Full Text Available Abstract Background Altruistic anti-predatory behaviours pose an evolutionary problem because they are costly to the actor and beneficial to the recipients. Altruistic behaviours can evolve through indirect fitness benefits when directed toward kin. The altruistic nature of anti-predatory behaviours is often difficult to establish because the actor can obtain direct fitness benefits, or the behaviour could result from selfish coercion by others, especially in eusocial animals. Non-eusocial parthenogenetically reproducing aphids form colonies of clone-mates, which are ideal to test the altruistic nature of anti-predatory defence behaviours. Many aphids release cornicle secretions when attacked by natural enemies such as parasitoids. These secretions contain an alarm pheromone that alerts neighbours (clone-mates of danger, thereby providing indirect fitness benefits to the actor. However, contact with cornicle secretions also hampers an attacker and could provide direct fitness to the actor. Results We tested the hypothesis that cornicle secretions are altruistic by assessing direct and indirect fitness consequences of smearing cornicle secretions onto an attacker, and by manipulating the number of clone-mates that could benefit from the behaviour. We observed parasitoids, Aphidius rhopalosiphi, foraging singly in patches of the cereal aphid Sitobion avenae of varied patch size (2, 6, and 12 aphids. Aphids that smeared parasitoids did not benefit from a reduced probability of parasitism, or increase the parasitoids' handling time. Smeared parasitoids, however, spent proportionately more time grooming and less time foraging, which resulted in a decreased host-encounter and oviposition rate within the host patch. In addition, individual smearing rate increased with the number of clone-mates in the colony. Conclusions Cornicle secretions of aphids were altruistic against parasitoids, as they provided no direct fitness benefits to secretion
Full Text Available Previous studies find a strong relationship between job satisfaction and altruistic OCB. The aim of this study is to investigate the effects of a different kind of employee satisfaction, namely the extent to which employees are satisfied with the career opportunities that their organization offers. Based on social exchange theory, two contrasting hypotheses are formulated and tested. Hypothesis 1 argues that satisfaction with career opportunities is positively related to altruistic OCB because it strengthens the relationship between employees and organizations. Hypothesis 2 states that altruistic OCB is part of the horizontal exchange relationship between co-workers and that career opportunities are negatively related to this kind of behaviour since it disrupts the social exchanges taking place between co-workers. The hypotheses are investigated using survey data from 280 employees. Ordinary least squares (OLS regression is applied to analyze the data. The empirical analyses find support for Hypothesis 2: career satisfaction is negatively related to altruistic OCB. The practical implication of this research concerns the potential trade-off between career satisfaction and employees' levels of altruistic OCB. This indicates that strengthening vertical organizational relationships may weaken horizontal relationships. For managers this implies that they have to take this trade-off into account if they want to sustain altruistic OCB. Research on OCB focused mainly on the vertical exchange relationship within organizations. This article also includes the horizontal dimension and shows how it may be related to employee behaviour.
Metzler, D; Jordan, F; Pamminger, T; Foitzik, S
How can antiparasite defence traits evolve even if they do not directly benefit their carriers? An example of such an indirect defence is rebellion of enslaved Temnothorax longispinosus ant workers against their social parasite Temnothorax americanus, a slavemaking ant. Ant slaves have been observed to kill their oppressors' offspring, a behaviour from which the sterile slaves cannot profit directly. Parasite brood killing could, however, reduce raiding pressure on related host colonies nearby. We analyse with extensive computer simulations for the Temnothorax slavemaker system under what conditions a hypothetical rebel allele could invade a host population, and in particular, how host-parasite dynamics and population structure influence the rebel allele's success. Exploring a wide range of model parameters, we only found a small number of parameter combinations for which kin selection or multilevel selection could allow a slave rebellion allele to spread in the host population. Furthermore, we did not detect any cases in which the reduction of raiding pressure in the close vicinity of the slavemaker nest would substantially contribute to the inclusive fitness of rebels. This suggests that slave rebellion is not costly and perhaps a side-effect of some other beneficial trait. In some of our simulations, however, even a costly rebellion allele could spread in the population. This was possible when host-parasite interactions led to a metapopulation dynamic with frequent local extinctions and recolonizations of demes by the offspring of few immigrants. PMID:26873305
Full Text Available The origin of altruism remains one of the most enduring puzzles of human behaviour. Indeed, true altruism is often thought either not to exist, or to arise merely as a miscalculation of otherwise selfish behaviour. In this paper, we argue that altruism emerges directly from the way in which distinct human decision-making systems learn about rewards. Using insights provided by neurobiological accounts of human decision-making, we suggest that reinforcement learning in game-theoretic social interactions (habitization over either individuals or games and observational learning (either imitative of inference based lead to altruistic behaviour. This arises not only as a result of computational efficiency in the face of processing complexity, but as a direct consequence of optimal inference in the face of uncertainty. Critically, we argue that the fact that evolutionary pressure acts not over the object of learning ('what' is learned, but over the learning systems themselves ('how' things are learned, enables the evolution of altruism despite the direct threat posed by free-riders.
Seymour, Ben; Yoshida, Wako; Dolan, Ray
The origin of altruism remains one of the most enduring puzzles of human behaviour. Indeed, true altruism is often thought either not to exist, or to arise merely as a miscalculation of otherwise selfish behaviour. In this paper, we argue that altruism emerges directly from the way in which distinct human decision-making systems learn about rewards. Using insights provided by neurobiological accounts of human decision-making, we suggest that reinforcement learning in game-theoretic social interactions (habitisation over either individuals or games) and observational learning (either imitative of inference based) lead to altruistic behaviour. This arises not only as a result of computational efficiency in the face of processing complexity, but as a direct consequence of optimal inference in the face of uncertainty. Critically, we argue that the fact that evolutionary pressure acts not over the object of learning ('what' is learned), but over the learning systems themselves ('how' things are learned), enables the evolution of altruism despite the direct threat posed by free-riders. PMID:19826495
Lynch, Z R; Schlenke, T A; de Roode, J C
It may be intuitive to predict that host immune systems will evolve to counter a broad range of potential challenges through simultaneous investment in multiple defences. However, this would require diversion of resources from other traits, such as growth, survival and fecundity. Therefore, ecological immunology theory predicts that hosts will specialize in only a subset of possible defences. We tested this hypothesis through a comparative study of a cellular immune response and a putative behavioural defence used by eight fruit fly species against two parasitoid wasp species (one generalist and one specialist). Fly larvae can survive infection by melanotically encapsulating wasp eggs, and female flies can potentially reduce infection rates in their offspring by laying fewer eggs when wasps are present. The strengths of both defences varied significantly but were not negatively correlated across our chosen host species; thus, we found no evidence for a trade-off between behavioural and cellular immunity. Instead, cellular defences were significantly weaker against the generalist wasp, whereas behavioural defences were similar in strength against both wasps and positively correlated between wasps. We investigated the adaptive significance of wasp-induced oviposition reduction behaviour by testing whether wasp-exposed parents produce offspring with stronger cellular defences, but we found no support for this hypothesis. We further investigated the sensory basis of this behaviour by testing mutants deficient in either vision or olfaction, both of which failed to reduce their oviposition rates in the presence of wasps, suggesting that both senses are necessary for detecting and responding to wasps. PMID:26859227
The focus of many disciplines on cooperation as a strategy for effective societal functioning stimulates continuing debate on altruism generally and altruistic leadership more specifically. Theoretical articulation of the concept of altruistic leadership is limited, with most leadership scholars focusing on self-sacrificial behaviours, rather than leaders’ motivational state. This thesis draws on the social science literature to address the question of the nature of altruistic leadership and ...
Full Text Available Orientation: Positive Psychology’s focus on positive behaviour has resulted in research and organisational consultants to focus relatively more on positive behaviour, thus avoiding negative and often unconscious behaviour and its manifestations.Research purpose: The aim of the study was to explore the systems psychodynamic nature of the manifesting defensive structures operating in Positive Psychology.Motivation for the study: The study investigated the popularity of Positive Psychology amongst academics, students and organisational consultants and the tendency to avoid the complexity of the relatedness between positive and negative as part of the human condition.Research design, approach and method: Qualitative research by means of a Listening Post was used, consisting of six psychologists in their roles as lecturers and organisational consultants. Thematic analyses led to the formulation of various working hypotheses, integrated into a research hypothesis.Main findings: Four themes manifested – namely, the manifesting defence mechanisms, a reluctance to relinquish positive psychology as an object of hope, a need to guard against being too hasty in breaking down positive psychology and a need for a psychology that can engage us in a conversation about integrating the complexities of the human condition.Practical/managerial implications: The findings were linked to Deo Strümpfer’s work, indicating that Positive Psychology originated in early 20th century psychology, which is indeed not about simplification, but is imbedded in the complexity of various behavioural continua.Contribution/value-add: Academics, students and organisational consultants are encouraged to revisit Strümpfer’s work to ensure that this psychology is appreciated for its depth and quality.
To study how immunity is achieved in insect societies I investigated the antiparasite defence of mainly the invasive garden ant Lasius neglectus when exposed to the entomopathogenic fungus Metarhizium anisopliae. In the first three chapters I focused on behavioural aspects of the social immune system with special reference to hygienic actions toward brood. In Chapter I I could first demonstrate a potential protective function of the cocoon-enclosure around pupae in ants when exposed to fun...
Stökl, Johannes; Machacek, Zora; Ruther, Joachim
Many insects use chemical defence mechanisms to defend themselves against predators. However, defensive secretions are costly to produce and should thus only be used in cases of real danger. This would require that insects are able to discriminate between predators to adjust their chemical defence. Here, we show that females of the parasitoid wasp Leptopilina heterotoma adjust the intensity of their chemical defence to differently sized predators. If attacked by Myrmica ants, the females always released their defensive secretion, which consists mainly of (-)-iridomyrmecin. However, if attacked by smaller Cardiocondyla ants, most females did not release any defensive spray, irrespective of the duration of the ant's aggression. When in contact with non-aggressive Nasonia wasps, the females of L. heterotoma did not release any defensive secretion. Our data show that females of L. heterotoma are able to discriminate between two predators and suggest that a predator of a certain size or strength is necessary to trigger the chemical defence mechanism of L. heterotoma.
Full Text Available The well-being of the individuals, and the social groups, and not the welfare of the society as such, is always the ultimate end of morality. The welfare of society as a whole is a means to the welfare of the units. In the early stages of social evolution, egoism is strong and altruism weak. The moral code prohibits acts of aggression and imposes restraints on the individual in the interest of co-operation. Altruism is essential to the development of life and the increase of happiness, and self-sacrifice is no less primordial than self-preservation. The egoistic satisfactions of each individual in a society depend on such altruistic actions as being just, seeing justice done, upholding and improving the agencies for the administration of justice and improving others physically, intellectually, and morally, pure egoism and pure altruism are equally illegitimate. In the words of Auguste Comte Altruism is the opposite of Egoism. This paper discusses Gandhiji's view about Altruistic Education. The present educational system has to be such that every boy and girl is able to know, love and do good and promote a culture of acceptance, tolerance and love for social justice.
Frans Cilliers; Michelle May
Orientation: Positive Psychology’s focus on positive behaviour has resulted in research and organisational consultants to focus relatively more on positive behaviour, thus avoiding negative and often unconscious behaviour and its manifestations.Research purpose: The aim of the study was to explore the systems psychodynamic nature of the manifesting defensive structures operating in Positive Psychology.Motivation for the study: The study investigated the popularity of Positive Psychology among...
Fullard, James H; Jackson, Matt E; Jacobs, David S; Pavey, Chris R; Burwell, Chris J
The Australian noctuid moth, Speiredonia spectans shares its subterranean day roosts (caves and abandoned mines) with insectivorous bats, some of which prey upon it. The capacity of this moth to survive is assumed to arise from its ability to listen for the bats' echolocation calls and take evasive action; however, the auditory characteristics of this moth or any tropically distributed Australian moth have never been examined. We investigated the ears of S. spectans and determined that they are among the most sensitive ever described for a noctuid moth. Using playbacks of cave-recorded bats, we determined that S. spectans is able to detect most of the calls of two co-habiting bats, Rhinolophus megaphyllus and Miniopterus australis, whose echolocation calls are dominated by frequencies ranging from 60 to 79 kHz. Video-recorded observations of this roost site show that S. spectans adjusts its flight activity to avoid bats but this defence may delay the normal emergence of the moths and leave some 'pinned down' in the roosts for the entire night. At a different day roost, we observed the auditory responses of one moth to the exceptionally high echolocation frequencies (150-160 kHz) of the bat Hipposideros ater and determined that S. spectans is unable to detect most of its calls. We suggest that this auditory constraint, in addition to the greater flight manoeuvrability of H. ater, renders S. spectans vulnerable to predation by this bat to the point of excluding the moth from day roosts where the bat occurs. PMID:19043053
David Parker, R; Regier, Michael D; Widmeyer, Joseph; Honaker, John; Rüütel, Kristi
Limited research exists on sexually transmitted infection (STI) and risk behaviour among military personnel. Published research on condom use and types of contraceptives used yield mixed results, yet, the perception that military members are at higher risk for STIs remains. The objectives of this cross-sectional study were to measure factors such as condom use, contraceptive methods, and risky behaviours (i.e. drug use and sex with commercial sex workers) and investigate differences between ethnic groups, where culture could influence behaviour. Data were collected from a recruited population of 584 male, military conscripts in northeastern Europe. Using multinomial logistic regression models, statistically significant findings include an interaction between the use of contraceptive methods of Russians with casual partners and ethnicity, with higher odds of effective methods used among Estonians with regular partners (OR = 8.13) or casual partners (OR = 11.58) and Russians with regular partners (OR = 4.98). Effective contraceptive methods used less frequently with casual partners by ethnic Russians is important in providing education and risk reduction services to young, male conscripts. These findings may be used as a baseline to inform health education and STI prevention programmes tailored to military members in Eastern Europe in the absence of other published studies. PMID:25324351
Hilke A.M. Grootelaar; Tjalling A. Waterbolk; Jakoline Winkels
This paper presents the results of eight case studies of post-defence hearings in a Dutch court, in which the judge was questioned about his role conception, judicial behaviour at the hearing was observed and parties were interviewed about their perception of procedural justice after the hearing. A large part of the findings are in line with former research on procedural justice. Nevertheless, self-generated answers by the respondents revealed interesting miscellaneous findings. The main aim ...
Marsh, Abigail A.; Stoycos, Sarah A.; Brethel-Haurwitz, Kristin M.; Robinson, Paul; VanMeter, John W.; Cardinale, Elise M.
Altruistic behavior improves the welfare of another individual while reducing the altruist’s welfare. Humans’ tendency to engage in altruistic behaviors is unevenly distributed across the population, and individual variation in altruistic tendencies may be genetically mediated. Although neural endophenotypes of heightened or extreme antisocial behavior tendencies have been identified in, for example, studies of psychopaths, little is known about the neural mechanisms that support heightened or extreme prosocial or altruistic tendencies. In this study, we used structural and functional magnetic resonance imaging to assess a population of extraordinary altruists: altruistic kidney donors who volunteered to donate a kidney to a stranger. Such donations meet the most stringent definitions of altruism in that they represent an intentional behavior that incurs significant costs to the donor to benefit an anonymous, nonkin other. Functional imaging and behavioral tasks included face-emotion processing paradigms that reliably distinguish psychopathic individuals from controls. Here we show that extraordinary altruists can be distinguished from controls by their enhanced volume in right amygdala and enhanced responsiveness of this structure to fearful facial expressions, an effect that predicts superior perceptual sensitivity to these expressions. These results mirror the reduced amygdala volume and reduced responsiveness to fearful facial expressions observed in psychopathic individuals. Our results support the possibility of a neural basis for extraordinary altruism. We anticipate that these findings will expand the scope of research on biological mechanisms that promote altruistic behaviors to include neural mechanisms that support affective and social responsiveness. PMID:25225374
Pankoke, Helga; Gehring, René; Müller, Caroline
Iridoid glycosides are plant defence compounds with potentially detrimental effects on non-adapted herbivores. Some plant species possess β-glucosidases that hydrolyse iridoid glycosides and thereby release protein-denaturing aglycones. To test the hypothesis that iridoid glycosides and plant β-glucosidases form a dual defence system, we used Plantago lanceolata and a polyphagous caterpillar species. To analyse the impact of leaf-age dependent differences in iridoid glycoside concentrations and β-glucosidase activities on insect performance, old or young leaves were freeze-dried and incorporated into artificial diets or were provided freshly to the larvae. We determined larval consumption rates and the amounts of assimilated nitrogen. Furthermore, we quantified β-glucosidase activities in artificial diets and fresh leaves and the amount of iridoid glycosides that larvae feeding on fresh leaves ingested and excreted. Compared to fresh leaves, caterpillars grew faster on artificial diets, on which larval weight gain correlated positively to the absorbed amount of nitrogen. When feeding fresh young leaves, larvae even lost weight and excreted only minute proportions of the ingested iridoid glycosides intact with the faeces, indicating that the hydrolysis of these compounds might have interfered with nitrogen assimilation and impaired larval growth. To disentangle physiological effects from deterrent effects of iridoid glycosides, we performed dual choice feeding assays. Young leaves, their methanolic extracts and pure catalpol reduced larval feeding in comparison to the respective controls, while aucubin had no effect on larval consumption. We conclude that the dual defence system of P. lanceolata consisting of iridoid glycosides and β-glucosidases interferes with the nutrient utilisation via the hydrolysis of iridoid glycosides and also mediates larval feeding behaviour in a concentration- and substance-specific manner. PMID:26306994
Heyttyey, Attila; Tóth, Zoltán; Buskirk, Josh
Phenotypic plasticity is extremely widespread in the behaviour, morphology and life-history of animals. However, inducible changes in the production of defensive chemicals are described mostly in plants and surprisingly little is known about similar plasticity in chemical defences of animals. Inducible chemical defences may be common in animals because many are known to produce toxins, the synthesis of toxins is likely to be costly, and there are a few known cases of animals adjusting their t...
Silk, Joan B; House, Bailey R
In this paper, we consider three hypotheses to account for the evolution of the extraordinary capacity for large-scale cooperation and altruistic social preferences within human societies. One hypothesis is that human cooperation is built on the same evolutionary foundations as cooperation in other animal societies, and that fundamental elements of the social preferences that shape our species' cooperative behaviour are also shared with other closely related primates. Another hypothesis is that selective pressures favouring cooperative breeding have shaped the capacity for cooperation and the development of social preferences, and produced a common set of behavioural dispositions and social preferences in cooperatively breeding primates and humans. The third hypothesis is that humans have evolved derived capacities for collaboration, group-level cooperation and altruistic social preferences that are linked to our capacity for culture. We draw on naturalistic data to assess differences in the form, scope and scale of cooperation between humans and other primates, experimental data to evaluate the nature of social preferences across primate species, and comparative analyses to evaluate the evolutionary origins of cooperative breeding and related forms of behaviour. PMID:26729936
"A field study of altruistic behaviour is presented using a modification of the dictator game in a large random sample survey in the Netherlands (n=1,964). In line with laboratory experiments, only 5.7% donated money. In line with other survey research on giving, generosity increased with age, education, income, trust, and prosocial value orientation." (author's abstract)
Full Text Available The dynamic behaviour of armour steel in tension was investigated over a wide range of strain-rates on round specimens. The experiments were carried out by means of a Split Hopkinson Tensile Bar device and by a Hydro Pneumatic Machine. The target strain rate were set at the following six levels: 10−3, 5, 25, 100, 500 and 1000 s−1. Two material models were calibrated and used to replicate the experiments and to simulate blasting event on steel plate. Finally, the two responses are compared.
Full Text Available This study aimed to examine how family income and social distance influence young rural Chinese children's altruistic behavior in the dictator game (DG. A total of 469 four-year-old children from eight rural areas in China, including many children left behind by parents who had migrated to urban areas for work, played the DG. Stickers comprised the resource, while recipients in the game were assumed to be either their friends or strangers, with the social distance (i.e., strangers compared to friends as a between-subjects variable. Children donated significantly more stickers to their friends than to strangers. Moreover, children from lower income families donated more stickers than children from higher income families. However, no gender and parental migrant status differences in children's prosocial behaviors were evident in this sample. Findings of this study suggest that children's altruistic behaviours to peers are influenced by family characteristics since preschool age. The probable influence of local socialization practices on development and the possible adaptive significance were discussed.
Van Zyl, Liezl; Walker, Ruth
It has become common to distinguish between altruistic and commercial contract motherhood (or 'surrogacy'). Altruistic arrangements are based on the 'gift relationship': a woman is motivated by altruism to have a baby for an infertile couple, who are free to reciprocate as they see fit. By contrast, in commercial arrangements both parties are motivated by personal gain to enter a legally enforceable agreement, which stipulates that the contract mother or 'surrogate' is to bear a child for the intending parents in exchange for a fee. She is required to undergo medical examinations and to refrain from behaviour that could harm the foetus. The intending parents are the child's legal parents from the outset. The parties to the contract can, but are not expected to, maintain contact after the transaction is completed. We argue that contract motherhood should not be organized according to the norms of the gift relationship, and that contract mothers should be compensated for their labour. However, we accept that there are good reasons for rejecting the commercial model as a suitable framework for contract pregnancy, and argue, instead, in favour of viewing it as a profession. PMID:22500585
We examine the classical contents of quantum games. It is shown that a quantum strategy can be interpreted as a classical strategies with effective density-dependent game matrices composed of transposed matrix elements. In particular, successful quantum strategies in dilemma games are interpreted in terms of a symmetrized game matrix that corresponds to an altruistic game plan.
Some observations on the nature of altruistic behavior and the consequences of these observations for a theoretical and experimental psychology of altruism are discussed. Altruistic behaviors are very pervasive since they satisfy a wide array of egotistical motivations in addition to having an autonomy of their own. Because of their ability to…
DESIDOC functions as a central agency of Defence Research & Development Organization (DRDO) for collecting, processing and disseminating scientific and technical information for the scientists and Technologists of the Organization in particular and the Ministry of Defence in general. The Centre aims to meet the current and futuristic information requirements of these personnel. The task of gathering information for high-tech Defence projects requires trained information scientists having ...
DESIDOC functions as a central agency of Defence Research & Development Organization (DRDO) for collecting, processing and disseminating scientific and technical information for the scientists and Technologists of the Organization in particular and the Ministry of Defence in general. The Centre aims to meet the current and futuristic information requirements of these personnel. The task of gathering information for high-tech Defence projects requires trained information scientists having suff...
Pavia, Henrik; Baumgartner, Finn; Cervin, Gunnar;
This chapter focuses on the recent and emerging research involving chemical defences against herbivory in aquatic primary producers. It provides an overview of plant chemical defence theories and highlights recent research on aquatic primary producers addressing a number of aspects of these...
The high radiosensitivity to killing of undifferentiated primordial cells (Bergonie and Tribondeau 1906) can be described as a manifestation of the suicide of injured cells for the benefit of an organism as a whole if their suicide stimulates proliferation of healthy cells to replace them, resulting in complete elimination of injury. This process is called cell-replacement repair, to distinguish it from DNA repair which is rarely complete. 'Cell suicide', 'programmed death' and 'apoptosis' are terms used for the same type of active cell death. Cell suicide is not always altruistic. Altruistic suicide in Drosophila, mice, humans, plants, and E. coli is reviewed in this paper to illustrate its widely different facets. The hypothesis that in animals, radiation hormesis results from altruistic cell suicide is proposed. This hypothesis can explain the hormetic effect of low doses of radiation on the immune system in mice. In contrast, in plants, radiation hormesis seems to be mainly due to non-altruistic cell death. (author)
Egas, Martijn; Riedl, Arno
Explaining the evolution and maintenance of cooperation among unrelated individuals is one of the fundamental problems in biology and the social sciences. Recent experimental evidence suggests that altruistic punishment is an important mechanism to maintain cooperation among humans. In this paper we explore the boundary conditions for altruistic punishment to maintain cooperation by systematically varying the cost and impact of punishment, using a subject pool which extends beyond the standar...
We address two issues that puzzled moral and socio-economic thinking since antiquity. The first of the puzzles is the emergence and selection fitness of altruist behavior in a world of self-reproducing individuals (or capital,etc.; memes in general). The second is the sustainability of growth and the survival in a stochastic world where along with large gains individuals incur often very large and even total losses. We show that the solution for each of these puzzles lies within the other one. It is known that in a multiplicative random process even if in the mathematical evaluation of the expected gain the wins overwhelm the losses, one is likely to be faced with extinction. For example if the probability of a total loss event is arbitrarily small but finite, the measure of histories with non-vanishing gains approaches 0 for asymptotic times >. Thus the optimistic theoretical expectation is dominated by event chains whose probability is too small to happen in reality. We find that in those situations, there ...
Groot, Judith Irene Maria de
Many scholars have emphasized the importance of studying human values when explaining prosocial behaviours. They distinguished between altruistic and egoistic value orientations. Altruistic value orientations emphasize that individuals are motivated to act prosocially to benefit others. Egoistic value orientations stress the importance of benefiting yourself when acting prosocially. In literature on environmental ethics, various scholars suggested that a third, “biospheric”, value orientation...
Li, Yiyuan; Li, Hong; Decety, Jean; Lee, Kang
Altruism is thought to be a major contributor to the development of large-scale human societies. However, much of the evidence supporting this belief comes from individuals living in pacific and often affluent environments. It is entirely unknown whether humans act altruistically when facing adversity. Adversity is arguably a common human experience (as manifested in, e.g., personal tragedies, political upheavals, and natural disasters). In the research reported here, we found that experiencing a natural disaster affected children's altruistic giving. Immediately after witnessing devastations caused by a major earthquake, 9-year-olds became more altruistic. In addition, the more empathic they were, the more they gave. In contrast, experiencing a major earthquake caused 6-year-olds to be more selfish. Three years after the earthquake, children's altruistic tendencies returned to pre-earthquake levels, which suggests that changes in children's altruistic giving are an acute response to the immediate aftermath of a major natural disaster. These findings suggest that environmental insults and empathy play crucial roles in human altruism. PMID:23842959
This paper explores the specific criticism of directed altruistic living organ donation that it creates a 'beauty contest' between potential recipients of organs. The notion of the beauty contest in transplantation was recently used by Neidich et al who stated that '[a]ltruism should be the guiding motivation for all donations, and when it [is], there is no place for a beauty contest'. I examine this beauty contest objection from two perspectives. First, I argue that, when considered against the behaviour of donors, this objection cannot be consistently raised without also objecting to other common aspects of organ donation. I then explore the beauty contest objection from the perspective of recipients, and argue that if the beauty contest is objectionable, it is because of a tension between recipient behaviour and the altruism that supposedly underpins the donation system. I conclude by briefly questioning the importance of this tension in light of the organ shortage. PMID:26126975
Fetchenhauer, Detlef; Groothuis, Ton; Pradel, Julia
Humans behave altruistically in one-shot interactions under total anonymity. In search of explanations for such behavior, it has been argued that at least some individuals have a general tendency to behave altruistically independent of profitability. In fact, a stable altruistic trait would be adapt
Pradel, Julia; Euler, Harald A.; Fetchenhauer, Detlef
Altruism can evolve through assortation if the selfish advantage of egoistic individuals is outcompeted by the benefits of mutual cooperation between altruists. This selection process is possible if (a) individuals can distinguish altruists from egoists and (b) altruists cooperate electively with ot
National defence is very important and always needs new such materials which have technological and socio-economic development of human society. The types of materials used by a society reflect its level of sophistication. These modern materials are basically the same conventional materials but with a greater knowledge content which include superalloys, modern polymers, engineering ceramics and the advanced composite. The production and use of new materials is playing and important role in the recent development in the defence industry. (A.B.)
Jin, Ai-Hua; Israel, Mathilde R; Inserra, Marco C; Smith, Jennifer J; Lewis, Richard J; Alewood, Paul F; Vetter, Irina; Dutertre, Sébastien
Some venomous cone snails feed on small fishes using an immobilizing combination of synergistic venom peptides that target Kv and Nav channels. As part of this envenomation strategy, δ-conotoxins are potent ichtyotoxins that enhance Nav channel function. δ-Conotoxins belong to an ancient and widely distributed gene superfamily, but any evolutionary link from ancestral worm-eating cone snails to modern piscivorous species has not been elucidated. Here, we report the discovery of SuVIA, a potent vertebrate-active δ-conotoxin characterized from a vermivorous cone snail (Conus suturatus). SuVIA is equipotent at hNaV1.3, hNaV1.4 and hNaV1.6 with EC50s in the low nanomolar range. SuVIA also increased peak hNaV1.7 current by approximately 75% and shifted the voltage-dependence of activation to more hyperpolarized potentials from -15 mV to -25 mV, with little effect on the voltage-dependence of inactivation. Interestingly, the proximal venom gland expression and pain-inducing effect of SuVIA in mammals suggest that δ-conotoxins in vermivorous cone snails play a defensive role against higher order vertebrates. We propose that δ-conotoxins originally evolved in ancestral vermivorous cones to defend against larger predators including fishes have been repurposed to facilitate a shift to piscivorous behaviour, suggesting an unexpected underlying mechanism for this remarkable evolutionary transition. PMID:26156767
Full Text Available The genetic origins of altruism, defined here as a costly act aimed to benefit non-kin individuals, have not been examined in young children. However, previous findings concerning adults pointed at the arginine vasopressin receptor 1A (AVPR1A gene as a possible candidate. AVPR1A has been associated with a range of behaviors including aggressive, affiliative and altruistic phenotypes, and recently a specific allele (327 bp of one of its promoter region polymorphisms (RS3 has been singled out in particular. We modeled altruistic behavior in preschoolers using a laboratory-based economic paradigm, a modified dictator game (DG, and tested for association between DG allocations and the RS3 "target allele." Using both population and family-based analyses we show a significant link between lower allocations and the RS3 "target allele," associating it, for the first time, with a lower proclivity toward altruistic behavior in children. This finding helps further the understanding of the intricate mechanisms underlying early altruistic behavior.
Mathur, Vani A; Harada, Tokiko; Lipke, Trixie; Chiao, Joan Y
A central evolutionary challenge for social groups is uniting a heterogeneous set of individuals towards common goals. One means by which social groups form and endure is by endowing group members with extraordinary prosocial proclivities, such as ingroup love, towards other group members. Here we examined the neural basis of extraordinary empathy and altruistic motivation in African-American and Caucasian-American individuals using functional magnetic resonance imaging. Our results indicate that empathy for ingroup members is neurally distinct from empathy for humankind, more generally. People showed greater response within anterior cingulate cortex and bilateral insula when observing the suffering of others, but African-American individuals additionally recruit medial prefrontal cortex when observing the suffering of members of their own social group. Moreover, neural activity within medial prefrontal cortex in response to pain expressed by ingroup relative to outgroup members predicted greater empathy and altruistic motivation for one's ingroup, suggesting that neurocognitive processes associated with self identity underlie extraordinary empathy and altruistic motivation for members of one's own social group. Taken together, our findings reveal distinct neural mechanisms of empathy and altruistic motivation in an intergroup context and may serve as a foundation for future research investigating the neural bases of intergroup prosociality, more broadly construed. PMID:20302945
Kaplan, B S; Polise, K
A shortage of cadaveric donor kidneys has created waiting lists for patients on chronic dialysis. Despite many ethical issues, donor kidneys are obtained from cadavers, first-degree living relatives, second-degree relatives (uncles, aunts), emotionally related persons such as spouses, and non-genetic altruistic donors who have a close relationship with the recipient. Most centers do not accept kidneys from minors, persons who have no genetic or personal relationship with the recipient, organs offered by altruistic strangers, or those that are purchased. The pros and cons of using kidneys from donors who are altruistic strangers (donors who have no genetic or personal relationship with the recipient) are reviewed. It may seem that organ acquisition for renal transplantation has moved down a slippery slope from cadaver donors to living non-related but emotionally related donors. However, it can also be argued that the approach to obtaining kidneys has evolved with improvements in safety to the donor and an increasing shortage of organs. It may also be argued that the approach should evolve from a paternalistic physician-centered role to a position in which the patient has more autonomy in deciding whether or not to accept a kidney from an altruistic donor. PMID:10872197
'Trojan horses', 'logic bombs', 'armoured viruses' and 'cryptovirology' are terms recalling war gears. In fact, concepts of attack and defence drive the world of computer virology, which looks like a war universe in an information society. This war has several shapes, from invasions of a network by worms, to military and industrial espionage ...
Full Text Available The NATO Defence Planning Process (NDPP is the most important element affecting the Alliance's defence posture. Under the process states commit themselves to provide capabilities and forces required to fulfil NATO missions, defined in the NATO Strategic Concept. The NDPP directly affects national defence plans by harmonizing them with identified security and defence objectives as well by influencing development of the novel national defence capabilities. The emergence of new threats in the NATO environment, demands modifications in the defense planning process and establishing new goals for the Alliance. Enhancement of the NDPP should be priority during the time of unrest.
Planqué, Robert; Britton, N. F.; Franks, N. R.; Peletier, M. A.
Most bird species of the Eurasian Cuckoo, 'Cuculuscanorus', often display egg-discrimination behaviour butchick-rejection behaviour has never been reported.In this paper, we analyse ahost-cuckoo association in which both population dynamics andevolutionary dynamics are explored in a discrete-time model.We introduce four host types, each with their own defence behaviour, displayingeither egg or chick rejection, neither or both. We also introducefitness functions for each of these host types.Al...
Within the Defence, Safety & Security branch of TNO a dedicated department focuses on Chemical, Biological, Radiological and Nuclear (CBRN) Protection. This is a world class research department consisting of about 50 people and a High Tox laboratory that is the only facility in The Netherlands that is allowed by the Chemical Weapons Treaty to produce and handle Chemical Warfare Agents (CWA’s). The CBRN department has a laboratory facility for synthesis of and working with live CWA’s or Toxic ...
P. V.S. Rao
Full Text Available With man's mastery over the third dimension - the near atmosphere and space- it has become increasingly necessary to protect oneself not merely from attacks from land and the sea but, more importantly, from attacks from the air. This was recognised even during the World War II and a rudimentary air defence capability was sought to be established; by the manul (visual surveillance and the anti-aircraft guns. The advent of radar signified a major advance in air defence technology and techniques. Rather than depend on visual observation and the hazards and limitations thereof, it became possible with radar to detect the presence of flying objects at much great distances. The PPI display of a conventional air-surveillance radar permits an operator to scan the sky for several hundreds of kilometers all around. Early radar-based air defence systems were dependent on human observation and decision making for detecting targets, identifying them, deciding on interception strategy and for recovering the interceptor after completion of his mission. This was feasible because, with a radar of between 200 to 400 kilometers and aircraft speeds in the range of 500 kilometers per hour, upto 30 minutes warning was available before the target was overhead.
We study an overlapping generations economy with altruistic agents in which the productivity of a child?s labour endowment depends on an idiosyncratic shock and on the resources spent by her parent in education her. The parent cannot borrow but can leave a nonnegative bequest which earns a deterministic return in the capital market; this possibility mitigates the liquidity constraint faced by an agent when deciding on the level of education for her child. The shock is assumed to follow a Mark...
This paper analyzes an evolutionary version of the Public Good game in which boundedly rational agents can use imitation and best-reply decision rules. Several possibilities for both decision rules to be present in the population are considered. I show that altruistic behavior might survive if switching between the decision rules occurs less often than the probabilities of errors in choosing a strategy and if local neighborhoods are not too small or too large.
P. K. Bhatnagar
Full Text Available Reviews the current status of radioisotope applications in Defence- R&D Establishments, Defence Inspectorates, Ordnance Factories, Public Sector Undertakings under the Defence Ministry, Army, Navy and Air Force Establishments and Military Hospitals. It also lists the users of film badge service in Defence. Training programmes in radioisotope applications in Defence conducted by DRDO organisations have also been highlighted.
Conclusions: We showed that altruistic decisions probe residual sgACC hypersensitivity in MDD even after symptoms are fully remitted. The sgACC has previously been shown to be associated with guilt which promotes altruistic decisions. In contrast, the striatum showed common activation to both simple and altruistic rewards and could be involved in the so-called “warm glow” of donation. Enhanced neural response in the depression group, in areas previously linked to altruistic decisions, supports the hypothesis of a possible association between hyper-altruism and depression vulnerability, as shown by recent epidemiological studies.
Altruism and the ethical relationship to other people affect behaviour of subjects in economic environment. Economy tries to capture this behaviour, there are various models, but it hasn´t been successful in fi nding one model describing various types and cases of altruistic behaviour. Business ethics faces a similar problem as it lacks a defi nition of what exactly ethical behaviour means. This paper claims impossibility of fi nding a unanimous defi nition belongs to ethics and is its charac...
de Groot, Judith I. M.; Steg, Linda
Various scholars argue that egoistic, altruistic, and biospheric value orientations are important for understanding environmental beliefs and behavior. However, little empirical evidence has been provided for the distinction between altruistic and biospheric values. This study examines whether this
The aim of this research is to determine the impact of school managers' altruist behaviors upon organizational cynicism by examining the relationship between school managers' altruist behaviors according to teachers and teachers' perceptions of organizational cynicism. The research sample consisted of 250 teachers employed in 15…
Ruiz-Olivares, Rosario; Pino, M. Jose; Herruzo, Javier
The aim of this study is to evaluate the differences in prosocial altruistic behavior between children and young students who belong to the scout movement and those who do not belong to this or any other similar movement. The prosocial altruistic behavior has been assessed with questionnaires for the school: self-evaluation, teacher, classmate,…
Kash, Ian A; Halpern, Joseph Y
We discuss the design of efficient scrip systems and develop tools for empirically analyzing them. For those interested in the empirical study of scrip systems, we demonstrate how characteristics of agents in a system can be inferred from the equilibrium distribution of money. From the perspective of a system designer, we examine the effect of the money supply on social welfare and show that social welfare is maximized by increasing the money supply up to the point that the system experiences a ``monetary crash,'' where money is sufficiently devalued that no agent is willing to perform a service. We also examine the implications of the presence of altruists and hoarders on the performance of the system. While a small number of altruists may improve social welfare, too many can also cause the system to experience a monetary crash, which may be bad for social welfare. Hoarders generally decrease social welfare but, surprisingly, they also promote system stability by helping prevent monetary crashes. In addition...
Bode, Nikolai W.F.; Jordan Miller; Rick O’Gorman; Edward A. Codling
Altruistic behaviour is widespread and highly developed in humans and can also be found in some animal species. It has been suggested that altruistic tendencies can depend on costs, benefits and context. Here, we investigate the changes in the occurrence of helping behaviour in a computer-based experiment that simulates an evacuation from a building exploring the effect of varying the cost to help. Our findings illuminate a number of key mechanistic aspects of human decision-making about whet...
Sharma, T. R.
"The Defence Food Research Laboratory, Mysore, is a major centre of research in India, particularly in defence feeding. It is multi-disciplinary laboratory, well equipped to do research work in food technology, food preservation, packaging, nutrition and biochemistry and food microbiology. Special emphasis is laid on development of light weight processed food suiting Indian palate. This paper gives a bird's eye view of the activities and achievements of the laboratory and indicates the...
Full Text Available This essay presents an extended defence of the general theory of law formulated by the Bolshevik jurist, Evgeny Pashukanis, and published in his Law and Marxism: A General Theory in 1924. The general theory is a theory of the legal form. Although Pashukanis did not name his theory, it has become known as the commodity form theory of law because of its theorising the legal form as a homologue of the commodity form. However, despite having weighty Marxist and revolutionary Bolshevik credentials, the general theory has been subjected to sustained attack, especially from new left and neo-Marxist circles. This essay identifies and explicates six major objections to Pashukanism from its left critics. These are that the general theory is too abstract to comprehend the reality of legal relations; that it is infused with economic reductionism; that it derives the legal form wrongly from commodity exchange; that it classifies the legal form incorrectly as an attribute of capitalism only; that it lacks the generality required of a general theory of law; and that it is imbricated in the growth of anarchism and Stalinism. Following a brief exegetical exercise, the bulk of the essay is devoted to demonstrating in detail that each of the six objections to the general theory is without merit, and that none makes any serious incursion into its integrity as a theory of the legal form. The central submission of the essay is that the Pashukanist general theory of law is rooted in the first principles of classical Marxism and hence may lay claim legitimately to being the Marxist theory of law.
Rajhans, Purva; Altvater-Mackensen, Nicole; Vaish, Amrisha; Grossmann, Tobias
Altruistic behavior in humans is thought to have deep biological roots. Nonetheless, there is also evidence for considerable variation in altruistic behaviors among individuals and across cultures. Variability in altruistic behavior in adults has recently been related to individual differences in emotional responsiveness to fear in others. The current study examined the relation between emotional responsiveness (using eye-tracking) and altruistic behavior (using the Dictator Game) in 4 to 5-year-old children (N = 96) across cultures (India and Germany). The results revealed that increased altruistic behavior was associated with a greater responsiveness to fear faces (faster fixation), but not happy faces, in both cultures. This suggests that altruistic behavior is linked to our responsiveness to others in distress across cultures. Additionally, only among Indian children greater altruistic behavior was associated with greater sensitivity to context when responding to fearful faces. These findings further our understanding of the origins of altruism in humans by highlighting the importance of emotional processes and cultural context in the development of altruism. PMID:27137754
Rajhans, Purva; Altvater-Mackensen, Nicole; Vaish, Amrisha; Grossmann, Tobias
Altruistic behavior in humans is thought to have deep biological roots. Nonetheless, there is also evidence for considerable variation in altruistic behaviors among individuals and across cultures. Variability in altruistic behavior in adults has recently been related to individual differences in emotional responsiveness to fear in others. The current study examined the relation between emotional responsiveness (using eye-tracking) and altruistic behavior (using the Dictator Game) in 4 to 5-year-old children (N = 96) across cultures (India and Germany). The results revealed that increased altruistic behavior was associated with a greater responsiveness to fear faces (faster fixation), but not happy faces, in both cultures. This suggests that altruistic behavior is linked to our responsiveness to others in distress across cultures. Additionally, only among Indian children greater altruistic behavior was associated with greater sensitivity to context when responding to fearful faces. These findings further our understanding of the origins of altruism in humans by highlighting the importance of emotional processes and cultural context in the development of altruism. PMID:27137754
Heilman, Madeline E; Chen, Julie J
In 2 experimental studies, the authors hypothesized that the performance of altruistic citizenship behavior in a work setting would enhance the favorability of men's (but not women's) evaluations and recommendations, whereas the withholding of altruistic citizenship behavior would diminish the favorability of women's (but not men's) evaluations and recommendations. Results supported the authors' predictions. Together with the results of a 3rd study demonstrating that work-related altruism is thought to be less optional for women than for men, these results suggest that gender-stereotypic prescriptions regarding how men and women should behave result in different evaluative reactions to the same altruistic behavior, depending on the performer's sex. PMID:15910140
Full Text Available The concept of organizational citizen behaviour (OCB has grown in popularity in the literature, and has received a great deal of theoretical and empirical study. However, various authors have emphasized the need of gaining a greater understanding of the antecedents of each dimension that makes up this construct, as few authors have focused on these aspects (Podsakoff et al., 2000. Hence, this study aims at analyzing the individualized consideration of leadership, the innovative organizational climate and the proactive personality, as possible antecedents of change-oriented and altruist organizational citizenship behaviors, by means of a revision and extension of the main studies that have dealt with such constructs. In this sense, the present study develops various propositions, derived from a conceptual model, whose aim is to advance the understanding related with OCB antecedents, so that future research can test them from an empirical point of view, using qualitative or quantitative methods.
Altruistic donation of organs from living donors is widely accepted as a virtue and even encouraged as a duty. Selling organs, on the other hand, is highly controversial and banned in most countries. What is the Jewish legal (halachic) position on these issues? In this review it is explained that altruistic donation is praiseworthy but in no way obligatory. Selling organs is a subject of rabbinic dispute among contemporary authorities.
Jan B. Rosen
Full Text Available Moral decision making involves affective and cognitive functions like emotional empathy, reasoning and cognitive empathy/theory of mind (ToM, which are discussed to be subject to age-related alterations. Additionally, sex differences in moral decision making have been reported. However, age-related changes in moral decision making from early to late adulthood and their relation to sex and neuropsychological functions have not been studied yet.One hundred ninety seven participants (122 female, aged 19 to 86 years, were tested with a moral decision making task comprising forced choice everyday life situations in which an altruistic option that favors a socially accepted alternative had to be considered against an egoistic option that favors personal benefit over social interests. The percentage of altruistic decisions was analyzed. A structural equation model (SEM was calculated to test the hypothesis whether age and sex predict altruistic moral decision, and whether relevant neuropsychological domains mediate these hypothesized relationships.A significant relationship between age and moral decision making was found indicating more frequent altruistic decisions with increasing age. Furthermore, women decided more altruistically than men. The SEM showed that both age and sex are significant predictors of altruistic moral decision making, mediated by emotional empathy but not by reasoning. No cognitive empathy and ToM scores were correlated to age and moral decision-making at the same time and thus were not included in the SEM.Our data suggest that increasing age and female sex have an effect on altruistic moral decisions, but that this effect is fully mediated by emotional empathy. The fact that changes of moral decision making with age are mediated by emotional empathy can be interpreted in the light of the so-called positivity effect and increasing avoidance of negative affect in aging. The mediated sex effect might represent both biological
Rosen, Jan B.; Brand, Matthias; Kalbe, Elke
Moral decision making involves affective and cognitive functions like emotional empathy, reasoning and cognitive empathy/theory of mind (ToM), which are discussed to be subject to age-related alterations. Additionally, sex differences in moral decision making have been reported. However, age-related changes in moral decision making from early to late adulthood and their relation to sex and neuropsychological functions have not been studied yet. One hundred ninety seven participants (122 female), aged 19–86 years, were tested with a moral decision making task comprising forced choice “everyday life” situations in which an altruistic option that favors a socially accepted alternative had to be considered against an egoistic option that favors personal benefit over social interests. The percentage of altruistic decisions was analyzed. A structural equation model (SEM) was calculated to test the hypothesis whether age and sex predict altruistic moral decision, and whether relevant neuropsychological domains mediate these hypothesized relationships. A significant relationship between age and moral decision making was found indicating more frequent altruistic decisions with increasing age. Furthermore, women decided more altruistically than men. The SEM showed that both age and sex are significant predictors of altruistic moral decision making, mediated by emotional empathy but not by reasoning. No cognitive empathy and ToM scores were correlated to age and moral decision making at the same time and thus were not included in the SEM. Our data suggest that increasing age and female sex have an effect on altruistic moral decisions, but that this effect is fully mediated by emotional empathy. The fact that changes of moral decision making with age are mediated by emotional empathy can be interpreted in the light of the so-called “positivity effect” and increasing avoidance of negative affect in aging. The mediated sex effect might represent both biological aspects
Previous studies discussing cooperation employ the best decision that every player knows all information regarding the payoff matrix and selects the strategy of the highest payoff. Therefore, they do not discuss cooperation based on the altruistic decision with limited information (bounded rational altruistic decision). In addition, they do not cover the case where every player can submit his/her strategy several times in a match of the game. This paper is based on Ohdaira's reconsideration of the bounded rational altruistic decision, and also employs the framework of the prisoner's dilemma game (PDG) with sequential strategy. The distinction between this study and the Ohdaira's reconsideration is that the former covers the model of multiple groups, but the latter deals with the model of only two groups. Ohdaira's reconsideration shows that the bounded rational altruistic decision facilitates much more cooperation in the PDG with sequential strategy than Ohdaira and Terano's bounded rational second-best decision does. However, the detail of cooperation of multiple groups based on the bounded rational altruistic decision has not been resolved yet. This study, therefore, shows how randomness in the network composed of multiple groups affects the increase of the average frequency of mutual cooperation (cooperation between groups) based on the bounded rational altruistic decision of multiple groups. We also discuss the results of the model in comparison with related studies which employ the best decision. (paper)
Webster, R. Scott
In response to the lecture format coming under "attack" and being replaced by online materials and smaller tutorials, this paper attempts to offer not only a defence but also to assert that the potential value of the lecture is difficult to replicate through other learning formats. Some of the criticisms against lectures will be…
Suicide bombers are the most spectacular example of an impregnable morality toward one's own group that co-exists alongside a radical amorality toward members of another group. Suicide bombers carry out massacres with the utter conviction that they are acting in accordance with values associated with the greatest good. Suicidal attacks are conceived as a form of lethal altruism, a damaging drift from human cooperative tendencies and one that requires a detailed understanding. Strong altruism is a main component of a cluster of temperamental traits that may distinguish individuals with propensities to put themselves at the threshold of major progroupal sacrifices. Among all populations there will be pockets of extreme moralizing altruists willing to make high investments in others, investments involving great personal risk. A research framework is outlined to study other constitutionally based traits (dominance, boldness, aggressiveness, machiavellianism, narcissism, messianism, credulity/religiosity) that may also contribute to the different roles played by self-recruited members in combative cells that in turn are crucial for the ties they establish and the tactics employed. Individually oriented research may reveal profiles distinguishing between potential inducers and performers of martyrdom. As a rule, machiavellistic leaders do not usually squander their personal choices on group commitments; on the contrary, their gift for simulating altruism is used for individual gains. Potential martyrs, on the other hand, are by definition squanderers. Evidence accrued in recent years in fields going from behavioral economics to cognitive neuroimaging makes such an endeavor feasible. PMID:19580547
It is argued in this paper that in the affluent, industrial societies, environmental behaviours like recycling are typically classified within ""the domain of morality"" in people's minds. Intentions regarding these types of behaviours are not ba a thorough - conscious or unconscious - calculation...... of the balance of costs and benefits. Rather, they are a function of the person's moral beliefs, i.e., beliefs in what is the right or wrong thing to do. The paper gives a brief review of the literature with the intention of uncovering problems and shortcomings in the framework of the SEU-model and...... the Theory of Reasoned Action (TRA) with regard to understanding recycling behaviour. Further, examples of misleading policy conclusions are discussed suggested that within the framework of cognitive psychology, Schwartz's model of altruistic behaviour offers a more satisfying starting point for...
