments concerning acute sulfur dioxide effects on 12 soybean varieties. The injury symptoms ranged from cream colored necrotic lesions (generally on younger leaves) to a reddish brown necrotic stipling (on older leaves). Differences in the severity of symptom development for the varieties was evident on both the younger and older leaves. No injury was apparent with three of the varieties

  11. Preliminary results of the first paleontologic investigations in Uruguayan Antarctica

    International Nuclear Information System (INIS)

    Preliminary results of the first Uruguayan paleontollogic and biostratigraphical investigations in Antartica are presented. The field work was performed in fildes Peninsula, King George Island, near Uruguayan station Base Cientifica Antarctica Artigas.Some fossiliferous outcrops were geologic and paleontologically analyzed, among them Fossil Hills, situated in the center part of the peninsula, in front of Ardley Island, between the chinese and chilean stations.This hill is composed of fossil bearing piroclastic and epiclastic rocks, assigned to the fossil Hill Fm. Vegetal remains(petrified wood and leaf impronts) were observed and collected in this unit and it is remarkable the presence of Nothofagus sp. and invertebrate trace fossils, Cochlichmus isp and Helminthopsis isp.The depositional environment deduced from the fossil association in lacustrine, under a warm and humid climate.In the same deposits, other investigators have collected aquatic and ratite bird trace fossils. Paleontologic evidence is not contradictory with the Eocene age previously proposed for the studied deposits. (author)

  12. Preliminary Results on Lunar Interior Properties from the GRAIL Mission

    Science.gov (United States)

    Williams, James G.; Konopliv, Alexander S.; Asmar, Sami W.; Lemoine, H. Jay; Melosh, H. Jay; Neumann, Gregory A.; Phillips, Roger J.; Smith, David E.; Solomon, Sean C.; Watkins, Michael M.; Wieczorek, Mark A.; Zuber, Maria T.; Andrews-Hanna, Jeffrey C.; Head, James W.; Kiefer, Walter S.; Matsuyama, Isamu; McGovern, Patrick J.; Nimmo, Francis; Weber, Renee C.; Boggs, D. H.; Goossens, Sander J.; Kruizinga, Gerhard L.; Mazarico, Erwan; Park, Ryan S.; Yuan, Dah-Ning

    2013-01-01

    The Gravity Recovery and Interior Laboratory (GRAIL) mission has provided lunar gravity with unprecedented accuracy and resolution. GRAIL has produced a high-resolution map of the lunar gravity field while also determining tidal response. We present the latest gravity field solution and its preliminary implications for the Moon's interior structure, exploring properties such as the mean density, moment of inertia of the solid Moon, and tidal potential Love number k2. Lunar structure includes a thin crust, a deep mantle, a fluid core, and a suspected solid inner core. An accurate Love number mainly improves knowledge of the fluid core and deep mantle. In the future GRAIL will search for evidence of tidal dissipation and a solid inner core.

  13. Microangiographic study of the canine dental tissues: a preliminary report

    International Nuclear Information System (INIS)

    A microangiographic study of the dental tissues was performed on one adult mongrel dog to examine the usefulness of the technique. This preliminary study used 30% wt/vol Micropaque suspension which was perfused into the common carotid arteries. After the complete perfusion, the specimen was fixed into a mixture of 10% buffered neutral formalin solution and 95% ethyl alcohol. The mandibular bone with teeth in situ was decalcified. The specimen was embedded in methyl methacrylate. One mm slab sections were made, and then the microangiographs were made. Adequate filling of arterioles was evident on the microangiographs. This technique is shown to be useful in characterizing the nature of the blood supply to the bone and teeth that might be involved in the pathogenesis of radiation-induced injury in the canine dental and periodontal tissues

  14. Time domain simulations of preliminary breakdown pulses in natural lightning

    CERN Document Server

    Carlson, B E; Bitzer, P; Christian, H

    2016-01-01

    Lightning discharge is a complicated process with relevant physical scales spanning many orders of magnitude. In an effort to understand the electrodynamics of lightning and connect physical properties of the channel to observed behavior, we construct a simulation of charge and current flow on a narrow conducting channel embedded in three-dimensional space with the time domain electric field integral equation, the method of moments, and the thin-wire approximation. The method includes approximate treatment of resistance evolution due to lightning channel heating and the corona sheath of charge surrounding the lightning channel. Focusing our attention on preliminary breakdown in natural lightning by simulating stepwise channel extension with a simplified geometry, our simulation reproduces the broad features observed in data collected with the Huntsville Alabama Marx Meter Array. Some deviations in pulse shape details are evident, suggesting future work focusing on the detailed properties of the stepping mecha...

  15. ERIS: preliminary design phase overview

    Science.gov (United States)

    Kuntschner, Harald; Jochum, Lieselotte; Amico, Paola; Dekker, Johannes K.; Kerber, Florian; Marchetti, Enrico; Accardo, Matteo; Brast, Roland; Brinkmann, Martin; Conzelmann, Ralf D.; Delabre, Bernard A.; Duchateau, Michel; Fedrigo, Enrico; Finger, Gert; Frank, Christoph; Rodriguez, Fernando G.; Klein, Barbara; Knudstrup, Jens; Le Louarn, Miska; Lundin, Lars; Modigliani, Andrea; Müller, Michael; Neeser, Mark; Tordo, Sebastien; Valenti, Elena; Eisenhauer, Frank; Sturm, Eckhard; Feuchtgruber, Helmut; George, Elisabeth M.; Hartl, Michael; Hofmann, Reiner; Huber, Heinrich; Plattner, Markus P.; Schubert, Josef; Tarantik, Karl; Wiezorrek, Erich; Meyer, Michael R.; Quanz, Sascha P.; Glauser, Adrian M.; Weisz, Harald; Esposito, Simone; Xompero, Marco; Agapito, Guido; Antichi, Jacopo; Biliotti, Valdemaro; Bonaglia, Marco; Briguglio, Runa; Carbonaro, Luca; Cresci, Giovanni; Fini, Luca; Pinna, Enrico; Puglisi, Alfio T.; Quirós-Pacheco, Fernando; Riccardi, Armando; Di Rico, Gianluca; Arcidiacono, Carmelo; Dolci, Mauro

    2014-07-01

    The Enhanced Resolution Imager and Spectrograph (ERIS) is the next-generation adaptive optics near-IR imager and spectrograph for the Cassegrain focus of the Very Large Telescope (VLT) Unit Telescope 4, which will soon make full use of the Adaptive Optics Facility (AOF). It is a high-Strehl AO-assisted instrument that will use the Deformable Secondary Mirror (DSM) and the new Laser Guide Star Facility (4LGSF). The project has been approved for construction and has entered its preliminary design phase. ERIS will be constructed in a collaboration including the Max- Planck Institut für Extraterrestrische Physik, the Eidgenössische Technische Hochschule Zürich and the Osservatorio Astrofisico di Arcetri and will offer 1 - 5 μm imaging and 1 - 2.5 μm integral field spectroscopic capabilities with a high Strehl performance. Wavefront sensing can be carried out with an optical high-order NGS Pyramid wavefront sensor, or with a single laser in either an optical low-order NGS mode, or with a near-IR low-order mode sensor. Due to its highly sensitive visible wavefront sensor, and separate near-IR low-order mode, ERIS provides a large sky coverage with its 1' patrol field radius that can even include AO stars embedded in dust-enshrouded environments. As such it will replace, with a much improved single conjugated AO correction, the most scientifically important imaging modes offered by NACO (diffraction limited imaging in the J to M bands, Sparse Aperture Masking and Apodizing Phase Plate (APP) coronagraphy) and the integral field spectroscopy modes of SINFONI, whose instrumental module, SPIFFI, will be upgraded and re-used in ERIS. As part of the SPIFFI upgrade a new higher resolution grating and a science detector replacement are envisaged, as well as PLC driven motors. To accommodate ERIS at the Cassegrain focus, an extension of the telescope back focal length is required, with modifications of the guider arm assembly. In this paper we report on the status of the

  16. Balancing innovation and evidence.

    Science.gov (United States)

    Pilcher, Jobeth W

    2015-01-01

    Nurse educators are encouraged to use evidence to guide their teaching strategies. However, evidence is not always available. How can educators make decisions regarding strategies when data are limited or absent? Where do innovation and creativity fit? How can innovation be balanced with evidence? This article provides a discussion regarding other sources of evidence, such as extrapolations, theories and principles, and collective expertise. Readers are encouraged to review the options and then analyze how they might be applied to innovation in education. PMID:25790361

  17. What is Evidence? (editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2011-06-01

    Full Text Available Lately, I have been pondering what we really mean when we say “evidence based practice”? In LIS, we all know the definitions that have been proposed (Booth 2000, Eldredge 2000, Crumley and Koufogiannakis 2002, and which have not ever really been challenged. But have we ever said explicitly what qualifies as evidence in this model? The underlying assumption seems to be that evidence is research, hence, we are really talking about research-based practice, but we don’t actually use that term.Higgs and Jones (2000 note that evidence is “knowledge derived from a variety of sources that has been subjected to testing and has found to be credible.” The Oxford English Dictionary states that evidence is “something serving as a proof” (OED, 2011. Neither of these definitions of evidence notes that evidence equals research; research is only one form of evidence. It certainly isn’t the only form of evidence – so what, then, constitutes evidence?Rycroff-Malone et al. (2004 state that that in order for evidence based practice to create a broader evidence base in nursing, “the external, scientific and the internal, intuitive” need to be brought together. The external, scientific is what evidence based practice has been focused on, in the form of scientific research, but Rycroff-Malone et al. note that other elements such as clinical experience, patient experience, and information from the local context also need to be considered.In library and information practice, what are the other forms of evidence we need to consider? I propose that while research evidence is of high importance to our profession and knowledge, LIS practitioners need to first of all consider local evidence. Local evidence is found in our working environment and specific to the context in which we carry out our work. It includes such things as our experiences with patrons in particular contexts, and what we observe to work in such situations, assessment of programs

  18. Evidence based practice

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2011-01-01

    Evidence-based practice (EBP) is an influential interdisciplinary movement that originated in medicine as evidence-based medicine (EBM) about 1992. EBP is of considerable interest to library and information science (LIS) because it focuses on a thorough documentation of the basis for the decision...

  19. Evidence Standards and Litigation

    DEFF Research Database (Denmark)

    Guerra, Alice; Luppi, Barbara; Parisi, Francesco

    aspect of the legal system: the evidence standard. We recast the conventional rent-seeking model to consider how alternative evidence standards affect litigation choices. We analyze the interrelation between different evidence standards, the effectiveness of the parties’ efforts, and the merits of the...... case. We study how these factors jointly affect the parties’ litigation expenditures and the selection of cases brought to the courts. The evidence standard has different effects on different types of cases, reducing litigation for high-merit cases when standards are set low and increasing litigation...... for low-merit cases when standards are set high. This provides a valuable key for understanding the sorting effect of evidence standards and their role as a policy instrument in civil litigation....

  20. PROCEDURAL ASPECTS REGARDING REFERENCES FOR PRELIMINARY RULINGS

    Directory of Open Access Journals (Sweden)

    Oana - Măriuca Petrescu

    2008-09-01

    Full Text Available The purpose of preliminary rulings, or the preliminary reference as it is known, can be traced directly to the need to secure uniformity in the Community legal order throughout the Member States. The procedure of preliminary rulings was mentioned for the first time by the Advocate General Joseph-Louis Lagrange 40 years ago in this Opinion in Bosch v de Geus case. Much of the responsibility for applying the rules laid down in the European Community Treaty (EC Treaty and in Community acts belongs to the national courts of the Member States. To help safeguard the uniform application of Community law, article 234 (former art.177 of EC Treaty, therefore lays down a procedure which enables national courts to refer to the European Court of Justice questions of Community law that they have to decide before giving a judgment.

  1. Hydrothermal Liquefaction Treatment Preliminary Hazard Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Lowry, Peter P.; Wagner, Katie A.

    2015-08-31

    A preliminary hazard assessment was completed during February 2015 to evaluate the conceptual design of the modular hydrothermal liquefaction treatment system. The hazard assessment was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. This analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affecting the public.

  2. Development of preliminary Nevada transportation accident characteristics

    International Nuclear Information System (INIS)

    The US DOE, Yucca Mountain Site Characterization Project Office (YMSCPO) has been given the responsibility for characterization of the potential repository site at Yucca Mountain, Nevada, and the analysis of repository-related impacts in the State of Nevada. In support of these responsibilities, the YMSCPO initiated a preliminary study to develop background information on the character of the transportation accidents occurring on the highways and raillines in the State of Nevada. The results of this preliminary study shows that while the transportation accidents in Nevada follow national trends, there are some distinct differences between Nevada and the rest of the Nation. This paper summarizes those results

  3. 15 CFR 270.101 - Preliminary reconnaissance.

    Science.gov (United States)

    2010-01-01

    ... INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NATIONAL CONSTRUCTION SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS Establishment and Deployment of Teams § 270.101 Preliminary reconnaissance. (a) To... the site of a building failure. The Director may establish and deploy a Team to conduct...

  4. Preliminary investigations of piezoelectric based LED luminary

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Andersen, Michael A. E.; Meyer, Kaspar Sinding

    2011-01-01

    This paper presents a preliminary study of PT (Piezoelectric Transformer) based SMPS’s (Switch Mode Power Supplies) for LED luminary. The unique properties of PTs (efficiency, power density and EMI) make them highly suitable for this application. Power stage topologies, rectifiers circuits...

  5. The Adaptation Gap Report - a Preliminary Assessment

    DEFF Research Database (Denmark)

    Alverson, Keith; Olhoff, Anne; Noble, Ian;

    This first Adaptation Gap report provides an equally sobering assessment of the gap between adaptation needs and reality, based on preliminary thinking on how baselines, future goals or targets, and gaps between them might be defined for climate change adaptation. The report focuses on gaps in...... developing countries in three important areas: finance, technology and knowledge....

  6. 25 CFR 11.1005 - Preliminary inquiry.

    Science.gov (United States)

    2010-04-01

    ... ORDER CODE Juvenile Offender Procedure § 11.1005 Preliminary inquiry. (a) If a minor is placed in... purpose of determining: (1) Whether probable cause exist to believe the minor committed the alleged.... (b) If a minor has been released to the parents, guardian or custodian, the children's court...

  7. Hypogeous fungi of Lithuania: a preliminary checklist

    Directory of Open Access Journals (Sweden)

    Ernestas Kutorga

    2013-12-01

    Full Text Available The paper reports on hypogeous fungi known from Lithuania, and data on their habitats, phenology, and distribution. References on the collections kept in the herbaria are also pointed out. The information is based on literature data and re-examination of all available voucher specimens. 22 species (12 genera, 3 phyla recorded from 124 localities are presented in a preliminary checklist.

  8. Hypogeous fungi of Lithuania: a preliminary checklist

    OpenAIRE

    Ernestas Kutorga; Marija Kataržytė

    2013-01-01

    The paper reports on hypogeous fungi known from Lithuania, and data on their habitats, phenology, and distribution. References on the collections kept in the herbaria are also pointed out. The information is based on literature data and re-examination of all available voucher specimens. 22 species (12 genera, 3 phyla) recorded from 124 localities are presented in a preliminary checklist.

  9. 23 CFR 645.109 - Preliminary engineering.

    Science.gov (United States)

    2010-04-01

    ... regularly for the utility in its own work and that the costs are reasonable. (c) The procedures in 23 CFR... 23 Highways 1 2010-04-01 2010-04-01 false Preliminary engineering. 645.109 Section 645.109 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC...

  10. Preliminary aspects of a qualitative research projection

    OpenAIRE

    Simona Haidau

    2012-01-01

    In this paper are presented preliminary aspects on the design of of qualitative research achieved by nongovernmental organizations in the North-East of Romȃnia. The research aims to identify attitudes, opinions and behaviors to nongovernmental organizations to implement public relations programs and campaigns.

  11. Evidence informed decision making

    DEFF Research Database (Denmark)

    Sharma, Tarang; Choudhury, Moni; Kaur, Bindweep;

    2015-01-01

    guidance producing programmes and at all stages of development. CE could range from information from experts and patient/carers, grey literature (including evidence from websites and policy reports) and testimony from stakeholders through consultation. Six tools for critical appraisal of CE were available......OBJECTIVES: Colloquial evidence (CE) has been described as the informal evidence that helps provide context to other forms of evidence in guidance development. Despite challenges around quality, and the potential biases, the use of CE is becoming increasingly important in assessments where...... extracted from all NICE technical and process manuals by two reviewers and quality assured and analyzed by a third reviewer. This was considered in light of the results of a focused literature review and a combined checklist for quality assessment was developed. RESULTS: At NICE, CE is utilised across all...

  12. Gait as evidence

    DEFF Research Database (Denmark)

    Lynnerup, Niels; Larsen, Peter Kastmand

    2014-01-01

    This study examines what in Denmark may constitute evidence based on forensic anthropological gait analyses, in the sense of pointing to a match (or not) between a perpetrator and a suspect, based on video and photographic imagery. Gait and anthropometric measures can be used when direct facial...... comparison is not possible because of perpetrators masking their faces. The nature of judicial and natural scientific forms of evidence is discussed, and rulings dealing with the admissibility of video footage and forensic evidence in general are given. Technical issues of video materials are discussed, and...... the study also discusses how such evidence may be presented, both in written statements and in court. © The Institution of Engineering and Technology 2014....

  13. Evidence-Based Development

    DEFF Research Database (Denmark)

    Hertzum, Morten; Simonsen, Jesper

    2004-01-01

    Systems development is replete with projects that represent substantial resource investments but result in systems that fail to meet users’ needs. Evidence-based development is an emerging idea intended to provide means for managing customer-vendor relationships and working systematically toward...... and electronic patient records for diabetes patients, this paper reports research in progress regarding the prospects and pitfalls of evidence-based development....

  14. Evidence based pediatrics.

    OpenAIRE

    Elizabeta ZISOVSKA

    2015-01-01

    It is very difficult to define the entire phrase “Evidence based pediatrics”, covering all components of this overused sentence. The definition comes out of the common sentence and it means integration of the individual clinical expertize together with the best external clinically available evidence of the systematic reviews which are of interest and benefit of the individual patient.Development of clinically appropriate structured question follows PICO model, i.e. containing f...

  15. Experience with PET FDG - Preliminary analysis

    International Nuclear Information System (INIS)

    Full text: The objective of this preliminary communication was to analyse the indications and data in initial group of patients studied with first dedicated PET scanner in the country at Hospital Militar in Santiago Chile. The main application of positron emission tomography (PET) with 18-Fluoro deoxyglucose (FDG) is related with oncological patients management. We studied 136 patients, 131 (97%) with known or suspected malignant disease and remaining 5 for cardiological or neuropsychiatric disease. Ten patients were controlled diabetics (1 insulin dependent). Their mean age was 51.6±18 years ranging from 6 to 84 years and 65% were females. A total of 177 scans were acquired using a dedicated PET (Siemens HR + with 4mm resolution) system. Mean F18-FDG injected dose was 477±107 MBq (12.9±2.9 mCi). Mean blood glucose levels, performed prior the injection, were 94±17mg/dl (range 62-161). F18-FDG was obtained from the cyclotron IBA Cyclone 18/9 installed in the Chilean Agency of Nuclear Energy, distant about 15 miles away from the clinical PET facility. PET studies were analyzed by at least 4 independent observers visually. Standardized uptake value (SUV) was calculated in some cases. Image fusion of FDG images with recent anatomical (CT, MRI) studies was performed where available. Data acquisition protocol consisted in 7-8 beds/study from head to mid-thighs, with 6-7-min/bed acquisitions, 36% transmission with germanium 68 rods. Data was reconstructed with standard OSEM protocol. The main indications included pulmonary lesions in 31%, gastrointestinal cancers in 21%, melanoma in 13% and lymphoma in 9% patients. The remaining were of breast, thyroid, testes, ovary, musculoskeletal (soft tissue and bone), brain tumour etc. Abnormal focal tracer uptake was observed in 83/131 oncological patients, 54% corroborating with clinical diagnosis of primary tumor or recurrence while 46% showed new metastatic localization. FDG scans were normal 36/131 patients. In 9 patients

  16. 32 CFR 644.30 - Preliminary real estate work.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Preliminary real estate work. 644.30 Section 644... PROPERTY REAL ESTATE HANDBOOK Project Planning Military (army and Air Force) and Other Federal Agencies § 644.30 Preliminary real estate work. (a) Preliminary real estate work is defined as that action...

  17. Preliminary evaluation of timing training accelerator for the SPRINT rowing system

    Directory of Open Access Journals (Sweden)

    Ruffaldi Emanuele

    2011-12-01

    Full Text Available This paper shows the selection and preliminary evaluation of rowing gesture timing training on the SPRINT platform. After the analysis of experts’ gestures and a literature review of rowing technique features, the selection of proper feedbacks and the development of the training protocol are investigated. The general problem discussed here is the learning of timing of complex motor pattern under the effect of load. Eight novice adults participated the experiment, half of them receiving vibrotactile feedback (VIB, both receiving knowledge of results (KR after training blocks. Preliminary results show the difficulty people had to accomplish the task and to exploit feedback. There is in fact no evidence of feedback effectiveness when comparing VIB-KR and KR group. Some causes were hypothesized and a side effect of load condition arisen from data. Therefore timing training will be further investigated exploiting information gathered.

  18. Evidence-based dentistry.

    Science.gov (United States)

    Chambers, David W

    2010-01-01

    Both panegyric and criticism of evidence-based dentistry tend to be clumsy because the concept is poorly defined. This analysis identifies several contributions to the profession that have been made under the EBD banner. Although the concept of clinicians integrating clinical epidemiology, the wisdom of their practices, and patients' values is powerful, its implementation has been distorted by a too heavy emphasis of computerized searches for research findings that meet the standards of academics. Although EBD advocates enjoy sharing anecdotal accounts of mistakes others have made, faulting others is not proof that one's own position is correct. There is no systematic, high-quality evidence that EBD is effective. The metaphor of a three-legged stool (evidence, experience, values, and integration) is used as an organizing principle. "Best evidence" has become a preoccupation among EBD enthusiasts. That overlong but thinly developed leg of the stool is critiqued from the perspectives of the criteria for evidence, the difference between internal and external validity, the relationship between evidence and decision making, the ambiguous meaning of "best," and the role of reasonable doubt. The strongest leg of the stool is clinical experience. Although bias exists in all observations (including searches for evidence), there are simple procedures that can be employed in practice to increase useful and objective evidence there, and there are dangers in delegating policy regarding allowable treatments to external groups. Patient and practitioner values are the shortest leg of the stool. As they are so little recognized, their integration in EBD is problematic and ethical tensions exist where paternalism privileges science over patient's self-determined best interests. Four potential approaches to integration are suggested, recognizing that there is virtually no literature on how the "seat" of the three-legged stool works or should work. It is likely that most dentists

  19. Preliminary evidence of motor impairment among polysubstance 3,4-methylenedioxymethamphetamine users with intact neuropsychological functioning

    OpenAIRE

    Bousman, Chad A.; Cherner, Mariana; Emory, Kristen T; BARRON, DANIEL; Grebenstein, Patricia; Atkinson, J. Hampton; Heaton, Robert K.; Grant, Igor

    2010-01-01

    Neuropsychological disturbances have been reported in association with use of the recreational drug “ecstasy,” or 3,4-methylenedioxymethamphetamine (MDMA), but findings have been inconsistent. We performed comprehensive neuropsychological testing examining seven ability domains in 21 MDMA users (MDMA+) and 21 matched control participants (MDMA−). Among MDMA+ participants, median [interquartile range] lifetime MDMA use was 186 [111, 516] doses, with 120 [35–365] days of abstinence. There were ...

  20. Preliminary evidence that ketamine inhibits spreading depolarizations in acute human brain injury

    DEFF Research Database (Denmark)

    Sakowitz, Oliver W; Kiening, Karl L; Krajewski, Kara L;

    2009-01-01

    inhibited by the noncompetitive N-methyl-d-aspartate receptor antagonist ketamine. This restored electrocorticographic activity. CONCLUSIONS: These anecdotal electrocorticographic findings suggest that ketamine has an inhibitory effect on spreading depolarizations in humans. This is of potential interest...

  1. Neurophysiological correlates of eye movement desensitization and reprocessing sessions: preliminary evidence for traumatic memories integration.

    Science.gov (United States)

    Farina, Benedetto; Imperatori, Claudio; Quintiliani, Maria I; Castelli Gattinara, Paola; Onofri, Antonio; Lepore, Marta; Brunetti, Riccardo; Losurdo, Anna; Testani, Elisa; Della Marca, Giacomo

    2015-11-01

    We have investigated the potential role of eye movement desensitization and reprocessing (EMDR) in enhancing the integration of traumatic memories by measuring EEG coherence, power spectra and autonomic variables before (pre-EMDR) and after (post-EMDR) EMDR sessions during the recall of patient's traumatic memory. Thirteen EMDR sessions of six patients with post-traumatic stress disorder were recorded. EEG analyses were conducted by means of the standardized Low Resolution Electric Tomography (sLORETA) software. Power spectra, EEG coherence and heart rate variability (HRV) were compared between pre- and post-EMDR sessions. After EMDR, we observed a significant increase of alpha power in the left inferior temporal gyrus (T = 3.879; P = 0.041) and an increased EEG coherence in beta band between C3 and T5 electrodes (T = 6.358; P EMDR sessions was also observed (pre-EMDR: 6.38 ± 6.83; post-EMDR: 2.46 ± 2.95; U-Test = 45, P = 0.043). Finally, the values of lagged coherence were negatively associated with subjective units of disturbance (r(24) = -0.44, P EMDR leads to an integration of dissociated aspects of traumatic memories and, consequently, a decrease of hyperarousal symptoms [Correction made here after initial publication]. PMID:25123377

  2. Preliminary evidence for cue-induced alcohol craving modulated by serotonin transporter gene polymorphism rs1042173

    Directory of Open Access Journals (Sweden)

    Nassima eAit-Daoud

    2012-02-01

    Full Text Available We previously have shown that cue-induced alcohol craving and propensity for higher drinking are modulated by allelic differences in SLC6A4. In an independent study, we characterized a functional polymorphism, rs1042173 (G/T, in the SLC6A4 3′-untranslated region (3′-UTR; the T allele was associated with lower mRNA and protein levels, and the alcohol-dependent (AD individuals carrying the TT genotype showed higher drinking intensity compared with G-allele carriers. Building upon these findings, we hypothesized that the low-expressing TT genotype associated with intense drinking would predict higher craving for alcohol in AD individuals. In this pilot study, we sought to test our hypothesis by examining 34 Hispanic AD volunteers (mean age, 34.8 years for rs1042173 genotype-based (i.e., TT vs. TG/GG (Gx differences in subjective response to alcohol. We employed a human laboratory paradigm and analyzed the data using a linear mixed-effects model to assess treatment, cue procedures, and genotype main effects as well as the two-way interaction effects between them. On subjective urge to drink and crave for a drink, we found a significant main effect of the cue experiment (p ≤ 0.01 and an interaction effect between genotype and cue effects (p < 0.05. TT genotype was associated with higher intensity of drinking and craving for alcohol. Our results not only support the hypothesis that rs1042173 is a genetic marker for cue-induced alcohol craving among AD males but also are suggestive of a neurobiological mechanism associated with the rs1042173-TT genotype that triggers a disproportionate craving in response to alcohol consumption, which in turn may lead to more intense drinking. Future studies with larger sample sizes are needed to characterize the interactive effects of the serotonin transporter-linked polymorphic region (5′-HTTLPR-L-allele reported in our previous study and of the rs1042173-TT genotype on cue-induced alcohol craving.

  3. "Wesley says": a children's response inhibition playground training game yields preliminary evidence of transfer effects.

    Science.gov (United States)

    Zhao, Xin; Chen, Ling; Fu, Lily; Maes, Joseph H R

    2015-01-01

    Recent studies suggest that the response inhibition ability of children can be modified through training. Based on the notion of embodied cognition, we investigated transfer effects of a 7-day training program using a game named "Wesley says" in 8- to 12-year-old children (n = 15). The game consists of providing commands for performing simple body actions, the actual execution of which is conditional upon the preceding verbal expression "Wesley says." Training effects were assessed with a computer-based visual go/no-go task and the Stroop color-word interference task. Relative to a control group playing other games mainly involving physical exercise (n = 15), the trained group showed a performance improvement on the go/no-go task, but not on the Stroop task. These results suggest the potential of an easy-to-use and ecologically valid training game to improve the inhibition capacity of children on related response inhibition tasks but not on tasks measuring other aspects of inhibition, such as interference control. PMID:25762970

  4. "Wesley says": A children's response inhibition playground training game yields preliminary evidence of transfer effects

    NARCIS (Netherlands)

    Zhao, X.; Chen, L.; Fu, L.; Maes, J.H.R.

    2015-01-01

    Recent studies suggest that the response inhibition ability of children can be modified through training. Based on the notion of embodied cognition, we investigated transfer effects of a 7-day training program using a game named "Wesley says" in 8- to 12-year-old children (n = 15). The game consists

  5. "Wesley says": A children's response inhibition playground training game yields preliminary evidence of transfer effects

    OpenAIRE

    Zhao, Xin; Chen, Ling; Fu, Lily; Maes, Joseph H. R.

    2015-01-01

    Recent studies suggest that the response inhibition ability of children can be modified through training. Based on the notion of embodied cognition, we investigated transfer effects of a 7-day training program using a game named “Wesley says” in 8- to 12-year-old children (n = 15). The game consists of providing commands for performing simple body actions, the actual execution of which is conditional upon the preceding verbal expression “Wesley says.” Training effects were assessed with a com...

  6. Outsourcing of Internal Audit Services in Australian Firms: Some Preliminary Evidence

    OpenAIRE

    Divesh S. Sharma; Nava Subramaniam

    2005-01-01

    Although internal auditing (IA) services have been traditionally performed in-house, organizations are increasingly outsourcing such services. Using a Transaction Cost Economics (TCE) perspective, this study examined the influence of several organizational-level variables on the decision to outsource or in-house their internal audit functions. The study also identified the type of IA services that were likely to be out-sourced rather than in-housed, the extent to which incumbent external fina...

  7. Preliminary evidence for performance enhancement following parietal lobe stimulation in Developmental Dyscalculia

    OpenAIRE

    Iuculano, Teresa; Cohen Kadosh, Roi

    2014-01-01

    Nearly 7% of the population exhibit difficulties in dealing with numbers and performing arithmetic, a condition named Developmental Dyscalculia (DD), which significantly affects the educational and professional outcomes of these individuals, as it often persists into adulthood. Research has mainly focused on behavioral rehabilitation, while little is known about performance changes and neuroplasticity induced by the concurrent application of brain-behavioral approaches. It has been shown that...

  8. Preliminary evidence for performance enhancement following parietal lobe stimulation in Developmental Dyscalculia.

    Science.gov (United States)

    Iuculano, Teresa; Cohen Kadosh, Roi

    2014-01-01

    Nearly 7% of the population exhibit difficulties in dealing with numbers and performing arithmetic, a condition named Developmental Dyscalculia (DD), which significantly affects the educational and professional outcomes of these individuals, as it often persists into adulthood. Research has mainly focused on behavioral rehabilitation, while little is known about performance changes and neuroplasticity induced by the concurrent application of brain-behavioral approaches. It has been shown that numerical proficiency can be enhanced by applying a small-yet constant-current through the brain, a non-invasive technique named transcranial electrical stimulation (tES). Here we combined a numerical learning paradigm with transcranial direct current stimulation (tDCS) in two adults with DD to assess the potential benefits of this methodology to remediate their numerical difficulties. Subjects learned to associate artificial symbols to numerical quantities within the context of a trial and error paradigm, while tDCS was applied to the posterior parietal cortex (PPC). The first subject (DD1) received anodal stimulation to the right PPC and cathodal stimulation to the left PPC, which has been associated with numerical performance's improvements in healthy subjects. The second subject (DD2) received anodal stimulation to the left PPC and cathodal stimulation to the right PPC, which has been shown to impair numerical performance in healthy subjects. We examined two indices of numerical proficiency: (i) automaticity of number processing; and (ii) mapping of numbers onto space. Our results are opposite to previous findings with non-dyscalculic subjects. Only anodal stimulation to the left PPC improved both indices of numerical proficiency. These initial results represent an important step to inform the rehabilitation of developmental learning disabilities, and have relevant applications for basic and applied research in cognitive neuroscience, rehabilitation, and education. PMID:24570659

  9. Preliminary evidence for performance enhancement following parietal lobe stimulation in Developmental Dyscalculia

    Directory of Open Access Journals (Sweden)

    Teresa Iuculano

    2014-02-01

    Full Text Available Nearly 7% of the population exhibit difficulties in dealing with numbers and performing arithmetic, a condition named Developmental Dyscalculia (DD, which significantly affects the educational and professional outcomes of these individuals, as it often persists into adulthood. Research has mainly focused on behavioral rehabilitation, while little is known about performance changes and neuroplasticity induced by the concurrent application of brain-behavioral approaches. It has been shown that numerical proficiency can be enhanced by applying a small – yet constant – current through the brain, a non-invasive technique named transcranial electrical stimulation (tES. Here we combined a numerical learning paradigm with transcranial direct current stimulation (tDCS in two adults with DD to assess the potential benefits of this methodology to remediate their numerical difficulties. Subjects learned to associate artificial symbols to numerical quantities within the context of a trial and error paradigm, while tDCS was applied to the posterior parietal cortex (PPC. The first subject (DD1 received anodal stimulation to the right PPC and cathodal stimulation to the left PPC, which has been associated with numerical performance’s improvements in healthy subjects. The second subject (DD2 received anodal stimulation to the left PPC and cathodal stimulation to the right PPC, which has been shown to impair numerical performance in healthy subjects. We examined two indices of numerical proficiency: (i automaticity of number processing; and (ii mapping of numbers onto space. Our results are opposite to previous findings with non-dyscalculic subjects. Only anodal stimulation to the left PPC improved both indices of numerical proficiency. These initial results represent an important step to inform the rehabilitation of developmental learning disabilities, and have relevant applications for basic and applied research in cognitive neuroscience, rehabilitation, and education.

  10. Divestments in Banking. Preliminary Evidence on the Role of External Factors

    Directory of Open Access Journals (Sweden)

    Krzysztof Jackowicz

    2011-06-01

    Full Text Available Divestment constitutes an important method of corporate restructuring. Despite this fact, the banking literature on divestment is very limited. In this text, we try to remediate partially to the shortcomings of the existing literature by examining empirically the role of external factors. Using a large sample of 313 transactions, we have established that parent companies originate from countries with relatively high accumulated wealth, slow GDP growth, stable macroeconomic situation and dominant bank intermediation in financial system. The acquirers in turn come from poorer countries with faster economic growth and relatively more market-oriented financial systems. Those results broadly conform with the predictions of three hypotheses formulated in the text, namely the weak performance hypothesis, the corporate governance hypothesis and the rebalancing hypothesis.

  11. Preliminary Evidence that Self-Efficacy Predicts Physical Activity in Multiple Sclerosis

    Science.gov (United States)

    Motl, Robert W.; McAuley, Edward; Doerksen, Shawna; Hu, Liang; Morris, Katherine S.

    2009-01-01

    Individuals with multiple sclerosis (MS) are less physically active than nondiseased people. One method for increasing physical activity levels involves the identification of factors that correlate with physical activity and that are modifiable by a well designed intervention. This study examined two types of self-efficacy as cross-sectional and…

  12. Symptom Cluster and Quality of Life: Preliminary Evidence in Multiple Sclerosis

    OpenAIRE

    Motl, Robert W.; McAuley, Edward

    2010-01-01

    The present study examined the symptom cluster of fatigue, pain, and depression as a correlate of reduced quality of life (QOL) in individuals with multiple sclerosis (MS). The sample included 291 individuals with a definite diagnosis of MS who were enrolled in a 6-month longitudinal study of physical activity and QOL. The participants completed baseline measures of fatigue, depression, and pain and follow-up measures of QOL. Cluster analysis initially identified three sub-groups differing in...

  13. Preliminary evidence for progressive sestonic food depletion in incoming tide over a broad tidal sand flat

    Science.gov (United States)

    Peterson, Charles H.; Black, Robert

    1991-04-01

    Sequential sampling of a water mass flooding over a broad intertidal sand flat at Shark Bay, Western Australia demonstrated a pattern of progressively declining chlorophyll concentrations. After 3 h 25 min of movement up over the intertidal flat, the already low concentration (0·06 μg l -1) of chlorophyll a had declined by 25%. If representative of average conditions, this observed rate of sestonic food depletion, when combined with reductions in feeding time during low tide, would predict a 59% lower growth for mid-intertidal vs. subtidal suspension-feeding bivalves. Previously published reductions in bivalve growth with increased elevation at this site are not much larger (57, 61, 86 and 92%) than predicted, implying that food depletion in incoming tides may help constrain growth of suspension feeders on broad intertidal sand flats.

  14. Body guilt: Preliminary evidence for a further subjective experience of self-objectification

    OpenAIRE

    Calogero, Rachel M.; Pina, Afroditi

    2011-01-01

    Two studies investigated body guilt (i.e., feeling regret and remorse over how the body looks and a desire for reparative action to “fix” the body) within the framework of objectification theory among predominantly White British undergraduate women. In Study 1 (N = 225), participants completed self-report measures of interpersonal sexual objectification, self-surveillance, body shame, body guilt, and eating restraint. Path analyses indicated support for the inclusion of body guilt in the obje...

  15. Body Guilt: Preliminary Evidence for a Further Subjective Experience of Self-Objectification

    Science.gov (United States)

    Calogero, Rachel M.; Pina, Afroditi

    2011-01-01

    Two studies investigated body guilt (i.e., feeling regret and remorse over how the body looks and a desire for reparative action to "fix" the body) within the framework of objectification theory among predominantly White British undergraduate women. In Study 1 (N = 225), participants completed self-report measures of interpersonal sexual…

  16. The Role of Political Information in Union Certification Elections: Preliminary Evidence from Selected States

    Directory of Open Access Journals (Sweden)

    Michael Toma

    2005-12-01

    Full Text Available This paper focuses a public choice lens on the rationality of voters in U.S. union certification elections in fourteen selected states between 1994 and 2001. These elections are characterized by conditions that are favorable for empirical tests of the rational voter model. The electorates are relatively small, the potential benefits can be significant, and the costs of voting are negligible. The empirical work yields three straightforward results. First, voter participation is negatively related to the size of the electorate. Second, the margin of victory is negatively related to the voter participation rate. Third, as the political climate becomes more liberal, the voter participation rate declines. This suggests that in labor-friendly states, there is less of an incentive to vote either for or against certifying a union to collective bargain on behalf of workers.

