WorldWideScience

Sample records for alternative route designations

  1. State alternative route designations

    International Nuclear Information System (INIS)

    1989-07-01

    Pursuant to the Hazardous Materials Transportation Act (HMTA), the Department of Transportation (DOT) has promulgated a comprehensive set of regulations regarding the highway transportation of high-level radioactive materials. These regulations, under HM-164 and HM-164A, establish interstate highways as the preferred routes for the transportation of radioactive materials within and through the states. The regulations also provide a methodology by which a state may select alternative routes. First,the state must establish a ''state routing agency,'' defined as an entity authorized to use the state legal process to impose routing requirements on carriers of radioactive material (49 CFR 171.8). Once identified, the state routing agency must select routes in accordance with Large Quantity Shipments of Radioactive Materials or an equivalent routing analysis. Adjoining states and localities should be consulted on the impact of proposed alternative routes as a prerequisite of final route selection. Lastly, the states must provide written notice of DOT of any alternative route designation before the routes are deemed effective

  2. Alternative routes for highway shipments of radioactive materials and lessons learned from state designations

    International Nuclear Information System (INIS)

    1990-07-01

    Pursuant to the Hazardous Materials Transportation Act (HMTA), the Department of Transportation (DOT) has promulgated a comprehensive set of regulations regarding the highway transportation of high-level radioactive materials. These regulations, under docket numbers HM-164 and HM-164A, establish interstate highways as the preferred routes for the transportation of radioactive materials within and through the states. The regulations also provide a methodology by which a state may select altemative routes. First, the state must establish a ''state routing agency'', defined as an entity authorized to use the state legal process to impose routing requirements on carriers of radioactive material (49 CFR 171.8). Once identified, the state routing agency must select routes in accordance with DOTs Guidelines for Selecting Preferred Highway Routes for Large Quantity Shipments of Radioactive Materials or an equivalent routing analysis. Adjoining states and localities should be consulted on the impact of proposed alternative routes as a prerequisite of final route selection. Lastly, the states must provide written notice to DOT of any alternative route designation before the routes are deemed effective. The purpose of this report is to discuss the ''lessons learned'' by the five states within the southern region that have designated alternative or preferred routes under the regulations of the Department of Transportation (DOT) established for the transportation of radioactive materials. The document was prepared by reviewing applicable federal laws and regulations, examining state reports and documents and contacting state officials and routing agencies involved in making routing decisions. In undertaking this project, the Southern States Energy Board hopes to reveal the process used by states that have designated alternative routes and thereby share their experiences (i.e., lessons learned) with other southern states that have yet to make designations

  3. Pheromone based alternative route planning

    Directory of Open Access Journals (Sweden)

    Liangbing Feng

    2016-08-01

    Full Text Available In this work, we propose an improved alternative route calculation based on alternative figures, which is suitable for practical environments. The improvement is based on the fact that the main traffic route is the road network skeleton in a city. Our approach using nodes may generate a higher possibility of overlapping. We employ a bidirectional Dijkstra algorithm to search the route. To measure the quality of an Alternative Figures (AG, three quotas are proposed. The experiment results indicate that the improved algorithm proposed in this paper is more effective than others.

  4. Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents

    Directory of Open Access Journals (Sweden)

    Rodrigo Abonia

    2018-02-01

    Full Text Available Two practical and efficient approaches have been implemented as alternative procedures for the synthesis of naftifine and novel diversely substituted analogues 16 and 20 in good to excellent yields, mediated by Mannich-type reactions as the key step of the processes. In these approaches, the γ-aminoalcohols 15 and 19 were obtained as the key intermediates and their subsequent dehydration catalyzed either by Brønsted acids like H2SO4 and HCl or Lewis acid like AlCl3, respectively, led to naftifine, along with the target allylamines 16 and 20. The antifungal assay results showed that intermediates 18 (bearing both a β-aminoketo- and N-methyl functionalities in their structures and products 20 were the most active. Particularly, structures 18b, 18c, and the allylamine 20c showed the lowest MIC values, in the 0.5–7.8 µg/mL range, against the dermatophytes Trichophyton rubrum and Trichophyton mentagrophytes. Interesting enough, compound 18b bearing a 4-Br as the substituent of the phenyl ring, also displayed high activity against Candida albicans and Cryptococcus neoformans with MIC80 = 7.8 µg/mL, being fungicide rather than fungistatic with a relevant MFC value = 15.6 µg/mL against C. neoformans.

  5. Pharmacokinetics of Alternative Administration Routes of Melatonin

    DEFF Research Database (Denmark)

    Zetner, D.; Andersen, L. P.H.; Rosenberg, J.

    2016-01-01

    Background: Melatonin is traditionally administered orally but has a poor and variable bioavailability. This study aims to present an overview of studies investigating the pharmacokinetics of alternative administration routes of melatonin. Methods: A systematic literature search was performed...... and included experimental or clinical studies, investigating pharmacokinetics of alternative administration routes of melatonin in vivo. Alternative administration routes were defined as all administration routes except oral and intravenous. Results: 10 studies were included in the review. Intranasal...... administration exhibited a quick absorption rate and high bioavailability. Transdermal administration displayed a variable absorption rate and possible deposition of melatonin in the skin. Oral transmucosal administration of melatonin exhibited a high plasma concentration compared to oral administration...

  6. Seal design alternatives study

    International Nuclear Information System (INIS)

    Van Sambeek, L.L.; Luo, D.D.; Lin, M.S.; Ostrowski, W.; Oyenuga, D.

    1993-06-01

    This report presents the results from a study of various sealing alternatives for the WIPP sealing system. Overall, the sealing system has the purpose of reducing to the extent possible the potential for fluids (either gas or liquid) from entering or leaving the repository. The sealing system is divided into three subsystems: drift and panel seals within the repository horizon, shaft seals in each of the four shafts, and borehole seals. Alternatives to the baseline configuration for the WIPP seal system design included evaluating different geometries and schedules for seal component installations and the use of different materials for seal components. Order-of-magnitude costs for the various alternatives were prepared as part of the study. Firm recommendations are not presented, but the advantages and disadvantages of the alternatives are discussed. Technical information deficiencies are identified and studies are outlined which can provide required information

  7. Alternative kynurenic acid synthesis routes studied in the rat cerebellum

    Directory of Open Access Journals (Sweden)

    Tonali eBlanco Ayala

    2015-05-01

    Full Text Available Kynurenic acid (KYNA, an astrocyte-derived, endogenous antagonist of α7 nicotinic acetylcholine and excitatory amino acid receptors, regulates glutamatergic, GABAergic, cholinergic and dopaminergic neurotransmission in several regions of the rodent brain. Synthesis of KYNA in the brain and elsewhere is generally attributed to the enzymatic conversion of L-kynurenine (L-KYN by kynurenine aminotransferases (KATs. However, alternative routes, including KYNA formation from D-kynurenine (D-KYN by D-amino acid oxidase (DAAO and the direct transformation of kynurenine to KYNA by reactive oxygen species (ROS, have been demonstrated in the rat brain. Using the rat cerebellum, a region of low KAT activity and high DAAO activity, the present experiments were designed to examine KYNA production from L-KYN or D-KYN by KAT and DAAO, respectively, and to investigate the effect of ROS on KYNA synthesis. In chemical combinatorial systems, both L-KYN and D-KYN interacted directly with peroxynitrite (ONOO- and hydroxyl radicals (OH•, resulting in the formation of KYNA. In tissue homogenates, the non-specific KAT inhibitor aminooxyacetic acid (AOAA; 1 mM reduced KYNA production from L-KYN and D-KYN by 85.1 ± 1.7% and 27.1 ± 4.5%, respectively. Addition of DAAO inhibitors (benzoic acid, kojic acid or 3-methylpyrazole-5-carboxylic acid; 5 µM each attenuated KYNA formation from L-KYN and D-KYN by ~35% and ~66%, respectively. ONOO- (25 µM potentiated KYNA production from both L-KYN and D-KYN, and these effects were reduced by DAAO inhibition. AOAA attenuated KYNA production from L-KYN + ONOO- but not from D-KYN + ONOO-. In vivo, extracellular KYNA levels increased rapidly after perfusion of ONOO- and, more prominently, after subsequent perfusion with L-KYN or D-KYN (100 µM. Taken together, these results suggest that different mechanisms are involved in KYNA production in the rat cerebellum, and that, specifically, DAAO and ROS can function as alternative routes

  8. Enhanced Design Alternative IV

    International Nuclear Information System (INIS)

    Kramer, N.E.

    1999-01-01

    This report evaluates Enhanced Design Alternative (EDA) IV as part of the second phase of the License Application Design Selection (LADS) effort. The EDA IV concept was compared to the VA reference design using criteria from the Design Input Request for LADS Phase II EDA Evaluations (CRWMS M and O 1999b) and (CRWMS M and O 1999f). Briefly, the EDA IV concept arranges the waste packages close together in an emplacement configuration known as line load. Continuous pre-closure ventilation keeps the waste packages from exceeding their 350 C cladding and 200 C (4.3.6) drift wall temperature limits. This EDA concept keeps relatively high, uniform emplacement drift temperatures (post-closure) to drive water away from the repository and thus dry out the pillars between emplacement drifts. The waste package is shielded to permit human access to emplacement drifts and includes an integral filler inside the package to reduce the amount of water that can contact the waste form. Closure of the repository is desired 50 years after first waste is emplaced. Both backfill and drip shields will be emplaced at closure to improve post-closure performance. The EDA IV concept includes more defense-in-depth layers than the VA reference design because of its backfill, drip shield, waste package shielding, and integral filler features. These features contribute to the low dose-rate to the public achieved during the first 10,000 years of repository life as shown in Figure 3. Investigation of the EDA IV concept has led to the following general conclusions: (1) The total life cycle cost for EDA IV is about $21.7 billion which equates to a $11.3 billion net present value (both figures rounded up). (2) The incidence of design basis events for EDA IV is similar to the VA reference design. (3) The emplacement of the waste packages in drifts will be similar to the VA reference design. However, heavier equipment may be required because the shielded waste package will be heavier. (4) The heavier

  9. 76 FR 73998 - Drawbridge Operation Regulations; Gulf Intracoastal Waterway (Algiers Alternate Route), Belle...

    Science.gov (United States)

    2011-11-30

    ... Operation Regulations; Gulf Intracoastal Waterway (Algiers Alternate Route), Belle Chasse, LA AGENCY: Coast... operation of the SR 23 bridge across the Gulf Intracoastal Waterway (Algiers Alternate Route), mile 3.8, at... Waterway (Algiers Alternate Route), mile 3.8, at Belle Chasse, Plaquemines Parish, Louisiana. Due to an...

  10. The MRSD web server for metabolic route search and design

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: yong cao, Deguo Xia & Haoran Zheng ### Abstract The Metabolic Route Search and Design (MRSD) server is an integrated platform for metabolic route search (MRS) and metabolic route design (MRD) based on the data from KEGG. MRS computes metabolic routes between the source metabolite and the product metabolite on the weighted compound transforming graph. Each graph represents a metabolic network. The output from a typical server run contains graphic illustrating metabolic routes ...

  11. Blockage of migration routes by dam construction: can migratory fish find alternative routes?

    Directory of Open Access Journals (Sweden)

    Rosimeire Ribeiro Antonio

    Full Text Available The present study explored the interaction between the upriver migration of fish and the blockage of their migration routes by dam construction. Specifically, we studied (i the capacity of migratory fish to locate alternative routes in the presence of an obstacle, and (ii the behavior of the fish after they were artificially transferred to the reservoir. With the use of the mark-recapture technique (tagging, the study was carried out near Porto Primavera Dam (UHE Engenheiro Sérgio Motta between 1994 and 1999, a period prior to the closure of the floodgates and the installation and operation of the fish pass facilities. The fish were caught in the dam forebay downstream, marked with LEA type tags, and released upstream (5113 individuals; 14 species and downstream (1491; 12 from the dam. The recaptures were carried out by local professional and amateur fishermen. A total of 188 individuals (2.8% were recaptured, mostly the curimba Prochilodus lineatus. Nearly half of the recaptures downstream occurred in tributaries, especially in the Paranapanema River, indicating that in the presence of an obstacle the fish are able to locate alternative migration routes. The remainder stayed in the main channel of the Paraná River, at a mean distance of less than 50 km from the release point. Of the fish released upriver from the dam, approximately half were recaptured downriver. Although the river was only partly dammed, the movement of the fish downriver suggests that they became disoriented after being transferred. Those that remained upriver avoided the reservoir and moved, rather rapidly, toward the lotic stretches farther upstream. From these results it is clear that, in the course of the decision process in installing fish passes, it is necessary to take into account the existence of spawning and nursery areas downriver and upriver from the reservoir.

  12. TWTF design alternates

    International Nuclear Information System (INIS)

    Ayers, A.L. Sr.

    1982-03-01

    The Transuranic Waste Treatment Facility (TWTF) will process transuranic (TRU) waste in retrievable storage at the Idaho National Engineering Laboratory (INEL). The costs for a TWTF concept using a slagging pyrolysis incinerator were excessive. Alternate concepts using a slow speed shredder, a rotary kiln incinerator, and concrete immobilization should result in significant cost reductions. These will be included in future TWTF considerations

  13. Alternative Fleet Architecture Design

    National Research Council Canada - National Science Library

    Johnson, Stuart E; Cebrowski, Arthur K

    2005-01-01

    .... Indeed, designing a fleet architecture composed of large numbers of manned and unmanned systems, networked together, provides coherence between building the force and operating the force against both challenges...

  14. Driver decision making in response to alternate routes.

    Science.gov (United States)

    2011-04-11

    The issue of driver route choice has been studied fairly extensively as part of the body of research on intelligent : transportation systems. A few studies cited in this literature search focus directly on Route Choice Analysis, while : many other st...

  15. Southern routes for high-level radioactive waste: Agencies, contacts, and designations

    International Nuclear Information System (INIS)

    1991-05-01

    The Southern Routes for High-Level Radioactive Waste: Agencies, Contacts and Designations is a compendium of sixteen southern states' routing programs for the transportation of high-level radioactive materials. The report identifies the state-designated routing agencies as defined under 49 Code of Federal Regulations (CFR) Part 171 and provides a reference to the source and scope of the agencies' rulemaking authority. Additionally, the state agency and contact designated by the state's governor to receive advance notification and shipment routing information under 10 CFR Parts 71 and 73 are also listed. This report also examines alternative route designations made by southern states and the lessons that were learned from the designation process

  16. Tour Route Multiobjective Optimization Design Based on the Tourist Satisfaction

    Directory of Open Access Journals (Sweden)

    Yan Han

    2014-01-01

    Full Text Available The question prompted is how to design the tour route to make the tourists get the maximum satisfactions considering the tourists’ demand. The influence factors of the tour route choices of tourists were analyzed and tourists’ behavior characteristics and psychological preferences were regarded as the important influence factors based on the tourist behavioral theories. A questionnaire of tourists’ tour route information and satisfaction degree was carried out. Some information about the scene spot and tourists demand and tour behaviors characteristic such as visit frequency, number of attractions visited was obtained and analyzed. Based on the convey datum, tour routes multiobjective optimization functions were prompted for the tour route design regarding the maximum satisfaction and the minimum tour distance as the optimal objective. The available routes are listed and categorized. Based on the particle swarm optimization model, the priorities of the tour route are calculated and finally the suggestion depth tour route and quick route tour routes are given considering the different tour demands of tourists. The results can offer constructive suggestions on how to design tour routes on the part of tourism enterprises and how to choose a proper tour route on the part of tourists.

  17. Model-Checking Driven Design of QoS-Based Routing Protocol for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Zhi Chen

    2015-01-01

    Full Text Available Accurate and reliable routing protocols with Quality of Service (QoS support determine the mission-critical application efficiency in WSNs. This paper proposes a model-checking design driven framework for designing the QoS-based routing protocols of WSNs, which involves the light-weight design process, the timed automata model, and the alternative QoS verification properties. The accurate feedback of continually model checking in the iterative design process effectively stimulates the parameter tuning of the protocols. We demonstrate the straightforward and modular characteristics of the proposed framework in designing a prototype QoS-based routing protocol. The prototype study shows that the model-checking design framework may complement other design methods and ensure the QoS implementation of the QoS-based routing protocol design for WSNs.

  18. Novel Congestion-Free Alternate Routing Path Scheme using Stackelberg Game Theory Model in Wireless Networks

    Directory of Open Access Journals (Sweden)

    P. Chitra

    2017-04-01

    Full Text Available Recently, wireless network technologies were designed for most of the applications. Congestion raised in the wireless network degrades the performance and reduces the throughput. Congestion-free network is quit essen- tial in the transport layer to prevent performance degradation in a wireless network. Game theory is a branch of applied mathematics and applied sciences that used in wireless network, political science, biology, computer science, philosophy and economics. e great challenges of wireless network are their congestion by various factors. E ective congestion-free alternate path routing is pretty essential to increase network performance. Stackelberg game theory model is currently employed as an e ective tool to design and formulate conges- tion issues in wireless networks. is work uses a Stackelberg game to design alternate path model to avoid congestion. In this game, leaders and followers are selected to select an alternate routing path. e correlated equilibrium is used in Stackelberg game for making better decision between non-cooperation and cooperation. Congestion was continuously monitored to increase the throughput in the network. Simulation results show that the proposed scheme could extensively improve the network performance by reducing congestion with the help of Stackelberg game and thereby enhance throughput.

  19. 76 FR 75505 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway (Algiers Alternate Route), Belle...

    Science.gov (United States)

    2011-12-02

    ... Operation Regulation; Gulf Intracoastal Waterway (Algiers Alternate Route), Belle Chasse, LA AGENCY: Coast... regulation governing the operation of the SR 23 bridge across the Gulf Intracoastal Waterway (Algiers... the SR 23 vertical lift bridge across the Gulf Intracoastal Waterway (Algiers Alternate Route), mile 3...

  20. Alternative Design of Boat Fenders

    DEFF Research Database (Denmark)

    Banke, Lars

    1996-01-01

    On offshore platforms the purpose of fenders is to protect the oil-risers against minor accidental collisions with supply vessels. Normally, the fender is designed by use of thin-walled tubes. However, the tube itself is not capable of resisting the impact load of the boat. Therefore, alternative...

  1. Routing of individual polymers in designed patterns

    DEFF Research Database (Denmark)

    Knudsen, Jakob Bach; Liu, Lei; Kodal, Anne Louise Bank

    2015-01-01

    Synthetic polymers are ubiquitous in the modern world, but our ability to exert control over the molecular conformation of individual polymers is very limited. In particular, although the programmable self-assembly of oligonucleotides and proteins into artificial nanostructures has been...... demonstrated, we currently lack the tools to handle other types of synthetic polymers individually and thus the ability to utilize and study their single-molecule properties. Here we show that synthetic polymer wires containing short oligonucleotides that extend from each repeat can be made to assemble...... into arbitrary routings. The wires, which can be more than 200 nm in length, are soft and bendable, and the DNA strands allow individual polymers to self-assemble into predesigned routings on both two- and three-dimensional DNA origami templates. The polymers are conjugated and potentially conducting, and could...

  2. Many Roads to Travel: Alternative Approaches to Route Selection for Yucca Mountain Shipments

    International Nuclear Information System (INIS)

    Dilger, F.; Halstead, R. J.

    2003-01-01

    This paper examines the routing implications of the potential shipment of spent nuclear fuel and high-level radioactive waste to the proposed repository at Yucca Mountain, Nevada. The authors describe a model which can be used to evaluate the impacts of transporting spent nuclear fuel nationally and in the State of Nevada. The authors used this model to evaluate the cross-country highway routes identified in the DOE's Final Environmental Impact Statement and three alternative routing scenarios. The authors evaluate these routing scenarios based on four attributes: counties, exposed populations, total county populations, and shipment miles. The authors further evaluate the impacts of these alternative routing scenarios on two selected corridor states. The authors conclude that routing decisions have significantly different impacts on different state and local governments

  3. Adolescent school travel: Is online mapping a practical alternative to GPS-assessed travel routes?

    DEFF Research Database (Denmark)

    Stewart, Tom; Schipperijn, Jasper; Snizek, Bernhard

    2017-01-01

    noticeable burden on participants and processing these data is time consuming and error-prone. Interactive online mapping surveys allow users to draw their own travel routes, and may offer a time and cost-effective alternative; however, these routes are still self-reported, and their true accuracy remains...

  4. Taking an Alternative Route: A guide for fleet operators and individual owners using alternative fuels in cars and trucks

    Energy Technology Data Exchange (ETDEWEB)

    LaRocque, T.

    2001-04-18

    Taking an Alternative Route is a 30-page guide for fleet managers and individual owners on using alternative fuels in cars and trucks. Discussed in detail are all fuels authorized for federal credits under the Energy Policy Act of 1992 (EPAct). The publication informs federal and state fleet managers about how to comply with EPAct, and provides information about the Clean Air Act Amendments.

  5. Taking an Alternative Route: A guide for fleet operators and individual owners using alternative fuels in cars and trucks

    International Nuclear Information System (INIS)

    LaRocque, T.

    2001-01-01

    Taking an Alternative Route is a 30-page guide for fleet managers and individual owners on using alternative fuels in cars and trucks. Discussed in detail are all fuels authorized for federal credits under the Energy Policy Act of 1992 (EPAct). The publication informs federal and state fleet managers about how to comply with EPAct, and provides information about the Clean Air Act Amendments

  6. Parallel algorithms for placement and routing in VLSI design. Ph.D. Thesis

    Science.gov (United States)

    Brouwer, Randall Jay

    1991-01-01

    The computational requirements for high quality synthesis, analysis, and verification of very large scale integration (VLSI) designs have rapidly increased with the fast growing complexity of these designs. Research in the past has focused on the development of heuristic algorithms, special purpose hardware accelerators, or parallel algorithms for the numerous design tasks to decrease the time required for solution. Two new parallel algorithms are proposed for two VLSI synthesis tasks, standard cell placement and global routing. The first algorithm, a parallel algorithm for global routing, uses hierarchical techniques to decompose the routing problem into independent routing subproblems that are solved in parallel. Results are then presented which compare the routing quality to the results of other published global routers and which evaluate the speedups attained. The second algorithm, a parallel algorithm for cell placement and global routing, hierarchically integrates a quadrisection placement algorithm, a bisection placement algorithm, and the previous global routing algorithm. Unique partitioning techniques are used to decompose the various stages of the algorithm into independent tasks which can be evaluated in parallel. Finally, results are presented which evaluate the various algorithm alternatives and compare the algorithm performance to other placement programs. Measurements are presented on the parallel speedups available.

  7. Exposure to Black Carbon during Bicycle Commuting–Alternative Route Selection

    Directory of Open Access Journals (Sweden)

    Borut Jereb

    2018-01-01

    Full Text Available Traffic air pollution significantly influences cyclists using cycling routes near main roads. We analyze the dependency of black carbon (BC concentrations in relation to the proximity to their traffic sources. We performed static and mobile measurements of BC using aethalometers at chosen sites and cycling routes in Celje, Slovenia—static measurements at two road-side sites and an urban background site. Mobile measurements were performed simultaneously at an existing cycling route and an alternative route away from the busy roads. BC concentration apportioned to traffic decreases with the distance from the sources on the main road. The exposure of cyclists to BC can be greatly reduced by moving the cycling route away from busy roads, hence we propose an alternative route and show that traffic planning and management should include all modes of transport. Results imply that street intersections along the cycling routes influence the cyclists’ exposure and should be as few as possible when planning cycling routes in urban areas.

  8. ROUTE PLAN DESIGNER FOR TRACTOR GUIDANCE SYSTEMS

    DEFF Research Database (Denmark)

    Sveistrup, Daniel; Jørgensen, Rasmus Nyholm; Green, Ole

    2010-01-01

    in their file formats and operationalrequirements, thereby creating an unnecessary burden for the field trial managers and researchersoperating on different computational platforms such as Windows, Mac or Linux.This paper demonstrates a methodological proof of concept for a software solution for assisting...... the benefits of the software. 1- a modified fullscalerandomized split-plot design of 840 parcels and 15 treatment combinations. 2 - a maize fieldsetup ensuring a prototype crop-weed detection camera to experience as many crops, weed and soilcolor conditions as possible. For both cases, after the overall layout...

  9. Forks in the Road. Alternative Routes for International Climate Policies and their Implications for the Netherlands

    International Nuclear Information System (INIS)

    Slingerland, S.; Meyer, L.; Van Vuuren, D.; Den Elzen, M.

    2011-11-01

    Several scenarios are possible for future international climate policies, each with a different role in the climate negotiations under the United Nations Framework Convention on Climate Change (UNFCCC). These scenarios assume policies that are comparable to the current policies, as well as more fragmented and more integrated international climate policies. The various alternative routes have been assessed with respect to their potential consequences. These assessments showed that none of the proposed routes could fully replace the current negotiation process under the UNFCCC, but rather that they could contribute to generating societal support for future climate policies. In addition, the report presents an analysis of how the Netherlands could use this development of alternative routes for international climate policy. Possible responses by the Netherlands to each of these scenarios would depend on the degree to which climate change as a policy topic is considered a priority in the Netherlands.

  10. 76 FR 76640 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway (Algiers Alternate Route), Belle...

    Science.gov (United States)

    2011-12-08

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2011-0959] Drawbridge Operation Regulation; Gulf Intracoastal Waterway (Algiers Alternate Route), Belle Chasse, LA ACTION: Notice..., the Coast Guard placed the Notice of Proposed Rulemaking, Gulf Intracoastal Waterway (Algiers...

  11. Evaluation of Clark County School District's Alternative Route to Licensure Program from the Program Participants' Perspectives

    Science.gov (United States)

    Kenyon, James J., Jr.

    2013-01-01

    This evaluation assesses the Alternative Route to Licensure (ARL) program of the Clark County School District (CCSD), in Clark County, Nevada from the program participants' perspectives. The program was implemented to reduce teacher shortages in the school district and allow persons with non-education-related Bachelor's Degrees to obtain teaching…

  12. On Intelligent Design and Planning Method of Process Route Based on Gun Breech Machining Process

    Science.gov (United States)

    Hongzhi, Zhao; Jian, Zhang

    2018-03-01

    The paper states an approach of intelligent design and planning of process route based on gun breech machining process, against several problems, such as complex machining process of gun breech, tedious route design and long period of its traditional unmanageable process route. Based on gun breech machining process, intelligent design and planning system of process route are developed by virtue of DEST and VC++. The system includes two functional modules--process route intelligent design and its planning. The process route intelligent design module, through the analysis of gun breech machining process, summarizes breech process knowledge so as to complete the design of knowledge base and inference engine. And then gun breech process route intelligently output. On the basis of intelligent route design module, the final process route is made, edited and managed in the process route planning module.

  13. Environmental evaluation of route alternative system - technological approach of environmental viability project study; Sistema de avaliacao ambiental de alternativas de percursos - uma abordagem tecnologica para estudos de viabilidade ambiental de projetos

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Wilson Jose de; Porciano, Patricia Pereira [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil); Alvarez, Beatriz Silva Villa; Casanova, Marco Antonio; Carvalho, Marcelo Tilio Monteiro de; Montenegro, Anselmo Antunes; Carvalho, Paulo Cezar Pinto [Pontificia Univ. Catolica do Rio de Janeiro, RJ (Brazil). Dept. de Informatica. Grupo de Tecnologia em Computacao Grafica (TECGRAF)

    2003-07-01

    SAAAP - Routing Alternatives Environmental Evaluation System - was designed to select the best alternative pipeline route. The system takes into account economic, environmental and engineering factors, according to an optimality criterion that combines several variables, such as vegetation coverage, soil type and declivity. The system is operational and has been tested in several realistic projects. (author)

  14. DESIGN OF ALTERNATIVE ENERGY SOURCES

    Directory of Open Access Journals (Sweden)

    Popa Stefania

    2013-11-01

    Full Text Available By energy sources we understand technologies and materials used to obtain various forms of energy necessary for the development of society. These sources must be in adequate quantities and be conveniently exploited in terms of technical, economic and sustainable perspective. Alternative energy uses the inherent power of natural sources like wind, tides, the sun. Alternative energy is a term used for some energy sources and energy storage technologies. Generally it indicates energies that are nontraditional and have low impact to the environment. The alternative energy term is used in contrast with the term fossil fuel according to some sources, while other sources use it with the meaning of renewable energy purposes.

  15. Life Cycle Design - a Route to the Sustainable Industrial Culture?

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky; Wenzel, Henrik; Alting, Leo

    1999-01-01

    In the attempt to reorient Society's development in a more sustainable direction attention is focused on the environmental impact of products and systems over their entire life cycle, but how can the environmental life cycle perspective be introduced into the design of new solutions and how much...... can be optained through life cycle design? The authors' experience with integration of environmental considerations in product development is presented, ranging from the detailed interactive approach to the EDIP-method through various simplified approaches. The potential for environmental improvements...... is reviewed and the overall question of to what extent life cycle design is a route to the sustainable industrial culture is discussed....

  16. ALTERNATIVE ROUTES OF DRUG ADMINISTRATION: ADVANTAGES AND DISADVANTAGES (SUBJECT REVIEW OF AMERICAN ACADEMY OF PEDIATRICS

    Directory of Open Access Journals (Sweden)

    article editorial

    2006-01-01

    Full Text Available During the past 20 years advances in drug formulations and innovative routes of administration have been made. Our understanding of drug transport across tissues has increased. These changes have often resulted in improved patient adherence to the therapeutic regiment and pharmacologic response. The administration of drugs by transdermal or transmucosal routes offers the advantage of being relatively painless. Also, the potential for greater flexibility in a variety of clinical situations exists, often precluding the need to establish intravinus access which is a particular benefit for children. This statement focuses on the advantages and disadvantages of alternative routes of drug administration. Issues of particular importance in the care of pediatric patients especially factors that could lead to drug-relaxed toxicity or adverse responses are emphasized.Key words: drug formulation, pharmacoKINETICS, pharmacodynamics, drug, children.

  17. Meeting Air Transportation Demand in 2025 by Using Larger Aircraft and Alternative Routing to Complement NextGen Operational Improvements

    Science.gov (United States)

    Smith, Jeremy C.; Guerreiro, Nelson M.; Viken, Jeffrey K.; Dollyhigh, Samuel M.; Fenbert, James W.

    2010-01-01

    A study was performed that investigates the use of larger aircraft and alternative routing to complement the capacity benefits expected from the Next Generation Air Transportation System (NextGen) in 2025. National Airspace System (NAS) delays for the 2025 demand projected by the Transportation Systems Analysis Models (TSAM) were assessed using NASA s Airspace Concept Evaluation System (ACES). The shift in demand from commercial airline to automobile and from one airline route to another was investigated by adding the route delays determined from the ACES simulation to the travel times used in the TSAM and re-generating new flight scenarios. The ACES simulation results from this study determined that NextGen Operational Improvements alone do not provide sufficient airport capacity to meet the projected demand for passenger air travel in 2025 without significant system delays. Using larger aircraft with more seats on high-demand routes and introducing new direct routes, where demand warrants, significantly reduces delays, complementing NextGen improvements. Another significant finding of this study is that the adaptive behavior of passengers to avoid congested airline-routes is an important factor when projecting demand for transportation systems. Passengers will choose an alternative mode of transportation or alternative airline routes to avoid congested routes, thereby reducing delays to acceptable levels for the 2025 scenario; the penalty being that alternative routes and the option to drive increases overall trip time by 0.4% and may be less convenient than the first-choice route.

  18. Stochastic Petri nets for the reliability analysis of communication network applications with alternate-routing

    International Nuclear Information System (INIS)

    Balakrishnan, Meera; Trivedi, Kishor S.

    1996-01-01

    In this paper, we present a comparative reliability analysis of an application on a corporate B-ISDN network under various alternate-routing protocols. For simple cases, the reliability problem can be cast into fault-tree models and solved rapidly by means of known methods. For more complex scenarios, state space (Markov) models are required. However, generation of large state space models can get very labor intensive and error prone. We advocate the use of stochastic reward nets (a variant of stochastic Petri nets) for the concise specification, automated generation and solution of alternate-routing protocols in networks. This paper is written in a tutorial style so as to make it accessible to a large audience

  19. British Columbia : an alternative design

    International Nuclear Information System (INIS)

    Ostergaard, P.

    2003-01-01

    This PowerPoint presentation outlined the British Columbia Ministry of Energy and Mines' approach to the electricity market. A brief overview of the electric system in the province was provided, examining capacity (primarily hydro based) and the utility sector with its public ownership. In British Columbia, 80 per cent of the electricity is generated by British Columbia Hydro (BC Hydro). The rates are based on cost of service. British Columbia's market is western North America. A comparison of monthly bills for several large cities, both Canadian and American, was displayed. The market reviews conducted in 1995, 1998, and 2002 were reviewed and the major recommendations discussed. The author identified the opportunities in the province, discussing natural gas and coal for electricity production, resource potential, demand, and private sector capacity. The challenges facing the province are: cost effective development of resources to meet energy demand; aging infrastructure, high reliability requirements and economic growth; evolving electricity market structure in the United States; and, monopoly. The transmission system was reviewed with reference to trade with the Pacific Northwest, flexibility and storage. The energy plan objectives for the future were presented, including low rates and public ownership, secure and reliable supply, more private sector opportunities, and environmental responsibility. The alternative market structure includes regulated market characteristics, access to trade, and customer focus. figs

  20. Alternate Routes of Administration among Prescription Opioid Misusers and Associations with Sexual HIV Transmission Risk Behaviors.

    Science.gov (United States)

    Buttram, Mance E; Kurtz, Steven P

    2016-01-01

    Literature suggests that young adult prescription opioid misusers who are using alternate routes of administration (e.g., snorting, injecting) may be engaging in sexual and non-sexual HIV risk behaviors. This study examines demographics, substance use, sexual risk behavior, and health and social problems associated with alternate routes of administration of prescription opioids among a sample of young adult prescription opioid misusers. Data are drawn from baseline assessments from a behavioral intervention trial. Eligible participants were ages 18-39, and reported recent (past 90 days) heterosexual sex, and recent and regular substance use and attendance at large, recognized local nightclubs. The analyses include 446 racially/ethnically diverse participants. In bivariate regression models, compared to those who did not, participants reporting alternate routes of administration (n = 209) were more likely to be White (p sexual victimization history (p = 0.003), and severe mental distress (p sexual HIV transmission risk behaviors. Early prevention and intervention efforts that address sexual and non-sexual HIV risk behaviors are warranted.

  1. A generic methodology for processing route synthesis and design based on superstructure optimization

    DEFF Research Database (Denmark)

    Bertran, Maria-Ona; Frauzem, Rebecca; Sanchez-Arcilla, Ana Sofia

    2017-01-01

    In this paper, a systematic framework for novel and sustainable synthesis-design of processing routes is presented along with the associated computer-aided methods and tools. In Stage 1, superstructure optimization is used to determine the optimal processing route(s). In Stage 2, the design issue...

  2. Victim derogation and victim enhancement as alternate routes to system justification.

    Science.gov (United States)

    Kay, Aaron C; Jost, John T; Young, Sean

    2005-03-01

    Abstract-Numerous studies have documented the potential for victim-blaming attributions to justify the status quo. Recent work suggests that complementary, victim-enhancing stereotypes may also increase support for existing social arrangements. We seek to reconcile these seemingly contradictory findings by proposing that victim derogation and victim enhancement are alternate routes to system justification, with the preferred route depending on the perception of a causal link between trait and outcome. Derogating "losers" (and lionizing "winners") on traits (e.g., intelligence) that are causally related to outcomes (e.g., wealth vs. poverty) serves to increase system justification, as does compensating "losers" (and downgrading "winners") on traits (e.g., physical attractiveness) that are causally unrelated to those outcomes. We provide converging evidence using system-threat and stereotype-activation paradigms.

  3. Alternative chemical-based synthesis routes and characterization of nano-scale particles

    Energy Technology Data Exchange (ETDEWEB)

    Brocchi, E.A. [Department of Material Science and Metallurgy, Catholic University of Rio de Janeiro, DCMM-PUC-RIO, R. Margues de S. Vicente 225, C.P 3890-Gavea, 22451-970 Rio de Janeiro (Brazil); Motta, M.S. [Department of Material Science and Metallurgy, Catholic University of Rio de Janeiro, DCMM-PUC-RIO, R. Margues de S. Vicente 225, C.P 3890-Gavea, 22451-970 Rio de Janeiro (Brazil); Solorzano, I.G. [Department of Material Science and Metallurgy, Catholic University of Rio de Janeiro, DCMM-PUC-RIO, R. Margues de S. Vicente 225, C.P 3890-Gavea, 22451-970 Rio de Janeiro (Brazil)]. E-mail: guilsol@dcmm.puc-rio.br; Jena, P.K. [Department of Material Science and Metallurgy, Catholic University of Rio de Janeiro, DCMM-PUC-RIO, R. Margues de S. Vicente 225, C.P 3890-Gavea, 22451-970 Rio de Janeiro (Brazil); Moura, F.J. [Department of Material Science and Metallurgy, Catholic University of Rio de Janeiro, DCMM-PUC-RIO, R. Margues de S. Vicente 225, C.P 3890-Gavea, 22451-970 Rio de Janeiro (Brazil)

    2004-09-25

    Different nano-scale particles have been synthesized by alternative routes: nitrates dehydratation and oxide, or co-formed oxides, reduction by hydrogen. Chemical-based synthesis routes are described and thermodynamics studies and kinetics data are presented to support the feasibility for obtaining single-phase oxides and co-formed two-phase oxides. In addition, the reduction reaction has been applied to successfully produce metal/ceramic nanocomposites. Structural characterization has been carried out by means of X-ray diffraction and, more extensively, transmission electron microscopy operating in conventional diffraction contrast mode (CTEM) and high-resolution mode (HRTEM). Nano-scale size distribution of oxide particles is well demonstrated together with their defect-free structure in the lower range, around 20 nm, size. Structural features related to the synthesized nano-composites are also presented.

  4. Alternative chemical-based synthesis routes and characterization of nano-scale particles

    International Nuclear Information System (INIS)

    Brocchi, E.A.; Motta, M.S.; Solorzano, I.G.; Jena, P.K.; Moura, F.J.

    2004-01-01

    Different nano-scale particles have been synthesized by alternative routes: nitrates dehydratation and oxide, or co-formed oxides, reduction by hydrogen. Chemical-based synthesis routes are described and thermodynamics studies and kinetics data are presented to support the feasibility for obtaining single-phase oxides and co-formed two-phase oxides. In addition, the reduction reaction has been applied to successfully produce metal/ceramic nanocomposites. Structural characterization has been carried out by means of X-ray diffraction and, more extensively, transmission electron microscopy operating in conventional diffraction contrast mode (CTEM) and high-resolution mode (HRTEM). Nano-scale size distribution of oxide particles is well demonstrated together with their defect-free structure in the lower range, around 20 nm, size. Structural features related to the synthesized nano-composites are also presented

  5. Molecular basis of the evolution of alternative tyrosine biosynthetic routes in plants

    Energy Technology Data Exchange (ETDEWEB)

    Schenck, Craig A.; Holland, Cynthia K.; Schneider, Matthew R.; Men, Yusen; Lee, Soon Goo; Jez, Joseph M.; Maeda , Hiroshi A. (UW); (WU)

    2017-06-26

    L-Tyrosine (Tyr) is essential for protein synthesis and is a precursor of numerous specialized metabolites crucial for plant and human health. Tyr can be synthesized via two alternative routes by different key regulatory TyrA family enzymes, prephenate dehydrogenase (PDH, also known as TyrAp) or arogenate dehydrogenase (ADH, also known as TyrAa), representing a unique divergence of primary metabolic pathways. The molecular foundation underlying the evolution of these alternative Tyr pathways is currently unknown. Here we characterized recently diverged plant PDH and ADH enzymes, obtained the X-ray crystal structure of soybean PDH, and identified a single amino acid residue that defines TyrA substrate specificity and regulation. Structures of mutated PDHs co-crystallized with Tyr indicate that substitutions of Asn222 confer ADH activity and Tyr sensitivity. Reciprocal mutagenesis of the corresponding residue in divergent plant ADHs further introduced PDH activity and relaxed Tyr sensitivity, highlighting the critical role of this residue in TyrA substrate specificity that underlies the evolution of alternative Tyr biosynthetic pathways in plants.

  6. Molecular basis of the evolution of alternative tyrosine biosynthetic routes in plants.

    Science.gov (United States)

    Schenck, Craig A; Holland, Cynthia K; Schneider, Matthew R; Men, Yusen; Lee, Soon Goo; Jez, Joseph M; Maeda, Hiroshi A

    2017-09-01

    L-Tyrosine (Tyr) is essential for protein synthesis and is a precursor of numerous specialized metabolites crucial for plant and human health. Tyr can be synthesized via two alternative routes by different key regulatory TyrA family enzymes, prephenate dehydrogenase (PDH, also known as TyrA p ) or arogenate dehydrogenase (ADH, also known as TyrA a ), representing a unique divergence of primary metabolic pathways. The molecular foundation underlying the evolution of these alternative Tyr pathways is currently unknown. Here we characterized recently diverged plant PDH and ADH enzymes, obtained the X-ray crystal structure of soybean PDH, and identified a single amino acid residue that defines TyrA substrate specificity and regulation. Structures of mutated PDHs co-crystallized with Tyr indicate that substitutions of Asn222 confer ADH activity and Tyr sensitivity. Reciprocal mutagenesis of the corresponding residue in divergent plant ADHs further introduced PDH activity and relaxed Tyr sensitivity, highlighting the critical role of this residue in TyrA substrate specificity that underlies the evolution of alternative Tyr biosynthetic pathways in plants.

  7. Spectrum efficient distance-adaptive paths for fixed and fixed-alternate routing in elastic optical networks

    Science.gov (United States)

    Agrawal, Anuj; Bhatia, Vimal; Prakash, Shashi

    2018-01-01

    Efficient utilization of spectrum is a key concern in the soon to be deployed elastic optical networks (EONs). To perform routing in EONs, various fixed routing (FR), and fixed-alternate routing (FAR) schemes are ubiquitously used. FR, and FAR schemes calculate a fixed route, and a prioritized list of a number of alternate routes, respectively, between different pairs of origin o and target t nodes in the network. The route calculation performed using FR and FAR schemes is predominantly based on either the physical distance, known as k -shortest paths (KSP), or on the hop count (HC). For survivable optical networks, FAR usually calculates link-disjoint (LD) paths. These conventional routing schemes have been efficiently used for decades in communication networks. However, in this paper, it has been demonstrated that these commonly used routing schemes cannot utilize the network spectral resources optimally in the newly introduced EONs. Thus, we propose a new routing scheme for EON, namely, k -distance adaptive paths (KDAP) that efficiently utilizes the benefit of distance-adaptive modulation, and bit rate-adaptive superchannel capability inherited by EON to improve spectrum utilization. In the proposed KDAP, routes are found and prioritized on the basis of bit rate, distance, spectrum granularity, and the number of links used for a particular route. To evaluate the performance of KSP, HC, LD, and the proposed KDAP, simulations have been performed for three different sized networks, namely, 7-node test network (TEST7), NSFNET, and 24-node US backbone network (UBN24). We comprehensively assess the performance of various conventional, and the proposed routing schemes by solving both the RSA and the dual RSA problems under homogeneous and heterogeneous traffic requirements. Simulation results demonstrate that there is a variation amongst the performance of KSP, HC, and LD, depending on the o - t pair, and the network topology and its connectivity. However, the proposed

  8. 36 CFR 4.10 - Travel on park roads and designated routes.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Travel on park roads and designated routes. 4.10 Section 4.10 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR VEHICLES AND TRAFFIC SAFETY § 4.10 Travel on park roads and designated routes. (a...

  9. Reservoir Routing on Double-Peak Design Flood

    Directory of Open Access Journals (Sweden)

    Andrea Gioia

    2016-11-01

    Full Text Available This work investigates the routing effect provided by an artificial reservoir to a double-peak flood of a given return period. The present paper introduces a dimensionless form of the reservoir balance equation that describes the hydrologic-hydraulic processes that may occur and allows for the evaluation of the reservoir routing coefficient (RC. Exploiting this equation, an extensive sensitivity analysis based on the use of two simple parametric indices that depend on the storage capacity (SC of the reservoir, the discharge capacity (DC of the spillway (with fixed-crest and the hydrologic behavior of the basin was performed.

  10. Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway

    Science.gov (United States)

    de Vries, Erik; Tscherne, Donna M.; Wienholts, Marleen J.; Cobos-Jiménez, Viviana; Scholte, Florine; García-Sastre, Adolfo; Rottier, Peter J. M.; de Haan, Cornelis A. M.

    2011-01-01

    Influenza A virus (IAV) enters host cells upon binding of its hemagglutinin glycoprotein to sialylated host cell receptors. Whereas dynamin-dependent, clathrin-mediated endocytosis (CME) is generally considered as the IAV infection pathway, some observations suggest the occurrence of an as yet uncharacterized alternative entry route. By manipulating entry parameters we established experimental conditions that allow the separate analysis of dynamin-dependent and -independent entry of IAV. Whereas entry of IAV in phosphate-buffered saline could be completely inhibited by dynasore, a specific inhibitor of dynamin, a dynasore-insensitive entry pathway became functional in the presence of fetal calf serum. This finding was confirmed with the use of small interfering RNAs targeting dynamin-2. In the presence of serum, both IAV entry pathways were operational. Under these conditions entry could be fully blocked by combined treatment with dynasore and the amiloride derivative EIPA, the hallmark inhibitor of macropinocytosis, whereas either drug alone had no effect. The sensitivity of the dynamin-independent entry pathway to inhibitors or dominant-negative mutants affecting actomyosin dynamics as well as to a number of specific inhibitors of growth factor receptor tyrosine kinases and downstream effectors thereof all point to the involvement of macropinocytosis in IAV entry. Consistently, IAV particles and soluble FITC-dextran were shown to co-localize in cells in the same vesicles. Thus, in addition to the classical dynamin-dependent, clathrin-mediated endocytosis pathway, IAV enters host cells by a dynamin-independent route that has all the characteristics of macropinocytosis. PMID:21483486

  11. Minimizing the Carbon Footprint for the Time-Dependent Heterogeneous-Fleet Vehicle Routing Problem with Alternative Paths

    Directory of Open Access Journals (Sweden)

    Wan-Yu Liu

    2014-07-01

    Full Text Available Torespondto the reduction of greenhouse gas emissions and global warming, this paper investigates the minimal-carbon-footprint time-dependent heterogeneous-fleet vehicle routing problem with alternative paths (MTHVRPP. This finds a route with the smallestcarbon footprint, instead of the shortestroute distance, which is the conventional approach, to serve a number of customers with a heterogeneous fleet of vehicles in cases wherethere may not be only one path between each pair of customers, and the vehicle speed differs at different times of the day. Inheriting from the NP-hardness of the vehicle routing problem, the MTHVRPP is also NP-hard. This paper further proposes a genetic algorithm (GA to solve this problem. The solution representedbyour GA determines the customer serving ordering of each vehicle type. Then, the capacity check is used to classify multiple routes of each vehicle type, and the path selection determines the detailed paths of each route. Additionally, this paper improves the energy consumption model used for calculating the carbon footprint amount more precisely. Compared with the results without alternative paths, our experimental results show that the alternative path in this experimenthas a significant impact on the experimental results in terms of carbon footprint.

  12. Refuge alternatives relief valve testing and design.

    Science.gov (United States)

    Lutz, T J; Bissert, P T; Homce, G T; Yonkey, J A

    2016-10-01

    The U.S. National Institute for Occupational Safety and Health (NIOSH) has been researching refuge alternatives (RAs) since 2007. RAs typically have built-in pressure relief valves (PRVs) to prevent the unit from reaching unsafe pressures. The U.S. Mine Safety and Health Administration requires that these valves vent the chamber at a maximum pressure of 1.25 kPa (0.18 psi, 5.0 in. H 2 O), or as specified by the manufacturer, above mine atmospheric pressure in the RA. To facilitate PRV testing, an instrumented benchtop test fixture was developed using an off-the-shelf centrifugal blower and ductwork. Relief pressures and flow characteristics were measured for three units: (1) a modified polyvinyl chloride check valve, (2) an off-the-shelf brass/cast-iron butterfly check valve and (3) a commercially available valve that was designed specifically for one manufacturer's steel prefabricated RAs and had been adapted for use in one mine operator's built-in-place RA. PRVs used in tent-style RAs were not investigated. The units were tested with different modifications and configurations in order to check compliance with Title 30 Code of Federal Regulations, or 30 CFR, regulations. The commercially available relief valve did not meet the 30 CFR relief pressure specification but may meet the manufacturer's specification. Alternative valve designs were modified to meet the 30 CFR relief pressure specification, but all valve designs will need further design research to examine survivability in the event of a 103 kPa (15.0 psi) impulse overpressure during a disaster.

  13. Alternative Routes to Teacher Professional Identity: Exploring the Conflated Sub-Identities of Teach for America Corps Members

    Science.gov (United States)

    Thomas, Matthew A. M.; Mockler, Nicole

    2018-01-01

    Research on the development of professional identity for teachers who enter the profession through alternative routes is still in its infancy. In contrast to their peers who complete traditional initial teacher education programs, these teachers are exposed to different conditions and constraints that produce a range of sub-identities previously…

  14. Glass reactive sintering as an alternative route for the synthesis of NZP glass-ceramics

    International Nuclear Information System (INIS)

    Chenu, Sebastien; Lebullenger, Ronan; Benard-Rocherulle, Patricia; Calvez, Guillaume; Guillou, Olivier; Rocherulle, Jean; Kidari, Abdessamad; Pomeroy, Mickael J.; Hampshire, Stuart

    2012-01-01

    The NZP-type crystal structure allows a large number of ionic substitutions which leads to ceramics with adjustable thermal expansion properties or interesting ionic conductivity. However, NZP is difficult to fabricate into monoliths because it requires both high temperatures and long sintering times. An alternative low temperature route to obtain a tungsten (IV) and tin (IV) containing NZP crystalline phase uses a process of glass reactive sintering of a phosphate glass. Using a microwave oven, a glass with the appropriate composition in the NaPO 3 -Sn(II)O-W(VI)O 3 ternary diagram is prepared by a conventional melting and casting technique. After crushing, the glass powder is pressed at room temperature. The green pellet is cured during various times at temperatures where glass reactive sintering takes place. From XRD and DTA experiments, we have shown that different parameters influence the achievement of NZP phase. Consequently, specific conditions, such as (i) initial glass composition, (ii) equimolar quantities of SnO and WO 3 , (iii) glass particle size lower than 100 μ m, and (iv) curing conducted under air, are required to obtain a glass-ceramic with a single crystalline phase with the NZP-type crystal structure. (authors)

  15. Study of alternative routes for the production of innovative radionuclides for medical applications

    International Nuclear Information System (INIS)

    Duchemin, Charlotte

    2015-01-01

    Nuclear medicine is a specialty that uses radioactive nuclei for therapy or diagnosis of diseases such as different types of cancer. These radionuclides are coupled to carrier molecules to target sick cells. Currently, only few isotopes are used in clinical practice. However, many others may be of medical interest due to their emitted radiation and/or their half-life that can be adapted to the carrier molecule transit time and to the pathology. The aim of this PhD thesis is to study the production of innovative radionuclides for therapy and diagnosis applications in collaboration with the GIP ARRONAX, which possesses a multi-particle high energy cyclotron. A fundamental physical parameter to access the production rate of a radionuclide is the production cross section. Experimental data were measured for a selection of radionuclides: photon emitter (Tc-99m) and positron emitter (Sc-44g) for diagnosis, as well as electron emitters (Re-186, Tb-155 and Sn-117m) and α particles emitters (Th-226, Ra-223 and Bi-213) for therapeutic applications. These acquired data are obtained using alternative production routes compared to the commonly used. Data related to the contaminants produced during the irradiations were also extracted. The experimental cross section values are compared with theoretical model predictions. The large set of data obtained contributes to the theoretical physicist studies allowing to constrain their models to improve and/or validate them. (author)

  16. Multi-routing planning design of Y-type urban rail transit

    Directory of Open Access Journals (Sweden)

    Xinmiao Zhao

    2016-08-01

    Full Text Available A Y-type urban rail transit is composed of a trunk and a branch, and the passenger demand has the characteristics of multidirectional and unbalanced. It is important to design routing planning of Y-type urban rail transit and provide reasonable service for passengers with acceptable operational cost. In this study, a routing planning design model was proposed for Y-type urban rail transit aimed at minimizing the passenger travel time and train operating distance. The decision variables of the model were the locations of turn-backs and the departure frequencies of the train routings in the multi-routing planning. The constraints of passenger demand and line condition were considered. The multi-objective model was turned into a single-objective model by giving weight values to the objectives. Then a genetic algorithm was applied to obtain optimal solutions of the proposed model. Finally, a case study was conducted, and the optimal solutions under different forms of multi-routing planning with different weight values were analyzed. The results showed that when the weight of the passenger travel time increased to a certain level, the optimal solution changed from a two-routing planning to a three-routing planning, and the latter one could better meet the characteristics of the passenger.

  17. Ship Pipe Routing Design Using NSGA-II and Coevolutionary Algorithm

    Directory of Open Access Journals (Sweden)

    Wentie Niu

    2016-01-01

    Full Text Available Pipe route design plays a prominent role in ship design. Due to the complex configuration in layout space with numerous pipelines, diverse design constraints, and obstacles, it is a complicated and time-consuming process to obtain the optimal route of ship pipes. In this article, an optimized design method for branch pipe routing is proposed to improve design efficiency and to reduce human errors. By simplifying equipment and ship hull models and dividing workspace into three-dimensional grid cells, the mathematic model of layout space is constructed. Based on the proposed concept of pipe grading method, the optimization model of pipe routing is established. Then an optimization procedure is presented to deal with pipe route planning problem by combining maze algorithm (MA, nondominated sorting genetic algorithm II (NSGA-II, and cooperative coevolutionary nondominated sorting genetic algorithm II (CCNSGA-II. To improve the performance in genetic algorithm procedure, a fixed-length encoding method is presented based on improved maze algorithm and adaptive region strategy. Fuzzy set theory is employed to extract the best compromise pipeline from Pareto optimal solutions. Simulation test of branch pipe and design optimization of a fuel piping system were carried out to illustrate the design optimization procedure in detail and to verify the feasibility and effectiveness of the proposed methodology.

  18. Computer-aided design for routing of in-core instrumentation guide tubes

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sung Ho; Sohn, Yong Soo; Yoon, Ki Seok; Cho, Duk Sang; Sung, Ki Kwang [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1993-07-01

    This study presents a computer design program for in-core instrumentation (ICI) guide tube routing and locations on support system, and checking the interference between ICI guide tubes in the reactor coolant system of typical pressurized water reactor. The simulation program called ICITRIC(in-core instrumentation tube routing and interference check), has been developed for routing of ICI guide tubes, locations on support system, and checking the interference between ICI guide tubes. The program, ICITRIC, has been written in FORTRAN 77 language which is available under UNIX environment. Results of this program are compared with those of the commercial code, PATRAN, and both results are almost same. Also the results may provide input data for ICI system static and dynamic analysis performed by the commercial code, SUPERPIPE. Through a process of iteration, the designer can apply initial conditions, and modify the routing until satisfied with the overall system performance. (Author) 15 refs., 10 figs., 10 tabs.

  19. Design and Analysis of Secure Routing Protocol for Wireless Sensor Networks

    Science.gov (United States)

    Wang, Jiong; Zhang, Hua

    2017-09-01

    In recent years, with the development of science and technology and the progress of the times, China's wireless network technology has become increasingly prosperous and it plays an important role in social production and life. In this context, in order to further to enhance the stability of wireless network data transmission and security enhancements, the staff need to focus on routing security and carry out related work. Based on this, this paper analyzes the design of wireless sensor based on secure routing protocol.

  20. Design of Logistics Route Planning for Printing Enterprises Based on Baidu Map

    Directory of Open Access Journals (Sweden)

    Da Zhong-Yue

    2017-01-01

    Full Text Available As traditional printing industry is facing fierce competition in the market and logistics becomes a new sources of growth, the traditional printing enterprises want to build and improve their logistics system. So in this paper, the author has designed the logistics planning system based on the Baidu map development kit. It has the function of route planning and location tracking. This system meet the printing enterprise logistics route planning and tracking demand.

  1. Analog integrated circuit design automation placement, routing and parasitic extraction techniques

    CERN Document Server

    Martins, Ricardo; Horta, Nuno

    2017-01-01

    This book introduces readers to a variety of tools for analog layout design automation. After discussing the placement and routing problem in electronic design automation (EDA), the authors overview a variety of automatic layout generation tools, as well as the most recent advances in analog layout-aware circuit sizing. The discussion includes different methods for automatic placement (a template-based Placer and an optimization-based Placer), a fully-automatic Router and an empirical-based Parasitic Extractor. The concepts and algorithms of all the modules are thoroughly described, enabling readers to reproduce the methodologies, improve the quality of their designs, or use them as starting point for a new tool. All the methods described are applied to practical examples for a 130nm design process, as well as placement and routing benchmark sets. Introduces readers to hierarchical combination of Pareto fronts of placements; Presents electromigration-aware routing with multilayer multiport terminal structures...

  2. 40 CFR 60.4111 - Alternate Hg designated representative.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Alternate Hg designated representative... Times for Coal-Fired Electric Steam Generating Units Hg Designated Representative for Hg Budget Sources § 60.4111 Alternate Hg designated representative. (a) A certificate of representation under § 60.4113...

  3. A Cross-Layer Routing Design for Multi-Interface Wireless Mesh Networks

    Directory of Open Access Journals (Sweden)

    Tzu-Chieh Tsai

    2009-01-01

    Full Text Available In recent years, Wireless Mesh Networks (WMNs technologies have received significant attentions. WMNs not only accede to the advantages of ad hoc networks but also provide hierarchical multi-interface architecture. Transmission power control and routing path selections are critical issues in the past researches of multihop networks. Variable transmission power levels lead to different network connectivity and interference. Further, routing path selections among different radio interfaces will also produce different intra-/interflow interference. These features tightly affect the network performance. Most of the related works on the routing protocol design do not consider transmission power control and multi-interface environment simultaneously. In this paper, we proposed a cross-layer routing protocol called M2iRi2 which coordinates transmission power control and intra-/interflow interference considerations as routing metrics. Each radio interface calculates the potential tolerable-added transmission interference in the physical layer. When the route discovery starts, the M2iRi2 will adopt the appropriate power level to evaluate each interface quality along paths. The simulation results demonstrate that our design can enhance both network throughput and end-to-end delay.

  4. Joint Channel Assignment and Routing in Multiradio Multichannel Wireless Mesh Networks: Design Considerations and Approaches

    Directory of Open Access Journals (Sweden)

    Omar M. Zakaria

    2016-01-01

    Full Text Available Multiradio wireless mesh network is a promising architecture that improves the network capacity by exploiting multiple radio channels concurrently. Channel assignment and routing are underlying challenges in multiradio architectures since both determine the traffic distribution over links and channels. The interdependency between channel assignments and routing promotes toward the joint solutions for efficient configurations. This paper presents an in-depth review of the joint approaches of channel assignment and routing in multiradio wireless mesh networks. First, the key design issues, modeling, and approaches are identified and discussed. Second, existing algorithms for joint channel assignment and routing are presented and classified based on the channel assignment types. Furthermore, the set of reconfiguration algorithms to adapt the network traffic dynamics is also discussed. Finally, the paper presents some multiradio practical implementations and test-beds and points out the future research directions.

  5. ReRouting biomedical innovation: observations from a mapping of the alternative research and development (R&D) landscape.

    Science.gov (United States)

    Greenberg, Alexandra; Kiddell-Monroe, Rachel

    2016-09-14

    In recent years, the world has witnessed the tragic outcomes of multiple global health crises. From Ebola to high prices to antibiotic resistance, these events highlight the fundamental constraints of the current biomedical research and development (R&D) system in responding to patient needs globally.To mitigate this lack of responsiveness, over 100 self-identified "alternative" R&D initiatives, have emerged in the past 15 years. To begin to make sense of this panoply of initiatives working to overcome the constraints of the current system, UAEM began an extensive, though not comprehensive, mapping of the alternative biomedical R&D landscape. We developed a two phase approach: (1) an investigation, via the RE:Route Mapping, of both existing and proposed initiatives that claim to offer an alternative approach to R&D, and (2) evaluation of those initiatives to determine which are in fact achieving increased access to and innovation in medicines. Through phase 1, the RE:Route Mapping, we examined 81 initiatives that claim to redress the inequity perpetuated by the current system via one of five commonly recognized mechanisms necessary for truly alternative R&D.Preliminary analysis of phase 1 provides the following conclusions: 1. No initiative presents a completely alternative model of biomedical R&D. 2. The majority of initiatives focus on developing incentives for drug discovery. 3. The majority of initiatives focus on rare diseases or diseases of the poor and marginalized. 4. There is an increasing emphasis on the use of push, pull, pool, collaboration and open mechanisms alongside the concept of delinkage in alternative R&D. 5. There is a trend towards public funding and launching of initiatives by the Global South. Given the RE:Route Mapping's inevitable limitations and the assumptions made in its methodology, it is not intended to be the final word on a constantly evolving and complex field; however, its findings are significant. The Mapping's value lies in its

  6. The Balanced Cross-Layer Design Routing Algorithm in Wireless Sensor Networks Using Fuzzy Logic.

    Science.gov (United States)

    Li, Ning; Martínez, José-Fernán; Hernández Díaz, Vicente

    2015-08-10

    Recently, the cross-layer design for the wireless sensor network communication protocol has become more and more important and popular. Considering the disadvantages of the traditional cross-layer routing algorithms, in this paper we propose a new fuzzy logic-based routing algorithm, named the Balanced Cross-layer Fuzzy Logic (BCFL) routing algorithm. In BCFL, we use the cross-layer parameters' dispersion as the fuzzy logic inference system inputs. Moreover, we give each cross-layer parameter a dynamic weight according the value of the dispersion. For getting a balanced solution, the parameter whose dispersion is large will have small weight, and vice versa. In order to compare it with the traditional cross-layer routing algorithms, BCFL is evaluated through extensive simulations. The simulation results show that the new routing algorithm can handle the multiple constraints without increasing the complexity of the algorithm and can achieve the most balanced performance on selecting the next hop relay node. Moreover, the Balanced Cross-layer Fuzzy Logic routing algorithm can adapt to the dynamic changing of the network conditions and topology effectively.