Pentzold, Stefan; Zagrobelny, Mika; Rook, Frederik;
, before and during feeding as well as during digestion, and at several levels such as the insects’ feeding behaviour, physiology and metabolism. Insect adaptations frequently circumvent or counteract the activity of the plant β-glucosidases, bioactivating enzymes that are a key element in the plant’s two......-component chemical defence. These adaptations include host plant choice, non-disruptive feeding guilds and various physiological adaptations as well as metabolic enzymatic strategies of the insect’s digestive system. Furthermore, insect adaptations often act in combination, may exist in both generalists and...... studies are suggested to investigate in detail how insect adaptations act in combination to overcome plant chemical defences and to allow ecologically relevant conclusions....
Ministry of Defence policy is to conform as closely as possible to UK health and safety legislation in all its operations. We consider the implications of the law and the guidance provided by the Health and Safety Executive for the arguments we need to make for the safety of defence procurements, and extract four general principles to help in answering the questions that arise when considering the safety of systems with complex behaviour. One of these principles is analysed further to identify how case law and the guidance interpret the requirement for risks to be reduced so far as is reasonably practicable. We then apply the principles to answer some questions that have arisen in our work as Independent Safety Auditors, including the limits to the tolerability of risk to armed forces personnel and civilians in wartime, and the acceptability of the transfer of risk from one group to another when controls on risk are introduced.
Full Text Available Interpretational tendencies in ambiguous situations were investigated as causal mechanisms of altruistic compensation. We used a training procedure to induce a tendency to interpret one’s own advantages as unjustified. In a subsequent mixed-game, participants had to decide whether to invest their own money to compensate a victim of a norm violation. The amount of one’s own resources invested as an altruistic compensation was enhanced after the training procedure compared to controls. These findings suggest that interpretational patterns with regard to injustice determine prosocial behavior. The training procedure offers a potential intervention strategy for enhancing altruistic compensation in bystander situations in which people must invest their own resources to restore justice.
Maltese, Simona; Baumert, Anna; Knab, Nadine; Schmitt, Manfred
Interpretational tendencies in ambiguous situations were investigated as causal mechanisms of altruistic compensation. We used a training procedure to induce a tendency to interpret one's own advantages as unjustified. In a subsequent mixed-game, participants had to decide whether to invest their own money to compensate a victim of a norm violation. The amount of one's own resources invested as an altruistic compensation was enhanced after the training procedure compared to controls. These findings suggest that interpretational patterns with regard to injustice determine prosocial behavior. The training procedure offers a potential intervention strategy for enhancing altruistic compensation in bystander situations in which people must invest their own resources to restore justice. PMID:24391614
Full Text Available In the reality of practical cases and in certain special situations, self-defence may present some complex forms consisting either in accidental amplification of the issue in fact when self-defence is claimed, or in the correlation in fact of self-defence to other cases which remove the criminal nature of act1. For these reasons, we decided to analyse few of such special situations.
Wilt, de, HGJ; Sluiter, G.K.; Temminck Tuinstra, J.P.W.
The field of international criminal law is relatively new and rapidly developing. This dissertation examines whether international criminal courts enable defence counsel to conduct an effective defence. When the International Criminal Tribunals for the former Yugoslavia and Rwanda (the ad hoc Tribunals) were set up in the mid-nineties to prosecute those responsible for serious violations of international humanitarian law, not much thought had been given to the organisation of the defence. The...
Garg, Rahul; Vogelgesang, Joseph; Kelly, Kimberly
Despite the importance of altruism in an individual's participation in genetic counseling and testing, little research has explored the change in altruistic motivations to test over time. This study analyzed altruistic motivations to test and change in altruistic motivations after genetic counseling and testing among individuals (N = 120) at elevated risk for BRCA1/2 mutations. The perceived benefits of genetic testing were assessed and utilized in a mixed-methods, repeated measures design at three time points: pre-counseling, counseling and post-genetic testing, along with transcripts of genetic counseling sessions. Qualitative analysis using an immersion/crystallization method resulted in six common perceived benefits of testing: cancer prevention, awareness, family's survival, relief from anxiety, for science, and future planning. Perceived benefits were then coded into three categories according to Hamilton's kin selection theory: altruistic motivation, personal motivation, and motivation for mutual benefit. At pre-counseling, those with a personal cancer history (p = 0.003) and those with one or more children (p = 0.013), were significantly more likely to cite altruistic motivations to test. Altruistic motivations significantly increased post-counseling (p = 0.01) but declined post-testing (p cancer to have altruistic motivations for testing. Genetic counseling may have increased altruistic motivations to help family and may be a prime opportunity to discuss other forms of altruism. PMID:26578231
Full Text Available One of the handiest small craft to emerge from the Second World War was the 72 fet Harbour Defence Motor Launch. It's purpose was to patrol harbours and their approaches and to guard against attack by swimmers or underwater vehicles such as 'chariots' or even submarines. For this task the craft was fitted with a small ASDIC outfit and carried eight depth charges. Surface armament comprised a three-pounder gun on the foredeck, twin Lewis guns on the bridge and a 20 mm Oerlikon aft.
Schaub Jr, Gary John
, Sweden, and Finland—have conducted joint training courses for decades and are considering ways to facilitate cooperation in the education of the field-grade officers that would populate the staff of any future NATO-led expeditionary operation. We suggest three alternative paths that increased cooperation...... in PME at the level of the command and staff course could take: a Nordic Defence College, standardized national command and staff courses, and a core curriculum of common courses for common purposes. We conclude with a discussion of how the Alliance can facilitate clusters of cooperation between...
Stefan Pentzold; Mika Zagrobelny; Pernille Sølvhøj Roelsgaard; Birger Lindberg Møller; Søren Bak
Cyanogenic glucosides (CNglcs) are widespread plant defence compounds that release toxic hydrogen cyanide by plant bglucosidaseactivity after tissue damage. Specialised insect herbivores have evolved counter strategies and some sequesterCNglcs, but the underlying mechanisms to keep CNglcs intact during feeding and digestion are unknown. We show thatCNglc-sequestering Zygaena filipendulae larvae combine behavioural, morphological, physiological and biochemicalstrategies at different time point...
Mahr, Katharina; Riegler, Georg; Hoi, Herbert
Do parents defend their offspring whenever necessary, and do self-sacrificing parents really exist? Studies recognized that parent defence is dynamic, mainly depending on the threat predators pose. In this context, parental risk management should consider the threat to themselves and to their offspring. Consequently, the observed defence should be a composite of both risk components. Surprisingly, no study so far has determined the influence of these two threat components on parental decision rules. In a field experiment, we investigated parental risk taking in relation to the threat posed to themselves and their offspring. To disentangle the two threat components, we examined defence behaviours of parent blue tits Cyanistes caeruleus towards three different predators and during different nestling developmental stages. Nest defence strategies in terms of alarm call intensity and nearest predator approach differed between the three predators. Defence intensity was only partly explained by threat level. Most importantly, parental risk management varied in relation to their own, but not offspring risk. Parent defence investment was independent of nestling risk when parents followed a high-risk strategy. However, parents considered nestling as well as parental risk when following a low-risk strategy. Our findings could have general implications for the economy of risk management and decision-making strategies in living beings, including humans. PMID:25392467
Patel, Shaneel Rajendra; Chadha, Priyanka; Papalois, Vassilios
In renal transplant, there is a well-known deficiency in organ supply relative to demand. Live donation provides superior results when compared with deceased donation including a better rate of graft success and fewer immunologic complications. This deficiency in organs leads to significant morbidity and mortality rates. Alternative avenues have been extensively explored that may expand the live donor pool. They include altruistic donation as well as paired and pooled exchange programs. Altruistic donation is a truly selfless act from a donor unknown to the recipient. Kidney paired donation involves 2 incompatible donor-recipient pairs swapping donors to produce compatibility. Pooled donation involves at least 2 pairs, and can take the form of domino chains in which altruistic input sets up a chain of transplants, in which each recipient's incompatible donor makes a donation for the next recipient. Despite application of these various methods, there lie extensive ethical issues surrounding them. Misconceptions frequently occur; for instance, the perceived benefit that donating an organ to a loved one is greater for a related donor than for an altruistic one. Additionally, it is frequently believed that immunologic incompatibility offers coerced donors liberation from surgery, and that overcoming these barriers by introducing exchange programs provides vulnerable donors less protection. This article explores these and other complex ethical issues surrounding the various methods of expanding the donor pool. The authors offer opinions that challenge the ethical issues and attempt to overcome those views that hinder progress in the field. PMID:21649566
Weisgram, Erica S.; Bigler, Rebecca S.
Two studies examined the roles of altruistic values, egalitarianism, self-efficacy, and perceptions of utility in shaping children's interest in scientific fields. In Study 1, middle school girls attending an intervention program ("n"=617) heard presentations by female scientists (expected to increase egalitarianism), engaged in hands-on science…
Friedman, Isaac A.
The article focuses on investigating pre-service teachers' expectations of their future teaching career, in particular concerning teacher-student interrelations. In an attempt to comprehend why people choose teaching as a professional career, a conceptual model titled "Teachers" altruistic-narcissistic classroom expectations' was…
Drakulich, Kevin M
While the vast majority of research on the causes and consequences of fear of crime has been focused on personal fears, Warr and Ellison have suggested that fears for one's family are both more common and more important in explaining protective actions like gun ownership. The present work not only provides new evidence supporting these findings but also expands our understanding of altruistic fears in two important directions: by exploring the potential sources of such fears in exposure to crime and by exploring new potential responses to such fears, including residential mobility decisions. The results suggest that altruistic fears are rooted in personal experiences with victimization and personal evaluations of the local danger posed by crime-though the ways that people react to victimizations depend on their opportunities for personal versus altruistic fears. In turn, altruistic fears are associated with taking protective measures, withdrawing from local organizational participation, and the desire and intent to flee neighborhoods altogether. However, the article also acknowledges important independent roles for personal fears and cognitive evaluations of danger, ultimately recommending a more holistic perspective on reactions to crime. PMID:25001615
In 2009 the United States invested in defence R&T 3,6 times and in defence research and development 6,8 times as much as all member states of the European Defence Agency (EDA) combined while the ratio in the total defence expenditure was 2,6 in the US' favour. The European lack of investments in defence research and development has a negative impact on the competitiveness of European defence industry and on the European non-dependence. In addition, the efficiency of investment is reduced due to duplication of work in different member states. The Lisbon Treaty tasks EDA to support defence technology research, and coordinate and plan joint research activities and the study of technical solutions meeting future operational needs. This paper gives an overview how EDA meets the challenge of improving the efficiency of European defence R&T investment with an emphasis on electro-optics and describes shortly the ways that governmental and industrial partners can participate in the EDA cooperation. Examples of joint R&T projects addressing electro-optics are presented.
J.P.W. Temminck Tuinstra
The field of international criminal law is relatively new and rapidly developing. This dissertation examines whether international criminal courts enable defence counsel to conduct an effective defence. When the International Criminal Tribunals for the former Yugoslavia and Rwanda (the ad hoc Tribun
Full Text Available A más fajok fiókáit etető madarakról számos beszámolót publikáltak az ornitológiai szakirodalomban. Azonban evolúciós szempontból az ilyen altruisztikus viselkedés értelmezése nehéz feladat, ugyanis az önzetlen egyed számára a viselkedés előnye még kevéssé ismert. Egy közép-olaszországi (Piana Fiorentina, Toszkána vizes élőhelyen 2013 májusában több alkalommal megfigyeltük, hogy szárcsa (Fulica atra fiókát etetett egy kifejlett, de nem költő fattyúszerkő (Chlidonias hybrida. Véleményünk szerint a szerkő viselkedését a szárcsa fióka kéregetése, vagy a saját hormonális állapota válthatta ki.
The technical requirements for the radiation meters used in civil defence are specified in the guide. The aim of the requirements is to quarantee sufficient measurement accuracy and reliable operation even in extreme environmental conditions. The guide is based on the following standards: (1) IEC 846 'Beta, X and gamma radiation dose equivalent and dose equivalent rate meters for use in radiation protection', (2) IEC 1017-1 'Portable, transportable of installed X or gamma radiation ratemeters for environmental monitoring, part 1: Ratemeters', and (3) IEC 45 B (Secretariat) 104 'Direct reading, personnel dose equivalent and/or dose equivalent rate monitors for X, gamma and high energy beta radiation'. (12 refs., 5 tabs.)
This article is about the network security defence method and technique at IHEP. Including: the experience, research result and application in network outlet security, server security, local network security, network security monitoring and collecting evidence, anti-virus etc
T. Lazar Mathew
Full Text Available Biotechnology, in its present perspective, encompasses activities, such as recombination of genes; cloning, or making genetically identical copies of a living thing; and splicing of genes from DNA of one organism into the genome of unrelated species, to create new, self-reproducing forms of life. The vast potential of biotechnology is being increasingly realised, and efforts are in progress to harness it for improving quality and quantity of bio-weapons, The bio-weapons, as such, are highly attractive because of their non-detection by routine security systems, ease of access, low production cost and easy transportation, A wide range of genetically manipulated organisms and their by-products are considered to have an added advantage, because these genetically manipulated biologics not only accentuate the existing properties of bio-weapons, but also could be made target-specific. Biotechnology, if used prudently, can play a significant role to counter such threats of biologics, viz., by producing (i bio-armoury comprising powerful antibiotics, antisera toxoids and vaccines to neutralise and eliminate a wide range of diseases, and (ii bio-sensors for rapid detection, identification and neutralisation of biological warfare agents. This article elucidates some facets of biological warfare, legal protective strategies emphasised through international consultation, cooperation and adherence to the Biological and Toxin Weapons Convention, and discusses how biotechnology could be effectively used to strengthen countries' defence and combat the threat of biological warfare.
Lopez-Romero, G; Quintero, J; Astiazarán-García, H; Velazquez, C
Giardia spp. is a protozoan parasite that inhabits the upper small intestine of mammals and other species and is the aetiological agent of giardiasis. It has been demonstrated that nitric oxide, mast cells and dendritic cells are the first line of defence against Giardia. IL-6 and IL-17 play an important role during infection. Several cytokines possess overlapping functions in regulating innate and adaptive immune responses. IgA and CD4(+) T cells are fundamental to the process of Giardia clearance. It has been suggested that CD4(+) T cells play a double role during the anti-Giardia immune response. First, they activate and stimulate the differentiation of B cells to generate Giardia-specific antibodies. Second, they act through a B-cell-independent mechanism that is probably mediated by Th17 cells. Several Giardia proteins that stimulate humoral and cellular immune responses have been described. Variant surface proteins, α-1 giardin, and cyst wall protein 2 can induce host protective responses to future Giardia challenges. The characterization and evaluation of the protective potential of the immunogenic proteins that are associated with Giardia will offer new insights into host-parasite interactions and may aid in the development of an effective vaccine against the parasite. PMID:26072999
Schofield, Heather; Loewenstein, George; Kopsic, Jessica; Volpp, Kevin G
This study examines the impact of individually oriented, purely altruistic, and a hybrid of competitive and cooperative monetary reward incentives on older adults' completion of cognitive exercises and cognitive function. We find that all three incentive structures approximately double the number of exercises completed during the six-week active experimental period relative to a no incentive control condition. However, the altruistic and cooperative/competitive incentives led to different patterns of participation, with significantly higher inter-partner correlations in utilization of the software, as well as greater persistence once incentives were removed. Provision of all incentives significantly improved performance on the incentivized exercises. However, results of an independent cognitive testing battery suggest no generalizable gains in cognitive function resulted from the training. PMID:26595894
Schofield, Heather; Loewenstein, George; Kopsic, Jessica; Volpp, Kevin G.
This study examines the impact of individually oriented, purely altruistic, and a hybrid of competitive and cooperative monetary reward incentives on older adults’ completion of cognitive exercises and cognitive function. We find that all three incentive structures approximately double the number of exercises completed during the six-week active experimental period relative to a no incentive control condition. However, the altruistic and cooperative/competitive incentives led to different patterns of participation, with significantly higher inter-partner correlations in utilization of the software, as well as greater persistence once incentives were removed. Provision of all incentives significantly improved performance on the incentivized exercises. However, results of an independent cognitive testing battery suggest no generalizable gains in cognitive function resulted from the training. PMID:26595894
Indian defence aeronautical industry, while becoming a global business, demands a largeeffort to monitor quality management system (QMS) and to ensure quality of aeronauticalproducts. An effort is being made to look for an effective QMS for aeronautical industry in India,which will also meet the requirements of the regulatory authority.The essential features of an effective QMS are described and compared with the presentlyavailable QMS standards for defence aeronautical industry such as QCSR:...
Giebel, Gilda; Elbert, Thomas
Studies have reported the effects of imprisonment on the wives and girlfriends of prisoners, but have not investigated how these women perceive love and commitment. This study analyzes four different styles of love: eros (romantic love), storge (amicably love), mania (possessive love), and agape (altruistic love) in a sample of 96 women who are in relationships with prisoners. The same love styles were compared to a control sample of N=96 women. They were selected from a larger sample of 859 ...
Cremer, Helmuth; Roeder, Kerstin
We study exchanges between three overlapping generations with non-dynastic altruism. The middleaged choose informal care provided to their parents and education expenditures for their children. The young enjoy their education, while the old may leave a bequest to their children. Within each period the three generations play a “game” inspired by Becker's (1974, 1991) rotten kids framework, with the added features that the rotten kids turn into the altruistic parent in the next period and that ...
de C Williams, Amanda C; Gallagher, Elizabeth; Fidalgo, Antonio R; Bentley, Peter J
Predictions which invoke evolutionary mechanisms are hard to test. Agent-based modeling in artificial life offers a way to simulate behaviors and interactions in specific physical or social environments over many generations. The outcomes have implications for understanding adaptive value of behaviors in context. Pain-related behavior in animals is communicated to other animals that might protect or help, or might exploit or predate. An agent-based model simulated the effects of displaying or not displaying pain (expresser/nonexpresser strategies) when injured and of helping, ignoring, or exploiting another in pain (altruistic/nonaltruistic/selfish strategies). Agents modeled in MATLAB interacted at random while foraging (gaining energy); random injury interrupted foraging for a fixed time unless help from an altruistic agent, who paid an energy cost, speeded recovery. Environmental and social conditions also varied, and each model ran for 10,000 iterations. Findings were meaningful in that, in general, contingencies that evident from experimental work with a variety of mammals, over a few interactions, were replicated in the agent-based model after selection pressure over many generations. More energy-demanding expression of pain reduced its frequency in successive generations, and increasing injury frequency resulted in fewer expressers and altruists. Allowing exploitation of injured agents decreased expression of pain to near zero, but altruists remained. Decreasing costs or increasing benefits of helping hardly changed its frequency, whereas increasing interaction rate between injured agents and helpers diminished the benefits to both. Agent-based modeling allows simulation of complex behaviors and environmental pressures over evolutionary time. PMID:26655734
Erdem Pulcu; Roland Zahn; Jorge Moll; Trotter, Paula D.; Emma J. Thomas; Gabriella Juhasz; J.F.William Deakin; Anderson, Ian M; Sahakian, Barbara J.; Rebecca Elliott
Background: Major depressive disorder (MDD) is associated with functional abnormalities in fronto-meso-limbic networks contributing to decision-making, affective and reward processing impairments. Such functional disturbances may underlie a tendency for enhanced altruism driven by empathy-based guilt observed in some patients. However, despite the relevance of altruistic decisions to understanding vulnerability, as well as everyday psychosocial functioning, in MDD, their functional neuroanato...
Liu, Buyun; Huang, Zhelan; Xu, Guifeng; Jin, Yu; Chen, Yajun; Li, Xiuhong; Wang, Qingxiong; Song, Shanshan; Jing, Jin
This study aimed to assess altruistic sharing behavior in children aged 3 to 5, 6 to 8, and 9 to 11 years and to explore the involvement of potential cognitive mechanisms, namely theory of mind (ToM) and inhibitory control. A total of 158 children completed a dictator game with stickers as incentives. ToM was evaluated using a false belief task in preschoolers and the Strange Story Test in school-age children. Inhibitory control was assessed in preschoolers with the Day-Night task and in older children with the Stroop Color-Word Test. The result was that 48.10% of children aged 3 to 5 years decided to share, and the percentage rose significantly with increasing age. The difference in altruism level in children who decided to share among the three age groups was nonsignificant. These results suggest that mechanisms underlying the decision to share or not and altruistic behavior may be different. No significant linear relations were found between cognitive processes (i.e., ToM and inhibitory control) and sharing behavior. Surprisingly, 9- to 11-year-olds who shared 3 of 10 stickers performed worse in inhibitory control than did those who shared any other number of stickers. In conclusion, the proportion of children who decided to share, but not the level of altruism, increased with age. ToM was not involved in altruistic sharing, whereas inhibitory control may play a role when deciding how much to share. PMID:26452508
Bakker, Gary Maria
Thought stopping (TS) has a long and established history as an effective mental control technique among the cognitive behavioural therapies (CBT). Recent claims have arisen, particularly from acceptance and mindfulness-based authors, that thought suppression--and therefore TS--is counterproductive. These claims take the syllogistic form: TS is a…
Fanny Mondet; Seo Hyun Kim; Joachim R. de Miranda; Dominique Beslay; Yves Le Conte; Mercer, Alison R.
Social immunity forms an essential part of the defence repertoire of social insects. In response to infestation by the parasitic mite Varroa destructor and its associated viruses, honey bees (Apis mellifera L.) have developed a specific behaviour (varroa-sensitive hygiene, or VSH) that helps protect the colony from this parasite. Brood cells heavily infested with mites are uncapped, the brood killed, and the cell contents removed. For this extreme sacrifice to be beneficial to the colony, the...
Noret,Nausicaa; Meerts, Pierre Jacques; Vanhaelen, Mathieu; Dos Santos, Anabelle; Escarre Blanch, José
Some plant species growing on metalliferous soils are able to accumulate heavy metals in their shoots up to very high concentrations, but the selective advantage of this behaviour is still unknown. The most popular hypothesis, that metals protect plants against herbivores, has been tested several times in laboratory conditions, with contradictory results. We carried out the first large-scale test of the defence hypothesis in eight natural populations of the model Zn hyperaccumulator Thlaspi c...
Full Text Available In his book 'The Normative Web' Terence Cuneo provides a core argument for a paradigmatic instance of moral realism. At the heart of this instance lies the ontological thesis that there are irreducible moral facts. The parity premise is the first and main premise of Cuneo's core argument. It claims that 'if moral facts do not exist, then epistemic facts do not exist'. In this paper I first introduce and explain Cuneo's core argument. Subsequently I present and interpret his defence of the parity premise. It will be shown that Cuneo's defence, although intriguing, is not adequate and should therefore be refuted.
Récapet, Charlotte; Daniel, Grégory; Taroni, Joëlle; Bize, Pierre; Doligez, Blandine
Dispersing and non-dispersing individuals often differ in phenotypic traits (e.g. physiology, behaviour), but to what extent these differences are fixed or driven by external conditions remains elusive. We experimentally tested whether differences in nest-defence behaviour between dispersing and non-dispersing individuals changed with local habitat quality in collared flycatchers, by providing additional food during the nestling rearing period. In control (non-food-supplemented) nests, dispersers were less prone to defend their brood compared with non-dispersers, whereas in food-supplemented nests, dispersing and non-dispersing individuals showed equally strong nest defence. We discuss the importance of dispersal costs versus adaptive flexibility in reproductive investment in shaping these differences in nest-defence behaviour between dispersing and non-dispersing individuals. Irrespective of the underlying mechanisms, our study emphasizes the importance of accounting for environmental effects when comparing traits between dispersing and non-dispersing individuals, and in turn assessing the costs and benefits of dispersal. PMID:27194287
Full Text Available BACKGROUND: Many animals reduce the risk of being attacked by a predator through crypsis, masquerade or, alternatively, by advertising unprofitability by means of aposematic signalling. Behavioural attributes in prey employed after discovery, however, signify the importance of also having an effective secondary defence if a predator uncovers, or is immune to, the prey's primary defence. In butterflies, as in most animals, secondary defence generally consists of escape flights. However, some butterfly species have evolved other means of secondary defence such as deimatic displays/startle displays. The European swallowtail, Papilio machaon, employs what appears to be a startle display by exposing its brightly coloured dorsal wing surface upon disturbance and, if the disturbance continues, by intermittently protracting and relaxing its wing muscles generating a jerky motion of the wings. This display appears directed towards predators but whether it is effective in intimidating predators so that they refrain from attacks has never been tested experimentally. METHODOLOGY/PRINCIPAL FINDINGS: In this study we staged encounters between a passerine predator, the great tit, Parus major, and live and dead swallowtail butterflies in a two-choice experiment. Results showed that the dead butterfly was virtually always attacked before the live butterfly, and that it took four times longer before a bird attacked the live butterfly. When the live butterfly was approached by a bird this generally elicited the butterfly's startle display, which usually caused the approaching bird to flee. We also performed a palatability test of the butterflies and results show that the great tits seemed to find them palatable. CONCLUSIONS/SIGNIFICANCE: We conclude that the swallowtail's startle display of conspicuous coloration and jerky movements is an efficient secondary defence against small passerines. We also discuss under what conditions predator-prey systems are likely to
Haas, Brian W; Brook, Michael; Remillard, Laura; Ishak, Alexandra; Anderson, Ian W; Filkowski, Megan M
The ability to empathize with other people is a critical component of human social relationships. Empathic processing varies across the human population, however it is currently unclear how personality traits are associated with empathic processing. This study was designed to test the hypothesis that specific personality traits are associated with behavioral and biological indicators of improved empathy. Extraversion and Agreeableness are personality traits designed to measure individual differences in social-cognitive functioning, however each trait-dimension includes elements that represent interpersonal social functioning and elements that do not represent interpersonal social functioning. We tested the prediction that interpersonal elements of Extraversion (Warmth) and Agreeableness (Altruism) are associated with empathy and non-interpersonal elements of Extraversion and Agreeableness are not associated with empathy. We quantified empathic processing behaviorally (empathic accuracy task using video vignettes) and within the brain (fMRI and an emotional perspective taking task) in 50 healthy subjects. Converging evidence shows that highly warm and altruistic people are well skilled in recognizing the emotional states of other people and exhibit greater activity in brain regions important for empathy (temporoparietal junction and medial prefrontal cortex) during emotional perspective taking. A mediation analysis further supported the association between warm-altruistic personality and empathic processing; indicating that one reason why highly warm-altruistic individuals may be skilled empathizers is that they engage the temporoparietal junction and medial prefrontal cortex more. Together, these findings advance the way the behavioral and neural basis of empathy is understood and demonstrates the efficacy of personality scales to measure individual differences in interpersonal social function. PMID:25769028
Brian W Haas
Full Text Available The ability to empathize with other people is a critical component of human social relationships. Empathic processing varies across the human population, however it is currently unclear how personality traits are associated with empathic processing. This study was designed to test the hypothesis that specific personality traits are associated with behavioral and biological indicators of improved empathy. Extraversion and Agreeableness are personality traits designed to measure individual differences in social-cognitive functioning, however each trait-dimension includes elements that represent interpersonal social functioning and elements that do not represent interpersonal social functioning. We tested the prediction that interpersonal elements of Extraversion (Warmth and Agreeableness (Altruism are associated with empathy and non-interpersonal elements of Extraversion and Agreeableness are not associated with empathy. We quantified empathic processing behaviorally (empathic accuracy task using video vignettes and within the brain (fMRI and an emotional perspective taking task in 50 healthy subjects. Converging evidence shows that highly warm and altruistic people are well skilled in recognizing the emotional states of other people and exhibit greater activity in brain regions important for empathy (temporoparietal junction and medial prefrontal cortex during emotional perspective taking. A mediation analysis further supported the association between warm-altruistic personality and empathic processing; indicating that one reason why highly warm-altruistic individuals may be skilled empathizers is that they engage the temporoparietal junction and medial prefrontal cortex more. Together, these findings advance the way the behavioral and neural basis of empathy is understood and demonstrates the efficacy of personality scales to measure individual differences in interpersonal social function.
Marco F H Schmidt
Full Text Available Human cooperation is a key driving force behind the evolutionary success of our hominin lineage. At the proximate level, biologists and social scientists have identified other-regarding preferences--such as fairness based on egalitarian motives, and altruism--as likely candidates for fostering large-scale cooperation. A critical question concerns the ontogenetic origins of these constituents of cooperative behavior, as well as whether they emerge independently or in an interrelated fashion. The answer to this question will shed light on the interdisciplinary debate regarding the significance of such preferences for explaining how humans become such cooperative beings. We investigated 15-month-old infants' sensitivity to fairness, and their altruistic behavior, assessed via infants' reactions to a third-party resource distribution task, and via a sharing task. Our results challenge current models of the development of fairness and altruism in two ways. First, in contrast to past work suggesting that fairness and altruism may not emerge until early to mid-childhood, 15-month-old infants are sensitive to fairness and can engage in altruistic sharing. Second, infants' degree of sensitivity to fairness as a third-party observer was related to whether they shared toys altruistically or selfishly, indicating that moral evaluations and prosocial behavior are heavily interconnected from early in development. Our results present the first evidence that the roots of a basic sense of fairness and altruism can be found in infancy, and that these other-regarding preferences develop in a parallel and interwoven fashion. These findings support arguments for an evolutionary basis--most likely in dialectical manner including both biological and cultural mechanisms--of human egalitarianism given the rapidly developing nature of other-regarding preferences and their role in the evolution of human-specific forms of cooperation. Future work of this kind will help
Mothes, Hendrik; Enge, Sören; Strobel, Alexander
To date, the interplay betwexen neurophysiological and individual difference factors in altruistic punishment has been little understood. To examine this issue, 45 individuals participated in a Dictator Game with punishment option while the feedback-related negativity (FRN) was derived from the electroencephalogram (EEG). Unlike previous EEG studies on the Dictator Game, we introduced a third party condition to study the effect of fairness norm violations in addition to employing a first person perspective. For the first time, we also examined the role of individual differences, specifically fairness concerns, positive/negative affectivity, and altruism/empathy as well as recipients' financial situation during altruistic punishment. The main results show that FRN amplitudes were more pronounced for unfair than for fair assignments in both the first person and third party perspectives. These findings suggest that FRN amplitudes are sensitive to fairness norm violations and play a crucial role in the recipients' evaluation of dictator assignments. With respect to individual difference factors, recipients' current financial situation affected the FRN fairness effect in the first person perspective, indicating that when being directly affected by the assignments, more affluent participants experienced stronger violations of expectations in altruistic punishment decisions. Regarding individual differences in trait empathy, in the third party condition FRN amplitudes were more pronounced for those who scored lower in empathy. This may suggest empathy as another motive in third party punishment. Independent of the perspective taken, higher positive affect was associated with more punishment behavior, suggesting that positive emotions may play an important role in restoring violated fairness norms. PMID:26530245
Fafoutis, Xenofon; Orfanidis, Charalampos; Dragoni, Nicola
In receiver-initiated medium access control (MAC) protocols for wireless sensor networks, communication is initiated by the receiver node which transmits beacons indicating its availability to receive data. In the case of multiple senders having traffic for a given receiver, such beacons form...... points where collisions are likely to happen. In this paper, we present altruistic backoff (AB), a novel collision avoidance mechanism that aims to avoid collisions before the transmission of a beacon. As a result of an early backoff, senders spend less time in idle listening waiting for a beacon, thus...
Living donation is becoming increasingly used to help fill the gap between the needs of potential organ recipients and the availability of organs from deceased donors. The last few years has seen a small, but increasing contribution from altruistic (or good Samaritan or nondirected) donors. However, use of organs from such donors is associated with ethical as well as practical issues. The rights of the well-informed and consented donor to donate must be balanced against the rights of the surgeons to decline to offer such a service. PMID:21981747
Full Text Available Indian defence aeronautical industry, while becoming a global business, demands a largeeffort to monitor quality management system (QMS and to ensure quality of aeronauticalproducts. An effort is being made to look for an effective QMS for aeronautical industry in India,which will also meet the requirements of the regulatory authority.The essential features of an effective QMS are described and compared with the presentlyavailable QMS standards for defence aeronautical industry such as QCSR: 2002 (DGAQA, India,Def Stan (MOD, UK, ISO, AQAPs (NATO and Society of Automotive Engineers (SAE aerospacestandards (AS. Evolution, relevance and review of the existing standards, to meet the requirementsof the industry as well as regulatory authority, have been made to bring out the special featuresand differences. The study leads to the most acceptable standard of SAE-AS-9100 (Rev B.With suitable modifications to include regulatory requirement of assistance for governmentquality assurance in the standard, when complied with, it will fully meet the QMS requirementsof the Indian defence aeronautical supply organisations as well as the requirements of theregulatory authority. Minor reorientation of the regulatory functions and inclusion of the QMSin the defence aeronautical supply orders are also suggested.
Pieterse, C.M.J.; Loon, L.C. van
Salicylic acid is an important signalling molecule involved in both locally and systemically induced disease resistance responses. Recent advances in our understanding of plant defence signalling have revealed that plants employ a network of signal transduction pathways, some of which are independen
The man-in-the-middle defence is all about rehabilitating Charlie. For 20 years we’ve worried about this guy in the middle, Charlie, who’s forever intercalating himself into the communications between Alice and Bob, and people have been very judgemental about poor Charlie, saying that Charlie is a wicked person. Well, we’re not entirely convinced.
Full Text Available Suicidal behaviour is a challenge for military forces around the world. Suicide can be a reaction in peacekeeping operations or conventional warfare, because the stressful nature of both types of operations can force military members to such a catastrophic end. This article focuses on the necessary knowledge and skills for a better understanding of suicidal behaviour in the South African National Defence Force (SANDF for members on different levels. It discusses the operational environment, with specific reference to peacekeeping operations or conventional warfare as contributing factors, risk factors, and the prevention and proper management of suicide by means of educating commanders and members of the multi-professional team (MPT.
Since the ending of the Cold War, the defence sector, particularly the areas of military logistics and defence acquisition, has been undergoing a comprehensive transformation. There are several factors that explain this transformation: changes in defence and security policies for nations and organisations; reductions in defence expenditure; participation in Peace Support Operations; Lessons Learned from these operations, especially in the area of logistics; revolutionary development in the ar...
人的自利行为是主流经济学分析的核心命题,随着经济活动实践的发展和理论研究的不断深入,经济学理论对人行为的研究已经从完全的自利行为走向利他行为。利他行为的内在机制可以通过利用亲缘、基因、群体选择、文化遗传、互惠及自人激励得到解释。%Human＇s self-serving behavior is the core propositions in the mainstream economic analysis.With the development of economic practice and the deepening of theoretical study,the research on human behavior in economic theory has gone from completely self-serving behavior to altruistic behavior.The internal mechanism of altruistic behavior can be explained with the genetic intrinsic mechanism,gene,group selection,cultural heritage,mutual and self-motivation.
Ishida, Yuko; Kuwahara, Yasumasa; Dadashipour, Mohammad; Ina, Atsutoshi; Yamaguchi, Takuya; Morita, Masashi; Ichiki, Yayoi; Asano, Yasuhisa
Soldiers of some eusocial insects exhibit an altruistic self-destructive defense behavior in emergency situations when attacked by large enemies. The swarm-forming invasive millipede, Chamberlinius hualienensis, which is not classified as eusocial animal, exudes irritant chemicals such as benzoyl cyanide as a defensive secretion. Although it has been thought that this defensive chemical was converted from mandelonitrile, identification of the biocatalyst has remained unidentified for 40 years. Here, we identify the novel blood enzyme, mandelonitrile oxidase (ChuaMOX), which stoichiometrically catalyzes oxygen consumption and synthesis of benzoyl cyanide and hydrogen peroxide from mandelonitrile. Interestingly the enzymatic activity is suppressed at a blood pH of 7, and the enzyme is segregated by membranes of defensive sacs from mandelonitrile which has a pH of 4.6, the optimum pH for ChuaMOX activity. In addition, strong body muscle contractions are necessary for de novo synthesis of benzoyl cyanide. We propose that, to protect its swarm, the sacrificial millipede also applies a self-destructive defense strategy-the endogenous rupturing of the defensive sacs to mix ChuaMOX and mandelonitrile at an optimum pH. Further study of defensive systems in primitive arthropods will pave the way to elucidate the evolution of altruistic defenses in the animal kingdom. PMID:27265180
Full Text Available Other cell interference (OCI degrades the achievable capacity of downlink multiuser multiple-input multiple-output (MU-MIMO systems seriously. Among OCI mitigation schemes, methods that sacrifice ξ degrees of freedom to nullify the OCI have been proven to be helpful to improve the cell edge throughput. However, since interference nulling schemes can only improve the signal to interference plus noise ratio (SINR of ξ users, they are not optimal in terms of average cell throughput, especially for low to medium OCI levels. We explore the question whether it is better to improve the SINR of every user in other cells rather than benefit ξ users. An altruistic precoding method to minimize the sum of generated interference for all of the other cell users is proposed with ξ degrees of freedom being sacrificed. With the altruistic precoding method, we deduce the lower bound on the capacity and solve the multicell user selection problem with a local optimal solution in which only eigenvalues of interfering channels are needed to be shared. Simulation results demonstrate that the proposed method outperforms the existing algorithms at any OCI level. Furthermore, we also analyze the best choice of degrees of freedom used to mitigate OCI through simulation.
Dirk J. Geldenhuys
Full Text Available Orientation: This article deals with the unconscious role of risk management in an African country.Research purpose: The aim of the study is to describe how risk management unconsciously influences behaviour when doing business in an African country.Motivation for the study: Operational risk management is a rational management imperative. However, this does not take cognisance of the unconscious role of risk management. A systems-psychodynamic perspective might be particularly relevant if the anxiety implied in risk management is not appropriately contained. Awareness of these dynamics may provide an opportunity for addressing them and allow for a more holistic way of managing risk.Research design, approach and method: The researchers conducted the study as a qualitative case study in an African country. They used purposive sampling and analysed the data using qualitative content analysis.Main findings: Viewing risk management from a systems-psychodynamic perspective allowed the researchers to identify the influence of risk management on the behaviour of people. The emerging hypothesis was that, if businesses do not address the anxiety underlying risk management, managing risk becomes a social defence against the anxiety.Practical/managerial implications: Awareness of the anxiety involved in risk management may assist businesses to manage risk in a more realistic way, making provision for, and even capitalising on, the human element.Contributions/value-add: The article provides a systems-psychodynamic, and hence a more complete, perspective of operational risk management when doing business in an African country.
Rupia, Emmanuel J; Binning, Sandra A; Roche, Dominique G; Lu, Weiqun
Survival depends on appropriate behavioural and physiological responses to danger. In addition to active 'fight-flight' defence responses, a passive 'freeze-hide' response is adaptive in some contexts. However, the physiological mechanisms determining which individuals choose a given defence response remain poorly understood. We examined the relationships among personality, metabolic performance and physiological stress responses across an environmental gradient in the olive flounder, Paralichthys olivaceus. We employed four behavioural assays to document the existence of two distinct behavioural types ('bold' and 'shy') in this species. We found consistent metabolic differences between individuals of a given behavioural type across an environmental gradient: shy individuals had overall lower aerobic scope, maximum metabolic rate and standard metabolic rate than bold individuals in both high (25 ppt) and low (3 ppt) salinity. These behavioural and metabolic differences translated into divergent physiological responses during acute stress: shy individuals adopted a passive 'freeze-hide' response by reducing their oxygen consumption rates (akin to shallow breathing) whereas bold individuals adopted an active 'fight-flight' response by increasing their rates of respiration. These distinct defence strategies were repeatable within individuals between salinity treatments. Although it has been suggested theoretically, this is the first empirical evidence that the metabolic response to stressful situations differs between bold and shy individuals. Our results emphasize the importance of incorporating physiological measures to understand the mechanisms driving persistent inter-individual differences in animals. PMID:27044558
-making capacities and capabilities. For many years, a genuine European defence policy remained a distant dream for an exclusive group of political leaders from federally oriented states such as Belgium and Luxembourg. Yet since 1999, the EU has carried out 23 military missions in the Balkans, Africa and Asia. The...... Union is thus gradually emerging as an important player on the international scene, with a strategic vision, as well as diplomatic, civilian and military crisis-management instruments that complement the existing economic, commercial, humanitarian and development policies on which the EU has hitherto...... built its reputation as a ‘soft power'. Despite its rapid development, many still regard the EU as weak and ineffi cient when it comes to security and defence policy. Moreover, the EU struggles with internal divisions and has a strained relationship with NATO. Nonetheless, there are good reasons to...
Rautio, Pasi; Kesti, Kari; Bergvall, Ulrika A.; Tuomi, Juha; Leimar, Olof
Large herbivores select food at several spatial scales: plant communities are chosen at a landscape scale, plant patches are chosen within a plant community, and individual plants within a patch. Foraging decision at the patch level can result in associational effects in plant communities and populations. Several studies have shown that herbivore attack and consumption rates may not only depend on a plant's own defence traits, but also on the defence traits of its neighbours. In the present experiment we investigated whether the spatial scale of the food distribution affects food selection by fallow deer and whether the foraging behaviour gives rise to associational effects in plant defences. In a population of captured wild fallow deer we simulated a natural situation where two separate plant patches are exposed to intense herbivory pressure. We presented different spatial arrangements of low- and high-tannin food to the deer, varying the frequency of the feeder types within and between patches. We found that the deer consumed palatable food among the unpalatable food on average as much as they consumed palatable food among other palatable feeders. However, when unpalatable food occurred among the palatable food it was more consumed than among other unpalatable feeders. Hence, we did not find support for associational defence, but our results supported associational susceptibility. At the between patch level a patch of mainly high-tannin feeders was consumed less when presented near to a patch of mainly low-tannin feeders, suggesting that for well-defended plants having palatable neighbours in a nearby patch might accentuate the effectiveness of their defence.
de Groot, Judith. I. M.; Steg, Linda; Keizer, Martijn; Farsang, Andrea; Watt, Alan
In this article the authors examine whether the significance of biospheric values as a separate cluster next to egoistic and altruistic values is mainly a Western European phenomenon or whether biospheric values are also endorsed as a value in its own right in post-socialist Hungary. In two differen
Edele, Aileen; Dziobek, Isabel; Keller, Monika
Experimental games like the dictator game have proven of great value for the study of altruism and sharing behavior. It has been shown that individuals differ substantially in the amount of money they offer to an anonymous receiver. Yet, to date little is known about how personality dispositions shape differences in altruistic sharing. The current…
Atopic dermatitis (AD) is an inflammatory skin disease, typically with a chronic relapsing course and a defective skin barrier function. Recently, mutations of the skin barrier gene encoding filaggrin have been reported in a portion of the patients. In this thesis some aspects of defence defects in AD were studied. In paper I, the risk of developing any cancer was increased by 13%. Excess risks were observed for cancers of the esophagus, pancreas, brain, and lung and for...
Sumati Sharma; Anil Kumar Singh; Vijay Lakshmi Kakkar
Basic elements of collection development process are presented in this paper. Collection development of Defence Science Library is discussed in detail. Data presented in the paper reflects that there is a steep fall in the number of titles subscribed during last six years. On the other hand reference collection of library has become richer during past few years. Resource sharing is discussed as a solution to overcome the problem of increased cost of publications and present financial crunch.h...
Sumati Sharma; Anil Kumar Singh; Vijay Lakshmi Kakkar
Basic elements of collection development process are presented in this paper. Collection development of Defence Science Library is discussed in detail. Data presented in the paper reflects that there is a steep fall in the number of titles subscribed during last six years. On the other hand reference collection of library has become richer during past few years. Resource sharing is discussed as a solution to overcome the problem of increased cost of publications and present financial crunch.
Vallet-Gely, Isabelle; Lemaitre, Bruno; Boccard, Frédéric
Recent genetic and molecular analyses have revealed how several strategies enable bacteria to persist and overcome insect immune defences. Genetic and genomic tools that can be used with Drosophila melanogaster have enabled the characterization of the pathways that are used by insects to detect bacterial invaders and combat infection. Conservation of bacterial virulence factors and insect immune repertoires indicates that there are common strategies of host invasion and pathogen eradication. ...
Anderson, Ross; Bond, Mike
Eliminating middlemen from security protocols helps less than one would think. EMV electronic payments, for example, can be made fairer by adding an electronic attorney - a middleman which mediates access to a customer’s card. We compare middlemen in crypto protocols and APIs with those in the real world, and show that a man-in-the-middle defence is helpful in many circumstances. We suggest that the middleman has been unfairly demonised.
Sharma, O. P.; Sharma, K. D.
A study of mycoflora on footwears and defence articles from Agra city was made. In all 38 fungi belonging to different genera were recorded. Out of these, 17 fungal species were isolated for the first on these articles. A new variety i.e., Aspergillus sydowii var. agraii Sharma and Sharma was also created. Species of Aspergillus, Penicillium, Paecilomyces, Drechslera, Alternaria, Fusarium and Trichoderma were found to be dominant in all the cases. Maximum species were recorded from gents foot...
This conference involves subjects of radiation protection, programming of civil defence, on the implementation of 1990 ICRP recommendation, thermoluminescence properties of bone equivalent calcium phosphate ceramics, potassium body burdens in occupational users of egyptian nuclear research centre, transport of radionuclides in fresh water stream, water treatment process for nuclear reactor, research activities related to internal contamination and bioassay and experience and environmental radiation monitoring in inshass. it contains of figures and tables
Cuevas, Ruben; Cuevas, Angel; Kaune, Sebastian; Guerrero, Carmen; Rejaie, Reza
BitTorrent is the most popular P2P content delivery application where individual users share various type of content with tens of thousands of other users. The growing popularity of BitTorrent is primarily due to the availability of valuable content without any cost for the consumers. However, apart from required resources, publishing (sharing) valuable (and often copyrighted) content has serious legal implications for user who publish the material (or publishers). This raises a question that whether (at least major) content publishers behave in an altruistic fashion or have other incentives such as financial. In this study, we identify the content publishers of more than 55k torrents in 2 major BitTorrent portals and examine their behavior. We demonstrate that a small fraction of publishers are responsible for 66% of published content and 75% of the downloads. Our investigations reveal that these major publishers respond to two different profiles. On one hand, antipiracy agencies and malicious publishers pub...
Althoff, Tim; Jurafsky, Dan
Requests are at the core of many social media systems such as question & answer sites and online philanthropy communities. While the success of such requests is critical to the success of the community, the factors that lead community members to satisfy a request are largely unknown. Success of a request depends on factors like who is asking, how they are asking, when are they asking, and most critically what is being requested, ranging from small favors to substantial monetary donations. We present a case study of altruistic requests in an online community where all requests ask for the very same contribution and do not offer anything tangible in return, allowing us to disentangle what is requested from textual and social factors. Drawing from social psychology literature, we extract high-level social features from text that operationalize social relations between recipient and donor and demonstrate that these extracted relations are predictive of success. More specifically, we find that clearly communic...
Pollier, J.; Moses, T.; González-Guzmán, M.; Geyter, N. De; Lippens, S; Bossche, R.V.; Marhavý, P.; Kremer, A; Morreel, K.; Guérin, C J; Tava, A.; Oleszek, W; J. M. Thevelein; Campos Martínez, Narciso; Goormachtig, S.
Jasmonates are ubiquitous oxylipin-derived phytohormones that are essential in the regulation of many development, growth and defence processes. Across the plant kingdom, jasmonates act as elicitors of the production of bioactive secondarymetabolites that serve in defence against attackers. Knowledge of the conserved jasmonate perception and early signalling machineries is increasing, but the downstream mechanisms that regulate defence metabolism remain largely unknown. Herewe showthat, in th...
Kolar, Satya S.; McDermott, Alison M.
The eye and its associated tissues including the lacrimal system and lids have evolved several defence mechanisms to prevent microbial invasion. Included among this armory are several host-defence peptides. These multifunctional molecules are being studied not only for their endogenous antimicrobial properties but also for their potential therapeutic effects. Here the current knowledge of host-defence peptide expression in the eye will be summarized. The role of these peptides in eye disease ...
Masys, Anthony J
Networks and Network Analysis for Defence and Security discusses relevant theoretical frameworks and applications of network analysis in support of the defence and security domains. This book details real world applications of network analysis to support defence and security. Shocks to regional, national and global systems stemming from natural hazards, acts of armed violence, terrorism and serious and organized crime have significant defence and security implications. Today, nations face an uncertain and complex security landscape in which threats impact/target the physical, social, economic
Smith, Karen E.
Alongside France, the UK is generally viewed as one of the most important actors in EU defence policy. Karen E. Smith assesses what impact the UK leaving the EU might have in the area of defence. She writes that a Brexit would not spell the end for common European defence as a whole, particularly given the UK’s gradual withdrawal from its leadership role on foreign security and defence matters. However she argues that it would nevertheless deprive the EU of a potential key player, while also ...