  17. MMPI-2: Cluster Analysis of Personality Profiles in Perinatal Depression—Preliminary Evidence

    Directory of Open Access Journals (Sweden)

    Valentina Meuti

    2014-01-01

    Full Text Available Background. To assess personality characteristics of women who develop perinatal depression. Methods. The study started with a screening of a sample of 453 women in their third trimester of pregnancy, to which was administered a survey data form, the Edinburgh Postnatal Depression Scale (EPDS and the Minnesota Multiphasic Personality Inventory 2 (MMPI-2. A clinical group of subjects with perinatal depression (PND, 55 subjects was selected; clinical and validity scales of MMPI-2 were used as predictors in hierarchical cluster analysis carried out. Results. The analysis identified three clusters of personality profile: two “clinical” clusters (1 and 3 and an “apparently common” one (cluster 2. The first cluster (39.5% collects structures of personality with prevalent obsessive or dependent functioning tending to develop a “psychasthenic” depression; the third cluster (13.95% includes women with prevalent borderline functioning tending to develop “dysphoric” depression; the second cluster (46.5% shows a normal profile with a “defensive” attitude, probably due to the presence of defense mechanisms or to the fear of stigma. Conclusion. Characteristics of personality have a key role in clinical manifestations of perinatal depression; it is important to detect them to identify mothers at risk and to plan targeted therapeutic interventions.

  18. Preliminary evidence for 17 coastal terraces on Fildes Peninsula, King George Island, Antarctica

    Institute of Scientific and Technical Information of China (English)

    CHU Zhuding; YIN Xuebin; SUN Liguang; WANG Yuhong

    2015-01-01

    This study confirms the presence of 17 coastal terraces on Fildes Peninsula, Antarctica based on field observations and grain size analysis. The terraces formed by isostatic uplift during climate warming and glacier melting, and each level corresponds to a relatively stable period of climate. The grain size characteristics indicate an overlapping sedimentary origin for the sediments on the coastal terraces. The consistency of regional sea level rise, climate change, and glacial area suggest the presence of similar coastal terraces on King George Island since 18.0 ka.

  19. Preliminary Evidence on the Effectiveness of Psychological Treatments Delivered at a University Counseling Center

    Science.gov (United States)

    Minami, Takuya; Davies, D. Robert; Tierney, Sandra Callen; Bettmann, Joanna E.; McAward, Scott M.; Averill, Lynnette A.; Huebner, Lois A.; Weitzman, Lauren M.; Benbrook, Amy R.; Serlin, Ronald C.; Wampold, Bruce E.

    2009-01-01

    Treatment data from a university counseling center (UCC) that utilized the Outcome Questionnaire-45.2 (OQ-45; M. J. Lambert et al., 2004), a self-report general clinical symptom measure, was compared against treatment efficacy benchmarks from clinical trials of adult major depression that utilized similar measures. Statistical analyses suggested…

  20. MMPI-2: Cluster Analysis of Personality Profiles in Perinatal Depression—Preliminary Evidence

    OpenAIRE

    2014-01-01

    Background. To assess personality characteristics of women who develop perinatal depression. Methods. The study started with a screening of a sample of 453 women in their third trimester of pregnancy, to which was administered a survey data form, the Edinburgh Postnatal Depression Scale (EPDS) and the Minnesota Multiphasic Personality Inventory 2 (MMPI-2). A clinical group of subjects with perinatal depression (PND, 55 subjects) was selected; clinical and validity scales of MMPI-2 were used a...

  1. Pickles and ice cream! Food cravings in pregnancy: hypotheses, preliminary evidence, and directions for future research

    OpenAIRE

    Orloff, Natalia C.; Hormes, Julia M.

    2014-01-01

    Women in the United States experience an increase in food cravings at two specific times during their life, (1) perimenstrually and (2) prenatally. The prevalence of excess gestational weight gain (GWG) is a growing concern due to its association with adverse health outcomes in both mothers and children. To the extent that prenatal food cravings may be a determinant of energy intake in pregnancy, a better understanding of craving etiology could be crucial in addressing the issue of excessive ...

  2. Preliminary evidence for a Hercynian age of the Versoyen complex, western Alps

    International Nuclear Information System (INIS)

    To date the magmatic event that generated the Versoyen mafic complex, four fractions of zircon from a cross-cutting leuco-gabbro dike, has been analyzed by the U-Pb method, defining a regression line that intercepts the concordia curve at 309 ± 6 (2 σ) Ma and 3 240 ± 34 Ma. These two ages can be interpreted to date, respectively, emplacement of the leuco-gabbro into the Versoyen complex, and the age of inherited Archean zircon cores, present in the newly formed crystals. The age of 309 Ma suggests that both Versoyen mafic magmatism and subsequent eclogite facies metamorphism belong to the Hercynian, and not the Alpine orogenic cycle. (authors)

  3. Articulatory Changes Following Treatment of Muscle Tension Dysphonia: Preliminary Acoustic Evidence

    Science.gov (United States)

    Dromey, Christopher; Nissen, Shawn L.; Roy, Nelson; Merrill, Ray M.

    2008-01-01

    Purpose: Primary muscle tension dysphonia (MTD), a voice disturbance that occurs in the absence of structural or neurological pathology, may respond to manual circumlaryngeal techniques, which ostensibly alter the posture of the larynx and/or the configuration of the vocal folds without directly targeting supralaryngeal articulatory structures.…

  4. Oppositional Defiant Disorder Rating Scale: Preliminary Evidence of Reliability and Validity

    Science.gov (United States)

    Hommersen, Paul; Murray, Candice; Ohan, Jeneva L.; Johnston, Charlotte

    2006-01-01

    In this article, the authors report the psychometric properties of a parent-completed rating scale based on the criteria for oppositional defiant disorder (ODD) in the "Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition-Text Revision" ("DSM-IV-TR"). Mothers of 294 boys and 48 girls with attention-deficit/hyperactivity disorder…

  5. Measures of Hindu Pathways: Development and Preliminary Evidence of Reliability and Validity.

    Science.gov (United States)

    Tarakeshwar, Nalini; Pargament, Kenneth I.; Mahoney, Annette

    2003-01-01

    Examines religious practices of Hindus in the United States and develops measures of their religious pathways. Four religious pathways were identified: devotion, ethical action, knowledge, and physical restraint/yoga. Results indicate that the measures of the religious pathways possessed adequate psychometric properties and were predictive of…

  6. Investigating the Governmental Accounting Reform of Greek National Health System (ESY): Some preliminary Evidence

    OpenAIRE

    FILIPPOS STAMATIADIS, Mr

    2009-01-01

    During the last decades, several countries worldwide have introduced financial management reforms as an important part of the New Public Management (NPM) initiative at one or more levels of government sector, by replacing or transforming their traditional budgetary cash accounting systems towards business-like accrual accounting. Following the example of this upcoming managerial trend, the Greek government introduced in 1997 an accrual based accounting system (ABAS) and double-entry book-keep...

  7. Preliminary evidences on SIT application against Aedes albopictus Skuse in Italy

    International Nuclear Information System (INIS)

    Aedes albopictus (Skuse), the Asian Tiger Mosquito, has invaded several countries, during the last years, mainly due to the passive transportation in used tires. In Europe the species firstly arrived in Albany in 1979, then in Italy in 1990, in France in 1999 (Schaffner and Karch 1999), in Belgium in 2000, in Montenegro in 2001. Other countries have already been colonised or are under colonisation in Africa and the Americas. In Italy the colonisation process appears to be very quick mainly due to the passive transportation of adults inside vehicles, to be currently found in seven regions. In its original distribution, Ae. albopictus is known to be a very important vector of many arboviruses including yellow fever and dengue. Moreover it is also capable of transmitting indigenous arboviruses in newly colonised areas, as well as filariasis (Dirofilaria immitis Leidy and D. repens Railleiet and Henry) and other arboviruses like Sindbis, Chikungunya, West Nile and Rift Valley. Finally this species can also cause severe annoyance because of its anthropophily and painful bite. The species is mainly exploiting man-made containers showing an urban and periurban distribution. This 'island' distribution and the low active dispersal capability make it possible considering as convenient the application of SIT as a component of the IPM programmes already implemented. In 1999 we therefore started a project financed with local funds in order to investigate the feasibility of SIT application against Ae. albopictus in Italy

  8. Binge eating disorder and obesity: preliminary evidence for distinct cardiovascular and psychological phenotypes.

    Science.gov (United States)

    Klatzkin, Rebecca R; Gaffney, Sierra; Cyrus, Kathryn; Bigus, Elizabeth; Brownley, Kimberly A

    2015-04-01

    This study investigated cardiovascular functioning, mood, and eating-related psychological factors at rest and in response to mental stress in three groups of women: 1) Obese women with binge eating disorder (BED; n=9); 2) obese non-BED women (n=15); and 3) normal weight (NW) non-BED women (n=15). Compared to both obese and NW non-BED women, obese women with BED showed heightened overall blood pressure and reported greater depression symptoms, perceived stress, and eating-related psychopathology. Additionally, obese women with BED reported greater overall negative affect and state anxiety compared to obese non-BED women. The heart rate response to stress was blunted in the obese BED group compared to the other groups, but this effect was no longer significant after controlling for baseline differences in depression. Correlational analyses revealed a positive association between stress-induced changes in hunger and cardiovascular measures only in obese women with BED. Longitudinal studies are needed to determine if stress dysregulation and stress-induced increases in hunger contribute to the onset and/or maintenance of BED. In particular, studies utilizing an additional NW BED control group are warranted in order to further examine the impact of BED above and beyond the impact of obesity on psychophysiological functioning and to inform the growing literature regarding stress-related factors that distinguish the BED and obesity phenotypes. PMID:25600469

  9. The Meriden School Climate Survey-Student Version: Preliminary Evidence of Reliability and Validity

    Science.gov (United States)

    Gage, Nicholas A.; Larson, Alvin; Chafouleas, Sandra M.

    2016-01-01

    School climate has been linked with myriad positive student outcomes and the measurement of school climate is widely advocated at the national and state level. However, districts have little guidance about how to define and measure school climate. This study examines the psychometric properties of a district-developed school climate measure that…

  10. Preliminary Evidence for the Amplification of Global Warming in Shallow, Intertidal Estuarine Waters

    Science.gov (United States)

    Over the past 50 years, mean annual water temperature in northeastern U.S. estuaries has increased by approximately 1.2°C, with most of the warming recorded in the winter and early spring. We hypothesize that this warming may be amplified in the shallow (<2m), nearshore portions ...

  11. The Effects of Paleoclimatic Events on Mediterranean Trout: Preliminary Evidences from Ancient DNA

    Science.gov (United States)

    Giovannotti, Massimo; Negri, Alessandra; Ruggeri, Paolo; Olivieri, Luigi; Nisi Cerioni, Paola; Lorenzoni, Massimo; Caputo Barucchi, Vincenzo

    2016-01-01

    In this pilot study for the first time, ancient DNA has been extracted from bone remains of Salmo trutta. These samples were from a stratigraphic succession located in a coastal cave of Calabria (southern Italy) inhabited by humans from upper Palaeolithic to historical times. Seven pairs of primers were used to PCR-amplify and sequence from 128 to 410 bp of the mtDNA control region of eleven samples. Three haplotypes were observed: two (ADcs-1 and MEcs-1) already described in rivers from the Italian peninsula; one (ATcs-33) belonging to the southern Atlantic clade of the AT Salmo trutta mtDNA lineage (sensu Bernatchez). The prehistoric occurrence of this latter haplotype in the water courses of the Italian peninsula has been detected for the first time in this study. Finally, we observed a correspondence between frequency of trout remains and variation in haplotype diversity that we related with ecological and demographic changes resulting from a period of rapid cooling known as the Younger Dryas. PMID:27331397

  12. Preliminary Evidence for a Classroom Based Psychosocial Intervention for Disaster Exposed Children with Posttraumatic Stress Symptomatology

    DEFF Research Database (Denmark)

    Elklit, Ask; Rønholt, Stine; Karsberg, Sidsel

    2013-01-01

    the three DSM-IV PTSD symptom clusters. The children were screened for PTSD symptoms at baseline and 1 month after treatment using Darryl. Results There was a statistically significant reduction in PTSD symptoms from pretreatment to post-treatment. Furthermore, a logistic regression analysis revealed...... symptoms. Furthermore, the results indicated that the Darryl instrument is a useful screening tool for assessing PTSD symptoms in this sample of children. Keywords Trauma Disaster Treatment Children Assessment...

  13. Preliminary Evidence for a Classroom Based Psychosocial Intervention for Disaster Exposed Children with Posttraumatic Stress Symptomatology

    Science.gov (United States)

    Rønholt, Stine; Karsberg, Sidsel; Elklit, Ask

    2013-01-01

    Background: In 2004, a firework factory in a residential area of a large Danish city exploded. The children at the local school were screened for symptoms of posttraumatic stress disorder (PTSD) 16 months and 3½ years after the incident. A large proportion of the children still suffered from a substantial number of symptoms 3½ years after the…

  14. Food cravings in pregnancy: Preliminary evidence for a role in excess gestational weight gain.

    Science.gov (United States)

    Orloff, Natalia C; Flammer, Amy; Hartnett, Josette; Liquorman, Sarah; Samelson, Renee; Hormes, Julia M

    2016-10-01

    Currently, more than 50% of American women gain an excessive amount of weight during pregnancy as per guidelines established by the Institute of Medicine and American Congress of Obstetrics and Gynecology. This excess gestational weight gain (GWG) is associated with health complications in both mothers and children. This study sought to examine the hypothesized causal role of cravings in excess GWG. Pregnant women were recruited from a local hospital (n = 40) and via posts on pregnancy-related websites (n = 43). Weight (current and pregravid) and height data were collected to calculate body mass index (BMI) and recommended versus excess GWG. Participants completed the Food Craving Inventory (FCI), which quantifies "frequency" of cravings for specific foods and the likelihood of "giving in" to these cravings. Overweight/obesity prior to pregnancy was reported by 40.5%-57.9% of participants. At the time of survey completion, 19.5% of online and 31.6% of hospital respondents had gained more than the recommended amount of weight for their stage of gestation. All women had experienced and given in to at least one craving, with cravings for "sweets" and "fast foods" being most common. Craving "frequency" accounted for a substantial portion of variance in excess GWG (25.0% in the online sample and 32.0% in respondents recruited at the hospital). Frequency of "giving in" to cravings accounted for 35.0% of the variance in excess GWG in the online sample only. Findings suggest that both craving frequency and consumption of craved foods may increase risk of excess GWG, providing support for the development of interventions targeting cravings in pregnancy as potentially modifiable determinants of energy intake. PMID:27215835

  15. Preliminary Compositional Evidence of Provenance of Ceramics from Hatahara Archaeological Site, Central Amazonia

    Directory of Open Access Journals (Sweden)

    K. P. Nunes

    2013-01-01

    Full Text Available One hundred twenty four ceramic fragments and six clay samples from the Hatahara archaeological site in Amazonas state, Brazil, were analyzed using instrumental neutron activation analysis, INAA, to determine the concentration of twenty chemical elements: Ce, Co, Cr, Cs, Eu, Fe, Hf, K, La, Lu, Na, Nd, Rb, Sc, Ta, Tb, Th, U, Yb, and Zn. The dataset was submitted to multivariate statistical analysis. The classification was done by cluster analysis and discriminant analysis. The results demonstrated the occurrence of four different groups of ceramics, which represent three archaeological phases: Paredão, Manacapuru, and Guarita. This data is consistent with previous traditional petrographic examination of the ceramic samples. Based on probability measures, the great majority of the ceramics are considered to be local in origin.

  16. Assessing Critical Thinking in Higher Education: The HEIghten™ Approach and Preliminary Validity Evidence

    Science.gov (United States)

    Liu, Ou Lydia; Mao, Liyang; Frankel, Lois; Xu, Jun

    2016-01-01

    Critical thinking is a learning outcome highly valued by higher education institutions and the workforce. The Educational Testing Service (ETS) has designed a next generation assessment, the HEIghten™ critical thinking assessment, to measure students' critical thinking skills in analytical and synthetic dimensions. This paper introduces the…

  17. Polarisation of equine pregnancy outcome associated with a maternal MHC class I allele: Preliminary evidence.

    Science.gov (United States)

    Kydd, J H; Case, R; Winton, C; MacRae, S; Sharp, E; Ricketts, S L; Rash, N; Newton, J R

    2016-05-30

    Identification of risk factors which are associated with severe clinical signs can assist in the management of disease outbreaks and indicate future research areas. Pregnancy loss during late gestation in the mare compromises welfare, reduces fecundity and has financial implications for horse owners. This retrospective study focussed on the identification of risk factors associated with pregnancy loss among 46 Thoroughbred mares on a single British stud farm, with some but not all losses involving equid herpesvirus-1 (EHV-1) infection. In a sub-group of 30 mares, association between pregnancy loss and the presence of five common Thoroughbred horse haplotypes of the equine Major Histocompatibility Complex (MHC) was assessed. This involved development of sequence specific, reverse transcriptase polymerase chain reactions and in several mares, measurement of cytotoxic T lymphocyte activity. Of the 46 mares, 10 suffered late gestation pregnancy loss or neonatal foal death, five of which were EHV-1 positive. Maternal factors including age, parity, number of EHV-1 specific vaccinations and the number of days between final vaccination and foaling or abortion were not significantly associated with pregnancy loss. In contrast, a statistically significant association between the presence of the MHC class I B2 allele and pregnancy loss was identified, regardless of the fetus/foal's EHV-1 status (p=0.002). In conclusion, this study demonstrated a significantly positive association between pregnancy loss in Thoroughbred mares and a specific MHC class I allele in the mother. This association requires independent validation and further investigation of the mechanism by which the mare's genetic background contributes to pregnancy outcome. PMID:27139027

  18. Preliminary evidence for a postsynaptic action of beta-bungarotoxin in mammalian skeletal muscle

    Science.gov (United States)

    Storella, R. J.; Schouchoff, A. L.; Fujii, M.; Hill, J.; Fletcher, J. E.; Jiang, M. S.; Smith, L. A.

    1992-01-01

    Two hours after treatment with beta-bungarotoxin (0.34-0.4 microM), when there was complete neuromuscular block, the peak contracture response to 50 microM succinylcholine was significantly reduced by about 35% in the mouse phrenic nerve-diaphragm preparation. Additionally, significant phospholipase A2 activity was detected on primary cell cultures from skeletal muscle which were incubated for 2 hr with concentrations of beta-bungarotoxin greater than or equal to 0.1 microM. Thus, beta-bungarotoxin appears to have pharmacologically and biochemically detectable postsynaptic actions in mammalian muscle systems.

  19. Attentional Dissociation in Hypnosis And Neural Connectivity: Preliminary Evidence from Bilateral Electrodermal Activity.

    Science.gov (United States)

    Bob, Petr; Siroka, Ivana

    2016-01-01

    According to recent findings, interhemispheric interactions and information connectivity represent crucial mechanisms used in processing information across various sensory modalities. To study these interactions, the authors measured bilateral electrodermal activity (EDA) in 33 psychiatric outpatients. The results show that, during congruent Stroop stimuli in hypnosis, the patients with higher hypnotizability manifest a decreased level of interhemispheric information transfer measured by pointwise transinformation (PTI) that was calculated from left and right EDA records. These results show that specific shifts of attentional focus during hypnosis are related to changes of interhemispheric interactions that may be reflected in neural connectivity calculated from the bilateral EDA measurement. This attentional shift may cause dissociated attentional control disturbing integrative functions of consciousness and contextual experiences. PMID:27267677

  20. EVIDENCE OF A GUADALUPIAN AGE FOR THE KHUFF FORMATION OF SOUTHEASTERN OMAN: PRELIMINARY REPORT

    Directory of Open Access Journals (Sweden)

    LUCIA ANGIOLINI

    1998-11-01

    Full Text Available The Guadalupian succession of the Huqf area (Sultanate of Oman represents a mega-sequence comprising the fluvial terrigenous Gharif Formation and the overlying marine Khuff Formation. The Khuff Fm. is subdivided into four members and is composed of marls and bioclastic limestones. The Khuff Fm. yields a rich fauna of brachiopods, conodonts, foraminifers, bivalves, gastropods, ostracods and cephalopods. The brachiopod fauna of the Khuff Fm. includes strophomenids, productids, orthids and terebratulids. The associated conodont fauna includes Hindeodus excavatus Behnken, Merrilina sp., M. praedivergens Kozur & Mostler, and Sweetina n. sp. (systematic descriptions of conodonts are given in the Paleontological Appendix. Foraminifers are represented by species of Miliolina and Rotaliina. The Khuff Fm. is given a Wordian age, based on brachiopods and conodonts. The depositional environment of the Khuff Fm. of southeastern Oman corresponds to the outer shelf of a large carbonate platform covering most of the Arabian Platform. The Khuff Fm. is interpreted as a major transgressive-regressive cycle related to differential subsidence. 

  1. Association between virtues and posttraumatic growth: preliminary evidence from a Chinese community sample after earthquakes

    Directory of Open Access Journals (Sweden)

    Wenjie Duan

    2015-04-01

    Full Text Available Objective. Relationship, vitality, and conscientiousness are three fundamental virtues that have been recently identified as important individual differences to health, well being, and positive development. This cross-sectional study attempted to explore the relationship between the three constructs and post-traumatic growth (PTG in three directions, including indirect trauma samples without post-traumatic stress disorder (PTSD, direct trauma samples without PTSD, and direct trauma samples with PTSD. Methods. A total of 340 community participants from Sichuan Province, Mainland China involved in the study, most of which experienced Wenchuan and Lushan Earthquake. Participants were required to complete the self-reported questionnaire packages at one time point for obtaining their scores on virtues (Chinese Virtues Questionnaire, PTSD (PTSD Checklist-Specific, and PTG (Post-traumatic Growth Inventory-Chinese. Results. Significant and positive correlations between the three virtues and PTG were identified (r = .39–.56; p < .01. Further regression analysis by stepwise method reveled that: in the indirect trauma samples, vitality explained 32% variance of PTG. In reference to the direct trauma sample without PTSD, both relationship and conscientiousness explained 32% variance of PTG, whereas in the direct trauma sample with PTSD, only conscientiousness accounted for 31% the variance in PTG. Conclusion.This cross-sectional investigation partly revealed the roles of different virtues in trauma context. Findings suggest important implications for strengths-based treatment.

  2. INTERNAL AUDIT PRACTICES OF LISTED CONSTRUCTION COMPANIES IN MALAYSIA: SOME PRELIMINARY EVIDENCE

    OpenAIRE

    Damien LEE; Issham ISMAIL; Daniela MITRAN

    2010-01-01

    This study aims to find out the current internal audit practices of listed construction companies in Malaysia is in compliance with newly released International Professional Practice Framework (IPPF) standards. IPPF standards were recently updated in January 2009 and there are drastic changes from January 2002 version. This event has motivated the study to investigate whether current internal audit practice is in line with newly released standards. More than half of listed construction compan...

  3. LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family.

    Science.gov (United States)

    Guffanti, Guia; Gaudi, Simona; Klengel, Torsten; Fallon, James H; Mangalam, Harry; Madduri, Ravi; Rodriguez, Alex; DeCrescenzo, Paula; Glovienka, Emily; Sobell, Janet; Klengel, Claudia; Pato, Michele; Ressler, Kerry J; Pato, Carlos; Macciardi, Fabio

    2016-06-01

    Recent studies show that human-specific LINE1s (L1HS) play a key role in the development of the central nervous system (CNS) and its disorders, and that their transpositions within the human genome are more common than previously thought. Many polymorphic L1HS, that is, present or absent across individuals, are not annotated in the current release of the genome and are customarily termed "non-reference L1s." We developed an analytical workflow to identify L1 polymorphic insertions with next-generation sequencing (NGS) using data from a family in which SZ segregates. Our workflow exploits two independent algorithms to detect non-reference L1 insertions, performs local de novo alignment of the regions harboring predicted L1 insertions and resolves the L1 subfamily designation from the de novo assembled sequence. We found 110 non-reference L1 polymorphic loci exhibiting Mendelian inheritance, the vast majority of which are already reported in dbRIP and/or euL1db, thus, confirming their status as non-reference L1 polymorphic insertions. Four previously undetected L1 polymorphic loci were confirmed by PCR amplification and direct sequencing of the insert. A large fraction of our non-reference L1s is located within the open reading frame of protein-coding genes that belong to pathways already implicated in the pathogenesis of schizophrenia. The finding of these polymorphic variants among SZ offsprings is intriguing and suggestive of putative pathogenic role. Our data show the utility of NGS to uncover L1 polymorphic insertions, a neglected type of genetic variants with the potential to influence the risk to develop schizophrenia like SNVs and CNVs. © 2016 Wiley Periodicals, Inc. PMID:26990047

  4. Pickles and Ice Cream! Food Cravings in Pregnancy: Hypotheses, Preliminary Evidence, and Directions for Future Research

    Directory of Open Access Journals (Sweden)

    Natalia C. Orloff

    2014-09-01

    Full Text Available Women in the United States experience an increase in food cravings at two specific times during their life, 1 perimenstrually and 2 prenatally. The prevalence of excess gestational weight gain (GWG is a growing concern due to its association with adverse health outcomes in both mothers and children. To the extent that prenatal food cravings may be a determinant of energy intake in pregnancy, a better understanding of craving etiology could be crucial in addressing the issue of excessive GWG. This paper reviews the available literature to corroborate and/or dispute some of the most commonly accepted hypotheses regarding the causes of food cravings during pregnancy, including a role of 1 hormonal changes, 2 nutritional deficits, 3 pharmacologically active ingredients in the desired foods, and 4 cultural and psychosocial factors. An existing model of perimenstrual chocolate craving etiology serves to structure the discussion of these hypotheses. The main hypotheses discussed receive little support, with the notable exception of a postulated role of cultural and psychosocial factors. The presence of cravings during pregnancy is a common phenomenon across different cultures, but the types of foods desired and the adverse impact of cravings on health may be culture-specific. Various psychosocial factors appear to correlate with excess GWG, including the presence of restrained eating. Findings strongly suggest that more research be conducted in this area. We propose that future investigations fall into one of the four following categories: 1 validation of food craving and eating-related measures specifically in pregnant populations, 2 use of ecological momentary assessment to obtain real time data on cravings during pregnancy, 3 implementation of longitudinal studies to address causality between eating disorder symptoms, food cravings, and gestational weight gain, and 4 development of interventions to ensure proper prenatal nutrition and prevent excess GWG.

  5. Laser acupuncture and analgesia: preliminary evidence for a transient and opioid-mediated effect

    Science.gov (United States)

    Whittaker, Peter

    2006-02-01

    Acupuncture is frequently used to treat pain. Although human pain quantification is difficult and often subjective, in rodent models the tail-flick test provides a well-established and objective assessment of analgesia. This test measures the time taken before a rat withdraws its tail from a heat source. Needle and electroacupuncture at the acupuncture point Spleen-6, located at the tibia's posterior margin above the medial malleolus, has been found to increase tail-flick time in rats. The aim of the current study was to determine if laser acupuncture had a similar effect. A 550 μm diameter optic fiber was used to irradiate Spleen-6 for 2 minutes (690 nm, 130 mW) in female Sprague-Dawley rats. In addition, control experiments were performed in which rats were subjected to sham treatment (restraint but no irradiation) or irradiation of an non-acupuncture point (the tail's dorsal surface, 1cm from the base) using the same laser parameters. The baseline tail-flick time was measured and 15 minutes later the laser acupuncture or the control protocols were performed and tail-flick time re-measured 10 minutes after treatment. Additional experiments were done in which the opioid-blocker naloxone (20 mg/kg, intraperitoneal injection) was administered one hour before laser acupuncture. Tailflick time increased after laser acupuncture (P = 0.0002), but returned to baseline values one hour later. In contrast, no increase was found after either sham treatment or tail irradiation. Pretreatment with naloxone attenuated the increase in tail-flick time. In summary, laser acupuncture exerts a transient analgesic effect which may act via an opioid-mediated mechanism.

  6. Precambrian mega lineaments across the Indian sub-continent - Preliminary evidence from offshore magnetic data

    Digital Repository Service at National Institute of Oceanography (India)

    Subrahmanyam, V.; Subrahmanyam, A.S.; Murthy, K.S.R.; Murty, G.P.S.; Sarma, K.V.L.N.S.; SuneetaRani, P.; Anuradha, A.

    in the inversion scheme is that the s eismic intensity is a mea s ure of the peak ground acceleration A , which is a s sociated with the arrival of S - waves r e leased from point source buried in the earth medium, where velocity is co n stant...

  7. Associations between Dopamine and Serotonin Genes and Job Satisfaction: Preliminary Evidence from the Add Health Study

    Science.gov (United States)

    Song, Zhaoli; Li, Wendong; Arvey, Richard D.

    2011-01-01

    Previous behavioral genetic studies have found that job satisfaction is partially heritable. We went a step further to examine particular genetic markers that may be associated with job satisfaction. Using an oversample from the National Adolescent Longitudinal Study (Add Health Study), we found 2 genetic markers, dopamine receptor gene DRD4 VNTR…

  8. Habenula responses to potential and actual loss in major depression: preliminary evidence for lateralized dysfunction.

    Science.gov (United States)

    Furman, Daniella J; Gotlib, Ian H

    2016-05-01

    The habenula has been implicated in predicting negative events and in responding to unexpected negative outcomes. Animal models of depression have supported the hypothesis that perturbations in habenula activity contribute to the pathophysiology of Major Depressive Disorder (MDD), a psychiatric illness characterized by abnormalities in responding to negative feedback and by pessimism in evaluating the likelihood of future events. No research to date, however, has examined human habenula responses to potential and experienced negative outcomes in MDD. In this study, depressed and healthy control participants performed a probabilistic guessing task for monetary rewards and penalties during high-resolution functional magnetic resonance imaging of the habenula. In healthy adults, we observed a pattern of habenula activation consistent with its hypothesized role in predicting future losses and responding to suboptimal outcomes. In contrast, in depressed participants the left habenula was not activated significantly during the prediction or experience of monetary penalty. Complementing this group difference, attenuated habenula activation to negative feedback in control participants was associated with levels of shame and rumination. The results of this study suggest that depressed individuals are characterized by dysfunction in a neural system involved in generating expectations and comparing expectations with objective outcomes. PMID:26884545

  9. Appropriateness of administration of nasogastric medication and preliminary intervention

    Directory of Open Access Journals (Sweden)

    Zhou Q

    2012-11-01

    Full Text Available Ling-Ling Zhu,1 Ling-Cheng Xu,2 Hui-Qin Wang,3 Jing-Fen Jin,3 Hua-Fen Wang,3 Quan Zhou21Cadre Department, 2Department of Pharmacy, 3Division of Nursing, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, ChinaAbstract: A utilization study was performed in a 2200-bed tertiary care teaching hospital. Data mining was performed on all nasogastric medication prescriptions for patients hospitalized in 2011. Nurses were interviewed by questionnaire. A PDCA (Plan-Do-Check-Act cycle was used for continuous quality improvement. The proportion of patients with nasogastric tubes (NGT was 3.2%. A large number of medical orders (n  6261 involved nasogastric medications with a package insert particularly noting that they should not be crushed or opened (group 1 or medications without a specific formulation recommendation in the package insert but having evidence discouraging NGT dosing (group 2. Of the nasogastrically administered sustained-release or controlled-release formulations, a sustained-release sodium valproate tablet formulation was the most prescribed drug and a sustained-release 2.5 mg felodipine tablet was prescribed with the highest proportion of NGT dosing [NGT/(NGT  oral  12.3%]. Among the nasogastrically administered enteric-coated formulations, a myrtol-standardized enteric-coated capsule formulation was the most prescribed drug and a pantoprazole tablet formulation was prescribed with the highest proportion of NGT dosing [NGT/(NGT  oral  19.3%]. Proportions of NGT dosing for amiodarone and carbamazepine (group 2 were 4.8% and 6.3%, respectively. The percentage of nurses with adequate knowledge about pharmaceutical dosage formulations was 60%. The rate of answering correctly as to whether medications in group 1 could be crushed or opened was only 30%. Awareness of evidence discouraging NGT dosing of medications in group 2 was zero. Most nurses (90% left physicians and

  10. Preliminary study of mercury target structure

    Energy Technology Data Exchange (ETDEWEB)

    Kaminaga, Masanori; Haga, Katsuhiro; Hino, Ryutaro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kumasaka, Katsuyuki; Uchida, Shoji; Nakagawa, Toshi; Mori, Seiji; Nishikawa, Akira

    1997-11-01

    Development of a proton accelerator based neutron source (1.5 GeV, 5.3 mA (for neutron source 3.3 mA), thermal power 8 MW) is currently conducted by the Special Task Force for Neutron Science Initiative, JAERI. Preliminary design studies and related R and D of a solid metal target for the first stage (1.5 GeV, 1 mA) and a liquid metal target for both the first and second stages (1.5 GeV, 3.3 mA) are conducted by the Target Group to develop both solid and liquid metal target systems. A few kinds of target structures have been investigated in FY 1996 and the preliminary results for the target structures are described in this paper. Investigation results of alternative materials for the target container are also described in this paper. (author)

  11. A preliminary evaluation of various sealing configurations

    International Nuclear Information System (INIS)

    The overall design approach being established by ONWI for repository seals consists of sections of various materials placed in various seal geometries suitable for performing specific functions in the penetrations. One investigation is directed toward evaluating the sensitivity of the seal component behavior with respect to several seal configurations and material types. Numerical methods are being used to evaluate the influence of the seal system on fluid flow and nuclide migration through the sealed zone. This study was a preliminary investigation of the fluid flow through and around the seal. These preliminary results indicate that the hydraulic conductivity of the interface and disturbed zone appear to control the fluid flow through and around a sealed penetration; and hence, determination of hydraulic conductivities in these zones from laboratory and field investigation should be given a high priority

  12. Fukushima. A preliminary assessment in July 2011

    International Nuclear Information System (INIS)

    Four months after the reactor accidents in Fukushima Daiichi a preliminary assessment of the accident sequence vents is performed based on the available incomplete information. The following topics are discussed: initiating events and accident sequences, radioactive materials release and dispersion, fundamentals on radiation exposure following the accident in the nuclear power plant Fukushima Daiichi, contamination of food stuff, fission product release into the Pacific Ocean, source tern and external radiation exposure in the first year, preliminary radiological assessment, radiological situation throughout the different accident phases (radioactive cloud and fallout, late phase), estimation of radiation exposure in the first year due to decay of short-lived radionuclides based on the state end of July 2011, comparison of the reactor accidents in Chernobyl and Fukushima Daiichi.

  13. Preliminary Analysis of Google+'s Privacy

    OpenAIRE

    Mahmood, Shah; Desmedt, Yvo

    2011-01-01

    In this paper we provide a preliminary analysis of Google+ privacy. We identified that Google+ shares photo metadata with users who can access the photograph and discuss its potential impact on privacy. We also identified that Google+ encourages the provision of other names including maiden name, which may help criminals performing identity theft. We show that Facebook lists are a superset of Google+ circles, both functionally and logically, even though Google+ provides a better user interfac...

  14. Rare earth optogalvanic spectroscopy: preliminary results

    International Nuclear Information System (INIS)

    The IEAv has special interest in the studies of rare earth isotope applications in laser medium and integrated optics as well as aerospace research. We are starting to work with Ytterbium, Erbium, Dysprosium and Neodymium laser selective photoionization research. This paper describes the preliminary results of emission and optogalvanic spectroscopy obtained from a Neodymium hollow cathode lamps. Furthermore these results were used to setup our laser systems to work to leads a Nd isotopes selective laser photoionization. (author)

  15. Preliminary aerothermal design of axial compressors

    OpenAIRE

    Piscopo, Giovanni

    2013-01-01

    This dissertation documents a compressor preliminary design study conducted by the author in fulfilment of his MSc thesis requirements. The compressor is intended for a new development engine within the 20Klbf thrust category, planned to be used on a short-haul aircraft, namely the ERJ-190. A market research suggests that there exists a definite opportunity for a commercially profitable engine within this thrust class. Furthermore, the proposed new engine is projected to out...

  16. PLANT COMMUNITIES OF ALBANIA - A PRELIMINARY OVERVIEW

    Directory of Open Access Journals (Sweden)

    J, RODWELL

    2002-01-01

    Full Text Available The phytosociological analysis of Albania was initiated by F. Markgraf in the 30ies, but still remains incomplete. This is a preliminary list of the plant communities resulting from the literature and from field research carried out during the last years and may represent a first contribution for further research. Many communities are described only by dominant species, other are quoted as nomina nuda. Some further syntaxa. probably present in the study area, are added.

  17. Preliminary plan for treating mixed waste

    Energy Technology Data Exchange (ETDEWEB)

    Vandegrift, G.F.; Conner, C.; Hutter, J.C.; Leonard, R.A.; Nunez, L.; Sedlet, J.; Wygmans, D.G.

    1993-06-01

    A preliminary waste treatment plan was developed for disposing of radioactive inorganic liquid wastes that contain hazardous metals and/or hazardous acid concentrations at Argonne National Laboratory. This plan, which involves neutralization and sulfide precipitation followed by filtration, reduces the concentration of hazardous metals and the acidity so that the filtrate liquid is simply a low-level radioactive waste that can be fed to a low-level waste evaporator.

  18. Monitoring Adverse Drug Reactions: A Preliminary Study

    OpenAIRE

    Reynolds, J. L.

    1981-01-01

    The feasibility of family physicians functioning as monitors of adverse drug reactions (ADR) was examined over one month in ten practices. This was done as a preliminary trial, before attempting to use the 200 family physicians of the National Reporting System of the College of Family Physicians of Canada to monitor ADRs on a national basis. Both of these trials were designed to examine the feasibility of family physicians acting as prospective monitors of ADRs in newly marketed drugs and to ...

