Long term expression of bicistronic vector driven by the FGF-1 IRES in mouse muscle
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Van den Berghe Loïc
2007-10-01
Full Text Available Abstract Background Electrotransfer of plasmid DNA into skeletal muscle is a promising strategy for the delivery of therapeutic molecules targeting various muscular diseases, cancer and lower-limb ischemia. Internal Ribosome Entry Sites (IRESs allow co-expression of proteins of interest from a single transcriptional unit. IRESs are RNA elements that have been found in viral RNAs as well as a variety of cellular mRNAs with long 5' untranslated regions. While the encephalomyocarditis virus (EMCV IRES is often used in expression vectors, we have shown that the FGF-1 IRES is equally active to drive short term transgene expression in mouse muscle. To compare the ability of the FGF-1 IRES to drive long term expression against the EMCV and FGF-2 IRESs, we performed analyses of expression kinetics using bicistronic vectors that express the bioluminescent renilla and firefly luciferase reporter genes. Long term expression of bicistronic vectors was also compared to that of monocistronic vectors. Bioluminescence was quantified ex vivo using a luminometer and in vivo using a CCD camera that monitors luminescence within live animals. Results Our data demonstrate that the efficiency of the FGF-1 IRES is comparable to that of the EMCV IRES for long term expression of bicistronic transgenes in mouse muscle, whereas the FGF-2 IRES has a very poor activity. Interestingly, we show that despite the global decrease of vector expression over time, the ratio of firefly to renilla luciferase remains stable with bicistronic vectors containing the FGF-1 or FGF-2 IRES and is slightly affected with the EMCV IRES, whereas it is clearly unstable for mixed monocistronic vectors. In addition, long term expression more drastically decreases with monocistronic vectors, and is different for single or mixed vector injection. Conclusion These data validate the use of bicistronic vectors rather than mixed monocistronic vectors for long term expression, and support the use of the
Construction and expression of the bicistronic expression vector with RANTES and SDF-1 genes
Institute of Scientific and Technical Information of China (English)
张颖; 白雪帆; 李谨革; 黄长形; 孙永涛; 聂青和; 王九平
2003-01-01
Objective:To construct bicistronic expression vector with RANTES and SDF-1 genes,the ligands of HIV 1 principal coreceptors,and identify its expression.Methods:RANTES-KDEL was amplified from plasmid pCMV-R-K by PCR and cloned into eukaryotic expression vector pCMV-S/K.Gene transfection into HeLa cells was carried out by lipofectin.Indirect immumofluorescence and radioimmunoprecipitation were used to confirm the expression of RANTES and SDF-1.Results:The construction of pCMV-R-K-S-K was confirmed by enzymatic digestion and sequencing.RANTES and SDF-1 were shown expressed in HeLa cells by indirect immumofluorescence and radioimmunoprecipitation.Conclusion:pCMV-R-K-S-K was constructed and expressed in cell line Hela successfully,which will contribute to further study of gene therapy of AIDS by HIV-1 coreceptors knockout.
Hutson, Thomas Haynes; Kathe, Claudia; Menezes, Sean Christopher; Rooney, Marie-Claire; Bueler, Hansruedi; Moon, Lawrence David Falcon
2014-01-01
Recombinant adeno-associated viral (AAV) vectors are one of the most promising therapeutic delivery systems for gene therapy to the central nervous system (CNS). Preclinical testing of novel gene therapies requires the careful design and production of AAV vectors and their successful application in a model of CNS injury. One major limitation of AAV vectors is their limited packaging capacity (genes (e.g., from two promoters) difficult. An internal ribosomal entry site has been used to express two genes: However, the second transgene is often expressed at lower levels than the first. In addition to this, achieving high levels of transduction in the CNS can be challenging. In this chapter we describe the cloning of a bicistronic AAV vector that uses the foot-and-mouth disease virus 2A sequence to efficiently express two genes from a single promoter. Bicistronic expression of a therapeutic gene and a reporter gene is desirable so that the axons from transduced neurons can be tracked and, after CNS injury, the amount of axonal sprouting or regeneration quantified. We go on to describe how to perform a pyramidotomy model of CNS injury and the injection of AAV vectors into the sensorimotor cortex to provide efficient transduction and bicistronic gene expression in cortical neurons such that transduced axons are detectable in the dorsal columns of the spinal cord.
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Ottobrini, Luisa; Lecchi, Michela; Martelli, Cristina; Lucignani, Giovanni [University of Milan, Unit of Nuclear Medicine, Hospital San Paolo, Institute of Radiological Sciences, Milan (Italy); Ciana, Paolo; Maggi, Adriana [University of Milan, Department of Pharmacological Sciences, Milan (Italy); Moresco, Rosamaria; Belloli, Sara; Todde, Sergio; Fazio, Ferruccio [University of Milan-Bicocca, Scientific Institute H. S. Raffaele, CNR-IBFM, Milan (Italy); Gambhir, Sanjiv S. [Stanford University, Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Bio-X Program, Stanford, CA (United States)
2008-02-15
The aim of this study was to develop a cellular model for the concurrent imaging of reporter genes expression by using positron emission tomography (PET) and bioluminescence imaging (BLI) for the assessment of estrogen receptor activity in vivo in a breast cancer model. Two reporters were chosen: a mutated form of the dopaminergic D2 receptor (D{sub 2}R80A) for PET imaging, and the Firefly Luciferase for BLI. The presence of an IRES sequence between the two reporters ensured the coordinated expression driven by the same regulatory sequence containing an estrogen responsive element (ERE). To prevent chromatin effects on reporter expression, the construct was flanked by insulator sequences (Matrix Attachment Region, MAR). In vitro studies showed that the vector was efficient in coordinating the expression of the two genes. Moreover, stably transfected cells implanted in recipient animals maintained their capacity to express the reporters and react to systemic treatments permitting the in vivo study of ERs activity by PET and BLI imaging. In vitro expression analysis after long-term treatments showed different behaviour of the two reporter proteins in monitoring estrogen-dependent transcription outlining the importance of multi-reporter systems. With this model, PET and BLI can be applied to the concurrent evaluation of gene expression induced by estrogen and its analogues by using a bicistronic construct. The combined features of rapid, sensitive, sequential BLI and tomographic and quantitative PET imaging will allow the use of this strategy for the in vivo evaluation of molecular processes also for pharmacodynamic studies. (orig.)
Construction and Expression Efficiency of Bicistronic Expression Vector DV%双顺反子表达载体DV的构建及其表达效率
Institute of Scientific and Technical Information of China (English)
张丽星; 张喜珍; 王玉倩; 刘晨露; 夏秋; 孔维; 于湘晖; 张海红
2011-01-01
Objective To construct a bicistronic expression vector DV and determine its expression efficiency. Methods BGH gene and promoter CMV-intronA gene fragments were amplified by PCR using vector VR1012 as a template, and inserted into the corresponding sites between promoter and terminator of vector VR1012 to construct bicistronic expression vector DV. Luciferase gene fragment as a report gene was amplified by PCR using plasmid pshuttle-luciferase as a template and cloned into vector DV behind the two promoters respectively to obtain new vectors DV-lucl and DV-luc2. COS-7 cells were transfected with DV-lucl, DV-Iuc2 and pshuttle-luciferase respectively, then determined for the expression levels of luciferase by Western blot and the ability of luciferase in substrate degradation by enzyme-labeled fluorescent apparatus. Results Restriction analysis proved that bicistronic expression vector DV was constructed correctly. Luciferase was expressed in both the COS-7 cells transfected with DV-lucl and DV-Iuc2, while the expression efficiencies in the latter was slightly higher than that in the former. Conclusion Bicistronic expression vector DV was successfully constructed, of which the priming efficiency of promoter 2 was slightly higher than that of promoter 1. It laid a foundtion of studies on gene therapy, transcriptional regulation and multivalent vaccine.%目的 构建双顺反子表达载体DV,并检测其表达效率.方法 以载体VR1012为模板,PCR扩增BGH基因和启动子CMV-intronA基因片段,分别连接至载体VR1012启动子和终止子之间的相应位点上,构建双顺反子表达载体DV.另以质粒pshuttle-luciferase为模板,PCR扩增报告基因luciferase片段,分别连接至DV的两个启动子后,得到质粒DV-luc1和DVluc2.将质粒DV-luc1、DV-luc2和阳性质粒pshuttle-luciferase分别转染COS-7细胞,Western blot检测lucfferase蛋白的表达情况,荧光酶标仪检测luciferase降解底物的水平.结果 双顺反子表达载体DV
Puntel, Mariana; Muhammad, A K M G; Candolfi, Marianela; Salem, Alireza; Yagiz, Kader; Farrokhi, Catherine; Kroeger, Kurt M; Xiong, Weidong; Curtin, James F; Liu, Chunyan; Bondale, Niyati S; Lerner, Jonathan; Pechnick, Robert N; Palmer, Donna; Ng, Philip; Lowenstein, Pedro R; Castro, Maria G
2010-06-01
Glioblastoma multiforme (GBM) is a deadly primary brain tumor. Conditional cytotoxic/immune-stimulatory gene therapy (Ad-TK and Ad-Flt3L) elicits tumor regression and immunological memory in rodent GBM models. Since the majority of patients enrolled in clinical trials would exhibit adenovirus immunity, which could curtail transgene expression and therapeutic efficacy, we used high-capacity adenovirus vectors (HC-Ads) as a gene delivery platform. Herein, we describe for the first time a novel bicistronic HC-Ad driving constitutive expression of herpes simplex virus type 1 thymidine kinase (HSV1-TK) and inducible Tet-mediated expression of Flt3L within a single-vector platform. We achieved anti-GBM therapeutic efficacy with no overt toxicities using this bicistronic HC-Ad even in the presence of systemic Ad immunity. The bicistronic HC-Ad-TK/TetOn-Flt3L was delivered into intracranial gliomas in rats. Survival, vector biodistribution, neuropathology, systemic toxicity, and neurobehavioral deficits were assessed for up to 1 year posttreatment. Therapeutic efficacy was also assessed in animals preimmunized against Ads. We demonstrate therapeutic efficacy, with vector genomes being restricted to the brain injection site and an absence of overt toxicities. Importantly, antiadenoviral immunity did not inhibit therapeutic efficacy. These data represent the first report of a bicistronic vector platform driving the expression of two therapeutic transgenes, i.e., constitutive HSV1-TK and inducible Flt3L genes. Further, our data demonstrate no promoter interference and optimum gene delivery and expression from within this single-vector platform. Analysis of the efficacy, safety, and toxicity of this bicistronic HC-Ad vector in an animal model of GBM strongly supports further preclinical testing and downstream process development of HC-Ad-TK/TetOn-Flt3L for a future phase I clinical trial for GBM.
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Calvo, Fernanda Bernardes
2009-07-01
Gene therapy has been used in preclinical studies and clinical trials in order to alleviate or cure a disease. Retroviral vectors are a tool for gene transfer is widely used. Bicistronic vectors are an attractive alternative for treatment of complex diseases. A variety of options exists to simultaneously express two genes in genetically modified cells. The most common approach relies on bicistronic vectors in which the genes are linked to each other by an internal ribosome entry site allowing co-translational expression of both cistrons. Endostatin, the C-terminal fragment of collagen XVIII, is a potent angiogenesis inhibitor. At present, ES has been widely used in anti-angiogenic in a variety of experimental tumor models, and clinical trials to test it as an anti-tumor agent are already under way. Immunotherapy has been used as adjuvant treatment for tumors and has been used in several preclinical studies and clinical trials. The objective of this project was to construct and characterize 'in vitro' an IRES-based bicistronic retroviral vector encoding endostatin and interleukin-2. The construction of the vector was performed in three stages, the final construction was analyzed by restriction analysis and sequencing. Packaging cells were prepared. The endostatin and interleukin-2 levels were determined by Dot blot. Monocistronic and bicistronic mRNA expression were analyzed by real time RT-PCR. Bicistronic vector showed high levels of virus trites, ranging from 4.20x10{sup 5} to 1.53x10{sup 6}UFC/ml. Secreted levels of endostatin and interleukin-2 ranged from 1.08 to 2.08{mu}g/10{sup 6}cells.24h and 0.66 - 0.89{mu}g/10{sup 6}cells.24h, respectively. The mRNA expression of ES in the NIH3T3 clone pLend-IRES-IL2SN was 2 times higher than the level presented by the NIH3T3 clone pLendSN. The endostatin promoted inhibition (40%) of endothelial cell proliferation. Interleukin-2 promoted a proliferation of 10.6% lymphocytes CD4 and 8.9% of CD8. We conclude that
Institute of Scientific and Technical Information of China (English)
马小松; 王英振; 王昌耀; 刘金钊
2011-01-01
Objective: To construct a bicistronic eukayotic expression vector pIRES-BMP2-TGF. Methods: The BMP2 gene was obtained from pGEMT/BMP2 plasmid by PCR. And it was inserted into bicistronic eukaryotic expression plasmid vector pIRES. The TGFP 3 was extracted from human embryonal tissue by RT-PCR, then the gene was inserted into the plasmid pIRES-BMP2. The inserted target genes in the plasmid were detected by restriction enzyme digestion and nucleotide sequencing. Results: The direction and sequences of the new bicistronic eukaryotic expression vector pIRES-BMP2-TGFβ3 were correct. Conclusion: The bicistronic eukaryotic expression vector was successfully constructed.%目的:构建与鉴定骨形态发生蛋白BMP2和转化生长因子TGFβ3双基因真核表达载体pIRES-BMP2-TGFβ3.方法:首先,用PCR方法从质粒pGEMT/BMP2中扩增出BMP2基因全长,并将其连入双基因真核表达载体pIRES,得到质粒pIRES-BMP2,其次,从人胚胎组织提取总RNA,反转录成cDNA,以反转录的cDNA为模板,PCR扩增出TGFβ3基因全长,将TGFβ3基因连入质粒pIRES-BMP2;用酶切的方法筛选出阳性重组质粒,并进行测序鉴定.结果:酶切鏊定证明已将BMP2和TGFβ3两个基因连入载体中,测序结果完全正确.结论:成功构建PIRES-BMP2/TGFβ3双基因真核表达载体.
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Puntel, Mariana [Department of Neurosurgery, The University of Michigan School of Medicine, MSRB II, RM 4570C, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689 (United States); Department of Cell and Developmental Biology, The University of Michigan School of Medicine, MSRB II, RM 4570C, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689 (United States); Gene Therapeutics Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048 (United States); Ghulam, Muhammad A.K.M. [Gene Therapeutics Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048 (United States); Farrokhi, Catherine [Department of Psychiatry and Behavioral Neurosciences, Cedars Sinai Medical Center, Los Angeles, CA 90048 (United States); VanderVeen, Nathan; Paran, Christopher; Appelhans, Ashley [Department of Neurosurgery, The University of Michigan School of Medicine, MSRB II, RM 4570C, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689 (United States); Department of Cell and Developmental Biology, The University of Michigan School of Medicine, MSRB II, RM 4570C, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689 (United States); Kroeger, Kurt M.; Salem, Alireza [Gene Therapeutics Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048 (United States); Lacayo, Liliana [Department of Psychiatry and Behavioral Neurosciences, Cedars Sinai Medical Center, Los Angeles, CA 90048 (United States); Pechnick, Robert N. [Department of Psychiatry and Behavioral Neurosciences, Cedars Sinai Medical Center, Los Angeles, CA 90048 (United States); Department of Psychiatry and Behavioral Neurosciences, David Geffen School of Medicine, University of California, Los Angeles, CA (United States); Kelson, Kyle R.; Kaur, Sukhpreet; Kennedy, Sean [Gene Therapeutics Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048 (United States); Palmer, Donna; Ng, Philip [Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030 (United States); and others
2013-05-01
Adenoviral vectors (Ads) are promising gene delivery vehicles due to their high transduction efficiency; however, their clinical usefulness has been hampered by their immunogenicity and the presence of anti-Ad immunity in humans. We reported the efficacy of a gene therapy approach for glioma consisting of intratumoral injection of Ads encoding conditionally cytotoxic herpes simplex type 1 thymidine kinase (Ad-TK) and the immunostimulatory cytokine fms-like tyrosine kinase ligand 3 (Ad-Flt3L). Herein, we report the biodistribution, efficacy, and neurological and systemic effects of a bicistronic high-capacity Ad, i.e., HC-Ad-TK/TetOn-Flt3L. HC-Ads elicit sustained transgene expression, even in the presence of anti-Ad immunity, and can encode large therapeutic cassettes, including regulatory elements to enable turning gene expression “on” or “off” according to clinical need. The inclusion of two therapeutic transgenes within a single vector enables a reduction of the total vector load without adversely impacting efficacy. Because clinically the vectors will be delivered into the surgical cavity, normal regions of the brain parenchyma are likely to be transduced. Thus, we assessed any potential toxicities elicited by escalating doses of HC-Ad-TK/TetOn-Flt3L (1 × 10{sup 8}, 1 × 10{sup 9}, or 1 × 10{sup 10} viral particles [vp]) delivered into the rat brain parenchyma. We assessed neuropathology, biodistribution, transgene expression, systemic toxicity, and behavioral impact at acute and chronic time points. The results indicate that doses up to 1 × 10{sup 9} vp of HC-Ad-TK/TetOn-Flt3L can be safely delivered into the normal rat brain and underpin further developments for its implementation in a phase I clinical trial for glioma. - Highlights: ► High capacity Ad vectors elicit sustained therapeutic gene expression in the brain. ► HC-Ad-TK/TetOn-Flt3L encodes two therapeutic genes and a transcriptional switch. ► We performed a dose escalation study at
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Bahrami, Shervin; Pedersen, Finn Skou; Duch, Mogens R.
2003-01-01
The envelope protein of retroviruses is responsible for viral entry into host cells. Here, we describe a mutational library approach to dissect functional domains of the envelope protein involving a retroviral vector, which expresses both the envelope protein of Akv murine leukemia virus (MLV...... mutational library of Arg 85 and Asp 86 in the first variable region of Akv envelope protein. Homologous amino acids to Asp 86 in Moloney and Friend murine leukemia viruses are thought to be directly involved in receptor binding. Subsequent selection of mutants capable of infecting murine NIH 3T3 cells...... indicated that the wild type aspartic acid or another hydrophilic residue at position 86 is an important determinant for envelope function....
Viral miRNA targeting of bicistronic and polycistronic transcripts.
Zhu, Ying; Huang, Yufei; Jung, Jae U; Lu, Chun; Gao, Shou-Jiang
2014-08-01
Successful viral infection entails a choreographic regulation of viral gene expression program. Kaposi's sarcoma-associated herpesvirus (KSHV) encodes numerous miRNAs that regulate viral life cycle. However, few viral targets have been identified due to the lack of information on KSHV 3' untranslated regions (3'UTRs). Recent genome-wide mapping of KSHV transcripts and 3'UTRs has revealed abundant bicistronic and polycistronic transcripts. The extended 3'UTRs of the 5' proximal genes of bicistronic and polycistronic transcripts offer additional regulatory targets. Indeed, a genome-wide screening of KSHV 3'UTRs has identified several bicistronic and polycistronic transcripts as the novel targets of viral miRNAs. Together, these works have expanded our knowledge of the unique features of KSHV gene regulation program and provided valuable resources for the research community.
Construction and Co-expression of Bicistronic Plasmid Encoding Human WEE1 and Stem Cell Factor
Institute of Scientific and Technical Information of China (English)
Ping LEI; Wen-Han LI; Wen-Jun LIAO; Bing YU; Hui-Fen ZHU; Jing-Fang SHAO; Guan-Xin SHEN
2005-01-01
To protect the hematopoietic stem cells (HSCs) from apoptosis induced by chemotherapy and promote HSC proliferation, bi-functional gene delivery systems are increasingly investigated in gene therapy.In the present study, we constructed a bicistronic vector, pWISG, expressing the anti-apoptotic protein human WEE1 (WEE1Hu) and the fusion protein of the proliferation-stimulating stem cell factor (SCF) and enhanced green fluorescent protein (EGFP) separately with internal ribosome entry site (IRES). We first examined the expression and location of WEE1Hu in Chinese hamster ovary (CHO) cells and showed that WEE1Hu was located in the nucleus, which was confirmed by immunohistochemistry and Western blot. We determined the expression and receptor-binding ability of the SCF-EGFP fusion protein on CD34+ cells,which were proved by reverse transcription polymerase chain reaction (RT-PCR) and flow cytometry,respectively. Furthermore, inhibition of cisplatin-induced apoptosis was observed in CD34+ cells transfected with pWISG, which implies that protection for CD34+ cells was achieved via WEE1Hu and SCF-EGFP. Our study suggests that the introduction of two functional genes via bicistronic vector is more powerful and efficient than single gene therapy.
Yero, Daniel; Pajón, Rolando; Niebla, Olivia; Sardiñas, Gretel; Vivar, Isbel; Perera, Yasser; García, Darien; Delgado, Maité; Cobas, Karem
2006-04-01
In the post-genomic era, every aspect of the production of proteins must be accelerated. In this way, several vectors are currently exploited for rapid production of recombinant proteins in Escherichia coli. N-terminal fusions to the first 47 amino acids of the LpdA (dihydrolipoamide dehydrogenase A) protein of Neisseria meningitidis have been shown to increase the expression of recombinant proteins. Consequently, we have constructed a modified N-terminal LpdA fusion vector, introducing the blue/white colony selection by exploiting a bicistronic gene organization. In the new vector, the sequence encoding the first 47 amino acids of meningococcal LpdA and the alpha-peptide sequence of beta-galactosidase were connected via a ribosome-binding site, and two MCSs (multiple cloning sites) were located surrounding the latter, allowing efficient cloning by colour selection of recombinants. The vector was also improved with the addition of a C-terminal polyhistidine tag, and an EKS (enterokinase recognition sequence) immediately after the LpdA fusion sequence. The new plasmid was employed in the expression and purification of six different bacterial polypeptides. One of these recombinant proteins, P6 protein from Haemophilus influenzae, was used as a model and its N-terminal fusion sequence was totally removed from the recombinant version after incubation with the enterokinase protease, while the polyhistidine tail successfully allowed the purification of the unfused protein from the protease reaction. Two completely new neisserial vaccine candidates, NMB0088 and NMB1126 proteins, were cloned, expressed and purified using this system. To our knowledge, this constitutes the first report of the cloning and expression of these proteins in E. coli.
2016-01-01
Documento que contiene la explicación sobre las temáticas de Sistemas coordenados, Cantidades vectoriales y escalares, Algunas propiedades de los vectores, Componentes de un vector y vectores unitarios
DEFF Research Database (Denmark)
Boeriis, Morten; van Leeuwen, Theo
2017-01-01
This article revisits the concept of vectors, which, in Kress and van Leeuwen’s Reading Images (2006), plays a crucial role in distinguishing between ‘narrative’, action-oriented processes and ‘conceptual’, state-oriented processes. The use of this concept in image analysis has usually focused...... on the most salient vectors, and this works well, but many images contain a plethora of vectors, which makes their structure quite different from the linguistic transitivity structures with which Kress and van Leeuwen have compared ‘narrative’ images. It can also be asked whether facial expression vectors...... should be taken into account in discussing ‘reactions’, which Kress and van Leeuwen link only to eyeline vectors. Finally, the question can be raised as to whether actions are always realized by vectors. Drawing on a re-reading of Rudolf Arnheim’s account of vectors, these issues are outlined...
Institute of Scientific and Technical Information of China (English)
马小松; 刘金钊; 王昌耀; 王英振; 刘世海; 刘相萍
2011-01-01
[目的]构建骨形态发生蛋白BMP2和转化生长因子TGFβ3双基因真核表达载体.[方法]从人胚胎组织提取总RNA,反转录成cDNA,以pGEMT/BMP2和反转录的cDNA为模板,PCR扩增出BMP2和TGFβ3两个基因全长,将两个基因片段分别定向连入双基因真核表达载体pIRES;用酶切的方法筛选出阳性重组质粒,并进行测序鉴定.[结果]酶切鉴定证明已将BMP2和TGFβ3两个基因连入载体中,测序结果完全正确.[结论]成功构建pIRESBMP2/TGFβ3双基因真核表达载体.%[ Objective]To construct a bicistronic eukayotic expression plasmid consisting of BMP2 and TGFβ3 target genes.[ Method ] The DNA fragment of BMP2 and TGFβ3 genes were obtained from pGEMT/BMP2 plasmid and human embryonal tissue by PCR, respectively. They were inserted into bicistronic eukaryotic expression plasmid vector plRES. The inserted target genes in the plasmid were verified by restriction enzyme digestion and nucleotide sequencing. [ Result ] The direction and sequences of the new bicistronic eukaryotic expression plasmid pIRES - BMP2 -TGFβ3 were correct. [ Conclusion] The bicistronic eukaryotic expression plasmid has been constructed successfully.
Kemnade, Jan Ole; Seethammagari, Mamatha; Narayanan, Priya; Levitt, Jonathan M; McCormick, Alison A; Spencer, David M
2012-07-01
Recent modest successes in ex vivo dendritic cell (DC) immunotherapy have motivated continued innovation in the area of DC manipulation and activation. Although ex vivo vaccine approaches continue to be proving grounds for new DC manipulation techniques, the intrinsic limits of ex vivo therapy, including high cost, minimal standardization, cumbersome delivery, and poor accessibility, incentivizes the development of vaccines compatible with in vivo DC targeting. We describe here a method to co-deliver both tumor-specific antigen (TSA) and an iMyD88/CD40 adjuvant (iMC), to DCs that combines toll-like receptor (TLR) and CD40 signaling. In this study, we demonstrate that simple TSA delivery via adenoviral vectors results in strong antitumor immunity. Addition of iMC delivered in a separate vector is insufficient to enhance this effect. However, when delivered simultaneously with TSA in a single bicistronic vector (BV), iMC is able to significantly enhance antigen-specific cytotoxic T-cell (CTL) responses and inhibit established tumor growth. This study demonstrates the spatial-temporal importance of concurrent DC activation and TSA presentation. Further, it demonstrates the feasibility of in vivo molecular enhancement of DCs necessary for effective antitumor immune responses.
Use of the viral 2A peptide for bicistronic expression in transgenic mice
Directory of Open Access Journals (Sweden)
Trichas Georgios
2008-09-01
Full Text Available Abstract Background Transgenic animals are widely used in biomedical research and biotechnology. Multicistronic constructs, in which several proteins are encoded by a single messenger RNA, are commonly used in genetically engineered animals. This is currently done by using an internal ribosomal entry site to separate the different coding regions. 2A peptides result in the co-translational 'cleavage' of proteins and are an attractive alternative to the internal ribosomal entry site. They are more reliable than the internal ribosomal entry site and lead to expression of multiple cistrons at equimolar levels. They work in a wide variety of eukaryotic cells, but to date have not been demonstrated to function in transgenic mice in an inheritable manner. Results To test 2A function in transgenic mice and uncover any possible toxicity of widespread expression of the 2A peptide, we made a bicistronic reporter construct containing the coding sequence for a membrane localised red fluorescent protein (Myr-TdTomato and a nuclear localised green fluorescent protein (H2B-GFP, separated by a 2A sequence. When this reporter is transfected into HeLa cells, the two fluorescent proteins correctly localise to mutually exclusive cellular compartments, demonstrating that the bicistronic construct is a reliable readout of 2A function. The two fluorescent proteins also correctly localise when the reporter is electroporated into chick neural tube cells. We made two independent transgenic mouse lines that express the bicistronic reporter ubiquitously. For both lines, transgenic mice are born in Mendelian frequencies and are found to be healthy and fertile. Myr-TdTomato and H2B-GFP segregate to mutually exclusive cellular compartments in all tissues examined from a broad range of developmental stages, ranging from embryo to adult. One transgenic line shows X-linked inheritance of the transgene and mosaic expression in females but uniform expression in males, indicating
DEFF Research Database (Denmark)
Boldyreff, B; James, P; Staudenmann, W;
1993-01-01
Human casein kinase-2 (CK-2) subunits alpha and beta were bicistronically expressed in bacteria. The recombinant holoenzyme shared all investigated properties with the native CK-2 from mammalian sources (rat liver, Krebs II mouse ascites tumour cells). Contrary to recombinant human CK-2 produced...
Leandro, João; Leandro, Paula; Flatmark, Torgeir
2011-05-01
Hybrid forms of human phenylalanine hydroxylase (hPAH) mutants have been found to present catalytic activities lower than predicted from the individual recombinant forms, indicating that interallelic complementation could be a major determinant of the metabolic phenotype of compound heterozygous phenylketonuric (PKU) patients. To provide a molecular explanation for interallelic complementation we have here developed a bicistronic expression system and a purification strategy to obtain isolated hPAH heteromeric forms. On co-expression of WT-hPAH (~50% tetramer; ~10% dimer) and the N- and C-terminally truncated form ΔN102/ΔC24-hPAH (~80% dimer) no heterodimers were recovered. Moreover, by co-expression of WT-hPAH and the N-terminally truncated form ΔN102-hPAH (~95% tetramer), heterotetramers, as a result of an assembly of two different homodimers, were isolated. The recovered (WT)/(ΔN102)-hPAH heterotetramers revealed a catalytic activity deviating significantly from that calculated by averaging the respective recombinant homotetrameric forms. The heterotetramer assembly also results in conformational changes in the WT-hPAH protomer, as detected by trypsin limited proteolysis. The finding that the presence of two homodimers with different kinetic parameters influences the properties of the resulting heterotetrameric protein indicates that the dimers exhibit interactions which are transmitted across the assembled tetramer. The bicistronic expression system developed here allowed the isolation of hybrid forms that exhibit negative interallelic complementation, and may represent a model system for studying the molecular pathogenic mechanisms of PAH gene mutations in compound heterozygous PKU patients, providing the rationale to understand the observed inconsistencies both in genotype/phenotype correlations and in the response to BH(4) supplementation.
Nador, R G; Milligan, L L; Flore, O; Wang, X; Arvanitakis, L; Knowles, D M; Cesarman, E
2001-08-15
Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) encodes a G protein-coupled receptor (vGPCR) in open reading frame (ORF) 74, which is homologous to human chemokine receptors. KSHV vGPCR is constitutively active and induces VEGF-mediated angiogenesis. Previous studies have shown that ORF 74 is transcribed as part of a bicistronic message containing ORF K14 upstream of ORF 74, with an early lytic pattern of expression. We have now extended these studies by analyzing three different KSHV-positive primary effusion lymphoma (PEL) cell lines and three PEL clinical samples. In addition, we have identified another less abundant monocistronic transcript containing only ORF 74. Both transcripts were identified at low but similar levels in two PEL clinical samples. We evaluated the degree of sequence and functional conservation of ORF74 in three additional PELs and two KS clinical specimens, demonstrating complete identity at the amino acid level among all isolates. While it is expressed as an early lytic transcript in PEL cell lines, in primary clinical PEL samples transcription of KSHV vGPCR can be readily detected.
Rice black-streaked dwarf virus genome segment S5 is a bicistronic mRNA in infected plants.
Yang, Jian; Zhang, Heng-Mu; Ying, Lu; Li, Jing; Lv, Ming-Fang; Xie, Li; Li, Pei-Pei; Liu, Xiao-Ya; Liang-Ying, Dai; Chen, Jian-Ping
2014-02-01
Rice black-streaked dwarf virus (RBSDV) is a recognized member of the genus Fijivirus, family Reoviridae. Genome segment S5 has a putative second ORF partially overlapping the major ORF but in a different reading frame. This putative ORF is present in a published sequence and in two Chinese isolates now sequenced. Antibodies were raised against purified P5-1 and P5-2 fusion proteins expressed in a prokaryotic system. In western blots, these antibodies reacted with proteins of about 106 and 27 kDa, respectively, as predicted by sequence analysis. In immunoelectron microscopy, antibodies to P5-1 reacted with viroplasms, indicating that P5-1 is a component of viroplasms, but no labeling was observed with P5-2 antisera. Northern blot assays showed that the genome segment S5 was transcribed as a single mRNA with no subgenomic RNA. These results show that S5 is functionally bicistronic in infected plants. Possible translational mechanisms for P5-2 are discussed.
Spatz, Stephen J; Volkening, Jeremy D; Mullis, Robert; Li, Fenglan; Mercado, John; Zsak, Laszlo
2013-10-01
Meleagrid herpesvirus type 1 (MeHV-1) is an ideal vector for the expression of antigens from pathogenic avian organisms in order to generate vaccines. Chicken parvovirus (ChPV) is a widespread infectious virus that causes serious disease in chickens. It is one of the etiological agents largely suspected in causing Runting Stunting Syndrome (RSS) in chickens. Initial attempts to express the wild-type gene encoding the capsid protein VP2 of ChPV by insertion into the thymidine kinase gene of MeHV-1 were unsuccessful. However, transient expression of a codon-optimized synthetic VP2 gene cloned into the bicistronic vector pIRES2-Ds-Red2, could be demonstrated by immunocytochemical staining of transfected chicken embryo fibroblasts (CEFs). Red fluorescence could also be detected in these transfected cells since the red fluorescent protein gene is downstream from the internal ribosome entry site (IRES). Strikingly, fluorescence could not be demonstrated in cells transiently transfected with the bicistronic vector containing the wild-type or non-codon-optimized VP2 gene. Immunocytochemical staining of these cells also failed to demonstrate expression of wild-type VP2, indicating that the lack of expression was at the RNA level and the VP2 protein was not toxic to CEFs. Chickens vaccinated with a DNA vaccine consisting of the bicistronic vector containing the codon-optimized VP2 elicited a humoral immune response as measured by a VP2-specific ELISA. This VP2 codon-optimized bicistronic cassette was rescued into the MeHV-1 genome generating a vectored vaccine against ChPV disease.
Remarkable stability of an instability-prone lentiviral vector plasmid in Escherichia coli Stbl3
Al-Allaf, Faisal A.; Tolmachov, Oleg E.; Zambetti, Lia Paola; Tchetchelnitski, Viktoria; Mehmet, Huseyin
2012-01-01
Large-scale production of plasmid DNA to prepare therapeutic gene vectors or DNA-based vaccines requires a suitable bacterial host, which can stably maintain the plasmid DNA during industrial cultivation. Plasmid loss during bacterial cell divisions and structural changes in the plasmid DNA can dramatically reduce the yield of the desired recombinant plasmid DNA. While generating an HIV-based gene vector containing a bicistronic expression cassette 5′-Olig2cDNA-IRES-dsRed2-3′, we encountered ...
Roche, John
1997-01-01
Suggests an approach to teaching vectors that promotes active learning through challenging questions addressed to the class, as opposed to subtle explanations. Promotes introducing vector graphics with concrete examples, beginning with an explanation of the displacement vector. Also discusses artificial vectors, vector algebra, and unit vectors.…
Hoffmann, Banesh
1975-01-01
From his unusual beginning in ""Defining a vector"" to his final comments on ""What then is a vector?"" author Banesh Hoffmann has written a book that is provocative and unconventional. In his emphasis on the unresolved issue of defining a vector, Hoffmann mixes pure and applied mathematics without using calculus. The result is a treatment that can serve as a supplement and corrective to textbooks, as well as collateral reading in all courses that deal with vectors. Major topics include vectors and the parallelogram law; algebraic notation and basic ideas; vector algebra; scalars and scalar p
Newell, Homer E
2006-01-01
When employed with skill and understanding, vector analysis can be a practical and powerful tool. This text develops the algebra and calculus of vectors in a manner useful to physicists and engineers. Numerous exercises (with answers) not only provide practice in manipulation but also help establish students' physical and geometric intuition in regard to vectors and vector concepts.Part I, the basic portion of the text, consists of a thorough treatment of vector algebra and the vector calculus. Part II presents the illustrative matter, demonstrating applications to kinematics, mechanics, and e
Directory of Open Access Journals (Sweden)
Margison Geoffrey P
2006-03-01
Full Text Available Abstract Background A number of gene therapy applications would benefit from vectors capable of expressing multiple genes. In this study we explored the feasibility and efficiency of expressing two or three transgenes in HIV-1 based lentiviral vector. Bicistronic and tricistronic self-inactivating lentiviral vectors were constructed employing the internal ribosomal entry site (IRES sequence of encephalomyocarditis virus (EMCV and/or foot-and-mouth disease virus (FMDV cleavage factor 2A. We employed enhanced green fluorescent protein (eGFP, O6-methylguanine-DNA-methyltransferase (MGMT, and homeobox transcription factor HOXB4 as model genes and their expression was detected by appropriate methods including fluorescence microscopy, flow cytometry, immunocytochemistry, biochemical assay, and western blotting. Results All the multigene vectors produced high titer virus and were able to simultaneously express two or three transgenes in transduced cells. However, the level of expression of individual transgenes varied depending on: the transgene itself; its position within the construct; the total number of transgenes expressed; the strategy used for multigene expression and the average copy number of pro-viral insertions. Notably, at limiting MOI, the expression of eGFP in a bicistronic vector based on 2A was ~4 times greater than that of an IRES based vector. Conclusion The small and efficient 2A sequence can be used alone or in combination with an IRES for the construction of multicistronic lentiviral vectors which can express encoded transgenes at functionally relevant levels in cells containing an average of one pro-viral insert.
Guzmán, F A; Distéfano, A J; Arneodo, J D; Hopp, H E; Lenardon, S L; del Vas, M; Conci, L R
2007-01-01
The nucleotide sequences of genomic segments S7 and S9 of Mal de Río Cuarto virus (MRCV, Fijivirus group II) have been determined, thus completing the entire genome sequence of the virus. These segments showed a non-overlapping bicistronic structure, as in other members of the genus. MRCV S7 ORF-1 had a length of 1086 bp and encoded a 41.5 kDa putative polypeptide, whereas MRCV S7 ORF-2 had a length of 930 bp and encoded a 36.8 kDa putative polypeptide. Proteins of 39 and 20.5 kDa were predicted for the 1014 bp long MRCV S9 ORF-1 and the 537 bp long MRCV S9 ORF-2, respectively. The terminal 5' and 3' sequences of both segments were 5'AAGUUUUU3' and 5'CAGCUnnnGUC3', respectively. Specific imperfect inverted repeats of each segment were identified. Comparison of the predicted proteins with those of related virus genome segments counterparts in maize rough dwarf virus (MRDV) and rice black streaked dwarf virus (RBSDV), showed 64.5-44.3% identities. These values are lower than those resulting from comparisons between MRDV and RBSDV. The topology of the trees obtained using the complete nucleotide and amino acid sequences of MRCV S7 and MRCV S9 was consistent with the analysis of the other MRCV segments previously published.
Komonyi, Orban; Schauer, Tamas; Papai, Gabor; Deak, Peter; Boros, Imre M
2009-03-15
Although telomere formation occurs through a different mechanism in Drosophila compared with other organisms, telomere associations result from mutations in homologous genes, indicating the involvement of similar pathways in chromosome end protection. We report here that mutations of the Drosophila melanogaster gene CG31241 lead to high frequency chromosome end fusions. CG31241 is a bicistronic gene that encodes trimethylguanosine synthase (TGS1), which forms the m3G caps of noncoding small RNAs, and a novel protein, DTL. We show that although TGS1 has no role in telomere protection, DTL is localized at specific sites, including the ends of polytene chromosomes, and its loss results in telomere associations. Mutations of ATM- and Rad3-related (ATR) kinase suppress telomere fusions in the absence of DTL. Thus, genetic interactions place DTL in an ATR-related pathway in telomere protection. In contrast to ATR kinase, mutations of ATM (ataxia telangiectasia mutated) kinase, which acts in a partially overlapping pathway of telomere protection, do not suppress formation of telomere associations in the absence of DTL. Thus, uncovering the role of DTL will help to dissect the evolutionary conserved pathway(s) controlling ATM-ATR-related telomere protection.
Wolstenholme, E Œ
1978-01-01
Elementary Vectors, Third Edition serves as an introductory course in vector analysis and is intended to present the theoretical and application aspects of vectors. The book covers topics that rigorously explain and provide definitions, principles, equations, and methods in vector analysis. Applications of vector methods to simple kinematical and dynamical problems; central forces and orbits; and solutions to geometrical problems are discussed as well. This edition of the text also provides an appendix, intended for students, which the author hopes to bridge the gap between theory and appl
Brand, Louis
2006-01-01
The use of vectors not only simplifies treatments of differential geometry, mechanics, hydrodynamics, and electrodynamics, but also makes mathematical and physical concepts more tangible and easy to grasp. This text for undergraduates was designed as a short introductory course to give students the tools of vector algebra and calculus, as well as a brief glimpse into these subjects' manifold applications. The applications are developed to the extent that the uses of the potential function, both scalar and vector, are fully illustrated. Moreover, the basic postulates of vector analysis are brou
Guilfoyle, Richard A.; Smith, Lloyd M.
1994-01-01
A vector comprising a filamentous phage sequence containing a first copy of filamentous phage gene X and other sequences necessary for the phage to propagate is disclosed. The vector also contains a second copy of filamentous phage gene X downstream from a promoter capable of promoting transcription in a bacterial host. In a preferred form of the present invention, the filamentous phage is M13 and the vector additionally includes a restriction endonuclease site located in such a manner as to substantially inactivate the second gene X when a DNA sequence is inserted into the restriction site.
Robinson, Gilbert de B
2011-01-01
This brief undergraduate-level text by a prominent Cambridge-educated mathematician explores the relationship between algebra and geometry. An elementary course in plane geometry is the sole requirement for Gilbert de B. Robinson's text, which is the result of several years of teaching and learning the most effective methods from discussions with students. Topics include lines and planes, determinants and linear equations, matrices, groups and linear transformations, and vectors and vector spaces. Additional subjects range from conics and quadrics to homogeneous coordinates and projective geom
DEFF Research Database (Denmark)
2012-01-01
for generation of a reference beam, a detector system comprising a first detector arrangement arranged in such a way that the signal beam and the reference beam are incident upon the first detector arrangement with the reference beam propagating at an angle relative to a signal beam, and wherein the first......The present invention relates to a compact, reliable and low-cost vector velocimeter for example for determining velocities of particles suspended in a gas or fluid flow, or for determining velocity, displacement, rotation, or vibration of a solid surface, the vector velocimeter comprising a laser...... assembly for emission of a measurement beam for illumination of an object in a measurement volume with coherent light whereby a signal beam emanating from the object in the measurement volume is formed in response to illumination of the object by the measurement beam, a reference beam generator...
Horikis, Theodoros P
2016-01-01
Families of soliton pairs, namely vector solitons, are found within the context of a coupled nonlocal nonlinear Schrodinger system of equations, as appropriate for modeling beam propagation in nematic liquid crystals. In the focusing case, bright soliton pairs have been found to exist provided their amplitudes satisfy a specific condition. In our analytical approach, focused on the defocusing regime, we rely on a multiscale expansion methods, which reveals the existence of dark-dark and antidark-antidark solitons, obeying an effective Korteweg-de Vries equation, as well as dark-bright solitons, obeying an effective Mel'nikov system. These pairs are discriminated by the sign of a constant that links all physical parameters of the system to the amplitude of the stable continuous wave solutions, and, much like the focusing case, the solitons' amplitudes are linked leading to mutual guiding.
Directory of Open Access Journals (Sweden)
Zihua Wang
Full Text Available Viral vectors are engineered virus variants able to deliver nonviral genetic information into cells, usually by the same routes as the parental viruses. For several virus families, replication-competent vectors carrying reporter genes have become invaluable tools for easy and quantitative monitoring of replication and infection, and thus also for identifying antivirals and virus susceptible cells. For hepatitis B virus (HBV, a small enveloped DNA virus causing B-type hepatitis, such vectors are not available because insertions into its tiny 3.2 kb genome almost inevitably affect essential replication elements. HBV replicates by reverse transcription of the pregenomic (pg RNA which is also required as bicistronic mRNA for the capsid (core protein and the reverse transcriptase (Pol; their open reading frames (ORFs overlap by some 150 basepairs. Translation of the downstream Pol ORF does not involve a conventional internal ribosome entry site (IRES. We reasoned that duplicating the overlap region and providing artificial IRES control for translation of both Pol and an in-between inserted transgene might yield a functional tricistronic pgRNA, without interfering with envelope protein expression. As IRESs we used a 22 nucleotide element termed Rbm3 IRES to minimize genome size increase. Model plasmids confirmed its activity even in tricistronic arrangements. Analogous plasmids for complete HBV genomes carrying 399 bp and 720 bp transgenes for blasticidin resistance (BsdR and humanized Renilla green fluorescent protein (hrGFP produced core and envelope proteins like wild-type HBV; while the hrGFP vector replicated poorly, the BsdR vector generated around 40% as much replicative DNA as wild-type HBV. Both vectors, however, formed enveloped virions which were infectious for HBV-susceptible HepaRG cells. Because numerous reporter and effector genes with sizes of around 500 bp or less are available, the new HBV vectors should become highly useful tools to
Rotations with Rodrigues' Vector
Pina, E.
2011-01-01
The rotational dynamics was studied from the point of view of Rodrigues' vector. This vector is defined here by its connection with other forms of parametrization of the rotation matrix. The rotation matrix was expressed in terms of this vector. The angular velocity was computed using the components of Rodrigues' vector as coordinates. It appears…
Eliezer, C J; Maxwell, E A; Sneddon, I N
1963-01-01
Concise Vector Analysis is a five-chapter introductory account of the methods and techniques of vector analysis. These methods are indispensable tools in mathematics, physics, and engineering. The book is based on lectures given by the author in the University of Ceylon.The first two chapters deal with vector algebra. These chapters particularly present the addition, representation, and resolution of vectors. The next two chapters examine the various aspects and specificities of vector calculus. The last chapter looks into some standard applications of vector algebra and calculus.This book wil
Chen, Kan; Liu, Xiang; Matsuki, Takayuki
2015-01-01
Inspired by the abundant experimental observation of axial vector states, we study whether the observed axial vector states can be categorized into the conventional axial vector meson family. In this paper we carry out analysis based on the mass spectra and two-body Okubo-Zweig-Iizuka-allowed decays. Besides testing the possible axial vector meson assignments, we also predict abundant information for their decays and the properties of some missing axial vector mesons, which are valuable to further experimental exploration of the observed and predicted axial vector mesons.
U.S. Department of Health & Human Services — VectorBase is a Bioinformatics Resource Center for invertebrate vectors. It is one of four Bioinformatics Resource Centers funded by NIAID to provide web-based...
Institute of Scientific and Technical Information of China (English)
Zhuo CHEN; Zhang Ju LIU; Yun He SHENG
2014-01-01
In this paper, we construct a category of short exact sequences of vector bundles and prove that it is equivalent to the category of double vector bundles. Moreover, operations on double vector bundles can be transferred to operations on the corresponding short exact sequences. In particular, we study the duality theory of double vector bundles in term of the corresponding short exact sequences. Examples including the jet bundle and the Atiyah algebroid are discussed.
Chen, Zhuo; Liu, Zhangju; Sheng, Yunhe
2011-01-01
In this paper, we construct a category of short exact sequences of vector bundles and prove that it is equivalent to the category of double vector bundles. Moreover, operations on double vector bundles can be transferred to operations on the corresponding short exact sequences. In particular, we study the duality theory of double vector bundles in term of the corresponding short exact sequences. Examples including the jet bundle and the Atiyah algebroid are discussed.
DEFF Research Database (Denmark)
Becciolini, Diego; Franzosi, Diogo Buarque; Foadi, Roshan;
2015-01-01
We analyze the Large Hadron Collider (LHC) phenomenology of heavy vector resonances with a $SU(2)_L\\times SU(2)_R$ spectral global symmetry. This symmetry partially protects the electroweak S-parameter from large contributions of the vector resonances. The resulting custodial vector model spectrum...
Ma, Yao; An, Huai-Jie; Wei, Xiao-Qi; Xu, Qing; Yu, Yun-Zhou; Sun, Zhi-Wei
2013-02-01
We evaluated the utility of interleukin-4 (IL-4) as molecular adjuvant of replicon vaccines for botulinum neurotoxin serotype A (BoNT/A) in mouse model. In both Balb/c and C57/BL6 mice that received the plasmid DNA replicon vaccines derived from Semliki Forest virus (SFV) encoding the Hc gene of BoNT/A (AHc), the immunogenicity was significantly modulated and enhanced by co-delivery or co-express of the IL-4 molecular adjuvant. The enhanced potencies were also produced by co-delivery or co-expression of the IL-4 molecular adjuvant in mice immunized with the recombinant SFV replicon particles (VRP) vaccines. In particular, when AHc and IL-4 were co-expressed within the same replicon vaccine vector using dual-expression or bicistronic IRES, the anti-AHc antibody titers, serum neutralization titers and survival rates of immunized mice after challenged with BoNT/A were significantly increased. These results indicate IL-4 is an effective Th2-type adjuvant for the replicon vaccines in both strain mice, and the co-expression replicon vaccines described here may be an excellent candidate for further vaccine development in other animals or humans. Thus, we described a strategy to design and develop efficient vaccines against BoNT/A or other pathogens using one replicon vector to simultaneously co-express antigen and molecular adjuvant.
2015-09-28
300001 1 of 16 VEHICLE-BASED VECTOR SENSOR STATEMENT OF GOVERNMENT INTEREST [0001] The invention described herein may be manufactured and...unmanned underwater vehicle that can function as an acoustic vector sensor . (2) Description of the Prior Art [0004] It is known that a propagating...mechanics. An acoustic vector sensor measures the particle motion via an accelerometer and combines Attorney Docket No. 300001 2 of 16 the
Directory of Open Access Journals (Sweden)
Jean-François Degbomont
2010-10-01
Full Text Available This paper addresses the symbolic representation of non-convex real polyhedra, i.e., sets of real vectors satisfying arbitrary Boolean combinations of linear constraints. We develop an original data structure for representing such sets, based on an implicit and concise encoding of a known structure, the Real Vector Automaton. The resulting formalism provides a canonical representation of polyhedra, is closed under Boolean operators, and admits an efficient decision procedure for testing the membership of a vector.
Complex Polynomial Vector Fields
DEFF Research Database (Denmark)
Dias, Kealey
vector fields. Since the class of complex polynomial vector fields in the plane is natural to consider, it is remarkable that its study has only begun very recently. There are numerous fundamental questions that are still open, both in the general classification of these vector fields, the decomposition...... or meromorphic (allowing poles as singularities) functions. There already exists a well-developed theory for iterative holomorphic dynamical systems, and successful relations found between iteration theory and flows of vector fields have been one of the main motivations for the recent interest in holomorphic...
Vectors and their applications
Pettofrezzo, Anthony J
2005-01-01
Geared toward undergraduate students, this text illustrates the use of vectors as a mathematical tool in plane synthetic geometry, plane and spherical trigonometry, and analytic geometry of two- and three-dimensional space. Its rigorous development includes a complete treatment of the algebra of vectors in the first two chapters.Among the text's outstanding features are numbered definitions and theorems in the development of vector algebra, which appear in italics for easy reference. Most of the theorems include proofs, and coordinate position vectors receive an in-depth treatment. Key concept
Advancing vector biology research
Kohl, Alain; Pondeville, Emilie; Schnettler, Esther; Crisanti, Andrea; Supparo, Clelia; Christophides, George K.; Kersey, Paul J.; Maslen, Gareth L.; Takken, Willem; Koenraadt, Constantianus J.M.; Oliva, Clelia F.; Busquets, Núria; Abad, F.X.; Failloux, Anna Bella; Levashina, Elena A.; Wilson, Anthony J.; Veronesi, Eva; Pichard, Maëlle; Arnaud Marsh, Sarah; Simard, Frédéric; Vernick, Kenneth D.
2016-01-01
Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target t
Remarkable stability of an instability-prone lentiviral vector plasmid in Escherichia coli Stbl3.
