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Sample records for ames test

  1. NASA Ames Sonic Boom Testing

    Science.gov (United States)

    Durston, Donald A.; Kmak, Francis J.

    2009-01-01

    Multiple sonic boom wind tunnel models were tested in the NASA Ames Research Center 9-by 7-Foot Supersonic Wind Tunnel to reestablish related test techniques in this facility. The goal of the testing was to acquire higher fidelity sonic boom signatures with instrumentation that is significantly more sensitive than that used during previous wind tunnel entries and to compare old and new data from established models. Another objective was to perform tunnel-to-tunnel comparisons of data from a Gulfstream sonic boom model tested at the NASA Langley Research Center 4-foot by 4-foot Unitary Plan Wind Tunnel.

  2. A Classroom Modification of the Ames Test.

    Science.gov (United States)

    Yavornitzky, Joseph; Trzeciak, Victor

    1979-01-01

    A modification of the Ames test for detecting carcinogens and mutagens using a strain of bacteria is described. A suggestion is given for checking the correctness of procedures by using particular hair dyes which have been shown to be mutogenic. (Author/SA)

  3. PSP Testing at NASA Ames Research Center

    Science.gov (United States)

    Bell, J. H.; Hand, L. A.; Schairer, E. T.; Mehta, R. D.; George, Michael W. (Technical Monitor)

    1997-01-01

    Pressure sensitive paints (PSPs) are now used routinely for measuring surface pressures on wind tunnel models at transonic and supersonic Mach numbers. The method utilizes a surface coating containing fluorescent or phosphorescent materials, the brightness of which varies with the local air pressure on the surface. The present paper will summarize PSP activities (in progress and planned) at the NASA Ames Research Center. One of the main accomplishments at NASA Ames has been the development of a PSP measurement system that is production testing capable. This system has been integrated successfully into the large-scale wind tunnel facilities at Ames. There are several problems related to PSP testing which are unique to large-scale wind tunnel testing. The hardware is often difficult to set-up and must operate under harsh conditions (e.g. high pressures and low temperatures). The data acquisition and reduction times need to be kept to a minimum so that the overall wind tunnel productivity is not compromised. The pressure sensitive paints needs to be very robust; the paints must readily adhere to different surfaces with varying geometries and remain functional for long running times. The paint must have well understood, and preferably minimal, temperature sensitivity since fine control of the tunnel temperature is not easily achievable in the larger wind tunnels. In an effort to improve the overall accuracy of the PSP technique, we are currently evaluating some referenced pressure sensitive paints which contain a pressure- independent luminophor in addition to the one which is affected by the surface pressure. The two luminophors are chosen so that their emission wavelengths are somewhat different. Then by taking two 'wind-on' images with either two cameras (with different filters) or one camera with a rotating filter system, the need for 'wind-off' images can be eliminated. The ratio of the two wind-on images accounts for nonuniform lighting and model motion problems

  4. Evolutionary Ensemble for In Silico Prediction of Ames Test Mutagenicity

    Science.gov (United States)

    Chen, Huanhuan; Yao, Xin

    Driven by new regulations and animal welfare, the need to develop in silico models has increased recently as alternative approaches to safety assessment of chemicals without animal testing. This paper describes a novel machine learning ensemble approach to building an in silico model for the prediction of the Ames test mutagenicity, one of a battery of the most commonly used experimental in vitro and in vivo genotoxicity tests for safety evaluation of chemicals. Evolutionary random neural ensemble with negative correlation learning (ERNE) [1] was developed based on neural networks and evolutionary algorithms. ERNE combines the method of bootstrap sampling on training data with the method of random subspace feature selection to ensure diversity in creating individuals within an initial ensemble. Furthermore, while evolving individuals within the ensemble, it makes use of the negative correlation learning, enabling individual NNs to be trained as accurate as possible while still manage to maintain them as diverse as possible. Therefore, the resulting individuals in the final ensemble are capable of cooperating collectively to achieve better generalization of prediction. The empirical experiment suggest that ERNE is an effective ensemble approach for predicting the Ames test mutagenicity of chemicals.

  5. Estimation of γ irradiation induced genetic damage by Ames test

    International Nuclear Information System (INIS)

    Mutation by 60 Co γ irradiation was studied in five different histidine-requiring auxotrophs of Salmonella typhimurium. The strains TA98 (sensitive to frameshift) and TA100 (sensitive to base-pair substitution) were irradiated (10-84 Gy and 45-317 Gy, respectively) and revertants were counted. TA98 exhibited radiation-induced revertants, 2.8 fold of spontaneous revertants, although no significant increase was detected in TA100. Then, three other frameshift-sensitive strains TA1537, TA1538 and TA94 were irradiated in a dose of 61-167 Gy. Only in TA94, revertants increased 3.5 fold. Since spontaneous revertants are known to be independent of cell density, a decrease of bacterial number by γ irradiation was confirmed not to affect the induced revertants by dilution test. Thus the standard Ames Salmonella assay identified γ irradiation was confirmed not to affect the induced revertants by dilution test. Thus the standard Ames Salmonella assay identified γ irradiation as a mutagenetic agent. The mutagenicity of dinitropyrene, a mutagen widely existing in food, and dismutagenicity of boiling water insoluble fraction of Hizikia fusiforme, edible marine alga, were tested on γ induced revertant formation in TA98 and TA94. Dinitropyrene synergistically increased γ induced revertants and Hizikia insoluble fraction reduced the synergistic effect of dinitropyrene dependently on the concentration. (author)

  6. Flight Test 4 Preliminary Results: NASA Ames SSI

    Science.gov (United States)

    Isaacson, Doug; Gong, Chester; Reardon, Scott; Santiago, Confesor

    2016-01-01

    Realization of the expected proliferation of Unmanned Aircraft System (UAS) operations in the National Airspace System (NAS) depends on the development and validation of performance standards for UAS Detect and Avoid (DAA) Systems. The RTCA Special Committee 228 is charged with leading the development of draft Minimum Operational Performance Standards (MOPS) for UAS DAA Systems. NASA, as a participating member of RTCA SC-228 is committed to supporting the development and validation of draft requirements as well as the safety substantiation and end-to-end assessment of DAA system performance. The Unmanned Aircraft System (UAS) Integration into the National Airspace System (NAS) Project conducted flight test program, referred to as Flight Test 4, at Armstrong Flight Research Center from April -June 2016. Part of the test flights were dedicated to the NASA Ames-developed Detect and Avoid (DAA) System referred to as JADEM (Java Architecture for DAA Extensibility and Modeling). The encounter scenarios, which involved NASA's Ikhana UAS and a manned intruder aircraft, were designed to collect data on DAA system performance in real-world conditions and uncertainties with four different surveillance sensor systems. Flight test 4 has four objectives: (1) validate DAA requirements in stressing cases that drive MOPS requirements, including: high-speed cooperative intruder, low-speed non-cooperative intruder, high vertical closure rate encounter, and Mode CS-only intruder (i.e. without ADS-B), (2) validate TCASDAA alerting and guidance interoperability concept in the presence of realistic sensor, tracking and navigational errors and in multiple-intruder encounters against both cooperative and non-cooperative intruders, (3) validate Well Clear Recovery guidance in the presence of realistic sensor, tracking and navigational errors, and (4) validate DAA alerting and guidance requirements in the presence of realistic sensor, tracking and navigational errors. The results will be

  7. Evaluation of aromatic amines with different purities and different solvent vehicles in the Ames test.

    Science.gov (United States)

    Harding, Alexander P; Popelier, Paul L A; Harvey, James; Giddings, Amanda; Foster, Graham; Kranz, Michael

    2015-03-01

    Of all the in vitro mutagenicity assays, the Ames test displays the best correlation with rodent carcinogenicity and therefore carries significant weight with the food and drug regulatory bodies. Aromatic amines (AA) are ubiquitous structural groups in food and drug molecules despite the well-documented mutagenic and carcinogenic propensity for many representatives. Furthermore, recent regulatory guidelines (that is ICH M7) requires the hazard assessment of actual and potential impurities by two complementary (Q)SAR prediction methodologies if no carcinogenicity or bacterial mutagenicity data is available. One methodology should be expert-rule-based and the second should be statistics-based. Having encountered numerous reports of contradictory Ames results for members of this chemotype, we undertook systematic Ames tests on a diverse set of 14 AAs of differing purities in different solvents, and as free bases and their salts. The aim of this work was to investigate the reliability of the Ames test for this chemotype leading to the creation of a reference set of AAs for use by medicinal chemists and in silico modelling. Contrary to previous experience, which led to the investigations reported in this publication, the anticipated transformation from an Ames-positive to an Ames-negative after purification only occurred for one compound. Furthermore, this result proved inconclusive after testing as the HCl salt in DMSO and in water. The anticipated change in class from mutagen to non-mutagen, did not occur and this can be read as evidence for the reliability of the Ames test for AAs. PMID:25542092

  8. Low-speed wind tunnel testing of the NPS/NASA Ames Mach 6 optimized waverider

    OpenAIRE

    Cedrun, Mark E.

    1994-01-01

    Low-speed wind tunnel tests were conducted to determine the subsonic aerodynamic characteristics of an optimized supersonic (Mach 6) conical-flow waverider designed for a deck-launched intercept mission. These tests are part of the continuing waverider research being conducted by the Naval Postgraduate School and the NASA Ames Research Center. The tests consisted of performing Alpha and Beta sweeps, at different dynamic pressures, with a 15 inch aluminum waverider model in the NPS low-speed w...

  9. Investigating the Mutagenic Effects of Three Commonly Used Pulpotomy Agents Using the Ames Test

    Directory of Open Access Journals (Sweden)

    Mohammad Samiei

    2015-03-01

    Full Text Available Purpose: The mutagenic potency of materials used in dentistry is of great concern. The Ames test is a bacterial reverse mutation assay, which is used to determine the mutagenicity potential of chemicals. In this study, the Ames test was used to compare mutagenic effects of three pulpotomy agents, namely, CEM cement, formocresol and ferric sulfate. Methods: TA100 strain of Salmonella typhimurium was used to evaluate mutagenicity of different concentrations of pulpotomy materials in the presence and absence of enzymatic system found in rat liver S9 fraction. Negative controls were 1% dimethyl sulfoxide and water. The positive controls were sodium azide and 2-aminoanthracene. The number of colonies per plate was counted. The material was regarded mutagenic if the number of histidine revertant colonies was twice or more than the spontaneous revertant colonies (Ames mutagenicity ratio. Results: Ferric sulfate was found mutagenic in the concentrations prepared by addition of 50 μL of its 1 in 100 and 1 in 1000 times diluted solutions to the culture medium in the absence of S9 fraction (Ames test ratios of 2.8 and 2.2, respectively. Formocresol showed strong toxicity toward TA100 strain of S. typhimurium up to the concentration as low achieved using 1000 times diluted solution of the original preparation, particularly in the presence of S9 fraction. Ames assay failed to detect significant reverse mutations in all the concentrations of CEM cement. Conclusion: In contrast to formocresol and ferric sulfate, CEM cement is a less toxic and non-mutagenic agent.

  10. Investigating the Mutagenic Effects of Three Commonly Used Pulpotomy Agents Using the Ames Test

    Science.gov (United States)

    Samiei, Mohammad; Asgary, Saeed; Farajzadeh, Malak; Bargahi, Nasrin; Abdolrahimi, Majid; Kananizadeh, Usef; Dastmalchi, Siavoush

    2015-01-01

    Purpose: The mutagenic potency of materials used in dentistry is of great concern. The Ames test is a bacterial reverse mutation assay, which is used to determine the mutagenicity potential of chemicals. In this study, the Ames test was used to compare mutagenic effects of three pulpotomy agents, namely, CEM cement, formocresol and ferric sulfate. Methods: TA100 strain of Salmonella typhimurium was used to evaluate mutagenicity of different concentrations of pulpotomy materials in the presence and absence of enzymatic system found in rat liver S9 fraction. Negative controls were 1% dimethyl sulfoxide and water. The positive controls were sodium azide and 2-aminoanthracene. The number of colonies per plate was counted. The material was regarded mutagenic if the number of histidine revertant colonies was twice or more than the spontaneous revertant colonies (Ames mutagenicity ratio). Results: Ferric sulfate was found mutagenic in the concentrations prepared by addition of 50 µL of its 1 in 100 and 1 in 1000 times diluted solutions to the culture medium in the absence of S9 fraction (Ames test ratios of 2.8 and 2.2, respectively). Formocresol showed strong toxicity toward TA100 strain of S. typhimurium up to the concentration as low achieved using 1000 times diluted solution of the original preparation, particularly in the presence of S9 fraction. Ames assay failed to detect significant reverse mutations in all the concentrations of CEM cement. Conclusion: In contrast to formocresol and ferric sulfate, CEM cement is a less toxic and non-mutagenic agent. PMID:25789229

  11. Use of the modified Ames test as an indicator of the carcinogenicity of residual aromatic extracts

    Energy Technology Data Exchange (ETDEWEB)

    Boogaard, P.; Hedelin, A.; Riley, A.; Rushton, E.; Vaissiere, M.; Minsavage, G.; Rohde, A.; Dalbey, W.

    2013-01-15

    Existing data demonstrate that residual aromatic extracts (RAEs) can be either carcinogenic or non-carcinogenic. CONCAWE had previously concluded that 'Although limited data available indicate that some RAEs are weakly carcinogenic, it is not possible to provide a general recommendation. Classify on a case-by-case basis' (CONCAWE 2005). Therefore CONCAWE's Health/Toxicology Subgroup (H/TSG) has developed a proposal for the use of the modified Ames test as a short-term predictive screening tool for decisions on the classification of RAEs for carcinogenicity. The relationship between RAE chemistry and carcinogenic potential is not as well understood as it is for some other categories of substances, e.g. Other Lubricant Base Oils (OLBO). However, a correlation has been found between the results of the skin carcinogenicity bioassay and the mutagenicity index (MI) obtained from the modified Ames test. Data supporting this correlation are summarised in this report. The H/TSG confirmed that the modified Ames test can be used as a predictive screening tool and that a cut-off value can be established to make a distinction between carcinogenic and non-carcinogenic products. RAEs with a MI > 0.4 demonstrated carcinogenic potential upon dermal application to mouse skin with chronic exposure. RAEs with a MI > 0.4 did not demonstrate a carcinogenic potential. To justify the use of the modified Ames test with RAEs, additional analysis of the repeatability of the test with RAEs was required. With this objective, CONCAWE sponsored a round robin study with different samples of RAEs from member companies, at three different laboratories. The repeatability demonstrated in the round robin study with RAEs support the proposed use of the modified Ames test. As part of the tools available for use by member companies, the H/TSG proposed a standard operating procedure (SOP) (included as an Appendix to this report) on the conduct of the modified Ames test with RAEs. The H

  12. Testing of SLA-561V in NASA-Ames' Turbulent Flow Duct with Augmented Radiative Heating

    Science.gov (United States)

    Sepka, Steven A.; Kornienko, Robert S.; Radbourne, Chris A.

    2010-01-01

    As part of Mars Science Laboratory s (MSL) heatshield development program, SLA-561 was tested in NASA Ames Turbulent Flow Duct (TFD) Facility. For these tests, the TFD facility was modified to include a ceramic plate located in the wall opposite to the test model. Normally the TFD wall opposite to the test model is water-cooled steel. Installing a noncooled ceramic plate allows the ceramic to absorb convective heating and radiate the energy back to the test model as the plate heats up. This work was an effort to increase the severity of TFD test conditions. Presented here are the results from these tests.

  13. Direct comparison of the Ames microplate format (MPF) test in liquid medium with the standard Ames pre-incubation assay on agar plates by use of equivocal to weakly positive test compounds.

    Science.gov (United States)

    Flückiger-Isler, Sini; Kamber, Markus

    2012-08-30

    The Ames microplate format (MPF™) test, which uses liquid media and in 384-well microplates with a readout based on a colour-change, has been used for over 10 years at several major pharmaceutical companies for screening the genotoxic potential of early drug candidates when compound supply is minimal. Meanwhile, Xenometrix has adapted this screen from the two-strain Ames II test for use with five tester strains, in compliance with OECD Guideline 471. A set of 15 equivocal to weakly positive chemicals selected from the National Toxicology Program (NTP) database was tested simultaneously in the Ames microplate format (MPF) and the standard Ames pre-incubation method on agar plates. Such a direct comparison of the two test methods with the same overnight culture(s), chemicals and S9-mix preparation should exclude external variability factors. Thirteen of the 15 chemicals showed concordant results in both tests despite the choice of chemicals that showed varying inter- and even intra-laboratory results in the NTP studies. These results indicate that the Ames MPF™ assay is a reliable predictive tool that can be used like the regular Ames test to evaluate compounds for mutagenicity. PMID:22579797

  14. Fluoro-A-85380 demonstrated no mutagenic properties in in vivo rat micronucleus and Ames tests

    International Nuclear Information System (INIS)

    The potential mutagenic properties (micronucleus and the Ames tests) of fluoro-A-85380 (2-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine) were evaluated as a mandatory pre-clinical step. No statistically significant increase in the frequency of micronucleated polychromatic erythrocytes was found in animals treated at any dose tested. No biologically significant increase in the mean number of revertants was noted in all the Salmonella typhimurium strains tested with fluoro-A-85380. Therefore, fluoro-A-85380 demonstrated no mutagenic properties using these two tests

  15. Application of the Ames Mutagenicity Test to Food Processed by Physical Preservation Methods

    International Nuclear Information System (INIS)

    An irradiated (380 krad) mixture of four fresh vegetables - leek, celery, carrot, and cauliflower - was examined for mutagenicity by the Ames mutagenicity test using four different histidine-deficient strains of Salmonellae. Water extracts were prepared from the irradiated and unirradiated vegetables - a freeze dried extract (FDE) and a boiled extract (BE). Several problems were overcome in the mutagenicity testing of a complex substance such as food which contains free histidine, different species of bacteria, and a mixture of low and high molecular weight chemicals. In addition, we eliminated an omission in the usual protocols of the Ames test by testing the positive mutagen controls in the presence and absence of the test samples, thus reducing the possible incidence of false negatives and false positives. The induction and expression of mutagenesis by sodium azide (SA) and ethidium bromide (EB) in TA 100 and TA 98 mutant strains, respectively, decreased with increasing amounts of FDE, while increasing levels of BE suppressed the number of revertants in TA 98 in the presence of EB, but exerted little influence on the mutagenicity of SA in TA 100. No difference was observed in the antimutagenic action between the irradiated and unirradiated vegetable extracts. Both the FDE and BE preparations suppressed the action of a frameshift mutagen, but with a base-pair mutagen only the FDE or uncooked vegetable extracts produced suppression. (author)

  16. Application of the Ames mutagenicity test to food processed by physical preservation methods

    International Nuclear Information System (INIS)

    An irradiated (380 krad) mixture of four fresh vegetables - leek, celery, carrot, and cauliflower - was examined for mutagenicity by the Ames mutagenicity test using four different histidine-deficient strains of Salmonellae. Water extracts were prepared from the irradiated and unirradiated vegetables - a freeze dried extract (FDE) and a boiled extract (BE). Several problems were overcome in the mutagenicity testing of a complex substance such as food which contains free histidine, different species of bacteria, and a mixture of low and high molecular weight chemicals. In addition, we eliminated an omission in the usual protocols of the Ames test by testing the positive mutagen controls in the presence and absence of the test samples, thus reducing the possible incidence of false negatives and false positives. The induction and expression of mutagenesis by sodium azide (SA) and ethidium bromide (EB) in TA 100 and TA 98 mutant strains, respectively, decreased with increasing amounts of FDE, while increasing levels of BE suppressed the number of revertants in TA 98 in the presence of EB, but exerted little influence on the mutagenicity of SA in TA 100. No difference was observed in the antimutagenic action between the irradiated and unirradiated vegetable extracts. Both the FDE and BE preparations suppressed the action of a frameshift mutagen, but with a base-pair mutagen only the FDE or uncooked vegetable extracts produced suppression. (author)

  17. Dynamic Calibration of the NASA Ames Rotor Test Apparatus Steady/Dynamic Rotor Balance

    Science.gov (United States)

    Peterson, Randall L.; vanAken, Johannes M.

    1996-01-01

    The NASA Ames Rotor Test Apparatus was modified to include a Steady/Dynamic Rotor Balance. The dynamic calibration procedures and configurations are discussed. Random excitation was applied at the rotor hub, and vibratory force and moment responses were measured on the steady/dynamic rotor balance. Transfer functions were computed using the load cell data and the vibratory force and moment responses from the rotor balance. Calibration results showing the influence of frequency bandwidth, hub mass, rotor RPM, thrust preload, and dynamic loads through the stationary push rods are presented and discussed.

  18. AN INVESTIGATION OF MUTAGENIC ACTIVITIES OF SOME 9- SUBSTITUEDPHENANTHRENE DERIVATIVES WITH AMES / SALMONELLA / MICROSOME TEST

    Directory of Open Access Journals (Sweden)

    Mehtap KUTLU

    2011-02-01

    Full Text Available In this study, three different 9-Substituted phenantrene derivatives that were synthesized to be used as basic matter for drugs were tested for their mutagenic potency in strains TA 98 and TA 100 ofSalmonella typhimurium by using Ames test. Therefore, both strains were tested in the absence or presence of S9 metabolic activation, for five different doses of each test substances in two paralel independent experiments. In the absence of metabolic activation, while only one of the compounds were causing frame-shift mutations, two of them were determined to induce base pair substitution mutations. In the presence of metabolic activation, while two of the compounds were mutagenic for TA 98, base pair substitution mutations were not detected for any of the substances. Each of the compoundstested were found to be mutagenic for at least one strain in the presence or absence of S9.

  19. The Use of the Ames Test as a Tool for Addressing Problem-Based Learning in the Microbiology Lab

    Directory of Open Access Journals (Sweden)

    Eliana Rodríguez

    2012-08-01

    Full Text Available Our environment is full of potential carcinogens such as UV light, industrial pollutants, pesticides, and food additives, among others. It is estimated that 90% of all carcinogens are also mutagens. The Ames test is one of the most common tests for mutagens. In this problem-based learning activity, undergraduate biology students used the Ames test to screen a substance they provided, to see if it could be considered a mutagen. The idea of surveying substances used in everyday life appealed to our students, and helped engage them in this activity.

  20. Mutagenic activity of a fluorinated analog of the beta-adrenoceptor ligand carazolol in the Ames test

    International Nuclear Information System (INIS)

    S-1'[18F]-Fluorocarazolol (FCAR) is a fluorinated analog of the nonmutagenic beta-blocker carazolol (CAR). In former studies FCAR proved to be suitable for quantification of beta-adrenoceptors in vivo with positron emission tomography (PET). We report here that FCAR displays no acute toxicity in either rats or mice. However, FCAR induces a strong dose-related increase in the number of revertants in the Ames test. We conclude that FCAR yields mutagenic activity as measured by the Ames test

  1. Genotoxic, Cytotoxic, Antigenotoxic, and Anticytotoxic Effects of Sulfonamide Chalcone Using the Ames Test and the Mouse Bone Marrow Micronucleus Test.

    Directory of Open Access Journals (Sweden)

    Carolina Ribeiro E Silva

    Full Text Available Chalcones present several biological activities and sulfonamide chalcone derivatives have shown important biological applications, including antitumor activity. In this study, genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of the sulfonamide chalcone N-{4-[3-(4-nitrophenylprop-2-enoyl]phenyl} benzenesulfonamide (CPN were assessed using the Salmonella typhimurium reverse mutation test (Ames test and the mouse bone marrow micronucleus test. The results showed that CPN caused a small increase in the number of histidine revertant colonies in S. typhimurium strains TA98 and TA100, but not statistically significant (p > 0.05. The antimutagenicity test showed that CPN significantly decreased the number of His+ revertants in strain TA98 at all doses tested (p 0.05. Additionally, CPN co-administered with MMC significantly increased PCE/NCE ratio at all doses tested, demonstrating its anticytotoxic effect. In summary, CPN presented genotoxic, cytotoxic, antigenotoxic, and anticytotoxic properties.

  2. Supersonic Retropropulsion CFD Validation with Ames Unitary Plan Wind Tunnel Test Data

    Science.gov (United States)

    Schauerhamer, Daniel G.; Zarchi, Kerry A.; Kleb, William L.; Edquist, Karl T.

    2013-01-01

    A validation study of Computational Fluid Dynamics (CFD) for Supersonic Retropropulsion (SRP) was conducted using three Navier-Stokes flow solvers (DPLR, FUN3D, and OVERFLOW). The study compared results from the CFD codes to each other and also to wind tunnel test data obtained in the NASA Ames Research Center 90 70 Unitary PlanWind Tunnel. Comparisons include surface pressure coefficient as well as unsteady plume effects, and cover a range of Mach numbers, levels of thrust, and angles of orientation. The comparisons show promising capability of CFD to simulate SRP, and best agreement with the tunnel data exists for the steadier cases of the 1-nozzle and high thrust 3-nozzle configurations.

  3. Analysis of plant extracts antimutagenicity using the Ames test and the cytogenetic analysis of peripheral blood lymphocytes

    Czech Academy of Sciences Publication Activity Database

    Buňková, R.; Marová, I.; Pokorná, Z.; Lojek, Antonín

    2005-01-01

    Roč. 11, č. 2 (2005), s. 107-112. ISSN 1082-0132 Institutional research plan: CEZ:AV0Z50040507 Keywords : plant extracts * antioxidative activity * Ames test Subject RIV: BO - Biophysics Impact factor: 0.724, year: 2005

  4. Evaluation of genotoxicity of Trois through Ames and in vitro chromosomal aberration tests

    Institute of Scientific and Technical Information of China (English)

    Manu Chaudhary; Anurag Payasi

    2013-01-01

    Objective: To investigate the mutagenic potential of Trois using the bacterial reverse mutation assay (Ames test) and in vitro chromosomal aberration test.Methods:typhimurium (TA 98, TA100, TA1535 and TA1537) and Escherichia coli (WP2 uvrA) with and without metabolic activation system (S9 mix) at the dose range of 313 to 5000 µg/plate. Chromosomal aberrations were evaluated in Chinese hamster lung (CHL) cell line at the dose levels of 15, 7.5, 3.7, 1.9 and 0.9 mg/mL in the absence and presence of S9 mix.Results:The ability of Trois to induce reverse mutations was evaluated in Salmonella Trois used in the study with and without S9 mix in all tester strains. Trois did not produce any structural aberration in CHL cells in the presence or absence of S9 mix. There were no increases in the number of revertant colonies at any concentrations of Conclusions: Results of this study suggest that Trois is non-mutagenic.

  5. Mutagenesis by ionizing radiation in strains of Salmonella typhimurium used in the Ames test

    International Nuclear Information System (INIS)

    A study has been made of γ-induced back mutation to prototropy of the hisC3076 marker of Salmonella. Although the numbers of induced mutants per plate were relatively small, the numbers of induced mutants per 108 survivors were clearly dose-related, increasing to a maximum at about 45 krad and then declining; it is suggested that this decline at higher doses probably reflects killing of potential mutants. Tests were also made on the effects of three N group plasmids, R205, R46 and pKM101 on reversion of the hisC3076 marker following U.V. and γ-irradiation. Results showed that all three plasmids enhance reversion of this frameshift marker, and to approximately the same extent, with U.V. appearing more effective than γ-irradiation. Two of the most important strains in the Ames series (TA98 and TA100) were found to be reverted by γ-irradiation, and for each strain there was an increase in the absolute numbers of mutants per plate as well as an increase in the numbers of induced mutants per 108 survivors. (U.K.)

  6. The metabolic activation of 2-naphthylamine to mutagens in the Ames test.

    Science.gov (United States)

    Tong, S; Smith, J; Manson, D; Gorrod, J W; Ioannides, C

    1986-01-01

    The mutagenicity of 2-naphthylamine and its major metabolites in the Ames test was determined in the absence and presence of activation systems derived from rats and hamsters. In the absence of an activation system only N-hydroxy-2-naphthylamine and 2-nitrosonaphthalene were mutagenic. In the presence of activation systems derived from control and 3-methylcholanthrene-treated hamsters and Arochlor 1254-treated rats only 2-naphthylamine exhibited a mutagenic response while its hydroxy-derivatives and 2-acetamidonaphthalene were devoid of mutagenicity. Pretreatment of rats with 3-methylcholanthrene or Arochlor 1254 enhanced the mutagenicity of 2-naphthylamine while treatments with phenobarbitone, safrole and clofibrate had no significant effect. In the hamster treatment with only 3-methylcholanthrene increased the mutagenicity of 2-naphthylamine. It is concluded that the metabolic activation of 2-naphthylamine proceeds via N-hydroxylation which is preferentially catalysed by the 3-methylcholanthrene inducible forms of cytochrome P-450, whereas ring-hydroxylation appears to be a deactivation pathway. PMID:3800318

  7. A critical review of the life sciences project management at Ames Research Center for the Spacelab Mission development test 3

    Science.gov (United States)

    Helmreich, R. L.; Wilhelm, J. M.; Tanner, T. A.; Sieber, J. E.; Burgenbauch, S. F.

    1979-01-01

    A management study was initiated by ARC (Ames Research Center) to specify Spacelab Mission Development Test 3 activities and problems. This report documents the problems encountered and provides conclusions and recommendations to project management for current and future ARC life sciences projects. An executive summary of the conclusions and recommendations is provided. The report also addresses broader issues relevant to the conduct of future scientific missions under the constraints imposed by the space environment.

  8. SYBR Gold and SYBR Green II are not mutagenic in the Ames test.

    Science.gov (United States)

    Kirsanov, Kirill I; Lesovaya, Ekaterina A; Yakubovskaya, Marianna G; Belitsky, Gennady A

    2010-06-17

    Favorable photo-physical properties and high affinity to nucleic acids make new fluorescent cyanine dyes of the SYBR-type particularly useful for DNA and RNA visualization. The growing popularity of SYBR-type dyes is also explained by the fact that removal of the dye from the nucleic acids by ethanol precipitation is more efficient and less time-consuming than the phenol-chloroform extraction applied for the widely used phenanthridine DNA stain, ethidium bromide. To evaluate the safety of nucleic acid staining by SYBR Gold and SYBR Green II we compared the mutagenicity of these compounds, with characteristics corresponding to those of ethidium bromide, by use of the Salmonella/mammalian microsome reverse-mutation assays (Ames test). SYBR Green II and SYBR Gold did not show mutagenicity either in frame-shift or in base-substitution indicator strains, TA98 and TA100, respectively. These results were observed both in the presence and in the absence of supernatant from a rat-liver homogenate S9. Mutagenicity of these stains was not observed although their toxic concentration was reached. Toxic effects of SYBR Green II and SYBR Gold were seen approximately at the same molar concentrations as reported previously for SYBR Green I. As expected, ethidium bromide revealed strong mutagenicity with a maximum increase of 60-fold above the vehicle controls in the frame-shift indicator strain TA98 in the presence of rat-liver S9 extract. Thus, SYBR Gold and SYBR Green II do not show mutagenicity in our tests, even at toxic doses, and these DNA stains represent safer alternatives to ethidium bromide for nucleic acid visualization. PMID:20403457

  9. Ames Research Center Shear Tests of SLA-561V Heat Shield Material for Mars-Pathfinder

    Science.gov (United States)

    Tauber, Michael; Tran, Huy; Henline, William; Cartledge, Alan; Hui, Frank; Tran, Duoc; Zimmerman, Norm

    1996-01-01

    This report describes the results of arc-jet testing at Ames Research Center on behalf of Jet Propulsion Laboratory (JPL) for the development of the Mars-Pathfinder heat shield. The current test series evaluated the performance of the ablating SLA-561V heat shield material under shear conditions. In addition, the effectiveness of several methods of repairing damage to the heat shield were evaluated. A total of 26 tests were performed in March 1994 in the 2 in. X 9 in. arc-heated turbulent Duct Facility, including runs to calibrate the facility to obtain the desired shear stress conditions. A total of eleven models were tested. Three different conditions of shear and heating were used. The non-ablating surface shear stresses and the corresponding, approximate, non-ablating surface heating rates were as follows: Condition 1, 170 N/m(exp 2) and 22 W/cm(exp 2); Condition 2, 240 N/m(exp 2) and 40 W/cm(exp 2); Condition 3, 390 N/m(exp 2) and 51 W/cm(exp 2). The peak shear stress encountered in flight is represented approximately by Condition 1; however, the heating rate was much less than the peak flight value. The peak heating rate that was available in the facility (at Condition 3) was about 30 percent less than the maximum value encountered during flight. Seven standard ablation models were tested, of which three models were instrumented with thermocouples to obtain in-depth temperature profiles and temperature contours. An additional four models contained a variety of repair plugs, gaps, and seams. These models were used to evaluated different repair materials and techniques, and the effect of gaps and construction seams. Mass loss and surface recession measurements were made on all models. The models were visually inspected and photographed before and after each test. The SLA-561 V performed well; even at test Condition 3, the char remained intact. Most of the resins used for repairs and gap fillers performed poorly. However, repair plugs made of SLA-561V performed

  10. Autonomy @ Ames

    Science.gov (United States)

    Van Dalsem, William; Krishnakumar, Kalmanje Srinivas

    2016-01-01

    This is a powerpoint presentation that highlights autonomy across the 15 NASA technology roadmaps, including specific examples of projects (past and present) at NASA Ames Research Center. The NASA technology roadmaps are located here: http:www.nasa.govofficesocthomeroadmapsindex.html

  11. Large-scale V/STOL testing. [conducted in the Ames 40- by 80-foot wind tunnel

    Science.gov (United States)

    Koenig, D. G.; Aiken, T. N.; Aoyagi, K.; Falarshi, M. D.

    1977-01-01

    Several facets of large-scale testing of V/STOL aircraft configurations are discussed with particular emphasis on test experience in the Ames 40- by 80-Foot Wind Tunnel. Examples of powered-lift test programs are presented in order to illustrate tradeoffs confronting the planner of V/STOL test programs. Large-scale V/STOL wind-tunnel testing can sometimes compete with small-scale testing in the effort required (overall test time) and program costs because of the possibility of conducting a number of different tests with a single large-scale model where several small-scale models would be required. The benefits of both high- or full-scale Reynolds numbers, more detailed configuration simulation, and number and type of onboard measurements are studied.

  12. Preliminary Computational Study for Future Tests in the NASA Ames 9 foot' x 7 foot Wind Tunnel

    Science.gov (United States)

    Pearl, Jason M.; Carter, Melissa B.; Elmiligui, Alaa A.; WInski, Courtney S.; Nayani, Sudheer N.

    2016-01-01

    The NASA Advanced Air Vehicles Program, Commercial Supersonics Technology Project seeks to advance tools and techniques to make over-land supersonic flight feasible. In this study, preliminary computational results are presented for future tests in the NASA Ames 9 foot x 7 foot supersonic wind tunnel to be conducted in early 2016. Shock-plume interactions and their effect on pressure signature are examined for six model geometries. Near- field pressure signatures are assessed using the CFD code USM3D to model the proposed test geometries in free-air. Additionally, results obtained using the commercial grid generation software Pointwise Reigistered Trademark are compared to results using VGRID, the NASA Langley Research Center in-house mesh generation program.

  13. Study of the mechanism of carcinogenesis by carcinogens which are negative in the Ames test. Progress report, April 1-September 1, 1979

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-01-01

    Carcinogens ethionine, thioacetamide, and actinomycin D, all of which are negative in the Ames test and all of which raise the progesterone level in the chicken, were tested to determine their physiological role in carcinogenesis. The optimization of the carcinogenesis model also included evaluation of the chicken as the biological indicator of physiological changes relative to the above compounds. (PCS)

  14. Differential effects of chronic alcohol administration to rats on the activation of aromatic amines to mutagens in the Ames test.

    Science.gov (United States)

    Steele, C M; Ioannides, C

    1986-05-01

    Male Wistar albino rats were maintained on alcohol-containing liquid diets for 4 weeks. Hepatic post-mitochondrial preparations derived from these animals were more efficient than control in activating 4-aminobiphenyl and 2-aminofluorene to mutagens in the Ames test. The alcohol-induced enhancement in mutagenicity was not inhibited by dimethylsulphoxide indicating that the generation of hydroxyl radicals is not involved. The activation of 2-naphthylamine was not affected by the treatment with alcohol but the mutagenicities of 2-aminoanthracene, benzo[a]pyrene and 3-methylcholanthrene were inhibited. The same treatment markedly increased hepatic microsomal aniline p-hydroxylase and ethoxyresorufin O-de-ethylase activities and to a lesser extent benzphetamine N-demethylase and microsomal levels of total cytochromes P-450. It is concluded that chronic alcohol administration to rats modulates the metabolic activation of pre-carcinogens to their reactive intermediates presumably by causing the redistribution of cytochrome P-450 isozymes. PMID:3009048

  15. On Laminar to Turbulent Transition of Arc-Jet Flow in the NASA Ames Panel Test Facility

    Science.gov (United States)

    Gokcen, Tahir; Alunni, Antonella I.

    2012-01-01

    This paper provides experimental evidence and supporting computational analysis to characterize the laminar to turbulent flow transition in a high enthalpy arc-jet facility at NASA Ames Research Center. The arc-jet test data obtained in the 20 MW Panel Test Facility include measurements of surface pressure and heat flux on a water-cooled calibration plate, and measurements of surface temperature on a reaction-cured glass coated tile plate. Computational fluid dynamics simulations are performed to characterize the arc-jet test environment and estimate its parameters consistent with the facility and calibration measurements. The present analysis comprises simulations of the nonequilibrium flowfield in the facility nozzle, test box, and flowfield over test articles. Both laminar and turbulent simulations are performed, and the computed results are compared with the experimental measurements, including Stanton number dependence on Reynolds number. Comparisons of computed and measured surface heat fluxes (and temperatures), along with the accompanying analysis, confirm that that the boundary layer in the Panel Test Facility flow is transitional at certain archeater conditions.

  16. Evaluation of 4-methylimidazole, in the Ames/Salmonella test using induced rodent liver and lung S9.

    Science.gov (United States)

    Beevers, Carol; Adamson, Richard H

    2016-01-01

    4-methylimidazole (4-MeI) is formed by the interaction of ammonia with reducing sugars and low levels have been identified as a by-product in coffee, soy sauce, wine, dark beers, soft drinks, and caramel colors. The 4-MeI has been reported to induce alveolar/bronchiolar tumors in mice but not rats. Its mechanism of action is unlikely to be due to genotoxicity as 4-MeI does not induce mutation in Salmonella typhimurium and does not induce micronuclei in rodent peripheral erythrocytes or bone marrow cells. However, the question of whether genetically reactive intermediates could be formed via lung-specific metabolism has not previously been addressed. The 4-MeI was tested for its ability to induce mutation in five standard Ames strains of S. typhimurium using induced rat (F344/N) and mouse (B6C3F1) liver and lung S9 as a source of exogenous metabolism. The chemicals were tested in an OECD 471-compliant bacterial reverse mutation assay, using both plate-incorporation and pre-incubation methodologies, together with 10% S-9 metabolic activation. No induction of mutation (as measured by an increase in revertant colonies) was observed and it was concluded that 4-MeI was not mutagenic in S. typhimurium using either rodent liver or lung S9 for exogenous metabolism. PMID:26765635

  17. Situational judgement tests in medical education and training: Research, theory and practice: AMEE Guide No. 100.

    Science.gov (United States)

    Patterson, Fiona; Zibarras, Lara; Ashworth, Vicki

    2016-01-01

    Why use SJTs? Traditionally, selection into medical education professions has focused primarily upon academic ability alone. This approach has been questioned more recently, as although academic attainment predicts performance early in training, research shows it has less predictive power for demonstrating competence in postgraduate clinical practice. Such evidence, coupled with an increasing focus on individuals working in healthcare roles displaying the core values of compassionate care, benevolence and respect, illustrates that individuals should be selected on attributes other than academic ability alone. Moreover, there are mounting calls to widen access to medicine, to ensure that selection methods do not unfairly disadvantage individuals from specific groups (e.g. regarding ethnicity or socio-economic status), so that the future workforce adequately represents society as a whole. These drivers necessitate a method of assessment that allows individuals to be selected on important non-academic attributes that are desirable in healthcare professionals, in a fair, reliable and valid way. What are SJTs? Situational judgement tests (SJTs) are tests used to assess individuals' reactions to a number of hypothetical role-relevant scenarios, which reflect situations candidates are likely to encounter in the target role. These scenarios are based on a detailed analysis of the role and should be developed in collaboration with subject matter experts, in order to accurately assess the key attributes that are associated with competent performance. From a theoretical perspective, SJTs are believed to measure prosocial Implicit Trait Policies (ITPs), which are shaped by socialisation processes that teach the utility of expressing certain traits in different settings such as agreeable expressions (e.g. helping others in need), or disagreeable actions (e.g. advancing ones own interest at others, expense). Are SJTs reliable, valid and fair? Several studies, including good

  18. Acoustic Modifications of the Ames 40x80 Foot Wind Tunnel and Test Techniques for High-Speed Research Model Testing

    Science.gov (United States)

    Soderman, Paul T.; Olson, Larry (Technical Monitor)

    1995-01-01

    The NFAC 40- by 80- Foot Wind Tunnel at Ames is being refurbished with a new, deep acoustic lining in the test section which will make the facility nearly anechoic over a large frequency range. The modification history, key elements, and schedule will be discussed. Design features and expected performance gains will be described. Background noise reductions will be summarized. Improvements in aeroacoustic research techniques have been developed and used recently at NFAC on several wind tunnel tests of High Speed Research models. Research on quiet inflow microphones and struts will be described. The Acoustic Survey Apparatus in the 40x80 will be illustrated. A special intensity probe was tested for source localization. Multi-channel, high speed digital data acquisition is now used for acoustics. And most important, phased microphone arrays have been developed and tested which have proven to be very powerful for source identification and increased signal-to-noise ratio. Use of these tools for the HEAT model will be illustrated. In addition, an acoustically absorbent symmetry plane was built to satisfy the HEAT semispan aerodynamic and acoustic requirements. Acoustic performance of that symmetry plane will be shown.

  19. Results of the AFRSI rewaterproofing systems screening test in the NASA/Ames Research Center (ARC) 2 x 2-foot transonic wind tunnel

    Science.gov (United States)

    Marroquin, J.; Kingsland, R. B.

    1985-01-01

    An experimental investigation was conducted in the NASA/Ames Research Center 2x2-foot Transonic Wind Tunnel to evaluate two AFRSI rewaterproofing systems and to investigate films as a means of reducing blanket joint distortion. The wind tunnel wall slot configuration influenced on the flow field over the test panel was investigated; primarily using oil flow data, and resulted in a closed slot configuration to provide a satisfactory screening environment flow field for the test. Sixteen AFRSI test panels, configured to represent the test system or film, were subjected to this screening environment (a flow field of separated and reattached flow at a freestream Mach numnber of 0.65 and q = 650 or 900 psf). Each condition was held until damage to the test article was observed or 55 minutes if no damage was incurred. All objectives related to AFRSI rewaterproofing and to the use of films to stiffen the blanket fibers were achieved.

  20. Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity?: I. Reports of individual databases presented at an EURL ECVAM Workshop

    OpenAIRE

    KIRKLAND David; Zeiger, Errol; MADIA FEDERICA; Gooderham, Nigel; Kasper, Peter; Lynch, Anthony; Morita, Takeshi(Department of Physics, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka, 422-8529, Japan); OUEDRAOGO G; PARRA MORTE Juan Manuel; Pfuhler, Stefan; Rogiers, Vera; Schulz, Markus; THYBAUD Veronique; Benthem, Jan Van; Vanparys, Philippe

    2014-01-01

    Positive results in the Ames test correlate well with carcinogenic potential, at least in rodents. However, the correlation is not perfect because mutagenesis is not carcinogenesis, and mutations are only one of many stages in tumour development. Also, situations can be envisaged where the mutagenic response may be specific to the bacteria or the test protocol, for example bacterial-specific metabolism, exceeding a detoxification threshold or the induction of oxidative damage to which bacteri...

  1. Thermal modeling of the NASA-Ames Research Center Cryogenic Optical Test Facility and a single-arch, fused-natural-quartz mirror

    Science.gov (United States)

    Ng, Y. S.; Augason, Gordon C.; Young, Jeffrey A.; Howard, Steven D.; Melugin, Ramsey K.

    1990-01-01

    A thermal model of the dewar and optical system of the Cryogenic Optical Test Facility at NASA-Ames Research Center was developed using the computer codes SINDA and MONTE CARLO. The model was based on the geometry, boundary conditions, and physical properties of the test facility and was developed to investigate heat transfer mechanisms and temperatures in the facility and in test mirrors during cryogenic optical tests. A single-arch, fused-natural-quartz mirror was the first mirror whose thermal loads and temperature distributions were modeled. From the temperature distribution, the thermal gradients in the mirror were obtained. The model predicted that a small gradient should exist for the single arch mirror. This was later verified by the measurement of mirror temperatures. The temperatures, predicted by the model at various locations within the dewar, were in relatively good agreement with the measured temperatures. The model is applicable to both steady-state and transient cooldown operations.

  2. Screening of a substance able to reduce gene damages caused by radiation. 1. Detection of gene damages caused by γ-ray by means of Ames test

    International Nuclear Information System (INIS)

    This study aimed to assess the mutagenicity of γ-ray by means of Ames test using Salmonella typhimurium. Production of revertant by γ-ray radiation was investigated with TA98 and TA100, ordinary indicator bacteria. Colony forming ability was determined to estimate the sensitivity to γ-ray. The sensitivity of either of the two strains showed complete linearity to the radiation dose, LD1 was 100 Gy for TA98 and 350 Gy for TA100. Although the mean number of revertant without radiation was 35 for TA98 and 63 for TA100, both of which were within the background range designated by the guideline for Ames test, it was indicated that TA98 produced revertants 2.5-3 times more than the background level at a dose ranging 10-84 Gy, whereas for TA100, the number of revertant was hardly increased by γ-radiation. Therefore, TA98 was thought to be available for screening a substance which reduces gene damages by γ-ray radiation. (M.N.)

  3. Genotoxicity assessment of NIM-76 and its formulation (pessary) in an in vitro Ames Salmonella/microsome assay and in vivo mouse bone marrow micronucleus test.

    Science.gov (United States)

    Vijayan, Vinod; Meshram, Ghansham P

    2013-10-01

    The possible genotoxic potential of NIM-76, a volatile fraction obtained from neem oil, having promising contraceptive activity, as well as its formulation product, called pessary (7.5% NIM-76 in polyethylene glycol), were evaluated in the Ames assay and mouse bone marrow micronucleus (MN) assay. Genotoxicity of NIM-76 (0.1-1000 µg/plate) and pessary (0.1-10,000 µg/plate) were studied using the liquid preincubation protocol of the Ames assay both in the presence and absence of S9. Likewise, the ability of NIM-76 [1-1000 mg/kg body weight (b.w.)] and its formulation product (18.75-300 mg/kg b.w.) to induce clastogenic effects were studied in the female mouse bone marrow MN test by using a two-dose intraperitoneal treatment protocol. There was no increase in the number of revertant colonies resulting from NIM-76 or pessary at any of their doses over the respective negative control plates, either in the presence or absence of S9. Similarly, in the MN assay, neither of them showed any clastogenic activity because there was no significant increase in the frequency of micronucleated polychromatic erythrocytes, over the negative control group of animals. The use of this compound in humans is therefore not likely to have mutagenic effects and may be considered as safe with regard to genotoxic potential. PMID:23527474

  4. Ames Research Center cryogenic mirror testing program - A comparison of the cryogenic performance of metal and glass mirrors with different types of mounts

    Science.gov (United States)

    Miller, Jacob H.; Melugin, Ramsey K.; Augason, Gordon C.; Howard, Steven D.; Pryor, G. Mark

    1989-01-01

    A summary of the cryogenic testing of glass and metal mirrors performed at NASA Ames Research Center (ARC) and two other places is presented. Recent improvements to the ARC Cryogenic Optics Test Facility are described. The purposes of the tests were to determine: (1) how glass mirrors would perform at cryogenic temperatures compared with metal mirrors and (2) how various mirror mounts would affect the cryogenic performance of mirrors. Details of a cryogenic test of a 50 cm 'double arch', fused-silica mirror with a three-point mount and with a radially-compliant, flexured mount are given. Within the accuracy of the measurements, it was determined that the flexured mount did not induce appreciable distortion in the double arch mirror. Results of the cryogenic tests of a number of glass mirrors and two beryllium mirrors are included. The cryogenic distortion of the glass mirrors was found to be less than that for the beryllium mirrors. Within the accuracy of the measurements, no hysteresis was found in the glass mirrors. It was possible to measure hysteresis in one of the beryllium mirrors.

  5. Aerodynamics, aeroelasticity, and stability of hang gliders. Experimental results. [Ames 7- by 10-ft wind tunnel tests

    Science.gov (United States)

    Kroo, I. M.

    1981-01-01

    One-fifth-scale models of three basic ultralight glider designs were constructed to simulate the elastic properties of full scale gliders and were tested at Reynolds numbers close to full scale values. Twenty-four minor modifications were made to the basic configurations in order to evaluate the effects of twist, reflex, dihedral, and various stability enhancement devices. Longitudinal and lateral data were obtained at several speeds through an angle of attack range of -30 deg to +45 deg with sideslip angles of up to 20 deg. The importance of vertical center of gravity displacement is discussed. Lateral data indicate that effective dihedral is lost at low angles of attack for nearly all of the configurations tested. Drag data suggest that lift-dependent viscous drag is a large part of the glider's total drag as is expected for thin, cambered sections at these relatively low Reynolds numbers.

  6. Assessment by Ames test and comet assay of toxicity potential of polymer used to develop field-capable rapid-detection device to analyze environmental samples

    Science.gov (United States)

    Hebert, Amanda; Bishop, Michelle; Bhattacharyya, Dhiman; Gleason, Karen; Torosian, Stephen

    2015-08-01

    There is need for devices that decrease detection time of food-borne pathogens from days to real-time. In this study, a rapid-detection device is being developed and assessed for potential cytotoxicity. The device is comprised of melt-spun polypropylene coupons coated via oxidative chemical vapor deposition (oCVD) with 3,4-Ethylenedioxythiophene (EDOT), for conductivity and 3-Thiopheneethanol (3TE), allowing antibody attachment. The Ames test and comet assay have been used in this study to examine the toxicity potentials of EDOT, 3TE, and polymerized EDOT-co-3TE. For this study, Salmonella typhimurium strain TA1535 was used to assess the mutagenic potential of EDOT, 3TE and the copolymer. The average mutagenic potential of EDOT, 3TE and copolymer was calculated to be 0.86, 0.56, and 0.92, respectively. For mutagenic potential, on a scale from 0 to 1, close to 1 indicates low potential for toxicity, whereas a value of 0 indicates a high potential for toxicity. The comet assay is a single-cell gel electrophoresis technique that is widely used for this purpose. This assay measures toxicity based on the area or intensity of the comet-like shape that DNA fragments produce when DNA damage has occurred. Three cell lines were assessed; FRhK-4, BHK-21, and Vero cells. After averaging the results of all three strains, the tail intensity of the copolymer was 8.8 % and tail moment was 3.0, and is most similar to the untreated control, with average tail intensity of 5.7 % and tail moment of 1.7. The assays conducted in this study provide evidence that the copolymer is non-toxic to humans.

  7. Routine environmental audit of Ames Laboratory, Ames, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-09-01

    This document contains the findings identified during the routine environmental audit of Ames Laboratory, Ames, Iowa, conducted September 12--23, 1994. The audit included a review of all Ames Laboratory operations and facilities supporting DOE-sponsored activities. The audit`s objective is to advise the Secretary of Energy, through the Assistant Secretary for Environment, Safety and Health, as to the adequacy of the environmental protection programs established at Ames Laboratory to ensure the protection of the environment, and compliance with Federal, state, and DOE requirements.

  8. Routine environmental audit of Ames Laboratory, Ames, Iowa

    International Nuclear Information System (INIS)

    This document contains the findings identified during the routine environmental audit of Ames Laboratory, Ames, Iowa, conducted September 12--23, 1994. The audit included a review of all Ames Laboratory operations and facilities supporting DOE-sponsored activities. The audit's objective is to advise the Secretary of Energy, through the Assistant Secretary for Environment, Safety and Health, as to the adequacy of the environmental protection programs established at Ames Laboratory to ensure the protection of the environment, and compliance with Federal, state, and DOE requirements

  9. Space Shuttle AFRSI OMS pod environment test using model 81-0 test fixture in the Ames Research Center 9x7-foot supersonic wind tunnel (OS-314A/B/C)

    Science.gov (United States)

    Collette, J. G. R.

    1984-01-01

    A test was conducted in the NASA/Ames Research Center 9x7-foot Supersonic Wind Tunnel to help resolve an anomaly that developed during the STS-6 orbiter flight wherein sections of the Advanced Flexible Reusable Surface Insulation (AFRSI) covering the OMS pods suffered some damage. A one-third scale two-dimensional shell structure model of an OMS pod cross-section was employed to support the test articles. These consisted of 15 AFRSI blanket panels form-fitted over the shell structures for exposure to simulated flight conditions. Of six baseline blankets, two were treated with special surface coatings. Two other panels were configured with AFRSI sections removed from the OV099 orbiter vehicle after the STS-6 flight. Seven additional specimens incorporated alternative designs and repairs. Following a series of surface pressure calibration runs, the specimens were exposed to simulated ascent and entry dynamic pressure profiles. Entry conditions included the use of a vortex generator to evaluate the effect of shed vortices on the AFRSI located in the area of concern.

  10. Differential toxicity of Disperse Red 1 and Disperse Red 13 in the Ames test, HepG2 cytotoxicity assay, and Daphnia acute toxicity test.

    Science.gov (United States)

    Ferraz, E R A; Umbuzeiro, G A; de-Almeida, G; Caloto-Oliveira, A; Chequer, F M D; Zanoni, M V B; Dorta, D J; Oliveira, D P

    2011-10-01

    Azo dyes are of environmental concern due to their degradation products, widespread use, and low-removal rate during conventional treatment. Their toxic properties are related to the nature and position of the substituents with respect to the aromatic rings and amino nitrogen atom. The dyes Disperse Red 1 and Disperse Red 13 were tested for Salmonella mutagenicity, cell viability by annexin V, and propidium iodide in HepG2 and by aquatic toxicity assays using daphnids. Both dyes tested positive in the Salmonella assay, and the suggestion was made that these compounds induce mainly frame-shift mutations and that the enzymes nitroreductase and O-acetyltransferase play an important role in the observed effect. In addition, it was shown that the presence of the chlorine substituent in Disperse Red 13 decreased the mutagenicity about 14 times when compared with Disperse Red 1, which shows the same structure as Disperse Red 13, but without the chlorine substituent. The presence of this substituent did not cause cytotoxicity in HepG2 cells, but toxicity to the water flea Daphnia similis increased in the presence of the chlorine substituent. These data suggest that the insertion of a chlorine substituent could be an alternative in the design of dyes with low-mutagenic potency, although the ecotoxicity should be carefully evaluated. PMID:20549607

  11. Ames research center publications, 1975

    Science.gov (United States)

    Sherwood, B. R. (Compiler)

    1977-01-01

    This bibliography cites 851 documents by Ames Research Center personnel and contractors which appeared in formal NASA publications, journals, books, patents, and contractor reports in 1975, or not included in previous annual bibliographies. An author index is provided.

  12. Radiological survey support activities for the decommissioning of the Ames Laboratory Research Reactor Facility, Ames, Iowa

    International Nuclear Information System (INIS)

    At the request of the Engineering Support Division of the US Department of Energy-Chicago Operations Office and in accordance with the programmatic overview/certification responsibilities of the Department of Energy Environmental and Safety Engineering Division, the Argonne National Laboratory Radiological Survey Group conducted a series of radiological measurements and tests at the Ames Laboratory Research Reactor located in Ames, Iowa. These measurements and tests were conducted during 1980 and 1981 while the reactor building was being decontaminated and decommissioned for the purpose of returning the building to general use. The results of these evaluations are included in this report. Although the surface contamination within the reactor building could presumably be reduced to negligible levels, the potential for airborne contamination from tritiated water vapor remains. This vapor emmanates from contamination within the concrete of the building and should be monitored until such time as it is reduced to background levels. 2 references, 8 figures, 6 tables

  13. Computational Methods Development at Ames

    Science.gov (United States)

    Kwak, Dochan; Smith, Charles A. (Technical Monitor)

    1998-01-01

    This viewgraph presentation outlines the development at Ames Research Center of advanced computational methods to provide appropriate fidelity computational analysis/design capabilities. Current thrusts of the Ames research include: 1) methods to enhance/accelerate viscous flow simulation procedures, and the development of hybrid/polyhedral-grid procedures for viscous flow; 2) the development of real time transonic flow simulation procedures for a production wind tunnel, and intelligent data management technology; and 3) the validation of methods and the flow physics study gives historical precedents to above research, and speculates on its future course.

