WorldWideScience

Sample records for alternative procedures approved

  1. 40 CFR 1065.12 - Approval of alternate procedures.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Approval of alternate procedures. 1065.12 Section 1065.12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Applicability and General Provisions § 1065.12 Approval...

  2. 76 FR 37014 - Expedited Approval of Alternative Test Procedures for the Analysis of Contaminants Under the Safe...

    Science.gov (United States)

    2011-06-24

    ... expedited methods approval action for determining dalapon in drinking water (75 FR 32295, June 8, 2010... the Safe Drinking Water Act; Analysis and Sampling Procedures. 75 FR 32295. June 8, 2010. List of... AGENCY 40 CFR Part 141 Expedited Approval of Alternative Test Procedures for the Analysis of...

  3. 75 FR 32295 - Expedited Approval of Alternative Test Procedures for the Analysis of Contaminants Under the Safe...

    Science.gov (United States)

    2010-06-08

    ..., 2009, Federal Register notice (74 FR 57908) (USEPA 2009b). The corrected tables are titled: Alternative... methods approval process in an April 10, 2007, Federal Register notice (72 FR 17902) (USEPA 2007) and..., Federal Register notice (73 FR 31616) (USEPA 2008) and added appendix A to 40 CFR part 141, subpart...

  4. 78 FR 32558 - Expedited Approval of Alternative Test Procedures for the Analysis of Contaminants Under the Safe...

    Science.gov (United States)

    2013-05-31

    ... Water Act; Analysis and Sampling Procedures. 74 FR 38348. August 3, 2009. USEPA. 2013. EPA Method 524.4.... Fluoride. B. Preliminary Distillation Step. C. Ion-Selective Electrode Method. D. SPADNS Method. E.... ASTM D516-02. Standard Test Method for Sulfate Ion in Water. ASTM International, 100 Barr Harbor...

  5. 12 CFR 611.510 - Approval procedures.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Approval procedures. 611.510 Section 611.510 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ORGANIZATION Transfer of Authorities § 611.510 Approval procedures. (a) Upon receipt of approval of a resolution by the Farm...

  6. 28 CFR 549.51 - Approval procedures.

    Science.gov (United States)

    2010-07-01

    ... SERVICES Plastic Surgery § 549.51 Approval procedures. The Clinical Director shall consider individually any request from an inmate or a BOP medical consultant. (a) In circumstances where plastic surgery is... forward the surgery request to the Office of Medical Designations and Transportation for approval. (b)...

  7. 29 CFR 4221.14 - PBGC-approved arbitration procedures.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false PBGC-approved arbitration procedures. 4221.14 Section 4221... LIABILITY FOR MULTIEMPLOYER PLANS ARBITRATION OF DISPUTES IN MULTIEMPLOYER PLANS § 4221.14 PBGC-approved arbitration procedures. (a) Use of PBGC-approved arbitration procedures. In lieu of the procedures...

  8. 46 CFR 162.018-8 - Procedure for approval.

    Science.gov (United States)

    2010-10-01

    ... approval of a new design or type of safety relief valve shall submit in quadruplicate detail drawings...: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Safety Relief Valves, Liquefied Compressed Gas § 162.018-8 Procedure for approval. (a) General. Safety relief valves for use on pressure vessels containing...

  9. Procedures for the approval of oil spill treatment products

    International Nuclear Information System (INIS)

    The final report of the Government Review on the Testing, Approval and Use of Oil Dispersants (MAFF, 1996) made a number of recommendations affecting approval of oil dispersants. In addition toxicity testing protocols have recently been developed to assess new types of oil treatment products such as sorbents and bioremediation agents. This document reflects these changes. It supersedes Fisheries Research Technical Report No. 39 - New procedures for the toxicity testing of oil slick dispersants (Blackman et al., 1977). Until April 1996 all toxicity assessments were carried out by the MAFF, Directorate of Fisheries Research (DFR). However, from that date appropriate toxicity testing can be carried out by suitably accredited or recognised laboratories, as an alternative to DFR, and results submitted to MAFF for consideration. This document is designed as an aid to manufacturers and potential testing laboratories. Under the scheme there is a need to assess and approve all types of oil treatment products. At present four different groups are recognised; dispersants, sorbents, bioremediation agents and miscellaneous. (author)

  10. 49 CFR 238.21 - Special approval procedure.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION PASSENGER EQUIPMENT SAFETY STANDARDS General § 238.21 Special approval procedure.... (Requests for approval of programs for the inspection, testing, and maintenance of Tier II passenger... designated representatives of its employees, together with a list of the names and addresses of the...

  11. 46 CFR 160.076-13 - Approval procedures for inflatable PFDs.

    Science.gov (United States)

    2010-10-01

    ... or construction, it is not possible for the PFD to fail that test. (g) Alternative requirements. A... of an inflatable PFD design shall follow the procedures of this section and subpart 159.005 of this... submitted to the Commandant for preapproval review. If a similar design has already been approved,...

  12. 40 CFR 86.162-00 - Approval of alternative air conditioning test simulations and descriptions of AC1 and AC2.

    Science.gov (United States)

    2010-07-01

    ... Procedures § 86.162-00 Approval of alternative air conditioning test simulations and descriptions of AC1 and AC2. The alternative air conditioning test procedures AC1 and AC2 are approved by the Administrator... requirements of paragraph (a) of this section and meet the requirements of § 86.163-00. Air conditioning...

  13. 7 CFR 1726.253 - Prior approved contract modification related to alternative bid provision for payment to...

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Modifications to RUS Standard Contract Forms § 1726.253 Prior approved contract modification related to alternative bid provision for payment to... 7 Agriculture 11 2010-01-01 2010-01-01 false Prior approved contract modification related...

  14. 46 CFR 160.176-5 - Approval procedures.

    Science.gov (United States)

    2010-10-01

    ... by design or construction the lifejacket can not fail the test. (e) Alternative requirements. A... and 159.005-7 may be omitted if a similar design has already been approved. (2) The information...) that the lifejacket is designed to provide. (ii) Any special purpose(s) for which the lifejacket...

  15. 46 CFR 160.053-6 - Procedure for approval.

    Science.gov (United States)

    2010-10-01

    ... independent laboratory accepted by the Coast Guard under 46 CFR 159.010. (c) If the work vest is of a non...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Work Vests, Unicellular Plastic Foam § 160.053-6 Procedure for... § 159.010-7 of this subchapter covering the in-water testing of personal flotation devices,...

  16. 48 CFR 852.233-71 - Alternate protest procedure.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Alternate protest... § 852.233-71 Alternate protest procedure. As prescribed in 833.106, insert the following provision: Alternate Protest Procedure (JAN 1998) As an alternative to filing a protest with the contracting...

  17. 27 CFR 22.22 - Alternate methods or procedures; and emergency variations from requirements.

    Science.gov (United States)

    2010-04-01

    ... OF TAX-FREE ALCOHOL Administrative Provisions Authorities § 22.22 Alternate methods or procedures... to the revenue; (iii) It is not contrary to law; and (iv) It will not cause an increase in cost to... are conditioned upon compliance with the conditions and limitations set forth in the approval....

  18. Performance and approval procedures for active personal dosemeters

    International Nuclear Information System (INIS)

    Active personal dosemeters (APDs) are well accepted as useful and reliable instruments for individual dosimetry measurements. The increasing concern about studying the behaviour of APDs in pulsed fields is illustrated through revision of the results of the most representative studies on the performance of APDs in the last 5 y. The deficiencies of APDs in pulsed fields are discussed together with proposals to overcome them. Although there are no legal constraints or technical limitations for recognising APDs for legal dosimetry in facilities with continuous radiation fields, APDs continue to be mainly used as operational dosemeters. The approval procedures applicable to APDs, especially the approach undertaken by Germany, are presented. Finally, some trends in the developments and use of APDs are summarised. (authors)

  19. 5 CFR 2471.6 - Investigation of request; Panel procedures; approval of binding arbitration.

    Science.gov (United States)

    2010-01-01

    ... procedures; approval of binding arbitration. 2471.6 Section 2471.6 Administrative Personnel FEDERAL LABOR... procedures; approval of binding arbitration. (a) Upon receipt of a request for consideration of an impasse... arbitration or mediation-arbitration (by a Panel designee or a private arbitrator). Following procedures...

  20. 13 CFR 134.216 - Alternative dispute resolution procedures.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Alternative dispute resolution....216 Alternative dispute resolution procedures. At any time during the pendency of a case, the parties may submit a joint motion requesting that the Judge permit the use of alternative dispute...

  1. Alternative Antimicrobial Commercial Egg Washing Procedures.

    Science.gov (United States)

    Hudson, Lauren K; Harrison, Mark A; Berrang, Mark E; Jones, Deana R

    2016-07-01

    Commercial table eggs are washed prior to packaging. Standard wash procedures use an alkaline pH and warm water. If a cool water method could be developed that would still provide a microbiologically safe egg, the industry may save energy costs associated with water heating. Four wash procedures were evaluated for Salmonella reduction: pH 11 at 48.9°C (industry standard), pH 11 at ambient temperature (∼20°C), pH 6 at 48.9°C, and pH 6 at ambient temperature. Alkaline washes contained potassium hydroxide-based detergent, while pH 6 washes contained approximately 200 ppm of chlorine and a proprietary chlorine stabilizer (T-128). When eggs were inoculated by immersion in a cell suspension of Salmonella Enteritidis and Salmonella Typhimurium, all treatments resulted in a slight and similar reduction of Salmonella numbers (approximately 0.77 log CFU/ml of shell emulsion reduction). When eggs were inoculated by droplet on the shell surface, Salmonella counts were reduced by approximately 5 log CFU when washed with chlorine plus the chlorine stabilizer at both temperatures and with the alkaline wash at the high temperature. The reductions in Salmonella by these treatments were not significantly (P > 0.05) different from each other but were significantly (P shelf life, and slow pathogen growth in and on shell eggs. PMID:27357042

  2. 6 CFR 25.9 - Procedures for certification of approved products for Homeland Security.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Procedures for certification of approved products for Homeland Security. 25.9 Section 25.9 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY REGULATIONS TO SUPPORT ANTI-TERRORISM BY FOSTERING EFFECTIVE TECHNOLOGIES § 25.9 Procedures for certification of approved...

  3. 7 CFR 322.12 - Risk assessment procedures for approving countries.

    Science.gov (United States)

    2010-01-01

    ... action. (d) We will publish a notice of availability of all completed risk assessments for public comment... 7 Agriculture 5 2010-01-01 2010-01-01 false Risk assessment procedures for approving countries... Regions § 322.12 Risk assessment procedures for approving countries. (a) The national government of...

  4. 46 CFR 162.017-6 - Procedure for approval.

    Science.gov (United States)

    2010-10-01

    ... design or type of pressure-vacuum relief valve shall submit drawings in quadruplicate showing the design... representative sample of the pressure-vacuum relief valve in each size for which approval is desired. Test...: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Valves, Pressure-Vacuum Relief, for Tank Vessels §...

  5. 75 FR 6597 - Determination to Approve Alternative Final Cover Request for the Lake County, MT Landfill...

    Science.gov (United States)

    2010-02-10

    ... requirements, Waste treatment and disposal. ] Dated: January 15, 2010. Carol Rushin, Acting Regional... to approve an alternative final cover for the Lake County landfill, a municipal solid waste landfill... Act of 1976 (RCRA), as amended by the Hazardous and Solid Waste Amendments of 1984 (HSWA),...

  6. 40 CFR 86.162-03 - Approval of alternative air conditioning test simulations.

    Science.gov (United States)

    2010-07-01

    ... alternative air conditioning test simulations. (a) Upon petition from a manufacturer or upon the Agency's own initiative, the Administrator will approve a simulation of the environmental cell for air conditioning test... the tailpipe emissions, air conditioning compressor load, and fuel economy. (2) For any...

  7. 76 FR 59421 - Proposed Information Collection; Approval Procedures for Nontoxic Shot and Shot Coatings

    Science.gov (United States)

    2011-09-26

    ... Fish and Wildlife Service Proposed Information Collection; Approval Procedures for Nontoxic Shot and Shot Coatings AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice; request for comments... shot for hunting waterfowl and coots in the United States. The regulations at 50 CFR 20.134 outline...

  8. 46 CFR 153.490 - Cargo Record Book and Approved Procedures and Arrangements Manual: Categories A, B, C, and D.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo Record Book and Approved Procedures and... Cargo Record Book and Approved Procedures and Arrangements Manual: Categories A, B, C, and D. (a) Unless... carry NLS cargo, a ship must have— (1) If U.S., a Cargo Record Book published by the Coast Guard...

  9. A Schwarz alternating procedure for singular perturbation problems

    Energy Technology Data Exchange (ETDEWEB)

    Garbey, M. [Universit Claude Bernard Lyon, Villeurbanne (France); Kaper, H.G. [Argonne National Lab., IL (United States)

    1994-12-31

    The authors show that the Schwarz alternating procedure offers a good algorithm for the numerical solution of singular perturbation problems, provided the domain decomposition is properly designed to resolve the boundary and transition layers. They give sharp estimates for the optimal position of the domain boundaries and present convergence rates of the algorithm for various second-order singular perturbation problems. The splitting of the operator is domain-dependent, and the iterative solution of each subproblem is based on a modified asymptotic expansion of the operator. They show that this asymptotic-induced method leads to a family of efficient massively parallel algorithms and report on implementation results for a turning-point problem and a combustion problem.

  10. Analysis of generalized Schwarz alternating procedure for domain decomposition

    Energy Technology Data Exchange (ETDEWEB)

    Engquist, B.; Zhao, Hongkai [Univ. of California, Los Angeles, CA (United States)

    1996-12-31

    The Schwartz alternating method(SAM) is the theoretical basis for domain decomposition which itself is a powerful tool both for parallel computation and for computing in complicated domains. The convergence rate of the classical SAM is very sensitive to the overlapping size between each subdomain, which is not desirable for most applications. We propose a generalized SAM procedure which is an extension of the modified SAM proposed by P.-L. Lions. Instead of using only Dirichlet data at the artificial boundary between subdomains, we take a convex combination of u and {partial_derivative}u/{partial_derivative}n, i.e. {partial_derivative}u/{partial_derivative}n + {Lambda}u, where {Lambda} is some {open_quotes}positive{close_quotes} operator. Convergence of the modified SAM without overlapping in a quite general setting has been proven by P.-L.Lions using delicate energy estimates. The important questions remain for the generalized SAM. (1) What is the most essential mechanism for convergence without overlapping? (2) Given the partial differential equation, what is the best choice for the positive operator {Lambda}? (3) In the overlapping case, is the generalized SAM superior to the classical SAM? (4) What is the convergence rate and what does it depend on? (5) Numerically can we obtain an easy to implement operator {Lambda} such that the convergence is independent of the mesh size. To analyze the convergence of the generalized SAM we focus, for simplicity, on the Poisson equation for two typical geometry in two subdomain case.

  11. Approval procedures for clinical trials in the field of radiation oncology

    International Nuclear Information System (INIS)

    Application of ionizing radiation for the purpose of medical research in Germany needs to be approved by the national authority for radiation protection (Bundesamt fuer Strahlenschutz, BfS). For studies in the field of radiation oncology, differentiation between use of radiation for ''medical care (Heilkunde)'' versus ''medical research'' frequently leads to contradictions. The aim of this article is to provide principle investigators, individuals, and institutions involved in the process, as well as institutional review or ethics committees, with the necessary information for this assessment. Information on the legal frame and the approval procedures are also provided. A workshop was co-organized by the German Society for Radiation Oncology (DEGRO), the Working Party for Radiation Oncology (ARO) of the German Cancer Society (DKG), the German Society for Medical Physics (DGMP), and the German Cancer Consortium (DKTK) in October 2013. This paper summarizes the results of the workshop and the follow-up discussions between the organizers and the BfS. Differentiating between ''Heilkunde'' which does not need to be approved by the BfS and ''medical research'' is whether the specific application of radiation (beam quality, dose, schedule, target volume, etc.) is a clinically established and recognized procedure. This must be answered by the qualified physician(s) (''fachkundiger Arzt'' according to German radiation protection law) in charge of the study and the treatments of the patients within the study, taking into consideration of the best available evidence from clinical studies, guidelines and consensus papers. Among the important parameters for assessment are indication, total dose, and fractionation. Radiation treatments applied outside clinical trials do not require approval by the BfS, even if they are applied within a randomized or nonrandomized clinical trial

  12. 25 CFR 170.934 - Are alternative dispute resolution procedures available?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Are alternative dispute resolution procedures available... alternative dispute resolution (ADR) procedures is to provide an inexpensive and expeditious forum to resolve... (including for non-construction the mediation and alternative dispute resolution options listed in 25...

  13. 16 CFR 1630.62 - Wool flokati carpets and rugs-alternative washing procedure.

    Science.gov (United States)

    2010-01-01

    ...(a) and 1 CFR part 51. Alternatively the selected sample or oversized specimens thereof may be washed... washing procedure. 1630.62 Section 1630.62 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION...) Washing Procedures § 1630.62 Wool flokati carpets and rugs—alternative washing procedure. (a) The...

  14. 16 CFR 1631.62 - Wool flokati carpets and rugs-alternative washing procedure.

    Science.gov (United States)

    2010-01-01

    ...(a) and 1 CFR part 51. Alternatively the selected sample or oversized specimens thereof may be washed... washing procedure. 1631.62 Section 1631.62 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION...) Washing Procedures § 1631.62 Wool flokati carpets and rugs—alternative washing procedure. (a) The...

  15. Decisions in licensing and plan approval procedures, investigated from the viewpoint of legal reservation

    International Nuclear Information System (INIS)

    Starting from the basic idea that also in the field of environmental law, (constitutional) system immanent problem solution is possible only after basic constitutional questions have been clarified, this study in hand is an attempt towards defining the constitutional approach for an adequate use of the various types of action of the executive in the procedures for approval and licensing of privately owned plant or equipment. The study goes into the problems encountered with the legal reservation with regard to licensing and plan approval decisions. The basic types of action of the executive are subdivided according to intent, i.e. assigned to the supervisory or the planning intents, and are examined for a possible scope of discretion opened up for the administration. The decisive question in this context is the scope of action that may be given to the administration by the legislation, and to what extent such 'freedom' will stand the acceptance test by the courts. (orig./HSCH)

  16. Preliminary decision and construction design approval in the nuclear licensing procedure from the view of the energy supply enterprises

    International Nuclear Information System (INIS)

    From the point of view of the supply enterprises, a site plan approval procedure for nuclear facilities is a pressing need for long-term site provision, because the preliminary decision has not proven useful as a means of clarifying the site situation. Construction design approval, based on nuclear law, from the point of view of the supply enterprises, is a very desirable instrument for standardizing nuclear facilities and thus for speeding up the licensing procedures. (orig.)

  17. Is suvorexant a better choice than alternative hypnotics? [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Daniel F. Kripke

    2015-08-01

    Full Text Available Suvorexant is a novel dual orexin receptor antagonist (DORA newly introduced in the U.S. as a hypnotic, but no claim of superiority over other hypnotics has been offered.  The manufacturer argued that the 5 and 10 mg starting doses recommended by the FDA might be ineffective.  The manufacturer's main Phase III trials had not even included the 10 mg dosage, and the 5 mg dosage had not been tested at all in registered clinical trials at the time of approval.  Popular alternative hypnotics may be similarly ineffective, since the FDA has also reduced the recommended doses for zolpidem and eszopiclone.  The "not to exceed" suvorexant dosage of 20 mg does slightly increase sleep.  Because of slow absorption, suvorexant has little effect on latency to sleep onset but some small effect in suppressing wakening after sleep onset and in improving sleep efficiency. The FDA would not approve the manufacturer's preferred 40 mg suvorexant dosage, because of concern with daytime somnolence, driving impairment, and possible narcolepsy-like symptoms.  In its immediate benefits-to-risks ratio, suvorexant is unlikely to prove superior to currently available hypnotics—possibly worse—so there is little reason to prefer over the alternatives this likely more expensive hypnotic less-tested in practice.  Associations are being increasingly documented relating hypnotic usage with incident cancer, with dementia risks, and with premature death.  There is some basis to speculate that suvorexant might be safer than alternative hypnotics in terms of cancer, dementia, infections, and mortality.  These safety considerations will remain unproven speculations unless adequate long-term trials can be done that demonstrate suvorexant advantages.

  18. 7 CFR 932.130 - Public member and alternate public member eligibility requirements and nomination procedures.

    Science.gov (United States)

    2010-01-01

    ... alternate public member. (3) A majority vote is required in Committee actions concerning the nomination of... requirements and nomination procedures. 932.130 Section 932.130 Agriculture Regulations of the Department of... member and alternate public member eligibility requirements and nomination procedures. (a)...

  19. Unions and Procedural Justice: An Alternative to the Common Rule

    OpenAIRE

    Marsden, David

    2004-01-01

    Can unions substitute a procedural justice role for their traditional reliance on establishing a ‘common rule’? The decline of ‘bureaucratic’ models of employee management and the rise of performance pay and performance management conflicts with the common rule as management seek to tie rewards more closely to individual and organisational performance. CEP studies of performance pay in the British public services illustrate the potential for a procedural justice role to ensure that such pay s...

  20. 16 CFR 1631.61 - Hide carpets and rugs-alternative washing procedure.

    Science.gov (United States)

    2010-01-01

    ... approved by the Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Hide carpets and rugs-alternative washing... ACT REGULATIONS STANDARD FOR THE SURFACE FLAMMABILITY OF SMALL CARPETS AND RUGS (FF 2-70)...

  1. 16 CFR 1630.61 - Hide carpets and rugs-alternative washing procedure.

    Science.gov (United States)

    2010-01-01

    ... approved by the Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Hide carpets and rugs-alternative washing... ACT REGULATIONS STANDARD FOR THE SURFACE FLAMMABILITY OF CARPETS AND RUGS (FF 1-70) Washing...

  2. 75 FR 50930 - Final Determination To Approve Alternative Final Cover Request for the Lake County, Montana Landfill

    Science.gov (United States)

    2010-08-18

    ... cover for the Lake County landfill, a municipal solid waste landfill (MSWLF) owned and operated by Lake... approve in the Federal Register on February 10, 2010, (75 FR 6597) Lake County's site-specific flexibility... install an alternative final landfill cover that meets the requirements of 40 CFR 258.60(b). The...

  3. Alternative Modal Basis Selection Procedures for Nonlinear Random Response Simulation

    Science.gov (United States)

    Przekop, Adam; Guo, Xinyun; Rizzi, Stephen A.

    2010-01-01

    Three procedures to guide selection of an efficient modal basis in a nonlinear random response analysis are examined. One method is based only on proper orthogonal decomposition, while the other two additionally involve smooth orthogonal decomposition. Acoustic random response problems are employed to assess the performance of the three modal basis selection approaches. A thermally post-buckled beam exhibiting snap-through behavior, a shallowly curved arch in the auto-parametric response regime and a plate structure are used as numerical test articles. The results of the three reduced-order analyses are compared with the results of the computationally taxing simulation in the physical degrees of freedom. For the cases considered, all three methods are shown to produce modal bases resulting in accurate and computationally efficient reduced-order nonlinear simulations.

  4. Electrical stimulation for difficult wounds: only an alternative procedure?

    Science.gov (United States)

    Fraccalvieri, Marco; Salomone, Marco; Zingarelli, Enrico M; Rivarossa, Filippo; Bruschi, Stefano

    2015-12-01

    In the wound healing research, the exact mechanism of action of different modalities of electrical stimulation (ES) remains controversial and unresolved. In this study we discuss a particular ES, with a different type of waveform, corresponding to the principle of stochastic resonance. Between July 2008 and May 2010, 32 patients were enrolled and ES was applied to wounds using the bioelectrical signal therapy (BST) device (LifeWave, Petach Tiqwa, Israel). The outcome evaluated in group 1 (n = 21) was wound healing, while group 2 (n = 11) was evaluated for wound-related pain [Visual Number Scale (VNS) pain scale] during treatment. In group 1, 87% of the wounds closed in an average time of 97 days (range 10-150 days); three patients were lost to follow-up. In group 2, 45% of the patients experienced a complete pain disappearance after 7 days of treatment; 36% reported a reduction in VNS from 9·3 to 3·2 in 7 days; 19% stopped morphine-like painkillers after 2 weeks. The clinical application of the stochastic resonance enables the usage of easy-to-use, non-invasive, painless and pain-relief treatment. Our experience with ES has demonstrated the BST device to be a very good alternative in cases of small size defects, compared with other therapies such as surgery, dressing and negative pressure devices. PMID:24443795

  5. 33 CFR 241.5 - Procedures for estimating the alternative cost-share.

    Science.gov (United States)

    2010-07-01

    ... alternative cost-share. 241.5 Section 241.5 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE FLOOD CONTROL COST-SHARING REQUIREMENTS UNDER THE ABILITY TO PAY PROVISION § 241.5 Procedures for estimating the alternative cost-share. (a) Step one, the benefits...

  6. Alternative procedure to determine radionuclide concentrations for marine sediment dating

    International Nuclear Information System (INIS)

    The development of an alternative method to prepare and to measure marine sediment samples for dating purpose using high resolution gamma spectrometry is given. To calculate the 137 Cs and the supported and unsupported 210 Pb concentrations, cylindrical tablets subjected to different pressures were analyzed. Mass attenuation coefficients (MAC) were determined by our variant of the transmission method, the Bragg law (using MACs provided by the web program XCOM) and the method of average composition of the analyzed sediment samples. The differences between obtained results are smaller than the experimental error (10%). The influence of pressure and sediment mass on the MAC, mechanical stability of the sample, and self-absorption corrections for different gamma energies is studied. Optimal dimensions of the tablets were determined from considerations on the infinite thickness, minimum detectable activity, precision of results, radiation self-absorption and geometric efficiency. Based on the differential peak absorption analysis, through a relative efficiency curve, a new method to evaluate the existence of radioactive equilibrium between 226 Ra, 222 Rn and its progeny is given. Experimental error of the proposed methodology is evaluated, as well as accuracy, precision and detection limit. With the use of developed methodology, the 210 Pb, 226 Ra and 137 Cs activities in recent sediment samples from near shore of the Orinoco River Delta were determined. The results were comparable with the obtained by two of the most used methods, while precision is improved and radiation self-absorption in sample container is avoided since sample encapsulation is not required. (Full Text)

  7. 77 FR 68784 - Standard Test Procedures Approval Process for Respirators To Be Used in Wildland Fire-Fighting...

    Science.gov (United States)

    2012-11-16

    ... developed respiratory protection for this occupational setting, firefighters battling wild fires often... Respirators To Be Used in Wildland Fire-Fighting Operations; Standard Test Procedures for Composite Multi-Gas and Particulate Protection and Approval Process for Respirators To Be Used in Wildland...

  8. 7 CFR 1948.82 - Plan and State Investment Strategy approval procedure.

    Science.gov (United States)

    2010-01-01

    ... hired in coal or uranium development activities in each of the next three years within the approved... Impacted Area Development Assistance Program § 1948.82 Plan and State Investment Strategy approval... production, processing, or transportation in each of the next three calendar years within the area covered...

  9. 75 FR 53371 - Liquefied Natural Gas Facilities: Obtaining Approval of Alternative Vapor-Gas Dispersion Models

    Science.gov (United States)

    2010-08-31

    ... Pipeline and Hazardous Materials Safety Administration Liquefied Natural Gas Facilities: Obtaining Approval... Safety Administration (PHMSA) issues federal safety standards for siting liquefied natural gas (LNG...) NFPA 59A: Standard for the Production, Storage, and Handling of Liquefied Natural Gas. That...

  10. 40 CFR Appendix D to Part 63 - Alternative Validation Procedure for EPA Waste and Wastewater Methods

    Science.gov (United States)

    2010-07-01

    ... validated according to the procedures in Sections 5.1 and 5.3 of Test Method 301, 40 CFR part 63, appendix A... Method 25D of 40 CFR part 60, appendix A. 2.1. Sampling and Analysis 2.1.1. For each waste matrix... 40 Protection of Environment 14 2010-07-01 2010-07-01 false Alternative Validation Procedure...

  11. Mediation and Other Alternative Dispute Resolution Procedures in Special Education. Final Report.

    Science.gov (United States)

    Schrag, Judy A.

    This report discusses the use of mediation and alternative dispute resolution approaches in special education disagreements between the school and the parents of a child with a disability. The procedural safeguards and due process provisions of the Individuals with Disabilities Education Act (IDEA) are explained. The report notes alternative…

  12. Evaluation of alternative surface runoff accounting procedures using the SWAT model

    Science.gov (United States)

    For surface runoff estimation in the Soil and Water Assessment Tool (SWAT) model, the curve number (CN) procedure is commonly adopted to calculate surface runoff by utilizing antecedent soil moisture condition (SCSI) in field. In the recent version of SWAT (SWAT2005), an alternative approach is ava...

  13. 48 CFR 2052.215-78 - Travel approvals and reimbursement-Alternate 1.

    Science.gov (United States)

    2010-10-01

    ... expenditure for travel may not exceed ___ * ___ without the prior approval of the contracting officer. (b) All... institutional policy to the degree that the limitations of Office of Management and Budget (OMB) guidance are... Local Governments; OMB Circular A-122, Cost Principles for Nonprofit Organizations; and OMB Circular...

  14. Alternate approaches for pediatric type 1 diabetes drug development and potential regulatory approval: a perspective.

    Science.gov (United States)

    Turner, J Rick; Close, Kelly L; Fleming, G Alexander; Wherrett, Diane K; DiMeglio, Linda A

    2015-10-01

    The incidence and prevalence of pediatric type 1 diabetes are increasing globally, including in the U.S. While the increasing number of cases of pediatric diabetes makes expeditious availability of new medical products and therapies for diabetes care essential, there have been many barriers encountered in bringing some drugs and devices to pediatric patients who may benefit. Newer insulins have been studied and approved for use in children. However, hurdles exist in the inclusion of children in studies of therapies aimed at preventing β-cell loss in those with new-onset diabetes and those at risk for type 1 diabetes. This Perspective focuses on potential solutions to the challenges experienced in bringing new drugs for pediatric type 1 diabetes to marketing approval. Given their central importance as the users of medical products, patient perspectives are included along with scientific and regulatory considerations. PMID:26404928

  15. 28 CFR 58.26 - Procedures for inclusion on the approved provider list.

    Science.gov (United States)

    2010-07-01

    ... to, changes in the location of primary or satellite business office(s); the principal contact person; name or fictitious name under which the provider does business; management, including the board of directors; and a merger or consolidation with another entity; (2) The provider shall request approval...

  16. 15 CFR 923.133 - Procedure for conducting continuing reviews of approved State CZM programs.

    Science.gov (United States)

    2010-01-01

    ... approved CZM program; (B) The management agency is effectively playing a leadership role in coastal issues..., DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS... performance of coastal States with respect to coastal management. Each review shall include a...

  17. Procedure for getting safety classed concrete structures approved by Finnish Radiation and Nuclear Safety Authority

    International Nuclear Information System (INIS)

    Posiva is preparing geological final disposal in the Finnish bedrock in Olkiluoto, Eurajoki. The final disposal facility includes encapsulation plant and underground repository. Most of the main civil structures are concrete structures. STUK is the supervising authority in civil structures. The National Building Code of Finland and STUK's Regulatory Guide on nuclear safety (YVL) are the most important instructions when constructing concrete structures into nuclear installation. Posiva has classified concrete structures in two classes according STUK's YVL-guidance: EYT (non-nuclear) and Safety Class 3 (SC 3, nuclear safety significance). When building SC 3 concrete structures, specific protocol must be followed. Protocol includes planned routines for design, construction, supervision, quality control (QC) and quality assurance (QA) activities. Documents relating concrete structures must be approved by Posiva and STUK before construction work. After structures have been designed and actual building is ongoing, there are two main steps. Before concreting, readiness inspection for concreting must be arranged. Readiness inspection will be arranged according to a specific plan and the date must be informed to STUK. After establishing readiness for concreting, casting work can begin. Once concrete structures are done, inspected and approved, final documentation according to a quality control plan will be reviewed by Posiva. After Posiva's approval, final documentation will be sent for STUK's approval. In the end STUK will give the permission for commissioning of the concrete structures after approved commissioning inspection. The document is made up of an abstract and a poster

  18. Comparative cost analysis -- computed tomography vs. alternative diagnostic procedures, 1977-1980

    International Nuclear Information System (INIS)

    In comparing the total national cost of utilizing computed tomography (CT) for medically indicated diagnoses with that of conventional x-ray, ultrasonography, nuclear medicine, and exploratory surgery, this investigation concludes that there was little, if any, added net cost from CT use in 1977 or will there be in 1980. Computed tomography, generally recognized as a reliable and useful diagnostic modality, has the potential to reduce net costs provided that an optimal number of units can be made available to physicians and patients to achieve projected reductions in alternative procedures. This study examines the actual cost impact of CT on both cranial and body diagnostic procedures. For abdominal and mediastinal disorders, CT scanning is just beginning to emerge as a diagnostic modality. As such, clinical experience is somewhat limited and the authors assume that no significant reduction in conventional procedures took place in 1977. It is estimated that the approximately 375,000 CT body procedures performed in 1977 represent only a 5 percent cost increase over use of other diagnostic modalities. It is projected that 2,400,000 CT body procedures will be performed in 1980 and, depending on assumptions used, total body diagnostic costs will increase only slightly or be reduced. Thirty-one tables appear throughout the text presenting cost data broken down by types of diagnostic procedures used and projections by years. Appendixes present technical cost components for diagnostic procedures, the comparative efficacy of CT as revealed in abstracts of published literature, selected medical diagnoses, and references

  19. Factors Influencing Approval Probability in Austrian Science Fund (FWF) Decision-Making Procedures - FWF Stand-Alone Projects Programme, 1999 to 2008

    OpenAIRE

    Reckling, Falk; Fischer, Christian

    2010-01-01

    The legitimacy of decision-making procedures (peer review) at funding agencies for basic research depends heavily on the organisation’s ability to minimise distortions in approval probability – for example based on age, gender or research field – wherever possible. Due to human fallibility, erroneous decisions can never be ruled out entirely, but if systematic differences appear in the probability of funding approvals, then such differences either have to be eliminated by ch...

  20. The Role of the Approval Procedure of Economic and Social Activities with Environmental Impact

    OpenAIRE

    Brasoveanu Florica

    2013-01-01

    Starting from the idea that it is better to prevent environmental damage than to repair the damage already caused, the state introduced the environmental impact assessment procedure of economic and social activities as the basis for their authorization and operation. Evaluation of potential environmental consequences and, on this basis, the development of measures aimed at eliminating or reducing their allowable limits, have become compulsory for socialeconomic activities so that future gener...

  1. Alternative procedure for the fabrication of close-spaced sublimated CdTe solar cells

    International Nuclear Information System (INIS)

    We deposited CdTe thin films by close-spaced sublimtation using an alternative procedure, with temperatures about 170 degree sign C lower than the ones used in the standard procedure. These films were used in the fabrication of all thin-film CdTe/CdS solar cells. We treated the cells using the well-established CdCl2 dipping process as well as a new vapor treatment. The vapor process was more reproducible and easier to control, and it produced the best devices. This process was also much more effective in the recrystallization of the CdTe films. The best device that we produced had an efficiently of 11.6%, close to the 12.3% efficiency of the best device fabricated using the standard process. These results show that the new process has good potential, and besides being an alternative for lower-cost solar cell production, it can also produce high-efficiency devices. (c) 2000 American Vacuum Society

  2. PREVENTIVE AGREEMENT – THE VIABLE ALTERNATIVE TO LAW NO. 85/2006 ON INSOLVENCY PROCEDURE?

    Directory of Open Access Journals (Sweden)

    PAULINA DINA

    2011-04-01

    Full Text Available Given the economic crisis that Romania is going through and which influenced in a negative manner the activity of economic agents throughout the country, Law no. 381/2009 has been adopted for the implementation of the preventive agreement and ad-hoc mandate, in order to support companies facing economic difficulties in their activity. Law no. 381/2009 became applicable on January 13, 2010 and it implements, as an alternative to the difficult and time-consuming procedure of insolvency, a contractual mechanism for companies facing difficulties in organizing their activities, outside the insolvency procedure, with limited involvement from the court. This regulation is seen as a solution against the opening of the insolvency procedure. The solution applies especially to small and middle sized companies. The preventive agreement implies a longer deadline for payment liabilities based on a friendly agreement with the creditors. It is a mechanism for avoiding insolvency and it consists of an agreement made between the debtor and the creditors regarding the way in which the debtor, which is in a difficult financial position, will pay all its outstanding debts. The law applies to all legal entities which reorganize a company going through a difficult financial period, without being in insolvency and which are called debtors. Nevertheless, the preventive agreement law still forces us to relate to the notion of insolvency.