  19. Asynchronous Nano-Electronics: Preliminary Investigation

    OpenAIRE

    Martin, Alain J.; Prakash, Piyush

    2008-01-01

    This paper is a preliminary investigation in implementing asynchronous QDI logic in molecular nano-electronics, taking into account the restricted geometry, the lack of control on transistor strengths, the high timing variations. We show that the main building blocks of QDI logic can be successfully implemented; we illustrate the approach with the layout of an adder stage. The proposed techniques to improve the reliability of QDI apply to nano-CMOS as well.

  20. Preliminary safety analysis methodology for the SMART

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Kyoo Hwan; Chung, Y. J.; Kim, H. C.; Sim, S. K.; Lee, W. J.; Chung, B. D.; Song, J. H. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    This technical report was prepared for a preliminary safety analysis methodology of the 330MWt SMART (System-integrated Modular Advanced ReacTor) which has been developed by Korea Atomic Energy Research Institute (KAERI) and funded by the Ministry of Science and Technology (MOST) since July 1996. This preliminary safety analysis methodology has been used to identify an envelope for the safety of the SMART conceptual design. As the SMART design evolves, further validated final safety analysis methodology will be developed. Current licensing safety analysis methodology of the Westinghouse and KSNPP PWRs operating and under development in Korea as well as the Russian licensing safety analysis methodology for the integral reactors have been reviewed and compared to develop the preliminary SMART safety analysis methodology. SMART design characteristics and safety systems have been reviewed against licensing practices of the PWRs operating or KNGR (Korean Next Generation Reactor) under construction in Korea. Detailed safety analysis methodology has been developed for the potential SMART limiting events of main steam line break, main feedwater pipe break, loss of reactor coolant flow, CEA withdrawal, primary to secondary pipe break and the small break loss of coolant accident. SMART preliminary safety analysis methodology will be further developed and validated in parallel with the safety analysis codes as the SMART design further evolves. Validated safety analysis methodology will be submitted to MOST as a Topical Report for a review of the SMART licensing safety analysis methodology. Thus, it is recommended for the nuclear regulatory authority to establish regulatory guides and criteria for the integral reactor. 22 refs., 18 figs., 16 tabs. (Author)

  1. Nationwide Census of Institutional Repositories: Preliminary Findings

    OpenAIRE

    Markey, Karen; St. Jean, Beth; Rieh, Soo Young; Yakel, Elizabeth; Kim, Jihyun; Kim, Yong-Mi

    2007-01-01

    The MIRACLE (Making Institutional Repositories A Collaborative Learning Environment) Project is a multi-phased research project that is investigating the development of institutional repositories (IRs) in U. S. colleges and universities to identify models and best practices in the administration, technical infrastructure, access to, and preservation of repository collections. This paper features preliminary findings from the project’s first phase, a nationwide census that will reveal the exte...

  2. Preliminary Assessment of Remote Wind Sites

    OpenAIRE

    Bilal, Muhammad; Araya, Guillermo; Birkelund, Yngve

    2015-01-01

    Wind energy is becoming a reliable and affordable source of clean energy and is rapidly expanding to remote places around the world. A crucial input for wind farming prospect is the assessment of potential wind sites. Sites, especially remotely located, often do not have a wind resource map and thus lack credible historical records of wind resources. Measurement campaigns to map these sites are costly and time consuming. In this paper, a method for preliminary wind resource assess...

  3. Preliminary plan for treating mixed waste

    International Nuclear Information System (INIS)

    A preliminary waste treatment plan was developed for disposing of radioactive inorganic liquid wastes that contain hazardous metals and/or hazardous acid concentrations at Argonne National Laboratory. This plan, which involves neutralization and sulfide precipitation followed by filtration, reduces the concentration of hazardous metals and the acidity so that the filtrate liquid is simply a low-level radioactive waste that can be fed to a low-level waste evaporator

  4. Preliminary isotope studies in Poyang Lake

    International Nuclear Information System (INIS)

    Poyang Lake is the largest fresh water lake in China, and the largest wetland protection area in Asia. The lake serves as the largest buffer for the Yangtze River as well. In order to make better understanding of the water dynamics, water balance, water chemistry, and the relations between lake, rivers and groundwater, isotope investigation has been carried out systematically for one and a half hydrological years. The paper reports the preliminary results of the study. (author)

  5. Preliminary isotope studies of Poyang Lake, China

    International Nuclear Information System (INIS)

    Poyang Lake is the largest fresh water lake in China, and the largest wetland protection area in Asia. The lake serves as the largest buffer for the Yangtze River as well. In order to make better understanding of the water dynamics, water balance, water chemistry, and the relations between lake, rivers and groundwater, isotope investigation has been carried out systematically for one and a half hydrological years. The paper will report the preliminary results from this program. (author)

  6. Preliminary rock mechanics laboratory: Investigation plan

    International Nuclear Information System (INIS)

    This document presents the rationale for rock mechanics laboratory testing (including the supporting analysis and numerical modeling) planned for the site characterization of a nuclear waste repository in salt. This plan first identifies what information is required for regulatory and design purposes, and then presents the rationale for the testing that satisfies the required information needs. A preliminary estimate of the minimum sampling requirements for rock laboratory testing during site characterization is also presented. Periodic revision of this document is planned

  7. Preliminary Specification of Services and Protocols

    OpenAIRE

    Nuno Neves; Paulo Verissimo

    2008-01-01

    This document describes the preliminary specification of services and protocols for the Crutial Architecture. The Crutial Architecture definition, first addressed in Crutial Project Technical Report D4 (January 2007), intends to reply to a grand challenge of computer science and control engineering: how to achieve resilience of critical information infrastructures, in particular in the electrical sector. The definitions herein elaborate on the major architectural options and components establ...

  8. CRUTIAL - Preliminary specification of services and protocols

    OpenAIRE

    Neves, Nuno; Verissimo, Paulo; Bondavalli, Andrea; Grandoni, Fabrizio; et al, .

    2008-01-01

    This document describes the preliminary specification of services and protocols for the Crutial Architecture. The Crutial Architecture definition, first addressed in Crutial Project Technical Report D4 (January 2007), intends to reply to a grand challenge of computer science and control engineering: how to achieve resilience of critical information infrastructures, in particular in the electrical sector. The definitions herein elaborate on the major architectural options and components establ...

  9. Report on Preliminary NHA 2005 in Kosovo

    OpenAIRE

    Jedomskihh-Eigo, Natalja

    2007-01-01

    This is a report which includes preliminary data from the year 2005 and description of potential data sources for National Health Account (NHA) in Kosovo. This year was chosen because it was the only year where data on health expenditures from all existing data sources was available. Natalja Jedomskihh-Eigo (consultant) prepared the report after her visit to Kosovo, 15 - 21 April, 2007. Th...

  10. Bunch compression for the TLC: Preliminary design

    International Nuclear Information System (INIS)

    A preliminary design of a TLC bunch compressor as a two-stage device is described. The main parameters of the compressor, as well as results of some simulations, are presented. They show that the ideal system (no imperfections) does the job of transmitting transverse emittances without distortions (at least up to the second-order terms) producing at the same time the desired bunch length of 50 μm. 9 refs., 6 figs., 4 tabs

  11. Exploratory shaft facility preliminary designs - Paradox Basin. Technical report

    International Nuclear Information System (INIS)

    The purpose of the Preliminary Design Report, Paradox Basin, is to provide a description of the preliminary design for an Exploratory Shaft Facility in the Paradox Basin, Utah. This issue of the report describes the preliminary design for constructing the exploratory shaft using the Large Hole Drilling Method of construction and outlines the preliminary design and estimates of probable construction cost. The Preliminary Design Report is prepared to complement and summarize other documents that comprise the design at the preliminary stage of completion, December 1982. Other design documents include drawings, cost estimates and schedules. The preliminary design drawing package, which includes the construction schedule drawing, depicts the descriptions in this report. For reference, a list of the drawing titles and corresponding numbers is included in the Appendix. The report is divided into three principal sections: Design Basis, Facility Description, and Construction Cost Estimate. 30 references

  12. Preliminary Efficacy of a Behavioral Parent Training Program for Children With ADHD in Pakistan.

    Science.gov (United States)

    Malik, Tamkeen Ashraf; Rooney, Mary; Chronis-Tuscano, Andrea; Tariq, Naeem

    2014-03-12

    Objective: In an effort to address the lack of evidence-based interventions for ADHD in developing South Asian countries, we examined the preliminary efficacy of a behavioral parent training program in Pakistan. Method: A quasi-experimental design was utilized. Eighty-five 4- to 12-year-old children with clinically significant ADHD symptoms participated: 55 were recruited from hospital clinics (active treatment group) and 30 were recruited from schools (waitlist control group). Parent and teacher ratings of ADHD, oppositional defiant disorder (ODD), and conduct disorder (CD) symptoms and impairment were collected. Results: Using intent-to-treat analyses, the treatment group showed significant pre-post improvement on parent-reported ODD symptoms and ADHD-related impairment. Teacher ratings showed no improvement. Conclusion: This study provides preliminary evidence for the feasibility and effectiveness of behavioral parenting training for children with ADHD in Pakistan and represents a critical first step in identifying evidence-based treatments for Pakistani children with ADHD. PMID:24621459

  13. A generalized evidence distance

    Institute of Scientific and Technical Information of China (English)

    Hongming Mo; Xi Lu; Yong Deng

    2016-01-01

    How to efficiently measure the distance between two basic probability assignments (BPAs) is an open issue. In this paper, a new method to measure the distance between two BPAs is proposed, based on two existing measures of evidence distance. The new proposed method is comprehen-sive and generalized. Numerical examples are used to ilus-trate the effectiveness of the proposed method.

  14. Evidence of Absence software

    Science.gov (United States)

    Dalthorp, Daniel; Huso, Manuela M. P.; Dail, David; Kenyon, Jessica

    2014-01-01

    Evidence of Absence software (EoA) is a user-friendly application used for estimating bird and bat fatalities at wind farms and designing search protocols. The software is particularly useful in addressing whether the number of fatalities has exceeded a given threshold and what search parameters are needed to give assurance that thresholds were not exceeded. The software is applicable even when zero carcasses have been found in searches. Depending on the effectiveness of the searches, such an absence of evidence of mortality may or may not be strong evidence that few fatalities occurred. Under a search protocol in which carcasses are detected with nearly 100 percent certainty, finding zero carcasses would be convincing evidence that overall mortality rate was near zero. By contrast, with a less effective search protocol with low probability of detecting a carcass, finding zero carcasses does not rule out the possibility that large numbers of animals were killed but not detected in the searches. EoA uses information about the search process and scavenging rates to estimate detection probabilities to determine a maximum credible number of fatalities, even when zero or few carcasses are observed.

  15. What Counts as Evidence?

    Science.gov (United States)

    Dougherty Stahl, Katherine A.

    2014-01-01

    Each disciplinary community has its own criteria for determining what counts as evidence of knowledge in their academic field. The criteria influence the ways that a community's knowledge is created, communicated, and evaluated. Situating reading, writing, and language instruction within the content areas enables teachers to explicitly…

  16. Evidence-based policy

    DEFF Research Database (Denmark)

    Vohnsen, Nina Holm

    2013-01-01

    research community (e.g. Boden & Epstein 2006; House of Commons 2006; Cartwright et al 2009; Rod 2010; Vohnsen 2011). This article intends to draw out some general pitfalls in the curious meeting of science and politics by focusing on a particular attempt to make evidence-based legislation in Denmark (for...

  17. The Appraising Evidence Game.

    Science.gov (United States)

    Mick, JoAnn

    2016-04-01

    This column shares the best evidence-based strategies and innovative ideas on how to facilitate the learning of EBP principles and processes by clinicians as well as nursing and interprofessional students. Guidelines for submission are available at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1741-6787. PMID:26766171

  18. Building Bridges to the Economic Mainstream for African American Male Ex-Offenders: A Preliminary Assessment of an Inmate Education Re-Entry Program.

    Science.gov (United States)

    Johnson, James H., Jr.; Farrell, Walter C., Jr.; Braithwaite, Lawrence P.

    This paper describes a state-funded inmate education and re-entry program that provides soft skills training for soon-to-be released offenders. The paper presents preliminary evidence regarding the impact of this training on 14 young male participants. Data came from information prepared by inmates throughout the training program and ethnographic…

  19. Development and preliminary evaluation of a rehabilitation consult for survivors of head and neck cancer: an intervention mapping protocol

    OpenAIRE

    McEwen, Sara E; Aileen M. Davis; Jones, Jennifer M; Martino, Rosemary; Poon, Ian; Rodriguez, Ana Maria; Ringash, Jolie

    2015-01-01

    Background Evidence suggests that rehabilitation interventions can improve function and quality of life in survivors of head and neck cancer (HNC), but there is a lack of coordinated, integrated services, and those offered are inconsistent. To address these gaps, we will develop and conduct preliminary evaluation of a rehabilitation consult, built on the theoretical foundations of goal setting and self-management, and composed of a brief functional evaluation, a resource compendium, and colla...

  20. Why Isaac Newton Rejected Astrology: A Preliminary Reconstruction or "Newton's Comets and the Transformation of Astrology": 20 Years Later

    OpenAIRE

    Rutkin, H. Darrel

    2006-01-01

    [EN] What was Isaac Newton's relationship to astrology? Unlike with bis study and practice of alchemy, there is very little evidence on which to base a well-established answer. In this preliminary investigation, I argue that Newton rejected astrology for both personal and ideological reasons. This anti-astrological valence is primarily revealed in manuscript writings related to bis mid-1680s theological tract, "The Philosophical Origins of Gentile Theology." In addition to arguing for this an...

  1. Another step closer to measuring the ghosts in the nursery: preliminary validation of the Trauma Reflective Functioning Scale

    OpenAIRE

    Ensink, Karin; Berthelot, Nicolas; Bernazzani, Odette; Normandin, Lina; Fonagy, Peter

    2014-01-01

    The aim of this study was to examine preliminary evidence of the validity of the Trauma Reflective Functioning Scale and to investigate reflective functioning (RF) and attachment in pregnant women with histories of trauma, with a particular focus on the capacity to mentalize regarding trauma and its implications for adaptation to pregnancy and couple functioning. The Adult Attachment Interview was used to assess attachment, unresolved trauma and mentalization (measured as RF) regarding relati...

  2. Balkan (endemic) nephropathy and foodborn ochratoxin A: preliminary results of a survey of foodstuffs.

    Science.gov (United States)

    Krogh, P; Hald, B; Plestina, R; Ceović, S

    1977-06-01

    Ochratoxin A is a nephrotoxic fungal metabolite (mycotoxin) occurring in foodstuffs. The compound is causally associated with mycotoxic porcine nephropathy, a disease comparable with a human kidney disease, Balkan endemic nephropathy. A preliminary survey of home-produced foodstuffs in areas of Yugoslavia revealed that contamination with ochratoxin A is more frequent in an area where Balkan endemic nephropathy is prevalent (endemic area) than in area where this disease is absent. This indicates higher exposure to foodborn ochratoxin A in the endemic area. Thus further evidence is provided supporting the hypothesis that ochratoxin A is a disease determinant of Balkan endemic nephropathyk0 PMID:888703

  3. Hypoallergenic properties of donkey's milk: a preliminary study

    Directory of Open Access Journals (Sweden)

    Silvia Vincenzetti

    2014-06-01

    Full Text Available Cow's milk protein allergy (CMPA is an abnormal immunological response to cow milk proteins, which results in IgE-mediated reactions. The therapeutic strategy to respond to CMPA envisages the total elimination of milk or the administration of cow's milk substitutes. For this reason the use of milk from other mammalian species was tested. Among them, donkey's milk proved to be the best alternative in feeding infants affected by CMPA, since its chemical composition is comparable to human milk. In this work an in vitro study was performed in order to analyze the IgE reactivity to milk protein allergens from cow, donkey and goat. In particular, immunoblotting experiments using sera from milk-allergic and non-allergic adult volunteers were conducted with the aim of verifying the hypoallergenic property of donkey's milk. This study provided a preliminary evidence of the hypoallergenicity of donkey's milk when compared to bovine and goat milk. Considering the obtained results, it would be possible to develop a sensitive diagnostic method for CMPA detection, based on chromatographic and immunoblotting analysis.

  4. Preliminary report: The Little Skull Mountain earthquake, June 29, 1992

    International Nuclear Information System (INIS)

    The Little Skull Mountain earthquake occurred about 20 km from the potential high level nuclear repository at Yucca Mountain. The magnitude was 5.6, and the focal mechanism indicates normal faulting on a northeast trending structure. There is evidence that the earthquake was triggered by the magnitude MS = 7.5 earthquake in Landers, California, which occurred less than 24 hours earlier. Preliminary locations of the hypocenter and several aftershocks define an L shaped pattern near the southern boundary of the Nevada Test Site. One arm trends to the northeast beneath Little Skull Mountain, and a shorter, more diffuse zone trends to the southeast. The aftershocks are mostly located at depths between 7 km and 11 km, and may suggest a southeast dipping plane. There is no clear correlation with previously mapped surface faulting. The strongest recorded acceleration is about 0.21 g at Lathrop Wells, Nevada, 15 km from the epicenter. An extensive network of aftershock recorders was installed by the Seismological Laboratory, University of Nevada, Reno, by the US Geological Survey, Golden, Colorado, and by Lawrence Livermore Laboratory, Livermore, California. Aftershock experiments are ongoing as of November, 1992, and include experiments to improve location, depth, focal mechanism, and stress drop, study basin and ridge response near the epicenter and at Midway Valley, and study response of a tunnel at Little Skull Mountain. Analysis of this data, which includes thousands of aftershocks, has only begun

  5. Preliminary investigations on the antibacterial activity of zinc oxide nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Ramani, Meghana; Ponnusamy, S., E-mail: suruponnus@gmail.com; Muthamizhchelvan, C. [Center for Materials Science and Nano Devices, SRM University, Department of Physics (India)

    2013-04-15

    In this study, we present a systematic investigation on the evolution of nanorods of diameter 35-40 nm and 1-2 {mu}m length from nanoparticles of diameter 30-35 nm by varying the concentration of 2,6-lutidine which acts as a shape-directing agent in the synthesis process. This variation in morphology was studied using transmission electron microscopy. The surface capping agent was subsequently removed by heating during the synthesis process and confirmed using Fourier Transform Infra-red spectroscopy. Sufficient quantity of surface defects in the form of oxygen vacancies was observed from the photoluminescence analysis of the synthesized nanostructures. The concentration of defects decreased as the shape transits from nanoparticles to nanorods. The synthesized samples were preliminarily studied for their antibacterial activity against four model (gram-positive and gram-negative) pathogens by disk diffusion method and growth curve analysis. The calculated generation time indicates higher activity for nanoparticles than nanorods. However, the difference in the activity against different pathogens and their dependence on the concentration of defects indicate oxidative stress in addition to mechanical membrane damage as the major toxicity mechanism. Overall, the experimental findings are preliminary evidence supporting the possibility of developing zinc oxide nanostructures as antibacterial agents against a wide range of microorganisms to control and prevent the spreading of bacterial infections.

  6. NCCN Evidence Blocks.

    Science.gov (United States)

    Carlson, Robert W; Jonasch, Eric

    2016-05-01

    NCCN has developed a series of Evidence Blocks: graphics that provide ratings for each recommended treatment regimen in terms of efficacy, toxicity, quality and consistency of the supporting data, and affordability. The NCCN Evidence Blocks are currently available in 10 tumor types within the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines). At a glance, patients and providers can understand how a given treatment was assessed by the NCCN Guidelines Panel and get a sense of how a given treatment may match individual needs and preferences. Robert W. Carlson, MD, CEO of NCCN, described the reasoning behind this new feature and how the tool is used, and Eric Jonasch, MD, Professor of Genitourinary Medical Oncology at The University of Texas MD Anderson Cancer Center, and Vice Chair of the NCCN Kidney Cancer Panel, described its applicability in the management of metastatic renal cell carcinoma. PMID:27226499

  7. Inflation, evidence and falsifiability

    CERN Document Server

    Gubitosi, Giulia; Magueijo, Joao; Allison, Rupert

    2015-01-01

    In this paper we consider the issue of paradigm evaluation by applying Bayes' theorem along the following nested chain of progressively more complex structures: i) parameter estimation (within a model), ii) model selection and comparison (within a paradigm), iii) paradigm evaluation. In such a chain the Bayesian evidence works both as the posterior's normalization at a given level and as the likelihood function at the next level up. Whilst raising no objections to the standard application of the procedure at the two lowest levels, we argue that it should receive an essential modification when evaluating paradigms, in view of the issue of falsifiability. By considering toy models we illustrate how unfalsifiable models and paradigms are always favoured by the Bayes factor. We argue that the evidence for a paradigm should not only be high for a given dataset, but exceptional with respect to what it would have been, had the data been different. We propose a measure of falsifiability (which we term predictivity), ...

  8. The Evidence on Globalization

    OpenAIRE

    Potrafke, Niklas

    2014-01-01

    Globalization is blamed for many socio-economic shortcomings. I discuss the consequences of globalization by surveying the empirical globalization literature. My focus is on the KOF indices of globalization (Dreher 2006a and Dreher et al. 2008a), that have been used in more than 100 studies. Early studies using the KOF index reported correlations between globalization and several outcome variables. Studies published more recently identify causal effects. The evidence shows that globalization ...

  9. Preliminary risk assessments of the small HTGR

    International Nuclear Information System (INIS)

    Preliminary investment and safety risk assessments were performed for a preconceptual design of a four-module 250-MW(t) side-by-side steel-vessel pebble bed HTGR plant. Broad event spectra were analyzed involving (1) component damage resulting in unscheduled plant outages and (2) fission product releases resulting in offsite doses. The preliminary assessment indicates at this stage of the design that two categories of events govern the investment risk envelope: 1. Primary coolant leaks which release some circulating and plateout activity that contaminates the confinement. 2. Turbogenerator damage which involves extensive turbine blade failure. Primary coolant leaks are important contributors because associated cleanup and decontamination requirements result in longer outages that arise from other events with comparable frequencies. Turbogenerator damage is the salient low-frequency investment risk accident due to the relatively long outages being experienced in the industry. Thermal transients are unimportant investment risk contributors because pressurized core heatups cause little damage, and depressurized core heatups occur at negligible frequencies relative to the forced outage goal. Two accident families have been examined for safety risk: 1. Primary coolant leaks which release some circulating and plateout activity to the confinement. 2. Releases initiated by steam generator leaks which can release radioactivity directly to the environment. Primary coolant leaks dominate the upper portion of the safety risk envelope, while releases initiated by steam generator leaks govern the lower frequency region. These preliminary results demonstrate investment and safety risk goal compliance at this stage in the design process. Studies are continuing in order to provide valuable insights into risk-significant events to assure a balanced approach to meeting user and regulatory requirements. (author)

  10. Preliminary design of twin-cylinder engines

    OpenAIRE

    Louvigny, Yannick

    2008-01-01

    This report deals with the preliminary design of a twin-cylinder engine. The goal of the work is not to make the detailed design of the engine but to draw the main characteristics of each kind of engine and to investigate which configuration of twin-cylinder engine matches in the best way to given requirements. A simple model is developed from the motion equations of the rotating and oscillating parts of piston engine. This model allows calculating the values of the inertia forces and mom...

  11. PRELIMINARY PROGRAMMED WHOLE—BODY COUNTER

    Institute of Scientific and Technical Information of China (English)

    张少东; 郑文忠; 等

    1995-01-01

    It is capable of giving the initial intakes of radionuclides and the assessment quantitites used in radiation protection according to its measured results of radionuclides in vivo.It is accomplished by providing the software of controlling,interface and internal dose estimation programs to the original iron cabin shielding whole-body counter.The preliminary application shows that its data processing is rapid and correct,and can meet the requirement of rapid internal radioactive contamination monitoring and diagnosing in case of lots of internal contamination subjects happened in nuclear accident.

  12. Bereitschaftspotential in tic disorders : a preliminary observation.

    Directory of Open Access Journals (Sweden)

    Duggal H

    2002-10-01

    Full Text Available Sensory phenomena in tic disorders such as Tourette′s syndrome are known but are substantiated by only a handful of studies. In this preliminary report, we studied premonitory urge, a type of sensory phenomenon in three patients of tic disorders. Bereitschaftspotential, a movement-related cognitive potential indicative of motor preparation, was assessed in these patients. As bereitschaftspotential was observed in all our cases prior to occurrence of tics, it is speculated that tics are not entirely involuntary but are quasi-volitional in nature. Bereitschaftspotential may thus represent a neurophysiological marker of premonitory urge in tic disorders. Implications of exploring the voluntary nature of tics are discussed.

  13. Preliminaries of probabilistic hierarchical fault detection

    Czech Academy of Sciences Publication Activity Database

    Jirsa, Ladislav; Pavelková, Lenka; Dedecius, Kamil

    Prague: Institute of Information Theory and Automation, 2013 - (Guy, T.; Kárný, M.) ISBN 978-80-903834-8-7. [The 3rd International Workshop on Scalable Decision Making: Uncertainty, Imperfection, Deliberation held in conjunction with ECML/PKDD 2013. Prague (CZ), 23.09.2013-23.09.2013] R&D Projects: GA MŠk 7D12004; GA ČR GA13-13502S Institutional support: RVO:67985556 Keywords : Fault detection * FDI * probabilistic logic * system health Subject RIV: BC - Control Systems Theory http://library.utia.cas.cz/separaty/2013/AS/jirsa-preliminaries of probabilistic hierarchical fault detection.pdf

  14. Evaluation of PROPELLER MR imaging. Preliminary experiences

    Energy Technology Data Exchange (ETDEWEB)

    Mori, Harushi; Aoki, Shigeki; Abe, Osamu [Tokyo Univ. (Japan). Hospital] [and others

    2002-05-01

    Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction (PROPELLER) MR imaging (MRI) has a unique ability to correct motion artifacts and is expected to be useful in diffusion-weighted MRI. This article describes preliminary experiences with PROPELLER MRI. PROPELLER uses a radial scan variation of the fast spin-echo sequence and it shows much less spatial deterioration than the echo-planar imaging sequence. To determine the optimal parameters of this technique, we calculated the signal intensities of phantoms and brains in various settings. PROPELLER MR examinations were also performed in 66 patients for clinical use. PROPELLER MRI appears to be a promising and useful technique. (author)

  15. Preliminary simulation study of doppler reflectometry

    International Nuclear Information System (INIS)

    A preliminary simulation study of Doppler reflectometry is performed. The simulations solve Maxwell's equations by a finite difference time domain (FDTD) code method in two dimensions. A moving corrugated metal target is used as a plasma cutoff layer to study the basic features of Doppler reflectometry. We examined the effects of the full width at half maximum (FWHM) of the electromagnetic waves and the corrugation depth of the metal target. Furthermore, the effect of a nonuniform plasma is studied using this FDTD analysis. The Doppler shift and velocity are compared with those obtained from FDTD analysis of a uniform plasma. (author)

  16. Preliminary Survey for Indirect Energy Consumption Control

    Science.gov (United States)

    Inoue, Shuki; Mimura, Eiji; Aoki, Shingo; Tsuji, Hiroshi

    To save home energy consumption, this paper proposes an indirect load control based on transaction data. The indirect load control consists of (1) stores a lot of transaction data with consumers’ attribute and their life style, (2) shows the positional data in the same category consumers for diagnosis, (3) notifies a consumer his status, (4) expect him to control their energy consumption indirectly. The paper shows the possibility for box chart in showing positional data and for information entropy calculation in generating consumer’s categories as preliminary survey.

  17. Insufficient Evidence: The Problems of Evidence-Based Nursing.

    Science.gov (United States)

    Rolfe, Gary

    1999-01-01

    Challenges the wisdom of basing nursing practice on the findings of statistical research and offers objections to the philosophy of evidence-based nursing. Proposes rethinking what counts as evidence, suggesting a model based on reflection after the event. (SK)

  18. Evidence and Ethics (Editorial)

    OpenAIRE

    Alison Brettle

    2012-01-01

    Welcome to the December issue of EBLIP, the final issue of my first year as Editor-in-Chief. A year which I have thoroughly enjoyed and one where the fears over what to write in my editorials haven’t materialised. This quarter, ethics has featured quite heavily in my working life so I decided to make this the topic of the editorial, sharing some of my thoughts regarding evidence, ethics and how ethical principles are implemented within the EBLIP journal.Ethics are “principles of conduct or st...

  19. Evidence for mantle plumes?

    Science.gov (United States)

    Anderson, Don L; Natland, James H

    2007-11-22

    Geophysical hotspots have been attributed to partially molten asthenosphere, fertile blobs, small-scale convection and upwellings driven by core heat. Most are short-lived or too close together to be deeply seated, and do not have anomalous heat flow or temperature; many are related to tectonic features. Bourdon et al. investigate the dynamics of mantle plumes from uranium-series geochemistry and interpret their results as evidence for thermal plumes. Here we show why alternative mechanisms of upwelling and melting should be considered. PMID:18033248

  20. Preliminary results of ground-motion characteristics

    Directory of Open Access Journals (Sweden)

    Francesca Bozzoni

    2012-10-01

    Full Text Available The preliminary results are presented herein for the engineering applications of the characteristics of the ground motion induced by the May 20, 2012, Emilia earthquake. Shake maps are computed to provide estimates of the spatial distribution of the induced ground motion. The signals recorded at the Mirandola (MRN station, the closest to the epicenter, have been processed to obtain acceleration, velocity and displacement response spectra. Ground-motion parameters from the MRN recordings are compared with the corresponding estimates from recent ground-motion prediction equations, and with the spectra prescribed by the current Italian Building Code for different return periods. The records from the MRN station are used to plot the particle orbit (hodogram described by the waveform. The availability of results from geotechnical field tests that were performed at a few sites in the Municipality of Mirandola prior to this earthquake of May 2012 has allowed preliminary assessment of the ground response. The amplification effects at Mirandola are estimated using fully stochastic site-response analyses. The seismic input comprises seven actual records that are compatible with the Italian code-based spectrum that refers to a 475-year return period. The computed acceleration response spectrum and the associated dispersion are compared to the spectra calculated from the recordings of the MRN station. Good agreement is obtained for periods up to 1 s, especially for the peak ground acceleration. For the other periods, the spectral acceleration of the MRN recordings exceeds that of the computed spectra.

  1. Preliminary remediation goals for ecological endpoints

    International Nuclear Information System (INIS)

    Preliminary remediation goals (PRGs) are useful for risk assessment and decision making at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites. PRGs are upper concentration limits for specific chemicals in specific environmental media that are anticipated to protect human health or the environment. They can be used for multiple remedial investigations at multiple facilities. In addition to media and chemicals of potential concern, the development of PRGs generally requires some knowledge or anticipation of future land use. In Preliminary Remediation Goals for Use at the U.S. Department of Energy Oak Ridge Operations Office (Energy Systems 1995), PRGs intended to protect human health were developed with guidance from Risk Assessment Guidance for Superfund: Volume I - Human Health Evaluation Manual, Part B (RAGS) (EPA 1991). However, no guidance was given for PRGs based on ecological risk. The numbers that appear in this volume have, for the most part, been extracted from toxicological benchmarks documents for Oak Ridge National Laboratory (ORNL) and have previously been developed by ORNL. The sources of the quantities, and many of the uncertainties associated with their derivation, are described in this technical memorandum

  2. Ship design methodologies of preliminary design

    CERN Document Server

    Papanikolaou, Apostolos

    2014-01-01

    This book deals with ship design and in particular with methodologies of the preliminary design of ships. The book is complemented by a basic bibliography and five appendices with useful updated charts for the selection of the main dimensions and other basic characteristics of different types of ships (Appendix A), the determination of hull form  from the data of systematic hull form series (Appendix B), the detailed description of the relational method for the preliminary estimation of ship weights (Appendix C), a brief review of the historical evolution of shipbuilding science and technology from the prehistoric era to date (Appendix D) and finally a historical review of regulatory developments of ship's damage stability to date (Appendix E).  The book can be used as textbook for ship design courses or as additional reading for university or college students of naval architecture courses and related disciplines; it may also serve as a reference book for naval architects, practicing engineers of rel...

  3. Preliminary Hazards Analysis Plasma Hearth Process

    Energy Technology Data Exchange (ETDEWEB)

    Aycock, M.; Coordes, D.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

    1993-11-01

    This Preliminary Hazards Analysis (PHA) for the Plasma Hearth Process (PHP) follows the requirements of United States Department of Energy (DOE) Order 5480.23 (DOE, 1992a), DOE Order 5480.21 (DOE, 1991d), DOE Order 5480.22 (DOE, 1992c), DOE Order 5481.1B (DOE, 1986), and the guidance provided in DOE Standards DOE-STD-1027-92 (DOE, 1992b). Consideration is given to ft proposed regulations published as 10 CFR 830 (DOE, 1993) and DOE Safety Guide SG 830.110 (DOE, 1992b). The purpose of performing a PRA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PRA then is followed by a Preliminary Safety Analysis Report (PSAR) performed during Title I and II design. This PSAR then leads to performance of the Final Safety Analysis Report performed during construction, testing, and acceptance and completed before routine operation. Radiological assessments indicate that a PHP facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous material assessments indicate that a PHP facility will be a Low Hazard facility having no significant impacts either onsite or offsite to personnel and the environment.

  4. Preliminary Hazards Analysis Plasma Hearth Process

    International Nuclear Information System (INIS)

    This Preliminary Hazards Analysis (PHA) for the Plasma Hearth Process (PHP) follows the requirements of United States Department of Energy (DOE) Order 5480.23 (DOE, 1992a), DOE Order 5480.21 (DOE, 1991d), DOE Order 5480.22 (DOE, 1992c), DOE Order 5481.1B (DOE, 1986), and the guidance provided in DOE Standards DOE-STD-1027-92 (DOE, 1992b). Consideration is given to ft proposed regulations published as 10 CFR 830 (DOE, 1993) and DOE Safety Guide SG 830.110 (DOE, 1992b). The purpose of performing a PRA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PRA then is followed by a Preliminary Safety Analysis Report (PSAR) performed during Title I and II design. This PSAR then leads to performance of the Final Safety Analysis Report performed during construction, testing, and acceptance and completed before routine operation. Radiological assessments indicate that a PHP facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous material assessments indicate that a PHP facility will be a Low Hazard facility having no significant impacts either onsite or offsite to personnel and the environment

  5. Business System Planning Project, Preliminary System Design

    International Nuclear Information System (INIS)

    CH2M HILL Hanford Group, Inc. (CHG) is currently performing many core business functions including, but not limited to, work control, planning, scheduling, cost estimating, procurement, training, and human resources. Other core business functions are managed by or dependent on Project Hanford Management Contractors including, but not limited to, payroll, benefits and pension administration, inventory control, accounts payable, and records management. In addition, CHG has business relationships with its parent company CH2M HILL, U.S. Department of Energy, Office of River Protection and other River Protection Project contractors, government agencies, and vendors. The Business Systems Planning (BSP) Project, under the sponsorship of the CH2M HILL Hanford Group, Inc. Chief Information Officer (CIO), have recommended information system solutions that will support CHG business areas. The Preliminary System Design was developed using the recommendations from the Alternatives Analysis, RPP-6499, Rev 0 and will become the design base for any follow-on implementation projects. The Preliminary System Design will present a high-level system design, providing a high-level overview of the Commercial-Off-The-Shelf (COTS) modules and identify internal and external relationships. This document will not define data structures, user interface components (screens, reports, menus, etc.), business rules or processes. These in-depth activities will be accomplished at implementation planning time

  6. Preliminary design for a maglev development facility

    Energy Technology Data Exchange (ETDEWEB)

    Coffey, H.T.; He, J.L.; Chang, S.L.; Bouillard, J.X.; Chen, S.S.; Cai, Y.; Hoppie, L.O.; Lottes, S.A.; Rote, D.M. [Argonne National Lab., IL (United States); Zhang, Z.Y. [Polytechnic Univ., Brooklyn, NY (United States); Myers, G.; Cvercko, A. [Sterling Engineering, Westchester, IL (United States); Williams, J.R. [Alfred Benesch and Co., Chicago, IL (United States)

    1992-04-01

    A preliminary design was made of a national user facility for evaluating magnetic-levitation (maglev) technologies in sizes intermediate between laboratory experiments and full-scale systems. A technical advisory committee was established and a conference was held to obtain advice on the potential requirements of operational systems and how the facility might best be configured to test these requirements. The effort included studies of multiple concepts for levitating, guiding, and propelling maglev vehicles, as well as the controls, communications, and data-acquisition and -reduction equipment that would be required in operating the facility. Preliminary designs for versatile, dual 2-MVA power supplies capable of powering attractive or repulsive systems were developed. Facility site requirements were identified. Test vehicles would be about 7.4 m (25 ft) long, would weigh form 3 to 7 metric tons, and would operate at speeds up to 67 m/s (150 mph) on a 3.3-km (2.05-mi) elevated guideway. The facility would utilize modular vehicles and guideways, permitting the substitution of levitation, propulsion, and guideway components of different designs and materials for evaluation. The vehicle would provide a test cell in which individual suspension or propulsion components or subsystems could be tested under realistic conditions. The system would allow economical evaluation of integrated systems under varying weather conditions and in realistic geometries.

  7. A preliminary neutron crystallographic study of thaumatin

    Energy Technology Data Exchange (ETDEWEB)

    Teixeira, Susana C. M. [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); Blakeley, Matthew P. [Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); Leal, Ricardo M. F. [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); ESRF, 6 Rue Jules Horowitz, BP-220, 38043 Grenoble (France); Mitchell, Edward P. [EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); ESRF, 6 Rue Jules Horowitz, BP-220, 38043 Grenoble (France); Forsyth, V. Trevor, E-mail: tforsyth@ill.fr [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom)

    2008-05-01

    Preliminary neutron crystallographic data from the sweet protein thaumatin have been recorded using the LADI-III diffractometer at the Institut Laue Langevin (ILL). The results illustrate the feasibility of a full neutron structural analysis aimed at further understanding the molecular basis of the perception of sweet taste. Such an analysis will exploit the use of perdeuterated thaumatin. A preliminary neutron crystallographic study of the sweet protein thaumatin is presented. Large hydrogenated crystals were prepared in deuterated crystallization buffer using the gel-acupuncture method. Data were collected to a resolution of 2 Å on the LADI-III diffractometer at the Institut Laue Langevin (ILL). The results demonstrate the feasibility of a full neutron crystallographic analysis of this structure aimed at providing relevant information on the location of H atoms, the distribution of charge on the protein surface and localized water in the structure. This information will be of interest for understanding the specificity of thaumatin–receptor interactions and will contribute to further understanding of the molecular mechanisms underlying the perception of taste.