Al-Allaf, Faisal A; Tolmachov, Oleg E; Zambetti, Lia Paola; Tchetchelnitski, Viktoria; Mehmet, Huseyin
2013-02-01
Large-scale production of plasmid DNA to prepare therapeutic gene vectors or DNA-based vaccines requires a suitable bacterial host, which can stably maintain the plasmid DNA during industrial cultivation. Plasmid loss during bacterial cell divisions and structural changes in the plasmid DNA can dramatically reduce the yield of the desired recombinant plasmid DNA. While generating an HIV-based gene vector containing a bicistronic expression cassette 5'-Olig2cDNA-IRES-dsRed2-3', we encountered plasmid DNA instability, which occurred in homologous recombination deficient recA1 Escherichia coli strain Stbl2 specifically during large-scale bacterial cultivation. Unexpectedly, the new recombinant plasmid was structurally changed or completely lost in 0.5 L liquid cultures but not in the preceding 5 mL cultures. Neither the employment of an array of alternative recA1 E. coli plasmid hosts, nor the lowering of the culture incubation temperature prevented the instability. However, after the introduction of this instability-prone plasmid into the recA13E. coli strain Stbl3, the transformed bacteria grew without being overrun by plasmid-free cells, reduction in the plasmid DNA yield or structural changes in plasmid DNA. Thus, E. coli strain Stbl3 conferred structural and maintenance stability to the otherwise instability-prone lentivirus-based recombinant plasmid, suggesting that this strain can be used for the faithful maintenance of similar stability-compromised plasmids in large-scale bacterial cultivations. In contrast to Stbl2, which is derived wholly from the wild type isolate E. coli K12, E. coli Stbl3 is a hybrid strain of mixed E. coli K12 and E. coli B parentage. Therefore, we speculate that genetic determinants for the benevolent properties of E. coli Stbl3 for safe plasmid propagation originate from its E. coli B ancestor.
Complex Polynomial Vector Fields
DEFF Research Database (Denmark)
The two branches of dynamical systems, continuous and discrete, correspond to the study of differential equations (vector fields) and iteration of mappings respectively. In holomorphic dynamics, the systems studied are restricted to those described by holomorphic (complex analytic) functions...... vector fields. Since the class of complex polynomial vector fields in the plane is natural to consider, it is remarkable that its study has only begun very recently. There are numerous fundamental questions that are still open, both in the general classification of these vector fields, the decomposition...... of parameter spaces into structurally stable domains, and a description of the bifurcations. For this reason, the talk will focus on these questions for complex polynomial vector fields....
Complex Polynomial Vector Fields
DEFF Research Database (Denmark)
Dias, Kealey
The two branches of dynamical systems, continuous and discrete, correspond to the study of differential equations (vector fields) and iteration of mappings respectively. In holomorphic dynamics, the systems studied are restricted to those described by holomorphic (complex analytic) functions...... or meromorphic (allowing poles as singularities) functions. There already exists a well-developed theory for iterative holomorphic dynamical systems, and successful relations found between iteration theory and flows of vector fields have been one of the main motivations for the recent interest in holomorphic...... vector fields. Since the class of complex polynomial vector fields in the plane is natural to consider, it is remarkable that its study has only begun very recently. There are numerous fundamental questions that are still open, both in the general classification of these vector fields, the decomposition...
ON VECTOR NETWORK EQUILIBRIUM PROBLEMS
Institute of Scientific and Technical Information of China (English)
Guangya CHEN
2005-01-01
In this paper we define a concept of weak equilibrium for vector network equilibrium problems.We obtain sufficient conditions of weak equilibrium points and establish relation with vector network equilibrium problems and vector variational inequalities.
Kansas Data Access and Support Center — The Kansas Tagged Vector Contour (TVC) dataset consists of digitized contours from the 7.5 minute topographic quadrangle maps. Coverage for the state is incomplete....
Minnesota Department of Natural Resources — This vector dataset is a detailed (1-acre minimum), hierarchically organized vegetation cover map produced by computer classification of combined two-season pairs of...
Noncausal Bayesian Vector Autoregression
DEFF Research Database (Denmark)
Lanne, Markku; Luoto, Jani
We propose a Bayesian inferential procedure for the noncausal vector autoregressive (VAR) model that is capable of capturing nonlinearities and incorporating effects of missing variables. In particular, we devise a fast and reliable posterior simulator that yields the predictive distribution...
Vector Lattice Vortex Solitons
Institute of Scientific and Technical Information of China (English)
WANG Jian-Dong; YE Fang-Wei; DONG Liang-Wei; LI Yong-Ping
2005-01-01
@@ Two-dimensional vector vortex solitons in harmonic optical lattices are investigated. The stability properties of such solitons are closely connected to the lattice depth Vo. For small Vo, vector vortex solitons with the total zero-angular momentum are more stable than those with the total nonzero-angular momentum, while for large Vo, this case is inversed. If Vo is large enough, both the types of such solitons are stable.
Support vector machines applications
Guo, Guodong
2014-01-01
Support vector machines (SVM) have both a solid mathematical background and good performance in practical applications. This book focuses on the recent advances and applications of the SVM in different areas, such as image processing, medical practice, computer vision, pattern recognition, machine learning, applied statistics, business intelligence, and artificial intelligence. The aim of this book is to create a comprehensive source on support vector machine applications, especially some recent advances.
Navarro, Andres A
2013-01-01
We analyze a massive vector field with a non-canonical kinetic term in the action, minimally coupled to gravity, where the mass and kinetic function of the vector field vary as functions of time during inflation. The vector field is introduced following the same idea of a scalar curvaton, which must not affect the inflationary dynamics since its energy density during inflation is negligible compared to the total energy density in the Universe. Using this hypothesis, the vector curvaton will be solely responsible for generating the primordial curvature perturbation \\zeta. We have found that the spectra of the vector field perturbations are scale-invariant in superhorizon scales due to the suitable choice of the time dependence of the kinetic function and the effective mass during inflation. The preferred direction, generated by the vector field, makes the spectrum of \\zeta depend on the wavevector, i.e. there exists statistical anisotropy in \\zeta. This is discussed principally in the case where the mass of th...
Vector cross product in n-dimensional vector space
Tian, Xiu-Lao; Yang, Chao; Hu, Yang; Tian, Chao
2013-01-01
The definition of vector cross product (VCP) introduced by Eckmann only exists in thethree- and the seven- dimensional vector space. In this paper, according to the orthogonal completeness, magnitude of basis vector cross product and all kinds of combinations of basis vector $\\hat{e}_i$, the generalized definition of VCP in the odd n-dimensional vector space is given by introducing a cross term $X_{AB}$. In addition, the definition is validated by reducing the generalization definition to the...
Extended Mixed Vector Equilibrium Problems
Directory of Open Access Journals (Sweden)
Mijanur Rahaman
2014-01-01
Full Text Available We study extended mixed vector equilibrium problems, namely, extended weak mixed vector equilibrium problem and extended strong mixed vector equilibrium problem in Hausdorff topological vector spaces. Using generalized KKM-Fan theorem (Ben-El-Mechaiekh et al.; 2005, some existence results for both problems are proved in noncompact domain.
Bunyavirus-vector interactions.
Beaty, B J; Bishop, D H
1988-06-01
Recent advances in the genetics and molecular biology of bunyaviruses have been applied to understanding bunyavirus-vector interactions. Such approaches have revealed which virus gene and gene products are important in establishing infections in vectors and in transmission of viruses. However, much more information is required to understand the molecular mechanisms of persistent infections of vectors which are lifelong but apparently exert no untoward effect. In fact, it seems remarkable that LAC viral antigen can be detected in almost every cell in an ovarian follicle, yet no untoward effect on fecundity and no teratology is seen. Similarly the lifelong infection of the vector would seem to provide ample opportunity for bunyavirus evolution by genetic drift and, under the appropriate circumstances, by segment reassortment. The potential for bunyavirus evolution by segment reassortment in vectors certainly exists. For example the Group C viruses in a small forest in Brazil seem to constitute a gene pool, with the 6 viruses related alternately by HI/NT and CF reactions, which assay respectively M RNA and S RNA gene products (Casals and Whitman, 1960; Shope and Causey, 1962). Direct evidence for naturally occurring reassortant bunyaviruses has also been obtained. Oligonucleotide fingerprint analyses of field isolates of LAC virus and members of the Patois serogroup of bunyaviruses have demonstrated that reassortment does occur in nature (El Said et al., 1979; Klimas et al., 1981; Ushijima et al., 1981). Determination of the genotypic frequencies of viruses selected by the biological interactions of viruses and vectors after dual infection and segment reassortment is an important issue. Should a virus result that efficiently interacts with alternate vector species, the virus could be expressed in different circumstances with serious epidemiologic consequences. Dual infection of vectors with different viruses is not unlikely, because many bunyaviruses are sympatric in
Vector Fields on Product Manifolds
Kurz, Stefan
2011-01-01
This short report establishes some basic properties of smooth vector fields on product manifolds. The main results are: (i) On a product manifold there always exists a direct sum decomposition into horizontal and vertical vector fields. (ii) Horizontal and vertical vector fields are naturally isomorphic to smooth families of vector fields defined on the factors. Vector fields are regarded as derivations of the algebra of smooth functions.
Boosting Support Vector Machines
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Elkin Eduardo García Díaz
2006-11-01
Full Text Available En este artículo, se presenta un algoritmo de clasificación binaria basado en Support Vector Machines (Máquinas de Vectores de Soporte que combinado apropiadamente con técnicas de Boosting consigue un mejor desempeño en cuanto a tiempo de entrenamiento y conserva características similares de generalización con un modelo de igual complejidad pero de representación más compacta./ In this paper we present an algorithm of binary classification based on Support Vector Machines. It is combined with a modified Boosting algorithm. It run faster than the original SVM algorithm with a similar generalization error and equal complexity model but it has more compact representation.
Robustifying Vector Median Filter
Directory of Open Access Journals (Sweden)
Valentín Gregori
2011-08-01
Full Text Available This paper describes two methods for impulse noise reduction in colour images that outperform the vector median filter from the noise reduction capability point of view. Both methods work by determining first the vector median in a given filtering window. Then, the use of complimentary information from componentwise analysis allows to build robust outputs from more reliable components. The correlation among the colour channels is taken into account in the processing and, as a result, a more robust filter able to process colour images without introducing colour artifacts is obtained. Experimental results show that the images filtered with the proposed method contain less noisy pixels than those obtained through the vector median filter. Objective measures demonstrate the goodness of the achieved improvement.
Eisenman, Richard L
2005-01-01
This outstanding text and reference applies matrix ideas to vector methods, using physical ideas to illustrate and motivate mathematical concepts but employing a mathematical continuity of development rather than a physical approach. The author, who taught at the U.S. Air Force Academy, dispenses with the artificial barrier between vectors and matrices--and more generally, between pure and applied mathematics.Motivated examples introduce each idea, with interpretations of physical, algebraic, and geometric contexts, in addition to generalizations to theorems that reflect the essential structur
Free topological vector spaces
Gabriyelyan, Saak S.; Morris, Sidney A.
2016-01-01
We define and study the free topological vector space $\\mathbb{V}(X)$ over a Tychonoff space $X$. We prove that $\\mathbb{V}(X)$ is a $k_\\omega$-space if and only if $X$ is a $k_\\omega$-space. If $X$ is infinite, then $\\mathbb{V}(X)$ contains a closed vector subspace which is topologically isomorphic to $\\mathbb{V}(\\mathbb{N})$. It is proved that if $X$ is a $k$-space, then $\\mathbb{V}(X)$ is locally convex if and only if $X$ is discrete and countable. If $X$ is a metrizable space it is shown ...
Duality in vector optimization
Bot, Radu Ioan
2009-01-01
This book presents fundamentals and comprehensive results regarding duality for scalar, vector and set-valued optimization problems in a general setting. After a preliminary chapter dedicated to convex analysis and minimality notions of sets with respect to partial orderings induced by convex cones a chapter on scalar conjugate duality follows. Then investigations on vector duality based on scalar conjugacy are made. Weak, strong and converse duality statements are delivered and connections to classical results from the literature are emphasized. One chapter is exclusively consecrated to the s
Rejon-Barrera, Fernando
2015-01-01
We work out all of the details required for implementation of the conformal bootstrap program applied to the four-point function of two scalars and two vectors in an abstract conformal field theory in arbitrary dimension. This includes a review of which tensor structures make appearances, a construction of the projectors onto the required mixed symmetry representations, and a computation of the conformal blocks for all possible operators which can be exchanged. These blocks are presented as differential operators acting upon the previously known scalar conformal blocks. Finally, we set up the bootstrap equations which implement crossing symmetry. Special attention is given to the case of conserved vectors, where several simplifications occur.
Narici, Lawrence
2011-01-01
BackgroundTopology Valuation Theory Algebra Linear Functionals Hyperplanes Measure Theory Normed SpacesCommutative Topological GroupsElementary ConsiderationsSeparation and Compactness Bases at 0 for Group Topologies Subgroups and Products Quotients S-Topologies Metrizability CompletenessCompleteness Function Groups Total BoundednessCompactness and Total Boundedness Uniform Continuity Extension of Uniformly Continuous Maps CompletionTopological Vector SpacesAbsorbent and Balanced Sets Convexity-AlgebraicBasic PropertiesConvexity-Topological Generating Vector Topologies A Non-Locally Convex Spa
Treiman, Jay S
2014-01-01
Calculus with Vectors grew out of a strong need for a beginning calculus textbook for undergraduates who intend to pursue careers in STEM. fields. The approach introduces vector-valued functions from the start, emphasizing the connections between one-variable and multi-variable calculus. The text includes early vectors and early transcendentals and includes a rigorous but informal approach to vectors. Examples and focused applications are well presented along with an abundance of motivating exercises. All three-dimensional graphs have rotatable versions included as extra source materials and may be freely downloaded and manipulated with Maple Player; a free Maple Player App is available for the iPad on iTunes. The approaches taken to topics such as the derivation of the derivatives of sine and cosine, the approach to limits, and the use of "tables" of integration have been modified from the standards seen in other textbooks in order to maximize the ease with which students may comprehend the material. Additio...
Synthetic Space Vector Modulation
2013-06-01
Modulation RF Radio Frequency SVM Space Vector Modulation VCO Voltage Controlled Oscillator VSI Voltage Source Inverter xvi THIS PAGE...examining the literature, an NE566 voltage controlled oscillator ( VCO ) chip as seen in Figure 10 was used to design a circuit that produced the
Dean, Richard A.
1971-01-01
The author shows that the set of all sequences in which each term is the sum of the two previous terms forms a vector space of dimension two. He uses this result to obtain the formula for the Fibonacci sequence and applies the same technique to other linear recursive relations. (MM)
Centers for Disease Control (CDC) Podcasts
2011-04-18
This podcast discusses emerging vector-borne pathogens, their role as prominent contributors to emerging infectious diseases, how they're spread, and the ineffectiveness of mosquito control methods. Created: 4/18/2011 by National Center for Emerging Zoonotic and Infectious Diseases (NCEZID). Date Released: 4/27/2011.
DEFF Research Database (Denmark)
2000-01-01
Using a pulsed ultrasound field, the two-dimensional velocity vector can be determined with the invention. The method uses a transversally modulated ultrasound field for probing the moving medium under investigation. A modified autocorrelation approach is used in the velocity estimation. The new...
VECTOR BUNDLE, KILLING VECTOR FIELD AND PONTRYAGIN NUMBERS
Institute of Scientific and Technical Information of China (English)
周建伟
1991-01-01
Let E be a vector bundle over a compact Riemannian manifold M. We construct a natural metric on the bundle space E and discuss the relationship between the killing vector fields of E and M. Then we give a proof of the Bott-Baum-Cheeger Theorem for vector bundle E.
Vector grammars and PN machines
Institute of Scientific and Technical Information of China (English)
蒋昌俊
1996-01-01
The concept of vector grammars under the string semantic is introduced.The dass of vector grammars is given,which is similar to the dass of Chomsky grammars.The regular vector grammar is divided further.The strong and weak relation between the vector grammar and scalar grammar is discussed,so the spectrum system graph of scalar and vector grammars is made.The equivalent relation between the regular vector grammar and Petri nets (also called PN machine) is pointed.The hybrid PN machine is introduced,and its language is proved equivalent to the language of the context-free vector grammar.So the perfect relation structure between vector grammars and PN machines is formed.
On Generalized Vector Equilibrium Problems
Institute of Scientific and Technical Information of China (English)
An-hua Wan; Jun-yi Fu; Wei-hua Mao
2006-01-01
A new generalized vector equilibrium problem involving set-valued mappings and the proper quasi-concavity of set-valued mappings in topological vector spaces are introduced; its existence theorems and the convexity of the solution sets are established.
Indian Academy of Sciences (India)
Gy Wolf
2006-04-01
One consequence of the chiral restoration is the mixing of parity partners. We look for a possible signature of the mixing of vector and axial vector mesons in heavy-ion collisions. We suggest an experimental method for its observation. The dynamical evolution of the heavy-ion collision is described by a transport equation of QMD-type evolving nucleons, * and resonances, ’s and $\\sum$ baryons, and furthermore, ’s, ’s ’s ’s ’s and kaons with their isospin degrees of freedom. The input cross-sections and resonance parameters of the model are fitted to the available nucleon–nucleon and pion–nucleon cross-sections.
Davydov, Evgeny
2011-01-01
Vector fields can arise in the cosmological context in different ways, and we discuss both abelian and nonabelian sector. In the abelian sector vector fields of the geometrical origin (from dimensional reduction and Einstein-Eddington modification of gravity) can provide a very non-trivial dynamics, which can be expressed in terms of the effective dilaton-scalar gravity with the specific potential. In the non-abelian sector we investigate the Yang-Mills SU(2) theory which admits isotropic and homogeneous configuration. Provided the non-linear dependence of the lagrangian on the invariant F*F(dual), one can obtain the inflationary regime with the exponential growth of the scale factor. The effective amplitudes of the 'electric' and 'magnetic' components behave like slowly varying scalars at this regime, what allows the consideration of some realistic models with non-linear terms in the Yang-Mills lagrangian.
Rudakov, A N
1990-01-01
This volume is devoted to the use of helices as a method for studying exceptional vector bundles, an important and natural concept in algebraic geometry. The work arises out of a series of seminars organised in Moscow by A. N. Rudakov. The first article sets up the general machinery, and later ones explore its use in various contexts. As to be expected, the approach is concrete; the theory is considered for quadrics, ruled surfaces, K3 surfaces and P3(C).
Student Preconceptions about Vector Kinematics.
Aguirre, Jose M.
1988-01-01
Examines preconceptions regarding several implicit vector characteristics that 15- to 17-year-old students possess just before taking their first physics course. Shows seven vector characteristics and three tasks for interviewing students. Presents the most common student preconceptions regarding each of the implicit vector characteristics. (YP)
Decay Constants of Vector Mesons
Institute of Scientific and Technical Information of China (English)
LI Heng-Mei; WAN Shao-Long
2008-01-01
@@ The light vector mesons are studied within the framework of the Bethe-Salpeter equation with the vector-vectortype flat-bottom potential The Bethe-Salpeter wavefunctions and the decay constants of the vector mesons are obtained. All the obtained results, fρ, fφ, and fΚ* , are in agreement with the experimental values, respectively.
Interpolation of Vector Measures
Institute of Scientific and Technical Information of China (English)
Ricardo del CAMPO; Antonio FERN(A)NDEZ; Fernando MAYORAL; Francisco NARANJO; Enrique A. S(A)NCHEZ-P(E)REZ
2011-01-01
Let (Ω, ∑) be a measurable space and m0: ∑→ X0 and m1: ∑ -→ X1 be positive vector measures with values in the Banach K(o)the function spaces X0 and X1. If 0 < α < 1, we define a X10-αXα1 and we analyze the space of integrable functions with respect to measure [m0, m1]α in order to prove suitable extensions of the classical Stein-Weiss formulas that hold for the complex interpolation of Lp-spaces.Since each p-convex order continuous K(o)the function space with weak order unit can be represented as a space of p-integrable functions with respect to a vector measure, we provide in this way a technique to obtain representations of the corresponding complex interpolation spaces. As applications, we provide a Riesz-Thorin theorem for spaces of p-integrable functions with respect to vector measures and a formula for representing the interpolation of the injective tensor product of such spaces.
Relativistic Rotating Vector Model
Lyutikov, Maxim
2016-01-01
The direction of polarization produced by a moving source rotates with the respect to the rest frame. We show that this effect, induced by pulsar rotation, leads to an important correction to polarization swings within the framework of rotating vector model (RVM); this effect has been missed by previous works. We construct relativistic RVM taking into account finite heights of the emission region that lead to aberration, time-of-travel effects and relativistic rotation of polarization. Polarizations swings at different frequencies can be used, within the assumption of the radius-to-frequency mapping, to infer emission radii and geometry of pulsars.
1992-01-01
El texto Números, Vectores y Funciones que han elaborado los profesores Asociados Omar Evelio Ospina y Bernardo Acevedo, responden a esta necesidad con sobresalientes cualidades pedagógicas, entre las cuales se destacan el desarrollo detallado de los temas y la proliferación de ejercicios resueltos, lo cual genera un diálogo directo con el lector que puede así aprovechar totalmente su lectura. El material presentado es el fruto de un cuidadoso análisis de los autores, sobre las experiencias d...
Vector potential photoelectron microscopy.
Browning, R
2011-10-01
A new class of electron microscope has been developed for the chemical microanalysis of a wide range of real world samples using photoelectron spectroscopy. Highly structured, three-dimensional samples, such as fiber mats and fracture surfaces can be imaged, as well as insulators and magnetic materials. The new microscope uses the vector potential field from a solenoid magnet as a spatial reference for imaging. A prototype instrument has demonstrated imaging of uncoated silk, magnetic steel wool, and micron-sized single strand tungsten wires.
Extended vector-tensor theories
Kimura, Rampei; Naruko, Atsushi; Yoshida, Daisuke
2017-01-01
Recently, several extensions of massive vector theory in curved space-time have been proposed in many literatures. In this paper, we consider the most general vector-tensor theories that contain up to two derivatives with respect to metric and vector field. By imposing a degeneracy condition of the Lagrangian in the context of ADM decomposition of space-time to eliminate an unwanted mode, we construct a new class of massive vector theories where five degrees of freedom can propagate, corresponding to three for massive vector modes and two for massless tensor modes. We find that the generalized Proca and the beyond generalized Proca theories up to the quartic Lagrangian, which should be included in this formulation, are degenerate theories even in curved space-time. Finally, introducing new metric and vector field transformations, we investigate the properties of thus obtained theories under such transformations.
Semitopological Vector Spaces and Hyperseminorms
Directory of Open Access Journals (Sweden)
Mark Burgin
2013-11-01
Full Text Available In this paper, we introduce and study semitopological vector spaces. The goal is to provide an efficient base for developing the theory of extrafunction spaces in an abstract setting of algebraic systems and topological spaces. Semitopological vector spaces are more general than conventional topological vector spaces, which proved to be very useful for solving many problems in functional analysis. To study semitopological vector spaces, hypermetrics and hyperpseudometrics are introduced and it is demonstrated that hyperseminorms, studied in previous works of the author, induce hyperpseudometrics, while hypernorms induce hypermetrics. Sufficient and necessary conditions for a hyperpseudometric (hypermetric to be induced by a hyperseminorm (hypernorm are found. We also show that semitopological vector spaces are closely related to systems of hyperseminorms. Then defining boundedness and continuity relative to associated systems of hyperseminorms, we study relations between relative boundedness and relative continuity for mappings of vector spaces with systems of hyperseminorms and systems of hypernorms.
Safety considerations in vector development.
Kappes, J C; Wu, X
2001-11-01
The inadvertent production of replication competent retrovirus (RCR) constitutes the principal safety concern for the use of lentiviral vectors in human clinical protocols. Because of limitations in animal models to evaluate lentiviral vectors for their potential to recombine and induce disease, the vector design itself should ensure against the emergence of RCR in vivo. Issues related to RCR generation and one approach to dealing with this problem are discussed in this chapter. To assess the risk of generating RCR, a highly sensitive biological assay was developed to specifically detect vector recombination in transduced cells. Analysis of lentiviral vector stocks has shown that recombination occurs during reverse transcription in primary target cells. Rejoining of viral protein-coding sequences of the packaging construct and cis-acting sequences of the vector was demonstrated to generate env-minus recombinants (LTR-gag-pol-LTR). Mobilization of recombinant lentiviral genomes was also demonstrated but was dependent on pseudotyping of the vector core with an exogenous envelope protein. 5' sequence analysis has demonstrated that recombinants consist of U3, R, U5, and the psi packaging signal joined with an open gag coding region. Analysis of the 3' end has mapped the point of vector recombination to the poly(A) tract of the packaging construct's mRNA. The state-of-the-art third generation packaging construct and SIN vector also have been shown to generate env-minus proviral recombinants capable of mobilizing retroviral DNA when pseudotyped with an exogenous envelope protein. A new class of HIV-based vector (trans-vector) was recently developed that splits the gag-pol component of the packaging construct into two parts: one that expresses Gag/Gag-Pro and another that expresses Pol (RT and IN) fused with Vpr. Unlike other lentiviral vectors, the trans-vector has not been shown to form recombinants capable of DNA mobilization. These results indicate the trans-vector
VLSI Processor For Vector Quantization
Tawel, Raoul
1995-01-01
Pixel intensities in each kernel compared simultaneously with all code vectors. Prototype high-performance, low-power, very-large-scale integrated (VLSI) circuit designed to perform compression of image data by vector-quantization method. Contains relatively simple analog computational cells operating on direct or buffered outputs of photodetectors grouped into blocks in imaging array, yielding vector-quantization code word for each such block in sequence. Scheme exploits parallel-processing nature of vector-quantization architecture, with consequent increase in speed.
D'Ambrosio, Vincenzo; Carvacho, Gonzalo; Graffitti, Francesco; Vitelli, Chiara; Piccirillo, Bruno; Marrucci, Lorenzo; Sciarrino, Fabio
2016-09-01
Light beams having a vectorial field structure, or polarization, that varies over the transverse profile and a central optical singularity are called vector vortex (VV) beams and may exhibit specific properties such as focusing into "light needles" or rotation invariance. VV beams have already found applications in areas ranging from microscopy to metrology, optical trapping, nano-optics, and quantum communication. Individual photons in such beams exhibit a form of single-particle quantum entanglement between different degrees of freedom. On the other hand, the quantum states of two photons can be also entangled with each other. Here, we combine these two concepts and demonstrate the generation of quantum entanglement between two photons that are both in VV states: a form of entanglement between two complex vectorial fields. This result may lead to quantum-enhanced applications of VV beams as well as to quantum information protocols fully exploiting the vectorial features of light.
Buchin, Kevin; Moser, Robin A; Pálvölgyi, Dömötör
2009-01-01
For an integer d>=1, let tau(d) be the smallest integer with the following property: If v1,v2,...,vt is a sequence of t>=2 vectors in [-1,1]^d with v1+v2+...+vt in [-1,1]^d, then there is a subset S of {1,2,...,t} of indices, 2= d^{d/2-o(d)}. These results contribute to understanding the master equality polyhedron with multiple rows defined by Dash et al., which is a "universal" polyhedron encoding valid cutting planes for integer programs (this line of research was started by Gomory in the late 1960s). In particular, the upper bound on tau(d) implies a pseudo-polynomial running time for an algorithm of Dash et al. for integer programming with a fixed number of constraints. The algorithm consists in solving a linear program, and it provides an alternative to a 1981 dynamic programming algorithm of Papadimitriou.
Kolpakov, Stanislav A; Loika, Yuri; Tarasov, Nikita; Kalashnikov, Vladimir; Agrawal, Govind P
2015-01-01
A mode locked fibre laser as a source of ultra-stable pulse train has revolutionised a wide range of fundamental and applied research areas by offering high peak powers, high repetition rates, femtosecond range pulse widths and a narrow linewidth. However, further progress in linewidth narrowing seems to be limited by the complexity of the carrier-envelope phase control. Here for the first time we demonstrate experimentally and theoretically a new mechanism of resonance vector self-mode locking where tuning in-cavity birefringence leads to excitation of the longitudinal modes sidebands accompanied by the resonance phase locking of sidebands with the adjacent longitudinal modes. An additional resonance with acoustic phonons provides the repetition rate tunability and linewidth narrowing down to Hz range that drastically reduces the complexity of the carrier-envelope phase control and so will open the way to advance lasers in the context of applications in metrology, spectroscopy, microwave photonics, astronomy...
Vector-Tensor and Vector-Vector Decay Amplitude Analysis of B0->phi K*0
Aubert, B; Abrams, G S; Adye, T; Ahmed, S; Alam, M S; Albert, J; Aleksan, R; Allen, M T; Allison, J; Altenburg, D D; Andreotti, M; Angelini, C; Anulli, F; Arnaud, N; Asgeirsson, D J; Aston, D; Azzolini, V; Baak, M A; Back, J J; Baldini-Ferroli, R; Band, H R; Banerjee, Sw; Bard, D J; Barlow, N R; Barlow, R J; Barrett, M; Bartoldus, R; Batignani, G; Battaglia, M; Bauer, J M; Bechtle, P; Beck, T W; Behera, P K; Bellini, F; Benayoun, M; Benelli, G; Berger, N; Bernard, D; Berryhill, J W; Best, D S; Bettarini, S; Bettoni, D; Bevan, A J; Bhimji, W; Bhuyan, B; Bianchi, F; Biasini, M; Biesiada, J; Blanc, F; Blaylock, G; Blinov, V E; Bloom, P C; Blount, N L; Bomben, M; Bondioli, M; Bonneaud, G R; Bosisio, L; Boutigny, D; Bowerman, D A; Boyd, J T; Bozzi, C; Brandenburg, G; Brandt, T; Brau, J E; Briand, H; Brown, C M; Brown, D N; Bruinsma, M; Brunet, S; Bucci, F; Buchanan, C; Bugg, W; Bukin, A D; Bula, R; Burchat, P R; Burke, J P; Button-Shafer, J; Buzzo, A; Bóna, M; Cahn, R N; Calabrese, R; Calcaterra, A; Calderini, G; Campagnari, C; Carpinelli, M; Cartaro, C; Cavallo, N; Cavoto, G; Cenci, R; Chai, X; Chaisanguanthum, K S; Chao, M; Charles, E; Charles, M J; Chauveau, J; Chavez, C A; Chen, A; Chen, C; Chen, E; Chen, J C; Chen, S; Chen, X; Chen, X R; Cheng, B; Cheng, C H; Chia, Y M; Cibinetto, G; Clark, P J; Clarke, C K; Claus, R; Cochran, J; Coleman, J P; Contri, R; Convery, M R; Corwin, L A; Cossutti, F; Cottingham, W N; Couderc, F; Covarelli, R; Cowan, G; Cowan, R; Crawley, H B; Cremaldi, L; Cunha, A; Curry, S; Côté, D; D'Orazio, A; Dahmes, B; Dallapiccola, C; Danielson, N; Dasu, S; Datta, M; Dauncey, P D; David, P; Davier, M; Davis, C L; De Nardo, Gallieno; De Sangro, R; Del Amo-Sánchez, P; Del Buono, L; Del Re, D; Della Ricca, G; Denig, A G; Di Lodovico, F; Di Marco, E; Dingfelder, J C; Dittongo, S; Dong, L; Dorfan, J; Druzhinin, V P; Dubitzky, R S; Dubois-Felsmann, G P; Dujmic, D; Dunwoodie, W M; Dvoretskii, A; Ebert, M; Eckhart, E A; Eckmann, R; Edgar, C L; Edwards, A J; Egede, U; Eigen, G; Eisner, A M; Elmer, P; Emery, S; Ernst, J A; Eschenburg, V; Eschrich, I; Eyges, V; Fabozzi, F; Faccini, R; Fang, F; Feltresi, E; Ferrarotto, F; Ferroni, F; Field, R C; Finocchiaro, G; Flacco, C J; Flack, R L; Flächer, H U; Flood, K T; Ford, K E; Ford, W T; Forster, I J; Forti, F; Fortin, D; Foulkes, S D; Franek, B; Frey, R; Fritsch, M; Fry, J R; Fulsom, B G; Gabathuler, E; Gaidot, A; Gallo, F; Gamba, D; Gamet, R; Gan, K K; Ganzhur, S F; Gao, Y; Gary, J W; Gaspero, M; Gatto, C; Gaz, A; George, K A; Gill, M S; Giorgi, M A; Gladney, L; Glanzman, T; Godang, R; Golubev, V B; Gowdy, S J; Gradl, W; Graham, M T; Graugès-Pous, E; Grenier, P; Gritsan, A V; Grosdidier, G; Groysman, Y; Guo, Z J; Hadavand, H K; Haire, M; Halyo, V; Hamano, K; Hamel de Monchenault, G; Hamon, O; Harrison, P F; Harrison, T J; Hart, A J; Hartfiel, B L; Hast, C; Hauke, A; Hawkes, C M; Hearty, C; Held, T; Hertzbach, S S; Heusch, C A; Hill, E J; Hirschauer, J F; Hitlin, D G; Hollar, J J; Hong, T M; Honscheid, K; Hopkins, D A; Hrynóva, T; Hufnagel, D; Hulsbergen, W D; Hutchcroft, D E; Höcker, A; Igonkina, O; Innes, W R; Izen, J M; Jackson, P D; Jackson, P S; Jacobsen, R G; Jain, V; Jasper, H; Jawahery, A; Jessop, C P; Judd, D; Kadyk, J A; Kagan, H; Karyotakis, Yu; Kass, R; Kelsey, M H; Kerth, L T; Khan, A; Kim, H; Kim, P; Kirkby, D; Klose, V; Knecht, N S; Koch, H; Kolb, J A; Kolomensky, Yu G; Kovalskyi, D; Kowalewski, R V; Kozanecki, Witold; Kreisel, A; Krishnamurthy, M; Kroeger, R; Kroseberg, J; Kukartsev, G; Kutter, P E; Kyberd, P; La Vaissière, C de; Lacker, H M; Lae, C K; Lafferty, G D; Lanceri, L; Lange, D J; Lankford, A J; Latham, T E; Latour, E; Lau, Y P; Lazzaro, A; Le Diberder, F R; Lee, C L; Lees, J P; Legendre, M; Leith, D W G S; Lepeltier, V; Leruste, P; Lewandowski, B; Li Gioi, L; Li, S; Li, X; Lista, L; Liu, H; Lo Vetere, M; LoSecco, J M; Lockman, W S; Lombardo, V; Long, O; Lopes-Pegna, D; Lopez-March, N; Lou, X C; Lu, M; Luitz, S; Lund, P; Luppi, E; Lusiani, A; Lutz, A M; Lynch, G; Lynch, H L; Lü, C; Lüth, V; MacFarlane, D B; Macri, M M; Mader, W F; Majewski, S A; Malcles, J; Mallik, U; Mancinelli, G; Mandelkern, M A; Marchiori, G; Margoni, M; Marks, J; Marsiske, H; Martínez-Vidal, F; Mattison, T S; Mazur, M A; Mazzoni, M A; McKenna, J A; McMahon, T R; Mclachlin, S E; Meadows, B T; Mellado, B; Menges, W; Merkel, J; Messner, R; Meyer, N T; Meyer, W T; Mihályi, A; Mir, L M; Mishra, K; Mohanty, G B; Monge, M R; Monorchio, D; Moore, T B; Morandin, M; Morganti, M; Morganti, S; Morii, M; Muheim, F; Müller, D R; Nagel, M; Naisbit, M T; Narsky, I; Nash, J A; Nauenberg, U; Neal, H; Negrini, M; Neri, N; Nesom, G; Nicholson, H; Nikolich, M B; Nogowski, R; Nugent, I M; O'Grady, C P; Ocariz, J; Ofte, I; Olaiya, E O; Olivas, A; Olsen, J; Onuchin, A P; Orimoto, T J; Oyanguren, A; Ozcan, V E; Paar, H P; Pacetti, S; Palano, A; Palombo, F; Pan, B; Pan, Y; Panduro, W; Paoloni, E; Paolucci, P; Pappagallo, M; Park, W; Passaggio, S; Patel, P M; Patrignani, C; Patteri, P; Payne, D J; Pelizaeus, M; Perazzo, A; Perl, M; Peruzzi, I M; Peters, K; Petersen, B A; Petrella, A; Petzold, A; Piatenko, T; Piccolo, D; Piccolo, M; Piemontese, L; Pierini, M; Piredda, G; Playfer, S; Poireau, V; Polci, F; Pompili, A; Porter, F C; Posocco, M; Potter, C T; Prell, S; Prencipe, E; Prepost, R; Pripstein, M; Pruvot, S; Pulliam, T; Purohit, M V; Qi, N D; Rahatlou, S; Rahimi, A M; Rahmat, R; Rama, M; Ratcliff, B N; Raven, G; Regensburger, J J; Ricciardi, S; Richman, J D; Ritchie, J L; Rizzo, G; Roberts, D A; Robertson, A I; Robertson, S H; Robutti, E; Rodier, S; Roe, N A; Ronan, M T; Roney, J M; Rong, G; Roodman, A; Roos, L; Rosenberg, E I; Rotondo, M; Roudeau, P; Rubin, A E; Ruddick, W O; Röthel, W; Sacco, R; Saeed, M A; Safai-Tehrani, F; Saleem, M; Salnikov, A A; Salvatore, F; Sanders, D A; Santroni, A; Saremi, S; Satpathy, A; Schalk, T; Schenk, S; Schilling, C J; Schindler, R H; Schofield, K C; Schott, G; Schröder, T; Schröder, H; Schubert, J; Schubert, K R; Schumm, B A; Schune, M H; Schwiening, J; Schwierz, R; Schwitters, R F; Sciacca, C; Sciolla, G; Seiden, A; Sekula, S J; Serednyakov, S I; Serrano, J; Sharma, V; Shen, B C; Sherwood, D J; Simard, M; Simi, G; Simonetto, F; Sinev, N B; Skovpen, Yu I; Smith, A J S; Smith, J G; Snoek, H L; Snyder, A; Sobie, R J; Soffer, A; Sokoloff, M D; Solodov, E P; Spaan, B; Spanier, S M; Spitznagel, M; Spradlin, P; Steinke, M; Stelzer, J; Stocchi, A; Stoker, D P; Stroili, R; Strom, D; Strube, J; Stugu, B; Stängle, H; Su, D; Sullivan, M K; Summers, D J; Sundermann, J E; Suzuki, K; Swain, S K; Taras, P; Taylor, F; Telnov, A V; Teodorescu, L; Ter-Antonian, R; Therin, G; Thiebaux, C; Thompson, J M; Tisserand, V; Todyshev, Y K; Toki, W H; Torrence, E; Tosi, S; Touramanis, C; Ulmer, K A; Uwer, U; Van Bakel, N; Vasseur, G; Vavra, J; Vazquez, A; Verderi, M; Viaud, F B; Vitale, L; Voci, C; Voena, C; Volk, A; Wagner, A P; Wagner, S R; Wagoner, D E; Waldi, R; Walker, D; Walsh, J J; Wang, K; Wang, P; Wang, W F; Wappler, F R; Watson, A T; Weaver, M; Weinstein, A J R; Wenzel, W A; Wilden, L; Williams, D C; Williams, J C; Wilson, F F; Wilson, J R; Wilson, M G; Wilson, R J; Winklmeier, F; Wisniewski, W J; Wittgen, M; Wong, Q K; Wormser, G; Wren, A C; Wright, D H; Wright, D M; Wu, J; Wu, S L; Wulsin, H W; Xie, Y; Yamamoto, R K; Yarritu, A K; Ye, S; Yi, J I; Yi, K; Young, C C; Yu, Z; Yéche, C; Zain, S B; Zallo, A; Zeng, Q; Zghiche, A; Zhang, J; Zhang, L; Zhao, H W; Zhu, Y S; Ziegler, V; Zito, M; Çuhadar-Dönszelmann, T; al, et
2007-01-01
We perform an amplitude analysis of the decays B0->phi K^*_2(1430)0, phi K^*(892)0, and phi(K pi)^0_S-wave with a sample of about 384 million BBbar pairs recorded with the BABAR detector. The fractions of longitudinal polarization f_L of the vector-tensor and vector-vector decay modes are measured to be 0.853 +0.061-0.069 +-0.036 and 0.506 +-0.040 +-0.015, respectively. Overall, twelve parameters are measured for the vector-vector decay and seven parameters for the vector-tensor decay, including the branching fractions and parameters sensitive to CP-violation.
Testing identifiablility of cointegrating vectors
H.P. Boswijk
1996-01-01
This article analyzes the identification and normalization of cointegrating vectors. Normalizing a cointegrating relation with respect to one of the relevant variables is with loss of generality; and restrictions that are supposed to identify a vector may fail to do so for particular parameter value
The Neural Support Vector Machine
Wiering, Marco; van der Ree, Michiel; Embrechts, Mark; Stollenga, Marijn; Meijster, Arnold; Nolte, A; Schomaker, Lambertus
2013-01-01
This paper describes a new machine learning algorithm for regression and dimensionality reduction tasks. The Neural Support Vector Machine (NSVM) is a hybrid learning algorithm consisting of neural networks and support vector machines (SVMs). The output of the NSVM is given by SVMs that take a centr
GPU Accelerated Vector Median Filter
Aras, Rifat; Shen, Yuzhong
2011-01-01
Noise reduction is an important step for most image processing tasks. For three channel color images, a widely used technique is vector median filter in which color values of pixels are treated as 3-component vectors. Vector median filters are computationally expensive; for a window size of n x n, each of the n(sup 2) vectors has to be compared with other n(sup 2) - 1 vectors in distances. General purpose computation on graphics processing units (GPUs) is the paradigm of utilizing high-performance many-core GPU architectures for computation tasks that are normally handled by CPUs. In this work. NVIDIA's Compute Unified Device Architecture (CUDA) paradigm is used to accelerate vector median filtering. which has to the best of our knowledge never been done before. The performance of GPU accelerated vector median filter is compared to that of the CPU and MPI-based versions for different image and window sizes, Initial findings of the study showed 100x improvement of performance of vector median filter implementation on GPUs over CPU implementations and further speed-up is expected after more extensive optimizations of the GPU algorithm .
Vectors on the Basketball Court
Bergman, Daniel
2010-01-01
An Idea Bank published in the April/May 2009 issue of "The Science Teacher" describes an experiential physics lesson on vectors and vector addition (Brown 2009). Like its football predecessor, the basketball-based investigation presented in this Idea Bank addresses National Science Education Standards Content B, Physical Science, 9-12 (NRC 1996)…
Simplified Representation of Vector Fields
Telea, Alexandru; Wijk, Jarke J. van
1999-01-01
Vector field visualization remains a difficult task. Although many local and global visualization methods for vector fields such as flow data exist, they usually require extensive user experience on setting the visualization parameters in order to produce images communicating the desired insight. We
Estimation of Motion Vector Fields
DEFF Research Database (Denmark)
Larsen, Rasmus
1993-01-01
This paper presents an approach to the estimation of 2-D motion vector fields from time varying image sequences. We use a piecewise smooth model based on coupled vector/binary Markov random fields. We find the maximum a posteriori solution by simulated annealing. The algorithm generate sample...
Emerging vector borne diseases – incidence through vectors
Directory of Open Access Journals (Sweden)
Sara eSavic
2014-12-01
Full Text Available Vector borne diseases use to be a major public health concern only in tropical and subtropical areas, but today they are an emerging threat for the continental and developed countries also. Nowdays, in intercontinetal countries, there is a struggle with emerging diseases which have found their way to appear through vectors. Vector borne zoonotic diseases occur when vectors, animal hosts, climate conditions, pathogens and susceptible human population exist at the same time, at the same place. Global climate change is predicted to lead to an increase in vector borne infectious diseases and disease outbreaks. It could affect the range and popultion of pathogens, host and vectors, transmission season, etc. Reliable surveilance for diseases that are most likely to emerge is required. Canine vector borne diseases represent a complex group of diseases including anaplasmosis, babesiosis, bartonellosis, borreliosis, dirofilariosis, erlichiosis, leishmaniosis. Some of these diseases cause serious clinical symptoms in dogs and some of them have a zoonotic potential with an effect to public health. It is expected from veterinarians in coordination with medical doctors to play a fudamental role at primeraly prevention and then treatment of vector borne diseases in dogs. The One Health concept has to be integrated into the struggle against emerging diseases.During a four year period, from 2009-2013, a total number of 551 dog samples were analysed for vector borne diseases (borreliosis, babesiosis, erlichiosis, anaplasmosis, dirofilariosis and leishmaniasis in routine laboratory work. The analysis were done by serological tests – ELISA for borreliosis, dirofilariosis and leishmaniasis, modified Knott test for dirofilariosis and blood smear for babesiosis, erlichiosis and anaplasmosis. This number of samples represented 75% of total number of samples that were sent for analysis for different diseases in dogs. Annually, on avarege more then half of the samples
Chikungunya Virus–Vector Interactions
Directory of Open Access Journals (Sweden)
Lark L. Coffey
2014-11-01
Full Text Available Chikungunya virus (CHIKV is a mosquito-borne alphavirus that causes chikungunya fever, a severe, debilitating disease that often produces chronic arthralgia. Since 2004, CHIKV has emerged in Africa, Indian Ocean islands, Asia, Europe, and the Americas, causing millions of human infections. Central to understanding CHIKV emergence is knowledge of the natural ecology of transmission and vector infection dynamics. This review presents current understanding of CHIKV infection dynamics in mosquito vectors and its relationship to human disease emergence. The following topics are reviewed: CHIKV infection and vector life history traits including transmission cycles, genetic origins, distribution, emergence and spread, dispersal, vector competence, vector immunity and microbial interactions, and co-infection by CHIKV and other arboviruses. The genetics of vector susceptibility and host range changes, population heterogeneity and selection for the fittest viral genomes, dual host cycling and its impact on CHIKV adaptation, viral bottlenecks and intrahost diversity, and adaptive constraints on CHIKV evolution are also discussed. The potential for CHIKV re-emergence and expansion into new areas and prospects for prevention via vector control are also briefly reviewed.
Stable piecewise polynomial vector fields
Directory of Open Access Journals (Sweden)
Claudio Pessoa
2012-09-01
Full Text Available Let $N={y>0}$ and $S={y<0}$ be the semi-planes of $mathbb{R}^2$ having as common boundary the line $D={y=0}$. Let $X$ and $Y$ be polynomial vector fields defined in $N$ and $S$, respectively, leading to a discontinuous piecewise polynomial vector field $Z=(X,Y$. This work pursues the stability and the transition analysis of solutions of $Z$ between $N$ and $S$, started by Filippov (1988 and Kozlova (1984 and reformulated by Sotomayor-Teixeira (1995 in terms of the regularization method. This method consists in analyzing a one parameter family of continuous vector fields $Z_{epsilon}$, defined by averaging $X$ and $Y$. This family approaches $Z$ when the parameter goes to zero. The results of Sotomayor-Teixeira and Sotomayor-Machado (2002 providing conditions on $(X,Y$ for the regularized vector fields to be structurally stable on planar compact connected regions are extended to discontinuous piecewise polynomial vector fields on $mathbb{R}^2$. Pertinent genericity results for vector fields satisfying the above stability conditions are also extended to the present case. A procedure for the study of discontinuous piecewise vector fields at infinity through a compactification is proposed here.
Vector fields on nonorientable surfaces
Directory of Open Access Journals (Sweden)
Dorin Ghisa
2003-01-01
Full Text Available A one-to-one correspondence is established between the germs of functions and tangent vectors on a NOS X and the bi-germs of functions, respectively, elementary fields of tangent vectors (EFTV on the orientable double cover of X. Some representation theorems for the algebra of germs of functions, the tangent space at an arbitrary point of X, and the space of vector fields on X are proved by using a symmetrisation process. An example related to the normal derivative on the border of the MÃƒÂ¶bius strip supports the nontriviality of the concepts introduced in this paper.
Vector boson scattering at CLIC
Energy Technology Data Exchange (ETDEWEB)
Kilian, Wolfgang; Fleper, Christian [Department Physik, Universitaet Siegen, 57068 Siegen (Germany); Reuter, Juergen [DESY Theory Group, 22603 Hamburg (Germany); Sekulla, Marco [Institut fuer Theoretische Physik, Karlsruher Institut fuer Technologie, 76131 Karlsruhe (Germany)
2016-07-01
Linear colliders operating in a range of multiple TeV are able to investigate the details of vector boson scattering and electroweak symmetry breaking. We calculate cross sections with the Monte Carlo generator WHIZARD for vector boson scattering processes at the future linear e{sup +} e{sup -} collider CLIC. By finding suitable cuts, the vector boson scattering signal processes are isolated from the background. Finally, we are able to determine exclusion sensitivities on the non-Standard Model parameters of the relevant dimension eight operators.
Vector control of induction machines
Robyns, Benoit
2012-01-01
After a brief introduction to the main law of physics and fundamental concepts inherent in electromechanical conversion, ""Vector Control of Induction Machines"" introduces the standard mathematical models for induction machines - whichever rotor technology is used - as well as several squirrel-cage induction machine vector-control strategies. The use of causal ordering graphs allows systematization of the design stage, as well as standardization of the structure of control devices. ""Vector Control of Induction Machines"" suggests a unique approach aimed at reducing parameter sensitivity for
DEFF Research Database (Denmark)
Davis, Christopher James; Kedlaya, Kiran
2014-01-01
We study the kernel and cokernel of the Frobenius map on the p-typical Witt vectors of a commutative ring, not necessarily of characteristic p. We give many equivalent conditions to surjectivity of the Frobenius map on both finite and infinite length Witt vectors. In particular, surjectivity...... on finite Witt vectors turns out to be stable under certain integral extensions; this provides a clean formulation of a strong generalization of Faltings’s almost purity theorem from p-adic Hodge theory, incorporating recent improvements by Kedlaya–Liu and by Scholze....
All optical vector magnetometer Project
National Aeronautics and Space Administration — This Phase I research project will investigate a novel method of operating an atomic magnetometer to simultaneously measure total magnetic fields and vector magnetic...
Introduction to matrices and vectors
Schwartz, Jacob T
2001-01-01
In this concise undergraduate text, the first three chapters present the basics of matrices - in later chapters the author shows how to use vectors and matrices to solve systems of linear equations. 1961 edition.
GRE Enzymes for Vector Analysis
U.S. Environmental Protection Agency — Microbial enzyme data that were collected during the 2004-2006 EMAP-GRE program. These data were then used by Moorhead et al (2016) in their ecoenzyme vector...
Acoustic vector sensor signal processing
Institute of Scientific and Technical Information of China (English)
SUN Guiqing; LI Qihu; ZHANG Bin
2006-01-01
Acoustic vector sensor simultaneously, colocately and directly measures orthogonal components of particle velocity as well as pressure at single point in acoustic field so that is possible to improve performance of traditional underwater acoustic measurement devices or detection systems and extends new ideas for solving practical underwater acoustic engineering problems. Although acoustic vector sensor history of appearing in underwater acoustic area is no long, but with huge and potential military demands, acoustic vector sensor has strong development trend in last decade, it is evolving into a one of important underwater acoustic technology. Under this background, we try to review recent progress in study on acoustic vector sensor signal processing, such as signal detection, DOA estimation, beamforming, and so on.
Transcriptional Silencing of Retroviral Vectors
DEFF Research Database (Denmark)
Lund, Anders Henrik; Duch, M.; Pedersen, F.S.
1996-01-01
. Extinction of long-term vector expression has been observed after implantation of transduced hematopoietic cells as well as fibroblasts, myoblasts and hepatocytes. Here we review the influence of vector structure, integration site and cell type on transcriptional silencing. While down-regulation of proviral...... transcription is known from a number of cellular and animal models, major insight has been gained from studies in the germ line and embryonal cells of the mouse. Key elements for the transfer and expression of retroviral vectors, such as the viral transcriptional enhancer and the binding site for the t......RNA primer for reverse transcription may have a major influence on transcriptional silencing. Alterations of these elements of the vector backbone as well as the use of internal promoter elements from housekeeping genes may contribute to reduce transcriptional silencing. The use of cell culture and animal...