  3. On the Physical Problem of Spatial Dimensions: An Alternative Procedure to Stability Arguments

    CERN Document Server

    Caruso, Francisco

    2012-01-01

    Why is space 3-dimensional? The first answer to this question, entirely based on Physics, was given by Ehrenfest, in 1917, who showed that the stability requirement for $n$-dimensional two-body planetary system very strongly constrains space dimensionality, favoring 3-d. This kind of approach will be generically called "stability postulate" throughout this paper and was shown by Tangherlini, in 1963, to be still valid in the framework of general relativity as well as for quantum mechanical hydrogen atom, giving the same constraint for space-dimensionality. In the present work, before criticizing this methodology, a brief discussion has been introduced, aimed at stressing and clarifying some general physical aspects of the problem of how to determine the number of space dimensions. Then, the epistemological consequences of Ehrenfest's methodology are critically reviewed. An alternative procedure to get at the proper number of dimensions, in which the stability postulate (and the implicit singularities in three...

  4. Approval procedures for clinical trials in the field of radiation oncology; Genehmigungsverfahren klinischer Studien im Bereich der Radioonkologie

    Energy Technology Data Exchange (ETDEWEB)

    Simon, Monique; Buettner, Daniel [Deutsches Konsortium fuer Translationale Krebsforschung (DKTK), Dresden (Germany); Deutsches Krebsforschungszentrum (DKFZ), Heidelberg (Germany); Medizinische Fakultaet und Universitaetsklinikum Carl Gustav Carus, Technische Universitaet Dresden, Klinik fuer Strahlentherapie und Radioonkologie und OncoRay - Nationales Zentrum fuer Strahlenforschung in der Onkologie, Dresden (Germany); Habeck, Matthias; Habeck, Uta; Brix, Gunnar [Bundesamt fuer Strahlenschutz (BfS), Fachbereich Strahlenschutz und Gesundheit, Neuherberg (Germany); Krause, Mechthild; Baumann, Michael [Deutsches Konsortium fuer Translationale Krebsforschung (DKTK), Dresden (Germany); Deutsches Krebsforschungszentrum (DKFZ), Heidelberg (Germany); Medizinische Fakultaet und Universitaetsklinikum Carl Gustav Carus, Technische Universitaet Dresden, Klinik fuer Strahlentherapie und Radioonkologie und OncoRay - Nationales Zentrum fuer Strahlenforschung in der Onkologie, Dresden (Germany); Helmholtz-Zentrum Dresden - Rossendorf, Institut fuer Radioonkologie und OncoRay - Nationales Zentrum fuer Strahlenforschung in der Onkologie, Dresden (Germany); Willich, Normann [Universitaetsklinikum Muenster, Klinik fuer Strahlentherapie - Radioonkologie, Muenster (Germany); Wenz, Frederik [Universitaetsmedizin Mannheim, Medizinische Fakultaet Mannheim, Universitaet Heidelberg, Klinik fuer Strahlentherapie und Radioonkologie, Mannheim (Germany); Schmidberger, Heinz [Universitaetsmedizin Mainz, Klinik fuer Radioonkologie und Strahlentherapie, Mainz (Germany); Debus, Juergen [Universitaetsklinikum Heidelberg, Klinik fuer Radioonkologie und Strahlentherapie, Heidelberg (Germany); Noelling, Torsten

    2015-12-15

    Application of ionizing radiation for the purpose of medical research in Germany needs to be approved by the national authority for radiation protection (Bundesamt fuer Strahlenschutz, BfS). For studies in the field of radiation oncology, differentiation between use of radiation for ''medical care (Heilkunde)'' versus ''medical research'' frequently leads to contradictions. The aim of this article is to provide principle investigators, individuals, and institutions involved in the process, as well as institutional review or ethics committees, with the necessary information for this assessment. Information on the legal frame and the approval procedures are also provided. A workshop was co-organized by the German Society for Radiation Oncology (DEGRO), the Working Party for Radiation Oncology (ARO) of the German Cancer Society (DKG), the German Society for Medical Physics (DGMP), and the German Cancer Consortium (DKTK) in October 2013. This paper summarizes the results of the workshop and the follow-up discussions between the organizers and the BfS. Differentiating between ''Heilkunde'' which does not need to be approved by the BfS and ''medical research'' is whether the specific application of radiation (beam quality, dose, schedule, target volume, etc.) is a clinically established and recognized procedure. This must be answered by the qualified physician(s) (''fachkundiger Arzt'' according to German radiation protection law) in charge of the study and the treatments of the patients within the study, taking into consideration of the best available evidence from clinical studies, guidelines and consensus papers. Among the important parameters for assessment are indication, total dose, and fractionation. Radiation treatments applied outside clinical trials do not require approval by the BfS, even if they are applied within a randomized or nonrandomized clinical trial

  5. 26 CFR 1.23-6 - Procedure and criteria for additions to the approved list of energy-conserving components or...

    Science.gov (United States)

    2010-04-01

    ... approved list of energy-conserving components or renewable energy sources. 1.23-6 Section 1.23-6 Internal...-conserving components or renewable energy sources. (a) Procedures for additions to the list of energy-conserving components or renewable energy sources—(1) In general. A manufacturer of an item (or a group...

  6. On the scope of the Federal Government to issue orders in plan approval procedures under para. 9b of the Atomic Energy Act as provided by article 85 section 3 of the Basic Law

    International Nuclear Information System (INIS)

    Under Paragraph 9b of the Atomic Energy Act the Lower Saxonian Minister of the Environment has the competence for the plan approval procedure concerning the final disposal site Konrad. The plan approval procedure under atomic energy law is a unitary administrative procedure which makes further administrative procedures and administrative decisions superfluous on the strength of its unitary character and without impingement on constitutional law. In conducting the plan approval procedure the Lower Saxonican Minister of the Environment is acting within the framework of Laender administration on behalf of the Federation. To this extent he is subject to the orders of the Federal Minister of the Enviroment under Article 85 Section 3 of The Basic Law with respect to the formation of the procedure and procedural decisions as well as decisions on the merits pending. The concentrating effect of the plan approval procedure under atomic energy law also extends to permits under water law. (orig./HSCH)

  7. Alternative procedure to shorten rectal barostat procedure for the assessment of rectal compliance and visceral perception: a feasibility study

    OpenAIRE

    Vanhoutvin, S.A.L.W.; Troost, F. J; Kilkens, T. O. C.; Lindsey, P. J.; Jonkers, D.M.A.E.; Venema, K.; Masclee, A.; Brummer, R-J M

    2012-01-01

    Background Barostat methodology is widely used for assessing visceral perception. Different barostat protocols are described with respect to the measurement of rectal compliance and visceral perception. The choice of protocols affects the duration, which is normally 60–90 min, and accuracy of the procedure. This study aimed to shorten the procedure by using the semi-random distension protocol for both compliance and visceral perception measurement and a correction based on rectal capacity (RC...

  8. 40 CFR 403.11 - Approval procedures for POTW pretreatment programs and POTW granting of removal credits.

    Science.gov (United States)

    2010-07-01

    ... denying requests for approval of POTW Pretreatment Programs and applications for removal credit... public notice of any Submission complying with the requirements of § 403.9(b) and, where removal credit... removal credit authorization is sought, with § 403.7. The Approval Authority may have up to an...

  9. European type-approval test procedure for evaporative emissions from passenger cars against real-world mobility data from two Italian provinces

    OpenAIRE

    MARTINI Giorgio; PAFFUMI Elena; DE GENNARO MICHELE; MELLIOS Giorgos

    2014-01-01

    This paper presents an evaluation of the European type-approval test procedure for evaporative emissions from passenger cars based on real-world mobility data. The study relies on two large databases of driving patterns from conventional fuel vehicles collected by means of on-board GPS systems in the Italian provinces of Modena and Firenze. Approximately 28,000 vehicles were monitored, corresponding to approximately 36 million kilometres over a period of one month. The driving pat...

  10. Decree of the State Office for Nuclear Safety No. 142/1997 of 17 June 1997 on type approval procedures for packagings designed for the transport, storage or disposal of radionuclide sources of radiation and/or nuclear materials, type approval procedures for ionizing radiation sources, and type approval procedures for protective devices for ionizing radiation source handling and for other facilities for ionizing radiation source handling (the Type Approval Procedure Decree)

    International Nuclear Information System (INIS)

    The Decree dealing with the title topics defines the basic terms including the various types of packaging, specifies which types of packaging are subject to type approval, lays down requirements for type approval applications and testing documentation, specifies items which will be stated in the type approval document, and describes the scope of compliance verification. The following Annexes are included: (1) low-specific-activity radionuclide emitters and surface contaminated objects; (2) generic requirements for packagings; (3) requirements for Type PZ-1, PZ-2 and PZ-3 packagings; (4) table of A1 and A2 activity values; (5) requirements for Type A and Type B packagings; (6) additional requirements for Type B packagings; (7) requirements for Type S packagings; (8) requirements for packagings designed for the transport, storage and/or disposal of special fissile materials and plutonium-241; and (9) packaging testing. (P.A.)

  11. 21 CFR 314.54 - Procedure for submission of an application requiring investigations for approval of a new...

    Science.gov (United States)

    2010-04-01

    ..., or sale of the drug product. (vi) Any patent certification or statement required under section 505(b... requiring investigations for approval of a new indication for, or other change from, a listed drug. 314.54 Section 314.54 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  12. Amendment to the agreement between CERN and Ukraine concerning the granting of the status of Associate Member at CERN Extension of the deadline for the notification of the completion of the internal approval procedures of the agreement by Ukraine

    CERN Document Server

    2015-01-01

    Amendment to the agreement between CERN and Ukraine concerning the granting of the status of Associate Member at CERN Extension of the deadline for the notification of the completion of the internal approval procedures of the agreement by Ukraine

  13. 78 FR 37463 - Expedited Approval of Alternative Test Procedures for the Analysis of Contaminants Under the Safe...

    Science.gov (United States)

    2013-06-21

    .......... 9223 B 9223 B 9223 B 9223 B-97......... Readycult . Ready cult \\20\\ Colitag Modified ColitagTM \\13\\ Chromocult Chromo cult \\21\\ EC-MUG 9221 F Enterococci Multiple-Tube 9230 B-04......... Technique....

  14. 77 FR 38523 - Expedited Approval of Alternative Test Procedures for the Analysis of Contaminants Under the Safe...

    Science.gov (United States)

    2012-06-28

    ....standardmethods.org .) ASTM International. 1999. ASTM D1179-99 B. Standard Test Methods for Fluoride Ion in Water... International. 2010b. ASTM D1179-10 B. Standard Test Methods for Fluoride Ion in Water. ASTM International, 100... SPADNS 2 (Arsenic-free) Fluoride Method 10225--Spectrophotometric Measurement of Fluoride in Water......

  15. A comparative assessment of alternative waste management procedures for selected reprocessing wastes

    International Nuclear Information System (INIS)

    This report, which has been prepared by Associated Nuclear Services for the Department of the Environment, presents the results of a study and comparative assessment of management procedures for low and intermediate level solid waste streams arising from current and future fuel reprocessing operations on the Sellafield site. The characteristics and origins of the wastes under study are discussed and a reference waste inventory is presented, based on published information. Waste management strategy in the UK and its implications for waste conditioning, packaging and disposal are discussed. Wastes currently arising which are not suitable for Drigg burial or sea dumping are stored in an untreated form. Work is in hand to provide additional and improved disposal facilities which will accommodate all the waste streams under study. For each waste stream viable procedures are identified for further assessment. The procedures comprise a series of on-site operations-recovery from storage, pre-treatment, treatment, encapsulation, and packaging, prior to storage or disposal of the conditioned waste form. Assessments and comparisons of each procedure for each waste are presented. These address various process, operational, economic, radiological and general safety factors. The results are presented in a series of tables with supporting text. For the majority of wastes direct encapsulation with minimal treatment appears to be a viable procedure. Occupational exposure and general safety are not identified as significant factors governing the choice of procedures. The conditioned wastes meet the general requirements for safe handling during storage and transportation. The less active wastes suitable for disposal by currently available routes meet the appropriate disposal criteria. It is not possible to consider in detail the suitability for disposal of the more active wastes for which disposal facilities are not yet available. (Author)

  16. The marginal cost of justice: a theory of optimal use of alternative criminal procedures

    Czech Academy of Sciences Publication Activity Database

    Dušek, Libor; Montag, J.

    Vienna : European Association of Law and Economics (EALE), 2015, s. 1-30. [Annual Conference of the European Association of Law and Economics (EALE) /32./. Vienna (AT), 17.9.2015-19.9.2015] Institutional support: RVO:67985998 Keywords : criminal procedure * law enforcement * legal process Subject RIV: AH - Economics http://eale.org/content/uploads/2015/08/criminalprocedureeale.pdf

  17. 40 CFR 80.128 - Alternative agreed upon procedures for refiners and importers.

    Science.gov (United States)

    2010-07-01

    ... blender designating the required blending procedures, or that the refiner or importer accounted for the... importer's downstream oxygenated blender quality assurance program with the sampling and testing rates as...: (i) Determine if the refiner or importer had a contract in place with the downstream blender...

  18. Alternative Procedures for Reducing Allogeneic Blood Transfusion in Elective Orthopedic Surgery

    OpenAIRE

    Kleinert, Kathrin; Theusinger, Oliver M.; Nuernberg, Johannes; Werner, Clément M. L.

    2010-01-01

    Perioperative blood loss is a major problem in elective orthopedic surgery. Allogeneic transfusion is the standard treatment for perioperative blood loss resulting in low postoperative hemoglobin, but it has a number of well-recognized risks, complications, and costs. Alternatives to allogeneic blood transfusion include preoperative autologous donation and intraoperative salvage with postoperative autotransfusion. Orthopedic surgeons are often unaware of the different pre- and intraoperative ...

  19. AMPT-induced monoamine depletion in humans: evaluation of two alternative [123I]IBZM SPECT procedures

    International Nuclear Information System (INIS)

    Acute monoamine depletion paradigms using alpha-methyl-para-tyrosine (AMPT) combined with single photon emission computed tomography (SPECT) have been used successfully to evaluate disturbances in central dopaminergic neurotransmission. However, severe side effects due to relatively high doses (4,500 to 8,000 mg) of AMPT have been reasons for study withdrawal. Thus, we assessed the effectiveness and tolerability of two alternative procedures, using lower doses of AMPT. Six healthy subjects underwent three measurements of striatal dopamine D2 receptor (D2R)-binding potential (BPND) with SPECT and the selective radiolabeled D2R antagonist [123I]IBZM. All subjects were scanned in the absence of pharmacological intervention (baseline) and after two different depletion procedures. In the first depletion session, over 6 h, subjects were administered 1,500 mg of AMPT before scanning. In the second depletion session, over 25 h, subjects were administered 40 mg AMPT/kg body weight. We also administered the Subjective Well-being Under Neuroleptic Treatment Scale, a self-report instrument designed to measure the subjective experience of patients on neuroleptic medication. We found no change of mean D2R BPND after the first and short AMPT challenge compared to the baseline. However, we found a significant increase in striatal D2R BPND binding after the AMPT challenge adjusted for bodyweight compared to both other regimen. Although subjective well-being worsened after the prolonged AMPT challenge, no severe side effects were reported. Our results imply a low-dosage, suitable alternative to the common AMPT procedure. The probability of side effects and study withdrawal can be reduced by this procedure. (orig.)

  20. AMPT-induced monoamine depletion in humans: evaluation of two alternative [{sup 123}I]IBZM SPECT procedures

    Energy Technology Data Exchange (ETDEWEB)

    Boot, Erik [Academic Medical Centre (AMC), University of Amsterdam, Department of Psychiatry, Amsterdam (Netherlands); De Bruggen, Centre for People with Intellectual Disability, Zwammerdam (Netherlands); Booij, Jan [AMC, Department of Nuclear Medicine, Amsterdam (Netherlands); Hasler, Gregor [University Hospital, Department of Psychiatry, Zuerich (Switzerland); Zinkstok, Janneke R.; Haan, Lieuwe de; Linszen, Don H.; Amelsvoort, Therese A. van [Academic Medical Centre (AMC), University of Amsterdam, Department of Psychiatry, Amsterdam (Netherlands)

    2008-07-15

    Acute monoamine depletion paradigms using alpha-methyl-para-tyrosine (AMPT) combined with single photon emission computed tomography (SPECT) have been used successfully to evaluate disturbances in central dopaminergic neurotransmission. However, severe side effects due to relatively high doses (4,500 to 8,000 mg) of AMPT have been reasons for study withdrawal. Thus, we assessed the effectiveness and tolerability of two alternative procedures, using lower doses of AMPT. Six healthy subjects underwent three measurements of striatal dopamine D{sub 2} receptor (D{sub 2}R)-binding potential (BP{sub ND}) with SPECT and the selective radiolabeled D{sub 2}R antagonist [{sup 123}I]IBZM. All subjects were scanned in the absence of pharmacological intervention (baseline) and after two different depletion procedures. In the first depletion session, over 6 h, subjects were administered 1,500 mg of AMPT before scanning. In the second depletion session, over 25 h, subjects were administered 40 mg AMPT/kg body weight. We also administered the Subjective Well-being Under Neuroleptic Treatment Scale, a self-report instrument designed to measure the subjective experience of patients on neuroleptic medication. We found no change of mean D{sub 2}R BP{sub ND} after the first and short AMPT challenge compared to the baseline. However, we found a significant increase in striatal D{sub 2}R BP{sub ND} binding after the AMPT challenge adjusted for bodyweight compared to both other regimen. Although subjective well-being worsened after the prolonged AMPT challenge, no severe side effects were reported. Our results imply a low-dosage, suitable alternative to the common AMPT procedure. The probability of side effects and study withdrawal can be reduced by this procedure. (orig.)

  1. An Alternative and Rapid Method for the Extraction of Nucleic Acids from Ixodid Ticks by Potassium Acetate Procedure

    Directory of Open Access Journals (Sweden)

    Islay Rodríguez

    2014-08-01

    Full Text Available Four variants of the potassium acetate procedure for DNA extraction from ixodid ticks at different stage of their life cycles were evaluated and compared with phenol-chloroform and ammonium hydroxide methods. The most rapid and most efficient variant was validated in the DNA extraction procedure from the engorged ticks collected from bovine, canine as well as from house ticks for the screening of Borrelia burgdorferi sensu lato, Anaplasma spp. and Babesia spp. The ammonium hydroxide procedure was used for non-engorged ticks. All the variants were efficient and allowed obtaining PCR-quality material according to the specific amplification of 16S rRNA gene fragment of the original tick. DNA extracted from the ticks under the study was tested by multiplex PCR for the screening of tick-borne pathogens. Anaplasma spp. and Babesia spp. amplification products were obtained from 29/48 extracts. Ammonium hydroxide protocol was not efficient for two extracts. Detection of amplification products from the PCR indicated that DNA had been successfully extracted. The potassium acetate procedure could be an alternative, rapid, and reliable method for DNA extraction from the ixodid ticks, mainly for poorly-resourced laboratories.

  2. Alternative procedure for LR 115 chemical etching and alpha tracks counting

    International Nuclear Information System (INIS)

    An improved procedure for etching and analysis of alpha tracks induced in LR-115 detectors is proposed with the advantages of simplicity and its relatively low cost. A new type of detector holder was designed to etch and rinse efficiently up to 100 detectors. We develop a simple and reliable methodology with a semiautomatic track count using a Nikon digital camera coupled to a PC and employing software 'SCION' freely available on the Internet. Track images are binarized prior the application of software 'SCION' so that original track shapes are not distorted, space resolution is improved and track counting has low dependence on focus and illumination level. High discrimination for tracks is achieved when marks and rips perturb the detector surface. An image generator of nuclear tracks is included to study the effect of track overlapping effect on counting

  3. Alternative procedure for LR 115 chemical etching and alpha tracks counting

    Energy Technology Data Exchange (ETDEWEB)

    Arias, H. [Universidad Simon Bolivar, P.O. 89000, Caracas 1080-A (Venezuela); Palacios, D. [Universidad Simon Bolivar, P.O. 89000, Caracas 1080-A (Venezuela)]. E-mail: palacios@usb.ve; Sajo-Bohus, L. [Universidad Simon Bolivar, P.O. 89000, Caracas 1080-A (Venezuela); Viloria, T. [Universidad del Zulia, Maracaibo (Venezuela)

    2005-11-15

    An improved procedure for etching and analysis of alpha tracks induced in LR-115 detectors is proposed with the advantages of simplicity and its relatively low cost. A new type of detector holder was designed to etch and rinse efficiently up to 100 detectors. We develop a simple and reliable methodology with a semiautomatic track count using a Nikon digital camera coupled to a PC and employing software 'SCION' freely available on the Internet. Track images are binarized prior the application of software 'SCION' so that original track shapes are not distorted, space resolution is improved and track counting has low dependence on focus and illumination level. High discrimination for tracks is achieved when marks and rips perturb the detector surface. An image generator of nuclear tracks is included to study the effect of track overlapping effect on counting.

  4. Alternative Modal Basis Selection Procedures For Reduced-Order Nonlinear Random Response Simulation

    Science.gov (United States)

    Przekop, Adam; Guo, Xinyun; Rizi, Stephen A.

    2012-01-01

    Three procedures to guide selection of an efficient modal basis in a nonlinear random response analysis are examined. One method is based only on proper orthogonal decomposition, while the other two additionally involve smooth orthogonal decomposition. Acoustic random response problems are employed to assess the performance of the three modal basis selection approaches. A thermally post-buckled beam exhibiting snap-through behavior, a shallowly curved arch in the auto-parametric response regime and a plate structure are used as numerical test articles. The results of a computationally taxing full-order analysis in physical degrees of freedom are taken as the benchmark for comparison with the results from the three reduced-order analyses. For the cases considered, all three methods are shown to produce modal bases resulting in accurate and computationally efficient reduced-order nonlinear simulations.

  5. Monti’s procedure as an alternative technique in complex urethral distraction defect

    Directory of Open Access Journals (Sweden)

    Jalil Hosseini

    2010-06-01

    Full Text Available PURPOSE: Pelvic fracture urethral distraction defect is usually managed by the end to end anastomotic urethroplasty. Surgical repair of those patients with post-traumatic complex posterior urethral defects, who have undergone failed previous surgical treatments, remains one of the most challenging problems in urology. Appendix urinary diversion could be used in such cases. However, the appendix tissue is not always usable. We report our experience on management of patients with long urethral defect with history of one or more failed urethroplasties by Monti channel urinary diversion. MATERIALS AND METHODS: From 2001 to 2007, we evaluated data from 8 male patients aged 28 to 76 years (mean age 42.5 in whom the Monti technique was performed. All cases had history of posterior urethral defect with one or more failed procedures for urethral reconstruction including urethroplasty. A 2 to 2.5 cm segment of ileum, which had a suitable blood supply, was cut. After the re-anastomosis of the ileum, we closed the opened ileum transversely surrounding a 14-16 Fr urethral catheter using running Vicryl sutures. The newly built tube was used as an appendix during diversion. RESULTS: All patients performed catheterization through the conduit without difficulty and stomal stenosis. Mild stomal incontinence occurred in one patient in the supine position who became continent after adjustment of the catheterization intervals. There was no dehiscence, necrosis or perforation of the tube. CONCLUSION: Based on our data, Monti’s procedure seems to be a valuable technique in patients with very long complicated urethral defect who cannot be managed with routine urethroplastic techniques.

  6. Assessment of alternate procedures for the seismic analysis of multiply supported piping systems

    International Nuclear Information System (INIS)

    When response spectrum methods are used in the seismic analysis of piping systems the response due to inertial action, the dynamic response, and the response due to the time varying differential motions of the support points (the pseudo-static response) must be determined. In this study the adequacy and the degree of conservatism associated with the uniform response spectrum method, the center of mass response spectrum method and fourteen variants of the independent response spectrum method to compute the dynamic response and five different methods to compute the pseudo-static response were evaluated. For this purpose a sample of six piping systems, two of which were subjected to thirty-three earthquakes, were studied. For each system and seismic excitation a multiple independent support excitation time history analysis was developed and used to provide a best estimate of true response and to form the basis for comparison. A combination procedure to calculate the total responses is considered as well. Results are presented and compared to the corresponding responses evaluated using the current uniform response spectrum method and the center of mass response spectra approach. Based on the results, recommendations concerning the use of the methods were developed

  7. 16 CFR 1616.32 - Method for establishment and use of alternate laundering procedures under section 5(c)(4)(ii) of...

    Science.gov (United States)

    2010-01-01

    ...-14 (16 CFR 1616.5(c)(4)(ii)) requires that all fabrics and certain garments subject to the standard...(a) and 1 CFR part 51. (2) This rule provides the procedures to be followed by persons seeking... alternate laundering procedures under section 5(c)(4)(ii) of the standard. 1616.32 Section...

  8. 16 CFR 1615.32 - Method for establishment and use of alternate laundering procedures under section 4(g)(4)(ii) of...

    Science.gov (United States)

    2010-01-01

    ...-6X (16 CFR 1615.4(g)(4)(ii)) requires that all fabrics and certain garments subject to the standard...(a) and 1 CFR part 51. (2) This rule provides the procedures to be followed by persons seeking... alternate laundering procedures under section 4(g)(4)(ii) of the standard. 1615.32 Section...

  9. Treatment of PVC using an alternative low energy ion bombardment procedure

    Science.gov (United States)

    Rangel, Elidiane C.; dos Santos, Nazir M.; Bortoleto, José Roberto R.; Durrant, Steven F.; Schreiner, Wido H.; Honda, Roberto Y.; Rangel, Rita de Cássia C.; Cruz, Nilson C.

    2011-12-01

    In many applications, polymers have progressively substituted traditional materials such as ceramics, glasses, and metals. Nevertheless, the use of polymeric materials is still limited by their surface properties. Frequently, selective modifications are necessary to suit the surface to a given application. Amongst the most common treatments, plasma immersion ion implantation (PIII) has attracted the attention of many researchers owing to its versatility and practicality. This method, however, requires a power supply to provide high voltage (tens of kV) negative pulses, with a controlled duty cycle, width and frequency. Owing to this, the implementation of PIII on the industrial scale can become economically inviable. In this work, an alternative plasma treatment that enables low energy ion bombardment without the need of a high voltage pulse generator is presented. To evaluate the efficiency of the treatment of polymers, polyvinylchloride, PVC, specimens were exposed to 5 Pa argon plasmas for 3600 s, at excitation powers, P, of between 10 and 125 W. Through contact angle and atomic force microscopy data, the influence of P on the wettability, surface free energy and roughness of the samples was studied. Surface chemical composition was measured by X-ray photoelectron spectroscopy, XPS. To evaluate the effect of aging under atmospheric conditions, contact angle and XPS measurements were performed one and 1334 days after the treatment. The plasma potential and ion density around the driven electrode were determined from Langmuir probe measurements while the self-bias potential was derived with the aid of an oscilloscope. From these data it was possible to estimate the mean energy of ions bombarding the PVC surface. Chlorine, carbon and oxygen contamination were detected on the surface of the as-received PVC. Upon exposure to the plasma, the proportion of chlorine was observed to decrease while that of oxygen increased. Consequently, the wettability and surface energy

  10. Alternative procedure for the cold test for soybean seeds Procedimento alternativo para o teste de frio em semente de soja

    Directory of Open Access Journals (Sweden)

    Bruno Guilherme Torres Licursi Vieira

    2010-10-01

    Full Text Available The growing demand for high quality soybean [Glycine max (L. Merrill] seeds requires a precise seed quality control system from the seed industry. One way to accomplish this is by improving vigor testing. Cold test has been traditionally employed for corn seeds. However, it has also been used for other seed crops such as cotton (Gossypium spp., soybean (Glycine Max, dry bean (Phaseolus vulgaris and pea (Pisum sativum. This study was carried out with the objective of adjusting an alternative procedure for the cold test to determine soybean seed vigor. Six commercial soybean seed lots of the cultivar BRS 133 were used. The physiological potential of the seed lots was evaluated by germination on paper towel and sand box, seedling field emergence, tetrazolium, accelerated aging and electrical conductivity tests. Seed moisture content was also determined. The temperature used for the cold test procedures was 10ºC during five days. Four cold test procedures were evaluated: i plastic boxes with soil; ii rolled paper towel with soil; iii rolled paper towel without soil, and iv an alternative procedure, using rolled paper towel without soil under cold water. A completely randomized experimental design with eight replications was used and the means were compared by the Tukey test (p = 0.05. To verify the dependence between the alternative test and others single linear correlation was used. All cold test procedures had similar coefficients of variation (CV, highlighting that rolled paper towel with soil and the alternative procedure had the best performance, with an average of 94% and 93% normal seedlings and CV of 3.2% and 3.6%, respectively. The alternative procedure has satisfactory results for estimating soybean seed vigor, yielding consistent results compared to the traditional procedure.A crescente demanda por semente de soja [Glycine max (L. Merrill] de alta qualidade tem requerido da indústria de sementes um controle de qualidade mais preciso

  11. Academic Program Approval and Review Practices

    Directory of Open Access Journals (Sweden)

    Don G. Creamer

    1999-08-01

    Full Text Available This report outlines general and specific processes for both program approval and program review practices found in 50 states and eight foreign countries and regions.  Models that depict these procedures are defined and the strengths and weakness of each are discussed.  Alternatives to current practice by state agencies in the U.S. are described that might provide for greater decentralization of these practices while maintaining institutional accountability.

  12. Alternative Refractive Surgery Procedures

    Science.gov (United States)

    ... Uveitis Focus On Pediatric Ophthalmology Education Center Oculofacial Plastic Surgery Center Laser Surgery Education Center Redmond Ethics Center ... Uveitis Focus On Pediatric Ophthalmology Education Center Oculofacial Plastic Surgery Center Laser Surgery Education Center Redmond Ethics Center ...

  13. ProSeal laryngeal mask airway: An alternative to endotracheal intubation in paediatric patients for short duration surgical procedures

    Directory of Open Access Journals (Sweden)

    Jaya Lalwani

    2010-01-01

    Full Text Available The laryngeal mask airway (LMA is a supraglottic airway management device. The LMA is preferred for airway management in paediatric patients for short duration surgical procedures. The recently introduced ProSeal (PLMA, a modification of Classic LMA, has a gastric drainage tube placed lateral to main airway tube which allows the regurgitated gastric contents to bypass the glottis and prevents the pulmonary aspiration. This study was done to compare the efficacy of ProSeal LMA with an endotracheal tube in paediatric patients with respect to number of attempts for placement of devices, haemodynamic responses and perioperative respiratory complications. Sixty children, ASA I and II, weighing 10-20 kg between 2 and 8 years of age group of either sex undergoing elective ophthalmological and lower abdominal surgeries of 30-60 min duration, randomly divided into two groups of 30 patients each were studied. The number of attempts for endotracheal intubation was less than the placement of PLMA. Haemodynamic responses were significantly higher (P<0.05 after endotracheal intubation as compared to the placement of PLMA. There were no significant differences in mean SpO 2 (% and EtCO 2 levels recorded at different time intervals between the two groups. The incidence of post-operative respiratory complications cough and bronchospasm was higher after extubation than after removal of PLMA. The incidence of soft tissue trauma was noted to be higher for PLMA after its removal. There were no incidences of aspiration and hoarseness/sore throat in either group. It is concluded that ProSeal LMA can be safely considered as a suitable and effective alternative to endotracheal intubation in paediatric patients for short duration surgical procedures.

  14. 9 CFR 147.52 - Approved tests.

    Science.gov (United States)

    2010-01-01

    ... testing known negative samples, as determined by the official NPIP procedures found in this part. If... Approved Tests § 147.52 Approved tests. (a) The procedures for the bacteriological examination of poultry... kits) may be approved through the following procedure: (1) The sensitivity of the kit will be...

  15. The commercial and water-law approval procedure for mineral-oil transmission pipelines with integrated environmental impact assessment; Das gewerbe- und wasserrechtliche Zulassungsverfahren fuer Mineraloelfernleitungen mit integrierter Umweltvertraeglichkeitspruefung

    Energy Technology Data Exchange (ETDEWEB)

    Huber, J. [Bayerisches Staatsministerium fuer Arbeit und Sozialordnung, Familie, Frauen und Gesundheit, Muenchen (Germany)

    1995-03-01

    Mineral-oil transmission pipelines are an important component in the Federal Republic of Germany`s energy supply infrastructure. The pipeline system was largely planned and constructed in the 1960s. Approval permits were generally issued for a specified time, these times differing in the various federal states. The expiry of such a permit, significant modifications to a system, or the intended construction of a new pipeline all make it necessary to devote attention to the approval and permitting procedures incorporated in present-day legislation. The most important legal bases continue to be the permit issued in accordance with the Combustible Liquids Ordinance and approval in accordance with the Water Management Act. There are, however, other laws and regulations which are applicable to approval and have been enacted, in particular, to protect nature and the environment. Since the Act Regarding Environmental Impact Assesments (UVPG) came into effect on August 1, 1991, projects with an environmental significance may only be approved in the context of a procedure which includes an integrated Environmental Impact Assessment (EIA). This provision applies equally to approval for construction and operation of new systems and to the extension of permits for operation of existing mineral-oil transmission pipelines. This article describes the way the ``UVP`` affects the approval procedure. The author`s experience is used to illustrate the basic requirements for the environmental impact assessment; the organizational and chronological aspects of the approval procedure are also described. (orig.) [Deutsch] Mineraloelfernleitungen sind ein wichtiger Bestandteil der Energieversorgung in der Bundesrepublik Deutschland. Das Fernleitungsnetz wurde zum groessten Teil in den 60er Jahren projektiert und gebaut. Die Zulassungen wurden in der Regel befristet erteilt, wobei die Fristen in den Bundeslaendern unterschiedlich bemessen sind. Der Ablauf einer befristeten Zulassung, die

  16. 40 CFR Appendix A to Subpart Dddd... - Alternative Procedure To Determine Capture Efficiency From Enclosures Around Hot Presses in the...

    Science.gov (United States)

    2010-07-01

    ... (SF6) is used as a tracer gas (other tracer gases may be used if approved by the EPA Administrator... 13.0) also may be used. Specifically, gas chromatography with electron capture detection (GC/ECD) is..., “Verification of Gas Dilution Systems for Field Instrument Calibrations” (40 CFR part 51, appendix M)....

  17. 14 CFR Appendix J to Part 36 - Alternative Noise Certification Procedure for Helicopters Under Subpart H Having a Maximum...

    Science.gov (United States)

    2010-01-01

    ... Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from the... appendix must be determined by an FAA-approved method that is independent of normal flight instrumentation... reference under § 36.6 of this part, with regard to the specifications concerning microphone, amplifier,...

  18. Electronic Approval of Invoices (AEF)

    CERN Multimedia

    2004-01-01

    With a view to the simplification of administrative procedures, AS and FI Departments have completed the second phase of the new procedure for the electronic approval of invoices via the EDH application. The aim of this new procedure is to rationalise the invoice approval process, notably by eliminating paper copies from the approval circuit. This will simplify the processing of invoices and facilitate their timely settlement, while at the same time maintaining a high level of security. Phase II includes handling the electronic approval process of invoices whose amounts do not correspond exactly to those of the associated orders. In such cases, budgetary approval is required for the entire invoiced amount. Further information can be obtained at : http://ais.cern.ch/projs/AEF/help/F_help.htm Phase II of the procedure will be introduced gradually with effect from April 2004. Finance Department, Accounts Payable Section Tel: 72295 Organisation and Procedures Tel: 75885 Information Technologies Department,...

  19. 40 CFR Appendix A to Subpart Mmmm... - Alternative Capture Efficiency and Destruction Efficiency Measurement and Monitoring Procedures...

    Science.gov (United States)

    2010-07-01

    ... portion of the coating and the efficiency of the capture system. The organic carbon content of the control... 40 Protection of Environment 12 2010-07-01 2010-07-01 true Alternative Capture Efficiency and... and Products Pt. 63, Subpt. MMMM, App. A Appendix A to Subpart MMMM of Part 63—Alternative...

  20. A comparison of an alternative inventory control concept with the Navy's existing wholesale inventory control procedures for repairables

    OpenAIRE

    Kless, David R.

    1998-01-01

    The Director of Planning and Operation Research Department, Naval Inventory Control Point (NAVICP) Code M041, requested a study to compare the performance of two sets of inventory control procedures for managing high-cost repairable items. One of these sets is embedded in the Navy's existing wholesale inventory control system. The procedures of this set characterize a periodic review process, which calculates four decision variables in order to manage Navy inventories. These variables represe...

