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Sample records for aloe arborescens miller

  1. The complete amino acid sequence of a mannose-binding lectin from "Kidachi Aloe" (Aloe arborescens Miller var. natalensis Berger).

    Science.gov (United States)

    Koike, T; Titani, K; Suzuki, M; Beppu, H; Kuzuya, H; Maruta, K; Shimpo, K; Fujita, K

    1995-09-01

    The complete amino acid sequence of a mannose-binding lectin purified from the leaf skin of "Kidachi Aloe" (Aloe arborescens Miller var. natalensis Berger) is presented. The 109-residue sequence of the subunit was determined by analysis of peptides of the intact or S-pyridylethylated protein generated by digestion with cyanogen bromide, BNPS-skatole, Achromobacter protease I, or trypsin. The subunit contains an intrachain disulfide bridge. The sequence is highly homologous to that of a mannose-binding lectin from snowdrop bulb. PMID:7669035

  2. Efeito da Aloe arborescens Miller e da Aloe barbadensis Miller sobre o desenvolvimento vegetativo em Aspergillus nidulans

    Directory of Open Access Journals (Sweden)

    A. P. BERTI

    2015-12-01

    Full Text Available RESUMOA pesquisa de produtos naturais benéficos à saúde humana vem crescendo nos últimos 20 anos. Considerando que as plantas de Aloe são amplamente utilizadas pela população humana, em geral de maneira terapêutica, o objetivo deste estudo foi avaliar os efeitos de Aloearborescens Miller e Aloe barbadensis Miller, sobre o desenvolvimento vegetativo de linhagens normais e mutantes de Aspergillus nidulans. Conídios da linhagem biA1methG1, MSE e CLB3 de A. nidulans, foram inoculados em meio completo sem (Controle e com extratos das duas espécies incubados por 2, 4, 6 e 8 horas a 37ºC, no escuro. Foi analisado em microscópio óptico, 200 conídios de cada tratamento. Para o desenvolvimento das colônias, as linhagens foram inoculadas no centro das placas juntamente com o meio de cultura sólido e sobre a membrana de diálise, visando a medição do diâmetro e do peso. A análise estatística foi baseada no teste de Tukey e todos os procedimentos experimentais foram conduzidos em triplicata. Todas as linhagens apresentaram interferências positivas quando expostas às plantas de Aloe, porém, de maneira variada. Ambas as espécies aceleraram a germinação em todas as linhagens testadas e atuaram na redução significativa de conídios mortos e/ou malformados. Em relação ao desenvolvimento vegetativo, todos os dados referentes ao peso úmido e diâmetro corrigido dos tratamentos demonstraram progressos, contudo, a razão diâmetro/peso apresentou somente na linhagem MSE, ação favorável dos tratamentos naturais. As informações deste estudo sugerem benefícios de A. arborescens e A. barbadensis, justificando a importância e continuidade da investigação, para melhor elucidar os mecanismos de ação dessas plantas.

  3. Radical-scavenging effects of Aloe arborescens Miller on prevention of pancreatic islet B-cell destruction in rats.

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    Beppu, Hidehiko; Koike, Takaaki; Shimpo, Kan; Chihara, Takeshi; Hoshino, Motoyuki; Ida, Chikako; Kuzuya, Hiroshi

    2003-11-01

    We evaluated the possible scavenging effects of Aloe arborescens Miller var. natalensis Berger (Kidachi aloe in Japanese) on free radicals generated by streptozotocin (Sz) or alloxan (Ax). The components of Kidachi aloe were added to a reaction system in which .OH radicals derived from Sz or Ax as pancreatic islet B-cell toxins and hypoxanthine-xanthine oxidase (HX-XO)-derived O(2) radicals destroy isolated islet B-cells, and we observed its preventive effects. The Kidachi aloe components inhibited the destruction of rat pancreatic islet B-cells by Sz, Ax or HX-XO. These components were prepared in the form of a freeze-dried powder of the boiled leaf skin of Kidachi aloe, and measurement of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity showed higher radical-scavenging activity in this boiled leaf skin powder than the non-boiled leaf skin powder.Furthermore, HPLC chromatograms of the "Boiled leaf skin powder" were similar to those of commercially available aloin (barbaloin content: approximately 20%). Therefore, the main component may be a phenol compound. In addition, the phenolic fraction of the Boiled leaf skin contained large amounts of 2'-O-p-coumaroylaloesin and 2'-O-feruloylaloesin, which have higher DPPH radical-scavenging activity than barbaloin. These results suggest that the action mechanism of Kidachi aloe Boiled leaf skin components, which prevent destruction of the pancreatic islets by specific pancreatic islet toxins such as Sz, Ax, and HX-XO, involves inhibition of free radical-scavenging effects, and may be associated with a thermostable low molecular component. The co-existence of Kidachi aloe-derived 2'-O-p-coumaroylaloesin, 2'-O-feruloylaloesin, and aloin may result in the potentiation of radical-scavenging activity. PMID:14522430

  4. One-year chronic toxicity study of Aloe arborescens Miller var. natalensis Berger in Wistar Hannover rats. A pilot study.

    Science.gov (United States)

    Matsuda, Yoko; Yokohira, Masanao; Suzuki, Satoshi; Hosokawa, Kyoko; Yamakawa, Keiko; Zeng, Yu; Ninomiya, Fumiko; Saoo, Kousuke; Kuno, Toshiya; Imaida, Katsumi

    2008-02-01

    This study was conducted to evaluate the chronic toxicity of Aloe arborescens Miller var. natalensis Berger (ALOE) in the diet at doses of 4.0%, 0.8% or 0.16% to groups of male and female Wistar Hannover rats. No deaths occurred at any dose level throughout the treatment period. Both sexes receiving 4.0% showed diarrhea, with a reduced body weight gain. Increase of WBCs in the male 4.0% group, decrease of Hb in the female 4.0% and 0.8% groups, decrease of IP in the male 4.0% and 0.8% groups and female 4.0% group, and decrease of Ca and ALT in the female 4.0% group were observed. Relative kidney weight showed increase in the female 4.0% group and relative heart and brain weights were decreased in the female 4.0% and 0.8% groups. Histopathologically, both sexes receiving 4.0% showed severe sinus dilatation of ileocecal lymph nodes, and yellowish pigmentation of ileocecal lymph nodes and renal tubules. In conclusion, the no observed adverse effect level (NOAEL) for ALOE was the 0.16% in diet, which is equivalent to 87.7 and 109.7 mg/kg/day in males and females, respectively. PMID:17981383