  8. Evidence for homosexuality gene

    Energy Technology Data Exchange (ETDEWEB)

    Pool, R.

    1993-07-16

    A genetic analysis of 40 pairs of homosexual brothers has uncovered a region on the X chromosome that appears to contain a gene or genes for homosexuality. When analyzing the pedigrees of homosexual males, the researcheres found evidence that the trait has a higher likelihood of being passed through maternal genes. This led them to search the X chromosome for genes predisposing to homosexuality. The researchers examined the X chromosomes of pairs of homosexual brothers for regions of DNA that most or all had in common. Of the 40 sets of brothers, 33 shared a set of five markers in the q28 region of the long arm of the X chromosome. The linkage has a LOD score of 4.0, which translates into a 99.5% certainty that there is a gene or genes in this area that predispose males to homosexuality. The chief researcher warns, however, that this one site cannot explain all instances of homosexuality, since there were some cases where the trait seemed to be passed paternally. And even among those brothers where there was no evidence that the trait was passed paternally, seven sets of brothers did not share the Xq28 markers. It seems likely that homosexuality arises from a variety of causes.

  9. Coordination in contractual relations: Some preliminary findings from the Malaysian housing industry

    Directory of Open Access Journals (Sweden)

    Suraya Ismail

    2008-12-01

    Full Text Available The traditional general procurement route found in many housing projects in Malaysia is conceptualized as a governance structure following the transaction cost economics (TCE approach. This approach has been used to examine governance structures in different economic sectors in several countries but evidence of its use in the context of developing countries is limited. This lack of evidence has prompted the authors to conduct a preliminary study to ascertain whether a TCE approach can explain construction governance structures in developing countries. This research does not discuss the trade-off that governs the choice of hybrids, market or hierarchies for organizing transactions. Rather, it takes advantage of existing research to substantiate the specific properties of hybrid organizations as governance structures. The main focus is coordination. Coordination is specified at two levels. At Level 1 is the coordination of specialization (i.e. the formation of the project team members and at Level 2 is the coordination mode of the contracting parties (client and contractor and the agents involved (the lead designer and project manage r. A case survey method was adopted. Preliminary findings seem to suggest that clients have used hierarchical themes in the contracts and high powered incentives to coordinate with in the contracting parties. The research findings suggest that all participants involved in the sample studied used governance structures symptomatic of a hybrid organization.

  10. Evidence-based clinical practice

    DEFF Research Database (Denmark)

    Gluud, Christian

    2002-01-01

    Evidence-based medicine combines the patient's preferences with clinical experience and the best research evidence. Randomized clinical trials are considered the most valid research design for evaluating health-care interventions. However, empirical research shows that intervention effects may be...... evidence in clinical practice. By investments in education, applied research, and The Cochrane Collaboration, evidence-based medicine may form a stronger basis for clinical practice....

  11. Evidence-Based Laboratory Medicine

    Institute of Scientific and Technical Information of China (English)

    Christopher P Price

    2004-01-01

    @@ Whilst there have been several definitions of Evidence-Based Medicine (EBM), the one given by David Sackett is probably the most accurate and well accepted; he stated that "evidence-based medicine is the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients"[1].

  12. Evidence on Inclusion

    DEFF Research Database (Denmark)

    Dyssegaard, Camilla Brørup; Larsen, Michael Søgaard

    The purpose of this publication is to examine existing research on inclusion to identify strategies of inclusion that have generated positive effects. To do so it is necessary to understand the effect of the applied strategies. One approach, which is being discussed, is to use evidence to determine...... which methods have proven more effective than others. The desire to gain insight into research on inclusion forms the basis of the current systematic review. The task was to determine which strategies primary research has found to be most effective for inclusion purposes. We have solved this task by...... addressing the existing research with the following question: What is the effect of including children with special needs in mainstream teaching in basic school, and which of the applied educational methods have proved to have a positive effect?...

  13. 37 CFR 1.480 - Demand for international preliminary examination.

    Science.gov (United States)

    2010-07-01

    ... TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing Provisions International Preliminary Examination § 1.480 Demand for international preliminary examination. (a... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Demand for...

  14. 37 CFR 1.482 - International preliminary examination fees.

    Science.gov (United States)

    2010-07-01

    ... OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing Provisions International Preliminary Examination § 1.482 International preliminary examination fees. (a) The... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false International...

  15. 37 CFR 1.484 - Conduct of international preliminary examination.

    Science.gov (United States)

    2010-07-01

    ... TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing Provisions International Preliminary Examination § 1.484 Conduct of international preliminary examination. (a... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Conduct of...

  16. Preliminary Opto-Mechanical Design for the X2000 Transceiver

    Science.gov (United States)

    Hemmati, H.; Page, N. A.

    2000-01-01

    Preliminary optical design and mechanical conceptual design for a 30 cm aperture transceiver are described. A common aperture is used for both transmit and receive. Special attention was given to off-axis and scattered light rejection and isolation of the receive channel from the transmit channel. Requirements, details of the design and preliminary performance analysis of the transceiver are provided.

  17. 40 CFR 8.6 - Preliminary environmental review.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Preliminary environmental review. 8.6 Section 8.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL ENVIRONMENTAL IMPACT ASSESSMENT OF NONGOVERNMENTAL ACTIVITIES IN ANTARCTICA § 8.6 Preliminary environmental review. (a) Unless...

  18. Preliminary design package for Sunair SEC-601 solar collector

    Energy Technology Data Exchange (ETDEWEB)

    1978-12-01

    This report presents the preliminary design of the Owens-Illinois mode Sunair SEC-601 tubular air solar collector. Information in this package includes the Subsystem Design and Development Approaches, hazard analysis, and detailed drawings available as the Preliminary Design Review.

  19. Breakthrough propulsion physics workshop preliminary results

    International Nuclear Information System (INIS)

    In August, 1997, a NASA workshop was held to assess the prospects emerging from physics that might lead to creating the ultimate breakthroughs in space transportation: propulsion that requires no propellant mass, attaining the maximum transit speeds physically possible, and breakthrough methods of energy production to power such devices. Because these propulsion goals are presumably far from fruition, a special emphasis was to identify affordable, near-term, and credible research that could make measurable progress toward these propulsion goals. Experiments and theories were discussed regarding the coupling of gravity and electromagnetism, vacuum fluctuation energy, warp drives and wormholes, and superluminal quantum tunneling. Preliminary results of this workshop are presented, along with the status of the Breakthrough Propulsion Physics program that conducted this workshop

  20. Preliminary Shielding Analysis for HCCB TBM Transport

    Science.gov (United States)

    Miao, Peng; Zhao, Fengchao; Cao, Qixiang; Zhang, Guoshu; Feng, Kaiming

    2015-09-01

    A preliminary shielding analysis on the transport of the Chinese helium cooled ceramic breeder test blanket module (HCCB TBM) from France back to China after being irradiated in ITER is presented in this contribution. Emphasis was placed on irradiation safety during transport. The dose rate calculated by MCNP/4C for the conceptual package design satisfies the relevant dose limits from IAEA that the dose rate 3 m away from the surface of the package containing low specific activity III materials should be less than 10 mSv/h. The change with location and the time evolution of dose rates after shutdown have also been studied. This will be helpful for devising the detailed transport plan of HCCB TBM back to China in the near future. supported by the Major State Basic Research Development Program of China (973 Program) (No. 2013GB108000)

  1. Helminthiases in Montes Claros. Preliminary survey

    Directory of Open Access Journals (Sweden)

    Rina Girard Kaminsky

    1976-04-01

    Full Text Available A preliminary survey was conducted for the presence of helminths in the city of Montes Claros, M. G., Brazil. Three groups of persons were examined by the direct smear, Kato thick film and MIFC techniques; one group by direct smear and Kato only. General findings were: a high prevalence of hookworm, followed by ascariasis, S. mansoni, S. stercoralis and very light infections with T. trichiurá. E. vermicularis and H. nana were ranking parasites at an orphanage, with some hookworm and S. mansoni infections as well. At a pig slaughter house, the dominant parasites were hookworm and S. mansoni. Pig cysticercosis was an incidental finding worth mentioning for the health hazard it represents for humans as well as an economic loss. From the comparative results between the Kato and the MIF the former proved itself again as a more sensitive and reliable concentration method for helminth eggs, of low cost and easy performance.

  2. Laryngeal electromyography in movement disorders: preliminary data

    Directory of Open Access Journals (Sweden)

    Kimaid Paulo A.T.

    2004-01-01

    Full Text Available This study describes preliminary laryngeal electromyography (LEMG data and botulinum toxin treatment in patients with dysphonia due to movement disorders. Twenty-five patients who had been clinically selected for botulinum toxin administration were examined, 19 with suspected laryngeal dystonia or spasmodic dysphonia (SD, 5 with vocal tremor, and 1 with Gilles de la Tourette syndrome (GTS. LEMG evaluations were performed before botulinum toxin administration using monopolar electrodes. Electromyography was consistent with dystonia in 14 patients and normal in 5, and differences in frequency suggesting essential tremor in 3 and Parkinson tremors in 2. The different LEMG patterns and significant improvement in our patients from botulinum toxin therapy has led us to perform laryngeal electromyography as a routine in UNICAMP movement disorders ambulatory.

  3. Breakthrough Propulsion Physics Workshop Preliminary Results

    Science.gov (United States)

    Millis, Marc G.

    1997-01-01

    In August, 1997, a NASA workshop was held to assess the prospects emerging from physics that might lead to creating the ultimate breakthroughs in space transportation: propulsion that requires no propellant mass, attaining the maximum transit speeds physically possible, and breakthrough methods of energy production to power such devices. Because these propulsion goals are presumably far from fruition, a special emphasis was to identify affordable, near-term, and credible research that could make measurable progress toward these propulsion goals. Experiments and theories were discussed regarding the coupling of gravity and electromagnetism, vacuum fluctuation energy, warp drives and wormholes, and superluminal quantum tunneling. Preliminary results of this workshop are presented, along with the status of the Breakthrough Propulsion Physics program that conducted this workshop.

  4. Atomic Energy Control Board vocabulary - preliminary edition

    International Nuclear Information System (INIS)

    This preliminary edition was prepared at the Board's request to help it establish a standardized terminology. It was produced by scanning the 99 French and English documents listed at the end of this Vocabulary. The documents include legislation concerning atomic energy and the transportation of radioactive materials, as well as the Board's publications, such as the Consultative Documents, Regulatory Documents and Notices. The terms included from the following areas are: radiation protection, reactor technology, nuclear fuel cycle, radioactive material packaging and transportation, radioactive waste management, uranium mines, and medical and industrial applications of radioelements. Also included are the titles of publications and the names of organizations and units. The vocabulary contains 2,589 concepts, sometimes accompanied by definitions, contexts or usage examples. Where terms have been standardized by the Canadian Committee for the Standardization of Nuclear Terminology, this has been indicated. Where possible, we have verified the terms using the TERMIUM, the Government of Canada Linguistic Data Bank. (author)

  5. Repository Subsurface Preliminary Fire Hazard Analysis

    International Nuclear Information System (INIS)

    This fire hazard analysis identifies preliminary design and operations features, fire, and explosion hazards, and provides a reasonable basis to establish the design requirements of fire protection systems during development and emplacement phases of the subsurface repository. This document follows the Technical Work Plan (TWP) (CRWMS M and O 2001c) which was prepared in accordance with AP-2.21Q, ''Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities''; Attachment 4 of AP-ESH-008, ''Hazards Analysis System''; and AP-3.11Q, ''Technical Reports''. The objective of this report is to establish the requirements that provide for facility nuclear safety and a proper level of personnel safety and property protection from the effects of fire and the adverse effects of fire-extinguishing agents

  6. Preliminary blade design using integrated computer codes

    Science.gov (United States)

    Ryan, Arve

    1988-12-01

    Loads on the root of a horizontal axis wind turbine (HAWT) rotor blade were analyzed. A design solution for the root area is presented. The loads on the blades are given by different load cases that are specified. To get a clear picture of the influence of different parameters, the whole blade is designed from scratch. This is only a preliminary design study and the blade should not be looked upon as a construction reference. The use of computer programs for the design and optimization is extensive. After the external geometry is set and the aerodynamic loads calculated, parameters like design stresses and laminate thicknesses are run through the available programs, and a blade design optimized on basis of facts and estimates used is shown.

  7. Preliminary investigations of piezoelectric based LED luminary

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Andersen, Michael A. E.; Meyer, Kaspar Sinding

    2011-01-01

    This paper presents a preliminary study of PT (Piezoelectric Transformer) based SMPS’s (Switch Mode Power Supplies) for LED luminary. The unique properties of PTs (efficiency, power density and EMI) make them highly suitable for this application. Power stage topologies, rectifiers circuits......, modulation schemes, LEDs and LED driving conditions are analyzed. A prototype radial mode PT optimized for ZVS (Zero Voltage Switching) is designed. FEM (Final Element Method) and measurements validates the PT design. A prototype PT based AC/DC converter operating from european mains is proposed. The...... prototype constitutes a light source equivalent to the 40 W incandescent bulb. Experimental results shows, that the prototype are capable of ZVS and dimming (the later trough use of burst mode control)....

  8. Preliminary dose assessment of the Chernobyl accident

    International Nuclear Information System (INIS)

    From the major accident at Unit 4 of the Chernobyl nuclear power station, a plume of airborne radioactive fission products was initially carried northwesterly toward Poland, thence toward Scandinavia and into Central Europe. Reports of the levels of radioactivity in a variety of media and of external radiation levels were collected in the Department of Energy's Emergency Operations Center and compiled into a data bank. Portions of these and other data which were obtained directly from published and official reports were utilized to make a preliminary assessment of the extent and magnitude of the external dose to individuals downwind from Chernobyl. Radioactive 131I was the predominant fission product. The time of arrival of the plume and the maximum concentrations of 131I in air, vegetation and milk and the maximum reported depositions and external radiation levels have been tabulated country by country. A large amount of the total activity in the release was apparently carried to a significant elevation. The data suggest that in areas where rainfall occurred, deposition levels were from ten to one-hundred times those observed in nearby ''dry'' locations. Sufficient spectral data were obtained to establish average release fractions and to establish a reference spectra of the other nuclides in the release. Preliminary calculations indicated that the collective dose equivalent to the population in Scandinavia and Central Europe during the first year after the Chernobyl accident would be about 8 x 106 person-rem. From the Soviet report, it appears that a first year population dose of about 2 x 107 person-rem (2 x 105 Sv) will be received by the population who were downwind of Chernobyl within the U.S.S.R. during the accident and its subsequent releases over the following week. 32 refs., 14 figs., 20 tabs

  9. No evidence for contagious yawning in lemurs.

    Science.gov (United States)

    Reddy, Rachna B; Krupenye, Christopher; MacLean, Evan L; Hare, Brian

    2016-09-01

    Among some haplorhine primates, including humans, relaxed yawns spread contagiously. Such contagious yawning has been linked to social bonds and empathy in some species. However, no studies have investigated contagious yawning in strepsirhines. We conducted an experimental study of contagious yawning in strepsirhines, testing ring-tailed and ruffed lemurs (n = 24) in a paradigm similar to one that has induced contagious yawning in haplorhines. First, in a control experiment, we investigated whether lemurs responded to projected video content in general (experiment 1). We showed them two videos to which we expected differential responses: one featured a terrestrial predator and the other a caretaker holding food. Next, to test for yawn contagion, we showed individual lemurs life-size video projections of groupmates and conspecific strangers yawning, and control footage of the same individuals at rest (experiment 2). Then, to examine whether a group context might enhance or allow for contagion, we exposed subjects to the same videos in a group setting (experiment 3). Lemurs produced alarm vocalizations and moved upward while viewing the predator, but not the caretaker, demonstrating that they do perceive video content meaningfully. However, lemurs did not yawn in response to yawning stimuli when tested alone, or with their groupmates. This study provides preliminary evidence that lemurs do not respond to yawning stimuli similarly to haplorhines, and suggests that this behavior may have evolved or become more exaggerated in haplorhines after the two major primate lineages split. PMID:27075549

  10. 75 FR 47307 - Center for Devices and Radiological Health 510(k) Working Group Preliminary Report and...

    Science.gov (United States)

    2010-08-05

    ... Decision Making Preliminary Report and Recommendations; Availability; Request for Comments AGENCY: Food and... of Science in Regulatory Decision Making. Volume I is entitled ``510(k) Working Group Preliminary... Regulatory Decision Making Preliminary Report and Recommendations.'' The recommendations contained in...

  11. Preliminary investigations of the thermal energy grid concept

    Energy Technology Data Exchange (ETDEWEB)

    Olszewski, M.

    1977-10-01

    This study examines, in a preliminary manner, the feasibility of the thermal grid concept. This concept essentially envisions the supply of heat to a long-distance transmission line from a dual-purpose nuclear or coal-fired power plant. The transmission line delivers heat to a subregion distribution network which delivers it to the consumer. District chilled water supply is also considered, using heat from the grid to power steam-turbine-driven water chillers. Candidate technologies for generation, transmission, and distribution of thermal energy are identified and assessed. Potential applications, including both industrial use and residential space conditioning and hot water supply, are evaluated. Results indicate that high-temperature hot-water transmission lines are favored for longer distances, while steam lines may be acceptable for shorter distances. It is also evident that thermal grid heat is more economically competitive for new applications, as opposed to retrofit situations, in the residential-commercial sector. The two applications are about equally feasible in the industrial sector. The results further indicate that thermal grid heat is most competitive in areas of high-heat-load density and expensive fuel costs. It appears that the thermal grid service area should include the industrial sector as a base load. The multifamily residential-commercial sector space and water heating loads can be added to the service area to maximize utilization of the transmission line and maintain low transmission costs. Supply of chilled water to the multifamily residential-commercial sector can also be included for new applications to increase the transmission line use factor. The thermal grid concept appears to be economically and technically feasible, when compared to oil and electric systems in the multifamily residential-commercial sector and coal- or oil-fired systems in the industrial sector, and should be explored in greater detail.

  12. Synthesizing Quantitative Evidence for Evidence-based Nursing: Systematic Review.

    Science.gov (United States)

    Oh, Eui Geum

    2016-06-01

    As evidence-based practice has become an important issue in healthcare settings, the educational needs for knowledge and skills for the generation and utilization of healthcare evidence are increasing. Systematic review (SR), a way of evidence generation, is a synthesis of primary scientific evidence, which summarizes the best evidence on a specific clinical question using a transparent, a priori protocol driven approach. SR methodology requires a critical appraisal of primary studies, data extraction in a reliable and repeatable way, and examination for validity of the results. SRs are considered hierarchically as the highest form of evidence as they are a systematic search, identification, and summarization of the available evidence to answer a focused clinical question with particular attention to the methodological quality of studies or the credibility of opinion and text. The purpose of this paper is to introduce an overview of the fundamental knowledge, principals and processes in SR. The focus of this paper is on SR especially for the synthesis of quantitative data from primary research studies that examines the effectiveness of healthcare interventions. To activate evidence-based nursing care in various healthcare settings, the best and available scientific evidence are essential components. This paper will include some examples to promote understandings. PMID:27349664

  13. Evidence of me” in evidence based medicine?

    OpenAIRE

    Lockwood, Susan

    2004-01-01

    Evidence based medicine provides independent, validated advice about treatment options, but does it take sufficient account of individual patients' values to provide them with an optimal health outcome?

  14. The Production Of Scientific Knowledge In Italy : Evidence In Theoretical, Applied And Technical Sciences.

    OpenAIRE

    Patrucco, Pier Paolo

    2006-01-01

    The paper presents preliminary empirical evidence on the production of scientific knowledge in Italy, in theoretical sciences (physics), applied sciences (chemistry) and technical sciences (engineer ing and petrology). It elaborates on an original dataset of publications and citations for 2,673 Italian researchers, distributed across 61 universities, covering the years between 1990 and 2004. According to a well-established tradition of studies in the economics of science, the results show tha...

  15. Financial constraints, risk taking and firm performance: Recent evidence from microfinance clients in Tanzania

    OpenAIRE

    Martijn Boermans; Daan Willebrands

    2012-01-01

    Financial constraints and risk taking are two well-established determinants of firm performance, however, no research analyzes how these variables are connected in the context of a high risk environment. Using data from microfinance clients in Tanzania, we derive a novel financial constraints measure and incorporate a psychometric risk taking scale. Results confirm the importance of access to finance and risk attitudes for business development. Also, we provide preliminary evidence for an int...

  16. The Production of Scientific Knowledge in Italy: Evidence in Theoretical, Applied and Technical Sciences

    OpenAIRE

    Patrucco, Pier Paolo

    2006-01-01

    The paper presents preliminary empirical evidence on the production of scientific knowledge in Italy, in theoretical sciences (physics), applied sciences (chemistry) and technical sciences (engineer ing and petrology). It elaborates on an original dataset of publications and citations for 2,673 Italian researchers, distributed across 61 universities, covering the years between 1990 and 2004. According to a well-established tradition of studies in the economics of science, the results show tha...

  17. NSLS-II Preliminary Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Dierker, S.

    2007-11-01

    Following the CD0 approval of the National Synchrotron Light Source II (NSLS-II) during August 2005, Brookhaven National Laboratory prepared a conceptual design for a worldclass user facility for scientific research using synchrotron radiation. DOE SC review of the preliminary baseline in December 2006 led to the subsequent CD1 approval (approval of alternative selection and cost range). This report is the documentation of the preliminary design work for the NSLS-II facility. The preliminary design of the Accelerator Systems (Part 1) was developed mostly based of the Conceptual Design Report, except for the Booster design, which was changed from in-storage-ring tunnel configuration to in external- tunnel configuration. The design of beamlines (Part 2) is based on designs developed by engineering firms in accordance with the specification provided by the Project. The conventional facility design (Part 3) is the Title 1 preliminary design by the AE firm that met the NSLS-II requirements. Last and very important, Part 4 documents the ES&H design and considerations related to this preliminary design. The NSLS-II performance goals are motivated by the recognition that major advances in many important technology problems will require scientific breakthroughs in developing new materials with advanced properties. Achieving this will require the development of new tools that will enable the characterization of the atomic and electronic structure, chemical composition, and magnetic properties of materials, at nanoscale resolution. These tools must be nondestructive, to image and characterize buried structures and interfaces, and they must operate in a wide range of temperatures and harsh environments. The NSLS-II facility will provide ultra high brightness and flux and exceptional beam stability. It will also provide advanced insertion devices, optics, detectors, and robotics, and a suite of scientific instruments designed to maximize the scientific output of the facility

  18. The Management of Computer Systems in Small Business: a preliminary analysis of the issues of importance to managers

    Directory of Open Access Journals (Sweden)

    Evan Patullock

    2005-11-01

    Full Text Available Research investigating the relative importance of issues facing organisations in their management of Information Systems (IS has grown rapidly since the early 1980s. However, this research has largely focused on large businesses, with little comparable data collected in the context of small businesses. This paper reports preliminary results from a pilot project investigating the relative importance of various IS concerns from the perspective of small business managers in the Albury-Wodonga region. Initial results confirm the operational focus of small business managers despite evidence of some concern with more strategic issues. In light of the preliminary nature of these findings, the paper concludes by identifying areas for further research.

  19. Limits of Evidence within EU

    Directory of Open Access Journals (Sweden)

    Monica Pocora

    2015-05-01

    Full Text Available The issue of admissibility of evidence has been regulated only very scarcely in the EU. Judicial cooperation in criminal matters has been embracing the increasing number of instruments, covering plethora of aspects, however, the field of admissibility of evidence remains almost untouched. Can the Area of Freedom, Security and Justice be called the Common Evidence Area? From the national perspective, the issue of admissibility of evidence is still subject to divergent solutions in the Member States, concerning the common law and continental law systems, i.e. the right of access to a lawyer. Thus, the paper aims to take into account the tendencies of legal rule in matter of admissibility of evidence, the dynamic of evidence movement within EU area.

  20. Preliminary Framework for Human-Automation Collaboration

    International Nuclear Information System (INIS)

    The Department of Energy's Advanced Reactor Technologies Program sponsors research, development and deployment activities through its Next Generation Nuclear Plant, Advanced Reactor Concepts, and Advanced Small Modular Reactor (aSMR) Programs to promote safety, technical, economical, and environmental advancements of innovative Generation IV nuclear energy technologies. The Human Automation Collaboration (HAC) Research Project is located under the aSMR Program, which identifies developing advanced instrumentation and controls and human-machine interfaces as one of four key research areas. It is expected that the new nuclear power plant designs will employ technology significantly more advanced than the analog systems in the existing reactor fleet as well as utilizing automation to a greater extent. Moving towards more advanced technology and more automation does not necessary imply more efficient and safer operation of the plant. Instead, a number of concerns about how these technologies will affect human performance and the overall safety of the plant need to be addressed. More specifically, it is important to investigate how the operator and the automation work as a team to ensure effective and safe plant operation, also known as the human-automation collaboration (HAC). The focus of the HAC research is to understand how various characteristics of automation (such as its reliability, processes, and modes) effect an operator's use and awareness of plant conditions. In other words, the research team investigates how to best design the collaboration between the operators and the automated systems in a manner that has the greatest positive impact on overall plant performance and reliability. This report addresses the Department of Energy milestone M4AT-15IN2302054, Complete Preliminary Framework for Human-Automation Collaboration, by discussing the two phased development of a preliminary HAC framework. The framework developed in the first phase was used as

  1. Astor Pass Seismic Surveys Preliminary Report

    Energy Technology Data Exchange (ETDEWEB)

    Louie, John [UNR; Pullammanappallil, Satish [Optim; Faulds, James; Eisses, Amy; Kell, Annie; Frary, Roxanna; Kent, Graham

    2011-08-05

    In collaboration with the Pyramid Lake Paiute Tribe (PLPT), the University of Nevada, Reno (UNR) and Optim re-processed, or collected and processed, over 24 miles of 2d seismic-reflection data near the northwest corner of Pyramid Lake, Nevada. The network of 2d land surveys achieved a near-3d density at the Astor Pass geothermal prospect that the PLPT drilled during Nov. 2010 to Feb. 2011. The Bureau of Indian Affairs funded additional seismic work around the Lake, and an extensive, detailed single-channel marine survey producing more than 300 miles of section, imaging more than 120 ft below the Lake bottom. Optim’s land data collection utilized multiple heavy vibrators and recorded over 200 channels live, providing a state-of-the-art reflection-refraction data set. After advanced seismic analysis including first-arrival velocity optimization and prestack depth migration, the 2d sections show clear fault-plane reflections, in some areas as deep as 4000 ft, tying to distinct terminations of the mostly volcanic stratigraphy. Some lines achieved velocity control to 3000 ft depth; all lines show reflections and terminations to 5000 ft depth. Three separate sets of normal faults appear in an initial interpretation of fault reflections and stratigraphic terminations, after loading the data into the OpendTect 3d seismic visualization system. Each preliminary fault set includes a continuous trace more than 3000 ft long, and a swarm of short fault strands. The three preliminary normal-fault sets strike northerly with westward dip, northwesterly with northeast dip, and easterly with north dip. An intersection of all three fault systems documented in the seismic sections at the end of Phase I helped to locate the APS-2 and APS-3 slimholes. The seismic sections do not show the faults connected to the Astor Pass tufa spire, suggesting that we have imaged mostly Tertiary-aged faults. We hypothesize that the Recent, active faults that produced the tufa through hotspring

  2. Preliminary geological suitability assessment for LILW disposal

    International Nuclear Information System (INIS)

    Due to the growing need for a final disposal of LILW, the final solution for the short-lived LILW is the key issue of radioactive waste management in Slovenia at the moment. ARAO - the Slovenian Agency for Radwaste Management - is intensely involved in the re-initiated site selection process for a LILW repository. In this new process we are trying to combine as best as possible the technical, geologically-led and the advocacy-site selection processes. By a combination of technical and volunteer approach to the site selection we wish to guarantee high public involvement and sufficient flexibility of the process to adapt to specific conditions or new circumstances while the project is ongoing. In the technical phase, our tendency is to retain a larger number of potential areas/sites. We also keep open the possibility of choosing the type of repository. The decision between the surface and underground option will be made only once the site has been defined. In accordance with the IAEA recommendations the site selection process is divided into four stages: the conceptual and planning stage, area survey stage, site characterisation stage and site confirmation stage. Last year the area survey stage was started. In the preliminary geological suitability assessment the required natural predisposition of Slovene territory was assessed in order to locate geologically suitable formations. The assessment of natural conditions of the system was based on consideration of the main geological, hydro-geological and seismotectonic conditions. It was performed with ARC/INFO technology. The results are compiled in a map, showing potential areas for underground and surface disposal of LILW in Slovenia. It has been established that there is a potential suitability for both surface and underground disposal on about 10 000 km2 of the Slovenian territory, which represents almost half of the entire Slovenian territory. These preliminary results are now being carefully re-examined. As an

  3. Preliminary Framework for Human-Automation Collaboration

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna Helene [Idaho National Lab. (INL), Idaho Falls, ID (United States); Le Blanc, Katya Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spielman, Zachary Alexander [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    The Department of Energy’s Advanced Reactor Technologies Program sponsors research, development and deployment activities through its Next Generation Nuclear Plant, Advanced Reactor Concepts, and Advanced Small Modular Reactor (aSMR) Programs to promote safety, technical, economical, and environmental advancements of innovative Generation IV nuclear energy technologies. The Human Automation Collaboration (HAC) Research Project is located under the aSMR Program, which identifies developing advanced instrumentation and controls and human-machine interfaces as one of four key research areas. It is expected that the new nuclear power plant designs will employ technology significantly more advanced than the analog systems in the existing reactor fleet as well as utilizing automation to a greater extent. Moving towards more advanced technology and more automation does not necessary imply more efficient and safer operation of the plant. Instead, a number of concerns about how these technologies will affect human performance and the overall safety of the plant need to be addressed. More specifically, it is important to investigate how the operator and the automation work as a team to ensure effective and safe plant operation, also known as the human-automation collaboration (HAC). The focus of the HAC research is to understand how various characteristics of automation (such as its reliability, processes, and modes) effect an operator’s use and awareness of plant conditions. In other words, the research team investigates how to best design the collaboration between the operators and the automated systems in a manner that has the greatest positive impact on overall plant performance and reliability. This report addresses the Department of Energy milestone M4AT-15IN2302054, Complete Preliminary Framework for Human-Automation Collaboration, by discussing the two phased development of a preliminary HAC framework. The framework developed in the first phase was used as the

  4. Preliminary results of steel containment vessel model test

    Energy Technology Data Exchange (ETDEWEB)

    Luk, V.K.; Hessheimer, M.F. [Sandia National Labs., Albuquerque, NM (United States); Matsumoto, T.; Komine, K.; Arai, S. [Nuclear Power Engineering Corp., Tokyo (Japan); Costello, J.F. [Nuclear Regulatory Commission, Washington, DC (United States)

    1998-04-01

    A high pressure test of a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of a steel containment vessel (SCV), representing an improved boiling water reactor (BWR) Mark II containment, was conducted on December 11--12, 1996 at Sandia National Laboratories. This paper describes the preliminary results of the high pressure test. In addition, the preliminary post-test measurement data and the preliminary comparison of test data with pretest analysis predictions are also presented.

  5. [Evidence and Lack of Evidence in the Treatment of Tinnitus].

    Science.gov (United States)

    Hesse, G

    2016-04-01

    A broad variety of therapeutic regimen is proposed, introduced and sold against tinnitus, but most of these approaches lack scientific validation and evidence. Up to date a causal, tinnitus eliminating therapy is not available. Most probably this will not be possible at all, as the mechanism of tinnitus generation are multiple and include peripheral as well as central or cortical reactions. Like in fashion and design however, therapeutic medical interventions against tinnitus come in waves again and again over the last decades, without being able to prove lasting and scientifically evident effects.This review presents, discusses and assesses almost all available therapies regarding their evidence. Evidence should include besides external evidence through publications and available data also internal evidence, e.g. including experience of the therapist and needs of the patients.Almost all interventions that try to influence the inner ear or the auditory cortex either pharmaceutically or by direct stimulation or modulation do not reach evidence. However, there are procedures that have proven to be effective and show at least certain degrees of evidence with proven strength of effect. These are habituation therapies and psychotherapeutic interventions like cognitive behavioural therapy, especially when they are combined with concrete measures to improve auditory perception like hearing-aids, cochlear implants or hearing-therapy. PMID:27128400

  6. When Lack of Evidence Is Evidence of Lack.

    Science.gov (United States)

    Pickering, Neil

    2015-12-01

    In their recent article "A Gentle Ethical Defence of Homeopathy," Levy, Gadd, Kerridge, and Komesaroff use the claim that "lack of evidence is not equivalent to evidence of lack" as a component of their ethical defence of homeopathy. In response, this article argues that they cannot use this claim to shore up their ethical arguments. This is because it is false. PMID:26631232

  7. Preliminary design of a tandem mirror reactor

    International Nuclear Information System (INIS)

    The purpose of this thesis is to examine the TARA mirror experiment as a possible tandem mirror reactor configuration. This is a preliminary study to size the coil structure based on using the smallest end cell axial length that physics and engineering allow, zeroing the central cell parallel currents and having interchange stability. The input powers are estimated for the final reactor design so a Q value may be estimated. The Q value is defined as the fusion power divided by the total injected power absorbed by the plasma. A computer study was performed on the effect of the transition size, the transition vertical spacing and transition current. These parameters affect the central cell parallel currents, the recircularization of the flux tube and the ratio of central cell beta to anchor beta needed for marginal stability. Two designs were identified. The first uses 100 keV and 13 keV neutral beams to pump the ions that trap in the thermal barrier. The Q value of this reactor is 11.3. The second reactor uses a pump beam at 40 keV. This energy is chosen because there is a resonance for the charge exchange cross section between D0 and He2+ at this energy, thus the alpha ash will be pumped along with the deuterium and tritium. The Q value of this reactor is 11.6

  8. Preliminary results from an advanced lighting controlstestbed

    Energy Technology Data Exchange (ETDEWEB)

    Avery, Douglas; Jennings, Judity; Rubinstein, Francis

    1998-03-01

    Preliminary results from a large-scale testbed of advanced lighting control technologies at the Phillip Burton Federal Building at 450 Golden Gate Ave. in San Francisco are presented. The first year objective of this project is to determine the sustainable energy savings and cost-effectiveness of different lighting control technologies compared to a portion of the building where only minimal controls are installed. The paper presents the analyzed results from six months of tests focused on accurately characterizing the energy savings potential of one type of daylight-linked lighting controls compared to the lighting in similar open-planned areas without dimming controls. After analyzing a half year;s data, we determined that the annual energy savings for this type of daylight- linked controls was 41% and 30% for the outer rows of lights on the South and North sides of the building, respectively. The annual energy savings dropped to 22% and 16% for the second row of lights for the South and North, respectively, and was negligible for the third rows of lights.

  9. Cockpit task management: A preliminary, normative theory

    Science.gov (United States)

    Funk, Ken

    1991-01-01

    Cockpit task management (CTM) involves the initiation, monitoring, prioritizing, and allocation of resources to concurrent tasks as well as termination of multiple concurrent tasks. As aircrews have more tasks to attend to due to reduced crew sizes and the increased complexity of aircraft and the air transportation system, CTM will become a more critical factor in aviation safety. It is clear that many aviation accidents and incidents can be satisfactorily explained in terms of CTM errors, and it is likely that more accidents induced by poor CTM practice will occur in the future unless the issue is properly addressed. The first step in understanding and facilitating CTM behavior was the development of a preliminary, normative theory of CTM which identifies several important CTM functions. From this theory, some requirements for pilot-vehicle interfaces were developed which are believed to facilitate CTM. A prototype PVI was developed which improves CTM performance and currently, a research program is under way that is aimed at developing a better understanding of CTM and facilitating CTM performance through better equipment and procedures.

  10. Preliminary assessment of valve IST effectiveness

    International Nuclear Information System (INIS)

    A preliminary review of inservice testing effectiveness for Code Class 1,2, and 3 valves at nuclear power plants was performed. These requirements are specified by the American Society of Mechanical Engineers Boiler and Pressure Vessel Code, Section XI, and the Operations and Maintenance Standard. The Institute of Nuclear Power Operations Nuclear Plant Reliability Data System (NPRDS) database was used to provide failure reports for these components for 1988 to 1992. This time period coincides with the issuance of Generic Letter 89-04, which resulted in a more consistent application of the requirements by the licensees. For this time period, 8,593 valve failures were identified. From the review of the NPRDS database, the primary failure causes and failure modes for motor-operated valves (MOV), air-operated valves (AOV), and check valves (CV) were identified. Solenoid-operated valves were not reviewed in this study. Plant testing programs were effective in identifying approximately 60% of the CV failures, 46% of the AOV failures, and 44% of the MOV failures

  11. Preliminary safety analysis for the Gorleben site

    International Nuclear Information System (INIS)

    A methodological approach for long-term safety analyses was applied in preparing the project ''Preliminary Safety Analysis of the Gorleben Site'' based on the German requirements for final disposal of heat generating radioactive waste. The approach included the description of the geological site and its future evolution coupled with a range of possible waste emplacement scenarios using site specific repository designs. The repository designs were developed to provide operational safety, long-term safety and retrieval / recovering of the waste to comply with the German requirements (BMU 2010). A safety concept for accomplishment of the radiological safety and its assessment was developed. Analysis of the integrity, fluid flows and radiological consequences were done and the performance of the system was assessed. If the present assumptions are confirmed by future research and development, the designed repository system for drift disposal was assessed to be robust. Further optimization of the present drift disposal design is possible in relation to gaseous radionuclide species and in relation to the technology of retrieval for the of borehole disposal design. This site specific safety analysis identified important tasks for research and development. The methodology and safety concept can be applied to other salt rock sites and can be transferred partially to clay sites.

