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Sample records for alveolar ridge preservation

  1. Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft

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    Andreas O. Parashis

    2014-01-01

    Full Text Available Alveolar ridge preservation (ARP has been shown to prevent postextraction bone loss. The aim of this report is to highlight the clinical, radiographic, and histological outcomes following use of a bilayer xenogeneic collagen matrix (XCM in combination with freeze-dried bone allograft (FDBA for ARP. Nine patients were treated after extraction of 18 teeth. Following minimal flap elevation and atraumatic extraction, sockets were filled with FDBA. The XCM was adapted to cover the defect and 2-3 mm of adjacent bone and flaps were repositioned. Healing was uneventful in all cases, the XCM remained in place, and any matrix exposure was devoid of further complications. Exposed matrix portions were slowly vascularized and replaced by mature keratinized tissue within 2-3 months. Radiographic and clinical assessment indicated adequate volume of bone for implant placement, with all planned implants placed in acceptable positions. When fixed partial dentures were placed, restorations fulfilled aesthetic demands without requiring further augmentation procedures. Histological and immunohistochemical analysis from 9 sites (4 patients indicated normal mucosa with complete incorporation of the matrix and absence of inflammatory response. The XCM + FDBA combination resulted in minimal complications and desirable soft and hard tissue therapeutic outcomes, suggesting the feasibility of this approach for ARP.

  2. Effect of alveolar ridge preservation after tooth extraction: a systematic review and meta-analysis.

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    Avila-Ortiz, G; Elangovan, S; Kramer, K W O; Blanchette, D; Dawson, D V

    2014-10-01

    Alveolar ridge preservation strategies are indicated to minimize the loss of ridge volume that typically follows tooth extraction. The aim of this systematic review was to determine the effect that socket filling with a bone grafting material has on the prevention of postextraction alveolar ridge volume loss as compared with tooth extraction alone in nonmolar teeth. Five electronic databases were searched to identify randomized clinical trials that fulfilled the eligibility criteria. Literature screening and article selection were conducted by 3 independent reviewers, while data extraction was performed by 2 independent reviewers. Outcome measures were mean horizontal ridge changes (buccolingual) and vertical ridge changes (midbuccal, midlingual, mesial, and distal). The influence of several variables of interest (i.e., flap elevation, membrane usage, and type of bone substitute employed) on the outcomes of ridge preservation therapy was explored via subgroup analyses. We found that alveolar ridge preservation is effective in limiting physiologic ridge reduction as compared with tooth extraction alone. The clinical magnitude of the effect was 1.89 mm (95% confidence interval [CI]: 1.41, 2.36; p < .001) in terms of buccolingual width, 2.07 mm (95% CI: 1.03, 3.12; p < .001) for midbuccal height, 1.18 mm (95% CI: 0.17, 2.19; p = .022) for midlingual height, 0.48 mm (95% CI: 0.18, 0.79; p = .002) for mesial height, and 0.24 mm (95% CI: -0.05, 0.53; p = .102) for distal height changes. Subgroup analyses revealed that flap elevation, the usage of a membrane, and the application of a xenograft or an allograft are associated with superior outcomes, particularly on midbuccal and midlingual height preservation.

  3. A comparison of different compressive forces on graft materials during alveolar ridge preservation

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    2017-01-01

    Purpose Following tooth extraction, alveolar ridge preservation (ARP) can maintain the dimensions of ridge height and width. Although previous studies have demonstrated the effects of ARP, few if any studies have investigated the compressive force applied during grafting. The aim of this study was to determine the effects of different compressive forces on the graft materials during ARP. Methods After tooth extraction, sockets were filled with deproteinized bovine bone mineral with 10% porcine collagen and covered by a resorbable collagen membrane in a double-layered fashion. The graft materials were compressed using a force of 5 N in the test group (n=12) and a force of 30 N in the control group (n=12). A hidden X suture was performed to secure the graft without primary closure. Cone-beam computed tomography (CBCT) was performed immediately after grafting and 4 months later, just before implant surgery. Tissue samples were retrieved using a trephine bur from the grafted sites during implant surgery for histologic and histomorphometric evaluations. Periotest values (PTVs) were measured to assess the initial stability of the dental implants. Results Four patients dropped out from the control group and 20 patients finished the study. Both groups healed without any complications. The CBCT measurements showed that the ridge volume was comparably preserved vertically and horizontally in both groups (P>0.05). Histomorphometric analysis demonstrated that the ratio of new bone formation was significantly greater in the test group (P0.05). Conclusions The application of a greater compressive force on biomaterials during ARP significantly enhanced new bone formation while preserving the horizontal and vertical dimensions of the alveolar ridge. Further studies are required to identity the optimal compressive force for ARP. PMID:28261524

  4. The hidden X suture: a technical note on a novel suture technique for alveolar ridge preservation

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    2016-01-01

    Purpose The present study investigated the impact of 2 different suture techniques, the conventional crossed mattress suture (X suture) and the novel hidden X suture, for alveolar ridge preservation (ARP) with an open healing approach. Methods This study was a prospective randomized controlled clinical trial. Fourteen patients requiring extraction of the maxillary or mandibular posterior teeth were enrolled and allocated into 2 groups. After extraction, demineralized bovine bone matrix mixed with 10% collagen (DBBM-C) was grafted and the socket was covered by porcine collagen membrane in a double-layer fashion. No attempt to obtain primary closure was made. The hidden X suture and conventional X suture techniques were performed in the test and control groups, respectively. Cone-beam computed tomographic (CBCT) images were taken immediately after the graft procedure and before implant surgery 4 months later. Additionally, the change in the mucogingival junction (MGJ) position was measured and was compared after extraction, after suturing, and 4 months after the operation. Results All sites healed without any complications. Clinical evaluations showed that the MGJ line shifted to the lingual side immediately after the application of the X suture by 1.56±0.90 mm in the control group, while the application of the hidden X suture rather pushed the MGJ line slightly to the buccal side by 0.25±0.66 mm. It was demonstrated that the amount of keratinized tissue (KT) preserved on the buccal side was significantly greater in the hidden X suture group 4 months after the procedure (Pclinical and radiographic verification of the efficacy of the hidden X suture in preserving the width of KT and the dimensions of the alveolar ridge after ARP. PMID:28050319

  5. Comparison of alveolar ridge preservation method using three dimensional micro-computed tomographic analysis and two dimensional histometric evaluation

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    Park, Young Seok; Kim, Sung Tae; Oh, Seung Hee; Park, Hee Jung; Lee, Sophia; Kim, Taeil; Lee, Young Kyu; Heo, Min Suk [School of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    2014-06-15

    This study evaluated the efficacy of alveolar ridge preservation methods with and without primary wound closure and the relationship between histometric and micro-computed tomographic (CT) data. Porcine hydroxyapatite with polytetrafluoroethylene membrane was implanted into a canine extraction socket. The density of the total mineralized tissue, remaining hydroxyapatite, and new bone was analyzed by histometry and micro-CT. The statistical association between these methods was evaluated. Histometry and micro-CT showed that the group which underwent alveolar preservation without primary wound closure had significantly higher new bone density than the group with primary wound closure (P<0.05). However, there was no significant association between the data from histometry and micro-CT analysis. These results suggest that alveolar ridge preservation without primary wound closure enhanced new bone formation more effectively than that with primary wound closure. Further investigation is needed with respect to the comparison of histometry and micro-CT analysis.

  6. Alveolar ridge preservation using autogenous tooth graft versus beta-tricalcium phosphate alloplast: A randomized, controlled, prospective, clinical pilot study

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    Chaitanya Pradeep Joshi

    2016-01-01

    Full Text Available Background: A randomized, prospective clinical, radiographical, and histological study was conducted to evaluate healing after alveolar ridge preservation technique using two different graft materials, namely, a novel autogenous graft material i. e., autogenous tooth graft (ATG and beta-tricalcium phosphate (β-TCP alloplast. Materials and Methods: Fifteen patients undergoing extraction of at least three teeth were selected. Atraumatic extractions were performed. Of the three extraction sockets, one was grafted with ATG, other with β-TCP, and the third was left ungrafted. Cone-beam computed tomography scans were taken immediately after grafting and 4 months postoperatively to check the changes in alveolar crest height and width at all the sites. Three patients in whom implant placement was done after complete healing; bone samples were harvested using a 3 mm diameter trephine during osteotomy preparation from both the ridge preserved sites and studied histologically. Results: There was a statistically significant difference when the changes in width and height of alveolar crest were compared within all the three groups (P < 0.05. Among three sites, ATG-grafted sites showed the most superior results with a minimal reduction in alveolar crest height and width. Histological analysis also showed the same trend with more new bone formation at ATG-grafted sites as compared to β-TCP-grafted sites. Conclusion: Postextraction, ridge preservation leads to more predictable maintenance of alveolar ridge height and width. ATG as compared to β-TCP provided superior results. Based on this, we conclude that ATG material can serve as a better alternative to conventional bone graft materials.

  7. A randomized controlled evaluation of alveolar ridge preservation following tooth extraction using deproteinized bovine bone mineral and demineralized freeze-dried bone allograft

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    Rokhsareh Sadeghi

    2016-01-01

    Conclusion: Based on the findings of this study, both materials have positive effect on alveolar ridge preservation after tooth extraction, but there was more new bone formation and less residual graft particles in DFDBA group than in DBBM group.

  8. Influence of preservation of the alveolar ridge on delayed implants after extraction of teeth with different defects in the buccal bone.

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    Pang, Chaoyuan; Ding, Yuxiang; Hu, Kaijin; Zhou, Hongzhi; Qin, Ruifeng; Hou, Rui

    2016-02-01

    Our aim was to evaluate the influence of preservation of the alveolar ridge on delayed implants with different defects in the buccal bone. We enrolled 60 patients who had one posterior mandibular tooth extracted. Cone-beam computed tomography (CT) was used to measure the buccal bone defects in the alveolar ridge before the tooth was extracted (level A=3 to 5 mm, and level B=more than 5 mm). After the tooth had been extracted, the socket either had the alveolar ridge preserved (trial group) or it was left to heal spontaneously (control group). The changes in the dimensions of the alveolar ridge from preoperatively to 6 months postoperatively were evaluated by cone-beam CT. Suitable implants were inserted 6 months later, and their length and diameter recorded. The implant stability quotient was evaluated for the following 3 months. The dimensions of the bone in the alveolar ridge in the trial group were significantly less than those in the control groups in both levels. Fifty-seven patients required implants (except 3 in level B in the control group). There were more longer and wider implants in the trial group than in the control group in Level B. 3 months after implantation, there were no significant differences in implant stability quotients between the groups, though in the control group, Level B, the mean (SD) value was 69.50 (1.00) while in the other groups values were all above 70 at 3 months. We conclude that when the defect in the buccal bone was more than 5mm, the alveolar ridge preservation demonstrated a remarkable effect in preserving the alveolar ridge dimension and delayed implantation.

  9. Vertical Root Fracture: Preservation of the Alveolar Ridge Using Immediate Implants

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    Edmar de Oliveira Oya

    2014-01-01

    Full Text Available Teeth with vertical root fracture (VRF have complete or incomplete fractures that begin in the root and extend toward the occlusal surface. The most frequent causes of VRF originate from physical trauma, occlusal prematurity, inadequate endodontic treatment, and iatrogenic causes. Diagnose is difficult and delay can cause stomatognathic system problem. The purpose of this case report was to evaluate immediate implant placement after extraction of teeth with vertical root fracture. For the 1st case, the VRF in 1st left lower molar was confirmed during surgical flap and at the same time, the tooth was removed and immediate implant was placed. For the 2nd case, the VRF 1st left lower molar was confirmed during endodontic access and at the same appointment, the tooth was removed and the immediate implant is placed. Several studies have shown that immediate implants have similar success rates when compared with late implants. Consider that this approach is a safe procedure with favorable prognosis. In cases of VRF, the main factor to be considered is the presence of adequate bone support and immediate implants can preserve the vertical bone height, adding the fact that good patient compliance reduces the number of surgical interventions and promotes the functionality of stomatognathic system.

  10. A preliminary study of local administration of dexamethasone after tooth extraction: Better preservation of residual alveolar ridge?

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    Poštić Srđan D.

    2014-01-01

    Full Text Available Background/Aim. It is important that the height of the edentulous alveolar ridge after tooth extraction remains at a reasonable acceptable level for as long as possible. The aim of this study was to report preliminary results of the clinical effect of local oral submucous administration of dexamethasone after tooth extractions in order to prepare alveolar supporting tissues for acceptance of removable dentures. Methods. In a total of 15 patients (11 partially and 4 completely edentulous the quantity of 0.25 mL to 0.5 mL of dexamethasone was injected bucally and orally in the region of the tooth socket after complicated extractions. Results. Healing of extraction wounds was uneventful in all the patients, without pain or local inflammation. Conclusion. Dexamethasone can be locally applied to oral tissues to prevent post-extraction inflammation and extensive resorption of the residual alveolar ridge. The obtained results are promising for patients undergoing classic prosthodontic rehabilitation soon after tooth extraction, demonstrating that there are no adverse effects after local oral corticosteroids administration. [Projekat Ministarstva nauke Republike Srbije, br. 175021

  11. A new method to standardize CBCT for quantitative evaluation of alveolar ridge preservation in the mandible: a case report and review of the literature.

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    Xia, Yang; Xie, Lizhe; Zhou, Yi; Song, Tianxi; Zhang, Feimin; Gu, Ning

    2015-12-01

    Cone-beam computerized tomography (CBCT) is an effective technique for assessment of changes to the alveolar ridge (AR). However, its accuracy and reliability could be improved by standardization of imaging positions to remain unchanged during measurements. In this study, an alveolar ridge preservation procedure was performed on a left third molar (38) socket by filling it with a radiotransparent synthetic bone graft, mineralized collagen (MC). Photographic, X-ray and CBCT images were captured before and 3, 6 and 12 months after surgery. A new method was developed to standardize CBCT for quantitative evaluation. Obtained CBCT images showed good comparability. The post-extraction alveolar width and height were both over 95% of the original values, but some resorption of the lingual bone wall (>50%) and inter-crestal bone (>30%). It is concluded that an effective positional standardization method was developed for CBCT assessment of AR dimensional changes in the posterior mandible. The use of MC in combination with a collagen membrane improved dimensional preservation of the AR.

  12. Preservation of ridge dimensions following grafting with coral granules of 48 post-traumatic and post-extraction dento-alveolar defects.

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    Sàndor, George K B; Kainulainen, Vesa T; Queiroz, J Olavo; Carmichael, Robert P; Oikarinen, Kyösti S

    2003-08-01

    This prospective clinical analysis reports on the use of coral granules in alveolar ridge preservation procedures in a population of young, growing patients. The sample consisted of 21 patients, 12 females and 9 males, with a mean age of 13.6 years. These 21 patients had 48 dento-alveolar defects suitable for augmentation with coral granules, and were followed clinically and radiographically for 3-7 years after augmentation. There were two areas of augmentation: 17 defects in the anterior maxilla resulted from traumatic tooth loss, and 31 defects in the posterior maxilla and mandible resulted from the extraction of ankylosed retained primary molars with no permanent succedaneous teeth. Between 1-2 ml of coral granules were implanted into the alveolar bone defects left by the extraction of teeth in both the areas. This was in order to preserve the remaining edentulous ridge from further alveolar ridge resorption. The goal of the procedure was to preserve the alveolus so that in the future, a dental implant could be placed to replace the missing tooth, after jaw growth had stopped, without the need for a bone graft. The coral granules appeared to be totally replaced by the host bone on follow-up clinical and radiographic examinations. The two areas of the jaws behaved quite differently. In the anterior maxilla, where tooth loss was secondary to trauma, the coral granules restored the alveolar ridges temporarily. However, over the years of follow-up in this study, the coral granules failed to provide sufficient bone to support the placement of a dental implant without using a bone graft in 14 of the 17 defects or 82.4% of sites. In the posterior maxilla and mandible, where tooth loss was due to the elective removal of ankylosed primary molars, 29 of the 31 defects or 93.5% of sites were successful as they were able to support the placement of an osseo-integrated dental implant without the use of a bone graft. The alveolar sparing technique was more successful in

  13. Minimally Invasive Alveolar Ridge Preservation Utilizing an In Situ Hardening β-Tricalcium Phosphate Bone Substitute: A Multicenter Case Series

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    Minas D. Leventis

    2016-01-01

    Full Text Available Ridge preservation measures, which include the filling of extraction sockets with bone substitutes, have been shown to reduce ridge resorption, while methods that do not require primary soft tissue closure minimize patient morbidity and decrease surgical time and cost. In a case series of 10 patients requiring single extraction, in situ hardening beta-tricalcium phosphate (β-TCP granules coated with poly(lactic-co-glycolic acid (PLGA were utilized as a grafting material that does not necessitate primary wound closure. After 4 months, clinical observations revealed excellent soft tissue healing without loss of attached gingiva in all cases. At reentry for implant placement, bone core biopsies were obtained and primary implant stability was measured by final seating torque and resonance frequency analysis. Histological and histomorphometrical analysis revealed pronounced bone regeneration (24.4 ± 7.9% new bone in parallel to the resorption of the grafting material (12.9 ± 7.7% graft material while high levels of primary implant stability were recorded. Within the limits of this case series, the results suggest that β-TCP coated with polylactide can support new bone formation at postextraction sockets, while the properties of the material improve the handling and produce a stable and porous bone substitute scaffold in situ, facilitating the application of noninvasive surgical techniques.

  14. Minimally Invasive Alveolar Ridge Preservation Utilizing an In Situ Hardening β-Tricalcium Phosphate Bone Substitute: A Multicenter Case Series

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    Leventis, Minas D.; Fairbairn, Peter; Kakar, Ashish; Leventis, Angelos D.; Margaritis, Vasileios; Lückerath, Walter; Horowitz, Robert A.; Rao, Bappanadu H.; Lindner, Annette; Nagursky, Heiner

    2016-01-01

    Ridge preservation measures, which include the filling of extraction sockets with bone substitutes, have been shown to reduce ridge resorption, while methods that do not require primary soft tissue closure minimize patient morbidity and decrease surgical time and cost. In a case series of 10 patients requiring single extraction, in situ hardening beta-tricalcium phosphate (β-TCP) granules coated with poly(lactic-co-glycolic acid) (PLGA) were utilized as a grafting material that does not necessitate primary wound closure. After 4 months, clinical observations revealed excellent soft tissue healing without loss of attached gingiva in all cases. At reentry for implant placement, bone core biopsies were obtained and primary implant stability was measured by final seating torque and resonance frequency analysis. Histological and histomorphometrical analysis revealed pronounced bone regeneration (24.4 ± 7.9% new bone) in parallel to the resorption of the grafting material (12.9 ± 7.7% graft material) while high levels of primary implant stability were recorded. Within the limits of this case series, the results suggest that β-TCP coated with polylactide can support new bone formation at postextraction sockets, while the properties of the material improve the handling and produce a stable and porous bone substitute scaffold in situ, facilitating the application of noninvasive surgical techniques. PMID:27190516

  15. Comparative alveolar ridge preservation using allogenous tooth graft versus free-dried bone allograft: A randomized, controlled, prospective, clinical pilot study

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    Chaitanya Pradeep Joshi

    2017-01-01

    Full Text Available Background: For the first time in India, allografts from human extracted teeth were prepared. A randomized, prospective, clinicoradiographical, histological study was conducted to evaluate their efficacy in comparison with freeze-dried bone allograft (FDBA in alveolar ridge preservation. Materials and Methods: Graft preparation: with written consent, teeth were collected from three donors (full mouth extraction cases. Once donors' serums were tested negative for HIV, HBV, HCV, and Venereal disease research laboratory (VDRL, mineralized whole tooth allograft (WTA and dentin allograft (DA were prepared using the standard protocol of Tissue Bank at Tata Memorial Hospital, Mumbai, India. Study Design: In this randomized controlled trial, 15 patients undergoing extraction of at least four teeth were selected. In each patient after atraumatic extractions, one socket was grafted with WTA, second with DA, third with FDBA, and fourth was left ungrafted (control site. All the sites were covered with chorion membrane. To estimate three-dimensional alveolar crest changes, cone beam computed tomography scans were taken immediately after grafting and 4 months postoperatively. Bone biopsies using 3 mm trephine bur were obtained from four patients at the time of implant placement and evaluated histologically. Results: Clinically uneventful healing was observed at all sites. Compared to other sites, WTA and DA consistently showed superior results demonstrating least reduction in alveolar crest height and width which was statistically significant (P < 0.05. Between WTA and DA sites, there was no statistically significant difference. Histological analysis also confirmed more new bone formation at WTA and DA sites. Conclusions: Rather than disposing extracted human teeth as a biomedical waste (common practice, they can be collected from suitable systemically healthy donors. With the help of tissue bank, they can be processed into an allograft, serving as an

  16. Comparative Alveolar Ridge Preservation Using Allogenous Tooth Graft versus Free-dried Bone Allograft: A Randomized, Controlled, Prospective, Clinical Pilot Study.

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    Joshi, Chaitanya Pradeep; D'Lima, Cynthia Bernardo; Samat, Urmila Chandrashekhar; Karde, Prerna Ashok; Patil, Agraja Ganpat; Dani, Nitin Hemchandra

    2017-01-01

    For the first time in India, allografts from human extracted teeth were prepared. A randomized, prospective, clinicoradiographical, histological study was conducted to evaluate their efficacy in comparison with freeze-dried bone allograft (FDBA) in alveolar ridge preservation. Graft preparation: with written consent, teeth were collected from three donors (full mouth extraction cases). Once donors' serums were tested negative for HIV, HBV, HCV, and Venereal disease research laboratory (VDRL), mineralized whole tooth allograft (WTA) and dentin allograft (DA) were prepared using the standard protocol of Tissue Bank at Tata Memorial Hospital, Mumbai, India. In this randomized controlled trial, 15 patients undergoing extraction of at least four teeth were selected. In each patient after atraumatic extractions, one socket was grafted with WTA, second with DA, third with FDBA, and fourth was left ungrafted (control site). All the sites were covered with chorion membrane. To estimate three-dimensional alveolar crest changes, cone beam computed tomography scans were taken immediately after grafting and 4 months postoperatively. Bone biopsies using 3 mm trephine bur were obtained from four patients at the time of implant placement and evaluated histologically. Clinically uneventful healing was observed at all sites. Compared to other sites, WTA and DA consistently showed superior results demonstrating least reduction in alveolar crest height and width which was statistically significant (P < 0.05). Between WTA and DA sites, there was no statistically significant difference. Histological analysis also confirmed more new bone formation at WTA and DA sites. Rather than disposing extracted human teeth as a biomedical waste (common practice), they can be collected from suitable systemically healthy donors. With the help of tissue bank, they can be processed into an allograft, serving as an excellent alternative to conventional allografts.

  17. Study of Alveolar Ridge Site Preservation in Posterior Areas%后牙区牙槽骨位点保存的临床研究

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    王丹宁; 邓春富; 赵宝红; 尚德浩; 张翀

    2012-01-01

    Objective: To evaluate clinical effect on prevention of alveolar bone absorption by using site preservation in posterior areas after extraction. Methods: 58 patients of sick teeth in posterior areas were randomly divided into two groups. Patients in the experimental group were implanted Bio-Oss Collagen immediately in alveolar fossa after extraction, which covered Bio - Gide on the surface. Patients in control group were sutured or hemostasised by oppressing. Two groups were observated the change of alveolar bone density, height and new bone contour by taking radiographs after half a year. Results: Compared with two groups, bone density and new bone contour of the experimental group was significantly better than the control group after half a year, while absorption of vertical bone were significantly lower than that of control group. There was statistically significant difference between two groups. Conclusion: Site preservation technology can maintain bone of alveolar ridge perfectly, and reduce bone defect caused by extraction, which contributes to provide an ideal condition for later implanting.%目的:评价后牙区拔牙后应用位点保存技术预防牙槽骨吸收的临床疗效.方法:58例后牙区患牙的患者随机分为2组,实验组患者拔牙后牙槽窝内即刻植入Bio-Oss Collagen,表面覆盖Bio Gide膜,对照组拔牙后缝合或压迫止血,半年后拍摄X线片观察牙槽骨密度、高度、新骨轮廓的变化.结果:2组比较,术后半年实验组骨密度、新骨轮廓明显优于对照组,垂直向骨吸收量明显小于对照组,两组之间具有统计学差异.结论:位点保存技术可以很好的维持牙槽嵴骨量,减少因拔牙造成的骨缺损,为后期的种植提供良好的位点条件.

  18. Comparative evaluation of a biomimic collagen/hydroxyapatite/β-tricaleium phosphate scaffold in alveolar ridge preservation with Bio-Oss Collagen

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    Wang, Tong; Li, Qing; Zhang, Gui-feng; Zhou, Gang; Yu, Xin; Zhang, Jing; Wang, Xiu-mei; Tang, Zhi-hui

    2016-06-01

    Bone scaffolds are critical in current implant and periodontal regeneration approaches. In this study, we prepared a novel composite type-I collagen and hydroxyapatite (HA)/β-tricaleium phosphate (TCP) scaffold (CHTS) by incorporating type-I collagen and bovine calcined bone granules, prepared as a mixture of 50% HA and 50% TCP, by freeze drying. We then characterized the CHTS and determined its cytotoxic effects. Additionally, ridge preservation experiments were carried out to evaluate the clinical effects of the CHTS. The results demonstrated that the composite scaffolds had good surface morphology and no cytotoxicity. Additionally, an in vivo experiment in an animal model showed that the CHTS performed equally as well as Bio-Oss Collagen, a widely used bone graft in ridge preservation. These findings revealed that the CHTS, which contained natural constituents of bone, could be used as a scaffold for bone regeneration and clinical use.

  19. Research prowess on reduction of bone resorption through alveolar ridge preservation after tooth extraction%应用牙槽窝保存技术减少拔牙后骨吸收的研究进展

    Institute of Scientific and Technical Information of China (English)

    张勇

    2011-01-01

    口腔种植作为一种缺失牙的修复方式已经被临床广泛地接受,然而,成功的种植修复需要有足够的牙槽骨骨量和良好的牙槽嵴外形.患者的牙齿拔除后,骨吸收会造成牙槽嵴体积和外形的变化.若这种变化在临床上较为明显,可以对种植修复或传统修复造成困难.牙槽嵴保存技术则可以使拔牙后的牙槽嵴吸收最小化,可以保持足够的牙槽骨量,从而有助于获得理想的美学和功能修复.本文对牙槽窝保存技术、微创拔牙技术、拔牙后的牙槽窝愈合模式以及骨移植材料和屏障膜的使用作一综述.%Implant therapy has become a widely recognized treatment alternative for replacing missing teeth.While successful implant therapy requires sufficient alveolar bone volume and favorable ridge architecture. After tooth extraction, dimensional changes of the alveolar ridge often occur due to bone resorption. These changes are usually clinically significant and can complicate restorations with implant or conventional prostheses. Preservation of alveolar dimension can minimize residual ridge resorption and can be essential to maintain adequate bone volume, thus be crucial to achieve optimal esthetic and functional prosthodontic results. This article reviewed the literature, presents socket preservation techniques, atraumatic tooth extraction, healing pattern of socket after tooth extraction as well as the use of bone grafting materials and barrier membranes.

  20. Improving prosthetic prognosis by connective tissue ridge augmentation of alveolar ridge

    OpenAIRE

    2010-01-01

    The contour of edentulous ridge should be carefully evaluated before a fixed partial denture is undertaken. The ideal ridge height and width allows placement of a natural looking pontic which facilitates maintenance of plaque-free environment. The localized alveolar ridge defect refers to the volumetric deficit of the limited extent of bone and soft tissue within the alveolar process. Such type of ridge defects can be corrected by surgical ridge augmentation that can be accomplished by the ad...

  1. Alveolar ridge rehabilitation to increase full denture retention and stability

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    Mefina Kuntjoro

    2010-12-01

    Full Text Available Background: Atrophic mandibular alveolar ridge generally complicates prostetic restoration expecially full denture. Low residual alveolar ridge and basal seat can cause unstable denture, permanent ulcer, pain, neuralgia, and mastication difficulty. Pre-proshetic surgery is needed to improve denture retention and stability. Augmentation is a major surgery to increase vertical height of the atrophic mandible while vestibuloplasty is aimed to increase the denture bearing area. Purpose: The augmentation and vestibuloplasty was aimed to provide stability and retentive denture atrophic mandibular alveolar ridge. Case: A 65 years old woman patient complained about uncomfortable denture. Clinical evaluate showed flat ridge in the anterior mandible, flabby tissue and candidiasis, while residual ridge height was classified into class IV. Case management: Augmentation using autograph was conducted as the mandible vertical height is less than 15 mm. Autograph was used to achieve better bone quantity and quality. Separated alveolar ridge was conducted from left to right canine region and was elevated 0.5 mm from the previous position to get new ridge in the anterior region. The separated alveolar ridge was fixated by using T-plate and ligature wire. Three months after augmentation fixation appliances was removed vestibuloplasty was performed to increase denture bearing area that can make a stable and retentive denture. Conclusion: Augmentation and vestibuloplasty can improve flat ridge to become prominent.Latar belakang: Ridge mandibula yang atrofi pada umumnya mempersulit pembuatan restorasi prostetik terutama gigi tiruan lengkap (GTL. Residual alveolar ridge dan basal seat yang rendah menyebabkan gigi tiruan menjadi tidak stabil, menimbulkan ulser permanen, nyeri, neuralgia, dan kesulitan mengunyah. Tujuan: Augmentasi dan vestibuloplasti pada ridge mandibula yang atrofi dilakukan untuk menciptakan gigi tiruan yang stabil dan retentive. Kasus: Pasien wanita

  2. Effect of immediate implantation of beta-tricalcium phosphate scaffold on preserving the alveolar ridge%β-磷酸三钙支架材料即刻植入对保存剩余牙槽嵴的影响

    Institute of Scientific and Technical Information of China (English)

    胡杨; 马莹; 何惠宇

    2011-01-01

    BACKGROUND:The bone materials were immediately implanted into dental alveoli after tooth extraction, such as deproteinized small cattle bone, hydroxyapatite and hard tissue substitutes, human demineralized freeze-dried bone, etc. These materials could prevent or delay the rapid, sustained absorption of alveolar ridge after tooth extraction.OBJECTIVE:To observe the effect of immediate implantation of β-tricalcium phosphate (β-TCP) on preserving the residual alveolar.METHODS:The bilateral and mandibular central incisors of 18 New Zealand White rabbits were extracted, and β-TCP was implanted immediately into dental alveoli on one side as the experimental group, while the other side without implantion as control group. The length, width, and height of residual ridge was measured at 4, 8, 12 weeks after operation. The histopathological changes of the healing procedure of alveolar crest in the surgical region were observed by toluidine blue staining. Changes of bone mineral density of alveolar crest in the surgical region were observed by X-ray. The interface between β-TCP and trabecular bone of teeth extraction were observed by scanning electron microscopy.RESULTS AND CONCLUSION:The height, width, and length of alveolar ridge in experimental group were higher than that in control group (P < 0.05) at 8, 12 weeks after operation. With the prolonged time, osteoblasts can be seen scattered in the experimental group, new trabecular bone was gradually increased and vascular network became more and more intensive. New bone and β-TCP combined with increasingly close, and β-TCP continued degradation, new bone tissue was formed in the interface between β-TCP and the alveolar bone. It suggested that β-TCP has good bone conduction properties and biological compatibility. It was implanted immediately after tooth extraction, which could effectively preserve the anatomic form of residual alveolar ridge, and prevent further absorption of alveolar ridge.%背景:拔牙后在

  3. Alveolar ridge augmentation by osteoinductive materials in goats

    DEFF Research Database (Denmark)

    Pinholt, E M; Haanaes, H R; Roervik, M

    1992-01-01

    The purpose of the present study was to determine whether alveolar ridge augmentation could be induced in goats. In 12 male goats allogenic, demineralized, and lyophilized dentin or bone was implanted subperiosteally on the buccal sides of the natural edentulous regions of the alveolar process of...

  4. Improving prosthetic prognosis by connective tissue ridge augmentation of alveolar ridge

    Directory of Open Access Journals (Sweden)

    Mishra Niraj

    2010-01-01

    Full Text Available The contour of edentulous ridge should be carefully evaluated before a fixed partial denture is undertaken. The ideal ridge height and width allows placement of a natural looking pontic which facilitates maintenance of plaque-free environment. The localized alveolar ridge defect refers to the volumetric deficit of the limited extent of bone and soft tissue within the alveolar process. Such type of ridge defects can be corrected by surgical ridge augmentation that can be accomplished by the addition of either soft or hard tissues. This article describes a procedure of surgical connective tissue augmentation of a localized deficient alveolar ridge in the maxilla, followed by fixed partial denture, enhancing the esthetics, function and health.

  5. Improving prosthetic prognosis by connective tissue ridge augmentation of alveolar ridge.

    Science.gov (United States)

    Mishra, Niraj; Singh, Balendra P; Rao, Jitendra; Rastogi, Pavitra

    2010-01-01

    The contour of edentulous ridge should be carefully evaluated before a fixed partial denture is undertaken. The ideal ridge height and width allows placement of a natural looking pontic which facilitates maintenance of plaque-free environment. The localized alveolar ridge defect refers to the volumetric deficit of the limited extent of bone and soft tissue within the alveolar process. Such type of ridge defects can be corrected by surgical ridge augmentation that can be accomplished by the addition of either soft or hard tissues. This article describes a procedure of surgical connective tissue augmentation of a localized deficient alveolar ridge in the maxilla, followed by fixed partial denture, enhancing the esthetics, function and health.

  6. Alveolar Ridge Split Technique Using Piezosurgery with Specially Designed Tips

    Science.gov (United States)

    Moro, Alessandro; Foresta, Enrico; Falchi, Marco; De Angelis, Paolo; D'Amato, Giuseppe; Pelo, Sandro

    2017-01-01

    The treatment of patients with atrophic ridge who need prosthetic rehabilitation is a common problem in oral and maxillofacial surgery. Among the various techniques introduced for the expansion of alveolar ridges with a horizontal bone deficit is the alveolar ridge split technique. The aim of this article is to give a description of some new tips that have been specifically designed for the treatment of atrophic ridges with transversal bone deficit. A two-step piezosurgical split technique is also described, based on specific osteotomies of the vestibular cortex and the use of a mandibular ramus graft as interpositional graft. A total of 15 patients were treated with the proposed new tips by our department. All the expanded areas were successful in providing an adequate width and height to insert implants according to the prosthetic plan and the proposed tips allowed obtaining the most from the alveolar ridge split technique and piezosurgery. These tips have made alveolar ridge split technique simple, safe, and effective for the treatment of horizontal and vertical bone defects. Furthermore the proposed piezosurgical split technique allows obtaining horizontal and vertical bone augmentation.

  7. Alveolar Ridge Split Technique Using Piezosurgery with Specially Designed Tips

    Directory of Open Access Journals (Sweden)

    Alessandro Moro

    2017-01-01

    Full Text Available The treatment of patients with atrophic ridge who need prosthetic rehabilitation is a common problem in oral and maxillofacial surgery. Among the various techniques introduced for the expansion of alveolar ridges with a horizontal bone deficit is the alveolar ridge split technique. The aim of this article is to give a description of some new tips that have been specifically designed for the treatment of atrophic ridges with transversal bone deficit. A two-step piezosurgical split technique is also described, based on specific osteotomies of the vestibular cortex and the use of a mandibular ramus graft as interpositional graft. A total of 15 patients were treated with the proposed new tips by our department. All the expanded areas were successful in providing an adequate width and height to insert implants according to the prosthetic plan and the proposed tips allowed obtaining the most from the alveolar ridge split technique and piezosurgery. These tips have made alveolar ridge split technique simple, safe, and effective for the treatment of horizontal and vertical bone defects. Furthermore the proposed piezosurgical split technique allows obtaining horizontal and vertical bone augmentation.

  8. 保存上前牙拔牙窝水平骨量的临床新技术%A novel technique to preserve the alveolar ridge width following tooth extraction in the maxillary frontal area

    Institute of Scientific and Technical Information of China (English)

    蒋析; 林野; 张宇; 邸萍; 陈波; 胡秀莲; 罗佳; 任抒欣; 欧阳思远

    2016-01-01

    Objective:To introduce a novel ridge preservation technique with micro-titanium plate avoiding the use of bone grafting materials,and evaluate the potential horizontal bone preservation effect of this new technique,applied on single maxillary central incisors after tooth extraction for future implant restoration.Methods:Nine patients (six women and three men),mean age (26.0 ±5.7)years(from 1 8 to 34 years)referred to the Department of Oral Implantology,Peking University School and Hospital of Stomotology,were selected and diagnosed with unsalvageable single middle incisor with fine general con-ditions,no signs of acute local inflammation,no ongoing or previous periodontitis,healthy neighboring teeth and intact buccal bone walls.Tooth extraction,delayed implant placement and implant-supported single crown restoration were selected as treatment plan.The teeth were extracted atraumatically with lo-cal anesthesia,followed by a reflection of a minor flap to exposed 2-3 mm of the buccal bone plate.Af-ter that,a micro-titanium plate was trimmed and bended to fit the convexity of the labial bone and fixed by two mini pins with intent to support the labial soft tissue.The flap was then repositioned over the micro titanium plate and secured with two single sutures.No bone grafting materials or releasing incisions were needed.The sockets were left to heal without any intention of primary wound closure.Cone-beam compu-ted tomographic (CBCT)scans were obtained before and four months after tooth extraction.Horizontal ridge widths were measured with CBCT software,and the preservation effects were calculated and recor-ded by the percentage of horizontal ridge alteration.Results:The nine extraction sockets were healed un-eventfully.The average socket width before extraction was (7.51 ±0.48)mm (6.92-7.82 mm).The average alveolar ridge labial-palatal width at the control point of the edentulous area was (6.81 ±0.44) mm (6.04-7.38 mm)4 months after tooth extraction,the mean

  9. Alveolar Ridge Conservation by Early Bone Formation After Tooth Extraction in Rabbits. A Histomorphological Study

    Science.gov (United States)

    Cantín, Mario; Olate, Sergio; Fuentes, Ramón; Vásquez, Bélgica

    2016-01-01

    SUMMARY Alveolar ridge volume loss is an irreversible process. To prevent this physiological event, which typically result in significant local anatomical changes in both the horizontal and the vertical dimension, some strategies are indicated to minimize the loss of ridge volume that typically follows tooth extraction. The purpose of this study was to evaluate if three different bone grafts could promote new bone formation in the alveolar socket following tooth extraction for the alveolar ridge conservation. First mandibular molars of male adults rabbits were extracted and the extraction sockets were randomly treated with three different bone grafts, one xenograft and two alloplastic grafts, and a group that received no treatment (blood clot). The extraction sockets of selected rabbits from each group were evaluated at 4, 6, or 8-week post-extraction. The results indicated that the extraction sockets treated with alloplastic graft (biphasic calcium phosphate) exhibited lamellar bone formation (6.5%) as early as four weeks after the extraction was performed. Moreover, the degree of new bone formation was significantly higher (P<0.05) in the extraction sockets treated with biphasic calcium phosphate at 8-week post-extraction than that in the other study groups. In this study, we demonstrated that the proposed animal model is useful to evaluate the bone formation after tooth extraction and the alveolar ridge conservation is feasible. The new bone formation and alveolar ridge preservation with bone graft after extraction of molar teeth, could result in the maintenance of sufficient bone volume to place an implant in an ideal restorative position without the need for ancillary implant site development procedures. PMID:27840551

  10. Combined soft and hard tissue augmentation for a localized alveolar ridge defect

    OpenAIRE

    2013-01-01

    Ideal alveolar ridge width and height allows placement of a natural appearing pontic, which provides maintenance of a plaque-free environment. The contour of a partially edentulous ridge should be thoroughly evaluated before a fixed partial denture is undertaken. Localized alveolar ridge defect refers to a volumetric deficit of the limited extent of bone and soft-tissue within the alveolar process. These ridge defects can be corrected by hard tissue and/or soft-tissue augmentation. A 30-year-...

  11. Partial Extraction Therapies (PET) Part 1: Maintaining Alveolar Ridge Contour at Pontic and Immediate Implant Sites.

    Science.gov (United States)

    Gluckman, Howard; Salama, Maurice; Du Toit, Jonathan

    2016-01-01

    Buccopalatal collapse of the postextraction ridge is a significant challenge in restorative and implant dentistry. A variety of ridge preservation techniques using tissue and augmentative materials have been proposed in the literature. A slightly different approach is to use the tooth itself. Root submergence has been reported in the literature for more than 4 decades, and it has been demonstrated that the submerged tooth root retains the periodontal tissues and preserves the bone in pontic sites or below dentures to retain the ridge. The socket-shield technique entails preparing a tooth root section simultaneous to immediate implant placement and has demonstrated histologic and clinical results that are highly promising to esthetic implant treatment. The pontic shield technique preserves the alveolar ridge at sites intended for pontic development where the root submergence technique is not possible. The aforementioned techniques collectively may be termed partial extraction therapies (PET), a term newly introduced into the literature and clinical environment. This article is a review of these ridge preservation therapies, providing a classification and a guide to their application.

  12. Alveolar ridge augmentation in rats by Bio-Oss

    DEFF Research Database (Denmark)

    Pinholt, E M; Bang, G; Haanaes, H R

    1991-01-01

    The purpose of the study was to examine if Bio-Oss initiated osteoinduction or osteoconduction when implanted into rats. Sintered and unsintered granules of the anorganic bovine bone Bio-Oss was implanted subperiosteally for alveolar ridge augmentation purposes and heterotopically in the abdominal...... muscles of rats. Light microscopic evaluation revealed no osteoinduction or osteoconduction in connection with sintered or unsintered Bio-Oss. A foreign body reaction was observed around both forms....

  13. Aesthetic enhancement with periodontal plastic procedure in a class 3 alveolar ridge defect

    OpenAIRE

    2012-01-01

    Localised alveolar ridge defect refers to volumetric deficit of the limited extent of bone and soft tissue within the alveolar process. Such type of ridge defects can be corrected by surgical ridge augmentation that can be accomplished by the addition of either soft or hard tissues. The contour of a partially edentulous ridge should be thoroughly evaluated before a fixed partial denture is undertaken. The ideal ridge width and height allows placement of a natural appearing pontic which provid...

  14. Histologic and radiographic evaluation of different bone grafts in ridge preservation procedures

    OpenAIRE

    Barallat Sendagorta, Lucía

    2016-01-01

    The main goal of this PhD project was to better understand how different types of bone grafts behave in ridge preservation procedures. There is clear evidence that, after tooth removal, a healing process takes place in which the blood clot that fills the socket is gradually substituted with new bone. This process is accompanied by a reduction in height and width of the alveolar ridge. These events may result in limited bone availability, which may compromise an adequate implant pl...

  15. The potential of mangosteen (Garcinia mangostana peel extract, combined with demineralized freeze-dried bovine bone xenograft, to reduce ridge resorption and alveolar bone regeneration in preserving the tooth extraction socket

    Directory of Open Access Journals (Sweden)

    Utari Kresnoadi

    2017-01-01

    Conclusion: The induction of MPEs and DFBBX is effective in reducing inflammation, lowering osteoclasts, decreasing alveolar bone resorption, and also increasing BMP2 expression and alveolar bone regeneration.

  16. 不同测量方法评价磨牙拔牙位点保存术后牙槽骨的变化%Evaluation with different measuring methods for the alveolar bone change of ridge preservation in molar sites

    Institute of Scientific and Technical Information of China (English)

    赵丽萍; 詹雅琳; 胡文杰; 徐涛; 危伊萍; 甄敏; 王翠

    2016-01-01

    目的:采用临床直接测量、平行投照根尖片和锥形束CT(cone-beam computed tomography,CBCT)评价存在骨缺损的磨牙拔牙同期位点保存6个月后牙槽骨的变化,并分析不同方法的测量效果。方法:纳入20名患者共23颗因牙周病变拔除的磨牙,牙齿拔除后应用去骨蛋白牛骨基质(deproteinized boving bone mineral,DBBM,Bio-Oss)和可吸收膜(bioabsorbable collagen membrane,Bio-Gide)进行拔牙位点保存术,术中临床直接测量,术后即刻及术后6个月拍摄平行投照根尖片和CBCT,通过上述3种方法测量分析术后6个月牙槽骨高度和宽度的变化并比较测量效果的异同。结果:比较23个拔牙位点的牙槽骨高度在拔牙位点中央、远中中央、颊侧远中3个观察点的术中临床测量与CBCT测量的结果,差异无统计学意义(P>0.05),其他观察点的高度及宽度测量结果差异有统计学意义(P<0.05)。术后6个月接受翻瓣再进入实施种植的10名患者中,拔牙位点中央相应观察点的牙槽骨高度显著增加,临床直接测量和CBCT测量分别增加(6.15±1.73)mm和(6.59±2.53)mm,牙槽骨宽度测量值分别为(8.45±1.18)mm和(8.52±1.27)mm,两种方法测量结果差异无统计学意义(P>0.05);应用平行投照根尖片观察术前和术后6个月拔牙位点中央的牙槽骨高度变化为增加(5.84±4.28)mm,测量数值与另两种方法接近。结论:存在骨缺损的磨牙应用Bio-Oss与Bio-Gide进行拔牙位点保存后,临床直接测量和CBCT测量两种方法对牙槽嵴顶骨高度和宽度变化的评价基本一致。%Objective:To investigate the changes of the vertical height and width of the alveolar bone six months after the alveolar ridge preservation in periodontal compromised molar sites of severe alveolar bone defects with clinical direct measurement

  17. Aesthetic enhancement with periodontal plastic procedure in a class 3 alveolar ridge defect.

    Science.gov (United States)

    Rastogi, Pavitra Kumar

    2012-12-23

    Localised alveolar ridge defect refers to volumetric deficit of the limited extent of bone and soft tissue within the alveolar process. Such type of ridge defects can be corrected by surgical ridge augmentation that can be accomplished by the addition of either soft or hard tissues. The contour of a partially edentulous ridge should be thoroughly evaluated before a fixed partial denture is undertaken. The ideal ridge width and height allows placement of a natural appearing pontic which provides maintenance of a plaque-free environment. This article describes a procedure of surgical ridge augmentation of a localised alveolar ridge defect in the maxilla, followed by fixed partial denture, enhancing the aesthetics, function and health.

  18. The comparision of the outcomes of guide bone regeneration by calcined bovine bone and Bio-Oss graft material in alveolar ridge preservation after tooth extraction%骨引导天然煅烧骨与Bio-Oss用于牙槽嵴保存效果的对比研究

    Institute of Scientific and Technical Information of China (English)

    刘伟; 丁宇翔; 秦瑞峰; 侯锐; 周宏志; 张林林; 胡开进

    2014-01-01

    Objective:To compare the outcomes of guide bone regeneration by calcined bovine bone and Bio-Oss graft material in alveolar ridge preservation after tooth extraction.Methods:280 patients were divided into two groups randomly.Each patient had single tooth extracted.The sockets were filled with calcined bovine bone in 140 patients and Bio-Oss graft in another 140 patients. After shaping,all the sockets were covered with Bio-Gide membrane.Buccal mucoperiosteal flap was released and sutured to close the alveolar sockets.The patients were regularly examined at the 1st,12th and 24th week after surgery.Physical examination and X-ray evaluation were applied to compare the outcomes of the two materials in alveolar ridge preservation.Results:No infection and re-jection occurred.The radiographic results showed the width and height of the alveolar bone were preserved well at the 12th and 24th weeks.No statistically difference was found in the two groups at the 1st and 24th weeks(P>0.05).Conclusion:The two graft ma-terials can effectively preserve alveolar bone after tooth extraction.%目的:对比骨引导天然煅烧骨与Bio-Oss应用于拔牙后牙槽嵴保存的效果。方法:280例患者单颗牙拔除后,随机分为2组,将骨引导天然煅烧骨和Bio-Oss各植入140例拔牙窝中,塑形后均用Bio-Gide生物膜覆盖,颊侧黏骨膜翻瓣、滑行缝合、封闭拔牙创,并在术后第1周、12周、24周复查,拍摄全口曲面断层片及CT,评价2种植骨材料牙槽嵴保存的效果。结果:2组的大体观察均显示出了较好的结果,无感染及排斥反应。12周及24周影像学结果显示2组牙槽嵴的宽度和高度均得到了较好的保存,组间比较无统计学差异(P>0.05)。结论:2种植骨材料均能有效地保存拔牙后牙槽骨的骨量。

  19. Volumetric Changes in Edentulous Alveolar Ridge Sites Utilizing Guided Bone Regeneration and a Custom Titanium Ridge Augmentation Matrix (CTRAM)

    Science.gov (United States)

    2016-06-01

    Milling CBCT Cone Beam Computed Tomography CT Computed Tomography CTRAM Custom Titanium Ridge Augmentation Matrix DMLS Direct Metal Laser Sintering ...could be used by Direct Metal Laser Sintering (DMLS) to create custom titanium mesh to reconstruct a deficient maxillary alveolar anterior ridge. A pre...Sinus Augmentations. Int J Periodont Rest Dent 2005; 25:231-237. Ciocca L, Fantini M, De Crescenzio F, Corinaldesi G, Scotti R. Direct Metal

  20. Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in Minipigs

    Directory of Open Access Journals (Sweden)

    Hanna Tiainen

    2012-01-01

    Full Text Available Despite being considered noncritical size defects, extraction sockets often require the use of bone grafts or bone graft substitutes in order to facilitate a stable implant site with an aesthetically pleasing mucosal architecture and prosthetic reconstruction. In the present study, the effect of novel TiO2 scaffolds on dimensional ridge preservation was evaluated following their placement into surgically modified extraction sockets in the premolar region of minipig mandibles. After six weeks of healing, the scaffolds were wellintegrated in the alveolar bone, and the convex shape of the alveolar crest was preserved. The scaffolds were found to partially preserve the dimensions of the native buccal and lingual bone walls adjacent to the defect site. A tendency towards more pronounced vertical ridge resorption, particularly in the buccal bone wall of the nongrafted alveoli, indicates that the TiO2 scaffold may be used for suppressing the loss of bone that normally follows tooth extraction.

  1. Combined soft and hard tissue augmentation for a localized alveolar ridge defect

    Directory of Open Access Journals (Sweden)

    Ritu Rana

    2013-01-01

    Full Text Available Ideal alveolar ridge width and height allows placement of a natural appearing pontic, which provides maintenance of a plaque-free environment. The contour of a partially edentulous ridge should be thoroughly evaluated before a fixed partial denture is undertaken. Localized alveolar ridge defect refers to a volumetric deficit of the limited extent of bone and soft-tissue within the alveolar process. These ridge defects can be corrected by hard tissue and/or soft-tissue augmentation. A 30-year-old male patient was referred to the Department of Periodontology for correction of Seibert′s Class III ridge defect in the lower anterior region. Granulation tissue/connective tissue present at the base of the defect was removed after elevation of full thickness flap. MucoMatrixX, an animal derived, collagen based soft-tissue graft was sutured to the labial flap and bone graft was placed into the defect. If a soft-tissue graft material could be used to replace the palatal grafts, then all the possible complications associated with donor site would be eliminated and above all periodontal plastic surgery and ridge augmentation would be better accepted by patients.

  2. Combined soft and hard tissue augmentation for a localized alveolar ridge defect.

    Science.gov (United States)

    Rana, Ritu; Ramachandra, Srinivas Sulugodu; Lahori, Manesh; Singhal, Reetika; Jithendra, K D

    2013-10-01

    Ideal alveolar ridge width and height allows placement of a natural appearing pontic, which provides maintenance of a plaque-free environment. The contour of a partially edentulous ridge should be thoroughly evaluated before a fixed partial denture is undertaken. Localized alveolar ridge defect refers to a volumetric deficit of the limited extent of bone and soft-tissue within the alveolar process. These ridge defects can be corrected by hard tissue and/or soft-tissue augmentation. A 30-year-old male patient was referred to the Department of Periodontology for correction of Seibert's Class III ridge defect in the lower anterior region. Granulation tissue/connective tissue present at the base of the defect was removed after elevation of full thickness flap. MucoMatrixX, an animal derived, collagen based soft-tissue graft was sutured to the labial flap and bone graft was placed into the defect. If a soft-tissue graft material could be used to replace the palatal grafts, then all the possible complications associated with donor site would be eliminated and above all periodontal plastic surgery and ridge augmentation would be better accepted by patients.

  3. Alveolar ridge changes in patients congenitally missing mandibular second premolars.

    Science.gov (United States)

    Ostler, M S; Kokich, V G

    1994-02-01

    This study investigated changes in ridge width over time in patients who were congenitally missing mandibular second premolars. Data were obtained from stone casts and radiographs of 35 edentulous sites on 22 patients representing three time periods: (1) before extraction of the primary mandibular second molar, (2) completion of orthodontic treatment, and (3) long-term evaluation. The findings indicate that ridge width decreases 25% within 3 years after primary molar extraction. The rate of decrease diminishes to 4% over the next 3 years. The change in ridge width had a weak association with the age of the patient at the time of the extraction but a small predictive value. No correlation was found between changes in ridge width and height and the time since the extraction or the age of the patient at the time of extraction.

  4. Titanium implant insertion into dog alveolar ridges augmented by allogenic material

    DEFF Research Database (Denmark)

    Pinholt, E M; Haanaes, H R; Donath, K

    1994-01-01

    The purpose of this investigation was to evaluate whether titanium endosseous implants would osseointegrate in dog alveolar ridges augmented by allogenic material. In 8 dogs en bloc resection, including 2 pre-molars, was performed bilaterally in the maxilla and the mandible. After a healing perio...

  5. Chemical, physical, and histologic studies on four commercial apatites used for alveolar ridge augmentation

    DEFF Research Database (Denmark)

    Pinholt, E M; Ruyter, I E; Haanaes, H R

    1992-01-01

    The purpose of this study was to evaluate four commercial apatite products. Subperiosteal alveolar ridge augmentation was performed on the maxilla of rats by implantation of granules of two dense products and of two porous products, and the tissue response was compared with the material character...

  6. Histological Features and Biocompatibility of Bone and Soft Tissue Substitutes in the Atrophic Alveolar Ridge Reconstruction

    Directory of Open Access Journals (Sweden)

    Carlo Maiorana

    2016-01-01

    Full Text Available The reconstruction of the atrophic alveolar ridges for implant placement is today a common procedure in dentistry daily practice. The surgical reconstruction provides for the optimization of the supporting bone for the implants and a restoration of the amount of keratinized gingiva for esthetic and functional reasons. In the past, tissue regeneration has been performed with autogenous bone and free gingival or connective tissue grafts. Nowadays, bone substitutes and specific collagen matrix allow for a complete restoration of the atrophic ridge without invasive harvesting procedures. A maxillary reconstruction of an atrophic ridge by means of tissue substitutes and its histological features are then presented.

  7. Periodontal plastic surgery for management of cleft alveolar ridge: a case report.

    Science.gov (United States)

    Agrawal, Amit A; Yeltiwar, Ramreddy K

    2012-02-01

    Cleft lips, alveoli, and palates are the most common congenital malformations of the head and neck region, all of which often can be managed successfully when presented at a young age. It is a common belief that clefts in the alveolar ridge should be treated with the help of bone grafting materials. This could be the best option when the cleft is to be treated in early age, when the patient is still developing and has high regenerative potential. However, in adults, the literature supports the fact that bone grafting in alveolar clefts has a higher chance for failure. The present case report exemplifies a periodontal plastic surgical procedure involving a combination of connective tissue and free gingival grafting to restore the form and function of a cleft alveolar ridge in an adult patient.

  8. Fabrication and anti-microbial evaluation of drug loaded polylactide space filler intended for ridge preservation following tooth extraction

    Directory of Open Access Journals (Sweden)

    Nebu George Thomas

    2011-01-01

    Full Text Available Background: The preservation or reduction of alveolar ridge resorption following tooth extraction is important in patients especially for those intended for implants at a later stage. One way to achieve this is by using membranes, graft materials, and biodegradable space fillers to prevent alveolar bone resorption and promote regeneration. A major attraction for using biodegradable and biocompatible polymers as space fillers for ridge preservation is their safety profile in comparison to xenograft materials like lyophilized bone and collagen. Materials and Methods: Biocompatible polylactide space fillers were fabricated by fusing porous polylactide particles. The sponges were loaded with drugs by placing them in the respective solutions. Pseudomonas aeruginosa was isolated from a chronic periodontitis patient and in vitro anti-microbial evaluation was done with the drug loaded sponges. Results: Chlorhexidine loaded space filler showed significant anti microbial effect against multiple drug resistant Pseudomonas aeruginosa isolated from a patient with chronic periodontitis. Conclusion: The results of this study indicate that biodegradable drug releasing polylactide space fillers has the potential to be used for ridge preservation following tooth extraction. Release of drugs in the socket may prove useful in preventing development of alveolar osteitis post extraction which can interfere with normal healing of the socket. Synthetic biodegradable polymers also exhibit a controlled degradation rate to achieve complete resorption within the intended time.

  9. The effect of therapeutic radiation on canine alveolar ridges augmented with hydroxylapatite

    DEFF Research Database (Denmark)

    Pinholt, E M; Kwon, P H

    1992-01-01

    The purpose of this investigation was to evaluate the effect of radiation on hydroxylapatite (HA) implanted subperiosteally for alveolar ridge augmentation in dogs. All bicuspids and molars were extracted from 16 dogs. After 6 weeks, nonporous HA granules were implanted subperiosteally...... on the alveolar ridge. Following 4 months of healing, 12 dogs (experimental group) underwent therapeutic radiation therapy (Co60, 4,000 rad [40 Gy]) to the head and neck region. Four dogs were not irradiated and served as controls. Four animals (three experimental and one control) were killed at 5,6,7, and 8...... months after HA augmentation. Light microscopic evaluation showed that approximately 25% of HA granules were encased by bone while the others were surrounded by fibrous connective tissue. Dissolution of the HA was observed. Microparticles of HA were phagocytized as part of a granulomatous inflammatory...

  10. Complications related to bone augmentation procedures of localized defects in the alveolar ridge. A retrospective clinical study

    DEFF Research Database (Denmark)

    Jensen, Anders Torp; Jensen, Simon Storgård; Worsaae, Nils

    2016-01-01

    PURPOSE: This retrospective clinical study aims to evaluate complications after augmentation of localized bone defects of the alveolar ridge. METHODS: From standardized registrations, the following complications related to bone augmentation procedures were recorded: soft tissue dehiscence, infect...

  11. Alveolar ridge augmentation in rats by combined hydroxylapatite and osteoinductive material

    DEFF Research Database (Denmark)

    Pinholt, E M; Bang, G; Haanaes, H R

    1991-01-01

    , lyophilized dentin or bone and implanted subperiosteally for alveolar ridge augmentation purposes and heterotopically in the abdominal muscles in rats. Light microscopic evaluation revealed that HA was surrounded by fibrous connective tissue containing foreign body giant cells and it had neither......The purpose of this study was to examine if increased bony ingrowth developed when hydroxylapatite was implanted together with an osteoinductive substrate. Dense hydroxylapatite granules (HA) (Calcitite, Calcitek, San Diego, CA, USA) were mixed with equal volumes of allogenic, demineralized...

  12. Resolving of deficit alveolar ridges by induced bone regeneration- case report

    OpenAIRE

    2012-01-01

    The aim was to show illustrative, indication of alveolar augmentation before insertion of endoosseous dental implants. In our case report we have shown the indication for ridge augmentation prior to the placement of endoosseous dental implant. The local process of bone regeneration was thus stimulated and the chances of a good clinical output were increased. Case report: Female patient (27 years old) visited our clinic. Diagnosis was periodontitis of 46 and indication to remove the tooth, ...

  13. Ridge preservation with the use of Bio-Oss collagen: A 6-month study in the dog.

    Science.gov (United States)

    Araújo, Maurício G; Lindhe, Jan

    2009-05-01

    In previous short-term studies, it was observed that while the placement of biomaterial in alveolar sockets may promote bone formation and ridge preservation, the graft may in fact also delay healing. The objective of the present experiment was to evaluate the more long-term effect on hard tissue formation and the amount of ridge augmentation that can occur by the placement of a xenogeneic graft in extraction sockets of dogs. Five beagle dogs were used. The third mandibular premolars were hemi-sected. The distal roots were carefully removed. A graft consisting of Bio-Oss collagen was placed in one socket while the contra-lateral site was left without grafting. After 6 months of healing, the dogs were euthanized and biopsies were sampled. From each experimental site, four ground sections - two from the mesial root and two from the healed socket - were prepared, stained and examined under a microscope. The placement of Bio-Oss collagen in the fresh extraction socket served as a scaffold for tissue modeling but did not enhance new bone formation. In comparison with the non-grafted sites, the dimension of the alveolar process as well as the profile of the ridge was better preserved in Bio-Oss-grafted sites. The placement of a biomaterial in an extraction socket may modify modeling and counteract marginal ridge contraction that occurs following tooth removal.

  14. The functional deformation of maxillary complete dentures in patients with flabby alveolar ridges. Part II: After surgery.

    Science.gov (United States)

    el Ghazali, S; Nilner, K; Wallenius, K

    1991-01-01

    Using strain-gauged maxillary complete dentures, the effects of the surgical removal of soft mobile tissue over the maxillary edentulous alveolar ridges--flabby ridges--on the deformation pattern and magnitude of functional strain were studied in five subjects. The results showed that a 20-90% reduction in denture deformation had taken place after surgery. Furthermore, a pre-operative shear-straining pattern of the buccal flanges and the lateral palatal slopes was not evident post-operatively. The results of this study point on the beneficial value of early surgical removal of flabby maxillary alveolar ridges.

  15. [Alveolar ridge atrophy. The free vascularized fibular flap as alternative treatment in severe alveolar atrophy].

    Science.gov (United States)

    Rohner, Dennis

    2006-01-01

    Implant-supported overdentures are the goal of treatment of the edentulous atrophic jaw. To gain adequate height there is in some instances need for additional bone augmentation. Ridge augmentation using a free vascularised fibular flap is one of the newer techniques. Prefabrication of fibular flaps, as described in this article, is a two-stage procedure to overcome the problems of osseointegration and missing attached gingiva. Accurate pre-operative 3-D-model planning, implant placement and vestibuloplasty in the first stage allow for occlusion driven reconstruction and immediate function in the second stage after a delay of six weeks. Based on our clinical experience the technique and the results are discussed.

  16. The Pontic-Shield: Partial Extraction Therapy for Ridge Preservation and Pontic Site Development.

    Science.gov (United States)

    Gluckman, Howard; Du Toit, Jonathan; Salama, Maurice

    2016-01-01

    Augmentive ridge preservation techniques aim to manage the postextraction ridge. The partial extraction of teeth may better preserve the ridge form by maintaining the bundle bone-periodontal ligament apparatus. Root submergence has been demonstrated to retain the periodontal tissues and preserve the ridge beneath dentures or fixed prostheses. The socket-shield technique entails preparing a tooth root section simultaneous to immediate implant placement and has demonstrated histologic and clinical results contributory to esthetic implant treatment. A retrospective 10-patient case series treating 14 partial extraction sites demonstrates how a modification of the socket-shield technique can successfully develop pontic sites and preserve the ridge.

  17. Titanium implant insertion into dog alveolar ridges augmented by allogenic material

    DEFF Research Database (Denmark)

    Pinholt, E M; Haanaes, H R; Donath, K

    1994-01-01

    The purpose of this investigation was to evaluate whether titanium endosseous implants would osseointegrate in dog alveolar ridges augmented by allogenic material. In 8 dogs en bloc resection, including 2 pre-molars, was performed bilaterally in the maxilla and the mandible. After a healing period...... of 6 weeks allogenic, demineralized and lyophilized dentin or bone was implanted subperiosteally. Titanium implants were installed 5.5 months later in some of the regions. Light and fluorescence microscopic evaluation revealed fibrous encapsulation of the implanted allogenic material, no osteoinduction...... and only minimal osteoconduction, few multinuclear giant cells and a sparse inflammatory reaction. The titanium implants healed mainly by fibrous encapsulation....

  18. Aumento del reborde alveolar residual mediante técnica de rollo Increase of residual alveolar ridge using roll technique

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Simancas Pallares

    2011-03-01

    Full Text Available La pérdida dentaria, asociada a factores sistémicos, patológicos y traumáticos, promueve el proceso de reabsorción ósea de los rebordes residuales y genera problemas funcionales, como la falta de estabilidad y retención de las prótesis dentarias removibles, y disturbios estéticos y psicológicos. Estos defectos varían en dependencia de la cantidad de pérdida ósea y de tejidos blandos que hayan alcanzado. En la actualidad son descritas diversas técnicas que permiten corregir estos defectos. Una de ellas es la técnica del rollo, la cual demuestra muy buenos resultados al aumentar el tamaño del reborde alveolar y disminuir los defectos estéticos que causa sobre todo en el sector anterior. El objetivo del presente artículo es describir el caso clínico de un paciente con pérdida ósea en el sector anterior, tipo III según Seibert, rehabilitado con prótesis parcial fija y sometido a un procedimiento quirúrgico con la técnica del rollo. Se alcanzaron los objetivos planteados y proporciona una mejoría estética así como una mejora en su calidad de vida. Se demostró que con esta técnica se obtienen resultados predecibles que devuelven la estética en zonas de alta exigencia por parte de los pacientes.Tooth loss associated with systemic factors, pathological and traumatic conditions, promotes the bone resorption of residual ridges, this, creates functional problems such as lack of stability and retention of removable dentures as well as aesthetic and psychological disturbances. These defects vary depending on the amount of bone loss and soft tissue they reach. At present there are described various techniques that can correct these defects. One of these is the roll technique which shows very good results by increasing the size of the alveolar ridge and decrease aesthetic defects in the anterior area of the maxilla. The aim of this article is to describe a case of a patient with Seibert bone loss type III, rehabilitated with

  19. Ridge Preservation with Modified “Socket-Shield” Technique: A Methodological Case Series

    Directory of Open Access Journals (Sweden)

    Markus Glocker

    2014-01-01

    Full Text Available After tooth extraction, the alveolar bone undergoes a remodeling process, which leads to horizontal and vertical bone loss. These resorption processes complicate dental rehabilitation, particularly in connection with implants. Various methods of guided bone regeneration (GBR have been described to retain the original dimension of the bone after extraction. Most procedures use filler materials and membranes to support the buccal plate and soft tissue, to stabilize the coagulum and to prevent epithelial ingrowth. It has also been suggested that resorption of the buccal bundle bone can be avoided by leaving a buccal root segment (socket shield technique in place, because the biological integrity of the buccal periodontium (bundle bone remains untouched. This method has also been described in connection with immediate implant placement. The present case report describes three consecutive cases in which a modified method was applied as part of a delayed implantation. The latter was carried out after six months, and during re-entry the new bone formation in the alveolar bone and the residual ridge was clinically evaluated as proof of principle. It was demonstrated that the bone was clinically preserved with this method. Possibilities and limitations are discussed and directions for future research are disclosed.

  20. Histological and morphometric aspects of ridge preservation with a moldable, in situ hardening bone graft substitute

    Directory of Open Access Journals (Sweden)

    Jurišić M.

    2013-01-01

    Full Text Available Biphasic calcium phosphates (BCP are widely used in alveolar ridge regeneration as a porous scaffold for new bone formation. The aim of this case series was to evaluate the regenerative effect of the combination of BCP and polylactide-co-glycolide (PLGA which can serve as a barrier membrane during bone regeneration. The study included five patients. Four months into the healing period, bone samples were collected for histological and morphometric analyses. The results of morphometric analysis showed that newly formed bone represented 32.2 ± 6.8% of the tissue, 31.9 ± 8.9% was occupied by residual graft and 35.9 ± 13.5% by soft tissue. Active osteogenesis was seen around the particles of the graft. The particles were occupied mostly by immature woven bone and connective tissue. The quality and quantity of newly formed bone, after the use of BCP/PLGA for ridge preservation, can be adequate for successful implant therapy after tooth extraction. [Projekat Ministarstva nauke Republike Srbije, br. OI 175021 i br. OI 173009

  1. Minimally traumatic alveolar ridge augmentation with a tunnel injectable thermo-sensitive alginate scaffold

    Directory of Open Access Journals (Sweden)

    Yifen LI

    2015-04-01

    Full Text Available Injectable bone substitutes and techniques have been developed for use in minimally invasive procedures for bone augmentation. Objective : To develop a novel injectable thermo-sensitive alginate hydrogel (TSAH as a scaffold to induce bone regeneration, using a minimally invasive tunnelling technique. Material and Methods : An injectable TSAH was prepared from a copolymer solution of 8.0 wt% Poly(N-isopropylacrylamide (PNIPAAm and 8.0 wt% AAlg-g-PNIPAAm. In vitro properties of the material, such as its microstructure and the sustained release of recombinant human bone morphogenetic protein-2 (rhBMP-2, were investigated. Then, with the subperiosteal tunnelling technique, this material, carrying rhBMP-2, was injected under the labial periosteum of the maxillary anterior alveolar ridge in a rabbit model. New bone formation was evaluated by means of X-ray, micro-computed tomography (micro-CT, fluorescence labelling, histological study, and immunohistochemistry study. Results : The material exhibited good injectability and thermo-irreversible properties. SEM showed an interconnected porous microstructure of the TSAH. The result of ALP activity indicated sustained delivery of BMP-2 from the TSAH from days 3 to 15. In a rabbit model, both TSAH and TSAH/rhBMP-2 induced alveolar ridge augmentation. The percentage of mineralised tissue in the TSAH/rhBMP-2 group (41.6±3.79% was significantly higher than in the TSAH group (31.3±7.21%; p<0.05. The density of the regenerating tissue was higher in the TSAH/rhBMP-2 group than in the other groups (TSAH group, positive control, blank control; p<0.05. Conclusions : The TSAH provided convenient handling properties for clinical application. To some extent, TSAH could induce ridge augmentation and mineral deposition, which can be enhanced when combined with rhBMP-2 for a minimally invasive tunnelling injection.