  7. Templating Routes to Supported Oxide Catalysts by Design

    Energy Technology Data Exchange (ETDEWEB)

    Notestein, Justin M. [Northwestern Univ., Evanston, IL (United States)

    2016-09-08

    The rational design and understanding of supported oxide catalysts requires at least three advancements, in order of increasing complexity: the ability to quantify the number and nature of active sites in a catalytic material, the ability to place external controls on the number and structure of these active sites, and the ability to assemble these active sites so as to carry out more complex functions in tandem. As part of an individual investigator research program that is integrated with the Northwestern University Institute for Catalysis in Energy Processes (ICEP) as of 2015, significant advances were achieved in these three areas. First, phosphonic acids were utilized in the quantitative assessment of the number of active and geometrically-available sites in MOx-SiO2 catalysts, including nanocrystalline composites, co-condensed materials, and grafted structures, for M=Ti, Zr, Hf, Nb, and Ta. That work built off progress in understanding supported Fe, Cu, and Co oxide catalysts from chelating and/or multinuclear precursors to maximize surface reactivity. Secondly, significant progress was made in the new area of using thin oxide overcoats containing ‘nanocavities’ from organic templates as a method to control the dispersion and thermal stability of subsequently deposited metal nanoparticles or other catalytic domains. Similar methods were used to control surface reactivity in SiO2-Al2O3 acid catalysts and to control reactant selectivity in Al2O3-TiO2 photocatalysts. Finally, knowledge gained from the first two areas has been combined to synthesize a tandem catalyst for hydrotreating reactions and an orthogonal tandem catalyst system where two subsequent reactions in a reaction network are independently controlled by light and heat. Overall, work carried out under this project significantly advanced the knowledge of synthesis-structure-function relationships in supported

  8. Mobile Traffic Alert and Tourist Route Guidance System Design Using Geospatial Data

    Science.gov (United States)

    Bhattacharya, D.; Painho, M.; Mishra, S.; Gupta, A.

    2017-09-01

    The present study describes an integrated system for traffic data collection and alert warning. Geographical information based decision making related to traffic destinations and routes is proposed through the design. The system includes a geospatial database having profile relating to a user of a mobile device. The processing and understanding of scanned maps, other digital data input leads to route guidance. The system includes a server configured to receive traffic information relating to a route and location information relating to the mobile device. Server is configured to send a traffic alert to the mobile device when the traffic information and the location information indicate that the mobile device is traveling toward traffic congestion. Proposed system has geospatial and mobile data sets pertaining to Bangalore city in India. It is envisaged to be helpful for touristic purposes as a route guidance and alert relaying information system to tourists for proximity to sites worth seeing in a city they have entered into. The system is modular in architecture and the novelty lies in integration of different modules carrying different technologies for a complete traffic information system. Generic information processing and delivery system has been tested to be functional and speedy under test geospatial domains. In a restricted prototype model with geo-referenced route data required information has been delivered correctly over sustained trials to designated cell numbers, with average time frame of 27.5 seconds, maximum 50 and minimum 5 seconds. Traffic geo-data set trials testing is underway.

  9. MOBILE TRAFFIC ALERT AND TOURIST ROUTE GUIDANCE SYSTEM DESIGN USING GEOSPATIAL DATA

    Directory of Open Access Journals (Sweden)

    D. Bhattacharya

    2017-09-01

    Full Text Available The present study describes an integrated system for traffic data collection and alert warning. Geographical information based decision making related to traffic destinations and routes is proposed through the design. The system includes a geospatial database having profile relating to a user of a mobile device. The processing and understanding of scanned maps, other digital data input leads to route guidance. The system includes a server configured to receive traffic information relating to a route and location information relating to the mobile device. Server is configured to send a traffic alert to the mobile device when the traffic information and the location information indicate that the mobile device is traveling toward traffic congestion. Proposed system has geospatial and mobile data sets pertaining to Bangalore city in India. It is envisaged to be helpful for touristic purposes as a route guidance and alert relaying information system to tourists for proximity to sites worth seeing in a city they have entered into. The system is modular in architecture and the novelty lies in integration of different modules carrying different technologies for a complete traffic information system. Generic information processing and delivery system has been tested to be functional and speedy under test geospatial domains. In a restricted prototype model with geo-referenced route data required information has been delivered correctly over sustained trials to designated cell numbers, with average time frame of 27.5 seconds, maximum 50 and minimum 5 seconds. Traffic geo-data set trials testing is underway.

  10. Refuge alternatives relief valve testing and design

    OpenAIRE

    Lutz, T.J.; Bissert, P.T.; Homce, G.T.; Yonkey, J.A.

    2016-01-01

    The U.S. National Institute for Occupational Safety and Health (NIOSH) has been researching refuge alternatives (RAs) since 2007. RAs typically have built-in pressure relief valves (PRVs) to prevent the unit from reaching unsafe pressures. The U.S. Mine Safety and Health Administration requires that these valves vent the chamber at a maximum pressure of 1.25 kPa (0.18 psi, 5.0 in. H2O), or as specified by the manufacturer, above mine atmospheric pressure in the RA. To facilitate PRV testing, ...

  11. Compact OXC architecture, design and prototype development for flexible waveband routing optical networks.

    Science.gov (United States)

    Ishikawa, Tomohiro; Mori, Yojiro; Hasegawa, Hiroshi; Subramaniam, Suresh; Sato, Ken-Ichi; Moriwaki, Osamu

    2017-07-10

    A novel compact OXC node architecture that combines WSSs and arrays of small scale optical delivery-coupling type switches ("DCSWs") is proposed. Unlike conventional OXC nodes, the WSSs are only responsible for dynamic path bundling ("flexible waveband") while the small scale optical switches route bundled path groups. A network design algorithm that is aware of the routing scheme is also proposed, and numerical experiments elucidate that the necessary number of WSSs and amplifiers can be significantly reduced. A prototype of the proposed OXC is also developed using monolithic arrayed DCSWs. Transmission experiments on the prototype verify the proposal's technical feasibility.

  12. Design Alternative Evaluation No. 3: Post-Closure Ventilation

    International Nuclear Information System (INIS)

    Logan, R.C.

    1999-01-01

    The objective of this study is to provide input to the Enhanced Design Alternatives (EDA) for License Application Design Selection (LADS). Its purpose is to develop and evaluate conceptual designs for post-closure ventilation alternatives that enhance repository performance. Post-closure ventilation is expected to enhance repository performance by limiting the amount of water contacting the waste packages. Limiting the amount of water contacting the waste packages will reduce corrosion

  13. DESIGNING DAILY PATROL ROUTES FOR POLICING BASED ON ANT COLONY ALGORITHM

    Directory of Open Access Journals (Sweden)

    H. Chen

    2015-07-01

    Full Text Available In this paper, we address the problem of planning police patrol routes to regularly cover street segments of high crime density (hotspots with limited police forces. A good patrolling strategy is required to minimise the average time lag between two consecutive visits to hotspots, as well as coordinating multiple patrollers and imparting unpredictability in patrol routes. Previous studies have designed different police patrol strategies for routing police patrol, but these strategies have difficulty in generalising to real patrolling and meeting various requirements. In this research we develop a new police patrolling strategy based on Bayesian method and ant colony algorithm. In this strategy, virtual marker (pheromone is laid to mark the visiting history of each crime hotspot, and patrollers continuously decide which hotspot to patrol next based on pheromone level and other variables. Simulation results using real data testifies the effective, scalable, unpredictable and extensible nature of this strategy.

  14. Early Site Permit Demonstration Program: Station design alternatives report

    International Nuclear Information System (INIS)

    1993-03-01

    This report provides the results of investigating the basis for including Station Design Alternatives (SDAs) in the regulatory guidance given for nuclear plant environmental reports (ERs), explains approaches or processes for evaluating SDAs at the early site permit (ESP) stage, and applies one of the processes to each of the ten systems or subsystems considered as SDAS. The key objective o this report s to demonstrate an adequate examination of alternatives can be performed without the extensive development f design data. The report discusses the Composite Suitability Approach and the Established Cutoff Approach in evaluating station design alternatives and selects one of these approaches to evaluate alternatives for each of the plant or station that were considered. Four types of ALWRs have been considered due to the availability of extensive plant data: System 80+, AP600, Advanced Boiling Reactor (ABWR), and Simplified Boiling Water Reactor (SBWR). This report demonstrates the feasibility of evaluating station design alternatives when reactor design detail has not been determined, quantitatively compares the potential ental impacts of alternatives, and focuses the ultimate selection of a alternative on cost and applicant-specific factors. The range of alternatives system is deliberately limited to a reasonable number to demonstrate the or to the three most commonly used at operating plants

  15. Alternate cap designs under RCRA regulations

    International Nuclear Information System (INIS)

    Manrod, W.E. III; Yager, R.E.; Craig, P.M.

    1988-01-01

    Low-level radioactive waste and mixed wastes have been disposed of in several sites in the vicinity of the Oak Ridge Y-12 Plant in Tennessee. Most of these materials have been placed in shallow land burial pits (SLB). Closure plans have been developed and approved by appropriate regulatory agencies for several of these sites. A variety of cap (final cover) designs for closure of these sites were investigated to determine their ability to inhibit infiltration of precipitation to the waste. The most effective designs are those that use synthetic materials as drainage layers and/or impermeable liners. The more complex, multi-layer systems perform no better than simpler covers and would complicate construction and increase costs. Despite the successful analytical results described in this paper, additional considerations must be factored into use of geosynthetic as well as natural materials

  16. CULTURAL EXPLORATION AS ALTER/NATIVE1 ROUTE TO NATIONAL DEVELOPMENT: INSIGHTS FROM YORUBA VERBAL ARTS

    Directory of Open Access Journals (Sweden)

    OLUWOLE COKER

    2009-01-01

    Full Text Available This paper interrogates Yoruba verbal arts and situates culture as a catalyst for development. It is suggested that the intricate resources of oral art, exemplified by Yoruba textual references, are viable ingredients for socio-cultural empowerment. To fully comprehend the dynamics of a society in constant change due to external and internal realities, one must reconsider culture in order to reposition the society. The multidimensional and multidisciplinary significance of Yoruba verbal art demonstrate that culture has a vital role to play in any meaningful socio-political advancement in the Nigerian body polity. The ideas conveyed in proverbial expressions, representing key cultural realities of the Yoruba people, offer insights and ideas for development and social good. The paper submits that a deeper exploration of the intricate resources of verbal art is a viable route to development.

  17. Enhancing Energy Efficiency of Wireless Sensor Network through the Design of Energy Efficient Routing Protocol

    Directory of Open Access Journals (Sweden)

    Noor Zaman

    2016-01-01

    Full Text Available Wireless Sensor Network (WSN is known to be a highly resource constrained class of network where energy consumption is one of the prime concerns. In this research, a cross layer design methodology was adopted to design an energy efficient routing protocol entitled “Position Responsive Routing Protocol” (PRRP. PRRP is designed to minimize energy consumed in each node by (1 reducing the amount of time in which a sensor node is in an idle listening state and (2 reducing the average communication distance over the network. The performance of the proposed PRRP was critically evaluated in the context of network lifetime, throughput, and energy consumption of the network per individual basis and per data packet basis. The research results were analyzed and benchmarked against the well-known LEACH and CELRP protocols. The outcomes show a significant improvement in the WSN in terms of energy efficiency and the overall performance of WSN.

  18. Insights Gained from Testing Alternate Cell Designs

    International Nuclear Information System (INIS)

    O'Brien, J.E.; Stoots, C.M.; Herring, J.S.; Housley, G.K.; Sohal, M.S.; Milobar, D.G.; Cable, Thomas

    2009-01-01

    The Idaho National Laboratory (INL) has been researching the application of solid-oxide electrolysis cell for large-scale hydrogen production from steam over a temperature range of 800 to 900 C. The INL has been testing various solid oxide cell designs to characterize their electrolytic performance operating in the electrolysis mode for hydrogen production. Some results presented in this report were obtained from cells, initially developed by the Forschungszentrum Juelich and now manufactured by the French ceramics firm St. Gobain. These cells have an active area of 16 cm2 per cell. They were initially developed as fuel cells, but are being tested as electrolytic cells in the INL test stands. The electrolysis cells are electrode-supported, with ∼10 (micro)m thick yttria-stabilized zirconia (YSZ) electrolytes, ∼1400 (micro)m thick nickel-YSZ steam-hydrogen electrodes, and manganite (LSM) air-oxygen electrodes. The experiments were performed over a range of steam inlet mole fractions (0.1 to 0.6), gas flow rates, and current densities (0 to 0.6 A/cm2). Steam consumption rates associated with electrolysis were measured directly using inlet and outlet dewpoint instrumentation. On a molar basis, the steam consumption rate is equal to the hydrogen production rate. Cell performance was evaluated by performing DC potential sweeps at 800, 850, and 900 C. The voltage-current characteristics are presented, along with values of area-specific resistance as a function of current density. Long-term cell performance is also assessed to evaluate cell degradation. Details of the custom single-cell test apparatus developed for these experiments are also presented. NASA, in conjunction with the University of Toledo, has developed another fuel cell concept with the goals of reduced weight and high power density. The NASA cell is structurally symmetrical, with both electrodes supporting the thin electrolyte and containing micro-channels for gas diffusion. This configuration is

  19. Supporting Exploration of Design Alternatives using Multivariate Analysis Algorithms

    NARCIS (Netherlands)

    Šileryte, R.; D'Aquilio, A.; Di Stefano, D.; Yang, D.; Turrin, M.; Attar, Ramtin; Chronis, Angelos; Hanna, Sean; Turrin, Michela

    2016-01-01

    Parametric modelling allows quick generation of a large number of design alternatives. Ultimately, it can be combined with optimization algorithms for obtaining optimal performance-driven design. However, setup of design space for optimization is a very complex task requiring designer’s a priori

  20. 40 CFR 72.22 - Alternate designated representative.

    Science.gov (United States)

    2010-07-01

    ... designated representative is selected shall include a procedure for the owners and operators of the source and affected units at the source to authorize the alternate designated representative to act in lieu...) In the event of a conflict, any action taken by the designated representative shall take precedence...

  1. Comparison of different SFL design alternatives

    International Nuclear Information System (INIS)

    Ivars Neretnieks, Ivars; Moreno, Luis

    2013-04-01

    Four different design options for a repository for long-lived nuclear waste from the future dismantling of the nuclear power plants have been compared. The time scales considered range up to 100,000 years. The repository is to be located at about 500 m depth in granitic rock. The vault can be a tunnel about 200 m long and on the order of 15 X 15 meters, in which the waste is surrounded by either a hydraulic cage, a concrete buffer or a bentonite buffer about 2 m thick. A fourth option is to make a silo, called Supersilo, about as high as wide, surrounded by both concrete and bentonite. In order to compare potential release rates of radionuclides from the waste to the seeping water in the rock a number of simple models have been devised. Some of these models allow the water flow rates through vaults to be assessed under various conditions and configurations. Other models are used to calculate the uptake by molecular diffusion to the water in the rock that seeps past the vaults. Moreover other models are used to calculate the rate of transport of nuclides by diffusion and flow through the buffer and waste. The decay of the nuclides during their passage from the waste to the flowing water through and past the vaults is accounted for. Many nuclides of interest decay considerably in the buffer. The mathematical form of the models is made so simple that essentially hand calculations can be used to explore the strength of different barriers and design options. The simple models are validated against more complex coupled models accounting for simultaneously competing processes. The more complex models are solved by numerical methods. The toolbox of simple models is used to calculate the strength of the barriers in the different design options under various conditions. Examples of activity releases of three nuclides with different sorption characteristics and half-lives are presented. It is found that a hydraulic cage is not a good option as it promotes the release of

  2. Comparison of different SFL design alternatives

    Energy Technology Data Exchange (ETDEWEB)

    Ivars Neretnieks, Ivars [Chemima AB, Taeby (Sweden); Moreno, Luis [LMQuimica, Vaarby (Sweden)

    2013-04-15

    Four different design options for a repository for long-lived nuclear waste from the future dismantling of the nuclear power plants have been compared. The time scales considered range up to 100,000 years. The repository is to be located at about 500 m depth in granitic rock. The vault can be a tunnel about 200 m long and on the order of 15 X 15 meters, in which the waste is surrounded by either a hydraulic cage, a concrete buffer or a bentonite buffer about 2 m thick. A fourth option is to make a silo, called Supersilo, about as high as wide, surrounded by both concrete and bentonite. In order to compare potential release rates of radionuclides from the waste to the seeping water in the rock a number of simple models have been devised. Some of these models allow the water flow rates through vaults to be assessed under various conditions and configurations. Other models are used to calculate the uptake by molecular diffusion to the water in the rock that seeps past the vaults. Moreover other models are used to calculate the rate of transport of nuclides by diffusion and flow through the buffer and waste. The decay of the nuclides during their passage from the waste to the flowing water through and past the vaults is accounted for. Many nuclides of interest decay considerably in the buffer. The mathematical form of the models is made so simple that essentially hand calculations can be used to explore the strength of different barriers and design options. The simple models are validated against more complex coupled models accounting for simultaneously competing processes. The more complex models are solved by numerical methods. The toolbox of simple models is used to calculate the strength of the barriers in the different design options under various conditions. Examples of activity releases of three nuclides with different sorption characteristics and half-lives are presented. It is found that a hydraulic cage is not a good option as it promotes the release of

  3. Design of a covert RFID tag network for target discovery and target information routing.

    Science.gov (United States)

    Pan, Qihe; Narayanan, Ram M

    2011-01-01

    Radio frequency identification (RFID) tags are small electronic devices working in the radio frequency range. They use wireless radio communications to automatically identify objects or people without the need for line-of-sight or contact, and are widely used in inventory tracking, object location, environmental monitoring. This paper presents a design of a covert RFID tag network for target discovery and target information routing. In the design, a static or very slowly moving target in the field of RFID tags transmits a distinct pseudo-noise signal, and the RFID tags in the network collect the target information and route it to the command center. A map of each RFID tag's location is saved at command center, which can determine where a RFID tag is located based on each RFID tag's ID. We propose the target information collection method with target association and clustering, and we also propose the information routing algorithm within the RFID tag network. The design and operation of the proposed algorithms are illustrated through examples. Simulation results demonstrate the effectiveness of the design.

  4. Design of a Covert RFID Tag Network for Target Discovery and Target Information Routing

    Directory of Open Access Journals (Sweden)

    Qihe Pan

    2011-09-01

    Full Text Available Radio frequency identification (RFID tags are small electronic devices working in the radio frequency range. They use wireless radio communications to automatically identify objects or people without the need for line-of-sight or contact, and are widely used in inventory tracking, object location, environmental monitoring. This paper presents a design of a covert RFID tag network for target discovery and target information routing. In the design, a static or very slowly moving target in the field of RFID tags transmits a distinct pseudo-noise signal, and the RFID tags in the network collect the target information and route it to the command center. A map of each RFID tag’s location is saved at command center, which can determine where a RFID tag is located based on each RFID tag’s ID. We propose the target information collection method with target association and clustering, and we also propose the information routing algorithm within the RFID tag network. The design and operation of the proposed algorithms are illustrated through examples. Simulation results demonstrate the effectiveness of the design.

  5. 31 CFR 0.104 - Designated Agency Ethics Official and Alternate Designated Agency Ethics Official.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Designated Agency Ethics Official and Alternate Designated Agency Ethics Official. 0.104 Section 0.104 Money and Finance: Treasury Office of the... Responsibilities § 0.104 Designated Agency Ethics Official and Alternate Designated Agency Ethics Official. The...

  6. Parametric 'route structure' generation and analysis : An interactive design system application for urban design

    NARCIS (Netherlands)

    Beirao, J.N.; Nourian Ghadikolaee, P.; Van Walderveen, B.

    2011-01-01

    Marshall (2005) developed the concept of characteristic structure of a street network as a characteristic set of indicators extracted from the street network through a process which he called “route structure analysis”. In this paper we propose an integrated process for street network generation and

  7. Alternative route for the MDW project for automotive fuels in the Dutch highway sector. A legal analysis

    International Nuclear Information System (INIS)

    Van Haute, J.S.R.; Kooy, J.

    2002-01-01

    In February 1998, the Dutch Government initiated an MDW project ('Marktwerking, Deregulering en Wetgevingskwaliteit', i.e. market functioning, deregulation and quality of legislation) to review ways in which competition within the motorway segment of the Dutch retail fuel market could be improved. The project reviewed the entry barriers and considered ways to stimulate competition, including preferential treatment of new entrants. The Dutch Major oil companies protested against the original plans of the Government and announced legal proceedings. The Government agreed to engage in negotiations with the oil industry in order to reach a compromise solution and avoid a legal battle. This resulted in an alternative route, which is analyzed in this article from a legal perspective [nl

  8. The design, fabrication and installation of cable routing mockups in support of Spacelab 2

    Science.gov (United States)

    1981-01-01

    From flight and mockup drawings of Spacelab 2 (SL 2) experiments and hardware, shop ready mockup drawings were produced. Floor panels were the first items considered for fabrication. Cold plate and orthogrid mockups were designed and fabricated. Experiment and other hardware mockups were fabricated of aluminum or plywood, depending on size and configuration. Eighty-three cable routing bracket mockups were fabricated of aluminum and delivered for painting.

  9. Subsurface barrier design alternatives for confinement and controlled advection flow

    International Nuclear Information System (INIS)

    Phillips, S.J.; Stewart, W.E.; Alexander, R.G.; Cantrell, K.J.; McLaughlin, T.J.

    1994-02-01

    Various technologies and designs are being considered to serve as subsurface barriers to confine or control contaminant migration from underground waste storage or disposal structures containing radioactive and hazardous wastes. Alternatives including direct-coupled flood and controlled advection designs are described as preconceptual examples. Prototype geotechnical equipment for testing and demonstration of these alternative designs tested at the Hanford Geotechnical Development and Test Facility and the Hanford Small-Tube Lysimeter Facility include mobile high-pressure injectors and pumps, mobile transport and pumping units, vibratory and impact pile drivers, and mobile batching systems. Preliminary laboratory testing of barrier materials and additive sequestering agents have been completed and are described

  10. 76 FR 37059 - Siuslaw National Forest; Oregon; Oregon Dunes NRA Management Area 10 (C) Route and Area Designation

    Science.gov (United States)

    2011-06-24

    ... Off Road Vehicle (ORV) routes within Management Area (MA) 10 (C) of the Oregon Dunes National... Management Area 10 (C) Route and Area Designation AGENCY: Forest Service, USDA. ACTION: Notice of intent to... impact statement (EIS) to amend the 1990 Siuslaw National Forest Land and Resources Management Plan (as...

  11. 29 CFR 2703.2 - Designated agency ethics official and alternate designated agency ethics official.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Designated agency ethics official and alternate designated agency ethics official. 2703.2 Section 2703.2 Labor Regulations Relating to Labor (Continued) FEDERAL... agency ethics official and alternate designated agency ethics official. The Chairman shall appoint an...

  12. AN ALTERNATIVE ROUTE TO PRODUCE STANDARDS FOR GEL PERMEATION CHROMATOGRAPHY USING NITROXIDE MEDIATED POLYMERIZATION

    Directory of Open Access Journals (Sweden)

    C. P. R. Malere

    Full Text Available Abstract All over the world standards for Gel Permeation Chromatography (GPC are produced using ionic polymerization. Standards are commercialized in a broad range of molecular weight and their dispersity (Ð must be lower than 1.1. This work proposes the synthesis of polystyrene standards using Nitroxide Mediated Polymerization (NMP, an alternative technique to produce controlled polymers that is much more robust when compared to ionic polymerization. Standards with different ranges of molecular weights were obtained, all of them with very narrow molecular weight distribution (MWD and dispersity (Ð lower than 1.10. In order to do that, several combinations of different initiators were tested. Advanced GPC Triple Detector was used to obtain important properties, such as absolute number and weight average molecular weights, dispersity and intrinsic viscosity. The analytical method used in the characterization of the samples was in-house validated in terms of linearity, accuracy, precision, repeatability and robustness. The validation study demonstrated the quality of the measurements and ensured that the information obtained for a given analyte by the GPC technique is reliable.

  13. An Alternative Route to Teaching Fraction Division: Abstraction of Common Denominator Algorithm

    Directory of Open Access Journals (Sweden)

    İsmail Özgür ZEMBAT

    2015-06-01

    Full Text Available From a curricular stand point, the traditional invert and multiply algorithm for division of fractions provides few affordances for linking to a rich understanding of fractions. On the other hand, an alternative algorithm, called common denominator algorithm, has many such affordances. The current study serves as an argument for shifting curriculum for fraction division from use of invert and multiply algorithm as a basis to the use of common denominator algorithm as a basis. This was accomplished with the analysis of learning of two prospective elementary teachers being an illustration of how to realize those conceptual affordances. In doing so, the article proposes an instructional sequence and details it by referring to both the (mathematical and pedagogical advantages and the disadvantages. As a result, this algorithm has a conceptual basis depending on basic operations of partitioning, unitizing, and counting, which make it accessible to learners. Also, when participants are encouraged to construct this algorithm based on their work with diagrams, common denominator algorithm formalizes the work that they do with diagrams.

  14. An alternative route to teaching fraction division: Abstraction of common denominator algorithm

    Directory of Open Access Journals (Sweden)

    İsmail Özgür Zembat

    2015-07-01

    Full Text Available From a curricular stand point, the traditional invert and multiply algorithm for division of fractions provides few affordances for linking to a rich understanding of fractions. On the other hand, an alternative algorithm, called common denominator algorithm, has many such affordances. The current study serves as an argument for shifting curriculum for fraction division from use of invert and multiply algorithm as a basis to the use of common denominator algorithm as a basis. This was accomplished with the analysis of learning of two prospective elementary teachers being an illustration of how to realize those conceptual affordances. In doing so, the article proposes an instructional sequence and details it by referring to both the (mathematical and pedagogical advantages and the disadvantages. As a result, this algorithm has a conceptual basis depending on basic operations of partitioning, unitizing, and counting, which make it accessible to learners. Also, when participants are encouraged to construct this algorithm based on their work with diagrams, common denominator algorithm formalizes the work that they do with diagrams.

  15. Tunneling nanotubes: an alternate route for propagation of the bystander effect following oncolytic viral infection

    Directory of Open Access Journals (Sweden)

    Justin Ady

    2016-01-01

    Full Text Available Tunneling nanotubes (TNTs are ultrafine, filamentous actin-based cytoplasmic extensions which form spontaneously to connect cells at short and long-range distances. We have previously described long-range intercellular communication via TNTs connecting mesothelioma cells in vitro and demonstrated TNTs in intact tumors from patients with mesothelioma. Here, we investigate the ability of TNTs to mediate a viral thymidine kinase based bystander effect after oncolytic viral infection and administration of the nucleoside analog ganciclovir. Using confocal microscopy we assessed the ability of TNTs to propagate enhanced green fluorescent protein (eGFP, which is encoded by the herpes simplex virus NV1066, from infected to uninfected recipient cells. Using time-lapse imaging, we observed eGFP expressed in infected cells being transferred via TNTs to noninfected cells; additionally, increasing fluorescent activity in recipient cells indicated cell-to-cell transmission of the eGFP-expressing NV1066 virus had also occurred. TNTs mediated cell death as a form of direct cell-to-cell transfer following viral thymidine kinase mediated activation of ganciclovir, inducing a unique long-range form of the bystander effect through transmission of activated ganciclovir to nonvirus-infected cells. Thus, we provide proof-of-principle demonstration of a previously unknown and alternative mechanism for inducing apoptosis in noninfected recipient cells. The conceptual advance of this work is that TNTs can be harnessed for delivery of oncolytic viruses and of viral thymidine kinase activated drugs to amplify the bystander effect between cancer cells over long distances in stroma-rich tumor microenvironments.

  16. Design alternatives report for the cesium removal demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Walker, J.F. Jr.; Youngblood, E.L.

    1995-09-01

    The Cesium Removal Demonstration (CRD) project will use liquid low-level waste (LLLW) stored in the Oak Ridge National Laboratory Melton Valley Storage Tanks to demonstrate cesium removal from sodium nitrate-based supernates. This report presents the results of a conceptual design study to scope the alternatives for conducting the demonstration at ORNL. Factors considered included (1) sorbent alternatives, (2) facility alternatives, (3) process alternatives, (4) process disposal alternatives, and (5) relative cost comparisons. Recommendations included (1) that design of the CRD system move forward based on information obtained to date from tests with Savannah River Resin, (2) that the CRD system be designed so it could use crystalline silicotitanates (CST) if an engineered form of CST becomes available prior to the CRD, (3) that the system be designed without the capability for resin regeneration, (4) that the LLLW solidification facility be used for the demonstration (5) that vitrification of the loaded resins from the CRD be demonstrated at the Savannah River Site, and (6) that permanent disposal of the loaded and/or vitrified resin at the Nevada Test Site be pursued.

  17. Design alternatives report for the cesium removal demonstration

    International Nuclear Information System (INIS)

    Walker, J.F. Jr.; Youngblood, E.L.

    1995-09-01

    The Cesium Removal Demonstration (CRD) project will use liquid low-level waste (LLLW) stored in the Oak Ridge National Laboratory Melton Valley Storage Tanks to demonstrate cesium removal from sodium nitrate-based supernates. This report presents the results of a conceptual design study to scope the alternatives for conducting the demonstration at ORNL. Factors considered included (1) sorbent alternatives, (2) facility alternatives, (3) process alternatives, (4) process disposal alternatives, and (5) relative cost comparisons. Recommendations included (1) that design of the CRD system move forward based on information obtained to date from tests with Savannah River Resin, (2) that the CRD system be designed so it could use crystalline silicotitanates (CST) if an engineered form of CST becomes available prior to the CRD, (3) that the system be designed without the capability for resin regeneration, (4) that the LLLW solidification facility be used for the demonstration (5) that vitrification of the loaded resins from the CRD be demonstrated at the Savannah River Site, and (6) that permanent disposal of the loaded and/or vitrified resin at the Nevada Test Site be pursued

  18. The gluconate shunt is an alternative route for directing glucose into the pentose phosphate pathway in fission yeast.

    Science.gov (United States)

    Corkins, Mark E; Wilson, Stevin; Cocuron, Jean-Christophe; Alonso, Ana P; Bird, Amanda J

    2017-08-18

    Glycolysis and the pentose phosphate pathway both play a central role in the degradation of glucose in all domains of life. Another metabolic route that can facilitate glucose breakdown is the gluconate shunt. In this shunt glucose dehydrogenase and gluconate kinase catalyze the two-step conversion of glucose into the pentose phosphate pathway intermediate 6-phosphogluconate. Despite the presence of these enzymes in many organisms, their only established role is in the production of 6-phosphogluconate for the Entner-Doudoroff pathway. In this report we performed metabolic profiling on a strain of Schizosaccharomyces pombe lacking the zinc-responsive transcriptional repressor Loz1 with the goal of identifying metabolic pathways that were altered by cellular zinc status. This profiling revealed that loz1 Δ cells accumulate higher levels of gluconate. We show that the altered gluconate levels in loz1 Δ cells result from increased expression of gcd1 By analyzing the activity of recombinant Gcd1 in vitro and by measuring gluconate levels in strains lacking enzymes of the gluconate shunt we demonstrate that Gcd1 encodes a novel NADP + -dependent glucose dehydrogenase that acts in a pathway with the Idn1 gluconate kinase. We also find that cells lacking gcd1 and zwf1 , which encode the first enzyme in the pentose phosphate pathway, have a more severe growth phenotype than cells lacking zwf1 We propose that in S. pombe Gcd1 and Idn1 act together to shunt glucose into the pentose phosphate pathway, creating an alternative route for directing glucose into the pentose phosphate pathway that bypasses hexokinase and the rate-limiting enzyme glucose-6-phosphate dehydrogenase. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  19. Sol-gel coatings: An alternative route for producing planar optical waveguides

    Energy Technology Data Exchange (ETDEWEB)

    Rey-Garcia, F.; Gomez-Reino, C. [Unidad Asociada de Optica and Microoptica GRIN (CSIC-ICMA), Departamento de Fisica Aplicada, Escola Universitaria de Optica e Optometria, Universidade de Santiago de Compostela, Campus Sur s/n, E-15782 Santiago de Compostela (Spain); Flores-Arias, M.T., E-mail: maite.flores@usc.es [Unidad Asociada de Optica and Microoptica GRIN (CSIC-ICMA), Departamento de Fisica Aplicada, Escola Universitaria de Optica e Optometria, Universidade de Santiago de Compostela, Campus Sur s/n, E-15782 Santiago de Compostela (Spain); De La Fuente, G.F., E-mail: xerman@unizar.es [Instituto de Ciencia de Materiales de Aragon (CSIC-Universidad de Zaragoza), Maria de Luna 3, E-50018 Zaragoza (Spain); Duran, A. [Instituto de Ceramica y Vidrio (CSIC), Kelsen 5, E-28049, Madrid (Spain); Castro, Y., E-mail: castro@icv.csic.es [Instituto de Ceramica y Vidrio (CSIC), Kelsen 5, E-28049, Madrid (Spain)

    2011-09-01

    Inorganic and hybrid planar waveguides with different compositions (silica-titania, methacrylate-silica-cerium oxide, zirconia-cerium oxide and silica-zirconia) have been obtained by sol-gel synthesis followed by dip-coating. Soda-lime glass slides and conventional commercial window glass were used as substrates. The thickness and refractive index of the coatings were determined by profilometry and Spectroscopic Ellipsometry. Waveguide efficiency was measured at ca. 70.8% with a He-Ne laser beam, coupled with an optical microscope objective into and out of the waveguiding layer via a double prism configuration. Thicknesses between 150 and 2000 nm, along with refractive index values ranging between 1.45 and {approx} 1.99 ({lambda} = 633 nm) were obtained depending on the sol composition and the dip-coating conditions. This wide range of values allows designing multilayered guides that can be used in a variety of applications.

  20. Alternative design concept for the second Glass Waste Storage Building

    International Nuclear Information System (INIS)

    Rainisch, R.

    1992-10-01

    This document presents an alternative design concept for storing canisters filled with vitrified waste produced at the Defense Waste Processing Facility (DWPF). The existing Glass Waste Storage Building (GWSB1) has the capacity to store 2,262 canisters and is projected to be completely filled by the year 2000. Current plans for glass waste storage are based on constructing a second Glass Waste Storage Building (GWSB2) once the existing Glass Waste Storage Building (GWSB1) is filled to capacity. The GWSB2 project (Project S-2045) is to provide additional storage capacity for 2,262 canisters. This project was initiated with the issue of a basic data report on March 6, 1989. In response to the basic data report Bechtel National, Inc. (BNI) prepared a draft conceptual design report (CDR) for the GWSB2 project in April 1991. In May 1991 WSRC Systems Engineering issued a revised Functional Design Criteria (FDC), the Rev. I document has not yet been approved by DOE. This document proposes an alternative design for the conceptual design (CDR) completed in April 1991. In June 1992 Project Management Department authorized Systems Engineering to further develop the proposed alternative design. The proposed facility will have a storage capacity for 2,268 canisters and will meet DWPF interim storage requirements for a five-year period. This document contains: a description of the proposed facility; a cost estimate of the proposed design; a cost comparison between the proposed facility and the design outlined in the FDC/CDR; and an overall assessment of the alternative design as compared with the reference FDC/CDR design

  1. A flow-first route-next heuristic for liner shipping network design

    DEFF Research Database (Denmark)

    Krogsgaard, Alexander; Pisinger, David; Thorsen, Jesper

    2018-01-01

    Having a well-designed liner shipping network is paramount to ensure competitive freight rates, adequate capacity on trade-lanes, and reasonable transportation times.The most successful algorithms for liner shipping network design make use of a two-phase approach, where they first design the routes...... of the vessels, and then flow the containers through the network in order to calculate how many of the customers’demands can be satisfied, and what the imposed operational costs are. In this article, we reverse the approach by first flowing the containers through a relaxed network, and then design routes to match...... this flow. This gives a better initial solution than starting from scratch, and the relaxed network reflects the ideas behind a physical internet of having a distributed multi-segment intermodal transport. Next, the initial solution is improved by use of a variable neighborhood search method, where six...

  2. Experiencing the Tourist City. The European Capital of Culture in Re-Designing City Routes

    Directory of Open Access Journals (Sweden)

    Manuela Guerreiro

    2014-12-01

    Full Text Available Assuming that providing memorable experiences is the raison d’être of tourism industry, the city envisaged as a tourist destination should assume the tourist’s perspective when designing the settings and the most significant activities of a visit. Cities are facing new challenges, noticeably the globalisation of economies, the growing importance of the visual and the symbolic that define the current trends of consumption and the attractiveness of a place. Culture and events play a strategic role when designing innovative and appealing tourism experiences. The European Capital of Culture (ECoC is an international event which represents a unique opportunity for the cities to stand out in this globalised and competitive scenario. This paper focuses on the study of Pécs, European Capital of Culture 2010, and it aims to study the influence of this event on the design of city tourism routes. A survey by questionnaire was administered to tourists before and during ECoC in Pécs. Respondents indicated in open-ended questions the most outstanding points in their visit to the city, on which were designed the relevant circuits and routes during that tourist experience in Pécs. Data analysis was performed using the statistical software STAS.

  3. Particulate matter exposure along designated bicycle routes in Vancouver, British Columbia.

    Science.gov (United States)

    Thai, Amy; McKendry, Ian; Brauer, Michael

    2008-11-01

    An instrumented bicycle was used to elucidate particulate matter exposures along bicycle routes passing through a variety of land uses over 14 days during summer and fall in a mid-latitude traffic dominated urban setting. Overall, exposures were low or comparable to those found in studies elsewhere (mean PM(2.5) and PM(10) concentrations over each daily bicycle traverse varied between 7-34 microg m(-3) and 26-77 microg m(-3) respectively). Meteorological factors were responsible for significant day-to-day variability with PM(2.5) positively correlated with air temperature, PM(10) negatively correlated with precipitation, and ultrafine particles negatively correlated with both air temperature and wind speed. On individual days, land use and proximity to traffic were factors significantly affecting exposure along designated bicycle routes. While concentrations of PM(2.5) were found to be relatively spatially uniform over the length of the study route, PM(10) showed a more heterogeneous spatial distribution. Specifically, construction sites and areas susceptible to the suspension of road dust have higher concentrations of coarse particles. Ultrafine particles were also heterogeneously distributed in space, with areas with heavy traffic volumes having the highest concentrations. Observations show qualitative agreement in terms of spatial patterns with a land-use regression (LUR) model for annual PM(2.5) concentrations.

  4. A Location-Inventory-Routing Problem in Forward and Reverse Logistics Network Design

    Directory of Open Access Journals (Sweden)

    Qunli Yuchi

    2016-01-01

    Full Text Available We study a new problem of location-inventory-routing in forward and reverse logistic (LIRP-FRL network design, which simultaneously integrates the location decisions of distribution centers (DCs, the inventory policies of opened DCs, and the vehicle routing decision in serving customers, in which new goods are produced and damaged goods are repaired by a manufacturer and then returned to the market to satisfy customers’ demands as new ones. Our objective is to minimize the total costs of manufacturing and remanufacturing goods, building DCs, shipping goods (new or recovered between the manufacturer and opened DCs, and distributing new or recovered goods to customers and ordering and storage costs of goods. A nonlinear integer programming model is proposed to formulate the LIRP-FRL. A new tabu search (NTS algorithm is developed to achieve near optimal solution of the problem. Numerical experiments on the benchmark instances of a simplified version of the LIRP-FRL, the capacitated location routing problem, and the randomly generated LIRP-FRL instances demonstrate the effectiveness and efficiency of the proposed NTS algorithm in problem resolution.

  5. Mucoadhesive microemulsion of ibuprofen: design and evaluation for brain targeting efficiency through intranasal route

    Directory of Open Access Journals (Sweden)

    Surjyanarayan Mandal

    2015-09-01

    Full Text Available This study aimed at designing mucoadhesive microemulsion gel to enhance the brain uptake of Ibuprofen through intranasal route. Ibuprofen loaded mucoadhesive microemulsion (MMEI was developed by incorporating polycarbophil as mucoadhesive polymer into Capmul MCM based optimal microemulsion (MEI and was subjected to characterization, stability, mucoadhesion and naso-ciliotoxicity study. Brain uptake of ibuprofen via nasal route was studied by performing biodistribution study in Swiss albino rats. MEI was found to be transparent, stable and non ciliotoxic with 66.29 ± 4.15 nm, -20.9 ± 3.98 mV and 98.66 ± 1.01% as average globule size, zeta potential and drug content respectively. Transmission Electron Microscopy (TEM study revealed the narrow globule size distribution of MEI. Following single intranasal administration of MMEI and MEI at a dose of 2.86 mg/kg, uptake of ibuprofen in the olfactory bulb was around 3.0 and 1.7 folds compared with intravenous injection of ibuprofen solution (IDS. The ratios of AUC in brain tissues to that in plasma obtained after nasal administration of MMEI were significantly higher than those after intravenous administration of IDS. Findings of the present investigation revealed that the developed mucoadhesive microemulsion gel could be a promising approach for brain targeting of ibuprofen through intranasal route.

  6. Final environmental assessment: Los Reales 115 kV transmission line alternative routes

    Energy Technology Data Exchange (ETDEWEB)

    1989-10-01

    The Central Arizona Project (CAP) was authorized as a part of the Colorado River Basin Project Act (Public Law 90-537) on September 30, 1968. The primary purpose of the CAP is to furnish water for agricultural, municipal, and industrial uses in central and southern Arizona, and western New Mexico. Due to its magnitude, the CAP is divided into several major features serving separate but interrelated functions. The Tucson Aqueduct Phase B pumping plants were designed and constructed to operate on a looped power system. The entire looped power system, including two switching stations and connecting 115-kv transmission lines, was identified in the FEIS and approved for construction in the Secretary of Interior's Record of Decision dated September 24, 1985. The loop begins in the vicinity of the Twin Peaks Pumping Plant -- the northernmost Phase B pumping station, at the Rattlesnake Switching Station. All of the looped power system has been constructed with the exception of the switching station and portion of transmission line proposed to be constructed in this project. Without construction of this final portion of the looped power system, the Phase B pumping plants will not be able to operate normally without negatively affecting nearby power sources. The CAP will also not be able to provide the reliability necessary for municipal water systems dependent upon CAP water. The purpose of this EA is to describe impacts that would result from relocating the Los Reales 115-kV transmission line, and possibly the switching station, originally identified in the FEIS. It should be mentioned the Department of Energy will complete a separate NEPA review.

  7. Integration of social vulnerability into emergency management plans: designing of evacuation routes against flood disasters

    Science.gov (United States)

    Aroca-Jimenez, Estefanía; Bodoque, Jose Maria; Garcia, Juan Antonio; Diez-Herrero, Andres

    2017-04-01

    Flash floods are highly spatio-temporal localized flood events characterized by reaching a high peak flow in a very short period of time, i.e., generally with times of concentration lower than six hours. Its short duration, which limits or even voids any warning time, means that flash floods are considered to be one of the most destructive natural hazards with the greatest capacity to generate risk, either in terms of the number of people affected globally or the proportion of individual fatalities. The above highlights the importance of a realistic and appropriate design of evacuation strategies in order to reduce flood-related losses, being evacuation planning considered of critical importance for disaster management. Traditionally, evacuation maps have been based on flood-prone areas, shelters or emergency residences location and evacuation routes information. However, evacuation plans rarely consider the spatial distribution of vulnerable population (i.e., people with special needs, mobility constraints or economic difficulties), which usually require assistance from emergency responders. The goal of this research is to elaborate an evacuation map against the occurrence of flash floods by combining geographic information (e.g. roads, health facilities location, sanitary helicopters) and social vulnerability patterns, which are previously obtained from socioeconomic variables (e.g. population, unemployment, dwelling characteristics). To do this, ArcGis Network Analyst tool is used, which allows to calculate the optimal evacuation routes. The methodology proposed here is implemented in the region of Castilla y León (94,230 km2). Urban areas prone to flash flooding are identified taking into account the following requirements: i) city centers are crossed by rivers or streams with a longitudinal slope higher than 0.01 m m-1; ii) city centers are potentially affected by flash floods; and iii) city centers are affected by an area with low or exceptional probability

  8. Design of a nonscaling fixed field alternating gradient accelerator

    Directory of Open Access Journals (Sweden)

    D. Trbojevic

    2005-05-01

    Full Text Available We present a design of nonscaling fixed field alternating gradient accelerators (FFAG minimizing the dispersion action function H. The design is considered both analytically and via computer modeling. We present the basic principles of a nonscaling FFAG lattice and discuss optimization strategies so that one can accelerate over a broad range of momentum with reasonable apertures. Acceleration schemes for muons are discussed.

  9. Expert System Approach For Generating And Evaluating Engine Design Alternatives

    Science.gov (United States)

    Shen, Stewart N. T.; Chew, Meng-Sang; Issa, Ghassan F.

    1989-03-01

    Artificial intelligence is becoming an increasingly important subject of study for computer scientists, engineering designers, as well as professionals in other fields. Even though AI technology is a relatively new discipline, many of its concepts have already found practical applications. Expert systems, in particular, have made significant contributions to technologies in such fields as business, medicine, engineering design, chemistry, and particle physics. This paper describes an expert system developed to aid the mechanical designer with the preliminary design of variable-stroke internal-combustion engines. The expert system accomplished its task by generating and evaluating a large number of design alternatives represented in the form of graphs. Through the application of structural and design rules directly to the graphs, optimal and near optimal preliminary design configurations of engines are deduced.

  10. A Critical Review of Surveys Emphasizing on Routing in Wireless Sensor Networks-An Anatomization under General Survey Design Framework.

    Science.gov (United States)

    Rehan, Waqas; Fischer, Stefan; Rehan, Maaz

    2017-07-26

    A large number of routing-related surveys are published so far for Wireless Sensor Networks (WSNs) that exhibit either complete or partial emphasis on routing in WSNs. These surveys classify and discuss the relevant routing protocols published mainly in the fields of classical, energy efficient, secure, hierarchical, geographic, intelligent, Quality of Service (QoS)-based and multipath WSNs. However, to the best of our knowledge, no study is presented so far which may clearly categorize the routing-related survey literature for WSNs.To fill this gap, an effort is made in this paper for presenting an in-depth review of already published routing-related survey literature in WSNs. Our review initially proposes a generalized survey design model and afterwards analyzes the routing-related survey literature in the light of the devised General Survey Design Framework (GSDF) . Such an analysis describes the design soundness of the published routing-related surveys. Therefore, our review puts forth an original classification based on the frequency-of-survey-publication and taxonomizes the corresponding routing-related fields into high, medium and low focused areas of survey publication in WSNs. Furthermore, the surveys belonging to each main category are sub-categorized into various sub-classes and briefly discussed according to their design characteristics. On the one hand, this review is useful for beginners who may easily explore the already published routing-related survey literature in WSNs in a single document and investigate it by spending less effort. On the other hand, it is useful for expert researchers who may explore the trends and frequency of writing surveys in different areas of routing in WSNs. The experts may explore those areas of routing which are either neglected or least focused or lack in design soundness as per general survey design framework. In the end, insights and future research directions are outlined and a reasonable conclusion is put forth

  11. Hurricane Evacuation Routes

    Data.gov (United States)

    Department of Homeland Security — Hurricane Evacuation Routes in the United States A hurricane evacuation route is a designated route used to direct traffic inland in case of a hurricane threat. This...

  12. Alternate Design of ITER Cryostat Skirt Support System

    Science.gov (United States)

    Pandey, Manish Kumar; Jha, Saroj Kumar; Gupta, Girish Kumar; Bhattacharya, Avik; Jogi, Gaurav; Bhardwaj, Anil Kumar

    2017-04-01

    The skirt support of ITER cryostat is a support system which takes all the load of cryostat cylinder and dome during normal and operational condition. The present design of skirt support has full penetration weld joints at the bottom (shell to horizontal plate joint). To fulfil the requirements of tolerances and control the welding distortions, we have proposed to change the full penetration weld into fillet weld. A detail calculation is done to check the feasibility and structural impact due to proposed design. The calculations provide the size requirements of fillet weld. To verify the structural integrity during most severe load case, finite element analysis (FEA) has been done in line with ASME section VIII division 2 [1]. By FEA ‘Plastic Collapse’ and ‘Local Failure’ modes has been assessed. 5° sector of skirt clamp has been modelled in CATIA V5 R21 and used in FEA. Fillet weld at shell to horizontal plate joint has been modelled and symmetry boundary condition at ± 2.5° applied. ‘Elastic Plastic Analysis’ has been performed for the most severe loading case i.e. Category IV loading. The alternate design of Cryostat Skirt support system has been found safe by analysis against Plastic collapse and Local Failure Modes with load proportionality factor 2.3. Alternate design of Cryostat skirt support system has been done and validated by FEA. As per alternate design, the proposal of fillet weld has been implemented in manufacturing.

  13. Schema Design Alternatives for Multi-Granular Data Warehousing

    DEFF Research Database (Denmark)

    Iftikhar, Nadeem; Pedersen, Torben Bach

    2010-01-01

    Data warehousing is widely used in industry for reporting and analysis of huge volumes of data at different levels of detail. In general, data warehouses use standard dimensional schema designs to organize their data. However, current data warehousing schema designs fall short in their ability...... that the schema designs are intended to simply store data at the same single level of granularity. This paper on the other hand, presents several extended dimensional data warehousing schema design alternatives to store both detail and aggregated data at different levels of granularity. The paper presents three...... solutions to design the time dimension tables and four solutions to design the fact tables. Moreover, each of these solutions is evaluated in different combinations of the time dimension and the fact tables based on a real world farming case study....

  14. 40 CFR 60.4112 - Changing Hg designated representative and alternate Hg designated representative; changes in...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Changing Hg designated representative and alternate Hg designated representative; changes in owners and operators. 60.4112 Section 60.4112... Generating Units Hg Designated Representative for Hg Budget Sources § 60.4112 Changing Hg designated...

  15. Experimental assessment of level pool routing in preliminary design of floodplain storage.

    Science.gov (United States)

    De Martino, Giuseppe; De Paola, Francesco; Fontana, Nicola; Marini, Gustavo; Ranucci, Antonio

    2012-02-01

    Among control structures in flood management, floodplain storage represents one of the most effective measures, since it holds part of flood volume in a delimited area thus reducing the peak discharge. Sizing of floodplain storage, both on-stream and off-stream, is complex and several methodologies for preliminary design are available in literature, almost all assuming level pool reservoir routing, i.e. the water level in the floodplain is horizontal during the storage filling. Few studies examine the accuracy of that assumption. The present paper work reports an extensive experimental investigation to assess the reliability of level pool routing in the design of on-stream floodplain storages. The good agreement between numerical and experimental values during the filling phase confirmed the reliability of the hypothesis in the preliminary sizing of on-stream floodplain storage. In contrast, even significant differences can be shown during the floodplain draining, due to vegetation and bottom irregularities. Copyright © 2011 Elsevier B.V. All rights reserved.

  16. Variability in Criteria for Emergency Medical Services Routing of Acute Stroke Patients to Designated Stroke Center Hospitals.

    Science.gov (United States)

    Dimitrov, Nikolay; Koenig, William; Bosson, Nichole; Song, Sarah; Saver, Jeffrey L; Mack, William J; Sanossian, Nerses

    2015-09-01

    Comprehensive stroke systems of care include routing to the nearest designated stroke center hospital, bypassing non-designated hospitals. Routing protocols are implemented at the state or county level and vary in qualification criteria and determination of destination hospital. We surveyed all counties in the state of California for presence and characteristics of their prehospital stroke routing protocols. Each county's local emergency medical services agency (LEMSA) was queried for the presence of a stroke routing protocol. We reviewed these protocols for method of stroke identification and criteria for patient transport to a stroke center. Thirty-three LEMSAs serve 58 counties in California with populations ranging from 1,175 to nearly 10 million. Fifteen LEMSAs (45%) had stroke routing protocols, covering 23 counties (40%) and 68% of the state population. Counties with protocols had higher population density (1,500 vs. 140 persons per square mile). In the six counties without designated stroke centers, patients meeting criteria were transported out of county. Stroke identification in the field was achieved using the Cincinnati Prehospital Stroke Screen in 72%, Los Angeles Prehospital Stroke Screen in 7% and a county-specific protocol in 22%. California EMS prehospital acute stroke routing protocols cover 68% of the state population and vary in characteristics including activation by symptom onset time and destination facility features, reflecting matching of system design to local geographic resources.

  17. Environmental comparison of a railway bridge with alternative designs

    DEFF Research Database (Denmark)

    Du, Guangli; Karoumi, Raid

    2012-01-01

    Railway bridges are complex structures that remain for a long life span and consume large amount of material and energy throughout the life span. All of those lead to considerable resource depletion and environmental burdens. Life Cycle Assessment (LCA) has proved to be a comprehensive tool...... for quantifying and assessing the environmental impacts of the products through its whole life cycle. This paper presents a comparative case study between two alternative designs of Banafjäl Bridge: ballast track design and fixed slab track design. The methodology of LCA is utilized as a supporting tool....... The assessment considers the key environmental category of global warming potential from 'cradle to gate', which covers the material production and distribution process. The result shows that the fixed-slab design indicates a better environmental performance than the ballast track design....

  18. The Alternative Design Features for Safety Enhancement in Shutdown Operation

    International Nuclear Information System (INIS)

    Oh, Hae Cheol; Kim, Myung Ki; Chung, Bag Soon; Seo, Mi Ro

    2009-01-01

    PSA can be used to confirm that the new plant design is complied with the applicable safety goals, and to select among the alternate design options. A shutdown PSA provides insight for outage planning schedule, outage management practices, and design modifications. Considering the results of both LPSD PSA studies and operating experiences for low power and shutdown, the improvements can be proposed to reduce the high risk contribution. The improvements/enhancements during shutdown operation may be divided into categories such as hardware, administrative management, and operational procedure. This paper presents on an example how the risk related to an accidental situation can be reduced, focusing the hardware design changes for the newly designed NPPs

  19. Design, designer and designer’s liability in construction procurement routes

    OpenAIRE

    Akbiyikli, Rifat; Onur Ugur, Latif; Ateş, Ali; Polat, Hakan

    2016-01-01

    In construction projects, the question of who bears the risk and responsibility for the design of the project is often a source of dispute between the project owner, on the one hand, and the architect/engineer or the contractor/subcontractor(s), on the other hand. All parties to a construction project should ensure they have read and understood their design responsibilities pursuant to the terms of their contracts. Most importantly, parties should ensure that the contracts explicitly reflect ...

  20. Power-Aware Routing and Network Design with Bundled Links: Solutions and Analysis

    Directory of Open Access Journals (Sweden)

    Rosario G. Garroppo

    2013-01-01

    Full Text Available The paper deeply analyzes a novel network-wide power management problem, called Power-Aware Routing and Network Design with Bundled Links (PARND-BL, which is able to take into account both the relationship between the power consumption and the traffic throughput of the nodes and to power off both the chassis and even the single Physical Interface Card (PIC composing each link. The solutions of the PARND-BL model have been analyzed by taking into account different aspects associated with the actual applicability in real network scenarios: (i the time for obtaining the solution, (ii the deployed network topology and the resulting topology provided by the solution, (iii the power behavior of the network elements, (iv the traffic load, (v the QoS requirement, and (vi the number of paths to route each traffic demand. Among the most interesting and novel results, our analysis shows that the strategy of minimizing the number of powered-on network elements through the traffic consolidation does not always produce power savings, and the solution of this kind of problems, in some cases, can lead to spliting a single traffic demand into a high number of paths.

  1. Optimal design of mixed-media packet-switching networks - Routing and capacity assignment

    Science.gov (United States)

    Huynh, D.; Kuo, F. F.; Kobayashi, H.

    1977-01-01

    This paper considers a mixed-media packet-switched computer communication network which consists of a low-delay terrestrial store-and-forward subnet combined with a low-cost high-bandwidth satellite subnet. We show how to route traffic via ground and/or satellite links by means of static, deterministic procedures and assign capacities to channels subject to a given linear cost such that the network average delay is minimized. Two operational schemes for this network model are investigated: one is a scheme in which the satellite channel is used as a slotted ALOHA channel; the other is a new multiaccess scheme we propose in which whenever a channel collision occurs, retransmission of the involved packets will route through ground links to their destinations. The performance of both schemes is evaluated and compared in terms of cost and average packet delay tradeoffs for some examples. The results offer guidelines for the design and optimal utilization of mixed-media networks.

  2. Optimal Channel Width Adaptation, Logical Topology Design, and Routing in Wireless Mesh Networks

    Directory of Open Access Journals (Sweden)

    Li Li

    2009-01-01

    Full Text Available Radio frequency spectrum is a finite and scarce resource. How to efficiently use the spectrum resource is one of the fundamental issues for multi-radio multi-channel wireless mesh networks. However, past research efforts that attempt to exploit multiple channels always assume channels of fixed predetermined width, which prohibits the further effective use of the spectrum resource. In this paper, we address how to optimally adapt channel width to more efficiently utilize the spectrum in IEEE802.11-based multi-radio multi-channel mesh networks. We mathematically formulate the channel width adaptation, logical topology design, and routing as a joint mixed 0-1 integer linear optimization problem, and we also propose our heuristic assignment algorithm. Simulation results show that our method can significantly improve spectrum use efficiency and network performance.

  3. Design of a Multi-layer Lane-Level Map for Vehicle Route Planning

    Directory of Open Access Journals (Sweden)

    Liu Chaoran

    2017-01-01

    Full Text Available With the development of intelligent transportation system, there occurs further demand for high precision localization and route planning, and simultaneously the traditional road-level map fails to meet with this requirement, by which this paper is motivated. In this paper, t he three-layer lane-level map architecture for vehicle path guidance is established, and the mathematical models of road-level layer, intermediate layer and lane-level layer are designed considering efficiency and precision. The geometric model of the lane-level layer of the map is characterized by Cubic Hermite Spline for continuity. A method of generating the lane geometry with fixed and variable control points is proposed, which can effectively ensure the accuracy with limited num ber of control points. In experimental part, a multi-layer map of an intersection is built to validate the map model, and an example of a local map was generated with the lane-level geometry.

  4. An alternative LEU design for the FRM-II

    International Nuclear Information System (INIS)

    Hanan, N.A.; Mo, S.C.; Smith, R.S.; Matos, J.E.

    1996-01-01

    The Alternative LEU Design for the FRM-II proposed by the RERTR Program at Argonne National Laboratory (ANL) has a compact core consisting of a single fuel element that uses LEU silicide fuel with a uranium density of 4.5 g/cm 3 and has a power level of 32 MW. Both the HEU design by the Technical University of Munich (TUM) and the alternative LEU design by ANL have the same fuel lifetime (50 days) and the same neutron flux performance. LEU silicide fuel with 4.5 g/cm 3 has been thoroughly tested and is fully-qualified, licensable, and available now for use in a high flux reactor such as the FRM-II. The following issues raised by TUM were addressed in Ref. 1: qualification of HEU and LEU silicide fuels, gamma heating in the heavy water reflector, radiological consequences of larger fission product and plutonium inventories in the LEU core, and cost and schedule. The conclusions of these analyses are summarized below. This paper addresses three additional safety issues that were raised by TUM in Ref. 2: stability of the involute fuel plates, a hypothetical accident involving the configuration of the reflector, and a loss of primary coolant flow transient due to an interrupted power supply. Based on the excellent results for the Alternative LEU Design that were obtained in these analyses, the RERTR Program concludes that all of the major technical issues regarding use of LEU fuel instead of HEU fuel in the FRM-II have been successfully resolved and that it is definitely feasible to use LEU fuel in the FRM-II without compromising the safety or performance of the facility

  5. Alternative transmission routes in the malaria elimination era: an overview of transfusion-transmitted malaria in the Americas.