  5. Potencial fitotóxico de extratos foliares de Aloe arborescens Miller (Asphodelaceae produzidos em diferentes épocas do ano Analysis of the phytotoxic potential of Aloe arborescens Miller leaf extracts (Asphodelaceae produced at different times of the year

    Directory of Open Access Journals (Sweden)

    Cynthia Murakami

    2009-03-01

    Full Text Available Este trabalho visou analisar o potencial fitotóxico de extratos foliares de Aloe arborescens Miller sobre a germinação e crescimento de plântulas de alface (Lactuca sativa L.. Amostras de folhas foram coletadas nas quatro estações climáticas e maceradas em etanol P.A. por 28 dias. Os extratos produzidos foram fracionados em extratos etanólico e clorofórmico e tiveram as concentrações reduzidas a 1%. Os bioensaios de ação fitotóxica foram desenvolvidos em triplicata, sob luz constante e temperatura ambiente. Apenas o extrato clorofórmico de primavera mostrou forte atividade fitotóxica sobre a germinação das sementes de alface (16,67%. Todos os extratos reduziram significativamente a primeira contagem, índice de velocidade germinação (IVG e o crescimento do eixo hipocótiloradicular (EHR das plântulas de alface, porém os extratos clorofórmicos mostraram maior atividade fitotóxica, gerando alterações morfológicas mais intensas sobre as plântulas de alface e apresentaram maiores teores de compostos fenólicos. Apesar de todos os extratos clorofórmicos inibirem fortemente o crescimento das folhas cotiledonares das plântulas de alface, não se observaram neste último efeito, variações em função dos períodos de coleta.This study aimed to analyze seasonal variation in the phytotoxic potential of Aloe arborescens Miller leaf extract on lettuce (Lactuca sativa L. germination and growth. Leaf samples were collected in the four seasons and were macerated in ethanol P.A. for 28 days. The extracts were fractionated into solutions made with ethanol and chloroform, and concentrations were reduced to 1%. Phytotoxic activity bioassays were carried out in triplicate, under constant light and ambient temperature. Only the spring chloroform extract showed strong phytotoxic activity on lettuce seed germination (16.67%. All extracts significantly reduced the first count, germination velocity index (GVI and growth of the hipocotyl

  6. A 35 kDa mannose-binding lectin with hemagglutinating and mitogenic activities from "Kidachi Aloe" (Aloe arborescens Miller var. natalensis Berger).

    Science.gov (United States)

    Koike, T; Beppu, H; Kuzuya, H; Maruta, K; Shimpo, K; Suzuki, M; Titani, K; Fujita, K

    1995-12-01

    A novel lectin was isolated from the leaf skin of "Kidachi Aloe" (Aloe arborescens Miller var. natalensis Berger) by sequential chromatographies on Sephadex G-25 gel filtration, DEAE ion exchange, and Superdex 75 gel filtration columns. The native lectin exhibited a molecular mass of about 35 kDa on both gel filtration on a Superdex 75 column and native-PAGE under nonreducing conditions. SDS-PAGE in the presence or absence of beta-mercaptoethanol revealed two distinct peptides with molecular masses of about 5.5 and 2.3 kDa, respectively, in addition to a major 9.2 kDa subunit, indicating the presence of a partially processed subunit. The N-terminal amino acid sequence of the intact subunit showed homology with that of snowdrop lectin. The native lectin showed hemagglutinating activity toward rabbit but not human and sheep erythrocytes, and specifically bound to mannose like snowdrop lectin did, indicating that the Aloe and snowdrop lectins are structurally and functionally similar proteins. In addition, the native lectin showed strong mitogenic activity toward mouse lymphocytes. PMID:8720136

  7. Inhibition of N-ethyl-N'-nitro-N-nitrosoguanidine-induced Duodenal Tumorigenesis in Mice by Whole-leaf Aloe arborescens Miller var. natalensis Berger.

    Science.gov (United States)

    Shimpo, Kan; Chikako, Takeshi; Shinzato, Masanori; Beppu, Hidehiko; Kaneko, Takaaki; Ida, Chikako; Kawai, Kaoru; Hirono, Iwao; Shamoto, Mikihiro; Nagatsu, Toshiharu; Kuzuya, Hiroshi

    2000-01-01

    We examined the modifying effects of freeze-dried whole-leaf Aloe arborescens Miller var. natalensis Berger (designated as 'ALOE') on N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG)-induced duodenal tumorigenesis in C57BL/6 mice. Experiment 1: Male mice were given ENNG in drinking water for the first 4 weeks, and then 10% ALOE in basal diet for 16 weeks. Experiment 2: Female mice were given ENNG for 5 weeks, and then 5%, 1% or 0.2% ALOE in the diet were given for 15 weeks. In Experiment 1, the tumor incidence and tumor multiplicity (tumors per mouse) of the duodenum in the ENNG + 10% ALOE group were significantly decreased compared with that in the ENNG alone group. Erythrocyte polyamine levels in the ENNG + 10% ALOE group were also significantly decreased. In Experiment 2, the incidence of duodenal tumors in the ENNG + 5% ALOE group were significantly decreased compared with that in the ENNG alone group. These results indicated that ALOE, especially at 10% in the diet, inhibits ENNG-induced duodenal tumorigenesis in mice. PMID:12716301

  8. Inhibition of azoxymethane-induced aberrant crypt foci formation in rat colorectum by whole leaf Aloe arborescens Miller var. natalensis Berger.