  1. Alternative procedure to shorten rectal barostat proecure for the assessment of rectal compliance and visceral perception: a feasibility study

    OpenAIRE

    Vanhoutvin, S.A.; Troost, F. J; Kilkens, T.O.; Lindsey, P. J.; Jonkers, D.M.; Venema, K.; Masclee, A.; Brummer, R J

    2012-01-01

    BACKGROUND: Barostat methodology is widely used for assessing visceral perception. Different barostat protocols are described with respect to the measurement of rectal compliance and visceral perception. The choice of protocols affects the duration, which is normally 60-90 min, and accuracy of the procedure. This study aimed to shorten the procedure by using the semi-random distension protocol for both compliance and visceral perception measurement and a correction based on rectal capacity (R...

  2. Energy efficiency procedures for agricultural machinery used in onion cultivation (Allium fistulosum) as an alternative to reduce carbon emissions under the clean development mechanism at Aquitania (Colombia)

    International Nuclear Information System (INIS)

    Climate change has both causes and consequences over agriculture. This paper focuses on the first element and presents scenarios for ASOLAGO -an onion cropper's association in Colombia with 250 members- to reduce their carbon footprint. It evaluates a case study at ''La Primavera'' farm using a methodology approved by the United Nations Framework Convention on Climate Change. Land preparation and crop irrigation were analyzed as stages in order to propose energy efficiency alternatives for both the farm and the association. They include field efficiency, fuel economy and energy efficiency from biofuels for the first stage as well as solar and wind energy supply for the second. A cost-benefit analysis to generate additional income selling additional power produced by the system to the National Grid was done

  3. Energy efficiency procedures for agricultural machinery used in onion cultivation (Allium fistulosum) as an alternative to reduce carbon emissions under the clean development mechanism at Aquitania (Colombia)

    Science.gov (United States)

    Ochoa, K.; Carrillo, S.; Gutierrez, L.

    2014-06-01

    Climate change has both causes and consequences over agriculture. This paper focuses on the first element and presents scenarios for ASOLAGO -an onion cropper's association in Colombia with 250 members- to reduce their carbon footprint. It evaluates a case study at "La Primavera" farm using a methodology approved by the United Nations Framework Convention on Climate Change. Land preparation and crop irrigation were analyzed as stages in order to propose energy efficiency alternatives for both the farm and the association. They include field efficiency, fuel economy and energy efficiency from biofuels for the first stage as well as solar and wind energy supply for the second. A cost-benefit analysis to generate additional income selling additional power produced by the system to the National Grid was done.

  4. 18 CFR 1304.7 - Conditions of approvals.

    Science.gov (United States)

    2010-04-01

    ... CONSTRUCTION IN THE TENNESSEE RIVER SYSTEM AND REGULATION OF STRUCTURES AND OTHER ALTERATIONS Procedures for Approval of Construction § 1304.7 Conditions of approvals. Approvals of applications shall contain...

  5. Court says 'no' to the practice of partial licensing subject to subsequent certain detail examination and approval within the nuclear installations licensing procedure. The current situation after the court decision in the Muelheim-Kaerlich case

    International Nuclear Information System (INIS)

    The final decision now taken by the Federal Administrative Court clarifies the judicial position vis-a-vis the practive of nuclear licensing authorities, to issue partial licences subject to subsequent examination and approval of certain details. (Decision 7 C 3/86 of the BVerwG, of September 9, 1988). The author discusses the court's decision in the Muelheim-Kaerlich case in the context of its impacts on the licensing practice, which developed some special features and procedures in the nuclear sector, and in regard to the legal status and scope of partial licences subject to subsequent detail examination. The article does not answer the question whether this court decision really will set an end to this practice in the nuclear licensing procedure. (RST)

  6. Electronic Approval of Invoices (AEF)

    CERN Multimedia

    2003-01-01

    With a view to the simplification of administrative procedures, AS and FI Divisions have drawn up a new procedure for the electronic approval of invoices via the EDH application. The aim of this new procedure is to rationalise the invoice approval process, notably by eliminating paper copies from the approval circuit. This will simplify the processing of invoices and facilitate their timely settlement, while at the same time maintaining a high level of security. This new procedure, in its current phase, will be gradually implemented from 1 November 2003 onwards. For clarification and further information, please see: http://ais.cern.ch/projs/AEF/help/help.htm . Finance Division, Accounts Payable Tel.: 7.22.95

  7. Approval plans issues and innovations

    CERN Document Server

    Katz, Linda S

    2013-01-01

    How can you, as an acquisition librarians, keep current on the output of hundreds of publishers? The answer, of course, is that you cannot. For over 30 years, approval plans have been used by librarians to acquire current titles, save staff time, and build core collections. Even today, these reasons seem appropriate, as libraries try to maintain up-to-date collections and control personnel and operating budgets. However, as shown in Approval Plans: Issues and Innovations, the use of approval plans is not so simple and straightforward; their use is subject to complex procedures and policies--an

  8. Preparation of biological samples for transmission X-ray microanalysis: a review of alternative procedures to the use of sectioned material

    International Nuclear Information System (INIS)

    Although transmission X-ray microanalysis of biological material has traditionally been carried out mainly on sectioned preparations, a number of alternative procedures exist. These are considered under three major headings - whole cell preparations, analysis of cell homogenates and biological fluids, and applications of the technique to microsamples of purified biochemicals. These three aspects provide a continuous range of investigative level - from the cellular to the molecular. The use of X-ray microanalysis with whole cell preparations is considered in reference to eukaryote (animal) cells and prokaryotes - where it has particular potential in environmental studies on bacteria. In the case of cell homogenates and biological fluids, the technique has been used mainly with microdroplets of animal material. The use of X-ray microanalysis with purified biochemicals is considered in relation to both particulate and non-particulate samples. In the latter category, the application of this technique for analysis of thin films of metalloprotein is particularly emphasised. It is concluded that wider use could be made of the range of preparative techniques available - both within a particular investigation, and in diverse fields of study. Transmission X-ray microanalysis has implications for environmental, physiological and molecular biology as well as cell biology

  9. A sentence completion procedure as an alternative to the Autobiographical Memory Test for assessing overgeneral memory in non-clinical populations.

    Science.gov (United States)

    Raes, Filip; Hermans, Dirk; Williams, J Mark G; Eelen, Paul

    2007-07-01

    Overgeneral memory (OGM) has been proposed as a vulnerability factor for depression (Williams et al., 2007) or depressive reactivity to stressful life-events (e.g., Gibbs & Rude, 2004). Traditionally, a cue word procedure known as the Autobiographical Memory Test (AMT; Williams & Broadbent, 1986) is used to assess OGM. Although frequently and validly used in clinical populations, there is evidence suggesting that the AMT is insufficiently sensitive to measure OGM in non-clinical groups. Study 1 evaluated the usefulness of a sentence completion method to assess OGM in non-clinical groups, as an alternative to the AMT. Participants were 197 students who completed the AMT, the Sentence Completion for Events from the Past Test (SCEPT), a depression measure, and visual analogue scales assessing ruminative thinking. Results showed that the mean proportion of overgeneral responses was markedly higher for the SCEPT than for the standard AMT. Also, overgeneral responding on the SCEPT was positively associated to depression scores and depressive rumination scores, whereas overgeneral responding on the AMT was not. Results suggest that the SCEPT, relative to the AMT, is a more sensitive instrument to measure OGM, at least in non-clinical populations. Study 2 further showed that this enhanced sensitivity is most likely due to the omission of the instruction to be specific rather than to the SCEPT's sentence completion format (as opposed to free recall to cue words). PMID:17613793

  10. Environmental procedures

    International Nuclear Information System (INIS)

    The European Bank has pledged in its Agreement to place environmental management at the forefront of its operations to promote sustainable economic development in central and eastern Europe. The Bank's environmental policy is set out in the document titled, Environmental Management: The Bank's Policy Approach. This document, Environmental Procedures, presents the procedures which the European Bank has adopted to implement this policy approach with respect to its operations. The environmental procedures aim to: ensure that throughout the project approval process, those in positions of responsibility for approving projects are aware of the environmental implications of the project, and can take these into account when making decisions; avoid potential liabilities that could undermine the success of a project for its sponsors and the Bank; ensure that environmental costs are estimated along with other costs and liabilities; and identify opportunities for environmental enhancement associated with projects. The review of environmental aspects of projects is conducted by many Bank staff members throughout the project's life. This document defines the responsibilities of the people and groups involved in implementing the environmental procedures. Annexes contain Environmental Management: The Bank's Policy Approach, examples of environmental documentation for the project file and other ancillary information

  11. Estimation procedure for engineering margin factors of WWER fuel cycles

    International Nuclear Information System (INIS)

    The paper informs the participants of the fact that working group H elaborated a draft document 'Estimation procedure for engineering margin factors of WWER fuel cycles'. The document represents recommendations and, if approved, shall be intended for estimation of engineering margin factors of WWER-440 and WWER-1000. To enable certain approaches, the document proposes a number of alternative solutions. The document will be distributed at the Symposium and may be discussed by the members to issue a final revision. (Authors)

  12. FFTF operations procedures preparation guide. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    1976-12-01

    The Guide is intended to provide guidelines for the initial preparation of FFTF Operating Procedures. The Procedures Preparation Guide was developed from the plan presented and approved in the FFTF Reactor Plant Procedures Plan, PC-1, Revision 3.

  13. 14 CFR 171.25 - Minimum requirements for approval.

    Science.gov (United States)

    2010-01-01

    ... (CONTINUED) NAVIGATIONAL FACILITIES NON-FEDERAL NAVIGATION FACILITIES Nondirectional Radio Beacon Facilities... met before the FAA will approve an IFR procedure for a non-Federal, nondirectional radio...

  14. DIGITALIZACIÓN 3D DEL RODETE DE UN COMPRESOR CENTRÍFUGO: UN PROCEDIMIENTO ALTERNATIVO 3D-DIGITIZING OF A CENTRIFUGAL COMPRESSOR'S IMPELLER: AN ALTERNATIVE PROCEDURE

    Directory of Open Access Journals (Sweden)

    Jairo Andrés Acosta Rojas

    2007-12-01

    characteristics which made it appropriate for the intended flow simulation, showing that the procedure used for this purpose constitutes a feasible alternative for the 3D digitizing of complex mechanical parts.

  15. Drugs Approved for Leukemia

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Leukemia This page lists cancer drugs approved by the ... not listed here. Drugs Approved for Acute Lymphoblastic Leukemia (ALL) Abitrexate (Methotrexate) Arranon (Nelarabine) Asparaginase Erwinia chrysanthemi ...

  16. 48 CFR 1406.304 - Approval of the justification.

    Science.gov (United States)

    2010-10-01

    ... justification. 1406.304 Section 1406.304 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Approval of the justification. A class justification shall be approved in accordance with bureau procedures. Copies of approved class justifications shall be promptly transmitted to PAM....

  17. Alternatives procedures for small farming sustainable management of parana pine Mecanismos alternativos para manejo sustentável de pinheiro-do-paraná na pequena propriedade rural

    Directory of Open Access Journals (Sweden)

    Jorge Zbigniew Mazuchowski

    2010-06-01

    Full Text Available

    After the expansion of agricultural frontier occurred in the southern brazilian region, which brought native forest substitution, new  management and alternatives practices were introduced in order to preserve and stimulate new plantings of the parana pine (Araucaria angustifolia . Alongside, in the last years, silviculturists have been promoting activities of forest development, in special with Pinus, Eucalyptus, Grevillea and bracatinga (Mimosa scabrella species to face wood depletion of native forest species. At the same time, new legal procedures also contributed to reduce new plantings of parana pine  because it tried to enforce simple preservation with high demands and tough inspection measures. Thus, representing 85 % of land structure in the State of Paraná, discouraged - small farmers were looking for to erradicate this species due to legal over regulation. Therefore, to  vercome this situation, mechanisms were offered to the silviculture management of Brazilian pine which were based in two central points tupgrading the existing laws and to incentive new plantations, specially in the areas set aside for environmental protection called of "Reserva Legal". In this way, the Extension Service (Emater tried to help this situation with the following prescription: technology diffusion; rewards to stimulate forest producers in the municipality; and formation of farmers groups to collect, select and to sell pine seeds.

    Em substituição às florestas nativas, pela abertura de fronteira agrícola, práticas agropecuárias alternativas foram introduzidas nas propriedades rurais com pinheiro-do-paraná (Araucaria angustifolia (Bert. O. Kunt. Porém, nos últimos anos, a silvicultura tem  promovido o desenvolvimento de atividades ligadas às madeiras de pínus, eucalipto, grevílea e bracatinga frente à exaustão de madeira oriunda de espécies florestais nativas, na geração de recursos no meio

  18. A Systematic Review of Consent Procedures, Participation Rates, and Main Findings of Health-Related Research in Alternative High Schools from 2010 to 2015

    Science.gov (United States)

    Johnson, Karen E.; Morris, Marian; Rew, Lynn; Simonton, Amanda J.

    2016-01-01

    There is a well-established link between educational attainment and health. Alternative high schools (AHSs) serve students who are at risk for school dropout. Health-related research conducted in AHSs has been sparse. Achieving high participation rates is critical to producing generalizable results and can be challenging in research with…

  19. ARE THE DECISIONS OF THE INTERNATIONAL BODIES IN ALTERNATIVE DISPUTE RESOLUTION (ADR BASED ON THE UNIFORM DISPUTE RESOLUTION POLICY (UDRP FOR DOMAIN NAMES SUBJECT OF THE COURT APPLICATION PROVIDED BY ARTICLE 364 ROMANIAN CIVIL PROCEDURE CODE?

    Directory of Open Access Journals (Sweden)

    Beatrice ONICA JARKA

    2009-11-01

    Full Text Available * This paper has been prepared within the research project „Standardization of Judicial Practice and Harmonization With the ECHR Jurisprudence, a Mandatory Condition to Enforce Justice. Legislative Proposal to Grant Aconsistent Judicial Practice” (ID-1094 financed by the Romanian Minister of Education, Research, Youth and Sports.The alternative dispute resolution (ADR for domain name disputes based on Uniform Dispute Resolution Policy (UDRP adopted by ICANN in 1999 provides for administrative proceedings. The decisions awarded in these proceedings shall be implemented directly by the domain names Registrars. The implementation is, according to paragraph 4 (k of the UDRP subject to stay if a Court proceeding in a competent jurisdiction is initiated in a 10 business days term from the date the domain name Registrar is informed about the Administrative Panel decision. The nature of the Court proceedings available under the local jurisdiction is not clear under UDRP, ICANN Rules for UDRP or the procedural rules adopted by the different UDRP procedure providers. This body of rules does not specify if the local proceedings subject the Administrative Panel decision to direct review or only provides for a procedural mean to stop the enforcement of such decision by obtaining a contrary Court decision. This amounts to a degree of uncertainty for the proceedings under the local law especially in countries where there is no legislation in connection to domain name, as it is Romania. The possibility to subject an Administrative Panel decision in an UDRP proceeding to the application to cancel an arbitration award provided by article 364 from the Romanian Civil Procedure Code is a tempting one. On the other side, the application provided by article 364 from the Romanian Civil Procedure Code may be founded only on limited legal grounds, some expressly provided by the said article being incompatible with the alternative dispute resolution (ADR for domain

  20. TMACS Test Procedure TP011: Panalarm Interface

    International Nuclear Information System (INIS)

    The TMACS Software Test Procedures translate the project's acceptance criteria into test steps. The TMACS Test Plan (WHC-SD-WM-TP-148) is fulfilled when all Test Cases are approved. This Test Procedure tests the TMACS Panalarm Interface functions

  1. A sentence completion procedure as an alternative to the Autobiographical Memory Test for assessing overgeneral memory in non-clinical populations

    OpenAIRE

    Raes, Filip; Hermans, Dirk; Williams, J. Mark G.; Eelen, Paul

    2007-01-01

    Overgeneral memory (OGM) has been proposed as a vulnerability factor for depression (Williams et al., 2007) or depressive reactivity to stressful life-events (e.g., Gibbs & Rude, 2004). Traditionally, a cue word procedure known as the Autobiographical Memory Test (AMT; Williams & Broadbent, 1986) is used to assess OGM. Although frequently and validly used in clinical populations, there is evidence suggesting that the AMT is insufficiently sensitive to measure OGM in non-clinical groups. Study...

  2. 14 CFR 183.53 - Procedures manual.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Procedures manual. 183.53 Section 183.53... manual. No ODA Letter of Designation may be issued before the Administrator approves an applicant's procedures manual. The approved manual must: (a) Be available to each member of the ODA Unit; (b) Include...

  3. A BAYESIAN ASSESSMENT OF P-VALUES FOR SIGNIFICANCE ESTIMATION OF POWER SPECTRA AND AN ALTERNATIVE PROCEDURE, WITH APPLICATION TO SOLAR NEUTRINO DATA

    International Nuclear Information System (INIS)

    The usual procedure for estimating the significance of a peak in a power spectrum is to calculate the probability of obtaining that value or a larger value by chance (known as the 'p-value'), on the assumption that the time series contains only noise-typically that the measurements are derived from random samplings of a Gaussian distribution. However, since the use of p-values in other contexts is known to be misleading, it seems prudent to examine the implications of using p-values for significance estimation of power spectra. We really need to know the probability that the time series is-or is not-compatible with the 'null hypothesis' that the measurements are derived from noise. This probability can be calculated by Bayesian analysis, but this requires one to specify and evaluate a second hypothesis that the time series does contain a contribution other than noise. We show that the requirement that the p-value should be identical to the probability that the null hypothesis is true leads to an unacceptable form for the likelihood function associated with this hypothesis. We claim that, for this reason, the p-value is not an acceptable method for significance estimation of a power spectrum. In order to obtain an acceptable significance estimate, it is necessary to explicitly consider a second hypothesis, and the key challenge is to identify an appropriate likelihood function for this hypothesis. We first propose four simple conditions that it seems reasonable to impose on this function. We then examine a general functional form for the function, and find the simplest form (which has one free parameter) that meets these conditions. We then define two different ways of combining information derived from two independent power estimates. One procedure is to calculate the post-probabilities of the null hypothesis, convert these to odds-values, and sum the log-odds. The second procedure is to combine the p-values using a procedure due to R.A. Fisher, and to calculate

  4. Post-Approval Studies

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CDRH Post-Approval Studies Program encompasses design, tracking, oversight, and review responsibilities for studies mandated as a condition of approval of a...

  5. Neubauer's plantlet method - an alternative procedure for evaluating the effectiveness of potassium based fertilizers in reducing radiocaesium from soil to plant

    International Nuclear Information System (INIS)

    Accidental releases of radiocaesium into the environment have necessitated the search for effective soil-based countermeasures to reduce its transfer along food-chains. As field experiments can be impractical and protracted to predict rapidly the effectiveness of chemical treatments of radioactive contaminated soils to reduce soil-to-plant transfer of radionuclides, laboratory experiments are a suitable alternative for rapid evaluation of the most appropriate countermeasure to apply under a range of different circumstances in the event of accidental radioactive contamination of agricultural lands. Taking into account these considerations our study focuses on the use of a laboratory experiment based on Neubauer's plantlet method to evaluate the effectiveness of potassic salt 30 % applied on two soil types (alluvial and brown-reddish forest type) contaminated with 137Cs for reducing uptake of the radionuclide to wheat plants grown-up on these soils. The experimental results evidence diminished values for 137Cs/K quotient in wheat plantlets grown-up on soils treated with potassic salt 30 %, compared to those registered for wheat plantlets grown-up on untreated soils. The diminished values of 137Cs/K quotient result from the reduced uptake of 137Cs to plantlets accompanied by the enhanced uptake of potassium. (author)

  6. A comunicação alternativa como procedimento de desenvolvimento de habilidades comunicativas Augmentative and alternative communication as a procedure for developing communication skills

    Directory of Open Access Journals (Sweden)

    Cândice Lima Moreschi

    2012-12-01

    Full Text Available O estudo teve como objetivo planejar, aplicar e avaliar os efeitos de um programa de intervenção sobre Comunicação Alternativa para o desenvolvimento de habilidades comunicativas de uma adolescente com deficiência intelectual. Participaram da pesquisa uma menina de 14 anos, com diagnóstico de deficiência intelectual e déficits na comunicação verbal, a mãe e a educadora da adolescente. Para verificar os efeitos da intervenção, foi utilizado o delineamento de sujeito único, do modelo AB. Nos resultados da avaliação pragmática, por meio do teste ABFW, ao comparamos o desempenho da participante antes e após a intervenção, verificou-se um aumento dos atos comunicativos e melhora significativa do conteúdo dialógico. Na Avaliação de Linguagem Receptiva e Expressiva, a participante obteve êxito em todos os itens da seção não verbal (pré e pós teste. Na seção verbal, após o processo de intervenção, a participante adquiriu a habilidade de imitar sons e iniciar diálogos. Na análise dos questionários aplicados aos pais e professora da adolescente, foi possível perceber alguns pontos de divergência quanto a habilidade em comunicar desejos e sentimentos e na execução de ordens dadas. Com o início do processo de intervenção, e com a introdução do Sistema de Comunicação Alternativa - PECS verificou-se que a participante passou a utilizar as figuras pictográficas como recurso comunicativo durante situações da vida diária. Embora a participante apresentasse comunicação verbal antes do início do processo de intervenção, essa comunicação não era eficiente durante as interações. Assim, a participante utilizou o Sistema de Comunicação como alternativa para aprimorar suas habilidades linguísticas, além de complementar sua comunicação oral.The study was designed to plan, implement and evaluate the effects of an Alternative Communication intervention program for developing the communication skills of a

  7. Waste Feed Delivery Environmental Permits and Approvals Plan

    International Nuclear Information System (INIS)

    This plan describes the environmental permits approvals, and other requirements that may affect establishment of a waste feed delivery system for the Hanford Site's River Protection Project. This plan identifies and screens environmental standards for potential applicability, outlines alternatives for satisfying applicable standards, and describes preferred permitting and approval approaches

  8. Waste Feed Delivery Environmental Permits and Approvals Plan

    Energy Technology Data Exchange (ETDEWEB)

    TOLLEFSON, K.S.

    2000-01-18

    This plan describes the environmental permits approvals, and other requirements that may affect establishment of a waste feed delivery system for the Hanford Site's River Protection Project. This plan identifies and screens environmental standards for potential applicability, outlines alternatives for satisfying applicable standards, and describes preferred permitting and approval approaches.

  9. Alternative security

    International Nuclear Information System (INIS)

    This book contains the following chapters: The Military and Alternative Security: New Missions for Stable Conventional Security; Technology and Alternative Security: A Cherished Myth Expires; Law and Alternative Security: Toward a Just World Peace; Politics and Alternative Security: Toward a More Democratic, Therefore More Peaceful, World; Economics and Alternative Security: Toward a Peacekeeping International Economy; Psychology and Alternative Security: Needs, Perceptions, and Misperceptions; Religion and Alternative Security: A Prophetic Vision; and Toward Post-Nuclear Global Security: An Overview

  10. 14 CFR 21.8 - Approval of articles.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Approval of articles. 21.8 Section 21.8 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.8 Approval of articles. If an article is required to...

  11. 19 CFR 115.63 - Application for approval.

    Science.gov (United States)

    2010-04-01

    ...) Particulars of construction; (ii) Dimensions; (iii) Construction materials; and (iv) Marks and numbers... TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures for Approval of Road Vehicles by Design Type § 115.63 Application for approval. Each...

  12. More New Medication Approvals.

    Science.gov (United States)

    Turkoski, Beatrice B

    2016-01-01

    In the past year, the Federal Drug Administration (FDA) approved many new drugs for treating a wide variety of patient health problems. In a previous article, examples of approvals for the early part of last year were addressed. In this article, selected new FDA approvals through January 2016 are discussed. Nurses who are knowledgeable and informed about these new drugs will be able to answer patients' questions, clarify misunderstandings, and reduce the potential for medication misadventures. PMID:27441881

  13. 沙门氏菌可替代方法实验室内验证程序研究%Study on the In-House Validation Procedure of Alternative Method for Salmonella spp.

    Institute of Scientific and Technical Information of China (English)

    马云; 王明鑑; 贾臻; 罗世芝; 王海霞; 郭君; 姚广红; 王茸; 贾俊涛

    2014-01-01

    为探索沙门氏菌可替代方法实验室内验证的具体程序,依据ISO 16140:2003/Amd 1:2011《食品和动物饲料微生物学-可替代方法的验证方案》,以赛默科技SureTect沙门氏菌实时PCR检测方法为例,对照参照方法进行了实验室内验证。所涉及的性能指标包括:①相对准确性、相对特异性和相对灵敏度;②相对检测限;③包含性和排他性。统计检验表明,该方法与参照方法在相对准确性、相对特异性和相对灵敏度方面无显著性差异,两种方法的相对检测限也无显著性差异。两种方法包含性和排他性检测结果基本一致。上述验证程序表明,检测方法的实验室内验证需遵循特定的程序,该验证程序可科学评价沙门氏菌可替代方法的性能。此次实验室内验证也可为类似的微生物检测方法验证提供参考。%In order to show the detailed procedure of in-house validation of the alternative methods for Salmonella spp., this study was conducted with SureTect real-time PCR Test for Salmonella spp. as an example and the reference method according to ISO 16140:2003/Amd:2011 Microbiology of food and animal feeding stuffs-Protocol for the validation of alternative method. The following performance indices were obtained:①The Relative Accuracy, Relative Specificity and Relative Sensitivity;②Relative Detection Level;③Inclusivity and Exclusivity. Statistical testings proved that there were no significant differences between the two methods for Relative Accuracy, Relative Specificity, Relative Sensitivity and Relative Detection Level respectively. As to the inclusivity and exclusivity, the results of the strains were almost congruent. The validation procedure mentioned above revealed that specific procedure should be implemented when in-house validation was launched and the procedure in this study could assess the performance of the alternative methods for Salmonella spp

  14. 43 CFR 45.74 - Has OMB approved the information collection provisions of this subpart?

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Has OMB approved the information... the Interior CONDITIONS AND PRESCRIPTIONS IN FERC HYDROPOWER LICENSES Alternatives Process § 45.74 Has... indicates OMB approval. OMB has reviewed the information collection in this rule and approved it under...

  15. 50 CFR 221.74 - Has OMB approved the information collection provisions of this subpart?

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Has OMB approved the information... PRESCRIPTIONS IN FERC HYDROPOWER LICENSES Alternatives Process § 221.74 Has OMB approved the information... it displays a currently valid OMB control number that indicates OMB approval. OMB has reviewed...

  16. 46 CFR 177.340 - Alternate design considerations.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Alternate design considerations. 177.340 Section 177.340... TONS) CONSTRUCTION AND ARRANGEMENT Hull Structure § 177.340 Alternate design considerations. When the... approved in accordance with §§ 177.300, 177.310 or 177.315, the structure may be approved by the...

  17. 24 CFR 248.223 - Alternative State strategy.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Alternative State strategy. 248.223... Preservation Act of 1987 § 248.223 Alternative State strategy. (a) The Commissioner may approve a State strategy providing for State approval of plans of action that involve termination of low...

  18. 14 CFR 21.441 - Procedure manual.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Procedure manual. 21.441 Section 21.441... manual. (a) No DAS may exercise any authority under this subpart unless it submits, and obtains approval of, a procedure manual containing— (1) The procedures for issuing STCs; and (2) The names,...

  19. Drugs Approved for Brain Tumors

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Brain Tumors This page lists cancer drugs approved by the ... that are not listed here. Drugs Approved for Brain Tumors Afinitor (Everolimus) Afinitor Disperz (Everolimus) Avastin (Bevacizumab) Becenum ( ...

  20. Drugs Approved for Hodgkin Lymphoma

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Hodgkin Lymphoma This page lists cancer drugs approved by the ... that are not listed here. Drugs Approved for Hodgkin Lymphoma Adcetris (Brentuximab Vedotin) Ambochlorin (Chlorambucil) Amboclorin (Chlorambucil) Becenum ( ...

  1. Drugs Approved for Prostate Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Prostate Cancer This page lists cancer drugs approved by the ... that are not listed here. Drugs Approved for Prostate Cancer Abiraterone Acetate Bicalutamide Cabazitaxel Casodex (Bicalutamide) Degarelix Docetaxel ...

  2. Drugs Approved for Pancreatic Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Pancreatic Cancer This page lists cancer drugs approved by the ... that are not listed here. Drugs Approved for Pancreatic Cancer Abraxane (Paclitaxel Albumin-stabilized Nanoparticle Formulation) Afinitor (Everolimus) ...

  3. 7 CFR 1751.104 - Obtaining RUS approval of a proposed Modernization Plan.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Obtaining RUS approval of a proposed Modernization... CRITERIA, AND PROCEDURES State Telecommunications Modernization Plan § 1751.104 Obtaining RUS approval of a proposed Modernization Plan. (a) To obtain RUS approval of a proposed Modernization Plan, the...

  4. 46 CFR 249.6 - Application procedures.

    Science.gov (United States)

    2010-10-01

    ... OPERATORS APPROVAL OF UNDERWRITERS FOR MARINE HULL INSURANCE § 249.6 Application procedures. (a) MARAD may grant specific approval for underwriters described in § 249.5(c) to participate in the writing of marine hull insurance on MARAD program vessels, only in advance of any actual placement. (b) Only...

  5. Update on Nonsurgical Lung Volume Reduction Procedures.

    Science.gov (United States)

    Neder, J Alberto; O'Donnell, Denis E

    2016-01-01

    There has been a surge of interest in endoscopic lung volume reduction (ELVR) strategies for advanced COPD. Valve implants, coil implants, biological LVR (BioLVR), bronchial thermal vapour ablation, and airway stents are used to induce lung deflation with the ultimate goal of improving respiratory mechanics and chronic dyspnea. Patients presenting with severe air trapping (e.g., inspiratory capacity/total lung capacity (TLC) 225% predicted) and thoracic hyperinflation (TLC > 150% predicted) have the greatest potential to derive benefit from ELVR procedures. Pre-LVRS or ELVR assessment should ideally include cardiological evaluation, high resolution CT scan, ventilation and perfusion scintigraphy, full pulmonary function tests, and cardiopulmonary exercise testing. ELVR procedures are currently available in selected Canadian research centers as part of ethically approved clinical trials. If a decision is made to offer an ELVR procedure, one-way valves are the first option in the presence of complete lobar exclusion and no significant collateral ventilation. When the fissure is not complete, when collateral ventilation is evident in heterogeneous emphysema or when emphysema is homogeneous, coil implants or BioLVR (in that order) are the next logical alternatives. PMID:27445557

  6. Update on Nonsurgical Lung Volume Reduction Procedures

    Directory of Open Access Journals (Sweden)

    J. Alberto Neder

    2016-01-01

    Full Text Available There has been a surge of interest in endoscopic lung volume reduction (ELVR strategies for advanced COPD. Valve implants, coil implants, biological LVR (BioLVR, bronchial thermal vapour ablation, and airway stents are used to induce lung deflation with the ultimate goal of improving respiratory mechanics and chronic dyspnea. Patients presenting with severe air trapping (e.g., inspiratory capacity/total lung capacity (TLC 225% predicted and thoracic hyperinflation (TLC > 150% predicted have the greatest potential to derive benefit from ELVR procedures. Pre-LVRS or ELVR assessment should ideally include cardiological evaluation, high resolution CT scan, ventilation and perfusion scintigraphy, full pulmonary function tests, and cardiopulmonary exercise testing. ELVR procedures are currently available in selected Canadian research centers as part of ethically approved clinical trials. If a decision is made to offer an ELVR procedure, one-way valves are the first option in the presence of complete lobar exclusion and no significant collateral ventilation. When the fissure is not complete, when collateral ventilation is evident in heterogeneous emphysema or when emphysema is homogeneous, coil implants or BioLVR (in that order are the next logical alternatives.

  7. Premarket Approvals (PMA)

    Data.gov (United States)

    U.S. Department of Health & Human Services — Premarket approval by FDA is the required process of scientific review to ensure the safety and effectiveness of all devices classified as Class III devices. An...

  8. Drugs Approved for Retinoblastoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for retinoblastoma. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  9. Drugs Approved for Melanoma

    Science.gov (United States)

    ... are not listed here. Drugs Approved for Melanoma Aldesleukin Cobimetinib Cotellic (Cobimetinib) Dabrafenib Dacarbazine DTIC-Dome (Dacarbazine) IL-2 (Aldesleukin) Imlygic (Talimogene Laherparepvec) Interleukin-2 (Aldesleukin) Intron A ( ...

  10. Drugs Approved for Neuroblastoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for neuroblastoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  11. FWS Approved Acquisition Boundaries

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data layer depicts the external boundaries of lands and waters that are approved for acquisition by the U.S. Fish and Wildlife Service (USFWS) in North...

  12. A Minimax Procedure for Electing Committees

    OpenAIRE

    Brams, Steven; Kilgour, Marc; Sanver, Remzi

    2006-01-01

    A new voting procedure for electing committees, called the minimax procedure, is described. Based on approval balloting, it chooses the committee that minimizes the maximum Hamming distance to voters' ballots, where these ballots are weighted by their proximity to other voters' ballots. This minimax outcome may be diametrically opposed to the outcome obtained by aggregating approval votes in the usual manner, which minimizes the sum of the Hamming distances and is called the minisum outcome. ...

  13. 7 CFR 1.674 - Has OMB approved the information collection provisions of §§ 1.670 through 1.673?

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Has OMB approved the information collection provisions... ADMINISTRATIVE REGULATIONS Conditions in FERC Hydropower Licenses Alternatives Process § 1.674 Has OMB approved... indicates OMB approval. OMB has reviewed the information collection in this rule and approved it under...

  14. Comparison of 3M Petrifilm Aerobic Count Plates to standard plating methodology for use with AOAC antimicrobial efficacy methods 955.14, 955.15, 964.02, and 966.04 as an alternative enumeration procedure: collaborative study.

    Science.gov (United States)

    Nelson, Maria T; LaBudde, Robert A; Tomasino, Stephen F; Pines, Rebecca M

    2013-01-01

    A multilaboratory study was conducted to determine the equivalence of the 3M Petrifilm Aerobic Count Plate and standard plating methodology for measuring viable bacteria and spores recovered from hard-surface carriers (stainless steel and porcelain), also known as "control carrier counts," used in AOAC antimicrobial efficacy test methods. Six laboratories participated in the study in which carriers inoculated with Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella enterica, and spores of Bacillus subtilis were evaluated using 3M Petrifilm Aerobic Count (AC) plates and standard plating side-by-side. The data were analyzed using a matched-pair t-test to determine the between-method effect with confidence intervals. For all test organisms pooled across all laboratories, the mean difference in log10 concentration between the standard plate count method and 3M Petrifilm AC Plates was -0.012, with a 95% confidence interval of (-0.090, +0.066), which was well within the -0.5, +0.5 interval established as the acceptance criterion. The between-carrier SD averaged 0.139; the between-replicate SD was 0.050. The carrier reproducibility, given that a single replicate per carrier is done, was estimated to be 0.148. Although differences were seen in the final concentrations of the test organisms among laboratories, there were no statistical differences between the enumeration methods. Based on the results from this study, 3M Petrifilm AC Plates are equivalent to standard plating methodology and can be used as an alternative procedure for the enumeration of test organisms used in AOAC Methods 955.14, 955.15, 964.02, and 966.04. PMID:24000742

  15. Project W-314 phase I environmental permits and approvals plan

    Energy Technology Data Exchange (ETDEWEB)

    TOLLEFSON, K.S.

    1999-02-24

    This document describes the range of environmental actions, including required permits and other agency approvals, for Project W-314 activities in the Hanford Site's Tank Waste Remediation System. This document outlines alternative approaches to satisfying applicable environmental standards, and describes selected strategies for acquiring permits and other approvals needed for waste feed delivery to proceed. This document also includes estimated costs and schedule to obtain the required permits and approvals based on the selected strategy. It also provides estimated costs for environmental support during design and construction based on the preliminary project schedule provided.

  16. Project W-314 phase I environmental permits and approvals plan

    International Nuclear Information System (INIS)

    This document describes the range of environmental actions, including required permits and other agency approvals, for Project W-314 activities in the Hanford Site's Tank Waste Remediation System. This document outlines alternative approaches to satisfying applicable environmental standards, and describes selected strategies for acquiring permits and other approvals needed for waste feed delivery to proceed. This document also includes estimated costs and schedule to obtain the required permits and approvals based on the selected strategy. It also provides estimated costs for environmental support during design and construction based on the preliminary project schedule provided

  17. Brodalumab: First Global Approval.

    Science.gov (United States)

    Greig, Sarah L

    2016-09-01

    Brodalumab (Lumicef(®)) is a human monoclonal immunoglobulin G antibody that is being developed by Kyowa Hakko Kirin in Japan, where it has been approved for the treatment of psoriasis vulgaris, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma. Brodalumab binds with high affinity to interleukin (IL)-17 receptor A, thereby inhibiting several pro-inflammatory cytokines from the IL-17 family. Regulatory applications for brodalumab in plaque psoriasis are also under review in the USA, EU and Canada. This article summarizes the milestones in the development of brodalumab leading to this first approval for the treatment of psoriasis. PMID:27577550

  18. For the approval process of GMOs: The Japanese case

    OpenAIRE

    Ebata, A.; Punt, M.J.; Wesseler, J.H.H.