  14. Management process invaded Ames as the Center shifted from NACA to NASA oversight. Ames constructed

    Science.gov (United States)

    1968-01-01

    Management process invaded Ames as the Center shifted from NACA to NASA oversight. Ames constructed a review room in its headquarters building where, in the graphical style that prevailed in the 1960's, Ames leadership could review progress against schedule, budget and performance measures. Shown, in October 1965 is Merrill Mead chief of Ames' program and resources office. (for H Julian Allen Retirement album)

  15. Environmental Survey preliminary report, Ames Laboratory, Ames, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    1989-03-01

    This report presents the preliminary findings of the first phase of the environmental Survey of the United States Department of Energy's (DOE) Ames Laboratory, conducted April 18 through 22, 1988. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team members are being supplied by private contractors. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the Ames Laboratory. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at the Ames Laboratory, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The S A plan is being developed by the Idaho National Engineering Laboratory. When S A is completed, the results will be incorporated into the Ames Laboratory Environmental Survey findings for inclusion in the Environmental Survey Summary Report. 60 refs., 13 figs., 20 tabs.

  16. NASA Ames Environmental Sustainability Report 2011

    Science.gov (United States)

    Clarke, Ann H.

    2011-01-01

    The 2011 Ames Environmental Sustainability Report is the second in a series of reports describing the steps NASA Ames Research Center has taken toward assuring environmental sustainability in NASA Ames programs, projects, and activities. The Report highlights Center contributions toward meeting the Agency-wide goals under the 2011 NASA Strategic Sustainability Performance Program.

  17. UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test

    International Nuclear Information System (INIS)

    We investigated the photo-mutagenicity and photo-genotoxicity of N-dialkylnitrosamines and its mechanisms of UVA activation. With simultaneous irradiation of UVA, photo-mutagenicity of seven N-dialkylnitrosamines was observed in Ames bacteria (Salmonella typhimurium TA1535) in the absence of metabolic activation. Mutagenicity of pre-irradiated N-dialkylnitrosamines was also observed with S. typhimurium hisG46, TA100, TA102 and YG7108 in the absence of metabolic activation. UVA-mediated mutation with N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) decreased by adding either the NO or OH radical scavenger. When superhelical DNA was irradiated with N-dialkylnitrosamines, nicked circular DNA appeared. Ten N-dialkylnitrosamines examined produced strand breaks in the treated DNA in the presence of UVA. The level of single-strand breaks in φX174 DNA mediated by N-nitrosomorpholine (NMOR) and UVA decreased by adding either a radical scavenger or superoxide dismutase. When calf thymus DNA was treated with N-dialkylnitrosamines (NDMA, NDEA, NMOR, N-nitrosopyrrolidine (NPYR) and N-nitrosopiperidine (NPIP)) and UVA, the ratio of 8-oxodG/dG in the DNA increased. Action spectra were obtained to determine if nitrosamine acts as a sensitizer of UVA. Both mutation frequency and NO formation were highest at the absorption maximum of nitrosamines, approximately 340 nm. The plots of NO formation and mutation frequency align with the absorption curve of NPYR, NMOR and NDMA. A significant linear correlation between the optical density of N-dialkynitrosamines at 340 nm and NO formation in each irradiated solution was revealed by ANOVA. We would like to propose the hypothesis that the N-nitroso moiety of N-dialkylnitrosamines absorbs UVA photons, UVA-photolysis of N-dialkylnitrosamines brings release of nitric oxide, and subsequent production of alkyl radical cations and active oxygen species follow as secondary events, which cause DNA strand breaks, oxidative and

  18. UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test

    Energy Technology Data Exchange (ETDEWEB)

    Arimoto-Kobayashi, Sakae, E-mail: arimoto@cc.okayama-u.ac.jp [Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima, Okayama 700-8530 (Japan); Sano, Kayoko; Machida, Masaki; Kaji, Keiko; Yakushi, Keiko [Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima, Okayama 700-8530 (Japan)

    2010-09-10

    We investigated the photo-mutagenicity and photo-genotoxicity of N-dialkylnitrosamines and its mechanisms of UVA activation. With simultaneous irradiation of UVA, photo-mutagenicity of seven N-dialkylnitrosamines was observed in Ames bacteria (Salmonella typhimurium TA1535) in the absence of metabolic activation. Mutagenicity of pre-irradiated N-dialkylnitrosamines was also observed with S. typhimurium hisG46, TA100, TA102 and YG7108 in the absence of metabolic activation. UVA-mediated mutation with N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) decreased by adding either the NO or OH radical scavenger. When superhelical DNA was irradiated with N-dialkylnitrosamines, nicked circular DNA appeared. Ten N-dialkylnitrosamines examined produced strand breaks in the treated DNA in the presence of UVA. The level of single-strand breaks in {phi}X174 DNA mediated by N-nitrosomorpholine (NMOR) and UVA decreased by adding either a radical scavenger or superoxide dismutase. When calf thymus DNA was treated with N-dialkylnitrosamines (NDMA, NDEA, NMOR, N-nitrosopyrrolidine (NPYR) and N-nitrosopiperidine (NPIP)) and UVA, the ratio of 8-oxodG/dG in the DNA increased. Action spectra were obtained to determine if nitrosamine acts as a sensitizer of UVA. Both mutation frequency and NO formation were highest at the absorption maximum of nitrosamines, approximately 340 nm. The plots of NO formation and mutation frequency align with the absorption curve of NPYR, NMOR and NDMA. A significant linear correlation between the optical density of N-dialkynitrosamines at 340 nm and NO formation in each irradiated solution was revealed by ANOVA. We would like to propose the hypothesis that the N-nitroso moiety of N-dialkylnitrosamines absorbs UVA photons, UVA-photolysis of N-dialkylnitrosamines brings release of nitric oxide, and subsequent production of alkyl radical cations and active oxygen species follow as secondary events, which cause DNA strand breaks, oxidative and

  19. Wind tunnel tests of the 0.010-scale space shuttle integrated vehicle (model 52-QT) in the NASA/Ames 3.5-foot hypersonic wind tunnel (IA18)

    Science.gov (United States)

    Esparza, V.; Chee, E.; Stone, J.; Mellenthin, J. A.

    1975-01-01

    Experimental aerodynamic investigations were conducted in the NASA/Ames Research Center 3.5-foot hypersonic wind tunnel on an 0.010-scale model of the space shuttle integrated vehicle consisting of an orbiter and external tank. The basic hypersonic stability characteristics of the orbiter attached rigidly to the external tank and the basic hypersonic stability characteristics of external tank alone simulating RTLS abort conditions were evaluated. The integrated vehicle was tested at angles of attack from- 8 deg through +30 deg and angles of sideslip of- 8 deg through +8 deg at fixed angles of attack of -4 deg, 0 deg, and +4 deg. A maximum angle of attack range of +15 deg through +40 deg was obtained for this configuration, at Mach number 7.3, for one run only. External tank alone testing was conducted at angles of attack from +8 deg through -30 deg and angles of sideslip of -8 deg at fixed angles of attack of -4 deg, 0 deg and +4 deg. Six-component force data and static base pressures were recorded during the test.

  20. Atmosphere of Freedom: Sixty Years at the NASA Ames Research Center

    Science.gov (United States)

    Bugos, Glenn E.; Launius, Roger (Technical Monitor)

    2000-01-01

    Throughout Ames History, four themes prevail: a commitment to hiring the best people; cutting-edge research tools; project management that gets things done faster, better and cheaper; and outstanding research efforts that serve the scientific professions and the nation. More than any other NASA Center, Ames remains shaped by its origins in the NACA (National Advisory Committee for Aeronautics). Not that its missions remain the same. Sure, Ames still houses the world's greatest collection of wind tunnels and simulation facilities, its aerodynamicists remain among the best in the world, and pilots and engineers still come for advice on how to build better aircraft. But that is increasingly part of Ames' past. Ames people have embraced two other missions for its future. First, intelligent systems and information science will help NASA use new tools in supercomputing, networking, telepresence and robotics. Second, astrobiology will explore lore the prospects for life on Earth and beyond. Both new missions leverage Ames long-standing expertise in computation and in the life sciences, as well as its relations with the computing and biotechnology firms working in the Silicon Valley community that has sprung up around the Center. Rather than the NACA missions, it is the NACA culture that still permeates Ames. The Ames way of research management privileges the scientists and engineers working in the laboratories. They work in an atmosphere of freedom, laced with the expectation of integrity and responsibility. Ames researchers are free to define their research goals and define how they contribute to the national good. They are expected to keep their fingers on the pulse of their disciplines, to be ambitious yet frugal in organizing their efforts, and to always test their theories in the laboratory or in the field. Ames' leadership ranks, traditionally, are cultivated within this scientific community. Rather than manage and supervise these researchers, Ames leadership merely

  1. NASA-Ames vertical gun

    Science.gov (United States)

    Schultz, P. H.

    1984-01-01

    A national facility, the NASA-Ames vertical gun range (AVGR) has an excellent reputation for revealing fundamental aspects of impact cratering that provide important constraints for planetary processes. The current logistics in accessing the AVGR, some of the past and ongoing experimental programs and their relevance, and the future role of this facility in planetary studies are reviewed. Publications resulting from experiments with the gun (1979 to 1984) are listed as well as the researchers and subjects studied.

  2. Ames Air Revitalization

    Science.gov (United States)

    Huang, Roger Z.

    2015-01-01

    This is an informal presentation presented to the University of Colorado, Boulder Bioastronautics group seminar. It highlights the key focal areas of the Air Revitalization Group research over the past year, including progress on the CO2 Removal and Compression System, testing of CDRA drying bed configurations, and adsorption research.

  3. Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel non-basic 1-(2H-indazole-5-yl)pyridin-2(1H)-one derivatives and mitigation of mutagenicity in Ames test.

    Science.gov (United States)

    Igawa, Hideyuki; Takahashi, Masashi; Ikoma, Minoru; Kaku, Hiromi; Kakegawa, Keiko; Kina, Asato; Aida, Jumpei; Okuda, Shoki; Kawata, Yayoi; Noguchi, Toshihiro; Hotta, Natsu; Yamamoto, Syunsuke; Nakayama, Masaharu; Nagisa, Yasutaka; Kasai, Shizuo; Maekawa, Tsuyoshi

    2016-06-01

    To develop non-basic melanin-concentrating hormone receptor 1 (MCHR1) antagonists with a high probability of target selectivity and therapeutic window, we explored neutral bicyclic motifs that could replace the previously reported imidazo[1,2-a]pyridine or 1H-benzimidazole motif. The results indicated that the binding affinity of a chemically neutral 2H-indazole derivative 8a with MCHR1 (hMCHR1: IC50=35nM) was comparable to that of the imidazopyridine and benzimidazole derivatives (1 and 2, respectively) reported so far. However, 8a was positive in the Ames test using TA1537 in S9- condition. Based on a putative intercalation of 8a with DNA, we introduced a sterically-hindering cyclopropyl group on the indazole ring to decrease planarity, which led to the discovery of 1-(2-cyclopropyl-3-methyl-2H-indazol-5-yl)-4-{[5-(trifluoromethyl)thiophen-3-yl]methoxy}pyridin-2(1H)-one 8l without mutagenicity in TA1537. Compound 8l exerted significant antiobesity effects in diet-induced obese F344 rats and exhibited promising safety profile. PMID:27117261

  4. Ames Life Science Data Archive: Translational Rodent Research at Ames

    Science.gov (United States)

    Wood, Alan E.; French, Alison J.; Ngaotheppitak, Ratana; Leung, Dorothy M.; Vargas, Roxana S.; Maese, Chris; Stewart, Helen

    2014-01-01

    The Life Science Data Archive (LSDA) office at Ames is responsible for collecting, curating, distributing and maintaining information pertaining to animal and plant experiments conducted in low earth orbit aboard various space vehicles from 1965 to present. The LSDA will soon be archiving data and tissues samples collected on the next generation of commercial vehicles; e.g., SpaceX & Cygnus Commercial Cargo Craft. To date over 375 rodent flight experiments with translational application have been archived by the Ames LSDA office. This knowledge base of fundamental research can be used to understand mechanisms that affect higher organisms in microgravity and help define additional research whose results could lead the way to closing gaps identified by the Human Research Program (HRP). This poster will highlight Ames contribution to the existing knowledge base and how the LSDA can be a resource to help answer the questions surrounding human health in long duration space exploration. In addition, it will illustrate how this body of knowledge was utilized to further our understanding of how space flight affects the human system and the ability to develop countermeasures that negate the deleterious effects of space flight. The Ames Life Sciences Data Archive (ALSDA) includes current descriptions of over 700 experiments conducted aboard the Shuttle, International Space Station (ISS), NASA/MIR, Bion/Cosmos, Gemini, Biosatellites, Apollo, Skylab, Russian Foton, and ground bed rest studies. Research areas cover Behavior and Performance, Bone and Calcium Physiology, Cardiovascular Physiology, Cell and Molecular Biology, Chronobiology, Developmental Biology, Endocrinology, Environmental Monitoring, Gastrointestinal Physiology, Hematology, Immunology, Life Support System, Metabolism and Nutrition, Microbiology, Muscle Physiology, Neurophysiology, Pharmacology, Plant Biology, Pulmonary Physiology, Radiation Biology, Renal, Fluid and Electrolyte Physiology, and Toxicology. These

  5. Results of convective heating tests of a longitudinal gap on the Rockwell flat plate model (15-0, insert 7) in the NASA/Ames Research Center

    Science.gov (United States)

    Quan, M.; Lockman, W. K.

    1975-01-01

    Results are presented which were obtained from tests in a hypersonic wind tunnel to determine aerodynamic heating rates in a gap running parallel or slightly askew to the flow direction. The model used was a flat plate instrumented in thin-skin sections with chromelconstantan thermocouples. Heating rate profiles lengthwise along and down into the gap were obtained, and additional data were obtained from a total temperature probe and rake fabricated during the test to investigate an apparent aerodynamic cooling trend in the gap. Model variables were width, depth, length, and orientation of the gap relative to the flow direction. The tests were conducted at Mach 5.1 and Reynolds numbers per foot of 500,000, 1,000,000, and 2,000,000.

  6. Briefing to University of Porto on NASA Airborne Science Program and Ames UAVs

    Science.gov (United States)

    Fladeland, Matthew

    2015-01-01

    NASA Ames is exploring a partnership with the University of Portugal to jointly develop and test new autonomous vehicle technologies. As part of the discussions I will be briefing the University of Portugal faculty on the NASA Airborne Science Program (ASP) and associated activities at NASA Ames Research Center. The presentation will communicate the requirements that drive the program, the assets available to NASA researchers, and discuss research projects that have used unmanned aircraft systems including MIZOPEX, Surprise Valley, and Florida Keys Coral Reef assessment. Other topics will include the SIERRA and Dragon Eye UAV projects operated at Ames.

  7. A. F. Ames, Village Schoolmaster. A Memoir.

    Science.gov (United States)

    Ames, Edward C.

    This booklet sketches the life, educational theories, and accomplishments of Albert F. Ames (1888-1931). Ames was trained as a mathematician, and served six years as a mathematics teacher in Canada before becoming superintendent of schools in Riverside, Illinois. He co-authored five mathematics textbooks with J. A. McLellan. These texts,…

  8. Tiger Team Assessment of the Ames Laboratory

    International Nuclear Information System (INIS)

    This report documents the Tiger Assessment of the Ames Laboratory (Ames), located in Ames, Iowa. Ames is operated for the US Department of Energy (DOE) by Iowa State University. The assessment was conducted from February 10 to March 5, 1992, under the auspices of the Office of Special Projects, Office of the Assistant Secretary of Environment, Safety and Health, Headquarters, DOE. The assessment was comprehensive, encompassing Environment, Safety, and Health (ES ampersand H) disciplines; management practices; and contractor and DOE self-assessments. Compliance with applicable Federal, State of Iowa, and local regulations; applicable DOE Orders; best management practices; and internal requirements at Ames Laboratory were assessed. In addition, an evaluation of the adequacy and effectiveness of DOE and the site contractor's management of ES ampersand H/quality assurance program was conducted

  9. Tiger Team Assessment of the Ames Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1992-03-01

    This report documents the Tiger Assessment of the Ames Laboratory (Ames), located in Ames, Iowa. Ames is operated for the US Department of Energy (DOE) by Iowa State University. The assessment was conducted from February 10 to March 5, 1992, under the auspices of the Office of Special Projects, Office of the Assistant Secretary of Environment, Safety and Health, Headquarters, DOE. The assessment was comprehensive, encompassing Environment, Safety, and Health (ES H) disciplines; management practices; and contractor and DOE self-assessments. Compliance with applicable Federal, State of Iowa, and local regulations; applicable DOE Orders; best management practices; and internal requirements at Ames Laboratory were assessed. In addition, an evaluation of the adequacy and effectiveness of DOE and the site contractor's management of ES H/quality assurance program was conducted.

  10. 75 FR 17920 - Decision To Evaluate a Petition to Designate a Class of Employees for the Ames Laboratory, Ames...

    Science.gov (United States)

    2010-04-08

    ... HUMAN SERVICES Decision To Evaluate a Petition to Designate a Class of Employees for the Ames Laboratory, Ames, IA, To Be Included in the Special Exposure Cohort AGENCY: National Institute for Occupational... employees for the Ames Laboratory, Ames, Iowa, to be included in the Special Exposure Cohort under...

  11. 76 FR 22900 - Decision To Evaluate a Petition To Designate a Class of Employees From Ames Laboratory in Ames...

    Science.gov (United States)

    2011-04-25

    ... HUMAN SERVICES Decision To Evaluate a Petition To Designate a Class of Employees From Ames Laboratory in Ames, IA, To Be Included in the Special Exposure Cohort AGENCY: National Institute for Occupational... employees from Ames Laboratory in Ames, Iowa, to be included in the Special Exposure Cohort under the...

  12. Unique life sciences research facilities at NASA Ames Research Center

    Science.gov (United States)

    Mulenburg, G. M.; Vasques, M.; Caldwell, W. F.; Tucker, J.

    1994-01-01

    The Life Science Division at NASA's Ames Research Center has a suite of specialized facilities that enable scientists to study the effects of gravity on living systems. This paper describes some of these facilities and their use in research. Seven centrifuges, each with its own unique abilities, allow testing of a variety of parameters on test subjects ranging from single cells through hardware to humans. The Vestibular Research Facility allows the study of both centrifugation and linear acceleration on animals and humans. The Biocomputation Center uses computers for 3D reconstruction of physiological systems, and interactive research tools for virtual reality modeling. Psycophysiological, cardiovascular, exercise physiology, and biomechanical studies are conducted in the 12 bed Human Research Facility and samples are analyzed in the certified Central Clinical Laboratory and other laboratories at Ames. Human bedrest, water immersion and lower body negative pressure equipment are also available to study physiological changes associated with weightlessness. These and other weightlessness models are used in specialized laboratories for the study of basic physiological mechanisms, metabolism and cell biology. Visual-motor performance, perception, and adaptation are studied using ground-based models as well as short term weightlessness experiments (parabolic flights). The unique combination of Life Science research facilities, laboratories, and equipment at Ames Research Center are described in detail in relation to their research contributions.

  13. Ames Research Center Research and Technology 2000

    Science.gov (United States)

    2002-01-01

    This report highlights the challenging work accomplished during fiscal year 2000 by Ames research scientists,engineers, and technologists. It discusses research and technologies that enable the Information Age, that expand the frontiers of knowledge for aeronautics and space, and that help to maintain U.S. leadership in aeronautics and space research and technology development. The accomplishments are grouped into four categories based on four of NASA's Strategic Enterprises: Aerospace Technology, Space Science, Biological and Physical Research, and Earth Science. The primary purpose of this report is to communicate knowledge-to inform our stakeholders, customer, and partners, and the people of the United States about the scope and diversity of Ames' mission,the nature of Ames' research and technolog) activities,and the stimulating challenges ahead. The accomplishments cited illustrate the contributions that Ames is willing to improve the quality of life for our citizens and the economic position of the United States in the world marketplace.

  14. The Ames Vertical Gun Range

    Science.gov (United States)

    Karcz, J. S.; Bowling, D.; Cornelison, C.; Parrish, A.; Perez, A.; Raiche, G.; Wiens, J.-P.

    2016-01-01

    The Ames Vertical Gun Range (AVGR) is a national facility for conducting laboratory- scale investigations of high-speed impact processes. It provides a set of light-gas, powder, and compressed gas guns capable of accelerating projectiles to speeds up to 7 km s(exp -1). The AVGR has a unique capability to vary the angle between the projectile-launch and gravity vectors between 0 and 90 deg. The target resides in a large chamber (diameter approximately 2.5 m) that can be held at vacuum or filled with an experiment-specific atmosphere. The chamber provides a number of viewing ports and feed-throughs for data, power, and fluids. Impacts are observed via high-speed digital cameras along with investigation-specific instrumentation, such as spectrometers. Use of the range is available via grant proposals through any Planetary Science Research Program element of the NASA Research Opportunities in Space and Earth Sciences (ROSES) calls. Exploratory experiments (one to two days) are additionally possible in order to develop a new proposal.

  15. Results of a M = 5.3 heat transfer test of the integrated vehicle using phase-change paint techniques on the 0.0175-scale model 56-OTS in the NASA/Ames Research Center 3.5-foot hypersonic wind tunnel

    Science.gov (United States)

    Marroquin, J.

    1985-01-01

    An experimental investigation was performed in the NASA/Ames Research Center 3.5-foot Hypersonic Wind Tunnel to obtain supersonic heat-distribution data in areas between the orbiter and external tank using phase-change paint techniques. The tests used Novamide SSV Model 56-OTS in the first and second-stage ascent configurations. Data were obtained at a nominal Mach number of 5.3 and a Reynolds number per foot of 5 x 10 to the 6th power with angles of attack of 0 deg, +/- 5 deg, and sideslip angles of 0 deg and +/- 5 deg.

  16. Ames Laboratory Site Environmental Report, Calendar year 1991

    International Nuclear Information System (INIS)

    The summarized data and conclusions from the Ames Laboratory environmental monitoring program are presented in this Annual Site Environmental Report. This program is a working requirement of Department of Energy (DOE) Order 5484.1, ''Environmental Protection, Safety, and Health Protection Information Reporting Requirements'' and Order 5400.1, ''General Environmental Protection Program.'' Ames Laboratory is located on the campus of Iowa State University (ISU) and occupies several buildings owned by the DOE. The Laboratory also leases space in ISU-owned buildings. Laboratory research activities involve less than ten percent of the total chemical use and one percent of the radioisotope use on the ISU campus. Ames Laboratory is responsible for a small chemical burial site, located on ISU property. The site was used for the disposal of chemical and metal slags from thorium and uranium production. Samples of water from existing test wells and upstream and downstream sites on the nearby Squaw Creek show no detectable migration of the contents of the burial site. A Site Assessment plan submitted to the State of Iowa Department of Natural Resources (DNR) was approved. A Remedial Investigation/Feasibility Study work plan has been completed for additional studies at the site. This has been reviewed and approved by the DOE Chicago Field Office and the DNR. A National Environmental Policy Act (NEPA) review of the site resulted in a categorical exclusion finding which has been approved by the DOE. Ames Laboratory has an area contaminated by diesel fuel at the location of a storage tank which was removed in 1970. Soil corings and groundwater have been analyzed for contamination and an assessment written. Pollution awareness and waste minimization programs and plans were implemented in 1990. Included in this effort was the implementation of a waste white paper and green computer paper recycling program

  17. Results of an investigation of the acoustic and vibrational environment of a full scale space shuttle orbiter structural test panel with simulated TPS in the Ames unitary plan wind tunnel, model 81-0, test OS8A and B

    Science.gov (United States)

    Kingsland, R. B.

    1977-01-01

    Results of tests OS8A and B and pertinent test and model information are presented. The test was conducted in two parts. Test OS8A was performed in the NASA/ARC unitary 11-foot section and OS8B was conducted in the NASA/ARC unitary 9 x 7 tunnel. Test objectives were to investigate thermal protection system (TPS) tile sensitivity to extreme pressure gradients and vibration and to define the TPS aerodynamic environment. The model utilized for OS8 was a full-scale representation of a portion of the space shuttle orbiter lower wing carry-through structure forward of the aft tank strut and propellant lines. Thermal protection tiles were simulated on the model. The model was instrumented with static pressure orifices, accelerometers, and dynamic pressure transducers (Kulites). A total rake was utilized to obtain boundary layer surveys.

  18. Post-test data report for the space shuttle full-scale AFRSI sequence of environments test (OS-305-1 to -5) in the NASA/Ames Research Center 11x11-foot wind tunnel

    Science.gov (United States)

    Marshall, B. A.

    1984-01-01

    The Advanced Flexible Reusable Surface Insulation (AFRSI) test article was wind tunnel tested. The AFRSI was exposed to a simulated ascent airloads environment and data was obtained which could be used to support the AFRSI certification program. The AFRSI sequence of environments also included radiant heating (1500 degrees Fahrenheit) and wind/rain environments. The test article was wind/rain conditioned before each wind tunnel entry and was thermally conditioned after each wind tunnel entry. The AFRSI failed and the test was aborted before reaching the ascent environment. The AFRSI test article sequentially exposed to 50 wind/rain and 49 simulated entry thermal missions, as well as four wind tunnel entries equivalent to 40 ascent missions.

  19. Groundwater hydrology study of the Ames Chemical Disposal Site

    International Nuclear Information System (INIS)

    The Ames Laboratory Chemical Disposal Site is located in northwestern Ames, Iowa west of Squaw Creek. From 1957 to 1966, Ames Laboratory conducted research to develop processes to separate uranium and thorium from nuclear power fuel and to separate yttrium from neutron shielding sources. The wastes from these processes, which contained both hazardous and radiological components, were placed into nine burial pits. Metal drums, plywood boxes, and steel pails were used to store the wastes. Uranium was also burned on the ground surface of the site. Monitoring wells were placed around the waste burial pits. Groundwater testing in 1993 revealed elevated levels of Uranium 234, Uranium 238, beta and alpha radiation. The north side of the burial pit had elevated levels of volatile organic compounds. Samples in the East Ravine showed no volatile organics; however, they did contain elevated levels of radionuclides. These analytical results seem to indicate that the groundwater from the burial pit is flowing down hill and causing contamination in the East Ravine. Although there are many avenues for the contamination to spread, the focus of this project is to understand the hydrogeology of the East Ravine and to determine the path of groundwater flow down the East Ravine. The groundwater flow data along with other existing information will be used to assess the threat of chemical migration down the East Ravine and eventually off-site. The primary objectives of the project were as follows: define the geology of the East Ravine; conduct slug tests to determine the hydraulic conductivity of both oxidized and unoxidized till; develop a three-dimensional mathematical model using ModIME and MODFLOW to simulate groundwater flow in the East Ravine

  20. AIM: Ames Imaging Module Spacecraft Camera

    Science.gov (United States)

    Thompson, Sarah

    2015-01-01

    The AIM camera is a small, lightweight, low power, low cost imaging system developed at NASA Ames. Though it has imaging capabilities similar to those of $1M plus spacecraft cameras, it does so on a fraction of the mass, power and cost budget.

  1. NASA Ames Fluid Mechanics Laboratory research briefs

    Science.gov (United States)

    Davis, Sanford (Editor)

    1994-01-01

    The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

  2. An aerial radiological survey of the Ames Laboratory and surrounding area, Ames, Iowa

    International Nuclear Information System (INIS)

    An aerial radiological survey of the Ames Laboratory and surrounding area in Ames, Iowa, was conducted during the period July 15--25, 1991. The purpose of the survey was to measure and document the terrestrial radiological environment at the Ames Laboratory and the surrounding area for use in effective environmental management and emergency response planning. The aerial survey was flown at an altitude of 200 feet (61 meters) along a series of parallel lines 350 feet (107 meters) apart. The survey encompassed an area of 36 square miles (93 square kilometers) and included the city of Ames, Iowa, and the Iowa State University. The results are reported as exposure rates at 1 meter above ground level (inferred from the aerial data) in the form of a gamma radiation contour map. Typical background exposure rates were found to vary from 7 to 9 microroentgens per hour (μR/h). No anomalous radiation levels were detected at the Ames Laboratory. However, one anomalous radiation source was detected at an industrial storage yard in the city of Ames. In support of the aerial survey, ground-based exposure rate and soil sample measurements were obtained at several sites within the survey perimeter. The results of the aerial and ground-based measurements were found to agree within the expected uncertainty of ±15%

  3. Microbiology and potential applications of aerobic methane oxidation coupled to denitrification (AME-D) process: A review.

    Science.gov (United States)

    Zhu, Jing; Wang, Qian; Yuan, Mengdong; Tan, Giin-Yu Amy; Sun, Faqian; Wang, Cheng; Wu, Weixiang; Lee, Po-Heng

    2016-03-01

    Aerobic methane oxidation coupled to denitrification (AME-D) is an important link between the global methane and nitrogen cycles. This mini-review updates discoveries regarding aerobic methanotrophs and denitrifiers, as a prelude to spotlight the microbial mechanism and the potential applications of AME-D. Until recently, AME-D was thought to be accomplished by a microbial consortium where denitrifying bacteria utilize carbon intermediates, which are excreted by aerobic methanotrophs, as energy and carbon sources. Potential carbon intermediates include methanol, citrate and acetate. This mini-review presents microbial thermodynamic estimations and postulates that methanol is the ideal electron donor for denitrification, and may serve as a trophic link between methanotrophic bacteria and denitrifiers. More excitingly, new discoveries have revealed that AME-D is not only confined to the conventional synergism between methanotrophic bacteria and denitrifiers. Specifically, an obligate aerobic methanotrophic bacterium, Methylomonas denitrificans FJG1, has been demonstrated to couple partial denitrification with methane oxidation, under hypoxia conditions, releasing nitrous oxide as a terminal product. This finding not only substantially advances the understanding of AME-D mechanism, but also implies an important but unknown role of aerobic methanotrophs in global climate change through their influence on both the methane and nitrogen cycles in ecosystems. Hence, further investigation on AME-D microbiology and mechanism is essential to better understand global climate issues and to develop niche biotechnological solutions. This mini-review also presents traditional microbial techniques, such as pure cultivation and stable isotope probing, and powerful microbial techniques, such as (meta-) genomics and (meta-) transcriptomics, for deciphering linked methane oxidation and denitrification. Although AME-D has immense potential for nitrogen removal from wastewater, drinking

  4. Static and wind tunnel near-field/far-field jet noise measurements from model scale single-flow base line and suppressor nozzles. Summary report. [conducted in the Boeing large anechoic test chamber and the NASA-Ames 40by 80-foot wind tunnel

    Science.gov (United States)

    Jaeck, C. L.

    1977-01-01

    A test program was conducted in the Boeing large anechoic test chamber and the NASA-Ames 40- by 80-foot wind tunnel to study the near- and far-field jet noise characteristics of six baseline and suppressor nozzles. Static and wind-on noise source locations were determined. A technique for extrapolating near field jet noise measurements into the far field was established. It was determined if flight effects measured in the near field are the same as those in the far field. The flight effects on the jet noise levels of the baseline and suppressor nozzles were determined. Test models included a 15.24-cm round convergent nozzle, an annular nozzle with and without ejector, a 20-lobe nozzle with and without ejector, and a 57-tube nozzle with lined ejector. The static free-field test in the anechoic chamber covered nozzle pressure ratios from 1.44 to 2.25 and jet velocities from 412 to 594 m/s at a total temperature of 844 K. The wind tunnel flight effects test repeated these nozzle test conditions with ambient velocities of 0 to 92 m/s.

  5. Ames vision group research overview

    Science.gov (United States)

    Watson, Andrew B.

    1990-01-01

    A major goal of the reseach group is to develop mathematical and computational models of early human vision. These models are valuable in the prediction of human performance, in the design of visual coding schemes and displays, and in robotic vision. To date researchers have models of retinal sampling, spatial processing in visual cortex, contrast sensitivity, and motion processing. Based on their models of early human vision, researchers developed several schemes for efficient coding and compression of monochrome and color images. These are pyramid schemes that decompose the image into features that vary in location, size, orientation, and phase. To determine the perceptual fidelity of these codes, researchers developed novel human testing methods that have received considerable attention in the research community. Researchers constructed models of human visual motion processing based on physiological and psychophysical data, and have tested these models through simulation and human experiments. They also explored the application of these biological algorithms to applications in automated guidance of rotorcraft and autonomous landing of spacecraft. Researchers developed networks for inhomogeneous image sampling, for pyramid coding of images, for automatic geometrical correction of disordered samples, and for removal of motion artifacts from unstable cameras.

  6. Satellite communications provisions on NASA Ames instrumented aircraft platforms for Earth science research/applications

    Science.gov (United States)

    Shameson, L.; Brass, J. A.; Hanratty, J. J.; Roberts, A. C.; Wegener, S. S.

    1995-01-01

    Earth science activities at NASA Ames are research in atmospheric and ecosystem science, development of remote sensing and in situ sampling instruments, and their integration into scientific research platform aircraft. The use of satellite communications can greatly extend the capability of these agency research platform aircraft. Current projects and plans involve satellite links on the Perseus UAV and the ER-2 via TDRSS and a proposed experiment on the NASA Advanced Communications Technology Satellite. Provisions for data links on the Perseus research platform, via TDRSS S-band multiple access service, have been developed and are being tested. Test flights at Dryden are planned to demonstrate successful end-to-end data transfer. A Unisys Corp. airborne satcom STARLink system is being integrated into an Ames ER-2 aircraft. This equipment will support multiple data rates up to 43 Mb/s each via the TDRS S Ku-band single access service. The first flight mission for this high-rate link is planned for August 1995. Ames and JPL have proposed an ACTS experiment to use real-time satellite communications to improve wildfire research campaigns. Researchers and fire management teams making use of instrumented aircraft platforms at a prescribed burn site will be able to communicate with experts at Ames, the U.S. Forest Service, and emergency response agencies.

  7. Semantic Web Infrastructure Supporting NextFrAMES Modeling Platform

    Science.gov (United States)

    Lakhankar, T.; Fekete, B. M.; Vörösmarty, C. J.

    2008-12-01

    from observation to the delivery of highly aggregated information. Our presentation will discuss the web services ranging from OpenDAP and WaterOneFlow data services to metadata provided through catalog services that could serve NextFrAMES modeling applications. We will also discuss the support infrastructure needed to streamline the integration of NextFrAMES into an End-to-End application to deliver highly processed information to end users. The End-to-End application will be demonstrated through examples from the State-of-the Global Water System effort that builds on data services provided through WMO's Global Terrestrial Network for Hydrology to deliver water resources related information to policy makers for better water management. Key components of this E2E system are promoted as Community of Practice examples for the Global Observing System of Systems therefore the State-of-the Global Water System can be viewed as test case for the interoperability of the incorporated web service components.

  8. Air Traffic Management Research at NASA Ames

    Science.gov (United States)

    Davis, Thomas J.

    2012-01-01

    The Aviation Systems Division at the NASA Ames Research Center conducts leading edge research in air traffic management concepts and technologies. This overview will present concepts and simulation results for research in traffic flow management, safe and efficient airport surface operations, super density terminal area operations, separation assurance and system wide modeling and simulation. A brief review of the ongoing air traffic management technology demonstration (ATD-1) will also be presented. A panel discussion, with Mr. Davis serving as a panelist, on air traffic research will follow the briefing.

  9. Experimental program for real gas flow code validation at NASA Ames Research Center

    Science.gov (United States)

    Deiwert, George S.; Strawa, Anthony W.; Sharma, Surendra P.; Park, Chul

    1989-01-01

    The experimental program for validating real gas hypersonic flow codes at NASA Ames Rsearch Center is described. Ground-based test facilities used include ballistic ranges, shock tubes and shock tunnels, arc jet facilities and heated-air hypersonic wind tunnels. Also included are large-scale computer systems for kinetic theory simulations and benchmark code solutions. Flight tests consist of the Aeroassist Flight Experiment, the Space Shuttle, Project Fire 2, and planetary probes such as Galileo, Pioneer Venus, and PAET.

  10. Diverse Studies in the Reactivated NASA/Ames Radiation Facility: From Shock Layer Spectroscopy to Thermal Protection System Impact

    Science.gov (United States)

    Miller, Robert J.; Hartman, G. Joseph (Technical Monitor)

    1994-01-01

    NASA/Ames' Hypervelocity Free-Flight Radiation Facility has been reactivated after having been decommissioned for some 15 years, first tests beginning in early 1994. This paper discusses two widely different studies from the first series, one involving spectroscopic analysis of model shock-layer radiation, and the other the production of representative impact damage in space shuttle thermal protection tiles for testing in the Ames arc-jet facilities. These studies emphasize the interorganizational and interdisciplinary value of the facility in the newly-developing structure of NASA.

  11. Studies of Anomalous Microwave Emission (AME) with the SKA

    CERN Document Server

    Dickinson, Clive; Beswick, Robert J; Casassus, Simon; Cleary, Kieran; Draine, Bruce T; Genova-Santos, Ricardo; Grainge, Keith; Hoang, Thiem C; Lazarian, Alex; Murphy, Eric J; Paladini, Roberta; Peel, Michael W; Perrott, Yvette; Rubino-Martin, Jose-Alberto; Scaife, Anna; Tibbs, Chris T; Verstraete, Laurent; Vidal, Matias; Watson, Robert A; Ysard, Nathalie

    2014-01-01

    In this chapter, we will outline the scientific motivation for studying Anomalous Microwave Emission (AME) with the SKA. AME is thought to be due to electric dipole radiation from small spinning dust grains, although thermal fluctuations of magnetic dust grains may also contribute. Studies of this mysterious component would shed light on the emission mechanism, which then opens up a new window onto the interstellar medium (ISM). AME is emitted mostly in the frequency range $\\sim 10$--100\\,GHz, and thus the SKA has the potential of measuring the low frequency side of the AME spectrum, particularly in band 5. Science targets include dense molecular clouds in the Milky Way, as well as extragalactic sources. We also discuss the possibility of detecting rotational line emission from Poly-cyclic Aromatic Hydrocarbons (PAHs), which could be the main carriers of AME. Detecting PAH lines of a given spacing would allow for a definitive identification of specific PAH species.

  12. Results of the AFRSI detailed-environment test of the 0.035-scale SSV pressure-loads model 84-0 in the Ames 11x11 ft. TWT and the Lewis 8x6 ft. and 10x10 ft. SWT (OA-310A, B, C), volume 1

    Science.gov (United States)

    Marshall, B. A.; Marroquin, J.

    1984-01-01

    Detailed orbiter aerodynamic and aeroacoustic pressure data were obtained in a three-part experimental investigation (OA-310A, B and C). The tests were conducted in three NASA facilities: OA-310A in the Ames 11x11-foot Transonic Wind Tunnel; OA-310B in the Lewis 8x6-foot Supersonic Wind Tunnel; and OA-310C in the Lewis 10x10-foot Supersonic Wind Tunnel. Test data were obtained to support analysis of the Space Transportation System (STS)-6 advanced flexible reusable surface insulation (AFRSI) anomaly using the 0.035-scale space shuttle vehicle pressure-loads Model 84-0. Data were obtained in the areas of the orbiter where AFRSI is to be applied to OV-099 and OV-103. Emphasis was placed on acquiring detailed aeroacoustic data and time-averaged pressure distributions on five affected areas: (1) canopy; (2) side of fuselage; (3) upper surface of wing; (4) OMS pods; and (5) vertical tail. Data were obtained at nominal ascent and entry atmospheric flight trajectory conditions between M=0.6 through M-3.5. Sample plotted data are given. aba M.G.

  13. Results of a FRSI material test under Space Shuttle ascent conditions in the Ames Research Center 9x7 foot supersonic wind tunnel (OS13). Space Shuttle aerothermodynamic data report

    Science.gov (United States)

    Lemoine, P. L.; Collette, J. G. R.

    1992-01-01

    A test was conducted in the NASA/ARC 9 x 7 foot supersonic wind tunnel to verify the integrity of Felt Reusable Surface Insulation (FRSI) material in a panel flutter environment. A FRSI sample panel was subjected to the shocks, pressure gradients, and turbulence characteristics encountered at dynamic pressure 1.5 times the 3(sigma) dispersed trajectory flight conditions of the Space Shuttle. Static and fluctuating pressure data were obtained for Mach numbers ranging from 1.55 to 2.5 with dynamic pressures of 625 to 1250 psf. The FRSI panel suffered no appreciable damage as a result of the test.

  14. Consolidated Laser-Induced Fluorescence Diagnostic Systems for the NASA Ames Arc Jet Facilities

    Science.gov (United States)

    Grinstead, Jay H.; Wilder, Michael C.; Porter, Barry J.; Brown, Jeffrey D.; Yeung, Dickson; Battazzo, Stephen J.; Brubaker, Timothy R.

    2016-01-01

    The spectroscopic diagnostic technique of two photon absorption laser-induced fluorescence (TALIF) of atomic species for non-intrusive arc jet flow property measurement was first implemented at NASA Ames in the mid-1990s. Use of TALIF expanded at NASA Ames and to NASA Johnson's arc jet facility in the late 2000s. In 2013-2014, NASA combined the agency's large-scale arc jet test capabilities at NASA Ames. Concurrent with that effort, the agency also sponsored a project to establish two comprehensive LIF diagnostic systems for the Aerodynamic Heating Facility (AHF) and Interaction Heating Facility (IHF) arc jets. The scope of the project enabled further engineering development of the existing IHF LIF system as well as the complete reconstruction of the original AHF LIF system. The updated LIF systems are identical in design and capability. They represent the culmination of over 20 years of development experience in transitioning a specialized laboratory research tool into a measurement system for large-scale, high-demand test facilities. This paper documents the overall system design from measurement requirements to implementation. Representative data from the redeveloped AHF and IHF LIF systems are also presented.

  15. AMES: Towards an Agile Method for ERP Selection

    OpenAIRE

    Juell-Skielse, Gustaf; Nilsson, Anders G.; Nordqvist, Andreas; Westergren, Mattias

    2012-01-01

    Conventional on-premise installations of ERP are now rapidly being replaced by ERP as service. Although ERP becomes more accessible and no longer requires local infrastructure, current selection methods do not take full advantage of the provided agility. In this paper we present AMES (Agile Method for ERP Selection), a novel method for ERP selection which better utilizes the strengths of service oriented ERP. AMES is designed to shorten lead time for selection, support identification of essen...

  16. Reaching for the APEX at Ames

    Science.gov (United States)

    Kohut, Matthew

    2008-01-01

    The multidimensional design of the APEX program is the result of an extensive research and development effort dating back nearly a decade. "In the late 1990s and early 2000, we were pretty successful at getting new research and technology projects here at the center," Johnson says, "and we had a lack of critical mass of project managers. We were taking people who were primarily researchers and putting them in the position of managing projects." Smith and Johnson held a series of workshops across the center during 2000 and 2001 to gather feedback about how to address this issue. When they briefed the center's senior management on their findings, one of the top recommendations was to establish a project manager development program at Ames. At that point, they cast a wide net for ideas and information. "We did centerwide needs assessment, we did focus groups, we did surveys," Smith says. "We came up with a proposal for what a program would look like, tying in what we knew about the Academy of Program1 Project Leadership (now the Academy for Program/Project and Engineering Leadership, or APPEL), what we've seen at other centers, what other centers have tried. We were always checking to make sure our program mapped to APPEL. We also looked at the PMI [Project Management Institute] model, INCOSE [International Council on Systems Engineering], CMMI [Capability Maturity Model Integration], you name it." "We had a lot of conversations with the Jet Propulsion Lab and Goddard," Johnson adds. "We saw those centers as models for what Ames was aspiring to be in terms of a center for managing space flight missions." Their research confirmed what they already knew-that strong practitioner involvement would be critical to their program design process. 'XPEX is for the practitioner by the practitioner," Smith says. "They have to be a part of designing it. Otherwise there's no way we could design a program that meets their needs." At the same time that they worked at the grassroots

  17. Ames life science telescience testbed evaluation

    Science.gov (United States)

    Haines, Richard F.; Johnson, Vicki; Vogelsong, Kristofer H.; Froloff, Walt

    1989-01-01

    Eight surrogate spaceflight mission specialists participated in a real-time evaluation of remote coaching using the Ames Life Science Telescience Testbed facility. This facility consisted of three remotely located nodes: (1) a prototype Space Station glovebox; (2) a ground control station; and (3) a principal investigator's (PI) work area. The major objective of this project was to evaluate the effectiveness of telescience techniques and hardware to support three realistic remote coaching science procedures: plant seed germinator charging, plant sample acquisition and preservation, and remote plant observation with ground coaching. Each scenario was performed by a subject acting as flight mission specialist, interacting with a payload operations manager and a principal investigator expert. All three groups were physically isolated from each other yet linked by duplex audio and color video communication channels and networked computer workstations. Workload ratings were made by the flight and ground crewpersons immediately after completing their assigned tasks. Time to complete each scientific procedural step was recorded automatically. Two expert observers also made performance ratings and various error assessments. The results are presented and discussed.

  18. NASA Ames UV-LED Poster Overview

    Science.gov (United States)

    Jaroux, Belgacem Amar

    2015-01-01

    UV-LED is a small satellite technology demonstration payload being flown on the Saudisat-4 spacecraft that is demonstrating non-contacting charge control of an isolated or floating mass using new solid-state ultra-violet light emitting diodes (UV-LEDs). Integrated to the rest of the spacecraft and launched on a Dnepr in June 19, 2014, the project is a collaboration between the NASA Ames Research Center (ARC), Stanford University, and King Abdulaziz City for Science and Technology (KACST). Beginning with its commissioning in December, 2015, the data collected by UV-LED have validated a novel method of charge control that will improve the performance of drag-free spacecraft allowing for concurrent science collection during charge management operations as well as reduce the mass, power and volume required while increasing lifetime and reliability of a charge management subsystem. UV-LED continues to operate, exploring new concepts in non-contacting charge control and collecting data crucial to understanding the lifetime of ultra-violet light emitting diodes in space. These improvements are crucial to the success of ground breaking missions such as LISA and BBO, and demonstrates the ability of low cost small satellite missions to provide technological advances that far exceed mission costs.

  19. Recent Developments in Ultra High Temperature Ceramics at NASA Ames

    Science.gov (United States)

    Johnson, Sylvia M.; Gasch, Matt; Lawson, John W.; Gusman, Michael I.; Stackpole, Margaret M.

    2009-01-01

    NASA Ames is pursuing a variety of approaches to modify and control the microstructure of UHTCs with the goal of improving fracture toughness, oxidation resistance and controlling thermal conductivity. The overall goal is to produce materials that can perform reliably as sharp leading edges or nose tips in hypersonic reentry vehicles. Processing approaches include the use of preceramic polymers as the SiC source (as opposed to powder techniques), the addition of third phases to control grain growth and oxidation, and the use of processing techniques to produce high purity materials. Both hot pressing and field assisted sintering have been used to make UHTCs. Characterization of the mechanical and thermal properties of these materials is ongoing, as is arcjet testing to evaluate performance under simulated reentry conditions. The preceramic polymer approach has generated a microstructure in which elongated SiC grains grow in the form of an in-situ composite. This microstructure has the advantage of improving fracture toughness while potentially improving oxidation resistance by reducing the amount and interconnectivity of SiC in the material. Addition of third phases, such as Ir, results in a very fine-grained microstructure, even in hot-pressed samples. The results of processing and compositional changes on microstructure and properties are reported, along with selected arcjet results.

  20. Recent Progress in Entry Radiation Measurements in the NASA Ames Electric ARC Shock Tube Facility

    Science.gov (United States)

    Cruden, Brett A.

    2012-01-01

    The Electric Arc Shock Tube (EAST) at NASA Ames Research Center is NASA's only working shock tube capable of obtaining conditions representative of entry in a multitude of planetary atmospheres. The facility is capable of mapping spectroscopic signatures of a wide range of planetary entries from the Vacuum Ultraviolet through Mid-Wave Infrared (120-5500 nm). This paper summarizes the tests performed in EAST for Earth, Mars and Venus entries since 2008, then focuses on a specific test case for CO2/N2 mixtures. In particular, the paper will focus on providing information for the proper interpretation of the EAST data.

  1. The ames network and the task group on WWER's

    International Nuclear Information System (INIS)

    The European Network on 'Ageing Materials Evaluation and Studies' (AMES) was created in 1993. Its main objectives are (a) to provide information and understanding on neutron irradiation effects in reactor materials in support of designers, operators, regulators and researchers and (b) to establish and discharge projects in the above areas. The Steering Committee is composed of at least one participant from each nuclear European Union country. The JRC's Institute for Advanced Materials of the European Commission plays the role of Operating Agent and Manager of the AMES Network. This paper describes the structure, objectives, and major projects of the AMES network. Particular emphasis is placed upon the work it is intended to perform within the Task Group on 'WWER's of the first AMES project (AMES1) on 'Validation of surveillance practice and mitigation methods'. EC DGXVII is addressing the question of how to facilitate contacts between EU and Russian industries in the framework of nuclear Industrial co-operation, and this project may provide a suitable starting point upon which to develop a basis for further work of mutual interest. (author)

  2. Wind Tunnel Testing Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — NASA Ames Research Center is pleased to offer the services of our premier wind tunnel facilities that have a broad range of proven testing capabilities to customers...

  3. NASA Ames Research Center R and D Services Directorate Biomedical Systems Development

    Science.gov (United States)

    Pollitt, J.; Flynn, K.

    1999-01-01

    The Ames Research Center R&D Services Directorate teams with NASA, other government agencies and/or industry investigators for the development, design, fabrication, manufacturing and qualification testing of space-flight and ground-based experiment hardware for biomedical and general aerospace applications. In recent years, biomedical research hardware and software has been developed to support space-flight and ground-based experiment needs including the E 132 Biotelemetry system for the Research Animal Holding Facility (RAHF), E 100 Neurolab neuro-vestibular investigation systems, the Autogenic Feedback Systems, and the Standard Interface Glove Box (SIGB) experiment workstation module. Centrifuges, motion simulators, habitat design, environmental control systems, and other unique experiment modules and fixtures have also been developed. A discussion of engineered systems and capabilities will be provided to promote understanding of possibilities for future system designs in biomedical applications. In addition, an overview of existing engineered products will be shown. Examples of hardware and literature that demonstrate the organization's capabilities will be displayed. The Ames Research Center R&D Services Directorate is available to support the development of new hardware and software systems or adaptation of existing systems to meet the needs of academic, commercial/industrial, and government research requirements. The Ames R&D Services Directorate can provide specialized support for: System concept definition and feasibility Mathematical modeling and simulation of system performance Prototype hardware development Hardware and software design Data acquisition systems Graphical user interface development Motion control design Hardware fabrication and high-fidelity machining Composite materials development and application design Electronic/electrical system design and fabrication System performance verification testing and qualification.

  4. Ames Selective Dissemination of Information (SDI) System Operating Manual.

    Science.gov (United States)

    Anderson, Lloyd E.; Wegner, Waldo W.

    The Ames Selective Dissemination of Information (SDI) System is an attempt to efficiently place rapidly increasing amounts of information into the hands of scientists and engineers who can exploit it. It is a computerized current awareness system designed to increase researchers' literature searching capabilities by bringing to their attention…

  5. Supersonic Retropropulsion Experimental Results from the NASA Ames 9- x 7-Foot Supersonic Wind Tunnel

    Science.gov (United States)

    Berry, Scott A.; Rhode, Matthew N.; Edquist, Karl T.

    2012-01-01

    Supersonic retropropulsion was experimentally examined in the Ames Research Center 9x7-Foot Supersonic Wind Tunnel at Mach 1.8 and 2.4. The experimental model, previously designed for and tested in the Langley Research Center Unitary Plan Wind Tunnel at Mach 2.4, 3.5 and 4.6, was a 5-in diameter 70-deg sphere-cone forebody with a 9.55-in long cylindrical aftbody. The forebody was designed to accommodate up to four 4:1 area ratio nozzles, one on the model centerline and the other three on the half radius spaced 120-deg apart. Surface pressure and flow visualization were the primary measurements, including high-speed data to investigate the dynamics of the interactions between the bow and nozzle shocks. Three blowing configurations were tested with thrust coefficients up to 10 and angles of attack up to 20-deg. Preliminary results and observations from the test are provided

  6. Ames Laboratory annual site environmental report, calendar year 1996

    International Nuclear Information System (INIS)

    This report summarizes the environmental status of Ames Laboratory for calendar year 1996. It includes descriptions of the Laboratory site, its mission, the status of its compliance with applicable environmental regulations, its planning and activities to maintain compliance, and a comprehensive review of its environmental protection, surveillance and monitoring programs. Ames Laboratory is located on the campus of Iowa State University (ISU) and occupies twelve buildings owned by the Department of Energy (DOE). The Laboratory also leases space in ISU owned buildings. Laboratory activities involve less than ten percent of the total chemical use and approximately one percent of the radioisotope use on the ISU campus. In 1996, the Office of Assurance and Assessment merged with the Environment, Safety and Health Group forming the Environment, Safety, Health and Assurance (ESH and A) office. In 1996, the Laboratory accumulated and disposed of wastes under US Environmental Protection Agency (EPA) issued generator numbers. Ames Laboratory submitted a Proposed Site Treatment Plan to EPA in December 1995. This plan complied with the Federal Facilities Compliance Act (FFCA). It was approved by EPA in January 1996. The consent agreement/consent order was issued in February 1996. Pollution awareness, waste minimization and recycling programs, implemented in 1990 and updated in 1994, continued through 1996. Included in these efforts were a waste white paper and green computer paper recycling program. Ames Laboratory also continued to recycle salvageable metal and used oil, and it recovered freon for recycling. All of the chemical and nearly all of the radiological legacy wastes were properly disposed by the end of 1996. Additional radiological legacy waste will be properly disposed during 1997

  7. NASA Ames and Future of Space Exploration, Science, and Aeronautics

    Science.gov (United States)

    Cohen, Jacob

    2015-01-01

    Pushing the frontiers of aeronautics and space exploration presents multiple challenges. NASA Ames Research Center is at the forefront of tackling these issues, conducting cutting edge research in the fields of air traffic management, entry systems, advanced information technology, intelligent human and robotic systems, astrobiology, aeronautics, space, earth and life sciences and small satellites. Knowledge gained from this research helps ensure the success of NASA's missions, leading us closer to a world that was only imagined as science fiction just decades ago.

  8. Ames Coronagraph Experiment: Enabling Missions to Directly Image Exoplanets

    Science.gov (United States)

    Belikov, Ruslan

    2014-01-01

    Technology to find biomarkers and life on other worlds is rapidly maturing. If there is a habitable planet around the nearest star, we may be able to detect it this decade with a small satellite mission. In the 2030 decade, we will likely know if there is life in our Galactic neighborhood (1000 nearest stars). The Ames Coronagraph Experiment is developing coronagraphic technologies to enable such missions.

  9. Is the Moon Illusion a Celestial Ames Demonstration?

    Science.gov (United States)

    Brecher, Kenneth

    2010-01-01

    To most naked eye observers, the Moon appears larger when seen near the horizon than it does when seen near the zenith. This "Moon Illusion” has been reported from as early as the fourth century BC and has been the subject of hundreds of papers and two books. Its explanation does not lie in the realm of physics (atmospheric refraction) or astronomy (eccentric lunar orbit) but, rather, in the realm of visual perception. Theories for the cause of the effect abound but, at present, there is no universally accepted explanation. Because the effect can be easily observed in many locations and during the course of an academic year, the moon illusion can provide a nice astronomical example that involves both direct observations and theoretical analysis. As part of the NSF funded "Project LITE: Light Inquiry Through Experiments", we have been developing inexpensive experiments and demonstrations that can be done at home. One of these is a miniature version of the classic "Ames Room". The life size version was originally developed by Adelbert Ames, Jr. and can be seen in many science museums. Our "digital” Ames Room has been designed to be printed on heavy paper using an inexpensive inkjet printer from a PDF file that is posted on the Project LITE web site http://lite.bu.edu and then cut and folded to make the room. When viewed through one wall using a commonly available door viewer, it dramatically demonstrates how the eye and brain system assesses the relative size of objects by making comparisons with the surrounding environment in which the objects are placed. In this presentation we will discuss some insights that the Ames Room provides that may offer clues to the correct explanation for the Moon Illusion. Project LITE is supported by the NSF through DUE Grant # 0715975.

  10. The AMES network strategy developments within and outside the EU

    International Nuclear Information System (INIS)

    The AMES (Ageing Materials Evaluation and Studies) network started its activity in 1993 with the aim of studying the consequences and the mechanisms of the ageing process in materials used for nuclear reactor components. Together with ENIQ, NESC, EPERC, it forms the so-called ''Structural Integrity of Industrial Components'' cluster of networks operated by the Joint Research Centre - Institute for Advanced Materials of the European Commission. After two initial phases dedicated to the compilation of state-of-the-art reports on non-destructive monitoring techniques for thermal ageing, dosimetry, survey of regulatory requirements, predictive formulas for irradiation embrittlement, AMES has entered its third strategy phase with the fifth EURATOM Framework Program, Nuclear Fission Safety Key Action. Most of the projects proposed for this program and sustained by the Steering committee were selected for funding. Their focus is on the influence of chemical composition, namely phosphorus and nickel content, on the irradiation embrittlement of reactor pressure vessel materials, on the improvement of surveillance temperature measurement, on the validation of the Master Curve approach, and on ND techniques to monitor ageing of irradiated steels. The paper describes the objectives of the new fifth Framework Program projects and how they are part of the AMES strategy, pointing out the involvement of CEEC and NIS countries. (authors)

  11. Mutagenicity of automobile workshop soil leachate and tobacco industry wastewater using the Ames Salmonella fluctuation and the SOS chromotests.