    Science.gov (United States)

    Shimpo, K; Chihara, T; Beppu, H; Ida, C; Kaneko, T; Nagatsu, T; Kuzuya, H

    2001-12-01

    We examined the modifying effect of whole-leaf Aloe arborescens Miller var. natalensis Berger (designated as 'ALOE') on azoxymethane (AOM)-induced aberrant crypt foci (ACF), putative preneoplastic lesions, in the rat colorectum. Male F344 rats (4 weeks old) were fed the basal diet, or experimental diets containing 1% or 5% ALOE for 5 weeks. One week later, all rats except those in the vehicle-treated groups were injected s.c. with AOM (15 mg/kg, once weekly for 3 weeks). At 9 weeks of age, all the rats were killed, and the colorectum and liver were evaluated for ACF and cytosolic quinone reductase (QR; a phase 2 enzyme), respectively. In rats given AOM and ALOE (1% or 5% in diet) the numbers of ACF/colorectum, aberrant crypts/colorectum, aberrant crypts/focus and large ACF/colorectum were significantly decreased compared with those of rats given AOM alone (all p ALOE significantly increased cytosolic QR activity in the liver (p ALOE inhibited the development of AOM-induced ACF in the rat colorectum, with increased QR activity in the liver, and therefore suggested that ALOE might have a chemopreventive effect against colon carcinogenesis at least in the initiation stage. PMID:11746864

  9. Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components.

    Science.gov (United States)

    Beppu, Hidehiko; Shimpo, Kan; Chihara, Takeshi; Kaneko, Takaaki; Tamai, Ikuko; Yamaji, Sachiyo; Ozaki, Sayaka; Kuzuya, Hiroshi; Sonoda, Shigeru

    2006-02-20

    We carried out three experimental trials to determine antidiabetic effects of Aloe arborescens Miller components. Firstly, ICR mice which received frequent injections of streptozotocin (Sz) in small doses (low-dose Sz-induced diabetes mice) were fed ad libitum with basal diets supplemented with components of Aloe arborescens Miller var. natalensis Berger (Kidachi aloe) and Aloe vera Linne from 31 days before to 73 days after the Sz injections. Variation in blood glucose levels, incidence rates of insulitis and blood insulin levels were examined during the trial. As a result, groups receiving diets supplemented at the rate of 2% with whole leaf of Kidachi aloe and 10 KDa fraction powder (a fraction with less than 10 KDa molecular weight derived from Kidachi aloe leaf skin juice by ultra filtration) significantly suppressed the elevation of blood sugar as compared to a control group receiving basal diet. In contrast, there was no significant effect with Aloe vera leaf pulp powder. Insulitis emerged at the rate of 87% in the basal diet group. On the contrary, the whole aloe leaf and 10 KDa fraction groups significantly decreased the incidence of insulitis and incidence rates of whole aloe leaf and 10 KDa fraction powder were 51 and 38%, respectively. While insulin levels in the basal diet group averaged at 0.05 ng, more than four times the insulin level was observed in the 10 KDa group relative to the basal diet group. Secondary, the inhibitory effects of test materials on intestinal glucose absorption were observed using the jejunum of rats. A strong inhibitory action on intestinal glucose absorption was observed in the 10 KDa fraction powder group. Thirdly, phenol compounds derived from aloe in the blood serum and organs were quantitatively measured by a HPLC following forced administration of aloe components to rats to determine absorption kinetics of aloe components inside the body. The primary component of aloe phenol compounds is the same component of the 10 KDa

  10. Equivocal colonic carcinogenicity of Aloe arborescens Miller var. natalensis berger at high-dose level in a Wistar Hannover rat 2-y study.

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    Yokohira, M; Matsuda, Y; Suzuki, S; Hosokawa, K; Yamakawa, K; Hashimoto, N; Saoo, K; Nabae, K; Doi, Y; Kuno, T; Imaida, K

    2009-03-01

    A 2-y carcinogenicity study of Aloe, Aloe arborescens Miller var. natalensis Berger, a food additive, was conducted for assessment of toxicity and carcinogenic potential in the diet at doses of 4% or 0.8% in groups of male and female Wistar Hannover rats. Both sexes receiving 4% showed diarrhea, with loss of body weight gain. The survival rate in the 4% female group was significantly increased compared with control females after 2 y. Hematological and biochemical examination showed increase of RBC, Hb, and Alb in the 4% males. The cause of these increases could conceivably have been dehydration through diarrhea. AST and Na were significantly decreased in the males receiving 4%, and Cl was significantly decreased in both 4% and 0.8% males. A/G was significantly increased in the 4% females, and Cl was significantly decreased (0.8%) in the female group. Histopathologically, both sexes receiving 4% showed severe sinus dilatation of ileocecal lymph nodes, and yellowish pigmentation of ileocecal lymph nodes and renal tubules. Adenomas or adenocarcinomas in the cecum, colon, and rectum were observed in 4% males but not in the 0.8% and control male groups. Similarly, in females, adenomas in the colon were also observed in the 4% but not 0.8% and control groups. In conclusion, Aloe, used as a food additive, exerted equivocal carcinogenic potential at 4% high-dose level on colon in the 2-y carcinogenicity study in rats. Aloe is not carcinogenic at nontoxic-dose levels and that carcinogenic potential in at 4% high-dose level on colon is probably due to irritation of the intestinal tract by diarrhea. PMID:19323775

  11. Biopolímers del Aloe Barbadensis i Aloe Arborescens

    OpenAIRE

    Navarro Barbero, Rosa Mª

    2009-01-01

    El Aloe Vera (Aloe Barbadensis Miller) es una planta perenne de la familia liliacea, que puede crecer en todo el mundo, incluso las zonas desérticas. La composición química de las plantas de Aloe depende en gran medida de las especies analizadas. Una característica destacada del filete de Aloe vera es su alto contenido en agua, en un rango de 98,5 a 99,5% de materia fresca. Más del 60% de los sólidos restantes están formados por polisacáridos, lo que constituirá una parte de es...

  12. A biochemical and cellular approach to explore the antiproliferative and prodifferentiative activity of Aloe arborescens leaf extract.