    2013-01-01

    This article reviews the approval process of genetically modified organisms (GMOs) in Japan. The purpose of this review is to explain the Japanese safety approval procedures for food, feed, and imported GMOs and place it in an international context through a comparison with the United States and the European Union (EU). While the regulatory regime in the United States and EU is often discussed, little is understood about the Japanese regulations. However, Japan plays an important role in term...

  19. Venetoclax: First Global Approval.

    Science.gov (United States)

    Deeks, Emma D

    2016-06-01

    Venetoclax (Venclexta™) is an oral selective inhibitor of the prosurvival protein BCL-2 and therefore restores the apoptotic ability of malignant cells. The drug arose from research by Abbott Laboratories (now AbbVie) during a collaboration with Genentech and is being co-developed by AbbVie and Genentech/Roche primarily for the treatment of haematological malignancies. Venetoclax is approved in the USA for use as monotherapy in patients with chronic lymphocytic leukaemia (CLL) with the 17p deletion (as detected by an approved FDA test) who have received at least one prior therapy, and is awaiting approval for similar indications in the EU and Canada. Venetoclax is also in phase I-III development as combination therapy for CLL, phase I/II development as monotherapy and/or combination therapy for non-Hodgkin lymphomas (including diffuse large B-cell lymphoma, mantle cell lymphoma, follicular lymphoma) and acute myeloid leukaemia, and phase I development for multiple myeloma, systemic lupus erythematosus and breast cancer. This article summarizes the milestones in the development of venetoclax leading to this first approval for CLL. PMID:27260335

  20. FDA approved radiopharmaceuticals

    International Nuclear Information System (INIS)

    FDA is the abbreviation of American Food and Drug Administration. It s main job is assuring the safety and reliability of the food, cosmetics, medicines, medical devices and radiation emitting products such as microwave oven, the food and medicine for animals. Radiopharmaceuticals are also under its management. The basic information of FDA and FDA approved radiopharmaceuticals are introduced

  1. 23 CFR 655.605 - Project procedures.

    Science.gov (United States)

    2010-04-01

    ... FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS TRAFFIC OPERATIONS Traffic Control Devices on Federal-Aid and Other Streets and Highways § 655.605 Project procedures... shall follow procedures as established in 23 CFR part 630, subpart A, Federal-Aid Programs Approval...

  2. Quantization Procedures

    International Nuclear Information System (INIS)

    We present in this work a review of the conventional quantization procedure, the proposed by I.E. Segal and a new quantization procedure similar to this one for use in non linear problems. We apply this quantization procedures to different potentials and we obtain the appropriate equations of motion. It is shown that for the linear case the three procedures exposed are equivalent but for the non linear cases we obtain different equations of motion and different energy spectra. (Author) 16 refs

  3. Electronic Procedures for Medical Operations Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose an alternative to using Microsoft Word for representing medical procedures that will make the procedures easier to construct and maintain, particularly...

  4. Drugs Approved for Skin Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Skin Cancer This page lists cancer drugs approved by the Food and Drug Administration (FDA) for skin cancer, including drugs for basal cell carcinoma and melanoma. ...

  5. Alternative Treatments

    Science.gov (United States)

    ... Find your chapter: search by state Home > Alzheimer's Disease > Treatments > Alternative Treatments Overview What Is Dementia? What Is Alzheimer's? Younger/Early Onset Facts and Figures Know the 10 Signs Stages Inside the Brain: ...

  6. Cariprazine: First Global Approval.

    Science.gov (United States)

    McCormack, Paul L

    2015-11-01

    Cariprazine (Vraylar) is an oral atypical antipsychotic originated by Gedeon Richter. It is a potent dopamine D3 and D2 receptor partial agonist, which preferentially binds to the D3 receptor. Cariprazine also has partial agonist activity at serotonin 5-HT1A receptors. In September 2015, cariprazine received its first global approval in the USA for the treatment of schizophrenia and for the acute treatment of manic or mixed episodes associated with bipolar I disorder. It is also in development in a variety of countries for the treatment of schizophrenia with predominant negative symptoms (phase III), as adjunctive therapy for major depressive disorder (phase II/III) and for the treatment of bipolar depression (phase II). This article summarizes the milestones in the development of cariprazine leading to this first approval for schizophrenia and manic or mixed episodes associated with bipolar I disorder. PMID:26510944

  7. Fixed field alternating gradient

    OpenAIRE

    Machida, Shinji

    2013-01-01

    The concept of a fixed field alternating gradient (FFAG) accelerator was invented in the 1950s. Although many studies were carried out up to the late 1960s, there has been relatively little progress until recently, when it received widespread attention as a type of accelerator suitable for very fast acceleration and for generating high-power beams. In this paper, we describe the principles and design procedure of a FFAG accelerator.

  8. Dynamic alarm response procedures

    International Nuclear Information System (INIS)

    The Dynamic Alarm Response Procedure (DARP) system provides a robust, Web-based alternative to existing hard-copy alarm response procedures. This paperless system improves performance by eliminating time wasted looking up paper procedures by number, looking up plant process values and equipment and component status at graphical display or panels, and maintenance of the procedures. Because it is a Web-based system, it is platform independent. DARP's can be served from any Web server that supports CGI scripting, such as ApacheR, IISR, TclHTTPD, and others. DARP pages can be viewed in any Web browser that supports Javascript and Scalable Vector Graphics (SVG), such as NetscapeR, Microsoft Internet ExplorerR, Mozilla FirefoxR, OperaR, and others. (authors)

  9. Obiltoxaximab: First Global Approval.

    Science.gov (United States)

    Greig, Sarah L

    2016-05-01

    Obiltoxaximab (Anthim(®), ETI-204) is a monoclonal antibody that is being developed by Elusys Therapeutics and the US Department of Health and Human Services' Biomedical Advanced Research and Development Authority for the prevention and treatment of inhalational anthrax due to Bacillus anthracis. Obiltoxaximab has been designed to neutralize the free protective antigen of B. anthracis, thereby inhibiting the lethal effects of anthrax toxins. In March 2016, intravenous obiltoxaximab was approved in the USA for the treatment (in combination with appropriate antibacterial drugs) and prophylaxis of inhalational anthrax. Obiltoxaximab is being developed under the US FDA Animal Rule, in which marketing approval is based on its efficacy in relevant animal models and safety in phase I studies in healthy human volunteers. An intramuscular formulation of obiltoxaximab has also been evaluated in animal studies and a phase I study in healthy human volunteers. This article summarizes the milestones in the development of obiltoxaximab leading to this first approval for the treatment and prevention of inhalation anthrax. PMID:27085536

  10. Osimertinib: First Global Approval.

    Science.gov (United States)

    Greig, Sarah L

    2016-02-01

    Osimertinib (Tagrisso(™), AZD9291) is an oral, third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) that is being developed by AstraZeneca for the treatment of advanced non-small cell lung cancer (NSCLC). Osimertinib has been designed to target the EGFR T790M mutation that is often present in NSCLC patients with acquired EGFR TKI resistance, while sparing wild-type EGFR. In November 2015, the tablet formulation of osimertinib was granted accelerated approval in the USA for the treatment of patients with metastatic EGFR T790M mutation-positive NSCLC (as detected by an FDA-approved test) who have progressed on or after EGFR TKI therapy. Osimertinib has also been granted accelerated assessment status for this indication in the EU, and is in phase III development for first- and second-line and adjuvant treatment of advanced EGFR mutation-positive NSCLC in several countries. Phase I trials in patients with advanced solid tumours are also being conducted. This article summarizes the milestones in the development of osimertinib leading to this first approval for NSCLC. PMID:26729184

  11. Alternative Green Solvents Project

    Science.gov (United States)

    Maloney, Phillip R.

    2012-01-01

    Necessary for safe and proper functioning of equipment. Mainly halogenated solvents. Tetrachloride, Trichloroethylene (TCE), CFC-113. No longer used due to regulatory/safety concerns. Precision Cleaning at KSC: Small % of total parts. Used for liquid oxygen (LOX) systems. Dual solvent process. Vertrel MCA (decafluoropentane (DFP) and trons-dichloroethylene) HFE-7100. DFP has long term environmental concerns. Project Goals: a) Identify potential replacements. b) 22 wet chemical processes. c) 3 alternative processes. d) Develop test procedures. e) Contamination and cleaning. f) Analysis. g) Use results to recommend alternative processes. Conclusions: a) No alternative matched Vertrel in this study. b) No clear second place solvent. c) Hydrocarbons- easy; Fluorinated greases- difficult. d) Fluorinated component may be needed in replacement solvent. e) Process may need to make up for shortcoming of the solvent. f) Plasma and SCC02 warrant further testing.

  12. 76 FR 38741 - Tenth Meeting: RTCA Special Committee 221: Aircraft Secondary Barriers and Alternative Flight...

    Science.gov (United States)

    2011-07-01

    ... Alternative Flight Deck Security Procedures AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 221 meeting: Aircraft Secondary Barriers and Alternative Flight Deck... Special Committee 221: Aircraft Secondary Barriers and Alternative Flight Deck Security Procedures....

  13. 75 FR 9016 - Fifth Meeting: RTCA Special Committee 221: Aircraft Secondary Barriers and Alternative Flight...

    Science.gov (United States)

    2010-02-26

    ... Alternative Flight Deck Security Procedures AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 221 meeting: Aircraft Secondary Barriers and Alternative Flight Deck... Special Committee 221: Aircraft Secondary Barriers and Alternative Flight Deck Security Procedures....

  14. Site selection procedure for the final storage of radioactive waste?

    International Nuclear Information System (INIS)

    Since May, 22, 2002, Germany has had a licensed repository for radioactive waste, the former Konrad iron ore mine. The action brought against plans approval was dismissed by the Lower Saxony Higher Administrative Court at Lueneburg on March 8, 2006. The written reasons for the court ruling have been publicized in the meantime. The Lueneburg court recognized no appeal against its decision because it was unable to see any reasons for accepting an appeal on legal grounds. Among other factors, also the consideration played a role whether the plans approval decision under the Atomic Energy Act included the technical planning requirement to examine also alternative sites. Konrad could be commissioned if the competent minister so decided. However, in violation of the agreement achieved by nuclear power plant operators and the federal government in June 2001, Environment Minister Gabriel obviously does not want it to happen. Instead, he continues to pursue the plan announced by his predecessor in office several years earlier, i.e. to draft legislation about finding a 'best suited site' for a repository for radioactive waste. This raises the basic question whether legislation about site selection is necessary to solve the repository problem. The issue of a possible lack of legislation is discussed along with the legal situation of repositories determined in plans approval procedures. The ruling by the Lueneburg court about the Konrad repository is analyzed in detail. As far as the protective goals of the Atomic Energy Act are concerned, there is no indication of any lack of legislation which would have to be made up for by a procedural law about site selection. Existing laws offer sufficient assurance that only a site will chosen which meets the strict requirements under the Atomic Energy Act in material terms. (orig.)

  15. Making policy and procedure systems work effectively.

    Science.gov (United States)

    Virani, T

    1996-01-01

    Policy and procedure manuals can be cumbersome to keep current and updated. One approach to meet this challenge is by implementing a decentralized system to develop, review, revise and approve policies and procedures. Mechanisms to operationalize such a system involve sharing of responsibility and accountability of specified policies and procedures by various existing committees and development of coordinating systems and support mechanisms. Other key attributes of a decentralized system included collaboration and extensive communication strategies. PMID:8695607

  16. Behavioral implications of shortlisting procedures

    OpenAIRE

    Tyson, Christopher J.

    2012-01-01

    We consider two-stage "shortlisting procedures" in which the menu of alternatives is first pruned by some process or criterion and then a binary relation is maximized. Given a particular first-stage process, our main result supplies a necessary and sufficient condition for choice data to be consistent with a procedure in the designated class. This result applies to any class of procedures with a certain lattice structure, including the cases of "consideration filters," "satisficing with salie...

  17. 46 CFR 116.340 - Alternate design considerations.

    Science.gov (United States)

    2010-10-01

    ... ARRANGEMENT Hull Structure § 116.340 Alternate design considerations. The Commanding Officer, Marine Safety Center, may approve the structure of a vessel of novel design, unusual form, or special materials, which... principles that the vessel structure provides adequate safety and strength. An owner seeking approval of...

  18. 7 CFR 1735.94 - Final approval and closing procedure.

    Science.gov (United States)

    2010-01-01

    ..., permits, licenses, leases, title evidence, corporate proceedings, and contracts to be assigned to the... finance the acquisition, including the submission, in form and substance satisfactory to the...

  19. 46 CFR 160.077-6 - Approval procedures.

    Science.gov (United States)

    2010-10-01

    ... required in all three subparagraphs of § 159.005-5(a)(2) must be included in the application. (3) The application must also include the following: (i) The type of performance (i.e. Donned Type I, Type II or Type... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND...

  20. Cosmic alternatives?

    Science.gov (United States)

    Gregory, Ruth

    2009-04-01

    "Cosmologists are often in error but never in doubt." This pithy characterization by the Soviet physicist Lev Landau sums up the raison d'être of Facts and Speculations in Cosmology. Authors Jayant Narlikar and Geoffrey Burbidge are proponents of a "steady state" theory of cosmology, and they argue that the cosmological community has become fixated on a "Big Bang" dogma, suppressing alternative viewpoints. This book very much does what it says on the tin: it sets out what is known in cosmology, and puts forward the authors' point of view on an alternative to the Big Bang.

  1. Ethics Review Committee approval and informed consent: an analysis of biomedical publications originating from Sri Lanka

    OpenAIRE

    Siriwardhana Chesmal; Athukorale Manjula; Lekamwattage Manura; Hewege Suwin; Siribaddana Sisira; Sumathipala Athula; Murray Joanna; Prince Martin

    2008-01-01

    Abstract Background International guidelines on research have focused on protecting research participants. Ethical Research Committee (ERC) approval and informed consent are the cornerstones. Externally sponsored research requires approval through ethical review in both the host and the sponsoring country. This study aimed to determine to what extent ERC approval and informed consent procedures are documented in locally and internationally published human subject research carried out in Sri L...

  2. Surface Environmental Surveillance Procedures Manual

    Energy Technology Data Exchange (ETDEWEB)

    RW Hanf; TM Poston

    2000-09-20

    Environmental surveillance data are used in assessing the impact of current and past site operations on human health and the environment, demonstrating compliance with applicable local, state, and federal environmental regulations, and verifying the adequacy of containment and effluent controls. SESP sampling schedules are reviewed, revised, and published each calendar year in the Hanford Site Environmental Surveillance Master Sampling Schedule. Environmental samples are collected by SESP staff in accordance with the approved sample collection procedures documented in this manual.

  3. Growing Alternatives

    DEFF Research Database (Denmark)

    Bagger-Petersen, Mai Corlin

    2014-01-01

    From 2014, Anhui Province will pilot a reform of the residential land market in China, thus integrating rural Anhui in the national housing market. In contrast, artist and activist Ou Ning has proposed the Bishan time money currency, intending to establish an alternative economic circuit in Bishan...

  4. 75 FR 10013 - Agency Information Collection Activities: Request for Comments; Renewed Approval of Information...

    Science.gov (United States)

    2010-03-04

    ... in a right-of-way procedural (operations) manual the organization, policies and procedures of the...-date right-of-way procedural manual is set out in 23 CFR 710.201(c). The regulation allows States... Approval of Information Collection; State Right-of-Way Operations Manuals, OMB Control Number:...

  5. Necitumumab: First Global Approval.

    Science.gov (United States)

    Garnock-Jones, Karly P

    2016-02-01

    Eli Lilly is developing necitumumab (Portrazza™), an intravenously administered fully human IgG monoclonal antibody directed against the epidermal growth factor receptor (EGFR), which is expressed in a variety of solid tumours and has been implicated in promoting oncogenesis and tumour progression. Necitumumab is approved as a part of combination therapy (with gemcitabine and cisplatin) in the USA for the first-line treatment of metastatic squamous non-small cell lung cancer (NSCLC), and regulatory submissions have been made in the EU for this same indication. Necitumumab was derived from the proprietary phage display library of Dyax Corp, and originated with ImClone Systems, which was acquired by Eli Lilly in November 2008. Necitumumab was also under phase II development for colorectal cancer in Belgium and Spain; however, no recent development has been reported for this indication. This article summarizes the milestones in the development of necitumumab leading to this first approval for the first-line treatment of metastatic squamous NSCLC, in combination with gemcitabine and cisplatin. PMID:26729188

  6. 29 CFR 1956.80 - Description of the plan as initially approved.

    Science.gov (United States)

    2010-07-01

    ... with 29 CFR 1953.5. Any emergency temporary standards will be adopted within 30 days of Federal... procedures at 29 CFR 1905 within two years of plan approval. (d) Employee notice and discrimination... and the independence of the adjudicatory process within one year of plan approval. The Director...

  7. 14 CFR 91.1087 - Approval of aircraft simulators and other training devices.

    Science.gov (United States)

    2010-01-01

    ... included in the program manager's training program if approved by the Administrator. (b) Each aircraft... device may be used by more than one program manager. (d) In granting initial and final approval of... procedures listed in the program manager's curriculum under § 91.1079....

  8. 75 FR 58340 - Airworthiness Directives; Koito Industries, Ltd., Seats and Seating Systems Approved Under...

    Science.gov (United States)

    2010-09-24

    ... rule'' under the DOT Regulatory Policies and Procedures (44 FR 11034, February 26, 1979), and 3. Will..., Ltd., Seats and Seating Systems Approved Under Technical Standard Order (TSO) TSO-C39b, TSO-C39c, or..., Ltd., seats and seating systems approved under TSO-C39b, TSO-C39c, or TSO-C127a. This proposed...

  9. 77 FR 42306 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2012-07-18

    ... Human Health or the Environment AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY... approval according to the procedures prescribed in 5 CFR 1320.12. On October 25, 2011 (76 FR 66061), EPA... AGENCY Agency Information Collection Activities; Submission to OMB for Review and Approval;...

  10. 5 CFR 2471.1 - Request for Panel consideration; request for Panel approval of binding arbitration.

    Science.gov (United States)

    2010-01-01

    ... for Panel approval of binding arbitration. 2471.1 Section 2471.1 Administrative Personnel FEDERAL... consideration; request for Panel approval of binding arbitration. If voluntary arrangements, including the... procedure, which they have agreed to adopt, for binding arbitration of the negotiation impasse by filing...

  11. 78 FR 56648 - Notice of a Request for a Reinstatement of a Currently Approved Information Collection

    Science.gov (United States)

    2013-09-13

    ... Foreign Agricultural Service Notice of a Request for a Reinstatement of a Currently Approved Information... Service (FAS) intends to reinstate a currently approved information collection procedure for the Trade... at the mail address listed above between 8:00 a.m. and 4:30 p.m., Monday through Friday,...

  12. 7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

    Science.gov (United States)

    2010-01-01

    ... the application. (See 7 CFR part 1710, subpart F.) Prior to issuing the plans and specifications for... 7 Agriculture 11 2010-01-01 2010-01-01 false Requirements for RUS approval of plans and... DESIGN POLICIES AND PROCEDURES Electric System Design § 1724.54 Requirements for RUS approval of...

  13. Aviation Maintenance Technology. Course Content Guides. FAA Approved Curriculum.

    Science.gov (United States)

    Shrawder, Jack; And Others

    Course content guides are provided for the 30 courses in this aviation maintenance technology curriculum approved by the Federal Aviation Administration. Course titles are physics for technicians; aircraft information, regulations, and procedures; aircraft assembly; fundamentals of aircraft electronics; aircraft electrical components; aircraft…

  14. 12 CFR 303.62 - Transactions requiring prior approval.

    Science.gov (United States)

    2010-01-01

    ... merger transaction that consists of the acquisition by an out of state bank of a branch without... must provide certification of assumption of deposit liability to the FDIC in accordance with 12 CFR... FILING PROCEDURES Merger Transactions § 303.62 Transactions requiring prior approval. (a)...

  15. Whipple Procedure

    Science.gov (United States)

    ... Goggins Lab Sol Goldman Center Discussion Board The Whipple Procedure Also called a pancreaticoduodenectomy, which is generally ... operation was first described by .Dr. Alan O. Whipple of New York Memorial Hospital (now called Memorial ...

  16. 48 CFR 9.307 - Government administration procedures.

    Science.gov (United States)

    2010-10-01

    ... ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.307 Government administration procedures. (a) Before the contractor ships the first article, or the first article test report... requirements for testing and approval, or evaluation, as appropriate; (2) Call attention to the...

  17. Alternative 23

    OpenAIRE

    Jackson, Mark

    2014-01-01

    Alternative 23 is a curated exhibition of works by Steve Aylett, David Blandy & Daniel Locke, Let Me Feel Your Finger First, Laura Oldfield Ford, Plastique Fantastique and Henrik Schrat, including the first screening of Let Me Feel Your Finger First’s Postcolonial Capers. In 1985 DC Comics in the US had taken the commercial decision to unify the complex and contradictory character story arcs from its various strips such as Superman, Batman and Green Lantern. The resultant crossover series...

  18. 76 FR 61689 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2011-10-05

    ... and approval according to the procedures prescribed in 5 CFR 1320.12. On March 16, 2011 (76 FR 14390... (restricted entry interval); basic safety training (and voluntary training verification) and posting...

  19. 76 FR 58806 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2011-09-22

    ... approval according to the procedures prescribed in 5 CFR 1320.12. On November 3, 2010 (75 FR 67713), EPA... (PGP). EPA posted the final draft PGP on the Agency's Web site on April 1, 2011. Burden Statement:...

  20. 30 CFR 19.3 - Application procedures and requirements.

    Science.gov (United States)

    2010-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.3 Application procedures and requirements... accrediting organization; (2) Complete technical explanation of how the product complies with each...

  1. 18 CFR 1307.10 - Procedure for effecting compliance.

    Science.gov (United States)

    2010-04-01

    ... NONDISCRIMINATION WITH RESPECT TO HANDICAP § 1307.10 Procedure for effecting compliance. (a) General. If there... basis of handicap in violation of this part, and (3) the action has been approved by the TVA...

  2. Multinational design approval programme

    International Nuclear Information System (INIS)

    The licensing of new nuclear power facilities is likely to pose many challenges to national regulatory organizations. The majority of nuclear power plants to be built around the world in the next 15 years will likely be limited to a small number of relatively standardized designs, purchased from a limited number of multinational corporations. Such standardization creates an opportunity to leverage the resources and knowledge of the national regulatory authorities who will be tasked with the review of the new reactor power plant designs. The Nuclear Regulatory Commission has developed an innovative proposal for a multinational design approval programme (MDAP). This paper describes the stages of the MDAP and the benefits that could be derived from its implementation. (author)

  3. Drugs Approved for Lung Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Lung Cancer This page lists cancer drugs approved by the Food and Drug Administration (FDA) for lung cancer. The list includes generic and brand names. This page also lists common drug combinations used in lung ...

  4. Competent authority approval of package designs in the United Kingdom

    International Nuclear Information System (INIS)

    Type B packages and all packages containing fissile material, as well as special form materials, special arrangements and certain shipments, are required to be approved by the Competent Authority. In the United Kingdom, this function is carried out on behalf of the Secretary of State by the Radioactive Materials Transport Division of the Department of the Environment, Transport and the Regions (RMTD). Competent Authority approval is given only after a detailed assessment of the design by the specialist staff of RMTD. There are three facets to the assessment procedure, namely engineering, criticality and radiation protection, and quality assurance. The applicant is responsible for making the case for approval, but the assessment is facilitated if the Competent Authority is involved with the designer at an early stage in development and during the construction of the test prototype. Central to the approval process is the regulatory test program, which is designed and carried out by the applicant, but agreed and witnessed by representatives of RMTD. Following the test program, the applicant submit a formal application, supported by the Design Safety Report, which provides a full analysis of the design and the test results, including the behaviour of the package under normal and accident conditions of transport, the manufacturing and maintenance procedures, quality assurance and the emergency provisions for the operation of the package. RMTD produces a comprehensive Guide to Applications, which details the information required in all types of application for Competent Authority approval in the United Kingdom. (authors)

  5. Approval of raxibacumab for the treatment of inhalation anthrax under the US Food and Drug Administration Animal rule

    Directory of Open Access Journals (Sweden)

    Chia-Wei eTsai

    2015-12-01

    Full Text Available On December 14, 2012, the FDA approved raxibacumab, the first product developed under Project BioShield to achieve this milestone, and the first biologic product to be approved through the FDA animal efficacy rule (or Animal Rule. Raxibacumab is approved for the treatment of adult and pediatric patients with inhalational anthrax due to Bacillus anthracis in combination with appropriate antibiotic drugs and for prophylaxis of inhalational anthrax when alternative therapies are not available or are not appropriate. The approval of Raxibacumab illustrates many of the challenges that product developers may encounter when pursuing approval under the Animal Rule and highlights a number of important regulatory and policy issues.

  6. Energy alternatives

    International Nuclear Information System (INIS)

    Due to sharp rise in oil proces after the 1973 Arab-Israeli War, world attention has been focussed on the energy problem. At present the energy problem is limited to the cost and reliability of supply, even though there are enough supplies to go round. However, in the future the problem will be of availability, because in spite of the full exploitation of currently available conventional energy sources, the supply will fall short of demand which will always be increasing. Hence, there is need to develop alternate energy sources, including fast breeder reactors, fusion reactors and MHD. Economic and technical aspects of these energy are discussed. (M.G.B.)

  7. Alternative detente

    International Nuclear Information System (INIS)

    The influence of the Chernobyl accident on the disarmament and anti-nuclear movements is discussed. The accident directed attention towards the areas in common rather than the areas of disagreement. It also demonstrated the environmental impact of radioactivity, strengthening the ecological case of the anti-nuclear movement. The issues are discussed for the Western and Eastern bloc countries and the relationship between the two. Sections focus on the Eco-protest, Green politics and economics and on the politics of minority protest and the Green alternative. (U.K.)

  8. ARE THE DECISIONS OF THE INTERNATIONAL BODIES IN ALTERNATIVE DISPUTE RESOLUTION (ADR) BASED ON THE UNIFORM DISPUTE RESOLUTION POLICY (UDRP) FOR DOMAIN NAMES SUBJECT OF THE COURT APPLICATION PROVIDED BY ARTICLE 364 ROMANIAN CIVIL PROCEDURE CODE?

    OpenAIRE

    Beatrice ONICA JARKA

    2009-01-01

    * This paper has been prepared within the research project „Standardization of Judicial Practice and Harmonization With the ECHR Jurisprudence, a Mandatory Condition to Enforce Justice. Legislative Proposal to Grant Aconsistent Judicial Practice” (ID-1094) financed by the Romanian Minister of Education, Research, Youth and Sports.The alternative dispute resolution (ADR) for domain name disputes based on Uniform Dispute Resolution Policy (UDRP) adopted by ICANN in 1999 provides for administrat...

  9. 14 CFR 17.31 - Use of alternative dispute resolution.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Use of alternative dispute resolution. 17... PROCEDURAL RULES PROCEDURES FOR PROTESTS AND CONTRACTS DISPUTES Alternative Dispute Resolution § 17.31 Use of alternative dispute resolution. (a) The Office of Dispute Resolution for Acquisition shall encourage......

  10. The dilemma of approving antidotes.

    Science.gov (United States)

    Steffen, Christian

    2007-04-20

    Clinical trials with antidotes are difficult to perform for a variety of practical, ethical, and financial reasons. As acute poisoning is a rare event, the commercial interest in basic and clinical research is low. Poisoned patients are usually not available for normal clinical trial procedures and, if they are, they cannot give informed consent. This situation results in a dilemma: antidotes are essential drugs. A resolution of the Council of Europe requests to guarantee the optimal availability of antidotes and the improvement of their use. As comprehensive data on the efficacy of antidotes are often missing, a marketing authorisation under exceptional circumstances according to Article 14(8) of Regulation (EC) No. 276/2004, will often be the only way to get an approval, as: (1) the indications for which the product in question is intended are encountered so rarely that the applicant cannot reasonably be expected to provide comprehensive evidence ("orphan drug"), (2) in the present state of scientific knowledge, comprehensive information cannot be provided, or (3) it would be contrary to generally accepted principles of medical ethics to collect such data. Typically, data on antidotes are obtained from a patchwork of studies with animals, human tissue and a few observations from human poisoning corroborated with data from clinical observations and biochemistry. Generalisations from chemical and mechanistic similarities between groups of poisons are usual, but often lack scientific evidence. Current standards of good clinical practice can rarely be observed. Therefore, public funding and other financial support are necessary incentives to initiate trials in this important area. PMID:17207900

  11. Alternative crops

    International Nuclear Information System (INIS)

    Surplus cereal production in the EEC and decreasing product prices, mainly for cereals, has prompted considerable interest for new earnings in arable farming. The objective was to examine whether suggested new crops (fibre, oil, medicinal and alternative grains crops) could be considered as real alternatives. Whether a specific crop can compete economically with cereals and whether there is a market demand for the crop is analyzed. The described possibilities will result in ca. 50,000 hectares of new crops. It is expected that they would not immediately provide increased earnings, but in the long run expected price developments are more positive than for cereals. The area for new crops will not solve the current surplus cereal problem as the area used for new crops is only 3% of that used for cereals. Preconditions for many new crops is further research activities and development work as well as the establishment of processing units and organizational initiatives. Presumably, it is stated, there will then be a basis for a profitable production of new crops for some farmers. (AB) (47 refs.)

  12. 7 CFR 58.141 - Alternate quality control program.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by...

  13. 23 CFR 650.113 - Only practicable alternative finding.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Only practicable alternative finding. 650.113 Section... § 650.113 Only practicable alternative finding. (a) A proposed action which includes a significant encroachment shall not be approved unless the FHWA finds that the proposed significant encroachment is the...

  14. Drugs Approved for Stomach (Gastric) Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Stomach (Gastric) Cancer This page lists cancer drugs approved ... that are not listed here. Drugs Approved for Stomach (Gastric) Cancer Cyramza (Ramucirumab) Docetaxel Doxorubicin Hydrochloride 5- ...

  15. Drugs Approved for Non-Hodgkin Lymphoma

    Science.gov (United States)

    ... about Your Treatment Research Drugs Approved for Non-Hodgkin Lymphoma This page lists cancer drugs approved by the ... are not listed here. Drugs Approved for Non-Hodgkin Lymphoma Abitrexate (Methotrexate) Adcetris (Brentuximab Vedotin) Ambochlorin (Chlorambucil) Amboclorin ( ...

  16. Yttrium-90 Resin Microsphere Radioembolization Using an Antireflux Catheter: An Alternative to Traditional Coil Embolization for Nontarget Protection

    Energy Technology Data Exchange (ETDEWEB)

    Morshedi, Maud M., E-mail: maud.morshedi@my.rfums.org; Bauman, Michael, E-mail: mbauman@ucsd.edu; Rose, Steven C., E-mail: scrose@ucsd.edu; Kikolski, Steven G., E-mail: skikolski@gmail.com [University of California San Diego Health Sciences, Radiology Department, University of California San Diego Medical Center (United States)

    2015-04-15

    PurposeSerious complications can result from nontarget embolization during yttrium-90 (Y-90) transarterial radioembolization. Hepatoenteric artery coil embolization has been traditionally performed to prevent nontarget radioembolization. The U.S. Food and Drug Administration–approved Surefire Infusion System (SIS) catheter, designed to prevent reflux, is an alternative to coils. The hypothesis that quantifiable SIS procedural parameters are comparable to coil embolization was tested.MethodsFourteen patients aged 36–79 years with colorectal, neuroendocrine, hepatocellular, and other predominantly bilobar hepatic tumors who underwent resin microsphere Y-90 radioembolization using only the SIS catheter (n = 7) versus only detachable coils (n = 7) for nontarget protection were reviewed retrospectively. Procedure time, fluoroscopy time, contrast dose, radiation dose, and cost were evaluated.ResultsMultivariate analysis identified significant cohort differences in the procedural parameters evaluated (F(10, 3) = 10.39, p = 0.04). Between-group comparisons of the pretreatment planning procedure in the SIS catheter group compared to the coil embolization group demonstrated a significant reduction in procedure time (102.6 vs. 192.1 min, respectively, p = 0.0004), fluoroscopy time (14.3 vs. 49.7 min, respectively, p = 0.0016), and contrast material dose (mean dose of 174.3 vs. 265.0 mL, respectively, p = 0.0098). Procedural parameters were not significantly different between the two groups during subsequent dose delivery procedures. Overall cost of combined first-time radioembolization procedures was significantly less in the SIS group ($4252) compared to retrievable coil embolization ($11,123; p = 0.001).ConclusionThe SIS catheter results in a reduction in procedure time, fluoroscopy time, and contrast material dose and may be an attractive cost-effective alternative to detachable coil embolization for prevention of nontarget radioembolization.

  17. HARTMANN'S PROCEDURE – RESCUE OPERATIONS

    Directory of Open Access Journals (Sweden)

    A. Vasilescu

    2010-05-01

    Full Text Available Hartmann's procedure is the surgical resection of the superior rectum, rectosigmoid jonction and sigmoid colon with closure of the rectal stump and colostomy. It is is an alternative to Dixon procedure and it was used to treat complicated distal colon cancer (obstruction and peritonitis or diverticulitis (Hinchey stage III-IV. These days the indication to this procedure are limited to emergency surgery when immediate anastomosis is not possible, palliative surgery in colorectal cancer. During this procedure, the lesion is removed, the distal bowel closed intraperitoneally, and the proximal colon is brought to the stoma. It can be done by both open and laparoscopic approach. We describe a surgical technique and the problems that can occur. Hartmann's procedure has been reported to have a morbidity with rates ranging from 23% to 69% and a mortality rate ranging from 1% to 28%. Laparoscopic Hartmann’s procedure are technically feasible procedures with reasonable outcomes. Today Hartmann's procedure is still considered a valid alternative to localized or generalized peritonitis caused by perforation of the bowel secondary to the cancer or diverticulitis and in cases with viable but injured proximal bowel that precludes safe anastomosis.

  18. Energy alternatives

    International Nuclear Information System (INIS)

    English. A special committe of the Canadian House of Commons was established on 23 May 1980 to investigate the use of alternative energy sources such as 'gasohol', liquified coal, solar energy, methanol, wind and tidal power, biomass, and propane. In its final report, the committee envisions an energy system for Canada based on hydrogen and electricity, using solar and geothermal energy for low-grade heat. The committe was not able to say which method of generating electricty would dominate in the next century, although it recommends that fossil fuels should not be used. The fission process is not specifically discussed, but the outlook for fusion was investigated, and continued governmental support of fusion research is recommended. The report proposes some improvements in governmental energy organizations and programs

  19. 7 CFR 920.122 - Nomination procedures.

    Science.gov (United States)

    2010-01-01

    ... committee by a date specified by the committee and approved by an agent of the Secretary. Nomination forms... invalid nomination forms shall be notified of such by the committee. Within a reasonable time period, a... 7 Agriculture 8 2010-01-01 2010-01-01 false Nomination procedures. 920.122 Section...

  20. Radiochemical procedures

    International Nuclear Information System (INIS)

    The modern counting instrumentation has largely obviated the need for separation processes in the radiochemical analysis but problems in low-level radioactivity measurement, environmental-type analyses, and special situations caused in the last years a renaissance of the need for separation techniques. Most of the radiochemical procedures, based on the classic works of the Manhattan Project chemists of the 1940's, were published in the National Nuclear Energy Series (NNES). Improvements such as new solvent extraction and ion exchange separations have been added to these methods throughout the years. Recently the Los Alamos Group have reissued their collected Radiochemical Procedures containing a short summary and review of basic inorganic chemistry - 'Chemistry of the Elements on the Basis of Electronic Configuration'. (A.L.)

  1. Percutaneous duodenostomy - alternative route for enteral nutrition

    International Nuclear Information System (INIS)

    Percutaneous translumbar duodenostomy for enteral feeding was performed in one patient with nutritional difficulties. No complication was encountered. The procedure can be an alternative to percutaneous gastrostomy and jejunostomy for enteral feeding in special situations. (orig.)

  2. Drugs Approved for Bone Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for bone cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  3. Electronic Voucher Approval - Financial Management

    Data.gov (United States)

    US Agency for International Development — This process provides a workflow and eSignature capability which allows the CFO to router vouchers for review and electronic signature approval to COTRs in AIDW. It...