Unsupervised learning of binary vectors
Copelli Lopes da Silva, Mauro
In this thesis, unsupervised learning of binary vectors from data is studied using methods from Statistical Mechanics of disordered systems. In the model, data vectors are distributed according to a single symmetry-breaking direction. The aim of unsupervised learning is to provide a good approximation to this direction. The difference with respect to previous studies is the knowledge that this preferential direction has binary components. It is shown that sampling from the posterior distribution (Gibbs learning) leads, for general smooth distributions, to an exponentially fast approach to perfect learning in the asymptotic limit of large number of examples. If the distribution is non-smooth, then first order phase transitions to perfect learning are expected. In the limit of poor performance, a second order phase transition ("retarded learning") is predicted to occur if the data distribution is not biased. Using concepts from Bayesian inference, the center of mass of the Gibbs ensemble is shown to have maximal average (Bayes-optimal) performance. This upper bound for continuous vectors is extended to a discrete space, resulting in the clipped center of mass of the Gibbs ensemble having maximal average performance among the binary vectors. To calculate the performance of this best binary vector, the geometric properties of the center of mass of binary vectors are studied. The surprising result is found that the center of mass of infinite binary vectors which obey some simple constraints, is again a binary vector. When disorder is taken into account in the calculation, however, a vector with continuous components is obtained. The performance of the best binary vector is calculated and shown to always lie above that of Gibbs learning and below the Bayes-optimal performance. Making use of a variational approach under the replica symmetric ansatz, an optimal potential is constructed in the limits of zero temperature and mutual overlap 1. Minimization of this potential
Disease Vector Ecology Profile: Colombia
1998-12-01
Cordillera Oriental. Studies in Norte de Santander Department in 1985 indicate 15.6% of the houses were infested with the vector, 30% of the...population studied had positive serologies, and 9% displayed abnormal heart function. Trypanosoma cruzi is found in animals and extradomiciliary vectors...drainage toward Lopez, the river slows and Simulium exiguum are less abundant than they are near San Antonio. From 1990-1995, Ivermectin (antihelminthic
Hagedorn, Claudia; Baiker, Armin; Postberg, Jan; Ehrhardt, Anja; Lipps, Hans J
2012-06-01
Nonviral episomal vectors represent attractive alternatives to currently used virus-based expression systems. In the late 1990s, it was shown that a plasmid containing an expression cassette linked to a scaffold/matrix attached region (S/MAR) replicates as a low copy number episome in all cell lines tested, as well as primary cells, and can be used for the genetic modification of higher animals. Once established in the cell, the S/MAR vector replicates early during S-phase and, in the absence of selection, is stably retained in the cells for an unlimited period of time. This vector can therefore be regarded as a minimal model system for studying the epigenetic regulation of replication and functional nuclear architecture. In theory, this construct represents an almost "ideal" expression system for gene therapy. In practice, S/MAR-based vectors stably modify mammalian cells with efficiencies far below those of virus-based constructs. Consequently, they have not yet found application in gene therapy trials. Furthermore, S/MAR vector systems are not trivial to handle and several critical technical issues have to be considered when modifying these vectors for various applications.
Giacosa, Francesco; Janowski, Stanislaus
2016-01-01
We calculate two- and three-body decays of the (lightest) vector glueball into (pseudo)scalar, (axial-)vector, as well as pseudovector and excited vector mesons. By setting the mass of this yet hypothetical vector glueball to 3.8 GeV as predicted by Lattice QCD, many branching ratios can be computed and represent a parameter-free prediction of our approach. We find that the decay mode $\\omega\\pi\\pi$ should be one of the largest (both through the decay chain $\\mathcal{O}\\rightarrow b_{1}\\pi\\rightarrow$ $\\omega\\pi\\pi$ and through the direct coupling $\\mathcal{O}\\rightarrow\\omega\\pi\\pi$)$.$ Similarly, the (direct and indirect) decay into $\\pi KK^{\\ast}(892)$ is sizable. Moreover, the decays into $\\rho\\pi$ and $K^{\\ast}(892)K$ are, although subleading, possible and could play a role in explaining the $\\rho\\pi$ puzzle of the charmonium state $\\psi(2S)$ thank to a (small) mixing with the vector glueball. The vector glueball can be directly formed at the ongoing BESIII experiment as well as at the future PANDA exper...
Containment of arthropod disease vectors.
Scott, Thomas W
2005-01-01
Effective containment of arthropod vectors of infectious diseases is necessary to prevent transmission of pathogens by released, infected vectors and to prevent vectors that escape from establishing populations that subsequently contribute to increased disease. Although rare, past releases illustrate what can go wrong and justify the need for guidelines that minimize risks. An overview of recommendations for insectary facilities, practices, and equipment is provided, and features of four recently published and increasingly rigorous arthropod containment levels (ACLs 1-4) are summarized. ACL-1 is appropriate for research that constitutes the lowest risk level, including uninfected arthropods or vectors that are infected with micro-organisms that do not cause disease in humans, domestic animals, or wildlife. ACL-2 is appropriate for indigenous and exotic arthropods that represent a moderate risk, including vectors infected or suspected of being infected with biosafety level (BSL)-2 infectious agents and arthropods that have been genetically modified in ways that do not significantly affect their fecundity, survival, host preference, or vector competence. ACL-3 is recommended for arthropods that are or may be infected with BSL-3 infectious agents. ACL-3 places greater emphasis on pathogen containment and more restricted access to the insectary than ACL-2. ACL-4 is intended for arthropods that are infected with the most dangerous BSL-4 infectious agents, which can cause life-threatening illness by aerosol or arthropod bite. Adherence to these guidelines will result in laboratory-based arthropod vector research that minimizes risks and results in important new contributions to applied and basic science.
Fan, Zhong-Ying
2016-09-01
In this paper, we consider Einstein gravity coupled to a vector field, either minimally or non-minimally, together with a vector potential of the type V = 2{Λ}_0+1/2{m}^2{A}^2 + {γ}_4{A}^4 . For a simpler non-minimally coupled theory with Λ0 = m = γ4 = 0, we obtain both extremal and non-extremal black hole solutions that are asymptotic to Minkowski space-times. We study the global properties of the solutions and derive the first law of thermodynamics using Wald formalism. We find that the thermodynamical first law of the extremal black holes is modified by a one form associated with the vector field. In particular, due to the existence of the non-minimal coupling, the vector forms thermodynamic conjugates with the graviton mode and partly contributes to the one form modifying the first law. For a minimally coupled theory with Λ0 ≠ 0, we also obtain one class of asymptotically flat extremal black hole solutions in general dimensions. This is possible because the parameters ( m 2 , γ4) take certain values such that V = 0. In particular, we find that the vector also forms thermodynamic conjugates with the graviton mode and contributes to the corresponding first law, although the non-minimal coupling has been turned off. Thus all the extremal black hole solutions that we obtain provide highly non-trivial examples how the first law of thermodynamics can be modified by a either minimally or non-minimally coupled vector field. We also study Gauss-Bonnet gravity non-minimally coupled to a vector and obtain asymptotically flat black holes and Lifshitz black holes.
Project Physics Programmed Instruction, Vectors 1.
Harvard Univ., Cambridge, MA. Harvard Project Physics.
This programmed instruction booklet is an interim version of instructional materials being developed by Harvard Project Physics. It is the first in a series of three booklets on vectors and covers the definitions of vectors and scalars, drawing vector quantities to scale, and negative vectors. For others in this series, see SE 015 550 and SE 015…
Project Physics Programmed Instruction, Vectors 2.
Harvard Univ., Cambridge, MA. Harvard Project Physics.
This is the second of a series of three programmed instruction booklets on vectors developed by Harvard Project Physics. It covers adding two or more vectors together, and finding a third vector that could be added to two given vectors to make a sum of zero. For other booklets in this series, see SE 015 549 and SE 015 551. (DT)
The Duality on Vector Optimization Problems
Institute of Scientific and Technical Information of China (English)
HUANG Long-guang
2012-01-01
Duality framework on vector optimization problems in a locally convex topological vector space are established by using scalarization with a cone-strongly increasing function.The dualities for the scalar convex composed optimization problems and for general vector optimization problems are studied.A general approach for studying duality in vector optimization problems is presented.
A NOTE ON VECTOR CASCADE ALGORITHM
Institute of Scientific and Technical Information of China (English)
Qiu-hui Chen; Jin-zhao Liu; Wen-sheng Zhang
2002-01-01
The focus of this paper is on the relationship between accuracy of multivariate refinable vector and vector cascade algorithm. We show that, if the vector cascade algorithm (1.5) with isotropic dilation converges to a vector-valued function with regularity, then the initial function must satisfy the Strang-Fix conditions.
The biological control of disease vectors.
Okamoto, Kenichi W; Amarasekare, Priyanga
2012-09-21
Vector-borne diseases are common in nature and can have a large impact on humans, livestock and crops. Biological control of vectors using natural enemies or competitors can reduce vector density and hence disease transmission. However, the indirect interactions inherent in host-vector disease systems make it difficult to use traditional pest control theory to guide biological control of disease vectors. This necessitates a conceptual framework that explicitly considers a range of indirect interactions between the host-vector disease system and the vector's biological control agent. Here we conduct a comparative analysis of the efficacy of different types of biological control agents in controlling vector-borne diseases. We report three key findings. First, highly efficient predators and parasitoids of the vector prove to be effective biological control agents, but highly virulent pathogens of the vector also require a high transmission rate to be effective. Second, biocontrol agents can successfully reduce long-term host disease incidence even though they may fail to reduce long-term vector densities. Third, inundating a host-vector disease system with a natural enemy of the vector has little or no effect on reducing disease incidence, but inundating the system with a competitor of the vector has a large effect on reducing disease incidence. The comparative framework yields predictions that are useful in developing biological control strategies for vector-borne diseases. We discuss how these predictions can inform ongoing biological control efforts for host-vector disease systems.
Implementing Bayesian Vector Autoregressions Implementing Bayesian Vector Autoregressions
Directory of Open Access Journals (Sweden)
Richard M. Todd
1988-03-01
Full Text Available Implementing Bayesian Vector Autoregressions This paper discusses how the Bayesian approach can be used to construct a type of multivariate forecasting model known as a Bayesian vector autoregression (BVAR. In doing so, we mainly explain Doan, Littermann, and Sims (1984 propositions on how to estimate a BVAR based on a certain family of prior probability distributions. indexed by a fairly small set of hyperparameters. There is also a discussion on how to specify a BVAR and set up a BVAR database. A 4-variable model is used to iliustrate the BVAR approach.
Vector Encoding in Biochemical Networks
Potter, Garrett; Sun, Bo
Encoding of environmental cues via biochemical signaling pathways is of vital importance in the transmission of information for cells in a network. The current literature assumes a single cell state is used to encode information, however, recent research suggests the optimal strategy utilizes a vector of cell states sampled at various time points. To elucidate the optimal sampling strategy for vector encoding, we take an information theoretic approach and determine the mutual information of the calcium signaling dynamics obtained from fibroblast cells perturbed with different concentrations of ATP. Specifically, we analyze the sampling strategies under the cases of fixed and non-fixed vector dimension as well as the efficiency of these strategies. Our results show that sampling with greater frequency is optimal in the case of non-fixed vector dimension but that, in general, a lower sampling frequency is best from both a fixed vector dimension and efficiency standpoint. Further, we find the use of a simple modified Ornstein-Uhlenbeck process as a model qualitatively captures many of our experimental results suggesting that sampling in biochemical networks is based on a few basic components.
Ensemble Dynamics and Bred Vectors
Balci, Nusret; Restrepo, Juan M; Sell, George R
2011-01-01
We introduce the new concept of an EBV to assess the sensitivity of model outputs to changes in initial conditions for weather forecasting. The new algorithm, which we call the "Ensemble Bred Vector" or EBV, is based on collective dynamics in essential ways. By construction, the EBV algorithm produces one or more dominant vectors. We investigate the performance of EBV, comparing it to the BV algorithm as well as the finite-time Lyapunov Vectors. We give a theoretical justification to the observed fact that the vectors produced by BV, EBV, and the finite-time Lyapunov vectors are similar for small amplitudes. Numerical comparisons of BV and EBV for the 3-equation Lorenz model and for a forced, dissipative partial differential equation of Cahn-Hilliard type that arises in modeling the thermohaline circulation, demonstrate that the EBV yields a size-ordered description of the perturbation field, and is more robust than the BV in the higher nonlinear regime. The EBV yields insight into the fractal structure of th...
Gauge Theories of Vector Particles
Glashow, S. L.; Gell-Mann, M.
1961-04-24
The possibility of generalizing the Yang-Mills trick is examined. Thus we seek theories of vector bosons invariant under continuous groups of coordinate-dependent linear transformations. All such theories may be expressed as superpositions of certain "simple" theories; we show that each "simple theory is associated with a simple Lie algebra. We may introduce mass terms for the vector bosons at the price of destroying the gauge-invariance for coordinate-dependent gauge functions. The theories corresponding to three particular simple Lie algebras - those which admit precisely two commuting quantum numbers - are examined in some detail as examples. One of them might play a role in the physics of the strong interactions if there is an underlying super-symmetry, transcending charge independence, that is badly broken. The intermediate vector boson theory of weak interactions is discussed also. The so-called "schizon" model cannot be made to conform to the requirements of partial gauge-invariance.
Vector bundles on toric varieties
Gharib, Saman
2011-01-01
Following Sam Payne's work, we study the existence problem of nontrivial vector bundles on toric varieties. The first result we prove is that every complete fan admits a nontrivial conewise linear multivalued function. Such functions could potentially be the Chern classes of toric vector bundles. Then we use the results of Corti\\~nas, Haesemeyer, Walker and Weibel to show that the (non-equivariant) Grothendieck group of the toric 3-fold studied by Payne is large, so the variety has a nontrivial vector bundle. Using the same computation, we show that every toric 3-fold X either has a nontrivial line bundle, or there is a finite surjective toric morphism from Y to X, such that Y has a large Grothendieck group.
DEFF Research Database (Denmark)
Holbek, Simon
studies and in vivo. Phantom measurements are compared with their corresponding reference value, whereas the in vivo measurement is validated against the current golden standard for non-invasive blood velocity estimates, based on magnetic resonance imaging (MRI). The study concludes, that a high precision......, if this significant reduction in the element count can still provide precise and robust 3-D vector flow estimates in a plane. The study concludes that the RC array is capable of estimating precise 3-D vector flow both in a plane and in a volume, despite the low channel count. However, some inherent new challenges......For the last decade, the field of ultrasonic vector flow imaging has gotten an increasingly attention, as the technique offers a variety of new applications for screening and diagnostics of cardiovascular pathologies. The main purpose of this PhD project was therefore to advance the field of 3-D...
Skyrmions with vector mesons revisited
Oh, Yongseok
2014-01-01
In order to develop a model that can describe both a single baryon and multi-baryon systems on the same footing, we re-investigate the Skyrme model in a chiral Lagrangian derived from the hidden local symmetry (HLS) up to $O(p^4)$ including the homogeneous Wess-Zumino terms. We use the master formulas that connect the parameters of the HLS Lagrangian and a class of holographic QCD models, which provides a controllable way to determine the low-energy constants of the Lagrangian once the pion decay constant and the vector meson mass are given. Therefore, this model allows us to study the role of vector mesons in the skyrmion structure. We find that the $\\rho$ and $\\omega$ vector mesons have different roles in the skyrmion structure and that the $\\omega$ meson has an important role in the properties of the nucleon.
Quantum contextuality for rational vectors
Cabello, Adan
2010-01-01
The Kochen-Specker theorem states that noncontextual hidden variable models are inconsistent with the quantum predictions for every yes-no question on a qutrit, corresponding to every projector in three dimensions. It has been suggested [D. A. Meyer, Phys. Rev. Lett. 83, 3751 (1999)] that the inconsistency would disappear when we are restricted to projectors on unit vectors with rational components; that noncontextual hidden variables could reproduce the quantum predictions for rational vectors. Here we show that a qutrit state with rational components violates an inequality valid for noncontextual hidden-variable models [A. A. Klyachko et al., Phys. Rev. Lett. 101, 020403 (2008)] using rational projectors. This shows that the inconsistency remains even when using only rational vectors.
DEFF Research Database (Denmark)
Pihl, Michael Johannes
The main purpose of this PhD project is to develop an ultrasonic method for 3D vector flow imaging. The motivation is to advance the field of velocity estimation in ultrasound, which plays an important role in the clinic. The velocity of blood has components in all three spatial dimensions, yet...... conventional methods can estimate only the axial component. Several approaches for 3D vector velocity estimation have been suggested, but none of these methods have so far produced convincing in vivo results nor have they been adopted by commercial manufacturers. The basis for this project is the Transverse...... on the TO fields are suggested. They can be used to optimize the TO method. In the third part, a TO method for 3D vector velocity estimation is proposed. It employs a 2D phased array transducer and decouples the velocity estimation into three velocity components, which are estimated simultaneously based on 5...
Learning with Support Vector Machines
Campbell, Colin
2010-01-01
Support Vectors Machines have become a well established tool within machine learning. They work well in practice and have now been used across a wide range of applications from recognizing hand-written digits, to face identification, text categorisation, bioinformatics, and database marketing. In this book we give an introductory overview of this subject. We start with a simple Support Vector Machine for performing binary classification before considering multi-class classification and learning in the presence of noise. We show that this framework can be extended to many other scenarios such a
Requirements for airborne vector gravimetry
Schwarz, K. P.; Colombo, O.; Hein, G.; Knickmeyer, E. T.
1992-01-01
The objective of airborne vector gravimetry is the determination of the full gravity disturbance vector along the aircraft trajectory. The paper briefly outlines the concept of this method using a combination of inertial and GPS-satellite data. The accuracy requirements for users in geodesy and solid earth geophysics, oceanography and exploration geophysics are then specified. Using these requirements, accuracy specifications for the GPS subsystem and the INS subsystem are developed. The integration of the subsystems and the problems connected with it are briefly discussed and operational methods are indicated that might reduce some of the stringent accuracy requirements.
Vector Theory in Relativistic Thermodynamics
Institute of Scientific and Technical Information of China (English)
刘泽文
1994-01-01
It is pointed out that five defects occur in Planck-Einstein’s relativistic thermodynamics (P-E theory). A vector theory in relativistic thermodynamics (VTRT) is established. Defining the internal energy as a 4-vector, and supposing the entropy and the number of. particles to be invariants we have derived the transformations of all quantities, and subsequently got the Lagrangian and 4-D forms of thermodynamic laws. In order to test the new theory, several exact solutions with classical limits are given. The VTRT is free from the defects of the P-E theory.
Scalar Calibration of Vector Magnetometers
DEFF Research Database (Denmark)
Merayo, José M.G.; Brauer, Peter; Primdahl, Fritz;
2000-01-01
The calibration parameters of a vector magnetometer are estimated only by the use of a scalar reference magnetometer. The method presented in this paper differs from those previously reported in its linearized parametrization. This allows the determination of three offsets or signals in the absence...
Vector ecology of equine piroplasmosis
Equine piroplasmosis (EP) is a disease of equidae including horses, donkeys, mules and zebras caused by either of two protozoan parasites, Theileria equi or Babesia caballi. These parasites are biologically transmitted between hosts via tick-vectors and although they have inherent differences, they ...
SCALAR AND VECTOR IN COMPULATION
Directory of Open Access Journals (Sweden)
Valery F. Ochkov
2013-01-01
Full Text Available The article deals with two fundamental data types – scalar and vector (array, without the ability of working with them one cannot solve using computer school or university tasks in mathematics, physics, chemistry and other technical training courses. Some fundamentals of teaching computer science at school and university are covered as well.
Vector-valued fuzzy multifunctions
Directory of Open Access Journals (Sweden)
Ismat Beg
2001-01-01
Full Text Available Some of the properties of vector-valued fuzzy multifunctions are studied. The notion of sum fuzzy multifunction, convex hull fuzzy multifunction, close convex hull fuzzy multifunction, and upper demicontinuous are given, and some of the properties of these fuzzy multifunctions are investigated.
Portfolio Analysis for Vector Calculus
Kaplan, Samuel R.
2015-01-01
Classic stock portfolio analysis provides an applied context for Lagrange multipliers that undergraduate students appreciate. Although modern methods of portfolio analysis are beyond the scope of vector calculus, classic methods reinforce the utility of this material. This paper discusses how to introduce classic stock portfolio analysis in a…
Sparse Matrix Vector Processing Formats
Stathis, P.T.
2004-01-01
In this dissertation we have identified vector processing shortcomings related to the efficient storing and processing of sparse matrices. To alleviate existent problems we propose two storage formats denoted as Block Based Compression Storage (BBCS) format and Hierarchical Sparse Matrix (HiSM) stor
Bifurcations of optimal vector fields
Kiseleva, T.; Wagener, F.
2015-01-01
We study the structure of the solution set of a class of infinite-horizon dynamic programming problems with one-dimensional state spaces, as well as their bifurcations, as problem parameters are varied. The solutions are represented as the integral curves of a multivalued optimal vector field on sta
Phlebotomine Vectors of Human Disease.
1983-12-30
different. We refrain from naming this specimen until more material becomes available. 12. Lutzomyia olmeca bicolor Fairchild and Theodor 1971...Castillo (1958) and Arzube (1960). Lutzomyia olmeca bicolor is the suspected vector of Leishmania mexicana aristedesi among rodents and marsupials in
Vector-meson dominance revisited
Directory of Open Access Journals (Sweden)
Terschlüsen Carla
2012-12-01
Full Text Available The interaction of mesons with electromagnetism is often well described by the concept of vector-meson dominance (VMD. However, there are also examples where VMD fails. A simple chiral Lagrangian for pions, rho and omega mesons is presented which can account for the respective agreement and disagreement between VMD and phenomenology in the sector of light mesons.
Phase transitions in Vector Quantization
Witoelar, Aree; Ghosh, Anarta; Biehl, Michael; Verleysen, Michel
2008-01-01
We study Winner-Takes-All and rank based Vector Quantization along the lines of the statistical physics of off-line learning. Typical behavior of the system is obtained within a model where high-dimensional training data are drawn from a mixture of Gaussians. The analysis becomes exact in the simpli
Parallel Sparse Matrix - Vector Product
DEFF Research Database (Denmark)
Alexandersen, Joe; Lazarov, Boyan Stefanov; Dammann, Bernd
This technical report contains a case study of a sparse matrix-vector product routine, implemented for parallel execution on a compute cluster with both pure MPI and hybrid MPI-OpenMP solutions. C++ classes for sparse data types were developed and the report shows how these class can be used...
The consequences of poor vectorization
CERN. Geneva
2016-01-01
This talk briefly discusses the vectorization problem and how it impacts scientific and engineering systems. A simple cost model of designing such system in context of different phases of software lifetime is considered. Finally a concept for scalable solution is presented.
Vector Bundles over Elliptic Fibrations
Friedman, R; Witten, Edward; Friedman, Robert; Morgan, John W.; Witten, Edward
1997-01-01
This paper gives various methods for constructing vector bundles over elliptic curves and more generally over families of elliptic curves. We construct universal families over generalized elliptic curves via spectral cover methods and also by extensions, and then give a relative version of the construction in families. We give various examples and make Chern class computations.
Large N Expansion. Vector Models
Nissimov, E; Nissimov, Emil; Pacheva, Svetlana
2006-01-01
Preliminary version of a contribution to the "Quantum Field Theory. Non-Perturbative QFT" topical area of "Modern Encyclopedia of Mathematical Physics" (SELECTA), eds. Aref'eva I, and Sternheimer D, Springer (2007). Consists of two parts - "main article" (Large N Expansion. Vector Models) and a "brief article" (BPHZL Renormalization).
Vector variational inequalities and their relations with vector optimization
Directory of Open Access Journals (Sweden)
Surjeet Kaur Suneja
2014-01-01
Full Text Available In this paper, K- quasiconvex, K- pseudoconvex and other related functions have been introduced in terms of their Clarke subdifferentials, where is an arbitrary closed convex, pointed cone with nonempty interior. The (strict, weakly -pseudomonotonicity, (strict K- naturally quasimonotonicity and K- quasimonotonicity of Clarke subdifferential maps have also been defined. Further, we introduce Minty weak (MVVIP and Stampacchia weak (SVVIP vector variational inequalities over arbitrary cones. Under regularity assumption, we have proved that a weak minimum solution of vector optimization problem (VOP is a solution of (SVVIP and under the condition of K- pseudoconvexity we have obtained the converse for MVVIP (SVVIP. In the end we study the interrelations between these with the help of strict K-naturally quasimonotonicity of Clarke subdifferential map.
Vector-Boson Fusion and Vector-Boson Scattering
Rauch, Michael
2016-01-01
Vector-boson fusion and vector-boson scattering are an important class of processes for the Large Hadron Collider at CERN. It is characterized by two high-energetic jets in the forward regions of the detector and reduced jet activity in the central region. The higher center-of-mass energy during the current and subsequent runs strongly boosts the sensitivity in these processes and allows to test the predictions of the Standard Model to a high precision. In this review, we first present the main phenomenological features of vector-boson fusion and scattering processes. Then we discuss the effects of higher-order corrections, which are available at NLO QCD for all processes and up to N3LO QCD and NLO electro-weak for VBF-H production. An additional refinement is the addition of parton-shower effects, where recently a lot of progress has been made. The appearance of triple and quartic gauge vertices in the production processes enables us to probe anomalous gauge couplings. We introduce and compare the different ...
On third order integrable vector Hamiltonian equations
Meshkov, A. G.; Sokolov, V. V.
2017-03-01
A complete list of third order vector Hamiltonian equations with the Hamiltonian operator Dx having an infinite series of higher conservation laws is presented. A new vector integrable equation on the sphere is found.
SYSTEM OF GENERALIZED VECTOR VARIATIONAL INEQUALITIES
Institute of Scientific and Technical Information of China (English)
Fang Yaping; Huang Nanjing
2005-01-01
In this paper, the authors introduce and study system of generalized vector variational inequalities. Under suitable conditions, the existence of solutions for system of generalized vector variational inequalities is presented by Kakutani-Fan-Glicksberg fixed point theorem.
Symbolic Vector Analysis in Plasma Physics
Energy Technology Data Exchange (ETDEWEB)
Qin, H.; Tang, W.M.; Rewoldt, G.
1997-10-09
Many problems in plasma physics involve substantial amounts of analytical vector calculation. The complexity usually originates from both the vector operations themselves and the choice of underlying coordinate system. A computer algebra package for symbolic vector analysis in general coordinate systems, General Vector Analysis (GVA), is developed using Mathematica. The modern viewpoint for 3D vector calculus, differential forms on 3-manifolds, is adopted to unify and systematize the vector calculus operations in general coordinate systems. This package will benefit physicists and applied mathematicians in their research where complicated vector analysis is required. It will not only save a huge amount of human brain-power and dramatically improve accuracy, but this package will also be an intelligent tool to assist researchers in finding the right approaches to their problems. Several applications of this symbolic vector analysis package to plasma physics are also given.
Symbolic Vector Analysis in Plasma Physics
Energy Technology Data Exchange (ETDEWEB)
Qin, H.; Rewoldt, G.; Tang, W.M.
1997-10-01
Many problems in plasma physics involve substantial amounts of analytical vector calculation. The complexity usually originates from both the vector operations themselves and the choice of underlying coordinate system. A computer algebra package for symbolic vector analysis in general coordinate systems, GeneralVectorAnalysis (GVA), is developed using Mathematica. The modern viewpoint for 3D vector calculus, differential forms on 3-manifolds, is adopted to unify and systematize the vector calculus operations in general coordinate systems. This package will benefit physicists and applied mathematicians in their research where complicated vector analysis is required. It will not only save a huge amount of human brain-power and dramatically improve accuracy, but this package will also be an intelligent tool to assist researchers in finding the right approaches to their problems. Several applications of this symbolic vector analysis package to plasma physics are also given.
Vectors and translations in mathematics and physics
Dorier, Jean-Luc
2016-01-01
In mathematics, students learn about vectors and translation, in physics they model forces, speed, acceleration, etc. with vectors and study movements of translation. Do they make the connection between these concepts introduced in different disciplines or do they put things in separate boxes? In this paper we will start with some partial considerations on the history of vectors and we will give some references. Then we will show some examples of naïve illustrations of vectors from physics in...
NEVILLE-TYPE VECTOR VALUED RATIONAL INTERPOLANTS
Institute of Scientific and Technical Information of China (English)
陈之兵; 顾传青; 徐晨
2004-01-01
A new kind of vector valued rational interpolants is established by means of Samelson inverse, with scalar numerator and vector valued denominator. It is essen tially different from that of Graves-Morris(1983), where the interpolants are constructed by Thiele-type continued fractions with vector valued numerator and scalar denominator. The new approach is more suitable to calculate the value of a vector valued function for a given point. And an error formula is also given and proven.
Gene targeting with retroviral vectors
Energy Technology Data Exchange (ETDEWEB)
Ellis, J.; Bernstein, A. (Toronto Univ., ON (Canada))
1989-04-01
The authors have designed and constructed integration-defective retroviral vectors to explore their potential for gene targeting in mammalian cells. Two nonoverlapping deletion mutants of the bacterial neomycin resistance (neo) gene were used to detect homologous recombination events between viral and chromosomal sequences. Stable neo gene correction events were selected at a frequency of approximately 1 G418/sup r/ cell per 3 x 10/sup 6/ infected cells. Analysis of the functional neo gene in independent targeted cell clones indicated that unintegrated retroviral linear DNA recombined with the target by gene conversion for variable distances into regions of nonhomology. In addition, transient neo gene correction events which were associated with the complete loss of the chromosomal target sequences were observed. These results demonstrated that retroviral vectors can recombine with homologous chromosomal sequences in rodent and human cells.
Clinical applications of power vectors.
Miller, Joseph M
2009-06-01
The study of infant vision is closely coupled to the study of the refraction, change in refraction over time, and the effect of spectacle correction on visual development. Frequently, reports are limited to descriptions of spherical equivalent or cylinder power without regard to axis, as data are frequently collected in the clinical format of sphere, cylinder, and axis (S, C, A). Conversion from clinical notation to a power vector representation of refraction allows unambiguous description of how refractions change over time and differ between repeated measurements. This article presents a series of examples of Microsoft Excel spreadsheet formulas that make the conversion from clinical notation to power vector format, and provides examples of useful applications of these methods.
ELVIS - ELectromagnetic Vector Information Sensor
Bergman, J E S; Thidé, B; Ananthakrishnan, S; Wahlund, J E; Karlsson, R L; Puccio, W; Carozzi, T D; Kale, P
2005-01-01
The ELVIS instrument was recently proposed by the authors for the Indian Chandrayaan-1 mission to the Moon and is presently under consideration by the Indian Space Research Organisation (ISRO). The scientific objective of ELVIS is to explore the electromagnetic environment of the moon. ELVIS samples the full three-dimensional (3D) electric field vector, E(x,t), up to 18 MHz, with selective Nyqvist frequency bandwidths down to 5 kHz, and one component of the magnetic field vector, B(x,t), from a few Hz up to 100 kHz.As a transient detector, ELVIS is capable of detecting pulses with a minimum pulse width of 5 ns. The instrument comprises three orthogonal electric dipole antennas, one magnetic search coil antenna and a four-channel digital sampling system, utilising flexible digital down conversion and filtering together with state-of-the-art onboard digital signal processing.
Lentiviral vectors in cancer immunotherapy.
Oldham, Robyn Aa; Berinstein, Elliot M; Medin, Jeffrey A
2015-01-01
Basic science advances in cancer immunotherapy have resulted in various treatments that have recently shown success in the clinic. Many of these therapies require the insertion of genes into cells to directly kill them or to redirect the host's cells to induce potent immune responses. Other analogous therapies work by modifying effector cells for improved targeting and enhanced killing of tumor cells. Initial studies done using γ-retroviruses were promising, but safety concerns centered on the potential for insertional mutagenesis have highlighted the desire to develop other options for gene delivery. Lentiviral vectors (LVs) have been identified as potentially more effective and safer alternative delivery vehicles. LVs are now in use in clinical trials for many different types of inherited and acquired disorders, including cancer. This review will discuss current knowledge of LVs and the applications of this viral vector-based delivery vehicle to cancer immunotherapy.
Ultrasonic Dynamic Vector Stress Sensor
Heyman, Joseph S.; Froggatt, Mark
1992-01-01
Stress inferred from measurements in specimens rather than in bonded gauges. Ultrasonic dynamic vector stress sensor (UDVSS) measures changes in dynamic directional stress occurring in material or structure at location touched by device when material or structure put under cyclic load. Includes phase-locked loop, synchronous amplifier, and contact probe. Useful among manufacturers of aerospace and automotive structures for stress testing and evaluation of designs.
Biological rhythms and vector insects
Directory of Open Access Journals (Sweden)
Mirian David Marques
2013-01-01
Full Text Available The adjustment of all species, animals and plants, to the Earth’s cyclic environments is ensured by their temporal organisation. The relationships between parasites, vectors and hosts rely greatly upon the synchronisation of their biological rhythms, especially circadian rhythms. In this short note, parasitic infections by Protozoa and by microfilariae have been chosen as examples of the dependence of successful transmission mechanisms on temporal components.
Vector and tensor analysis with applications
Borisenko, A I; Silverman, Richard A
1979-01-01
Concise and readable, this text ranges from definition of vectors and discussion of algebraic operations on vectors to the concept of tensor and algebraic operations on tensors. It also includes a systematic study of the differential and integral calculus of vector and tensor functions of space and time. Worked-out problems and solutions. 1968 edition.
Project Physics Programmed Instruction, Vectors 3.
Harvard Univ., Cambridge, MA. Harvard Project Physics.
This is the third of a series of three programmed instruction booklets on vectors developed by Harvard Project Physics. Separating vectors into components and obtaining a vector from its components are the topics covered. For other booklets in this series, see SE 015 549 and SE 015 550. (DT)
Some Remarks on a Generalized Vector Product
Acosta-Humánez, Primitivo B; Núñez, Reinaldo
2011-01-01
In this paper we use a generalized vector product to construct an exterior form $\\wedge :(\\mathbb{R}^{n}) ^{k}\\to \\mathbb{R}^{\\binom{n}{k}}$, where $\\binom{n}{k}=\\frac{n!}{(n-k)!k!}$, $k\\leq n$. Finally, for $n=k-1$ we introduce the reversing operation to study this generalized vector product over palindromic and antipalindromic vectors.
Vector Fields and Flows on Differentiable Stacks
DEFF Research Database (Denmark)
A. Hepworth, Richard
2009-01-01
This paper introduces the notions of vector field and flow on a general differentiable stack. Our main theorem states that the flow of a vector field on a compact proper differentiable stack exists and is unique up to a uniquely determined 2-cell. This extends the usual result on the existence...... of vector fields....
On the Distribution of Norm of Vector Projection and Rejection of Two Complex Normal Random Vectors
Directory of Open Access Journals (Sweden)
Mehdi Maleki
2015-01-01
Full Text Available Vector projection and vector rejection are highly common and useful operations in mathematics, information theory, and signal processing. In this paper, we find the distribution of the norm of projection and rejection vectors when the original vectors are standard complex normally distributed.
Problems and worked solutions in vector analysis
Shorter, LR
2014-01-01
""A handy book like this,"" noted The Mathematical Gazette, ""will fill a great want."" Devoted to fully worked out examples, this unique text constitutes a self-contained introductory course in vector analysis for undergraduate and graduate students of applied mathematics.Opening chapters define vector addition and subtraction, show how to resolve and determine the direction of two or more vectors, and explain systems of coordinates, vector equations of a plane and straight line, relative velocity and acceleration, and infinitely small vectors. The following chapters deal with scalar and vect
DBSC-Based Grayscale Line Image Vectorization
Institute of Scientific and Technical Information of China (English)
Konstantin Melikhov; Feng Tian; Jie Qiu; Quan Chen; Hock Soon Seah
2006-01-01
Vector graphics plays an important role in computer animation and imaging technologies. However present techniques and tools cannot fully replace traditional pencil and paper. Additionally, vector representation of an image is not always available. There is not yet a good solution for vectorizing a picture drawn on a paper. This work attempts to solve the problem of vectorizing grayscale line drawings. The solution proposed uses Disk B-Spline curves to represent strokes of an image in vector form. The algorithm builds a vector representation from a grayscale raster image, which can be a scanned picture for instance. The proposed method uses a Gaussian sliding window to calculate skeleton and perceptive width of a stroke. As a result of vectorization, the given image is represented by a set of Disk B-Spline curves.
The vector algebra war: A historical perspective
Chappell, James M; Hartnett, John G; Abbott, Derek
2015-01-01
There are a wide variety of different vector formalisms currently utilized in science. For example, Gibbs three-vectors, spacetime four-vectors, complex spinors for quantum mechanics, quaternions used for rigid body rotations and Clifford multivectors. With such a range of vector formalisms in use, it thus appears that there is as yet no general agreement on a vector formalism suitable for the whole of science. This surprising situation exists today, despite the fact that one of the main goals of nineteenth century science was to correctly describe vectors and the algebra of three-dimensional space. This situation has also had the unfortunate consequence of fragmenting knowledge across many disciplines and requiring a very significant amount of time and effort in learning the different formalisms. We thus review historically the development of our various vector systems and conclude that the Clifford algebra multivector fulfills the goal of correctly describing vectorial quantities in three dimensions.
Some theoretical comparisons of refined Ritz vectors and Ritz vectors
Institute of Scientific and Technical Information of China (English)
JIA Zhongxiao
2004-01-01
Refined projection methods proposed by the author have received attention internationally. We are concerned with a conventional projection method and its refined counterpart for computing approximations to a simple eigenpair (λ,x)of a large matrix A. Given a subspace w that contains anapproximation to x, these two methods compute approximations(μ(x~)) and (μ(x^)) to (λ,x),respectively. We establish three results. First, the refinedeigenvector approximation or simply the refined Ritz vector (x^) is unique as the deviation of x from w approaches zero if λ is simple. Second, interms of residual norm of the refined approximate eigenpair (μ,(x^)), we derive lower and upper bounds for the sine of the angle betweenthe Ritz vector (x~) and the refined eigenvector approximation (x^), and we prove that (x~)≠(x^) unless (x^)=x. Third, we establish relationships between theresidual norm ‖A(x~)-μ(x^)‖ of the conventionalmethods and the residual norm ‖A(x^)-μ(x^)‖ of therefined methods, and we show that the latter is always smallerthan the former if (μ,(x^)) is not an exact eigenpair ofA, indicating that the refined projection method is superiorto the corresponding conventional counterpart.
Some theoretical comparisons of refined Ritz vectors and Ritz vectors
Institute of Scientific and Technical Information of China (English)
JIA; Zhongxiao
2004-01-01
Refined projection methods proposed by the author have received attention internationally. We are concerned with a conventional projection method and its refined counterpart for computing approximations to a simple eigenpair (λ,x)of a large matrix A. Given a subspace w that contains anapproximation to x, these two methods compute approximations(μ(x~)) and (μ(x)) to (λ,x),respectively. We establish three results. First, the refinedeigenvector approximation or simply the refined Ritz vector (x) is unique as the deviation of x from w approaches zero if λ is simple. Second, interms of residual norm of the refined approximate eigenpair (μ,(x)), we derive lower and upper bounds for the sine of the angle betweenthe Ritz vector (x~) and the refined eigenvector approximation (x), and we prove that (x~)≠(x) unless (x)=x. Third, we establish relationships between theresidual norm ‖A(x~)-μ(x)‖ of the conventionalmethods and the residual norm ‖A(x)-μ(x)‖ of therefined methods, and we show that the latter is always smallerthan the former if (μ,(x)) is not an exact eigenpair ofA, indicating that the refined projection method is superiorto the corresponding conventional counterpart.
Vector meson electroproduction in QCD
Lu, Juan; Cai, Xian-Hao; Zhou, Li-Juan
2012-08-01
Based on the generalized QCD vector meson dominance model, we study the electroproduction of a vector meson off a proton in the QCD inspired eikonalized model. Numerical calculations for the total cross section σtot and differential cross section dσ/dt are performed for ρ, ω and varphi meson electroproduction in this paper. Since gluons interact among themselves (self-interaction), two gluons can form a glueball with quantum numbers IG, JPC = 0+,2++, decay width Γt ≈ 100 MeV, and mass of mG = 2.23 GeV. The three gluons can form a three-gluon colorless bound state with charge conjugation quantum number C = -1, called the Odderon. The mediators of interactions between projectiles (the quark and antiquark pair fluctuated from the virtual photon) and the proton target (a three-quark system) are the tensor glueball and the Odderon. Our calculated results in the tensor glueball and Odderon exchange model fit to the existing data successfully, which evidently shows that our present QCD mechanism is a good description of meson electroproduction off a proton. It should be emphasized that our mechanism is different from the theoretical framework of Block et al. We also believe that the present study and its success are important for the investigation of other vector meson electro- and photoproduction at high energies, as well as for searching for new particles such as tensor glueballs and Odderons, which have been predicted by QCD and the color glass condensate model (CGC). Therefore, in return, it can test the validity of QCD and the CGC model.
Vector meson electroproduction in QCD
Institute of Scientific and Technical Information of China (English)
LU Juan; CAI Xian-Hao; ZHOU Li-Juan
2012-01-01
Based on the generalized QCD vector meson dominance model,we study the electroproduction of a vector meson off a proton in the QCD inspired eikonalized model.Numerical calculations for the total cross section σtot and differential cross section dσ/dt are performed for p,ω and φ meson electroproduction in this paper.Since gluons interact among themselves (self-interaction),two gluons can form a glueball with quantum numbers IG,JPC =0+,2++,decay width Γt ≈ 100 MeV,and mass of mG=2.23 GeV.The three gluons can form a three-gluon colorless bound state with charge conjugation quantum number C =-1,called the Odderon.The mediators of interactions between projectiles (the quark and antiquark pair fluctuated from the virtual photon) and the proton target (a three-quark system) are the tensor glueball and the Odderon.Our calculated results in the tensor glueball and Odderon exchange model fit to the existing data successfully,which evidently shows that our present QCD mechanism is a good description of meson electroproduction off a proton.It should be emphasized that our mechanism is different from the theoretical framework of Block et al.We also believe that the present study and its success are important for the investigation of other vector meson electro- and photoproduction at high energies,as well as for searching for new particles such as tensor glueballs and Odderons,which have been predicted by QCD and the color glass condensate model (CGC).Therefore,in return,it can test the validity of QCD and the CGC model.
On Weighted Support Vector Regression
DEFF Research Database (Denmark)
Han, Xixuan; Clemmensen, Line Katrine Harder
2014-01-01
We propose a new type of weighted support vector regression (SVR), motivated by modeling local dependencies in time and space in prediction of house prices. The classic weights of the weighted SVR are added to the slack variables in the objective function (OF‐weights). This procedure directly...... the differences and similarities of the two types of weights by demonstrating the connection between the Least Absolute Shrinkage and Selection Operator (LASSO) and the SVR. We show that an SVR problem can be transformed to a LASSO problem plus a linear constraint and a box constraint. We demonstrate...
Probability Ranking in Vector Spaces
Melucci, Massimo
2011-01-01
The Probability Ranking Principle states that the document set with the highest values of probability of relevance optimizes information retrieval effectiveness given the probabilities are estimated as accurately as possible. The key point of the principle is the separation of the document set into two subsets with a given level of fallout and with the highest recall. The paper introduces the separation between two vector subspaces and shows that the separation yields a more effective performance than the optimal separation into subsets with the same available evidence, the performance being measured with recall and fallout. The result is proved mathematically and exemplified experimentally.
Nonviral Vectors for Gene Delivery
Baoum, Abdulgader Ahmed
2011-12-01
The development of nonviral vectors for safe and efficient gene delivery has been gaining considerable attention recently. An ideal nonviral vector must protect the gene against degradation by nuclease in the extracellular matrix, internalize the plasma membrane, escape from the endosomal compartment, unpackage the gene at some point and have no detrimental effects. In comparison to viruses, nonviral vectors are relatively easy to synthesize, less immunogenic, low in cost, and have no limitation in the size of a gene that can be delivered. Significant progress has been made in the basic science and applications of various nonviral gene delivery vectors; however, the majority of nonviral approaches are still inefficient and often toxic. To this end, two nonviral gene delivery systems using either biodegradable poly(D,L-lactide- co-glycolide) (PLG) nanoparticles or cell penetrating peptide (CPP) complexes have been designed and studied using A549 human lung epithelial cells. PLG nanoparticles were optimized for gene delivery by varying particle surface chemistry using different coating materials that adsorb to the particle surface during formation. A variety of cationic coating materials were studied and compared to more conventional surfactants used for PLG nanoparticle fabrication. Nanoparticles (˜200 nm) efficiently encapsulated plasmids encoding for luciferase (80-90%) and slowly released the same for two weeks. After a delay, moderate levels of gene expression appeared at day 5 for certain positively charged PLG particles and gene expression was maintained for at least two weeks. In contrast, gene expression mediated by polyethyleneimine (PEI) ended at day 5. PLG particles were also significantly less cytotoxic than PEI suggesting the use of these vehicles for localized, sustained gene delivery to the pulmonary epithelium. On the other hand, a more simple method to synthesize 50-200 nm complexes capable of high transfection efficiency or high gene knockdown was
Vector-tensor and vector-vector decay amplitude analysis of B0-->phiK*0.
Aubert, B; Bona, M; Boutigny, D; Couderc, F; Karyotakis, Y; Lees, J P; Poireau, V; Tisserand, V; Zghiche, A; Grauges, E; Palano, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Battaglia, M; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Gill, M S; Groysman, Y; Jacobsen, R G; Kadyk, J A; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Pegna, D Lopes; Lynch, G; Mir, L M; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, M T; Wenzel, W A; Sanchez, P del Amo; Barrett, M; Ford, K E; Harrison, T J; Hart, A J; Hawkes, C M; Watson, A T; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schroeder, T; Steinke, M; Boyd, J T; Burke, J P; Cottingham, W N; Walker, D; Asgeirsson, D J; Cuhadar-Donszelmann, T; Fulsom, B G; Hearty, C; Knecht, N S; Mattison, T S; McKenna, J A; Khan, A; Kyberd, P; Saleem, M; Sherwood, D J; Teodorescu, L; Blinov, V E; Bukin, A D; Druzhinin, V P; Golubev, V B; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Todyshev, K Yu; Best, D S; Bondioli, M; Bruinsma, M; Chao, M; Curry, S; Eschrich, I; Kirkby, D; Lankford, A J; Lund, P; Mandelkern, M; Roethel, W; Stoker, D P; Abachi, S; Buchanan, C; Foulkes, S D; Gary, J W; Long, O; Shen, B C; Wang, K; Zhang, L; Hadavand, H K; Hill, E J; Paar, H P; Rahatlou, S; Sharma, V; Berryhill, J W; Campagnari, C; Cunha, A; Dahmes, B; Hong, T M; Kovalskyi, D; Richman, J D; Beck, T W; Eisner, A M; Flacco, C J; Heusch, C A; Kroseberg, J; Lockman, W S; Nesom, G; Schalk, T; Schumm, B A; Seiden, A; Spradlin, P; Williams, D C; Wilson, M G; Albert, J; Chen, E; Cheng, C H; Dvoretskii, A; Fang, F; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Mancinelli, G; Meadows, B T; Mishra, K; Sokoloff, M D; Blanc, F; Bloom, P C; Chen, S; Ford, W T; Hirschauer, J F; Kreisel, A; Nagel, M; Nauenberg, U; Olivas, A; Ruddick, W O; Smith, J G; Ulmer, K A; Wagner, S R; Zhang, J; Chen, A; Eckhart, E A; Soffer, A; Toki, W H; Wilson, R J; Winklmeier, F; Zeng, Q; Altenburg, D D; Feltresi, E; Hauke, A; Jasper, H; Merkel, J; Petzold, A; Spaan, B; Brandt, T; Klose, V; Lacker, H M; Mader, W F; Nogowski, R; Schubert, J; Schubert, K R; Schwierz, R; Sundermann, J E; Volk, A; Bernard, D; Bonneaud, G R; Latour, E; Thiebaux, Ch; Verderi, M; Clark, P J; Gradl, W; Muheim, F; Playfer, S; Robertson, A I; Xie, Y; Andreotti, M; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Petrella, A; Piemontese, L; Prencipe, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Finocchiaro, G; Pacetti, S; Patteri, P; Peruzzi, I M; Piccolo, M; Rama, M; Zallo, A; Buzzo, A; Contri, R; Vetere, M Lo; Macri, M M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Brandenburg, G; Chaisanguanthum, K S; Lee, C L; Morii, M; Wu, J; Dubitzky, R S; Marks, J; Schenk, S; Uwer, U; Bard, D J; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Flack, R L; Nash, J A; Nikolich, M B; Vazquez, W Panduro; Behera, P K; Chai, X; Charles, M J; Mallik, U; Meyer, N T; Ziegler, V; Cochran, J; Crawley, H B; Dong, L; Eyges, V; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Gao, Y; Gritsan, A V; Guo, Z J; Denig, A G; Fritsch, M; Schott, G; Arnaud, N; Davier, M; Grosdidier, G; Höcker, A; Lepeltier, V; Diberder, F Le; Lutz, A M; Oyanguren, A; Pruvot, S; Rodier, S; Roudeau, P; Schune, M H; Serrano, J; Stocchi, A; Wang, W F; Wormser, G; Lange, D J; Wright, D M; Chavez, C A; Forster, I J; Fry, J R; Gabathuler, E; Gamet, R; George, K A; Hutchcroft, D E; Payne, D J; Schofield, K C; Touramanis, C; Bevan, A J; Clarke, C K; Lodovico, F Di; Menges, W; Sacco, R; Cowan, G; Flaecher, H U; Hopkins, D A; Jackson, P S; McMahon, T R; Salvatore, F; Wren, A C; Brown, D N; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Chia, Y M; Edgar, C L; Lafferty, G D; Naisbit, M T; Williams, J C; Yi, J I; Chen, C; Hulsbergen, W D; Jawahery, A; Lae, C K; Roberts, D A; Simi, G; Blaylock, G; Dallapiccola, C; Hertzbach, S S; Li, X; Moore, T B; Saremi, S; Staengle, H; Cowan, R; Sciolla, G; Sekula, S J; Spitznagel, M; Taylor, F; Yamamoto, R K; Kim, H; McLachlin, S E; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Côté, D; Simard, M; Taras, P; Viaud, F B; Nicholson, H; Cavallo, N; Nardo, G De; Fabozzi, F; Gatto, C; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; Snoek, H L; Jessop, C P; Losecco, J M; Benelli, G; Corwin, L A; Gan, K K; Honscheid, K; Hufnagel, D; Jackson, P D; Kagan, H; Kass, R; Rahimi, A M; Regensburger, J J; Ter-Antonyan, R; Wong, Q K; Blount, N L; Brau, J; Frey, R; Igonkina, O; Kolb, J A; Lu, M; Potter, C T; Rahmat, R; Sinev, N B; Strom, D; Strube, J; Torrence, E; Gaz, A; Margoni, M; Morandin, M; Pompili, A; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; Buono, L Del; de la Vaissière, Ch; Hamon, O; Hartfiel, B L; Leruste, Ph; Malclès, J; Ocariz, J; Roos, L; Therin, G; Gladney, L; Biasini, M; Covarelli, R; Angelini, C; Batignani, G; Bettarini, S; Bucci, F; Calderini, G; Carpinelli, M; Cenci, R; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Mazur, M A; Morganti, M; Neri, N; Paoloni, E; Rizzo, G; Walsh, J J; Haire, M; Judd, D; Wagoner, D E; Biesiada, J; Danielson, N; Elmer, P; Lau, Y P; Lu, C; Olsen, J; Smith, A J S; Telnov, A V; Bellini, F; Cavoto, G; D'Orazio, A; del Re, D; Marco, E Di; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Gioi, L Li; Mazzoni, M A; Morganti, S; Piredda, G; Polci, F; Tehrani, F Safai; Voena, C; Ebert, M; Schröder, H; Waldi, R; Adye, T; Franek, B; Olaiya, E O; Ricciardi, S; Wilson, F F; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; de Monchenault, G Hamel; Kozanecki, W; Legendre, M; Vasseur, G; Yèche, Ch; Zito, M; Chen, X R; Liu, H; Park, W; Purohit, M V; Wilson, J R; Allen, M T; Aston, D; Bartoldus, R; Bechtle, P; Berger, N; Claus, R; Coleman, J P; Convery, M R; Dingfelder, J C; Dorfan, J; Dubois-Felsmann, G P; Dujmic, D; Dunwoodie, W; Field, R C; Glanzman, T; Gowdy, S J; Graham, M T; Grenier, P; Halyo, V; Hast, C; Hryn'ova, T; Innes, W R; Kelsey, M H; Kim, P; Leith, D W G S; Li, S; Luitz, S; Luth, V; Lynch, H L; Macfarlane, D B; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Pulliam, T; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Snyder, A; Stelzer, J; Su, D; Sullivan, M K; Suzuki, K; Swain, S K; Thompson, J M; Va'vra, J; van Bakel, N; Wagner, A P; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wittgen, M; Wright, D H; Wulsin, H W; Yarritu, A K; Yi, K; Young, C C; Burchat, P R; Edwards, A J; Majewski, S A; Petersen, B A; Wilden, L; Ahmed, S; Alam, M S; Bula, R; Ernst, J A; Jain, V; Pan, B; Saeed, M A; Wappler, F R; Zain, S B; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Ritchie, J L; Satpathy, A; Schilling, C J; Schwitters, R F; Izen, J M; Lou, X C; Ye, S; Bianchi, F; Gallo, F; Gamba, D; Bomben, M; Bosisio, L; Cartaro, C; Cossutti, F; Ricca, G Della; Dittongo, S; Lanceri, L; Vitale, L; Azzolini, V; Lopez-March, N; Martinez-Vidal, F; Banerjee, Sw; Bhuyan, B; Brown, C M; Fortin, D; Hamano, K; Kowalewski, R; Nugent, I M; Roney, J M; Sobie, R J; Back, J J; Harrison, P F; Latham, T E; Mohanty, G B; Pappagallo, M; Band, H R; Chen, X; Cheng, B; Dasu, S; Datta, M; Flood, K T; Hollar, J J; Kutter, P E; Mellado, B; Mihalyi, A; Pan, Y; Pierini, M; Prepost, R; Wu, S L; Yu, Z; Neal, H
2007-02-02
We perform an amplitude analysis of the decays B(0)-->phiK*(2)(1430)(0), phiK*(892)(0), and phi(Kpi)(0)(S-wave) with a sample of about 384x10(6) BB[over ] pairs recorded with the BABAR detector. The fractions of longitudinal polarization f(L) of the vector-tensor and vector-vector decay modes are measured to be 0.853(-0.069+0.061)+/-0.036 and 0.506+/-0.040+/-0.015, respectively. Overall, twelve parameters are measured for the vector-vector decay and seven parameters for the vector-tensor decay, including the branching fractions and parameters sensitive to CP violation.