    Science.gov (United States)

    Okunola, Alabi A; Babatunde, Esan E; Chinwe, Duru; Pelumi, Oyedele; Ramatu, Salihu G

    2016-06-01

    Environmental management of industrial solid wastes and wastewater is an important economic and environmental health problem globally. This study evaluated the mutagenic potential of automobile workshop soil-simulated leachate and tobacco wastewater using the SOS chromotest on Escherichia coli PQ37 and the Ames Salmonella fluctuation test on Salmonella typhimurium strains TA98 and TA100 without metabolic activation. Physicochemical parameters of the samples were also analyzed. The result of the Ames test showed mutagenicity of the test samples. However, the TA100 was the more responsive strain for both the simulated leachate and tobacco wastewater in terms of mutagenic index in the absence of metabolic activation. The SOS chromotest results were in agreement with those of the Ames Salmonella fluctuation test. Nevertheless, the E. coli PQ37 system was slightly more sensitive than the Salmonella assay for detecting genotoxins in the tested samples. Iron, cadmium, manganese, copper, nickel, chromium, arsenic, zinc, and lead contents analyzed in the samples were believed to play significant role in the observed mutagenicity in the microbial assays. The results of this study showed that the simulated leachate and tobacco wastewater showed strong indication of a genotoxic risk. Further studies would be required in the analytical field in order to identify and quantify other compounds not analyzed for in this study, some of which could be responsible for the observed genotoxicity. This will be necessary in order to identify the sources of toxicants and thus to take preventive and/or curative measures to limit the toxicity of these types of wastes. PMID:25187319

  12. The Ames Virtual Environment Workstation: Implementation issues and requirements

    Science.gov (United States)

    Fisher, Scott S.; Jacoby, R.; Bryson, S.; Stone, P.; Mcdowall, I.; Bolas, M.; Dasaro, D.; Wenzel, Elizabeth M.; Coler, C.; Kerr, D.

    1991-01-01

    This presentation describes recent developments in the implementation of a virtual environment workstation in the Aerospace Human Factors Research Division of NASA's Ames Research Center. Introductory discussions are presented on the primary research objectives and applications of the system and on the system's current hardware and software configuration. Principle attention is then focused on unique issues and problems encountered in the workstation's development with emphasis on its ability to meet original design specifications for computational graphics performance and for associated human factors requirements necessary to provide compelling sense of presence and efficient interaction in the virtual environment.

  13. Voluntary cleanup of the Ames chemical disposal site

    International Nuclear Information System (INIS)

    The U.S. Department of Energy completed a voluntary removal action at the Ames chemical disposal site, a site associated with the early days of the Manhattan Project. It contained chemical and low-level radioactive wastes from development of the technology to extract uranium from uranium oxide. The process included the preparation of a Remedial Investigation, Feasibility Study, Baseline Risk Assessment, and, ultimately, issuance of a Record of Decision. Various stakeholder groups were involved, including members of the regulatory community, the general public, and the landowner, Iowa State University. The site was restored and returned to the landowner for unrestricted use.

  14. The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice.

    Science.gov (United States)

    Puig, Kendra L; Kulas, Joshua A; Franklin, Whitney; Rakoczy, Sharlene G; Taglialatela, Giulio; Brown-Borg, Holly M; Combs, Colin K

    2016-04-01

    APP/PS1 double transgenic mice expressing human mutant amyloid precursor protein (APP) and presenilin-1 (PS1) demonstrate robust brain amyloid beta (Aβ) peptide containing plaque deposition, increased markers of oxidative stress, behavioral dysfunction, and proinflammatory gliosis. On the other hand, lack of growth hormone, prolactin, and thyroid-stimulating hormone due to a recessive mutation in the Prop 1 gene (Prop1df) in Ames dwarf mice results in a phenotype characterized by potentiated antioxidant mechanisms, improved learning and memory, and significantly increased longevity in homozygous mice. Based on this, we hypothesized that a similar hormone deficiency might attenuate disease changes in the brains of APP/PS1 mice. To test this idea, APP/PS1 mice were crossed to the Ames dwarf mouse line. APP/PS1, wild-type, df/+, df/df, df/+/APP/PS1, and df/df/APP/PS1 mice were compared at 6 months of age through behavioral testing and assessing amyloid burden, reactive gliosis, and brain cytokine levels. df/df mice demonstrated lower brain growth hormone and insulin-like growth factor 1 concentrations. This correlated with decreased astrogliosis and microgliosis in the df/df/APP/PS1 mice and, surprisingly, reduced Aβ plaque deposition and Aβ 1-40 and Aβ 1-42 concentrations. The df/df/APP/PS1 mice also demonstrated significantly elevated brain levels of multiple cytokines in spite of the attenuated gliosis. These data indicate that the df/df/APP/PS1 line is a unique resource in which to study aging and resistance to disease and suggest that the affected pituitary hormones may have a role in regulating disease progression. PMID:26973101

  15. Processing Earth Observing images with Ames Stereo Pipeline

    Science.gov (United States)

    Beyer, R. A.; Moratto, Z. M.; Alexandrov, O.; Fong, T.; Shean, D. E.; Smith, B. E.

    2013-12-01

    ICESat with its GLAS instrument provided valuable elevation measurements of glaciers. The loss of this spacecraft caused a demand for alternative elevation sources. In response to that, we have improved our Ames Stereo Pipeline (ASP) software (version 2.1+) to ingest satellite imagery from Earth satellite sources in addition to its support of planetary missions. This enables the open source community a free method to generate digital elevation models (DEM) from Digital Globe stereo imagery and alternatively other cameras using RPC camera models. Here we present details of the software. ASP is a collection of utilities written in C++ and Python that implement stereogrammetry. It contains utilities to manipulate DEMs, project imagery, create KML image quad-trees, and perform simplistic 3D rendering. However its primary application is the creation of DEMs. This is achieved by matching every pixel between the images of a stereo observation via a hierarchical coarse-to-fine template matching method. Matched pixels between images represent a single feature that is triangulated using each image's camera model. The collection of triangulated features represents a point cloud that is then grid resampled to create a DEM. In order for ASP to match pixels/features between images, it requires a search range defined in pixel units. Total processing time is proportional to the area of the first image being matched multiplied by the area of the search range. An incorrect search range for ASP causes repeated false positive matches at each level of the image pyramid and causes excessive processing times with no valid DEM output. Therefore our system contains automatic methods for deducing what the correct search range should be. In addition, we provide options for reducing the overall search range by applying affine epipolar rectification, homography transform, or by map projecting against a prior existing low resolution DEM. Depending on the size of the images, parallax, and image

  16. Selected Topics in Overset Technology Development and Applications At NASA Ames Research Center

    Science.gov (United States)

    Chan, William M.; Kwak, Dochan (Technical Monitor)

    2002-01-01

    This paper presents a general overview of overset technology development and applications at NASA Ames Research Center. The topics include: 1) Overview of overset activities at NASA Ames; 2) Recent developments in Chimera Grid Tools; 3) A general framework for multiple component dynamics; 4) A general script module for automating liquid rocket sub-systems simulations; and 5) Critical future work.

  17. Joseph Ames's "Typographical Antiquities" and the Antiquarian Tradition

    Science.gov (United States)

    Shiner, Elaine

    2013-01-01

    One of the most famous historical documents of English printing is Joseph Ames's "Typographical Antiquities," published in London in 1749. Although Ames referred to his work as a history of printing, the bulk of it is a list of the first printers in England and their works through 1600, with very full bibliographical descriptions…

  18. The AMES network in the 6th Framework Programme

    International Nuclear Information System (INIS)

    The AMES (Ageing Materials European Strategy) European network started its activity in 1993 with the aim of studying ageing mechanisms and remedial procedures for structural materials used for nuclear reactor components. Operated by JRC-IE, it has been supporting the co-ordination of the project cluster throughout the 4th and 5th EURATOM Framework Programs, carrying out projects on with plant life management implications. Among them we can list the development of non-destructive techniques applied to thermal ageing and neutron embrittlement monitoring (AMES-NDT and GRETE), improved surveillance for VVER 440 reactors (COBRA), dosimetry (AMESDOSIMETRY, MADAM and REDOS), chemical composition effects on neutron embrittlement (PISA) and advanced fracture mechanics for integrity assessment (FRAME). Main frame of the network in the 5th Framework Programme is the ATHENA project, which is aimed at summarizing the obtained achievements and edit guidelines on important issues like the Master Curve, Effect of chemical composition on embrittlement rate in RPV steels, Re-embrittlement models validation after VVER-440 annealing and open issues in embrittlement of VVER type reactors. In the 6th EURATOM Framework Programme started in 2003 the network will be part of a broader initiative on PLIM including in a more integrated way NESC, ENIQ, NET and AMALIA networks. This paper shows an overview of the concluded projects, achievements of the running ones and open issues tackled in the 6th EURATOM FWP and a summary of the plans for a new broader network on NPP Plant Life management (SAFELIFE). (author)

  19. A Perspective on NASA Ames Air Traffic Management Research

    Science.gov (United States)

    Schroeder, Jeffery A.

    2012-01-01

    This paper describes past and present air-traffic-management research at NASA Ames Research Center. The descriptions emerge from the perspective of a technical manager who supervised the majority of this research for the last four years. Past research contributions built a foundation for calculating accurate flight trajectories to enable efficient airspace management in time. That foundation led to two predominant research activities that continue to this day - one in automatically separating aircraft and the other in optimizing traffic flows. Today s national airspace uses many of the applications resulting from research at Ames. These applications include the nationwide deployment of the Traffic Management Advisor, new procedures enabling continuous descent arrivals, cooperation with industry to permit more direct flights to downstream way-points, a surface management system in use by two cargo carriers, and software to evaluate how well flights conform to national traffic management initiatives. The paper concludes with suggestions for prioritized research in the upcoming years. These priorities include: enabling more first-look operational evaluations, improving conflict detection and resolution for climbing or descending aircraft, and focusing additional attention on the underpinning safety critical items such as a reliable datalink.

  20. NASA Ames Sustainability Initiatives: Aeronautics, Space Exploration, and Sustainable Futures

    Science.gov (United States)

    Grymes, Rosalind A.

    2015-01-01

    In support of the mission-specific challenges of aeronautics and space exploration, NASA Ames produces a wealth of research and technology advancements with significant relevance to larger issues of planetary sustainability. NASA research on NexGen airspace solutions and its development of autonomous and intelligent technologies will revolutionize both the nation's air transporation systems and have applicability to the low altitude flight economy and to both air and ground transporation, more generally. NASA's understanding of the Earth as a complex of integrated systems contributes to humanity's perception of the sustainability of our home planet. Research at NASA Ames on closed environment life support systems produces directly applicable lessons on energy, water, and resource management in ground-based infrastructure. Moreover, every NASA campus is a 'city'; including an urbanscape and a workplace including scientists, human relations specialists, plumbers, engineers, facility managers, construction trades, transportation managers, software developers, leaders, financial planners, technologists, electricians, students, accountants, and even lawyers. NASA is applying the lessons of our mission-related activities to our urbanscapes and infrastructure, and also anticipates a leadership role in developing future environments for living and working in space.

  1. Freeze-out configuration properties in the 197Au + 197Au reaction at 23 AMeV

    CERN Document Server

    Najman, R; Sochocka, A; Amorini, F; Auditore, L; Cap, T; Cardella, G; De Filippo, E; Geraci, E; Grzeszczuk, A; Kowalski, S; Kozik, T; Lanzalone, G; Lombardo, I; Majka, Z; Nicolis, N G; Pagano, A; Piasecki, E; Pirrone, S; Politi, G; Rizzo, F; Russotto, P; Siwek-Wilczynska, K; Skwira-Chalot, I; Trifiro, A; Trimarchi, M; Wilczynski, J; Zipper, W

    2015-01-01

    Data from the experiment on the 197Au + 197Au reaction at 23 AMeV are analyzed with an aim to find signatures of exotic nuclear configurations such as toroid-shaped objects. The experimental data are compared with predictions of the ETNA code dedicated to look for such configurations and with the QMD model. A novel criterion of selecting events possibly resulting from the formation of exotic freeze-out configurations, "the efficiency factor", is tested. Comparison between experimental data and model predictions may indicate for the formation of flat/toroidal nuclear systems.

  2. Applied Computational Fluid Dynamics at NASA Ames Research Center

    Science.gov (United States)

    Holst, Terry L.; Kwak, Dochan (Technical Monitor)

    1994-01-01

    The field of Computational Fluid Dynamics (CFD) has advanced to the point where it can now be used for many applications in fluid mechanics research and aerospace vehicle design. A few applications being explored at NASA Ames Research Center will be presented and discussed. The examples presented will range in speed from hypersonic to low speed incompressible flow applications. Most of the results will be from numerical solutions of the Navier-Stokes or Euler equations in three space dimensions for general geometry applications. Computational results will be used to highlight the presentation as appropriate. Advances in computational facilities including those associated with NASA's CAS (Computational Aerosciences) Project of the Federal HPCC (High Performance Computing and Communications) Program will be discussed. Finally, opportunities for future research will be presented and discussed. All material will be taken from non-sensitive, previously-published and widely-disseminated work.

  3. Ames Laboratory site environmental report, Calendar year 1994

    International Nuclear Information System (INIS)

    The Ames Laboratory conducts fundamental research in the physical, chemical, materials, and mathematical sciences and engineering which underlie energy generating, conversion, transmission and storage technologies, environmental improvement, and other technical areas essential to national needs. These efforts will be maintained so as to contribute to the achievement of the vision of DOE and, more specifically, to increase the general levels of knowledge and technical capabilities, to prepare engineering and physical sciences students for the future, both academia and industry, and to develop new technologies and practical applications from our basic scientific programs that will contribute to a strengthening of the US economy. The Laboratory approaches all its operations with the safety and health of all workers as a constant objective and with genuine concern for the environment. The Laboratory relies upon its strengths in materials synthesis and processing, materials reliability, chemical analysis, chemical sciences, photosynthesis, materials sciences, metallurgy, high-temperature superconductivity, and applied mathematical sciences to conduct the long term basic and intermediate range applied research needed to solve the complex problems encountered in energy production, and utilization as well as environmental restoration and waste management. Ames Laboratory will continue to maintain a very significant and highly beneficial pre-college math and science education program which currently serves both teachers and students at the middle school and high school levels. Our technology transfer program is aided by joint efforts with ISU's technology development and commercialization enterprise and will sustain concerted efforts to implement Cooperative Research and Development Agreements, industrially sponsored Work for Others projects. and scientific personnel exchanges with our various customers

  4. Overview of two-dimensional airfoil research at Ames Research Center

    Science.gov (United States)

    Chapman, G. T.

    1979-01-01

    The five basic elements of the two dimensional airfoil research program at Ames Research Center are illustrated. These elements are experimental, theoretical (including computational), validation, design optimization, and industry interaction. Each area is briefly discussed.

  5. Making Stuff Outreach at the Ames Laboratory and Iowa State University

    Energy Technology Data Exchange (ETDEWEB)

    Ament, Katherine; Karsjen, Steven; Leshem-Ackerman, Adah; King, Alexander

    2011-04-01

    The U. S. Department of Energy's Ames Laboratory in Ames, Iowa was a coalition partner for outreach activities connected with NOVA's Making Stuff television series on PBS. Volunteers affiliated with the Ames Laboratory and Iowa State University, with backgrounds in materials science, took part in activities including a science-themed Family Night at a local mall, Science Cafes at the Science Center of Iowa, teacher workshops, demonstrations at science nights in elementary and middle schools, and various other events. We describe a selection of the activities and present a summary of their outcomes and extent of their impact on Ames, Des Moines and the surrounding communities in Iowa. In Part 2, results of a volunteer attitude survey are presented, which shed some light on the volunteer experience and show how the volunteers participation in outreach activities has affected their views of materials education.

  6. Analysis of Hexanitrostilbene (HNS) and Dipicryethane (DPE) for Mutagenicity by the Ames/Salmonella Assay

    Energy Technology Data Exchange (ETDEWEB)

    Wu, R; Felton, J

    2007-10-12

    The Ames/Salmonella assay, developed by Professor Bruce Ames at the University of California, Berkeley, is a rapid and sensitive assay for detecting mutagenicity of various chemical compounds (Maron and Ames, 1983). It is a widely accepted short-term assay for detecting chemicals that induce mutations in the histidine (his) gene of Salmonella typhimurium. This is a reverse mutation assay that detects the mutational reversion of his-dependent Salmonella to the his-independent counterpart. Thereby, mutagenic compounds will increase the frequency of occurrence of his-independent bacterial colonies. The assay utilizes the specific genetically constructed strains of bacteria either with or without mammalian metabolic activation enzymes (S9), Aroclor induced rat liver homogenate to assess the mutagenicity of different compounds. In this study, we will use the Ames/Salmonella assay to investigate the mutagenicity of Hexanitrostilbene (HNS) from both Bofors and Pantex, and Dipicryethane (DPE).

  7. Thyroxine modifies the effects of growth hormone in Ames dwarf mice

    OpenAIRE

    Do, Andrew; Menon, Vinal; Zhi, Xu; Gesing, Adam; Wiesenborn, Denise S.; Spong, Adam; Sun, Liou; Bartke, Andrzej; Masternak, Michal M.

    2015-01-01

    Ames dwarf (df/df) mice lack growth hormone (GH), thyroid stimulating hormone and prolactin. Treatment of juvenile df/df mice with GH alone stimulates somatic growth, reduces insulin sensitivity and shortens lifespan. Early‐life treatment with thyroxine (T4) alone produces modest growth stimulation but does not affect longevity. In this study, we examined the effects of treatment of juvenile Ames dwarf mice with a combination of GH + T4 and compared them to the effects of GH alone. Treatment ...

  8. Methionine flux to transsulfuration is enhanced in the long living Ames dwarf mouse

    OpenAIRE

    Uthus, Eric O; Holly M. Brown-Borg

    2006-01-01

    Long-lived Ames dwarf mice lack growth hormone, prolactin, and thyroid stimulating hormone. Additionally the dwarf mice have enzyme activities and levels that combat oxidative stress more efficiently than those of normal mice. We have shown that methionine metabolism in Ames mice is markedly different than in their wild type littermates. In our previous work we hypothesized that the flux of methionine to the transsulfuration pathway is enhanced in the dwarf mice. The current study was designe...

  9. Mobile technologies in medical education: AMEE Guide No. 105.

    Science.gov (United States)

    Masters, Ken; Ellaway, Rachel H; Topps, David; Archibald, Douglas; Hogue, Rebecca J

    2016-06-01

    Mobile technologies (including handheld and wearable devices) have the potential to enhance learning activities from basic medical undergraduate education through residency and beyond. In order to use these technologies successfully, medical educators need to be aware of the underpinning socio-theoretical concepts that influence their usage, the pre-clinical and clinical educational environment in which the educational activities occur, and the practical possibilities and limitations of their usage. This Guide builds upon the previous AMEE Guide to e-Learning in medical education by providing medical teachers with conceptual frameworks and practical examples of using mobile technologies in medical education. The goal is to help medical teachers to use these concepts and technologies at all levels of medical education to improve the education of medical and healthcare personnel, and ultimately contribute to improved patient healthcare. This Guide begins by reviewing some of the technological changes that have occurred in recent years, and then examines the theoretical basis (both social and educational) for understanding mobile technology usage. From there, the Guide progresses through a hierarchy of institutional, teacher and learner needs, identifying issues, problems and solutions for the effective use of mobile technology in medical education. This Guide ends with a brief look to the future. PMID:27010681

  10. Estimation of the dermal carcinogenic activity of petroleum fractions using a modified Ames assay.

    Science.gov (United States)

    Blackburn, G R; Deitch, R A; Schreiner, C A; Mehlman, M A; Mackerer, C R

    1984-10-01

    The Ames Salmonella/microsomal activation mutagenesis assay has been adapted to improve sensitivity to complex hydrocarbon mixtures produced by the refining of petroleum. Extraction of oil samples with dimethyl sulfoxide produces aqueous-compatible solutions that more easily interact with the tester bacteria. These extracts, therefore, produce higher revertant values than do equivalent volumes of oil delivered neat or dissolved in organic solvent. Parallel increases in the liver microsomal S-9 concentration further improve the sensitivity of the assay, allowing detection of mutagenicity in otherwise inactive samples. The effect of increased microsomal fraction from rodent liver is apparently attributable to the higher levels of activating enzymes rather than to the concomitant increase in the overall hydrophobicity of the test system. The modified assay has been used to rank thirteen petroleum-derived oils and a corn oil control for relative mutagenic activity. This ranking closely correlates (r = 0.97) with potency rankings of the same samples previously determined from dermal carcinogenicity bioassays. PMID:6401126

  11. Corrective Action Plan in response to the March 1992 Tiger Team Assessment of the Ames Laboratory

    International Nuclear Information System (INIS)

    On March 5, 1992, a Department of Energy (DOE) Tiger Team completed an assessment of the Ames Laboratory, located in Ames, Iowa. The purpose of the assessment was to provide the Secretary of Energy with a report on the status and performance of Environment, Safety and Health (ES ampersand H) programs at Ames Laboratory. Detailed findings of the assessment are presented in the report, DOE/EH-0237, Tiger Team Assessment of the Ames Laboratory. This document, the Ames Laboratory Corrective Action Plan (ALCAP), presents corrective actions to overcome deficiencies cited in the Tiger Team Assessment. The Tiger Team identified 53 Environmental findings, from which the Team derived four key findings. In the Safety and Health (S ampersand H) area, 126 concerns were identified, eight of which were designated Category 11 (there were no Category I concerns). Seven key concerns were derived from the 126 concerns. The Management Subteam developed 19 findings which have been summarized in four key findings. The eight S ampersand H Category 11 concerns identified in the Tiger Team Assessment were given prompt management attention. Actions to address these deficiencies have been described in individual corrective action plans, which were submitted to DOE Headquarters on March 20, 1992. The ALCAP includes actions described in this early response, as well as a long term strategy and framework for correcting all remaining deficiencies. Accordingly, the ALCAP presents the organizational structure, management systems, and specific responses that are being developed to implement corrective actions and to resolve root causes identified in the Tiger Team Assessment. The Chicago Field Office (CH), IowaState University (ISU), the Institute for Physical Research and Technology (IPRT), and Ames Laboratory prepared the ALCAP with input from the DOE Headquarters, Office of Energy Research (ER)

  12. Comparison of acoustic data from a 102 mm conic nozzle as measured in the RAE 24-foot wind tunnel and the NASA Ames 40- by 80-foot wind tunnel

    Science.gov (United States)

    Atencio, A., Jr.; Mckie, J.

    1982-01-01

    A cooperative program between the Royal Aircraft Establishment (RAE), England, and the NASA Ames Research Center was initiated to compare acoustic measurements made in the RAE 24-foot wind tunnel and in the Ames 40- by 80-foot wind tunnel. The acoustic measurements were made in both facilities using the same 102 mm conical nozzle supplied by the RAE. The nozzle was tested by each organization using its respective jet test rig. The mounting hardware and nozzle exit conditions were matched as closely as possible. The data from each wind tunnel were independently analyzed by the respective organization. The results from these tests show good agreement. In both facilities, interference with acoustic measurement is evident at angles in the forward quadrant.

  13. Recent Geological and Hydrological Activity in Amazonis and Elysium Basins and Their Link, Marte Valles (AME): Prime Target for Future Reconnaissance

    Science.gov (United States)

    Dohm, J. M.; Robbins, S. J.; Hynek, B. M.

    2012-03-01

    Amazonis and Elysium basins and their link, Marte Vallis (AME), uniquely point to a geologically and hydrologically active Mars. We will present evidence for why AME reconnaissance can help address whether Mars is geologically, hydrologically, and biologically active.

  14. A Survey of Knowledge Management Research & Development at NASA Ames Research Center

    Science.gov (United States)

    Keller, Richard M.; Clancy, Daniel (Technical Monitor)

    2002-01-01

    This chapter catalogs knowledge management research and development activities at NASA Ames Research Center as of April 2002. A general categorization scheme for knowledge management systems is first introduced. This categorization scheme divides knowledge management capabilities into five broad categories: knowledge capture, knowledge preservation, knowledge augmentation, knowledge dissemination, and knowledge infrastructure. Each of nearly 30 knowledge management systems developed at Ames is then classified according to this system. Finally, a capsule description of each system is presented along with information on deployment status, funding sources, contact information, and both published and internet-based references.

  15. The NASA Ames Polycyclic Aromatic Hydrocarbon Infrared Spectroscopic Database : The Computed Spectra

    NARCIS (Netherlands)

    Bauschlicher, C. W.; Boersma, C.; Ricca, A.; Mattioda, A. L.; Cami, J.; Peeters, E.; de Armas, F. Sanchez; Saborido, G. Puerta; Hudgins, D. M.; Allamandola, L. J.

    2010-01-01

    The astronomical emission features, formerly known as the unidentified infrared bands, are now commonly ascribed to polycyclic aromatic hydrocarbons (PAHs). The laboratory experiments and computational modeling done at the NASA Ames Research Center to create a collection of PAH IR spectra relevant t

  16. Ames collaborative study of cosmic-ray neutrons. II. Low- and mid-latitude flights

    International Nuclear Information System (INIS)

    The continuing progress of the Ames Collaborative Study of Cosmic Ray Neutrons is described. Data obtained aboard flights from Hawaii at altitudes of 41,000 and 45,000 feet, and in the range of geomagnetic latitude 170N less than or equal to lambda less than or equal to 210N are reported. Preliminary estimates of neutron spectra were made

  17. AME - Asteroseismology Made Easy. Estimating stellar properties by use of scaled models

    CERN Document Server

    Lundkvist, M; Aguirre, V Silva

    2014-01-01

    We present a new method to obtain stellar properties for stars exhibiting solar-like oscillations in an easy, fast, and transparent way. The method, called Asteroseismology Made Easy (AME), can determine stellar masses, mean-densities, radii, and surface gravities, as well as estimate ages. In this writing we present AME as a visual and powerful tool which could be useful; in particular in the light of the large number of exoplanets being found. AME consists of a set of figures from which the stellar parameters are deduced. These figures are made from a grid of stellar evolutionary models that cover masses ranging from 0.7 Msun to 1.6 Msun in steps of 0.1 Msun and metallicities in the interval -0.3 dex <= [Fe/H] <= +0.3 dex in increments of 0.1 dex. The stellar evolutionary models are computed using the Modules for Experiments in Stellar Astrophysics (MESA) code with simple input physics. We have compared the results from AME with results for three groups of stars; stars with radii determined from inter...

  18. LYRA and other projects on RPV steel embrittlement study and mitigation of the AMES network

    International Nuclear Information System (INIS)

    Within the framework of the European Network AMES, Ageing Materials evaluation and Studies, a number of experimental works on RPV materials embrittlement are carried out at the Institute of Advanced Materials (AIM) of the Joint Research Centre (JRC) of the European Commission (EC). The objectives of AMES are mainly the understanding of the property degradation phenomena of RPV western reference steels like JRQ and HSST, eastern RPV steels like 15X2mFA and 15H2X15, and annealing possibilities. In order to conduct a very high quality irradiation rig, LYRA facility, has been designed and developed at the High Flux Reactor (HFR) Petten. An other dedicated rig, named LIMA, has been developed at the HFR Petten in order to irradiate RPV steels, internals and in-core materials under typical BWR/PWR conditions. The samples can be irradiated in pressurised water up to 160 bar, 320 deg. C, and the water chemistry fully controlled. For irradiation of standard or miniaturised LWR related materials samples, another group of well experienced irradiation devices with inert gas or liquid metals environment are employed. These devices are tailored to their various specific applications. This paper is intended to give information about the structure and the objectives of the existing European network AMES, and to present the various AMES main and spin-off projects, including a brief description on he modelling activities related to RPV materials embrittlement. (author)

  19. Performance of the OVERFLOW-MLP and LAURA-MLP CFD Codes on the NASA Ames 512 CPU Origin System

    Science.gov (United States)

    Taft, James R.

    2000-01-01

    The shared memory Multi-Level Parallelism (MLP) technique, developed last year at NASA Ames has been very successful in dramatically improving the performance of important NASA CFD codes. This new and very simple parallel programming technique was first inserted into the OVERFLOW production CFD code in FY 1998. The OVERFLOW-MLP code's parallel performance scaled linearly to 256 CPUs on the NASA Ames 256 CPU Origin 2000 system (steger). Overall performance exceeded 20.1 GFLOP/s, or about 4.5x the performance of a dedicated 16 CPU C90 system. All of this was achieved without any major modification to the original vector based code. The OVERFLOW-MLP code is now in production on the inhouse Origin systems as well as being used offsite at commercial aerospace companies. Partially as a result of this work, NASA Ames has purchased a new 512 CPU Origin 2000 system to further test the limits of parallel performance for NASA codes of interest. This paper presents the performance obtained from the latest optimization efforts on this machine for the LAURA-MLP and OVERFLOW-MLP codes. The Langley Aerothermodynamics Upwind Relaxation Algorithm (LAURA) code is a key simulation tool in the development of the next generation shuttle, interplanetary reentry vehicles, and nearly all "X" plane development. This code sustains about 4-5 GFLOP/s on a dedicated 16 CPU C90. At this rate, expected workloads would require over 100 C90 CPU years of computing over the next few calendar years. It is not feasible to expect that this would be affordable or available to the user community. Dramatic performance gains on cheaper systems are needed. This code is expected to be perhaps the largest consumer of NASA Ames compute cycles per run in the coming year.The OVERFLOW CFD code is extensively used in the government and commercial aerospace communities to evaluate new aircraft designs. It is one of the largest consumers of NASA supercomputing cycles and large simulations of highly resolved full

  20. Diagnóstico molecular diferencial Colletotrichum gloeosporioides y Fusarium oxysporum en ñame (Dioscorea sp.

    Directory of Open Access Journals (Sweden)

    Yeimy Alexandra Pinzón Gutiérrez

    2013-06-01

    ón conidial, a su acentuada incidencia en suelo que es su hábitat natural y a su prolongada sobrevivencia.Palabras clave: ñame; Colletotrichum gloeosporioides;  Fusarium oxysporum; factor de elongación alpha (EF-α; antracnosis; pudrición.Abstract: Fungal diseases are responsible for the greatest losses of yam crops in  Colombia; among  which,the anthracnose stands out as the most devastating. Recently,  low prevalence fungi with high spread power such as F. oxysporum have increased their presence in yam crops causing diseases like tubers decomposition post-harvest. Despite the importance of yam crop on the Colombian Caribbean Coast, the Pacific and the Amazon; this is considered an orphan crop due to  the little effort and  investigation in the world and particularly in Colombia.  In order to contribute to the proper and timely diagnose of fitopathogens that affects  yam crop, in this study fungal isolates from leaves with necrotic spots were obtained, of which five showed morphological characteristics of the Colletotrichum genus and three of the Fusarium genus. The identity of species involved was determined by ITS of ADNr secuencing, corresponding to Colletotrichum gloeosporioides and Fusarium oxysporum. The evaluation of molecular markers for differential and simultaneous detection of these pathogens, allowed to choose the elongation factor alpha (EF-α as the best diagnostic test.  Pathogenicity test confirmed the capacity of C. gloeosporioides to cause anthracnose symptomatology in leaves and F. oxysporum isolates to trigger rot in tuber, whose presence in leaves could be associated with its easy and fast conidial spread, to its high presence in soil which is its natural habitat, and its extended survival.Key words: yam; Colletotrichum gloeosporioides; Fusarium oxysporum; elongation factor alpha (EF-α;  anthracnose; rot

  1. An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential

    Directory of Open Access Journals (Sweden)

    McCarren Patrick

    2011-11-01

    Full Text Available Abstract Background In drug discovery, a positive Ames test for bacterial mutation presents a significant hurdle to advancing a drug to clinical trials. In a previous paper, we discussed success in predicting the genotoxicity of reagent-sized aryl-amines (ArNH2, a structure frequently found in marketed drugs and in drug discovery, using quantum mechanics calculations of the energy required to generate the DNA-reactive nitrenium intermediate (ArNH:+. In this paper we approach the question of what molecular descriptors could improve these predictions and whether external data sets are appropriate for further training. Results In trying to extend and improve this model beyond this quantum mechanical reaction energy, we faced considerable difficulty, which was surprising considering the long history and success of QSAR model development for this test. Other quantum mechanics descriptors were compared to this reaction energy including AM1 semi-empirical orbital energies, nitrenium formation with alternative leaving groups, nitrenium charge, and aryl-amine anion formation energy. Nitrenium formation energy, regardless of the starting species, was found to be the most useful single descriptor. External sets used in other QSAR investigations did not present the same difficulty using the same methods and descriptors. When considering all substructures rather than just aryl-amines, we also noted a significantly lower performance for the Novartis set. The performance gap between Novartis and external sets persists across different descriptors and learning methods. The profiles of the Novartis and external data are significantly different both in aryl-amines and considering all substructures. The Novartis and external data sets are easily separated in an unsupervised clustering using chemical fingerprints. The chemical differences are discussed and visualized using Kohonen Self-Organizing Maps trained on chemical fingerprints, mutagenic substructure

  2. Emission Spectroscopic Measurements with an Optical Probe in the NASA Ames IHF Arc Jet Facility

    Science.gov (United States)

    Winter, Michael; Prabhu, Dinesh K.; Raiche, George A.; Terrazas-Salinas, Imelda; Hui, Frank C. L.

    2011-01-01

    An optical probe was designed to measure radiation (from inside the arc heater) incident on a test sample immersed in the arc-heated stream. Currently, only crude estimates are available for this incident radiation. Unlike efforts of the past, where the probe line of sight was inclined to the nozzle centerline, the present development focuses on having the probe line of sight coincide with the nozzle centerline. A fiber-coupled spectrometer was used to measure the spectral distribution of incident radiation in the wavelength range of 225 to 900 nm. The radiation heat flux in this wavelength range was determined by integration of measured emission spectral intensity calibrated to incident irradiance from an integrating sphere. Two arc-heater conditions, corresponding to stream bulk enthalpy levels of 12 and 22 MJ/kg, were investigated in the 13-inch diameter nozzle of the Interaction Heating Facility at NASA Ames Research Center. With the probe placed at a distance of 10 inches from the nozzle exit plane, total radiative heat fluxes were measured to be 3.3 and 8.4 W/sq cm for the 12 and 22 MJ/kg conditions, respectively. About 17% of these radiative fluxes were due to bound-bound radiation from atoms and molecules, while the remaining 83% could be attributed to continua (bound-free and/or free-free). A comparison with spectral simulation based on CFD solutions for the arc-heater flow field and with spectroscopic measurements in the plenum region indicates that more than 95% of the measured radiation is generated in the arc region. The total radiative heat flux from the line radiation could increase by a factor of two through contributions from wavelengths outside the measured range, i.e., from the vacuum ultraviolet (wavelengths less than 225 nm) and the infrared (wavelengths greater than 900 nm). An extrapolation of the continuum radiation to these two wavelength regions was not attempted. In the tested configuration, the measured radiative heat flux accounts for

  3. Test

    DEFF Research Database (Denmark)

    Bendixen, Carsten

    2014-01-01

    Bidrag med en kortfattet, introducerende, perspektiverende og begrebsafklarende fremstilling af begrebet test i det pædagogiske univers.......Bidrag med en kortfattet, introducerende, perspektiverende og begrebsafklarende fremstilling af begrebet test i det pædagogiske univers....

  4. Testing and evaluation of light ablation decontamination

    International Nuclear Information System (INIS)

    This report details the testing and evaluation of light ablation decontamination. It details WINCO contracted research and application of light ablation efforts by Ames Laboratory. Tests were conducted with SIMCON (simulated contamination) coupons and REALCON (actual radioactive metal coupons) under controlled conditions to compare cleaning effectiveness, speed and application to plant process type equipment

  5. M2-F1 mounted in NASA Ames Research Center 40x80 foot wind tunnel

    Science.gov (United States)

    1962-01-01

    After the first attempted ground-tow tests of the M2-F1 in March 1963, the vehicle was taken to the Ames Research Center, Mountain View, CA, for wind-tunnel testing. During these tests, Milt Thompson and others were in the M2-F1 to position the control surfaces for each test. The wingless, lifting body aircraft design was initially conceived as a means of landing an aircraft horizontally after atmospheric reentry. The absence of wings would make the extreme heat of re-entry less damaging to the vehicle. In 1962, Dryden management approved a program to build a lightweight, unpowered lifting body as a prototype to flight test the wingless concept. It would look like a 'flying bathtub,' and was designated the M2-F1, the 'M' referring to 'manned' and 'F' referring to 'flight' version. It featured a plywood shell placed over a tubular steel frame crafted at Dryden. Construction was completed in 1963. The first flight tests of the M2-F1 were over Rogers Dry Lake at the end of a tow rope attached to a hopped-up Pontiac convertible driven at speeds up to about 120 mph. This vehicle needed to be able to tow the M2-F1 on the Rogers Dry Lakebed adjacent to NASA's Flight Research Center (FRC) at a minimum speed of 100 miles per hour. To do that, it had to handle the 400-pound pull of the M2-F1. Walter 'Whitey' Whiteside, who was a retired Air Force maintenance officer working in the FRC's Flight Operations Division, was a dirt-bike rider and hot-rodder. Together with Boyden 'Bud' Bearce in the Procurement and Supply Branch of the FRC, Whitey acquired a Pontiac Catalina convertible with the largest engine available. He took the car to Bill Straup's renowned hot-rod shop near Long Beach for modification. With a special gearbox and racing slicks, the Pontiac could tow the 1,000-pound M2-F1 110 miles per hour in 30 seconds. It proved adequate for the roughly 400 car tows that got the M2-F1 airborne to prove it could fly safely and to train pilots before they were towed behind a C

  6. Results of screening NCI/NTP nongenotoxic carcinogens and genotoxic noncarcinogens with the ke test

    International Nuclear Information System (INIS)

    The interdependence of the electrophilic and carcinogenic properties of chemicals that was demonstrated two decades ago rekindled interest in the somatic mutation theory of carcinogenesis. Interest in this theory grew with the development of a reverse-mutation bacterial assay in the laboratory of B.N. Ames that permitted the mutagenic properties of the chemicals to be determined quickly and yielded results which indicated that ''carcinogens are mutagens.'' Subsequent validation studies of this bioassay, the Salmonella typhimurium/microsome or ''Ames test,'' by Ames' group and others provided additional support for the correlation between mutagenicity and carcinogenicity which led to the worldwide deployment of the Ames test in thousands of laboratories and to the development of more than 100 other short-term tests that continue to be used to identify potential carcinogens via various end-points of genotoxicity. This document discusses electrophilicity, mutagenicity, and carcinogenicity relationships as well as carcinogen-screening of chemicals. 28 refs., 4 tabs

  7. NASA Ames DEVELOP Interns: Helping the Western United States Manage Natural Resources One Project at a Time

    Science.gov (United States)

    Justice, Erin; Newcomer, Michelle

    2010-01-01

    The western half of the United States is made up of a number of diverse ecosystems ranging from arid desert to coastal wetlands and rugged forests. Every summer for the past 7 years students ranging from high school to graduate level gather at NASA Ames Research Center (ARC) as part of the DEVELOP Internship Program. Under the guidance of Jay Skiles [Ames Research Center (ARC) - Ames DEVELOP Manager] and Cindy Schmidt [ARC/San Jose State University Ames DEVELOP Coordinator] they work as a team on projects exploring topics including: invasive species, carbon flux, wetland restoration, air quality monitoring, storm visualizations, and forest fires. The study areas for these projects have been in Washington, Utah, Oregon, Nevada, Hawaii, Alaska and California. Interns combine data from NASA and partner satellites with models and in situ measurements to complete prototype projects demonstrating how NASA data and resources can help communities tackle their Earth Science related problems.

  8. The NASA Ames Hypervelocity Free Flight Aerodynamic Facility: Experimental Simulation of the Atmospheric Break-Up of Meteors

    Science.gov (United States)

    Wilder, M. C.; Bogdanoff, D. W.

    2015-01-01

    The Hypervelocity Free Flight Aerodynamic Facility at NASA Ames Research Center provides a potential platform for the experimental simulation of meteor breakup at conditions that closely match full-scale entry condition for select parameters. The poster describes the entry environment simulation capabilities of the Hypervelocity Free Flight Aerodynamic Facility (HFFAF) at NASA Ames Research Center and provides example images of the fragmentation of a hypersonic projectile for which break-up was initiated by mechanical forces (impact with a thin polymer diaphragm).

  9. Robust Mosaicking of Stereo Digital Elevation Models from the Ames Stereo Pipeline

    Science.gov (United States)

    Kim, Tae Min; Moratto, Zachary M.; Nefian, Ara Victor

    2010-01-01

    Robust estimation method is proposed to combine multiple observations and create consistent, accurate, dense Digital Elevation Models (DEMs) from lunar orbital imagery. The NASA Ames Intelligent Robotics Group (IRG) aims to produce higher-quality terrain reconstructions of the Moon from Apollo Metric Camera (AMC) data than is currently possible. In particular, IRG makes use of a stereo vision process, the Ames Stereo Pipeline (ASP), to automatically generate DEMs from consecutive AMC image pairs. However, the DEMs currently produced by the ASP often contain errors and inconsistencies due to image noise, shadows, etc. The proposed method addresses this problem by making use of multiple observations and by considering their goodness of fit to improve both the accuracy and robustness of the estimate. The stepwise regression method is applied to estimate the relaxed weight of each observation.

  10. Collective effects in Au(100-800 AMeV) + Au semi-central collisions

    International Nuclear Information System (INIS)

    The present work has been carried out in the framework of the experimental program of the FOPI collaboration. It is devoted to a systematic study of the different forms of collective expansion of nuclear matter in semi-central Au+Au collisions at incident energies ranging from 100 AMeV to 800 AMeV. The aim is to investigate the influence of compressional effects, momentum dependence of the nuclear interaction and nucleon-nucleon cross section on the observed phenomena. Important changes in the reaction mechanisms are evidenced, in particular at low incident energies where one observes, on the one hand, a transition from an enhanced in-plane emission to a preferential out-of-plane emission pattern and, on the other hand, a strong reduction of the directed in-plane component. Experimental results are compared to the predictions of the Quantum Molecular Dynamics (QMD) model for different parametrizations of the nuclear interaction. (author)

  11. Evaluation of the NASA-Ames panel method (PMARC) for aerodynamic missile design

    OpenAIRE

    Lambert, Mark A.

    1995-01-01

    The NASA Ames Research Center developed panel code (PMARC) is investigated to explore its suitability for aerodynamic missile design. To this end, PMARC is first assessed by applying it to several problems for which other solutions and experimental data are available, i.e., steady flow past a wing-body configuration, delta wings, biplane wings, wings in ground effect, and unsteady flow of pitching and impulsively started wings. Good agreement is found in all cases. PMARC is then applied to tw...

  12. The contribution of visceral fat to improved insulin signaling in Ames dwarf mice

    OpenAIRE

    Menon, Vinal; Zhi, Xu; Hossain, Tanvir; Bartke, Andrzej; Spong, Adam; Gesing, Adam; Masternak, Michal M.

    2014-01-01

    Ames dwarf (Prop1 df, df/df) mice are characterized by growth hormone (GH), prolactin, and thyrotropin deficiency, remarkable extension of longevity and increased insulin sensitivity with low levels of fasting insulin and glucose. Plasma levels of anti-inflammatory adiponectin are increased in df/df mice, while pro-inflammatory IL-6 is decreased in plasma and epididymal fat. This represents an important shift in the balance between pro- and anti-inflammatory adipokines in adipose tissue, whic...

  13. Study of optical techniques for the Ames unitary wind tunnel: Digital image processing, part 6

    Science.gov (United States)

    Lee, George

    1993-01-01

    A survey of digital image processing techniques and processing systems for aerodynamic images has been conducted. These images covered many types of flows and were generated by many types of flow diagnostics. These include laser vapor screens, infrared cameras, laser holographic interferometry, Schlieren, and luminescent paints. Some general digital image processing systems, imaging networks, optical sensors, and image computing chips were briefly reviewed. Possible digital imaging network systems for the Ames Unitary Wind Tunnel were explored.

  14. Shock Tube and Ballistic Range Facilities at NASA Ames Research Center

    Science.gov (United States)

    Grinstead, Jay H.; Wilder, Michael C.; Reda, Daniel C.; Cornelison, Charles J.; Cruden, Brett A.; Bogdanoff, David W.

    2010-01-01

    The Electric Arc Shock Tube (EAST) facility and the Hypervelocity Free Flight Aerodynamic Facility (HFFAF) at NASA Ames Research Center are described. These facilities have been in operation since the 1960s and have supported many NASA missions and technology development initiatives. The facilities have world-unique capabilities that enable experimental studies of real-gas aerothermal, gas dynamic, and kinetic phenomena of atmospheric entry.

  15. Improving response rates and evaluating nonresponse bias in surveys: AMEE Guide No. 102.

    Science.gov (United States)

    Phillips, Andrew W; Reddy, Shalini; Durning, Steven J

    2016-03-01

    Robust response rates are essential for effective survey-based strategies. Researchers can improve survey validity by addressing both response rates and nonresponse bias. In this AMEE Guide, we explain response rate calculations and discuss methods for improving response rates to surveys as a whole (unit nonresponse) and to questions within a survey (item nonresponse). Finally, we introduce the concept of nonresponse bias and provide simple methods to measure it. PMID:26648511

  16. Mutagenic activity of some coal-derived humic compounds evaluated by the Ames test.

    Science.gov (United States)

    Bernacchi, F; Ponzanelli, I; Barale, R; Loprieno, N

    1996-07-10

    Two coal-derived humic substances (Sulcis and South Africa, Eniricerche, Italy) have been evaluated for their mutagenic activity on TA98 and TA100 Salmonella typhimurium strains, either in presence or in absence of metabolic activation (S9). Both compounds showed no effect on the two strains, as observed with natural humic acid (Fluka). After chlorination, coal-derived humic acids induced a strong dose-related increase in the number of revertants on TA100 without S9, whose extent was directly proportional to the chlorination ratios. Such effect was completely suppressed when a sodium thiosulfate solution (10%) was added at the end of the chlorination period (about 90 h). The analogies with natural humic acid mutagenicity are discussed. PMID:8700175

  17. Mutagenic activity of some coal-derived humic compunds evaluated by the Ames test

    Energy Technology Data Exchange (ETDEWEB)

    Bernacchi, F.; Ponzanelli, I.; Barale, R.; Loprieno, N. [Universita degli Studi di Pisa, Pisa (Italy). Dipt. Scienze dell`Ambiente e del Territorilo

    1996-07-10

    Two coal-derived humic substances were evaluated for their mutagenic activity on TA98 and TA100 Salmonella typhimurium strains, either in the presence or absence of metabolic activation (S9). Both compounds showed no effect on the two strains, as observed with natural humic acid (Fluka). After chlorination, coal-derived humic acids induced a strong dose-related increase in the number of revertants on TA100 without S9, whose extent was directly proportional to the chlorination ratios. Such effect was completely suppressed when a sodium thiosulphate solution (10%) was added at the end of the chlorination period (about 90 h). The analogies with natural humic acid mutagenicity are discussed. 19 refs., 5 tabs.

  18. Estrogenic and mutagenic activities of Crotalaria pallida measured by recombinant yeast assay and Ames test

    OpenAIRE

    Boldrin, Paula Karina; Resende, Flávia Aparecida; Höhne, Ana Paula Oliveira; de Camargo, Mariana Santoro; Espanha, Lívia Greghi; Nogueira, Catarine Haidê; Melo, Maria do Socorro F; Vilegas, Wagner; Varanda, Eliana Aparecida

    2013-01-01

    Background Crotalaria pallida Ailton is a plant belonging to the Fabaceae family, popularly known as “rattle or rattlesnake” and used in traditional medicine to treat swelling of the joints and as a vermifuge. Previous pharmacological studies have also reported anti-inflammatory, antimicrobial and antifungal activities. Nevertheless, scientific information regarding this species is scarce, and there are no reports related to its possible estrogenic and mutagenic effects. Thus, the purpose of ...

  19. An Experimental Study of the Ground Transportation System (GTS) Model in the NASA Ames 7- by 10-Ft Wind Tunnel

    Science.gov (United States)

    Storms, Bruce L.; Ross, James C.; Heineck, James T.; Walker, Stephen M.; Driver, David M.; Zilliac, Gregory G.; Bencze, Daniel P. (Technical Monitor)

    2001-01-01

    The 1/8-scale Ground Transportation System (GTS) model was studied experimentally in the NASA Ames 7- by 10-Ft Wind Tunnel. Designed for validation of computational fluid dynamics (CFD), the GTS model has a simplified geometry with a cab-over-engine design and no tractor-trailer gap. As a further simplification, all measurements of the GTS model were made without wheels. Aerodynamic boattail plates were also tested on the rear of the trailer to provide a simple geometry modification for computation. The experimental measurements include body-axis drag, surface pressures, surface hot-film anemometry, oil-film interferometry, and 3-D particle image velocimetry (PIV). The wind-averaged drag coefficient with and without boattail plates was 0.225 and 0.277, respectively. PIV measurements behind the model reveal a significant reduction in the wake size due to the flow turning provided by the boattail plates. Hot-film measurements on the side of the cab indicate laminar separation with turbulent reattachment within 0.08 trailer width for zero and +/- 10 degrees yaw. Oil film interferometry provided quantitative measurements of skin friction and qualitative oil flow images. A complete set of the experimental data and the surface definition of the model are included on a CD-ROM for further analysis and comparison.

  20. A three-dimensional orthogonal laser velocimeter for the NASA Ames 7- by 10-foot wind tunnel

    Science.gov (United States)

    Dunagan, Stephen E.; Cooper, Donald L.

    1995-01-01

    A three-component dual-beam laser-velocimeter system has been designed, fabricated, and implemented in the 7-by 10-Foot Wind Tunnel at NASA Ames Research Center. The instrument utilizes optical access from both sides and the top of the test section, and is configured for uncoupled orthogonal measurements of the three Cartesian coordinates of velocity. Bragg cell optics are used to provide fringe velocity bias. Modular system design provides great flexibility in the location of sending and receiving optics to adapt to specific experimental requirements. Near-focus Schmidt-Cassegrain optic modules may be positioned for collection of forward or backward scattered light over a large solid angle, and may be clustered to further increase collection solid angle. Multimode fiber optics transmit collected light to the photomultiplier tubes for processing. Counters are used to process the photomultiplier signals and transfer the processed data digitally via buffered interface controller to the host MS-DOS computer. Considerable data reduction and graphical display programming permit on-line control of data acquisition and evaluation of the incoming data. This paper describes this system in detail and presents sample data illustrating the system's capability.

  1. Wall interaction effects for a full-scale helicopter rotor in the NASA Ames 80- by 120-foot wind tunnel

    Science.gov (United States)

    Shinoda, Patrick M.

    1994-01-01

    A full-scale helicopter rotor test was conducted in the NASA Ames 80- by 120-Foot Wind Tunnel with a four-bladed S-76 rotor system. This wind tunnel test generated a unique and extensive data base covering a wide range of rotor shaft angles-of-attack and rotor thrust conditions from 0 to 100 knots. Three configurations were tested: (1) empty tunnel; (2) test stand body (fuselage) and support system; and (3) fuselage and support system with rotor installed. Empty tunnel wall pressure data are evaluated as a function of tunnel speed to understand the baseline characteristics. Aerodynamic interaction effects between the fuselage and the walls of the tunnel are investigated by comparing wall, ceiling, and floor pressures for various tunnel velocities and fuselage angles-of-attack. Aerodynamic interaction effects between the rotor and the walls of the tunnel are also investigated by comparing wall, ceiling, and floor pressures for various rotor shaft angles, rotor thrust conditions, and tunnel velocities. Empty tunnel wall pressure data show good repeatability and are not affected by tunnel speed. In addition, the tunnel wall pressure profiles are not affected by the presence of the fuselage apart from a pressure shift. Results do not indicate that the tunnel wall pressure profiles are affected by the presence of the rotor. Significant changes in the wall, ceiling, and floor pressure profiles occur with changing tunnel speeds for constant rotor thrust and shaft angle conditions. Significant changes were also observed when varying rotor thrust or rotor shaft angle-of-attack. Other results indicate that dynamic rotor loads and blade motion are influenced by the presence of the tunnel walls at very low tunnel velocity and, together with the wall pressure data, provide a good indication of flow breakdown.

  2. Study of optical techniques for the Ames unitary wind tunnels. Part 1: Schlieren

    Science.gov (United States)

    Lee, George

    1992-01-01

    Alignment procedures and conceptual designs for the rapid alignment of the Ames Unitary Wind Tunnel schlieren systems were devised. The schlieren systems can be aligned by translating the light source, the mirrors, and the knife edge equal distances. One design for rapid alignment consists of a manual pin locking scheme. The other is a motorized electronic position scheme. A study of two optical concepts which can be used with the schlieren system was made. These are the 'point diffraction interferometers' and the 'focus schlieren'. Effects of vibrations were studied.

  3. Upper Boundary Extension of the NASA Ames Mars General Circulation Model

    Science.gov (United States)

    Brecht, Amanda S.; Hollingsworth, J. L.; Kahre, M. A.; Schaeffer, J. R.

    2012-01-01

    Extending the NASA Ames Mars General Circulation Model (MGCM) upper boundary will expand our understanding of the connection between the lower and upper atmosphere of Mars through the middle atmosphere. The extension's main requirements is incorporation of Non-local thermodynamic equilibrium (NLTE) heating (visible) and cooling (infrared). NLTE occurs when energy is exchanged more rapidly with the radiation field (or other energy sources) rather than collisions with other molecules. Without NLTE above approximately 80km/approximately 60km in Mars' atmosphere the IR/visible heating rates are overestimated. Currently NLTE has been applied successfully into the 1D RT code and is in progress for the 3D application.

  4. GROWTH HORMONE ABOLISHES BENEFICIAL EFFECTS OF CALORIE RESTRICTION IN LONG-LIVED AMES DWARF MICE

    OpenAIRE

    Gesing, Adam; Al-Regaiey, Khalid A.; Bartke, Andrzej; Masternak, Michal M.

    2014-01-01

    Disruption of the growth hormone (GH) axis promotes longevity and delays aging. In contrast, GH over-expression may lead to accelerated aging and shorter life. Calorie restriction (CR) improves insulin sensitivity and may extend lifespan. Long-lived Ames dwarf (df/df) mice have additional extension of longevity when subjected to 30% CR. The aim of the study was to assess effects of CR or GH replacement therapy separately and as a combined (CR+GH) treatment in GH-deficient df/df and normal mic...

  5. Wind-tunnel investigation of a large-scale VTOL aircraft model with wing root and wing thrust augmentors. [Ames 40 by 80 foot wind tunnel

    Science.gov (United States)

    Aoyagi, K.; Aiken, T. N.

    1979-01-01

    Tests were conducted in the Ames 40 by 80 foot wind tunnel to determine the aerodynamic characteristics of a large-scale V/STOL aircraft model with thrust augmentors. The model had a double-delta wing of aspect ratio 1.65 with augmentors located in the wing root and the wing trailing edge. The supply air for the augmentor primary nozzles was provided by the YJ-97 turbojet engine. The airflow was apportioned approximately 74 percent to the wing root augmentor and 24 percent to wing augmentor. Results were obtained at several trailing-edge flap deflections with the nozzle jet-momentum coefficients ranging from 0 to 7.9. Three-component longitudinal data are presented with the agumentor operating with and without the horizontal tail. A limited amount of six component data are also presented.

  6. An in silico method for predicting Ames activities of primary aromatic amines by calculating the stabilities of nitrenium ions.

    Science.gov (United States)

    Bentzien, Jörg; Hickey, Eugene R; Kemper, Raymond A; Brewer, Mark L; Dyekjaer, Jane D; East, Stephen P; Whittaker, Mark

    2010-02-22

    In this paper, we describe an in silico first principal approach to predict the mutagenic potential of primary aromatic amines. This approach is based on the so-called "nitrenium hypothesis", which was developed by Ford et al. in the early 1990s. This hypothesis asserts that the mutagenic effect for this class of molecules is mediated through the transient formation of a nitrenium ion and that the stability of this cation is correlated with the mutagenic potential. Here we use quantum mechanical calculations at different levels of theory (semiempirical AM1, ab initio HF/3-21G, HF/6-311G(d,p), and DFT/B3LYP/6-311G(d,p)) to compute the stability of nitrenium ions. When applied to a test set of 257 primary aromatic amines, we show that this method can correctly differentiate between Ames active and inactive compounds, and furthermore that it is able to rationalize and predict SAR trends within structurally related chemical series. For this test set, the AM1 nitrenium stability calculations are found to provide a good balance between speed and accuracy, resulting in an overall accuracy of 85%, and sensitivity and specificity of 91% and 72%, respectively. The nitrenium-based predictions are also compared to the commercial software packages DEREK, MULTICASE, and the MOE-Toxicophore descriptor. One advantage of the approach presented here is that the calculation of relative stabilities results in a continuous spectrum of activities and not a simple yes/no answer. This allows us to observe and rationalize subtle trends due to the different electrostatic properties of the organic molecules. Our results strongly indicate that nitrenium ion stability calculations should be used as a complementary approach to assist the medicinal chemist in prioritizing and selecting nonmutagenic primary aromatic amines during preclinical drug discovery programs. PMID:20078034

  7. Investigating the intra-nuclear cascade process using the reaction 136Xe on deuterium at 500 AMeV

    Directory of Open Access Journals (Sweden)

    Rejmund F.