  2. Lost salt technique for severely resorbed alveolar ridges: An innovative approach

    Directory of Open Access Journals (Sweden)

    Himanshi Aggarwal

    2012-01-01

    Full Text Available The success of a complete denture relies on the principles of retention, stability and support. The prosthodontist skill lies in applying these principles efficiently in critical situations. Severely resorbed maxillary edentulous ridges that are narrow and constricted with increased inter ridge space provide decreased support, retention and stability. The consequent weight of the processed denture only compromises them further. This article describes a case report of an edentulous patient with resorbed ridges where a simplified technique of fabricating a hollow maxillary complete denture using lost salt technique was used for preservation of denture bearing areas. The hollowing of the denture reduces the weight of the denture, thereby enhancing stability and retention, reducing the further resorption of the jaws.

  3. Distracción osteogénica alveolar como método de aumento del reborde alveolar Alveolar osteogenic distraction as method to increase the alveolar ridge

    Directory of Open Access Journals (Sweden)

    Denia Morales Navarro

    2011-03-01

    , disadvantages and complications. A bibliographic review was made by database search of reference systems as MEDLINE and PubliMed using the descriptors "alveolar distraction" o "osteogenic distraction". The published bibliographic sources mainly over 5 years concluding that this technique is an excellent alternative for the bone and soft tissues formation in zones of alveolar atrophy including three stages: latency, distraction and consolidation; being a foreseeable method and with low rates of bone reabsorption compared to other techniques of increase of alveolar ridge. It has its main indication in implant therapy to provide bone volume. We must to individualize each case and to use the more appropriate method according the clinical and personal features of patient. A proper case selection and a better understand of technique are essential to achieve successful results by alveolar osteogenic distraction. In Cuba the alveolar distraction has been not much applied being necessary to expand the studies on this subject matter.

  4. Clinical effects of acrylic resilient denture liners applied to mandibular complete dentures on the alveolar ridge.

    Science.gov (United States)

    Kimoto, S; Kimoto, K; Gunji, A; Kawai, Y; Murakami, H; Tanaka, K; Syu, K; Aoki, H; Toyoda, M; Kobayashi, K

    2007-11-01

    The purpose of this study was to investigate whether resilient denture liners has the potential to decrease problems affecting the alveolar ridge mucosa during the first adjustment session following the initial fitting of the denture. Interventions were complete denture treatment with permanent acrylic resilient denture liner dentures (RLD) in mandibles and conventional heat-activated acrylic resin dentures (ARD) in mandibles. Maxillary dentures were fabricated with conventional heat-activated ARD. Seventy-four subjects were randomly allocated to the RLD and ARD groups by random permuted blocks within the strata method after obtaining written informed consent. A randomized controlled parallel clinical trial with two hospital centres was conducted from April 2004 to July 2006. The problems were comprehensively evaluated by three outcomes with subjective and objective factors as follows: (i) numbers of sore spots, (ii) duration of wearing dentures and (iii) pain perception with 100 mm Visual Analog Scale. The numbers of sore spots in the mandibular support and border areas for the RLD group were significantly less than those for the ARD groups (P dentures an additional day longer than the ARD wearers (P denture liners to mandibular complete dentures provided edentulous patients with fewer problems affecting the alveolar during the first adjustment session following the initial fitting of the denture when compared with conventional denture treatments.

  5. Decoronation of an ankylosed tooth for preservation of alveolar bone prior to implant placement.

    Science.gov (United States)

    Filippi, A; Pohl, Y; von Arx, T

    2001-04-01

    A 12-year-old patient sustained avulsions of both permanent maxillary central incisors. Subsequently, both teeth developed replacement resorption. The left incisor was extracted alio loco. The right incisor was treated by decoronation (removal of crown and pulp, but preservation of the root substance). Comparison of both sites demonstrated complete preservation of the height and width of the alveolar bone at the decoronation site, whereas the tooth extraction site showed considerable bone loss. In addition, some vertical bone apposition was found on top of the decoronated root. Decoronation is a simple and safe surgical procedure for preservation of alveolar bone prior to implant placement. It must be considered as a treatment option for teeth affected by replacement resorption if tooth transplantation is not feasible.

  6. Evaluation of “Autogenous Bioengineered Injectable PRF – Tooth graft” combination (ABIT in reconstruction of maxillary alveolar ridge defects: CBCT volumetric analysis

    Directory of Open Access Journals (Sweden)

    Lydia Nabil Melek

    2017-01-01

    Full Text Available Background: Extracted human teeth were suggested as a source for autogenous bone grafts, especially that they have similar chemical composition to bone. In order to accelerate healing of bone graft over the bony defect, numerous techniques utilizing platelet and fibrinogen concentrations have been introduced in the literature. Objectives: To evaluate clinically and radiographically the use of autogenous tooth bone graft material in combination with injectable platelet-rich fibrin for reconstruction of resorbed maxillary alveolar ridge. Patients and methods: This study was conducted in ten patients indicated for extraction of maxillary anterior or premolar teeth and having maxillary ridge deficiency. Implants were placed after a period of 3 months of bone grafting. The patients were selected from those attending the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University. Results: Clinically, all the patients showed uneventful healing. Radiographically, the results show 30% increase in mean bone density in the period of six months when compared to pre-operative readings. The grafted site showed an increase in the mean volume by 23.47% three months post-operative when compared to the base line measurements preoperatively. Radiographic evaluation of the alveolar ridge after 3 months of grafting showed a significant mean increase in the ridge width and height at the grafted site. Conclusion: Autogenous fresh demineralized tooth graft that is prepared at the chairside after extractions could be considered as the gold standard for socket preservation, bone augmentation in sinuses or filling bone defects, in patients having non restorable teeth indicated for extraction. The adjuvant use of injectable PRF with its high growth factor content may contribute to more favorable and predictable bone formation at the grafted site.

  7. 兔下颌骨前牙区剩余牙槽嵴模型的建立%Establishment of a rabbit model of anterior residual alveolar ridge

    Institute of Scientific and Technical Information of China (English)

    胡杨; 马莹; 何惠宇

    2011-01-01

    背景:建立合适的牙槽嵴缺损动物模型可为开展剩余牙槽嵴的保存、修复研究奠定基础.目的:建立兔下颌骨前牙区剩余牙槽嵴实验动物模型.方法:全麻下完整拔除18只新西兰大白兔双侧下颌中切牙建立兔下颌骨前牙区剩余牙槽嵴模型.术后4,8,12周,处死白兔,游标卡尺测量兔下颌剩余牙槽嵴的长度、宽度和高度,苏木精-伊红染色观察拔牙窝的愈合程度,X射线摄片观察兔下颌拔牙创内骨小梁改建情况.结果与结论:随着手术时间的延长,牙槽嵴长度、宽度和高度均逐渐降低;拔牙窝内有成骨细胞散在分布,新生骨小梁和血管网逐渐形成,牙槽窝持续沉积新生骨组织,与周围牙槽骨界限不清,骨改建生成,拔牙创愈合.苏木精-伊红染色及X射线片均证实兔前牙区剩余牙槽嵴模型建立成功.%BACKGROUND: A proper anterior residual alveolar ridge model can provide basis for the preservation and repair of residual alveolar ridge.OBJECTIVE: to establish a rabbit animal model of anterior residual alveolar ridge.METHODS: The eighteen New Zealand white rabbits were selected, both side of central incisors of 18 rabbits were extracted under the general anesthesia to prepare anterior residual alveolar ridge models. Rabbits were killed at 4, 8, and 12 weeks after operation. The length, width and height of residual alveolar after extraction were measured by Vernier caliper. The healing process of teeth extraction was observed by hematoxylin-eosin staining. The remodeling of bone trabecula in after extraction was examined by X-ray.RESULTS AND CONCLUSION: The length, width and height of residual alveolar ridge were gradually decreased with time prolonged. Osteoblasts could be seen scattered in teeth extraction, new trabecular bone and vascular network was born. The deposition of new bone was continued in teeth extraction, the boundaries between new bone and the alveolar bone was not clear, and new bone

  8. Effect of slow forced eruption on the vertical levels of the interproximal bone and papilla and the width of the alveolar ridge

    Science.gov (United States)

    Kwon, Eun-Young; Lee, Ju-Youn

    2016-01-01

    Objective Forced eruption has been proposed for the reconstruction of deficient bone and soft tissue. The aim of this study was to examine the changes in the alveolar ridge width and the vertical levels of the interproximal bone and papilla following forced eruption. Methods Patients whose hopeless maxillary anterior teeth were expected to undergo severe bone resorption and soft tissue recession upon extraction were recruited. In addition, patients whose maxillary anterior teeth required forced eruption for restoration due to tooth fracture or dental caries were included. Before and after forced eruption, the interproximal bone height was measured by radiographic analysis, and changes in the alveolar ridge width and the interproximal papilla height were measured with an acrylic stent. Results This prospective study demonstrated that the levels of the interproximal alveolar bone and papilla were significantly increased by 1.36 mm and 1.09 mm, respectively, in the vertical direction. However, the alveolar ridge width was significantly reduced by an average of 0.67 mm in the buccolingual direction. The changes in the level of the interproximal alveolar bone and papilla were positively correlated. Conclusions Although the levels of the interproximal bone and papilla were significantly increased, the alveolar ridge width was significantly decreased following forced eruption. There was a modest positive and significant correlation between the changes in the height of the interproximal alveolar bone and the papilla. Based on our findings, modification of vertical forced eruption should be considered when augmentation of the alveolar ridge width is required. PMID:27896212

  9. Systemic non-malignant osteoporosis and reduction of edentulous alveolar ridges

    Directory of Open Access Journals (Sweden)

    Poštić Srđan D

    2014-01-01

    Full Text Available Introduction. Systemic osteoporosis damages skeletal bones to different degrees. The aim of this study was to determine the intensity and correlation of the osteoporotic changes in the bone density of the skeleton and body mass index (BMI with a reduction in edentulous mandibles, and to assess possibility of reparation of layers of mandibles with increase of mineral content in jaws of patients affected by osteoporosis. Material and Methods. In this study, 99 edentulous patients with decreased bone density comprised the experimental group, and 48 edentulous patients with normal bone densities formed the control. The age of the examined patients was 69.02 ± 7,9, range 53-74 of females and 69.11 ± 7.1, range 59-76 years. Radiographs of the hands and panoramic radiographs were done for all the patients. The values of BMI, metacarpal index, density of lumbar spine (L2-L4, in the phalanx and in segments of the mandibles as well as the edentulous alveolar ridges heights were measured, assessed and calculated. Results. The lowest value of the total skeletal density was established in the osteoporotic patients on the basis of the average T-score of- 2.5 in men, and - 2.6 in women. Minimum values of the edentulous ridges heights (right/left, in mm were measured in both osteoporotic females (21.84/22.39 and males 24.90/24.96 patients. By comparison of the densities of the metacarpal bones, proximal phalanx, segments of the edentulous mandibles and based on the numerical values of the edentulous ridges heights, x2 = 3.81 was found in men and x2 = 4.03 was found in women with normal bone densities; x2 = 5.92 was found in men and x2 = 6.25 was found in women with osteopenia; x2 = 2.63 was found in men and x2 = 3.85 was found in women with osteoporosis, on the level of probability of 0.05. After application of calcium and calcitonin in solutions, moderate increment of density (p < 0.05; p < 0.01 was verified, compensating up to 4% of total loss of mass

  10. Alveolar bone preservation subsequent to miniscrew implant placement in a canine model

    DEFF Research Database (Denmark)

    Melsen, Birte; Huja, Sarandeep; Chien, Hua-Hong

    2015-01-01

    on the control side. The bone volume within the cylinders was quantified. An insertion of a dental implant was simulated bilaterally at the insertion site. The height of the clinical crown and the alveolar crest were determined on both sides. The bone turnover was assessed histomorphometrically on un...... across the healing alveolar process results in increased density not only adjacent to the screws, but also in the region where a potential dental implant would be inserted. In humans, the insertion of transcortical screws may maintain bone when for various reasons insertion of a permanent dental implant......-decalcified bucco-lingual sections stained with basic fuchsine and toluidine blue. RESULTS: Comparison of the two sides revealed a significant difference both with regard to the bone volume and morphology. The transcortical screw caused an increase in bone density and less ridge atrophy. When simulating a dental...

  11. Alveolar Ridge Contouring with Free Connective Tissue Graft at Implant Placement: A 5-Year Consecutive Clinical Study.

    Science.gov (United States)

    Hanser, Thomas; Khoury, Fouad

    2016-01-01

    This study evaluated volume stability after alveolar ridge contouring with free connective tissue grafts at implant placement in single-tooth gaps. A total of 52 single-tooth gaps with labial volume deficiencies in the maxilla (incisors, canines, and premolars) were consecutively treated with implants and concomitant free palatal connective tissue grafts in 46 patients between 2006 and 2009. Implants had to be covered with at least 2 mm peri-implant local bone after insertion. At implant placement, a free connective tissue graft from the palate was fixed inside a labial split-thickness flap to form an existing concave buccal alveolar ridge contour due to tissue volume deficiency into a convex shape. Standardized volumetric measurements of the labial alveolar contour using a template were evaluated before connective tissue grafting and at 2 weeks, 1 year, and 5 years after implantprosthetic incorporation. Tissue volume had increased significantly (P tissue contour of the implant before connective tissue grafting to baseline (2 weeks after implant-prosthetic incorporation). Statistically, 50% of the reference points (P > .05) kept their volume from baseline to 1 year after prosthetic incorporation and from baseline to 5 years after prosthetic incorporation, respectively, whereas reference points located within the area of the implant sulcus showed a significant (P connective tissue grafting appears to be an appropriate long-term means to contour preexisting buccal alveolar volume deficiencies in single implants.

  12. Single-stage implantation in the atrophic alveolar ridge of the mandible with the Norian skeletal repair system.

    Science.gov (United States)

    Hölzle, Frank; Bauer, Florian; Kesting, Marco R; Mücke, Thomas; Deppe, Herbert; Wolff, Klaus-Dietrich; Swaid, Sami

    2011-10-01

    Dental implants have played a part in rehabilitation of the jaws for more than 40 years, but in some cases they alone are inadequate because of extreme alveolar resorption. Correction may necessitate a two-stage procedure with additional interventions. We have made a preliminary study of the use of the Norian skeletal repair system (SRS), a carbonated calcium phosphate bone cement used to augment the alveolar ridge as a single-stage procedure, with the placement of implants. Ten edentulous patients with insufficient vertical bone in the interforaminal area were treated. After a horizontal osteotomy and crestal mobilisation of the alveolar ridge, implants were placed through the crestal part and fixed in the basal part of the mandible. Norian SRS was used to fill the gap created. The prostheses were inserted 3 months later. Forty implants were inserted. The follow up period was 60 months, and no fractures or dislocations developed. One of the implants was lost and there was one wound dehiscence, but no surgical intervention or revision was necessary. Radiographs showed good consolidation of the bony structure in all cases. We have described a reliable, single-stage procedure for augmentation and implantation in a highly atrophic alveolar crest. A 98% survival is comparable with those of other techniques. Further clinical trials are necessary to replicate these promising results.

  13. Photoelastic Stress Analysis Surrounding Implant-Supported Prosthesis and Alveolar Ridge on Mandibular Overdentures

    Directory of Open Access Journals (Sweden)

    Dorival Pedroso da Silva

    2010-01-01

    Full Text Available The purpose of this research was to evaluate the maximum stress around osseointegrated implants and alveolar ridge, in a mandible with left partial resection through a photoelastic mandibular model. The first group consisted of two implants: traditional model (T, implants placed in the position of both canines; fulcrum model (F, implants placed in the position of left canine CL and right lateral incisor LiR. Both models linked through a bar and clips. The second group was consisted of three implants, with implants placed in the position of both canines (CR and CL and the right lateral incisor (LiR, which composed four groups: (1 model with 3 “O” rings, (2 model 2 ERAs, bar with clips, (3 model 2 ERAs bar without clips; (4 model “O” ring bar and ERA. An axial and an oblique load of 6.8 kgf was applied on a overdenture at the 1st Pm, 2nd Pm, and 1st M. Results showed that the area around the left canine (CL was practically free of stress; the left lateral incisor (LiL developed only small tensions, and low stress in all the other cases; the right canine tooth suffered the largest concentrations of stress, mainly with the ERA retention mechanism.

  14. Role of Cone Beam Computed Tomography in Rehabilitation of a Traumatised Deficient Maxillary Alveolar Ridge Using Symphyseal Block Graft Placement

    Directory of Open Access Journals (Sweden)

    Shipra Arora

    2013-01-01

    Full Text Available Deficiencies in the alveolar ridges cause multiple problems in achieving aesthetic and functional outcome of implant therapy and are commonly restored by using onlay graft from intraoral source. Careful assessment of the recipient as well as the donor site using cone beam computed tomography (CBCT is a prerequisite to ideal treatment planning. This paper highlights the critical role of CBCT in planning a successful rehabilitation of traumatised deficient anterior maxillary alveolar ridge using autogenous block graft from mandibular symphysis, followed by implant placement. A 21-year-old male reported with missing right maxillary lateral incisor due to traumatic avulsion 6 months back. A concavity was found on the labial aspect of edentulous area. Serial transplanar images on CBCT revealed gross irregular radiolucency in place of labial cortical plate. Using CBCT, size of the required block was estimated, and mandibular symphyseal area was evaluated for the feasibility of harvesting a graft of suitable dimension. Onlay block graft was harvested from mandibular symphysis and placed at the edentulous site to augment the alveolar ridge. Implants were placed 5 months later and loaded successfully after osseointegration. After 1 year of followup, implant-based prosthesis is working well, without any complications.

  15. Alveolar ridge augmentation by connective tissue grafting using a pouch method and modified connective tissue technique: A prospective study

    Directory of Open Access Journals (Sweden)

    Ashish Agarwal

    2015-01-01

    Full Text Available Background: Localized alveolar ridge defect may create physiological and pathological problems. Developments in surgical techniques have made it simpler to change the configuration of a ridge to create a more aesthetic and more easily cleansable shape. The purpose of this study was to compare the efficacy of alveolar ridge augmentation using a subepithelial connective tissue graft in pouch and modified connective tissue graft technique. Materials and Methods: In this randomized, double blind, parallel and prospective study, 40 non-smoker individuals with 40 class III alveolar ridge defects in maxillary anterior were randomly divided in two groups. Group I received modified connective tissue graft, while group II were treated with subepithelial connective tissue graft in pouch technique. The defect size was measured in its horizontal and vertical dimension by utilizing a periodontal probe in a stone cast at base line, after 3 months, and 6 months post surgically. Analysis of variance and Bonferroni post-hoc test were used for statistical analysis. A two-tailed P < 0.05 was considered to be statistically significant. Results: Mean values in horizontal width after 6 months were 4.70 ± 0.87 mm, and 4.05 ± 0.89 mm for group I and II, respectively. Regarding vertical heights, obtained mean values were 4.75 ± 0.97 mm and 3.70 ± 0.92 mm for group I and group II, respectively. Conclusion: Within the limitations of this study, connective tissue graft proposed significantly more improvement as compare to connective tissue graft in pouch.

  16. A rotated palatal flap ridge preservation technique to enhance restorative and hard and soft tissue esthetics for tooth replacement in the anterior maxilla.

    Science.gov (United States)

    Bitter, Robert N

    2010-04-01

    Hard and soft tissue alveolar ridge deformities occur following the extraction of teeth, creating functional and esthetic tooth replacement challenges, especially in the maxillary anterior smile zone. A surgical technique using a rotated palatal flap for ridge preservation is discussed that, whether combined with conventional fixed dentures or implant treatment for tooth replacement, provides the possibility for greatly improved esthetics. This technique, used in combination with or in preparation for implant treatment, allows for preservation of the alveolar bone height and width for improved implant size and placement options. In addition, preservation and enhancement of the soft tissue at the extraction site provides for soft tissue contours adjacent to the definitive restoration that vary little from those of the original natural tooth. Combined with conventional fixed dentures, use of this technique creates a template of the labial and interproximal sulcus of the extracted tooth, allowing for the molding of an ovate pontic replacement tooth. This results in vastly improved restorative emergence profiles with minimal or no change in the height of the labial gingival margin and the form and height of the interproximal papillae with adjacent teeth.

  17. Long-term outcomes of the use of allogeneic, radiation-sterilised bone blocks in reconstruction of the atrophied alveolar ridge in the maxilla and mandible.

    Science.gov (United States)

    Krasny, Marta; Krasny, Kornel; Fiedor, Piotr; Zadurska, Małgorzata; Kamiński, Artur

    2015-12-01

    Increasingly dental surgeons face the challenge of reconstruction of the height and/or thickness of the alveolar ridge as more and more patients wish to have permanent restoration of their dental defects based on intraosseous implants. Evaluation of human allogeneic bone tissue grafts in reconstruction of atrophied alveolar ridge as a pre-implantation procedure. The material comprised 21 patients aged 19-63, treated between 2009 and 2012 by the same surgeon. Restoration of bone tissue defects was performed with allogeneic, frozen, radiation-sterilised, corticocancellous blocks. The study included 26 grafting procedures with 7 procedures consisting in reconstruction of the alveolar ridge in the mandible and 19 in the maxilla. In all the cases the atrophied alveolar ridge was successfully reconstructed, which allowed placement of intraosseous implants in compliance with the initial treatment plan. After the treatment was completed the patients reported for follow-up annually. The average time of follow-up amounted to 39 months (28-50 months). None of the implants was lost during the follow-up period. There was one case of gingival recession causing aesthetics deterioration of the prosthetic restoration. In three cases the connector became unscrewed partially, which was corrected at the same visit. Frozen, radiation-sterilised, allogeneic bone blocks constitute good and durable bone-replacement material allowing effective and long-lasting reconstruction of the atrophied alveolar ridge to support durable, implant-based, prosthetic restoration.

  18. The functional deformation of maxillary complete dentures in patients with flabby alveolar ridges. Part I: Before surgery.

    Science.gov (United States)

    el Ghazali, S; Nilner, K; Wallenius, K

    1991-01-01

    Using strain-guaged duplicate maxillary dentures, the deformation patterns and magnitude of functional strain were studied on five complete denture wearing subjects who had varying amounts of soft mobile tissue over their maxillary edentulous alveolar ridge so called flabby ridges. The thickness of mobile tissue--expressed as depth--was measured by a sharpened periodontal probe with aid of a plastic base plate as a locator. The functional test included maximum biting, and the chewing of three test food samples. The results did not point on any direct relationship between the thickness of the soft tissue and the midline deformation pattern and/or magnitude of functional strain. It seems, however, as if the main influence of mobile tissue is on the strain behaviour in the lateral part of the denture.

  19. Lateral ridge split and immediate implant placement in moderately resorbed alveolar ridges: How much is the added width?

    Science.gov (United States)

    Rahpeyma, Amin; Khajehahmadi, Saeedeh; Hosseini, Vahid Reza

    2013-09-01

    Lateral ridge split technique is a way to solve the problem of the width in narrow ridges with adequate height. Simultaneous insertion of dental implants will considerably reduce the edentulism time. Twenty-five patients who were managed with ridge splitting technique were enrolled. Thirty-eight locations in both jaws with near equal distribution in quadrants received 82 dental fixtures. Beta Tricalcium phosphate (Cerasorb(®) ) was used as biomaterial to fill the intercortical space. Submerged implants were used and 3 months later healing caps were placed. Direct bone measurements before and after split were done with a Collis. Patients were clinically re-evaluated at least 6 months after implant loading. All the data were analyzed by Statistical Package for Social Sciences (SPSS) software version 11.5 (SPSS Inc, Chicago Illinois, USA). Frequency of edentulous spaces and pre/post operative bone width was analyzed. Paired t-test was used for statistical analysis. Difference was considered significant if P value was less than 0.05. Mean value for presplit width was 3.2 ± 0.34 mm while post-split mean width was 5.57 ± 0.49 mm. Mean gain in crest ridge after ridge splitting was 2 ± 0.3 mm. Statistical analysis showed significant differences in width before and after operation ((P > 0.05). All implants (n = 82) survived and were in full function at follow up (at least 6 months after implant loading). Ridge splitting technique in both jaws showed the predictable outcomes, if appropriate cases selected and special attention paid to details; then the waiting time between surgery and beginning of prosthodontic treatment can be reduced to 3 month.

  20. Lateral ridge split and immediate implant placement in moderately resorbed alveolar ridges: How much is the added width?

    Directory of Open Access Journals (Sweden)

    Amin Rahpeyma

    2013-01-01

    Full Text Available Background: Lateral ridge split technique is a way to solve the problem of the width in narrow ridges with adequate height. Simultaneous insertion of dental implants will considerably reduce the edentulism time. Materials and Methods: Twenty-five patients who were managed with ridge splitting technique were enrolled. Thirty-eight locations in both jaws with near equal distribution in quadrants received 82 dental fixtures. Beta Tricalcium phosphate (Cerasorb® was used as biomaterial to fill the intercortical space. Submerged implants were used and 3 months later healing caps were placed. Direct bone measurements before and after split were done with a Collis. Patients were clinically re-evaluated at least 6 months after implant loading. All the data were analyzed by Statistical Package for Social Sciences (SPSS software version 11.5 (SPSS Inc, Chicago Illinois, USA. Frequency of edentulous spaces and pre/post operative bone width was analyzed. Paired t-test was used for statistical analysis. Difference was considered significant if P value was less than 0.05. Results: Mean value for presplit width was 3.2 ± 0.34 mm while post-split mean width was 5.57 ± 0.49 mm. Mean gain in crest ridge after ridge splitting was 2 ± 0.3 mm. Statistical analysis showed significant differences in width before and after operation ((P < 0.05. All implants (n = 82 survived and were in full function at follow up (at least 6 months after implant loading. Conclusion: Ridge splitting technique in both jaws showed the predictable outcomes, if appropriate cases selected and special attention paid to details; then the waiting time between surgery and beginning of prosthodontic treatment can be reduced to 3 month.

  1. Regeneración ósea guiada para el aumento vertical del reborde alveolar Guided osseous regeneration for the vertical augmentation of the alveolar ridge

    Directory of Open Access Journals (Sweden)

    CE Nappe

    2013-04-01

    Full Text Available Se considera como aumento óseo vertical, cualquier técnica que apunte a crear una mayor altura del reborde alveolar. A inicios de la década de los 90’s se empezó a utilizar la regeneración ósea guiada (ROG en mandíbulas atróficas, con el fin de permitir la instalación de implantes óseointegrados. Con el fin de evaluar y exponer parte de la evidencia disponible en la actualidad, con respecto a la ROG para aumento óseo vertical, se realizó la siguiente revisión bibliográfica.Any technique aimed to improve the alveolar ridge height is considered as a vertical bone augmentation procedure. In the early 90’s guided bone regeneration (GBR procedures began to be used in atrophic mandibles to allow the installation of osseointegrated dental implants. The following bibliographic review was made with the purpose of evaluating and exposing part of the available evidence at present in this field.

  2. Clinical and Histomorphometric Assessment of Lateral Alveolar Ridge Augmentation Using a Corticocancellous Freeze-Dried Allograft Bone Block.

    Science.gov (United States)

    Ahmadi, Roya Shariatmadar; Sayar, Ferena; Rakhshan, Vahid; Iranpour, Babak; Jahanbani, Jahanfar; Toumaj, Ahmad; Akhoondi, Nasrin

    2017-06-01

    Horizontal ridge augmentation with allografts has attracted notable attention because of its proper success rate and the lack of disadvantages of autografts. Corticocancellous block allografts have not been adequately studied in humans. Therefore, this study clinically and histomorphometrically evaluated the increase in ridge width after horizontal ridge augmentation using corticocancellous block allografts as well as implant success after 12 to 18 months after implantation. In 10 patients receiving implants (3 women, 7 men; mean age = 45 years), defective maxillary alveolar ridges were horizontally augmented using freeze-dried bone allograft blocks. Ridge widths were measured before augmentation, immediately after augmentation, and ∼6 months later in the reentry surgery for implantation. This was done at points 2 mm (A) and 5 mm (B) apically to the crest. Biopsy cores were acquired from the implantation site. Implant success was assessed 15.1 ± 2.7 months after implantation (range = 12-18 months). Data were analyzed using Friedman and Dunn tests (α = 0.05). At point A, ridge widths were 2.77 ± 0.37, 8.02 ± 0.87, and 6.40 ± 0.66 mm, respectively, before surgery, immediately after surgery, and before implantation. At point B, ridge widths were 3.40 ± 0.39, 9.35 ± 1.16, and 7.40 ± 1.10 mm, respectively, before surgery, immediately after surgery, and before implantation. The Friedman test showed significant increases in ridge widths, both at point A and point B (both P = .0000). Postaugmentation resorption was about 1.5-2 mm and was statistically significant at points A and B (P < .05, Dunn). The percentage of newly formed bone, residual graft material, and soft tissue were 33.0% ± 11.35% (95% confidence interval [CI] = 24.88%-41.12%), 37.50% ± 19.04% (95% CI = 23.88%-51.12%), and 29.5%, respectively. The inflammation was limited to grades 1 or zero. Twelve to 18 months after implantation, no implants caused pain or showed exudates or pockets. Radiographic

  3. 牙槽骨扩展增加骨量后的植牙术%The implantation of teeth after doing alveolar ridge augmentation

    Institute of Scientific and Technical Information of China (English)

    王银龙; 孙少宣; 周健; 何家才; 王元银; 唐燕

    2001-01-01

    Objective To observe the clinical effects of alveolar ridge augm entation by using dense polycrystal particulate hydroxyapatite(HA) in dental implant.Methods 26 alveolar ridges with alveolar bone loss has increased alveolar bone quantity by doing alveolar ridge augmentation before dental implants are implanted. By the same way, 6 alveolar ridges used submucous-perio steal tunnel.Results  All the 26 dental implants were successful after doing alveolar ridge augmentation for 3.2 months. The implanted HA did not move or diffuse, and it was strongly combined with base bone.Of the 6 alveolar ridges using submucous-periosteal tunnel method of HA implantation, 5 dental I mplants were successful, and 1 was failed after 4.8 months. By this way, the implanted HA moved and diffused on some degree. It was mainly surrounded the base bone by fibrous tissue and a small part of new bone grew into base bone. Conclusion By doing alveolar ridge augmentation,the indication of dental implant can be greatly extended, its course of treatment is shortened and its success rate is increased .%目的观察运用致密羟基磷灰石(HA)微粒,在颌骨萎缩患者牙槽嵴上行牙槽骨扩展术后行人工种植牙的临床效果。方法使用HA颗粒采用牙槽骨扩展术和粘骨膜下隧道法,对26例颌骨萎缩患者增加牙槽骨骨量后行人工种植牙。结果牙槽骨扩展术后置入HA颗粒不移位不弥散,与基骨牢固相接,人工种植牙时间为术后3.2个月,26例全部成功;粘骨膜下隧道术6 例置入HA颗粒都有不同程度移位、弥散,与基骨大多为纤维性包裹及部分新骨长入,人工种植牙时间为术后4.8个月,1例失败。结论运用牙槽骨扩展术大大地扩大了人工种植牙的适应证、缩短疗程和提高成功率。

  4. Biphasic alloplastic graft used to preserve the dimension of the edentulous ridge: an experimental study in the dog.

    Science.gov (United States)

    Lindhe, J; Araújo, M G; Bufler, M; Liljenberg, B

    2013-10-01

    Loss of teeth results in marked qualitative and quantitative alterations of the alveolar process at the edentulous site. It was observed that a graft comprised of bovine bone mineral placed in the fresh extraction socket delayed tissue modeling, but preserved the dimension of the ridge at edentulous sites. To analyze the influence of a biphasic synthetic graft on tissue modeling and remodeling during healing of extraction wounds. Five beagle dogs were used. Two premolars in the maxilla and two in the mandible were included. Full thickness flaps were elevated and the distal roots were removed. An alloplastic graft (BPCAP; α-TCP core coated with nanocrystalline biomimetic hydroxyapatite) embedded in porcine collagen was placed to fill the fresh extraction socket of the premolar sites. Flaps were replaced to cover the entrance of the extraction sockets during early healing. The extraction and grafting procedures were scheduled to allow for the study of 1, 2, and 3 months socket healing. The biopsies from the maxillary sites were decalcified, embedded in paraffin, and stained to allow the study of various aspects of hard tissue formation. The biopsies from the mandibular sites were processed for ground sectioning and used to evaluate alterations of ridge dimensions after 3 months of socket healing. It was documented that the biphasic alloplastic graft did not undergo marked resorption during tissue modeling and remodeling, but allowed large amounts of bone to form within the post-extraction site. Grafting the experimental sites with this biomaterial furthermore counteracted ridge resorption that otherwise occurs following tooth extraction. © 2012 John Wiley & Sons A/S.

  5. MICROECOLOGY OF THE MUCOUS MEMBRANE OF THE ALVEOLAR RIDGES IN THE PERIOD OF ADAPTATION TO COMPLETE DENTURES

    Directory of Open Access Journals (Sweden)

    Yanishen I. V.,

    2016-06-01

    quantitative composition of the biocenosis. It is established that the microflora of the alveolar ridge in patients with edentulous consisted of associations of yeasts from 2-5 representatives of the microbial world. It is established that in patients of the experimental group on the 7th day of withdrawal 3-component microbial associations has decreased in 1.3 times, whereas the 4-component associations were recorded in 1.4 times more often compared with the initial period of observation. For patients with adhesive frequency of detection of 2-component microbial associations 30-the day of the research was 1.3 times higher than prior to the setting of the prosthesis. Identify 5 component associations for 30-the day, has decreased in 2 times. In patients without adhesive (control group 4-component microbial associations in the mouth after a week of adaptation to the prosthesis were detected in 1.6 times, and 30 days – in 2 times more often than to prosthetics. The weight 5 component associations through the week remained at the initial level, while after 30 days has increased in 1,5 times. The structure microbiocenosis the mucous of the oral cavity patients with edentulism are represented 13 genera of bacteria and morilioid fungi of the genus Candida, allocated in secondary amounts by lg (2,5±0,19 to lg (5,4±0,17 CFU/g. When adhesive between denture base and mucosa of the alveolar ridge frequency of withdrawal and the density of microbial colonization in the adaptation period were not statistically different. But the density of the microbial population among the control group increased 1.5 times for Enterococcus spp, 1.4 for the Klebsiella spp and 1.6 times for yeast fungi Candida spp. Found a significant decrease in microbial density of the representatives of the resident microflora in 1.4 times for Neisseria spp, 1.6-fold for Lactobacillus spp (p<0.05. Conclusion. The results of these studies indicate significant changes of qualitative and quantitative structure of

  6. Hard and Soft Tissue Management of a Localized Alveolar Ridge Atrophy with Autogenous Sources and Biomaterials: A Challenging Clinical Case

    Science.gov (United States)

    Andreoni, D.

    2016-01-01

    Particularly in the premaxillary area, the stability of hard and soft tissues plays a pivotal role in the success of the rehabilitation from both a functional and aesthetic aspect. The present case report describes the clinical management of a localized alveolar ridge atrophy in the area of the upper right canine associated with a thin gingival biotype with a lack of keratinized tissue. An autogenous bone block harvested from the chin associated with heterologous bone particles was used to replace the missing bone, allowing for a prosthetic driven implant placement. Soft tissues deficiency was corrected by means of a combined epithelialized and subepithelial connective tissue graft. The 3-year clinical and radiological follow-up demonstrated symmetric gingival levels of the upper canines, with physiological peri-implant probing depths and bone loss. Thus, the use of autogenous tissues combined with biomaterials might be considered a reliable technique in case of highly aesthetic demanding cases.

  7. Multiple Congenital Epulis in Alveolar Ridges of Maxilla and Mandible in a Newborn: A Rare Case Report

    Directory of Open Access Journals (Sweden)

    Nader Saki

    2014-01-01

    Full Text Available Congenital granular cell lesion (CGCL or congenital epulis is an uncommon benign of the oral cavity tumor appearing at birth with typical clinical and pathologic features. It predominately affects females, mainly on the anterior maxillary alveolar ridge, and occurs usually as a single mass, although sometimes as multiple. The left side incisor area is the most common site. The etiology and histogenesis of the lesion remain obscure. Though it is a benign lesion, the tumor may cause feeding and respiratory problems if there are too large or multiple tumors. We report a case of a three-day-old, female newborn, who was referred to our hospital with multiple congenital oral swellings arising from the maxilla and mandible. The tumors caused a feeding problem and, hence, they were resected by surgical excision under general anesthesia.

  8. Hard and Soft Tissue Management of a Localized Alveolar Ridge Atrophy with Autogenous Sources and Biomaterials: A Challenging Clinical Case

    Directory of Open Access Journals (Sweden)

    C. Maiorana

    2016-01-01

    Full Text Available Particularly in the premaxillary area, the stability of hard and soft tissues plays a pivotal role in the success of the rehabilitation from both a functional and aesthetic aspect. The present case report describes the clinical management of a localized alveolar ridge atrophy in the area of the upper right canine associated with a thin gingival biotype with a lack of keratinized tissue. An autogenous bone block harvested from the chin associated with heterologous bone particles was used to replace the missing bone, allowing for a prosthetic driven implant placement. Soft tissues deficiency was corrected by means of a combined epithelialized and subepithelial connective tissue graft. The 3-year clinical and radiological follow-up demonstrated symmetric gingival levels of the upper canines, with physiological peri-implant probing depths and bone loss. Thus, the use of autogenous tissues combined with biomaterials might be considered a reliable technique in case of highly aesthetic demanding cases.

  9. The influence of Aloe vera and xenograft XCB toward of bone morpho protein 2 BMP2 expression and amount of osteoblast of alveolar bone induced into tooth extraction sockets Cavia cobaya

    OpenAIRE

    Utari Kresnoadi; Retno Pudji Rahayu

    2014-01-01

    Tooth extraction can cause inflammation leading to alveolar ridge resorption. In addition, prominent ridge has crucial role for making denture su-ccessfully. Thus, socket preservation is needed to prevent greater alveolar ridge resorption. An innovative material, a combination of Aloe vera and xe-nograft (XCB), is then considered as a biogenic stimulator that can reduce inflammation, as a result, the growth of alveolar bone is expected to be impro-ved. This research is aimed to prove whether ...

  10. Distracción osteogénica alveolar: una alternativa en la reconstrucción de rebordes alveolares atróficos: Descripción de 10 casos Alveolar distraction osteogenesis: an alternative in the reconstruction of atrophic alveolar ridges: Report of 10 cases

    Directory of Open Access Journals (Sweden)

    P.E. Maurette O’Brien

    2004-02-01

    Full Text Available La distracción osteogénica alveolar (DOA es un método alternativo para la reconstrucción de rebordes alveolares atróficos que ofrece un resultado previsible y que disminuye los tiempo de espera entre la reconstrucción del reborde alveolar atrófico y la colocación de los implantes óseo-integrados, en comparación con los métodos tradicionalmente utilizados. Fueron atendidos 10 pacientes que presentaban deficiencia de reborde alveolar mandibular y/o maxilar por medio de distracción osteogénica, utilizando un dispositivo yuxtaoseo (Conexión Implant System® - SP-Brasil. Todos los pacientes fueron atendidos de forma ambulatoria, bajo anestesia local y sedación conciente, comenzando la activación del dispositivo a los 7 días posteriores a la instalación, con un patrón de activación de 1 mm diarios hasta alcanzar la altura ósea deseada. Posteriormente se aguardaron 10 semanas como parte del periodo de consolidación ósea y se realizo la colocación de los implantes oseointegrados y local y el retiro del dispositivo de distracción, pudiéndose comprobar clínica y radiográficamente la ganancia de la altura y volumen óseo necesario para la rehabilitación por medio de implantes.The alveolar distraction osteogenesis is an alternative method for the reconstruction of atrophic alveolar ridges with success, that decrease the time of wait between the reconstruction of the alveolar ridge and the placement of the osseointegrated implants in comparison with the traditionally used methods. 10 patients that presented deficiency of the alveolar ridge in the maxilla and/or mandible were assisted by means of distraction osteogenesis, using a juxtaosseous device (Conexion Implant System® - SP-Brazil. All the patients were assisted of form ambulatory, under local anesthesia and conscientious sedation, beginning the activation from the device 7 days later to the installation, with a pattern of activation 1 mm diary until reaching the wanted

  11. Mapping the Metal Uptake in Plants from Jasper Ridge Biological Preserve - Oral Presentation

    Energy Technology Data Exchange (ETDEWEB)

    Lo, Allison [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2015-08-24

    Serpentine soil originates in the Earth’s mantle and contains high concentrations of potentially toxic transition metals. Although serpentine soil limits plant growth, endemic and adapted plants at Jasper Ridge Biological Preserve, located behind SLAC National Accelerator Laboratory, can tolerate these conditions. Serpentine soil and seeds belonging to native California and invasive plants were collected at Jasper Ridge. The seeds were grown hydroponically and on serpentine and potting soil to examine the uptake and distribution of ions in the roots and shoots using synchrotron micro-focused X-ray fluorescence spectroscopy. The results were used to determine differences between serpentinetolerant plants. Rye grown on potting soil was enriched in Ni, Fe, Mn, and Cr compared to purple needlegrass grown on serpentine soil. Serpentine vegetation equally suppressed the uptake of Mn, Ni, and Fe in the roots and shoots. The uptake of Ca and Mg affected the uptake of other elements such as K, S, and P.

  12. Assessment of Temperature Rise and Time of Alveolar Ridge Splitting by Means of Er:YAG Laser, Piezosurgery, and Surgical Saw: An Ex Vivo Study

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    Jacek Matys

    2016-01-01

    Full Text Available The most common adverse effect after bone cutting is a thermal damage. The aim of our study was to evaluate the bone temperature rise during an alveolar ridge splitting, rating the time needed to perform this procedure and the time to raise the temperature of a bone by 10°C, as well as to evaluate the bone carbonization occurrence. The research included 60 mandibles (n=60 of adult pigs, divided into 4 groups (n=15. Two vertical and one horizontal cut have been done in an alveolar ridge using Er:YAG laser with set power of 200 mJ (G1, 400 mJ (G2, piezosurgery unit (G3, and a saw (G4. The temperature was measured by K-type thermocouple. The highest temperature gradient was noted for piezosurgery on the buccal and lingual side of mandible. The temperature rises on the bone surface along with the increase of laser power. The lower time needed to perform ridge splitting was measured for a saw, piezosurgery, and Er:YAG laser with power of 400 mJ and 200 mJ, respectively. The temperature rise measured on the bone over 10°C and bone carbonization occurrence was not reported in all study groups. Piezosurgery, Er:YAG laser (200 mJ and 400 mJ, and surgical saw are useful and safe tools in ridge splitting surgery.

  13. Assessment of Temperature Rise and Time of Alveolar Ridge Splitting by Means of Er:YAG Laser, Piezosurgery, and Surgical Saw: An Ex Vivo Study.

    Science.gov (United States)

    Matys, Jacek; Flieger, Rafał; Dominiak, Marzena

    2016-01-01

    The most common adverse effect after bone cutting is a thermal damage. The aim of our study was to evaluate the bone temperature rise during an alveolar ridge splitting, rating the time needed to perform this procedure and the time to raise the temperature of a bone by 10°C, as well as to evaluate the bone carbonization occurrence. The research included 60 mandibles (n = 60) of adult pigs, divided into 4 groups (n = 15). Two vertical and one horizontal cut have been done in an alveolar ridge using Er:YAG laser with set power of 200 mJ (G1), 400 mJ (G2), piezosurgery unit (G3), and a saw (G4). The temperature was measured by K-type thermocouple. The highest temperature gradient was noted for piezosurgery on the buccal and lingual side of mandible. The temperature rises on the bone surface along with the increase of laser power. The lower time needed to perform ridge splitting was measured for a saw, piezosurgery, and Er:YAG laser with power of 400 mJ and 200 mJ, respectively. The temperature rise measured on the bone over 10°C and bone carbonization occurrence was not reported in all study groups. Piezosurgery, Er:YAG laser (200 mJ and 400 mJ), and surgical saw are useful and safe tools in ridge splitting surgery.

  14. Ridge preservation in cases requiring tooth extraction during endodontic surgery: a case report.

    Science.gov (United States)

    Lin, S; Cohenca, N; Muska, E A; Front, E

    2008-05-01

    To provide a treatment option to endodontists performing surgery that will enhance ridge preservation when tooth extraction is required. A 47-year-old woman was referred to an endodontic practice for apical root-end resection of tooth 22 because of refractory periradicular disease. Radiographic examination revealed a large periradicular lesion, 5 mm in diameter and a root-end filling at the root apex. The treatment plan included exploratory surgery and apical root-end resection. A vertical root fracture was diagnosed and the decision was made to extract the tooth. The socket was grafted with a cancellous bovine bone and covered with a resorbable collagen membrane. Follow-up examination revealed favourable bone healing with formation of a new cortical plate and the preservation of soft tissue width and height in the aesthetic area. The principles of guided bone regeneration. Preserving or reconstructing the extraction socket. Enhances the ability to restore function and provide aesthetically pleasing restorations to patients without violating the predictability and function of the prostheses.

  15. Dimensional Changes in Alveolar Ridge Following Extraction of Teeth in the Maxillary Premolar Area in Subjects with Thick and Thin Gingival Biotypes: A Pilot Study.

    Science.gov (United States)

    Abdelhafez, Reem S; Alhabashneh, Rola; Khader, Yousef; Hijazi, Mohammed; Jarah, Mohammed

    2016-01-01

    This study investigated changes in residual ridge dimensions after tooth extraction among thin and thick gingival biotypes. Fifteen patients who required extraction of maxillary premolars were classified according to gingival biotypes (10 teeth in 9 participants were included in the thick group, and 6 teeth in 6 participants were included in the thin group). Minimally traumatic extractions were carried out using periotomes and rotational movement of teeth. At the time of extraction an osteometer was used to measure the thickness of the labial plate and the bony alveolar ridge at the extraction site by penetrating the tissues until bone was reached 5 mm, 7 mm, and 10 mm below the midpoint of the crest of the facial and palatal gingival margins. Standardized radiographs were taken immediately and after 3 months. The results of this study show minimal differences in dimensional changes following extraction of premolar teeth in thick and thin gingival biotypes. Significantly greater bone loss was detected in both gingival biotypes when the labial plate thickness was less than 1.5 mm, especially in alveolar ridge height.

  16. A contemporary approach for treatment planning of horizontally resorbed alveolar ridge: Ridge split technique with simultaneous implant placement using platelet rich fibrin membrane application in mandibular anterior region.

    Science.gov (United States)

    Parthiban, Prathahini S; Lakshmi, R Vijaya; Mahendra, Jaideep; Sreekumar, K; Namasivayam, Ambalavanan

    2017-01-01

    Treatment of edentulous sites with horizontal atrophy represents a clinical situation in which the positioning of endosseous implants might be complex or sometimes impossible without a staged regenerative approach. This case report presents management of horizontally deficient mandibular anterior ridge with a contemporary approach to treatment planning and application of platelet-rich fibrin membrane for ridge split technique and simultaneous implant placement. Implants in anterior mandibular area are considered to be most predictable, stable, with high success rate and patients' satisfaction with implant esthetics. In contrast to traditional ridge augmentation techniques, ridge splitting allows for immediate implant placement following surgery and eradicates the possible morbidity from a second surgical site.

  17. [Usefulness of pulsed water jet in dissecting sphenoid ridge meningioma while preserving arteries].

    Science.gov (United States)

    Endo, Toshiki; Nakagawa, Atsuhiro; Fujimura, Miki; Sonoda, Yukihiko; Shimizu, Hiroaki; Tominaga, Teiji

    2014-11-01

    We report the utility of a pulsed water jet device in meningioma surgery. The presented case is that of a 61-year-old woman with left visual disturbance. MRI demonstrated heterogeneously enhanced mass with intratumoral hemorrhage, indicating sphenoid ridge meningioma on her left side. The tumor invaded the cavernous sinus and left optic canal, engulfing the internal carotid artery in the carotid cistern and encased middle cerebral arteries. During the operation, the pulsed water jet device was useful for dissecting the tumor away from the arteries since it was safe in light of preserving parent arteries. The jet did not cause any vascular injury and did not induce vasospasm as shown by postoperative symptomatology and MRIs. With the aid of pulsed water jet, we could achieve total resection of the tumor except for the piece within the cavernous sinus. The patient had no new neurological deficits after the operation. We consider the pulsed water jet as a useful device, especially when the need to dissect meningioma from parent arteries exists. The jet can help neurosurgeons simultaneously achieve tumor resection and preservation of blood vessels.

  18. Clinical effects on the prevention of alveolar bone absorption by site preservation after tooth extraction due to periodontitis%牙周炎患牙位点保存术的临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    孙俊毅; 汪明敏; 董凯; 朱春晖; 刘瑾; 董妍; 李昂

    2016-01-01

    preservation improved the alveolar bone defects (P<0.05).After site preservation for 6 months,CBCT analysis showed that the density of new alveolar bone markedly enhanced compared with regular extraction group.Conclusion The technique of site preservation after tooth extraction due to periodontitis is a method which can prevent and reduce disuse atrophy absorption of the alveolar ridge so that the height and width of the alveolar bone can meet aesthetic requirements.

  19. Ridge preservation comparing socket allograft alone to socket allograft plus facial overlay xenograft: a clinical and histologic study in humans.

    Science.gov (United States)

    Poulias, Evmenios; Greenwell, Henry; Hill, Margaret; Morton, Dean; Vidal, Ricardo; Shumway, Brian; Peterson, Thomas L

    2013-11-01

    Previous studies of ridge preservation showed a loss of ≈18% or 1.5 mm of crestal ridge width in spite of treatment. The primary aim of this randomized, controlled, masked clinical trial is to compare a socket graft to the same treatment plus a buccal overlay graft, both with a polylactide membrane, to determine if loss of ridge width can be prevented by use of an overlay graft. Twelve patients who served as positive controls received an intrasocket mineralized cancellous allograft (socket group), and 12 patients received the same socket graft procedure plus buccal overlay cancellous xenograft (overlay group). Horizontal ridge dimensions were measured with a digital caliper, and vertical ridge changes were measured from a stent. Before implant placement, at 4 months, a trephine core was obtained for histologic analysis. The mean horizontal ridge width at the crest for the socket group decreased from 8.7 ± 1.0 to 7.1 ± 1.5 mm for a mean loss of 1.6 ± 0.8 mm (P overlay group decreased from 8.4 ± 1.4 to 8.1 ± 1.4 mm for a mean loss of 0.3 ± 0.9 mm (P >0.05). The overlay group was significantly different from the socket group (P overlay group had 40% ± 16% (P >0.05). The overlay treatment significantly prevented loss of ridge width and preserved or augmented the buccal contour. The socket and overlay groups healed with a high percentage of vital bone.

  20. Augmentation of the atrophic maxillary alveolar ridge with hydroxyapatite granules in a Vicryl (polyglactin 910) knitted tube and simultaneous open vestibuloplasty.

    Science.gov (United States)

    Sugar, A W; Thielens, P; Stafford, G D; Willins, M J

    1995-04-01

    A modified technique for augmentation of the severely atrophic edentulous maxillary alveolar ridge is described. The augmentation was carried out using a knitted polyglactin 910 mesh tube filled with porous hydroxyapatite granules, the tube being inserted through the access achieved by an open vestibuloplasty. The results of an in-vivo animal study showed that the absorption of the mesh was complete between 49 and 70 days. The clinical study included 11 patients in all of whom there was severe maxillary ridge atrophy and major prosthetic problems; follow-up was for a mean of 25 months. The procedure was without significant complication and produced a mean immediate absolute augmentation of 5.5 mm and substantially increased vestibular depth. A gradual reduction of ridge height was found over time. Nevertheless all patients showed significantly increased ability to wear their dentures. The technique is presented as a safe and predictable alternative to the use of bone grafts and titanium implants in these severely atrophic cases.

  1. 低平牙槽嵴全口义齿的印模技术%A impressing technique for edentulous patients with severely resorbed edentulous alveolar ridge

    Institute of Scientific and Technical Information of China (English)

    宓勇

    2013-01-01

    Secondary impression and window tray technique were used to make accurate final impression for edentulous patients with low and flat alveolar ridge.This method can improve the retention,fitness and chewing efficiency of complete dentures.%用二次印模法加开窗减压印模技术取得全口义齿精确的终印模.对于低平牙槽嵴患者,该印模法能提高印模准确性,有助于提高低平牙槽嵴全口义齿的固位力和咀嚼效率,减少复诊次数.

  2. Bone augmentation procedures in localized defects in the alveolar ridge: clinical results with different bone grafts and bone-substitute materials

    DEFF Research Database (Denmark)

    Jensen, Simon Storgård; Terheyden, Hendrik

    2009-01-01

    periods. The heterogeneity of the available data did not allow identifying one superior grafting protocol for any of the osseous defect types under investigation. However, a series of grafting materials can be considered well-documented for different indications based on this review. There is a high level......PURPOSE: The objective of this review was to evaluate the efficacy of different grafting protocols for the augmentation of localized alveolar ridge defects. MATERIALS AND METHODS: A MEDLINE search and an additional hand search of selected journals were performed to identify all levels of clinical...... evidence except expert opinions. Any publication written in English and including 10 or more patients with at least 12 months of follow-up after loading of the implants was eligible for this review. The results were categorized according to the presenting defect type: (1) dehiscence and fenestration...

  3. Alveolar distraction osteogenesis vs. vertical guided bone regeneration for the correction of vertically deficient edentulous ridges: a 1-3-year prospective study on humans.

    Science.gov (United States)

    Chiapasco, Matteo; Romeo, Eugenio; Casentini, Paolo; Rimondini, Lia

    2004-02-01

    The purpose of this prospective study was to compare vertical guided bone regeneration (GBR) and vertical distraction osteogenesis (DO) for their ability in correcting vertically deficient alveolar ridges and their ability in maintaining over time the vertical bone gain obtained before and after implant placement. Eleven patients (group 1) were treated by means of vertical GBR with autogenous bone and e-PTFE membranes, while 10 patients (group 2) were treated by means of DO. In group 1, six patients received implants at the time of GBR (subgroup 1A), while five patients had implants placed at the time of membrane removal (subgroup 1B). In group 2, implants were placed at the time of distraction device removal. A total of 25 implants were placed in group 1 and 34 implants were placed in group 2 patients. Three to 5 months after implant placement, patients were rehabilitated with implant-borne dental prostheses. The following parameters were evaluated: (a) bone resorption of the regenerated ridges before and after implant placement; (b) peri-implant clinical parameters 1, 2, and 3 years after prosthetic loading of implants; (c) survival and success rates of implants. Bone resorption values before and after implant placement were significantly higher in group 1. The results suggested that both techniques may improve the deficit of vertically resorbed edentulous ridges, although distraction osteogenesis seems to be more predictable as far as the long-term prognosis of vertical bone gain is concerned. Implant survival rates as well as peri-implant clinical parameters do not differ significantly between the two groups, whereas the success rate of implants placed in group 2 patients was higher than that obtained in group 1 patients.

  4. 上颌即刻种植后牙槽骨改建的CBCT分析%CBCT Assessment of Alveolar Ridge Variations Following Immediate Implant in the Maxilla

    Institute of Scientific and Technical Information of China (English)

    刘向辉; 张磊; 黄辉; 张静东; 张林; 沈彬

    2015-01-01

    Objective: To analyze the factors which may influence the maxillary alveolar ridge alterations after immediate implantation. Methods:Data were obtained from 80 patients who received immediate dental implants (80 implants) in an-terior and premolar segments in maxilla. Following data were recorded: ① The distance between the implant surface and the outer border of the bone crest.②The distance between the implant surface and the inner border of the bone crest. ③The vertical residual gap were checked. The above variables were examined again four months later. Statistical treatment was based on the following principles: ① The thickness of the buccal bone wall. ② The position of the missing tooth. ③The cause of tooth extraction. Results: In cases which the buccal bone wall was thick, the amount of bone absorption was small. In the premolar segment, the absorption of alveolar ridge was less than the incisor-canine segment. Conclusion:The thickness of buccal bone wall and position of missing tooth, may influence the maxillary alveolar ridge alterations after im-mediate implantation. Clinicians must consider the thinkness of the buccal bony wall and the horizontal gap in the practice during immediate implants.%目的:分析即刻种植术后可能影响上颌牙槽嵴改建的因素。方法:共80例接受上颌即刻种植的患者,在上颌前牙及前磨牙区拔牙后即刻植入80枚种植体。检查并记录如下数据:①种植体表面距颊侧牙槽嵴外侧骨板的距离;②种植体颊侧水平骨缺损距离;③种植体颊侧垂直缺损距离。并于术后4个月行二期手术时复查上述数据。依据以下3个原则进行分析:颊侧牙槽骨厚度;缺牙位置;是否因牙周病拔牙。结果:当颊侧骨板较厚时,牙槽嵴吸收量较少。前磨牙区域牙槽嵴吸收量较少。结论:颊侧骨板的厚度及缺牙位置均有可能影响术后牙槽嵴的改建。在行即刻种植术时,临床医

  5. Pressure produced on the residual maxillary alveolar ridge by different impression materials and tray design: an in vivo study.

    Science.gov (United States)

    Reddy, Subash M; Mohan, Chenthil Arun; Vijitha, D; Balasubramanian, R; Satish, A; Kumar, Mahendira

    2013-12-01

    Increased ridge resorption may occur due to inappropriate pressure applied during final impression making phase of complete denture fabrication. This study was done to evaluate the pressure applied on the residual ridge while making impressions with two tray designs (with and without spacer) using, zinc oxide eugenol and light body polyvinyl siloxane impression material. Five edentulous subjects were randomly selected. For each of the five subjects four maxillary final impressions were made and were labelled as, Group A-Impression made with tray without spacer using zinc oxide eugenol impression, Group B-Impression made with tray with spacer using zinc oxide eugenol impression material, Group C-Impression made with tray without spacer using light body polyvinyl siloxane impression material, Group D-Impression made with tray with spacer using light body polyvinyl siloxane impression material. During the impression procedure a closed hydraulic system was used to remotely measure the pressures produced in three areas. The pressure produced were calibrated according to the micro strain record. Statistical comparisons of readings were done using t test and ANOVA. The acquired data revealed that ZOE produced an average pressures value of 26.534 and 72.05 microstrain, while light body PVS produced 11.430 and 37.584 microstrain value with and without spacer respectively. Significantly high values were recorded on the vault of the palate when using trays without spacer. The use of light body polyvinyl siloxane and zinc oxide eugenol impression material showed insignificant difference. Within the limitations of this study, tray design has a significantly effected on the pressures produced, while the impression materials does not have any significant difference.

  6. Assessment of Temperature Rise and Time of Alveolar Ridge Splitting by Means of Er:YAG Laser, Piezosurgery, and Surgical Saw: An Ex Vivo Study

    National Research Council Canada - National Science Library

    Matys, Jacek; Flieger, Rafał; Dominiak, Marzena

    2016-01-01

    ... to the significant loss of alveolar bone additionally surgical procedures are necessary [2]. Augmentation of the resorbed alveolar crest can be achieved, for example, with onlay bone grafts, membrane tech...

  7. Scale politics, vernacular memory and the preservation of the Green Ridge battlefield in Kampar, Malaysia.

    NARCIS (Netherlands)

    Muzaini, H.B.

    2013-01-01

    In the now burgeoning scholarship on memory, there is a discernible shift from considering the politics of dominant public memory towards sites of counter-memories where vernacular forms of memory activism take place. This paper contributes to this by focusing its attention on plans to preserve

  8. Scale politics, vernacular memory and the preservation of the Green Ridge battlefield in Kampar, Malaysia.

    NARCIS (Netherlands)

    Muzaini, H.B.

    2013-01-01

    In the now burgeoning scholarship on memory, there is a discernible shift from considering the politics of dominant public memory towards sites of counter-memories where vernacular forms of memory activism take place. This paper contributes to this by focusing its attention on plans to preserve Gree

  9. Hard tissue augmentation for alveolar defects before implant placement

    Directory of Open Access Journals (Sweden)

    Mutia Rochmawati

    2017-08-01

    Full Text Available Background. Often when planning implant therapy, there is a need to augment or  replace  bone  that  has  been  lost. The alveolar defects may occur as a result of tooth loss due to extraction, advanced periodontal diseases or trauma, long term use of removable appliances, dehiscence and fenestration defects, developmental defects/clefts, congenitally missing teeth and odontogenic cysts and tumors. Insufficient bone volume can be brought about by hard tissue augmentation. This techniques have led to increased predictability in reconstruction of alveolar ridge defects and functional implant placement. Purpose. To describe the methods of hard tissue augmentation which can be done with block grafts (autografts and allografts, particulate grafts (cortical and cancellous, xenografts, or synthetic materials. Review. The reconstruction of a normal alveolar housing, in height and width, is imperative to achieve a harmonious balance between biology, function, and aesthetics. Depending on the size and morphology of the defect, horizontal or vertical, various augmentation procedures can be used. Soft tissue management is a critical aspect of hard tissue augmentation procedures. Incisions, reflection, and manipulation should be designed to optimize blood supply and wound closure. The design and management of mucoperiosteal flaps must consider the increased dimensions of the ridge after augmentation as well as esthetics and approximation of the wound margins. The surgical procedure needs to be executed with utmost care to preserve the maximum vascularity to the flap and minimize tissue injury. Conclusion. Alveolar ridge defects can be classified by using Seibert’s classification or HVC System. The treatment of alveolar ridge defect before implant placement can be done with hard tissue augmentation.

  10. The Effect of Gingival and Alveolar Ridge Trimmed Surgical in Dental Restoration%牙龈与牙槽嵴修整手术在牙齿修复中的效果

    Institute of Scientific and Technical Information of China (English)

    梁凤林

    2015-01-01

    目的 分析牙龈与牙槽嵴修整手术在牙齿修复中的效果.方法 选取我院收治的60例行牙齿修复的患者作为观察对象,收治时间为2011年3月~2014年8月,随机分成两组,每组30例.对照组采取牙冠修复术,实验组在牙冠修复术前采取牙龈与牙槽嵴修整手术,比较两组患者治疗后的临床疗效及患者的满意度.结果 两组患者的满意度及总有效率的比较,差异有统计学意义(P<0.05).结论 对行牙齿修复的患者在牙冠修复术前采取牙龈与牙槽嵴修整手术,能够有效提高患者的满意度.%Objective To analyze results of the gingival and alveolar ridge trimmed surgical in dental restoration.Methods 60 patients admitted to our hospital treated by routine dental restoration as the observed object from March 2011 to August 2014. They were randomly divided into two groups,30 cases each. The control group took the crown prosthetics,and the experimental group taking the crown prosthetics gingival and alveolar ridge dressing operation. Two groups' efficacy and patient satisfaction were compared after treatment.Results Satisfaction and overal efficiency of the two groups had difference,and the difference was statisticaly significant(P<0.05).Conclusion sFor patients with dental restorations before taking the crown prosthetics took gingival and alveolar ridge repair surgery,can effectively improve patients' satisfaction.

  11. Mapping the metal uptake in plants from Jasper Ridge Biological Preserve using synchrotron micro-focused X-ray fluorescence spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Lo, Allison [Univ. of California, Davis, CA (United States)

    2015-08-20

    Serpentine soil originates in the Earth’s mantle and contains high concentrations of potentially toxic transition metals. Although serpentine soil limits plant growth, endemic and adapted plants at Jasper Ridge Biological Preserve, located behind SLAC National Accelerator Laboratory, can tolerate these conditions. Serpentine soil and seeds belonging to native California and invasive plants were collected at Jasper Ridge. The seeds were grown hydroponically and on serpentine and potting soil to examine the uptake and distribution of ions in the roots and shoots using synchrotron micro-focused X-ray fluorescence spectroscopy. The results were used to determine differences between serpentine-tolerant plants. Rye grown on potting soil was enriched in Ni, Fe, Mn, and Cr compared to purple needlegrass grown on serpentine soil. Serpentine vegetation equally suppressed the uptake of Mn, Ni, and Fe in the roots and shoots. The uptake of Ca and Mg affected the uptake of other elements such as K, S, and P.

  12. Analysis of socket preservation using polylactide and polyglycolide (PLA-PGA) sponge: a clinical, radiographic, and histologic study.

    Science.gov (United States)

    Madan, Rohit; Mohan, Ranjana; Bains, Vivek K; Gupta, Vivek; Singh, G P; Madan, Mani

    2014-01-01

    The aim of this study was to evaluate the extraction socket healing and dimensional changes following alveolar ridge preservation using polylactide and polyglycolide (PLA-PGA) sponge. Fifteen patients were selected for alveolar socket preservation immediately following tooth extraction. Monoradicular maxillary and mandibular teeth were evaluated. The selected sockets had intact sockets walls with a minimum of 7 mm of residual alveolar bone height. The test sites were thoroughly debrided and grafted with PLA-PGA sponge, while the control sites underwent natural healing. Computed tomography (CT) measurements were taken at baseline and 6 months. After 6 months of healing, final CT measurements were performed, and trephine core biopsy specimens were obtained for histologic analysis. Implants were placed immediately after biopsy harvesting. All subjects completed the study, and all sites healed without adverse events and allowed for implant placement. The mean difference in socket height, width, and density after 6 months was statistically significantly higher in the test sites compared with control sites. Clinical measurement at the midbuccal site of the alveolar socket showed a mean loss of 2.45 ± 0.67 mm in the control group, compared with a mean gain of 1.28 ± 0.58 mm in the test group. All test sites showed minimal ridge alterations, and statistically significant differences were observed between the test and control sites with respect to bone composition and horizontal and vertical bone loss, indicating that PLA-PGA sponge is suitable for alveolar ridge preservation.

  13. Histomorhological and clinical evaluation of maxillary alveolar ridge reconstruction after craniofacial trauma by applying combination of allogeneic and autogenous bone graft.

    Science.gov (United States)

    De Ponte, Francesco Saverio; Falzea, Roberto; Runci, Michele; Siniscalchi, Enrico Nastro; Lauritano, Floriana; Bramanti, Ennio; Cervino, Gabriele; Cicciu, Marco

    2017-02-01

    A variety of techniques and materials for the rehabilitation and reconstruction of traumatized maxillary ridges prior to dental implants placement have been described in literature. Autogenous bone grafting is considered ideal by many researchers and it still remains the most predictable and documented method. The aim of this report is to underline the effectiveness of using allogeneic bone graft for managing maxillofacial trauma. A case of a 30-year-old male with severely atrophic maxillary ridge as a consequence of complex craniofacial injury is presented here. Augmentation procedure in two stages was performed using allogeneic and autogenous bone grafts in different areas of the osseous defect. Four months after grafting, during the implants placement surgery, samples of both sectors were withdrawn and submitted to histological evaluation. On the examination of the specimens, treated by hematoxylin and eosin staining, the morphology of integrated allogeneic bone grafts was revealed to be similar to the autologous bone. Our clinical experience shows how the allogeneic bone graft presented normal bone tissue architecture and is highly vascularized, and it can be used for reconstruction of severe trauma of the maxilla.

  14. Histomorhological and clinical evaluation of maxillary alveolar ridge reconstruction after craniofacial trauma by applying combination of allogeneic and autogenous bone graft

    Directory of Open Access Journals (Sweden)

    Francesco Saverio De Ponte

    2017-02-01

    Full Text Available A variety of techniques and materials for the rehabilitation and reconstruction of traumatized maxillary ridges prior to dental implants placement have been described in literature. Autogenous bone grafting is considered ideal by many researchers and it still remains the most predictable and documented method. The aim of this report is to underline the effectiveness of using allogeneic bone graft for managing maxillofacial trauma. A case of a 30-year-old male with severely atrophic maxillary ridge as a consequence of complex craniofacial injury is presented here. Augmentation procedure in two stages was performed using allogeneic and autogenous bone grafts in different areas of the osseous defect. Four months after grafting, during the implants placement surgery, samples of both sectors were withdrawn and submitted to histological evaluation. On the examination of the specimens, treated by hematoxylin and eosin staining, the morphology of integrated allogeneic bone grafts was revealed to be similar to the autologous bone. Our clinical experience shows how the allogeneic bone graft presented normal bone tissue architecture and is highly vascularized, and it can be used for reconstruction of severe trauma of the maxilla.

  15. Clinical and genetic study on 356 Brazilian patients with a distinct phenotype of cleft lip and palate without alveolar ridge involvement.