1.Research Production Association 'LUCH' (RPA 'LUCH') have worked at atomic industry for 51 years. Now it is one of the leading scientific production centers of Russia Ministry of Atomic Energy. Not long ago it was a complex of Scientific Research Institute, experimental plant and Obyedenennaya Expedicia at the Semipalatinsk test site (now it is the Institute of Atomic Energy NNC RK). Basic directions of the complex activity are defence tasks. These tasks are to develop structure and technology of producing fuel assemblies for NRE (nuclear rocket engine) reactors. Also the tasks include testing the fuel assemblies at IWG-1, RWD and RA reactors. Also the tasks include structure and technology development, production and testing electric generating channels for nuclear thermal emission converters of nuclear energy into electric one (space board power engineering), power metal optics for powerful lasers, high temperature gas reactors. 2.Main directions of RPA 'LUCH' conversion were determined on the basis of possibilities for developing main achievements in defence technology directions.These directions are high temperature materials and constructions (carbides, refractory metals, measurements, optics, uranium compound, beryllium, molybdenum) 3.At present at RPA 'LUCH' there have been created experimental and industrial productions making temperature sensors for Atomic Electric Power Stations (AEPS). Also these manufactures release commercial products. They produce technological equipment of carbide-silicon for electronic industry as well as parts or X-ray tubes, vermiculite parts for cable driving of AEP stations (high temperature, fireproof ones) of thermal and electrical accumulators. Thus, a scientific-production center is being created. Core of it is a scientific engineers group and development directions, generated from orders of defence department, as well as new foreign technologies (along with investments).The example of the said above can be development of a
After having shown that nuclear deterrence has been efficient since 1945 (nuclear weapons prevented from war, nuclear deterrence contributed to the reduction of risks related to proliferation), the author discusses the amorality and illegality of nuclear deterrence (its ethics can indeed be a matter of discussion, as well as issues like self-defence and international humanitarian law). On another hand, he shows that deterrence costs remain acceptable and that substitutes to nuclear deterrence are not credible. He concludes that deterrence is therefore still useful and legitimate
Vallet-Gely, Isabelle; Lemaitre, Bruno; Boccard, Frédéric
Recent genetic and molecular analyses have revealed how several strategies enable bacteria to persist and overcome insect immune defences. Genetic and genomic tools that can be used with Drosophila melanogaster have enabled the characterization of the pathways that are used by insects to detect bacterial invaders and combat infection. Conservation of bacterial virulence factors and insect immune repertoires indicates that there are common strategies of host invasion and pathogen eradication. Long-term interactions of bacteria with insects might ensure efficient dissemination of pathogens to other hosts, including humans. PMID:18327270
Castellacci, Fulvio; Blom, Martin; Fevolden, Arne Martin
The paper investigates the trade-off between innovation and defence industrial policy. It presents an agent-based simulation model calibrated for the Norwegian defence industry that compares different policy scenarios and examines the effects of a pending EU market liberalization process. The paper points to two main results. (1) It finds that a pure scenario where national authorities focus on, and provide support exclusively for, either a) international competitiveness or b) national defenc...
Camilla L. Krog; Krishna Govender
Orientation: Understanding the relationship between a project sponsor’s servant leadership traits and employee commitment, trust and innovative behaviour.Research purpose: This study aimed to understand the relationship, if any, between a project sponsor’s servant leadership traits of altruistic calling, emotional healing, wisdom, persuasive mapping and organisational stewardship and a project team’s empowerment, commitment, trust and innovative behaviour.Motivation of the study: Most project...
In Finland, the local authorities and the central government are responsible for the general planning of civil defence and for joint protection measures, while individual citizens and corporations are responsible for individual protection measures. In practice, housing companies and employers are required to carry out the statutory preparations needed for civil defence. Preparation for accidents can be improved, for instance, by awareness of correct actions in each situation. The most important individual protection measures are first aid, basic fire extinguishing skills, provision of shelter, and acquisition of a reserve stock of provisions at home. A reserve stock means that there is a sufficient supply of non-perishable foodstuffs, medication and water vessels for a couple of days' needs at home. A warning of imminent danger is usually given by sounding a general alarm signal. Even slight changes in radiation are reported immediately. Shelter should primarily be sought indoors. Instructions may be given on the radio, on TV and by means of loudspeakers. If there is a radiation risk, the thyroid may be protected against radioactive iodine by taking iodine tablets, but they should not be taken until so instructed by the authorities. (2 figs.)
Gorzelak, Monika A.; Asay, Amanda K.; Pickles, Brian J.; Simard, Suzanne W
Adaptive behaviour of plants, including rapid changes in physiology, gene regulation and defence response, can be altered when linked to neighbouring plants by a mycorrhizal network (MN). Mechanisms underlying the behavioural changes include mycorrhizal fungal colonization by the MN or interplant communication via transfer of nutrients, defence signals or allelochemicals. We focus this review on our new findings in ectomycorrhizal ecosystems, and also review recent advances in arbuscular myco...
A peculiar irony characterizes the perception of global terrorism—in the strong penchant to flavor it with ethno or religious centric biases or in the disavowal of any auxiliary circumstance leading up to the sporadic incidence of violence. This paper analyzes the Mumbai attacks of November 26th, 2009 from the context of altruistic suicide/homicide. The waging of war against anonymous targets in Mumbai was by all means impersonal. It could be connected to an aftermath of several factors: Kash...
In the current climate of budgetary restrictions, it is fair to question the weight of military nuclear defence spending. Upon examination, however, nuclear deterrence has numerous military, industrial, and technological benefits. It is, in fact, totally intertwined with the other elements of our defence system. (author)
N. S. Venkatesan
Full Text Available Defence science in India owes its origin and early growth to Professor DS Kothari. From humble beginnings the Defence Research and Development Organization (DRDO has grown into a major national scientific agency over the last four and a half decades.
Knudsen, Nikolas Sten; Andersen, Thomas Bull
The purpose of the present study was to create a methodology which can provide information about gaps in an opposing team’s defence. To illustrate the methodology, a defence was tracked during a game in the danish Superliga using ZXY radio tracking and analysed using the methodology. Results show...
Kluth, Michael Friederich
raises the question: are we witnessing an incursion of spillover mechanisms into the ‘High Politics' domain of the defence industry? What are the drivers eroding the ‘High Politics' character of defence industry integration? Are market forces at play? Does it reflect pressures for institutional......Defence industry regulation falls in between the ‘Low Politics' of ensuring market efficiency and the ‘High Politics' of preserving the national defence industrial and technological base. It has been exempt from internal market regulation and integrative initiatives have been managed on an...... intergovernmental base. In the past 10 years, however, the defence industries of the major EU powers have instigated a move from cross national collaboration to cross national consolidation. Cross border mergers and acquisitions has been carried out and pressures for regulatory mainstreaming is mounting. This...
Bouarab, K.; Melton, R.; Peart, J.; Baulcombe, D.; Osbourn, A.
Plant disease resistance can be conferred by constitutive features such as structural barriers or preformed antimicrobial secondary metabolites. Additional defence mechanisms are activated in response to pathogen attack and include localized cell death (the hypersensitive response). Pathogens use different strategies to counter constitutive and induced plant defences, including degradation of preformed antimicrobial compounds and the production of molecules that suppress induced plant defences. Here we present evidence for a two-component process in which a fungal pathogen subverts the preformed antimicrobial compounds of its host and uses them to interfere with induced defence responses. Antimicrobial saponins are first hydrolysed by a fungal saponin-detoxifying enzyme. The degradation product of this hydrolysis then suppresses induced defence responses by interfering with fundamental signal transduction processes leading to disease resistance.
Urban, Mark C; Bürger, Reinhard; Bolnick, Daniel I
Evolutionary biologists typically predict future evolutionary responses to natural selection by analysing evolution on an adaptive landscape. Much theory assumes symmetric fitness surfaces even though many stabilizing selection gradients deviate from symmetry. Here we revisit Lande's adaptive landscape and introduce novel analytical theory that includes asymmetric selection. Asymmetric selection and the resulting skewed trait distributions bias equilibrium mean phenotypes away from fitness peaks, usually toward the flatter shoulder of the individual fitness surface. We apply this theory to explain a longstanding paradox in biology and medicine: the evolution of excessive defences against enemies. These so-called extraordinary defences can evolve in response to asymmetrical selection when marginal risks of insufficient defence exceed marginal costs of excessive defence. Eco-evolutionary feedbacks between population abundances and asymmetric selection further exaggerate these defences. Recognizing the effect of asymmetrical selection on evolutionary trajectories will improve the accuracy of predictions and suggest novel explanations for apparent sub-optimality. PMID:23820378
As antimissile defence has become a mean to compensate the limitations of nuclear deterrence in Asia, notably within the frame of the US-North Korea relationship, but has also influence on the relationships between countries which do not possess an actual operational antimissile defence like Pakistan and India, the author proposes an assessment of the consequences antimissile defence may have on deterrence logics in Asia. He also notices that various issues must be taken into account: arsenal sizes, the slow rate of ballistic modernisation processes, the weaknesses of C4ISR systems and advanced alarm systems. He recalls the peculiarities of antimissile defence, and then addresses the cases of North Korea, India and Pakistan, and China. For each country, he analyses and discusses the influence of a choice or of the existence of an antimissile defence on the nuclear strategy and doctrine, but also on the posture of other countries like the USA
Full Text Available We identify and explain the mechanisms that account for the emergence of fairness preferences and altruistic punishment in voluntary contribution mechanisms by combining an evolutionary perspective together with an expected utility model. We aim at filling a gap between the literature on the theory of evolution applied to cooperation and punishment, and the empirical findings from experimental economics. The approach is motivated by previous findings on other-regarding behavior, the co-evolution of culture, genes and social norms, as well as bounded rationality. Our first result reveals the emergence of two distinct evolutionary regimes that force agents to converge either to a defection state or to a state of coordination, depending on the predominant set of self- or other-regarding preferences. Our second result indicates that subjects in laboratory experiments of public goods games with punishment coordinate and punish defectors as a result of an aversion against disadvantageous inequitable outcomes. Our third finding identifies disadvantageous inequity aversion as evolutionary dominant and stable in a heterogeneous population of agents endowed initially only with purely self-regarding preferences. We validate our model using previously obtained results from three independently conducted experiments of public goods games with punishment.
Hetzer, Moritz; Sornette, Didier
We identify and explain the mechanisms that account for the emergence of fairness preferences and altruistic punishment in voluntary contribution mechanisms by combining an evolutionary perspective together with an expected utility model. We aim at filling a gap between the literature on the theory of evolution applied to cooperation and punishment, and the empirical findings from experimental economics. The approach is motivated by previous findings on other-regarding behavior, the co-evolution of culture, genes and social norms, as well as bounded rationality. Our first result reveals the emergence of two distinct evolutionary regimes that force agents to converge either to a defection state or to a state of coordination, depending on the predominant set of self- or other-regarding preferences. Our second result indicates that subjects in laboratory experiments of public goods games with punishment coordinate and punish defectors as a result of an aversion against disadvantageous inequitable outcomes. Our third finding identifies disadvantageous inequity aversion as evolutionary dominant and stable in a heterogeneous population of agents endowed initially only with purely self-regarding preferences. We validate our model using previously obtained results from three independently conducted experiments of public goods games with punishment. PMID:24260101
San Martín, René; Kwak, Youngbin; Pearson, John M; Woldorff, Marty G; Huettel, Scott A
Human altruism is often expressed through charitable donation-supporting a cause that benefits others in society, at cost to oneself. The underlying mechanisms of this other-regarding behavior remain imperfectly understood. By recording event-related-potential (ERP) measures of brain activity from human participants during a social gambling task, we identified markers of differential responses to receipt of monetary outcomes for oneself vs for a charitable cause. We focused our ERP analyses on the frontocentral feedback-related negativity (FRN) and three subcomponents of the attention-related P300 (P3) brain wave: the frontocentral P2 and P3a and the parietal P3b. The FRN distinguished between gains and losses for both self and charity outcomes. Importantly, this effect of outcome valence was greater for self than charity for both groups and was independent of two altruism-related measures: participants' pre-declared intended donations and the actual donations resulting from their choices. In contrast, differences in P3 subcomponents for outcomes for self vs charity strongly predicted both of our laboratory measures of altruism-as well as self-reported engagement in real-life altruistic behaviors. These results indicate that individual differences in altruism are linked to individual differences in the relative deployment of attention (as indexed by the P3) toward outcomes affecting other people. PMID:27030510
Petrican, Raluca; Todorov, Alexander; Burris, Christopher T.; Rosenbaum, R. Shayna; Grady, Cheryl
A trustworthy appearance is regarded as a marker of a globally positive personality and, thus, evokes a host of benevolent responses from perceivers. Nevertheless, it is yet to be determined whether the reverse is also true, that is, whether social targets who evoke unambiguously benign motivations in perceivers are regarded as possessing a more trustworthy appearance (cf. Oosterhof & Todorov, 2008). To this end, elderly long-term married couples completed measures of partner-directed altruistic motivation, accommodative behaviors, marital satisfaction, and trust in the partner. They also completed a face-processing task involving spousal and stranger faces one year later. Higher motivation to prioritize a spouse’s well-being (but none of the other relationship functioning variables assessed) predicted perceiving one’s spouse’s emotionally neutral face as being more trustworthy-looking. Results are discussed in the context of the reciprocal relationship between higher-order motivational processes and basic perceptual mechanisms in shaping relational climates. PMID:27330235
Liu, Pei-Pei; Safin, Vasiliy; Yang, Barry; Luhmann, Christian C
Prior research has suggested that recipients of generosity behave more generously themselves (a direct social influence). In contrast, there is conflicting evidence about the existence of indirect influence (i.e., whether interacting with a recipient of generosity causes one to behave more generously), casting doubt on the possibility that altruistic behavior can cascade through social networks. The current study investigated how far selfish and generous behavior can be transmitted through social networks and the cognitive mechanisms that underlie such transmission. Participants played a sequence of public goods games comprising a chain network. This network is advantageous because it permits only a single, unambiguous path of influence. Furthermore, we experimentally manipulated the behavior of the first link in the chain to be either generous or selfish. Results revealed the presence of direct social influence, but no evidence for indirect influence. Results also showed that selfish behavior exerted a substantially greater influence than generous behavior. Finally, expectations about future partners' behavior strongly mediated the observed social influence, suggesting an adaptive basis for such influence. PMID:26469066
Computer Security Team
It is an unfair imbalance: the (computer) security of a system/service is only as strong as the weakest link in the chain of protection. This provides attackers with an incredible advantage: they can choose when to attack, where and with which means. The defence side is permanently under pressure: they must defend at all times all assets against all eventualities. For computer security, this means that every computer system, every account, every web site and every service must be properly protected --- always. In particular, at CERN, those services visible to the Internet are permanently probed. Web sites and servers are permanently scanned by adversaries for vulnerabilities; attackers repeatedly try to guess user passwords on our remote access gateways like LXPLUS or CERNTS; computing services, e.g. for Grid computing, are analysed again and again by malicious attackers for weaknesses which can be exploited. Thanks to the vigilance of the corresponding system and service experts, these atta...
O. P. Sharma
Full Text Available A study of mycoflora on footwears and defence articles from Agra city was made. In all 38 fungi belonging to different genera were recorded. Out of these, 17 fungal species were isolated for the first on these articles. A new variety i.e., Aspergillus sydowii var. agraii Sharma and Sharma was also created. Species of Aspergillus, Penicillium, Paecilomyces, Drechslera, Alternaria, Fusarium and Trichoderma were found to be dominant in all the cases. Maximum species were recorded from gents footwear and books ankle in comparison to ladies footwear. All these fungi were grouped as (i active (15 isolates, (iimoderate (15 isolates and (iii slow leather deteriogens (8 isolates on the basis of screening.
Romania has been involved in the field of security and defense, named until December 2009 ESDP (European Security and Defence Policy) and is now subject to the CSDP, even before joining the EU, recorded at the 1st of January 2007. Today, Romania is an active participant in CSDP, both political dimension, dedicated to support interests identified by Member States as common security and defense, as well as the operational, contributing in a large number of EU crisis management .
Bortoleto, Ana Paula, E-mail: email@example.com [Department of Urban Engineering, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Kurisu, Kiyo H.; Hanaki, Keisuke [Department of Urban Engineering, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan)
Highlights: Black-Right-Pointing-Pointer We model waste prevention behaviour using structure equation modelling. Black-Right-Pointing-Pointer We merge attitude-behaviour theories with wider models from environmental psychology. Black-Right-Pointing-Pointer Personal norms and perceived behaviour control are the main behaviour predictors. Black-Right-Pointing-Pointer Environmental concern, moral obligation and inconvenience are the main influence on the behaviour. Black-Right-Pointing-Pointer Waste prevention and recycling are different dimensions of waste management behaviour. - Abstract: Understanding waste prevention behaviour (WPB) could enable local governments and decision makers to design more-effective policies for reducing the amount of waste that is generated. By merging well-known attitude-behaviour theories with elements from wider models from environmental psychology, an extensive cognitive framework that provides new and valuable insights is developed for understanding the involvement of individuals in waste prevention. The results confirm the usefulness of the theory of planned behaviour and of Schwartz's altruistic behaviour model as bases for modelling participation in waste prevention. A more elaborate integrated model of prevention was shown to be necessary for the complete analysis of attitudinal aspects associated with waste prevention. A postal survey of 158 respondents provided empirical support for eight of 12 hypotheses. The proposed structural equation indicates that personal norms and perceived behaviour control are the main predictors and that, unlike the case of recycling, subjective norms have a weak influence on WPB. It also suggests that, since social norms have not presented a direct influence, WPB is likely to be influenced by a concern for the environment and the community as well by perceptions of moral obligation and inconvenience. Results also proved that recycling and waste prevention represent different dimensions of waste
Highlights: ► We model waste prevention behaviour using structure equation modelling. ► We merge attitude–behaviour theories with wider models from environmental psychology. ► Personal norms and perceived behaviour control are the main behaviour predictors. ► Environmental concern, moral obligation and inconvenience are the main influence on the behaviour. ► Waste prevention and recycling are different dimensions of waste management behaviour. - Abstract: Understanding waste prevention behaviour (WPB) could enable local governments and decision makers to design more-effective policies for reducing the amount of waste that is generated. By merging well-known attitude–behaviour theories with elements from wider models from environmental psychology, an extensive cognitive framework that provides new and valuable insights is developed for understanding the involvement of individuals in waste prevention. The results confirm the usefulness of the theory of planned behaviour and of Schwartz’s altruistic behaviour model as bases for modelling participation in waste prevention. A more elaborate integrated model of prevention was shown to be necessary for the complete analysis of attitudinal aspects associated with waste prevention. A postal survey of 158 respondents provided empirical support for eight of 12 hypotheses. The proposed structural equation indicates that personal norms and perceived behaviour control are the main predictors and that, unlike the case of recycling, subjective norms have a weak influence on WPB. It also suggests that, since social norms have not presented a direct influence, WPB is likely to be influenced by a concern for the environment and the community as well by perceptions of moral obligation and inconvenience. Results also proved that recycling and waste prevention represent different dimensions of waste management behaviour requiring particular approaches to increase individuals’ engagement in future policies.
Full Text Available Grazing-induced plant defences that reduce palatability to herbivores are widespread in terrestrial plants and seaweeds, but they have not yet been reported in seagrasses. We investigated the ability of two seagrass species to induce defences in response to direct grazing by three associated mesograzers. Specifically, we conducted feeding-assayed induction experiments to examine how mesograzer-specific grazing impact affects seagrass induction of defences within the context of the optimal defence theory. We found that the amphipod Gammarus insensibilis and the isopod Idotea chelipes exerted a low-intensity grazing on older blades of the seagrass Cymodocea nodosa, which reflects a weak grazing impact that may explain the lack of inducible defences. The isopod Synischia hectica exerted the strongest grazing impact on C. nodosa via high-intensity feeding on young blades with a higher fitness value. This isopod grazing induced defences in C. nodosa as indicated by a consistently lower consumption of blades previously grazed for 5, 12 and 16 days. The lower consumption was maintained when offered tissues with no plant structure (agar-reconstituted food, but showing a reduced size of the previous grazing effect. This indicates that structural traits act in combination with chemical traits to reduce seagrass palatability to the isopod. Increase in total phenolics but not in C:N ratio and total nitrogen of grazed C. nodosa suggests chemical defences rather than a modified nutritional quality as primarily induced chemical traits. We detected no induction of defences in Zostera noltei, which showed the ability to replace moderate losses of young biomass to mesograzers via compensatory growth. Our study provides the first experimental evidence of induction of defences against meso-herbivory that reduce further consumption in seagrasses. It also emphasizes the relevance of grazer identity in determining the level of grazing impact triggering resistance and
), don't pollute the industry environ and surroundings, don't do real danger of reirradiation and pollution but demand investigation of their origin; accidents as a result when personal and persons from population have gotten a doze of outward irradiation (over PN); accidents as a result when industry or surroundings have been polluted (over PN);.accidents, as a result of outward and inside irradiation of personal, persons from population (over NPP-norms of radiation safety). Volume and character of measures by foregoing radiation accidents and their consequence depend on groups and scale of accident. They include investigation of the accident reasons; realization the radiation control for estimation degree of ionizing radiation pressure to personal and individual persons from population; rendering medical help to victims; definition of surroundings pollution level; equipment, industrial and habitable places; prevention of further influence of ionizing radiation to population and spreading radionuclides in surroundings; elimination of disrepairs and liquidation of radiation accident source. Radiation accident in the nuclear engineering establishments and industry have been divided into accident and proper-crash. At present international organizations have divided a school of crashes and accidents at NPP. According to that scale 3 levels of accidents and 4 levels of crashes have been chosen. The accidents have been qualified: insignificant (1 level), middle difficulty (2 level), serious (3 level), but crashes - within the NPP (4 level), at the risk of surroundings (5 level), difficult (6 level), global (7 level). Character, volume and forms of measures by defence of population in the crashes at NPP depend on both the level of crash and the concrete radiation situation and stage of crash development. Those measures include: notification about crash; rendering medical help to victims, primary measures of personal and population defence (cover, iodine precautions
Full Text Available The main security problem that any state faces today is protecting itscitizens in countering organised crime and terrorism. Wars between states are lessfrequent than in previous eras. Border defence and border security are distinctmissions requiring different forces with different training and different equipment.Border defence is predominately against the armed forces of other states requiringtanks, aircraft and ships. Traditionally, border security includes the mission roles ofimmigration, crime, agriculture, finance, disease control and terrorism. Intelligencegathering and analysis using three methodologies - trends and patterns, frequency,and probability – provides a solution to the large and expensive armed forces forterritorial border defence and defines the ability to succeed in border security.
Amol A. Gokhale
Full Text Available Among cellular metals, aluminium foams are the most commonly produced, and provide a unique combination of properties such as: very low density, high energy absorption under static and dynamic compressions, blast amelioration, sound absorption, and flame resistance. Applications in automotive and defence sectors have been reported. Foams based on high melting point metals such as nickel and its alloys are also under active development throughout the world for applications requiring corrosion and oxidation resistance coupled with high temperature strength and relatively high thermal conductivity. Ceramic foams were developed elsewhere in the world primarily for biomedical applications, but are also suitable for defence applications for high temperature insulation. These cellular materials will provide new materials options to designers of aerospace, transport, and other defence systems.Defence Science Journal, 2011, 61(6, pp.567-575, DOI:http://dx.doi.org/10.14429/dsj.61.640
Sillitti, Alberto; Succi, Giancarlo; Messina, Angelo
This book presents high-quality original contributions on new software engineering models, approaches, methods, and tools and their evaluation in the context of defence and security applications. In addition, important business and economic aspects are discussed, with a particular focus on cost/benefit analysis, new business models, organizational evolution, and business intelligence systems. The contents are based on presentations delivered at SEDA 2015, the 4th International Conference in Software Engineering for Defence Applications, which was held in Rome, Italy, in May 2015. This conference series represents a targeted response to the growing need for research that reports and debates the practical implications of software engineering within the defence environment and also for software performance evaluation in real settings through controlled experiments as well as case and field studies. The book will appeal to all with an interest in modeling, managing, and implementing defence-related software devel...
Full Text Available The early development of textiles involved use of natural materials like cotton, wool and flax. The advent of the new technology revolutionized textiles which enables to develop synthetic fibers like lycra®, a segmented polyurethane-urea, which has exceptional elastic properties, Kevlar®, which has ultra high strength properties and is used as bulletproof vest. For the improvement of personal mobility, health care and rehabilitation, it requires to integrate novel sensing and actuating functions to textiles. Fundamental challenge in the development of smart textile is that drapability and manufacturability of smart textiles should not be affected. Textile fabrics embedded with sensors, piezoelectric materials, flame retardant materials, super hydrophobic materials, controlled drug release systems and temperature adaptable materials can play major role in the development of advanced and high-tech military clothes. Advancement in the textile materials has the capacity of improving comfort, mobility and protection in diverse hostile environment. In this study, the advancement in energy harvesting textiles, controlled release textiles and engineering textiles are presented.Defence Science Journal, 2013, 63(3, pp.331-339, DOI:http://dx.doi.org/10.14429/dsj.63.2756
Accident prevention is the first safety priority of both designers and operators. It is achieved through the use of reliable structures, components, systems and procedures in a plant operated by personnel who are committed to a strong safety culture. For future nuclear power plants, consideration of multiple failures and severe accidents will be achieved in a more systematic and complete way from the design stage. Defence in depth (DID) consists of a hierarchical deployment of different levels of equipment and procedures in order to maintain the effectiveness of physical barriers placed between radioactive materials and workers, the public or the environment, in normal operation, anticipated operational occurrences and, for some barriers, in accidents at the plant. The primary way of preventing accidents is to achieve a high quality in design, construction and operation of the plant, and thereby to ensure that deviations from normal operation are infrequent. The best way to meet these premises of effectiveness of the barriers and the Systems, Structures and Components (SSCs) is to develop an ageing management programme to prevent potential failures and accidents. In this work we will refer to the ageing management programme for Atucha I and Atucha II power plants and to the Atucha I spent fuel storage. (author)
Over the last few years, major focus of the nuclear debate has been turned towards the United States' proposal to erect a National Missile Defence (NMD) shield for itself. Of the existing nuclear weapon powers, China has been the most vociferous critic of this proposal. As and when this shield does become a reality, China will be the first to lose credibility as a deterrent against USA's existing nuclear arsenal. Therefore taking countermeasures against such a proposal is quite natural. China's approach towards non-proliferation mechanisms is steeped in realpolitik and its ability to manoeuvre them in its favour as a P5 and N5 power. Further, the Chinese leadership have been clear about the capabilities and limitations of nuclear weapons and treated them as diplomatic and political tools. The underlying aim is to preserve China's status as a dominant player in the international system while checkmating other possible challengers. Such a pragmatic approach is of far-reaching significance to all nations, especially those that possess nuclear weapons themselves. It will also be in India's long-term strategic interest to assess and take necessary corrective measures in its national security strategy, and make the composition of Indian nuclear strategy meet the desired goal. (author)
Ultraviolet (UV) radiation is usually divided into three wavelength ranges, which differ considerably from each other with respect to their effect on human health. UV-B radiation, in particular, weakens the body's resistance against cancer cells and thus increases cancer risk. Although virtually all UV-B radiation stops at the surface layer of skin, the whole body suffers from its adverse effects. UV radiation affects the body's defence mechanism relatively quickly. A reduction in the body's capacity to defend itself against alien substances can already be detected within a couple of days after the body has been exposed to a small amount of UV radiation. The risk of cancer increases slowly over the years. The skin cancers that are treated in hospitals today have their origin in the ways of life pursued in the 1960's and 70's. Factors affecting the amounts of UV doses received by Finns include trips to the South, solarium treatments and, to some extent, thinning of the ozone layer. (orig.) (4 figs.)
Tiwari, Aviral; Shahbaz, Muhammad
The aim of present is to reinvestigate the effect of defence spending on economic growth using Zivot and Andrews (1992) and Lee and Strazicich, (2003) structural unit root tests and ARDL bounds testing approach to cointegration in augmented version of Keynesian model for Indian economy. Our analysis confirmed long run relationship between the variables and, results indicated positive effect of defence spending on economic growth (also negative impact after a threshold point). Investment and t...
The white-collar crime attorney is a lawyer who is competent in general legal principles and in the substantive and procedural aspects of the law related to upper-class financial crime. Based on a sample of 310 convicted white-collar criminals and their defence lawyers, this paper presents results from statistical analysis of relationships between crime characteristics and defence characteristics to predict lawyer fame. Statistical regression analysis was applied to the sample, where amount o...
This article focuses on the members of Generation Y and their willingness to offer voluntary (unpaid) blood donations. Using statistics from various sources, a three-stage model is developed to explain blood donation behaviour especially of this generation. It consists of i) developing altruism, ii) raising the willingness to donate blood, and iii) activating actual blood donation behaviour. Members of Generation Y live in a Darwinistic society. They also to some degree act opportunistically,...
Kelly Rodney W
Full Text Available Abstract The human endometrium is an important site of innate immune defence, giving protection against uterine infection. Such protection is critical to successful implantation and pregnancy. Infection is a major cause of preterm birth and can also cause infertility and ectopic pregnancy. Natural anti-microbial peptides are key mediators of the innate immune system. These peptides, between them, have anti-bacterial, anti-fungal and anti-viral activity and are expressed at epithelial surfaces throughout the female genital tract. Two families of natural anti-microbials, the defensins and the whey acidic protein (WAP motif proteins, appear to be prominent in endometrium. The human endometrial epithelium expresses beta-defensins 1–4 and the WAP motif protein, secretory leukocyte protease inhibitor. Each beta-defensin has a different expression profile in relation to the stage of the menstrual cycle, providing potential protection throughout the cycle. Secretory leukocyte protease inhibitor is expressed during the secretory phase of the cycle and has a range of possible roles including anti-protease and anti-microbial activity as well as having effects on epithelial cell growth. The leukocyte populations in the endometrium are also a source of anti-microbial production. Neutrophils are a particularly rich source of alpha-defensins, lactoferrin, lysozyme and the WAP motif protein, elafin. The presence of neutrophils during menstruation will enhance anti-microbial protection at a time when the epithelial barrier is disrupted. Several other anti-microbials including the natural killer cell product, granulysin, are likely to have a role in endometrium. The sequential production of natural anti-microbial peptides by the endometrium throughout the menstrual cycle and at other sites in the female genital tract will offer protection from many pathogens, including those that are sexually transmitted.
de Aguiar, Lais Mattos; Figueira, Fernanda Hernandes; Gottschalk, Marco Silva; da Rosa, Carlos Eduardo
Glyphosate is a non-selective and post-emergent herbicide that affects plant growth. Animal exposure to this herbicide can lead to adverse effects, such as endocrine disruption, oxidative stress and behavioural disorders. Drosophilids have been utilized previously as an effective tool in toxicological tests. In the present study, the effects of a glyphosate-based herbicide (Roundup [Original]) were investigated regarding oxidative stress, the antioxidant defence system and acetylcholinesterase (AChE) activity in Drosophila melanogaster. Flies (of both genders) that were 1 to 3days old were exposed to different glyphosate concentrations (0.0mg/L=control, 1.0mg/L, 2.0mg/L, 5.0mg/L and 10.0mg/L) in the diet for 24h and 96h. After the exposure periods, reactive oxygen species (ROS) levels, antioxidant capacity against peroxyl radicals (ACAP) and lipid peroxidation (LPO) levels were quantified. In addition, the mRNA expression of antioxidant genes (i.e., keap1, sod, sod2, cat, irc, gclc, gclm, gss, trxt, trxr-1 and trxr-2) was evaluated via RT-PCR. Additionally, AChE activity was evaluated only after the 96h exposure period. The results indicated that Roundup exposure leads to a reduction in ROS levels in flies exposed for 96h. ACAP levels and gene expression of the antioxidant defence system exhibited an increase from 24h, while LPO did not show any significant alterations in both exposure periods. AChE activity was not affected following Roundup exposure. Our data suggest that Roundup exposure causes an early activation of the antioxidant defence system in D. melanogaster, and this can prevent subsequent damage caused by ROS. PMID:26980113
Full Text Available There is a rich body of work in critical race and feminist theories that have criticised as Euro/Anglo-centric, and hence exclusionary, the liberal foundations of Western democratic legal systems. The basis of such critiques is that legal personhood is premised on an atomistic individual agent that purports to be neutral but in actuality reflects and maintains the hegemonic gendered and raced status quo privileging the white, middle to upper-class man to the exclusion of women and all racial and cultural Others. Some approaches, such as cultural defences in criminal law, have sought to address this via a recognition and incorporation of the difference of Other groups and their different moral norms, proclivities and circumstances. To illustrate, this discussion will draw on a cultural defence that was advanced in a series of group sexual violence cases that involved four Pakistani, Muslim brothers. While concluding that culture permeates the actions of all individuals, this article seeks to show how cultural recognition approaches in law often overlook the individual agency of those differentiated through their racial, ethnic and religious visibility. Instead of asserting the primacy of individual free will and a rational agent as the main driver of criminal behaviour cultural defences, in particular, appear to attribute criminal action to the morally aberrant traditions and practices of non-Western cultures. At the same time, such approaches to cultural recognition fail to acknowledge that culture, and not just the culture of Others, is necessarily the backdrop for all (group sexual violence. With these points in mind, the paper ends with some suggestions for accommodating alternative narratives that seek to avoid the reductive scripts that currently appear to characterise legal and judicial musings on culture
Hu, Yang; Scheele, Dirk; Becker, Benjamin; Voos, Georg; David, Bastian; Hurlemann, René; Weber, Bernd
Humans display an intriguing propensity to help the victim of social norm violations or punish the violators which require theory-of-mind (ToM)/mentalizing abilities. The hypothalamic peptide oxytocin (OXT) has been implicated in modulating various pro-social behaviors/perception including trust, cooperation, and empathy. However, it is still elusive whether OXT also influences neural responses during third-party altruistic decisions, especially in ToM-related brain regions such as the temporo-parietal junction (TPJ). To address this question, we conducted a pharmacological functional magnetic resonance imaging experiment with healthy male participants in a randomized, double-blind, cross-over design. After the intranasal administration synthetic OXT (OXT(IN)) or placebo (PLC), participants could transfer money from their own endowment to either punish a norm violator or help the victim. In some trials, participants observed the decisions made by a computer. Behaviorally, participants under OXT(IN) showed a trend to accelerate altruistic decisions. At the neural level, we observed a strong three-way interaction between drug treatment (OXT/PLC), agency (self/computer), and decision (help/punish), such that OXT(IN) selectively enhanced activity in the left TPJ during observations of others being helped by the computer. Collectively, our findings indicate that OXT enhances prosocial-relevant perception by increasing ToM-related neural activations. PMID:26832991
Full Text Available Measures of sustainable behavior (SB usually include the self-report of activities aimed at the conservation of the natural environment. The sustainability notion explicitly incorporates both the satisfaction of human needs and the need of conserving the natural environment. Yet, the assessment of sustainable behaviors rarely considers the protection of the social environment as situation to investigate. In this paper, we propose the use of an instrument assessing SB, which includes the report of pro-ecological and frugal actions in addition to altruistic and equitable behaviors. The responses provided by 807 Mexican undergraduates to a questionnaire investigating those four instances of SB were processed within a structural equation model. Emotional (indignation due to environmental destruction, affinity towards diversity, happiness and rational (intention to act factors assumedly linked to sustainable behavior were also investigated. Significant interrelations among pro-ecological, frugal, altruistic and equitable behaviors resulted, suggesting the presence of a higher-order-factor that we identified as SB. This factor, in turn, significantly correlated with the rest of the investigated pro-environmental factors.
Full Text Available A peculiar irony characterizes the perception of global terrorism—in the strong penchant to flavor it with ethno or religious centric biases or in the disavowal of any auxiliary circumstance leading up to the sporadic incidence of violence. This paper analyzes the Mumbai attacks of November 26th, 2009 from the context of altruistic suicide/homicide. The waging of war against anonymous targets in Mumbai was by all means impersonal. It could be connected to an aftermath of several factors: Kashmir, homegrown terrorism, backlash of sectarian groups or yet another manifestation of already hostile Indo-Pak relationships. The spectacle of terror that was life telecast by national and global media led to a sequel of reactions including a follow-up of Indo-Pak mutual accusations, evoking of national sentiments and analytical ruptures in south Asian intelligentsia in making sense of the loss. This paper situates the Mumbai attacks of 26/11 in the theoretical discourse on sociology of terrorism by (i providing a scholastic definition of terrorism and its corresponding attributes that distinguishes terrorism from other sporadic acts of violence, (ii reflects on the context of terrorism with reference to altruism as in the classical Durkhiemian tradition and (iii analytically moves beyond the classical paradigm to redefine the terror trails of 26/11 within the emerging definitions of altruistic-suicide-homicide.
Hu, Yang; Scheele, Dirk; Becker, Benjamin; Voos, Georg; David, Bastian; Hurlemann, René; Weber, Bernd
Humans display an intriguing propensity to help the victim of social norm violations or punish the violators which require theory-of-mind (ToM)/mentalizing abilities. The hypothalamic peptide oxytocin (OXT) has been implicated in modulating various pro-social behaviors/perception including trust, cooperation, and empathy. However, it is still elusive whether OXT also influences neural responses during third-party altruistic decisions, especially in ToM-related brain regions such as the temporo-parietal junction (TPJ). To address this question, we conducted a pharmacological functional magnetic resonance imaging experiment with healthy male participants in a randomized, double-blind, cross-over design. After the intranasal administration synthetic OXT (OXTIN) or placebo (PLC), participants could transfer money from their own endowment to either punish a norm violator or help the victim. In some trials, participants observed the decisions made by a computer. Behaviorally, participants under OXTIN showed a trend to accelerate altruistic decisions. At the neural level, we observed a strong three-way interaction between drug treatment (OXT/PLC), agency (self/computer), and decision (help/punish), such that OXTIN selectively enhanced activity in the left TPJ during observations of others being helped by the computer. Collectively, our findings indicate that OXT enhances prosocial-relevant perception by increasing ToM-related neural activations. PMID:26832991
Gabriella D'Angelo; Sara Manti; Andrea Barbalace; Ignazio Barberi
Today, obesity represents one of the most serious health problems facing both children and adults. Childhood obesity has several causes, including genetic factors, dietary habits, personal behaviours, and interaction of all of these. It often leads to adult obesity, which causes health problems including heart disease, diabetes, and even early death. Thus, many studies have investigated possible measures to prevent childhood obesity, and breastfeeding is considered an important early preventi...
Full Text Available Abstract Background Behavioural syndromes, i.e. consistent individual differences in behaviours that are correlated across different functional contexts, are a challenge to evolutionary reasoning because individuals should adapt their behaviour to the requirements of each situation. Behavioural syndromes are often interpreted as a result of constraints resulting in limited plasticity and inflexible behaviour. Alternatively, they may be adaptive if correlated ecological or social challenges functionally integrate apparently independent behaviours. To test the latter hypothesis we repeatedly tested helpers in the cooperative breeder Neolamprologus pulcher for exploration and two types of helping behaviour. In case of adaptive behavioural syndromes we predicted a positive relationship between exploration and aggressive helping (territory defence and a negative relationship between these behaviours and non-aggressive helping (territory maintenance. Results As expected, helpers engaging more in territory defence were consistently more explorative and engaged less in territory maintenance, the latter only when dominant breeders were present. Contrary to our prediction, there was no negative relationship between exploration and territory maintenance. Conclusion Our results suggest that the three behaviours we measured are part of behavioural syndromes. These may be adaptive, in that they reflect strategic specialization of helpers into one of two different life history strategies, namely (a to stay and help in the home territory in order to inherit the breeding position or (b to disperse early in order to breed independently.
The topic of whether humans are altruistically motivated to behave in prosocial manner has been at the centre of debate for many years. Feeling empathy for another individual has been found to be crucial in the decision to act prosocially, for example, to help an individual in need. Additional antecedents of prosocial behaviour have been proposed, such as valuing another’s welfare (Batson & Eklund, 2007), perceived oneness the person in need and relationship to the person in need (Cialdini et...
Breant, Christian; Karock, Ulrich
Defence and security research have coexisted at the European Union level since the inception of the European Defence Agency (EDA). The agency was established under a Joint Action of the Council of Ministers on 12 July 2004, "to support the Member States and the Council in their effort to improve European defence capabilities in the field of crisis management and to sustain the European Security and Defence Policy as it stands now and develops in the future".1 The political decision to create the EDA was taken at the Thessaloniki European Council on 19 and 20 June 2003. Heads of State or Government tasked the Council bodies to undertake the requisite actions, in the course of 2004, to create an intergovernmental agency in the field of defence capabilities development, research, acquisition and armaments. The EDA has been located in Brussels right from the start. It is an intergovernmental EU agency under the Council's authority within the single institutional framework of the Union. It performs its mission in close cooperation with its participating Member States (pMS) and the European institutional actors.
Pentzold, Stefan; Zagrobelny, Mika; Roelsgaard, Pernille Sølvhøj;
Cyanogenic glucosides (CNglcs) are widespread plant defence compounds that release toxic hydrogen cyanide by plant bglucosidase activity after tissue damage. Specialised insect herbivores have evolved counter strategies and some sequester CNglcs, but the underlying mechanisms to keep CNglcs intact...... during feeding and digestion are unknown. We show that CNglc-sequestering Zygaena filipendulae larvae combine behavioural, morphological, physiological and biochemical strategies at different time points during feeding and digestion to avoid toxic hydrolysis of the CNglcs present in their Lotus food......, a highly alkaline midgut lumen inhibited the activity of ingested plant b-glucosidases significantly. Moreover, insect b-glucosidases from the saliva and gut tissue did not hydrolyse the CNglcs present in Lotus. The strategies disclosed may also be used by other insect species to overcome CNglc...
Mondet, Fanny; Kim, Seo Hyun; de Miranda, Joachim R; Beslay, Dominique; Le Conte, Yves; Mercer, Alison R
Social immunity forms an essential part of the defence repertoire of social insects. In response to infestation by the parasitic mite Varroa destructor and its associated viruses, honey bees (Apis mellifera L.) have developed a specific behaviour (varroa-sensitive hygiene, or VSH) that helps protect the colony from this parasite. Brood cells heavily infested with mites are uncapped, the brood killed, and the cell contents removed. For this extreme sacrifice to be beneficial to the colony, the targeting of parasitized brood for removal must be accurate and selective. Here we show that varroa-infested brood produce uniquely identifiable cues that could be used by VSH-performing bees to identify with high specificity which brood cells to sacrifice. This selective elimination of mite-infested brood is a disease resistance strategy analogous to programmed cell death, where young bees likely to be highly dysfunctional as adults are sacrificed for the greater good of the colony. PMID:27140530
In an economic sense defence expenditure is normally exogenously determined, that is economic forces do not play the leading role in determining the level of defense expenditure. Adam Smith, in his writing An Inquiry Into the Nature and Causes of the Wealth of Nations states that "It is only by means of a standing army therefore that the civilization of any country can be perpetuated or even preserved for any considerable time" (Canon, E., ed, 1976). A country can thus not supply defence, i.e...
Marisa Belausteguigoitia Rius; Mariana Gómez Alvarez Icaza; Iván González Márquez
Marisa Belausteguigoitia Rius, Mariana Gómez Alvarez Icaza and Iván González Márquez argue that indigenous and rural women play a leading role in the fight for the defence of their territories and its natural resources. They introduce the essays and testimonies of this section of the journal in order to show the complexity of the situation lived in Mexico, related to land, territory and the defence of natural resources, especially for indigenous women. In this context, they propose that indig...
Guillaume J. Dury
Full Text Available Cycloalexy was coined by Vasconcellos-Neto and Jolivet in 1988 and further defined by Jolivet and collaborators in 1990 in reference to a specific type of circular defence. The term has been applied to numerous organisms, including adult insects, nymphs, and even vertebrates, but has lost precision with the accumulation of anecdotal reports not addressing key elements of the behaviour as first defined. We review the literature and propose three criteria that are sufficient and necessary to define the behaviour: (1 individuals form a circle; (2 defensive attributes of the individuals are positioned on the periphery of the circle, and as a result, the periphery of the circle uniformly contains either heads or abdomens; (3 animals preemptively adopt the circle as a resting formation, meaning it is not necessary to observe predation. When these considerations are taken into account, cycloalexy appears less common in nature than the literature suggests. We argue that unequivocal cases of cycloalexy have been found only in sawflies (Tenthredinoidea: Pergidae, Argidae, leaf beetles (Chrysolemidae: Galerucinae, Cassidinae, Chrysomelinae, Criocerinae, weevils (Curculionidae: Phelypera distigma, and midges (Diptera: Ceratopogonidae, Forcipomyia. Reports of cycloalexy in caterpillars (Saturniidae: Hemileucinae: Lonomia, Papilionidae require further documentation. We report one new case of cycloalexy in thrips (Thysanoptera and question reports of cycloalexic behaviour in other taxa.
The defence industry has traditionally been a heavily regulated and protected market. A new EU Directive being implemented in Norway, January 2012, intends to reform the European defence market towards a higher degree of openness and liberalization. It is therefore vital for the Norwegian Government and national defence authorities to explore the impacts this new EU Directive will have in the near future. This thesis presents a computational agent-based model of the Norwegian defence industry...
Nabity, Paul D.; Zavala, Jorge A.; DeLucia, Evan H.
Herbivory initiates a shift in plant metabolism from growth to defence that may reduce fitness in the absence of further herbivory. However, the defence-induced changes in carbon assimilation that precede this reallocation in resources remain largely undetermined. This study characterized the response of photosynthesis to herbivore induction of jasmonic acid (JA)-related defences in Nicotiana attenuata to increase understanding of these mechanisms. It was hypothesized that JA-induced defences...
Aslanyan, Zaruhi; Nielson, Flemming
probability or cost of attacks and defences. In case of multiple parameters most analytical methods optimise one parameter at a time, e.g., minimise cost or maximise probability of an attack. Such methods may lead to sub-optimal solutions when optimising conflicting parameters, e.g., minimising cost while...
Mai, C.V.; Van Gelder, P.H.A.J.M.; Vrijling, J.K.; Mai, T.C.
This paper aims at risk analysis and the investigation of safety aspects of coastal flood defences in Vietnam. The sea dike system has been actually designed by a 20 to 25 years return period. From the current situation it seems that the dike system is not sufficient to withstand the actual sea boun
This paper outlines various features of the acquisition module of Sanjay, an augmented CDS/ISIS ver 2.3 software package. It briefly describes the activities which are carried out using this software at Defence Science Library. It also suggests some features that need to be provided for book acquisition processing.
-, č. 2 (2011), s. 33-56. ISBN 978-80-87488-17-1. ISSN 1805-0565 Institutional research plan: CEZ:AV0Z70680506 Keywords : use of force * self-defence * the UN Charter Subject RIV: AG - Legal Sciences
Following Fukushima Daiichi accident, the Defence-in-depth concept, which is usually defined as a combination of a number of consecutive and independent levels of protection that would have to fail before harmful effects could be caused, has been confirmed as an essential element to be applied in the design of a nuclear facility to protect people and the environment. However, and although the implementation of the defence in depth concept had been required for long, the Fukushima Daiichi accident and the “stress tests” conducted in different countries have revealed deficiencies in its implementation. Consequently within the review of the IAEA safety requirements requested by Member states, it was important to check whether this concept was appropriately defined in order to be properly understood and fully implemented by vendors and operating organizations. By screening the successive definitions of the defence in depth principle and concept, this paper emphasizes the few issues which have been gradually clarified and enhanced to ensure effectiveness of the defence in depth as expressed from its original statement. (author)
Bloemen, A.A.F.; Evers, L.; Barros, A.I.; Monsuur, H.; Wagelmans, A.P.M.
This paper proposes a model for determining a robust defence strategy against ballistic missile threat. Our approach takes into account a variety of possible future scenarios and different forms of robustness criteria, including the well-known absolute robustness criterion. We consider two problem v
Seoul: The Korean Society for Applied Biological Chemistry, 2012, s. 84-86. [2012 International Symposium and Annual Meeting of the KSABC. Gwangju (KR), 08.11.2012-10.11.2012] Institutional research plan: CEZ:AV0Z40550506 Keywords : insect communication * insect defence * pheromones Subject RIV: CC - Organic Chemistry
In this article, I indicate and illustrate several flaws in a recent "ethical defence" of homeopathy. It transpires that the authors' arguments have several features in common with homeopathic remedies, including strong claims, a lack of logic or evidence, and no actual effect. PMID:26659862
Soler, J J; Møller, A P; Soler, M
Some organisms enforce "maladaptive" behaviours on others of the same or different species by imposing costs in the absence of compliance. Such enforcement is used by the enforcer to obtain benefits in the possession of the enforced individual. This mechanism is known as mafia behaviour in humans, but may be widespread in parasite-host relationships in nature, from the cellular level to societies. In this paper we describe the evolution of such mafia mechanisms, and we propose a fuzzy logic model where the mafia mechanism is based on enforcement of hosts by exponentially increasing the cost of resistance to the parasite. The benefits of host resistance can be counteracted by parasite virulence, or even a decrease in response to an increment in its resistance. This parasite response to the host defence increment can be used for the parasite to teach the host that it is better to pay part of its benefits than increase its extremely costly defence. This model differs from others because it takes into account the evolution of host defence related to the evolution of parasite virulence (host-parasite coevolution) and points out an optimum in host defence related to the facultative virulence of the parasite. We provide several potential examples of facultative virulence depending on the antiparasite responses of hosts, and we suggest that this kind of mafia behaviour may be a widespread mechanism in biological processes at a number of different levels. PMID:9631567
Full Text Available Today, obesity represents one of the most serious health problems facing both children and adults. Childhood obesity has several causes, including genetic factors, dietary habits, personal behaviours, and interaction of all of these. It often leads to adult obesity, which causes health problems including heart disease, diabetes, and even early death. Thus, many studies have investigated possible measures to prevent childhood obesity, and breastfeeding is considered an important early preventive intervention. Despite the fact that several milk formulas have been demonstrated to be safe and effective for feeding both term and premature infants, for its immunological and nutritional qualitative advantages, human milk is nowadays universally recognized as the optimal feeding choice for healthy, sick and preterm infants. To date, it is however still unclear whether breastfeeding can prevent childhood obesity. In fact, literature data provide controversial results, probably due to several confounding factors, including maternal habits, age, level of education, lifestyle, race, parity, pregnancy complications, types of delivery, and infant health factors. Thus, whether breastfeeding protects against obesity is still unclear. Further researches, by reducing the influence of confounding factors and improving the accuracy of the effect estimate, are needed to confirm the validity of the role of breastfeeding in reducing the risk of developing childhood overweight. This review briefly summarizes what is known on the possible relationship between breastfeeding and prevention of obesity development.