    Science.gov (United States)

    Di Luccia, Blanda; Manzo, Nicola; Vivo, Maria; Galano, Eugenio; Amoresano, Angela; Crescenzi, Elvira; Pollice, Alessandra; Tudisco, Raffaella; Infascelli, Federico; Calabrò, Viola

    2013-12-01

    Aloe arborescens Miller, belonging to the Aloe genus (Liliaceae family), is one of the main varieties of Aloe used worldwide. Although less characterized than the commonest Aloe vera, Aloe arborescens is known to be richer in beneficial phytotherapeutic, anticancer, and radio-protective properties. It is commonly used as a pharmaceutical ingredient for its effect in burn treatment and ability to increase skin wound healing properties. However, very few studies have addressed the biological effects of Aloe at molecular level. The aim of the research is to provide evidences for the antiproliferative properties of Aloe arborescens crude leaf extract using an integrated proteomic and cellular biological approach. We analysed the composition of an Aloe arborescens leaf extract by gas chromatography-mass spectrometry analysis. We found it rich in Aloe-emodin, a hydroxylanthraquinone with known antitumoral activity and in several compounds with anti-oxidant properties. Accordingly, we show that the Aloe extract has antiproliferative effects on several human transformed cell lines and exhibits prodifferentiative effects on both primary and immortalized human keratinocyte. Proteomic analysis of whole cell extracts revealed the presence of proteins with a strong antiproliferative and antimicrobial activity specifically induced in human keratinocytes by Aloe treatment supporting its application as a therapeutical agent. PMID:23418125

  13. 开普芦荟和木立芦荟的染色体核型分析%KARYOTYPE ANALYSIS OF ALOE FEROX MILLER AND ALOE ARBORESCENS MILLER

    Institute of Scientific and Technical Information of China (English)

    梁秀梅; 卜秀玲

    2001-01-01

    对盆栽开普卢荟(Aloe ferox Miller)和木立卢荟(Aloe a rborescens Miller) 植物根尖细胞的染色体进行了观察分析。结果表明开普芦荟和木立芦荟的染色体数与已见报导的百合科(Liliaceae)中国芦荟(Alov vera var.chinensis)植物染色体数相同,2n=14。染色体类型按Levan方法分类,没有近端部染色体和随体。开普芦荟和木立芦荟的染色体核型分析结果均为 K(2n)=2x=4sm+10st。根据Stebbins的核型分类标准,开普芦荟的核型为“4C”型,而木立芦荟的核型为“3C”型。两种芦荟染色体相对长度组成均为2n=14=6L+2M 2+6S 。根据核型研究,可以确定百合科开普芦荟和木立芦荟的染色体基数为X=7。

  14. Immune modulatory effects of Aloe arborescens extract on the piscine SAF-1 cell line.

    Science.gov (United States)

    Picchietti, S; Bernini, C; Belardinelli, M C; Ovidi, E; Taddei, A R; Guerra, L; Abelli, L; Fausto, A M

    2013-05-01

    The pharmacological potential of Aloe arborescens Miller leaf components was investigated, with special attention deserved to immune modulatory effects on the Sparus aurata fibroblast cell line SAF-1. The cells were treated with Aloe extract at different concentrations (1.2-4.8 mg ml(-1)) for various times (24-72 h). The lowest concentration did not provoke any cellular damage observable by SEM and did not affect ATP amounts after 24 and 48 h, while even induced a significant increase over controls after 72 h. We next examined the transcription kinetics of different immune-related genes (IL-1β, TGF-β, TNF-α, COX-2, IFN-I, Mx and MHCI-α) in SAF-1 cells stimulated with LPS or poly I:C. The Aloe extract (1.2 mg ml(-1)) acted as a powerful immune stimulant in LPS- or poly I:C-activated SAF-1 cells, inducing a synergic effect on interconnected genes that are expected to be involved in different aspects of the immune responses. These reports provide a new perspective for the use of A. arborescens to prevent or oppose bacterial and viral fish diseases and to face, as an alternative strategy based on natural plant extracts, the growing unwillingness to rely upon standard solutions involving antibiotics or antimicrobial chemicals. PMID:23470814

  15. TECHNOLOGICAL ASPECTS CONCERNING PRODUCTION ON ASEXUAL TRACK OF ORNAMENTAL CULTURE OF ALOE ARBORESCENS

    OpenAIRE

    Mădălina Doltu; Marian Bogoescu; Dorin Sora; Marian Vintilă

    2012-01-01

    Research conducted in culture of Aloe arborescens Mill., in conditions of protected area (greenhouse), had to watch some of technological aspects to obtain some in pot ornamentals plants, competitive plants for european market. Experience has included plants of Aloe arborescens Mill., aged 1-5 years, obtained by vegetative multiplying, asexual. Production technology was applied to aloe plants (multiplying, transplanting, maintenance), taking into account the ecological requirements of specie ...

  16. Caracterización morfoanatómica comparativa entre Aloe vera (L. Burm. F., Aloe arborescens Mill., Aloe saponaria Haw. y Aloe ciliaris Haw. (Aloeaceae

    Directory of Open Access Journals (Sweden)

    Stella Maris Carpano

    2009-03-01

    Full Text Available Aloe vera (L. Burm. F. (= Aloe barbadensis Miller conhecida como "a planta da imortalidade" no antigo Egito é utilizada em fitoterapia como humectante, antibacteriana, antifúngica, antiviral e antioxidante. Com a finalidade de contribuir para identificação da droga vegetal, foram realizados estudos morfoanatômicos da folha. A utilização de plantas com características terapêuticas reconhecidas determina que, por analogia, popularmente sejam utilizadas com a mesma finalidade outras espécies do mesmo gênero. Isto é o que ocorre com três espécies de Aloe spp., que se cultivam ou crescem acidentalmente na Argentina: A. arborescens Mill., A. saponaria Haw. e A. ciliaris Haw. (Aloaceae. Estabeleceram-se os caracteres morfoanatômicos de diagnóstico por microscopia óptica e microscopia eletrônica de varredura (apresentam-se desenhos e fotomicrografias dos mesmos. Obtiveram-se valores numéricos dos elementos histológicos de diagnóstico: magnitudes lineares e proporcionais. Realizaram-se reações histoquímicas de identificação dos princípios ativos para sua localização "in situ".

  17. [Tissue culture and rapid propagation of Aloe arborescens].