  4. Is It Really FDA Approved?

    Science.gov (United States)

    ... medical devices. These color additives (except coal-tar hair dyes) are subject by law to approval by the ... Examples of cosmetics are perfumes, makeup, moisturizers, shampoos, hair dyes, face and body cleansers, and shaving preparations. Cosmetic ...

  5. FDA-Approved HIV Medicines

    Science.gov (United States)

    ... and acronyms) Brand Name FDA Approval Date Nucleoside Reverse Transcriptase Inhibitors (NRTIs) NRTIs block reverse transcriptase, an enzyme HIV ... AZT, ZDV) Retrovir March 19, 1987 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) NNRTIs bind to and later alter reverse ...

  6. Drugs Approved for Vaginal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) to prevent vaginal cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  7. Drugs Approved for Penile Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for penile cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  8. Drugs Approved for Bladder Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for bladder cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  9. Drugs Approved for Malignant Mesothelioma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for malignant mesothelioma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  10. Drugs Approved for Kaposi Sarcoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Kaposi sarcoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  11. Drugs Approved for Vulvar Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for vulvar cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  12. Drugs Approved for Breast Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for breast cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  13. Drugs Approved for Wilms Tumor

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Wilms tumor and other childhood kidney cancers. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  14. Drugs Approved for Esophageal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for esophageal cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  15. Drugs Approved for Endometrial Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for endometrial cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  16. Drugs Approved for Liver Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for liver cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  17. PCB regulations and procedures for risk management including PCB clean-up policy and procedures

    International Nuclear Information System (INIS)

    This paper has two distinct but related parts. First, in Part 1, the PCB spill cleanup policy will be reviewed. Second, methods of disposal available to owners will be discussed. The pain associated with complying with spill cleanup requirements is causing many transformer owners to dispose of equipment as a method of eliminating PCB-related risks. Unfortunately, as the paper discusses in Part 2, some methods of legal disposal, which are allowed under the regulations, do not eliminate risks but may actually increase them. Once the rules are discussed, the paper offers an alternative that eliminates the long-term exposure risks caused by disposal of PCB-containing equipment. In particular, the paper presents a three-step solution to this problem that depends on the following: (1) specifying an appropriate method of disposal to completely destroy PCB's; (2) utilizing vendors who are EPA approved and inspected; and (3) reviewing thoroughly the control mechanisms and procedures used by vendors to prevent environmental exposures to PCB's and to ensure that the customers long-term liabilities are completely eliminated

  18. Intravenous infusion of ketamine-propofol can be an alternative to intravenous infusion of fentanyl-propofol for deep sedation and analgesia in paediatric patients undergoing emergency short surgical procedures

    Directory of Open Access Journals (Sweden)

    Samit Kumar Khutia

    2012-01-01

    Full Text Available Background: Paediatric patients often present with different painful conditions that require immediate surgical interventions. Despite a plethora of articles on the ketamine-propofol combination, comprehensive evidence regarding the suitable sedoanalgesia regime is lacking due to heterogeneity in study designs. Methods: This prospective, randomized, double-blind, active-controlled trial was conducted in 100 children, of age 3-14 years, American Society of Anesthesiologist physical status IE-IIE, posted for emergency short surgical procedures. Patients were randomly allocated to receive either 2 mL of normal saline (pre-induction plus calculated volume of drug from the 11 mL of ketamine-propofol solution for induction (group PK, n=50 or fentanyl 1.5 μg/kg diluted to 2 mL with normal saline (pre-induction plus calculated volume of drug from the 11 mL of propofol solution for induction (group PF, n=50. In both the groups, the initial bolus propofol 1 mg/kg i.v. (assuming the syringes contained only propofol, for simplicity was followed by adjusted infusion to achieve a Ramsay Sedation Scale score of six. Mean arterial pressure (MAP was the primary outcome measurement. Results: Data from 48 patients in group PK and 44 patients in group PF were available for analysis. Hypotension was found in seven patients (14.6% in group PK compared with 17 (38.6% patients in group PF (P=0.009. Intraoperative MAP was significantly lower in group PF than group PK when compared with baseline. Conclusion: The combination of low-dose ketamine and propofol is more effective and a safer sedoanalgesia regimen than the propofol-fentanyl combination in paediatric emergency short surgical procedures in terms of haemodynamic stability and lesser incidence of apnoea.

  19. ALTERNATIVE DISPUTE RESOLUTION

    Directory of Open Access Journals (Sweden)

    Mihaela Irina IONESCU

    2015-12-01

    Full Text Available Alternative dispute resolution (ADR includes dispute resolution processes and techniques that act as a means for disagreeing parties to come to an agreement short of litigation. It is a collective term for the ways that parties can settle disputes, with (or without the help of a third party.Despite historic resistance to ADR by many popular parties and their advocates, ADR has gained widespread acceptance among both the general public and the legal profession in recent years. In fact, some courts now require some parties to resort to ADR of some type, before permitting the parties' cases to be tried. The rising popularity of ADR can be explained by the increasing caseload of traditional courts, the perception that ADR imposes fewer costs than litigation, a preference for confidentiality, and the desire of some parties to have greater control over the selection of the individual or individuals who will decide their dispute.Directive 2013/11/EU of the European Parliament and of the Council on alternative dispute resolution for consumer disputes and amending Regulation (EC No 2006/2004 and Directive 2009/22/EC (hereinafter „Directive 2013/11/EU” aims to ensure a high level of consumer protection and the proper functioning of the internal market by ensuring that complaints against traders can be submitted by consumers on a voluntary basis, to entities of alternative disputes which are independent, impartial, transparent, effective, simple,quick and fair.Directive 2013/11/EU establishes harmonized quality requirements for entities applying alternative dispute resolution procedure (hereinafter "ADR entity" to provide the same protection and the same rights of consumers in all Member States.Besides this, the present study is trying to present broadly how are all this trasposed in the romanian legislation.

  20. Alternative Splice in Alternative Lice.

    Science.gov (United States)

    Tovar-Corona, Jaime M; Castillo-Morales, Atahualpa; Chen, Lu; Olds, Brett P; Clark, John M; Reynolds, Stuart E; Pittendrigh, Barry R; Feil, Edward J; Urrutia, Araxi O

    2015-10-01

    Genomic and transcriptomics analyses have revealed human head and body lice to be almost genetically identical; although con-specific, they nevertheless occupy distinct ecological niches and have differing feeding patterns. Most importantly, while head lice are not known to be vector competent, body lice can transmit three serious bacterial diseases; epidemictyphus, trench fever, and relapsing fever. In order to gain insights into the molecular bases for these differences, we analyzed alternative splicing (AS) using next-generation sequencing data for one strain of head lice and one strain of body lice. We identified a total of 3,598 AS events which were head or body lice specific. Exon skipping AS events were overrepresented among both head and body lice, whereas intron retention events were underrepresented in both. However, both the enrichment of exon skipping and the underrepresentation of intron retention are significantly stronger in body lice compared with head lice. Genes containing body louse-specific AS events were found to be significantly enriched for functions associated with development of the nervous system, salivary gland, trachea, and ovarian follicle cells, as well as regulation of transcription. In contrast, no functional categories were overrepresented among genes with head louse-specific AS events. Together, our results constitute the first evidence for transcript pool differences in head and body lice, providing insights into molecular adaptations that enabled human lice to adapt to clothing, and representing a powerful illustration of the pivotal role AS can play in functional adaptation. PMID:26169943

  1. 28 CFR 2.41 - Travel approval.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Travel approval. 2.41 Section 2.41..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.41 Travel approval. (a) The probation officer may approve travel outside the district without approval of...

  2. 76 FR 46352 - Approval of Noise Compatibility Program for San Diego International, San Diego, CA

    Science.gov (United States)

    2011-08-02

    ... approved. No program elements relating to new or revised flight procedures for noise abatement were... actions for noise abatement, noise mitigation, land use planning and program management on and off the... environmental analysis. Any new procedures proposed for noise abatement at SAN may not be implemented prior to...

  3. The Wkb Approximation through a Factorization Procedure

    International Nuclear Information System (INIS)

    We develop an alternative approach to the Wkb approximation through a factorization procedure for the one -dimensional time independent Schrodinger equation. The method yields the expected Wkb results for slowly varying potentials.

  4. Looking for an Alternative.

    Science.gov (United States)

    Kennedy, Jack

    1999-01-01

    Argues that high school newspapers might do well to create stronger ties with alternative weeklies. Discusses issues of niche marketing, alternative content, and alternative presentation. Notes that high school papers could learn a lot from alternative newspapers. (SR)

  5. 7 CFR 1753.29 - Force account procedures.

    Science.gov (United States)

    2010-01-01

    ... major construction item. (4) An estimate of the material and labor and other costs for any construction... 7 Agriculture 11 2010-01-01 2010-01-01 false Force account procedures. 1753.29 Section 1753.29... Force account procedures. (a) The borrower must obtain RUS approval of the force account method...

  6. 48 CFR 432.003 - Simplified acquisition procedures financing.

    Science.gov (United States)

    2010-10-01

    ... procedures financing. 432.003 Section 432.003 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING 432.003 Simplified acquisition procedures financing. (a) The chief of the contracting office may approve contract financing on a contract to...

  7. Terapia celular associada à revascularização transmiocárdica laser como proposta no tratamento da angina refratária Cell therapy plus transmyocardial laser revascularization: a proposed alternative procedure for refractory angina

    Directory of Open Access Journals (Sweden)

    Luís Alberto Oliveira Dallan

    2008-03-01

    Full Text Available OBJETIVO: É descrita uma proposição cirúrgica para o tratamento de pacientes com doença arterial coronária (DAC terminal, não mais passíveis de revascularização miocárdica convencional. Constitui-se na revascularização transmiocárdica com raios laser (RTML, associada ao emprego de células progenitoras hematopoiéticas autólogas (CPH. MÉTODOS: Nove pacientes (oito homens, 65±5 anos, com as características supracitadas foram submetidos ao procedimento combinado. Além da avaliação clínica, o protocolo incluiu o estudo da perfusão miocárdica através da ressonância cardíaca (RMC sob estresse farmacológico, antes e seis meses após a intervenção cirúrgica. Procedeuse à RMTL através de minitoracotomia esquerda e utilização de laser de CO2, com média de 11±3 tiros por paciente. As CPH foram obtidas por punção medular, seguindo-se sua injeção direta (1,9±0,3x10(8 células/paciente em múltiplas áreas do miocárdio isquêmico. RESULTADOS: Não ocorreram óbitos ou complicações imediatas decorrentes dos procedimentos. Um paciente faleceu no segundo ano de pós-operatório, de causa não cardíaca (choque séptico. O seguimento clínico pós-operatório desses pacientes revelou redução significativa da classe funcional de angina de 3,7±0,2 para 1,3±0,2 (pOBJECTIVE: We tested the hypothesis that TMLR combined with intramyocardial injection of BMC is safe, and may help increase the functional capacity of patient with refractory angina. METHODS: Nine patients (eight men, 65±5 years old, with refractory angina for multivessel disease and previous myocardial revascularization procedures (CABG/PCI, not candidates for another procedure due to the extension of the disease were enrolled. TMLR (11±3 laser drills was performed via a limited thoracotomy using a CO2 Heart Laser System. BMC were obtained immediately prior to surgery, and the lymphomonocytic fraction separated by density gradient centrifugation. During

  8. On the isolation of elemental carbon for micro-molar 14C accelerator mass spectrometry; evaluation of alternative isolation procedures, and accuracy assurance using a hybrid isotopic particulate carbon reference material

    Directory of Open Access Journals (Sweden)

    L. A. Currie

    2005-05-01

    Full Text Available The primary objective of the research reported here has been the development of an hybrid reference material (RM to serve as a test of accuracy for elemental carbon (EC isotopic (14C speciation measurements. Such measurements are critically important for the quantitative apportionment of fossil and biomass sources of ''soot'' (EC, the tracer of fire that has profound effects on health, atmospheric visibility, and climate. Previous studies of 14C-EC measurement quality, carried out with NIST SRM 1649a (Urban Dust, showed a range of results, but since the ''truth'' was not known for this natural matrix RM, one had to rely on isotopic-chemical consistency evidence (14C in PAH, EC of measurement validity (Currie et al., 2002. Components of the new Hybrid RM (DiesApple, however, have known 14C and EC composition, and they are nearly orthogonal (isotopically and chemically. NIST SRM 2975 (Forklift Diesel Soot has little or no 14C, and its major compositional component is EC. SRM 1515 (Apple Leaves has the 14C content of biomass-C, and it has little or no EC. Thus, the hybrid RM can serve as an absolute isotopic test for the absence of EC-mimicking pyrolysis-C from SRM 1515 in the EC isolate of the hybrid RM, together with testing for conservation of its dominant soot fraction through the isolation procedure.

  9. Full load rejection procedure for Point Lepreau GS

    International Nuclear Information System (INIS)

    In 1999 WANO issued Significant Operating Event Report 99-01 recommending that the industry verify whether or not currently approved procedures were adequate for a loss or degradation of the electrical grid. A detailed review identified that the procedures available at the time were not adequate to respond effectively to such a disturbance. Operations personnel reviewed operating expectations and the expected plant response to a Loss of Grid and updated the Operating Manual to cover 'Full Load Rejection'. Operations used the simulators to validate the procedure and train crews and Licensed staff. The revised documentation was approved and implemented. (author)

  10. 21 CFR 900.18 - Alternative requirements for § 900.12 quality standards.

    Science.gov (United States)

    2010-04-01

    ... may approve an alternative to a quality standard under § 900.12, when the agency determines that: (1) The proposed alternative standard will be at least as effective in assuring quality mammography as the... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Alternative requirements for § 900.12...

  11. 75 FR 52591 - Seventh Meeting: RTCA Special Committee 221: Aircraft Secondary Barriers and Alternative Flight...

    Science.gov (United States)

    2010-08-26

    ... and Alternative Flight Deck Security Procedures AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 221 meeting: Aircraft Secondary Barriers and Alternative Flight... RTCA Special Committee 221: Aircraft Secondary Barriers and Alternative Flight Deck Security...

  12. 76 FR 75809 - Prior Label Approval System: Generic Label Approval

    Science.gov (United States)

    2011-12-05

    ... the type of packaging material on which the label is printed; n. Brand name changes, provided that... poultry products will take effect January 1, 2012 (75 FR 82148, Dec. 29, 2010). These mandatory features..., location, and indication of final color. To obtain sketch label approval, domestic meat and...

  13. Program change control procedure: Revision 1

    International Nuclear Information System (INIS)

    The Program Change Control Procedure is part of the Office of Civilian Radioactive Waste Management (OCRWM) Program Management System (PMS), as described in the PMS Manual. The Program Change Control Board (PCCB) may develop additional procedures, as necessary, to supplement this procedure. The PMS Manual identifies ''managing for quality'' as a major goal in the management of OCRWM activities to achieve and maintain a high level of quality in all program activities. The procedures established in this document are intended to ensure that the program-level controlled documents are maintained and updated consistent with that goal. Documents subject to change control procedures are referred to as controlled documents. Controlled documents ensure that all program participants are working according to the same ground rules. Change control management ensures that all changes made to any controlled document issued by the program are assessed and approved by a process that adequately considers overall program impacts

  14. Alternatives to animal experimentation in basic research.

    Science.gov (United States)

    Gruber, Franz P; Hartung, Thomas

    2004-01-01

    In contrast to animal testing required by law to guarantee minimum safety standards for the licensing of drugs and chemicals, there are no regulations in basic research forcing scientists to perform animal tests. By (usually) free choice, questions are posed and hypotheses are examined which, in many cases, can only be answered by means of animal tests. Just as easily, different questions could be asked or different hypotheses could be examined which do not require animal tests. The only criterion for the choice of a topic is its relevance which cannot necessarily be judged in the short-term. Thus, it is up to the individual scientist to judge what is worth studying and therefore worth animal consumption. The educated mind will consider ethical aspects of this choice. However, on the other hand, this decision is largely influenced by questions of efficacy or (in a negative sense) by the obstacles posed to an animal consuming approach. Here, peer review and general attitude will strongly influence the methodology chosen. Availability and awareness of adequate in vitro techniques represent the prerequisites for the use of alternative methods. The least one can do in basic research is to avoid tests which cause severe suffering to animals, as is required in Switzerland and other European countries by binding ethical principles and guidelines. The increasing standard of approval and control procedures has improved the situation over the years. There are many examples of successful alternative methods in basic research. But, the application of such methods is in most cases limited to the laboratories in which they were developed, calling for technology transfer. Exceptions are procedures that are used worldwide, like the production of monoclonal antibodies, which instead of using the ascites mouse can also be performed in vitro with some good will. In these cases, commercialisation of the techniques has aided their spread within the scientific community. Sadly, many

  15. Drugs Approved for Multiple Myeloma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for multiple myeloma and other plasma cell neoplasms. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  16. Drugs Approved for Cervical Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for cervical cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  17. Drugs Approved for Testicular Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for testicular cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  18. Alkylbenzene Project in Xinjiang Approved

    Institute of Scientific and Technical Information of China (English)

    Zhou Weiyong

    1996-01-01

    @@ The feasibility study on alkylbenzene project in Dushanzi, Xinjiang Uygur Autonomous Region, submitted jointly by the government of Xinjiang UygurAutonomous Region and China National Petroleum Corporation (CNPC), has been approved by State Council recently,after pass appraisa l by China International Engineering Consulting Corporation entrusted by State Planning Committee.

  19. Drugs Approved for Myeloproliferative Neoplasms

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for myeloproliferative neoplasms. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  20. Unilateral approval - Is it working?

    International Nuclear Information System (INIS)

    MDS Nordion, owned by Canadian based MDS Inc., designs, manufactures and uses transport packages for the distribution of radioactive materials used in the medical, research and sterilisation industries. Each of these packages must be proven to meet the International Atomic Energy Agency (IAEA) transport regulations. This paper will explore the unilateral approval concept as well as provide examples of its implementation. The IAEA transport regulations are recognised and implemented across the world. They include the unilateral approval concept of a single competent authority approval of the package design. Although the performance standards set by the IAEA regulations for Type B(U) packages have been accepted and implemented in national legislation, national authorities tend to require additional reviews of the safety analysis report. Case studies will be presented to demonstrate that the concept of unilateral approval is not applied consistently between all IAEA member states, and that this has impeded the efficient transport of radioactive material. The studies also show that these additional reviews have not resulted in changes to the design of a transport package. The lack of recognition of the IAEA unilateral approval for transport packages is a barrier to the effective transport of packages. These additional reviews require allocation of resources for both the company and the regulatory agency. As a responsible partner in a very unique industry, MDS Nordion encourages all IAEA member states to accept Type B(U) transport certificate from other jurisdictions without requiring additional review or endorsement. In this respect, the collaboration of the competent authorities is important to reduce this regulatory impediment and allowing the effective transport of radioactive material. (author)

  1. Robust procedures in chemometrics

    DEFF Research Database (Denmark)

    Kotwa, Ewelina

    not resistant towards outliers (which are known to be more the rule than the exception for empirical data). That is the reason for robust methods being a valuable tool for both semi-automated detection of outliers and model building. The approach adapted in this thesis, can be split in two main parts......: 1. applying a multivariate and multi-way data analytical frame-work in fields where less sophisticated data analysis methods are currently used, and 2. developing new, more robust alternatives to already existing multivariate tools. The first part of the study was realised by applying two- and three...... qualitative properties of the analysed data. The broad theoretical background of robust procedures was given as a very useful supplement to the classical methods, and a new tool, based on robust PCA, aiming at identifying Rayleigh and Raman scatters in excitation-mission (EEM) data was developed. The results...

  2. 76 FR 21673 - Alternative Efficiency Determination Methods and Alternate Rating Methods

    Science.gov (United States)

    2011-04-18

    ...-substantiation of an AEDM or ARM as a result of a change in standard or test procedure. 76 FR 12492 (March 7...; ] DEPARTMENT OF ENERGY 10 CFR Part 431 RIN 1904-AC46 Alternative Efficiency Determination Methods and Alternate Rating Methods AGENCY: Office of Energy Efficiency and Renewable Energy, Department of Energy....

  3. COLLABORATIVE PROCEDURE TO ACHIEVE AN EFFECTIVE JURISDICTIONAL TUTELAGE

    Directory of Open Access Journals (Sweden)

    Darilê Marques da Matta

    2015-12-01

    Full Text Available Set in a constitutional context, the procedure should be an effective instrument for the guarantee and realization of rights. Attentive to the needs imposed by the state of Law, the new Civil Procedure Code, approved this year, 2 015, seeks to settle several constitutional guarantees, for the purpose of making the procedure more effective. From the inclusion of collaborative institutes, the new Civil Procedure C ode introduces the concept of self-composition and cooperation of procedural agents to achieve, timely, effective jurisdictional tutelage.

  4. Epclusa Approved for Chronic Hepatitis C

    Science.gov (United States)

    ... news/fullstory_159609.html Epclusa Approved for Chronic Hepatitis C Combination drug treats six major forms of ... to treat the six major strains of chronic hepatitis C virus (HCV). Epclusa combines sofosbuvir, FDA-approved ...

  5. Drugs Approved for Colon and Rectal Cancer

    Science.gov (United States)

    ... Professionals Questions to Ask about Your Treatment Research Drugs Approved for Colon and Rectal Cancer This page ... and rectal cancer that are not listed here. Drugs Approved for Colon Cancer Avastin (Bevacizumab) Bevacizumab Camptosar ( ...

  6. Ethics Review Committee approval and informed consent: an analysis of biomedical publications originating from Sri Lanka

    Directory of Open Access Journals (Sweden)

    Siriwardhana Chesmal

    2008-02-01

    Full Text Available Abstract Background International guidelines on research have focused on protecting research participants. Ethical Research Committee (ERC approval and informed consent are the cornerstones. Externally sponsored research requires approval through ethical review in both the host and the sponsoring country. This study aimed to determine to what extent ERC approval and informed consent procedures are documented in locally and internationally published human subject research carried out in Sri Lanka. Methods We obtained ERC approval in Sri Lanka and the United Kingdom. Theses from 1985 to 2005 available at the Postgraduate Institute of Medicine (PGIM library affiliated to the University of Colombo were scrutinised using checklists agreed in consultation with senior research collaborators. A Medline search was carried out with MeSH major and minor heading 'Sri Lanka' as the search term for international publications originating in Sri Lanka during 1999 to 2004. All research publications from CMJ during 1999 to 2005 were also scrutinized. Results Of 291 theses, 34% documented ERC approvals and 61% documented obtaining consent. From the international journal survey, 250 publications originated from Sri Lanka of which only 79 full text original research publications could be accessed electronically. Of these 38% documented ERC approval and 39% documented obtaining consent. In the Ceylon Medical Journal 36% documented ERC approval and 37% documented obtaining consent. Conclusion Only one third of the publications scrutinized recorded ERC approval and procurement of informed consent. However, there is a positive trend in documenting these ethical requirements in local postgraduate research and in the local medical journal.

  7. 48 CFR 833.214 - Alternative dispute resolution (ADR).

    Science.gov (United States)

    2010-10-01

    ... Alternative dispute resolution (ADR). Contracting officers and contractors are encouraged to use alternative dispute resolution (ADR) procedures. CBCA guidance on ADR may be obtained at http://www.cbca.gsa.gov. ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Alternative...

  8. 28 CFR 35.176 - Alternative means of dispute resolution.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Alternative means of dispute resolution... DISABILITY IN STATE AND LOCAL GOVERNMENT SERVICES Compliance Procedures § 35.176 Alternative means of dispute resolution. Where appropriate and to the extent authorized by law, the use of alternative means of...

  9. 28 CFR 2.93 - Travel approval.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Travel approval. 2.93 Section 2.93... Travel approval. (a) A parolee's Supervision Officer may approve travel outside the district of... possibilities. (3) Recurring travel across a district boundary, not to exceed fifty miles outside the...

  10. 40 CFR 123.61 - Approval process.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Approval process. 123.61 Section 123... REQUIREMENTS Program Approval, Revision, and Withdrawal § 123.61 Approval process. (a) After determining that a...; and (6) Briefly outline the fundamental aspects of the State's proposed program, and the process...

  11. 40 CFR 145.31 - Approval process.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Approval process. 145.31 Section 145.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE UIC PROGRAM REQUIREMENTS Program Approval, Revision and Withdrawal § 145.31 Approval process....

  12. Waste feed delivery environmental permits and approvals plan

    International Nuclear Information System (INIS)

    This document describes the range of environmental actions, including required permits and other agency approvals, that may affect waste feed delivery (WFD) activities in the Hanford Site's Tank Waste Remediation System (TWRS). This plan expands on the summary level information in the Tank Waste Remediation System Environmental Program Plan (HNF 1773) to address requirements that are most pertinent to WFD. This plan outlines alternative approaches to satisfying applicable environmental standards, and describes selected strategies for acquiring permits and other approvals needed for WFD to proceed. Appendices at the end of this plan provide preliminary cost and schedule estimates for implementing the selected strategies. The rest of this section summarizes the scope of WFD activities, including important TWRS operating information, and describes in more detail the objectives, structure, and content of this plan

  13. 30 CFR 746.14 - Approval, disapproval or conditional approval, of mining plan.

    Science.gov (United States)

    2010-07-01

    ..., of mining plan. 746.14 Section 746.14 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR FEDERAL LANDS PROGRAM REVIEW AND APPROVAL OF MINING PLANS § 746.14 Approval, disapproval or conditional approval, of mining plan. The Secretary shall approve, disapprove...

  14. 14 CFR Special Federal Aviation... - Alternative Communications and Dispatching Procedures

    Science.gov (United States)

    2010-01-01

    ... dispatch communication system. ii. Gaps in communication are not over the entire route, but only over portions of the route. iii. When communication gaps occur, they occur due to one or more of the following... plan or schedule for coming into compliance with the requirements in § 121.99 of this chapter. b....

  15. Nomenclature of the alternative activating pathway of complement*

    OpenAIRE

    1981-01-01

    This terminology note outlines for the first time a standard nomenclature for the alternative activating pathway of complement. It was drafted by a group of experts working under the auspices of the International Union of Immunological Societies (IUIS), and has been approved by the Nomenclature Committee of the IUIS.

  16. Normetex Pump Alternatives Study

    Energy Technology Data Exchange (ETDEWEB)

    Clark, Elliot A.

    2013-04-25

    A mainstay pump for tritium systems, the Normetex scroll pump, is currently unavailable because the Normetex company went out of business. This pump was an all-metal scroll pump that served tritium processing facilities very well. Current tritium system operators are evaluating replacement pumps for the Normetex pump and for general used in tritium service. An all-metal equivalent alternative to the Normetex pump has not yet been identified. 1. The ideal replacement tritium pump would be hermetically sealed and contain no polymer components or oils. Polymers and oils degrade over time when they contact ionizing radiation. 2. Halogenated polymers (containing fluorine, chlorine, or both) and oils are commonly found in pumps. These materials have many properties that surpass those of hydrocarbon-based polymers and oils, including thermal stability (higher operating temperature) and better chemical resistance. Unfortunately, they are less resistant to degradation from ionizing radiation than hydrocarbon-based materials (in general). 3. Polymers and oils can form gaseous, condensable (HF, TF), liquid, and solid species when exposed to ionizing radiation. For example, halogenated polymers form HF and HCl, which are extremely corrosive upon reaction with water. If a pump containing polymers or oils must be used in a tritium system, the system must be designed to be able to process the unwanted by-products. Design features to mitigate degradation products include filters and chemical or physical traps (eg. cold traps, oil traps). 4. Polymer components can work in tritium systems, but must be replaced regularly. Polymer components performance should be monitored or be regularly tested, and regular replacement of components should be viewed as an expected normal event. A radioactive waste stream must be established to dispose of used polymer components and oil with an approved disposal plan developed based on the facility location and its regulators. Polymers have varying

  17. Comparison of Alternative Processes for Support Decisions

    Directory of Open Access Journals (Sweden)

    Manuel Martínez-Álvarez

    2014-08-01

    Full Text Available There are many tasks that revolve around combinatorial analysis problems, same tasks found in Decision Support Systems (DSS as most of these are responsible for assessing a number of possibilities to deliver the best options. Within the analysis of possible solutions is performed by the DSS there are alternative procedures inside the engine for making decisions that involve them. As part of these alternative procedures today has highlighted the use of metaheuristics, thus in this paper we propose a comparison of some of them trying to broaden the spectrum we have for the applications nowadays.

  18. 75 FR 48302 - Notice of Request for Extension of Approval of an Information Collection; Credit Account Approval...

    Science.gov (United States)

    2010-08-10

    ... Approval of an Information Collection; Credit Account Approval for Reimbursable Services AGENCY: Animal and... information collection associated with credit account approval for reimbursable services. DATES: We will... account approval for reimbursable services, contact Mrs. Kris Caraher, User Fees Section Head,...

  19. 76 FR 70830 - Proposed Information Collection (Procedures, and Security for Government Financing) Activity...

    Science.gov (United States)

    2011-11-15

    ... AFFAIRS Proposed Information Collection (Procedures, and Security for Government Financing) Activity... Government Financing. OMB Control Number: 2900-0688. Type of Review: Extension of a currently approved..., Security for Government Financing--10 hours. Estimated Average Burden per Respondent: a. VAAR...

  20. 77 FR 30371 - Procedures for Monitoring Bank Secrecy Act Compliance and Fair Credit Reporting: Technical...

    Science.gov (United States)

    2012-05-23

    ..., Procedures for Monitoring Bank Secrecy Act Compliance and Fair Credit Reporting: Technical Amendments (76 FR..., approved by the bank's board of directors, and noted in the minutes. (2) Customer identification...

  1. Licensing failure in the European decentralised procedure.

    Science.gov (United States)

    Langedijk, Joris; Ebbers, Hans C; Mantel-Teeuwisse, Aukje K; Kruger-Peters, Alexandra G; Leufkens, Hubert G M

    2016-05-25

    The majority of the licensing applications in the European Union are submitted via the decentralised procedure. Little is known about licensing failure (i.e. refusal or withdrawal of a marketing authorisation application) in the EU decentralised procedure compared to the EU centralised procedure and the approval procedure in the United States. The study aim was to determine the frequency of and determinants for licensing failure of marketing authorisation applications submitted via this procedure. We assessed procedures that failed between 2008 and 2012 with The Netherlands as leading authority and assessed the remaining major objections. In total 492 procedures were completed, of which 48 (9.8%) failed: 8 refused, 40 withdrawn. A wide variety of major objections was identified and included both quality (48 major objections) and clinical (45 major objections) issues. The low failure rate may be related to the regular interaction between competent authorities and applicants during the procedure. Some degree of licensing failure may be inevitable, as it may also be affected by the financial feasibility or willingness to resolve major objections, as well as other reasons to withdraw an application besides the raised major objections. PMID:26493584

  2. Approval of radioactive consumer goods

    International Nuclear Information System (INIS)

    The 1980 Euratom Directive obliges the UK to draw up a system of prior authorization for the use of radioactive substances in a range of consumer products, and the Government intends to make regulations to fulfil the requirements of the Directive. These regulations will empower NRPB to approve such products prior to their supply to the public. In this brief article, the NRPB reviews the criteria against which to consider any proposed use of radioactive substances, considers radiological production standards for products and discusses the questions of the labelling of radioactive consumer goods. (UK)

  3. Innovative and Alternative Technology Assessment Manual

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-02-01

    This four chapter, six appendix manual presents the procedures and methodology as well as the baseline costs and energy information necessary for the analysis and evaluation of innovative and alternative technology applications submitted for federal grant assistance under the innovative and alternative technology provisions of the Clean Water Act of 1977. The manual clarifies and interprets the intent of Congress and the Environmental Protection Agency in carrying out the mandates of the innovative and alternative provisions of the Clean Water Act of 1977. [DJE 2005

  4. Emergency procedure planning to mitigate event progression

    International Nuclear Information System (INIS)

    The emergency procedure guidelines (EPGs) specify actions to control key parameters symptomatically, using every possible system to mitigate event response. When EPGs are implemented as plant-specific emergency operating procedures (EOPs), alternate system instructions are incorporated in addition to standard emergency system instructions. These alternative systems were previously excluded because their event mitigation potential had not been considered. However, pre-planning with the DOP implementation program allows the alternate systems to be available to back up emergency systems if needed, so that if the plant gets to extraordinary or unusual conditions, the operator will have appropriate response instructions and methods. These alternative systems are used to maintain adequate core cooling and decay heat removal, thereby preventing an event from progressing to a severe accident to the maximum extent possible

  5. 48 CFR 6302.30 - Alternative dispute resolution methods (Rule 30).

    Science.gov (United States)

    2010-10-01

    ... TRANSPORTATION BOARD OF CONTRACT APPEALS RULES OF PROCEDURE 6302.30 Alternative dispute resolution methods (Rule... Alternative Dispute Resolution (ADR): Settlement Judges and Mini-Trials. These procedures are designed to... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Alternative...

  6. Alaska Regional Energy Resources Planning Project. Phase 2: coal, hydroelectric and energy alternatives. Volume I. Beluga Coal District Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rutledge, G.; Lane, D.; Edblom, G.

    1980-01-01

    This volume deals with the problems and procedures inherent in the development of the Beluga Coal District. Socio-economic implications of the development and management alternatives are discussed. A review of permits and approvals necessary for the initial development of Beluga Coal Field is presented. Major land tenure issues in the Beluga Coal District as well as existing transportation routes and proposed routes and sites are discussed. The various coal technologies which might be employed at Beluga are described. Transportation options and associated costs of transporting coal from the mine site area to a connecting point with a major, longer distance transportation made and of transporting coal both within and outside (exportation) the state are discussed. Some environmental issues involved in the development of the Beluga Coal Field are presented. (DMC)

  7. The revival of Phage Therapy to fight Antimicrobial Resistance (AMR) – Part III: What about patent protection and alternative incentives?

    DEFF Research Database (Denmark)

    Minssen, Timo

    2014-01-01

    effective and sustainable solutions. These are alternative models for recovering R&D costs in drugs & devices. Delinkage relies on prizes and grants instead of patent-protected sales above marginal cost. Delinkage models can take various shapes and may be characterized by a wide array of different financial......, however, would face a tough battle to overcome the “additional features that add significantly more” and “not identical” thresholds set by Prometheus and Myriad. Another example with even better prospects for patentability relates to genetically modified phages that are – due to human intervention...... partnerships (PPPs) and the funding of clinical trials through public entities (cf. the EU’s IMI and Phagoburn project). Streamlining the market approval procedure and creating specific regulatory exclusivities (cf. the US GAIN act ) might also help. Moreover, various delinkage models could offer highly...

  8. Mipomersen sodium: first global approval.

    Science.gov (United States)

    Hair, Philip; Cameron, Fiona; McKeage, Kate

    2013-04-01

    Mipomersen sodium (Kynamro™) (henceforth mipomersen) is a second-generation antisense oligonucleotide inhibitor of apolipoprotein B-100, which is the main structural component of atherogenic lipid particles. Mipomersen is administered via subcutaneous injection and is indicated as adjunctive treatment for homozygous familial hypercholesterolaemia (HoFH). The drug was developed by Isis Pharmaceuticals, which now collaborates with Genzyme Corporation for on-going development and product marketing. Multinational phase III trials of mipomersen as adjunctive therapy were completed in patients with HoFH, severe FH, heterozygous FH (HeFH) with coronary artery disease (CAD), and in those with hypercholesterolaemia at high risk of CAD. Mipomersen 200 mg once weekly has been approved in the USA as an adjunct to lipid-lowering medications and diet in HoFH patients and is undergoing regulatory review in the EU for the same indication. Genzyme is also conducting a multinational phase III, open-label extension study to evaluate long-term treatment in HoFH and HeFH patients, as well as a multinational trial to evaluate a three-times-per-week mipomersen regimen in patients with severe FH. This article summarises the milestones in the development of once-weekly, subcutaneous mipomersen leading to this first approval. PMID:23564617

  9. Complementary and Alternative Medicine

    Science.gov (United States)

    ... Help a Friend Who Cuts? Complementary and Alternative Medicine KidsHealth > For Teens > Complementary and Alternative Medicine Print ... replacement. continue How Is CAM Different From Conventional Medicine? Conventional medicine is based on scientific knowledge of ...

  10. 76 FR 20804 - Agency Information Collection Activities: Requests for Comments; Clearance of a Renewed Approval...

    Science.gov (United States)

    2011-04-13

    ... Renewed Approval of Information Collection(s): Procedures for Transportation Workplace Drug and Alcohol... tests conducted and actions taken to ensure safety in the workplace and/or is necessary because under... notice in the Federal Register in accordance with the Paperwork Reduction Act of 1995, Public Law...

  11. 78 FR 41974 - Agency Information Collection Activities: Requests for Comments; Clearance of a Renewed Approval...