Tait, Dorothy J
Previous research has shown that empathy and personality is related to helping behaviour. This study looks at helping in relation to affective empathy and Costa and McCrae’s (1992) Big Five personality traits, using both males (n = 22) and females (n = 32). It also looks at helping in relation to people’s dispositional levels of altruism, empathy and personal distress, which have not been widely looked at in previous research. These are measured before and after exposure to a help-provokin...
Fortin, Marie-Chantal; Dion-Labrie, Marianne; Hébert, Marie-Josée; Achille, Marie; Doucet, Hubert
It can be argued that living altruistic donors should remain anonymous and should not express preferences in the selection of organ recipients. This study aimed to describe the views of transplant physicians in France and Québec regarding these issues. A total of 27 French and 19 Québec renal transplant physicians took part in individual, semi-directed interviews. Almost all of the physicians agreed that anonymity is mandatory in living altruistic donation (LAD). Regarding the issue of directed donation, most of the French physicians (78%) were opposed to any form of the practice, compared to only a third of their Québec colleagues (32%). We found that these positions were embedded in their respective cultural, legal and social contexts. These results afford a better understanding of these complex issues in two different cultural contexts, and will be useful in the development of international guidelines for LAD. PMID:18406031
Bura, Veronica L; Kawahara, Akito Y; Yack, Jayne E
Caterpillars have long been used as models for studying animal defence. Their impressive armour, including flamboyant warning colours, poisonous spines, irritating sprays, and mimicry of plant parts, snakes and bird droppings, has been extensively documented. But research has mainly focused on visual and chemical displays. Here we show that some caterpillars also exhibit sonic displays. During simulated attacks, 45% of 38 genera and 33% of 61 species of silk and hawkmoth caterpillars (Bombycoidea) produced sounds. Sonic caterpillars are found in many distantly-related groups of Bombycoidea, and have evolved four distinct sound types- clicks, chirps, whistles and vocalizations. We propose that different sounds convey different messages, with some designed to warn of a chemical defence and others, to startle predators. This research underscores the importance of exploring acoustic communication in juvenile insects, and provides a model system to explore how different signals have evolved to frighten, warn or even trick predators. PMID:27510510
Rostás, Michael; Blassmann, Katrin
Insects have evolved an astonishing array of defences to ward off enemies. Well-known and widespread is the regurgitation of oral secretions (OS), fluids that repel attacking predators. In herbivores, the effectiveness of OS has been ascribed so far to the presence of deterrent secondary metabolites sequestered from the host plant. This notion implies, however, that generalists experience less protection on plants with low amounts of secondary metabolites or with compounds ineffective against...
Rostás, Michael; Blassmann, Katrin
Insects have evolved an astonishing array of defences to ward off enemies. Well known and widespread is the regurgitation of oral secretion (OS), fluid that repels attacking predators. In herbivores, the effectiveness of OS has been ascribed so far to the presence of deterrent secondary metabolites sequestered from the host plant. This notion implies, however, that generalists experience less protection on plants with low amounts of secondary metabolites or with compounds ineffective against ...
Choenni, R.S.; Leijnse, C.
The need for more efficiency in military organizations is growing. It is expected that a significant increase in efficiency can be obtained by an integration of communication and information technology. This integration may result in (sub)systems that are fully automated, i.e., systems that are unmanned, including unmanned vehicles. In this paper, we focus on the automation of air defence systems, in which integration of communication and information technology is a major issue. We propose an...
Leferink, F.B.J.; Malabiau, R.
The European Commission (EC) would like to improve the competitiveness of the European Defence Industry. The large number of (national) standards, more than 10.000, is recognised by EC as a major constraint and cost driver . Electromagnetic Compatibility (EMC) and more generally Electromagnetic Environmental Effects (EEE) have been considered by the EC as a major topic, with 7 other topics such as NBC detectors, energetic materials, fuels and lubricants, batteries, packaging, electrical an...
Bresson, Alain; Hunt, Andy; Tuomainen, Ari; Granbom, Bo; Urbanovsky, Claudia; Tredici, Claudio; Kugler, Dietmar; Leferink, Frank; Unden, Göran; Klok, Henk; Huguenin, Herve; Dymarkowski, Krzysztof; Popkowski, Jaroslaw; Lyomio, Jukka; Lodge, Keith
The European Commission (EC), DG Enterprise, endeavours the competitiveness of the European Defence Industry. The plethora of (national) standards, more than 10.000, are recognised by the EC as a major constraint and cost driver. Electromagnetic Compatibility (EMC) or Electromagnetic Environmental Effects (EEE) are considered by the EC as a major topic, with 7 other topics such as environmental engineering, energetic materials, batteries, electrical interfaces. An EMC expert group with repres...
Čeleda Pavel; Čegan Jakub; Vykopal Jan; Tovarňák Daniel
Correct and timely responses to cyber attacks are crucial for the effective implementation of cyber defence strategies and policies. The number of threats and ingenuity of attackers is ever growing, as is the need for more advanced detection tools, techniques and skilled cyber security professionals. KYPO – Cyber Exercise & Research Platform is focused on modelling and simulating complex computer systems and networks in a virtualized and separated environment. The platform enables realist...
It is well known that inhaled urban air contains many particles and gases. On the other hand, the anesthetic agents used in respiratory diseases comprise pharmaceutical particles. Deposition and cleaning processes of both the inhaled foreign particles and gases from room air, and inhalation agents from respiratory tract are very important clinically. These processes are carried out by the defense mechanisms of the respiratory system. In this review, the defence system of respiratory tract and...
This paper outlines various features of the acquisition module of Sanjay, an augmented CDS/ISIS ver 2.3 software package. It briefly describes the activities which are carried out using this software at Defence Science Library. It also suggests some features that need to be provided for book acquisition processing.http://dx.doi.org/10.14429/dbit.14.4.3103
Rostás, Michael; Blassmann, Katrin
Insects have evolved an astonishing array of defences to ward off enemies. Well known and widespread is the regurgitation of oral secretion (OS), fluid that repels attacking predators. In herbivores, the effectiveness of OS has been ascribed so far to the presence of deterrent secondary metabolites sequestered from the host plant. This notion implies, however, that generalists experience less protection on plants with low amounts of secondary metabolites or with compounds ineffective against ...
Gertrud Maria Hänsch
Bacteria living as biofilms have been recognised as the ultimate cause of persistent and destructive inflammatory processes. Biofilm formation is a well-organised, genetically-driven process, which is well characterised for numerous bacteria species. In contrast, the host response to bacterial biofilms is less well analysed, and there is the general believe that bacteria in biofilms escape recognition or eradication by the immune defence. In this review the host response to bacterial biofilms...
Lea Wiesel; Davis, Jayne L.; Linda Milne; Vanesa Redondo Fernandez; Herold, Miriam B.; Jill Middlefell Williams; Jenny Morris; Hedley, Pete E; Brian Harrower; Newton, Adrian C.; Birch, Paul R. J.; Gilroy, Eleanor M.; Ingo Hein
Phytohormones are involved in diverse aspects of plant life including the regulation of plant growth, development and reproduction, as well as governing biotic and abiotic stress responses. We have generated a comprehensive transcriptional reference map of the early potato responses to exogenous application of the defence hormones abscisic acid, brassinolides (applied as epibrassinolide), ethylene (applied as the ethylene precursor aminocyclopropanecarboxylic acid), salicylic acid and jasmoni...
Full Text Available Plant defence signalling response against various pathogens, including viruses, is a complex phenomenon. In resistant interaction a plant cell perceives the pathogen signal, transduces it within the cell and performs a reprogramming of the cell metabolism leading to the pathogen replication arrest. This work focuses on signalling pathways crucial for the plant defence response, i.e., the salicylic acid, jasmonic acid and ethylene signal transduction pathways, in the Arabidopsis thaliana model plant. The initial signalling network topology was constructed manually by defining the representation formalism, encoding the information from public databases and literature, and composing a pathway diagram. The manually constructed network structure consists of 175 components and 387 reactions. In order to complement the network topology with possibly missing relations, a new approach to automated information extraction from biological literature was developed. This approach, named Bio3graph, allows for automated extraction of biological relations from the literature, resulting in a set of (component1, reaction, component2 triplets and composing a graph structure which can be visualised, compared to the manually constructed topology and examined by the experts. Using a plant defence response vocabulary of components and reaction types, Bio3graph was applied to a set of 9,586 relevant full text articles, resulting in 137 newly detected reactions between the components. Finally, the manually constructed topology and the new reactions were merged to form a network structure consisting of 175 components and 524 reactions. The resulting pathway diagram of plant defence signalling represents a valuable source for further computational modelling and interpretation of omics data. The developed Bio3graph approach, implemented as an executable language processing and graph visualisation workflow, is publically available at http://ropot.ijs.si/bio3graph/and can be
Full Text Available Epichloë endophytes are common symbionts living asymptomatically in pooid grasses and may provide chemical defences against herbivorous insects. While the mechanisms underlying these fungal defences have been well studied, it remains unknown whether endophyte presence affects the host's own defences. We addressed this issue by examining variation in the impact of Epichloë on constitutive and herbivore-induced emissions of volatile organic compounds (VOC, a well-known indirect plant defence, between two grass species, Schedonorus phoenix (ex. Festuca arundinacea; tall fescue and Festuca pratensis (meadow fescue. We found that feeding by a generalist aphid species, Rhopalosiphum padi, induced VOC emissions by uninfected plants of both grass species but to varying extents, while mechanical wounding failed to do so in both species after one day of damage. Interestingly, regardless of damage treatment, Epichloë uncinata-infected F. pratensis emitted significantly lower quantities of VOCs than their uninfected counterparts. In contrast, Epichloë coenophiala-infected S. phoenix did not differ from their uninfected counterparts in constitutive VOC emissions but tended to increase VOC emissions under intense aphid feeding. A multivariate analysis showed that endophyte status imposed stronger differences in VOC profiles of F. pratensis than damage treatment, while the reverse was true for S. phoenix. Additionally, both endophytes inhibited R. padi population growth as measured by aphid dry biomass, with the inhibition appearing greater in E. uncinata-infected F. pratensis. Our results suggest, not only that Epichloë endophytes may play important roles in mediating host VOC responses to herbivory, but also that the magnitude and direction of such responses may vary with the identity of the Epichloë-grass symbiosis. Whether Epichloë-mediated host VOC responses will eventually translate into effects on higher trophic levels merits future investigation.
The UK Ministry of Defence's (MOD) publication Plutonium and Aldermaston: An Historical Account is a valuable report because it increases transparency and openness with regard to the UK's military fissile material holdings. The report does not fulfil the precise mandate set out in the government's 1998 Strategic Defence Review. The MOD then committed itself to providing an account of fissile material production. Instead, it has reported on fissile material transfers to and from the Atomic Weapons Establishment at Aldermaston (AWE) in the period 1952 to 1999. On 31 March 1999, the UK defence stockpile of plutonium comprised 3.51 tonnes. The report also discloses that physical stocks of plutonium at Aldermaston exceed recorded net deliveries to the site by 0.29 tonne (the inventory difference). The study reveals that the AWE acted as the centre of plutonium processing for both civilian and military programmes in the UK. The civilian work was largely phased out in the 1970s. To further increase transparency and meet stated disarmament objectives, the Department of Trade and Industry and MOD should launch a joint study of defence fissile material production, encompassing both plutonium and highly enriched uranium. A new table shows that the coverage of international safeguards in the UK is extensive. France is the only other state with a recognised nuclear weapon programme that approaches the UK in its safeguards coverage. The UK's withdrawals of fissionable material from safeguards since 1978 have recently been made public. It would be a significant step to strengthen safeguards if the UK were to announce that in the future it will not withdraw any nuclear material from international safeguards. (author)
Rodrigo Ferrada Stoehrel
In recent years, the Swedish Armed Forces have produced and distributed highly edited video clips on YouTube that show moving images of military activity. Alongside this development, mobile phone apps have emerged as an important channel through which the user can experience and take an interactive part in the staging of contemporary armed conflict. This article examines the way in which the aesthetic and affective experience of Swedish defence and security policy is socially and (media-)cult...
France and the UK face similar geostrategic circumstances: both were once Great Powers and still retain their positions among the five permanent members of the UN Security Council. During the Cold War both were dwarfed by the super-powers and were thus extremely sensitive about their status: what the French called their grandeur and the British called their seat at the top table. Despite their strategic similarities, they have differed in many of their defence policy choices and in particular...
Vermeij, Geerat J.
Predation is a primary agency of natural selection affecting the evolution of skeletal form in gastropods. The nature of antipredatory defence depends on how predators attack their prey as well as on the types and quantities of resources that are available to the potential victims. Here I review the five main methods of predation on shell-bearing gastropods (swallowing prey whole, apertural entry, drilling, shell breakage, and partial consumption) and 31 categories of shell and opercular defe...
Van der Ent, S.; Koornneef, A.; Ton, J.; Pieterse, C.M.J.
In nature, plants interact with a wide range of microbial pathogens and herbivorous insects. During the evolutionary arms race between plants and their attackers, primary and secondary immune responses evolved to recognise common or highly specialised features of the attacker encountered, resulting in sophisticated mechanisms of induced defence. Induced resistance mechanisms are characterised by a broad-spectrum effectiveness and often act systemically in plant parts distant from the site of ...
In the past, only two types of nuclear power plant instrumentation and control systems were in use in the Federal Republic of Germany (FRG): safety systems and operational systems. Present nuclear power plant 'Leittechnique' systems in the FRG have been expanded from this 'black-and-white' status to multiple-grade systems with respect to safety, qualification requirements and intelligence. The extensive experience of the past has encouraged the rule-making committees - representing all parties working in the nuclear field - to differentiate between the protection limitations and condition limitations of the reactor protection system on one hand and the information systems (including the accident monitoring and alarm system) of different safety importance on the other, assuming additional extensive application of non-safety-grade operational Leittechnique systems. These definitions of categories are in accordance with international practice and enable designers to apply 'echelons of defence', composed of equipment of all categories, in accordance with 'defence-in-depth' concepts. They also simplify the introduction of computerized equipment, especially in the lower safety categories. Status, background and reasons of the introduction, as well as typical defence-in-depth modes, of the first running Leittechnique system of this kind (in the Grafenrheinfeld nuclear power plant) and especially their different tasks in disturbance handling are described. The international situation and future developments are briefly characterized. (author)
Pollier, Jacob; Moses, Tessa; González-Guzmán, Miguel; De Geyter, Nathan; Lippens, Saskia; Vanden Bossche, Robin; Marhavý, Peter; Kremer, Anna; Morreel, Kris; Guérin, Christopher J; Tava, Aldo; Oleszek, Wieslaw; Thevelein, Johan M; Campos, Narciso; Goormachtig, Sofie; Goossens, Alain
Jasmonates are ubiquitous oxylipin-derived phytohormones that are essential in the regulation of many development, growth and defence processes. Across the plant kingdom, jasmonates act as elicitors of the production of bioactive secondary metabolites that serve in defence against attackers. Knowledge of the conserved jasmonate perception and early signalling machineries is increasing, but the downstream mechanisms that regulate defence metabolism remain largely unknown. Here we show that, in the legume Medicago truncatula, jasmonate recruits the endoplasmic-reticulum-associated degradation (ERAD) quality control system to manage the production of triterpene saponins, widespread bioactive compounds that share a biogenic origin with sterols. An ERAD-type RING membrane-anchor E3 ubiquitin ligase is co-expressed with saponin synthesis enzymes to control the activity of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), the rate-limiting enzyme in the supply of the ubiquitous terpene precursor isopentenyl diphosphate. Thus, unrestrained bioactive saponin accumulation is prevented and plant development and integrity secured. This control apparatus is equivalent to the ERAD system that regulates sterol synthesis in yeasts and mammals but that uses distinct E3 ubiquitin ligases, of the HMGR degradation 1 (HRD1) type, to direct destruction of HMGR. Hence, the general principles for the management of sterol and triterpene saponin biosynthesis are conserved across eukaryotes but can be controlled by divergent regulatory cues. PMID:24213631
Dipak K. Sahoo
Full Text Available Altered thyroid function during early stages of development is known to affect adversely testicular growth, physiology, and antioxidant defence status at adulthood. The objective of the present study is to investigate the modulation of antioxidant defence status in neonatal persistent hypothyroid rats before their sexual maturation and also to identify the specific testicular cell populations vulnerable to degeneration during neonatal hypothyroidism in immature rats. Hypothyroidism was induced in neonates by feeding the lactating mother with 0.05% 6-n-propyl-2-thiouracil (PTU through the drinking water. From the day of parturition till weaning (25 day postpartum, the pups received PTU through mother's milk (or drinking water and then directly from drinking water containing PTU for the remaining period of experimentation. On the 31st day postpartum, the animals were sacrificed for the study. An altered antioxidant defence system marked by elevated SOD, CAT, and GR activities, with decreased GPx and GST activities were observed along with increased protein carbonylation, disturbed redox status in hypothyroid immature rat testis. This compromised testicular antioxidant status might have contributed to poor growth and development by affecting the spermatogenesis and steroidogenesis in rats before puberty as indicated by reduced germ cell number, complete absence of round spermatids, decreased seminiferous tubule diameter, and decreased testosterone level.
Oji, S. I.
Full Text Available The study aimed at examining the practical operation of the right to private defence in Nigeria by virtue of the various constitutive legal instruments operating in the field of criminal jurisprudence. The sources of information relied upon here, are relevant statutes, texts, journals (both local and international and conference papers. The finding is that the enabling provisions on the subject matter are not smooth sailing. This is because the exercise of the right to private defence is further tied to the satisfaction of certain conditions which ordinarily the user will not advert his mind too and if case is not taken, in the attempt to prevent the commission of an offence which is about to be done to him, he becomes criminally liable in the reverse. In this regard, the study concluded that there is the problem of uncertainty as far as the instruments of self defence are concerned. In order to erase the problem of uncertainty, the user of the right must exercise caution in order to succeed in the courts, pending when an amendment is made.
Significant amounts of liquid and solid radioactive waste have been generated in Russia during the production of nuclear weapons, and there is an urgent need to find suitable ways to manage these wastes in a way that protects both the current population and future generations. This book contains contributions from pure and applied scientists and other representatives from Europe, North America, and Russia, who are, or have been, actively involved in the field of radioactive waste management and disposal. First-hand experience of specific problems associated with defence-related wastes in the USA and the Russian Federation is presented, and current plans are described for the disposal of solid wastes arising from civilian nuclear power production programmes in other countries, including Belgium, Bulgaria, Canada, Germany and the UK. The book provides a good insight into ongoing research at local and national level within Russia, devoted to the safe disposal of defence-related radioactive waste. It also demonstrates how existing expertise and technology from civilian nuclear waste management programmes can be applied to solving the problems created by nuclear defence programmes. Contributions address methods of immobilisation, site selection methodology, site characterisation techniques and data interpretation, the key elements of safety/performance assessments of planned deep (geological) repositories for radioactive waste, and radionuclide transport modelling. Concerns associated with certain specific nuclear waste disposal concepts and repository sites are also presented. refs
Hadzibeganovic, Tarik; Lima, F. Welington S.; Stauffer, Dietrich
An agent-based evolutionary model of tag-mediated altruism is studied on large-scale complex networks addressing multiplayer one-shot Prisoner’s Dilemma-like games with four competing strategies. Contrary to standard theoretical predictions, but in line with recent empirical findings, we observed that altruistic acts in non-repeated interactions can emerge as a natural consequence of recognition of heritable phenotypic traits such as visual tags, which enable the discrimination between potentially beneficial and unproductive encounters. Moreover, we identified topological regimes in which cooperation always prevails at short times, but where unconditional cooperators are favored over conditional tag-based helpers, even though the latter initially have a slight reproductive advantage. After very long times, we found that all four strategies appeared about equally often, meaning that only one quarter of agents refused cooperation egoistically. However, our study suggests that intra-tag generosity can quickly evolve to dominate over other strategies in spatially structured environments that are otherwise detrimental to cooperative behavior.
Mutyambai, Daniel M; Bruce, Toby J A; van den Berg, Johnnie; Midega, Charles A O; Pickett, John A; Khan, Zeyaur R
Attack of plants by herbivorous arthropods may result in considerable changes to the plant's chemical phenotype with respect to emission of herbivore-induced plant volatiles (HIPVs). These HIPVs have been shown to act as repellents to the attacking insects as well as attractants for the insects antagonistic to these herbivores. Plants can also respond to HIPV signals from other plants that warn them of impending attack. Recent investigations have shown that certain maize varieties are able to emit volatiles following stemborer egg deposition. These volatiles attract the herbivore's parasitoids and directly deter further oviposition. However, it was not known whether these oviposition-induced maize (Zea mays, L.) volatiles can mediate chemical phenotypic changes in neighbouring unattacked maize plants. Therefore, this study sought to investigate the effect of oviposition-induced maize volatiles on intact neighbouring maize plants in 'Nyamula', a landrace known to respond to oviposition, and a standard commercial hybrid, HB515, that did not. Headspace volatile samples were collected from maize plants exposed to Chilo partellus (Swinhoe) (Lepidoptera: Crambidae) egg deposition and unoviposited neighbouring plants as well as from control plants kept away from the volatile emitting ones. Behavioural bioassays were carried out in a four-arm olfactometer using egg (Trichogramma bournieri Pintureau & Babault (Hymenoptera: Trichogrammatidae)) and larval (Cotesia sesamiae Cameron (Hymenoptera: Braconidae)) parasitoids. Coupled Gas Chromatography-Mass Spectrometry (GC-MS) was used for volatile analysis. For the 'Nyamula' landrace, GC-MS analysis revealed HIPV production not only in the oviposited plants but also in neighbouring plants not exposed to insect eggs. Higher amounts of EAG-active biogenic volatiles such as (E)-4,8-dimethyl-1,3,7-nonatriene were emitted from these plants compared to control plants. Subsequent behavioural assays with female T. bournieri and C
Bode, Nikolai W. F.; Miller, Jordan; O'Gorman, Rick; Codling, Edward A.
Altruistic behaviour is widespread and highly developed in humans and can also be found in some animal species. It has been suggested that altruistic tendencies can depend on costs, benefits and context. Here, we investigate the changes in the occurrence of helping behaviour in a computer-based experiment that simulates an evacuation from a building exploring the effect of varying the cost to help. Our findings illuminate a number of key mechanistic aspects of human decision-making about whether to help or not. In a novel situation where it is difficult to assess the risks associated with higher costs, we reproduce the finding that increasing costs reduce helping and find that the reduction in the frequency of helping behaviour is gradual rather than a sudden transition for a threshold cost level. Interestingly, younger and male participants were more likely to help. We provide potential explanations for this result relating to the nature of our experiment. Finally, we find no evidence that participants in our experiment plan ahead over two consecutive, inter-dependent helping opportunities when conducting cost-benefit trade-offs in spontaneous decisions. We discuss potential applications of our findings to research into decision-making during evacuations.
Jonathan A. Lanman
Full Text Available Kognitivna istraživanja religije pokušavaju da objasne religijska uverenja. Ipak, mnogi antropolozi, psiholozi i filozofi kritikuju koncepte "vere" ili "uverenja" kao takve. Osnovne kritike sastoje se u tome da se "uverenje" ne može posmatrati, da ne postoji, i da je sam termin zapadnjački konstrukt neupotrebljiv za poređenje. Ove kritike mogu da učine da "nauka o verovanju" deluje naivno i pogrešno. Oslanjajući se na kognitivnu nauku, i filozofski funckionalizam koji joj je u osnovi, ponudiću minimalnu definiciju verovanja koja omogućuje nauci koja se time bavi da odoli ovim kritikama.
Lanman, Jonathan A.
Kognitivna istraživanja religije pokušavaju da objasne religijska uverenja. Ipak, mnogi antropolozi, psiholozi i filozofi kritikuju koncepte "vere" ili "uverenja" kao takve. Osnovne kritike sastoje se u tome da se "uverenje" ne može posmatrati, da ne postoji, i da je sam termin zapadnjački konstrukt neupotrebljiv za poređenje. Ove kritike mogu da učine da "nauka o verovanju" deluje naivno i pogrešno. Oslanjajući se na kognitivnu nauku, i filozofski funckionalizam koji joj je u osnovi, ponudić...
Benjamin L Hart
No other theme in animal biology seems to be more central than the concept of employing strategies to survive and successfully reproduce. In nature, controlling or avoiding pathogens and parasites is an essential fitness strategy because of the ever-present disease-causing organisms. The disease-control strategies discussed here are: physical avoidance and removal of pathogens and parasites; quarantine or peripheralization of conspecifics that could be carrying potential pathogens; herbal med...
Požgayová, Milica; Procházka, Petr; Honza, Marcel
Roč. 81, č. 1 (2009), s. 34-38. ISSN 0376-6357 R&D Projects: GA AV ČR IAA600930605; GA ČR(CZ) GD524/05/H536; GA MŠk LC06073 Institutional research plan: CEZ:AV0Z60930519 Keywords : Aggression * Cuckoo * Egg ejection * Great reed warbler * Nest guarding * Parental roles Subject RIV: EG - Zoology Impact factor: 1.527, year: 2009
Honza, Marcel; Grim, T.; Čapek Jr., Miroslav; Moksnes, A.; Roskaft, E.
Roč. 51, č. 3 (2004), s. 256-263. ISSN 0006-3657 R&D Projects: GA ČR GA206/00/P046; GA AV ČR IAA6093203; GA MŠk VS96019 Institutional research plan: CEZ:AV0Z6093917 Keywords : Cuculus canorus * brood parasitism * eggs Subject RIV: EG - Zoology Impact factor: 0.729, year: 2004 http://www.ingentaconnect.com/content/bto/bird/2004/00000051/00000003/art00009
Manuel Alberto M. Ferreira
It is intended in this work to review the book"Networks and Network Analysis for Defence and Security", 978-3-319-04146-9 published in Springer Series “Lecture Notes in Social Networks”. In this book the following areas are covered: Defence and security risk analysis; Criminal intelligence; Cyber crime;Cognitive analysis; Counter-terrorism and Social Network Analysis; Transnational Crime; Critical infrastructure analysis; Support to defence and security intelligence, emphasizing the idea that...
Doorduin, Leonie J.; Vrieling, Klaas
Several theories have been developed to explain why invasive species are very successful and develop into pest species in their new area. The shifting defence hypothesis (SDH) argues that invasive plant species quickly evolve towards new defence levels in the invaded area because they lack their specialist herbivores but are still under attack by local (new) generalist herbivores. The SDH predicts that plants should increase their cheap, toxic defence compounds and lower their expensive diges...
This report takes stock of the changes made to the European Security and Defence Policy since the adoption of the Lisbon Treaty in 2009. The report also examines what impact such changes have on Denmark, and specifically whether the Danish opt-out from EU defence cooperation will have increased consequences after the implementation of the Lisbon Treaty changes. By examining the Lisbon Treaty changes to the CSDP, and assessing how these affect Danish security and defence policy, the report pro...
Bankole, O O
Defence contracting has changed from the traditional provision of spares and repairs to contracting long-term for availability and capability. In these long-term contracts, the customer decides to outsource services (that would have been provided in-house) to contractors by consenting to an arrangement whereby payment is made only for the period that the equipment is made available to satisfy the defence need. Availability contracts may last for 40 years and more, but the main defence custome...
Huisken, Ron; Thatcher, Meredith
The fortieth anniversary of the Strategic and Defence Studies Centre’s founding provided the opportunity to assemble many of Australia’s leading analysts and commentators to review some of the more significant issues that should define Australian defence policy. In the first 20 years after its establishment, SDSC scholars played a prominent role in shaping the ideas and aspirations that eventually found official expression in the 1987 Defence of Australia White Paper. This policy sustaine...
Rasher, Douglas B; Hay, Mark E.
Many seaweeds and terrestrial plants induce chemical defences in response to herbivory, but whether they induce chemical defences against competitors (allelopathy) remains poorly understood. We evaluated whether two tropical seaweeds induce allelopathy in response to competition with a reef-building coral. We also assessed the effects of competition on seaweed growth and seaweed chemical defence against herbivores. Following 8 days of competition with the coral Porites cylindrica, the chemica...
Houston, Alasdair I; Mcnamara, John M.; Barta, Zoltán; Klasing, Kirk C
In order to avoid both starvation and disease, animals must allocate resources between energy reserves and immune defence. We investigate the optimal allocation. We find that animals with low reserves choose to allocate less to defence than animals with higher reserves because when reserves are low it is more important to increase reserves to reduce the risk of starvation in the future. In general, investment in immune defence increases monotonically with energy reserves. An exception is when...
Hoetzl Thomas; Ruether Matthias; Weihmann Frank; Maurer Michael; Kastberger Gerald; Kranner Ilse; Bischof Horst
Abstract Background The detailed interpretation of mass phenomena such as human escape panic or swarm behaviour in birds, fish and insects requires detailed analysis of the 3D movements of individual participants. Here, we describe the adaptation of a 3D stereoscopic imaging method to measure the positional coordinates of individual agents in densely packed clusters. The method was applied to study behavioural aspects of shimmering in Giant honeybees, a collective defence behaviour that deter...
The 80th anniversary of civil defence in Russia was marked by the All-Russian civil defence exercise attended by representatives of federal executive authorities, regional and local executive authorities. During the exercise performance of the following activities was verified: introduction of increased preparedness mode for local air-defence emergency-response forces, activities of emergency-response and fire safety commissions, information collection and exchange during implementation of top-priority civil defence measures, etc. The paper describes the activities carried out during the exercise
Göran M Nylund
Full Text Available A number of studies have shown that the production of chemical defences is costly in terrestrial vascular plants. However, these studies do not necessarily reflect the costs of defence production in macroalgae, due to structural and functional differences between vascular plants and macroalgae. Using a specific culturing technique, we experimentally manipulated the defence production in the red alga Bonnemaisonia hamifera to examine if the defence is costly in terms of growth. Furthermore, we tested if the defence provides fitness benefits by reducing harmful bacterial colonisation of the alga. Costly defences should provide benefits to the producer in order to be maintained in natural populations, but such benefits through protection against harmful bacterial colonisation have rarely been documented in macroalgae. We found that algae with experimentally impaired defence production, but with an externally controlled epibacterial load, grew significantly better than algae with normal defence production. We also found that undefended algae exposed to a natural epibacterial load experienced a substantial reduction in growth and a 6-fold increase in cell bleaching, compared to controls. Thus, this study provides experimental evidence that chemical defence production in macroalgae is costly, but that the cost is outweighed by fitness benefits provided through protection against harmful bacterial colonisation.
Swadhin Swain; Nidhi Singh; Ashis Kumar Nandi
A sustainable balance between defence and growth is essential for optimal fitness under pathogen stress. Plants activate immune response at the cost of normal metabolic requirements. Thus, plants that constitutively activate defence are deprived of growth. Arabidopsis thaliana mutant constitutive defence without defect in growth and development1 (cdd1) is an exception. The cdd1 mutant is constitutive for salicylic acid accumulation, signalling, and defence against biotrophic and hemibiotrophic pathogens, without having much impact on growth. Thus, cdd1 offers an ideal genetic background to identify novel regulators of plant defence. Here we report the differential gene expression profile between cdd1 and wild-type plants as obtained by microarray hybridization. Expression of several defence-related genes also supports constitutive activation of defence in cdd1. We screened T-DNA insertion mutant lines of selected genes, for resistance against virulent bacterial pathogen Pseudomonas syringae pv. tomato DC3000 (Pst DC3000). Through bacterial resistance, callose deposition and pathogenesis-associated expression analyses, we identified four novel regulators of plant defence. Resistance levels in the mutants suggest that At2g19810 and [rom] At5g05790 are positive regulators, whereas At1g61370 and At3g42790 are negative regulators of plant defence against bacterial pathogens.
Safety management is a kind of system management, that is management by purposes. Taking "defence-in-depth" strategy, DDS - there can be defined four main aims and four method groups of risk management in transport: 1. minimizing transport accidents risk; 2. minimizing number of undesirable transport events (incidents, conflicts, collisions, accidents). Above purposes relate stages of safety management in transport. At each level of management should be elaborated methods, procedures and technologies of minimizing transport accidents risk. According to DDS any management system of transport safety should have a structure of multilevel chain protections which supervise main transport processes. About those problems in the paper.
Lapkova, Dora; Adamek, Milan
This paper is focused on analysis of a direct punch. Nowadays, professional defence is basic part of effective protection of people and property. There are many striking techniques and the goal of this research was to analyze the direct punch. The analysis is aimed to measure the velocity with help of high speed camera Olympus i-Speed 2 and then find the dependences of this velocity on input parameters. For data analysis two pieces of software were used - i-Speed Control Software and MINITAB. 111 participants took part in this experiment. The results are presented in this paper - especially dependence of mean velocity on time and difference in velocity between genders.
Kluth, Michael Friederich
The European Defence Industry is undergoing consolidation cutting across national borders. This is spurred by European Union policy initiatives and active encouragement by some national governments fearing a US-led global consolidation of the industry. The process in many ways proves challenging as...... paper will depart from these institutional peculiarities drawing on the varieties of capitalism literature. Different patterns in ownership, public-private R&D links and business promotion policies are a key constraint in cross-border mergers. This is compounded by sovereignty concerns hosted by the...
-Prevention of suicidal behaviour remains difficult, despite increasing knowledge of its determinants. Health service efforts hardly affect suicide rates. -Recent shifts in the epidemiology of suicidal behaviour are rising rates among the young and increasing use of violent methods. these can be lin
I tested the hypothesis that mobbing chiefly functions as a nest defence mechanism by studying the mobbing behaviour of two species of drongo (black drongo Dicrurus macrocercus and ashy drongo D. leucophaeus) towards two species of raptor in rain forest of western Java, Indonesia. It was predicted t
Schorkopf, Dirk Louis P; Hrncir, Michael; Mateus, Sidnei; Zucchi, Ronaldo; Schmidt, Veronika M; Barth, Friedrich G
Like ants and termites some species of stingless bees (Meliponini), which are very important pollinators in the tropics, use pheromone trails to communicate the location of a food source. We present data on the communicative role of mandibular gland secretions of Meliponini that resolve a recent controversy about their importance in the laying of such trails. Volatile constituents of the mandibular glands have been erroneously thought both to elicit aggressive/defensive behaviour and to signal food source location. We studied Trigona spinipes and Scaptotrigona aff. depilis ('postica'), two sympatric species to which this hypothesis was applied. Using extracts of carefully dissected glands instead of crude cephalic extracts we analysed the substances contained in the mandibular glands of worker bees. Major components of the extracts were 2-heptanol (both species), nonanal (T. spinipes), benzaldehyde and 2-tridecanone (S. aff. depilis). The effect of mandibular gland extracts and of individual components thereof on the behaviour of worker bees near their nest and at highly profitable food sources was consistent. Independent of the amount of mandibular gland extract applied, the bees overwhelmingly reacted with defensive behaviour and were never attracted to feeders scented with mandibular gland extract or any of the synthetic chemicals tested. Both bee species are capable of using mandibular gland secretions for intra- and interspecific communication of defence and aggression and share 2-heptanol as a major pheromone compound. While confirming the role of the mandibular glands in nest defence, our experiments provide strong evidence against their role in food source signalling. PMID:19329748
González-Teuber, Marcia; Kaltenpoth, Martin; Boland, Wilhelm
Mutualistic ants are commonly considered as an efficient indirect defence against herbivores. Nevertheless, their indirect protective role against plant pathogens has been scarcely investigated. We compared the protective role against pathogens of two different ant partners, a mutualistic and a parasitic ant, on the host plant Acacia hindsii (Fabaceae). The epiphytic bacterial community on leaves was evaluated in the presence and absence of both ant partners by cultivation and by 454 pyrosequencing of the 16S rRNA gene. Pathogen-inflicted leaf damage, epiphytic bacterial abundance (colony-forming units) and number of operational taxonomic units (OTUs) were significantly higher in plants inhabited by parasitic ants than in plants inhabited by mutualistic ants. Unifrac unweighted and weighted principal component analyses showed that the bacterial community composition on leaves changed significantly when mutualistic ants were removed from plants or when plants were inhabited by parasitic ants. Direct mechanisms provided by ant-associated bacteria would contribute to the protective role against pathogens. The results suggest that the indirect defence of mutualistic ants also covers the protection from bacterial plant pathogens. Our findings highlight the importance of considering bacterial partners in ant-plant defensive mutualisms, which can contribute significantly to ant-mediated protection from plant pathogens. PMID:24392817
The idea that a study of the humanities helps to humanise doctors has become a leitmotif within the field. It is argued that the humanities (especially, literature) help to foster insights beyond those provided by biomedical training. Healthy young medics, it is claimed, can thereby gain significant insights into patienthood, and obtain important skills that may be valuable for their professional life. But the instrumentality of the humanities is not the only justification proffered for its inclusion in medical curricula. In this paper I critically examine the two overarching justifications recurrently cited in the mainstream literature-namely, (1) the instrumental worth and (2) the intrinsic value of the medical humanities in educating doctors. Examining these theses (and focusing on the views of a leading medical humanities scholar) I show that the bifurcation into instrumental versus non-instrumental justifications is not supported by the argumentation. Instead, I find that the particulars of the supposedly intrinsic justifications amount to an unambiguously instrumental defence of the humanities. Contextualizing the present investigation to probe further, I describe a long history of debate about the role of the humanities in British education and find that it rests on unsupported dichotomies (utility vs non-utility, theoretical vs applied, educated vs trained). I conclude that the medical humanities' manifesto would be more intellectually honest and coherent, and provide a more robust defence of its value in medical education, if it chose to embrace a wholly instrumental rationale for its role. PMID:26842744
Altruistic punishment means that individuals punish, although the punishment is costly for them and yields no material gain. Recent research found that penalizing rule-breakers activated a brain region called the dorsal striatum, which is involved in experiencing pleasure or satisfaction. And researchers suggested the outcome of altruistic punishment should be equivalent to the money rewards. At this point the researchers had discovered a correlation - that the pleasure-related brain activity occurred along with inflicting the punishment - but a deeper question remained: Did one experience cause the other? Further experiments indicated that inflicting the punishment didn't cause the players to feel satisfaction. Instead, as they decided to impose the penalty, the players were anticipating feeling satisfied. Besides, these studies concerned the decision making, rather than the feedback outcome itself. Therefore, it is not clear how humans evaluate the outcome of altruistic punishment?Study 1 using single trust game to ask the subjects to evaluate their emotions between the "the outcome before the punishment" and "the outcome after the punishment", " the outcome of cooperation" and " the outcome of the altruistic punishment", the "the outcome of the altruistic punishment" and "the outcome of the non-punishment" have found positive emotions increased and negative emotions weakened after the altruistic punishment compared to the outcome before the punishment. However, the pleasant feelings from the outcome of the altruistic punishment were still far below that from the outcome of the cooperation and higher than that of "the outcome of the non-punishment". And both outcome of altruistic punishment and non-punishment were biased negative emotions, and non-punishment lower ratings. The degree of negative emotions caused by "non-punishment" was greater than "punishment".Study 2 using event related brain potentials studied the evaluative processes in the brain when subjects
Olsen, Gorm Rye
thesis. The article shows that in spite of the opt-out, the administrative structures and the policy processes in the Ministry of Foreign Affairs (MFA) have adapted to the common foreign and security policy (CFSP) and the European security and defence policy (ESDP). Surprisingly, the administrative......The article questions how strong Europeanisation is as an explanation of administrative changes in EU member states. Denmark has an opt-out from the European cooperation on defence, and, therefore, its defence administration represents a critical or a less likely case to test the Europeanisation...... structures and the decision-making processes in the Ministry of Defence (MoD) have also adapted to the ESDP. The latter example emphasises the strength of top-down Europeanisation as a possible explanation of domestic administrative changes in member states. It is argued that Europeanisation per se is not an...
R.P.L. Louwen (Rogier); P. van Baarlen (Peter)
textabstractThe continuous battle for survival in the environment has led to the development or acquisition of sophisticated defence systems in bacteria. These defence systems have contributed to the survival of the bacterial species in the environment for millions of years. Some systems appear to h
Louwen, R.; Baarlen, van P.
The continuous battle for survival in the environment has led to the development or acquisition of sophisticated defence systems in bacteria. These defence systems have contributed to the survival of the bacterial species in the environment for millions of years. Some systems appear to have evolved
In 2015 the South African Parliament finalised the long awaited new defence review. This document had been a long time in the making and was the result of more than four years of intensive work by the members of the Defence Review Committee. The recommendations envisage an extensive transformatio...
Nour-Eldin, Hussam Hassan; Andersen, Tonni Grube; Burow, Meike;
In plants, transport processes are important for the reallocation of defence compounds to protect tissues of high value, as demonstrated in the plant model Arabidopsis, in which the major defence compounds, glucosinolates, are translocated to seeds on maturation. The molecular basis for long-dist...
The work of the Civil Defence Commission comprises also interdisciplinary questions of civil defence and disaster relief. The lectures are concerned with the causes and effects of radioactivity, medical practice in the event of disaster, toxicology and pathology, including even psychology in disaster as well as risk management and dosimetry. The subjects chemical accidents and disaster relief are marginally dealt with. (DG)
Firth, L.B.; Thompson, R.C.; Bohn, K.; Abbiati, M.; Airoldi, L.; Bouma, T.J.; Bozzeda, F.; Ceccherelli, V.U.; Colangelo, M.A.; Evans, A.; Ferrario, F.; Hanley, M.E.; Hinz, H.; Hoggart, S.P.G.; Jackson, J.E.; Moore, P.; Morgan, E.H.; Perkol-Finkel, S.; Skov, M.W.; Strain, E.M.; van Belzen, J.; Hawkins, S.J.
Coastal defence structures are proliferating as a result of rising sea levels and stormier seas. With the realisation that most coastal infrastructure cannot be lost or removed, research is required into ways that coastal defence structures can be built to meet engineering requirements, whilst also
Newman, D. W.; Beail, N.
Problem: A significant concept in psychodynamic theory and practice is that of defence mechanisms. The identifications of defences is a key task of the therapist and these are then used in the formulation and form part of the therapist's interventions. Case studies of psychotherapy with adults who have intellectual disabilities (IDs) suggest that…
Zhang, Ziguo; Feechan, Angela; Pedersen, Carsten;
Penetration resistance is often the first line of defence against fungal pathogens. Subsequently induced defences are mediated by the programmed cell death (PCD) reaction pathway and the salicylic acid (SA), jasmonic acid (JA) and ethylene (ET) signalling pathways. We previously demonstrated...
Griggio, Matteo; Matessi, Giuliano; Pilastro, Andrea
-old nestlings, and measured the intensity of male and female defence reaction. We measured the frequency of attack flights, intensity of alarm calling and total time spent in view, and then combined these for each individual, in a single defence factor by principal component analysis. All the females arrived to...
Uhl, Lionel; Dukan, Sam
We recently developed a mathematical model for predicting reactive oxygen species (ROS) concentration and macromolecules oxidation in vivo. We constructed such a model using Escherichia coli as a model organism and a set of ordinary differential equations. In order to evaluate the major defences relative roles against hydrogen peroxide (H2 O2), we investigated the relative contributions of the various reactions to the dynamic system and searched for approximate analytical solutions for the explicit expression of changes in H2 O2 internal or external concentrations. Although the key actors in cell defence are enzymes and membrane, a detailed analysis shows that their involvement depends on the H2 O2 concentration level. Actually, the impact of the membrane upon the H2 O2 stress felt by the cell is greater when micromolar H2 O2 is present (9-fold less H2 O2 in the cell than out of the cell) than when millimolar H2 O2 is present (about 2-fold less H2 O2 in the cell than out of the cell). The ratio between maximal external H2 O2 and internal H2 O2 concentration also changes, reducing from 8 to 2 while external H2 O2 concentration increases from micromolar to millimolar. This non-linear behaviour mainly occurs because of the switch in the predominant scavenger from Ahp (Alkyl Hydroperoxide Reductase) to Cat (catalase). The phenomenon changes the internal H2 O2 maximal concentration, which surprisingly does not depend on cell density. The external H2 O2 half-life and the cumulative internal H2 O2 exposure do depend upon cell density. Based on these analyses and in order to introduce a concept of dose response relationship for H2 O2-induced cell death, we developed the concepts of “maximal internal H2 O2 concentration” and “cumulative internal H2 O2 concentration” (e.g. the total amount of H2 O2). We predict that cumulative internal H2 O2 concentration is responsible for the H2 O2-mediated death of bacterial cells. PMID:27494019
Uhl, Lionel; Dukan, Sam
We recently developed a mathematical model for predicting reactive oxygen species (ROS) concentration and macromolecules oxidation in vivo. We constructed such a model using Escherichia coli as a model organism and a set of ordinary differential equations. In order to evaluate the major defences relative roles against hydrogen peroxide (H2 O2), we investigated the relative contributions of the various reactions to the dynamic system and searched for approximate analytical solutions for the explicit expression of changes in H2 O2 internal or external concentrations. Although the key actors in cell defence are enzymes and membrane, a detailed analysis shows that their involvement depends on the H2 O2 concentration level. Actually, the impact of the membrane upon the H2 O2 stress felt by the cell is greater when micromolar H2 O2 is present (9-fold less H2 O2 in the cell than out of the cell) than when millimolar H2 O2 is present (about 2-fold less H2 O2 in the cell than out of the cell). The ratio between maximal external H2 O2 and internal H2 O2 concentration also changes, reducing from 8 to 2 while external H2 O2 concentration increases from micromolar to millimolar. This non-linear behaviour mainly occurs because of the switch in the predominant scavenger from Ahp (Alkyl Hydroperoxide Reductase) to Cat (catalase). The phenomenon changes the internal H2 O2 maximal concentration, which surprisingly does not depend on cell density. The external H2 O2 half-life and the cumulative internal H2 O2 exposure do depend upon cell density. Based on these analyses and in order to introduce a concept of dose response relationship for H2 O2-induced cell death, we developed the concepts of "maximal internal H2 O2 concentration" and "cumulative internal H2 O2 concentration" (e.g. the total amount of H2 O2). We predict that cumulative internal H2 O2 concentration is responsible for the H2 O2-mediated death of bacterial cells. PMID:27494019
Nicholas A Paul
Full Text Available All of the theory and most of the data on the ecology and evolution of chemical defences derive from terrestrial plants, which have considerable capacity for internal movement of resources. In contrast, most macroalgae--seaweeds--have no or very limited capacity for resource translocation, meaning that trade-offs between growth and defence, for example, should be localised rather than systemic. This may change the predictions of chemical defence theories for seaweeds. We developed a model that mimicked the simple growth pattern of the red seaweed Asparagopsis armata which is composed of repeating clusters of somatic cells and cells which contain deterrent secondary chemicals (gland cells. To do this we created a distinct growth curve for the somatic cells and another for the gland cells using empirical data. The somatic growth function was linked to the growth function for defence via differential equations modelling, which effectively generated a trade-off between growth and defence as these neighbouring cells develop. By treating growth and defence as separate functions we were also able to model a trade-off in growth of 2-3% under most circumstances. However, we found contrasting evidence for this trade-off in the empirical relationships between growth and defence, depending on the light level under which the alga was cultured. After developing a model that incorporated both branching and cell division rates, we formally demonstrated that positive correlations between growth and defence are predicted in many circumstances and also that allocation costs, if they exist, will be constrained by the intrinsic growth patterns of the seaweed. Growth patterns could therefore explain contrasting evidence for cost of constitutive chemical defence in many studies, highlighting the need to consider the fundamental biology and ontogeny of organisms when assessing the allocation theories for defence.
Yamazaki, Hiroshi; Fuchs, Steffen; Takada, Toshiaki; Kataoka, Kazuyoshi [Toshiba International Limited (Japan)
The current defence-in-depth (DiD) concept has been established by the Reactor Harmonization Working Group (RHWG) of Western European Nuclear Regulators Association (WENRA). Principally the DiD concept was already part of the very early power reactor designs. However, additional considerations have been done in order to take plant conditions into account which are beyond the original design basis. The most recent advancements have been done based on major lessons learned from the Fukushima Dai-Ichi accident. Especially for new nuclear reactors it has to be demonstrated that DiD aspects have been considered in their design. Currently Toshiba is adapting its Advanced Boiling Water Reactor (ABWR) for the European market, at first in Finland. This presentation aims to describe how the new DiD concept has been applied to achieve the safety goals for a modern reactor type and to ensure a design that can be licensed in Western Europe. (orig.)