    Science.gov (United States)

    Alvarez, Camila Wenceslau; Guion-Almeida, Maria Leine; Richieri-Costa, Antonio

    2014-12-01

    Oral clefts include cleft lip (CL), cleft lip with cleft palate (CLP) and cleft palate (CP), with wide variations in clinical presentation and degree of severity. We described a sample of individuals with CL and CP without alveolar arch involvement (CL + CP) to verify if the characteristics of this group are distinct from those with CL with or without CP (CL/P) described in literature. The sample was composed of 356 patients with CL + CP, registered at HRCA-USP, Bauru-SP-Brazil. The following characteristics were investigated: sex ratio, parental age at the time of conception, parental consanguinity, familial recurrence, laterality of the cleft and associated anomalies. A subgroup of 30 individuals with microforms of CL and CP were taken from the sample and compared with the remaining cases. Statistical differences were found between this CL + CP sample and the literature data for groups with CL/P regarding laterality, sex ratio, consanguinity, familial recurrence, and the presence of associated anomalies. The microform sample showed a statistical difference in paternal age. In most evaluated aspects, this sample presents similar characteristics to the consulted literature data for CL/P; as do the group of microform cleft cases when compared with the remaining CL + CP sample in this study. Microforms of cleft can represent a target group for investigation into the embryogenetic mechanisms of oral clefts and their phenotypic variability. Copyright © 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  16. 原核表达的重组人骨形态发生蛋白7增高牙槽嵴的实验%Experimental study on recombinant human bone morphogenetic protein-7 expressed in prokaryocyte augmenting alveolar ridge

    Institute of Scientific and Technical Information of China (English)

    肖水清; 卞翠荣

    2006-01-01

    BACKGROUND: After loss of teeth, the dynamic equilibrium between osteoblast and osteoclast in alveolar bone is destroyed because of systematic and local factors, and residual ridge resorption and atrophy occur irreversibly, which result in the loss of massive alveolar bone. Bone morphogenetic protein-7 (BMP-7) exerts an important effect in the development and traumatic repair of bone and tooth.OBJECTIVE: To investigate the effect of human recombinant bone morphogenetic protein-7 (rhBMP-7) on new bone formation of alveolar ridge and absorption of alveolar ridge.DESIGN: Control experiment.SETTING: Department of Orthodontics, Jinan Stomatological Hospital;Shangdong Academy of Medical Sciences.MATERIALS: This study was conducted at the Shangdong Academy of Medical Sciences from June 2003 to December 2004. Totally 28 New Zealand white rabbits, of either gender, weighing 2 kg, were used in this study.METHODS: Animal extracted wound models were created on the rabbits.The mandibular left and right central incisor of the rabbits were removed.Two carriers containing BMP7 complex (40 μg/each) were implanted into the mandibular right central incisor (experimental group), two empty carriers containing only phosphate buffer solution(PBS) (40 μg/each) were implanted into the mandibular left central incisor (control group). The animals were sacrificed at postoperative 2, 4, 8 and 12 weeks. The specimen from the operated regions were harvested and observed by scanning electron microscope, and calcium content and alkaline phosphatase (ALP) activity were also measured.MAIN OUTCOME MEASURES: ① Result of scanning electron microscope (SEM). ② ALP activity and calcium content.RESULTS: ① The bone wound healing was 4-6 weeks earlier in the experimental group than in the control group . ② The ALP activity was significantly higher in the experimental group than in the control group [week 2:(38.191±5.384, (19.821±2.084) μkat/g;week 4: (160.815±9.669), (126.709±1.634)

  17. Evaluación clínica y radiográfica de la técnica de distracción osteogénica en la reconstrucción de rebordes alveolares atróficos en la región anterior del maxilar superior A clinical and radiographic evaluation of the distraction osteogenesis technique for the reconstruction of atrophic alveolar ridges in the anterior region of the upper maxilla

    Directory of Open Access Journals (Sweden)

    M.E. Allais de Maurette

    2005-06-01

    Full Text Available Este estudio tiene como objetivo evaluar clínica y radiográficamente la técnica de distracción osteogénica alveolar en la región anterior del maxilar superior y las posibles complicaciones que pueden aparecer durante el tratamiento. Fueron evaluados 15 pacientes, sometidos a reconstrucción alveolar del maxilar superior en la región anterior con distracción osteogénica, usando un distractor yuxtaóseo. Del total de 15 pacientes encontramos que 13 pacientes (86,6% obtuvieron un éxito total de la técnica, obteniendo una ganancia ósea real media de 7,04 mm; en 1 paciente (6,66% fue parcial (2,62 mm y en 1 paciente (6,66% se evidenció un fracaso en la técnica, al alcanzar solo 0,76 mm debido a problemas en la activación del distractor. En cuanto a las complicaciones surgidas durante el tratamiento fueron divididas en complicaciones menores, toda aquella que no interfirió en el éxito del tratamiento, y que estuvieron presentes en 8 pacientes (53,33%, y complicaciones mayores aquellas que no permitieron la rehabilitación con implantes, y que fue encontrado solo en 1 paciente (6,66%. La técnica de distracción osteogénica alveolar, demostró ser eficaz en la reconstrucción de rebordes alveolares atróficos con un éxito de 93,33%, presentado pequeñas complicaciones que pueden ser solventadas por medio de un seguimiento por parte del profesional.This study evaluates clinically and radiographically the distraction osteogenesis technique for the reconstruction of atrophic alveolar ridges in the anterior maxilla region, and the possible complications that arise during treatment. Fifteen patients were evaluated, clinically and radiographically, that had been treated with alveolar distraction osteogenesis in the anterior region, using a juxta-osseous distractor. In 13 patients (86.6% the technique was completely successful, there being an effective bone gain of 7,04 mm. In 1 patient (6.66% this was partial (2.62 mm and in 1 patient (6

  18. [Alveolar hemorrhage].

    Science.gov (United States)

    Parrot, A; Fartoukh, M; Cadranel, J

    2015-04-01

    Alveolar hemorrhage occurs relatively rarely and is a therapeutic emergency because it can quickly lead to acute respiratory failure, which can be fatal. Hemoptysis associated with anemia and pulmonary infiltrates suggest the diagnosis of alveolar hemorrhage, but may be absent in one third of cases including patients in respiratory distress. The diagnosis of alveolar hemorrhage is based on the findings of a bronchoalveolar lavage. The causes are numerous. It is important to identify alveolar hemorrhage due to sepsis, then separate an autoimmune cause (vasculitis associated with antineutrophil cytoplasmic antibody, connective tissue disease and Goodpasture's syndrome) with the search for autoantibodies and biopsies from readily accessible organs, from a non-immune cause, performing echocardiography. Lung biopsy should be necessary only in exceptional cases. If the hemorrhage has an immune cause, treatment with steroids and cyclophosphamide may be started. The indications for treatment with rituximab are beginning to be established (forms that are not severe and refractory forms). The benefit of plasma exchange is unquestionable in Goodpasture's syndrome. In patients with an immune disease that can lead to an alveolar hemorrhage, removing any source of infection is the first priority. Copyright © 2014 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  19. Ridge preservation with acellular dermal matrix and anorganic bone matrix cell-binding peptide P-15 after tooth extraction in humans. A histologic and morphometric study

    Directory of Open Access Journals (Sweden)

    Arthur B. Novaes Jr

    2012-06-01

    Full Text Available Aim: The aim of this study was to analyze by histomorphometric parameters the use of acellular dermal matrix (ADM with or without anorganic bovine bone matrix (ABM / synthetic cell-binding peptide P-15 in the formation of bone in human alveoli. Materials and methods: Eighteen patients in need of extraction of maxillary anterior teeth were selected and randomly assigned to the test group (ADM plus ABM/P-15 or the control group (ADM only. Histomorphometric measurements and histological analysis were recorded about 6 months after ridge preservation procedures in ten patients. The amount of newly formed bone, the most recently formed bone, fibrous tissue plus marrow spaces and remaining graft particles were measured and analyzed. Results: At 6 months, the new bone area parameter and the percentage of fibrous tissue plus marrow space areas showed higher values to the control group, and statistically significant differences when compared with the test group (p=0.03. Conclusion: The ADM acted as a membrane. The association of ABM/P-15 with ADM resulted in new bone formation within the alveoli, but the results were not considered relevant when used in this indication.

  20. 双尖牙区即刻种植位点保存的CBCT观察研究%Effects of Immediate Implant Placement on Socket and Ridge Preservation in the Bicuspid Region:a CBCT Evaluation

    Institute of Scientific and Technical Information of China (English)

    尹伟; 刘向辉; 孙卫革; 王晨辰

    2016-01-01

    目的:利用锥形束CT(cone-beam computed tomography,CBCT)综合评估临床中双尖牙区采用即刻种植和引导骨组织再生技术(guided bone regeneration,GBR)进行位点保存的效果。方法:选择双尖牙需拔除并行种植修复的患者65例90颗牙,随机分为即刻种植GBR组(即刻种植+引导骨组织再生)、单纯GBR组(拔牙创GBR技术处理+延期种植)和空白对照组(拔牙创常规处理+延期种植)。拔牙前及拔牙后1、3、6个月分别行CBCT扫描,测量牙槽骨高度和宽度,并用Simplant软件测量位点骨密度,比较各时间点3组间各指标差异,评价位点保存的效果。结果:各时间点骨高度丧失量、骨宽度丧失量及骨密度变化值相比,即刻种植GBR组变化最小,单纯GBR处理组次之,空白对照组最大,每2组间差异均有统计学意义(P<0.05)。结论:双尖牙区应用即刻种植联合GBR处理,可有效进行种植位点保存,并能减少患者就诊次数,简化种植修复程序,适合在临床推广应用。%Objective:The purpose of the present study was to evaluate the clinical site preservation effected by using im-mediate implanting technology in the bicuspid region. Methods:65 patients (90 teeth) received informed consents with re-moval of bicuspid teeth were randomly divided into 3 groups: immediate implanting + GBR (guided bone regeneration) group (30 teeth), GBR alone group (30 teeth), and the control group (30 teeth). CBCT scanning examination was per-formed before and 1-, 3-, and 6-month after tooth extraction, to evaluate the alveolar bone height, width, and bone miner-al density with the help of Simplant software. Results: The changes of bone height,width, and bone density at each time-point of "immediate implanting+GBR" group showed the smallest , and there was a significant difference among the 3 groups (P<0.05). Conclusion:"Immediate implanting+GBR"can effectively achieve the socket

  1. Application of nano crystal collagen base bone and hydroxy soda lime in treatment alveolar ridge bone deficiency%纳米晶胶原基骨和羟基碱石灰在牙槽嵴骨量不足治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    王焱

    2013-01-01

    目的 探讨纳米晶胶原基骨和羟基碱石灰在牙槽嵴骨量不足患者牙种植术治疗中的临床疗效.方法 选择应用纳米晶胶原基骨和羟基磷灰石治疗牙槽嵴骨量不足的牙种植术患者为研究对象,根据入院先后随机分为纳米晶胶原基骨组和羟基碱石灰组,对比分析两种方法治疗牙槽嵴骨量不足的临床疗效.结果 纳米晶胶原基骨组临床痊愈率明显高于羟基磷灰石组(p<0.05).羟基磷灰石组与纳米晶胶原基骨组骨增量后牙槽嵴平均宽度均较术前明显增加(P<0.01).两组治疗后差异无统计学意义(P>0.05).结论 纳米晶胶原基骨治疗牙种植术牙槽嵴骨量不足疗效满意,值得临床进一步研究推广.%Objective To explore the clinical effect of dental implants surgery alveolar ridge bone deficiency treating with nano crystal collagen base bone and hydroxy soda lime.Methods To choose dental implants surgery patients who had dental implants surgery alveolar ridge bone deficiency treating with nano crystal collagen base bone and hydroxy soda lime as the research object,according to the admission they were randomly divided into nanometer crystal collagen base bone group and hydroxy soda lime group,and the clinical effect of the two metheds was comparatively analyzed.Results The cure rate of the bone-grafting group was obviously higher than the hydroxyapatite group(P <0.05).The average width alveolar ridge after bone incremental of hydroxyapatite group and bone-grafting group compared with preoperation were all increased significantly(P <0.01),but the two groups after treating comparison had no significant differences (P > 0.05).Conclusion The clinical effect of dental implants art alveolar ridge bone mass insufficient treating with bone-grafting is satisfied,and the further research is worth clinical promotion.

  2. 3D-Printed Scaffolds and Biomaterials: Review of Alveolar Bone Augmentation and Periodontal Regeneration Applications

    Directory of Open Access Journals (Sweden)

    Farah Asa’ad

    2016-01-01

    Full Text Available To ensure a successful dental implant therapy, the presence of adequate vertical and horizontal alveolar bone is fundamental. However, an insufficient amount of alveolar ridge in both dimensions is often encountered in dental practice due to the consequences of oral diseases and tooth loss. Although postextraction socket preservation has been adopted to lessen the need for such invasive approaches, it utilizes bone grafting materials, which have limitations that could negatively affect the quality of bone formation. To overcome the drawbacks of routinely employed grafting materials, bone graft substitutes such as 3D scaffolds have been recently investigated in the dental field. In this review, we highlight different biomaterials suitable for 3D scaffold fabrication, with a focus on “3D-printed” ones as bone graft substitutes that might be convenient for various applications related to implant therapy. We also briefly discuss their possible adoption for periodontal regeneration.

  3. 3D-Printed Scaffolds and Biomaterials: Review of Alveolar Bone Augmentation and Periodontal Regeneration Applications

    Science.gov (United States)

    Asa'ad, Farah; Giannì, Aldo Bruno; Giannobile, William V.; Rasperini, Giulio

    2016-01-01

    To ensure a successful dental implant therapy, the presence of adequate vertical and horizontal alveolar bone is fundamental. However, an insufficient amount of alveolar ridge in both dimensions is often encountered in dental practice due to the consequences of oral diseases and tooth loss. Although postextraction socket preservation has been adopted to lessen the need for such invasive approaches, it utilizes bone grafting materials, which have limitations that could negatively affect the quality of bone formation. To overcome the drawbacks of routinely employed grafting materials, bone graft substitutes such as 3D scaffolds have been recently investigated in the dental field. In this review, we highlight different biomaterials suitable for 3D scaffold fabrication, with a focus on “3D-printed” ones as bone graft substitutes that might be convenient for various applications related to implant therapy. We also briefly discuss their possible adoption for periodontal regeneration. PMID:27366149

  4. Complications in the treatment with alveolar extraosseous distractors. Literature review

    OpenAIRE

    Rodriguez Grandjean, Alfredo; Reininger, David; López Quiles, Juan

    2015-01-01

    Background To review the literature that analyses the types and frequency of complications associated with the use of extraosseous alveolar distraction from 2007 to 2013. Material and Methods Review of the literature in PubMed, using these keywords; alveolar ridge, alveolar distraction osteogenesis, complication, literature review. Inclusion criteria were: articles published between 2007 and 2013 that included the distraction protocol, the complications encountered and the time when they occu...

  5. Dental implants placed on bone subjected to vertical alveolar distraction show the same performance as those placed on primitive bone

    OpenAIRE

    Pérez Sayáns, Mario; León Camacho, María De Los Ángeles; Somoza Martín, José Manuel; Fernández González, Beatriz; Blanes-Vázquez-Gundín, Silvia; Gándara Rey, José Manuel; García García, Abel

    2013-01-01

    Introduction: Vertical osteogenic alveolar distraction (VOAD) allows for the augmentation of the alveolar ridge for the placement of dental implants in atrophic alveolar ridges. The goal of this paper is to assess long-term peri-implant bone resorption in implants placed on bones subjected to VOAD, comparing it with a group of patients who had implants placed directly on the alveolar bone without previous bone regeneration. Material and Methods: We conducted a follow-up study on 32 patients w...

  6. Alveolar ridge augmentation by osteoinduction in rats

    DEFF Research Database (Denmark)

    Pinholt, E M; Bang, G; Haanaes, H R

    1990-01-01

    performed subperiosteally on the premaxilla and heterotopically in the abdominal muscles of rats. Light microscopic evaluations revealed that all allogenic, demineralized, and lyophilized dentin and bone implants induced new bone formation. No inflammatory or foreign body reactions were observed....

  7. The Importance of Immediate Bone Block Autograft to Successfully Restore the Function and Aesthetic of the Anterior Alveolar Process and Teeth.

    Science.gov (United States)

    Singer, Lawrence David

    2015-12-01

    Maxillofacial traumatic injuries can damage the jaw, teeth, and soft tissues of the head and neck region. When these injuries occur, best practice is to reconstruct as comprehensively as is clinically prudent at time of injury. Smart and efficient procedures during the initial surgery can minimize subsequent reconstructive procedures in scope and number, minimize expense, and result in a better final aesthetic and functional outcome. Restoration of anterior alveolar jaw fractures with comminuted or avulsed segments becomes a complex prospect when left untreated after initial trauma or injury and can result in alveolar ridge defects that are difficult, costly, and cumbersome to repair. This case report details one 19-year-old woman who had a traumatic injury in these areas and has a best result outcome because of immediate reconstruction efforts involving a bone block autograft to preserve alveolar process anatomy.

  8. Evaluation of alveolar ridge reconstruction and esthetic result following immediate implant%即刻种植术后牙槽突骨板改建及美学效果评价

    Institute of Scientific and Technical Information of China (English)

    王莺; 林野; 陈波; 张宇; 邸萍

    2016-01-01

    LCS)为3的有18个牙位,LCS为4的有2个;永久修复后1年LCS为2的有14个,LCS为3的有5个。术前牙间乳头指数(papilla index score,PSI)为2的有5个牙位,PSI为3的有15个牙位;永久修复后1年PSI为2的有7个牙位,PSI为3的有13个牙位,经过Willcoxon秩和检验,术前与永久修复后1年LCS比较差异均有统计学意义(P<0.001),PSI术前与永久修复后1年比较变化差异无统计学意义(P=0.157)。结论:即刻种植术后不能避免牙槽嵴改建而导致的牙槽骨改建吸收;即刻种植后切牙牙间乳头高度可以得到较好的维持,唇侧软组织丰满度由于牙槽骨改建而难以维持;即刻种植修复存在美学风险。%Objective:To evaluate the bone alteration subject to remodeling and analyze the esthetic result following immediate implant placement of incisors.Methods:In this study,20 patients (1 3 women,7 men)were involved,who needed implants for incisors of maxilla.The patients received 23 im-mediate implants totally.On the day of surgery and 6 months after the implants were placed,Cone beam CT (CBCT)was taken.The thickness of the alveolar ridge and the vertical change of marginal bone levels onthe mesial and distal aspects of theimplants were measured using the computer software (Planme-caRomexis Viewer 3.6.0.R).The evaluation of esthetic result by labial convexity score (LCS)and pa-pilla index score (PIS)were analyzed pre-operation and one year after the final crown was delivered.The statistics with paired-t test for the measurement data and Willcoxon test for rating data were done by SPSS 20.0.Results:The survival rate in the two-year follow-up was 1 00%.The measuring point 1 (MP1 ), MP2,MP3 and MP4 (0,2,4,6 mm apical to the implant platform,respectively)got significant altera-tions after 6 months of the follow-up.These differences were statistically significant (P<0.05 ).The major alteration happened at MP1 and MP4,which got (-0.89 ±2.06)mm and

  9. Alveolar dimensional changes relevant to implant placement after minimally traumatic tooth extraction with primary closure.

    Science.gov (United States)

    Carranza, Nelson; Bonta, Hernan; Gualtieri, Ariel F; Rojas, Mariana A; Galli, Federico G; Caride, Facundo

    2016-09-01

    The purpose of this study is to evaluate the dimensional changes that occur in the alveolar ridge after minimally traumatic tooth extraction by means of computed tomography (CT), with special focus on the portion of bone supporting the gingival zenith. Twenty subjects with indication for singlerooted tooth extraction and preserved alveolar walls were selected for this study. After a minimally traumatic extraction, two CT scans were performed; the first within 24 hours postextraction (TC1) and the second 6 months (TC2) later. A radiographic guide with a radiopaque marker was used to obtain references that enabled accurate measurements over time, in both vertical and horizontal directions. The bone crest immediately apical to the gingival zenith was identified and termed "osseous zenith". The displacement of the osseous zenith in horizontal and vertical direction was analyzed and correlated with several alveolar anatomical variables with the aim of identifying possible predictors for bone remodeling. Dimensional changes that occur in postextraction sockets within a 6month period showed significant vertical and horizontal displacement of the osseous zenith (p 3 mm) should be expected. The present study suggests that the width of the alveolar crest at its midlevel, rather than crestal width, may be correlated with the displacement of the osseous zenith. Sociedad Argentina de Investigación Odontológica.

  10. Influence of balanced occlusion in complete dentures on the decrease in reduction of an edentulous ridge

    Directory of Open Access Journals (Sweden)

    Poštić Srđan D.

    2012-01-01

    Full Text Available Background/Aim. Balanced occlusal arrangement of artificial teeth and balanced occlusion is a specific type of occlusion that preserves the stability of complete dentures. Balanced occlusion comprises realization of tooth contacts at the working side as well as at the balancing side, at the same time. The aim of this study was to assess the influence of balanced occlusal arrangement of artificial teeth on the decrease in reduction of edentulous alveolar ridge. Methods. A longitudinal study on 91 fully edentulous patients was conducted using their panoramic radiographs and parameters of vertical dimension of edentulous ridges. All the patients were clinically examined by the same and a qualified dental practitioner. Numerical values of parameters of vertical dimensions of edentulous ridges and lines were statistically processed and compared using the Student’s t-test. Results. Vertical dimensions and heights of edentulous ridges were different after comparison of parameters in complete denture wearers with balanced occlusion and complete denture wearers without bilaterally balanced occlusion, as well as between male and female edentulous patients. Statistically significant differences of heights were established in complete denture wearers’ with a set of artificial teeth without balanced occlusion, at the baseline and 12 months after wearing of complete dentures. Conclusion. Balanced occlusion is a favored occlusal design in setting of artificial teeth in conventional complete dentures, which preserves edentulous ridge and influence the stability of dentures.

  11. An interdisciplinary management of severely resorbed maxillary anterior ridge complicated by traumatic bite using a ridge splitting technique

    Science.gov (United States)

    Gupta, Narender Dev; Maheshwari, Sandhya; Chaudhari, Prabhat Kumar; Rathi, Shraddha

    2015-01-01

    Injury to the teeth and alveolar ridge of the maxillary anterior region due to trauma can cause severe alveolar ridge deficiency. Ridge augmentation is a valuable periodontal plastic surgical method for the correction of ridge defects for esthetic purpose. Although ridge augmentation can help to restore the ridge volume, the grafting procedures can significantly increase the patient morbidity, treatment time, and the cost. Among the ridge augmentation techniques, the ridge split procedure demonstrates many benefits such as no need for donor site, the rare risk of damage to underlying anatomical structures, less pain, and swelling. This case report presents a vertical split technique for increasing the bone volume. There was a remarkable healing and significant increase in bone volume. We have followed the case for 6 months. PMID:25810602

  12. Comparison of autogenous mucosal grafts and collagen-based, solvent-preserved allografts for vestibuloplasty.

    Science.gov (United States)

    Sezer, Bahar; Selçuk, Ender; Ertürk, Selda; Gomel, Murat

    2004-03-01

    This study was designed to determine whether solvent-preserved dura mater and fascia lata grafts would be as effective as palatal mucosal grafts for vestibuloplasty. All graft systems succeeded in covering the alveolar ridge with firmly attached tissue, which is needed to ensure prosthetic stability. There was no remarkable reduction in area until the stents were removed. However, after 6 months of vestibuloplasty, there was a significant reduction in gained vestibular area in the fascia lata group, whereas no significant difference between dura mater and palatal grafts was observed. These findings suggest that dura mater could serve as a biologic oral dressing for mucosal defects as effectively as palatal grafts in vestibuloplasty.

  13. 三种排齐方式对下切牙牙龈及牙槽嵴高度的影响比较%Comparison of influences of different orthodontic alignment methods on gingival margin and alveolar ridge height of mandibular incisors

    Institute of Scientific and Technical Information of China (English)

    米晓晖; 吴勇

    2015-01-01

    目的:比较常规直丝弓矫治、低摩擦力矫治及自动漂移三种排齐方式对下前牙牙龈及牙槽嵴高度的影响。方法选取下前牙拥挤患者53例,常规组22例,低摩擦力组15例,结合自动漂移组12例。在治疗前(T0)及排齐完成(T1)记录临床牙冠长度,拍摄锥束CT测量下切牙唇舌侧及近远中牙槽嵴高度,头颅定位侧位片测量下前牙唇倾度及垂直向位置。配对 t 检验比较治疗前后数据,Duncan法分析三组样本间各指标均数变化差异。结果结合自动漂移组临床牙冠增长(0.11±0.62)mm,较其他两组变化少(P<0.01)。唇侧牙槽嵴高度三组病例在排齐后均降低(P<0.01),其中常规组降低最多,为(0.70±0.42)mm;结合自动漂移组最少,为(0.29±0.63)mm。舌侧牙槽嵴高度变化三组间无显著性差异(P>0.05)。近中及远中牙槽嵴高度常规组排齐后降低(P<0.001),其他两组治疗前后无显著性差异。切牙唇倾度排齐后均增加,常规组增加(2.19±1.35)°,低摩擦力组增加(1.07±0.89)°,结合自动漂移组增加了(0.24±0.72)°,三组间差异有显著性(P<0.001)。结论三种不同排齐方式在排齐阶段对下切牙牙龈及牙槽骨高度的影响程度不同。常规组影响最大,低摩擦力组次之,结合自动漂移组最小。建议对于牙龈退缩及牙槽嵴吸收风险较高的拥挤患者采用轻缓的排齐方式。%ObjectiveThis prospective study was performed to compare the influences of three orthodontic alignment methods on the level of the gingival margin and alveolar ridge height of mandibular incisors.Methods53 individuals with mandibular anterior teeth crowding were involved into conventional group, 22 subjects; low-friction group, 15 subjects; auto-drift group, 12 subjects. The following measurements were performed before treatment (T0) and after alignment (T1): clinical crown

  14. Alveolar process reconstruction after tooth extraction by orthodontic indications

    Directory of Open Access Journals (Sweden)

    Kovalev М.О.

    2013-09-01

    Full Text Available The objective of the study is to determine indications for alveolar bone reconstruction after tooth extraction according to orthodontic indications. Material and methods. 62 patients (first maturity level with dental arch asymmetry due to loss of a premolar on one side of the mouth were examined and treated. Frontal-diagonal coefficient of the dental arch was used to determine the correlation between tooth size and dental arch parameters. Results. It has been demonstrated that changes of the alveolar ridge following the extraction of the first premolars in patients of the experimental group were less significant as compared with the controls. Conclusion. It is reasonable to apply this method simultaneously with the removal of a tooth for orthodontic indications or when the alveolar ridge in the post-extraction socket leaves insufficient bone volume.

  15. Avoiding injury to the inferior alveolar nerve by routine use of intraoperative radiographs during implant placement.

    Science.gov (United States)

    Burstein, Jeffrey; Mastin, Chris; Le, Bach

    2008-01-01

    Injury to the inferior alveolar nerve during implant placement in the posterior atrophic mandible is a rare but serious complication. Although a preoperative computerized tomography scan can help determine the distance from the alveolar ridge to the nerve canal, variables such as magnification errors, ridge anatomy, and operator technique can increase the chance for complications. The routine use of intraoperative periapical radiographs during the drilling sequence is an inexpensive and reliable tool, allowing the operator to confidently adjust the direction and depth of the implant during placement. Most important, it helps avoid the risk of injury to the inferior alveolar nerve in cases in which there is limited vertical alveolar bone. Using this technique for 21 implants placed in the posterior atrophic mandible, with less than 10 mm of vertical bone to the inferior alveolar nerve canal, the authors observed no incidents of postoperative paresthesia.

  16. Augmentation of residual alveolar bone height with tissue engineering for dental implant placement

    Directory of Open Access Journals (Sweden)

    S M Balaji

    2014-01-01

    Full Text Available The challenge of correcting deficient vertical alveolar height for dental implant placement has been there since dental implants came in to regular clinical placement. The ability of various methods to increase the residual alveolar height has met with varying results. The primary reason is that the techniques were not quite successful in maintaining the required residual alveolar height. Use of Bone Morphogentic Protein, especially rhBMP-2 has been met with high degree of success in deficient vertical alveolar height in a mandibular ridge. The demonstration of this using a case has been presented here.

  17. Localized ridge defect augmentation using human pericardium membrane and demineralized bone matrix

    Directory of Open Access Journals (Sweden)

    Arun Kumar Vidyadharan

    2014-01-01

    Conclusion and Clinical Implications: The results suggested that HP Allograft membrane may be a suitable component for augmentation of localized alveolar ridge defects in conjunction with DBM with bone chips.

  18. The influence of Aloe vera and xenograft XCB toward of bone morpho protein 2 BMP2 expression and amount of osteoblast of alveolar bone induced into tooth extraction sockets Cavia cobaya

    Directory of Open Access Journals (Sweden)

    Utari Kresnoadi

    2014-12-01

    Full Text Available Tooth extraction can cause inflammation leading to alveolar ridge resorption. In addition, prominent ridge has crucial role for making denture su-ccessfully. Thus, socket preservation is needed to prevent greater alveolar ridge resorption. An innovative material, a combination of Aloe vera and xe-nograft (XCB, is then considered as a biogenic stimulator that can reduce inflammation, as a result, the growth of alveolar bone is expected to be impro-ved. This research is aimed to prove whether the mixture of Aloe vera and xenograft can stimulate BMP2 and increase osteoblasts. Forty-eight Cavia co-baya animals were divided into eight groups each of which consisted of six animals. The mandibular incisors of those Cavia cobaya animals were then extracted and filled with PEG as Group Control, XCB as Group XCB, Aloe vera as Group Aloe vera, and a combination of Aloe vera +XCB as Group Aloe vera +XCB. Next, the first four groups were sacrificed seven days after extraction, and the second four groups were sacrificed 30 days after extrac-tion. And then, immunohistochemical and histopathology examinations were conducted to examine BMP2 expression and osteoblasts. Based on the re-sult known that the mixture of Aloe vera and xenograft can increase BMP2 expression and amount of osteoblasts. It can be concluded that the mixture of Aloe vera and xenograft can increase BMP2 expression and amount of osteoblast cel . It can be used as an alternative material to increase the growth of alveolar bone after extraction.

  19. Tissue Engineering for Vertical Ridge Reconstruction.

    Science.gov (United States)

    Patel, Neel; Kim, Beomjune; Zaid, Waleed; Spagnoli, Daniel

    2017-02-01

    This article provides an overview of basic tissue engineering principles as they are applied to vertical ridge defects and reconstructive techniques for these types of deficiencies. Presented are multiple clinical cases ranging from office-based dentoalveolar procedures to the more complex reconstruction of postresection mandibular defects. Several different types of regenerative tissue constructs are presented; either used alone or in combination with traditional reconstructive techniques and procedures, such as maxillary sinus augmentation, Le Fort I osteotomy, and microvascular free tissue transfer. The goal is to also familiarize the reconstructive surgeon to potential future strategies in vertical alveolar ridge augmentation. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Preservación de alveolos postexodoncia mediante el uso de diferentes materiales de injerto: Revisión de la literatura / Post-extraction alveolar ridge preservation using bone graft substitutes: Literature review

    OpenAIRE

    2011-01-01

    Objetivo. El objetivo de este estudio fue el de evaluar la literatura científica internacional que reportara técnicas, resultados clínicos y el proceso de cicatrización ósea de los procedimientos de preservación de alveolos post exodoncia que utilizaran xenoinjertos, aloinjertos y aquellos que permitieran la cicatrización natural del alveolo. Materiales y métodos. En esta revisión de la literatura, las bases de datos utilizadas fueron Medline/PubMed, Wiley Online Library, OVID, EBSCO, Scie...

  1. [Distraction osteogenesis of deficient alveolar bone prior to dental rehabilitation].

    Science.gov (United States)

    Shilo, D; Emodi, O; Aizenbud, D; Rachmiel, A

    2015-07-01

    Implant supported rehabilitation has become very common in treatment plans nowadays, yet many patients lack the vertical and horizontal bone dimensions required for endosseous implant insertion. Distraction osteogenesis is a technique in which bone is generated by progressive elongation of two bone fragments following an osteotomy or corticotomy. Distraction osteogenesis of the alveolar ridge as a treatment modality in implant dentistry is a very useful technique that allows for adequate bone formation suitable for implant insertion. Alveolar distraction can be unidirectional, bidirectional, multidirectional or horizontal. Alveolar distraction osteogenesis can be performed by using intraosseous distraction devices, intraosseous distraction implants or by extraosseous devices which are the most prevalent today. Distraction osteogenesis has many advantages such as gradual lengthening of the bone with no need for an autogenous bone graft and lack of the associated donor site morbidity as well as distraction of the surrounding soft tissue together with the transported bone. One of the major challenges when using alveolar distraction osteogenesis is controlling the vector of distraction, this problem should be further addressed in future researches. We describe different methods for alveolar distraction osteogenesis, including the surgical procedure, latency period, lengthening and consolidation period. We also discuss the advantages, disadvantages and complications of the method. In this manuscript a case of mandibular alveolar deficiency following mandibular fracture and loss of teeth and the alveolar bone is presented. This patient was treated by alveolar distraction osteogenesis with excellent results. This patient was later rehabilitated . using endosseous implants as demonstrated by radiographs. Alveolar distraction osteogenesis provides a method to regain both hard tissue and soft tissue without additional grafting and is an efficient modality in cases of medium

  2. Preserving the socket dimensions with bone grafting in single sites: an esthetic surgical approach when planning delayed implant placement.

    Science.gov (United States)

    Irinakis, Tassos; Tabesh, Moe

    2007-01-01

    Recent advancements in barrier membranes, bone grafting substitutes, and surgical techniques have led to a predictable arsenal of treatment methods for clinicians who practice implant dentistry. The contemporary clinician is supplied with proven knowledge, substantiated materials, and instrument inventory that allows implant placement in cases that used to be reserved for the specialist in the past because of their complexity. Nowadays, postextraction alveolar ridge maintenance can be a predictable procedure and can certainly aid the clinician in preventing ridge collapse, thereby allowing for implant placement in a position that satisfies esthetics and function. Extraction socket maintenance for future implant therapy does not rule out immediate implant placement but rather provides an additional option when treatment planning implant patients. This article will focus on the concept of extraction socket preservation using regenerative materials. It will describe a technique suggested by the authors to resist bone resorption and soft tissue shrinkage following tooth extraction.

  3. 3D-CT evaluation of secondary alveolar bone grafts in alveolar clefts

    Energy Technology Data Exchange (ETDEWEB)

    Naitoh, Hiroshi; Nishimura, Yoshihiko [Kyoto Univ. (Japan). Graduate School of Medicine; Yamawaki, Yoshiroh [Kyoto Katsura Hospital (Japan); Morimoto, Naoki [Kobe City General Hospital (Japan)

    2002-07-01

    From 1994 to 2000, we treated 116 patients with cleft alveolus by secondary alveolar bone grafts, and 48 of them were evaluated morphologically with 3D-CT. The frequency of successful bony bridging was significantly higher in the group whose grafts were completely enveloped (including the anterior alveolar ridge) with a mucoperiosteal flap. The frequency was also significantly higher in the group who underwent bone grafts at the age of 13 or less, and canine eruptions did not influence the ratio. Some cases showed such an improved growth pattern of grafted bone that the shape of the affected maxilla resembled that of the normal side, after long-term follow-up observations. The growth increment was remarkable in anterior maxillary height. Orthodontic management guides the canine or incisor into the reconstructed area of the previous cleft. We surmise that the new occlusal position puts pressure on the grafted bone and promotes further osteogenesis. These findings show that it is important to produce sufficient bony bridge to guide the canine or incisor, not the volume of grafted bone, in secondary alveolar bone grafts. Long-term follow-up observation, after more than 2-3 years, is also necessary to evaluate secondary alveolar bone grafts. (author)

  4. 去蛋白牛骨基质与可吸收胶原膜的磨牙拔牙位点保存效果影像学评价%Radiographic evaluation of ridge preservation after molar tooth extraction:a con-trolled clinical trial

    Institute of Scientific and Technical Information of China (English)

    詹雅琳; 胡文杰; 甄敏; 徐涛; 路瑞芳

    2015-01-01

    目的:与自然愈合比较,观察存在骨缺损的磨牙拔牙同期植入去蛋白牛骨基质( Bio-Oss®)并覆盖可吸收胶原膜( Bio-Gide®)愈合6个月后牙槽骨高度和宽度的变化。方法:16名患者共18颗因牙周病变拔除的磨牙纳入本研究,分为对照组(牙齿拔除后自然愈合组)和试验组(应用去蛋白牛骨基质与可吸收胶原膜拔牙位点保存组)。术后即刻及术后6个月拍摄平行投照根尖片和锥束计算机体层摄影术( cone-beam computed tomography , CBCT )检查,通过根尖片和CBCT测量评价术后6个月牙槽骨高度和宽度的变化。结果:术后6个月试验组中央和远中颊侧的牙槽骨高度分别增加2.90 mm 和1.45 mm,而对照组中央和远中颊侧的牙槽骨高度分别降低1.00 mm和1.45 mm,两组间差异有统计学意义(P<0.05),但两组骨宽度变化的差异无统计学意义(P>0.05)。结论:存在骨缺损的磨牙应用去蛋白牛骨基质与可吸收胶原膜进行拔牙位点保存,可明显增加颊侧牙槽骨高度和牙槽嵴顶根方1 mm和4 mm处牙槽骨宽度。%Objective:To compare the bone dimensional changes following tooth extraction alone with extraction plus ridge preservation ( using deproteinized boving bone mineral Bio-Oss® and bioresorbable collagen mambrane Bio-Gide®) in periodontal compromised extraction sockets .Methods: Eighteen molars of sixteen subjects requiring tooth extraction because of periodontal destruction were enrolled in this study .The subjects were assigned to the control group ( extraction alone , EXT) or to the test group ( ridge-preservation procedure with Bio-Oss® and Bio-Gide®, RP) .Parallel periapical X-rays and cone-beam computed tomography ( CBCT ) scans were taken immediately after tooth extraction alone or plus ridge-preservation ( baseline ) and 6 months later .The changes of horizontal ridge width and vertical ridge height were

  5. Pulmonary alveolar proteinosis

    Directory of Open Access Journals (Sweden)

    B. Crestani

    2011-06-01

    Full Text Available Pulmonary alveolar proteinosis (PAP is a rare pulmonary disease characterised by alveolar accumulation of surfactant. It may result from mutations in surfactant proteins or granulocyte macrophage-colony stimulating factor (GM-CSF receptor genes, it may be secondary to toxic inhalation or haematological disorders, or it may be auto-immune, with anti-GM-CSF antibodies blocking activation of alveolar macrophages. Auto-immune alveolar proteinosis is the most frequent form of PAP, representing 90% of cases. Although not specific, high-resolution computed tomography shows a characteristic “crazy paving” pattern. In most cases, bronchoalveolar lavage findings establish the diagnosis. Whole lung lavage is the most effective therapy, especially for auto-immune disease. Novel therapies targeting alveolar macrophages (recombinant GM-CSF therapy or anti-GM-CSF antibodies (rituximab and plasmapheresis are being investigated. Our knowledge of the pathophysiology of PAP has improved in the past 20 yrs, but therapy for PAP still needs improvement.

  6. Clinical application of site preservation in posterior area in order to prevent alveolar bone resorption after tooth extraction%应用位点保存技术预防拔牙后牙槽骨吸收的临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    李景辉; 杨瑛; 张方明

    2016-01-01

    目的:观察和评价应用位点保存技术预防拔牙后牙槽骨吸收的临床疗效。方法选取需要拔除下颌磨牙的患者40例,随机分为两组。实验组20例患者拔牙后即刻在拔牙窝内植入 Bio - Oss骨粉,创口表面覆盖 Bio -Gide胶原膜,对照组20例患者拔牙后进行常规处理。定期复查观察两组患者拔牙窝愈合情况,于拔牙后即刻与拔牙后6个月拍摄锥形束 CT(CBCT),观察和测量牙槽骨垂直向吸收量、牙槽骨高度与宽度、骨密度和新骨轮廓的变化,评价位点保存的临床效果。结果拔牙后6个月实验组牙槽骨垂直向吸收量明显小于对照组;实验组骨密度、新骨轮廓明显优于对照组,两组之间具有统计学差异( P <0.05)。CBCT 测量统计学分析后证实两组间牙槽骨高度与宽度的变化具有显著性差异( P <0.05)。结论位点保存技术可以有效减少因拔牙而造成的牙槽骨吸收,很好地维持拔牙位点的骨量,从而为后期的种植牙修复提供良好的位点条件,值得临床推广。%Objective To observe the clinical effect of site preservation in posterior area in order to prevent alveolar bone resorption after tooth extraction. Methods Forty patients with posterior sick teeth were selected for this study,and they were randomly divided into two groups, 20 patients in trial group were implanted with Bio - Oss in the alveolar socket immediately after tooth extraction,the wound surface covered by Bio- Gide collagen membrane,and the tooth extraction in 20 patients of control group had been performed by conventional treatment. The results of patients in these two groups were observed The changes in alveolar bone density,height,width and new bone contour were observed by CBCTscan-ning in patients of these 2 groups after 6 months. Results In comparison with these two groups,new bone contour and bone density in patients of trial group were significantly

  7. Management of maxillary alveolar process fractures

    Directory of Open Access Journals (Sweden)

    Shukhrat Boymuradov

    2011-04-01

    Full Text Available Incidence of maxillofacial traumas is reported steadily increasing, maxillary fractures being extremely severe. Maxillary alveolar process (AP and front teeth are traumatized more frequently than any other parts of the maxilla. Deprivation of teeth and AP post-traumatic flaw as well as loss of alveolar height not only create a cosmetic defect but also complicate subsequent prosthetics of the patients. The work was initiated to assess efficacy of “CollapAn L” in comparison with a combination of “Osteon”, an osteoplastic material, and “Colla Guide” resorbable membrane in prevention of AP post-traumatic flaws and deformities. 60 patients aged from 16 to 47 with the comminuted fractures of maxillary AP emergently hospitalized were examined and treated. The findings showed that Combination of “Osteon” and “Colla Guide” resorbable membrane is the one to increase efficacy of the treatment, facilitating preservation of and alveolar crest height and shape. In addition, preservation of bone tissue mineralization helps avoid risk of the bone wound inflammatory morbidity.

  8. Pulmonary alveolar microlithiasis

    Directory of Open Access Journals (Sweden)

    Surender Kashyap

    2013-01-01

    Full Text Available Pulmonary alveolar microlithiasis (PAM is a rare, chronic lung disease with bilateral intra-alveolar calcium and phosphate deposition throughout the lung parenchyma with predominance to lower and midzone. Although, etiology and pathogenesis of PAM is not fully understood, the mutation in SLC34A2 gene that encodes a sodium-phosphate co-transporter in alveolar type II cells resulting in the accumulation and forming of microliths rich in calcium phosphate (due to impaired clearance are considered to be the cause of the disease. Chest radiograph and high-resolution CT of thorax are nearly pathognomonic for diagnosing PAM. HRCT demonstrates diffuse micronodules showing slight perilobular predominance resulting in calcification of interlobular septa. Patients with PAM are asymptomatic till development of hypoxemia and cor-pulmonale. No therapy has been proven to be beneficial except lung transplantation.

  9. New ridge parameters for ridge regression

    Directory of Open Access Journals (Sweden)

    A.V. Dorugade

    2014-04-01

    Full Text Available Hoerl and Kennard (1970a introduced the ridge regression estimator as an alternative to the ordinary least squares (OLS estimator in the presence of multicollinearity. In ridge regression, ridge parameter plays an important role in parameter estimation. In this article, a new method for estimating ridge parameters in both situations of ordinary ridge regression (ORR and generalized ridge regression (GRR is proposed. The simulation study evaluates the performance of the proposed estimator based on the mean squared error (MSE criterion and indicates that under certain conditions the proposed estimators perform well compared to OLS and other well-known estimators reviewed in this article.

  10. 两种骨代材料引导组织再生用于牙槽嵴保存的可行性%Feasibility of guided bone tissue regeneration technique to conserve the alveolar ridge: Two kinds of bone substitutes

    Institute of Scientific and Technical Information of China (English)

    高晓蔚; 李珂

    2012-01-01

    BACKGROUND: The ideal bone materials for guiding bone tissue regeneration can maximally recover hard and soft tissue morphology of tooth extraction fossa, which are conducive to the success of dental grown. OBJECTIVE: To compare the effects of different guided bone tissue materials on extraction socket in early reconstruction. METHODS: A total of 60 patients required the extraction of the teeth, and they were randomly divided into three groups with 20 teeth in each. The teeth were extracted and the different guided bone tissue materials were implanted. Bio-Oss and hydroxyapatite were implanted into the Bio-Oss and hydroxyapatite groups after tooth extraction, and no treatment was done in the control group. RESULTS AND CONCLUSION: The heights of the proximal alveolar bone and the interdental papilla as well as the width of lip to lingua were changed little in the Bio-Oss group, more in the hydroxyapatite group, and most in the control group. It can prove that Bio-oss is the best guided bone tissue material in conserving the alveolar ridge after tooth extraction.%背景:理想的骨引导材料可最大程度地恢复拔牙窝处软硬组织形态,利于牙体种植的成功.目的:比较不同骨代材料恢复和重建拔牙窝处软硬组织的能力.方法:纳入2010-01/2011-01 于新疆医科大学第五附属医院口腔颌面外科拔除前牙或前磨牙的60 例患者,随机分为3 组,Bio-Oss 组和羟基磷灰石组于拔牙后分别应用Bio-Oss、羟基磷灰石对拔牙窝进行填充,空白对照组拔牙后不进行任何干预.结果与结论:分别于拔牙前及拔牙后6 个月测量各组邻面牙槽嵴高度、牙间乳头高度及唇舌向宽度,经比较发现,Bio-Oss 组各项指标变化最小,羟基磷灰石组次之,空白对照组变化最大.说明Bio-Oss 作为拔牙后牙槽窝的骨代材料能够更好地维持甚至增加牙槽嵴的骨量,促进软组织外形的恢复.

  11. Staged ridge-split evaluated using cone beam computed tomography and peri-implant plastic surgery in the mandibular arch

    OpenAIRE

    Nikhil Vasant Jain; Purva H Shinde; Gaurav R Poplai; Affaf A Gharatkar

    2015-01-01

    Lack of sufficient bone to place an implant at a functionally and an esthetically appropriate position is a common problem, especially in the mandibular posterior region. Narrow edentulous alveolar ridges

  12. Ridge alterations following tooth extraction with and without flap elevation: an experimental study in the dog.

    Science.gov (United States)

    Araújo, Mauricio G; Lindhe, Jan

    2009-06-01

    Different approaches were advocated to preserve or improve the dimension and contour of the ridge following tooth extraction. In some of studies, socket 'flapless extraction' apparently had a successful outcome. The objective of the present experiment was to compare hard tissue healing following tooth extraction with or without the prior elevation of mucosal full-thickness flaps. Five mongrel dogs were used. The two second mandibular premolars ((2)P(2)) were hemi-sected. The mesial roots were retained. By random selection the distal root in one side was removed after the elevation of full-thickness flaps while on the contralateral side, root extraction was performed in a flapless procedure. The soft tissue wound was closed with interrupted sutures. After 6 months of healing, the dogs were euthanized and biopsies were sampled. From each experimental site, four ground sections - two from the mesial root and two from the healed socket - were prepared, stained and examined in the microscope. The data showed that the removal of a single tooth (root) during healing caused a marked change in the edentulous ridge. In the apical and middle portions of the socket site minor dimensional alterations occurred while in the coronal portion of the ridge the reduction of the hard tissue volume was substantial. Similar amounts of hard tissue loss occurred during healing irrespective of the procedure used to remove the tooth was, i.e. flapless or following flap elevation. Tooth loss (extraction) resulted in marked alterations of the ridge. The size of the alveolar process was reduced. The procedure used for tooth extraction - flapless or following flap elevation - apparently did not influence the more long-term outcome of healing.

  13. [Dento-alveolar injuries].

    Science.gov (United States)

    Voorsmit, R A; Kuijpers-Jagtman, A M

    1992-11-01

    Most dento-alveolar traumas can be managed by the dentist-general practitioner. Still, there are some specific injuries which should be treated by dental specialists. Some specific guidelines are given for the combined surgical-orthodontic treatment of fracture of the coronal part of the root, intrusive luxation, abnormal position of the permanent tooth due to traumatic displacement of the deciduous tooth, ankylosis and tooth loss.

  14. Proteinosis alveolar pulmonar

    Directory of Open Access Journals (Sweden)

    Concepción Sánchez Infante

    2011-12-01

    Full Text Available La proteinosis alveolar pulmonar es una enfermedad respiratoria crónica, caracterizada por alteración en el metabolismo del surfactante, lo que determina su acumulación anormal en el espacio alveolar. Es una enfermedad extremadamente rara. Se han reportado solamente 500 casos en la literatura. Se describió por primera vez en 1958. Se presenta un caso de proteinosis alveolar pulmonar en un lactante de 2 meses, con desnutrición proteico energética, que ingresa por dificultad respiratoria e hipoxemia, y, con imágenes radiológicas de tipo retículo-nodulillar, en vidrio deslustrado, en el cual se plantea inicialmente el diagnóstico de bronconeumonía. Ante la evolución desfavorable y no respuesta al tratamiento, se realizó un estudio para descartar enfermedades pulmonares crónicas. El paciente fallece y se confirma el diagnóstico por anatomía patológica. Se realiza una revisión del tema.

  15. Alveolar development and disease.

    Science.gov (United States)

    Whitsett, Jeffrey A; Weaver, Timothy E

    2015-07-01

    Gas exchange after birth is entirely dependent on the remarkable architecture of the alveolus, its formation and function being mediated by the interactions of numerous cell types whose precise positions and activities are controlled by a diversity of signaling and transcriptional networks. In the later stages of gestation, alveolar epithelial cells lining the peripheral lung saccules produce increasing amounts of surfactant lipids and proteins that are secreted into the airspaces at birth. The lack of lung maturation and the associated lack of pulmonary surfactant in preterm infants causes respiratory distress syndrome, a common cause of morbidity and mortality associated with premature birth. At the time of birth, surfactant homeostasis begins to be established by balanced processes involved in surfactant production, storage, secretion, recycling, and catabolism. Insights from physiology and engineering made in the 20th century enabled survival of newborn infants requiring mechanical ventilation for the first time. Thereafter, advances in biochemistry, biophysics, and molecular biology led to an understanding of the pulmonary surfactant system that made possible exogenous surfactant replacement for the treatment of preterm infants. Identification of surfactant proteins, cloning of the genes encoding them, and elucidation of their roles in the regulation of surfactant synthesis, structure, and function have provided increasing understanding of alveolar homeostasis in health and disease. This Perspective seeks to consider developmental aspects of the pulmonary surfactant system and its importance in the pathogenesis of acute and chronic lung diseases related to alveolar homeostasis.

  16. Maintaining space in localized ridge augmentation using guided bone regeneration with tenting screw technology.

    Science.gov (United States)

    Chasioti, Evdokia; Chiang, Tat Fai; Drew, Howard J

    2013-01-01

    Prosthetic guided implant surgery requires adequate ridge dimensions for proper implant placement. Various surgical procedures can be used to augment deficient alveolar ridges. Studies have examined new bone formation on deficient ridges, utilizing numerous surgical techniques and biomaterials. The goal is to develop time efficient techniques, which have low morbidity. A crucial factor for successful bone grafting procedures is space maintenance. The article discusses space maintenance tenting screws, used in conjunction with bone allografts and resorbable barrier membranes, to ensure uneventful guided bone regeneration (GBR) enabling optimal implant positioning. The technique utilized has been described in the literature to treat severely resorbed alveolar ridges and additionally can be considered in restoring the vertical and horizontal component of deficient extraction sites. Three cases are presented to illustrate the utilization and effectiveness of tenting screw technology in the treatment of atrophic extraction sockets and for deficient ridges.

  17. Application of postextraction socket site preservation in implantology%拔牙后牙槽嵴位点保存在口腔种植学中的应用

    Institute of Scientific and Technical Information of China (English)

    杨明德

    2012-01-01

    拔牙后牙槽嵴的高度、宽度以及周围软组织的保存对于缺牙部位进行种植修复有着非常重要的意义.牙齿拔除后,拔牙窝内新生骨一般无法达到原牙槽嵴的水平,唇颊侧骨板受到的损害尤其严重,造成种植体植入时骨量不足.牙槽嵴位点保存的目的是在拔牙后能有效地保存剩余牙槽嵴的高度、宽度以及相应软组织量,为随后的种植手术和修复提供足够的骨量和美学基础.本文对牙槽嵴位点保存技术及相关的移植材料在骨内种植体领域的研究进展作一综述.%The preservation of height and width dimensions and the soft tissue around the postextraction socket is very significant to place an implant. After teeth extraction, the newly formed bone in the alveolar ridge cannot reach the original level in three dimensions, particularly in bone level of the buccal which results in the scarcity of bone when the implants are placed. The purpose of the preservation of the sites of the alveolar ridge and the soft tissue will help maintain height and width dimensions and soft tissue around the alveolar ridge. The method will provide the enough three-dimension capacity of bone and the aesthetic shape. The purpose of this article is to summarize the method and transplantable material of the preservation of the sites of the alveolar ridge and the soft tissue in the field of dental implant.

  18. Long palatal connective tissue rolled pedicle graft with demineralized freeze-dried bone allograft plus platelet-rich fibrin combination: A novel technique for ridge augmentation - Three case reports

    Directory of Open Access Journals (Sweden)

    Pathakota Krishnajaneya Reddy

    2015-01-01

    Full Text Available Replacement of missing maxillary anterior tooth with localized residual alveolar ridge defect is challenging, considering the high esthetic demand. Various soft and hard tissue procedures were proposed to correct alveolar ridge deformities. Novel techniques have evolved in treating these ridge defects to improve function and esthetics. In the present case reports, a novel technique using long palatal connective tissue rolled pedicle graft with demineralized freeze-dried bone allografts (DFDBAs plus Platelet-rich fibrin (PRF combination was proposed to correct the Class III localized anterior maxillary anterior alveolar ridge defect. The present technique resulted in predictable ridge augmentation, which can be attributed to the soft and hard tissue augmentation with a connective tissue pedicle and DFDBA plus PRF combination. This technique suggests a variation in roll technique with DFDBA plus PRF and appears to promise in gaining predictable volume in the residual ridge defect and can be considered for the treatment of moderate to severe maxillary anterior ridge defects.

  19. "Tent-Pole" for Reconstruction of Large Alveolar Defects: A Case Report.

    Science.gov (United States)

    Xiao, Ting; Zhao, Yuyue; Luo, En; Hu, Jian

    2016-01-01

    Severe tridimensional alveolar ridge defects complicate the placement of dental implants, and surgical removal of some oral tumors might not leave adequate bone for dental implant placement. Regenerating an adequate amount of bone vertically and horizontally to achieve a satisfying outcome for well-osseointegrated implants and thus ensure long-term success of implant restoration is challenging. This report describes the clinical feasibility of a simple approach using a screw tent-pole combined with guided bone regeneration to augment complicated tridimensional alveolar ridge defects in a case of extensive bone loss due to maxillary tumor surgery. Titanium screws were arranged in "tented" fashion to provide stable room for bone regeneration. Regenerated bone was achieved and 2 more implants were placed in the regenerated ridge 10 months later, leading to a successful maxillary prosthesis.

  20. A histologic, histomorphometric, and radiographic comparison between two complexes of CenoBoen/CenoMembrane and Bio-Oss/Bio-Gide in lateral ridge augmentation: A clinical trial

    OpenAIRE

    Babak Amoian; Ehsan Moudi; Maryam Seyed Majidi; S. M. Ali Tabatabaei

    2016-01-01

    Background: Several grafting materials have been used for alveolar ridge augmentation. The literature lacks researches to compare CenoBone to other grafting materials. The aim of this study was to compare CenoBone/CenoMembrane complex to Bio-Oss/Bio-Gide complex in lateral alveolar bone augmentation in terms of radiographic, histologic, and histomorphometric parameters. Materials and Methods: In this randomized controlled trial, ten patients who needed lateral ridge augmentation were sele...

  1. 拔牙位点保存延期种植即刻修复一例报道%Delayed dental implantation with immediate prosthesis after extraction socket site preservation:report of one case

    Institute of Scientific and Technical Information of China (English)

    张新风; 王鹏来; 牛文芝; 秦雁雁

    2015-01-01

    拔牙后牙槽嵴的高度、宽度及周围软组织的保存对于缺牙部位进行种植修复有着非常重要的意义.牙齿拔除后,拔牙窝内新生骨一般无法达到原牙槽嵴的水平,唇颊侧骨板受到的损害尤其严重,造成种植体植入时骨量不足.拔牙位点保存的目的是在拔牙窝内植入生物材料,有效地保存剩余牙槽嵴的高度、宽度以及相应软组织量,为随后的种植手术和修复提供足够的骨量和美学基础.本文报道1例拔牙位点保存延期种植即刻修复病例,经3年的临床观察,证实拔牙窝内植入人工骨粉,拉拢缝合,牙槽嵴保存良好,能满足后期种植牙即刻修复的美观与功能要求.%The site preservation of the alveolar ridge height,width and the surrounding soft tissue after tooth extraction has very important significance for the subsequent dental implantation.After tooth extraction,new bone in extraction sockets is generally unable to reach the original alveolar crest level. The labial or buccal bone plate is usually seriously damaged,resulting in the bone deficiency.Site preservation after tooth extraction can effectively save the residual alveolar ridge height,width and the corresponding soft tissue to provide sufficient bone and aesthetic foundation for subsequent implant surgery and restoration.The paper report one case of delayed dental implantation with immediate prosthesis after extraction socket site preservation.It was clinically confirmed the alveolar ridge was well preserved to meet the subsequent dental implantation and immediate restoration,by plugging artificial biomaterials in extraction socket and only sutureing the wound.

  2. Clinical and biometrical evaluation of socket preservation using demineralized freeze-dried bone allograft with and without the palatal connective tissue as a biologic membrane.

    Science.gov (United States)

    Moghaddas, Hamid; Amjadi, Mohammad Reza; Naghsh, Narges

    2012-11-01

    Alveolar ridge preservation following tooth extraction has the ability to maintain the ridge dimensions and allow the implant placement in an ideal position fulfilling both functional and aesthetic results. The aim of this study was to evaluate the efficacy of the palatal connective tissue as a biological membrane for socket preservation with demineralized freeze-dried bone allograft (DFDBA). Twelve extraction sites were treated with DFDBA with (case group) and without (control group) using autogenous palatal connective tissue membrane before placement of implants. Alveolar width and height, amount of keratinized tissue, and gingival level were measured at pre-determined points using a surgical stent at two times, the time of socket preservation surgery. In both groups a decrease in all socket dimensions was found. The average decrease in socket width, height, keratinized tissue, and gingival level in case group was 1.16, 0.72, 3.58, and 1.27 mm, and in control group was 2.08, 0.86, 4.52, and 1.58 mm respectively. Statistical analysis showed that decrease in socket width (P = 0.012), keratinized tissue (P ≤ 0.001), and gingival level (P = 0.031) in case group was significantly lower than that of the control group. Results showed no meaningful difference in socket height changes when compared with case and control groups (P = 0.148). Under the limits of this study, connective tissue membrane could preserve socket width, amount of keratinized tissue, and the gingival level more effectively than DFDBA alone.

  3. Localized ridge augmentation using autogenous block bone graft followed by dental implant placement

    Directory of Open Access Journals (Sweden)

    K V Prabhakara Rao

    2012-01-01

    Full Text Available The placement of endosseous dental implants is often hampered by unfavourable anatomy of the alveolar bone. Most frequently patients lose their teeth due to alveolar bone loss, tooth extraction; trauma and long term use of removable appliances tend to lose the bone making it difficult for the placement of implant in an optimal prosthetic position. The loss of width of the residual alveolar ridge necessitated measures which could refurbish the lost dimensions. Here we report the successful management of such a condition wherein placement of implant was made possible by placement of autogenous bone block graft obtained from the mandibular symphysis region and predictable osseointegration thus achieved.

  4. Alveolar bone grafting

    Directory of Open Access Journals (Sweden)

    Lilja Jan

    2009-10-01

    Full Text Available In patients with cleft lip and palate, bone grafting in the mixed dentition in the residual alveolar cleft has become a well-established procedure. The main advantages can be summarised as follows: stabilisation of the maxillary arch; facilitation of eruption of the canine and sometimes facilitation of the lateral incisor eruption; providing bony support to the teeth adjacent to the cleft; raising the alar base of the nose; facilitation of closure of an oro-nasal fistula; making it possible to insert a titanium fixture in the grafted site and to obtain favourable periodontal conditions of the teeth within and adjacent to the cleft. The timing of the ABG surgery take into consideration not only eruption of the canine but also that of the lateral incisor, if present. The best time for bone grafting surgery is when a thin shell of bone still covers the soon erupting lateral incisor or canine tooth close to the cleft.

  5. The influence of mandibular ridge anatomy on treatment outcome with conventional complete dentures.

    Science.gov (United States)

    Ribeiro, Jaiane A M; de Resende, Camila M B M; Lopes, Ana L C; Farias-Neto, Arcelino; Carreiro, Adriana da F P

    2014-01-01

    Since prognostic indicators are likely to take on increasing importance as a diagnostic tool for selection of patients for implant provision, this study investigated the influence of the shape and resiliency of the mandibular alveolar ridge on the retention and stability of conventional complete dentures. Ninety- three edentulous patients wearing both maxillary and mandibular conventional complete dentures composed the sample. Data were collected regarding shape and resiliencyof the mandibular residual ridge. Dentures were assessed for retention and stability using an objective and reproducible tool.The associations between the clinical characteristics of the mandibular alveolar ridge and denture retention and stability were analyzed using chi-square and Fisher exact tests (a = 0.05). A significant association between ridge shape and denture stability (p denture retention (p complete dentures.

  6. Morphometric Changes of the Socket after Site Preservation Using Nanobone and Collagen Membrane or Stypro Versus Extraction Alone

    Directory of Open Access Journals (Sweden)

    Salahi S

    2015-06-01

    Full Text Available Statement of Problem: The long-term success of a dental implant relies on implant osseointegration into native and viable bone, implant placement in an ideal position, and optimal hard and soft tissue contour. This requires the presence of sufficient alveolar bone volume, good alveolar ridge (Practically with no sign of atrophy and good surgical technique. Objectives: The aim of this randomized controlled clinical study was to evaluate morphometric changes after different alveolar ridge preservation procedures. Materials and Methods: In this study, 33 patients who had single-rooted premolar, which needed to be extracted, were recruited. Patients were randomly divided into 3 groups and after tooth extraction the following treatments were administered: in group A: NanoBone and a collagen membrane; in group B: NanoBone and Stypro; and in group C: natural healing. The following clinical parameters were evaluated at baseline and 6 months after the extraction: buccolingual width, midbuccal height (with the use of a custom made stent and width of keratinized gingiva. For data analysis, Paired t-test,one-way ANOVA and Tukey’s tests were used. Results: The average reduction in the buccolingual width, midbuccal height and keratinized gingiva was as follows: group A: 1.18±0.6, 0.64±0.92 and 3.45±1.75 mm; group B: 2.18±0.75, 0.73±0.78 and 4.73±0.9 mm; and group C: 1±0.89, 2.36±1.21 and 5±0.63 mm, respectively. Moreover, a significantly reduced resorption was found in both the buccolingual width and the width of keratinized gingiva in group A as compared to groups B and C (p<0.05. Conclusions: This study showed that the use of collagen membrane+Nano bone (group A can significantly reduce the horizontal resorption of the alveolar ridge and keratinized tissue more effectively than stypro+Nano bone (group B and blood clot alone and natural healing (group C.

  7. Alveolar inflammation in cystic fibrosis

    DEFF Research Database (Denmark)

    Ulrich, Martina; Worlitzsch, Dieter; Viglio, Simona

    2010-01-01

    BACKGROUND: In infected lungs of the cystic fibrosis (CF) patients, opportunistic pathogens and mutated cystic fibrosis transmembrane conductance regulator protein (CFTR) contribute to chronic airway inflammation that is characterized by neutrophil/macrophage infiltration, cytokine release...... accumulated in type II alveolar epithelial cells, lacking CFTR. P. aeruginosa organisms were rarely present in inflamed alveoli. CONCLUSIONS: Chronic inflammation and remodeling is present in alveolar tissues of the CF lung and needs to be addressed by anti-inflammatory therapies....

  8. Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

    Science.gov (United States)

    Westphalen, Kristin; Gusarova, Galina A.; Islam, Mohammad N.; Subramanian, Manikandan; Cohen, Taylor S.; Prince, Alice S.; Bhattacharya, Jahar

    2014-02-01

    The tissue-resident macrophages of barrier organs constitute the first line of defence against pathogens at the systemic interface with the ambient environment. In the lung, resident alveolar macrophages (AMs) provide a sentinel function against inhaled pathogens. Bacterial constituents ligate Toll-like receptors (TLRs) on AMs, causing AMs to secrete proinflammatory cytokines that activate alveolar epithelial receptors, leading to recruitment of neutrophils that engulf pathogens. Because the AM-induced response could itself cause tissue injury, it is unclear how AMs modulate the response to prevent injury. Here, using real-time alveolar imaging in situ, we show that a subset of AMs attached to the alveolar wall form connexin 43 (Cx43)-containing gap junction channels with the epithelium. During lipopolysaccharide-induced inflammation, the AMs remained sessile and attached to the alveoli, and they established intercommunication through synchronized Ca2+ waves, using the epithelium as the conducting pathway. The intercommunication was immunosuppressive, involving Ca2+-dependent activation of Akt, because AM-specific knockout of Cx43 enhanced alveolar neutrophil recruitment and secretion of proinflammatory cytokines in the bronchoalveolar lavage. A picture emerges of a novel immunomodulatory process in which a subset of alveolus-attached AMs intercommunicates immunosuppressive signals to reduce endotoxin-induced lung inflammation.

  9. Bone changes in ridge split with immediate implant placement: A systematic review

    Directory of Open Access Journals (Sweden)

    Mohamed M. Dohiem

    2015-12-01

    Conclusion: Alveolar ridge splitting might be considered a predictable approach that demonstrates a high implant survival rate, adequate horizontal bone gain and minimal postoperative complications. Weak evidence showed the effect of flap design and immediate implantation on marginal bone loss and survival rate.

  10. Augmentation of localized defects of the anterior maxillary ridge with autogenous bone before insertion of implants

    NARCIS (Netherlands)

    Raghoebar, GM; Batenburg, RHK; Vissink, A; Reintsema, H

    1996-01-01

    Purpose: This study evaluated the applicability of intraorally harvested autogenous bone grafts for the augmentation of the narrow maxillary alveolar ridge to enable insertion of implants for single tooth replacement. Materials and Methods: Local defects of the anterior maxilla were reconstructed in

  11. Ridge and Furrow Fields

    DEFF Research Database (Denmark)

    Møller, Per Grau

    2016-01-01

    Ridge and furrow is a specific way of ploughing which makes fields of systematic ridges and furrows like a rubbing washboard. They are part of an overall openfield system, but the focus in this paper is on the functionality of the fields. There are many indications that agro-technological reasons...

  12. Treatment of sharp mandibular alveolar process with hybrid prosthesis

    Directory of Open Access Journals (Sweden)

    Sukaedi Sukaedi

    2010-09-01

    Full Text Available Background: Losing posterior teeth for a long time would occasionally lead to the sharpening of alveolar process. The removable partial denture usually have problems when used during mastication, because of the pressure on the mucosa under the alveolar ridge. Purpose: The purpose of this case report was to manage patients with sharp mandibular alveolar process by wearing hybrid prosthesis with extra coronal precision attachment retention and soft liner on the surface base beneath the removable partial denture. Case: A 76 years old woman visited the Prosthodontic Clinic Faculty of Dentistry Airlangga University. The patient had a long span bridge on the upper jaw and a free end acrylic removable partial denture on the lower jaw. She was having problems with mastication. The patient did not wear her lower denture because of the discomfort with it during mastication. Hence, she would like to replace it with a new removable partial denture. Case management: The patient was treated by wearing a hybrid prosthesis with extra coronal precision attachment on the lower jaw. Soft liner was applied on the surface of the removable partial denture. Hybrid prosthesis is a complex denture consisting of removable partial denture and fixed bridge. Conclusion: It concluded that after restoration, the patient had no problems with sharp alveolar process with her new denture, and she was able to masticate well.Latar belakang: Kehilangan geligi posterior dapat menimbulkan processus alveolaris tajam. Gigi tiruan sebagian lepasan mempunyai masalah selama pengunyahan karena adanya tekanan di mukosa di bawah alveolar ridge. Tujuan: Tujuan laporan kasus ini adalah untuk menjelaskan cara menangani pasien yang mempunyai prosesus alveolaris yang tajam di rahang bawah dengan dibuatkan protesis hybrid dengan daya tahan extra coronal precision attachment dan soft liner di permukaan bawah basis gigi tiruan sebagian lepasan. Kasus: Pasien wanita berumur 76 tahun datang di klinik

  13. Vertical and horizontal ridge augmentation in anterior maxilla using autograft, xenograft and titanium mesh with simultaneous placement of endosseous implants

    OpenAIRE

    Deshpande, Sudhendra; Deshmukh, Jeevanand; Deshpande, Sumeet; Khatri, Richa; Deshpande, Shubha

    2014-01-01

    Endosseous implants have revolutionized the field of Implants and Periodontics. Implant placement is a viable option in the treatment of partial and full edentulism. However, placement of implants in alveolar deficiencies may lead to adverse angulations, mechanical overload and esthetic dissatisfaction. When minimum dimensions for implant placement are not present in alveolar process, it is necessary to augment the size of the ridge. This can be achieved by various methods and materials. Here...

  14. Pulmonary alveolar microlithiasis with calcified pleural plaques

    Directory of Open Access Journals (Sweden)

    Malhotra Balbir

    2010-01-01

    Full Text Available Pulmonary alveolar microlithiasis (PAM is a rare disease. Herein we report a case of pulmonary alveolar microlithiasis who was suspected to have the disease on chest X-ray and was confirmed on high resolution CT and transbronchial lung biopsy. These investigations showed characteristic features of pulmonary alveolar microlithiasis with diffuse interstitial pulmonary fibrosis.

  15. Distance of the alveolar antral artery from the alveolar crest. Related factors and surgical considerations in sinus floor elevation

    Science.gov (United States)

    Varela-Centelles, Pablo; Loira-Gago, María; Gonzalez-Mosquera, Antonio; Seoane-Romero, Juan M.; Garcia-Martin, José M.

    2016-01-01

    Background In a variable proportion of maxillary sinuses alveolar antral artery is located close to the residual ridge, increasing the chances for haemorrhagic complications during sinus floor elevation procedures. Material and Methods Retrospective observational study of CBCT explorations performed for implant-treatment planning. The upper first molar area was selected for this study. The relative uncertainty (standard deviation of the measurement divided by its mean and expressed as a percentage from 0% to 100%) was chosen for determining the observational errors. For modeling the chances of AAA detection, the generalized additive models (GAM) approach was chosen. Results A total of 240 maxillary sinuses were studied (46.25% males) whose median median age was 58 years old (IQR: 52-66). Univariate models showed that the chances for an AAA-alvelar crest distance ≤15mm increase in wider sinuses with lower, subsinusally edentulous crests. When distance is considered as a continuous variable, the best mutivariate model showed an explained deviance of 67% and included AAA diameter, distance AAA-sinus floor, sinus width, and shape, height and width of the residual ridge. Thinner AAAs are found closer to the crest (within the ≤15mm safe distance). Conclusions Bearing in mind the inclusion criteria and the limitations of this investigation, it is concluded that there is a high proportion of maxillary sinuses where AAA describes a course close to the alveolar crest (≤15mm), which was classically considered a safe distance for SFE. This position is related to the presence of atrophic crests (depressed ridge form) and wide maxillary sinuses where the distance of the vessel to the floor of the sinus is small. This information may permit a better surgical planning of SFE procedures. Key words:Cone-beam computed tomography, blood vessels, sinus floor augmentation, intraoperative complications. PMID:27694790

  16. True Fibroma of Alveolar Mucosa

    Directory of Open Access Journals (Sweden)

    Shankargouda Patil

    2014-01-01

    Full Text Available Benign fibrous overgrowths are often found in the oral cavity, almost always being reactive/irritational in nature. However, benign mesenchymal neoplasms of the fibroblasts are extremely uncommon. Here we report a case of “True Fibroma of Alveolar Mucosa” for its rarity.