Therapeutic and prophylactic applications of alphavirus vectors.
Atkins, Gregory J; Fleeton, Marina N; Sheahan, Brian J
2008-11-11
Alphavirus vectors are high-level, transient expression vectors for therapeutic and prophylactic use. These positive-stranded RNA vectors, derived from Semliki Forest virus, Sindbis virus and Venezuelan equine encephalitis virus, multiply and are expressed in the cytoplasm of most vertebrate cells, including human cells. Part of the genome encoding the structural protein genes, which is amplified during a normal infection, is replaced by a transgene. Three types of vector have been developed: virus-like particles, layered DNA-RNA vectors and replication-competent vectors. Virus-like particles contain replicon RNA that is defective since it contains a cloned gene in place of the structural protein genes, and thus are able to undergo only one cycle of expression. They are produced by transfection of vector RNA, and helper RNAs encoding the structural proteins. Layered DNA-RNA vectors express the Semliki Forest virus replicon from a cDNA copy via a cytomegalovirus promoter. Replication-competent vectors contain a transgene in addition to the structural protein genes. Alphavirus vectors are used for three main applications: vaccine construction, therapy of central nervous system disease, and cancer therapy.
Current progress of polymeric gene vectors
Institute of Scientific and Technical Information of China (English)
ZENG Xuan; SUN YunXia; ZHUO RenXi; ZHANG XianZheng
2011-01-01
After over 40 years ot progress,gene therapy provides great opportunities for treating diseases from various genetic disorders,infections and cancers.The success of gene therapy largely depends on the availability of suitable gene vectors.As an attractive alternative to virus-based gene therapy,non-viral gene delivery system has been developed and investigated due to their merits including low immunogenecity,convenient operability,and large-scale manufacturability [1].Because polycations can condense with DNA as a result of electrostatic interactions,form nanosize polyplexes,and protect DNA from degradation by DNase,cationic polymer becomes a major type of non-viral gene delivery vectors (Figure 1) [2].A wide range of polymeric vectors have been developed and investigated in the past decade,such as polyethylenimine (PEI)-based vectors,poly(L-lysine) (PLL)-based vectors,dendrimer-based vectors,polypeptide-based vectors,and chitosan-based vectors [3].However,unlike viral vectors that have the ability to infect host cells and overcome cellular barriers through the course of evolution,nonviral gene vectors exhibit Significantly reduced transfection efficiency as they are obstructed by various extra- and intracellular barriers,including serum proteins in blood stream,cell membrane,endosomal compartment and nuclear membrane [4].
Vector-Resonance-Multimode Instability
Sergeyev, S. V.; Kbashi, H.; Tarasov, N.; Loiko, Yu.; Kolpakov, S. A.
2017-01-01
The modulation and multimode instabilities are the main mechanisms which drive spontaneous spatial and temporal pattern formation in a vast number of nonlinear systems ranging from biology to laser physics. Using an Er-doped fiber laser as a test bed, here for the first time we demonstrate both experimentally and theoretically a new type of a low-threshold vector-resonance-multimode instability which inherits features of multimode and modulation instabilities. The same as for the multimode instability, a large number of longitudinal modes can be excited without mode synchronization. To enable modulation instability, we modulate the state of polarization of the lasing signal with the period of the beat length by an adjustment of the in-cavity birefringence and the state of polarization of the pump wave. As a result, we show the regime's tunability from complex oscillatory to periodic with longitudinal mode synchronization in the case of resonance matching between the beat and cavity lengths. Apart from the interest in laser physics for unlocking the tunability and stability of dynamic regimes, the proposed mechanism of the vector-resonance-multimode instability can be of fundamental interest for the nonlinear dynamics of various distributed systems.
Adam, C; Sanchez-Guillen, J; Wereszczynski, A
2012-01-01
We analyze the vector meson formulation of the BPS Skyrme model in (3+1) dimensions, where the term of sixth power in first derivatives characteristic for the original, integrable BPS Skyrme model (the topological or baryon current squared) is replaced by a coupling between the vector meson $\\omega_\\mu$ and the baryon current. We find that the model remains integrable in the sense of generalized integrability and almost solvable (reducible to a set of two first order ODEs) for any value of the baryon charge. Further, we analyze the appearance of topological solitons for two one-parameter families of one vacuum potentials: the old Skyrme potentials and the so-called BPS potentials. Depending on the value of the parameters we find several qualitatively different possibilities. In the massless case we have a parameter region with no skyrmions, a unique compact skyrmion with a discontinuous first derivative at the boundary (equivalently, with a source term located at the boundary, which screens the topological ch...
Transversals of Complex Polynomial Vector Fields
DEFF Research Database (Denmark)
Dias, Kealey
by rotational constants. Transversals are a certain class of curves for such a family of vector fields that represent the bifurcation states for this family of vector fields. More specifically, transversals are curves that coincide with a homoclinic separatrix for some rotation of the vector field. Given......, an important step was proving that the transversals possessed a certain characteristic. Understanding transversals might be the key to proving other polynomial vector fields are generic, and they are important in understanding bifurcations of polynomial vector fields in general. We consider two important...... examples of rotated families to argue this. There will be discussed several open questions concerning the number of transversals that can appear for a certain degree d of a polynomial vector field, and furthermore how transversals are analyzed with respect to bifurcations around multiple equilibrium points....
A Modified Moist Ageostrophic Q Vector
Institute of Scientific and Technical Information of China (English)
YUE Caijun; SHOU Shaowen
2008-01-01
The quasi-geostrophic Q vector is an important diagnostic tool for studying development of surface rainfall associated with large-scale weather systems and is calculated using data at single vertical level. When ageostrophic Q vector was introduced, it required data at two vertical levels. In this study, moist ageostrophic Q vector is modified so that it can be calculated using data at a single vertical level. The comparison study between the original and modified moist ageostrophic Q vectors is conducted using the data from 5 to 6 July 1991 during the torrential rainfall event associated with the Changjiang-Huaihe mei-yu front in China. The results reveal that divergences of original and modified moist ageostrophic Q vectors have similar horizontal distributions and their centers are almost located in the precipitation centers. This indicates that modified moist ageostrophic Q vector can be used to diagnose convective development with reasonable accuracy.
Higgs Decays and Brane Gravi-vectors
Clark, T. E.; Liu, B. Y.; Love, S. T.; Xiong, C.; ter Veldhuis, T.
2008-01-01
Higgs boson decays in flexible brane world models with stable, massive gravi-vectors are considered. Such vectors couple bilinearly to the Standard Model fields through either the Standard Model energy-momentum tensor, the weak hypercharge field strength or the Higgs scalar. The role of the coupling involving the extrinsic curvature is highlighted. It is found that within the presently allowed parameter space, the decay rate of the Higgs into two gravi-vectors (which would appear as an invisi...
[Research progress on malaria vector control].
Zhu, Guo-Ding; Cao, Jun; Zhou, Hua-Yun; Gao, Qi
2013-06-01
Vector control plays a crucial role in the stages of malaria control and elimination. Currently, it mainly relies on the chemical control methods for adult mosquitoes in malaria endemic areas, however, it is undergoing the serious threat by insecticide resistance. In recent years, the transgenic technologies of malaria vectors have made a great progress in the laboratory. This paper reviews the challenges of the traditional methods and the rapid developed genetic modified technology in the application of vector control.
Integrated epidemiology for vector-borne zoonoses
2016-01-01
The development and application of interventions for the control of vector-borne zoonoses requires broad understanding of epidemiological linkages between vector, animal infection and human infection. However, there are significant gaps in our understanding of these linkages and a lack of appropriate data poses a considerable barrier to addressing this issue. A move towards strengthened surveillance of vectors and disease in both animal and human hosts, in combination with linked human-animal...
Construction of shRNA lentiviral vector
Directory of Open Access Journals (Sweden)
Hong Song
2010-12-01
Full Text Available Lentiviruses have been adapted as gene delivery vehicles. This article summarized shRNA lentiviral vector methods generally used in research laboratories. The main procedures of shRNA lentiviral vector include that (1 Target sequences screening and shRNA oligonucleotides designing, (2 insert designed oligonucleotides into lentiviral vectors, (3 using packaging cells to produce shRNA lentivirus, and (4 transducing target cells with shRNA lentivirus.
Genetic manipulation of endosymbionts to control vector and vector borne diseases
Directory of Open Access Journals (Sweden)
Jay Prakash Gupta
Full Text Available Vector borne diseases (VBD are on the rise because of failure of the existing methods of control of vector and vector borne diseases and the climate change. A steep rise of VBDs are due to several factors like selection of insecticide resistant vector population, drug resistant parasite population and lack of effective vaccines against the VBDs. Environmental pollution, public health hazard and insecticide resistant vector population indicate that the insecticides are no longer a sustainable control method of vector and vector-borne diseases. Amongst the various alternative control strategies, symbiont based approach utilizing endosymbionts of arthropod vectors could be explored to control the vector and vector borne diseases. The endosymbiont population of arthropod vectors could be exploited in different ways viz., as a chemotherapeutic target, vaccine target for the control of vectors. Expression of molecules with antiparasitic activity by genetically transformed symbiotic bacteria of disease-transmitting arthropods may serve as a powerful approach to control certain arthropod-borne diseases. Genetic transformation of symbiotic bacteria of the arthropod vector to alter the vector’s ability to transmit pathogen is an alternative means of blocking the transmission of VBDs. In Indian scenario, where dengue, chikungunya, malaria and filariosis are prevalent, paratransgenic based approach can be used effectively. [Vet World 2012; 5(9.000: 571-576
A New Incremental Support Vector Machine Algorithm
Directory of Open Access Journals (Sweden)
Wenjuan Zhao
2012-10-01
Full Text Available Support vector machine is a popular method in machine learning. Incremental support vector machine algorithm is ideal selection in the face of large learning data set. In this paper a new incremental support vector machine learning algorithm is proposed to improve efficiency of large scale data processing. The model of this incremental learning algorithm is similar to the standard support vector machine. The goal concept is updated by incremental learning. Each training procedure only includes new training data. The time complexity is independent of whole training set. Compared with the other incremental version, the training speed of this approach is improved and the change of hyperplane is reduced.
Pro jective vector fields on Finsler manifolds
Institute of Scientific and Technical Information of China (English)
TIAN Huang-jia
2014-01-01
In this paper, we give the equation that characterizes projective vector fields on a Finsler manifold by the local coordinate. Moreover, we obtain a feature of the projective fields on the compact Finsler manifold with non-positive flag curvature and the non-existence of projective vector fields on the compact Finsler manifold with negative flag curvature. Furthermore, we deduce some expectable, but non-trivial relationships between geometric vector fields such as projective, affine, conformal, homothetic and Killing vector fields on a Finsler manifold.
Vector perturbations of galaxy number counts
Durrer, Ruth; Tansella, Vittorio
2016-07-01
We derive the contribution to relativistic galaxy number count fluctuations from vector and tensor perturbations within linear perturbation theory. Our result is consistent with the the relativistic corrections to number counts due to scalar perturbation, where the Bardeen potentials are replaced with line-of-sight projection of vector and tensor quantities. Since vector and tensor perturbations do not lead to density fluctuations the standard density term in the number counts is absent. We apply our results to vector perturbations which are induced from scalar perturbations at second order and give numerical estimates of their contributions to the power spectrum of relativistic galaxy number counts.
Vector perturbations of galaxy number counts
Durrer, Ruth
2016-01-01
We derive the contribution to relativistic galaxy number count fluctuations from vector and tensor perturbations within linear perturbation theory. Our result is consistent with the the relativistic corrections to number counts due to scalar perturbation, where the Bardeen potentials are replaced with line-of-sight projection of vector and tensor quantities. Since vector and tensor perturbations do not lead to density fluctuations the standard density term in the number counts is absent. We apply our results to vector perturbations which are induced from scalar perturbations at second order and give numerical estimates of their contributions to the power spectrum of relativistic galaxy number counts.
Synthetic Aperture Vector Flow Imaging
DEFF Research Database (Denmark)
Villagómez Hoyos, Carlos Armando
The main objective of this project was to continue the development of a synthetic aperture vector flow estimator. This type of estimator is capable of overcoming two of the major limitations in conventional ultrasound systems: 1) the inability to scan large region of interest with high temporal...... resolutions; 2) the lack of capability in detecting flow other than the one along the direction of the beam. Addressing these technical limitations would translate in the clinic as a gain in valuable clinical information and a removal of operator-dependant sources of error, which would improve the diagnosis....... The main contribution of this work was the development of an angle estimator which features high accuracy and low standard deviation over the full 360◦ range. The estimator demonstrated its capability of operating at high frame rates (> 1000 Hz), and simultaneously detecting a large range of flow...
Directory of Open Access Journals (Sweden)
Chuan-Ren Chen
2015-02-01
Full Text Available Even though the sensitivity of direct dark matter search experiments reaches the level of about 10−45 cm2, no confident signal of dark matter has been observed. We point out that, if dark matter is a vector boson, the null result in direct dark matter search experiments may be due to the destructive effects in dark-matter–nucleon elastic scattering. We illustrate the scenario using a modified Higgs portal model that includes exotic quarks. The significant cancellation can occur for a certain mass gap between new heavy quark and dark matter. As a result, the spin-independent dark-matter–nucleon elastic scattering is so suppressed that the future direct search experiments will hardly observe the signal of dark matter.
Differentially Private Support Vector Machines
Sarwate, Anand; Monteleoni, Claire
2009-01-01
This paper addresses the problem of practical privacy-preserving machine learning: how to detect patterns in massive, real-world databases of sensitive personal information, while maintaining the privacy of individuals. Chaudhuri and Monteleoni (2008) recently provided privacy-preserving techniques for learning linear separators via regularized logistic regression. With the goal of handling large databases that may not be linearly separable, we provide privacy-preserving support vector machine algorithms. We address general challenges left open by past work, such as how to release a kernel classifier without releasing any of the training data, and how to tune algorithm parameters in a privacy-preserving manner. We provide general, efficient algorithms for linear and nonlinear kernel SVMs, which guarantee $\\epsilon$-differential privacy, a very strong privacy definition due to Dwork et al. (2006). We also provide learning generalization guarantees. Empirical evaluations reveal promising performance on real and...
Haydar, Deniz; Wolff, Wim J.
2011-01-01
Oyster transports are among the leading anthropogenic vectors of coastwise introduction of non-indigenous species. Using the oyster industry of the Netherlands as a model system, we investigated the relationship between vector strength (number of invasions) and vector tempo (magnitude and frequency
Clustering Categories in Support Vector Machines
DEFF Research Database (Denmark)
Carrizosa, Emilio; Nogales-Gómez, Amaya; Morales, Dolores Romero
2017-01-01
The support vector machine (SVM) is a state-of-the-art method in supervised classification. In this paper the Cluster Support Vector Machine (CLSVM) methodology is proposed with the aim to increase the sparsity of the SVM classifier in the presence of categorical features, leading to a gain...
Vector-Quantization using Information Theoretic Concepts
DEFF Research Database (Denmark)
Lehn-Schiøler, Tue; Hegde, Anant; Erdogmus, Deniz
2005-01-01
The process of representing a large data set with a smaller number of vectors in the best possible way, also known as vector quantization, has been intensively studied in the recent years. Very efficient algorithms like the Kohonen Self Organizing Map (SOM) and the Linde Buzo Gray (LBG) algorithm...
Clifford Fourier transform on vector fields.
Ebling, Julia; Scheuermann, Gerik
2005-01-01
Image processing and computer vision have robust methods for feature extraction and the computation of derivatives of scalar fields. Furthermore, interpolation and the effects of applying a filter can be analyzed in detail and can be advantages when applying these methods to vector fields to obtain a solid theoretical basis for feature extraction. We recently introduced the Clifford convolution, which is an extension of the classical convolution on scalar fields and provides a unified notation for the convolution of scalar and vector fields. It has attractive geometric properties that allow pattern matching on vector fields. In image processing, the convolution and the Fourier transform operators are closely related by the convolution theorem and, in this paper, we extend the Fourier transform to include general elements of Clifford Algebra, called multivectors, including scalars and vectors. The resulting convolution and derivative theorems are extensions of those for convolution and the Fourier transform on scalar fields. The Clifford Fourier transform allows a frequency analysis of vector fields and the behavior of vector-valued filters. In frequency space, vectors are transformed into general multivectors of the Clifford Algebra. Many basic vector-valued patterns, such as source, sink, saddle points, and potential vortices, can be described by a few multivectors in frequency space.
Application of Vectors to Relative Velocity
Tin-Lam, Toh
2004-01-01
The topic 'relative velocity' has recently been introduced into the Cambridge Ordinary Level Additional Mathematics syllabus under the application of Vectors. In this note, the results of relative velocity and the 'reduction to rest' technique of teaching relative velocity are derived mathematically from vector algebra, in the hope of providing…
Articulated Multimedia Physics, Lesson 4, Vectors.
New York Inst. of Tech., Old Westbury.
As the fourth lesson of the Articulated Multimedia Physics Course, instructional materials are presented in this study guide. The subject matter is concerned with displacements, speeds, scalers, vector sum, and vector analysis.The content is arranged in scrambled form, and the use of matrix transparencies is required for students to control their…
Diffeomorphism Invariant Theories and Vector Supersymmetry
Piguet, O
2000-01-01
Einstein gravity in the Palatini first order formalism is shown to possess a vector supersymmetry of the type encountered in the topological gauge theories. A peculiar feature of the gravitationel theory is the link of this vector supersymmetry with the field equation of motion of the Faddeev-Popov ghost associated to diffeomorphism invariance.
Deep Support Vector Machines for Regression Problems
Wiering, Marco; Schutten, Marten; Millea, Adrian; Meijster, Arnold; Schomaker, Lambertus
2013-01-01
In this paper we describe a novel extension of the support vector machine, called the deep support vector machine (DSVM). The original SVM has a single layer with kernel functions and is therefore a shallow model. The DSVM can use an arbitrary number of layers, in which lower-level layers contain su
Increasing the Efficacy of Oncolytic Adenovirus Vectors
Directory of Open Access Journals (Sweden)
William S. M. Wold
2010-08-01
Full Text Available Oncolytic adenovirus (Ad vectors present a new modality to treat cancer. These vectors attack tumors via replicating in and killing cancer cells. Upon completion of the vector replication cycle, the infected tumor cell lyses and releases progeny virions that are capable of infecting neighboring tumor cells. Repeated cycles of vector replication and cell lysis can destroy the tumor. Numerous Ad vectors have been generated and tested, some of them reaching human clinical trials. In 2005, the first oncolytic Ad was approved for the treatment of head-and-neck cancer by the Chinese FDA. Oncolytic Ads have been proven to be safe, with no serious adverse effects reported even when high doses of the vector were injected intravenously. The vectors demonstrated modest anti-tumor effect when applied as a single agent; their efficacy improved when they were combined with another modality. The efficacy of oncolytic Ads can be improved using various approaches, including vector design, delivery techniques, and ancillary treatment, which will be discussed in this review.
Nonlinear dynamics of a vectored thrust aircraft
DEFF Research Database (Denmark)
Sørensen, C.B; Mosekilde, Erik
1996-01-01
With realistic relations for the aerodynamic coefficients, numerical simulations are applied to study the longitudional dynamics of a thrust vectored aircraft. As function of the thrust magnitude and the thrust vectoring angle the equilibrium state exhibits two saddle-node bifurcations and three ...
Chiral Corrections to Vector Meson Decay Constants
Bijnens, J; Talavera, P; Bijnens, Johan; Gosdzinsky, Peter; Talavera, Pere
1998-01-01
We calculate the leading quark mass corrections of order $m_q\\log(m_q)$, $m_q$ and $m_q^{3/2}$ to the vector meson decay constants within Heavy Vector Meson Chiral Perturbation Theory. We discuss the issue of electromagnetic gauge invariance and the heavy mass expansion. Reasonably good fits to the observed decay constants are obtained.
CLASSIFICATION OF CUBIC PARAMETERIZED HOMOGENEOUS VECTOR FIELDS
Institute of Scientific and Technical Information of China (English)
Karnal H.Yasir; TANG Yun
2002-01-01
In this paper the cubic homogeneous parameterized vector fields are studied.The classification of the phase portrait near the critical point is presented. This classification is an extension of the result given by Takens to the cubic homogeneous parameterized vector fields with six parameters.
CLASSIFICATION OF CUBIC PARAMETERIZED HOMOGENEOUS VECTOR FIELDS
Institute of Scientific and Technical Information of China (English)
KamalH.Yasir; TNAGYun
2002-01-01
In this paper the cubic homogeneous parameterized vector fields are studied.The classification of the phase portrait near the critical point is presented.This classification is an extension of the result given by takens to the cubic homogeneous parameterized vector fields with six parameters.
2010-07-01
... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Vectors. 240.206 Section 240.206 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.206 Vectors....
Vector Spaces of Non-measurable Functions
Institute of Scientific and Technical Information of China (English)
Francisco J. GARC(I)A-PACHECO; Juan B. SEOANE-SEP(U)LVEDA
2006-01-01
We show that there exists an infinite dimensional vector space every non-zero element of which is a non-measurable function. Moreover, this vector space can be chosen to be closed and to have dimensionβ for any cardinalityβ. Some techniques involving measure theory and density characters of Banach spaces are used.
A Survey on Distance Vector Routing Protocols
Tang, Linpeng
2011-01-01
In this paper we give a brief introduction to five different distance vector routing protocols (RIP, AODV, EIGRP, RIP-MTI and Babel) and give some of our thoughts on how to solve the count to infinity problem. Our focus is how distance vector routing protocols, based on limited information, can prevent routing loops and the count to infinity problem.
Cascade Support Vector Machines with Dimensionality Reduction
Directory of Open Access Journals (Sweden)
Oliver Kramer
2015-01-01
Full Text Available Cascade support vector machines have been introduced as extension of classic support vector machines that allow a fast training on large data sets. In this work, we combine cascade support vector machines with dimensionality reduction based preprocessing. The cascade principle allows fast learning based on the division of the training set into subsets and the union of cascade learning results based on support vectors in each cascade level. The combination with dimensionality reduction as preprocessing results in a significant speedup, often without loss of classifier accuracies, while considering the high-dimensional pendants of the low-dimensional support vectors in each new cascade level. We analyze and compare various instantiations of dimensionality reduction preprocessing and cascade SVMs with principal component analysis, locally linear embedding, and isometric mapping. The experimental analysis on various artificial and real-world benchmark problems includes various cascade specific parameters like intermediate training set sizes and dimensionalities.
Alphavirus vectors for cancer gene therapy (review).
Yamanaka, Ryuya
2004-04-01
Alphaviruses have several characteristics that make them attractive as gene therapy vectors such as transient and high-level expression of a heterologous gene. Alphavirus vectors, Semliki Forest virus (SFV), Sindbis virus (SIN) and Venezuelan equine encephalitis virus (VEE) have been developed as gene expression vectors. Alphaviruses are positive-strand RNA viruses that can mediate efficient cytoplasmic gene expression in mammalian cells. The alphavirus RNA replication machinery has been engineered for high level heterologous gene expression. Since an RNA virus vector cannot integrate into chromosomal DNA, concerns about cell transformation are reduced. Alphavirus vectors demonstrate promise for the safe tumor-killing and tumor-specific immune responses. Recombinant alphavirus RNA replicons may facilitate gene therapy of cancer.
Vector Diffusion Maps and the Connection Laplacian
Singer, Amit
2011-01-01
We introduce {\\em vector diffusion maps} (VDM), a new mathematical framework for organizing and analyzing massive high dimensional data sets, images and shapes. VDM is a mathematical and algorithmic generalization of diffusion maps and other non-linear dimensionality reduction methods, such as LLE, ISOMAP and Laplacian eigenmaps. While existing methods are either directly or indirectly related to the heat kernel for functions over the data, VDM is based on the heat kernel for vector fields. VDM provides tools for organizing complex data sets, embedding them in a low dimensional space, and interpolating and regressing vector fields over the data. In particular, it equips the data with a metric, which we refer to as the {\\em vector diffusion distance}. In the manifold learning setup, where the data set is distributed on (or near) a low dimensional manifold $\\MM^d$ embedded in $\\RR^{p}$, we prove the relation between VDM and the connection-Laplacian operator for vector fields over the manifold.
Axial Vector $Z'$ and Anomaly Cancellation
Ismail, Ahmed; Tsao, Kuo-Hsing; Unwin, James
2016-01-01
Whilst the prospect of new $Z'$ gauge bosons with only axial couplings to the Standard Model (SM) fermions is widely discussed, examples of anomaly-free renormalisable models are lacking in the literature. We look to remedy this by constructing several motivated examples. Specifically, we consider axial vectors which couple universally to all SM fermions, as well as those which are generation-specific, leptophilic, and leptophobic. Anomaly cancellation typically requires the presence of new coloured and charged chiral fermions, and we argue that the masses of these new states must generally be comparable to that of the axial vector. Finally, an axial vector mediator could provide a portal between SM and hidden sector states, and we also consider the possibility that the axial vector couples to dark matter. If the dark matter relic density is set due to freeze-out via the axial vector, this strongly constrains the parameter space.
Low-amplitude vector screening solitons
Institute of Scientific and Technical Information of China (English)
Keqing Lu(卢克清); Xiangping Zhu(朱香平); Wei Zhao(赵卫); Yanlong Yang(杨延龙); Jinping Li(李金萍); Yanpeng Zhang(张彦鹏); Junchang Zhang(张君昌)
2004-01-01
We show self-coupled and cross-coupled vector beam evolution equations in the low-amplitude regime for screening solitons,which can exhibit the analytical solutions of bright-bright and dark-dark vector solitons.Our analysis indicates that these self-coupled vector solitons are obtained irrespective of the intensities of the two optical beams,whereas these cross-coupled vector solitons can be established when the intensities of the two optical beams are equal.Relevant examples are provided where the photorefractive crystal is lithium niobate(LiNbO3).The stability properties of these vector solitons have been investigated numerically and it has been found that they are stable.
Gauge vectors and double beta decay
Fonseca, Renato M.; Hirsch, Martin
2017-02-01
We discuss contributions to neutrinoless double beta (0 ν β β ) decay involving vector bosons. The starting point is a list of all possible vector representations that may contribute to 0 ν β β decay via d =9 or d =11 operators at tree level. We then identify gauge groups which contain these vectors in the adjoint representation. Even though the complete list of vector fields that can contribute to 0 ν β β up to d =11 is large (a total of 46 vectors), only a few of them can be gauge bosons of phenomenologically realistic groups. These latter cases are discussed in some more detail, and lower (upper) limits on gauge boson masses (mixing angles) are derived from the absence of 0 ν β β decay.
Geoacoustic inversion using the vector field
Crocker, Steven E.
The main goal of this project was to study the use of the acoustic vector field, separately or in combination with the scalar field, to estimate the depth dependent geoacoustic properties of the seafloor via non-linear inversion. The study was performed in the context of the Sediment Acoustics Experiment 2004 (SAX04) conducted in the Northern Gulf of Mexico (GOM) where a small number of acoustic vector sensors were deployed in close proximity to the seafloor. A variety of acoustic waveforms were transmitted into the seafloor at normal incidence. The acoustic vector sensors were located both above and beneath the seafloor interface where they measured the acoustic pressure and the acoustic particle acceleration. Motion data provided by the buried vector sensors were affected by a suspension response that was sensitive to the mass properties of the sensor, the sediment density and sediment elasticity (e.g., shear wave speed). The suspension response for the buried vector sensors included a resonance within the analysis band of 0.4 to 2.0 kHz. The suspension resonance represented an unknown complex transfer function between the acoustic vector field in the seabed and data representing that field. Therefore, inverse methods developed for this study were required to 1) estimate dynamic properties of the sensor suspension resonance and 2) account for the associated corruption of vector field data. A method to account for the vector sensor suspense response function was integrated directly into the inversion methods such that vector channel data corruption was reduced and an estimate of the shear wave speed in the sediment was returned. Inversions of real and synthetic data sets indicated that information about sediment shear wave speed was carried by the suspension response of the buried sensors, as opposed to being contained inherently within the acoustic vector field.
Image Coding Based on Address Vector Quantization.
Feng, Yushu
Image coding is finding increased application in teleconferencing, archiving, and remote sensing. This thesis investigates the potential of Vector Quantization (VQ), a relatively new source coding technique, for compression of monochromatic and color images. Extensions of the Vector Quantization technique to the Address Vector Quantization method have been investigated. In Vector Quantization, the image data to be encoded are first processed to yield a set of vectors. A codeword from the codebook which best matches the input image vector is then selected. Compression is achieved by replacing the image vector with the index of the code-word which produced the best match, the index is sent to the channel. Reconstruction of the image is done by using a table lookup technique, where the label is simply used as an address for a table containing the representative vectors. A code-book of representative vectors (codewords) is generated using an iterative clustering algorithm such as K-means, or the generalized Lloyd algorithm. A review of different Vector Quantization techniques are given in chapter 1. Chapter 2 gives an overview of codebook design methods including the Kohonen neural network to design codebook. During the encoding process, the correlation of the address is considered and Address Vector Quantization is developed for color image and monochrome image coding. Address VQ which includes static and dynamic processes is introduced in chapter 3. In order to overcome the problems in Hierarchical VQ, Multi-layer Address Vector Quantization is proposed in chapter 4. This approach gives the same performance as that of the normal VQ scheme but the bit rate is about 1/2 to 1/3 as that of the normal VQ method. In chapter 5, a Dynamic Finite State VQ based on a probability transition matrix to select the best subcodebook to encode the image is developed. In chapter 6, a new adaptive vector quantization scheme, suitable for color video coding, called "A Self -Organizing
The Representation of a Broadband Vector Field
Institute of Scientific and Technical Information of China (English)
Qunyan Ren; Jean Pierre Hermand; Shengchun Piao
2011-01-01
Compared to a scalar pressure sensor,a vector sensor can provide a higher signal-to-noise ratio (SNR)signal and more detailed information on the sound field.Study on vector sensors and their applications have become a hot topic.Research on the representation of a vector field is highly relevant for extending the scope of vector sensor technology.This paper discusses the range-frequency distribution of the vector field due to a broadband acoustic source moving in a shallow-water waveguide as the self noise of a surface ship,and the vector extension of the waveguide impulse response measured over a limited frequency range using an active source of known waveform.From theory analysis and numerical simulation,the range-frequency representation of a vector field exhibits an interference structure qualitatively similar to that of the corresponding pressure field but,being quantitatively different,provides additional information on the waveguide,especially through the vertical component.For the range-frequency representation,physical quantities that can better exhibit the interference characteristics of the waveguide are the products of pressure and particle velocity and of the pressure and pressure gradient.An image processing method to effectively detect and isolate the individual striations from an interference structure was reviewed briefly.The representation of the vector impulse response was discussed according to two different measurement systems,also known as particle velocity and pressure gradient.The vector impulse response representation can not only provide additional information from pressure only but even more than that of the range-frequency representation.
Efficient than a Nonlentiviral Vector
Directory of Open Access Journals (Sweden)
Tao Yang
2010-01-01
Full Text Available Background. Lentiviral constructs reportedly can integrate into the genome of non-dividing, terminally differentiated cells and dividing cells, for long-term gene expression. This investigation tested whether a third generation lentiviral-mediated small interfering RNA (siRNA delivered into renal epithelial and fibroblast cells against type II transforming growth factor-beta receptor (siRNA-TBRII could better attenuate renal fibrogenesis in comparison with a non-lentiviral construct. Methods. HIV-derived lentiviral and non-lentiviral constructs were used to transfect cells with siRNA-TBRII or siRNA-EGFP control. Human embryonic kidney (HEK-293T, renal epithelial cells (NRK-52E and renal fibroblasts (NRK-49F were transfected and gene silencing quantified (fluorescence microscopy, Western blotting, fluorescence-activated cell sorting. Renal fibrogenesis was assessed using extracellular matrix protein synthesis (fibronectin and collagen-III; Western immunoblot, and α-smooth muscle actin (α-SMA was analysed as a marker of fibroblast activation and epithelial-to-mesenchymal transdifferentiation (EMT. Results. Lentiviral-mediated siRNA-TBRII significantly suppressed TBRII expression in all cell lines, and also significantly suppressed renal fibrogenesis. In comparison with the non-lentiviral construct, lentiviral-mediated siRNA-TBRII produced stronger and more persistent inhibition of collagen-III in NRK-49F cells, fibronectin in all renal cell lines, and α-SMA in renal epithelial cells. Conclusions. Lentiviral vector systems against TBRII can be delivered into renal cells to efficiently limit renal fibrogenesis by sequence-specific gene silencing.
New Anomaly of the Axial-Vector Current
Institute of Scientific and Technical Information of China (English)
HE Han-Xin
2001-01-01
By computing the axial-vector current operator equation, we find the anomalous axial-vector curl equation besides the well-known anomalous axial-vector divergence equation (the Adler-Bell-Jackiw anomaly) and discuss its implication.``
A NEW HYPERSPHERE SUPPORT VECTOR MACHINE ALGORITHM
Institute of Scientific and Technical Information of China (English)
Zhang Xinfeng; Shen Lansun
2006-01-01
The hypersphere support vector machine is a new algorithm in pattern recognition. By studying three kinds ofhypersphere support vector machines, it is found that their solutions are identical and the margin between two classes of samples is zero or is not unique. In this letter, a new kind ofhypersphere support vector machine is proposed. By introducing a parameter n(n＞l), a unique solution of the margin can be obtained.Theoretical analysis and experimental results show that the proposed algorithm can achieve better generalization performance.
Nonlinear singular vectors and nonlinear singular values
Institute of Scientific and Technical Information of China (English)
无
2000-01-01
A novel concept of nonlinear singular vector and nonlinear singular value is introduced, which is a natural generalization of the classical linear singular vector and linear singular value to the nonlinear category. The optimization problem related to the determination of nonlinear singular vectors and singular values is formulated. The general idea of this approach is demonstrated by a simple two-dimensional quasigeostrophic model in the atmospheric and oceanic sciences. The advantage and its applications of the new method to the predictability, ensemble forecast and finite-time nonlinear instability are discussed. This paper makes a necessary preparation for further theoretical and numerical investigations.
Robust Pseudo-Hierarchical Support Vector Clustering
DEFF Research Database (Denmark)
Hansen, Michael Sass; Sjöstrand, Karl; Olafsdóttir, Hildur
2007-01-01
Support vector clustering (SVC) has proven an efficient algorithm for clustering of noisy and high-dimensional data sets, with applications within many fields of research. An inherent problem, however, has been setting the parameters of the SVC algorithm. Using the recent emergence of a method...... for calculating the entire regularization path of the support vector domain description, we propose a fast method for robust pseudo-hierarchical support vector clustering (HSVC). The method is demonstrated to work well on generated data, as well as for detecting ischemic segments from multidimensional myocardial...
Meromorphic Vector Fields and Circle Packings
DEFF Research Database (Denmark)
Dias, Kealey
of dynamical systems, continuous and discrete, correspond to the study of differential equations (vector fields) and iteration of mappings respectively. In holomorphic dynamics, the systems studied are restricted to those described by holomorphic (complex analytic) functions or meromorphic (allowing poles...... as singularities) functions. There already exists a well-developed theory for iterative holomorphic dynamical systems, and successful relations found between iteration theory and flows of vector fields have been one of the main motivations for the recent interest in holomorphic vector fields. Restricting...
600-GHz Electronically Tunable Vector Measurement System
Dengler, Robert; Maiwald, Frank; Siegel, Peter
2007-01-01
A compact, high-dynamic-range, electronically tunable vector measurement system that operates in the frequency range from approximately 560 to approximately 635 GHz has been developed as a prototype of vector measurement systems that would be suitable for use in nearly-real-time active submillimeter-wave imaging. As used here, 'vector measurement system" signifies an instrumentation system that applies a radio-frequency (RF) excitation to an object of interest and measures the resulting amplitude and phase response, relative to either the applied excitatory signal or another reference signal related in a known way to applied excitatory signal.
Neural net approach to predictive vector quantization
Mohsenian, Nader; Nasrabadi, Nasser M.
1992-11-01
A new predictive vector quantization (PVQ) technique, capable of exploring the nonlinear dependencies in addition to the linear dependencies that exist between adjacent blocks of pixels, is introduced. Two different classes of neural nets form the components of the PVQ scheme. A multi-layer perceptron is embedded in the predictive component of the compression system. This neural network, using the non-linearity condition associated with its processing units, can perform as a non-linear vector predictor. The second component of the PVQ scheme vector quantizes (VQ) the residual vector that is formed by subtracting the output of the perceptron from the original wave-pattern. Kohonen Self-Organizing Feature Map (KSOFM) was utilized as a neural network clustering algorithm to design the codebook for the VQ technique. Coding results are presented for monochrome 'still' images.
Twisted Vector Bundles on Pointed Nodal Curves
Indian Academy of Sciences (India)
Ivan Kausz
2005-05-01
Motivated by the quest for a good compactification of the moduli space of -bundles on a nodal curve we establish a striking relationship between Abramovich’s and Vistoli’s twisted bundles and Gieseker vector bundles.
Sensorless vector and direct torque control
Vas, Peter
1998-01-01
This is the first comprehensive book on sensorless high performance a.c. drives. It is essential reading for anyone interested in acquiring a solid background on sensorless torque-controlled drives. It presents a detailed and unified treatment of sensorless vector-controlled and direct-torque controlled drive systems. It also discusses the applications of artificial intelligence to drives. Where possible, space vector theory is used and emphasis is laid on detailed mathematical and physical analysis. Sensorless drive schemes for different types of permanent magnet synchronous motors, synchronous reluctance motors, and induction motors are also presented. These include more than twenty vector drives e.g. five types of MRAS-based vector drives, and eleven types of direct-torque-controlled (DTC) drives, e.g. the ABB DTC drive. However, torque-controlled switched reluctance motor drives are also discussed due to their emerging importance. The book also covers various drive applications using artificial intellige...
Vector Potential Generation for Numerical Relativity Simulations
Silberman, Zachary; Faber, Joshua; Adams, Thomas; Etienne, Zachariah; Ruchlin, Ian
2017-01-01
Many different numerical codes are employed in studies of highly relativistic magnetized accretion flows around black holes. Based on the formalisms each uses, some codes evolve the magnetic field vector B, while others evolve the magnetic vector potential A, the two being related by the curl: B=curl(A). Here, we discuss how to generate vector potentials corresponding to specified magnetic fields on staggered grids, a surprisingly difficult task on finite cubic domains. The code we have developed solves this problem in two ways: a brute-force method, whose scaling is nearly linear in the number of grid cells, and a direct linear algebra approach. We discuss the success both algorithms have in generating smooth vector potential configurations and how both may be extended to more complicated cases involving multiple mesh-refinement levels. NSF ACI-1550436
Integrated epidemiology for vector-borne zoonoses.
Wardrop, Nicola A
2016-02-01
The development and application of interventions for the control of vector-borne zoonoses requires broad understanding of epidemiological linkages between vector, animal infection and human infection. However, there are significant gaps in our understanding of these linkages and a lack of appropriate data poses a considerable barrier to addressing this issue. A move towards strengthened surveillance of vectors and disease in both animal and human hosts, in combination with linked human-animal surveys, could form the backbone for epidemiological integration, enabling explicit assessment of the animal-human (and vector) interface, and subsequent implications for spill-over to human populations. Currently available data on the spatial distribution of human African trypanosomiasis allow an illustrative example.
Triangle Lattice Green Functions for Vector Fields
Moritz, Brian; Schwalm, William
2000-03-01
The triangle lattice is convenient for modeling fields and fluid flows in two dimensions. Discrete vector field equations are defined through the analogy between differential forms and simplicial homology theory. The basic vector difference operators on the lattice correspond to the graph adjacency matricies of the triangle, honeycomb, and Kagomé lattices. The scalar Green functions for nearest neighbor interactions on the triangle lattice are known in closed form in terms of the complete elliptic integrals. Green functions for vector field operators are obtained explicitly in terms of the known scalar Green functions. The scalar Green functions for the Kagomé lattice are thus written in terms of the Green functions for the triangle lattice and ultimately in closed form. Thus, Green functions for a wide range of vector difference models are reduced to closed form in terms of the complete elliptic integrals.
Low Power, Self Calibrated Vector Magnetometer Project
National Aeronautics and Space Administration — This Phase I SBIR project investigates a novel approach to vector magnetometry based on high precision measurements of the total magnetic field. The calibration is...
Small automorphic representations and degenerate Whittaker vectors
Gustafsson, Henrik P A; Persson, Daniel
2014-01-01
We investigate Fourier coefficients of automorphic forms on split simply-laced Lie groups G. We show that for automorphic representations of small Gelfand-Kirillov dimension the Fourier coefficients are completely determined by certain degenerate Whittaker vectors on G. Although we expect our results to hold for arbitrary simply-laced groups, we give complete proofs only for G=SL(3) and G=SL(4). This is based on a method of Ginzburg that associates Fourier coefficients of automorphic forms with nilpotent orbits of G. Our results complement and extend recent results of Miller and Sahi. We also use our formalism to calculate various local (real and p-adic) spherical vectors of minimal representations of the exceptional groups E_6, E_7, E_8 using global (adelic) degenerate Whittaker vectors, correctly reproducing existing results for such spherical vectors obtained by very different methods.
Insects as vectors: systematics and biology.
Rodhain, F
2015-04-01
Among the many complex relationships between insects and microorganisms such as viruses, bacteria and parasites, some have resulted in the establishment of biological systems within which the insects act as a biological vector for infectious agents. It is therefore advisable to understand the identity and biology of these vectors in depth, in order to define procedures for epidemiological surveillance and anti-vector control. The following are successively reviewed in this article: Anoplura (lice), Siphonaptera (fleas), Heteroptera (bugs: Cimicidae, Triatoma, Belostomatidae), Psychodidae (sandflies), Simuliidae (black flies), Ceratopogonidae (biting midges), Culicidae (mosquitoes), Tabanidae (horseflies) and Muscidae (tsetse flies, stable flies and pupipara). The authors provide a rapid overview of the morphology, systematics, development cycle and bio-ecology of each of these groups of vectors. Finally, their medical and veterinary importance is briefly reviewed.
Gamow vectors explain the shock profile.
Braidotti, Maria Chiara; Gentilini, Silvia; Conti, Claudio
2016-09-19
The description of shock waves beyond the shock point is a challenge in nonlinear physics and optics. Finding solutions to the global dynamics of dispersive shock waves is not always possible due to the lack of integrability. Here we propose a new method based on the eigenstates (Gamow vectors) of a reversed harmonic oscillator in a rigged Hilbert space. These vectors allow analytical formulation for the development of undular bores of shock waves in a nonlinear nonlocal medium. Experiments by a photothermal induced nonlinearity confirm theoretical predictions: the undulation period as a function of power and the characteristic quantized decays of Gamow vectors. Our results demonstrate that Gamow vectors are a novel and effective paradigm for describing extreme nonlinear phenomena.
Gamow Vectors Explain the Shock "Batman" Profile
Braidotti, Maria Chiara; Conti, Claudio
2016-01-01
The description of shock waves beyond the shock point is a challenge in nonlinear physics. Finding solutions to the global dynamics of dispersive shock waves is not always possible due to the lack of integrability. Here we propose a new method based on the eigenstates (Gamow vectors) of a reversed harmonic oscillator in a rigged Hilbert space. These vectors allow analytical formulation for the development of undular bores of shock waves in a nonlinear nonlocal medium. Experiments by a photothermal induced nonlinearity confirm theoretical predictions: as the undulation period as a function of power and the characteristic quantized decays of Gamow vectors. Our results demonstrate that Gamow vector are a novel and effective paradigm for describing extreme nonlinear phenomena.
Weaving knotted vector fields with tunable helicity
Kedia, Hridesh; Dennis, Mark R; Irvine, William T M
2016-01-01
We present a general construction of divergence-free knotted vector fields from complex scalar fields, whose closed field lines encode many kinds of knots and links, including torus knots, their cables, the figure-8 knot and its generalizations. As finite-energy physical fields they represent initial states for fields such as the magnetic field in a plasma, or the vorticity field in a fluid. We give a systematic procedure for calculating the vector potential, starting from complex scalar functions with knotted zero filaments, thus enabling an explicit computation of the helicity of these knotted fields. The construction can be used to generate isolated knotted flux tubes, filled by knots encoded in the lines of the vector field. Lastly we give examples of manifestly knotted vector fields with vanishing helicity. Our results provide building blocks for analytical models and simulations alike.
Generalized Stokes vector for three photon process
Shaji, Chitra; Satyanarayana, SVM; Sharan, Alok
2015-01-01
Stokes Muller formalism is important to understand the optical properties of materials by measuring the change in the polarization state of light upon scattering. The formalism can be extended to nonlinear scattering processes involving two and three photon processes. In this work, we derive a triple Stokes vector analytically using operator approach used in quantum theory of light. A three photon polarization state can be described by Stokes vector that has sixteen components involving cubes of intensities. The response of a material for the scattering of light in a three photon process is described by 4 x 16 Muller matrix. Polarization in Polarization out (PIPO) experiments can be carried out to determine the elements of Muller matrix. For that we identify 16 independent points in Poincare sphere and construct triple Stokes vector for each point. Four measurements to find the linear Stokes vector of the scattered light for incident light in each of the sixteen three photon states determine the Muller matrix...
The light filament as vector solitary wave
Kovachev, Lubomir M
2015-01-01
We present an analytical approach to the theory of nonlinear propagation of femtosecond optical pulses with broad-band spectrum in gases. The vector character of the nonlinear third-order polarization is investigated in details, taking into account the carrier to envelope phase. The corresponding system of vector amplitude equations is written by using left-hand and right-hand circular components of the electrical field. We found that this system nonlinear equations admits $3D+1$ vector soliton solution with Lorentz shape. The solution presents relatively stable propagation and rotation with GHz frequency of the vector of the electrical field in plane, orthogonal to the direction of propagation. The evolution of the intensity profile demonstrate weak self-compression and week spherical wave in the first milliseconds of propagation.
Ontology for vector surveillance and management.
Lozano-Fuentes, Saul; Bandyopadhyay, Aritra; Cowell, Lindsay G; Goldfain, Albert; Eisen, Lars
2013-01-01
Ontologies, which are made up by standardized and defined controlled vocabulary terms and their interrelationships, are comprehensive and readily searchable repositories for knowledge in a given domain. The Open Biomedical Ontologies (OBO) Foundry was initiated in 2001 with the aims of becoming an "umbrella" for life-science ontologies and promoting the use of ontology development best practices. A software application (OBO-Edit; *.obo file format) was developed to facilitate ontology development and editing. The OBO Foundry now comprises over 100 ontologies and candidate ontologies, including the NCBI organismal classification ontology (NCBITaxon), the Mosquito Insecticide Resistance Ontology (MIRO), the Infectious Disease Ontology (IDO), the IDOMAL malaria ontology, and ontologies for mosquito gross anatomy and tick gross anatomy. We previously developed a disease data management system for dengue and malaria control programs, which incorporated a set of information trees built upon ontological principles, including a "term tree" to promote the use of standardized terms. In the course of doing so, we realized that there were substantial gaps in existing ontologies with regards to concepts, processes, and, especially, physical entities (e.g., vector species, pathogen species, and vector surveillance and management equipment) in the domain of surveillance and management of vectors and vector-borne pathogens. We therefore produced an ontology for vector surveillance and management, focusing on arthropod vectors and vector-borne pathogens with relevance to humans or domestic animals, and with special emphasis on content to support operational activities through inclusion in databases, data management systems, or decision support systems. The Vector Surveillance and Management Ontology (VSMO) includes >2,200 unique terms, of which the vast majority (>80%) were newly generated during the development of this ontology. One core feature of the VSMO is the linkage, through
New approach to training support vector machine
Institute of Scientific and Technical Information of China (English)
Tang Faming; Chen Mianyun; Wang Zhongdong
2006-01-01
Support vector machine has become an increasingly popular tool for machine learning tasks involving classification, regression or novelty detection. Training a support vector machine requires the solution of a very large quadratic programming problem. Traditional optimization methods cannot be directly applied due to memory restrictions. Up to now, several approaches exist for circumventing the above shortcomings and work well. Another learning algorithm, particle swarm optimization, for training SVM is introduted. The method is tested on UCI datasets.