    Science.gov (United States)

    Zeng, S; Peng, X

    2000-02-01

    Tissue culture and rapid propagation of Aloe arborescens have been studied. The main results are as follows: the optimum medium for cluster shoots induction is MS + 6-BA 3.0 mg/L + NAA 0.2 mg/L; for cluster shoots propagation is MS + 6-BA 2.0 mg/L + NAA 0.2 mg/L; for roots induction is 1/2 MS + NAA 0.5 mg/L. The survival rate of the tube plantlets is 100% in the transplanting. Cutting down the cost of medium in large scale of production have been studied also. PMID:12575139

  18. A Systemic Review on Aloe arborescens Pharmacological Profile: Biological Activities and Pilot Clinical Trials.

    Science.gov (United States)

    Singab, Abdel-Naser B; El-Hefnawy, Hala M; Esmat, Ahmed; Gad, Haidy A; Nazeam, Jilan A

    2015-12-01

    Since ancient times, plants and herbal preparations have been used as medicine. Research carried out in the last few decades has verified several such claims. Aloe arborescens Miller, belonging to the Aloe genus (Family Asphodelaceae), is one of the main varieties of Aloe used worldwide. The popularity of the plant in traditional medicine for several ailments (antitumor, immunomodulatory, antiinflammatory, antiulcer, antimicrobial and antifungal activity) focused the investigator's interest on this plant. Most importantly, the reported studies have shown the plant effectiveness on various cancer types such as liver, colon, duodenal, skin, pancreatic, intestinal, lung and kidney types. These multiple biological actions make Aloe an important resource for developing new natural therapies. However, the biological activities of isolated compounds such as glycoprotein, polysaccharides, enzyme and phenolics were insufficient. Considering all these, this contribution provides a systematic review outlining the evidence on the biological efficacy of the plant including the pharmacology and the related mechanisms of action, with specific attention to the various safety precautions, and preclinical and clinical studies, indicating the future research prospects of this plant. PMID:26768148

  19. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice,aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract.

    Science.gov (United States)

    2007-01-01

    Plant materials derived from the Aloe plant are used as cosmetic ingredients, including Aloe Andongensis Extract, Aloe Andongensis Leaf Juice, Aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice, Aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract. These ingredients function primarily as skin-conditioning agents and are included in cosmetics only at low concentrations. The Aloe leaf consists of the pericyclic cells, found just below the plant's skin, and the inner central area of the leaf, i.e., the gel, which is used for cosmetic products. The pericyclic cells produce a bitter, yellow latex containing a number of anthraquinones, phototoxic compounds that are also gastrointestinal irritants responsible for cathartic effects. The gel contains polysaccharides, which can be acetylated, partially acetylated, or not acetylated. An industry established limit for anthraquinones in aloe-derived material for nonmedicinal use is 50 ppm or lower. Aloe-derived ingredients are used in a wide variety of cosmetic product types at concentrations of raw material that are 0.1% or less, although can be as high as 20%. The concentration of Aloe in the raw material also may vary from 100% to a low of 0.0005%. Oral administration of various anthraquinone components results in a rise in their blood concentrations, wide systemic distribution, accumulation in the liver and kidneys, and excretion in urine and feces; polysaccharide components are distributed systemically and metabolized into smaller molecules. aloe-derived material has fungicidal, antimicrobial, and antiviral activities, and has been effective in wound healing and infection treatment in animals. Aloe barbadensis (also known as Aloe vera)-derived ingredients were not toxic

  20. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice,aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract.

    Science.gov (United States)

    2007-01-01

    Plant materials derived from the Aloe plant are used as cosmetic ingredients, including Aloe Andongensis Extract, Aloe Andongensis Leaf Juice, Aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice, Aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract. These ingredients function primarily as skin-conditioning agents and are included in cosmetics only at low concentrations. The Aloe leaf consists of the pericyclic cells, found just below the plant's skin, and the inner central area of the leaf, i.e., the gel, which is used for cosmetic products. The pericyclic cells produce a bitter, yellow latex containing a number of anthraquinones, phototoxic compounds that are also gastrointestinal irritants responsible for cathartic effects. The gel contains polysaccharides, which can be acetylated, partially acetylated, or not acetylated. An industry established limit for anthraquinones in aloe-derived material for nonmedicinal use is 50 ppm or lower. Aloe-derived ingredients are used in a wide variety of cosmetic product types at concentrations of raw material that are 0.1% or less, although can be as high as 20%. The concentration of Aloe in the raw material also may vary from 100% to a low of 0.0005%. Oral administration of various anthraquinone components results in a rise in their blood concentrations, wide systemic distribution, accumulation in the liver and kidneys, and excretion in urine and feces; polysaccharide components are distributed systemically and metabolized into smaller molecules. aloe-derived material has fungicidal, antimicrobial, and antiviral activities, and has been effective in wound healing and infection treatment in animals. Aloe barbadensis (also known as Aloe vera)-derived ingredients were not toxic

  1. Novel type III polyketide synthases from Aloe arborescens.

    Science.gov (United States)

    Mizuuchi, Yuusuke; Shi, She-Po; Wanibuchi, Kiyofumi; Kojima, Akiko; Morita, Hiroyuki; Noguchi, Hiroshi; Abe, Ikuro

    2009-04-01

    Aloe arborescens is a medicinal plant rich in aromatic polyketides, such as pharmaceutically important aloenin (hexaketide), aloesin (heptaketide) and barbaloin (octaketide). Three novel type III polyketide synthases (PKS3, PKS4 and PKS5) were cloned and sequenced from the aloe plant by cDNA library screening. The enzymes share 85-96% amino acid sequence identity with the previously reported pentaketide chromone synthase and octaketide synthase. Recombinant PKS4 and PKS5 expressed in Escherichia coli were functionally identical to octaketide synthase, catalyzing the sequential condensations of eight molecules of malonyl-CoA to produce octaketides SEK4/SEK4b. As in the case of octaketide synthase, the enzymes are possibly involved in the biosynthesis of the octaketide barbaloin. On the other hand, PKS3 is a multifunctional enzyme that produces a heptaketide aloesone (i.e. the aglycone of aloesin) as a major product from seven molecules of malonyl-CoA. In addition, PKS3 also afforded a hexaketide pyrone (i.e. the precursor of aloenin), a heptaketide 6-(2-acetyl-3,5-dihydroxybenzyl)-4-hydroxy-2-pyrone, a novel heptaketide 6-(2-(2,4-dihydroxy-6-methylphenyl)-2-oxoethyl)-4-hydroxy-2-pyrone and octaketides SEK4/SEK4b. This is the first demonstration of the enzymatic formation of the precursors of the pharmaceutically important aloesin and aloenin by a wild-type PKS obtained from A. arborescens. Interestingly, the aloesone-forming activity was maximum at 50 degrees C, and the novel heptaketide pyrone was non-enzymatically converted to aloesone. In PKS3, the active-site residue 207, which is crucial for controlling the polyketide chain length depending on the steric bulk of the side chain, is uniquely substituted with Ala. Site-directed mutagenesis demonstrated that the A207G mutant dominantly produced the octaketides SEK4/SEK4b, whereas the A207M mutant yielded a pentaketide 5,7-dihydroxy-2-methylchromone. PMID:19348024