  17. Socket preservation using bovine bone mineral and collagen membrane: a randomized controlled clinical trial with histologic analysis.

    Science.gov (United States)

    Cardaropoli, Daniele; Tamagnone, Lorenzo; Roffredo, Alessandro; Gaveglio, Lorena; Cardaropoli, Giuseppe

    2012-08-01

    After tooth extraction, varying amounts of bone resorption occur because of qualitative and quantitative changes at the edentulous site of the alveolar process. The aims of this randomized controlled clinical trial were (1) to compare the postextraction changes in residual ridge dimensions during spontaneous healing with those during socket preservation, (2) to analyze the histologic and histomorphometric aspects of the grafted sockets, and (3) to compare probing procket depth (PPD) and clinical attachment level (CAL) changes at teeth adjacent to extraction sites. Forty-eight teeth were extracted from 41 patients referred for extraction of 1 or more maxillary or mandibular premolars or molars. The edentulous sites were randomly assigned to the control (EXT, extraction alone) or experimental groups (SP, extraction and socket preservation). In the SP group, the sockets were filled with bovine bone mineral and covered with porcine collagen membrane. At baseline and after 4 months, PPD, gingival recession (REC), and CAL were measured at teeth adjacent to the edentulous sites. The changes in ridge dimensions from baseline to 4 months were assessed on dental casts. At 4 months, bone was harvested from the grafted areas in the SP group and the edentulous areas in the EXT group. PPD, REC, and CAL were comparable between groups. However, from baseline to 4 months, the SP group showed significantly less reduction in ridge width (1.04 ± 1.08 mm vs 4.48 ± 0.65 mm, P collagen membrane considerably limits the amount of horizontal and vertical bone resorption when compared with extraction alone.

  18. The axial topographic high at intermediate and fast spreading ridges

    Science.gov (United States)

    Carbotte, Suzanne M.; MacDonald, Ken C.

    1994-12-01

    An axial topographic high is commonly observed at both fast spreading ridges and some segments of intermediate spreading ridges. At fast rates the axial high is primarily created by the buoyancy of hot rock and magma beneath the rise. As newly formed crust is transported off axis, little vestige of an axial high is observed on the ridge flanks. In contrast, at intermediate rates, a significant component of the positive topography may be a volcanic construction, preserved on the ridge flanks as abyssal hills, which are slit axial volcanoes. We suggest this difference in the nature of the axial high reflects a lithosphere strong enough to support construction of a volcanic crestal ridge at intermediate spreading rates, but only rarely at fast rates. Relict overlap ridges, found within the discordant zones left by overlapping spreading centers, is one class of ridge-flank topography which appears to have a significant volcanic constructional component even at fast spreading ridges. Unlike topography away from these discontinuities, the relief and shape of overlapping spreading centers is preserved as relict ridge tips are rafted onto the ridge flanks. Reduced magma supply at these discontinuities may give rise to an axial lithosphere strong enough to support volcanic construction of overlap ridges. Low axial lithospheric strength may also account for the lack of normal faults within the innermost 1-2 km of fast, and some intermediate, spreading ridges. With a thin/weak brittle layer at the ridge crest, tensile failure will predominate and few normal faults will form. Depths to the axial magma chamber reflector observed in multi-channel seismic data limit the thickness of the brittel layer on axis to less than 1-2 km for much of the East Pacific Rise (EPR). This depth is comparable to depths over which tensile failure within the oceanic crust will predominate, estimated from the Griffith criteria for fracture initiation (approx. 0.5-1.5 km). As the brittle layer

  19. Ridge jump process in Iceland

    OpenAIRE

    Garcia, Sebastian

    2010-01-01

    Eastward ridge jumps bring the volcanic zones of Iceland back to the centre of the hotspot in response to the absolute westward drift of the Mid-Atlantic Ridge. Mantellic pulses triggers these ridge jumps. One of them is occurring in Southern Iceland, whereas the exact conditions of the last ridge jump in Northern Iceland remain controversial. The diachronous evolution of these two parts of Iceland may be related to the asymmetric plume-ridge interaction when comparing Northern and Southern I...

  20. Software preservation

    Directory of Open Access Journals (Sweden)

    Tadej Vodopivec

    2011-01-01

    Full Text Available Comtrade Ltd. covers a wide range of activities related to information and communication technologies; its deliverables include web applications, locally installed programs,system software, drivers, embedded software (used e.g. in medical devices, auto parts,communication switchboards. Also the extensive knowledge and practical experience about digital long-term preservation technologies have been acquired. This wide spectrum of activities puts us in the position to discuss the often overlooked aspect of the digital preservation - preservation of software programs. There are many resources dedicated to digital preservation of digital data, documents and multimedia records,but not so many about how to preserve the functionalities and features of computer programs. Exactly these functionalities - dynamic response to inputs - render the computer programs rich compared to documents or linear multimedia. The article opens the questions on the beginning of the way to the permanent digital preservation. The purpose is to find a way in the right direction, where all relevant aspects will be covered in proper balance. The following questions are asked: why at all to preserve computer programs permanently, who should do this and for whom, when we should think about permanent program preservation, what should be persevered (such as source code, screenshots, documentation, and social context of the program - e.g. media response to it ..., where and how? To illustrate the theoretic concepts given the idea of virtual national museum of electronic banking is also presented.

  1. Soft tissue expansion before vertical ridge augmentation: Inflatable silicone balloons or self-filling osmotic tissue expanders?

    Directory of Open Access Journals (Sweden)

    Prasad Vijayrao Dhadse

    2014-01-01

    Full Text Available Recent advances in periodontal plastic surgical procedures allow the clinician to reconstruct deficient alveolar ridges in more predictable ways than previously possible. Placement of implant/s in resorbed ridges poses numerous challenges to the clinician for successful esthetic and functional rehabilitation. The reconstruction frequently utilizes one or combination of periodontal plastic surgical procedures in conjunction with autogenous bone grafting, allogenic bone block grafting, ridge split techniques, distraction osteogenesis, or guided bone regeneration (GBR for most predictable outcomes. Current surgical modalities used in reconstruction of alveolar ridge (horizontal and/or vertical component often involve the need of flap transfer. Moreover, there is compromise in tissue integrity and color match owing to different surgical site and the tissue utilized is insufficient in quantity leading to post surgical graft exposition and/or loss of grafted bone. Soft tissue expansion (STE by implantation of inflatable silicone balloon or self filling osmotic tissue expanders before reconstructive surgery can overcome these disadvantages and certainly holds a promise for effective method for generation of soft tissue thereby achieving predictable augmentation of deficient alveolar ridges for the implant success. This article focuses and compares these distinct tissue expanders for their clinical efficacy of achieving excess tissue that predominantly seems to be prerequisite for ridge augmentation which can be reasonably followed by successful placement of endosseous fixtures.

  2. Effect of Nasal Floor Closure on the Size of Alveolar Cleft in Complete Unilateral or Bilateral Primary Cleft Palate

    Directory of Open Access Journals (Sweden)

    M Moghadaszadeh

    2012-10-01

    Full Text Available Introduction: Cleft lip (CL and cleft palate (CP are among the most common congenital anomalies. Constituting 65% of head and neck anomalies in isolated or syndromic forms, they are considered as the most common head and neck congenital deformities in children. Methods: 15 children from the Tabriz Children Hospital were evaluated in this descriptive-analytic cross sectional study that possessed unilateral and bilateral cleft lip and palate with inclusion criteria. The effect of nasal floor reconstruction on the size of alveolar cleft and palatal anterior fistula formation were evaluated in primary unilateral and bilateral cleft palate. Results: There were 11 (73.3% male and only 4 (26.7% female patients in the sample group. The mean duration from first consult to reconstructive surgery was 3.4±1.8 months (1 to 9 months range. The width of alveolar cleft and alveolar ridge angle on cleft side compared to normal side in sagittal and coronal axis was significant after nasal floor reconstruction (P=0.001, P=0.02, while septal angle changes were not significant (P=0.26, which means no increase in septal deviation has been documented. Conclusion: Considering the significant changes of alveolar cleft width and alveolar ridge angle on cleft side compared to normal side in sagittal and coronal axis after nasal floor closure, this method can be applied as a new interventional surgery in primary unilateral and bilateral cleft palate.

  3. Fingermark ridge drift.

    Science.gov (United States)

    De Alcaraz-Fossoul, Josep; Roberts, Katherine A; Feixat, Carme Barrot; Hogrebe, Gregory G; Badia, Manel Gené

    2016-01-01

    Distortions of the fingermark topography are usually considered when comparing latent and exemplar fingerprints. These alterations are characterized as caused by an extrinsic action, which affects entire areas of the deposition and alters the overall flow of a series of contiguous ridges. Here we introduce a novel visual phenomenon that does not follow these principles, named fingermark ridge drift. An experiment was designed that included variables such as type of secretion (eccrine and sebaceous), substrate (glass and polystyrene), and degrees of exposure to natural light (darkness, shade, and direct light) indoors. Fingermarks were sequentially visualized with titanium dioxide powder, photographed and analyzed. The comparison between fresh and aged depositions revealed that under certain environmental conditions an individual ridge could randomly change its original position regardless of its unaltered adjacent ridges. The causes of the drift phenomenon are not well understood. We believe it is exclusively associated with intrinsic natural aging processes of latent fingermarks. This discovery will help explain the detection of certain dissimilarities at the minutiae/ridge level; determine more accurate "hits"; identify potentially erroneous corresponding points; and rethink identification protocols, especially the criteria of "no single minutiae discrepancy" for a positive identification.

  4. Digital preservation

    CERN Document Server

    Deegan, Marilyn

    2013-01-01

    Digital preservation is an issue of huge importance to the library and information profession right now. With the widescale adoption of the internet and the rise of the world wide web, the world has been overwhelmed by digital information. Digital data is being produced on a massive scale by individuals and institutions: some of it is born, lives and dies only in digital form, and it is the potential death of this data, with its impact on the preservation of culture, that is the concern of this book. So how can information professionals try to remedy this? Digital preservation is a complex iss

  5. Alveolar hypoventilation treated with medroxyprogesterone.

    OpenAIRE

    Milerad, J.; Lagercrantz, H; Löfgren, O.

    1985-01-01

    Two children aged 1 and 20 months developed alveolar hypoventilation syndrome. They suffered severe apnoeic episodes and periodically required assisted ventilation. Their ventilatory response to carbon dioxide was lower than that of normal children and the transcutaneous oxygen tension during sleep was well below the normal range. Treatment with medroxyprogesterone acetate resulted in an improved response to carbon dioxide, and assisted ventilation was no longer needed. Oxygen and carbon diox...

  6. Intraosseous schwannoma originating in inferior alveolar nerve: a case report.

    Science.gov (United States)

    Suga, Kenichiro; Ogane, Satoru; Muramatsu, Kyotaro; Ohata, Hitoshi; Uchiyama, Takeshi; Takano, Nobuo; Shibahara, Takahiko; Eguchi, Jun; Murakami, Satoshi; Matsuzaka, Kenichi

    2013-01-01

    Schwannomas (neurilemmomas) are benign neoplasms derived from Schwann cells of the neurilemma and appear most frequently on the auditory nerve or peripheral nerves of the skin. They arise in the oral and maxillofacial region infrequently, and very rarely in the center of the jaw. We herein present a case of a rare mandibular intraosseous schwannoma derived from the main trunk of the inferior alveolar nerve in a 33-year-old man. Fusiform expansion in the mandibular canal was observed and a mass showing the target sign in the mandibular canal was confirmed on T2-weighted and Gd contrastenhanced T1-weighted MRI. Based on these findings, an inferior alveolar nerve-derived schwannoma or other benign nervous system neoplasm was diagnosed. A buccal side cortical bone flap in the mandibular molar region was removed to expose the mass, which was then peeled away from the nerve fibers and completely removed. Some inferior alveolar nerve fibers that were connected to the mass were removed at the same time, but the remaining nerve fiber bundle was preserved. Histopathology confirmed the diagnosis of a schwannoma with Antoni type A and Antoni type B regions. Although the patient experienced extremely mild paresthesia in the skin over the mental region and mental foramen at immediately after surgery, this had almost entirely disappeared at 7 years and 4 months later, and there has been no tumor recurrence.

  7. Alveolar Macrophage Polarisation in Lung Cancer

    Directory of Open Access Journals (Sweden)

    Saleh A. Almatroodi

    2014-01-01

    Full Text Available The role of alveolar macrophages in lung cancer is multifaceted and conflicting. Alveolar macrophage secretion of proinflammatory cytokines has been found to enhance antitumour functions, cytostasis (inhibition of tumour growth, and cytotoxicity (macrophage-mediated killing. In contrast, protumour functions of alveolar macrophages in lung cancer have also been indicated. Inhibition of antitumour function via secretion of the anti-inflammatory cytokine IL-10 as well as reduced secretion of proinflammatory cytokines and reduction of mannose receptor expression on alveolar macrophages may contribute to lung cancer progression and metastasis. Alveolar macrophages have also been found to contribute to angiogenesis and tumour growth via the secretion of IL-8 and VEGF. This paper reviews the evidence for a dual role of alveolar macrophages in lung cancer progression.

  8. [Persistent dento-alveolar pain disorder (PDAP)].

    Science.gov (United States)

    Warnsinck, C J; Koutris, M; Shemesh, H; Lobbezoo, F

    2015-02-01

    Dento-alveolar pain is common in the orofacial area. Persistent dento-alveolar pain could be experienced without an identifiable etiology with poor response to existing treatments. Confusion about the diagnosis and classification of persistent dento-alveolar pain (PDAP) disorders could explain the difficulties in treatment and unfavorable prognosis. Recently, initial steps were made to improve the taxonomy and diagnostic criteria for PDAP in order to improve clinical research and care.

  9. Digital Preservation.

    Science.gov (United States)

    Yakel, Elizabeth

    2001-01-01

    Reviews research on digital preservation issues, including born-digital and digitally recreated documents. Discusses electronic records research; metadata and other standards; electronic mail; Web-based documents; moving images media; selection of materials for digitization, including primary sources; administrative issues; media stability…

  10. Ridge preservation with the use of deproteinized bovine bone mineral.

    Science.gov (United States)

    Lindhe, Jan; Cecchinato, Denis; Donati, Mauro; Tomasi, Cristiano; Liljenberg, Birgitta

    2014-07-01

    The aim was to examine the tissue composition of extraction sockets that had been grafted with deproteinized bovine bone mineral and allowed to heal for 6 months. Twenty-five subjects with one tooth each scheduled for extraction and replacement with dental implants were recruited. The assigned teeth were carefully removed. The site/patient was thereafter allocated to a test or a control group. In the test group patients, Bio-Oss(®) Collagen was placed to fill the fresh extraction socket while in the controls no grafting was performed. After about 6 months of healing, a biopsy was sampled from the center of the extraction site. The specimens were decalcified, embedded in paraffin, sectioned, and stained in HTX. The proportions occupied by mineralized bone, osteoid, bone marrow, fibrous tissue, and Bio-Oss(®) particles were determined by morphometric point counting. Mineralized bone made up 57.4 ± 12.4% of the control sites (C) and 48.9 ± 8.5% of the T1 sites (graft material not included). The amount of bone marrow (C: 7.1 ± 6.1%, T1: 2.1 ± 3.1%) and osteoid (C: 7.3 ± 4.9%, T1: 1.9 ± 2.1%) was about five times greater in the control than in the test sites. Fibrous tissue comprised 23.1 ± 16.3% (C) and 40.0 ± 11.9% (T1). I n the T2 sites (graft material included), the percentage mineralized bone was 39.9 ± 8.6 while the proportions of bone marrow and osteoid were 1.8 ± 2.5% and 1.6 ± 1.8%. Fibrous tissue occupied 32.4 ± 9.2% and Bio-Oss(®) particles 19.0 ± 6.5% of the T2 sites. Placement of the biomaterial in the fresh extraction socket retarded healing. The Bio-Oss(®) particles were not resorbed but became surrounded by new bone. This may explain why grafted extraction sites may fail to undergo dimensional change. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

  11. Pulmonary alveolar proteinosis in a cat

    NARCIS (Netherlands)

    Szatmári, Viktor; Teske, Erik; Nikkels, Peter G J; Griese, Matthias; de Jong, Pim A; Grinwis, Guy; Theegarten, Dirk; Veraa, Stefanie; van Steenbeek, Frank G; Drent, Marjolein; Bonella, Francesco

    2015-01-01

    BACKGROUND: Pulmonary alveolar proteinosis is an extremely rare lung disease in animals and humans. It is characterized by the deposition of a large amount of phospholipoproteinaceous material in the alveoli. There are several possible etiologies, both congenital and acquired. Alveolar macrophages

  12. Pulmonary alveolar proteinosis in a cat

    NARCIS (Netherlands)

    Szatmári, Viktor; Teske, Erik; Nikkels, Peter G J; Griese, Matthias; de Jong, Pim A; Grinwis, Guy; Theegarten, Dirk; Veraa, Stefanie; van Steenbeek, Frank G; Drent, Marjolein; Bonella, Francesco

    2015-01-01

    BACKGROUND: Pulmonary alveolar proteinosis is an extremely rare lung disease in animals and humans. It is characterized by the deposition of a large amount of phospholipoproteinaceous material in the alveoli. There are several possible etiologies, both congenital and acquired. Alveolar macrophages p

  13. Intracranial alveolar echinococcosis: CT and MRI

    Energy Technology Data Exchange (ETDEWEB)

    Bensaid, A.H. (Dept. of Radiology B, Univ. Hospital, Strasbourg (France)); Dietemann, J.L. (Dept. of Radiology B, Univ. Hospital, Strasbourg (France)); Filippi de la Palavesa, M.M. (Dept. of Radiology B, Univ. Hospital, Strasbourg (France)); Klinkert, A. (Dept. of Radiology B, Univ. Hospital, Strasbourg (France)); Kastler, B. (Dept. of Radiology B, Univ. Hospital, Strasbourg (France)); Gangi, A. (Dept. of Radiology B, Univ. Hospital, Strasbourg (France)); Jacquet, G. (Dept. of Neurosurgery, Univ. Hospital, Besancon (France)); Cattin, F. (Dept. of Radiology, Univ. Hospital, Besancon (France))

    1994-05-01

    Intracranial alveolar echinococcosis is uncommon. We report a patient with right frontal lobe and palpebral lesions secondary to a primary hepatic focus with secondary lesion in the lung. The intracranial and palpebral cystic masses were totally removed and both proved to be alveolar hydatid cysts. An unusual feature in this case is CT and MRI demonstration of dural and bony extension. (orig.)

  14. Pulmonary alveolar microlithiasis in children

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, H. [Center of Diagnostic Radiology, Frankfurt Univ. (Germany); Loercher, U. [Center of Diagnostic Radiology, Frankfurt Univ. (Germany); Kitz, R. [Center of Pediatrics, Frankfurt Univ. (Germany); Zielen, S. [Center of Pediatrics, Frankfurt Univ. (Germany); Ahrens, P. [Center of Pediatrics, Frankfurt Univ. (Germany); Koenig, R. [Inst. of Human Genetics, Frankfurt Univ. (Germany)

    1996-01-01

    Two asymptomatic Turkish sibs are presented, a 4-year-old boy and his 7-year-old sister, with pulmonary alveolar microlithiasis (PAM) confirmed by transbronchial lung biopsy and bronchoalveolar lavage. Chest radiographs and high resolution CT demonstrated wide-spread intra-alveolar calcifications in both lungs. The lesions were sharply defined and less than 1 mm in diameter. CT documented a high concentration of microliths along the bronchovascular bundles, the intralobular fissue and the (sub)pleural lung parenchyma. The combination of bronchoalveolar lavage and roentgenographic appearance in high resolution CT are characteristic and pathognomonic, and can confirm the diagnosis. The more severe changes in the elder sib and the radiographic controls suggest that the pulmonary disease may be progressive in our patients. The described family of consanguineous, unaffected parents with two affected and one healthy child confirmed the autosomal recessive inheritance of PAM (McKusick 265100). In addition, the affected girl had autosomal recessive Waardenburg-anophthalmia syndrome (McKusick 206920), raising the question of whether this is a chance occurrence or possibly a contiguous gene syndrome. (orig.)

  15. Modified ridge splitting technique using conical space maintainers for delayed implant placement in highly atrophic maxillae.

    OpenAIRE

    Cabanes Gumbau, Guillermo; Silvestre Donat, Francisco Javier

    2010-01-01

    Background: A low-morbidity surgical technique is described for the horizontal augmentation of highly atrophic alveolar ridges in which first surgical step implant placement is contraindicated. The aim of this case report was to present an alternative treatment for the rehabilitation of the atrophic maxilla. Methods: The technique involves a crestal corticotomy with transverse expansion of the vestibular and lingual cortical layers, followed by the placement of threaded titaniu...

  16. Oral and dental restoration of wide alveolar cleft using distraction osteogenesis and temporary anchorage devices.

    Science.gov (United States)

    Rachmiel, Adi; Emodi, Omri; Gutmacher, Zvi; Blumenfeld, Israel; Aizenbud, Dror

    2013-12-01

    Closure of large alveolar clefts and restoration by a fixed bridge supported by implants is a challenge in cleft alveolus treatment. A major aesthetic concern with distraction osteogenesis is obtaining a predictable position of the implant in relation to the newly generated bony alveolar ridge. We describe the treatment of a large cleft alveolus and palate reconstruction by distraction osteogenesis utilizing temporary anchorage devices (TADs) followed by a fixed implant-supported bridge. The method consists of segmental bone transport by distraction osteogenesis using a bone-borne distractor to minimize the alveolar cleft, followed by closure of the residual small defect by bone grafting three months later. During the active transport distraction, TADs were used exerting multidirectional forces to control the distraction vector forward and laterally for better interarch relation. A vertical alveolar distraction of the newly reconstructed bone of 15 mm facilitated optimal implant placement. The endosseous implants were osteointegrated and supported a fixed dental prosthesis. In conclusion, the large cleft alveolus defect was repaired in three dimensions by distraction osteogenesis assisted by TADs, and the soft tissues expanded simultaneously. Endosseous implants were introduced in the newly reconstructed bone for a fixed dental prosthesis enabling, rehabilitation of aesthetics, eating and speaking.

  17. Barrier-protective effects of activated protein C in human alveolar epithelial cells.

    Directory of Open Access Journals (Sweden)

    Ferranda Puig

    Full Text Available Acute lung injury (ALI is a clinical manifestation of respiratory failure, caused by lung inflammation and the disruption of the alveolar-capillary barrier. Preservation of the physical integrity of the alveolar epithelial monolayer is of critical importance to prevent alveolar edema. Barrier integrity depends largely on the balance between physical forces on cell-cell and cell-matrix contacts, and this balance might be affected by alterations in the coagulation cascade in patients with ALI. We aimed to study the effects of activated protein C (APC on mechanical tension and barrier integrity in human alveolar epithelial cells (A549 exposed to thrombin. Cells were pretreated for 3 h with APC (50 µg/ml or vehicle (control. Subsequently, thrombin (50 nM or medium was added to the cell culture. APC significantly reduced thrombin-induced cell monolayer permeability, cell stiffening, and cell contraction, measured by electrical impedance, optical magnetic twisting cytometry, and traction microscopy, respectively, suggesting a barrier-protective response. The dynamics of the barrier integrity was also assessed by western blotting and immunofluorescence analysis of the tight junction ZO-1. Thrombin resulted in more elongated ZO-1 aggregates at cell-cell interface areas and induced an increase in ZO-1 membrane protein content. APC attenuated the length of these ZO-1 aggregates and reduced the ZO-1 membrane protein levels induced by thrombin. In conclusion, pretreatment with APC reduced the disruption of barrier integrity induced by thrombin, thus contributing to alveolar epithelial barrier protection.

  18. Ridge alterations following grafting of fresh extraction sockets in man. A randomized clinical trial.

    Science.gov (United States)

    Araújo, Mauricio G; da Silva, João Carlos Costa; de Mendonça, Arthur Furtado; Lindhe, Jan

    2015-04-01

    To evaluate dimensional alterations of the alveolar ridge that occurred following tooth extraction at sites grafted with Bio-Oss(®) Collagen. Twenty-eight subjects with maxillary incisors, canines, and premolars scheduled for extraction were included. The tooth was carefully removed. The patients were randomly assigned to a test or a control group. In the test group patients, Bio-Oss(®) Collagen was placed in the fresh extraction socket while in the controls no grafting was performed. Radiographic examination (cone beam computed tomograms, CBCT) was performed immediately after tooth extraction and socket treatment. Four months later, a new CBCT was obtained. In the radiographs, (i) the distance (mm) between base of the alveolar process (apex) and the buccal and palatal crests was determined, (ii) the outer profile of alveolar process of the experimental sites was outlined, and the cross section of the area (mm(2) ) determined. After 4 months of healing, the buccal and to a less extent also the palatal bone plate had become markedly reduced in height. The placement of a biomaterial in the socket failed to prevent resorption of the buccal and palatal bone walls. The cross-sectional area of the control ridge was reduced about 25% and of the test ridge with 3%. The placement of a xenograft in fresh extraction sockets markedly counteracted the reduction in the hard tissue component of the edentulous sites. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. Preserving Chile

    OpenAIRE

    Brennand, Charlotte P.

    2010-01-01

    The best way to preserve chile depends on how you plan to use it and your available storage space. Frozen or canned chile is best for chile rellenos and salsas. Stews can use frozen, canned or dried chile. Dried chile has minimal storage requirements and is light-weight for taking on camping trips. Pickled chiles can be used on a relish plate or as an ingredient in other dishes.

  20. Post-extraction application of beta-tricalcium phosphate in alveolar socket

    Directory of Open Access Journals (Sweden)

    M. Muñoz-Corcuera

    2015-03-01

    Full Text Available Aim The objective of this study was to assess the capacity of beta-tricalcium phosphate to facilitate bone formation in the socket and prevent post-extraction alveolar resorption. Materials and methods After premolar extraction in 16 patients, the sockets were filled with beta-tricalcium phosphate. Six months later, during the implant placement surgery, a trephine was used to harvest the bone samples which were processed for histological and histomorphometrical analyses. Data were gathered on patient, clinical, histological and histomorphometric variables at the extraction and implant placement sessions, using data collection forms and pathological reports. Results Clinical outcomes were satisfactory, the biomaterial was radio-opaque on X-ray. Histological study showed: partial filling with alveolar bone of appropriate maturation and mineralization for the healing time, osteoblastic activity and bone lacunae containing osteocytes. The biomaterial was not completely resorbed at six months. Conclusion Beta-tricalcium phosphate is a material capable of achieving preservation of the alveolar bone when it is positioned in the immediate post-extraction socket followed by suture; it also helps the formation of new bone in the socket. Further studies are needed comparing this technique with other available biomaterials, with growth factors and with sites where no alveolar preservation techniques are performed.

  1. Initiation of Ridges and Transform Faults

    Science.gov (United States)

    Nyst, M.; Thompson, G. A.; Parsons, T.

    2004-12-01

    No clear consensus has emerged to explain initiation of the strikingly regular pattern of ocean ridges and transform faults. The question is important on the continents also, because a less regular pattern of step-overs on faults such as the San Andreas influences the sources of earthquakes. We explore the question by finite element modeling and a study of observational data on ridges and transforms. We focus on the simplest case, where ridges and transforms seem to self-organize at new plate boundaries as soon as new oceanic (magmatic) crust forms. The South Atlantic supplies a clear example. Continental South America and Africa separated along an irregular break, whose general shape is still preserved in the Mid-Atlantic Ridge. In detail, however, the sea floor magnetic anomalies and satellite gravity show that traces of the ridges and transforms extend to the base of the continental slope, i.e. they formed quickly in the new oceanic crust. The Gulf of California provides another clear example and is notable because of its northward transition into the continental San Andreas fault system. In continental crust, dike segments connected by transform faults provide the clearest analogues of oceanic ridges and transforms. Remarkably, the ridge-transform pattern has been simulated by pulling the crust on molten wax [Oldenburg and Brune, JGR, 80, 1975] and also observed in the crust of a molten lava lake [Duffield, JGR, 77, 1972]. In neither of these models, however, do the spatial and temporal scales permit investigation of the dikes whose repeated emplacement and inflation builds layer 3 of the ocean crust. It is well established that, under a buoyant head of magma, dikes tend to fracture and intrude the crust in planes perpendicular to the least horizontal stress, and they relieve the stress difference as they inflate [e.g. Parsons and Thompson, Science, 253, 1991]. Dikes are commonly used as stress-direction indicators analogous to artificial hydraulic fractures

  2. Preservation Priority

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    China ratified the UNESCO Convention Concerning the Protection of World Cultural and Natural Heritage in 1985. This set the tone for a course of action aimed at protecting the common heritage of mankind in tandem with the international community. Recently, Chao Huashan, a renowned expert on world heritage studies in China, spoke to Beijing Review reporter Zan Jifang, sharing his understanding about the value of the World Heritage Convention and his suggestions for China’s future work on preserving its heritage. Excerpts follow:

  3. Distracción osteogénica. Una alternativa para la reconstrucción de rebordes alveolares en sector mandibular. Meta-análisis

    Directory of Open Access Journals (Sweden)

    Iván Manotas

    2013-10-01

    Full Text Available Title: Distraction osteogenic. An alternative for reconstruction in sector mandibular alveolar ridge. Meta-analysis.ResumenLa distracción osteogénica es una técnica quirúrgica utilizada para la reconstrucción de reborde alveolar, para incrementar cantidades de hueso y tejidos blandos como consecuencia del desplazamiento gradual de fracturas óseas quirúrgicamente realizadas. Como las técnicas de distracción generan hueso nuevo y evitan por tanto la morbilidad del traslado de injertos, se trata de un procedimiento que presenta muchas ventajas en comparación con los otros tipos de tratamientos realizados en esta clase de deformidades óseas. Mediante este artículo de revisión de literatura queremos demostrar que es el tratamiento ideal cuando se trata de reducir la deformidad ósea. (DUAZARY 20112 No. 1, 49 - 59AbstractDistraction osteogenesis is a surgical technique which is used for the reconstruction of the alveolar ridge, to increase amounts of bone and soft tissue due to the gradual displacement of bone fractures surgically performed. Because distraction techniques generate new bone avoids the morbidity of moving grafts, this technique has many advantages over other types of treatment carried out in such bone deformities, which by this article were view literature demonstrate that the treatment issue when it comes to reducing bone deformity.Keywords: Osteogénesis distraction; alveolar ridge augmentation; bone lengthening.

  4. Identification of an Autophagy Defect in Smokers’ Alveolar Macrophages1

    OpenAIRE

    2010-01-01

    Alveolar macrophages are essential for clearing bacteria from the alveolar surface and preventing microbial-induced infections. It is well documented that smokers have an increased incidence of infections, in particular lung infections. Alveolar macrophages accumulate in smokers’ lungs but they have a functional immune deficit. In this study, we identify for the first time an autophagy defect in smokers’ alveolar macrophages. Smokers’ alveolar macrophages accumulate both autophagosomes and p6...

  5. Lung alveolar epithelium and interstitial lung disease.

    Science.gov (United States)

    Corvol, Harriet; Flamein, Florence; Epaud, Ralph; Clement, Annick; Guillot, Loic

    2009-01-01

    Interstitial lung diseases (ILDs) comprise a group of lung disorders characterized by various levels of inflammation and fibrosis. The current understanding of the mechanisms underlying the development and progression of ILD strongly suggests a central role of the alveolar epithelium. Following injury, alveolar epithelial cells (AECs) may actively participate in the restoration of a normal alveolar architecture through a coordinated process of re-epithelialization, or in the development of fibrosis through a process known as epithelial-mesenchymal transition (EMT). Complex networks orchestrate EMT leading to changes in cell architecture and behaviour, loss of epithelial characteristics and gain of mesenchymal properties. In the lung, AECs themselves may serve as a source of fibroblasts and myofibroblasts by acquiring a mesenchymal phenotype. This review covers recent knowledge on the role of alveolar epithelium in the pathogenesis of ILD. The mechanisms underlying disease progression are discussed, with a main focus on the apoptotic pathway, the endoplasmic reticulum stress response and the developmental pathway.

  6. Consideraciones anatomicas del conducto alveolar inferior

    National Research Council Canada - National Science Library

    Ortiz, Yudy Patricia; Camargo Canon, Oscar Andres; Ruge Jimenez, Omar Yamid

    2009-01-01

    ..., las distancias del agujero mentoniano al borde basal y la cresta alveolar. Se hicieron cortes en la rama y el cuerpo, para determinar las relaciones con estructuras anatomicas proximas. Resultados...

  7. Data Preservation

    Directory of Open Access Journals (Sweden)

    Carlo Meghini

    2013-07-01

    Full Text Available Digital information is a vital resource in our knowledge economy, valuable for research and education, science and the humanities, creative and cultural activities, and public policy (The Blue Ribbon Task Force on Sustainable Digital Preservation and Access, 2010. New high-throughput instruments, telescopes, satellites, accelerators, supercomputers, sensor networks, and running simulations are generating massive amounts of data (Thanos, 2011. These data are used by decision makers for improving the quality of life of citizens. Moreover, researchers are employing sophisticated technologies to analyse these data to address questions that were unapproachable just a few years ago (Helbing & Balietti, 2011. Digital technologies have fostered a new world of research characterized by immense datasets, unprecedented levels of openness among researchers, and new connections among researchers, policy makers, and the public (The National Academy of Sciences, 2009.

  8. Power Preservation

    DEFF Research Database (Denmark)

    Galster, Kjeld

    Power Preservation (Abstract) In the 17th century, just as today, coalitions needed ‘lead nations’. This was assumed to be a power with great military and economic potentials, and Denmark endeavoured to act as such a leader in the Thirty Years War from 1626 to 28. The results were not encouraging...... in the military field and they were disastrous as far as fiscal matters were concerned. Sweden took over the leadership of the protestant side and she took over Denmark’s place amongst the great powers of the Baltic Region. From that time onwards, Danish influence and options on the international stage gradually...... declined. Thus, Denmark of the 17th century is not to be counted amongst the great powers, but since Christian V’s accession to the throne in 1670 Denmark-Norway has developed into one of Europe’s most highly militarised states. Apart from a permanently combat ready navy, the country maintains a standing...

  9. Polygonal Ridge Networks on Mars

    Science.gov (United States)

    Kerber, Laura; Dickson, James; Grosfils, Eric; Head, James W.

    2016-10-01

    Polygonal ridge networks, also known as boxwork or reticulate ridges, are found in numerous locations and geological contexts across Mars. While networks formed from mineralized fractures hint at hot, possibly life-sustaining circulating ground waters, networks formed by impact-driven clasting diking, magmatic dikes, gas escape, or lava flows do not have the same astrobiological implications. Distinguishing the morphologies and geological context of the ridge networks sheds light on their potential as astrobiological and mineral resource sites of interest. The most widespread type of ridge morphology is characteristic of the Nili Fossae and Nilosyrtis region and consists of thin, criss-crossing ridges with a variety of heights, widths, and intersection angles. They are found in ancient Noachian terrains at a variety of altitudes and geographic locations and may be a mixture of clastic dikes, brecciated dikes, and mineral veins. They occur in the same general areas as valley networks and ancient lake basins, but they are not more numerous where these features are concentrated, and can appear in places where they morphologies are absent. Similarly, some of the ridge networks are associated with hydrated mineral detections, but some occur in locations without detections. Smaller, light-toned ridges of variable widths have been found in Gale Crater and other rover sites and are interpreted to be smaller version of the Nili-like ridges, in this case formed by the mineralization of fractures. This type of ridge is likely to be found in many other places on Mars as more high-resolution data becomes available. Hellas Basin is host to a third type of ridge morphology consisting of large, thick, light-toned ridges forming regular polygons at several superimposed scales. While still enigmatic, these are most likely to be the result of sediment-filled fractures. The Eastern Medusae Fossae Formation contains large swaths of a fourth, previously undocumented, ridge network type

  10. Distracción osteogénica. Una alternativa para la reconstrucción de rebordes alveolares en sector mandibular. Meta-análisis

    OpenAIRE

    2013-01-01

    Title: Distraction osteogenic. An alternative for reconstruction in sector mandibular alveolar ridge. Meta-analysis.ResumenLa distracción osteogénica es una técnica quirúrgica utilizada para la reconstrucción de reborde alveolar, para incrementar cantidades de hueso y tejidos blandos como consecuencia del desplazamiento gradual de fracturas óseas quirúrgicamente realizadas. Como las técnicas de distracción generan hueso nuevo y evitan por tanto la morbilidad del traslado de injertos, se trata...

  11. Geology along the Blue Ridge Parkway in Virginia

    Science.gov (United States)

    Carter, Mark W.; Southworth, C. Scott; Tollo, Richard P.; Merschat, Arthur J.; Wagner, Sara; Lazor, Ava; Aleinikoff, John N.

    2017-01-01

    Back Formations. These rocks are bound by numerous faults, including the Rock Castle Creek fault that separates Ashe Formation rocks from Alligator Back Formation rocks in the core of the Ararat River synclinorium. The lack of unequivocal paleontologic or geochronologic ages for any of these rock sequences, combined with fundamental and conflicting differences in tectonogenetic models, compound the problem of regional correlation with Blue Ridge cover rocks to the north.The geologic transition from the central to southern Appalachians is also marked by a profound change in landscape and surficial deposits. In central Virginia, the Blue Ridge consists of narrow ridges that are held up by resistant but contrasting basement and cover lithologies. These ridges have shed eroded material from their crests to the base of the mountain fronts in the form of talus slopes, debris flows, and alluvial-colluvial fans for perhaps 10 m.y. South of Roanoke, however, ridges transition into a broad hilly plateau, flanked on the east by the Blue Ridge escarpment and the eastern Continental Divide. Here, deposits of rounded pebbles, cobbles, and boulders preserve remnants of ancestral west-flowing drainage systems.Both bedrock and surficial geologic processes provide an array of economic deposits along the length of the Blue Ridge Parkway corridor in Virginia, including base and precious metals and industrial minerals. However, common stone was the most important commodity for creating the Blue Ridge Parkway, which yielded building stone for overlooks and tunnels, or crushed stone for road base and pavement.

  12. [Cleft lip, alveolar and palate sequelae. Proposal of new alveolar score by the Alveolar Cleft Score (ACS) classification].

    Science.gov (United States)

    Molé, C; Simon, E

    2015-06-01

    The management of cleft lip, alveolar and palate sequelae remains problematic today. To optimize it, we tried to establish a new clinical index for diagnostic and prognostic purposes. Seven tissue indicators, that we consider to be important in the management of alveolar sequelae, are listed by assigning them individual scores. The final score, obtained by adding together the individual scores, can take a low, high or maximum value. We propose a new classification (ACS: Alveolar Cleft Score) that guides the therapeutic team to a prognosis approach, in terms of the recommended surgical and prosthetic reconstruction, the type of medical care required, and the preventive and supportive therapy to establish. Current studies are often only based on a standard radiological evaluation of the alveolar bone height at the cleft site. However, the gingival, the osseous and the cellular areas bordering the alveolar cleft sequelae induce many clinical parameters, which should be reflected in the morphological diagnosis, to better direct the surgical indications and the future prosthetic requirements, and to best maintain successful long term aesthetic and functional results. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  13. Comparison between implants inserted into piezo split and unsplit alveolar crests.

    Science.gov (United States)

    Danza, Matteo; Guidi, Riccardo; Carinci, Francesco

    2009-11-01

    Piezoelectric surgery (PES) uses a modulated ultrasonic frequency that permits highly precise and safe hard tissue cutting. A retrospective study on a series of spiral family implants inserted with or without PES split crest was performed to verify if implants inserted into crests split using PES have a comparable outcome to those inserted into unsplit bone. In the period from May 2004 to November 2007, 86 patients (55 women and 31 men, median age 53 yrs) were operated on and 234 spiral family implants were inserted. Among these, 21 were inserted into PES split crest. Mean follow-up was 13 months (3 to 35 months). The Kaplan-Meier algorithm was used to compare the 2 groups in survival and clinical success (ie, decreased bone resorption around implant neck). Only 9 of 234 implants were lost (ie, survival rate 96.2%), all of which belonged to the unsplit group but no statistical difference was demonstrated. To detect if PES split crest produces a better clinical outcome in comparison with fixtures inserted into unsplit alveolar ridges, crestal bone loss was compared in the remaining loaded implants (234--9 lost--5 not prosthetized = 220). No statistical significant difference was detected by comparing implants inserted into PES split crests with untreated alveolar ridges, although a better trend was visible for fixtures inserted into PES split crests. PES split crests provide several advantages and clinical outcomes that are not worse in terms of bone remodeling, if compared with standard procedures.

  14. Planktic foraminifer census data from Northwind Ridge Core 5, Arctic Ocean

    Science.gov (United States)

    Foley, Kevin M.; Poore, Richard Z.

    1991-01-01

    The U.S. Geological Survey recovered 9 piston cores from the Northwind Ridge in the Canada Basin of the Arctic Ocean from a cruise of the USCGC Polar Star during 1988. Preliminary analysis of the cores suggests sediments deposited on Northwind Ridge preserve a detailed record of glacial and interglacial cycles for the last few hundred-thousand to one million years. This report includes quantitative data on foraminifers and selected sediment size-fraction data in samples from Northwind Ridge core PI-88AR P5.

  15. Ridge 2000 Data Management System

    Science.gov (United States)

    Goodwillie, A. M.; Carbotte, S. M.; Arko, R. A.; Haxby, W. F.; Ryan, W. B.; Chayes, D. N.; Lehnert, K. A.; Shank, T. M.

    2005-12-01

    Hosted at Lamont by the marine geoscience Data Management group, mgDMS, the NSF-funded Ridge 2000 electronic database, http://www.marine-geo.org/ridge2000/, is a key component of the Ridge 2000 multi-disciplinary program. The database covers each of the three Ridge 2000 Integrated Study Sites: Endeavour Segment, Lau Basin, and 8-11N Segment. It promotes the sharing of information to the broader community, facilitates integration of the suite of information collected at each study site, and enables comparisons between sites. The Ridge 2000 data system provides easy web access to a relational database that is built around a catalogue of cruise metadata. Any web browser can be used to perform a versatile text-based search which returns basic cruise and submersible dive information, sample and data inventories, navigation, and other relevant metadata such as shipboard personnel and links to NSF program awards. In addition, non-proprietary data files, images, and derived products which are hosted locally or in national repositories, as well as science and technical reports, can be freely downloaded. On the Ridge 2000 database page, our Data Link allows users to search the database using a broad range of parameters including data type, cruise ID, chief scientist, geographical location. The first Ridge 2000 field programs sailed in 2004 and, in addition to numerous data sets collected prior to the Ridge 2000 program, the database currently contains information on fifteen Ridge 2000-funded cruises and almost sixty Alvin dives. Track lines can be viewed using a recently- implemented Web Map Service button labelled Map View. The Ridge 2000 database is fully integrated with databases hosted by the mgDMS group for MARGINS and the Antarctic multibeam and seismic reflection data initiatives. Links are provided to partner databases including PetDB, SIOExplorer, and the ODP Janus system. Improved inter-operability with existing and new partner repositories continues to be

  16. Perawatan Ortodontik Gigi Anterior Berjejal dengan Tulang Alveolar yang Tipis

    Directory of Open Access Journals (Sweden)

    Miesje K. Purwanegara

    2015-09-01

    Full Text Available Anterior teeth movement in orthodontic treatment is limited to labiolingual direction by very thin alveolar bone. An uncontrolled anterior tooth movement to labiolingual direction can cause alveolar bone perforation at its root segment. This case report is to remind us that alveolar bone thickness limits orthodontc tooth movement. A case of crowded anterior teeth with thin alveolar bone in malocclusion I is reported. This case is treated using adgewise orthodontic appliance. Protraction of anterior teeth is anticipated due to thin alveolar bone on the anterior surface. The conclusion is although the alveolar bone surrounding the crowded anterior teeth is thin, by controlling the movement the teeth reposition is allowed.

  17. Orthopantomographic study of the alveolar bone level on periodontal disease

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ki Sik; You, Dong Soo [College of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    1972-11-15

    The author had measured the alveolar bone level of periodontal disease on 50 cases of orthopantomogram to detect the degree of alveolar bone resorption of both sexes of Korean. The results were obtained as follows; 1. Alveolar bone resorption of mesial and distal portion was similar in same patient. 2. The order of alveolar bone resorption was mandibular anterior region, posterior region, canine and premolar region of both jaws. 3. The degree of alveolar bone destruction was severe in shorter root length than longer one. 4. The degree of alveolar bone resorption was severe in fourth decades.

  18. The Ovariectomized Rat as a Model for Studying Alveolar Bone Loss in Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Bryan D. Johnston

    2015-01-01

    Full Text Available In postmenopausal women, reduced bone mineral density at the hip and spine is associated with an increased risk of tooth loss, possibly due to a loss of alveolar bone. In turn, having fewer natural teeth may lead to compromised food choices resulting in a poor diet that can contribute to chronic disease risk. The tight link between alveolar bone preservation, tooth retention, better nutritional status, and reduced risk of developing a chronic disease begins with the mitigation of postmenopausal bone loss. The ovariectomized rat, a widely used preclinical model for studying postmenopausal bone loss that mimics deterioration of bone tissue in the hip and spine, can also be used to study mineral and structural changes in alveolar bone to develop drug and/or dietary strategies aimed at tooth retention. This review discusses key findings from studies investigating mandible health and alveolar bone in the ovariectomized rat model. Considerations to maximize the benefits of this model are also included. These include the measurement techniques used, the age at ovariectomy, the duration that a rat is studied after ovariectomy and habitual diet consumed.

  19. The Ovariectomized Rat as a Model for Studying Alveolar Bone Loss in Postmenopausal Women

    Science.gov (United States)

    Johnston, Bryan D.; Ward, Wendy E.

    2015-01-01

    In postmenopausal women, reduced bone mineral density at the hip and spine is associated with an increased risk of tooth loss, possibly due to a loss of alveolar bone. In turn, having fewer natural teeth may lead to compromised food choices resulting in a poor diet that can contribute to chronic disease risk. The tight link between alveolar bone preservation, tooth retention, better nutritional status, and reduced risk of developing a chronic disease begins with the mitigation of postmenopausal bone loss. The ovariectomized rat, a widely used preclinical model for studying postmenopausal bone loss that mimics deterioration of bone tissue in the hip and spine, can also be used to study mineral and structural changes in alveolar bone to develop drug and/or dietary strategies aimed at tooth retention. This review discusses key findings from studies investigating mandible health and alveolar bone in the ovariectomized rat model. Considerations to maximize the benefits of this model are also included. These include the measurement techniques used, the age at ovariectomy, the duration that a rat is studied after ovariectomy and habitual diet consumed. PMID:26060817

  20. Mid-ocean ridges, InRidge and the future

    Digital Repository Service at National Institute of Oceanography (India)

    Iyer, S.D.; Mukhopadhyay, R.; Drolia, R.K.; Ray, Dwijesh

    , Canada, France, Germany, Iceland, Italy, Japan, Korea, Mexico, Norway, Portugal, Russia, Spain, UK and US pooled in their expertise. Some of the national ridge research programmes of various coun - tries ar e: Bridge (Britain, this programme is now...) to oversee the development and implementation of its various programmes. This committee consists of a cross - section of the global ridge researchers. A central office (presently in Japan) is invol - ved to plan activities, hold special conferences...

  1. Bone Replacement Materials and Techniques Used for Achieving Vertical Alveolar Bone Augmentation

    Directory of Open Access Journals (Sweden)

    Zeeshan Sheikh

    2015-05-01

    Full Text Available Alveolar bone augmentation in vertical dimension remains the holy grail of periodontal tissue engineering. Successful dental implant placement for restoration of edentulous sites depends on the quality and quantity of alveolar bone available in all spatial dimensions. There are several surgical techniques used alone or in combination with natural or synthetic graft materials to achieve vertical alveolar bone augmentation. While continuously improving surgical techniques combined with the use of auto- or allografts provide the most predictable clinical outcomes, their success often depends on the status of recipient tissues. The morbidity associated with donor sites for auto-grafts makes these techniques less appealing to both patients and clinicians. New developments in material sciences offer a range of synthetic replacements for natural grafts to address the shortcoming of a second surgical site and relatively high resorption rates. This narrative review focuses on existing techniques, natural tissues and synthetic biomaterials commonly used to achieve vertical bone height gain in order to successfully restore edentulous ridges with implant-supported prostheses.

  2. Biodegradable effect of PLGA membrane in alveolar bone regeneration on beagle dog.

    Science.gov (United States)

    Hua, Nan; Ti, Vivian Lao; Xu, Yuanzhi

    2014-11-01

    Guided bone regeneration (GBR) is a principle adopted from guided tissue regeneration (GTR). Wherein, GBR is used for the healing of peri-implant bony dehiscences, for the immediate placement of implants into extraction sockets and for the augmentation of atrophic alveolar ridges. This procedure is done by the placement of a resorbable or non-resorbable membrane that will exclude undesirable types of tissue growth between the extraction socket and the soft tissue to allow only bone cells to regenerate in the surgically treated lesion. Here, we investigated the biodegradable effect of polylactic-co-glycolic acid (PLGA) membrane in the alveolar bone on Beagle dogs. Results show that both collagen and PLGA membrane had been fully resorbed, biodegraded, at four weeks post-operative reentry into the alveolar bone. Histological results under light microscopy revealed formation of new bone trabeculae in the extraction sites on both collagen and PLGA membrane. In conclusion, PLGA membrane could be a potential biomaterials for use on GBR and GTR. Nevertheless, further studies will be necessary to elucidate the efficiency and cost effectiveness of PLGA as GBR membrane in clinical.

  3. Quantitative electron microscopic analysis of the epithelium of normal human alveolar mucosa.

    Science.gov (United States)

    Bernimoulin, J P; Schroeder, H E

    1977-05-31

    The epithelium of normal human alveolar mucosa originating from the anterior vestibulum was subjected to stereologic analysis. Eight biopsies were collected half-way between the muco gingival junction and the vestibular fornix from 20 to 50 year-old females, and processed for light and electron microscopy. At two levels of magnification, electron micrographs were sampled from four artificially selected strata in regions of epithelial ridges. Stereologic point counting based on a computer-aided system for analyzing stratified epithelia served for examining a total of about 860 electron micrographs. The alveolar epithelium was 0.26 mm thick, occasionally interdigitated by short, slender connective tissue papillae, and consisted of (1) a narrow basal and suprabasal, and (2) a broad spinous and surface compartment. It displayed a differentiation pattern which, in most subjects studied, was similar to that of normal human buccal epithelium, however, on the average, produced less mature surface cells. This pattern was expressed mainly by a density increase of cytoplasmic filaments (98 A in diameter), a concomitant decrease of the cytoplasmic ground substance, the formation of dark-cored membrane coating granules, and invividually variable amounts of glycogen deposition. In some subjects, a mixed differentiation pattern was found. The structural organization of alveolar epithelium, in analogy to cheek epithelium, was compatible with the function of distensibility.

  4. A method for measuring post-extraction alveolar dimensional changes with volumetric computed tomography.

    Science.gov (United States)

    Bontá, Hernán; Galli, Federico G; Caride, Facundo; Carranza, Nelson

    2012-01-01

    The aim of this study is to present a predictable method for evaluating dimensional changes in the alveolar ridge through cone beam computed tomography (CT). Twenty subjects with single-rooted tooth extraction indication were selected for this preliminary report, which is part of a larger ongoing investigation. After extraction, two CT scans were performed; the first within 24 hours post-extraction (TC1) and the second 6 months (TC2) later. A radiographic guide with a radiopaque element placed along the tooth axis was developed to locate the same plane of reference in two different CT scans. For each patient, backtrack analysis was performed in order to establish the reproducibility error of a predetermined point in space between two CT scans. Briefly, an anatomical landmark was selected and its coordinates to the radiopaque marker were recorded. One week later, the coordinates were followed backwards in the same CT scan to obtain the position where the reference point should be located. A similar process was carried out between two different CT scans taken 6 months apart. The distance between the anatomical reference and the obtained point of position was calculated to establish the accuracy of the method. Additionally, a novel method for evaluating dimensional changes of the alveolus after tooth extraction is presented. The backtrack analysis determined an average within-examiner discrepancy between both measurements from the same CT scan of 0.19 mm. SD +/- 0.05. With the method presented herein, a reference point in a CT scan can be accurately backtracked and located in a second CT scan taken six months later. Taken together they open the possibility of calculating dimensional changes that occur in the alveolar ridge over time, such as post-extraction alveolar resorption, or the bone volume gained after different augmentation procedures.

  5. Evaluation of the posterior superior alveolar artery and the maxillary sinus with CBCT

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    Dilhan Ilguy

    2013-09-01

    Full Text Available Assessment of the maxillary sinus anatomy before sinus augmentation is important for avoiding surgical complications, because of the close anatomical relationship between the posterior maxillary teeth and the maxillary sinus. The posterior superior alveolar artery (PSAA is the branch of the maxillary artery that supplies the lateral sinus wall and overlying membrane. We evaluated the location of the PSAA and its relationship to the alveolar ridge and maxillary sinus using cone beam computed tomography (CBCT. The study group consisted of 135 CBCT scans (270 sinuses obtained from the archive of the dentomaxillofacial radiology department at Yeditepe University Faculty of Dentistry, Istanbul, Turkey. The distance between the lower border of the artery and the alveolar crest, bone height from the sinus floor to the ridge crest, distance from the artery to the medial sinus wall, and the diameter and location of the artery were determined. The occurrence of septa and pathology were recorded from CBCT scans. The PSAA was observed in 89.3% of sinuses, and 71.1% of arteries were intraosseous with diameters mostly < 1 mm (68.9%. The prevalence of sinus septa was 55.2%, and that of sinus pathology was 57.4%. The mean age was 43.07 ± 17.55 years. There was a statistically significant difference between the location of the artery and gender (p < 0.05. The prevalence of sinus membrane thickening was 57.4%. Detailed knowledge about the location of the PSAA and sinus morphology may be obtained with CBCT before maxillary sinus surgery.

  6. Alveolar distraction osteogenesis – Crestal widening by distraction osteogenesis

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    Zvi Laster

    2010-04-01

    Full Text Available Following tooth extraction, resorption of the residual ridges occurs in both the vertical and the horizontal directions. Most of this resorption occurs within the first 6 months after tooth extraction. To correc tthis vertical/ horizontal/ dual situation, several surgical approaches have been proposed: autogenous bone grafts, guided bone regeneration, and alveolar distraction osteogenesis (ADO. In recent years, ADO has gained an ongoing popularity ,especially in view of its numerous advantages, mostimportant among them being the shortening of treatment periods and earlier dental implant placement. In cases in which there is sufficient vertical height but not enough bucco-ligual width to accommodate an implant, crestal width has to be built. Crestal widening by distraction osteogenesis is the preferred technique in suchcases. In this study a new type of crest widener, the"Laster" Crest Widening Distractor, is presented, reporting two cases where crest widening by distraction was chosen as the preferred treatment plan. Finally the main advantages and disadvantages of the new crest widening distractor are discussed, helping thus the clinician to make up his mind about this new promising device and surgical technique.

  7. Growth of a tectonic ridge

    Energy Technology Data Exchange (ETDEWEB)

    Fleming, R.W.; Messerich, J.A. [Geological Survey, Denver, CO (United States); Johnson, A.M. [Purdue Univ., West Lafayette, IN (United States). Dept. of Earth and Atmospheric Sciences

    1997-12-31

    The 28 June 1992 Landers, California, earthquake of M 7.6 created an impressive record of surface rupture and ground deformation. Fractures extend over a length of more than 80 km including zones of right-lateral shift, steps in the fault zones, fault intersections and vertical changes. Among the vertical changes was the growth of a tectonic ridge described here. In this paper the authors describe the Emerson fault zone and the Tortoise Hill ridge including the relations between the fault zone and the ridge. They present data on the horizontal deformation at several scales associated with activity within the ridge and belt of shear zones and show the differential vertical uplifts. And, they conclude with a discussion of potential models for the observed deformation.

  8. Repeat ridge jumps associated with plume-ridge interaction, melt transport, and ridge migration

    Science.gov (United States)

    Mittelstaedt, Eric; Ito, Garrett; van Hunen, Jeroen

    2011-01-01

    Repeated shifts, or jumps, of mid-ocean ridge segments toward nearby hot spots can produce large, long-term changes to the geometry and location of the tectonic plate boundaries. Ridge jumps associated with hot spot-ridge interaction are likely caused by several processes including shear on the base of the plate due to expanding plume material as well as reheating of lithosphere as magma passes through it to feed off-axis volcanism. To study how these processes influence ridge jumps, we use numerical models to simulate 2-D (in cross section) viscous flow of the mantle, viscoplastic deformation of the lithosphere, and melt migration upward from the asthenospheric melting zone, laterally along the base of the lithosphere, and vertically through the lithosphere. The locations and rates that magma penetrates and heats the lithosphere are controlled by the time-varying accumulation of melt beneath the plate and the depth-averaged lithospheric porosity. We examine the effect of four key parameters: magmatic heating rate of the lithosphere, plate spreading rate, age of the seafloor overlying the plume, and the plume-ridge migration rate. Results indicate that the minimum value of the magmatic heating rate needed to initiate a ridge jump increases with plate age and spreading rate. The time required to complete a ridge jump decreases with larger values of magmatic heating rate, younger plate age, and faster spreading rate. For cases with migrating ridges, models predict a range of behaviors including repeating ridge jumps, much like those exhibited on Earth. Repeating ridge jumps occur at moderate magmatic heating rates and are the result of changes in the hot spot magma flux in response to magma migration along the base of an evolving lithosphere. The tendency of slow spreading to promote ridge jumps could help explain the observed clustering of hot spots near the Mid-Atlantic Ridge. Model results also suggest that magmatic heating may significantly thin the lithosphere

  9. Alveolar rhabdomyosarcoma in children with histomorphological review

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    S. K. Nema

    2014-04-01

    Full Text Available Rhabdomyosarcomas (RMS are aggressive malignant neoplasm of mesenchymal origin, related to skeletal muscle lineage. These are the most common soft tissue tumors in children. The diagnosis is made by microscopic analysis and ancillary techniques like immunohistochemistry, electron microscopy, cytogenetics and molecular biology. We encountered a case of a 03 years old child who presented with a tender, reddish, soft swelling over cheek for three weeks. The FNAC was reported as a small round cell tumor, Probably Primitive Neuroectodermal Tumor (PNET. The biopsy of tumor revealed a small round cell tumor with an alveolar pattern. Tumor giant cells were absent and mitotic figures were infrequent. Hence, differentials of alveolar rhabdomyosarcoma and PNET were rendered. Immunohistochemistry (IHC demonstrated desmin positivity. Thus, a final diagnosis of alveolar rhabdomyosarcoma was offered. [Int J Res Med Sci 2014; 2(2.000: 775-778

  10. Lateralization Technique and Inferior Alveolar Nerve Transposition

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    Angélica Castro Pimentel

    2016-01-01

    Full Text Available Bone resorption of the posterior mandible can result in diminished bone edge and, therefore, the installation of implants in these regions becomes a challenge, especially in the presence of the mandibular canal and its contents, the inferior alveolar nerve. Several treatment alternatives are suggested: the use of short implants, guided bone regeneration, appositional bone grafting, distraction osteogenesis, inclined implants tangential to the mandibular canal, and the lateralization of the inferior alveolar nerve. The aim was to elucidate the success rate of implants in the lateralization technique and in inferior alveolar nerve transposition and to determine the most effective sensory test. We conclude that the success rate is linked to the possibility of installing implants with long bicortical anchor which favors primary stability and biomechanics.

  11. Lateralization Technique and Inferior Alveolar Nerve Transposition

    Science.gov (United States)

    Sanches, Marco Antonio; Ramalho, Gabriel Cardoso; Manzi, Marcello Roberto

    2016-01-01

    Bone resorption of the posterior mandible can result in diminished bone edge and, therefore, the installation of implants in these regions becomes a challenge, especially in the presence of the mandibular canal and its contents, the inferior alveolar nerve. Several treatment alternatives are suggested: the use of short implants, guided bone regeneration, appositional bone grafting, distraction osteogenesis, inclined implants tangential to the mandibular canal, and the lateralization of the inferior alveolar nerve. The aim was to elucidate the success rate of implants in the lateralization technique and in inferior alveolar nerve transposition and to determine the most effective sensory test. We conclude that the success rate is linked to the possibility of installing implants with long bicortical anchor which favors primary stability and biomechanics. PMID:27433360

  12. The timescales of magma evolution at mid-ocean ridges

    Science.gov (United States)

    Brandl, Philipp A.; Regelous, Marcel; Beier, Christoph; O'Neill, Hugh St. C.; Nebel, Oliver; Haase, Karsten M.

    2016-01-01

    Oceanic crust is continuously created at mid-ocean ridges by decompression melting of the upper mantle as it upwells due to plate separation. Decades of research on active spreading ridges have led to a growing understanding of the complex magmatic, tectonic and hydrothermal processes linked to the formation of new oceanic igneous crust. However, less is known about the timescales of magmatic processes at mid-ocean ridges, including melting in and melt extraction from the mantle, fractional crystallisation, crustal assimilation and/or magma mixing. In this paper, we review the timescales of magmatic processes by integrating radiometric dating, chemical and petrological observations of mid-ocean ridge basalts (MORBs) and geophysical models. These different lines of evidence suggest that melt extraction and migration, and crystallisation and mixing processes occur over timescales of 1 to 10,000 a. High-resolution geochemical stratigraphic profiles of the oceanic crust using drill-core samples further show that at fast-spreading ridges, adjacent flow units may differ in age by only a few 100 a. We use existing chemical data and new major- and trace-element analyses of fresh MORB glasses from drill-cores in ancient Atlantic and Pacific crust, together with model stratigraphic ages to investigate how lava chemistry changes over 10 to 100 ka periods, the timescale of crustal accretion at spreading ridges which is recorded in the basalt stratigraphy in drilled sections through the oceanic crust. We show that drilled MORBs have compositions that are similar to those of young MORB glasses dredged from active spreading ridges (lavas that will eventually be preserved in the lowermost part of the extrusive section covered by younger flows), showing that the dredged samples are indeed representative of the bulk oceanic crust. Model stratigraphic ages calculated for individual flows in boreholes, together with the geochemical stratigraphy of the drilled sections, show that at

  13. Basaloid Squamous Cell Carcinoma Involving the Alveolar Ridge, Buccal & Lingual Vestibule - A Case Report

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    Supriya Koshti

    2013-01-01

    Full Text Available Background: Basaloid squamous cell carcinoma of oral mucosa is a rare and aggressive variant of squamous cell carcinoma. They can be differentiated from squamous cell carcinomas by their distinct clinical and histopathological features. Methods: 45 year old female patient presented with extra oral exophytic mass and intra-oral ulcerative lesion on right buccal mucosa and vestibule. The patient was referred for routine blood examination and radiography followed by incisional biopsy. The biopsy specimen was fixed, processed and stained with Hematoxylin and Eosin for further microscopic examination. Results: On microscopic examination basaloid cells were seen proliferating along with dysplastic squamous cells in the connective tissue stroma. Conclusion: Based on the histopathological findings a diagnosis of ′Basaloid squamous cell carcinoma′ was made. The patient was referred to department of Oral and Maxillofacial Surgery for excision of the lesion followed by radiotherapy.

  14. Bone grafting of alveolar socket and ovate seat pontic preparation for natural emergence profile for anterior bridge - A case report

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    Vijay Deshmukh

    2009-01-01

    Full Text Available Alveolar atrophy following tooth extraction remains a challenge for future prosthetic restorations. Immediate implant placement and postextraction alveolar bone grafting are two methods that are used to prevent significant postextraction bone loss. Grafting is one of the most common methods of socket preservation widely used to prevent the collapse of oral tissues following extraction so that an excellent esthetic prosthesis can be provided particularly in the anterior maxillary region. The present report describes the management of a maxillary tooth extraction socket using a socket preservation technique involving placement of an osteoconductive slowly resorbable grafting material & resorbable collagen membrane in the extraction socket also called as Bio-Col socket preservation technique followed by a provisional restoration to preserve the tissues & interdental papilla for the placement of future final ovate pontic anterior bridge to give the illusion of the tooth emerging from the gums. This technique resulted in a successful prevention of alveolar bone loss following tooth extraction & maintainence of tissue contour & density which provided a good tissue base for the fabrication of Ovate pontic giving excellent esthetic results.

  15. Exogenous hydrogen sulfide (H2S protects alveolar growth in experimental O2-induced neonatal lung injury.

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    Arul Vadivel

    Full Text Available BACKGROUND: Bronchopulmonary dysplasia (BPD, the chronic lung disease of prematurity, remains a major health problem. BPD is characterized by impaired alveolar development and complicated by pulmonary hypertension (PHT. Currently there is no specific treatment for BPD. Hydrogen sulfide (H2S, carbon monoxide and nitric oxide (NO, belong to a class of endogenously synthesized gaseous molecules referred to as gasotransmitters. While inhaled NO is already used for the treatment of neonatal PHT and currently tested for the prevention of BPD, H2S has until recently been regarded exclusively as a toxic gas. Recent evidence suggests that endogenous H2S exerts beneficial biological effects, including cytoprotection and vasodilatation. We hypothesized that H2S preserves normal alveolar development and prevents PHT in experimental BPD. METHODS: We took advantage of a recently described slow-releasing H2S donor, GYY4137 (morpholin-4-ium-4-methoxyphenyl(morpholino phosphinodithioate to study its lung protective potential in vitro and in vivo. RESULTS: In vitro, GYY4137 promoted capillary-like network formation, viability and reduced reactive oxygen species in hyperoxia-exposed human pulmonary artery endothelial cells. GYY4137 also protected mitochondrial function in alveolar epithelial cells. In vivo, GYY4137 preserved and restored normal alveolar growth in rat pups exposed from birth for 2 weeks to hyperoxia. GYY4137 also attenuated PHT as determined by improved pulmonary arterial acceleration time on echo-Doppler, pulmonary artery remodeling and right ventricular hypertrophy. GYY4137 also prevented pulmonary artery smooth muscle cell proliferation. CONCLUSIONS: H2S protects from impaired alveolar growth and PHT in experimental O2-induced lung injury. H2S warrants further investigation as a new therapeutic target for alveolar damage and PHT.

  16. Three-dimensional evaluation of upper anterior alveolar bone dehiscence after incisor retraction and intrusion in adult patients with bimaxillary protrusion malocclusion*

    Science.gov (United States)

    Guo, Qing-yuan; Zhang, Shi-jie; Liu, Hong; Wang, Chun-ling; Wei, Fu-lan; Lv, Tao; Wang, Na-na; Liu, Dong-xu

    2011-01-01

    Objective: The purpose of this study was to evaluate three-dimensional (3D) dehiscence of upper anterior alveolar bone during incisor retraction and intrusion in adult patients with maximum anchorage. Methods: Twenty adult patients with bimaxillary dentoalveolar protrusion had the four first premolars extracted. Miniscrews were placed to provide maximum anchorage for upper incisor retraction and intrusion. A computed tomography (CT) scan was performed after placement of the miniscrews and treatment. The 3D reconstructions of pre- and post-CT data were used to assess the dehiscence of upper anterior alveolar bone. Results: The amounts of upper incisor retraction at the edge and apex were (7.64±1.68) and (3.91±2.10) mm, respectively, and (1.34±0.74) mm of upper central incisor intrusion. Upper alveolar bone height losses at labial alveolar ridge crest (LAC) and palatal alveolar ridge crest (PAC) were 0.543 and 2.612 mm, respectively, and the percentages were (6.49±3.54)% and (27.42±9.77)%, respectively. The shape deformations of LAC-labial cortex bending point (LBP) and PAC-palatal cortex bending point (PBP) were (15.37±5.20)° and (6.43±3.27)°, respectively. Conclusions: Thus, for adult patients with bimaxillary protrusion, mechanobiological response of anterior alveolus should be taken into account during incisor retraction and intrusion. Pursuit of maximum anchorage might lead to upper anterior alveolar bone loss. PMID:22135148

  17. Three-dimensional evaluation of upper anterior alveolar bone dehiscence after incisor retraction and intrusion in adult patients with bimaxillary protrusion malocclusion

    Institute of Scientific and Technical Information of China (English)

    Qing-yuan GUO; Shi-jie ZHANG; Hong LIU; Chun-ling WANG; Fu-lan WEI; Tao LV; Na-na WANG; Dong-xu LIU

    2011-01-01

    Objective: The purpose of this study was to evaluate three-dimensional (3D) dehiscence of upper anterior alveolar bone during incisor retraction and intrusion in adult patients with maximum anchorage.Methods: Twenty adult patients with bimaxillary dentoalveolar protrusion had the four first premolars extracted.Miniscrews were placed to provide maximum anchorage for upper incisor retraction and intrusion.A computed tomography (CT) scan was performed after placement of the miniscrews and treatment.The 3D reconstructions of pre- and post-CT data were used to assess the dehiscence of upper anterior alveolar bone.Results: The amounts of upper incisor retraction at the edge and apex were (7.64±1.68) and (3.91±2.10) mm,respectively,and (1.34±0.74) mm of upper central incisor intrusion.Upper alveolar bone height losses at labial alveolar ridge crest (LAC) and palatal alveolar ridge crest (PAC) were 0.543 and 2.612 mm,respectively,and the percentages were (6.49±3.54)% and (27.42±9.77)%,respectively.The shape deformations of LAC-labial cortex bending point (LBP) and PAC-palatal cortex bending point (PBP) were (15.37±5.20)° and (6.43±3.27)°,respectively.Conclusions: Thus,for adult patients with bimaxillary protrusion,mechanobiological response of anterior alveolus should be taken into account during incisor retraction and intrusion.Pursuit of maximum anchorage might lead to upper anterior alveolar bone loss.