Mastronicola, Daniela; Falabella, Micol; Forte, Elena; Testa, Fabrizio; Sarti, Paolo; Giuffrè, Alessandro
The microaerophilic protist Giardia intestinalis is the causative agent of giardiasis, one of the most common intestinal infectious diseases worldwide. The pathogen lacks not only respiratory terminal oxidases (being amitochondriate), but also several conventional antioxidant enzymes, including catalase, superoxide dismutase and glutathione peroxidase. In spite of this, since living attached to the mucosa of the proximal small intestine, the parasite should rely on an efficient antioxidant system to survive the oxidative and nitrosative stress conditions found in this tract of the human gut. Here, we review current knowledge on the antioxidant defence systems in G. intestinalis, focusing on the progress made over the last decade in the field. The relevance of this research and future perspectives are discussed. PMID:26672398
Craik, David J
Cyclotides are ultra-stable plant proteins that have a circular peptide backbone crosslinked by a cystine knot of disulfide bonds. They are produced in large quantities by plants of the Violaceae and Rubiaceae families and have a role in plant defence against insect predation. As I discuss here, recent studies have begun to reveal how their unique circular topology evolved. Cyclization is achieved by hijacking existing plant proteolytic enzymes and operating them in 'reverse' to form a peptide bond between the N- and C-termini of a linear precursor. Such studies suggest that circular proteins are more common in the plant kingdom than was previously thought, and their exceptional stability has led to their application as protein-engineering templates in drug design. PMID:19423383
B. B. Chaudhuri
Full Text Available The tremendous development in remote sensing technology in the recent past has opened up new challenges in defence applications. On important area of such applications is in target detection. This paper describes both classical and newly developed approaches to detect the targets by using remotely-sensed digital images. The classical approach includes statistical classification methods and image processing techniques. The new approach deals with a relatively new sensor technology, namely, synthetic aperture radar (SAR systems and fast developing tools, like neural networks and multisource data integration for analysis and interpretation. With SAR images, it is possible to detect targets or features of a target that is otherwise not possible. Neural networks and multisource data integration tools also have a great potential in analysing and interpreting remote sensing data for target detection.
Ølykke, Grith Skovgaard
court’s perception. As the contracts had been declared to be in force by a declaratory judgment that was res judicata, the dispute before the CJEU concerned the national interpretation of the principle of res judicata and its application in a State aid context. The CJEU first turned to the principle of......In the annotated judgment a public authority uses the existence of State aid as a defence in a legal action, where its contractual partner aimed to achieve damages and fulfilment of the contracts. The public authority claimed that the contracts were not on market terms, which also was the national...... consistent interpretation, which it considered could provide various solutions for the national court to draw all the necessary consequences of the possible breach of the duty to notify State aid. In the alternative, the CJEU considered the principle of effectiveness and found that due to the fundamental...
Full text: Training personnel in ionising radiation safety within the Australian Defence Organisation (ADO) requires addressing some unique features of an organisation employing both military and civilian personnel. Activities may include those of a civil nature (such as industrial and medical radiography), specific military requirements (for training and emergency response) and scientific research and development. Some personnel may be assigned to full-time duties associated with radiation, while others may be designated as radiation protection officers in remote units with few duties to perform in this role. A further complication is that most military personnel are subjected to postings at regular intervals. The ADO's Directorate of Defence Occupational Health and Safety has established an Ionising Radiation Safety Subcommittee to monitor not only the adequacy of the internal Ionising Radiation Safety Manual but also the training requirements. A training course, responding to these requirements, has been developed to emphasise: basic radiation theory and protection; operation of radiation monitors available in the ADO; an understanding of the Safety Manual; day-to-day radiation safety in units and establishments; and appropriate responses to radiation accidents and emergencies. In addition, students are briefed on a limited number of peripheral topics and participate in some site visits. Currently, two Courses are held annually, each with about twenty students. Most of the material is presented by ADO personnel with external contractor support. The three Courses held to date have proved sufficiently successful, both for the students and the ADO generally, to seek national accreditation through the Australian National Training Authority and, as a first step, competency standards have been identified
Training personnel in ionising radiation safety within the Australian Defence Organisation (ADO) requires addressing some unique features of an organisation employing both military and civilian personnel. Activities may include those of a civil nature (such as industrial and medical radiography), specific military requirements (for training and emergency response) and scientific research and development. Some personnel may be assigned to full-time duties associated with radiation. However, most are designated as radiation protection officers as a secondary duty. A further complication is that most military personnel are subjected to postings at regular intervals. The ADO's Directorate of Defence Occupational Health and Safety has established an Ionising Radiation Safety Subcommittee to monitor not only the adequacy of the internal Ionising Radiation Safety Manual but also the training requirements. A Training Course, responding to these requirements, has been developed to emphasize, basic radiation theory and protection, operation of radiation monitors available in the ADO, an understanding of the Ionising Radiation Safety Manual, day-to-day radiation safety in units and establishments, and appropriate responses to radiation accidents and emergencies. In addition, students are briefed on a limited number of peripheral topics and participate in some site visits. Currently, two Courses are held annually, each with about twenty students. Most of the material is presented by ADO personnel with external contractor support. The three Courses held to date have proved successful, both for the students and the ADO generally. To seek national accreditation of the course through the Australian National Training Authority, as a first step, competency standards have been proposed. (authors)
Gorzelak, Monika A.; Asay, Amanda K.; Pickles, Brian J.; Simard, Suzanne W.
Adaptive behaviour of plants, including rapid changes in physiology, gene regulation and defence response, can be altered when linked to neighbouring plants by a mycorrhizal network (MN). Mechanisms underlying the behavioural changes include mycorrhizal fungal colonization by the MN or interplant communication via transfer of nutrients, defence signals or allelochemicals. We focus this review on our new findings in ectomycorrhizal ecosystems, and also review recent advances in arbuscular mycorrhizal systems. We have found that the behavioural changes in ectomycorrhizal plants depend on environmental cues, the identity of the plant neighbour and the characteristics of the MN. The hierarchical integration of this phenomenon with other biological networks at broader scales in forest ecosystems, and the consequences we have observed when it is interrupted, indicate that underground ‘tree talk’ is a foundational process in the complex adaptive nature of forest ecosystems. PMID:25979966
Full Text Available In humans and other mammals, drugs of abuse alter the function of biogenic amine pathways in the brain leading to the subjective experience of reward and euphoria. Biogenic amine pathways are involved in reward processing across diverse animal phyla, however whether cocaine acts on these neurochemical pathways to cause similar rewarding behavioural effects in animal phyla other than mammals is unclear. Previously, it has been shown that bees are more likely to dance (a signal of perceived reward when returning from a sucrose feeder after cocaine treatment. Here we examined more broadly whether cocaine altered reward-related behaviour, and biogenic amine modulated behavioural responses in bees. Bees developed a preference for locations at which they received cocaine, and when foraging at low quality sucrose feeders increase their foraging rate in response to cocaine treatment. Cocaine also increased reflexive proboscis extension to sucrose, and sting extension to electric shock. Both of these simple reflexes are modulated by biogenic amines. This shows that systemic cocaine treatment alters behavioural responses that are modulated by biogenic amines in insects. Since insect reward responses involve both octopamine and dopamine signalling, we conclude that cocaine treatment altered diverse reward-related aspects of behaviour in bees. We discuss the implications of these results for understanding the ecology of cocaine as a plant defence compound. Our findings further validate the honey bee as a model system for understanding the behavioural impacts of cocaine, and potentially other drugs of abuse.
Browne, J L; Chan, A Y C
Regular mammography facilitates early detection of breast cancer, and thus increases the chances of survival from this disease. Daughter-initiated (i.e. upward) communication about mammography within mother-daughter dyads may promote mammography to women of screening age. The current study examined this communication behaviour within the context of the Theory of Planned Behaviour (TPB), and aimed to bridge the intention-behaviour gap by trialling an implementation intention (II) intervention that aimed to facilitate upward family communication about mammography. Young women aged 18-39 (N=116) were assigned to either a control or experimental condition, and the latter group formed IIs about initiating a conversation with an older female family member about mammography. Overall, those who formed IIs were more likely to engage in the target communication behaviour, however the intervention was most effective for those who reported low levels of intention at baseline. Perceived behavioural control emerged as the most important variable in predicting the target behaviour. The altruistic nature of this behaviour, and the fact that it is not wholly under volitional control, may have contributed to this finding. Future studies that systematically explore the relative roles of intention and perceived behavioural control in behaviours of this nature are warranted. PMID:21981385
Full Text Available An important aspect of the hunting strategy of neotropical social wasps (Hymenoptera: Vespidae is where they hunt. Three species used two behavioural components in their selection of a place to search for prey. The wasps uti lizcd the odour of freshly damaged leaves as cues (which could be synomones to select which leaves to inspect and also they remembered a place to which they were strongly attracted to hunt recently and returned there. Polybia ignobilis (Haliday, 1836 and Polistes satan Bequaert, 1940 hunted on a lawn of Digitaria diversinervis Stapf immediately after it was mown in significantly larger numbers than at other times. P. ignobilis and Polistes versicolor (Olivier, 1791 hunted in significantly greater numbers on freshly cut leaves of passion vine (Passiflora edulis Sims than on uncut leaves. Sometimes wasps inspected cards rubbed with freshly crushed leaves of P. edulis, but not control cards. Preliminary data suggest that several other species of social wasps around Brasilia hunt in a similar manner on native and exotic plants. Apparently the production of ephemeral odours by freshly cut leaves attract generalist insectivorous predators which perceive these scents and the social wasps investigated are members of the third trophic level of the plants' defence against attacks by herbivores. Available information suggests a difference between the behaviour of generalists and that of specialist arthropod predators which arc attracted to the odour emitted after their particular prey have damaged the leaves.
While nonspecific mechanisms such as activity of NK-cells and induction of interferon were not suppressed after inhomogenous total body irradiation of mice with 1,95/3,90 and 5,85 Gy, an extreme decrease in spleen weight, in the yield of lymphocytes from the spleen and their response to mitogenic stimulation was observed. The general effect of these influences on the interaction of the numerous factors and mechanisms of the nonspecific part of defence was investigated in an antigen-challenge model with stomatitis vesicularis virus in babymice after total body irradiation (3,90 Gy) of the babymice or their pregnant mothers. Irradiation of the babymice showed no significant influence on mortality after infection, while irradiation of their pregnant mothers caused an astonishing decrease of mortality compared to that of animals with no exposure to X-rays. In the same model it was demonstrated that the protective effect of the paramunity inducer 'PIND ORF' on mortality after infection was impaired neither by irradiation of the babymice nor by irradiating their pregnant mothers. The antigen-challenge model Aujeszky virus/adult mouse (exposure to 1,95/3,90 and 5,85 Gy) proved that the influence of irradiation not only depends on the dose but also on the moment of the exposure. The behaviour of opportunistic germs (P. multocida, Ps. aeruginosa) and vaccination viruses (Vaccinia virus, strain Elstree and MVA) in mice remained unchanged after irradiation with 1,95/3,90 Gy, whereas irradiation with 5,85 Gy caused a varying increase of mortality after infection with P. multocida and Ps. aeruginosa. (orig./MG) With 5 refs., 11 tabs
Frei dit Frey, Nicolas
Background Mitogen-activated protein kinases (MAPKs) are key regulators of immune responses in animals and plants. In Arabidopsis, perception of microbe-associated molecular patterns (MAMPs) activates the MAPKs MPK3, MPK4 and MPK6. Increasing information depicts the molecular events activated by MAMPs in plants, but the specific and cooperative contributions of the MAPKs in these signalling events are largely unclear. Results In this work, we analyse the behaviour of MPK3, MPK4 and MPK6 mutants in early and late immune responses triggered by the MAMP flg22 from bacterial flagellin. A genome-wide transcriptome analysis reveals that 36% of the flg22-upregulated genes and 68% of the flg22-downregulated genes are affected in at least one MAPK mutant. So far MPK4 was considered as a negative regulator of immunity, whereas MPK3 and MPK6 were believed to play partially redundant positive functions in defence. Our work reveals that MPK4 is required for the regulation of approximately 50% of flg22-induced genes and we identify a negative role for MPK3 in regulating defence gene expression, flg22-induced salicylic acid accumulation and disease resistance to Pseudomonas syringae. Among the MAPK-dependent genes, 27% of flg22-upregulated genes and 76% of flg22-downregulated genes require two or three MAPKs for their regulation. The flg22-induced MAPK activities are differentially regulated in MPK3 and MPK6 mutants, both in amplitude and duration, revealing a highly interdependent network. Conclusions These data reveal a new set of distinct functions for MPK3, MPK4 and MPK6 and indicate that the plant immune signalling network is choreographed through the interplay of these three interwoven MAPK pathways.
郑显亮; 张婷; 袁浅香
目的:考察自尊、通情与网络利他行为之间的关系.方法:采用大学生网络利他行为量表、自尊量表和梅拉比安特质通情量表对587名大学生进行调查.结果:①大学生网络利他行为存在显著的性别差异,男生网络利他程度显著高于女生;②大学生网络利他行为、自尊和通情间均存在显著正相关;③分层回归分析结果表明,自尊和通情均能显著预测大学生网络利他行为,通情在自尊与大学生网络利他行为关系间起部分中介作用.结论:自尊可以直接影响大学生网络利他行为,同时又通过通情的中介作用对大学生网络利他行为产生间接影响.%Objective: To investigate the relationships of self-esteem, empathy and college students' internet altruistic behavior. Methods: 587 college students were investigated by Internet Altruistic Behavior Scale of Undergraduates, Self-esteem Scale and Mehrabian' Strait Empathy Scale. Results: ①College students' internet altruistic behavior showed significant gender difference; boys' score was significantly higher than that of girls. ②There were significant positive correlations among self-esteem, empathy and internet altruistic behavior. ③The results of layered regression showed that serf-esteem and empathy could significantly predict internet altruistic behavior. The effect of self-esteem on internet altruistic behavior was partially mediated by empathy. Conclusion: Self-esteem can directly affect college students' internet altruistic behavior, and also indirectly influence it through empathy.
Using cooperation in chimpanzees as a case study, this article argues that research on animal minds needs to steer a course between 'association-blindness'--the failure to consider associative learning as a candidate explanation for complex behaviour--and 'simple-mindedness'--the assumption that associative explanations trump more cognitive hypotheses. Association-blindness is challenged by the evidence that associative learning occurs in a wide range of taxa and functional contexts, and is a major force guiding the development of complex human behaviour. Furthermore, contrary to a common view, association-blindness is not entailed by the rejection of behaviourism. Simple-mindedness is founded on Morgan's canon, a methodological principle recommending 'lower' over 'higher' explanations for animal behaviour. Studies in the history and philosophy of science show that Morgan failed to offer an adequate justification for his canon, and subsequent attempts to justify the canon using evolutionary arguments and appeals to simplicity have not been successful. The weaknesses of association-blindness and simple-mindedness imply that there are no short-cuts to finding out about animal minds. To decide between associative and yet more cognitive explanations for animal behaviour, we have to spell them out in sufficient detail to allow differential predictions, and to test these predictions through observation and experiment. PMID:22927568
G. S. Mukherjee
Full Text Available Three words ‘Moseley, Soldier & Science’ in which the last two are so deeply associated with the name of the English scientist Moseley that these have become virtually synonyms of Moseley in the context of remembrance of the professional contribution and character of the unique soldier-scientist Moseley because these two words are very special for him in the sense that they often are essential to understand the personality of iconic Moseley. His keen interest in the service of Science as researcher and on the other hand, his involvement in the Defence services as soldier is really unique example of personification of total commitment to the cause of defence of his country and his deep dedication for the cause of unfolding the scientific truth towards building up a way forward to enrich human history. Moseley’s dual personalities as a scientist and as a soldier rest on the framework of Science & Defence in which the ideas and appeal of Science is universal whereas the ideals of a soldier in Defence is purely national and personal; and that was manifested in his attitude and approach - so intimate and so intense that it would not be inappropriate to say that ‘Service to Science’ and ‘Service to Defence’ for this real world, as Moseley exemplified were in a way virtually two sides of the same coin. Thus, Moseley is truly a composite personality which can be understood from his passion for Science as essentially meant for global cause but his zeal as soldier for Defence was pristine and core to his heart. In fact, often such deeply motivated men contribute for creation of history of this real composite world.Defence Science Journal, 2013, 63(4, pp.343-345, DOI:http://dx.doi.org/10.14429/dsj.63.4873
David W. Archer
Full Text Available Information about cyberthreats within networks spreads slowly relative to the speed at which those threats spread. Typical "threat feeds" that are commercially available also disseminate information slowly relative to the propagation speed of attacks, and they often convey irrelevant information about imminent threats. As a result, hosts sharing a network may miss opportunities to improve their defence postures against imminent attack because needed information arrives too late or is lost in irrelevant noise. We envision timely, relevant peer-to-peer sharing of threat information – based on current technologies – as a solution to these problems and as a useful design pattern for defensive cyberwarfare. In our setting, network nodes form communities that we call enclaves, where each node defends itself while sharing information on imminent threats with peers that have similar threat exposure. In this article, we present our vision for this solution. We sketch the architecture of a typical node in such a network and how it might interact with a framework for sharing threat information; we explain why certain defensive countermeasures may work better in our setting; we discuss current tools that could be used as components in our vision; and we describe opportunities for future research and development.
Woodward, Ruth M.
The terahertz (1 THz = 1012 Hz, 3 mm or 33 cm-1) region of the electromagnetic spectrum is typically defined in the frequency range 100 GHz to 10 THz, corresponding to a wavelength range of 3 mm to 30 microns. Owing to a lack of suitable coherent sources and detectors, this region has only been investigated in earnest in the last ten years for terrestrial imaging and spectroscopy applications. Its role in the medical, pharmaceutical, non-destructive testing and more recently security industries is now being examined. The terahertz frequency range is of particular interest since it is able to probe several molecular interactions including the intermolecular vibrations, large amplitude vibrations and twisting and torsional modes. Molecules have also shown polarization sensitivity to the incident terahertz radiation. The ability of terahertz radiation to investigate conformational change makes it an important part of the electromagnetic spectrum. Terahertz radiation has the potential to provide additional information, which may complement other optically based sensing technologies. The use of terahertz technology in the security and defence industry is discussed, with a specific focus on biological and chemical sensing. The challenges faced in bringing terahertz technology into the market place will be discussed.
Full Text Available Sea-skim~ing cruise missiles pose the greatest threat to a surface ship in the present-day war scenario. The convenitional close-in-weapon-systems (CIWSs are becoming less reliable against these new challenges requiring extremely fast reaction time. Naval Forces see a high energy laser as a feasible andjeffective directed energy weapon against sea-skimming antiship cruise missiles becauseof its .ability to deliver destructive energy at the speed of light on to a distant target. The paper comparesthe technology and capability of deuterium fluoride (DF and chemical-oxygen-iodine laser (COIL in effectively performing the role of a shipborne CIWS altainst sea-skimming missiles. Out of these twolasers, it is argued that DF laser wo.uld be more effective a,s a shipborne weapon for defence against sea-skimmin,g cruise missiles. Besides the high energy laser as the primary (killing laser, othersub-systems required in the complete weapon system would be: A beacon laser to sense phase distor'ions in the primary laser, adaptive optics to compensate the atmospheric distortions, beam-directing optics, illuminating lasers, IRST sensors, surveillance and tracking radars, interfacing system, etc.
Ben-Yosef, Michael; Pasternak, Zohar; Jurkevitch, Edouard; Yuval, Boaz
Ripe fruit offer readily available nutrients for many animals, including fruit fly larvae (Diptera: Tephritidae) and their associated rot-inducing bacteria. Yet, during most of their ontogeny, fruit remain chemically defended and effectively suppress herbivores and pathogens by high levels of secondary metabolites. Olive flies (Bactrocera oleae) are uniquely able to develop in unripe olives. Unlike other frugivorous tephritids, the larvae maintain bacteria confined within their midgut caeca. We examined the interaction between larvae, their associated bacteria, and fruit chemical defence, hypothesizing that bacterial contribution to larval development is contingent on the phenology of fruit defensive chemistry. We demonstrate that larvae require their natural complement of bacteria (Candidatus Erwinia dacicola: Enterobacteriaceae) in order to develop in unripe olives. Conversely, when feeding on ripe fruit, larval development proceeds independently of these bacteria. Our experiments suggest that bacteria counteract the inhibitory effect of oleuropein-the principal phenolic glycoside in unripe olives. In light of these results, we suggest that the unique symbiosis in olive flies, compared with other frugivorous tephritids, is understood by considering the relationship between the fly, bacteria and fruit chemistry. When applied in an evolutionary context, this approach may also point out the forces which shaped symbioses across the Tephritidae. PMID:26587275
Wiesel, Lea; Davis, Jayne L; Milne, Linda; Redondo Fernandez, Vanesa; Herold, Miriam B; Middlefell Williams, Jill; Morris, Jenny; Hedley, Pete E; Harrower, Brian; Newton, Adrian C; Birch, Paul R J; Gilroy, Eleanor M; Hein, Ingo
Phytohormones are involved in diverse aspects of plant life including the regulation of plant growth, development and reproduction, as well as governing biotic and abiotic stress responses. We have generated a comprehensive transcriptional reference map of the early potato responses to exogenous application of the defence hormones abscisic acid, brassinolides (applied as epibrassinolide), ethylene (applied as the ethylene precursor aminocyclopropanecarboxylic acid), salicylic acid and jasmonic acid (applied as methyl jasmonate). Of the 39000 predicted genes on the microarray, a total of 2677 and 2473 genes were significantly differentially expressed at 1 h and 6 h after hormone treatment, respectively. Specific marker genes newly identified for the early hormone responses in potato include: a homeodomain 20 transcription factor (DMG400000248) for abscisic acid; a SAUR gene (DMG400016561) induced in epibrassinolide treated plants; an osmotin gene (DMG400003057) specifically enhanced by aminocyclopropanecarboxylic acid; a gene weakly similar to AtWRKY40 (DMG402007388) that was induced by salicylic acid; and a jasmonate ZIM-domain protein 1 (DMG400002930) which was specifically activated by methyl jasmonate. An online database has been set up to query the expression patterns of potato genes represented on the microarray that can also incorporate future microarray or RNAseq-based expression studies. PMID:26477733
Rodrigo Ferrada Stoehrel
Full Text Available In recent years, the Swedish Armed Forces have produced and distributed highly edited video clips on YouTube that show moving images of military activity. Alongside this development, mobile phone apps have emerged as an important channel through which the user can experience and take an interactive part in the staging of contemporary armed conflict. This article examines the way in which the aesthetic and affective experience of Swedish defence and security policy is socially and (media-culturally (co-constructed and how the official representation of Swedish military intervention (reproduces political and economic effects when these activities are distributed through traditional and social media such as YouTube and digital apps. Based on Isabela and Norman Fairclough’s thoughts on political discourse, Michel Foucault’s dialectic idea of power/knowledge, and Sara Ahmed’s concept of the affective, I discuss how the Swedish digital military aesthetic is part of a broader political and economic practice which has consequences beyond the digital, the semiotic and what might at first glance appear to be pure entertainment.
In this paper, I apply the concept of psychic skin to analytic work with people suffering from personality disorders and psychoses. When psychoses emerge, the defensive skin which protects the ego is breached and violent unconscious forces rip through the personality. Some of the patients diagnosed as schizophrenic with whom I work have identified with archetypal characters such as Christ, Satan, John Lennon and the Queen. I attempt to show how the adoption of these inflated personas can serve as secondary psychic skins. Such delusional identifications can provide a protective shield to hide the denuded self and prevent intrusion from the external world. Through clinical example, I try to demonstrate how these archetypal 'second skins' can preserve life until internal and external conditions make it possible for the self to emerge. I contrast such psychotic identifications with 'thin-skinned' and 'thick-skinned' narcissism as well as 'defences of the self' in borderline states where the psychic skin may be damaged but does not disintegrate. I also look at the ways in which Jung's own personal experience was different from this and how he managed to avert psychotic breakdown. PMID:22288539
The aim of the present study is to review current and future scientific trends in radiation protection and civil defence of the nuclear research center of the Atomic Energy Authority of Egypt. The main areas of interest are summarized as follows: 1. Organization and training: Up dating radiation protection legislation. Information transfer via translation to Arabic of latest IAEA and ICRP publications. Establishing data base for rad port services in egypt. Updating radiation protection training programmes, and application of decision-aiding techniques in radiation protection (justification and optimization). 2. Occupational radiation control: Mixed field external personnel dosimetry/detection. internal dosimetry/biophysics/W B counter / Bioassay. Area monitoring and surface, and updating radiation format. 3. Public radiation control: Environmental programme around inshass reactor. Transport of radioactive material. Transfer of radioactivity in aquatic environments. storage of radioactive waste, and annual exposure to members of the public-natural radiation, medical others. 4. Emergency: First aids decontamination, decontamination of personnel and equipment, dose calculation after accidents, and Handling radiation accidents/emergency planning. 5. Quality assurance: Calibration of radiation sources and measuring devices, and intercomparison personnel dosimetry programme. The proposed plan can be completed within 1992-1997 national plan with the support of IAEA technical assistance, research contract and proper funding from the atomic energy authority of egypt
van der Meer, Jos W M; Joosten, Leo A B; Riksen, Niels; Netea, Mihai G
The innate arm of the immune system is generally viewed as primitive and non-specific and - in contrast to the adaptive immune arm - not to possess memory. However in plants and invertebrate animals that lack adaptive immunity, innate immunity will exhibit a prolonged enhanced functional state after adequate priming. A similar enhancement of function of the innate immunity has occasionally been described in vertebrates, including humans. Over the past few years we have studied this phenomenon in greater detail and we have coined the term 'Trained (innate) immunity' (TI). TI can be induced by a variety of stimuli, of which we have studied BCG and β-glucan in greater detail. The non-specific protective effects of BCG that have been observed in vaccination studies in the literature are probably due to TI. Monocytes and macrophages are among the main cells of the innate immune arm that can be trained. We have discovered that both BCG (via NOD2 signalling) and β-glucan (via dectin-1) induce epigenetic reprogramming, in particular stable changes in histone trimethylation at H3K4. These epigenetic changes lead to cellular activation, enhanced cytokine production and a change in the metabolic state of the cell with a shift from oxidative phosphorylation to aerobic glycolysis. TI is not only important for host defence and vaccine responses, but most probably also for diseases like atherosclerosis. Modulation of TI is a promising area for new treatments. PMID:26597205
Full Text Available In recent times the SA Defence Force (SADF has been bombarded with a variety of methods and approaches to the improvement of productivity, financial savings and, most recently, for quality of work life or quality assurance. Various approaches have included the concepts of Total Quality Management (TQM, Quality Circles (and variants in the guise of Triads and others, Methodology, Unit Management Systems, Cost Control Systems, Deterministic Productivity Accounting and the Iike. There have been many benefits to be found in these various approaches, each of which concentrates on certain aspects of productivity. That there have been great achievements in productivity in the SADF is a matter of record, a record which is reflected in a National Award for Productivity, a smaller more efficient SADF, and a reputation for submitting more recommendations for improvements than other departments in the Public Service. At a more personal level though, the writer has gained the impression that no or very little attempt has been made to integrate selected aspects of these approaches into an overall "productivity” strategy acceptable to the SADF. That there is a need for such an overall strategy is clear from the sentiments expressed recently by the members of the SADF's Productivity Co-ordination Committee when attempting to indicate the way ahead to even greater productivity in the SADF (Meeting, January 1991. In this paper a strategy for the improvement of productivity and the quality of work life which is acceptable to the SADF is proposed.
Zvonko Biljecki; Goran Gugić; Aida Osmanagić; Stipica Pavičić; Mladen Rapaić; Petra Sajko; Tomislav Tonković; Daniel Vencler; Željko Železnjak
One of the goals that Partnership for Peace has set, within domain of geospatial information, is the implementation of a military geoinformation system. Besides this important strategic objective for the Republic of Croatia, the military geoinformation system will enhance activities of the Ministry of Defence and Armed Forces and in such way improve national defence and cooperation with NATO members and members of the Partnership for Peace. This paper describes overall system principles based...
Dostálek, Tomáš; Rokaya, Maan Bahadur; Maršík, Petr; Rezek, Jan; Skuhrovec, Jiří; Pavela, Roman; Münzbergová, Zuzana
The type and intensity of plant-herbivore interactions are likely to be altered under climate change as a consequence of differential dispersal rates of plants and their herbivores. Here, we studied variation in herbivore damage on Salvia nubicola in the field and compared its growth and defence strategies against herbivores in controlled conditions using seeds from populations along a broad altitudinal gradient. Our work is one of the first studies to simultaneously measure complex intraspecific variation in plant growth, direct and indirect defences as well as plant tolerance (ability to regrow) as a consequence of herbivore attack simulated by clipping. In the field, we found that plants experienced higher herbivore pressure in lower altitudes. In the greenhouse, plants grown from seeds collected in lower-altitude populations grew better and produced a higher content of phenolic compounds (direct defence) and volatile organic compounds (indirect defence) in response to simulated herbivory. However, there were no differences in tolerance and effect of S. nubicola extracts on the model generalist herbivore Spodoptera littoralis (direct defence) along the altitudinal gradient. Although we found that S. nubicola developed a range of defence strategies, the strategies do not seem to be used simultaneously in all populations even though most of them are correlated with altitudinal gradient. Our finding is in agreement with the current knowledge that co-expression of multiple defences might be costly for a plant, since investment in defensive traits is assumed to reduce the resource availability for growth and reproduction. Our study thus shows the importance of simultaneous study of different defence strategies since understanding these trade-offs could be necessary for detecting the mechanisms by which plants are able to cope with future climate change. PMID:27169609
The training environment of the Irish Defence Forces: integrated training and bullying in the workplace In this chapter I will refer to recruit and cadet training within the defence forces in light of international trends in integrated training. Following the consideration of ‘commitment’ in terms of numbers of women recruited to the organisation in chapter five, this chapter assesses the “education” component of the setting (Reskin and Padavic, 1994). Through an examination of archival dat...
Claudia ANDRITOI; Florentina LUPSA
Between the right to defence and assistance and the civil rights a close connection has been identified. Sometimes the realisation and protection of these rights, such as the right to life, to personal dignity, to private life etc., in general are impossible without the right to defence and legal assistance. First, the right to legal assistance allows the individual to comprehend the powers conferred to him by this right. Second, the right to legal assistance allows the protection and enforce...
Vallin, Adrian; Jakobsson, Sven; Lind, Johan; Wiklund, Christer
Long-lived butterflies that hibernate as adults are expected to have well-developed antipredation devices as a result of their long exposure to natural enemies. The peacock butterfly, Inachis io, for instance, is a cryptic leaf mimic when resting, but shifts to active defence when disturbed, performing a repeated sequence of movements exposing major eyespots on the wings accompanied by a hissing noise. We studied the effect of visual and auditory defence by staging experiments in which wild-c...
Dutertre, Sébastien; Jin, Ai-Hua; Vetter, Irina; Hamilton, Brett; Sunagar, Kartik; Lavergne, Vincent; Dutertre, Valentin; Fry, Bryan G.; Antunes, Agostinho; Venter, Deon J.; Alewood, Paul F.; Lewis, Richard J.
Venomous animals are thought to inject the same combination of toxins for both predation and defence, presumably exploiting conserved target pharmacology across prey and predators. Remarkably, cone snails can rapidly switch between distinct venoms in response to predatory or defensive stimuli. Here, we show that the defence-evoked venom of Conus geographus contains high levels of paralytic toxins that potently block neuromuscular receptors, consistent with its lethal effects on humans. In con...
The innate immunity is the first line defence against invading pathogens, such as the facultative intracellular, Gram-negative bacterium Legionella pneumophila. It senses microorganisms by so-called pattern recognition receptors, e.g. Toll-like receptors (TLRs), and initiates subsequent defence mechanisms. Recent studies indicated an important role of type I interferons in bacterial infections. Moreover, genetic studies in different mice strains demonstrated that different alleles of the Nod-...
Dostálek, Tomáš; Rokaya, Maan Bahadur; Maršík, Petr; Rezek, Jan; Skuhrovec, Jiří; Pavela, Roman; Münzbergová, Zuzana
The type and intensity of plant–herbivore interactions are likely to be altered under climate change as a consequence of differential dispersal rates of plants and their herbivores. Here, we studied variation in herbivore damage on Salvia nubicola in the field and compared its growth and defence strategies against herbivores in controlled conditions using seeds from populations along a broad altitudinal gradient. Our work is one of the first studies to simultaneously measure complex intraspecific variation in plant growth, direct and indirect defences as well as plant tolerance (ability to regrow) as a consequence of herbivore attack simulated by clipping. In the field, we found that plants experienced higher herbivore pressure in lower altitudes. In the greenhouse, plants grown from seeds collected in lower-altitude populations grew better and produced a higher content of phenolic compounds (direct defence) and volatile organic compounds (indirect defence) in response to simulated herbivory. However, there were no differences in tolerance and effect of S. nubicola extracts on the model generalist herbivore Spodoptera littoralis (direct defence) along the altitudinal gradient. Although we found that S. nubicola developed a range of defence strategies, the strategies do not seem to be used simultaneously in all populations even though most of them are correlated with altitudinal gradient. Our finding is in agreement with the current knowledge that co-expression of multiple defences might be costly for a plant, since investment in defensive traits is assumed to reduce the resource availability for growth and reproduction. Our study thus shows the importance of simultaneous study of different defence strategies since understanding these trade-offs could be necessary for detecting the mechanisms by which plants are able to cope with future climate change. PMID:27169609
Paul Dunne; Richard Haines
In post-Apartheid South Africa, the ANC Government faced the challenge of restructuring an unsustainably large defence sector. This was in the context of economic and social problems and a declining international arms market. This paper considers the restructuring of the South African industry over that period and more recently, providing a valuable case study of defence industrial restructuring in a small industrialised economy. It considers how the public sector (DENEL) and private sector r...
Bardin, Marc; Comby, Morgane; Lenaerts, Ruben; Nicot, Philippe
The development of plant defence stimulants to increase host resistance represents anattractive alternative to fungicides for the protection of crops against plant pathogens. In this study we evaluated the efficiency of 14 products presumed to induce plant defence mechanisms against Botrytis cinerea on tomato and lettuce. Two days after the application of the products, tomato and lettuce leaves were inoculated with B. cinerea and incubated in conditions conducive to disease development.Out...
Full Text Available This article presents preliminary findings on current environmental management practices used by the South African National Defence Force (SANDF at the Grahamstown Military Installation (GMI. These findings comprise interviews with SANDF officials and an analysis of official documents, which include the first and second editions of the Environmental Management Plan for Defence (2001 & 2008 respectively. The study on which this article reports, found that the emphasis placed on environmental protection within defence force activities worldwide has compelled the South African Department of Defence and Military Veterans (SA DODMV to regulate the management of the environment within its properties. Yet, these efforts have faced numerous challenges that range from financial to human resources deficiencies. Consequently, the military installation at Grahamstown does not have environmentally knowledgeable and qualified personnel to deal with environmental issues. From the analysis of official documents as well as interviews with respondents, it was established that the SA DODMV itself does not have a budget for environmental services. The combination of all these drawbacks has led to the failure of the implementation of the Environmental Management System (EMS for Defence at this military installation (i.e. GMI of the SANDF. Undoubtedly, all these challenges have severely compromised the commitment of the SA DODMV to honour its environmental management obligations. Moreover, the deficiencies of all these resources undermine the sustainable utilisation of these national assets (natural resources entrusted to the defence force. The study reported here proposes an ideal model for the successful implementation of the EMS in SANDF military installations.
Fones, Helen N; Eyles, Chris J; Bennett, Mark H; Smith, J Andrew C; Preston, Gail M
The metal hyperaccumulator plant Noccaea caerulescens is protected from disease by the accumulation of high concentrations of metals in its aerial tissues, which are toxic to many pathogens. As these metals can lead to the production of damaging reactive oxygen species (ROS), metal hyperaccumulator plants have developed highly effective ROS tolerance mechanisms, which might quench ROS-based signals. We therefore investigated whether metal accumulation alters defence signalling via ROS in this plant. We studied the effect of zinc (Zn) accumulation by N. caerulescens on pathogen-induced ROS production, salicylic acid accumulation and downstream defence responses, such as callose deposition and pathogenesis-related (PR) gene expression, to the bacterial pathogen Pseudomonas syringae pv. maculicola. The accumulation of Zn caused increased superoxide production in N. caerulescens, but inoculation with P. syringae did not elicit the defensive oxidative burst typical of most plants. Defences dependent on signalling through ROS (callose and PR gene expression) were also modified or absent in N. caerulescens, whereas salicylic acid production in response to infection was retained. These observations suggest that metal hyperaccumulation is incompatible with defence signalling through ROS and that, as metal hyperaccumulation became effective as a form of elemental defence, normal defence responses became progressively uncoupled from ROS signalling in N. caerulescens. PMID:23758201
One of the most dangerous forms of terrorism is nuclear and radiological terrorism, including threats by terrorists to use so called dirty bombs. The Russian Federation?s national security concept recognizes the possibility of a terrorist threat arising in practically any sphere of State activity. The threat of nuclear or radiological terrorism is considered an integral part in the overall problem of ensuring national security. Without doubt, reliable physical protection of nuclear material and a reliable system of accounting for and control of nuclear material and radioactive substances play a key role in preventing and countering possible acts of nuclear and radiological terrorism. Clearly, however, the problem of combating the manifestations of nuclear and radiological terrorism cannot be solved by physical protection measures alone. Considering that the whole threat of nuclear and radiological terrorism is conditional upon the possibility of illicit trafficking in nuclear material and radioactive substances and their illegal possession or transport in a State?s territory, across its customs boundaries or in transit across its territory, national systems for responding to the threat of terrorism must be designed as an informational and logical whole integrated with the system for combating illicit trafficking in nuclear material and radioactive substances. Generally speaking, the term ?second line of defence? refers to the set of measures to combat illicit trafficking in nuclear material and radioactive substances at the next level above the nuclear facility. This level can be the territory of a country or its border. The ?second line of defence and countermeasures against nuclear and radiological terrorism? means coordinated actions taken by federal bodies of the executive power whose functional duties include the prevention of terrorist acts in general, and by law enforcement bodies, ministries, departments and organizations directly concerned with the use of
Van Rooijen Nico
Full Text Available Abstract Background Mice with genetic deficiencies in adaptive immunity are used for the grafting of human cells or pathogens, to study human diseases, however, the innate immune responses to xenografts in these mice has received little attention. Using the NOD/SCID Plasmodium falciparum mouse model an analysis of innate defences responsible for the substantial control of P. falciparum which remains in such mice, was performed. Methods NOD/SCID mice undergoing an immunomodulatory protocol that includes, clodronate-loaded liposomes to deplete macrophages and an anti-polymorphonuclear leukocytes antibody, were grafted with human red blood cells and P. falciparum. The systematic and kinetic analysis of the remaining innate immune responses included the number and phenotype of peripheral blood leukocytes as well as inflammatory cytokines/chemokines released in periphery. The innate responses towards the murine parasite Plasmodium yoelii were used as a control. Results Results show that 1 P. falciparum induces a strong inflammation characterized by an increase in circulating leukocytes and the release of inflammatory cytokines; 2 in contrast, the rodent parasite P. yoelii, induces a far more moderate inflammation; 3 human red blood cells and the anti-inflammatory agents employed induce low-grade inflammation; and 4 macrophages seem to bear the most critical function in controlling P. falciparum survival in those mice, whereas polymorphonuclear and NK cells have only a minor role. Conclusions Despite the use of an immunomodulatory treatment, immunodeficient NOD/SCID mice are still able to mount substantial innate responses that seem to be correlated with parasite clearance. Those results bring new insights on the ability of innate immunity from immunodeficient mice to control xenografts of cells of human origin and human pathogens.
Probably the oldest and most widespread antimicrobial strategy in living organisms is the use of antimicrobial peptides. Bacteria secrete such defence peptides, termed bacteriocins, that they use for microbial competitions. Microcins are bacteriocins of less than 10 kDa produced by Escherichia coli and related enterobacteria through the ribosomal pathway. They are synthesized as linear precursors, which can further undergo complex post-translational modifications resulting from dedicated maturation enzymes encoded in the microcin gene clusters, and are processed by proteolytic cleavage. Microcins exert potent bactericidal activities that use subtle and clever mechanisms to cross outer and inner membranes of Gram-negative bacteria. To cross the outer membrane, siderophore-microcins hijack receptors involved in iron acquisition. The lasso-peptide microcin J25, which is characterized by a knotted arrangement where the C-terminal tail is threaded through an N-terminal macrolactam ring, uses a hydroxamate siderophore receptor and the inner-membrane protein SbmA for import in sensitive bacteria, where it inhibits bacterial transcription through binding to RNAP (RNA polymerase). Microcin C produced as a heptapeptide adenylate, requires an outer-membrane porin and an inner-membrane ABC (ATP-binding-cassette) transporter to reach the cytoplasm of target bacteria, where it is processed by proteases into a non-hydrolysable aspartyl-adenylate analogue. Therefore, despite showing different killing mechanisms and the absence of any structural homology, microcins have the common characteristic to use Trojan horse strategies to destroy their competitors. They offer new and promising tracks for further design and engineering of novel efficient antibiotics. PMID:23176498
Y. S. Rajan
Full Text Available The design of a suitable system for image data processing, analysis and applications in Defence is governed by users' requirements during peace time and prehostility/hostility period. The users need timely information and image products for decision-making. The product specifications in terms of their scale, geometrical accuracy, information content, and turnaround time among other things are crucial for the design of systems. The systems are not complete without efficient software for information extraction and analysis and for aiding decision-making process. Usually, the base data is from high resolution remote sensing systems, both airborne and spaceborne, and also from conventional sources, like topomap and other intelligence gathering mechanisms. The database thus evolved is basic and vital for a decision support system. The sensors providing input to the database creation could be airborne high resolution camera systems, high resolution synthetic aperture radar systems and thermal imaging systems operating from a stand-off range of 50 to 100 km, or from high resolution spaceborne panchromatic optical and synthetic aperture radar imagery. High resolution stereo data from airborne and spaceborne sensors are also increasingly needed for image interpretation and analysis. The digital elevation data is another important information, derived from either existing topographic maps or high resolution space stereo imagery. The system also should cater to a large information archival/retrieval system and data dissimination system for the users spread far and wide. This may call for to and fro traffic between central operational system and units spread over different locations, preferably, through high speed satellite communication channels. Finally, the total system should have reliability, data security, adequate redundancy, user-friendliness and be efficient enough to provide timely information transfer for the decision makers. This paper discusses
Full Text Available Eales′ disease (ED is an idiopathic retinal periphlebitis characterized by capillary non-perfusion and neovascularization. In addition to the existing system, a new staging system has been proposed by Saxena et al . Immunological, molecular biological and biochemical studies have indicated the role of human leucocyte antigen, retinal S antigen autoimmunity, Mycobacterium tuberculosis genome, free radical damage and possibly hyperhomocysteinemia in its etiopathogenesis, which appears multifactorial. Oxidant stress has been shown by increase in the levels of thiobarbituric acid reactive substances (lipid oxidation in the vitreous, erythrocytes, platelets, and monocytes. A decrease in vitamins E and C both in active and healed vasculitis, superoxide dismutase, glutathione, and glutathione peroxidase showed a weakened antioxidant defence. Epiretinal membrane from patients of ED who underwent surgery showed, by immunolocalization, presence of carboxy methyl lysine, an advanced glycation end product formed by glycoxidation and is involved in angiogenesis. OH· free radical accumulation in monocytes has been directly shown by electron spin resonance spectrometry. Free radical damage to DNA and of protein was shown by the accumulation of 8 hydroxy 2 deoxyguanosine (in leucocytes and nitrotyrosine (in monocytes, respectively. Nitrosative stress was shown by increased expression of inducible nitric oxide synthase in monocytes in which levels of iron and copper were increased while those of zinc decreased. A novel 88 kDa protein was found in serum and vitreous in inflammatory condition and had antioxidant function. Platelet fluidity was also affected. Oral, methotrexate in low dosage (12.5 mg/week for 12 weeks as well as oral vitamin E (400 IU and C (500 mg daily for 8 weeks are reported to have beneficial effects.
Full Text Available This article revisits some of the main arguments presented (in the South African context since the late 1990s in relation to the regional security demands placed on the South African National Defence Force (SANDF on the one hand, and the configuration of the force design imposed on the SANDF on the other. These issues are of great relevance to the South African Department of Defence’s recent (2012 official pronouncements and related defence thinking on the current and future external role of the South African military, specifically with regard to post-conflict reconstruction and development. The aim of the article is to examine the dynamics of recent years – philosophical and practical – that gave rise to the policy “move” or “shift” from defence in a democracy (1998 to defence, security and development (2012.[i] In addition, the article aims to analyse and discuss the new comprehensive guidelines for defence force design in the Draft Defence Review 2012 and reflects on some of the most important policy implications for the SANDF in this regard – specifically given the demands placed on the SANDF in the field of post-conflict reconstruction and development. The author contends that the Department of Defence has now gained a clearer idea or perspective of what the future role(s of the South African military should be through the assessment of its function, principles and goals expounded in the Draft Defence Review 2012. [i] At the time of writing it was planned to replace the Defence Review 1998, which was published under the theme of Defence in a democracy, with a new Defence Review 2012, to be published under the theme Defence, security, development.
Oluwafemi, Sunday; Dewhirst, Sarah Y.; Veyrat, Nathalie; Powers, Stephen; Bruce, Toby J.A.; Caulfield, John C.; Pickett, John A; Birkett, Michael A.
cis-Jasmone (CJ) is a natural plant product that activates defence against herbivores in model and crop plants. In this study, we investigated whether CJ could prime defence in maize, Zea mays, against the leafhopper, Cicadulina storeyi, responsible for the transmission of maize streak virus (MSV). Priming occurs when a pre-treatment, in this case CJ, increases the potency and speed of a defence response upon subsequent attack on the plant. Here, we tested insect responses to plant volatile o...
Dirk J. Geldenhuys; Madia M. Levin; Annelize van Niekerk
Orientation: This article deals with the unconscious role of risk management in an African country.Research purpose: The aim of the study is to describe how risk management unconsciously influences behaviour when doing business in an African country.Motivation for the study: Operational risk management is a rational management imperative. However, this does not take cognisance of the unconscious role of risk management. A systems-psychodynamic perspective might be particularly relevant if the...
Čížek, Lukáš; Fric, Zdeněk; Konvička, Martin
Roč. 31, č. 4 (2006), s. 337-344. ISSN 0307-6946 R&D Projects: GA AV ČR(CZ) KJB6007306; GA ČR(CZ) GD206/03/H034 Institutional research plan: CEZ:AV0Z50070508 Keywords : butterfly phylogeny * comparative method * herbivory Subject RIV: EH - Ecology, Behaviour Impact factor: 1.960, year: 2006
This book presents a comprehensive treatment of visual analysis of behaviour from computational-modelling and algorithm-design perspectives. This title: covers learning-group activity models, unsupervised behaviour profiling, hierarchical behaviour discovery, learning behavioural context, modelling rare behaviours, and 'man-in-the-loop' active learning; examines multi-camera behaviour correlation, person re-identification, and 'connecting-the-dots' for abnormal behaviour detection; discusses Bayesian information criterion, Bayesian networks, 'bag-of-words' representation, canonical correlation
Gish, Moshe; Mescher, Mark C; De Moraes, Consuelo M
Extrafloral (EF) nectaries recruit carnivorous arthropods that protect plants from herbivory, but they can also be exploited by nectar thieves. We studied the opportunistic, targeted predation (and destruction) of EF nectaries by insects, and the localized chemical defences that plants presumably use to minimize this effect. In field and laboratory experiments, we identified insects that were possibly responsible for EF nectary predation in Vicia faba (fava bean) and determined the extent and accuracy of the feeding damage done to the EF nectaries by these insects. We also performed biochemical analyses of plant tissue samples in order to detect microscale distribution patterns of chemical defences in the area of the EF nectary. We observed selective, targeted feeding on EF nectaries by several insect species, including some that are otherwise not primarily herbivorous. Biochemical analyses revealed high concentrations of l-3,4-dihydroxyphenylalanine, a non-protein amino acid that is toxic to insects, near and within the EF nectaries. These results suggest that plants allocate defences to the protection of EF nectaries from predation, consistent with expectations of optimal defence theory, and that this may not be entirely effective, as insects limit their exposure to these defences by consuming only the secreting tissue of the nectary. PMID:26446809
K. Imroze; N. G. Prasad
Mating has been widely reported to be a costly event for females. Studies indicate that female cost of mating in terms of fecundity and survivorship can be affected by their mates, leading to antagonistic coevolution between the sexes. However, as of now, there is no evidence that the female cost of mating in terms of immune defence is affected by their mates. We assess the effect of different sized males on antibacterial immune defence and reproductive fitness of their mates. We used a large outbred population of Drososphila melanogaster as the host and Serratia marcescens as the pathogen. We generated three different male phenotypes: small, medium and large, by manipulating larval densities. Compared to females mating with small males, those mating with large males had higher bacterial loads and lower fecundity. There was no significant effect of male phenotype on the fraction of females mated or copulation duration (an indicator of ejaculate investment). Thus, our study is the first clear demonstration that male phenotype can affect the cost of mating to females in terms of their antibacterial immune defence. Mating with large males imposes an additional cost of mating to females in terms of reduced immune defence. The observed results are very likely due to qualitative/quantitative differences in the ejaculates of the three different types of males. If the phenotypic variation that we observed in males in our study is mirrored by genetic variation, then, it can potentially lead to antagonistic coevolution of the sexes over immune defence.