    Science.gov (United States)

    2013-07-12

    ... Renewed Approval of Information Collection(s): Procedures for Transportation Workplace Drug and Alcohol... tests conducted and actions taken to ensure safety in the workplace and/or is necessary because under... notice in the Federal Register in accordance with the Paperwork Reduction Act of 1995, Public Law...

  12. 78 FR 50422 - Medical Devices; Availability of Safety and Effectiveness Summaries for Premarket Approval...

    Science.gov (United States)

    2013-08-19

    ... the documents at http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/DeviceApprovalsand...-0724, FDA-2013-M-0738, and FDA-2013-M-0758] Medical Devices; Availability of Safety and Effectiveness...., Docket No. Applicant Trade name Approval date P120016, FDA-2013-M-0592..... Cardiva Medical, Inc....

  13. 75 FR 71687 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2010-11-24

    ... Request; Nomination Application for the U.S. EPA Montreal Protocol Awards; EPA ICR No. 2389.01, OMB... review and approval according to the procedures prescribed in 5 CFR 1320.12. On July 7, 2010 (75 FR 39012... . Title: Nomination Application for the U.S. EPA Montreal Protocol Awards ICR numbers: EPA ICR No....

  14. 78 FR 11640 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Science.gov (United States)

    2013-02-19

    ... approval according to the procedures prescribed in 5 CFR 1320.12. On September 10, 2012 (77 FR 55470), EPA... treaty The Montreal Protocol on Substances That Deplete the Ozone Layer (Protocol) and Title VI of the... Montreal Protocol. EPA has implemented an electronic reporting system that allows regulated entities...

  15. 76 FR 65721 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2011-10-24

    ... review and approval according to the procedures prescribed in 5 CFR 1320.12. On March 2, 2011 (76 FR... the Montreal Protocol on Substances that Deplete the Ozone Layer (Protocol). The information... regulated industries to the EPA and recordkeeping of key documents to ensure compliance with the...

  16. 77 FR 14461 - Approval of Noise Compatibility Program for W.K. Airport, Battle Creek, MI

    Science.gov (United States)

    2012-03-09

    ... flight procedures for noise abatement were proposed by the airport operator. DATES: Effective Date: The... period shall be deemed to be an approval of such program, seven proposed actions for noise abatement... Creek, Michigan, under the provisions of 49 U.S.C. 47501 et seq. (formerly the Aviation Safety and...

  17. 77 FR 7147 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2012-02-10

    ... review and approval according to the procedures prescribed in 5 CFR 1320.12. On September 21, 2011 (76 FR... Constitution Ave. NW., Washington, DC. The EPA/DC Public Reading Room is open from 8:30 a.m. to 4:30 p.m... landfill criteria promulgated under paragraph (1) of Section 4004(a) and Section 1008(a)(3). Section...

  18. 76 FR 41705 - Approval and Promulgation of Implementation Plans; New York; Revised Format of Materials Being...

    Science.gov (United States)

    2011-07-15

    .... Part 212, General Process 9/22/94 9/25/01, 66 FR 48961 Emission Sources. Part 213, Contaminant... as a SIP revision. Part 226, Solvent Metal Cleaning 5/7/03 1/23/04, 69 FR 3240 Processes. Part 227... approved, they become part of the SIP. On May 22, 1997 (62 FR 27968), EPA revised the procedures...

  19. 13 CFR 127.303 - How will SBA select and identify approved certifiers?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false How will SBA select and identify approved certifiers? 127.303 Section 127.303 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT ASSISTANCE PROCEDURES Certification of EDWOSB or WOSB...

  20. 13 CFR 127.304 - How does a concern obtain certification from an approved certifier?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false How does a concern obtain certification from an approved certifier? 127.304 Section 127.304 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT ASSISTANCE PROCEDURES Certification of EDWOSB or...

  1. 76 FR 72918 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2011-11-28

    ... approval according to the procedures prescribed in 5 CFR 1320.12. On July 11, 2011 (76 FR 40723), EPA...) established a matching State Water Pollution Control Revolving Fund Program with funds that had to be... implement Section 606 of the CWA. The 1987 Act declares that water pollution control revolving funds...

  2. 75 FR 67388 - Credit Watch Termination Initiative; Termination of Direct Endorsement (DE) Approval

    Science.gov (United States)

    2010-11-02

    ... published a notice (64 FR 26769), on its procedures for terminating Origination Approval Agreements with FHA...-8000; telephone (202) 708-2830 (this is not a toll-free number). Persons with hearing or speech... Freedom Mortgage Corp......... 907 Pleasant Valley Fort Worth....... 10/4/10 Denver. Ave. Mount Laurel,...

  3. 77 FR 28380 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2012-05-14

    ... for review and approval according to the procedures prescribed in 5 CFR 1320.12. On May 9, 2011 (76 FR... acetal resin; acrylic and modacrylic fiber; hydrogen fluoride and polycarbonate production. ] Estimated... following four categories: Polycarbonates (PC) Production, Acrylic and Modacrylic Fibers (AMF)...

  4. 76 FR 9776 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2011-02-22

    ... and approval according to the procedures prescribed in 5 CFR 1320.12. On September 3, 2010 (75 FR.... Abstract: The goal of the SunWise School Program is to teach children and their caregivers how to protect... progress and evaluating the effectiveness of an environmental and public health education program where...

  5. Decentralizing the French licensing procedure for nuclear power plants

    International Nuclear Information System (INIS)

    One important change in French nuclear policy is marked by the government's decision to decentralize and democratize the licensing procedures. This means a reshuffle of competencies, of the energy plants of the provinces, and the establishment of new institutions at local, regional, and national levels. The new type of licensing procedure has already proved its merits in dealing with the five frozen sites, four of which have so far been approved. (orig./HP)

  6. Decentralizing the French licensing procedure for nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Rapin, M.

    1982-01-01

    One important change in French nuclear policy is marked by the government's decision to decentralize and democratize the licensing procedures. This means a reshuffle of competencies, of the energy plants of the provinces, and the establishment of new institutions at local, regional, and national levels. The new type of licensing procedure has already proved its merits in dealing with the five frozen sites, four of which have so far been approved.

  7. 46 CFR 50.20-30 - Alternative materials or methods of construction.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Alternative materials or methods of construction. 50.20-30 Section 50.20-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING GENERAL PROVISIONS Plan Submittal and Approval § 50.20-30 Alternative materials or methods of construction. (a) When new or...

  8. 25 CFR 11.1012 - Dispositional alternatives.

    Science.gov (United States)

    2010-04-01

    ... LAW AND ORDER CODE Juvenile Offender Procedure § 11.1012 Dispositional alternatives. (a) If a minor has been adjudged a juvenile offender, the children's court may make the following disposition: (1) Place the minor on probation subject to conditions set by the children's court; (2) Place the minor...

  9. An approved personal dosimetry service based on an electronic dosimeter

    International Nuclear Information System (INIS)

    At the Second Conference on Radiation Protection and Dosimetry a paper was presented which, in part, announced the development of an electronic dosimeter to be undertaken in the UK by the National Radiological Protection Board (NRPB) and Siemens Plessey Controls Ltd. This dosimeter was to be of a standard suitable for use as the basis of an approved personal dosimetry service for photon and beta radiations. The project has progressed extremely well and dosimeters and readers are about to become commercially available. The system and the specification of the dosimeter are presented. The NRPB is in the process of applying for approval by the Health and Safety Executive (HSE) to operate as personal monitoring service based on this dosimeter. As part of the approval procedure the dosimeter is being type tested and is also undergoing an HSE performance test and wearer trials. The tests and the wearer trials are described and a summary of the results to date presented. The way in which the service will be organized and operated is described and a comparison is made between the running of the service and others based on passive dosimeters at NRPB

  10. Contents specification criteria for package design approvals in Germany

    International Nuclear Information System (INIS)

    Requirements for a package design for the transport of radioactive and fissile material are established in the Regulations for the Safe Transport of Radioactive Material - 1996 Edition (TS-R-1). Beginning with the first edition in 1961 the Regulations for the Safe Transport of Radioactive Material were developed consequently to a high standard to protect persons, property and the environment from the effects of radiation during the transport of radioactive material by placing the primary reliance on the package design. One important part of the package design approval procedure is to show that all dose rate limits and other requirements relating to radiation shielding are fulfilled when the maximum radioactive contents is considered. The applicant has to find covering parameters for the contents description which will be fixed in the package design approval certificate as maximum permissible parameters. This paper describes the contents description for spent fuel elements and vitrified high level radioactive waste (HAW) from the reprocessing which are acceptable to the Federal Office for Radiation Protection (BfS) as the competent authority for package design approval. Such parameters for spent fuel elements are i.e. enrichment, burn-up, cooling time, or the description by source strengths for gamma and neutron emitters. It is also shown which specific evidences, i.e. for weak areas of the shielding, are requested by BfS. (author)

  11. 14 CFR 93.71 - General operating procedures.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false General operating procedures. 93.71 Section 93.71 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED..., aircraft operating on an ATC-approved IFR flight plan, aircraft operating the Scenic Falls Route...

  12. Policies and Procedures Manual for Special Education in Oklahoma.

    Science.gov (United States)

    Oklahoma State Dept. of Education, Oklahoma City.

    The guide, a support document to the Oklahoma State Plan for Special Education, presents a policies and procedures manual for special education in Oklahoma in accordance with the Education for All Handicapped Children Act (P.L. 94-142). The manual is intended to establish the minimum standards for special education program approval, to establish…

  13. Depleted uranium management alternatives

    International Nuclear Information System (INIS)

    This report evaluates two management alternatives for Department of Energy depleted uranium: continued storage as uranium hexafluoride, and conversion to uranium metal and fabrication to shielding for spent nuclear fuel containers. The results will be used to compare the costs with other alternatives, such as disposal. Cost estimates for the continued storage alternative are based on a life-cycle of 27 years through the year 2020. Cost estimates for the recycle alternative are based on existing conversion process costs and Capital costs for fabricating the containers. Additionally, the recycle alternative accounts for costs associated with intermediate product resale and secondary waste disposal for materials generated during the conversion process

  14. One Stop Centre as a Boon to Property Development Approval Process. A Case Study:City Hall of Kuala Lumpur

    OpenAIRE

    Ibrahim Mohd @ Ahmad; Faizah Ahmad; Ezrin Arbi

    2011-01-01

    The delays in obtaining local authority approvals for land development have become a universal issue in the property development sector. In the past decades, the approval process in Malaysia was accused of having cumbersome and inconsistency procedures. Recently, the Ministry of Housing and Local Government has introduced a new processing system as the innovative initiative called One Stop Centre (OSC) in each local authority meant to expedite the planning, building and land development appro...

  15. Low-Level Presence of New GM Crops: An Issue on the Rise for Countries Where They Lack Approval

    OpenAIRE

    STEIN Alexander Jivraj; Rodriguez Cerezo, Emilio

    2009-01-01

    This study addresses a new issue in the commercialisation of GM crops, namely the occurrence of traces ¿ or "low-level presence" (LLP) ¿ of nationally unapproved GM material in crop imports. The commercialisation of GM crops is a regulated activity and countries have different authorisation procedures. Hence new GM crops are not approved simultaneously. This "asynchronous approval" (AA), in combination with a "zero tolerance" policy to¬wards LLP, is of growing con¬cern for its potential econo...

  16. Multi-criteria approval for evaluating landscape management strategies (Case study: Fruška Gora National Park

    Directory of Open Access Journals (Sweden)

    Lakićević Milena D.

    2015-01-01

    Full Text Available This paper deals with the problem of multi-criteria evaluation of four management strategies for Fruška Gora National Park. The criteria set was defined in ac­cordance with the IUCN guidelines for management of national parks. Four strategies were evaluated by testing preference intensities for each alternative with the respect to each cri­terion. Alternatives with preference above the approval threshold were approved, and a multi-criteria approval matrix was generated. According to the matrix, the most suitable management strategy was identified. It implies an intense protection of natural resources and landscape diversity in the national park by applying bio-engineering measures. This illustrative example proved that multi-criteria approval can be considered as a good deci­sion support tool when there is no need for a deeper insight into cardinal values of criteria weights and alternatives, or if the decision maker has to select few from many of alterna­tives to reduce the decision problem. For a more precise analysis, it is recommended to combine multi-criteria approval with other decision support tools, and future studies might deal with this problem in order to define an alternative framework for decision making in landscape management. [Projekat Ministarstva nauke Republike Srbije, br. 174003: Theory and application of analytic hierarchy process (AHP in multi-criteria decision making under conditions of risk and uncer­tainty (individual and group context

  17. 12 CFR 211.24 - Approval of offices of foreign banks; procedures for applications; standards for approval...

    Science.gov (United States)

    2010-01-01

    ..., or comparable information that permits analysis of the foreign bank's financial condition on a... SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM INTERNATIONAL BANKING OPERATIONS (REGULATION K... administrative matters (such as verification or correction of account information). (4) Suspension of...

  18. 42 CFR 488.61 - Special procedures for approval and re-approval of organ transplant centers.

    Science.gov (United States)

    2010-10-01

    ... described at 42 CFR part 488, subpart A apply to transplant centers, including the periodic review of... described at 42 CFR part 488, subpart A. If the transplant center is found to be in compliance with all the... 42 CFR part 488, subpart A. (3) If CMS determines that a transplant center has met the...

  19. 7 CFR 959.123 - Approval.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Approval. 959.123 Section 959.123 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... consideration to each application for a Certificate of Privilege. Approval of an application, based upon...

  20. 7 CFR 948.123 - Approval.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Approval. 948.123 Section 948.123 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... give prompt consideration to each application for a Certificate of Privilege. Approval of...

  1. 7 CFR 1735.90 - Preliminary approvals.

    Science.gov (United States)

    2010-01-01

    ... preliminary approval to the acquisition or merger. However, the borrower may not obtain additional loan funds...) Before RUS will grant preliminary approval, the borrower shall submit: (1) Merger or acquisition documents required by state law; (2) Acquisition agreements covering the transaction; (3) Any...

  2. 77 FR 6560 - Pesticide Product Registration Approval

    Science.gov (United States)

    2012-02-08

    ... the Federal Register of June 10, 2009 (74 FR 27541) (FRL-8413-2), which announced that Lubrizol, 29400... AGENCY Pesticide Product Registration Approval AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This notice announces Agency approval of an application to register the...

  3. 30 CFR 28.2 - Approved fuses.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Approved fuses. 28.2 Section 28.2 Mineral... MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES General Provisions § 28.2 Approved fuses. (a) On and after the effective date...

  4. 13 CFR 108.370 - Conditional approval.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Conditional approval. 108.370 Section 108.370 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Evaluation and Selection of NMVC Companies § 108.370 Conditional approval....

  5. Ordinal Position, Approval Motivation, and Interpersonal Attraction

    Science.gov (United States)

    Nowicki, Stephen, Jr.

    1971-01-01

    Results of the study suggest that birth-order effects might be included within the wider framework of approval-dependency theory. Females tend to account for a significant share of birth-order effects. More particularly, firstborn females accounted for much of the differences in expressed attraction as well as need for social approval. (Author)

  6. 46 CFR 249.7 - Approval.

    Science.gov (United States)

    2010-10-01

    ... UNDERWRITERS FOR MARINE HULL INSURANCE § 249.7 Approval. (a) Approval of the applicant will be based upon an.... hull insurance market, if U.S. insurers are denied similar access to the hull insurance market in the... to MARAD's attention any discriminatory laws or practices relating to the placement of marine...

  7. E-Approval Plans in Research Libraries

    Science.gov (United States)

    Pickett, Carmelita; Tabacaru, Simona; Harrell, Jeanne

    2014-01-01

    Research libraries have long invested in approval plan services, which offer an economical way to acquire scholarly and scientific publications. Traditional approval plans have evolved and now enable libraries to expand their e-book offerings to better serve researchers. Publishers offer a myriad of e-book purchasing options. These range from…

  8. Radioimmunoassay and related procedures in medicine 1982

    International Nuclear Information System (INIS)

    Of the 77 papers submitted, 69 were included in INIS. The papers included in the proceedings cover the following sessions: reagents and separation procedures; assay for free hormones; assay for biological substances; assay for drugs; data processing; intralaboratory quality control; external surveillance of assay performance; assay service in developing countries; public health applications; clinical applications; alternatives to radioassay

  9. Extended Learning Institute. Policies and Procedures Manual.

    Science.gov (United States)

    Adams, Larry

    This manual describes the Extended Learning Institute (ELI) at John Tyler Community College in Virginia. The ELI is a comprehensive program of instruction using alternative delivery systems (e.g., television, print-based, radio, and newspapers). General procedures and policies are delineated in section I, including registration and student and…

  10. Summative Evaluation of an Alternative Teacher Licensure Program Sponsored by a Large Suburban School Division

    OpenAIRE

    Parker III, George

    2010-01-01

    SUMMATIVE EVALUATION OF AN ALTERNATIVE TEACHER LICENSURE PROGRAM SPONSORED BY A LARGE SUBURBAN SCHOOL DIVISION By George Parker III Glen Earthman, Chair Educational Leadership and Policy Studies (ABSTRACT) The number of alternative licensure programs has increased significantly over the past decade. Faced with critical shortages of public school teachers in several subject areas, the Commonwealth of Virginia first approved an alternative route to licensure in 199...

  11. Polyphase alternating codes

    CERN Document Server

    Markkanen, Markku

    2007-01-01

    This work introduces a method for constructing polyphase alternating codes in which the length of a code transmission cycle can be $p^m$ or $p-1$, where $p$ is a prime number and $m$ is a positive integer. The relevant properties leading to the construction alternating codes and the algorithm for generating alternating codes is described. Examples of all practical and some not that practical polyphase code lengths are given.

  12. Alternative Solar Indices

    Energy Technology Data Exchange (ETDEWEB)

    Lantz, L.J.

    1980-07-01

    Possible alternative Solar Indices which could either be a perturbation from the currently defined Solar Index or possible indices based on current technologies for other media markets are discussed. An overview is given of the current project, including the logic that was utilized in defining its current structure and then alternative indices and definitions are presented and finally, recommendations are made for adopting alternative indices.

  13. On an Alternative Cosmology

    OpenAIRE

    Vankov, A.

    1998-01-01

    The suggested alternative cosmology is based on the idea of barion symmetric universe, in which our home universe is a representative of multitude of typical matter and antimatter universes. This alternative concept gives a physically reasonable explanation of all major problems of the Standard Cosmological Model. Classification Code MSC: Cosmology 524.8 Key words: standard cosmological model, alternative cosmology, barionic symmetry, typical universe, quasars, cosmic rays.

  14. Complex Alternative Splicing

    OpenAIRE

    Park, Jung Woo; Graveley, Brenton R.

    2007-01-01

    Alternative splicing is a powerful means of controlling gene expression and increasing protein diversity. Most genes express a limited number of mRNA isoforms, but there are several examples of genes that use alternative splicing to generate hundreds, thousands, and even tens of thousands of isoforms. Collectively such genes are considered to undergo complex alternative splicing. The best example is the Drosophila Down syndrome cell adhesion molecule (Dscam) gene, which can generate 38,016 is...

  15. Alternators. Experience feedback

    International Nuclear Information System (INIS)

    Study of the technical aspects of various accidents having occured on nuclear alternators operating in the French 900 MW nuclear plant unit, and the respective solutions and possibilities for application to alternators of the 1000 and 1500 MW power plants. Analysis of the accidents on CP 1 program alternators: accidents caused by vibratory fatigue (cracking of the hydraulic connection pipes of the stator winding, cracking of the hydraulic-electric connection between the stator coiling and the output terminals, cracking of the hydrogen cooler finned tubes), pollution by copper oxide of the stator winding cooling water circuit. Accidents on CP 2 alternators: accident on the shaft sealing joint, striking inside the terminal box

  16. Endoscopic third ventriculostomy through lamina terminalis: A feasible alternative to standard endoscopic third ventriculostomy

    Directory of Open Access Journals (Sweden)

    Subodh Raju

    2016-01-01

    Conclusions: Endoscopic transventricular transforaminal LT fenestration with a flexible neuroendoscope is a feasible alternative to the standard ETV when technical difficulties precludes safe performance of the latter procedure.

  17. Comparative Study of Process of Post Approval Change Application Submission and Approval for Marketing Authorization Variations in EU, US, India, Saudi Arabia and Singapore

    Directory of Open Access Journals (Sweden)

    Lokesh M.S

    2015-03-01

    Full Text Available The present research endeavors to shed light onto the role that post approval change management in overcoming non-compliance. The present study has focused on identifying the existing policies and procedure in this area and understanding the underlying concepts for post approval compliance for licenses pertaining to marketing authorization. The study compared and contrasted policies and procedures of regulatory authorities in India, US, EU, Saudi Arabia and Singapore. The major finding of the study indicates that though change management plays a crucial role in the lifecycle of a pharmaceutical. However, lack of defined framework coupled with lack of comprehension of the same has increased the cost of compliance resulting step-motherly treatment being mitigated towards compliance and license maintenance. The initiatives by the ICH with drafting of ICH Q12 guidelines is a welcome step forward and may help the pharmaceutical industry to comply with the regulations.

  18. 5 CFR 7601.102 - Prior approval of outside employment.

    Science.gov (United States)

    2010-01-01

    ... prohibited by statute or Federal regulation, including 5 CFR part 2635. (c) Scope of approval. Approval will... employee's NARA position, the employee shall submit a revised request for approval. (d) Definition...

  19. Hom-alternative algebras and Hom-Jordan algebras

    CERN Document Server

    Makhlouf, Abdenacer

    2009-01-01

    The purpose of this paper is to introduce Hom-alternative algebras and Hom-Jordan algebras. We discuss some of their properties and provide construction procedures using ordinary alternative algebras or Jordan algebras. Also, we show that a polarization of Hom-associative algebra leads to Hom-Jordan algebra.

  20. National Differences in Requirements for Ethical and Competent Authority Approval for a Multinational Vaccine Trial under the EU Directive 2001/20/EC

    Directory of Open Access Journals (Sweden)

    Eva van Doorn

    2015-04-01

    Full Text Available Obtaining approval for a multinational vaccine trial from an ethics committee and the national competent authority of different Member States of the European Union (EU is challenging under clinical trial Directive 2001/20/EC because of the differences in the implementation of the directive in national laws of Member States. In this review the national differences in requirements for ethical and competent authority approval are illustrated. The national ethical and competent authority review procedures in Finland, Hungary, The Netherlands, Norway and Slovenia are described under the EU trial directive after discussing the provisions of the trial directive related to both review procedures. The review illustrates the differences between the countries in the documents that have to be submitted for the review procedures, the submission procedures and the language requirements of the documents, the organization of the ethics committees and the role of the competent authority in the approval procedure.

  1. 10 CFR 72.230 - Procedures for spent fuel storage cask submittals.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Procedures for spent fuel storage cask submittals. 72.230... STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Approval of Spent Fuel Storage Casks § 72.230 Procedures for spent fuel storage cask...

  2. Alternative Devices for Taking Insulin

    Science.gov (United States)

    ... KB). Alternate Language URL Alternative Devices for Taking Insulin Page Content On this page: What alternative devices ... the skin. [ Top ] What alternative devices for taking insulin are available? Insulin pens provide a convenient, easy- ...

  3. Are Condorcet procedures so bad according to the reinforcement axiom?

    OpenAIRE

    Courtin, Sébastien; Mbih, Boniface; Moyouwou, Issofa

    2014-01-01

    A Condorcet social choice procedure elects the candidate that beats every other candidate under simple majority when such a candidate exists. The reinforcement axiom roughly states that given two groups of individuals, if these two groups select the same alternative, then this alternative must also be selected by their union. Condorcet social choice procedures are known to violate this axiom. Our goal in this paper is to put this important voting theory result into perspective. We then procee...

  4. Brandmodstandsbidrag for alternative isoleringsmaterialer

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place

    2001-01-01

    Resume af rapport om alternative isoleringsmaterialers brandmodstandsbidrag, udarbejdet af Dansk Brandteknisk Institut under Energistyrelsens udviklingsprogram "Miljø- og arbejdsmiljøvenlig isolering"......Resume af rapport om alternative isoleringsmaterialers brandmodstandsbidrag, udarbejdet af Dansk Brandteknisk Institut under Energistyrelsens udviklingsprogram "Miljø- og arbejdsmiljøvenlig isolering"...

  5. Anvendelse af alternative isoleringsmaterialer

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place

    2003-01-01

    Resume af By og Byg Anvisning 207 om anvendelse af alternative isoleringsmaterialer, udarbejdet af Statens Byggeforskningsinstitut under udviklingsprogrammet "Miljø- og arbejdsmiljøvenlig isolering"......Resume af By og Byg Anvisning 207 om anvendelse af alternative isoleringsmaterialer, udarbejdet af Statens Byggeforskningsinstitut under udviklingsprogrammet "Miljø- og arbejdsmiljøvenlig isolering"...

  6. Procedures in diagnostic radiology

    International Nuclear Information System (INIS)

    A book has been written on the procedures used in diagnostic radiology covering the subject areas of the urinary tract, gastrointestinal and biliary tracts, vascular radiology, cerebral angiography and arthrography. The explanation of each procedure follows a common layout which includes indications, equipment, technique and complications. The book is intended to be a reference book for radiology trainees learning to do practical procedures for the first time and also for practising radiologists not habitually performing certain diagnostic procedures. (UK)

  7. Joint Test Report For Validation of Alternatives to Aliphatic Isocyanate Polyurethanes

    Science.gov (United States)

    Lewis, Pattie

    2007-01-01

    National Aeronautics and Space Administration (NASA) and Air Force Space Command (AFSPC) have similar missions and therefore similar facilities and structures in similar environments. The standard practice for protecting metallic substrates in atmospheric environments is the application of an applied coating system. The most common topcoats used in coating systems are polyurethanes that contain isocyanates. Isocyanates are classified as potential human carcinogens and are known to cause cancer in animals. The primary objective of this effort was to demonstrate and validate alternatives to aliphatic isocyanate polyurethanes resulting in one or more isocyanate-free coatings qualified for use at AFSPC and NASA installations participating in this project. This joint Test Report (JTR) documents the results of the laboratory and field testing as well as any test modifications made during the execution of the testing. The technical stakeholders agreed upon test procedure modifications documented in this document. This JTR is made available as a reference for future pollution prevention endeavors by other NASA centers, the Department of Defense and commercial users to minimize duplication of effort. All coating system candidates were tested using approved NASA and AFSPC standard coating systems as experimental controls. This study looked at eight alternative coating systems and two control coating systems and was divided into Phase I Screening Tests, Phase II Tests, and Field Testing. The Phase I Screening Tests were preliminary tests performed on all the selected candidate coating systems. Candidate coating systems that did not meet the acceptance criteria of the screening tests were eliminated from further testing. Phase I Screening Tests included: Ease of Application, Surface Appearance, Dry-To-Touch (Sanding), Accelerated Storage Stability, Pot Life (Viscosity), Cure Time (Solvent Rubs), Cleanability, Knife Test, Tensile (pull-off) Adhesion, and X-Cut Adhesion by Wet

  8. Approving of personal dosimeter services

    International Nuclear Information System (INIS)

    The Swedish regulation SSI FS 98:5 requires that radiological workers of category A use dosemeters from an approved personal dosimetry service. The regulation also includes certain specific dosimeter requirements, which are based on those presented in the Technical Recommendations by the European Commission (Report EUR 14852 EN, 1994). All services have been tested for their ability to determine Hp(10) and some of them to determine Hp(0.07) at one radiation quality. The test was performed in the interval 0.2 mSv to 100 mSv at three different dose equivalents unknown to the system owner. The 11 services operating in Sweden at the moment use 5 different types of dosimeters. The five unique systems have been tested regarding the angular and energy dependence of the response of the dosimeters. The dosimeters were irradiated to a personal dose equivalent of about 1 mSv at three photon energies and at four angles (0, 20, 40 and 60 deg. resp. ) both vertically and horizontally rotated. Only 2 of the services determine Hp(0.07) for beta and gamma radiation and were tested for this quantity. The test results for Hp(10) are all except two within the trumpet curve. For the unique systems it is shown that the uncertainty related to angular response at a specified energy is within the required ±40 % except for the lowest X-ray quality at 40 kV. The response is more dependent on photon energy than on the direction of the photon radiation and the choice of radiation quality for the calibration is of great importance for the system performance

  9. Crew procedures development techniques

    Science.gov (United States)

    Arbet, J. D.; Benbow, R. L.; Hawk, M. L.; Mangiaracina, A. A.; Mcgavern, J. L.; Spangler, M. C.

    1975-01-01

    The study developed requirements, designed, developed, checked out and demonstrated the Procedures Generation Program (PGP). The PGP is a digital computer program which provides a computerized means of developing flight crew procedures based on crew action in the shuttle procedures simulator. In addition, it provides a real time display of procedures, difference procedures, performance data and performance evaluation data. Reconstruction of displays is possible post-run. Data may be copied, stored on magnetic tape and transferred to the document processor for editing and documentation distribution.

  10. The prophylactic use of C1 inhibitor in hereditary angioedema patients undergoing invasive surgical procedures: a retrospective study

    OpenAIRE

    Gavigan, Geneviève; Yang, William H; Santucci, Stephanie; Harrison, Rachel; Karsh, Jacob

    2014-01-01

    Background Hereditary Angioedema (HAE) is a rare autosomal dominant condition characterized by episodic angioedema, which may be triggered by invasive procedures and surgery. C1 inhibitor (C1 INH) was approved in the United States and Canada in 2009 and 2010, respectively, for the treatment of acute attacks. Most recently in April 2013, it was approved in Europe for short-term prophylaxis (STP), prior to medical, dental, or surgical procedures, to prevent HAE attacks in both children and adul...

  11. Comparative Validity of the Shedler and Westen Assessment Procedure-200

    Science.gov (United States)

    Mullins-Sweatt, Stephanie N.; Widiger, Thomas A.

    2008-01-01

    A predominant dimensional model of general personality structure is the five-factor model (FFM). Quite a number of alternative instruments have been developed to assess the domains of the FFM. The current study compares the validity of 2 alternative versions of the Shedler and Westen Assessment Procedure (SWAP-200) FFM scales, 1 that was developed…

  12. Modern phosphate glass dosimeters - the alternative in personal monitoring

    International Nuclear Information System (INIS)

    After a pattern approval by the PTB a new automatic photoluminescence dosimetry (PLD) system has been recently introduced as an official dosimeter into routine monitoring. As an example this dosimeter characterizes the recent developments in personal dosimetry. The paper describes the dosimetric properties of the flat glass dosimeter using the readout system Toshiba FGD-10 and aspects of application in comparison to other dosimeter types. The flat glass dosimeter is today an attractive alternative to the still used film and thermoluminescence dosimeters. (orig.)

  13. Drugs Approved for Gestational Trophoblastic Disease

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for gestational trophoblastic disease. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  14. FDA Approves Eye Implant for Aging Boomers

    Science.gov (United States)

    ... medlineplus/news/fullstory_159648.html FDA Approves Eye Implant for Aging Boomers Tiny lens reshapes cornea to ... 2016 THURSDAY, June 30, 2016 (HealthDay News) -- An implant that helps the aging eye focus on small ...

  15. FDA Approves Implant to Battle Opioid Addiction

    Science.gov (United States)

    ... gov/medlineplus/news/fullstory_159050.html FDA Approves Implant to Battle Opioid Addiction Experts say steady dosing ... 26, 2016 (HealthDay News) -- A new long-acting implant that can help treat people addicted to heroin ...

  16. Drugs Approved for Head and Neck Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for head and neck cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  17. Procedure generation and verification

    International Nuclear Information System (INIS)

    The Department of Energy has used Artificial Intelligence of ''AI'' concepts to develop two powerful new computer-based techniques to enhance safety in nuclear applications. The Procedure Generation System, and the Procedure Verification System, can be adapted to other commercial applications, such as a manufacturing plant. The Procedure Generation System can create a procedure to deal with the off-normal condition. The operator can then take correct actions on the system in minimal time. The Verification System evaluates the logic of the Procedure Generator's conclusions. This evaluation uses logic techniques totally independent of the Procedure Generator. The rapid, accurate generation and verification of corrective procedures can greatly reduce the human error, possible in a complex (stressful/high stress) situation

  18. Procedure system principles

    International Nuclear Information System (INIS)

    Procedures establish how an organization performs specific tasks to accomplish its basic goals and objectives. In 1990, the US Department of Energy (DOE) started the process of defining requirements to be used for procedures throughout the DOE nuclear complex. In response to the customer needs of the complex, the department's initial steps in this process were to develop two documents: a writer's guide for technical procedures and the principles of procedure writing upon which it was based. The US Nuclear Regulatory Commission and Institute for Nuclear Power Operations literature addresses the control and use of procedures. There was, however, no regulatory guidance on developing and managing a procedure system. In 1991, an effort was undertaken to provide such guidance for DOE nuclear facilities. A companion paper by Grider and Plung describes how a performance-tested advisory group developed this guidance. This paper describes the procedure system principles that were developed through this process

  19. Comparing MTI randomization procedures to blocked randomization.

    Science.gov (United States)

    Berger, Vance W; Bejleri, Klejda; Agnor, Rebecca

    2016-02-28

    Randomization is one of the cornerstones of the randomized clinical trial, and there is no shortage of methods one can use to randomize patients to treatment groups. When deciding which one to use, researchers must bear in mind that not all randomization procedures are equally adept at achieving the objective of randomization, namely, balanced treatment groups. One threat is chronological bias, and permuted blocks randomization does such a good job at controlling chronological bias that it has become the standard randomization procedure in clinical trials. But permuted blocks randomization is especially vulnerable to selection bias, so as a result, the maximum tolerated imbalance (MTI) procedures were proposed as better alternatives. In comparing the procedures, we have somewhat of a false controversy, in that actual practice goes uniformly one way (permuted blocks), whereas scientific arguments go uniformly the other way (MTI procedures). There is no argument in the literature to suggest that the permuted block design is better than or even as good as the MTI procedures, but this dearth is matched by an equivalent one regarding actual trials using the MTI procedures. So the 'controversy', if we are to call it that, pits misguided precedent against sound advice that tends to be ignored in practice. We shall review the issues to determine scientifically which of the procedures is better and, therefore, should be used. PMID:26337607

  20. Alternative loop rings

    CERN Document Server

    Goodaire, EG; Polcino Milies, C

    1996-01-01

    For the past ten years, alternative loop rings have intrigued mathematicians from a wide cross-section of modern algebra. As a consequence, the theory of alternative loop rings has grown tremendously. One of the main developments is the complete characterization of loops which have an alternative but not associative, loop ring. Furthermore, there is a very close relationship between the algebraic structures of loop rings and of group rings over 2-groups. Another major topic of research is the study of the unit loop of the integral loop ring. Here the interaction between loop rings and group ri

  1. Ultrasound-guided interventional procedures around the shoulder.

    Science.gov (United States)

    Messina, Carmelo; Banfi, Giuseppe; Orlandi, Davide; Lacelli, Francesca; Serafini, Giovanni; Mauri, Giovanni; Secchi, Francesco; Silvestri, Enzo; Sconfienza, Luca Maria

    2016-01-01

    Ultrasound is an established modality for shoulder evaluation, being accurate, low cost and radiation free. Different pathological conditions can be diagnosed using ultrasound and can be treated using ultrasound guidance, such as degenerative, traumatic or inflammatory diseases. Subacromial-subdeltoid bursitis is the most common finding on ultrasound evaluation for painful shoulder. Therapeutic injections of corticosteroids are helpful to reduce inflammation and pain. Calcific tendinopathy of rotator cuff affects up to 20% of painful shoulders. Ultrasound-guided treatment may be performed with both single- and double-needle approach. Calcific enthesopathy, a peculiar form of degenerative tendinopathy, is a common and mostly asymptomatic ultrasound finding; dry needling has been proposed in symptomatic patients. An alternative is represented by autologous platelet-rich plasma injections. Intra-articular injections of the shoulder can be performed in the treatment of a variety of inflammatory and degenerative diseases with corticosteroids or hyaluronic acid respectively. Steroid injections around the long head of the biceps brachii tendon are indicated in patients with biceps tendinopathy, reducing pain and humeral tenderness. The most common indication for acromion-clavicular joint injection is degenerative osteoarthritis, with ultrasound representing a useful tool in localizing the joint space and properly injecting various types of drugs (steroids, lidocaine or hyaluronic acid). Suprascapular nerve block is an approved treatment for chronic shoulder pain non-responsive to conventional treatments as well as candidate patients for shoulder arthroscopy. This review provides an overview of these different ultrasonography-guided procedures that can be performed around the shoulder. PMID:26313499

  2. Adapting Assessment Procedures for Delivery via an Automated Format.

    Science.gov (United States)

    Kelly, Karen L.; And Others

    The Office of Personnel Management (OPM) decided to explore alternative examining procedures for positions covered by the Administrative Careers with America (ACWA) examination. One requirement for new procedures was that they be automated for use with OPM's recently developed Microcomputer Assisted Rating System (MARS), a highly efficient system…

  3. 17 CFR 12.18 - Answer; election of procedure.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Answer; election of procedure...; election of procedure. An answer filed pursuant to § 12.16 of these rules shall meet the following... wishes to pursue under § 12.19 of these rules; (7) An election of an alternative decisional...