    Science.gov (United States)

    Alho, Regina M; Machado, Kim Vinícius Amaral; Val, Fernando F A; Fraiji, Nelson A; Alexandre, Marcia A A; Melo, Gisely C; Recht, Judith; Siqueira, André M; Monteiro, Wuelton M; Lacerda, Marcus V G

    2017-02-15

    Transfusion-transmitted (TT) malaria is an alternative infection route that has gained little attention from authorities, despite representing a life-threatening condition. There has been no systematic review of this health problem in American countries. The aim of this study was to describe the clinical and epidemiological characteristics of TT malaria in the Americas and identify factors associated with lethality based on the studies published in the literature. Potentially relevant papers in all languages were retrieved from MEDLINE and LILACS. Additional articles were obtained from reviews and original papers. Publications on screening of candidate blood donors and on surveillance of TT malaria cases were included. Odds ratios with respective 95% confidence intervals (95% CI) were calculated. Epidemiological characteristics of blood donors of TT malaria cases, including a pooled positivity of different tests for malaria diagnosis, were retrieved. A total of 63 publications regarding TT malaria from seven countries were included, from 1971 to 2016. A total of 422 cases of TT malaria were recorded. Most TT malaria cases were in females (62.0%) and 39.5% were in the ≥61 years-old age group. About half of all cases were from Mexico (50.7%), 40.3% from the United States of America (USA) and 6.6% from Brazil. Gyneco-obstetrical conditions (67.3%), surgical procedures (20.6%) and complications from neoplasias (6.1%) were the most common indications of transfusion. Packed red blood cells (RBCs) (50.7%) and whole blood (43.3%) were the blood products mostly associated with TT malaria. Cases were mostly caused by Plasmodium malariae (58.4%), followed by Plasmodium vivax (20.7%) and Plasmodium falciparum (17.9%). A total of 66.6% of cases were diagnosed by microscopy. Incubation period of 2-3 weeks was the most commonly observed (28.6%). Lethality was seen in 5.3% of cases and was associated with living in non-endemic countries, P. falciparum infection and concomitant

  6. Arizona Public Service - Alternative Fuel (Hydrogen) Pilot Plant Design Report

    Energy Technology Data Exchange (ETDEWEB)

    James E. Francfort

    2003-12-01

    Hydrogen has promise to be the fuel of the future. Its use as a chemical reagent and as a rocket propellant has grown to over eight million metric tons per year in the United States. Although use of hydrogen is abundant, it has not been used extensively as a transportation fuel. To assess the viability of hydrogen as a transportation fuel and the viability of producing hydrogen using off-peak electric energy, Pinnacle West Capital Corporation (PNW) and its electric utility subsidiary, Arizona Public Service (APS) designed, constructed, and operates a hydrogen and compressed natural gas fueling station—the APS Alternative Fuel Pilot Plant. This report summarizes the design of the APS Alternative Fuel Pilot Plant and presents lessons learned from its design and construction. Electric Transportation Applications prepared this report under contract to the U.S. Department of Energy’s Advanced Vehicle Testing Activity. The Idaho National Engineering and Environmental Laboratory manages these activities for the Advanced Vehicle Testing Activity.

  7. Human factors in design modifications: panel alternative stop in Almaraz

    International Nuclear Information System (INIS)

    Roman, Y.; Bote, J.

    2015-01-01

    Human Factors Engineering has acquired a crucial role in the development of any design modification (DM), where every aspect relative to any interaction with the human user has to be taken into account at any stage thereof. Considering this, during the last years, Almaraz Nuclear Powe Plants has developed a program of Human Factors Engineering in order to reach the internationally recognized standards or systematic collected on NUREG 0711 Human Factors Engineering Program Review Model (NRC). One of the most important projects of this program at Almaraz Nuclear Power Plant has been the implementation of the Alternative Stop Panel and their corresponding Transfer Panels. (Author)

  8. Neural and Hybrid Modeling: An Alternative Route to Efficiently Predict the Behavior of Biotechnological Processes Aimed at Biofuels Obtainment

    Directory of Open Access Journals (Sweden)

    Stefano Curcio

    2014-01-01

    Full Text Available The present paper was aimed at showing that advanced modeling techniques, based either on artificial neural networks or on hybrid systems, might efficiently predict the behavior of two biotechnological processes designed for the obtainment of second-generation biofuels from waste biomasses. In particular, the enzymatic transesterification of waste-oil glycerides, the key step for the obtainment of biodiesel, and the anaerobic digestion of agroindustry wastes to produce biogas were modeled. It was proved that the proposed modeling approaches provided very accurate predictions of systems behavior. Both neural network and hybrid modeling definitely represented a valid alternative to traditional theoretical models, especially when comprehensive knowledge of the metabolic pathways, of the true kinetic mechanisms, and of the transport phenomena involved in biotechnological processes was difficult to be achieved.

  9. Alternative bipolar plates design and manufacturing for PEM fuel cell

    International Nuclear Information System (INIS)

    Lee Chang Chuan; Norhamidi Muhamad; Jaafar Sahari

    2006-01-01

    Bipolar plates is one of the important components in fuel cell stack, it comprise up to 80% of the stack volume. Traditionally, these plates have been fabricated from graphite, owing to its chemical nobility, and high electrical and thermal conductivity; but these plates are brittle and relatively thick. Therefore increasing the stack volume and size. Alternatives to graphite are carbon-carbon composite, carbon-polymer composite and metal (aluminum, stainless steel, titanium and nickel based alloy). The use of coated and uncoated metal bipolar plates has received attention recently due to the simplicity of plate manufacturing. The thin nature of the metal substrate allows for smaller stack design with reduced weight. Lightweight coated metals as alternative to graphite plate is being developed. Beside the traditional method of machining and slurry molding, metal foam for bipolar plates fabrication seems to be a good alternative. The plates will be produced with titanium powder by Powder Metallurgy method using space holders technique to produce the meal foam flow-field. This work intends to facilitate the materials and manufacturing process requirements to produce cost effective foamed bipolar plates for fuel cell

  10. Design and Analysis of QoS Routing Framework integrated with OLSR protocol for Multimedia Traffic in Mobile Adhoc Networks

    Directory of Open Access Journals (Sweden)

    S. Soni

    2017-06-01

    Full Text Available MANETs (Mobile Ad-hoc Networks is the self organizing wireless structure of mobile hosts. Wireless media is used for communication in MANETs. Considering the developing requirements for multimedia and real-time traffic applications in real world, QoS (Quality-of-Service support is essential in MANETs. But most of the characteristics of MANETs make QoS support a difficult problem. It is challenging to support QoS routing in MANET due to dynamic behavior and mobility of the hosts. The OLSR (Optimized Link State Routing protocol can be efficiently used in MANETs to provide QoS routing because of its dynamic MPR (Multi Point Relay selection criteria and proactive nature. In this paper, a design of QoS routing framework integrated with OLSR protocol is proposed and also analyzed using network simulator. Proposed QoS framework combines a bandwidth estimation algorithm with explicit resource reservation, QoS routing and connection admission control (CAC. OLSR protocol is extended for QoS framework to solve performance issues related to node mobility using cross layer approach. Results after simulation conclude about efficiency of the proposed QoS routing framework.

  11. Routes for GMR-Sensor Design in Non-Destructive Testing

    Directory of Open Access Journals (Sweden)

    Andreas Schütze

    2012-09-01

    Full Text Available GMR sensors are widely used in many industrial segments such as information technology, automotive, automation and production, and safety applications. Each area requires an adaption of the sensor arrangement in terms of size adaption and alignment with respect to the field source involved. This paper deals with an analysis of geometric sensor parameters and the arrangement of GMR sensors providing a design roadmap for non-destructive testing (NDT applications. For this purpose we use an analytical model simulating the magnetic flux leakage (MFL distribution of surface breaking defects and investigate the flux leakage signal as a function of various sensor parameters. Our calculations show both the influence of sensor length and height and that when detecting the magnetic flux leakage of µm sized defects a gradiometer base line of 250 µm leads to a signal strength loss of less than 10% in comparison with a magnetometer response. To validate the simulation results we finally performed measurements with a GMR magnetometer sensor on a test plate with artificial µm-range cracks. The differences between simulation and measurement are below 6%. We report on the routes for a GMR gradiometer design as a basis for the fabrication of NDT-adapted sensor arrays. The results are also helpful for the use of GMR in other application when it comes to measure positions, lengths, angles or electrical currents.

  12. Total System Performance Assessment: Enhanced Design Alternative IV

    Energy Technology Data Exchange (ETDEWEB)

    P.D. Mattie

    1999-06-23

    The purpose of this calculation is to document total system performance assessment modeling of Enhanced Design Alternative (EDA) Feature IV. Total System Performance Assessment (TSPA) calculations for EDA IV are based on the TSPA-VA Base Case which has been modified with a quartz sand invert, quartz sand backfill, line loading and 21 PWR waste packages that have 2-cm thick titanium grade 7 corrosion resistant material (CRM) drip shields that are placed over a 30 cm thick carbon steel (A5 16) waste package with an integral filler material (CRWMS M&O 1999a & 1999b). This document details the changes and assumptions made to the VA reference Performance Assessment Model (CRWMS M&O 1998a) to incorporate the design changes detailed for EDA IV. The performance measure for this evaluation is the expected value dose-rate history at 20 km from the repository boundary.

  13. Creating An Alternative Design for Asita Corporate Identity

    Directory of Open Access Journals (Sweden)

    Michelle Elise

    2015-10-01

    Full Text Available The objective of the study is to find the solution to the problem outlined, which is to create an alternative design for corporate identity of ASITA. ASITA is a non-profit organization to foster tours and travel agencies in Indonesia. The writer conducted interview to the ASITA Jakarta Chapter, which was appointed to represent ASITA in providing the data needed by the writer. The writer interviewed the advisor of the organization, which had once served as chairperson of ASITA. The result of the research is new corporate identity system of ASITA based on a concept that ASITA as an organization, serves as a compass that guides and assists in every direction. The writer found that corporate identity is an important element to define an organization as well as giving impact on its first impression. To create good corporate identity, several things such as elements of design, color, typography, etc need to be put into attention. 

  14. Total System Performance Assessment: Enhanced Design Alternative V

    International Nuclear Information System (INIS)

    N. Erb; S. Miller; V. Vallikat

    1999-01-01

    This calculation documents the total system performance assessment modeling of Enhanced Design Analysis (EDA) V. EDA V is based on the TSPA-VA base design which has been modified with higher thermal loading, a quartz sand invert, and line loading with 21 PWR waste packages that have 2-cm thick titanium grade 7 corrosion resistance material (CRM) drip shields placed over dual-layer waste packages composed of 'inside out' VA reference material (CRWMS M and O 1999a). This document details the changes and assumptions made to the VA reference Performance Assessment Model (CRWMS M and O 1998a) to incorporate the design changes detailed for EDA V. The performance measure for this evaluation is expected value dose-rate history. Time histories of dose rate are presented for EDA V and a Defense in Depth (DID) analysis base on EDA V. Additional details concerning the Enhanced Design Alternative II are provided in the 'LADS 3-12 Requests' interoffice correspondence (CRWMS M and O 1999a)

  15. Quantitative design space exploration of routing-switches for Network-on-Chip

    Directory of Open Access Journals (Sweden)

    M. C. Neuenhahn

    2008-05-01

    Full Text Available Future Systems-on-Chip (SoC will consist of many embedded functional units like e.g. embedded processor cores, memories or FPGA like structures. These SoCs will have huge communication demands, which can not be fulfilled by bus-based communication systems. Possible solutions to this problem are so called Networks-on-Chip (NoC.

    These NoCs basically consist of network-interfaces which integrate functional units into the NoC and routing-switches which connect the network-interfaces. Here, VLSI-based routing-switch implementations are presented. The characteristics of these NoCs like performance and costs (e.g. silicon area respectively logic elements, power dissipation depend on a variety of parameters. As a routing-switch is a key component of a NoC, the costs and performance of routing-switches are compared for different parameter combinations. Evaluated parameters are for example data word length, architecture of the routing-switch (parallel vs. centralized implementation and routing-algorithm.

    The performance and costs of routing-switches were evaluated using an FPGA-based NoC-emulator. In addition different routing-switches were implemented using a 90 nm standard-cell library to determine the maximum clock frequency, power-dissipation and area of a VLSI-implementation. The power consumption was determined by simulating the extracted layout of the routing-switches. Finally, these results are benchmarked to other routing-switch implementations like Aetheral and xpipes.

  16. Screening of one-well hydraulic barrier design alternatives.

    Science.gov (United States)

    Rubin, Hillel; Shoemaker, Christine A; Köngeter, Jürgen

    2008-01-01

    Abstract This study develops a robust method for screening one-well hydraulic barrier design alternatives that can be easily computed without a numerical simulation model. The paper outlines the general method and shows its implementation with hydraulic barriers using a single pumping well. For such barriers, the method is easily computable with spreadsheets and/or charts depicted within the paper and posted online. The method applies the potential flow theory, which leads to using a curvilinear coordinate system for all types of calculations. For contaminant transport calculations, the method applies the boundary layer theory. For calculations of aquifer remediation, the method refers to bulk characteristics of the domain. As an example, the method has been applied to calculate the possible containment of a wide part of the coastal plain aquifer in Israel, which is contaminated by entrapped kerosene (a light nonaqueous phase liquid).

  17. Incorporating alternative design clinical trials in network meta-analyses

    Directory of Open Access Journals (Sweden)

    Thorlund K

    2014-12-01

    Full Text Available Kristian Thorlund,1–3 Eric Druyts,1,4 Kabirraaj Toor,1,5 Jeroen P Jansen,1,6 Edward J Mills1,3 1Redwood Outcomes, Vancouver, BC, 2Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada; 3Stanford Prevention Research Center, Stanford University, Stanford, CA, USA; 4Department of Medicine, Faculty of Medicine, 5School of Population and Public Health, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada; 6Department of Public Health and Community Medicine, Tufts University, Boston, MA, USA Introduction: Network meta-analysis (NMA is an extension of conventional pairwise meta-analysis that allows for simultaneous comparison of multiple interventions. Well-established drug class efficacies have become commonplace in many disease areas. Thus, for reasons of ethics and equipoise, it is not practical to randomize patients to placebo or older drug classes. Unique randomized clinical trial designs are an attempt to navigate these obstacles. These alternative designs, however, pose challenges when attempting to incorporate data into NMAs. Using ulcerative colitis as an example, we illustrate an example of a method where data provided by these trials are used to populate treatment networks. Methods: We present the methods used to convert data from the PURSUIT trial into a typical parallel design for inclusion in our NMA. Data were required for three arms: golimumab 100 mg; golimumab 50 mg; and placebo. Golimumab 100 mg induction data were available; however, data regarding those individuals who were nonresponders at induction and those who were responders at maintenance were not reported, and as such, had to be imputed using data from the rerandomization phase. Golimumab 50 mg data regarding responses at week 6 were not available. Existing relationships between the available components were used to impute the expected proportions in this missing subpopulation. Data for placebo maintenance

  18. Towards designing energy-efficient routing protocol for wireless mesh networks

    CSIR Research Space (South Africa)

    Dludla, AG

    2009-08-01

    Full Text Available Different studies have proposed number of routing protocols to overcome data transmission challenges. Very few of these protocols consider node energy. In this study, the state of art work from various studies is reviewed and compared based...

  19. Design and implementation of a delay-optimized universal programmable routing circuit for FPGAs

    International Nuclear Information System (INIS)

    Wu Fang; Zhang Huowen; Lai Jinmei; Wang Yuan; Chen Liguang; Duan Lei; Tong Jiarong

    2009-01-01

    This paper presents a universal field programmable gate array (FPGA) programmable routing circuit, focusing primarily on a delay optimization. Under the precondition of the routing resource's flexibility and routability, the number of programmable interconnect points (PIP) is reduced, and a multiplexer (MUX) plus a BUFFER structure is adopted as the programmable switch. Also, the method of offset lines and the method of complementary hanged end-lines are applied to the TILE routing circuit and the I/O routing circuit, respectively. All of the above features ensure that the whole FPGA chip is highly repeatable, and the signal delay is uniform and predictable over the total chip. Meanwhile, the BUFFER driver is optimized to decrease the signal delay by up to 5%. The proposed routing circuit is applied to the Fudan programmable device (FDP) FPGA, which has been taped out with an SMIC 0.18-μm logic 1P6M process. The test result shows that the programmable routing resource works correctly, and the signal delay over the chip is highly uniform and predictable.

  20. Nasal route for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA: An alternative modality in difficult oral bronchoscope insertion

    Directory of Open Access Journals (Sweden)

    Saurabh Mittal

    2017-01-01

    Full Text Available Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA is usually performed under moderate sedation through the oral approach. Oral insertion is performed owing to the larger size of the EBUS bronchoscope as well as the delicate and rigid distal end with an integrated ultrasound transducer assembly. Nasal route for EBUS scope insertion has been described as a feasible alternative. We herein report a patient wherein inability to introduce the EBUS bronchoscope through the mouth necessitated nasal insertion of the bronchoscope to successfully perform EBUS-TBNA. We discuss the relevant issues comparing the nasal and oral introduction of the EBUS bronchoscope.

  1. On Energy-Efficient Hierarchical Cross-Layer Design: Joint Power Control and Routing for Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Poor HVincent

    2007-01-01

    Full Text Available A hierarchical cross-layer design approach is proposed to increase energy efficiency in ad hoc networks through joint adaptation of nodes' transmitting powers and route selection. The design maintains the advantages of the classic OSI model, while accounting for the cross-coupling between layers, through information sharing. The proposed joint power control and routing algorithm is shown to increase significantly the overall energy efficiency of the network, at the expense of a moderate increase in complexity. Performance enhancement of the joint design using multiuser detection is also investigated, and it is shown that the use of multiuser detection can increase the capacity of the ad hoc network significantly for a given level of energy consumption.

  2. On Energy-Efficient Hierarchical Cross-Layer Design: Joint Power Control and Routing for Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Cristina Comaniciu

    2007-03-01

    Full Text Available A hierarchical cross-layer design approach is proposed to increase energy efficiency in ad hoc networks through joint adaptation of nodes' transmitting powers and route selection. The design maintains the advantages of the classic OSI model, while accounting for the cross-coupling between layers, through information sharing. The proposed joint power control and routing algorithm is shown to increase significantly the overall energy efficiency of the network, at the expense of a moderate increase in complexity. Performance enhancement of the joint design using multiuser detection is also investigated, and it is shown that the use of multiuser detection can increase the capacity of the ad hoc network significantly for a given level of energy consumption.

  3. Design and Analysis of A Beacon-Less Routing Protocol for Large Volume Content Dissemination in Vehicular Ad Hoc Networks.

    Science.gov (United States)

    Hu, Miao; Zhong, Zhangdui; Ni, Minming; Baiocchi, Andrea

    2016-11-01

    Large volume content dissemination is pursued by the growing number of high quality applications for Vehicular Ad hoc NETworks(VANETs), e.g., the live road surveillance service and the video-based overtaking assistant service. For the highly dynamical vehicular network topology, beacon-less routing protocols have been proven to be efficient in achieving a balance between the system performance and the control overhead. However, to the authors' best knowledge, the routing design for large volume content has not been well considered in the previous work, which will introduce new challenges, e.g., the enhanced connectivity requirement for a radio link. In this paper, a link Lifetime-aware Beacon-less Routing Protocol (LBRP) is designed for large volume content delivery in VANETs. Each vehicle makes the forwarding decision based on the message header information and its current state, including the speed and position information. A semi-Markov process analytical model is proposed to evaluate the expected delay in constructing one routing path for LBRP. Simulations show that the proposed LBRP scheme outperforms the traditional dissemination protocols in providing a low end-to-end delay. The analytical model is shown to exhibit a good match on the delay estimation with Monte Carlo simulations, as well.

  4. NASA Alternative Orion Small Cell Battery Design Support

    Science.gov (United States)

    Haynes, Chuck

    2016-01-01

    and analysis were completed and reviewed for endorsement by NASA Engineering and Safety Center team members. All Key Test Objectives were met and the small cell design alternative was demonstrated and selected to be a feasible drop in replacement for the MPCV Orion CM Battery for EM2 mission.

  5. Comparison of the Intraperitoneal, Retroorbital and per Oral Routes for F 18 FDG Administration as Effective Alternatives to Intravenous Administration in Mouse Tumor Models Using Small Animal PET/CT Studies

    International Nuclear Information System (INIS)

    Kim, Chulhan; Kim, In Hye; Kim, Seo il; Kim, Young Sang; Kang, Se Hun; Moon, Seung Hwan; Kim, Tae Sung; Kim, Seok ki

    2011-01-01

    We compared alternative routes for 18F fluorodeoxyglucose (FDG) administration, such as the retroorbital (RO), intraperitoneal (IP) and per oral (PO) routes, with the intravenous (IV) route in normal tissues and tumors of mice. CRL 1642 (ATCC, Lewis lung carcinoma) cells were inoculated in female BALB/c nu/nu mice 6 to 10 weeks old. When the tumor grew to about 9mm in diameter, positron emission tomography (PET) scans were performed after FDG administration via the RO, IP, PO or IV route. Additional serial PET scans were performed using the RO, IV or IP route alternatively from 5 to 29 days after the tumor cell injection. There was no significant difference in the FDG uptake in normal tissues at 60 min after FDG administration via RO, IP and IV routes. PO administration, however, showed delayed distribution and unwanted high gastrointestinal uptake. Tumoral uptake of FDG showed a similar temporal pattern and increased until 60 min after FDG administration in the RO, IP and IV injection groups. In the PO administration group, tumoral uptake was delayed and reduced. There was no statistical difference among the RO, IP and IV administration groups for additional serial PET scans. RO administration is an effective alternative route to IV administration for mouse FDG PET scans using normal mice and tumor models. In addition, IP administration can be a practical alternative in the late phase, although the initial uptake is lower than those in the IV and RO groups.

  6. "Application of Box-Behnken design for optimization and development of quetiapine fumarate loaded chitosan nanoparticles for brain delivery via intranasal route* ".

    Science.gov (United States)

    Shah, Brijesh; Khunt, Dignesh; Misra, Manju; Padh, Harish

    2016-08-01

    The objective of the present investigation was to optimize and develop quetiapine fumarate (QF) loaded chitosan nanoparticles (QF-NP) by ionic gelation method using Box-Behnken design. Three independent variables viz., X1-Concentration of chitosan, X2-Concentration of sodium tripolyphosphate and X3-Volume of sodium tripolyphosphate were taken to investigate their effect on dependent variables (Y1-Size, Y2-PDI and Y3-%EE). Optimized formula of QF-NP was selected from the design space which was further evaluated for physicochemical, morphological, solid state characterization, nasal diffusion and in-vivo distribution for brain targeting following non-invasive intranasal administration. The average particle size, PDI, %EE and nasal diffusion were found to be 131.08±7.45nm, 0.252±0.064, 89.93±3.85% and 65.24±5.26% respectively. Neither toxicity nor structural damage on nasal mucosa was observed upon histopathological examination. Significantly higher brain/blood ratio and 2 folds higher nasal bioavailability in brain with QF-NP in comparison to drug solution following intranasal administration revealed preferential nose to brain transport bypassing blood-brain barrier and prolonged retention of QF at site of action suggesting superiority of chitosan as permeability enhancer. Overall, the above finding shows promising results in the area of developing non-invasive intranasal route as an alternative to oral route for brain delivery. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Design and economic analysis of a macroalgae-to-butanol process via a thermochemical route

    International Nuclear Information System (INIS)

    Okoli, Chinedu O.; Adams, Thomas A.; Brigljević, Boris; Liu, Jay J.

    2016-01-01

    Highlights: • Novel macroalgae-to-butanol plants are designed and assessed for U.S. and S. Korea. • The lowest MBSP of 1.97 $/L was obtained for the S. Korean natural gas import plant. • S. Korean plant with no fossil utilities had lowest CO 2 avoided cost of 620 $/tCO 2 e. • Macroalgae-to-butanol plants CO 2 avoided costs are competitive with other biofuels. • CO 2 avoided costs of assessed plants are most sensitive to changes in gasoline price. - Abstract: In this work, a first of its kind assessment of butanol production from macroalgae through a thermochemical route is carried out. Different process configurations were designed and simulated in Aspen Plus to quantify their mass and energy balances. Furthermore, economic and environmental metrics such as the minimum butanol selling price (MBSP), and cost of CO 2 equivalent emissions (CO 2 e) avoided were used to assess the potential of the different configurations under different market scenarios, with comparisons carried out amongst the configurations as well as against standard literature references of similar processes. Finally, a sensitivity analysis was used to assess the impact that changes in key parameters have on the considered metrics. The results show that configurations which import natural gas and electricity as utility sources alongside the macroalgae feedstock offer the lowest MBSP, however they do poorly when cost of CO 2 e avoided is considered. On the other hand, the configurations which utilize only macroalgae offer the best potential for cost of CO 2 e avoided but have the poorest values for MBSP. In addition, the cost of CO 2 e avoided obtained for the best configurations are in line with literature references. However, the MBSP values are higher than literature references for butanol derived from cellulosic feedstock primarily due to the high ash content in seaweed. The sensitivity analyses results show that changes in gasoline prices have a very significant effect on the plant

  8. The influence of globalization on medical regulation: a descriptive analysis of international medical graduates registered through alternative licensure routes in Ontario

    Directory of Open Access Journals (Sweden)

    Wendy Yen

    2016-12-01

    Full Text Available The increasing globalization of the medical profession has influenced health policy, health human resource planning, and medical regulation in Canada. Since the early 2000s, numerous policy initiatives have been created to facilitate the entry of international medical graduates (IMGs into the Canadian workforce. In Ontario, the College of Physicians and Surgeons of Ontario (CPSO developed alternative licensure routes to increase the ability of qualified IMGs to obtain licenses to practice. The current study provides demographic and descriptive information about the IMGs registered through the CPSO’s alternative licensure routes between 2000 and 2012. An analysis of the characteristics and career trajectories of all IMGs practicing in the province sheds light on broader globalization trends and raises questions about the future of health human resource planning in Canada. As the medical profession becomes increasingly globalized, health policy and regulation will continue to be influenced by trends in international migration, concerns about global health equity, and the shifting demographics of the Canadian physician workforce. Implications for future policy development in the complex landscape of medical education and practice are discussed.

  9. The influence of globalization on medical regulation: a descriptive analysis of international medical graduates registered through alternative licensure routes in Ontario.

    Science.gov (United States)

    Yen, Wendy; Hodwitz, Kathryn; Thakkar, Niels; Martimianakis, Maria Athina Tina; Faulkner, Dan

    2016-12-01

    The increasing globalization of the medical profession has influenced health policy, health human resource planning, and medical regulation in Canada. Since the early 2000s, numerous policy initiatives have been created to facilitate the entry of international medical graduates (IMGs) into the Canadian workforce. In Ontario, the College of Physicians and Surgeons of Ontario (CPSO) developed alternative licensure routes to increase the ability of qualified IMGs to obtain licenses to practice. The current study provides demographic and descriptive information about the IMGs registered through the CPSO's alternative licensure routes between 2000 and 2012. An analysis of the characteristics and career trajectories of all IMGs practicing in the province sheds light on broader globalization trends and raises questions about the future of health human resource planning in Canada. As the medical profession becomes increasingly globalized, health policy and regulation will continue to be influenced by trends in international migration, concerns about global health equity, and the shifting demographics of the Canadian physician workforce. Implications for future policy development in the complex landscape of medical education and practice are discussed.

  10. Alternative designs for petroleum product storage tanks for groundwater protection.

    Science.gov (United States)

    Oke Adeleke, Samson

    In developing countries, there are numerous occurrences of petroleum product spillage in groundwater. The current practice of burying storage tanks beneath the surface without adequate safety devices facilitates this phenomenon. Underground tanks rust and leak, and spilled petroleum products migrate downward. The movement of the oil in the soil depends on its viscosity and quantity, the permeability of the soil/rock, and the presence of fractures within the rock. The oil spreads laterally in the form of a thin pancake due to its lower specific gravity, and soluble components dissolve in water. The pollution plume of petroleum products and dissolved phases moves in the direction of groundwater flow in the aquifer within the pores of soil and sediments or along fractures in basement complex areas. Most communities reply heavily on groundwater for potable and industrial supplies. However, the sustainability of this resource is under threat in areas where there are filling stations as a result of significant groundwater contamination from petroleum product spillage. Drinking water becomes unpalatable when it contains petroleum products in low concentrations, and small quantities may contaminate large volumes of water. Considering the losses incurred from spillage, the cost of cleaning the aquifer, and the fact that total cleansing and attenuation is impossible, the need to prevent spillage and if it happens to prevent it from getting into the groundwater system is of paramount importance. This paper proposes alternative design procedures with a view to achieving these objectives.

  11. The study, design and simulation of a free piston Stirling engine linear alternatorThe study, design and simulation of a free piston Stirling engine linear alternator

    Directory of Open Access Journals (Sweden)

    Teodora Susana Oros

    2014-12-01

    Full Text Available This paper presents a study, design and simulation of a Free Piston Stirling Engine Linear Alternator. There are presented the main steps of the magnetic and electric calculations for a permanent magnet linear alternator of fixed coil and moving magnets type. Finally, a detailed thermal, mechanical and electrical model for a Stirling engine linear alternator have been made in SIMULINK simulation program. The linear alternator simulation model uses a controllable DC voltage which simulates the linear alternator combined with a rectifier, a variable load and a DC-DC converter, which compensates for the variable nature of Stirling engine operation, and ensures a constant voltage output regardless of the load.

  12. Route Design Model of Feeder Bus Service for Urban Rail Transit Stations

    Directory of Open Access Journals (Sweden)

    Zhenjun Zhu

    2017-01-01

    Full Text Available As an important part of urban public transportation systems, the feeder bus fills a service gap left by rail transit, effectively extending the range of rail transit’s service and solving the problem of short-distance travel and interchanges. By defining the potential demand of feeder bus services and considering its relationship with the traffic demands of corresponding staging areas, the distance between road and rail transit, and the repetition factor of road bus lines, this paper established a potential demand model of roads by opening feeder bus services and applying a logit model for passenger flow distribution. Based on a circular route model, a route starting and ending at urban rail transit stations was generated, and a genetic algorithm was then applied to solve it. The Wei-Fang community of Shanghai was selected as the test area. Per the model and algorithm, the feeder route length was conformed to a functional orientation of short-distance travel and the feeder service of a feeder bus; the route mostly covered where conventional bus lines were fewer, which is a finding that is in agreement with the actual situation; the feasibility of the model and algorithm was verified.

  13. Analysis of application of alternative drive systems for international heavy-duty transport on Wroclaw-Dresden-Prague routes

    Science.gov (United States)

    Skrętowicz, Maria; Sroka, Zbigniew

    2017-11-01

    The depletion of the fossil fuels resources, significant increase of the air pollution caused by the use of internal combustion engines, and emission of carbon dioxide which is responsible for the greenhouse effect escalates the development of vehicle's alternative drive systems. Generally, the emphasis is given to the alternative fuels (natural gas CNG, mixture of propane-butane gases LPG, hydrogen, alcohol fuels, biofuels) and hybrid or electric vehicles. Roads between large industrial and commercial centres, i.e. Wroclaw - Dresden - Prague, are used mainly by heavy-duty vehicles. Consequently, the contribution of the road transport to the ecological threat in this realm is significant. The objectives of this research were the assessment of the traffic volume and emission rate of exhaust gases caused by heavy-duty vehicles on the analysed roads and evaluation of the possibility of using existing and alternative drive systems in vehicles driving on the roads in the analysed region.

  14. RIP INPUT TABLES FROM WAPDEG FOR LA DESIGN SELECTION: ENHANCED DESIGN ALTERNATIVE V

    International Nuclear Information System (INIS)

    K. Mon

    1999-01-01

    The purpose of this calculation is to document (1) the Waste Package Degradation (WAPDEG) version 3.09 (CRWMS M and O 1998b, Software Routine Report for WAPDEG (Version 3.09)) simulations used to analyze degradation and failure of 2-cm thick titanium grade 7 corrosion resistant material (CRM) drip shields (that are placed over waste packages composed of a 2-cm thick Alloy 22 corrosion resistant material (CRM) as the outer barrier and an unspecified material to provide structural support as the inner barrier) as well as degradation and failure of the waste packages themselves, and (2) post-processing of these results into tables of drip shield/waste package degradation time histories suitable for use as input into the Integrated Probabilistic Simulator for Environmental Systems (RIP) version 5.19.01 (Golder Associates 1998) computer code. Performance credit of the inner barrier material is not taken in this calculation. This calculation supports Performance Assessment analysis of the License Application Design Selection (LADS) Enhanced Design Alternative V. Additional details concerning the Enhanced Design Alternative V are provided in a Design Input Request (CRWMS M and O 1999e, Design Input Request for LADS Phase II EDA Evaluations, Item 3)

  15. Bus Route Design with a Bayesian Network Analysis of Bus Service Revenues

    Directory of Open Access Journals (Sweden)

    Yi Liu

    2018-01-01

    Full Text Available A Bayesian network is used to estimate revenues of bus services in consideration of the effect of bus travel demands, passenger transport distances, and so on. In this research, the area X in Beijing has been selected as the study area because of its relatively high bus travel demand and, on the contrary, unsatisfactory bus services. It is suggested that the proposed Bayesian network approach is able to rationally predict the probabilities of different revenues of various route services, from the perspectives of both satisfying passenger demand and decreasing bus operation cost. This way, the existing bus routes in the studied area can be optimized for their most probable high revenues.

  16. Process of establishing design requirements and selecting alternative configurations for conceptual design of a VLA

    Directory of Open Access Journals (Sweden)

    Bo-Young Bae

    2017-04-01

    Full Text Available In this study, a process for establishing design requirements and selecting alternative configurations for the conceptual phase of aircraft design has been proposed. The proposed process uses system-engineering-based requirement-analysis techniques such as objective tree, analytic hierarchy process, and quality function deployment to establish logical and quantitative standards. Moreover, in order to perform a logical selection of alternative aircraft configurations, it uses advanced decision-making methods such as morphological matrix and technique for order preference by similarity to the ideal solution. In addition, a preliminary sizing tool has been developed to check the feasibility of the established performance requirements and to evaluate the flight performance of the selected configurations. The present process has been applied for a two-seater very light aircraft (VLA, resulting in a set of tentative design requirements and two families of VLA configurations: a high-wing configuration and a low-wing configuration. The resulting set of design requirements consists of three categories: customer requirements, certification requirements, and performance requirements. The performance requirements include two mission requirements for the flight range and the endurance by reflecting the customer requirements. The flight performances of the two configuration families were evaluated using the sizing tool developed and the low-wing configuration with conventional tails was selected as the best baseline configuration for the VLA.

  17. Cost-benefit analysis of alternative fuels and motive designs.

    Science.gov (United States)

    2013-04-01

    This project was funded by the Federal Railroad Administration to better understand the potential cost and benefits of using alternative fuels for U.S. freight and passenger locomotive operations. The framework for a decision model was developed by T...

  18. Bus Route Design with a Bayesian Network Analysis of Bus Service Revenues

    OpenAIRE

    Liu, Yi; Jia, Yuanhua; Feng, Xuesong; Wu, Jiang

    2018-01-01

    A Bayesian network is used to estimate revenues of bus services in consideration of the effect of bus travel demands, passenger transport distances, and so on. In this research, the area X in Beijing has been selected as the study area because of its relatively high bus travel demand and, on the contrary, unsatisfactory bus services. It is suggested that the proposed Bayesian network approach is able to rationally predict the probabilities of different revenues of various route services, from...

  19. Using sequence data to identify alternative routes and risk of infection: a case-study of campylobacter in Scotland

    Directory of Open Access Journals (Sweden)

    Bessell Paul R

    2012-04-01

    Full Text Available Abstract Background Genetic typing data are a potentially powerful resource for determining how infection is acquired. In this paper MLST typing was used to distinguish the routes and risks of infection of humans with Campylobacter jejuni from poultry and ruminant sources Methods C. jejuni samples from animal and environmental sources and from reported human cases confirmed between June 2005 and September 2006 were typed using MLST. The STRUCTURE software was used to assign the specific sequence types of the sporadic human cases to a particular source. We then used mixed case-case logistic regression analysis to compare the risk factors for being infected with C. jejuni from different sources. Results A total of 1,599 (46.3% cases were assigned to poultry, 1,070 (31.0% to ruminant and 67 (1.9% to wild bird sources; the remaining 715 (20.7% did not have a source that could be assigned with a probability of greater than 0.95. Compared to ruminant sources, cases attributed to poultry sources were typically among adults (odds ratio (OR = 1.497, 95% confidence intervals (CIs = 1.211, 1.852, not among males (OR = 0.834, 95% CIs = 0.712, 0.977, in areas with population density of greater than 500 people/km2 (OR = 1.213, 95% CIs = 1.030, 1.431, reported in the winter (OR = 1.272, 95% CIs = 1.067, 1.517 and had undertaken recent overseas travel (OR = 1.618, 95% CIs = 1.056, 2.481. The poultry assigned strains had a similar epidemiology to the unassigned strains, with the exception of a significantly higher likelihood of reporting overseas travel in unassigned strains. Conclusions Rather than estimate relative risks for acquiring infection, our analyses show that individuals acquire C. jejuni infection from different sources have different associated risk factors. By enhancing our ability to identify at-risk groups and the times at which these groups are likely to be at risk, this work allows public health messages to be targeted more effectively. The

  20. Efficient hydrogenation of organic carbonates, carbamates and formates indicates alternative routes to methanol based on CO2 and CO.

    Science.gov (United States)

    Balaraman, Ekambaram; Gunanathan, Chidambaram; Zhang, Jing; Shimon, Linda J W; Milstein, David

    2011-07-22

    Catalytic hydrogenation of organic carbonates, carbamates and formates is of significant interest both conceptually and practically, because these compounds can be produced from CO2 and CO, and their mild hydrogenation can provide alternative, mild approaches to the indirect hydrogenation of CO2 and CO to methanol, an important fuel and synthetic building block. Here, we report for the first time catalytic hydrogenation of organic carbonates to alcohols, and carbamates to alcohols and amines. Unprecedented homogeneously catalysed hydrogenation of organic formates to methanol has also been accomplished. The reactions are efficiently catalysed by dearomatized PNN Ru(II) pincer complexes derived from pyridine- and bipyridine-based tridentate ligands. These atom-economical reactions proceed under neutral, homogeneous conditions, at mild temperatures and under mild hydrogen pressures, and can operate in the absence of solvent with no generation of waste, representing the ultimate 'green' reactions. A possible mechanism involves metal-ligand cooperation by aromatization-dearomatization of the heteroaromatic pincer core.

  1. An integrated location inventory routing model in supply chain network designing under uncertainty

    Directory of Open Access Journals (Sweden)

    Hojat Angazi

    2016-09-01

    Full Text Available In this study an integrated model is proposed for the location inventory routing problem under uncertainty. This problem involves determining the location of distribution centers (DCs in a three echelon supply chain. The DCs receive orders from the customer and according to a continuous review inventory replenishment policy place orders to the supplier. The products are directly shipped from the supplier to the DCs. The vehicles start from the DCs to fulfill the demands of the customers. Determining the routing of the vehicles is one of the decisions involved in this problem. The demands of customers are stochastically distributed and the capacity of DCs are limited. If one of the DCs undergo a disruption and is unable to fulfill the demands of the customers, shortage may occur. Moreover in the proposed model the shortage is considered as partial backlogging. This means that if shortage occurs, some of the orders result in lost sales and other orders are fulfilled in the next period. In order to optimally solve the proposed model a nonlinear integer programming (INLP model is developed. However, since the problem is NP-hard, the mathematical formulation cannot be efficiently solved for large sized instances of the problem. Therefore an outer approximation method is developed to solve the problem more efficiently. The computational results show the efficiency of the proposed method.

  2. Values-led Participatory Design as a pursuit of meaningful alternatives

    DEFF Research Database (Denmark)

    Leong, Tuck Wah; Iversen, Ole Sejer

    2015-01-01

    Participatory Design (PD) is inherently concerned with inquiring into and supporting human values when designing IT. We argue that a PD approach that is led by a focus upon participants' values can allow participants to discover meaningful alternatives -- alternative uses and alternative...... conceptualizations for IT that are particularly meaningful to them. However, how PD works with values in the design process has not been made explicit. In this paper, we aim to (i) explicate this values-led PD approach, (ii) illustrate how this approach can lead to outcomes that are meaningful alternatives, and (iii...

  3. Efficient hydrogenation of organic carbonates, carbamates and formates indicates alternative routes to methanol based on CO2 and CO

    Science.gov (United States)

    Balaraman, Ekambaram; Gunanathan, Chidambaram; Zhang, Jing; Shimon, Linda J. W.; Milstein, David

    2011-08-01

    Catalytic hydrogenation of organic carbonates, carbamates and formates is of significant interest both conceptually and practically, because these compounds can be produced from CO2 and CO, and their mild hydrogenation can provide alternative, mild approaches to the indirect hydrogenation of CO2 and CO to methanol, an important fuel and synthetic building block. Here, we report for the first time catalytic hydrogenation of organic carbonates to alcohols, and carbamates to alcohols and amines. Unprecedented homogeneously catalysed hydrogenation of organic formates to methanol has also been accomplished. The reactions are efficiently catalysed by dearomatized PNN Ru(II) pincer complexes derived from pyridine- and bipyridine-based tridentate ligands. These atom-economical reactions proceed under neutral, homogeneous conditions, at mild temperatures and under mild hydrogen pressures, and can operate in the absence of solvent with no generation of waste, representing the ultimate ‘green’ reactions. A possible mechanism involves metal-ligand cooperation by aromatization-dearomatization of the heteroaromatic pincer core.

  4. Bicomponent Block Copolymers Derived from One or More Random Copolymers as an Alternative Route to Controllable Phase Behavior

    Energy Technology Data Exchange (ETDEWEB)

    Ashraf, Arman R. [Corporate Research and Development, The Procter and Gamble Company, Cincinnati OH 45224 USA; Ryan, Justin J. [Department of Materials Science and Engineering, North Carolina State University, Raleigh NC 27695 USA; Satkowski, Michael M. [Corporate Research and Development, The Procter and Gamble Company, Cincinnati OH 45224 USA; Lee, Byeongdu [Advanced Photon Source, Argonne National Laboratory, Argonne IL 60439 USA; Smith, Steven D. [Corporate Research and Development, The Procter and Gamble Company, Cincinnati OH 45224 USA; Spontak, Richard J. [Department of Materials Science and Engineering, North Carolina State University, Raleigh NC 27695 USA; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh NC 27695 USA

    2017-06-29

    Block copolymers have been extensively studied due to their ability to spontaneously self-organize into a wide variety of morphologies that are valuable in energy-, medical- and conservation-related (nano)technologies. While the phase behavior of bicomponent diblock and triblock copolymers is conventionally governed by temperature and individual block masses, we demonstrate that their phase behavior can alternatively be controlled through the use of blocks with random monomer sequencing. Block random copolymers (BRCs), i.e., diblock copolymers wherein one or both blocks is a random copolymer comprised of A and B repeat units, have been synthesized, and their phase behavior, expressed in terms of the order-disorder transition (ODT), has been investigated. Our results establish that, depending on the block composition contrast and molecular weight, BRCs can microphase-separate. We also report that the predicted ODT can be generated at relatively constant molecular weight and temperature with these new soft materials. This sequence-controlled synthetic strategy is extended to thermoplastic elastomeric triblock copolymers differing in chemistry and possessing a random-copolymer midblock.

  5. RIP Input Tables from WAPDEG for LA Design Selection: Enhanced Design Alternative II-3

    International Nuclear Information System (INIS)

    A.M. Monib

    1999-01-01

    The purpose of this calculation is to document (1) the Waste Package Degradation (WAPDEG) version 3.09 (CRWMS M and O 1998b. ''Software Routine Report for WAPDEG'' (Version 3.09)) simulations used to analyze degradation and failure of 2-cm thick titanium grade 7 corrosion resistant material (CRM) drip shields (that are placed over waste packages composed of a 2-cm thick Alloy 22 corrosion resistant material (CRM) as the outer barrier and an unspecified material to provide structural support as the inner barrier) as well as degradation and failure of the waste packages themselves, and (2) post-processing of these results into tables of drip shield/waste package degradation time histories suitable for use as input into the Integrated Probabilistic Simulator for Environmental Systems (RIP) version 5.19.01 (Golder Associates 1998) computer code. This calculation supports Performance Assessment analysis of the License Application Design Selection (LADS) Enhanced Design Alternative (EDA) II-3. The aging period in the EDA II design (CRWMS M and O 1999f. ''Design Input Request for LADS Phase II EDA Evaluations'', Item 1 Row 9 Column 3) was replaced in the case of EDA II-3 with 25 years preclosure ventilation, leading to a total of 50 years preclosure ventilation. The waste packages are line loaded in the repository and no backfill is used

  6. Postage for the messenger: Designating routes for Nuclear mRNA Export

    Science.gov (United States)

    Natalizio, Barbara J.; Wente, Susan R.

    2013-01-01

    Transcription of messenger(m) RNA occurs in the nucleus, making the translocation of mRNA across the nuclear envelope (NE) boundary a critical determinant of proper gene expression and cell survival. A major mRNA export route occurs via the NXF1-dependent pathway through the nuclear pore complexes (NPCs) embedded in the NE. However, recent findings have discovered new evidence supporting the existence of multiple mechanisms for crossing the NE, including both NPC-mediated and NE budding-mediated pathways. An analysis of the trans-acting factors and cis components that define these pathways reveals shared elements as well as mechanistic differences. We review here the current understanding of the mechanisms that characterize each pathway and highlight the determinants that influence mRNA transport fate. PMID:23583578

  7. An alternative retainer design for cleft patients: the "aesthetic" retainer.

    Science.gov (United States)

    Collins, Joanne M; Witcher, Thomas P; Jones, Vaughan S; Noar, Joseph H; Naini, Farhad B

    2010-11-01

    The objective of this report is to describe an original retainer design for retention following orthodontic treatment in cleft lip and palate patients in order to improve the aesthetics of anterior maxillary dentoalveolar cleft defects. The technique incorporates features of both traditional and modern retainer design. The advantages of the technique and fabrication process are described.

  8. Alternative designs of a superconducting synchronous generator: the Southampton approach

    OpenAIRE

    Goddard, K.F.; Lukasik, B.; Sykulski, J.K.

    2008-01-01

    The paper describes various designs undertaken at the University of Southampton for building both cored and coreless superconducting synchronous generators using high temperature superconducting (HTS) tapes. An overview of electromagnetic and mechanical design issues is presented and scalability is considered. Results are included for the full (original) size machine and extended to a double size unit.

  9. Implications of solar energy alternatives for community design

    Energy Technology Data Exchange (ETDEWEB)

    Santos, A.; Steinitz, C.

    1980-06-01

    A graduate-level studio at the Harvard School of Design explored how a policy of solar-based energy independence will influence the design of a new community of approximately 4500 housing units and other uses. Three large sites outside Tucson (a cooling problem), Atlanta (a humidity problem), and Boston (a heating problem) were selected. Each is typical of its region. A single program was assumed and designed for. Each site had two teams, one following a compact approach and one following a more dispersed approach. Each was free to choose the most appropriate mix of (solar) technology and scale, and was free to integrate energy and community in the design as it saw fit. These choice and integration issues are key areas where our experience may be of interest to those involved in community design and solar energy.

  10. RIP Input From WAPDEG for LA Design Selection: Enhanced Design Alternative II

    International Nuclear Information System (INIS)

    B.E. Bullard

    1999-01-01

    The purpose of this analysis is to identify and analyze concepts for the acquisition of data in support of the Performance Confirmation (PC) program at the potential subsurface nuclear waste repository at Yucca Mountain. This analysis is being prepared to document an investigation of design concepts, current available technology, technology trends, and technical issues associated with data acquisition during the PC period. This analysis utilizes the ''Performance Confirmation Plan'' (CRWMS M and O 2000b) to help define the scope for the PC data acquisition system. The focus of this analysis is primarily on the PC period for a minimum of 30 years after emplacement of the last waste package. The design of the data acquisition system shall allow for a closure deferral up to 300 years from initiation of waste emplacement. (CRWMS M and O 2000h, page 5-1). This analysis is a revision to and supercedes analysis, ''Performance Confirmation Data Acquisition System'', DI No. BCAI00000-017 17-0200-00002 Rev 00 (CRWMS M and O 1997), and incorporates the latest repository design changes following the M and O and DOE evaluation of a series of Enhanced Design Alternatives (EDAs), as described in the ''Enhanced Design Alternatives II Report'' (CRWMS M and O 1999d). Significant design changes include: thermal line loading of the emplacement drifts, closer spacing of the waste packages (WPs), wider spacing and fewer emplacement drifts, continuous ventilation of all active emplacement drifts, thinner walled WP designs which will increase external radiation levels, a 50-year repository closure option, inclusion of a drip-shield, exclusion of backfill, and new conceptual designs for the waste emplacement vehicles and equipment (Stroupe 2000). The scope and primary objectives of this analysis are to: (1) Review the criteria for design as presented in the Performance Confirmation Data Acquisition/Monitoring System Description Document, by way of the Input Transmittal, ''Performance

  11. Alternative Designs for the NSLS-II Injection Straight Section

    Energy Technology Data Exchange (ETDEWEB)

    Shaftan,T.; Heese, R.; Weihreter, E.; Willeke, F.; Rehak, M.; Meier, R.; Fliller, R.; Johnson, E. D.

    2009-05-04

    Brookhaven National Laboratory (BNL) is developing a state-of-the-art 3 GeV synchrotron light source, the NSLS-II [1]. The 9.3 meter-long injection straight section of its storage ring now fits a conventional injection set-up consisting of four kickers producing a closed bump, together with a DC septum and a pulsed septum. In this paper, we analyze an alternative option based on injection via a pulsed sextupole magnet. We discuss the dynamics of the injected and stored beams and, subsequently, the magnet's specifications and tolerances. We conclude by summarized the advantages and drawbacks of each injection scheme.

  12. A Kinetic Study of the Main Guaco Metabolites Using Syrup Formulation and the Identification of an Alternative Route of Coumarin Metabolism in Humans

    Science.gov (United States)

    Gasparetto, João Cleverson; Peccinini, Rosângela Gonçalves; de Francisco, Thais Martins Guimarães; Cerqueira, Letícia Bonâncio; Campos, Francinete Ramos; Pontarolo, Roberto

    2015-01-01

    For decades guaco species have been empirically used for the treatment of respiratory diseases. However, studies have shown that the toxic and therapeutic effects of the main guaco metabolites are dose-dependent, and none clinical study was done to evaluate the behavior of these substances in humans. In this work, a pilot study measuring the kinetic profile of the main guaco metabolites was performed leading to the knowledge of an alternative route of coumarin metabolism in humans. Initial screenings demonstrated that the administration of 60 mL of guaco syrup (single dose) did not provide sufficient levels of coumarin (COU), 7-hydroxycoumarin (7-HCOU), o-coumaric acid (OCA) and kaurenoic acid (KAU). The pharmacokinetic parameters were calculated by orally administering 60 mL of guaco syrup spiked with 1500 mg of COU. The kinetic study demonstrated that the plasmatic levels of 7-HCOU (considered the main metabolite of COU) were 10 times lower than the levels of COU, and the kinetic profile of 7-HCOU suggests sequential metabolism in the liver with low access of 7-HCOU to the systemic circulation. The study also demonstrated that OCA is one of the main bioavailable metabolites of COU. Therefore, the hydrolysis of the lactone ring forming a carboxylated compound is one of the possible routes of COU metabolism in humans. The half-lives of COU, 7-HCOU and OCA were approximately 4.0, 1.0 and 3.0 h, respectively and there was evidence that the recommended dosage of guaco syrup did not provide sufficient levels of COU, 7-HCOU or OCA to obtain a bronchodilation effect. Clinical studies are necessary to prove the efficacy and safety of products based on guaco. PMID:25757073

  13. Design Anthropology, Emerging Technologies and Alternative Computational Futures

    DEFF Research Database (Denmark)

    Smith, Rachel Charlotte

    Emerging technologies are providing a new field for design anthropological inquiry that unite experiences, imaginaries and materialities in complex way and demands new approaches to developing sustainable computational futures....

  14. Alternative designs of high-temperature superconducting synchronous generators

    OpenAIRE

    Goddard, K. F.; Lukasik, B.; Sykulski, J. K.

    2010-01-01

    This paper discusses the different possible designs of both cored and coreless superconducting synchronous generators using high-temperature superconducting (HTS) tapes, with particular reference to demonstrators built at the University of Southampton using BiSCCO conductors. An overview of the electromagnetic, thermal, and mechanical issues is provided, the advantages and drawbacks of particular designs are highlighted, the need for compromises is explained, and practical solutions are offer...

  15. Reliability improvement through alternative designs-A case study

    International Nuclear Information System (INIS)

    Kumar, Saurabh; Chattopadhyay, Gopi; Kumar, Uday

    2007-01-01

    In today's competitive world, reliability of equipment is extremely important to maintain quality and delivery deadlines. This is achieved by using proper maintenance and design changes for unreliable subsystems and components of a complex system. It is significant to develop a strategy for maintenance, replacement and design changes related to those subsystems and components. An analysis of down time along with causes is essential to identify the unreliable components and subsystems. This paper presents an analysis of failure data of solenoid coils of automatic internal grinding machine used in a bearing manufacturing plant. It analyses various replacement and change of design options such as introduction of pneumatic system in place of electromagnetic solenoids for improvement of reliability of the plunger movement mechanism

  16. Dynamic Carpooling in Urban Areas: Design and Experimentation with a Multi-Objective Route Matching Algorith

    Directory of Open Access Journals (Sweden)

    Matteo Mallus

    2017-02-01

    Full Text Available This paper focuses on dynamic carpooling services in urban areas to address the needs of mobility in real-time by proposing a two-fold contribution: a solution with novel features with respect to the current state-of-the-art, which is named CLACSOON and is available on the market; the analysis of the carpooling services performance in the urban area of the city of Cagliari through emulations. Two new features characterize the proposed solution: partial ridesharing, according to which the riders can walk to reach the driver along his/her route when driving to the destination; the possibility to share the ride when the driver has already started the ride by modelling the mobility to reach the driver destination. To analyse which features of the population bring better performance to changing the characteristics of the users, we also conducted emulations. When compared with current solutions, CLACSOON allows for achieving a decrease in the waiting time of around 55% and an increase in the driver and passenger success rates of around 4% and 10%,respectively. Additionally, the proposed features allowed for having an increase in the reduction of the CO2 emission by more than 10% with respect to the traditional carpooling service.

  17. Designing of routing algorithms in autonomous distributed data transmission system for mobile computing devices with ‘WiFi-Direct’ technology

    Science.gov (United States)

    Nikitin, I. A.; Sherstnev, V. S.; Sherstneva, A. I.; Botygin, I. A.

    2017-02-01

    The results of the research of existent routing protocols in wireless networks and their main features are discussed in the paper. Basing on the protocol data, the routing protocols in wireless networks, including search routing algorithms and phone directory exchange algorithms, are designed with the ‘WiFi-Direct’ technology. Algorithms without IP-protocol were designed, and that enabled one to increase the efficiency of the algorithms while working only with the MAC-addresses of the devices. The developed algorithms are expected to be used in the mobile software engineering with the Android platform taken as base. Easier algorithms and formats of the well-known route protocols, rejection of the IP-protocols enables to use the developed protocols on more primitive mobile devices. Implementation of the protocols to the engineering industry enables to create data transmission networks among working places and mobile robots without any access points.

  18. Multi-phase alternative current machine winding design | Khan ...

    African Journals Online (AJOL)

    ... single-phase to 18-phase excitation. Experimental results of a five-phase induction machine supplied from a static five-phase supply are provided to support the proposed design. Keywords: AC machine, Multi-phase machine, Stator winding, Five-phase. International Journal of Engineering, Science and Technology, Vol.

  19. Design element alternatives for stress-management intervention websites.

    Science.gov (United States)

    Williams, Reg A; Gatien, Gary; Hagerty, Bonnie

    2011-01-01

    Typical public and military-sponsored websites on stress and depression tend to be prescriptive. Some require users to complete lengthy questionnaires. Others reproduce printed flyers, papers, or educational materials not adapted for online use. Some websites require users to follow a prescribed path through the material. Stress Gym was developed as a first-level, evidence-based, website intervention to help U.S. military members learn how to manage mild to moderate stress and depressive symptoms using a self-help intervention with progress tracking and 24/7 availablility. It was designed using web-based, health-management intervention design elements that have been proven effective and users reported they prefer. These included interactivity, self-pacing, and pleasing aesthetics. Users learned how to manage stress by accessing modules they choose, and by practicing proven stress management strategies interactively immediately after login. Test results of Stress Gym with Navy members demonstrated that it was effective, with significant decreases in reported perceived stress levels from baseline to follow-up assessment. Stress Gym used design elements that may serve as a model for future websites to emulate and improve upon, and as a template against which to compare and contrast the design and functionality of future online, health-intervention websites. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Alternate Materials In Design Of Radioactive Material Packages

    International Nuclear Information System (INIS)

    Blanton, P.; Eberl, K.

    2010-01-01

    This paper presents a summary of design and testing of material and composites for use in radioactive material packages. These materials provide thermal protection and provide structural integrity and energy absorption to the package during normal and hypothetical accident condition events as required by Title 10 Part 71 of the Code of Federal Regulations. Testing of packages comprising these materials is summarized.

  1. Alternative Spring Break at the Savannah College of Art and Design: Engaging Art and Design Students in Community Service

    Science.gov (United States)

    Hoey, J. Joseph; Feld-Gore, Jeffrey A.

    2014-01-01

    This chapter describes the impact of an alternative spring break program on students at the Savannah College of Art and Design over a set of years as well as its effectiveness as a service-learning tool.

  2. RIP Input Tables From Wapdeg For LA Design Selection: Enhanced Design Alternative IIIb

    International Nuclear Information System (INIS)

    K.G. Mon; K.G. Mast; J.H. Lee

    1999-01-01

    The purpose of this calculation is to document the Waste Package Degradation (WAPDEG) version 3.09 (CRWMS M and O 1998b. 'Software Routine Report for WAPDEG' (Version 3.09)) simulations used to analyze degradation and failure of 2-cm thick titanium grade 7 corrosion resistant material (CRM) drip shields as well as degradation and failure of the waste packages over which they are placed. The waste packages are composed of two corrosion resistant materials (CRM) barriers. The outer barrier is composed of 2 cm of Alloy 22 and the inner barrier is composed of 1.5 cm of titanium grade 7. The WAPDEG simulation results are post-processed into tables of drip shield/waste package degradation time histories suitable for use as input into the Integrated Probabilistic Simulator for Environmental Systems (RIP) version 5.19.01 (Golder Associates 1998) computer code. This calculation supports Performance Assessment analysis of the License Application Design Selection (LADS) Enhanced Design Alternative IIIb

  3. Design of sustainable chemical processes: Systematic retrofit analysis, generation and evaluation alternatives

    DEFF Research Database (Denmark)

    Carvalho, Ana; Gani, Rafiqul; Matos, Henrique

    2008-01-01

    eliminating the need to identify trade-off-based solutions. These indicators are also able to reduce (where feasible) a set of safety indicators. An indicator sensitivity analysis algorithm has been added to the methodology to define design targets and to generate sustainable process alternatives. A computer......The objective of this paper is to present a generic and systematic methodology for identifying the feasible retrofit design alternatives of any chemical process. The methodology determines a set of mass and energy indicators from steady-state process data, establishes the operational and design...... targets, and through a sensitivity-based analysis, identifies the design alternatives that can match a set of design targets. The significance of this indicator-based method is that it is able to identify alternatives, where one or more performance criteria (factors) move in the same direction thereby...

  4. Emulsion Synthesis of Size-Tunable CH3NH3PbBr3 Quantum Dots: An Alternative Route toward Efficient Light-Emitting Diodes.

    Science.gov (United States)

    Huang, Hailong; Zhao, Fangchao; Liu, Lige; Zhang, Feng; Wu, Xian-gang; Shi, Lijie; Zou, Bingsuo; Pei, Qibing; Zhong, Haizheng

    2015-12-30

    We report a facile nonaqueous emulsion synthesis of colloidal halide perovskite quantum dots by controlled addition of a demulsifier into an emulsion of precursors. The size of resulting CH3NH3PbBr3 quantum dots can be tuned from 2 to 8 nm by varying the amount of demulsifier. Moreover, this emulsion synthesis also allows the purification of these quantum dots by precipitation from the colloidal solution and obtains solid-state powder which can be redissolved for thin film coating and device fabrication. The photoluminescence quantum yields of the quantum dots is generally in the range of 80-92%, and can be well-preserved after purification (∼80%). Green light-emitting diodes fabricated comprising a spin-cast layer of the colloidal CH3NH3PbBr3 quantum dots exhibited maximum current efficiency of 4.5 cd/A, power efficiency of 3.5 lm/W, and external quantum efficiency of 1.1%. This provides an alternative route toward high efficient solution-processed perovskite-based light-emitting diodes. In addition, the emulsion synthesis is versatile and can be extended for the fabrication of inorganic halide perovskite colloidal CsPbBr3 nanocrystals.

  5. Design study of CEPC Alternating Magnetic Field Booster

    CERN Document Server

    Bian, T; Cai, Y; Cui, X; Gao, J; Koratzinos, M; Su, F; Wang, D; Wang, Y; Xiao, M; Zhang, C

    2017-01-01

    The CEPC is a next generation circular e+e- collider proposed by China. The design of the full energy booster ring of the CEPC is especially challenging. The ejected beam energy is 120 GeV, but that of the injected beam is only 6 GeV. In a conventional approach, the low magnetic field of the main dipole magnets creates problems. We propose operating the booster ring as a large wiggler at low beam energies and as a normal ring at high energies to avoid the problem of very low dipole magnet fields.