Oexle, S; Jansen, M; Pauwels, K; Sommaruga, R; De Meester, L; Stoks, R
Natural populations can cope with rapid changes in stressors by relying on sets of physiological defence mechanisms. Little is known onto what extent these physiological responses reflect plasticity and/or genetic adaptation, evolve in the same direction and result in an increased defence ability. Using resurrection ecology, we studied how a natural Daphnia magna population adjusted its antioxidant defence to ultraviolet radiation (UVR) during a period with increasing incident UVR reaching the water surface. We demonstrate a rapid evolution of the induction patterns of key antioxidant enzymes under UVR exposure in the laboratory. Notably, evolutionary changes strongly differed among enzymes and mainly involved the evolution of UV-induced plasticity. Whereas D. magna evolved a strong plastic up-regulation of glutathione peroxidase under UVR, it evolved a lower plastic up-regulation of glutathione S-transferase and superoxide dismutase and a plastic down-regulation of catalase. The differentially evolved antioxidant strategies were collectively equally effective in dealing with oxidative stress because they resulted in the same high levels of oxidative damage (to lipids, proteins and DNA) and lowered fitness (intrinsic growth rate) under UVR exposure. The lack of better protection against UVR may suggest that the UVR exposure did not increase between both periods. Predator-induced evolution to migrate to lower depths that occurred during the same period may have contributed to the evolved defence strategy. Our results highlight the need for a multiple trait approach when focusing on the evolution of defence mechanisms. PMID:27018861
Satinder K. Brar
Full Text Available The present study was carried out to adjudge the soil quality of two sites at the defence establishments in India. Various soil samples were collected from the surface and up to 20 cm depth (subsurface as per apportioned gridding method. These samples were subjected to air drying for 15 days and were characterised for various parameters. The soil is clayey and loamy with granular blocky structure on both the sites. The pH ranged from 7.1 to 7.72 0.1 for site I and from 5.5 to 8.0 f 0.1 for site 11; salinity and bulk density ranged from 0.1 per cent to 8 per cent and from 1.2 glcm3 to 1.5 g/cm3, respectively and soil moisture was about 0.4 f 1 per cent for both the sites. Similarly, total Kjeldahl nitrogen ranged from 1100 mg kg-' to 1900 mg kg-' for site I and 1700 mg kg-' to 9000 mg kg ' for site I1 and total organic carbon ranged from 18 mg g-' to 75 mg g ' for both the sites. A good correlation between nitrate concentration and various explosive process activities has been observed which gives substantial evidence in terms of contamination of the soil. High performance liquid chromatography analysis, which shows varied concentrations of RDX-HMX, NB, DNB, DNT, and TNT in the respective ranges 0.003-2.300 rng g-1, 0.002-0.350 mg g~1, 0.002-0.550 mg g-1, 0.004-0.041 mg g-1 and 0.010- 0.050 mg g-1 for site 1 and 0.002 - 0.013 mg g-1, 0.005 - 0.350 mg g-1, 0.003 - 0.080 mg g-1, 0.001- 0.100 mg g-1, 0.0001- 0.044 mg g ~a1n d 6*10-6- 0.080 mg g-1 for sites I1 has also indicated the contamination of soil by nitro-organics. These results serve as a valuable database for an ongoing project on the development of phytoremediation technology to detoxify such sites.
Grim, T.; Honza, Marcel
Roč. 56, č. 5 (2001), s. 549-556. ISSN 0006-3088 R&D Projects: GA ČR GA206/00/P046 Keywords : brood parasitism * mimicry * nest defence Subject RIV: EH - Ecology, Behaviour Impact factor: 0.208, year: 2001
Grootelaar, Hilke; Waterbolk, Tjalling; Winkels, Jakoline
This paper presents the results of eight case studies of post-defence hearings in a Dutch court, in which the judge was questioned about his role conception, judicial behaviour at the hearing was observed and parties were interviewed about their perception of procedural justice after the hearing. A
This study investigates altruistic behavior and interpersonal harassment of higher vocational students through questionnaires.It finds that the overall altruistic behavior level of higher vocational college students is high relatively;the level of interpersonal harassment is low relatively,though a few students with higher degree of interpersonal harassment.A negative correlation was observed between altruistic behavior and interpersonal harassment in this study： the higher is the level of altruistic behavior,the lower of the level of interpersonal harassment.The colleges should strengthen altruism education through the students＇ concern about their interpersonal harassment.On the other hand,the colleges should pay full attention to students＇ interpersonal harassment to help students minimize interpersonal problems.%本研究利用相关问卷对高职学生的利他行为和人际关系困扰进行了调查。调查发现高职院校学生总体利他行为水平较高,人际关系困扰较少,部分学生人际关系困扰较严重。本研究证明高职学生个体的利他行为与其人际关系困扰具有显著的负相关,利他行为水平越高,人际关系困扰越低。学校要利用学生对自身人际关系困扰的关注,加强利他思想的教育。同时,学校应该充分重视学生人际关系问题,帮助学生消除人际关系困扰。
Chabas, Hélène; van Houte, Stineke; Høyland-Kroghsbo, Nina Molin; Buckling, Angus; Westra, Edze R
Migration of hosts and parasites can have a profound impact on host-parasite ecological and evolutionary interactions. Using the bacterium Pseudomonas aeruginosa UCBPP-PA14 and its phage DMS3vir, we here show that immigration of naive hosts into coevolving populations of hosts and parasites can influence the mechanistic basis underlying host defence evolution. Specifically, we found that at high levels of bacterial immigration, bacteria switched from clustered regularly interspaced short palindromic repeats (CRISPR-Cas) to surface modification-mediated defence. This effect emerges from an increase in the force of infection, which tips the balance from CRISPR to surface modification-based defence owing to the induced and fixed fitness costs associated with these mechanisms, respectively. PMID:27581884
Camilla L. Krog
Full Text Available Orientation: Understanding the relationship between a project sponsor’s servant leadership traits and employee commitment, trust and innovative behaviour.Research purpose: This study aimed to understand the relationship, if any, between a project sponsor’s servant leadership traits of altruistic calling, emotional healing, wisdom, persuasive mapping and organisational stewardship and a project team’s empowerment, commitment, trust and innovative behaviour.Motivation of the study: Most project leadership studies focus on understanding the role and power position of the project manager, with very little research being dedicated to understanding the effect the leadership style has on the project team and project success.Research approach: A survey was conducted amongst a non-probability sample of 48 project team members from amongst a population of 257, comprising project managers, business analysts and IT staff of a medium sized fleet management organisation that is in the process of implementing an entirely new enterprise resource planning system.Main findings: Through inferential statistical analysis, using structural equation modelling and path analysis, it was determined that persuasive mapping has the strongest impact on employee innovative behaviour, followed by employee commitment and trust via the mediator of employee perceived empowerment. Wisdom and organisational stewardship had a negative impact on employee perceived empowerment.Practical/managerial implications: Project sponsors need to exhibit persuasive mapping, altruistic calling and emotional healing traits due to the significant influence that these have on employee innovative behaviour, commitment and trust, albeit through their perceived empowerment.Contribution/value-add: This study contributes to knowledge of leadership, more especially servant leadership and its significance in project management, which knowledge may contribute to project success
Jeremias J. de Klerk
Full Text Available Orientation: The statistical record of change and improvement interventions to deliver on expectations is notoriously poor. Yet, new interventions are started constantly.Research purpose: The aim is to provide an explanation to the lure behind interventions and to contribute to building a theory on plausible systems psychodynamic drivers and mechanisms of recurrent change interventions.Motivation for the study: This study provides insights into social defences in ways that did not receive much attention previously; specifically how defence mechanisms act as drivers for new change and improvement interventions.Research design, approach and method: A literature study, consisting of a literature review and a phenomenological analysis. The study was conducted from the systems psychodynamic approach.Main findings: Improvement interventions often represent defences that serve to contain anxieties or maintain fantasies. Four specific themes emerged: interventions defend the perception of being in control, they maintain the fantasy that one is busy with worthy actions to overcome challenges, they are defences against boredom or contain anxieties about incompetence, and they maintain the fantasy of being heroic leaders.Practical/managerial implications: The findings can assist leaders to understand their own defences in order to avoid embarking on non-essential interventions. This can free up much time, energy and effort to spend on other priorities, assisting organisations to achieve better results.Contribution/value-add: The study refutes the notion that improvement interventions are always rational coping mechanisms and highlights the role of improvement interventions as defences to reduce anxiety, even though they may contribute little to organisational survival in real terms.
Naomi J Fox
Full Text Available Parasitic helminths present one of the most pervasive challenges to grazing herbivores. Many macro-parasite transmission models focus on host physiological defence strategies, omitting more complex interactions between hosts and their environments. This work represents the first model that integrates both the behavioural and physiological elements of gastro-intestinal nematode transmission dynamics in a managed grazing system. A spatially explicit, individual-based, stochastic model is developed, that incorporates both the hosts' immunological responses to parasitism, and key grazing behaviours including faecal avoidance. The results demonstrate that grazing behaviour affects both the timing and intensity of parasite outbreaks, through generating spatial heterogeneity in parasite risk and nutritional resources, and changing the timing of exposure to the parasites' free-living stages. The influence of grazing behaviour varies with the host-parasite combination, dependent on the development times of different parasite species and variations in host immune response. Our outputs include the counterintuitive finding that under certain conditions perceived parasite avoidance behaviours (faecal avoidance can increase parasite risk, for certain host-parasite combinations. Through incorporating the two-way interaction between infection dynamics and grazing behaviour, the potential benefits of parasite-induced anorexia are also demonstrated. Hosts with phenotypic plasticity in grazing behaviour, that make grazing decisions dependent on current parasite burden, can reduce infection with minimal loss of intake over the grazing season. This paper explores how both host behaviours and immunity influence macro-parasite transmission in a spatially and temporally heterogeneous environment. The magnitude and timing of parasite outbreaks is influenced by host immunity and behaviour, and the interactions between them; the incorporation of both regulatory processes
Puttalingaiah, Basavaraju; Shetty, Nandini Prasad; Shetty, H. S.;
Aims: To investigate the infection biology of Colletotrichum sublineolum (isolate CP2126) and defence responses in leaves of resistant (SC146), intermediately resistant (SC326) and susceptible (BTx623) sorghum genotypes. Methods and Results: Infection biology and defence responses were studied...... decreases in formation of appressoria as well as accumulation of H2O2, HRGPs and phytoalexins. Concomitant with these inducible responses, fungal growth was stopped during or just after penetration in genotypes SC146 and SC326. High levels of H2O2 accumulating at late infection stages (5 days after...
Broader incorporation of inherent and passive safety design features has become a 'trademark' of many advanced reactor concepts, including several evolutionary designs and nearly all innovative small and medium sized design concepts. Ensuring adequate defence-in-depth is important for reactors of smaller output because many of them are being designed to allow more proximity to the user, specifically, when non-electrical energy products are targeted. Based on the activities recently performed by the International Atomic Energy Agency, the paper provides a summary description of the design features used to achieve defence in depth in the innovative concepts of small and medium sized reactors with fast neutron spectrum. (author)
WENRA published in 2010 a statement on safety objectives for new NPPs. Based on these objectives, WENRA decided to develop common positions, compiled in a booklet (available on www.wenra.org), on selected key safety issues for the design of new NPPs. One position presents WENRA’s Defence-in-Depth approach, describing WENRA’s expectation that multiple failure events and core melt accidents are considered in the original design of new nuclear power plants; another position presents expectations on the independence between different levels of Defence-in-Depth. (author)
Matessi, Giuliano; Carmagnani, Cristina; Griggio, Matteo;
petronia), a monomorphic species in which both sexes have a yellow breast patch, the size of which correlates with individual reproductive quality. We reduced the breast patch in a sample of females and compared the parental care of their partners (chick feeding and nest defence) with the parental care of...... males paired to sham-manipulated controls. Nest defence was assessed by placing a dummy predator on the nest box. Males of ornament-reduced females defended the nest less but did not feed the chicks less than males paired to control females. Our results only partially support male differential...
Randriamanana, Tendry R; Nybakken, Line; Lavola, Anu; Aphalo, Pedro J; Nissinen, Katri; Julkunen-Tiitto, Riitta
Plant defence theories have recently evolved in such a way that not only the quantity but also the quality of mineral nutrients is expected to influence plant constitutive defence. Recently, an extended prediction derived from the protein competition model (PCM) suggested that nitrogen (N) limitation is more important for the production of phenolic compounds than phosphorus (P). We aimed at studying sexual differences in the patterns of carbon allocation to growth and constitutive defence in relation to N and P availability in Populus tremula L. seedlings. We compared the gender responses in photosynthesis, growth and whole-plant allocation to phenolic compounds at different combination levels of N and P, and studied how they are explained by the main plant defence theories. We found no sexual differences in phenolic concentrations, but interestingly, slow-growing females had higher leaf N concentration than did males, and genders differed in their allocation priority. There was a trade-off between growth and the production of flavonoid-derived phenylpropanoids on one hand, and between the production of salicylates and flavonoid-derived phenylpropanoids on the other. Under limited nutrient conditions, females prioritized mineral nutrient acquisition, flavonoid and condensed tannin (CT) production, while males invested more in above-ground biomass. Salicylate accumulation followed the growth differentiation balance hypothesis as low N mainly decreased the production of leaf and stem salicylate content while the combination of both low N and low P increased the amount of flavonoids and CTs allocated to leaves and to a lesser extent stems, which agrees with the PCM. We suggest that such a discrepancy in the responses of salicylates and flavonoid-derived CTs is linked to their clearly distinct biosynthetic origins and/or their metabolic costs. PMID:24852570
At the end of the nineteenth century provincial bacteriological institutes were established in Belgium--in Liège, Mons, Namur and Brussels--in order to combat epidemics, to promote preventive medicine and to pursue the successful research of Louis Pasteur and Robert Koch. Similar laboratories existed at the universities of Ghent, Louvain and Brussels. The image building played an important role for both kinds of institutes, as bacteriology in pioneering phase had to be publicly confirmed as a new, valuable discipline. However, the directors of provincial and academic institutes--with the same academic training though--were awarded with different qualities at their jubilees, fitting with the purposes and the self-image of their respective institutions, either provincial authorities or universities. The image of academic directors was guided by academic decorum: Emile van Ermengem, Edmond Destrée and Joseph Denys were represented as savants, solely devoted to pure science and paternally educating young researchers, notwithstanding the fact that their laboratories had humanitarian merits as well. On the other hand, the discourse on the first provincial directors--Ernest Malvoz, Martin Herman, Achille Haibe--emphasized their altruistic commitment and their solid work for the provincial government. Jules Bordet, a internationally rewarded scientist, professor and provincial director of the Pasteur Institute in Brussels, was celebrated with both sorts of discourses. PMID:22586760
Sears, Brittany F.; Snyder, Paul W.; Rohr, Jason R.
Summary There is growing interest in the role that life-history traits of hosts, such as their ‘pace-of-life’, play in the evolution of resistance and tolerance to parasites.Theory suggests that, relative to host species that have high syntopy (local spatial and temporal overlap) with parasites, host species with low syntopy should have lower selection pressures for more constitutive (always present) and costly defences, such as tolerance, and greater reliance on more inducible and cheaper defences, such as behaviour. Consequently, we postulated that the degree of host–parasite syntopy, which is negatively correlated with host pace-of-life (an axis reflecting the developmental rate of tadpoles and the inverse of their size at metamorphosis) in our tadpole–parasitic cercarial (trematode) system, would be a negative and positive predictor of behavioural resistance and tolerance, respectively.To test these hypotheses, we exposed seven tadpole species to a range of parasite (cercarial) doses crossed with anaesthesia treatments that controlled for anti-parasite behaviour. We quantified host behaviour, successful and unsuccessful infections, and each species’ reaction norm for behavioural resistance and tolerance, defined as the slope between cercarial exposure (or attempted infections) and anti-cercarial behaviours and mass change, respectively. Hence, tolerance is capturing any cost of parasite exposure.As hypothesized, tadpole pace-of-life was a significant positive predictor of behavioural resistance and negative predictor of tolerance, a result that is consistent with a trade-off between behavioural resistance and tolerance across species that warrants further investigation. Moreover, these results were robust to considerations of phylogeny, all possible re-orderings of the three fastest or slowest paced species, and various measurements of tolerance.These results suggest that host pace-of-life and host–parasite syntopy are powerful drivers of both the
Sears, Brittany F; Snyder, Paul W; Rohr, Jason R
There is growing interest in the role that life-history traits of hosts, such as their 'pace-of-life', play in the evolution of resistance and tolerance to parasites. Theory suggests that, relative to host species that have high syntopy (local spatial and temporal overlap) with parasites, host species with low syntopy should have lower selection pressures for more constitutive (always present) and costly defences, such as tolerance, and greater reliance on more inducible and cheaper defences, such as behaviour. Consequently, we postulated that the degree of host-parasite syntopy, which is negatively correlated with host pace-of-life (an axis reflecting the developmental rate of tadpoles and the inverse of their size at metamorphosis) in our tadpole-parasitic cercarial (trematode) system, would be a negative and positive predictor of behavioural resistance and tolerance, respectively. To test these hypotheses, we exposed seven tadpole species to a range of parasite (cercarial) doses crossed with anaesthesia treatments that controlled for anti-parasite behaviour. We quantified host behaviour, successful and unsuccessful infections, and each species' reaction norm for behavioural resistance and tolerance, defined as the slope between cercarial exposure (or attempted infections) and anti-cercarial behaviours and mass change, respectively. Hence, tolerance is capturing any cost of parasite exposure. As hypothesized, tadpole pace-of-life was a significant positive predictor of behavioural resistance and negative predictor of tolerance, a result that is consistent with a trade-off between behavioural resistance and tolerance across species that warrants further investigation. Moreover, these results were robust to considerations of phylogeny, all possible re-orderings of the three fastest or slowest paced species, and various measurements of tolerance. These results suggest that host pace-of-life and host-parasite syntopy are powerful drivers of both the strength and type
Biziou-van-Pol, Laura; Novaro, Arianna; Liberman, Andrés Occhipinti; Capraro, Valerio
The focus of this paper is the moral conflict between lying aversion and prosociality. What does telling a white lie signal about a person's prosocial tendencies? How does believing a possibly untruthful message signal about a listener's prosocial tendencies? To answer these questions, we conducted a 2x3 experiment. In the first stage we measured altruistic tendencies using a Dictator Game and cooperative tendencies using a Prisoner's dilemma. In the second stage, we used a sender-receiver game to measure aversion to telling a Pareto white lie (i.e., a lie that helps both the liar and the listener), aversion to telling an altruistic white lie (i.e., a lie that helps the listener at the expense of the liar), and skepticism towards believing a possibly untruthful message. We found three major results: (i) both altruism and cooperation are positively correlated with aversion to telling a Pareto white lie; (ii) neither altruism nor cooperation are significantly correlated with aversion to telling an altruistic wh...
The ongoing economic crisis forces seeking solutions enabling the development of NATO's defence capabilities in the era of cuts in defence budgets. An example of this is Smart Defence initiative, which allows member states to participate in multinational projects oriented into the needs of the whole NATO. Capabilities in the area of aviation are considered as one of the key priorities of NATO, somany projects in Smart Defence initiative relate to aviation. The ar...
Over the past years, in books and journals (this journal included), N. Maxwell launched a ferocious attack on B. C. van Fraassen’s view of science called Constructive Empiricism (CE). This attack has been totally ignored. Must we conclude from this silence that no defence is possible and that a fort
Findings from parent-infant observational research have stimulated the development of intersubjective models of psychotherapeutic action. These models have brought out the infant as an interactive partner with the parent. Conversely, interest in describing the individual psyche of the baby has decreased, especially the unconscious levels of his/her experiences and representations. In parallel, clinicians and researchers have been less prone to apply classical psychoanalytic concepts when describing the internal world of the infant. The author argues that this is inconsistent with the fact that psychoanalytic theory, from its inception, was founded on speculations of the infant's mind. He investigates one such concept from classical theory; the defence. Specifically, he investigates if selective gaze avoidance in young babies may be described as a defence or even a defence mechanism. The investigation links with Selma Fraiberg's discussion of the phenomenon and also with Freud's conception of defence. The author also compares his views on the baby as a subject with those suggested by infant researchers, for example, Stern and Beebe. The discussion is illustrated by vignettes from a psychoanalytic therapy with a 3 month-old girl and her mother. PMID:25988970
This brief paper examines the issues of awareness and application of a Learning Management System (LMS) used at the National Defence University of Malaysia (NDUM), Kuala Lumpur Malaysia. The paper argues that due to the discouraging responses from academics at the university on using the LMS, proactive measures must be taken immediately in order…
Jing, Jingying; Raaijmakers, Ciska; Kostenko, Olga; Kos, Martine; Mulder, P.P.J.; Bezemer, T. Martijn
Competition and herbivory are two major factors that can influence plant growth and plant defence. Although these two factors are often studied separately, they do not operate independently. We examined how aboveground herbivory by beet armyworm larvae (Spodoptera exigua) and belowground herbivory b
Kyjaková, Pavlína; Dolejšová, Klára; Krasulová, Jana; Bednárová, Lucie; Hadravová, Romana; Pohl, Radek; Hanus, Robert
Roč. 115, č. 4 (2015), s. 818-825. ISSN 0024-4066 R&D Projects: GA ČR GP13-25354P Institutional support: RVO:61388963 Keywords : termites * soldiers * chemical defence * diterpene * cavitene * frontal gland Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 2.264, year: 2014
The publication of this IAEA technical document represents the conclusion of a task, initiated in 1995, devoted to defence in depth in future reactors. It focuses mainly on the next generation of LWRs, although many general considerations may also apply to other types of reactors
"The Prime Minister Mir Zafarullah Khan Jamali has appreciated role of Pakistan Atomic Energy Council (PAEC) for its contribution to the scientific development and defence needs of the country. He directed that all resources and energy be devoted to the development of human resource and infrastructure for socio-economic uplift of the nation" (1 page).
European Security and Defence Policy (ESDP) represents the actual Security Policy of the European Union. The Lisbon Treaty represented a new chapter in strengthening the institutional framework to address this area, noting the establishment of the post of High Representative for Foreign and Security Policy, the establishment of the European External Action Service (EEAS) and concrete steps in implementing the provisions on CSDP objectives.
The antimicrobial and haemolytic activities of a host defence peptide can be controlled by modification as a propeptide of reduced net charge which can be processed by neutrophil elastase, a serine protease involved in chronic airway inflammation and infections associated with cystic fibrosis.
"Disaster education" is a fledgling area of study in lifelong education. Many countries educate their populations for disasters, to mitigate potential damage and loss of life, as well as contribute to national security. In this paper, which draws on interview data from the German Federal Office for Civil Defence and Disaster Assistance…
J. V. Shankar; V. H. Potty; S. P. Pillai
The Central Food Technological Research Institute, Mysore, working under the council of Scientific & Industrial Research has developed a number of processes and techniques some of which are relevent to Defence needs. Items like spray dried egg powder and canned drinking water are already in use by the services while others may find application in future.
K. Tibori Szabó
The legality of preemptive strikes is one of the most controversial questions of contemporary international law. At the core of this controversy stands the temporal dimension of self-defence: when and for how long can a state defend itself against an armed attack? Can it resort to armed force before
Published in 1979, Richard Dyer’s ‘In Defence of Disco’ is one of the best-read but relatively little-used essays in pop music studies, queer studies and cultural studies. With his essay, not only does Dyer demystify the ‘authenticity’ of music genres such as folk and rock, but also validates and ce
Hooff, M.V.; McFarlane, A.C.; Davies, C.E.; Searle, A.K.; Fairweather-Schmidt, A.K.; Verhagen, A.F.; Benassi, H.; Hodson, S.E.
BACKGROUND: The Australian Defence Force (ADF) Mental Health Prevalence and Wellbeing Study (MHPWS) is the first study of mental disorder prevalence in an entire military population. OBJECTIVE: The MHPWS aims to establish mental disorder prevalence, refine current ADF mental health screening methods
Giron, D.; Frago, E.; Glevarec, G.; Pieterse, C.M.J.; Dicke, M.
Plant hormones play important roles in regulating plant growth and defence by mediating developmental processes and signalling networks involved in plant responses to a wide range of parasitic and mutualistic biotic interactions. Plants are known to rapidly respond to pathogen and herbivore attack b
Giron, D.; Frago, E.; Glevarec, G.; Pieterse, C.M.J.; Dicke, M.
1. Plant hormones play important roles in regulating plant growth and defence by mediating developmental processes and signalling networks involved in plant responses to a wide range of parasitic and mutualistic biotic interactions. 2. Plants are known to rapidly respond to pathogen and herbivore at
P. Asikainen; T.J. Ruotsalainen; J.J.W. Mikkonen; A. Koistinen; C. ten Bruggenkate; A.M. Kullaa
The oral epithelium together with the saliva and its components forms a complex structure which is the first line of defence in the oral cavity. The surface of superficial cells of the oral epithelium contains ridge-like folds, microplicae (MPL), which are typical of the surfaces of areas covered wi
The development in location-based mobile media has led to the popularity of its use for place experiences. This study explored the concept of territoriality, which is suggested as the underlying human behaviour that influences consumers’ mobility and experience stimulated by the social gaming...... feature of location-based media. From an exploratory investigation with a series of focus group discussions with users of location-based media, this study observed the activities of territorial tagging for the purposes of territorial claim and defence to gain and maintain the perceived territorial control...... over resources and rewards attached to certain places. The ability of location-based media to make the physical territory to interact with informational devices enables territorial behaviour to manifest in the consumption of local establishments, making location-based media a powerful tool...
Narayan, Siddharth; Beck, Michael W; Reguero, Borja G; Losada, Iñigo J; van Wesenbeeck, Bregje; Pontee, Nigel; Sanchirico, James N; Ingram, Jane Carter; Lange, Glenn-Marie; Burks-Copes, Kelly A
There is great interest in the restoration and conservation of coastal habitats for protection from flooding and erosion. This is evidenced by the growing number of analyses and reviews of the effectiveness of habitats as natural defences and increasing funding world-wide for nature-based defences-i.e. restoration projects aimed at coastal protection; yet, there is no synthetic information on what kinds of projects are effective and cost effective for this purpose. This paper addresses two issues critical for designing restoration projects for coastal protection: (i) a synthesis of the costs and benefits of projects designed for coastal protection (nature-based defences) and (ii) analyses of the effectiveness of coastal habitats (natural defences) in reducing wave heights and the biophysical parameters that influence this effectiveness. We (i) analyse data from sixty-nine field measurements in coastal habitats globally and examine measures of effectiveness of mangroves, salt-marshes, coral reefs and seagrass/kelp beds for wave height reduction; (ii) synthesise the costs and coastal protection benefits of fifty-two nature-based defence projects and; (iii) estimate the benefits of each restoration project by combining information on restoration costs with data from nearby field measurements. The analyses of field measurements show that coastal habitats have significant potential for reducing wave heights that varies by habitat and site. In general, coral reefs and salt-marshes have the highest overall potential. Habitat effectiveness is influenced by: a) the ratios of wave height-to-water depth and habitat width-to-wavelength in coral reefs; and b) the ratio of vegetation height-to-water depth in salt-marshes. The comparison of costs of nature-based defence projects and engineering structures show that salt-marshes and mangroves can be two to five times cheaper than a submerged breakwater for wave heights up to half a metre and, within their limits, become more cost
Full Text Available There is great interest in the restoration and conservation of coastal habitats for protection from flooding and erosion. This is evidenced by the growing number of analyses and reviews of the effectiveness of habitats as natural defences and increasing funding world-wide for nature-based defences-i.e. restoration projects aimed at coastal protection; yet, there is no synthetic information on what kinds of projects are effective and cost effective for this purpose. This paper addresses two issues critical for designing restoration projects for coastal protection: (i a synthesis of the costs and benefits of projects designed for coastal protection (nature-based defences and (ii analyses of the effectiveness of coastal habitats (natural defences in reducing wave heights and the biophysical parameters that influence this effectiveness. We (i analyse data from sixty-nine field measurements in coastal habitats globally and examine measures of effectiveness of mangroves, salt-marshes, coral reefs and seagrass/kelp beds for wave height reduction; (ii synthesise the costs and coastal protection benefits of fifty-two nature-based defence projects and; (iii estimate the benefits of each restoration project by combining information on restoration costs with data from nearby field measurements. The analyses of field measurements show that coastal habitats have significant potential for reducing wave heights that varies by habitat and site. In general, coral reefs and salt-marshes have the highest overall potential. Habitat effectiveness is influenced by: a the ratios of wave height-to-water depth and habitat width-to-wavelength in coral reefs; and b the ratio of vegetation height-to-water depth in salt-marshes. The comparison of costs of nature-based defence projects and engineering structures show that salt-marshes and mangroves can be two to five times cheaper than a submerged breakwater for wave heights up to half a metre and, within their limits, become
Renato A Sarmento
Full Text Available Herbivores may interact with each other through resource competition, but also through their impact on plant defence. We recently found that the spider mite Tetranychus evansi down-regulates plant defences in tomato plants, resulting in higher rates of oviposition and population growth on previously attacked than on unattacked leaves. The danger of such down-regulation is that attacked plants could become a more profitable resource for heterospecific competitors, such as the two-spotted spider mite Tetranychus urticae. Indeed, T. urticae had an almost 2-fold higher rate of oviposition on leaf discs on which T. evansi had fed previously. In contrast, induction of direct plant defences by T. urticae resulted in decreased oviposition by T. evansi. Hence, both herbivores affect each other through induced plant responses. However, when populations of T. evansi and T. urticae competed on the same plants, populations of the latter invariably went extinct, whereas T. evansi was not significantly affected by the presence of its competitor. This suggests that T. evansi can somehow prevent its competitor from benefiting from the down-regulated plant defence, perhaps by covering it with a profuse web. Indeed, we found that T. urticae had difficulties reaching the leaf surface to feed when the leaf was covered with web produced by T. evansi. Furthermore, T. evansi produced more web when exposed to damage or other cues associated with T. urticae. We suggest that the silken web produced by T. evansi serves to prevent competitors from profiting from down-regulated plant defences.
Full Text Available Plant innate immunity is composed of two layers--a basal immunity, and a specific effector-triggered immunity, which is often accompanied by hypersensitive cell death. Initiation of cell death depends on a complex network of signalling pathways. The phytohormone auxin as central regulator of plant growth and development represents an important component for the modulation of plant defence. In our previous work, we showed that cell death is heralded by detachment of actin from the membrane. Both, actin response and cell death, are triggered by the bacterial elicitor harpin in grapevine cells. In this study we investigated, whether harpin-triggered actin bundling is necessary for harpin-triggered cell death. Since actin organisation is dependent upon auxin, we used different auxins to suppress actin bundling. Extracellular alkalinisation and transcription of defence genes as the basal immunity were examined as well as cell death. Furthermore, organisation of actin was observed in response to pharmacological manipulation of reactive oxygen species and phospholipase D. We find that induction of defence genes is independent of auxin. However, auxin can suppress harpin-induced cell death and also counteract actin bundling. We integrate our findings into a model, where harpin interferes with an auxin dependent pathway that sustains dynamic cortical actin through the activity of phospholipase D. The antagonism between growth and defence is explained by mutual competition for signal molecules such as superoxide and phosphatidic acid. Perturbations of the auxin-actin pathway might be used to detect disturbed integrity of the plasma membrane and channel defence signalling towards programmed cell death.
Dr. Theodore Metaxas
Full Text Available This article aims to clarify how the level of defence expenditures affected security poli-cy in the post-World War II Europe and the United States till the present day. We first analyze theoretically the issue of a nation’s power through its defence outlays. We then proceed to the examination of how security policy was formulated during Cold War and afterwards for both Europe and the United States through their defence ex-penditures. By comparing European to United States defence budgets ceilings we found that the European military capabilities are undermined by the low level of the defence budget which is provided by the European Union member states as a whole, as well as by the lack of homogeneity in military means. By contrast, we noticed that the historically large US defence expenditures were one of the major reasons for the US global hegemony during Cold war and afterwards. We also examine the implica-tions that defence expenditures have on military industry, macroeconomic perfor-mance and geopolitics and the correlation that arises among them.
Full Text Available Roberto Ago, the International Law Commission’s second Special Rapporteur on the topic of state responsibility for internationally wrongful acts, defined self-defence as a faculté of a state to use force in response to an act of another state through which a breach of the principal obligation under Article 2(4 Charter is committed. On this basis, he then inserted a provision in Chapter V to Part One of the Draft Articles on State Responsibility expressing self-defence as a specific factual circumstance precluding the wrongfulness of the use of force which constitutes a response to state aggression. This conception of self-defence, although misunderstood from the onset, remained in the backdrop of the study of the law of state responsibility for a considerable period. It was only dismantled during the reign of the last Special Rapporteur on the topic of state responsibility, James Crawford. The last Rapporteur, at the onset, submitted that it is not the function of the Draft Articles to specify the content of the primary rules, including that referred to in Article 51 Charter. He then redefined the function of the circumstance of self-defence as that of precluding the wrongfulness of non-performance of certain obligations other than the general prohibition insofar as such non-performance is connected with the exercise of the right under Article 51 Charter.This contribution first scrutinises this paradigmatic shift and finds it to be symptomatic of the conviction on the part of Crawford that the notion of self-defence could also encompass the use of force against speculative threats of state origin as well as actual threats that emanate from individuals or groups which are disconnected from the organisation of any state. It then uses this finding as a springboard towards the examination of the controversy surrounding the notion of self-defence under international law. In that connection, it first outlines the findings of the World Court on the
The concept of defence-in-depth (DID) is fundamental to the safety of nuclear power plants. It calls for multiple successive methods or barriers against radioactive release to the environment. DID principle is partly reflected in a probabilistic safety assessment (PSA), but not all of the DID levels are included in the model. In addition, events included in PSA are not typically labelled with DID information. PSA could however be a powerful tool to assess the status of various DID levels in an NPP. This work is a start of a development of the PSA-methodology towards an assessment of DID levels. It includes: 1) mapping of conditions that should be considered for the defence in depth levels, and 2) definition of quantitative measures that should be considered for the defence in depth levels. The work has been limited to loss-of-coolant accidents (LOCA) and DID levels 1 and 2, i.e., prevention of abnormal operation and failures and control of abnormal operation and detection of failures. Examples are chosen both from power operation LOCAs and LOCAs during cold shutdown. The methods that are used today in PSA are applicable for evaluating defence-in-depth levels 1 and 2. In the framework of these methodologies there are many different conditions and measures used. Failure data can be determined through: human reliability analysis (HRA), risk-informed in-service-inspection (RI-ISI) methodology, system reliability analysis and directly from plant specific failure data for the components. Many DID activities against LOCA are not explicitly modelled in typical PSA-studies. The risk importance of in-service-inspection is analysed and quantified in RI-ISI applications but so far results from RI-ISI have not been incorporated into PSA. Very few leakage detection systems are modelled in PSA-studies. Normally leakage detection systems that is part of the automatic actuation system are modelled while leakage detection systems in DID levels 1 and 2 typically are omitted. DID
Narayan, Siddharth; Beck, Michael W.; Reguero, Borja G.; Losada, Iñigo J.; van Wesenbeeck, Bregje; Pontee, Nigel; Sanchirico, James N.; Ingram, Jane Carter; Lange, Glenn-Marie; Burks-Copes, Kelly A.
There is great interest in the restoration and conservation of coastal habitats for protection from flooding and erosion. This is evidenced by the growing number of analyses and reviews of the effectiveness of habitats as natural defences and increasing funding world-wide for nature-based defences–i.e. restoration projects aimed at coastal protection; yet, there is no synthetic information on what kinds of projects are effective and cost effective for this purpose. This paper addresses two issues critical for designing restoration projects for coastal protection: (i) a synthesis of the costs and benefits of projects designed for coastal protection (nature-based defences) and (ii) analyses of the effectiveness of coastal habitats (natural defences) in reducing wave heights and the biophysical parameters that influence this effectiveness. We (i) analyse data from sixty-nine field measurements in coastal habitats globally and examine measures of effectiveness of mangroves, salt-marshes, coral reefs and seagrass/kelp beds for wave height reduction; (ii) synthesise the costs and coastal protection benefits of fifty-two nature-based defence projects and; (iii) estimate the benefits of each restoration project by combining information on restoration costs with data from nearby field measurements. The analyses of field measurements show that coastal habitats have significant potential for reducing wave heights that varies by habitat and site. In general, coral reefs and salt-marshes have the highest overall potential. Habitat effectiveness is influenced by: a) the ratios of wave height-to-water depth and habitat width-to-wavelength in coral reefs; and b) the ratio of vegetation height-to-water depth in salt-marshes. The comparison of costs of nature-based defence projects and engineering structures show that salt-marshes and mangroves can be two to five times cheaper than a submerged breakwater for wave heights up to half a metre and, within their limits, become more
Oster, Michael; Scheel, Mathias; Muráni, Eduard; Ponsuksili, Siriluck; Zebunke, Manuela; Puppe, Birger; Wimmers, Klaus
Defining phenotypes according to molecular features would promote the knowledge of functional traits like behaviour in both human and animal research. Beside physiological states or environmental factors, an innate predisposition of individual coping strategies was discussed, including the proactive and reactive pattern. According to backtest reactivity, animals assigned as high-resisting (proactive) and low-resisting (reactive) were immune challenged with tetanus toxoid in a time course experiment. Using the Affymetrix platform and qPCR, individual coping characteristics were reflected as gene expression signatures in porcine peripheral blood mononuclear cells (PBMC) at naïve state (day 0) and in response to the model antigen (day 14, day 28, and day 140). Further, the blood cell count was analysed at all stages. On the transcriptional level, processes acting on cell communication, vasculogenesis, and blood coagulation were highlighted in high-resisting animals at naïve state (day 0), temporarily blurred due to immune challenge (day 14) but subsequently restored and intensified (day 28). Notably, similar amounts of white and red blood cells, platelets and haematocrit between high-resisting and low-resisting samples suggest coping-specific expression patterns rather than alterations in blood cell distribution. Taken together, the gene expression patterns indicate that proactive pigs might favour molecular pathways enabling an effective strategy for defence and recovery. This corroborates the previously suggested belief, that proactive animals are prone to an increased number of injuries as an evolutionary inherited mechanism. In contrast to previous assumptions, coping-specific immunity in pigs lacks inherited shifts between cellular and humoral immune responses. PMID:25793368
Full Text Available Defining phenotypes according to molecular features would promote the knowledge of functional traits like behaviour in both human and animal research. Beside physiological states or environmental factors, an innate predisposition of individual coping strategies was discussed, including the proactive and reactive pattern. According to backtest reactivity, animals assigned as high-resisting (proactive and low-resisting (reactive were immune challenged with tetanus toxoid in a time course experiment. Using the Affymetrix platform and qPCR, individual coping characteristics were reflected as gene expression signatures in porcine peripheral blood mononuclear cells (PBMC at naïve state (day 0 and in response to the model antigen (day 14, day 28, and day 140. Further, the blood cell count was analysed at all stages. On the transcriptional level, processes acting on cell communication, vasculogenesis, and blood coagulation were highlighted in high-resisting animals at naïve state (day 0, temporarily blurred due to immune challenge (day 14 but subsequently restored and intensified (day 28. Notably, similar amounts of white and red blood cells, platelets and haematocrit between high-resisting and low-resisting samples suggest coping-specific expression patterns rather than alterations in blood cell distribution. Taken together, the gene expression patterns indicate that proactive pigs might favour molecular pathways enabling an effective strategy for defence and recovery. This corroborates the previously suggested belief, that proactive animals are prone to an increased number of injuries as an evolutionary inherited mechanism. In contrast to previous assumptions, coping-specific immunity in pigs lacks inherited shifts between cellular and humoral immune responses.
Ric, Angel; Hristovski, Robert; Gonçalves, Bruno; Torres, Lorena; Sampaio, Jaime; Torrents, Carlota
The aim of this study was to identify the dynamics of tactical behaviour emerging on different timescales in football small-sided games and to quantify short- and long-term exploratory behaviour according to the number of opponents. Two teams of four professional male footballers played small-sided games against two different teams with a variable number of opponents (3, 5 and 7). Data were collected using a combination of systematic observation and a non-differential global positioning system (15 Hz). The temporal diversity and structural flexibility of the players were determined by calculating the dynamic overlap order parameter q, entropy and trapping strength. Analysis of the exploratory dynamics revealed two different timescales, forming a different metastable landscape of action for each constraint. Fast dynamics lasted on average a few seconds and consisted of changes in tactical patterns. The long timescale corresponded to the shared tasks of offence and defence lasting tens of seconds. The players' tactical diversity decreased with an increasing number of opponents, especially in defence. Manipulating numerical imbalance is likely to promote changes in the diversity, unpredictability and flexibility of tactical solutions. The fact that the temporally nested structure of constraints shaped the emergence of tactical behaviour provides a new rationale for practice task design. The manipulation of numerical imbalance on the timescale of a few tens of seconds, on which the exploratory behaviour of players saturates, may help coaches to optimise the exploratory efficiency of the small-sided games. PMID:26758958
Constantiou, Ioanna D.; Lehrer, Christiane; Hess, Thomas
on the continuance of LBS use and indicate changes in individuals' information retrieval behaviours in everyday life. In particular, the distinct value dimension of LBS in specific contexts of use changes individuals' behaviours towards accessing location-related information....
Review of: Organizational Behaviour in Construction / Anthony Walker (Wiley-Blackwell,2011 336 pp)......Review of: Organizational Behaviour in Construction / Anthony Walker (Wiley-Blackwell,2011 336 pp)...
Newman, Mari-Anne; Dow, J. Maxwell; Molinaro, Antonio;
the triggering of defence responses or to the priming of the plant to respond more rapidly and/or to a greater degree to subsequent pathogen challenge. LPS from symbiotic bacteria can have quite different effects on plants to those of pathogens. Some details are emerging of the structures within LPS...... that are responsible for induction of these different plant responses. The lipid A moiety is not solely responsible for all of the effects of LPS in plants; core oligosaccharide and O-antigen components can elicit specific responses. Here, we review the effects of LPS in induction of defence......-related responses in plants, the structures within LPS responsible for eliciting these effects and discuss the possible nature of the (as yet unidentified) LPS receptors in plants....
Full Text Available One of the goals that Partnership for Peace has set, within domain of geospatial information, is the implementation of a military geoinformation system. Besides this important strategic objective for the Republic of Croatia, the military geoinformation system will enhance activities of the Ministry of Defence and Armed Forces and in such way improve national defence and cooperation with NATO members and members of the Partnership for Peace. This paper describes overall system principles based on relevant standards from domain of geospatial information. The emphasis is on the design of the conceptual data model and the object catalogue as main objective in the first phase of the whole project. Within this first phase of the project not only conceptual data model and object catalogue were created, but also a GML application scheme that will serve as basis for data exchange with all anticipated users of the system.
Burstein, David; Sun, Christine L.; Brown, Christopher T.; Sharon, Itai; Anantharaman, Karthik; Probst, Alexander J.; Thomas, Brian C.; Banfield, Jillian F.
Current understanding of microorganism–virus interactions, which shape the evolution and functioning of Earth's ecosystems, is based primarily on cultivated organisms. Here we investigate thousands of viral and microbial genomes recovered using a cultivation-independent approach to study the frequency, variety and taxonomic distribution of viral defence mechanisms. CRISPR-Cas systems that confer microorganisms with immunity to viruses are present in only 10% of 1,724 sampled microorganisms, compared with previous reports of 40% occurrence in bacteria and 81% in archaea. We attribute this large difference to the lack of CRISPR-Cas systems across major bacterial lineages that have no cultivated representatives. We correlate absence of CRISPR-Cas with lack of nucleotide biosynthesis capacity and a symbiotic lifestyle. Restriction systems are well represented in these lineages and might provide both non-specific viral defence and access to nucleotides. PMID:26837824
Bjarnsholt, Thomas; Givskov, Michael Christian
Conventional antibiotics target the growth and the basal life processes of bacteria leading to growth arrest and cell death. The selective force that is inherently linked to this mode of action eventually selects out antibiotic-resistant variants. The most obvious alternative to antibiotic...... rise to a new 'drug target rush'. Recently, QS has been shown to be involved in the development of tolerance to various antimicrobial treatments and immune modulation. The regulation of virulence via QS confers a strategic advantage over host defences. Consequently, a drug capable of blocking QS is...... likely to increase the susceptibility of the infecting organism to host defences and its clearance from the host. The use of QS signal blockers to attenuate bacterial pathogenicity, rather than bacterial growth, is therefore highly attractive, particularly with respect to the emergence of multi...
Bjarnsholt, Thomas; Givskov, Michael Christian
Conventional antibiotics target the growth and the basal life processes of bacteria leading to growth arrest and cell death. The selective force that is inherently linked to this mode of action eventually selects out antibiotic-resistant variants. The most obvious alternative to antibiotic...... rise to a new 'drug target rush'. Recently, QS has been shown to be involved in the development of tolerance to various antimicrobial treatments and immune modulation. The regulation of virulence via QS confers a strategic advantage over host defences. Consequently, a drug capable of blocking QS is...... likely to increase the susceptibility of the infecting organism to host defences and its clearance from the host. The use of QS signal blockers to attenuate bacterial pathogenicity, rather than bacterial growth, is therefore highly attractive, particularly with respect to the emergence of multi...
Bricknell, Martin; Terrell, A; Ross, D; White, D
This paper is a narrative of the policies, procedures, mitigations and observations of the application of Force Health Protection measures applied by the Ministry of Defence (MOD) for the deployment of military personnel to West Africa as part of the UK contribution to the international response to the Ebola crisis from July 2014 to July 2015. The MOD divided the threat into three risk categories: risk from disease and non-battle injury, Ebola risk for non-clinical duties and Ebola risk for healthcare workers. Overall risk management was directed and monitored by the OP GRITROCK Force Health Protection Board. There were six cases of malaria, four outbreaks of gastrointestinal disease, two needlestick injuries in Ebola-facing healthcare workers, one MOD Ebola case and five non-needlestick, high-risk exposures. This experience reinforces the requirement for the Defence Medical Services to have a high level of organisational competence to advise on Force Health Protection for the MOD. PMID:26744191
Full Text Available In the paper the author proposes that effectively and efficiently addressing cyber crime requires a shift in paradigm. For businesses and government departments alike the focus should be on prevention, rather than the prosecution of cyber criminals. The Defence in Depth strategy poses a practical solution for achieving Information Assurance in todayâ€™s highly networked environments. In a world where â€œabsolute securityâ€ is an unachievable goal, the concept of Information Assurance poses significant benefits to securing one of an organizationâ€™s most valuable assets: Information. It will be argued that the approach of achieving Information Assurance within an organisation, coupled with the implementation of a Defence in Depth strategy can ensure that information is kept secure and readily available and provides a competitive advantage to those willing to invest and maintain such a strategy.
Full Text Available As the SA Defence Force celebrates its 75th anniversary, it can look back with pride at a truly remarkable history. Established just two years after Union, the fledging force was to be severely tested within the first two years of its existence to a degree perhaps unparalleled in the history of modern armies. Just over a year after its formation, when it still existed more on paper than in fact, the Union Defence Force (UDF was called upon to suppress a violent industrial strike on the Reef. Having passed its first test with flying colours, the UDF was confronted a few months later by the far more serious crises of internal rebellion and World War. Once again, however, the young organization proved equal to the occasion, and by the end of the Great War the UDF had developed into a battle-hardened, professional force respected the world over for its prowess, courage and endurance in the field.
Carlos Echeverría Jesús
Full Text Available Cooperation between Spain and the Maghreb states in the area of defence represents a sphere that includes long-term historical links (for example, with Morocco with other relations that have been developing in recent years, and at varying rates of intensity. Theprogressive normalising of the situation in Algeria since the 1990s, the raising of the UN embargo against Libya and the rise of what are called “new dangers” (all kinds of illegal trading and a style of terrorism that is increasingly transnational and lethal has led the states together with Mauritania and Tunisia to call for aid and cooperation from members such as Spain. Meanwhile, the revitalisation of the 5+5 group, even though it does not involve greater sub-regional cooperation in the Maghreb region, is encouraging North-South links which had until then been bilateralised, and since December 2004 the group has included the issue of defence on its agenda.
function and evolution. Further, it contributes to our understanding of the formation and role of biosynthetic gene clusters in plant chemical defence. The bifurcation in hydroxynitrile glucoside biosynthesis and catabolism observed in Lotus japonicus makes it a very suitable model system to study the......Plants are sessile organisms well-known to produce a vast array of chemical compounds of which many are used in chemical defence against herbivores and pathogens. The biosynthesis of these plant chemical defence compounds poses a considerable risk of self-toxicity for the plant itself. Several...... types of adaptations enable plants to avoid the potential lethal effects of their own defence compounds. These adaptations include detoxification and stabilization by glycosylation and the genomic clustering of biosynthetic pathway genes. These two types are the main focus of this PhD thesis on...