  18. Orthodontically guided bone transport in the treatment of alveolar cleft: A case report

    Science.gov (United States)

    Gómez, Elena; Otero, Marta; Berraquero, Rosario; Wucherpfennig, Begona; Hernández-Godoy, Juan; Guiñales, Jorge; Vincent, Germán; Burgueño, Miguel

    2016-01-01

    Introduction Conventional treatments are sometimes not possible in certain alveolar cleft cases due to the severity of the gap which separates the fragments. Various management strategies have been proposed, including sequential surgical interventions or delaying treatment until adulthood to then carry out maxillary osteotomies. A further alternative approach has also been proposed, involving the application of bone transport techniques to mobilise the osseous fragments and thereby reduce the gap between lateral fragments and the premaxilla. Case Report We introduce the case of a 10-year-old patient who presented with a bilateral alveolar cleft and a severe gap. Stable occlusion between the premaxilla and the mandible was achieved following orthodontic treatment, making it inadvisable to perform a retrusive osteotomy of the premaxilla in order to close the alveolar clefts. Faced with this situation, it was decided we would employ a bone transport technique under orthodontic guidance using a dental splint. This would enable an osseous disc to be displaced towards the medial area and reduce the interfragmentary distance. During a second surgical intervention, closure of the soft tissues was performed and the gap was filled in using autogenous bone. Conclusions The use of bone transport techniques in selected cases allows closure of the osseous defect, whilst also preserving soft tissues and reducing the amount of bone autograft required. In our case, we were able to respect the position of the premaxilla and, at the same time, generate new tissues at both an alveolar bone and soft tissue level with results which have remained stable over the course of time. Key words:Alveolar cleft, bone transport, graft. PMID:26855699

  19. Carpenter Ridge Tuff, CO

    Science.gov (United States)

    Bachmann, Olivier; Deering, Chad D.; Lipman, Peter W.; Plummer, Charles

    2014-06-01

    The ~1,000 km3 Carpenter Ridge Tuff (CRT), erupted at 27.55 Ma during the mid-tertiary ignimbrite flare-up in the western USA, is among the largest known strongly zoned ash-flow tuffs. It consists primarily of densely welded crystal-poor rhyolite with a pronounced, highly evolved chemical signature (high Rb/Sr, low Ba, Zr, Eu), but thickly ponded intracaldera CRT is capped by a more crystal-rich, less silicic facies. In the outflow ignimbrite, this upper zone is defined mainly by densely welded crystal-rich juvenile clasts of trachydacite composition, with higher Fe-Ti oxide temperatures, and is characterized by extremely high Ba (to 7,500 ppm), Zr, Sr, and positive Eu anomalies. Rare mafic clasts (51-53 wt% SiO2) with Ba contents to 4,000-5,000 ppm and positive Eu anomalies are also present. Much of the major and trace-element variations in the CRT juvenile clasts can be reproduced via in situ differentiation by interstitial melt extraction from a crystal-rich, upper-crustal mush zone, with the trachydacite, crystal-rich clasts representing the remobilized crystal cumulate left behind by the melt extraction process. Late recharge events, represented by the rare mafic clasts and high-Al amphiboles in some samples, mixed in with parts of the crystal cumulate and generated additional scatter in the whole-rock data. Recharge was important in thermally remobilizing the silicic crystal cumulate by partially melting the near-solidus phases, as supported by: (1) ubiquitous wormy/sieve textures and reverse zoning patterns in feldspars and biotites, (2) absence of quartz in this very silicic unit stored at depths of >4-5 km, and (3) heterogeneous melt compositions in the trachydacite fiamme and mafic clasts, particularly in Ba, indicating local enrichment of this element due mostly to sanidine and biotite melting. The injection of hot, juvenile magma into the upper-crustal cumulate also imparted the observed thermal gradient to the deposits and the mixing overprint that

  20. The Minimum Alveolar Concentration of Sevoflurane for Respiratory Depression

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    V. V. Likhvantsev

    2011-01-01

    Full Text Available Objective: to provide a rationale for a need to introduce the new constant — the minimum alveolar concentration for respiratory depression (MACrespiratory depression and to determine its value. Subjects and methods. Forty-three patients aged 20— 45 years, who had normal weight and ASA physical status I—II, were examined. All the patients underwent induction of sevorane anesthesia without narcotic analgesics, nitrous oxide, and myorelaxants. A laryngeal mask was installed after MAClm was achieved. Sevorane concentrations were increased on a vaporizer, by changing Etanesth at a rate of 0.2 vol% per min until Etanesthresp;ratory depression was achieved. Results. A rationale was provided for a need to introduce the new inhalation anesthesia constant MACrespiratory depression that is, in accordance with the MAC conception, regarded as the inhalation anesthetic concentration that necessitates assisted ventilation in 50% of the patients. MACrespiratory depression was 1.8 MAC. This is essentially more than both MAC and 1.3 MAC, the anesthetic concentration at which any operation can be performed in 90% of patients. At the same time, the derived value of 3.7 vol% is somewhat below MACbarr (4.07 vol%, which means that anesthesia with sevorane only under spontaneous respiration will be inadequate in few patients or its performance will be associated with the risk of hypoxia. Conclusion. The authors’ successively developed concept of anesthesia with preserved spontaneous respiration necessitates the introduction of the new inhalation anesthesia constant MACrespiratory depression. Its value is 3.7% vol% for sevoflurane. Key words: induction of anesthesia, minimum alveolar concentration, spontaneous respiration, inhalation anesthesia.

  1. Alveolar proteinosis associated with aluminium dust inhalation.

    Science.gov (United States)

    Chew, R; Nigam, S; Sivakumaran, P

    2016-08-01

    Secondary alveolar proteinosis is a rare lung disease which may be triggered by a variety of inhaled particles. The diagnosis is made by detection of anti-granulocyte-macrophage colony-stimulating factor antibodies in bronchoalveolar lavage fluid, which appears milky white and contains lamellar bodies. Aluminium has been suggested as a possible cause, but there is little evidence in the literature to support this assertion. We report the case of a 46-year-old former boilermaker and boat builder who developed secondary alveolar proteinosis following sustained heavy aluminium exposure. The presence of aluminium was confirmed both by histological examination and metallurgical analysis of a mediastinal lymph node. Despite cessation of exposure to aluminium and treatment with whole-lung lavage which normally results in improvements in both symptoms and lung function, the outcome was poor and novel therapies are now being used for this patient. It may be that the natural history in aluminium-related alveolar proteinosis is different, with the metal playing a mediating role in the disease process. Our case further supports the link between aluminium and secondary alveolar proteinosis and highlights the need for measures to prevent excessive aluminium inhalation in relevant industries. © The Author 2016. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Iatrogenic injury to the inferior alveolar nerve

    DEFF Research Database (Denmark)

    Hillerup, Søren

    2008-01-01

    The purpose of this prospective, non-randomised, descriptive study is to characterise the neurosensory deficit and associated neurogenic discomfort in 52 patients with iatrogenic injury to the inferior alveolar nerve (IAN). All patients were examined and followed up according to a protocol assess...

  3. Staged ridge-split evaluated using cone beam computed tomography and peri-implant plastic surgery in the mandibular arch

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    Nikhil Vasant Jain

    2015-01-01

    Full Text Available Lack of sufficient bone to place an implant at a functionally and an esthetically appropriate position is a common problem, especially in the mandibular posterior region. Narrow edentulous alveolar ridges <5 mm wide require bone augmentation before implant placement to establish a bony wall of at least 1 mm around the endosseous implant. Various surgical widening techniques are available, including lateral augmentation with or without guided bone regeneration, ridge-split technique and horizontal distraction osteogenesis. The ridge-split technique aims at creating a new implant bed by longitudinal osteotomy of the alveolar bone. The buccal cortex is repositioned laterally by greenstick fracture, and the space between the buccal and lingual cortices is filled with a graft material. Peri-implant plastic surgery focuses on harmonizing peri-implant structures by means of hard- and soft-tissue engineering and includes bone structure enhancement, soft-tissue enhancement, precision in implant placement and improves quality of the prosthetic restoration. The rationale for the peri-implant plastic surgery approach goes well beyond pure esthetics as it creates peri-implant keratinized mucosa and interimplant soft-tissue height in order to avoid food impaction, interimplant airflow, and speech problems. This case report demonstrates a staged ridge-split technique evaluated with cone beam computed tomography using a piezosurgical unit and a surgical technique to restore a papilla-like tissue at the time of the second-stage implant surgery.

  4. Residual ridge dimensions at edentulous maxillary first molar sites and periodontal bone loss among two ethnic cohorts seeking tooth replacement.

    Science.gov (United States)

    Acharya, Aneesha; Hao, Jia; Mattheos, Nikos; Chau, Anson; Shirke, Prashant; Lang, Niklaus P

    2014-12-01

    To study residual ridge dimensions at edentulous first molar sites in relation to periodontal bone loss among cohorts of partially edentulous Asian Indian and Hong Kong Chinese subjects seeking tooth replacement. A total of 628 edentulous maxillary first molar sites were analyzed on Cone Beam Computed Tomography scans of 225 Asian Indian (I) and 232 Hong Kong Chinese (C) partially edentulous adults seeking tooth replacement. Age, ethnicity, gender, total tooth loss, the presence or absence of adjacent teeth, categories of periodontal status defined according to radiographic alveolar bone loss (P0: periodontal health, P1: incipient to moderate disease, P2: severe periodontal disease) and sinus membrane abnormalities were noted. Alveolar ridge height (RH), widths at 1 and 3 mm from crest (RW1; RW3), and relative position of the bone crest (RR) were measured. Prevalence of P2 status was most frequent in both cohorts(C: 50.4% I: 49.2%). P2 had lowest ridge heights; 13.1% C P2 and 14%I P2 had RH Sinus membrane abnormalities were most frequent in P2. Periodontal status and sinus membrane abnormality increased the odds of RH sinus membrane thickening affected available bone height in the subsinus region, while the presence of adjacent teeth- and age-affected residual ridge width. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. [Preliminary application of injectable calcium phosphate cement/poly (lactic-co-glycolic acid) microspheres for extraction site preservation].

    Science.gov (United States)

    Mai, Yuying; Wu, Huihuang; Mai, Zhisong; Li, Xinghong; Huang, Linhui; Liao, Hongbing

    2014-03-01

    To investigate the feasibility of extraction site preservation using injectable calcium phosphate cement (CPC) combine with poly (lactic-co-glycolic acid) (PLGA) microspheres. Immediate extraction defects models were created in canine mandibles, and the defects were filled with CPC/PLGA (experimental group, E) , Bio-Oss (positive control, P), non-treatment (blank control, B) respectively. Dogs were sacrificed after 4, 8, 12 weeks post operation. Statistical analysis were conducted using SPSS 19. of radiological observation showed that there were not significantly different between groups in 4 and 8 week (P > 0.05). After 12 week,E (114.9 ± 8.4) were not significantly different compared with P (117.4 ± 12.1) (P > 0.05) , both were significantly higher than B (95.0 ± 12.6) (P B[(78.7 ± 2.7)%] > E[(69.2 ± 1.8)%] (P < 0.05). At 8, 12 week, results of P[(94.0 ± 2.3)% and (93.5 ± 1.9) %] and E[ (94.7 ± 1.1) % and (96.0 ± 0.9) %] were better than those of B[ (76.8 ± 3.0)% and (87.0 ± 2.4)%] (P < 0.05). The effect of CPC/PLGA repair immediate alveolar ridge defects is the same as that of Bio-Oss, and CPC/PLGA can be used as a material in extraction site preservation.

  6. Spin-orbit interaction and asymmetry effects on Kondo ridges at finite magnetic field

    DEFF Research Database (Denmark)

    Grap, Stephan; Andergassen, Sabine; Paaske, Jens

    2011-01-01

    ridges, which are robust against SOI as time-reversal symmetry is preserved. As a result of the crossing of a spin-up and a spin-down level at vanishing SOI, two additional Kondo plateaus appear at finite B. They are not protected by symmetry and rapidly vanish if the SOI is turned on. Left...

  7. Catfish Preservation using Porphyra Yezoensis Composites Preservatives

    Directory of Open Access Journals (Sweden)

    Zhi-Gang Qian

    2013-09-01

    Full Text Available This study aims to preserve fresh catfish meat by using Porphyra Yezoensis extract, chitosan and lactic acid Nisin. The composite preservative obtained by sensory evaluation can effectively maintain the color, odor and texture of fresh catfish meat, as well as inhibit bacterial growth. Results show that treatment using a preservative solution (Porphyra Yezoensis extract 10%, Nisin 0.2% and chitosan 15% extended the shelf life of the fresh catfish meat from 12 h to 24 h when stored at room temperature and from 6 d to 9 d when stored at 4°C. These results provide a practical method of preserving fresh catfish meat.

  8. Architectural/historical assessment of the Oak Ridge National Laboratory, Oak Ridge Reservation, Anderson and Roane Counties, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Carver, M.; Slater, M.

    The Department of Energy (DOE) is required by the National Historic Preservation Act (NHPA) of 1966, as amended, to identify any properties under its jurisdiction that are included in or eligible for inclusion in the National Register of Historic Places (National Register). In March 1993 Duvall & Associates, Inc., was engaged to survey the Oak Ridge National Laboratory (ORNL), a DOE facility located on the Oak Ridge Reservation (ORR) in Anderson and Roane Counties, Tennessee, and to prepare a determination of National Register eligibility for all ORNL properties. The purpose of this report is to summarize the results of research into the historical context of ORNL and at to identify historic properties at ORNL that are included in present or eligible for inclusion in the National Register. The identification of archaeological properties at ORNL that are included and eligible for inclusion in the National Register Clinton is addressed in a separate report.

  9. Oak Ridge callibration recall program

    Energy Technology Data Exchange (ETDEWEB)

    Falter, K.G.; Wright, W.E. [Oak Ridge National Lab., TN (United States); Pritchard, E.W. [Oak Ridge Centers for Manufacturing Technology, TN (United States)] [and others

    1996-12-31

    A development effort was initiated within the Oak Ridge metrology community to address the need for a more versatile and user friendly tracking database that could be used across the Oak Ridge complex. This database, which became known as the Oak Ridge Calibration Recall Program (ORCRP), needed to be diverse enough for use by all three Oak Ridge facilities, as well as the seven calibration organizations that support them. Various practical functions drove the initial design of the program: (1) accessible by any user at any site through a multi-user interface, (2) real-time database that was able to automatically generate e-mail notices of due and overdue measuring and test equipment, (3) large memory storage capacity, and (4) extremely fast data access times. In addition, the program needed to generate reports on items such as instrument turnaround time, workload projections, and laboratory efficiency. Finally, the program should allow the calibration intervals to be modified, based on historical data. The developed program meets all of the stated requirements and is accessible over a network of computers running Microsoft Windows software.

  10. Ridge Regression for Interactive Models.

    Science.gov (United States)

    Tate, Richard L.

    1988-01-01

    An exploratory study of the value of ridge regression for interactive models is reported. Assuming that the linear terms in a simple interactive model are centered to eliminate non-essential multicollinearity, a variety of common models, representing both ordinal and disordinal interactions, are shown to have "orientations" that are favorable to…

  11. Oak Ridge Leadership Computing Facility (OLCF)

    Data.gov (United States)

    Federal Laboratory Consortium — The Oak Ridge Leadership Computing Facility (OLCF) was established at Oak Ridge National Laboratory in 2004 with the mission of standing up a supercomputer 100 times...

  12. Pelvic alveolar rhabdomyosarcoma in a young adult

    Directory of Open Access Journals (Sweden)

    David Reisner, MD

    2014-01-01

    Full Text Available Rhabdomyosarcomas are soft-tissue tumors, rare in adults. Accounting for nearly 5% of childhood cancers, they represent less than 0.03% of adult malignancies (1, 2. Three different subtypes of rhabdomyosarcoma have been described (embryonal, alveolar and pleomorphic, making up approximately 50%, 30%, and 20% of the cases, respectively (3. Although the definitive diagnosis is made pathologically, some distinguishing features among these subtypes, and between rhabdomyosarcomas and other soft-tissue tumors, can be suggested on MRI and CT. We present an interesting case of a 20-year-old female with a locally aggressive pelvic alveolar rhabdomyosarcoma. While the prognosis has improved with newer treatment techniques, overall survival rates remain poor. Our case study presents typical features of a rare disease, which can often present a diagnostic dilemma for clinicians.

  13. Dephasing and diffusion on the alveolar surface

    Science.gov (United States)

    Buschle, L. R.; Kurz, F. T.; Kampf, T.; Wagner, W. L.; Duerr, J.; Stiller, W.; Konietzke, P.; Wünnemann, F.; Mall, M. A.; Wielpütz, M. O.; Schlemmer, H. P.; Ziener, C. H.

    2017-02-01

    We propose a surface model of spin dephasing in lung tissue that includes both susceptibility and diffusion effects to provide a closed-form solution of the Bloch-Torrey equation on the alveolar surface. The nonlocal susceptibility effects of the model are validated against numerical simulations of spin dephasing in a realistic lung tissue geometry acquired from synchotron-based μ CT data sets of mouse lung tissue, and against simulations in the well-known Wigner-Seitz model geometry. The free induction decay is obtained in dependence on microscopic tissue parameters and agrees very well with in vivo lung measurements at 1.5 Tesla to allow a quantification of the local mean alveolar radius. Our results are therefore potentially relevant for the clinical diagnosis and therapy of pulmonary diseases.

  14. Silver Nanoparticles in Alveolar Bone Surgery Devices

    Directory of Open Access Journals (Sweden)

    Stefano Sivolella

    2012-01-01

    Full Text Available Silver (Ag ions have well-known antimicrobial properties and have been applied as nanostrategies in many medical and surgical fields, including dentistry. The use of silver nanoparticles (Ag NPs may be an option for reducing bacterial adhesion to dental implant surfaces and preventing biofilm formation, containing the risk of peri-implant infections. Modifying the structure or surface of bone grafts and membranes with Ag NPs may also prevent the risk of contamination and infection that are common when alveolar bone augmentation techniques are used. On the other hand, Ag NPs have revealed some toxic effects on cells in vitro and in vivo in animal studies. In this setting, the aim of the present paper is to summarize the principle behind Ag NP-based devices and their clinical applications in alveolar bone and dental implant surgery.

  15. [Alveolar haemorrhage following a cannabis water pipe].

    Science.gov (United States)

    Moatemri, Z; Zaibi, H; Dabboussi, S; Mhamedi, S; Aichaouia, C; Khadhraoui, M; Cheikh, R

    2016-10-01

    Respiratory toxicity of cannabis is well-known today particularly with the new consumption patterns. We report the case of a 25-year-old man admitted for haemoptysis, with unfavourable outcome and acute respiratory failure. Various explorations concluded to acute respiratory distress syndrome secondary to diffuse alveolar haemorrhage. Etiological assessment was initially negative. Outcome was favourable during hospitalization, authorizing the discharge of our patient. Two days later, alveolar haemorrhage recur, with positive toxicological tests for cannabis and the patient admits smoking cannabis by plastic "bang". We illustrate, through this case, the severity of respiratory complications caused by new methods of using cannabis, particularly with plastic 'bang', hence the need to insist of the importance of supported withdrawal and to inform young people how these techniques are serious.ssss. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  16. Bmp2 and Bmp4 accelerate alveolar bone development.

    Science.gov (United States)

    Ou, Mingming; Zhao, Yibing; Zhang, Fangming; Huang, Xiaofeng

    2015-06-01

    Alveolar bone remodeling is a continuous process that takes place during development and in response to various physiological and pathological stimuli. However, detailed knowledge regarding the underlying mechanisms involved in alveolar bone development is still lacking. This study aims at improving our understanding of alveolar bone formation and the role of bone morphogenetic proteins (Bmps) in this process. Mice at embryonic (E) day 13.5 to postnatal (PN) day 15.5 were selected to observe the process of alveolar bone development. Alveolar bone development was found to be morphologically observable at E14.5. Molar teeth isolated from mice at PN7.5 were pretreated with Bmp2, Bmp4, Noggin, or BSA, and grafted subcutaneously into mice. The subcutaneously implanted tooth germs formed alveolar bone indicating the role of the dental follicle in alveolar bone development. Alveolar bone formation was increased after pretreatment with Bmp2 and Bmp4, but not with Noggin. Gene expression levels in dental follicle cells from murine molars were also determined by real-time RT-PCR. The expression levels of Runx2, Bsp, and Ocn were significantly higher in dental follicle cells cultured with Bmp2 or Bmp4, and significantly lower in those cultured with Noggin when compared with that of the BSA controls. Our results suggest that the dental follicle participates in alveolar bone formation and Bmp2/4 appears to accelerate alveolar bone development.

  17. Phagocytic properties of lung alveolar wall cells

    Directory of Open Access Journals (Sweden)

    Tanaka,Akisuke

    1974-04-01

    Full Text Available For the purpose to define the mechanism of heavy metal intoxication by inhalation, morphologic observations were made on rat lungs after nasal instillation of iron colloid particles of positive and negative electric charges. Histochemical observation was also made on the liver and spleen of these animals. The instilled iron colloid particles reach the alveolar cavity easily, as can be seen in the tissue sections stained by Prussian blue reaction. Alveolar macrophages do take up them avidly both of positive and negative charges, though much less the positive particles than negative ones. In contrast, the alveolar epithelial cells take up solely positive particles by phagocytosis but not negative ones. Electron microscope observation revealed that the positive particles are ingested by Type I epithelial cells by pinocytosis and by Type II cells by phagocytosis as well. Then the iron colloid particles are transferred into the basement membrane by exocytosis. Travelling through the basement membrane they are again taken up by capillary endothelial cells by phagocytosis. Some particles were found in the intercellular clefts of capillary endothelial cells but not any iron colloid particles in the intercellular spaces of epithelial cells and in the capillary lumen. However, the liver and spleen tissues of the animals given iron colloid showed a strong positive iron reaction. On the basis of these observations, the mechanism of acute intoxication by inhaling heavy metal dusts like lead fume is discussed from the view point of selective uptake of alveolar epithelial and capillary endothelial cells for the particles of the positive electric cha'rge.

  18. InRidge program: Preliminary results from the first cruise

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R.; Murthy, K.S.R.; Iyer, S.D.; Rao, M.M.M.; Banerjee, R.; Subrahmanyam, A.S.; Shirodkar, P.V.; Ghose, I.

    The first cruise under India's own Ridge research initiative, InRidge collected new data on bathymetry, free-air gravity and magnetic anomalies across the ridge axis between the Vema and Zhivago transform faults in the Central Indian Ridge...

  19. Inferior alveolar nerve injuries associated with mandibular fractures.

    Science.gov (United States)

    Bede, Salwan Yousif Hanna; Ismael, Waleed Khaleel; Al-Assaf, Dhuha A; Omer, Saad Salem

    2012-11-01

    The study evaluates the incidence of inferior alveolar nerve injuries in mandibular fractures, the duration of their recovery, and the factors associated with them. Fifty-two patients with mandibular fractures involving the ramus, angle, and body regions were included in this study; the inferior alveolar nerve was examined for neurological deficit posttraumatically using sharp/blunt differentiation method, and during the follow-up period the progression of neural recovery was assessed. The incidence of neural injury of the inferior alveolar nerve was 42.3%, comminuted and displaced linear fractures were associated with higher incidence of inferior alveolar nerve injury and prolonged recovery time, and recovery of inferior alveolar nerve function occurred in 91%.Fractures of the mandible involving the ramus, angle, and body regions, and comminuted and displaced linear fractures are factors that increase the incidence of inferior alveolar nerve injuries. Missile injuries can be considered as another risk factor.

  20. Sex Determination from Fingerprint Ridge Density

    Directory of Open Access Journals (Sweden)

    Dr. Sudesh Gungadin

    2007-07-01

    Full Text Available This study was conducted with an aim to establish a relationship between sex and fingerprint ridge density. The fingerprints were taken from 500 subjects (250 males and 250 females in the age group of 18-60 years. After taking fingerprints, the ridges were counted in the upper portion of the radial border of each print for all ten fingers and mean value was calculated. The results have shown that a finger print ridge of 14 ridges/25 mm2 is more likely of female origin. It has been successful to support the hypothesis that women tend to have a statistically significant greater ridge density than men.

  1. PERFORATION OF INFERIOR ALVEOLAR NERVE BY MAXILLARY ARTERY. Perforation of inferior alveolar nerve by maxillary artery

    Directory of Open Access Journals (Sweden)

    Prakash B Billakanti

    2016-03-01

    Full Text Available La fosa infratemporal es un área anatómica clínicamente importante para la administración de agentes anestésicos locales en odontología y cirugía maxilofacial. Fueron estudiadas variaciones en la anatomía del nervio alveolar inferior y la arteria maxilar en la disección infratemporal. Durante la disección rutinaria de la cabeza en el cadáver de un varón adulto, fue observada una variación excepcional en el origen del nervio alveolar inferior y su relación con las estructuras circundantes. El nervio alveolar inferior se originaba en el nervio mandibular por dos raíces y la primera parte de la arteria maxilar estaba incorporada entre ambas. El origen embriológico de esta variación y sus implicaciones clínicas es debatido. Dado que la arteria maxilar transcurría entre las dos raíces del nervio alveolar inferior, y el nervio estaba fijado entre el foramen oval y el foramen mandibular, el atrapamiento vásculo-nervioso pudo causar entume-cimiento o dolor de cabeza e interferir con la inyección de anestésicos locales en la fosa infratemporal.  Variaciones anatómicas en esta región deben ser tenidas en cuenta, especialmente en casos de tratamiento fallido de neuralgia del trigémino. Infratemporal fossa is clinically important anatomical area for the delivery of local anesthetic agents in dentistry and maxillofacial surgery. Variations in the anatomy of the inferior alveolar nerve and maxillary artery were studied in infratemporal dissection. During routine dissection of the head in an adult male cadaver an unusual variation in the origin of the inferior alveolar nerve and its relationship with the surrounding structures was observed. The inferior alveolar nerve originated from the mandibular nerve by two roots and the first part of the maxillary artery was incorporated between them. An embryologic origin of this variation and its clinical implications is discussed. Because the maxillary artery runs between the two roots of

  2. Recent advances in alveolar biology: some new looks at the alveolar interface.

    Science.gov (United States)

    Possmayer, Fred; Hall, Stephen B; Haller, Thomas; Petersen, Nils O; Zuo, Yi Y; Bernardino de la Serna, Jorge; Postle, Anthony D; Veldhuizen, Ruud A W; Orgeig, Sandra

    2010-08-31

    This article examines the manner in which some new methodologies and novel concepts have contributed to our understanding of how pulmonary surfactant reduces alveolar surface tension. Investigations utilizing small angle X-ray diffraction, inverted interface fluorescence microscopy, time of flight-secondary ion mass spectroscopy, atomic force microscopy, two-photon fluorescence microscopy and electrospray mass spectroscopy are highlighted and a new model of ventilation-induced acute lung injury described. This contribution attempts to emphasize how these new approaches have resulted in a fuller appreciation of events presumably occurring at the alveolar interface. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  3. Melanocortin agonism as a viable strategy to control alveolar bone loss induced by oral infection.

    Science.gov (United States)

    Madeira, Mila F M; Queiroz-Junior, Celso M; Montero-Melendez, Trinidad; Werneck, Silvia M C; Corrêa, Jôice D; Soriani, Frederico M; Garlet, Gustavo P; Souza, Daniele G; Teixeira, Mauro M; Silva, Tarcilia A; Perretti, Mauro

    2016-12-01

    Alveolar bone loss is a result of an aggressive form of periodontal disease (PD) associated with Aggregatibacter actinomycetemcomitans (Aa) infection. PD is often observed with other systemic inflammatory conditions, including arthritis. Melanocortin peptides activate specific receptors to exert antiarthritic properties, avoiding excessing inflammation and modulating macrophage function. Recent work has indicated that melanocortin can control osteoclast development and function, but whether such protection takes place in infection-induced alveolar bone loss has not been investigated. The purpose of this study was to evaluate the role of melanocortin in Aa-induced PD. Mice were orally infected with Aa and treated with the melanocortin analog DTrp(8)-γMSH or vehicle daily for 30 d. Then, periodontal tissue was collected and analyzed. Aa-infected mice treated with DTrp(8)-γMSH presented decreased alveolar bone loss and a lower degree of neutrophil infiltration in the periodontium than vehicle-treated animals; these actions were associated with reduced periodontal levels of TNF-α, IFN-γ, and IL-17A. In vitro experiments with cells differentiated into osteoclasts showed that osteoclast formation and resorptive activity were attenuated after treatment with DTrp(8)-γMSH. Thus, melanocortin agonism could represent an innovative way to tame overexuberant inflammation and, at the same time, preserve bone physiology, as seen after Aa infection.-Madeira, M. F. M., Queiroz-Junior, C. M., Montero-Melendez, T., Werneck, S. M. C., Corrêa, J. D., Soriani, F. M., Garlet, G. P., Souza, D. G., Teixeira, M. M., Silva, T. A., Perretti, M. Melanocortin agonism as a viable strategy to control alveolar bone loss induced by oral infection. © FASEB.

  4. The role of synthetic biomaterials in resorptive alveolar bone regeneration

    OpenAIRE

    2007-01-01

    The alveolar bone tissue resorption defect has a significant role in dentistry. Because of the bone tissue deficit developed by alveolar resorption, the use of synthetic material CP/PLGA (calcium-phosphate/polylactide-co-gliycolide) composite was introduced. Investigations were performed on rats with artificially produced resorption of the mandibular bone. The results show that the best effect on alveolar bone were attained by using nano-composite implants. The effect of the nanocomposite was...

  5. Prevalence and location of the posterior superior alveolar artery using cone-beam computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Tehranchi, Maryam; Taleghani, Ferial; Shahab, Shahriar [Faculty of Dentistry, Shahed University, Tehran (Iran, Islamic Republic of); Nouri, Arash [Nouri' s Dental Clinic, Tehran (Iran, Islamic Republic of)

    2017-03-15

    Insufficient knowledge of the anatomy of the maxillary sinuses prior to sinus graft surgery may lead to perioperative or postoperative complications. This study sought to characterize the position of the posterior superior alveolar artery (PSAA) within the maxillary sinuses using cone-beam computed tomography (CBCT). A total of 300 patients with edentulous posterior maxillae, including 138 females and 162 males with an age range of 33-86 years, who presented to a radiology clinic between 2013 and 2015 were enrolled in this retrospective cross-sectional study. The distance from the inferior border of the PSAA to the alveolar crest according to the residual ridge classification by Lekholm and Zarb, the distance from the PSAA to the nasal septum and zygomatic arch, and the diameter and position of the PSAA were all assessed on patients' CBCT scans. The data were analyzed using the Mann-Whitney test and the t-test. The PSAA was detected on the CBCT scans of 87% of the patients; it was located beneath the sinus membrane in 47% of cases and was intraosseous in 47% of cases. The diameter of the artery was between 1 and 2 mm in most patients (72%). The mean diameter of the artery was 1.29±0.39 mm, and the mean distances from the PSAA to the zygomatic arch, nasal septum, and alveolar crest were 22.59±4.89 mm, 26.51±3.52 mm, and 16.7±3.96 mm, respectively. The likelihood of detecting the PSAA on CBCT scans is high; its location is intraosseous or beneath the sinus membrane in most patients. Determining the exact location of the PSAA on CBCT scans preoperatively can help prevent it from being damaged during surgery.

  6. Prevalence and location of the posterior superior alveolar artery using cone-beam computed tomography

    Science.gov (United States)

    Tehranchi, Maryam; Shahab, Shahriar; Nouri, Arash

    2017-01-01

    Purpose Insufficient knowledge of the anatomy of the maxillary sinuses prior to sinus graft surgery may lead to perioperative or postoperative complications. This study sought to characterize the position of the posterior superior alveolar artery (PSAA) within the maxillary sinuses using cone-beam computed tomography (CBCT). Materials and Methods A total of 300 patients with edentulous posterior maxillae, including 138 females and 162 males with an age range of 33-86 years, who presented to a radiology clinic between 2013 and 2015 were enrolled in this retrospective cross-sectional study. The distance from the inferior border of the PSAA to the alveolar crest according to the residual ridge classification by Lekholm and Zarb, the distance from the PSAA to the nasal septum and zygomatic arch, and the diameter and position of the PSAA were all assessed on patients' CBCT scans. The data were analyzed using the Mann-Whitney test and the t-test. Results The PSAA was detected on the CBCT scans of 87% of the patients; it was located beneath the sinus membrane in 47% of cases and was intraosseous in 47% of cases. The diameter of the artery was between 1 and 2 mm in most patients (72%). The mean diameter of the artery was 1.29±0.39 mm, and the mean distances from the PSAA to the zygomatic arch, nasal septum, and alveolar crest were 22.59±4.89 mm, 26.51±3.52 mm, and 16.7±3.96 mm, respectively. Conclusion The likelihood of detecting the PSAA on CBCT scans is high; its location is intraosseous or beneath the sinus membrane in most patients. Determining the exact location of the PSAA on CBCT scans preoperatively can help prevent it from being damaged during surgery. PMID:28361028

  7. Uncomplicated impression techniques for hypermobile alveolar mucosa: A hope for the hopeless

    Directory of Open Access Journals (Sweden)

    Prince Kumar

    2012-01-01

    Full Text Available Context: Alveolar mucosa over the jaw bones in edentulous patients has varying thickness and mobility at different areas and is often imprecise at the time of impression making. Such impressions in the finished dentures cause inflammation and instability of the complete dentures. Aim: To present three methods for selective pressure impressions for complete denture treatment in patients who had different kinds of localization and abnormalities of the thickness of alveolar ridges mucosa. Materials and Methods: Three different impression techniques were used for selective pressure impressions in 15 completely edentulous patients based on the location of flabby tissue and special tray modifications. The patients expressed comfort and satisfaction during the usage of the new dentures, compared with the previous one fabricated with the new impression technique. Conclusion: The suggested methods eliminate the excessive displacement of the soft tissues at the secondary impression; thus, a physiologic and anatomic registration of the attached and the unattached tissue of the denture-bearing areas is attained.

  8. Status of Blue Ridge Reservoir

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-01

    This is one in a series of reports prepared by the Tennessee Valley Authority (TVA) for those interested in the conditions of TVA reservoirs. This overview of Blue Ridge Reservoir summarizes reservoir and watershed characteristics, reservoir uses and use impairments, water quality and aquatic biological conditions, and activities of reservoir management agencies. This information was extracted from the most current reports and data available, as well as interview with water resource professionals in various federal, state, and local agencies. Blue Ridge Reservoir is a single-purpose hydropower generating project. When consistent with this primary objective, the reservoir is also operated to benefit secondary objectives including water quality, recreation, fish and aquatic habitat, development of shoreline, aesthetic quality, and other public and private uses that support overall regional economic growth and development. 8 refs., 1 fig.

  9. Reconstruction of maxillary ridge atrophy caused by dentoalveolar trauma, using autogenous block bone graft harvested from chin: a case report

    Directory of Open Access Journals (Sweden)

    Francisley Ávila Souza

    2014-06-01

    Full Text Available Background: Dentoalveolar trauma, especially when involving front teeth, negatively affect the patient’s life; in particular, tooth avulsion is a complex injury that affects multiple tissues, and no treatment option offers stable long-term outcomes. The aim of this study was to report a case of reconstruction of atrophic anterior alveolar ridge after tooth loss, performed with autograft harvested from the chin, and subsequent prosthetic rehabilitation with the use of an osseointegrated implant. Case report: A 23-years-old Caucasian girl, presented an atrophic alveolar bone in the area of tooth 11, as a result of tooth resorption 10 years after a tooth reimplantation procedure. Reconstruction was performed with autogenous bone harvested from the chin. After 6-months healing period to allow autograft incorporation, a dental implant was inserted. After further 6- months, a screw-retained implant supported metal-ceramic prosthesis was fabricated. Results The prosthetic rehabilitation was successful, and after a follow-up period of 5 years, the achieved result was stable. Conclusion: It can be concluded that the autogenous bone graft harvested from the chin, is a safe and effective option for alveolar ridge defects reconstruction, allowing a subsequent placement of a dental implant supporting a prosthetic restoration.

  10. Bose enhancement and the ridge

    Energy Technology Data Exchange (ETDEWEB)

    Altinoluk, Tolga [Departamento de Física de Partículas and IGFAE, Universidade de Santiago de Compostela, 15706 Santiago de Compostela, Galicia (Spain); Armesto, Néstor, E-mail: nestor.armesto@usc.es [Departamento de Física de Partículas and IGFAE, Universidade de Santiago de Compostela, 15706 Santiago de Compostela, Galicia (Spain); Beuf, Guillaume [Department of Physics, Ben-Gurion University of the Negev, Beer Sheva 84105 (Israel); Kovner, Alex [Physics Department, University of Connecticut, 2152 Hillside Road, Storrs, CT 06269-3046 (United States); Lublinsky, Michael [Department of Physics, Ben-Gurion University of the Negev, Beer Sheva 84105 (Israel)

    2015-12-17

    We point out that Bose enhancement in a hadronic wave function generically leads to correlations between produced particles. We show explicitly, by calculating the projectile density matrix in the Color Glass Condensate approach to high-energy hadronic collisions, that the Bose enhancement of gluons in the projectile leads to azimuthal collimation of long range rapidity correlations of the produced particles, the so-called ridge correlations.

  11. Oak Ridge National Laboratory Review

    Energy Technology Data Exchange (ETDEWEB)

    Krause, C.; Pearce, J.; Zucker, A. (eds.)

    1992-01-01

    This report presents brief descriptions of the following programs at Oak Ridge National Laboratory: The effects of pollution and climate change on forests; automation to improve the safety and efficiency of rearming battle tanks; new technologies for DNA sequencing; ORNL probes the human genome; ORNL as a supercomputer research center; paving the way to superconcrete made with polystyrene; a new look at supercritical water used in waste treatment; and small mammals as environmental monitors.

  12. Bose enhancement and the ridge

    CERN Document Server

    Altinoluk, Tolga; Beuf, Guillaume; Kovner, Alex; Lublinsky, Michael

    2015-01-01

    We point out that Bose enhancement in a hadronic wave function generically leads to correlations between produced particles. We show explicitly, by calculating the projectile density matrix in the Color Glass Condensate approach to high-energy hadronic collisions, that the Bose enhancement of gluons in the projectile leads to azimuthal collimation of long range rapidity correlations of the produced particles, the so-called ridge correlations.

  13. Bose enhancement and the ridge

    Directory of Open Access Journals (Sweden)

    Tolga Altinoluk

    2015-12-01

    Full Text Available We point out that Bose enhancement in a hadronic wave function generically leads to correlations between produced particles. We show explicitly, by calculating the projectile density matrix in the Color Glass Condensate approach to high-energy hadronic collisions, that the Bose enhancement of gluons in the projectile leads to azimuthal collimation of long range rapidity correlations of the produced particles, the so-called ridge correlations.

  14. 牙槽骨劈开术同期牙种植的临床应用%The application of alveolar bone splitting technique with simultaneous implant placement

    Institute of Scientific and Technical Information of China (English)

    周艺群; 洪振华; 程志鹏

    2011-01-01

    Objective The aim of this study was to investigate the application of alveolar bone splitting technique in dental implant,and to evaluate the clinical efficacy.Methods 116 patients were included in this study whose alveolar ridge height all exceeded 12mm, and bucco-lingual alveolar ridge thickness was between 3 and 5 mm.147 ITI implants and 52 Replace implants were placed simultaneously after alveolar ridges splitting.If the gap after splitting was more than 1 mm, the thickness of labial alveolar bone was less than 1 mm, or labial bone defect existed in the root area of implant, bone substitute grafting and guide bone regeneration technique would be used.Superstructures were restored 6 months after implant placement, and regular follow-ups were done.Results The soft tissue in the surgical area healed well and no swelling existed.The buccolingual alveolar ridges were obviously widened.Except that one implant failed, all implants were stable and functioned well.X-rays showed marginal bone loss were less than 1 mm.Conclusions Bone splitting technique was a simple and effective method for alveolar bone augmentation, and it made it possible for those patients whose alveolar ridges thickness was between 3-5mm to take a one-stage implant placement surgery.%目的 评价牙槽骨劈开技术在口腔种植中应用的临床效果.方法 对116例缺牙区牙槽嵴高度大于12 mm,颊舌向厚度在3~5mm之间的牙列缺损患者,行牙槽嵴劈开同期植入种植体治疗.共植入ITI种植体147枚,Replace种植体52枚.根据骨劈开术后间隙及唇颊侧骨壁厚度等不同情况选择植入或不植入自体骨、人工骨粉等修复手段.术后6月种植修复,定期随诊.结果 种植区软组织愈合好,无红肿,颊舌向牙槽骨较种植前明显增宽.术后除1颗种植体失败取出外,其余种植体稳固,种植修复体能正常使用.复诊时X线检查骨吸收≤1 mm.结论 骨劈开术使牙槽骨宽度在3~5 mm的病例有了一期种

  15. PERFORATION OF INFERIOR ALVEOLAR NERVE BY MAXILLARY ARTERY. LA PERFORACION DEL NERVIO ALVEOLAR INFERIOR POR LA ARTERIA MAXILAR

    OpenAIRE

    Vanishree S Nayak; Ramachandra Bhat K; Prakash Billakanti Babu

    2011-01-01

    Infratemporal fossa is clinically important anatomical area for the delivery of local anesthetic agents in dentistry and maxillofacial surgery. Variations in the anatomy of the inferior alveolar nerve and maxillary artery were studied in infratemporal dissection. During routine dissection of the head in an adult male cadaver an unusual variation in the origin of the inferior alveolar nerve and its relationship with the surrounding structures was observed. The inferior alveolar nerve originate...

  16. Geo-Morphological Analyses of the Gakkel Ridge and the Southwest Indian Ridge

    Science.gov (United States)

    Dorschel, B.; Schlindwein, V. S. N.; Eagles, G.

    2014-12-01

    The Gakkel Ridge in the Arctic Ocean and the Southwest Indian Ridge in the Southwest Indian Ocean between Africa and Antarctica are ultraslow-spreading (intersticial melt migration) by which material rises to fill the space vacated by plate divergence. These ridges are characterised by non-orthogonal spreading. Transform faults, typical of faster spreading mid ocean ridges, are far less common at ultraslow spreading mid ocean ridges. Thus in return, detailed geo-statistical analyses of the geo-morphology of ultraslow-spreading mid ocean ridges can provide valuable information towards a better understanding of these slowest of spreading ridges. We have generated high resolution bathymetric grids for the Gakkel and Southwest Indian ridges based on high resolution multibeam echosounder data from various expeditions with RV Polarstern. On the basis of these grids, geo-statistical analyses allow for an assessment of the geo-morphological elements of the ridges on various scales. The results of these analyses show that, approximately 200 km long medium-scale sections of the ridges can be characterised by the lengths and orientations of the short-scale (hundreds of meters to tens of kilometres) ridges and troughs. The geomorphologies of short-scale ridges and troughs situated at the junctions between medium scale sections often exhibit a mixture of the geomorphological elements seen in the neighbouring sections. These geo-morphological patterns provide insights into the overall spreading-geometry along the Gakkel Ridge and the Southwest Indian Ridge.

  17. Segment distraction to reduce a wide alveolar cleft before alveolar bone grafting.

    NARCIS (Netherlands)

    Binger, T.; Katsaros, C.; Rucker, M.; Spitzer, W.J.

    2003-01-01

    OBJECTIVE: To demonstrate a method for reduction of wide alveolar clefts prior to bone grafting. This method aims to facilitate bone grafting and achieve adequate soft tissue coverage of the graft with attached gingiva. CASE REPORT: Treatment of a patient with bilateral cleft lip and palate with a s

  18. Recent advances in alveolar biology: Evolution and function of alveolar proteins

    NARCIS (Netherlands)

    Orgeig, S.; Hiemstra, P.S.; Veldhuizen, E.J.A.; Casals, C.; Clark, H.W.; Hackzu, A.; Knudsen, L.; Possmayer, F.

    2010-01-01

    This review is focused on the evolution and function of alveolar proteins. The lung faces physical and environmental challenges, due to changing pressures/volumes and foreign pathogens, respectively. The pulmonary surfactant system is integral in protecting the lung from these challenges via two gro

  19. Wildlife Management Plan for the Oak Ridge Reservation

    Energy Technology Data Exchange (ETDEWEB)

    Giffen, Neil R [ORNL; Evans, James W. [TWRA; Parr, Patricia Dreyer [ORNL

    2007-10-01

    This document outlines a plan for management of the wildlife resources on the Department of Energy's (DOE's) Oak Ridge Reservation. Management includes wildlife population control through hunting, trapping, removal, and habitat manipulation; wildlife damage control; restoration of wildlife species; preservation, management, and enhancement of wildlife habitats; coordination of wildlife studies and characterization of areas; and law enforcement. Wildlife resources are divided into several categories, each with a specific set of objectives and procedures for attaining them. These objectives are management of (1) wildlife habitats to ensure that all resident wildlife species exist on the Reservation in viable numbers; (2) featured species to produce selected species in desired numbers on designated land units; (3) game species for research, education, recreation, and public safety; (4) the Three Bend Scenic and Wildlife Management Refuge Area; (5) nuisance wildlife, including nonnative species, to achieve adequate population control for the maintenance of health and safety on the Reservation; (6) sensitive species (i.e., state or federally listed as endangered, threatened, of special concern, or in need of management) through preservation and protection of both the species and habitats critical to the survival of those species; and (7) wildlife disease. Achievement of the objectives is a joint effort between the Tennessee Wildlife Resources Agency (TWRA) and the Oak Ridge National Laboratory through agreements between TWRA and DOE and between DOE and UT-Battelle, LLC.

  20. Resource management plan for the Oak Ridge Reservation

    Energy Technology Data Exchange (ETDEWEB)

    Parr, P.D. (Oak Ridge National Lab., TN (United States)); Evans, J.W. (Tennessee Wildlife Resources Agency, Knoxville, TN (United States))

    1992-06-01

    A plan for management of the wildlife resources on the US Department of Energy's Oak Ridge Reservation is outlined in this document. Management includes wildlife population control (hunts, trapping, and removal), handling specific problems with wildlife, restoration of species, coordination with researchers on wildlife studies, preservation and management of habitats, and law enforcement. Wildlife resources are divided into five categories, each with a specific set of objectives and procedures for obtaining these objectives. These categories are (1) species-richness management to ensure that all resident wildlife species exist on the Reservation in viable numbers; (2) featured species management to produce selected species in desired numbers on designated land units; (3) management of game species for research, education, recreation, and public safety, (4) endangered species management designed to preserve and protect both the species and habitats critical to the survival of those species; and (5) pest management. Achievement of the objectives is a joint effort between the Tennessee Wildlife Resources Agency and the Oak Ridge National Laboratory's Environmental Sciences Division.

  1. DMPD: Silica binding and toxicity in alveolar macrophages. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18226603 Silica binding and toxicity in alveolar macrophages. Hamilton RF Jr, Thaku...l) Show Silica binding and toxicity in alveolar macrophages. PubmedID 18226603 Title Silica binding and toxicity in alveolar

  2. Decompression of inferior alveolar nerve: case report.

    Science.gov (United States)

    Marques, Tiago Miguel Santos; Gomes, Joana Marques

    2011-01-01

    Paresthesia as a result of mechanical trauma is one of the most frequent sensory disturbances of the inferior alveolar nerve. This case report describes surgical treatment for paresthesia caused by a compressive phenomenon within the mandibular canal. The cause of the compression, a broken instrument left in the patient's mouth during previous endodontic therapy, was identified during routine radiography and computed tomography. Once the foreign object was removed by surgery, the paresthesia resolved quickly. This case highlights the potential for an iatrogenic mechanical cause of paresthesia.

  3. Soil physics and chemistry at a medieval ridge and furrow site in northeastern Germany

    Science.gov (United States)

    Hirsch, Florian; van der Maaten-Theunissen, Marieke; van der Maaten, Ernst; Schneider, Anna; Raab, Alexandra; Raab, Thomas

    2017-04-01

    The usage of non-reversible ploughs, mainly during the Middle Ages and until historic times, led to the formation of ridge and furrow systems. Due to improvements of agricultural techniques, these historic agricultural sites were often abandoned and are now marginal land. The parallel ridges and furrows are usually, if not destroyed by later conventional ploughing, preserved in present-day forests. In northeastern Germany ridge and furrow systems are normally several decameters long and up to ten meters wide. The height difference between ridge top and furrow bottom is up to 50 centimeters and is expected to cause significant contrasts of soil properties and vegetation. Furthermore, due to the abandonment of sites with ridges and furrows, soils on these sites are unique archives for studies on fertilization, soil carbon dynamics and soil development. Therefore, we are characterizing soil physics (bulk density, saturated soil hydraulic conductivity, texture) and soil chemistry (soil acidity, carbon and nitrogen content) on a type location of historic ridges and furrows about 100 km northwest of Berlin.

  4. Nostril Base Augmentation Effect of Alveolar Bone Graft

    Directory of Open Access Journals (Sweden)

    Woojin Lee

    2013-09-01

    Full Text Available Background The aims of alveolar bone grafting are closure of the fistula, stabilization ofthe maxillary arch, support for the roots of the teeth adjacent to the cleft on each side.We observed nostril base augmentation in patients with alveolar clefts after alveolar bonegrafting. The purpose of this study was to evaluate the nostril base augmentation effect ofsecondary alveolar bone grafting in patients with unilateral alveolar cleft.Methods Records of 15 children with alveolar clefts who underwent secondary alveolar bonegrafting with autogenous iliac cancellous bone between March of 2011 and May of 2012 werereviewed. Preoperative and postoperative worm’s-eye view photographs and reconstructedthree-dimensional computed tomography (CT scans were used for photogrammetry. Thedepression of the nostril base and thickness of the philtrum on the cleft side were measuredin comparison to the normal side. The depression of the cleft side pyriform aperture wasmeasured in comparison to the normal side on reconstructed three-dimensional CT.Results Significant changes were seen in the nostril base (P=0.005, the philtrum length(P=0.013, and the angle (P=0.006. The CT measurements showed significant changes in thepyriform aperture (P<0.001 and the angle (P<0.001.Conclusions An alveolar bone graft not only fills the gap in the alveolar process but alsoaugments the nostril base after surgery. In this study, only an alveolar bone graft was performedto prevent bias from other procedures. Nostril base augmentation can be achieved byperforming alveolar bone grafts in children, in whom invasive methods are not advised.

  5. Nostril Base Augmentation Effect of Alveolar Bone Graft

    Directory of Open Access Journals (Sweden)

    Woojin Lee

    2013-09-01

    Full Text Available BackgroundThe aims of alveolar bone grafting are closure of the fistula, stabilization of the maxillary arch, support for the roots of the teeth adjacent to the cleft on each side. We observed nostril base augmentation in patients with alveolar clefts after alveolar bone grafting. The purpose of this study was to evaluate the nostril base augmentation effect of secondary alveolar bone grafting in patients with unilateral alveolar cleft.MethodsRecords of 15 children with alveolar clefts who underwent secondary alveolar bone grafting with autogenous iliac cancellous bone between March of 2011 and May of 2012 were reviewed. Preoperative and postoperative worm's-eye view photographs and reconstructed three-dimensional computed tomography (CT scans were used for photogrammetry. The depression of the nostril base and thickness of the philtrum on the cleft side were measured in comparison to the normal side. The depression of the cleft side pyriform aperture was measured in comparison to the normal side on reconstructed three-dimensional CT.ResultsSignificant changes were seen in the nostril base (P=0.005, the philtrum length (P=0.013, and the angle (P=0.006. The CT measurements showed significant changes in the pyriform aperture (P<0.001 and the angle (P<0.001.ConclusionsAn alveolar bone graft not only fills the gap in the alveolar process but also augments the nostril base after surgery. In this study, only an alveolar bone graft was performed to prevent bias from other procedures. Nostril base augmentation can be achieved by performing alveolar bone grafts in children, in whom invasive methods are not advised.

  6. Removing the remaining ridges in fingerprint segmentation

    Institute of Scientific and Technical Information of China (English)

    ZHU En; ZHANG Jian-ming; YIN Jian-ping; ZHANG Guo-min; HU Chun-feng

    2006-01-01

    Fingerprint segmentation is an important step in fingerprint recognition and is usually aimed to identify non-ridge regions and unrecoverable low quality ridge regions and exclude them as background so as to reduce the time expenditure of image processing and avoid detecting false features. In high and in low quality ridge regions, often are some remaining ridges which are the afterimages of the previously scanned finger and are expected to be excluded from the foreground. However, existing segmentation methods generally do not take the case into consideration, and often, the remaining ridge regions are falsely classified as foreground by segmentation algorithm with spurious features produced erroneously including unrecoverable regions as foreground. This paper proposes two steps for fingerprint segmentation aimed at removing the remaining ridge region from the foreground. The non-ridge regions and unrecoverable low quality ridge regions are removed as background in the first step, and then the foreground produced by the first step is further analyzed for possible remove of the remaining ridge region. The proposed method proved effective in avoiding detecting false ridges and in improving minutiae detection.

  7. Tongue-Palate Contact of Perceptually Acceptable Alveolar Stops

    Science.gov (United States)

    Lee, Alice; Gibbon, Fiona E.; O'Donovan, Cliona

    2013-01-01

    Increased tongue-palate contact for perceptually acceptable alveolar stops has been observed in children with speech sound disorders (SSD). This is a retrospective study that further investigated this issue by using quantitative measures to compare the target alveolar stops /t/, /d/ and /n/ produced in words by nine children with SSD (20 tokens of…

  8. Estrogen regulates pulmonary alveolar formation, loss, and regeneration in mice.

    Science.gov (United States)

    Massaro, Donald; Massaro, Gloria Decarlo

    2004-12-01

    Lung tissue elastic recoil and the dimension and number of pulmonary gas-exchange units (alveoli) are major determinants of gas-exchange function. Loss of gas-exchange function accelerates after menopause in the healthy aged and is progressively lost in individuals with chronic obstructive pulmonary disease (COPD). The latter, a disease of midlife and later, though more common in men than in women, is a disease to which women smokers and never smokers may be more susceptible than men; it is characterized by diminished lung tissue elastic recoil and presently irremediable alveolar loss. Ovariectomy in sexually immature rats diminishes the formation of alveoli, and estrogen prevents the diminution. In the present work, we found that estrogen receptor-alpha and estrogen receptor-beta, the only recognized mammalian estrogen receptors, are required for the formation of a full complement of alveoli in female mice. However, only the absence of estrogen receptor-beta diminishes lung elastic tissue recoil. Furthermore, ovariectomy in adult mice results, within 3 wk, in loss of alveoli and of alveolar surface area without a change of lung volume. Estrogen replacement, after alveolar loss, induces alveolar regeneration, reversing the architectural effects of ovariectomy. These studies 1) reveal estrogen receptors regulate alveolar size and number in a nonredundant manner, 2) show estrogen is required for maintenance of already formed alveoli and induces alveolar regeneration after their loss in adult ovariectomized mice, and 3) offer the possibility estrogen can slow alveolar loss and induce alveolar regeneration in women with COPD.

  9. Perawatan Pulpa Gigi Sulung Disertai Abses Dento Alveolar

    OpenAIRE

    2008-01-01

    Abses dento alveolar adalah kumputan pus yang berada pada tulang alveolar sekitar apeks gigi akibat kematian pulpa. Matinya pulpa dapat disebabkan bakteri, trauma, iritasi mekanis, termis maupun kimiawi. Pengaruh bakteri merupakan penyebab kerusakan jaringan pulpa yang terbesar. Perluasan infeksi ke dalam jaringan periapikal dapat melalui foramen apikalke jaringan periodontal sehingga terjadi inflarnasi. Bila virulensi bakteri meningkat disertai rendahnya pertahanan tubuh penderita dapat ...

  10. Reversible transdifferentiation of alveolar epithelial cells.

    Science.gov (United States)

    Danto, S I; Shannon, J M; Borok, Z; Zabski, S M; Crandall, E D

    1995-05-01

    Alveolar epithelial type II (AT2) cells have been thought to be the progenitors of terminally differentiated type I (AT1) cells in the adult animal in vivo. In this study, we used an AT1 cell-specific monoclonal antibody (mAb VIII B2) to investigate expression of the AT1 cell phenotype accompanying reversible changes in expression of the AT2 cell phenotype. AT2 cells were isolated and cultured either on attached collagen gels or on gels detached 1 or 4 days after plating and maintained thereafter as floating gels. Monolayers on both attached and floating gels were harvested on days 4 and 8 and analyzed by electron microscopy for changes in morphology and binding of mAb VIII B2. Results indicate that: (1) alveolar epithelial cells (AEC) on attached gels develop characteristics of the AT1 cell phenotype, (2) AEC on gels detached on day 1 maintain features of the AT2 cell phenotype (and do not react with mAb VIII B2), and (3) the expression of AT1 cell phenotypic traits seen by day 4 on attached gels is reversed after detachment. We conclude that commitment to the AT1 and AT2 cell lineages requires continuous regulatory input to maintain the differentiated states, and that transdifferentiation between AT2 and AT1 cells may be reversible.

  11. Identification of an autophagy defect in smokers' alveolar macrophages.

    Science.gov (United States)

    Monick, Martha M; Powers, Linda S; Walters, Katherine; Lovan, Nina; Zhang, Michael; Gerke, Alicia; Hansdottir, Sif; Hunninghake, Gary W

    2010-11-01

    Alveolar macrophages are essential for clearing bacteria from the alveolar surface and preventing microbe-induced infections. It is well documented that smokers have an increased incidence of infections, in particular lung infections. Alveolar macrophages accumulate in smokers' lungs, but they have a functional immune deficit. In this study, we identify an autophagy defect in smokers' alveolar macrophages. Smokers' alveolar macrophages accumulate both autophagosomes and p62, a marker of autophagic flux. The decrease in the process of autophagy leads to impaired protein aggregate clearance, dysfunctional mitochondria, and defective delivery of bacteria to lysosomes. This study identifies the autophagy pathway as a potential target for interventions designed to decrease infection rates in smokers and possibly in individuals with high environmental particulate exposure.

  12. [Preservatives in ophthalmology].

    Science.gov (United States)

    Messmer, E M

    2012-11-01

    Preservatives are a legal requirement for eye drops in multidose containers. Moreover, they are necessary for stabilization and intraocular penetration for a number of ophthalmic preparations. Most preservatives act in a relatively unspecific manner as detergents or by oxidative mechanisms and thereby cause side effects at the ocular surface. They may also affect the lens, trabecular meshwork and the retina. Benzalkonium chloride is the most commonly used preservative in ophthalmology and is more toxic than other or newer preservatives, such as polyquaternium-1 (Polyquad), sodium perborate, oxychloro-complex (Purite®) and SofZia. Preservative-free topical medication is highly recommended for patients with ocular surface disease, frequent eye drop administration, proven allergy to preservatives and contact lens wear.

  13. Preserving Digital Materials

    CERN Document Server

    Harvey, Ross

    2011-01-01

    This book provides a single-volume introduction to the principles, strategies and practices currently applied by librarians and recordkeeping professionals to the critical issue of preservation of digital information. It incorporates practice from both the recordkeeping and the library communities, taking stock of current knowledge about digital preservation and describing recent and current research, to provide a framework for reflecting on the issues that digital preservation raises in professional practice.

  14. Metallogenesis along the Indian Ocean Ridge System

    Digital Repository Service at National Institute of Oceanography (India)

    Banerjee, R.; Ray, Dwijesh

    active hydrothermal black smoker deposit along this ridge system (Figure 1). The obser - vations summarized here comprise the res ults obtained from the Central Indian Ridge (CIR), Southwest Indian Ridge (SWIR), Southeast Indian Ridge (SEIR), Carlsberg... and appears to be in a tectonic stage of rift development. A hydrothermal plume with maximum concentration of 202 nl/l methane (CH 4 ) and a tempera ture anomaly of + 0.05?C was delineated at 24?03 minuteS (hydro - ther mal plume site). Manganese...

  15. Rituximab therapy in pulmonary alveolar proteinosis improves alveolar macrophage lipid homeostasis

    Directory of Open Access Journals (Sweden)

    Malur Anagha

    2012-06-01

    Full Text Available Abstract Rationale Pulmonary Alveolar Proteinosis (PAP patients exhibit an acquired deficiency of biologically active granulocyte-macrophage colony stimulating factor (GM-CSF attributable to GM-CSF specific autoantibodies. PAP alveolar macrophages are foamy, lipid-filled cells with impaired surfactant clearance and markedly reduced expression of the transcription factor peroxisome proliferator-activated receptor gamma (PPARγ and the PPARγ-regulated ATP binding cassette (ABC lipid transporter, ABCG1. An open label proof of concept Phase II clinical trial was conducted in PAP patients using rituximab, a chimeric murine-human monoclonal antibody directed against B lymphocyte specific antigen CD20. Rituximab treatment decreased anti-GM-CSF antibody levels in bronchoalveolar lavage (BAL fluid, and 7/9 patients completing the trial demonstrated clinical improvement as measured by arterial blood oxygenation. Objectives This study sought to determine whether rituximab therapy would restore lipid metabolism in PAP alveolar macrophages. Methods BAL samples were collected from patients pre- and 6-months post-rituximab infusion for evaluation of mRNA and lipid changes. Results Mean PPARγ and ABCG1 mRNA expression increased 2.8 and 5.3-fold respectively (p ≤ 0.05 after treatment. Lysosomal phospholipase A2 (LPLA2 (a key enzyme in surfactant degradation mRNA expression was severely deficient in PAP patients pre-treatment but increased 2.8-fold post-treatment. In supplemental animal studies, LPLA2 deficiency was verified in GM-CSF KO mice but was not present in macrophage-specific PPARγ KO mice compared to wild-type controls. Oil Red O intensity of PAP alveolar macrophages decreased after treatment, indicating reduced intracellular lipid while extracellular free cholesterol increased in BAL fluid. Furthermore, total protein and Surfactant protein A were significantly decreased in the BAL fluid post therapy. Conclusions Reduction in GM

  16. The Northern Central Indian Ridge: Geology and tectonics of fracture zones-dominated spreading ridge segments

    Digital Repository Service at National Institute of Oceanography (India)

    Drolia, R.K.; Iyer, S.D.; Chakraborty, B.; Kodagali, V.N.; Ray, Dwijesh; Misra, S.; Andrade, R.; Sarma, K.V.L.N.S.; Rajasekhar, R.P.; Mukhopadhyay, R.

    - OCEANIC RIDGES CURRENT SCIENCE, VOL. 85, NO. 3, 10 AUGUST 2003 The Northern Central Indian Ridge: Geology and tectonics of fracture zones - dominated spreading ridge segments R. K. Drolia*, Sridhar D. Iyer ? , B. Chakraborty, V. N. Kodagali, D... anomalies are plotted perpendicular to cruise tracks. SPECIAL SECTION: MID - OCEANIC RIDGES CURRENT SCIENCE, VOL. 85, NO. 3, 10 AUGUST 2003 291 20 ? 18 Ma old and runs along the equator from the CIR in the west to the Wharton Basin in the east...

  17. Papilla Preservation Flap as Aesthetic Consideration in Periodontal Flap Surgery

    Directory of Open Access Journals (Sweden)

    Sandra Olivia

    2013-07-01

    Full Text Available Flap surgery is treatment for periodontal disease with alveolar bone destruction. Surgical periodontal flap with conventional incision will result in gingival recession and loss of interdental papillae after treatment. Dilemma arises in areas required high aesthetic value or regions with a fixed denture. It is challenging to perform periodontal flap with good aesthetic results and minimal gingival recession. This case report aimed to inform and to explain the work procedures, clinical and radiographic outcomes of surgical papilla preservation flap in the area that requires aesthetic. Case 1 was a surgical incision flap with preservation of papillae on the anterior region of teeth 11 and 12, with a full veneer crown on tooth 12. Case 2 was a surgical incision flap with preservation of papillae on the posterior region of tooth 46 with inlay restoration. Evaluation for both cases were obtained by incision papilla preservation of primary closure was perfect, good aesthetic results, minimal gingival recession and the interdental papillae can be maintained properly. In conclusion, periodontal flap surgery on the anterior region or regions that require high aesthetic value could be addressed with papilla preservation incision. Incision papilla preservation should be the primary consideration in periodontal flap surgery if possible.DOI: 10.14693/jdi.v19i3.144

  18. Melt transport rates in heterogeneous mantle beneath mid-ocean ridges

    CERN Document Server

    Weatherley, Samuel M

    2015-01-01

    Recent insights to melt migration beneath ridges suggest that channelized flow is a consequence of melting of a heterogeneous mantle, and that spreading rate modulates the dynamics of the localized flow. A corollary of this finding is that both mantle het- erogeneity and spreading rate have implications for the speed and time scale of melt migration. Here, we investigate these implications using numerical models of magma flow in heterogeneous mantle beneath spreading plates. The models predict that a broad distribution of magma flow speeds is characteristic of the sub-ridge mantle. Within the melting region, magmatic flow is fastest in regions of average fusibility; surprisingly, magmas from sources of above-average fusibility travel to the ridge in a longer time. Spreading rate has comparatively simple consequences, mainly resulting in faster segregation speeds at higher spreading rates. The computed time scales are short enough to preserve deep origin 230Th disequilibria and, under favourable parameter regi...

  19. Alveolar ventilation in children during flexible bronchoscopy.

    Science.gov (United States)

    Sadot, Efraim; Gut, Guy; Sivan, Yakov

    2016-11-01

    Hypoxia and hypercarbia complicate flexible bronchoscopy (FB). Unlike oxygenation by pulse-oximetry, alveolar ventilation is not routinely monitored during FB. The aim of this study was to investigate ventilation in children undergoing FB by measuring carbon-dioxide (CO2 ) levels using the transcutaneous technique. Children admitted for FB were recruited. In addition to routine monitoring, transcutaneous CO2 (TcCO2 ) levels were recorded. All were sedated using the same protocol. Ninety-five children were studied. There was no association between peak TcCO2 or rise in TcCO2 and age, weight percentile, bronchoscope size, or diagnosis. Median baseline TcCO2 was 36 mmHg (IQR 32,40), median peak TcCO2 was 51 mmHg (IQR 43,62) with median TcCO2 rise of 17 mmHg (IQR 6.5,23.7). A rise of 15 mmHg or higher was recorded in 55% (n = 52) patients. Children requiring total propofol dose over 3.5 mg/kg had a significantly higher TcCO2 peak of 57.6 mmHg (IQR 47.8,66.7) compared to 47.1 mmHg (IQR 40,57) (P = 0.004) and a higher rise in TcCO2 22.5 mmHg (IQR 17,33.9) compared to 13.6 mmHg (6,22) (P = 0.001). Results were not affected by intranasal midazolam and broncho-alveolar lavage. No complications were reported. Non clinically significant (i.e., not lower than 90%) brief drops in oxygen saturation were observed. A large proportion of children undergoing FB have significant alveolar hypoventilation indicated by a rise in TcCO2 . Monitoring ventilation with TcCO2 is feasible and should be added during FB particularly in cases that are expected to require large amounts of sedation and patients susceptible to complications from respiratory acidosis. Pediatr Pulmonol. 2016;51:1177-1182. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  20. Submergence of Roots for Alveolar Bone Preservation. I. Endodontically Treated Roots.

    Science.gov (United States)

    1977-05-10

    CARLOS E. del RIO , B.S. , D.D.S. MAJ , DC Periodontic Resident , US Army Inst itute of Denta l Research , Walter Reed Army Medica l Center, Washington... Medica l Center , Washington , DC 20012 ***~COL , DC Chief , Division of Clin ical Research; Director , Endodontic Residency , US Army Institute of...del RIO Di rec tor , Endodontic Residency Chief , Division of Clinica l Research Walter Reed Army Medical Center, = Washington , DC 20012 I

  1. Hemorragia alveolar associada a nefrite lúpica Alveolar hemorrhage associated with lupus nephritis

    Directory of Open Access Journals (Sweden)

    Ricardo Henrique de Oliveira Braga Teixeira

    2003-12-01

    Full Text Available Hemorragia alveolar, como causa de insuficiência respiratória, é pouco freqüente, com diversas etiologias possíveis. Entre elas, o lúpus eritematoso sistêmico, que se apresenta geralmente como síndrome pulmão-rim, possui alta morbimortalidade. Acredita-se que a patogênese da microangiopatia, tanto renal como pulmonar, esteja associada ao depósito de imunocomplexos, que ativariam as vias de apoptose celular. Relatam-se dois casos de pacientes com nefrite lúpica que evoluíram com hemorragia alveolar associada à insuficiência respiratória necessitando de ventilação mecânica com evoluções totalmente distintas frente às terapias farmacológicas. O achado de anticorpos antimembrana basal em um dos casos evidencia a multiplicidade de mecanismos fisiopatológicos possivelmente envolvidos, que poderiam justificar as respostas heterogêneas frente aos tratamentos disponíveis.Alveolar hemorrhage leading to respiratory failure is uncommon. Various etiologies have been reported, including systemic lupus erythematosus, which generally presents as pulmonary-renal syndrome. It is believed that the pathogenesis of microangiopathy is related to deposits of immune complexes that lead to activation of cellular apoptosis. The authors report two cases of alveolar hemorrhage and respiratory failure, both requiring mechanical ventilation. The two cases had opposite outcomes after pharmacological therapy. The presence of anti-glomerular basement membrane antibodies in one of the cases demonstrates the multiplicity of physiopathological mechanisms that may be involved. This multiplicity of mechanisms provides a possible explanation for the heterogeneous responses to the available treatments.

  2. Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.

    Science.gov (United States)

    Dhingra, Kunaal; Prakash, Shobha

    2012-06-01

    Drug-influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine. Its occurrence in both dentate and edentulous regions of oral cavity is poorly understood. This report highlights clinical and histological description, aetiology and management of gingival overgrowth in a partially edentulous (non-denture wearer) 60-year-old female patient with epilepsy on phenytoin and phenobarbital drugs from past 7 years. Patient's intraoral examination revealed lobulated and fibrotic consistency gingival overgrowth around teeth and on partially edentulous ridges of upper and lower arches along with generalised tooth mobility. Under medical consultation, full mouth extraction, surgical excision of overgrowth followed by complete denture rehabilitation and replacement of combination drugs with sodium valproate were accomplished. Histologically, the lesion showed fibro-epithelial hyperplasia. Clinical results after 6 months demonstrated almost complete resolution of gingival overgrowth. The findings of present case suggest that gingival overgrowth can occur even in partially edentulous ridges (not exposed to denture wear) that could be due to persistence of gingival overgrowth, which may not resolve completely following tooth extraction or occurs because of incorporation of specific subpopulation of gingival fibroblasts in alveolar ridge mucosa. © 2012 The Gerodontology Society and John Wiley & Sons A/S.