  6. Electric market models, competitive model and alternative design

    International Nuclear Information System (INIS)

    Arnedillo, O.

    2007-01-01

    Almost ten years after the liberalization of the Spanish electric system, its market design has remained basically unchanged. Therefore, it is reasonable to consider whether the current model continues to be adequate or whether it should be changed. However, although the current model is far from the absolute optimum, it is suited to the current state of the Spanish system. Only some improvements, such as the reform of the capacity guarantee payment can be undertaken immediately. It will only be possible to undertake other improvements as distribution companies cover all of their electricity needs in forward contracts acquired through a competitive process. (Author)

  7. Alternative Design for Visual Identity of Yayasan Batik Indonesia

    Directory of Open Access Journals (Sweden)

    Puspita Putri Nugroho

    2015-01-01

    Full Text Available The research objective is to create a logo as the main visual identity. It is together with the graphic elements to support the overall visual identity of the organization and also apply the corporate identity to various applications to effectively foster the professional and trustworthy image of the organization as the foundation in Indonesia aiming for preserving and advancing Batik as the national asset. The writer used qualitative and quantitative method. Qualitative method included Face-to-face interview with the vice secretary of YBI, e-mail interview with the previous logo designer and direct survey to Textile Museum Jakarta and Batik Gallery; and Quantitative method through online survey. The result of the project is a new visual identity for Yayasan Batik Indonesia, which portrays its vision and mission. Design is the core in attaining an advantageous visual identity that could portray the image of the respected organization. When a consistency is applied through the whole visual identity, professional character of the organization is achieved. 

  8. 10 CFR 61.54 - Alternative requirements for design and operations.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Alternative requirements for design and operations. 61.54 Section 61.54 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.54 Alternative requirements for...

  9. Alternatives generation and analysis for phase I intermediate waste feed staging system design requirements

    Energy Technology Data Exchange (ETDEWEB)

    Britton, M.D.

    1996-10-02

    This document provides; a decision analysis summary; problem statement; constraints, requirements, and assumptions; decision criteria; intermediate waste feed staging system options and alternatives generation and screening; intermediate waste feed staging system design concepts; intermediate waste feed staging system alternative evaluation and analysis; and open issues and actions.

  10. An Energy-Efficient and Robust Multipath Routing Protocol for Cognitive Radio Ad Hoc Networks.

    Science.gov (United States)

    Singh, Kishor; Moh, Sangman

    2017-09-04

    Routing in cognitive radio ad hoc networks (CRAHNs) is a daunting task owing to dynamic topology, intermittent connectivity, spectrum heterogeneity, and energy constraints. Other prominent aspects such as channel stability, path reliability, and route discovery frequency should also be exploited. Several routing protocols have been proposed for CRAHNs in the literature. By stressing on one of the aspects more than any other, however, they do not satisfy all requirements of throughput, energy efficiency, and robustness. In this paper, we propose an energy-efficient and robust multipath routing (ERMR) protocol for CRAHNs by considering all prominent aspects including residual energy and channel stability in design. Even when the current routing path fails, the alternative routing path is immediately utilized. In establishing primary and alternative routing paths, both residual energy and channel stability are exploited simultaneously. Our simulation study shows that the proposed ERMR outperforms the conventional protocol in terms of network throughput, packet delivery ratio, energy consumption, and end-to-end delay.

  11. Virtual private network design : a proof of the tree routing conjecture on ring networks

    NARCIS (Netherlands)

    Hurkens, C.A.J.; Keijsper, J.C.M.; Stougie, L.

    2007-01-01

    A basic question in virtual private network (VPN) design is if the symmetric version of the problem always has an optimal solution which is a tree network. An affirmative answer would imply that the symmetric VPN problem is solvable in polynomial time. We give an affirmative answer in case the

  12. Virtual private network design: a proof of the tree routing conjecture on ring networks

    NARCIS (Netherlands)

    C.A.J. Hurkens (Cor); J.C.M. Keijsper; L. Stougie (Leen)

    2005-01-01

    htmlabstractA basic question in Virtual Private Network (VPN) design is if the symmetric version of the problem always has an optimal solution which is a tree network. An affirmative answer would imply that the symmetric VPN problem is solvable in polynomial time. We give an affirmative answer in

  13. The Linearized Simultaneous String-Design and Cargo-Routing Problem

    DEFF Research Database (Denmark)

    Plum, Christian Edinger Munk

    A global liner shipping network, consists of a billion dollar investment in assets. Designing this network, to minimize costs, while considering operational constraints is thus of great relevance. Empirical studies of the cost structure of a networks strings (ship rotations), show linear relation...

  14. Advancement in Nanoscale CMOS Device Design En Route to Ultra-Low-Power Applications

    Directory of Open Access Journals (Sweden)

    Subhra Dhar

    2011-01-01

    Full Text Available In recent years, the demand for power sensitive designs has grown significantly due to the fast growth of battery-operated portable applications. As the technology scaling continues unabated, subthreshold device design has gained a lot of attention due to the low-power and ultra-low-power consumption in various applications. Design of low-power high-performance submicron and deep submicron CMOS devices and circuits is a big challenge. Short-channel effect is a major challenge for scaling the gate length down and below 0.1 μm. Detailed review and potential solutions for prolonging CMOS as the leading information technology proposed by various researchers in the past two decades are presented in this paper. This paper attempts to categorize the challenges and solutions for low-power and low-voltage application and thus provides a roadmap for device designers working in the submicron and deep submicron region of CMOS devices separately.

  15. Inequality aspects of alternative CO2 agreement designs

    International Nuclear Information System (INIS)

    Welsch, Heinz

    1992-01-01

    In recent years, the expected climate change, due to the atmospheric accumulation of CO 2 and other trace gases, has become an increasingly important issue in energy policy. Given the important contribution of CO 2 to the greenhouse effect, and the global character of the problem, an international agreement on curbing CO 2 emissions is under current consideration. The design of such an agreement inevitably raises significant questions of equity and efficiency. In the international political debate, most emphasis is generally put on the distributive aspect. Interestingly, the discussion usually focuses on equity in terms of the distribution of emissions. From an economic perspective, it appears more natural to address the equity issue from the point of view of income. It is obvious that a given degree of abatement can have dramatically different economic effects in different countries. Of course, this aspect is implicitly at the centre of all CO 2 related equity considerations. In what follows, this issue will be addressed explicitly, by examining the applicability and the implications of various economic approaches to distributive justice. (author)

  16. Experiencing the Tourist City. The European Capital of Culture in Re-Designing City Routes

    OpenAIRE

    Manuela Guerreiro; Júlio Mendes

    2014-01-01

    Assuming that providing memorable experiences is the raison d’être of tourism industry, the city envisaged as a tourist destination should assume the tourist’s perspective when designing the settings and the most significant activities of a visit. Cities are facing new challenges, noticeably the globalisation of economies, the growing importance of the visual and the symbolic that define the current trends of consumption and the attractiveness of a place. Culture and events play a strategic r...

  17. Architectural design, interior decoration, and three-dimensional plumbing en route to multifunctional nanoarchitectures.

    Science.gov (United States)

    Long, Jeffrey W

    2007-09-01

    Ultraporous aperiodic solids, such as aerogels and ambigels, are sol-gel-derived equivalents of architectures. The walls are defined by the nanoscopic, covalently bonded solid network of the gel. The vast open, interconnected space characteristic of a building is represented by the three-dimensionally continuous nanoscopic pore network. We discuss how an architectural construct serves as a powerful metaphor that guides the chemist in the design of aerogel-like nanoarchitectures and in their physical and chemical transformation into multifunctional objects that yield high performance for rate-critical applications.

  18. Design analysis of engineered alternatives for the Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    Myers, J.; Djordjevic, S.; Adams, M.; Spangler, L.; Valdez, J.; Vetter, D.; Drez, P.

    1991-01-01

    The effectiveness of several engineered alternatives, designed to enhance the performance of the Waste Isolation Pilot Plant (WIPP), were evaluated relative to the performance of the baseline design. This evaluation was performed using a computer program referred to as the Design Analysis Model which couples salt creep closure, brine inflow, gas generation and dissipation to realistically simulate these interrelated processes over a 10,000 year period following the decommissioning of the repository. Analyses of the baseline design and nine alternative designs were performed for the undisturbed repository conditions, as well as three human intrusion events. Improvements in repository performance of up to four orders of magnitude were predicted for various engineered alternative waste forms. 6 refs., 8 figs., 1 tab

  19. Privacy by Design: An alternative to existing practice in safeguarding privacy

    NARCIS (Netherlands)

    Lieshout, M.J. van; Kool, L.; Schoonhoven, B. van; Jonge, M. de

    2011-01-01

    Purpose: The purpose of this paper is to develop/elaborate the concept Privacy by Design (PbD) and to explore the validity of the PbD framework. Design/methodology/approach: Attention for alternative concepts, such as PbD, which might offer surplus value in safeguarding privacy, is growing. Using

  20. Detailed design, fabrication and testing of an engineering prototype compensated pulsed alternator. Final report

    International Nuclear Information System (INIS)

    Bird, W.L. Jr.; Woodson, H.H.

    1980-03-01

    The design, fabrication, and test results of a prototype compensated pulsed alternator are discussed. The prototype compulsator is a vertical shaft single phase alternator with a rotating armature and salient pole stator. The machine is designed for low rep rate pulsed duty and is sized to drive a modified 10 cm Beta amplifier. The load consists of sixteen 15 mm x 20 mm x 112 cm long xenon flashlamps connected in parallel. The prototype compulsator generates an open circuit voltage of 6 kV, 180 Hz, at a maximum design speed of 5400 rpm. At maximum speed, the inertial energy stored in the compulsator rotor is 3.4 megajoules

  1. Total System Performance Assessment- License Appication Design Selection (LADS) Phase 1 Analysis for Post-Closure Ventilation (Design Alternative 3)

    Energy Technology Data Exchange (ETDEWEB)

    N. Erb

    1999-06-21

    The objective of this report is to evaluate the effect of potential changes to the TSPA-VA base case design on long-term repository performance. The design changes that are evaluated in this report include two configurations for post-closure ventilation. bow tie and open loop (Design Alternative 3 or D3). The following paragraphs briefly describe the motivation for evaluating post-closure ventilation. The bow tie configuration for post closure ventilation has been identified as a design alternative to the TSPA-VA base case model (CRWMS M&O, 1998a) that may provide improved performance by reducing the temperature and relative humidity within the waste package drifts. The bow tie configuration for post-closure ventilation is a closed-loop design. In this design. cross drifts are placed in pairs with each drift angling up on opposite sides of the repository. From the side, the cross drifts and side drifts form the shape of a bow tie. Movement of air through the system is driven by convective heating from the waste packages in the cross drifts. The open loop configuration is also being considered for its potential to improve post-closure performance of the repository. As with the bow tie configuration, the open loop is designed to decrease temperature and relative humidity within the waste package drifts. For the open loop configuration, air is drawn into the drifts from outside the mountain. The configuration for the repository with open-loop ventilation is similar to the base case repository design with a few added shafts to increase air flow through the drifts. This report documents the modeling assumptions and calculations conducted to evaluate the long-term performance of Design Alternative 3. The performance measure for this evaluation is dose rate. Results are presented that compare the dose-rate time histories with the new design alternatives to that for the TSPA-VA base case calculation (CRWMS M&O, 1998a).

  2. Design and synthesis of novel potent and selective integrin alphanubeta3 antagonists--novel synthetic routes to isoquinolinone, benzoxazinone, and quinazolinone acetates.

    Science.gov (United States)

    Seitz, Werner; Geneste, Hervé; Backfisch, Gisela; Delzer, Jürgen; Graef, Claudia; Hornberger, Wilfried; Kling, Andreas; Subkowski, Thomas; Zimmermann, Norbert

    2008-01-15

    An unexpected ring contraction of benzazepinone based alpha(nu)beta(3) antagonists led to the design of quinolinone-type derivatives. Novel and efficient synthetic routes to isoquinolinone, benzoxazinone, and quinazolinone acetates were established. Nanomolar alpha(nu)beta(3) antagonists based on these new scaffolds were prepared. Moreover, benzoxazinones 15a and 15b exhibited high microsomal stability and good permeability.

  3. Permutation Test Approach for Ordered Alternatives in Randomized Complete Block Design: A Comparative Study

    OpenAIRE

    GOKPINAR, Esra; GUL, Hasan; GOKPINAR, Fikri; BAYRAK, Hülya; OZONUR, Deniz

    2013-01-01

    Randomized complete block design is one of the most used experimental designs in statistical analysis. For testing ordered alternatives in randomized complete block design, parametric tests are used if random sample are drawn from Normal distribution. If normality assumption is not provide, nonparametric methods are used. In this study, we are interested nonparametric tests and we introduce briefly the nonparametric tests, such as Page, Modified Page and Hollander tests. We also give Permutat...

  4. Route selection issues for NWPA shipments

    International Nuclear Information System (INIS)

    Hill, C.V.; Harrison, I.G.

    1993-01-01

    Questions surrounding the designation of routes for the movement of spent nuclear fuel (SNF) and high-level radioactive waste (HLW) by the Office of Civilian Radioactive Waste Management (OCRWM) have broad implications. Federal regulations prescribe rules to be applied in the selection of highway routes. In most cases, these rules will lead to a clear selection of one route between an origin and destination point. However, in other cases, strict application of the regulations does not result in a clear choice of a preferred route. The regulations also provide discretion to State governments and carriers to select alternative routes to enhance the safety of the shipment. Railroad shipments of radioactive materials are not subject to Federal routing regulations. Since the railroads operate on private property, it has been assumed that they know the best way to move freight on their system. This discretion, while desirable for addressing unique local safety concerns or for responding to temporary safety concerns such as road problems, weather conditions, or construction areas, leads to significant opportunity for misunderstandings and uneasiness on the part of local residents

  5. Contact Graph Routing

    Science.gov (United States)

    Burleigh, Scott C.

    2011-01-01

    Contact Graph Routing (CGR) is a dynamic routing system that computes routes through a time-varying topology of scheduled communication contacts in a network based on the DTN (Delay-Tolerant Networking) architecture. It is designed to enable dynamic selection of data transmission routes in a space network based on DTN. This dynamic responsiveness in route computation should be significantly more effective and less expensive than static routing, increasing total data return while at the same time reducing mission operations cost and risk. The basic strategy of CGR is to take advantage of the fact that, since flight mission communication operations are planned in detail, the communication routes between any pair of bundle agents in a population of nodes that have all been informed of one another's plans can be inferred from those plans rather than discovered via dialogue (which is impractical over long one-way-light-time space links). Messages that convey this planning information are used to construct contact graphs (time-varying models of network connectivity) from which CGR automatically computes efficient routes for bundles. Automatic route selection increases the flexibility and resilience of the space network, simplifying cross-support and reducing mission management costs. Note that there are no routing tables in Contact Graph Routing. The best route for a bundle destined for a given node may routinely be different from the best route for a different bundle destined for the same node, depending on bundle priority, bundle expiration time, and changes in the current lengths of transmission queues for neighboring nodes; routes must be computed individually for each bundle, from the Bundle Protocol agent's current network connectivity model for the bundle s destination node (the contact graph). Clearly this places a premium on optimizing the implementation of the route computation algorithm. The scalability of CGR to very large networks remains a research topic

  6. Cell and stack design alternatives. Final report, August 1, 1978-December 31, 1979

    Energy Technology Data Exchange (ETDEWEB)

    Hoover, Jr., D. Q.; King, Robert B.

    1980-02-01

    The work described comprised the first phase of a planned six phase program to develop commercially viable phosphoric acid fuel cell (PAFC) driven on-site integrated energy systems (OS/IES). The Phase I effort was organized as three major technical tasks; (1) study of system design alternatives; (2) fuel cell design alternatives; and (3) methane conditioner study. It was decided that comprehensive modeling of one application would most effectively utilize the resources available for the study of systems design alternatives. A 48 unit apartment complex located in Albany, New York and built to HUD minimum standards was selected as being typical of the applications that will be served by the systems. The time varying space conditioning (HVAC) and electrical requirements including the effects of varying weather conditions, living habits and occupancy patterns were modeled. These requirements formed the basis for comparing the performance and cost of the alternative configurations with each other and with a conventional system. Five basic alternative OS/IES configurations plus four variations were selected from a preliminary list of 13 basic configurations for detailed performance nd cost evaluations. Study procedures and results are presented in detail. (WHK)

  7. Alternatives generation and analysis for the Phase I intermediate waste feed staging system design requirements

    Energy Technology Data Exchange (ETDEWEB)

    Claghorn, R.D., Fluor Daniel Hanford

    1997-02-06

    This alternatives generation and analysis (AGA) addresses the question: What is the design basis for the facilities required to stage low-level waste (LLW) feed to the Phase I private contractors? Alternative designs for the intermediate waste feed staging system were developed, analyzed, and compared. Based on these analyses, this document recommends installing mixer pumps in the central pump pit of double-shell tanks 241-AP-102 and 241-AP-104. Also recommended is installing decant/transfer pumps at these tanks. These recommendations have clear advantages in that they provide a low shedule impact/risk and the highest operability of all the alternatives investigated. This revision incorporates comments from the decision board.

  8. DESIGN WITH THE SENSES AND FOR THE SENSES: AN ALTERNATIVE TEACHING MODEL FOR DESIGN STUDIO

    OpenAIRE

    May al-Ibrashy; Tammy Gaber

    2010-01-01

    In the 1990s, Juhani Pallasmaa wrote a compact, yet, eye-opening book expressing his growing concern about the architectural profession’s waning ability to reference all the senses of the body in the design process. Bit by bit, the perceptive chasm between the architect and architecture was widening both in the design process and in the cognitive experience of existing architecture. More than a decade later, these concerns have heightened as the ramifications of this design divide appear in t...

  9. Demonstration of risk-based decision analysis in remedial alternative selection and design

    International Nuclear Information System (INIS)

    Evans, E.K.; Duffield, G.M.; Massmann, J.W.; Freeze, R.A.; Stephenson, D.E.

    1993-01-01

    This study demonstrates the use of risk-based decision analysis (Massmann and Freeze 1987a, 1987b) in the selection and design of an engineering alternative for groundwater remediation at a waste site at the Savannah River Site, a US Department of Energy facility in South Carolina. The investigation focuses on the remediation and closure of the H-Area Seepage Basins, an inactive disposal site that formerly received effluent water from a nearby production facility. A previous study by Duffield et al. (1992), which used risk-based decision analysis to screen a number of ground-water remediation alternatives under consideration for this site, indicated that the most attractive remedial option is ground-water extraction by wells coupled with surface water discharge of treated effluent. The aim of the present study is to demonstrate the iterative use of risk-based decision analysis throughout the design of a particular remedial alternative. In this study, we consider the interaction between two episodes of aquifer testing over a 6-year period and the refinement of a remedial extraction well system design. Using a three-dimensional ground-water flow model, this study employs (1) geostatistics and Monte Carlo techniques to simulate hydraulic conductivity as a stochastic process and (2) Bayesian updating and conditional simulation to investigate multiple phases of aquifer testing. In our evaluation of a remedial alternative, we compute probabilistic costs associated with the failure of an alternative to completely capture a simulated contaminant plume. The results of this study demonstrate the utility of risk-based decision analysis as a tool for improving the design of a remedial alternative through the course of phased data collection at a remedial site

  10. Computational issues in alternating projection algorithms for fixed-order control design

    DEFF Research Database (Denmark)

    Beran, Eric Bengt; Grigoriadis, K.

    1997-01-01

    Alternating projection algorithms have been introduced recently to solve fixed-order controller design problems described by linear matrix inequalities and non-convex coupling rank constraints. In this work, an extensive numerical experimentation using proposed benchmark fixed-order control desig...

  11. Long-term strategies for flood risk management: scenario definition and strategic alternative design

    NARCIS (Netherlands)

    Bruijn, de K.; Klijn, F.; McGahey, C.; Mens, M.; Wolfert, H.P.

    2008-01-01

    This report reviews some mainstream existing methods of scenario development and use, as well as experiences with the design and assessment of strategic alternatives for flood risk management. Next, a procedure and methods are proposed and discussed. Thirdly, the procedure and methods are tried on

  12. Single-Case Research Design: An Alternative Strategy for Evidence-Based Practice

    Science.gov (United States)

    Stapleton, Drue; Hawkins, Andrew

    2015-01-01

    Objective: The trend of utilizing evidence-based practice (EBP) in athletic training is now requiring clinicians, researchers, educators, and students to be equipped to both engage in and make judgments about research evidence. Single-case design (SCD) research may provide an alternative approach to develop such skills and inform clinical and…

  13. A comparison of alternative 60-mer probe designs in an in-situ synthesized oligonucleotide microarray

    Directory of Open Access Journals (Sweden)

    Fairbanks Benjamin D

    2006-04-01

    Full Text Available Abstract Background DNA microarrays have proven powerful for functional genomics studies. Several technologies exist for the generation of whole-genome arrays. It is well documented that 25mer probes directed against different regions of the same gene produce variable signal intensity values. However, the extent to which this is true for probes of greater length (60mers is not well characterized. Moreover, this information has not previously been reported for whole-genome arrays designed against bacteria, whose genomes may differ substantially in characteristics directly affecting microarray performance. Results We report here an analysis of alternative 60mer probe designs for an in-situ synthesized oligonucleotide array for the GC rich, β-proteobacterium Burkholderia cenocepacia. Probes were designed using the ArrayOligoSel3.5 software package and whole-genome microarrays synthesized by Agilent, Inc. using their in-situ, ink-jet technology platform. We first validated the quality of the microarrays as demonstrated by an average signal to noise ratio of >1000. Next, we determined that the variance of replicate probes (1178 total probes examined of identical sequence was 3.8% whereas the variance of alternative probes (558 total alternative probes examined designs was 9.5%. We determined that depending upon the definition, about 2.4% of replicate and 7.8% of alternative probes produced outlier conclusions. Finally, we determined none of the probe design subscores (GC content, internal repeat, binding energy and self annealment produced by ArrayOligoSel3.5 were predictive or probes that produced outlier signals. Conclusion Our analysis demonstrated that the use of multiple probes per target sequence is not essential for in-situ synthesized 60mer oligonucleotide arrays designed against bacteria. Although probes producing outlier signals were identified, the use of ratios results in less than 10% of such outlier conclusions. We also determined that

  14. Alternate MIMO AF relaying networks with interference alignment: Spectral efficient protocol and linear filter design

    KAUST Repository

    Park, Kihong

    2013-02-01

    In this paper, we study a two-hop relaying network consisting of one source, one destination, and three amplify-and-forward (AF) relays with multiple antennas. To compensate for the capacity prelog factor loss of 1/2$ due to the half-duplex relaying, alternate transmission is performed among three relays, and the inter-relay interference due to the alternate relaying is aligned to make additional degrees of freedom. In addition, suboptimal linear filter designs at the nodes are proposed to maximize the achievable sum rate for different fading scenarios when the destination utilizes a minimum mean-square error filter. © 1967-2012 IEEE.

  15. DESIGN WITH THE SENSES AND FOR THE SENSES: AN ALTERNATIVE TEACHING MODEL FOR DESIGN STUDIO

    Directory of Open Access Journals (Sweden)

    May al-Ibrashy

    2010-07-01

    Full Text Available In the 1990s, Juhani Pallasmaa wrote a compact, yet, eye-opening book expressing his growing concern about the architectural profession’s waning ability to reference all the senses of the body in the design process. Bit by bit, the perceptive chasm between the architect and architecture was widening both in the design process and in the cognitive experience of existing architecture. More than a decade later, these concerns have heightened as the ramifications of this design divide appear in the form of architecture whose divorced virtual quality has spilled over from the design process into built reality. The illusion of virtual reality – as achieved by 3D simulation in all its glories – has pulled the architect into a zone of false confidence where he/she feels that the design has come to life before it is built and that every corner and detail can be simulated and therefore understood. But can it be touched, smelt, tasted or heard? In fact, is even what we see on the screen anywhere close to what we see as we move bodily through its spaces? This phenomenon is addressed in a design studio run by the two authors of this paper. The purpose of the design studio, which is held in the Department of Architectural Engineering, of the Faculty of Engineering of the British University in Egypt, is to design a community centre linked to a place of worship within a residential compound currently under construction on the outskirts of Cairo. The graduating class of ten students is in the final and fourth year of a program that emphasized the engineering and project management aspects of architecture at the expense of theory and history of art and architecture. The university has no humanities or liberal arts program as yet, and students have minimal contact to arts within the university system. Contact hours in design studios are limited and design is mostly computer-aided. The need to re-emphasize the physical, tactile, polemic and holistic aspects

  16. Alternative Muon Front-end for the International Design Study (IDS)

    CERN Document Server

    Alekou, A; Martini, M; Prior, G; Rogers, C; Stratakis, D; Yoshikawa, C; Zisman, M

    2010-01-01

    We discuss alternative designs of the muon capture front end of the Neutrino Factory International Design Study (IDS). In the front end, a proton bunch on a target creates secondary pions that drift into a capture channel, decaying into muons. A sequence of RF cavities forms the resulting muon beams into strings of bunches of differing energies, aligns the bunches to (nearly) equal central energies, and initiates ionization cooling. This design is affected by limitations on accelerating gradients within magnetic fields. The effects of gradient limitations are explored, and mitigation strategies are presented

  17. Army Gas-Cooled Reactor Systems program: alternator final design report

    Energy Technology Data Exchange (ETDEWEB)

    1964-06-01

    The development and testing of a demonstration brushless alternator for the ML-1 mobile nuclear power plant is described. The brushless concept was selected after it became apparent that a conventional power generator could not satisfy the ML-1 weight and size requirements. The demonstration alternator fabricated and tested under this program did not meet all performance specifications; the efficiency was low and the unit could not be operated for significant periods of time without overheating. However, a large body of useful data was accumulated during the extensive development program. Of special interest are data on the rotor and stator design, the cooling requirements and on the distribution of eddy current losses. Analysis of the data indicates that a brushless alternator, only slightly larger and heavier than was specified for the ML-1, could be developed with a modest additional effort.

  18. Design of batch operations: Systematic methodology for generation and analysis of sustainable alternatives

    DEFF Research Database (Denmark)

    Carvalho, Ana; Matos, Henrique A.; Gani, Rafiqul

    2010-01-01

    the operational, environmental, economical and safety related problems inherent in the process (batch or continuous). Alternatives that are more sustainable, compared to a reference, are generated and evaluated by addressing one or more of the identified problems. A decomposition technique as well as a set......The objective of this paper is to present a new methodology that is able to generate, screen and identify sustainable alternatives to continuous chemical processes as well as processes operating in the batch mode. The methodology generates the sustainable (design) alternatives by locating...... of batch indicators for batch operations has been developed and added to the methodology so that a wide range of processes that operate in continuous mode, in semi-continuous and/or in batch modes can be improved. The principal calculation steps of the methodology for applications to continuous and batch...

  19. Predicting the effectiveness of road safety campaigns through alternative research designs.

    Science.gov (United States)

    Adamos, Giannis; Nathanail, Eftihia

    2016-12-01

    A large number of road safety communication campaigns have been designed and implemented in the recent years; however their explicit impact on driving behavior and road accident rates has been estimated in a rather low proportion. Based on the findings of the evaluation of three road safety communication campaigns addressing the issues of drinking and driving, seat belt usage, and driving fatigue, this paper applies different types of research designs (i.e., experimental, quasi-experimental, and non-experimental designs), when estimating the effectiveness of road safety campaigns, implements a cross-design assessment, and conducts a cross-campaign evaluation. An integrated evaluation plan was developed, taking into account the structure of evaluation questions, the definition of measurable variables, the separation of the target audience into intervention (exposed to the campaign) and control (not exposed to the campaign) groups, the selection of alternative research designs, and the appropriate data collection methods and techniques. Evaluating the implementation of different research designs in estimating the effectiveness of road safety campaigns, results showed that the separate pre-post samples design demonstrated better predictability than other designs, especially in data obtained from the intervention group after the realization of the campaign. The more constructs that were added to the independent variables, the higher the values of the predictability were. The construct that most affects behavior is intention, whereas the rest of the constructs have a lower impact on behavior. This is particularly significant in the Health Belief Model (HBM). On the other hand, behavioral beliefs, normative beliefs, and descriptive norms, are significant parameters for predicting intention according to the Theory of Planned Behavior (TPB). The theoretical and applied implications of alternative research designs and their applicability in the evaluation of road safety

  20. Crossbar H-mode drift-tube linac design with alternative phase focusing for muon linac

    Science.gov (United States)

    Otani, M.; Futatsukawa, K.; Hasegawa, K.; Kitamura, R.; Kondo, Y.; Kurennoy, S.

    2017-07-01

    We have developed a Crossbar H-mode (CH) drift-tube linac (DTL) design with an alternative phase focusing (APF) scheme for a muon linac, in order to measure the anomalous magnetic moment and electric dipole moment (EDM) of muons at the Japan Proton Accelerator Research Complex (J-PARC). The CH-DTL accelerates muons from β = v/c = 0.08 to 0.28 at an operational frequency of 324 MHz. The design and results are described in this paper.

  1. Alternatives for implementing burnup credit in the design and operation of spent fuel transport casks

    International Nuclear Information System (INIS)

    Sanders, T.L.; Lake, W.H.

    1989-01-01

    It is possible to develop an optimal strategy for implementing burnup credit in spent fuel transport casks. For transport, the relative risk is rapidly reduced if additional pre-transport controls such as a cavity dryness verifications are conducted prior to transport. Some other operational and design features that could be incorporated into a burnup credit cask strategy are listed. These examples represent many of the system features and alternatives already available for use in developing a broadly based criticality safety strategy for implementing burnup credit in the design and operation of spent fuel transport casks. 4 refs., 1 tab

  2. Energy-Efficient Routes for the Production of Gasoline from Biogas and Pyrolysis Oil-Process Design and Life-Cycle Assessment.

    Science.gov (United States)

    Sundaram, Smitha; Kolb, Gunther; Hessel, Volker; Wang, Qi

    2017-03-29

    Two novel routes for the production of gasoline from pyrolysis oil (from timber pine) and biogas (from ley grass) are simulated, followed by a cradle-to-gate life-cycle assessment of the two production routes. The main aim of this work is to conduct a holistic evaluation of the proposed routes and benchmark them against the conventional route of producing gasoline from natural gas. A previously commercialized method of synthesizing gasoline involves conversion of natural gas to syngas, which is further converted to methanol, and then as a last step, the methanol is converted to gasoline. In the new proposed routes, the syngas production step is different; syngas is produced from a mixture of pyrolysis oil and biogas in the following two ways: (i) autothermal reforming of pyrolysis oil and biogas, in which there are two reactions in one reactor (ATR) and (ii) steam reforming of pyrolysis oil and catalytic partial oxidation of biogas, in which there are separated but thermally coupled reactions and reactors (CR). The other two steps to produce methanol from syngas, and gasoline from methanol, remain the same. The purpose of this simulation is to have an ex-ante comparison of the performance of the new routes against a reference, in terms of energy and sustainability. Thus, at this stage of simulations, nonrigorous, equilibrium-based models have been used for reactors, which will give the best case conversions for each step. For the conventional production route, conversion and yield data available in the literature have been used, wherever available.The results of the process design showed that the second method (separate, but thermally coupled reforming) has a carbon efficiency of 0.53, compared to the conventional route (0.48), as well as the first route (0.40). The life-cycle assessment results revealed that the newly proposed processes have a clear advantage over the conventional process in some categories, particularly the global warming potential and primary

  3. Nebulized fluticasone propionate, a viable alternative to systemic route in the management of childhood moderate asthma attack: A double-blind, double-dummy study.

    Science.gov (United States)

    Demirca, Beyza Poplata; Cagan, Hasret; Kiykim, Ayca; Arig, Ulku; Arpa, Medeni; Tulunay, Aysin; Ozen, Ahmet; Karakoc-Aydiner, Elif; Baris, Safa; Barlan, I B

    2015-09-01

    In this study, we compared the clinical and immunological efficacy of nebulized corticosteroid (CS) to systemic route during treatment of moderate asthma attack in children. In this randomized, placebo-controlled, double-blind, double-dummy, prospective study, 81 children aged 12 months to 16 years experiencing asthma attack randomized into two treatment groups to receive, either; nebulized fluticasone propionate (n = 39, 2000 mcg/day) or oral methylprednisolone (n = 41, 1 mg/kg/day). Pulmonary index scores (PIS) were assessed at admission and at 1st, 4th, 8th, 12th, 24th, 48th hours, as well as, on day 7 and peak expiratory flow (PEF) at baseline and at the 7th day. Daily symptom and medication scores were recorded for all subjects. Immunological studies included phytohemagglutinin induced peripheral blood mononuclear cells culture supernatant for cytokine responses and CD4(+) CD25(+) FOXP3(+) T regulatory cell (T reg) percentage at baseline and day 7. The changes in PIS and PEF were similar in both treatment groups, with a significant improvement in both values at the 7th day, when compared to baseline. In both groups, significant reductions in symptom and medication scores were observed during the treatment period with no significant difference between the groups. At day 7 of intervention, phytohemagglutinin induced IL-4 level was significantly decreased only in the nebulized group compared to baseline (p = 0.01). Evaluation of cytokine responses by means of fold increase (stimulated (S)/unstimulated (US) ratio) revealed a significant reduction in IL-4, IL-5 and IL-17 only in nebulized group (p = 0.01, 0.01, 0.02; respectively). The fold increase value of IL-5 was significantly lower at 7th day in nebulized group when compared to systemic one (p = 0.02). At 7th day, although in both treatment groups the percentage of T reg cells was suppressed, it remained significantly higher in the nebule one when compared to systemic route (p = 0.04). In the management of

  4. Assessment of management alternatives for LWR wastes. Volume 6. Cost determination of the LWR waste management routes (treatment/conditioning/packaging/transport operations)

    International Nuclear Information System (INIS)

    Thiels, G.M.; Kowa, S.

    1993-01-01

    This report deals with the cost determination of a number of schemes for the treatment, conditioning, packaging, interim storage and transport operations of LWR wastes drawn up on the basis of Belgian, French and German practices in this particular area. In addition to the general procedure elaborated for determining, actualizing and scaling of plant and transport costs associated with the various schemes, in-depth calculations of each intermediate management stage are included in this report. This study is part of an overall theoretical exercise aimed at evaluating a selection of management routes for LWR waste based on economical and radiological criteria

  5. Alternative route for the synthesis of high surface-area η-Al{sub 2}O{sub 3}/Nb{sub 2}O{sub 5} catalyst from aluminum waste

    Energy Technology Data Exchange (ETDEWEB)

    Nogueira, Francisco G.E. [Departamento de Engenharia Química, Universidade Federal de São Carlos, CEP 13565-905, São Carlos, SP (Brazil); Asencios, Yvan J.O. [Departamento de Ciências do Mar, Universidade Federal de São Paulo, Av. Alm. Saldanha da Gama, 89, 11030-400, Santos, SP (Brazil); Rodella, Cristiane B. [Laboratório Nacional de Luz Sincrotron, Rua Giuseppe Máximo Scolfaro, 10.000 Polo II de Alta Tecnologia, 13083-970, Campinas, SP (Brazil); Porto, André L.M. [Departamento de Engenharia Química, Universidade Federal de São Carlos, CEP 13565-905, São Carlos, SP (Brazil); Assaf, Elisabete M., E-mail: eassaf@iqsc.usp.br [Instituto de Química de São Carlos, Universidade de São Paulo, Av. Trabalhador São Carlense, 400, 13560-970, São Carlos, SP (Brazil)

    2016-12-01

    This paper describes an alternative route for the production of a high-surface-area η-Al{sub 2}O{sub 3}/Nb{sub 2}O{sub 5} catalyst synthesized from aluminum waste and niobium ammonium oxalate (NH{sub 4}H{sub 2}[NbO−(C{sub 2}O{sub 4}){sub 3}]·3H{sub 2}O). The effects of thermal treatment on the morphology and crystal structure were examined by X-ray powder diffraction (XPD), surface area measurements (BET), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), X-ray fluorescence, dynamic scanning calorimetry (DSC) and thermogravimetry (TG) measurement. The catalysts were evaluated in the glycerol dehydration reaction. Catalytic tests were carried out with reactants in gas-phase with a fixed-bed reactor at 300° and 400 °C. - Highlights: • Alternative route for the production of a high-surface-area Al{sub 2}O{sub 3}/Nb{sub 2}O{sub 5} catalyst. • The catalyst was synthesized from aluminum waste and ammonium oxalato-niobate. • NbAl catalyst obtained showed high specific surface area (330 m{sup 2}/g). • The catalyst produced by this method showed promise in the dehydration of glycerol.

  6. Alternative design of inductive pointing device for oral interface for computers and wheelchairs.

    Science.gov (United States)

    Lontis, Eugen R; Andreasen Struijk, Lotte N S

    2012-01-01

    An inductive pointing device was designed and implemented successfully in a tongue controlled oral interface. Sensors were manufactured as an assembly of multilayer coils in the printed circuit board technology on two pads. The sensor pads were encapsulated together with electronics and battery in a mouthpiece, placed in the upper palate of the oral cavity. The PCB technology allowed surface activation of one or more sensors by gliding over the surface of the coils assembly of a small cylindrical unit attached to the tongue. The model consisted of 8 sensors and allowed real time proportional control of both speed and direction similar to a joystick. However, the size of the oral cavity, the number and geometry of the coil loops and characteristics of the activation unit impose limits in designing the sensors and call for an alternative layout design. Two alternative sensor designs are proposed in this paper, aiming to reduce the size of the sensor pad by one third, extending the target group, including children, and increasing the easiness of wear of the oral interface.

  7. Evaluation of alternative public transportation systems in Izmit urban transportation via axiomatic design method

    Directory of Open Access Journals (Sweden)

    Gülşen AKMAN

    2016-02-01

    Full Text Available In the world and in our country, most of urban transportation is performed by public transportation. Public transportation is a system which provides transportation easiness and opportunity to people, not to vehicles. Therefore, giving priority to public transportation system is necessary in organizing urban transportation. In this study, in order to reduce traffic intensity and to facilitate passenger transportation in Izmit urban transportation, It is tried to determine appropriate public transportation system. For this, firstly, alternatives which could be used for public transportation were determined. These alternatives are metro, metrobus, tram, light rail system and monorail. Afterwards, the variables affecting decision making about public transportation were determined. These variables are cost, transportation line features, vehicle characteristics, sensitivity to environment and customer satisfaction. Lastly, most appropriate public transportation system is proposed by using the axiomatic design method. As a result, light trail system and metrobus are determined as the most appropriate alternatives for Izmit public transportation system.Keywords: Urban transportation, Multi criteria decision making, Axiomatic design

  8. A Alternative Analog Circuit Design Methodology Employing Integrated Artificial Intelligence Techniques

    Science.gov (United States)

    Tuttle, Jeffery L.

    In consideration of the computer processing power now available to the designer, an alternative analog circuit design methodology is proposed. Computer memory capacities no longer require the reduction of the transistor operational characteristics to an imprecise formulation. Therefore, it is proposed that transistor modelling be abandoned in favor of fully characterized transistor data libraries. Secondly, availability of the transistor libraries would facilitate an automated selection of the most appropriate device(s) for the circuit being designed. More specifically, a preprocessor computer program to a more sophisticated circuit simulator (e.g. SPICE) is developed to assist the designer in developing the basic circuit topology and the selection of the most appropriate transistor. Once this is achieved, the circuit topology and selected transistor data library would be downloaded to the simulator for full circuit operational characterization and subsequent design modifications. It is recognized that the design process is enhanced by the use of heuristics as applied to iterative design results. Accordingly, an artificial intelligence (AI) interface is developed to assist the designer in applying the preprocessor results. To demonstrate the retrofitability of the AI interface to established programs, the interface is specifically designed to be as non-intrusive to the host code as possible. Implementation of the proposed methodology offers the potential to speed the design process, since the preprocessor both minimizes the required number of simulator runs and provides a higher acceptance potential of the initial and subsequent simulator runs. Secondly, part count reductions may be realizable since the circuit topologies are not as strongly driven by transistor limitations. Thirdly, the predicted results should more closely match actual circuit operations since the inadequacies of the transistor models have been virtually eliminated. Finally, the AI interface

  9. Crafting decision options and alternatives for designing cultural observation system using general morphological modelling

    Directory of Open Access Journals (Sweden)

    Jaber Moghaddampour

    2018-09-01

    Full Text Available According to connoisseurs, cultural system is encountering a fully new space in future decades and cultural indicators will be exposed by some dangers; for the same reason, cultural observation activities in management dialogue of Iran are emphasized; the concept of “observation” in Iran is facing with challenges including being far from the concepts of futures studies and the focus on “cultural indicators monitoring” while cultural engineering needs foresight and identification of affecting progressive and deterring factors on the culture. The present study aims at providing alternatives to design an observation system by considering the monitoring and scanning simultaneously to bring out strategic and futurist vision for cultural organizations. To this end, the solution space and morphological field of observation (parameters and values by using MA/Carma Viewer software package is designed based on the literature review and forming a five-member expert group and specialized conversations. Upon Internal Consistency Assessment of parameters and by considering some values as drivers, Parameters Activity Check was conducted to study the reactions by other parameters and values. After sense-making and proper understanding of the model behavior, an Inference and “What-If” model were devised; some configurations were studied and provided in order to aware a part of proper alternatives for designing a cultural observation system (two scenarios. Scenario selection is different due to contingencies and conditions of executing the process as well as the users’ needs and goals in cultural observation system and cultural organizations can make decisions and design detailed observation systems by using morphological models, solution space and alternatives provided in the present study and depended on their goals and needs.

  10. An alternative design of reference blocks during the ultrasonic of ferritic welded joints

    International Nuclear Information System (INIS)

    Rondon Torriente, S.; Galeano Alvarez, N.J.

    1996-01-01

    This paper describes an alternative design which can be used to construct the reference blocks required to make the sensibility adjustment during the ultrasonic control ferritic welded joints. The major possibilities of this design are seen when it's used together with the well known AVG method, however it can be properly used with the reference block technique. In addition, the most general facts to keep in mind during the construction of this means are outlined, and besides advantages and problems involved with the use of some basics reference reflectors of wide spread use. Also formulates are given that can be used to obtain the size of the disk shaped reflector corresponding to the basics reference reflectors that this design includes

  11. Design and first measurements of an alternative calorimetry chamber for the HZB quadrupole resonator

    CERN Document Server

    Keckert, Sebastian; Knobloch, Jens; Kugeler, Oliver

    2015-01-01

    The systematic research on superconducting thin films requires dedicated testing equipment. The Quadrupole Resonator (QPR) is a specialized tool to characterize the superconducting RF properties of circular planar samples. A calorimetric measurement of the RF surface losses allows the surface resistance to be measured with sub nano-ohm resolution. This measurement can be performed over a wide temperature and magnetic field range, at frequencies of 433, 866 and 1300 MHz. The system at Helmholtz-Zentrum Berlin (HZB) is based on a resonator built at CERN and has been optimized to lower peak electric fields and an improved resolution. In this paper the design of an alternative calorimetry chamber is presented, providing flat samples for coating which are easy changeable. All parts are connected by screwing connections and no electron beam welding is required. Furthermore this design enables exchangeability of samples between the resonators at HZB and CERN. First measurements with the new design show ambiguous r...

  12. Towards for Analyzing Alternatives of Interaction Design Based on Verbal Decision Analysis of User Experience

    Directory of Open Access Journals (Sweden)

    Marília Soares Mendes

    2010-04-01

    Full Text Available In domains (as digital TV, smart home, and tangible interfaces that represent a new paradigm of interactivity, the decision of the most appropriate interaction design solution is a challenge. HCI researchers have promoted in their works the validation of design alternative solutions with users before producing the final solution. User experience with technology is a subject that has also gained ground in these works in order to analyze the appropriate solution(s. Following this concept, a study was accomplished under the objective of finding a better interaction solution for an application of mobile TV. Three executable applications of mobile TV prototypes were built. A Verbal Decision Analysis model was applied on the investigations for the favorite characteristics in each prototype based on the user’s experience and their intentions of use. This model led a performance of a qualitative analysis which objectified the design of a new prototype.

  13. An alternative sol-gel route for the preparation of thin films in CeO2-TiO2 binary system

    International Nuclear Information System (INIS)

    Kidchob, Tongjit; Malfatti, Luca; Marongiu, Daniela; Enzo, Stefano; Innocenzi, Plinio

    2010-01-01

    Thin films of titania-ceria have been prepared via sol-gel processing by employing titanium and cerium chloride compounds in highly acidic conditions for the precursor sol. This sol-gel route allows obtaining titania-ceria and cerium titanate films, CeTi 2 O 6 , after thermal treatment in air. The films exhibit a high optical transparency which is modulated by controlling the composition and the thermal treatment. The materials have been characterized by X-ray diffraction, UV-visible spectroscopy, ellipsometric spectroscopy and atomic force microscopy. The titania-ceria films show, as a function of the composition, the formation of different phases after thermal treatment in air at 800 o C. In particular, with the composition Ce25-Ti75 we have obtained a pure cerium titanate phase, CeTi 2 O 6 , which can be formed only in a very strict range of compositions.

  14. An alternative sol-gel route for the preparation of thin films in CeO{sub 2}-TiO{sub 2} binary system

    Energy Technology Data Exchange (ETDEWEB)

    Kidchob, Tongjit; Malfatti, Luca; Marongiu, Daniela [Laboratorio di Scienza dei Materiali e Nanotecnologie, D.A.P., Universita di Sassari and CR-INSTM, Palazzo Pou Salid, Piazza Duomo 6, 07041 Alghero (Italy); Enzo, Stefano [Dipartimento di Chimica, Universita di Sassari, Via Vienna 2, 07100 Sassari (Italy); Innocenzi, Plinio, E-mail: plinio@uniss.i [Laboratorio di Scienza dei Materiali e Nanotecnologie, D.A.P., Universita di Sassari and CR-INSTM, Palazzo Pou Salid, Piazza Duomo 6, 07041 Alghero (Italy)

    2010-01-01

    Thin films of titania-ceria have been prepared via sol-gel processing by employing titanium and cerium chloride compounds in highly acidic conditions for the precursor sol. This sol-gel route allows obtaining titania-ceria and cerium titanate films, CeTi{sub 2}O{sub 6}, after thermal treatment in air. The films exhibit a high optical transparency which is modulated by controlling the composition and the thermal treatment. The materials have been characterized by X-ray diffraction, UV-visible spectroscopy, ellipsometric spectroscopy and atomic force microscopy. The titania-ceria films show, as a function of the composition, the formation of different phases after thermal treatment in air at 800 {sup o}C. In particular, with the composition Ce25-Ti75 we have obtained a pure cerium titanate phase, CeTi{sub 2}O{sub 6}, which can be formed only in a very strict range of compositions.

  15. Alternative Ultrasound Gel for a Sustainable Ultrasound Program: Application of Human Centered Design.

    Directory of Open Access Journals (Sweden)

    Margaret Salmon

    Full Text Available This paper describes design of a low cost, ultrasound gel from local products applying aspects of Human Centered Design methodology. A multidisciplinary team worked with clinicians who use ultrasound where commercial gel is cost prohibitive and scarce. The team followed the format outlined in the Ideo Took Kit. Research began by defining the challenge "how to create locally available alternative ultrasound gel for a low-resourced environment? The "End-Users," were identified as clinicians who use ultrasound in Democratic Republic of the Congo and Ethiopia. An expert group was identified and queried for possible alternatives to commercial gel. Responses included shampoo, oils, water and cornstarch. Cornstarch, while a reasonable solution, was either not available or too expensive. We then sought deeper knowledge of locally sources materials from local experts, market vendors, to develop a similar product. Suggested solutions gleaned from these interviews were collected and used to create ultrasound gel accounting for cost, image quality, manufacturing capability. Initial prototypes used cassava root flour from Great Lakes Region (DRC, Rwanda, Uganda, Tanzania and West Africa, and bula from Ethiopia. Prototypes were tested in the field and resulting images evaluated by our user group. A final prototype was then selected. Cassava and bula at a 32 part water, 8 part flour and 4 part salt, heated, mixed then cooled was the product design of choice.

  16. Alternative Ultrasound Gel for a Sustainable Ultrasound Program: Application of Human Centered Design.

    Science.gov (United States)

    Salmon, Margaret; Salmon, Christian; Bissinger, Alexa; Muller, Mundenga Mutendi; Gebreyesus, Alegnta; Geremew, Haimanot; Wendel, Sarah K; Wendell, Sarah; Azaza, Aklilu; Salumu, Maurice; Benfield, Nerys

    2015-01-01

    This paper describes design of a low cost, ultrasound gel from local products applying aspects of Human Centered Design methodology. A multidisciplinary team worked with clinicians who use ultrasound where commercial gel is cost prohibitive and scarce. The team followed the format outlined in the Ideo Took Kit. Research began by defining the challenge "how to create locally available alternative ultrasound gel for a low-resourced environment? The "End-Users," were identified as clinicians who use ultrasound in Democratic Republic of the Congo and Ethiopia. An expert group was identified and queried for possible alternatives to commercial gel. Responses included shampoo, oils, water and cornstarch. Cornstarch, while a reasonable solution, was either not available or too expensive. We then sought deeper knowledge of locally sources materials from local experts, market vendors, to develop a similar product. Suggested solutions gleaned from these interviews were collected and used to create ultrasound gel accounting for cost, image quality, manufacturing capability. Initial prototypes used cassava root flour from Great Lakes Region (DRC, Rwanda, Uganda, Tanzania) and West Africa, and bula from Ethiopia. Prototypes were tested in the field and resulting images evaluated by our user group. A final prototype was then selected. Cassava and bula at a 32 part water, 8 part flour and 4 part salt, heated, mixed then cooled was the product design of choice.

  17. Preliminary Assessment of Two Alternative Core Design Concepts for the Special Purpose Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Sterbentz, James W. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Werner, James E. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hummel, Andrew J. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kennedy, John C. [Idaho National Lab. (INL), Idaho Falls, ID (United States); O' Brien, Robert C. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Dion, Axel M. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Wright, Richard N. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ananth, Krishnan P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-11-01

    The Special Purpose Reactor (SPR) is a small 5 MWt, heat pipe-cooled, fast reactor based on the Los Alamos National Laboratory (LANL) Mega-Power concept. The LANL concept features a stainless steel monolithic core structure with drilled channels for UO2 pellet stacks and evaporator sections of the heat pipes. Two alternative active core designs are presented here that replace the monolithic core structure with simpler and easier to manufacture fuel elements. The two new core designs are simply referred to as Design A and Design B. In addition to ease of manufacturability, the fuel elements for both Design A and Design B can be individually fabricated, assembled, inspected, tested, and qualified prior to their installation into the reactor core leading to greater reactor system reliability and safety. Design A fuel elements will require the development of a new hexagonally-shaped UO2 fuel pellet. The Design A configuration will consist of an array of hexagonally-shaped fuel elements with each fuel element having a central heat pipe. This hexagonal fuel element configuration results in four radial gaps or thermal resistances per element. Neither the fuel element development, nor the radial gap issue are deemed to be serious and should not impact an aggressive reactor deployment schedule. Design B uses embedded arrays of heat pipes and fuel pins in a double-wall tank filled with liquid metal sodium. Sodium is used to thermally bond the heat pipes to the fuel pins, but its usage may create reactor transportation and regulatory challenges. An independent panel of U.S. manufacturing experts has preliminarily assessed the three SPR core designs and views Design A as simplest to manufacture. Herein are the results of a preliminary neutronic, thermal, mechanical, material, and manufacturing assessment of both Design A and Design B along with comparisons to the LANL concept (monolithic core structure). Despite the active core differences, all three reactor concepts behave

  18. Applications of RADTRAN 4 to route-specific analysis

    International Nuclear Information System (INIS)

    Neuhauser, Sieglinde; Weiner, Ruth F.

    1992-01-01

    The transportation risk evaluation code RADTRAN 4 is designed to evaluate doses and risks associated with the transportation of radioactive materials. RADTRAN 4 may be used to calculate dose consequences for incident- free transportation and dose risks for accidents. Consequences of normal (or incident-free) transportation include doses to crew members, persons at stops, and members of the public sharing a route segment (on-link) and residing near the segment (off-link) during normal transportation. These dose estimates are not multiplied by a probability factor and, hence, are referred to as dose consequences. Calculated doses that might be incurred during accidents arc multiplied by the probabilities of those accidents, and hence are referred to as dose risks. RADTRAN 4 includes a LINK option that allows the user to characterize each link or segment of a transportation route in greater detail than that provided by average or default values for route-related parameters. The LINK option increases the flexibility of the code in several ways: LINK allows the same route segment to be evaluated under a variety of conditions. This capability may be used to prepare environmental documentation and to evaluate alternative routes under V.S. Department of Transportation Docket HM-164 (49 CFR 171-177); LINK capability may be used to assess the impact of projected population shifts on transportation routes; LINK facilitates comparison of the national average data included as defaults in RADTRAN with available 'route-specific' data. (author)

  19. Utility of an alternative bicycle commute route of lower proximity to motorised traffic in decreasing exposure to ultra-fine particles, respiratory symptoms and airway inflammation – a structured exposure experiment

    Science.gov (United States)

    2013-01-01

    Background Bicycle commuting in an urban environment of high air pollution is known to be a potential health risk, especially for susceptible individuals. While risk management strategies aimed to reduce exposure to motorised traffic emissions have been suggested, only limited studies have assessed the utility of such strategies in real-world circumstances. Objectives The potential to lower exposure to ultrafine particles (UFP; bicycle commuting by reducing proximity to motorised traffic was investigated with real-time air pollution and intermittent acute inflammatory measurements in healthy individuals using their typical higher proximity, and an alternative lower proximity, bicycle commute route. Methods Thirty-five healthy adults (mean ± SD: age = 39 ± 11 yr; 29% female) completed two return trips, one each in the condition of their typical route (HIGH) and a pre-determined alternative route of lower proximity to motorised traffic (LOW); proximity being determined by the proportion of on-road cycle paths. Particle number concentration (PNC) and diameter (PD) were monitored in-commute in real-time. Acute inflammatory indices of respiratory symptoms (as a scalar of frequency from very low to very high / 1 to 5), lung function and spontaneous sputum (for inflammatory cell analyses) were collected immediately pre-commute, and immediately and three hours post-commute. Results In the condition of LOW, compared to in the condition of HIGH, there was a significant decrease in mean PNC (1.91 x e4 ± 0.93 × e4 ppcc vs. 2.95 × e4 ± 1.50 × e4 ppcc; p ≤ 0.001), and the mean frequency of in-commute offensive odour detection (2.1 vs. 2.8; p = 0.019), dust and soot observation (1.7 vs. 2.3; p = 0.038) and nasopharyngeal irritation (1.5 vs. 1.9; p = 0.007). There were no significant differences between LOW and HIGH in the commute distance and duration (12.8 ± 7.1 vs. 12.0 ± 6.9 km and 44 ± 17 vs. 42 ± 17 min, respectively), or other indices of acute airway

  20. Utility of an alternative bicycle commute route of lower proximity to motorised traffic in decreasing exposure to ultra-fine particles, respiratory symptoms and airway inflammation--a structured exposure experiment.

    Science.gov (United States)

    Cole-Hunter, Tom; Jayaratne, Rohan; Stewart, Ian; Hadaway, Matthew; Morawska, Lidia; Solomon, Colin

    2013-04-08

    Bicycle commuting in an urban environment of high air pollution is known to be a potential health risk, especially for susceptible individuals. While risk management strategies aimed to reduce exposure to motorised traffic emissions have been suggested, only limited studies have assessed the utility of such strategies in real-world circumstances. The potential to lower exposure to ultrafine particles (UFP; bicycle commuting by reducing proximity to motorised traffic was investigated with real-time air pollution and intermittent acute inflammatory measurements in healthy individuals using their typical higher proximity, and an alternative lower proximity, bicycle commute route. Thirty-five healthy adults (mean ± SD: age = 39 ± 11 yr; 29% female) completed two return trips, one each in the condition of their typical route (HIGH) and a pre-determined alternative route of lower proximity to motorised traffic (LOW); proximity being determined by the proportion of on-road cycle paths. Particle number concentration (PNC) and diameter (PD) were monitored in-commute in real-time. Acute inflammatory indices of respiratory symptoms (as a scalar of frequency from very low to very high / 1 to 5), lung function and spontaneous sputum (for inflammatory cell analyses) were collected immediately pre-commute, and immediately and three hours post-commute. In the condition of LOW, compared to in the condition of HIGH, there was a significant decrease in mean PNC (1.91 x e4 ± 0.93 × e4 ppcc vs. 2.95 × e4 ± 1.50 × e4 ppcc; p ≤ 0.001), and the mean frequency of in-commute offensive odour detection (2.1 vs. 2.8; p = 0.019), dust and soot observation (1.7 vs. 2.3; p = 0.038) and nasopharyngeal irritation (1.5 vs. 1.9; p = 0.007). There were no significant differences between LOW and HIGH in the commute distance and duration (12.8 ± 7.1 vs. 12.0 ± 6.9 km and 44 ± 17 vs. 42 ± 17 min, respectively), or other indices of acute airway inflammation. Exposure to PNC and offensive

  1. Feed-water heaters alternative design comparison; Comparacion de disenos alternativos de calentadores

    Energy Technology Data Exchange (ETDEWEB)

    Torres Toledano, Gerardo [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1988-12-31

    A procedure is presented for the alternative design comparison of feed water heaters, based in the failure records of damaged tubes during operation. The procedure is used for cases in which non-continuous or random inspections are made to the feed-water heaters. [Espanol] Se presenta un procedimiento para comparar disenos alternativos de calentadores, basandose en los registros de fallas de los tubos rotos acumuladas durante su operacion. El procedimiento se emplea para casos en los que se realizan inspecciones a los calentadores no continuas, ya sea periodicas o al azar.

  2. Retrofitting a spent fuel pool spray system for alternative cooling as a strategy for beyond design basis events

    Energy Technology Data Exchange (ETDEWEB)

    Hartmann, Christoph; Vujic, Zoran [Westinghouse Electric Germany GmbH, Mannheim (Germany)

    2017-06-15

    Due to requirements for nuclear power plants to withstand beyond design basis accidents, including events such as happened in 2011 in the Fukushima Daiichi Nuclear Power Plant in Japan, alternative cooling of spent fuel is needed. Alternative spent fuel cooling can be provided by a retrofitted spent fuel pool spray system based on the AP1000 plant design. As part of Krsko Nuclear Power Plant's Safety Upgrade Program, Krsko Nuclear Power Plant decided on, and Westinghouse successfully designed a retrofit of the AP1000 {sup registered} plant spent fuel pool spray system to provide alternative spent fuel cooling.

  3. Two preliminary alternative designs for the gravity support of ITER toroidal field magnet

    International Nuclear Information System (INIS)

    Hou Binglin; Pan Chuanhong; Li Pengyuan; Zhang Nianman

    2009-01-01

    According to the original reference design, the gravity support pedestal (GSP) of ITER toroidal field magnet will be very difficult to fabricate because of large vacuum electronic welding, and therefore, two conceptual alternative designs, 'split vacuum electronic welding option' and 'bolt clamping option', are put forward. The preliminary buckling analyses with FEM (finite element method) and hand calculation show that there are enough safety margin in two options and both of them are feasible. Even though the 'split vacuum electronic welding option' makes the welding easier (in which GSP is split into two halves and thereby no large vacuum-chamber is needed), there are more advantages in the 'bolt clamping option' (where no welding is needed), such as the GSP fabrication is simple, the reject rate is low, the cost is much lower, and the producing time is shortened. Comparably, the 'bolt clamping option' is strongly recommended. (authors)

  4. Preliminary design study of an alternate heat source assembly for a Brayton isotope power system

    Science.gov (United States)

    Strumpf, H. J.

    1978-01-01

    Results are presented for a study of the preliminary design of an alternate heat source assembly (HSA) intended for use in the Brayton isotope power system (BIPS). The BIPS converts thermal energy emitted by a radioactive heat source into electrical energy by means of a closed Brayton cycle. A heat source heat exchanger configuration was selected and optimized. The design consists of a 10 turn helically wound Hastelloy X tube. Thermal analyses were performed for various operating conditions to ensure that post impact containment shell (PICS) temperatures remain within specified limits. These limits are essentially satisfied for all modes of operation except for the emergency cooling system for which the PICS temperatures are too high. Neon was found to be the best choice for a fill gas for auxiliary cooling system operation. Low cycle fatigue life, natural frequency, and dynamic loading requirements can be met with minor modifications to the existing HSA.

  5. A Modified Jonckheere Test Statistic for Ordered Alternatives in Repeated Measures Design

    Directory of Open Access Journals (Sweden)

    Hatice Tül Kübra AKDUR

    2016-09-01

    Full Text Available In this article, a new test based on Jonckheere test [1] for  randomized blocks which have dependent observations within block is presented. A weighted sum for each block statistic rather than the unweighted sum proposed by Jonckheereis included. For Jonckheere type statistics, the main assumption is independency of observations within block. In the case of repeated measures design, the assumption of independence is violated. The weighted Jonckheere type statistic for the situation of dependence for different variance-covariance structure and the situation based on ordered alternative hypothesis structure of each block on the design is used. Also, the proposed statistic is compared to the existing test based on Jonckheere in terms of type I error rates by performing Monte Carlo simulation. For the strong correlations, circular bootstrap version of the proposed Jonckheere test provides lower rates of type I error.