Gens Solé, Antonio
The paper reviews in summary form the generalised behaviour of soils under nonisothermal and chemically varying conditions. This generalised soil behaviour underlies the performance of a number of ground improvement techniques. The behaviour of frozen soil is examined first showing that some concepts of unsaturated soil mechanics appear to be readily applicable. Afterwards, the observation that volumetric behaviour of saturated and unsaturated soils at high temperature is similar, leads to th...
Van Hooff, Miranda; McFarlane, Alexander C; Christopher E. Davies; Searle, Amelia K.; Fairweather-Schmidt, A Kate; Verhagen, Alan; Benassi, Helen; Stephanie E Hodson
Background: The Australian Defence Force (ADF) Mental Health Prevalence and Wellbeing Study (MHPWS) is the first study of mental disorder prevalence in an entire military population.Objective: The MHPWS aims to establish mental disorder prevalence, refine current ADF mental health screening methods, and identify specific occupational factors that influence mental health. This paper describes the design, sampling strategies, and methodology used in this study.Method: At Phase 1, approximately ...
Wu, Wen; Wang, Xiaohua; Paull, David; Kesby, Julie
Environmental management of military activities is of growing global concern by defence forces. As one of the largest landholders in Australia, the Australian Defence Force (ADF) is increasingly concerned with sustainable environmental management. This paper focuses on how the ADF is maintaining effective environmental management, especially in environmentally sensitive marine protected areas. It uses Shoalwater Bay Training Area (SWBTA) as a research example to examine environmental management strategies conducted by the ADF. SWBTA is one of the most significant Defence training areas in Australia, with a large number of single, joint and combined military exercises conducted in the area. With its maritime component contained in the Great Barrier Reef Marine Park (GBRMP), the Great Barrier Reef World Heritage Area (GBRWHA), and abutting Queensland’s State Marine Parks, it has high protection values. It is therefore vital for the ADF to adopt environmentally responsible management while they are conducting military activities. As to various tools employed to manage environmental performance, the ISO 14001 Environmental Management System (EMS) is widely used by the ADF. This paper examines military activities and marine environmental management within SWBTA, using the Talisman Saber (TS) exercise series as an example. These are extensive joint exercises conducted by the ADF and the United States defence forces. The paper outlines relevant legislative framework and environmental policies, analyses how the EMS operates in environmental management of military activities, and how military activities comply with these regulations. It discusses the implementation of the ADF EMS, including risk reduction measures, environmental awareness training, consultation and communication with stakeholders. A number of environmental management actions used in the TS exercises are presented to demonstrate the EMS application. Our investigations to this point indicate that the ADF is
Full Text Available Generalist predation constitutes a driving force for the evolution of chemical defences. In the Antarctic benthos, asteroids and omnivore amphipods are keystone opportunistic predators. Sessile organisms are therefore expected to develop defensive mechanisms mainly against such consumers. However, the different habits characterizing each predator may promote variable responses in prey. Feeding-deterrence experiments were performed with the circumpolar asteroid macropredator Odontaster validus to evaluate the presence of defences within the apolar lipophilic fraction of Antarctic invertebrates and macroalgae. A total of 51% of the extracts were repellent, yielding a proportion of 17 defended species out of the 31 assessed. These results are compared with a previous study in which the same fractions were offered to the abundant circum-Antarctic amphipod Cheirimedon femoratus. Overall, less deterrence was reported towards asteroids (51% than against amphipods (80.8%, principally in sponge and algal extracts. Generalist amphipods, which establish casual host–prey sedentary associations with biosubstrata (preferentially sponges and macroalgae, may exert more localized predation pressure than sea stars on certain sessile prey, which would partly explain these results. The nutritional quality of prey may interact with feeding deterrents, whose production is presumed to be metabolically expensive. Although optimal defence theory posits that chemical defences are managed and distributed as to guarantee protection at the lowest cost, we found that only a few organisms localized feeding deterrents towards most exposed and/or valuable body regions. Lipophilic defensive metabolites are broadly produced in Antarctic communities to deter opportunistic predators, although several species combine different defensive traits.
Lan, Z.Y.; Krosse, S.; Achard, P.; Van Dam, N.M.; Bede, J.C.
Upon insect herbivory, many plant species change the direction of metabolic flux from growth into defence. Two key pathways modulating these processes are the gibberellin (GA)/DELLA pathway and the jasmonate pathway. In this study, the effect of caterpillar herbivory on plant-induced responses was compared between wild-type Arabidopsis thaliana (L.) Heynh. and quad-della mutants that have constitutively elevated GA responses. The labial saliva (LS) of caterpillars of the beet armyworm, Spodop...
Juan-Luis GOMEZ COLOMER
Although the designated topic for discussion is the technical right to a defence in Spain, I consider it opportune to give a brief overview of the current criminal procedural situation in my country. Spain is a young democracy of only 35 years in which sovereignty was returned to the people with the 1978 constitution, the moment that marked the beginning of a period during which we have enjoyed the full range of freedoms.
Lawson, Daniel John; Rubin-Delanchy, Patrick T G; Heard, Nicholas A.; Adams, Niall M.
How can we effectively use costly statistical models in the defence of large computer networks? Statistical modelling and machine learning are potentially powerful ways to detect threats as they do not require a human level understanding of the attack. However, they are rarely applied in practice as the computational cost of deploying all but the most simple algorithms can become implausibly large. Here we describe a multilevel approach to statistical modelling in which descriptions of the no...
Michael Tyworth; Nicklaus A. Giacobe; Vincent F. Mancuso; Michael. D. McNeese; Hall, David L.
In this paper we argue for a human-in-the-loop approach to the study of situation awareness in computer defence analysis (CDA). The cognitive phenomenon of situation awareness (SA) has received significant attention in cybersecurity/CDA research. Yet little of this work has attended to the cognitive aspects of situation awareness in the CDA context; instead, the human operator has been treated as an abstraction within the larger human-technology system. A more human-centric approach that seek...
Maternal type 1 diabetes is associated with an increased risk for foetal malformations. The mechanism by which diabetes is teratogenic is not fully known. Previous studies have demonstrated that radical oxygen species can contribute to the teratogenicity of glucose and diabetes. The aim of the present work was to study different aspects of free radical damage and antioxidant defence in experimental diabetic pregnancy. The activity of the antioxidant enzyme catalase and the mRNA levels of an...
Ravindra Kumar; Manoj Kumar Misra; Rohitash Kumar; Deepak Gupta; P. K. Khatri; B. B. Tak; S. R. Meena
Phase change materials (PCM) are being utilised world over for energy storage and temperature smoothening applications. Defence Laboratory Jodhpur (DLJ) has initiated a R&D programme to apply PCM in solving many heat related problems being faced by Indian forces during desert operations specially failure of mission-critical components. Under the programme, special organic PCM (Patent application no. 2258/DEL/2007 and low melting metal alloys have been developed well tuned to desert diurna...
Pasteels, Jacques M.; Rowell-Rahier, Martine; Braekman Jean-Claude; Daloze, Désiré
The chemical defences of the Chrysomelinae are reviewed. Defensive glandular secretions have evolved independently in larvae and adults, and faster than the morphology of the glands. Both characters are used in a phylogenetic study of the Chrysomelini, disclosing suprageneric affinities. First, a close relationship between the Chrysomelina and Phratora is proposed. Secondly, Leptinotarsa and Gonioctena are probably more closely related to the Chrysolinina than to the Chrysomelina and Phratora...
Reynolds, David; Chapman, Christopher; Kelly, Anthony; Muijs, Daniel; Sammons, Pamela
Educational effectiveness research (EER) has made a significant contribution to our understanding of the characteristics and processes associated with more and less effective schools in a diverse range of contexts. However, this remains a contested field of inquiry and has been subjected to significant critique. This paper examines the origins and development of EER and summarises the key critiques and defences of the field during the past 30 years. It then moves on to examine the recent crit...
Farace, Giovanni; Fernandez, Olivier; Jacquens, Lucile; Coutte, François; Krier, François; Jacques, Philippe; Clément, Christophe; Barka, Essaid Ait; Jacquard, Cédric; Dorey, Stéphan
Non-self-recognition of microorganisms partly relies on the perception of microbe-associated molecular patterns (MAMPs) and leads to the activation of an innate immune response. Bacillus subtilis produces three main families of cyclic lipopeptides (LPs), namely surfactins, iturins and fengycins. Although LPs are involved in induced systemic resistance (ISR) activation, little is known about defence responses induced by these molecules and their involvement in local resistance to fungi. Here, we showed that purified surfactin, mycosubtilin (iturin family) and plipastatin (fengycin family) are perceived by grapevine plant cells. Although surfactin and mycosubtilin stimulated grapevine innate immune responses, they differentially activated early signalling pathways and defence gene expression. By contrast, plipastatin perception by grapevine cells only resulted in early signalling activation. Gene expression analysis suggested that mycosubtilin activated salicylic acid (SA) and jasmonic acid (JA) signalling pathways, whereas surfactin mainly induced an SA-regulated response. Although mycosubtilin and plipastatin displayed direct antifungal activity, only surfactin and mycosubtilin treatments resulted in a local long-lasting enhanced tolerance to the necrotrophic fungus Botrytis cinerea in grapevine leaves. Moreover, challenge with specific strains overproducing surfactin and mycosubtilin led to a slightly enhanced stimulation of the defence response compared with the LP-non-producing strain of B. subtilis. Altogether, our results provide the first comprehensive view of the involvement of LPs from B. subtilis in grapevine plant defence and local resistance against the necrotrophic pathogen Bo. cinerea. Moreover, this work is the first to highlight the ability of mycosubtilin to trigger an immune response in plants. PMID:25040001
The Flood and Coastal Defence (FCD) project of the United Kingdom Foresight Programme was involved a scenario exercise that has been very influential on UK policy. The scenario approach had an extensive prehistory, and its use in a water management context predates FCD. It continues to evolve and influence decision-making in many fields. This study presents an overview of the approach and how it has come to be so influential. The FCD project features by an integrated scenario analysis of the ...
Al-Baharna, Marwa M.; Whitford, David L
Objectives: Primary care audits in Bahrain have consistently revealed a failure to meet recognised standards of delivery of process and outcome measures to patients with diabetes. This study aimed to establish for the first time the quality of diabetes care in a Bahraini hospital setting. Methods: A retrospective clinical audit was conducted of a random sample of patients attending the Diabetes and Endocrine Center at the Bahrain Defence Forces Hospital over a 15-month period which ended in J...
Schuijt, T. J.; Lankelma, J.M.; Scicluna, B.P.; Melo, E; Roelofs, J.J.; Boer, de, J.W.; Hoogendijk, A.J.; Beer, de, VHJ Vincent; De Vos; Belzer, C.; Poll, van der, T.; Wiersinga, W.J.
OBJECTIVE: Pneumonia accounts for more deaths than any other infectious disease worldwide. The intestinal microbiota supports local mucosal immunity and is increasingly recognised as an important modulator of the systemic immune system. The precise role of the gut microbiota in bacterial pneumonia, however, is unknown. Here, we investigate the function of the gut microbiota in the host defence against Streptococcus pneumoniae infections. DESIGN: We depleted the gut microbiota in C57BL/6 mice ...
Offsets have taken centre stage in defence trade. To date, more than 78 countries around the world practice offsets and outstanding offsets obligations run into billions of US dollars However, why have offsets gained such a momentum? Increasingly, both sellers and buyers in the arms trade view offsets as an efficient and effective economic compensation tool to justify arms deals. Buyers, consider offsets as a catalyst for industrial and technological development, employment, cr...
Juan-Luis GOMEZ COLOMER
Full Text Available Although the designated topic for discussion is the technical right to a defence in Spain, I consider it opportune to give a brief overview of the current criminal procedural situation in my country. Spain is a young democracy of only 35 years in which sovereignty was returned to the people with the 1978 constitution, the moment that marked the beginning of a period during which we have enjoyed the full range of freedoms.
Vaughan, Martha M; Huffaker, Alisa; Schmelz, Eric A.; Dafoe, Nicole J; Christensen, Shawn; Sims, James; Martins, Vitor F; Swerbilow, Jay; Romero, Maritza; Hans T. Alborn; Allen, Leon HARTWELL; Teal, Peter EA
Maize is by quantity the most important C4 cereal crop; however, future climate changes are expected to increase maize susceptibility to mycotoxigenic fungal pathogens and reduce productivity. While rising atmospheric [CO2] is a driving force behind the warmer temperatures and drought, which aggravate fungal disease and mycotoxin accumulation, our understanding of how elevated [CO2] will effect maize defences against such pathogens is limited. Here we report that elevated [CO2] increases maiz...
Alsdurf, Jacob D; Ripley, Tayler J; Matzner, Steven L; Siemens, David H
Areas just across species range boundaries are often stressful, but even with ample genetic variation within and among range-margin populations, adaptation towards stress tolerance across range boundaries often does not occur. Adaptive trans-generational plasticity should allow organisms to circumvent these problems for temporary range expansion; however, range boundaries often persist. To investigate this dilemma, we drought stressed a parent generation of Boechera stricta (A.Gray) A. Löve & D. Löve, a perennial wild relative of Arabidopsis, representing genetic variation within and among several low-elevation range margin populations. Boechera stricta is restricted to higher, moister elevations in temperate regions where generalist herbivores are often less common. Previous reports indicate a negative genetic correlation (genetic tradeoff) between chemical defence allocation and abiotic stress tolerance that may prevent the simultaneous evolution of defence and drought tolerance that would be needed for range expansion. In growth chamber experiments, the genetic tradeoff became undetectable among offspring sib-families whose parents had been drought treated, suggesting that the stress-induced trans-generational plasticity may circumvent the genetic tradeoff and thus enable range expansion. However, the trans-generational effects also included a conflict between plastic responses (environmental tradeoff); offspring whose parents were drought treated were more drought tolerant, but had lower levels of glucosinolate toxins that function in defence against generalist herbivores. We suggest that either the genetic or environmental tradeoff between defence allocation and stress tolerance has the potential to contribute to range limit development in upland mustards. PMID:24307931
Boddy, Amy M; Kokko, Hanna; Breden, Felix; Wilkinson, Gerald S; Aktipis, C Athena
The factors influencing cancer susceptibility and why it varies across species are major open questions in the field of cancer biology. One underexplored source of variation in cancer susceptibility may arise from trade-offs between reproductive competitiveness (e.g. sexually selected traits, earlier reproduction and higher fertility) and cancer defence. We build a model that contrasts the probabilistic onset of cancer with other, extrinsic causes of mortality and use it to predict that intense reproductive competition will lower cancer defences and increase cancer incidence. We explore the trade-off between cancer defences and intraspecific competition across different extrinsic mortality conditions and different levels of trade-off intensity, and find the largest effect of competition on cancer in species where low extrinsic mortality combines with strong trade-offs. In such species, selection to delay cancer and selection to outcompete conspecifics are both strong, and the latter conflicts with the former. We discuss evidence for the assumed trade-off between reproductive competitiveness and cancer susceptibility. Sexually selected traits such as ornaments or large body size require high levels of cell proliferation and appear to be associated with greater cancer susceptibility. Similar associations exist for female traits such as continuous egg-laying in domestic hens and earlier reproductive maturity. Trade-offs between reproduction and cancer defences may be instantiated by a variety of mechanisms, including higher levels of growth factors and hormones, less efficient cell-cycle control and less DNA repair, or simply a larger number of cell divisions (relevant when reproductive success requires large body size or rapid reproductive cycles). These mechanisms can affect intra- and interspecific variation in cancer susceptibility arising from rapid cell proliferation during reproductive maturation, intrasexual competition and reproduction. PMID:26056364
Gupta, Santosh Kumar; Rai, Amit Kumar; Kanwar, Shamsher Singh; Chand, Duni; Singh, Nagendera Kumar; Sharma, Tilak Raj
The Pi54 gene (Pi-k(h)) confers a high degree of resistance to diverse strains of the fungus Magnaporthe oryzae. In order to understand the genome-wide co-expression of genes in the transgenic rice plant Taipei 309 (TP) containing the Pi54 gene, microarray analysis was performed at 72 h post-inoculation of the M. oryzae strain PLP-1. A total of 1154 differentially expressing genes were identified in TP-Pi54 plants. Of these, 587 were up-regulated, whereas 567 genes were found to be down-regulated. 107 genes were found that were exclusively up-regulated and 58 genes that were down- regulated in the case of TP-Pi54. Various defence response genes, such as callose, laccase, PAL, and peroxidase, and genes related to transcription factors like NAC6, Dof zinc finger, MAD box, bZIP, and WRKY were found to be up-regulated in the transgenic line. The enzymatic activities of six plant defence response enzymes, such as peroxidase, polyphenol oxidase, phenylalanine ammonia lyase, β-glucosidase, β-1,3-glucanase, and chitinase, were found to be significantly high in TP-Pi54 at different stages of inoculation by M. oryzae. The total phenol content also increased significantly in resistant transgenic plants after pathogen inoculation. This study suggests the activation of defence response and transcription factor-related genes and a higher expression of key enzymes involved in the defence response pathway in the rice line TP-Pi54, thus leading to incompatible host-pathogen interaction. PMID:22058403
Petit, Anne Noelle; Vaillant-Gaveau, Nathalie; Walker, Anne Sophie; Leroux, Pierre; Baillieul, Fabienne; Panon, Marie-Laure; Clément, Christophe; Fontaine, Florence
Botrytis bunch rot of grapes is mainly controlled by applying fungicides at three crop stages: the end of flowering (BBCH 68), bunch closure (BBCH 77) and the beginning of veraison (BBCH 81). The phenylpyrroles derivative fludioxonil is among the most effective fungicides registered to control Botrytis cinerea. Its effectiveness was investigated in relation to spray timing, fungicide resistance and defence responses of grapevine. Frequencies of B. cinerea strains which were resistant to fungi...
Conceição, Luís F. R.; Franklin, Gregory; Ribeiro, Catarina; Dias, Alberto Carlos Pires
To elucidate the defence mechanisms of Hypericum perforatum L. against Colletotrichum gloeosporioides, we utilized cell suspension cultures. When primed with methyl jasmonate, H. perforatum cells showed a double oxidative burst upon Colletotrichum gloeosporioides elicitation typical of a hypersensitive response. Phenolic profile of the cells was modified upon various stimuli such as salicylic acid, MeJ and C. gloeosporioides. The possible importance of reactive oxygen species production an...
Romero Rojo, Francisco Javier; Roy, Rajkumar; Shehab, Essam; Wardle, P. J.
The aerospace and defence industries are moving towards new types of agreement such as availability contracts based on Product-Service System (PSS) business models. Obsolescence has become one of the main problems that will impact on many areas of the system during its life cycle. This paper presents the major challenges to managing obsolescence for availability contracts, identified by means of a comprehensive literature review and several interviews and forums with experts in ob...
Bjork, Adam; Starmer, William T.; Higginson, Dawn M.; Rhodes, Christopher J.; Pitnick, Scott
Postcopulatory sexual selection favours males which are strong offensive and defensive sperm competitors. As a means of identifying component traits comprising each strategy, we used an experimental evolution approach. Separate populations of Drosophila melanogaster were selected for enhanced sperm offence and defence. Despite using a large outbred population and evidence of substantive genetic variation for each strategy, neither trait responded to selection in the two replicates of this exp...
Increased literary attention and debate has been directed at business turnaround in recent years; albeit as Furman & McGahan (2002, p.238) suggest; ‘despite their centrality, little is still known about their prevalence or trajectory’. This case study departs from most other turnaround research by addressing the global Aerospace and Defence sector; of which has remained unexplored until this point. Specifically, it looks to ascertain ‘how new top management enact successful turnaround’ and co...
Monique F. Crane; Virginia Lewis; Andrew Cohn; Hodson, Stephanie E.; Ruth Parslow; Bryant, Richard A; Cate Chesney; David Forbes
In the last two decades there has been increasing attention directed at the analysis of psychological resilience. The number of modern-day veterans returning from Iraq and Afghanistan has sparked great interest in identifying mechanisms that can either erode or facilitate psychological resilience. In November 2009, the Australian Defence Force (ADF) in collaboration with the Australian Centre for Post-traumatic Mental Health (ACPMH) launched a longitudinal study of psychological resilience du...
Although in the last 10 years in Italy there has been a greater sensitivity by the legislature to the trafficking, including in relation to international commitments such as the Palermo Protocol, there are still difficulties and deficiencies in affording effective jurisdictional protection for victims of this shameful social phenomenon. Italy has started to pay a sensitive normative attention to the defence of the victims of trafficking through the art. 18 of the DLvo 286/98I that stipulates ...
Kammerhofer, N.; Radakovic, Z.; Regis, J.M.A.; Dobrev, P.; Vaňková, R. (Radomíra); Grundler, F. M. W.; Siddique, S.; Hofmann, J.; Wieczorek, K.
Heterodera schachtii, a plant-parasitic cyst nematode, invades host roots and induces a specific syncytial feeding structure, from which it withdraws all required nutrients, causing severe yield losses. The system H. schachtii–Arabidopsis is an excellent research model for investigating plant defence mechanisms. Such responses are suppressed in well-established syncytia, whereas they are induced during early parasitism. However, the mechanisms by which the defence responses are modulated and ...
Stynoski, Jennifer L.; Shelton, Georgia; Stynoski, Peter
Parents defend their young in many ways, including provisioning chemical defences. Recent work in a poison frog system offers the first example of an animal that provisions its young with alkaloids after hatching or birth rather than before. But it is not yet known whether maternally derived alkaloids are an effective defence against offspring predators. We identified the predators of Oophaga pumilio tadpoles and conducted laboratory and field choice tests to determine whether predators are d...
Castex, Mathieu; Lemaire, Pierrette; Wabete, Nelly; Chim, Liet
Antioxidant defences and induced oxidative stress tissue damage of the blue shrimp Litopenaeus stylirostris, under challenge with Vibrio nigriputchritudo, were investigated for a 72-h period. For this purpose, L stylirostris were first infected by immersion with pathogenic V. nigripulchritudo strain SFn1 and then antioxidant defences: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (Gpx), Total antioxidant status (TAS), glutathiones and induced tissue damage (MDA and carbon...
L Bowden; NM Dheilly; DA Raftos; SV Nair
Our understanding of invertebrate immune systems is undergoing a paradigm shift. Until recently, the host defence responses of invertebrates were thought to rely on limited molecular diversity that could not tailor reactions toward specific microbes. This view is now being challenged. Highly discriminatory defence responses, and hypervariable gene systems with the potential to drive them, have been identified in a number of invertebrate groups. These systems seem to be quite distinct, suggest...
Nicot, Philippe; Bardin, Marc; Debruyne, François; Duffaud, Magali; Lecompte, François; Neu, Laurent; Pascal, Michel
Although Nitrogen (N) is a key component in many compounds implicated in host-pathogen interactions, little is known on the possible effect of N fertilisation of the plant on the efficacy of defence-stimulating biocontrol agents. In the present work we examined the effect of five levels of N nutrition on the susceptibility of strawberry leaves to Botrytis cinerea and on the protective efficacy of two biocontrol products presumed to induce plant defence mechanisms. Two days after the app...
Plant and herbivores coexist for millions of years and have developed an arsenal of complex interactions. They can be mutually beneficial or antagonistic. In antagonistic interaction, plants have evolved a wide array of constitutive morphological, biochemical and molecular defences to defend themselves from herbivore attacks (Karban and Baldwin, 1997; Walling, 2000). In addition, plants can activate induced direct defences that often act systemically throughout the plant and are typically eff...
Full Text Available Chemical defences represent a main trait of the plant innate immune system. Besides regulating the relationship between plants and their ecosystems, phytochemicals are involved both in resistance against pathogens and in tolerance towards abiotic stresses, such as atmospheric pollution. Plant defence metabolites arise from the main secondary metabolic routes, the phenylpropanoid, the isoprenoid and the alkaloid pathways. In plants, antibiotic compounds can be both preformed (phytoanticipins and inducible (phytoalexins, the former including saponins, cyanogenic glycosides and glucosinolates. Chronic exposure to tropospheric ozone (O3 stimulates the carbon fluxes from the primary to the secondary metabolic pathways to a great extent, inducing a shift of the available resources in favour of the synthesis of secondary products. In some cases, the plant defence responses against pathogens and environmental pollutants may overlap, leading to the unspecific synthesis of similar molecules, such as phenylpropanoids. Exposure to ozone can also modify the pattern of biogenic volatile organic compounds (BVOC, emitted from plant in response to herbivore feeding, thus altering the tritrophic interaction among plant, phytophagy and their natural enemies. Finally, the synthesis of ethylene and polyamines can be regulated by ozone at level of S-adenosylmethionine (SAM, the biosynthetic precursor of both classes of hormones, which can, therefore, mutually inhibit their own biosynthesis with consequence on plant phenotype.
S. Thamarai Selvi
Full Text Available This paper proposes a solution methodology for a missile defence problem using theatremissile defence (TMD concept. In the missile defence scenario, the concept of TMD is generallyused for the optimal allocation of interceptors to counter the attack missiles. The problem iscomputationally complex due to the presence of enormous state space. The Learning vectorquantiser–Radial basis function (LVQ-RBF multi-agent hybrid neural architecture is used as thelearning structure, and Q-learning as the learning method. The LVQ-RBF multi-agent hybridneural architecture overcomes the complex state space issue using the partitioning and weightedlearning approach. The proposed LVQ-RBF multi- agent hybrid architecture improvises thelearning performance by the local and global error criterion. The state space is explored withinitial coarse partitioning by LVQ neural network. The fine partitioning of the state space isperformed using the multi-agent RBF neural network. The discrete reward scheme is used forLVQ-RBF multi-agent hybrid neural architecture. It has a hierarchical architecture which enablesquicker convergence without the loss of accuracy. The simulation of the TMD is performed with500 assets and six priority of assets.
Tamiru, Muluneh; Takagi, Hiroki; Abe, Akira; Yokota, Takao; Kanzaki, Hiroyuki; Okamoto, Haruko; Saitoh, Hiromasa; Takahashi, Hideyuki; Fujisaki, Koki; Oikawa, Kaori; Uemura, Aiko; Natsume, Satoshi; Jikumaru, Yusuke; Matsuura, Hideyuki; Umemura, Kenji; Terry, Matthew J; Terauchi, Ryohei
Understanding how plants allocate their resources to growth or defence is of long-term importance to the development of new and improved varieties of different crops. Using molecular genetics, plant physiology, hormone analysis and Next-Generation Sequencing (NGS)-based transcript profiling, we have isolated and characterized the rice (Oryza sativa) LESION AND LAMINA BENDING (LLB) gene that encodes a chloroplast-targeted putative leucine carboxyl methyltransferase. Loss of LLB function results in reduced growth and yield, hypersensitive response (HR)-like lesions, accumulation of the antimicrobial compounds momilactones and phytocassanes, and constitutive expression of pathogenesis-related genes. Consistent with these defence-associated responses, llb shows enhanced resistance to rice blast (Magnaporthe oryzae) and bacterial blight (Xanthomonas oryzae pv. oryzae). The lesion and resistance phenotypes are likely to be caused by the over-accumulation of jasmonates (JAs) in the llb mutant including the JA precursor 12-oxo-phytodienoic acid. Additionally, llb shows an increased lamina inclination and enhanced early seedling growth due to elevated brassinosteroid (BR) synthesis and/or signalling. These findings show that LLB functions in the chloroplast to either directly or indirectly repress both JA- and BR-mediated responses, revealing a possible mechanism for controlling how plants allocate resources for defence and growth. PMID:26864209
Individual monitoring has always played an important role in radiological protection. There is continuous development in the field of dosimetry systems and many changes have taken place in last many years. The use of radiation for peaceful purposes is increasing with advancement of technological growth in the country. Thermo luminescence dosimeters (TLDs) have emerged as one of the best alternatives for personal monitoring. Defence sector has nearly 2100 persons, who are working in various Military Hospitals, Military Colleges, DRDO Labs, Defence Ordinance factories and many others CPMFs like CISF, BSF, who are likely to receive radiation doses. Defence Laboratory, Jodhpur is providing the TLD personal monitoring service since Jan 1999 as per the guideline by B.A.R.C. to all the institutions mentioned above. This paper brings out salient features of this service in terms of facility available, procedures fulfilling the requirement of accreditation, over exposure reported, quality measures adopted and quality assurance results conducted by BARC, utility and suggestions for such type of services. (author)
As part of the revision of United States Department of Energy (DOE) Order 5820.2, Chapter III, a process for developing a site specific low level radioactive waste (LLW) classification system for DOE defence LLW is being considered. Waste classification is a mechanism that can help ensure that overall performance objectives established to protect public health and ensure public safety will be met. The DOE follows the guidance of the National Council on Radiation Protection and Measurements (NCRP) to the fullest extent practicable with respect to radiation protection standards. The NCRP endorses most of the recommendations of the International Commission on Radiological Protection (ICRP). Thus, the DOE has adopted ICRP 30 and ICRP 48 as the basis for all internal dose calculations. For LLW management practices, the DOE is requiring equivalence with US Nuclear Regulatory Commission (NRC) requirements. However, system-wide classification will be less practical for the DOE than the NRC because of dissimilarities of waste mixtures and disposal methods between DOE sites. Site specific waste stream characterization, source term determination and radiological performance assessment will be required for DOE disposal facilities to determine the maximum disposal capacity and the most efficient disposal practices for defence LLW. This process will also demonstrate compliance with the overall performance objectives, thus providing the public health and safety. The paper discusses the procedure that the DOE is considering in the development of a site and waste specific LLW classification system for DOE defence wastes. (author). 10 refs, 1 tab
Levasseur, Anthony; Bekliz, Meriem; Chabrière, Eric; Pontarotti, Pierre; La Scola, Bernard; Raoult, Didier
Since their discovery, giant viruses have revealed several unique features that challenge the conventional definition of a virus, such as their large and complex genomes, their infection by virophages and their presence of transferable short element transpovirons. Here we investigate the sensitivity of mimivirus to virophage infection in a collection of 59 viral strains and demonstrate lineage specificity in the resistance of mimivirus to Zamilon, a unique virophage that can infect lineages B and C of mimivirus but not lineage A. We hypothesized that mimiviruses harbour a defence mechanism resembling the clustered regularly interspaced short palindromic repeat (CRISPR)-Cas system that is widely present in bacteria and archaea. We performed de novo sequencing of 45 new mimivirus strains and searched for sequences specific to Zamilon in a total of 60 mimivirus genomes. We found that lineage A strains are resistant to Zamilon and contain the insertion of a repeated Zamilon sequence within an operon, here named the 'mimivirus virophage resistance element' (MIMIVIRE). Further analyses of the surrounding sequences showed that this locus is reminiscent of a defence mechanism related to the CRISPR-Cas system. Silencing the repeated sequence and the MIMIVIRE genes restores mimivirus susceptibility to Zamilon. The MIMIVIRE proteins possess the typical functions (nuclease and helicase) involved in the degradation of foreign nucleic acids. The viral defence system, MIMIVIRE, represents a nucleic-acid-based immunity against virophage infection. PMID:26934229
Shui, Jr-Wen; Larange, Alexandre; Kim, Gisen; Vela, Jose Luis; Zahner, Sonja; Cheroutre, Hilde; Kronenberg, Mitchell
The herpes virus entry mediator (HVEM), a member of the tumour-necrosis factor receptor family, has diverse functions, augmenting or inhibiting the immune response. HVEM was recently reported as a colitis risk locus in patients, and in a mouse model of colitis we demonstrated an anti-inflammatory role for HVEM, but its mechanism of action in the mucosal immune system was unknown. Here we report an important role for epithelial HVEM in innate mucosal defence against pathogenic bacteria. HVEM enhances immune responses by NF-κB-inducing kinase-dependent Stat3 activation, which promotes the epithelial expression of genes important for immunity. During intestinal Citrobacter rodentium infection, a mouse model for enteropathogenic Escherichia coli infection, Hvem−/− mice showed decreased Stat3 activation, impaired responses in the colon, higher bacterial burdens and increased mortality. We identified the immunoglobulin superfamily molecule CD160 (refs 7 and 8), expressed predominantly by innate-like intraepithelial lymphocytes, as the ligand engaging epithelial HVEM for host protection. Likewise, in pulmonary Streptococcus pneumoniae infection, HVEM is also required for host defence. Our results pinpoint HVEM as an important orchestrator of mucosal immunity, integrating signals from innate lymphocytes to induce optimal epithelial Stat3 activation, which indicates that targeting HVEM with agonists could improve host defence. PMID:22801499
Dutertre, Sébastien; Jin, Ai-Hua; Vetter, Irina; Hamilton, Brett; Sunagar, Kartik; Lavergne, Vincent; Dutertre, Valentin; Fry, Bryan G; Antunes, Agostinho; Venter, Deon J; Alewood, Paul F; Lewis, Richard J
Venomous animals are thought to inject the same combination of toxins for both predation and defence, presumably exploiting conserved target pharmacology across prey and predators. Remarkably, cone snails can rapidly switch between distinct venoms in response to predatory or defensive stimuli. Here, we show that the defence-evoked venom of Conus geographus contains high levels of paralytic toxins that potently block neuromuscular receptors, consistent with its lethal effects on humans. In contrast, C. geographus predation-evoked venom contains prey-specific toxins mostly inactive at human targets. Predation- and defence-evoked venoms originate from the distal and proximal regions of the venom duct, respectively, explaining how different stimuli can generate two distinct venoms. A specialized defensive envenomation strategy is widely evolved across worm, mollusk and fish-hunting cone snails. We propose that defensive toxins, originally evolved in ancestral worm-hunting cone snails to protect against cephalopod and fish predation, have been repurposed in predatory venoms to facilitate diversification to fish and mollusk diets. PMID:24662800
Full Text Available Chemical defences against predators are widespread in the animal kingdom although have been seldom reported in birds. Here, we investigate the possibility that the orange liquid that nestlings of an insectivorous bird, the Eurasian roller (Coracias garrulus, expel when scared at their nests acts as a chemical defence against predators. We studied the diet of nestling rollers and vomit origin, its chemical composition and deterrent effect on a mammal generalist predator. We also hypothesized that nestling rollers, as their main prey (i.e. grasshoppers do from plants, could sequester chemicals from their prey for their use. Grasshoppers, that also regurgitate when facing to a threat, store the harmful substances used by plants to defend themselves against herbivores. We found that nestling rollers only vomit after being grasped and moved. The production of vomit depended on food consumption and the vomit contained two deterrent chemicals (hydroxycinnamic and hydroxybenzoic acids stored by grasshoppers and used by plants to diminish herbivory, suggesting that they originate from the rollers' prey. Finally, we showed for the first time that the oral secretion of a vertebrate had a deterrent effect on a model predator because vomit of nestling rollers made meat distasteful to dogs. These results support the idea that the vomit of nestling rollers is a chemical defence against predators.
Ramos, Tomás B; Alves, Inês; Subtil, Rui; Joanaz de Melo, João
The development of environmental performance policy indicators for public services, and in particular for the defence sector, is an emerging issue. Despite a number of recent initiatives there has been little work done in this area, since the other sectors usually focused on are agriculture, transport, industry, tourism and energy. This type of tool can be an important component for environmental performance evaluation at policy level, when integrated in the general performance assessment system of public missions and activities. The main objective of this research was to develop environmental performance policy indicators for the public sector, specifically applied to the defence sector. Previous research included an assessment of the environmental profile, through the evaluation of how environmental management practices have been adopted in this sector and an assessment of environmental aspects and impacts. This paper builds upon that previous research, developing an indicator framework--SEPI--supported by the selection and construction of environmental performance indicators. Another aim is to discuss how the current environmental indicator framework can be integrated into overall performance management. The Portuguese defence sector is presented and the usefulness of this methodology demonstrated. Feasibility and relevancy criteria are applied to evaluate the set of indicators proposed, allowing indicators to be scored and indicators for the policy level to be obtained. PMID:16580128
Research for civil defence and disaster control 1975-1985. Festschrift on the occasion of the 65th anniversary of Paul Wilhelm Kolb on August 16, 1985. Forschungen fuer den Zivil- und Katastrophenschutz 1975-1985. Festschrift fuer Paul Wilhelm Kolb zum 65. Geburtstag am 16. August 1985
The Civil Defence Commission belongs to the Ministry of the Interior, its expert members advising the Ministry 'on all matters concerning the protection of the civilian population in the case of disaster or defence'. Apart from collecting and evaluating relevant information, the Commission carries out experimental and theoretical research on special topics. The Commission consists of eight sub-divisions and presently counts about 150 members. The publication in hand reports on the achievements and activities of the Commission over the last decade. The technical contributions are concerned with: Protection by shelters and other buildings; radioactive fallout; radiation doses and effects; radiation damage and disease; medical service in the case of disaster; pharmacology, toxicology and body protection; epidemiology; psychobiology and behaviour under stress. (orig./HSCH).
Walker, W A
An important adaptation of the gastrointestinal tract to the extrauterine environment is its development of a mucosal barrier against the penetration of harmful substances (bacteria, toxins and antigens) present within the intestinal lumen. At birth, the newborn infant must be prepared to deal with bacterial colonization of the gut, with formation of toxic byproducts of bacteria and viruses (enterotoxins and endotoxins) and with the ingestion of antigens (milk proteins). These potentially noxious substances if allowed to penetrate the mucosal epithelial barrier under pathological conditions can cause inflammatory and allergic reactions which may result in gastrointestinal and systemic disease states. To combat the potential danger of invasion across the mucosal barrier the infant must develop an elaborate system of defence mechanisms within the lumen and on the luminal mucosal surface which act to control and maintain the epithelium as an impermeable barrier to uptake of macromolecular antigens. These defences include a unique immunological system adapted to function in the complicated milieu of the intestine as well as other non-immunological processes such as a gastric barrier, intestinal surface secretions, peristaltic movement and natural antibacterial substances (lysozyme, bile salts) which also help to provide maximum protection for the intestinal surface. Unfortunately, during the immediate postpartum period, particularly for premature and small-for-dates infants, this elaborate local defence system is incompletely developed. As a result of the delay in the maturation of the mucosal barrier newborn infants are particularly vulnerable to pathological penetration by harmful intraluminal substances. The consequences of altered defence are susceptibility to infection and the potential for hypersensitivity reactions and for formation of immune complexes. With these reactions comes the potential for developing life-threatening diseases such as necrotizing
Muñoz-Izquierdo, Nora; Gil-Gómez de Liaño, Beatriz; Rin-Sánchez, Francisco Daniel; Pascual-Ezama, David
Based on an experiment conducted with undergraduate students from three different majors (business economics, psychology and engineering), we study the relationship between honesty and altruism. We asked participants to toss a coin with a black and a white side. Participants won a chocolate if they reported the white outcome, whereas no gift was given if they reported black. It was done privately, so they could decide whether or not to cheat. Reporting the prize-losing side (that is, being ho...
Bolle, Friedel; Kritikos, Alexander S.
Models to the issue of altruism which rely on externalities of well-being are rarely used explicitly. In this paper we compare such utility-based approaches with the standard approach on altruism which is based on externalities of income. Testable differences of both types of models are derived in the case of incomplete information. More specifically, applied to the Dictator Game and the Impunity Game both played under incomplete information, the utility-based based approach predicts dictator...
Schubert, Mario; Bleuler-Martinez, Silvia; Butschi, Alex; Wälti, Martin A.; Egloff, Pascal; Stutz, Katrin; Yan, Shi; Wilson, Iain B. H.; Hengartner, Michael O.; Aebi, Markus; Allain, Frédéric H-T; Künzler, Markus
Discrimination between self and non-self is a prerequisite for any defence mechanism; in innate defence, this discrimination is often mediated by lectins recognizing non-self carbohydrate structures and so relies on an arsenal of host lectins with different specificities towards target organism carbohydrate structures. Recently, cytoplasmic lectins isolated from fungal fruiting bodies have been shown to play a role in the defence of multicellular fungi against predators and parasites. Here, w...
Research of retailer buying behaviour has previously focused on the buying decision. In this paper a new approach to studying retailer buying behaviour is suggested, one which focuses on the sensemaking processes leading up to a decision being made. A research project taking a sensemaking perspec...... perspective is outlined and the implications and expected contribution of studying retailer buying behaviour from a sensemaking perspective are discussed....
Nutrition, neurotoxicants and aggressive behaviour Antisocial behaviour, such as violence, is explained not only by the social environment, as was long believed. Also nutrients and neurotoxicants might play a role. Whether this is the case was studied in this thesis. In two empirical studies possible relations between nutrients and behaviour were investigated. In the first study, levels of nutrients in blood samples of forensic psychiatric patients were measured. Low levels of omega-3 fatty a...
Sempruch, C; Goławska, S; Osiński, P; Leszczyński, B; Czerniewicz, P; Sytykiewicz, H; Matok, H
The study aimed to quantify the influence of common plant polyamines and tyramine on probing behaviour in the bird cherry-oat aphid (Rhopalosiphum padi L.). Electrical penetration graphs (DC) were used to monitor the probing and feeding behaviour of R. padi exposed to the amines agmatine, cadaverine, putrescine, spermidine, spermine and tyramine. The study results showed that the analyzed amines tended to shorten the stylet activity of aphids in the gels (as indicated by the g-C pattern), prolong the duration of non-probing behaviour (g-np pattern) and decrease salivation into the gels (g-E1pattern) and ingestion from the gels (g-G pattern). The 10 mM concentration of the studied amines, especially cadaverine, reduced or completely inhibited aphid ingestion. The obtained results demonstrate that plant amines participate in plant defence responses to R. padi through disturbance of its probing behaviour and the intensity of such effects is concentration dependent. PMID:26898153
Nevada is at the centre of public policy debate with regards to high and low level radioactive waste disposal. Nevada's Yucca Mountain is the only site under consideration for a US geologic repository for commercial spent nuclear fuel and defence high level waste. The Nevada Test Site (NTS) has long been a low level waste (LLW) disposal facility for the Department of Energy (DOE) defence waste and is now expected to take even more LLW as the preferred site for a regional or centralised disposal facility. Furthermore, the primary mission at NTS, defence, continues to add more contamination to the site. Combined, these facts present a public policy enigma, confused further by the intentional separation of the programs by DOE, even though all are essentially conducted at the same site. Involving the public in policy decisions for these programs is a dilemma because the public does not make the same artificial distinctions between them as DOE, DOE credibility suffers from past public involvement efforts conducted during an era of Cold War secrecy and because DOE public involvement programs are operated independently, with little or no co-operation between programs. The public does not know where it fits into the DOE decision-making process or if it impacts the policy decisions being made that affect it. This paper examines the complex maze of radioactive policy and bureaucracy in order to unveil the enigma Nevada residents face. Are they able to navigate this maze to effectively participate in government policy and decision-making? Or, will they remain confused by the government bureaucracy which deliberately makes a mess of the situation and seeks to exploit a politically weak state with large tracts of federally controlled land? lt further evaluates the effect this enigma has in producing acceptable public policy for radioactive waste disposal in the US, the role of public participation in that policy, and the reason the public is disillusioned and disengaged in the
Luzzatto-Knaan, Tal; Kerem, Zohar; Doron-Faigenboim, Adi; Yedidia, Iris
The defence response of Zantedeschia aethiopica, a natural rhizomatous host of the soft rot bacterium Pectobacterium carotovorum, was studied following the activation of common induced resistance pathways—systemic acquired resistance and induced systemic resistance. Proteomic tools were used, together with in vitro quantification and in situ localization of selected oxidizing enzymes. In total, 527 proteins were analysed by label-free mass spectrometry (MS) and annotated against the National Center for Biotechnology Information (NCBI) nonredundant (nr) protein database of rice (Oryza sativa). Of these, the fore most differentially expressed group comprised 215 proteins that were primed following application of methyl jasmonate (MJ) and subsequent infection with the pathogen. Sixty-five proteins were down-regulated following MJ treatments. The application of benzothiadiazole (BTH) increased the expression of 23 proteins; however, subsequent infection with the pathogen repressed their expression and did not induce priming. The sorting of primed proteins by Gene Ontology protein function category revealed that the primed proteins included nucleic acid-binding proteins, cofactor-binding proteins, ion-binding proteins, transferases, hydrolases and oxidoreductases. In line with the highlighted involvement of oxidoreductases in the defence response, we determined their activities, priming pattern and localization in planta. Increased activities were confined to the area surrounding the pathogen penetration site, associating these enzymes with the induced systemic resistance afforded by the jasmonic acid signalling pathway. The results presented here demonstrate the concerted priming of protein expression following MJ treatment, making it a prominent part of the defence response of Z. aethiopica to P. carotovorum. PMID:24822269
Ian Van der Waag
Full Text Available South Africa was ill prepared for the Second World War. Her war potential was limited and Hitler is reputed to have laughed when the South African declaration came on 6 September 1939. The Permanent and Active Citizen Forces were under strength: the first comprised only 350 officers and some five thousand men. There were a further 122 000 men in the Commandos, of whom only 18 000 were reasonably equipped, and, being rurally based and overwhelmingly Afrikaans, many of these men did not support the war effort. Furthermore, training and training facilities were inadequate, there was a shortage of uniforms and equipment and, like the rest of the British Commonwealth, much of the doctrine had not kept pace with technological developments. This predicament developed over the preceding twenty years. The mechanisation of ground forces and the application of new technology for war contrasted sharply with developments in Europe. Although South Africa had the industrial capacity for the development of armour and mechanised forces, arguments based upon the nature of potential enemy forces, poor infrastructure and terrain inaccessibility combined with government policy and financial stringency resulted in nothing being done. Southern Africa, the focus of South African defence policy, was also thought to be unfavourable for mechanised warfare. Inadequate roads and multifarious geographic features concentrated energy on the development of the air arm for operations in Africa and a system of coastal defences to repel a sea assault, as well as a mix of British and Boer-type infantry supported by field artillery. As a result, an expeditionary force had to be prepared from scratch and the first South Africans to serve in the Second World War only left the country in July 1940. Yet the close relationship between the projected role of the Union Defence Force (UDF and the low priority given to force maintenance and weapons acquisition has been perceived by few
Full Text Available Although the evolution of life has turned oxygen into a vital chemical for aerobic organisms, this element can also have deleterious effects on living systems through the production of oxidative stress. This is a process resulting from an imbalance between the excessive production of Reactive Oxygen Species (ROS and the limited action of antioxidant defences. It is a particularly harmful health risk factor, involved in the development of several chronic human pathologies and believed to play a major role in the ageing process. Consequently aerobic metabolism needs a stringent control of ROS. Water too is essential for life, but some organisms widespread throughout nature have the ability to survive complete desiccation by entering an anhydrobiotic state. The loss of water induces changes in metabolism, cell membrane organization, and molecular composition. In the anhydrobiotic state, high temperatures, high humidity, light exposure, and high oxygen partial pressure negatively affect organism survival and directly influence the time required to reactivate the metabolism after a period of desiccation. These abiotic factors induce damages that are accumulated in proportion to the time spent in the desiccated state, potentially leading to organism death. Oxidative stress seems to be one of the most deleterious damages due to water depletion, therefore anhydrobiosis also needs a stringent control of ROS production. Anhydrobiotic organisms seem to apply two main strategies to cope with the danger of oxygen toxicity, namely an increased efficiency of antioxidant defences and a metabolic control of both energy-production and energy-consuming processes. Experimental studies provide evidence that antioxidant defences such as ROS scavenging enzymes (e.g. peroxidases, catalases, superoxide dismutase, glutathione peroxidases and other molecules (e.g. glutathione, carotenoids, vitamins C and E represent a key group of molecules required for desiccation
Full Text Available Nonsteroidal anti-inflammatory drugs are among the most commonly used prescription and over-the-counter medications, but they often produce significant gastrointestinal ulceration and bleeding, particularly in elderly patients and patients with certain co-morbidities. Novel anti-inflammatory drugs are seldom tested in animal models that mimic the high risk human users, leading to an underestimate of the true toxicity of the drugs. In the present study we examined the effects of two novel NSAIDs and two commonly used NSAIDs in models in which mucosal defence was expected to be impaired. Naproxen, celecoxib, ATB-346 (a hydrogen sulfide- and naproxen-releasing compound and NCX 429 (a nitric oxide- and naproxen-releasing compound were evaluated in healthy, arthritic, obese, and hypertensive rats and in rats of advanced age (19 months and rats co-administered low-dose aspirin and/or omeprazole. In all models except hypertension, greater gastric and/or intestinal damage was observed when naproxen was administered in these models than in healthy rats. Celecoxib-induced damage was significantly increased when co-administered with low-dose aspirin and/or omeprazole. In contrast, ATB-346 and NCX 429, when tested at doses that were as effective as naproxen and celecoxib in reducing inflammation and inhibiting cyclooxygenase activity, did not produce significant gastric or intestinal damage in any of the models. These results demonstrate that animal models of human co-morbidities display the same increased susceptibility to NSAID-induced gastrointestinal damage as observed in humans. Moreover, two novel NSAIDs that release mediators of mucosal defence (hydrogen sulfide and nitric oxide do not induce significant gastrointestinal damage in these models of impaired mucosal defence.