Visualization of Vector Field by Virtual Reality
Kageyama, A.; Tamura, Y.; Sato, T.
A visualization software program is developed in order to analyze three dimensional vector fields by means of today's advanced virtual reality technology. This program enables simulation researchers to interactively visualize stream lines, tracer particle motions, isosurfaces, etc.~with stereo view. The program accepts any kind of vector fields on structured mesh as an input data. A virtual reality hardware system, on which the program operates, and details of the program are described.
Killing vector fields and harmonic superfield theories
Energy Technology Data Exchange (ETDEWEB)
Groeger, Josua, E-mail: groegerj@mathematik.hu-berlin.de [Humboldt-Universität zu Berlin, Institut für Mathematik, Rudower Chaussee 25, 12489 Berlin (Germany)
2014-09-15
The harmonic action functional allows a natural generalisation to semi-Riemannian supergeometry, also referred to as harmonic, which resembles the supersymmetric sigma models studied in high energy physics. We show that Killing vector fields are infinitesimal supersymmetries of this harmonic action and prove three different Noether theorems in this context. En passant, we provide a homogeneous treatment of five characterisations of Killing vector fields on semi-Riemannian supermanifolds, thus filling a gap in the literature.
Killing Vector Fields and Superharmonic Field Theories
Groeger, Josua
2013-01-01
The harmonic action functional allows a natural generalisation to semi-Riemannian supergeometry, referred to as superharmonic action, which resembles the supersymmetric sigma models studied in high energy physics. We show that Killing vector fields are infinitesimal supersymmetries of the superharmonic action and prove three different Noether theorems in this context. En passant, we provide a homogeneous treatment of five characterisations of Killing vector fields on semi-Riemannian supermanifolds, thus filling a gap in the literature.
Dynamics of localized structures in vector waves
Hernández-García, E; Colet, P; San Miguel, M; Hernandez-Garcia, Emilio; Hoyuelos, Miguel; Colet, Pere; Miguel, Maxi San
1999-01-01
Dynamical properties of topological defects in a twodimensional complex vector field are considered. These objects naturally arise in the study of polarized transverse light waves. Dynamics is modeled by a Vector Complex Ginzburg-Landau Equation with parameter values appropriate for linearly polarized laser emission. Creation and annihilation processes, and selforganization of defects in lattice structures, are described. We find "glassy" configurations dominated by vectorial defects and a melting process associated to topological-charge unbinding.
Solving Parity Games on Integer Vectors
Abdulla, Parosh Aziz; Mayr, Richard; Sangnier, Arnaud; Sproston, Jeremy
2013-01-01
We consider parity games on infinite graphs where configurations are represented by control-states and integer vectors. This framework subsumes two classic game problems: parity games on vector addition systems with states (vass) and multidimensional energy parity games. We show that the multidimensional energy parity game problem is inter-reducible with a subclass of single-sided parity games on vass where just one player can modify the integer counters and the opponent can only change contr...
Vector database for vehicle road navigation
Kenda, Lian
2007-01-01
Vehicle navigation devices use vector cartographic view, which is designed as a vector database. Database creation begins by setting up a landscape model which includes all the graphical and descriptive data required for accurate vehicle navigation. This paper presents the creation of a database part called StreetConnect, which is used for road navigation. Data obtained using distinct specifications have been transformed into the format compatible with Garmin GPS devices. Data have been obtai...
Vector field processing on triangle meshes
De Goes, Fernando; Desbrun, Mathieu; Tong, Yiying
2015-01-01
While scalar fields on surfaces have been staples of geometry processing, the use of tangent vector fields has steadily grown in geometry processing over the last two decades: they are crucial to encoding directions and sizing on surfaces as commonly required in tasks such as texture synthesis, non-photorealistic rendering, digital grooming, and meshing. There are, however, a variety of discrete representations of tangent vector fields on triangle meshes, and each approach offers different tr...
Improvised microinjection technique for mosquito vectors
Sampath, Kumar S.; H.P.Puttaraju
2012-01-01
Background & objectives: Bio-manipulation technique is of primary importance during the development of transgenic mosquitoes. The study describes the variable factors that influence the viability of medically important mosquito vectors during microinjection. Methods: Three mosquito vectors belonging to the genus Aedes, Anopheles and Culex were microinjected at different developmental stages of their life cycle viz., egg, larvae, pupae and adult. Results: The improvisations revealed an increas...
Null vectors of the $WBC_2$ algebra
Bajnok, Z
1994-01-01
Using the fusion principle of Bauer et al. we give explicit expressions for some null vectors in the highest weight representations of the \\bc algebra in two different forms. These null vectors are the generalization of the Virasoro ones described by Benoit and Saint-Aubin and analogues of the $W_3$ ones constructed by Bowcock and Watts. We find connection between quantum Toda models and the fusion method.
Nonperturbative Aspects of Axial Vector Vertex
Institute of Scientific and Technical Information of China (English)
ZONG Hong-Shi; CHEN Xiang-Song; WANG Fan; CHANG Chao-Hsi; ZHAO En-Guang
2002-01-01
It is shown how the axial vector current of current quarks is related to that of constituent quarks within the framework of the global color symmetry model.Gluon dressing of the axial vector vertex and the quark self-energy functions are described by the inhomogeneous Bethe-Salpeter equation in the ladder approximation and the Schwinger Dyson equation in the rainbow approximation,respectively.
Students' difficulties with vector calculus in electrodynamics
2015-01-01
Understanding Maxwell's equations in differential form is of great importance when studying the electrodynamic phenomena discussed in advanced electromagnetism courses. It is therefore necessary that students master the use of vector calculus in physical situations. In this light we investigated the difficulties second year students at KU Leuven encounter with the divergence and curl of a vector field in mathematical and physical contexts. We have found that they are quite skilled at doing ca...
Lee, Dukhyung; Kim, Dai-Sik
2016-01-07
We study light scattering off rectangular slot nano antennas on a metal film varying incident polarization and incident angle, to examine which field vector of light is more important: electric vector perpendicular to, versus magnetic vector parallel to the long axis of the rectangle. While vector Babinet's principle would prefer magnetic field along the long axis for optimizing slot antenna function, convention and intuition most often refer to the electric field perpendicular to it. Here, we demonstrate experimentally that in accordance with vector Babinet's principle, the incident magnetic vector parallel to the long axis is the dominant component, with the perpendicular incident electric field making a small contribution of the factor of 1/|ε|, the reciprocal of the absolute value of the dielectric constant of the metal, owing to the non-perfectness of metals at optical frequencies.
Effects of Climate and Climate Change on Vectors and Vector-Borne Diseases: Ticks Are Different.
Ogden, Nick H; Lindsay, L Robbin
2016-08-01
There has been considerable debate as to whether global risk from vector-borne diseases will be impacted by climate change. This has focussed on important mosquito-borne diseases that are transmitted by the vectors from infected to uninfected humans. However, this debate has mostly ignored the biological diversity of vectors and vector-borne diseases. Here, we review how climate and climate change may impact those most divergent of arthropod disease vector groups: multivoltine insects and hard-bodied (ixodid) ticks. We contrast features of the life cycles and behaviour of these arthropods, and how weather, climate, and climate change may have very different impacts on the spatiotemporal occurrence and abundance of vectors, and the pathogens they transmit.
An Algorithm for Interpolating Ship Motion Vectors
Directory of Open Access Journals (Sweden)
Qinyou Hu
2014-03-01
Full Text Available Interpolation of ship motion vectors is able to be used for estimating the lost ship AIS dynamic information, which is important for replaying marine accidents and for analysing marine traffic data. The previous methods can only interpolate ship's position, while not including ship's course and speed. In this paper, vector function is used to express the relationship between the ship's time and space coordinates, and the tangent of the vector function and its change rate are able to express physical characteristics of ship's course, speed and acceleration. The given AIS dynamic information can be applied to calculate the parameters of ship's vector function and then the interpolation model for ship motion vectors is developed to estimate the lost ship dynamic information at any given moment. Experiment results show that the ship motion vector function is able to depict the characteristics of ship motions accurately and the model can estimate not only the ship's position but also ship's course and speed at any given moment with limited differences.
An Unbroken Axial Vector Current Conservation Law
Sharafiddinov, Rasulkhozha S
2015-01-01
The mass, energy and momentum of the neutrino of a true flavor have an axial-vector nature. As a consequence, the left-handed truly neutral neutrino in an axial-vector field of emission can be converted into a right-handed one and vice versa. This predicts the unidenticality of masses, energies and momenta of neutrinos of the different components. Recognizing such a difference in masses, energies, momenta and accepting that the left-handed axial-vector neutrino and the right-handed antineutrino of true neutrality refer to long-lived C-odd leptons, and the right-handed truly neutral neutrino and the left-handed axial-vector antineutrino are of short-lived fermions of C-oddity, we would write a new CP-even Dirac equation taking into account the flavor symmetrical axial-vector mass, energy and momentum matrices. Their presence explains the spontaneous mirror symmetry violation, confirming that an axial-vector current conservation law has never violated. They reflect the availability of a mirror Minkowski space i...
Trobridge, Grant; Russell, David W
2004-03-01
Retroviral vectors based on foamy viruses (FV) are efficient gene delivery vehicles for therapeutic and research applications. While previous studies have shown that FV vectors transduce quiescent cell cultures more efficiently than oncoviral vectors, their specific cell cycle requirements have not been determined. Here we compare the transduction frequencies of FV vectors with those of onco- and lentiviral vectors in nondividing and dividing normal human fibroblasts by several methods. FV vectors transduced serum-deprived fibroblast cultures more efficiently than oncoretroviral vectors and at rates comparable to those of lentiviral vectors. However, in these cultures FV vectors only transduced a subpopulation of proliferating cells, as determined by bromodeoxyuridine staining for DNA synthesis. In contrast to lentiviral vectors, FV vectors were unable to transduce human fibroblasts arrested by aphidicolin (G(1)/S phase) or gamma-irradiation (G(2) phase), and a partial cell cycle that included mitosis but not DNA synthesis was required. We could not determine if mitosis facilitated nuclear entry of FV vectors, since cell-free vector preparations contained long terminal repeat circles, precluding their use as nuclear markers. In contrast to oncoviral vectors, both FV and lentiviral vectors efficiently transduced G(0) fibroblasts that were later stimulated to divide. In the case of FV vectors, this was due to the persistence of a stable transduction intermediate in quiescent cells. Our findings support the use of FV vectors as a safe and effective alternative to lentiviral vectors for ex vivo transduction of stem cells that are quiescent during culture but divide following transplantation.
A COMPREHENSIVE ANALYSIS OF SPACE VECTOR PWM TECHNIQUE BASED ON PLACEMENT OF ZERO-SPACE VECTOR
Directory of Open Access Journals (Sweden)
G.SAMBASIVA RAO,
2011-04-01
Full Text Available In this paper, the effect of placement of zero-space vector for the implementation of space vector based Pulse Width Modulation techniques for 3-phase Voltage Source Inverter is presented. Several pulse width modulation (PWM control strategies have been proposed for 3-phase voltage source inverter (VSI in the past. It is known that space vector modulation (SVM offers a degree of freedom in its implementation with regard to the placement of the zero-space vector. Apart from constructing a consistent theoretical framework, simulation results with conventional continuous SVM and various discontinuous SVM techniques are presented and all the cases are compared in this paper.
Viral Vectors for in Vivo Gene Transfer
Thévenot, E.; Dufour, N.; Déglon, N.
The transfer of DNA into the nucleus of a eukaryotic cell (gene transfer) is a central theme of modern biology. The transfer is said to be somatic when it refers to non-germline organs of a developed individual, and germline when it concerns gametes or the fertilised egg of an animal, with the aim of transmitting the relevant genetic modification to its descendents [1]. The efficient introduction of genetic material into a somatic or germline cell and the control of its expression over time have led to major advances in understanding how genes work in vivo, i.e., in living organisms (functional genomics), but also to the development of innovative therapeutic methods (gene therapy). The efficiency of gene transfer is conditioned by the vehicle used, called the vector. Desirable features for a vector are as follows: Easy to produce high titer stocks of the vector in a reproducible way. Absence of toxicity related to transduction (transfer of genetic material into the target cell, and its expression there) and no immune reaction of the organism against the vector and/or therapeutic protein. Stability in the expression of the relevant gene over time, and the possibility of regulation, e.g., to control expression of the therapeutic protein on the physiological level, or to end expression at the end of treatment. Transduction of quiescent cells should be as efficient as transduction of dividing cells. Vectors currently used fall into two categories: non-viral and viral vectors. In non-viral vectors, the DNA is complexed with polymers, lipids, or cationic detergents (described in Chap. 3). These vectors have a low risk of toxicity and immune reaction. However, they are less efficient in vivo than viral vectors when it comes to the number of cells transduced and long-term transgene expression. (Naked DNA transfer or electroporation is rather inefficient in the organism. This type of gene transfer will not be discussed here, and the interested reader is referred to the
New Approach to Fractal Approximation of Vector-Functions
Directory of Open Access Journals (Sweden)
Konstantin Igudesman
2015-01-01
Full Text Available This paper introduces new approach to approximation of continuous vector-functions and vector sequences by fractal interpolation vector-functions which are multidimensional generalization of fractal interpolation functions. Best values of fractal interpolation vector-functions parameters are found. We give schemes of approximation of some sets of data and consider examples of approximation of smooth curves with different conditions.
Inverse Operation of Four-dimensional Vector Matrix
Directory of Open Access Journals (Sweden)
H J Bao
2011-08-01
Full Text Available This is a new series of study to define and prove multidimensional vector matrix mathematics, which includes four-dimensional vector matrix determinant, four-dimensional vector matrix inverse and related properties. There are innovative concepts of multi-dimensional vector matrix mathematics created by authors with numerous applications in engineering, math, video conferencing, 3D TV, and other fields.
40 CFR 503.33 - Vector attraction reduction.
2010-07-01
... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Vector attraction reduction. 503.33... STANDARDS FOR THE USE OR DISPOSAL OF SEWAGE SLUDGE Pathogens and Vector Attraction Reduction § 503.33 Vector attraction reduction. (a)(1) One of the vector attraction reduction requirements in § 503.33 (b)(1)...
Investigation of Optimal Integrated Circuit Raster Image Vectorization Method
Directory of Open Access Journals (Sweden)
Leonas Jasevičius
2011-03-01
Full Text Available Visual analysis of integrated circuit layer requires raster image vectorization stage to extract layer topology data to CAD tools. In this paper vectorization problems of raster IC layer images are presented. Various line extraction from raster images algorithms and their properties are discussed. Optimal raster image vectorization method was developed which allows utilization of common vectorization algorithms to achieve the best possible extracted vector data match with perfect manual vectorization results. To develop the optimal method, vectorized data quality dependence on initial raster image skeleton filter selection was assessed.Article in Lithuanian
Support vector machine applied in QSAR modelling
Institute of Scientific and Technical Information of China (English)
MEI Hu; ZHOU Yuan; LIANG Guizhao; LI Zhiliang
2005-01-01
Support vector machine (SVM), partial least squares (PLS), and Back-Propagation artificial neural network (ANN) were employed to establish QSAR models of 2 dipeptide datasets. In order to validate predictive capabilities on external dataset of the resulting models, both internal and external validations were performed. The division of dataset into both training and test sets was carried out by D-optimal design. The results showed that support vector machine (SVM) behaved well in both calibration and prediction. For the dataset of 48 bitter tasting dipeptides (BTD), the results obtained by support vector regression (SVR) were superior to that by PLS in both calibration and prediction. When compared with BP artificial neural network, SVR showed less calibration power but more predictive capability. For the dataset of angiotensin-converting enzyme (ACE) inhibitors, the results obtained by support vector machine (SVM) regression were equivalent to those by PLS and BP artificial neural network. In both datasets, SVR using linear kernel function behaved well as that using radial basis kernel function. The results showed that there is wide prospect for the application of support vector machine (SVM) into QSAR modeling.
Stability of Horndeski vector-tensor interactions
Energy Technology Data Exchange (ETDEWEB)
Jiménez, Jose Beltrán [Centre for Cosmology, Particle Physics and Phenomenology, Institute of Mathematics and Physics, Louvain University, 2 Chemin du Cyclotron, Louvain-la-Neuve, 1348 (Belgium); Durrer, Ruth; Heisenberg, Lavinia [Département de Physique Théorique and Center for Astroparticle Physics, Université de Genève, 24 quai Ansermet, Genève 4, CH-1211 (Switzerland); Thorsrud, Mikjel, E-mail: jose.beltran@uclouvain.be, E-mail: ruth.durrer@unige.ch, E-mail: lavinia.heisenberg@unige.ch, E-mail: mikjel.thorsrud@astro.uio.no [Institute of Theoretical Astrophysics, University of Oslo, P.O. Box 1029 Blindern, Oslo, N-0315 (Norway)
2013-10-01
We study the Horndeski vector-tensor theory that leads to second order equations of motion and contains a non-minimally coupled abelian gauge vector field. This theory is remarkably simple and consists of only 2 terms for the vector field, namely: the standard Maxwell kinetic term and a coupling to the dual Riemann tensor. Furthermore, the vector sector respects the U(1) gauge symmetry and the theory contains only one free parameter, M{sup 2}, that controls the strength of the non-minimal coupling. We explore the theory in a de Sitter spacetime and study the presence of instabilities and show that it corresponds to an attractor solution in the presence of the vector field. We also investigate the cosmological evolution and stability of perturbations in a general FLRW spacetime. We find that a sufficient condition for the absence of ghosts is M{sup 2} > 0. Moreover, we study further constraints coming from imposing the absence of Laplacian instabilities. Finally, we study the stability of the theory in static and spherically symmetric backgrounds (in particular, Schwarzschild and Reissner-Nordström-de Sitter). We find that the theory, quite generally, do have ghosts or Laplacian instabilities in regions of spacetime where the non-minimal interaction dominates over the Maxwell term. We also calculate the propagation speed in these spacetimes and show that superluminality is a quite generic phenomenon in this theory.
Stability of Horndeski vector-tensor interactions
Jiménez, Jose Beltrán; Heisenberg, Lavinia; Thorsrud, Mikjel
2013-01-01
We study the Horndeski vector-tensor theory that leads to second order equations of motion and contains a non-minimally coupled abelian gauge vector field. This theory is remarkably simple and consists of only 2 terms for the vector field, namely: the standard Maxwell kinetic term and a coupling to the dual Riemann tensor. Furthermore, the vector sector respects the U(1) gauge symmetry and the theory contains only one free parameter, M^2, that controls the strength of the non-minimal coupling. We explore the theory in a de Sitter spacetime and study the presence of instabilities and show that it corresponds to an attractor solution in the presence of the vector field. We also investigate the cosmological evolution and stability of perturbations in a general FLRW spacetime. We find that a sufficient condition for the absence of ghosts is M^2>0. Moreover, we study further constraints coming from imposing the absence of Laplacian instabilities. Finally, we study the stability of the theory in static and spherica...
Stability of Horndeski vector-tensor interactions
Beltrán Jiménez, Jose; Durrer, Ruth; Heisenberg, Lavinia; Thorsrud, Mikjel
2013-10-01
We study the Horndeski vector-tensor theory that leads to second order equations of motion and contains a non-minimally coupled abelian gauge vector field. This theory is remarkably simple and consists of only 2 terms for the vector field, namely: the standard Maxwell kinetic term and a coupling to the dual Riemann tensor. Furthermore, the vector sector respects the U(1) gauge symmetry and the theory contains only one free parameter, M2, that controls the strength of the non-minimal coupling. We explore the theory in a de Sitter spacetime and study the presence of instabilities and show that it corresponds to an attractor solution in the presence of the vector field. We also investigate the cosmological evolution and stability of perturbations in a general FLRW spacetime. We find that a sufficient condition for the absence of ghosts is M2 > 0. Moreover, we study further constraints coming from imposing the absence of Laplacian instabilities. Finally, we study the stability of the theory in static and spherically symmetric backgrounds (in particular, Schwarzschild and Reissner-Nordström-de Sitter). We find that the theory, quite generally, do have ghosts or Laplacian instabilities in regions of spacetime where the non-minimal interaction dominates over the Maxwell term. We also calculate the propagation speed in these spacetimes and show that superluminality is a quite generic phenomenon in this theory.
Dynamical Symmetry Breaking with Vector Bosons
Cynolter, G; Pócsik, G
2004-01-01
In the standard model of electroweak interactions the Higgs doublet is replaced by a complex vector doublet and a real vector singlet. The gauge symmetry is broken dynamically by a mixed condensate of the doublet and singlet vector fields. Gauge fields get their usual standard model masses by condensation. The new vector matter fields become massive by their gauge invariant selfcouplings and expected to have masses of few hundred GeV. Fermions are assigned to the gauge group in the usual manner. Fermion masses are coming from a gauge invariant fermion-vector field interaction by a mixed condensat, the Kobayashi-Maskawa description is unchanged. Perturbative unitarity estimates show that the model is valid up to 2-3 TeV. It is shown that from the new matter fields a large number of spin-one particle pairs is expected at future high energy e^{+}e^{-} linear colliders of 500-1500 GeV. The inclusive production cross section of new particle pairs is presented for hadron colliders, while at the Tevatron the new par...
Perceptual vector quantization for video coding
Valin, Jean-Marc; Terriberry, Timothy B.
2015-03-01
This paper applies energy conservation principles to the Daala video codec using gain-shape vector quantization to encode a vector of AC coefficients as a length (gain) and direction (shape). The technique originates from the CELT mode of the Opus audio codec, where it is used to conserve the spectral envelope of an audio signal. Conserving energy in video has the potential to preserve textures rather than low-passing them. Explicitly quantizing a gain allows a simple contrast masking model with no signaling cost. Vector quantizing the shape keeps the number of degrees of freedom the same as scalar quantization, avoiding redundancy in the representation. We demonstrate how to predict the vector by transforming the space it is encoded in, rather than subtracting off the predictor, which would make energy conservation impossible. We also derive an encoding of the vector-quantized codewords that takes advantage of their non-uniform distribution. We show that the resulting technique outperforms scalar quantization by an average of 0.90 dB on still images, equivalent to a 24.8% reduction in bitrate at equal quality, while for videos, the improvement averages 0.83 dB, equivalent to a 13.7% reduction in bitrate.
LHC Signatures of Vector-Like Quarks
Directory of Open Access Journals (Sweden)
Yasuhiro Okada
2013-01-01
Full Text Available This work provides an overview on the current status of phenomenology and searches for heavy vector-like quarks, which are predicted in many models of new physics beyond the Standard Model. Searches at Tevatron and at the LHC, here listed and shortly described, have not found any evidence for new heavy fermionic states (either chiral or vector-like and have therefore posed strong bounds on their masses: depending on specific assumptions on the interactions and on the observed final state, vector-like quarks with masses up to roughly 400–600 GeV have been excluded by all experiments. In order to be as simple and model independent as possible, the chosen framework for the phenomenological analysis is an effective model with the addition of a vector-like quark representation (singlet, doublet, or triplet under SU(2L which couples through Yukawa interactions with all SM families. The relevance of different observables for the determination of bounds on mixing parameters is then discussed and a complete overview of possible two body final states for every vector-like quark is provided, including their subsequent decay into SM particles. A list and short description of phenomenological analyses present in the literature are also provided for reference purposes.
Affine conformal vectors in space-time
Coley, A. A.; Tupper, B. O. J.
1992-05-01
All space-times admitting a proper affine conformal vector (ACV) are found. By using a theorem of Hall and da Costa, it is shown that such space-times either (i) admit a covariantly constant vector (timelike, spacelike, or null) and the ACV is the sum of a proper affine vector and a conformal Killing vector or (ii) the space-time is 2+2 decomposable, in which case it is shown that no ACV can exist (unless the space-time decomposes further). Furthermore, it is proved that all space-times admitting an ACV and a null covariantly constant vector (which are necessarily generalized pp-wave space-times) must have Ricci tensor of Segré type {2,(1,1)}. It follows that, among space-times admitting proper ACV, the Einstein static universe is the only perfect fluid space-time, there are no non-null Einstein-Maxwell space-times, and only the pp-wave space-times are representative of null Einstein-Maxwell solutions. Otherwise, the space-times can represent anisotropic fluids and viscous heat-conducting fluids, but only with restricted equations of state in each case.
Improved Coinfection with Amphotropic Pseudotyped Retroviral Vectors
Directory of Open Access Journals (Sweden)
Yuehong Wu
2009-01-01
Full Text Available Amphotropic pseudotyped retroviral vectors have typically been used to infect target cells without prior concentration. Although this can yield high rates of infection, higher rates may be needed where highly efficient coinfection of two or more vectors is needed. In this investigation we used amphotropic retroviral vectors produced by the Plat-A cell line and studied coinfection rates using green and red fluorescent proteins (EGFP and dsRed2. Target cells were primary human fibroblasts (PHF and 3T3 cells. Unconcentrated vector preparations produced a coinfection rate of ∼4% (defined as cells that are both red and green as a percentage of all cells infected. Optimized spinoculation, comprising centrifugation at 1200 g for 2 hours at 15∘C, increased the coinfection rate to ∼10%. Concentration by centrifugation at 10,000 g or by flocculation using Polybrene increased the coinfection rate to ∼25%. Combining the two processes, concentration by Polybrene flocculation and optimized spinoculation, increased the coinfection rate to 35% (3T3 or >50% (PHF. Improved coinfection should be valuable in protocols that require high transduction by combinations of two or more retroviral vectors.
Test of Understanding of Vectors: A Reliable Multiple-Choice Vector Concept Test
Barniol, Pablo; Zavala, Genaro
2014-01-01
In this article we discuss the findings of our research on students' understanding of vector concepts in problems without physical context. First, we develop a complete taxonomy of the most frequent errors made by university students when learning vector concepts. This study is based on the results of several test administrations of open-ended…
Reduced Order Model Basis Vector Generation: Generates Basis Vectors fro ROMs
Energy Technology Data Exchange (ETDEWEB)
2016-03-03
libROM is a library that implements order reduction via singular value decomposition (SVD) of sampled state vectors. It implements 2 parallel, incremental SVD algorithms and one serial, non-incremental algorithm. It also provides a mechanism for adaptive sampling of basis vectors.
Energy Technology Data Exchange (ETDEWEB)
Adachi, Masaaki; Ogasawara, Shinobu; Kume, Etsuo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Ishizuki, Shigeru; Nemoto, Toshiyuki; Kawasaki, Nobuo; Kawai, Wataru [Fujitsu Ltd., Tokyo (Japan); Yatake, Yo-ichi [Hitachi Ltd., Tokyo (Japan)
2001-02-01
Several computer codes in the nuclear field have been vectorized, parallelized and trans-ported on the FUJITSU VPP500 system, the AP3000 system, the SX-4 system and the Paragon system at Center for Promotion of Computational Science and Engineering in Japan Atomic Energy Research Institute. We dealt with 18 codes in fiscal 1999. These results are reported in 3 parts, i.e., the vectorization and the parallelization part on vector processors, the parallelization part on scalar processors and the porting part. In this report, we describe the vectorization and parallelization on vector processors. In this vectorization and parallelization on vector processors part, the vectorization of Relativistic Molecular Orbital Calculation code RSCAT, a microscopic transport code for high energy nuclear collisions code JAM, three-dimensional non-steady thermal-fluid analysis code STREAM, Relativistic Density Functional Theory code RDFT and High Speed Three-Dimensional Nodal Diffusion code MOSRA-Light on the VPP500 system and the SX-4 system are described. (author)
Auto-tuning Dense Vector and Matrix-vector Operations for Fermi GPUs
DEFF Research Database (Denmark)
Sørensen, Hans Henrik Brandenborg
2012-01-01
In this paper, we consider the automatic performance tuning of dense vector and matrix-vector operations on GPUs. Such operations form the backbone of level 1 and level 2 routines in the Basic Linear Algebra Subroutines (BLAS) library and are therefore of great importance in many scientific...... for dense vector and matrix-vector operations by appropriately utilizing the fine-grained parallelism of the GPU. Our tuned kernels display between 25-100% better performance than the current CUBLAS 3.2 library....... applications. As examples, we develop single-precision CUDA kernels for the Euclidian norm (SNRM2) and the matrix-vector multiplication (SGEMV). The target hardware is the most recent Nvidia Tesla 20-series (Fermi architecture). We show that auto-tuning can be successfully applied to achieve high performance...
Concircular $\\pi$-Vector Fields and Special Finsler Spaces
Youssef, Nabil L.; Soleiman, A
2012-01-01
The aim of the present paper is to investigate intrinsically the notion of a concircular $\\pi$-vector field in Finsler geometry. This generalizes the concept of a concircular vector field in Riemannian geometry and the concept of a concurrent vector field in Finsler geometry. Some properties of concircular $\\pi$-vector fields are obtained. Different types of recurrence are discussed. The effect of the existence of a concircular $\\pi$-vector field on some important special Finsler spaces is in...
GENERALIZED VECTOR VARIATIONAL-TYPE INEQUALITIES IN FC-SPACES
Institute of Scientific and Technical Information of China (English)
FANG Min; DING Xie-ping
2006-01-01
A class of generalized vector variational-type inequality problems (GVVTIP) are studied in FC-spaces, which includes the most of vector equilibrium problems, vector variational inequality problems, generalized vector equilibrium problems and generalized vector variational inequality problem as special cases. By using F-KKM theorem,some new existence results for GVVTIP are established in noncompact FC-space. As consequences, some recent known results in literature are obtained under much weaker assumption.
Emergence and prevalence of human vector-borne diseases in sink vector populations.
Directory of Open Access Journals (Sweden)
Guilhem Rascalou
Full Text Available Vector-borne diseases represent a major public health concern in most tropical and subtropical areas, and an emerging threat for more developed countries. Our understanding of the ecology, evolution and control of these diseases relies predominantly on theory and data on pathogen transmission in large self-sustaining 'source' populations of vectors representative of highly endemic areas. However, there are numerous places where environmental conditions are less favourable to vector populations, but where immigration allows them to persist. We built an epidemiological model to investigate the dynamics of six major human vector borne-diseases in such non self-sustaining 'sink' vector populations. The model was parameterized through a review of the literature, and we performed extensive sensitivity analysis to look at the emergence and prevalence of the pathogen that could be encountered in these populations. Despite the low vector abundance in typical sink populations, all six human diseases were able to spread in 15-55% of cases after accidental introduction. The rate of spread was much more strongly influenced by vector longevity, immigration and feeding rates, than by transmission and virulence of the pathogen. Prevalence in humans remained lower than 5% for dengue, leishmaniasis and Japanese encephalitis, but substantially higher for diseases with longer duration of infection; malaria and the American and African trypanosomiasis. Vector-related parameters were again the key factors, although their influence was lower than on pathogen emergence. Our results emphasize the need for ecology and evolution to be thought in the context of metapopulations made of a mosaic of sink and source habitats, and to design vector control program not only targeting areas of high vector density, but working at a larger spatial scale.
Heavy vector and axial-vector mesons in hot and dense asymmetric strange hadronic matter
Kumar, Arvind; Chhabra, Rahul
2015-09-01
We calculate the effects of finite density and temperature of isospin asymmetric strange hadronic matter, for different strangeness fractions, on the in-medium properties of vector (D*,Ds*,B*,Bs*) and axial-vector (D1,D1 s,B1,B1 s) mesons, using the chiral hadronic SU(3) model and QCD sum rules. We focus on the evaluation of in-medium mass-shift and shift in decay constant of above vector and axial-vector mesons. In the quantum chromodynamics sum rule approach, the properties, e.g., the masses and decay constants of vector and axial-vector mesons are written in terms of quark and gluon condensates. These quark and gluon condensates are evaluated in the present work within the chiral SU(3) model, through the medium modification of scalar-isoscalar fields σ and ζ , the scalar-isovector field δ , and the scalar dilaton field χ , in the strange hadronic medium which includes both nucleons as well as hyperons. As we shall see in detail, the masses and decay constants of heavy vector and axial-vector mesons are affected significantly from isospin asymmetry and the strangeness fraction of the medium, and these modifications may influence the experimental observables produced in heavy-ion collision experiments. The results of present investigations of in-medium properties of vector and axial-vector mesons at finite density and temperature of strange hadronic medium may be helpful for understanding the experimental data from heavy-ion collision experiments in particular for the compressed baryonic matter (CBM) experiment of the FAIR facility at GSI, Germany.
Partial Transfer Entropy on Rank Vectors
Kugiumtzis, Dimitris
2013-01-01
For the evaluation of information flow in bivariate time series, information measures have been employed, such as the transfer entropy (TE), the symbolic transfer entropy (STE), defined similarly to TE but on the ranks of the components of the reconstructed vectors, and the transfer entropy on rank vectors (TERV), similar to STE but forming the ranks for the future samples of the response system with regard to the current reconstructed vector. Here we extend TERV for multivariate time series, and account for the presence of confounding variables, called partial transfer entropy on ranks (PTERV). We investigate the asymptotic properties of PTERV, and also partial STE (PSTE), construct parametric significance tests under approximations with Gaussian and gamma null distributions, and show that the parametric tests cannot achieve the power of the randomization test using time-shifted surrogates. Using simulations on known coupled dynamical systems and applying parametric and randomization significance tests, we s...
Improving DNA vaccine performance through vector design.
Williams, James A
2014-01-01
DNA vaccines are a rapidly deployed next generation vaccination platform for treatment of human and animal disease. DNA delivery devices, such as electroporation and needle free jet injectors, are used to increase gene transfer. This results in higher antigen expression which correlates with improved humoral and cellular immunity in humans and animals. This review highlights recent vector and transgene design innovations that improve DNA vaccine performance. These new vectors improve antigen expression, increase plasmid manufacturing yield and quality in bioreactors, and eliminate antibiotic selection and other potential safety issues. A flowchart for designing synthetic antigen transgenes, combining antigen targeting, codon-optimization and bioinformatics, is presented. Application of improved vectors, of antibiotic free plasmid production, and cost effective manufacturing technologies will be critical to ensure safety, efficacy, and economically viable manufacturing of DNA vaccines currently under development for infectious disease, cancer, autoimmunity, immunotolerance and allergy indications.
Molecular Epidemiology for Vector Research on Leishmaniasis
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Hirotomo Kato
2010-03-01
Full Text Available Leishmaniasis is a protozoan disease caused by the genus Leishmania transmitted by female phlebotomine sand flies. Surveillance of the prevalence of Leishmania and responsive vector species in endemic and surrounding areas is important for predicting the risk and expansion of the disease. Molecular biological methods are now widely applied to epidemiological studies of infectious diseases including leishmaniasis. These techniques are used to detect natural infections of sand fly vectors with Leishmania protozoa and are becoming powerful tools due to their sensitivity and specificity. Recently, genetic analyses have been performed on sand fly species and genotyping using PCR-RFLP has been applied to the sand fly taxonomy. In addition, a molecular mass screening method has been established that enables both sand fly species and natural leishmanial infections to be identified simultaneously in hundreds of sand flies with limited effort. This paper reviews recent advances in the study of sand flies, vectors of leishmaniasis, using molecular biological approaches.
Replicon RNA Viral Vectors as Vaccines
Lundstrom, Kenneth
2016-01-01
Single-stranded RNA viruses of both positive and negative polarity have been used as vectors for vaccine development. In this context, alphaviruses, flaviviruses, measles virus and rhabdoviruses have been engineered for expression of surface protein genes and antigens. Administration of replicon RNA vectors has resulted in strong immune responses and generation of neutralizing antibodies in various animal models. Immunization of mice, chicken, pigs and primates with virus-like particles, naked RNA or layered DNA/RNA plasmids has provided protection against challenges with lethal doses of infectious agents and administered tumor cells. Both prophylactic and therapeutic efficacy has been achieved in cancer immunotherapy. Moreover, recombinant particles and replicon RNAs have been encapsulated by liposomes to improve delivery and targeting. Replicon RNA vectors have also been subjected to clinical trials. Overall, immunization with self-replicating RNA viruses provides high transient expression levels of antigens resulting in generation of neutralizing antibody responses and protection against lethal challenges under safe conditions. PMID:27827980
Genetic Modification of Baculovirus Expression Vectors
Institute of Scientific and Technical Information of China (English)
Shu-fen Li; Hua-lin Wang; Zhi-hong Hu; Fei Deng
2012-01-01
As a protein expression vector,the baculovirus demonstrates many advantages over other vectors.With the development of biotechnology,baculoviral vectors have been genetically modified to facilitate high level expression of heterologous proteins in both insect and mammalian cells.These modifications include utilization of different promoters and signal peptides,deletion or replacement of viral genes for increasing protein secretion,integration of polycistronic expression cassette for producing protein complexes,and baculovirus pseudotyping,promoter accommodation or surface display for enhancing mammalian cell targeting gene delivery.This review summarizes the development and the current state of art of the baculovirus expression system.Further development of baculovirus expression systems will make them even more feasible and accessible for advanced applications.
Weyl node with random vector potential
Sbierski, Björn; Decker, Kevin S. C.; Brouwer, Piet W.
2016-12-01
We study Weyl semimetals in the presence of generic disorder, consisting of a random vector potential as well as a random scalar potential. We derive renormalization group flow equations to second order in the disorder strength. These flow equations predict a disorder-induced phase transition between a pseudoballistic weak-disorder phase and a diffusive strong-disorder phase for a sufficiently strong random scalar potential or for a pure three-component random vector potential. We verify these predictions using a numerical study of the density of states near the Weyl point and of quantum transport properties at the Weyl point. In contrast, for a pure single-component random vector potential, the diffusive strong-disorder phase is absent.
Insect Vectors of Rice Yellow Mottle Virus
Directory of Open Access Journals (Sweden)
Augustin Koudamiloro
2015-01-01
Full Text Available Rice yellow mottle virus (RYMV is the major viral constraint to rice production in Africa. RYMV was first identified in 1966 in Kenya and then later in most African countries where rice is grown. Several studies have been conducted so far on its evolution, pathogenicity, resistance genes, and especially its dissemination by insects. Many of these studies showed that, among RYMV vectors, insects especially leaf-feeders found in rice fields are the major source of virus transmission. Many studies have shown that the virus is vectored by several insect species in a process of a first ingestion of leaf material and subsequent transmission in following feedings. About forty insect species were identified as vectors of RYMV since 1970 up to now. They were essentially the beetles, grasshoppers, and the leafhoppers. For this review, we presented the chronology of their identification. Also, the biology, ecology, host range, distribution, and caused damage of these insects were briefly summarized.
Measuring vector magnetic fields in solar prominences
Suárez, D Orozco; Bueno, J Trujillo
2012-01-01
We present spectropolarimetric observations in the He I 1083.0 nm multiplet of a quiescent, hedgerow solar prominence. The data were taken with the Tenerife Infrared Polarimeter attached to the German Vacuum Tower Telescope at the Observatorio del Teide (Tenerife; Canary Islands; Spain). The observed He I circular and linear polarization signals are dominated by the Zeeman effect and by atomic level polarization and the Hanle effect, respectively. These observables are sensitive to the strength and orientation of the magnetic field vector at each spatial point of the field of view. We determine the magnetic field vector of the prominence by applying the HAZEL inversion code to the observed Stokes profiles. We briefly discuss the retrieved magnetic field vector configuration.
Axial symmetry and conformal Killing vectors
Mars, M; Mars, Marc; Senovilla, Jose M.M.
1993-01-01
Axisymmetric spacetimes with a conformal symmetry are studied and it is shown that, if there is no further conformal symmetry, the axial Killing vector and the conformal Killing vector must commute. As a direct consequence, in conformally stationary and axisymmetric spacetimes, no restriction is made by assuming that the axial symmetry and the conformal timelike symmetry commute. Furthermore, we prove that in axisymmetric spacetimes with another symmetry (such as stationary and axisymmetric or cylindrically symmetric spacetimes) and a conformal symmetry, the commutator of the axial Killing vector with the two others mush vanish or else the symmetry is larger than that originally considered. The results are completely general and do not depend on Einstein's equations or any particular matter content.
Review of Scalars, Vectors, Tensors, and Dyads
Schnack, Dalton D.
In MHD, we will deal with relationships between quantities such as the magnetic field and the velocity that have both magnitude and direction. These quantities are examples of vectors (or, as we shall soon see, pseudovectors). The basic concepts of scalar and vector quantities are introduced early in any scientific education. However, to formulate the laws of MHD precisely, it will be necessary to generalize these ideas and to introduce the less familiar concepts of matrices, tensors, and dyads. The ability to understand and manipulate these abstract mathematical concepts is essential to learning MHD. Therefore, for the sake of both reference and completeness, this lecture is about the mathematical properties of scalars, vectors, matrices, tensors, and dyads. If you are already an expert, or think you are, please skip class and go on to Lecture 3. You can always refer back here if needed!
Covariant Lyapunov vectors for rigid disk systems.
Bosetti, Hadrien; Posch, Harald A
2010-10-05
We carry out extensive computer simulations to study the Lyapunov instability of a two-dimensional hard-disk system in a rectangular box with periodic boundary conditions. The system is large enough to allow the formation of Lyapunov modes parallel to the x-axis of the box. The Oseledec splitting into covariant subspaces of the tangent space is considered by computing the full set of covariant perturbation vectors co-moving with the flow in tangent space. These vectors are shown to be transversal, but generally not orthogonal to each other. Only the angle between covariant vectors associated with immediate adjacent Lyapunov exponents in the Lyapunov spectrum may become small, but the probability of this angle to vanish approaches zero. The stable and unstable manifolds are transverse to each other and the system is hyperbolic.
Interactions between parasites and insects vectors
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Hilary Hurd
1994-01-01
Full Text Available This review stresses the importance of studies that will provide a basic understanding of the pathology of parasite-infected vector insects. This knowledge should be a vital component of the very focussed initiatives currently being funded in the areas of vector control. Vector fecundity reduction is discussed as an example of such pathology. Underlying mechanisms are being investigated in a model system, Hymenolepis diminuta-infected Tenebrio molitor and in Onchocerca-infected blackflies and Plasmodium-infected Anopheles stephensi. In all cases, host vitellogenesis is disrupted by the parasite and, in the tapeworm/beetle model, interaction between the parasite and the endocrine control of the insect's reproductive physiology has been demonstrated.
Masquerade Detection Using Support Vector Machine
Institute of Scientific and Technical Information of China (English)
YANG Min; WANG Li-na; ZHANG Huan-guo; CHEN Wei
2005-01-01
A new method using support vector data description (SVDD) to distinguish legitimate users from masqueraders based on UNIX user command sequences is proposed. Sliding windows are used to get low detection delay.Experiments demonstrate that the detection effect using en riched sequences is better than that of using truncated sequences. As a SVDD profile is composed of a small amount of support vectors, our SVDD-based method can achieve computation and storage advantage when the detection performance is similar to existing method.
Integrated vector management for malaria control
Directory of Open Access Journals (Sweden)
Impoinvil Daniel E
2008-12-01
Full Text Available Abstract Integrated vector management (IVM is defined as "a rational decision-making process for the optimal use of resources for vector control" and includes five key elements: 1 evidence-based decision-making, 2 integrated approaches 3, collaboration within the health sector and with other sectors, 4 advocacy, social mobilization, and legislation, and 5 capacity-building. In 2004, the WHO adopted IVM globally for the control of all vector-borne diseases. Important recent progress has been made in developing and promoting IVM for national malaria control programmes in Africa at a time when successful malaria control programmes are scaling-up with insecticide-treated nets (ITN and/or indoor residual spraying (IRS coverage. While interventions using only ITNs and/or IRS successfully reduce transmission intensity and the burden of malaria in many situations, it is not clear if these interventions alone will achieve those critical low levels that result in malaria elimination. Despite the successful employment of comprehensive integrated malaria control programmes, further strengthening of vector control components through IVM is relevant, especially during the "end-game" where control is successful and further efforts are required to go from low transmission situations to sustained local and country-wide malaria elimination. To meet this need and to ensure sustainability of control efforts, malaria control programmes should strengthen their capacity to use data for decision-making with respect to evaluation of current vector control programmes, employment of additional vector control tools in conjunction with ITN/IRS tactics, case-detection and treatment strategies, and determine how much and what types of vector control and interdisciplinary input are required to achieve malaria elimination. Similarly, on a global scale, there is a need for continued research to identify and evaluate new tools for vector control that can be integrated with
Novel cloning vectors for Bacillus thuringiensis.
Baum, J A; Coyle, D M; Gilbert, M P; Jany, C S; Gawron-Burke, C
1990-01-01
Seven replication origins from resident plasmids of Bacillus thuringienis subsp. kurstaki HD263 and HD73 were cloned in Escherichia coli. Three of these replication origins, originating from plasmids of 43, 44, and 60 MDa, were used to construct a set of compatible shuttle vectors that exhibit structural and segregational stability in the Cry- strain B. thuringiensis HD73-26. These shuttle vectors, pEG597, pEG853, and pEG854, were designed with rare restriction sites that permit various adapt...
Craig, Nathaniel; Knapen, Simon; Longhi, Pietro; Strassler, Matthew
2016-07-01
We present a version of the twin Higgs mechanism with vector-like top partners. In this setup all gauge anomalies automatically cancel, even without twin leptons. The matter content of the most minimal twin sector is therefore just two twin tops and one twin bottom. The LHC phenomenology, illustrated with two example models, is dominated by twin glueball decays, possibly in association with Higgs bosons. We further construct an explicit four-dimensional UV completion and discuss a variety of UV completions relevant for both vector-like and fraternal twin Higgs models.
Craig, Nathaniel; Longhi, Pietro; Strassler, Matthew
2016-01-01
We present a version of the twin Higgs mechanism with vector-like top partners. In this setup all gauge anomalies automatically cancel, even without twin leptons. The matter content of the most minimal twin sector is therefore just two twin tops and one twin bottom. The LHC phenomenology, illustrated with two example models, is dominated by twin glueball decays, possibly in association with Higgs bosons. We further construct an explicit four-dimensional UV completion and discuss a variety of UV completions relevant for both vector-like and fraternal twin Higgs models.
Problem signatures from enhanced vector autoregressive modeling
Andriamanalimanana, Bruno R.; Sengupta, Saumen S.
2001-09-01
The work reported in this paper concerns the enhancement of mutivariate autoregressive (AR) models with geometric shape analysis data and stochastic causal relations. The study aims at producing numerical signatures characterizing operating problems, from multivariate time series of data collected in an application and operating environment domain. Since the information content of an AR model does not appear sufficient to characterize observed vector values fully, both geometric and stochastic modeling techniques are applied to refine causal inferences further. The specific application domain used for this study is real-time network traffic monitoring. However, other domains utilizing vector models might benefit as well. A partial Java implementation is being used for experimentation.
Retrotransposon vectors for gene delivery in plants
Directory of Open Access Journals (Sweden)
Hou Yi
2010-08-01
Full Text Available Abstract Background Retrotransposons are abundant components of plant genomes, and although some plant retrotransposons have been used as insertional mutagens, these mobile genetic elements have not been widely exploited for plant genome manipulation. In vertebrates and yeast, retrotransposons and retroviruses are routinely altered to carry additional genes that are copied into complementary (cDNA through reverse transcription. Integration of cDNA results in gene delivery; recombination of cDNA with homologous chromosomal sequences can create targeted gene modifications. Plant retrotransposon-based vectors, therefore, may provide new opportunities for plant genome engineering. Results A retrotransposon vector system was developed for gene delivery in plants based on the Tnt1 element from Nicotiana tabacum. Mini-Tnt1 transfer vectors were constructed that lack coding sequences yet retain the 5' and 3' long terminal repeats (LTRs and adjacent cis sequences required for reverse transcription. The internal coding region of Tnt1 was replaced with a neomycin phosphotransferase gene to monitor replication by reverse transcription. Two different mini-Tnt1 s were developed: one with the native 5' LTR and the other with a chimeric 5' LTR that had the first 233 bp replaced by the CaMV 35 S promoter. After transfer into tobacco protoplasts, both vectors undergo retrotransposition using GAG and POL proteins provided in trans by endogenous Tnt1 elements. The transposition frequencies of mini-Tnt1 vectors are comparable with native Tnt1 elements, and like the native elements, insertion sites are within or near coding sequences. In this paper, we provide evidence that template switching occurs during mini-Tnt1 reverse transcription, indicating that multiple copies of Tnt1 mRNA are packaged into virus-like particles. Conclusions Our data demonstrate that mini-Tnt1 vectors can replicate efficiently in tobacco cells using GAG and POL proteins provided in trans by
Parasitic diseases in humans transmitted by vectors.
Cholewiński, Marcin; Derda, Monika; Hadaś, Edward
2015-01-01
Despite the considerable progress of medicine, parasitic diseases still pose a great threat to human health and life. Among parasitic diseases, those transmitted by vectors, mainly arthropods, play a particular role. These diseases occur most frequently in the poorest countries and affect a vast part of the human population. They include malaria, babesiosis, trypanosomiasis, leishmaniasis and filariasis. This study presents those vector-transmitted diseases that are responsible for the greatest incidence and mortality of people on a global scale. Attention is focused primarily on diseases transmitted by mosquitoes, flies, Hemiptera and ticks.
Stability Analysis of Path-vector Routing
Dimitri, Papadimitriou
2012-01-01
Most studies on path-vector routing stability have been conducted empirically by means of ad-hoc analysis of BGP data traces. None of them consider prior specification of an analytic method including the use of stability measurement metrics for the systematic analysis of BGP traces and associated meta-processing for determining the local state of the routing system. In this paper, we define a set of metrics that characterize the local stability properties of path-vector routing such as BGP (Border Gateway Protocol). By means of these stability metrics, we propose a method to analyze the effects of BGP policy- and protocol-induced instability on local routers.
Analysis of Path-vector Routing Stability
Dimitri, Papadimitriou
2012-01-01
Most studies on path-vector routing stability have been conducted empirically by means of ad-hoc analysis of BGP data traces. None of them consider prior specification of an analytic method including the use of stability measurement metrics for the systematic analysis of BGP traces and associated meta-processing for determining the local state of the routing system. In this paper, we define a set of metrics that characterize the local stability properties of path-vector routing such as BGP (Border Gateway Protocol). By means of these stability metrics, we propose a method to analyze the effects of BGP policy- and protocol-induced instability on local routers.
Diffractive vector meson leptoproduction and spin effects
Goloskokov, S V
2006-01-01
We analyse spin effects in diffractive vector meson leptoproduction at small $x$ on the basis of the generalized parton distribution (GPD) approach. We take into account quark transverse degrees of freedom in the hard subprocess. We calculate amplitudes for the longitudinally and transversely polarized photons and vector mesons. Our results on the cross section and spin density matrix elements (SDME) are in fair agreement with the DESY experiments. Predictions for HERMES and COMPASS energy range are made. The predicted double spin longitudinal $A_{LL}$ asymmetry is not small at HERMES energies
Vector Fields European user group meeting
2007-01-01
The "Vector Fields European user group meeting" will take place at CERN on 26 and 27 September 2007. Within this framework two workshops are organized at the CERN Training Centre: 24 September 2007 Modelling Magnets with Opera 25 September 2007 Modelling of Charged Particle Beam Devices with Opera If you are interested in attending the workshop or the user group meeting please contact Julie Shepherd (Vector Fields) or Pierre Baehler (CERN) directly at: Julie.Shepherd@vectorfields.co.uk, +44 (0) 1865 854933 or +44 (0) 1865 370151 Pierre.Baehler@cern.ch, 75016 / 160156.