  6. SustainPro - A tool for systematic process analysis, generation and evaluation of sustainable design alternatives

    DEFF Research Database (Denmark)

    Carvalho, Ana; Matos, Henrique A.; Gani, Rafiqul

    2013-01-01

    . The software tool is based on the implementation of an extended systematic methodology for sustainable process design (Carvalho et al. 2008 and Carvalho et al. 2009). Using process information/data such as the process flowsheet, the associated mass / energy balance data and the cost data, SustainPro guides......Chemical processes are continuously facing challenges from the demands of the global market related to economics, environment and social issues. This paper presents the development of a software tool (SustainPro) and its application to chemical processes operating in batch or continuous modes...... the user through the necessary steps according to work-flow of the implemented methodology. At the end the design alternatives, are evaluated using environmental impact assessment tools and safety indices. The extended features of the methodology incorporate Life Cycle Assessment analysis and economic...

  7. A better alternative to stratified permuted block design for subject randomization in clinical trials.

    Science.gov (United States)

    Zhao, Wenle

    2014-12-30

    Stratified permuted block randomization has been the dominant covariate-adaptive randomization procedure in clinical trials for several decades. Its high probability of deterministic assignment and low capacity of covariate balancing have been well recognized. The popularity of this sub-optimal method is largely due to its simplicity in implementation and the lack of better alternatives. Proposed in this paper is a two-stage covariate-adaptive randomization procedure that uses the block urn design or the big stick design in stage one to restrict the treatment imbalance within each covariate stratum, and uses the biased-coin minimization method in stage two to control imbalances in the distribution of additional covariates that are not included in the stratification algorithm. Analytical and simulation results show that the new randomization procedure significantly reduces the probability of deterministic assignments, and improve the covariate balancing capacity when compared to the traditional stratified permuted block randomization. Copyright © 2014 John Wiley & Sons, Ltd.

  8. Alternating copolymerization of propylene oxide with biorenewable terpene-based cyclic anhydrides: a sustainable route to aliphatic polyesters with high glass transition temperatures.

    Science.gov (United States)

    Van Zee, Nathan J; Coates, Geoffrey W

    2015-02-23

    The alternating copolymerization of propylene oxide with terpene-based cyclic anhydrides catalyzed by chromium, cobalt, and aluminum salen complexes is reported. The use of the Diels-Alder adduct of α-terpinene and maleic anhydride as the cyclic anhydride comonomer results in amorphous polyesters that exhibit glass transition temperatures (Tg ) of up to 109 °C. The polymerization conditions and choice of catalyst have a dramatic impact on the molecular weight distribution, the relative stereochemistry of the diester units along the polymer chain, and ultimately the Tg of the resulting polymer. The aluminum salen complex exhibits exceptional selectivity for copolymerization without transesterification or epimerization side reactions. The resulting polyesters are highly alternating and have high molecular weights and narrow polydispersities. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. A Visual Analytics Based Decision Support Methodology For Evaluating Low Energy Building Design Alternatives

    Science.gov (United States)

    Dutta, Ranojoy

    The ability to design high performance buildings has acquired great importance in recent years due to numerous federal, societal and environmental initiatives. However, this endeavor is much more demanding in terms of designer expertise and time. It requires a whole new level of synergy between automated performance prediction with the human capabilities to perceive, evaluate and ultimately select a suitable solution. While performance prediction can be highly automated through the use of computers, performance evaluation cannot, unless it is with respect to a single criterion. The need to address multi-criteria requirements makes it more valuable for a designer to know the "latitude" or "degrees of freedom" he has in changing certain design variables while achieving preset criteria such as energy performance, life cycle cost, environmental impacts etc. This requirement can be met by a decision support framework based on near-optimal "satisficing" as opposed to purely optimal decision making techniques. Currently, such a comprehensive design framework is lacking, which is the basis for undertaking this research. The primary objective of this research is to facilitate a complementary relationship between designers and computers for Multi-Criterion Decision Making (MCDM) during high performance building design. It is based on the application of Monte Carlo approaches to create a database of solutions using deterministic whole building energy simulations, along with data mining methods to rank variable importance and reduce the multi-dimensionality of the problem. A novel interactive visualization approach is then proposed which uses regression based models to create dynamic interplays of how varying these important variables affect the multiple criteria, while providing a visual range or band of variation of the different design parameters. The MCDM process has been incorporated into an alternative methodology for high performance building design referred to as

  10. Latent factors and route choice behaviour

    DEFF Research Database (Denmark)

    Prato, Carlo Giacomo

    . A reliable dataset was prepared through measures of internal consistency and sampling adequacy, and data were analyzed with a proper application of factor analysis to the route choice context. For the dataset obtained from the survey, six latent constructs affecting driver behaviour were extracted and scores...... of drivers did not minimize travel time and distance, while simulation techniques were suitable to produce realistic alternative paths in the choice set generation phase. Several route choice models were evaluated: Multinomial Logit, C-Logit, Path Size Logit, Generalized Nested Logit, Cross Nested Logit...... and Link Nested Logit. Estimates were produced from model specifications that considered level-of-service, label and facility dummy variables. Moreover, a modelling framework was designed to represent drivers’ choices as affected by the latent constructs extracted with factor analysis. Previous experience...

  11. Design of the smart home system based on the optimal routing algorithm and ZigBee network.

    Science.gov (United States)

    Jiang, Dengying; Yu, Ling; Wang, Fei; Xie, Xiaoxia; Yu, Yongsheng

    2017-01-01

    To improve the traditional smart home system, its electric wiring, networking technology, information transmission and facility control are studied. In this paper, we study the electric wiring, networking technology, information transmission and facility control to improve the traditional smart home system. First, ZigBee is used to replace the traditional electric wiring. Second, a network is built to connect lots of wireless sensors and facilities, thanks to the capability of ZigBee self-organized network and Genetic Algorithm-Particle Swarm Optimization Algorithm (GA-PSOA) to search for the optimal route. Finally, when the smart home system is connected to the internet based on the remote server technology, home environment and facilities could be remote real-time controlled. The experiments show that the GA-PSOA reduce the system delay and decrease the energy consumption of the wireless system.

  12. Catalyst-controlled stereoselective olefin metathesis as a principal strategy in multistep synthesis design: a concise route to (+)-neopeltolide.

    Science.gov (United States)

    Yu, Miao; Schrock, Richard R; Hoveyda, Amir H

    2015-01-02

    Molybdenum-, tungsten-, and ruthenium-based complexes that control the stereochemical outcome of olefin metathesis reactions have been recently introduced. However, the complementary nature of these systems through their combined use in multistep complex molecule synthesis has not been illustrated. A concise diastereo- and enantioselective route that furnishes the anti-proliferative natural product neopeltolide is now disclosed. Catalytic transformations are employed to address every stereochemical issue. Among the featured processes are an enantioselective ring-opening/cross-metathesis promoted by a Mo monoaryloxide pyrrolide (MAP) complex and a macrocyclic ring-closing metathesis that affords a trisubstituted alkene and is catalyzed by a Mo bis(aryloxide) species. Furthermore, Z-selective cross-metathesis reactions, facilitated by Mo and Ru complexes, have been employed in the stereoselective synthesis of the acyclic dienyl moiety of the target molecule. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Clean Air Program : Design Guidelines for Bus Transit Systems Using Alcohol Fuel (Methanol and Ethanol) as an Alternative Fuel

    Science.gov (United States)

    1996-08-01

    Although there are over one thousand transit buses in revenue service in the U.S. that are powered by alternative fuels, there are no comprehensive guidelines for the safe design and operation of alternative fuel facilities and vehicles for transit s...

  14. An alternative design for a metal image slicing IFU for EAGLE

    Science.gov (United States)

    Dubbeldam, Cornelis M.; Robertson, David J.; Rolt, Stephen; Talbot, R. Gordon

    2012-09-01

    The Centre for Advanced Instrumentation (CfAI) of Durham University (UK) has developed a conceptual design for the Integral Field Unit (IFU) for EAGLE based on diamond-machined monolithic multi-faceted metal-mirror arrays as an alternative to the glass IFU which is currently baselined. The CfAI has built up substantial expertise with the design, manufacture, integration, alignment and acceptance testing of such systems, through the successful development of IFUs for the Gemini Near-InfraRed Spectrograph (GNIRS) and JWST NIRSpec and 24 IFUs for ESO’s K-band Multi-Object Spectrometer (KMOS). The unprecedented performance of the KMOS IFUs (Strehl risks and cost. Through the timely completion of the KMOS IFUs, which required the fabrication of an unprecedented 1152 optical surfaces, the CfAI have demonstrated that they have the capacity to produce the required volume within reasonable schedule constraints. All the facilities (design, fabrication e.g. diamond machining, metrology, integration and test) required for the successful realisation of such systems are available in-house, thus minimising programmatic risks. This paper presents the opto-mechanical design and predicted performance (based on the actual measured performance of the KMOS IFUs) of the proposed metal IFU.

  15. VANET Routing Protocols: Pros and Cons

    OpenAIRE

    Paul, Bijan; Ibrahim, Md.; Bikas, Md. Abu Naser

    2012-01-01

    VANET (Vehicular Ad-hoc Network) is a new technology which has taken enormous attention in the recent years. Due to rapid topology changing and frequent disconnection makes it difficult to design an efficient routing protocol for routing data among vehicles, called V2V or vehicle to vehicle communication and vehicle to road side infrastructure, called V2I. The existing routing protocols for VANET are not efficient to meet every traffic scenarios. Thus design of an efficient routing protocol h...

  16. Development of an alternative route for recycling AA2050 aluminum alloy by powder metallurgy; Desenvolvimento de uma rota alternativa para reciclagem da liga de aluminio AA2050 via metalurgia do po

    Energy Technology Data Exchange (ETDEWEB)

    Guido, V.; Oliveira, A.C. de; Travessa, D.N.; Cardoso, K.R., E-mail: vane.guid@gmail.com [Universidade Federal de Sao Paulo (USP), Sao Jose dos Campos, SP (Brazil). Instituto de Ciencia e Tecnologia

    2014-07-01

    This paper presents an alternative solid state route to recycling AA2050 aeronautical aluminium alloy chips. The first stage in the recycling process, reported in this work, is the obtainment of the alloy powder by high energy ball milling to subsequent cold pressing and hot extrusion. The process started with the cleaning of chips with the aim of contaminant removing from machining process and transport, followed by the high energy ball milling to result in the AA2050 alloy powder. The powder obtained was characterized by laser size particle analysis, scanning electron microscopy (SEM), X-Ray diffraction (DRX) and inductively coupled plasma atomic emission spectroscopy (ICP-AES). The results show the feasibility of obtaining a powder having appropriate particle size and chemical composition in accordance with the specification for alloy. (author)

  17. Alternative routes to the leader male role in a multi-level society: follower vs. solitary male strategies and outcomes in hamadryas baboons.

    Science.gov (United States)

    Pines, Mathew; Saunders, Julian; Swedell, Larissa

    2011-07-01

    The nested one-male units (OMUs) of the hamadryas baboon are part of a complex social system in which "leader" males achieve near exclusive mating access by forcibly herding females into permanent consortships. Within this multi-level social system (troops, bands, clans and OMUs) are two types of prereproductive males--the follower and solitary male--whose different trajectories converge on the leader role. Here we compare OMU formation strategies of followers, who associate with a particular OMU and may have social access to females, with those of solitary males, who move freely within the band and do not associate regularly with OMUs. Data were derived from 42 OMU formations (16 by followers and 26 by solitary males) occurring over 8 years in a hamadryas baboon band at the Filoha site in Ethiopia. "Initial units" (IUs) with sexually immature females (IU strategy) were formed by 44% of followers and 46% of solitary males. The remaining followers took over mature females when their leader was deposed (challenge strategy) or disappeared (opportunistic strategy), or via a seemingly peaceful transfer (inheritance strategy). Solitary males took over mature females from other clans and bands, but mainly from old, injured or vanished leaders within their clan (via both the challenge and opportunistic strategies). Former followers of an OMU were more successful at taking over females from those OMUs than any other category of male. Despite this advantage enjoyed by ex-follower leaders, ex-solitary leaders were equally capable of increasing their OMU size at a comparable rate in their first 2 years as a leader. These results demonstrate the potential for males to employ both multiple roles (follower vs. solitary male) and multiple routes (IU, inheritance, challenge, opportunistic) to acquire females and become a leader male in a mating system characterized by female defense polygyny in a competitive arena. © 2011 Wiley-Liss, Inc.

  18. Randomized controlled trials and neuro-oncology: should alternative designs be considered?

    Science.gov (United States)

    Mansouri, Alireza; Shin, Samuel; Cooper, Benjamin; Srivastava, Archita; Bhandari, Mohit; Kondziolka, Douglas

    2015-09-01

    quality of design/reporting of RCTs in neuro-oncology persist. Quality improvement is necessary. Consideration of alternative strategies should be considered.

  19. Preliminary study for alternative conceptual core design of the MTR research reactor

    Science.gov (United States)

    Surbakti, T.; Pinem, S.; Sembiring, T. M.; Subekti, M.; Sunaryo, G. R.

    2018-02-01

    The utilization of the research reactor is increasingly widespread, especially for radioisotope production and testing of advanced materials and preference to use a compact core. The reactor core design has been determined on the maximum thermal flux in the middle of the core per MW. BATAN has designed several alternative research reactor cores. The purpose of this research reactor is to obtain the optimum reactor core configurations with the criteria to have a thermal neutron flux in the centre of the core with minimum of 1.0×1015 n/cm2 s. Power level of the research reactor is 60 MWthwith U9Mo/Al fuel 85 cm of height. Design of plate-type fuels with a higher core results in the heat transfer to the coolant optimal. All 16 fuel assemblies and the 4 control rodsare inserted into the core for this reactor. The core design calculations were carried out with the WIMSD-5B and BATAN-FUEL codes. Conceptual design calculation results show that the core configuration with 5 × 5 grids, all the fresh fuel, fuel loading of 470 g, a D2O reflector, a maximum thermal neutron flux in the central core is 1.09 x 1015 n/cm2s and the cycle length is 33 days. The reactor core design is the most optimal for MTR type. For the equilibrium core, a fuel loading of 600 g results in the maximum thermal flux of 1.07x1015 n/cm2s and the two safety rods should be used in the core.

  20. A note on “An alternative multiple attribute decision making methodology for solving optimal facility layout design selection problems”

    OpenAIRE

    R. Venkata Rao

    2012-01-01

    A paper published by Maniya and Bhatt (2011) (An alternative multiple attribute decision making methodology for solving optimal facility layout design selection problems, Computers & Industrial Engineering, 61, 542-549) proposed an alternative multiple attribute decision making method named as “Preference Selection Index (PSI) method” for selection of an optimal facility layout design. The authors had claimed that the method was logical and more appropriate and the method gives directly the o...

  1. Improving routing efficiency through intermediate target based geographic routing

    Directory of Open Access Journals (Sweden)

    Zongming Fei

    2015-08-01

    Full Text Available The greedy strategy of geographical routing may cause the local minimum problem when there is a hole in the routing area. It depends on other strategies such as perimeter routing to find a detour path, which can be long and result in inefficiency of the routing protocol. In this paper, we propose a new approach called Intermediate Target based Geographic Routing (ITGR to solve the long detour path problem. The basic idea is to use previous experience to determine the destination areas that are shaded by the holes. The novelty of the approach is that a single forwarding path can be used to determine a shaded area that may cover many destination nodes. We design an efficient method for the source to find out whether a destination node belongs to a shaded area. The source then selects an intermediate node as the tentative target and greedily forwards packets to it, which in turn forwards the packet to the final destination by greedy routing. ITGR can combine multiple shaded areas to improve the efficiency of representation and routing. We perform simulations and demonstrate that ITGR significantly reduces the routing path length, compared with existing geographic routing protocols.

  2. RIP Input From WAPDEG for LA Desgin Selection: Enhanced Design Alternative II

    Energy Technology Data Exchange (ETDEWEB)

    B.E. Bullard

    1999-07-16

    The purpose of this analysis is to identify and analyze concepts for the acquisition of data in support of the Performance Confirmation (PC) program at the potential subsurface nuclear waste repository at Yucca Mountain. This analysis is being prepared to document an investigation of design concepts, current available technology, technology trends, and technical issues associated with data acquisition during the PC period. This analysis utilizes the ''Performance Confirmation Plan'' (CRWMS M&O 2000b) to help define the scope for the PC data acquisition system. The focus of this analysis is primarily on the PC period for a minimum of 30 years after emplacement of the last waste package. The design of the data acquisition system shall allow for a closure deferral up to 300 years from initiation of waste emplacement. (CRWMS M&O 2000h, page 5-1). This analysis is a revision to and supercedes analysis, ''Performance Confirmation Data Acquisition System'', DI No. BCAI00000-017 17-0200-00002 Rev 00 (CRWMS M&O 1997), and incorporates the latest repository design changes following the M&O & DOE evaluation of a series of Enhanced Design Alternatives (EDAs), as described in the ''Enhanced Design Alternatives II Report'' (CRWMS M&O 1999d). Significant design changes include: thermal line loading of the emplacement drifts, closer spacing of the waste packages (WPs), wider spacing and fewer emplacement drifts, continuous ventilation of all active emplacement drifts, thinner walled WP designs which will increase external radiation levels, a 50-year repository closure option, inclusion of a drip-shield, exclusion of backfill, and new conceptual designs for the waste emplacement vehicles and equipment (Stroupe 2000). The scope and primary objectives of this analysis are to: (1) Review the criteria for design as presented in the Performance Confirmation Data Acquisition/Monitoring System Description Document, by way of the

  3. Intersecting Knowledge Fields and Integrating Data-Driven Computational Design en Route to Performance-Oriented and Intensely Local Architectures

    Directory of Open Access Journals (Sweden)

    Michael U Hensel

    2014-11-01

    Full Text Available This paper discusses research by design efforts in architectural education, focused on developing concepts and methods for the design of performance-oriented and intensely local architectures. The pursued notion of performance foregrounds the interaction between a given architecture and its local setting, with consequences not only for the design product but also for the related processes by which it is generated. Integrated approaches to data-driven computational design serve to generate such designs. The outlined approach shifts the focus of design attention away from the delivery of finite architectural objects and towards an expanded range of architecture-environment interactions that are registered, instrumentalised and modulated over time. This paper examines ongoing efforts in integrating specific architectural goals and approaches, computational data-driven design methods and generative design processes, based on a range of context-specific and often real-time data sets. The work discussed is produced in the context of the Research Centre for Architecture and Tectonics (RCAT and the Advanced Computational Design Laboratory (ACDL at the Oslo School of Architecture and Design.

  4. Preliminary Evaluation of Alternate Designs for HFIR Low-Enriched Uranium Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Renfro, David G [ORNL; Chandler, David [ORNL; Cook, David Howard [ORNL; Ilas, Germina [ORNL; Jain, Prashant K [ORNL; Valentine, Jennifer R [ORNL

    2014-11-01

    Engineering design studies of the feasibility of conversion of the High Flux Isotope Reactor (HFIR) from high-enriched uranium (HEU) to low-enriched uranium (LEU) fuel are ongoing at Oak Ridge National Laboratory (ORNL) as part of an effort sponsored by the U.S. Department of Energy s Global Threat Reduction Initiative (GTRI)/Reduced Enrichment for Research and Test Reactors (RERTR) program. The fuel type selected by the program for the conversion of the five high-power research reactors in the U.S. that still use HEU fuel is a new U-Mo monolithic fuel. Studies by ORNL have previously indicated that HFIR can be successfully converted using the new fuel provided (1) the reactor power can be increased from 85 MW to 100 MW and (2) the fuel can be fabricated to a specific reference design. Fabrication techniques for the new fuel are under development by the program but are still immature, especially for the complex aspects of the HFIR fuel design. In FY 2012, the program underwent a major shift in focus to emphasize developing and qualifying processes for the fabrication of reliable and affordable LEU fuel. In support of this new focus and in an effort to ensure that the HFIR fuel design is as suitable for reliable fabrication as possible, ORNL undertook the present study to propose and evaluate several alternative design features. These features include (1) eliminating the fuel zone axial contouring in the previous reference design by substituting a permanent neutron absorber in the lower unfueled region of all of the fuel plates, (2) relocating the burnable neutron absorber from the fuel plates of the inner fuel element to the side plates of the inner fuel element (the fuel plates of the outer fuel element do not contain a burnable absorber), (3) relocating the fuel zone inside the fuel plate to be centered on the centerline of the depth of the plate, and (4) reshaping the radial contour of the relocated fuel zone to be symmetric about this centerline. The present

  5. Preliminary Evaluation of Alternate Designs for HFIR Low-Enriched Uranium Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Renfro, David [ORNL; Chandler, David [ORNL; Cook, David [ORNL; Ilas, Germina [ORNL; Jain, Prashant [ORNL; Valentine, Jennifer [ORNL

    2014-10-30

    Engineering design studies of the feasibility of conversion of the High Flux Isotope Reactor (HFIR) from high-enriched uranium (HEU) to low-enriched uranium (LEU) fuel are ongoing at Oak Ridge National Laboratory (ORNL) as part of an effort sponsored by the U.S. Department of Energy’s Global Threat Reduction Initiative (GTRI)/Reduced Enrichment for Research and Test Reactors (RERTR) program. The fuel type selected by the program for the conversion of the five high-power research reactors in the U.S. that still use HEU fuel is a new U-Mo monolithic fuel. Studies by ORNL have previously indicated that HFIR can be successfully converted using the new fuel provided (1) the reactor power can be increased from 85 MW to 100 MW and (2) the fuel can be fabricated to a specific reference design. Fabrication techniques for the new fuel are under development by the program but are still immature, especially for the “complex” aspects of the HFIR fuel design. In FY 2012, the program underwent a major shift in focus to emphasize developing and qualifying processes for the fabrication of reliable and affordable LEU fuel. In support of this new focus and in an effort to ensure that the HFIR fuel design is as suitable for reliable fabrication as possible, ORNL undertook the present study to propose and evaluate several alternative design features. These features include (1) eliminating the fuel zone axial contouring in the previous reference design by substituting a permanent neutron absorber in the lower unfueled region of all of the fuel plates, (2) relocating the burnable neutron absorber from the fuel plates of the inner fuel element to the side plates of the inner fuel element (the fuel plates of the outer fuel element do not contain a burnable absorber), (3) relocating the fuel zone inside the fuel plate to be centered on the centerline of the depth of the plate, and (4) reshaping the radial contour of the relocated fuel zone to be symmetric about this centerline. The

  6. BIM Application to Select Appropriate Design Alternative with Consideration of LCA and LCCA

    Directory of Open Access Journals (Sweden)

    Young-su Shin

    2015-01-01

    Full Text Available Advancements in building materials and technology have led to the rapid development of various design solutions. At the same time, life cycle assessment (LCA and life cycle cost analysis (LCCA of such solutions have become a great burden to engineers and project managers. To help conduct LCA and LCCA conveniently, this study (i analyzed the information needed to conduct LCA and LCCA, (ii evaluated a way to obtain such information in an easy and accurate manner using a building information modeling tool, and (iii developed an Excel spreadsheet-based framework that allowed for the simultaneous implementation of LCA and LCCA. The framework developed for LCA and LCCA was applied to a real building case to evaluate three possible alternatives for an external skin system. The framework could easily and accurately determine which skin system had good properties in terms of the LCA and LCCA performance. Therefore, these results are expected to assist in decision making based on the perspectives of economic and environmental performances in the early phases of a project, where various alternatives can be created and evaluated.

  7. User-Centered Design and Augmentative and Alternative Communication Apps for Children With Autism Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    Margaret Lubas

    2014-05-01

    Full Text Available Communication difficulties are among the most frequent characteristics of children with autism spectrum disorders (ASD. Lack of communication can have a significant impact on the child’s life. Augmentative and alternative communication (AAC apps are a common form of AAC interventions that involve a combination of affordable technology with software that can be utilized to assist with communication. While AAC apps have been found to have some impact on improving the communication skills of children with ASD, current research exploring this topic is still limited. Focusing on the design process of AAC apps may provide better insight into improving clinical outcomes and user success. The user-centered design process incorporates a continuous cycle of user feedback to help inform and improve the functions and the capabilities of the technology, and it is an essential component in AAC app development. This article outlines how the user-centered design process could be adopted for the development of AAC apps for children with ASD.

  8. Implementing a method of screening one-well hydraulic barrier design alternatives.

    Science.gov (United States)

    Rubin, Hillel; Shoemaker, Christine A; Köngeter, Jürgen

    2009-01-01

    This article provides details of applying the method developed by the authors (Rubin et al. 2008b) for screening one-well hydraulic barrier design alternatives. The present article with its supporting information (manual and electronic spreadsheets with a case history example) provides the reader complete details and examples of solving the set of nonlinear equations developed by Rubin et al. (2008b). It allows proper use of the analytical solutions and also depicting the various charts given by Rubin et al. (2008b). The final outputs of the calculations are the required position and the discharge of the pumping well. If the contaminant source is nonaqueous phase liquid (NAPL) entrapped within the aquifer, then the method provides an estimate of the aquifer remediation progress (which is a by-product) due to operating the hydraulic barrier.

  9. Experimental analysis of stereotypy with applications of nonparametric statistical tests for alternating treatments designs.

    Science.gov (United States)

    Lloyd, Blair P; Finley, Crystal I; Weaver, Emily S

    2015-11-17

    Stereotypy is common in individuals with developmental disabilities and may become disruptive in the context of instruction. The purpose of this study was to embed brief experimental analyses in the context of reading instruction to evaluate effects of antecedent and consequent variables on latencies to and durations of stereotypy. We trained a reading instructor to implement a trial-based functional analysis and a subsequent antecedent analysis of stimulus features for an adolescent with autism in a reading clinic. We used alternating treatments designs with applications of nonparametric statistical analyses to control Type I error rates. Results of the experimental analyses suggested stereotypy was maintained by nonsocial reinforcement and informed the extent to which features of academic materials influenced levels of stereotypy. Results of nonparametric statistical analyses were consistent with conclusions based on visual analysis. Brief experimental analyses may be embedded in academic instruction to inform the stimulus conditions that influence stereotypy.

  10. Designing Alternative Transport Methods for the Distributed Data Collection of ATLAS EventIndex Project

    CERN Document Server

    Fernandez Casani, Alvaro; The ATLAS collaboration

    2016-01-01

    One of the key and challenging tasks of the ATLAS EventIndex project is to index and catalog all the produced events not only at CERN but also at hundreds of worldwide grid sites, and convey the data in real time to a central Hadoop instance at CERN. While this distributed data collection is currently operating correctly in production, there are some issues that might impose performance bottlenecks in the future, with an expected rise in the event production and reprocessing rates. In this work, we first describe the current approach based on a messaging system, which conveys the data from the sources to the central catalog, and we identify some weaknesses of this system. Then, we study a promising alternative transport method based on an object store, presenting a performance comparison with the current approach, and the architectural design changes needed to adapt the system to the next run of the ATLAS experiment at CERN.

  11. Relative risk measure suitable for comparison of design alternatives of interim spent nuclear fuel storage facility

    International Nuclear Information System (INIS)

    Ferjencik, M.

    1997-01-01

    Accessible reports on risk assessment of interim spent nuclear fuel storage facilities presume that only releases of radioactive substances represent undesired consequences. However, only certain part of the undesired consequences is represented by them. Many other events are connected with safety and are able to cause losses to the operating company. The following two presumptions are pronounced based on this. 1. Any event causing a disturbance of a safety function of the storage facility is an incident event. 2. Any disturbance of a safety function is an undesired consequence. If the facility safety functions are identified and if the severity of their disturbances is quantified, then it is possible to combine consequence severity quantifications and event frequencies into a risk measure. Construction and application of such a risk measure is described in this paper. The measure is shown to be a tool suitable for comparison of interim storage technology design alternatives. (author)

  12. Composting on Mars or the Moon: I. Comparative evaluation of process design alternatives

    Science.gov (United States)

    Finstein, M. S.; Strom, P. F.; Hogan, J. A.; Cowan, R. M.; Janes, H. W. (Principal Investigator)

    1999-01-01

    As a candidate technology for treating solid wastes and recovering resources in bioregenerative Advanced Life Support, composting potentially offers such advantages as compactness, low mass, near ambient reactor temperatures and pressures, reliability, flexibility, simplicity, and forgiveness of operational error or neglect. Importantly, the interactions among the physical, chemical, and biological factors that govern composting system behavior are well understood. This article comparatively evaluates five Generic Systems that describe the basic alternatives to composting facility design and control. These are: 1) passive aeration; 2) passive aeration abetted by mechanical agitation; 3) forced aeration--O2 feedback control; 4) forced aeration--temperature feedback control; 5) forced aeration--integrated O2 and temperature feedback control. Each of the five has a distinctive pattern of behavior and process performance characteristics. Only Systems 4 and 5 are judged to be viable candidates for ALS on alien worlds, though which is better suited in this application is yet to be determined.

  13. DESIGN AND DEVELOPMENT OF AUGMENTATIVE AND ALTERNATIVE DIGITAL HOME CONTROL INTERFACE

    Directory of Open Access Journals (Sweden)

    Matteo Pastorino

    2013-05-01

    Full Text Available An inquiry of the National Statistics Institute of Spain shows that 74% of the Spanish population with disabilities suffers some kind of limitation performing Daily Basic Activities, while 1.39 million cannot perform them at all without the assistance of specialized personnel. Digital Home Systems could mitigate disabled people’s difficulties to carry out those activities, giving the opportunity to manage home appliances through a single control. Digital Home Systems have to provide specific and adapted control interfaces based on Augmentative and Alternative Communication languages in order to be an efficient solution to the problem and to allow most vulnerable groups of people with disabilities to reach the highest level of autonomy.  This paper describes a Digital Home Interface capable of adapting layouts, styles and contents to device capability, user preferences and appliances’ features; designed with a combination of web technologies, standard languages for abstract interface definition and AAC systems.

  14. Perfil de pacientes em uso de via alternativa de alimentação internados em um hospital geral Profile of patients using alternative feeding route in a general hospital

    Directory of Open Access Journals (Sweden)

    Serjana Cavalcante Jucá Nogueira

    2013-02-01

    Full Text Available OBJETIVO: caracterizar a população em uso de via alternativa de alimentação internada em um hospital geral de referência. MÉTODO: estudo transversal prospectivo, tendo-se realizado coleta de dados em 229 prontuários de pacientes em uso de via alternativa de alimentação internados em enfermarias adultas de um hospital geral, identificando-se dados referentes à via alternativa de alimentação em uso, justificativas clínicas, doença(s de base e demais aspectos clínicos relacionados aos distúrbios de deglutição. RESULTADOS: houve predomínio do sexo masculino (55,02%; 70,3% dos pacientes apresentaram diagnóstico de alguma doença neurológica e a via de alimentação mais utilizada foi a sonda nasoenteral (82,53%. Embora a pneumonia e a desnutrição tenham sido diagnosticadas na minoria dos casos (35,08% e 10,04%, houve associação entre as variáveis pneumonia e disfagia (p=0,0098, não ocorrendo o mesmo entre desnutrição e disfagia (p=0,0759. A disfagia foi citada em apenas em 6,55% dos casos. Observou-se, ainda, alta frequência de ausência de dados referente aos sinais e sintomas de dificuldade de alimentação e de justificativas para indicação da via alternativa de alimentação prescrita. CONCLUSÃO: embora a população estudada tenha apresentado fatores de risco para desenvolvimento de distúrbios da deglutição, como doenças de base com alta ocorrência de disfagia e alteração do nível de consciência e/ou sonolência, a baixa frequência do diagnóstico da disfagia e a constante falta de dados relacionados ao contexto alimentar revelaram a pouca importância dada às manifestações funcionais pela unidade hospitalar estudada.PURPOSE: to characterize the population submitted to administration of alternative feeding route admitted to a general hospital in the state of Alagoas. METHOD: data from medical records of 229 patients admitted to adult infirmary were investigated. Data referring to the administration

  15. On routing strategy with finite-capacity effect on scale-free networks

    International Nuclear Information System (INIS)

    Tang, S.; Jiang, X.; Ma, L.; Zhang, Z.; Zheng, Z.

    2010-01-01

    We propose a class of systems with finite-capacity effect to investigate routing-strategy optimization. The local topology and the variable capacity, two crucial elements for routing, are naturally coupled by considering the interactions among packets. We show how the combination of these two elements controls the normal and efficient functioning of routing in the frame of condensation and coverage, respectively. Specifically, it is shown that the dynamic behaviors of diffusing packets exhibit condensation, for which exact results of the stationary state and phase transition are given. Further, we explore the diffusion coverage of routed packets through simulation. Various alternatives for the strategy parameters are illustrated to apply standard techniques to alleviate condensation and accelerate coverage. Our results provide a practical way for the design of optimal routing strategies in complex networks by the manipulation of a few parameters. (author)

  16. Greenhouse gas emissions of alternative pavement designs: framework development and illustrative application.

    Science.gov (United States)

    Liu, Xiaoyu; Cui, Qingbin; Schwartz, Charles

    2014-01-01

    Pavement rehabilitation is carbon intensive and the choice of pavement type is a critical factor in controlling greenhouse gas (GHG) emissions. The existing body of knowledge is not able to support decision-making on pavement choice due to a lack of consensus on the system boundaries, the functional units and the estimation periods. Excessive data requirements further inhibit the generalization of the existing methodologies for design evaluation at the early planning stage. This study proposes a practical life-cycle GHG estimation approach, which is arguably effective to benchmark pavement emissions given project bid tabulation. A set of case studies conducted for this study suggest that recycled asphalt pavement (e.g., foam stabilized base (FSB), and warm mix asphalt (WMA)) would prevent up to 50% of GHGs from the initial construction phase. However, from a life-cycle perspective, pavement emissions are dictated largely by the traffic characteristics and the analysis period for the use phase. The benefits from using recycled materials (e.g., FSB) are likely to diminish if the recycled products do not perform as well as those properly proportioned with less recycled materials, or if the recycled materials are locally unavailable. When the AADT reaches 10,000, use phase releases more than 97% of the life cycle emissions and the emissions difference among alternative designs will be within 1%. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Hadron cancer therapy complex using nonscaling fixed field alternating gradient accelerator and gantry design

    Directory of Open Access Journals (Sweden)

    E. Keil

    2007-05-01

    Full Text Available Nonscaling fixed field alternating gradient (FFAG rings for cancer hadron therapy offer reduced physical aperture and large dynamic aperture as compared to scaling FFAGs. The variation of tune with energy implies the crossing of resonances during acceleration. Our design avoids intrinsic resonances, although imperfection resonances must be crossed. We consider a system of three nonscaling FFAG rings for cancer therapy with 250 MeV protons and 400   MeV/u carbon ions. Hadrons are accelerated in a common radio frequency quadrupole and linear accelerator, and injected into the FFAG rings at v/c=0.1294. H^{+}/C^{6+} ions are accelerated in the two smaller/larger rings to 31 and 250  MeV/68.8 and 400   MeV/u kinetic energy, respectively. The lattices consist of doublet cells with a straight section for rf cavities. The gantry with triplet cells accepts the whole required momentum range at fixed field. This unique design uses either high-temperature superconductors or superconducting magnets reducing gantry magnet size and weight. Elements with a variable field at the beginning and at the end set the extracted beam at the correct position for a range of energies.

  18. Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5'-Phosphate Production in E. coli.

    Directory of Open Access Journals (Sweden)

    Matthew A Oberhardt

    2016-01-01

    Full Text Available Recent insights suggest that non-specific and/or promiscuous enzymes are common and active across life. Understanding the role of such enzymes is an important open question in biology. Here we develop a genome-wide method, PROPER, that uses a permissive PSI-BLAST approach to predict promiscuous activities of metabolic genes. Enzyme promiscuity is typically studied experimentally using multicopy suppression, in which over-expression of a promiscuous 'replacer' gene rescues lethality caused by inactivation of a 'target' gene. We use PROPER to predict multicopy suppression in Escherichia coli, achieving highly significant overlap with published cases (hypergeometric p = 4.4e-13. We then validate three novel predicted target-replacer gene pairs in new multicopy suppression experiments. We next go beyond PROPER and develop a network-based approach, GEM-PROPER, that integrates PROPER with genome-scale metabolic modeling to predict promiscuous replacements via alternative metabolic pathways. GEM-PROPER predicts a new indirect replacer (thiG for an essential enzyme (pdxB in production of pyridoxal 5'-phosphate (the active form of Vitamin B6, which we validate experimentally via multicopy suppression. We perform a structural analysis of thiG to determine its potential promiscuous active site, which we validate experimentally by inactivating the pertaining residues and showing a loss of replacer activity. Thus, this study is a successful example where a computational investigation leads to a network-based identification of an indirect promiscuous replacement of a key metabolic enzyme, which would have been extremely difficult to identify directly.

  19. Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5’-Phosphate Production in E. coli

    Science.gov (United States)

    Reshef, Leah; Xia, Fangfang; Duran-Frigola, Miquel; Schreiber, Rachel; Henry, Christopher S.; Ben-Tal, Nir; Dwyer, Daniel J.; Gophna, Uri; Ruppin, Eytan

    2016-01-01

    Recent insights suggest that non-specific and/or promiscuous enzymes are common and active across life. Understanding the role of such enzymes is an important open question in biology. Here we develop a genome-wide method, PROPER, that uses a permissive PSI-BLAST approach to predict promiscuous activities of metabolic genes. Enzyme promiscuity is typically studied experimentally using multicopy suppression, in which over-expression of a promiscuous ‘replacer’ gene rescues lethality caused by inactivation of a ‘target’ gene. We use PROPER to predict multicopy suppression in Escherichia coli, achieving highly significant overlap with published cases (hypergeometric p = 4.4e-13). We then validate three novel predicted target-replacer gene pairs in new multicopy suppression experiments. We next go beyond PROPER and develop a network-based approach, GEM-PROPER, that integrates PROPER with genome-scale metabolic modeling to predict promiscuous replacements via alternative metabolic pathways. GEM-PROPER predicts a new indirect replacer (thiG) for an essential enzyme (pdxB) in production of pyridoxal 5’-phosphate (the active form of Vitamin B6), which we validate experimentally via multicopy suppression. We perform a structural analysis of thiG to determine its potential promiscuous active site, which we validate experimentally by inactivating the pertaining residues and showing a loss of replacer activity. Thus, this study is a successful example where a computational investigation leads to a network-based identification of an indirect promiscuous replacement of a key metabolic enzyme, which would have been extremely difficult to identify directly. PMID:26821166

  20. Whirlpool routing for mobility

    KAUST Repository

    Lee, Jung Woo

    2010-01-01

    We present the Whirlpool Routing Protocol (WARP), which efficiently routes data to a node moving within a static mesh. The key insight in WARP\\'s design is that data traffic can use an existing routing gradient to efficiently probe the topology, repair the routing gradient, and communicate these repairs to nearby nodes. Using simulation, controlled testbeds, and real mobility experiments, we find that using the data plane for topology maintenance is highly effective due to the incremental nature of mobility updates. WARP leverages the fact that converging flows at a destination make the destination have the region of highest traffic. We provide a theoretical basis for WARP\\'s behavior, defining an "update area" in which the topology must adjust when a destination moves. As long as packets arrive at a destination before it moves outside of the update area, WARP can repair the topology using the data plane. Compared to existing protocols, such as DYMO and HYPER, WARP\\'s packet drop rate is up to 90% lower while sending up to 90% fewer packets.

  1. Analytical design of a parasitic-loading digital speed controller for a 400-hertz turbine driven alternator

    Science.gov (United States)

    Ingle, B. D.; Ryan, J. P.

    1972-01-01

    A design for a solid-state parasitic speed controller using digital logic was analyzed. Parasitic speed controllers are used in space power electrical generating systems to control the speed of turbine-driven alternators within specified limits. The analysis included the performance characteristics of the speed controller and the generation of timing functions. The speed controller using digital logic applies step loads to the alternator. The step loads conduct for a full half wave starting at either zero or 180 electrical degrees.

  2. Using pilot test data to refine an alternative cover design in northern California.

    Science.gov (United States)

    Smesrud, Jason K; Benson, Craig H; Albright, William H; Richards, James H; Wright, Shannon; Israel, Tim; Goodrich, Keith

    2012-01-01

    Two instrumented test sections were constructed in summer 1999 at the Kiefer Landfill near Sacramento, California to test the hydraulic performance of two proposed alternative final covers. Both test sections simulated monolithic evapotranspiration (ET) designs that differed primarily in thickness. Both were seeded with a mix of two perennial and one annual grass species. Oleander seedlings were also planted in the thicker test section. Detailed hydrologic performance monitoring of the covers was conducted from 1999 through 2005, The thicker test section met the performance criterion (average percolation of percolation (average of 55 mm/y). Both test sections were decommissioned in summer 2005 to investigate changes in soil hydraulic properties, geomorphology, and vegetation and to collect data to support a revised design. Field data from hydrologic monitoring and the decommissioning study were subsequently included in a hydrologic modeling study to estimate the performance of an optimized cover system for full-scale application. The decommissioning study showed that properties of the soils changed over the monitoring period (saturated hydraulic conductivity and water holding capacity increased, density decreased) and that the perennial grasses and shrubs intended for the cover were out-competed by annual species with shallower roots and lesser capacity for water uptake. Of these changes, reduced ET from the shallow-rooted annual vegetation is believed to be the primary cause for the high percolation rate from the thinner test section. Hydrologic modeling suggests that the target hydraulic performance can be achieved using an ET cover with similar thickness to the thin test section if perennial vegetation species observed in surrounding grasslands can be established. This finding underscores the importance of establishing and maintaining the appropriate vegetation on ET covers in this climate.

  3. Properties of alternative microbial hosts used in synthetic biology: towards the design of a modular chassis

    Science.gov (United States)

    Kim, Juhyun; Salvador, Manuel; Saunders, Elizabeth; González, Jaime; Avignone-Rossa, Claudio

    2016-01-01

    The chassis is the cellular host used as a recipient of engineered biological systems in synthetic biology. They are required to propagate the genetic information and to express the genes encoded in it. Despite being an essential element for the appropriate function of genetic circuits, the chassis is rarely considered in their design phase. Consequently, the circuits are transferred to model organisms commonly used in the laboratory, such as Escherichia coli, that may be suboptimal for a required function. In this review, we discuss some of the properties desirable in a versatile chassis and summarize some examples of alternative hosts for synthetic biology amenable for engineering. These properties include a suitable life style, a robust cell wall, good knowledge of its regulatory network as well as of the interplay of the host components with the exogenous circuits, and the possibility of developing whole-cell models and tuneable metabolic fluxes that could allow a better distribution of cellular resources (metabolites, ATP, nucleotides, amino acids, transcriptional and translational machinery). We highlight Pseudomonas putida, widely used in many different biotechnological applications as a prominent organism for synthetic biology due to its metabolic diversity, robustness and ease of manipulation. PMID:27903818

  4. Methodology for the nuclear design validation of an Alternate Emergency Management Centre (CAGE)

    International Nuclear Information System (INIS)

    Hueso, C.; De La Fuente, C.; Janes, A.; Massuet, J.; Zamora, I.; Fabbri, M.; Gasca, C.; Hernandez, H.; Angel Vega, J.

    2017-01-01

    As a consequence of the Fukushima accident, Spanish nuclear authorities have decided to equip each nuclear power plant with an Alternate Emergency Management Centre (CAGE) that will manage safely any emergency occurring on the site. The living conditions of the occupants of the CAGE in the event of a Severe Accident imply that TEDE (Total Effective Dose Equivalent) must be<50 mSv and the equivalent dose to the thyroid<500 mSv within 30 days following the accident. This paper presents the methodology followed to design CAGE in order to comply with above dose limits. The study of weather conditions as part of the data of the site will determine the relative concentrations of radionuclides in the air using ARCON96. The activity in the air is characterized depending on the source and release sequence specified in NUREG-1465 by RADTRAD code, which provides results of the inner cloud source term contribution. Known activities and energy spectra are inferred using ORIGEN-S, which are used as input for the models of the outer cloud, filters and containment generated with MCNP5. The sum of the different contributions must be below radiation dose limits. The radiation dose is optimized by varying parameters including CAGE location on the plant site, flow filtering need for recirculation, thicknesses and compositions of the walls, etc. The calculation codes selected for the development of this methodology are widely available, internationally used and validated in many studies

  5. On the failure modes of alternative containment designs following postulated core meltdown

    International Nuclear Information System (INIS)

    Chan, C.K.; Knee, H.E.; Okrent, D.

    1977-01-01

    The containment response to a postulated core meltdown accident in a PWR ice condenser containment, a BWR Mark III containment and a BWR non-inerted Mark I containment has been examined to see if the WASH-1400 containment failure mode judgement for the Surry large, dry containment and the Peach Bottom Mark I inerted-containment are likely to be appropriate for these alternative containment plant designs. For the PWR, the representative accident chosen for the analysis is a large cold leg break accompanied by a loss of all electric power while the BWR respresentative event chosen is a recirculation line break without adequate core cooling function. Two containment event paths are studied for each of these two cases, depending on whether or not containment vapor suppression function is assumed to be available. Both the core and the containment pressure and temperature response to the accident events are computed for the four time intervals which characterize (a) blowdown of the pipe break, (b) core melt, (c) vessel melt-through, and (d) containment foundation penetration. The calculations are based on a best esimate of the most probable sequence, but certain phenomena and events were followed down multiple tracks. It appears that the non-inerted Mark I containment is not so vulnerable to overpressurization from hydrogen burning as the Mark III; however, acceptable temperatures may be exceeded. (Auth.)

  6. Three-dimensional analysis of the Pratt and Whitney alternate design SSME fuel turbine

    Science.gov (United States)

    Kirtley, K. R.; Beach, T. A.; Adamczyk, J. J.

    1991-01-01

    The three dimensional viscous time-mean flow in the Pratt and Whitney alternate design space shuttle main engine fuel turbine is simulated using the average passage Navier-Stokes equations. The migration of secondary flows generated by upstream blade rows and their effect on the performance of downstream blade rows is studied. The present simulation confirms that the flow in this two stage turbine is highly three dimensional and dominated by the tip leakage flow. The tip leakage vortex generated by the first blade persists through the second blade and adversely affects its performance. The greatest mixing of the inlet total temperature distortion occurs in the second vane and is due to the large leakage vortex generated by the upstream rotor. It is assumed that the predominant spanwise mixing mechanism in this low aspect ratio turbine is the radial transport due to the deterministically unsteady vortical flow generated by upstream blade rows. A by-product of the analysis is accurate pressure and heat loads for all blade rows under the influence of neighboring blade rows. These aero loads are useful for advanced structural analysis of the vanes and blades.

  7. Catalytic acetoxylation of lactic acid to 2-acetoxypropionic acid, en route to acrylic acid

    NARCIS (Netherlands)

    Beerthuis, R.; Granollers, M.; Brown, D.R.; Salavagione, H.J.; Rothenberg, G.; Shiju, N.R.

    2015-01-01

    We present an alternative synthetic route to acrylic acid, starting from the platform chemical lactic acid and using heterogeneous catalysis. To improve selectivity, we designed an indirect dehydration reaction that proceeds via acetoxylation of lactic acid to 2-acetoxypropionic acid. This

  8. An analytic Study of the Key Factors In uencing the Design and Routing Techniques of a Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Yogita Bahuguna

    2017-03-01

    Full Text Available A wireless sensor network contains various nodes having certain sensing, processing and communication capabilities. Actually they are multifunctional battery operated nodes called motes. These motes are small in size and battery constrained. They are operated by a power source. A wireless sensor network consists of a huge number of tiny sensor nodes which are deployed either randomly or according to some predefined distribution. The sensors nodes in a sensor network are cooperative among themselves having self-organizing ability. This ensures that a wireless network serves a wide variety of applications. Few of them are weather monitoring, health, security and military etc. As their applications are wide, this requires that sensors in a sensor network must play their role very efficiently. But, as discussed above, the sensor nodes have energy limitation. This limitation leads failure of nodes after certain round of communication. So, a sensor network suffers with sensors having energy limitations. Beside this, sensor nodes in a sensor network must fulfill connectivity and coverage requirements. In this paper, we have discussed various issues affecting the design of a wireless sensor network. This provides the readers various research issues in designing a wireless sensor network.

  9. Synteny analysis provides a route to design genus-specific PCR primers for rapid identification of all Saccharomyces species.

    Science.gov (United States)

    Sharpe, Ben; Hulin, Michelle; Thorne-Wallis, James; Wheals, Alan

    2014-05-01

    The genus Saccharomyces comprises seven single-genome species (S. arboricola, S. cerevisiae, S. eubayanus, S. kudriavzevii, S. mikatae, S. paradoxus and S. uvarum) and two hybrid species - S. pastorianus (S. cerevisiae plus S. eubayanus) and S. bayanus (mostly S. uvarum plus S. eubayanus). Species-specific primers have already been developed for the identification of each of the single-genome species, and these primers can usually detect both genomes in hybrids. It would be advantageous if a single reaction could detect any member of the clade. We have investigated three potentially generic approaches to design genus-specific primers. Two methods that both use sequence alignment differences for primer design were only partly successful. A third method used synteny data to identify 136 target genes that are potentially present only in all species of the Saccharomyces clade. HSP30 (YCR021C) was fully successful; different primer pairs were developed with high G+C content for use at 63 °C. In genus. This novel approach still uses conventional sequence alignment mismatches but relies principally on the presence of the target gene only within the genus Saccharomyces. © 2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

  10. Snow route optimization.

    Science.gov (United States)

    2016-01-01

    Route optimization is a method of creating a set of winter highway treatment routes to meet a range of targets, including : service level improvements, resource reallocation and changes to overriding constraints. These routes will allow the : operato...

  11. Quality by design approach for formulation, evaluation and statistical optimization of diclofenac-loaded ethosomes via transdermal route.

    Science.gov (United States)

    Jain, Shashank; Patel, Niketkumar; Madan, Parshotam; Lin, Senshang

    2015-06-01

    The objective of this study was to fabricate and understand ethosomal formulations of diclofenac (DF) for enhanced anti-inflammatory activity using quality by design approach. DF-loaded ethosomal formulations were prepared using 4 × 5 full-factorial design with phosphatidylcholine:cholesterol (PC:CH) ratios ranging between 50:50 and 90:10, and ethanol concentration ranging between 0% and 30% as formulation variables. These formulations were characterized in terms of physicochemical properties and skin permeation kinetics. The interaction of formulation variables had a significant effect on both physicochemical properties and permeation kinetics. The results of multivariate regression analysis illustrated that vesicle size and elasticity of ethosomes were the dominating physicochemical properties affecting skin permeation, and could be suitably controlled by manipulation of formulation variables to optimize the formulation and enhance the skin permeation of DF-loaded ethosomes. The optimized formulation had ethanol concentration of 22.9% and PC:CH ratio of 88.4:11.6, with vesicle size of 144 ± 5 nm, zeta potential of -23.0 ± 3.76 mV, elasticity of 2.48 ± 0.75 and entrapment efficiency of 71 ± 4%. Permeation flux for the optimized formulation was 12.9 ± 1.0 µg/h cm(2), which was significantly higher than the drug-loaded conventional liposome, ethanolic or aqueous solution. The in vivo study indicated that optimized ethosomal hydrogel exhibited enhanced anti-inflammatory activity compared with liposomal and plain drug hydrogel formulations.

  12. An Energy-Efficient and Robust Multipath Routing Protocol for Cognitive Radio Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Kishor Singh

    2017-09-01

    Full Text Available Routing in cognitive radio ad hoc networks (CRAHNs is a daunting task owing to dynamic topology, intermittent connectivity, spectrum heterogeneity, and energy constraints. Other prominent aspects such as channel stability, path reliability, and route discovery frequency should also be exploited. Several routing protocols have been proposed for CRAHNs in the literature. By stressing on one of the aspects more than any other, however, they do not satisfy all requirements of throughput, energy efficiency, and robustness. In this paper, we propose an energy-efficient and robust multipath routing (ERMR protocol for CRAHNs by considering all prominent aspects including residual energy and channel stability in design. Even when the current routing path fails, the alternative routing path is immediately utilized. In establishing primary and alternative routing paths, both residual energy and channel stability are exploited simultaneously. Our simulation study shows that the proposed ERMR outperforms the conventional protocol in terms of network throughput, packet delivery ratio, energy consumption, and end-to-end delay.

  13. METHODOLOGY, ASSUMPTIONS, AND BASELINE DATA FOR THE REPOSITORY DESIGN AND OPERATION, RAIL CORRIDORS, AND HEAVY TRUCK ROUTES, CLARK COUNTY, NEVADA, LINCOLN COUNTY, NEVADA, NYE COUNTY, NEVADA, ''REST OF NEVADA'', STATE OF NEVADA

    International Nuclear Information System (INIS)

    2002-01-01

    This document was prepared in support of the ''Environmental Impact Statement for a Geologic Repository for the Disposal of Spent Nuclear Fuel and High-Level Radioactive Waste at Yucca Mountain; Nye County, Nevada''. Specifically, the document evaluates potential socioeconomic impacts resulting from the various rail corridor and heavy haul truck route implementing alternatives, one of which would be selected to transport the nation's commercial and defense spent nuclear fuel and high-level radioactive waste to the proposed repository

  14. Electro-Active Polymers (EAPs: A Promising Route to Design Bio-Organic/Bioinspired Platforms with on Demand Functionalities

    Directory of Open Access Journals (Sweden)

    Vincenzo Guarino

    2016-05-01

    Full Text Available Through recent discoveries and new knowledge among correlations between molecular biology and materials science, it is a growing interest to design new biomaterials able to interact—i.e., to influence, to guide or to detect—with cells and their surrounding microenvironments, in order to better control biological phenomena. In this context, electro-active polymers (EAPs are showing great promise as biomaterials acting as an interface between electronics and biology. This is ascribable to the highly tunability of chemical/physical properties which confer them different conductive properties for various applicative uses (i.e., molecular targeting, biosensors, biocompatible scaffolds. This review article is divided into three parts: the first one is an overview on EAPs to introduce basic conductivity mechanisms and their classification. The second one is focused on the description of most common processes used to manipulate EAPs in the form of two-dimensional (2D and three-dimensional (3D materials. The last part addresses their use in current applications in different biomedical research areas including tissue engineering, biosensors and molecular delivery.

  15. Alternatives for implementing burnup credit in the design and operation of spent fuel transport casks

    International Nuclear Information System (INIS)

    Sanders, T.L.; Lake, W.H.

    1989-01-01

    The traditional assumption used in evaluating criticality safety of spent fuel cask is that the spent fuel is as reactive as when it was fresh (new). This is known as the fresh fuel assumption. It avoids a number of calculational and verification difficulties, but could take a heavy toll in decreased efficiency. The alternative to the fresh fuel assumption is called burnup credit. That is, the reduced reactivity of spent fuel that comes about from depletion of fissile radionuclides and net increase in neutron absorbers (poisons) is taken into account. It is recognizable that the use of burnup credit will in fact increase the percentage of unacceptable or non-specification fuel available for misloading. This could reduce individual cask safety margins if current practices with respect to loading procedures are maintained. As such, additional operational, design, analysis, and validation requirements should be established that, as a minimum, compensate for any potential reduction in fuel loading safety margin. This method is based on a probabilistic (PRA) approach and is called a relative risk comparison. The method assumes a linear risk model, and uses a selected probability function to compare the system of interest and an acceptable reference system by varying the features of each to assess effects on system safety. While risk is the product of an event probability and its consequence, the consequences of criticality in a cask are considered to be both unacceptable and the same, regardless of the initiating sequence. Therefore, only the probability of the event is considered in a relative risk evaluation

  16. Parametric Optimization of Some Critical Operating System Functions--An Alternative Approach to the Study of Operating Systems Design

    Science.gov (United States)

    Sobh, Tarek M.; Tibrewal, Abhilasha

    2006-01-01

    Operating systems theory primarily concentrates on the optimal use of computing resources. This paper presents an alternative approach to teaching and studying operating systems design and concepts by way of parametrically optimizing critical operating system functions. Detailed examples of two critical operating systems functions using the…

  17. Treating Youths with Selective Mutism with an Alternating Design of Exposure-Based Practice and Contingency Management

    Science.gov (United States)

    Vecchio, Jennifer; Kearney, Christopher A.

    2009-01-01

    Selective mutism is a severe childhood disorder involving failure to speak in public situations in which speaking is expected. The present study examined 9 youths with selective mutism treated with child-focused, exposure-based practices and parent-focused contingency management via an alternating treatments design. Broadband measures of…

  18. Considerations for rigid vs. flexible pavement designs when allowed as alternate bids : technical report.

    Science.gov (United States)

    2009-08-01

    This report documents the research conducted for the Texas Department of Transportation (TxDOT) : concerning the use of pavement alternates. The scope of the project includes reviewing the state-of-thepractice : in methods used for pavement type sele...

  19. DESIGNING APPLICATION OF ANT COLONY SYSTEM ALGORITHM FOR THE SHORTEST ROUTE OF BANDA ACEH CITY AND ACEH BESAR REGENCY TOURISM BY USING GRAPHICAL USER INTERFACE MATLAB

    Directory of Open Access Journals (Sweden)

    Durisman Durisman

    2017-09-01

    Full Text Available Banda Aceh city and Aceh Besar Regency are two of the leading tourism areas located in the province of Aceh. For travelling, there are some important things to be considered, such as determining schedule and distance of tourism. Every tourist certainly chooses the shortest route to reach the destination since it can save time, energy, and money. The purpose of this reserach is to develop a method that can be used in calculating the shortest route and applied to the tourism of Banda Aceh city and Aceh Besar regency. In this reserach, Ant Colony Optimization algorithm is used to determine the shortest route to tourism of Banda Aceh city and Aceh Besar regency. From the analysis made by using both manual calculation and  GUI MATLAB program application test, the shortest route can be obtained with a minimum distance of 120.85 km in one travel. Based on the test result, the application for tourism (in Banda Aceh city and Aceh Besar regency shortest route searching built by utilizing the Ant Colony Optimization algorithm can find optimal route.  Keyword: tourism, the shortest route, Ant Colony Optimization

  20. Critical appraisal of arguments for the delayed-start design proposed as alternative to the parallel-group randomized clinical trial design in the field of rare disease.

    Science.gov (United States)

    Spineli, Loukia M; Jenz, Eva; Großhennig, Anika; Koch, Armin

    2017-08-17

    A number of papers have proposed or evaluated the delayed-start design as an alternative to the standard two-arm parallel group randomized clinical trial (RCT) design in the field of rare disease. However the discussion is felt to lack a sufficient degree of consideration devoted to the true virtues of the delayed start design and the implications either in terms of required sample-size, overall information, or interpretation of the estimate in the context of small populations. To evaluate whether there are real advantages of the delayed-start design particularly in terms of overall efficacy and sample size requirements as a proposed alternative to the standard parallel group RCT in the field of rare disease. We used a real-life example to compare the delayed-start design with the standard RCT in terms of sample size requirements. Then, based on three scenarios regarding the development of the treatment effect over time, the advantages, limitations and potential costs of the delayed-start design are discussed. We clarify that delayed-start design is not suitable for drugs that establish an immediate treatment effect, but for drugs with effects developing over time, instead. In addition, the sample size will always increase as an implication for a reduced time on placebo resulting in a decreased treatment effect. A number of papers have repeated well-known arguments to justify the delayed-start design as appropriate alternative to the standard parallel group RCT in the field of rare disease and do not discuss the specific needs of research methodology in this field. The main point is that a limited time on placebo will result in an underestimated treatment effect and, in consequence, in larger sample size requirements compared to those expected under a standard parallel-group design. This also impacts on benefit-risk assessment.

  1. Transportation of radioactive materials routing analysis: The Nevada experience

    International Nuclear Information System (INIS)

    Ardila-Coulson, M.V.

    1991-01-01

    In 1987, the Nevada State Legislature passed a Bill requiring the Nevada Dept. of Transportation to develop and enforce a plan for highway routing of highway route controlled quantity shipments of radioactive materials and high-level radioactive waste. A large network with all the major highways in Nevada was created and used in a computer model developed by Sandia National Labs. Twenty-eight highway parameters that included geometrics, traffic characteristics, environment and special facilities were collected. Alternative routes were identified by minimizing primary parameters (population density and accident rates). An analysis using the US DOT Guidelines were performed to identify a preferred route from the alternative routes

  2. Turbo-alternator-compressor design for supercritical high density working fluids

    Science.gov (United States)

    Wright, Steven A.; Fuller, Robert L.

    2013-03-19

    Techniques for generating power are provided. Such techniques involve a thermodynamic system including a housing, a turbine positioned in a turbine cavity of the housing, a compressor positioned in a compressor cavity of the housing, and an alternator positioned in a rotor cavity between the turbine and compressor cavities. The compressor has a high-pressure face facing an inlet of the compressor cavity and a low-pressure face on an opposite side thereof. The alternator has a rotor shaft operatively connected to the turbine and compressor, and is supported in the housing by bearings. Ridges extending from the low-pressure face of the compressor may be provided for balancing thrust across the compressor. Seals may be positioned about the alternator for selectively leaking fluid into the rotor cavity to reduce the temperature therein.