  12. Tritium oxidation and exchange: preliminary studies

    International Nuclear Information System (INIS)

    The radiological hazard resulting from an exposure to either tritium oxide or tritium gas is discussed and the factors contributing to the hazard are presented. From the discussion it appears that an exposure to tritium oxide vapor is 104 to 105 times more hazardous than exposure to tritium gas. Present and future sources of tritium are briefly considered and indicate that most of the tritium has been and is being released as tritium oxide. The likelihood of gaseous releases, however, is expected to increase in the future, calling to task the present general release assumption that 100% of all tritium released is as oxide. Accurate evaluation of the hazards from a gaseous release will require a knowledge of the conversion rate of tritium gas to tritium oxide. An experiment for determining the conversion rate of tritium gas to tritium oxide is presented along with some preliminary data. The conversion rates obtained for low initial concentrations (10-4 to 10-1 mCi/ml) indicate the conversion may proceed more rapidly than would be expected from an extrapolation of previous data taken at higher concentrations

  13. Guidance for performing preliminary assessments under CERCLA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-09-01

    EPA headquarters and a national site assessment workgroup produced this guidance for Regional, State, and contractor staff who manage or perform preliminary assessments (PAs). EPA has focused this guidance on the types of sites and site conditions most commonly encountered. The PA approach described in this guidance is generally applicable to a wide variety of sites. However, because of the variability among sites, the amount of information available, and the level of investigative effort required, it is not possible to provide guidance that is equally applicable to all sites. PA investigators should recognize this and be aware that variation from this guidance may be necessary for some sites, particularly for PAs performed at Federal facilities, PAs conducted under EPA`s Environmental Priorities Initiative (EPI), and PAs at sites that have previously been extensively investigated by EPA or others. The purpose of this guidance is to provide instructions for conducting a PA and reporting results. This guidance discusses the information required to evaluate a site and how to obtain it, how to score a site, and reporting requirements. This document also provides guidelines and instruction on PA evaluation, scoring, and the use of standard PA scoresheets. The overall goal of this guidance is to assist PA investigators in conducting high-quality assessments that result in correct site screening or further action recommendations on a nationally consistent basis.

  14. Tritium oxidation and exchange: preliminary studies

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, J. E.; Easterly, C. E.

    1978-05-01

    The radiological hazard resulting from an exposure to either tritium oxide or tritium gas is discussed and the factors contributing to the hazard are presented. From the discussion it appears that an exposure to tritium oxide vapor is 10/sup 4/ to 10/sup 5/ times more hazardous than exposure to tritium gas. Present and future sources of tritium are briefly considered and indicate that most of the tritium has been and is being released as tritium oxide. The likelihood of gaseous releases, however, is expected to increase in the future, calling to task the present general release assumption that 100% of all tritium released is as oxide. Accurate evaluation of the hazards from a gaseous release will require a knowledge of the conversion rate of tritium gas to tritium oxide. An experiment for determining the conversion rate of tritium gas to tritium oxide is presented along with some preliminary data. The conversion rates obtained for low initial concentrations (10/sup -4/ to 10/sup -1/ mCi/ml) indicate the conversion may proceed more rapidly than would be expected from an extrapolation of previous data taken at higher concentrations (10/sup -1/ to 10/sup 2/ mCi/ml).

  15. ALMA Nutator Design and Preliminary Performance

    CERN Document Server

    Martin-Cocher, Pierre; Koch, Patrick M; Ni, Chih-Wen; Chen, Wei-Long; Chen, Ming-Tang; Raffin, Philippe; Ong, Chin-Long; Ho, Paul T P; Symmes, Arthur

    2013-01-01

    We report the past two years of collaboration between the di?erent actors on the ALMA nutator. Building on previous developments, the nutator has seen changes in much of the design. A high-modulus carbon ?fiber structure has been added on the back of the mirror in order to transfer the voice coils forces with less deformation, thus reducing delay problems due to flexing. The controller is now an off?-the-shelf National Instrument NI-cRIO, and the ampli?fier a class D servo drive from Advanced Motion Controls, with high peak power able to drive the coils at 300 Volts DC. The stow mechanism has been totally redesigned to improve on the repeatability and precision of the stow position, which is also the reference for the 26 bits Heidenhain encoders. This also improves on the accuracy of the stow position with wind loading. Finally, the software, written largely with National Instrument's LabView, has been developed. We will discuss these changes and the preliminary performances achieved to date. Keywords: ALMA, ...

  16. AGEB: preliminary 2008 energy balance for Germany

    International Nuclear Information System (INIS)

    According to preliminary calculations by the Arbeitsgemeinschaft Energiebilanzen (Energy Balances Working Group), the consumption of primary energy sources in Germany in 2008 rose by 1% from approx. 472 to nearly 478 million TCE. Especially the consumption of energy for space heating increased. The use of coal decreased. Electricity generation in nuclear power plants showed a clear increase. The share of renewable energies was determined by stable contributions by water power and an increase in wind power. In electricity generation, lignite was the most important energy source with approx. 150.0 billion kWh (23.5%), followed by nuclear power with 148.8 billion kWh (23.3%), hard coal with 128.5 billion kWh (20.1%), and natural gas with 83.0 billion kWh (13.0%). Among the renewable sources of energy, wind power rated 40.2 billion kWh (6.3%), followed by hydroelectric power with 27.0 billion kWh (4.2%). The other sources of renewable energy plus other sources and petroleum products contributed some 61.6 billion kWh (9.6%) to electricity generation. (orig.)

  17. PRELIMINARY SELECTION OF MGR DESIGN BASIS EVENTS

    International Nuclear Information System (INIS)

    The purpose of this analysis is to identify the preliminary design basis events (DBEs) for consideration in the design of the Monitored Geologic Repository (MGR). For external events and natural phenomena (e.g., earthquake), the objective is to identify those initiating events that the MGR will be designed to withstand. Design criteria will ensure that radiological release scenarios resulting from these initiating events are beyond design basis (i.e., have a scenario frequency less than once per million years). For internal (i.e., human-induced and random equipment failures) events, the objective is to identify credible event sequences that result in bounding radiological releases. These sequences will be used to establish the design basis criteria for MGR structures, systems, and components (SSCs) design basis criteria in order to prevent or mitigate radiological releases. The safety strategy presented in this analysis for preventing or mitigating DBEs is based on the preclosure safety strategy outlined in ''Strategy to Mitigate Preclosure Offsite Exposure'' (CRWMS M andO 1998f). DBE analysis is necessary to provide feedback and requirements to the design process, and also to demonstrate compliance with proposed 10 CFR 63 (Dyer 1999b) requirements. DBE analysis is also required to identify and classify the SSCs that are important to safety (ITS)

  18. Modeling Malaysia's Energy System: Some Preliminary Results

    Directory of Open Access Journals (Sweden)

    Ahmad M. Yusof

    2011-01-01

    Full Text Available Problem statement: The current dynamic and fragile world energy environment necessitates the development of new energy model that solely caters to analyze Malaysia’s energy scenarios. Approach: The model is a network flow model that traces the flow of energy carriers from its sources (import and mining through some conversion and transformation processes for the production of energy products to final destinations (energy demand sectors. The integration to the economic sectors is done exogeneously by specifying the annual sectoral energy demand levels. The model in turn optimizes the energy variables for a specified objective function to meet those demands. Results: By minimizing the inter temporal petroleum product imports for the crude oil system the annual extraction level of Tapis blend is projected at 579600 barrels per day. The aggregate demand for petroleum products is projected to grow at 2.1% year-1 while motor gasoline and diesel constitute 42 and 38% of the petroleum products demands mix respectively over the 5 year planning period. Petroleum products import is expected to grow at 6.0% year-1. Conclusion: The preliminary results indicate that the model performs as expected. Thus other types of energy carriers such as natural gas, coal and biomass will be added to the energy system for the overall development of Malaysia energy model.

  19. ALMA nutator design and preliminary performances

    Science.gov (United States)

    Martin-Cocher, Pierre; Ford, John; Koch, Patrick M.; Ni, Chih-Wen; Chen, Wei-Long; Chen, Ming-Tang; Raffin, Philippe; Ong, Ching-Long; Ho, Paul T. P.; Symmes, Arthur H.

    2012-09-01

    We report the past two years of collaboration between the different actors on the ALMA nutator. Building on previous developments, the nutator has seen changes in much of the design. A high-modulus carbon fiber structure has been added on the back of the mirror in order to transfer the voice coils forces with less deformation, thus reducing delay problems due to flexing. The controller is now an off-the-shelf National Instrument NI-cRIO, and the amplifier a class D servo drive from Advanced Motion Controls, with high peak power able to drive the coils at 300 Volts DC. The stow mechanism has been totally redesigned to improve on the repeatability and precision of the stow position, which is also the reference for the 26 bits Heidenhain encoders. This also improves on the accuracy of the stow position with wind loading. Finally, the software, written largely with National Instrument's LabView, has been developed. We will discuss these changes and the preliminary performance achieved to date.

  20. Viking first encounter of phobos: preliminary results.

    Science.gov (United States)

    Tolson, R H; Duxbury, T C; Born, G H; Christensen, E J; Diehl, R E; Farless, D; Hildebrand, C E; Mitchell, R T; Molko, P M; Morabito, L A; Palluconi, F D; Reichert, R J; Taraji, H; Veverka, J; Neugebauer, G; Findlay, J T

    1978-01-01

    During the last 2 weeks of February 1977, an intensive scientific investigation of the martian satellite Phobos was conducted by the Viking Orbiter-1 (VO-1) spacecraft. More than 125 television pictures were obtained during this period and infrared observations were made. About 80 percent of the illuminated hemisphere was imaged at a resolution of about 30 meters. Higher resolution images of limited areas were also obtained. Flyby distances within 80 kilometers of the surface were achieved. An estimate of the mass of Phobos (GM) was obtained by observing the effect of Phobos's gravity on the orbit of VO-1 as sensed by Earth-based radiometric tracking. Preliminary results indicate a value of GM of 0.00066 +/- 0.00012 cubic kilometer per second squared (standard deviation of 3) and a mean density of about 1.9 +/- 0.6 gram per cubic centimeter (standard deviation of 3). This low density, together with the low albedo and the recently determined spectral reflectance, suggest that Phobos is compositionally similar to type I carbonaceous chondrites. Thus, either this object formed in the outer part of the asteroid belt or Lewis's theory that such material cannot condense at 1.5 astronomical units is incorrect. The data on Phobos obtained during this first encounter period are comparable in quantity to all of the data on Mars returned by Mariner flights 4, 6, and 7. PMID:17841954

  1. Preliminary pharmacognostic screening of Achyranthes coynei stem

    Directory of Open Access Journals (Sweden)

    Vinayak Upadhya

    2015-01-01

    Full Text Available Achyranthes coynei is a rare, endemic perennial shrub reported from Karnataka and Maharashtra states of India. The plant is used to treat various disorders by folk healers and was proven to have antimicrobial and antioxidant properties. The present study was undertaken to evaluate microscopic and macroscopic characters of A. coynei stem, along with its physicochemical parameters. ProgRes ® CapturePro and Microsoft Excel were used for statistical analysis. Perennial, shrubby nature and woody stem were the distinguishing morphological characters observed. Transverse section (TS illustrated quadrangular outline of the stem and showed the presence of two types of trichomes on the thick-walled epidermis. TS also showed number of rosette calcium oxalates crystals; prismatic and microsphenoid crystals; conjoint, collateral open secondary vascular bundles; and two amphixylic medullary bundles in the pith. Ash and extractive values, micro and macro elements and nutritive factors were estimated in the present study. The presence of alkaloids, saponins and triterpenoids were observed in preliminary phytochemical screening. High-performance thin layer chromatographic analysis yielded different bands and also indicated the presence of oleanolic acid. The studied parameters for A. coynei stem will be useful for identification and authentication of the plant material.

  2. Preliminary pharmacognostic screening of Achyranthes coynei stem.

    Science.gov (United States)

    Upadhya, Vinayak; Ankad, Gireesh M; Pai, Sandeep R; Hegde, Shruti V; Hegde, Harsha V

    2015-01-01

    Achyranthes coynei is a rare, endemic perennial shrub reported from Karnataka and Maharashtra states of India. The plant is used to treat various disorders by folk healers and was proven to have antimicrobial and antioxidant properties. The present study was undertaken to evaluate microscopic and macroscopic characters of A. coynei stem, along with its physicochemical parameters. ProgRes(®) CapturePro and Microsoft Excel were used for statistical analysis. Perennial, shrubby nature and woody stem were the distinguishing morphological characters observed. Transverse section (TS) illustrated quadrangular outline of the stem and showed the presence of two types of trichomes on the thick-walled epidermis. TS also showed number of rosette calcium oxalates crystals; prismatic and microsphenoid crystals; conjoint, collateral open secondary vascular bundles; and two amphixylic medullary bundles in the pith. Ash and extractive values, micro and macro elements and nutritive factors were estimated in the present study. The presence of alkaloids, saponins and triterpenoids were observed in preliminary phytochemical screening. High-performance thin layer chromatographic analysis yielded different bands and also indicated the presence of oleanolic acid. The studied parameters for A. coynei stem will be useful for identification and authentication of the plant material. PMID:26167003

  3. The deuteron accelerator preliminary design for BISOL

    Science.gov (United States)

    Peng, S. X.; Zhu, F.; Wang, Z.; Gao, Y.; Guo, Z. Y.

    2016-06-01

    BISOL, which was named as Beijing_ISOL before (Cui et al., 2013), is the abbreviation of Beijing Isotope-Separation-On-Line neutron beam facility. It is proposed jointly by Peking University (PKU) and China Institute of Atomic Energy (CIAE) for basic science study and application. It is a double driven facility that can be driven by a reactor or a deuteron accelerator. The deuteron driver accelerator should accelerate the deuteron beam up to 40 MeV with maximum beam current of 10 mA. Proton beams up to 33 MeV and He2+ beams up to 81.2 MeV can also be accelerated in this accelerator. The accelerator can be operated on either CW (continuous waveform) or pulsed mode, and the ion energy can be adjusted in a wide range. The accelerator will also allow independent operation of the RIB (Radioactive Ion Beams) system. It will be mainly charged by PKU group. Details of the deuteron accelerator preliminary design for BISOL will be given in this paper.

  4. Preliminary Test for Constitutive Models of CAP

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Yeon Joon; Hong, Soon Joon; Hwang, Su Hyun; Lee, Keo Hyung; Kim, Min Ki; Lee, Byung Chul [FNC Tech., Seoul (Korea, Republic of); Ha, Sang Jun; Choi, Hoon [Korea Electric Power Research Institute, Daejeon (Korea, Republic of)

    2010-05-15

    The development project for the domestic design code was launched to be used for the safety and performance analysis of pressurized light water reactors. As a part of this project, CAP (Containment Analysis Package) code has been developing for the containment safety and performance analysis side by side with SPACE. The CAP code treats three fields (vapor, continuous liquid and dispersed drop) for the assessment of containment specific phenomena, and is featured by assessment capabilities in multi-dimensional and lumped parameter thermal hydraulic cell. Thermal hydraulics solver was developed and has a significant progress now. Implementation of the well proven constitutive models and correlations are essential in other for a containment code to be used with the generalized or optimized purposes. Generally, constitutive equations are composed of interfacial and wall transport models and correlations. These equations are included in the source terms of the governing field equations. In order to develop the best model and correlation package of the CAP code, various models currently used in major containment analysis codes, such as GOTHIC, CONTAIN2.0 and CONTEMPT-LT are reviewed. Several models and correlations were incorporated for the preliminary test of CAP's performance and test results and future plans to improve the level of execution besides will be discussed in this paper

  5. Preliminary evaluation of snubber single failures

    International Nuclear Information System (INIS)

    Snubbers are used in commercial nuclear power plants to restrain piping systems and equipment during dynamic stress events, such as seismic or fluid transients. They are usually installed at locations necessary to reduce high dynamic stresses and where using a rigid restraint would result in excessively high stresses during normal operating thermal transients. A preliminary evaluation of the safety implications of a potential single failure of a snubber used to support safety-related piping or equipment on nuclear power plants was conducted. From reviews of system support drawings, a candidate list of locations potentially vulnerable to a single snubber failure was prepared, and a screening process was used to rank snubber locations as having a high, medium, or low probability of causing a significant increase in the core damage frequency (CDF) should a single snubber fail to function. Two locations were ranked high, a Westinghouse PWR ice condenser main steam containment penetration and a General Electric BWR Mark I torus. Five locations were ranked medium and the remaining 31 were ranked as low or low-to-medium. The two locations ranked high and two locations ranked medium were chosen for a quantitative stress analysis. Of the four locations analyzed, only the PWR ice condenser main steam containment penetration was judged to be significantly susceptible to the failure of a single snubber

  6. Dientamoeba fragilis nella popolazione suina: indagini preliminari

    Directory of Open Access Journals (Sweden)

    Daniele Crotti

    2007-12-01

    Full Text Available Dientamoeba fragilis is a worldwide distributed protozoon which is now estimated responsible of enteric diseases in humans. A wide spectrum of intestinal symptoms has been described: diarrhoea (acute or prolonged, flatulence, abdominal pains, and not specific bowel syndrome; however, asymptomatic infection has been also reported. D. fragilis is still not well know because only the delicate trophozoite stage has been demonstrated in stool samples and definitive identification is based on permanent stains, usually not performed in ova and parasites (O&P examinations, in Italy.D. fragilis is difficult to cultivate but molecular techniques, such as PCR, appear promising for a sure diagnosis of this protozoan infection.The epidemiology of dientamoebiasis is not clear too, and this paper presents preliminary results concerning the presence of D. fragilis in swine faeces in order to evaluate the possible role of pigs as reservoir of the parasite. So, 121 stool specimens of swine population were examined using Giemsa permanent stain and D. fragilis was observed in 53 stool specimens (43.8%. Other consideratioona are reported too.

  7. Preliminary evaluation of implantable MOSFET radiation dosimeters

    International Nuclear Information System (INIS)

    In this paper, we report on measurements performed on a new prototype implantable radiation detector that uses metal-oxide semiconductor field effect transistors (MOSFETs) designed for in vivo dosimetry. The dosimeters, which are encapsulated in hermetically sealed glass cylinders, are used in an unbiased mode during irradiation, unlike other MOSFET detectors previously used in radiotherapy applications. They are powered by radio frequency telemetry for dose measurements, obviating the need for a power supply within each capsule. We have studied the dosimetric characteristics of these MOSFET detectors in vitro under irradiation from a 60Co source. The detectors show a dose reproducibility generally within 5% or better, with the main sources of error being temperature fluctuations occurring between the pre- and post-irradiation measurements as well as detector orientation. A better temperature-controlled environment leads to a reproducibility within 2%. Our preliminary in vitro results show clearly that true non-invasive in vivo dosimetry measurements are feasible and can be performed remotely using telemetric technology

  8. Preliminary studies of the biosynthesis of Austin

    International Nuclear Information System (INIS)

    Aspergillus ustus is one of the most prevalent fungi in the soil. There are now two reports of the occurrence of toxin-producing strains of this fungus on stored foodstuffs. In addition, strains of A. ustus have been isolated along with Penicillium species from samples of South African cheeses. All A. ustus isolates tested were judged to be highly toxic to ducklings when grown on maize meal, however, the toxins involved were not isolated. Austin is the trivial name of one of the toxins made by the fungus found on stored food. Preliminary work to studying the biosynthesis of this compound using 13C-labeled sodium acetate is reported here. The feasibility of the biosynthetic study was determined by feeding [1-14C]-sodium acetate to A. ustus cultures. The assignments made in the 13C-nmr spectrum of Austin are shown. The lowest dilution factor obtained in [1-14C]-sodium acetate feeding experiments was 14. This dilution factor is sufficiently low to allow a successful feeding of [1,2-13C2]-sodium acetate. A new metabolite of A. ustus, deacetylaustin, was isolated and identified. An alkaloid of unknown structure was also isolated from the fungus

  9. Preliminary Study of Fly Ash Ceramic Process

    International Nuclear Information System (INIS)

    Preliminary study of ceramic production process from two components ofwhich are fly ash and feldspar has been done. Aluminosilicate substancecontained in the fly ash is a basic material a former ceramic body, if itfired at the temperature of 1000 oC forms mullite (3Al2O3.2SiO2). Mulliteis a refractory material which is very stable at the temperature changing.This experiment studies the ceramic production process of two componentsnamely fly ash with particle size of oC.Steps of processes are making paste of fly ash and feldspar, making of greenpellets, and firing of pellets, physical analysis of ceramic including volumedecrease, lost ignition, porosity, density, water sorption, compressivestrength. The experiment result at firing temperature of 1000 oC were shownthat best composition at the weight ratio of fly ash to feldspar are 60/40and 50/50. It physical characteristic respectively are decrease of volume0.54 and 0.69 %, lost ignition = 11.98 and 11.78 %, porosity = 0.159 and0.155, density = 2.05 and 2.06 g/cm3, water sorption = 18.96 and 18.36 %,compressive strength = 24.82 and 24.79 kN/mm2. (author)

  10. Topology and phase transitions I. Preliminary results

    International Nuclear Information System (INIS)

    In this first paper, we demonstrate a theorem that establishes a first step toward proving a necessary topological condition for the occurrence of first- or second-order phase transitions: we prove that the topology of certain submanifolds of configuration space must necessarily change at the phase transition point. The theorem applies to smooth, finite-range and confining potentials V bounded below, describing systems confined in finite regions of space with continuously varying coordinates. The relevant configuration space submanifolds are both the level sets {Σv:=VN-1(v)}velementofR of the potential function VN and the configuration space submanifolds enclosed by the Σv defined by {Mv:=VN-1((-∞,v])}velementofR, which are labeled by the potential energy value v, and where N is the number of degrees of freedom. The proof of the theorem proceeds by showing that, under the assumption of diffeomorphicity of the equipotential hypersurfaces {Σv}velementofR, as well as of the {Mv}velementofR, in an arbitrary interval of values for v-bar =v/N, the Helmholtz free energy is uniformly convergent in N to its thermodynamic limit, at least within the class of twice differentiable functions, in the corresponding interval of temperature. This preliminary theorem is essential to prove another theorem-in (paper II)-which makes a stronger statement about the relevance of topology for phase transitions

  11. Preliminary description of the transportation operations systems

    International Nuclear Information System (INIS)

    This document presents a preliminary description of the transportation operations systems designed to ship spent fuel and high-level waste (HLW) from waste generator sites to authorized waste receiving facilities. It is an initial effort to define the operations system and identifies the activities and system components necessary to provide complete transportation capability. It is intended that this be a project level working document to facilitate dialog for further identification of system elements and functional requirements. This process will lead to issuance of a System Requirements and Description (SRD) document for the transportation operations systems and will identify detailed system functional requirements, performance criteria, and functional interfaces. The transportation system is quite complex and is influenced by a large number of external factors and interfaces. Some of these interfaces (such as the repository) are just now being developed. Others (such as utility-handling capabilities) are currently in existence and must be accommodated or modified. Additionally, the allocation of requirements is likewise both developing (with the repository) and somewhat fixed. 16 refs., 15 figs., 12 tabs

  12. Evidence and Ethics (Editorial

    Directory of Open Access Journals (Sweden)

    Alison Brettle

    2012-12-01

    Full Text Available Welcome to the December issue of EBLIP, the final issue of my first year as Editor-in-Chief. A year which I have thoroughly enjoyed and one where the fears over what to write in my editorials haven’t materialised. This quarter, ethics has featured quite heavily in my working life so I decided to make this the topic of the editorial, sharing some of my thoughts regarding evidence, ethics and how ethical principles are implemented within the EBLIP journal.Ethics are “principles of conduct or standards of behaviour governing an individual or profession” (Library and Information Science Editorial Committee, 2010, and as individuals or professionals we may be governed by various ethical codes. As I'm sure you know, EBLIP originated in the health domain, where ethical values and ethical research feature strongly. Indeed, by its formal definition, research cannot take place unless “ethical approval” from an appropriate committee has been granted. The practicalities of taking research through the ethical approval process can often be time consuming, and those involved in research need to bear this in mind when planning a project. Each committee will have a slightly different form and process (which can add to the frustration of the researcher, but basically will make their decision to approve on the basis that the research includes obtaining informed consent from participants (i.e., participants know what the research is about and what their involvement will mean; that the research will not cause harm to participants; that confidentiality will be maintained; and that the research undertaken is methodologically rigorous and worthwhile. Preparing a proposal for ethical approval, whilst time consuming, makes the researcher think about all aspects of the research and how it is going to be operationalized, which can save lots of time and effort in the long run and may well also improve the research design. These principles are the same whatever

  13. Evidence-based clinical practice

    DEFF Research Database (Denmark)

    Garattini, Silvio; Jakobsen, Janus C; Wetterslev, Jørn;

    2016-01-01

    Using the best quality of clinical research evidence is essential for choosing the right treatment for patients. How to identify the best research evidence is, however, difficult. In this narrative review we summarise these threats and describe how to minimise them. Pertinent literature was consi...

  14. rf duress alarms: market survey and preliminary characterization

    International Nuclear Information System (INIS)

    This report represents the first phase of the duress alarm studies. Presented here are the results of an extensive market survey and some preliminary observations on the effectiveness of many system components

  15. Preliminary fishery management report : Des Lacs National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — A study of fishery management at Des Lacs National Wildlife Refuge was conducted from June 18 to 20, 1952. This brief preliminary report will serve to highlight the...

  16. High brightness symmetric emittance rf photoinjector preliminary design report

    International Nuclear Information System (INIS)

    A preliminary design for a high bunch charge (8 nC), low emittance (z = 1 mm. Electrical and beam dynamical aspects of the photoinjector design are presented. A description of the proposed experimental program is included

  17. Preliminary design activities for solar heating and cooling systems

    Science.gov (United States)

    1978-01-01

    Information on the development of solar heating and cooling systems is presented. The major emphasis is placed on program organization, system size definition, site identification, system approaches, heat pump and equipment design, collector procurement, and other preliminary design activities.

  18. NOS CO-OPS Water Level Data, Preliminary, 1-Minute

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has recent, preliminary (not quality-controlled), 1-minute, water level (tide) data from NOAA NOS Center for Operational Oceanographic Products and...

  19. 33 CFR 1.07-25 - Preliminary matters.

    Science.gov (United States)

    2010-07-01

    ... GENERAL PROVISIONS Enforcement; Civil and Criminal Penalty Proceedings § 1.07-25 Preliminary matters. (a... issue will preclude its consideration. (b) The right to a hearing is waived if the party does not...

  20. Preliminary Report on Seaside Sparrow Population Genetics Project

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is a preliminary report on a genetic variation study that was conducted at St. Vincent National Wildlife Refuge. Blood samples were taken from 57 Seaside...

  1. 1954 preliminary appraisal landuse map : Quivira National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This map is from the 1954 Preliminary appraisal report for the Great Salt Marsh National Wildlife Refuge, known today as Quivira National Wildlife Refuge, in...

  2. Ouarkziz Impact Structure, Algeria: Preliminary Petrographic and Geochemical Studies

    Science.gov (United States)

    Sahoui, R.; Belhai, D.

    2015-07-01

    Ouarkziz impact crater in Algeria is set in Namurian lower limestone and marls with gypsum. We present here preliminary petrographic and geochemical studies of the rocks and breccias forming the rings ans the central area of the structure.

  3. Scope and purpose of the preliminary planning work

    International Nuclear Information System (INIS)

    The results of preliminary planning work are usually expressed in a number of recommendations covering mainly: long-term national policy in the field of energy resources and selection of projects to be further studied at the feasibility level. Moreover, recommendations on further actions are made including: inventory of generation and transmission facilities recommended for the implementation in order to meet the load forecasted for medium-term period, preparation of a preliminary calender of decisions to be taken for the implementation of the projects recommended, preparation of a preliminary construction schedule, preparation of a preliminary investment program, preparation of a program of necessary engineering works, and performance of study on electricity rates which would adjust existing tariffs to proposed development program of the utility. (HP)

  4. NOS CO-OPS Water Level Data, Preliminary, 6-Minute

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has recent, preliminary (not quality-controlled), 6-minute, water level (tide) data from NOAA NOS Center for Operational Oceanographic Products and...

  5. PRELIMINARY COST ESTIMATES OF POLLUTION CONTROL TECHNOLOGIES FOR GEOTHERMAL DEVELOPMENTS

    Science.gov (United States)

    This report provides preliminary cost estimates of air and water pollution control technologies for geothermal energy conversion facilities. Costs for solid waste disposal are also estimated. The technologies examined include those for control of hydrogen sulfide emissions and fo...

  6. Preliminary survey of biodiversity in New Chicago Marsh

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — During the late winter and early springs 1995, we conducted a preliminary survey of biodiversity in New Chicago Marsh (NCM), at the south end of San Francisco Bay,...

  7. Research on Optimization Strategy of Missile Preliminary Design

    Institute of Scientific and Technical Information of China (English)

    SUZi-jian; ZHONGYi-fang

    2004-01-01

    Two system optimization architectures are proposed for missile system preliminary design, taking into account aerodynamics, weights and sizing, propulsion and trajectory.Approximation methods are investigated in order to reduce problem dimensionality and to improve the efficiency of optimization process.

  8. rf duress alarms: market survey and preliminary characterization

    Energy Technology Data Exchange (ETDEWEB)

    Draper, B.L.

    1979-05-01

    This report represents the first phase of the duress alarm studies. Presented here are the results of an extensive market survey and some preliminary observations on the effectiveness of many system components.

  9. InRidge program: Preliminary results from the first cruise

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R.; Murthy, K.S.R.; Iyer, S.D.; Rao, M.M.M.; Banerjee, R.; Subrahmanyam, A.S.; Shirodkar, P.V.; Ghose, I.

    thicknesses and fresh basaltic nuclei. Preliminary studies indicate a possible mixed hydrothermal and hydrogenous source for these nodules. The water column was also sampled at the Vema and Vityaz transform fault areas....

  10. Wrinkle Ridges in Aeolis Dorsa, Mars: Preliminary Mapping

    Science.gov (United States)

    Borden, R. M.; Burr, D. M.

    2016-06-01

    Previous work has interpreted wrinkle ridges as compressional landforms caused by movement along blind thrust faults. Our preliminary mapping in the Aeolis Dorsa, Mars has identified widely distributed wrinkle ridges, suggesting episodic contraction.

  11. Preliminary work of a smart needling project

    Science.gov (United States)

    Yan, Kaiguo; Liu, Tien-I.; Ling, Keck Voon; Yu, Yan; O'Dell, Walter; Sing, Ng Wan

    2005-04-01

    Precise needle placement is vital for the success of a wide variety of percutaneous surgical procedures. Insertions into soft tissues can be difficult to learn and to perform, due to tissue deformation, needle deflection and limited visual feedback. Little quantitative information is known about the interaction between needles and soft tissues during puncture. We are carrying out a "smart needling" project in which a fairly long, but slender biopsy needle will be controlled to hit the target that is inside human body, automatically and precisely. This paper reports the preliminary work which is to prove that translational oscillation of the needle can reduce target movement, and at the same time to find the optimal settings of the important factors that will produce the least target movement. The experiment platform comprises of an oscillatory needle restricted to translate horizontally. A position-trackable catheter was embedded in the phantom to act as the target. Two-Level factorial design was adopted and an exploratory data analysis (EDA) approach was used for analysis. The final results showed that oscillation at high frequency band from 2kHz to 20kHz can reduce target movement. Translation speed, oscillation frequency and amplitude are all important factors. But phantoms with different elasticities may have different best settings of these factors. For example, for soft phantoms, lower frequency, higher speed and smaller amplitude are desired for minimal target movement. Optimization searching engine will be designed correspondingly to control the needle in optimal working conditions that can produce minimal target movement.

  12. 3T MRI neurography: preliminary experience

    International Nuclear Information System (INIS)

    Purpose. Demonstrate the advantages of the Ideal (Iterative Decomposition of water and fat with Echo Asymmetry and Least-squares estimation) sequence in the evaluation of peripheral nerves, brachial plexus and lumbar plexus, for the diagnosis of compression or entrapment neuropathies, non-entrapment neuropathies, and the underlying conditions. The Ideal sequence provides 4 types of images from a single acquisition, allowing uniform fat or water suppression and in phase/out of phase images of water, fat or a combination of both. Materials and Methods. This is a retrospective study, from January 2011 to June 2011. Eleven neurographies were performed on 3T MRI (HDX 3T, GE Healthcare, USA), with 8-channel phased array coils on sagittal and coronal planes, with 1.2-0 mm slices with no gap, axial 3D spoiled gradient recalled (SPGR) T , with 1-0-mm slice thickness with and without gadolinium injection and variable field of view (FOV) according to the nerve or plexus to explore. Results. We found 2 schwannomas (brachial plexus and sciatic nerve), 1 neuritis (compression to median nerve), 2 cases of multiple neurofibromas (lumbosacral plexus, sciatic nerve, brachial plexus), 3 traumatic neuromas (peroneal nerve) and 1 pseudomeningocele avulsion (brachial plexus), and 2 with no structural alterations (lumbosacral plexus and peroneal nerve). Conclusion. In this preliminary experience, the use of highresolution sequences in magnetic resonance imaging neurography studies provided excellent signal homogeneity, improving the recognition of the nerve structure and signal, the identification of anatomical variations, and causes of neuropathy, as well as the characterization of denervation changes of the affected muscle groups. (authors)

  13. Preliminary images from an adaptive imaging system.

    Science.gov (United States)

    Griffiths, J A; Metaxas, M G; Pani, S; Schulerud, H; Esbrand, C; Royle, G J; Price, B; Rokvic, T; Longo, R; Asimidis, A; Bletsas, E; Cavouras, D; Fant, A; Gasiorek, P; Georgiou, H; Hall, G; Jones, J; Leaver, J; Li, G; Machin, D; Manthos, N; Matheson, J; Noy, M; Ostby, J M; Psomadellis, F; van der Stelt, P F; Theodoridis, S; Triantis, F; Turchetta, R; Venanzi, C; Speller, R D

    2008-06-01

    I-ImaS (Intelligent Imaging Sensors) is a European project aiming to produce real-time adaptive X-ray imaging systems using Monolithic Active Pixel Sensors (MAPS) to create images with maximum diagnostic information within given dose constraints. Initial systems concentrate on mammography and cephalography. In our system, the exposure in each image region is optimised and the beam intensity is a function of tissue thickness and attenuation, and also of local physical and statistical parameters in the image. Using a linear array of detectors, the system will perform on-line analysis of the image during the scan, followed by optimisation of the X-ray intensity to obtain the maximum diagnostic information from the region of interest while minimising exposure of diagnostically less important regions. This paper presents preliminary images obtained with a small area CMOS detector developed for this application. Wedge systems were used to modulate the beam intensity during breast and dental imaging using suitable X-ray spectra. The sensitive imaging area of the sensor is 512 x 32 pixels 32 x 32 microm(2) in size. The sensors' X-ray sensitivity was increased by coupling to a structured CsI(Tl) scintillator. In order to develop the I-ImaS prototype, the on-line data analysis and data acquisition control are based on custom-developed electronics using multiple FPGAs. Images of both breast tissues and jaw samples were acquired and different exposure optimisation algorithms applied. Results are very promising since the average dose has been reduced to around 60% of the dose delivered by conventional imaging systems without decrease in the visibility of details. PMID:18291697

  14. Preliminary Evaluation of a New Cosmology Curriculum

    Science.gov (United States)

    Coble, Kimberly A.; Martin, Dominique; Hayes, Patrycia; Targett, Tom; Bailey, Janelle M.; Cominsky, Lynn R.

    2015-01-01

    Informed by our research on student understanding of cosmology, The Big Ideas in Cosmology is an immersive set of web-based learning modules that integrates text, figures, and visualizations with short and long interactive tasks and real cosmological data. This enables the transformation of general education astronomy and cosmology classes from primarily lecture and book-based courses to a more engaging format that builds important STEM skills.During the spring 2014 semester, we field-tested a subset of chapters with the general education astronomy and cosmology classes at Sonoma State University in a flipped-classroom format. We administered pre and post content and attitude assessments in the two flipped classes as well as two lecture classes. The majority of cosmology students had taken astronomy before whereas the astronomy students had not.When switching to an active mode of learning (e.g., flipped classroom instead of lecture), many instructors report pushback from students. We saw this effect from students in course evaluations, who reported dissatisfaction with "having to do more work." However, the students in the flipped section in astronomy made greater gains on the multiple choice content assessment than the students in either of the two lecture sections. On the attitude assessment (the CLASS), the cosmology students made a small shift toward more expert-like opinions. Preliminary results from open-ended content surveys indicate that, prior to instruction, students had difficulty answering 'why' or 'how do we know' questions; that post-instruction, students are less likely to respond "I don't know" or to leave an answer blank; and that students using the modules made gains in their content knowledge.Module development was supported by NASA ROSES E/PO Grant #NNXl0AC89G, the Illinois Space Grant Consortium, the Fermi E/PO program, Sonoma State University's Space Science Education and Public Outreach Group, and Great River Technology

  15. Methodology for Preliminary Design of Electrical Microgrids

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Richard P. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Stamp, Jason E. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Eddy, John P. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Henry, Jordan M [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Munoz-Ramos, Karina [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Abdallah, Tarek [U.S. Army Corps of Engineers, Washington, DC (United States)

    2015-09-30

    Many critical loads rely on simple backup generation to provide electricity in the event of a power outage. An Energy Surety Microgrid TM can protect against outages caused by single generator failures to improve reliability. An ESM will also provide a host of other benefits, including integration of renewable energy, fuel optimization, and maximizing the value of energy storage. The ESM concept includes a categorization for microgrid value proposi- tions, and quantifies how the investment can be justified during either grid-connected or utility outage conditions. In contrast with many approaches, the ESM approach explic- itly sets requirements based on unlikely extreme conditions, including the need to protect against determined cyber adversaries. During the United States (US) Department of Defense (DOD)/Department of Energy (DOE) Smart Power Infrastructure Demonstration for Energy Reliability and Security (SPIDERS) effort, the ESM methodology was successfully used to develop the preliminary designs, which direct supported the contracting, construction, and testing for three military bases. Acknowledgements Sandia National Laboratories and the SPIDERS technical team would like to acknowledge the following for help in the project: * Mike Hightower, who has been the key driving force for Energy Surety Microgrids * Juan Torres and Abbas Akhil, who developed the concept of microgrids for military installations * Merrill Smith, U.S. Department of Energy SPIDERS Program Manager * Ross Roley and Rich Trundy from U.S. Pacific Command * Bill Waugaman and Bill Beary from U.S. Northern Command * Melanie Johnson and Harold Sanborn of the U.S. Army Corps of Engineers Construc- tion Engineering Research Laboratory * Experts from the National Renewable Energy Laboratory, Idaho National Laboratory, Oak Ridge National Laboratory, and Pacific Northwest National Laboratory

  16. Finite element analyses of CCAT preliminary design

    Science.gov (United States)

    Sarawit, Andrew T.; Kan, Frank W.