  2. Determination of aloenin, barbaloin and isobarbaloin in aloe species by micellar electrokinetic chromatography.

    Science.gov (United States)

    Kuzuya, H; Tamai, I; Beppu, H; Shimpo, K; Chihara, T

    2001-03-01

    Aloenin, barbaloin and isobarbaloin in JP Aloe, Aloe barbadensis (Aloe vera) and Aloe arborescens Miller var. natalensis Berger (Aloe arborescens Miller) were determined by micellar electrokinetic chromatography (MEKC) with 50 mM sodium dodecyl sulfate. Aloenin, barbaloin and isobarbaloin were well separated by MEKC and as little as 5.5 pg/11 nl of the three compounds could be detected. The determination took around 14 min. PMID:11254203

  3. Immunochemical distinction of Aloe vera, A. arborescens, and A. chinensis gels.

    Science.gov (United States)

    Yagi, A; Tsunoda, M; Egusa, T; Akasaki, K; Tsuji, H

    1998-04-01

    Verectin antiserum raised in white rabbits was immunoprecipitated with the Aloe vera nondialysable fraction. Analysis of the immunoprecipitation revealed that verectin accounted for about 1.25% of the total proteins in the nondialysable fraction of Aloe vera gel. The verectin antibody showed differential immunoreactivities against nondialysable fractions of A. arborescens, A. chinensis, and A. vera: 1) an immunopreciptin line was formed against the fraction of A. vera, but not against those of A. arborescens and A. chinensis gel in an Ouchterlony double immunodiffusion test and 2) an immunopositive band was detected in the A. vera and A. chinensis nondialysable fractions but not in that of A. arborescens in immunoblotting. These findings indicate that the verectin antibody can be used to distinguish Aloe materials. PMID:9581527

  4. Purification and characterization of two lectins from Aloe arborescens Mill.

    Science.gov (United States)

    Suzuki, I; Saito, H; Inoue, S; Migita, S; Takahashi, T

    1979-01-01

    Two lectins have been isolated from leaves of Aloe arborescens Mill by salt precipitation, pH-dependent fractionation and gel filtration. One lectin (P-2) has a molecular weight of approximately 18,000, consists of two subunits (alphabeta) and contains more than 18% by weight of neutral carbohydrate. The smaller subunit (alpha) has a molecular weight of approximately 7,500 and the larger subunit (beta) a molecular weight of approximately 10,500. The other lectin (S-1) has a molecular weight of approximately 24,000, consists of two subunits (gamma2) with a molecular weight of approximately 12,000 and contains more than 50% by weight of neutral carbohydrate. An interesting feature of the amino acid compositions of these lectins is the high proportion of acidic amino acids, such as aspartic acid and glutamic acid, and the low proportion of methionine and histidine. S-1 has a strong hemagglutinating activity. On the other hand, P-2 has not only hemagglutinating activity but also mitogenic activity on lymphocytes, precipitate-forming reactivity with serum proteins, one of which is alpha2-macroglobulin, and complement C3 activating activity via the alternate pathway. PMID:104986

  5. Candelabra aloe (Aloe arborescens) in the therapy and prophylaxis of upper respiratory tract infections: traditional use and recent research results.

    Science.gov (United States)

    Bastian, Petra; Fal, Andrzej M; Jambor, Jerzy; Michalak, Anna; Noster, Britta; Sievers, Hartwig; Steuber, Anke; Walas-Marcinek, Natalia

    2013-02-01

    Aloe arborescens (Candelabra Aloe) has been used in the treatment of upper respiratory tract infections in Central and Eastern European countries for many decades. Originally introduced to support the healing and recovery in cornea transplant patients, aqueous A. arborescens extracts soon became popular in the treatment of upper respiratory tract infections with a focus on toddlers and children. Recent preclinical and clinical data show that immunomodulatory, antiinflammatory, and antiviral effects contribute to its therapeutic efficacy. Based on its well documented, longstanding traditional use and its excellent safety and tolerability, A. arborescens may be considered a valuable addition to the spectrum of herbal medicinal products for the treatment and prophylaxis of upper respiratory tract infections, in particular common cold, in adults and children. PMID:23361849

  6. Effects of aloe arborescens ingestion on azoxymethane-induced intestinal carcinogenesis and hematological and biochemical parameters of male F344 rats.

    Science.gov (United States)

    Shimpo, Kan; Beppu, Hidehiko; Chihara, Takeshi; Kaneko, Takaaki; Shinzato, Masanori; Sonoda, Shigeru

    2006-01-01

    We examined the modifying effect of freeze-dried whole-leaf Aloe arborescens Miller var. natalensis Berger (Kidachi aloe in Japan; designated as 'ALOE') on azoxymethane (AOM)-induced intestinal carcinogenesis in rats. Male F344 rats (4 weeks old) were fed basal diet or experimental diet containing 0.2% or 1% ALOE for 28 weeks. Starting two weeks later, the animals received subcutaneous injections of AOM once weekly for 10 weeks. The incidence of colorectal adenocarcinomas in the 0.2% (but not 1%) ALOE group showed a strong tendency for decrease (p = 0.056) from the control group. Further, the adenocarcinoma incidence in the entire intestine (small and large intestines) in the 0.2% ALOE group was significantly (p = 0.024) decreased compared to the control value. However, there were no significant differences in tumor multiplicities of colorectal or entire intestines among the 3 groups. In addition, we also studied the safety of long-term ingestion of ALOE as a health food or natural thickening stabilizer. Rats were fed the basal diet or 1% ALOE diet for 35 weeks without AOM treatment. Feeding with 1% ALOE did not affect most hematological and serum biochemical parameters in the rats. These results indicate that a low level of ALOE ingestion might have a mild suppressive effect on intestinal tumor growth without harmful side effects. PMID:17250432

  7. Biologically active constituents of leaves and roots of Aloe arborescens var. natalensis.

    Science.gov (United States)