Full Text Available Today, people often talk about biologic agriculture and Integrated Production (IP, even if the real meaning of these terms is altered. In both cases, they deal with production methods characterized by a particular attention to the reduction of the environmental impact of all the farm practices used, especially for defence from adversities, being the element of major concern for environment and consumers’ health.Farm practice evolution, especially those about pest defence, is based on important conceptual change, accurate scientific analysis and organization of technical assistance, rationalization of agri-pharmaceutical product use is one of the main objective of Integrated Production Specifications (IPS. The quantitative reduction is the first objective, obtained by various means such as the use of efficient equipment and the qualitative selection based on the priority use of minor impact means, effectiveness being equal. At post-harvest, the anti-parasitary defence is undergoing deep changes in our country. Once, pesticides very toxic and persistent were used; however, in the last years the availability of active principles (a.p. usable on foodstuffs or in productive environments; for instance, methyl bromide use has been progressively reduced till its banishment because it is recognized to damage the ozone layer. Thus, on the whole we can talk about “integrated pest management” even for the post-harvest sector. However, substantial differences exist between agriculture and post-harvest, thus the integrated pest management in food production environment has to be designed in a different way. The fundamental element of this technique is to identify a tolerance threshold to pest attack but for the defence of food industries and stored foodstuffs is very difficult, if not impossible, to fix a limit to insect presence after which intervening is compulsory. Monitoring of pest attacks and the implementation of prevention practices is
This paper attempts to make a brief assessment of Romania’s parallel processes of integration within NATO and EU-ESDP using as a compass the competitive/complementary dynamic between Europeanism and atlanticism, as well as Romania’s manifest preferences regarding national security and defence. The first part will track the evolution of the accession processes, of the initiatives and reforms put into place on Romania’s behalf in order to comply with euro-Atlantic standards. Next, the NATO-ESDP...
In the paper the author proposes that effectively and efficiently addressing cyber crime requires a shift in paradigm. For businesses and government departments alike the focus should be on prevention, rather than the prosecution of cyber criminals. The Defence in Depth strategy poses a practical solution for achieving Information Assurance in todayâ€™s highly networked environments. In a world where â€œabsolute securityâ€ is an unachievable goal, the concept of Information Assurance poses si...
The Fukushima Daiichi nuclear accident revealed the importance and demand for further reinforcement of defence in- depth. CGN (China General Nuclear Power Group) has made a complete safety assessment on CPR1000 nuclear power plants under construction in China. Dozens of modifications have been implemented based on the assessment findings and lessons learned from Fukushima nuclear accident, taking into account of PSA (Probabilistic Safety Analysis) and comparison analysis of the latest regulations and standards. These modifications help to enhance nuclear safety significantly for nuclear power plants under construction in China, and provide helpful modification guidance for nuclear power plants in operation of the same type. (author)
Drachen, Anders; Yancey, Matthew; Maguire, John; Chu, Derrek; Wang, Iris Yuhui; Mahlmann, Tobias; Schubert, Matthias; Klabjan, Diego
Multiplayer Online Battle Arena (MOBA) games are among the most played digital games in the world. In these games, teams of players fight against each other in arena environments, and the gameplay is focused on tactical combat. Mastering MOBAs requires extensive practice, as is exemplified in the popular MOBA Defence of the Ancients 2 (DotA 2). In this paper, we present three data-driven measures of spatio-temporal behavior in DotA 2: 1) Zone changes; 2) Distribution of team members and: 3) T...
Full Text Available Problem statement: A study of the pattern of Candida spp. infection of the human body and the mode and pattern of reaction of the human body to this infection showed that disease infectivity and self healing by plants followed the same procedures and patterns. Approach: A comparism of these procedures and patterns of natural self- healing of disease infection by the human body and plants/plant parts with the cutaneous Candida spp. killing and elimination procedures and patterns of Vernonia amygdalina leaf extract, showed that cell surface receptors are the sites through which disease infects the body and also the sites at which the body is defended. They are also the sites where activities which result in normal body functioning are carried out. The mode and patterns of Cutaneous Candida infection in a human subject and its containment by the body was examined and photographed. The disease infection and self healing procedures and patterns of plants were also examined in comparism with those of their healthy counterparts and photographed. The findings from the observations on disease infectivity and natural bodys defence patterns and procedures of the plant parts studied and those of the human body in reaction to Candida spp. infection were compared with those of the Candida spp. killing procedures and patterns of aqueous and Arachis hypogeal oil extract of Vernonia amygdalina leaf. Results: The findings of this study also showed that disease-infective organisms gain access to the body of a host through attachment to the cell surface receptors of that host which are placed linearly and are interconnected by channels. The results of the study also indicated that living organisms have a main endogenous substance that mediates both their bodys defence and their normal physiological functioning which is therefore the owner of the cell surface receptor. Other endogenous substances which participate in normal body functioning/bodys defence or in
Over the past years, in books and journals (this journal included), N. Maxwell launched a ferocious attack on B. C. van Fraassen’s view of science called Constructive Empiricism (CE). This attack has been totally ignored. Must we conclude from this silence that no defence is possible and that a fortiori Maxwell has buried CE once and for all? Or is the attack too obviously flawed as not to merit exposure? A careful dissection of Maxwell’s reasoning will make it clear that neither is the case....
The defence right of the criminal proceeding is a basic right of the prosecuted.Whether the defence right is fully used not only concerns the right of the prosecuted,but also influences the justice and public credibility.At the present stag,the defence rate of criminal cases has gradually dropped year by year.The lack of defender results in imbanlance of power between the prosecutor and the defender,leading to the frequent infringement of the prosecuted＇ just right and the wrong cases.In order to improve the judgement of criminal cases,it is necessary to borrow the compulsory defence system to normalize the criminal proceeding for the sake of the protection of the prosecuted＇ basic right,which is of great significance for the development of our criminal law.%刑事诉讼中的辩护权是被追诉人的一项基本权利,辩护权行使的充分与否,不仅关涉被追诉人的切身利益,更影响着司法的公正性和公信力。现阶段我国刑事案件辩护率低且逐年下降,辩护人的缺席导致控辩力量对比失衡,控辩平等对抗近乎空谈,被告人的正当权益屡遭侵害,冤假错案时有发生。为突破这一困境,提高刑事案件审判水平,借鉴引入强制辩护制度尤为重要,通过强制辩护制度,制衡控方公权力行使,规范刑事诉讼活动,切实维护刑事被追诉人的基本权利,对我国刑事诉讼法的发展具有重要意义。
Shetty, N.P.; Jensen, J.D.; Knudsen, A.;
-1,3-glucanase and chitinase transcripts followed by a subsequent reduction in level. Resistance was also associated with high activity of beta-1,3-glucanase, especially in the apoplastic fluid, in accordance with the biotrophic/endophytic lifestyle of the pathogen in the apoplastic spaces, thus...... of callose. Collectively, these data indicate that resistance is dependent on a fast, initial recognition of the pathogen, probably due to beta-1,3-glucan in the fungal cell walls, and this results in the accumulation of beta-1,3-glucanase and structural defence responses, which may directly inhibit...... the pathogen and protect the host against fungal enzymes and toxins....
Lamb, Di; Piper, N
There are many reasons for poor compliance with patient safety incident reporting in the UK. The Defence Medical Services has made a significant investment to address the culture and process by which risk to patient safety is managed within its organisation. This paper describes the decision process and technical considerations in the design of an automated reporting system together with the implementation procedure aimed to maximise compliance. The elimination of inherent weaknesses in feedback mechanisms from the three Armed Forces, which had been uniquely different, ensured the quality of data improved, which enabled resources to be prioritised that would also have a direct impact upon the quality of patient care. PMID:26400974
Požgayová, Milica; Procházka, Petr; Honza, Marcel
Brno : Ústav biologie obratlovců AV ČR, 2008 - (Bryja, J.; Nedvěd, O.; Sedláček, F.; Zukal, J.). s. 165-166 ISBN 978-80-87189-00-9. [Zoologické dny. 14.02.2008-15.02.2008, České Budějovice] R&D Projects: GA AV ČR IAA600930605; GA ČR(CZ) GD524/05/H536 Institutional research plan: CEZ:AV0Z60930519 Keywords : nest defence * brood parasitism * cuckoo Subject RIV: EG - Zoology
Pseudomonas aeruginosa, an extracellular opportunistic pathogen, utilizes two major mechanisms to evade the host defence system. One of these mechanisms is the production of a large number of extracellular products, such as proteases, toxins, and lipases. The two proteases, alkaline protease and...... elastase, inhibit the function of the cells of the immune system (phagocytes, NK cells, T cells), inactivate several cytokines (IL-1, IL-2, IFN-r, TNF), cleave immunoglobulins and inactivate complement. Inhibition of the local immune response by bacterial proteases provides an environment for the...
Carlos Echeverría Jesús
Cooperation between Spain and the Maghreb states in the area of defence represents a sphere that includes long-term historical links (for example, with Morocco) with other relations that have been developing in recent years, and at varying rates of intensity. Theprogressive normalising of the situation in Algeria since the 1990s, the raising of the UN embargo against Libya and the rise of what are called “new dangers” (all kinds of illegal trading and a style of terrorism that is increasingly...
Pickett, John A; Birkett, Michael A; Bruce, Toby J A; Chamberlain, Keith; Gordon-Weeks, Ruth; Matthes, Michaela C; Napier, Johnathan A; Smart, Lesley E; Woodcock, Christine M
The challenges and opportunities for protecting agricultural production of food and other materials will be met through exploiting the induction of defence pathways in plants to control pests, diseases and weeds. These approaches will involve processes that can be activated by application of natural products, patented in terms of this use, to "switch on" defence pathways. Already, a number of secondary metabolite defence compounds are known for which the pathways are conveniently clustered genomically, e.g. the benzoxazinoids (hydroxamic acids) and the avenacins. For the former, it is shown that the small molecular weight lipophilic activator cis-jasmone can induce production of these compounds and certain genes within the pathway. Numerous groups around the world work on inducible defence systems. The science is rapidly expanding and involves studying the interacting components of defence pathways and the switching mechanisms activated by small molecular weight lipophilic compounds. Examples are described of how plant breeding can exploit these systems and how heterologous gene expression will eventually give rise to a new range of GM crops for food and energy, without the need for external application of synthetic pesticides. PMID:18023830
Gagan Bihari Nityananda Chainy
Full Text Available Antioxidant defence system, a highly conserved biochemical mechanism, protects organisms from harmful effects of reactive oxygen species (ROS, a by-product of metabolism. Both invertebrates and vertebrates are unable to modify environmental physical factors such as photoperiod, temperature, salinity, humidity, oxygen content, and food availability as per their requirement. Therefore, they have evolved mechanisms to modulate their metabolic pathways to cope their physiology with changing environmental challenges for survival. Antioxidant defences are one of such biochemical mechanisms. At low concentration, ROS regulates several physiological processes, whereas at higher concentration they are toxic to organisms because they impair cellular functions by oxidizing biomolecules. Seasonal changes in antioxidant defences make species able to maintain their correct ROS titre to take various physiological functions such as hibernation, aestivation, migration, and reproduction against changing environmental physical parameters. In this paper, we have compiled information available in the literature on seasonal variation in antioxidant defence system in various species of invertebrates and vertebrates. The primary objective was to understand the relationship between varied biological phenomena seen in different animal species and conserved antioxidant defence system with respect to seasons.
Travassos, B; Bourbousson, J; Esteves, P T; Marcelino, R; Pacheco, M; Davids, K
This study evaluated tendencies towards flexibility/stability of coordinated behaviours in international futsal teams, considered as complex collective systems, according to changes in opposition defensive formations. Six games of two international futsal teams (Spain and Portugal) were selected for Social Network Analysis to capture the coordination tendencies that emerge in the tactical behaviours of players when performing against different defensive formations. Ball trajectories in each offensive pattern of play were notated in an adjacency matrix where each entry accounted for the linkages between 12 spatial field areas. Each offensive play was coded according to the defensive formation of an opposing team (i.e. conservative or risky formation). Results revealed similar network properties between teams when competing against more risky defensive formations, while notable differences were observed against conservative defences. Effect of defensive formation of opponents on macro network properties was observed in both the Portuguese and Spanish teams. At a meso-level, only the Spanish national team exhibited notable changes, suggesting a greater level of adaptability to unfolding performance events. The observed flexibility in tactical behaviours of the Spanish team appeared to express their greater expertise levels. PMID:26918489
Grootelaar, Hilke; Waterbolk, Tjalling; Winkels, Jakoline
This paper presents the results of eight case studies of post-defence hearings in a Dutch court, in which the judge was questioned about his role conception, judicial behaviour at the hearing was observed and parties were interviewed about their perception of procedural justice after the hearing. A large part of the findings are in line with former research on procedural justice. Nevertheless, self-generated answers by the respondents revealed interesting miscellaneous findings. The main aim ...
Parental bonding instrument (PBI),Proactive coping scale (PCS)and Altruistic behavior questionnaire were adopted to investigate 272 college student volunteers in an attempt to find out about the influence of parenting styles,the proactive coping on their altruistic behaviors in Guangdong.The results showed that:Altruistic behaviors were positively correlated with the care factor and proactive coping factor in the parenting styles;Mother care and proactive coping,as the suppression variables,can enhance the predictive validity of father control upon the altruistic behavior.The mediator effect of the Father care can fully effect upon the altruistic behavior via the proactive coping approach(the mediating effect value reaches as high as 79.42%),while the mediator effect of mother care is partially effected upon the altruistic behavior via the proactive coping with a mediating effect value of about 31.38%),indicating that the parenting style indirectly influences college student volunteer’altruistic behaviors via the mediation of proactive coping.%为了了解大学生志愿者父母教养方式、前瞻性应对方式对其利他行为的影响，采用父母教养方式量表、前瞻性应对方式与利他行为自陈问卷对广东省272名大学生志愿者进行调查.结果显示：父母教养方式的关爱维度、前瞻性应对方式和利他行为之间存在显著的正相关；母亲关爱和前瞻性应对方式作为抑制变量会增强父亲控制对利他行为的预测效应；父亲关爱通过前瞻性应对方式完全中介作用于利他行为，中介效应为79.42%，母亲关爱通过前瞻性应对方式部分中介作用于利他行为，中介效应为31.38%.由此可见，父母教养方式会通过前瞻性应对方式间接影响大学生志愿者的利他行为.
Nutrition, neurotoxicants and aggressive behaviour Antisocial behaviour, such as violence, is explained not only by the social environment, as was long believed. Also nutrients and neurotoxicants might play a role. Whether this is the case was studied in this thesis. In two empirical studies possibl
Andolina, Rosanna; Locuratolo, Elvira
An approach of behavioural modelling based on the specialization concept is proposed within ASSO, a formal database design methodology which combines features from database design with formal methods. This approach preserves the semantics of the current behavioural modelling while producing benefits on the phases of the methodology.
Yano, Shuichi; Shirotsuka, Kanako
An antipredator defence in the citrus red mite Panonychus citri, which does not produce protective webs, was examined experimentally. P. citri adult females lie down on citrus leaf surfaces with their dorsal setae (hair) directed in all upper directions. They seldom move in response to physical stimuli. Compared to normal lying females, both manipulated non-lying females and hair-removed females suffered higher predation by predatory mites. A predator approaching the body surface of a lying female inevitably created elasticity with a confronting seta, which eventually repelled the predator away from the female. These observations indicated that lying down with protective setae functions as an antipredator defence in P. citri females. This inflexible defence could also explain why the mite rarely runs away, even when it is consumed together with host plant leaves (via coincidental intraguild predation) by gigantic swallowtail caterpillars, against which protective setae are totally ineffective. PMID:24312748
Full Text Available The seed stage is often critical in determining the regeneration success of plants. Seeds must survive an array of seed predators and pathogens and germinate under conditions favourable for seedling establishment. To maximise recruitment success plants protect seeds using a diverse set of chemical and physical defences. However, the relationship between these defence classes, and their association with other life history traits, is not well understood. Data on seed coat thickness and fracture resistance, and the abundance and diversity of potential defensive compounds were collected for 10 tree species of Macaranga from Borneo. The data were used to test whether there is a trade-off in physical versus chemical defence investment, and to determine how investment varies with seed mass, and light requirement for regeneration. Across species there was no correlation between seed coat thickness and abundance of potential defensive compounds, indicating the absence of a direct trade-off between defence classes. While chemical defences were not correlated to other traits, physical defences were positively correlated with light requirement for regeneration. For a subset of five Macaranga species we evaluated the relative investment in chemical and physical defence to seed persistence in the soil, measured as the time to half initial seed viability (seed half-life. Half-life was negatively related to the ratio of potential defensive compound abundance to seed coat thickness, suggesting that species with long persistence invested in physical defence more than stored chemical defences. These results indicate that investment in seed defences are associated with species' light requirements for regeneration, rather than scaling positively with seed mass. Furthermore, chemical defences, although highly variable among species, do not appear to be critical to long term persistence of Macaranga seeds, and may be important in defending seeds from natural enemies
Najda, Stephen P.; Perlin, Piotr; Suski, Tadek; Marona, Lujca; Boćkowski, Mike; Leszczyński, Mike; Wisniewski, Przemek; Czernecki, Robert; Kucharski, Robert; Targowski, Grzegorz; Watson, Scott; Kelly, Antony E.
AlGaInN laser diodes is an emerging technology for defence and security applications such as underwater communications and sensing, atomic clocks and quantum information. The AlGaInN material system allows for laser diodes to be fabricated over a very wide range of wavelengths from u.v., ~380nm, to the visible ~530nm, by tuning the indium content of the laser GaInN quantum well. Thus AlGaInN laser diode technology is a key enabler for the development of new disruptive system level applications in displays, telecom, defence and other industries. Ridge waveguide laser diodes are fabricated to achieve single mode operation with optical powers up to 100mW with the 400-440nm wavelength range with high reliability. Visible free-space and underwater communication at frequencies up to 2.5GHz is reported using a directly modulated 422nm GaN laser diode. Low defectivity and highly uniform GaN substrates allow arrays and bars to be fabricated. High power operation operation of AlGaInN laser bars with up to 20 emitters have been demonstrated at optical powers up to 4W in a CS package with common contact configuration. An alternative package configuration for AlGaInN laser arrays allows for each individual laser to be individually addressable allowing complex free-space or optical fibre system integration with a very small form-factor.
Reinisalo, Mika; Kårlund, Anna; Koskela, Ali; Kaarniranta, Kai; Karjalainen, Reijo O
Numerous studies have highlighted the key roles of oxidative stress and inflammation in aging-related diseases such as obesity, type 2 diabetes, age-related macular degeneration (AMD), and Alzheimer's disease (AD). In aging cells, the natural antioxidant capacity decreases and the overall efficiency of reparative systems against cell damage becomes impaired. There is convincing data that stilbene compounds, a diverse group of natural defence phenolics, abundant in grapes, berries, and conifer bark waste, may confer a protective effect against aging-related diseases. This review highlights recent data helping to clarify the molecular mechanisms involved in the stilbene-mediated protection against oxidative stress. The impact of stilbenes on the nuclear factor-erythroid-2-related factor-2 (Nrf2) mediated cellular defence against oxidative stress as well as the potential roles of SQSTM1/p62 protein in Nrf2/Keap1 signaling and autophagy will be summarized. The therapeutic potential of stilbene compounds against the most common aging-related diseases is discussed. PMID:26180583
Ibiza, Sales; García-Cassani, Bethania; Ribeiro, Hélder; Carvalho, Tânia; Almeida, Luís; Marques, Rute; Misic, Ana M; Bartow-McKenney, Casey; Larson, Denise M; Pavan, William J; Eberl, Gérard; Grice, Elizabeth A; Veiga-Fernandes, Henrique
Group 3 innate lymphoid cells (ILC3) are major regulators of inflammation and infection at mucosal barriers. ILC3 development is thought to be programmed, but how ILC3 perceive, integrate and respond to local environmental signals remains unclear. Here we show that ILC3 in mice sense their environment and control gut defence as part of a glial–ILC3–epithelial cell unit orchestrated by neurotrophic factors. We found that enteric ILC3 express the neuroregulatory receptor RET. ILC3-autonomous Ret ablation led to decreased innate interleukin-22 (IL-22), impaired epithelial reactivity, dysbiosis and increased susceptibility to bowel inflammation and infection. Neurotrophic factors directly controlled innate Il22 downstream of the p38 MAPK/ERK-AKT cascade and STAT3 activation. Notably, ILC3 were adjacent to neurotrophic-factor-expressing glial cells that exhibited stellate-shaped projections into ILC3 aggregates. Glial cells sensed microenvironmental cues in a MYD88-dependent manner to control neurotrophic factors and innate IL-22. Accordingly, glial-intrinsic Myd88 deletion led to impaired production of ILC3-derived IL-22 and a pronounced propensity towards gut inflammation and infection. Our work sheds light on a novel multi-tissue defence unit, revealing that glial cells are central hubs of neuron and innate immune regulation by neurotrophic factor signals. PMID:27409807
Gilding, Edward K; Jackson, Mark A; Poth, Aaron G; Henriques, Sónia Troeira; Prentis, Peter J; Mahatmanto, Tunjung; Craik, David J
Plants have evolved many strategies to protect themselves from attack, including peptide toxins that are ribosomally synthesized and thus adaptable directly by genetic polymorphisms. Certain toxins in Clitoria ternatea (butterfly pea) are cyclic cystine-knot peptides of c. 30 residues, called cyclotides, which have co-opted the plant's albumin-1 gene family for their production. How butterfly pea albumin-1 genes were commandeered and how these cyclotides are utilized in defence remain unclear. The role of cyclotides in host plant ecology and biotechnological applications requires exploration. We characterized the sequence diversity and expression dynamics of precursor and processing proteins implicated in butterfly pea cyclotide biosynthesis by expression profiling through RNA-sequencing (RNA-seq). Peptide-enriched extracts from various organs were tested for activity against insect-like membranes and the model nematode Caenorhabditis elegans. We found that the evolution and deployment of cyclotides involved their diversification to exhibit different chemical properties and expression between organs facing different defensive challenges. Cyclotide-enriched fractions from soil-contacting organs were effective at killing nematodes, whereas similar enriched fractions from aerial organs contained cyclotides that exhibited stronger interactions with insect-like membrane lipids. Cyclotides are employed as versatile and combinatorial mediators of defence in C. ternatea and have specialized to affect different classes of attacking organisms. PMID:26668107
Rebecca K. Helm
Full Text Available The present study investigated the impact of different legal standards on mock juror decisions concerning whether a defendant was guilty or not guilty by reason of insanity. Undergraduate students (N = 477 read a simulated case summary involving a murder case and were asked to make an insanity determination. The cases differed in terms of the condition of the defendant (rationality deficit or control deficit and the legal standard given to the jurors to make the determination (Model Penal Code, McNaughten or McNaughten plus a separate control determination. The effects of these variables on the insanity determination were investigated. Jurors also completed questionnaires measuring individualism and hierarchy attitudes and perceptions of facts in the case. Results indicate that under current insanity standards jurors do not distinguish between defendants with rationality deficits and defendants with control deficits regardless of whether the legal standard requires them to do so. Even defendants who lacked control were found guilty at equal rates under a legal standard excusing rationality deficits only and a legal standard excluding control and rationality deficits. This was improved by adding a control test as a partial defence, to be determined after a rationality determination. Implications for the insanity defence in the Criminal Justice System are discussed.
Rosin, Zuzanna M; Kobak, Jarosław; Lesicki, Andrzej; Tryjanowski, Piotr
One of the most spectacular evolutionary forces is predation, evidenced to stimulate polymorphism in many prey species. Shell colour polymorphism of the land snail Cepaea nemoralis is a well-known model in evolutionary research. Nevertheless, the knowledge on the ecological causes driving its evolution remains incomplete and proximal factors shaping predatory pressure on C. nemoralis morphs are unknown. We evaluated shell crushing resistance and thickness, constituting crucial snail anti-predator defences in two shell areas (the apex and labium) of eight C. nemoralis morphotypes differing in shell colour and banding pattern. A GLM showed a significant effect of shell colour, banding pattern and shell thickness on shell strength. Pink shells were stronger than yellow ones, and banded forms had stronger shells than unbanded snails. The labium (usually attacked by mice) was generally thicker and more resistant than the apex (usually crushed by birds). Thicker shells were more resistant to crushing, and the rate of shell strength increase per unit of shell thickness was greater in pink and banded individuals compared to yellow and unbanded ones. Yellow and unbanded morphs have been found to be preferred by mice in the previous studies, which suggests that shell strength may be an important trait used in prey selection by these shell-crushing predators. The differences in potential anti-predator defences among snail morphs, found in the present study, justify future research on direct effect of C. nemoralis morphs shell strength on predator selectivity. PMID:23921905
Rosin, Zuzanna M.; Kobak, Jarosław; Lesicki, Andrzej; Tryjanowski, Piotr
One of the most spectacular evolutionary forces is predation, evidenced to stimulate polymorphism in many prey species. Shell colour polymorphism of the land snail Cepaea nemoralis is a well-known model in evolutionary research. Nevertheless, the knowledge on the ecological causes driving its evolution remains incomplete and proximal factors shaping predatory pressure on C. nemoralis morphs are unknown. We evaluated shell crushing resistance and thickness, constituting crucial snail anti-predator defences in two shell areas (the apex and labium) of eight C. nemoralis morphotypes differing in shell colour and banding pattern. A GLM showed a significant effect of shell colour, banding pattern and shell thickness on shell strength. Pink shells were stronger than yellow ones, and banded forms had stronger shells than unbanded snails. The labium (usually attacked by mice) was generally thicker and more resistant than the apex (usually crushed by birds). Thicker shells were more resistant to crushing, and the rate of shell strength increase per unit of shell thickness was greater in pink and banded individuals compared to yellow and unbanded ones. Yellow and unbanded morphs have been found to be preferred by mice in the previous studies, which suggests that shell strength may be an important trait used in prey selection by these shell-crushing predators. The differences in potential anti-predator defences among snail morphs, found in the present study, justify future research on direct effect of C. nemoralis morphs shell strength on predator selectivity.
Silveyra, Patricia; Floros, Joanna
An appropriate immune and inflammatory response is key to defend against harmful agents present in the environment, such as pathogens, allergens and inhaled pollutants, including ozone and particulate matter. Air pollution is a serious public health concern worldwide, and cumulative evidence has revealed that air pollutants contribute to epigenetic variation in several genes, and this in turn can contribute to disease susceptibility. Several groups of experts have recently reviewed findings on epigenetics and air pollution [1-6]. Surfactant proteins play a central role in pulmonary host defence by mediating pathogen clearance, modulating allergic responses and facilitating the resolution of lung inflammation. Recent evidence indicates that surfactant proteins are subject to epigenetic regulation under hypoxia and other conditions. Oxidative stress caused by ozone, and exposure to particulate matter have been shown to affect the expression of surfactant protein A (SP-A), an important lung host defence molecule, as well as alter its functions. In this review, we discuss recent findings in the fields of epigenetics and air pollution effects on innate immunity, with the focus on SP-A, and the human SP-A variants in particular. Their function may be differentially affected by pollutants and specifically by ozone-induced oxidative stress, and this in turn may differentially affect susceptibility to lung disease. PMID:22553125
Rix, K J
A man was charged with driving over the prescribed alcohol limit. Both specimens of breath contained less than 50 micrograms of alcohol per 100 ml and he refused to submit to a blood test. His defence was that he had a phobia of blood and that he should have been allowed to claim to replace the breath specimens with a specimen of urine. Evidence that he had a phobia was accepted by the prosecution. A woman was arrested on suspicion of driving whilst unfit through drink or drugs. She was charged with refusing to provide a specimen of blood. It was her defence that she had a phobia of needles. Evidence that she had a phobia was not accepted by the prosecution. In both cases the court was asked to decide whether or not the forensic medical examiner had been seriously wrong in deciding that there was no medical reason for refusing a specimen of blood. The man was acquitted and the woman was found guilty. These cases are used to describe the law relating to blood or needle phobias and to suggest how such cases should be approached by the police and forensic medical examiners. PMID:15335604
Sánchez-Elordi, Elena; Baluška, František; Echevarría, Clara; Vicente, Carlos; Legaz, M Estrella
Microtubules (MTs) are involved in the germination of Sporisorium scitamineum teliospores. Resistant varieties of sugar cane plants produce defence glycoproteins that prevent the infection of the plants by the filamentous fungi Sporisorium scitamineum. Here, we show that a fraction of these glycoproteins prevents the correct arrangement of MTs and causes nuclear fragmentation defects. As a result, nuclei cannot correctly migrate through the growing hyphae, causing germinative failure. Arginase activity contained in defence glycoproteins is already described for preventing fungal germination. Now, its enzymatically active form is presented as a link between the defensive capacity of glycoproteins and the MT disorganization in fungal cells. Active arginase is produced in healthy and resistant plants; conversely, it is not detected in the juice from susceptible varieties, which explains why MT depolarization, nuclear disorganization as well as germination of teliospores are not significantly affected by glycoproteins from non-resistant plants. Our results also suggest that susceptible plants try to increase their levels of arginase after detecting the presence of the pathogen. However, this signal comes "too late" and such defensive mechanism fails. PMID:27372179
P G Kavitha; George Thomas
Soft rot is a serious disease in ginger (Zingiber officinale Roscoe), imposing a considerable economic loss annually in all ginger-producing countries. In this study, mRNA differential display was employed to identify genes whose expression was altered in a soft rot-resistant accession of Zingiber zerumbet (L.) Smith, a wild relative of ginger, in response to Pythium aphanidermatum (Edson) Fitzp., which is the principal causative agent of soft-rot disease in ginger. Analysis using 68 primer combinations identified 70 differentially expressed transcript-derived fragments (TDFs), of which 34 TDFs were selected for further analysis following reverse northern screening. Cloning and sequence characterization of the 34 TDFs yielded a total of 54 distinct clones. Functional categorization of these clones revealed seven categories, of which the defence/stress/signalling group was the largest, with clones homologous to genes known to be actively involved in various pathogenesis-related functions in other plant species. The significance of these genes in relation to the resistance response in Z. zerumbet is discussed. This study has provided a pool of candidate genes for detailed molecular dissection of the defence mechanisms in Z. zerumbet and for accessing wild genetic resources for the transgenic improvement of ginger.
Foxall, G.R.; Oliveira-Castro, J.M.; James, V.K.; Schrezenmaier, T.C.
This is the FIRST of TWO linked articles on consumer behavioural analysis. Cognitive theories have dominated the field of consumer behaviour for the last few decades, however, an observed lack of consistency between attitudes and behaviour has suggested the need to investigate more thoroughly situational and behavioural variables. Consumer behaviour analysis can be viewed as an alternative theoretical approach that emphasizes situational variables and measures of behaviour. Within consumer be...
Brañas-Garza, Pablo; Rascón-Ramírez, Ericka
Previous research shows that women are more altruist than men in dictator game experiments. Yet, little is known whether women are expected to be more altruist than men. Here we elicit third-parties' beliefs about dictators' donations conditional on knowing the gender of the dictator. Our data provide evidence of three main findings: (i) women are expected to be more altruist than men; (ii) both men and women have correct beliefs about the level of altruism among men; and (iii) both men and women overestimate the level of altruism among women. In doing so, our results uncover a perception gap according to which, although women are more altruist than men, they are expected to be even more altruist than they actually are.
Full Text Available The development of structural defences, such as the fortification of shells or exoskeletons, is a widespread strategy to reduce predator attack efficiency. In unpredictable environments these defences may be more pronounced in the presence of a predator. The cladoceran Daphnia magna (Crustacea: Branchiopoda: Cladocera has been shown to develop a bulky morphotype as an effective inducible morphological defence against the predatory tadpole shrimp Triops cancriformis (Crustacea: Branchiopoda: Notostraca. Mediated by kairomones, the daphnids express an increased body length, width and an elongated tail spine. Here we examined whether these large scale morphological defences are accompanied by additional ultrastructural defences, i.e. a fortification of the exoskeleton. We employed atomic force microscopy (AFM based nanoindentation experiments to assess the cuticle hardness along with tapping mode AFM imaging to visualise the surface morphology for predator exposed and non-predator exposed daphnids. We used semi-thin sections of the carapace to measure the cuticle thickness, and finally, we used fluorescence microscopy to analyse the diameter of the pillars connecting the two carapace layers. We found that D. magna indeed expresses ultrastructural defences against Triops predation. The cuticle in predator exposed individuals is approximately five times harder and two times thicker than in control daphnids. Moreover, the pillar diameter is significantly increased in predator exposed daphnids. These predator-cue induced changes in the carapace architecture should provide effective protection against being crushed by the predator's mouthparts and may add to the protective effect of bulkiness. This study highlights the potential of interdisciplinary studies to uncover new and relevant aspects even in extensively studied fields of research.
白文辉; 张瑞星; 孙小雨
[目的]预防和减少感染科患儿跌倒和坠床的发生。[方法]了解不同年级本科护理专业在校学生(以下简称护生)的移情与利他观念现状，分析二者相关性。[方法]采用大学生移情量表和大学生利他行为量表，对299名1年级~3年级本科护生进行问卷调查。[结果]①不同年级本科在校护生移情得分无统计学意义(P>0.05)，不同性别护生的情感移情得分有统计学意义(P0.05)；③移情总得分及各维度(认知移情、情感移情、行为移情)得分分别与利他行为总得分呈正相关(P0.05),and there was statis-tical significance in the emotional empathy scores among the different gen-ders of nursing students(P0.05);The total scores of empathy and each dimension score (cognitive empathy,emotional empathy,behavior empathy )were respec-tively positively correlated with the total scores of the altruistic behaviors (P<0.001).Conclusion:To carry out the empathy education in nursing education as soon as possible and select empathy training ways pertinently is the effective way to promote the altruistic behavior of nursing students.
Percox, David A.
This thesis fills a significant gap in current secondary literature on post-war British defence and internal security policy. Hitherto, post-war British defence policy in Kenya has only been considered in passing, in relation to the larger question of Middle East strategy. Very little attention has been paid to Kenya's particular importance in the post-1956 ‘east of Suez’ role. Current works on British internal security policy in Kenya concentrate either on post-war policing in general or, mo...
Changes in the conditions governing international safety call for a re-orientation in civil defence policy. The 23 papers presented to the meetings address aspects such as external hazards, including illicit trafficking with nuclear materials, novel risks emanating from the population growth rates, the international refugee problem, environmental issues, and new approaches in civil defence policy also encompassing emergency preparedness under the responsibility of the Laender. Futher topics discussed are proposals for improvement of first-aid medical care, or new approaches in concepts for risk identification and management as well as preventive action. (DG)
Mondet, Fanny; Alaux, Cédric; Severac, Dany; Rohmer, Marine; Mercer, Alison R; Le Conte, Yves
In honey bees, Varroa sensitive hygiene (VSH) behaviour, which involves the detection and removal of brood parasitised by the mite Varroa destructor, can actively participate in the survival of colonies facing Varroa outbreaks. This study investigated the mechanisms of VSH behaviour, by comparing the antennal transcriptomes of bees that do and do not perform VSH behaviour. Results indicate that antennae likely play a key role in the expression of VSH behaviour. Comparisons with the antennal transcriptome of nurse and forager bees suggest that VSH profile is more similar to that of nurse bees than foragers. Enhanced detection of certain odorants in VSH bees may be predicted from transcriptional patterns, as well as a higher metabolism and antennal motor activity. Interestingly, Deformed wing virus/Varroa destructor virus infections were detected in the antennae, with higher level in non-VSH bees; a putative negative impact of viral infection on bees' ability to display VSH behaviour is proposed. These results bring new perspectives to the understanding of VSH behaviour and the evolution of collective defence by focusing attention on the importance of the peripheral nervous system. In addition, such data might be useful for promoting marker-assisted selection of honey bees that can survive Varroa infestations. PMID:26000641
Suicidal behaviour is a serious public health issue. Suicidal behaviour includes completed suicide, suicide attempts, suicidal intent and/or plans and suicide ideation. Two prominent mechanisms, behavioural deficits, in particular poor problem-solving skills, and a certain cognitive style with overgeneralization, distortion and lack of positive expectations, have been identified in suicidal patients so far. Besides general therapy strategies, including the diagnostic process and a collaborative, confident relationship and strengthening of protective factors, specific behavioural strategies should aim at the modification of the behavioural repertoire and of cognitive strategies. The modification of the behavioural repertoire includes the direct modification of the behaviour, acquiring techniques for stress reduction and learning problem-solving strategies. Applied cognitive techniques comprise such as thought-stopping, examining options and alternatives, fantasizing consequences, externalizing inner voices, and reattribution. Psychotherapy with suicidal patients has a specific feature: It requires high activity of the therapist in terms of motivation and guidance of the patient. Regular assessment of the suicide risk at every session is a must. Nevertheless, the therapist should always be aware that it is impossible to prevent all suicidal acts. PMID:22926057
Pate, Russell R; Mitchell, Jonathan A; Byun, Wonwoo; Dowda, Marsha
The purpose of this review is to describe the amount of time children spend in sedentary behaviour and to determine if there are specific factors that associate with sedentary behaviour in children. The following search terms were used to identify relevant articles: sedentary behaviour, inactivity, television, computer, video games, small screen, sitting, prevalence, patterns, correlates, factors and determinants. The databases used to conduct the search included PubMed, PsycINFO, ERIC (Education Resources Information Center) and Academic Search Premier. The studies reviewed were limited to those that sampled children (2-18 years), were written in English and used a measure of sedentary behaviour as the dependent variable. Several studies reported the time spent watching television or the proportion of children at or above a threshold for television viewing (eg, ≥3 h/day). Among the accelerometer studies included, the National Health and Nutrition Examination Survey is the largest and reported ∼6.1, 7.5 and 8.0 h/day mean sedentary time in children 6-11, 12-15 and 16-19 years old, respectively. Taken together, the existing literature across the world indicates a slightly higher level of sedentary behaviour in older children. Higher levels of sedentary behaviour were also reported in non-white children, children from lower socioeconomic status background and children from households with more access to televisions/computers. Lower levels of sedentary behaviour were reported in children whose parents have rules/limitations on screen time. PMID:21836174
Skinner, B F
In this paper it is argued that cognitive scientists, claiming the support of brain science and computer simulation, have revived a traditional view that behaviour is initiated by an internal, autonomous mind. In doing so, they have misused the metaphor of storage and retrieval, given neurology a misleading assignment, frequently replaced controlled experimental conditions with mere descriptions of conditions and the assessment of behaviour with statements of expectations and intentions, given feelings and states of mind the status of causes of behaviour rather than the products of the causes, and failed to define many key terms in dimensions acceptable to science. PMID:4041702
Turecki, Gustavo; Brent, David A
Suicide is a complex public health problem of global importance. Suicidal behaviour differs between sexes, age groups, geographic regions, and sociopolitical settings, and variably associates with different risk factors, suggesting aetiological heterogeneity. Although there is no effective algorithm to predict suicide in clinical practice, improved recognition and understanding of clinical, psychological, sociological, and biological factors might help the detection of high-risk individuals and assist in treatment selection. Psychotherapeutic, pharmacological, or neuromodulatory treatments of mental disorders can often prevent suicidal behaviour; additionally, regular follow-up of people who attempt suicide by mental health services is key to prevent future suicidal behaviour. PMID:26385066
In the beginning of the twentieth century, when Jacques Loeb's and John Watson's mechanistic view of life started to dominate animal physiology and behavioural biology, several scientists with different academic backgrounds got engaged in studying the wayfinding behaviour of ants. Largely unaffected by the scientific spirit of the time, they worked independently of each other in different countries: in Algeria, Tunisia, Spain, Switzerland and the United States of America. In the current literature on spatial cognition these early ant researchers-Victor Cornetz, Felix Santschi, Charles Turner and Rudolf Brun-are barely mentioned. Moreover, it is virtually unknown that the great neuroanatomist Santiago Ramón y Cajal had also worked on spatial orientation in ants. This general neglect is certainly due to the fact that nearly all these ant researchers were scientific loners, who did their idiosyncratic investigations outside the realm of comparative physiology, neurobiology and the behavioural sciences of the time, and published their results in French, German, and Spanish at rather inaccessible places. Even though one might argue that much of their work resulted in mainly anecdotal evidence, the conceptual approaches of these early ant researchers preempt much of the present-day discussions on spatial representation in animals. PMID:26898725
Full Text Available For centuries, the maritime defence of South Africa was a colonial responsibility. First performed by the Dutch, the British took over the task after they wrestled the Cape of Good Hope from the Dutch. The Cape was of supreme strategic value to Britain as the link with India and a great part of her empire. Therefore for more than a century and a half (from 1806 to the abrogation of the Simon's Town Agreement the Royal Navy had a constant presence in South African territorial waters. Furthermore when the first flickers of an indigenous maritime defence organisation appeared in South Africa it was British in character. The South African Division of the part-time Royal Naval Voluntary Reserve (RNVR came into being long before the country had a navy. The origin of the South African Navy dates back to 1922, when, the South African Naval Service was created with the arrival of three small ships from Britain. Unfortunately, the budget cuts during the Depression meant that these ships and their crews were paid off (in 1933-4 and only a skeleton staff remained. This was still the position at the outbreak of the Second World War in 1939. The Union of South Africa's declaration of war against Germany on 6 September 1939, meant that the country's utterly neglected Navy had to suddenly prepare for war. Ships had to be found, and as purpose-build warships were out of the question, ships from the country's fishing fleet and trade had to suffice. A small ocean-going navy was created for the defence of the Union's ports and coastline. Following an urgent request from the British Admiralty in November 1940, South Africa sent four anti-submarine vessels to join the Royal Navy in the Mediterranean. As the war progressed, more ships of the South African Naval Forces arrived in the Mediterranean. They were used for a variety of tasks, ranging from minesweeping to salvage work. South African ships and crews earned themselves quite a reputation, participating in most
The notion of elementarity is considered as a concept on which a motivation of quantum behaviour may be founded. The definition of velocity of an elementary body, in particular, is examined in comparison with the classical situation. (author)
Schlenker, Anna; Šárek, M.
Prague, 2013, nestr. [EFMI 2013 Special Topic Conference. Prague (CZ), 17.04.2013-19.04.2013] Institutional support: RVO:67985807 Keywords : biometrics * behavioural biometrics * keystroke dynamics * mouse dynamics Subject RIV: IN - Informatics, Computer Science
Economic arguments, such as saving money, are often used to promote pro-environmental actions -- for example, reducing energy use. However, research shows that people's environmental motives are sometimes better drivers of behavioural change.
Gill, P.S.; Mäkelä, M.; Vermeulen, K.M.;
The aim of this overview was to identify interventions that change doctor prescribing behaviour and to derive conclusions for practice and further research. Relevant studies (indicating prescribing as a behaviour change) were located from a database of studies maintained by the Cochrane Collabora......The aim of this overview was to identify interventions that change doctor prescribing behaviour and to derive conclusions for practice and further research. Relevant studies (indicating prescribing as a behaviour change) were located from a database of studies maintained by the Cochrane...... Collaboration on Effective Professional Practice. This register is kept up to date by searching the following databases for reports of relevant research: DHSS-DATA; EMBASE; MEDLINE; SIGLE; Resource Database in Continuing Medical Education (1975-1994), along with bibliographies of related topics, hand searching...
A number of experiments and observations on the behaviour, host associations, attractants for adults and pupation of the South American fruit fly Anastrepha fraterculus (Wiedemann), conducted under field or semi-natural conditions are presented here. (author)
Sanad,, R; Cassidy, T.
Drapeability is one of the most important visual properties affecting garment appearance. Even though there are many studies concerned with fabric drape, understanding about the drape behaviour of garments is very limited. This study analyzes the key properties affecting the drape behaviour of garments to provide prediction equations. Results are statistically analyzed. From multiple regression analysis, drape rank scores obtained from subjective analyses are predicted using weight, bending m...
Hamlett, C. A. E.; Shirtcliffe, N. J.; McHale, G.; Ahn, S.; Doerr, S. H.; Bryant, R.; Newton, M. I.
Extreme soil water repellency can occur in nature via condensation of volatile organic compounds released during wildfires and can lead to increased erosion rate. Such extreme water repellent soil can be classified as superhydrophobic and shares similar chemical and topographical features to specifically designed superhydrophobic surfaces. Previous studies using high speed videography to investigate single droplet impact behaviour on artificial superhydrophobic have revealed three distinct modes of splash behaviour (rebound, pinned and fragmentation) which are dependent on the impact velocity of the droplet. In our studies, using high-speed videography, we show that such splash behaviour can be replicated on fixed 'model' water repellent soils (hydrophobic glass beads/particles). We show that the type of splash behaviour is dependent on both the size and chemical nature of the fixed particles. The particle shape also influences the splash behaviour as shown by drop impact experiments on fixed sand samples. We have also studied soil samples, as collected from the field, which shows that the type of droplet splash behaviour can lead to enhanced soil particle transport.
Kammerhofer, N.; Radakovic, Z.; Regis, J.M.A.; Dobrev, Petre; Vaňková, Radomíra; Grundler, F.M.W.; Siddique, S.; Hofmann, J.; Wieczorek, K.
Roč. 207, č. 3 (2015), s. 778-789. ISSN 0028-646X R&D Projects: GA MŠk LD14120 Institutional support: RVO:61389030 Keywords : defence responses * early infection * ethylene Subject RIV: ED - Physiology Impact factor: 7.672, year: 2014
A number of authors consider that the early period of US security and education (1950-1970) was in some way a "golden age" where there was a prevailing societal orientation towards civil defence. This is supported, to some extent, through "Duck and Cover" type activities in schools and in community preparedness efforts. This…
Taylor, D.; Huiskamp, W.; Kvernsveen, K.; Wood, C.
This paper presents the preliminary results of the NATO Modelling and Simulation Group 039 / Task Group 027 “Modelling and Simulation Support of Extended Air Defence Command and Control Interoperability”. This activity is the second of three phases of NMSG Technical Activity Programs (TAP) that bega
Gruden, K.; Kuipers, A.G.J.; Guncar, G.; Slapar, N.; Strukelj, B.; Jongsma, M.A.
Potato synthesises high levels of proteinase inhibitors in response to insect attack. This can adversely affect protein digestion in the insects, leading to reduced growth, delayed development and lowered fecundity. Colorado potato beetle overcomes this defence mechanism by changing the composition
Su, Qi; Mescher, Mark C; Wang, Shaoli; Chen, Gong; Xie, Wen; Wu, Qingjun; Wang, Wenkai; Zhang, Youjun
Plants frequently engage in simultaneous interactions with diverse classes of biotic antagonists. Differential induction of plant defence pathways by these antagonists, and interactions between pathways, can have important ecological implications; however, these effects are currently not well understood. We explored how Tomato yellow leaf curl virus (TYLCV) influenced the performance of its vector (Bemisia tabaci) and a non-vector herbivore (Tetranychus urticae) occurring separately or together on tomato plants (Solanum lycopersicum). TYLCV enhanced the performance of B. tabaci, although this effect was statistically significant only in the absence of T. urticae, which adversely affected B. tabaci performance regardless of infection status. In contrast, the performance of T. urticae was enhanced (only) by the combined presence of TYLCV and B. tabaci. Analyses of phytohormone levels and defence gene expression in wild-type tomatoes and various plant-defence mutants indicate that the enhancement of herbivore performance (for each species) entails the disruption of downstream defences in the jasmonic acid (JA) pathway. For T. urticae, this disruption appears to involve antagonistic effects of salicylic acid (SA), which is cumulatively induced to high levels by B. tabaci and TYLCV. In contrast, TYLCV was found to suppress JA-mediated responses to B. tabaci via mechanisms independent of SA. PMID:26436779
Simonenko, V B; Abashin, V G; Polovinka, V S
The article is devoted to activity of the Central Military Hospital of the People's Commissariat for Defence during the Great Patriotic War. The research is based on declassified orders of PCD and orders of the chef of hospital. Authors presented the role of the hospital in organization of medical aid for officers of PCD, members of their families, Red Army soldiers, junior and senior Red Army commanders; the role of the hospital in organization of medical facilities for combat army; medical supply for evacuation of family members of PCD's officers ( en route and in evacuation places); delivery of child health care to children of officers of PCD in the hospital and education in kindergartens of PCD. PMID:25286563
Full Text Available In this paper we argue for a human-in-the-loop approach to the study of situation awareness in computer defence analysis (CDA. The cognitive phenomenon of situation awareness (SA has received significant attention in cybersecurity/CDA research. Yet little of this work has attended to the cognitive aspects of situation awareness in the CDA context; instead, the human operator has been treated as an abstraction within the larger human-technology system. A more human-centric approach that seeks to understand the socio-cognitive work of human operators as they perform CDA will yield greater insights into the design of tools and interfaces for CDA. As support for this argument, we present our own work employing the Living Lab Framework through which we ground our experimental findings in contextual knowledge of real-world practice.
This paper describes the design of the advanced nuclear power plant ACP1000 in China that keeps the principle of defence in depth. To enhance the safety of the new generation NPPs, passive and active engineering safety features are used. The reactor will be kept safe under design basis accidents by using active engineering safety features, such as the medium and low pressure safety injection systems, and the emergency feedwater system. Under beyond DBAs, the passive safety systems will be actuated to keep removing residual heat for more than 72 hours, and to keep the core melt retained and cooled in the vessel. After the Fukushima nuclear accident, there are six main design enhancements in ACP1000 to meet the demands of the China authorities. (author)
Two-hundred-fifty white male Wistar rats were poisoned with a daily dose of 1/100 LD50 paraquat water solution, five days weekly, over a period of 4 months. Immediately after that the animals were exposed to a single whole-body irradiation with a dose rate of 2 and 4 Gy on a linear accelerator with photon energy 9 MeV and radiation power 2 Gy/min. The biological effects of the isolated and combined two factors on the pulmonary antioxidant defence mechanisms were studied from the 1st up to the 60th post-irradiation days. It was established that paraquat and ionizing radiation inhibited the enzyme activity of superoxide dismutase, catalase and glucose-6-phosphate dehydrogenase and decreased the content of non-protein weight groups in lung homogenate at an early stage. The combined application of both factors had a significant synergic effect