    2010-10-01

    Full Text Available More than 600 residual nuclei, formed in the spallation of 136Xe projectiles impinging on deuterium at 500 AMeV of incident energy, have been unambiguously identified and their production cross sections have been determined with high accuracy. By comparing these data to others previously measured for the reactions 136Xe  +  p at 1 AGeV and 136Xe  +  p at 500 AMeV we investigated the role that neutrons play in peripheral collisions and to understand the energy dissipation in frontal collisions in spallation reactions.

  8. Diagnóstico molecular diferencial colletotrichum gloeosporioides y fusarium oxysporum en ñame (dioscorea sp.)

    OpenAIRE

    Pinzón Gutiérrez, Yeimy Alexandra; Bustamante, Silvia Lizette; Buitrago Hurtado, Gustavo

    2013-01-01

    Título en ingles: Differential molecular diagnosis Colletotrichum gloeosporioides and Fusarium oxysporum in yam (Dioscorea sp.).Título corto:  Diagnóstico molecular en ñameResumen: Las enfermedades de origen fúngico son responsables de las mayores pérdidas reportadas en los cultivos de ñame colombianos, entre ellas la antracnosis causada por Colletotrichum spp. se destaca por ser la más devastadora.  En los últimos años, hongos con baja prevalencia pero con alto poder de diseminación como Fus...

  9. Caracterización molecular del germoplasma de ñame colombiano utilizando "dna amplificaron fingerprinting (daf)" en condiciones radiactivas

    OpenAIRE

    Bustamante, Silvia L.; Guzmán, Mónica; Buitrago, Gustavo

    2007-01-01

    Para la realización de este trabajo se utilizaron muestras de la colección de ñame (Dioscorea spp.) de la Universi­dad de Córdoba y algunas muestras provenientes del IITA (International Institute of Tropical Agriculture, Ibadan, Nigeria), con el fin de caracterizarlas molecularmente y complementar la información que se tiene de ellas. Dada la importancia del cultivo del ñame para los pequeños productores de la costa atlántica, surgió la propuesta de iniciar estudios moleculares en una primera...

  10. The contribution of visceral fat to improved insulin signaling in Ames dwarf mice.

    Science.gov (United States)

    Menon, Vinal; Zhi, Xu; Hossain, Tanvir; Bartke, Andrzej; Spong, Adam; Gesing, Adam; Masternak, Michal M

    2014-06-01

    Ames dwarf (Prop1(df), df/df) mice are characterized by growth hormone (GH), prolactin, and thyrotropin deficiency, remarkable extension of longevity and increased insulin sensitivity with low levels of fasting insulin and glucose. Plasma levels of anti-inflammatory adiponectin are increased in df/df mice, while pro-inflammatory IL-6 is decreased in plasma and epididymal fat. This represents an important shift in the balance between pro- and anti-inflammatory adipokines in adipose tissue, which was not exposed to GH signals during development or adult life. To determine the role of adipose tissue in the control of insulin signaling in these long-living mutants, we examined the effects of surgical removal of visceral (epididymal and perinephric) adipose tissue. Comparison of the results obtained in df/df mice and their normal (N) siblings indicated different effects of visceral fat removal (VFR) on insulin sensitivity and glucose tolerance. The analysis of the expression of genes related to insulin signaling indicated that VFR improved insulin action in skeletal muscle in N mice. Interestingly, this surgical intervention did not improve insulin signaling in df/df mice skeletal muscle but caused suppression of the signal in subcutaneous fat. We conclude that altered profile of adipokines secreted by visceral fat of Ames dwarf mice may act as a key contributor to increased insulin sensitivity and extended longevity of these animals. PMID:24690289

  11. Response of a silicon telescope microdosimeter to 400 AMeV carbon ions

    International Nuclear Information System (INIS)

    A monolithic silicon telescope consisting of a surface ΔE detector 2 μm in thickness coupled to an E detector about 500 μm in thickness made out of a single silicon wafer was recently proposed for the microdosimetric characterization of hadron beams. This device and its pixelated version are intended to be irradiated at the Centro Nazionale di Adroterapia Oncologica (CNAO, National Centre for Oncological Hadrontherapy, Pavia, Italy) with a 400 AMeV carbon ion beam. The response of the silicon microdosimeter under these conditions was calculated with Monte Carlo simulations by using the FLUKA code, in order to have reference available for comparison with the experimental results. - Highlights: • FLUKA simulations performed to study the response of silicon telescope to carbon ions. • Energy distribution of ions from carbon fragmentation were calculated. • Microdosimetric spectra corrected for tissue-equivalence were derived. • Feasibility of the ΔE stage telescope in a 400 AMeV carbon beam was demonstrated

  12. A summary of rotorcraft handling qualities research at NASA Ames Research Center

    Science.gov (United States)

    Chen, R. T.

    1984-01-01

    The objectives of the rotorcraft handling qualities research program at Ames Research Center are twofold: (1) to develop basic handling qualities design criteria to permit cost effective design decisions to be made for helicopters, and (2) to obtain basic handling qualities data for certification of new rotorcraft configurations. The research on the helicopter handling qualities criteria has focused primarily on military nap-of-the-earth (NOE) terrain flying missions, which are flown in day visual meteorological conditions (VMC) and instrument meteorological conditions (IMC), or at night. The Army has recently placed a great deal of emphasis on terrain flying tactics in order to survive and effectively complete the missions in modern and future combat environments. Unfortunately, the existing Military Specification MIL-H 8501A which is a 1961 update of a 1951 document, does not address the handling qualities requirements for terrain flying. The research effort is therefore aimed at filling the void and is being conducted jointly with the Army Aeromechanics Laboratory at Ames. The research on rotorcraft airworthiness standards with respect to flying qualities requirements was conducted to collaboration with the Federal Aviation Administration (FAA).

  13. Assessment of diphenylcyclopropenone for photochemically induced mutagenicity in the Ames assay

    Energy Technology Data Exchange (ETDEWEB)

    Wilkerson, M.G.; Connor, T.H.; Henkin, J.; Wilkin, J.K.; Matney, T.S.

    1987-10-01

    The photochemical conversion of diphenylcyclopropenone to diphenylacetylene has recently been reported. Diphenylcyclopropenone is used in the treatment of alopecia areata and is nonmutagenic in a limited Ames assay. We examined diphenylcyclopropenone and diphenylacetylene, as well as synthetic precursors of diphenylcyclopropenone--dibenzylketone and alpha,alpha'-dibromodibenzylketone--for mutagenicity against TA100, TA98, TA102, UTH8413, and UTH8414. All compounds were nonmutagenic except alpha,alpha'-dibromodibenzylketone, which was a potent mutagen in TA100 with and without S-9 activation. The effect of photochemical activation of diphenylcyclopropenone in the presence of bacteria demonstrated mutagenicity in UTH8413 (two times background) at 10 micrograms/plate with S-9 microsomal activation. 8-Methoxypsoralen produces a mutagenic response in TA102 at 0.1 microgram/plate with 60 seconds of exposure to 350 nm light. In vitro photochemically activated Ames assay with S-9 microsomal fraction may enhance the trapping of short-lived photochemically produced high-energy mutagenic intermediates. This technique offers exciting opportunities to trap high-energy intermediates that may play an important role in mutagenesis. This method can be applied to a variety of topically applied dermatologic agents, potentially subjected to photochemical changes in normal use.

  14. Moessbauer spectroscopic studies of the coordination polymers [A(Me3Sn)3Fe(CN)6]x (A=Me3Sn+, Et4N+, Cp2Fe+, etc.)

    International Nuclear Information System (INIS)

    The structural diagnosis and lattice dynamics of the coordination polymers [(Me3Sn)3Fe(CN)6]x and [A(Me3Sn)3Fe(CN)6]x (A=Me3Sn+, Et4N+, Cp2Fe+, etc.) have been carried out by means of 57Fe- and 119Sn-Moessbauer spectroscopic techniques. The 119Sn-Moessbauer parameters for the polymers indicate that all the tin atoms are coordinated to three methyl groups and two cyano groups, having a trigonal-bipyramidal structure. The temperature dependences of the area under the 119Sn-resonance line for [A(Me3Sn)3Fe(CN)6]x were smaller than that for the host polymer [(Me3Sn)3Fe(CN)6]x. The 57Fe-Moessbauer spectra of [A(Me3Sn)3Fe(CN)6]x show that the iron atoms are Fe(II) in a low-spin state. This suggests that the guest ions are intercalated into the host lattice after reduction of its Fe(III) ions. (orig.)

  15. Proposed Ames M2-F1, M1-L half-cone, and Langley lenticular bodies.

    Science.gov (United States)

    1962-01-01

    acquired a Pontiac Catalina convertible with the largest engine available. He took the car to Bill Straup's renowned hot-rod shop near Long Beach for modification. With a special gearbox and racing slicks, the Pontiac could tow the 1,000-pound M2-F1 110 miles per hour in 30 seconds. It proved adequate for the roughly 400 car tows that got the M2-F1 airborne to prove it could fly safely and to train pilots before they were towed behind a C-47 aircraft and released. These initial car-tow tests produced enough flight data about the M2-F1 to proceed with flights behind the C-47 tow plane at greater altitudes. The C-47 took the craft to an altitude of 12,000 where free flights back to Rogers Dry Lake began. Pilot for the first series of flights of the M2-F1 was NASA research pilot Milt Thompson. Typical glide flights with the M2-F1 lasted about two minutes and reached speeds of 110 to l20 mph. A small solid landing rocket, referred to as the 'instant L/D rocket,' was installed in the rear base of the M2-F1. This rocket, which could be ignited by the pilot, provided about 250 pounds of thrust for about 10 seconds. The rocket could be used to extend the flight time near landing if needed. More than 400 ground tows and 77 aircraft tow flights were carried out with the M2-F1. The success of Dryden's M2-F1 program led to NASA's development and construction of two heavyweight lifting bodies based on studies at NASA's Ames and Langley research centers--the M2-F2 and the HL-10, both built by the Northrop Corporation, and the U.S. Air Force's X-24 program, with an X-24A and -B built by Martin. The Lifting Body program also heavily influenced the Space Shuttle program. The M2-F1 program demonstrated the feasibility of the lifting body concept for horizontal landings of atmospheric entry vehicles. It also demonstrated a procurement and management concept for prototype flight test vehicles that produced rapid results at very low cost (approximately $50,000, excluding salaries of government

  16. Phenotypic Data Collection and Sample Preparation for Genomics of Wood Formation and Cellulosic Biomass Traits in Sunflower: Ames, IA location.

    Energy Technology Data Exchange (ETDEWEB)

    Marek, Laura F.

    2011-06-17

    Three fields were planted in Ames in 2010, two association mapping fields, N3 and A, and a recombinant inbred line field, N13. Phenotype data and images were transferred to UGA to support genetic and genomic analyses of woody biomass-related traits.

  17. Prominent transverse flow of clusters in stopped Au(150AMeV)+Au reactions

    International Nuclear Information System (INIS)

    Stopped Au(150AMeV)+Au collisions have been measured with the FOPI-Detector at GSI by imposing an upper limit on the ratio of the global longitudinal momentum to the collected charge within an event. The ejectiles, in particular those with Z>3, have a rapidity close to mid-rapidity and exhibit angular distributions in the centre-of-mass strongly peaking around 90 thus suggesting an enhancement of the flow in the transverse direction. Fits to the data and comparisons with QMD calculations indicate an averaged collective velocity in the transverse direction equal to 0.12c. Significance of the determined velocity and temperature values is discussed. ((orig.))

  18. How to write an educational research grant: AMEE Guide No. 101.

    Science.gov (United States)

    Blanco, Maria A; Gruppen, Larry D; Artino, Anthony R; Uijtdehaage, Sebastian; Szauter, Karen; Durning, Steven J

    2016-01-01

    Writing an educational research grant in health profession education is challenging, not only for those doing it for the first time but also for more experienced scholars. The intensity of the competition, the peculiarities of the grant format, the risk of rejection, and the time required are among the many obstacles that can prevent educational researchers with interesting and important ideas from writing a grant, that could provide the funding needed to turn their scholarly ideas into reality. The aim of this AMEE Guide is to clarify the grant-writing process by (a) explaining the mechanics and structure of a typical educational research grant proposal, and (b) sharing tips and strategies for making the process more manageable. PMID:26524428

  19. New Diagnostic, Launch and Model Control Techniques in the NASA Ames HFFAF Ballistic Range

    Science.gov (United States)

    Bogdanoff, David W.

    2012-01-01

    This report presents new diagnostic, launch and model control techniques used in the NASA Ames HFFAF ballistic range. High speed movies were used to view the sabot separation process and the passage of the model through the model splap paper. Cavities in the rear of the sabot, to catch the muzzle blast of the gun, were used to control sabot finger separation angles and distances. Inserts were installed in the powder chamber to greatly reduce the ullage volume (empty space) in the chamber. This resulted in much more complete and repeatable combustion of the powder and hence, in much more repeatable muzzle velocities. Sheets of paper or cardstock, impacting one half of the model, were used to control the amplitudes of the model pitch oscillations.

  20. Development of Implicit Methods in CFD NASA Ames Research Center 1970's - 1980's

    Science.gov (United States)

    Pulliam, Thomas H.

    2010-01-01

    The focus here is on the early development (mid 1970's-1980's) at NASA Ames Research Center of implicit methods in Computational Fluid Dynamics (CFD). A class of implicit finite difference schemes of the Beam and Warming approximate factorization type will be addressed. The emphasis will be on the Euler equations. A review of material pertinent to the solution of the Euler equations within the framework of implicit methods will be presented. The eigensystem of the equations will be used extensively in developing a framework for various methods applied to the Euler equations. The development and analysis of various aspects of this class of schemes will be given along with the motivations behind many of the choices. Various acceleration and efficiency modifications such as matrix reduction, diagonalization and flux split schemes will be presented.

  1. Enthalpy By Energy Balance for Aerodynamic Heating Facility at NASA Ames Research Center Arc Jet Complex

    Science.gov (United States)

    Hightower, T. Mark; MacDonald, Christine L.; Martinez, Edward R.; Balboni, John A.; Anderson, Karl F.; Arnold, Jim O. (Technical Monitor)

    2002-01-01

    The NASA Ames Research Center (ARC) Arc Jet Facilities' Aerodynamic Heating Facility (AHF) has been instrumented for the Enthalpy By Energy Balance (EB2) method. Diagnostic EB2 data is routinely taken for all AHF runs. This paper provides an overview of the EB2 method implemented in the AHF. The chief advantage of the AHF implementation over earlier versions is the non-intrusiveness of the instruments used. For example, to measure the change in cooling water temperature, thin film 1000 ohm Resistance Temperature Detectors (RTDs) are used with an Anderson Current Loop (ACL) as the signal conditioner. The ACL with 1000 ohm RTDs allows for very sensitive measurement of the increase in temperature (Delta T) of the cooling water to the arc heater, which is a critical element of the EB2 method. Cooling water flow rates are measured with non-intrusive ultrasonic flow meters.

  2. Stationary Wave Activity Simulated by the NASA Ames MGCM Incorporating New MOLA Topography Data

    Science.gov (United States)

    Bridger, A. F. C.; Hollingsworth, J. L.; Haberle, R. M.; Schaeffer, J.

    1999-01-01

    Annual simulations of Mars' atmosphere have been conducted with the NASA Ames Mars General Circulation Model (MGCM) using the newly-acquired MOLA topography data. The data is provided at 1 x 1 deg resolution, and is used by the MGCM at 7.5 x 9 deg resolution. The vertical domain in the simulations reported here extends to around 80 km. Simulated stationary wave activity is examined in each hemisphere as a function of season (at every 30 deg of Ls), dust loading (dust visible opacities of 0.3, 1, and 3), and topography (comparing results with MOLA vs. Smith-Zuber topography). Additional information is contained in the original extended abstract.

  3. Wind-tunnel tests of the XV-15 tilt rotor aircraft

    Science.gov (United States)

    Weiberg, J. A.; Maisel, M. D.

    1980-01-01

    The XV-15 aircraft was tested in the Ames 40 by 80 Foot Wind Tunnel for preliminary evaluation of aerodynamic and aeroelastic characteristics prior to flight. The tests were undertaken to investigate the aircraft performance, stability, control and structural loads for flight modes from helicopter through transition and airplane mode up to the tunnel capability of 170 knots. Results from these tests are presented.

  4. Prevention of Neuromusculoskeletal Frailty in Slow-Aging Ames Dwarf Mice: Longitudinal Investigation of Interaction of Longevity Genes and Caloric Restriction

    OpenAIRE

    Arum, Oge; Rasche, Zachary Andrew; Rickman, Dustin John; Bartke, Andrzej

    2013-01-01

    Ames dwarf (Prop1 df/df ) mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR) has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice. Our study objective was to determine whether Ames dwarfism or CR influence neuromusculoskeletal function in middle-aged (82 ± 12 weeks old) or old (128 ± 14 w.o.) mice. At the examined ages, strength was improved by dwarfism, CR, and d...

  5. A Summary of the Experimental Results for a Generic Tractor-Trailer in the Ames Research Center 7- by 10-Foot and 12-Foot Wind Tunnels

    Science.gov (United States)

    Storms, Bruce L.; Satran, Dale R.; Heineck, James T.; Walker, Stephen M.

    2006-01-01

    Experimental measurements of a generic tractor-trailer were obtained in two wind tunnels at Ames Research Center. After a preliminary study at atmospheric conditions in the 7- by 10-Foot Wind Tunnel, additional testing was conducted at Reynolds numbers corresponding to full-scale highway speeds in the 12-Foot Pressure Wind Tunnel. To facilitate computational modeling, the 1:8-scale geometry, designated the Generic Conventional Model, included a simplified underbody and omitted many small-scale details. The measurements included overall and component forces and moments, static and dynamic surface pressures, and three-component particle image velocimetry. This summary report highlights the effects of numerous drag reduction concepts and provides details of the model installation in both wind tunnels. To provide a basis for comparison, the wind-averaged drag coefficient was tabulated for all configurations tested. Relative to the baseline configuration representative of a modern class-8 tractor-trailer, the most effective concepts were the trailer base flaps and trailer belly box providing a drag-coefficient reduction of 0.0855 and 0.0494, respectively. Trailer side skirts were less effective yielding a drag reduction of 0.0260. The database of this experimental effort is publicly available for further analysis.

  6. Anthrax Vaccine Antigen-Adjuvant Formulations Completely Protect New Zealand White Rabbits against Challenge with Bacillus anthracis Ames Strain Spores

    OpenAIRE

    Peachman, Kristina K.; Li, Qin; Matyas, Gary R.; Shivachandra, Sathish B.; Lovchik, Julie; Lyons, Rick C.; Alving, Carl R; Rao, Venigalla B.; Rao, Mangala

    2012-01-01

    In an effort to develop an improved anthrax vaccine that shows high potency, five different anthrax protective antigen (PA)-adjuvant vaccine formulations that were previously found to be efficacious in a nonhuman primate model were evaluated for their efficacy in a rabbit pulmonary challenge model using Bacillus anthracis Ames strain spores. The vaccine formulations include PA adsorbed to Alhydrogel, PA encapsulated in liposomes containing monophosphoryl lipid A, stable liposomal PA oil-in-wa...

  7. Quest for toroidal freeze-out configuration in the central 197Au + 197Au collisions at 23 AMeV

    Directory of Open Access Journals (Sweden)

    Najman R.

    2015-01-01

    Full Text Available We present the results of the experiment performed by the CHIMERA collaboration with the 4π CHIMERA array, for the system 197Au+197Au at 23 AMeV. The experimental data are compared with ETNA and QMD model predictions. Efficiency factor is used as an indication of the formation of an exotic freeze-out configuration. Comparison between experimental data and model predictions may indicate the formation of flat/toroidal nuclear systems.

  8. The AMeX method: a multipurpose tissue-processing and paraffin-embedding method. II. Extraction of spooled DNA and its application to Southern blot hybridization analysis.

    Science.gov (United States)

    Sato, Y.; Mukai, K.; Matsuno, Y.; Furuya, S.; Kagami, Y.; Miwa, M.; Shimosato, Y.

    1990-01-01

    In our previous report, we described a new fixation and paraffin-embedding method (the AMeX method) that preserves many of the antigens that are normally destroyed by routine formalin fixation. The current study was conducted to examine the preservation of high-molecular-weight DNA in tissues processed by this method. DNA was extracted from AMeX-processed tissue sections after deparaffinization by the same method as that used to extract DNA from fresh tissues. The total amounts of DNA extracted from 10 mg each in wet weight of AMeX-processed and fresh mouse liver tissues were identical. In tissues of malignant lymphoma, the total amount of spooled DNA extracted from 50 sections, each 20 microns thick, was about 8 micrograms/mm2. The electrophoretic pattern of DNA digested with restriction endonucleases on agarose gel from AMeX-processed tissue sections did not differ from that of fresh materials. Southern blot hybridization analysis also revealed that the mobility of specific DNA fragments was identical for AMeX-processed and fresh tissues. The AMeX method was thus proved to be a versatile multipurpose tissue-processing procedure, which is expected to provide important information regarding the correlation between morphology, phenotypic expression, and gene alteration. Images Figure 3 Figure 4 Figure 5A Figure 5B PMID:2407122

  9. Long-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure.

    Science.gov (United States)

    Hill, Cristal M; Fang, Yimin; Miquet, Johanna G; Sun, Liou Y; Masternak, Michal M; Bartke, Andrzej

    2016-06-01

    Growth hormone (GH) signaling stimulates the production of IGF-1; however, increased GH signaling may induce insulin resistance and can reduce life expectancy in both mice and humans. Interestingly, disruption of GH signaling by reducing plasma GH levels significantly improves health span and extends lifespan in mice, as observed in Ames dwarf mice. In addition, these mice have increased adiposity, yet are more insulin sensitive compared to control mice. Metabolic stressors such as high-fat diet (HFD) promote obesity and may alter longevity through the GH signaling pathway. Therefore, our objective was to investigate the effects of a HFD (metabolic stressor) on genetic mechanisms that regulate metabolism during aging. We show that Ames dwarf mice fed HFD for 12 weeks had an increase in subcutaneous and visceral adiposity as a result of diet-induced obesity, yet are more insulin sensitive and have higher levels of adiponectin compared to control mice fed HFD. Furthermore, energy expenditure was higher in Ames dwarf mice fed HFD than in control mice fed HFD. Additionally, we show that transplant of epididymal white adipose tissue (eWAT) from Ames dwarf mice fed HFD into control mice fed HFD improves their insulin sensitivity. We conclude that Ames dwarf mice are resistant to the detrimental metabolic effects of HFD and that visceral adipose tissue of Ames dwarf mice improves insulin sensitivity in control mice fed HFD. PMID:26990883

  10. Ames expedited site characterization demonstration at the former manufactured gas plant site, Marshalltown, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    Bevolo, A.J.; Kjartanson, B.H.; Wonder, J.D.

    1996-03-01

    The goal of the Ames Expedited Site Characterization (ESC) project is to evaluate and promote both innovative technologies (IT) and state-of-the-practice technologies (SOPT) for site characterization and monitoring. In April and May 1994, the ESC project conducted site characterization, technology comparison, and stakeholder demonstration activities at a former manufactured gas plant (FMGP) owned by Iowa Electric Services (IES) Utilities, Inc., in Marshalltown, Iowa. Three areas of technology were fielded at the Marshalltown FMGP site: geophysical, analytical and data integration. The geophysical technologies are designed to assess the subsurface geological conditions so that the location, fate and transport of the target contaminants may be assessed and forecasted. The analytical technologies/methods are designed to detect and quantify the target contaminants. The data integration technology area consists of hardware and software systems designed to integrate all the site information compiled and collected into a conceptual site model on a daily basis at the site; this conceptual model then becomes the decision-support tool. Simultaneous fielding of different methods within each of the three areas of technology provided data for direct comparison of the technologies fielded, both SOPT and IT. This document reports the results of the site characterization, technology comparison, and ESC demonstration activities associated with the Marshalltown FMGP site. 124 figs., 27 tabs.

  11. Ames expedited site characterization demonstration at the former manufactured gas plant site, Marshalltown, Iowa

    International Nuclear Information System (INIS)

    The goal of the Ames Expedited Site Characterization (ESC) project is to evaluate and promote both innovative technologies (IT) and state-of-the-practice technologies (SOPT) for site characterization and monitoring. In April and May 1994, the ESC project conducted site characterization, technology comparison, and stakeholder demonstration activities at a former manufactured gas plant (FMGP) owned by Iowa Electric Services (IES) Utilities, Inc., in Marshalltown, Iowa. Three areas of technology were fielded at the Marshalltown FMGP site: geophysical, analytical and data integration. The geophysical technologies are designed to assess the subsurface geological conditions so that the location, fate and transport of the target contaminants may be assessed and forecasted. The analytical technologies/methods are designed to detect and quantify the target contaminants. The data integration technology area consists of hardware and software systems designed to integrate all the site information compiled and collected into a conceptual site model on a daily basis at the site; this conceptual model then becomes the decision-support tool. Simultaneous fielding of different methods within each of the three areas of technology provided data for direct comparison of the technologies fielded, both SOPT and IT. This document reports the results of the site characterization, technology comparison, and ESC demonstration activities associated with the Marshalltown FMGP site. 124 figs., 27 tabs

  12. Radiation-induced mutagenicity and lethality in Ames tester strains of Salmonella

    International Nuclear Information System (INIS)

    Mutation and killing induced by X radiation and 60Co γ radiation were studied in six different histidine-requiring auxotrophs of Salmonella typhimurium. Strain TA100, which is sensitive to base-pair substitutions, and strains TA2637 and TA98, which are sensitive to frameshifts, carry the pKM101 plasmid and exhibit significantly higher radiation-induced mutations compared to their plasmidless parent strains TA1535, TA1537, and TA1538, respectively. Among the plasmid-containing strains, TA98 and TA2637 are much more sensitive to the mutagenic action of radiation than is TA100 based on a comparison with their respective spontaneous mutation rates; however, no uniformity was observed in the responses of the strains to the lethal action of ionizing radiation. The following conclusions are consistent with these observations: (1) the standard Ames Salmonella assay correctly identifies ionizing radiation as a mutagenic agent; (2) frameshift-sensitive parent strains are more sensitive to the mutagenic effects of ionizing radiation than is the only strain studied that is sensitive to base-pair substitutions; and (3) enhancement of mutagenesis and survival is related to plasmid-mediated repair of DNA damage induced by ionizing radiation and does not involve damage induced by Cerenkov-generated uv radiation which is negligible for our irradiation conditions

  13. Emission Spectroscopy and Radiometric Measurements in the NASA Ames IHF Arc Jet Facility

    Science.gov (United States)

    Winter, Michael W.; Raiche, George A.; Prabhu, Dinesh K.

    2012-01-01

    Plasma diagnostic measurement campaigns in the NASA Ames Interaction Heating Facility (IHF) have been conducted over the last several years with a view towards characterizing the flow in the arc jet facility by providing data necessary for modeling and simulation. Optical emission spectroscopy has been used in the plenum and in the free jet of the nozzle. Radiation incident over a probe surface has also been measured using radiometry. Plenum measurements have shown distinct radial profiles of temperature over a range of operating conditions. For cases where large amounts of cold air are added radially to the main arc-heated stream, the temperature profiles are higher by as much as 1500 K than the profiles assumed in flow simulations. Optical measurements perpendicular to the flow direction in the free jet showed significant contributions to the molecule emission through inverse pre-dissociation, thus allowing determination of atom number densities from molecular emission. This has been preliminarily demonstrated with the N2 1st Positive System. Despite the use of older rate coefficients, the resulting atom densities are reasonable and surprisingly close to flow predictions.

  14. Flow Property Measurement Using Laser-Induced Fluorescence in the NASA Ames Interaction Heating Facility

    Science.gov (United States)

    Grinstead, Jay Henderson; Porter, Barry J.; Carballo, Julio Enrique

    2011-01-01

    The spectroscopic diagnostic technique of two photon absorption laser-induced fluorescence (TALIF) of atomic species has been applied to single-point measurements of velocity and static temperature in the NASA Ames Interaction Heating Facility (IHF) arc jet. Excitation spectra of atomic oxygen and nitrogen were recorded while scanning a tunable dye laser over the absorption feature. Thirty excitation spectra were acquired during 8 arc jet runs at two facility operating conditions; the number of scans per run varied between 2 and 6. Curve fits to the spectra were analyzed to recover their Doppler shifts and widths, from which the flow velocities and static temperatures, respectively, were determined. An increase in the number of independent flow property pairs from each as-measured scan was obtained by extracting multiple lower-resolution scans. The larger population sample size enabled the mean property values and their uncertainties for each run to be characterized with greater confidence. The average plus or minus 2 sigma uncertainties in the mean velocities and temperatures for all 8 runs were plus or minus 1.4% and plus or minus 11%, respectively.

  15. Training for life science experiments in space at the NASA Ames Research Center

    Science.gov (United States)

    Rodrigues, Annette T.; Maese, A. Christopher

    1993-01-01

    As this country prepares for exploration to other planets, the need to understand the affects of long duration exposure to microgravity is evident. The National Aeronautics and Space Administration (NASA) Ames Research Center's Space Life Sciences Payloads Office is responsible for a number of non-human life sciences payloads on NASA's Space Shuttle's Spacelab. Included in this responsibility is the training of those individuals who will be conducting the experiments during flight, the astronauts. Preparing a crew to conduct such experiments requires training protocols that build on simple tasks. Once a defined degree of performance proficiency is met for each task, these tasks are combined to increase the complexity of the activities. As tasks are combined into in-flight operations, they are subjected to time constraints and the crew enhances their skills through repetition. The science objectives must be completely understood by the crew and are critical to the overall training program. Completion of the in-flight activities is proof of success. Because the crew is exposed to the background of early research and plans for post-flight analyses, they have a vested interest in the flight activities. The salient features of this training approach is that it allows for flexibility in implementation, consideration of individual differences, and a greater ability to retain experiment information. This training approach offers another effective alternative training tool to existing methodologies.

  16. Effects of reaction control system jet simulation on the stability and control characteristics of a 0.015-scale space shuttle orbiter model in the Ames Research Center 3.5-foot hypersonic wind tunnel

    Science.gov (United States)

    Dziubala, T. J.; Marroquin, J.; Cleary, J. W.; Mellenthin, J. A.

    1973-01-01

    An experimental investigation was performed in the Ames Research Center 3.5-Foot Hypersonic Wind Tunnel to obtain detailed effects which interactions between the RCS jet flow field and the local orbiter flow field have on orbiter hypersonic stability and control characteristics. Six-component force data were obtained through an angle-of-attack range of 15 to 35 deg with 0 deg angle of sideslip. The test was conducted with yaw, pitch and roll jet simulation at a free-stream Mach number of 10.3. These data simulate two SSV reentry flight conditions at Mach numbers of 28.3 and 10.3. Fuselage base pressures and pressures on the nonmetric RCS pods were obtained in addition to the basic force measurements. Model 42-0 was used for these tests.

  17. Aeroacoustic Characterization of the NASA Ames Experimental Aero-Physics Branch 32- by 48-Inch Subsonic Wind Tunnel with a 24-Element Phased Microphone Array

    Science.gov (United States)

    Costanza, Bryan T.; Horne, William C.; Schery, S. D.; Babb, Alex T.

    2011-01-01

    The Aero-Physics Branch at NASA Ames Research Center utilizes a 32- by 48-inch subsonic wind tunnel for aerodynamics research. The feasibility of acquiring acoustic measurements with a phased microphone array was recently explored. Acoustic characterization of the wind tunnel was carried out with a floor-mounted 24-element array and two ceiling-mounted speakers. The minimum speaker level for accurate level measurement was evaluated for various tunnel speeds up to a Mach number of 0.15 and streamwise speaker locations. A variety of post-processing procedures, including conventional beamforming and deconvolutional processing such as TIDY, were used. The speaker measurements, with and without flow, were used to compare actual versus simulated in-flow speaker calibrations. Data for wind-off speaker sound and wind-on tunnel background noise were found valuable for predicting sound levels for which the speakers were detectable when the wind was on. Speaker sources were detectable 2 - 10 dB below the peak background noise level with conventional data processing. The effectiveness of background noise cross-spectral matrix subtraction was assessed and found to improve the detectability of test sound sources by approximately 10 dB over a wide frequency range.

  18. Residents as teachers: Near peer learning in clinical work settings: AMEE Guide No. 106.

    Science.gov (United States)

    Ramani, Subha; Mann, Karen; Taylor, David; Thampy, Harish

    2016-07-01

    This AMEE Guide provides a framework to guide medical educators engaged in the design and implementation of "Resident as Teacher" programs. The suggested approaches are based on established models of program development: the Program Logic model to guide program design, the Dundee three-circle model to inform a systematic approach to planning educational content and the Kirkpatrick pyramid, which forms the backbone of program evaluation. The Guide provides an overview of Resident as Teacher curricula, their benefits and impact, from existing literature supplemented by insights from the authors' own experiences, all of whom are engaged in teaching initiatives at their own institutions. A conceptual description of the Program Logic model is provided, a model that highlights an outcomes-based curricular design. Examples of activities under each step of this model are described, which would allow educational leaders to structure their own program based on the scope, context, institutional needs and resources available. Emphasis is placed on a modular curricular format to not only enhance the teaching skills of residents, but also enable development of future career educators, scholars and leaders. Application of the Dundee three-circle model is illustrated to allow for a flexible curricular design that can cater to varying levels of educational needs and interests. In addition, practical advice is provided on robust assessment of outcomes, both assessment of participants and program evaluation. Finally, the authors highlight the need for congruence between the formal and hidden curriculum through explicit recognition of the value of teaching by institutions, support for development of teaching programs, encouragement of evidence-based approach to education and rewards for all levels of teachers. PMID:27071739

  19. Multiyear Simulations of the Martian Water Cycle with the Ames General Circulation Model

    Science.gov (United States)

    Haberle, R. M.; Schaeffer, J. R.; Nelli, S. M.; Murphy, J. R.

    2003-01-01

    Mars atmosphere is carbon dioxide dominated with non-negligible amounts of water vapor and suspended dust particles. The atmospheric dust plays an important role in the heating and cooling of the planet through absorption and emission of radiation. Small dust particles can potentially be carried to great altitudes and affect the temperatures there. Water vapor condensing onto the dust grains can affect the radiative properties of both, as well as their vertical extent. The condensation of water onto a dust grain will change the grain s fall speed and diminish the possibility of dust obtaining high altitudes. In this capacity, water becomes a controlling agent with regard to the vertical distribution of dust. Similarly, the atmosphere s water vapor holding capacity is affected by the amount of dust in the atmosphere. Dust is an excellent green house catalyst; it raises the temperature of the atmosphere, and thus, its water vapor holding capacity. There is, therefore, a potentially significant interplay between the Martian dust and water cycles. Previous research done using global, 3-D computer modeling to better understand the Martian atmosphere treat the dust and the water cycles as two separate and independent processes. The existing Ames numerical model will be employed to simulate the relationship between the Martian dust and water cycles by actually coupling the two cycles. Water will condense onto the dust, allowing the particle's radiative characteristics, fall speeds, and as a result, their vertical distribution to change. Data obtained from the Viking, Mars Pathfinder, and especially the Mars Global Surveyor missions will be used to determine the accuracy of the model results.

  20. Multi-Mission Suitability of the NASA Ames Modular Common Bus

    Science.gov (United States)

    Tietz, Sascha; Bell, James H.; Hine, Butler

    2009-01-01

    The obvious advantages of small spacecraft - their lower cost structure and the rapid development schedule - have enabled a large number of missions in the past. However, most of these missions have been focused on Earth observation from low Earth orbits. In 2006, the Small Spacecraft Division at the NASA Ames Research Center began the development of the Modular Common Bus, a spacecraft capable of delivering scientifically and technically useful payloads to a variety of destinations within 0.1 AU around the Earth. The core technologies used in the Common Bus design are a composite structure with body-mounted solar cells, an integrated avionics unit, and a high performance bipropellant propulsion system. Due to its modular approach, the Common Bus can be adapted to fit specific mission needs while still using a standardized and qualified set of components. Additionally a number of low cost launch vehicles are supported, resulting in overall mission costs of around $150M including the launch vehicle but excluding the science payloads. This significant reduction in cost and the shorter development time would enable NASA to conduct more frequent exploration missions within its budget and timeframe constraints, compared to the status quo. In this paper the suitability of the Common Spacecraft Bus for four different exploration scenarios is analyzed. These scenarios include a lunar orbiter, a lunar lander, a mission to a Sun-Earth Libration Point, and a rendezvous mission to a Near Earth Object. For each scenario, a preliminary design reference mission is developed and key design parameters for the spacecraft are determined.

  1. Results of toxicological testing of Jefferson Parish pilot plant samples.

    OpenAIRE

    Miller, R.G.; Kopfler, F C; Condie, L W; Pereira, M. A.; Meier, J. R.; Ringhand, H P; Robinson, M; Casto, B. C.

    1986-01-01

    Five toxicological tests were performed using concentrated drinking water samples collected at a pilot-scale drinking water treatment plant that had streams treated with different disinfectants (no disinfectant, ozone, chlorine dioxide, monochloramine, or chlorine) before treatment with granular activated carbon (GAC). The toxicological tests used in this study were the Ames Salmonella assay, a subchronic in vivo toxicity assay in mice, the SENCAR mouse skin initiation-promotion assay, a rat ...

  2. Evaluación del D-004 en el Ensayo de Ames por incorporación directa a placa

    OpenAIRE

    Gutiérrez Martínez, A.; Marrero Cofiño, G.; Gámez Menéndez, R.; I. Fernández; Curveco Sánchez, D.; H García Cambián

    2005-01-01

    El D-004 es un extracto lipídico obtenido del fruto de la palma real (Roystonea regia) (Arecaceae) que consiste en una mezcla reproducible de ácidos grasos, en la cual el ácido oleico, el laurico y el palmítico son los más abundantes. El tratamiento oral con D-004 inhibe significativamente la hiperplasia prostática (HP) inducida por testosterona en roedores. El objetivo de este trabajo fue investigar si el D-004 induce mutaciones génicas puntuales en el ensayo de Ames por incorporación direct...

  3. Office of Health and Environmental Research. Quarterly report, April 1, 1979-June 30, 1979. [Ames Municipal Solid Waste Recovery System

    Energy Technology Data Exchange (ETDEWEB)

    Fassel, V.A.

    1979-10-01

    Progress in the following areas of research reported: characterization of organic pollutants emitted by fossil fuel processing and energy generating plants; environmental effects of using municipal solid wastes as a supplementary fuel; microbiological air quality at the Ames Municipal Solid Waste Recovery System; solid waste to methane environmental study; x-ray and ultraviolet excited optical luminescence (SEOL, UVEOL) of carcinogens - analytical possibilities; laser pumped luminescence (LPL) spectroscopy; and multielement characterization of air particulates. New laser-based methods for the determination of organic pollutants via fluorescence are discussed. (JGB)

  4. A perspective on 15 years of proof-of-concept aircraft development and flight research at Ames-Moffett by the Rotorcraft and Powered-Lift Flight Projects Division, 1970-1985

    Science.gov (United States)

    Few, David D.

    1987-01-01

    A proof-of-concept (POC) aircraft is defined and the concept of interest described for each of the six aircraft developed by the Ames-Moffet Rotorcraft and Powered-Lift Flight Projects Division from 1970 through 1985; namely, the OV-10, the C-8A Augmentor Wing, the Quiet Short-Haul Research Aircraft (QSRA), the XV-15 Tilt Rotor Research Aircraft (TRRA), the Rotor Systems Research Aircraft (RSRA)-compound, and the yet-to-fly RSRA/X-Wing Aircraft. The program/project chronology and most noteworthy features of the concepts are reviewed. The paper discusses the significance of each concept and the project demonstrating it; it briefly looks at what concepts are on the horizon as potential POC research aircraft and emphasizes that no significant advanced concept in aviation technology has ever been accepted by civilian or military users without first completing a demonstration through flight testing.

  5. An Overview of the NASA Ames Millimeter-Wave Thermal Launch System

    Science.gov (United States)

    Murakami, David

    2012-01-01

    The Millimeter-Wave Thermal Launch System (MTLS) is a beamed-energy propulsion concept being designed at NASA Ames Research Center. This effort is in response to the NASA Office of the Chief Technologist s announcement of the Ride the Light program. Our objective is to produce a design that goes beyond the feasibility analysis level of previous studies and provides a solid foundation for low cost access to space. The MTLS is designed to place a 500 lb payload into Low Earth Orbit (LEO) two times a day. This frequent launch, small payload niche is well suited for the particular advantages and constraints of beamed-energy propulsion, and has the potential to drastically increase access to space by reducing the cost per kilogram of placing payloads into LEO. This paper summarizes the findings of the MTLS study. The chemical rocket engine is in principle a simple device. It acts by releasing the chemical energy stored in propellants such as hydrogen and oxygen through combustion, then converting that thermal energy into kinetic energy by expansion through a nozzle. As such, it is fundamentally limited by the energy released in combustion reactions and the molecular weight of the products of those reactions. The highest performing conventional propellant combination, liquid oxygen and liquid hydrogen, can produce vacuum specific impulses of around 450 seconds. The design space of current launch vehicles (which tend to be large, multi-stage, and expendable) are defined by these limitations. An entirely new approach may be necessary in order to enable future launch vehicles of radically improved capabilities. Beamed-energy propulsion (BEP) is an alternative approach that bypasses the energy limitations of chemical propulsion. Instead of relying on a chemical reaction as the energy source, it is supplied externally via a beam of electromagnetic energy produced on the ground. In the concept examined in the MTLS, this energy is absorbed by a heat exchanger which then

  6. Effect of Methyl tert-Butyl Ether in Standard Tests for Mutagenicity and Environmental Toxicity

    Czech Academy of Sciences Publication Activity Database

    Vosáhlíková, M.; Cajthaml, Tomáš; Demnerová, K.; Pazlarová, Jarmila

    2006-01-01

    Roč. 21, č. 6 (2006), s. 599-605. ISSN 1520-4081 Institutional research plan: CEZ:AV0Z50200510 Keywords : toxicity * mtbe * ames test Subject RIV: EE - Microbiology, Virology Impact factor: 1.582, year: 2006

  7. Final work plan: Expedited Site Characterization of the IES Industries, Inc., Site at Marshalltown, Iowa. Ames Expedited Site Characterization Project, Version 1.0

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-04

    The overall goal of the Ames Laboratory Expedited Site Characterization (ESC) project is to evaluate and promote both innovative and state-of-the-practice site characterization and/or monitoring technologies. This will be accomplished by fielding both types of technologies together in the context of an expedited site characterization. The first site will be at a former manufactured gas plant (FMGP) in Marshalltown, Iowa. The project will field three areas of technology: geophysical, analytical, and data fusion. Geophysical technologies are designed to understand the subsurface geology to help predict fate and transport of the target contaminants. Analytical technologies/methods are designed to detect and quantify the target contaminants. Data fusion technology consists of software systems designed to rapidly integrate or fuse all site information into a conceptual site model that then becomes the decision making tool for the site team to plan subsequent sampling activity. Not all of the contaminants present can be located at the action level. Polynuclear aromatic hydrocarbons (PAHs) are the signature organics associated with the coal tar activities that took place at the site. As a result, PAHs were selected as the target compounds. Screening analytical instruments and nonintrusive geophysical techniques will be fielded to qualitatively map the spatial contaminant distribution. Soil gas surveys, immunoassay testing (IMA), innovative optical techniques, and passive organic sorbent sensors will be deployed along with the geophysical methods. Gas chromatography/mass spectrometry (GC/MS) instruments and a cone penetrometer system equipped with a laser-induced fluorescence (LIF) probe will quantitatively map the action level edges of the PAH plume(s). Samples will be taken both by the cone penetrometer test system (CPT) and the Geoprobe {reg_sign} sampler system.

  8. The AMeX method: a multipurpose tissue-processing and paraffin-embedding method. Extraction of protein and application to immunoblotting.

    OpenAIRE

    Y. Sato; Mukai, K.; Furuya, S; Kameya, T.; Hirohashi, S

    1992-01-01

    The authors have previously reported a new fixation and paraffin-embedding method (the AMeX method), which preserves many antigens as well as high molecular-weight DNA and RNA that are normally destroyed by the routine formalin fixation and paraffin-embedding process. In the present study, the authors analyzed the preservation of protein suitable for sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting in tissue fixed by the AMeX method. The method used for ...

  9. The AMeX method: a multipurpose tissue-processing and paraffin-embedding method. II. Extraction of spooled DNA and its application to Southern blot hybridization analysis.

    OpenAIRE

    Y. Sato; Mukai, K.; Matsuno, Y.; Furuya, S; Kagami, Y; Miwa, M; Shimosato, Y.

    1990-01-01

    In our previous report, we described a new fixation and paraffin-embedding method (the AMeX method) that preserves many of the antigens that are normally destroyed by routine formalin fixation. The current study was conducted to examine the preservation of high-molecular-weight DNA in tissues processed by this method. DNA was extracted from AMeX-processed tissue sections after deparaffinization by the same method as that used to extract DNA from fresh tissues. The total amounts of DNA extract...

  10. Measurement of 100 B. anthracis Ames spores within 15 minutes by SERS at the US Army Edgewood Chemical Biological Ctr.

    Science.gov (United States)

    Farquharson, Stuart; Shende, Chetan; Smith, Wayne; Huang, Hermes; Sperry, Jay; Sickler, Todd; Prugh, Amber; Guicheteau, Jason

    2014-05-01

    Since the distribution of Bacillus anthracis-Ames spores through the US Postal System, there has been a persistent fear that biological warfare agents will be used by terrorists against our military abroad and our civilians at home. While there has been substantial effort since the anthrax attack of 2001 to develop analyzers to detect this and other biological warfare agents, the analyzers remain either too slow, lack sensitivity, produce high false-positive rates, or cannot be fielded. In an effort to overcome these limitations we have been developing a surface-enhanced Raman spectroscopy system. Here we describe the use of silver nanoparticles functionalized with a short peptide to selectively capture Bacillus anthracis spores and produce SER scattering. Specifically, measurements of 100 B. anthracis-Ames spores/mL in ~25 minutes performed at the US Army's Edgewood Chemical Biological Center are presented. The measurements provide a basis for the development of systems that can detect spores collected from the air or water supplies with the potential of saving lives during a biological warfare attack.

  11. The Center-TRACON Automation System: Simulation and field testing

    Science.gov (United States)

    Denery, Dallas G.; Erzberger, Heinz

    1995-01-01

    A new concept for air traffic management in the terminal area, implemented as the Center-TRACON Automation System, has been under development at NASA Ames in a cooperative program with the FAA since 1991. The development has been strongly influenced by concurrent simulation and field site evaluations. The role of simulation and field activities in the development process will be discussed. Results of recent simulation and field tests will be presented.

  12. AMES, NESC and ENIQ: European networks in the field of structural integrity involving NDE and inspection effectiveness assessment

    International Nuclear Information System (INIS)

    Three European networks on structural integrity aspects of ageing nuclear components are presently managed by the Institute for Advanced Materials of the Joint Research Centre of the European Commission: AMES (Ageing Materials Evaluation and Studies), ENIQ (European Network for Inspection Qualification) and NESC (Network for Evaluating Steel Components). All three networks involve actions, which aim at the effectiveness and reliability assessment of NDE techniques and of inspection procedures: Either for materials damage detection and characterisation or for defect detection and evaluation. This paper is describing very generally the objectives of the three networks and is then concentrating on the results obtained in ENIQ, which are relevant with ISI and regulatory issues. (orig./DGE)

  13. Overview of the Testing of a Small-Scale Proprotor

    Science.gov (United States)

    Young, Larry A.; Yamauchi, Gloria K.; Booth, Earl R., Jr.; Botha, Gavin; Dawson, Seth

    1999-01-01

    This paper presents an overview of results from the wind tunnel test of a 1/4-scale V-22 proprotor in the Duits-Nederlandse Windtunnel (DNW) in The Netherlands. The small-scale proprotor was tested on the isolated rotor configuration of the Tilt Rotor Aeroacoustic Model (TRAM). The test was conducted by a joint team from NASA Ames, NASA Langley, U.S. Army Aeroflightdynamics Directorate, and The Boeing Company. The objective of the test was to acquire a benchmark database for validating aeroacoustic analyses. Representative examples of airloads, acoustics, structural loads, and performance data are provided and discussed.

  14. Design techniques for developing a computerized instrumentation test plan. [for wind tunnel test data acquisition system

    Science.gov (United States)

    Burnett, S. Kay; Forsyth, Theodore J.; Maynard, Everett E.

    1987-01-01

    The development of a computerized instrumentation test plan (ITP) for the NASA/Ames Research Center National Full Scale Aerodynamics Complex (NFAC) is discussed. The objective of the ITP program was to aid the instrumentation engineer in documenting the configuration and calibration of data acquisition systems for a given test at any of four low speed wind tunnel facilities (Outdoor Aerodynamic Research Facility, 7 x 10, 40 x 80, and 80 x 120) at the NFAC. It is noted that automation of the ITP has decreased errors, engineering hours, and setup time while adding a higher level of consistency and traceability.

  15. PLOT3D/AMES, APOLLO UNIX VERSION USING GMR3D (WITHOUT TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  16. PLOT3D/AMES, APOLLO UNIX VERSION USING GMR3D (WITH TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  17. X-Wing RSRA - 80 Knot Taxi Test

    Science.gov (United States)

    1987-01-01

    The Rotor Systems Research Aircraft/X-Wing, a vehicle that was used to demonstrate an advanced rotor/fixed wing concept called X-Wing, is shown here during high-speed taxi tests at NASA's Ames-Dryden Flight Research Facility (later redesignated Dryden Flight Research Center), Edwards, California, on 4 November 1987. During these tests, the vehicle made three taxi tests at speeds of up to 138 knots. On the third run, the RSRA/X-Wing lifted off the runway to a 25-foot height for about 16 seconds. This liftoff maneuver was pre-planned as an aid to evaluations for first flight. At the controls were NASA pilot G. Warren Hall and Sikorsky pilot W. Faull. The unusual aircraft that resulted from the Ames Research Center/Army X-Wing Project was flown at the Ames-Dryden Flight Research Facility (now Dryden Flight Research Center), Edwards, California, beginning in the spring of 1984, with a follow-on program beginning in 1986. The program, was conceived to provide an efficient combination of the vertical lift characteristic of conventional helicopters and the high cruise speed of fixed-wing aircraft. It consisted of a hybrid vehicle called the NASA/Army Rotor Systems Research Aircraft (RSRA), which was equipped with advanced X-wing rotor systems. The program began in the early 1970s to investigate ways to increase the speed of rotor aircraft, as well as their performance, reliability, and safety . It also sought to reduce the noise, vibration, and maintenance costs of helicopters. Sikorsky Aircraft Division of United Technologies Laboratories built two RSRA aircraft. NASA's Langley Research Center, Hampton, Virginia, did some initial testing and transferred the program to Ames Research Center, Mountain View, California, for an extensive flight research program conducted by Ames and the Army. The purpose of the 1984 tests was to demonstrate the fixed-wing capability of the helicopter/airplane hybrid research vehicle and explore its flight envelope and flying qualities. These

  18. Results of screening NCI/NTP nongenotoxic carcinogens and genotoxic noncarcinogens with the k sub e test

    Energy Technology Data Exchange (ETDEWEB)

    Mendelsohn, M.L. (ed.); Bakale, G.; McCreary, R.D.

    1989-01-01

    The interdependence of the electrophilic and carcinogenic properties of chemicals that was demonstrated two decades ago rekindled interest in the somatic mutation theory of carcinogenesis. Interest in this theory grew with the development of a reverse-mutation bacterial assay in the laboratory of B.N. Ames that permitted the mutagenic properties of the chemicals to be determined quickly and yielded results which indicated that carcinogens are mutagens.'' Subsequent validation studies of this bioassay, the Salmonella typhimurium/microsome or Ames test,'' by Ames' group and others provided additional support for the correlation between mutagenicity and carcinogenicity which led to the worldwide deployment of the Ames test in thousands of laboratories and to the development of more than 100 other short-term tests that continue to be used to identify potential carcinogens via various end-points of genotoxicity. This document discusses electrophilicity, mutagenicity, and carcinogenicity relationships as well as carcinogen-screening of chemicals. 28 refs., 4 tabs.

  19. PLOT3D/AMES, GENERIC UNIX VERSION USING DISSPLA (WITHOUT TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  20. PLOT3D/AMES, UNIX SUPERCOMPUTER AND SGI IRIS VERSION (WITHOUT TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  1. PLOT3D/AMES, SGI IRIS VERSION (WITH TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  2. PLOT3D/AMES, UNIX SUPERCOMPUTER AND SGI IRIS VERSION (WITH TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  3. PLOT3D/AMES, SGI IRIS VERSION (WITHOUT TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  4. PLOT3D/AMES, DEC VAX VMS VERSION USING DISSPLA (WITH TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  5. PLOT3D/AMES, GENERIC UNIX VERSION USING DISSPLA (WITH TURB3D)

    Science.gov (United States)

    Buning, P.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  6. PLOT3D/AMES, DEC VAX VMS VERSION USING DISSPLA (WITHOUT TURB3D)

    Science.gov (United States)

    Buning, P. G.

    1994-01-01

    PLOT3D is an interactive graphics program designed to help scientists visualize computational fluid dynamics (CFD) grids and solutions. Today, supercomputers and CFD algorithms can provide scientists with simulations of such highly complex phenomena that obtaining an understanding of the simulations has become a major problem. Tools which help the scientist visualize the simulations can be of tremendous aid. PLOT3D/AMES offers more functions and features, and has been adapted for more types of computers than any other CFD graphics program. Version 3.6b+ is supported for five computers and graphic libraries. Using PLOT3D, CFD physicists can view their computational models from any angle, observing the physics of problems and the quality of solutions. As an aid in designing aircraft, for example, PLOT3D's interactive computer graphics can show vortices, temperature, reverse flow, pressure, and dozens of other characteristics of air flow during flight. As critical areas become obvious, they can easily be studied more closely using a finer grid. PLOT3D is part of a computational fluid dynamics software cycle. First, a program such as 3DGRAPE (ARC-12620) helps the scientist generate computational grids to model an object and its surrounding space. Once the grids have been designed and parameters such as the angle of attack, Mach number, and Reynolds number have been specified, a "flow-solver" program such as INS3D (ARC-11794 or COS-10019) solves the system of equations governing fluid flow, usually on a supercomputer. Grids sometimes have as many as two million points, and the "flow-solver" produces a solution file which contains density, x- y- and z-momentum, and stagnation energy for each grid point. With such a solution file and a grid file containing up to 50 grids as input, PLOT3D can calculate and graphically display any one of 74 functions, including shock waves, surface pressure, velocity vectors, and particle traces. PLOT3D's 74 functions are organized into

  7. Almacenamiento de Trozos de Ñame (Dioscorea rotundata Poir) en Atmósferas Modificadas Modified Atmosphere Packaging of Chunks Yam (Dioscorea rotundata Poir)

    OpenAIRE

    Ricardo D Andrade; Juan C Palacio; Waldir A Pacheco; Robert A Betin

    2012-01-01

    En este trabajo se analizan las condiciones de conservación de trozos de ñame en empaques de películas poliméricas, bajo condiciones de atmósfera modificada. Se determina la tasa de respiración de trozos de ñame a temperatura de refrigeración (5 ± 1°C) y temperatura ambiente (27 ± 1°C) y se evalúan diferentes películas plásticas con atmosfera modificada. La tasa de respiración a temperatura de refrigeración fue de 2.9 ± 0.9 mlCO2/Kg-h (gráficamente) y 3.2 ± 1.0 mlC0(2)/Kg-h (analíticamente), ...