    2014-07-01

    This paper describes the development of the CCAT telescope finite element model (FEM) and the analyses performed to support the preliminary design work. CCAT will be a 25 m diameter telescope operating in the 0.2 to 2 mm wavelength range. It will be located at an elevation of 5600 m on Cerro Chajnantor in Northern Chile, near ALMA. The telescope will be equipped with wide-field cameras and spectrometers mounted at the two Nasmyth foci. The telescope will be inside an enclosure to protect it from wind buffeting, direct solar heating, and bad weather. The main structures of the telescope include a steel Mount and a carbon-fiber-reinforced-plastic (CFRP) primary truss. The finite element model developed in this study was used to perform modal, frequency response, seismic response spectrum, stress, and deflection analyses of telescope. Modal analyses of telescope were performed to compute the structure natural frequencies and mode shapes and to obtain reduced order modal output at selected locations in the telescope structure to support the design of the Mount control system. Modal frequency response analyses were also performed to compute transfer functions at these selected locations. Seismic response spectrum analyses of the telescope subject to the Maximum Likely Earthquake were performed to compute peak accelerations and seismic demand stresses. Stress analyses were performed for gravity load to obtain gravity demand stresses. Deflection analyses for gravity load, thermal load, and differential elevation drive torque were performed so that the CCAT Observatory can verify that the structures meet the stringent telescope surface and pointing error requirements.

  17. Analytical Chemistry Core Capability Assessment - Preliminary Report

    Energy Technology Data Exchange (ETDEWEB)

    Barr, Mary E. [Los Alamos National Laboratory; Farish, Thomas J. [Los Alamos National Laboratory

    2012-05-16

    The concept of 'core capability' can be nebulous one. Even at a fairly specific level, where core capability equals maintaining essential services, it is highly dependent upon the perspective of the requestor. Samples are submitted to analytical services because the requesters do not have the capability to conduct adequate analyses themselves. Some requests are for general chemical information in support of R and D, process control, or process improvement. Many analyses, however, are part of a product certification package and must comply with higher-level customer quality assurance requirements. So which services are essential to that customer - just those for product certification? Does the customer also (indirectly) need services that support process control and improvement? And what is the timeframe? Capability is often expressed in terms of the currently utilized procedures, and most programmatic customers can only plan a few years out, at best. But should core capability consider the long term where new technologies, aging facilities, and personnel replacements must be considered? These questions, and a multitude of others, explain why attempts to gain long-term consensus on the definition of core capability have consistently failed. This preliminary report will not try to define core capability for any specific program or set of programs. Instead, it will try to address the underlying concerns that drive the desire to determine core capability. Essentially, programmatic customers want to be able to call upon analytical chemistry services to provide all the assays they need, and they don't want to pay for analytical chemistry services they don't currently use (or use infrequently). This report will focus on explaining how the current analytical capabilities and methods evolved to serve a variety of needs with a focus on why some analytes have multiple analytical techniques, and what determines the infrastructure for these analyses. This

  18. Preliminary design of a universal Martian lander

    Science.gov (United States)

    Norman, Timothy L.; Gaskin, David E.; Adkins, Sean; Gunawan, Mary; Johnson, Raquel; Macdonnell, David; Parlock, Andrew; Sarick, John; Bodwell, Charles; Hashimoto, Kouichi

    1993-01-01

    In the next 25 years, mankind will be undertaking yet another giant leap forward in the exploration of the solar system: a manned mission to Mars. This journey will provide important information on the composition and history of both Mars and the Solar System. A manned mission will also provide the opportunity to study how humans can adapt to long term space flight conditions and the Martian environment. As part of the NASA/USRA program, nineteen West Virginia University students conducted a preliminary design of a manned Universal Martian Lander (UML). The UML's design will provide a 'universal' platform, consisting of four modules for living and laboratory experiments and a liquid-fuel propelled Manned Ascent Return Vehicle (MARV). The distinguishing feature of the UML is the 'universal' design of the modules which can be connected to form a network of laboratories and living quarters for future missions thereby reducing development and production costs. The WVU design considers descent to Mars from polar orbit, a six month surface stay, and ascent for rendezvous. The design begins with an unmanned UML landing at Elysium Mons followed by the manned UML landing nearby. During the six month surface stay, the eight modules will be assembled to form a Martian base where scientific experiments will be performed. The mission will also incorporate hydroponic plant growth into a Controlled Ecological Life Support System (CELSS) for water recycling, food production, and to counteract psychological effects of living on Mars. In situ fuel production for the MARV will be produced from gases in the Martian atmosphere. Following surface operations, the eight member crew will use the MARV to return to the Martian Transfer Vehicle (MTV) for the journey home to Earth.

  19. Analytical Chemistry Core Capability Assessment - Preliminary Report

    International Nuclear Information System (INIS)

    The concept of 'core capability' can be nebulous one. Even at a fairly specific level, where core capability equals maintaining essential services, it is highly dependent upon the perspective of the requestor. Samples are submitted to analytical services because the requesters do not have the capability to conduct adequate analyses themselves. Some requests are for general chemical information in support of R and D, process control, or process improvement. Many analyses, however, are part of a product certification package and must comply with higher-level customer quality assurance requirements. So which services are essential to that customer - just those for product certification? Does the customer also (indirectly) need services that support process control and improvement? And what is the timeframe? Capability is often expressed in terms of the currently utilized procedures, and most programmatic customers can only plan a few years out, at best. But should core capability consider the long term where new technologies, aging facilities, and personnel replacements must be considered? These questions, and a multitude of others, explain why attempts to gain long-term consensus on the definition of core capability have consistently failed. This preliminary report will not try to define core capability for any specific program or set of programs. Instead, it will try to address the underlying concerns that drive the desire to determine core capability. Essentially, programmatic customers want to be able to call upon analytical chemistry services to provide all the assays they need, and they don't want to pay for analytical chemistry services they don't currently use (or use infrequently). This report will focus on explaining how the current analytical capabilities and methods evolved to serve a variety of needs with a focus on why some analytes have multiple analytical techniques, and what determines the infrastructure for these analyses. This information will be

  20. Stable isotope variations in benthic primary producers along the Bosphorus (Turkey): A preliminary study

    International Nuclear Information System (INIS)

    Highlights: • Nitrogen pollution along the Bosphorus Strait was investigated. • C and N isotopic and elemental analyses on benthic primary producers were performed. • δ15N decreased, while δ13C and N% increased from north to south along the Strait. • Ulva lactuca was more useful than epiphytes as indicator of nitrogen pollution. • Preliminary isotopic analyses on resident organisms are useful monitoring tools. - Abstract: The Bosphorus Strait is a dynamic and complex system. Recent evidences showed nitrogen and heavy metal concentrations to follow opposite patterns across the Strait, suggesting a complex spatial organisation of the anthropogenic disturbance in this system. Here, we provide isotopic information on the origin and transportation of dissolved nitrogen along the Bosphorus. C and N isotopic and elemental analyses were performed on specimens of Ulva lactuca and associated epiphytes sampled in five locations across the Strait. Variations in C and N isotopic signatures were observed in U. lactuca, pointing to a decrease in the availability of anthropogenic organic dissolved nitrogen along a north-south direction. Conversely, epiphytes did not show isotopic or elemental patterns across the Strait. These results suggest that preliminary stable isotope surveys in extended costal systems basing on U. lactuca can represent a valuable tool to focus meaningful targets and hypotheses for pollution studies in the Mediterranean region

  1. Preliminary calculation of αs from Green functions with dynamical quarks

    International Nuclear Information System (INIS)

    We present preliminary results on the computation of the QCD running coupling constant in the MOM-tilde scheme and Landau gauge with two flavours of dynamical Wilson quarks. Gluon momenta range up to about 7 GeV (β 5.6, 5.8 and 6.0) with a constant dynamical-quark mass. This range already allows to exhibit some evidence for a sizable 1/μ2 correction to the asymptotic behaviour, as in the quenched approximation, although a fit without power corrections is still possible with a reasonable χ2. Following the conclusions of our quenched study, we take into account 1/μ2 correction to the asymptotic behaviour. We find Λ Nf=2/MS=264(27)MeVx[a-1(5.6,0.1560)/2.19 GeV], which leads to αs(MZ) 0.113(3)(4). The latter result h as to be taken as a preliminary indication rather than a real prediction in view of the systematic errors still to be controlled. Still, being two sigmas below the experimental result makes it very encouraging. (author)

  2. Preliminary study on restarts for CSP algorithms

    OpenAIRE

    Baptista, Luís

    2010-01-01

    O uso de técnicas de restarts para resolver problemas de satisfação de restrições (CSPs), utilizando algoritmos de procura com retrocesso, é considerado pouco importante. Neste artigo propomos conduzir um estudo preliminar sobre o impacto da utilização de restarts nestes algoritmos. Mostramos que o conhecido problema da n-rainhas tem uma distribuição heavy-tail. Apresentamos evidências empíricas de que os restarts podem efectivamente melhorar o tempo necessário para encontrar a...

  3. Young Lives Preliminary Country Report: Peru.

    OpenAIRE

    Escobal, Javier; Lanata, Claudio; Madrid, Sofia; Penny, Mary; Saavedra, Jaime; Suárez,Pablo; Verastegui, Héctor; Villar, Eliana; Huttly, Sharon

    2003-01-01

    This report presents a brief literature review of childhood poverty in Peru, identifies key national audiences for the Young Lives study, explains the study methods used and presents provisional evidence, conclusions and policy implications. The Peruvian economy underwent a series of crises and external shocks in the 1980s and 1990s. The number of poor households rose rapidly from 43 per cent of the total in 1985-86 to 59 per cent in 1991. Despite reforms in the 1990s, Peru has one of the hig...

  4. Preliminary paleoseismic results from the Pastores fault and its role in the seismic hazard of the Acambay graben, Trans-Mexican Volcanic Belt, Mexico

    OpenAIRE

    Robert Max Langridge; Mira Persaud; Francisco Ramón Zúñiga; Gerardo de Jesús Aguirre-Díaz; Pilar Villamor; Pierre Lacan

    2013-01-01

    Shallow, crustal normal faulting earthquakes represent a significant seismic risk to the local towns and regional cities of central Mexico. Within the Acambay graben, the Pastores fault is a ca. 33 km long active, east-west striking, north-dipping normal fault. Two paleoseismic trenches were excavated at the Manto del Río site to estimate preliminary active fault and seismic hazard parameters. Both trenches showed evidence for at least two latest Pleistocene to Holocene paleo-earthquake ruptu...

  5. Revisit of I35W Bridge Collapse: A preliminary analysis at 2007 and conclusions today

    International Nuclear Information System (INIS)

    August 1st of 2007, 6:05PM, the interstate highway I35W Bridge in the City Minneapolis, Minnesota, collapsed suddenly. The 8 traffic-lane, 1000-foot-long deck of the 1907-foot-long bridge fell into Mississippi River within seconds, resulted in 13 fatalities and 145 injuries. This paper is based on a report of a preliminary analysis of this disaster, which was submitted to the related administrative agencies at the September of 2007. By comparing the results in that report with the materials' evidences of National Safety Transportation Safety Board (NTSB) official investigation and recent in-depth analyses, it seems that the issues addressed in this earlier analysis may still have certain significance for the safety assessment of those similarly-structured steel bridges today. A bridge's service life is 75 years or longer. According to a NTSB's document, there are more than hundreds this kind of bridges still on service.

  6. Potato contract farming and ‘privileged spaces’: preliminary insights from rural Maharashtra

    Directory of Open Access Journals (Sweden)

    Vicol, Mark

    2014-09-01

    Full Text Available The emergence of modern value chain schemes such as contract farming in rural India are exposing households to new forms of agricultural production. Evidently, the spread of such schemes in India will have spatial implications for rural development. This short communication offers preliminary insights of the contours of these spatial implications from a case study of potato contract farming in three villages in Maharashtra, India. It is proposed that studies that combine a local-scale livelihoods approach with global value chain analysis can strengthen understanding of agricultural change and rural development by grounding value chain analysis in the place-based everyday realities of rural households. Using this approach to adopt an evolutionary view of livelihoods and value chains will lead to a much deeper understanding of possible future development pathways for rural households under conditions of agricultural transformation.

  7. A Preliminary Study of the Effectiveness of Different Recitation Teaching Methods

    Science.gov (United States)

    Endorf, Robert J.; Koenig, Kathleen M.; Braun, Gregory A.

    2006-02-01

    We present preliminary results from a comparative study of student understanding for students who attended recitation classes which used different teaching methods. Student volunteers from our introductory calculus-based physics course attended a special recitation class that was taught using one of four different teaching methods. A total of 272 students were divided into approximately equal groups for each method. Students in each class were taught the same topic, "Changes in energy and momentum," from Tutorials in Introductory Physics. The different teaching methods varied in the amount of student and teacher engagement. Student understanding was evaluated through pretests and posttests given at the recitation class. Our results demonstrate the importance of the instructor's role in teaching recitation classes. The most effective teaching method was for students working in cooperative learning groups with the instructors questioning the groups using Socratic dialogue. These results provide guidance and evidence for the teaching methods which should be emphasized in training future teachers and faculty members.

  8. Prevention of post-rape psychopathology: preliminary findings of a controlled acute rape treatment study.

    Science.gov (United States)

    Resnick, H; Acierno, R; Holmes, M; Kilpatrick, D G; Jager, N

    1999-01-01

    Violent sexual assault such as rape typically results in extremely high levels of acute distress. The intensity of these acute psychological reactions may play a role in later recovery, with higher levels of immediate distress associated with poorer outcome. Unfortunately, post-rape forensic evidence collection procedures may serve to increase, rather than reduce initial distress, potentially exacerbating future psychopathology. To address these concerns, an acute time-frame hospital-based video intervention was developed to: (a) minimize anxiety during forensic rape exams, and (b) prevent post-rape posttraumatic stress disorder (PTSD), panic, and anxiety. Preliminary data indicated that (1) psychological distress at the time of the exam was strongly related to PTSD symptomatology 6 weeks post-rape, and (2) the video intervention successfully reduced distress during forensic exams. PMID:10504107

  9. Properties of the Lunar Interior: Preliminary Results from the GRAIL Mission

    Science.gov (United States)

    Williams, James G.; Konopliv, Alexander S.; Asmar, Sami W.; Lemoine, Frank G.; Melosh, H. Jay; Neumann, Gregory A.; Phillips, Roger J.; Smith, David E.; Solomon, Sean C.; Watkins, Michael M.; Wieczorek, Mark A.; Zuber, Maria T.; Andrews-Hanna, Jeffrey C.; Head, James W.; Kiefer, Walter S.; McGovern, Patrick J.; Nimmo, Francis; Taylor, G. Jeffrey; Weber, Renee C.; Boggs, D. H.; Goossens, Sander J.; Kruizinga, Gerhard L.; Mazarico, Erwan; Park, Ryan S.; Yuan, Dah-Ning

    2013-01-01

    The Gravity Recovery and Interior Laboratory (GRAIL) mission [1] has provided lunar gravity with unprecedented accuracy and resolution. GRAIL has produced a high-resolution map of the lunar gravity field [2,3] while also determining tidal response. We present the latest gravity field solution and its preliminary implications for the Moon's interior structure, exploring properties such as the mean density, moment of inertia of the solid Moon, and tidal potential Love number k(sub 2). Lunar structure includes a thin crust, a thick mantle layer, a fluid outer core, and a suspected solid inner core. An accurate Love number mainly improves knowledge of the fluid core and deep mantle. In the future, we will search for evidence of tidal dissipation and a solid inner core using GRAIL data.

  10. Effect of acceleration of the decay rate of 198Au: a preliminary report

    International Nuclear Information System (INIS)

    Experimental evidence obtained at the Los Alamos National Laboratory during 1980 suggests that the decay rate of 198Au may be influenced to a measurable extent by acceleration of the bulk material. In the experiments, a sample of 198Au was subjected to a sustained acceleration of approximately 196,000 g's, and its decay rate was compared with that of a control sample that remained at rest. The decay probability of the accelerated sample was observed to exceed that of the control sample by 7.48 standard deviations. This was the maximum value resulting from comparison of the accelerated sample data and the control sample data. Although not conclusive, these preliminary data are certainly suggestive that a direct coupling may exist between gravitation (acceleration) and nuclear processes

  11. Life span studies on mice exposed to heavy charged particles or photons: preliminary results

    International Nuclear Information System (INIS)

    This chapter summarizes the results currently available where dose-dependent mortality is compared among the single cohort that received fractionated doses of carbon ions and the first replicate that received single doses. At this time, 17% mortality has occurred in both groups and had enhanced life shortening been produced by fractionation of the carbon ion dose, somewhat higher mortality might be expected. Cautious interpretation of these preliminary results is necessary, but the mortality data available at this time provides no evidence for enhancement by dose fractionation with carbon ions. In sum, at this time, it appears the Q factor used for fission spectrum neutrons could be conservative if it were used for assessment of risk following exposure to 400 MeV carbon ions

  12. What counts as good evidence

    OpenAIRE

    Nutley, Sandra Margaret; Powell, Alison Elizabeth; Davies, Huw Talfryn Oakley

    2013-01-01

    Making better use of evidence is essential if public services are to deliver more for less. Central to this challenge is the need for a clearer understanding about standards of evidence that can be applied to the research informing social policy. This paper reviews the extent to which it is possible to reach a workable consensus on ways of identifying and labelling evidence. It does this by exploring the efforts made to date and the debates that have ensued. Throughout, the focus is on eviden...

  13. How to map the evidence

    DEFF Research Database (Denmark)

    Møller, Ann

    2012-01-01

    sponsored many projects in order to get new products onto the market. The lack of an overview and control has led to an abundance of evidence within certain areas of our specialty, whereas other areas are scarcely, or not at all, researched. One way of 'mapping' the evidence in order to find out what we...... know and what we do not know is the production of systematic reviews. Although systematic reviews are considered top of the evidence hierarchy, they are not flawless. The aim of this article is to explain the systematic review and point to some of the challenges in the development and use of systematic...

  14. First fungal genome sequence from Africa: A preliminary analysis

    Directory of Open Access Journals (Sweden)

    Rene Sutherland

    2012-01-01

    Full Text Available Some of the most significant breakthroughs in the biological sciences this century will emerge from the development of next generation sequencing technologies. The ease of availability of DNA sequence made possible through these new technologies has given researchers opportunities to study organisms in a manner that was not possible with Sanger sequencing. Scientists will, therefore, need to embrace genomics, as well as develop and nurture the human capacity to sequence genomes and utilise the ’tsunami‘ of data that emerge from genome sequencing. In response to these challenges, we sequenced the genome of Fusarium circinatum, a fungal pathogen of pine that causes pitch canker, a disease of great concern to the South African forestry industry. The sequencing work was conducted in South Africa, making F. circinatum the first eukaryotic organism for which the complete genome has been sequenced locally. Here we report on the process that was followed to sequence, assemble and perform a preliminary characterisation of the genome. Furthermore, details of the computer annotation and manual curation of this genome are presented. The F. circinatum genome was found to be nearly 44 million bases in size, which is similar to that of four other Fusarium genomes that have been sequenced elsewhere. The genome contains just over 15 000 open reading frames, which is less than that of the related species, Fusarium oxysporum, but more than that for Fusarium verticillioides. Amongst the various putative gene clusters identified in F. circinatum, those encoding the secondary metabolites fumosin and fusarin appeared to harbour evidence of gene translocation. It is anticipated that similar comparisons of other loci will provide insights into the genetic basis for pathogenicity of the pitch canker pathogen. Perhaps more importantly, this project has engaged a relatively large group of scientists

  15. Preliminary study of volcano monitoring using geochemical composition of lichen

    Science.gov (United States)

    KUAN, S.

    2012-12-01

    Taipei City, the capital of Taiwan, is bounded with Tatun Volcano Group (TVG), which is not active since 200 ka. However, some evidences indicate that the latest explosion of volcanic ash was dated to 5-6 ka as well as TVG is so close to metropolis. The monitoring on TVG is crucial for crisis management. For monitoring TVG, changes of geochemical signal in some volcanic gases and hot springs are currently assessed by monthly sampling. The geochemistry of volcanic gas and hot spring represents a short-term condition on sampling time and is highly controlled by temperature and precipitation on the surface. A long-term average geochemistry will be very helpful to be compared with the results of volcanic gas and hot spring. A bioindicator not only has the ability to store geochemical compositions in their tissues but also has a wide geographical distribution. It is very suitable in this kind of study and lichen is one of the best bioindicators mainly because lichens grow slowly and have a large-scale dependence upon the environment for their nutrition, In TVG, the high SO2 content in the atmosphere results in the absence of fruticose lichen. On the contrary, crustos lichen is the most common species in the study area. For the preliminary analysis, one fruticose, four foliose and four crustos lichens were collected around the major emission centers of volcanic gas. According to the results of ICP-MS analysis, the abundances of heavy metals are generally in the order of Zn, Fe, Mn, Cu, Cr, Pb, Cd, Ni, V, Co and U. Factor analysis (FA) demonstrates that most of the metals show very high loadings in the first factor. This means that the fractionation of metals among different lichen species is minor and the geochemical compositions of lichen are possibly controlled by the same source (atmosphere). The second factor of FA includes Mn, Sr and Ba, which share the same oxidation state of +2 in acidic environment. This factor can describe the variation of Mn, Sr and Ba in the

  16. A New Fusion Method for Conflicting Evidence

    Institute of Scientific and Technical Information of China (English)

    彭颖; 沈怀荣; 马永一

    2011-01-01

    A new conflicting evidence fusion method is proposed for the deficiency of Dempster' s rule which can not fuse the conflicting evidence. Evidence is divided into three categories: believable evidence, non-conflicting evidence and con- flicting evidence. The influences of these three categories of evidences on fusion results when discounted are analyzed respectively. On these bases, the evidence distance and the conjunctive conflict are utilized in sequence to recognize the be- lievable evidence and non-conflicting evidence. The discounting factors of these two categories of evidences are set to one, which keeps the evidences support the true hypothesis to the greatest degree, and makes the fusion results focus onto the true hypothesis. Examples of some missile fault diagnosis show that the new method can effectively fuse the conflicting evidences, and is suited to fuse the relievable evidences. The new method improves the reliability and rationality of fusion re- sults compared with traditional methods.

  17. "New" Persuasive Evidence for Evolution.

    Science.gov (United States)

    Max, Edward E.

    1998-01-01

    Discusses some new evidence for evolution that might be useful in persuading students who question the scientific basis for evolution. Draws on findings from the fields of molecular biology and genetics. (DDR)

  18. Gravitational Waves: The Evidence Mounts

    Science.gov (United States)

    Wick, Gerald L.

    1970-01-01

    Reviews the work of Weber and his colleagues in their attempts at detecting extraterrestial gravitational waves. Coincidence events recorded by special detectors provide the evidence for the existence of gravitational waves. Bibliography. (LC)

  19. Evidence accumulation for spatial reasoning

    Science.gov (United States)

    Matsuyama, T.; Hwang, V. S. S.; Davis, L. S.

    1984-01-01

    The evidence accumulation proces of an image understanding system is described enabling the system to perform top-down(goal-oriented) picture processing as well as bottom-up verification of consistent spatial relations among objects.

  20. Forensic Botany: Evidence and Analysis.

    Science.gov (United States)

    Coyle, H M

    2009-01-01

    Forensic botany is the use of plant evidence in matters of law. While plant fragments are often collected as trace evidence, they are only occasionally identified using microscopy and are still more rarely assessed using molecular biology techniques for individualization and sourcing of a sample. There are many different methods useful for DNA typing of plants; this review focuses on those techniques (DNA sequencing, STR, AFLP, RAPD) most relevant to the forensic science community and on those methods currently in practice. Plant evidence is commonly associated with homicides, with clandestine graves, as trace pollen on clothing, vehicles, or packaging, or in the transport of illicit drugs. DNA can be especially useful for the identification of minute quantity of samples, for differentiation of plants that lack distinguishing morphological features, and for generating a unique identifier for associative forensic evidence. PMID:26242238

  1. NASA 2010 Pharmacology Evidence Review

    Science.gov (United States)

    Steinberg, Susan

    2011-01-01

    In 2008, the Institute of Medicine reviewed NASA's Human Research Program Evidence in assessing the Pharmacology risk identified in NASA's Human Research Program Requirements Document (PRD). Since this review there was a major reorganization of the Pharmacology discipline within the HRP, as well as a re-evaluation of the Pharmacology evidence. This panel is being asked to review the latest version of the Pharmacology Evidence Report. Specifically, this panel will: (1) Appraise the descriptions of the human health-related risk in the HRP PRD. (2) Assess the relevance and comprehensiveness of the evidence in identifying potential threats to long-term space missions. (3) Assess the associated gaps in knowledge and identify additional areas for research as necessary.

  2. A preliminary study on titanium-clay interactions

    International Nuclear Information System (INIS)

    bentonite, Opalinus Clay, Illite du Puy) were characterized by XAS. Preliminary results can be summarized as: (1) Natural clay materials contain significant but variable amounts of Ti. The standard purification procedure for bentonites to remove accessories does not or only barely removes Ti. (2) The Ti in the natural clays materials Rokle bentonite, Opalinus Clay, Illite du Puy occurs as microcrystalline TiO2 (presumably as anatase). On the other hand, the Ti spectra in MX-80 suggest the presence of structural Ti in the smectite, but the evidence is not conclusive so far. (3) The exposure of purified MX-80 to titanium powder at room temperature within a period of five months did not lead to measurable additional Ti in the clay. This was even true for samples exposed to acidic or alkaline conditions where corrosion rates and solubility of Ti are known to be higher. Thereof, the following preliminary conclusions can be drawn: - The Ti content in natural bentonites is concentrated mainly in the so-called clay fraction. Ti occurs therein either as separate small TiO2 particles (Rokle, Opalinus Clay, Illite du Puy) or as structural Ti. As indicated by the study of Karnland et al. (2006), the properties of natural bentonites are not affected by the presence of Ti. In that study, the bulk properties (swelling pressure, hydraulic conductivity) were very similar for the different bentonites containing variable Ti content, ranging from 0.1 to 4.8 weight % TiO2 in the purified clay fractions. The transfer rates of Ti from the metallic source, even in reactive powder form, to the clay are very low and no enrichment above background concentrations after several months could be observed. In order to obtain measurable effects, both the corrosion process must be increased and the background concentration must be reduced. Tests with Ti-free clay material at increased temperature are still ongoing and will hopefully enable identification of reacted Ti species. (authors)

  3. Endovascular repair of aortic aneurysm: Preliminary results

    Directory of Open Access Journals (Sweden)

    Davidović Lazar

    2009-01-01

    Full Text Available Introduction. Endovascular aneurysm repair (EVAR has been introduced into clinical practice at the beginning of the 90's of the last century. Because of economic, political and social problems during the last 25 years, the introduction of this procedure in Serbia was not possible. Objective. The aim of this study was to present preliminary experiences and results of the Clinic for Vascular Surgery of the Serbian Clinical Centre in Belgrade in endovascular treatment of thoracic and abdominal aortic aneurysms. Methods. The procedure was performed in 33 patients (3 female and 30 male, aged from 42 to 83 years. Ten patients had a descending thoracic aorta aneurysm (three atherosclerotic, four traumatic - three chronic and one acute as a part of polytrauma, one dissected, two penetrated atherosclerotic ulcers, while 23 patients had the abdominal aortic aneurysm, one ruptured and two isolated iliac artery aneurysms. The indications for EVAR were isthmic aneurismal localisation, aged over 80 years and associated comorbidity (cardiac, pulmonary and cerebrovasular diseases, previous thoracotomy or multiple laparotomies associated with abdominal infection, idiopatic thrombocitopaenia. All of these patients had three or more risk factors. The diagnosis was established using duplex ultrasonography, angiography and MSCT. In the case of thoracic aneurysm, a Medtronic-Valiant® endovascular stent graft was implanted, while for the abdominal aortic aneurysm Medtronic-Talent® endovascular stent grafts with delivery systems were used. In three patients, following EVAR a surgical repair of the femoral artery aneurysm was performed, and in another three patients femoro-femoral cross over bypass followed implantation of aortouniiliac stent graft. Results. During procedure and follow-up period (mean 1.6 years, there were: one death, one conversion, one endoleak type 1, six patients with endoleak type 2 that disappeared during the follow-up period, one early graft

  4. Integrated Global Nuclear Materials Management Preliminary Concepts

    International Nuclear Information System (INIS)

    The world is at a turning point, moving away from the Cold War nuclear legacy towards a future global nuclear enterprise; and this presents a transformational challenge for nuclear materials management. Achieving safety and security during this transition is complicated by the diversified spectrum of threat 'players' that has greatly impacted nonproliferation, counterterrorism, and homeland security requirements. Rogue states and non-state actors no longer need self-contained national nuclear expertise, materials, and equipment due to availability from various sources in the nuclear market, thereby reducing the time, effort and cost for acquiring a nuclear weapon (i.e., manifestations of latency). The terrorist threat has changed the nature of military and national security requirements to protect these materials. An Integrated Global Nuclear Materials Management (IGNMM) approach would address the existing legacy nuclear materials and the evolution towards a nuclear energy future, while strengthening a regime to prevent nuclear weapon proliferation. In this paper, some preliminary concepts and studies of IGNMM will be presented. A systematic analysis of nuclear materials, activities, and controls can lead to a tractable, integrated global nuclear materials management architecture that can help remediate the past and manage the future. A systems approach is best suited to achieve multi-dimensional and interdependent solutions, including comprehensive, end-to-end capabilities; coordinated diverse elements for enhanced functionality with economy; and translation of goals/objectives or standards into locally optimized solutions. A risk-informed basis is excellent for evaluating system alternatives and performances, and it is especially appropriate for the security arena. Risk management strategies--such as defense-in-depth, diversity, and control quality--help to weave together various technologies and practices into a strong and robust security fabric. Effective

  5. Helminthiases in Montes Claros. Preliminary survey

    Directory of Open Access Journals (Sweden)

    Rina Girard Kaminsky

    1976-04-01

    Full Text Available A preliminary survey was conducted for the presence of helminths in the city of Montes Claros, M. G., Brazil. Three groups of persons were examined by the direct smear, Kato thick film and MIFC techniques; one group by direct smear and Kato only. General findings were: a high prevalence of hookworm, followed by ascariasis, S. mansoni, S. stercoralis and very light infections with T. trichiurá. E. vermicularis and H. nana were ranking parasites at an orphanage, with some hookworm and S. mansoni infections as well. At a pig slaughter house, the dominant parasites were hookworm and S. mansoni. Pig cysticercosis was an incidental finding worth mentioning for the health hazard it represents for humans as well as an economic loss. From the comparative results between the Kato and the MIF the former proved itself again as a more sensitive and reliable concentration method for helminth eggs, of low cost and easy performance.Um estudo preliminar sobre helmintos foi feito na cidade de Montes Claros, MG, Brasil. Três grupos de pessoas foram examinados pelos métodos direto, de Kato e do MIF e um grupo pelos métodos direto e Kato exclusivamente. Encontrou-se uma alta prevalência de necatorose, seguindo-se ascaríase, S. mansoni, S. stercoralis, e infecções leves pelo T. trichiura. E. vermicularis e H. nana foram osparasitos mais prevalentes num orfanato, com alguns casos de infecção pelo Necator e S. mansoni. Cisticercose dos suinos foi achado incidental e é importante ser mencionada devido ao perigo que representa no plano da Saúde Pública, bem como pela perda econômica que produz. Discutiu-se brevemente a importância do solo na transmissão dos helmintos num clima quente e seco. Da comparação dos métodos de Kato e MIF, o primeiro demonstrou ser o método mais sensível para ovos de helmintos, de baixo custo e fácil preparo.

  6. Evidence, Ethics & Social Policy Dilemmas

    OpenAIRE

    Steven I. Miller; L. Arthur Safer

    1993-01-01

    Within the philosophy of the social sciences, the relationship between evidence, ethics, and social policy is in need of further analysis. The present paper is an attempt to argue that while important social policies can, and perhaps ought to be, grounded in ethical theory, they are seldom articulated in this fashion due to the ambiguity surrounding the "evidence condition." Using a consequentialist-utilitarian framework, and a case study of a policy dilemma, the authors analyze the difficult...

  7. Texture Segmentation by Evidence Gathering

    OpenAIRE

    Waller, Ben; Nixon, Mark; Carter, John

    2011-01-01

    A new approach to texture segmentation is presented which uses Local Binary Pattern data to provide evidence from which pixels can be classified into texture classes. The proposed algorithm, which we contend to be the first use of evidence gathering in the field of texture classification, uses Generalised Hough Transform style R-tables as unique descriptors for each texture class and an accumulator is used to store votes for each texture class. Tests on the Brodatz database and Berkeley Segme...

  8. Preliminary studies on vigna unguiculata trypsin inhibitor

    International Nuclear Information System (INIS)

    Investigation on the presence of trypsin inhibitor in vigna unguiculata at three stages of ripeness, i.e. as young beans obtained from first harvest usually consumed as vegetable, seed from beans picked two weeks after the first harvest and seed from beans picked four weeks after the first harvest, has been carried out. The conclusion drawn from this experiment showed the existence of trypsin inhibitor at those stages of ripeness. It is found that the older the stage of ripeness the greater the specific activity of trypsin inhibitor. Evidently the heated extract loss its antitryptic activity progressively with increasing heatings periods. Extract heated on a water bath at a constant temperature of 78 deg C during 20, 40 and 60 minutes, loss its antitryptic activity of about 53, 78 and 96% respectively. (author)

  9. Preliminary results of thermal igniter experiments

    International Nuclear Information System (INIS)

    Thermal igniters (glow plugs), proposed by the Tennessee Valley Authority for intentional ignition of hydrogen in nuclear reactor containment, have been tested for functionability in mixtures of air, hydrogen, and steam. Test environments included 6% to 16% hydrogen concentrations in air, and 8%, 10%, and 12% hydrogen in mixtures with 30% and 40% steam functions. All were conducted in a 10.6 ft3 insulated pressure vessel. For all of these tests the glow plug successfully initiated combustion. Dry air/hydrogen tests exhibited a distinct tendency for complete combustion at hydrogen concentrations between 8% and 9%. Steam suppressed both peak pressures and completeness of combustion. No combustion could be initiated at or above a 50% steam fraction. Circulation of the mixture with a fan increased the completeness of combustion. The glow plug showed no evidence of performance degradation throughout the program

  10. Persuasive Evidence: Improving Customer Service through Evidence Based Librarianship

    Directory of Open Access Journals (Sweden)

    Wendy A. Abbott

    2006-03-01

    Full Text Available Objective - To demonstrate how evidence based practice has contributed to informaing decisions and resolving issues if concern in service delivery at Bond University Librray. Methods - This paper critically analyses three evidence based research projects conducted at Bond University Library. Each project combined a range of research methods including surveys, literature reviews and the analysis of internal performance data to find solutions to problems in library service delivery. The first research project investigated library opening hours and the feasability of twenty-four hour opening. Another project reseached questions about the management of a collection of feature films on DVD and video. The thrd project investigated issues surrounding the teaching of EndNote to undergarduate students. Results - Despite some deficiencies in the methodologies used, each evidence based research project had positive outcomes. One of the highlights asn an essential feature of the process at Bond University Library was the involvement of stakeholders. The ability to build consensus and agree action plans with stakeholders was an important outcome of that process. Conclusion - Drawing on the experience of these research projects, the paper illustrates the benefits of evidence based information practice to stimulate innovation and improve library services. Librarians, like most professionals, need to continue to develop the skills and a culture to effectively carry out evidence based practice.

  11. Evidence-based medicine and levels of evidence.

    Science.gov (United States)

    Wallace, David K

    2010-01-01

    Evidence-based medicine is the practice of making medical decisions based on evidence gained from applying the scientific method. Published studies are evaluated using three key questions: "Are the results valid?"; "What are the results?"; and "Can the results be applied to my patients?" The hierarchy of study methods for obtaining evidence is, in order from least to most useful: laboratory research, editorials, case reports and series, case-control studies, cohort studies, and randomized clinical trials. Retrospective case series can suffer from problems such as selection of a biased sample, mixing of treatment effects, and lack of control group. Randomized clinical trials (and meta-analyses of multiple trials) provide the highest level of evidence because randomization limits confounding and prevents bias of treatment assignment. In addition, randomized trials have standardization of interventions, prospective data collection, and masked outcome measures. Although every question cannot be addressed by a randomized clinical trial, the best available evidence should be sought and used to guide treatments. PMID:21061876

  12. Training Community Mental Health Therapists to Deliver a Package of Evidence-Based Practice Strategies for School-Age Children with Autism Spectrum Disorders: A Pilot Study

    Science.gov (United States)

    Brookman-Frazee, Lauren I.; Drahota, Amy; Stadnick, Nicole

    2012-01-01

    Research on moving evidence-based practice (EBP) intervention strategies to community service settings for children with autism spectrum disorders (ASD) is urgently needed. The current pilot study addresses this need by examining the feasibility, acceptability and preliminary outcomes of training therapists practicing in community mental health…

  13. 27 CFR 71.83 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Evidence. 71.83 Section 71... General § 71.83 Evidence. Any evidence which would be admissible under the rules of evidence governing... his case or defense by oral or documentary evidence, depositions, duly authenticated copies of...

  14. 31 CFR 8.64 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Evidence. 8.64 Section 8.64 Money and... AND FIREARMS Disciplinary Proceedings § 8.64 Evidence. (a) Rules of evidence. The rules of evidence... shall exclude evidence which is irrelevant, immaterial, or unduly repetitious. (b)...

  15. 42 CFR 423.1048 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 423.1048 Section 423.1048 Public Health....1048 Evidence. Evidence may be received at the hearing even though inadmissible under the rules of evidence applicable to court procedure. The ALJ rules on the admissibility of evidence....