    Hirata, T; Suga, T

    1977-01-01

    Several biologically active substances, such as aloenin (1), magnesium lactate, aloe-emodin (4), barbaloin (5), and succinic acid, were found to be contained in the leaf juice of Aloe arborescens Mill. var. natalensis Berger, which has widely been used in domestic medicines. Aloenin (1) and magnesium lactate were elucidated to exhibit an inhibitory action on the gastric juice secretion of rats. Various constituents other than the above bioactive substances were found in the leaves and the roots of the plant. PMID:145111

  8. TECHNOLOGICAL ASPECTS CONCERNING PRODUCTION ON ASEXUAL TRACK OF ORNAMENTAL CULTURE OF ALOE ARBORESCENS

    Directory of Open Access Journals (Sweden)

    Mădălina Doltu

    2012-12-01

    Full Text Available Research conducted in culture of Aloe arborescens Mill., in conditions of protected area (greenhouse, had to watch some of technological aspects to obtain some in pot ornamentals plants, competitive plants for european market. Experience has included plants of Aloe arborescens Mill., aged 1-5 years, obtained by vegetative multiplying, asexual. Production technology was applied to aloe plants (multiplying, transplanting, maintenance, taking into account the ecological requirements of specie and possibilities of using automated artificial factors influencing microclimate (shading, ventilation, cooling of production space. Researches has established technological aspects concerning production of plants, to satisfy requirements of specie, for obtained some specimens by superior decorative quality. The results of experienced technology indicate quality of morphological characters, growth increases important of decorative elements (height, leaves, shoots, appearance of flowering at plants aged two years. Culture of Aloe arborescens Mill. in pot, can be practiced all year, just in conditions of protected areas. This culture, realized in the purpose for obtain decorative plants, is a valuable activity of horticulture.

  9. Technology of eye drops containing aloe (Aloe arborescens Mill.--Liliaceae) and eye drops containing both aloe and neomycin sulphate.

    Science.gov (United States)

    Kodym, A; Marcinkowski, A; Kukuła, H

    2003-01-01

    Eye drops made of aloe are a sterile, aqueous extract of fresh leaves of Aloe arborescens Mill., containing necessary additives and neomycin sulphate. The aim of the studies was to establish the technology of eye drops containing biologically active aloe substances and those containing both chemical constituents of aloe and neomycin sulphate. Within the studies, the formulary content and the way of preparing eye drops were determined, criteria were defined and methods of qualitative assessment of drops were proposed. On the basis of the proposed analytical methods, the physicochemical and microbiological stability of the eye drops stored at a temperature of 20-25 degrees C was studied. As the criteria of qualitative assessment of the eye drops, the following analyses were considered: sterility, appearance of the eye drops (clarity), pH, osmotic pressure, density, viscosity, TLC analysis, content of aloenin and aloin, studies of anti-microbial activity of neomycin in the drops, and preservative efficiency of thiomersal in the eye drops. The studies showed that the additives such as: sodium chloride, benzalkonium chloride, chlorhexidine diacetate and digluconate, phenylmercuric borate and Nipagins M and P could not be used to prepare the eye drops because they were involved in pharmaceutical interactions with chemical constituents of aloe in the eye drops. The eye drops containing: aqueous extract of fresh leaves of aloe, boric acid, thiomersal, sodium pyrosulphite, disodium EDTA, beta-phenylethyl alcohol and neomycin sulphate, both freshly prepared and after two years of storage, met the requirements of the Polish Pharmacopoeia (PPh V) mentioned in the monograph Guttae ophthalmicae. They were sterile, clear, their osmotic pressure approximated the osmotic pressure of lacrimal fluid and they were characterized by appropriate pH. Aloenin in the drops was much more stable than aloin. Neomycin after two years of storage retained almost 98% of its starting antimicrobial

  10. Cloning and functional analysis of a novel aldo-keto reductase from Aloe arborescens.

    Science.gov (United States)

    Morita, Hiroyuki; Mizuuchi, Yuusuke; Abe, Tsuyoshi; Kohno, Toshiyuki; Noguchi, Hiroshi; Abe, Ikuro

    2007-12-01

    A novel aldo-keto reductase (AKR) was cloned and sequenced from roots of Aloe arborescens by a combination of RT-PCR using degenerate primers based on the conserved sequences of plant polyketide reductases (PKRs) and cDNA library screening by oligonucleotide hybridization. A. arborescens AKR share similarities with known plant AKRs (40-66% amino acid sequence identity), maintaining most of the active-site residues conserved in the AKR superfamily enzymes. Interestingly, despite the sequence similarity with PKRs, recombinant enzyme expressed in Escherichia coli did not exhibit any detectable PKR activities. Instead, A. arborescens AKR catalyzed NADPH-dependent reduction of various carbonyl compounds including benzaldehyde and DL-glyceraldehyde. Finally, a homology model on the basis of the crystal structure of Hordeum vulgare AKR predicted the active-site architecture of the enzyme. PMID:18057709

  11. Streptomyces zhaozhouensis sp. nov., an actinomycete isolated from candelabra aloe (Aloe arborescens Mill).

    Science.gov (United States)

    He, Hairong; Liu, Chongxi; Zhao, Junwei; Li, Wenjun; Pan, Tong; Yang, Lingyu; Wang, Xiangjing; Xiang, Wensheng

    2014-04-01

    A novel endophytic actinomycete, designated strain NEAU-LZS-5(T), was isolated from the leaf of candelabra aloe (Aloe arborescens Mill) and characterized using a polyphasic approach. Analysis of the 16S rRNA gene sequence showed that strain NEAU-LZS-5(T) belongs to the genus Streptomyces and exhibited 99.51 and 97.37 % similarity to Streptomyces sedi YIM 65188(T) and Streptomyces specialis GW41-1564(T), respectively, whereas low similarity values (<97 %) distinguished strain NEAU-LZS-5(T) from all other species of the genus Streptomyces with validly published names. Two tree-making algorithms also supported the position that strain NEAU-LZS-5(T) formed a distinct clade with Streptomyces sedi YIM 65188(T) and Streptomyces specialis GW41-1564(T). However, levels of DNA-DNA relatedness between strain NEAU-LZS-5(T) and Streptomyces sedi YIM 65188(T) and Streptomyces specialis GW41-1564(T) were 45.59 and 31.90 %, respectively. A comparative study between strain NEAU-LZS-5(T) and the type strains of closest related species of the genus Streptomyces revealed that it differed from them in morphological, physiological and biochemical characteristics. Therefore, strain NEAU-LZS-5(T) represents a novel species of the genus Streptomyces, for which the name Streptomyces zhaozhouensis sp. nov. is proposed. The type strain is NEAU-LZS-5(T) ( = CGMCC 4.7095(T) = DSM 42101(T)). PMID:24368691