  8. Desarrollo y productividad de ñame (Dioscorea trifida y Dioscorea esculenta en diferentes condiciones hídricas

    Directory of Open Access Journals (Sweden)

    Alba Nelly Acevedo Mercado

    2015-01-01

    Full Text Available En la región Montes de María (9° 24' 56,33" N y 75° 23' 04,19" O, departamento de Sucre, Colombia, en zonas de clima cálido (26 °C y 30 °C y de clima medio (20 °C y 24 °C, humedad relativa entre 75 y 85% y precipitación de 750 mm durante el ensayo se estudió el efecto del riego en el desarrollo y productividad de dos especies de ñame en peligro de extinción (Dioscorea trifida y Dioscorea esculenta en un diseño experimental de parcelas subdivididas, donde las variables fueron tres condiciones hídricas: riego de 888 mm durante la etapa crítica del cultivo, riego de 944 mm durante todo el ciclo del cultivo, y ausencia de riego con una oferta de agua de 750 mm provenientes de precipitación. La densidad de siembra fue de 10,000 plantas/ha, labranza tradicional con arado de discos y cosecha 8 meses después de la siembra. Como variables se midieron rendimiento de ñame, contenido de almidón, longitud y diámetro de tubérculos y biomasa aérea. Dioscorea trifida presentó un rendimiento promedio de 30.6 t/ha y D. esculenta de 27 t/ha, con contenidos de almidón de 21.3 y 21.6% en base húmeda, respectivamente; la longitud promedio de tubérculos para D. trifida fue de 17.4 cm y para D. esculenta de 11.4 cm; los diámetros promedio fueron 14.4 cm y 10.5 cm y la biomasa aérea 1.1 kg/planta y 0.67 kg/planta, respectivamente. La aplicación de riego al cultivo produjo un incremento en la producción con respecto al cultivo sin riego, para Dioscorea trifida este incremento fue de 78.9% y para Dioscorea esculenta de 92.9%.

  9. Forgotten marginalia and the French and Latin manuscript tradition in Le Mirouer des simples ames by Marguerite Porete

    Directory of Open Access Journals (Sweden)

    García Acosta, Pablo

    2014-06-01

    Full Text Available This article advocates a fresh critical study of the manuscripts of the “heretical” book, Le Mirouer des simples ames by Marguerite dicta Porete, and an examination of codicological evidence which neither the standard editions nor the modern translations take into account. It argues for analysis of the codex traditionally known as the Chantilly manuscript (Musée Condé, ms. F xiv 26, cat. 157 and of the manuscripts of the Latin branch preserved in the Vatican Library (Biblioteca Apostolica Vaticana, Vat. Lat. 4355; Cod. Rossianus 4; Cod. Chigianus B IV 41; Cod. Chigianus C IV 85 and Vat. Lat. 4953. The analysis focuses on the marginal marks (maniculae, nota bene and iconography which demonstrate that those books were used by active readers. The article also highlights the way in which the marginal marks provide us with information about the transmission and reception of the Mirror, and classifi es them according to function, depending on whether they facilitate access to, evaluate or even contribute to the meaning of the text of the Mirror itself.En las páginas siguientes reivindicamos un retorno crítico al estudio de los manuscritos del libro “herético” escrito por Marguerite dicta Porete (Le Mirouer des simples ames para estudiar aspectos codicológicos que ni las ediciones estándar ni las traducciones modernas han tenido en cuenta. Para ello, proponemos una serie de análisis del llamado “manuscrito de Chantilly” (Musée Condé, ms. F xiv 26, cat. 157 y de los manuscritos de la tradición latina de la Biblioteca Vaticana (Biblioteca Apostolica Vaticana, Vat. Lat. 4355; Cod. Rossianus 4; Cod. Chigianus B IV 41; Cod. Chigianus C IV 85 y Vat. Lat. 4953 basados en las anotaciones marginales (manículas, nota bene e iconografía que identifican estos libros más como dispositivos de lectura que como meros soportes materiales de un texto. Mostraremos cómo tales elementos nos dotan de información sobre la transmisión del texto y

  10. Applicability domains for classification problems: benchmarking of distance to models for AMES mutagenicity set

    Science.gov (United States)

    For QSAR and QSPR modeling of biological and physicochemical properties, estimating the accuracy of predictions is a critical problem. The “distance to model” (DM) can be defined as a metric that defines the similarity between the training set molecules and the test set compound ...

  11. Prevention of neuromusculoskeletal frailty in slow-aging ames dwarf mice: longitudinal investigation of interaction of longevity genes and caloric restriction.

    Directory of Open Access Journals (Sweden)

    Oge Arum

    Full Text Available Ames dwarf (Prop1 (df/df mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice. Our study objective was to determine whether Ames dwarfism or CR influence neuromusculoskeletal function in middle-aged (82 ± 12 weeks old or old (128 ± 14 w.o. mice. At the examined ages, strength was improved by dwarfism, CR, and dwarfism plus CR in male mice; balance/ motor coordination was improved by CR in old animals and in middle-aged females; and agility/ motor coordination was improved by a combination of dwarfism and CR in both genders of middle-aged mice and in old females. Therefore, extension of longevity by congenital hypopituitarism is associated with improved maintenance of the examined measures of strength, agility, and motor coordination, key elements of frailty during human aging, into advanced age. This study serves as a particularly important example of knowledge related to addressing aging-associated diseases and disorders that results from studies in long-lived mammals.

  12. THE NASA AMES PAH IR SPECTROSCOPIC DATABASE VERSION 2.00: UPDATED CONTENT, WEB SITE, AND ON(OFF)LINE TOOLS

    International Nuclear Information System (INIS)

    A significantly updated version of the NASA Ames PAH IR Spectroscopic Database, the first major revision since its release in 2010, is presented. The current version, version 2.00, contains 700 computational and 75 experimental spectra compared, respectively, with 583 and 60 in the initial release. The spectra span the 2.5-4000 μm (4000-2.5 cm-1) range. New tools are available on the site that allow one to analyze spectra in the database and compare them with imported astronomical spectra as well as a suite of IDL object classes (a collection of programs utilizing IDL's object-oriented programming capabilities) that permit offline analysis called the AmesPAHdbIDLSuite. Most noteworthy among the additions are the extension of the computational spectroscopic database to include a number of significantly larger polycyclic aromatic hydrocarbons (PAHs), the ability to visualize the molecular atomic motions corresponding to each vibrational mode, and a new tool that allows one to perform a non-negative least-squares fit of an imported astronomical spectrum with PAH spectra in the computational database. Finally, a methodology is described in the Appendix, and implemented using the AmesPAHdbIDLSuite, that allows the user to enforce charge balance during the fitting procedure

  13. Large-Scale Wind Turbine Testing in the NASA 24.4m (80) by 36.6m(120) Wind Tunnel

    Science.gov (United States)

    Zell, Peter T.; Imprexia, Cliff (Technical Monitor)

    2000-01-01

    The 80- by 120-Foot Wind Tunnel at NASA Ames Research Center in California provides a unique capability to test large-scale wind turbines under controlled conditions. This special capability is now available for domestic and foreign entities wishing to test large-scale wind turbines. The presentation will focus on facility capabilities to perform wind turbine tests and typical research objectives for this type of testing.

  14. Measurement of isotopic cross sections of the fission fragments produced in 500 AMeV 208Pb + p reaction

    International Nuclear Information System (INIS)

    The aim of this work is the study of the fission fragments produced in the spallation reaction 208Pb + p at 500 AMeV. The fission fragments from Z=23 up to Z=59 have been detected and identified by using the inverse kinematics technique with the high-resolution spectrometer FRS. The production cross sections and the recoil velocities of 430 nuclei have been measured. The measured data have been compared with previous data. The isotopic distributions show a high precision. However, the absolute value of the fission cross section is higher than expected. From the experimental data the characteristics of the average fissioning system have been reconstructed (Zfis, Afis, E*fis). In addition, the number of post-fission neutrons emitted from the fission fragments, vpost, has been determined by using a new method. The experimental data have been compared to the two-steps models describing the spallation reaction. The impact of the model parameters on the observables has been analysed and the reasons Leading to the observed differences between the codes are also presented. This analyse shows a good agreement with the INCL4+ABLA code. (author)

  15. Prevalência de práticas educativas acerca do aleitamento materno exclusivo (AME em Cuiabá - MT

    Directory of Open Access Journals (Sweden)

    Luma Natalia Barbosa

    2015-03-01

    Full Text Available Objetivo: Descrever a prevalência das práticas educativas em saúde sobre o aleitamento materno exclusivo (AME no Município de Cuiabá - MT nos meses de julho a dezembro de 2012. Métodos: Trata-se de um estudo descritivo transversal, realizado junto a mulheres internadas em um hospital. A amostra foi composta por 306 mulheres no período pós-parto imediato. Os dados foram coletados por meio de um questionário semiestruturado. Resultados: Ter oito anos ou mais de estudo (RP = 1,77; ter renda até dois salários mínimos (RP = 1,22; ter planejado a gravidez (RP = 1,31; ter iniciado o atendimento no serviço de pré-natal no primeiro trimestre (RP = 1,65 e serem primíparas (RP = 1,21 são características que aparecem associadas com uma maior chance de receber orientações sobre aleitamento materno do que as demais mulheres. Conclusão: Faz-se necessário repensar mudanças dessas práticas, a fim de se realizar ações educativas que busquem efetivar transformações na relação profissional/usuário, visando o acolhimento das gestantes.

  16. Exploring reaction mechanisms and their competition in 58Ni + 48Ca collisions at E=25 AMeV

    International Nuclear Information System (INIS)

    Latest results concerning the study of central collisions in 58Ni+48Ca reactions at Elab(Ni)=25 AMeV are presented. The experimental data, collected with the CHIMERA 4π device, have been analyzed in order to investigate the competition among different reaction mechanisms for central collisions in the Fermi energy domain. The method adopted to perform the centrality selection refers to the global variable 'flow angle', that is related to the event shape in momentum space, as it is determined by the eigenvectors of the experimental kinetic-energy tensor. The main features of the reaction products were explored by using different constraints on some of the relevant observables, such as mass and velocity distributions and their correlations. Much emphasis was devoted to the competition between fusion-evaporation processes with subsequent identification of a heavy residue and a prompt multifragmentation mechanism. The reaction mechanism was simulated in the framework of transport theories (dynamical stochastic BNV calculations, followed by sequential SIMON code) and further comparison with dynamical calculations from transport model (QMD, CoMD) are in progress. Moreover, an extension of this study taking into account for the light particles has been envisaged. (authors)

  17. Ames Research Center Life Sciences Payload Project for Spacelab Mission 3

    Science.gov (United States)

    Callahan, P. X.; Tremor, J.; Lund, G.; Wagner, W. L.

    1983-01-01

    The Research Animal Holding Facility, developed to support rodent and squirrel monkey animal husbandry in the Spacelab environment, is to be tested during the Spacelab Mission 3 flight. The configuration and function of the payload hardware elements, the assembly and test program, the operational rationale, and the scientific approach of this mission are examined. Topics covered include animal life support systems, the squirrel monkey restraint, the camera-mirror system, the dynamic environment measurement system, the biotelemetry system, and the ground support equipment. Consideration is also given to animal pretests, loading the animals during their 12 hour light cycle, and animal early recovery after landing. This mission will be the first time that relatively large samples of monkeys and rats will be flown in space and also cared for and observed by man.

  18. Evaluation of the Rotational Throttle Interface for Converting Aircraft Utilizing the NASA Ames Vertical Motion Simulator

    Science.gov (United States)

    Rozovski, David; Theodore, Colin R.

    2011-01-01

    An experiment was conducted to compare a conventional helicopter Thrust Control Lever (TCL) to the Rotational Throttle Interface (RTI) for tiltrotor aircraft. The RTI is designed to adjust its orientation to match the angle of the tiltrotor s nacelles. The underlying principle behind the design is to increase pilot awareness of the vehicle s configuration state (i.e. nacelle angle). Four test pilots flew multiple runs on seven different experimental courses. Three predominant effects were discovered in the testing of the RTI: 1. Unintentional binding along the control axis resulted in difficulties with precision power setting, 2. Confusion in which way to move the throttle grip was present during RTI transition modes, and 3. Pilots were not able to distinguish small angle differences during RTI transition. In this experiment the pilots were able to successfully perform all of the required tasks with both inceptors although the handling qualities ratings were slightly worse for the RTI partly due to unforeseen deficiencies in the design. Pilots did however report improved understanding of nacelle movement during transitions with the RTI.

  19. Genotoxicity assessment of the antiepileptic drug AMP397, an Ames-positive aromatic nitro compound.

    Science.gov (United States)

    Suter, Willi; Hartmann, Andreas; Poetter, Franziska; Sagelsdorff, Peter; Hoffmann, Peter; Martus, Hans-Jörg

    2002-07-25

    AMP397 is a novel antiepileptic agent and the first competitive AMPA antagonist with high receptor affinity, good in vivo potency, and oral activity. AMP397 has a structural alert (aromatic nitro group) and was mutagenic in Salmonella typhimurium strains TA97a, TA98 and TA100 without S9, but negative in the nitroreductase-deficient strains TA98NR and TA100NR. The amino derivative of AMP397 was negative in wild-type strains TA98 and TA100. AMP397 was negative in a mouse lymphoma tk assay, which included a 24h treatment without S9. A weak micronucleus induction in vitro was found at the highest concentrations tested in V79 cells with S9. AMP397 was negative in the following in vivo studies, which included the maximum tolerated doses of 320mg/kg in mice and 2000mg/kg in rats: MutaMouse assay in colon and liver (5x320mg/kg) at three sampling times (3, 7 and 31 days after the last administration); DNA binding study in the liver of mice and rats after a single treatment with [14C]-AMP397; comet assay (1x2000mg/kg) in jejunum and liver of rats, sampling times 3 and 24h after administration; micronucleus test (2x320mg/kg) in the bone marrow of mice, sampling 24h after the second administration. Based on these results, it was concluded that AMP397 has no genotoxic potential in vivo. In particular, no genotoxic metabolite is formed in mammalian cells, and, if formed by intestinal bacteria, is unable to exert any genotoxic activity in the adjacent intestinal tissue. These data were considered to provide sufficient safety to initiate clinical development of the compound. PMID:12113769

  20. 2011 Ground Testing Highlights Article

    Science.gov (United States)

    Ross, James C.; Buchholz, Steven J.

    2011-01-01

    Two tests supporting development of the launch abort system for the Orion MultiPurpose Crew Vehicle were run in the NASA Ames Unitary Plan wind tunnel last year. The first test used a fully metric model to examine the stability and controllability of the Launch Abort Vehicle during potential abort scenarios for Mach numbers ranging from 0.3 to 2.5. The aerodynamic effects of the Abort Motor and Attitude Control Motor plumes were simulated using high-pressure air flowing through independent paths. The aerodynamic effects of the proximity to the launch vehicle during the early moments of an abort were simulated with a remotely actuated Service Module that allowed the position relative to the Crew Module to be varied appropriately. The second test simulated the acoustic environment around the Launch Abort Vehicle caused by the plumes from the 400,000-pound thrust, solid-fueled Abort Motor. To obtain the proper acoustic characteristics of the hot rocket plumes for the flight vehicle, heated Helium was used. A custom Helium supply system was developed for the test consisting of 2 jumbo high-pressure Helium trailers, a twelve-tube accumulator, and a 13MW gas-fired heater borrowed from the Propulsion Simulation Laboratory at NASA Glenn Research Center. The test provided fluctuating surface pressure measurements at over 200 points on the vehicle surface that have now been used to define the ground-testing requirements for the Orion Launch Abort Vehicle.

  1. Decay of excited nuclei produced in 78,82Kr+40Ca reactions at 5.5 AMeV

    International Nuclear Information System (INIS)

    In this work we study the decay modes of excited nuclei formed in 78,82Kr+40Ca reactions at 5.5 AMeV. The 4π INDRA array was used to measure light charged particles, evaporation residues and fragments with atomic number 3≤Z≤28. In both reactions, fragment characteristics are compatible with a fission like phenomenon. Persistence of structure effects is evidenced from a strong odd-even staggering of the light-fragment (6≤Z≤11) yields. The magnitude of the staggering does not significantly depend on the neutron content of the system. Light particle-fragment coincidences suggest that those fragments are excited below the particle emission thresholds. For the neutron-poor system, the evaporation residue cross-section is slightly higher and the fission-like component is larger by ∼ 25%. These features were confronted to the predictions of statistical and dynamical models. For both reactions, the transition-state formalism reasonably reproduces the Z-distribution around the symmetry but strongly overestimates the light-fragment cross-sections and failed to explain the staggering of their yields. The Z-distribution shape and the staggering of the light-fragment yields are satisfactorily reproduced within the dinuclear system framework which associates the heavy fragments to quasi-fission while light fragments are predominantly populated by fusion. However, none of the models are able to reproduce the characteristics of the kinetic energy spectra. This would indicate the need to improve the description of large deformation experienced by the system at the separation phase. (author)

  2. Antimutagenic activity of major fractions of Zataria multiflora Boiss by Ames method

    Directory of Open Access Journals (Sweden)

    Fariba Sharififar

    2015-01-01

    Full Text Available Zataria multiflora is a medicinal plant that has been interested in antimutagenicity effect because of its high antioxidant activity and richness of flavonoids. Antimutagenicity effect of total extract of the plant has been reported previously. Aerial parts of Z. multiflora were extracted by petroleum ether, chloroform and 80% methanol by liquid-liquid extraction method consequently. The fractions were concentrated in vacuum and dried at 40°C in oven. The genotype of two standard strains of Salmonella typhimurium (TA98, TA100 was confirmed by the evaluation of two important factors of histidine requirement and the presence of R factor. The minimum inhibition concentration (MIC of the fractions against these two strains was determined by agar dilution method. From each fraction, various concentrations less than MIC were studied for anti-mutagenic test. The sample along with bacterial strain and mutagen agent were incubated at 37°C for 48 h. The number of revertant colonies was counted and compared with control plates. Our results showed that all fractions especially petroleum ether and chloroform ones maintain the number of colonies in the standard range in control plates and prevent from the growth of many strains of bacteria and increase of revertant colonies enhancement in a concentration-dependent manner. This effect was prominent against TA100 starin. Methanolic fraction exhibited anti-mutagen activity just in the highest used concentration in the presence of TA98.

  3. The use of an automated flight test management system in the development of a rapid-prototyping flight research facility

    Science.gov (United States)

    Duke, Eugene L.; Hewett, Marle D.; Brumbaugh, Randal W.; Tartt, David M.; Antoniewicz, Robert F.; Agarwal, Arvind K.

    1988-01-01

    An automated flight test management system (ATMS) and its use to develop a rapid-prototyping flight research facility for artificial intelligence (AI) based flight systems concepts are described. The ATMS provides a flight test engineer with a set of tools that assist in flight planning and simulation. This system will be capable of controlling an aircraft during the flight test by performing closed-loop guidance functions, range management, and maneuver-quality monitoring. The rapid-prototyping flight research facility is being developed at the Dryden Flight Research Facility of the NASA Ames Research Center (Ames-Dryden) to provide early flight assessment of emerging AI technology. The facility is being developed as one element of the aircraft automation program which focuses on the qualification and validation of embedded real-time AI-based systems.

  4. Heavy Residues with A<90 in the Asymmetric Reaction of 20 AMeV 124Sn+27Al as a Sensitive Probe of the Onset of Multifragmentation

    OpenAIRE

    Veselsky, M; Souliotis, G. A.; Chubarian, G.; Trache, L.; Keksis, A.; martin, E.; Ruangma, A.; Winchester, E; Yennello, S. J.

    2002-01-01

    The cross sections and velocity distributions of heavy residues from the reaction of 20 AMeV 124Sn + 27Al have been measured at forward angles using the MARS recoil separator at Texas A&M in a wide mass range. A consistent overall description of the measured cross sections and velocity distributions was achieved using a model calculation employing the concept of deep-inelastic transfer for the primary stage of peripheral collisions, pre-equilibrium emission and incomplete fusion for the prima...

  5. Evaluación del almidón de ñame espino (dioscorearotundata) como estabilizante en la elaboración de yogur entero tipo batido

    OpenAIRE

    R. Mendoza Navarro; Y. TRUJILLO NAVARRO; D. Duran Osorio

    2007-01-01

    El proceso de elaboración de yogur es una compleja combinación de ciencia y arte,donde el principal objetivo de las industrias lácteas ha sido mejorar y/o mantener sucalidad. Para tal fin, se evaluó el almidón de ñame espino (Dioscorea rotundata) comoestabilizante en la elaboración de yogur entero tipo batido, con el propósito de dar nuevasalternativas de uso agroalimentario. Para lo cual, se prepararon muestras de yogur cony sin estabilizante (ITAL 1000Y) a la concentración de 0,3% (p/v) y ...

  6. Study of the heavy ions (Au+Au at 150 AMeV) collisions with the FOPI detector. Comparison with the Landau-Vlasov model

    International Nuclear Information System (INIS)

    In this thesis, heavy ions (Au+Au) collisions experiments are made at 150 AMeV.In the first part, a general study of the nuclear matter equation is presented. Then the used Landau-Vlasov theoretical model is describe. The third part presents the FOPI experience and the details of how to obtain this theoretical predictions (filter, cuts, corrections, possible centrality selections).At the end, experimental results and comparisons with the Landau-Vlasov model are presented. (TEC). 105 refs., 96 figs., 14 tabs

  7. A New Way of Doing Business: Reusable Launch Vehicle Advanced Thermal Protection Systems Technology Development: NASA Ames and Rockwell International Partnership

    Science.gov (United States)

    Carroll, Carol W.; Fleming, Mary; Hogenson, Pete; Green, Michael J.; Rasky, Daniel J. (Technical Monitor)

    1995-01-01

    NASA Ames Research Center and Rockwell International are partners in a Cooperative Agreement (CA) for the development of Thermal Protection Systems (TPS) for the Reusable Launch Vehicle (RLV) Technology Program. This Cooperative Agreement is a 30 month effort focused on transferring NASA innovations to Rockwell and working as partners to advance the state-of-the-art in several TPS areas. The use of a Cooperative Agreement is a new way of doing business for NASA and Industry which eliminates the traditional customer/contractor relationship and replaces it with a NASA/Industry partnership.

  8. Multiplicación y tuberización in vitro de ñame (dioscorea alata l.) en sistema de inmersión temporal.

    OpenAIRE

    Salazar Díaz, Robinson; Hoyos Sánchez, Rodrigo Alberto

    2011-01-01

    Se realizó la estandarización de la multiplicación y tuberización in vitro de ñame (Dioscorea alata L.) utilizando el sistema de inmersión temporal conocido como RITA®. Se evaluó inicialmente el porcentaje de brotación de segmentos nodales en medio de cultivo semisólido utilizando dos tipos de citoquininas (BAP y Kinetina). Las plantas obtenidas fueron subcultivadas cada cuatro semanas y luego utilizadas para la obtención de meristemos y plántulas para llevar a cabo los diferentes experimento...

  9. Evaluación de métodos para la conservación de hongos fitopatógenos del ñame (dioscorea sp).

    OpenAIRE

    Yeimy Alexandra Pinzón Gutiérrez

    2009-01-01

    Un elemento esencial en la investigación con microorganismos fitopatógenos es su conservación y uso seguro. Desde este punto de vista, en este estudio se evaluaron métodos de conservación de hongos que atacan el ñame, empleando como factores de respuesta el potencial de viabilidad, y la estabilidad y presencia o ausencia de cambios en las características macro y microscópicas. Como resultado del trabajo se proponen los métodos más adecuados para los géneros Colletotrichum y Fusarium, hongos c...

  10. Reflections About the Role of Intellectuals in Latin America Reflexiones acerca del rol de los intelectuales en América Latina Reflexões sobre o papel dos intelectuais na América Latina

    Directory of Open Access Journals (Sweden)

    Judith Naidorf

    2010-10-01

    intellectual debate but to contribute to a not new but always applicable, which should be a breakthrough for each of our practices in the different social areas in which we daily work.

    En este trabajo nos proponemos abordar algunos aspectos teórico - conceptuales que contribuyan a la reflexión sobre la especificidad del papel del intelectual latinoamericano actual. Los aportes de diversos autores nos ayudarán a caracterizar un rol que se encuentra en permanente reformulación, análisis y discusión. La propuesta es retomar los desarrollos teóricos de la categoría de intelectual, desde Antonio Gramsci e Immanuel Wallerstein principalmente, pasando por sus momentos más intensos en la década del 60-70 con Sartre y Foucault en Europa. También se rescatan las contribuciones realizadas por Pierre Bourdieu, Sousa Santos y los aportes para América Latina de Fals Borda, Florestán Fernández, Octavio Ianni y Eliseo Verón, entre otros. Además se incluyen como ejemplos declaraciones del subcomandante Marcos para el EZLN y se hace referencia a los análisis realizados por Julio Gambina y Daniel Campione para el caso argentino. No es interés de este trabajo arribar a definiciones acabadas acerca de la función social del intelectual sino aportar a un debate no nuevo pero siempre vigente. Neste trabalho pretendemos abordar alguns aspectos teóricos-conceituais que contribuem para a reflexão sobre especificidade do papel do intelectual latino-americano atual. As contribuições de diferentes autores nos ajudam a caracterizar um papel que está constantemente sendo repensado, a análisado e discutido. A proposta é revisitar aos desenvolvimentos teóricos sobre o "intelectual" de Antonio Gramsci e Emanuel Wallerstein principalmente através dos debates mais intensos na década de 60-70 com Sartre e Foucault na Europa. Também se destacam as contribuições feitas por Pierre Bourdieu, Sousa Santos e contribuições desde América Latina de

  11. New results from the analyses of the solid phase of the NASA Ames Titan Haze Simulation (THS) experiment

    Science.gov (United States)

    Sciamma-O'Brien, Ella; Upton, Kathleen T.; Beauchamp, Jesse L.; Salama, Farid

    2015-11-01

    In Titan’s atmosphere, a complex chemistry occurs at low temperature between N2 and CH4 that leads to the production of heavy organic molecules and subsequently solid aerosols. The Titan Haze Simulation (THS) experiment was developed at the NASA Ames COSmIC facility to study Titan’s atmospheric chemistry at low temperature. In the THS, the chemistry is simulated by plasma in the stream of a supersonic expansion. With this unique design, the gas is cooled to Titan-like temperature (~150K) before inducing the chemistry by plasma, and remains at low temperature in the plasma (~200K). Different N2-CH4-based gas mixtures can be injected in the plasma, with or without the addition of heavier molecules, in order to monitor the evolution of the chemical growth.Following a recent in situ mass spectrometry study of the gas phase that demonstrated that the THS is a unique tool to probe the first and intermediate steps of Titan’s atmospheric chemistry at low temperature (Sciamma-O’Brien et al., Icarus, 243, 325 (2014)), we have performed a complementary study of the solid phase. The findings are consistent with the chemical growth evolution observed in the gas phase. Grains and aggregates form in the gas phase and can be jet deposited onto various substrates for ex situ analyses. Scanning Electron Microscopy images show that more complex mixtures produce larger aggregates, and that different growth mechanisms seem to occur depending on the gas mixture. They also allow the determination of the size distribution of the THS solid grains. A Direct Analysis in Real Time mass spectrometry analysis coupled with Collision Induced Dissociation has detected the presence of aminoacetonitrile, a precursor of glycine, in the THS aerosols. X-ray Absorption Near Edge Structure (XANES) measurements also show the presence of imine and nitrile functional groups, showing evidence of nitrogen chemistry. Infrared and µIR spectra of samples deposited on KBr and Si substrates show the

  12. An Overview of Current Capabilities and Research Activities in the Airspace Operations Laboratory at NASA Ames Research Center

    Science.gov (United States)

    Prevot, Thomas; Smith, Nancy M.; Palmer, Everett; Callantine, Todd; Lee, Paul; Mercer, Joey; Homola, Jeff; Martin, Lynne; Brasil, Connie; Cabrall, Christopher

    2014-01-01

    The Airspace Operations Laboratory at NASA Ames conducts research to provide a better understanding of roles, responsibilities, and requirements for human operators and automation in future air traffic management (ATM) systems. The research encompasses developing, evaluating, and integrating operational concepts and technologies for near-, mid-, and far-term air traffic operations. Current research threads include efficient arrival operations, function allocation in separation assurance and efficient airspace and trajectory management. The AOL has developed powerful air traffic simulation capabilities, most notably the Multi Aircraft Control System (MACS) that is used for many air traffic control simulations at NASA and its partners in government, academia and industry. Several additional NASA technologies have been integrated with the AOL's primary simulation capabilities where appropriate. Using this environment, large and small-scale system-level evaluations can be conducted to help make near-term improvements and transition NASA technologies to the FAA, such as the technologies developed under NASA's Air Traffic Management Demonstration-1 (ATD-1). The AOL's rapid prototyping and flexible simulation capabilities have proven a highly effective environment to progress the initiation of trajectory-based operations and support the mid-term implementation of NextGen. Fundamental questions about accuracy requirements have been investigated as well as realworld problems on how to improve operations in some of the most complex airspaces in the US. This includes using advanced trajectory-based operations and prototype tools for coordinating arrivals to converging runways at Newark airport and coordinating departures and arrivals in the San Francisco and the New York metro areas. Looking beyond NextGen, the AOL has started exploring hybrid human/automation control strategies as well as highly autonomous operations in the air traffic control domain. Initial results

  13. EVALUACIÓN DE LAS PROPIEDADES MODIFICADAS POR VÍA ENZIMÁTICA DEL ALMIDÓN DE ÑAME (D. trífida) UTILIZANDO α-AMILASA (TERMAMYL® 120 L, TIPO L)

    OpenAIRE

    Everaldo Montes M; Jairo Salcedo M; José E Zapata M; Jesús Carmona C; Sergio Paternina U

    2008-01-01

    El almidón de ñame constituye una excelente materia prima para modificar la textura y consistencia de los alimentos. Su funcionalidad depende del peso molecular promedio de la amilosa y la amilopectina, así como de la organización molecular de estos glucanos dentro del gránulo. Con frecuencia los almidones nativos o naturales no son los más adecuados para uso en algunos procesos industriales específicos. Este trabajo tiene como objetivo la modificación por vía enzimática del almidón de ñame (...

  14. NASA Ames DEVELOP Interns Collaborate with the South Bay Salt Pond Restoration Project to Monitor and Study Restoration Efforts using NASA's Satellites

    Science.gov (United States)

    Newcomer, Michelle E.; Kuss, Amber Jean; Nguyen, Andrew; Schmidt, Cynthia L.

    2012-01-01

    In the past, natural tidal marshes in the south bay were segmented by levees and converted into ponds for use in salt production. In an effort to provide habitat for migratory birds and other native plants and animals, as well as to rebuild natural capital, the South Bay Salt Pond Restoration Project (SBSPRP) is focused on restoring a portion of the over 15,000 acres of wetlands in California's South San Francisco Bay. The process of restoration begins when a levee is breached; the bay water and sediment flow into the ponds and eventually restore natural tidal marshes. Since the spring of 2010 the NASA Ames Research Center (ARC) DEVELOP student internship program has collaborated with the South Bay Salt Pond Restoration Project (SBSPRP) to study the effects of these restoration efforts and to provide valuable information to assist in habitat management and ecological forecasting. All of the studies were based on remote sensing techniques -- NASA's area of expertise in the field of Earth Science, and used various analytical techniques such as predictive modeling, flora and fauna classification, and spectral detection, to name a few. Each study was conducted by a team of aspiring scientists as a part of the DEVELOP program at Ames.

  15. Application of satellite data to the studies of agricultural meteorology: Relationship between ground temperature from GMS IR data and AMeDAS air temperature

    International Nuclear Information System (INIS)

    The purpose of the present study is to estimate air temperature in areas where there is no meteorological observation site, using satellite thermal IR data. Surface temperature from GMS IR data derived by eq. (1) was compared with AMeDAS (meteorological observation site) air temperature. The results are summarized as follows: 1) The maximum correlation coefficients between AMeDAS air temperature and surface temperature from GMS IR data is 0.90, the minimum is 0.30 and the mean is 0.60±0.15. 2) The correlation coefficients are affected by the precipitable water and decrease with increasing precipitable Water as shown in Fig. 2. 3) The correlation coefficients for each GMS observed time are better at night and in the morning than during the day (Table 2). 4) Also, the small values of the regression coefficients appear during the day and the large values at night and in the morning (Table 2). 5) The standard deviations which indicated scattering around the regression line are large at 12:00 and 15:00, but small at 06:00 and 09:00 (Table 2). The reason that correlation coefficients, regression coefficients and standard deviations between AMeDAS air temperature and surface temperature from GMS IR data are less during the day than at night and in the morning, is caused by ground conditions because the effects of solar radiation on surface temperature depend on ground surface conditions: plant cover, incline of slope etc. The hourly mean deviation from the regression line for surface temperature was calculated to investigate the characteristic of ground surface conditions for each AMeDAS observation site. AMeDAS observation sites were classified into four types according to the patterns of the hourly mean deviation as shown in Fig. 5. Most of type I were distributed in the plain regions: Ishikari, Konsen and Tokachi. Type II appears in the basin regions and type III on the coast of the Pacific Ocean and the Sea of Okhotsuk. The remaining areas are type IV. The standard

  16. Flight tests of IFR landing approach systems for helicopters

    Science.gov (United States)

    Bull, J. S.; Hegarty, D. M.; Peach, L. L.; Phillips, J. D.; Anderson, D. J.; Dugan, D. C.; Ross, V. L.

    1981-01-01

    Joint NASA/FAA helicopter flight tests were conducted to investigate airborne radar approaches (ARA) and microwave landing system (MLS) approaches. Flight-test results were utilized to prove NASA with a data base to be used as a performance measure for advanced guidance and navigation concepts, and to provide FAA with data for establishment of TERPS criteria. The first flight-test investigation consisted of helicopter IFR approaches to offshore oil rigs in the Gulf of Mexico, using weather/mapping radar, operational pilots, and a Bell 212 helicopter. The second flight-test investigation consisted of IFR MLS approaches at Crows Landing (near Ames Research Center), with a Bell UH-1H helicopter, using NASA, FAA, and operational industry pilots. Tests are described and results discussed.

  17. Report of the Interagency Optical Network Testbeds Workshop 2 September 12-14, 2006 NASA Ames Research Center

    Energy Technology Data Exchange (ETDEWEB)

    Joe Mambretti Richard desJardins

    2006-05-01

    A new generation of optical networking services and technologies is rapidly changing the world of communications. National and international networks are implementing optical services to supplement traditional packet routed services. On September 12-14, 2005, the Optical Network Testbeds Workshop 2 (ONT2), an invitation-only forum hosted by the NASA Research and Engineering Network (NREN) and co-sponsored by the Department of Energy (DOE), was held at NASA Ames Research Center in Mountain View, California. The aim of ONT2 was to help the Federal Large Scale Networking Coordination Group (LSN) and its Joint Engineering Team (JET) to coordinate testbed and network roadmaps describing agency and partner organization views and activities for moving toward next generation communication services based on leading edge optical networks in the 3-5 year time frame. ONT2 was conceived and organized as a sequel to the first Optical Network Testbeds Workshop (ONT1, August 2004, www.nren.nasa.gov/workshop7). ONT1 resulted in a series of recommendations to LSN. ONT2 was designed to move beyond recommendations to agree on a series of “actionable objectives” that would proactively help federal and partner optical network testbeds and advanced research and education (R&E) networks to begin incorporating technologies and services representing the next generation of advanced optical networks in the next 1-3 years. Participants in ONT2 included representatives from innovative prototype networks (Panel A), basic optical network research testbeds (Panel B), and production R&D networks (Panels C and D), including “JETnets,” selected regional optical networks (RONs), international R&D networks, commercial network technology and service providers (Panel F), and senior engineering and R&D managers from LSN agencies and partner organizations. The overall goal of ONT2 was to identify and coordinate short and medium term activities and milestones for researching, developing, identifying

  18. Testing the Product Test

    OpenAIRE

    Brea, H.; Grifell-Tatjé, Emili; Lovell, C.A. Knox

    2010-01-01

    The product test asks the product of a quantity index number and a price index number to equal the corresponding value change. The literature treats the product test as being so important that it is used to identify acceptable index number pairs, and to construct implicit index numbers when an otherwise desirable pair fails the test. We treat the product test as a hypothesis to be tested, and we provide an empirical application.

  19. Dynamic response of NASA Rotor Test Apparatus and Sikorsky S-76 hub mounted in the 80- by 120-Foot Wind Tunnel

    Science.gov (United States)

    Peterson, Randall L.; Hoque, Muhammed S.

    1994-01-01

    A shake test was conducted in the 80- by 120-Foot Wind Tunnel at NASA Ames Research Center, using the NASA Ames Rotor Test Apparatus (RTA) and the Sikorsky S-76 rotor hub. The primary objective of this shake test was to determine the modal properties of the RTA, the S-76 rotor hub, and the model support system installed in the wind tunnel. Random excitation was applied at the rotor hub, and vibration responses were measured using accelerometers mounted at various critical locations on the model and the model support system. Transfer functions were computed using the load cell data and the accelerometer responses. The transfer function data were used to compute the system modal parameters with the aid of modal analysis software.

  20. Cyclic Crack Growth Testing of an A.O. Smith Multilayer Pressure Vessel with Modal Acoustic Emission Monitoring and Data Assessment

    Science.gov (United States)

    Ziola, Steven M.

    2014-01-01

    Digital Wave Corp. (DWC) was retained by Jacobs ATOM at NASA Ames Research Center to perform cyclic pressure crack growth sensitivity testing on a multilayer pressure vessel instrumented with DWC's Modal Acoustic Emission (MAE) system, with captured wave analysis to be performed using DWCs WaveExplorerTM software, which has been used at Ames since 2001. The objectives were to document the ability to detect and characterize a known growing crack in such a vessel using only MAE, to establish the sensitivity of the equipment vs. crack size and / or relevance in a realistic field environment, and to obtain fracture toughness materials properties in follow up testing to enable accurate crack growth analysis. This report contains the results of the testing.

  1. Safety Evaluation of Multiple Strains of Lactobacillus plantarum and Pediococcus pentosaceus in Wistar Rats Based on the Ames Test and a 28-Day Feeding Study

    Directory of Open Access Journals (Sweden)

    Cheng-Chih Tsai

    2014-01-01

    Full Text Available Three lactic acid bacterial strains, Lactobacillus plantarum, HK006, and HK109, and Pediococcus pentosaceus PP31 exhibit probiotic potential as antiallergy agents, both in vitro and in vivo. However, the safety of these new strains requires evaluation when isolated from infant faeces or pickled cabbage. Multiple strains (HK006, HK109, and PP31 were subject to a bacterial reverse mutation assay and a short-term oral toxicity study. The powder product exhibited mutagenic potential in Salmonella Typhimurium strains TA98 and TA1535 (with or without metabolic activation. In the short-term oral toxicity study, rats received a normal dosage of 390 mg/kg/d (approximately 9×109 CFU/kg/d or a high dosage of 1950 mg/kg/d (approximately 4.5×1010 CFU/kg/d for 28 d. No adverse effects were observed regarding the general condition, behaviour, growth, feed and water consumption, haematology, clinical chemistry indices, organ weights, or histopathologic analysis of the rats. These studies have demonstrated that the consumption of multiple bacterial strains is not associated with any signs of mutagenicity of S. Typhimurium or toxicity in Wistar rats, even after consuming large quantities of bacteria.

  2. Genotoxicity assays of shellfish by Ames test%Ames试验对海产贝类遗传毒性的检测

    Institute of Scientific and Technical Information of China (English)

    刘材材; 项凌云; 王金辉; 张昊飞; 叶属峰; 徐韧; 程祥圣

    2010-01-01

    采用Ames试验结合小白鼠生物学试验对贝类腹泻性贝毒(diarrhetic shellfish poisoning,DSP)的提取物进行了遗传毒性初步研究.结果表明:4份贝类样品不同程度地受到了遗传毒物的污染,7份贝类样品受到腹泻性贝毒污染.同时本文也从实践上证明在我国海洋环境监测开展Ames试验对贝类遗传毒性检测具有极为重要的意义.

  3. Almacenamiento de Trozos de Ñame (Dioscorea rotundata Poir en Atmósferas Modificadas Modified Atmosphere Packaging of Chunks Yam (Dioscorea rotundata Poir

    Directory of Open Access Journals (Sweden)

    Ricardo D Andrade

    2012-01-01

    Full Text Available En este trabajo se analizan las condiciones de conservación de trozos de ñame en empaques de películas poliméricas, bajo condiciones de atmósfera modificada. Se determina la tasa de respiración de trozos de ñame a temperatura de refrigeración (5 ± 1°C y temperatura ambiente (27 ± 1°C y se evalúan diferentes películas plásticas con atmosfera modificada. La tasa de respiración a temperatura de refrigeración fue de 2.9 ± 0.9 mlCO2/Kg-h (gráficamente y 3.2 ± 1.0 mlC0(2/Kg-h (analíticamente, y a temperatura ambiente de 20.1 ± 0.8 mlCO2/Kg-h (gráficamente y 22.4 ± 0.9 mlC0(2/Kg-h (analíticamente. El empacado en atmósfera modificada de los trozos de ñame mínimamente procesado, no resulta una buena alternativa, debido a que las condiciones de calidad del producto se ven afectadas, presentando un tiempo de vida útil corto entre 6-10 días.In this work storage conditions of chunks yam packed in polymer films with modified atmosphere are analyzed. Respiration rate of chunks yam at refrigeration temperature (5 ± 1°C and room temperature (27 ± 1°C and different films with modified atmosphere were evaluated. Respiration rate at refrigeration temperature was 2.9 ± 0.9 mlC0(2/Kg-h (graphically and 3.2 ± 1.0 mlC0(2/Kg-h (analytically, and room temperature of 20.1 ± 0.8 mlCO2/Kg-h (graphically and 22.4 ± 0.9 mlC0(2/Kg-h (analytically. Modified atmosphere packaging of minimally processed chunks yam is not a good alternative. This because the product quality is affected, with shelf life between 6 and10 days.

  4. Elastic and inelastic scattering of 9,11 Li + Si at backward angles in the energy range (9.5 - 25) AMeV

    International Nuclear Information System (INIS)

    Recently, an inclusive fusion experiment of 9,11 Li projectiles with Si targets, in the energy range (9.5 - 25) AMeV has been performed at Riken Ring Cyclotron-Japan using, for the detection of the fusion products, an ionization chamber, MUSIC, built in NIPNE-HH, Bucharest. In this experiment, the contribution of elastic and inelastic scattering, at forward detection angles is eliminated through the experimental set-up. For a clear investigation of the fusion process, the estimation of elastic and inelastic scattering at backward angles, between 80 angle - 180 angle was considered necessary. This estimation was made by the coupled channels computer code ECIS. ECIS is an iterative method, the first iteration of this procedure being DWBA. In the analysis of elastic and inelastic scattering of 9,11 Li projectile on Si target we assumed that the incident 9 Li and 11 Li waves are diffracted by an optical potential with an Woods-Saxon geometry. The adopted optical potential is given. For the depth of the real and imaginary volume terms we used values dependent on projectile energy and target mass number. These values have been chosen in good agreement with a semi-microscopic model with a double-folding potential. The set of optical parameters selected for the system 9,11 Li (13 AMeV) + Si is given. The presence of neutron halo of 11 Li nucleus was taken into account by using adjusted values for the parameters rR and aR. The 28 Si nucleus is considered a rigid rotor, including the couplings involving the ground state and a first to excited states. The quadrupole deformation parameter was β2 = - 0.24. The results for the scattering of 11 Li projectile on Si target at 13 AMeV energy are given with the parameters Rmatch, I and Jmax taken from the Monte Carlo simulations with PACE code. We found that the contribution of elastic and inelastic scattering for background angles, between 80 angle - 180 angle is under 2%. The contribution of a inelastic scattering taken into

  5. Chlamydia Testing

    Science.gov (United States)

    ... Amplification Test (NAAT); Chlamydia trachomatis Culture; Chlamydia trachomatis DNA Probe Related tests: Gonorrhea Testing , HIV Antibody and HIV Antigen , Syphilis Tests , Herpes Testing , HPV Test , Trichomonas Testing All content on Lab Tests Online has ...

  6. Syphilis Test

    Science.gov (United States)

    ... Gonorrhea Testing , Chlamydia Testing , Herpes Testing , HPV Test , Trichomonas Testing , CSF Analysis All content on Lab Tests ... testing ( polymerase chain reaction, PCR )--this test detects genetic material from the bacteria in the sample from ...

  7. SSI-ARC Flight Test 3 Data Review

    Science.gov (United States)

    Gong, Chester; Wu, Minghong G.

    2015-01-01

    The "Unmanned Aircraft System (UAS) Integration into the National Airspace System (NAS)" Project conducted flight test program, referred to as Flight Test 3, at Armstrong Flight Research Center from June - August 2015. Four flight test days were dedicated to the NASA Ames-developed Detect and Avoid (DAA) System referred to as Autoresolver. The encounter scenarios, which involved NASA's Ikhana UAS and a manned intruder aircraft, were designed to collect data on DAA system performance in real-world conditions and uncertainties with four different surveillance sensor systems. Resulting flight test data and analysis results will be used to evaluate the DAA system performance (e.g., trajectory prediction accuracy, threat detection) and to add fidelity to simulation models used to inform Minimum Operating Performance Standards (MOPS) for integrating UAS into routine NAS operations.

  8. ISODEC Experiment: study and comparison of the decay mode of 78Kr+40Ca and 86Kr+48Ca systems at 10 AMeV

    International Nuclear Information System (INIS)

    We present the first results of the ISODEC experiment, performed at the INFN-LNS with the CHIMERA device, in order to study the competition between the various disintegration modes of 118,134Ba compound nuclei produced by bombarding 40,48Ca targets with beams of 78,86Kr at 10 AMeV. This work aims thus to explore the isospin dependence of the decay modes of medium mass compound nuclei formed by fusion processes. The experiment complements data already obtained at 5.5 MeV/A for 78,82Kr+40Ca reactions, studied by Ademard et al. with beams delivered by GANIL facility and by using the INDRA detector. (authors)

  9. Study of two- and multi-particle correlations in 12C+24Mg and 12C+208Pb reactions at E=35 AMeV

    Directory of Open Access Journals (Sweden)

    Quattrocchi L.

    2016-01-01

    Full Text Available Two and multi particle correlations from the decay of sources produced in 12C+24Mg and 12C+208Pb collisions at E=35 AMeV have been studied by using the forward part (1° < θlab < 30° of the CHIMERA multi-detector. Correlations and invariant mass spectroscopy are used to explore simultaneous and sequential decays of resonances in light isotopes with Z∼3-6, produced in peripheral collisions via the break-up of excited quasi-projectiles. Among them we mention 5Li, 6Li, 6Be, 8Be and the astrophysically important state in 12C decaying into three alpha particles. Results and future perspectives at the INFN-LNS will be presented.

  10. A Tale of Two Small Business Grants: The Best of Times, the Worst of Times from the NASA Ames Small Business Innovative Research (SBIR) Program

    Science.gov (United States)

    Kojiro, Daniel R.; Lee, Geoffrey S.

    2006-01-01

    The purposes of the SBIR Program are to: stimulate technological innovation in the private sector; strengthen the role of Small Business Concerns (SBCs) in meeting Federal research and development needs; increase the commercial application of these research results; and encourage participation of socially and economically disadvantaged persons and women-owned small businesses. The process can be highly rewarding, providing the small business with resources to pursue research and development with a focus on providing NASA with new and advanced capabilities. We present two examples of how the NASA Ames SBIR Program has addressed these purposes, nurturing innovative ideas from small, businesses into commercially viable products that also address analytical needs in space research. These examples, from the Science Instruments for Conducting Solar System Exploration Subtopic, describe the journey from innovative concept to analytical instrument, one successful and one hampered by numerous roadblocks (including some international intrigue}.

  11. Die aktive Beteiligung deutschsprachiger Länder an den Konferenzen der Association for Medical Education in Europe (AMEE zwischen 2005 und 2013: Spiegelbild der Entwicklung der medizinischen Ausbildungsforschung?

    Directory of Open Access Journals (Sweden)

    Raes, Patricia

    2014-08-01

    Full Text Available [english] Objectives: Medical education is gaining in significance internationally. A growing interest in the field has been observed in German-speaking countries (Austria, Germany, Switzerland since the early 2000s. This interest is not, however, reflected in an increase in the number of publications on medical education of German-speaking authors in international professional journals. The following investigation examines the potential use of active participant numbers of German-speaking researchers at AMEE conferences as a means of measuring said development. Methods: The AMEE conference proceedings from the categories and from the years 2005-2013 were examined for evidence of Austrian, German and Swiss participation. The abstracts were subsequently analysed in terms of content and categorised according to , and .Results: Of the 9,446 analysed abstracts, 549 contributions show at least one first, last or co-author from Austria, Germany or Switzerland. The absolute number of contributions per conference varied between 44 in 2010 and 77 in 2013. The percentage fluctuated between 10% in 2005 and 4.1% in 2010. From the year 2010 onwards, however, participation increased continually. The research was predominantly descriptive (62.7%. Studies on fundamental questions of teaching and learning ( were less frequent (4.0%. For the most part, quantitative methods (51.9% were implemented in addressing subjects such as (33%, (22.4% or (14.4%. The study population was usually comprised of students (52.5%.Conclusions: The number of contributions from Austria, Germany and Switzerland peak at the beginning and at the end of the evaluated period of time. A continual increase in active participation since 2005 was not observed. These observations do not reflect the actual increase of interest in medical education research in German-speaking countries.

  12. Human Monoclonal Antibody AVP-21D9 to Protective Antigen Reduces Dissemination of the Bacillus anthracis Ames Strain from the Lungs in a Rabbit Model▿

    Science.gov (United States)

    Peterson, Johnny W.; Comer, Jason E.; Baze, Wallace B.; Noffsinger, David M.; Wenglikowski, Autumn; Walberg, Kristin G.; Hardcastle, Jason; Pawlik, Jennifer; Bush, Kathryn; Taormina, Joanna; Moen, Scott; Thomas, John; Chatuev, Bagram M.; Sower, Laurie; Chopra, Ashok K.; Stanberry, Lawrence R.; Sawada, Ritsuko; Scholz, Wolfgang W.; Sircar, Jagadish

    2007-01-01

    Dutch-belted and New Zealand White rabbits were passively immunized with AVP-21D9, a human monoclonal antibody to protective antigen (PA), at the time of Bacillus anthracis spore challenge using either nasal instillation or aerosol challenge techniques. AVP-21D9 (10 mg/kg) completely protected both rabbit strains against lethal infection with Bacillus anthracis Ames spores, regardless of the inoculation method. Further, all but one of the passively immunized animals (23/24) were completely resistant to rechallenge with spores by either respiratory challenge method at 5 weeks after primary challenge. Analysis of the sera at 5 weeks after primary challenge showed that residual human anti-PA levels decreased by 85 to 95%, but low titers of rabbit-specific anti-PA titers were also measured. Both sources of anti-PA could have contributed to protection from rechallenge. In a subsequent study, bacteriological and histopathology analyses revealed that B. anthracis disseminated to the bloodstream in some naïve animals as early as 24 h postchallenge and increased in frequency with time. AVP-21D9 significantly reduced the dissemination of the bacteria to the bloodstream and to various organs following infection. Examination of tissue sections from infected control animals, stained with hematoxylin-eosin and the Gram stain, showed edema and/or hemorrhage in the lungs and the presence of bacteria in mediastinal lymph nodes, with necrosis and inflammation. Tissue sections from infected rabbits dosed with AVP-21D9 appeared comparable to corresponding tissues from uninfected animals despite lethal challenge with B. anthracis Ames spores. Concomitant treatment with AVP-21D9 at the time of challenge conferred complete protection in the rabbit inhalation anthrax model. Early treatment increased the efficacy progressively and in a dose-dependent manner. Thus, AVP-21D9 could offer an adjunct or alternative clinical treatment regimen against inhalation anthrax. PMID:17452469

  13. Human monoclonal antibody AVP-21D9 to protective antigen reduces dissemination of the Bacillus anthracis Ames strain from the lungs in a rabbit model.

    Science.gov (United States)

    Peterson, Johnny W; Comer, Jason E; Baze, Wallace B; Noffsinger, David M; Wenglikowski, Autumn; Walberg, Kristin G; Hardcastle, Jason; Pawlik, Jennifer; Bush, Kathryn; Taormina, Joanna; Moen, Scott; Thomas, John; Chatuev, Bagram M; Sower, Laurie; Chopra, Ashok K; Stanberry, Lawrence R; Sawada, Ritsuko; Scholz, Wolfgang W; Sircar, Jagadish

    2007-07-01

    Dutch-belted and New Zealand White rabbits were passively immunized with AVP-21D9, a human monoclonal antibody to protective antigen (PA), at the time of Bacillus anthracis spore challenge using either nasal instillation or aerosol challenge techniques. AVP-21D9 (10 mg/kg) completely protected both rabbit strains against lethal infection with Bacillus anthracis Ames spores, regardless of the inoculation method. Further, all but one of the passively immunized animals (23/24) were completely resistant to rechallenge with spores by either respiratory challenge method at 5 weeks after primary challenge. Analysis of the sera at 5 weeks after primary challenge showed that residual human anti-PA levels decreased by 85 to 95%, but low titers of rabbit-specific anti-PA titers were also measured. Both sources of anti-PA could have contributed to protection from rechallenge. In a subsequent study, bacteriological and histopathology analyses revealed that B. anthracis disseminated to the bloodstream in some naïve animals as early as 24 h postchallenge and increased in frequency with time. AVP-21D9 significantly reduced the dissemination of the bacteria to the bloodstream and to various organs following infection. Examination of tissue sections from infected control animals, stained with hematoxylin-eosin and the Gram stain, showed edema and/or hemorrhage in the lungs and the presence of bacteria in mediastinal lymph nodes, with necrosis and inflammation. Tissue sections from infected rabbits dosed with AVP-21D9 appeared comparable to corresponding tissues from uninfected animals despite lethal challenge with B. anthracis Ames spores. Concomitant treatment with AVP-21D9 at the time of challenge conferred complete protection in the rabbit inhalation anthrax model. Early treatment increased the efficacy progressively and in a dose-dependent manner. Thus, AVP-21D9 could offer an adjunct or alternative clinical treatment regimen against inhalation anthrax. PMID:17452469

  14. Cell-Based Genotoxicity Testing

    Science.gov (United States)

    Reifferscheid, Georg; Buchinger, Sebastian

    Genotoxicity test systems that are based on bacteria display an important role in the detection and assessment of DNA damaging chemicals. They belong to the basic line of test systems due to their easy realization, rapidness, broad applicability, high sensitivity and good reproducibility. Since the development of the Salmonella microsomal mutagenicity assay by Ames and coworkers in the early 1970s, significant development in bacterial genotoxicity assays was achieved and is still a subject matter of research. The basic principle of the mutagenicity assay is a reversion of a growth inhibited bacterial strain, e.g., due to auxotrophy, back to a fast growing phenotype (regain of prototrophy). Deeper knowledge of the ­mutation events allows a mechanistic understanding of the induced DNA-damage by the utilization of base specific tester strains. Collections of such specific tester strains were extended by genetic engineering. Beside the reversion assays, test systems utilizing the bacterial SOS-response were invented. These methods are based on the fusion of various SOS-responsive promoters with a broad variety of reporter genes facilitating numerous methods of signal detection. A very important aspect of genotoxicity testing is the bioactivation of ­xenobiotics to DNA-damaging compounds. Most widely used is the extracellular metabolic activation by making use of rodent liver homogenates. Again, genetic engineering allows the construction of highly sophisticated bacterial tester strains with significantly enhanced sensitivity due to overexpression of enzymes that are involved in the metabolism of xenobiotics. This provides mechanistic insights into the toxification and detoxification pathways of xenobiotics and helps explaining the chemical nature of hazardous substances in unknown mixtures. In summary, beginning with "natural" tester strains the rational design of bacteria led to highly specific and sensitive tools for a rapid, reliable and cost effective

  15. Gonorrhea Test

    Science.gov (United States)

    ... gonorrhoeae Culture; Neisseria gonorrhoeae Gram Stain; Neisseria gonorrhoeae DNA Probe Related tests: Chlamydia Testing , HIV Antibody and HIV Antigen , Syphilis Tests , Herpes Testing , HPV Test , Trichomonas Testing All content on Lab Tests Online has ...

  16. Simulated rotor test apparatus dynamic characteristics in the 80- by 120-foot wind tunnel

    Science.gov (United States)

    Hoque, M. S.; Peterson, R. L.; Graham, T. A.

    1990-01-01

    A shake test was conducted in the 80 by 120 foot Wind Tunnel at NASA Ames Research Center, using a load frame and dummy weights to simulate the weight of the NASA Rotor Test Apparatus. The simulated hub was excited with broadband random excitation, and accelerometer responses were measured at various locations. The transfer functions (acceleration per unit excitation force as a function of frequency) for each of the accelerometer responses were computed, and the data were analyzed using modal analysis to estimate the model parameters.

  17. Genotoxicity testing of samples generated during UV/H2O2 treatment of surface water for the production of drinking water using the Ames test in vitro and the Comet assay and the SCE test in vivo

    NARCIS (Netherlands)

    Penders, E.J.M.; Martijn, A.J.; Spenkelink, A.; Alink, G.M.; Rietjens, I.; Hoogenboezem, W.