Variable ordering structures in vector optimization
Eichfelder, Gabriele
2014-01-01
This book provides an introduction to vector optimization with variable ordering structures, i.e., to optimization problems with a vector-valued objective function where the elements in the objective space are compared based on a variable ordering structure: instead of a partial ordering defined by a convex cone, we see a whole family of convex cones, one attached to each element of the objective space. The book starts by presenting several applications that have recently sparked new interest in these optimization problems, and goes on to discuss fundamentals and important results on a wide ra
Vector Meson Masses in Chiral Perturbation Theory
Bijnens, J; Talavera, P
1997-01-01
We discuss the vector meson masses within the context of Chiral Perturbation Theory performing an expansion in terms of the momenta, quark masses and 1/Nc. We extend the previous analysis to include isospin breaking effects and also include up to order p^4. We discuss vector meson chiral perturbation theory in some detail and present a derivation from a relativistic lagrangian. The unknown coefficients are estimated in various ways. We also discuss the relevance of electromagnetic corrections and the implications of the present calculation for the determination of quark masses.
Comparaciones Multivariantes de Vectores Aleatorios con Aplicaciones
2012-01-01
El resultado de un experimento es variable y está modelado por variables y vectores aleatorios. Comúnmente, las comparaciones entre están cantidades aleatorias están basadas en algunas medidas asociadas, pero a menudo no son demasiado informativas. En este caso, los órdenes estocásticos proporcionan una comparación más completa. A veces, estamos interesados en estudiar propiedades de una variable o vector aleatorio, es decir, sus propiedades de envejecimiento. Los órdenes estocásticos son tam...
Vector Fields and Flows on Differentiable Stacks
DEFF Research Database (Denmark)
A. Hepworth, Richard
2009-01-01
This paper introduces the notions of vector field and flow on a general differentiable stack. Our main theorem states that the flow of a vector field on a compact proper differentiable stack exists and is unique up to a uniquely determined 2-cell. This extends the usual result on the existence...... and uniqueness of flows on a manifold as well as the author's existing results for orbifolds. It sets the scene for a discussion of Morse Theory on a general proper stack and also paves the way for the categorification of other key aspects of differential geometry such as the tangent bundle and the Lie algebra...
Directory of Open Access Journals (Sweden)
Kenichi W Okamoto
2016-03-01
Full Text Available Many vector-borne diseases lack effective vaccines and medications, and the limitations of traditional vector control have inspired novel approaches based on using genetic engineering to manipulate vector populations and thereby reduce transmission. Yet both the short- and long-term epidemiological effects of these transgenic strategies are highly uncertain. If neither vaccines, medications, nor transgenic strategies can by themselves suffice for managing vector-borne diseases, integrating these approaches becomes key. Here we develop a framework to evaluate how clinical interventions (i.e., vaccination and medication can be integrated with transgenic vector manipulation strategies to prevent disease invasion and reduce disease incidence. We show that the ability of clinical interventions to accelerate disease suppression can depend on the nature of the transgenic manipulation deployed (e.g., whether vector population reduction or replacement is attempted. We find that making a specific, individual strategy highly effective may not be necessary for attaining public-health objectives, provided suitable combinations can be adopted. However, we show how combining only partially effective antimicrobial drugs or vaccination with transgenic vector manipulations that merely temporarily lower vector competence can amplify disease resurgence following transient suppression. Thus, transgenic vector manipulation that cannot be sustained can have adverse consequences-consequences which ineffective clinical interventions can at best only mitigate, and at worst temporarily exacerbate. This result, which arises from differences between the time scale on which the interventions affect disease dynamics and the time scale of host population dynamics, highlights the importance of accounting for the potential delay in the effects of deploying public health strategies on long-term disease incidence. We find that for systems at the disease-endemic equilibrium, even
Predictive vector quantization using a neural network approach
Mohsenian, Nader; Rizvi, Syed A.; Nasrabadi, Nasser M.
1993-07-01
A new predictive vector quantization (PVQ) technique capable of exploring the nonlinear dependencies in addition to the linear dependencies that exist between adjacent blocks (vectors) of pixels is introduced. The two components of the PVQ scheme, the vector predictor and the vector quantizer, are implemented by two different classes of neural networks. A multilayer perceptron is used for the predictive component and Kohonen self- organizing feature maps are used to design the codebook for the vector quantizer. The multilayer perceptron uses the nonlinearity condition associated with its processing units to perform a nonlinear vector prediction. The second component of the PVQ scheme vector quantizers the residual vector that is formed by subtracting the output of the perceptron from the original input vector. The joint-optimization task of designing the two components of the PVQ scheme is also achieved. Simulation results are presented for still images with high visual quality.
Constructions of Vector-Valued Filters and Vector-Valued Wavelets
Directory of Open Access Journals (Sweden)
Jianxun He
2012-01-01
Full Text Available Let a =(a1,a2,…,am∈ℂm be an m-dimensional vector. Then, it can be identified with an m×m circulant matrix. By using the theory of matrix-valued wavelet analysis (Walden and Serroukh, 2002, we discuss the vector-valued multiresolution analysis. Also, we derive several different designs of finite length of vector-valued filters. The corresponding scaling functions and wavelet functions are given. Specially, we deal with the construction of filters on symmetric matrix-valued functions space.
Testing for vector autoregressive dynamics under heteroskedasticity
C.M. Hafner (Christian); H. Herwartz
2002-01-01
textabstractIn this paper we introduce a bootstrap procedure to test parameter restrictions in vector autoregressive models which is robust in cases of conditionally heteroskedastic error terms. The adopted wild bootstrap method does not require any parametric specification of the volatility process
Bayesian Vector Autoregressions with Stochastic Volatility
Uhlig, H.F.H.V.S.
1996-01-01
This paper proposes a Bayesian approach to a vector autoregression with stochastic volatility, where the multiplicative evolution of the precision matrix is driven by a multivariate beta variate.Exact updating formulas are given to the nonlinear filtering of the precision matrix.Estimation of the au
Efficient Multiplicative Updates for Support Vector Machines
DEFF Research Database (Denmark)
Potluru, Vamsi K.; Plis, Sergie N; Mørup, Morten
2009-01-01
The dual formulation of the support vector machine (SVM) objective function is an instance of a nonnegative quadratic programming problem. We reformulate the SVM objective function as a matrix factorization problem which establishes a connection with the regularized nonnegative matrix factorization...
Studies of Solar Vector Magnetic Field
Institute of Scientific and Technical Information of China (English)
WANG Jingxiu
2011-01-01
In this article, we report a few advances in the studies based on the solar vector magnetic field observations which were carried out mainly with the Solar Magnetic Field Telescope at the Huairou Solar Observing Station in the 1990s. （1） We developed necessary methodology and concepts in vector magnetogram analysis （Wang et al. 1996）. For the first time, we proposed to use the photospheric free magnetic energy to quantify the major flare productivity of solar active regions （ARs）, and it had been proved to be the best parameter in representing the major flare activity. （2） We revealed that there was always a dominant sense of magnetic shear in a given AR （Wang 1994）, which was taken as the premise of the helicity calculation in ARs; we made the first quantitative estimation of magnetic helicity evolution in ARs （Wang 1996）. （3） We identified the first group of evidence of magnetic reconnection in the lower solar atmosphere with vector magnetic field observations and proposed a two-step reconnection flare model to interpret the observed association of flux cancellation and flares （Wang and Shi 1993）. Efforts to quantify the major flare productivity of super active regions with vector magnetic field observations have been also taken.
Weighted Twin Support Vector Machine with Universum
Directory of Open Access Journals (Sweden)
Shuxia Lu
Full Text Available Universum is a new concept proposed recently, which is defined to be the sample that does not belong to any classes concerned. Support Vector Machine with Universum (..-SVM is a new algorithm, which can exploit Universum samples to improve the classifica ...
Novel cloning vectors for Bacillus thuringiensis.
Baum, J A; Coyle, D M; Gilbert, M P; Jany, C S; Gawron-Burke, C
1990-11-01
Seven replication origins from resident plasmids of Bacillus thuringienis subsp. kurstaki HD263 and HD73 were cloned in Escherichia coli. Three of these replication origins, originating from plasmids of 43, 44, and 60 MDa, were used to construct a set of compatible shuttle vectors that exhibit structural and segregational stability in the Cry- strain B. thuringiensis HD73-26. These shuttle vectors, pEG597, pEG853, and pEG854, were designed with rare restriction sites that permit various adaptations, including the construction of small recombinant plasmids lacking antibiotic resistance genes. The cryIA(c) and cryIIA insecticidal crystal protein genes were inserted into these vectors to demonstrate crystal protein production in B. thuringiensis. Introduction of a cloned cryIA(c) gene from strain HD263 into a B. thuringiensis subsp. aizawai strain exhibiting good insecticidal activity against Spodoptera exigua resulted in a recombinant strain with an improved spectrum of insecticidal activity. Shuttle vectors of this sort should be valuable in future genetic studies of B. thuringiensis as well as in the development of B. thuringiensis strains for use as microbial pesticides.
Global traffic and disease vector dispersal.
Tatem, Andrew J; Hay, Simon I; Rogers, David J
2006-04-18
The expansion of global air travel and seaborne trade overcomes geographic barriers to insect disease vectors, enabling them to move great distances in short periods of time. Here we apply a coupled human-environment framework to describe the historical spread of Aedes albopictus, a competent mosquito vector of 22 arboviruses in the laboratory. We contrast this dispersal with the relatively unchanged distribution of Anopheles gambiae and examine possible future movements of this malaria vector. We use a comprehensive database of international ship and aircraft traffic movements, combined with climatic information, to remap the global transportation network in terms of disease vector suitability and accessibility. The expansion of the range of Ae. albopictus proved to be surprisingly predictable using this combination of climate and traffic data. Traffic volumes were more than twice as high on shipping routes running from the historical distribution of Ae. albopictus to ports where it has established in comparison with routes to climatically similar ports where it has yet to invade. In contrast, An. gambiae has rarely spread from Africa, which we suggest is partly due to the low volume of sea traffic from the continent and, until very recently, a European destination for most flights.
MHD thrust vectoring of a rocket engine
Labaune, Julien; Packan, Denis; Tholin, Fabien; Chemartin, Laurent; Stillace, Thierry; Masson, Frederic
2016-09-01
In this work, the possibility to use MagnetoHydroDynamics (MHD) to vectorize the thrust of a solid propellant rocket engine exhaust is investigated. Using a magnetic field for vectoring offers a mass gain and a reusability advantage compared to standard gimbaled, elastomer-joint systems. Analytical and numerical models were used to evaluate the flow deviation with a 1 Tesla magnetic field inside the nozzle. The fluid flow in the resistive MHD approximation is calculated using the KRONOS code from ONERA, coupling the hypersonic CFD platform CEDRE and the electrical code SATURNE from EDF. A critical parameter of these simulations is the electrical conductivity, which was evaluated using a set of equilibrium calculations with 25 species. Two models were used: local thermodynamic equilibrium and frozen flow. In both cases, chlorine captures a large fraction of free electrons, limiting the electrical conductivity to a value inadequate for thrust vectoring applications. However, when using chlorine-free propergols with 1% in mass of alkali, an MHD thrust vectoring of several degrees was obtained.
The Higher Spin/Vector Model Duality
Giombi, Simone; Yin, Xi
2012-01-01
This paper is mainly a review of the dualities between Vasiliev's higher spin gauge theories in AdS4 and three dimensional large N vector models, with focus on the holographic calculation of correlation functions of higher spin currents. We also present some new results in the computation of parity odd structures in the three point functions in parity violating Vasiliev theories.
Oracle Inequalities for High Dimensional Vector Autoregressions
DEFF Research Database (Denmark)
Callot, Laurent; Kock, Anders Bredahl
This paper establishes non-asymptotic oracle inequalities for the prediction error and estimation accuracy of the LASSO in stationary vector autoregressive models. These inequalities are used to establish consistency of the LASSO even when the number of parameters is of a much larger order...
Ecology of parasite-vector interactions
Takken, W.; Koenraadt, C.J.M.
2013-01-01
Vector-borne diseases continue to be one of the most important determinants affecting human and animal health. Large numbers of people suffer from diseases like malaria, dengue, filariasis and leishmaniasis, especially in the tropics. Whereas these diseases were eradicated from the temperate climate
Vector Potential, Electromagnetic Induction and "Physical Meaning"
Giuliani, G.
2010-01-01
A forgotten experiment by Andre Blondel (1914) proves, as held on the basis of theoretical arguments in a previous paper, that the time variation of the magnetic flux is not the cause of the induced emf; the physical agent is instead the vector potential through the term [equation omitted] (when the induced circuit is at rest). The "good…
Anomalous effective lagrangians and vector resonance models
Pallante, E.; Petronzio, R.
1993-01-01
Chiral lagrangians including vector resonances have been shown to saturate the finite part of some of the counterterms needed to regularize ordinary one-loop effective lagrangians of pseudoscalar interactions with external currents. The equivalence between different models has been discussed in the
Teaching Universal Gravitation with Vector Games
Lowry, Matthew
2008-01-01
Like many high school and college physics teachers, I have found playing vector games to be a useful way of illustrating the concepts of inertia, velocity, and acceleration. Like many, I have also had difficulty in trying to get students to understand Newton's law of universal gravitation, specifically the inverse-square law and its application to…
Students' Difficulties with Vector Calculus in Electrodynamics
Bollen, Laurens; van Kampen, Paul; De Cock, Mieke
2015-01-01
Understanding Maxwell's equations in differential form is of great importance when studying the electrodynamic phenomena discussed in advanced electromagnetism courses. It is therefore necessary that students master the use of vector calculus in physical situations. In this light we investigated the difficulties second year students at KU Leuven…
Vector Product and an Integrable Dynamical System
Institute of Scientific and Technical Information of China (English)
Willi-Hans Steeb; Yorick Hardy; Igor Tanski
2011-01-01
We study an autonomous system of first order ordinary differential equations based on the vector product. We show that the system is completely integrable by constructing the first integrals. The connection with Nambu mechanics is established. The extension to higher dimensions is also discussed.
A review of learning vector quantization classifiers
Nova, David
2015-01-01
In this work we present a review of the state of the art of Learning Vector Quantization (LVQ) classifiers. A taxonomy is proposed which integrates the most relevant LVQ approaches to date. The main concepts associated with modern LVQ approaches are defined. A comparison is made among eleven LVQ classifiers using one real-world and two artificial datasets.
$h$-vectors of small matroid complexes
DeLoera, Jesus; Klee, Steven
2011-01-01
Stanley conjectured in 1977 that the $h$-vector of a matroid simplicial complex is a pure $O$-sequence. We give simple constructive proofs that the conjecture is true for matroids of rank less than or equal to 3, and corank 2. We used computers to verify that Stanley's conjecture holds for all matroids on at most nine elements.
Quantitative Measurements using Ultrasound Vector Flow Imaging
DEFF Research Database (Denmark)
Jensen, Jørgen Arendt
2016-01-01
Duplex Vector Flow Imaging (VFI) imaging is introduced as a replacement for spectral Doppler, as it automatically can yield fully quantitative flow estimates without angle correction. Continuous VFI data over 9 s for 10 pulse cycles were acquired by a 3 MHz convex probe connected to the SARUS sca...
Virtual Vector Machine for Bayesian Online Classification
Minka, Thomas P; Yuan,; Qi,
2012-01-01
In a typical online learning scenario, a learner is required to process a large data stream using a small memory buffer. Such a requirement is usually in conflict with a learner's primary pursuit of prediction accuracy. To address this dilemma, we introduce a novel Bayesian online classi cation algorithm, called the Virtual Vector Machine. The virtual vector machine allows you to smoothly trade-off prediction accuracy with memory size. The virtual vector machine summarizes the information contained in the preceding data stream by a Gaussian distribution over the classi cation weights plus a constant number of virtual data points. The virtual data points are designed to add extra non-Gaussian information about the classi cation weights. To maintain the constant number of virtual points, the virtual vector machine adds the current real data point into the virtual point set, merges two most similar virtual points into a new virtual point or deletes a virtual point that is far from the decision boundary. The info...
Use of vectors in sequence analysis.
Ishikawa, T; Yamamoto, K; Yoshikura, H
1987-10-01
Applications of the vector diagram, a new type of representation of protein structure, in homology search of various proteins including oncogene products are presented. The method takes account of various kinds of information concerning the properties of amino acids, such as Chou and Fasman's probability data. The method can detect conformational similarities of proteins which may not be detected by the conventional programs.
Angry Birds Mathematics: Parabolas and Vectors
Lamb, John H.
2013-01-01
John Lamb, a professor of mathematics education and a teacher of high school precalculus, describes how he developed a way to use the elements of the game Angry Birds® as a platform to engage his students with the concepts of parabolas and vectors. The game could be categorized as a type of microworld game in which students interact with the…
η-Invariant and Flat Vector Bundles
Institute of Scientific and Technical Information of China (English)
无
2006-01-01
We present an alternate definition of the mod Z component of the AtiyahPatodi-Singer η invariant associated to (not necessary unitary) fiat vector bundles, which identifies explicitly its real and imaginary parts. This is done by combining a deformation of flat connections introduced in a previous paper with the analytic continuation procedure appearing in the original article of Atiyah, Parodi and Singer.
Generalized Derivative Based Kernelized Learning Vector Quantization
Schleif, Frank-Michael; Villmann, Thomas; Hammer, Barbara; Schneider, Petra; Biehl, Michael; Fyfe, Colin; Tino, Peter; Charles, Darryl; Garcia-Osoro, Cesar; Yin, Hujun
2010-01-01
We derive a novel derivative based version of kernelized Generalized Learning Vector Quantization (KGLVQ) as an effective, easy to interpret, prototype based and kernelized classifier. It is called D-KGLVQ and we provide generalization error bounds, experimental results on real world data, showing t
Malaria vector control: current and future strategies
Takken, W.; Knols, B.G.J.
2009-01-01
The recently announced call for malaria eradication represents a new page in the history of this disease. This has been triggered by remarkable reductions in malaria resulting from combined application of effective drugs and vector control. However, this strategy is threatened by development of inse
Isotropy theorem for cosmological vector fields
Cembranos, J A R; Maroto, A L; Jareño, S J Núñez
2012-01-01
We consider homogeneous abelian vector fields in an expanding universe. We find a mechanical analogy in which the system behaves as a particle moving in three dimensions under the action of a central potential. In the case of bounded and rapid evolution compared to the rate of expansion, we show by making use of the virial theorem that for arbitrary potential and polarization pattern, the average energy-momentum tensor is always diagonal and isotropic despite the intrinsic anisotropic evolution of the vector field. For simple power-law potentials of the form V=\\lambda (A^\\mu A_\\mu)^n, the average equation of state is found to be w=(n-1)/(n+1). This implies that vector coherent oscillations could act as natural dark matter or dark energy candidates. Finally, we show that under very general conditions, the average energy-momentum tensor of a rapidly evolving bounded vector field in any background geometry is always isotropic and has the perfect fluid form for any locally inertial observer.
Linearization of germs of hyperbolic vector fields
Bonckaert, P; Naudot, [No Value; Yang, JZ
2003-01-01
We develop a normal form to express asymptotically a conjugacy between a germ of resonant vector field and its linear part. We show that such an asymptotic expression can be written in terms of functions of the Logarithmic Mourtada type. To cite this article: P Bonckaert et al., C. R. Acad. Sci. Par
Symmetries of Elko and massive vector fields
Lee, Cheng-Yang
2013-01-01
This thesis studies the symmetries and phenomenologies of the massive vector fields of indefinite spin with both scalar and spin-one degrees of freedom and Elko. The investigation is conducted by using and extending the quantum field theory formalism developed by Wigner and Weinberg. In particular, we explore the possibility that the $W^{\\pm}$ and $Z$ bosons have an additional scalar degree of freedom and show that Elko is a fermionic dark matter candidate. We show that the massive vector fields of indefinite spin are consistent with Poincar\\'{e} symmetry and have physically desirable properties that are absent for their pure spin-one counterpart. Using the new vector fields, the decay of the $W^{\\pm}$ and $Z$ bosons to leptons at tree-level are in agreement with the Standard Model (SM) predictions. For higher order scattering amplitudes, the theory has better convergent behaviour than the intermediate vector boson model and the Fermi theory. Elko has the unusual property that it satisfies the Klein-Gordon bu...
Demonstration of a Vector Velocity Technique
DEFF Research Database (Denmark)
Hansen, Peter Møller; Pedersen, Mads M.; Hansen, Kristoffer L.;
2011-01-01
With conventional Doppler ultrasound it is not possible to estimate direction and velocity of blood flow, when the angle of insonation exceeds 60–70°. Transverse oscillation is an angle independent vector velocity technique which is now implemented on a conventional ultrasound scanner. In this pa...
Image compression using address-vector quantization
Nasrabadi, Nasser M.; Feng, Yushu
1990-12-01
A novel vector quantization scheme, the address-vector quantizer (A-VQ), is proposed which exploits the interblock correlation by encoding a group of blocks together using an address-codebook (AC). The AC is a set of address-codevectors (ACVs), each representing a combination of addresses or indices. Each element of the ACV is an address of an entry in the LBG-codebook, representing a vector-quantized block. The AC consists of an active (addressable) region and an inactive (nonaddressable) region. During encoding the ACVs in the AC are reordered adaptively to bring the most probable ACVs into the active region. When encoding an ACV, the active region is checked, and if such an address combination exists, its index is transmitted to the receiver. Otherwise, the address of each block is transmitted individually. The SNR of the images encoded by the A-VQ method is the same as that of a memoryless vector quantizer, but the bit rate is by a factor of approximately two.
Vector Volume Flow in Arteriovenous Fistulas
DEFF Research Database (Denmark)
Hansen, Peter Møller; Heerwagen, Søren; Pedersen, Mads Møller;
2013-01-01
, but is very challenging due to the angle dependency of the Doppler technique and the anatomy of the fistula. The angle independent vector ultrasound technique Transverse Oscillation provides a new and more intuitive way to measure volume flow in an arteriovenous fistula. In this paper the Transverse...
The Integration Order of Vector Autoregressive Processes
DEFF Research Database (Denmark)
Franchi, Massimo
We show that the order of integration of a vector autoregressive process is equal to the difference between the multiplicity of the unit root in the characteristic equation and the multiplicity of the unit root in the adjoint matrix polynomial. The equivalence with the standard I(1) and I(2...
An Improved Support Vector Machines： NNSVM
Institute of Scientific and Technical Information of China (English)
LIHonglian; WANGChunhua; YUANBaozong
2004-01-01
In this paper we propose an improved support vector machine: NNSVM. It first prunes the training set, reserves or deletes a sample according to whether its nearest neighbor has same class label with itself or not,then trains the new set with standard SVM to obtain a classifier. Experimental results show that NNSVM is better than SVM in speed and accuracy of classiflcation.
Polynomial Vector Fields in One Complex Variable
DEFF Research Database (Denmark)
Branner, Bodil
In recent years Adrien Douady was interested in polynomial vector fields, both in relation to iteration theory and as a topic on their own. This talk is based on his work with Pierrette Sentenac, work of Xavier Buff and Tan Lei, and my own joint work with Kealey Dias....
Perturbations of ultralight vector field dark matter
Cembranos, J A R; Jareño, S J Núñez
2016-01-01
We study the dynamics of cosmological perturbations in models of dark matter based on ultralight coherent vector fields. Very much as for scalar field dark matter, we find two different regimes in the evolution: for modes with $k^2\\ll {\\cal H}ma$, we have a particle-like behaviour indistinguishable from cold dark matter, whereas for modes with $k^2\\gg {\\cal H}ma$, we get a wave-like behaviour in which the sound speed is non-vanishing and of order $c_s^2\\simeq k^2/m^2a^2$. This implies that, also in these models, structure formation could be suppressed on small scales. However, unlike the scalar case, the fact that the background evolution contains a non-vanishing homogeneous vector field implies that, in general, the evolution of the three kinds of perturbations (scalar, vector and tensor) can no longer be decoupled at the linear level. More specifically, in the particle regime, the three types of perturbations are actually decoupled, whereas in the wave regime, the three vector field perturbations generate o...
[Conflicts and vector-borne diseases
DEFF Research Database (Denmark)
Bygbjerg, Ib Christian
2010-01-01
not available for most diseases. Promising preventive methods, including long-lasting impregnated bed-nets and tents, are available. War has been an impetus for disclosing life-cycles of vector-borne diseases and for control methods; peace, reconciliation and poverty reduction are required to achieve lasting...
Bethe vectors for XXX-spin chain
Burdík, Čestmír; Fuksa, Jan; Isaev, Alexei
2014-11-01
The paper deals with algebraic Bethe ansatz for XXX-spin chain. Generators of Yang-Baxter algebra are expressed in basis of free fermions and used to calculate explicit form of Bethe vectors. Their relation to N-component models is used to prove conjecture about their form in general. Some remarks on inhomogeneous XXX-spin chain are included.
Risk based surveillance for vector borne diseases
DEFF Research Database (Denmark)
Bødker, Rene
of samples and hence early detection of outbreaks. Models for vector borne diseases in Denmark have demonstrated dramatic variation in outbreak risk during the season and between years. The Danish VetMap project aims to make these risk based surveillance estimates available on the veterinarians smart phones...
High performance computing on vector systems
Roller, Sabine
2008-01-01
Presents the developments in high-performance computing and simulation on modern supercomputer architectures. This book covers trends in hardware and software development in general and specifically the vector-based systems and heterogeneous architectures. It presents innovative fields like coupled multi-physics or multi-scale simulations.
A Lesson in Vectors "Plain" and Simple
Bradshaw, David M.
2004-01-01
The United States Military Academy (USMA) has a four course core mathematics curriculum that is studied by all students. The third course is MA205, Calculus II; a multivariate calculus course filled with practical applications. During a Problem Solving Lab (PSL), students participated in a hands-on exercise with multiple vector operations,…
Robustifying Descriptor Instability using Fisher Vectors
I. Everts; J.C. van Gemert; T. Mensink; T. Gevers
2014-01-01
Many computer vision applications, including image classification, matching, and retrieval use global image representations, such as the Fisher vector, to encode a set of local image patches. To describe these patches, many local descriptors have been designed to be robust against lighting changes a
Mosquito Oviposition Behavior and Vector Control
Directory of Open Access Journals (Sweden)
Jonathan F. Day
2016-11-01
Full Text Available The burden of gene transfer from one mosquito generation to the next falls on the female and her eggs. The selection of an oviposition site that guarantees egg and larval survival is a critical step in the reproductive process. The dangers associated with ephemeral aquatic habitats, lengthy droughts, freezing winters, and the absence of larval nutrition makes careful oviposition site selection by a female mosquito extremely important. Mosquito species exhibit a remarkable diversity of oviposition behaviors that ensure eggs are deposited into microenvironments conducive for successful larval development and the emergence of the next mosquito generation. An understanding of mosquito oviposition behavior is necessary for the development of surveillance and control opportunities directed against specific disease vectors. For example, Aedes aegypti Linnaeus is the vector of viruses causing important human diseases including yellow fever, dengue, chikungunya, and Zika. The preference of this species to oviposit in natural and artificial containers has facilitated the development of Ae. aegypti-specific surveillance and toxic oviposition traps designed to detect and control this important vector species in and around disease foci. A better understanding of the wide diversity of mosquito oviposition behavior will allow the development of new and innovative surveillance and control devices directed against other important mosquito vectors of human and animal disease.
Vector boson pair production at hadron colliders
Adamson, K L
2002-01-01
We calculate the contribution of gluon-gluon induced processes to vector boson pair production at hadron colliders, specifically the production of WZ, W gamma and Z gamma pairs. We calculate the tree level processes gg -> WZqq-bqr, gg -> W gamma qq-bar and gg -> Z gamma qq-bar, and the one loop process gg -> Z gamma. We use the helicity method and include the decay of the W and Z bosons into leptons in the narrow width approximation. We include anomalous triple gauge couplings in all of our vector boson pair production calculations. In order to integrate over the qq-bar final state phase space we use an extended version of the subtraction method to NNLO and cancel collinear singularities explicitly. The general subtraction terms that are obtained apply to all vector boson pair production processes. Due to the large gluon density at low x, the gluon induced terms of vector boson pair production are expected to be the dominant NNLO QCD correction, relevant at LHC energies. However, we show that due to a cancell...
Comparison between covariant and orthogonal Lyapunov vectors.
Yang, Hong-liu; Radons, Günter
2010-10-01
Two sets of vectors, covariant Lyapunov vectors (CLVs) and orthogonal Lyapunov vectors (OLVs), are currently used to characterize the linear stability of chaotic systems. A comparison is made to show their similarity and difference, especially with respect to the influence on hydrodynamic Lyapunov modes (HLMs). Our numerical simulations show that in both Hamiltonian and dissipative systems HLMs formerly detected via OLVs survive if CLVs are used instead. Moreover, the previous classification of two universality classes works for CLVs as well, i.e., the dispersion relation is linear for Hamiltonian systems and quadratic for dissipative systems, respectively. The significance of HLMs changes in different ways for Hamiltonian and dissipative systems with the replacement of OLVs with CLVs. For general dissipative systems with nonhyperbolic dynamics the long-wavelength structure in Lyapunov vectors corresponding to near-zero Lyapunov exponents is strongly reduced if CLVs are used instead, whereas for highly hyperbolic dissipative systems the significance of HLMs is nearly identical for CLVs and OLVs. In contrast the HLM significance of Hamiltonian systems is always comparable for CLVs and OLVs irrespective of hyperbolicity. We also find that in Hamiltonian systems different symmetry relations between conjugate pairs are observed for CLVs and OLVs. Especially, CLVs in a conjugate pair are statistically indistinguishable in consequence of the microreversibility of Hamiltonian systems. Transformation properties of Lyapunov exponents, CLVs, and hyperbolicity under changes of coordinate are discussed in appendices.
Internal mode of incoherent photovoltaic vector solitons
Institute of Scientific and Technical Information of China (English)
Zhang Bing-Zhi; Wang Hong-Cheng; She Wei-Long
2007-01-01
The internal modes of incoherent vector solitons (IVSs) in photovoltaic photorefractive materials are investigated in the framework of coupled nonlinear Schr(o)dinger equations. It is found that there is a pair of internal modes corresponding to a bright-bright IVS. The propagation dynamics of the bright-bright IVS perturbed by the internal modes is simulated by numerical method.
VECTORS OF MALARIA AND FILARIASIS IN INDONESIA
Directory of Open Access Journals (Sweden)
Hoedojo Hoedojo
2012-09-01
Full Text Available Malaria at present is still one of the important mosquito-borne diseases in Indonesia. The disease is widespread all over the country and involves nearly all islands. Sixteen Anopheles species have been reconfirmed as malaria vectors. They were distributed geographically as follows: Coastal areas and lagoons ------------------------------------- An sundaicus and An.subpictus Cultivated ricefields and swampy areas -------------------- An.aconitus, An.barbirostris, An.nigerrimus and An.sinensis Forest inland areas in shaded temporary pools, muddy animal wallows and hoof-prints -------------------------------------------------------- An.balabacensis, An.bancrofti, An.farauti, An.koliensis and An.punctulatus Swamp forest edge in ditches with vegeta- ---------------- An.letifer and An.ludlowae don Hilly areas in seepages, streams and clear moving water ---------------------------------------------- Anflavirostris, An.maculatus and Anminimus. The species (of most general importance is An.sundaicus, which is restricted by its preference for brackish water and is prevalent in coastal areas of Java. Their types in behaviour of An.sundaicus appear as follows : 1. An.sundaicus in South Coast of Java in general. This species is essentially anthropophilic, exophagic and rests outdoor. It shows susceptible to DDT. 2. An.sundaicus in Cilacap, Central Java. This mosquito is a pure anthropophilic form. It bites man in houses and outdoors, rests indoors and is known resistant to DDT. 3. An.sundaicus in Yogyakarta and Purworejo, Central Java. This mosquito is a strong zoophilic species. It rests and prefers to bite outdoors and shows tolerance to DDT. Human filariasis in Indonesia is the result of infection by three endemic species, namely, Wuchereria bancrofti, Brugia malayi, and Brugia timori.W.bancrofti infection is found in both urban and rural areas. Twenty species of mosquitoes are confirmed as filariasis vectors. The urban type bancroftian filariasis
Chromatography purification of canine adenoviral vectors.
Segura, María Mercedes; Puig, Meritxell; Monfar, Mercè; Chillón, Miguel
2012-06-01
Canine adenovirus vectors (CAV2) are currently being evaluated for gene therapy, oncolytic virotherapy, and as vectors for recombinant vaccines. Despite the need for increasing volumes of purified CAV2 preparations for preclinical and clinical testing, their purification still relies on the use of conventional, scale-limited CsCl ultracentrifugation techniques. A complete downstream processing strategy for CAV2 vectors based on membrane filtration and chromatography is reported here. Microfiltration and ultra/diafiltration are selected for clarification and concentration of crude viral stocks containing both intracellular and extracellular CAV2 particles. A DNase digestion step is introduced between ultrafiltration and diafiltration operations. At these early stages, concentration of vector stocks with good recovery of viral particles (above 80%) and removal of a substantial amount of protein and nucleic acid contaminants is achieved. The ability of various chromatography techniques to isolate CAV2 particles was evaluated. Hydrophobic interaction chromatography using a Fractogel propyl tentacle resin was selected as a first chromatography step, because it allows removal of the bulk of contaminating proteins with high CAV2 yields (88%). An anion-exchange chromatography step using monolithic supports is further introduced to remove the remaining contaminants with good recovery of CAV2 particles (58-69%). The main CAV2 viral structural components are visualized in purified preparations by electrophoresis analyses. Purified vector stocks contained intact icosahedral viral particles, low contamination with empty viral capsids (10%), and an acceptable total-to-infectious particle ratio (below 30). The downstream processing strategy that was developed allows preparation of large volumes of high-quality CAV2 stocks.
Perturbations of ultralight vector field dark matter
Cembranos, J. A. R.; Maroto, A. L.; Núñez Jareño, S. J.
2017-02-01
We study the dynamics of cosmological perturbations in models of dark matter based on ultralight coherent vector fields. Very much as for scalar field dark matter, we find two different regimes in the evolution: for modes with {k}^2≪ Hma, we have a particle-like behaviour indistinguishable from cold dark matter, whereas for modes with {k}^2≫ Hma, we get a wave-like behaviour in which the sound speed is non-vanishing and of order c s 2 ≃ k 2/ m 2 a 2. This implies that, also in these models, structure formation could be suppressed on small scales. However, unlike the scalar case, the fact that the background evolution contains a non-vanishing homogeneous vector field implies that, in general, the evolution of the three kinds of perturbations (scalar, vector and tensor) can no longer be decoupled at the linear level. More specifically, in the particle regime, the three types of perturbations are actually decoupled, whereas in the wave regime, the three vector field perturbations generate one scalar-tensor and two vector-tensor perturbations in the metric. Also in the wave regime, we find that a non-vanishing anisotropic stress is present in the perturbed energy-momentum tensor giving rise to a gravitational slip of order ( Φ - Ψ)/ Φ ˜ c s 2 . Moreover in this regime the amplitude of the tensor to scalar ratio of the scalar-tensor modes is also h/ Φ ˜ c s 2 . This implies that small-scale density perturbations are necessarily associated to the presence of gravity waves in this model. We compare their spectrum with the sensitivity of present and future gravity waves detectors.
Vector Modulator for Phase Shifting in Passive Beamforming Wireless Systems
Directory of Open Access Journals (Sweden)
P.Sampath,
2010-05-01
Full Text Available This paper proposes vector modulator for changing the phase of a signal in passive beamforming system. Vector modulator is used to perform a phase shift function with added benefit of amplitude control. It is used to improve the directivity of RF waves in Wireless systems. Vector modulator is implemented for a center frequency of 902.5 MHz. The simulation is performed for individual blocks of the vector modulator and for vector modulator with JFET and MOSFET as controlling device in the variable attenuator of the vector modulator.
Construction of Yeast Vectors with Resistance to Geneticin
Institute of Scientific and Technical Information of China (English)
林会兰; 张广; 周全; 陈国强
2002-01-01
Two Escherichia coli-Saccharomyces cerevisiae shuttle vectors containing a resistance marker to geneticin (G418) are constructed. Both vectors contain a kanamycin-resistant marker (KanMX4) module coding aminoglycoside 3'-phosphotransferase (APH) that renders E. coli resistant to kanamycin and S. cerevisiae to geneticin. These vectors overcome the shortage of the conventional yeast vectors bearing HIS3, TRP1, LEU2, and URA3 modules as selection markers, which require hosts to be auxotrophic. Green fluorescent protein (GFP) is used as the reporter to examine the functions of the vectors. The vectors are powerful tools for the convenient cloning and controlled expression of genes in most S. cerevisiae strains.
Vectors a Fortran 90 module for 3-dimensional vector and dyadic arithmetic
Energy Technology Data Exchange (ETDEWEB)
Brock, B.C.
1998-02-01
A major advance contained in the new Fortran 90 language standard is the ability to define new data types and the operators associated with them. Writing computer code to implement computations with real and complex three-dimensional vectors and dyadics is greatly simplified if the equations can be implemented directly, without the need to code the vector arithmetic explicitly. The Fortran 90 module described here defines new data types for real and complex 3-dimensional vectors and dyadics, along with the common operations needed to work with these objects. Routines to allow convenient initialization and output of the new types are also included. In keeping with the philosophy of data abstraction, the details of the implementation of the data types are maintained private, and the functions and operators are made generic to simplify the combining of real, complex, single- and double-precision vectors and dyadics.
Directory of Open Access Journals (Sweden)
Liu Qing-you
2011-01-01
Full Text Available Abstract In this paper, a scalarization result of ε-weak efficient solution for a vector equilibrium problem (VEP is given. Using this scalarization result, the connectedness of ε-weak efficient and ε-efficient solutions sets for the VEPs are proved under some suitable conditions in real Hausdorff topological vector spaces. The main results presented in this paper improve and generalize some known results in the literature.
Vector and axial vector mesons in a nonlocal chiral quark model
Villafañe, M F Izzo; Scoccola, N N
2016-01-01
Basic features of nonstrange vector and axial vector mesons are analyzed in the framework of a chiral quark model that includes nonlocal four fermion couplings. Unknown model parameters are determined from some input values of masses and decay constants, while nonlocal form factors are taken from a fit to lattice QCD results for effective quark propagators. Numerical results show a good agreement with the observed meson phenomenology.
Charmless Hadronic B Decays into Vector, Axial Vector and Tensor Final States at BaBar
Energy Technology Data Exchange (ETDEWEB)
Gandini, Paolo; /Milan U. /INFN, Milan
2012-04-06
We present experimental measurements of branching fraction and longitudinal polarization fraction in charmless hadronic B decays into vector, axial vector and tensor final states with the final dataset of BABAR. Measurements of such kind of decays are a powerful tool both to test the Standard Model and search possible sources of new physics. In this document we present a short review of the last experimental results at BABAR concerning charmless quasi two-body decays in final states containing particles with spin 1 or spin 2 and different parities. This kind of decays has received considerable theoretical interest in the last few years and this particular attention has led to interesting experimental results at the current b-factories. In fact, the study of longitudinal polarization fraction f{sub L} in charmless B decays to vector vector (VV), vector axial-vector (VA) and axial-vector axial-vector (AA) mesons provides information on the underlying helicity structure of the decay mechanism. Naive helicity conservation arguments predict a dominant longitudinal polarization fraction f{sub L} {approx} 1 for both tree and penguin dominated decays and this pattern seems to be confirmed by tree-dominated B {yields} {rho}{rho} and B{sup +} {yields} {Omega}{rho}{sup +} decays. Other penguin dominated decays, instead, show a different behavior: the measured value of f{sub L} {approx} 0.5 in B {yields} {phi}K* decays is in contrast with naive Standard Model (SM) calculations. Several solutions have been proposed such as the introduction of non-factorizable terms and penguin-annihilation amplitudes, while other explanations invoke new physics. New modes have been investigated to shed more light on the problem.
Dispersive approach to QCD: tau lepton hadronic decay in vector and axial-vector channels
Nesterenko, A V
2014-01-01
The dispersive approach to QCD, which extends the applicability range of perturbation theory towards the infrared domain, is developed. This approach properly accounts for the intrinsically nonperturbative constraints, which originate in the low-energy kinematic restrictions on pertinent strong interaction processes. The dispersive approach proves to be capable of describing OPAL (update 2012) and ALEPH (update 2014) experimental data on inclusive tau lepton hadronic decay in vector and axial-vector channels in a self-consistent way.
Vector and axial vector mesons in a nonlocal chiral quark model
Izzo Villafañe, M. F.; Gómez Dumm, D.; Scoccola, N. N.
2016-09-01
Basic features of nonstrange vector and axial vector mesons are analyzed in the framework of a chiral quark model that includes nonlocal four-fermion couplings. Unknown model parameters are determined from some input values of masses and decay constants, while nonlocal form factors are taken from a fit to lattice QCD results for effective quark propagators. Numerical results show a good agreement with the observed meson phenomenology.
Vector adaptive predictive coder for speech and audio
Chen, Juin-Hwey (Inventor); Gersho, Allen (Inventor)
1990-01-01
A real-time vector adaptive predictive coder which approximates each vector of K speech samples by using each of M fixed vectors in a first codebook to excite a time-varying synthesis filter and picking the vector that minimizes distortion. Predictive analysis for each frame determines parameters used for computing from vectors in the first codebook zero-state response vectors that are stored at the same address (index) in a second codebook. Encoding of input speech vectors s.sub.n is then carried out using the second codebook. When the vector that minimizes distortion is found, its index is transmitted to a decoder which has a codebook identical to the first codebook of the decoder. There the index is used to read out a vector that is used to synthesize an output speech vector s.sub.n. The parameters used in the encoder are quantized, for example by using a table, and the indices are transmitted to the decoder where they are decoded to specify transfer characteristics of filters used in producing the vector s.sub.n from the receiver codebook vector selected by the vector index transmitted.
Co-occurrence Vectors from Corpora vs. Distance Vectors from Dictionaries
Niwa, Y; Niwa, Yoshiki; Nitta, Yoshihiko
1995-01-01
A comparison was made of vectors derived by using ordinary co-occurrence statistics from large text corpora and of vectors derived by measuring the inter-word distances in dictionary definitions. The precision of word sense disambiguation by using co-occurrence vectors from the 1987 Wall Street Journal (20M total words) was higher than that by using distance vectors from the Collins English Dictionary (60K head words + 1.6M definition words). However, other experimental results suggest that distance vectors contain some different semantic information from co-occurrence vectors. From no-reply@xxx.lanl.gov Fri Nov 12 12:25 MET 1999 Received: from newmint.cern.ch (newmint.cern.ch [137.138.26.94]) by sundh98.cern.ch (8.8.5/8.8.5) with ESMTP id MAA10923 for ; Fri, 12 Nov 1999 12:25:47 +0100 (MET) Received: from uuu.lanl.gov (uuu.lanl.gov [204.121.6.59]) by newmint.cern.ch (8.9.3/8.9.3) with ESMTP id MAA18850 for ; Fri, 12 Nov 1999 12:25:46 +0100 (MET) Received: from xxx.lanl.gov (xxx.lanl.gov [204.121.6.57]) by uu...
Vector Velocity Imaging Using Cross-Correlation and Virtual Sources
DEFF Research Database (Denmark)
Holfort, Iben Kraglund; Kortbek, Jacob; Jensen, Jørgen Arendt
2006-01-01
Previous investigations have shown promising results in using the directional cross-correlation method to estimate velocity vectors. The velocity vector estimate provides information on both velocity direction and magnitude. The direction is estimated by beamforming signals along directions...
Institute of Scientific and Technical Information of China (English)
张浩然; 韩正之; 李昌刚
2002-01-01
This paper gives a introduction of the basic ideas, basic theory, key techniques, and application of the sup-port vector machine (SVM), and indicates the similarities and differences between support vector machines and neuralnetworks.
Pasting and reversing operations over some vector spaces
Acosta-Humanez, Primitivo; Chuquen, Adriana; Rodríguez, Angela
2012-01-01
Pasting and Reversing operations have been used successfully over the set of integer numbers, simple permutations, rings and recently over a generalized vector product. In this paper, these operations are defined from a natural way to be applied over vector spaces. In particular we study Pasting and Reversing over vectors, matrices and we rewrite some properties for polynomials as vector space. Finally we study some properties of Reversing through linear transformations as for example an anal...
Canine vector-borne diseases in Brazil
Directory of Open Access Journals (Sweden)
Dantas-Torres Filipe
2008-08-01
Full Text Available Abstract Canine vector-borne diseases (CVBDs are highly prevalent in Brazil and represent a challenge to veterinarians and public health workers, since some diseases are of great zoonotic potential. Dogs are affected by many protozoa (e.g., Babesia vogeli, Leishmania infantum, and Trypanosoma cruzi, bacteria (e.g., Anaplasma platys and Ehrlichia canis, and helminths (e.g., Dirofilaria immitis and Dipylidium caninum that are transmitted by a diverse range of arthropod vectors, including ticks, fleas, lice, triatomines, mosquitoes, tabanids, and phlebotomine sand flies. This article focuses on several aspects (etiology, transmission, distribution, prevalence, risk factors, diagnosis, control, prevention, and public health significance of CVBDs in Brazil and discusses research gaps to be addressed in future studies.
Lepton flavor violation with light vector bosons
Directory of Open Access Journals (Sweden)
Julian Heeck
2016-07-01
Full Text Available New sub-GeV vector bosons with couplings to muons but not electrons have been discussed in order to explain the muon's magnetic moment, the gap of high-energy neutrinos in IceCube or the proton radius puzzle. If such a light Z′ not only violates lepton universality but also lepton flavor, as expected for example from the recent hint for h→μτ at CMS, the two-body decay mode τ→μZ′ opens up and for MZ′<2mμ gives better constraints than τ→3μ already with 20-year-old ARGUS limits. We discuss the general prospects and motivation of light vector bosons with lepton-flavor-violating couplings.
Vector Meson Production in Collisions of Nucleons
Brinkmann, K.-Th.; Abdel-Bary, M.; Abdel-Samad, S.; Clement, H.; Doroshkevich, E.; Dshemuchadse, S.; Dutz, H.; Ehrhardt, K.; Erhardt, A.; Eyrich, W.; Filippi, A.; Freiesleben, H.; Fritsch, M.; Georgi, J.; Gillitzer, A.; Gonser, P.; Jäkel, R.; Karsch, L.; Kilian, K.; Koch, H.; Kreß, J.; Kuhlmann, E.; Marcello, S.; Meyer, W.; Michel, P.; Morsch, H. P.; Möller, K.; Mörtel, H.; Naumann, L.; Pinna, L.; Pizzolotto, L.; Roderburg, E.; Schamlott, A.; Schönmeier, P.; Schroeder, W.; Schulte-Wissermann, M.; Sefzick, T.; Steinke, M.; Stinzing, F.; Sun, G. Y.; Ucar, A.; Ullrich, W.; Wagner, G. J.; Wagner, M.; Wilms, A.; Wintz, P.; Wirth, S.; Wüstner, P.; Zupranski, P.
The production of vector mesons in collisions between nucleons is studied in order to address a variety of issues concerning nucleon-nucleon interaction, reaction mechanism and properties of baryons. These studies are summarized with emphasis on the most recent experiments at the Time-of-Flight spectrometer TOF and results obtained at the COoler SYnchrotron COSY in Jülich. While currently the open questions regarding the so-called OZI violation, its relation to the meson exchange picture and the relative importance of contributions to the production mechanism from various channels within this formalism are still unresolved, the present-day experiments hold the potential to clarify the situation greatly. Possible extensions of the experimental program on vector mesons using 4π detection techniques for charged as well as neutral particles, in particular π0, are discussed.
Genetically engineering adenoviral vectors for gene therapy.
Coughlan, Lynda
2014-01-01
Adenoviral (Ad) vectors are commonly used for various gene therapy applications. Significant advances in the genetic engineering of Ad vectors in recent years has highlighted their potential for the treatment of metastatic disease. There are several methods to genetically modify the Ad genome to incorporate retargeting peptides which will redirect the natural tropism of the viruses, including homologous recombination in bacteria or yeast. However, homologous recombination in yeast is highly efficient and can be achieved without the need for extensive cloning strategies. In addition, the method does not rely on the presence of unique restriction sites within the Ad genome and the reagents required for this method are widely available and inexpensive. Large plasmids containing the entire adenoviral genome (~36 kbp) can be modified within Saccharomyces cerevisiae yeast and genomes easily rescued in Escherichia coli hosts for analysis or amplification. A method for two-step homologous recombination in yeast is described in this chapter.
Dual Vector Spaces and Physical Singularities
Rowlands, Peter
Though we often refer to 3-D vector space as constructed from points, there is no mechanism from within its definition for doing this. In particular, space, on its own, cannot accommodate the singularities that we call fundamental particles. This requires a commutative combination of space as we know it with another 3-D vector space, which is dual to the first (in a physical sense). The combination of the two spaces generates a nilpotent quantum mechanics/quantum field theory, which incorporates exact supersymmetry and ultimately removes the anomalies due to self-interaction. Among the many natural consequences of the dual space formalism are half-integral spin for fermions, zitterbewegung, Berry phase and a zero norm Berwald-Moor metric for fermionic states.
Improving the lattice axial vector current
Energy Technology Data Exchange (ETDEWEB)
Horsley, R. [Edinburgh Univ. (United Kingdom). School of Physics and Astronomy; Nakamura, Y. [RIKEN Advanced Institute for Computational Science, Kobe (Japan); Perlt, H.; Schiller, A. [Leipzig Univ. (Germany). Inst. fuer Theoretische Physik; Rakow, P.E.L. [Liverpool Univ. (United Kingdom). Theoretical Physics Div.; Schierholz, G. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Zanotti, J.M. [Adelaide Univ. (Australia). CSSM, Dept. of Physics
2015-11-15
For Wilson and clover fermions traditional formulations of the axial vector current do not respect the continuum Ward identity which relates the divergence of that current to the pseudoscalar density. Here we propose to use a point-split or one-link axial vector current whose divergence exactly satisfies a lattice Ward identity, involving the pseudoscalar density and a number of irrelevant operators. We check in one-loop lattice perturbation theory with SLiNC fermion and gauge plaquette action that this is indeed the case including order O(a) effects. Including these operators the axial Ward identity remains renormalisation invariant. First preliminary results of a nonperturbative check of the Ward identity are also presented.
Generalized Toeplitz operators and cyclic vectors
Gassier, G; Zerouali, E H
2003-01-01
We give in this paper some asymptotic Von Neumann inequalities for power bounded operators in the class C subrho intersection C sub 1. and some spacial von Neumann inequalities associated with non zero elements of the point spectrum, when it is non void, of generalized Toeplitz operators. Introducing perturbed kernel, we consider classes C sub R which extend the classical classes C subrho. We give results about absolute continuity with respect to the Haar measure for operators in class C sub R intersection C sub 1. This allows us to give new results on cyclic vectors for such operators and provides invariant subspaces for their powers. Relationships between cyclic vectors for T and T* involving generalized Toeplitz operators are given and the commutativity of left brace T right brace', the commutant of T is discussed.
Application of Vector Triggering Random Decrement
DEFF Research Database (Denmark)
Asmussen, J. C.; Ibrahim, S. R.; Brincker, Rune
This paper deals with applications of the vector triggering Random Decrement technique. This technique is new and developed with the aim of minimizing estimation time and identification errors. The theory behind the technique is discussed in an accompanying paper. The results presented in this pa......This paper deals with applications of the vector triggering Random Decrement technique. This technique is new and developed with the aim of minimizing estimation time and identification errors. The theory behind the technique is discussed in an accompanying paper. The results presented...... in this paper should be regarded as a further documentation of the technique. The key point in Random Decrement estimation is the formulation of a triggering condition. If the triggering condition is fulfilled a time segment from each measurement is picked out and averaged with previous time segments. The final...