  3. Alternative Design Study Report: WindPACT Advanced Wind Turbine Drive Train Designs Study; November 1, 2000 -- February 28, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Poore, R.; Lettenmaier, T.

    2003-08-01

    This report presents the Phase I results of the National Renewable Energy Laboratory's (NREL's) WindPACT (Wind Partnership for Advanced Component Technologies) Advanced Wind Turbine Drive Train Designs Study. Global Energy Concepts, LLC performed this work under a subcontract with NREL. The purpose of the WindPACT project is to identify technology improvements that will enable the cost of energy (COE) from wind turbines to be reduced. Other parts of the WindPACT project have examined blade and logistics scaling, balance-of-station costs, and rotor design. This study was designed to investigate innovative drive train designs.

  4. Route assessment using comparative risk factors integrated through a GIS

    International Nuclear Information System (INIS)

    Toth, D.M.; O'Connell, W.J.

    1996-01-01

    The assessment of potential alternative routes for the shipment of spent nuclear fuel was simplified through the use of comparative risk factors evaluated using detailed route and environmental attributes. The route characteristics, integrated into risk measures, vary strongly with location and were developed from national, state, and local sources. The route data and evaluation were managed using a geographic information system (GIS). An assessment of four real North Florida routes was performed and an interstate highway route exhibited the lowest risk based on the application of the risk factors

  5. A comparative analysis for multiattribute selection among renewable energy alternatives using fuzzy axiomatic design and fuzzy analytic hierarchy process

    Energy Technology Data Exchange (ETDEWEB)

    Kahraman, Cengiz; Kaya, Ihsan; Cebi, Selcuk [Istanbul Technical University, Department of Industrial Engineering, 34367, Macka-Istanbul (Turkey)

    2009-10-15

    Renewable energy is the energy generated from natural resources such as sunlight, wind, rain, tides and geothermal heat which are renewable. Energy resources are very important in perspective of economics and politics for all countries. Hence, the selection of the best alternative for any country takes an important role for energy investments. Among decision-making methodologies, axiomatic design (AD) and analytic hierarchy process (AHP) are often used in the literature. The fuzzy set theory is a powerful tool to treat the uncertainty in case of incomplete or vague information. In this paper, fuzzy multicriteria decision- making methodologies are suggested for the selection among renewable energy alternatives. The first methodology is based on the AHP which allows the evaluation scores from experts to be linguistic expressions, crisp, or fuzzy numbers, while the second is based on AD principles under fuzziness which evaluates the alternatives under objective or subjective criteria with respect to the functional requirements obtained from experts. The originality of the paper comes from the fuzzy AD application to the selection of the best renewable energy alternative and the comparison with fuzzy AHP. In the application of the proposed methodologies the most appropriate renewable energy alternative is determined for Turkey. (author)

  6. Design and control of an alternative distillation sequence for bioethanol purification

    DEFF Research Database (Denmark)

    Errico, Massimiliano; Ramírez-Márquez, César; Torres Ortega, Carlo Edgar

    2015-01-01

    BACKGROUND: Bioethanol is a green fuel considered to be a sustainable alternative to petro-derived gasoline. The transport sector contributes significantly to carbon dioxide emission and consequently has a negative impact on the air quality and is responsible for the increase of the greenhouse...

  7. Including alternative resources in state renewable portfolio standards: Current design and implementation experience

    International Nuclear Information System (INIS)

    Heeter, Jenny; Bird, Lori

    2013-01-01

    As of October 2012, 29 states, the District of Columbia, and Puerto Rico have instituted a renewable portfolio standard (RPS). Each state policy is unique, varying in percentage targets, timetables, and eligible resources. Increasingly, new RPS polices have included alternative resources. Alternative resources have included energy efficiency, thermal resources, and, to a lesser extent, non-renewables. This paper examines state experience with implementing renewable portfolio standards that include energy efficiency, thermal resources, and non-renewable energy and explores compliance experience, costs, and how states evaluate, measure, and verify energy efficiency and convert thermal energy. It aims to gain insights from the experience of states for possible federal clean energy policy as well as to share experience and lessons for state RPS implementation. - Highlights: • Increasingly, new RPS policies have included alternative resources. • Nearly all states provide a separate tier or cap on the quantity of eligible alternative resources. • Where allowed, non-renewables and energy efficiency are being heavily utilized

  8. The ChemScreen project to design a pragmatic alternative approachto predict reproductive toxicity of chemicals

    NARCIS (Netherlands)

    Van der Burg, B.; Wedebye, E.B.; Dietrich, D.R.; Jaworska, J.; Mangelsdorf, I.; Paune, E.; Schwarz, M.; Piersma, A.H.; Kroese, E.D.

    2015-01-01

    There is a great need for rapid testing strategies for reproductive toxicity testing, avoiding animal use.The EU Framework program 7 project ChemScreen aimed to fill this gap in a pragmatic manner prefer-ably using validated existing tools and place them in an innovative alternative testing

  9. Alternative Fuels and Hybrid Technology: A Classroom Activity Designed to Evaluate a Contemporary Problem

    Science.gov (United States)

    Roy MacArthur, Amy H.; Copper, Christine L.

    2009-01-01

    As petroleum reserves are being depleted worldwide and energy costs are increasing, the use of alternative fuels is being more widely considered as a solution to the impending energy crisis. In this classroom activity students are presented with a real-world problem in which they must evaluate the properties and environmental impacts of a variety…

  10. Alternative Fistula Risk Score for Pancreatoduodenectomy (a-FRS): Design and International External Validation

    NARCIS (Netherlands)

    Mungroop, Timothy H.; van Rijssen, L. Bengt; van Klaveren, David; Smits, F. Jasmijn; van Woerden, Victor; Linnemann, Ralph J.; de Pastena, Matteo; Klompmaker, Sjors; Marchegiani, Giovanni; Ecker, Brett L.; van Dieren, Susan; Bonsing, Bert; Busch, Olivier R.; van Dam, Ronald M.; Erdmann, Joris; van Eijck, Casper H.; Gerhards, Michael F.; van Goor, Harry; van der Harst, Erwin; de Hingh, Ignace H.; de Jong, Koert P.; Kazemier, Geert; Luyer, Misha; Shamali, Awad; Barbaro, Salvatore; Armstrong, Thomas; Takhar, Arjun; Hamady, Zaed; Klaase, Joost; Lips, Daan J.; Molenaar, I. Quintus; Nieuwenhuijs, Vincent B.; Rupert, Coen; van Santvoort, Hjalmar C.; Scheepers, Joris J.; van der Schelling, George P.; Bassi, Claudio; Vollmer, Charles M.; Steyerberg, Ewout W.; Abu Hilal, Mohammed; Groot Koerkamp, Bas; Besselink, Marc G.

    2017-01-01

    The aim of this study was to develop an alternative fistula risk score (a-FRS) for postoperative pancreatic fistula (POPF) after pancreatoduodenectomy, without blood loss as a predictor. Blood loss, one of the predictors of the original-FRS, was not a significant factor during 2 recent external

  11. Routing in opportunistic networks

    CERN Document Server

    Dhurandher, Sanjay; Anpalagan, Alagan; Vasilakos, Athanasios

    2013-01-01

    This book provides a comprehensive guide to selected topics, both ongoing and emerging, in routing in OppNets. The book is edited by worldwide technical leaders, prolific researchers and outstanding academics, Dr. Isaac Woungang and co-editors, Dr. Sanjay Kumar Dhurandher, Prof. Alagan Anpalagan and Prof. Athanasios Vasilakos. Consisting of contributions from well known and high profile researchers and scientists in their respective specialties, the main topics that are covered in this book include mobility and routing, social-aware routing, context-based routing, energy-aware routing, incentive-aware routing, stochastic routing, modeling of intermittent connectivity, in both infrastructure and infrastructure-less OppNets. Key Features: Discusses existing and emerging techniques for routing in infrastructure and infrastructure-less OppNets. Provides a unified covering of otherwise disperse selected topics on routing in infrastructure and infrastructure-less OppNets.  Includes a set of PowerPoint slides and g...

  12. Generating Alternative Engineering Designs by Integrating Desktop VR with Genetic Algorithms

    Science.gov (United States)

    Chandramouli, Magesh; Bertoline, Gary; Connolly, Patrick

    2009-01-01

    This study proposes an innovative solution to the problem of multiobjective engineering design optimization by integrating desktop VR with genetic computing. Although, this study considers the case of construction design as an example to illustrate the framework, this method can very much be extended to other engineering design problems as well.…

  13. Hazmat Routes (National)

    Data.gov (United States)

    Department of Transportation — The Federal Motor Carrier Safety Administration (FMCSA) Hazardous Material Routes (NTAD) were developed using the 2004 First Edition TIGER/Line files. The routes are...

  14. Selection and development of innovative design alternatives : Ethical, social and uncertainty issues

    NARCIS (Netherlands)

    Jacobs, J.F.

    2015-01-01

    Innovative engineering design shapes the development of novel technologies and is ethically as well as socially relevant, because it affects what kind of possibilities and consequences will arise. A major challenge in engineering design work on innovative technologies is the multitude of

  15. Investigation of Alternative Return Strategies for Orion Trans-earth Injection Design Options

    Science.gov (United States)

    Marchand, Belinda G.; Scarritt, Sara K.; Howell, Kathleen C.; Weeks, Michael W.

    2010-01-01

    The purpose of this study is to investigate alternative return strategies for the Orion trans-Earth injection (TEI) phase. A dynamical systems analysis approach considers the structure of the stable and unstable Sun perturbed Earth-Moon manifolds near the Earth-Moon interface region. A hybrid approach, then, combines the results from this analysis with classical two-body methods in a targeting process that seeks to expand the window of return opportunities in a precision entry scenario. The resulting startup arcs can be used, for instance, to enhance the block set of solutions available onboard during an autonomous targeting process.

  16. DESIGNING CULTURALLY CONSCIOUS ALTERNATIVE DISPUTE RESOLUTION TO FOSTER ASIAN ECONOMIC DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Mrs. Herliana

    2011-06-01

    Full Text Available Creating an Asian model of alternative dispute resolution which considers Asian cultures is important. A mere adoption of western standard will less likely accommodate Asian’s unique way of handling disputes. Culture-related problems can be avoided if international commercial mediation or arbitration is tuned in to cultural needs and expectations. Penyusunan model alternatif penyelesaian sengketa gaya Asia yang mengakomodasi budaya setempat penting untuk dilakukan. Penerapan standar barat tidak selamanya cocok dengan cara unik orang Asia dalam memandang suatu sengketa. Konflik kultural dapat dihindari apabila mediasi atau arbitrase bisnis internasional disesuaikan dengan kebutuhan budaya setempat.

  17. Thermal/mechanical simulation and laboratory fatigue testing of an alternative yttria tetragonal zirconia polycrystal core-veneer all-ceramic layered crown design.

    Science.gov (United States)

    Bonfante, Estevam A; Rafferty, Brian; Zavanelli, Ricardo A; Silva, Nelson R F A; Rekow, Elizabeth D; Thompson, Van P; Coelho, Paulo G

    2010-04-01

    This study evaluated the stress levels at the core layer and the veneer layer of zirconia crowns (comprising an alternative core design vs. a standard core design) under mechanical/thermal simulation, and subjected simulated models to laboratory mouth-motion fatigue. The dimensions of a mandibular first molar were imported into computer-aided design (CAD) software and a tooth preparation was modeled. A crown was designed using the space between the original tooth and the prepared tooth. The alternative core presented an additional lingual shoulder that lowered the veneer bulk of the cusps. Finite element analyses evaluated the residual maximum principal stresses fields at the core and veneer of both designs under loading and when cooled from 900 degrees C to 25 degrees C. Crowns were fabricated and mouth-motion fatigued, generating master Weibull curves and reliability data. Thermal modeling showed low residual stress fields throughout the bulk of the cusps for both groups. Mechanical simulation depicted a shift in stress levels to the core of the alternative design compared with the standard design. Significantly higher reliability was found for the alternative core. Regardless of the alternative configuration, thermal and mechanical computer simulations showed stress in the alternative core design comparable and higher to that of the standard configuration, respectively. Such a mechanical scenario probably led to the higher reliability of the alternative design under fatigue.

  18. Water balance relationships in four alternative cover designs for radioactive and mixed waste landfills

    International Nuclear Information System (INIS)

    Warren, R.W.; Hakonson, T.E.; Trujillo, G.

    1994-01-01

    Preliminary results are presented from a field study to evaluate the relative hydrologic performance of various landfill capping technologies installed by the Los Alamos National Laboratory at Hill Air Force Base, Utah. Four cover designs (two Los Alamos capillary barrier designs, one modified EPA RCRA design, and one conventional design) were installed in large lysimeters instrumented to monitor the fate of natural precipitation between 01 January 1990 and 20 September 1993. After 45 months of study, results showed that the cover designs containing barrier layers were effective in reducing deep percolation as compared to a simple soil cap design. The RCRA cover, incorporating a clay hydraulic barrier, was the most effective of all cover designs in controlling percolation but was not 100% effective. Over 90% of all percolation and barrier lateral flow occurred during the months of February through May of each year, primarily as a result of snow melt, early spring rains and low evapotranspiration. Gravel mulch surface treatments (70--80% coverage) were effective in reducing runoff and erosion. The two plots receiving gravel mulch treatments exhibited equal but enhanced amounts of evapotranspiration despite the fact that one plot was planted with additional shrubs

  19. GREENER CHEMICAL PROCESS DESIGN ALTERNATIVES ARE REVEALED USING THE WASTE REDUCTION DECISION SUPPORT SYSTEM (WAR DSS)

    Science.gov (United States)

    The Waste Reduction Decision Support System (WAR DSS) is a Java-based software product providing comprehensive modeling of potential adverse environmental impacts (PEI) predicted to result from newly designed or redesigned chemical manufacturing processes. The purpose of this so...

  20. Evaluation of occupational health interventions using a randomized controlled trial: challenges and alternative research designs

    NARCIS (Netherlands)

    Schelvis, R.M; Oude Hengel, K.M.; Burdorf, A.; Blatter, B.M.; Strijk, J.E.; Beek, A.J. van

    2015-01-01

    Occupational health researchers regularly conduct evaluative intervention research for which a randomized controlled trial (RCT) may not be the most appropriate design (eg, effects of policy measures, organizational interventions on work schedules). This article demonstrates the appropriateness of

  1. StateGEN/StateNET - A structured method to perform route comparisons

    International Nuclear Information System (INIS)

    Cashwell, J.W.; Erickson, C.M.

    1989-01-01

    StateGEN/StateNET is a modeling structure and routing algorithm designed expressly to address the needs of state and local governments to perform analyses of routing alternatives. StateGEN/StateNET is designed to permit the user to construct a network and assign attributes of interest to the network on a personal computer (PC). The completed network is then transferred via a modem to the TRANSNET system and the preferred route is determined based upon attribute weights assigned by the user. This modeling structure permits the state or local government to perform a routing analysis, such as that required by the US Department of Transportation (DOT) for Highway Route-Controlled Quantity shipments of radioactive materials, with a minimum of resources. StateGEN/StateNET provides a computerized version of the DOT guidelines or allows the user to structure their own network parameters. Sandia National Laboratories (SNL) is the Department of Energy (DOE) lead organization for transportation research and development. The DOE Office of Defense Programs has been the prime sponsor of development of models and associated databases used to analyze the impacts of the transportation of radioactive materials. The routing algorithms used in StateGEN/StateNET were based on the existing models on TRANSNET, a system which was developed to enable outside users to access analytical codes and associated data developed for the DOE

  2. Impact of Rate Design Alternatives on Residential Solar Customer Bills. Increased Fixed Charges, Minimum Bills and Demand-based Rates

    Energy Technology Data Exchange (ETDEWEB)

    Bird, Lori [National Renewable Energy Lab. (NREL), Golden, CO (United States); Davidson, Carolyn [National Renewable Energy Lab. (NREL), Golden, CO (United States); McLaren, Joyce [National Renewable Energy Lab. (NREL), Golden, CO (United States); Miller, John [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-09-01

    With rapid growth in energy efficiency and distributed generation, electric utilities are anticipating stagnant or decreasing electricity sales, particularly in the residential sector. Utilities are increasingly considering alternative rates structures that are designed to recover fixed costs from residential solar photovoltaic (PV) customers with low net electricity consumption. Proposed structures have included fixed charge increases, minimum bills, and increasingly, demand rates - for net metered customers and all customers. This study examines the electricity bill implications of various residential rate alternatives for multiple locations within the United States. For the locations analyzed, the results suggest that residential PV customers offset, on average, between 60% and 99% of their annual load. However, roughly 65% of a typical customer's electricity demand is non-coincidental with PV generation, so the typical PV customer is generally highly reliant on the grid for pooling services.

  3. Sıkışma: An Alternative Information Design Project for Ihlamur Pavilions Istanbul.

    Science.gov (United States)

    Özmen, Melike

    2016-01-01

    Sıkışma is a transmedia information design project, which focuses on Ihlamur Pavilions and Ihlamur area. Ihlamur hosts Ihlamur Pavilions since 19th Century. It is located within Beşiktaş district in Istanbul. Nowadays the buildings belong to TBMM (The Grand National Assembly of Turkey) National Palaces and used as a Museum- Café. There is a conventional wayfinding & signage system for outdoor areas of the Pavilions. The system also includes two separate boards focusing on the history of Ihlamur and Ihlamur Pavilions. However, the information provided on these boards seems inadequate and the boards are physically damaged. According Universal Design approach it is possible to achieve good and functional design and solve the inadequacy problem by physically fixing information boards and re-setting the environment around the information boards according to Universal Design principles. Although, these principles provide solutions for important issues such as mobility, stability and accessibility, it doesn't provide sufficient proof of user engagement in terms of the creation of the content. The project Sıkışma offers an approach, which is concerned with content as with form and suggests that it is possible to infer a universal form from the content created through personal experience of the designer as a user. It is also intended to represent the past and the present through the project and to create an understanding of plausible scenarios of the unknown future in the viewers' mind.

  4. Harnessing Alternative Energy Sources to Enhance the Design of a Wave Generator

    Science.gov (United States)

    Bravo, A.

    2017-12-01

    Wave energy has the power to replace a non-renewable source of electricity for a home near the ocean. I built a small-scale wave generator capable of producing approximately 5 volts of electricity. The generator is an array of 16 small generators, each consisting of 200 feet of copper wire, 12 magnets, and a buoy. I tested my design in the Pacific Ocean and was able to power a string of lights I had attached to the generator. While the waves in the ocean moved my buoys, my design was powered by the vertical motion of the waves. My generator was hit with significant horizontal wave motion, and I realized I wasn't taking advantage of that direction of motion. To make my generator produce more electricity, I experimented with capturing the energy of the horizontal motion of water and incorporated that into my generator design. My generator, installed in the ocean, is also exposed to sun and wind, and I am exploring the potential of solar and wind energy collection in my design to increase the electricity output. Once I have maximized my electricity output, I would like to explore scaling up my design.

  5. A framework to support decision making in the selection of sustainable drainage system design alternatives.

    Science.gov (United States)

    Wang, Mingming; Sweetapple, Chris; Fu, Guangtao; Farmani, Raziyeh; Butler, David

    2017-10-01

    This paper presents a new framework for decision making in sustainable drainage system (SuDS) scheme design. It integrates resilience, hydraulic performance, pollution control, rainwater usage, energy analysis, greenhouse gas (GHG) emissions and costs, and has 12 indicators. The multi-criteria analysis methods of entropy weight and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) were selected to support SuDS scheme selection. The effectiveness of the framework is demonstrated with a SuDS case in China. Indicators used include flood volume, flood duration, a hydraulic performance indicator, cost and resilience. Resilience is an important design consideration, and it supports scheme selection in the case study. The proposed framework will help a decision maker to choose an appropriate design scheme for implementation without subjectivity. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Alternative concepts for Low-Level Radioactive Waste Disposal: Conceptual design report

    International Nuclear Information System (INIS)

    1987-06-01

    This conceptual design report is provided by the Department of Energy's Nuclear Energy Low-Level Waste Management Program to assist states and compact regions in developing new low-level radioactive waste (LLW) disposal facilities in accordance with the Low-Level Radioactive Waste Policy Amendment Act of 1985. The report provides conceptual designs and evaluations of six widely considered concepts for LLW disposal. These are shallow land disposal (SLD), intermediate depth disposal (IDD), below-ground vaults (BGV), above-ground vaults (AGV), modular concrete canister disposal (MCCD), earth-mounded concrete bunker (EMCB). 40 refs., 45 figs., 77 tabs

  7. Randomized Controlled Studies and Alternative Designs in Outcome Studies: Challenges and Opportunities

    Science.gov (United States)

    Shadish, William R.

    2011-01-01

    This article reviews several decades of the author's meta-analytic and experimental research on the conditions under which nonrandomized experiments can approximate the results from randomized experiments (REs). Several studies make clear that we can expect accurate effect estimates from the regression discontinuity design, though its statistical…

  8. Vehicle perceptibilty : reflectorized registration plates and alternative means : function, design and application.

    NARCIS (Netherlands)

    Griep, D.J. Thoenes, E. Schreuder, D.A. & Kranenburg, A.

    1970-01-01

    In November 1967 the Minister of Transport and Waterways in the Netherlands asked the Institute for Road Safety Research SWOV to examine the advisable design of reflectorized registration plates from the aspect of perceptibility. Allowance had to be made for the identification of motor vehicles.

  9. Service design as the ground for alternative social and economic scenarios

    DEFF Research Database (Denmark)

    Sbordone, Maria Antonietta; Morelli, Nicola

    2017-01-01

    , such as experience, time, knowledge, new roles in working and consuming. The actions triggered by service design move the center of value production from material goods to immaterial actions and performances. Services also propose new dynamics of relational mediation among stakeholders in social and economic systems...

  10. Alternative designs for megavoltage machines for cancer treatment in developing countries

    International Nuclear Information System (INIS)

    Borras, C.; Svensson, H.; Hanson, G.P.

    1996-01-01

    In developing countries radiation therapy is often performed with antiquated cobalt-60 units, the radioactive sources of which are long decayed and, thus, treatments are ineffective. Furthermore the cost involved in the disposal of spent radionuclide sources discourages owners from proper removal and storage, and accidents occur. Although present design of microwave electron linear accelerators provide excellent beam characteristics, developing countries in many locations do not have the infrastructure to maintain such machines. After an analysis of the radiotherapy situation world-wide - especially from the viewpoint of maintenance - a consensus was reached on the radiotherapy equipment performance requirements. To meet these requirements, several accelerator designs were considered. Among the most promising new designs were the klystron/linac and the high frequency linear accelerator, the microtron in a radiation head, the high frequency betatron, also in a radiation accelerator, and DC accelerators. Possible treatment designs, including those of modular nature, were presented. Since it is estimated that by the year 2015, barring a dramatic and unforeseen cure for cancer, a total of 10,000 machines will be needed to provide treatment for an estimated 10 million new cases per year in developing countries, the impact of such high technology simple machine could be substantial in providing equity and quality for the management of cancer patients. 4 refs, 2 tabs

  11. Non-Parametric Inference for Ordered Alternatives in a Randomized Block Design

    Science.gov (United States)

    Hettmansperger, Thomas P.

    1975-01-01

    Treats the problem of testing an ordered hypothesis based on the ranks of the data. Statistical procedures for the randomized block design with more than one observation per cell are derived. Multiple comparisions and estimation procedures are included. (Author/RC)

  12. Adopting the alternate reality game approach in the design of the Singa environment

    CSIR Research Space (South Africa)

    Dlodlo, N

    2010-01-01

    Full Text Available Playing games, especially electronic games, is a popular free-time activity among children and adolescents and these games seem to have a prominent role in the culture of young people. It is with this in mind that the SINGA environment was designed...

  13. An alternative approach to compensators design for photon beams used in radiotherapy

    International Nuclear Information System (INIS)

    Jurkovic, S.; Zauhar, G.; Bistrovic, M.; Faj, D.; Kaliman, Z.; Smilovic Radojcic, D.

    2007-01-01

    The use of compensators in order to achieve desired dose distribution has a long history and is a well-established technique in radiation therapy planning. There are several different calculation methods for determining a compensator's thickness. An alternative method that is based on the Cunningham's modification of Clarkson's method to calculate scattered radiation in beams with an inhomogeneous cross-section is proposed. It is well known that the total dose distribution of radiotherapy photon beam consists of the contributions of the primary beam, attenuated by the tissue layer, and the scattered radiation generated by the primary radiation in single and multiple photon scatter events. The scattered component can be represented as a function of the primary radiation. The central point of our method is the numerical estimation of the primary distribution required to achieve the desired total distribution. Now using the calculated primary distribution, the shape of the modulator could be determined. In this way the contribution of the scattered component is validated in a more accurate way than using effective attenuation coefficients, which is a common practice. The method is verified in various clinical situations and compared with the standard method. The accuracy, although dependent on geometry, was improved by at least 2%. With more complex geometries there is an even higher gain in accuracy with our method when compared to the standard method

  14. Evaluation of design alternatives for sewing scissors with respect to hand performance, discomfort and usability.

    Science.gov (United States)

    Dianat, Iman; Asadollahi, Soudabeh; Nedaei, Moein

    2017-09-22

    The effects of three re-designed models of sewing scissors on hand performance measures, discomfort and usability were investigated, and the results were compared with those of conventional scissors. Adjustments were made to the scissors handle with emphasis on more neutral wrist postures (bent handle - model A), correction of the thumb's position and movements (model B) and reducing hand/finger discomfort (model C) while working with the tool. The results showed some improvements in hand performance, muscular effort, usability and discomfort with model B compared to the conventional model. Better hand performance and usability and lower discomfort were recorded with model C compared to the conventional model. The results suggest that the correction of the thumb's position and movement (model B) or even reduced hand/finger discomfort (model C) are perhaps more important considerations in scissors design than improved wrist posture (model A) for improving users' performance and usability of the tool.

  15. Ventilation of high-speed flows, an alternating methodology for the ventilator design

    International Nuclear Information System (INIS)

    Saldarriaga V, Juan G.; Navarrete, J.; Galeano B, Luis A.

    1996-01-01

    This article is about a research developed at Universidad de los Andes on the ventilation of high velocity flows as prevention against cavitations erosion. The research was a consequence of the results found in the physical model of the Guavio River Hydroelectric Project near Bogota and was based in a general model study of a spillway with ventilation system, which did not represent a particular prototype. In the Guavio study one conclusion was obtained:in every ventilation system there are three unknowns which are the air discharge injected to the water flow (design object variable), the sub pressure under the water jet and the jump length of that jet. In the research those three variables were studied using dimensional analysis and multivariable regressions in order to find a set of three equations that allow the design of this type of structures. The new equations are more general than those reported in technical literature

  16. Exploring Alternatives for Representing and Accessing Design Knowledge About Enterprise Integration

    Science.gov (United States)

    Umapathy, Karthikeyan; Purao, Sandeep

    Enterprise integration refers to solutions that facilitate meaningful interactions among heterogeneous legacy applications. The scale, complexity and specificity of most enterprise integration efforts mean that design knowledge for enterprise integration has resisted codification. Important exceptions to this include: use of Business Process Models (BPM) to understand integration requirements; and Enterprise Integration Patterns (EIP), which present designers with abstract descriptions of recurring design tactics for integrating applications. The two, however, can be at odds. BPM encourages the control flow perspective; whereas EIP codifies an operational perspective. Mapping between the two to develop coherent solutions, therefore, tends to be problematic. To bridge the gap, we suggest an approach that builds on the theory of speech acts. We develop essential components of such an approach, including a re-representation of EIP as structures of speech acts, a characterization of tasks in BPM with action types, and a mapping between speech acts and action types. These components are accompanied by inference rules that produce a mapping between sets of tasks in a business process and structures of speech acts to allow reasoning on identification of appropriate EIPs for given set of tasks. We demonstrate usefulness of the proposed approach by application to industry cases.

  17. Telemonitoring after discharge from hospital with heart failure: cost-effectiveness modelling of alternative service designs.

    Science.gov (United States)

    Thokala, Praveen; Baalbaki, Hassan; Brennan, Alan; Pandor, Abdullah; Stevens, John W; Gomersall, Tim; Wang, Jenny; Bakhai, Ameet; Al-Mohammad, Abdallah; Cleland, John; Cowie, Martin R; Wong, Ruth

    2013-09-18

    To estimate the cost-effectiveness of remote monitoring strategies versus usual care for adults recently discharged after a heart failure (HF) exacerbation. Decision analysis modelling of cost-effectiveness using secondary data sources. Acute hospitals in the UK. Patients recently discharged (within 28 days) after a HF exacerbation. Structured telephone support (STS) via human to machine (STS HM) interface, (2) STS via human to human (STS HH) contact and (3) home telemonitoring (TM), compared with (4) usual care. The incremental cost per quality-adjusted life year (QALY) gained by each strategy compared to the next most effective alternative and the probability of each strategy being cost-effective at varying willingness to pay per QALY gained. TM was the most cost-effective strategy in the scenario using these base case costs. Compared with usual care, TM had an estimated incremental cost effectiveness ratio (ICER) of £11 873/QALY, whereas STS HH had an ICER of £228 035/QALY against TM. STS HM was dominated by usual care. Threshold analysis suggested that the monthly cost of TM has to be higher than £390 to have an ICER greater than £20 000/QALY against STS HH. Scenario analyses performed using higher costs of usual care, higher costs of STS HH and lower costs of TM do not substantially change the conclusions. Cost-effectiveness analyses suggest that TM was an optimal strategy in most scenarios, but there is considerable uncertainty in relation to clear descriptions of the interventions and robust estimation of costs.

  18. Testing alternative designs for a roadside animal detection system using a driving simulator

    Directory of Open Access Journals (Sweden)

    Molly K. Grace

    2015-07-01

    Full Text Available Objectives: A Roadside Animal Detection System (RADS was installed in January 2012 along Highway 41 through Big Cypress National Preserve in Florida, USA in an attempt to reduce wildlife-vehicle collisions. The system uses flashing warning signs to alert drivers when a large animal is near the road. However, we suspected that the RADS warning signs could be ignored by drivers because they resemble other conventional signs. We hypothesized that word-based warning signs (current design are less effective than picture-based signs at catching drivers’ attention. Methods: We used a driving simulator to test (1 the effects of the RADS on collision rate, driver speed, and latency to brake; and (2 whether the RADS would be more effective if warning signs were picture-based. Participants were randomly assigned to one of three treatments: no warning (control, word-based RADS signs (current design, and picture-based RADS signs (proposed design. During the simulations, a deer entered the road in front of the driver, and we recorded whether drivers “crashed” or not. Results: Both the picture-based and word-based RADS signs resulted in significantly lower crash probabilities. The picture-based RADS signs performed better than the word-based signs in reducing speed and latency to brake, although the effect varied between twilight and night. However, the word-based RADS signs still did produce significant reductions in speed and braking latency. Conclusions: We conclude that the word-based RADS in Big Cypress should help prevent dangerous wildlife-vehicle collisions, but that redesigning the warning signs to be picture-based could yield even greater benefits.

  19. Interplanetary Trajectory Design for the Asteroid Robotic Redirect Mission Alternate Approach Trade Study

    Science.gov (United States)

    Merrill, Raymond Gabriel; Qu, Min; Vavrina, Matthew A.; Englander, Jacob A.; Jones, Christopher A.

    2014-01-01

    This paper presents mission performance analysis methods and results for the Asteroid Robotic Redirect Mission (ARRM) option to capture a free standing boulder on the surface of a 100 m or larger NEA. It details the optimization and design of heliocentric low-thrust trajectories to asteroid targets for the ARRM solar electric propulsion spacecraft. Extensive searches were conducted to determine asteroid targets with large pick-up mass potential and potential observation opportunities. Interplanetary trajectory approximations were developed in method based tools for Itokawa, Bennu, 1999 JU3, and 2008 EV5 and were validated by end-to-end integrated trajectories.

  20. COMPARING PUMA ROBOT ARM WITH THE HUMAN ARM MOVEMENTS; AN ALTERNATIVE ROBOTIC ARM SHOULDER DESIGN

    Directory of Open Access Journals (Sweden)

    Mustafa BOZDEMİR

    1999-02-01

    Full Text Available Using the robotic arms instead of human power becomes increasingly widespread nowadays. Widening of the robotic arms usage field is parallel to improvement of movement capability of it. In this study PUMA Robotic Arm System that is a developed system of the robotic arms was compared with a human arm due to movement. A new joint was added to PUMA Robotic Arm System to have the movements similar to the human shoulder joint. Thus, a shoulder was designed that can make movements through the sides in addition to fore and back movement.

  1. COMPARING PUMA ROBOT ARM WITH THE HUMAN ARM MOVEMENTS; AN ALTERNATIVE ROBOTIC ARM SHOULDER DESIGN

    OpenAIRE

    BOZDEMİR, Mustafa; ADIGÜZEL, Esat

    1999-01-01

    Using the robotic arms instead of human power becomes increasingly widespread nowadays. Widening of the robotic arms usage field is parallel to improvement of movement capability of it. In this study PUMA Robotic Arm System that is a developed system of the robotic arms was compared with a human arm due to movement. A new joint was added to PUMA Robotic Arm System to have the movements similar to the human shoulder joint. Thus, a shoulder was designed that can make movements through the sides...

  2. Alternative design of pipe sleeve for liquid removal mechanism in mortar slab layer

    Science.gov (United States)

    Nazri, W. M. H. Wan; Anting, N.; Lim, A. J. M. S.; Prasetijo, J.; Shahidan, S.; Din, M. F. Md; Anuar, M. A. Mohd

    2017-11-01

    Porosity is one of the mortar’s characteristics that can cause problems, especially in the room space that used high amount of water, such as bathrooms. Waterproofing is one of the technology that normally used to minimize this problem which is preventing deep penetration of liquid water or moisture into underlying concrete layers. However, without the proper mechanism to remove liquid water and moisture from mortar system, waterproofing layer tends to be damaged after a long period of time by the static formation of liquid water and moisture at mortar layer. Thus, a solution has been proposed to drain out water that penetrated into the mortar layer. This paper introduces a new solution using a Modified Pipe Sleeve (MPS) that installed at the mortar layer. The MPS has been designed considering the percentage surface area of the pipe sleeve that having contact with mortar layer (2%, 4%, 6%, 8% and 10%) with angle of holes of 60°. Infiltration test and flow rate test have been conducted to identify the effectiveness of the MPS in order to drain out liquid water or moisture from the mortar layer. In this study shows that, MPS surface area 10%, angled 60°, function effectively as a water removal compared to other design.

  3. A MINE alternative to D-optimal designs for the linear model.

    Directory of Open Access Journals (Sweden)

    Amanda M Bouffier

    Full Text Available Doing large-scale genomics experiments can be expensive, and so experimenters want to get the most information out of each experiment. To this end the Maximally Informative Next Experiment (MINE criterion for experimental design was developed. Here we explore this idea in a simplified context, the linear model. Four variations of the MINE method for the linear model were created: MINE-like, MINE, MINE with random orthonormal basis, and MINE with random rotation. Each method varies in how it maximizes the MINE criterion. Theorem 1 establishes sufficient conditions for the maximization of the MINE criterion under the linear model. Theorem 2 establishes when the MINE criterion is equivalent to the classic design criterion of D-optimality. By simulation under the linear model, we establish that the MINE with random orthonormal basis and MINE with random rotation are faster to discover the true linear relation with p regression coefficients and n observations when p>>n. We also establish in simulations with n<100, p=1000, σ=0.01 and 1000 replicates that these two variations of MINE also display a lower false positive rate than the MINE-like method and additionally, for a majority of the experiments, for the MINE method.

  4. On Designing Thermal-Aware Localized QoS Routing Protocol for in-vivo Sensor Nodes in Wireless Body Area Networks

    Directory of Open Access Journals (Sweden)

    Muhammad Mostafa Monowar

    2015-06-01

    Full Text Available In this paper, we address the thermal rise and Quality-of-Service (QoS provisioning issue for an intra-body Wireless Body Area Network (WBAN having in-vivo sensor nodes. We propose a thermal-aware QoS routing protocol, called TLQoS, that facilitates the system in achieving desired QoS in terms of delay and reliability for diverse traffic types, as well as avoids the formation of highly heated nodes known as hotspot(s, and keeps the temperature rise along the network to an acceptable level. TLQoS exploits modular architecture wherein different modules perform integrated operations in providing multiple QoS service with lower temperature rise. To address the challenges of highly dynamic wireless environment inside the human body. TLQoS implements potential-based localized routing that requires only local neighborhood information. TLQoS avoids routing loop formation as well as reduces the number of hop traversal exploiting hybrid potential, and tuning a configurable parameter. We perform extensive simulations of TLQoS, and the results show that TLQoS has significant performance improvements over state-of-the-art approaches.

  5. On Designing Thermal-Aware Localized QoS Routing Protocol for in-vivo Sensor Nodes in Wireless Body Area Networks.

    Science.gov (United States)

    Monowar, Muhammad Mostafa; Bajaber, Fuad

    2015-06-15

    In this paper, we address the thermal rise and Quality-of-Service (QoS) provisioning issue for an intra-body Wireless Body Area Network (WBAN) having in-vivo sensor nodes. We propose a thermal-aware QoS routing protocol, called TLQoS, that facilitates the system in achieving desired QoS in terms of delay and reliability for diverse traffic types, as well as avoids the formation of highly heated nodes known as hotspot(s), and keeps the temperature rise along the network to an acceptable level. TLQoS exploits modular architecture wherein different modules perform integrated operations in providing multiple QoS service with lower temperature rise. To address the challenges of highly dynamic wireless environment inside the human body. TLQoS implements potential-based localized routing that requires only local neighborhood information. TLQoS avoids routing loop formation as well as reduces the number of hop traversal exploiting hybrid potential, and tuning a configurable parameter. We perform extensive simulations of TLQoS, and the results show that TLQoS has significant performance improvements over state-of-the-art approaches.

  6. A review of techniques to determine alternative selection in design for remanufacturing

    Science.gov (United States)

    Noor, A. Z. Mohamed; Fauadi, M. H. F. Md; Jafar, F. A.; Mohamad, N. R.; Yunos, A. S. Mohd

    2017-10-01

    This paper discusses the techniques used for optimization in manufacturing system. Although problem domain is focused on sustainable manufacturing, techniques used to optimize general manufacturing system were also discussed. Important aspects of Design for Remanufacturing (DFReM) considered include indexes, weighted average, grey decision making and Fuzzy TOPSIS. The limitation of existing techniques are most of them is highly based on decision maker’s perspective. Different experts may have different understanding and eventually scale it differently. Therefore, the objective of this paper is to determine available techniques and identify the lacking feature in it. Once all the techniques have been reviewed, a decision will be made by create another technique which should counter the lacking of discussed techniques. In this paper, shows that the hybrid computation of Fuzzy Analytic Hierarchy Process (AHP) and Artificial Neural Network (ANN) is suitable and fill the gap of all discussed technique.

  7. Route Availabililty Planning Tool -

    Data.gov (United States)

    Department of Transportation — The Route Availability Planning Tool (RAPT) is a weather-assimilated decision support tool (DST) that supports the development and execution of departure management...

  8. Life cycle assessment of a power tower concentrating solar plant and the impacts of key design alternatives.

    Science.gov (United States)

    Whitaker, Michael B; Heath, Garvin A; Burkhardt, John J; Turchi, Craig S

    2013-06-04

    A hybrid life cycle assessment (LCA) is used to evaluate four sustainability metrics over the life cycle of a power tower concentrating solar power (CSP) facility: greenhouse gas (GHG) emissions, water consumption, cumulative energy demand (CED), and energy payback time (EPBT). The reference design is for a dry-cooled, 106 MW(net) power tower facility located near Tucson, AZ that uses a mixture of mined nitrate salts as the heat transfer fluid and storage medium, a two-tank thermal energy storage system designed for six hours of full load-equivalent storage, and receives auxiliary power from the local electric grid. A thermocline-based storage system, synthetically derived salts, and natural gas auxiliary power are evaluated as design alternatives. Over its life cycle, the reference plant is estimated to have GHG emissions of 37 g CO2eq/kWh, consume 1.4 L/kWh of water and 0.49 MJ/kWh of energy, and have an EPBT of 15 months. Using synthetic salts is estimated to increase GHG emissions by 12%, CED by 7%, and water consumption by 4% compared to mined salts. Natural gas auxiliary power results in greater than 10% decreases in GHG emissions, water consumption, and CED. The thermocline design is most advantageous when coupled with the use of synthetic salts.

  9. Alternative Evaluation Designs for Data-Centered Technology-Based Geoscience Education Projects

    Science.gov (United States)

    Zalles, D. R.

    2012-12-01

    This paper will present different strategies for how to evaluate contrasting K-12 geoscience classroom-based interventions with different goals, leveraging the first author's experiences as principal investigator of four NSF and NASA-funded geoscience education projects. Results will also be reported. Each project had its own distinctive features but all had in common the broad goal of bringing to high school classrooms uses of real place-based geospatial data to study the relationships of Earth system phenomena to climate change and sustainability. The first project's goal was to produce templates and exemplars for curriculum and assessment designs around studying contrasting geoscience topics with different data sets and forms of data representation. The project produced a near transfer performance assessment task in which students who studied climate trends in Phoenix turned their attention to climate in Chicago. The evaluation looked at the technical quality of the assessment instrument as measured by inter-rater reliability. It then analyzed the assessment results against student responses to the instructional tasks about Phoenix. The evaluation proved useful in pinpointing areas of student strength and weakness on different inquiry tasks, from simple map interpretation to analysis of contrasting claims about what the data indicate. The goal of the second project was to produce an exemplar curriculum unit that bridges Western science and traditional American Indian ecological knowledge for student learning and skill building about local environmental sustainability issues. The evaluation looked at the extent to which Western and traditional perspectives were incorporated into the design of the curriculum. The curriculum was not constructed with a separate assessment, yet evidence centered design was utilized to extrapolate from the exemplar unit templates for future instructional and assessment tasks around other places, other sustainability problems, and

  10. A Survey on Underwater Acoustic Sensor Network Routing Protocols

    Directory of Open Access Journals (Sweden)

    Ning Li

    2016-03-01

    Full Text Available Underwater acoustic sensor networks (UASNs have become more and more important in ocean exploration applications, such as ocean monitoring, pollution detection, ocean resource management, underwater device maintenance, etc. In underwater acoustic sensor networks, since the routing protocol guarantees reliable and effective data transmission from the source node to the destination node, routing protocol design is an attractive topic for researchers. There are many routing algorithms have been proposed in recent years. To present the current state of development of UASN routing protocols, we review herein the UASN routing protocol designs reported in recent years. In this paper, all the routing protocols have been classified into different groups according to their characteristics and routing algorithms, such as the non-cross-layer design routing protocol, the traditional cross-layer design routing protocol, and the intelligent algorithm based routing protocol. This is also the first paper that introduces intelligent algorithm-based UASN routing protocols. In addition, in this paper, we investigate the development trends of UASN routing protocols, which can provide researchers with clear and direct insights for further research.

  11. A Survey on Underwater Acoustic Sensor Network Routing Protocols.

    Science.gov (United States)

    Li, Ning; Martínez, José-Fernán; Meneses Chaus, Juan Manuel; Eckert, Martina

    2016-03-22

    Underwater acoustic sensor networks (UASNs) have become more and more important in ocean exploration applications, such as ocean monitoring, pollution detection, ocean resource management, underwater device maintenance, etc. In underwater acoustic sensor networks, since the routing protocol guarantees reliable and effective data transmission from the source node to the destination node, routing protocol design is an attractive topic for researchers. There are many routing algorithms have been proposed in recent years. To present the current state of development of UASN routing protocols, we review herein the UASN routing protocol designs reported in recent years. In this paper, all the routing protocols have been classified into different groups according to their characteristics and routing algorithms, such as the non-cross-layer design routing protocol, the traditional cross-layer design routing protocol, and the intelligent algorithm based routing protocol. This is also the first paper that introduces intelligent algorithm-based UASN routing protocols. In addition, in this paper, we investigate the development trends of UASN routing protocols, which can provide researchers with clear and direct insights for further research.

  12. Lawrence Livermore National Laboratory Decontamination and Waste Treatment Facility: Documentation of impact analysis for design alternatives presented in the Draft Environmental Impact Statement

    International Nuclear Information System (INIS)

    1988-05-01

    Lawrence Livermore National Laboratory (LLNL) is proposing to construct and operate a new Decontamination and Waste Treatment Facility (DWTF). The proposed DWTF would replace the existing Hazardous Waste Management (HWM) facilities at LLNL. The US Department of Energy (DOE) is preparing a Draft Environmental Impact Statement (DEIS) to assess the environmental consequences of the proposed DWTF and its alternatives. This report presents the assumptions, methodologies, and analyses used to estimate the waste flows, air emissions, ambient air quality impacts, and public health risks that are presented in the DEIS. Two DWTF design alternatives (Level I and Level II) have been designated as reasonable design alternatives considering available technologies, environmental regulations, and current and future LLNL waste generation. Both design alternatives would include new, separate radioactive and nonradioactive liquid waste treatment systems, a solidification unit, a new decontamination facility, storage and treatment facilities for reactive materials, a radioactive waste storage area, receiving and classification areas, and a uranium burn pan. The Level I design alternative would include a controlled-air incinerator system, while the Level II design alternative would include a rotary kiln incinerator system. 43 refs., 4 figs., 24 tabs

  13. Highway and interline transportation routing models

    International Nuclear Information System (INIS)

    Joy, D.S.; Johnson, P.E.

    1994-01-01

    The potential impacts associated with the transportation of hazardous materials are important issues to shippers, carriers, and the general public. Since transportation routes are a central characteristic in most of these issues, the prediction of likely routes is the first step toward the resolution of these issues. In addition, US Department of Transportation requirements (HM-164) mandate specific routes for shipments of highway controlled quantities of radioactive materials. In response to these needs, two routing models have been developed at Oak Ridge National Laboratory under the sponsorship of the U.S. Department of Energy (DOE). These models have been designated by DOE's Office of Environmental Restoration and Waste Management, Transportation Management Division (DOE/EM) as the official DOE routing models. Both models, HIGHWAY and INTERLINE, are described

  14. DETERMINING BICYCLE ROUTE PRIORITIES: THE KOREAN EXPERIENCE

    OpenAIRE

    Woo Hoon Jeon; ChoongHeon Yang

    2017-01-01

    This study proposes a feasible methodology for prioritizing alternative bicycle routes which are a key to supporting a national bicycle road construction plan. The procedure facilitates consideration of the differing characteristics of bicycle and vehicular traffic. This can be efficiently employed; 1) when future bicycle demand forecasts are considered unreliable due to several reasons such as insufficient data and a wide range of alternative paths for bicycle traffic, and 2) when policy jud...

  15. Nudging socially isolated people towards well-being with the 'Happiness Route': design of a randomized controlled trial for the evaluation of a happiness-based intervention.

    Science.gov (United States)

    Weiss, Laura A; Westerhof, Gerben J; Bohlmeijer, Ernst T

    2013-09-20

    The Happiness Route is an innovative intervention that uses a happiness-based approach for people with an accumulation of risk factors for low well-being: socially isolated people with health impairments and a low socioeconomic status. The goal of this intervention is to improve well-being by engaging participants in intrinsically motivated activities with methods from positive psychology. We hypothesize that the primary outcome measure, emotional, social and psychological well-being of participants of the Happiness Route, will increase in comparison to the traditional and commonly-used problem-based approach. Secondary outcome measures are health-related quality of life, psychosocial functioning and health care consumption. Participants will be socially isolated people with health problems and a low socioeconomic status. Participants will be recruited in ten Dutch communities and candidates will be signed up by intermediaries, professionals from the health and social sector. Randomly assigned, half of the participants will follow the Happiness Route and half of the participants will follow the active, problem-focused control group 'Customized Care'. In total, 256 participants will be included. In both conditions, participants will receive counseling sessions from trained counselors. In the control group, participants will talk about their problems and the care they get and counselors help to optimize their care. In the Happiness Route, the counselor ask questions such as "How do you want to live your life?". The intervention helps people to find their 'passion', i.e., a positive goal-engaged and intrinsically motivated activity. It enables them to follow their passion through by a once-only personal happiness budget (maximal €500). We use well-validated and reliable questionnaires to measure primary and secondary outcome measures at baseline, directly after the intervention and at a nine-month follow-up. Shortcomings of earlier intervention studies in positive

  16. On Designing Thermal-Aware Localized QoS Routing Protocol for in-vivo Sensor Nodes in Wireless Body Area Networks

    OpenAIRE

    Monowar, Muhammad Mostafa; Bajaber, Fuad

    2015-01-01

    In this paper, we address the thermal rise and Quality-of-Service (QoS) provisioning issue for an intra-body Wireless Body Area Network (WBAN) having in-vivo sensor nodes. We propose a thermal-aware QoS routing protocol, called TLQoS, that facilitates the system in achieving desired QoS in terms of delay and reliability for diverse traffic types, as well as avoids the formation of highly heated nodes known as hotspot(s), and keeps the temperature rise along the network to an acceptable level....

  17. Study of the liquid-film-forming apparatus as an alternative aeration system: design criteria and operating condition.

    Science.gov (United States)

    Hongprasith, Narapong; Imai, Tsuyoshi; Painmanakul, Pisut

    2017-06-01

    Aeration is an important factor in aquaculture systems because it is a vital condition for all organisms that live in water and respire aerobically. Generally, mechanical surface aerators are widely used in Thailand due to their advantage for increasing dissolved oxygen (DO) and for their horizontal mixing of aquaculture ponds with large surface areas. However, these systems still have some drawbacks, primarily the low oxygen transfer efficiency (OTE) and energy. Regarding this issue, alternative aeration systems should be studied and applied. Therefore, this research aims to study the aeration mechanism obtained by the diffused-air aeration combined with a liquid-film-forming apparatus (LFFA). The effect of gas flow rates, types, and patterns of aerator installation were investigated in an aquaculture pond of 10 m × 10 m × 1.5 m. The analytical parameters were volumetric mass transfer coefficient (k L a), OTE, and aeration efficiency (AE). From the results, the '4-D' with partitions was proposed as the suitable pattern for the LFFA installation. The advantage could be obtained from high energy performance with 1.2 kg/kW h of AE. Then, the operation conditions can be applied as a design guideline for this alternative aeration system in the aquaculture ponds.

  18. Scenemash: multimodal route summarization for city exploration

    NARCIS (Netherlands)

    Berg, J. van den; Rudinac, S.; Worring, M.

    2016-01-01

    The potential of mining tourist information from social multimedia data gives rise to new applications offering much richer impressions of the city. In this paper we propose Scenemash, a system that generates multimodal summaries of multiple alternative routes between locations in a city. To get

  19. Hanson Russian River Ponds floodplain restoration: Feasibility study and conceptual design; Appendix G: Physical evaluation of the restoration alternatives

    Science.gov (United States)

    McDonald, Richard R.; Nelson, Jonathan M.

    2016-01-01

    Appendix G: Hanson Russian River Ponds Floodplain Restoration: Feasibility Study and Conceptual Design |G-1Appendix GPhysical Evaluation of the Restoration AlternativesRichard McDonald and Jonathan Nelson, PhDU.S. Geological Survey Geomorphology and Sediment Transport Laboratory, Golden, ColoradoIntroductionTo assess the relative and overall impacts of the scenarios proposed in Chapters 7 and 9,(Stage I-A–I-D and Stage II-A –II-E), each of the topographic configurations were evaluated over a range of flows. Thisevaluation was carried out using computational flow modeling tools available in the iRIC public-domain river modeling interface (www.i-ric.org, Nelsonet al.in press). Using the iRIC modeling tools described in more detail below, basic hydraulic computations of water-surface elevation, velocity, shear stress, and other hydraulic variables were carried out for the alternatives in the reach surrounding the project area, from the confluence of Dry Creek upstream to the Wohler road bridge downstream, for the full range of observed flows. This methodology allows comparison of the current channel configuration with the proposed alternatives in terms of inundation period and frequency, depth, water velocity, and other hydraulic information. By integrating this kind of information over the reach of interest and the flow record, critical metrics assessing the impacts of various topographic modifications can be compared to those same metrics for the existing condition or other modification scenarios. In addition, because the iRIC tools include predictions of sediment mobility, suspension of fines, and the potential evolution of the land surface in response to flow, these methods provide evaluation of sediment transport, stability of current and proposed surfaces, and evaluation of how these surfaces might evolve into the future. This hydraulic and sediment transport information is critically important for understanding theimpacts of various proposed alternatives on

  20. Large graph visualization of millions of connections in the CERN control system network traffic: analysis and design of routing and firewall rules with a new approach

    CERN Document Server

    Gallerani, Luigi

    2015-01-01

    Abstract The CERN Technical Network (TN) TN was intended to be a network for accelerator and infrastructure operations. However, today, more than 60 million IP packets are routed every hour between the General Purpose Network (GPN) and the TN, involving more than 6000 different hosts. In order to improve the security of the accelerator control system, it is fundamental to understand the network traffic between the two networks and to define new appropriate routing and firewall rules without impacting operations. The complexity and huge size of the infrastructure and the number of protocols and services involved, have discouraged for years any attempt to understand and control the network traffic between the GPN and the TN. In this paper, we show a new way to solve the problem graphically. Combining the network traffic analysis with the use of large graph visualization algorithms we produced usable 2D large color topology maps of the network identifying the inter-relations of the control system machines and s...

  1. Understanding individual routing behaviour.

    Science.gov (United States)

    Lima, Antonio; Stanojevic, Rade; Papagiannaki, Dina; Rodriguez, Pablo; González, Marta C

    2016-03-01

    Knowing how individuals move between places is fundamental to advance our understanding of human mobility (González et al. 2008 Nature 453, 779-782. (doi:10.1038/nature06958)), improve our urban infrastructure (Prato 2009 J. Choice Model. 2, 65-100. (doi:10.1016/S1755-5345(13)70005-8)) and drive the development of transportation systems. Current route-choice models that are used in transportation planning are based on the widely accepted assumption that people follow the minimum cost path (Wardrop 1952 Proc. Inst. Civ. Eng. 1, 325-362. (doi:10.1680/ipeds.1952.11362)), despite little empirical support. Fine-grained location traces collected by smart devices give us today an unprecedented opportunity to learn how citizens organize their travel plans into a set of routes, and how similar behaviour patterns emerge among distinct individual choices. Here we study 92 419 anonymized GPS trajectories describing the movement of personal cars over an 18-month period. We group user trips by origin-destination and we find that most drivers use a small number of routes for their routine journeys, and tend to have a preferred route for frequent trips. In contrast to the cost minimization assumption, we also find that a significant fraction of drivers' routes are not optimal. We present a spatial probability distribution that bounds the route selection space within an ellipse, having the origin and the destination as focal points, characterized by high eccentricity independent of the scale. While individual routing choices are not captured by path optimization, their spatial bounds are similar, even for trips performed by distinct individuals and at various scales. These basic discoveries can inform realistic route-choice models that are not based on optimization, having an impact on several applications, such as infrastructure planning, routing recommendation systems and new mobility solutions. © 2016 The Author(s).

  2. Catalyst-Controlled Stereoselective Olefin Metathesis as a Principal Strategy in Multi-Step Synthesis Design. A Concise Route to (+)-Neopeltolide**

    Science.gov (United States)

    Yu, Miao; Schrock, Richard R.

    2014-01-01

    Mo-, W- and Ru-based complexes that control the stereochemical outcome of olefin metathesis reactions have been recently introduced. However, the complementary nature of these systems through their combined use in multistep complex molecule synthesis has not been illustrated. Here, we disclose a concise diastereo- and enantioselective route that furnishes the anti-proliferative natural product neopeltolide. Catalytic transformations are employed to address every stereochemical issue. Among the featured processes are an enantioselective ring-opening/cross-metathesis promoted by a Mo monopyrrolide aryloxide (MAP) complex and a macrocyclic ring-closing metathesis affording a trisubstituted alkene catalyzed by a Mo bis-aryloxide species. Furthermore, Z-selective cross-metathesis reactions, facilitated by Mo and Ru complexes, have been employed in stereoselective synthesis of the acyclic dienyl moiety of the target molecule. PMID:25377347

  3. Dual-Frequency Alternating Current Designer Waveform for Reliable Voltammetric Determination of Electrode Kinetics Approaching the Reversible Limit.

    Science.gov (United States)

    Li, Jiezhen; Bentley, Cameron L; Bond, Alan M; Zhang, Jie

    2016-02-16

    Alternating current (ac) voltammetry provides access to faster electrode kinetics than direct current (dc) methods. However, difficulties in ac and other methods arise when the heterogeneous electron-transfer rate constant (k(0)) approaches the reversible limit, because the voltammetric characteristics become insensitive to electrode kinetics. Thus, in this near-reversible regime, even small uncertainties associated with bulk concentration (C), diffusion coefficient (D), electrode area (A), and uncompensated resistance (Ru) can lead to significant systematic error in the determination of k(0). In this study, we have introduced a kinetically sensitive dual-frequency designer waveform into the Fourier-transformed large-amplitude alternating current (FTAC) voltammetric method that is made up of two sine waves having the same amplitude but with different frequencies (e.g., 37 and 615 Hz) superimposed onto a dc ramp to quantify the close-to-reversible Fc(0/+) process (Fc = ferrocene) in two nonhaloaluminate ionic liquids. The concept is that from a single experiment the lower-frequency data set, collected on a time scale where the target process is reversible, can be used as an internal reference to calibrate A, D, C, and Ru. These calibrated values are then used to calculate k(0) from analysis of the harmonics of the higher-frequency data set, where the target process is quasi-reversible. With this approach, k(0) values of 0.28 and 0.11 cm·s(-1) have been obtained at a 50 μm diameter platinum microdisk electrode for the close-to-diffusion-controlled Fc(0/+) process in two ionic liquids, 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide and 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide, respectively.

  4. A Synthesis of Relevant Literature on the Development of Emotional Competence: Implications for Design of Augmentative and Alternative Communication Systems.

    Science.gov (United States)

    Na, Ji Young; Wilkinson, Krista; Karny, Meredith; Blackstone, Sarah; Stifter, Cynthia

    2016-08-01

    Emotional competence refers to the ability to identify, respond to, and manage one's own and others' emotions. Emotional competence is critical to many functional outcomes, including making and maintaining friends, academic success, and community integration. There appears to be a link between the development of language and the development of emotional competence in children who use speech. Little information is available about these issues in children who rely on augmentative and alternative communication (AAC). In this article, we consider how AAC systems can be designed to support communication about emotions and the development of emotional competence. Because limited research exists on communication about emotions in a context of aided AAC, theory and research from other fields (e.g., psychology, linguistics, child development) is reviewed to identify key features of emotional competence and their possible implications for AAC design and intervention. The reviewed literature indicated that the research and clinical attention to emotional competence in children with disabilities is encouraging. However, the ideas have not been considered specifically in the context of aided AAC. On the basis of the reviewed literature, we offer practical suggestions for system design and AAC use for communication about emotions with children who have significant disabilities. Three key elements of discussing emotions (i.e., emotion name, reason, and solution) are suggested for inclusion in order to provide these children with opportunities for a full range of discussion about emotions. We argue that supporting communication about emotions is as important for children who use AAC as it is for children who are learning speech. This article offers a means to integrate information from other fields for the purpose of enriching AAC supports.

  5. Transportation routing analysis geographic information system -- TRAGIS, a multimodal transportation routing tool

    International Nuclear Information System (INIS)

    Johnson, P.E.

    1995-01-01

    Over 15 years ago, Oak Ridge National Laboratory (ORNL) developed two transportation routing models: HIGHWAY, which predicts truck transportation routes, and INTERLINE, which predicts rail transportation routes. Subsequent modifications have been made to enhance each of these models. Some of these changes include population density information for routes, HM-164 routing regulations for highway route controlled quantities of radioactive materials (RAM) truck shipments, and inclusion of waterway routing into INTERLINE. The AIRPORT model, developed 2 years after the HIGHWAY and INTERLINE models, serves as an emergency response tool. This model identifies the nearest airports from a designated location. Currently, the AIRPORT model is inactive. The Transportation Management Division of the US Department of Energy held a Baseline Requirements Assessment Session on the HIGHWAY, INTERLINE, and AIRPORT models in April 1994 to bring together many users of these models and other experts in the transportation routing field to discuss these models and to decide on the capabilities that needed to be added. Of the many needs discussed, the primary one was to have the network databases within a geographic information system (GIS). As a result of the Baseline Requirements Session, the development of a new GIS model has been initiated. This paper will discuss the development of the new Transportation Routing Analysis GIS (TRAGIS) model at ORNL

  6. Routes and Stations

    Data.gov (United States)

    Department of Homeland Security — he Routes_Stations table is composed of fixed rail transit systems within the Continental United States, Alaska, Hawaii, the District of Columbia, and Puerto Rico....