    2012-01-01

    UV/H2O2 treatment can be part of the process converting surface water to drinking water, but would pose a potential problem when resulting in genotoxicity. This study investigates the genotoxicity of samples collected from the water treatment plant Andijk, applying UV/H2O2 treatment with an electric

  18. Computational Analysis of Arc-Jet Wedge Tests Including Ablation and Shape Change

    Science.gov (United States)

    Goekcen, Tahir; Chen, Yih-Kanq; Skokova, Kristina A.; Milos, Frank S.

    2010-01-01

    Coupled fluid-material response analyses of arc-jet wedge ablation tests conducted in a NASA Ames arc-jet facility are considered. These tests were conducted using blunt wedge models placed in a free jet downstream of the 6-inch diameter conical nozzle in the Ames 60-MW Interaction Heating Facility. The fluid analysis includes computational Navier-Stokes simulations of the nonequilibrium flowfield in the facility nozzle and test box as well as the flowfield over the models. The material response analysis includes simulation of two-dimensional surface ablation and internal heat conduction, thermal decomposition, and pyrolysis gas flow. For ablating test articles undergoing shape change, the material response and fluid analyses are coupled in order to calculate the time dependent surface heating and pressure distributions that result from shape change. The ablating material used in these arc-jet tests was Phenolic Impregnated Carbon Ablator. Effects of the test article shape change on fluid and material response simulations are demonstrated, and computational predictions of surface recession, shape change, and in-depth temperatures are compared with the experimental measurements.

  19. Susceptibility Testing

    Science.gov (United States)

    ... page helpful? Also known as: Sensitivity Testing; Drug Resistance Testing; Culture and Sensitivity; C & S; Antimicrobial Susceptibility Formal name: Bacterial and Fungal Susceptibility Testing Related tests: Urine Culture ; ...

  20. Advancing Test Capabilities at NASA Wind Tunnels

    Science.gov (United States)

    Bell, James

    2015-01-01

    NASA maintains twelve major wind tunnels at three field centers capable of providing flows at 0.1 M 10 and unit Reynolds numbers up to 45106m. The maintenance and enhancement of these facilities is handled through a unified management structure under NASAs Aeronautics and Evaluation and Test Capability (AETC) project. The AETC facilities are; the 11x11 transonic and 9x7 supersonic wind tunnels at NASA Ames; the 10x10 and 8x6 supersonic wind tunnels, 9x15 low speed tunnel, Icing Research Tunnel, and Propulsion Simulator Laboratory, all at NASA Glenn; and the National Transonic Facility, Transonic Dynamics Tunnel, LAL aerothermodynamics laboratory, 8 High Temperature Tunnel, and 14x22 low speed tunnel, all at NASA Langley. This presentation describes the primary AETC facilities and their current capabilities, as well as improvements which are planned over the next five years. These improvements fall into three categories. The first are operations and maintenance improvements designed to increase the efficiency and reliability of the wind tunnels. These include new (possibly composite) fan blades at several facilities, new temperature control systems, and new and much more capable facility data systems. The second category of improvements are facility capability advancements. These include significant improvements to optical access in wind tunnel test sections at Ames, improvements to test section acoustics at Glenn and Langley, the development of a Supercooled Large Droplet capability for icing research, and the development of an icing capability for large engine testing. The final category of improvements consists of test technology enhancements which provide value across multiple facilities. These include projects to increase balance accuracy, provide NIST-traceable calibration characterization for wind tunnels, and to advance optical instruments for Computational Fluid Dynamics (CFD) validation. Taken as a whole, these individual projects provide significant

  1. Propiedades Mecánicas y Viscoelásticas del Ñame (Dioscórea alata Mechanical and Viscoelastic Properties of Yam (Dioscórea Alata

    Directory of Open Access Journals (Sweden)

    Armando Alvis

    2009-01-01

    Full Text Available En el presente trabajo se midieron algunas de las principales propiedades mecánicas y características viscoelásticas de dos variedades de ñame, con el objetivo de obtener los datos necesarios para determinados cálculos de ingeniería de procesos, manipulación y almacenamiento del producto. Se utilizaron diferentes pruebas (penetración, compresión uniaxial y flexión o doblado, para calcular los parámetros: esfuerzo máximo de penetración, esfuerzo y deformación en la fractura, módulo de deformabilidad y las constantes “a” y “b” del modelo normalizado y linealizado de Peleg. Se concluye que la variedad Pico Botella presenta valores más elevados del esfuerzo de fractura (0.57 MPa que la Diamante 22 (0.31 MPa y que además la deformación a que debe someterse para provocar la fractura es también muy superior (32 % vs. 21 %. Sin embargo, en cuanto a las constantes del modelo viscoelástico de Peleg no existen prácticamente diferencias, alcanzando ambas variedades valores iguales del esfuerzo asintótico a = 0.43 y muy similares para la velocidad de relajación del esfuerzo, lo cual indica que la estructura de ambas es muy parecidas.In the present study were measured some of the major mechanical properties and viscoelastic characteristics of two different varieties of yams, with the objetive of obtaining the data needed for certain calculations of process engineering, handling and storage of the product. Using an Instron machine, some different tests has been applied: puncture, uniaxial compression and bending in order to calculate the parameters: maximum stress of penetration, stress and strain at fracture, deformability modulus and the constants “a” and “b” from the Peleg model. It is concluded that the Pico de Botella cultivar has a fracture stress higher (0.57 MPA than the Diamante 22cultivar (0.31 MPa and also the degree of deformation at fracture is higher (32 % versus 21 %. In relation with the constants from the

  2. Direct genotoxicity and mutagenicity of endodontic substances and materials as evaluated by two prokaryotic test systems Genotoxicidade e mutagenicidade diretas de substâncias e materiais endodônticos avaliadas por dois testes procariotas

    Directory of Open Access Journals (Sweden)

    Sérgio Márcio Motta Gahyva

    2005-12-01

    Full Text Available Substances and materials used in endodontic therapy come into close contact with the periradicular tissues via apical foramen and foramina. Consequently, they should possess biocompatibility. There are currently few studies describing the genotoxic and mutagenic potentials of substances and materials used in endodontics. The purpose of this study was to evaluate the direct genotoxic and mutagenic properties of several substances and materials used in different phases of the endodontic treatment. For this intent, two prokaryotic test systems were used: the SOS chromotest and the Ames test. No metabolization with S9 was investigated, since only the direct effects of the substances and materials were surveyed. Most of the substances and materials tested presented mild to moderate cytotoxicity and genotoxicity as revealed by the SOS chromotest. Formocresol was the only tested substance to present severe genotoxicity to the tester bacterial strains. However, no substance or material tested showed direct mutagenicity as revealed by the Ames test.Substâncias e materiais utilizados na terapia endodôntica entram em íntimo contato com os tecidos perirradiculares via forame apical e foraminas e, em decorrência disto, deveriam idealmente possuir as seguintes características: biocompatibilidade e ausência de mutagenicidade. Existem poucos estudos avaliando o potencial genotóxico e mutagênico de substâncias e materiais utilizados em Endodontia. Este estudo avaliou os efeitos citotóxicos, genotóxicos e mutagênicos diretos de várias substâncias e materiais utilizados em diferentes etapas do tratamento endodôntico. Para isto, dois sistemas procarióticos foram usados: o SOS chromotest e o teste de Ames. Metabolização com fração S9 não foi realizada, uma vez que tencionou-se avaliar os efeitos diretos das substâncias e materiais. Os resultados demonstraram que algumas substâncias e materiais foram citotóxicos e/ou genotóxicos no SOS

  3. Prenatal Tests

    Science.gov (United States)

    ... Close X Home > Pregnancy > Prenatal care > Prenatal tests Prenatal tests E-mail to a friend Please fill ... even if you’re feeling fine. What are prenatal tests? Prenatal tests are medical tests you get ...

  4. Trichomonas Testing

    Science.gov (United States)

    ... vaginalis by Direct Fluorescent Antibody (DFA) Related tests: Pap Smear , Chlamydia Testing , Gonorrhea Testing At a Glance Test ... during a routine gynecologic examination that includes a Pap smear . An FDA-cleared PCR test approved for detection ...

  5. Pinworm test

    Science.gov (United States)

    Oxyuriasis test; Enterobiasis test; Tape test ... diagnose this infection is to do a tape test. The best time to do this is in ... to determine if there are eggs. The tape test may need to be done on 3 separate ...

  6. Seismic testing

    International Nuclear Information System (INIS)

    This lecture deals with: qualification methods for seismic testing; objectives of seismic testing; seismic testing standards including examples; main content of standard; testing means; and some important elements of seismic testing

  7. Characteristics of the NASA-Ames Laminar Flow Supersonic Wind Tunnel for Unique Mach 1.6 Transition Studies

    Science.gov (United States)

    Wolf, Stephen W. D.; Laub, James A.

    1997-01-01

    Flow quality measurements have been performed in the unique Laminar Flow Supersonic Wind Tunnel (LFSWT) to examine both mean and dynamic characteristics. The intent was to provide the necessary flow information about this ground test facility, to support meaningful transition research at Mach 1.6 and flight unit Reynolds numbers. This paper is intended to assist other experimentalists with similar goals of characterizing low-supersonic test environments. An array of instrumentation has been used to highlight the importance of proper selection of pressure instruments and data acquisition procedures. We conclude that the test section is low-disturbance (based on classical standards of pressure disturbances less than 0.1% with no specified data bandwidth), and has uniform flow. This is confirmation that the quiet design features of the LFSWT are effective. However, characterization of the test section flow over a 0.25k-5Ok bandwidth shows that the disturbance levels can be greater than classical standards particularly for stagnation pressures less than 9.5 psia (0.65 bar) with low stagnation temperatures. Variability of the flow disturbances in the settling chamber and test section is contained in a narrow frequency bandwidth below 5k Hz, which is associated with resonant frequencies from the pressure reduction system. So far, these disturbances have not impacted transition along the tunnel walls or a 10 degrees cone. However, continual vigilance is required to maintain a known low-disturbance environment for transition research in the LFSWT. Furthermore, the formation of standards for flow quality measurements is strongly recommended, so that transition research can be better isolated from tunnel disturbances.

  8. Ames Imaging Library System- A Source of NASA's Images & Photos%艾姆斯图像数字图书馆:带你寻找太空的奥秘

    Institute of Scientific and Technical Information of China (English)

    刘燕权; 杨皓东; 江凌; 迟凯; 赵锐

    2011-01-01

    艾姆斯(Ames)图像数字图书馆旨在记录并提供美国航天局(NASA)艾姆斯研究中心在众多开发项目和活动中所拍摄的照片和图像.作为NASA资助的数字图书馆项目之一,该馆面向学生、教育工作者、科学家等广大用户,使其成为他们学习研究有关宇航影像的信息资源中心.文章从资源组织、服务特征、界面设计等方面对AILS作了概要评述,同时给出了笔者的评价与建议.%Ames Imaging Library System (AILS) is a living collection of still images that chronicles the projects and activities of the US NASA's Ames Research Center, intending to be a source for students, educators, scientists and interesting parties to learn/retrieve related image & photo objects. This paper provides an overview of the major development of its digital collection and organization, service provided and interface designed Authors' comments and suggestions are also given.

  9. Multilayer Pressure Vessel Materials Testing and Analysis. Phase 1

    Science.gov (United States)

    Cardinal, Joseph W.; Popelar, Carl F.; Page, Richard A.

    2014-01-01

    To provide NASA a comprehensive suite of materials strength, fracture toughness and crack growth rate test results for use in remaining life calculations for aging multilayer pressure vessels, Southwest Research Institute (R) (SwRI) was contracted in two phases to obtain relevant material property data from a representative vessel. This report describes Phase 1 of this effort which includes a preliminary material property assessment as well as a fractographic, fracture mechanics and fatigue crack growth analyses of an induced flaw in the outer shell of a representative multilayer vessel that was subjected to cyclic pressure test. SwRI performed this Phase 1 effort under contract to the Digital Wave Corporation in support of their contract to Jacobs ATOM for the NASA Ames Research Center.

  10. Low Speed PSP Testing in Production Wind Tunnels

    Science.gov (United States)

    Bell, James; Mehta, Rabi; Schairer, Ed; Hand, Larry; Nixon, David (Technical Monitor)

    1998-01-01

    The brightness signal from a pressure-sensitive paint varies inversely with absolute pressure. Consequently high signal-to-noise ratios are required to resolve aerodynamic pressure fields at low speeds, where the pressure variation around an object might only be a few percent of the mean pressure. This requirement is unavoidable, and implies that care must be taken to minimize noise sources present in the measurement. This paper discusses and compares the main noise sources in low speed PSP testing using the "classical" intensity-based single-luminophore technique. These are: temperature variation, model deformation, and lamp drift/paint degradation. Minimization of these error sources from the point of view of operation in production wind tunnels is discussed, with some examples from recent tests in NASA Ames facilities.

  11. Test Under Test

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    China’s national college entrance examination, regarded as a make-or-break test by many students, leaves much to be desired “We’ve bribed the exam supervisors, paying each one 20,000 yuan. They will make everything go smooth during the exams,” Li Feng, a teacher from No.2 High School in

  12. Graphene for Preconcentration of Trace Amounts of Ni in Water and Paraffin-Embedded Tissues from Liver Loggerhead Turtles Specimens Prior to flame Atomic Absorption Spectrometry

    Directory of Open Access Journals (Sweden)

    Hanie Arbabi Rashid

    2014-03-01

    Full Text Available A new sensitive and simple method was developed for the preconcentration of trace amounts of Ni using 1-(2-pyridylazo-2-naphthol (PAN as chelating reagent prior to its determination by flame atomic absorption spectrometry. The proposed method is based on the uti- lization of a column packed with graphene as sorbent. Several effective parameters on the extraction and complex formation were selected and optimized. Under optimum conditions, the calibration graph was linear in the concentration range of 5.0–240.0 µg L-1 with a detection limit of 0.36 µg L-1. The relative standard deviation for ten replicate measurements of 20.0 and 100.0 µg L-1 of Ni were 3.45 and 3.18%, respectively. Comparative studies showed that graphene is superior to other adsorbents including C18 silica, graphitic carbon, and single- and multi-walled carbon nanotubes for the extraction of Ni. In the present study, we report the application of preconcentration techniques still continues increasingly for trace metal determinations by flame atomic absorption spectrometry (FAAS for quantification of Ni in Formalin-fixed paraffin-embedded (FFPE tissues from Liver loggerhead turtles. The proposed method was successfully applied in the analysis of four real environmental water samples. Good spiked recoveries over the range of 95.8–102.6% were obtained.

  13. The Formation of Solid Particles from their Gas-Phase Molecular Precursors in Cosmic Environments with NASA Ames' COSmIC Facility

    Science.gov (United States)

    Salama, Farid

    2014-01-01

    We present and discuss the unique characteristics and capabilities of the laboratory facility, COSmIC, that was developed at NASA Ames to generate, process and analyze interstellar, circumstellar and planetary analogs in the laboratory. COSmIC stands for Cosmic Simulation Chamber and is dedicated to the study of molecules and ions under the low temperature and high vacuum conditions that are required to simulate interstellar, circumstellar and planetary physical environments in space. COSmIC integrates a variety of state-of-the-art instruments that allow forming, processing and monitoring simulated space conditions for planetary, circumstellar and interstellar materials in the laboratory. COSmIC is composed of a Pulsed Discharge Nozzle (PDN) expansion that generates a free jet supersonic expansion coupled to two ultrahigh-sensitivity, complementary in situ diagnostics: a Cavity Ring Down Spectroscopy (CRDS) system for photonic detection and a Reflectron Time-Of-Flight Mass Spectrometer (ReTOF-MS) for mass detection. Recent, unique, laboratory astrophysics results that were obtained using the capabilities of COSmIC will be discussed, in particular the progress that have been achieved in monitoring in the laboratory the formation of solid gains from their gas-phase molecular precursors in environments as varied as stellar/circumstellar outflow and planetary atmospheres. Plans for future, next generation, laboratory experiments on cosmic molecules and grains in the growing field of laboratory astrophysics will also be addressed as well as the implications of these studies for current and upcoming space missions.

  14. Analysis and characterization of heavy residues produced in 129Xe + natSn reactions between 8 and 25 AMeV

    International Nuclear Information System (INIS)

    Studies with the INDRA multidetector of the 129Xe + natSn reactions showed the unexpected existence of heavy fragments with a charge as large as Z=70. The charges of Xe and Sn are 54 and 50 respectively. Reactions between nuclei with a charge product greater than 2700 are dominated by deep inelastic collisions. For Xe + Sn the product is exactly 2700. After these observations, 129Xe + natSn reactions at 8, 12, 15, 20 and 25 AMeV have been done. It will then be possible to clarify if the heavy residues are formed by an incomplete fusion, massive transfers occurring in deep inelastic collisions or a very asymmetric fission of a compound system. This work will present experimental results obtained by the analysis of these experiments. We will show that heavy residues are formed with a production cross-section of 10-2 mb. Angular distributions show that the residues can be produced by an incomplete fusion of the projectile and the target. The study of the products in coincidence with the residues shows that a compound system was formed, followed by a fission producing the residue and a lighter fragment. The comparison with a phenomenological model, HIPSE, confirms that the model is valid at these energies

  15. Experimental Investigations of the NASA Common Research Model in the NASA Langley National Transonic Facility and NASA Ames 11-Ft Transonic Wind Tunnel (Invited)

    Science.gov (United States)

    Rivers, S. M.; Dittberner, Ashley

    2011-01-01

    Experimental aerodynamic investigations of the NASA Common Research Model have been conducted in the NASA Langley National Transonic Facility and the NASA Ames 11-ft wind tunnel. Data have been obtained at chord Reynolds numbers of 5 million for five different configurations at both wind tunnels. Force and moment, surface pressure and surface flow visualization data were obtained in both facilities but only the force and moment data are presented herein. Nacelle/pylon, tail effects and tunnel to tunnel variations have been assessed. The data from both wind tunnels show that an addition of a nacelle/pylon gave an increase in drag, decrease in lift and a less nose down pitching moment around the design lift condition of 0.5 and that the tail effects also follow the expected trends. Also, all of the data shown fall within the 2-sigma limits for repeatability. The tunnel to tunnel differences are negligible for lift and pitching moment, while the drag shows a difference of less than ten counts for all of the configurations. These differences in drag may be due to the variation in the sting mounting systems at the two tunnels.

  16. Multiplicación in vitro de segmentos nodales del clon de ñame Blanco de Guinea (Dioscorea cayenensis - D. rotundata en sistemas de cultivo semiautomatizado

    Directory of Open Access Journals (Sweden)

    Manuel Cabrera Jova

    2009-01-01

    Full Text Available Con el empleo del sistema de inmersión temporal fue posible incrementar la multiplicación in vitro de los segmentos nodales en el clon de ñame Blanco de Guinea. Con este tipo de sistema de cultivo se obtuvieron los más altos valores para la altura de la planta, número de entrenudos por planta, así como para la masa fresca y seca de las mismas. Las condiciones de cultivo creadas en el sistema de inmersión temporal para la multiplicación in vitro de los segmentos nodales lograron el más alto coeficiente de multiplicación (8,50, así como redujeron el número de plantas con síntomas de vitrificación (3,30. Las plantas cultivadas en este tipo de sistema de cultivo se caracterizaron por el mayor crecimiento de los segmentos nodales, coloración verde y hojas más desarrolladas. La utilización de este tipo de sistema de cultivo en la fase de multiplicación in vitro de los segmentos nodales posibilitará incrementar el empleo de la micropropagación para la producción de semilla en el complejo Dioscorea cayenensis - D. rotundata. Palabras clave: sistema de inmersión temporal; medio líquido; micropropagación; temporary immersion system; liquid medium; micropropagation.

  17. Understanding transport simulations of heavy-ion collisions at 100 and 400 AMeV: Comparison of heavy ion transport codes under controlled conditions

    CERN Document Server

    Xu, Jun; Tsang, ManYee Betty; Wolter, Hermann; Zhang, Ying-Xun; Aichelin, Joerg; Colonna, Maria; Cozma, Dan; Danielewicz, Pawel; Feng, Zhao-Qing; Fevre, Arnaud Le; Gaitanos, Theodoros; Hartnack, Christoph; Kim, Kyungil; Kim, Youngman; Ko, Che-Ming; Li, Bao-An; Li, Qing-Feng; Li, Zhu-Xia; Napolitani, Paolo; Ono, Akira; Papa, Massimo; Song, Taesoo; Su, Jun; Tian, Jun-Long; Wang, Ning; Wang, Yong-Jia; Weil, Janus; Xie, Wen-Jie; Zhang, Feng-Shou; Zhang, Guo-Qiang

    2016-01-01

    Transport simulations are very valuable for extracting physics information from heavy-ion collision experiments. With the emergence of many different transport codes in recent years, it becomes important to estimate their robustness in extracting physics information from experiments. We report on the results of a transport code comparison project. 18 commonly used transport codes were included in this comparison: 9 Boltzmann-Uehling-Uhlenbeck-type codes and 9 Quantum-Molecular-Dynamics-type codes. These codes have been required to simulate Au+Au collisions using the same physics input for mean fields and for in-medium nucleon-nucleon cross sections, as well as the same initialization set-up, the impact parameter, and other calculational parameters at 100 and 400 AMeV incident energy. Among the codes we compare one-body observables such as rapidity and transverse flow distributions. We also monitor non-observables such as the initialization of the internal states of colliding nuclei and their stability, the co...

  18. Proposed Use of the NASA Ames Nebula Cloud Computing Platform for Numerical Weather Prediction and the Distribution of High Resolution Satellite Imagery

    Science.gov (United States)

    Limaye, Ashutosh S.; Molthan, Andrew L.; Srikishen, Jayanthi

    2010-01-01

    The development of the Nebula Cloud Computing Platform at NASA Ames Research Center provides an open-source solution for the deployment of scalable computing and storage capabilities relevant to the execution of real-time weather forecasts and the distribution of high resolution satellite data to the operational weather community. Two projects at Marshall Space Flight Center may benefit from use of the Nebula system. The NASA Short-term Prediction Research and Transition (SPoRT) Center facilitates the use of unique NASA satellite data and research capabilities in the operational weather community by providing datasets relevant to numerical weather prediction, and satellite data sets useful in weather analysis. SERVIR provides satellite data products for decision support, emphasizing environmental threats such as wildfires, floods, landslides, and other hazards, with interests in numerical weather prediction in support of disaster response. The Weather Research and Forecast (WRF) model Environmental Modeling System (WRF-EMS) has been configured for Nebula cloud computing use via the creation of a disk image and deployment of repeated instances. Given the available infrastructure within Nebula and the "infrastructure as a service" concept, the system appears well-suited for the rapid deployment of additional forecast models over different domains, in response to real-time research applications or disaster response. Future investigations into Nebula capabilities will focus on the development of a web mapping server and load balancing configuration to support the distribution of high resolution satellite data sets to users within the National Weather Service and international partners of SERVIR.

  19. Multidimensional Tests of Thermal Protection Materials in the Arcjet Test Facility

    Science.gov (United States)

    Agrawal, Parul; Ellerby, Donald T.; Switzer, Mathew R.; Squire, Thomas H.

    2010-01-01

    Many thermal protection system materials used for spacecraft heatshields have anisotropic thermal properties, causing them to display significantly different thermal characteristics in different directions, when subjected to a heating environment during flight or arcjet tests. This paper investigates the effects of sidewall heating coupled with anisotropic thermal properties of thermal protection materials in the arcjet environment. Phenolic Impregnated Carbon Ablator (PICA) and LI-2200 materials (the insulation material of Shuttle tiles) were used for this study. First, conduction-based thermal response simulations were carried out, using the Marc.Mentat finite element solver, to study the effects of sidewall heating on PICA arcjet coupons. The simulation showed that sidewall heating plays a significant role in thermal response of these models. Arcjet tests at the Aerodynamic Heating Facility (AHF) at NASA Ames Research Center were performed later on instrumented coupons to obtain temperature history at sidewall and various radial locations. The details of instrumentation and experimental technique are the prime focus of this paper. The results obtained from testing confirmed that sidewall heating plays a significant role in thermal response of these models. The test results were later used to verify the two-dimensional ablation, thermal response, and sizing program, TITAN. The test data and model predictions were found to be in excellent agreement

  20. Multidimensional Testing of Thermal Protection Materials in the Arcjet Test Facility

    Science.gov (United States)

    Agrawal, Parul; Ellerby, Donald T.; Switzer, Matt R.; Squire, Thomas Howard

    2010-01-01

    Many thermal protection system materials used for spacecraft heatshields have anisotropic thermal properties, causing them to display significantly different thermal characteristics in different directions, when subjected to a heating environment during flight or arcjet tests. The anisotropic effects are enhanced in the presence of sidewall heating. This paper investigates the effects of anisotropic thermal properties of thermal protection materials coupled with sidewall heating in the arcjet environment. Phenolic Impregnated Carbon Ablator (PICA) and LI-2200 materials (the insulation material of Shuttle tiles) were used for this study. First, conduction-based thermal response simulations were carried out, using the Marc.Mentat finite element solver, to study the effects of sidewall heating on PICA arcjet coupons. The simulation showed that sidewall heating plays a significant role in thermal response of these models. Arcjet tests at the Aerodynamic Heating Facility (AHF) at NASA Ames Research Center were performed later on instrumented coupons to obtain temperature history at sidewall and various radial locations. The details of instrumentation and experimental technique are the prime focus of this paper. The results obtained from testing confirmed that sidewall heating plays a significant role in thermal response of these models. The test results were later used to validate the two-dimensional ablation, thermal response, and sizing program, TITAN. The test data and model predictions were found to be in excellent agreement

  1. Nano-ADEPT Aeroloads Wind Tunnel Test

    Science.gov (United States)

    Smith, Brandon; Yount, Bryan; Kruger, Carl; Brivkalns, Chad; Makino, Alberto; Cassell, Alan; Zarchi, Kerry; McDaniel, Ryan; Ross, James; Wercinski, Paul; Venkatapathy, Ethiraj; Swanson, Gregory; Gold, Nili

    2016-01-01

    A wind tunnel test of the Adaptable Deployable Entry and Placement Technology (ADEPT) was conducted in April 2015 at the US Army's 7 by10 Foot Wind Tunnel located at NASA Ames Research Center. Key geometric features of the fabric test article were a 0.7 meter deployed base diameter, a 70 degree half-angle forebody cone angle, eight ribs, and a nose-to-base radius ratio of 0.7. The primary objective of this wind tunnel test was to obtain static deflected shape and pressure distributions while varying pretension at dynamic pressures and angles of attack relevant to entry conditions at Earth, Mars, and Venus. Other objectives included obtaining aerodynamic force and moment data and determining the presence and magnitude of any dynamic aeroelastic behavior (buzz/flutter) in the fabric trailing edge. All instrumentation systems worked as planned and a rich data set was obtained. This paper describes the test articles, instrumentation systems, data products, and test results. Four notable conclusions are drawn. First, test data support adopting a pre-tension lower bound of 10 foot pounds per inch for Nano-ADEPT mission applications in order to minimize the impact of static deflection. Second, test results indicate that the fabric conditioning process needs to be reevaluated. Third, no flutter/buzz of the fabric was observed for any test condition and should also not occur at hypersonic speeds. Fourth, translating one of the gores caused ADEPT to generate lift without the need for a center of gravity offset. At hypersonic speeds, the lift generated by actuating ADEPT gores could be used for vehicle control.

  2. Coombs test

    Science.gov (United States)

    Direct antiglobulin test; Indirect antiglobulin test; Anemia - hemolytic ... No special preparation is necessary for this test. ... There are 2 types of the Coombs test: Direct Indirect The direct ... that are stuck to the surface of red blood cells. Many diseases ...

  3. Test Anxiety

    Science.gov (United States)

    ... Can I Help a Friend Who Cuts? Test Anxiety KidsHealth > For Teens > Test Anxiety Print A A ... with their concentration or performance. What Is Test Anxiety? Test anxiety is actually a type of performance ...

  4. Coombs test

    Science.gov (United States)

    Direct antiglobulin test; Indirect antiglobulin test ... No special preparation is necessary for this test. ... There are two types of the Coombs test: Direct Indirect The ... that are stuck to the surface of red blood cells. Many diseases ...

  5. Large-scale V/STOL testing. [in wind tunnels

    Science.gov (United States)

    Koenig, D. G.; Aiken, T. N.; Aoyagi, K.; Falarski, M. D.

    1977-01-01

    Several facets of large-scale testing of V/STOL aircraft configurations are discussed with particular emphasis on test experience in the Ames 40- by 80-foot wind tunnel. Examples of powered-lift test programs are presented in order to illustrate tradeoffs confronting the planner of V/STOL test programs. It is indicated that large-scale V/STOL wind-tunnel testing can sometimes compete with small-scale testing in the effort required (overall test time) and program costs because of the possibility of conducting a number of different tests with a single large-scale model where several small-scale models would be required. The benefits of both high- and full-scale Reynolds numbers, more detailed configuration simulation, and number and type of onboard measurements increase rapidly with scale. Planning must be more detailed at large scale in order to balance the trade-offs between the increased costs, as number of measurements and model configuration variables increase and the benefits of larger amounts of information coming out of one test.

  6. Configuration management issues and objectives for a real-time research flight test support facility

    Science.gov (United States)

    Yergensen, Stephen; Rhea, Donald C.

    1988-01-01

    Presented are some of the critical issues and objectives pertaining to configuration management for the NASA Western Aeronautical Test Range (WATR) of Ames Research Center. The primary mission of the WATR is to provide a capability for the conduct of aeronautical research flight test through real-time processing and display, tracking, and communications systems. In providing this capability, the WATR must maintain and enforce a configuration management plan which is independent of, but complimentary to, various research flight test project configuration management systems. A primary WATR objective is the continued development of generic research flight test project support capability, wherein the reliability of WATR support provided to all project users is a constant priority. Therefore, the processing of configuration change requests for specific research flight test project requirements must be evaluated within a perspective that maintains this primary objective.

  7. Results from the EPL monkey-pod flight experiments conducted aboard the NASA/Ames CV-990, May 1976

    Science.gov (United States)

    Rahlmann, D. F.; Kodama, A. M.; Mains, R. C.; Pace, N.

    1976-01-01

    The participation of the Environmental Physiology Laboratory (EPL) in the general purpose laboratory concept verification test 3 is documented. The EPL Monkey-Pod Experiment was designed to incorporate a 10-12 kg, pig tailed monkey, Macaca nemestrina, into the pod and measure the physiological responses of the animal continously. Four major elements comprise the EPL Monkey-Pod Experiment System: (1) a fiberglass pod containing the instrumented monkey plus feeder and watering devices, (2) an inner console containing the SKYLAB mass spectrometer with its associated valving and electronic controls, sensing, control and monitoring units for lower body negative pressure, feeder activity, waterer activity, temperatures, and gas metabolism calibration, (3) an umbilical complex comprising gas flow lines and electrical cabling between the inner and outer console and (4) an outer console in principle representing the experiment support to be provided from general space craft sources.

  8. Results from the EPL monkey-pod experiment conducted as part of the 1974 NASA/Ames shuttle CVT-2

    Science.gov (United States)

    Rahlmann, D. F.; Kodama, A. M.; Mains, R. C.; Pace, N.

    1974-01-01

    The participation of the Environmental Physiology Laboratory (EPL) in the general purpose laboratory concept verification test 3 is documented. The EPL Monkey-Pod Experiment was designed to incorporate a 10-12 kg, pig tailed monkey, Macaca nemestrina, into the pod and measure the physiological responses of the animal continuously. Four major elements comprise the EPL Monkey-Pod Experiment System: (1) a fiberglass pod containing the instrumented monkey plus feeder and watering devices, (2) an inner console containing the SKYLAB mass spectrometer with its associated valving and electronic controls, sensing, control and monitoring units for lower body negative pressure, feeder activity, waterer activity, temperatures, and gas metabolism calibration, (3) an umbilical complex comprising gas flow lines and electrical cabling between the inner and outer console and (4) an outer console in principle representing the experiment support to be provided from general spacecraft sources.

  9. Aging material evaluation and studies by non-destructive techniques (AMES-NDT) - a European network project

    International Nuclear Information System (INIS)

    This paper presents results obtained in a round-robin action organized in a concerted action of ten partners in the EURATOM program of the European Community. The objective of the research was to document the state of the art of available non-destructive testing (NDT) techniques in order to characterize material aging phenomena based on a reduction of Charpy-V energy and a shift in the fracture appearance transition temperature. Therefore, samples from the Japanese nuclear reactor pressure vessel JRQ-steel (ASMT Standard A533-B Class 1) have been thermally treated at 700 deg. C for 18 h with a subsequent water quenching. Besides micromagnetic and electromagnetic NDT, the positron annihilation technique, ultrasonic reverberation by using Laser ultrasonics and the thermo-electrical power have been applied to characterize the aged material states

  10. El diagnóstico genético del sexo mediante el test de la amelogenina: Métodos y posibles fuentes de error Sex typing through the Amelogenin test: Methods and possible pitfalls

    Directory of Open Access Journals (Sweden)

    F. Francès

    2008-04-01

    Full Text Available El diagnóstico del sexo a partir de indicios biológicos es crucial en la ciencia forense en general y en la investigación criminal, en particular. La amelogenina -proteina codificada en los cromosomas sexuales- se viene utilizando con ese fin desde la última década del siglo pasado. Existen divergencias en secuencia y tamaño entre los alelos codificados en el cromosoma X y el cromosoma Y (AMELX y AMELY, respectivamente. Esta es la base que ha permitido su amplia utilización en ciencias forenses para el diagnóstico genético del sexo. No obstante, recientemente se han publicado casos en los cuales el resultado del test de la amelogenina no corresponde con el sexo legal (oficial del individuo. El presente trabajo presenta una revisión de los protocolos publicados, localizando las áreas más comúnmente amplificadas del gen de la amelogenina, así como de las técnicas utilizadas para la detección de los fragmentos amplificados de AMELX y AMELY. Por último se analizan las condiciones en las cuales el test de la amelogenina, puede mostrarse discrepante con el sexo fenotípico del individuo y que han de ser tenidas en cuenta para evitar errores potencialmente graves en el curso de la investigación con fines forenses.Sex typing of biological evidences is crucial in forensics in general, and in criminal investigation, in particular. The amelogenin -a protein codified in the sexual chromosomes- has been used with these purposes since the last decade of the past century. There are sequence and size divergences between the X and Y-codified alleles of this gene (AMELX and AMELY. This fact is in the base of its using as a genetic sex typing test. However some cases in which the amelogenin test outcome does not correspond with the legal (official sex have been published. The present work offers a revision of the published protocols of the amelogenin sex typing test, locating the most common amplified areas of this gene, and the different

  11. Evaluación de métodos para la conservación de hongos fitopatógenos del ñame (Dioscorea sp.

    Directory of Open Access Journals (Sweden)

    Yeimy Alexandra Pinzón Gutiérrez

    2009-12-01

    Full Text Available Un elemento esencial en la investigación con microorganismos fitopatógenos es su conservación y uso seguro. Desde este punto de vista, en este estudio se evaluaron métodos de conservación de hongos que atacan el ñame, empleando como factores de respuesta el potencial de viabilidad, y la estabilidad y presencia o ausencia de cambios en las características macro y microscópicas. Como resultado del trabajo se proponen los métodos más adecuados para los géneros Colletotrichum y Fusarium, hongos causantes de las mayores pérdidas en las plantaciones de ñame en la Costa Caribe colombiana. Las cepas utilizadas en este estudio provienen de las colecciones de la Universidad de Sucre, del Instituto de Biotecnología de la Universidad Nacional de Colombia (IBUN y de una donación de la doctora Lucía Afanador de la Universidad Nacional, Sede Medellín. Estas fueron sometidas a diferentes métodos de conservación, entre ellos criopreservación, liofilización y cultivo periódico con y sin aceite mineral. Los resultados obtenidos permitieron elegir la criopreservación como el método más eficiente para la conservación de la colección, y el cultivo periódico con aceite mineral como método alternativo y complementario. Estos minimizan el riesgo de pérdida del material biológico y brindan condiciones de manejo que conservan las características biológicas bajo estudio desde campos como la microbiología, la bioquímica y la biología molecular, entre otros. Palabras clave: criopreservación; liofilización; cultivo periódico; Colletotrichum sp.; Fusarium sp. Abstract: An essential element in phytopathogenic microorganism research is their preservation and safe use. The purpose of this study was to evaluate methods for preserving fungi producing diseases in yam, using potential viability, stability and the presence or absence of macro- and microscopic characteristic changes as response factors. More suitable methods for Colletotrichum and

  12. Inhalational anthrax (Ames aerosol in naive and vaccinated New Zealand rabbits: characterizing the spread of bacteria from lung deposition to bacteremia.

    Directory of Open Access Journals (Sweden)

    Bradford eGutting

    2012-06-01

    Full Text Available There is a need to better understand inhalational anthrax in relevant animal models. This understanding could aid risk assessment, help define therapeutic windows, and provide a better understanding of disease. The aim here was to characterize and quantify bacterial deposition and dissemination in rabbits following exposure to single high aerosol dose (>100LD50 of Bacillus anthracis (Ames spores immediately following exposure through 36 hours. The primary goal of collecting the data was to support investigators in developing computational models of inhalational anthrax disease. Rabbits were vaccinated prior to exposure with the human vaccine (Anthrax Vaccine Adsorbed, AVA or were sham-vaccinated, and were then exposed in pairs (1 sham and 1 AVA so disease kinetics could be characterized in equally-dosed hosts where one group is fully protected and is able to clear the infection (AVA-vaccinated, while the other is susceptible to disease, in which case the bacteria are able to escape containment and replicate uncontrolled (sham-vaccinated rabbits. Between 4-5% of the presented aerosol dose was retained in the lung of sham- and AVA-vaccinated rabbits as measured by dilution plate analysis of homogenized lung tissue or bronchoalveolar lavage (BAL fluid. After 6 and 36 hours, >80% and >96%, respectively, of the deposited spores were no longer detected in BAL, with no detectable difference between sham- or AVA-vaccinated rabbits. Thereafter, differences between the two groups became noticeable. In sham-vaccinated rabbits the bacteria were detected in the tracheobronchial lymph nodes (TBLN 12 hours post exposure and in the circulation at 24 hours, a time point which was also associated with dramatic increases in vegetative CFU in the lung tissue of some animals. In all sham-vaccinated rabbits, bacteria increased in both TBLN and blood through 36 hours at which point in time some rabbits succumbed to disease. In contrast, AVA-vaccinated rabbits showed

  13. The Mars Dust Cycle: Investigating the Effects of Radiatively Active Water Ice Clouds on Surface Stresses and Dust Lifting Potential with the NASA Ames Mars General Circulation Model

    Science.gov (United States)

    Kahre, Melinda A.; Hollingsworth, Jeffery

    2012-01-01

    The dust cycle is a critically important component of Mars' current climate system. Dust is present in the atmosphere of Mars year-round but the dust loading varies with season in a generally repeatable manner. Dust has a significant influence on the thermal structure of the atmosphere and thus greatly affects atmospheric circulation. The dust cycle is the most difficult of the three climate cycles (CO2, water, and dust) to model realistically with general circulation models. Until recently, numerical modeling investigations of the dust cycle have typically not included the effects of couplings to the water cycle through cloud formation. In the Martian atmosphere, dust particles likely provide the seed nuclei for heterogeneous nucleation of water ice clouds. As ice coats atmospheric dust grains, the newly formed cloud particles exhibit different physical and radiative characteristics. Thus, the coupling between the dust and water cycles likely affects the distributions of dust, water vapor and water ice, and thus atmospheric heating and cooling and the resulting circulations. We use the NASA Ames Mars GCM to investigate the effects of radiatively active water ice clouds on surface stress and the potential for dust lifting. The model includes a state-of-the-art water ice cloud microphysics package and a radiative transfer scheme that accounts for the radiative effects of CO2 gas, dust, and water ice clouds. We focus on simulations that are radiatively forced by a prescribed dust map, and we compare simulations that do and do not include radiatively active clouds. Preliminary results suggest that the magnitude and spatial patterns of surface stress (and thus dust lifting potential) are substantial influenced by the radiative effects of water ice clouds.

  14. A simple model for yield prediction of rice based on vegetation index derived from satellite and AMeDAS data during ripening period

    International Nuclear Information System (INIS)

    The present study was conducted to show a simple model for rice yield predicting by using a vegetation index (NDVI) derived from satellite and meteorological data. In a field experiment, the relationship between the vegetation index and radiation absorbed by the rice canopy was investigated from transplanting to maturity. Their correlation held. This result revealed that the vegetation index could be used as a measure of absorptance of solar radiation by rice canopy. NDVI multiplied by solar radiation (SR) every day was accumulated (Σ(SR·NDVI)) from the field experiment. Σ(SR·NDVI) was plotted against above ground dry matter. It was obvious that they had a strong relationship. Rice yield largely depends on solar radiation and air temperature during the ripening period. Air temperature affects dry matter production. Relationships between Y SR-1 (Y: rice yield, SR: solar radiation) and mean air temperature were investigated from meteorological data and statistical data on rice yield. There was an optimum air temperature, 21.3°C, for ripening. When it was near 21.3°C in the ripening period, the rice yield was higher. We proposed a simple model for yield prediction of rice based on these results. The model is composed with SR·NDVI and the optimum air temperature. Vegetation index was derived from 3 years, LANDSAT TM data in Toyama, Ishikawa, Fukui and Nagano prefectures at heading. The meteorological data was used from AMeDAS data. The model was described as follows: Y = 0.728 SR·NDVI−2.04(T−21.3)2 + 282 (r2 = 0.65, n = 43) where Y is rice yield (kg 10a-1), SR is solar radiation (MJ m-2) during the ripening period (from 10 days before heading to 30 days after heading), T is mean air temperature (°C) during the ripening period. RMSE was 33.7kg 10a-1. The model revealed good precision. (author)

  15. Field Tested Service Oriented Robotic Architecture: Case Study

    Science.gov (United States)

    Flueckiger, Lorenzo; Utz, Hanz

    2012-01-01

    This paper presents the lessons learned from six years of experiments with planetary rover prototypes running the Service Oriented Robotic Architecture (SORA) developed by the Intelligent Robotics Group (IRG) at NASA Ames Research Center. SORA relies on proven software methods and technologies applied to the robotic world. Based on a Service Oriented Architecture and robust middleware, SORA extends its reach beyond the on-board robot controller and supports the full suite of software tools used during mission scenarios from ground control to remote robotic sites. SORA has been field tested in numerous scenarios of robotic lunar and planetary exploration. The results of these high fidelity experiments are illustrated through concrete examples that have shown the benefits of using SORA as well as its limitations.

  16. Enhanced response of the Salmonella mutagenicity test to ionizing radiations

    International Nuclear Information System (INIS)

    Gamma-ray-induced reversions in the Ames Salmonella tester strain TA2638 have been studied for their dependence on a number of experimental parameters. It is shown that exposure to ionizing radiations soon after plating is not the procedure that yields results which correspond to those obtained in the standard utilization of the test with chemical mutagens. The ability to detect mutants is improved by irradiation 6 hr after the beginning of the incubation of the plated bacteria. This procedure has the double advantage of a markedly increased ratio of radiation-induced to spontaneous revertants and of resulting in substantial insensitivity to fluctuations in the number of bacteria initially plated. The reversion-doubling dose so obtained is 1.3 Gy; i.e., it is sufficiently small to disregard inactivation of the bacteria

  17. Azimuthal Anisotropies as Stringent Test for Nuclear Transport Models

    CERN Document Server

    Crochet, Philippe; Donà, R

    1997-01-01

    Azimuthal distributions of charged particles and intermediate mass fragments emitted in Au+Au collisions at 600AMeV have been measured using the FOPI facility at GSI-Darmstadt. Data show a strong increase of the in-plane azimuthal anisotropy ratio with the charge of the detected fragment. Intermediate mass fragments are found to exhibit a strong momentum-space alignment with respect of the reaction plane. The experimental results are presented as a function of the polar center-of-mass angle and over a broad range of impact parameters. They are compared to the predictions of the Isospin Quantum Molecular Dynamics model using three different parametrisations of the equation of state. We show that such highly accurate data provide stringent test for microscopic transport models and can potentially constrain separately the stiffness of the nuclear equation of state and the momentum dependence of the nuclear interaction.

  18. Preclinical test: bacterial reverse mutation test for {sup 18}F-fluorocholine produced in CDTN

    Energy Technology Data Exchange (ETDEWEB)

    Mendes, Bruno M.; Bispo, Ana Carolina A.; Campos, Danielle C.; Silva, Juliana B., E-mail: bmm@cdtn.br, E-mail: acab@cdtn.br, E-mail: dcc@cdtn.br, E-mail: silvajb@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2013-07-01

    The choline labeled with fluorine-18 (18FCH) is being considered as a great importance radiopharmaceutical due to its effective detection of many type of malignant neoplasm. The research related to {sup 18}F-fluorocholine synthesis in CDTN was initiated in 2010. In order to obtain clinical research approval, as well as to register {sup 18}FCH for marketing, safety and efficacy preclinical testing are required. The present work evaluated the {sup 18}FCH genotoxic potential through the bacterial reverse mutation test (Ames test) using Salmonella typhimurium TA-98, TA-100, TA-1535 and TA-1537 strains and Escherichia coli WP2 uvrA strain. The reverse mutation test in bacteria for fluorcolina was conducted in two stages. Initially the method was applied to 'cold' fluorocholine molecule (19FCH). Subsequently, the decayed product of {sup 18}FCH synthesis was evaluated. The first step was performed in order to examine the FCH molecule mutagenicity. The second was carried out to determine the mutagenic potential of final product. All strains were tested in triplicate for each exposure concentration, in the presence and absence of metabolic activation (S-9 mix - 10%). There were no statistically significant increases in revertant colonies rate for any strains tested after their exposure to decayed {sup 18}FCH or {sup 19}FCH. The number of revertant colonies in positive controls was significantly higher than that observed in significant increases in revertant colonies rate for any strains tested after their exposure to decayed {sup 18}FCH or {sup 19}FCH. The number of revertant colonies in positive controls was significantly higher than that observed in negative controls. Based on results of this assay, {sup 18}FCH and {sup 19}FCH, at tested doses, were found to be non-mutagenic in bacterial reverse mutation test. (author)

  19. Preclinical test: bacterial reverse mutation test for 18F-fluorocholine produced in CDTN

    International Nuclear Information System (INIS)

    The choline labeled with fluorine-18 (18FCH) is being considered as a great importance radiopharmaceutical due to its effective detection of many type of malignant neoplasm. The research related to 18F-fluorocholine synthesis in CDTN was initiated in 2010. In order to obtain clinical research approval, as well as to register 18FCH for marketing, safety and efficacy preclinical testing are required. The present work evaluated the 18FCH genotoxic potential through the bacterial reverse mutation test (Ames test) using Salmonella typhimurium TA-98, TA-100, TA-1535 and TA-1537 strains and Escherichia coli WP2 uvrA strain. The reverse mutation test in bacteria for fluorcolina was conducted in two stages. Initially the method was applied to 'cold' fluorocholine molecule (19FCH). Subsequently, the decayed product of 18FCH synthesis was evaluated. The first step was performed in order to examine the FCH molecule mutagenicity. The second was carried out to determine the mutagenic potential of final product. All strains were tested in triplicate for each exposure concentration, in the presence and absence of metabolic activation (S-9 mix - 10%). There were no statistically significant increases in revertant colonies rate for any strains tested after their exposure to decayed 18FCH or 19FCH. The number of revertant colonies in positive controls was significantly higher than that observed in significant increases in revertant colonies rate for any strains tested after their exposure to decayed 18FCH or 19FCH. The number of revertant colonies in positive controls was significantly higher than that observed in negative controls. Based on results of this assay, 18FCH and 19FCH, at tested doses, were found to be non-mutagenic in bacterial reverse mutation test. (author)

  20. Laboratory Tests

    Science.gov (United States)

    Laboratory tests check a sample of your blood, urine, or body tissues. A technician or your doctor ... compare your results to results from previous tests. Laboratory tests are often part of a routine checkup ...

  1. Laboratory Tests

    Science.gov (United States)

    ... Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & ... or conditions. What are lab tests? Laboratory tests are medical procedures that involve testing samples of blood, urine, or other tissues or ...

  2. IQ testing

    Science.gov (United States)

    IQ (intelligence quotient) testing is a series of exams used to determine your general intelligence in relation ... Many IQ tests are used today. Whether they measure actual intelligence or simply certain abilities is controversial. IQ tests ...

  3. Two-Dimensional Finite Element Ablative Thermal Response Analysis of an Arcjet Stagnation Test

    Science.gov (United States)

    Dec, John A.; Laub, Bernard; Braun, Robert D.

    2011-01-01

    The finite element ablation and thermal response (FEAtR, hence forth called FEAR) design and analysis program simulates the one, two, or three-dimensional ablation, internal heat conduction, thermal decomposition, and pyrolysis gas flow of thermal protection system materials. As part of a code validation study, two-dimensional axisymmetric results from FEAR are compared to thermal response data obtained from an arc-jet stagnation test in this paper. The results from FEAR are also compared to the two-dimensional axisymmetric computations from the two-dimensional implicit thermal response and ablation program under the same arcjet conditions. The ablating material being used in this arcjet test is phenolic impregnated carbon ablator with an LI-2200 insulator as backup material. The test is performed at the NASA, Ames Research Center Interaction Heating Facility. Spatially distributed computational fluid dynamics solutions for the flow field around the test article are used for the surface boundary conditions.

  4. Wind Tunnel and Hover Performance Test Results for Multicopter UAS Vehicles

    Science.gov (United States)

    Russell, Carl R.; Jung, Jaewoo; Willink, Gina; Glasner, Brett

    2016-01-01

    There is currently a lack of published data for the performance of multicopter unmanned aircraft system (UAS) vehicles, such as quadcopters and octocopters, often referred to collectively as drones. With the rapidly increasing popularity of multicopter UAS, there is interest in better characterizing the performance of this type of aircraft. By studying the performance of currently available vehicles, it will be possible to develop models for vehicles at this scale that can accurately predict performance and model trajectories. This paper describes a wind tunnel test that was recently performed in the U.S. Army's 7- by 10-ft Wind Tunnel at NASA Ames Research Center. During this wind tunnel entry, five multicopter UAS vehicles were tested to determine forces and moments as well as electrical power as a function of wind speed, rotor speed, and vehicle attitude. The test is described here in detail, and a selection of the key results from the test is presented.

  5. Randomization tests

    CERN Document Server

    Edgington, Eugene

    2007-01-01

    Statistical Tests That Do Not Require Random Sampling Randomization Tests Numerical Examples Randomization Tests and Nonrandom Samples The Prevalence of Nonrandom Samples in Experiments The Irrelevance of Random Samples for the Typical Experiment Generalizing from Nonrandom Samples Intelligibility Respect for the Validity of Randomization Tests Versatility Practicality Precursors of Randomization Tests Other Applications of Permutation Tests Questions and Exercises Notes References Randomized Experiments Unique Benefits of Experiments Experimentation without Mani

  6. Measurement of isotopic cross sections of the fission fragments produced in 500 AMeV {sup 208}Pb + p reaction; Etude de la production des fragments de fission issus de la reaction {sup 208}Pb + p a 500 AMeV

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez-Dominguez, B

    2003-03-01

    The aim of this work is the study of the fission fragments produced in the spallation reaction {sup 208}Pb + p at 500 AMeV. The fission fragments from Z=23 up to Z=59 have been detected and identified by using the inverse kinematics technique with the high-resolution spectrometer FRS. The production cross sections and the recoil velocities of 430 nuclei have been measured. The measured data have been compared with previous data. The isotopic distributions show a high precision. However, the absolute value of the fission cross section is higher than expected. From the experimental data the characteristics of the average fissioning system have been reconstructed (Z{sub fis}, A{sub fis}, E*{sub fis}). In addition, the number of post-fission neutrons emitted from the fission fragments, v{sub post}, has been determined by using a new method. The experimental data have been compared to the two-steps models describing the spallation reaction. The impact of the model parameters on the observables has been analysed and the reasons Leading to the observed differences between the codes are also presented. This analyse shows a good agreement with the INCL4+ABLA code. (author)

  7. Analysis and characterization of heavy residues produced in {sup 129}Xe + {sup nat}Sn reactions between 8 and 25 AMeV; Analyse et caracterisation des residus lourds produits dans les reactions {sup 129}Xe + {sup nat}Sn entre 8 et 25 AMeV

    Energy Technology Data Exchange (ETDEWEB)

    Moisan, J

    2008-06-15

    Studies with the INDRA multidetector of the {sup 129}Xe + {sup nat}Sn reactions showed the unexpected existence of heavy fragments with a charge as large as Z=70. The charges of Xe and Sn are 54 and 50 respectively. Reactions between nuclei with a charge product greater than 2700 are dominated by deep inelastic collisions. For Xe + Sn the product is exactly 2700. After these observations, {sup 129}Xe + {sup nat}Sn reactions at 8, 12, 15, 20 and 25 AMeV have been done. It will then be possible to clarify if the heavy residues are formed by an incomplete fusion, massive transfers occurring in deep inelastic collisions or a very asymmetric fission of a compound system. This work will present experimental results obtained by the analysis of these experiments. We will show that heavy residues are formed with a production cross-section of 10{sup -2} mb. Angular distributions show that the residues can be produced by an incomplete fusion of the projectile and the target. The study of the products in coincidence with the residues shows that a compound system was formed, followed by a fission producing the residue and a lighter fragment. The comparison with a phenomenological model, HIPSE, confirms that the model is valid at these energies.

  8. Performance tests.

    OpenAIRE

    Wetherell, A

    1996-01-01

    This paper discusses the use of psychological performance tests to assess the effects of environmental stressors. The large number and the variety of performance tests are illustrated, and the differences between performance tests and other psychological tests are described in terms of their design, construction, use, and purpose. The stressor emphasis is on the effects of drugs since that is where most performance tests have found their main application, although other stressors, e.g., fatig...

  9. Biological Visualization, Imaging and Simulation(Bio-VIS) at NASA Ames Research Center: Developing New Software and Technology for Astronaut Training and Biology Research in Space

    Science.gov (United States)

    Smith, Jeffrey

    2003-01-01

    The Bio- Visualization, Imaging and Simulation (BioVIS) Technology Center at NASA's Ames Research Center is dedicated to developing and applying advanced visualization, computation and simulation technologies to support NASA Space Life Sciences research and the objectives of the Fundamental Biology Program. Research ranges from high resolution 3D cell imaging and structure analysis, virtual environment simulation of fine sensory-motor tasks, computational neuroscience and biophysics to biomedical/clinical applications. Computer simulation research focuses on the development of advanced computational tools for astronaut training and education. Virtual Reality (VR) and Virtual Environment (VE) simulation systems have become important training tools in many fields from flight simulation to, more recently, surgical simulation. The type and quality of training provided by these computer-based tools ranges widely, but the value of real-time VE computer simulation as a method of preparing individuals for real-world tasks is well established. Astronauts routinely use VE systems for various training tasks, including Space Shuttle landings, robot arm manipulations and extravehicular activities (space walks). Currently, there are no VE systems to train astronauts for basic and applied research experiments which are an important part of many missions. The Virtual Glovebox (VGX) is a prototype VE system for real-time physically-based simulation of the Life Sciences Glovebox where astronauts will perform many complex tasks supporting research experiments aboard the International Space Station. The VGX consists of a physical display system utilizing duel LCD projectors and circular polarization to produce a desktop-sized 3D virtual workspace. Physically-based modeling tools (Arachi Inc.) provide real-time collision detection, rigid body dynamics, physical properties and force-based controls for objects. The human-computer interface consists of two magnetic tracking devices

  10. Tensile testing

    CERN Document Server

    2004-01-01

    A complete guide to the uniaxial tensile test, the cornerstone test for determining the mechanical properties of materials: Learn ways to predict material behavior through tensile testing. Learn how to test metals, alloys, composites, ceramics, and plastics to determine strength, ductility and elastic/plastic deformation. A must for laboratory managers, technicians, materials and design engineers, and students involved with uniaxial tensile testing. Tensile Testing , Second Edition begins with an introduction and overview of the test, with clear explanations of how materials properties are determined from test results. Subsequent sections illustrate how knowledge gained through tensile tests, such as tension properties to predict the behavior (including strength, ductility, elastic or plastic deformation, tensile and yield strengths) have resulted in improvements in materals applications. The Second Edition is completely revised and updated. It includes expanded coverage throughout the volume on a variety of ...

  11. Urine test.

    Science.gov (United States)

    1996-08-23

    On August 6, 1996, the Food and Drug Administration (FDA) approved the first urine test to detect HIV antibodies. The FDA states that the urine test, developed by Calypte Biomedical Corp. of Berkeley, CA, should not be used to screen donors at blood banks and should be used only as a supplemental diagnostic tool because it is not as accurate as the standard blood-based test. The test, for use only by health care professionals and insurance companies, will be marketed by Seradum Inc. of Indianapolis under the trade name Sentinel. The price will be $40 to $50, comparable to the recently approved saliva-based tests. Advocates of the urine test say it is safer, easier, and less intrusive than blood testing. Critics say the tests are too unreliable and fear that the urine samples used in drug testing in the workplace also could be used to screen out HIV-positive job applicants. PMID:11363733

  12. Objective Tests versus Subjective tests

    Institute of Scientific and Technical Information of China (English)

    魏福林

    2007-01-01

    objective test has only one correct answer, while subjective test has a range of possible answers. Because of this feature, reliability will not be difficult to achieve in the marking of the objective item, while the marking of the subjective items is reliable. On the whole, a good test must contain both subjective and objective test items.