  4. Considerations and Recommendations for the Introduction of Objective Performance Criteria for Transcatheter Aortic Heart Valve Device Approval.

    Science.gov (United States)

    Head, Stuart J; Mylotte, Darren; Mack, Michael J; Piazza, Nicolo; van Mieghem, Nicolas M; Leon, Martin B; Kappetein, A Pieter; Holmes, David R

    2016-05-24

    In the United States, new surgical heart valves can be approved on the basis of objective performance criteria (OPC). In contrast, the US Food and Drug Administration traditionally requires stricter criteria for transcatheter heart valve (THV) approval, including randomized, clinical trials. Recent US Food and Drug Administration approval of new-generation THVs based on single-arm studies has generated interest in alternative study approaches for THV device approval. This review evaluates whether THV device approval could follow a pathway analogous to that of surgical heart valves by incorporating OPC and provides several considerations and recommendations. Factors to be taken into account in the construction of OPC include the maturity of THV technology, variability in transcatheter aortic valve replacement practice, end points included as OPC, follow-up terms for specific OPC, patient populations to which these OPC apply, and (statistical) methods for OPC development. We recommend that approval of THV devices in the United States for low- and intermediate-risk patients or for new indications should provisionally rely on data from randomized, clinical trials. However, it is recommended that formal OPC be applied for approval of new-generation THVs for use in high- and extreme-risk patient populations. PMID:27217434

  5. Seal design alternatives study

    International Nuclear Information System (INIS)

    This report presents the results from a study of various sealing alternatives for the WIPP sealing system. Overall, the sealing system has the purpose of reducing to the extent possible the potential for fluids (either gas or liquid) from entering or leaving the repository. The sealing system is divided into three subsystems: drift and panel seals within the repository horizon, shaft seals in each of the four shafts, and borehole seals. Alternatives to the baseline configuration for the WIPP seal system design included evaluating different geometries and schedules for seal component installations and the use of different materials for seal components. Order-of-magnitude costs for the various alternatives were prepared as part of the study. Firm recommendations are not presented, but the advantages and disadvantages of the alternatives are discussed. Technical information deficiencies are identified and studies are outlined which can provide required information

  6. Seal design alternatives study

    Energy Technology Data Exchange (ETDEWEB)

    Van Sambeek, L.L. [RE/SPEC Inc., Rapid City, SD (US); Luo, D.D.; Lin, M.S.; Ostrowski, W.; Oyenuga, D. [Parsons Brinckerhoff Quade & Douglas, Inc., San Francisco, CA (US)

    1993-06-01

    This report presents the results from a study of various sealing alternatives for the WIPP sealing system. Overall, the sealing system has the purpose of reducing to the extent possible the potential for fluids (either gas or liquid) from entering or leaving the repository. The sealing system is divided into three subsystems: drift and panel seals within the repository horizon, shaft seals in each of the four shafts, and borehole seals. Alternatives to the baseline configuration for the WIPP seal system design included evaluating different geometries and schedules for seal component installations and the use of different materials for seal components. Order-of-magnitude costs for the various alternatives were prepared as part of the study. Firm recommendations are not presented, but the advantages and disadvantages of the alternatives are discussed. Technical information deficiencies are identified and studies are outlined which can provide required information.

  7. An alternative currency

    OpenAIRE

    Frendo, Mario; Duca, Edward

    2013-01-01

    Malta- a tiny island, a minute social reality, a precursory canovaccio of European unification- has a unique asset it ought to be prouder of: culture. http://www.um.edu.mt/think/an-alternative-currency/

  8. Alternatives to Nursing Homes

    Science.gov (United States)

    ... this website may not be available. Alternatives to nursing homes Before you make any decisions about long ... live and what help you may need. A nursing home may not be your only choice. Discharge ...

  9. Vaginal dryness alternative treatments

    Science.gov (United States)

    ... a day. Soybeans contain plant-based substances called isoflavones. These substances have an effect on the body ... soy for vasomotor symptoms: the Herbal Alternatives for Menopause (HALT) Study. Menopause . 2008;15(1):51-58. ...

  10. Alternative fuel information sources

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    This short document contains a list of more than 200 US sources of information (Name, address, phone number, and sometimes contact) related to the use of alternative fuels in automobiles and trucks. Electric-powered cars are also included.

  11. General technical approvals for decentralised sustainable urban drainage systems (SUDS) : the current situation in Germany

    OpenAIRE

    Carsten Dierkes; Terry Lucke; Brigitte Helmreich

    2015-01-01

    The use of decentralised, sustainable urban drainage systems (SUDS) for the treatment of stormwater runoff is becoming increasingly prevalent in Germany. Decentralised SUDS can offer a viable and attractive alternative to end of pipe treatment systems for stormwater runoff from urban areas. However, there is still some uncertainty regarding the long-term performance of SUDS, and the general legislative requirements for SUDS approval and testing. Whilst the allowable pollution levels in stormw...

  12. The alternative library

    OpenAIRE

    Collinson, Timothy; A. Williams

    2004-01-01

    Much time and effort has been devoted to designing and developing library Web sites that are easy to navigate by both new students and experienced researchers. In a review of the Southampton Institute Library it was decided that in addition to updating the existing homepage an alternative would be offered. Drawing on theory relating to user interface design, learning styles and creative thinking, an Alternative Library navigation system was added to the more traditional library homepage. The ...

  13. Alternative fuel cycles

    International Nuclear Information System (INIS)

    Uranium resource utilization and economic considerations provide incentives to study alternative fuel cycles as future options to the PHWR natural uranium cycle. Preliminary studies to define the most favourable alternatives and their possible introduction dates are discussed. The important and uncertain components which influence option selection are reviewed, including nuclear capacity growth, uranium availability and demand, economic potential, and required technological developments. Finally, a summary of Ontario Hydro's program to further assess cycle selection and define development needs is given. (auth)

  14. Ultimacy and alternative possibilities

    OpenAIRE

    Fischer, John Martin

    2009-01-01

    I explore a key feature of Robert Kane’s libertarianism (about which I have been puzzled for some time). Kane claims that we should separate issues of alternative possibilities from issues of ultimacy, but he further argues that they are connected in a certain way. I call into question this connection, and I continue to argue for a strict separation of considerations pertaining to alternative possibilities and “actual-sequence” considerations.

  15. Des divisions aux alternances

    Directory of Open Access Journals (Sweden)

    Eric Clemens

    2012-12-01

    Full Text Available - From the divisions to the alternations - Society, action and common good give sense to democracy. Society is in fact a set of unmitigated divisions (horizontal and vertical, material and symbolic. Democratic action, since the discourse’s conflicts, doesn’t change the human beings, but things between they, in the alternation of power’s institutions for our only good in common: the body. With this aim, the Basic Income Earth Network is necessary.

  16. 30 CFR 204.207 - Who will approve, deny, or modify my request for accounting and auditing relief?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Who will approve, deny, or modify my request for accounting and auditing relief? 204.207 Section 204.207 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT ALTERNATIVES FOR MARGINAL PROPERTIES Accounting and Auditing Relief § 204.207 Who...

  17. Doctors Look for Liver Transplant Alternatives

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    @@ Robert Pennington, a 19 - year - old boy, suffers from liver disease. His name was put on a transplant waiting list, but no livers were available. Then Dr. Marlon Levy, a transplant surgeon at Baylor University Medical Center, offered an alternative: a procedure2 using a dead pig's liver. But not a liver from an ordinary pig, "They're genetically modified3 to try to prevent a reaction between the human blood and the pig liver" , Levy said.

  18. 27 CFR 40.394 - Notice of approval of bond.

    Science.gov (United States)

    2010-04-01

    ... manufacturer, in writing, of the bond approval, in order that the manufacturer may commence operations. (72... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Notice of approval of bond... Manufacturers § 40.394 Notice of approval of bond. If the bond required under this subpart is approved by...

  19. 45 CFR 2400.42 - Approval of Plan of Study.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Approval of Plan of Study. 2400.42 Section 2400.42... FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Graduate Study § 2400.42 Approval of Plan of Study. The Foundation must approve each Fellow's Plan of Study. To be approved, the plan must: (a) On a part-time or...

  20. 46 CFR 160.023-4 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.023-4 Section 160.023... Signals § 160.023-4 Approval and production tests. (a) Approval tests. The approval tests are those tests... independent laboratory accepted by the Commandant under § 159.010 of this chapter. (b) Production...

  1. 30 CFR 14.10 - Post-approval product audit.

    Science.gov (United States)

    2010-07-01

    ... to audit for cause at any time MSHA believes the approval holder product is not in compliance with... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Post-approval product audit. 14.10 Section 14... General Provisions § 14.10 Post-approval product audit. (a) Approved conveyor belts will be subject...

  2. 7 CFR 1726.36 - Documents subject to RUS approval.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Documents subject to RUS approval. 1726.36 Section... subject to RUS approval. Unless otherwise indicated, the borrower shall make all contracts and amendments that are subject to RUS approval effective only upon RUS approval....

  3. Civil Procedure In Denmark

    DEFF Research Database (Denmark)

    Werlauff, Erik

    The book contains an up-to-date survey of Danish civil procedure after the profound Danish procedural reforms in 2007. It deals with questions concerning competence and function of Danish courts, commencement and preparation of civil cases, questions of evidence and burden of proof, international...... procedural questions, including relations to the Brussels I Regulation and Denmark's participation in this Regulation via a parallel convention with the EU countries, impact on Danish civil procedure of the convention on human rights, preparation and pronouncement of judgment and verdict, questions of appeal...... scientific activities conducted by the author, partly based on the author's experience as a member, through a number of years, of the Danish Standing Committee on Procedural Law (Retsplejeraadet), which on a continuous basis evaluates the need for civil procedural reforms in Denmark, and finally also based...

  4. Official approval of plans for the ultimate storage of radioactive waste

    International Nuclear Information System (INIS)

    The author presents a detailed review of fundamental requirements of plan approval under atomic energy law in relation to the permits to be issued for the exploratory work at the Gorleben salt mine. The aspects discussed comprise: Acceptability in terms of law of the matter under review, material requirements, definition and approval of procedural steps - probably similar to the practice adopted for part-permits given for nuclear power plants. As regards the Gorleben exploratory activities, a plan approval procedure as set by section 9, subsection (1) Atomic Energy Act is not necessary since the goals of said activities do not include or inevitably entail the erection of the storage facilities. Even if this opinion is not accepted, the author says, the planned work will nevertheless not require a first part-approval under atomic energy law, or under constitutional law. What is indeed required is a permit under mining law and other, related laws governing licenses in the field of public law. (HSCH)

  5. Automating Supplier Selection Procedures

    OpenAIRE

    Davidrajuh, Reggie

    2001-01-01

    This dissertation describes a methodology, tools, and implementation techniques of automating supplier selection procedures of a small and medium-sized agile virtual enterprise. Firstly, a modeling approach is devised that can be used to model the supplier selection procedures of an enterprise. This modeling approach divides the supplier selection procedures broadly into three stages, the pre-selection, selection, and post-selection stages. Secondly, a methodology is presented for automating ...

  6. Pyroshock prediction procedures

    Science.gov (United States)

    Piersol, Allan G.

    2002-05-01

    Given sufficient effort, pyroshock loads can be predicted by direct analytical procedures using Hydrocodes that analytically model the details of the pyrotechnic explosion and its interaction with adjacent structures, including nonlinear effects. However, it is more common to predict pyroshock environments using empirical procedures based upon extensive studies of past pyroshock data. Various empirical pyroshock prediction procedures are discussed, including those developed by the Jet Propulsion Laboratory, Lockheed-Martin, and Boeing.

  7. Judicial civil procedure dragging out in Kosovo

    Directory of Open Access Journals (Sweden)

    Rrustem Qehaja

    2016-03-01

    Full Text Available This article tends to deal with one of the most worrying issues in the judicial system of Kosovo the problem of judicial civil procedure dragging out. The article analyses the reasons of these dragging outs of the judicial civil procedure focusing on the context of one of the basic procedural principles in civil procedure-the principle of economy or efficiency in the courts. Dragging out of civil procedure in Kosovo has put in question not only the basic principles of civil procedure, but it also challenges the general principles related to human rights and freedoms sanctioned not only by the highest legal act of the country, but also with international treaties. The article tends to give a reflection to the most important reasons that effect and influence in these dragging outs of civil procedure, as well as, at the same time aims to give the necessary alternatives to pass through them by identifying dilemmas within the judicial practice. As a result, the motives of this scientific paper are exactly focused at the same time on identifying the dilemmas, as well as presenting ideas, to overstep them, including the judicial practice of the European Court of Human Rights on Article 6 of the European Convention on Human Rights, by which it is given the possibility to offering people efficient and within a reasonable time legal protection of their rights before national courts. For these reasons, the paper elaborates this issue based on both, the legal theory and judicial practice.

  8. 30 CFR 28.25 - Changes or modifications of approved fuses; issuance of modification of certificate of approval.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Changes or modifications of approved fuses... HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR... Approval and Disapproval § 28.25 Changes or modifications of approved fuses; issuance of modification...

  9. Recent New Drug Approvals. Part 1: Drugs with Pediatric Indications

    OpenAIRE

    Shelton, Chasity M.; Chhim, Rebecca F.; Christensen, Michael L.

    2012-01-01

    This two-part review provides information about drugs that have been recently approved by the Food and Drug Administration and focuses on drugs approved with pediatric indications or approved in adults with active pediatric studies. Information was obtained from the product labeling and selected published studies. Part 1 reviews recently approved drugs with labeled pediatric indications, and Part 2 will review recent drug approvals in adults that have potential use in pediatrics and have acti...

  10. Alternative fuels for vehicles; Alternative drivmidler

    Energy Technology Data Exchange (ETDEWEB)

    2012-02-15

    Up until 2020 and onwards the analysis indicates that especially electricity, biogas and natural gas as propellants is economically attractive compared to conventional gasoline and diesel while other fuels have the same or higher costs for petrol and diesel. Especially biogas and electricity will also offer significant reductions in CO{sub 2} emissions, but also hydrogen, methanol, DME and to a lesser extent the second generation bioethanol and most of the other alternative fuels reduce CO{sub 2} emissions. Use of the traditional food-based first generation biofuels involves, at best, only modest climate benefits if land use changes are counted, and at worst, significant negative climate effects. Natural gas as a propellant involves a moderate climate gain, but may play a role for building infrastructure and market for gaseous fuels in large fleets, thereby contributing to the phasing in of biogas for transport. The electric-based automotive fuels are the most effective due to a high efficiency of the engine and an increasing proportion of wind energy in the electricity supply. The methanol track also has a relatively high efficiency. Among the others, the track based on diesel engines (biodiesel) is more effective than the track based on gasoline/Otto engines (gas and ethanol) as a result of the diesel engine's better efficiency. For the heavy vehicles all the selected alternative fuels to varying degrees reduce emissions of CO{sub 2}, particularly DME based on wood. The only exception to this is - as for passenger cars - the propellant synthetic diesel based on coal. (LN).

  11. Alternative reconstruction after pancreaticoduodenectomy

    Directory of Open Access Journals (Sweden)

    Cooperman Avram M

    2008-01-01

    Full Text Available Abstract Background Pancreaticoduodenectomy is the procedure of choice for tumors of the head of the pancreas and periampulla. Despite advances in surgical technique and postoperative care, the procedure continues to carry a high morbidity rate. One of the most common morbidities is delayed gastric emptying with rates of 15%–40%. Following two prolonged cases of delayed gastric emptying, we altered our reconstruction to avoid this complication altogether. Subsequently, our patients underwent a classic pancreaticoduodenectomy with an undivided Roux-en-Y technique for reconstruction. Methods We reviewed the charts of our last 13 Whipple procedures evaluating them for complications, specifically delayed gastric emptying. We compared the outcomes of those patients to a control group of 15 patients who underwent the Whipple procedure with standard reconstruction. Results No instances of delayed gastric emptying occurred in patients who underwent an undivided Roux-en-Y technique for reconstruction. There was 1 wound infection (8%, 1 instance of pneumonia (8%, and 1 instance of bleeding from the gastrojejunal staple line (8%. There was no operative mortality. Conclusion Use of the undivided Roux-en-Y technique for reconstruction following the Whipple procedure may decrease the incidence of delayed gastric emptying. In addition, it has the added benefit of eliminating bile reflux gastritis. Future randomized control trials are recommended to further evaluate the efficacy of the procedure.

  12. Procedural Learning and Dyslexia

    Science.gov (United States)

    Nicolson, R. I.; Fawcett, A. J.; Brookes, R. L.; Needle, J.

    2010-01-01

    Three major "neural systems", specialized for different types of information processing, are the sensory, declarative, and procedural systems. It has been proposed ("Trends Neurosci.",30(4), 135-141) that dyslexia may be attributable to impaired function in the procedural system together with intact declarative function. We provide a brief…

  13. Coombs' Type Response Procedures.

    Science.gov (United States)

    Koehler, Roger A.

    This paper provides substantial evidence in favor of the continued use of conventional objective testing procedures in lieu of either the Coombs' cross-out technique or the Dressel and Schmid free-choice response procedure. From the studies presented in this paper, the tendency is for the cross-out and the free choice methods to yield a decrement…

  14. 7 CFR 1726.252 - Prior approved contract modification related to liability for special and consequential damages.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Prior approved contract modification related to... Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Modifications to RUS Standard Contract Forms § 1726.252 Prior...

  15. 77 FR 65200 - Information Collection Request Sent to the Office of Management and Budget (OMB) for Approval...

    Science.gov (United States)

    2012-10-25

    ... and Threatened Wildlife (delisted) on August 8, 2007 (72 FR 37346, July 9, 2007). Section 4(g) of the... (OMB) for Approval; Bald Eagle Post-delisting Monitoring AGENCY: Fish and Wildlife Service, Interior... to develop plans and procedures for systematically monitoring recovered wildlife and plants after...

  16. 78 FR 55057 - Authority To Manufacture Carbon Fiber for the U.S. Market Not Approved; Foreign-Trade Subzone...

    Science.gov (United States)

    2013-09-09

    ... Foreign-Trade Zones Board Authority To Manufacture Carbon Fiber for the U.S. Market Not Approved; Foreign... manufacture carbon fiber under zone procedures for the U.S. market within Subzone 148C at the TTA facility in... comment has been given in the Federal Register (75 FR 61696, 10/6/2010; 75 FR 74002, 11/30/2010; 77...

  17. Catalysis for alternative energy generation

    CERN Document Server

    2012-01-01

    Summarizes recent problems in using catalysts in alternative energy generation and proposes novel solutions  Reconsiders the role of catalysis in alternative energy generation  Contributors include catalysis and alternative energy experts from across the globe

  18. Reforming Russian Civil Procedur

    Directory of Open Access Journals (Sweden)

    Dmitry Maleshin

    2016-03-01

    Full Text Available The II Annual Symposium of the journal Herald of Civil Procedure ‘2015: The Civil Procedure 2.0: Reform and Current State’ took place on October 9, 2015, at the Faculty of Law of Kazan (Volga region Federal University.The Symposium is now an established tradition for the University. In 2015 it brought together in Kazan eminent scholars of civil procedure from cities across the whole of Russia: Moscow, St. Petersburg, Saratov, Ekaterinburg, Omsk, Samara, Nizhnekamsk and others. This large-scale event attracted the attention not only of Russian scholars, but also of legal scholars from abroad: Elisabetta Silvestri (Professor, University of Pavia, Italy, William B. Simons (Professor, University of Tartu, Estonia, Jaroslav Turlukovsky (Professor, Warsaw University, Poland, Stuart H. Schultz (Practising Attorney, USA, Irina Izarova (Associate Professor, Taras Shevchenko National University of Kyiv, Ukraine.The opening ceremony of the Symposium began with greetings to all participants and best wishes for productive discussions. Participants were welcomed with remarks by Marat Khairullin, Deputy Chair of the Supreme Court of the Republic of Tatarstan, Radik Ilyasov, Head of the Federal Bailiff Service of the Republic of Tatarstan, and Ildar Tarkhanov, Academic Supervisor at the Faculty of Law. They expressed their appreciation for the great value of the journal Herald of Civil Procedure in the growth of the science of civil procedure and enforcement procedure, and for its contributions to the development of the judicial system of the Russian Federation.In addition to hearing prepared reports and discussing viewpoints on current issues of civil and arbitration procedure, participants attended presentations by representatives from procedural law periodicals in the frame of the Symposium. The Editor-in-Chief of Herald of Civil Procedure, Damir Valeev, and the Commercial Director of the Statut Publishing House (Moscow, Kirill Samoilov, presented new

  19. Alternatives for pseudofinite groups

    CERN Document Server

    Houcine, Abderezak Ould

    2012-01-01

    The famous Tits' alternative states that a linear group either contains a nonabelian free group or is soluble-by-(locally finite). We study in this paper similar alternatives in pseudofinite groups. We show for instance that an $\\aleph_{0}$-saturated pseudofinite group either contains a subsemigroup of rank $2$ or is nilpotent-by-(uniformly locally finite). We call a class of finite groups $G$ weakly of bounded rank if the radical $rad(G)$ has a bounded Pr\\"ufer rank and the index of the sockel of $G/rad(G)$ is bounded. We show that an $\\aleph_{0}$-saturated pseudo-(finite weakly of bounded rank) group either contains a nonabelian free group or is nilpotent-by-abelian-by-(uniformly locally finite). We also obtain some relations between this kind of alternatives and amenability.

  20. A Randomized Procedure for Choosing Data Transformation

    OpenAIRE

    Valentina Corradi; Swanson, Norman R.

    2001-01-01

    Standard unit root and stationarity tests (see e.g. Dickey and Fuller (1979)) assume linearity under both the null and the alternative hypothesis. Violation of this linearity assumption can result in severe size and power distortion, both in finite and large samples. Thus, it is reasonable to address the problem of data transformation before running a unit root test. In this paper we propose a simple randomized procedure, coupled with sample conditioning, for choosing between levels and log-l...

  1. Field theory hamiltonization as a twofold procedure

    International Nuclear Information System (INIS)

    A field theory hamiltonization procedure valid for both linear (on φt) and non-linear Lagrangians is proposed. It is shown that usual hamiltonian formulation is based on an envelope solution of a partial differential equation. The choice of the complete solution of the same equation leads to an alternative hamiltonian description of the same field and is the only open possibility for linear Lagrangian systems. (author)

  2. Toddler test or procedure preparation

    Science.gov (United States)

    Preparing toddler for test/procedure; Test/procedure preparation - toddler; Preparing for a medical test or procedure - toddler ... about the procedure to 5 or 10 minutes. Toddlers have a short attention span. Any preparation should ...

  3. Bouncing alternatives to inflation

    CERN Document Server

    Lilley, Marc

    2015-01-01

    Although the inflationary paradigm is the most widely accepted explanation for the current cosmological observations, it does not necessarily correspond to what actually happened in the early stages of our Universe. To decide on this issue, two paths can be followed: first, all the possible predictions it makes must be derived thoroughly and compared with available data, and second, all imaginable alternatives must be ruled out. Leaving the first task to all other contributors of this volume, we concentrate here on the second option, focusing on the bouncing alternatives and their consequences.

  4. Renewable and alternative energy

    CERN Document Server

    Curley, Robert

    2011-01-01

    With growing populations across the world consuming Earth's limited oil and natural gas reserves, the environmental and economic toll of energy dependence becomes an increasingly global concern. The development of renewable forms of energy-solar, wind, water, and geothermal, to name a few-offers alternatives to fossil fuels. Consumers are embracing these new modes of energy delivery and use. This extensive volume examines the possibility of a cleaner and more energy efficient future by detailing the historic and emerging technologies behind some the most promising alternative resources.

  5. Domestic energy alternatives

    International Nuclear Information System (INIS)

    These alternatives include biomass, clean coal, geothermal, hydropower, natural gas, nuclear, solar and photovoltaic, and wind. With the current, volatile situation in the Middle East, this nation's political leaders appear to be left scratching their heads in their attempts to come up with new, sound, energy policies to reduce our dependence on foreign oil. Therefore, the FORTNIGHTLY's editorial staff thought that this might be an opportune time to briefly examine some home-grown and environmentally responsible fuel alternatives to black gold. While some of these electricity-producing technologies are still on the horizon, others are available now

  6. 46 CFR 502.411 - Mediation and other alternative means of dispute resolution.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Mediation and other alternative means of dispute... PROVISIONS RULES OF PRACTICE AND PROCEDURE Alternative Dispute Resolution § 502.411 Mediation and other alternative means of dispute resolution. (a) Parties are encouraged to utilize mediation or other forms...

  7. Review of non-FDA-approved fillers.

    Science.gov (United States)

    Ellis, David A F; Segall, Lorne

    2007-05-01

    The number of commercially available injectable soft tissue fillers has increased dramatically worldwide over the past decade. In the United States, a variety of temporary non-collagen-based fillers have been approved. However, no permanent soft tissue injectable fillers are currently approved by the US Food and Drug Administration. This article discusses some of the more popular soft tissue fillers, such as Restylane Fine Line, Restylane SQ, Perlane, Artecoll, Dermalive, Dermadeep, Bioalcamid, Bioplastique, Evolution, Outline, Argiform, and Aquamid, which are all available outside of the United States. PMID:17544940

  8. Reformation of Tax Procedures along the European Integration Process

    OpenAIRE

    Genta Bungo-Tafa

    2012-01-01

    Approximation of the Albanian legislation with the acquis communautaire is accompanied by deep reforms and, consequently, by reforms of relations accompanying the relevant laws. In this context, one of the European Union recommendations for the Albanian government was the country’s tax reform. This reform was accompanied by the abrogation of Law no 8560, of 22 December 1999 “On Tax Procedures in the Republic of Albania” and the approval of the new Law No. 9920, of 19 May 2008 “On Tax Procedur...

  9. Costing imaging procedures

    Energy Technology Data Exchange (ETDEWEB)

    Bretland, P.M.

    1988-01-01

    A method of costing using a computer system with 512 Kb of memory has been devised, classifying costs into variable, semi-variable and fixed and using the principle of overhead absorption for expenditure not readily allocated to individual procedures. A cost spectrum for 1984-5 was established. Cheapest examinations were plain radiographs outside normal working hours, followed by plain radiographs, ultrasound, special procedures, fluoroscopy, nuclear medicine, angiography and angiographic interventional procedures in normal working hours, differing from some published figures, particularly those in the Koerner report. There was some overlap between fluoroscopic interventional and the cheaper nuclear medicine procedures, and between some of the more expensive nuclear medicine procedures and the cheaper angiographic ones. Only angiographic and the few more expensive nuclear medicine procedures exceed the cost of the in-patient day. Total cost of the imaging service to the district was approx. 4% of total hospital expenditure. It is shown that where more procedures are undertaken, the semi-variable and fixed (including capital) elements of the cost decrease (and vice versa).

  10. Constructing a composite indicator with multiplicative aggregation under the objective of ranking alternatives

    OpenAIRE

    F J Blancas; Contreras, I; J M Ramírez-Hurtado

    2013-01-01

    Composite indicators (CIs), constructed on the basis of the ‘benefit of the doubt’ criterion, are characterized by endogenously determined vectors of weights. In this paper, a new procedure to construct CIs is proposed in an attempt to overcome the main weakness of this family of procedures: the determination of an individual weighting vector for each alternative, which makes comparisons between alternatives difficult and the existence of multiple ties. A new procedure is proposed which, whil...

  11. Compensated pulsed alternator

    International Nuclear Information System (INIS)

    This invention relates to an electromechanical energy converter with inertial energy storage. The device, a single phase, two or multi-pole alternator with stationary field coils, and a rotating armature is provided. The rotor itself may be of laminated steel for slower pulses or for faster pulses should be nonmagnetic and electrically nonconductive in order to allow rapid penetration of the field as the armature coil rotates. The armature coil comprises a plurality of power generating conductors mounted on the rotor. The alternator may also include a stationary or counterrotating compensating coil to increase the output voltage thereof and to reduce the internal impedance of the alternator at the moment of peak output. As the machine voltage rises sinusoidally, an external trigger switch is adapted to be closed at the appropriate time to create the desired output current from said alternator to an external load circuit, and as the output current passes through zero a self-commutating effect is provided to allow the switch to disconnect the generator from the external circuit

  12. Alternatives to Violence.

    Science.gov (United States)

    Children Today, 1994

    1994-01-01

    Notes that our capacity to diffuse conflict rests in our ability to recognize and verbalize feelings, develop empathy, and think of alternatives to violence. Explores the influence of role models and culture on violence and how the media can use violent images effectively in helping us confront a culture of violence. (HTH)

  13. Tracking alternative energy sources

    International Nuclear Information System (INIS)

    This is the third and last article dealing with global energy topics analyzed at the 13th World Energy Congress. The varied particality or applicability of the following alternative energy sources is briefly discussed at a popular level: fusion, solar, ocean thermal energy conversion, waves, winds, tidal, and geothermal

  14. Alternatives to Blood Transfusion

    Science.gov (United States)

    ... saved articles window. My Saved Articles » My ACS » Blood Transfusion and Donation + - Text Size Download Printable Version [PDF] » TOPICS Document ... Possible risks of blood transfusions Alternatives to blood transfusions Donating blood Blood donation by cancer survivors To learn more References Previous ...

  15. Alternative health insurance schemes

    DEFF Research Database (Denmark)

    Keiding, Hans; Hansen, Bodil O.

    2002-01-01

    In this paper, we present a simple model of health insurance with asymmetric information, where we compare two alternative ways of organizing the insurance market. Either as a competitive insurance market, where some risks remain uninsured, or as a compulsory scheme, where however, the level...

  16. TWTF design alternates

    International Nuclear Information System (INIS)

    The Transuranic Waste Treatment Facility (TWTF) will process transuranic (TRU) waste in retrievable storage at the Idaho National Engineering Laboratory (INEL). The costs for a TWTF concept using a slagging pyrolysis incinerator were excessive. Alternate concepts using a slow speed shredder, a rotary kiln incinerator, and concrete immobilization should result in significant cost reductions. These will be included in future TWTF considerations

  17. Alternative and Integrative Medicine

    Science.gov (United States)

    ... are the healthcare rituals practiced by a given culture (eg, Asian, Indian, African). Homeopathic Medicine: This alternative medicine system is based on the principle that “like cures like.” In other words, the same substance ... American Brain Tumor Association 8550 W. Bryn Mawr Ave. ...

  18. Alternative calcination development status report

    International Nuclear Information System (INIS)

    The Programmatic Spent Nuclear Fuel and (INEEL) Environmental Restoration and Waste Management Programs Environmental Impact Statement Record of Decision, dated June 1, 1995, specifies that high-level waste stored in the underground tanks at the ICPP continue to be calcined while other options to treat the waste are studied. Therefore, the High-Level Waste Program has funded a program to develop new flowsheets to increase the liquid waste processing rate. Simultaneously, a radionuclide separation process, as well as other options, are also being developed, which will be compared to the calcination treatment option. Two alternatives emerged as viable candidates; (1) elevated temperature calcination (also referred to as high temperature calcination), and (2) sugar-additive calcination. Both alternatives were determined to be viable through testing performed in a lab-scale calcination mockup. Subsequently, 10-cm Calciner Pilot Plant scoping tests were successfully completed for both flowsheets. The results were compared to the standard 500 C, high-ANN flow sheet (baseline flowsheet). The product and effluent streams were characterized to help elucidate the process chemistry and to investigate potential environmental permitting issues. Several supplementary tests were conducted to gain a better understanding of fine-particles generation, calcine hydration, scrub foaming, feed makeup procedures, sugar/organic elimination, and safety-related issues. Many of the experiments are only considered to be scoping tests, and follow-up experiments will be required to establish a more definitive understanding of the flowsheets. However, the combined results support the general conclusion that flowsheet improvements for the NWCF are technically viable

  19. Procedures for Sampling Vegetation

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report outlines vegetation sampling procedures used on various refuges in Region 3. The importance of sampling the response of marsh vegetation to management...

  20. Tests and Procedures

    Science.gov (United States)

    ... procedure is being done. How the results will influence treatment. What your child will experience during the ... Understanding Children’s Cancer About Cancer What is Cancer? Childhood Cancer Statistics Childhood Cancer Statistics Overview Number of ...

  1. Cosmetic Procedure Questions

    Science.gov (United States)

    ... How to Choose the Best Skin Care Products Cosmetic Procedure Questions Want to look younger? Start by ... fillers, neuromodulators (Botox) and hair restoration among others. Cosmetic Questionnaire Print out this PDF version to take ...

  2. IC Treatment: Surgical Procedures

    Science.gov (United States)

    ... surgeon fashions a tube or conduit from a short section of bowel and places the ureters (which carry urine from ... this procedure, some patients will continue to experience symptoms of ... augmented bowel segment of these newly fashioned bladders. Some patients ...

  3. Anxiety Around Medical Procedures

    Science.gov (United States)

    ... Kidney/Wilms Tumor Liver Cancer Lymphoma (Non-Hodgkin) Lymphoma (Hodgkin) Neuroblastoma Osteosarcoma Retinoblastoma Rhabdomyosarcoma Skin Cancer Soft Tissue Sarcoma Thyroid Cancer Understanding Children's Cancer Anxiety Around Procedures Childhood Cancer Statistics Late ...

  4. Costing imaging procedures.

    Science.gov (United States)

    Bretland, P M

    1988-01-01

    The existing National Health Service financial system makes comprehensive costing of any service very difficult. A method of costing using modern commercial methods has been devised, classifying costs into variable, semi-variable and fixed and using the principle of overhead absorption for expenditure not readily allocated to individual procedures. It proved possible to establish a cost spectrum over the financial year 1984-85. The cheapest examinations were plain radiographs outside normal working hours, followed by plain radiographs, ultrasound, special procedures, fluoroscopy, nuclear medicine, angiography and angiographic interventional procedures in normal working hours. This differs from some published figures, particularly those in the Körner report. There was some overlap between fluoroscopic interventional and the cheaper nuclear medicine procedures, and between some of the more expensive nuclear medicine procedures and the cheaper angiographic ones. Only angiographic and the few more expensive nuclear medicine procedures exceed the cost of the inpatient day. The total cost of the imaging service to the district was about 4% of total hospital expenditure. It is shown that where more procedures are undertaken, the semi-variable and fixed (including capital) elements of the cost decrease (and vice versa) so that careful study is required to assess the value of proposed economies. The method is initially time-consuming and requires a computer system with 512 Kb of memory, but once the basic costing system is established in a department, detailed financial monitoring should become practicable. The necessity for a standard comprehensive costing procedure of this nature, based on sound cost accounting principles, appears inescapable, particularly in view of its potential application to management budgeting. PMID:3349241

  5. 40 CFR 52.722 - Approval status.

    Science.gov (United States)

    2010-07-01

    ... Air Act, as amended in 1977. (c) The Administrator finds that the carbon monoxide control strategy... National Ambient Air Quality Standards under section 110 of the Clean Air Act. Furthermore, the... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL...

  6. 40 CFR 52.2522 - Approval status.

    Science.gov (United States)

    2010-07-01

    ... provisions do not meet the requirements of 40 CFR 51.160 for scope. EPA also disapproves 45 CSR 13 section 9... the West Virginia SIP. These provisions do not meet the requirements of 40 CFR 51.161 for public... attainment of the primary SO2 NAAQS. The Administrator does not approve the State's control strategy...

  7. 7 CFR 1735.61 - Approval criteria.

    Science.gov (United States)

    2010-01-01

    ... of its mortgage or loan contract to obtain RUS approval of a merger or acquisition, the borrower...) Whether the merger or acquisition may result in any relinquishment, impairment, or waiver of a right or power of the Government; (3) Whether the proposed merger or acquisition is in the best interests of...

  8. The Ethics and Politics of Ethics Approval

    Science.gov (United States)

    Battin, Tim; Riley, Dan; Avery, Alan

    2014-01-01

    The regulatory scope of Human Research Ethics Committees can be problematic for a variety of reasons. Some scholars have argued the ethics approval process, for example, is antithetical to certain disciplines in the humanities and social sciences, while others are willing to give it qualified support. This article uses a case study to cast the…

  9. 23 CFR 645.215 - Approvals.