  3. Mass preserving image registration

    DEFF Research Database (Denmark)

    Gorbunova, Vladlena; Sporring, Jon; Lo, Pechin Chien Pau

    2010-01-01

    The paper presents results the mass preserving image registration method in the Evaluation of Methods for Pulmonary Image Registration 2010 (EMPIRE10) Challenge. The mass preserving image registration algorithm was applied to the 20 image pairs. Registration was evaluated using four different...

  4. Modes of fossil preservation

    Science.gov (United States)

    Schopf, J.M.

    1975-01-01

    The processes of geologic preservation are important for understanding the organisms represented by fossils. Some fossil differences are due to basic differences in organization of animals and plants, but the interpretation of fossils has also tended to be influenced by modes of preservation. Four modes of preservation generally can be distinguished: (1) Cellular permineralization ("petrifaction") preserves anatomical detail, and, occasionally, even cytologic structures. (2) Coalified compression, best illustrated by structures from coal but characteristic of many plant fossils in shale, preserves anatomical details in distorted form and produces surface replicas (impressions) on enclosing matrix. (3) Authigenic preservation replicates surface form or outline (molds and casts) prior to distortion by compression and, depending on cementation and timing, may intergrade with fossils that have been subject to compression. (4) Duripartic (hard part) preservation is characteristic of fossil skeletal remains, predominantly animal. Molds, pseudomorphs, or casts may form as bulk replacements following dissolution of the original fossil material, usually by leaching. Classification of the kinds of preservation in fossils will aid in identifying the processes responsible for modifying the fossil remains of both animals and plants. ?? 1975.

  5. Effectiveness of Lateral Bone Augmentation on the Alveolar Crest Dimension: A Systematic Review and Meta-analysis.

    Science.gov (United States)

    Sanz-Sánchez, I; Ortiz-Vigón, A; Sanz-Martín, I; Figuero, E; Sanz, M

    2015-09-01

    Lateral ridge augmentation procedures are aimed to reconstruct deficient alveolar ridges or to build up peri-implant dehiscence and fenestrations. The objective of this systematic review was to assess the efficacy of these interventions by analyzing data from 40 clinical studies evaluating bone augmentation through either the staged or the simultaneous approach. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guideline for systematic reviews was used. The primary outcomes were the changes at reentry, in the ridge width, and in the vertical and horizontal dimensions of the peri-implant defect, measured in millimeters, in the staged and simultaneous approaches, respectively. The results of the meta-analysis showed, for the simultaneous approach, a statistically significant defect height reduction when all treatments were analyzed together (weighted mean difference [WMD] = -4.28 mm; 95% confidence interval: [CI] -4.88, -3.69; P bone replacement grafts with barrier membranes was associated with superior outcomes The most frequently used intervention was the combination of xenograft and bioabsorbable membrane. Similarly, for the staged approach, there was a statistically significant horizontal gain when all treatment groups were combined (WMD = 3.90 mm; 95% CI: 3.52, 4.28; P bone blocks. Both treatment strategies led to high survival and success rates (>95%) for the implants placed on the regenerated sites. Nonexposed sites gained significantly more in the simultaneous and staged approaches (WMD = 1.1 and 3.1 mm).

  6. Diffuse alveolar hemorrhage due to ketorolac tromethamine.

    Science.gov (United States)

    Marak, Creticus P; Alappan, Narendrakumar; Shim, Chang; Guddati, Achuta K

    2013-01-01

    Drug-induced lung disease (DILD) is a common but frequently missed diagnosis. Therefore, a high index of clinical suspicion and familiarity with the clinical syndromes associated with DILD are important in making the diagnosis. Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the mostly commonly used classes of medications. NSAIDs are safe when used at prescribed doses. Side effects from use of NSAIDs are not uncommon and can affect almost every organ system in the body. NSAIDs are notorious for causing pulmonary toxicity, the common ones being bronchospasm and hypersensitivity reactions. Diffuse alveolar hemorrhage (DAH) secondary to NSAIDs is uncommon. Here, we report a case of DAH secondary to the use of ketorolac tromethamine.

  7. Imaging features of alveolar soft part sarcoma

    Institute of Scientific and Technical Information of China (English)

    Teng Jin; Ping Zhang Co-first author; Xiaoming Li

    2015-01-01

    Objective The aim of this study was to analyze the imaging features of alveolar soft part sarcoma (ASPS). Methods The imaging features of 11 cases with ASPS were retrospectively analyzed. Results ASPS mainly exhibited an isointense or slightly high signal intensity on T1-weighted imaging (T1WI), and a mixed high signal on T2-weighted imaging (T2WI). ASPS was partial, with rich tortuous flow voids, or “line-like” low signal septa. The essence of the mass was heterogeneous enhancement. The 1H-MRS showed a slight choline peak at 3.2 ppm. Conclusion The wel-circumscribed mass and blood voids, combined with “line-like” low signals play a significant role in diagnosis. The choline peak and the other signs may be auxiliary diagnoses.

  8. Vestibuloplasty after secondary alveolar bone grafting.

    Science.gov (United States)

    Iino, M; Fukuda, M; Murakami, K; Horiuchi, T; Niitsu, K; Seto, K

    2001-11-01

    This paper introduces a surgical technique for vestibuloplasty after secondary alveolar bone grafting of patients with cleft lip and palate (CLP). This paper also reports on the patients who underwent this modified vestibuloplasty. The vestibuloplasty technique described in this paper consists of: (1) reduction of submucosal scar tissue of the upper lip, (2) V-Y plasty of the superficial mucosa, (3) placement of horizontal mattress sutures between nostril floor skin and freed marginal mucosa, (4) application of artificial skin to cover the exposed periosteal surface, and (5) use of a removable retention splint. This surgical procedure appears to be very useful for patients with CLP. The technique enables the surgeon to obtain an adequate sulcus depth around the graft area. In addition, this technique releases the mucosal scar contraction and improves the shape and mobility of the upper lip.

  9. [Clinical aspect of diffuse alveolar hemorrhage syndrome].

    Science.gov (United States)

    Ishida, Kazuo; Seki, Reiko; Inoue, Takeo; Iwamoto, Tokuzen; Hoshino, Makoto; Nakagawa, Takemasa

    2003-12-01

    Thirteen cases of diffuse alveolar hemorrhage (DAH) were encountered in our Hospital between January 1996 and October 2001. Eight patients were men and five were women, their mean age being 59.5 +/- 19.2 years (range, 18-88 years). Three patients had systemic lupus erythematosus (SLE), three (23%) had polyarteritis nodosa (including microscopic PN), one (7.7%) had allergic granulomatous angitis, one (7.7%) had Goodpasture syndrome, one (7.7%) had MPO-ANCA-associated vasculitis, one (7.7%) had Behçet's disease, one (7.7%) had chronic heart failure caused by mitral stenosis, one (7.7%) had chronic renal failure (etiology unknown), and the last had no particular disorder. Nine episodes (69%) had occurred as complications of primary diseases, four (31%) as the first symptoms of underlying diseases. Prognosis was poor in the former cases but in the latter, the prognosis was relatively favorable.

  10. Fertility Preservation for Female

    Institute of Scientific and Technical Information of China (English)

    Jack Huang; Seang Lin Tan; Ri-Cheng Chian

    2006-01-01

    Preservation of female fertility is an important issue today. However, there are few effective clinical options for preserving female fertility. Firstly, conventional in vitro fertilization (IVF) followed by embryo cryopreservation is an accepted procedure but is not applicable to all women. Embryo freezing is suitable only for women with a male partner and may not be acceptable to some patients due to moral and religious reasons. Ovarian tissue freezing is another option of female fertility preservation but is an invasive procedure and the efficacy of this technique remains to be determined.Oocyte cryopreservation is also method for fertility preservation. Egg freezing is minimally invasive and can avoid the ethical and moral concerns related to cryopreservation of embryos. However, conventional slow freezing/rapid thawing methods are associated with low survival of oocytes. Recent development in vitrification of oocytes appears promising. Therefore, vitrification of unfertilized eggs may be a novel method to preserve female fertility.

  11. [Clinicopathological diagnosis of diffuse alveolar hemorrhage].

    Science.gov (United States)

    Fang, F; Li, Y M; Hu, S T; Wang, H T; Liu, D G; Wang, C

    2016-01-12

    To improve knowledge about the clinical and pathological features of diffuse alveolar hemorrhage (DAH). Six cases DAH with intact clinical and pathological data were retrospectively analyzed during the period from May 1999 to May 2015 in Beijing Hospital. There were altogether 2 males and 4 females, with age ranging from 32 to 68 years (mean 58.8 years). Specimens were obtained by autopsy (3 cases), open lung biopsy (2 cases) and renal biopsy (2 cases), including 1 case of open lung biopsy in 2003, renal biopsy in 2012. Clinically, the patients presented with cough, shortness of breath and dyspnea, including 5 cases of hemoptysis, 4 cases of fever, 3 cases of skin and mucosa bleeding, 2 cases of gross hematuria, 2 cases of microscopic hematuria, 3 cases of renal functional impairment. A total of 5 cases had different levels of elevated erythrocyte sedimentation rate and C-reactive protein, 6 cases had moderate anemia, hypoxemia, diffuse infiltrates with alveolar filling in chest CT. Serum antineutrophil cytoplasmic antibody was positive in 3 cases, anti-glomerular basement membrane antibody was present in 1 case. Pathological diagnosis: 2 cases of Granulomatosis with polyangiitis (GPA), 2 cases of Microscopic polyangiitis (MPA), 1 case of Goodpasture syndrome, 1 case of pulmonary veno-occlusive disease (PVOD). 3 cases died; 2 cases were discharged; 1 case received symptomatic treatment, follow-up after discharge. The mainly clinical characteristics of DAH are varied degree of dyspnea, anemia, hypoxemia, and extensive ground-glass opacification or consolidation in image, with or without haemoptysis; diffuse acute or chronic pulmonary hemorrhage in lung tissue is the main pathological feature.

  12. Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function.

    Science.gov (United States)

    Langer, Marybeth; Duggan, Elizabeth Stewart; Booth, John Leland; Patel, Vineet Indrajit; Zander, Ryan A; Silasi-Mansat, Robert; Ramani, Vijay; Veres, Tibor Zoltan; Prenzler, Frauke; Sewald, Katherina; Williams, Daniel M; Coggeshall, Kenneth Mark; Awasthi, Shanjana; Lupu, Florea; Burian, Dennis; Ballard, Jimmy Dale; Braun, Armin; Metcalf, Jordan Patrick

    2012-12-01

    The lung is the site of entry for Bacillus anthracis in inhalation anthrax, the deadliest form of the disease. Bacillus anthracis produces virulence toxins required for disease. Alveolar macrophages were considered the primary target of the Bacillus anthracis virulence factor lethal toxin because lethal toxin inhibits mouse macrophages through cleavage of MEK signaling pathway components, but we have reported that human alveolar macrophages are not a target of lethal toxin. Our current results suggest that, unlike human alveolar macrophages, the cells lining the respiratory units of the lung, alveolar epithelial cells, are a target of lethal toxin in humans. Alveolar epithelial cells expressed lethal toxin receptor protein, bound the protective antigen component of lethal toxin, and were subject to lethal-toxin-induced cleavage of multiple MEKs. These findings suggest that human alveolar epithelial cells are a target of Bacillus anthracis lethal toxin. Further, no reduction in alveolar epithelial cell viability was observed, but lethal toxin caused actin rearrangement and impaired desmosome formation, consistent with impaired barrier function as well as reduced surfactant production. Therefore, by compromising epithelial barrier function, lethal toxin may play a role in the pathogenesis of inhalation anthrax by facilitating the dissemination of Bacillus anthracis from the lung in early disease and promoting edema in late stages of the illness.

  13. Eskers in Ireland, analogs for sinuous ridges on Mars

    Science.gov (United States)

    Pellicer, Xavier; Bourke, Mary

    2014-05-01

    resolution images also show the presence of large boulders. Large glacial lakes in the Irish Midlands during ice withdrawal aided the outstanding preservation of these features. This permitted the cataloguing of 'pristine' morphologies and morphometries. Esker-like ridges identified on Mars are often located in low relief and depressions and show similar topographic conditions to those in Ireland. The ExoMars rover scheduled to be launched on the surface of Mars by 2018 carries the first space-borne GPR system (Wisdom) with the objective of characterizing the top 3 m of the Martian subsurface. Ground Penetrating Radar (GPR) surveys carried out on the Irish eskers and associated sediments depicted the landforms internal architecture and paleocurrent indicators. A throughout investigation of the Irish eskers as Mars analogs using remote sensing methods and GPR will contribute to the understanding of sinuous ridges on Mars.

  14. Self-preserving cosmetics.

    Science.gov (United States)

    Varvaresou, A; Papageorgiou, S; Tsirivas, E; Protopapa, E; Kintziou, H; Kefala, V; Demetzos, C

    2009-06-01

    Preservatives are added to products for two reasons: first, to prevent microbial spoilage and therefore to prolong the shelf life of the product; second, to protect the consumer from a potential infection. Although chemical preservatives prevent microbial growth, their safety is questioned by a growing segment of consumers. Therefore, there is a considerable interest in the development of preservative-free or self-preserving cosmetics. In these formulations traditional/chemical preservatives have been replaced by other cosmetic ingredients with antimicrobial properties that are not legislated as preservatives according to the Annex VI of the Commission Directive 76/768/EEC and the amending directives (2003/15/EC, 2007/17/EC and 2007/22/EC). 'Hurdle Technology', a technology that has been used for the control of product safety in the food industry since 1970s, has also been applied for the production of self-preserving cosmetics. 'Hurdle Technology' is a term used to describe the intelligent combination of different preservation factors or hurdles to deteriorate the growth of microorganisms. Adherence to current good manufacturing practice, appropriate packaging, careful choice of the form of the emulsion, low water activity and low or high pH values are significant variables for the control of microbial growth in cosmetic formulations. This paper describes the application of the basic principles of 'Hurdle Technology' in the production of self-preserving cosmetics. Multifunctional antimicrobial ingredients and plant-derived essential oils and extracts that are used as alternative or natural preservatives and are not listed in Annex VI of the Cosmetic Directive are also reported.

  15. Student Health Services at Orchard Ridge.

    Science.gov (United States)

    Nichols, Don D.

    This paper provides a synoptic review of student health services at the community college level while giving a more detailed description of the nature of health services at Orchard Ridge, a campus of Oakland Community College. The present College Health Service program provides for a part-time (24 hrs./wk.) nurse at Orchard Ridge. A variety of…

  16. Pulley Ridge Swath Bathymetry Grid - filtered

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Pulley Ridge is a series of drowned barrier islands that extends almost 200 km in 60-100 m water depths. This drowned ridge is located on the Florida Platform in...

  17. Pulley Ridge Swath Bathymetry Grid - filtered

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Pulley Ridge is a series of drowned barrier islands that extends almost 200 km in 60-100 m water depths. This drowned ridge is located on the Florida Platform in the...

  18. Pulley Ridge Swath Bathymetry Grid - filtered

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Pulley Ridge is a series of drowned barrier islands that extends almost 200 km in 60-100 m water depths. This drowned ridge is located on the Florida Platform in the...

  19. Petrology of tectonically segmented Central Indian Ridge

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R.; Iyer, S.D.

    Distribution and mineralogy of various rock types along the 4200-km-long slow-spreading Central Indian Ridge, between Owen fracture zone in the north and Indian Ocean triple junction in the south, is studied in the light of ridge segmentation...

  20. The Glasma and the Hard Ridge

    CERN Document Server

    Moschelli, George

    2009-01-01

    Correlation measurements indicate that excess two particle correlations extend over causally disconnected rapidity ranges. Although, this enhancement is broad in relative rapidity $\\eta=\\eta_1 - \\eta_2$, it is focused in a narrow region in relative azimuthal angle $\\phi=\\phi_1 - \\phi_2$. The resulting structure looks like a ridge centered at $\\eta = \\phi=0$. Similar ridge structures are observed in correlations of particles associated with a jet trigger (the hard ridge) and in correlations without a trigger (the soft ridge). The long range rapidity behavior requires that the correlation originates in the earliest stage of the collision, and probes properties of the production mechanism. Glasma initial conditions as predicted by the theory of Color Glass Condensate and provide a and early stage correlation that naturally extends far in rapidity. We have previously shown that the soft ridge is a consequence of particles forming from an initial Glasma phase that experience a later stage transverse flow. We exten...

  1. Fractura da cortical alveolar resultante da exodontia de dentes anquilosados

    OpenAIRE

    2010-01-01

    Monografia apresentada à Universidade Fernando Pessoa para obtenção do grau Licenciado em Medicina Dentária A anquilose dento-alveolar constitui uma condição patológica que consiste na fusão anatómica entre o cemento radicular e o osso alveolar propriamente dito, podendo ocorrer durante qualquer etapa do processo eruptivo. Os factores etiológicos da anquilose dento-alveolar ainda não estão totalmente esclarecidos, existindo diversas teorias que pretendem explicar o fenómeno. O objectivo...

  2. The influence of root surface distance to alveolar bone and periodontal ligament on periodontal wound healing

    Science.gov (United States)

    2016-01-01

    Purpose The purpose of this animal study was to perform a 3-dimensional micro-computed tomography (micro-CT) analysis in order to investigate the influence of root surface distance to the alveolar bone and the periodontal ligament on periodontal wound healing after a guided tissue regeneration (GTR) procedure. Methods Three adult Sus scrofa domesticus specimens were used. The study sample included 6 teeth, corresponding to 2 third mandibular incisors from each animal. After coronectomy, a circumferential bone defect was created in each tooth by means of calibrated piezoelectric inserts. The experimental defects had depths of 3 mm, 5 mm, 7 mm, 9 mm, and 11 mm, with a constant width of 2 mm. One tooth with no defect was used as a control. The defects were covered with a bioresorbable membrane and protected with a flap. After 6 months, the animals were euthanised and tissue blocks were harvested and preserved for micro-CT analysis. Results New alveolar bone was consistently present in all experimental defects. Signs of root resorption were observed in all samples, with the extent of resorption directly correlated to the vertical extent of the defect; the medial third of the root was the most commonly affected area. Signs of ankylosis were recorded in the defects that were 3 mm and 7 mm in depth. Density and other indicators of bone quality decreased with increasing defect depth. Conclusions After a GTR procedure, the periodontal ligament and the alveolar bone appeared to compete in periodontal wound healing. Moreover, the observed decrease in bone quality indicators suggests that intrabony defects beyond a critical size cannot be regenerated. This finding may be relevant for the clinical application of periodontal regeneration, since it implies that GTR has a dimensional limit. PMID:27800213

  3. Chronopolis Digital Preservation Network

    Directory of Open Access Journals (Sweden)

    David Minor

    2010-07-01

    Full Text Available The Chronopolis Digital Preservation Initiative, one of the Library of Congress’ latest efforts to collect and preserve at-risk digital information, has completed its first year of service as a multi-member partnership to meet the archival needs of a wide range of domains.Chronopolis is a digital preservation data grid framework developed by the San Diego Supercomputer Center (SDSC at UC San Diego, the UC San Diego Libraries (UCSDL, and their partners at the National Center for Atmospheric Research (NCAR in Colorado and the University of Maryland's Institute for Advanced Computer Studies (UMIACS.Chronopolis addresses a critical problem by providing a comprehensive model for the cyberinfrastructure of collection management, in which preserved intellectual capital is easily accessible, and research results, education material, and new knowledge can be incorporated smoothly over the long term. Integrating digital library, data grid, and persistent archive technologies, Chronopolis has created trusted environments that span academic institutions and research projects, with the goal of long-term digital preservation.A key goal of the Chronopolis project is to provide cross-domain collection sharing for long-term preservation. Using existing high-speed educational and research networks and mass-scale storage infrastructure investments, the partnership is leveraging the data storage capabilities at SDSC, NCAR, and UMIACS to provide a preservation data grid that emphasizes heterogeneous and highly redundant data storage systems.In this paper we will explore the major themes within Chronopolis, including:a The philosophy and theory behind a nationally federated data grid for preservation. b The core tools and technologies used in Chronopolis. c The metadata schema that is being developed within Chronopolis for all of the data elements. d Lessons learned from the first year of the project.e Next steps in digital preservation using Chronopolis: how we

  4. Abandoned Beach Ridges in the Mejillones Peninsula, Northern Chile: Implications for Paleoseismology of Great Subduction Earthquakes.

    Science.gov (United States)

    del Río, I. A.; Gonzalez, G.; Antinao, J. L.; McDonald, E.; González-Carrasco, J. F.; Shrivastava, M. N.

    2015-12-01

    The Mejillones Peninsula, in northern Chile, shows a well-preserved set of beach ridges parallel to the present coast. These beach ridges can be observed up to 20 km inland and at 200 m above sea level. Previous dating performed in fossils extracted from the oldest beach ridges yielded ages of 400 ka (Victor et al., 2011). However, numerical ages for younger beach ridges have not been determined, therefore a complete time record is not available. InSar data show that the Mejillones Peninsula was uplifted several centimeters during the last two subduction earthquakes (Antofagasta Mw 8.1, 1995 earthquake and the Mw 7.7, 2007 Tocopilla earthquake) occurred in the area (Loveless et al., 2010). A permanent GPS station deployed by CALTECH (http://web.gps.caltech.edu/~jeff/andes/) in this peninsula has measured a coseismic uplift during the 2007 Tocopilla earthquake. This data suggest that the beach ridges were abandoned as a consequence of coseismic uplift during great subduction earthquakes and therefore they represent the long-term record of past earthquakes. In order to prove this hypothesis we excavated five trenches across the beach ridges. Our idea is to look for stratigraphic evidence of the abandonment mechanism and to collect samples for dating the beach ridges using the method of optically stimulated luminescence (OSL). The ages will be used to estimate long-term uplift rate and temporal variation of this rate. By confronting short-term uplift rate provided by GPS data with long-term rate we hope to know what it is the amount of the coseismic slip that remain in the geological record.

  5. Autoimmune pulmonary alveolar proteinosis co-existing with breast cancer: a case report

    OpenAIRE

    Sawai, Toyomitsu; Umeyama, Yasuhiro; Yoshioka, Sumako; Matsuo, Nobuko; Suyama, Naofumi; Kohno, Shigeru

    2014-01-01

    Introduction. Pulmonary alveolar proteinosis is a rare pulmonary disease characterized by excessive alveolar accumulation of surfactant due to defective alveolar clearance by macrophages. There are only a few published case reports of pulmonary alveolar proteinosis occurring in association with solid cancers. To the best of our knowledge, there are no previously reported cases of pulmonary alveolar proteinosis associated with breast cancer. Case presentation. A 48-year-old Asian woman, a nons...

  6. Prevention of Alveolar Osteitis After Third Molar Surgery ...

    African Journals Online (AJOL)

    2017-05-16

    May 16, 2017 ... of alveolar osteitis after third molar surgery: Comparative study of the effect of warm saline ... recovery after dental extractions as evidenced by reports across the ... routine use after oral surgical procedures not to be common.

  7. Alveolar cleft closure with iliac bone graft: A case report.

    Directory of Open Access Journals (Sweden)

    Tichvy Tammama

    2017-04-01

    Conclusion: The timing of alveolar bone grafting usually associated with the state of the developing of dentition. Post operative management is important to get a good result, and to prevent any complications.

  8. Alveolar proteinosis in Behçet's disease

    Directory of Open Access Journals (Sweden)

    Tetikkurt Cuneyt

    2010-08-01

    Full Text Available Abstract A 51-year-old man with Behçet's disease complained of fever, dry cough and dyspnea during exertion. Chest CT showed ground glass opacities with interstitial septal thickening in both lungs. Bronchoalveolar lavage (BAL revealed amorphous and lipoproteinaceous material that was periodic acid-Schiff (PAS stain positive. Transbronchial biopsy specimen demonstrated PAS positive alveolar eosinophilic material consistent with pulmonary alveolar proteinosis. Serum anti-granulocyte-macrophage colony stimulating factor (GM-CSF antibody was negative. Recent studies have reported anti-GMCSF not present in the the serum of patients with secondary pulmonary alveolar proteinosis (PAP but they have not reported so in patients with idiopathic PAP. We report a case of alveolar proteinosis in the setting of Behçet's disease with spontaneous remission.

  9. The role of synthetic biomaterials in resorptive alveolar bone regeneration

    Directory of Open Access Journals (Sweden)

    Kaličanin Biljana M.

    2007-01-01

    Full Text Available The alveolar bone tissue resorption defect has a significant role in dentistry. Because of the bone tissue deficit developed by alveolar resorption, the use of synthetic material CP/PLGA (calcium-phosphate/polylactide-co-gliycolide composite was introduced. Investigations were performed on rats with artificially produced resorption of the mandibular bone. The results show that the best effect on alveolar bone were attained by using nano-composite implants. The effect of the nanocomposite was ascertained by determining the calcium and phosphate content, as a basis of the hydroxyapatite structure. The results show that synthetic CP/PLGA nanocomposite alleviate the rehabilitation of weakened alveolar bone. Due to its osteoconductive effect, CP/PLGA can be the material of choice for bone substitution in the future.

  10. VT Historic Preservation Grant

    Data.gov (United States)

    Vermont Center for Geographic Information — The State-funded Historic Preservation Grant Program helps municipalities and non-profit organizations rehabilitate the historic buildings that are a vital part of...

  11. Global ridge orientation modeling for partial fingerprint identification.

    Science.gov (United States)

    Wang, Yi Alice; Hu, Jiankun

    2011-01-01

    Identifying incomplete or partial fingerprints from a large fingerprint database remains a difficult challenge today. Existing studies on partial fingerprints focus on one-to-one matching using local ridge details. In this paper, we investigate the problem of retrieving candidate lists for matching partial fingerprints by exploiting global topological features. Specifically, we propose an analytical approach for reconstructing the global topology representation from a partial fingerprint. First, we present an inverse orientation model for describing the reconstruction problem. Then, we provide a general expression for all valid solutions to the inverse model. This allows us to preserve data fidelity in the existing segments while exploring missing structures in the unknown parts. We have further developed algorithms for estimating the missing orientation structures based on some a priori knowledge of ridge topology features. Our statistical experiments show that our proposed model-based approach can effectively reduce the number of candidates for pair-wised fingerprint matching, and thus significantly improve the system retrieval performance for partial fingerprint identification.

  12. Digital preservation for heritages

    CERN Document Server

    Lu, Dongming

    2011-01-01

    ""Digital Preservation for Heritages: Technologies and Applications"" provides a comprehensive and up-to-date coverage of digital technologies in the area of cultural heritage preservation, including digitalization, research aiding, conservation aiding, digital exhibition, and digital utilization. Processes, technical frameworks, key technologies, as well as typical systems and applications are discussed in the book. It is intended for researchers and students in the fields of computer science and technology, museology, and archaeology. Dr. Dongming Lu is a professor at College of Computer Sci

  13. Alveolar lymphangioma in infants: report of two cases.

    LENUS (Irish Health Repository)

    FitzGerald, Kirsten

    2009-06-01

    The alveolar lymphangioma is a benign but relatively rare condition found only in the oral cavities of black infants. Dentists practising in Ireland may be unaware of this condition due to its racial specificity. This paper presents two case reports of multiple alveolar lymphangiomas found in black infants in a children\\'s hospital in Ireland. The epidemiology, aetiology, clinical presentation, histology, and management options are discussed. The photographs should aid the practitioner in recognising these lesions.

  14. Impact of the Oral Commensal Flora on Alveolar Bone Homeostasis

    OpenAIRE

    Irie, K; Novince, C.M.; Darveau, R. P.

    2014-01-01

    Homeostasis of healthy periodontal tissues is affected by innate and adaptive immunosurveillance mechanisms in response to the normal oral flora. Recent comparisons of germ-free (GF) and normal specific-pathogen-free (SPF) mice have revealed the impact of host immunosurveillance mechanisms in response to the normal oral flora on alveolar bone height. Prior reports that alveolar bone height is significantly less in normal SPF mice compared with their age- and strain-matched GF counterparts sug...

  15. Modified Dento - Alveolar Distraction Osteogenesis Technique for Rapid Canine Retraction

    Directory of Open Access Journals (Sweden)

    Sameer Patil

    2012-01-01

    Full Text Available Distraction Osteogenesis claims to reduce the duration of treatment as well aid in conservation of anchorage. With the introduction of Dento- alveolar distraction retraction of canine can now be done in about 2-3 weeks with minimal loss of anchorage and little/no root resorption. However, surgical procedure required for dento-alveolar distraction can cause significant swelling and post operative discomfort. Our small modification in the surgical procedure drastically reduces the discomfort and improves patient compliance.

  16. Modified Dento - Alveolar Distraction Osteogenesis Technique for Rapid Canine Retraction

    OpenAIRE

    Sameer Patil; Sharadindu Kotrashetti; Sumit Yadev; Ketan Vhora

    2012-01-01

    Distraction Osteogenesis claims to reduce the duration of treatment as well aid in conservation of anchorage. With the introduction of Dento- alveolar distraction retraction of canine can now be done in about 2-3 weeks with minimal loss of anchorage and little/no root resorption. However, surgical procedure required for dento-alveolar distraction can cause significant swelling and post operative discomfort. Our small modification in the surgical procedure drastically reduces the discomfort an...

  17. Alveolar lymphangioma in infants: report of two cases.

    LENUS (Irish Health Repository)

    FitzGerald, Kirsten

    2012-02-01

    The alveolar lymphangioma is a benign but relatively rare condition found only in the oral cavities of black infants. Dentists practising in Ireland may be unaware of this condition due to its racial specificity. This paper presents two case reports of multiple alveolar lymphangiomas found in black infants in a children\\'s hospital in Ireland. The epidemiology, aetiology, clinical presentation, histology, and management options are discussed. The photographs should aid the practitioner in recognising these lesions.

  18. Dynamic thermal performance of alveolar brick construction system

    Energy Technology Data Exchange (ETDEWEB)

    Gracia, A. de; Castell, A.; Medrano, M. [GREA Innovacio Concurrent, Edifici CREA, Universitat de Lleida, Pere de Cabrera s/n, 25001 Lleida (Spain); Cabeza, L.F., E-mail: lcabeza@diei.udl.ca [GREA Innovacio Concurrent, Edifici CREA, Universitat de Lleida, Pere de Cabrera s/n, 25001 Lleida (Spain)

    2011-07-15

    Highlights: {yields} Even though U-value does not measure thermal inertia, it is the commonly used parameter. {yields} The thermal performance analysis of buildings must include the evaluation of transient parameters. {yields} Transient parameters of alveolar brick constructive system show good agreement with its low energy consumption. -- Abstract: Alveolar bricks are being introduced in building sector due to the simplicity of their construction system and to the elimination of the insulation material. Nevertheless, it is not clear if this new system is energetically efficient and which is its thermal behaviour. This paper presents an experimental and theoretical study to evaluate the thermal behaviour of the alveolar brick construction system, compared with a traditional Mediterranean brick system with insulation. The experimental study consists of measuring the thermal performance of four real house-like cubicles. The thermal transmittance in steady-state, also known as U-value, is calculated theoretically and experimentally for each cubicle, presenting the insulated cubicles as the best construction system, with differences around 45% in comparison to the alveolar one. On the other hand, experimental results show significantly smaller differences on the energy consumption between the alveolar and insulated construction systems during summer period (around 13% higher for the alveolar cubicle). These values demonstrate the high thermal efficiency of the alveolar system. In addition, the lack of agreement between the measured energy consumption and the calculated U-values, guides the authors to analyze the thermal inertia of the different building components. Therefore, several transient parameters, extracted from the heat transfer matrix and from experimental data, are also evaluated. It can be concluded that the alveolar brick construction system presents higher thermal inertia than the insulated one, justifying the low measured energy consumption.

  19. Neutrophil-induced injury of rat pulmonary alveolar epithelial cells.

    OpenAIRE

    Simon, R H; DeHart, P D; Todd, R F

    1986-01-01

    The damage to pulmonary alveolar epithelial cells that occurs in many inflammatory conditions is thought to be caused in part by phagocytic neutrophils. To investigate this process, we exposed monolayers of purified rat alveolar epithelial cells to stimulated human neutrophils and measured cytotoxicity using a 51Cr-release assay. We found that stimulated neutrophils killed epithelial cells by a process that did not require neutrophil-generated reactive oxygen metabolites. Pretreatment of neut...

  20. Anaesthetic management of bilateral alveolar proteinosis for bronchopulmonary lavage.

    Directory of Open Access Journals (Sweden)

    Dixit R

    1998-01-01

    Full Text Available The most hazardous manifestation of pulmonary alveolar proteinosis is progressive hypoxia for which bronchopulmonary lavage (BPL is the single most effective treatment. Unfortunately this procedure under general anesthesia itself increases the risk of hypoxia due to the need for one lung ventilation. It was therefore considered interesting to report the successful anaesthetic management of a patient with pulmonary alveolar proteinosis for Bronchopulmonary lavage.

  1. Horizontal alveolar bone loss: A periodontal orphan

    Directory of Open Access Journals (Sweden)

    Jayakumar A

    2010-01-01

    Full Text Available Background: Attempts to successfully regenerate lost alveolar bone have always been a clinician′s dream. Angular defects, at least, have a fairer chance, but the same cannot be said about horizontal bone loss. The purpose of the present study was to evaluate the prevalence of horizontal alveolar bone loss and vertical bone defects in periodontal patients; and later, to correlate it with the treatment modalities available in the literature for horizontal and vertical bone defects. Materials and Methods: The study was conducted in two parts. Part I was the radiographic evaluation of 150 orthopantomographs (OPGs (of patients diagnosed with chronic periodontitis and seeking periodontal care, which were digitized and read using the AutoCAD 2006 software. All the periodontitis-affected teeth were categorized as teeth with vertical defects (if the defect angle was ≤45° and defect depth was ≥3 mm or as having horizontal bone loss. Part II of the study comprised search of the literature on treatment modalities for horizontal and vertical bone loss in four selected periodontal journals. Results: Out of the 150 OPGs studied, 54 (36% OPGs showed one or more vertical defects. Totally, 3,371 teeth were studied, out of which horizontal bone loss was found in 3,107 (92.2% teeth, and vertical defects were found only in 264 (7.8% of the teeth, which was statistically significant (P<.001. Search of the selected journals revealed 477 papers have addressed the treatment modalities for vertical and horizontal types of bone loss specifically. Out of the 477 papers, 461 (96.3% have addressed vertical bone loss, and 18 (3.7% have addressed treatment options for horizontal bone loss. Two papers have addressed both types of bone loss and are included in both categories. Conclusion: Horizontal bone loss is more prevalent than vertical bone loss but has been sidelined by researchers as very few papers have been published on the subject of regenerative treatment

  2. SRTM Anaglyph: Wheeler Ridge, California

    Science.gov (United States)

    2000-01-01

    Wheeler Ridge and vicinity, California, is a site of major tectonic activity, both historically and over recent geologic time. The epicenter of the 7.5 magnitude Kern County earthquake occurred here on July 21,1952, and numerous geologic and topographic features indicate rapid geologic processes. The ridge itself (upper-right center) is a geologic fold that is growing out of the southern San Joaquin Valley. A prominent 'wind gap,' now used for passage of the California aquaduct (with the aid of a pumping station), is evidence that the ridge grew faster than tranversing streams could erode down. Nearby abrupt and/or landslid mountain fronts similarly indicate a vigorous tectonic setting here, just north of the San Andreas fault. The Interstate 5 freeway can be seen crossing agricultural fields on the right and entering the very rugged and steep Grapevine Canyon toward the bottom.This anaglyph was generated by first draping a Landsat satellite image over a preliminary topographic map from the Shuttle Radar Topography Mission (SRTM), then generating two differing perspectives, one for each eye. When viewed through special glasses, the result is a vertically exaggerated view of the Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter. Landsat has been providing visible and infrared views of the Earth since 1972. SRTM elevation data matches the 30 meter resolution of most Landsat images and will substantially help in analyses of the large and growing Landsat image archive.The elevation data used in this image was acquired by SRTM aboard the Space Shuttle Endeavour, launched on February 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data

  3. Planktic foraminifer census data from Northwind Ridge cores PI-88-AP P3, PI-88-AR P7 and PI-88-AR P9, Arctic Ocean

    Science.gov (United States)

    Foley, Kevin M.; Poore, Richard Z.

    1993-01-01

    The U.S. Geological Survey recovered 9 piston cores from the Northwind Ridge in the Canada Basin of the Arctic Ocean from a cruise of the USCGC Polar Star during 1988. Preliminary analysis of the cores suggests sediments deposited on Northwind Ridge preserve a detailed record of glacial and interglacial cycles for the last few hundred-thousand to one million years. This report includes quantitative data on foraminifers and selected sediment size-fraction data in 98 samples from Northwind Ridge core PI-88AR P3, 51 samples from core PI-88-AR P7 and 117 samples from core PI-88-AR P9.

  4. Anterior Ridge Extension Using Modified Kazanjian Technique in Mandible- A Clinical Study

    Science.gov (United States)

    Kumar, Jagannadham Vijay; Chakravarthi, Pandi Srinivas; Sridhar, Meka; Devi, Kolli Naga Neelima; Lingamaneni, Krishna Prasad

    2016-01-01

    Introduction Good alveolar ridge is a prerequisite for successful conventional/ implant supported partial/complete denture. Extensively resorbed ridges with shallow vestibule and high insertion of muscles in to the ridge crest, leads to failure of prosthesis. Success of prosthesis depends on surgical repositioning of mucosa and muscle insertions, which increases the depth of vestibule and denture flange area for retention. So, the study was planned to provide good attached gingiva with adequate vestibular depth using Modified Kazanjian Vestibuloplasty (MKV). Aim To evaluate efficacy of MKV technique for increasing vestibular depth in anterior mandible so that successful prosthesis can be delivered. Efficacy of the technique was evaluated through operating time required, vestibular depth achieved, scarring or relapse and any postoperative complications associated with the healing. Materials and Methods Total of 10 patients were included in the study, who had minimum 20mm of bone height and less than 5mm of vestibular depth for MKV procedure. The results were tabulated and statistical analysis was carried out to assess vestibular depth achieved i.e. from crest of the ridge to junction of attached mucosa both pre and postoperatively. The study results were compared with existing literature. Results Healing of raw surface was uneventful with satisfactory achievement of vestibular depth. The average gain in vestibular depth was 11 mm. The patients had good satisfaction index for prosthesis. Conclusion Even in the era of implant prosthesis Modified Kazanjian technique is worth to practice to achieve good results and overcorrection is not required as that of standard Kazanjian technique. It provides adequate attached gingiva for successful prosthesis. Extension of vestibular depth enables fabrication of better denture flange with improved oral hygiene. This technique does not require hospitalization and additional surgery for grafts. PMID:27042579

  5. Bayesian inference of the lung alveolar spatial model for the identification of alveolar mechanics associated with acute respiratory distress syndrome

    Science.gov (United States)

    Christley, Scott; Emr, Bryanna; Ghosh, Auyon; Satalin, Josh; Gatto, Louis; Vodovotz, Yoram; Nieman, Gary F.; An, Gary

    2013-06-01

    Acute respiratory distress syndrome (ARDS) is acute lung failure secondary to severe systemic inflammation, resulting in a derangement of alveolar mechanics (i.e. the dynamic change in alveolar size and shape during tidal ventilation), leading to alveolar instability that can cause further damage to the pulmonary parenchyma. Mechanical ventilation is a mainstay in the treatment of ARDS, but may induce mechano-physical stresses on unstable alveoli, which can paradoxically propagate the cellular and molecular processes exacerbating ARDS pathology. This phenomenon is called ventilator induced lung injury (VILI), and plays a significant role in morbidity and mortality associated with ARDS. In order to identify optimal ventilation strategies to limit VILI and treat ARDS, it is necessary to understand the complex interplay between biological and physical mechanisms of VILI, first at the alveolar level, and then in aggregate at the whole-lung level. Since there is no current consensus about the underlying dynamics of alveolar mechanics, as an initial step we investigate the ventilatory dynamics of an alveolar sac (AS) with the lung alveolar spatial model (LASM), a 3D spatial biomechanical representation of the AS and its interaction with airflow pressure and the surface tension effects of pulmonary surfactant. We use the LASM to identify the mechanical ramifications of alveolar dynamics associated with ARDS. Using graphical processing unit parallel algorithms, we perform Bayesian inference on the model parameters using experimental data from rat lung under control and Tween-induced ARDS conditions. Our results provide two plausible models that recapitulate two fundamental hypotheses about volume change at the alveolar level: (1) increase in alveolar size through isotropic volume change, or (2) minimal change in AS radius with primary expansion of the mouth of the AS, with the implication that the majority of change in lung volume during the respiratory cycle occurs in the

  6. Historic Preservation Information CFM Website

    Data.gov (United States)

    Department of Veterans Affairs — The VA Historic Preservation Office keeps information about VA's programs to comply with Federal preservation requirements, and also interesting information about VA...

  7. Food Preservation beyond the Season.

    Science.gov (United States)

    Hanes, Phyllis

    1992-01-01

    Examines how current scientific knowledge of food preservation emerged from traditions handed down through the generations. Discusses various methods of preservation, their history, and current application. (LZ)

  8. Lung vasculitis and alveolar hemorrhage: pathology.

    Science.gov (United States)

    Fishbein, Gregory A; Fishbein, Michael C

    2011-06-01

    Pulmonary vasculitides are a diverse group of limited and systemic disorders associated with inflammation of pulmonary vessels and parenchyma. These diseases often have distinctive clinical, serological, and histopathological features-extrapulmonary sites of involvement, circulating autoantibodies, predispositions for small or large vessels, and others. Some have characteristic inflammatory lesions; others are characterized by the absence of such lesions. Frequently pathological findings overlap, rendering classification, and diagnosis a challenge. The anti-neutrophil cytoplasmic antibody (ANCA)-associated small-vessel diseases constitute the major pulmonary vasculitides. These include Wegener granulomatosis (WG), Churg Strauss syndrome (CSS), and microscopic polyangiitis (MPA). Less frequently, diseases such as polyarteritis nodosa, Takayasu arteritis, Behçet syndrome, and connective tissue diseases may involve pulmonary vessels, but these entities are better associated with extrapulmonary disease. Diffuse alveolar hemorrhage (DAH) is a severe manifestation of pulmonary vasculitis. DAH is most commonly seen in small-vessel vasculitides, specifically MPA and WG. Other syndromes associated with DAH include Goodpasture syndrome, Henoch-Schönlein purpura, and systemic lupus erythematosus. Less commonly, DAH may be secondary to infection or drugs/toxins. Furthermore, in the absence of discernable systemic disease, DAH may be idiopathic-referred to as isolated pulmonary capillaritis (IPC) or idiopathic pulmonary hemosiderosis (IPH), depending on the presence of capillaritis.

  9. An archaeological reconnaissance and evaluation of the Oak Ridge National Laboratory, Oak Ridge Reservation, Anderson and Roane Counties, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    DuVall, G.D.

    1994-01-01

    At the request of Martin Marietta Energy Systems, Inc., Oak Ridge, Tennessee, an archaeological reconnaissance and evaluation of the Oak Ridge National Laboratory (ORNL) developed areas was conducted between June I and September 2, 1993. The project was conducted by Glyn D. DuVall, Principal Investigator. ORNL project representative, Peter Souza, accompanied the principal investigator during all project evaluations. The reconnaissance to assess adverse impacts to cultural resources located within the boundaries of federally licensed, permitted, funded or assisted projects was conducted in compliance with the National Historic Preservation Act of 1966 (Public Law 89-665; 16 USC 470; 80 Stat. 915), National Environmental Policy Act of 1969 (Public Law 91-190; 91 Stat. 852; 42 USC 4321-4347) and Executive Order 11593 (May 13, 1971). Based upon the reconnaissance, a search of the site files at the Tennessee Division of Archaeology and a search of the National Register of Historic Places, the proposed construction on the site will have no impact on any property included in or eligible for inclusion in the National Register of Historic Places pursuant to 36 CFR 60.4. This judgement is based on the amount of prior disturbance associated with ORNL during the past 50 years. Construction in the vicinity of the New Bethel Baptist Church and Cemetery should allow sufficient buffer to avoid direct and visual impact to the property. The determination of sufficient buffer area, either distance or vegetative, should be coordinated with the Tennessee Historical Commission, Office of the State Historic Preservation Officer.

  10. Preserved history of global mean spreading rate: 83 Ma to present

    Science.gov (United States)

    Rowan, Christopher J.; Rowley, David B.

    2017-02-01

    Using an up-to-date global plate rotation model, applied to the endpoints of preserved major spreading ridge isochrons, we have calculated the explicitly reconstructable length-weighted mean global half-spreading rate (HSR), ridge length and area production as a function of time since the end of the Cretaceous Normal Superchron at 83.0 Ma. Our calculations integrate uncertainties in rotation parameters and chron boundary ages with the partial sampling uncertainties arising from progressive subduction of older oceanic lithosphere and its preserved spreading record. This record of directly reconstructable oceanic ridge production provides a well-constrained baseline that can be compared to reconstructions that include the largely unconstrained extrapolated histories of entirely subducted oceanic plates. The directly reconstructable global mean HSR has not varied by more than ±15 per cent about an average rate of 28.4 ± 4.6 mm a-1 since 83 Ma. No long-term secular trend is evident: a maximum global mean half-rate of 32 ± 6 mm a-1 occurred from 33.1 Ma to about 25.8 Ma, with minima of 26 ± 5 mm a-1 between about 56 and 40.2 Ma, and 24 ± 1 mm a-1 since 3.2 Ma. Only this most recent interval has a rate that differs significantly (at ±2σ) from the long-term mean. The global, reconstructable ridge length at 56 Ma decreases by less than 15 per cent relative to the modern ridge system; by 83 Ma it has decreased by 38 per cent. These relatively high preserved ridge fractions mean that the estimated uncertainty due to partial sampling stays roughly equivalent to the estimated rotation model uncertainties, allowing long-term spreading rate variations of >20 per cent since the Late Cretaceous to be ruled out. In contrast, prior to 83 Ma too little oceanic lithosphere is preserved to reliably reconstruct global spreading rates.

  11. Modeling Alveolar Epithelial Cell Behavior In Spatially Designed Hydrogel Microenvironments

    Science.gov (United States)

    Lewis, Katherine Jean Reeder

    The alveolar epithelium consists of two cell phenotypes, elongated alveolar type I cells (AT1) and rounded alveolar type II cells (ATII), and exists in a complex three-dimensional environment as a polarized cell layer attached to a thin basement membrane and enclosing a roughly spherical lumen. Closely surrounding the alveolar cysts are capillary endothelial cells as well as interstitial pulmonary fibroblasts. Many factors are thought to influence alveolar epithelial cell differentiation during lung development and wound repair, including physical and biochemical signals from the extracellular matrix (ECM), and paracrine signals from the surrounding mesenchyme. In particular, disrupted signaling between the alveolar epithelium and local fibroblasts has been implicated in the progression of several pulmonary diseases. However, given the complexity of alveolar tissue architecture and the multitude of signaling pathways involved, designing appropriate experimental platforms for this biological system has been difficult. In order to isolate key factors regulating cellular behavior, the researcher ideally should have control over biophysical properties of the ECM, as well as the ability to organize multiple cell types within the scaffold. This thesis aimed to develop a 3D synthetic hydrogel platform to control alveolar epithelial cyst formation, which could then be used to explore how extracellular cues influence cell behavior in a tissue-relevant cellular arrangement. To accomplish this, a poly(ethylene glycol) (PEG) hydrogel network containing enzymatically-degradable crosslinks and bioadhesive pendant peptides was employed as a base material for encapsulating primary alveolar epithelial cells. First, an array of microwells of various cross-sectional shapes was photopatterned into a PEG gel containing photo-labile crosslinks, and primary ATII cells were seeded into the wells to examine the role of geometric confinement on differentiation and multicellular arrangement

  12. KINERJA JACKKNIFE RIDGE REGRESSION DALAM MENGATASI MULTIKOLINEARITAS

    Directory of Open Access Journals (Sweden)

    HANY DEVITA

    2015-02-01

    Full Text Available Ordinary least square is a parameter estimations for minimizing residual sum of squares. If the multicollinearity was found in the data, unbias estimator with minimum variance could not be reached. Multicollinearity is a linear correlation between independent variabels in model. Jackknife Ridge Regression(JRR as an extension of Generalized Ridge Regression (GRR for solving multicollinearity.  Generalized Ridge Regression is used to overcome the bias of estimators caused of presents multicollinearity by adding different bias parameter for each independent variabel in least square equation after transforming the data into an orthoghonal form. Beside that, JRR can  reduce the bias of the ridge estimator. The result showed that JRR model out performs GRR model.

  13. Training for Preservation Management

    Directory of Open Access Journals (Sweden)

    Mirjam M. Foot

    1999-05-01

    Full Text Available In August 1997 the first of a series of summer schools in Preservation Management was held at the Archivschule in Marburg (Germany. The school was organised by the ECPA, the LIBER Division on Preservation, ICA and the Archivschule itself and was aimed at archivists and librarians in management positions from European institutions. It dealt with managerial, organisational and financial aspects of preservation and required active participation by those attending. Apart from introductory sessions by the teaching staff at the Archivschule, a large part of the course took the form of working groups, discussions, assignments and role play, to which participants were expected to take their own experience and problems. The school was conducted in German. Topics, spread over five days, ranged from preservation in the context of the core activities of libraries and archives; planning of preservation projects; general management issues, such as resource management, budgeting, priority setting, communication and effecting change; to more detailed considerations of day-to-day issues, such as storage, disaster control, microfilming and digitising, mass conservation processes, and moulds and fungi.

  14. Oak Ridge TNS Program: system description manual

    Energy Technology Data Exchange (ETDEWEB)

    Reid, R.L.; Becraft, W.R.; Brown, T.G.; Peng, Y.K.M.; Sardella, C.; Shannon, T.E.; Steiner, D.; Wells, W.M.; Wiseman, G.W.

    1979-05-01

    This document provides a systems description of the Reference Design for The Next Step (TNS) evolved at Oak Ridge National Laboratory (ORNL) during FY 1978. The description is presented on the basis of 24 individual device and facility systems. Additional information on these systems, the Reference Design, and the FY 1978 Oak Ridge TNS activities can be found in the associated technical memoranda, ORNL/TM-6720 and ORNL/TM-6722--ORNL/TM-6733.

  15. Realization of Ridge Regression in MATLAB

    Science.gov (United States)

    Dimitrov, S.; Kovacheva, S.; Prodanova, K.

    2008-10-01

    The least square estimator (LSE) of the coefficients in the classical linear regression models is unbiased. In the case of multicollinearity of the vectors of design matrix, LSE has very big variance, i.e., the estimator is unstable. A more stable estimator (but biased) can be constructed using ridge-estimator (RE). In this paper the basic methods of obtaining of Ridge-estimators and numerical procedures of its realization in MATLAB are considered. An application to Pharmacokinetics problem is considered.

  16. Oak Ridge Reservation environmental report for 1989

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, V.A.; Wilson, A.R. (eds.)

    1990-10-01

    This two-volume report, the Oak Ridge Reservation Environmental Report for 1989, is the nineteenth in an annual series that began in 1971. It reports the results of a comprehensive, year-round program to monitor the impact of operations at the three major US Department of Energy (DOE) production and research installations in Oak Ridge on the immediate areas' and surrounding region's groundwater and surface waters, soil, air quality, vegetation and wildlife, and through these multiple and varied pathways, the resident human population. Information is presented for the environmental monitoring Quality Assurance (QA) Program, audits and reviews, waste management activities, land special environmental studies. Data are included for the Oak Ridge Y-12 Plant, Oak Ridge National Laboratory (ORNL), and Oak Ridge Gaseous Diffusion Plant (ORGDP). Volume 1 presents narratives, summaries, and conclusions based on environmental monitoring at the three DOE installations and in the surrounding environs during calendar year (CY) 1989. Volume 1 is intended to be a stand-alone'' report about the Oak Ridge Reservation (ORR) for the reader who does not want an in-depth review of 1989 data. Volume 2 presents the detailed data from which these conclusions have been drawn and should be used in conjunction with Volume 1.

  17. Assessing the clarity of friction ridge impressions.

    Science.gov (United States)

    Hicklin, R Austin; Buscaglia, JoAnn; Roberts, Maria Antonia

    2013-03-10

    The ability of friction ridge examiners to correctly discern and make use of the ridges and associated features in finger or palm impressions is limited by clarity. The clarity of an impression relates to the examiner's confidence that the presence, absence, and attributes of features can be correctly discerned. Despite the importance of clarity in the examination process, there have not previously been standard methods for assessing clarity in friction ridge impressions. We introduce a process for annotation, analysis, and interchange of friction ridge clarity information that can be applied to latent or exemplar impressions. This paper: (1) describes a method for evaluating the clarity of friction ridge impressions by using color-coded annotations that can be used by examiners or automated systems; (2) discusses algorithms for overall clarity metrics based on manual or automated clarity annotation; and (3) defines a method of quantifying the correspondence of clarity when comparing a pair of friction ridge images, based on clarity annotation and resulting metrics. Different uses of this approach include examiner interchange of data, quality assurance, metrics, and as an aid in automated fingerprint matching.

  18. Vertical ridge augmentation using the modified shell technique--a case series.

    Science.gov (United States)

    Stimmelmayr, Michael; Beuer, Florian; Schlee, Markus; Edelhoff, Daniel; Güth, Jan-Frederik

    2014-12-01

    Vertical defects of the alveolar crest often restrict the placement of implants. The outcome of vertical augmentation is unpredictable so we aimed to develop a technique that has predictable results. We used autogenous grafts trimmed to shells less than 1mm thick to rebuild the vertical dimensions of the alveolar ridge. The shells were fixed with microscrews and the vertical space between the shell and the residual bone was filled with autogenous particulate bone. Vertical dimensions before and after augmentation were measured and descriptive statistics calculated. A total of 17 patients (10 female, 7 male, mean (SD) age 46 (17) years) had 18 sites augmented (2 sites in one patient). In 2 cases the wound dehisced and healing was by secondary intention. The rest healed uneventfully. The mean (SD) vertical defect was 4.7 (1.4) mm and mean (SD) resorption during consolidation was 0.5 (0.7) mm. All 30 previously planned implants were placed, and none failed during the first year. Loading was monitored for a mean (SD) period of 14.6 (10.5) months. The technique showed promising results and could be an alternative to procedures that use extraoral donor sites. Copyright © 2014 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  19. The efficacy of hydrothermally obtained carbonated hydroxyapatite in healing alveolar bone defects in rats with or without corticosteroid treatment

    Directory of Open Access Journals (Sweden)

    Marković Dejan

    2014-01-01

    Full Text Available Background/Aim. Autogenous bone grafting has been the gold standard in clinical cases when bone grafts are required for bone defects in dentistry. The study was undertaken to evaluate multilevel designed carbonated hydroxyapatite (CHA obtained by hydrothermal method, as a bone substitute in healing bone defects with or without corticosteroid treatment in rats as assessed by histopathologic methods. Methods. Bone defects were created in the alveolar bone by teeth extraction in 12 rats. The animals were initially divided into two groups. The experimental group was pretreated with corticosteroids: methylprednisolone and dexamethasone, intramuscularly, while the control group was without therapy. Posterior teeth extraction had been performed after the corticosteroid therapy. The extraction defects were fulfilled with hydroxyapatite with bimodal particle sizes in the range of 50-250 μm and the sample from postextocactional defect of the alveolar bone was analyzed pathohystologically. Results. The histopatological investigations confirmed the biologic properties of the applied material. The evident growth of new bone in the alveolar ridge was clearly noticed in both groups of rats. Carbonated HA obtained by hydrothermal method promoted bone formation in the preformed defects, confirming its efficacy for usage in bone defects. Complete resorption of the material’s particles took place after 25 weeks. Conclusion. Hydroxyapatite completely meets the clinical requirements for a bone substitute material. Due to its microstructure, complete resorption took place during the observation period of the study. Corticosteroid treatment did not significantly affect new bone formation in the region of postextractional defects. [Projekat Ministarstva nauke Republike Srbije, br. 172026

  20. Partial pulmonary embolization disrupts alveolarization in fetal sheep

    Directory of Open Access Journals (Sweden)

    Hooper Stuart B

    2010-04-01

    Full Text Available Abstract Background Although bronchopulmonary dysplasia is closely associated with an arrest of alveolar development and pulmonary capillary dysplasia, it is unknown whether these two features are causally related. To investigate the relationship between pulmonary capillaries and alveolar formation, we partially embolized the pulmonary capillary bed. Methods Partial pulmonary embolization (PPE was induced in chronically catheterized fetal sheep by injection of microspheres into the left pulmonary artery for 1 day (1d PPE; 115d gestational age; GA or 5 days (5d PPE; 110-115d GA. Control fetuses received vehicle injections. Lung morphology, secondary septal crests, elastin, collagen, myofibroblast, PECAM1 and HIF1α abundance and localization were determined histologically. VEGF-A, Flk-1, PDGF-A and PDGF-Rα mRNA levels were measured using real-time PCR. Results At 130d GA (term ~147d, in embolized regions of the lung the percentage of lung occupied by tissue was increased from 29 ± 1% in controls to 35 ± 1% in 1d PPE and 44 ± 1% in 5d PPE fetuses (p VEGF and Flk-1, although a small increase in PDGF-Rα expression at 116d GA, from 1.00 ± 0.12 in control fetuses to 1.61 ± 0.18 in 5d PPE fetuses may account for impaired differentiation of alveolar myofibroblasts and alveolar development. Conclusions PPE impairs alveolarization without adverse systemic effects and is a novel model for investigating the role of pulmonary capillaries and alveolar myofibroblasts in alveolar formation.

  1. Cancer and fertility preservation

    DEFF Research Database (Denmark)

    Lambertini, Matteo; Del Mastro, Lucia; Pescio, Maria C

    2016-01-01

    cryopreservation and embryo/oocyte cryopreservation are standard strategies for fertility preservations in male and female patients, respectively; other strategies (e.g. pharmacological protection of the gonads and gonadal tissue cryopreservation) are considered experimental techniques. However, since then, new......In the last years, thanks to the improvement in the prognosis of cancer patients, a growing attention has been given to the fertility issues. International guidelines on fertility preservation in cancer patients recommend that physicians discuss, as early as possible, with all patients...... of reproductive age their risk of infertility from the disease and/or treatment and their interest in having children after cancer, and help with informed fertility preservation decisions. As recommended by the American Society of Clinical Oncology and the European Society for Medical Oncology, sperm...

  2. Incorporating Ridges with Minutiae for Improved Fingerprint verification

    Directory of Open Access Journals (Sweden)

    Ms.M.Indra

    2012-10-01

    Full Text Available Next to DNA, fingerprint is the unique feature which identifies the individual. Distortions and skin deformations makes the fingerprint unreliable and it is difficult to match using minutiae alone. But when ridge features are incorporated with minutiae features (minutiae type, orientation and position more topological information can be obtained. And also ridges are invariant to transformations such as rotation and translation[1]. Ridge based coordinate system is used to extract the ridge features such as ridge length, ridge count, ridge type and curvature direction in the skeletonized image. Breadth First Search is used to traverse the graph formed using the minutiae as the node and the ridge vector formed using the ridge features as the edge. The proposed ridge feature gives additional information for fingerprint matching with little increment in template size and can be used along with the existing minutiae features to increase the accuracy and robustness of fingerprint recognition systems.

  3. Advanced Digital Preservation

    CERN Document Server

    Giaretta, David

    2011-01-01

    There is growing recognition of the need to address the fragility of digital information, on which our society heavily depends for smooth operation in all aspects of daily life. This has been discussed in many books and articles on digital preservation, so why is there a need for yet one more? Because, for the most part, those other publications focus on documents, images and webpages -- objects that are normally rendered to be simply displayed by software to a human viewer. Yet there are clearly many more types of digital objects that may need to be preserved, such as databases, scientific da

  4. Moving Image Preservation in Libraries.

    Science.gov (United States)

    De Stefano, Paula

    2003-01-01

    Examines the current practices of film and video preservation in libraries and examines barriers that have hindered the development of full-fledged preservation programs for them. Topics include advances in education and training; preservation paradigms; and mechanics of film production that affect preservation. (Author/LRW)

  5. Coronectomy versus surgical removal of the lower third molars with a high risk of injury to the inferior alveolar nerve. A bibliographical review

    Science.gov (United States)

    Moreno-Vicente, Javier; Schiavone-Mussano, Rocío; Clemente-Salas, Enrique; Marí-Roig, Antoni; Jané-Salas, Enric

    2015-01-01

    Background Coronectomy is the surgical removal of the crown of the tooth deliberately leaving part of its roots. This is done with the hope of eliminating the pathology caused, and since the roots are still intact, the integrity of the inferior alveolar nerve is preserved. Objectives The aim is to carry out a systematic review in order to be able to provide results and conclusions with the greatest scientific evidence possible. Material and Methods A literature review is carried out through the following search engines: Pubmed MEDLINE, Scielo, Cochrane library and EMI. The level of evidence criteria from the Agency for Healthcare Research and Quality was applied, and the clinical trials’ level of quality was analyzed by means of the JADAD criteria. Results The following articles were obtained which represents a total of 17: 1 systematic review, 2 randomized clinical trials and 2 non-randomized clinical trials, 3 cohort studies, 2 retrospective studies, 3 case studies and 4 literature reviews. Conclusions Coronectomy is an adequate preventative technique in protecting the inferior alveolar nerve, which is an alternative to the conventional extraction of third molars, which unlike the former technique, presents a high risk of injury to the inferior alveolar nerve. However, there is a need for new clinical studies, with a greater number of samples and with a longer follow-up period in order to detect potential adverse effects of the retained roots. Key words: Coronectomy, inferior alveolar nerve, nerve injury, wisdom tooth removal, paresthesia, and systematic review. PMID:25858081

  6. Experimental study on instant site preservation techniques in fresh anterior extraction sockets%前牙区拔牙位点即刻保存的动物实验研究

    Institute of Scientific and Technical Information of China (English)

    于博涵; 邓春富; 赵宝红; 张翀

    2011-01-01

    Objective To assess the histomorphological and contour changes of the extraction sockets after site preservation.Methods In six hybrid dogs, the second maxillary and mandibular incisors were extracted.The sockets of one side were filled with osteoinduction active mature ( OAM) , senring as the experimental group, and the other side was left for spontaneous healing, serving as the control.After 3 months, the animals were sacrificed and the samples were collected for histomorphological and contour evaluation with image analysis.Results In both groups contour shrinkage and bone loss were showed but resorption was significantjy lower in experimental group than in control group ( P < 0.001 ) .Conclusion Site preservation techniques can significantly reduce alveolar ridge resorption after tooth exraction.%目的 评估经位点保存技术处理后牙槽窝组织形态计量学上的改变.方法 拔除6条杂种犬各自上、下颌两侧第二切牙,随机分两组,在一侧即刻填入骨诱导活性材料,为实验组;另一侧不作处理,对照组.术后3个月处死获得样本,利用图像分析进行组织计量及形态的评估.结果 所有位点骨量均有不同程度的吸收.图像分析显示,实验组平均骨量吸收程度显著低于对照组(P<0.001).结论 牙齿拔除后,拔牙窝位点保存技术的应用能明显减少牙槽嵴萎缩吸收程度.

  7. Alveolar targeting of aerosol pentamidine. Toward a rational delivery system

    Energy Technology Data Exchange (ETDEWEB)

    Simonds, A.K.; Newman, S.P.; Johnson, M.A.; Talaee, N.; Lee, C.A.; Clarke, S.W. (Royal Free Hospital, London (England))

    1990-04-01

    Nebulizer systems that deposit a high proportion of aerosolized pentamidine on large airways are likely to be associated with marked adverse side effects, which may lead to premature cessation of treatment. We have measured alveolar deposition and large airway-related side effects (e.g., cough, breathlessness, and effect on pulmonary function) after aerosolization of 150 mg pentamidine isethionate labeled with {sup 99m}Tc-Sn-colloid. Nine patients with AIDS were studied using three nebulizer systems producing different droplet size profiles: the Acorn System 22, Respirgard II, and Respirgard II with the inspiratory baffle removed. Alveolar deposition was greatest and side effects least with the nebulizer producing the smallest droplet size profile (Respirgard II), whereas large airway-related side effects were prominent and alveolar deposition lowest with the nebulizer producing the largest droplet size (Acorn System 22). Values for alveolar deposition and adverse airway effects were intermediate using the Respirgard with inspiratory baffle removed, thus indicating the importance of the baffle valve in determining droplet size. Addition of a similar baffle valve to the Acorn System 22 produced a marked improvement in droplet size profile. Selection of a nebulizer that produces an optimal droplet size range offers the advantage of enhancing alveolar targeting of aerosolized pentamidine while reducing large airway-related side effects.

  8. Composition of alveolar liquid in the foetal lamb.

    Science.gov (United States)

    Adamson, T M; Boyd, R D; Platt, H S; Strang, L B

    1969-09-01

    1. Experiments were performed on foetal lambs at gestations between 125 days and term. The foetus was exteriorized at Caesarean section with the umbilical cord and placental attachment maintained intact. Samples of liquid from the alveolar parts of the lung were withdrawn through a tracheal cannula and samples of lung lymph, plasma and amniotic liquid were also obtained. Measurements were made of total osmolality, concentrations of electrolytes and urea, pH and P(CO2). Titrations were carried out with N/10 HCl and N/10 NaOH. The water content of the liquids was estimated and concentrations expressed per kg H(2)O.2. In alveolar liquid [H(+)], [K(+)] and [Cl(-)] were higher and [Ca(2+)], [phosphates] and [HCO(3) (-)] were lower than in plasma or lymph. In amniotic liquid osmolality [Na(+)], [Cl(-)] and [Ca(2+)] were lower and [phosphates] higher than in plasma or lymph. Alveolar liquid/plasma ratios of [HCO(3) (-)], [Ca(2+)], [Cl(-)] and [K(+)] differed from ultra filtrate/plasma ratios of these ions.3. Titration curves demonstrated a very small amount of buffering in alveolar liquid at its in vivo pH of 6.27 mostly due to HCO(3) (-) at an average concentration of 2.8 mM/kg H(2)O.4. It is concluded that foetal alveolar liquid is not an ultrafiltrate of plasma nor a mixture of amniotic liquid and plasma ultrafiltrate, but a special material elaborated by the foetal lung.

  9. Is alveolar cleft reconstruction still controversial? (Review of literature

    Directory of Open Access Journals (Sweden)

    Sameh A. Seifeldin

    2016-01-01

    Full Text Available Cleft lip and palate (CL/P is a frequent congenital malformation that manifests in several varieties including unilateral or bilateral and complete or incomplete. Alveolar cleft reconstruction remains controversial with regard to timing, graft materials, surgical techniques, and methods of evaluation. Many studies have been conducted addressing these points to develop an acceptable universal protocol for managing CL/P. The primary goal of alveolar cleft reconstruction in CL/P patients is to provide a bony bridge at the cleft site that allows maxillary arch continuity, oronasal fistula repair, eruption of the permanent dentition into the newly formed bone, enhances nasal symmetry through providing alar base support, orthodontic movement and placement of osseointegrated implants when indicated. Other goals include improving speech, improvement of periodontal conditions, establishing better oral hygiene, and limiting growth disturbances. In order to rehabilitate oral function in CL/P patients alveolar bone grafting is necessary. Secondary bone grafting is the most widely accepted method for treating alveolar clefts. Autogenous bone graft is the primary source for reconstructing alveolar cleft defects and is currently the preferred grafting material.

  10. Preserving Southwest Virginia's Folklore.

    Science.gov (United States)

    Burgin, Ramond

    1997-01-01

    Describes Southwest Virginia's rich tradition of folklore and culture and the need for its preservation. Summarizes the author's time-consuming process of preparing an inventory and indexing the vast archival collections gathered by students in American Folklore classes at Mountain Empire Community College and by the Southwest Virginia Folklore…

  11. POLARISATION PRESERVING OPTICAL FIBRE

    DEFF Research Database (Denmark)

    2000-01-01

    . This cladding structure provides polarisation preserving properties to the optical fibre. Optical fibres using this technology may have claddings with elements placed non-periodically as well as in a two-dimensional periodic lattice - such as cladding providing Photonic Band Gap (PBG) effects....

  12. Preservation in New Buildings

    Directory of Open Access Journals (Sweden)

    Christopher Kitching

    2000-06-01

    Full Text Available In the United Kingdom (as in many other countries increasing attention is being paid to the importance of each library and archive having a written preservation strategy endorsed by its governing body. So increasingly we are asking: where does „preservation“ begin and what are its top priorities? Some would say preservation begins with the definition of collecting policies to ensure that only relevant items are acquired in the first place, and therefore that no unnecessary costs are incurred on the long-term care of unwanted and unconsulted items. Others might argue that the first priority must be the careful appraisal of existing holdings to determine their preservation and conservation requirements and to prioritise their treatment. Or should preservation begin with damage-limitation: restricting the physical handling of books and documents, on the one hand by providing whenever possible surrogate copies in digital formats or microform, and on the other hand by offering at least basic protection through appropriate boxing and packaging? This, surely, goes hand-in-hand with the education of staff and readers about the importance of treating rare or unique materials with proper respect.

  13. Paints and Preservatives.

    Science.gov (United States)

    Powell, Larry E.; Miller, Larry E.