Application of Vector Triggering Random Decrement
DEFF Research Database (Denmark)
Asmussen, J. C.; Ibrahim, S. R.; Brincker, Rune
1997-01-01
This paper deals with applications of the vector triggering Random Decrement technique. This technique is new and developed with the aim of minimizing estimation time and identification errors. The theory behind the technique is discussed in an accompanying paper. The results presented in this pa......This paper deals with applications of the vector triggering Random Decrement technique. This technique is new and developed with the aim of minimizing estimation time and identification errors. The theory behind the technique is discussed in an accompanying paper. The results presented...... in this paper should be regarded as a further documentation of the technique. The key point in Random Decrement estimation is the formulation of a triggering condition. If the triggering condition is fulfilled a time segment from each measurement is picked out and averaged with previous time segments. The final...
Support vector machine for automatic pain recognition
Monwar, Md Maruf; Rezaei, Siamak
2009-02-01
Facial expressions are a key index of emotion and the interpretation of such expressions of emotion is critical to everyday social functioning. In this paper, we present an efficient video analysis technique for recognition of a specific expression, pain, from human faces. We employ an automatic face detector which detects face from the stored video frame using skin color modeling technique. For pain recognition, location and shape features of the detected faces are computed. These features are then used as inputs to a support vector machine (SVM) for classification. We compare the results with neural network based and eigenimage based automatic pain recognition systems. The experiment results indicate that using support vector machine as classifier can certainly improve the performance of automatic pain recognition system.
Bloch vector, disclination and exotic quantum holonomy
Energy Technology Data Exchange (ETDEWEB)
Tanaka, Atushi, E-mail: tanaka-atushi@tmu.ac.jp [Department of Physics, Tokyo Metropolitan University, Hachioji, Tokyo 192-0397 (Japan); Cheon, Taksu [Laboratory of Physics, Kochi University of Technology, Tosa Yamada, Kochi 782-8502 (Japan)
2015-09-04
A topological formulation of the eigenspace anholonomy, where eigenspaces are interchanged by adiabatic cycles, is introduced. The anholonomy in two-level systems is identified with a disclination of the director (headless vector) of a Bloch vector, which characterizes eigenprojectors. The covering map structure behind the exotic quantum holonomy and the role of the homotopy classification of adiabatic cycles are elucidated. The extensions of this formulation to nonadiabatic cycles and N-level systems are outlined. - Highlights: • A topological formulation of the eigenspace anholonomy is proposed. • The covering map structure behind the anholonomy is identified. • The role of homotopy classification of adiabatic cycles is explained. • The anholonomy in two-level systems is associated with disclinations. • The present formulation offers an extension to nonadiabatic cycles.
SIT for African malaria vectors: Epilogue
Directory of Open Access Journals (Sweden)
Townson Harold
2009-11-01
Full Text Available Abstract As a result of increased support and the diligent application of new and conventional anti-malaria tools, significant reductions in malaria transmission are being accomplished. Historical and current evolutionary responses of vectors and parasites to malaria interventions demonstrate that it is unwise to assume that a limited suite of tools will remain effective indefinitely, thus efforts to develop new interventions should continue. This collection of manuscripts surveys the prospects and technical challenges for applying a novel tool, the sterile insect technique (SIT, against mosquitoes that transmit malaria. The method has been very successful against many agricultural pest insects in area-wide programs, but demonstrations against malaria vectors have not been sufficient to determine its potential relative to current alternatives, much of which will hinge ultimately upon cost. These manuscripts provide an overview of current efforts to develop SIT and identify key research issues that remain.
Vector Potential Quantization and the Quantum Vacuum
Directory of Open Access Journals (Sweden)
Constantin Meis
2014-01-01
Full Text Available We investigate the quantization of the vector potential amplitude of the electromagnetic field to a single photon state starting from the fundamental link equations between the classical electromagnetic theory and the quantum mechanical expressions. The resulting wave-particle formalism ensures a coherent transition between the classical electromagnetic wave theory and the quantum representation. A quantization constant of the photon vector potential is defined. A new quantum vacuum description results directly in having very low energy density. The calculated spontaneous emission rate and Lambs shift for the nS states of the hydrogen atom are in agreement with quantum electrodynamics. This low energy quantum vacuum state might be compatible with recent astrophysical observations.
Approximate gauge symemtry of composite vector bosons
Energy Technology Data Exchange (ETDEWEB)
Suzuki, Mahiko
2010-06-01
It can be shown in a solvable field theory model that the couplings of the composite vector mesons made of a fermion pair approach the gauge couplings in the limit of strong binding. Although this phenomenon may appear accidental and special to the vector bosons made of a fermion pair, we extend it to the case of bosons being constituents and find that the same phenomenon occurs in more an intriguing way. The functional formalism not only facilitates computation but also provides us with a better insight into the generating mechanism of approximate gauge symmetry, in particular, how the strong binding and global current conservation conspire to generate such an approximate symmetry. Remarks are made on its possible relevance or irrelevance to electroweak and higher symmetries.
Lepton flavor violation with light vector bosons
Heeck, Julian
2016-01-01
New sub-GeV vector bosons with couplings to muons but not electrons have been discussed in order to explain the muon's magnetic moment, the gap of high-energy neutrinos in IceCube or the proton radius puzzle. If such a light Z' not only violates lepton universality but also lepton flavor, as expected for example from the recent hint for $h\\to\\mu\\tau$ at CMS, the two-body decay mode $\\tau \\to \\mu Z'$ opens up and for $M_{Z'} < 2 m_\\mu$ gives better constraints than $\\tau\\to 3\\mu$ already with 20-year-old ARGUS limits. We discuss the general prospects and motivation of light vector bosons with lepton-flavor-violating couplings.
The calibration of the vector polarimeter POLIS
Beck, C
2013-01-01
In this diploma thesis, the calibration of the vector polarimeter POLIS will be described. The instrument is built by the Kiepenheuer-Institut fuer Sonnenphysik (Freiburg/Germany) in cooperation with the High Altitude Observatory (Boulder/USA) and will be operated at the German Vacuum Tower Telescope in Tenerife. The instrument yields simultaneously the polarization state of light in two spectral ranges at 396 nm and 630 nm. The measurement is performed with a rotating retarder, which modulates the incident polarization. The modulation is transformed into a varying intensity through polarizing beamsplitters. The demodulation uses a weighted integration scheme to obtain the full Stokes vector of the radiation. The calibration of the polarimeter is performed through the evaluation of a calibration data set produced with a calibration unit consisting of a linear polarizer and a retarder. The instrumental calibration and the polarimetric model of the telescope are described in detail. This document is an unaltere...
Relativistic Thermodynamics: A Modern 4-Vector Approach
Directory of Open Access Journals (Sweden)
J. Güémez
2011-01-01
Full Text Available Using the Minkowski relativistic 4-vector formalism, based on Einstein's equation, and the relativistic thermodynamics asynchronous formulation (Grøn (1973, the isothermal compression of an ideal gas is analyzed, considering an electromagnetic origin for forces applied to it. This treatment is similar to the description previously developed by Van Kampen (van Kampen (1969 and Hamity (Hamity (1969. In this relativistic framework Mechanics and Thermodynamics merge in the first law of relativistic thermodynamics expressed, using 4-vector notation, such as ΔUμ = Wμ + Qμ, in Lorentz covariant formulation, which, with the covariant formalism for electromagnetic forces, constitutes a complete Lorentz covariant formulation for classical physics.
Quantum nonlinear lattices and coherent state vectors
DEFF Research Database (Denmark)
Ellinas, Demosthenes; Johansson, M.; Christiansen, Peter Leth
1999-01-01
(FP) model. Based on the respective dynamical symmetries of the models, a method is put forward which by use of the associated boson and spin coherent state vectors (CSV) and a factorization ansatz for the solution of the Schrodinger equation, leads to quasiclassical Hamiltonian equations of motion...... for the state vectors invokes the study of the Riemannian and symplectic geometry of the CSV manifolds as generalized phase spaces. Next, we investigate analytically and numerically the behavior of mean values and uncertainties of some physically interesting observables as well as the modifications...... in the quantum regime of processes such as the discrete self trapping (DST), in terms of the Q-function and the distribution of excitation quanta of the lattice sites. Quantum DST in the symmetric ordering of lattice operators is found to be relatively enhanced with respect to the classical DST. Finally...
Glueballs and vector mesons at NICA
Energy Technology Data Exchange (ETDEWEB)
Parganlija, Denis [Technische Universitaet Wien, Institut fuer Theoretische Physik, Vienna (Austria)
2016-08-15
Two interconnected fields of interest are suggested for NICA. Firstly, existence of glueballs is predicted by the theory of strong interaction but -even after decades of research- glueball identification in the physical spectrum is still unclear. NICA can help to ascertain experimental glueball candidates via J/Ψ decays whose yield is expected to be large. Importance of glueballs is not limited to vacuum: since they couple to other meson states, glueballs can also be expected to influence signatures of chiral-symmetry restoration in the high-energy phase of strong dynamics. Mass shifting or in-medium broadening of vector and axial-vector mesons may occur there but the extent of such phenomena is still uncertain. Additionally, glueball properties could also be modified in medium. Exploration of these issues is the second suggested field of interest that can be pursued at NICA. (orig.)
Experimental generation of amplitude squeezed vector beams
Chille, Vanessa; Semmler, Marion; Banzer, Peter; Aiello, Andrea; Leuchs, Gerd; Marquardt, Christoph
2016-01-01
We present an experimental method for the generation of amplitude squeezed high-order vector beams. The light is modified twice by a spatial light modulator such that the vector beam is created by means of a collinear interferometric technique. A major advantage of this approach is that it avoids systematic losses, which are detrimental as they cause decoherence in continuous-variable quantum systems. The utilisation of a spatial light modulator (SLM) gives the flexibility to switch between arbitrary mode orders. The conversion efficiency with our setup is only limited by the efficiency of the SLM. We show the experimental generation of Laguerre-Gauss (LG) modes with radial indices up to 1 and azimuthal indices up to 3 with complex polarization structures and a quantum noise reduction up to -0.9dB$\\pm$0.1dB. The corresponding polarization structures are studied in detail by measuring the spatial distribution of the Stokes parameters.
Higgsed Stueckelberg vector and Higgs quadratic divergence
Directory of Open Access Journals (Sweden)
Durmuş Ali Demir
2015-01-01
Full Text Available Here we show that, a hidden vector field whose gauge invariance is ensured by a Stueckelberg scalar and whose mass is spontaneously generated by the Standard Model Higgs field contributes to quadratic divergences in the Higgs boson mass squared, and even leads to its cancellation at one-loop when Higgs coupling to gauge field is fine-tuned. In contrast to mechanisms based on hidden scalars where a complete cancellation cannot be achieved, stabilization here is complete in that the hidden vector and the accompanying Stueckelberg scalar are both free from quadratic divergences at one-loop. This stability, deriving from hidden exact gauge invariance, can have important implications for modeling dark phenomena like dark matter, dark energy, dark photon and neutrino masses. The hidden fields can be produced at the LHC.
All-optical vector atomic magnetometer.
Patton, B; Zhivun, E; Hovde, D C; Budker, D
2014-07-04
We demonstrate an all-optical magnetometer capable of measuring the magnitude and direction of a magnetic field using nonlinear magneto-optical rotation in cesium vapor. Vector capability is added by effective modulation of the field along orthogonal axes and subsequent demodulation of the magnetic-resonance frequency. This modulation is provided by the ac Stark shift induced by circularly polarized laser beams. The sensor exhibits a demonstrated rms noise floor of ∼65 fT/√[Hz] in measurement of the field magnitude and 0.5 mrad/√[Hz] in the field direction; elimination of technical noise would improve these sensitivities to 12 fT/√[Hz] and 10 μrad/√[Hz], respectively. Applications for this all-optical vector magnetometer would include magnetically sensitive fundamental physics experiments, such as the search for a permanent electric dipole moment of the neutron.
Vector mesons in strongly interacting matter
Indian Academy of Sciences (India)
Volker Metag
2010-08-01
Properties of hadrons in strongly interacting matter provide a link between quantum chromodynamics in the strong coupling regime and experimental observables. QCD sum rules show that changes in chiral and higher-order condensates, partially associated with a restoration of chiral symmetry in the nuclear medium, will lead to significant changes in the low-energy spectrum of hadrons. Heavy-ion collisions and reactions with elementary probes have been used to extract experimental information on in-medium properties of hadrons. Results on the light vector mesons ρ, , and , are summarized and compared. Almost all experiments report a softening of the spectral functions with increases in width depending on the density and temperature of the hadronic environment. No evidence for mass shifts is found in majority of the experiments. Remaining inconsistencies among experimental results demonstrate the need for further measurements with higher statistics and inrceased acceptance in particular for low-momentum vector mesons.
Online support vector regression for reinforcement learning
Institute of Scientific and Technical Information of China (English)
Yu Zhenhua; Cai Yuanli
2007-01-01
The goal in reinforcement learning is to learn the value of state-action pair in order to maximize the total reward. For continuous states and actions in the real world, the representation of value functions is critical. Furthermore, the samples in value functions are sequentially obtained. Therefore, an online support vector regression (OSVR) is set up, which is a function approximator to estimate value functions in reinforcement learning. OSVR updates the regression function by analyzing the possible variation of support vector sets after new samples are inserted to the training set. To evaluate the OSVR learning ability, it is applied to the mountain-car task. The simulation results indicate that the OSVR has a preferable convergence speed and can solve continuous problems that are infeasible using lookup table.
Elements of mathematics topological vector spaces
Bourbaki, Nicolas
2003-01-01
This is a softcover reprint of the English translation of 1987 of the second edition of Bourbaki's Espaces Vectoriels Topologiques (1981). This second edition is a brand new book and completely supersedes the original version of nearly 30 years ago. But a lot of the material has been rearranged, rewritten, or replaced by a more up-to-date exposition, and a good deal of new material has been incorporated in this book, all reflecting the progress made in the field during the last three decades. Table of Contents. Chapter I: Topological vector spaces over a valued field. Chapter II: Convex sets and locally convex spaces. Chapter III: Spaces of continuous linear mappings. Chapter IV: Duality in topological vector spaces. Chapter V: Hilbert spaces (elementary theory). Finally, there are the usual "historical note", bibliography, index of notation, index of terminology, and a list of some important properties of Banach spaces. (Based on Math Reviews, 1983).
Light Vector Mesons in the Nuclear Medium
Energy Technology Data Exchange (ETDEWEB)
Wood, Michael; Nasseripour, Rakhsha; Weygand, Dennis; Djalali, Chaden; Tur, Clarisse; Mosel, Ulrich; Muehlich, Pascal; Adams, Gary; Amaryan, Moscov; Amaryan, Moskov; Ambrozewicz, Pawel; Anghinolfi, Marco; Asryan, Gegham; Avagyan, Harutyun; Baghdasaryan, Hovhannes; Baillie, Nathan; Ball, James; Baltzell, Nathan; Barrow, Steve; Battaglieri, Marco; Bedlinskiy, Ivan; Bektasoglu, Mehmet; Bellis, Matthew; Benmouna, Nawal; Berman, Barry; Biselli, Angela; Blaszczyk, Lukasz; Bouchigny, Sylvain; Boyarinov, Sergey; Bradford, Robert; Branford, Derek; Briscoe, William; Brooks, William; Burkert, Volker; Butuceanu, Cornel; Calarco, John; Careccia, Sharon; Carman, Daniel; Carnahan, Bryan; Casey, Liam; Chen, Shifeng; Cheng, Lu; Cole, Philip; Collins, Patrick; Coltharp, Philip; Crabb, Donald; Crannell, Hall; Crede, Volker; Cummings, John; Dashyan, Natalya; De Vita, Raffaella; De Sanctis, Enzo; Degtiarenko, Pavel; Denizli, Haluk; Dennis, Lawrence; Deur, Alexandre; Dharmawardane, Kahanawita; Dickson, Richard; Dodge, Gail; Doughty, David; Dugger, Michael; Dytman, Steven; Dzyubak, Oleksandr; Egiyan, Hovanes; Egiyan, Kim; Elfassi, Lamiaa; Elouadrhiri, Latifa; Eugenio, Paul; Fedotov, Gleb; Feldman, Gerald; Feuerbach, Robert; Fradi, Ahmed; Funsten, Herbert; Garcon, Michel; Gavalian, Gagik; Gilfoyle, Gerard; Giovanetti, Kevin; Girod, Francois-Xavier; Goetz, John; Gordon, Christopher; Gothe, Ralf; Griffioen, Keith; Guidal, Michel; Guler, Nevzat; Guo, Lei; Gyurjyan, Vardan; Hadjidakis, Cynthia; Hafidi, Kawtar; Hakobyan, Hayk; Hakobyan, Rafael; Hanretty, Charles; Hardie, John; Hassall, Neil; Hersman, F.; Hicks, Kenneth; Hleiqawi, Ishaq; Holtrop, Maurik; Hyde, Charles; Ilieva, Yordanka; Ireland, David; Ishkhanov, Boris; Isupov, Evgeny; Ito, Mark; Jenkins, David; Jo, Hyon-Suk; Johnstone, John; Joo, Kyungseon; Juengst, Henry; Kalantarians, Narbe; Kellie, James; Khandaker, Mahbubul; Khetarpal, Puneet; Kim, Wooyoung; Klein, Andreas; Klein, Franz; Klimenko, Alexei; Kossov, Mikhail; Krahn, Zebulun; Kramer, Laird; Kubarovsky, Valery; Kuhn, Joachim; Kuhn, Sebastian; Kuleshov, Sergey; Lachniet, Jeff; Laget, Jean; Langheinrich, Jorn; Lawrence, David; Li, Ji; Livingston, Kenneth; Lu, Haiyun; MacCormick, Marion; Markov, Nikolai; Mattione, Paul; McAleer, Simeon; McKinnon, Bryan; McNabb, John; Mecking, Bernhard; Mehrabyan, Surik; Melone, Joseph; Mestayer, Mac; Meyer, Curtis; Mibe, Tsutomu; Mikhaylov, Konstantin; Minehart, Ralph; Mirazita, Marco; Miskimen, Rory; Mokeev, Viktor; Moriya, Kei; Morrow, Steven; Moteabbed, Maryam; Mueller, James; Munevar Espitia, Edwin; Mutchler, Gordon; Nadel-Turonski, Pawel; Niccolai, Silvia; Niculescu, Gabriel; Niculescu, Maria-Ioana; Niczyporuk, Bogdan; Niroula, Megh; Niyazov, Rustam; Nozar, Mina; Osipenko, Mikhail; Ostrovidov, Alexander; Park, Kijun; Pasyuk, Evgueni; Paterson, Craig; Pereira, Sergio; Pierce, Joshua; Pivnyuk, Nikolay; Pocanic, Dinko; Pogorelko, Oleg; Pozdnyakov, Sergey; Preedom, Barry; Price, John; Prok, Yelena; Protopopescu, Dan; Raue, Brian; Riccardi, Gregory; Ricco, Giovanni; Ripani, Marco; Ritchie, Barry; Ronchetti, Federico; Rosner, Guenther; Rossi, Patrizia; Sabatie, Franck; Salamanca, Julian; Salgado, Carlos; Santoro, Joseph; Sapunenko, Vladimir; Schumacher, Reinhard; Serov, Vladimir; Sharabian, Youri; Sharov, Dmitri; Shvedunov, Nikolay; Smith, Elton; Smith, Lee; Sober, Daniel; Sokhan, Daria; Stavinsky, Aleksey; Stepanyan, Stepan; Stepanyan, Samuel; Stokes, Burnham; Stoler, Paul; Strakovski, Igor; Strauch, Steffen; Taiuti, Mauro; Tedeschi, David; Tkabladze, Avtandil; Tkachenko, Svyatoslav; Todor, Luminita; Ungaro, Maurizio; Vineyard, Michael; Vlassov, Alexander; Watts, Daniel; Weinstein, Lawrence; Williams, Michael; Wolin, Elliott; Yegneswaran, Amrit; Zana, Lorenzo; Zhang, Bin; Zhang, Jixie; Zhao, Bo; Zhao, Zhiwen
2008-07-01
The light vector mesons ($\\rho$, $\\omega$, and $\\phi$) were produced in deuterium, carbon, titanium, and iron targets in a search for possible in-medium modifications to the properties of the $\\rho$ meson at normal nuclear densities and zero temperature. The vector mesons were detected with the CEBAF Large Acceptance Spectrometer (CLAS) via their decays to $e^{+}e^{-}$. The rare leptonic decay was chosen to reduce final-state interactions. A combinatorial background was subtracted from the invariant mass spectra using a well-established event-mixing technique. The $\\rho$ meson mass spectrum was extracted after the $\\omega$ and $\\phi$ signals were removed in a nearly model-independent way. Comparisons were made between the $\\rho$ mass spectra from the heavy targets ($A > 2$) with the mass spectrum extracted from the deuterium target. With respect to the $\\rho$-meson mass, we obtain a small shift compatible with zero. Also, we measure widths consistent with standard nuclear many-body eff
Improving the lattice axial vector current
Horsley, R; Perlt, H; Rakow, P E L; Schierholz, G; Schiller, A; Zanotti, J M
2015-01-01
For Wilson and clover fermions traditional formulations of the axial vector current do not respect the continuum Ward identity which relates the divergence of that current to the pseudoscalar density. Here we propose to use a point-split or one-link axial vector current whose divergence exactly satisfies a lattice Ward identity, involving the pseudoscalar density and a number of irrelevant operators. We check in one-loop lattice perturbation theory with SLiNC fermion and gauge plaquette action that this is indeed the case including order $O(a)$ effects. Including these operators the axial Ward identity remains renormalisation invariant. First preliminary results of a nonperturbative check of the Ward identity are also presented.
Shuttle vectors for the archaebacterium Halobacterium volcanii.
Lam, W. L.; Doolittle, W F
1989-01-01
Progress in archaebacterial molecular biology requires tools for genetic analysis. We describe vectors that can be selected and maintained in either Halobacterium volcanii or Escherichia coli. A genetic determinant for resistance to the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor mevinolin was isolated by "shotgun cloning" into a derivative of the endogenous H. volcanii plasmid pHV2, to form pWL2, which transforms sensitive H. volcanii to mevinolin resistance at high frequency. ...
Image Segmentation Based on Support Vector Machine
Institute of Scientific and Technical Information of China (English)
XU Hai-xiang; ZHU Guang-xi; TIAN Jin-wen; ZHANG Xiang; PENG Fu-yuan
2005-01-01
Image segmentation is a necessary step in image analysis. Support vector machine (SVM) approach is proposed to segment images and its segmentation performance is evaluated.Experimental results show that: the effects of kernel function and model parameters on the segmentation performance are significant; SVM approach is less sensitive to noise in image segmentation; The segmentation performance of SVM approach is better than that of back-propagation multi-layer perceptron (BP-MLP) approach and fuzzy c-means (FCM) approach.
A vector space approach to geometry
Hausner, Melvin
2010-01-01
The effects of geometry and linear algebra on each other receive close attention in this examination of geometry's correlation with other branches of math and science. In-depth discussions include a review of systematic geometric motivations in vector space theory and matrix theory; the use of the center of mass in geometry, with an introduction to barycentric coordinates; axiomatic development of determinants in a chapter dealing with area and volume; and a careful consideration of the particle problem. 1965 edition.
The evolution of heart gene delivery vectors
Wasala, Nalinda B.; Shin, Jin-Hong; Duan, Dongsheng
2011-01-01
Gene therapy holds promise for treating numerous heart diseases. A key premise for the success of cardiac gene therapy is the development of powerful gene transfer vehicles that can achieve highly efficient and persistent gene transfer specifically in the heart. Other features of an ideal vector include negligible toxicity, minimal immunogenicity and easy manufacturing. Rapid progress in the fields of molecular biology and virology has offered great opportunities to engineer various genetic m...
Matching the Heavy Vector Meson Theory
Bijnens, J; Talavera, P
1998-01-01
We show how to obtain a ``heavy'' meson effective lagrangian for the case where the number of heavy particles is not conserved. We apply the method in a simple example at tree level and perform then the reduction for the case of vector mesons in Chiral Perturbation Theory in a manifestly chiral invariant fashion. Some examples showing that ``heavy'' meson effective theory also works at the one-loop level are included.
Computerized Interactive Gaming via Supporting Vector Machines
Jiang, Yang; Jiang, Jianmin; Palmer, Ian
2008-01-01
Computerized interactive gaming requires automatic processing of large volume of random data produced by players on spot, such as shooting, football kicking, and boxing. This paper describes a supporting vector machine-based artificial intelligence algorithm as one of the possible solutions to the problem of random data processing and the provision of interactive indication for further actions. In comparison with existing techniques, such as rule-based and neural networks, and so forth, our S...
The quantum vector digital voltmeter of INMETRO
Kuerten Ihlenfeld, Waldemar G.; Landim, Regis P.
2016-07-01
The paper describes the quantum vector digital voltmeter developed at INMETRO, which is based on a programmable Josephson voltage synthesizer. The system employs digital regulation for phase-alignment and frequency synchronization of signals, is fully automated and allows calibration of ac sources and analog-to-digital converters with uncertainties bearing some parts of 10-07 up to frequencies of around 500 Hz.
Characterizing Compromise Stability of Games Using Larginal Vectors
Platz, T.T.; Hamers, H.J.M.; Quant, M.
2011-01-01
The core cover of a TU-game is a superset of the core and equals the convex hull of its larginal vectors. A larginal vector corresponds to an order of the players and describes the efficient payoff vector giving the first players in the order their utopia demand as long as it is still possible to as
Scaffolding Vector Representations for Student Learning inside a Physics Game
D'Angelo Cynthia
2010-01-01
Vectors and vector addition are difficult concepts for many introductory physics students and traditional instruction does not usually sufficiently address these difficulties. Vectors play a major role in most topics in introductory physics and without a complete understanding of them many students are unable to make sense of the physics topics…
Examples of in-vivo blood vector velocity estimation
DEFF Research Database (Denmark)
Udesen, Jesper; Nielsen, Michael Bachmann; Nielsen, Kristian R.
2007-01-01
In this paper examples of in-vivo blood vector velocity images of the carotid artery are presented. The transverse oscillation (TO) method for blood vector velocity estimation has been used to estimate the vector velocities and the method is first evaluated in a circulating flowrig where...
The $\\gamma$-vector of a barycentric subdivision
Nevo, Eran; Tenner, Bridget Eileen
2010-01-01
We prove that the $\\gamma$-vector of the barycentric subdivision of a simplicial sphere is the $f$-vector of a balanced simplicial complex. The combinatorial basis for this work is the study of certain refinements of Eulerian numbers used by Brenti and Welker to describe the $h$-vector of the barycentric subdivision of a boolean complex.
Arterial secondary blood flow patterns visualized with vector flow ultrasound
DEFF Research Database (Denmark)
Pedersen, Mads Møller; Pihl, Michael Johannes; Hansen, Jens Munk
2011-01-01
This study presents the first quantification and visualisation of secondary flow patterns with vector flow ultrasound. The first commercial implementation of the vector flow method Transverse Oscillation was used to obtain in-vivo, 2D vector fields in real-time. The hypothesis of this study...
Intragenic vectors for gene transfer without foreign DNA
Conner, A.J.; Barrell, P.J.; Baldwin, S.J.; Lokerse, A.S.; Cooper, P.A.; Erasmuson, A.K.; Nap, J.P.H.; Jacobs, J.M.E.
2007-01-01
The intragenic vector system involves identifying functional equivalents of vector components from the genome of a specific crop species (or related species to which it can be hybridised) and using these DNA sequences to assemble vectors for transformation of that plant species. This system offers a
Hyperorthogonal family of vectors and the associated Gram matrix
DEFF Research Database (Denmark)
Fuglede, Bent
2014-01-01
A family of non-zero vectors in Euclidean n -space is termed hyperorthogonal if the angle between any two distinct vectors of the family is at least π/2 . Any hyperorthogonal family is finite and contains at most 2n vectors. It decomposes uniquely into the union of mutually orthogonal irreducible...
40 CFR 258.22 - Disease vector control.
2010-07-01
... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Disease vector control. 258.22 Section... MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.22 Disease vector control. (a) Owners or operators of all MSWLF units must prevent or control on-site populations of disease vectors using...
42 CFR 71.54 - Etiological agents, hosts, and vectors.
2010-10-01
... 42 Public Health 1 2010-10-01 2010-10-01 false Etiological agents, hosts, and vectors. 71.54..., INSPECTION, LICENSING FOREIGN QUARANTINE Importations § 71.54 Etiological agents, hosts, and vectors. (a) A... any arthropod or other animal host or vector of human disease, or any exotic living arthropod or...
Environmental statistical modelling of mosquito vectors at different geographical scales
Cianci, D.
2015-01-01
Vector-borne diseases are infections transmitted by the bite of infected arthropod vectors, such as mosquitoes, ticks, fleas, midges and flies. Vector-borne diseases pose an increasingly wider threat to global public health, both in terms of people affected and their geographical spread. Mosquitoes
Declining Prevalence of Disease Vectors Under Climate Change
Escobar, Luis E.; Romero-Alvarez, Daniel; Leon, Renato; Lepe-Lopez, Manuel A.; Craft, Meggan E.; Borbor-Cordova, Mercy J.; Svenning, Jens-Christian
2016-12-01
More than half of the world population is at risk of vector-borne diseases including dengue fever, chikungunya, zika, yellow fever, leishmaniasis, chagas disease, and malaria, with highest incidences in tropical regions. In Ecuador, vector-borne diseases are present from coastal and Amazonian regions to the Andes Mountains; however, a detailed characterization of the distribution of their vectors has never been carried out. We estimate the distribution of 14 vectors of the above vector-borne diseases under present-day and future climates. Our results consistently suggest that climate warming is likely threatening some vector species with extinction, locally or completely. These results suggest that climate change could reduce the burden of specific vector species. Other vector species are likely to shift and constrain their geographic range to the highlands in Ecuador potentially affecting novel areas and populations. These forecasts show the need for development of early prevention strategies for vector species currently absent in areas projected as suitable under future climate conditions. Informed interventions could reduce the risk of human exposure to vector species with distributional shifts, in response to current and future climate changes. Based on the mixed effects of future climate on human exposure to disease vectors, we argue that research on vector-borne diseases should be cross-scale and include climatic, demographic, and landscape factors, as well as forces facilitating disease transmission at fine scales.
Large Animal Models for Foamy Virus Vector Gene Therapy
Directory of Open Access Journals (Sweden)
Peter A. Horn
2012-12-01
Full Text Available Foamy virus (FV vectors have shown great promise for hematopoietic stem cell (HSC gene therapy. Their ability to efficiently deliver transgenes to multi-lineage long-term repopulating cells in large animal models suggests they will be effective for several human hematopoietic diseases. Here, we review FV vector studies in large animal models, including the use of FV vectors with the mutant O6-methylguanine-DNA methyltransferase, MGMTP140K to increase the number of genetically modified cells after transplantation. In these studies, FV vectors have mediated efficient gene transfer to polyclonal repopulating cells using short ex vivo transduction protocols designed to minimize the negative effects of ex vivo culture on stem cell engraftment. In this regard, FV vectors appear superior to gammaretroviral vectors, which require longer ex vivo culture to effect efficient transduction. FV vectors have also compared favorably with lentiviral vectors when directly compared in the dog model. FV vectors have corrected leukocyte adhesion deficiency and pyruvate kinase deficiency in the dog large animal model. FV vectors also appear safer than gammaretroviral vectors based on a reduced frequency of integrants near promoters and also near proto-oncogenes in canine repopulating cells. Together, these studies suggest that FV vectors should be highly effective for several human hematopoietic diseases, including those that will require relatively high percentages of gene-modified cells to achieve clinical benefit.
Anisotropic cosmological solutions in massive vector theories
Heisenberg, Lavinia; Tsujikawa, Shinji
2016-01-01
In beyond-generalized Proca theories including the extension to theories higher than second order, we study the role of a spatial component $v$ of a massive vector field on the anisotropic cosmological background. We show that, as in the case of the isotropic cosmological background, there is no additional ghostly degrees of freedom associated with the Ostrogradski instability. In second-order generalized Proca theories we find the existence of anisotropic solutions on which the ratio between the anisotropic expansion rate $\\Sigma$ and the isotropic expansion rate $H$ remains nearly constant in the radiation-dominated epoch. In the regime where $\\Sigma/H$ is constant, the spatial vector component $v$ works as a dark radiation with the equation of state close to $1/3$. During the matter era, the ratio $\\Sigma/H$ decreases with the decrease of $v$. As long as the conditions $|\\Sigma| \\ll H$ and $v^2 \\ll \\phi^2$ are satisfied around the onset of late-time cosmic acceleration, where $\\phi$ is the temporal vector ...
Multifractal vector fields and stochastic Clifford algebra
Energy Technology Data Exchange (ETDEWEB)
Schertzer, Daniel, E-mail: Daniel.Schertzer@enpc.fr; Tchiguirinskaia, Ioulia, E-mail: Ioulia.Tchiguirinskaia@enpc.fr [University Paris-Est, Ecole des Ponts ParisTech, Hydrology Meteorology and Complexity HM& Co, Marne-la-Vallée (France)
2015-12-15
In the mid 1980s, the development of multifractal concepts and techniques was an important breakthrough for complex system analysis and simulation, in particular, in turbulence and hydrology. Multifractals indeed aimed to track and simulate the scaling singularities of the underlying equations instead of relying on numerical, scale truncated simulations or on simplified conceptual models. However, this development has been rather limited to deal with scalar fields, whereas most of the fields of interest are vector-valued or even manifold-valued. We show in this paper that the combination of stable Lévy processes with Clifford algebra is a good candidate to bridge up the present gap between theory and applications. We show that it indeed defines a convenient framework to generate multifractal vector fields, possibly multifractal manifold-valued fields, based on a few fundamental and complementary properties of Lévy processes and Clifford algebra. In particular, the vector structure of these algebra is much more tractable than the manifold structure of symmetry groups while the Lévy stability grants a given statistical universality.
ATLAS measurements of vector boson production
Debenedetti, Chiara; The ATLAS collaboration
2016-01-01
Vector boson production in pp collisions at 7, 8 and 13 TeV has been extensively studied by ATLAS. Recent results include the precision measurements of the transverse momentum of the Z/gamma* boson production, sensitive to soft resummation effects, hard jet emissions and electroweak corrections. A precise measurement of the angular coefficients of the Zboson production tests the underlying QCD dynamics of the DrellYan process. A first measurement of the inclusive W and Z cross section at a cms energy of 13TeV has been derived. The Production of jets in association with a vector boson is an important process to study QCD in a multiscale environment. Cross sections, differential in several kinematics variables, have been measured with the ATLAS detector and compared to stateoftheart QCD calculations and Monte Carlo simulations. First measurements of vector boson + jets production have been performed at cms energies of 13TeV. An overview of these results is given.
Pattern vectors from algebraic graph theory.
Wilson, Richard C; Hancock, Edwin R; Luo, Bin
2005-07-01
Graph structures have proven computationally cumbersome for pattern analysis. The reason for this is that, before graphs can be converted to pattern vectors, correspondences must be established between the nodes of structures which are potentially of different size. To overcome this problem, in this paper, we turn to the spectral decomposition of the Laplacian matrix. We show how the elements of the spectral matrix for the Laplacian can be used to construct symmetric polynomials that are permutation invariants. The coefficients of these polynomials can be used as graph features which can be encoded in a vectorial manner. We extend this representation to graphs in which there are unary attributes on the nodes and binary attributes on the edges by using the spectral decomposition of a Hermitian property matrix that can be viewed as a complex analogue of the Laplacian. To embed the graphs in a pattern space, we explore whether the vectors of invariants can be embedded in a low-dimensional space using a number of alternative strategies, including principal components analysis (PCA), multidimensional scaling (MDS), and locality preserving projection (LPP). Experimentally, we demonstrate that the embeddings result in well-defined graph clusters. Our experiments with the spectral representation involve both synthetic and real-world data. The experiments with synthetic data demonstrate that the distances between spectral feature vectors can be used to discriminate between graphs on the basis of their structure. The real-world experiments show that the method can be used to locate clusters of graphs.
Live bacterial vaccine vectors: An overview
Directory of Open Access Journals (Sweden)
Adilson José da Silva
2014-12-01
Full Text Available Genetically attenuated microorganisms, pathogens, and some commensal bacteria can be engineered to deliver recombinant heterologous antigens to stimulate the host immune system, while still offering good levels of safety. A key feature of these live vectors is their capacity to stimulate mucosal as well as humoral and/or cellular systemic immunity. This enables the use of different forms of vaccination to prevent pathogen colonization of mucosal tissues, the front door for many infectious agents. Furthermore, delivery of DNA vaccines and immune system stimulatory molecules, such as cytokines, can be achieved using these special carriers, whose adjuvant properties and, sometimes, invasive capacities enhance the immune response. More recently, the unique features and versatility of these vectors have also been exploited to develop anti-cancer vaccines, where tumor-associated antigens, cytokines, and DNA or RNA molecules are delivered. Different strategies and genetic tools are constantly being developed, increasing the antigenic potential of agents delivered by these systems, opening fresh perspectives for the deployment of vehicles for new purposes. Here we summarize the main characteristics of the different types of live bacterial vectors and discuss new applications of these delivery systems in the field of vaccinology.
Multifractal vector fields and stochastic Clifford algebra.
Schertzer, Daniel; Tchiguirinskaia, Ioulia
2015-12-01
In the mid 1980s, the development of multifractal concepts and techniques was an important breakthrough for complex system analysis and simulation, in particular, in turbulence and hydrology. Multifractals indeed aimed to track and simulate the scaling singularities of the underlying equations instead of relying on numerical, scale truncated simulations or on simplified conceptual models. However, this development has been rather limited to deal with scalar fields, whereas most of the fields of interest are vector-valued or even manifold-valued. We show in this paper that the combination of stable Lévy processes with Clifford algebra is a good candidate to bridge up the present gap between theory and applications. We show that it indeed defines a convenient framework to generate multifractal vector fields, possibly multifractal manifold-valued fields, based on a few fundamental and complementary properties of Lévy processes and Clifford algebra. In particular, the vector structure of these algebra is much more tractable than the manifold structure of symmetry groups while the Lévy stability grants a given statistical universality.
Test of understanding of vectors: A reliable multiple-choice vector concept test
Barniol, Pablo; Zavala, Genaro
2014-06-01
In this article we discuss the findings of our research on students' understanding of vector concepts in problems without physical context. First, we develop a complete taxonomy of the most frequent errors made by university students when learning vector concepts. This study is based on the results of several test administrations of open-ended problems in which a total of 2067 students participated. Using this taxonomy, we then designed a 20-item multiple-choice test [Test of understanding of vectors (TUV)] and administered it in English to 423 students who were completing the required sequence of introductory physics courses at a large private Mexican university. We evaluated the test's content validity, reliability, and discriminatory power. The results indicate that the TUV is a reliable assessment tool. We also conducted a detailed analysis of the students' understanding of the vector concepts evaluated in the test. The TUV is included in the Supplemental Material as a resource for other researchers studying vector learning, as well as instructors teaching the material.
Energy Technology Data Exchange (ETDEWEB)
Husek, Tomas [Charles University, Faculty of Mathematics and Physics, Institute of Particle and Nuclear Physics, Prague 8 (Czech Republic); Leupold, Stefan [Uppsala Universitet, Institutionen foer Fysik och Astronomi, Box 516, Uppsala (Sweden)
2015-12-15
The pseudoscalar-vector-vector correlator is constructed using two meson multiplets in the vector and two in the pseudoscalar channel. The parameters are constrained by the operator product expansion at leading order where two or all three momenta are considered as large. Demanding in addition the Brodsky-Lepage limit one obtains (in the chiral limit) pion-vector-vector (πVV) correlator with only one free parameter. The singly virtual pion transition form factor F{sub π{sup 0}γγ*} and the decay width of ω → π{sup 0}γ are independent of this parameter and can serve as cross-checks of the results. The free parameter is determined from a fit of the ω-π transition form factor F{sub π{sup 0}ωγ*}. The resulting πVV correlator is used to calculate the decay widths ω → π{sup 0}e{sup +}e{sup -} and ω → π{sup 0}μ{sup +}μ{sup -} and finally the widths of the rare decay π{sup 0} → e{sup +}e{sup -} and of the Dalitz decay π{sup 0} → e{sup +}e{sup -}γ. Incorporating radiative QED corrections the calculations of π{sup 0} decays are compared to the KTeV results. We find a deviation of 2 σ or less for the rare pion decay. (orig.)
Thresholds and Smooth Transitions in Vector Autoregressive Models
DEFF Research Database (Denmark)
Hubrich, Kirstin; Teräsvirta, Timo
This survey focuses on two families of nonlinear vector time series models, the family of Vector Threshold Regression models and that of Vector Smooth Transition Regression models. These two model classes contain incomplete models in the sense that strongly exogeneous variables are allowed...... in the equations. The emphasis is on stationary models, but the considerations also include nonstationary Vector Threshold Regression and Vector Smooth Transition Regression models with cointegrated variables. Model specification, estimation and evaluation is considered, and the use of the models illustrated...
A Note on Polarization Vectors in Quantum Electrodynamics
Lieb, Elliott H.; Loss, Michael
2004-12-01
A photon of momentum k can have only two polarization states, not three. Equivalently, one can say that the magnetic vector potential A must be divergence-free in the Coulomb gauge. These facts are normally taken into account in QED by introducing two polarization vectors ɛλ(k) with λ ∈ {1,2}, which are orthogonal to the wave-vector k. These vectors must be very discontinuous functions of k and, consequently, their Fourier transforms have bad decay properties. Since these vectors have no physical significance there must be a way to eliminate them and their bad decay properties from the theory. We propose such a way here.
The Helmholtz decomposition of decreasing and weakly increasing vector fields
Petrascheck, D
2015-01-01
Helmholtz decomposition theorem for vector fields is presented usually with too strong restrictions on the fields. Based on the work of Blumenthal of 1905 it is shown that the decomposition of vector fields is not only possible for asymptotically weakly decreasing vector fields, but even for vector fields, which asymptotically increase sublinearly. Use is made of a regularizatin of the Greens function and the mathematics of the proof is formulated as simply as possible. We also show a few examples for the decomposition of vector fields including the electric dipole radiation.
Cohen-Macaulay graphs and face vectors of flag complexes
Cook, David
2010-01-01
We introduce three constructions for a graph $G$ that associate to the independence complex of $G$ a flag complex whose $h$-vector is the $f$-vector of the original complex. Two of these constructions produce vertex-decomposable, hence Cohen-Macaulay, complexes. It follows that the $f$-vector of a flag complex is the $h$-vector of a vertex-decomposable flag complex. We conjecture that the converse is true and prove this for $h$-vectors of Cohen-Macaulay independence complexes of bipartite graphs. We also give several new characterisations of bipartite graphs with Cohen-Macaulay or Buchsbaum independence complexes.
Advances in Non-Viral DNA Vectors for Gene Therapy
Hardee, Cinnamon L.; Arévalo-Soliz, Lirio Milenka; Hornstein, Benjamin D.; Zechiedrich, Lynn
2017-01-01
Uses of viral vectors have thus far eclipsed uses of non-viral vectors for gene therapy delivery in the clinic. Viral vectors, however, have certain issues involving genome integration, the inability to be delivered repeatedly, and possible host rejection. Fortunately, development of non-viral DNA vectors has progressed steadily, especially in plasmid vector length reduction, now allowing these tools to fill in specifically where viral or other non-viral vectors may not be the best options. In this review, we examine the improvements made to non-viral DNA gene therapy vectors, highlight opportunities for their further development, address therapeutic needs for which their use is the logical choice, and discuss their future expansion into the clinic. PMID:28208635
Effective SIMD Vectorization for Intel Xeon Phi Coprocessors
Directory of Open Access Journals (Sweden)
Xinmin Tian
2015-01-01
Full Text Available Efficiently exploiting SIMD vector units is one of the most important aspects in achieving high performance of the application code running on Intel Xeon Phi coprocessors. In this paper, we present several effective SIMD vectorization techniques such as less-than-full-vector loop vectorization, Intel MIC specific alignment optimization, and small matrix transpose/multiplication 2D vectorization implemented in the Intel C/C++ and Fortran production compilers for Intel Xeon Phi coprocessors. A set of workloads from several application domains is employed to conduct the performance study of our SIMD vectorization techniques. The performance results show that we achieved up to 12.5x performance gain on the Intel Xeon Phi coprocessor. We also demonstrate a 2000x performance speedup from the seamless integration of SIMD vectorization and parallelization.
Advances in Non-Viral DNA Vectors for Gene Therapy
Directory of Open Access Journals (Sweden)
Cinnamon L. Hardee
2017-02-01
Full Text Available Uses of viral vectors have thus far eclipsed uses of non-viral vectors for gene therapy delivery in the clinic. Viral vectors, however, have certain issues involving genome integration, the inability to be delivered repeatedly, and possible host rejection. Fortunately, development of non-viral DNA vectors has progressed steadily, especially in plasmid vector length reduction, now allowing these tools to fill in specifically where viral or other non-viral vectors may not be the best options. In this review, we examine the improvements made to non-viral DNA gene therapy vectors, highlight opportunities for their further development, address therapeutic needs for which their use is the logical choice, and discuss their future expansion into the clinic
Lyapunov, Floquet, and singular vectors for baroclinic waves
Directory of Open Access Journals (Sweden)
R. M. Samelson
2001-01-01
Full Text Available The dynamics of the growth of linear disturbances to a chaotic basic state is analyzed in an asymptotic model of weakly nonlinear, baroclinic wave-mean interaction. In this model, an ordinary differential equation for the wave amplitude is coupled to a partial differential equation for the zonal flow correction. The leading Lyapunov vector is nearly parallel to the leading Floquet vector f1 of the lowest-order unstable periodic orbit over most of the attractor. Departures of the Lyapunov vector from this orientation are primarily rotations of the vector in an approximate tangent plane to the large-scale attractor structure. Exponential growth and decay rates of the Lyapunov vector during individual Poincaré section returns are an order of magnitude larger than the Lyapunov exponent l ≈ 0.016. Relatively large deviations of the Lyapunov vector from parallel to f1 are generally associated with relatively large transient decays. The transient growth and decay of the Lyapunov vector is well described by the transient growth and decay of the leading Floquet vectors of the set of unstable periodic orbits associated with the attractor. Each of these vectors is also nearly parallel to f1. The dynamical splitting of the complete sets of Floquet vectors for the higher-order cycles follows the previous results on the lowest-order cycle, with the vectors divided into wave-dynamical and decaying zonal flow modes. Singular vectors and singular values also generally follow this split. The primary difference between the leading Lyapunov and singular vectors is the contribution of decaying, inviscidly-damped wave-dynamical structures to the singular vectors.
Forecasting Coronal Mass Ejections from Vector Magnetograms
Falconer, D. A.; Moore, R. L.; Gary, G. A.; Six, N. Frank (Technical Monitor)
2002-01-01
In a 17 vector magnetogram study of 12 bipolar active regions (Falconer, Moore, & Gary, 2002, ApJ in press), we correlated four quantitative global magnetic measures with the Coronal Mass Ejections (CME) productivity of the active region. The global measures included a measure of active region size, the total magnetic flux phi and three measures of an active region global nonpotentiality 1) the net current (I (sub N)), 2) the length of the strong-shear, strong-field main neutral line (L(sub SS)) and 3) and the normalized twist (alpha = muIN/PHI). The CME productivity was determined from YOHKOH/SXT observations, Geostationary Operational Environmental Satellite (GOES), and when possible Solar and Heliospheric Observatory/Large Angle and Spectrometric Coronagraph Experiment (SOHO/LASCO) observations within 12 days of the day of the magnetogram. We found that the three measures of global nonpotentiality (I(sub N), L(sub SS), alpha) were all well correlated (greater than 99% confidence level) with an active region's CME productivity. The sample size was to small to confirm if there was a statistical significant correlation of the globally nonscientist measures with future CME activity (i.e. from the date of the magnetogram forward). We are doubling our sample, and will report on the statistical significance of global nonpotentiality as a predictor of future CME productivity. The new active regions are all from the first year of the upgraded MSFC vector magnetograms. This work, is funded by NSF through the Space Weather Program, by NASA through the Living with the Star, Targeted Research and Technology, and by NASA Solar Physics Supporting Research and Technology Program. The upgrade to the MSFC vector magnetograph was supported by the High Energy Solar Spectroscopic Imager (HESSI) mission.
Holographic picture of heavy vector meson melting
Energy Technology Data Exchange (ETDEWEB)
Braga, Nelson R.F.; Diles, Saulo [Universidade Federal do Rio de Janeiro, Instituto de Fisica, Rio de Janeiro, RJ (Brazil); Martin Contreras, Miguel Angel [Universidad de los Andes, High Energy Group, Department of Physics, Bogota (Colombia)
2016-11-15
The fraction of heavy vector mesons produced in a heavy ion collision, as compared to a proton-proton collision, serves as an important indication of the formation of a thermal medium, the quark-gluon plasma. This sort of analysis strongly depends on understanding the thermal effects of a medium like the plasma on the states of heavy mesons. In particular, it is crucial to know the temperature ranges where they undergo a thermal dissociation, or melting. AdS/QCD models are know to provide an important tool for the calculation of hadronic masses, but in general are not consistent with the observation that decay constants of heavy vector mesons decrease with excitation level. It has recently been shown that this problem can be overcome using a soft wall background and introducing an extra energy parameter, through the calculation of correlation functions at a finite position of anti-de Sitter space. This approach leads to the evaluation of masses and decay constants of S wave quarkonium states with just one flavor dependent and one flavor independent parameter. Here we extend this more realistic model to finite temperatures and analyze the thermal behavior of the states 1S, 2S and 3S of bottomonium and charmonium. The corresponding spectral function exhibits a consistent picture for the melting of the states where, for each flavor, the higher excitations melt at lower temperatures. We estimate for these six states the energy ranges in which the heavy vector mesons undergo a transition from a well-defined peak in the spectral function to complete melting in the thermal medium. A very clear distinction between the heavy flavors emerges, with the bottomonium state Υ(1S) surviving a deconfinement transition at temperatures much larger than the critical deconfinement temperature of the medium. (orig.)
Plant viral vectors based on tobamoviruses.
Yusibov, V; Shivprasad, S; Turpen, T H; Dawson, W; Koprowski, H
1999-01-01
The potential of plant virus-based transient expression vectors is substantial. One objective is the production of large quantities of foreign peptides or proteins. At least one commercial group (Biosource Technologies) is producing large quantities of product in the field, has built factories to process truck-loads of material and soon expects to market virus-generated products. In the laboratory, large amounts of protein have been produced for structural or biochemical analyses. An important aspect of producing large amounts of a protein or peptide is to make the product easily purifiable. This has been done by attaching peptides or proteins to easily purified units such as virion particles or by exporting proteins to the apoplast so that purification begins with a highly enriched product. For plant molecular biology, virus-based vectors have been useful in identifying previously unknown genes by overexpression or silencing or by expression in different genotypes. Also, foreign peptides fused to virions are being used as immunogens for development of antisera for experimental use or as injected or edible vaccines for medical use. As with liposomes and microcapsules, plant cells and plant viruses are also expected to provide natural protection for the passage of antigen through the gastrointestinal tract. Perhaps the greatest advantage of plant virus-based transient expression vectors is their host, plants. For the production of large amounts of commercial products, plants are one of the most economical and productive sources of biomass. They also present the advantages of lack of contamination with animal pathogens, relative ease of genetic manipulation and the presence eukaryotic protein modification machinery.