  13. Tests of Full-Scale Helicopter Rotors at High Advancing Tip Mach Numbers and Advance Ratios

    Science.gov (United States)

    Biggers, James C.; McCloud, John L., III; Stroub, Robert H.

    2015-01-01

    As a continuation of the studies of reference 1, three full-scale helicopter rotors have been tested in the Ames Research Center 40- by SO-foot wind tunnel. All three of them were two-bladed, teetering rotors. One of the rotors incorporated the NACA 0012 airfoil section over the entire length of the blade. This rotor was tested at advance ratios up to 1.05. Both of the other rotors were tapered in thickness and incorporated leading-edge camber over the outer 20 percent of the blade radius. The larger of these rotors was tested at advancing tip Mach numbers up to 1.02. Data were obtained for a wide range of lift and propulsive force, and are presented without discussion.

  14. Testing of a Wireless Sensor System for Instrumented Thermal Protection Systems

    Science.gov (United States)

    Kummer, Allen T.; Weir, Erik D.; Morris, Trey J.; Friedenberger, Corey W.; Singh, Aseem; Capuro, Robert M.; Bilen, Sven G.; Fu, Johnny; Swanson, Gregory T.; Hash, David B.

    2011-01-01

    Funded by NASA's Constellation Universities Institutes Project (CUIP), we have been developing and testing a system to wirelessly power and collect data from sensors on space platforms in general and, in particular, the harsh environment of spacecraft re-entry. The elimination of wires and associated failures such as chafing, sparking, ageing, and connector issues can increase reliability and design flexibility while reducing costs. These factors present an appealing case for the pursuit of wireless solutions for harsh environments, particularly for their use in space and on spacecraft. We have designed and built a prototype wireless sensor system. The system, with capabilities similar to that of a wired sensor system, was tested in NASA Ames Research Center s Aerodynamic Heating Facility and Interaction Heating Facility. This paper discusses the overall development effort, testing results, as well as future directions.

  15. UHTC Research at NASA Ames

    Science.gov (United States)

    Johnson, Sylvia M.

    2011-01-01

    For enhanced aerodynamic performance. Materials for sharp leading edges can be reusable but need different properties because of geometry and very high temperatures. Require materials with significantly higher temperature capabilities, but for short duration. Current shuttle RCC leading edge materials: T approx. 1650 C. Materials for vehicles with sharp leading edges: T>2000 C. >% Figure depicts: High Temperature at Tip and Steep Temperature Gradient. Passive cooling is simplest option to manage the intense heating on sharp leading edges.

  16. Test quality

    International Nuclear Information System (INIS)

    This document discusses inservice testing of safety-related components at nuclear power plants which is performed under the American Society of Mechanical Engineers Boiler and Pressure Vessel Code (the Code). Subsections IWP and IWV of Section XI of the Code state test method and frequency requirements for pumps and valves respectively. Tests vary greatly in quality and frequency. This paper explores the concept of test quality and its relationship with operational readiness and preventive maintenance. This paper also considers the frequencies of component testing. Test quality is related to a test's ability to detect degradation that can cause component failure. The quality of the test depends on several factors, including specific parameters measured, system or component conditions, and instrument accuracy. The quality of some currently required tests for check valves, motor-operated valves, and pumps is also discussed. Suggestions are made to improve test quality by measuring different parameters, testing valves under load, and testing positive displacement pumps at high pressure and centrifugal pumps at high flow rate conditions. These suggestions can help to improve the level of assurance of component operational readiness gained from testing

  17. Predictive Testing

    Science.gov (United States)

    ... is used to check for mutations linked to Huntington’s Disease. Predispositional Testing: Positive tests results show that you ... results. Twitter YouTube RSS Genetics and Health How Genes Work Genes, Lifestyle, & Environment Collecting Family Health History ...

  18. Triglycerides Test

    Science.gov (United States)

    ... Cholesterol ; LDL Cholesterol ; Direct LDL Cholesterol ; VLDL Cholesterol ; Lipid Profile ; Cardiac Risk Assessment All content on Lab Tests ... tests for triglycerides are usually part of a lipid profile used to identify the risk of developing heart ...

  19. Glucose Tests

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Glucose Tests Share this page: Was this page helpful? ... the meaning of other test results. Fasting Blood Glucose Glucose Level Indication From 70 to 99 mg/ ...

  20. TSH test

    Science.gov (United States)

    ... different samples. Talk to your provider about the meaning of your specific test results. If you are ... iodine in the body (due to receiving iodine contrast used during imaging tests, such as CT scan) ...

  1. Genetic Testing

    Science.gov (United States)

    ... a photograph.) These are important tests because they characterize the extent to which the immune system is ... by males as well as females. Therefore, one person’s gene test doesn’t necessarily mean that the ...

  2. Nationale test

    DEFF Research Database (Denmark)

    2009-01-01

    Professor Sven Erik Nordenbo og centerleder Niels Egelund, begge DPU, i samtale om nationale test.......Professor Sven Erik Nordenbo og centerleder Niels Egelund, begge DPU, i samtale om nationale test....

  3. Toxoplasmosis Testing

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Toxoplasmosis Testing Share this page: Was this page helpful? ... I should know? How is it used? A toxoplasmosis test is used to detect a current or ...

  4. Ferritin Test

    Science.gov (United States)

    ... page: Was this page helpful? Also known as: Serum Ferritin Formal name: Ferritin, serum Related tests: Complete Blood Count , Hemoglobin , Hematocrit , Serum Iron , TIBC, UIBC and Transferrin , Iron Tests , Zinc Protoporphyrin , ...

  5. Nationale Test

    DEFF Research Database (Denmark)

    2009-01-01

    Hvad er egentlig formålet med de nationale test? Bliver eleverne klogere af at blive testet? Og er der en sammenhæng mellem bandekrig og nationale test? Fysisk medie: dpu.dk/tv......Hvad er egentlig formålet med de nationale test? Bliver eleverne klogere af at blive testet? Og er der en sammenhæng mellem bandekrig og nationale test? Fysisk medie: dpu.dk/tv...

  6. HIV Testing

    Science.gov (United States)

    ... Abroad Treatment Basic Statistics Get Tested Find an HIV testing site near you. Enter ZIP code or city Follow HIV/AIDS CDC HIV CDC HIV/AIDS See RSS | ... All Collapse All Should I get tested for HIV? CDC recommends that everyone between the ages of ...

  7. Schilling test

    Science.gov (United States)

    Vitamin B12 absorption test ... This test may be done in four different stages to find the cause of a low vitamin B12 level. ... can absorb vitamin B12. Stage II of the test can tell whether a low vitamin B12 level ...

  8. Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol

    International Nuclear Information System (INIS)

    The Salmonella/microsome test developed by Ames and his coworkers has been widely used in the evaluation of chemicals for genotoxic potential. Although the value of this assay is well recognized, there have been no comprehensive studies on the interlaboratory reproducibility of the method using a standardized protocol. A program was therefore initiated to compare the results obtained in four laboratories from testing a series of coded mutagens and nonmutagens using a standardized protocol. Additional objectives of this study were to compare male Fisher 344 rat, B6C3F1 mouse, and Syrian hamster liver S-9 preparations for the activation of chemicals; to compare Aroclor 1254-induced liver S-9 from all three species with the corresponding non-induced liver S-9's; and to compare the response of Escherichia coli WP-2 uvrA with the Salmonella typhimurium tester strains recommended by Ames. Since a primary use of in vitro microbial mutagenesis tests is the identification of potential carcinogens by their mutagenicity, the authors decided to compare the animal species and strains used by the National Cancer Institute/National Toxicology Program (NCI/NTP) for animal carcinogenicity studies

  9. Analytical testing

    Science.gov (United States)

    Flannelly, W. G.; Fabunmi, J. A.; Nagy, E. J.

    1981-01-01

    Analytical methods for combining flight acceleration and strain data with shake test mobility data to predict the effects of structural changes on flight vibrations and strains are presented. This integration of structural dynamic analysis with flight performance is referred to as analytical testing. The objective of this methodology is to analytically estimate the results of flight testing contemplated structural changes with minimum flying and change trials. The category of changes to the aircraft includes mass, stiffness, absorbers, isolators, and active suppressors. Examples of applying the analytical testing methodology using flight test and shake test data measured on an AH-1G helicopter are included. The techniques and procedures for vibration testing and modal analysis are also described.

  10. Use of Geomatic Techniques to Evaluate Flooding from the February, 1998 Extreme Storm and Sea Level Rise at NASA Ames Research Center

    Science.gov (United States)

    Kirkendall, W. G.; Mills, W. B.; Roy, S.; Costa-Cabral, M.; Milesi, C.

    2013-12-01

    NASA Ames Research Center (ARC), located on the San Francisco Bay, is highly vulnerable to flooding, and to sea level rise (SLR). This fact was driven home in the winter of 1998 when, in combination with a sea level 50 cm higher than the previous neap tide, the February Extreme Storm inundated ARC with over 8 cm of rain in a 24 hour period. In total 26 cm of rain fell during the month of February, with 14 cm during the period of the Extreme Storm from February 3rd to February 9th. The ARC campus and surrounding areas were severely flooded leading to significant damage to the local infrastructure. To assess the potential impact of future storm events to the ARC campus, the February 1998 Extreme Storm was evaluated using several remote sensing and geomatic techniques. Supervised classification and change detection of multispectral Landsat 5 (TM) imagery from January 17 and February 18, 1998 was performed in order to evaluate the extent of flooding after the storm. Both images were recorded at low tide with water levels less than the MLLW value when referenced to the tidal station datum. Significantly more area is classified as water in the February image than in the January image. However, change detection analysis underestimates total flood water coverage due to the lag between the end of the Extreme storm and the available Landsat scene epoch. Ground classification of a publicly available Light Detection and Ranging (LiDAR) point cloud was performed, and a high resolution 1-m digital elevation model (DEM) of the ARC campus was generated and hydro-flattened to provide a topographic reference for geospatial analysis. Feature extraction of buildings from the LiDAR point cloud was performed to provide a high resolution 3D model of the ARC campus. The LiDAR DEM was incorporated into FEMA's natural hazard risk assessment and loss estimation software package Hazus-MH 2.1 to generate a flood depth grid. This flood depth grid estimates the extent of flooding due to the

  11. Trace test

    OpenAIRE

    Leykin, Anton; Sottile, Frank

    2016-01-01

    We give a brief derivation of the trace test to verify completeness of a partial witness set of an irreducible variety in affine or projective space. We then consider the trace test for subvarieties of products of projective spaces working with multihomogeneous witness sets. We show how a dimension reduction based on Bertini's Theorem leads to a practical trace test in this case involving a curve in a small-dimensional affine space.

  12. Testing Interfaces

    DEFF Research Database (Denmark)

    Holbøll, Joachim T.; Henriksen, Mogens; Nilson, Jesper K.;

    1999-01-01

    the insulation and eventually cause breakdown.It is difficult to make a model of the real-life components that can be used to examine all of these phenomena. Some decisions have to be made on how to approach this problem, how to design a test cell and how the tests should be carried out. In this paper......, four suggestions on test cells are considered....

  13. Testing Interfaces

    DEFF Research Database (Denmark)

    Holbøll, Joachim T.; Henriksen, Mogens; Nilson, Jesper K.;

    1999-01-01

    , destroy the insulation and eventually cause breakdown. It is difficult to make a model of the real-life components that can be used to examine all of these phenomena. Some decisions have to be made on how to approach this problem, how to design a test cell and how the tests should be carried out. In this...... paper, four suggestions on test cells are considered....

  14. Software testing

    Science.gov (United States)

    Price-Whelan, Adrian M.

    2016-01-01

    Now more than ever, scientific results are dependent on sophisticated software and analysis. Why should we trust code written by others? How do you ensure your own code produces sensible results? How do you make sure it continues to do so as you update, modify, and add functionality? Software testing is an integral part of code validation and writing tests should be a requirement for any software project. I will talk about Python-based tools that make managing and running tests much easier and explore some statistics for projects hosted on GitHub that contain tests.

  15. Ultrasonic testing

    Energy Technology Data Exchange (ETDEWEB)

    Song, Sung Jin [Sungkwunkwan Univ., Seoul (Korea, Republic of); Jeong, Hyun Jo [Wonkwang Univ., Iksan (Korea, Republic of)

    2004-02-15

    For the proper performance of ultrasonic testing of steel welded joints, and anisotropic material it is necessary to have sound understanding on the underlying physics. To provide such an understanding, it is beneficial to have simulation tools for ultrasonic testing. In order to address such a need, we develop effective approaches to simulate angle beam ultrasonic testing with a personal computer. The simulation is performed using ultrasonic measurement models based on the computationally efficient multi-Gaussian beams. This reach will describe the developed ultrasonic testing models together with the experimental verification of their accuracy.

  16. Orion Launch Abort Vehicle Attitude Control Motor Testing

    Science.gov (United States)

    Murphy, Kelly J.; Brauckmann, Gregory J.; Paschal, Keith B.; Chan, David T.; Walker, Eric L.; Foley, Robert; Mayfield, David; Cross, Jared

    2011-01-01

    Current Orion Launch Abort Vehicle (LAV) configurations use an eight-jet, solid-fueled Attitude Control Motor (ACM) to provide required vehicle control for all proposed abort trajectories. Due to the forward position of the ACM on the LAV, it is necessary to assess the effects of jet-interactions (JI) between the various ACM nozzle plumes and the external flow along the outside surfaces of the vehicle. These JI-induced changes in flight control characteristics must be accounted for in developing ACM operations and LAV flight characteristics. A test program to generate jet interaction aerodynamic increment data for multiple LAV configurations was conducted in the NASA Ames and NASA Langley Unitary Plan Wind Tunnels from August 2007 through December 2009. Using cold air as the simulant gas, powered subscale models were used to generate interaction data at subsonic, transonic, and supersonic test conditions. This paper presents an overview of the complete ACM JI experimental test program for Orion LAV configurations, highlighting ACM system modeling, nozzle scaling assumptions, experimental test techniques, and data reduction methodologies. Lessons learned are discussed, and sample jet interaction data are shown. These data, in conjunction with computational predictions, were used to create the ACM JI increments for all relevant flight databases.

  17. Service Oriented Robotic Architecture for Space Robotics: Design, Testing, and Lessons Learned

    Science.gov (United States)

    Fluckiger, Lorenzo Jean Marc E; Utz, Hans Heinrich

    2013-01-01

    This paper presents the lessons learned from six years of experiments with planetary rover prototypes running the Service Oriented Robotic Architecture (SORA) developed by the Intelligent Robotics Group (IRG) at the NASA Ames Research Center. SORA relies on proven software engineering methods and technologies applied to space robotics. Based on a Service Oriented Architecture and robust middleware, SORA encompasses on-board robot control and a full suite of software tools necessary for remotely operated exploration missions. SORA has been eld tested in numerous scenarios of robotic lunar and planetary exploration. The experiments conducted by IRG with SORA exercise a large set of the constraints encountered in space applications: remote robotic assets, ight relevant science instruments, distributed operations, high network latencies and unreliable or intermittent communication links. In this paper, we present the results of these eld tests in regard to the developed architecture, and discuss its bene ts and limitations.

  18. Using information Theory in Optimal Test Point Selection for Health Management in NASA's Exploration Vehicles

    Science.gov (United States)

    Mehr, Ali Farhang; Tumer, Irem

    2005-01-01

    In this paper, we will present a new methodology that measures the "worth" of deploying an additional testing instrument (sensor) in terms of the amount of information that can be retrieved from such measurement. This quantity is obtained using a probabilistic model of RLV's that has been partially developed in the NASA Ames Research Center. A number of correlated attributes are identified and used to obtain the worth of deploying a sensor in a given test point from an information-theoretic viewpoint. Once the information-theoretic worth of sensors is formulated and incorporated into our general model for IHM performance, the problem can be formulated as a constrained optimization problem where reliability and operational safety of the system as a whole is considered. Although this research is conducted specifically for RLV's, the proposed methodology in its generic form can be easily extended to other domains of systems health monitoring.

  19. An investigation of scale model testing of VTOL aircraft in hover

    Science.gov (United States)

    Hill, W. G., Jr.; Jenkins, R. C.; Dudley, M. R.

    1982-01-01

    Utilizing the unique opportunity created by full scale hover testing of the twin-jet Grumman Design 698 VTOL aircraft in the NASA-Ames Hover Facility, a series of experiments was conducted to evaluate the effectivness of scale model testing in predicting full scale behavior. Interference forces were found to be sensitive to aircraft lower surface geometry, but when the geometry was modeled accurately the small scale results matched full scale forces guite well. The interference forces were found to be insensitive to core nozzle temperature and fan nozzle pressure ratio. The results clearly demonstrate that small scale models can be reliably utilized for aircraft and technology development when the appropriate sensitivities are recognized.

  20. TORCH Test

    Science.gov (United States)

    ... Epstein-Barr Virus Antibodies , Chickenpox and Shingles Tests , Parvovirus B19 All content on Lab Tests Online has been ... enterovirus, Epstein-Barr virus , varicella-zoster virus , and parvovirus B19 . ^ Back to top When is it ordered? The ...

  1. Malnutrition Tests

    Science.gov (United States)

    ... indicate possible nutritional deficits, patients may be provided nutritional support prior to a surgery or procedure and be monitored regularly during recovery. Laboratory tests may include: For general screening and ... protein For nutritional status and deficiencies: Iron tests such as serum ...

  2. Proceedings of the international workshop on aged and decommissioned material collection and testing for structural integrity purposes

    International Nuclear Information System (INIS)

    This workshop was sponsored by the CEC DG XI and XII/JRC Petten/AMES and by the Principal Working Group 3 (PWG-3) on reactor component integrity of the NEA CSNI, and it was hosted by the CEN Mol, Belgium. The activities of PWG-3 fall into three main areas: non-destructive examination (NDE), fracture analysis, and ageing/materials degradation. The topic of the workshop falls into the third area of ageing and materials degradation. The titles of the papers are: AMES and other European networks in Integrity of Ageing Structures; Over View of Proving Test on the Reliability of Material of Nuclear Power Plant Components; Activities on Ageing Degradation Phenomena of NPP in Korea; Capability of Investigation on Decommissioned Parts from NPPs at the MPA Stuttgart; How Accurately can Surveillance Specimens Reflect the True State of RPV Materials?; Applicability of Design Codes to Aged Materials; Microstructural Investigations of as-Fabricated, Long-Term Thermally Aged and Neutron Irradiated RPV Materials: An Atom Probe Study; Proposed Post-Service Investigations on Decommissioned Greifswald Units; Tools and Experience in Post Irradiation Examination of Structural Core Components at PSI Hot laboratory; Testing of Beznau NPP Unit 1 Steam Generator Cast Stainless Steel Elbows; Mechanical Properties Characterisation of Irradiated Materials From Operating or Decommissioned Nuclear Power Plants; Long Term Ageing of Cast Ti-Stabilised Stainless Steel; Enhanced Surveillance of Nuclear Reactor Pressure Vessels. Discussions and conclusions are also presented

  3. SMART Rotor Development and Wind-Tunnel Test

    Science.gov (United States)

    Lau, Benton H.; Straub, Friedrich; Anand, V. R.; Birchette, Terry

    2009-01-01

    Boeing and a team from Air Force, NASA, Army, Massachusetts Institute of Technology, University of California at Los Angeles, and University of Maryland have successfully completed a wind-tunnel test of the smart material actuated rotor technology (SMART) rotor in the 40- by 80-foot wind-tunnel of the National Full-Scale Aerodynamic Complex at NASA Ames Research Center, figure 1. The SMART rotor is a full-scale, five-bladed bearingless MD 900 helicopter rotor modified with a piezoelectric-actuated trailing-edge flap on each blade. The development effort included design, fabrication, and component testing of the rotor blades, the trailing-edge flaps, the piezoelectric actuators, the switching power amplifiers, the actuator control system, and the data/power system. Development of the smart rotor culminated in a whirl-tower hover test which demonstrated the functionality, robustness, and required authority of the active flap system. The eleven-week wind tunnel test program evaluated the forward flight characteristics of the active-flap rotor, gathered data to validate state-of-the-art codes for rotor noise analysis, and quantified the effects of open- and closed-loop active-flap control on rotor loads, noise, and performance. The test demonstrated on-blade smart material control of flaps on a full-scale rotor for the first time in a wind tunnel. The effectiveness and the reliability of the flap actuation system were successfully demonstrated in more than 60 hours of wind-tunnel testing. The data acquired and lessons learned will be instrumental in maturing this technology and transitioning it into production. The development effort, test hardware, wind-tunnel test program, and test results will be presented in the full paper.

  4. Analyse et caractérisation des résidus lourds produits dans les réactions $^{129}$Xe + $^{nat}$Sn entre 8 et 25 AMeV

    OpenAIRE

    Moisan, Josiane

    2008-01-01

    Des données obtenues avec le multidétecteur INDRA portant sur des réactions $^{129}$Xe + $^{nat}Sn à 25 AMeV ont montré la présence inattendue de fragments ayant une charge largement supérieure (autour de Z=70) à celles du projectile ou de la cible, qui sont de Z=54 et Z=50 respectivement. Les collisions impliquant des noyaux dont le produit des charges est supérieur à 2700 sont dominées par les transferts très inélastiques. Pour Xe+Sn, ce produit est 2700. Suite à ces observations, une série...

  5. Décroissance de noyaux excités produits dans les réactions 78,82Kr+40Ca à 5.5 AMeV

    OpenAIRE

    Ademard, Guilain

    2011-01-01

    Dans ce travail, nous étudions la désexcitation des noyaux formés dans les réactions 78,82Kr+40Ca à 5,5 AMeV. Le détecteur INDRA est utilisé pour mesurer les particules légères, les résidus d'évaporation et les fragments de numéro atomique 3 ≤ Z ≥ 28.Pour les deux réactions, les caractéristiques des fragments sont compatibles avec un processus de fission. Des oscillations dans les sections efficaces des fragments légers (6 ≤ Z ≥ 11) signalent la persistance d'effets de structure. L'amplitude ...

  6. Influence of the N/Z degree of freedom on the decay modes of excited nuclear complex formed in Kr+Ca reactions at 5.5 AMeV

    International Nuclear Information System (INIS)

    The N/Z degree of freedom is expected to play a crucial role in the decay modes of excited nuclei and in the competition between strongly dissipative and fusion mechanisms. In this contribution we present results obtained in 78,82Kr+40Ca reactions at 5.5 AMeV using the INDRA detector at GANIL. Discussion will be dedicated to various characteristics of the production of light fragments as for example, kinetic energy distributions, odd-even staggering of the cross-sections and excitation energy stored in fragments. These observables seem to reflect the interplay between the N/Z and angular momentum degrees of freedom at the separation phase. The set of data provides some hints for further explorations in the context of reaction with neutron rich projectile to be delivered in a near future. (author)

  7. Análisis Físico-Químico y Morfológico de Almidones de Ñame, Yuca y Papa y Determinación de la Viscosidad de las Pastas Physicochemical and Morphological Analyses of Yam, Cassava and Potato Starches and Determination of their Viscosity

    Directory of Open Access Journals (Sweden)

    Armando Alvis

    2008-01-01

    Full Text Available Se estudiaron las propiedades fisicoquímicas y la morfología y los viscoamilogramas de cuatro almidones nativos de ñame, tres de yuca y uno de papa, Previo a las determinaciones, las muestras fueron secadas hasta peso constante. El contenido de cenizas y amilosa, la temperatura de gelatinización y la viscosidad fue inferior en yuca; la grasa mostró diferencias entre yuca y papa; el índice de absorción de agua en ñame, papa y yuca, mostró diferencias significativas. En el índice de solubilidad en agua no se apreciaron diferencias significativas entre ñame y papa. La facilidad de cocción fue similar en ñame y papa; el incremento en la viscosidad de la pasta fue mayor en ñame y papa. Igualmente, se observaron diferencias en la forma y tamaño del gránulo. Estos cambios en las propiedades, la viscosidad y la morfología, pueden influir en la fabricación y producción de productos alimentarios y no alimentarios derivados de estos almidones.The physicochemical properties, morphology and the viscoamilogrames of yam, potato and cassava native starches were studied. Previous the determinations, the samples were dried up to constant weight. Ash and amylose content, gelatinization temperature and viscosity were lower in cassava; fat showed differences between cassava and potato; water absorption index in yam, potato and cassava showed significant differences. Cooking facility was similar in yam and potato; the increase in paste viscosity was greater in yam and potato. Also, it was observed differences in shape and size granule. These changes in properties, viscosity and morphology can influence the manufacture of food and non-food products derived from these starches.

  8. Penetration testing

    OpenAIRE

    Zemaníková, Martina

    2010-01-01

    This work focuses on the practical demonstration of design penetration testing. Testing is carried out based on the order of a particular entity/subject which is at their request anonymous. The work is divided into two parts, theoretical and practical. We will be made in first part familiarize with the process and techniques of testing, as is now used in ethical hacking, then we can find in the end appropriate recommendations 6 how to prevent and fight against it in order to protect the...

  9. Oedometer Tests

    DEFF Research Database (Denmark)

    Thorsen, Grete

    1996-01-01

    The paper describes the results of oedometer tests carried out with samples from Eemian fresh-water deposits and the methods used to determine the preconsolidation pressure from the test results. The influence of creep in the material on the apparent preconsolidation pressure is estimated from a...... model set up by Moust Jacobsen in 1992. The test results do not show any significant difference in the determined values of the overconsolidation ratio (OCR) for the samples from Hollerup and Solsø, east and west of the main stationary line for the last ice sheet in Weichselian, respectively. The...

  10. AME survey-003 A2: on the attractiveness of an medicine career in current China with a survey of 7,508 medical professionals and 443 non-medical professionals.

    Science.gov (United States)

    Wáng, Yì Xiáng J; Li, Yáo T

    2016-02-01

    This is a part of the study of AME survey-003, aiming to understand the motivation and attractiveness of a career in medicine in China. The surveys were conducted on DXY platform with 3,564 medical professionals during October 26 to November 20; on Sojump platform with 1,587 medical professionals during October 28 to December 14, and 443 non-medical professionals during November 15 to December, all in 2015. Similar to our previous result, the not regretted participants vs. regretted participants (N/Y) ratio was 1.1 (Pmarket to qualified foreign medical organizations to take part in fair competition, as well as favor the government to support regulated private hospitals. Pooled data of 7,508 medical professionals with data from AME survey-003 A1 included showed medicine was the top career choice among medical professionals' children (104/508, 20.5%), followed by finance and economics (74/508, 14.4%), and then electronic engineering or computer science (67/508, 13.2%). Among the 443 non-medical professionals, 122 have children who are attending university or have graduated, 12 (9.8%, 12/122) of them are pursuing a career in medicine. For the 100 non-medical professional parents whose children did not study medicine and if a choice could be given to them to start again, 60 parents (54.5%) replied they would support their children to study medicine. Our results consistently show medicine remained an attractive profession in China. PMID:26981459

  11. Resource Prospector Propulsion System Cold Flow Testing

    Science.gov (United States)

    Williams, Hunter; Holt, Kim; Addona, Brad; Trinh, Huu

    2015-01-01

    Resource Prospector (RP) is a NASA mission being led by NASA Ames Research Center with current plans to deliver a scientific payload package aboard a rover to the lunar surface. As part of an early risk reduction activity, Marshall Space Flight Center (MSFC) and Johnson Space Flight Center (JSC) have jointly developed a government-version concept of a lunar lander for the mission. The spacecraft consists of two parts, the lander and the rover which carries the scientific instruments. The lander holds the rover during launch, cruise, and landing on the surface. Following terminal descent and landing the lander portion of the spacecraft become dormant after the rover embarks on the science mission. The lander will be equipped with a propulsion system for lunar descent and landing, as well as trajectory correction and attitude control maneuvers during transit to the moon. Hypergolic propellants monomethyl hydrazine and nitrogen tetroxide will be used to fuel sixteen 70-lbf descent thrusters and twelve 5-lbf attitude control thrusters. A total of four metal-diaphragm tanks, two per propellant, will be used along with a high-pressure composite-overwrapped pressure vessel for the helium pressurant gas. Many of the major propulsion system components are heritage missile hardware obtained by NASA from the Air Force. In parallel with the flight system design activities, a simulated propulsion system based on flight drawings was built for conducting a series of water flow tests to characterize the transient fluid flow of the propulsion system feed lines and to verify the critical operation modes such as system priming, waterhammer, and crucial mission duty cycles. The primary objective of the cold flow testing was to simulate the RP propulsion system fluid flow operation through water flow testing and to obtain data for anchoring analytical models. The models will be used to predict the transient and steady state flow behaviors in the actual flight operations. All design and

  12. PTT Test

    Science.gov (United States)

    ... when the person has a clinical history of bleeding, such as frequent or excessive nose bleeds and easy bruising, which may indicate the presence of a bleeding disorder ^ Back to top What does the test ...

  13. Fungal Tests

    Science.gov (United States)

    ... or Calcofluor white stain): in general, if fungal elements are seen, then a fungus is the likely the cause of symptoms. These tests, however, do not identify the fungus. Culture: care must be taken when interpreting culture results. ...

  14. Amylase Test

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Amylase Share this page: Was this page helpful? Also known as: Amy Formal name: Amylase Related tests: Lipase , Trypsin , Trypsinogen At a Glance ...

  15. Mono Test

    Science.gov (United States)

    ... white blood cells and reactive lymphocytes on a blood smear in the presence of symptoms associated with mono indicates a likely diagnosis of infectious mononucleosis. A negative mono test requires ...

  16. Sodium Test

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Sodium Share this page: Was this page helpful? Also known as: Na Formal name: Sodium Related tests: Chloride , Bicarbonate , Potassium , Electrolytes , Osmolality , Basic ...

  17. Bilirubin Test

    Science.gov (United States)

    ... Bilirubin; Indirect Bilirubin; Unconjugated Bilirubin Formal name: Bilirubin - blood Related tests: Liver Panel ; GGT ; ALP ; AST ; ALT ; Hepatitis A ; Hepatitis B ; Hepatitis C ; Complete Blood Count ; Urinalysis ; Direct Antiglobulin ...

  18. Insulin Test

    Science.gov (United States)

    ... especially as a result of taking non-human (animal or synthetic) insulin, these can interfere with insulin testing. In this case, a C-peptide may be performed as an alternative way to evaluate insulin production. Note also that ...

  19. Copper Test

    Science.gov (United States)

    ... mean? Copper test results must be evaluated in context and are usually compared to ceruloplasmin levels . Abnormal ... Health Professionals ©2001 - by American Association for Clinical Chemistry • Contact Us | Terms of Use | Privacy We comply ...

  20. Knowledge Test

    DEFF Research Database (Denmark)

    Sørensen, Ole Henning

    1998-01-01

    The knowledge test is about competing temporal and spatial expressions of the politics of technological development and national prosperity in contemporary society. The discussion is based on literature of national systems of innovation and industrial networks of various sorts. Similarities...

  1. Trypsinogen test

    Science.gov (United States)

    ... is broken) Considerations Other tests used to detect pancreas diseases may include: Serum amylase Serum lipase Alternative Names ... Related MedlinePlus Health Topics Cystic Fibrosis Pancreatic Cancer Pancreatic Diseases Browse the Encyclopedia A.D.A.M., Inc. ...

  2. Lipase test

    Science.gov (United States)

    ... the bowel (bowel obstruction) Celiac disease Duodenal ulcer Cancer of the pancreas Infection or swelling of the pancreas This test may also be done for familial lipoprotein lipase deficiency . Risks ... Update Date 2/4/2015 Updated ...

  3. Lipase Test

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Lipase Share this page: Was this page helpful? Also known as: LPS Formal name: Lipase Related tests: Amylase , Trypsin , Trypsinogen At a Glance ...

  4. HPV Test

    Science.gov (United States)

    ... type of HPV infection may benefit from the protection against other types included in the vaccine. ^ Back ... infection. These include having many children, long-term oral contraceptive ... having multiple sex partners, infrequent Pap tests , smoking, a history of ...

  5. Albumin Test

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Albumin Share this page: Was this page helpful? Also known as: ALB Formal name: Albumin, serum Related tests: Liver Panel , Comprehensive Metabolic Panel , ...

  6. VDRL test

    Science.gov (United States)

    ... syphilis . The bacteria that cause syphilis is called Treponema pallidum. Your health care provider may order this test ... 59. Radolf JD, Tramont EC, Salazar JC. Syphilis ( Treponema pallidum ). In: Bennett JE, Dolin R, Blaser MJ, eds. ...

  7. Magnesium Test

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Magnesium Share this page: Was this page helpful? Also known as: Mg; Mag Formal name: Magnesium Related tests: Calcium , Potassium , Phosphorus , PTH , Vitamin D ...

  8. 3-D Printed Ultem 9085 Testing and Analysis

    Science.gov (United States)

    Aguilar, Daniel; Christensen, Sean; Fox, Emmet J.

    2015-01-01

    The purpose of this document is to analyze the mechanical properties of 3-D printed Ultem 9085. This document will focus on the capabilities, limitations, and complexities of 3D printing in general, and explain the methods by which this material is tested. Because 3-D printing is a relatively new process that offers an innovative means to produce hardware, it is important that the aerospace community understands its current advantages and limitations, so that future endeavors involving 3-D printing may be completely safe. This document encompasses three main sections: a Slosh damage assessment, a destructive test of 3-D printed Ultem 9085 samples, and a test to verify simulation for the 3-D printed SDP (SPHERES Docking Port). Described below, 'Slosh' and 'SDP' refer to two experiments that are built using Ultem 9085 for use with the SPHERES (Synchronized Position Hold, Engage, Reorient, Experimental Satellites) program onboard the International Space Station (ISS) [16]. The SPHERES Facility is managed out of the National Aeronautics and Space Administration (NASA) Ames Research Center in California.

  9. Hardware Design and Testing of SUPERball, A Modular Tensegrity Robot

    Science.gov (United States)

    Sabelhaus, Andrew P.; Bruce, Jonathan; Caluwaerts, Ken; Chen, Yangxin; Lu, Dizhou; Liu, Yuejia; Agogino, Adrian K.; SunSpiral, Vytas; Agogino, Alice M.

    2014-01-01

    We are developing a system of modular, autonomous "tensegrity end-caps" to enable the rapid exploration of untethered tensegrity robot morphologies and functions. By adopting a self-contained modular approach, different end-caps with various capabilities (such as peak torques, or motor speeds), can be easily combined into new tensegrity robots composed of rods, cables, and actuators of different scale (such as in length, mass, peak loads, etc). As a first step in developing this concept, we are in the process of designing and testing the end-caps for SUPERball (Spherical Underactuated Planetary Exploration Robot), a project at the Dynamic Tensegrity Robotics Lab (DTRL) within NASA Ames's Intelligent Robotics Group. This work discusses the evolving design concepts and test results that have gone into the structural, mechanical, and sensing aspects of SUPERball. This representative tensegrity end-cap design supports robust and repeatable untethered mobility tests of the SUPERball, while providing high force, high displacement actuation, with a low-friction, compliant cabling system.

  10. Use of genotoxicity tests in a TIE to identify chemicals potentially affecting human health

    International Nuclear Information System (INIS)

    Imperial Oil operates a sour gas processing plant in southern Alberta that has, for the past several years, been the focus of considerable public and regulatory concern over perceived contamination of soils and groundwater on a nearby ranch. Elevated concentrations of DOC (∼140 mg/L) have been received in groundwater underlying the plant site. Two process-related chemicals, sulfolane and diisopropanolamine (DIPA), had been previously identified as the primary components of the DOC plume, although the chemicals associated with 30% of the DOC could not be identified. A risk assessment was initiated in 1994 to determine whether off-site migration of sulfolane and DIPA or of other unidentified contaminants poses a risks to human health and/or ecological receptors. One component of the risk assessment included conducting a TIE to help identify the chemical(s) in contaminated groundwater underlying the gas plant that might adversely affect human health. Three endpoints were utilized in the TIE: MicroTox, SOS-Chromotest and the Ames test. MicroTox was used since it exhibited a response to whole groundwater from the site, while the genotoxicity tests were used because DIPA reportedly causes a response in the Ames test and because of the concern over potential human health affects arising from other unidentified contaminants. Results of the TIE indicated that the chemicals causing the toxicity in the groundwater sample were water soluble compounds, with similar characteristics to the process chemicals used at the gas plant and detected at high concentrations in groundwater from the plant site. These results provided additional evidence to help focus the risk assessment on the chemicals sulfolane and diisopropanolamine

  11. Adaptive test

    DEFF Research Database (Denmark)

    Kjeldsen, Lars Peter; Eriksen, Mette Rose

    2010-01-01

    Artikelen er en evaluering af de adaptive tests, som blev indført i folkeskolen. Artiklen sætter særligt fokus på evaluering i folkeskolen, herunder bidrager den med vejledning til evaluering, evalueringsværktøjer og fagspecifkt evalueringsmateriale.......Artikelen er en evaluering af de adaptive tests, som blev indført i folkeskolen. Artiklen sætter særligt fokus på evaluering i folkeskolen, herunder bidrager den med vejledning til evaluering, evalueringsværktøjer og fagspecifkt evalueringsmateriale....

  12. Fair Testing

    OpenAIRE

    Rensink, Arend; Vogler, W

    2005-01-01

    In this paper we present a solution to the long-standing problem of characterising the coarsest liveness-preserving pre-congruence with respect to a full (TCSP-inspired) process algebra. In fact, we present two distinct characterisations, which give rise to the same relation: an operational one based on a De Nicola-Hennessy-like testing modality which we call should-testing, and a denotational one based on a refined notion of failures. One of the distinguishing characteristics of the should-t...

  13. DHEAS Test

    Science.gov (United States)

    ... be ordered, along with other hormone tests, whenever excess (or, more rarely, deficient) androgen production is suspected and/or when a health ... level, in addition to other normal male hormone ( androgen ) levels, likely ... may indicate that excess DHEAS production is causing or contributing to the ...

  14. Diagnostic test

    International Nuclear Information System (INIS)

    A diagnostic test is provided based on competitive binding in which a partition coefficient is established for the substance whose concentration is to be determined and for the radioactive labeled form of the substance between liquid and solid phases. 10 claims

  15. Stress Tests

    International Nuclear Information System (INIS)

    Our Nuclear Facilities have recently operated in a special regime. Since March until December they were scrutinised by a team verifying and drilling all possible scenarios in case of emergency situations, earthquake, floods or long-term power supply loss. Stress tests were the hard job but their findings are already now a great contribution. (author)

  16. Overview of the Space Launch System Ascent Aeroacoustic Environment Test Program

    Science.gov (United States)

    Herron, Andrew J.; Crosby, William A.; Reed, Darren K.

    2016-01-01

    Characterization of accurate flight vehicle unsteady aerodynamics is critical for component and secondary structure vibroacoustic design. The Aerosciences Branch at the National Aeronautics and Space Administration (NASA) Marshall Space Flight Center has conducted a test at the NASA Ames Research Center (ARC) Unitary Plan Wind Tunnels (UPWT) to determine such ascent aeroacoustic environments for the Space Launch System (SLS). Surface static pressure measurements were also collected to aid in determination of local environments for venting, CFD substantiation, and calibration of the flush air data system located on the launch abort system. Additionally, this test supported a NASA Engineering and Safety Center study of alternate booster nose caps. Testing occurred during two test campaigns: August - September 2013 and December 2013 - January 2014. Four primary model configurations were tested for ascent aeroacoustic environment definition. The SLS Block 1 vehicle was represented by a 2.5% full stack model and a 4% truncated model. Preliminary Block 1B payload and manned configurations were also tested, using 2.5% full stack and 4% truncated models respectively. This test utilized the 11 x 11 foot transonic and 9 x 7 foot supersonic tunnel sections at the ARC UPWT to collect data from Mach 0.7 through 2.5 at various total angles of attack. SLS Block 1 design environments were developed primarily using these data. SLS Block 1B preliminary environments have also been prepared using these data. This paper discusses the test and analysis methodology utilized, with a focus on the unsteady data collection and processing.

  17. Putting Tests To The Test

    Institute of Scientific and Technical Information of China (English)

    王丽荣

    2005-01-01

    Tests are usually a big part of a teacher's life. They are part of the ritual of the classroom. Students expect them. Administrators, school boards and legislators require them. They are important to us in our work; we think about them often and have a lot to say about them.

  18. Genotoxicity testing of low-calorie sweeteners: aspartame, acesulfame-K, and saccharin.

    Science.gov (United States)

    Bandyopadhyay, Atrayee; Ghoshal, Sarbani; Mukherjee, Anita

    2008-01-01

    Low-calorie sweeteners are chemicals that offer the sweetness of sugar without the calories. Consumers are increasingly concerned about the quality and safety of many products present in the diet, in particular, the use of low-calorie sweeteners, flavorings, colorings, preservatives, and dietary supplements. In the present study, we evaluated the mutagenicity of the three low-calorie sweeteners in the Ames/Salmonella/microsome test and their genotoxic potential by comet assay in the bone marrow cells of mice. Swiss albino mice, Mus musculus, were orally administered with different concentrations of aspartame (ASP; 7, 14, 28, and 35 mg/kg body weight), acesulfame-K (ASK; 150, 300, and 600 mg/kg body weight), and saccharin (50, 100, and 200 mg/kg body weight) individually. Concurrently negative and positive control sets were maintained. The animals were sacrificed and the bone marrow cells were processed for comet assay. The standard plate-incorporation assay was carried with the three sweeteners in Salmonella typhimurium TA 97a and TA 100 strains both in the absence and presence of the S9 mix. The comet parameters of DNA were increased in the bone marrow cells due to the sweetener-induced DNA strand breaks, as revealed by increased comet-tail extent and percent DNA in the tail. ASK and saccharin were found to induce greater DNA damage than ASP. However, none could act as a potential mutagen in the Ames/Salmonella /microsome test. These findings are important, since they represent a potential health risk associated with the exposure to these agents. PMID:18850355

  19. APPLICATION OF AMES TEST TO DETECT THE MUTAGENICITY OF DRINKING WATER IN LUZHOU CITY%Ames试验在泸州市饮水致突变性检测中的应用

    Institute of Scientific and Technical Information of China (English)

    张青碧; 陈志群; 甘仲霖; 衡正昌; 汤艳

    2003-01-01

    目的:为了检测泸州市饮水氯化消毒副产物的致突变性.方法:采用Ames试验分别对泸州市南郊水厂的水源水、出厂水、末梢管网水的有机浓集物的致突变性进行检测.结果:水源水的有机浓集物的Ames试验呈阴性,出厂水和末梢管网水的有机浓集物的Ames试验呈阳性反应.结论:通过饮水氯化消毒虽然减少了水中致病微生物的作用,但是增加了氯化消毒副产物的致突变性.

  20. 饮用水Ames致突变性与主要有机污染指标的关系%An Investigation of the Relationship Between Ames'Test Mutagenic Effects and Main Organic Pollutants for Drinking Water

    Institute of Scientific and Technical Information of China (English)

    肖贤明; 林耀军; 潘海祥; 刘祖发; 傅家谟

    2002-01-01

    通过对某城市水源水、自来水及经不同组合工艺净化水Ames试验结果与主要有机污染指标的对应关系分析,发现诱发回变指数MA(TA98)主要与总有机碳有关.在此基础上进一步研究了几种常见有机微污染物与MA 的关系.其研究成果对于认识饮用水致突变性,改进饮水深度处理工艺,提高饮水水质均具有指导作用.

  1. Genotoxicity of Air Borne Particulates Assessed by Comet and the Salmonella Mutagenicity Test in Jeddah, Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Waleed Milaat

    2007-09-01

    Full Text Available Fine airborne respirable particulates less than 10 micrometer (PM10 are considered one of the top environmental public health concerns, since they contain polycyclic aromatic hydrocarbons (PAHs which are among the major carcinogenic compounds found in urban air. The objective of this study is to assess the genotoxicity of the ambient PM10 collected at 11 urban sites in Jeddah, Saudi Arabia. The PM10 extractable organic matter (EOM was examined for its genotoxicity by the single cell gel electrophoresis (SCGE comet assay and the Salmonella mutagenicity (Ames test .Gas chromatography-mass spectrometry was used to quantify 16 PAH compounds in four sites. Samples from oil refinery and heavy diesel vehicles traffic sites showed significant DNA damage causing comet in 20-44% of the cells with tail moments ranging from 0.5-2.0 compared to samples from petrol driven cars and residential area, with comet in less than 2% of the cells and tail moments of < 0.02.In the Ames test, polluted sites showed indirect mutagenic response and caused 20-56 rev/ m3, mean while residential and reference sites caused 2-15 rev /m3. The genotoxicity of the EOM in both tests directly correlated with the amount of organic particulate and the PAHs concentrations in the air samples. The PAHs concentrations ranged between 0.83 ng/m3 in industrial and heavy diesel vehicles traffic sites to 0.18 ng /m3 in the residential area. Benzo(ghipyrene was the major PAH components and at one site it represented 65.4 % of the total PAHs. Samples of the oil refinery site were more genotoxic in the SCGE assay than samples from the heavy diesel vehicles traffic site, despite the fact that both sites contain almost similar amount of PAHs. The opposite was true for the mutagenicity in the Ames test. This could be due to the nature of the EOM in both sites. These findings confirm the genotoxic potency of the PM10 organic extracts to which urban populations are exposed.

  2. Nuclear stress test

    Science.gov (United States)

    ... Persantine stress test; Thallium stress test; Stress test - nuclear; Adenosine stress test; Regadenoson stress test; CAD - nuclear stress; Coronary artery disease - nuclear stress; Angina - nuclear ...

  3. Tests for Reproductive Health

    Science.gov (United States)

    ... 888-220-5446 Test HSV (genital herpes) test Pap test (Pap smear) Syphilis test Urinalysis and urine culture Vaginal ... just because you had a pelvic exam or Pap test. A Pap test does not test for ...

  4. Wind tunnel test of a variable-diameter tiltrotor (VDTR) model

    Science.gov (United States)

    Matuska, David; Dale, Allen; Lorber, Peter

    1994-01-01

    This report documents the results from a wind tunnel test of a 1/6th scale Variable Diameter Tiltrotor (VDTR). This test was a joint effort of NASA Ames and Sikorsky Aircraft. The objective was to evaluate the aeroelastic and performance characteristics of the VDTR in conversion, hover, and cruise. The rotor diameter and nacelle angle of the model were remotely changed to represent tiltrotor operating conditions. Data is presented showing the propulsive force required in conversion, blade loads, angle of attack stability and simulated gust response, and hover and cruise performance. This test represents the first wind tunnel test of a variable diameter rotor applied to a tiltrotor concept. The results confirm some of the potential advantages of the VDTR and establish the variable diameter rotor a viable candidate for an advanced tiltrotor. This wind tunnel test successfully demonstrated the feasibility of the Variable Diameter rotor for tilt rotor aircraft. A wide range of test points were taken in hover, conversion, and cruise modes. The concept was shown to have a number of advantages over conventional tiltrotors such as reduced hover downwash with lower disk loading and significantly reduced longitudinal gust response in cruise. In the conversion regime, a high propulsive force was demonstrated for sustained flight with acceptable blade loads. The VDTR demonstrated excellent gust response capabilities. The horizontal gust response correlated well with predictions revealing only half the response to turbulence of the conventional civil tiltrotor.

  5. Ames Infusion Stories for NASA Annual Technology Report: Development of an Ablative 3D Quartz / Cyanate Ester Composite Multi-Functional Material for the Orion Spacecraft Compression Pad

    Science.gov (United States)

    Smith, Brandon; Jan, Darrell Leslie; Venkatapathy, Ethiraj

    2015-01-01

    Vehicles re-entering Earth's atmosphere require protection from the heat of atmospheric friction. The Orion Multi-Purpose Crew Vehicle (MPCV) has more demanding thermal protection system (TPS) requirements than the Low Earth Orbit (LEO) missions, especially in regions where the structural load passes through. The use of 2-dimensional laminate materials along with a metal insert, used in EFT1 flight test for the compression pad region, are deemed adequate but cannot be extended for Lunar return missions.

  6. The strains recommended for use in the bacterial reverse mutation test (OECD guideline 471) can be certified as non-genetically modified organisms.

    Science.gov (United States)

    Sugiyama, Kei-Ichi; Yamada, Masami; Awogi, Takumi; Hakura, Atsushi

    2016-01-01

    The bacterial reverse mutation test, commonly called Ames test, is used worldwide. In Japan, the genetically modified organisms (GMOs) are regulated under the Cartagena Domestic Law, and organisms obtained by self-cloning and/or natural occurrence would be exempted from the law case by case. The strains of Salmonella typhimurium and Escherichia coli recommended for use in the bacterial reverse mutation test (OECD guideline 471), have been considered as non-GMOs because they can be constructed by self-cloning or naturally occurring bacterial strains, or do not disturb the biological diversity. The present article explains the reasons why these tester strains should be classified as non-GMOs. PMID:27350822

  7. APU diaphragm testing. Test plan

    Science.gov (United States)

    Shelley, Richard

    1992-01-01

    Auxiliary Power Unit (APU) fuel (hydrazine) tanks have had to be removed from the Columbia Shuttle (OV-102) because they have been in service for 11 years, which is the limit of their useful life. As part of an effort to determine whether the useful life of the fuel tanks can be extended, examination of the ethylene propylene rubber (EPR) diaphragm and the metal from one of the APU tanks is required. The JSC Propulsion and Power Division has requested White Sands Test Facility (WSTF) to examine the EPR diaphragm thoroughly and the metal casing generally from one tank. The objective is to examine the EPR diaphragm for signs of degradation that may limit the life of its function in the APU propellant tank. The metal casing will also be examined for signs of surface corrosion.

  8. Allergy testing - skin

    Science.gov (United States)

    Patch tests - allergy; Scratch tests - allergy; Skin tests - allergy; RAST test ... There are three common methods of allergy skin testing. The skin prick test involves: Placing a small amount of substances that may be causing your symptoms on the skin, ...

  9. Mononucleosis spot test

    Science.gov (United States)

    Monospot test; Heterophile antibody test; Heterophile agglutination test; Paul-Bunnell test; Forssman antibody test ... The mononucleosis spot test is done when symptoms of mononucleosis are ... Fatigue Fever Large spleen (possibly) Sore throat Tender ...

  10. A1C test

    Science.gov (United States)

    HbA1C test; Glycated hemoglobin test; Glycosylated hemoglobin test; Hemoglobin glycosylated test; Glycohemoglobin test ... have recently eaten does not affect the A1C test, so you do not need to fast to ...

  11. Study of the mutagenic activity of 6 hepatotoxic pharmaceutical drugs in the Salmonella typhimurium microsome test, and the HGPRT and Na+/K+ ATPase system in cultured mammalian cells.

    Science.gov (United States)

    Dayan, J; Deguingand, S; Truzman, C

    1985-07-01

    Several pharmaceutical drugs show strong hepatotoxicity during therapeutic use. We have studied 6 of them: aminophenazone, clofibrate, nifuroxazide, oxamniquine, perhexiline maleate, tienilic acid. Their mutagenicity was assessed in the Ames test on 6 strains of Salmonella typhimurium, and in V79 Chinese hamster lung cells using a rat-hepatocyte-mediated metabolic activation system and the HGPRT and Na+/K+ ATPase assay. Nifuroxazide was positive in the Ames test in two Salmonella strains (TA100, and TA100 Fr1). In the hepatocyte-mediated mammalian V79 cell system, nifuroxazide, clofibrate and aminophenazone were negative; oxamniquine and tienilic acid were positive with and without metabolic activation in tests looking for ouabain and 6-thioguanine resistance. Perhexiline maleate was negative for the direct induction of 6-thioguanine resistance without metabolic activation, and positive after metabolisation mediated by primary rat's hepatocytes. These results suggest the need for some caution in the use of some pharmaceutical drugs because of hepatotoxicity and because 3 out of 6 drugs were shown to be slightly mutagenic in mammalian cells. PMID:2989681

  12. Dryden Test Pilots 1990 - Smolka, Fullerton, Schneider, Dana, Ishmael, Smith, and McMurtry

    Science.gov (United States)

    1990-01-01

    It was a windy afternoon on Rogers Dry Lake as the research pilots of the National Aeronautics and Space Administration's Ames-Dryden Flight Research Facility gathered for a photo shoot. It was a special day too, the 30th anniversary of the first F-104 flight by research pilot Bill Dana. To celebrate, a fly over of Building 4800, in formation, was made with Bill in a Lockheed F-104 (826), Gordon Fullerton in a Northrop T-38, and Jim Smolka in a McDonnell Douglas F/A-18 (841) on March 23, 1990. The F-18 (841), standing on the NASA ramp is a backdrop for the photo of (Left to Right) James W. (Smoke) Smolka, C. Gordon Fullerton, Edward T. (Ed) Schneider, William H. (Bill) Dana, Stephen D. (Steve) Ishmael, Rogers E. Smith, and Thomas C. (Tom) McMurtry. Smolka joined NASA Ames-Dryden Flight Research Facility in September 1985. He has been the project pilot on the F-15 Advanced Control Technology for Integrated Vehicles (ACTIVE) research and F-15 Aeronautical Research Aircraft programs. He has also flown as a pilot on the NASA B-52 launch aircraft, as a co-project pilot on the F-16XL Supersonic Laminar Flow Control aircraft and the F-18 High Angle-of-Attack Research Vehicle (HARV) aircraft. Other aircraft he has flown in research programs are the F-16, F-111, F-104 and the T-38 as support. Fullerton, joined NASA's Ames-Dryden Flight Research Facility in November 1986. He was project pilot on the NASA/Convair 990 aircraft to test space shuttle landing gear components, project pilot on the F-18 Systems Research Aircraft, and project pilot on the B-52 launch aircraft, where he was involved in six air launches of the commercially developed Pegasus space launch vehicle. Other assignments include a variety of flight research and support activities in multi-engine and high performance aircraft such as, F-15, F-111, F-14, X-29, MD-11 and DC-8. Schneider arrived at the NASA Ames-Dryden Flight Research Facility on July 5, 1982, as a Navy Liaison Officer, becoming a NASA research

  13. MULTIPLICACIÓN Y TUBERIZACIÓN in vitro DE ÑAME (Dioscorea alata L. EN SISTEMA DE INMERSIÓN TEMPORAL MULTIPLICATION AND in vitro TUBERIZATION OF YAM (Dioscorea alata L. IN TEMPORARY IMMERSION SYSTEM

    Directory of Open Access Journals (Sweden)

    Robinson Salazar Díaz

    2007-12-01

    Full Text Available Se realizó la estandarización de la multiplicación y tuberización in vitro de ñame (Dioscorea alata L. utilizando el sistema de inmersión temporal conocido como RITA®. Se evaluó inicialmente el porcentaje de brotación de segmentos nodales en medio de cultivo semisólido utilizando dos tipos de citoquininas (BAP y Kinetina. Las plantas obtenidas fueron subcultivadas cada cuatro semanas y luego utilizadas para la obtención de meristemos y plántulas para llevar a cabo los diferentes experimentos en sistema de inmersión temporal. Se obtuvo un mayor porcentaje de explantes brotados al utilizar Kinetina. Con el sistema RITA® se evaluó el efecto de la densidad de explantes sobre la tasa de multiplicación y sobre la inducción, formación y desarrollo de microtubérculos, no encontrándose diferencias estadísticamente significativas entre las densidades evaluadas. De igual manera, se evaluó el efecto de diferentes frecuencias y tiempos de inmersión sobre la tasa de multiplicación, encontrándose que a una frecuencia de inmersión cada 12 horas y durante 10 minutos se obtenía la formación de mayor número de nudos y mayor tamaño de las plantas a las cuatro semanas de cultivo. Al utilizar el sistema de inmersión temporal se alcanzaron mayores tasas de multiplicación y tuberización in vitro comparadas con el sistema de cultivo convencional. Demostrándose así, el potencial de estos sistemas para implementar un programa de producción de semillas de ñame.Multiplication rate and in vitro tuberización of yam (Dioscorea alata L. was made using the temporary immersion system RITA®. Shoot percentage of nodal segments was initially evaluated in semisolid medium using two cytokinin types ((BAP and Kinetin. The obtained plants were subcultured every four weeks and then used to obtain meristems and plantlets to carry out different experiments in temporary immersion system. A higher sprouted explants percentage was obtained when using

  14. Evaluación en campo de plantas de ñame (Dioscorea alata L. obtenidas de los microtubérculos formados en Sistema de Inmersión Temporal

    Directory of Open Access Journals (Sweden)

    Manuel Cabrera Jova

    2010-06-01

    Full Text Available Los microtubérculos en algunas especies de plantas constituyen una importante alternativa como material vegetal de plantación. Se definió como objetivo de trabajo evaluar en campo la respuesta morfoagronómica de las plantas obtenidas de los microtubérculos de ñame formados en Sistema de Inmersión Temporal (SIT. Como variantes experimentales se plantaron tres categorías de microtubérculos, clasificados según su masa fresca (I. de 0,5 a 0,9 g; II. de 1,0 a 2,9 g; III. igual o mayor de 3,0 g, plantas in vitro previamente aclimatadas y corona de tubérculo. Se evaluó el efecto de la masa fresca de los microtubérculos sobre su brote, supervivencia y posterior desarrollo de las plantas derivadas de ellos en campo. Con los microtubérculos de ñame, con una masa fresca igual o superior a 3,0 g, se alcanzó el más alto porcentaje de brotación (91,30% y supervivencia de las plantas (96,50%, así como las mejores respuestas en los caracteres cuantitativos que se evaluaron en campo. Estos resultados confirmaron la importancia de la masa fresca de los microtubérculos para ser empleados como material vegetal de plantación directo en campo. Palabras clave: microtubérculos, plantas in vitro, campo. Abreviaturas: SIT sistema de Inmersión Temporal, gMF gramos de masa fresca Abstract: The microtuber in some plant species are an important alternative crop planting material. Objective was defined as field work to evaluate the response of plants obtained morphoagronomic of yam microtubers formed in Temporary Immersion System. Experimental variants were planted microtubers three categories classified by fresh mass (I. 0.5 to 0.9 g; II. from 1.0 to 2.9 g; III. equal to or greater than 3.0 g , plants previously acclimated in vitro and crown of the tuber. The effect of the fresh weight of microtubers on their sprouting, survival and further development of the plants derived from them in the field. Microtubers were achieved with the yam with a fresh

  15. Final report, Ames Mobile Laboratory Project: The development and operation of instrumentation in a mobile laboratory for in situ, real-time screening and characterization of soils using the laser ablation sampling technique

    International Nuclear Information System (INIS)

    The main focus of the Ames Laboratory's Technology Integration Program, TIP, from May 1991 through December 1994 was the development, fabrication, and demonstration of a mobile instrumentation laboratory incorporating rapid in situ sampling systems for safe, rapid, and cost effective soil screening/characterization. The Mobile Demonstration Laboratory for Environmental Screening Technologies, MDLEST, containing the analysis instrumentation, along with surface and subsurface sampling probe prototypes employing the laser ablation sampling technique were chosen to satisfy the particular surface and subsurface soil characterization needs of the various Department of Energy facilities for determining the extent of heavy metal and radionuclide contamination. The MDLEST, a 44 foot long 5th wheel trailer, is easily configured for the analysis instrumentation and sampling system required for the particular site work. This mobile laboratory contains all of the utilities needed to satisfy the operating requirements of the various instrumentation installed. These utilities include, an electric generator, a chilled water system, process gases, a heating/air conditioning system, and computer monitoring and automatic operating systems. Once the MDLEST arrives at the job site, the instrumentation is aligned and calibration is completed, sampling and analysis operations begin. The sample is acquired, analyzed and the results reported in as little as 10 minutes. The surface sampling probe is used in two modes to acquire samples for analysis. It is either set directly on the ground over the site to be sampled, in situ sampling, or in a special fixture used for calibrating the sampling analysis system with standard soil samples, having the samples brought to the MDLEST. The surface sampling probe was used to in situ sample a flat concrete surface (nondestructively) with the ablated sample being analyzed by the instrumentation in the MDLEST

  16. Diversidad genética intra e inter-específica de ñame (Dioscorea spp. de la región Caribe de Colombia mediante marcadores AFLP

    Directory of Open Access Journals (Sweden)

    Hernando Javier Rivera-Jiménez

    2011-12-01

    Full Text Available Conocer la variabilidad genética del ñame, Dioscorea spp., permite apoyar estrategias de mejoramiento y conservación de este recurso fitogenético. El objetivo de este estudio fue la caracterización molecular de 20 accesiones de Dioscorea spp. mediante la técnica molecular de AFLP para determinar cómo se distribuye la variabilidad genética de manera intra e inter-específica. Los datos fueron analizados mediante los métodos de agrupación de correspondencia múltiple y análisis de similaridad de Dice, estableciendo los niveles de confiabilidad de los grupos genéticos mediante remuestreos. En términos de diversidad interespecífica, los valores promedios de similitud variaron entre 41.81% entre D. alata L. y D. rotundata Poir., y 33.51% entre D. trifida L.f. y D. esculenta (Lour. Burkill, lo que sugiere alta diversidad genética entre las accesiones estudiadas, que formaron cuatro grupos genéticos: D. alata, D. rotundata, D. esculenta y D. trifida, confirmando correspondencia entre la caracterización morfológica, clasificación botánica y la caracterización molecular. En términos de diversidad intraespecífica para la especie D. alata, el análisis también reveló una composición heterogénea en la región Caribe colombiana. Estos estudios ayudarán a definir una estrategia adecuada para fines de conservación y apoyar los esfuerzos futuros en los programas de mejoramiento genético.