  16. 42 CFR 498.61 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Evidence. 498.61 Section 498.61 Public Health... PROGRAM Hearings § 498.61 Evidence. Evidence may be received at the hearing even though inadmissible under the rules of evidence applicable to court procedure. The ALJ rules on the admissibility of evidence....

  17. From evidence-based to evidence-reflected practice

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    “Knowledge” is of the utmost significance for professional practice and learning. Today, though, the established knowledge base is changing in all areas of the labour market (Alvesson, 2004). Work and society are dominated by commitment to demands for high levels of demonstrable accountability......, cost-efficiency and measurable quality. Thus, today, evidence-based practice has become an expectation and fashion, often used to emphasize the grounding of practice in research based knowledge that provides measurable evidence for best practice. But at the same time, there is a growing distrust of the...

  18. Preliminary Phase Field Computational Model Development

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yulan [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hu, Shenyang Y. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Xu, Ke [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Suter, Jonathan D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McCloy, John S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Bradley R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-12-15

    experiments, special experimental methods were devised to create similar boundary conditions in the iron films. Preliminary MFM studies conducted on single and polycrystalline iron films with small sub-areas created with focused ion beam have correlated quite well qualitatively with phase-field simulations. However, phase-field model dimensions are still small relative to experiments thus far. We are in the process of increasing the size of the models and decreasing specimen size so both have identical dimensions. Ongoing research is focused on validation of the phase-field model. Validation is being accomplished through comparison with experimentally obtained MFM images (in progress), and planned measurements of major hysteresis loops and first order reversal curves. Extrapolation of simulation sizes to represent a more stochastic bulk-like system will require sampling of various simulations (i.e., with single non-magnetic defect, single magnetic defect, single grain boundary, single dislocation, etc.) with distributions of input parameters. These outputs can then be compared to laboratory magnetic measurements and ultimately to simulate magnetic Barkhausen noise signals.

  19. PRELIMINARY DESIGN BASIS EVENT ANALYSIS OF DOE SNF

    International Nuclear Information System (INIS)

    The purpose of this document is to perform a preliminary design basis event (DBE) analysis of the DOE Spent Nuclear Fuel (SNF) waste form. The objective of the analysis is to determine any preclosure safety impacts of the waste form on the Monitored Geologic Repository (MGR). The scope of this analysis is to determine the offsite dose consequences and associated frequencies of selected DBEs for systems handling disposable canisters that bound all surface and subsurface off-normal events, and to compare these results against regulatory limits. The results of this work are preliminary and are intended to be used to establish a set of preliminary MGR and waste form requirements, to identify mitigation or prevention features that may be required to meet regulatory limits, and to provide input to the Site Recommendation (SR) report. This document is prepared in accordance with the associated development plan (Civilian Radioactive Waste Management System Management and Operating Contractor [CRWMS M andO] 1999g)

  20. Preliminary characterization of abandoned septic tank systems. Volume 1

    International Nuclear Information System (INIS)

    This report documents the activities and findings of the Phase I Preliminary Characterization of Abandoned Septic Tank Systems. The purpose of the preliminary characterization activity was to investigate the Tiger Team abandoned septic systems (tanks and associated leachfields) for the purpose of identifying waste streams for closure at a later date. The work performed was not to fully characterize or remediate the sites. The abandoned systems potentially received wastes or effluent from buildings which could have discharged non-domestic, petroleum hydrocarbons, hazardous, radioactive and/or mixed wastes. A total of 20 sites were investigated for the preliminary characterization of identified abandoned septic systems. Of the 20 sites, 19 were located and characterized through samples collected from each tank(s) and, where applicable, associated leachfields. The abandoned septic tank systems are located in Areas 5, 12, 15, 25, and 26 on the Nevada Test Site

  1. Escalas de avaliação da leitura e da escrita: evidências preliminares de confiabilidade Reading and writing assessment scales: preliminary reliability evidences

    Directory of Open Access Journals (Sweden)

    Adriana de Souza Batista Kida

    2010-12-01

    Full Text Available TEMA: confiabilidade de Instrumentos de avaliação da leitura e escrita. Objetivo: investigar a confiabilidade de duas escalas elaboradas para a avaliação da leitura e escrita de crianças de 08 a 11:11 anos. MÉTODO: foram elaboradas duas escalas: de leitura, composta por doze itens de testes organizados em quatro campos de competências (conhecimento de letras e relação fono-grafêmica, decodificação de itens isolados, fluência de leitura de textos, compreensão de leitura, e de escrita com cinco itens organizados em três campos (escrita de letras e relação grafo-fonêmica, codificação de itens isolados, construção escrita. Selecionaram-se 100 escolares (64 meninas de rede pública com idade de 8 a 11:11 anos. Vinte (12 meninas participaram do estudo de aplicabilidade, que resultou na versão de estudo das escalas, posteriormente aplicadas aos demais 80 escolares (52 meninas. As respostas obtidas foram analisadas e computadas para atribuição dos escores de itens, escores por campo de competência (ECC e do escore bruto da escala (EBE. Os dados foram analisados estatisticamente, obtidos o coeficiente alpha de Cronbach e, complementarmente, as correlações entre os itens (coeficiente de correlação de Pearson. Adotou-se nível de significância de 0,05. RESULTADOS: Obtiveram-se α = 0,866 e α = 0,461 para as escalas de leitura e escrita, respectivamente. Correlações entre os itens foram observadas, variando de fracas a fortes e corroboraram os valores de alpha. CONCLUSÃO: a escala de leitura mostrou-se confiável, atingindo níveis admissíveis para instrumentos diagnósticos, enquanto que a escala de escrita não apresentou nível de confiabilidade admissível para mensurar o desempenho das crianças da amostra.BACKGROUND: reliability of Reading and Writing Assessment Instruments. AIM: to investigate the reliability of two scales created to evaluate both reading and writing of children with ages between 8:0 and 11:11 years. METHOD: two scales were created: a reading scale, composed of 12 testing items organized into four competency fields (letter knowledge and phonographemic relation, decoding of isolated items, reading fluency, reading comprehension, and a writing scale, with five items organized into three fields (letter writing and graphophonemic relation, codification of isolated items, writing construction. One hundred students (64 girls from Public Schools, with ages raging between 8:0 and 11:11 years, were selected. Twenty students (12 girls participated in the applicability study, resulting in the study version of the Scales. These scales were later applied to the remaining 80 students (52 girls. The obtained responses were assessed and computed for score assignment: item scores, competence field score (CFS and raw scale score (RSS. Data were submitted to statistical analysis: the Cronbach's alpha coefficient was calculated and correlations between items (Pearson's correlation coefficient were verified. A significance level of 0.05 was used. RESULTS: a = 0.866 and a = 0.461 were obtained for the Reading and Writing Scales, respectively. Correlations between the items were observed, ranging from weak to strong, and confirmed the alpha values. CONCLUSION: the Reading Scale was proven reliable, achieving acceptable levels for diagnostic instruments; the Writing Scale did not present an acceptable reliability level to measure the performance of the tested children.

  2. Preliminary evidence for a Hercynian age of the Versoyen complex, western Alps; Evidence preliminaire d'un age Hercynian pour le complexe du Versoyen, Alpes occidentales

    Energy Technology Data Exchange (ETDEWEB)

    Scharer, U. [Paris-7 Univ., Lab. de Geochronologie, UMR 7578, 75 (France); Cannic, S.; Lapierre, H. [Universite Joseph-Fourier, Lab. de Geologie des Chaines Alpines, Upres A5025, Institut Dolomieu, Grenoble I, 38 (France)

    2000-03-01

    To date the magmatic event that generated the Versoyen mafic complex, four fractions of zircon from a cross-cutting leuco-gabbro dike, has been analyzed by the U-Pb method, defining a regression line that intercepts the concordia curve at 309 {+-} 6 (2 {sigma}) Ma and 3 240 {+-} 34 Ma. These two ages can be interpreted to date, respectively, emplacement of the leuco-gabbro into the Versoyen complex, and the age of inherited Archean zircon cores, present in the newly formed crystals. The age of 309 Ma suggests that both Versoyen mafic magmatism and subsequent eclogite facies metamorphism belong to the Hercynian, and not the Alpine orogenic cycle. (authors)

  3. Preliminary environmental site assessments in New York City

    International Nuclear Information System (INIS)

    Preliminary Environmental Site Assessments are often performed prior to real estate transactions or refinancing. These assessments are typically performed for real estate buyers, sellers and lending institutions. Undertaking a Preliminary Environmental Site Assessment in New York City can often be quite complex and time-consuming. This is due, in part, to the age and density of buildings in the city as well as the myriad of regulatory agencies with jurisdiction over environmental issues. This paper will discuss how environmental assessments are performed with a special emphasis on building in New York City. In includes hazardous wastes management for Radon, PCB's and asbestos

  4. Preliminary orbital analysis of the LARES space experiment

    Science.gov (United States)

    Ciufolini, Ignazio; Paolozzi, Antonio; Pavlis, Erricos C.; Koenig, Rolf; Ries, John; Gurzadyan, Vahe; Matzner, Richard; Penrose, Roger; Sindoni, Giampiero; Paris, Claudio

    2015-07-01

    The LARES satellite was successfully launched in 2012 for tests of General Relativity and gravitational physics including the accurate measurement of frame-dragging. It is currently very well observed all over the world by the stations of the International Laser Ranging Service. Its preliminary orbital analyses show that LARES behaves as the best artificial massive test particle today available in the solar system, providing an optimal approximation to the time-like geodesic motion of General Relativity. Furthermore, on the basis of a test using almost three years of observations of LARES, we concluded that LARES, together with the LAGEOS and LAGEOS 2 satellites, provides excellent preliminary results for testing General Relativity.

  5. A preliminary bending fatigue spectrum for steel monostrand cables

    DEFF Research Database (Denmark)

    Winkler, Jan; Fischer, Gregor; Georgakis, Christos T.; Kotas, Agnieszka

    2011-01-01

    This paper presents the results of the experimental study on the bending fatigue resistance of high-strength steel monostrand cables. From the conducted fatigue tests in the high-stress, low-cycle region, a preliminary bending fatigue spectrum is derived for the estimation of monostrand cable...... service life expectancy. The presented preliminary bending fatigue spectrum of high-strength monostrands is currently unavailable in the published literature. The presented results provide relevant information on the bending mechanism and fatigue characteristics of monostrand steel cables in tension and...

  6. Advanced stellar compass - Onboard autonomous orbit determination, preliminary performance

    DEFF Research Database (Denmark)

    Betto, Maurizio; Jørgensen, John Leif; Jørgensen, Peter Siegbjørn;

    2004-01-01

    of this instrument, the authors have devised a method to determine the orbit of a spacecraft autonomously, onboard, and without a priori knowledge of any kind. The solution is robust and fast. This paper presents the preliminary performance obtained during the ground testing in August 2002 at the Mauna Kea...... Observatories. The main goals were: (1) to assess the robustness of the method in solving autonomously, onboard, the position lost-in-space problem; (2) to assess the preliminary accuracy achievable with a single planet and a single observation; (3) to verify the autonomous navigation (AutoNav) module could...

  7. Metal rich stars in omega Cen: preliminary FLAMES GTO results

    CERN Document Server

    Pancino, E

    2004-01-01

    I present preliminary results for a sample of ~700 red giants in omega Cen, observed during the Ital-FLAMES Consortium GTO time in May 2003, for the Bologna Project on omega Cen. Preliminary Fe and Ca abundances confirm previous results: while the metal-poor and intermediate populations show a normal halo alpha-enhancement of [alpha/Fe]=$+0.3, the most metal-rich stars show a significantly lower [alpha/Fe]=+0.1. If the metal-rich stars have evolved within the cluster in a process of self-enrichment, the only way to lower their alpha-enhancement would be SNe type Ia intervention.

  8. Design Preliminaries for Direct Drive under Water Wind Turbine Generator

    DEFF Research Database (Denmark)

    Leban, Krisztina Monika; Ritchie, Ewen; Argeseanu, Alin

    2012-01-01

    This paper focuses on the preliminary design process of a 20 MW electric generator. The application calls for an offshore, vertical axis, direct drive wind turbine. Arguments for selecting the type of electric machine for the application are presented and discussed. Comparison criteria for deciding...... on a type of machine are listed. Additional constraints emerging from the direct drive, vertical axis concepts are considered. General rules and a preliminary algorithm are discussed for the machine selected to be most suitable for the imposed conditions....

  9. Preliminary analysis of alternative fuel cycles for proliferation evaluation

    International Nuclear Information System (INIS)

    The ERDA Division of Nuclear Research and Applications proposed 67 nuclear fuel cycles for assessment as to their nonproliferation potential. The object of the assessment was to determine which fuel cycles pose inherently low risk for nuclear weapon proliferation while retaining the major benefits of nuclear energy. This report is a preliminary analysis of these fuel cycles to develop the fuel-recycle data that will complement reactor data, environmental data, and political considerations, which must be included in the overall evaluation. This report presents the preliminary evaluations from ANL, HEDL, ORNL, and SRL and is the basis for a continuing in-depth study

  10. Automated differential photometry of TAOS data: preliminary analysis

    CERN Document Server

    Ricci, D; Ayala, C; Ramón-Fox, F G; Michel, R; Navarro, S; Wang, S -Y; Zhang, Z -W; Lehner, M J; Nicastro, L; Reyes-Ruiz, M

    2014-01-01

    A preliminary data analysis of the stellar light curves obtained by the robotic telescopes of the TAOS project is presented. We selected a data run relative to one of the stellar fields observed by three of the four TAOS telescopes, and we investigate the common trend and the correlation between the light curves. We propose two ways to remove these trends and show the preliminary results. A project aimed at flagging interesting behaviors, such as stellar variability, and to set up an automated follow-up with the San Pedro M\\'artir Facilities is on the way.

  11. A robust optimization methodology for preliminary aircraft design

    Science.gov (United States)

    Prigent, S.; Maréchal, P.; Rondepierre, A.; Druot, T.; Belleville, M.

    2016-05-01

    This article focuses on a robust optimization of an aircraft preliminary design under operational constraints. According to engineers' know-how, the aircraft preliminary design problem can be modelled as an uncertain optimization problem whose objective (the cost or the fuel consumption) is almost affine, and whose constraints are convex. It is shown that this uncertain optimization problem can be approximated in a conservative manner by an uncertain linear optimization program, which enables the use of the techniques of robust linear programming of Ben-Tal, El Ghaoui, and Nemirovski [Robust Optimization, Princeton University Press, 2009]. This methodology is then applied to two real cases of aircraft design and numerical results are presented.

  12. Preliminary design package for prototype solar heating and cooling systems

    Science.gov (United States)

    1978-01-01

    A summary is given of the preliminary analysis and design activity on solar heating and cooling systems. The analysis was made without site specific data other than weather; therefore, the results indicate performance expected under these special conditions. Major items include a market analysis, design approaches, trade studies and other special data required to evaluate the preliminary analysis and design. The program calls for the development and delivery of eight prototype solar heating and cooling systems for installation and operational test. Two heating and six heating and cooling units will be delivered for Single Family Residences, Multiple-family Residences and commercial applications.

  13. Hydrogen-burn survival: preliminary thermal model and test results

    Energy Technology Data Exchange (ETDEWEB)

    McCulloch, W.H.; Ratzel, A.C.; Kempka, S.N.; Furgal, D.T.; Aragon, J.J.

    1982-08-01

    This report documents preliminary Hydrogen Burn Survival (HBS) Program experimental and analytical work conducted through February 1982. The effects of hydrogen deflagrations on safety-related equipment in nuclear power plant containment buildings are considered. Preliminary results from hydrogen deflagration experiments in the Sandia Variable Geometry Experimental System (VGES) are presented and analytical predictions for these tests are compared and discussed. Analytical estimates of component thermal responses to hydrogen deflagrations in the upper and lower compartments of an ice condenser, pressurized water reactor are also presented.

  14. Hydrogen-burn survival: preliminary thermal model and test results

    International Nuclear Information System (INIS)

    This report documents preliminary Hydrogen Burn Survival (HBS) Program experimental and analytical work conducted through February 1982. The effects of hydrogen deflagrations on safety-related equipment in nuclear power plant containment buildings are considered. Preliminary results from hydrogen deflagration experiments in the Sandia Variable Geometry Experimental System (VGES) are presented and analytical predictions for these tests are compared and discussed. Analytical estimates of component thermal responses to hydrogen deflagrations in the upper and lower compartments of an ice condenser, pressurized water reactor are also presented

  15. Energy Efficient Engine: Control system preliminary definition report

    Science.gov (United States)

    Howe, David C.

    1986-01-01

    The object of the Control Preliminary Definition Program was to define a preliminary control system concept as a part of the Energy Efficient Engine program. The program was limited to a conceptual definition of a full authority digital electronic control system. System requirements were determined and a control system was conceptually defined to these requirements. Areas requiring technological development were identified and a plan was established for implementing the identified technological features, including a control technology demonstration. A significant element of this program was a study of the potential benefits of closed-loop active clearance control, along with laboratory tests of candidate clearance sensor elements for a closed loop system.

  16. Preliminary Validation and Verification Plan for CAREM Reactor Protection System

    International Nuclear Information System (INIS)

    The purpose of this paper, is to present a preliminary validation and verification plan for a particular architecture proposed for the CAREM reactor protection system with software modules (computer based system).These software modules can be either own design systems or systems based in commercial modules such as programmable logic controllers (PLC) redundant of last generation.During this study, it was seen that this plan can also be used as a validation and verification plan of commercial products (COTS, commercial off the shelf) and/or smart transmitters.The software life cycle proposed and its features are presented, and also the advantages of the preliminary validation and verification plan

  17. Evidence in the learning organization

    Directory of Open Access Journals (Sweden)

    Umscheid Craig A

    2009-03-01

    Full Text Available Abstract Background Organizational leaders in business and medicine have been experiencing a similar dilemma: how to ensure that their organizational members are adopting work innovations in a timely fashion. Organizational leaders in healthcare have attempted to resolve this dilemma by offering specific solutions, such as evidence-based medicine (EBM, but organizations are still not systematically adopting evidence-based practice innovations as rapidly as expected by policy-makers (the knowing-doing gap problem. Some business leaders have adopted a systems-based perspective, called the learning organization (LO, to address a similar dilemma. Three years ago, the Society of General Internal Medicine's Evidence-based Medicine Task Force began an inquiry to integrate the EBM and LO concepts into one model to address the knowing-doing gap problem. Methods During the model development process, the authors searched several databases for relevant LO frameworks and their related concepts by using a broad search strategy. To identify the key LO frameworks and consolidate them into one model, the authors used consensus-based decision-making and a narrative thematic synthesis guided by several qualitative criteria. The authors subjected the model to external, independent review and improved upon its design with this feedback. Results The authors found seven LO frameworks particularly relevant to evidence-based practice innovations in organizations. The authors describe their interpretations of these frameworks for healthcare organizations, the process they used to integrate the LO frameworks with EBM principles, and the resulting Evidence in the Learning Organization (ELO model. They also provide a health organization scenario to illustrate ELO concepts in application. Conclusion The authors intend, by sharing the LO frameworks and the ELO model, to help organizations identify their capacities to learn and share knowledge about evidence-based practice

  18. Integrating evidence into practice: use of McKenzie-based treatment for mechanical low back pain

    Directory of Open Access Journals (Sweden)

    Clarke S

    2011-11-01

    Full Text Available Angela Dunsford1, Saravana Kumar1,2, Sarah Clarke1 1International Centre for Allied Health Evidence, 2School of Health Sciences, University of South Australia, Adelaide, South Australia, Australia Abstract: Low back pain (LBP is a major health issue with significant socioeconomic implications in most Western countries. Many forms of treatment have been proposed and investigated in the past, with exercise being a commonly prescribed intervention. Within allied health, in particular physiotherapy, there has been a growing movement that recognizes the role of the McKenzie method in treating LBP. Within the McKenzie framework, directional preference (DP exercises are one such intervention, with preliminary data demonstrating its effectiveness in the management of LBP. In this paper, we aim to integrate the evidence from current research, identified using a systematic review, and utilize a practical real-life case scenario to outline how evidence from the literature can be implemented in clinical practice. The findings from the systematic review indicate that DP exercises may have positive effects in the management of LBP. While the body of evidence to support this is limited (only four studies and therefore modest at best, it does provide some emerging evidence to support the use of DP exercises in clinical practice. Despite this, gaps also persist in the literature on DP exercises, and this relates to the exercise parameters and the compliance rates. Recognizing this dichotomy (modest evidence in some areas and evidence gaps in other areas, which is likely to confront health practitioners, using a practical approach with a real-life clinical scenario, we outline how the evidence from the systematic review can be implemented in clinical practice. This approach builds on the philosophy of evidence-based practice of integrating research evidence with clinical expertise and patient values. Keywords: low back pain, McKenzie method, directional

  19. The Notion of Evidence in Evidence-Based Practice by the Nursing Philosophy Working Group.

    Science.gov (United States)

    Romyn, Donna M.; Allen, Marion N.; Boschma, Geertje; Duncan, Susan M.; Edgecombe, Nancy; Jensen, Louise A.; Ross-Kerr, Janet C.; Marck, Patricia; Salsali, Mahvash; Tourangeau, Ann E.; Warnock, Fay

    2003-01-01

    Addresses these questions: To what end is evidence sought? What is the nature of evidence? What kinds of evidence are valued by the nursing profession? and What kinds of evidence should underlie clinical decision making? (Contains 28 references.) (SK)

  20. Scientific Evidence for Hydrostatic Shock

    CERN Document Server

    Courtney, Michael

    2008-01-01

    This paper reviews the scientific support for a ballistic pressure wave radiating outward from a penetrating projectile and causing injury and incapacitation. This phenomenon is known colloquially as "hydrostatic shock." The idea apparently originates with Col. Frank Chamberlin, a World War II trauma surgeon and wound ballistics researcher. The paper reviews claims that hydrostatic shock is a myth and considers supporting evidence through parallels with blast, describing the physics of the pressure wave, evidence for remote cerebral effects, and remote effects in the spine and other internal organs. Finally, the review considers the levels of energy transfer required for the phenomenon to be readily observed.

  1. Evidence on global medical travel.

    Science.gov (United States)

    Ruggeri, Kai; Záliš, Ladislav; Meurice, Christopher R; Hilton, Ian; Ly, Terry-Lisa; Zupan, Zorana; Hinrichs, Saba

    2015-11-01

    The potential benefits of travelling across national borders to obtain medical treatment include improved care, decreased costs and reduced waiting times. However, medical travel involves additional risks, compared to obtaining treatment domestically. We review the publicly-available evidence on medical travel. We suggest that medical travel needs to be understood in terms of its potential risks and benefits so that it can be evaluated against alternatives by patients who are seeking care. We propose three domains -quality standards, informed decision-making, economic and legal protection - in which better evidence could support the development of medical travel policies. PMID:26549906

  2. Evidence-based playground design

    DEFF Research Database (Denmark)

    Refshauge, Anne Dahl; Stigsdotter, Ulrika K.; Lamm, Bettina;

    2015-01-01

    , best practice, and the theories of Affordances and Behaviour Settings. A post-occupancy evaluation was carried out through a questionnaire survey and observation studies, which revealed that a majority of the potential evidence-based affordances were actualised, and that the application of the theories...

  3. Evidence-Based IT Development

    DEFF Research Database (Denmark)

    Simonsen, Jesper; Hertzum, Morten

    2005-01-01

    Evidence-based IT development aims at developing a new commercial contract model for IT projects where the cus-tomers payment is dependent on measurable effects of using the vendors system. The idea is to establish a strategic part-nership in which customer and IT vendor share the responsi-bility...

  4. Learned Helplessness: Theory and Evidence

    Science.gov (United States)

    Maier, Steven F.; Seligman, Martin E. P.

    1976-01-01

    Authors believes that three phenomena are all instances of "learned helplessness," instances in which an organism has learned that outcomes are uncontrollable by his responses and is seriously debilitated by this knowledge. This article explores the evidence for the phenomena of learned helplessness, and discussed a variety of theoretical…

  5. Multiple sclerosis: evidence and controversies

    OpenAIRE

    Ángela María Gutiérrez-Álvarez

    2006-01-01

    Introduction: Multiple sclerosis is a chronicrecurrent inflammatory disorder of the centralnervous system. The pharmacological treatmentof multiple sclerosis has been evaluated withmultiple controlled clinical trials that allow theclinician to count with evidence based informationto decide the more indicated treatmentfor each patient.Methodology: A review of the scientific literaturewas conducted to clarify controversialissues in a clinical relevant topic.Development: The diagnostic criteria ...

  6. Elderly Return Migration from Britain to Ireland - A Preliminary Study

    OpenAIRE

    Department of Health

    1996-01-01

    The National Council for the Elderly commissioned the Institute of Irish Studies at the University of Liverpool, in 1994, to undertake research and prepare a preliminary report for the Council, exploring the recent scale of, and background to, return migration to the Republic of Ireland amongst elderly Irish-born people living in Britain Download the Report here

  7. Influence of preliminary annealing on sound velocity in strained polymers

    International Nuclear Information System (INIS)

    Present article is devoted to influence of preliminary annealing on sound velocity in strained polymers. The dependence of sound velocity on loading duration in natural silk at 77 Mpa and different annealing duration was studied. The structural changes occurring in strained polymers at thermal treatment were considered.

  8. Yucca Mountain transportation routes: Preliminary characterization and risk analysis

    International Nuclear Information System (INIS)

    This report presents appendices related to the preliminary assessment and risk analysis for high-level radioactive waste transportation routes to the proposed Yucca Mountain Project repository. Information includes data on population density, traffic volume, ecologically sensitive areas, and accident history

  9. Strategies for Nurturing Journalism Students: A Preliminary Report.

    Science.gov (United States)

    1990

    This preliminary report discusses a survey of journalism schools conducted in February 1990 by the Association for Education in Journalism and Mass Communication (ASJMC) seeking data on liaisons between college journalism schools and high schools as well as ideas for ASJMC members seeking new ways to reach prospective journalists among high school…

  10. Preliminary study to AP mine neutralisation by EFP impact

    NARCIS (Netherlands)

    Meulman, J.H.

    2004-01-01

    A preliminary study has been conducted into the response of anti-personnel mines at the impact of an Explosively Formed Projectile (EFP). The objective was to obtain a low order reaction (preferably a deflagration) to minimise collateral damage. Further the method should be capable to neutralise min

  11. Connecticut Transit (CTTRANSIT) Fuel Cell Transit Bus: Preliminary Evaluation Results

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2008-10-01

    This report provides preliminary results from a National Renewable Energy Laboratory evaluation of a protoptye fuel cell transit bus operating at Connecticut Transit in Hartford. Included are descriptions of the planned fuel cell bus demonstration and equipment; early results and agency experience are also provided.

  12. PRELIMINARY STUDY OF FLOWERING PLANT DIVERSITY OF NIMAR REGION

    OpenAIRE

    Jeetendra sainkhediya; Sudip Ray

    2012-01-01

    An extensive and intensive plant survey of Khandwa and Khargone district of Nimar region was carried out. Preliminary study of Nimar region shows rich plant diversity in respect to 72 families and 222 genera. Present study observes 17 threatened plants of which Oroxylum indicum L., Gloriosa superba L., Ceropegia hirsuta wt & Arm., Viscum articulatum Auct., Oryza rufipogon Griff., are depleting at alarming rate.

  13. The 2dF Galaxy Redshift Survey: Preliminary Results

    OpenAIRE

    Maddox, S.

    1997-01-01

    Spectroscopic observations for a new survey of 250 000 galaxy redshifts are underway, using the 2dF instrument at the AAT. The input galaxy catalogue and commissioning data are described. The first result from the preliminary data is a new estimate of the galaxy luminosity function at =0.1.

  14. Preliminary results of neutron production in Sahand plasma focus device

    International Nuclear Information System (INIS)

    We report in this paper the preliminary results of neutron generation during fusion reaction in deuterium in the Sahand Filipov type plasma focus, recently installed and put in operation at Tabriz University. The special calibration procedure for neutron detection system, using activation method is described

  15. Preliminary System Design of the SWRL Financial System.

    Science.gov (United States)

    Ikeda, Masumi

    The preliminary system design of the computer-based Southwest Regional Laboratory's (SWRL) Financial System is outlined. The system is designed to produce various management and accounting reports needed to maintain control of SWRL operational and financial activities. Included in the document are descriptions of the various types of system…

  16. Preliminary Design Study of a Hybrid Airship for Flight Research

    Science.gov (United States)

    Browning, R. G. E.

    1981-01-01

    The feasibility of using components from four small helicopters and an airship envelope as the basis for a quad-rotor research aircraft was studied. Preliminary investigations included a review of candidate hardware and various combinations of rotor craft/airship configurations. A selected vehicle was analyzed to assess its structural and performance characteristics.

  17. Oxygenates in automotive fuels. Consequence analysis - preliminary study

    International Nuclear Information System (INIS)

    Oxygenates is used in gasoline due to several reasons. They are added as high-octane components in unleaded gasoline and as agents to reduce the emission of harmful substances. Oxygenates produced from biomass might constitute a coming market for alternative fuels. This preliminary study describes the prerequisites and consequences of such an oxygenate utilization. 39 refs, 9 figs, 5 tabs

  18. On the quadratic stability of switched interval systems: Preliminary results

    OpenAIRE

    Zeheb, Ezra; Mason, Oliver; SOLMAZ, Selim; Shorten, Robert

    2005-01-01

    In this paper we present some preliminary results on the quadratic stability of switched systems with uncertain parameters. We show that the quadratic stability of a class of switched uncertain systems may be readily verified using simple algebraic conditions. Examples are presented to demonstrate the efficacy of our techniques.

  19. Modular endoprosthesis for mandibular reconstruction: a preliminary animal study.

    NARCIS (Netherlands)

    Lee, S.; Goh, B.T.; Tideman, H.; Stoelinga, P.J.W.

    2008-01-01

    The use of a mandibular modular endoprosthesis after segmental resection of part of the body of the mandible was studied. This preliminary study was carried out on four pigs and four monkeys. The devices were made of a titanium alloy and were cemented in the prepared medullary spaces with polymethyl

  20. Preliminary studies on the holding of live mussels after harvest

    OpenAIRE

    Yap, W.G.; Orano, C.F.

    1980-01-01

    Green mussel (Perna viridis) were harvested to study the applicability of chilling to keep the mussels alive for a longer period of time and to review existing methods of packaging and transport. Data obtained from preliminary studies indicated the effectiveness of keeping mussels alive as long as 4 days with minimal mortality rates.

  1. Preliminary test experiment for electron beam injection to JSR

    International Nuclear Information System (INIS)

    A preliminary test experiment has been carried out to investigate the property of electron beam from the JAERI linac which will be used as an injector for the JSR(JAERI Storage Ring). The electron beam was obtained within the energy resolution of 1.55 % and the peak current of 38 mA at 150 MeV. (author)

  2. Isotope separation by electrolytic amalgamation of lithium: preliminary studies

    International Nuclear Information System (INIS)

    Preliminary experiments on electrolytic amalgamation of lithium aqueous solutions were performed in order to obtain data for the design of an electrolytic cell with a moving mercury cathode. Among the two electrolytes analyzed Li OH gave best yield than Li Cl. Current concentration, current density and lithium amalgam concentration were determined. (author)

  3. Preliminary analysis of patent trends for magnetic fusion technology

    International Nuclear Information System (INIS)

    This study presents a preliminary analysis of development trends in magnetic fusion technology based on data from US patents. The research is limited to identification and description of general patent activity and ownership characteristics for 373 patents. The results suggest that more detailed studies of fusion patents could provide useful R and D planning information

  4. Preliminary analysis of patent trends for magnetic fusion technology

    Energy Technology Data Exchange (ETDEWEB)

    Levine, L.O.; Ashton, W.B.; Campbell, R.S.

    1984-02-01

    This study presents a preliminary analysis of development trends in magnetic fusion technology based on data from US patents. The research is limited to identification and description of general patent activity and ownership characteristics for 373 patents. The results suggest that more detailed studies of fusion patents could provide useful R and D planning information.

  5. Structural investigations of biogenic iron oxide samples. Preliminary results

    International Nuclear Information System (INIS)

    Some preliminary results on morphology and structure of iron oxide particles formed inside Klebsiella oxytoca bacteria are presented. In particular, by means of optical microscopy, scanning electron microscopy and small-angle X-ray scattering the effect of the bacteria age (the duration of growth) on the nanoparticles properties is studied

  6. PTSD and Impaired Eye Expression Recognition: A Preliminary Study

    Science.gov (United States)

    Schmidt, Jakob Zeuthen; Zachariae, Robert

    2009-01-01

    This preliminary study examined whether posttraumatic stress disorder (PTSD) was related to difficulties in identifying the mental states of others in a group of refugees. Sixteen Bosnian refugees, referred to treatment in an outpatient treatment center for survivors of torture and war-related trauma in Denmark (CETT), were compared to 16 non-PTSD…

  7. [Evaluation of preliminary grades and credits in nurse training programs].

    Science.gov (United States)

    Darmann-Finck, Ingrid; Duveneck, Nicole

    2016-01-01

    In the federal state of Bremen preliminary grades were included to the extent of 25 % in written, oral and practical final grades during the time period 2009-2014. The evaluation focuses on the effects of preliminary grades on the scale of final grades and the performance of learners as well as on the assessment of the appropriateness of final grades. A mixed-methods design was employed that consisted of a quasi-experimental study comprising of surveys of students and teachers of comparative and model courses as well as a qualitative study using group discussions. The results confirm that preliminary grades lead to a minimal improvement of the final grades of some exclusively low-achieving students. The assessment of appropriateness hardly changed. From both learners' and teachers' point of view there is still great dissatisfaction concerning the practical final grades. With regard to learning habits an increased willingness to learn new skills on the one hand and a partly increased performance pressure on the other hand were demonstrated. On the basis of these research results, the authors recommend the regular introduction of preliminary marks into the nursing training. PMID:27480188

  8. Automatic encoding into SNOMED III: a preliminary investigation.

    OpenAIRE

    Sager, N.; Lyman, M.; Nhàn, N. T.; Tick, L J

    1994-01-01

    The Linguistic String Project (LSP) medical language processing (MLP) system converts narrative clinical reports into database tables of patient data. A procedure for mapping the output of the LSP MLP system into SNOMED III codes was developed. Preliminary results and further requirements are discussed.

  9. 40 CFR 154.31 - Notices of Preliminary Determination.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Notices of Preliminary Determination. 154.31 Section 154.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE..., social, and environmental costs and benefits of the use of the product, and a discussion of reasons...

  10. Using On-Line Bulletin Boards to Gather Preliminary Information

    Science.gov (United States)

    Kelley, Kathleen; Govindasamy, Ramu; Hyde, Jeffrey

    2012-01-01

    Internet bulletin-board sessions can be used to collect preliminary, qualitative data. This method allows Extension personnel to gather responses from stakeholders about potential programming, consumer needs and desires, and preference for program delivery method without assembling participants in one location. Several other advantages exist,…

  11. The Fisher Effect in the Spanish Case: A Preliminary Study

    OpenAIRE

    Francisco Jareño; Marta Tolentino

    2012-01-01

    We revise previous literature about Fisher Effect, in order to check if the majority of nominal interest rates movements are caused by inflation rate fluctuations, remaining constant the real interest rate. Finally, we analyse the Fisher Effect in the Spanish case with a preliminary analysis in order to validate future studies.

  12. PRELIMINARY ECONOMIC ANALYSIS OF A LIME SPRAY DRYER FGD SYSTEM

    Science.gov (United States)

    The report gives results of a preliminary economic analysis of two flue gas desulfurization (FGD) processes (one dry and one wet) for a new 500-MW power plant burning Western coal having 0.7% sulfur, 9.7% ash, and a heating value of 9700 Btu/lb and meeting current new source perf...

  13. Exploring Linguistic Features for Web Spam Detection: A Preliminary Study

    OpenAIRE

    SYDOW Marcin; WEISS Dawid

    2008-01-01

    We study the usability of linguistic features in theWeb spam classification task. The features were computed on two Web spam corpora: Webspam-Uk2006 and Webspam-Uk2007, we make them publicly available for other researchers. Preliminary analysis seems to indicate that certain linguistic features may be useful for the spam-detection task when combined with features studied elsewhere.

  14. Preliminary fabrication studies of alternative LMFBR carbide fuels

    International Nuclear Information System (INIS)

    Preliminary fabrication studies were made of various compositions of thorium-uranium carbide and thorium-plutonium carbide fuel pellets that were prepared using the carbothermic reduction process. Temperatures of 1750 and 20000C were used during the reduction cycle. Sintering temperatures of 1800 and 20000C were used to prepare fuel pellets of low (87%) and high (> 94%) theoretical densities

  15. Radon concentrations in Norwegian kindergartens: survey planning and preliminary results

    International Nuclear Information System (INIS)

    An extensive radon survey in Norwegian kindergartens and schools was started in early 1997; so far 2481 kindergartens were examined. Preliminary results of the first phase of the survey are presented in tabular and graphic form including, among others, the dependence of average radon concentration on the construction year of the kindergartens and on the age of the buildings. (A.K.)

  16. Preliminary Test for Nonlinear Input Output Relations in SISO Systems

    DEFF Research Database (Denmark)

    Knudsen, Torben

    2000-01-01

    This paper discusses and develops preliminary statistical tests for detecting nonlinearities in the deterministic part of SISO systems with noise. The most referenced method is unreliable for common noise processes as e.g.\\ colored. Therefore two new methods based on superposition and sinus input...

  17. 76 FR 16409 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2011-03-23

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing Lock+ Hydro Friends Fund XXXIV... random drawing to determine the filing priority of the applicants identified in this notice. The...\\ The priority established by this drawing will be used to determine which applicant, among those...

  18. 76 FR 4893 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2011-01-27

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing January 20, 2011. Lock Hydro..., at 10 a.m. (eastern time), the Secretary of the Commission, or her designee, will, by random drawing, determine the filing priority for the three applicants identified in this notice. The drawing is open to...

  19. 76 FR 16406 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2011-03-23

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing ] Lock+ Hydro Friends Fund... random drawing to determine the filing priority of the applicants identified in this notice. The...\\ The priority established by this drawing will be used to determine which applicant, among those...