    Science.gov (United States)

    2010-04-01

    .... 109, 111, and 116, and 23 CFR 1.23 and 1.27, and meet the requirements of this regulation, the FHWA... Accommodation of Utilities § 645.215 Approvals. (a) Each State transportation department shall submit a... the FHWA for prior concurrence, except when the proposed installation is not in accordance with...

  10. 77 FR 16544 - Pesticide Product Registration Approvals

    Science.gov (United States)

    2012-03-21

    ... of receipt published on April 14, 2010 (75 FR 19388; FRL- 8808-5). One comment was received during... AGENCY Pesticide Product Registration Approvals AGENCY: Environmental Protection Agency (EPA). ACTION... pesticide products and amended registrations for currently existing pesticide products. FOR...

  11. Side effects of cytokines approved for therapy.

    Science.gov (United States)

    Baldo, Brian A

    2014-11-01

    Cytokines, currently known to be more than 130 in number, are small MW (aldesleukin (rhIL-2), oprelvekin (rhIL-11), filgrastim and tbo-filgrastim (rhG-CSF), sargramostim (rhGM-CSF), metreleptin (rh-leptin) and the rh-erythropoietins, epoetin and darbepoietin alfa. Anakinra, a recombinant receptor antagonist for IL-1, is in the IL-1 family; recombinant interferons alfa-1, alfa-2, beta-1 and gamma-1 make up the interferon family; palifermin (rhKGF) and becaplermin (rhPDGF) are in the PDGF family; and rhBMP-2 and rhBMP-7 represent the TGFβ family. The main physicochemical features, FDA-approved indications, modes of action and side effects of these approved cytokines are presented. Underlying each adverse events profile is their pleiotropism, potency and capacity to release other cytokines producing cytokine 'cocktails'. Side effects, some serious, occur despite cytokines being endogenous proteins, and this therefore demands caution in attempts to introduce individual members into the clinic. This caution is reflected in the relatively small number of cytokines currently approved by regulatory agencies and by the fact that 14 of the FDA-approved preparations carry warnings, with 10 being black box warnings. PMID:25270293

  12. Reflections on the Ethics-Approval Process

    Science.gov (United States)

    Murray, Lee; Pushor, Debbie; Renihan, Pat

    2012-01-01

    It is sometimes a difficult journey receiving ethics approval for research involving vulnerable populations, research involving our own children, or innovative research methodologies such as autoethnography. This autoethnographical account is a story about one student who wanted to write a PhD dissertation in a very different way and also the…

  13. 46 CFR 58.16-10 - Approvals.

    Science.gov (United States)

    2010-10-01

    ... been involved in a fire. (c) Safety-relief devices. All required safety-relief devices must be approved... in accordance with 49 CFR part 178. (2) All liquefied petroleum gas cylinders in service shall bear a... with 49 CFR part 178. (d) Valves, regulators, and vaporizers. All component parts of the system,...

  14. 78 FR 11174 - Recent Postings of Broadly Applicable Alternative Test Methods

    Science.gov (United States)

    2013-02-15

    ... published at 72 FR 4257 (January 30, 2007) and found on the EPA's Web site at www.epa.gov/ttn/emc/approalt... alternative test methods are outlined at 72 FR 4257 (January 30, 2007). We will continue to announce approvals... questions about this notice, contact Ms. Lula H. Melton, Air Quality Assessment Division, Office of...

  15. Report to the Congress on alternative methods for the Strategic Petroleum Reserve

    Energy Technology Data Exchange (ETDEWEB)

    1990-02-01

    The purpose of this study is to fulfill the requirements of Public Law No. 101-46, approved June 30, 1989. The study describes and evaluates alternative methods for financing the future expansion of the Strategic petroleum Reserve (SPR), both to the current target level of 750 million barrels and to potential future levels of up to one billion barrels.

  16. 76 FR 27987 - Foreign-Trade Zone 216-Olympia, Washington; Application for Reorganization Under Alternative Site...

    Science.gov (United States)

    2011-05-13

    ... zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170, 1/12/09 (correction 74 FR 3987, 1/22/09); 75 FR 71069-71070, 11/22/10). The ASF is an option for grantees for the..., 2011. FTZ 216 was approved by the Board on August 16, 1996 (Board Order 836, 61 FR 45408,...

  17. Trends in global approvals of biotech crops (1992-2014).

    Science.gov (United States)

    Aldemita, Rhodora R; Reaño, Ian Mari E; Solis, Renando O; Hautea, Randy A

    2015-01-01

    With the increasing number of genetically modified (GM) events, traits, and crops that are developed to benefit the global population, approval of these technologies for food, feed, cultivation and import in each country may vary depending on needs, demand and trade interest. ISAAA established a GMO Approval Database to document global approvals of biotech crops. GM event name, crops, traits, developer, year of approval for cultivation, food/feed, import, and relevant dossiers were sourced from credible government regulatory websites and biosafety clearinghouses. This paper investigates the trends in GM approvals for food, feed and cultivation based on the number of approving countries, GM crops, events, and traits in the last 23 y (1992-2014), rationale for approval, factors influencing approvals, and their implications in GM crop adoption. Results show that in 2014, there was an accumulative increase in the number of countries granting approvals at 29 (79% developing countries) for commercial cultivation and 31 (70% developing countries) for food and 19 (80% developing developing) for feed; 2012 had the highest number of approving countries and cultivation approvals; 2011 had the highest number of country approvals for feed, and 2014 for food approvals. Herbicide tolerance trait had the highest events approved, followed by insect tolerance traits. Approvals for food product quality increased in the second decade. Maize had the highest number of events approved (single and stacked traits), and stacked traits product gradually increased which is already 30% of the total trait approvals. These results may indicate understanding and acceptance of countries to enhance regulatory capability to be able to benefit from GM crop commercialization. Hence, the paper provided information on the trends on the growth of the GM crop industry in the last 23 y which may be vital in predicting future GM crops and traits. PMID:26039675

  18. Taylor’s Critique of Procedural Liberalism and Modern Practical Rationality

    OpenAIRE

    Nelson Jair Cuchumbé H.

    2010-01-01

    This article examines Charles Taylor’s critique of the model of procedural liberalism and the modern conception of practical rationality. The starting point is that Taylor’s critique is based on contributions of the substantive philosophical tradition, which makes possible an alternative liberalism project different from procedural liberalism. To prove this point of view, in first place, it presents Taylor’s approach to the debate between alternative liberalism and procedural liberalism. Seco...

  19. [Alternatives to animal testing].

    Science.gov (United States)

    Fabre, Isabelle

    2009-11-01

    The use of alternative methods to animal testing are an integral part of the 3Rs concept (refine, reduce, replace) defined by Russel & Burch in 1959. These approaches include in silico methods (databases and computer models), in vitro physicochemical analysis, biological methods using bacteria or isolated cells, reconstructed enzyme systems, and reconstructed tissues. Emerging "omic" methods used in integrated approaches further help to reduce animal use, while stem cells offer promising approaches to toxicologic and pathophysiologic studies, along with organotypic cultures and bio-artificial organs. Only a few alternative methods can so far be used in stand-alone tests as substitutes for animal testing. The best way to use these methods is to integrate them in tiered testing strategies (ITS), in which animals are only used as a last resort. PMID:20669543

  20. Outlook for alternative transportation fuels

    Energy Technology Data Exchange (ETDEWEB)

    Gushee, D.E. [Univ. of Illinois, Chicago, IL (United States)

    1996-12-31

    This presentation provides a brief review of regulatory issues and Federal programs regarding alternative fuel use in automobiles. A number of U.S. DOE initiatives and studies aimed at increasing alternative fuels are outlined, and tax incentives in effect at the state and Federal levels are discussed. Data on alternative fuel consumption and alternative fuel vehicle use are also presented. Despite mandates, tax incentives, and programs, it is concluded alternative fuels will have minimal market penetration. 7 refs., 5 tabs.

  1. [Alternative endourologic methods for treatment of urethral stricture].

    Science.gov (United States)

    Niesel, T; Moore, R G; Hofmann, R; Kavoussi, L R

    1998-01-01

    Advances in endoscopic instrumentation and techniques offer new alternatives for safe and effective treatment of urethral strictures. Visual internal urethrotomy, the standard treatment modality, is associated with new scar formation with stricture recurrence. This experience has led to the investigation of alternative techniques which would avoid or ameliorate this result. This article reviews the current literature and discusses these newer approaches, including balloon dilatation, laser urethrotomy, endoscopic urethroplasty, "cut to the light" and "core through" procedures, and urethral wallstent implantation. PMID:9540185

  2. Alternatives to animal experimentation for hormonal compounds research

    OpenAIRE

    M. PENZA; Jeremic, M.; Montani, C.; Unkila, M.; L. Caimi; G. Mazzoleni; Di Lorenzo, Diego

    2009-01-01

    Alternatives to animal testing and the identification of reliable methods that may decrease the need for animals are currently the subject of intense investigation worldwide. Alternative testing procedures are particularly important for synthetic and natural chemicals that exert their biological actions through binding nuclear receptors, called nuclear receptors-interacting compounds (NR-ICs), for which research is increasingly emphasizing the limits of several models in the accurate estimati...

  3. A component analysis of "stereotypy as reinforcement" for alternative behavior.

    OpenAIRE

    Hanley, G P; Iwata, B A; Thompson, R H; Lindberg, J S

    2000-01-01

    Results from several studies have suggested that the opportunity to engage in stereotypic behavior may function as reinforcement for alternative, more socially desirable behaviors. However, the procedural components of this intervention include several distinct operations whose effects have not been analyzed separately. While measuring the occurrence of stereotypy and an alternative behavior (manipulation of leisure materials), we exposed 3 participants to three or four components of a "stere...

  4. 30 CFR 28.20 - Certificates of approval; scope of approval.

    Science.gov (United States)

    2010-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT... only for individual, completely fabricated fuses which have been examined, inspected, and tested...

  5. 77 FR 26474 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Approval of 2011 Consent...

    Science.gov (United States)

    2012-05-04

    ... Maryland Department of the Environment (MDE). These revisions approve specific provisions of a 2011 Consent Decree between MDE and GenOn to reduce particulate matter (PM), sulfur oxides (SO X ), and...

  6. 28 CFR 58.16 - Procedures for inclusion on the approved list.

    Science.gov (United States)

    2010-07-01

    ... not limited to, changes in the location of primary or satellite business office(s); the principal contact person; name or fictitious name under which the agency does business; management, including the board of directors; a merger or consolidation with another entity; and the banks or...

  7. 49 CFR 173.56 - New explosives-definition and procedures for classification and approval.

    Science.gov (United States)

    2010-10-01

    ... (ANFO)”, the only test required for classification purposes is the Cap Sensitivity Test—Test Method 5(a... the name and address of the person or organization conducting the test, date of the test,...

  8. Participation of the citizen in the approval procedures for power stations

    International Nuclear Information System (INIS)

    The author first deals with the causes, and the forms taken, of the trend towards more citizen participation. In detail he then deals with the complaint from an association as the most important cause of disagreement in citizen participation; also discussed are the disquiet under constitutional law concerning control of the administration by associations and courts instead of by the government, problems of the law protection system, and practical considerations. Finally he indicates reasonable possibilities of participation by associations, e.g. in relation to the provision of a particular site. (orig.)

  9. 78 FR 16138 - Application Procedures and Criteria for Approval of Nonprofit Budget and Credit Counseling...

    Science.gov (United States)

    2013-03-14

    ... Trustees (``Interim Final Rule''). 71 FR 38,076 (July 5, 2006). Due to the necessity of quickly... FR 6,062, EOUST published a proposed rule on this topic in an effort to maximize public input, rather... Discrimination Affecting Limited English Proficient Persons, 67 FR 41,455 (June 18, 2002). Though the wording...

  10. 48 CFR 3009.171-7 - Contract award approval procedures for contractors with felony convictions.

    Science.gov (United States)

    2010-10-01

    ... felony no longer calls into question the individual or business concern's integrity or business ethics... individual or business concern's integrity or business ethics and that an award would be consistent with the... the subject felony is not a serious felony as defined in (HSAR) 48 CFR 3009.171-5; that...

  11. Alternatives to ECMO.

    OpenAIRE

    Donn, S M

    1994-01-01

    The past decade has witnessed technological advancements which are unparalleled in neonatology. ECMO has been demonstrated to be a powerful rescue treatment, but has perhaps been overutilised and is not universally available. Alternative treatments have been shown to be both safe and efficacious in the management of infants with respiratory failure. Direct head to head clinical trials will probably be necessary to establish appropriate criteria and indications for use, given the wide diversit...

  12. Alternative approaches in IVF

    OpenAIRE

    Fauser, Bart; Bouchard, P.; Coelingh Bennink, H.J.; Collins, John; Devroey, P.; Evers, Johannes; Van Steirteghem, A

    2002-01-01

    textabstractVarious new developments in clinical and basic science which may impact on IVF in the near or distant future will be discussed in this review. These key areas include the regulation of early follicle development and the extended in-vitro culture of oocytes and embryos. Moreover, alternative compounds and ovarian stimulation protocols will be discussed, along with highlights in the development of the cryopreservation of excess oocytes or embryos. Finally, the health economics of IV...

  13. Alternative Dispute Resolution

    OpenAIRE

    Mihaela Irina IONESCU

    2004-01-01

    Alternative dispute resolution (ADR) includes dispute resolution processes and techniques that act as a means for disagreeing parties to come to an agreement short of litigation. It is a collective term for the ways that parties can settle disputes, with (or without) the help of a third party.Despite historic resistance to ADR by many popular parties and their advocates, ADR has gained widespread acceptance among both the general public and the legal profession in recent years. In fact, some ...

  14. Metamaterials critique and alternatives

    CERN Document Server

    Munk, Ben A

    2009-01-01

    A Convincing and Controversial Alternative Explanation of Metamaterials with a Negative Index of Refraction In a book that will generate both support and controversy, one of the world's foremost authorities on periodic structures addresses several of the current fashions in antenna design-most specifically, the popular subject of double negative metamaterials. Professor Munk provides a comprehensive theoretical electromagnetic investigation of the issues and concludes that many of the phenomena claimed by researchers may be impossible. While denying the existence of negative refractio

  15. Alternatives to Higgs scalars

    International Nuclear Information System (INIS)

    We discuss alternatives to the Higgs Scalar doublet Φ of the minimal standard model. In particular we review technicolor (TC) and extended technicolor (ETC), and show that the threat of flavour changing neutral currents (FCNC's) is avoided by walking TC and/or strongly coupled ETC. The phenomenology of minimal TC and the techni-family is discussed. Finally we consider the possibility that the Higgs doublet Φ is a composite bound state of quarks from the third (or fourth) family

  16. Matching bunched beams to alternating gradient focusing systems

    International Nuclear Information System (INIS)

    A numerical procedure for generating phase-space distributions matched to alternating gradient focusing systems has been tested. For a smooth-focusing system a matched distribution can be calculated. With a particle tracing simulation code such a distribution can be followed while adiabatically deforming the focusing forces until an alternating gradient configuration is reached. The distribution remains matched; the final distribution is periodic with the structure period. External nonlinearities, including nonlinear couplings, were included in our examples but space charge was not. This procedure is expected to work with space charge but will require a 3-D space-charge calculation in the simulation code

  17. Proposing an alternative linear a successful example

    International Nuclear Information System (INIS)

    The mandated Sub-Title D landfill liner design which meets the basic Sub-Title D performance requirement (no exceedance of groundwater quality standards at the landfill boundary in 30 years) specifies construction of a two foot thick clay layer with a hydraulic conductivity no greater than 10-7 cm/sec and a 60 mil HDPE membrane. This mandated design is easily accepted by the regulatory community but very difficult and expensive to properly construct. Fundamental problems arise constructing a clay linear that meets the 10-7cm/sec hydraulic conductivity requirement and, in cold climates, protecting the clay but their use requires obtaining special approval for an open-quotes alternative linearclose quotes from the appropriate regulatory agency. This paper presents a simple example of an open-quotes alternative linerclose quotes proposal that has been accepted by the Montana Department of Health and Environmental Sciences for a new landfill. The arguments presented for the use of a GCL combine site-specific parameters with easily understood calculations to demonstrate compliance with the basic Sub-Title D performance requirement. 8 refs., 6 tabs

  18. Alternative Fuels: Research Progress

    Directory of Open Access Journals (Sweden)

    Maher A.R. Sadiq Al-Baghdadi

    2013-01-01

    Full Text Available Chapter 1: Pollutant Emissions and Combustion Characteristics of Biofuels and Biofuel/Diesel Blends in Laminar and Turbulent Gas Jet Flames. R. N. Parthasarathy, S. R. Gollahalli Chapter 2: Sustainable Routes for The Production of Oxygenated High-Energy Density Biofuels from Lignocellulosic Biomass. Juan A. Melero, Jose Iglesias, Gabriel Morales, Marta Paniagua Chapter 3: Optical Investigations of Alternative-Fuel Combustion in an HSDI Diesel Engine. T. Huelser, M. Jakob, G. Gruenefeld, P. Adomeit, S. Pischinger Chapter 4: An Insight into Biodiesel Physico-Chemical Properties and Exhaust Emissions Based on Statistical Elaboration of Experimental Data. Evangelos G. Giakoumis Chapter 5: Biodiesel: A Promising Alternative Energy Resource. A.E. Atabani Chapter 6: Alternative Fuels for Internal Combustion Engines: An Overview of the Current Research. Ahmed A. Taha, Tarek M. Abdel-Salam, Madhu Vellakal Chapter 7: Investigating the Hydrogen-Natural Gas Blends as a Fuel in Internal Combustion Engine. ?lker YILMAZ Chapter 8: Conversion of Bus Diesel Engine into LPG Gaseous Engine; Method and Experiments Validation. M. A. Jemni , G. Kantchev , Z. Driss , R. Saaidia , M. S. Abid Chapter 9: Predicting the Combustion Performance of Different Vegetable Oils-Derived Biodiesel Fuels. Qing Shu, ChangLin Yu Chapter 10: Production of Gasoline, Naphtha, Kerosene, Diesel, and Fuel Oil Range Fuels from Polypropylene and Polystyrene Waste Plastics Mixture by Two-Stage Catalytic Degradation using ZnO. Moinuddin Sarker, Mohammad Mamunor Rashid

  19. State alternative route designations

    Energy Technology Data Exchange (ETDEWEB)

    1989-07-01

    Pursuant to the Hazardous Materials Transportation Act (HMTA), the Department of Transportation (DOT) has promulgated a comprehensive set of regulations regarding the highway transportation of high-level radioactive materials. These regulations, under HM-164 and HM-164A, establish interstate highways as the preferred routes for the transportation of radioactive materials within and through the states. The regulations also provide a methodology by which a state may select alternative routes. First,the state must establish a ``state routing agency,`` defined as an entity authorized to use the state legal process to impose routing requirements on carriers of radioactive material (49 CFR 171.8). Once identified, the state routing agency must select routes in accordance with Large Quantity Shipments of Radioactive Materials or an equivalent routing analysis. Adjoining states and localities should be consulted on the impact of proposed alternative routes as a prerequisite of final route selection. Lastly, the states must provide written notice of DOT of any alternative route designation before the routes are deemed effective.

  20. State alternative route designations

    Energy Technology Data Exchange (ETDEWEB)

    1989-07-01

    Pursuant to the Hazardous Materials Transportation Act (HMTA), the Department of Transportation (DOT) has promulgated a comprehensive set of regulations regarding the highway transportation of high-level radioactive materials. These regulations, under HM-164 and HM-164A, establish interstate highways as the preferred routes for the transportation of radioactive materials within and through the states. The regulations also provide a methodology by which a state may select alternative routes. First,the state must establish a state routing agency,'' defined as an entity authorized to use the state legal process to impose routing requirements on carriers of radioactive material (49 CFR 171.8). Once identified, the state routing agency must select routes in accordance with Large Quantity Shipments of Radioactive Materials or an equivalent routing analysis. Adjoining states and localities should be consulted on the impact of proposed alternative routes as a prerequisite of final route selection. Lastly, the states must provide written notice of DOT of any alternative route designation before the routes are deemed effective.

  1. Is garlic alternative medicine?

    Science.gov (United States)

    Rivlin, Richard S

    2006-03-01

    Garlic has been used medicinally since antiquity. In virtually every early civilization known, such as ancient India, Egypt, Rome, China, and Japan, garlic was part of the therapeutic regimen for a variety of maladies. Therefore, the ancient medicinal tradition of garlic use would qualify it as a folk medicine or as an alternative or complementary medicine. But is garlic an alternative to established methods of disease prevention or treatment? Scientists from around the world have identified a number of bioactive substances in garlic that are water soluble (e.g., S-allyl methylcysteine), and fat soluble (e.g., diallyldisulfide). Mechanisms of action are being elucidated by modern technology. The validity of ancient medicine is now being evaluated critically in cell-free systems, animal models, and human populations. Preventive and therapeutic trials of garlic are still in early stages. There are many promising lines of research suggesting the potential effects of garlic. The current state of knowledge does not recognize garlic as a true alternative, but it will likely find a place for garlic as a complement to established methods of disease prevention and treatment. Our goal should be to examine garlic together with other agents to evaluate its possible efficacy and toxicity under conditions of actual use in humans. PMID:16484549

  2. Alternative Energy Sources

    CERN Document Server

    Michaelides, Efstathios E (Stathis)

    2012-01-01

    Alternative Energy Sources is designed to give the reader, a clear view of the role each form of alternative energy may play in supplying the energy needs of the human society in the near and intermediate future (20-50 years).   The two first chapters on energy demand and supply and environmental effects, set the tone as to why the widespread use of alternative energy is essential for the future of human society. The third chapter exposes the reader to the laws of energy conversion processes, as well as the limitations of converting one energy form to another. The sections on exergy give a succinct, quantitative background on the capability/potential of each energy source to produce power on a global scale. The fourth, fifth and sixth chapters are expositions of fission and fusion nuclear energy. The following five chapters (seventh to eleventh) include detailed descriptions of the most common renewable energy sources – wind, solar, geothermal, biomass, hydroelectric – and some of the less common sources...

  3. Automation of procedure writing for the RLWTF

    International Nuclear Information System (INIS)

    In August of 1997, the Radioactive Liquid Waste Treatment Facility (RLWTF) at Los Alamos National Laboratory (LANL) recognized the need to re-engineer document management business process. All nuclear facilities at LANL are required to ensure that both the latest approved revision of controlled documents and any changes to those documents are available to operating personnel at all times. The Nuclear Materials Technology (NMT) Division was also re-engineering its document management business processes and searching for a solution. Both groups contacted several internal and external organizations in search of potential software solutions in use that would meet requirements. This report describes the objectives and features required by the software package, the choice of Procedure Design as the software package, and its implementation

  4. 76 FR 30189 - Receipt of Application for Approval

    Science.gov (United States)

    2011-05-24

    ... program for the Swift Parrot (Lathamus discolor). The approval would be for the cooperative breeding program and all its members, including the applicant. If approved, the program will be overseen by...

  5. 34 CFR 668.144 - Application for test approval.

    Science.gov (United States)

    2010-07-01

    ... distribution of test scores for each edition, form, level, sub-test, or partial battery, for which approval is... submitted to the Secretary for review and approval, documentation of periodic reviews of the content...

  6. Approved Drug Products with Therapuetic Equivalence Evaluations (Orange Book)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The publication Approved Drug Products with Therapeutic Equivalence Evaluations (the List, commonly known as the Orange Book) identifies drug products approved on...

  7. Doctors Often Overestimate Promise of Newly Approved Drugs

    Science.gov (United States)

    ... nlm.nih.gov/medlineplus/news/fullstory_158267.html Doctors Often Overestimate Promise of Newly Approved Drugs Many ... and Drug Administration's expedited approval process could mislead doctors about the new drugs' actual benefits, researchers warn. ...

  8. Advance crew procedures development techniques: Procedures generation program requirements document

    Science.gov (United States)

    Arbet, J. D.; Benbow, R. L.; Hawk, M. L.

    1974-01-01

    The Procedures Generation Program (PGP) is described as an automated crew procedures generation and performance monitoring system. Computer software requirements to be implemented in PGP for the Advanced Crew Procedures Development Techniques are outlined.

  9. Anesthesia for radiologic procedures

    International Nuclear Information System (INIS)

    Anesthetic techniques for neurodiagnostic studies and radiation therapy have been recently reviewed, but anesthetic involvement in thoracic and abdominal radiology has received little attention. Patient reactions to radiologic contrast media may be of concern to the anesthesiologist, who is often responsible for injecting these agents during diagnostic procedures, and thus is included in this discussion. Finally, the difficulties of administering anesthesia for magnetic resonance imaging (MRI) scans are outlined, in an effort to help anesthesiologist to anticipate problems with this new technologic development. Although there are very few indications for the use of general anesthesia for diagnostic radiologic studies in adults, most procedures performed with children, the mentally retarded, or the combative adult require either heavy sedation or general anesthesia. In selecting an anesthetic technique for a specific procedure, both the patient's disease process and the requirements of the radiologist must be carefully balanced

  10. Alternatives to animal testing: A review.

    Science.gov (United States)

    Doke, Sonali K; Dhawale, Shashikant C

    2015-07-01

    The number of animals used in research has increased with the advancement of research and development in medical technology. Every year, millions of experimental animals are used all over the world. The pain, distress and death experienced by the animals during scientific experiments have been a debating issue for a long time. Besides the major concern of ethics, there are few more disadvantages of animal experimentation like requirement of skilled manpower, time consuming protocols and high cost. Various alternatives to animal testing were proposed to overcome the drawbacks associated with animal experiments and avoid the unethical procedures. A strategy of 3 Rs (i.e. reduction, refinement and replacement) is being applied for laboratory use of animals. Different methods and alternative organisms are applied to implement this strategy. These methods provide an alternative means for the drug and chemical testing, up to some levels. A brief account of these alternatives and advantages associated is discussed in this review with examples. An integrated application of these approaches would give an insight into minimum use of animals in scientific experiments. PMID:26106269

  11. NRC perspective on alternative disposal methods

    International Nuclear Information System (INIS)

    In this paper is discussed an NRC staff strategy for the development of technical criteria and procedures for the licensing of various alternatives for disposal of low-level radioactive waste. Steps taken by the staff to identify viable alternative disposal methods and to comply with the requirements of the Low-Level Radioactive Waste Policy Amendments Act (LLRWPAA) of 1985 are also discussed. The strategy proposed by the NRC staff is to focus efforts in FY 87 on alternative concepts that incorporate concrete materials with soil or rock cover (e.g., below ground vaults and earth-mounded concrete bunkers), which several State and State Compacts have identified as preferred disposal options. While the NRC staff believes that other options, such as above ground vaults and mined cavities, are workable and licensable, the staff also believes, for reasons addressed in the paper, that it is in the best interest of the industry and the public to encourage standardization and to focus limited resources on a manageable number of alternative options. Therefore, guidance on above ground vaults, which are susceptible to long-term materials degradation due to climatological effects, and mined cavities, which represent a significant departure from the current experience base for low-level radioactive waste disposal, will receive minimal attention. 6 references

  12. 46 CFR 164.007-3 - Conditions of approval.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Conditions of approval. 164.007-3 Section 164.007-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Structural Insulations § 164.007-3 Conditions of approval. (a)...

  13. 50 CFR 15.26 - Approval of cooperative breeding programs.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Approval of cooperative breeding programs... WILDLIFE AND PLANTS WILD BIRD CONSERVATION ACT Permits and Approval of Cooperative Breeding Programs § 15.26 Approval of cooperative breeding programs. Upon receipt of a complete application, the...

  14. 8 CFR 207.6 - Control over approved refugee numbers.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Control over approved refugee numbers. 207... ADMISSION OF REFUGEES § 207.6 Control over approved refugee numbers. Current numerical accounting of approved refugees is maintained for each special group designated by the President. As refugee status...

  15. 46 CFR 160.036-4 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.036-4 Section 160.036... Distress Signals § 160.036-4 Approval and production tests. (a) Approval tests. The manufacturer must... Commandant under § 159.010 of this chapter. (b) Production inspections and tests. Production inspections...

  16. 46 CFR 160.040-5 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.040-5 Section 160.040... Rocket Type (and Equipment) § 160.040-5 Approval and production tests. (a) Approval tests. An independent... performance tests in paragraph (c) of this section. (b) Production inspections and tests....

  17. 46 CFR 160.037-4 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.037-4 Section 160.037... Approval and production tests. (a) Approval tests. The manufacturer must produce a lot of at least 100... chapter. (b) Production inspections and tests. Production inspections and tests of each lot of...

  18. 46 CFR 160.031-5 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.031-5 Section 160.031... Equipment) § 160.031-5 Approval and production tests. (a) Approval test. An independent laboratory accepted... operational test in paragraph (c) of this section. (b) Production inspections and tests....

  19. 46 CFR 160.022-4 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.022-4 Section 160.022... Minutes) § 160.022-4 Approval and production tests. (a) Approval tests. The manufacturer must produce a... Commandant under § 159.010 of this chapter. (b) Production inspections and tests. Production inspections...

  20. 46 CFR 160.024-4 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.024-4 Section 160.024... Signals § 160.024-4 Approval and production tests. (a) Approval tests. The manufacturer must produce a lot... under § 159.010 of this chapter. (b) Production inspections and tests. Production inspections and...

  1. 46 CFR 160.021-4 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.021-4 Section 160.021... Approval and production tests. (a) Approval tests. The manufacturer must produce a lot of at least 100... Chapter. (b) Production inspections and tests. Production inspections and tests of each lot of...

  2. 46 CFR 160.028-4 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.028-4 Section 160.028... § 160.028-4 Approval and production tests. (a) Approval test. An independent laboratory accepted by the... paragraph (c) of this section. (b) Production inspections and tests. Production inspections and tests...

  3. 46 CFR 160.057-4 - Approval and production tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Approval and production tests. 160.057-4 Section 160.057... Minutes) § 160.057-4 Approval and production tests. (a) Approval tests. The manufacturer must produce a... under § 159.010 of this chapter. (b) Production inspections and tests. Production inspections and...

  4. 7 CFR 996.22 - USDA-approved laboratory.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false USDA-approved laboratory. 996.22 Section 996.22 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... laboratory. USDA-approved laboratory means laboratories approved by the Science and Technology...

  5. 14 CFR 21.269 - Export airworthiness approvals.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Export airworthiness approvals. 21.269 Section 21.269 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION....269 Export airworthiness approvals. The manufacturer may issue export airworthiness approvals....

  6. 18 CFR 12.34 - Approval of independent consultant.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Approval of independent... PROJECT WORKS Inspection by Independent Consultant § 12.34 Approval of independent consultant. At least 60... Director of the Office of Energy Projects Licensing for approval, with a copy to the Regional Engineer,...

  7. 46 CFR 8.530 - Plan development and approval.

    Science.gov (United States)

    2010-10-01

    ... develop the CAP and VAP with guidance from the Coast Guard SIP Advisor for OCMI approval. (a) Company Action Plan. The CAP shall include at least the following: (1) A copy of the OCMI CAP approval letter (once the CAP is approved). (2) An organization commitment statement. (3) A company organization...

  8. 48 CFR 2806.304 - Approval of the justification.

    Science.gov (United States)

    2010-10-01

    ... justification. 2806.304 Section 2806.304 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE... Approval of the justification. (a) All justifications for contract actions over the contracting officer's... contracting activity competition advocate for approval. Justifications requiring approval by the PE shall...

  9. 48 CFR 570.502-1 - Justification and approval requirements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Justification and approval... Contracting for Lease Alterations 570.502-1 Justification and approval requirements. If the proposed... competition, the following justification and approval requirements apply: (a) If the alteration project...

  10. 48 CFR 606.304 - Approval of the justification.

    Science.gov (United States)

    2010-10-01

    ... justification. 606.304 Section 606.304 Federal Acquisition Regulations System DEPARTMENT OF STATE COMPETITION... Approval of the justification. (a)(2) The approval authority for a proposed contract over $550,000 but not... determining the approval level of a justification....

  11. 48 CFR 1306.304 - Approval of the justification.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Approval of the justification. 1306.304 Section 1306.304 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE... Approval of the justification. The designee authorized to approve justifications for other than full...

  12. 38 CFR 17.804 - Loan approval criteria.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Loan approval criteria... Transitional Housing Loan Program § 17.804 Loan approval criteria. Upon consideration of the application package, loan approval will be based on the following: (a) Favorable financial history and status, (1)...

  13. 46 CFR 131.710 - Approved work vests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Approved work vests. 131.710 Section 131.710 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Work Vests § 131.710 Approved work vests. Each buoyant work vest carried aboard must be approved under subpart...

  14. 7 CFR 1717.609 - RUS approval of general manager.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false RUS approval of general manager. 1717.609 Section... Operational Controls § 1717.609 RUS approval of general manager. (a) If a borrower's mortgage or loan contract grants RUS the unconditioned right to approve the employment and/or the employment contract of...

  15. 7 CFR 1717.308 - RUS approval of nonconforming rates.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false RUS approval of nonconforming rates. 1717.308 Section... Federal Pre-emption in Rate Making in Connection With Power Supply Borrowers § 1717.308 RUS approval of nonconforming rates. Borrowers may request and RUS may approve rates which do not conform with the...

  16. 46 CFR 162.050-23 - Separator: Approval tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Separator: Approval tests. 162.050-23 Section 162.050-23...: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Pollution Prevention Equipment § 162.050-23 Separator: Approval... and influent pressure equal to the maximum throughput and pressure at which the separator being...

  17. [Requirements for drug approval and additional benefits assessment: Regulatory aspects and experiences].

    Science.gov (United States)

    Broich, K; Löbker, W; Schulte, A; Beinlich, P; Müller, T

    2016-04-01

    The early assessment of benefits of newly approved drugs with novel active substances or new applications, which came into force on 1 January 2011 still represents a challenge to all parties involved. This article highlights the definitions, regulatory requirements and interaction between drug marketing approval and early assessment of benefits in Germany. The constellation of an extensively harmonized European and even international drug authorization process with a predominantly national regulation of drug reimbursement situation inevitably causes friction, which could be markedly reduced through early joint advisory discussions during the planning phase for pivotal clinical trials. During the year 2015 the Federal Institute for Drugs and Medical Devices (BfArM) carried out 300 scientific advice procedures of which 34 were concerned with applications in the field of indications for the central nervous system (CNS). In comparison 98 advisory meetings were held by the Federal Joint Committee (G-BA) of which the BfArM provided advice in 12 instances and in 2 cases on CNS indications. Study design, endpoints and appropriate comparative therapies are the key issues in exchanges and discussions between the BfArM, the G‑BA and applicants. Under these aspects the BfArM and G‑BA promote an early and consistent involvement in early advice procedures regarding the prerequisites for drug approval and assessment of additional benefits. PMID:27003322

  18. Decision-making Procedures

    DEFF Research Database (Denmark)

    Aldashev, Gani; Kirchsteiger, Georg; Sebald, Alexander Christopher

    2009-01-01

    define procedures as mechanisms that influence the probabilities of reaching different endnodes. We show that for such procedural games a sequential psychological equilibrium always exists. Applying this approach within a principal-agent context we show that the way less attractive jobs are allocated is...... crucial for the effort exerted by agents. This prediction is tested in a field experiment, where some subjects had to type in data, whereas others had to verify the data inserted by the typists. The controllers' wage was 50% higher than that of the typists. In one treatment the less attractive typists...

  19. The separation procedure.

    Science.gov (United States)

    Kiely, Edward M; Spitz, Lewis

    2015-10-01

    The various stages of the separation are carefully planned but despite this, variations which will change the schedule of the procedure may exist. In general the operation commences on the opposite side from the main procedure and then the twins are turned for the remainder of the operation. Each type of conjoined twin is different but basically thoracopagus involves the hearts, omphalopagus involves the liver and small intestine and ischiopagus involves the large intestine and genito-urinary system. Our results are presented together with interesting cases from which lessons have been learned. PMID:26382263

  20. "Les Grangettes" no longer approved hospital as of 1.1.2012

    CERN Multimedia

    HR Department

    2012-01-01

    The negotiations for a new tariff agreement with "Les Grangettes", conducted jointly by CERN and partner international organizations, did not reach a positive conclusion. As a result, "Les Grangettes" ceased being an approved hospital on 31 December 2011.   This means that for hospitalizations in "Les Grangettes" as of 1 January 2012 the conditions applicable to unapproved hospitals will apply. In particular: no third-party payment (i.e. you will be charged directly); reimbursement at a fixed 80% rate, whatever the expenses incurred; and expenses incurred will not contribute towards increasing FCA. CHIS members looking for an alternative are invited to consider “Clinique Générale Beaulieu” (located in the same area of Geneva and with which the existing agreement has been extended for 2012 and 2013) or another approved hospital (see the list on the CHIS web site). Note that, as a transitory measur...