  17. Tests Related to Pregnancy

    Science.gov (United States)

    ... to learn. Search form Search Tests related to pregnancy You are here Home Testing & Services Testing for ... to Genetic Counseling . What Are Tests Related to Pregnancy? Pregnancy related testing is done before or during ...

  18. Anthrax - blood test

    Science.gov (United States)

    ... The best test for diagnosing anthrax is a culture of affected tissue or blood. Alternative Names Anthrax serology test; Antibody test for anthrax; Serologic test for B anthracis Images Blood test Bacillus anthracis References Hall GS, Woods GL. Medical bacteriology. ...

  19. Establishment of a Beta Test Center for the NPARC Code at Central State University

    Science.gov (United States)

    Okhio, Cyril B.

    1996-01-01

    Central State University has received a supplementary award to purchase computer workstations for the NPARC (National Propulsion Ames Research Center) computational fluid dynamics code BETA Test Center. The computational code has also been acquired for installation on the workstations. The acquisition of this code is an initial step for CSU in joining an alliance composed of NASA, AEDC, The Aerospace Industry, and academia. A post-Doctoral research Fellow from a neighboring university will assist the PI in preparing a template for Tutorial documents for the BETA test center. The major objective of the alliance is to establish a national applications-oriented CFD capability, centered on the NPARC code. By joining the alliance, the BETA test center at CSU will allow the PI, as well as undergraduate and post-graduate students to test the capability of the NPARC code in predicting the physics of aerodynamic/geometric configurations that are of interest to the alliance. Currently, CSU is developing a once a year, hands-on conference/workshop based upon the experience acquired from running other codes similar to the NPARC code in the first year of this grant.

  20. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions.

    Science.gov (United States)

    Hoorn, A J

    1989-04-01

    Dimethylglycine (DMG) and the chemically related amino acids glycine, sarcosine (monomethylglycine) and betaine (trimethylglycine) were tested in Salmonella typhimurium strain TA100 after treatment with sodium nitrite under acidic conditions using a modified Ames Salmonella/microsome assay as reported by Colman et al. (1980). The increase in the number of revertants observed both with and without metabolic activation was also induced in the control mixtures without adding the amines. From the subsequent testing of the individual components of the mixtures, we concluded that non-consumed nitrite was responsible for the mutagenic responses observed in the different reaction mixtures, and not the amines themselves. There were no consistent indications of mutagenic activity of the DMG test mixture as compared to the control mixture which exhibited both consistent mutagenic activity and a toxic effect which was not increased by the addition of DMG. In fact, DMG seemed to decrease the toxicity of the control reaction solution to the Salmonella which was clearly observed at the higher doses. DMG cannot be considered mutagenic under the test conditions employed. The same can be said of the other amino acids as well. PMID:2468082

  1. Evaluation of vinyl laurate in a battery of in vitro and in vivo tests for genotoxicity.

    Science.gov (United States)

    van Acker, Frédérique; Messinger, Horst; Bär, Albert

    2015-06-01

    Vinyl laurate is a potential residual monomer in chewing gum base formulated with polyvinyl acetate vinyl laurate copolymer (PVAcVL). The genotoxic potential of vinyl laurate was examined in a battery of in vitro and in vivo genotoxicity tests. Vinyl laurate was not mutagenic in Ames tests. In addition, it was not mutagenic in the HPRT mutation assay in L5178Y cells. An in vitro mammalian chromosome aberration assay performed in CHO cells was equivocal. Vinyl laurate and/or its metabolites were not clastogenic in the mouse bone marrow micronucleus test. Kinetic data indicate that VL is metabolised to acetaldehyde and lauric acid. Both metabolites are well known and have been studied previously. Model calculations show, that any exposure to acetaldehyde from the consumption of PVAcVL containing chewing gum will remain far below levels of acetaldehyde exposure from food in which acetaldehyde occurs naturally. Direct exposure to VL will primarily be at the site of entry. The lack of toxicity in a 90-day repeated dose toxicity test, performed with VL doses up to approximately 3000 times higher than the maximal VL intake from the consumption of a typical piece of chewing gum, demonstrates a high safety margin. PMID:25445001

  2. Tests in contingency tables as regression tests

    OpenAIRE

    Stanislav Anatolyev; Grigory Kosenok

    2006-01-01

    Applied researchers often use tests based on contingency tables in preliminary data analysis and diagnostic testing. We show that many of such tests may be alternatively implemented by testing for coecient restrictions in linear regression systems (as a rule, employing the Wald test). This uni es the theories of regression analysis and contingency tables, sheds more light on intuitive contents of contingency table tests, and provides a more convenient and familiar tool for practitioners.

  3. TEST SUITE GENERATION PROCESS FOR AGENT TESTING

    Directory of Open Access Journals (Sweden)

    HOUHAMDI ZINA

    2011-04-01

    Full Text Available Software agents are a promising technology for today's complex, distributed systems. Methodologies and techniques that address testing and reliability of multi agent systems are increasingly demanded, in particular to support automated test case generation and execution. In this paper, we introduce a novel approach for goal-oriented software agent testing. It specifies a testing process that complements the goal oriented methodology Tropos and reinforces the mutual relationship between goal analysis and testing. Furthermore, it defines a structured and comprehensive agent test suite generation process by providing a systematic way of deriving test cases from goal analysis.

  4. Design Driven Testing Test Smarter, Not Harder

    CERN Document Server

    Stephens, M

    2010-01-01

    The groundbreaking book Design Driven Testing brings sanity back to the software development process by flipping around the concept of Test Driven Development (TDD) - restoring the concept of using testing to verify a design instead of pretending that unit tests are a replacement for design. Anyone who feels that TDD is "Too Damn Difficult" will appreciate this book. Design Driven Testing shows that, by combining a forward-thinking development process with cutting-edge automation, testing can be a finely targeted, business-driven, rewarding effort. In other words, you'll learn how to test

  5. Learning software testing with Test Studio

    CERN Document Server

    Madi, Rawane

    2013-01-01

    Learning Software Testing with Test Studio is a practical, hands-on guide that will help you get started with Test Studio to design your automated solution and tests. All through the book, there are best practices and tips and tricks inside Test Studio which can be employed to improve your solution just like an experienced QA.If you are a beginner or a professional QA who is seeking a fast, clear, and direct to the point start in automated software testing inside Test Studio, this book is for you. You should be familiar with the .NET framework, mainly Visual Studio, C#, and SQL, as the book's

  6. Study of the heavy ions (Au+Au at 150 AMeV) collisions with the FOPI detector. Comparison with the Landau-Vlasov model; Etude des collisions d`ions lourds AU+AU a 150 A.MeV avec le detecteur FOPI. Comparaison avec le modele de Landau-Vlasov

    Energy Technology Data Exchange (ETDEWEB)

    Boussange, S.

    1995-09-15

    In this thesis, heavy ions (Au+Au) collisions experiments are made at 150 AMeV.In the first part, a general study of the nuclear matter equation is presented. Then the used Landau-Vlasov theoretical model is describe. The third part presents the FOPI experience and the details of how to obtain this theoretical predictions (filter, cuts, corrections, possible centrality selections).At the end, experimental results and comparisons with the Landau-Vlasov model are presented. (TEC). 105 refs., 96 figs., 14 tabs.

  7. Obtención de ácido láctico por fermentación de almidón de ñame espino mediante el Lactobacillus delbrueckii ssp. bulgaricus y el Streptococcus thermophilus para su uso en la producción de ácido poliláctico

    OpenAIRE

    Tejada Tovar, Ronald Eduardo

    2015-01-01

    Resumen: El propósito del presente trabajo fue evaluar la producción de ácido láctico obtenido por la fermentación del almidón de ñame espino Discorea rotundata mediante la acción de la mezcla de Lactobacillus delbrueckii ssp. bulgaricus y el Streptococcus thermophilus, para su posible uso en la obtención de APL; estableciendo el proceso de obtención y caracterizando el producto obtenido mediante análisis de sus propiedades fisicoquímicas y funcionales; a este se le realizó un seguimiento med...

  8. Lactose tolerance tests

    Science.gov (United States)

    Hydrogen breath test for lactose tolerance ... Two common methods include: Lactose tolerance blood test Hydrogen breath test The hydrogen breath test is the preferred method. It measures the amount of hydrogen ...

  9. Direct Antiglobulin Test

    Science.gov (United States)

    ... this page helpful? Also known as: DAT; Direct Coombs Test; Direct Anti-human Globulin Test Formal name: ... antiglobulin test (DAT), also known as the direct Coombs test, is used primarily to help determine whether ...

  10. Ketones urine test

    Science.gov (United States)

    Ketone bodies - urine; Urine ketones; Ketoacidosis - urine ketones test; Diabetic ketoacidosis - urine ketones test ... Urine ketones are usually measured as a "spot test." This is available in a test kit that ...

  11. Sweat electrolytes test

    Science.gov (United States)

    Sweat test; Sweat chloride; Iontophoretic sweat test ... No special steps are needed before this test. ... The test is not painful. Some people have a tingling feeling at the site of the electrode. This feeling ...

  12. Lab and Imaging Tests

    Science.gov (United States)

    ... Information Treatment Lab and Imaging Tests Lab and Imaging Tests Lab and Imaging Tests SHARE: Print Glossary Doctors use several different lab and imaging tests to help detect (diagnose) a blood cancer ( ...

  13. Coccidioides precipitin test

    Science.gov (United States)

    Coccidioidomycosis antibody test ... There is no special preparation for the test. ... The precipitin test is one of several tests that can be done to determine if you are infected with the fungus ...

  14. Genetic Testing (For Parents)

    Science.gov (United States)

    ... Story" 5 Things to Know About Zika & Pregnancy Genetic Testing KidsHealth > For Parents > Genetic Testing Print A A ... blood, skin, bone, or other tissue is needed. Genetic Testing During Pregnancy For genetic testing before birth, pregnant ...

  15. Genetic Testing for ALS

    Science.gov (United States)

    ... your area, please visit www.nsgc.org . Genetic Testing Genetic testing can help determine the cause of FALS ... couples planning on having children to pursue prenatal testing. Genetic testing does not: Currently change medical treatment. Diagnose ...

  16. Intelligent test integration system

    Science.gov (United States)

    Sztipanovits, J.; Padalkar, S.; Rodriguez-Moscoso, J.; Kawamura, K.; Purves, B.; Williams, R.; Biglari, H.

    1988-01-01

    A new test technology is described which was developed for space system integration. The ultimate purpose of the system is to support the automatic generation of test systems in real time, distributed computing environments. The Intelligent Test Integration System (ITIS) is a knowledge based layer above the traditional test system components which can generate complex test configurations from the specification of test scenarios.

  17. Diversidad genética intra e inter-específica de ñame (Dioscorea spp. de la región Caribe de Colombia mediante marcadores AFLP

    Directory of Open Access Journals (Sweden)

    Alvarez Soto Andres

    2011-12-01

    Full Text Available Conocer la variabilidad genética del ñameDioscorea spp., permite apoyar estrategias de mejoramiento y conservación de este recurso fitogenético. El objetivo de este estudio fue la caracterización molecular de 20 accesiones de Dioscorea spp. mediante la técnica molecular de AFLP para determinar cómo se distribuye la variabilidad genética de manera intra e inter-específica. Los datos fueron analizados mediante los métodos de agrupación de correspondencia múltiple y análisis de similaridad de Dice, estableciendo los niveles de confiabilidad de los grupos genéticos mediante remuestreos. En términos de diversidad interespecífica, los valores promedios de similitud variaron entre 41.81% entre D. alata L. y D. rotundata Poir., y 33.51% entre D. trifida L.f. y D. esculenta (Lour. Burkill, lo que sugiere alta diversidad genética entre las accesiones estudiadas, que formaron cuatro grupos genéticos: D. alataD. rotundataD. esculenta y D. trifida, confirmando correspondencia entre la caracterización morfológica, clasificación botánica y la caracterización molecular. En términos de diversidad intraespecífica para la especie D. alata, el análisis también reveló una composición heterogénea en la región Caribe colombiana. Estos estudios ayudarán a definir una estrategia adecuada para fines de conservación y apoyar los esfuerzos futuros en los programas de mejoramiento genético.

  18. Comparison of the NASA Common Research Model European Transonic Wind Tunnel Test Data to NASA Test Data (Invited)

    OpenAIRE

    Rivers, Melissa; QUEST, Juergen; Rudnik, Ralf

    2015-01-01

    Experimental aerodynamic investigations of the NASA Common Research Model have been conducted in the NASA Langley National Transonic Facility, the NASA Ames 11-ft wind tunnel, and the European Transonic Wind Tunnel. In the NASA Ames 11-ft wind tunnel, data have been obtained at only a chord Reynolds number of 5 million for a wing/body/tail = 0 degree incidence configuration. Data have been obtained at chord Reynolds numbers of 5, 19.8 and 30 million for the same configuration in the Nation...

  19. To test or not to test

    DEFF Research Database (Denmark)

    Rochon, Justine; Gondan, Matthias; Kieser, Meinhard

    2012-01-01

    Background: Student's two-sample t test is generally used for comparing the means of two independent samples, for example, two treatment arms. Under the null hypothesis, the t test assumes that the two samples arise from the same normally distributed population with unknown variance. Adequate...... control of the Type I error requires that the normality assumption holds, which is often examined by means of a preliminary Shapiro-Wilk test. The following two-stage procedure is widely accepted: If the preliminary test for normality is not significant, the t test is used; if the preliminary test rejects...... the null hypothesis of normality, a nonparametric test is applied in the main analysis. Methods: Equally sized samples were drawn from exponential, uniform, and normal distributions. The two-sample t test was conducted if either both samples (Strategy I) or the collapsed set of residuals from both samples...

  20. CANFLEX fuel bundle strength tests (test report)

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Seok Kyu; Chung, C. H.; Kim, B. D.

    1997-08-01

    This document outlines the test results for the strength tests of the CANFLEX fuel bundle. Strength tests are performed to determine and verify the amount of the bundle shape distortion which is against the side-stops when the bundles are refuelling. There are two cases of strength test; one is the double side-stop test which simulates the normal bundle refuelling and the other is the single side-stop test which simulates the abnormal refuelling. the strength test specification requires that the fuel bundle against the side-stop(s) simulators for this test were fabricated and the flow rates were controlled to provide the required conservative hydraulic forces. The test rig conditions of 120 deg C, 11.2 MPa were retained for 15 minutes after the flow rate was controlled during the test in two cases, respectively. The bundle loading angles of number 13- number 15 among the 15 bundles were 67.5 deg CCW and others were loaded randomly. After the tests, the bundle shapes against the side-stops were measured and inspected carefully. The important test procedures and measurements were discussed as follows. (author). 5 refs., 22 tabs., 5 figs.

  1. CANFLEX fuel bundle strength tests (test report)

    International Nuclear Information System (INIS)

    This document outlines the test results for the strength tests of the CANFLEX fuel bundle. Strength tests are performed to determine and verify the amount of the bundle shape distortion which is against the side-stops when the bundles are refuelling. There are two cases of strength test; one is the double side-stop test which simulates the normal bundle refuelling and the other is the single side-stop test which simulates the abnormal refuelling. the strength test specification requires that the fuel bundle against the side-stop(s) simulators for this test were fabricated and the flow rates were controlled to provide the required conservative hydraulic forces. The test rig conditions of 120 deg C, 11.2 MPa were retained for 15 minutes after the flow rate was controlled during the test in two cases, respectively. The bundle loading angles of number 13- number 15 among the 15 bundles were 67.5 deg CCW and others were loaded randomly. After the tests, the bundle shapes against the side-stops were measured and inspected carefully. The important test procedures and measurements were discussed as follows. (author). 5 refs., 22 tabs., 5 figs

  2. Hot-Fire Testing of 100 LB(sub F) LOX/LCH4 Reaction Control Engine at Altitude Conditions

    Science.gov (United States)

    Marshall, William M.; Kleinhenz, Julie E.

    2010-01-01

    Liquid oxygen/liquid methane (LO2/LCH4 ) has recently been viewed as a potential green propulsion system for both the Altair ascent main engine (AME) and reaction control system (RCS). The Propulsion and Cryogenic Advanced Development Project (PCAD) has been tasked by NASA to develop these green propellant systems to enable safe and cost effective exploration missions. However, experience with LO2/LCH4 as a propellant combination is limited, so testing of these systems is critical to demonstrating reliable ignition and performance. A test program of a 100 lb f reaction control engine (RCE) is underway at the Altitude Combustion Stand (ACS) of the NASA Glenn Research Center, with a focus on conducting tests at altitude conditions. These tests include a unique propellant conditioning feed system (PCFS) which allows for the inlet conditions of the propellant to be varied to test warm to subcooled liquid propellant temperatures. Engine performance, including thrust, c* and vacuum specific impulse (I(sub sp,vac)) will be presented as a function of propellant temperature conditions. In general, the engine performed as expected, with higher performance at warmer propellant temperatures but better efficiency at lower propellant temperatures. Mixture ratio effects were inconclusive within the uncertainty bands of data, but qualitatively showed higher performance at lower ratios.

  3. Flight test evaluation of the Stanford University/United Airlines differential GPS Category 3 automatic landing system

    Science.gov (United States)

    Kaufmann, David N.; Ncnally, B. David

    1995-01-01

    Test flights were conducted to evaluate the capability of Differential Global Positioning System (DGPS) to provide the accuracy and integrity required for International Civil Aviation Organization (ICAO) Category (CAT) 3 precision approach and landings. These test flights were part of a Federal Aviation Administration (FAA) program to evaluate the technical feasibility of using DGPS based technology for CAT 3 precision approach and landing applications. A United Airlines Boeing 737-300 (N304UA) was equipped with DGPS receiving equipment and additional computing capability provided by Stanford University. The test flights were conducted at NASA Ames Research Center's Crows Landing Flight Facility, Crows Landing, California. The flight test evaluation was based on completing 100 approaches and autolandings; 90 touch and go, and 10 terminating with a full stop. Two types of accuracy requirements were evaluated: 1) Total system error, based on the Required Navigation Performance (RNP), and 2) Navigation sensor error, based on ICAO requirements for the Microwave Landing System (MLS). All of the approaches and autolandings were evaluated against ground truth reference data provided by a laser tracker. Analysis of these approaches and autolandings shows that the Stanford University/United Airlines system met the requirements for a successful approach and autolanding 98 out of 100 approaches and autolandings, based on the total system error requirements as specified in the FAA CAT 3 Level 2 Flight Test Plan.

  4. Web Security Testing Cookbook

    CERN Document Server

    Hope, Paco

    2008-01-01

    Among the tests you perform on web applications, security testing is perhaps the most important, yet it's often the most neglected. The recipes in the Web Security Testing Cookbook demonstrate how developers and testers can check for the most common web security issues, while conducting unit tests, regression tests, or exploratory tests. Unlike ad hoc security assessments, these recipes are repeatable, concise, and systematic-perfect for integrating into your regular test suite.

  5. Automated functional software testing

    OpenAIRE

    Jelnikar, Kristina

    2009-01-01

    The following work describes an approach to software test automation of functional testing. In the introductory part we are introducing what testing problems development companies are facing. The second chapter describes some testing methods, what role does testing have in software development, some approaches to software development and the meaning of testing environment. Chapter 3 is all about test automation. After a brief historical presentation, we are demonstrating through s...

  6. Identificación, establecimiento in vitro y análisis fitoquímico preliminar de especies silvestres de ñame (Dioscorea spp. empleadas con fines medicinales

    Directory of Open Access Journals (Sweden)

    Víctor Andrés Ramos Duarte

    2015-05-01

    Full Text Available Título en ingles: Identification, in vitro establishment and preliminary phytochemical analysis of wild yam (Dioscorea spp. used for medicinal purposesTítulo corto: Identificación, establecimiento in vitro y análisis fitoquímico preliminar de especies silvestres de ñameResumen:  Tubérculos del género Dioscorea comercializados con fines medicinales, fueron recolectados con el propósito de lograr su establecimiento a condiciones in vitro. Previamente se lograron identificar taxonómicamente las especies y por medio de análisis fitoquímicos demostrar su potencial farmacéutico. El material recolectado fue identificado como Dioscorea coriacea, D. lehmannii, D. meridensis, D. polygonoides y una especie comestible D. trifida. Tubérculos recolectados de centros de acopio y traídos de campo fueron lavados, desinfectados, asperjados con Ácido Giberélico (AG3 y sembrados en sustrato BM-2®, en invernadero a 18°C día y 10°C noche. Los tubérculos completos o por secciones fueron almacenados en bolsas herméticas a temperatura ambiente. Posteriormente se desinfectó material vegetal de las especies D. coriacea, D. lehmannii, D. meridensis y D polygonoides, seleccionando explantes de brotes sanos (D. coriacea / laboratorio para su establecimiento. Se evaluaron tres medios de cultivo para establecimiento, el que presentó los mejores resultados fue Medio Murashige & Skoog (1962 suplementado con BAP 1 mL/L, AG3 1 mL/L y Putrescina 2 mL/L. Para la extracción y análisis de metabolitos secundarios se utilizaron tubérculos de D. coriacea, D. lehmannii y D. polygonoides, empleando como solvente de extracción metanol. Se  encontró mayor concentración de extracto vegetal en D. coriacea (54%, y mediante cromatografía en capa delgada (CCD, se confirmó la presencia de saponinas, que resultó mayor en comparación con D. polygonoides especie reconocida por su alto contenido de saponinas. Estos resultados permitirán realizar análisis m

  7. Get Tested for HIV

    Science.gov (United States)

    ... Submit Home > HIV/AIDS > Get tested for HIV HIV/AIDS This information in Spanish ( en español ) Get tested for HIV When should I get tested for HIV? Types ... to top More information on Get tested for HIV Explore other publications and websites HIV Anonymous Testing, ...

  8. CO2 blood test

    Science.gov (United States)

    Bicarbonate test; HCO3-; Carbon dioxide test; TCO2; Total CO2; CO2 test - serum ... Many medicines can interfere with blood test results. Your health care provider will tell you if you need to stop taking any medicines before you have this test. DO ...

  9. Growth hormone stimulation test

    Science.gov (United States)

    Arginine test; Arginine-GHRH test ... of re-inserting the needle each time. The test takes between 2 to 5 hours. The procedure ... eat for 10 to 12 hours before the test. Eating food can change the test results. Some ...

  10. Boeing Smart Rotor Full-scale Wind Tunnel Test Data Report

    Science.gov (United States)

    Kottapalli, Sesi; Hagerty, Brandon; Salazar, Denise

    2016-01-01

    A full-scale helicopter smart material actuated rotor technology (SMART) rotor test was conducted in the USAF National Full-Scale Aerodynamics Complex 40- by 80-Foot Wind Tunnel at NASA Ames. The SMART rotor system is a five-bladed MD 902 bearingless rotor with active trailing-edge flaps. The flaps are actuated using piezoelectric actuators. Rotor performance, structural loads, and acoustic data were obtained over a wide range of rotor shaft angles of attack, thrust, and airspeeds. The primary test objective was to acquire unique validation data for the high-performance computing analyses developed under the Defense Advanced Research Project Agency (DARPA) Helicopter Quieting Program (HQP). Other research objectives included quantifying the ability of the on-blade flaps to achieve vibration reduction, rotor smoothing, and performance improvements. This data set of rotor performance and structural loads can be used for analytical and experimental comparison studies with other full-scale rotor systems and for analytical validation of computer simulation models. The purpose of this final data report is to document a comprehensive, highquality data set that includes only data points where the flap was actively controlled and each of the five flaps behaved in a similar manner.

  11. Modulation of Mutagenicity of Various Mutagens by Shrimp Flesh and Skin Extracts in Salmonella Test

    Directory of Open Access Journals (Sweden)

    S. Mehrabian

    2006-01-01

    Full Text Available Many mutagens and carcinogens may act through the generation of Reactive Oxygen Species (ROS in cells that maybe related to cancer. The carotenoid astaxanthin-the red pigment for the attractive coloration in the skin and flesh of shrimp-has attracted considerable interest in recent years because of its superior antioxidative activity to most of the hydrophobic antioxidants. According to the important role of carotenoids in human health, the main carotenoid pigment in flesh and by-products of the different shrimp species from penaeidae family-Astaxanthin-was extracted and separated by thin layer chromatography using silica gel, subsequently. The identifications were confirmed by fourier transform infrared (ET-IR spectroscopy. The effect of these extracts on mutagenicity and carcinogenicity induced by Sodium Azide and potassium permanganate was investigated in bacterial assay system, i.e., the Ames test with salmonella typhimurium TA100, TA104. These strains have a certain mutation in their histidin operon, which are related to the external histidin source. Such a mutation can be reversed through contact with a diagnostic mutagen, but in shrimp extracts prevented from effect of this mutagen in which, after repeated test series under standardized condition, the anticarcinogenic effect of flesh and skin of shrimp was proven and the shrimp skin showed stronger anticarcinogenic effect in comparison with shrimp flesh. Different shrimp species from penaeidae family indicated similar antricariongenic effects.

  12. Characterization of biological activity of cigarette smoke using in vitro tests

    International Nuclear Information System (INIS)

    Studies were conducted to characterize the influence of exposure mode (whole-body continuous, nose only intermittent, nose-only continuous) on biological activity of cigarette smoke condensates. The mutagenic potency of the extracts was determined using Salmonella typhimurium tester strain TA-98 with and without the addition of S-9. The cytotoxicity of the cigarette smoke with and without the addition of S-9 was also determined using Chinese hamster ovary cells (CHO). Mutagenic activity was observed in the Ames test only after the addition of S-9. The optimum mutagenic activity was observed following addition of between 3 and 6% S-9. The average mutagenic potency, when cells were tested at the optimum level of S-9, was 1.5 revertants/mg extract. Cell killing by cigarette smoke extracts was the same for extracts derived from all three exposure modes. There was about 20% cell killing at concentrations of 300 mg extract/mL culture media. No differences were observed in either mutagenic or cytotoxic potency among the smoke extracts produced under different exposure conditions. (author)

  13. Vendor System Vulnerability Testing Test Plan

    Energy Technology Data Exchange (ETDEWEB)

    James R. Davidson

    2005-01-01

    The Idaho National Laboratory (INL) prepared this generic test plan to provide clients (vendors, end users, program sponsors, etc.) with a sense of the scope and depth of vulnerability testing performed at the INL’s Supervisory Control and Data Acquisition (SCADA) Test Bed and to serve as an example of such a plan. Although this test plan specifically addresses vulnerability testing of systems applied to the energy sector (electric/power transmission and distribution and oil and gas systems), it is generic enough to be applied to control systems used in other critical infrastructures such as the transportation sector, water/waste water sector, or hazardous chemical production facilities. The SCADA Test Bed is established at the INL as a testing environment to evaluate the security vulnerabilities of SCADA systems, energy management systems (EMS), and distributed control systems. It now supports multiple programs sponsored by the U.S. Department of Energy, the U.S. Department of Homeland Security, other government agencies, and private sector clients. This particular test plan applies to testing conducted on a SCADA/EMS provided by a vendor. Before performing detailed vulnerability testing of a SCADA/EMS, an as delivered baseline examination of the system is conducted, to establish a starting point for all-subsequent testing. The series of baseline tests document factory delivered defaults, system configuration, and potential configuration changes to aid in the development of a security plan for in depth vulnerability testing. The baseline test document is provided to the System Provider,a who evaluates the baseline report and provides recommendations to the system configuration to enhance the security profile of the baseline system. Vulnerability testing is then conducted at the SCADA Test Bed, which provides an in-depth security analysis of the Vendor’s system.b a. The term System Provider replaces the name of the company/organization providing the system

  14. Results and Interpretation of the WFRD ELS Distillation Down-Select Test Data

    Science.gov (United States)

    Delzeit, Lance Dean; Flynn, Michael; Carter, Layne; Long, David A.

    2010-01-01

    Testing of the Wiped-film Rotating-disk (WFRD) evaporator was conducted in support of the Exploration Life Support Distillation Down-Select Test. The WFRD was constructed at NASA Ames Research Center (ARC) and tested at NASA Marshall Space Flight Center (MSFC). The WFRD was delivered to MSFC in September 2009, and testing of solution #1 and solution #2 immediately following. Solution #1 was composed of humidity condensate and urine, including flush water and pretreatment chemicals. Solution #2 was composed of hygiene water, humidity condensate, and urine, including flush water and pretreatment chemicals. During the testing, the operational parameters of the WFRD were recorded and samples of the feed, brine, and product were collected and analyzed. The steady-state results of processing 414L of feed solution #1 and 1283L of feed solution #2 demonstrated that running the WFRD at a brine temperature of 50 C gave an average production rate of 16.7 L/hr. The specific energy consumption was 80.5W-hr/L. Data Analysis shows that the water recovery rates were 94% and 91%, respectively. The total mass of the WFRD as delivered to MSFC was 300 Kg. The volume of the tests stand rack was 1m width x 0.7m depth x 1.9m height or 1.5 cu m of which about half of the total volume is occupied by equipment. Chemical analysis of the distillate showed an average TOC of 20ppm, a pH of 3.5, and a conductivity of 98 mho/cm. The conductivity of the distillate, compared to the feed, decreased by 98.9%., the total ion concentration decreased by 99.6%, the total organics decreased 98.6%, and the metals were at or below detection limits

  15. Campylobacter serology test

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003530.htm Campylobacter serology test To use the sharing features on this page, please enable JavaScript. Campylobacter serology test is a blood test to look ...

  16. Mark 1 Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Mark I Test Facility is a state-of-the-art space environment simulation test chamber for full-scale space systems testing. A $1.5M dollar upgrade in fiscal year...

  17. Structural Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Provides a wide variety of testing equipment, fixtures and facilities to perform both unique aviation component testing as well as common types of materials testing...

  18. Hepatitis A Test

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Hepatitis A Testing Share this page: Was this page ... HAV-Ab total; Anti-HAV Formal name: Viral Hepatitis A Antibody Related tests: Hepatitis B Testing ; Hepatitis ...

  19. CSF-VDRL test

    Science.gov (United States)

    Venereal disease research laboratory slide test - CSF ... provider's instructions on how to prepare for this test. ... The CSF-VDRL test is done to diagnose syphilis in the brain or spinal cord. Brain and spinal cord involvement is often a ...

  20. Stomach acid test

    Science.gov (United States)

    Gastric acid secretion test ... The test is done after you have not eaten for a while so fluid is all that remains in ... injected into your body. This is done to test the ability of the cells in the stomach ...

  1. ALP isoenzyme test

    Science.gov (United States)

    Alkaline phosphatase isoenzyme test ... anything for 10 to 12 hours before the test, unless your health care provider tells you to do so. Many medicines can interfere with blood test results. Your health care provider will tell you ...

  2. PBG urine test

    Science.gov (United States)

    Porphobilinogen test ... temporarily stop taking medicines that may affect the test results. Be sure to tell your provider about ... This test involves only normal urination, and there is no discomfort.

  3. Sickle cell test

    Science.gov (United States)

    Sickledex; Hgb S test ... This test is done to tell if a person has abnormal hemoglobin that causes sickle cell disease and sickle ... and no symptoms, or only mild ones. This test does not tell the difference between these two ...

  4. Breath alcohol test

    Science.gov (United States)

    Alcohol test - breath ... There are various brands of breath alcohol tests. Each one uses a different method to test the level of alcohol in the breath. The machine may be electronic or manual. One ...

  5. Vitamin A Test

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Vitamin A Share this page: Was this page helpful? ... Related tests: Complete Blood Count , Comprehensive Metabolic Panel , Vitamin B12 and Folate , Vitamin D Tests , Iron Tests , ...

  6. Creatine phosphokinase test

    Science.gov (United States)

    CPK test ... vein. The procedure is called a venipuncture . This test may be repeated over 2 or 3 days ... helps determine which tissue has been damaged. This test may be used to: Diagnose heart attack Evaluate ...

  7. Bone mineral density test

    Science.gov (United States)

    BMD test; Bone density test; Bone densitometry; DEXA scan; DXA; Dual-energy x-ray absorptiometry; p-DEXA; Osteoporosis-BMD ... need to undress. This scan is the best test to predict your risk of fractures. Peripheral DEXA ( ...

  8. Dexamethasone suppression test

    Science.gov (United States)

    DST; ACTH suppression test; Cortisol suppression test ... During this test, you will receive dexamethasone. This is a strong man-made (synthetic) glucocorticoid medication. Afterward, your blood is drawn ...

  9. Tests for Colorectal Cancer

    Science.gov (United States)

    ... symptoms Next Topic Colorectal cancer stages Tests for colorectal cancer Colorectal cancer is often found after symptoms appear, ... of the cancer . Imaging tests to look for colorectal cancer Imaging tests use sound waves, x-rays, magnetic ...

  10. Estradiol blood test

    Science.gov (United States)

    E2 test ... temporarily stop taking certain medicines that may affect test results. Be sure to tell your provider about ... helps prevent sperm from dying too early. This test may be ordered to check: How well your ...

  11. Service functional test automation

    OpenAIRE

    Hillah, Lom Messan; Maesano, Ariele-Paolo; Rosa, Fabio; Maesano, Libero; Lettere, Marco; Fontanelli, Riccardo

    2015-01-01

    This paper presents the automation of the functional test of services (black-box testing) and services architectures (grey-box testing) that has been developed by the MIDAS project and is accessible on the MIDAS SaaS. In particular, the paper illustrates the solutions of tough functional test automation problems such as: (i) the configuration of the automated test execution system against large and complex services architectures, (ii) the constraint-based test input generation, (iii) the spec...

  12. Small test SDHW systems

    DEFF Research Database (Denmark)

    Vejen, Niels Kristian

    1999-01-01

    Three small test SDHW systems was tested in a laboratory test facility.The three SDHW systems where all based on the low flow principe and a mantle tank but the design of the systems where different.......Three small test SDHW systems was tested in a laboratory test facility.The three SDHW systems where all based on the low flow principe and a mantle tank but the design of the systems where different....

  13. An Evaluation of MAPIA in Michigan as an Ante-Mortem Supplemental Test for Use in Suspect Tuberculosis Cattle

    Directory of Open Access Journals (Sweden)

    Scott D. Fitzgerald

    2012-01-01

    Full Text Available The objective of this study was to make use of bovine tuberculosis suspect cattle from the state of Michigan to validate a multiantigen print immunoassay for use on sera to serve as an improved supplementary ante-mortem test to increase specificity of current tuberculosis testing methods. Over a 27-month period, 234 sera were collected and tested by MAPIA method, which was evaluated using four different interpretation criteria. These results were subsequently compared to final mycobacterial culture and PCR results obtained by the National Veterinary Services Laboratories, Ames, IA, which served as the true indicator of the cattle’s tuberculosis infection status. This study indicates that an interpretation criterion which includes 3 or more positive reactions to the 11 different mycobacteria antigens utilized provided both an acceptable sensitivity (69.39% and a high specificity (90.27%. This MAPIA technique shows potential for eventual application as a supplementary ante-mortem tuberculosis serologic test following one of the various current or soon-to-be-approved whole herd screening assays as part of a tuberculosis eradication program.

  14. AUTOMATED API TESTING APPROACH

    Directory of Open Access Journals (Sweden)

    SUNIL L. BANGARE

    2012-02-01

    Full Text Available Software testing is an investigation conducted to provide stakeholders with information about the quality of the product or service under test. With the help of software testing we can verify or validate the software product. Normally testing will be done after development of software but we can perform the software testing at the time of development process also. This paper will give you a brief introduction about Automated API Testing Tool. This tool of testing will reduce lots of headache after the whole development of software. It saves time as well as money. Such type of testing is helpful in the Industries & Colleges also.

  15. Textiles Performance Testing Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — The Textiles Performance Testing Facilities has the capabilities to perform all physical wet and dry performance testing, and visual and instrumental color analysis...

  16. Electromagnetic Interface Testing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Electromagnetic Interface Testing facilitysupports such testing asEmissions, Field Strength, Mode Stirring, EMP Pulser, 4 Probe Monitoring/Leveling System, and...

  17. Mobile Test Capabilities

    Data.gov (United States)

    Federal Laboratory Consortium — The Electrical Power Mobile Test capabilities are utilized to conduct electrical power quality testing on aircraft and helicopters. This capability allows that the...

  18. GPS Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Global Positioning System (GPS) Test Facility Instrumentation Suite (GPSIS) provides great flexibility in testing receivers by providing operational control of...

  19. Test Control Center (TCC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Test Control Center (TCC) provides a consolidated facility for planning, coordinating, controlling, monitoring, and analyzing distributed test events. ,The TCC...

  20. FOOD SAFETY TESTING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory develops screening assays, tests and modifies biosensor equipment, and optimizes food safety testing protocols for the military and civilian sector...

  1. Test-methods on the test-bench: a comparison of complete exhaust and exhaust particle extracts for genotoxicity/mutagenicity assessment.

    Science.gov (United States)

    Steiner, Sandro; Heeb, Norbert V; Czerwinski, Jan; Comte, Pierre; Mayer, Andreas; Petri-Fink, Alke; Rothen-Rutishauser, Barbara

    2014-05-01

    With the growing number of new exhaust after-treatment systems, fuels and fuel additives for internal combustion engines, efficient and reliable methods for detecting exhaust genotoxicity and mutagenicity are needed to avoid the widespread application of technologies with undesirable effects toward public health. In a commonly used approach, organic extracts of particulates rather than complete exhaust is used for genotoxicity/mutagenicity assessment, which may reduce the reliability of the results. In the present study, we assessed the mutagenicity and the genotoxicity of complete diesel exhaust compared to an organic exhaust particle extract from the same diesel exhaust in a bacterial and a eukaryotic system, that is, a complex human lung cell model. Both, complete exhaust and organic extract were found to act mutagenic/genotoxic, but the amplitudes of the effects differed considerably. Furthermore, our data indicate that the nature of the mutagenicity may not be identical for complete exhaust and particle extracts. Because in addition, differences between the responses of the different biological systems were found, we suggest that a comprehensive assessment of exhaust toxicity is preferably performed with complete exhaust and with biological systems representative for the organisms and organs of interest (i.e., human lungs) and not only with the Ames test. PMID:24697289

  2. Localizing Test Power Consumption for Scan Testing

    Institute of Scientific and Technical Information of China (English)

    XIANG Dong; LI Kai-wei

    2005-01-01

    A two stage scan architecture is proposed to do low powerand low test application cost scan testing. The first stage includes multiple scan chains, where each scan chain is driven by a primary input. Each scan flip-flop in the multiple scan chains drives a group of scan flip-flops. The scan flip-flop in the multiple scan chain and the scan flipflop driven by it are assigned the same values for all test vectors. Scan flip-flops in the multiple scan chains and those in the second stage use separate clock signals, but the design for testability technqiue needs only one clock. The proposed scan architecture localizes test power consumption to the multiple scan chains during test application. Test signals assigned to scan flip-flops in the multiple scan chains are applied to the scan flip-flops in the second stage after the test vector has been applied to the multiple scan chains. This technique can make test power consumption very small.

  3. Digface characterization test plan (remote testing)

    Energy Technology Data Exchange (ETDEWEB)

    Croft, K.; Hyde, R.; Allen, S.

    1993-08-01

    The objective of the Digface Characterization (DFC) Remote Testing project is to remotely deploy a sensor head (Mini-Lab) across a digface to determine if it can characterize the contents below the surface. The purpose of this project is to provide a robotics technology that allows removal of workers from hazards, increases speed of operations, and reduces life cycle costs compared to alternate methods and technologies. The Buried Waste Integrated Demonstration (BWID) is funding the demonstration, testing, and evaluation of DFC. This document describes the test plan for the DFC remote deployment demonstration for the BWID. The purposes of the test plan are to establish test parameters so that the demonstration results are deemed useful and usable and perform the demonstration in a safe manner and within all regulatory requirements.

  4. Test report for core drilling ignitability testing

    International Nuclear Information System (INIS)

    Testing was carried out with the cooperation of Westinghouse Hanford Company and the United States Bureau of Mines at the Pittsburgh Research Center in Pennsylvania under the Memorandum of Agreement 14- 09-0050-3666. Several core drilling equipment items, specifically those which can come in contact with flammable gasses while drilling into some waste tanks, were tested under conditions similar to actual field sampling conditions. Rotary drilling against steel and rock as well as drop testing of several different pieces of equipment in a flammable gas environment were the specific items addressed. The test items completed either caused no ignition of the gas mixture, or, after having hardware changes or drilling parameters modified, produced no ignition in repeat testing

  5. Digface characterization test plan (remote testing)

    International Nuclear Information System (INIS)

    The objective of the Digface Characterization (DFC) Remote Testing project is to remotely deploy a sensor head (Mini-Lab) across a digface to determine if it can characterize the contents below the surface. The purpose of this project is to provide a robotics technology that allows removal of workers from hazards, increases speed of operations, and reduces life cycle costs compared to alternate methods and technologies. The Buried Waste Integrated Demonstration (BWID) is funding the demonstration, testing, and evaluation of DFC. This document describes the test plan for the DFC remote deployment demonstration for the BWID. The purposes of the test plan are to establish test parameters so that the demonstration results are deemed useful and usable and perform the demonstration in a safe manner and within all regulatory requirements

  6. Integrated Test and Evaluation Flight Test 3 Flight Test Plan

    Science.gov (United States)

    Marston, Michael Lawrence

    2015-01-01

    The desire and ability to fly Unmanned Aircraft Systems (UAS) in the National Airspace System (NAS) is of increasing urgency. The application of unmanned aircraft to perform national security, defense, scientific, and emergency management are driving the critical need for less restrictive access by UAS to the NAS. UAS represent a new capability that will provide a variety of services in the government (public) and commercial (civil) aviation sectors. The growth of this potential industry has not yet been realized due to the lack of a common understanding of what is required to safely operate UAS in the NAS. NASA's UAS Integration into the NAS Project is conducting research in the areas of Separation Assurance/Sense and Avoid Interoperability, Human Systems Integration (HSI), and Communication to support reducing the barriers of UAS access to the NAS. This research is broken into two research themes namely, UAS Integration and Test Infrastructure. UAS Integration focuses on airspace integration procedures and performance standards to enable UAS integration in the air transportation system, covering Sense and Avoid (SAA) performance standards, command and control performance standards, and human systems integration. The focus of Test Infrastructure is to enable development and validation of airspace integration procedures and performance standards, including the integrated test and evaluation. In support of the integrated test and evaluation efforts, the Project will develop an adaptable, scalable, and schedulable relevant test environment capable of evaluating concepts and technologies for unmanned aircraft systems to safely operate in the NAS. To accomplish this task, the Project will conduct a series of Human-in-the-Loop and Flight Test activities that integrate key concepts, technologies and/or procedures in a relevant air traffic environment. Each of the integrated events will build on the technical achievements, fidelity and complexity of the previous tests and

  7. Load testing circuit

    DEFF Research Database (Denmark)

    2009-01-01

    A load testing circuit a circuit tests the load impedance of a load connected to an amplifier. The load impedance includes a first terminal and a second terminal, the load testing circuit comprising a signal generator providing a test signal of a defined bandwidth to the first terminal of the load...

  8. Nationale test i naturfag

    DEFF Research Database (Denmark)

    Andreasen, Karen Egedal; Jensen, Lars Bang

    2015-01-01

    Kapitlet rummer en analyse og diskussion af test inden for naturfagsområdet og de fagforståelser de afspejler med fokus på de nationale test.......Kapitlet rummer en analyse og diskussion af test inden for naturfagsområdet og de fagforståelser de afspejler med fokus på de nationale test....

  9. Color vision test

    Science.gov (United States)

    Eye test -- color; Vision test -- color; Ishihara color vision test ... lighting. The health care provider will explain the test to you. You will be shown several cards with colored dot patterns. These cards are called Ishihara plates. In the patterns, some of the dots ...

  10. Irradiation effects test series, test IE-5. Test results report

    International Nuclear Information System (INIS)

    Test IE-5, conducted in the Power Burst Facility at the Idaho National Engineering Laboratory, employed three 0.97-m long pressurized water reactor type fuel rods, fabricated from previously irradiated zircaloy-4 cladding and one similar rod fabricated from unirradiated cladding. The objectives of the test were to evaluate the influence of simulated fission products, cladding irradiation damage, and fuel rod internal pressure on pellet-cladding interaction during a power ramp and on fuel rod behavior during film boiling operation. The four rods were subjected to a preconditioning period, a power ramp to an average fuel rod peak power of 65 kW/m, and steady state operation for one hour at a coolant mass flux of 4880 kg/s-m2 for each rod. After a flow reduction to 1800 kg/s-m2, film boiling occurred on one rod. Additional flow reductions to 970 kg/s-m2 produced film boiling on the three remaining fuel rods. Maximum time in film boiling was 80s. The rod having the highest initial internal pressure (8.3 MPa) failed 10s after the onset of film boiling. A second rod failed about 90s after reactor shutdown. The report contains a description of the experiment, the test conduct, test results, and results from the preliminary postirradiation examination. Calculations using a transient fuel rod behavior code are compared with the test results

  11. Flight Test Engineering

    Science.gov (United States)

    Pavlock, Kate Maureen

    2013-01-01

    Although the scope of flight test engineering efforts may vary among organizations, all point to a common theme: flight test engineering is an interdisciplinary effort to test an asset in its operational flight environment. Upfront planning where design, implementation, and test efforts are clearly aligned with the flight test objective are keys to success. This chapter provides a top level perspective of flight test engineering for the non-expert. Additional research and reading on the topic is encouraged to develop a deeper understanding of specific considerations involved in each phase of flight test engineering.

  12. ITER test programme

    International Nuclear Information System (INIS)

    ITER has been designed to operate in two phases. The first phase which lasts for 6 years, is devoted to machine checkout and physics testing. The second phase lasts for 8 years and is devoted primarily to technology testing. This report describes the technology test program development for ITER, the ancillary equipment outside the torus necessary to support the test modules, the international collaboration aspects of conducting the test program on ITER, the requirements on the machine major parameters and the R and D program required to develop the test modules for testing in ITER. 15 refs, figs and tabs

  13. Numeracy Tests For Dummies

    CERN Document Server

    Beveridge, Colin

    2012-01-01

    The easy way to get practice and excel at numeracy tests Whether you're looking for a new job, applying to certain university courses, or attempting to join the military, you're increasingly likely to face a numeracy test as part of the screening process. And the only way to prepare for a numeracy test is practise. Numeracy Tests For Dummies is an accessible one-stop guide to pass these test. Featuring expert advice, instruction, review, and plenty of practise, Numeracy Tests For Dummies will help you succeed. Numeracy Tests For Dummies contains instruction and revision on:Basic mathematical k

  14. Dtest Testing Software

    Science.gov (United States)

    Jain, Abhinandan; Cameron, Jonathan M.; Myint, Steven

    2013-01-01

    This software runs a suite of arbitrary software tests spanning various software languages and types of tests (unit level, system level, or file comparison tests). The dtest utility can be set to automate periodic testing of large suites of software, as well as running individual tests. It supports distributing multiple tests over multiple CPU cores, if available. The dtest tool is a utility program (written in Python) that scans through a directory (and its subdirectories) and finds all directories that match a certain pattern and then executes any tests in that directory as described in simple configuration files.

  15. Pancreatic exocrine function testing

    International Nuclear Information System (INIS)

    It is important to understand which pancreatic function tests are available and how to interpret them when evaluating patients with malabsorption. Available direct tests are the secretin stimulation test, the Lundh test meal, and measurement of serum or fecal enzymes. Indirect tests assess pancreatic exocrine function by measuring the effect of pancreatic secretion on various nutrients. These include triglycerides labeled with carbon 14, cobalamin labeled with cobalt 57 and cobalt 58, and para-aminobenzoic acid bound to a dipeptide. Of all these tests the secretin stimulation test is the most accurate and reliable if done by experienced personnel. However, the indirect tests are simpler to do and appear to be comparable to the secretin test at detecting pancreatic exocrine insufficiency. These indirect tests are becoming clinically available and clinicians should familiarize themselves with the strengths and weaknesses of each

  16. Grimsel test site. Overview and test programs

    International Nuclear Information System (INIS)

    Knowledge of the host rock and surrounding rock strata is of fundamental importance for concepts which provide for final disposal of radioactive waste in geological formations. Taking the studies in the Stripa Rock Laboratory into account, the objectives of the Grimsel Test Site were defined as follows: checking the applicability of foreign research results to geological conditions in Switzerland; carrying out specific experiments which are necessary in the context of the Nagra disposal concepts; acquisition of know-how in planning, implementation and interpretation of underground tests in different experimental areas; acquisition of practical experience in development, testing and use of experimental apparatus and measurement methods. At Grimsel, experiments are to be carried out in the following fields: excavation tests; migration; rock stress measurements; neo-tectonics; geophysics; heat-induced processes; hydrogeology; laboratory experiments. Various tests are already under way. The Grimsel Test Site was established between April 1983 and May 1984. It lies at a depth of 450 m under the Juchlistock and is reached by an access tunnel. The Test Site is operated by Nagra. The experiments are carried out by Nagra and the following two German research establishments: the 'Bundesanstalt fuer Geowissenschaften und Rohstoffe (BGR)' and the 'Gesellschaft fuer Strahlen- und Umweltforschung (GSF)', both under the auspices of the German 'Bundesministerium fuer Forschung und Technologie (BMFT)'. (author)

  17. RT Level Test Scheduling

    OpenAIRE

    J. Blatný; Z. Kotásek; J. Hlavička

    2012-01-01

    The paper describes a new model of exploiting parallelism in testing of VLSI circuits. A circuit at the register transfer level is denoted as an RTL circuit. The model utilizes the concept of TACG (Test Application Conflict Graph). For the testing process the resource utilization model is defined and used for the TACG construction.  Different conflicts that must be taken into account during an RTL circuit test scheduling are presented. The problem of concurrent test application is transf...

  18. POWER CONSCIOUS TESTING

    OpenAIRE

    BONHOMME Y.; Girard, P.; LANDRAULT C.; PRAVOSSOUDOVITCH S.

    2003-01-01

    Test power relates to the power consumed during test of integrated circuits or embedded cores. Test power is now a big concern in large System-on-Chip designs. In this paper, we propose to shortly review the state-of-the-art in this domain. We first survey the recent approaches proposed for minimizing test power. Next, we propose some interesting directions for the development of new low power testing techniques by enumerating the relevant criteria that have to be satisfied.

  19. Pancreatic Exocrine Function Testing

    OpenAIRE

    Goff, John S.

    1982-01-01

    It is important to understand which pancreatic function tests are available and how to interpret them when evaluating patients with malabsorption. Available direct tests are the secretin stimulation test, the Lundh test meal, and measurement of serum or fecal enzymes. Indirect tests assess pancreatic exocrine function by measuring the effect of pancreatic secretion on various nutrients. These include triglycerides labeled with carbon 14, cobalamin labeled with cobalt 57 and cobalt 58, and par...

  20. Irradiation Effects Test Series: Test IE-3. Test results report

    International Nuclear Information System (INIS)

    The objectives of the test reported were to: (a) determine the behavior of irradiated fuel rods subjected to a rapid power increase during which the possibility of a pellet-cladding mechanical interaction failure is enhanced and (b) determine the behavior of these fuel rods during film boiling following this rapid power increase. Test IE-3 used four 0.97-m long pressurized water reactor type fuel rods fabricated from previously irradiated fuel. The fuel rods were subjected to a preconditioning period, followed by a power ramp to 69 kW/m at a coolant mass flux of 4920 kg/s-m2. After a flow reduction to 2120 kg/s-m2, film boiling occurred on the fuel rods. One rod failed approximately 45 seconds after the reactor was shut down as a result of cladding embrittlement due to extensive cladding oxidation. Data are presented on the behavior of these irradiated fuel rods during steady-state operation, the power ramp, and film boiling operation. The effects of a power ramp and power ramp rates on pellet-cladding interaction are discussed. Test data are compared with FRAP-T3 computer model calculations and data from a previous Irradiation Effects test in which four irradiated fuel rods of a similar design were tested. Test IE-3 results indicate that the irradiated state of the fuel rods did not significantly affect fuel rod behavior during normal, abnormal (power ramp of 20 kW/m per minute), and accident (film boiling) conditions