  7. Class network routing

    Science.gov (United States)

    Bhanot, Gyan [Princeton, NJ; Blumrich, Matthias A [Ridgefield, CT; Chen, Dong [Croton On Hudson, NY; Coteus, Paul W [Yorktown Heights, NY; Gara, Alan G [Mount Kisco, NY; Giampapa, Mark E [Irvington, NY; Heidelberger, Philip [Cortlandt Manor, NY; Steinmacher-Burow, Burkhard D [Mount Kisco, NY; Takken, Todd E [Mount Kisco, NY; Vranas, Pavlos M [Bedford Hills, NY

    2009-09-08

    Class network routing is implemented in a network such as a computer network comprising a plurality of parallel compute processors at nodes thereof. Class network routing allows a compute processor to broadcast a message to a range (one or more) of other compute processors in the computer network, such as processors in a column or a row. Normally this type of operation requires a separate message to be sent to each processor. With class network routing pursuant to the invention, a single message is sufficient, which generally reduces the total number of messages in the network as well as the latency to do a broadcast. Class network routing is also applied to dense matrix inversion algorithms on distributed memory parallel supercomputers with hardware class function (multicast) capability. This is achieved by exploiting the fact that the communication patterns of dense matrix inversion can be served by hardware class functions, which results in faster execution times.

  8. A Clustering Routing Protocol for Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Jinke Huang

    2016-01-01

    Full Text Available The dynamic topology of a mobile ad hoc network poses a real challenge in the design of hierarchical routing protocol, which combines proactive with reactive routing protocols and takes advantages of both. And as an essential technique of hierarchical routing protocol, clustering of nodes provides an efficient method of establishing a hierarchical structure in mobile ad hoc networks. In this paper, we designed a novel clustering algorithm and a corresponding hierarchical routing protocol for large-scale mobile ad hoc networks. Each cluster is composed of a cluster head, several cluster gateway nodes, several cluster guest nodes, and other cluster members. The proposed routing protocol uses proactive protocol between nodes within individual clusters and reactive protocol between clusters. Simulation results show that the proposed clustering algorithm and hierarchical routing protocol provide superior performance with several advantages over existing clustering algorithm and routing protocol, respectively.

  9. Characterization of Static/Dynamic Topological Routing For Grid Networks

    DEFF Research Database (Denmark)

    Gutierrez Lopez, Jose Manuel; Cuevas, Ruben; Riaz, M. Tahir

    2009-01-01

    Grid or 2D Mesh structures are becoming one of the most attractive network topologies to study. They can be used in many different fields raging from future broadband networks to multiprocessors structures. In addition, the high requirements of future services and applications demand more flexible...... and adaptive networks. Topological routing in grid networks is a simple and efficient alternative to traditional routing techniques, e.g. routing tables, and the paper extends this kind of routing providing a "Dynamic" attribute. This new property attempts to improve the overall network performance for future...

  10. Route and fleet design for cyclic inventory routing

    NARCIS (Netherlands)

    Raa, Birger; Dullaert, Wout

    2017-01-01

    This paper presents a novel solution approach for planning cyclic distribution from a single depot to multiple customers with constant, deterministic demand rates. The objective is to minimize the total cost rate consisting of fleet costs, distribution costs from the depot to the customers and

  11. Electromagnetic Design and Losses Analysis of a High-Speed Permanent Magnet Synchronous Motor with Toroidal Windings for Pulsed Alternator

    Directory of Open Access Journals (Sweden)

    Yuan Wan

    2018-03-01

    Full Text Available The configuration of conventional high-speed Permanent Magnet Synchronous Motors (PMSMs is usually long and thin, with overlong axial end winding lengths, which is not suitable for those applications that place severe restrictions on the axial length, such as pulsed alternators. This paper first studied the key design aspects of a flat-structure high-speed PMSM. The toroidal-windings, low-conductivity material of the retaining sleeve, large airgap and segmentation of magnets were studied to reduce the axial length of the motor. The division of the stator and the employment of a non-magnetic outer stator were used to improve overall performance. Then the losses of the prototype were calculated and the factors having an influence on the losses were also investigated, after which, their effects on the total loss were evaluated. The total loss could be effectively reduced by the decrease of strand number of conductors and the division of stator, while only being slightly reduced by epoxy resin pole fillers. Metal-stack pole fillers have the same effect on the reduction of rotor loss as epoxy resin, while maintaining the good thermal-conductivity of metal. In addition, the influence of the carrier frequency of the inverter on the losses was analyzed, and it was found that high carrier frequency was helpful to reduce rotor losses. Finally, a small-scale prototype was manufactured and the experimental results were provided.

  12. Novel design of high voltage pulse source for efficient dielectric barrier discharge generation by using silicon diodes for alternating current

    Science.gov (United States)

    Truong, Hoa Thi; Hayashi, Misaki; Uesugi, Yoshihiko; Tanaka, Yasunori; Ishijima, Tatsuo

    2017-06-01

    This work focuses on design, construction, and optimization of configuration of a novel high voltage pulse power source for large-scale dielectric barrier discharge (DBD) generation. The pulses were generated by using the high-speed switching characteristic of an inexpensive device called silicon diodes for alternating current and the self-terminated characteristic of DBD. The operation started to be powered by a primary DC low voltage power supply flexibly equipped with a commercial DC power supply, or a battery, or DC output of an independent photovoltaic system without transformer employment. This flexible connection to different types of primary power supply could provide a promising solution for the application of DBD, especially in the area without power grid connection. The simple modular structure, non-control requirement, transformer elimination, and a minimum number of levels in voltage conversion could lead to a reduction in size, weight, simple maintenance, low cost of installation, and high scalability of a DBD generator. The performance of this pulse source has been validated by a load of resistor. A good agreement between theoretically estimated and experimentally measured responses has been achieved. The pulse source has also been successfully applied for an efficient DBD plasma generation.

  13. Design study of a 15 kW free-piston Stirling engine-linear alternator for dispersed solar electric power systems

    Science.gov (United States)

    Dochat, G. R.; Chen, H. S.; Bhate, S.; Marusak, T.

    1979-01-01

    A conceptual design of a free piston solar Stirling engine-linear alternator which can be designed and developed to meet the requirements of a near-term solar test bed engine with minimum risks was developed. The conceptual design was calculated to have an overall system efficiency of 38% and provide 15kW electric output. The free piston engine design incorporates features such as gas bearings, close clearance seals, and gas springs. This design is hermetically sealed to provide long life, reliability, and maintenance free operation. An implementation assessment study performed indicates that the free piston solar Stirling engine-linear alternator can be manufactured at a reasonable price cost (direct labor plus material) of $2,500 per engine in production quantities of 25,000 units per year. Opportunity for significant reduction of cost was also identified.

  14. Simulated Annealing Technique for Routing in a Rectangular Mesh Network

    Directory of Open Access Journals (Sweden)

    Noraziah Adzhar

    2014-01-01

    Full Text Available In the process of automatic design for printed circuit boards (PCBs, the phase following cell placement is routing. On the other hand, routing process is a notoriously difficult problem, and even the simplest routing problem which consists of a set of two-pin nets is known to be NP-complete. In this research, our routing region is first tessellated into a uniform Nx×Ny array of square cells. The ultimate goal for a routing problem is to achieve complete automatic routing with minimal need for any manual intervention. Therefore, shortest path for all connections needs to be established. While classical Dijkstra’s algorithm guarantees to find shortest path for a single net, each routed net will form obstacles for later paths. This will add complexities to route later nets and make its routing longer than the optimal path or sometimes impossible to complete. Today’s sequential routing often applies heuristic method to further refine the solution. Through this process, all nets will be rerouted in different order to improve the quality of routing. Because of this, we are motivated to apply simulated annealing, one of the metaheuristic methods to our routing model to produce better candidates of sequence.

  15. Optimizing well intervention routes

    Energy Technology Data Exchange (ETDEWEB)

    Paiva, Ronaldo O. [PETROBRAS S.A., Vitoria, ES (Brazil); Schiozer, Denis J.; Bordalo, Sergio N. [Universidade Estadual de Campinas, SP (Brazil). Faculdade de Engenharia Mecanica. Centro de Estudo do Petroleo (CEPETRO)]. E-mail: denis@dep.fem.unicamp.br; bordalo@dep.fem.unicamp.br

    2000-07-01

    This work presents a method for optimizing the itinerary of work over rigs, i.e., the search for the route of minimum total cost, and demonstrates the importance of the dynamics of reservoir behaviour. The total cost of a route includes the rig expenses (transport, assembly and operation), which are functions of time and distances, plus the losses of revenue in wells waiting for the rig, which are also dependent of time. A reservoir simulator is used to evaluate the monetary influence of the well shutdown on the present value of the production curve. Finally, search algorithms are employed to determine the route of minimal cost. The Simulated Annealing algorithm was also successful in optimizing the distribution of a list of wells among different work over rigs. The rational approach presented here is recommended for management teams as a standard procedure to define the priority of wells scheduled for work over. (author)

  16. Routing and scheduling problems

    DEFF Research Database (Denmark)

    Reinhardt, Line Blander

    be that the objects routed have an availability time window and a delivery time window or that locations on the path have a service time window. When routing moving transportation objects such as vehicles and vessels schedules are made in connection with the routing. Such schedules represent the time for the presence......In today’s globalized society, transport contributes to our daily life in many different ways. The production of the parts for a shelf ready product may take place on several continents and our travel between home and work, vacation travel and business trips has increased in distance the last...... couple of decades. To deliver competitive service and price, transportation today needs to be cost effective. A company requiring for things to be shipped will aim at having the freight shipped as cheaply as possible while often satisfying certain time constraints. For the transportation company...

  17. Collective network routing

    Science.gov (United States)

    Hoenicke, Dirk

    2014-12-02

    Disclosed are a unified method and apparatus to classify, route, and process injected data packets into a network so as to belong to a plurality of logical networks, each implementing a specific flow of data on top of a common physical network. The method allows to locally identify collectives of packets for local processing, such as the computation of the sum, difference, maximum, minimum, or other logical operations among the identified packet collective. Packets are injected together with a class-attribute and an opcode attribute. Network routers, employing the described method, use the packet attributes to look-up the class-specific route information from a local route table, which contains the local incoming and outgoing directions as part of the specifically implemented global data flow of the particular virtual network.

  18. An Immune Cooperative Particle Swarm Optimization Algorithm for Fault-Tolerant Routing Optimization in Heterogeneous Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Yifan Hu

    2012-01-01

    Full Text Available The fault-tolerant routing problem is important consideration in the design of heterogeneous wireless sensor networks (H-WSNs applications, and has recently been attracting growing research interests. In order to maintain k disjoint communication paths from source sensors to the macronodes, we present a hybrid routing scheme and model, in which multiple paths are calculated and maintained in advance, and alternate paths are created once the previous routing is broken. Then, we propose an immune cooperative particle swarm optimization algorithm (ICPSOA in the model to provide the fast routing recovery and reconstruct the network topology for path failure in H-WSNs. In the ICPSOA, mutation direction of the particle is determined by multi-swarm evolution equation, and its diversity is improved by immune mechanism, which can enhance the capacity of global search and improve the converging rate of the algorithm. Then we validate this theoretical model with simulation results. The results indicate that the ICPSOA-based fault-tolerant routing protocol outperforms several other protocols due to its capability of fast routing recovery mechanism, reliable communications, and prolonging the lifetime of WSNs.

  19. Development of a Healthy Urban Route Planner for cyclists and pedestrians in Amsterdam

    Science.gov (United States)

    van der Molen, Michiel; Ligtenberg, Arend; Vreugdenhil, Corne; Steeneveld, Gert-Jan

    2017-04-01

    Cities are hotspots of air pollution and heat stress, the exposure to which results in nuisance, health risks, cost of medication, reduced labour productivity and sick leave for citizens. Yet the air pollution and heat stress are spatially and temporally unevenly distributed over the city, depending on pollutant emissions, street design and atmospheric turbulent mixing and radiation. This spatiotemporal variation allows pedestrians and bikers to choose alternative routes to minimize their exposure, if the distribution is known. In this project, we develop a route planner for bicyclists and pedestrians for Amsterdam (NL), that proposes routes and departure times based on model simulations of weather and air quality. We use the WRF-Chem atmosphere and air quality model at unprecedented grid spacing of 100-m (Ronda et al, 2015, Super et al, 2016), with an underlying urban canopy model and NOx and PM10 emissions. The emissions by traffic are calculated based on observed traffic intensities and emission factors. An urban land use map will characterize urban density and street configuration to estimate urban heat storage (Attema et al, 2015). WRF-Chem runs will be issued daily for a lead time of 48 hours, resulting in forecast maps of temperature and pollutant concentrations that will be uniquely expressed in a metric that combines both threats. The hourly fields of this metric are provided to the route planner based on the open source routing library pgRouting to identify the more healthy routes on the route network of Amsterdam. The objectives of the healthy urban route planner are to raise awareness of heat and air quality issues in Amsterdam, to provide an innovative adaptation tool for citizens and tourists, to locate the most important bottlenecks in (the exposure to) air pollution and heat stress, and ultimately to test the readiness of the travellers to use the information and adapt the route. We expect to particularly target a group of lung- and cardiovascular

  20. Routing algorithms in networks-on-chip

    CERN Document Server

    Daneshtalab, Masoud

    2014-01-01

    This book provides a single-source reference to routing algorithms for Networks-on-Chip (NoCs), as well as in-depth discussions of advanced solutions applied to current and next generation, many core NoC-based Systems-on-Chip (SoCs). After a basic introduction to the NoC design paradigm and architectures, routing algorithms for NoC architectures are presented and discussed at all abstraction levels, from the algorithmic level to actual implementation.  Coverage emphasizes the role played by the routing algorithm and is organized around key problems affecting current and next generation, many-core SoCs. A selection of routing algorithms is included, specifically designed to address key issues faced by designers in the ultra-deep sub-micron (UDSM) era, including performance improvement, power, energy, and thermal issues, fault tolerance and reliability.   ·         Provides a comprehensive overview of routing algorithms for Networks-on-Chip and NoC-based, manycore systems; ·         Describe...

  1. The Development of Mini Portable Digester Designs for Domestic and Restaurant Solid Waste Processing to be Clean Biogas as Energy's Alternative to Replace LPG

    International Nuclear Information System (INIS)

    Mansur, A; Janari dan, D; Setiawan, N

    2016-01-01

    Biofuel is developed as an alternative source of second generation energy that could be attained from organic waste. This research is purposed to create applicative and cheap Portable digester unit for society. The design concepts’ screening that was made under considerations of the experts is finally resumed. Design 1 with final weight score of 1, design 2 with final weight score of -1, design 3 with final weight score of 2, design 4 with final weight score 3, design 5 with final weight score of -1, design 6 with final weight score of 0. Accepted designs for further concept assessment are design 1, 2 and 6. The result of concept assessment applies weighting for the scoring. Design 1 resulting 2.67, design 2 results 2.15 while design 3 results 2.52. Design 1 is concluded as the design with biggest result, which is 2.67. Its specification is explained as follows: tank capacity of 60 liters, manual rotating crank pivot, tank's material is plastic with symbol 1, material of axle swivel arm is grey cast iron, 2 mm rotary blades with hole. The experiment 1 contained 23.78% methane and 13.65 carbon dioxide that resulted from content test. (paper)

  2. Reliable Internet Routing

    Science.gov (United States)

    2011-09-01

    subprefixes. We refer to this attack as sub-prefix hijacking. 66 There are other variants of prefix hijacking, such as wormhole [49] attacks. Wormhole attacks...are a countermeasure the adversary can employ against secure routing protocols. Wormhole attacks are not discussed in this chapter because in our

  3. SET-Routes programme

    CERN Multimedia

    Marietta Schupp, EMBL Photolab

    2008-01-01

    Dr Sabine Hentze, specialist in human genetics, giving an Insight Lecture entitled "Human Genetics – Diagnostics, Indications and Ethical Issues" on 23 September 2008 at EMBL Heidelberg. Activities in a achool in Budapest during a visit of Angela Bekesi, Ambassadors for the SET-Routes programme.

  4. Route-specific analysis for radioactive materials transportation

    International Nuclear Information System (INIS)

    1986-01-01

    This report addresses a methodology for route-specific analysis, of which route-selection is one aspect. Identification and mitigation of specific hazards along a chosen route is another important facet of route-specific analysis. Route-selection and route-specific mitigation are two tools to be used in minimizing the risk of radioactive materials transportation and promoting public confidence. Other tools exist to improve the safety of transportation under the Nuclear Waste Policy Act. Selection of a transportation mode and other, non-route-specific measures, such as improved driver training and improved cask designs, are additional tools to minimize transportation risk and promote public confidence. This report addresses the route-specific analysis tool and does not attempt to evaluate its relative usefulness as compared to other available tools. This report represents a preliminary attempt to develop a route-specific analysis methodlogy. The Western Interstate Energy Board High-Level Waste Committee has formed a Route-Specific Analysis Task Force which will build upon the methodology proposed in this Staff Report. As western states continue to investigate route-specific analysis issues, it is expected that the methodology will evolve into a more refined product representing the views of a larger group of interested parties in the West

  5. Clean air program : design guidelines for bus transit systems using electric and hybrid electric propulsion as an alternative fuel

    Science.gov (United States)

    2003-03-01

    The use of alternative fuels to power transit buses is steadily increasing. Several fuels, including : Compressed Natural Gas (CNG), Liquefied Natural Gas (LNG), Liquefied Petroleum Gas (LPG), and : Methanol/Ethanol, are already being used. At presen...

  6. Performance Evaluation of the WSN Routing Protocols Scalability

    Directory of Open Access Journals (Sweden)

    L. Alazzawi

    2008-01-01

    Full Text Available Scalability is an important factor in designing an efficient routing protocol for wireless sensor networks (WSNs. A good routing protocol has to be scalable and adaptive to the changes in the network topology. Thus scalable protocol should perform well as the network grows larger or as the workload increases. In this paper, routing protocols for wireless sensor networks are simulated and their performances are evaluated to determine their capability for supporting network scalability.

  7. A Comparative Study of Various Routing Protocols in VANET

    OpenAIRE

    Kumar, Rakesh; Dave, Mayank

    2011-01-01

    Vehicular Ad Hoc Networks (VANET) is a subclass of Mobile ad hoc networks which provides a distinguished approach for Intelligent Transport System (ITS). The survey of routing protocols in VANET is important and necessary for smart ITS. This paper discusses the advantages / disadvantages and the applications of various routing protocols for vehicular ad hoc networks. It explores the motivation behind the designed, and traces the evolution of these routing protocols. F inally the paper conclud...

  8. Design and simulations of a spectral efficient optical code division multiple access scheme using alternated energy differentiation and single-user soft-decision demodulation

    Science.gov (United States)

    A. Garba, Aminata

    2017-01-01

    This paper presents a new approach to optical Code Division Multiple Access (CDMA) network transmission scheme using alternated amplitude sequences and energy differentiation at the transmitters to allow concurrent and secure transmission of several signals. The proposed system uses error control encoding and soft-decision demodulation to reduce the multi-user interference at the receivers. The design of the proposed alternated amplitude sequences, the OCDMA energy modulators and the soft decision, single-user demodulators are also presented. Simulation results show that the proposed scheme allows achieving spectral efficiencies higher than several reported results for optical CDMA and much higher than the Gaussian CDMA capacity limit.

  9. Roots and routes

    DEFF Research Database (Denmark)

    Christensen, Ann-Dorte; Jensen, Sune Qvotrup

    2011-01-01

    This article is about transnational migrants, how they construct belonging to ‘new’ places where they have arrived, and how the feelings of belonging to their places of origin change when they go back. The theoretical part of the article outlines the relationship between migration and belonging...... arguing that there is a dynamic interplay between roots and routes in people's lives. The empirical point of departure is narratives about roots and routes by ethnic minorities settled in Aalborg East, an underprivileged neighbourhood in northern Denmark. One of the main findings is a gap between....... A somewhat paradoxical finding is that it appears to be more difficult for transnational migrants to maintain their roots in the country of origin when they go back than it was to establish new roots in the host country...

  10. Electronic route information panels (DRIPs).

    NARCIS (Netherlands)

    2008-01-01

    Also in the Netherlands, the term Dynamic Route Information Panel (DRIP) is used for an electronic route information panel. A DRIP usually indicates whether there are queues on the various routes to a particular destination and how long they are. On certain locations DRIPS also give the estimated

  11. Stochastic vehicle routing with recourse

    DEFF Research Database (Denmark)

    Gørtz, Inge Li; Nagarajan, Viswanath; Saket, Rishi

    2012-01-01

    We study the classic Vehicle Routing Problem in the setting of stochastic optimization with recourse. StochVRP is a two-stage problem, where demand is satisfied using two routes: fixed and recourse. The fixed route is computed using only a demand distribution. Then after observing the demand inst...

  12. Cross-infrastructure learnings for alternative bridge system designs : a case study on the hybrid composite bridge system.

    Science.gov (United States)

    2015-04-30

    The hybrid composite beam (HCB) technology has been presented as a system for short and medium span beam bridges as an alternative to traditional materials such as concrete and steel. A HCB consists of a concrete tied arch encased in a fiber-reinforc...

  13. Method and apparatus for routing data in an inter-nodal communications lattice of a massively parallel computer system by routing through transporter nodes

    Science.gov (United States)

    Archer, Charles Jens; Musselman, Roy Glenn; Peters, Amanda; Pinnow, Kurt Walter; Swartz, Brent Allen; Wallenfelt, Brian Paul

    2010-11-16

    A massively parallel computer system contains an inter-nodal communications network of node-to-node links. An automated routing strategy routes packets through one or more intermediate nodes of the network to reach a destination. Some packets are constrained to be routed through respective designated transporter nodes, the automated routing strategy determining a path from a respective source node to a respective transporter node, and from a respective transporter node to a respective destination node. Preferably, the source node chooses a routing policy from among multiple possible choices, and that policy is followed by all intermediate nodes. The use of transporter nodes allows greater flexibility in routing.

  14. Clean air program : design guidelines for bus transit systems using compressed natural gas as an alternative fuel

    Science.gov (United States)

    1996-06-01

    This report documents design guidelines for the safe use of Compressed Natural Gas (CNG). The report is designed to provide guidance, information on safe industry practices, applicable national codes and standards, and reference data that transit age...

  15. An inventory location routing model with environmental considerations

    Directory of Open Access Journals (Sweden)

    Lerhlaly Sanaa

    2017-01-01

    Full Text Available In this work we consider an integrated Inventory Location Routing problem ILRP. The objective is to select depots to open, the routes to perform distribution from the capacitated depots to the clients by a homogeneous fleet of vehicles and over a multi-period planning horizon. To solve the problem, an exact model is designed in order to minimize the total cost (location, routing and inventory and the routing CO2 emissions, while respecting transport and storage constraints for a hazardous material. We have also studied an industrial real case to illustrate the problem.

  16. 14 CFR 71.11 - Air Traffic Service (ATS) routes.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Air Traffic Service (ATS) routes. 71.11 Section 71.11 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE DESIGNATION OF CLASS A, B, C, D, AND E AIRSPACE AREAS; AIR TRAFFIC SERVICE ROUTES; AND REPORTING POINTS § 71.11 Air Traffic Service ...

  17. k-Shortest routing of trains on shunting yards

    NARCIS (Netherlands)

    Riezebos, Jan; van Wezel, Wout

    2009-01-01

    We consider the problem of designing algorithmic support for k-best routing decisions in train shunting scheduling. A study at the Netherlands Railways revealed that planners like to interact with the solution process of finding suitable routes. Two types of interaction were required: the

  18. Effect of Different Routes of Vitamin/Mineral premix Administration ...

    African Journals Online (AJOL)

    An experiment was conducted to determine the best route of vitamin/mineral premix administration to broilers using a completely randomized design. The routes of administrations were through formulated diets, daily in drinking water, and daily mixing in feed ration. Histological examination of the liver did not reveal any ...

  19. Selection of optimal variant route based on dynamic fuzzy GRA

    Directory of Open Access Journals (Sweden)

    Jalil Heidary Dahooie

    2018-09-01

    Full Text Available Given the high costs of construction and maintenance, an optimum design methodology is one of the most important steps towards the development of transportation infrastructure, especially freeways. However, the effects of different variables on the decision-making process to find an optimal variant have caused the choice to become a very difficult and professional task for decision makers. So, the current paper aims to determine the optimal variant route for Isfahan-Shiraz freeway through MADM approaches. First, evaluation indices for an optimal route variant are derived through literature review and expert panel assessment. Then, a dynamic fuzzy GRA method is used for weightings and optimal route selection. Bases on the results, the road longevity, views of NGOs and route integration are identified as the highest-weighted criteria in route variant prioritization. Further, Route 3 is defined as the priority for the optimal variant for Isfahan–Shiraz freeway, which is the main basis in practice.

  20. A comparative view of routing protocols for underwater wireless sensor networks

    NARCIS (Netherlands)

    Bayrakdar, Y.; Meratnia, Nirvana; Kantarci, Aylin

    2011-01-01

    Design of efficient routing protocols for underwater sensor networks is challenging because of the distinctive characteristics of the water medium. Currently, many routing protocols are available for terrestrial wireless sensor networks. However, specific properties of underwater medium such as

  1. Economic and quality of life impacts of route 21 freeway construction : final report, October 2009.

    Science.gov (United States)

    2009-10-01

    Opened to traffic in December 2000, the missing section of the Route 21 Freeway in Clifton : and Passaic (Hope Ave. to the Route 46 Interchange) was designed utilizing the equivalent to : the Context Sensitive Solutions (CSS) approach at ...

  2. Dual-Routes and the Cost of Determining Least-Costs

    Directory of Open Access Journals (Sweden)

    Steven Phillips

    2017-11-01

    Full Text Available Theories of cognition that posit complementary dual-route processes afford better fits to the data when each route explains a part of the data not explained by the other route. However, such theories must also explain why each route is invoked, lest one can fit any data set with enough alternatives. One possible explanation is that route selection is based on a least-cost principle: the route that requires fewer cognitive resources (including time relative to the goal at hand. We investigated this explanation with a dual-display version of visual search, where the target could be identified via opposing (easy or hard forms of feature and conjunction search conditions. The data support a contextualized version of the least-cost principle in that the cost of computing least-cost also influences route selection: participants assessed alternatives, but only when the cost of that assessment was relatively low.

  3. Robustness of airline route networks

    Science.gov (United States)

    Lordan, Oriol; Sallan, Jose M.; Escorihuela, Nuria; Gonzalez-Prieto, David

    2016-03-01

    Airlines shape their route network by defining their routes through supply and demand considerations, paying little attention to network performance indicators, such as network robustness. However, the collapse of an airline network can produce high financial costs for the airline and all its geographical area of influence. The aim of this study is to analyze the topology and robustness of the network route of airlines following Low Cost Carriers (LCCs) and Full Service Carriers (FSCs) business models. Results show that FSC hubs are more central than LCC bases in their route network. As a result, LCC route networks are more robust than FSC networks.

  4. FastRoute: An Efficient and High-Quality Global Router

    Directory of Open Access Journals (Sweden)

    Min Pan

    2012-01-01

    Full Text Available Modern large-scale circuit designs have created great demand for fast and high-quality global routing algorithms to resolve the routing congestion at the global level. Rip-up and reroute scheme has been employed by the majority of academic and industrial global routers today, which iteratively resolve the congestion by recreating the routing path based on current congestion. This method is proved to be the most practical routing framework. However, the traditional iterative maze routing technique converges very slowly and easily gets stuck at local optimal solutions. In this work, we propose a very efficient and high-quality global router—FastRoute. FastRoute integrates several novel techniques: fast congestion-driven via-aware Steiner tree construction, 3-bend routing, virtual capacity adjustment, multisource multi-sink maze routing, and spiral layer assignment. These techniques not only address the routing congestion measured at the edges of global routing grids but also minimize the total wirelength and via usage, which is critical for subsequent detailed routing, yield, and manufacturability. Experimental results show that FastRoute is highly effective and efficient to solve ISPD07 and ISPD08 global routing benchmark suites. The results outperform recently published academic global routers in both routability and runtime. In particular, for ISPD07 and ISPD08 global routing benchmarks, FastRoute generates 12 congestion-free solutions out of 16 benchmarks with a speed significantly faster than other routers.

  5. Perancangan dan Analisis Redistribution Routing Protocol OSPF dan EIGRP

    Directory of Open Access Journals (Sweden)

    DWI ARYANTA

    2016-02-01

    and metric compared with the simulation results. The result can be OSPF and EIGRP redistribution process. Value delay redistribution 1% better than OSPF and EIGRP 2-3% under traffic density dependent. In calculating the trace route redistribution is done 2 calculations, the cost for OSPF area and the area of ​​the EIGRP metric. Making primary and alternate paths based on the packet delivery rate and the cost of the smallest metric, it is proved by calculation and simulation. Keywords: OSPF, EIGRP, Redistribution, Delay, Cost, Metric.

  6. The development of a practical pipe auto-routing system in a shipbuilding CAD environment using network optimization

    Science.gov (United States)

    Kim, Shin-Hyung; Ruy, Won-Sun; Jang, Beom Seon

    2013-09-01

    An automatic pipe routing system is proposed and implemented. Generally, the pipe routing design as a part of the shipbuilding process requires a considerable number of man hours due to the complexity which comes from physical and operational constraints and the crucial influence on outfitting construction productivity. Therefore, the automation of pipe routing design operations and processes has always been one of the most important goals for improvements in shipbuilding design. The proposed system is applied to a pipe routing design in the engine room space of a commercial ship. The effectiveness of this system is verified as a reasonable form of support for pipe routing design jobs. The automatic routing result of this system can serve as a good basis model in the initial stages of pipe routing design, allowing the designer to reduce their design lead time significantly. As a result, the design productivity overall can be improved with this automatic pipe routing system

  7. The development of a practical pipe auto-routing system in a shipbuilding CAD environment using network optimization

    Directory of Open Access Journals (Sweden)

    Shin-Hyung Kim

    2013-09-01

    Full Text Available An automatic pipe routing system is proposed and implemented. Generally, the pipe routing design as a part of the shipbuilding process requires a considerable number of man hours due to the complexity which comes from physical and operational constraints and the crucial influence on outfitting construction productivity. Therefore, the automation of pipe routing design operations and processes has always been one of the most important goals for improvements in shipbuilding design. The proposed system is applied to a pipe routing design in the engine room space of a commercial ship. The effectiveness of this system is verified as a reasonable form of support for pipe routing design jobs. The automatic routing result of this system can serve as a good basis model in the initial stages of pipe routing design, allowing the designer to reduce their design lead time significantly. As a result, the design productivity overall can be improved with this automatic pipe routing system.

  8. Sacolas plásticas: destinações sustentáveis e alternativas de substituição Plastic bags: sustainable disposal and alternative routes to their substitution

    Directory of Open Access Journals (Sweden)

    Amélia S. F. e Santos

    2012-01-01

    , including environmental impact assessments of the different alternatives to minimize and/or solve the problems pertaining to the use of plastic bags.

  9. Graphics Translators for Computer-Aided Drafting and Design: Interface Alternatives for the A/E Community.

    Science.gov (United States)

    1984-11-01

    7B. M. Smith and J. Wellington. 8C. Machover , "Status Report: Vendor Update," Presentation to the CAD/CAM Standards Conference on ICES and Alternatives...5/82, (2) telephone contact, (3) third-party source, (4) Machover survey 5/83, (5) press release, (6) ICES Corn- mittee. * 16 Other Capabilities. ICES...Army Construction Engineering Research Laboratory, January 1979). Machover , C., "Status Report: Vendor Update," Presentation to the CAD/CAM Standards

  10. Cognitive Load During Route Selection Increases Reliance on Spatial Heuristics.

    Science.gov (United States)

    Brunyé, Tad T; Martis, Shaina B; Taylor, Holly A

    2017-03-22

    Planning routes from maps involves perceiving the symbolic environment, identifying alternate routes, and applying explicit strategies and implicit heuristics to select an option. Two implicit heuristics have received considerable attention, the southern route preference and initial segment strategy. The current study tested a prediction from decision making theory, that increasing cognitive load during route planning will increase reliance on these heuristics. In two experiments, participants planned routes while under conditions of minimal (0-back) or high (2-back) working memory load. In Experiment 1, we examined how memory load impacts the southern route heuristic. In Experiment 2, we examined how memory load impacts the initial segment heuristic. Results replicated earlier results demonstrating a southern route preference (Experiment 1) and initial segment strategy (Experiment 2), and further demonstrated that evidence for heuristic reliance is more likely under conditions of concurrent working memory load. Furthermore, the extent to which participants maintained efficient route selection latencies in the 2-back condition predicted the magnitude of this effect. Together, results demonstrate that working memory load increases the application of heuristics during spatial decision making, particularly when participants attempt to maintain quick decisions while managing concurrent task demands.

  11. Perancangan dan Analisis Redistribution Routing Protocol OSPF dan EIGRP

    Directory of Open Access Journals (Sweden)

    DWI ARYANTA

    2014-07-01

    OSPF (Open Shortest Path First and EIGRP (Enhanced Interior Gateway Routing Protocol are two routing protocols are widely used in computer networks. Differences between the characteristics of routing protocols pose a problem in the delivery of data packets. Redistribution technique is the solution for communication between routing protocols. By using the software Cisco Packet Tracer 5.3 in this study were made simulating OSPF and EIGRP redistribution linked by technique, then compared its quality with a single EIGRP and OSPF routing protocols. Testing parameters in this study is the value of the time delay and trace route. Value trace route based on direct calculation of cost and metric compared with the simulation results. The result can be OSPF and EIGRP redistribution process. Value delay redistribution 1% better than OSPF and EIGRP 2-3% under traffic density dependent. In calculating the trace route redistribution is done 2 calculations, the cost for OSPF area and the area of the EIGRP metric. Making primary and alternate paths based on the packet delivery rate and the cost of the smallest metric, it is proved by calculation and simulation. Keywords: OSPF, EIGRP, Redistribution, Delay, Cost, Metric.

  12. 3D Building Evacuation Route Modelling and Visualization

    Science.gov (United States)

    Chan, W.; Armenakis, C.

    2014-11-01

    The most common building evacuation approach currently applied is to have evacuation routes planned prior to these emergency events. These routes are usually the shortest and most practical path from each building room to the closest exit. The problem with this approach is that it is not adaptive. It is not responsively configurable relative to the type, intensity, or location of the emergency risk. Moreover, it does not provide any information to the affected persons or to the emergency responders while not allowing for the review of simulated hazard scenarios and alternative evacuation routes. In this paper we address two main tasks. The first is the modelling of the spatial risk caused by a hazardous event leading to choosing the optimal evacuation route for a set of options. The second is to generate a 3D visual representation of the model output. A multicriteria decision making (MCDM) approach is used to model the risk aiming at finding the optimal evacuation route. This is achieved by using the analytical hierarchy process (AHP) on the criteria describing the different alternative evacuation routes. The best route is then chosen to be the alternative with the least cost. The 3D visual representation of the model displays the building, the surrounding environment, the evacuee's location, the hazard location, the risk areas and the optimal evacuation pathway to the target safety location. The work has been performed using ESRI's ArcGIS. Using the developed models, the user can input the location of the hazard and the location of the evacuee. The system then determines the optimum evacuation route and displays it in 3D.

  13. Alternative security

    International Nuclear Information System (INIS)

    Weston, B.H.

    1990-01-01

    This book contains the following chapters: The Military and Alternative Security: New Missions for Stable Conventional Security; Technology and Alternative Security: A Cherished Myth Expires; Law and Alternative Security: Toward a Just World Peace; Politics and Alternative Security: Toward a More Democratic, Therefore More Peaceful, World; Economics and Alternative Security: Toward a Peacekeeping International Economy; Psychology and Alternative Security: Needs, Perceptions, and Misperceptions; Religion and Alternative Security: A Prophetic Vision; and Toward Post-Nuclear Global Security: An Overview

  14. An overview of smart grid routing algorithms

    Science.gov (United States)

    Wang, Junsheng; OU, Qinghai; Shen, Haijuan

    2017-08-01

    This paper summarizes the typical routing algorithm in smart grid by analyzing the communication business and communication requirements of intelligent grid. Mainly from the two kinds of routing algorithm is analyzed, namely clustering routing algorithm and routing algorithm, analyzed the advantages and disadvantages of two kinds of typical routing algorithm in routing algorithm and applicability.

  15. A tree routing protocol for cognitive radio network

    Directory of Open Access Journals (Sweden)

    Mohammed Hashem

    2017-07-01

    Full Text Available Cognitive Radio (CR technology is an agile solution for spectrum congestion and spectrum access utilization problems that result from the legacy fixed spectrum management policies. CR technology can exploit unused licensed band to meet the increasing demand for radio frequency. The routing process faces many challenges in CR Network (CRN such as the absence of centralized infrastructure, the coordination between the routing module and spectrum management module, in addition to the frequent link failure due to the sudden appearance of PUs. In this paper we propose a Tree routing protocol for cognitive radio network (C-TRP that jointly utilizes the tree routing algorithm with a spectrum management module in routing decisions, and also we proposed a new metric used in taking the best route decisions. In addition, we enhance the traditional tree routing algorithm by using a neighbor table technique that speeds up the forwarding data packets. Moreover, we add a robust recovery module to C-TRP to resume the network in case of the link failure. The main motivation in the design of C-TRP is quick data transmission and maximization of date rates. The performance evaluation is carried out in NS2 simulator. The simulation results proved that C-TRP protocol achieves better performance in terms of average “PDR”, “end-to-end delay” and “routing overhead ratio “compared to “CTBR” and “STOD-RP” routing protocols.

  16. ROUTE PLAN DESIGNER FOR TRACTOR GUIDANCE SYSTEMS

    DEFF Research Database (Denmark)

    Sveistrup, Daniel; Jørgensen, Rasmus Nyholm; Green, Ole

    2010-01-01

    in their file formats and operationalrequirements, thereby creating an unnecessary burden for the field trial managers and researchersoperating on different computational platforms such as Windows, Mac or Linux.This paper demonstrates a methodological proof of concept for a software solution for assisting...

  17. Exploration of a capability-focused aerospace system of systems architecture alternative with bilayer design space, based on RST-SOM algorithmic methods.

    Science.gov (United States)

    Li, Zhifei; Qin, Dongliang; Yang, Feng

    2014-01-01

    In defense related programs, the use of capability-based analysis, design, and acquisition has been significant. In order to confront one of the most challenging features of a huge design space in capability based analysis (CBA), a literature review of design space exploration was first examined. Then, in the process of an aerospace system of systems design space exploration, a bilayer mapping method was put forward, based on the existing experimental and operating data. Finally, the feasibility of the foregoing approach was demonstrated with an illustrative example. With the data mining RST (rough sets theory) and SOM (self-organized mapping) techniques, the alternative to the aerospace system of systems architecture was mapping from P-space (performance space) to C-space (configuration space), and then from C-space to D-space (design space), respectively. Ultimately, the performance space was mapped to the design space, which completed the exploration and preliminary reduction of the entire design space. This method provides a computational analysis and implementation scheme for large-scale simulation.

  18. Vertex routing models

    International Nuclear Information System (INIS)

    Markovic, D; Gros, C

    2009-01-01

    A class of models describing the flow of information within networks via routing processes is proposed and investigated, concentrating on the effects of memory traces on the global properties. The long-term flow of information is governed by cyclic attractors, allowing to define a measure for the information centrality of a vertex given by the number of attractors passing through this vertex. We find the number of vertices having a nonzero information centrality to be extensive/subextensive for models with/without a memory trace in the thermodynamic limit. We evaluate the distribution of the number of cycles, of the cycle length and of the maximal basins of attraction, finding a complete scaling collapse in the thermodynamic limit for the latter. Possible implications of our results for the information flow in social networks are discussed.

  19. Future high school teachers' difficulties and alternatives found to planning electromagnetism activities designed for visual handicapped students

    Directory of Open Access Journals (Sweden)

    Eder Pires de Camargo

    2007-03-01

    Full Text Available We report here partial outcomes of a study aimed to verify future High School teachers' performance when, during the development of a called "Teaching Practice" undergraduate course, were asked to plan, elaborate and teach, in classroom situations, electromagnetism topics to a students class which included visual handicapped pupils. Data analyzed show that the main difficulties presented by the future Physics High School teachers are related to the approach to know physics phenomena as dependent of vision and to break with some elements of the traditional pedagogy. By other hand, as alternatives, future teachers showed creativity in order to surpass passive aptitudes related to this educational problem, working out methodological strategies deprived of the relation knowing/seeing, as well as, the work with orality in a physics education context.

  20. Experimental design to measure the anchoring energy on substrate surface by using the alternating-current bridge

    International Nuclear Information System (INIS)

    Hao Hui-Ming; Liu Yao-Yao; Zhang Ping; Zhu Ji-Liang; Ye Wen-Jiang; Cai Ming-Lei; Wang Xiao-Yan

    2017-01-01

    The anchoring property of the substrate surface of liquid crystal cells plays an important role in display and nondisplay fields. This property directly affects the deformation of liquid crystal molecules to change the phase difference through liquid crystal cells. In this paper, a test method based on the alternating-current bridge is proposed to determine the capacitance of liquid crystal cells and thus measure the anchoring energy of the substrate surface. The anchoring energy can be obtained by comparing the capacitance–voltage curves of twisted nematic liquid crystal cells with different anchoring properties in experimental and theoretical results simulated on the basis of Frank elastic theory. Compared with the other methods to determine the anchoring energy, our proposed method requires a simple treatment of liquid crystal cells and allows easy and high-accuracy measurements, thereby expanding the test ideas on the performance parameters of liquid crystal devices. (paper)

  1. Fusion energy for alternate applications: the design of a high temperature falling bed as a long-lived blanket

    International Nuclear Information System (INIS)

    Harkness, S.D.; Stevens, H.C.; Hall, M.M.; Gohar, M.Y.A.; de Paz, J.F.

    1979-01-01

    The high temperature falling bed conceptual design work has consisted of a coordinated effort in neutronics, materials science, thermal hydraulics and mechanical design. The neutronics work has been based on a one-dimensional transport analysis and has been used to scope the implication of blanket dimensions, breeding materials, ceramic pebble material and coolant choice on both tritium breeding capabilities and energy deposition into the high temperature region of the blanket. The materials science effort has concentrated on defining the selection of a particular ceramic material. The thermal hydraulic analysis has been concerned with sizing the heat transfer system and defining the temperature gradients in the high temperature blanket. The mechanical design work has evaluated how such a system might be constructed from the point of view of maintainability and structural support

  2. Design of a high-gain laser diode-array pumped Nd:YAG alternating precessive slab amplifier (APS amplifier)

    Science.gov (United States)

    Coyle, D. B.

    1991-01-01

    In the design of space-qualifiable laser systems for ranging and altimetry, such as NASA's Geodynamic Laser Ranging System (GLRS), the transmitter must be kept small, powerful yet efficient, and must consist of as few components as possible. A novel preamplifier design is examined which requires no external beam steering optics, yielding a compact component with simple alignment procedures. The gains achieved are comparable to multipass zigzag amplifiers using two or more sets of external optics for extra passes through the amplifying medium.

  3. Cyclist safety on bicycle boulevards and parallel arterial routes in Berkeley, California.

    Science.gov (United States)

    Minikel, Eric

    2012-03-01

    This study compares the safety of bicyclists riding on bicycle boulevards to those riding on parallel arterial routes in Berkeley, California. Literature on the impact of motor vehicle traffic characteristics on cyclist safety shows that high motor vehicle speeds and volumes and the presence of heavy vehicles are all detrimental to cyclist safety. This suggests that cyclists may be safer on side streets than on busy arterials. Bicycle boulevards-traffic-calmed side streets signed and improved for cyclist use-purport to offer cyclists a safer alternative to riding on arterials. Police-reported bicycle collision data and manually collected cyclist count data from bicycle boulevards and parallel arterial routes in Berkeley, California from 2003 to 2010 are used to test the hypothesis that Berkeley's bicycle boulevards have lower cyclist collision rates and a lower proportion of bicycle collisions resulting in severe injury. While no significant difference is found in the proportion of collisions that are severe, results show that collision rates on Berkeley's bicycle boulevards are two to eight times lower than those on parallel, adjacent arterial routes. The difference in collision rate is highly statistically significant, unlikely to be caused by any bias in the collision and count data, and cannot be easily explained away by self-selection or safety in numbers. Though the used dataset is limited and the study design is correlational, this study provides some evidence that Berkeley's bicycle boulevards are safer for cyclists than its parallel arterial routes. The results may be suggestive that, more generally, properly implemented bicycle boulevards can provide cyclists with a safer alternative to riding on arterials. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. Solving Real World Problems with Alternate Reality Gaming: Student Experiences in the Global Village Playground Capstone Course Design

    Science.gov (United States)

    Dondlinger, Mary Jo; McLeod, Julie K.

    2015-01-01

    The Global Village Playground (GVP) was a capstone learning experience designed to address institutional assessment needs while providing an integrated and authentic learning experience for students aimed at fostering complex problem solving, as well as critical and creative thinking. In the GVP, students work on simulated and real-world problems…

  5. Rectal route in the 21st Century to treat children.

    Science.gov (United States)

    Jannin, Vincent; Lemagnen, Gilles; Gueroult, Pascale; Larrouture, Denis; Tuleu, Catherine

    2014-06-01

    The rectal route can be considered a good alternative to the oral route for the paediatric population because these dosage forms are neither to be swallowed nor need to be taste-masked. Rectal forms can also be administered in an emergency to unconscious or vomiting children. Their manufacturing cost is low with excipients generally regarded as safe. Some new formulation strategies, including mucoadhesive gels and suppositories, were introduced to increase patient acceptability. Even if recent paediatric clinical studies have demonstrated the equivalence of the rectal route with others, in order to enable the use of this promising route for the treatment of children in the 21st Century, some effort should be focused on informing and educating parents and care givers. This review is the first ever to address all the aforementioned items, and to list all drugs used in paediatric rectal forms in literature and marketed products in developed countries. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. An Efficient Route Maintenance Protocol for Dynamic Bluetooth Networks

    Directory of Open Access Journals (Sweden)

    Sabeen Tahir

    2017-10-01

    Full Text Available Bluetooth is a widespread technology for small wireless networks that permits Bluetooth devices to construct a multi-hop network called scatternet. Routing in multi-hop dynamic Bluetooth network, where a number of masters and bridges exist creates technical hitches. It is observed that frequent link disconnections and a new route construction consume extra system resources that degrade the whole network performance. Therefore, in this paper an Efficient Route Maintenance Protocol for Dynamic Bluetooth Networks (ERMP is proposed that repairs the weak routing paths based on the prediction of weak links and weak devices. The ERMP predicts the weak links through the signal strength and weak devices through low energy levels. During the main route construction, routing masters and bridges keep the information of the Fall Back Devices (FBDs for route maintenance. On the prediction of a weak link, the ERMP activates an alternate link, on the other hand, for a weak device it activates the FBD. The proposed ERMP is compared with some existing closely related protocols, and the simulation results show that the proposed ERMP successfully recovers the weak paths and improves the system performance.

  7. Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome.

    Science.gov (United States)

    Royston, Patrick; Parmar, Mahesh K B

    2013-12-07

    Designs and analyses of clinical trials with a time-to-event outcome almost invariably rely on the hazard ratio to estimate the treatment effect and implicitly, therefore, on the proportional hazards assumption. However, the results of some recent trials indicate that there is no guarantee that the assumption will hold. Here, we describe the use of the restricted mean survival time as a possible alternative tool in the design and analysis of these trials. The restricted mean is a measure of average survival from time 0 to a specified time point, and may be estimated as the area under the survival curve up to that point. We consider the design of such trials according to a wide range of possible survival distributions in the control and research arm(s). The distributions are conveniently defined as piecewise exponential distributions and can be specified through piecewise constant hazards and time-fixed or time-dependent hazard ratios. Such designs can embody proportional or non-proportional hazards of the treatment effect. We demonstrate the use of restricted mean survival time and a test of the difference in restricted means as an alternative measure of treatment effect. We support the approach through the results of simulation studies and in real examples from several cancer trials. We illustrate the required sample size under proportional and non-proportional hazards, also the significance level and power of the proposed test. Values are compared with those from the standard approach which utilizes the logrank test. We conclude that the hazard ratio cannot be recommended as a general measure of the treatment effect in a randomized controlled trial, nor is it always appropriate when designing a trial. Restricted mean survival time may provide a practical way forward and deserves greater attention.

  8. Alternative additives; Alternative additiver

    Energy Technology Data Exchange (ETDEWEB)

    2007-08-15

    In this project a number of industrial and agricultural waste products have been characterised and evaluated in terms of alkali-getter performance. The intended use is for biomass-fired power stations aiming at reducing corrosion or slagging related problems. The following products have been obtained, characterised and evaluated: 1) Brewery draff 2) Danish de-gassed manure 3) Paper sludge 4) Moulding sand 5) Spent bleaching earth 6) Anorthosite 7) Sand 8) Clay-sludge. Most of the above alternative additive candidates are deemed unsuitable due to insufficient chemical effect and/or expensive requirements for pre-treatment (such as drying and transportation). 3 products were selected for full-scale testing: de-gassed manure, spent bleaching earth and clay slugde. The full scale tests were undertaken at the biomass-fired power stations in Koege, Slagelse and Ensted. Spent bleaching earth (SBE) and clay sludge were the only tested additive candidates that had a proven ability to react with KCl, to thereby reduce Cl-concentrations in deposits, and reduce the deposit flux to superheater tubes. Their performance was shown to nearly as good as commercial additives. De-gassed manure, however, did not evaluate positively due to inhibiting effects of Ca in the manure. Furthermore, de-gassed manure has a high concentration of heavy metals, which imposes a financial burden with regard to proper disposal of the ash by-products. Clay-sludge is a wet clay slurring, and drying and transportation of this product entails substantial costs. Spent bleaching does not require much pre-treatment and is therefore the most promising alternative additive. On the other hand, bleaching earth contains residual plant oil which means that a range of legislation relating to waste combustion comes into play. Not least a waste combustion fee of 330 DKK/tonne. For all alternative (and commercial) additives disposal costs of the increase ash by-products represents a significant cost. This is

  9. Automated Flight Routing Using Stochastic Dynamic Programming

    Science.gov (United States)

    Ng, Hok K.; Morando, Alex; Grabbe, Shon

    2010-01-01

    Airspace capacity reduction due to convective weather impedes air traffic flows and causes traffic congestion. This study presents an algorithm that reroutes flights in the presence of winds, enroute convective weather, and congested airspace based on stochastic dynamic programming. A stochastic disturbance model incorporates into the reroute design process the capacity uncertainty. A trajectory-based airspace demand model is employed for calculating current and future airspace demand. The optimal routes minimize the total expected traveling time, weather incursion, and induced congestion costs. They are compared to weather-avoidance routes calculated using deterministic dynamic programming. The stochastic reroutes have smaller deviation probability than the deterministic counterpart when both reroutes have similar total flight distance. The stochastic rerouting algorithm takes into account all convective weather fields with all severity levels while the deterministic algorithm only accounts for convective weather systems exceeding a specified level of severity. When the stochastic reroutes are compared to the actual flight routes, they have similar total flight time, and both have about 1% of travel time crossing congested enroute sectors on average. The actual flight routes induce slightly less traffic congestion than the stochastic reroutes but intercept more severe convective weather.

  10. Science and the media alternative routes in scientific communication

    CERN Document Server

    Bucchi, Massimiano

    1998-01-01

    In the days of global warming and BSE, science is increasingly a public issue. This book provides a theoretical framework which allows us to understand why and how scientists address the general public. The author develops the argument that turning to the public is not simply a response to inaccurate reporting by journalists or to public curiosity, nor a wish to gain recognition and additional funding. Rather, it is a tactic to which the scientific community are pushed by certain "internal" crisis situations. Bucchi examines three cases of scientists turning to the public: the cold fusion case, the COBE/Big Bang issue and Louis Pasteur's public demonstration of the anthrax vaccine, a historical case of "public science." Finally, Bucchi presents his unique model of communications between science and the public, carried out through the media. This is a thoughtful and wide-ranging treatment of complex contemporary issues, touching upon the history and sociology of science, communication and media studies. Bucchi...

  11. Alternative routes for the chemical industry regarding US shale gas

    Energy Technology Data Exchange (ETDEWEB)

    Kneissel, B. [Stratley AG, Koeln (Germany)

    2013-11-01

    Cracking ethane from wet shale gas in North America sets a bench mark to global ethylene production costs. Regarding very attractive ethane prices from extraction of low cost wet shale gas we suggest in North America ethylene production costs will roughly vary between 400 and 600 $/ t. As in other parts of the world, except Middle East, the availability of ethane seems to be more limited other sources for ethylene, such as methane, coal and biomass are investigated. Oxidative coupling of methane (OCM) has its limits and may only lead to competitive production costs for large scale operations. Coal converted to ethylene via calcium carbide and subsequent hydrogenation may hardly be a viable answer. Ethylene derived by dehydration of ethanol from fermentation of corn sugar may be an answer for very low crop prices. Further research on the conversion of methane with emphasis on its industrial implementation as a major carbon resource is recommended. (orig.)

  12. An Alternative Route of Legal Integration: The Community's Railways Policy

    Directory of Open Access Journals (Sweden)

    Christoph Knill

    1998-05-01

    Full Text Available The process of European integration and policy-making is sometimes rather puzzling. On the one hand, it is well documented that with respect to the implementation of European legislation member states tend to do less than they are supposed to do. On the other hand, it is striking that with respect to the implementation of the Council Directive 91/440 on the development of the Community's railways many member states went far beyond the minimum required by the European legislation. We argue that these differing evaluations of implementation success can be traced to different implementation approaches, which may be termed the ‘compliance approach’ and the ‘support-building approach’. While the first is directed at prescribing domestic reforms "from above", the latter aims at triggering European integration within the existing political context at the national level. Here, successful implementation refers to the extent to which European legislation triggers domestic changes by stimulating and strengthening support for European reform ideas at the national level. In this respect, European legislation can influence the domestic arenas in basically three ways: by providing legitimisation for political leadership, concepts for the solution of national problems, and strategic constraints for domestic actors opposing domestic reforms.

  13. A Novel Approach to Fair Routing in Wireless Mesh Networks

    Directory of Open Access Journals (Sweden)

    Määttä Juho

    2009-01-01

    Full Text Available Multiradio wireless mesh network (WMN is a feasible choice for several applications, as routers with multiple network interface cards have become cheaper. Routing in any network has a great impact on the overall network performance, thus a routing protocol or algorithm for WMN should be carefully designed taking into account the specific characteristics of the network. In addition, in wireless networks, serious unfairness can occur between users if the issue is not addressed in the network protocols or algorithms. In this paper, we are proposing a novel centralized routing algorithm, called Subscriber Aware Fair Routing in WMN (SAFARI, for multiradio WMN that assures fairness, leads to a feasible scheduling, and does not collapse the aggregate network throughput with a strict fairness criterion. We show that our protocol is feasible and practical, and exhaustive simulations show that the performance is improved compared to traditional routing algorithms.

  14. Optimization Model for Headway of a Suburban Bus Route

    Directory of Open Access Journals (Sweden)

    Xiaohong Jiang

    2014-01-01

    Full Text Available Due to relatively low passenger demand, headways of suburban bus route are usually longer than those of urban bus route. Actually it is also difficult to balance the benefits between passengers and operators, subject to the service standards from the government. Hence the headway of a suburban bus route is usually determined on the empirical experience of transport planners. To cope with this problem, this paper proposes an optimization model for designing the headways of suburban bus routes by minimizing the operating and user costs. The user costs take into account both the waiting time cost and the crowding cost. The feasibility and validity of the proposed model are shown by applying it to the Route 206 in Jiangning district, Nanjing city of China. Weightages of passengers’ cost and operating cost are further discussed, considering different passenger flows. It is found that the headway and objective function are affected by the weightages largely.

  15. Observational Study Designs for Comparative Effectiveness Research: An Alternative Approach to Close Evidence Gaps in Head-and-Neck Cancer

    International Nuclear Information System (INIS)

    Goulart, Bernardo H.L.; Ramsey, Scott D.; Parvathaneni, Upendra

    2014-01-01

    Comparative effectiveness research (CER) has emerged as an approach to improve quality of care and patient outcomes while reducing healthcare costs by providing evidence to guide healthcare decisions. Randomized controlled trials (RCTs) have represented the ideal study design to support treatment decisions in head-and-neck (H and N) cancers. In RCTs, formal chance (randomization) determines treatment allocation, which prevents selection bias from distorting the measure of treatment effects. Despite this advantage, only a minority of patients qualify for inclusion in H and N RCTs, which limits the validity of their results to the broader H and N cancer patient population seen in clinical practice. Randomized controlled trials often do not address other knowledge gaps in the management of H and N cancer, including treatment comparisons for rare types of H and N cancers, monitoring of rare or late toxicity events (eg, osteoradionecrosis), or in some instances an RCT is simply not feasible. Observational studies, or studies in which treatment allocation occurs independently of investigators' choice or randomization, may address several of these gaps in knowledge, thereby complementing the role of RCTs. This critical review discusses how observational CER studies complement RCTs in generating the evidence to inform healthcare decisions and improve the quality of care and outcomes of H and N cancer patients. Review topics include a balanced discussion about the strengths and limitations of both RCT and observational CER study designs; a brief description of design and analytic techniques to handle selection bias in observational studies; examples of observational studies that inform current clinical practices and management of H and N cancers; and suggestions for relevant CER questions that could be addressed by an observational study design

  16. Applying visual attention theory to transportation safety research and design: evaluation of alternative automobile rear lighting systems.

    Science.gov (United States)

    McIntyre, Scott E; Gugerty, Leo

    2014-06-01

    This field experiment takes a novel approach in applying methodologies and theories of visual search to the subject of conspicuity in automobile rear lighting. Traditional rear lighting research has not used the visual search paradigm in experimental design. It is our claim that the visual search design uniquely uncovers visual attention processes operating when drivers search the visual field that current designs fail to capture. This experiment is a validation and extension of previous simulator research on this same topic and demonstrates that detection of red automobile brake lamps will be improved if tail lamps are another color (in this test, amber) rather than the currently mandated red. Results indicate that when drivers miss brake lamp onset in low ambient light, RT and error are reduced in detecting the presence and absence of red brake lamps with multiple lead vehicles when tail lamps are not red compared to current rear lighting which mandates red tail lamps. This performance improvement is attributed to efficient visual processing that automatically segregates tail (amber) and brake (red) lamp colors into distractors and targets respectively. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Enhanced Contact Graph Routing (ECGR) MACHETE Simulation Model

    Science.gov (United States)

    Segui, John S.; Jennings, Esther H.; Clare, Loren P.

    2013-01-01

    Contact Graph Routing (CGR) for Delay/Disruption Tolerant Networking (DTN) space-based networks makes use of the predictable nature of node contacts to make real-time routing decisions given unpredictable traffic patterns. The contact graph will have been disseminated to all nodes before the start of route computation. CGR was designed for space-based networking environments where future contact plans are known or are independently computable (e.g., using known orbital dynamics). For each data item (known as a bundle in DTN), a node independently performs route selection by examining possible paths to the destination. Route computation could conceivably run thousands of times a second, so computational load is important. This work refers to the simulation software model of Enhanced Contact Graph Routing (ECGR) for DTN Bundle Protocol in JPL's MACHETE simulation tool. The simulation model was used for performance analysis of CGR and led to several performance enhancements. The simulation model was used to demonstrate the improvements of ECGR over CGR as well as other routing methods in space network scenarios. ECGR moved to using earliest arrival time because it is a global monotonically increasing metric that guarantees the safety properties needed for the solution's correctness since route re-computation occurs at each node to accommodate unpredicted changes (e.g., traffic pattern, link quality). Furthermore, using earliest arrival time enabled the use of the standard Dijkstra algorithm for path selection. The Dijkstra algorithm for path selection has a well-known inexpensive computational cost. These enhancements have been integrated into the open source CGR implementation. The ECGR model is also useful for route metric experimentation and comparisons with other DTN routing protocols particularly when combined with MACHETE's space networking models and Delay Tolerant Link State Routing (DTLSR) model.

  18. Designing augmentative and alternative communication applications: the results of focus groups with speech-language pathologists and parents of children with autism spectrum disorder.

    Science.gov (United States)

    Boster, Jamie B; McCarthy, John W

    2018-05-01

    The purpose of this study was to gain insight from speech-language pathologists (SLPs) and parents of children with autism spectrum disorder (ASD) regarding appealing features of augmentative and alternative communication (AAC) applications. Two separate 1-hour focus groups were conducted with 8 SLPs and 5 parents of children with ASD to identify appealing design features of AAC Apps, their benefits and potential concerns. Participants were shown novel interface designs for communication mode, play mode and incentive systems. Participants responded to poll questions and provided benefits and drawbacks of the features as part of structured discussion. SLPs and parents identified a range of appealing features in communication mode (customization, animation and colour-coding) as well as in play mode (games and videos). SLPs preferred interfaces that supported motor planning and instruction while parents preferred those features such as character assistants that would appeal to their child. Overall SLPs and parents agreed on features for future AAC Apps. SLPs and parents have valuable input in regards to future AAC app design informed by their experiences with children with ASD. Both groups are key stakeholders in the design process and should be included in future design and research endeavors. Implications for Rehabilitation AAC applications for the iPad are often designed based on previous devices without consideration of new features. Ensuring the design of new interfaces are appealing and beneficial for children with ASD can potentially further support their communication. This study demonstrates how key stakeholders in AAC including speech language pathologists and parents can provide information to support the development of future AAC interface designs. Key stakeholders may be an untapped resource in the development of future AAC interfaces for children with ASD.