    The publication contains an outline for use by agriculture teachers in developing a teaching plan for a unit on paints and preservatives. The topics included are (1) recognizing, solving, and preventing paint problems and (2) operating and using power spray painting equipment. Items presented for each topic are: the situation, (intended to inform…

  14. Formation and stability of ridge-ridge-ridge triple junctions in rheologically realistic lithosphere model

    Science.gov (United States)

    Gerya, Taras; Burov, Evgueni

    2015-04-01

    -branch junction formation and evolution by using high-resolution 3D numerical mechanical experiments that take into account realistic thermo-rheological structure and rheology of the lithosphere. We find that two major types of quadruple and triple junctions are formed under bi-directional or multidirectional far-field stress field: (i) plate rifting junctions are formed by the initial plate fragmentation and can be subsequently re-arranged into (ii) oceanic spreading junctions controlled by the new oceanic crust accretion. In particular, we document initial formation and destabilization of quadruple R-R-R-R junctions as initial plate rifting structures under bi-directional extension. In most cases, quadruple plate rifting junctions rapidly (typically within 1-2 Myr) evolve towards formation of two diverging triple oceanic spreading junctions connected by a linear spreading center lengthening with time. This configuration remains stable over long time scales. However, under certain conditions, quadruple junctions may also remain relatively stable. Asymmetric stretching results in various configurations, for example formation of "T-junctions" with trans-extensional components and combination of fast and slow spreading ridges. Combined with plume impingement, this scenario evolves in realistic patterns closely resembling observed plate dynamics. In particular, opening of the Red Sea and of the Afar rift system find a logical explanation within a single model. Numerical experiments also suggest that several existing oceanic spreading junctions form as the result of plate motions rearrangements after which only one of two plates spreading along the ridge become subjected to bi-directional spreading.

  15. Lateral trap-door window approach with maxillary sinus membrane lifting for dental implant placement in atrophied edentulous alveolar ridge

    Directory of Open Access Journals (Sweden)

    Shou-Yen Kao

    2015-02-01

    Full Text Available One of the most challenging and technically sensitive surgical procedures in conjunction with dental implant rehabilitation is sinus membrane lifting to increase the bone height or volume from the maxillary sinus floor. This important preprosthetic surgical technique has been available for >15 years, making possible the creation of bone volume in the edentulous posterior maxilla for the placement of dental implants in surgically compromised cases. Substantial literature exists regarding the most efficacious way to increase the predictability of this surgical procedure, and reduce its associated complications. In this article, we describe the regional anatomy of the maxillary sinus, the evolution of the sinus membrane lifting procedure, the current surgical technique, its survival rate and associated complications, the need for bone graft or bone substitutes, and current advances in the lateral approach through a trap-door window for sinus membrane lifting for dental implants.

  16. Methodological approach for the evaluation of homologous bone graft use in post-extractive atrophic alveolar ridges

    Directory of Open Access Journals (Sweden)

    B. Musante

    2013-01-01

    Full Text Available The aim of this study is to investigate the in vivo efficacy of Puros® cancellous particulate allograft bone in the regeneration of post-extractive sites. Twelve molar or premolar sites were selected. Seven days after minimally invasive tooth extraction, Puros® cancellous particulate allografts were inserted into the elected sites. TC Cone-Beam investigation and at 4 months from surgery; bone height and width were evaluated. Five months after surgery, biopsy samples of the regenerated sites were taken and histologically analyzed to qualitatively evaluate bone regeneration. TC analysis showed, a mean bone gain of 4.1 mm in height and 2.02 mm in width. The histological analysis of the samples showed intense bone metabolic activity with active osteoblasts on the implant surface, at the level of the native bone-graft interface and in the grafted area. The radiographic and histological analyses demonstrate an optimal bonen regeneration, both in terms of quality and quantity using Puros®.

  17. Preliminary results from the first InRidge cruise to the central Indian Ridge

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R.; Murthy, K.S.R.; Iyer, S.D.; Rao, M.M.M.; Banerjee, R.; Subrahmanyam, A.S.; Shirodkar, P.V.; Ghose, I.; Ganesan, P.; Rao, A.K.; Suribabu, A.; Ganesh, C.; Naik, G.P.

    stream_size 1 stream_content_type text/plain stream_name Inter_Ridge_News_7_40.pdf.txt stream_source_info Inter_Ridge_News_7_40.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  18. Tomographic Evaluation of Prevalence, Position, and Diameter of the Intraosseous Branch of the Posterior Superior Alveolar Artery in Fully Edentulous Individuals.

    Science.gov (United States)

    de Oliveira, Guilherme José Pimentel Lopes; Abdala, Marciel Antônio; Nary-Filho, Hugo; Sakakura, Celso Eduardo; Garcia, Valdir Gouveia; Leite, Felipe Coletti

    2017-03-21

    The objective of this study was to evaluate the presence, position, and diameter of the intraosseous branch (IObr) of the posterior superior alveolar artery in fully edentulous patients. Two-hundred five computed tomography scans of fully edentulous patients were analyzed. The presence of the IObr was investigated in the coronal plane at the lateral wall of the maxillary sinus. In patients in whom the IObr was detected, the artery diameter was measured, and the distance from the artery to the bone crest of the alveolar ridge, the maxillary sinus floor, and the distance of the maxillary sinus floor to the bone crest of the alveolar ridge were measured as well. A descriptive statistical analysis of these parameters was conducted. The IObr was identified in the maxillary sinus in 105 tomography images (51.2%), and its diameter varied between 0.8 and 3.3 mm (1.29 ± 0.49 mm). The IObr presented with an artery diameter less than 1 mm in 29% of the patients, between 1 and 2 mm diameter in 61% of the patients and with a diameter larger than 2 mm in 10% of patients. Regarding the IObr topography, the distance from the artery to the floor of the maxillary sinus was 9.62 ± 4.59 mm, and the distance from the artery to the top of crestal bone was 15.15 ± 4.47 mm. At least 10% of edentulous patients are at risk of bleeding complications during interventions in the maxillary sinus.

  19. Evolution of radiative sand ridge field of the South Yellow Sea and its sedimentary characteristics

    Institute of Scientific and Technical Information of China (English)

    王颖; 朱大奎; 尤坤元; 潘少明; 朱晓东; 邹欣庆; 张永战

    1999-01-01

    A sand ridge field of 22 470 km~2 consists of fine sands and silts originally from the old Changjiang River sediment during the late Pleistocene period. Late Holocene sand stratum with its well-preserved laminary bedding of more clay particles reflects the influence from the Yellow River. There are three genetic types of morphology of sand ridge field as follows: (ⅰ) reformed alluvial sandy bodies and old river valleys, located in the central and southern parts, formed from the end of Pleistocene to the present. (ⅱ) Radiative current ridges and patrimonal valley type, located in the northeastern part, formed during the early or middle Holocene time. (ⅲ) Eroded-depositional sandy bodies in the north and outer parts, and erosional trough in the north formed since the middle Holocene transgression. The sand ridge field has a periodic nature of developing processes: the period of sediment accumulation by rivers during cold epoch with low sea level and the period of erosional formation by tidal currents d

  20. Generalized Potentiometric Surface of the Arikaree Aquifer, Pine Ridge Indian Reservation and Bennett County, South Dakota

    Science.gov (United States)

    Carter, Janet M.; Heakin, Allen J.

    2007-01-01

    INTRODUCTION The Pine Ridge Indian Reservation and Bennett County are located in southwest South Dakota. The Pine Ridge Indian Reservation includes all of Shannon County and the part of Jackson County south of the White River. Extensive Indian trust lands are in Bennett County. For purposes of this map, the Pine Ridge Indian Reservation and all of Bennett County are included in the study area (sheet 1). Ground water from wells and springs is the predominant source of public and domestic supply within the study area. The Arikaree aquifer is the largest source of ground water throughout this area. The Oglala Sioux Tribe is developing a ground-water management plan designed to ?preserve, protect and maintain the quality of ground water for living and future members and non-members of the Oglala Sioux Indian Tribe within the internal and external boundaries of the Pine Ridge Reservation? (Michael Catches Enemy, Oglala Sioux Tribe Natural Resources Regulatory Agency, oral commun., 2007). Hydrologic information about the Arikaree aquifer is important to managing this resource. In 1998, the U.S. Geological Survey (USGS) began working in cooperation with the Oglala Sioux Tribe to develop a potentiometric map of the Arikaree aquifer in Jackson and Shannon Counties, with a primary component of that effort being a well inventory in those counties. In 2003, the study area was expanded to include Bennett County.

  1. Alveolar-filling growth pattern of sarcomatoid malignant pleural mesothelioma.

    Science.gov (United States)

    Hayakawa, Takamitsu; Tajima, Shogo; Takanashi, Yusuke; Takahashi, Tsuyoshi; Neyatani, Hiroshi; Funai, Kazuhito

    2016-09-01

    A case of sarcomatoid malignant pleural mesothelioma showing extremely rare growth pattern is described. A 63-year-old man presented to our hospital with left pleural effusion. A computed tomography (CT) scan of the chest showed diffusely thickened left visceral and parietal pleura associated with intermingled pulmonary infiltrative shadowing. Biopsy of the pleura under general anaesthesia confirmed the diagnosis of sarcomatoid malignant pleural mesothelioma. The patient underwent left extra-pleural pneumonectomy. Histopathologically, the sarcomatoid spindle tumour cells changed their morphology to polygonal cells in the pulmonary parenchyma and grew upwards, filling the alveolar space without the destruction of its septa, showing an alveolar-filling growth pattern. The current report indicates a case of sarcomatoid pleural mesothelioma that shows an alveolar-filling growth pattern, despite having not been thoroughly categorized in the World Health Organization (WHO) classification.

  2. Neutrophil-induced injury of rat pulmonary alveolar epithelial cells.

    Science.gov (United States)

    Simon, R H; DeHart, P D; Todd, R F

    1986-11-01

    The damage to pulmonary alveolar epithelial cells that occurs in many inflammatory conditions is thought to be caused in part by phagocytic neutrophils. To investigate this process, we exposed monolayers of purified rat alveolar epithelial cells to stimulated human neutrophils and measured cytotoxicity using a 51Cr-release assay. We found that stimulated neutrophils killed epithelial cells by a process that did not require neutrophil-generated reactive oxygen metabolites. Pretreatment of neutrophils with an antibody (anti-Mo1) that reduced neutrophil adherence to epithelial cells limited killing. Although a variety of serine protease inhibitors partially inhibited cytotoxicity, we found that neutrophil cytoplasts, neutrophil lysates, neutrophil-conditioned medium, purified azurophilic or specific granule contents, and purified human neutrophil elastase did not duplicate the injury. We conclude that stimulated neutrophils can kill alveolar epithelial cells in an oxygen metabolite-independent manner. Tight adherence of stimulated neutrophils to epithelial cell monolayers appears to promote epithelial cell killing.

  3. Alveolar rhabdomyosarcoma involving the mandibular ramus and its surrounding tissues

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Suk Ja; Kang, Byung Cheol [Chonnam National University College of Medicine, Gwangju (Korea, Republic of)

    2004-06-15

    Rhabdomyosarcoma, when it occurs in the head and neck, is primarily found in children. Alveolar rhabdomyosarcoma is rarely seen in the oral lesion, comparing to the embryonal and the pleomorphic variants. This is a report of a case of alveolar rhabdomyosarcoma in the mandible in a ten-year old girl who complained of a non-painful swelling on the right cheek. The right lower 1st molar was mobile. Her radiographs revealed an extensive radiolucency with somewhat irregular border on the right mandibular ramus. The right mandibular 1st and 2nd molars lost their lamina dura and were floating. CT images revealed smooth-outlined soft tissue mass occupying the pterygomandibular space, the infratemporal space, and the masseteric muscle with thinning and perforation of the right mandibular angle and ramus. Histopathological and immunohistochemical findings established the final diagnosis of alveolar rhabdomyosarcoma.

  4. Electronic thermography for the assessment of inferior alveolar nerve deficit.

    Science.gov (United States)

    Gratt, B M; Shetty, V; Saiar, M; Sickles, E A

    1995-08-01

    Neurosensory deficit is one of the major complications encountered in oral and maxillofacial surgery. OBJECTIVES. To determine the efficacy of electronic thermography in objectively assessing neurosensory deficits of the inferior alveolar nerve. STUDY DESIGN. Three studies were conducted measuring skin temperature over the chin region of the face at 0.1 degree C accuracy. RESULTS. (1) Thermal symmetry of the chin region in normal subjects (delta T = 0.2 degree C, SD = 0.02 degree C); (2) Induction of transient thermal asymmetry by local anesthetic injection (delta T = +0.4 degree C, SD = 0.2 degree C); (3) nine subjects with neurologic alterations of the inferior alveolar nerve (delta T = +0.5 degree C, SD = 0.2 degree C). Statistically significant differences were found between control group and experimental groups at p alveolar nerve injury or by pharmacologic nerve block.

  5. Traumatic neuroma of the inferior alveolar nerve: a case report.

    Science.gov (United States)

    Arribas-García, Ignacio; Alcalá-Galiano, Andrea; Gutiérrez, Ramón; Montalvo-Moreno, Juan José

    2008-03-01

    Traumatic neuromas are rare entities which characteristically arise subsequently to surgery and are usually accompanied by pain, typically neuralgic. We present an unusual case of an intraosseous traumatic neuroma of the inferior alveolar nerve following tooth extraction. A 56-year-old man consulted for paresthesias and hyperesthesia in the left mandibular region following extraction of the left mandibular third molar (#38). The panoramic radiograph revealed a radiolucent lesion in the inferior alveolar nerve canal, and CT demonstrated the existence of a mass within the canal, producing widening of the same. Nerve-sparing excisional biopsy was performed. Histopathology and immunohistochemistry were consistent with traumatic neuroma of the left inferior alveolar nerve. After 3 years of follow-up, the patient is asymptomatic and there are no signs of recurrence.

  6. Recent advances in alveolar biology: evolution and function of alveolar proteins.

    Science.gov (United States)

    Orgeig, Sandra; Hiemstra, Pieter S; Veldhuizen, Edwin J A; Casals, Cristina; Clark, Howard W; Haczku, Angela; Knudsen, Lars; Possmayer, Fred

    2010-08-31

    This review is focused on the evolution and function of alveolar proteins. The lung faces physical and environmental challenges, due to changing pressures/volumes and foreign pathogens, respectively. The pulmonary surfactant system is integral in protecting the lung from these challenges via two groups of surfactant proteins - the small molecular weight hydrophobic SPs, SP-B and -C, that regulate interfacial adsorption of the lipids, and the large hydrophilic SPs, SP-A and -D, which are surfactant collectins capable of inhibiting foreign pathogens. Further aiding pulmonary host defence are non-surfactant collectins and antimicrobial peptides that are expressed across the biological kingdoms. Linking to the first symposium session, which emphasised molecular structure and biophysical function of surfactant lipids and proteins, this review begins with a discussion of the role of temperature and hydrostatic pressure in shaping the evolution of SP-C in mammals. Transitioning to the role of the alveolus in innate host defence we discuss the structure, function and regulation of antimicrobial peptides, the defensins and cathelicidins. We describe the recent discovery of novel avian collectins and provide evidence for their role in preventing influenza infection. This is followed by discussions of the roles of SP-A and SP-D in mediating host defence at the alveolar surface and in mediating inflammation and the allergic response of the airways. Finally we discuss the use of animal models of lung disease including knockouts to develop an understanding of the role of these proteins in initiating and/or perpetuating disease with the aim of developing new therapeutic strategies.

  7. Remedial Investigation Work Plan for Chestnut Ridge Operable Unit 1 (Chestnut Ridge Security Pits) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    This document outlines the activities necessary to conduct a Remedial Investigation (RI) of the Chestnut Ridge Security Pits (CRSP) at the Oak Ridge Y-12 Plant. The CRSP, also designated Chestnut Ridge Operable Unit (OU) 1, is one of four OUs along Chestnut Ridge on the Oak Ridge Reservation (ORR). The purpose of the RI is to collect data to (1) evaluate the nature and extent of known and suspected contaminants, (2) support an Ecological Risk Assessment (ERA) and a Human Health Risk Assessment (HHRA), (3) support the feasibility study in the development and analysis of remedial alternatives, and (4) ultimately, develop a Record of Decision (ROD) for the site. This chapter summarizes the regulatory background of environmental investigation on the ORR and the approach currently being followed and provides an overview of the RI to be conducted at the CRSP. Subsequent chapters provide details on site history, sampling activities, procedures and methods, quality assurance (QA), health and safety, and waste management related to the RI.

  8. Reconstruction of alveolar defects in patients with cleft lip and palate - 111 consecutive patients

    DEFF Research Database (Denmark)

    Andersen, Kristian

    2012-01-01

    Reconstruction of alveolar defects in patients with cleft lip and palate - 111 consecutive patients......Reconstruction of alveolar defects in patients with cleft lip and palate - 111 consecutive patients...

  9. Thermal behavior of premises equipped with different alveolar structures

    Directory of Open Access Journals (Sweden)

    Lajimi Nour

    2015-01-01

    Full Text Available This paper presents a numerical study of local thermal behavior. Vertical walls are equipped with alveolar structure and/or simple glazing in East, South and West frontages. Local temperature is assumed to be variable with time or imposed at set point temperature. Results principally show that the simple glazing number has a sensitive effect on convection heat transfer and interior air temperature. They also show that the diode effect is more sensitive in winter. The effect of alveolar structure and simple glazing on the power heating in case with set point temperature is also brought out.

  10. From alveolar diffuse atrophy to aggressive periodontitis: a brief history.

    Science.gov (United States)

    Guzeldemir, Esra; Toygar, Hilal Uslu

    2006-01-01

    Technologic advances in mechanics, electronics, physics, chemistry, and computer science have contributed to advances in dental medicine. Periodontology is not only a clinical science but is also directly related to the basic sciences. Research is conducted in laboratories rather than in clinics now. During the last century, aggressive periodontitis has received attention from numerous researchers because of its multifactorial features. This paper explores the long scientific journey of aggressive periodontitis, beginning with its first definition as alveolar diffuse atrophy. Perhaps in the future, "alveolar diffuse atrophy" will be referred to by another name or term. However, this journey will never end.

  11. Alveolar hemorrhage as the initial presentation of systemic lupus erythematosus.

    Science.gov (United States)

    de Holanda, Bruna A; Barreto, Isabela G Menna; de Araujo, Isadora S Gomes; de Araujo, Daniel B

    2016-01-01

    Alveolar hemorrhage (AH) is a rare syndrome that can often occur in autoimmune diseases, blood clotting disorders, infection or by acute inhalation injury, presenting rapid evolution and high mortality, especially with late diagnosis and treatment. Among the autoimmune diseases, there are reported cases in patients with primary antiphospholipid syndrome (PAPS), vasculitis and systemic lupus erythematosus (SLE). An early diagnosis is an essential tool in the successful management of this complication, requiring aggressive treatment based on vigorous immunosuppression and broad-spectrum antibiotic. We describe here a case of alveolar hemorrhage associated with glomerulonephritis as the open presentation in a patient with SLE.

  12. Alveolar hemorrhage as the initial presentation of systemic lupus erythematosus

    Science.gov (United States)

    de Holanda, Bruna A.; Barreto, Isabela G. Menna; de Araujo, Isadora S. Gomes

    2016-01-01

    Alveolar hemorrhage (AH) is a rare syndrome that can often occur in autoimmune diseases, blood clotting disorders, infection or by acute inhalation injury, presenting rapid evolution and high mortality, especially with late diagnosis and treatment. Among the autoimmune diseases, there are reported cases in patients with primary antiphospholipid syndrome (PAPS), vasculitis and systemic lupus erythematosus (SLE). An early diagnosis is an essential tool in the successful management of this complication, requiring aggressive treatment based on vigorous immunosuppression and broad-spectrum antibiotic. We describe here a case of alveolar hemorrhage associated with glomerulonephritis as the open presentation in a patient with SLE. PMID:27994272

  13. Educating for preserving biodiversity

    Directory of Open Access Journals (Sweden)

    Méndez, I. E.

    2014-01-01

    Full Text Available The notion of “culture of diversity” is presented in a new dimension. “That of educating for preserving biodiversity” is advanced together with its main challenges. The need of educating the masses for preserving biodiversity is perhaps the most outstanding to be faced, particularly if pedagogic requirements and the diversity of population is to be met. Likewise, it should help to put individuals in contact with the many elements conforming biodiversity and lead them to recognize its value ethically and esthetically. The research presents the framework for designing educating programs enhancing the genetic level, the ecosystem and the qualitative dimension and including materials and energy flood and its meaning for the homeostasis and autopoiesis of the system, together with its interactions with other components for achieving an equilibrium and stability. The importance of the natural evolution tendency is highlighted.

  14. Patch test with preservatives

    Directory of Open Access Journals (Sweden)

    Kar Sumit

    1992-01-01

    Full Text Available Of the 705 patients patch tested between March 88 to March 91, 317 were tested for sensitivity to preservatives with antigens obtained from Chemo technique AB, Sweden. Paraben was the commonest sensitizer (22.4% followed by Groton B K (8.1% and Triclosan (6.5%. We stress the need to consider these allergens as source of dermatitis and advocate complete labelling of topical preparations marketed.

  15. E-space preservation.

    Science.gov (United States)

    Sonis, Andrew; Ackerman, Marc

    2011-11-01

    To determine the relationship of E-space preservation with lingual holding arches to mandibular permanent second molar impaction. Two hundred consecutively treated patients undergoing nonextraction treatment for incisor crowding were entered into the study. Lower incisor crowding was assessed by the Little Irregularity Index. Treatment involved E-space preservation via a passive lingual arch placed prior to exfoliation of the second primary molar. Panoramic and cephalometric radiographs were analyzed for any significant relationship of mandibular permanent second molar impaction relative to molar angulation, spacing, growth pattern, and skeletal relationships. Twenty-nine patients had at least one impacted second molar (14.5%). Of a possible 400 mandibular second molars, 34 were determined to be impacted (8.5%). Only the mandibular first molar-second molar angulation was found to be significant (P < .001). Pretreatment intermolar angulation of 24 degrees had a positive predictive value of 1. Impaction of permanent second mandibular molars in patients undergoing nonextraction via E-space preservation with a passive lingual arch is 10 to 20 times more prevalent than that observed in the general population. Risk of impaction is best predicted by the pretreatment intermolar angulation between first and second permanent mandibular molars.

  16. Bathymetry of Reykjanes Ridge: A methodological approach

    OpenAIRE

    Banul, Karolina, 1987-

    2014-01-01

    The sea floor is one of the Earths parts that still are mostly unexplored. Recent multibeam technology has now opened up new opportunities to increase our knowledge in this hitherto hidden part of the world. In this study part of the Reykjanes Ridge was analysed in order to create a high resolution and comprehensive topographic map of this northern part of the Mid-Atlantic Ocean Ridge. The general aims of the study were to i) develop seamless method from Caris, a raw analytical program for mu...

  17. Ridge and Transverse Correlation at Separated Rapidities

    CERN Document Server

    Chiu, Charles B

    2012-01-01

    A simple phenomenological relationship between the ridge distribution in $\\Delta\\eta$ and the single-particle distribution in $\\eta$ can be established from the PHOBOS data on both distributions. The implication points to the possibility that there is no long-range longitudinal correlation. An interpretation of the relationship is then developed, based on the recognition that longitudinal uncertainty of the initial configuration allows for non-Hubble-like expansion at early time. It is shown that the main features of the ridge structure can be explained in a model where transverse correlation stimulated by semihard partons is the principal mechanism.

  18. Serial bronchoscopic lung lavage in pulmonary alveolar proteinosis under local anesthesia

    Directory of Open Access Journals (Sweden)

    K Rennis Davis

    2015-01-01

    Full Text Available Pulmonary alveolar proteinosis (PAP is a rare disease, characterized by alveolar accumulation of surfactant composed of proteins and lipids due to defective surfactant clearance by alveolar macrophages. Mainstay of treatment is whole lung lavage, which requires general anesthesia. Herein, we report a case of primary PAP, successfully treated with serial bronchoscopic lung lavages under local anesthesia.

  19. The Usumacinta-Grijalva beach-ridge plain in southern Mexico: a high-resolution archive of river discharge and precipitation

    Science.gov (United States)

    Nooren, Kees; Hoek, Wim Z.; Winkels, Tim; Huizinga, Annika; Van der Plicht, Hans; Van Dam, Remke L.; Van Heteren, Sytze; Van Bergen, Manfred J.; Prins, Maarten A.; Reimann, Tony; Wallinga, Jakob; Cohen, Kim M.; Minderhoud, Philip; Middelkoop, Hans

    2017-09-01

    The beach-ridge sequence of the Usumacinta-Grijalva delta borders a 300 km long section of the southern Gulf of Mexico coast. With around 500 beach ridges formed in the last 6500 years, the sequence is unsurpassed in the world in terms of numbers of individual ridges preserved, continuity of the record, and temporal resolution. We mapped and dated the most extensively accreted part of the sequence, linking six phases of accretion to river mouth reconfigurations and constraining their ages with 14C and OSL dating. The geomorphological and sedimentological reconstruction relied on lidar data, coring transects, GPR measurements, grain-size analyses, and chemical fingerprinting of volcanic glass and pumice encountered within the beach and dune deposits. We demonstrate that the beach-ridge complex was formed under ample long-term fluvial sediment supply and shorter-term wave- and aeolian-modulated sediment reworking. The abundance of fluvially supplied sand is explained by the presence of easily weatherable Los Chocoyos ignimbrites from the ca. 84 ka eruption of the Atitlán volcano (Guatemala) in the catchment of the Usumacinta River. Autocyclic processes seem responsible for the formation of ridge-swale couplets. Fluctuations in their periodicity (ranging from 6-19 years) are governed by progradation rate, and are therefore not indicative of sea level fluctuations or variability in storm activity. The fine sandy beach ridges are mainly swash built. Ridge elevation, however, is strongly influenced by aeolian accretion during the time the ridge is located next to the beach. Beach-ridge elevation is negatively correlated with progradation rate, which we relate to the variability in sediment supply to the coastal zone, reflecting decadal-scale precipitation changes within the river catchment. In the southern Mexican delta plain, the coastal beach ridges therefore appear to be excellent recorders of hinterland precipitation.

  20. Geospatializing The Klang Gate Quartz Ridge in Malaysia: A Technological Perspective

    Science.gov (United States)

    Azahari Razak, Khamarrul; Mohamad, Zakaria; Zaki Ibrahim, Mohd; Azad Rosle, Qalam; Hattanajmie Abd Wahab, Mohd; Abu Bakar, Rabieahtul; Mohd Akib, Wan Abdul Aziz Wan

    2015-04-01

    and characterization of Quartz Ridge has shown promising results and advancing some hypothesis. The modern topographic laser scanning system proved suitable for such complex environment. The Quartz Ridge in Genting Klang, Selangor, believed to be the longest ridge in the world are now preserved in a digital form and can be quantitatively analysed. Many primary and secondary data can be generated and contributed to other studies, e.g. the determination of instability slope zone and rock-fall assessment along the ridge. Remarkably, this study is a first scientific exploration on the use of advanced geo-information tool, notably laser-based mapping to record, identify, and characterize the Quartz Ridge in Genting Klang, Selangor. The recent and modern geospatial data of tropical quartz in an urban forested environment provides technical and scientific spatial data of the longest quartz ridge. The geodatabase of Klang Gate Quartz Ridge allows the integration of multi-sensor-scales of remotely sensed data with other flora and fauna data in the area. As a conclusion, this study provides an accurate physical characteristic of prominent geological structures in Selangor, and its geospatial data is leading to a better compilation of comprehensive digital record of Quartz Ridge for conserving national geoheritage, promoting geotourism, and supporting its listing effort to the UNESCO's World Heritage Site in the near future.

  1. Normalization Ridge Regression in Practice I: Comparisons Between Ordinary Least Squares, Ridge Regression and Normalization Ridge Regression.

    Science.gov (United States)

    Bulcock, J. W.

    The problem of model estimation when the data are collinear was examined. Though the ridge regression (RR) outperforms ordinary least squares (OLS) regression in the presence of acute multicollinearity, it is not a problem free technique for reducing the variance of the estimates. It is a stochastic procedure when it should be nonstochastic and it…

  2. Contamination versus preservation of cosmetics

    DEFF Research Database (Denmark)

    Lundov, Michael Dyrgaard; Moesby, Lise; Zachariae, Claus

    2009-01-01

    cosmetics. In order to avoid contamination of cosmetics, the manufacturers add preservatives to their products. In the EU and the USA, cosmetics are under legislation and all preservatives must be safety evaluated by committees. There are several different preservatives available but the cosmetic market...... is dominated by a few preservatives: parabens, formaldehyde, formaldehyde releasers, and methylchloroisothiazolinone/methylisothiazolinone. Allergy to preservatives is one of the main reasons for contact eczema caused by cosmetics. Concentration of the same preservative in similar products varies greatly......, and this may indicate that some cosmetic products are over preserved. As development and elicitation of contact allergy is dose dependent, over preservation of cosmetics potentially leads to increased incidences of contact allergy. Very few studies have investigated the antimicrobial efficiency...

  3. Ridge regression estimator: combining unbiased and ordinary ridge regression methods of estimation

    Directory of Open Access Journals (Sweden)

    Sharad Damodar Gore

    2009-10-01

    Full Text Available Statistical literature has several methods for coping with multicollinearity. This paper introduces a new shrinkage estimator, called modified unbiased ridge (MUR. This estimator is obtained from unbiased ridge regression (URR in the same way that ordinary ridge regression (ORR is obtained from ordinary least squares (OLS. Properties of MUR are derived. Results on its matrix mean squared error (MMSE are obtained. MUR is compared with ORR and URR in terms of MMSE. These results are illustrated with an example based on data generated by Hoerl and Kennard (1975.

  4. Large fault fabric of the Ninetyeast Ridge implies near-spreading ridge formation

    Digital Repository Service at National Institute of Oceanography (India)

    Sager, W.W.; Paul, C.F; Krishna, K.S.; Pringle, M.S.; Eisin, A.E.; Frey, F; Rao, D; Levchenko, O.V.

    Large Fault Fabric of the Ninetyeast Ridge Implies Near-Spreading Ridge Formation 1 W. W. Sager 1 *, C. F. Paul 1 , K. S. Krishna 2 , M. Pringle 3 , A. E. Eisin 1,4 , F. A. Frey 3 , D. Gopala 2 Rao 5 , O. Levchenko 6 3 1 Department of Oceanography....proc.sr.121.122.1991. 254 Sandwell, D. T., and W. H. F. Smith (2009), Global marine gravity from retracked Geosat and 255 ERS-1 Altimetry: Ridge segmentation versus spreading rate, J. Geophys. Res., 114, 1-16, 256 doi:10.10029/2008JB006008, 2009. 257...

  5. Endodontic-related inferior alveolar nerve and mental foramen paresthesia.

    Science.gov (United States)

    Morse, D R

    1997-10-01

    Paresthesia is a condition that involves perverted sensations of pain, touch, or temperature. It has a variety of possible causes. This article presents a literature review and case reports of endodontically related inferior alveolar nerve and mental foramen paresthesia. Nondrug prevention methods and the dental uses of dexamethasone are also discussed.

  6. Pulmonary alveolar proteinosis in an indium-processing worker

    Institute of Scientific and Technical Information of China (English)

    XIAO Yong-long; CAI Hou-rong; WANG Yi-hua; MENG Fan-qing; ZHANG De-ping

    2010-01-01

    @@ With the increasing number of workers engaged in liquid-crystal displays (LCD) manufacturer, lung diseases related to this occupational exposure are attracting more attention.Herein we report a case of interstitial lung disease in a LCD processing worker, which was pathologically confirmed as pulmonary alveolar proteinosis (PAP).

  7. Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins

    NARCIS (Netherlands)

    Szafranski, P.; Gambin, T.; Dharmadhikari, A.V.; Akdemir, K.C.; Jhangiani, S.N.; Schuette, J.; Godiwala, N.; Yatsenko, S.A.; Sebastian, J.; Madan-Khetarpal, S.; Surti, U.; Abellar, R.G.; Bateman, D.A.; Wilson, A.L.; Markham, M.H.; Slamon, J.; Santos-Simarro, F.; Palomares, M.; Nevado, J.; Lapunzina, P.; Chung, B.H.; Wong, W.L.; Chu, Y.W.; Mok, G.T.; Kerem, E.; Reiter, J.; Ambalavanan, N.; Anderson, S.A.; Kelly, D.R.; Shieh, J.; Rosenthal, T.C.; Scheible, K.; Steiner, L.; Iqbal, M.A.; McKinnon, M.L.; Hamilton, S.J.; Schlade-Bartusiak, K.; English, D.; Hendson, G.; Roeder, E.R.; DeNapoli, T.S.; Littlejohn, R.O.; Wolff, D.J.; Wagner, C.L.; Yeung, A.; Francis, D.; Fiorino, E.K.; Edelman, M.; Fox, J.; Hayes, D.A.; Janssens, S.; Baere, E. De; Menten, B.; Loccufier, A.; Vanwalleghem, L.; Moerman, P.; Sznajer, Y.; Lay, A.S.; Kussmann, J.L.; Chawla, J.; Payton, D.J.; Phillips, G.E.; Brosens, E.; Tibboel, D.; Klein, A.; Maystadt, I.; Fisher, R.; Sebire, N.; Male, A.; Chopra, M.; Pinner, J.; Malcolm, G.; Peters, G.; Arbuckle, S.; Lees, M.; Mead, Z.; Quarrell, O.; Sayers, R.; Owens, M.; Shaw-Smith, C.; Lioy, J.; McKay, E.; Leeuw, N. de; Feenstra, I.; Spruijt, L.; Elmslie, F.; Thiruchelvam, T.; Bacino, C.A.; Langston, C.; Lupski, J.R.; Sen, P.; Popek, E.; Stankiewicz, P.

    2016-01-01

    Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) is a lethal lung developmental disorder caused by heterozygous point mutations or genomic deletion copy-number variants (CNVs) of FOXF1 or its upstream enhancer involving fetal lung-expressed long noncoding RNA genes LINC0108

  8. Granulocyte macrophage colony stimulating factor therapy for pulmonary alveolar proteinosis.

    Science.gov (United States)

    Shende, Ruchira P; Sampat, Bhavin K; Prabhudesai, Pralhad; Kulkarni, Satish

    2013-03-01

    We report a case of 58 year old female diagnosed with Pulmonary Alveolar Proteinosis (PAP) with recurrence of PAP after 5 repeated whole lung lavage, responding to subcutaneous injections of Granulocyte Macrophage Colony Stimulating Factor therapy (GM-CSF). Thus indicating that GM-CSF therapy is a promising alternative in those requiring repeated whole lung lavage

  9. Complications in alveolar distraction osteogenesis of the atrophic mandible.

    NARCIS (Netherlands)

    Perdijk, F.B.; Meijer, G.J.; Strijen, P.J.; Koole, R.

    2007-01-01

    To improve the starting point for placement of dental implants, 45 patients suffering from atrophied edentulous mandibles, with a vertical height varying between 7.3 and 15.8mm, were treated by alveolar vertical distraction osteogenesis (VDO). The mean follow-up period was 3 years, ranging from 1 to

  10. Complications in alveolar distraction osteogenesis of the atrophic mandible

    NARCIS (Netherlands)

    Perdijk, F. B. T.; van Strijen, P. J.; Meijer, G.

    2007-01-01

    To improve the starting point for placement of dental implants, 45 patients suffering from atrophied edentulous mandibles, with a vertical height varying between 7.3 and 15.8 turn, were treated by alveolar vertical distraction osteogenesis (VDO). The mean follow-up period was 3 years, ranging from 1

  11. Classification of Alveolar Bone Destruction Patterns on Maxillary ...

    African Journals Online (AJOL)

    2017-09-14

    Sep 14, 2017 ... The aim of this research was to classify alveolar bone defects in the ... 669 maxillary molars of 243 patients with periodontal bone loss were investigated on four aspects ...... about one-third (35.2%) of all defects.[28,29] Our ...

  12. Remodeling dynamics in the alveolar process in skeletally mature dogs.

    Science.gov (United States)

    Huja, Sarandeep S; Fernandez, Soledad A; Hill, Kara J; Li, Yan

    2006-12-01

    Bone turnover rates can be altered by metabolic and mechanical demands. Due to the difference in the pattern of loading, we hypothesized that there are differences in bone remodeling rates between the maxillary and mandibular alveolar processes. Furthermore, in a canine model, the alveolar process of teeth that lack contact (e.g., second premolars) would have a different turnover rate than bone supporting teeth with functional contact (e.g., first molars). Six skeletally mature male dogs were given a pair of calcein labels. After sacrifice, specimens representing the anterior and posterior locations of both jaws were prepared for examination by histomorphometric methods to evaluate the bone volume/total volume (BV/TV; %), bone volume (mm2), mineral apposition rate (MAR; microm/day), and bone formation rate (BFR; %/year) in the alveolar process. There were no significant differences (P>0.05) in the BV/TV within the jaws. The bone volume within the alveolar process of the mandible was 2.8-fold greater than in the maxilla. The MAR was not significantly different between the jaws and anteroposterior locations. However, the BFR was significantly (Parchitecture.

  13. An unusual delayed complication of inferior alveolar nerve block.

    Science.gov (United States)

    Smyth, Joanna; Marley, John

    2010-01-01

    Systemic and localised complications after administration of local anaesthetic for dental procedures are well recognised. We present two cases of patients with trismus and sensory deficit that arose during resolution of trismus as a delayed complication of inferior alveolar nerve block.

  14. Hyperpolarized Xe MR imaging of alveolar gas uptake in humans.

    Directory of Open Access Journals (Sweden)

    Zackary I Cleveland

    Full Text Available BACKGROUND: One of the central physiological functions of the lungs is to transfer inhaled gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar gas uptake provide only global information and thus lack the sensitivity and specificity needed to account for regional variations in gas exchange. METHODS AND PRINCIPAL FINDINGS: Here we exploit the solubility, high magnetic resonance (MR signal intensity, and large chemical shift of hyperpolarized (HP (129Xe to probe the regional uptake of alveolar gases by directly imaging HP (129Xe dissolved in the gas exchange tissues and pulmonary capillary blood of human subjects. The resulting single breath-hold, three-dimensional MR images are optimized using millisecond repetition times and high flip angle radio-frequency pulses, because the dissolved HP (129Xe magnetization is rapidly replenished by diffusive exchange with alveolar (129Xe. The dissolved HP (129Xe MR images display significant, directional heterogeneity, with increased signal intensity observed from the gravity-dependent portions of the lungs. CONCLUSIONS: The features observed in dissolved-phase (129Xe MR images are consistent with gravity-dependent lung deformation, which produces increased ventilation, reduced alveolar size (i.e., higher surface-to-volume ratios, higher tissue densities, and increased perfusion in the dependent portions of the lungs. Thus, these results suggest that dissolved HP (129Xe imaging reports on pulmonary function at a fundamental level.

  15. Alveolar echinococcosis localized in the liver, lung and brain

    Institute of Scientific and Technical Information of China (English)

    Seyit Mehmet Kayacan; Kutigin Turkmen; Fatih Yakar; Kerim Guier; Sezai Vatansever; Suleyman Temiz; Bora Uslu; Dilek Kayacan; Vakur Akkaya; Osman Erk; Büent Saka; Aytac Karadag

    2008-01-01

    @@ Echinococcosis is a parasitic disease caused by the larval forms of echinococci. It has two main forms as the unilocular cystic form that is more commonly seen and caused by E. granulosus and the alveolar form that is rarely seen and caused by E.

  16. An unusual, structurally preserved ovule from the Permian of Antarctica.

    Science.gov (United States)

    Klavins, S D.; Taylor, E L.; Krings, M; Taylor, T N.

    2001-06-01

    Anatomically preserved ovules are described from silicified peat of Late Permian age collected from Skaar Ridge in the central Transantarctic Mountains, Antarctica. The small ovules are significant in possessing fleshy apical appendages and a funnel-shaped micropylar extension formed by the sarcotestal layer of the integument, by which they differ from all other Permian ovules described to date. The apical modifications may have functioned in pollination and/or seed dispersal. Similarity with the apical organization of earlier Paleozoic ovules is shown to be superficial, since the analogous structures are developmentally derived from different tissues. Although the ovules occur in rocks in which glossopterids are the only gymnosperms represented, there is insufficient evidence to assign them to a taxonomic group. These ovules are of particular importance because there are so few anatomically preserved gymnosperm reproductive structures known from the Permian and thus provide new data on the diversity of late Paleozoic gymnosperms.

  17. "Recent" macrofossil remains from the Lomonosov Ridge, central Arctic Ocean

    Science.gov (United States)

    Le Duc, Cynthia; de Vernal, Anne; Archambault, Philippe; Brice, Camille; Roberge, Philippe

    2016-04-01

    The examination of surface sediment samples collected from 17 sites along the Lomonosov Ridge at water depths ranging from 737 to 3339 meters during Polarstern Expedition PS87 in 2014 (Stein, 2015), indicates a rich biogenic content almost exclusively dominated by calcareous remains. Amongst biogenic remains, microfossils (planktic and benthic foraminifers, pteropods, ostracods, etc.) dominate but millimetric to centrimetric macrofossils occurred frequently at the surface of the sediment. The macrofossil remains consist of a large variety of taxa, including gastropods, bivalvia, polychaete tubes, scaphopods, echinoderm plates and spines, and fish otoliths. Among the Bivalvia, the most abundant taxa are Portlandia arctica, Hyalopecten frigidus, Cuspidaria glacilis, Policordia densicostata, Bathyarca spp., and Yoldiella spp. Whereas a few specimens are well preserved and apparently pristine, most mollusk shells displayed extensive alteration features. Moreover, most shells were covered by millimeter scale tubes of the serpulid polychaete Spirorbis sp. suggesting transport from low intertidal or subtidal zone. Both the ecological affinity and known geographic distribution of identified bivalvia as named above support the hypothesis of transportation rather than local development. In addition to mollusk shells, more than a hundred fish otoliths were recovered in surface sediments. The otoliths mostly belong to the Gadidae family. Most of them are well preserved and without serpulid tubes attached to their surface, suggesting a local/regional origin, unlike the shell remains. Although recovered at the surface, the macrofaunal assemblages of the Lomonosov Ridge do not necessarily represent the "modern" environments as they may result from reworking and because their occurrence at the surface of the sediment may also be due to winnowing of finer particles. Although the shells were not dated, we suspect that their actual ages may range from modern to several thousands of

  18. Iapetus' Geophysics: Rotation Rate, Shape, and Equatorial Ridge

    Science.gov (United States)

    Castillo-Rogez, J. C.; Matson, D. L.; Sotin, C.; Johnson, T. V.; Lunine, J. I.; Thomas, P. C.

    2007-01-01

    Iapetus has preserved evidence that constrains the modeling of its geophysical history from the time of its accretion until now. The evidence is (a) its present 79.33-day rotation or spin rate, (b) its shape that corresponds to the equilibrium figure for a hydrostatic body rotating with a period of approximately 16 h, and (c) its high, equatorial ridge, which is unique in the Solar System. This paper reports the results of an investigation into the coupling between Iapetus' thermal and orbital evolution for a wide range of conditions including the spatial distributions with time of composition, porosity, short-lived radioactive isotopes (SLRI), and temperature. The thermal model uses conductive heat transfer with temperature-dependent conductivity. Only models with a thick lithosphere and an interior viscosity in the range of about the water ice melting point can explain the observed shape. Short-lived radioactive isotopes provide the heat needed to decrease porosity in Iapetus? early history. This increases thermal conductivity and allows the development of the strong lithosphere that is required to preserve the 16-h rotational shape and the high vertical relief of the topography. Long-lived radioactive isotopes and SLRI raise internal temperatures high enough that significant tidal dissipation can start, and despin Iapetus to synchronous rotation. This occurred several hundred million years after Iapetus formed. The models also constrain the time when Iapetus formed because the successful models are critically dependent upon having just the right amount of heat added by SLRI decay in this early period. The amount of heat available from short-lived radioactivity is not a free parameter but is fixed by the time when Iapetus accreted, by the canonical concentration of Al-26, and, to a lesser extent, by the concentration of Fe-60. The needed amount of heat is available only if Iapetus accreted between 2.5 and 5.0Myr after the formation of the calcium aluminum

  19. Remedial Investigation Work Plan for Chestnut Ridge Operable Unit 1 (Chestnut Ridge Security Pits) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    This Remedial Investigation (RI) Work Plan specifically addresses Chestnut Ridge Operable Unit 1, (OU1) which consists of the Chestnut Ridge Security Pits (CRSP). The CRSP are located {approximately}800 ft southeast of the central portion of the Y-12 Plant atop Chestnut Ridge, which is bounded to the northwest by Bear Creek Valley and to the southeast by Bethel Valley. Operated from 1973 to 1988, the CRSP consisted of a series of trenches used for the disposal of classified hazardous and nonhazardous waste materials. Disposal of hazardous waste materials was discontinued in December 1984, while nonhazardous waste disposal ended on November 8, 1988. An RI is being conducted at this site in response to CERCLA regulations. The overall objectives of the RI are to collect data necessary to evaluate the nature and extent of contaminants of concern (COC), support an ecological risk assessment (ERA) and a human health risk assessment (HHRA), support the evaluation of remedial alternatives, and ultimately develop a Record of Decision for the site. The purpose of this Work Plan is to outline RI activities necessary to define the nature and extent of suspected contaminants at Chestnut Ridge OU1. Potential migration pathways also will be investigated. Data collected during the RI will be used to evaluate the overall risk posed to human health and the environment by OU1.

  20. Mid-oceanic ridges - Guest editorial

    Digital Repository Service at National Institute of Oceanography (India)

    Banerjee, R.; Iyer, S.D.

    Ins titutes of Techno logy and national laboratories. A few Inter national re - searchers, notably from the USA, Portugal, France and J a pan too have shown interest in the I n Ridge and are keen to collaborate with India. It is foreseen that In...

  1. Petrography of basalts from the Carlsberg ridge

    Digital Repository Service at National Institute of Oceanography (India)

    Banerjee, R.; Iyer, S.D.

    Petrographic characteristics of basalts collected from a segment of the Carlsberg Ridge (lat. 3 degrees 35'N to 3 degrees 41'N; long. 64 degrees 05'E to 64 degrees 09'E) show typical pillow lava zonations with variable concentrations of plagioclase...

  2. Oak Ridge reservation land-use plan

    Energy Technology Data Exchange (ETDEWEB)

    Bibb, W. R.; Hardin, T. H.; Hawkins, C. C.; Johnson, W. A.; Peitzsch, F. C.; Scott, T. H.; Theisen, M. R.; Tuck, S. C.

    1980-03-01

    This study establishes a basis for long-range land-use planning to accommodate both present and projected DOE program requirements in Oak Ridge. In addition to technological requirements, this land-use plan incorporates in-depth ecological concepts that recognize multiple uses of land as a viable option. Neither environmental research nor technological operations need to be mutually exclusive in all instances. Unique biological areas, as well as rare and endangered species, need to be protected, and human and environmental health and safety must be maintained. The plan is based on the concept that the primary use of DOE land resources must be to implement the overall DOE mission in Oak Ridge. This document, along with the base map and overlay maps, provides a reasonably detailed description of the DOE Oak Ridge land resources and of the current and potential uses of the land. A description of the land characteristics, including geomorphology, agricultural productivity and soils, water courses, vegetation, and terrestrial and aquatic animal habitats, is presented to serve as a resource document. Essentially all DOE land in the Oak Ridge area is being fully used for ongoing DOE programs or has been set aside as protected areas.

  3. Ridges and hotspots: perspectives from global tomography

    OpenAIRE

    Zhang, Yu-Shen; Tanimoto, Toshiro

    1991-01-01

    Resolution in global tomography has improved to a level of about 1000 km due to a rapid increase of digital data during the last decade. We have started to see various important tectonic features in some detail. We will attempt to summarize our current observations for ridges and hotspots.

  4. 27 CFR 9.182 - Ribbon Ridge.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Ribbon Ridge. 9.182 Section 9.182 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT..., to the road's intersection with North Valley Road, near the Erwin Young School, section 39, T3S, R3W...

  5. Oak Ridge Reservation Waste Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Turner, J.W. [ed.

    1995-02-01

    This report presents the waste management plan for the Oak Ridge Reservation facilities. The primary purpose is to convey what facilities are being used to manage wastes, what forces are acting to change current waste management systems, and what plans are in store for the coming fiscal year.

  6. Structure and origin of the 85 degrees E ridge

    Digital Repository Service at National Institute of Oceanography (India)

    Ramana, M.V.; Subrahmanyam, V.; Chaubey, A.K.; Ramprasad, T.; Sarma, K.V.L.N.S.; Krishna, K.S.; Desa, M.; Murty, G.P.S.; Subrahmanyam, C.

    processes for the ridge emplacement have been suggested. Ridge emplacement may be (1) due to shearing of the lithosphere caused by stretching and compressional forces associated at the time of major plate reorganization immediately after the evolution...

  7. Wrinkle Ridges in Aeolis Dorsa, Mars: Preliminary Mapping

    Science.gov (United States)

    Borden, R. M.; Burr, D. M.

    2016-06-01

    Previous work has interpreted wrinkle ridges as compressional landforms caused by movement along blind thrust faults. Our preliminary mapping in the Aeolis Dorsa, Mars has identified widely distributed wrinkle ridges, suggesting episodic contraction.

  8. Prediction of eigenmodes cutoff frequencies of sectoral coaxial ridged waveguides

    OpenAIRE

    2012-01-01

    A mathematical model of sectoral coaxial ridged waveguides has been developed using coupled-integralequations technique. Maximal ratios of cutoff frequencies of two lowest modes of sectoral coaxial ridged waveguides have been obtained.

  9. Efficiency of local surface plasmon polariton excitation on ridges

    DEFF Research Database (Denmark)

    Radko, Ilya; Bozhevolnyi, Sergey I.; Boltasseva, Alexandra

    2008-01-01

    We investigate experimentally and numerically the efficiency of surface plasmon polariton excitation by a focused laser beam using gold ridges. The dependence of the efficiency on geometrical parameters of ridges and wavelength dependence are examined. The experimental measurements accomplished...

  10. Alveolar bone grafting with simultaneous cleft lip rhinoplasty.

    Science.gov (United States)

    Kim, Young-Eun; Han, Jihyeon; Baek, Rong-Min; Kim, Baek-Kyu

    2016-11-01

    Optimal timing for cleft lip rhinoplasty is controversial. Definitive rhinoplasty is deferred until facial skeletal growth is completed. Intermediate rhinoplasty is performed after stabilization of the grafted alveolar bone, because the grafted bone tends to be absorbed over several months postoperatively, distorting the nasal profile. Here, we report our experience with simultaneous rhinoplasty during alveolar bone grafting for indicated patients, describe our surgical technique that ensures long-term bone graft survival, and report graft take rates and nasal profile changes. This retrospective chart review included a total of 54 patients; 44 underwent alveolar bone grafting only, and 10 underwent simultaneous cleft lip rhinoplasty. All surgeries were conducted with a judicious mucosal incision for tensionless wound closure. Bone graft take was evaluated with dental radiographs by the Bergland classification. Further, nasal aesthetic outcome was evaluated with medical photographs, based on nostril height and width and alar base width. In total, 96.3% of clefts showed graft success with Type I (66.7%) or Type II (27.8%) classifications; only 3.7% of clefts showed unfavorable results classified as Type III, and no clefts showed Type IV failure. The nasal shape was flatter with a decreased nostril height and increased nostril width after alveolar bone grafting, while nostril height was increased and nostril width was decreased in patients who underwent simultaneous rhinoplasty. With surgical techniques ensuring alveolar bone graft survival, simultaneous cleft lip rhinoplasty can result in nasal aesthetic improvement for patients with severe nasal deformities, decreasing the number of operations. Copyright © 2016 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  11. Alveolar bone measurement precision for phosphor-plate images

    Science.gov (United States)

    HILDEBOLT, CHARLES F.; COUTURE, REX; GARCIA, NATHALIA M.; DIXON, DEBRA; SHANNON, WILLIAM DOUGLAS; LANGENWALTER, ERIC; CIVITELLI, ROBERTO

    2009-01-01

    Objectives To demonstrate methods for determining measurement precision and to determine the precision of alveolar-bone measurements made with a vacuum-coupled, positioning device and phosphor-plate images. Study design Subjects were rigidly attached to the x-ray tube by means of a vacuum coupling device and custom, cross-arch, bite plates. Original and repeat radiographs (taken within minutes of each other) were obtained of the mandibular posterior teeth of 51 subjects, and cementoenamel-junction-alveolar-crest (CEJ-AC) distances were measured on both sets of images. In addition, x-ray-transmission (radiodensity) and alveolar-crest-height differences were determined by subtracting one image from the other. Image subtractions and measurements were performed twice. Based on duplicate measurements, the root-mean-square standard deviation (precision) and least-significant change (LSC) were calculated. LSC is the magnitude of change in a measurement needed to indicate that a true biological change has occurred. Results The LSCs were 4% for x-ray transmission, 0.49 mm for CEJ-AC distance, and 0.06 mm for crest-height 0.06 mm. Conclusion The LSCs for our CEJ-AC and x-ray transmission measurements are similar to what has been reported. The LSC for alveolar-crest height (determined with image subtraction) was less than 0.1 mm. Compared with findings from previous studies, this represents a highly precise measurement of alveolar crest height. The methods demonstrated for calculating LSC can be used by investigators to determine how large changes in radiographic measurements need to be before the changes can be considered (with 95% confidence) true biological changes and not noise (that is, equipment/observer error). PMID:19716499

  12. Stress area of the mandibular alveolar mucosa under complete denture with linear occlusion at lateral excursion

    Institute of Scientific and Technical Information of China (English)

    LU Ya-lin; LOU Hang-di; RONG Qi-guo; DONG Jian; XU Jun

    2010-01-01

    Background The rocking and instability of a loaded complete denture (CD) during lateral excursion reduce the bearing area under the denture base, causing localized high stress concentrations. This can lead to mucosal tenderness, ulceration, and alveolar bone resorption, and the linear occlusion design was to decrease the lateral force exerted on the denture and to ensure denture stability. But it is not known how the bearing areas of linear occlusal CDs (LOCDs) and anatomic occlusal CDs (AOCDs) differ. The purpose of this study was to analyze and compare the distributions of the high and low vertical stress-bearing areas in the mandibular alveolar mucosa under LOCDs and AOCDs at lateral excursion.Methods Computerized tomography (CT) and finite element analysis were used to establish three-dimensional models of an edentulous maxilla and mandible with severe residual ridge resorption. These models were composed of maxillary and mandibular bone structure, mucosa, and the LOCD or AOCD. Lateral excursion movements of the mandible were simulated and the vertical stress-bearing areas in the mucosa under both mandibular CDs were analyzed using ANSYS 7.0.Results On the working side, the high stress-bearing (-0.07 to -0.1 Mpa) area under the LOCD during lateral excursion was smaller than that under the AOCD, while the medium stress-bearing (-0.03 to -0.07 Mpa) area under the LOCD was 1.33-fold that under the AOCD. The medium stress-bearing area on the non-working side under the LOCD was 2.4-fold that under the AOCD. Therefore, the overall medium vertical stress-bearing area under the LOCD was 20% larger than that under the AOCD.Conclusions During lateral excursion, the medium vertical stress-bearing area under a mandibular LOCD was larger and the high vertical stress-bearing area was smaller than that under an AOCD. Thus, the vertical stress under the LOCD was distributed more evenly and over a wider area than that under the AOCD, thereby improving denture stability.

  13. Distracción osteogénica alveolar como método de aumento del reborde alveolar

    Directory of Open Access Journals (Sweden)

    Denia Morales Navarro

    2011-03-01

    Full Text Available La distracción osteogénica alveolar, como proceso biológico de neoformación de hueso alveolar, nos motivó a la realización de la presente revisión bibliográfica, con el objetivo enfatizar en el análisis de las variables: antecedentes históricos en Cuba, clasificación de los distractores, fases de la distracción (latencia, distracción y consolidación, indicaciones, contraindicaciones, ventajas, desventajas y complicaciones. Se realizó una revisión bibliográfica mediante la consulta de bases de datos de los sistemas referativos, como MEDLINE y PubMed con la utilización de descriptores "alveolar distraction" y "osteogenic distraction". Se consultaron las fuentes bibliográficas publicadas fundamentalmente en los últimos 5 años, lo que reveló que esta técnica es una excelente alternativa para la formación de huesos y tejidos blandos en zonas de atrofia alveolar, que consta de tres etapas: latencia, distracción y consolidación; un método previsible y con bajas tasas de reabsorción ósea en comparación con otras técnicas de aumento del reborde alveolar. Tiene su principal indicación en la terapia de implantes al proveer volumen óseo. Debemos individualizar cada caso y usar el método más adecuado según las características clínicas y personales del paciente. Una adecuada selección de los casos y una mejor comprensión de la técnica son los puntales para lograr exitosos resultados mediante la distracción osteogénica alveolar. En Cuba se ha aplicado poco la distracción alveolar, por lo que ha sido necesario ampliar los estudios sobre esta temática.

  14. Seismic hazard evaluation for Department of Energy Oak Ridge Reservations, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    McGuire, R.K.; Toro, G.F. [Risk Engineering, Inc., Golden, CO (United States); Hunt, R.J. [Martin Marietta Energy Systems, Inc., Oak Ridge, TN (United States). Center for Natural Phenomena Engineering

    1992-09-30

    This study presents the results of an investigation of seismic hazard at the Department of Energy Oak Ridge Reservations (K-25 Site, Oak Ridge National Laboratories, and Oak Ridge Y-12 Plant), located in Oak Ridge, Tennessee. Oak Ridge is located in eastern Tennessee, in an area of moderate to high historical seismicity. Results from two separate seismic hazard analyses are presented. The EPRI/SOG analysis uses the input data and methodology developed by the Electric Power Research Institute, under the sponsorship of several electric utilities, for the evaluation of seismic hazard in the central and eastern United States. The LLNL analysis uses the input data and methodology developed by the Lawrence Livermore National Laboratory for the Nuclear Regulatory Commission. Both the EPRI/SOG and LLNL studies characterize earth-science uncertainty on the causes and characteristics of earthquakes in the central and eastern United States. This is accomplished by considering multiple hypotheses on the locations and parameters of seismic source zones and by considering multiple attenuation functions for the prediction of ground shaking given earthquake size and location. These hypotheses were generated by multiple expert teams and experts. Furthermore, each team and expert was asked to generate multiple hypotheses in order to characterize his own internal uncertainty. The seismic-hazard calculations are performed for all hypotheses. Combining the results from each hypothesis with the weight associated to that hypothesis, one obtains an overall representation of the seismic hazard at the Oak Ridge site and its uncertainty.

  15. MAPK-Mediated YAP Activation Controls Mechanical-Tension-Induced Pulmonary Alveolar Regeneration

    Directory of Open Access Journals (Sweden)

    Zhe Liu

    2016-08-01

    Full Text Available The pulmonary alveolar epithelium undergoes extensive regeneration in response to lung injuries, including lung resection. In recent years, our understanding of cell lineage relationships in the pulmonary alveolar epithelium has improved significantly. However, the molecular and cellular mechanisms that regulate pneumonectomy (PNX-induced alveolar regeneration remain largely unknown. In this study, we demonstrate that mechanical-tension-induced YAP activation in alveolar stem cells plays a major role in promoting post-PNX alveolar regeneration. Our results indicate that JNK and p38 MAPK signaling is critical for mediating actin-cytoskeleton-remodeling-induced nuclear YAP expression in alveolar stem cells. Moreover, we show that Cdc42-controlled actin remodeling is required for the activation of JNK, p38, and YAP in post-PNX lungs. Our findings together establish that the Cdc42/F-actin/MAPK/YAP signaling cascade is essential for promoting alveolar regeneration in response to mechanical tension in the lung.

  16. Westward migration of oceanic ridges and related asymmetric upper mantle differentiation

    Science.gov (United States)

    Chalot-Prat, Françoise; Doglioni, Carlo; Falloon, Trevor

    2017-01-01

    Combining geophysical, petrological and structural data on oceanic mantle lithosphere, underlying asthenosphere and oceanic basalts, an alternative oceanic plate spreading model is proposed in the framework of the westward migration of oceanic spreading ridges relative to the underlying asthenosphere. This model suggests that evolution of both the composition and internal structure of oceanic plates and underlying upper mantle strongly depends at all scales on plate kinematics. We show that the asymmetric features of lithospheric plates and underlying upper asthenosphere on both sides of oceanic spreading ridges, as shown by geophysical data (seismic velocities, density, thickness, and plate geometry), reflect somewhat different mantle compositions, themselves related to various mantle differentiation processes (incipient to high partial melting degree, percolation/reaction and refertilization) at different depths (down to 300 km) below and laterally to the ridge axis. The fundamental difference between western and eastern plates is linked to the westward ridge migration inducing continuing mantle refertilization of the western plate by percolation-reaction with ascending melts, whereas the eastern plate preserves a barely refertilized harzburgitic residue. Plate thickness on both sides of the ridge is controlled both by cooling of the asthenospheric residue and by the instability of pargasitic amphibole producing a sharp depression in the mantle solidus as it changes from vapour-undersaturated to vapour-saturated conditions, its intersection with the geotherm at 90 km, and incipient melt production right underneath the lithosphere-asthenosphere boundary (LAB). Thus the intersection of the geotherm with the vapour-saturated lherzolite solidus explains the existence of a low-velocity zone (LVZ). As oceanic lithosphere is moving westward relative to asthenospheric mantle, this partially molten upper asthenosphere facilitates the decoupling between lower asthenosphere

  17. Characteristic aspects of alveolar proteinosis diagnosis Aspectos característicos do diagnóstico da proteinose alveolar

    Directory of Open Access Journals (Sweden)

    Thiago Prudente Bártholo

    2012-02-01

    Full Text Available Alveolar proteinosis is an uncommon pulmonary disease characterized by an accumulation of surfactant in terminal airway and alveoli, thereby impairing gas exchange and engendering respiratory insufficiency in some cases. Three clinically and etiologically distinct forms of pulmonary alveolar proteinosis are recognized: congenital, secondary and idiopathic, the latter corresponding to 90% of the cases. In this case report we present a young male patient that was diagnosed with alveolar proteinosis. Computed tomography of the thorax, bronchoscopy and transbronchial biopsy were performed. The histopathologic aspect was characteristic. The patient was discharged in good health conditions and remains asymptomatic to date.Proteinose alveolar é uma doença pulmonar incomum caracterizada pelo acúmulo de surfactante nas vias aéreas terminais e nos alvéolos, alterando a troca gasosa e, em alguns casos, promovendo insuficiência respiratória. Três formas clínicas e etiologicamente distintas de proteinose alveolar são reconhecidas: congênitas, secundárias e idiopáticas (mais de 90% dos casos são de etiologia idiopática. Neste relato, apresentamos um homem jovem que foi diagnosticado com proteinose pulmonar. Tomografia computadorizada de tórax, broncoscopia e biópsia transbrônquica foram realizadas. O aspecto histopatológico foi característico. O paciente teve alta, com boas condições de saúde, e encontra-se assintomático nos dias de hoje.

  18. The role of probiotic on alveolar bone resorption

    Directory of Open Access Journals (Sweden)

    Desi Sandra Sari

    2011-09-01

    Full Text Available Background: Probiotics are microbes derived from the group of lactic acid bacteria that work to maintain the health of hosts. Probiotics can also be used to improve oral health. Periodontal disease is usually marked with gingival inflammation and alveolar bone resorption. Gram negative anaerobic bacteria that play important role in human periodontal disease are Porphyromonas gingivalis. (P. gingivalis. P. gingivalis is a virulent bacteria in vivo or in vitro, and mostly found in subgingival plaque of periodontitis patients. Purpose: This study is aimed to know the role of probiotics to inhibit the resorption of alveolar bone induced with P. gingivalis. Methods: This study used male wistar rats divided into 4 groups. Group I was control group (without treatment; group II was induced with P. gingivalis ATCC 33277 for 5 days; group III was induced with P. gingivalis ATCC 33277 and also injected with probiotics (Lactobacillus casei ATCC 4224 for 5 days simultaneously; and group IV was induced with P. gingivalis ATCC 33277 for 5 days and also injected by probiotics (Lactobacillus casei ATCC 4224 in the next 5 days. After that, the samples were decapitated, taken their alveolar bone, and then were examined by immunohistochemistry to observe osteoclast activity in alveolar bone resorption by using tartrate-resistant acid phosphatase (TRAP expression. All data were then analyzed statistically. Results: It is known that there were significant differences of TRAP expression among all those treatment groups (p < 0.05. Conclusion: It then can be concluded that probiotics can decrease osteoclast activity in periodontal tissue of wistar rats, so it can inhibit alveolar bone resorption.Latar belakang: Probiotik adalah mikroba dari golongan bakteri asam laktat yang bekerja mempertahankan kesehatan host dan probiotik dapat digunakan untuk meningkatkan kesehatan rongga mulut. Penyakit periodontal ditandai dengan adanya keradangan pada gingiva dan resobsi tulang

  19. The first well-preserved coelophysoid theropod dinosaur from Asia.

    Science.gov (United States)

    You, Hai-Lu; Azuma, Yoichi; Wang, Tao; Wang, Ya-Ming; Dong, Zhi-Ming

    2014-10-16

    Coelophysoid dinosaurs represent the earliest major radiation of neotheropods. These small-to-medium-sized agile bipeds lived throughout much of Pangaea during the Late Triassic-arly Jurassic. Previously reported coelophysoid material from Asia (excluding the Gondwanan territory of India) is limited to two specimens that comprise only limb fragments. This paper describes a new genus and species of coelophysoid, Panguraptor lufengensis, from the Lower Jurassic Lufeng Formation of Yunnan Province, China. The new taxon is represented by a well-preserved skeleton, including the skull and lower jaw, the presacral vertebral column and partial ribs, the right scapula, a partial forelimb, part of the pelvic girdle, and an almost complete hind limb. It is distinguished from other coelophysoid theropods by the unique combination of the following three character states: 1) diagonal (rostrodorsal-caudoventral) ridge on lateral surface of maxilla, within antorbital fossa, 2) elliptical, laterally facing fenestra caudodorsal to aforementioned diagonal ridge, and 3) hooked craniomedial corner of distal tarsal IV. Cladistic analysis recovers Panguraptor lufengensis deeply nested within Coelophysoidea as a member of Coelophysidae, and it is more closely related to Coelophysis than to "Syntarsus". Panguraptor represents the first well-preserved coelophysoid theropod dinosaur from Asia, and provides fresh evidence supporting the hypothesis that terrestrial tetrapods tended to be distributed pan-continentally during the Early Jurassic.

  20. Peptide-induced de novo bone formation after tooth extraction prevents alveolar bone loss in a murine tooth extraction model.

    Science.gov (United States)

    Arai, Yuki; Aoki, Kazuhiro; Shimizu, Yasuhiro; Tabata, Yasuhiko; Ono, Takashi; Murali, Ramachandran; Mise-Omata, Setsuko; Wakabayashi, Noriyuki

    2016-07-05

    Tooth extraction causes bone resorption of the alveolar bone volume. Although recombinant human bone morphogenetic protein 2 (rhBMP-2) markedly promotes de novo bone formation after tooth extraction, the application of high-dose rhBMP-2 may induce side effects, such as swelling, seroma, and an increased cancer risk. Therefore, reduction of the necessary dose of rhBMP-2 which can still obtain sufficient bone mass is necessary by developing a new osteogenic reagent. Recently, we showed that the systemic administration of OP3-4 peptide, which was originally designed as a bone resorption inhibitor, had osteogenic ability both in vitro and in vivo. This study evaluated the ability of the local application of OP3-4 peptide to promote bone formation in a murine tooth extraction model with a very low-dose of BMP. The mandibular incisor was extracted from 10-week-old C57BL6/J male mice and a gelatin hydrogel containing rhBMP-2 with or without OP3-4 peptide (BMP/OP3-4) was applied to the socket of the incisor. Bone formation inside the socket was examined radiologically and histologically at 21 days after the extraction. The BMP/OP3-4-group showed significant bone formation inside the mandibular extraction socket compared to the gelatin-hydrogel-carrier-control group or rhBMP-2-applied group. The BMP/OP3-4-applied mice showed a lower reduction of alveolar bone and fewer osteoclast numbers, suggesting that the newly formed bone inside the socket may prevent resorption of the cortical bone around the extraction socket. Our data revealed that OP3-4 peptide promotes BMP-mediated bone formation inside the extraction socket of mandibular bone, resulting in preservation from the loss of alveolar bone.

  1. Preserving reptiles for research

    Science.gov (United States)

    Gotte, Steve W.; Jacobs, Jeremy F.; Zug, George R.; Dodd, C. Kenneth

    2016-01-01

    What are voucher specimens and why do we collect them? Voucher specimens are animals and/or their parts that are deposited in a research museum to document the occurrence of a taxon at a specific location in space and time (Pleijel et al., 2008; Reynolds and McDiarmid, 2012). For field biologists, vouchers are the repeatable element of a field study as they allow other biologists, now and in the future, to confirm the identity of species that were studied. The scientific importance of a voucher specimen or series of specimens is that other people are afforded the opportunity to examine the entire animal and confirm or correct identifications. A photographic record is somewhat useful for recording the occurrence of a species, but such records can be insufficient for reliable confirmation of specific identity. Even if a photo shows diagnostic characters of currently recognized taxa, it may not show characters that separate taxa that may be described in the future. Substantial cryptic biodiversity is being found in even relatively well-known herpetofaunas (Crawford et al., 2010), and specimens allow researchers to retroactively evaluate the true diversity in a study as understanding of taxonomy evolves. They enable biologists to study the systematic relationships of populations by quantifying variation in different traits. Specimens are also a source of biological data such as behaviour, ecology, epidemiology, and reproduction through examination of their anatomy, reproductive and digestive tracts, and parasites (Suarez and Tsutsui, 2004). Preserving reptiles as vouchers is not difficult, although doing it properly requires care, effort, and time. Poorly preserved vouchers can invalidate the results and conclusions of your study because of the inability to confirm the identity of your study animals. Good science requires repeatability of observations, and the absence of vouchers or poorly preserved ones prevents such confirmation. Due to space restrictions, we are

  2. Divergent Ridge Features on the Juan de Fuca and Gorda Ridges

    Science.gov (United States)

    Eaton, M. E.; Sautter, L.; Steele, M.