  20. 76 FR 16407 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2011-03-23

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing Lock+ Hydro Friends Fund XLVI... random drawing to determine the filing priority of the applicants identified in this notice. The...\\ The priority established by this drawing will be used to determine which applicant, among those...

  1. 76 FR 16408 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2011-03-23

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing Lock+ Hydro Friends Fund XXXVII... Secretary of the Commission, or her designee, will conduct a random drawing to determine the filing priority... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing...

  2. 77 FR 24197 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-04-23

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing Mississippi 8 Hydro, LLC... drawing to determine the filing priority of the applicants identified in this notice. The Commission will... priority established by this drawing will be used to determine which applicant, among those with...

  3. 75 FR 32459 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2010-06-08

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing May 28, 2010. In the matter of... Commission, or her designee, will, by random drawing, determine the filing priority for the two applicants identified in this notice. The drawing is open to the public and will be held in room 2C, the...

  4. 77 FR 10739 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-23

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing Project No. FFP Project 91, LLC... Secretary of the Commission, or her designee, will conduct a random drawing to determine the filing priority... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing...

  5. 77 FR 9915 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-21

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing Lock+ Hydro Friends Fund XLI... conduct a random drawing to determine the filing priority of the applicants identified in this notice. The...\\ The priority established by this drawing will be used to determine which applicant, among those...

  6. 76 FR 4894 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2011-01-27

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing January 20, 2011. Lock Hydro... Commission, or her designee, will, by random drawing, determine the filing priority for the two applicants identified in this notice. The drawing is open to the public and will be held in room 2C, the...

  7. 76 FR 15972 - Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2011-03-22

    ... Energy Regulatory Commission Notice Announcing Preliminary Permit Drawing Project No. Lock+ Hydro Friends... designee, will conduct a random drawing to determine the filing priority of the applicants identified in... of its regulations.\\2\\ The priority established by this drawing will be used to determine...

  8. Preliminary results of the surveillance extension program of NPP Paks

    International Nuclear Information System (INIS)

    The paper describes the preliminary stage of the surveillance extension programme at NPP Paks. To prepare the surveillance extension programme 5 set of specimens including 6 different forging and weldment have been irradiated and tested. The obtained results are used in the final design of the extended surveillance programme of NPP Paks. (author). 3 refs, 6 figs, 1 tab

  9. Technology User Groups and Early Childhood Education: A Preliminary Study

    Science.gov (United States)

    Parette, Howard P.; Hourcade, Jack J.; Blum, Craig; Watts, Emily H.; Stoner, Julia B.; Wojcik, Brian W.; Chrismore, Shannon B.

    2013-01-01

    This article presents a preliminary examination of the potential of Technology User Groups as a professional development venue for early childhood education professionals in developing operational and functional competence in using hardware and software components of a Technology toolkit. Technology user groups are composed of varying numbers of…

  10. Preliminary design report for the prototypical fuel rod consolidation system

    International Nuclear Information System (INIS)

    This report documents NUTECH's preliminary design of a dry, spent fuel rod consolidation system. This preliminary design is the result of Phase I of a planned four phase project. The present report on this project provides a considerable amount of detail for a preliminary design effort. The design and all of its details are described in this Preliminary Design Report (PDR). The NUTECH dry rod consolidation system described herein is remotely operated. It provides for automatic operation, but with operator hold points between key steps in the process. The operator has the ability to switch to a manual operation mode at any point in the process. The system is directed by the operator using an executive computer which controls and coordinates the operation of the in-cell equipment. The operator monitors the process using an in-cell closed circuit television (CCTV) system with audio output and equipment status displays on the computer monitor. The in-cell mechanical equipment consists of the following: (1) two overhead cranes with manipulators; (2) a multi-degree of freedom fuel handling table and its clamping equipment; (3) a fuel assembly end fitting removal station and its tools; (4) a consolidator (which pulls rods, assembles the consolidated bundle and loads the canister); (5) a canister end cap welder and weld inspection system; (6) decontamination systems; and (7) the CCTV and microphone systems

  11. PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND THIN LAYER CHROMATOGRAPHY OF RHEUM EMODI

    OpenAIRE

    Mir Ashfaq Ahmad; K. W. Shah; Showkat Ahmad Wani

    2012-01-01

    Preliminary phytochemical investigation of aqueous and methanolic rhizome extracts of Rheum emodi followed by their TLC profiling were carried out. Phytochemical analysis reveals the presence of diverse groups of phytoconstituents in two different extracts (aqueous and methanolic rhizome extracts). Chemical constituents also show different Rf values in two different solvent systems.

  12. The friction of polymers around Tg,Tm : Preliminary results

    DEFF Research Database (Denmark)

    Sivebæk, Ion Marius; Samoilov, V N; Persson, B N J

    We present Molecular Dynamics calculations involving polymers of different lengths. Polymers with lengths from 20 to 1400 carbon atoms are considered. The systems are able to simulate friction between polymer surfaces and polymer against metal. The results we present are very preliminary and they...

  13. Preliminary In Vivo Experiments on Adhesion of Geckos

    Directory of Open Access Journals (Sweden)

    N. Pugno

    2008-09-01

    Full Text Available We performed preliminary experiments on the adhesion of a Tokay gecko on surfaces with different roughness, with or without particles with significant different granulometry, before/after or during the moult. The results were analyzed using the Weibull statistics.

  14. A New Silver Complex with Ofloxacin – Preliminary Study

    Directory of Open Access Journals (Sweden)

    Rusu Aura

    2016-06-01

    Full Text Available Objective: Silver complexes of antibacterial quinolones have the potential advantage of combining the antibacterial activity of silver and fluoroquinolones. The objective of our study was the preparation and the preliminary physico-chemical characterization of a silver complex with ofloxacin.

  15. Preliminary design package for solar collector and solar pump

    Science.gov (United States)

    1978-01-01

    A solar-operated pump using an existing solar collector, for use on solar heating and cooling and hot water systems is described. Preliminary design criteria of the collector and solar-powered pump is given including: design drawings, verification plans, and hazard analysis.

  16. Preliminary Investigation of a Video-Based Stimulus Preference Assessment

    Science.gov (United States)

    Snyder, Katie; Higbee, Thomas S.; Dayton, Elizabeth

    2012-01-01

    Video clips may be an effective format for presenting complex stimuli in preference assessments. In this preliminary study, we evaluated the correspondence between preference hierarchies generated from preference assessments that included either toys or videos of the toys. The top-ranked item corresponded in both assessments for 5 of the 6…

  17. Reprocessing of spent fuel from AHWR: preliminary batch studies

    International Nuclear Information System (INIS)

    Scheme for the reprocessing of spent fuel from advanced heavy water reactor (AHWR) is under development. Present paper describes the results of some of the preliminary batch studies carried out to collect the data required for conducting counter-current studies. Studies are carried out using simulated solutions and include data on extraction as well as stripping. (author)

  18. Cognitive behavioral therapy for insomnia comorbid with COPD is feasible with preliminary evidence of positive sleep and fatigue effects

    Directory of Open Access Journals (Sweden)

    Kapella MC

    2011-11-01

    Full Text Available Mary C Kapella1, James J Herdegen2, Michael L Perlis3, Joan L Shaver4, Janet L Larson5, Julie A Law2, David W Carley11Center for Narcolepsy, Sleep and Health Research, Department of Biobehavioral Science, College of Nursing, 2Section of Pulmonary, Critical Care, Sleep and Allergy, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA; 3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA; 4College of Nursing, University of Arizona, Tucson, AZ, USA; 5Division of Acute, Critical and Long Term Care Programs, University of Michigan School of Nursing, Ann Arbor, MI, USABackground: Many people with COPD report difficulties falling asleep or staying asleep, insufficient sleep duration, or nonrestorative sleep. Cognitive behavioral therapy for insomnia (CBT-I has proved effective not only in people with primary insomnia but also in people with insomnia comorbid with psychiatric and medical illness (eg, depression, cancer, and chronic pain. However, CBT-I has rarely been tested in those with COPD who have disease-related features that interfere with sleep and may lessen the effectiveness of such therapies. The purpose of this study was to determine the feasibility of applying a CBT-I intervention for people with COPD and to assess the impact of CBT-I on insomnia severity and sleep-related outcomes, fatigue, mood, and daytime functioning.Methods: The study had two phases. In Phase 1, a 6-weekly session CBT-I intervention protocol in participants with COPD was assessed to examine feasibility and acceptability. Phase 2 was a small trial utilizing a prospective two-group pre- and post-test design with random assignment to the six-session CBT-I or a six-session wellness education (WE program to determine the effects of each intervention, with both interventions being provided by a nurse behavioral sleep medicine specialist.Results: Fourteen participants (five in Phase 1 and nine in Phase 2 completed six sessions of CBT-I and nine participants completed six sessions of WE. Participants indicated that both interventions were acceptable. Significant positive treatment-related effects of the CBT-I intervention were noted for insomnia severity (P = 0.000, global sleep quality (P = 0.002, wake after sleep onset (P = 0.03, sleep efficiency (P = 0.02, fatigue (P = 0.005, and beliefs and attitudes about sleep (P = 0.000. Significant positive effects were noted for depressed mood after WE (P = 0.005.Conclusion: Results suggest that using CBT-I in COPD is feasible and the outcomes compare favorably with those obtained in older adults with insomnia in the context of other chronic illnesses.Keywords: CBT-I, emphysema, chronic bronchitis, sleep disturbance

  19. Wesley says: a children’s response inhibition playground training game yields preliminary evidence of transfer effects

    Directory of Open Access Journals (Sweden)

    Xin eZhao

    2015-02-01

    Full Text Available Recent studies suggest that the response inhibition ability of children can be modified through training. Based on the notion of embodied cognition, we investigated transfer effects of a 7-day training program using a game named Wesley says in 8- to 12-year-old children (n = 15. The game consists of providing commands for performing simple body actions, the actual execution of which is conditional upon the preceding verbal expression Wesley says. Training effects were assessed with a computer-based visual go/no-go task and the Stroop color-word interference task. Relative to a control group playing other games mainly involving physical exercise (n = 15, the trained group showed a performance improvement on the go/no-go task, but not on the Stroop task. These results suggest the potential of an easy-to-use and ecologically valid training game to improve the inhibition capacity of children on related response inhibition tasks but not on tasks measuring other aspects of inhibition, such as interference control.

  20. Wesley says: a children’s response inhibition playground training game yields preliminary evidence of transfer effects

    OpenAIRE

    Xin eZhao; Ling eChen; Lily eFu; Joseph Hubertus Roald Maes

    2015-01-01

    Recent studies suggest that the response inhibition ability of children can be modified through training. Based on the notion of embodied cognition, we investigated transfer effects of a 7-day training program using a game named Wesley says in 8- to 12-year-old children (n = 15). The game consists of providing commands for performing simple body actions, the actual execution of which is conditional upon the preceding verbal expression Wesley says. Training effects were assessed with a compute...

  1. How "Central" Is Central Coherence?: Preliminary Evidence on the Link between Conceptual and Perceptual Processing in Children with Autism

    Science.gov (United States)

    Lopez, Beatriz; Leekam, Susan R.; Arts, Gerda R. J.

    2008-01-01

    This study aimed to test the assumption drawn from weak central coherence theory that a central cognitive mechanism is responsible for integrating information at both conceptual and perceptual levels. A visual semantic memory task and a face recognition task measuring use of holistic information were administered to 15 children with autism and 16…

  2. Distribution and autecology of chrysophyte cysts from high Arctic Svalbard lakes: preliminary evidence of recent environmental change

    OpenAIRE

    Betts-Piper, Alexandra M.; Zeeb, Barbara A.; John P. Smol

    2004-01-01

    Chrysophycean stomatocyst assemblages were analysed from the sediments of 17 lakes and ponds from Svalbard as one component of a multi-proxy investigation of recent environmental change in the high Arctic. Sediment cores and water chemistry were collected from each of the study lakes, and chrysophyte stomatocysts were investigated from the top 0.25 cm of sediment (present-day) and bottom (i.e. bottom of short sediment core, pre-industrial) sediment samples. This study represents the first und...

  3. Combining Major Life Events and Recurrent Hassles in the Assessment of Stress in Chinese Adolescents: Preliminary Evidence

    Science.gov (United States)

    Cheng, Sheung-Tak; Li, Kin-Kit

    2010-01-01

    Major life events and hassles have been considered 2 distinct constructs in the measurement of stress. Research also shows that chronic events are more impactful than time-limited ones. This study reports a new approach to measuring stress in which major life events are combined with recurrent hassles to form a single index--the Adolescent Stress…

  4. Preliminary Evidence for Impaired Brain Activity of Neural Reward Processing in Children and Adolescents with Reactive Attachment Disorder.

    Science.gov (United States)

    Tomoda, Akemi

    2016-01-01

    Childhood maltreatment, which markedly increases risks for psychopathology, is associated with structural and functional brain differences. Especially, exposure to parental verbal abuse (PVA) or interparental violence during childhood is associated with negative outcomes such as depression, posttraumatic stress disorder (PTSD), and reduced cognitive abilities. Other forms of childhood maltreatment have been associated with brain structure or developmental alteration. Our earlier studies elucidated potential discernible effects of PVA and witnessing domestic violence during childhood on brain morphology, including gray matter volume or cortical thickness. Brain regions that process and convey the adverse sensory input of the abuse might be modified specifically by such experiences, particularly in subjects exposed to a single type of maltreatment. Exposure to multiple types of maltreatment is more commonly associated with morphological alterations in the corticolimbic regions. These findings fit with preclinical studies showing that sensory cortices are highly plastic structures. Using tasks with high and low monetary rewards while subjects underwent functional MRI, we also examined whether neural activity during reward processing was altered, or not, in children and adolescents with reactive attachment disorder (RAD). Significantly reduced activity in the caudate and nucleus accumbens was observed during a high monetary reward condition in the RAD group compared to the typically developed group. The striatal neural reward activity in the RAD group was also markedly decreased. The present results suggest that dopaminergic dysfunction occurred in the striatum in children and adolescents with RAD, potentially leading to a future risk of psychiatric disorders such as dependence. PMID:27150924

  5. Neurophysiological correlates of response inhibition predict relapse in detoxified alcoholic patients: some preliminary evidence from event-related potentials

    Directory of Open Access Journals (Sweden)

    Petit G

    2014-06-01

    Full Text Available Géraldine Petit, Agnieszka Cimochowska, Charles Kornreich, Catherine Hanak, Paul Verbanck, Salvatore CampanellaLaboratory of Psychological Medicine and Addictology, ULB Neuroscience Institute (UNI, Université Libre de Bruxelles (ULB, Brussels, BelgiumBackground: Alcohol dependence is a chronic relapsing disease. The impairment of response inhibition and alcohol-cue reactivity are the main cognitive mechanisms that trigger relapse. Despite the interaction suggested between the two processes, they have long been investigated as two different lines of research. The present study aimed to investigate the interaction between response inhibition and alcohol-cue reactivity and their potential link with relapse.Materials and methods: Event-related potentials were recorded during a variant of a “go/no-go” task. Frequent and rare stimuli (to be inhibited were superimposed on neutral, nonalcohol-related, and alcohol-related contexts. The task was administered following a 3-week detoxification course. Relapse outcome was measured after 3 months, using self-reported abstinence. There were 27 controls (seven females and 27 patients (seven females, among whom 13 relapsed during the 3-month follow-up period. The no-go N2, no-go P3, and the “difference” wave (P3d were examined with the aim of linking neural correlates of response inhibition on alcohol-related contexts to the observed relapse rate.Results: Results showed that 1 at the behavioral level, alcohol-dependent patients made significantly more commission errors than controls (P<0.001, independently of context; 2 through the subtraction no-go P3 minus go P3, this inhibition deficit was neurophysiologically indexed in patients with greater P3d amplitudes (P=0.034; and 3 within the patient group, increased P3d amplitude enabled us to differentiate between future relapsers and nonrelapsers (P=0.026.Conclusion: Our findings suggest that recently detoxified alcoholics are characterized by poorer response-inhibition skills that demand greater neural resources. We propose that event-related potentials can be used in conjunction with behavioral data to predict relapse; this would identify patients that need a higher level of neural resources when suppressing a response is requested.Keywords: alcoholism, relapse, response inhibition, go/no-go task, ERPs, P3d 

  6. Preliminary Evidence on the Diagnostic and Molecular Role of Circulating Soluble EGFR in Non-Small Cell Lung Cancer

    Directory of Open Access Journals (Sweden)

    Filippo Lococo

    2015-08-01

    Full Text Available Assessment of biological diagnostic factors providing clinically-relevant information to guide physician decision-making are still needed for diseases with poor outcomes, such as non-small cell lung cancer (NSCLC. Epidermal growth factor receptor (EGFR is a promising molecule in the clinical management of NSCLC. While the EGFR transmembrane form has been extensively investigated in large clinical trials, the soluble, circulating EGFR isoform (sEGFR, which may have a potential clinical use, has rarely been considered. This study investigates the use of sEGFR as a potential diagnostic biomarker for NSCLC and also characterizes the biological function of sEGFR to clarify the molecular mechanisms involved in the course of action of this protein. Plasma sEGFR levels from a heterogeneous cohort of 37 non-advanced NSCLC patients and 54 healthy subjects were analyzed by using an enzyme-linked immunosorbent assay. The biological function of sEGFR was analyzed in vitro using NSCLC cell lines, investigating effects on cell proliferation and migration. We found that plasma sEGFR was significantly decreased in the NSCLC patient group as compared to the control group (median value: 48.6 vs. 55.6 ng/mL respectively; p = 0.0002. Moreover, we demonstrated that sEGFR inhibits growth and migration of NSCLC cells in vitro through molecular mechanisms that included perturbation of EGF/EGFR cell signaling and holoreceptor internalization. These data show that sEGFR is a potential circulating biomarker with a physiological protective role, providing a first approach to the functional role of the soluble isoform of EGFR. However, the impact of these data on daily clinical practice needs to be further investigated in larger prospective studies.

  7. Preliminary evidence that yoga practice progressively improves mood and decreases stress in a sample of UK prisoners

    NARCIS (Netherlands)

    Bilderbeck, A.C.; Brazil, I.A.; Farias, M.

    2015-01-01

    Objectives. In the first randomized controlled trial of yoga on UK prisoners, we previously showed that yoga practice was associated with improved mental wellbeing and cognition. Here, we aimed to assess how class attendance, self-practice, and demographic factors were related to outcome amongst pri

  8. Preliminary Evidence That Yoga Practice Progressively Improves Mood and Decreases Stress in a Sample of UK Prisoners

    Directory of Open Access Journals (Sweden)

    Amy C. Bilderbeck

    2015-01-01

    Full Text Available Objectives. In the first randomized controlled trial of yoga on UK prisoners, we previously showed that yoga practice was associated with improved mental wellbeing and cognition. Here, we aimed to assess how class attendance, self-practice, and demographic factors were related to outcome amongst prisoners enrolled in the 10-week yoga intervention. Methods. The data of 55 participants (52 male, 3 female who completed a 10-week yoga course were analysed. Changes in pre- and postyoga measures of affect, perceived stress, and psychological symptoms were entered into linear regression analyses with bias-corrected and accelerated bootstrap confidence intervals. Class attendance, self-practice, demographic variables, and baseline psychometric variables were included as regressors. Results. Participants who attended more yoga classes and those who engaged in frequent (5 times or more self-practice reported significantly greater decreases in perceived stress. Decreases in negative affect were also significantly related to high frequency self-practice and greater class attendance at a near-significant level. Age was positively correlated with yoga class attendance, and higher levels of education were associated with greater decreases in negative affect. Conclusions. Our results suggest that there may be progressive beneficial effects of yoga within prison populations and point to subpopulations who may benefit the most from this practice.

  9. Preliminary evidence that allelic variation in the LMX1A gene influences training-related working memory improvement.

    Science.gov (United States)

    Bellander, Martin; Brehmer, Yvonne; Westerberg, Helena; Karlsson, Sari; Fürth, Daniel; Bergman, Olle; Eriksson, Elias; Bäckman, Lars

    2011-06-01

    LMX1A is a transcription factor involved in the development of dopamine (DA)-producing neurons in midbrain. Previous research has shown that allelic variations in three LMX1A single nucleotide polymorphisms (SNPs) were related to risk of Parkinson's disease (PD), suggesting that these SNPs may influence the number of mesencephalic DA neurons. Prompted by the established link between striatal DA functions and working memory (WM) performance, we examined two of these SNPs in relation to the ability to benefit from 4 weeks of WM training. One SNP (rs4657412) was strongly associated with the magnitude of training-related gains in verbal WM. The allele linked to larger gains has previously been suggested to be associated with higher dopaminergic nerve cell density. No differential gains of either SNP were observed for spatial WM, and the genotype groups were also indistinguishable in tests of attention, interference control, episodic memory, perceptual speed, and reasoning for both SNPs. This pattern of data is in agreement with previous findings from our group, suggesting that cognitive effects of DA-related genes may be more easily detected in a training context than for single-assessment performance scores. PMID:21435346

  10. Building Emotion and Affect Regulation (BEAR): Preliminary Evidence from an Open Trial in Children's Residential Group Homes in Singapore

    Science.gov (United States)

    Pat-Horenczyk, R.; Shi, C. Sim Wei; Schramm-Yavin, S.; Bar-Halpern, M.; Tan, L. J.

    2015-01-01

    Background: The Building Emotion and Affect Regulation (BEAR) program is a theory-based group intervention for enhancing resilience in children, with a focus on strengthening emotion regulation. The BEAR is a 6-session protocol for children aged 7-12 who have been subject to traumatic life events. Objective: This paper presents the guiding…

  11. Cognitive behavioral therapy for insomnia comorbid with COPD is feasible with preliminary evidence of positive sleep and fatigue effects

    OpenAIRE

    Kapella MC; Herdegen JJ; Perlis ML; Shaver JL; Larson JL; Law JA; Carley DW

    2011-01-01

    Mary C Kapella1, James J Herdegen2, Michael L Perlis3, Joan L Shaver4, Janet L Larson5, Julie A Law2, David W Carley11Center for Narcolepsy, Sleep and Health Research, Department of Biobehavioral Science, College of Nursing, 2Section of Pulmonary, Critical Care, Sleep and Allergy, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA; 3Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA; 4College of Nursing, University of Arizona, Tucson, AZ, USA; 5D...

  12. Preliminary evidence that exercise dependence is associated with blunted cardiac and cortisol reactions to acute psychological stress

    OpenAIRE

    Heaney, Jennifer L. J.; Ginty, Annie T; Carroll, Douglas; Phillips, Anna C

    2011-01-01

    Low or blunted cardiovascular and cortisol reactions to acute psychological stress have been shown to characterise those with a tobacco or alcohol dependency. The present study tested the hypothesis that exercise dependency would be similarly associated with blunted reactivity. Young female exercisers (N = 219) were screened by questionnaire for exercise dependence. Ten women with probable exercise dependence and 10 non dependent controls were selected for laboratory stress testing....

  13. Preliminary evidence for the cross-cultural utility of the type D personality construct in the Ukraine

    DEFF Research Database (Denmark)

    Pedersen, Susanne S.; Yagensky, Andriy; Smith, Otto R F; Yagenska, Oksana; Shpak, Volodymyr; Denollet, Johan

    2009-01-01

    Type D personality is a risk indicator in cardiac patients. The validity and reliability of the Type D Scale (DS14) have been confirmed in Western Europe but not outside this context.......Type D personality is a risk indicator in cardiac patients. The validity and reliability of the Type D Scale (DS14) have been confirmed in Western Europe but not outside this context....

  14. Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network

    Science.gov (United States)

    Adiponectin is an adipose-secreted protein that has been linked to changes in insulin sensitivity, high-density lipoprotein cholesterol levels, and inflammatory patterns. Although fenofibrate therapy can raise adiponectin levels, treatment response is heterogeneous and heritable, suggesting a role f...

  15. Preliminary Evidence That Yoga Practice Progressively Improves Mood and Decreases Stress in a Sample of UK Prisoners.

    Science.gov (United States)

    Bilderbeck, Amy C; Brazil, Inti A; Farias, Miguel

    2015-01-01

    Objectives. In the first randomized controlled trial of yoga on UK prisoners, we previously showed that yoga practice was associated with improved mental wellbeing and cognition. Here, we aimed to assess how class attendance, self-practice, and demographic factors were related to outcome amongst prisoners enrolled in the 10-week yoga intervention. Methods. The data of 55 participants (52 male, 3 female) who completed a 10-week yoga course were analysed. Changes in pre- and postyoga measures of affect, perceived stress, and psychological symptoms were entered into linear regression analyses with bias-corrected and accelerated bootstrap confidence intervals. Class attendance, self-practice, demographic variables, and baseline psychometric variables were included as regressors. Results. Participants who attended more yoga classes and those who engaged in frequent (5 times or more) self-practice reported significantly greater decreases in perceived stress. Decreases in negative affect were also significantly related to high frequency self-practice and greater class attendance at a near-significant level. Age was positively correlated with yoga class attendance, and higher levels of education were associated with greater decreases in negative affect. Conclusions. Our results suggest that there may be progressive beneficial effects of yoga within prison populations and point to subpopulations who may benefit the most from this practice. PMID:26294928

  16. Prospective memory impairment in chemotherapy-exposed early breast cancer survivors: Preliminary evidence from a clinical test.

    Science.gov (United States)

    Bedard, Marc; Verma, Shailendra; Collins, Barbara; Song, Xinni; Paquet, Lise

    2016-01-01

    We report the results of a secondary analysis of a cross-sectional study (Paquet et al., 2013 ) to evaluate the cognitive operations involved in prospective memory (PM) deficits exhibited by chemotherapy-exposed breast cancer (BC) survivors. PM was assessed with the memory for intentions screening test administered to 80 patients and 80 healthy controls. Patients performed worse than controls on the PM tasks and had more "omission" errors (indices of the prospective component of the tasks) than the controls. No group differences emerged on a recognition test. Although further studies will be needed to disentangle the multiple cognitive operations involved in PM, these findings are consistent with the notion that self-initiated retrieval processes rather than encoding are implicated in PM impairment among BC survivors. PMID:27123566

  17. Validity of the TAS-45 as a Measure of Toddler-Parent Attachment: Preliminary Evidence from Early Head Start Families

    OpenAIRE

    Spieker, Susan; Nelson, Elizabeth M.; Condon, Marie-Celeste

    2011-01-01

    A new observational measure of attachment strategies in the home, the Toddler Attachment Sort-45 (TAS-45) was completed for 59 18- to 36-month-old recipients of EHS. Mothers completed the Brief Infant Toddler Social and Emotional Assessment (BITSEA); children were tested on the Preschool Language Scale (PLS-4); and a mother-child snack was videotaped and coded for dyadic mutuality. The TAS-45 Security score was associated with more dyadic mutuality, higher language and competence scores, and ...

  18. Preliminary evidence for methamphetamine-induced behavioral and ocular effects in rat offspring following exposure during early organogenesis.

    Science.gov (United States)

    Acuff-Smith, K D; George, M; Lorens, S A; Vorhees, C V

    1992-01-01

    Gravid Sprague-Dawley CD (VAF) rats received 50 mg/kg (d,l)-methamphetamine (MA) HCl (expressed as free base, N = 15) or distilled water (N = 6) by SC injection x 2/day in a 3 ml/kg volume on embryonic (E) days 7-12. Control rats were pair-fed to MA-exposed dams on days E7-18. No control dams failed to deliver; however, of 15 MA-exposed dams 4 did not deliver (2 died and 2 had completely resorbed litters). One additional MA litter had all the offspring die shortly after birth. There was no difference between groups on offspring postnatal (P) body weight. The offspring exposed prenatally to MA had significantly lower olfactory orientation scores (P9, 11, 13) to their home cage scent. In a test of early activity (P10, 12, 14) the MA-exposed progeny were marginally less active than controls. MA-exposed offspring exhibited hyperreactivity and marginally shortened response latency on a test of acoustic startle (P27). Motor activity showed no differential response in MA treated or control offspring to MA (P63) or fluoxetine challenge (P70). However, the MA offspring were more active than controls with respect to central and side activity during the second week of testing. No group differences were found for performance in a straight swimming channel or on the number of errors committed or latency to escape in a complex (Cincinnati) water maze (P84). Prenatal exposure to MA also induced eye defects (i.e., anophthalmia, microphthalmia and folded retina) in 16.7% of the progeny. However, MA did not effect hippocampal or neostriatal monoamine levels when measured on P28.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1365624

  19. Preliminary Evidence Regarding the Hypothesis That the Sex Ratio at Sexual Maturity May Affect Longevity in Men

    OpenAIRE

    Jin, Lei; Elwert, Felix; Freese, Jeremy; Christakis, Nicholas A.

    2010-01-01

    In human populations, variation in mate availability has been linked to various biological and social outcomes, but the possible effect of mate availability on health or survival has not been studied. Unbalanced sex ratios are a concern in many parts of the world, and their implications for the health and survival of the constituent individuals warrant careful investigation. We indexed mate availability with contextual sex ratios and investigated the hypothesis that the sex ratio at sexual ma...

  20. A systematic literature search on psychological first aid: lack of evidence to develop guidelines.

    Directory of Open Access Journals (Sweden)

    Tessa Dieltjens

    Full Text Available BACKGROUND: Providing psychological first aid (PFA is generally considered to be an important element in preliminary care of disaster victims. Using the best available scientific basis for courses and educational materials, the Belgian Red Cross-Flanders wants to ensure that its volunteers are trained in the best way possible. OBJECTIVE: To identify effective PFA practices, by systematically reviewing the evidence in existing guidelines, systematic reviews and individual studies. METHODS: Systematic literature searches in five bibliographic databases (MEDLINE, PsycINFO, The Cochrane Library, PILOTS and G-I-N were conducted from inception to July 2013. RESULTS: Five practice guidelines were included which were found to vary in the development process (AGREE II score 20-53% and evidence base used. None of them provides solid evidence concerning the effectiveness of PFA practices. Additionally, two systematic reviews of PFA were found, both noting a lack of studies on PFA. A complementary search for individual studies, using a more sensitive search strategy, identified 11 237 references of which 102 were included for further full-text examination, none of which ultimately provides solid evidence concerning the effectiveness of PFA practices. CONCLUSION: The scientific literature on psychological first aid available to date, does not provide any evidence about the effectiveness of PFA interventions. Currently it is impossible to make evidence-based guidelines about which practices in psychosocial support are most effective to help disaster and trauma victims.

  1. 75 FR 20813 - Certain Magnesia Carbon Bricks from the People's Republic of China: Amended Preliminary...

    Science.gov (United States)

    2010-04-21

    ... Determination, 75 FR 11847 (March 12, 2010) (``Preliminary Determination''). We are amending our Preliminary... International Trade Administration Certain Magnesia Carbon Bricks from the People's Republic of China: Amended... value (``LTFV'') in the antidumping duty investigation of certain magnesia carbon bricks...

  2. 78 FR 9687 - Prineville Energy Storage, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2013-02-11

    ... Energy Regulatory Commission Prineville Energy Storage, LLC; Notice of Preliminary Permit Application..., 2012, Prineville Energy Storage, LLC, filed an application for a preliminary permit, pursuant to...-hours. Applicant Contact: Mr. Matthew Shapiro, Chief Executive Officer, Prineville Energy Storage,...

  3. 76 FR 42682 - High Pressure Steel Cylinders From the People's Republic of China: Postponement of Preliminary...

    Science.gov (United States)

    2011-07-19

    ... From the People's Republic of China: Initiation of Countervailing Duty Investigation, 76 FR 33239 (June 8, 2011). Currently, the preliminary determination is due no later than August 4, 2011. Postponement...: Postponement of Preliminary Determination in the Countervailing Duty Investigation AGENCY:...

  4. 76 FR 6459 - Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-02-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted.... On December 30, 2010, Mahoning Hydropower, LLC filed an application for a preliminary...

  5. 76 FR 7838 - Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-02-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted.... On December 30, 2010, Mahoning Hydropower, LLC filed an application for a preliminary...

  6. 75 FR 8320 - Coastal Hydropower LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-02-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Coastal Hydropower LLC; Notice of Preliminary Permit Application Accepted.... On November 5, 2009, Coastal Hydropower LLC filed an application for a preliminary permit,...

  7. 76 FR 61695 - Gulf of Mexico Regional Ecosystem Restoration Strategy (Preliminary)

    Science.gov (United States)

    2011-10-05

    ... AGENCY Gulf of Mexico Regional Ecosystem Restoration Strategy (Preliminary) AGENCY: Environmental... the Gulf of Mexico Regional Ecosystem Restoration Strategy (Preliminary) for public review and... Mexico Ecosystem Restoration Strategy. Additionally, the Task Force was instructed to build upon...

  8. Controlled comparison of three interventions for mother and toddler problems: preliminary communication.

    OpenAIRE

    Nicol, A. R.; D. D. Stretch; Davison, I.; Fundudis, T

    1984-01-01

    This paper summarizes the preliminary thinking, the hypotheses and design and some preliminary results of a large community-based intervention project which is currently underway in the North East of England.

  9. 78 FR 33345 - Certain Frozen Warmwater Shrimp From Malaysia: Preliminary Countervailing Duty Determination

    Science.gov (United States)

    2013-06-04

    ... International Trade Administration Certain Frozen Warmwater Shrimp From Malaysia: Preliminary Countervailing... shrimp) from Malaysia. The period of investigation (POI) is January 1, 2011, through December 31, 2011... Malaysia,'' dated concurrently with this notice (Preliminary Decision Memorandum). For this...

  10. Preliminary paleoseismic observations along the western Denali fault, Alaska

    Science.gov (United States)

    Koehler, R. D.; Schwartz, D. P.; Rood, D. H.; Reger, R.; Wolken, G. J.

    2013-12-01

    The Denali fault in south-central Alaska, from Mt. McKinley to the Denali-Totschunda fault branch point, accommodates ~9-12 mm/yr of the right-lateral component of oblique convergence between the Pacific/Yakutat and North American plates. The eastern 226 km of this fault reach was part of the source of the 2002 M7.9 Denali fault earthquake. West of the 2002 rupture there is evidence of two large earthquakes on the Denali fault during the past ~550-700 years but the paleoearthquake chronology prior to this time is largely unknown. To better constrain fault rupture parameters for the western Denali fault and contribute to improved seismic hazard assessment, we performed helicopter and ground reconnaissance along the southern flank of the Alaska Range between the Nenana Glacier and Pyramid Peak, a distance of ~35 km, and conducted a site-specific paleoseismic study. We present a Quaternary geologic strip map along the western Denali fault and our preliminary paleoseismic results, which include a differential-GPS survey of a displaced debris flow fan, cosmogenic 10Be surface exposure ages for boulders on this fan, and an interpretation of a trench across the main trace of the fault at the same site. Between the Nenana Glacier and Pyramid Peak, the Denali fault is characterized by prominent tectonic geomorphic features that include linear side-hill troughs, mole tracks, anastamosing composite scarps, and open left-stepping fissures. Measurements of offset rills and gullies indicate that slip during the most recent earthquake was between ~3 and 5 meters, similar to the average displacement in the 2002 earthquake. At our trench site, ~ 25 km east of the Parks Highway, a steep debris fan is displaced along a series of well-defined left-stepping linear fault traces. Multi-event displacements of debris-flow and snow-avalanche channels incised into the fan range from 8 to 43 m, the latter of which serves as a minimum cumulative fan offset estimate. The trench, excavated into

  11. Evidence-Based Practice and School Nursing

    Science.gov (United States)

    Adams, Susan; McCarthy, Ann Marie

    2005-01-01

    School nurses need to demonstrate that their practice is based on the best evidence available, which is usually data obtained from research. Evidence-based practice involves combining the best evidence available with nursing expertise and patient and family preferences to determine optimum care. Evidence-based practice guidelines are developed by…

  12. 22 CFR 224.34 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Evidence. 224.34 Section 224.34 Foreign....34 Evidence. (a) The ALJ shall determine the admissibility of evidence. (b) Except as provided in this part, the ALJ shall not be bound by the Federal Rules of Evidence. However, the ALJ may apply...

  13. 16 CFR 1025.43 - Evidence.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Evidence. 1025.43 Section 1025.43 Commercial... § 1025.43 Evidence. (a) Applicability of Federal Rules of Evidence. Unless otherwise provided by statute or these rules, the Federal Rules of Evidence shall apply to all proceedings held pursuant to...

  14. 42 CFR 426.540 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 426.540 Section 426.540 Public Health... § 426.540 Evidence. (a) Except as provided in this part, the Board is not bound by the Federal Rules of Evidence. However, the Board may apply the Federal Rules of Evidence when appropriate, for example,...

  15. 45 CFR 213.25 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Evidence. 213.25 Section 213.25 Public Welfare... Evidence. (a) Testimony. Testimony shall be given orally under oath or affirmation by witnesses at the... hearing if the presiding officer so requires. (c) Rules of evidence. Technical rules of evidence shall...

  16. 31 CFR 315.23 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Evidence. 315.23 Section 315.23 Money... Caveats Permitted § 315.23 Evidence. (a) General. To establish the validity of judicial proceedings... supported by appropriate evidence of appointment and qualification. The evidence must be certified by...

  17. 34 CFR 81.15 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Evidence. 81.15 Section 81.15 Education Office of the... Evidence. (a) The Federal Rules of Evidence do not apply to proceedings under this part. However, the ALJ accepts only evidence that is— (1) Relevant; (2) Material; (3) Not unduly repetitious; and (4)...

  18. 42 CFR 422.678 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 422.678 Section 422.678 Public Health... PROGRAM MEDICARE ADVANTAGE PROGRAM Medicare Contract Determinations and Appeals § 422.678 Evidence. The hearing officer rules on the admissibility of evidence and may admit evidence that would be...

  19. 42 CFR 422.1048 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Evidence. 422.1048 Section 422.1048 Public Health... PROGRAM MEDICARE ADVANTAGE PROGRAM Appeal procedures for Civil Money Penalties § 422.1048 Evidence. Evidence may be received at the hearing even though inadmissible under the rules of evidence applicable...

  20. 40 CFR 27.34 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Evidence. 27.34 Section 27.34... Evidence. (a) The presiding officer shall determine the admissibility of evidence. (b) Except as provided in this part, the presiding officer shall not be bound by the Federal Rules of Evidence. However,...