  19. The future of route survey?

    NARCIS (Netherlands)

    Burger, H.H.; Groot, T. de

    1995-01-01

    Several NATO Navies carry out route survey operations as a peace time operation aimed to improve the MCM efficiency in times of crisis or war. The main result of route survey operations is information about the environmental conditions of an area, and about the mine like contacts present in the

  20. Perception bias in route choice

    NARCIS (Netherlands)

    Vreeswijk, Jacob Dirk; Thomas, Tom; van Berkum, Eric C.; van Arem, Bart

    2014-01-01

    Travel time is probably one of the most studied attributes in route choice. Recently, perception of travel time received more attention as several studies have shown its importance in explaining route choice behavior. In particular, travel time estimates by travelers appear to be biased against non-

  1. Perception bias in route choice

    NARCIS (Netherlands)

    Vreeswijk, Jacob Dirk; Thomas, Tom; van Berkum, Eric C.; van Arem, Bart

    2014-01-01

    Travel time is probably one of the most studied attributes in route choice. Recently, perception of travel time received more attention as several studies have shown its importance in explaining route choice behavior. In particular, travel time estimates by travelers appear to be biased against

  2. A nested recursive logit model for route choice analysis

    DEFF Research Database (Denmark)

    Mai, Tien; Frejinger, Emma; Fosgerau, Mogens

    2015-01-01

    We propose a route choice model that relaxes the independence from irrelevant alternatives property of the logit model by allowing scale parameters to be link specific. Similar to the recursive logit (RL) model proposed by Fosgerau et al. (2013), the choice of path is modeled as a sequence of lin...

  3. Impact of emergency medical services stroke routing protocols on Primary Stroke Center certification in California.

    Science.gov (United States)

    Schuberg, Sam; Song, Sarah; Saver, Jeffrey L; Mack, William J; Cen, Steven Y; Sanossian, Nerses

    2013-12-01

    Organized stroke systems of care include Primary Stroke Center (PSC) certification and preferential emergency medical services (EMS) routing of suspected patients with stroke to designated PSCs. Stroke EMS routing is not nationally governed; in California, routing is determined by county. EMS routing policies might provide an incentive for PSC accreditation. We evaluated the relationship between independent adoption of EMS routing protocols and PSC designation acquisition in California. Dates of PSC certification were obtained through The Joint Commissions Website and confirmatory calls to stroke coordinators. Starting date of county EMS PSC routing policies was obtained from county EMS agencies. We provide descriptive analysis of number of hospitals achieving PSC designation relative to implementation of EMS routing policies for all counties with PSCs. By June 2012, there were 131 California PSCs in 27 counties, and 22 of 58 counties had implemented EMS routing policies. The greatest number of PSCs was in Los Angeles (30) followed by San Diego (11), Orange (9), and Santa Clara (9) counties. Achievement of PSC designation occurred more frequently immediately before and after EMS routing: 51 PSCs (39%) within 1 year; 85 PSCs (65%) within 2 years. The yearly rate of eligible hospital conversion to PSC designation accelerated concurrent with EMS diversion policy adoption from 3.8% before to 16.2% during and decelerated afterward to 7.6%. Implementation of EMS routing policies may be an important factor driving PSC certification. National adoption of stroke routing policies may lead to more PSCs, positively impacting patient care.

  4. An Efficient Method to Design Premature End-of-Life Trajectories: A Hypothetical Alternate Fate for Cassini

    Science.gov (United States)

    Vaquero, Mar; Senent, Juan

    2015-01-01

    What would happen if, hypothetically, the highly successful Cassini mission were to end prematurely due to lack of propellant or sudden subsystem failure? A solid plan to quickly produce a solution for any given scenario, regardless of where the spacecraft is along its reference path, must be in place to safely dispose of the spacecraft and meet all planetary protection requirements. As a contingency plan for this hypothetical situation, a method to design viable high-fidelity terminating trajectories based on a hybrid approach that exploits two-body and three-body flyby transfers combined with a numerical optimization scheme is detailed in this paper.

  5. NOEC and LOEC as merely concessive expedients: two unambiguous alternatives and some criteria to maximize the efficiency of dose-response experimental designs.

    Science.gov (United States)

    Murado, M A; Prieto, M A

    2013-09-01

    NOEC and LOEC (no and lowest observed effect concentrations, respectively) are toxicological concepts derived from analysis of variance (ANOVA), a not very sensitive method that produces ambiguous results and does not provide confidence intervals (CI) of its estimates. For a long time, despite the abundant criticism that such concepts have raised, the field of the ecotoxicology is reticent to abandon them (two possible reasons will be discussed), adducing the difficulty of clear alternatives. However, this work proves that a debugged dose-response (DR) modeling, through explicit algebraic equations, enables two simple options to accurately calculate the CI of substantially lower doses than NOEC. Both ANOVA and DR analyses are affected by the experimental error, response profile, number of observations and experimental design. The study of these effects--analytically complex and experimentally unfeasible--was carried out using systematic simulations with realistic data, including different error levels. Results revealed the weakness of NOEC and LOEC notions, confirmed the feasibility of the proposed alternatives and allowed to discuss the--often violated--conditions that minimize the CI of the parametric estimates from DR assays. In addition, a table was developed providing the experimental design that minimizes the parametric CI for a given set of working conditions. This makes possible to reduce the experimental effort and to avoid the inconclusive results that are frequently obtained from intuitive experimental plans. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. A Multipath Routing Protocol Based on Bloom Filter for Multihop Wireless Networks

    Directory of Open Access Journals (Sweden)

    Junwei Jin

    2016-01-01

    Full Text Available On-demand multipath routing in a wireless ad hoc network is effective in achieving load balancing over the network and in improving the degree of resilience to mobility. In this paper, the salvage capable opportunistic node-disjoint multipath routing (SNMR protocol is proposed, which forms multiple routes for data transmission and supports packet salvaging with minimum overhead. The proposed mechanism constructs a primary path and a node-disjoint backup path together with alternative paths for the intermediate nodes in the primary path. It can be achieved by considering the reverse route back to the source stored in the route cache and the primary path information compressed by a Bloom filter. Our protocol presents higher capability in packet salvaging and lower overhead in forming multiple routes. Simulation results show that SNMR outperforms the compared protocols in terms of packet delivery ratio, normalized routing load, and throughput.

  7. MRS Action Plan Task B report: Analyses of alternative designs and operating approaches for a Monitored Retrievable Storage Facility

    International Nuclear Information System (INIS)

    Woods, W.D.; Jowdy, A.K.; Keehn, C.H.; Gale, R.M.; Smith, R.I.

    1988-12-01

    The Nuclear Waste Policy Amendments Act (NWPAA) instituted a number of changes in the DOE commercial nuclear waste management system. After passage of the Act, the DOE initiated a number of systems studies to reevaluate the role of Monitored Retrievable Storage (MRS) within the federal waste management system. This report summarizes the results of a study to determine the schedules and costs of developing those MRS facilities needed under a number of scenarios, with differing functions allocated to the MRS and/or different spent fuel acceptance schedules. Nine cases were defined for the system study, seven of which included an MRS Facility. The study cases or scenarios evaluated varied relative to the specific functions to be performed at the MRS. The scenarios ranged in magnitude from storage and shipment of bare, intact spent fuel to consolidating the spent fuel into repository emplacement containers prior to storage and shipment. Each scenario required specific modifications to be made to the design developed for the MRS proposal to Congress (the Conceptual Design Report). 41 figs., 326 tabs

  8. Design and validation of realistic breast models for use in multiple alternative forced choice virtual clinical trials.

    Science.gov (United States)

    Elangovan, Premkumar; Mackenzie, Alistair; Dance, David R; Young, Kenneth C; Cooke, Victoria; Wilkinson, Louise; Given-Wilson, Rosalind M; Wallis, Matthew G; Wells, Kevin

    2017-04-07

    A novel method has been developed for generating quasi-realistic voxel phantoms which simulate the compressed breast in mammography and digital breast tomosynthesis (DBT). The models are suitable for use in virtual clinical trials requiring realistic anatomy which use the multiple alternative forced choice (AFC) paradigm and patches from the complete breast image. The breast models are produced by extracting features of breast tissue components from DBT clinical images including skin, adipose and fibro-glandular tissue, blood vessels and Cooper's ligaments. A range of different breast models can then be generated by combining these components. Visual realism was validated using a receiver operating characteristic (ROC) study of patches from simulated images calculated using the breast models and from real patient images. Quantitative analysis was undertaken using fractal dimension and power spectrum analysis. The average areas under the ROC curves for 2D and DBT images were 0.51  ±  0.06 and 0.54  ±  0.09 demonstrating that simulated and real images were statistically indistinguishable by expert breast readers (7 observers); errors represented as one standard error of the mean. The average fractal dimensions (2D, DBT) for real and simulated images were (2.72  ±  0.01, 2.75  ±  0.01) and (2.77  ±  0.03, 2.82  ±  0.04) respectively; errors represented as one standard error of the mean. Excellent agreement was found between power spectrum curves of real and simulated images, with average β values (2D, DBT) of (3.10  ±  0.17, 3.21  ±  0.11) and (3.01  ±  0.32, 3.19  ±  0.07) respectively; errors represented as one standard error of the mean. These results demonstrate that radiological images of these breast models realistically represent the complexity of real breast structures and can be used to simulate patches from mammograms and DBT images that are indistinguishable from

  9. Design and validation of realistic breast models for use in multiple alternative forced choice virtual clinical trials

    Science.gov (United States)

    Elangovan, Premkumar; Mackenzie, Alistair; Dance, David R.; Young, Kenneth C.; Cooke, Victoria; Wilkinson, Louise; Given-Wilson, Rosalind M.; Wallis, Matthew G.; Wells, Kevin

    2017-04-01

    A novel method has been developed for generating quasi-realistic voxel phantoms which simulate the compressed breast in mammography and digital breast tomosynthesis (DBT). The models are suitable for use in virtual clinical trials requiring realistic anatomy which use the multiple alternative forced choice (AFC) paradigm and patches from the complete breast image. The breast models are produced by extracting features of breast tissue components from DBT clinical images including skin, adipose and fibro-glandular tissue, blood vessels and Cooper’s ligaments. A range of different breast models can then be generated by combining these components. Visual realism was validated using a receiver operating characteristic (ROC) study of patches from simulated images calculated using the breast models and from real patient images. Quantitative analysis was undertaken using fractal dimension and power spectrum analysis. The average areas under the ROC curves for 2D and DBT images were 0.51  ±  0.06 and 0.54  ±  0.09 demonstrating that simulated and real images were statistically indistinguishable by expert breast readers (7 observers); errors represented as one standard error of the mean. The average fractal dimensions (2D, DBT) for real and simulated images were (2.72  ±  0.01, 2.75  ±  0.01) and (2.77  ±  0.03, 2.82  ±  0.04) respectively; errors represented as one standard error of the mean. Excellent agreement was found between power spectrum curves of real and simulated images, with average β values (2D, DBT) of (3.10  ±  0.17, 3.21  ±  0.11) and (3.01  ±  0.32, 3.19  ±  0.07) respectively; errors represented as one standard error of the mean. These results demonstrate that radiological images of these breast models realistically represent the complexity of real breast structures and can be used to simulate patches from mammograms and DBT images that are indistinguishable from

  10. Impact of Flooding on Traffic Route Choices

    Directory of Open Access Journals (Sweden)

    Othman M.H.

    2014-01-01

    Full Text Available Traffic route choice using road network modelling can play a key role in preventing and minimizing traffic problems during disasters. Using road network modelling, real road conditions during flooding are simulated in order to produce a response plan for road users to evacuate based on the roads' real risks and situation. Using a Geographical Information System (GIS we can forecast and provide road users with available alternatives when certain access roads or links need to be closed due to catastrophic hazards such as floods. This study focuses on floods as it is the most common form of natural disaster occurring in Malaysia, and due to the fact that the chance and risk of a flood occurring cannot be accurately predicted nor measured. Therefore, as a response to this problem, the outcome of this study is highly useful for the retrieval of information on flooded roads and the impacts on road users. Using GIS's capability to display both spatial and attributive information, we have provided an attractive alternative to conventional methods in order to show available traffic route choices and a transportation network plan.

  11. Design of an accelerated test to determine the attack of the sulphates on concrete structures, and the suggest alternative to design a container

    International Nuclear Information System (INIS)

    Malanca, Rodrigo Sebastian

    2003-01-01

    This work at demonstrating one of the accelerated tests in the frame of the Norm ASTM E-632-82, in order to evaluate the life of service for Reinforced Concrete Structures with High Performance.These will be used as barriers of engineering in containers for Radioactive Wastes.The results of the evaluation are necessary for the probabilistic and deterministic analysis, which are required to obtain licentiate for the emplacement and construction of this type of installations.Since concrete is the principal material used in this type of containers, its properties, in particular, its durability must be evaluated taking into accounts both, intrinsic factors and the extrinsic factors.Within the intrinsic factors we can mention your formulation, including design of armors of steel, production, treated and structural design.As extrinsic factors, weather and environmental, soil characteristic and service operation must be considered.It is important to emphasize that within the criteria used in the conceptual design of these types of repositories, the structures that act of barrier must not alter their insulation properties during all the period of service, which may be several hundreds of years.Although it is not possible to guarantee that repository's performance will not be altered throughout its time of service, the fact to obtain results of accelerated tests and the long term, it will enable us to estimate the durability of such structures, across the support of mathematical suitable models.The different stages which should be taken into account for the development of the evaluation tests, determining the relevant parameters to be considered in them and results obtained so far, are showing in this work

  12. SEARCHING FOR CFC’s AND HCFC’s ALTERNATIVES. Part I: A REFRIGERANT DESIGN STRATEGY USING GROUP CONTRIBUTION METHODS

    Directory of Open Access Journals (Sweden)

    Y KHETIB

    2000-12-01

    Full Text Available It is now well established that the chlorofluorocarbons (CFC’s, the hydrochlorofluorocarbons (HCFC’s and other chlororinated hydrocarbons which are compounds mostly used as refrigerants, are causing more damages than benefits to the environment and particularly to the ozone layer. Therefore one can see how important it is to search for substitutes to these compounds with desirable combination of physical properties to meet the needs of specific applications but, ultimately, with no harms to the environment. In this paper, although the bases of a computer-aided design of refrigerants (CADR method being developed are outlined, the main purpose still remains the demonstration of the great ability and importance of group contribution methods in the development of such techniques, particularly for predicting vapour-liquid equilibria and other thermodynamic properties like the enthalpy or entropy of generated systems, by the use of models like the UNIFAC.

  13. Nanoemulsions containing a synthetic chalcone as an alternative for treating cutaneous leshmaniasis: optimization using a full factorial design.

    Science.gov (United States)

    de Mattos, Cristiane Bastos; Argenta, Débora Fretes; Melchiades, Gabriela de Lima; Cordeiro, Marlon Norberto Sechini; Tonini, Maiko Luis; Moraes, Milene Hoehr; Weber, Tanara Beatriz; Roman, Silvane Souza; Nunes, Ricardo José; Teixeira, Helder Ferreira; Steindel, Mário; Koester, Letícia Scherer

    2015-01-01

    Nanoemulsions are drug delivery systems that may increase the penetration of lipophilic compounds through the skin, enhancing their topical effect. Chalcones are compounds of low water solubility that have been described as promising molecules for the treatment of cutaneous leishmaniasis (CL). In this context, the aim of this work was to optimize the development of a nanoemulsion containing a synthetic chalcone for CL treatment using a 2(2) full factorial design. The formulations were prepared by spontaneous emulsification and the experimental design studied the influence of two independent variables (type of surfactant - soybean lecithin or sorbitan monooleate and type of co-surfactants - polysorbate 20 or polysorbate 80) on the physicochemical characteristics of the nanoemulsions, as well as on the skin permeation/retention of the synthetic chalcone in porcine skin. In order to evaluate the stability of the systems, the antileishmanial assay was performed against Leishmania amazonensis 24 hours and 60 days after the preparation of the nanoemulsions. The formulation composed of soybean lecithin and polysorbate 20 presented suitable physicochemical characteristics (droplet size 171.9 nm; polydispersity index 0.14; zeta potential -39.43 mV; pH 5.16; and viscosity 2.00 cP), drug content (91.09%) and the highest retention in dermis (3.03 µg·g(-1)) - the main response of interest - confirmed by confocal microscopy. This formulation also presented better stability of leishmanicidal activity in vitro against L. amazonensis amastigote forms (half maximal inhibitory concentration value 0.32±0.05 µM), which confirmed the potential of the nanoemulsion soybean lecithin and polysorbate 20 for CL treatment.

  14. An Alternative Approach to "Identification of Unknowns": Designing a Protocol to Verify the Identities of Nitrogen Fixing Bacteria.

    Science.gov (United States)

    Martinez-Vaz, Betsy M; Denny, Roxanne; Young, Nevin D; Sadowsky, Michael J

    2015-12-01

    Microbiology courses often include a laboratory activity on the identification of unknown microbes. This activity consists of providing students with microbial cultures and running biochemical assays to identify the organisms. This approach lacks molecular techniques such as sequencing of genes encoding 16S rRNA, which is currently the method of choice for identification of unknown bacteria. A laboratory activity was developed to teach students how to identify microorganisms using 16S rRNA polymerase chain reaction (PCR) and validate microbial identities using biochemical techniques. We hypothesized that designing an experimental protocol to confirm the identity of a bacterium would improve students' knowledge of microbial identification techniques and the physiological characteristics of bacterial species. Nitrogen-fixing bacteria were isolated from the root nodules of Medicago truncatula and prepared for 16S rRNA PCR analysis. Once DNA sequencing revealed the identity of the organisms, the students designed experimental protocols to verify the identity of rhizobia. An assessment was conducted by analyzing pre- and posttest scores and by grading students' verification protocols and presentations. Posttest scores were higher than pretest scores at or below p = 0.001. Normalized learning gains (G) showed an improvement of students' knowledge of microbial identification methods (LO4, G = 0.46), biochemical properties of nitrogen-fixing bacteria (LO3, G = 0.45), and the events leading to the establishment of nitrogen-fixing symbioses (LO1&2, G = 0.51, G = 0.37). An evaluation of verification protocols also showed significant improvement with a p value of less than 0.001.

  15. Acquisition of business intelligence from human experience in route planning

    Science.gov (United States)

    Bello Orgaz, Gema; Barrero, David F.; R-Moreno, María D.; Camacho, David

    2015-04-01

    The logistic sector raises a number of highly challenging problems. Probably one of the most important ones is the shipping planning, i.e. plan the routes that the shippers have to follow to deliver the goods. In this article, we present an artificial intelligence-based solution that has been designed to help a logistic company to improve its routes planning process. In order to achieve this goal, the solution uses the knowledge acquired by the company drivers to propose optimised routes. Hence, the proposed solution gathers the experience of the drivers, processes it and optimises the delivery process. The solution uses data mining to extract knowledge from the company information systems and prepares it for analysis with a case-based reasoning (CBR) algorithm. The CBR obtains critical business intelligence knowledge from the drivers experience that is needed by the planner. The design of the routes is done by a genetic algorithm that, given the processed information, optimises the routes following several objectives, such as minimise the distance or time. Experimentation shows that the proposed approach is able to find routes that improve, on average, the routes made by the human experts.

  16. North Atlantic IFR Route Planning Chart GEO-TIFF - Aeronautical Information Services Digital Products

    Data.gov (United States)

    Department of Transportation — North Atlantic Route Chart is designed for FAA Controllers to monitor transatlantic flights, this 5-color chart shows oceanic control areas, coastal navigation aids,...

  17. North Atlantic IFR Route Planning Chart PDF File - Aeronautical Information Services Digital Products

    Data.gov (United States)

    Department of Transportation — North Atlantic Route Chart is designed for FAA Controllers to monitor transatlantic flights, this 5-color chart shows oceanic control areas, coastal navigation aids,...

  18. An Alternative Approach to “Identification of Unknowns”: Designing a Protocol to Verify the Identities of Nitrogen Fixing Bacteria

    Directory of Open Access Journals (Sweden)

    Betsy M. Martinez- Vaz

    2015-08-01

    Full Text Available Microbiology courses often include a laboratory activity on the identification of unknown microbes. This activity consists of providing students with microbial cultures and running biochemical assays to identify the organisms. This approach lacks molecular techniques such as sequencing of genes encoding 16S rRNA, which is currently the method of choice for identification of unknown bacteria. A laboratory activity was developed to teach students how to identify microorganisms using 16S rRNA polymerase chain reaction (PCR and validate microbial identities using biochemical techniques. We hypothesized that designing an experimental protocol to confirm the identity of a bacterium would improve students’ knowledge of microbial identification techniques and the physiological characteristics of bacterial species. Nitrogen-fixing bacteria were isolated from the root nodules of Medicago truncatula and prepared for 16S rRNA PCR analysis. Once DNA sequencing revealed the identity of the organisms, the students designed experimental protocols to verify the identity of rhizobia. An assessment was conducted by analyzing pre- and posttest scores and by grading students’ verification protocols and presentations. Posttest scores were higher than pretest scores at or below p = 0.001. Normalized learning gains (G showed an improvement of students’ knowledge of microbial identification methods (LO4, G = 0.46, biochemical properties of nitrogen-fixing bacteria (LO3, G = 0.45, and the events leading to the establishment of nitrogen-fixing symbioses (LO1&2, G = 0.51, G = 0.37. An evaluation of verification protocols also showed significant improvement with a p value of less than 0.001. Editor's Note:The ASM advocates that students must successfully demonstrate the ability to explain and practice safe laboratory techniques. For more information, read the laboratory safety section of the ASM Curriculum Recommendations: Introductory Course in Microbiology and the

  19. Road Routes for Waste Disposal - MDC_RecyclingRoute

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — This CURBSIDE RECYCLING ROUTES BOUNDARIES LAYER IS A polygon feature class created for the Miami-Dade Department of Solid Waste Management (DSWM). It contains the...

  20. Satellite network robust QoS-aware routing

    CERN Document Server

    Long, Fei

    2014-01-01

    Satellite Network Robust QoS-aware Routing presents a novel routing strategy for satellite networks. This strategy is useful for the design of multi-layered satellite networks as it can greatly reduce the number of time slots in one system cycle. The traffic prediction and engineering approaches make the system robust so that the traffic spikes can be handled effectively. The multi-QoS optimization routing algorithm can satisfy various potential user requirements. Clear and sufficient illustrations are also presented in the book. As the chapters cover the above topics independently, readers from different research backgrounds in constellation design, multi-QoS routing, and traffic engineering can benefit from the book.   Fei Long is a senior engineer at Beijing R&D Center of 54th Research Institute of China Electronics Technology Group Corporation.

  1. Assessment of off-design performance of a small-scale combined cooling and power system using an alternative operating strategy for gas turbine

    International Nuclear Information System (INIS)

    Han, Wei; Chen, Qiang; Lin, Ru-mou; Jin, Hong-guang

    2015-01-01

    Highlights: • We develop an off-design model for a CCP system driven by gas turbine. • An alternative operating strategy is proposed to improve the system performance. • Off-design performance of the combined cooling and power system (CCP) is enhanced. • Effects of both the different operating strategy are analyzed and compared. • Performance enhancement mechanism of the proposed operating strategy is presented. - Abstract: A small-scale combined cooling and power (CCP) system usually serves district air conditioning apart from power generation purposes. The typical system consists of a gas turbine and an exhaust gas-fired absorption refrigerator. The surplus heat of the gas turbine is recovered to generate cooling energy. In this way, the CCP system has a high overall efficiency at the design point. However, the CCP system usually runs under off-design conditions because the users’ demand varies frequently. The operating strategy of the gas turbine will affect the thermodynamic performance of itself and the entire CCP system. The operating strategies for gas turbines include the reducing turbine inlet temperature (TIT) and the compressor inlet air throttling (IAT). A CCP system, consisting of an OPRA gas turbine and a double effects absorption refrigerator, is investigated to identify the effects of different operating strategies. The CCP system is simulated based on the partial-load model of gas turbine and absorption refrigerator. The off-design performance of the CCP system is compared under different operating strategies. The results show that the IAT strategy is the better one. At 50% rated power output of the gas turbine, the IAT operating strategy can increase overall system efficiency by 10% compared with the TIT strategy. In general, the IAT operating strategy is suited for other gas turbines. However, the benefits of IAT should be investigated in the future, when different gas turbine is adopted. This study may provide a new operating

  2. An Alternative to Optimize the Indonesian’s Airport Network Design: An Application of Minimum Spanning Tree (MST Technique

    Directory of Open Access Journals (Sweden)

    Luluk Lusiantoro

    2012-09-01

    Full Text Available Using minimum spanning tree technique (MST, this exploratory research was done to optimize the interrelation and hierarchical network design of Indonesian’s airports. This research also identifies the position of the Indonesian’s airports regionally based on the ASEAN Open Sky Policy 2015. The secondary data containing distance between airports (both in Indonesia and in ASEAN, flight frequency, and correlation of Gross Domestic Regional Product (GDRP for each region in Indonesia are used as inputs to form MST networks. The result analysis is done by comparing the MST networks with the existing network in Indonesia. This research found that the existing airport network in Indonesia does not depict the optimal network connecting all airports with the shortest distance and maximizing the correlation of regional economic potential in the country. This research then suggests the optimal networks and identifies the airports and regions as hubs and spokes formed by the networks. Lastly, this research indicates that the Indonesian airports have no strategic position in the ASEAN Open Sky network, but they have an opportunity to get strategic positions if 33 airports in 33 regions in Indonesia are included in the network.

  3. Port Authority of Allegheny County Transit Routes

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Shapefile of Transit Routes - Please refer to each resource for active dates of the route information. Routes change over time,

  4. Alternative Fuels

    Science.gov (United States)

    Alternative fuels include gaseous fuels such as hydrogen, natural gas, and propane; alcohols such as ethanol, methanol, and butanol; vegetable and waste-derived oils; and electricity. Overview of alternative fuels is here.

  5. Predicting Catastrophic BGP Routing Instabilities

    National Research Council Canada - National Science Library

    Nguyen, Lien

    2004-01-01

    .... Currently, this critical function is performed by the Border Gateway Protocol (BGP) version 4 RF01771. Like all routing protocols, BGP is vulnerable to instabilities that reduce its effectiveness...

  6. Comment on the contribution of S.C. Mo, N.A. Hanan and J.E. Matos: 'Comparison of the FRM-II HEU design with an alternative LEU design'

    International Nuclear Information System (INIS)

    Boening, K.

    2004-01-01

    The results of the reference paper, which came to our attention for the first time during this RERTR Meeting, are more or less consistent with neutronic data we have obtained earlier within the FRM-II project (i.e. with own calculations and extrapolations). However, a realistic comparison of the HEU design of the FR.M-II (HEU = highly enriched uranium, 93 % U-235) with an alternative LEU design (LEU = low enriched uranium, 20 % U-235) is only possible on the basis of identical assumptions on the input parameters and has to consider more than neutronic data only. Serious scientists and experts should not confuse the politicians with academic studies touching some aspects of the full story only. The comparison has shown that the performance and reliability of the FRM-II design, which uses HEU fuel, is so advantageous that it can not - not even approximately - be met by an alternative design using LEU fuel. A change of the FRM-II design from HEU to LEU fuel with the results as shown above - i.e. less performance, higher costs, more nuclear waste and higher risk potential, and all of this with a delay of at least 5 years this could never be justified. If a future development of more advanced fuels should allow us to achieve our scientific goals at the conditions as identified above also with uranium of reduced enrichment - there would be no objection to a corresponding later conversion. Activities to realize a new neutron source in Germany go back to the late 70's with the project of a new middle flux beam reactor (MSR), which was abandoned shortly later in favour of an ambitious new spallation neutron source (SNQ). After this project also having been terminated around 1985 because of too high costs and technological risks, the hopes of the German community of neutron scientists focussed on the FRM-II. If non-technical pressure would damage this project this would equally provide irreversible damage to the large and still prospering field of neutron research in Germany

  7. Energy Conservation Alternatives Study (ECAS): Conceptual Design and Implementation Assessment of a Utility Steam Plant with Conventional Furnace and Wet Lime Stack Gas Scrubbers

    Science.gov (United States)

    Brown, Dale H.

    1976-01-01

    A study was performed to estimate the technical/economic characteristics of a steam power plant (3500 pounds per square inch gauge, 1000 degrees Fahrenheit / 1000 degrees Fahrenheit) with a coal-burning radiant furnace and a wet lime stack gas scrubber to control sulfur emissions. Particulate emissions were controlled by an electrostatic precipitator operating at 300 degrees Fahrenheit. The stack gas from the scrubber was reheated from 125 degrees Fahrenheit to 250 degrees Fahrenheit as a base case, and from 125 degrees Fahrenheit to 175 degrees Fahrenheit as an alternate case. The study was performed on a basis consistent with the General Electric ECAS Phase II evaluation of advanced energy conversion systems for electric utility baseload applications using coal or coal-derived fuels. A conceptual design of the power plant was developed, including the on-site calcination of limestone to lime and the provision of sludge ponds to store the products of flue gas scrubbing. From this design, estimates were derived for power plant efficiency, capital cost, environmental intrusion characteristics, natural resource requirements, and cost of electricity at an assumed capacity factor of 65 percent. An implementation assessment was performed where factors affecting applicability of the conceptual design power plant in electric utility generation systems were appraised. At 250 degrees Fahrenheit and 175 degrees Fahrenheit stack gas temperatures respectively, the plants showed a cost of electricity of 39.8 and 37.0 mills per kilowatt-hours and overall plant efficiencies of 32 percent and 34 percent.

  8. New TPG bus route 28

    CERN Multimedia

    2003-01-01

    Geneva's Public Transport services (TPG) have recently inaugurated a new bus line 28, connecting the La Tour Hospital in Meyrin to the international organisations in Geneva, via the airport. All signs associated with this route will be yellow in colour. Timetables and route details can be found at http://www.tpg.ch. Relations with the Host States Service http://www.cern.ch/relations/ Tel. 72848

  9. Many routes lead to Rome: potential causes for the multi-route migration system of Red Knots, Calidris canutus Islandica.

    Science.gov (United States)

    Bauer, Silke; Ens, Bruno J; Klaassen, Marcel

    2010-06-01

    Migrants, such as birds or representatives of other taxa, usually make use of several stopover sites to cover the distance between their site of origin and destination. Potentially, multiple routes exist, but often little is known about the causes and consequences of alternative migration routes. Apart from their geographical distribution, the suitability of potential sites might play an important role in the animals' decisions for a particular itinerary. We used an optimal-migration model to test three nonmutually exclusive hypotheses leading to variations in the spring migration routes of a subspecies of Red Knot, Calidris canutus islandica, which migrates from wintering grounds in Western Europe to breeding grounds in Greenland and the Canadian Arctic: the breeding location hypothesis, the energy budget hypothesis, and the predation risk hypothesis. Varying only breeding location, the model predicted that birds breeding in the Canadian Arctic and on West Greenland stop over on Iceland, whereas birds breeding in East and Northeast Greenland migrate via northern Norway, a prediction that is supported by empirical findings. Energy budgets on stopover sites had a strong influence on the choice of route and staging times. Varying foraging-intensity and mass-dependent predation risk prompted the birds to use less risky sites, if possible. The effect of simultaneous changes in the energy budget and predation risk strongly depended on the site where these occurred. Our findings provide potential explanations for the observations that C. canutus islandica uses a diverse array of migration routes. Scrutinizing the three alternative driving forces for the choice of migratory routes awaits further, specific data collection in rapidly developing fields of research (e.g., predation risk assessment, GPS tracking). Generally, the type of modeling presented here may not only highlight alternative explanations, but also direct follow-up empirical research.

  10. Planning Routes Across Economic Terrains: Maximizing Utility, Following Heuristics

    Science.gov (United States)

    Zhang, Hang; Maddula, Soumya V.; Maloney, Laurence T.

    2010-01-01

    We designed an economic task to investigate human planning of routes in landscapes where travel in different kinds of terrain incurs different costs. Participants moved their finger across a touch screen from a starting point to a destination. The screen was divided into distinct kinds of terrain and travel within each kind of terrain imposed a cost proportional to distance traveled. We varied costs and spatial configurations of terrains and participants received fixed bonuses minus the total cost of the routes they chose. We first compared performance to a model maximizing gain. All but one of 12 participants failed to adopt least-cost routes and their failure to do so reduced their winnings by about 30% (median value). We tested in detail whether participants’ choices of routes satisfied three necessary conditions (heuristics) for a route to maximize gain. We report failures of one heuristic for 7 out of 12 participants. Last of all, we modeled human performance with the assumption that participants assign subjective utilities to costs and maximize utility. For 7 out 12 participants, the fitted utility function was an accelerating power function of actual cost and for the remaining 5, a decelerating power function. We discuss connections between utility aggregation in route planning and decision under risk. Our task could be adapted to investigate human strategy and optimality of route planning in full-scale landscapes. PMID:21833269

  11. Expanding the applicability of random regret minimization for route choice analysis

    DEFF Research Database (Denmark)

    Prato, Carlo Giacomo

    2014-01-01

    The discrete choice paradigm of random regret minimization (RRM) has been recently proposed in several choice contexts. In the route choice context, the paradigm has been used to model the choice among three routes and to formulate regret-based stochastic user equilibrium. However, in the same...... context the RRM literature has not confronted three major challenges: (i) accounting for similarities across alternative routes, (ii) analyzing choice set composition effects on choice probabilities, and (iii) comparing RRMbased models with advanced RUM-based models. This paper looks into RRM-based route...... choice models from these three perspectives by (i) proposing utility-based and regret-based correction terms to account for similarities across alternatives, (ii) analyzing the variation of choice set probabilities with the choice set composition, and (iii) comparing RRM-based route choice models with C...

  12. Simulations of the Impact of Controlled Mobility for Routing Protocols

    Directory of Open Access Journals (Sweden)

    Loscrí Valeria

    2010-01-01

    Full Text Available This paper addresses mobility control routing in wireless networks. Given a data flow request between a source-destination pair, the problem is to move nodes towards the best placement, such that the performance of the network is improved. Our purpose is to find the best nodes selection depending on the minimization of the maximum distance that nodes have to travel to reach their final position. We propose a routing protocol, the Routing Protocol based on Controlled Mobility (RPCM, where the chosen nodes' path minimizes the total travelled distance to reach desirable position. Specifically, controlled mobility is intended as a new design dimension network allowing to drive nodes to specific best position in order to achieve some common objectives. The main aim of this paper is to show by simulation the effectiveness of controlled mobility when it is used as a new design dimension in wireless networks. Extensive simulations are conducted to evaluate the proposed routing algorithm. Results show how our protocol outperforms a well-known routing protocol, the Ad hoc On Demand Distance Vector routing (AODV, in terms of throughput, average end-to-end data packet delay and energy spent to send a packet unit.

  13. Assessing Evacuation Route Against Mount Merapi Hazard By Using Least Cost Path Method in Mriyan-Boyolali, Indonesia

    Science.gov (United States)

    Putri, L. K. R.; Maryono, M.

    2018-02-01

    This research aims to analyze the Least-Cost Path, an ArcGIS raster analysis, as a tool to find the evacuation route. The evacuation route of mount Merapi Eruption in Mriyan- Musuk of Boyolali regency in the scenario of sister village with Kiringan Village was selected as case study. There are 4 steps of analysis in this method such as; cost surface, cost distance cost backlink and cost path. This study analysis found 3 alternative routes which estimates 25-30 minute. These alternatives evacuation route are useful in distributing the flow of people when the eruption occurs.

  14. Bicyclists’ preferences for route characteristics and crowding in Copenhagen

    DEFF Research Database (Denmark)

    Vedel, Suzanne Elizabeth; Jacobsen, Jette Bredahl; Skov-Petersen, Hans

    2017-01-01

    Cycling as a mode of transportation is increasingly being advocated due to the many positive effects it has on people's health, the environment and to counteract increasing congestion on the transportation infrastructure. There is a long tradition of using cycling as a mode of transportation among....... The investigated attributes are cycle track, crowding, stops, environment/road type, green surroundings, and travel distance which is used as a payment vehicle to gain more desirable route characteristics. On average people state that they are willing to cycle 1.84 km longer if the route has a designated cycle...... track, and 0.8 km more if there are green surroundings too. Stops and crowding, based on number of cyclists on the route, have significant negative impacts on people's utility of a given route. People were willing to cycle one kilometre longer to avoid high levels of crowding and approximately 1.3 km...

  15. Intelligent deflection routing in buffer-less networks.

    Science.gov (United States)

    Haeri, Soroush; Trajković, Ljiljana

    2015-02-01

    Deflection routing is employed to ameliorate packet loss caused by contention in buffer-less architectures such as optical burst-switched networks. The main goal of deflection routing is to successfully deflect a packet based only on a limited knowledge that network nodes possess about their environment. In this paper, we present a framework that introduces intelligence to deflection routing (iDef). iDef decouples the design of the signaling infrastructure from the underlying learning algorithm. It consists of a signaling and a decision-making module. Signaling module implements a feedback management protocol while the decision-making module implements a reinforcement learning algorithm. We also propose several learning-based deflection routing protocols, implement them in iDef using the ns-3 network simulator, and compare their performance.

  16. Delay Tolerance in Underwater Wireless Communications: A Routing Perspective

    Directory of Open Access Journals (Sweden)

    Safdar Hussain Bouk

    2016-01-01

    Full Text Available Similar to terrestrial networks, underwater wireless networks (UWNs also aid several critical tasks including coastal surveillance, underwater pollution detection, and other maritime applications. Currently, once underwater sensor nodes are deployed at different levels of the sea, it is nearly impossible or very expensive to reconfigure the hardware, for example, battery. Taking this issue into account, considerable amount of research has been carried out to ensure minimum energy costs and reliable communication between underwater nodes and base stations. As a result, several different network protocols were proposed for UWN, including MAC, PHY, transport, and routing. Recently, a new paradigm was introduced claiming that the intermittent nature of acoustic channel and signal resulted in designing delay tolerant routing schemes for the UWN, known as an underwater delay tolerant network. In this paper, we provide a comprehensive survey of underwater routing protocols with emphasis on the limitations, challenges, and future open issues in the context of delay tolerant network routing.

  17. Air Cargo Transportation Route Choice Analysis

    Science.gov (United States)

    Obashi, Hiroshi; Kim, Tae-Seung; Oum, Tae Hoon

    2003-01-01

    Using a unique feature of air cargo transshipment data in the Northeast Asian region, this paper identifies the critical factors that determine the transshipment route choice. Taking advantage of the variations in the transport characteristics in each origin-destination airports pair, the paper uses a discrete choice model to describe the transshipping route choice decision made by an agent (i.e., freight forwarder, consolidator, and large shipper). The analysis incorporates two major factors, monetary cost (such as line-haul cost and landing fee) and time cost (i.e., aircraft turnaround time, including loading and unloading time, custom clearance time, and expected scheduled delay), along with other controls. The estimation method considers the presence of unobserved attributes, and corrects for resulting endogeneity by use of appropriate instrumental variables. Estimation results find that transshipment volumes are more sensitive to time cost, and that the reduction in aircraft turnaround time by 1 hour would be worth the increase in airport charges by more than $1000. Simulation exercises measures the impacts of alternative policy scenarios for a Korean airport, which has recently declared their intention to be a future regional hub in the Northeast Asian region. The results suggest that reducing aircraft turnaround time at the airport be an effective strategy, rather than subsidizing to reduce airport charges.

  18. Robustness of airline alliance route networks

    Science.gov (United States)

    Lordan, Oriol; Sallan, Jose M.; Simo, Pep; Gonzalez-Prieto, David

    2015-05-01

    The aim of this study is to analyze the robustness of the three major airline alliances' (i.e., Star Alliance, oneworld and SkyTeam) route networks. Firstly, the normalization of a multi-scale measure of vulnerability is proposed in order to perform the analysis in networks with different sizes, i.e., number of nodes. An alternative node selection criterion is also proposed in order to study robustness and vulnerability of such complex networks, based on network efficiency. And lastly, a new procedure - the inverted adaptive strategy - is presented to sort the nodes in order to anticipate network breakdown. Finally, the robustness of the three alliance networks are analyzed with (1) a normalized multi-scale measure of vulnerability, (2) an adaptive strategy based on four different criteria and (3) an inverted adaptive strategy based on the efficiency criterion. The results show that Star Alliance has the most resilient route network, followed by SkyTeam and then oneworld. It was also shown that the inverted adaptive strategy based on the efficiency criterion - inverted efficiency - shows a great success in quickly breaking networks similar to that found with betweenness criterion but with even better results.

  19. Vehicle Routing With User Generated Trajectory Data

    DEFF Research Database (Denmark)

    Ceikute, Vaida; Jensen, Christian S.

    Rapidly increasing volumes of GPS data collected from vehicles provide new and increasingly comprehensive insight into the routes that drivers prefer. While routing services generally compute shortest or fastest routes, recent studies suggest that local drivers often prefer routes that are neithe...

  20. Energy-Efficient Routing in GMPLS Network

    DEFF Research Database (Denmark)

    Wang, Jiayuan; Fagertun, Anna Manolova; Ruepp, Sarah Renée

    2011-01-01

    In this paper, a GMPLS controlled core network model that takes energy efficiency into account is built using OPNET MODELER. By extending the standard GMPLS routing protocol -- OSPF-TE, we are able to spread desired energy related information over the local area, and subsequently use RSVP......-TE for connection setup. The OSPF designing process of the simulation model is given in details, including necessary simplifications to enable a fast implementation while keeping the key characteristics of the GMPLS protocol behaviors. The efficiency of the proposed extensions are analyzed, and improved energy...

  1. Addressing holistic healthcare needs of oncology patients: Implementation and evaluation of a complementary and alternative medicine (CAM) course within an elective module designed for healthcare professionals.

    Science.gov (United States)

    Klafke, Nadja; Homberg, Angelika; Glassen, Katharina; Mahler, Cornelia

    2016-12-01

    Patients, and especially oncology patients, increasingly demand information and application of complementary therapies to supplement their conventional medical treatment and follow-up care. Due to the widespread interest in holistic treatment opportunities in oncology populations, healthcare professionals need to be prepared in differentiating evidence-based methods of the complementary and alternative medicine (CAM) spectrum and how to consult with patients about it. This paper reports on the implementation and evaluation of a newly designed module "Complementary and Alternative Medicine in oncological healthcare" in the bachelor degree program Interprofessional Health Care (B.Sc.). The study applied a developed evaluation questionnaire to capture students' perspectives on the CAM contents. This assessment instrument was administered pre and post the CAM teaching unit. Interprofessional medical education, University Hospital Heidelberg, Germany. The integration of the CAM elective module was possible and was met by positive response. Students' interest was reflected in an increase of their self-reported knowledge gain and positive CAM attitude. Comparison of pre and post evaluation data demonstrate that, particularly, students' expectations on developing their own opinion about CAM, and getting an overview of the evidence-base of different CAM methods have been met. Evaluation results indicate that the module content was in line with the students' expectations and may have positively impacted on their general CAM attitude. The results support us in continuing to offer this CAM course within the elective module to prepare today's healthcare professionals for patient-oriented healthcare delivery. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Immunological properties of gene vaccines delivered by different routes

    Directory of Open Access Journals (Sweden)

    Oliveira S.C.

    1999-01-01

    Full Text Available Gene vaccines represent a new and promising approach to control infectious diseases, inducing a protective immune response in the appropriate host. Several routes and methods of genetic immunization have been shown to induce antibody production as well as T helper (Th cell and cytotoxic T lymphocyte activation. However, few studies have compared the nature of the immune responses generated by different gene vaccination delivery systems. In the present study we reviewed some aspects of immunity induced by gene immunization and compared the immune responses produced by intramuscular (im DNA injection to gene gun-mediated DNA transfer into the skin of BALB/c mice. Using a reporter gene coding for ß-galactosidase, we have demonstrated that im injection raised a predominantly Th1 response with mostly IgG2a anti-ßgal produced, while gene gun immunization induced a mixed Th1/Th2 profile with a balanced production of IgG2a and IgG1 subclasses. Distinct types of immune responses were generated by different methods of gene delivery. These findings have important implications for genetic vaccine design. Firstly, a combination between these two systems may create optimal conditions for the induction of a broad-based immune response. Alternatively, a particular gene vaccine delivery method might be used according to the immune response required for host protection. Here, we describe the characteristics of the immune response induced by gene vaccination and the properties of DNA involved in this process.

  3. Route simulations, compass mechanisms and long-distance migration flights in birds.

    Science.gov (United States)

    Åkesson, Susanne; Bianco, Giuseppe

    2017-07-01

    Bird migration has fascinated humans for centuries and routes crossing the globe are now starting to be revealed by advanced tracking technology. A central question is what compass mechanism, celestial or geomagnetic, is activated during these long flights. Different approaches based on the geometry of flight routes across the globe and route simulations based on predictions from compass mechanisms with or without including the effect of winds have been used to try to answer this question with varying results. A major focus has been use of orthodromic (great circle) and loxodromic (rhumbline) routes using celestial information, while geomagnetic information has been proposed for both a magnetic loxodromic route and a magnetoclinic route. Here, we review previous results and evaluate if one or several alternative compass mechanisms can explain migration routes in birds. We found that most cases could be explained by magnetoclinic routes (up to 73% of the cases), while the sun compas s could explain only 50%. Both magnetic and geographic loxodromes could explain <25% of the routes. The magnetoclinic route functioned across latitudes (1°S-74°N), while the sun compass only worked in the high Arctic (61-69°N). We discuss the results with respect to orientation challenges and availability of orientation cues.

  4. Deterministic Greedy Routing with Guaranteed Delivery in 3D Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Su Xia

    2014-05-01

    Full Text Available With both computational complexity and storage space bounded by a small constant, greedy routing is recognized as an appealing approach to support scalable routing in wireless sensor networks. However, significant challenges have been encountered in extending greedy routing from 2D to 3D space. In this research, we develop decentralized solutions to achieve greedy routing in 3D sensor networks. Our proposed approach is based on a unit tetrahedron cell (UTC mesh structure. We propose a distributed algorithm to realize volumetric harmonic mapping (VHM of the UTC mesh under spherical boundary condition. It is a one-to-one map that yields virtual coordinates for each node in the network without or with one internal hole. Since a boundary has been mapped to a sphere, node-based greedy routing is always successful thereon. At the same time, we exploit the UTC mesh to develop a face-based greedy routing algorithm and prove its success at internal nodes. To deliver a data packet to its destination, face-based and node-based greedy routing algorithms are employed alternately at internal and boundary UTCs, respectively. For networks with multiple internal holes, a segmentation and tunnel-based routing strategy is proposed on top of VHM to support global end-to-end routing. As far as we know, this is the first work that realizes truly deterministic routing with constant-bounded storage and computation in general 3D wireless sensor networks.

  5. New conceptual design of portable bamboo bridge for emergency purposes

    Science.gov (United States)

    Musthaffa, A. A.; Nor, N. M.; Yusof, M. A.; Yuhazri, M. Y.

    2018-02-01

    Portable bridges serve as routes for troops during the military operations and the disaster relief operation. Nowadays, bamboo has been regarded as one of the alternative construction materials for building and bridge structures. This paper presents the conceptual design of the portable bridge. Several types of portable bridges and bamboo bridges are reviewed in the current work. The characteristics, capability and method of construction of each bridge are discussed. Finally, the conceptual of the portable bamboo bridge for emergency purposes is presented. The idea of producing portable bridge is proposed in the current work as it is crucial for providing route for communities affected by natural disasters.

  6. Design and Testing of Digital Microfluidic Biochips

    CERN Document Server

    Zhao, Yang

    2013-01-01

    This book provides a comprehensive methodology for automated design, test and diagnosis, and use of robust, low-cost, and manufacturable digital microfluidic systems. It focuses on the development of a comprehensive CAD optimization framework for digital microfluidic biochips that unifies different design problems. With the increase in system complexity and integration levels, biochip designers can utilize the design methods described in this book to evaluate different design alternatives, and carry out design-space exploration to obtain the best design point. Describes practical design automation tools that address different design problems (e.g., synthesis, droplet routing, control-pin mapping, testing and diagnosis, and error recovery) in a unified manner; Applies test pattern generation and error-recovery techniques for digital microfluidics-based biochips; Uses real bioassays as evaluation examples, e.g., multiplexed in vitro human physiological fluids diagnostics, PCR, protein crystallization.  

  7. Modeling Stochastic Route Choice Behaviors with Equivalent Impedance

    Directory of Open Access Journals (Sweden)

    Jun Li

    2015-01-01

    Full Text Available A Logit-based route choice model is proposed to address the overlapping and scaling problems in the traditional multinomial Logit model. The nonoverlapping links are defined as a subnetwork, and its equivalent impedance is explicitly calculated in order to simply network analyzing. The overlapping links are repeatedly merged into subnetworks with Logit-based equivalent travel costs. The choice set at each intersection comprises only the virtual equivalent route without overlapping. In order to capture heterogeneity in perception errors of different sizes of networks, different scale parameters are assigned to subnetworks and they are linked to the topological relationships to avoid estimation burden. The proposed model provides an alternative method to model the stochastic route choice behaviors without the overlapping and scaling problems, and it still maintains the simple and closed-form expression from the MNL model. A link-based loading algorithm based on Dial’s algorithm is proposed to obviate route enumeration and it is suitable to be applied on large-scale networks. Finally a comparison between the proposed model and other route choice models is given by numerical examples.

  8. Multipath Load Balancing Routing for Internet of Things

    Directory of Open Access Journals (Sweden)

    Chinyang Henry Tseng

    2016-01-01

    Full Text Available In the next-generation technology, Internet of Things (IoT, billions of smart objects will communicate with one another to make human lives more convenient. IoT is based on wireless sensor network (WSN, and Zigbee is one of the most popular WSN protocols. A mature IoT environment involves heavy WSN data transmission causing bottleneck problems. However, Zigbee’s AODV routing stack does not have load balance mechanism to handle bursty traffic. Therefore, we develop Multipath Load Balancing (MLB Routing to substitute Zigbee’s AODV routing. Our proposed MLB consists of two main designs: LAYER_DESIGN and LOAD_BALANCE. LAYER_DESIGN assigns nodes into different layers based on node distance to IoT gateway. Nodes can have multiple next-hops delivering IoT data. All neighboring layer nodes exchange flow information containing current load, used by LOAD_BALANCE to estimate future load of next-hops. With MLB, nodes can choose the neighbors with the least load as the next-hops and thus can achieve load balance and avoid bottlenecks. Compared with Zigbee’s AODV and multipath version AODV (AOMDV, experiment results demonstrate that MLB achieves better load balance, lower packet loss rate, and better routing connectivity ratio in both grid and random uniform topologies. MLB provides a more convincing routing solution for IoT applications.

  9. Estimating Influenza Vaccine Effectiveness With the Test-Negative Design Using Alternative Control Groups: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Feng, Shuo; Cowling, Benjamin J; Kelly, Heath; Sullivan, Sheena G

    2018-02-01

    One important assumption in case-control studies is that control selection should be independent of exposure. Nevertheless, it has been hypothesized that virus interference might lead to a correlation between receipt of influenza vaccination and increased risk of infection with other respiratory viruses. We investigated whether such a phenomenon might affect a study design commonly used to estimate influenza vaccine effectiveness (VE). We searched publications in MEDLINE, PubMed, and Web of Science. We identified 12 studies using the test-negative design (2011-2017) that reported VE estimates separately derived by 3 alternative control groups: 1) all patients testing negative for influenza (FLU), VEFLU-; 2) patients who tested positive for other/another respiratory virus (ORV), VEORV+; and 3) patients who tested negative for all viruses in the panel (PAN), VEPAN-. These included VE estimates from 7 countries for all age groups from 2003/2004 to 2013/2014. We observed no difference in vaccination coverage between the ORV-positive and PAN-negative control groups. A total of 63 VEFLU- estimates, 62 VEORV+ estimates, and 33 VEPAN- estimates were extracted. Pooled estimates of the difference in VE (ΔVE) were very similar between groups. In meta-regression, no association was found between the selection of control group and VE estimates. In conclusion, we did not find any differences in VE estimates based on the choice of control group. © The Author(s) 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. Comparative assessment of spent nuclear fuel transportation routes using risk factors and a geographic information system

    International Nuclear Information System (INIS)

    Toth, D.M.

    1996-01-01

    The assessment of potential alternative routes was simplified through the use of six comparative risk factors evaluated using detailed, route-specific data. The route and environmental attributes varied strongly with location and were developed from national, state, and local sources. The six comparative factors were risk measures of incident-free transportation radiation exposure, radiological accident population exposure, nonradiological accidents, contamination of environmental sensitive areas, environmental justice for minority populations, and environmental justice for low-income populations. An assessment of four real North-Central Florida routes provided a sample implementation of the analysis tools and risk factors. The assessment routes, consisting of common beginning and end locations, included an interstate highway, a rural highway, a mostly urban highway, and a combination interstate highway with rural bypass. This route comparative assessment study predicted that the interstate highway, despite a higher population density, greater traffic volume, and greater number of vehicular fatality accidents, would present the lowest cumulative risk. On the contrary, the rural highway route, characterized as having the lowest population density, minimal vehicle traffic volume, and the lowest percentages of minority and low-income populations, displayed the highest cumulative risk measure. Factors contributing to the high risk for the rural highway route included greater route length, higher vehicular fatality accident rates per vehicle mile traveled, and the close proximity to environmentally sensitive areas. This route comparative assessment study predicted that the interstate highway, despite a higher population density, greater traffic volume, and greater number of vehicular fatality accidents, would present the lowest cumulative risk. On the contrary, the rural highway route, characterized as having the lowest population density, minimal vehicle traffic volume

  11. Junos Enterprise Routing A Practical Guide to Junos Routing and Certification

    CERN Document Server

    Southwick, Peter; Reynolds, Harry

    2011-01-01

    Considered the go-to study guide for Juniper Networks enterprise routing certification exams, this book offers you unparalleled coverage of all the services available to Junos administrators-including the most recent set of flow-based security services and design guidelines that incorporate services and features of the MX, SRX, and EX network devices. Its emphasis on practical solutions also makes this book an ideal on-the-job reference for design, maintenance, and troubleshooting issues in the enterprise. Simply put, this updated edition is the most comprehensive and authoritative resource

  12. Multipath Routing in Wireless Sensor Networks: Survey and Research Challenges

    Science.gov (United States)

    Radi, Marjan; Dezfouli, Behnam; Bakar, Kamalrulnizam Abu; Lee, Malrey

    2012-01-01

    A wireless sensor network is a large collection of sensor nodes with limited power supply and constrained computational capability. Due to the restricted communication range and high density of sensor nodes, packet forwarding in sensor networks is usually performed through multi-hop data transmission. Therefore, routing in wireless sensor networks has been considered an important field of research over the past decade. Nowadays, multipath routing approach is widely used in wireless sensor networks to improve network performance through efficient utilization of available network resources. Accordingly, the main aim of this survey is to present the concept of the multipath routing approach and its fundamental challenges, as well as the basic motivations for utilizing this technique in wireless sensor networks. In addition, we present a comprehensive taxonomy on the existing multipath routing protocols, which are especially designed for wireless sensor networks. We highlight the primary motivation behind the development of each protocol category and explain the operation of different protocols in detail, with emphasis on their advantages and disadvantages. Furthermore, this paper compares and summarizes the state-of-the-art multipath routing techniques from the network application point of view. Finally, we identify open issues for further research in the development of multipath routing protocols for wireless sensor networks. PMID:22368490

  13. A network coding based routing protocol for underwater sensor networks.

    Science.gov (United States)

    Wu, Huayang; Chen, Min; Guan, Xin

    2012-01-01

    Due to the particularities of the underwater environment, some negative factors will seriously interfere with data transmission rates, reliability of data communication, communication range, and network throughput and energy consumption of underwater sensor networks (UWSNs). Thus, full consideration of node energy savings, while maintaining a quick, correct and effective data transmission, extending the network life cycle are essential when routing protocols for underwater sensor networks are studied. In this paper, we have proposed a novel routing algorithm for UWSNs. To increase energy consumption efficiency and extend network lifetime, we propose a time-slot based routing algorithm (TSR).We designed a probability balanced mechanism and applied it to TSR. The theory of network coding is introduced to TSBR to meet the requirement of further reducing node energy consumption and extending network lifetime. Hence, time-slot based balanced network coding (TSBNC) comes into being. We evaluated the proposed time-slot based balancing routing algorithm and compared it with other classical underwater routing protocols. The simulation results show that the proposed protocol can reduce the probability of node conflicts, shorten the process of routing construction, balance energy consumption of each node and effectively prolong the network lifetime.

  14. Multipath routing in wireless sensor networks: survey and research challenges.

    Science.gov (United States)

    Radi, Marjan; Dezfouli, Behnam; Abu Bakar, Kamalrulnizam; Lee, Malrey

    2012-01-01

    A wireless sensor network is a large collection of sensor nodes with limited power supply and constrained computational capability. Due to the restricted communication range and high density of sensor nodes, packet forwarding in sensor networks is usually performed through multi-hop data transmission. Therefore, routing in wireless sensor networks has been considered an important field of research over the past decade. Nowadays, multipath routing approach is widely used in wireless sensor networks to improve network performance through efficient utilization of available network resources. Accordingly, the main aim of this survey is to present the concept of the multipath routing approach and its fundamental challenges, as well as the basic motivations for utilizing this technique in wireless sensor networks. In addition, we present a comprehensive taxonomy on the existing multipath routing protocols, which are especially designed for wireless sensor networks. We highlight the primary motivation behind the development of each protocol category and explain the operation of different protocols in detail, with emphasis on their advantages and disadvantages. Furthermore, this paper compares and summarizes the state-of-the-art multipath routing techniques from the network application point of view. Finally, we identify open issues for further research in the development of multipath routing protocols for wireless sensor networks.

  15. Dynamic Weather Routes Architecture Overview

    Science.gov (United States)

    Eslami, Hassan; Eshow, Michelle

    2014-01-01

    Dynamic Weather Routes Architecture Overview, presents the high level software architecture of DWR, based on the CTAS software framework and the Direct-To automation tool. The document also covers external and internal data flows, required dataset, changes to the Direct-To software for DWR, collection of software statistics, and the code structure.

  16. Overview: Routes to Open Access

    OpenAIRE

    Tullney, Marco; van Wezenbeek, Wilma

    2017-01-01

    Slides of an overview presentation given at a CESAER workshop on Open Access, February 2nd, 2017, in Brussels Cover major routes to more open access as discussed in the Task Force Open Science of CESAER: (national) open access strategies open access mandates open access incentives open access awareness open access publishing open access infrastructure

  17. Roots/Routes: Part I

    Science.gov (United States)

    Swanson, Dalene M.

    2009-01-01

    This narrative and poetic rendering acts as an articulation of a journey of many routes. It is a storying of critical research issues and events as performances of lived experience. It is a metissage of hybrid, but interrelated, themes that find cohesion through fragmentation and coalescence, severance, and regrowth. These themes are invoked by…

  18. Roots/Routes: Part II

    Science.gov (United States)

    Swanson, Dalene M.

    2009-01-01

    This narrative acts as an articulation of a journey of many routes. Following Part I of the same research journey of rootedness/routedness, it debates the nature of transformation and transcendence beyond personal and political paradoxes informed by neoliberalism and related repressive globalizing discourses. Through a more personal, descriptive,…

  19. Population estimation techniques for routing analysis

    International Nuclear Information System (INIS)

    Sathisan, S.K.; Chagari, A.K.

    1994-01-01

    A number of on-site and off-site factors affect the potential siting of a radioactive materials repository at Yucca Mountain, Nevada. Transportation related issues such route selection and design are among them. These involve evaluation of potential risks and impacts, including those related to population. Population characteristics (total population and density) are critical factors in the risk assessment, emergency preparedness and response planning, and ultimately in route designation. This paper presents an application of Geographic Information System (GIS) technology to facilitate such analyses. Specifically, techniques to estimate critical population information are presented. A case study using the highway network in Nevada is used to illustrate the analyses. TIGER coverages are used as the basis for population information at a block level. The data are then synthesized at tract, county and state levels of aggregation. Of particular interest are population estimates for various corridor widths along transport corridors -- ranging from 0.5 miles to 20 miles in this paper. A sensitivity analysis based on the level of data aggregation is also presented. The results of these analysis indicate that specific characteristics of the area and its population could be used as indicators to aggregate data appropriately for the analysis

  20. CulRoute: Gamified WebGIS3D platform for selection of touristic routes

    Directory of Open Access Journals (Sweden)

    E.P.L. Baptista

    2015-11-01

    Full Text Available The importance of tourist information disclosure on digital platforms is, nowadays, reinforced by public entities such as Turismo de Portugal and Turismo do Algarve. The incorporation of strategies to encourage greater interest and involvement of the users are likely to contribute to a more effective dissemination of tourist destinations and their historical and cultural heritage. This paper presents the concepts, strategies and technologies in the design and implementation of the gamified WebGIS3D platform named CulRoute. This platform enables the users to visualize and navigate the three-dimensional virtual models of monuments and to explore the 'treasures' of each monument in a gaming environment, as well as to test their knowledge by answering optional quizzes. From the list of visited monuments and other information available on the platform, the user can create customized routes, save them into files or print as maps for later use.