Anisotropic cosmological solutions in massive vector theories
Heisenberg, Lavinia; Kase, Ryotaro; Tsujikawa, Shinji
2016-11-01
In beyond-generalized Proca theories including the extension to theories higher than second order, we study the role of a spatial component v of a massive vector field on the anisotropic cosmological background. We show that, as in the case of the isotropic cosmological background, there is no additional ghostly degrees of freedom associated with the Ostrogradski instability. In second-order generalized Proca theories we find the existence of anisotropic solutions on which the ratio between the anisotropic expansion rate Σ and the isotropic expansion rate H remains nearly constant in the radiation-dominated epoch. In the regime where Σ/H is constant, the spatial vector component v works as a dark radiation with the equation of state close to 1/3. During the matter era, the ratio Σ/H decreases with the decrease of v. As long as the conditions |Σ| ll H and v2 ll phi2 are satisfied around the onset of late-time cosmic acceleration, where phi is the temporal vector component, we find that the solutions approach the isotropic de Sitter fixed point (Σ = 0 = v) in accordance with the cosmic no-hair conjecture. In the presence of v and Σ the early evolution of the dark energy equation of state wDE in the radiation era is different from that in the isotropic case, but the approach to the isotropic value wDE(iso) typically occurs at redshifts z much larger than 1. Thus, apart from the existence of dark radiation, the anisotropic cosmological dynamics at low redshifts is similar to that in isotropic generalized Proca theories. In beyond-generalized Proca theories the only consistent solution to avoid the divergence of a determinant of the dynamical system corresponds to v = 0, so Σ always decreases in time.
On the vector model of angular momentum
Saari, Peeter
2016-09-01
Instead of (or in addition to) the common vector diagram with cones, we propose to visualize the peculiarities of quantum mechanical angular momentum by a completely quantized 3D model. It spotlights the discrete eigenvalues and noncommutativity of components of angular momentum and corresponds to outcomes of measurements—real or computer-simulated. The latter can be easily realized by an interactive worksheet of a suitable program package of algebraic calculations. The proposed complementary method of visualization helps undergraduate students to better understand the counterintuitive properties of this quantum mechanical observable.
Vector bundles on complex projective spaces
Okonek, Christian; Spindler, Heinz
1980-01-01
This expository treatment is based on a survey given by one of the authors at the Séminaire Bourbaki in November 1978 and on a subsequent course held at the University of Göttingen. It is intended to serve as an introduction to the topical question of classification of holomorphic vector bundles on complex projective spaces, and can easily be read by students with a basic knowledge of analytic or algebraic geometry. Short supplementary sections describe more advanced topics, further results, and unsolved problems.
Vector meson production above the resonance region
Energy Technology Data Exchange (ETDEWEB)
Marco Battaglieri
2005-04-01
The total and differential cross section for exclusive vector meson electro- and photoproduction above the resonance region (2
Hydrogen: an energy vector for the future?
Energy Technology Data Exchange (ETDEWEB)
His, St
2004-07-01
Used today in various industrial sectors including refining and chemicals, hydrogen is often presented as a promising energy vector for the transport sector. However, its balance sheet presents disadvantages as well as advantages. For instance, some of its physical characteristics are not very well adapted to transport use and hydrogen does not exist in pure form. Hydrogen technologies can offer satisfactory environmental performance in certain respects, but remain handicapped by costs too high for large-scale development. A great deal of research will be required to develop mass transport application. (author)
Vector blood velocity estimation in medical ultrasound
DEFF Research Database (Denmark)
Jensen, Jørgen Arendt; Gran, Fredrik; Udesen, Jesper
2006-01-01
Two methods for making vector velocity estimation in medical ultrasound are presented. All of the techniques can find both the axial and transverse velocity in the image and can be used for displaying both the correct velocity magnitude and direction. The first method uses a transverse oscillation...... in the ultrasound field to find the transverse velocity. In-vivo examples from the carotid artery are shown, where complex turbulent flow is found in certain parts of the cardiac cycle. The second approach uses directional beam forming along the flow direction to estimate the velocity magnitude. Using a correlation...
A sixth order averaged vector field method
Li, Haochen; Wang, Yushun; Qin, Mengzhao
2014-01-01
In this paper, based on the theory of rooted trees and B-series, we propose the concrete formulas of the substitution law for the trees of order =5. With the help of the new substitution law, we derive a B-series integrator extending the averaged vector field (AVF) method to high order. The new integrator turns out to be of order six and exactly preserves energy for Hamiltonian systems. Numerical experiments are presented to demonstrate the accuracy and the energy-preserving property of the s...
Evidence for further charmonium vector resonances
Institute of Scientific and Technical Information of China (English)
Eef van Beveren; George Rupp
2011-01-01
We discuss the shape of threshold signals in production cross sections of the reaction ee → DD, at the opening of the DD and ΛΛ channels. Furthermore, evidence for the ψ(3D), ψ(5S), ψ(4D), ψ(6S), ψ(5D), ψ(7S), ψ(6D), and ψ(8S) new charmonium vector resonances is presented, on the basis of data recently published by the BABAR Collaboration. Central masses and resonance widths are estimated. Confirmation of these resonances would be a huge step in lifting the precision level of hadron spectroscopy towards that of atomic spectroscopy, with far-reaching consequences for theory.
Adjuvants and vector systems for allergy vaccines.
Moingeon, Philippe; Lombardi, Vincent; Saint-Lu, Nathalie; Tourdot, Sophie; Bodo, Véronique; Mascarell, Laurent
2011-05-01
Allergen-specific immunotherapy represents a curative treatment of type I allergies. Subcutaneous immunotherapy is conducted with allergens adsorbed on aluminum hydroxide or calcium phosphate particles, whereas sublingual immunotherapy relies on high doses of soluble allergen without any immunopotentiator. There is a potential benefit of adjuvants enhancing regulatory and Th1 CD4+T cell responses during specific immunotherapy. Molecules affecting dendritic cells favor the induction of T regulatory cell and Th1 responses and represent valid candidate adjuvants for allergy vaccines. Furthermore, the interest in viruslike particles and mucoadhesive particulate vector systems, which may better address the allergen(s) to tolerogenic antigen-presenting cells, is documented.
ATLAS measurements of vector boson production
Chavez Barajas, Carlos Alberto; The ATLAS collaboration
2015-01-01
ATLAS measurements of vector boson production, inclusive and with associated jets in pp collisions in LHC Run1 will be presented. The results are compared to NLO Monte Carlo simulations and to NNLO QCD predictions corrected for NLO EW effects. The production of jets in association with a W or a Z boson is an important process to study QCD in a multiscale environment in pp collisions at the LHC. The production of heavy flavour in association with a W or Z boson is sensitive to the parton density functions and to the modeling heavyquark flavour production mechanisms.
Therapeutic globin gene delivery using lentiviral vectors.
Rivella, Stefano; Sadelain, Michel
2002-10-01
The severe hemoglobinopathies, including beta-thalassemia major and sickle cell anemia, are candidate diseases for a genetic treatment based on the transfer of a regulated globin gene in autologous hematopoietic stem cells. Two years ago, May et al reported that an optimized beta-globin transcription unit containing multiple proximal and distal regulatory elements harbored by a recombinant lentiviral vector could efficiently integrate into murine hematopoietic stem cells and express therapeutic levels of the human beta-globin gene. Here, we review the advantages afforded by lentivirus-mediated globin gene transfer and recent studies based on this strategy.
Malaria vectors of Timor-Leste
Directory of Open Access Journals (Sweden)
Frances Stephen P
2010-02-01
Full Text Available Abstract Background The island of Timor lies at the south-eastern edge of Indonesia on the boundary of the Oriental and Australian faunal regions. The country of Timor-Leste, which occupies the eastern part of the island, is malarious but anopheline faunal surveys and malaria vector incrimination date back to the 1960 s. Over the last decade the malaria vectors of south-east Asia and the south-west Pacific have been intensely studied using molecular techniques that can confirm identification within complexes of isomorphic species. The aim of this study is to accurately identify the Anopheles fauna of Timor-Leste using these techniques. Methods The survey was carried out over the period February to June 2001. Standard entomological techniques - human landing collections, larval collections and CO2 baited light traps - were used to collect anophelines from the main geographical regions: coastal plains, inland plains, and highlands. Specimens were processed for identification by morphology and genotyped for the ribosomal DNA ITS2 by restriction analysis and/or DNA sequencing. Phylogenetic relationship of Anopheles sundaicus and Anopheles subpictus individuals was also assessed using DNA sequences from the ITS2 and mitochondrial cytochrome-b. All specimens, other than those from larval surveys, were processed to detect the presence of the Plasmodium parasite circumsporozoite protein by ELISA for vector incrimination. Results Of 2,030 specimens collected, seven species were identified by morphology: Anopheles barbirostris, Anopheles aconitus, Anopheles annularis, Anopheles maculatus, Anopheles peditaeniatus, An. sundaicus and Anopheles vagus. These were confirmed by molecular analysis with the addition of Anopheles flavirostris and an unidentified species designated here as An. vagus genotype B. This latter species was morphologically similar to An. vagus and An. subpictus and is likely to be the An. subpictus described by other workers for Timor
[Climate- and vector-borne diseases
DEFF Research Database (Denmark)
Bygbjerg, I.C.; Schioler, K.L.; Konradsen, F.
2009-01-01
The predicted changes in climate have raised concerns that vector-borne diseases may emerge or expand in tempered regions. Malaria, leishmaniasis and tick-borne illnesses are discussed in terms of climate change and their endemic potential, especially in Denmark. While climate may play an important...... role in disease patterns, it is evident that transmission potential is governed by a complex of factors, including socio-economy, health-care capacity and ecology. In Denmark, malaria and leishmaniasis are unlikely to become public health problems, whereas the potential for tick-borne illnesses may...
Vector Control Based on SVPWM for ACIM
Directory of Open Access Journals (Sweden)
Zhu Jun
2013-05-01
Full Text Available To solve the large torque ripple and current harmonics, low DC bus voltage problems, a new control strategy is proposed for AC induction motor by using space vector pulse width modulation, so that the static and dynamic performance are improved. The system simulation experiment mode was established based on SVPWM to verify the effectiveness of the system control mode. It is showed that it can reduce the current ripple and torque ripple, improve the utilization of DC bus voltage. It means that the control strategy based SVPWM can improve dynamic and static performance effectively for the ACIM servo system.
A 4-vector formalism for classical mechanics
Güémez, Julio
2014-01-01
We present a matrix formalism, inspired by the Minkowski four-vectors of special relativity, useful to solve classical physics problems related to both mechanics and thermodynamics. The formalism turns out to be convenient to deal with exercises involving non-conservative forces and production or destruction of mechanical energy. On the other hand, it provides a framework to treat straightforwardly changes of inertial reference frames, since it embodies the Principle of Relativity. We apply the formalism to a few cases to better show how it works.
Differential geometry of complex vector bundles
Kobayashi, Shoshichi
2014-01-01
Holomorphic vector bundles have become objects of interest not only to algebraic and differential geometers and complex analysts but also to low dimensional topologists and mathematical physicists working on gauge theory. This book, which grew out of the author's lectures and seminars in Berkeley and Japan, is written for researchers and graduate students in these various fields of mathematics. Originally published in 1987. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeto
Institute of Scientific and Technical Information of China (English)
无
2005-01-01
Vinten Vector 60云台适用于新型演播室型和实况转播型数字摄像机、长镜头或提示器组合。该产品结合Vinten最新平衡补偿技术与润滑阻尼机构，提供当今摄像师所要求的“镜头末端”（End of the Lens）控制。
Trópicos, microbios y vectores
2002-01-01
Analizamos el modo como los investigadores argentinos y brasileños, de fines del XIX e inicios del XX, construyeron sus programas de investigación referidos a las enfermedades tropicales. Aun cuando la higiene brasileña y argentina fueron herederas directas de los programas y principios pasteurianos, Brasil enfrentó sus problemas sanitarios con un nuevo programa de investigación donde se integraban la bacteriología, la parasitología y la preocupación con los vectores. Argentina, por su parte,...
Cosmological aspects of a vector field model
Sadatian, S Davood
2012-01-01
We have studied a DGP-inspired braneworld scenario where the idea of Lorentz invariance violation has been combined into a specifying preferred frame that embed a dynamical normal vector field to brane. We propose the Lorentz violating DGP brane models with enough parameters can explain crossing of phantom divide line. Also we have considered the model for proper cosmological evolution that is according to the observed behavior of the equation of state. In other view point, we have described a Rip singularity solution of model that occur in this model.
COMPUTATION OF VECTOR VALUED BLENDING RATIONAL INTERPOLANTS
Institute of Scientific and Technical Information of China (English)
檀结庆
2003-01-01
As we know, Newton's interpolation polynomial is based on divided differ-ences which can be calculated recursively by the divided-difference scheme while Thiele'sinterpolating continued fractions are geared towards determining a rational functionwhich can also be calculated recursively by so-called inverse differences. In this paper,both Newton's interpolation polynomial and Thiele's interpolating continued fractionsare incorporated to yield a kind of bivariate vector valued blending rational interpolantsby means of the Samelson inverse. Blending differences are introduced to calculate theblending rational interpolants recursively, algorithm and matrix-valued case are dis-cussed and a numerical example is given to illustrate the efficiency of the algorithm.
Máquinas de Vectores Soporte Adaptativas
Grinblat, Guillermo L.; Ceccatto, Hermenegildo Alejandro
2007-01-01
Se propone un método de clasificación adaptativo capaz de aprender un concepto y seguir su evolución temporal como consecuencia de cambios lentos en sistemas evolutivos. Para ello se realiza una modificación del clasificador SVM (máquina de vectores soporte), consistente en usar múltiples hiperplanos válidos en pequeñas localidades temporales (ventanas) para realizar la clasificación. A diferencia de otras propuestas de este tipo en la literatura, en este caso se realiza un aprendizaje de tod...
Vector condensate model of electroweak interactions
Cynolter, G
1996-01-01
Motivated by the fact that the Higgs is not seen we proposed a version of the standard model where the scalar doublet is replaced by a doublet of vector fields. The neutral member of the doublet forms a nonvanishing condensate generating masses for the weak gauge bosons. The phenomenology of the model is studied in high energy e+e- colliders and in the formalism of the parameters S,T,U. The experiments recquire heavy new particles at least 200 GeV which can be produced at the next generation of colliders.
Use of HIV as a gene transfer vector.
Pluta, Krzysztof; Kacprzak, Magdalena Marta
2009-01-01
Despite the extensive research efforts over the past 25 years that have focused on HIV, there is still no cure for AIDS. However, tremendous progress in the understanding of the structure and biology of the HIV virus led to the development of safe and potent HIV-based transgene delivery vectors. These genetic vehicles are referred to as lentiviral vectors. They appear to be better suited for particular applications, such as transgene delivery into stem cells, compared to other viral- and non-viral vectors. This is because Lentivirus-based vectors can efficiently infect nondividing and slowly dividing cells. In the present review article, the current state of understanding of HIV-1 is discussed and the main characteristics that had an impact on vector design are outlined. A historical view on the vector concept is presented to facilitate discussion of recent results in vector engineering in a broader context. Subsequently, a state of the art overview concerning vector construction and vector production is given. This review also touches upon the subject of lentiviral vector safety and related topics that can be helpful in addressing this issue are discussed. Finally, examples of Lentivirus-based gene delivery systems and their applications are presented, with emphasis on animal transgenesis and human gene therapy.
Environmental management: a re-emerging vector control strategy.
Ault, S K
1994-01-01
Vector control may be accomplished by environmental management (EM), which consists of permanent or long-term modification of the environment, temporary or seasonal manipulation of the environment, and modifying or changing our life styles and practices to reduce human contact with infective vectors. The primary focus of this paper is EM in the control of human malaria, filariasis, arboviruses, Chagas' disease, and schistosomiasis. Modern EM developed as a discipline based primarily in ecologic principles and lessons learned from the adverse environmental impacts of rural development projects. Strategies such as the suppression of vector populations through the provision of safe water supplies, proper sanitation, solid waste management facilities, sewerage and excreta disposal systems, water manipulation in dams and irrigation systems, vector diversion by zooprophylaxis, and vector exclusion by improved housing, are discussed with appropriate examples. Vectors of malaria, filariasis, Chagas' disease, and schistosomiasis have been controlled by drainage or filling aquatic breeding sites, improved housing and sanitation, the use of expanded polystyrene beads, zooprophylaxis, or the provision of household water supplies. Community participation has been effective in the suppression of dengue vectors in Mexico and the Dominican Republic. Alone or combined with other vector control methods, EM has been proven to be a successful approach to vector control in a number of places. The future of EM in vector control looks promising.
Transient gene expression mediated by integrase-defective retroviral vectors.
Yu, Seung Shin; Dan, Kazuyuki; Chono, Hideto; Chatani, Emi; Mineno, Junichi; Kato, Ikunoshin
2008-04-18
Nonintegrating retroviral vectors were produced from a Moloney murine leukemia virus (MoMLV)-based retroviral vector system by introducing a point mutation into the integrase (IN) gene of the packaging plasmid. The efficacy of IN-defective retroviral vectors was measured through the transient expression of ZsGreen or luciferase in human cell lines. The IN-defective retroviral vectors could transduce target cells efficiently, but their gene expression was transient and lower than that seen with the integrating vectors. IN-defective retroviral vector gene expression decreased to background levels in fewer than 10 days. Southern blot analysis of transduced K562 cells confirmed the loss of a detectable vector sequence by 15 days. The residual integration activity of the IN-defective vector was 1000- to 10,000-fold lower than that of the integrating vector. These results demonstrate that the IN-defective retroviral vectors can provide a useful tool for efficient transient gene expression targeting of primary hematopoietic stem cells and lymphoid cells.
Chikungunya virus and its mosquito vectors.
Higgs, Stephen; Vanlandingham, Dana
2015-04-01
Chikungunya virus (CHIKV), a mosquito-borne alphavirus of increasing public health significance, has caused large epidemics in Africa and the Indian Ocean basin; now it is spreading throughout the Americas. The primary vectors of CHIKV are Aedes (Ae.) aegypti and, after the introduction of a mutation in the E1 envelope protein gene, the highly anthropophilic and geographically widespread Ae. albopictus mosquito. We review here research efforts to characterize the viral genetic basis of mosquito-vector interactions, the use of RNA interference and other strategies for the control of CHIKV in mosquitoes, and the potentiation of CHIKV infection by mosquito saliva. Over the past decade, CHIKV has emerged on a truly global scale. Since 2013, CHIKV transmission has been reported throughout the Caribbean region, in North America, and in Central and South American countries, including Brazil, Columbia, Costa Rica, El Salvador, French Guiana, Guatemala, Guyana, Nicaragua, Panama, Suriname, and Venezuela. Closing the gaps in our knowledge of driving factors behind the rapid geographic expansion of CHIKV should be considered a research priority. The abundance of multiple primate species in many of these countries, together with species of mosquito that have never been exposed to CHIKV, may provide opportunities for this highly adaptable virus to establish sylvatic cycles that to date have not been seen outside of Africa. The short-term and long-term ecological consequences of such transmission cycles, including the impact on wildlife and people living in these areas, are completely unknown.
Behavioural biology of Chagas disease vectors
Directory of Open Access Journals (Sweden)
Claudio Ricardo Lazzari
2013-01-01
Full Text Available Many arthropod species have adopted vertebrate blood as their main food source. Blood is rich in nutrients and, except for the presence of parasites, sterile. However, this food source is not freely available, nor is obtaining it devoid of risk. It circulates inside vessels hidden underneath the skin of mobile hosts that are able to defend themselves and even predate the insects that try to feed on them. Thus, the haematophagous lifestyle is associated with major morphological, physiological and behavioural adaptations that have accumulated throughout the evolutionary history of the various lineages of blood-sucking arthropods. These adaptations have significant consequences for the evolution of parasites as well as for the epidemiology of vector-transmitted diseases. In this review article, we analyse various aspects of the behaviour of triatomine bugs to illustrate how each behavioural trait represents a particular adaptation to their close association with their hosts, which may easily turn into predators. Our aim is to offer to the reader an up-to-date integrative perspective on the behaviour of Chagas disease vectors and to propose new research avenues to encourage both young and experienced colleagues to explore this aspect of triatomine biology.
Light Vector Mesons in the Nuclear Medium
Wood, M H; Weygand, D P; Djalali, C; Tur, C; Mosel, U; Mühlich, P; Adams, G; Amaryan, M J; Ambrozewicz, P; Anghinolfi, M; Asryan, G; Avakian, H; Bagdasaryan, H; Baillie, N; Ball, J P; Baltzell, N A; Barrow, S; Battaglieri, M; Bedlinskiy, I; Bektasoglu, M; Bellis, M; Benmouna, N; Berman, B L; Biselli, A S; Blaszczyk, L; Bouchigny, S; Boiarinov, S; Bradford, R; Branford, D; Briscoe, W J; Brooks, W K; Burkert, V D; Butuceanu, C; Calarco, J R; Careccia, S L; Carman, D S; Carnahan, B; Casey, L; Chen, S; Cheng, L; Cole, P L; Collins, P; Coltharp, P; Crabb, D; Crannell, H; Credé, V; Cummings, J P; Dashyan, N; De Vita, R; De Sanctis, E; Degtyarenko, P V; Denizli, H; Dennis, L; Deur, A; Dharmawardane, K V; Dickson, R; Dodge, G E; Doughty, D; Dugger, M; Dytman, S; Dzyubak, O P; Egiyan, H; Egiyan, K S; El Fassi, L; Elouadrhiri, L; Eugenio, P; Fedotov, G; Feldman, G; Feuerbach, R J; Fradi, A; Funsten, H; Garçon, M; Gavalian, G; Gilfoyle, G P; Giovanetti, K L; Girod, F X; Goetz, J T; Gordon, C I O; Gothe, R W; Griffioen, K A; Guidal, M; Guler, N; Guo, L; Gyurjyan, V; Hadjidakis, C; Hafidi, K; Hakobyan, H; Hakobyan, R S; Hanretty, C; Hardie, J; Hassall, N; Hersman, F W; Hicks, K; Hleiqawi, I; Holtrop, M; Hyde-Wright, C E; Ilieva, Y; Ireland, D G; Ishkhanov, B S; Isupov, E L; Ito, M M; Jenkins, D; Jo, H S; Johnstone, J R; Joo, K; Jüngst, H G; Kalantarians, N; Kellie, J D; Khandaker, M; Khetarpal, P; Kim, W; Klein, A; Klein, F J; Klimenko, A V; Kossov, M; Krahn, Z; Kramer, L H; Kubarovski, V; Kühn, J; Kuhn, S E; Kuleshov, S V; Lachniet, J; Laget, J M; Langheinrich, J; Lawrence, D; Ji, Li; Livingston, K; Lu, H Y; MacCormick, M; Markov, N; Mattione, P; McAleer, S; McKinnon, B; McNabb, J W C; Mecking, B A; Mehrabyan, S; Melone, J J; Mestayer, M D; Meyer, C A; Mibe, T; Mikhailov, K; Minehart, R; Mirazita, M; Miskimen, R; Mokeev, V; Moriya, K; Morrow, S A; Moteabbed, M; Müller, J; Munevar, E; Mutchler, G S; Nadel-Turonski, P; Niccolai, S; Niculescu, G; Niculescu, I; Niczyporuk, B B; Niroula, M R; Niyazov, R A; Nozar, M; Osipenko, M; Ostrovidov, A I; Park, K; Pasyuk, E; Paterson, C; Anefalos Pereira, S; Pierce, J; Pivnyuk, N; Pocanic, D; Pogorelko, O; Pozdniakov, S; Preedom, B M; Price, J W; Prok, Y; Protopopescu, D; Raue, B A; Riccardi, G; Ricco, G; Ripani, M; Ritchie, B G; Ronchetti, F; Rosner, G; Rossi, P; Sabati, F; Salamanca, J; Salgado, C; Santoro, J P; Sapunenko, V; Schumacher, R A; Serov, V S; Sharabyan, Yu G; Sharov, D; Shvedunov, N V; Smith, E S; Smith, L C; Sober, D I; Sokhan, D; Stavinsky, A; Stepanyan, S; Stepanyan, S S; Stokes, B E; Stoler, P; Strakovsky, I I; Strauch, S; Taiuti, M; Tedeschi, D J; Tkabladze, A; Tkachenko, S; Todor, L; Ungaro, M; Vineyard, M F; Vlassov, A V; Watts, D P; Weinstein, L B; Williams, M; Wolin, E; Yegneswaran, A; Zana, L; Zhang, B; Zhang, J; Zhao, B; Zhao, Z W
2008-01-01
The light vector mesons ($\\rho$, $\\omega$, and $\\phi$) were produced in deuterium, carbon, titanium, and iron targets in a search for possible in-medium modifications to the properties of the $\\rho$ meson at normal nuclear densities and zero temperature. The vector mesons were detected with the CEBAF Large Acceptance Spectrometer (CLAS) via their decays to $e^{+}e^{-}$. The rare leptonic decay was chosen to reduce final-state interactions. A combinatorial background was subtracted from the invariant mass spectra using a well-established event-mixing technique. The $\\rho$ meson mass spectrum was extracted after the $\\omega$ and $\\phi$ signals were removed in a nearly model-independent way. Comparisons were made between the $\\rho$ mass spectra from the heavy targets ($A > 2$) with the mass spectrum extracted from the deuterium target. With respect to the $\\rho$-meson mass, we obtain a small shift compatible with zero. Also, we measure widths consistent with standard nuclear many-body effects such as collisional...
Ticks as vectors: taxonomy, biology and ecology.
Estrada-Peña, A
2015-04-01
Ticks are prominent parasites and competent vectors of pathogens that affect both humans and animals. This review outlines and illustrates the main features of the morphology of ticks of the families Ixodidae and Argasidae, and summarises the basic components of their life cycles. It focuses mainly on development processes and mortality among tick populations so as to provide an overview of how they are regulated in nature and how pathogens can be transmitted under such a framework. The effects of the weather on these life cycles are reviewed. The author also examines how landscape structure and biotic factors, such as the presence and abundance of hosts, may shape the density of tick populations. The uncertainty inherent in dealing with the transmission of pathogens by ticks is highlighted; this results from the sometimes complex relationships among the vectors, the climate and the presence and density of host populations. The need to obtain reliable field estimations of such relationships before drawing conclusions about the effects of the isolated components of the system is stressed. A section is devoted to addressing the expected (and not yet totally understood) effects of trends in climate on the spread of ticks, and how these can be analysed and tracked.
Dark matter monopoles, vectors and photons
Khoze, Valentin V
2014-01-01
In a secluded dark sector which is coupled to the Standard Model via a Higgs portal interaction we arrange for the existence of 't Hooft-Polyakov magnetic monopoles and study their implications for cosmology. We point out that a dark sector which can accommodate stable monopoles will also contain massless dark photons gamma' as well as charged massive vector bosons W'. The dark matter in this scenario will be a combination of magnetically and electrically charged species under the unbroken U(1) subgroup of the dark sector. We estimate the cosmological production rate of monopoles and the rate of monopole-anti-monopole annihilation and conclude that monopoles with masses of few hundred TeV or greater, can produce sizeable contributions to the observed dark matter relic density. We scan over the parameter space and compute the relic density for monopoles and vector bosons. Turning to the dark photon radiation, we compute their contribution to the measured density of relativistic particles Neff and also apply ob...
Improved NYVAC-based vaccine vectors.
Directory of Open Access Journals (Sweden)
Karen V Kibler
Full Text Available While as yet there is no vaccine against HIV/AIDS, the results of the phase III Thai trial (RV144 have been encouraging and suggest that further improvements of the prime/boost vaccine combination of a poxvirus and protein are needed. With this aim, in this investigation we have generated derivatives of the candidate vaccinia virus vaccine vector NYVAC with potentially improved functions. This has been achieved by the re-incorporation into the virus genome of two host range genes, K1L and C7L, in conjunction with the removal of the immunomodulatory viral molecule B19, an antagonist of type I interferon action. These novel virus vectors, referred to as NYVAC-C-KC and NYVAC-C-KC-ΔB19R, have acquired relevant biological characteristics, giving higher levels of antigen expression in infected cells, replication-competency in human keratinocytes and dermal fibroblasts, activation of selective host cell signal transduction pathways, and limited virus spread in tissues. Importantly, these replication-competent viruses have been demonstrated to maintain a highly attenuated phenotype.
Holographic Picture of Heavy Vector Meson Melting
Braga, Nelson R F; Diles, Saulo
2016-01-01
The fraction of heavy vector mesons produced in a heavy ion collision, as compared to a proton proton collision, serves as an important indication of the formation of a thermal medium, the quark gluon plasma. This sort of analysis strongly depends on understanding the thermal effects of a medium like the plasma on the states of heavy mesons. In particular, it is crucial to know the temperature ranges where they undergo a thermal dissociation, or melting. AdS/QCD models are know to provide an important tool for the calculation of hadronic masses, but in general are not consistent with the observation that decay constants of heavy vector mesons decrease with excitation level. It has recently been shown that this problem can be overcome using a soft wall background and introducing an extra energy parameter, through the calculation of correlation functions at a finite position of anti-de Sitter space. This approach leads to the evaluation of masses and decay constants of S wave quarkonium states with just one fla...
Acoustic communication in insect disease vectors
Directory of Open Access Journals (Sweden)
Felipe de Mello Vigoder
2013-01-01
Full Text Available Acoustic signalling has been extensively studied in insect species, which has led to a better understanding of sexual communication, sexual selection and modes of speciation. The significance of acoustic signals for a blood-sucking insect was first reported in the XIX century by Christopher Johnston, studying the hearing organs of mosquitoes, but has received relatively little attention in other disease vectors until recently. Acoustic signals are often associated with mating behaviour and sexual selection and changes in signalling can lead to rapid evolutionary divergence and may ultimately contribute to the process of speciation. Songs can also have implications for the success of novel methods of disease control such as determining the mating competitiveness of modified insects used for mass-release control programs. Species-specific sound “signatures” may help identify incipient species within species complexes that may be of epidemiological significance, e.g. of higher vectorial capacity, thereby enabling the application of more focussed control measures to optimise the reduction of pathogen transmission. Although the study of acoustic communication in insect vectors has been relatively limited, this review of research demonstrates their value as models for understanding both the functional and evolutionary significance of acoustic communication in insects.
Residual stresses and vector hysteresis modeling
Energy Technology Data Exchange (ETDEWEB)
Ktena, Aphrodite, E-mail: aktena@teiste.gr
2016-04-01
Residual stresses in magnetic materials, whether the result of processing or intentional loading, leave their footprint on macroscopic data, such hysteresis loops and differential permeability measurements. A Preisach-type vector model is used to reproduce the phenomenology observed based on assumptions deduced from the data: internal stresses lead to smaller and misaligned grains, hence increased domain wall pinning and angular dispersion of local easy axes, favouring rotation as a magnetization reversal mechanism; misaligned grains contribute to magnetostatic fields opposing the direction of the applied field. The model is using a vector operator which accounts for both reversible and irreversible processes; the Preisach concept for interactions for the role of stress related demagnetizing fields; and a characteristic probability density function which is constructed as a weighed sum of constituent functions: the material is modeled as consisting of various subsystems, e.g. reversal mechanisms or areas subject to strong/weak long range interactions and each subsystem is represented by a constituent probability density function. Our assumptions are validated since the model reproduces the hysteresis loops and differential permeability curves observed experimentally and calculations involving rotating inputs at various residual stress levels are consistent and in agreement with experimental evidence.
Strangeness Vector and Axial-Vector Form Factors of the Nucleon
Directory of Open Access Journals (Sweden)
Pate Stephen
2014-03-01
Full Text Available A revised global fit of electroweak ep and vp elastic scattering data has been performed, with the goal of determining the strange quark contribution to the vector and axial-vector form factors of the nucleon in the momentum-transfer range 0 < Q2 < 1 GeV2. The two vector (electric and magnetic form factors GsE(Q2 and GsM(Q2 are strongly constrained by ep elastic scattering data, while the major source of information on the axial-vector form factor GsA(Q2 is vp scattering data. Combining the two kinds of data into a single global fit makes possible additional precision in the determination of these form factors, and provides a unique way to determine the strange quark contribution to the nucleon spin, ΔS , independently of leptonic deep-inelastic scattering. The fit makes use of data from the BNL-E734, SAMPLE, HAPPEx, G0, and PVA4 experiments; we will also compare the result of the fit with recent data from MiniBooNE, and anticipate how this fit can be improved when new data from MicroBooNE become available.
Elbourne, A.; de Haan, J.
2009-01-01
Using the vector autoregressive methodology, we present estimates of monetary transmission for five new EU member countries in Central and Eastern Europe with more or less flexible exchange rates. We select sample periods to estimate over the longest possible period that can be considered as a singl
QUEUEING NETWORKS WITH STRING TRANSITIONS OF MIXED VECTOR ADDITIONS AND VECTOR REMOVALS
Institute of Scientific and Technical Information of China (English)
Richard J. Boucherie; Xiuli Chao
2001-01-01
Product form queueing networks with string transitions have been studied in the literature as a model incorporating several features of the existing networks. Thatmodel includes state-dependent transition rates at the cost of a restrictive form of the string transitions: First a sequence of nonnegative vectors is removed, and then a sequence of nonnegative vectors is added to the network state. Such a transition structure excludes, for example, networks with positive and negative signals recently studied in the literature. This paper extends the string transition networks to allow transitions of mixed vector additions and vector removals, and it includes assembly-transfer networks as well as networks with negative and positive signals as special cases. Assuming that the transition rates are independent of the network state except at the boundaries, we obtain general modifications for the string transition network under which it possesses a product form equilibrium distribution. T he network is shown to satisfy a class of local balance as expressed by a set of traffic equations.
Reducing vector-borne disease by empowering farmers in integrated vector management
Berg, van den H.; Hildebrand, von A.; Ragunathan, V.; Das, P.K.
2007-01-01
PROBLEM: Irrigated agriculture exposes rural people to health risks associated with vector-borne diseases and pesticides used in agriculture and for public health protection. Most developing countries lack collaboration between the agricultural and health sectors to jointly address these problems. A
Bounds on the tau and muon neutrino vector and axial vector charge radius
Hirsch, M; Restrepo, D A; Hirsch, Martin; Nardi, Enrico; Restrepo, Diego
2003-01-01
A Majorana neutrino is characterized by just one flavor diagonal electromagnetic form factor: the anapole moment, that in the static limit corresponds to the axial vector charge radius . Experimental information on this quantity is scarce, especially in the case of the tau neutrino. We present a comprehensive analysis of the available data on the single photon production process $e^+e^- -> \
Rademaker, Hendrik Jan
2007-01-01
Current generation adenoviral vectors (Ads) are not suitable for those gene therapy approaches that require long-term gene expression. This is due to their high immunogenicity and transient gene expression in fast dividing tissue. The development of gutless Ads, also known as helper-dependent Ads, i
Vector-borne disease problems in rapid urbanization: new approaches to vector control.
Knudsen, A B; Slooff, R
1992-01-01
Owing to population growth, poor levels of hygiene, and increasing urban poverty, the urban environment in many developing countries is rapidly deteriorating. Densely packed housing in shanty towns or slums and inadequate drinking-water supplies, garbage collection services, and surface-water drainage systems combine to create favourable habitats for the proliferation of vectors and reservoirs of communicable diseases. As a consequence, vector-borne diseases such as malaria, lymphatic filariasis and dengue are becoming major public health problems associated with rapid urbanization in many tropical countries. The problems in controlling these diseases and eliminating vectors and pests can be resolved by decision-makers and urban planners by moving away from the concept of "blanket" applications of pesticides towards integrated approaches. Sound environmental management practices and community education and participation form the mainstay of some of the most outstanding successes in this area. On the basis of these examples, it is argued that the municipal authorities need to apply a flexible methodology, which must be based on the possibilities of mobilizing community resources, with minimal reliance on routine pesticidal spraying. In this way, vector control becomes a by-product of human development in the city environment. This is now a true challenge.
Vector correlations in rotationally inelastic molecular collisions
Energy Technology Data Exchange (ETDEWEB)
Lemeshko, Mikhail
2011-04-13
The thesis presents an analytic model that describes scalar and vector properties of molecular collisions, both field-free and in fields. The model is based on the sudden approximation and treats molecular scattering as the Fraunhofer diffraction of matter waves from the hard-core part of the interaction potential. The theory has no fitting parameters and is inherently quantum, rendering fully state- and energy-resolved scattering amplitudes and all the quantities that unfold from them in analytic form. This allows to obtain complex polarization moments inherent to quantum stereodynamics, and to account for interference and other non-classical effects. The simplicity and analyticity of the model paves a way to understanding the origin of the features observed in experiment and exact computations, such as the angular oscillations in the state-to-state differential cross sections and the polarization moments, the rotational-state dependent variation of the integral cross sections, and change of these quantities as a function of the applied field. The theory was applied to study the k - k{sup '} vector correlation (differential cross section) for the following collision systems: Ar-NO(X{sup 2}{pi}) and Ne-OCS(X{sup 1}{sigma}) in an electrostatic field, Na{sup +}-N{sub 2}(X{sup 1}{sigma}) in a laser field, and He-CaH({sup 2}{sigma}), He-O{sub 2}(X{sup 3}{sigma}), and He-OH(X{sup 2}{pi}) in a magnetic field. The model was able to reproduce the behavior of the differential cross sections and their variation with field strength. Combining the Fraunhofer model with the quantum theory of vector correlations made it possible to study three- and four-vector properties. The model results for the k-k{sup '}-j{sup '} vector correlation in Ar-NO(X{sup 2}{pi}) and He-NO(X{sup 2}{pi}) scattering were found to be in good agreement with experiment and exact computations. This allowed to demonstrate that the stereodynamics of such collisions is contained solely in the
ON THE ISSUE OF VECTOR CONTROL OF THE ASYNCHRONOUS MOTORS
Directory of Open Access Journals (Sweden)
B. I. Firago
2015-01-01
Full Text Available The paper considers the issue of one of the widespread types of vector control realization for the asynchronous motors with a short-circuited rotor. Of all more than 20 vector control types known presently, the following are applied most frequently: direct vector control with velocity pickup (VP, direct vector control without VP, indirect vector control with VP and indirect vector control without VP. Despite the fact that the asynchronous-motor indirect vector control without VP is the easiest and most spread, the absence of VP does not allow controlling the motor electromagnetic torque at zero velocity. This is the reason why for electric motor drives of such requirements they utilize the vector control with a velocity transducer. The systems of widest dissemination became the direct and indirect vector control systems with X-axis alignment of the synchronously rotating x–y-coordinate frame along the rotor flux-linkage vector inasmuch as this provides the simplest correlations for controlling variables. Although these two types of vector control are well presented in literature, a number of issues concerning their realization and practical application require further elaboration. These include: the block schemes adequate representation as consisted with the modern realization of vector control and clarification of the analytical expressions for evaluating the regulator parameters.The authors present a technique for evaluating the dynamics of an asynchronous electric motor drive with direct vector control and x-axis alignment along the vector of rotor flux linkage. The article offers a generalized structure of this vector control type with detailed description of its principal blocks: controlling system, frequency converter, and the asynchronous motor.The paper presents a direct vector control simulating model developed in the MatLab environment on the grounds of this structure. The authors illustrate the described technique with the results
Fauzi, Ahmad; Ratna Kawuri, Kunthi; Pratiwi, Retno
2017-01-01
Researchers of students’ conceptual change usually collects data from written tests and interviews. Moreover, reports of conceptual change often simply refer to changes in concepts, such as on a test, without any identification of the learning processes that have taken place. Research has shown that students have difficulties with vectors in university introductory physics courses and high school physics courses. In this study, we intended to explore students’ understanding of one-dimensional and two-dimensional vector in multi perspective views. In this research, we explore students’ understanding through test perspective and interviews perspective. Our research study adopted the mixed-methodology design. The participants of this research were sixty students of third semester of physics education department. The data of this research were collected by testand interviews. In this study, we divided the students’ understanding of one-dimensional vector and two-dimensional vector in two categories, namely vector skills of the addition of one-dimensionaland two-dimensional vector and the relation between vector skills and conceptual understanding. From the investigation, only 44% of students provided correct answer for vector skills of the addition of one-dimensional and two-dimensional vector and only 27% students provided correct answer for the relation between vector skills and conceptual understanding.
Hyvärinen, Anna; Yongabi, Felicitas; Mäkinen, Kimmo; Wahlfors, Jarmo; Pellinen, Riikka
2013-08-01
Sindbis vectors have shown remarkable antitumor efficacy and tumor-targeting capacity in animal models and hold promise for cancer therapy. Different packaging systems are used to produce propagation-incompetent Sindbis vectors. However, the vectors produced using either DH-BB single helper RNA or split helper RNA can spread in permissive cell cultures. We investigated the mechanisms of vector spreading and show, here, that recombination occurs between the replicon and DH-BB helper RNA, leading to formation of the full-length virus genome. Split helper RNA may not completely prevent wild-type reversion, although the frequency is greatly reduced. Contrary to propagation of Sindbis DH-BB vectors, Sindbis split helper vectors were frequently able to spread without cytopathic effect (CPE), a feature that was linked to wild-type reversion. Our results support the hypothesis that the non-cytopathic local spreading constantly observed with Sindbis split helper vector results from unspecific packaging of helper RNAs into vector particles and co-infection with particles containing replicon and helper RNAs. Several malignant cell lines with defective interferon responses were found to be permissive for non-cytopathic spreading of the Sindbis split helper vector. Interferon-α suppressed the spreading providing a possible option to control the vector.
Antigenic structures stably expressed by recombinant TGEV-derived vectors.
Becares, Martina; Sanchez, Carlos M; Sola, Isabel; Enjuanes, Luis; Zuñiga, Sonia
2014-09-01
Coronaviruses (CoVs) are positive-stranded RNA viruses with potential as immunization vectors, expressing high levels of heterologous genes and eliciting both secretory and systemic immune responses. Nevertheless, its high recombination rate may result in the loss of the full-length foreign gene, limiting their use as vectors. Transmissible gastroenteritis virus (TGEV) was engineered to express porcine reproductive and respiratory syndrome virus (PRRSV) small protein domains, as a strategy to improve heterologous gene stability. After serial passage in tissue cultures, stable expression of small PRRSV protein antigenic domains was achieved. Therefore, size reduction of the heterologous genes inserted in CoV-derived vectors led to the stable expression of antigenic domains. Immunization of piglets with these TGEV vectors led to partial protection against a challenge with a virulent PRRSV strain, as immunized animals showed reduced clinical signs and lung damage. Further improvement of TGEV-derived vectors will require the engineering of vectors with decreased recombination rate.
Two-dimensional magnetostriction under vector magnetic characteristic
Wakabayashi, D.; Enokizono, M.
2015-05-01
This paper presents two-dimensional magnetostriction of electrical steel sheet under vector magnetic characteristic. In conventional measurement method using Single Sheet Tester, the magnetic flux density, the magnetic field strength, and the magnetostriction have been measured in one direction. However, an angle between the magnetic flux density vector and the magnetic field strength vector exists because the magnetic property is vector quantity. An angle between the magnetic flux density vector and the direction of maximum magnetostriction also exists. We developed a new measurement method, which enables measurement of these angles. The vector magnetic characteristic and the two-dimensional magnetostriction have been measured using the new measurement method. The BH and Bλ curves considering the angles are shown in this paper. The analyzed results considering the angles are also made clear.
HORIZONTAL LAPLACE OPERATOR IN REAL FINSLER VECTOR BUNDLES
Institute of Scientific and Technical Information of China (English)
无
2008-01-01
A vector bundle F over the tangent bundle TM of a manifold M is said to be a Finsler vector bundle if it is isomorphic to the pull-back π*E of a vector bundle E over M([1]). In this article the authors study the h-Laplace operator in Finsler vector bundles.An h-Laplace operator is defined, first for functions and then for horizontal Finsler forms on E. Using the h-Laplace operator, the authors define the h-harmonic function and h-harmonic horizontal Finsler vector fields, and furthermore prove some integral formulas for the h-Laplace operator, horizontal Finsler vector fields, and scalar fields on E.
Construction and expression of recombined human AFP eukaryotic expression vector
Institute of Scientific and Technical Information of China (English)
Li-Wang Zhang; Yang-Lin Pan; Stephen M Festein; Jun Ren; Liang Zhang; Hong-Mei Zhang; Bin Jin; Bo-Rong Pan; Xiao-Ming Si; Yan-Jun Zhang; Zhong-Hua Wang
2003-01-01
AIM: To construct a recombined human AFP eukaryotic expression vector for the purpose of gene therapy and target therapy of hepatocellular carcinoma (HCC).METHODS: The full length AFP-cDNA of prokaryotic vector was digested, and subcloned to the multi-clony sites of the eukaryotic vector. The constructed vector was confirmed by enzymes digestion and electrophoresis, and the product expressed was detected by electrochemiluminescence and immunofluorescence methods.RESULTS: The full length AFP-cDNA successfully cloned to the eukaryotic vector through electrophoresis, 0.9723 IU/ml AFP antigen was detected in the supernatant of AFPCHO by electrochemiluminescence method. Compared with the control groups, the differences were significant (P＜0.05).AFP antigen molecule was observed in the plasma of AFPCHO by immunofluorescence staining.CONCLUSION: The recombined human AFP eukaryotic expression vector can express in CHO cell line. It provides experimental data for gene therapy and target therapy of hepatocellular carcinoma.
Institute of Scientific and Technical Information of China (English)
陶鹏; 黄小云; 李必元; 王五宏; 岳智臣; 雷娟利; 钟新民
2015-01-01
获得叶绿体基因组定点整合表达载体是开展结球甘蓝叶绿体基因组的遗传转化研究的第一步。本研究克隆了CMS结球甘蓝的抗冻蛋白K IN基因，发现该基因定位于结球甘蓝的2号染色体上。通过构建中间载体pKA和pAI，将K IN基因的编码区构建到了CMS结球甘蓝叶绿体基因组定点整合表达载体pIKAA中。该载体以TrnA 和TrnI基因片段作为同源整合片段，能整合到CMS结球甘蓝叶绿体基因组中。此外，该载体是双顺反子形式的，即在转录的单条mRNA上，同时包含了K IN和aadA 基因编码区。将pIKAA转化到大肠杆菌中，结果显示转化有该载体的大肠杆菌能够在含有氨苄青霉素(AMP)和壮观霉素(SPEC)的固体LB平板中生长。研究结果可为后期CMS结球甘蓝叶绿体基因组的遗传转化体系的建立奠定基础。%To construct chloroplast site-specific integration expression vector is the first step for carrying on genetic transformation of cabbage chloroplast genome (Brassica oleracea L. var. capitata L.). In this study, antifree-ze protein KIN gene was cloned from cytoplasmic male sterility (CMS) cabbage (Brassica oleracea L. var. capitata L.), and was located in 2 chromosome in B. oleracea genome. By constructing the intermediate vector pKA and pAI, coding region of KIN gene was inserted into the site-specific integration expression vector (pIKAA) of CMS cabbage chloroplast. Due to the fragments of TrnA and TrnI used as homologous integration fragments, the pIKAA could target to chloroplast genomes of CMS cabbage. In addition, the pIKAA vector was bicistronic. The single transcribed mRNA from the pIKAA vector contained simultaneously coding regions of KIN and aadA gene. The vector was transformed into E. coli that can grow in LB containing ampicillin and spectinomycin. The study might lay essential basis in establishment of genetic transformation system of chloroplast genome of CMS cabbage.
Two-vector representation of a nondepolarizing Mueller matrix
Gil, José J.; San José, Ignacio
2016-09-01
A geometric view of the polarimetric properties of a nondepolarizing medium is presented by means of a pair of vectors in the Poincaré sphere. An alternative representation constituted by a set of vectors contained in the equatorial plane of the Poincaré sphere is also defined and interpreted. The analyses of the magnitudes and relative orientations of the constitutive vectors of such simple representations allow for a classification of nondepolarizing media.
Concept Vector for Similarity Measurement Based on Hierarchical Domain Structure
Hong Zhe Liu; Hong Bao; Xu
2012-01-01
The concept vector model generalizes standard representations of similarity concept in terms of tree-like structure. In the model, each concept node in the hierarchical tree has ancestor and descendent concept nodes composing its relevancy nodes, thus a concept node is represented as a concept vector according to its relevancy nodes' density and the similarity of the two concepts is obtained by computing cosine similarity between their vectors. In addition, the model is adjusted in terms of l...
Support vector machines optimization based theory, algorithms, and extensions
Deng, Naiyang; Zhang, Chunhua
2013-01-01
Support Vector Machines: Optimization Based Theory, Algorithms, and Extensions presents an accessible treatment of the two main components of support vector machines (SVMs)-classification problems and regression problems. The book emphasizes the close connection between optimization theory and SVMs since optimization is one of the pillars on which SVMs are built.The authors share insight on many of their research achievements. They give a precise interpretation of statistical leaning theory for C-support vector classification. They also discuss regularized twi
Spontaneous symmetry breaking in the composite-vector-boson model
Energy Technology Data Exchange (ETDEWEB)
Garavaglia, T.
1986-11-15
Spontaneous symmetry breaking is discussed in the Abelian, QED-like, composite-vector-boson model. When the auxiliary vector field has a nonzero vacuum expectation value, a global symmetry, Lorentz invariance, is broken. It is shown that the regularization of the saddle-point conditions for the quantum fluctuation generating functional is consistent only with a spacelike vacuum expectation value for the auxiliary vector field.
Engineering BioBrick vectors from BioBrick parts
Directory of Open Access Journals (Sweden)
Knight Thomas F
2008-04-01
Full Text Available Abstract Background The underlying goal of synthetic biology is to make the process of engineering biological systems easier. Recent work has focused on defining and developing standard biological parts. The technical standard that has gained the most traction in the synthetic biology community is the BioBrick standard for physical composition of genetic parts. Parts that conform to the BioBrick assembly standard are BioBrick standard biological parts. To date, over 2,000 BioBrick parts have been contributed to, and are available from, the Registry of Standard Biological Parts. Results Here we extended the same advantages of BioBrick standard biological parts to the plasmid-based vectors that are used to provide and propagate BioBrick parts. We developed a process for engineering BioBrick vectors from BioBrick parts. We designed a new set of BioBrick parts that encode many useful vector functions. We combined the new parts to make a BioBrick base vector that facilitates BioBrick vector construction. We demonstrated the utility of the process by constructing seven new BioBrick vectors. We also successfully used the resulting vectors to assemble and propagate other BioBrick standard biological parts. Conclusion We extended the principles of part reuse and standardization to BioBrick vectors. As a result, myriad new BioBrick vectors can be readily produced from all existing and newly designed BioBrick parts. We invite the synthetic biology community to (1 use the process to make and share new BioBrick vectors; (2 expand the current collection of BioBrick vector parts; and (3 characterize and improve the available collection of BioBrick vector parts.
Isometric Reflection Vectors and Characterizations of Hilbert Spaces
Directory of Open Access Journals (Sweden)
Donghai Ji
2014-01-01
Full Text Available A known characterization of Hilbert spaces via isometric reflection vectors is based on the following implication: if the set of isometric reflection vectors in the unit sphere SX of a Banach space X has nonempty interior in SX, then X is a Hilbert space. Applying a recent result based on well-known theorem of Kronecker from number theory, we improve this by substantial reduction of the set of isometric reflection vectors needed in the hypothesis.
Recent progress in polymer-based gene delivery vectors
Institute of Scientific and Technical Information of China (English)
HUANG Shiwen; ZHUO Renxi
2003-01-01
The gene delivery system is one of the three components of a gene medicine, which is the bottle neck of current gene therapy. Nonviral vectors offer advantages over the viral system of safety, ease of manufacturing, etc. As important nonviral vectors, polymer gene delivery systems have gained increasing attention and have begun to show increasing promising. In this review, the fundamental and recent progress of polymer-based gene delivery vectors is reviewed.