    2014-12-01

    Multibeam data collected using a Kongsberg EM122 sonar system on the NOAA ship R/V Marcus G. Langseth led by chief scientist Douglas Toomey (University of Oregon) in 2009 and with a Simrad EM302 sonar system on two NOAA ship Okeanos Explorer cruises led by chief scientists James Gardner (University of New Hampshire) and Catalina Martinez (University of Rhode Island) in 2009 show the morphology of the Juan de Fuca and Gorda Ridges, as well as the Blanco and Mendocino Fracture Zones. These ridges and fracture zones comprise the divergent plate boundary of the eastern edge of the Pacific Plate and the western edges of the Juan de Fuca and Gorda Plates. Both plates are being subducted beneath the western edge of the North American Plate. CARIS HIPS 8.1 software was used to process the multibeam data and create bathymetric images. The ridge axes, located off the coast of Washington and Oregon (USA) adjacent to the Cascadia Basin, indicate obvious signs of spreading, due to the series of faults and rocky ridges aligned parallel to the plate boundaries. Fault and ridge orientations are used to compare the direction of seafloor spreading, and indicate that both the Juan de Fuca Plate and Gorda Plate are spreading in a southeastern direction. Younger ridges from the Gorda Ridge system mapped in the study run parallel to the boundary, however older ridges do not show the same orientation, indicating a change in spreading direction. The presence of hydrothermal vents along the Juan de Fuca Ridge is also evidence of the active boundary, as the vent chimneys are composed of minerals and metals precipitated from the hot water heated by magma from beneath the spreading seafloor. In this study, the data are used to compare and contrast earthquake seismicity and ridge morphologies at a depth range of approximately 762 to 2134 meters. The diverging Pacific, Juan de Fuca, and Gorda Plates along with the San Andreas Fault have potential to increase seismic and volcanic activity around

  3. Preservation of micro-architecture and angiogenic potential in a pulmonary acellular matrix obtained using intermittent intra-tracheal flow of detergent enzymatic treatment

    Science.gov (United States)

    Maghsoudlou, Panagiotis; Georgiades, Fanourios; Tyraskis, Athanasios; Totonelli, Giorgia; Loukogeorgakis, Stavros P.; Orlando, Giuseppe; Shangaris, Panicos; Lange, Peggy; Delalande, Jean-Marie; Burns, Alan J.; Cenedese, Angelo; Sebire, Neil J.; Turmaine, Mark; Guest, Brogan N.; Alcorn, John F.; Atala, Anthony; Birchall, Martin A.; Elliott, Martin J.; Eaton, Simon; Pierro, Agostino; Gilbert, Thomas W.; De Coppi, Paolo

    2013-01-01

    Tissue engineering of autologous lung tissue aims to become a therapeutic alternative to transplantation. Efforts published so far in creating scaffolds have used harsh decellularization techniques that damage the extracellular matrix (ECM), deplete its components and take up to 5 weeks to perform. The aim of this study was to create a lung natural acellular scaffold using a method that will reduce the time of production and better preserve scaffold architecture and ECM components. Decellularization of rat lungs via the intratracheal route removed most of the nuclear material when compared to the other entry points. An intermittent inflation approach that mimics lung respiration yielded an acellular scaffold in a shorter time with an improved preservation of pulmonary micro-architecture. Electron microscopy demonstrated the maintenance of an intact alveolar network, with no evidence of collapse or tearing. Pulsatile dye injection via the vasculature indicated an intact capillary network in the scaffold. Morphometry analysis demonstrated a significant increase in alveolar fractional volume, with alveolar size analysis confirming that alveolar dimensions were maintained. Biomechanical testing of the scaffolds indicated an increase in resistance and elastance when compared to fresh lungs. Staining and quantification for ECM components showed a presence of collagen, elastin, GAG and laminin. The intratracheal intermittent decellularization methodology could be translated to sheep lungs, demonstrating a preservation of ECM components, alveolar and vascular architecture. Decellularization treatment and methodology preserves lung architecture and ECM whilst reducing the production time to 3 h. Cell seeding and in vivo experiments are necessary to proceed towards clinical translation. PMID:23727263

  4. A visual basic program for ridge axis picking on DEM data using the profile-recognition and polygon-breaking algorithm

    Science.gov (United States)

    Chang, Yet-Chung; Sinha, Gaurav

    2007-02-01

    For many scientists working with digital topographic data, extracting lineaments or linear features is an important step in structuring and analyzing raw data. A ridge axis, which represents the top a mountain ridge, is one of the most important topographic features used in a wide variety of applications. Algorithms and software for automating the extraction of ridges or ridge axes from DEMs are, however, still not easily available or not widely acceptable. In this paper, we present a user-friendly Visual Basic program that automates the extraction of the ridge axis system from DEM data, based on the profile-recognition and polygon-breaking algorithm (PPA). An important feature of PPA is that it takes a global approach, as opposed to the local neighborhood operators used in many other algorithms. Each segment detected by PPA considers not only relations with contiguous neighboring grid points, but also strives to preserve the continuity of the global trend. This is an attempt to simulate human operators, who always factor in the overall trend of the lineament before delineating its local parts. PPA starts by connecting all points in a neighborhood that can possibly lie on the ridge axis, thus forming a belt of polygons in the first step. Next, a polygon breaking process eliminates unwanted segments according to the assumption that a ridge segment cannot be the side of any closed polygon, and that the result should be a purely dendritic line pattern. Finally, a branch-reduction process is executed to eliminate all parallel false ridges that remained due to the conservative approach taken in the first step. Results indicate that PPA is reasonably successful in picking out ridges that would have been identified manually by experts. In addition to providing a detailed user interface for executing PPA, several modifications were made to significantly improve the computational efficiency of PPA, as compared to the original version published in 1998. The source codes are

  5. The Usumacinta–Grijalva beach-ridge plain in southern Mexico: a high-resolution archive of river discharge and precipitation

    Directory of Open Access Journals (Sweden)

    K. Nooren

    2017-09-01

    Full Text Available The beach-ridge sequence of the Usumacinta–Grijalva delta borders a 300 km long section of the southern Gulf of Mexico coast. With around 500 beach ridges formed in the last 6500 years, the sequence is unsurpassed in the world in terms of numbers of individual ridges preserved, continuity of the record, and temporal resolution. We mapped and dated the most extensively accreted part of the sequence, linking six phases of accretion to river mouth reconfigurations and constraining their ages with 14C and OSL dating. The geomorphological and sedimentological reconstruction relied on lidar data, coring transects, GPR measurements, grain-size analyses, and chemical fingerprinting of volcanic glass and pumice encountered within the beach and dune deposits. We demonstrate that the beach-ridge complex was formed under ample long-term fluvial sediment supply and shorter-term wave- and aeolian-modulated sediment reworking. The abundance of fluvially supplied sand is explained by the presence of easily weatherable Los Chocoyos ignimbrites from the ca. 84 ka eruption of the Atitlán volcano (Guatemala in the catchment of the Usumacinta River. Autocyclic processes seem responsible for the formation of ridge–swale couplets. Fluctuations in their periodicity (ranging from 6–19 years are governed by progradation rate, and are therefore not indicative of sea level fluctuations or variability in storm activity. The fine sandy beach ridges are mainly swash built. Ridge elevation, however, is strongly influenced by aeolian accretion during the time the ridge is located next to the beach. Beach-ridge elevation is negatively correlated with progradation rate, which we relate to the variability in sediment supply to the coastal zone, reflecting decadal-scale precipitation changes within the river catchment. In the southern Mexican delta plain, the coastal beach ridges therefore appear to be excellent recorders of hinterland precipitation.

  6. Antarctic science preserve polluted

    Science.gov (United States)

    Simarski, Lynn Teo

    Geophysicists are alarmed at the electromagnetic pollution of a research site in the Antarctic specifically set aside to study the ionosphere and magnetosphere. A private New Zealand communications company called Telecom recently constructed a satellite ground station within the boundaries of this Site of Special Scientific Interest (SSSI), protected since the mid-1970s. The placement of a commercial facility within this site sets an ominous precedent not only for the sanctity of other SSSIs, but also for Specially Protected Areas—preserves not even open to scientific research, such as certain penguin rookeries.The roughly rectangular, one-by-one-half mile site, located at Arrival Heights not far from McMurdo Station, is one of a number of areas protected under the Antarctic treaty for designated scientific activities. Many sites are set aside for geological or biological research, but this is the only one specifically for physical science.

  7. PRESERVING A TRADITION

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    COVER STORY The Chinese art of paper cutting has long been a popular pastime in the country’s rural areas.For more than 1,000 years,farming families have used it as a method for decorating their homes,but the tradition has struggled for survival in recent years.In Yanchuan County in China’s northwestern Shaanxi Province,however,the art form has experienced a revival thanks to the efforts of a local woman.Paper cutting master Gao Fenglian has invested her own money in establishing a paper cutting gallery in the region.The craft’s growing popularity has also fuelled a new wave of people wanting to learn how to cut.More than 10,000 of the county’s 200,000 are now skilled in the ancient craft,and its revival could serve as a model for the preservation of other Chinese traditions.

  8. Seismic Fault Preserving Diffusion

    CERN Document Server

    Lavialle, Olivier; Germain, Christian; Donias, Marc; Guillon, Sebastien; Keskes, Naamen; Berthoumieu, Yannick

    2007-01-01

    This paper focuses on the denoising and enhancing of 3-D reflection seismic data. We propose a pre-processing step based on a non linear diffusion filtering leading to a better detection of seismic faults. The non linear diffusion approaches are based on the definition of a partial differential equation that allows us to simplify the images without blurring relevant details or discontinuities. Computing the structure tensor which provides information on the local orientation of the geological layers, we propose to drive the diffusion along these layers using a new approach called SFPD (Seismic Fault Preserving Diffusion). In SFPD, the eigenvalues of the tensor are fixed according to a confidence measure that takes into account the regularity of the local seismic structure. Results on both synthesized and real 3-D blocks show the efficiency of the proposed approach.

  9. Seismic fault preserving diffusion

    Science.gov (United States)

    Lavialle, Olivier; Pop, Sorin; Germain, Christian; Donias, Marc; Guillon, Sebastien; Keskes, Naamen; Berthoumieu, Yannick

    2007-02-01

    This paper focuses on the denoising and enhancing of 3-D reflection seismic data. We propose a pre-processing step based on a non-linear diffusion filtering leading to a better detection of seismic faults. The non-linear diffusion approaches are based on the definition of a partial differential equation that allows us to simplify the images without blurring relevant details or discontinuities. Computing the structure tensor which provides information on the local orientation of the geological layers, we propose to drive the diffusion along these layers using a new approach called SFPD (Seismic Fault Preserving Diffusion). In SFPD, the eigenvalues of the tensor are fixed according to a confidence measure that takes into account the regularity of the local seismic structure. Results on both synthesized and real 3-D blocks show the efficiency of the proposed approach.

  10. Preservation of Built Environments

    DEFF Research Database (Denmark)

    Pilegaard, Marie Kirstine

    When built environments and recently also cultural environments are to be preserved, the historic and architectural values are identified as the key motivations. In Denmark the SAVE system is used as a tool to identify architectural values, but in recent years it has been criticized for having...... a too narrow aesthetic goal, especially when it comes to the evaluation of built environments as a whole. Architectural value has therefore been perceived as a different concept than aesthetic value, primarily related to a static and unchanging expression. This fact creates problems in relation...... to current conservation tasks, which today include more and more untraditionally built environments, including cultural environments. Architectural value must in this case rather be associated with development, ongoing processes, and allow room for future change. The Danish architect Johannes Exner, defines...

  11. Effect of Micro Ridges on Orientation of Cultured Cell

    Directory of Open Access Journals (Sweden)

    Haruka Hino

    2014-06-01

    Full Text Available The effect of micro ridges on orientation of cultured cells has been studied in vitro. Several patterns of micro ridges have been fabricated on a transparent polydimethylsiloxane disk with the photo lithography technique. The ridges consist of several lines of rectangular column: the width of 0.003 mm, the interval of 0.007 mm. Variation has been made on the height of the ridge between 0.0003 mm and 0.0035 mm. C2C12 (mouse myoblast cell line originated with cross-striated muscle of C3H mouse was cultured on the disk with the micro ridges for one week and was observed with an inverted phase contrast microscope. The experimental results show that cells adhere on the top of the ridge and align to the longitudinal direction of the micro ridges with the height between 0.0015 mm and 0.0025 mm.

  12. Active convection beneath ridges: a new spin

    Science.gov (United States)

    Katz, R. F.

    2009-12-01

    The role of buoyancy-driven, "active" upwelling beneath mid-ocean ridges has been long debated [1,2,3], with the naysayers holding sway in recent years. Recent work on tomographic imaging of the sub-ridge mantle has revealed patterns in velocity variation that seem inconsistent with what we expect of passive upwelling and melting [4]. The irregular distribution, asymmetry, and off-axis locations of slow regions in tomographic results are suggestive of time-dependent convective flow. Using 2D numerical simulations of internally consistent mantle and magmatic flow plus melting/freezing [5,6], I investigate the parametric subspace in which active convection is expected to occur. For low mantle viscosities, interesting symmetry-breaking behavior is predicted. References: [1] Rabinowicz, et al., EPSL, 1984; [2] Buck & Su, GRL, 1989; [3] Scott & Stevenson, JGR, 1989; [4] Toomey et al., Nature, 2007; [5] McKenzie, J.Pet., 1984; [6] Katz, J.Pet., 2008;

  13. Tubular initial conditions and ridge formation

    CERN Document Server

    Borysova, M S; Karpenko, Iu A; Shapoval, V M; Sinyukov, Yu M

    2013-01-01

    The 2D azimuth & rapidity structure of the two-particle correlations in relativistic A+A collisions is altered significantly by the presence of sharp inhomogeneities in superdense matter formed in such processes. The causality constraints enforce one to associate the long-range longitudinal correlations observed in a narrow angular interval, the so-called (soft) ridge, with peculiarities of the initial conditions of collision process. This study's objective is to analyze whether multiform initial tubular structures, undergoing the subsequent hydrodynamic evolution and gradual decoupling, can form the soft ridges. Motivated by the flux-tube scenarios, the initial energy density distribution contains the different numbers of high density tube-like boost-invariant inclusions that form a bumpy structure in the transverse plane. The influence of various structures of such initial conditions in the most central A+A events on the collective evolution of matter, resulting spectra, angular particle correlations an...

  14. Model selection in kernel ridge regression

    DEFF Research Database (Denmark)

    Exterkate, Peter

    2013-01-01

    Kernel ridge regression is a technique to perform ridge regression with a potentially infinite number of nonlinear transformations of the independent variables as regressors. This method is gaining popularity as a data-rich nonlinear forecasting tool, which is applicable in many different contexts....... The influence of the choice of kernel and the setting of tuning parameters on forecast accuracy is investigated. Several popular kernels are reviewed, including polynomial kernels, the Gaussian kernel, and the Sinc kernel. The latter two kernels are interpreted in terms of their smoothing properties......, and the tuning parameters associated to all these kernels are related to smoothness measures of the prediction function and to the signal-to-noise ratio. Based on these interpretations, guidelines are provided for selecting the tuning parameters from small grids using cross-validation. A Monte Carlo study...

  15. Marketing for Oak Ridge technology transfer

    Energy Technology Data Exchange (ETDEWEB)

    Prosser, G.A.

    1989-06-15

    Martin Marietta Energy Systems, Inc., which manages major research and production facilities in Oak Ridge, Tennessee for the Department of Energy, has implemented a systematic approach to marketing for technology transfer. Unique mechanisms have been created to address the need for market research and analysis, strategy formulation, and the execution of plans designed to engender the broadest commercial use of government-funded technologies. Establishment of formal ties with the University of Tennessee Graduate School of Business has resulted in an expanded role for marketing in support of the Oak Ridge program. The creation of graduate research positions has enabled MBA students to contribute to, and learn from, a program which is at the forefront of an important national initiative.

  16. Unfaulting the Sardarapat Ridge, Southwest Armenia

    Science.gov (United States)

    Wetmore, P.; Connor, C.; Connor, L. J.; Savov, I. P.; Karakhanyan, A.

    2012-12-01

    Armenia is located near the core of contractional deformation associated with the collision between the Arabian and Eurasian tectonic plates. Several studies of this region, including portions of adjacent Georgia, Iran, and Turkey, have indicated that 1-2 mm/yr of intra-plate, north-south shortening is primarily accommodated by a network of E-W trending thrust faults, and NW-trending (dextral) and NE-trending (sinistral) strike-slip faults. One proposed fault in this network, the Sardarapat Fault (SF), was investigated as part of a regional seismic hazard assessment ahead of the installation of a replacement reactor at the Armenian Nuclear Power Plant (ANPP). The SF is primarily defined by the Sardarapat Ridge (SR), which is a WNW-trending, 40-70 m high topographic feature located just north of the Arax River and the Turkey-Armenia border. The stratigraphy comprising this ridge includes alluvium overlying several meters of lacustrine deposits above a crystal-rich basaltic lava flow that yields an Ar-Ar age of 0.9 +/- 0.02 Ma. The alluvial sediments on the ridge contain early Bronze age (3832-3470 BP) artifacts at an elevation 25 m above those of the surrounding alluvial plane. This has lead to the suggestion that the SR is bound to the south (the steepest side) by the SF, which is uplifting the ridge at a rate of 0.7 mm/yr. However, despite the prominence and trend of the ridge there are no unequivocal observations, such as scarps or exposures of fault rocks, to support the existence of the SF. The goal of the investigation of the SR area was to test various models for the formation of the ridge including faulting and combined volcanic and erosional processes. We therefore collected gravimetric, magnetic, magneto-tellurics (MT), and transient electromagnetic (TEM) data across an area of ~400 km2, and used correlations of stratigraphic data from coreholes drilled proximal to the study area to define the geometry of the contact between the basement and basin fill to

  17. Evaluation of Bit Preservation Strategies

    DEFF Research Database (Denmark)

    Zierau, Eld; Kejser, Ulla Bøgvad; Kulovits, Hannes

    2010-01-01

    This article describes a methodology which supports evaluation of bit preservation strategies for different digital materials. This includes evaluation of alternative bit preservation solution. The methodology presented uses the preservation planning tool Plato for evaluations, and a BR......-ReMS prototype to calculate measures for how well bit preservation requirements are met. Planning storage of data as part of preservation planning involves classification of data with regard to requirements on confidentiality, bit safety, available and costs. Choice of storage with such parameters is quite...... complex since e.g. more copies of data means better bit safety, but higher cost and bigger risk of breaking confidentiality. Based on a case of a bit repository offering varied bit preservation solutions, the article will present results of using the methodology to make plans and choices of alternatives...

  18. Alveolar bone loss in osteoporosis: a loaded and cellular affair?

    Science.gov (United States)

    Jonasson, Grethe; Rythén, Marianne

    2016-01-01

    Maxillary and mandibular bone mirror skeletal bone conditions. Bone remodeling happens at endosteal surfaces where the osteoclasts and osteoblasts are situated. More surfaces means more cells and remodeling. The bone turnover rate in the mandibular alveolar process is probably the fastest in the body; thus, the first signs of osteoporosis may be revealed here. Hormones, osteoporosis, and aging influence the alveolar process and the skeletal bones similarly, but differences in loading between loaded, half-loaded, and unloaded bones are important to consider. Bone mass is redistributed from one location to another where strength is needed. A sparse trabeculation in the mandibular premolar region (large intertrabecular spaces and thin trabeculae) is a reliable sign of osteopenia and a high skeletal fracture risk. Having dense trabeculation (small intertrabecular spaces and well-mineralized trabeculae) is generally advantageous to the individual because of the low fracture risk, but may imply some problems for the clinician.

  19. Alveolar bone loss in osteoporosis: a loaded and cellular affair?

    Science.gov (United States)

    Jonasson, Grethe; Rythén, Marianne

    2016-01-01

    Maxillary and mandibular bone mirror skeletal bone conditions. Bone remodeling happens at endosteal surfaces where the osteoclasts and osteoblasts are situated. More surfaces means more cells and remodeling. The bone turnover rate in the mandibular alveolar process is probably the fastest in the body; thus, the first signs of osteoporosis may be revealed here. Hormones, osteoporosis, and aging influence the alveolar process and the skeletal bones similarly, but differences in loading between loaded, half-loaded, and unloaded bones are important to consider. Bone mass is redistributed from one location to another where strength is needed. A sparse trabeculation in the mandibular premolar region (large intertrabecular spaces and thin trabeculae) is a reliable sign of osteopenia and a high skeletal fracture risk. Having dense trabeculation (small intertrabecular spaces and well-mineralized trabeculae) is generally advantageous to the individual because of the low fracture risk, but may imply some problems for the clinician. PMID:27471408

  20. Retinoid induction of alveolar regeneration: from mice to man?

    Science.gov (United States)

    Hind, M; Gilthorpe, A; Stinchcombe, S; Maden, M

    2009-05-01

    The use of retinoids to induce human lung regeneration is under investigation in a number of studies in patients with chronic obstructive pulmonary disease (COPD). Retinoic acid (RA) has complex pleiotropic functions during vertebrate patterning and development and can induce regeneration in a number of different organ systems. Studies of retinoid signalling during lung development might provide a molecular basis to explain pharmacological induction of alveolar regeneration in adult models of lung disease. In this review the role of endogenous RA signalling during alveologenesis is explored and data suggesting that a number of exogenous retinoids can induce regeneration in the adult lung are discussed. Current controversies in this area are highlighted and a hypothesis of lung regeneration is put forward. Understanding the cellular and molecular mechanisms of induction of regeneration will be central for effective translation into patients with lung disease and may reveal novel insights into the pathogenesis of alveolar disease and senescence.

  1. The alveolar process following single-tooth extraction: a study of maxillary incisor and premolar sites in man.

    Science.gov (United States)

    Misawa, Mônica; Lindhe, Jan; Araújo, Mauricio G

    2016-07-01

    The present investigation was performed to determine some dimensional alterations that occur in the alveolar process of the incisor and premolar sites of the maxilla following tooth removal. Computer-assisted cone-beam computed tomography (CBCT) scans were obtained from the maxilla using an iCAT unit, and involved edentulous and contralateral tooth sites. For each site included in the study, parasagittal and axial reconstructions, 1 mm apart, were made and measurements of different variables (cross-sectional area, height, and width) performed. The study involved 69 subjects and disclosed that the cross-sectional area and the height and width of the alveolar process of the lateral incisor site were the smallest and those of the second premolar the largest. All parameters had been significantly reduced after the completion of the ≥1 year of healing. Thus, the overall (i) cross-sectional area was reduced from 99.1 to 65.0 mm(2) , (ii) the height from 11.5 to 9.5 mm, and (iii) the width from 8.5 to 3.2 mm (marginal 1/3(rd) ), 8.9 to 4.8 mm (middle portion), and 9.0 to 5.7 mm (apical portion). The removal of single tooth caused marked hard tissue diminution. The loss of hard tissue was most pronounced in the buccal and marginal portions of the edentulous ridge that in most sites had acquired a triangular shape. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Constitutive Parameter Measurement Using Double Ridge Waveguide

    Science.gov (United States)

    2013-03-01

    PARAMETER MEASUREMENT USING DOUBLE RIDGE WAVEGUIDE Nathan J. Lehman, B.S.E.E. Captain, USAF Approved: Michael Havrilla , PhD (Chairman) Maj Milo Hyde, PhD...would like express my gratitude to Dr. Michael Havrilla , my research advisor. Your ability to illustrate the entire picture of the subject was...electromagnetics U U U UU 83 Dr. Michael J. Havrilla (ENG) (937) 255-3636 x4582 michael.havrilla@afit.edu

  3. Fingerprint image mosaicking by recursive ridge mapping.

    Science.gov (United States)

    Choi, Kyoungtaek; Choi, Heeseung; Lee, Sangyoun; Kim, Jaihie

    2007-10-01

    To obtain a large fingerprint image from several small partial images, mosaicking of fingerprint images has been recently researched. However, existing approaches cannot provide accurate transformations for mosaics when it comes to aligning images because of the plastic distortion that may occur due to the nonuniform contact between a finger and a sensor or the deficiency of the correspondences in the images. In this paper, we propose a new scheme for mosaicking fingerprint images, which iteratively matches ridges to overcome the deficiency of the correspondences and compensates for the amount of plastic distortion between two partial images by using a thin-plate spline model. The proposed method also effectively eliminates erroneous correspondences and decides how well the transformation is estimated by calculating the registration error with a normalized distance map. The proposed method consists of three phases: feature extraction, transform estimation, and mosaicking. Transform is initially estimated with matched minutia and the ridges attached to them. Unpaired ridges in the overlapping area between two images are iteratively matched by minimizing the registration error, which consists of the ridge matching error and the inverse consistency error. During the estimation, erroneous correspondences are eliminated by considering the geometric relationship between the correspondences and checking if the registration error is minimized or not. In our experiments, the proposed method was compared with three existing methods in terms of registration accuracy, image quality, minutia extraction rate, processing time, reject to fuse rate, and verification performance. The average registration error of the proposed method was less than three pixels, and the maximum error was not more than seven pixels. In a verification test, the equal error rate was reduced from 10% to 2.7% when five images were combined by our proposed method. The proposed method was superior to other

  4. ORNL (Oak Ridge National Laboratory) 89

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, T.D.; Appleton, B.R.; Jefferson, J.W.; Merriman, J.R.; Mynatt, F.R.; Richmond, C.R.; Rosenthal, M.W.

    1989-01-01

    This is the inaugural issues of an annual publication about the Oak Ridge National Laboratory. Here you will find a brief overview of ORNL, a sampling of our recent research achievements, and a glimpse of the directions we want to take over the next 15 years. A major purpose of ornl 89 is to provide the staff with a sketch of the character and dynamics of the Laboratory.

  5. Lateral ridge augmentation with Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone graft: a systematic review.

    Science.gov (United States)

    Aludden, H C; Mordenfeld, A; Hallman, M; Dahlin, C; Jensen, T

    2017-08-01

    The objective of this systematic review was to test the hypothesis of no difference in implant treatment outcomes when using Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone grafts for lateral ridge augmentation. A search of the MEDLINE, Cochrane Library, and Embase databases in combination with a hand-search of relevant journals was conducted. Human studies published in English from 1 January 1990 to 1 May 2016 were included. The search provided 337 titles and six studies fulfilled the inclusion criteria. Considerable variation prevented a meta-analysis from being performed. The two treatment modalities have never been compared within the same study. Non-comparative studies demonstrated a 3-year implant survival of 96% with 50% Bio-Oss mixed with 50% autogenous bone graft. Moreover, Bio-Oss alone or Bio-Oss mixed with autogenous bone graft seems to increase the amount of newly formed bone as well as the width of the alveolar process. Within the limitations of this systematic review, lateral ridge augmentation with Bio-Oss alone or in combination with autogenous bone graft seems to induce newly formed bone and increase the width of the alveolar process, with high short-term implant survival. However, long-term studies comparing the two treatment modalities are needed before final conclusions can be drawn. Copyright © 2017 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  6. Evaluation of Bit Preservation Strategies

    DEFF Research Database (Denmark)

    Zierau, Eld; Kejser, Ulla Bøgvad; Kulovits, Hannes

    2010-01-01

    This article describes a methodology which supports evaluation of bit preservation strategies for different digital materials. This includes evaluation of alternative bit preservation solution. The methodology presented uses the preservation planning tool Plato for evaluations, and a BR...... for different digital material with different requirements for bit integrity and confidentiality. This case shows that the methodology, including the tools used, is useful for this purpose....

  7. Injury of the Inferior Alveolar Nerve during Implant Placement: a Literature Review

    Directory of Open Access Journals (Sweden)

    Gintaras Juodzbalys

    2011-01-01

    Full Text Available Objectives: The purpose of present article was to review aetiological factors, mechanism, clinical symptoms, and diagnostic methods as well as to create treatment guidelines for the management of inferior alveolar nerve injury during dental implant placement.Material and Methods: Literature was selected through a search of PubMed, Embase and Cochrane electronic databases. The keywords used for search were inferior alveolar nerve injury, inferior alveolar nerve injuries, inferior alveolar nerve injury implant, inferior alveolar nerve damage, inferior alveolar nerve paresthesia and inferior alveolar nerve repair. The search was restricted to English language articles, published from 1972 to November 2010. Additionally, a manual search in the major anatomy, dental implant, periodontal and oral surgery journals and books were performed. The publications there selected by including clinical, human anatomy and physiology studies.Results: In total 136 literature sources were obtained and reviewed. Aetiological factors of inferior alveolar nerve injury, risk factors, mechanism, clinical sensory nerve examination methods, clinical symptoms and treatment were discussed. Guidelines were created to illustrate the methods used to prevent and manage inferior alveolar nerve injury before or after dental implant placement.Conclusions: The damage of inferior alveolar nerve during the dental implant placement can be a serious complication. Clinician should recognise and exclude aetiological factors leading to nerve injury. Proper presurgery planning, timely diagnosis and treatment are the key to avoid nerve sensory disturbances management.

  8. An automatic early stage alveolar-bone-resorption evaluation method on digital dental panoramic radiographs

    Science.gov (United States)

    Zhang, Min; Katsumata, Akitoshi; Muramatsu, Chisako; Hara, Takeshi; Suzuki, Hiroki; Fujita, Hiroshi

    2014-03-01

    Periodontal disease is a kind of typical dental diseases, which affects many adults. The presence of alveolar bone resorption, which can be observed from dental panoramic radiographs, is one of the most important signs of the progression of periodontal disease. Automatically evaluating alveolar-bone resorption is of important clinic meaning in dental radiology. The purpose of this study was to propose a novel system for automated alveolar-bone-resorption evaluation from digital dental panoramic radiographs for the first time. The proposed system enables visualization and quantitative evaluation of alveolar bone resorption degree surrounding the teeth. It has the following procedures: (1) pre-processing for a test image; (2) detection of tooth root apices with Gabor filter and curve fitting for the root apex line; (3) detection of features related with alveolar bone by using image phase congruency map and template matching and curving fitting for the alveolar line; (4) detection of occlusion line with selected Gabor filter; (5) finally, evaluation of the quantitative alveolar-bone-resorption degree in the area surrounding teeth by simply computing the average ratio of the height of the alveolar bone and the height of the teeth. The proposed scheme was applied to 30 patient cases of digital panoramic radiographs, with alveolar bone resorption of different stages. Our initial trial on these test cases indicates that the quantitative evaluation results are correlated with the alveolar-boneresorption degree, although the performance still needs further improvement. Therefore it has potential clinical practicability.

  9. Alveolar type II epithelial cell dysfunction in rat experimental hepatopulmonary syndrome (HPS.

    Directory of Open Access Journals (Sweden)

    Wenli Yang

    Full Text Available The hepatopulmonary syndrome (HPS develops when pulmonary vasodilatation leads to abnormal gas exchange. However, in human HPS, restrictive ventilatory defects are also observed supporting that the alveolar epithelial compartment may also be affected. Alveolar type II epithelial cells (AT2 play a critical role in maintaining the alveolar compartment by producing four surfactant proteins (SPs, SP-A, SP-B, SP-C and SP-D which also facilitate alveolar repair following injury. However, no studies have evaluated the alveolar epithelial compartment in experimental HPS. In this study, we evaluated the alveolar epithelial compartment and particularly AT2 cells in experimental HPS induced by common bile duct ligation (CBDL. We found a significant reduction in pulmonary SP production associated with increased apoptosis in AT2 cells after CBDL relative to controls. Lung morphology showed decreased mean alveolar chord length and lung volumes in CBDL animals that were not seen in control models supporting a selective reduction of alveolar airspace. Furthermore, we found that administration of TNF-α, the bile acid, chenodeoxycholic acid, and FXR nuclear receptor activation (GW4064 induced apoptosis and impaired SP-B and SP-C production in alveolar epithelial cells in vitro. These results imply that AT2 cell dysfunction occurs in experimental HPS and is associated with alterations in the alveolar epithelial compartment. Our findings support a novel contributing mechanism in experimental HPS that may be relevant to humans and a potential therapeutic target.

  10. Oxidative Stress, Cell Death, and Other Damage to Alveolar Epithelial Cells Induced by Cigarette Smoke

    Directory of Open Access Journals (Sweden)

    Nagai A

    2003-09-01

    Full Text Available Abstract Cigarette smoking is a major risk factor in the development of various lung diseases, including pulmonary emphysema, pulmonary fibrosis, and lung cancer. The mechanisms of these diseases include alterations in alveolar epithelial cells, which are essential in the maintenance of normal alveolar architecture and function. Following cigarette smoking, alterations in alveolar epithelial cells induce an increase in epithelial permeability, a decrease in surfactant production, the inappropriate production of inflammatory cytokines and growth factors, and an increased risk of lung cancer. However, the most deleterious effect of cigarette smoke on alveolar epithelial cells is cell death, i.e., either apoptosis or necrosis depending on the magnitude of cigarette smoke exposure. Cell death induced by cigarette smoke exposure can largely be accounted for by an enhancement in oxidative stress. In fact, cigarette smoke contains and generates many reactive oxygen species that damage alveolar epithelial cells. Whether apoptosis and/or necrosis in alveolar epithelial cells is enhanced in healthy cigarette smokers is presently unclear. However, recent evidence indicates that the apoptosis of alveolar epithelial cells and alveolar endothelial cells is involved in the pathogenesis of pulmonary emphysema, an important cigarette smoke-induced lung disease characterized by the loss of alveolar structures. This review will discuss oxidative stress, cell death, and other damage to alveolar epithelial cells induced by cigarette smoke.

  11. Bruxism elicited by inferior alveolar nerve injury: a case report.

    Science.gov (United States)

    Melis, Marcello; Coiana, Carlo; Secci, Simona

    2012-02-01

    The aim of this case report is to describe the history of a patient who received an injury to the right inferior alveolar nerve after placement of a dental implant, with bruxism noted afterward. The symptoms were managed by the use of an occlusal appliance worn at night and occasionally during the day, associated with increased awareness of parafunction during the day to reduce muscle pain and fatigue. Paresthesia of the teeth, gingiva, and lower lip persisted but were reduced during appliance use.

  12. Primary Pulmonary Plasmacytoma with Diffuse Alveolar Consolidation: A Case Report

    Directory of Open Access Journals (Sweden)

    Zohreh Mohammad Taheri

    2010-01-01

    Full Text Available Solitary extramedullary plasmacytomas are plasma cell tumors that tend to develop in mucosa-associated lymphoid tissues including the sinonasal or nasopharyngeal regions. Primary plasmacytoma of the lung is exceedingly rare and often presents as a solitary mass or nodule in mid-lung or hilar areas and diagnosed after resection. Herein, we report a case of primary pulmonary plasmacytoma that presented with diffuse alveolar consolidation and diagnosed by transbronchial lung biopsy.

  13. Alveolar bone loss: mechanisms, potential therapeutic targets, and interventions.

    Science.gov (United States)

    Intini, G; Katsuragi, Y; Kirkwood, K L; Yang, S

    2014-05-01

    This article reviews recent research into mechanisms underlying bone resorption and highlights avenues of investigation that may generate new therapies to combat alveolar bone loss in periodontitis. Several proteins, signaling pathways, stem cells, and dietary supplements are discussed as they relate to periodontal bone loss and regeneration. RGS12 is a crucial protein that mediates osteoclastogenesis and bone destruction, and a potential therapeutic target. RGS12 likely regulates osteoclast differentiation through regulating calcium influx to control the calcium oscillation-NFATc1 pathway. A working model for RGS10 and RGS12 in the regulation of Ca(2+) oscillations during osteoclast differentiation is proposed. Initiation of inflammation depends on host cell-microbe interactions, including the p38 mitogen-activated protein kinase (MAPK) signaling pathway. Oral p38 inhibitors reduced lipopolysaccharide (LPS)-induced bone destruction in a rat periodontitis model but showed unsatisfactory safety profiles. The p38 substrate MK2 is a more specific therapeutic target with potentially superior tolerability. Furthermore, MKP-1 shows anti-inflammatory activity, reducing inflammatory cytokine biosynthesis and bone resorption. Multipotent skeletal stem cell (SSC) populations exist within the bone marrow and periosteum of long bones. These bone-marrow-derived SSCs and periosteum-derived SSCs have shown therapeutic potential in several applications, including bone and periodontal regeneration. The existence of craniofacial bone-specific SSCs is suggested based on existing studies. The effects of calcium, vitamin D, and soy isoflavone supplementation on alveolar and skeletal bone loss in post-menopausal women were investigated. Supplementation resulted in stabilization of forearm bone mass density and a reduced rate of alveolar bone loss over 1 yr, compared with placebo. Periodontal attachment levels were also well-maintained and alveolar bone loss suppressed during 24 wk of

  14. Thermal behavior of premises equipped with different alveolar structures

    OpenAIRE

    Lajimi Nour; Boukadida Noureddine

    2015-01-01

    This paper presents a numerical study of local thermal behavior. Vertical walls are equipped with alveolar structure and/or simple glazing in East, South and West frontages. Local temperature is assumed to be variable with time or imposed at set point temperature. Results principally show that the simple glazing number has a sensitive effect on convection heat transfer and interior air temperature. They also show that the diode effect is more sensitive in w...

  15. Coronectomy - A viable alternative to prevent inferior alveolar nerve injury

    Directory of Open Access Journals (Sweden)

    Alok Sagtani

    2015-12-01

    Full Text Available Background and Objectives: Coronectomy is a relatively new method to prevent the risk of Inferior Alveolar Nerve (IAN injury during removal of lower third molars with limited scientific literature among Nepalese patients. Thus, a study was designed to evaluate coronectomy regarding its use, outcomes and complications.Materials and Methods: A descriptive study was conducted from December 2012 to December 2013 among patients attending Department of Oral and Maxillofacial Surgery, College of Dental Sciences, BP Koirala Institute of Health Sciences, Dharan, Nepal for removal of mandibular third molars. After reviewing the radiograph for proximity of third molar to the IAN, coronectomy was advised. A written informed consent was obtained from the patients and coronectomy was performed. Patients were recalled after one week. The outcome measures in the follow-up visit were primary healing, pain, infection, dry socket, root exposure and IAN injury. The prevalence of IAN proximity of lower third molars and incidence of complications were calculated.Results: A total 300 mandibular third molars were extracted in 278 patients during the study period. Out of 300 impacted mandibular third molar, 41 (13.7% showed close proximity to inferior alveolar nerve . The incidence of complications and failed procedure was 7.4% among the patients who underwent coronectomy. During the follow up visit, persistent pain and root exposure was reported while other complications like inferior alveolar nerve injury, dry socket and infection was not experienced by the study patients.Conclusion: With a success rate of 92.6% among the 41 patients, coronectomy is a viable alternative to conventional total extraction for mandibular third molars who have a higher risk for damage to the inferior alveolar nerve.JCMS Nepal. 2015;11(3:1-5.

  16. Jurassic zircons from the Southwest Indian Ridge

    Science.gov (United States)

    Cheng, Hao; Zhou, Huaiyang; Yang, Qunhui; Zhang, Lingmin; Ji, Fuwu; Dick, Henry

    2016-05-01

    The existence of ancient rocks in present mid-ocean ridges have long been observed but received less attention. Here we report the discovery of zircons with both reasonably young ages of about 5 Ma and abnormally old ages of approximate 180 Ma from two evolved gabbroic rocks that were dredged from the Southwest Indian Ridge (SWIR) in the Gallieni fracture zone. U-Pb and Lu-Hf isotope analyses of zircons were made using ion probe and conventional laser abrasion directly in petrographic thin sections. Young zircons and their host oxide gabbro have positive Hf isotope compositions (ɛHf = +15.7-+12.4), suggesting a highly depleted mantle beneath the SWIR. The spread ɛHf values (from-2.3 to-4.5) of abnormally old zircons, together with the unradiogenic Nd-Hf isotope of the host quartz diorite, appears to suggest an ancient juvenile magmatism along the rifting margin of the southern Gondwana prior to the opening of the Indian Ocean. A convincing explanation for the origin of the unusually old zircons is yet to surface, however, an update of the theory of plate tectonics would be expected with continuing discovery of ancient rocks in the mid-oceanic ridges and abyssal ocean basins.

  17. Jurassic zircons from the Southwest Indian Ridge.

    Science.gov (United States)

    Cheng, Hao; Zhou, Huaiyang; Yang, Qunhui; Zhang, Lingmin; Ji, Fuwu; Dick, Henry

    2016-05-17

    The existence of ancient rocks in present mid-ocean ridges have long been observed but received less attention. Here we report the discovery of zircons with both reasonably young ages of about 5 Ma and abnormally old ages of approximate 180 Ma from two evolved gabbroic rocks that were dredged from the Southwest Indian Ridge (SWIR) in the Gallieni fracture zone. U-Pb and Lu-Hf isotope analyses of zircons were made using ion probe and conventional laser abrasion directly in petrographic thin sections. Young zircons and their host oxide gabbro have positive Hf isotope compositions (εHf = +15.7-+12.4), suggesting a highly depleted mantle beneath the SWIR. The spread εHf values (from-2.3 to-4.5) of abnormally old zircons, together with the unradiogenic Nd-Hf isotope of the host quartz diorite, appears to suggest an ancient juvenile magmatism along the rifting margin of the southern Gondwana prior to the opening of the Indian Ocean. A convincing explanation for the origin of the unusually old zircons is yet to surface, however, an update of the theory of plate tectonics would be expected with continuing discovery of ancient rocks in the mid-oceanic ridges and abyssal ocean basins.

  18. Chloride transport-driven alveolar fluid secretion is a major contributor to cardiogenic lung edema.

    Science.gov (United States)

    Solymosi, Esther A; Kaestle-Gembardt, Stefanie M; Vadász, István; Wang, Liming; Neye, Nils; Chupin, Cécile Julie Adrienne; Rozowsky, Simon; Ruehl, Ramona; Tabuchi, Arata; Schulz, Holger; Kapus, Andras; Morty, Rory E; Kuebler, Wolfgang M

    2013-06-18

    Alveolar fluid clearance driven by active epithelial Na(+) and secondary Cl(-) absorption counteracts edema formation in the intact lung. Recently, we showed that impairment of alveolar fluid clearance because of inhibition of epithelial Na(+) channels (ENaCs) promotes cardiogenic lung edema. Concomitantly, we observed a reversal of alveolar fluid clearance, suggesting that reversed transepithelial ion transport may promote lung edema by driving active alveolar fluid secretion. We, therefore, hypothesized that alveolar ion and fluid secretion may constitute a pathomechanism in lung edema and aimed to identify underlying molecular pathways. In isolated perfused lungs, alveolar fluid clearance and secretion were determined by a double-indicator dilution technique. Transepithelial Cl(-) secretion and alveolar Cl(-) influx were quantified by radionuclide tracing and alveolar Cl(-) imaging, respectively. Elevated hydrostatic pressure induced ouabain-sensitive alveolar fluid secretion that coincided with transepithelial Cl(-) secretion and alveolar Cl(-) influx. Inhibition of either cystic fibrosis transmembrane conductance regulator (CFTR) or Na(+)-K(+)-Cl(-) cotransporters (NKCC) blocked alveolar fluid secretion, and lungs of CFTR(-/-) mice were protected from hydrostatic edema. Inhibition of ENaC by amiloride reproduced alveolar fluid and Cl(-) secretion that were again CFTR-, NKCC-, and Na(+)-K(+)-ATPase-dependent. Our findings show a reversal of transepithelial Cl(-) and fluid flux from absorptive to secretory mode at hydrostatic stress. Alveolar Cl(-) and fluid secretion are triggered by ENaC inhibition and mediated by NKCC and CFTR. Our results characterize an innovative mechanism of cardiogenic edema formation and identify NKCC1 as a unique therapeutic target in cardiogenic lung edema.

  19. Chronic alcohol ingestion changes the landscape of the alveolar epithelium.

    Science.gov (United States)

    Downs, Charles A; Trac, David; Brewer, Elizabeth M; Brown, Lou Ann; Helms, My N

    2013-01-01

    Similar to effects of alcohol on the heart, liver, and brain, the effects of ethanol (EtOH) on lung injury are preventable. Unlike other vital organ systems, however, the lethal effects of alcohol on the lung are underappreciated, perhaps because there are no signs of overt pulmonary disorder until a secondary insult, such as a bacterial infection or injury, occurs in the lung. This paper provides overview of the complex changes in the alveolar environment known to occur following both chronic and acute alcohol exposures. Contemporary animal and cell culture models for alcohol-induced lung dysfunction are discussed, with emphasis on the effect of alcohol on transepithelial transport processes, namely, epithelial sodium channel activity (ENaC). The cascading effect of tissue and phagocytic Nadph oxidase (Nox) may be triggered by ethanol exposure, and as such, alcohol ingestion and exposure lead to a prooxidative environment; thus impacting alveolar macrophage (AM) function and oxidative stress. A better understanding of how alcohol changes the landscape of the alveolar epithelium can lead to improvements in treating acute respiratory distress syndrome (ARDS) for which hospitalized alcoholics are at an increased risk.

  20. Pregnancy in a patient with severe pulmonary alveolar microlithiasis.

    Science.gov (United States)

    Souza Filho, José Osmar Bezerra de; Silveira, Cristiane Maria Cavalcante; Cunha, Aline Barreto da; Pinheiro, Valéria Goes Ferreira; Feitosa, Francisco Edson de Lucena; Holanda, Marcelo Alcântara

    2008-10-01

    Pulmonary alveolar microlithiasis (PAM) is a rare disease that affects both lungs. It is characterized by the presence of small calculi (calcium phosphate) within the alveolar spaces. We report the case of a 26-year-old female whose diagnosis was based on characteristic findings on chest X-rays and high-resolution computed tomography scans. The patient, 28 weeks pregnant, was rehospitalized 10 months after the diagnosis, presenting hypoxemic acute respiratory failure and severe restrictive ventilatory defect on spirometry. After 32 completed weeks of gestation (228 days), she was submitted to cesarean section, and the outcome was successful for mother and newborn. PAM has a variable clinical course. It is suggestive of an autosomal recessive inheritance pattern and has been associated with positive family history. The etiology of PAM is unclear, and many authors speculate that there is a local enzymatic defect responsible for the intra-alveolar accumulation of calcium. Reports of patients with PAM who become pregnant are exceptional, and this is the first case described in Brazil. The course of this disease is usually slow and progressive, and patients typically die of cardiorespiratory failure. The present case illustrates the need to offer female patients, especially those with advanced disease, genetic counseling and orientation regarding the risks of pregnancy. Currently, the only effective therapy is lung transplantation.

  1. Fine needle aspiration cytology of metastatic alveolar rhabdomyosarcoma

    Directory of Open Access Journals (Sweden)

    Abhishek Sharma

    2011-01-01

    Full Text Available Rhabdomyosarcoma (RMS is an aggressive malignant soft tissue tumor that arises from primitive striated muscle cells called rhabdomyoblasts. RMS is a rare tumor in adults, and involvement of the sinonasal area is extremely rare, comprising only 1.5% of all reported head and neck RMSs. Alveolar RMS, mainly seen in adults, has the worst prognosis. Incidence of lymph node metastases is more common in this type compared with the other forms. Fine needle aspiration cytology (FNAC has been used extensively in the diagnosis of metastatic malignancies. However, metastatic soft tissue sarcomas are often overlooked, primarily due to the low frequency with which they occur. Here, we report a rare case of metastatic alveolar RMS in the cervical lymph nodes of an 18-year-old girl that was detected by FNAC. After 6 months, the patient came with a huge mass involving the nasal vestibule and the upper lip. Histology of both the main mass and the lymph nodes revealed alveolar RMS.

  2. Referral practice of military corpsmen regarding dento-alveolar trauma.

    Science.gov (United States)

    Zadik, Yehuda; Levin, Liran

    2008-06-01

    The aim of this study was to evaluate the Israeli military corpsmens' practice of referral to professional treatment regarding traumatic dental injuries. The study consisted of 250 corpsmen during their military service. Questionnaire and slide show were used to present clinical photos with short history descriptions of dento-alveolar traumatic injuries. Participants were asked to indicate the preferred referral destination for each case to state the urgency of referral to the destination and to note their regional emergency department with an oral and maxillofacial surgery consultant and the nearest 24-h emergency dental clinic. Corpsmen immediately evacuated the wounded with full-thickness lip laceration (59%), tooth avulsion (79%), alveolar fracture (88%) and mandibular fracture (100%). Most corpsmen referred crown fracture to a dental clinic and alveolar- or mandibular-bone fracture to the emergency department. Tooth avulsion cases were equally distributed between the emergency department and dental clinic and full-thickness lip laceration between the emergency department and general medical office. Familiarity with the nearest 24-h emergency dental clinic was found in 38% and with the regional emergency department with an oral and maxillofacial surgery consultant in 57%. The knowledge of this group of military corpsmen regarding referral practices was encouraging. However, further continuing education with regards to the regionally available emergency services is needed. Special emphasis should be given to provide primary caregivers with the relevant education to improve their knowledge and ability of dealing dental trauma.

  3. Massive Alveolar Hemorrhage During Wegener Granulomatosis: a Case Report

    Directory of Open Access Journals (Sweden)

    Gökhan Perincek

    2011-11-01

    Full Text Available This is a presentation of Wegener Granulomatosis (WG disease. Even though the lungs are rarely affected. massive alveolar hemorrhage is seen which leads to mortality. The patient was a 28 year old man. His illness was diagnosed as WG and glomerulonephritis a year previously and he was treated by administration of methylprednisolone orally. He had been treated irregularly. He applied to the emergency service with hemoptysis and asthma complaints two days earlier. After the results of his examination Hb: 3.6 gr/dl, Htc:10.3%, Üre:131 mg /dl, kreatini: 7.7 mg/dl, pH: 7.41, pO2: 55 mmHg, pCO2:33 mmHg, and being diagnosed as alveolar consolidation on lung X-ray, he was taken to the intensive care unit with a diagnosis of a massive alveolar hemorrhagei. He was intubated and attached to mechanical ventilation. He was treated with parenteral 1 mg/kg/day methylprednisolone and, siklofosfamid 2 mg/kg/day. He was extubated on the 21st day. He was taken to the chest service department on 24th day. He is still being treated.

  4. Thermographic assessment of reversible inferior alveolar nerve deficit.

    Science.gov (United States)

    Shetty, V; Gratt, B M; Flack, V

    1994-01-01

    The purpose of this study was to investigate thermography's potential as a diagnostic alternative for evaluating neurosensory deficits of the inferior alveolar nerve. Electronic thermography was used to evaluate the alterations in facial thermal patterns attendant to a conduction defect of the inferior alveolar nerve induced in 12 subjects using 2% lidocaine. The rates of onset and duration of sensory block, as visualized by thermography, were related to the results of conventional neurosensory testing. Comparison of the rate of response change within each measurement system revealed that changes in facial skin temperature manifest the induced deficit earlier than discriminative tests. Also, the prolonged elevation of thermal asymmetry suggested that electronic thermography has the ability to detect subtle changes in nerve function that are not discernible by physical neurosensory tests relying on patient response. Although cutaneous temperature increases were highest in the field of observation near the sensory distribution of the mental nerve, an inexplicable warming of the contralateral side of the face and neck was also observed. These attendant findings emphasize the need for further studies on the pathophysiologic mechanisms of facial thermal changes to better understand thermography's diagnostic accuracy and clinical utility for monitoring inferior alveolar nerve dysfunction.

  5. Alveolar epithelial type II cell: defender of the alveolus revisited

    Directory of Open Access Journals (Sweden)

    Fehrenbach Heinz

    2001-01-01

    Full Text Available Abstract In 1977, Mason and Williams developed the concept of the alveolar epithelial type II (AE2 cell as a defender of the alveolus. It is well known that AE2 cells synthesise, secrete, and recycle all components of the surfactant that regulates alveolar surface tension in mammalian lungs. AE2 cells influence extracellular surfactant transformation by regulating, for example, pH and [Ca2+] of the hypophase. AE2 cells play various roles in alveolar fluid balance, coagulation/fibrinolysis, and host defence. AE2 cells proliferate, differentiate into AE1 cells, and remove apoptotic AE2 cells by phagocytosis, thus contributing to epithelial repair. AE2 cells may act as immunoregulatory cells. AE2 cells interact with resident and mobile cells, either directly by membrane contact or indirectly via cytokines/growth factors and their receptors, thus representing an integrative unit within the alveolus. Although most data support the concept, the controversy about the character of hyperplastic AE2 cells, reported to synthesise profibrotic factors, proscribes drawing a definite conclusion today.

  6. Modelling Organizational Preservation Goals to Guide Digital Preservation

    Directory of Open Access Journals (Sweden)

    Angela Dappert

    2009-10-01

    Full Text Available This paper is an extended and updated version of the work reported at iPres 2008. Digital preservation activities can only succeed if they go beyond the technical properties of digital objects. They must consider the strategy, policy, goals, and constraints of the institution that undertakes them and take into account the cultural and institutional framework in which data, documents and records are preserved. Furthermore, because organizations differ in many ways, a one-size-fits-all approach cannot be appropriate. Fortunately, organizations involved in digital preservation have created documents describing their policies, strategies, work-flows, plans, and goals to provide guidance. They also have skilled staff who are aware of sometimes unwritten considerations. Within Planets (Farquhar & Hockx-Yu, 2007, a four-year project co-funded by the European Union to address core digital preservation challenges, we have analyzed preservation guiding documents and interviewed staff from libraries, archives, and data centres that are actively engaged in digital preservation. This paper introduces a conceptual model for expressing the core concepts and requirements that appear in preservation guiding documents. It defines a specific vocabulary that institutions can reuse for expressing their own policies and strategies. In addition to providing a conceptual framework, the model and vocabulary support automated preservation planning tools through an XML representation.

  7. Two kinds of bone in the extraction socket preservation preliminary observation on the clinical ef ect of intraoperative%两种骨粉在拔牙窝保存术中临床效果的初步观察

    Institute of Scientific and Technical Information of China (English)

    张鑫

    2015-01-01

    extraction without any intervention.1,3,6 months,to observe the healing of extraction sockets.Before extraction and extraction after 6 months of intraoralmodulo plaster casting and X -ray radiograph,the alveolar ridge height and width were measured,by statistical analysis,P <0.05,the dif erence was statistical y significant.Results:in 60 cases,bone and bone meal group group of imported domestic sockets healed wel ,alveolar bone plump,gingival,shape,quality and coordination of adjacent teeth.The alveolarbone have been ef ectively protected,the alveolar ridge width can meet the clinical needs of planting.While the control group of alveolar bone resorption,atrophy,reduced height,widthwas significantly reduced.By comparison,the im-port of bone (Bio -Oss)group,the indexes ofthe smal est,domestic bone (hydroxyapatite)group,blank control group,the biggest change.Conclusion:Bio -Oss or hydroxyapatite artificial bone in implanted into the socket immediately after extraction,can ef ectively protect the alveolar bone,maintain alveolar bone morphology,the successful completion of planting operation,good aesthetic ef ect of soft tissue.Domesticmeal is more economical and practical,suitable for promotion in underdeveloped areas.

  8. Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type II cells

    Directory of Open Access Journals (Sweden)

    Richter Joachim

    2008-01-01

    Full Text Available Abstract Background Prophylactic exogenous surfactant therapy is a promising way to attenuate the ischemia and reperfusion (I/R injury associated with lung transplantation and thereby to decrease the clinical occurrence of acute lung injury and acute respiratory distress syndrome. However, there is little information on the mode by which exogenous surfactant attenuates I/R injury of the lung. We hypothesized that exogenous surfactant may act by limiting pulmonary edema formation and by enhancing alveolar type II cell and lamellar body preservation. Therefore, we investigated the effect of exogenous surfactant therapy on the formation of pulmonary edema in different lung compartments and on the ultrastructure of the surfactant producing alveolar epithelial type II cells. Methods Rats were randomly assigned to a control, Celsior (CE or Celsior + surfactant (CE+S group (n = 5 each. In both Celsior groups, the lungs were flush-perfused with Celsior and subsequently exposed to 4 h of extracorporeal ischemia at 4°C and 50 min of reperfusion at 37°C. The CE+S group received an intratracheal bolus of a modified natural bovine surfactant at a dosage of 50 mg/kg body weight before flush perfusion. After reperfusion (Celsior groups or immediately after sacrifice (Control, the lungs were fixed by vascular perfusion and processed for light and electron microscopy. Stereology was used to quantify edematous changes as well as alterations of the alveolar epithelial type II cells. Results Surfactant treatment decreased the intraalveolar edema formation (mean (coefficient of variation: CE: 160 mm3 (0.61 vs. CE+S: 4 mm3 (0.75; p 3 (0.90 vs. CE+S: 0 mm3; p 3 (0.39 vs. CE+S: 268 mm3 (0.43; p 3(0.10 and CE+S (481 μm3(0.10 compared with controls (323 μm3(0.07; p Conclusion Intratracheal surfactant application before I/R significantly reduces the intraalveolar edema formation and development of atelectases but leads to an increased development of

  9. Resource management plan for the Oak Ridge Reservation. Volume 27, Wildlife Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Parr, P.D. [Oak Ridge National Lab., TN (United States); Evans, J.W. [Tennessee Wildlife Resources Agency, Knoxville, TN (United States)

    1992-06-01

    A plan for management of the wildlife resources on the US Department of Energy`s Oak Ridge Reservation is outlined in this document. Management includes wildlife population control (hunts, trapping, and removal), handling specific problems with wildlife, restoration of species, coordination with researchers on wildlife studies, preservation and management of habitats, and law enforcement. Wildlife resources are divided into five categories, each with a specific set of objectives and procedures for obtaining these objectives. These categories are (1) species-richness management to ensure that all resident wildlife species exist on the Reservation in viable numbers; (2) featured species management to produce selected species in desired numbers on designated land units; (3) management of game species for research, education, recreation, and public safety, (4) endangered species management designed to preserve and protect both the species and habitats critical to the survival of those species; and (5) pest management. Achievement of the objectives is a joint effort between the Tennessee Wildlife Resources Agency and the Oak Ridge National Laboratory`s Environmental Sciences Division.

  10. Influence of the Alveolar Cleft Type on Preoperative Estimation Using 3D CT Assessment for Alveolar Cleft

    Directory of Open Access Journals (Sweden)

    Hang Suk Choi

    2012-09-01

    Full Text Available BackgroundThe bone graft for the alveolar cleft has been accepted as one of the essential treatments for cleft lip patients. Precise preoperative measurement of the architecture and size of the bone defect in alveolar cleft has been considered helpful for increasing the success rate of bone grafting because those features may vary with the cleft type. Recently, some studies have reported on the usefulness of three-dimensional (3D computed tomography (CT assessment of alveolar bone defect; however, no study on the possible implication of the cleft type on the difference between the presumed and actual value has been conducted yet. We aimed to evaluate the clinical predictability of such measurement using 3D CT assessment according to the cleft type.MethodsThe study consisted of 47 pediatric patients. The subjects were divided according to the cleft type. CT was performed before the graft operation and assessed using image analysis software. The statistical significance of the difference between the preoperative estimation and intraoperative measurement was analyzed.ResultsThe difference between the preoperative and intraoperative values were -0.1±0.3 cm3 (P=0.084. There was no significant intergroup difference, but the groups with a cleft palate showed a significant difference of -0.2±0.3 cm3 (P<0.05.ConclusionsAssessment of the alveolar cleft volume using 3D CT scan data and image analysis software can help in selecting the optimal graft procedure and extracting the correct volume of cancellous bone for grafting. Considering the cleft type, it would be helpful to extract an additional volume of 0.2 cm3 in the presence of a cleft palate.

  11. Influence of the Alveolar Cleft Type on Preoperative Estimation Using 3D CT Assessment for Alveolar Cleft

    Directory of Open Access Journals (Sweden)

    Hang Suk Choi

    2012-09-01

    Full Text Available Background The bone graft for the alveolar cleft has been accepted as one of the essentialtreatments for cleft lip patients. Precise preoperative measurement of the architecture andsize of the bone defect in alveolar cleft has been considered helpful for increasing the successrate of bone grafting because those features may vary with the cleft type. Recently, somestudies have reported on the usefulness of three-dimensional (3D computed tomography(CT assessment of alveolar bone defect; however, no study on the possible implication of thecleft type on the difference between the presumed and actual value has been conducted yet.We aimed to evaluate the clinical predictability of such measurement using 3D CT assessmentaccording to the cleft type.Methods The study consisted of 47 pediatric patients. The subjects were divided according tothe cleft type. CT was performed before the graft operation and assessed using image analysissoftware. The statistical significance of the difference between the preoperative estimationand intraoperative measurement was analyzed.Results The difference between the preoperative and intraoperative values were -0.1±0.3cm3 (P=0.084. There was no significant intergroup difference, but the groups with a cleftpalate showed a significant difference of -0.2±0.3 cm3 (P<0.05.Conclusions Assessment of the alveolar cleft volume using 3D CT scan data and image analysissoftware can help in selecting the optimal graft procedure and extracting the correct volumeof cancellous bone for grafting. Considering the cleft type, it would be helpful to extract anadditional volume of 0.2 cm3 in the presence of a cleft palate.

  12. Structural, geochronological, magnetic and magmatic constraints of a ridge collision/ridge subduction-related ophiolite

    Science.gov (United States)

    Anma, Ryo

    2013-04-01

    A mid-oceanic ridge system subducts underneath South American plate at latitude 46S off Chilean coast, forming a ridge-trench-trench type triple junction. At ~ 6 Ma, a short segment of the Chile ridge system subducted in south of the present triple junction. This ridge subduction event resulted in emplacement of a young ophiolite (5. 6 to 5. 2 Ma) and rapid crustal uplift (partly emerged after 4.9 Ma), and synchronous magmatism. This ophiolite, namely the Taitao ophiolite, provides criteria for the recognition of ridge collision/ridge subduction-related ophiolites. Aiming to establish recognition criteria, we studied distribution of structures, magnetic properties, geochemical characteristics, and radiometric ages of the Taitao ophiolite and related igneous rocks. The Taitao ophiolite exhibits a classic Penrose-type stratigraphy: ultramafic rocks and gabbros (collectively referred as plutonic section hereafter) in the south, and sheeted dike complex (SDC) and volcanic sequences in the north. Composite foliations developed in the plutonic section, which were folded. SDC were exposed in two isolated blocks having orthogonal strikes of dike margins. Geochemically, gabbros have an N-MORB composition whereas basalts of the volcanic sequence have an E-MORB composition. U-Pb ages of zircons separated from gabbros, SDC and sediments interbeded with billow lavas implied that the center of magmatic activities migrated from the plutonic section to volcanic section during ~5.6 Ma and ~5.2 Ma. Zircon fission track ages of gabbros coincide with U-Pb ages within error range, implying rapid cooling. Demagnetization paths for SDC and lavas form a straight line, whereas those from the plutonic section are Z-shaped and divisble into two components: low coercivity and high coercivity. Restored orientation of gabbro structures imply that the magnetization acquired while gabbroic structures were folding. Thus, magma genesis and emplacement of the plutonic section of ophiolite took place

  13. The use of digital periapical radiographs to study the prevalence of alveolar domes

    Science.gov (United States)

    Xambre, Pedro Augusto Oliveira Santos; Valerio, Claudia Scigliano; e Alves Cardoso, Claudia Assunção; Custódio, Antônio Luís Neto

    2016-01-01

    Purpose In the present study, we coined the term 'alveolar dome' and aimed to demonstrate the prevalence of alveolar domes through digital periapical radiographs. Materials and Methods This study examined 800 digital periapical radiographs in regard to the presence of alveolar domes. The periapical radiographs were acquired by a digital system using a photostimulable phosphor (PSP) plate. The χ2 test, with a significance level of 5%, was used to compare the prevalence of alveolar domes in the maxillary posterior teeth and, considering the same teeth, to verify the difference in the prevalence of dome-shaped phenomena between the roots. Results The prevalence of alveolar domes present in the first pre-molars was statistically lower as compared to the other maxillary posterior teeth (pauxiliary information necessary to identify alveolar domes, thus improving diagnosis, planning, and treatment. PMID:27672614

  14. First Recovery of Submarine Basalts from the Chukchi Borderland and Alpha / Mendeleev Ridge, Arctic Ocean

    Science.gov (United States)

    Andronikov, A.; Mukasa, S.; Mayer, L. A.; Brumley, K.

    2008-12-01

    In addition to multibeam bathymetric mapping of the Amerasia Basin in the high Arctic Ocean, the August- September 2008 cruise of USCGC Icebreaker HEALY (HLY0805) conducted a total of seven dredging profiles along the southern sectors of the Alpha/Mendeleev Ridge and in the northernmost region of Northwind Ridge of Chukchi Borderland. Five of the seven dredges were recovered on relatively gentle slopes (30-40°) and yielded mostly mud with a small number of fragments of sedimentary rocks and ice rafted debris (IRD), which indicates either rapid sedimentation rates on the bathymetrically high features sampled or lack of recently active volcanism on these features. Two dredges taken from steep escarpments with slopes (> 55°) at >3.5 km depth recovered some of the first known submarine basaltic samples from the Arctic Ocean floor away from the Gakkel Ridge. Ragged, freshly exposed edges indicate that these samples were broken from outcrop rather than being IRD. In some cases (e.g., a rise on the ocean floor between the Alpha/Mendeleev Ridge and Northwind Ridge) the samples have well-preserved pillow-basalt structures with fresh glassy rims up to 4 cm thick. Inward from the rims, the rocks are dark-grey lavas, some with visible plagioclase laths and rare phenocrysts up to 0.5 mm in length, some with visible signs of alteration such as local occurrence of chlorite. Surfaces that were exposed to water can be covered with a thin black film of Mn oxides. Occurrence of this volcanism away from any obvious spreading centers compels us to hypothesize that forthcoming geochemical analyses are likely to identify these rocks as the first Arctic Ocean floor samples to exhibit ocean island basalt compositions. The dredge taken from the northern slope of Northwind Ridge, along slopes as steep as > 45°, recovered a variety of rock types including sedimentary and basaltic rocks. Some of the basalts have columnar jointing (the size of the columns is only up to 5-6 cm across

  15. GIS compilation of data collected from the Pulley Ridge Deep Coral Reef region

    Science.gov (United States)

    Cross, VeeAnn; Twichell, D.C.; Halley, R.B.; Ciembronowicz, K.T.; Jarrett, B.D.; Hammar-Klose, E.S.; Hine, A.C.; Locker, S.D.; Naar, D.F.

    2005-01-01

    Pulley Ridge is a chain of drowned barrier islands that extends almost 200 km in 60-90 m water depths (Fig. 1). This drowned ridge is located on the Florida Platform in the southeastern Gulf of Mexico about 250 km west of Cape Sable, Florida (Jarrett and others, 2005). These islands formed during the early Holocene marine transgression approximately 12,000 - 14,000 years before present, and were then submerged by sea level rise and preserved near the outer edge of the Florida Platform. The southern portion of Pulley Ridge is the focus of this study. This area hosts zooxanthellate scleractinian corals, green, red and brown macro algae, and a mix of deep and typically shallow-water tropical fishes. This largely photosynthetic community is unique in that it thrives with less than 5% of the light typically associated with shallow-water reefs with similar fauna.L Several factors help to account for the existence of this unique deep-water community. First, the underlying drowned barrier islands provide both elevated topography and lithified substrate for the establishment of the hardbottom community. Second, the region is commonly bathed by the Loop Current, which brings relatively clear and warm water to this area. Third, the ridge's position on the continental shelf places it within the thermocline which provides nutrients to the reef during upwelling (Halley and others, 2003). The USGS has made two proposals to resource managers for the designation of marine protected areas based on the geophysical and photographic data in this report. The proposals describe areas that may require some regulatory protection of marine life utilizing the sea floor (Fig. 1). The first proposal is that the area of greatest hermatypic coral cover (Fig. 1) is considered for future management actions and designated a Habitat Area of Particular Concern (HAPC) by the Gulf of Mexico Fishery Management Council. HAPCs are identified on the basis of habitat level considerations: - The importance

  16. User Experience and Heritage Preservation

    Science.gov (United States)

    Orfield, Steven J.; Chapman, J. Wesley; Davis, Nathan

    2011-01-01

    In considering the heritage preservation of higher education campus buildings, much of the attention gravitates toward issues of selection, cost, accuracy, and value, but the model for most preservation projects does not have a clear method of achieving the best solutions for meeting these targets. Instead, it simply relies on the design team and…

  17. User Experience and Heritage Preservation

    Science.gov (United States)

    Orfield, Steven J.; Chapman, J. Wesley; Davis, Nathan

    2011-01-01

    In considering the heritage preservation of higher education campus buildings, much of the attention gravitates toward issues of selection, cost, accuracy, and value, but the model for most preservation projects does not have a clear method of achieving the best solutions for meeting these targets. Instead, it simply relies on the design team and…

  18. Preservation Methods for Digital Library

    Science.gov (United States)

    Rajendran, L.; Venkatesan, M.; Kanthimathi, S.

    2005-01-01

    Going digital is the way to minimize handling of damaged materials, but the imaging process is demanding and must be done with oversight by preservation staff and with a high enough level of quality to ensure the reusability of the archival electronic file for as long as possible. This paper focuses on the scope and needs of digital preservation,…

  19. Contact dermatitis caused by preservatives.

    Science.gov (United States)

    Yim, Elizabeth; Baquerizo Nole, Katherine L; Tosti, Antonella

    2014-01-01

    Preservatives are biocidal chemicals added to food, cosmetics, and industrial products to prevent the growth of microorganisms. They are usually nontoxic and inexpensive and have a long shelf life. Unfortunately, they commonly cause contact dermatitis. This article reviews the most important classes of preservatives physicians are most likely to encounter in their daily practice, specifically isothiazolinones, formaldehyde and formaldehyde-releasers, iodopropynyl butylcarbamate, methyldibromoglutaronitrile, and parabens. For each preservative mentioned, the prevalence of sensitization, clinical presentation of contact dermatitis, patch testing concentrations, cross reactions, and related legislation will be discussed. Mandatory labeling of preservatives is required in some countries, but not required in others. Until policies are made, physicians and patients must be proactive in identifying potential sensitizers and removing their use. We hope that this article will serve as a guide for policy makers in creating legislation and future regulations on the use and concentration of certain preservatives in cosmetics and industrial products.

  20. Injury of the Inferior Alveolar Nerve during Implant Placement: a Literature Review

    OpenAIRE

    Gintaras Juodzbalys; Hom-Lay Wang; Gintautas Sabalys

    2011-01-01

    ABSTRACT Objectives The purpose of present article was to review aetiological factors, mechanism, clinical symptoms, and diagnostic methods as well as to create treatment guidelines for the management of inferior alveolar nerve injury during dental implant placement. Material and Methods Literature was selected through a search of PubMed, Embase and Cochrane electronic databases. The keywords used for search were inferior alveolar nerve injury, inferior alveolar nerve injuries, inferior alveo...