  12. Isolation of cDNA for an NADP-malic enzyme from Aloe arborescens.

    Science.gov (United States)

    Honda, H; Shimada, H; Akagi, H

    1997-12-31

    NADP-malic enzyme catalyzes the reaction of decarboxylation from malate. In CAM plants, functions of this enzyme diverged to include both photosynthetic and non-photosynthetic roles. A full length cDNA for an NADP-malic enzyme was isolated from an 'obligate' CAM plant aloe (Aloe arborescens). The cDNA contains an ORF encoding 592 amino acid residues, whose sequence is highly homologous to the known plant NADP-malic enzymes. This gene is constitutively expressed in all organs in a low level. The amount of the transcript exhibited no diurnal variation, suggesting that this gene is not involved in photosynthetic functions. PMID:9501996

  13. Inhibition of azoxymethane-induced DNA adduct formation by Aloe arborescens var. natalensis.

    Science.gov (United States)

    Shimpo, Kan; Chihara, Takeshi; Beppu, Hidehiko; Ida, Chikako; Kaneko, Takaaki; Hoshino, Motoyuki; Kuzuya, Hiroshi

    2003-01-01

    To clarify the possible mechanisms of inhibition of azoxymethane (AOM)-induced aberrant crypt foci (ACF) in the rat colorectum by freeze-dried whole leaves of Aloe arborescens var. natalensis (Kidachi aloe) (hereinafter referred to as ALOE) and commercial crude aloin (Sigma A-0451; from Curacao aloe) (hereinafter ALOIN), we studied the effects of ALOE and ALOIN on the formation of AOM-induced DNA adducts (O6-methylguanine; O6-MeG) in rats. Male F344 rats (4 weeks old) were fed a basal diet, or experimental diets containing 5%ALOE or 0.25%ALOIN for 5 weeks. All rats were injected s.c. twice with 15 mg/kg AOM, once at the end of week 1, and once at the end of week 2. The animals were sacrificed 6 hours after the second injection to analyze DNA adducts (O6-MeG) in the colorectum. Dietary administration of ALOE significantly inhibited the O6-MeG levels (50% reduction) compared with controls, whereas the O6-MeG levels in the ALOIN-fed rats showed a tendency to decrease (by 30%), although not significantly. In this study, we also measured the enzyme activity and mRNA level of cytochrome (CYP) 2E1, known to be responsible for the activation of AOM, in rat liver. ALOE-fed rats showed significantly reduced CYP2E1 enzymatic activity (27% reduction) compared with controls. On the other hand, the activity in ALOIN-fed rats tended to decrease by 11%, although not significantly. The CYP2E1 mRNA levels in ALOE- and ALOIN-fed rats were slightly reduced (9.7% and 5.2%, respectively). These results may explain, at least in part, the previously observed inhibitory effects of ALOE and ALOIN, especially ALOE on AOM-induced ACF formation in the rat colorectum. PMID:14507246

  14. Aloe arborescens Extract Protects IMR-32 Cells against Alzheimer Amyloid Beta Peptide via Inhibition of Radical Peroxide Production.

    Science.gov (United States)

    Clementi, Maria Elisabetta; Tringali, Giuseppe; Triggiani, Doriana; Giardina, Bruno

    2015-11-01

    Aloe arborescens is commonly used as a pharmaceutical ingredient for its effect in burn treatment and ability to increase skin wound healing properties. Besides, it is well known to have beneficial phytotherapeutic, anticancer, and radio-protective properties. In this study, we first provided evidence that A. arborescens extract protects IMR32, a neuroblastoma human cellular line, from toxicity induced by beta amyloid, the peptide responsible for Alzheimer's disease. In particular, pretreatment with A. arborescens maintains an elevated cell viability and exerts a protective effect on mitochondrial functionality, as evidenced by oxygen consumption experiments. The protective mechanism exerted by A. arborescens seems be related to lowering of oxidative potential of the cells, as demonstrated by the ROS measurement compared with the results obtained in the presence of amyloid beta (1-42) peptide alone. Based on these preliminary observations we suggest that use ofA. arborescens extract could be developed as agents for the management of AD. PMID:26749845

  15. Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin.

    Science.gov (United States)

    Shimpo, Kan; Ida, Chikako; Chihara, Takeshi; Beppu, Hidehiko; Kaneko, Takaaki; Kuzuya, Hiroshi

    2002-08-01

    The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chemopreventive agents against tumour promotion. PMID:12203274

  16. Antifungal activity evaluation of Aloe arborescens dry extract against trichosporon genus yeasts

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    João Ricardo Bueno de Morais Borba

    2014-10-01

    Full Text Available The objective of this study was to investigate the antifungal activity of Aloe arborescens dry extract against Trichosporon genus yeast species. Extraction was carried out by means of a longitudinal incision in fresh leaves, which were collected on a vat, and the total volume was frozen and subsequently lyophilized. Then, 40 mg of the dry extract was dissolved in DMSO by gentle inversion in order to obtain a solution whose concentration was 4000 µg mL-1. This solution became limpid and slightly yellowish because the pigment of the latex was attenuated. It was performed serial dilutions from 2,000 to 15.625 µg mL-1 with RPMI-1640 broth. There was already no pigment in the first dilution of 2000 μg mL-1. It was analyzed fifteen strains of Trichosporon spp., and Candida albicans ATCC 10231 was used as control strain. We carried out the reading of microplates in the ELISA reader device at a wavelength of 530 nm, after incubation for 24 and 48 hours, and it was determinated the Minimum Inhibitory Concentration (MIC. The MIC50 value obtained for all Trichosporon species and for C. albicans was 500 µg mL-1. As a result, we concluded that Aloe arborescens dry extract has antifungal activity against Trichosporon yeasts.

  17. Topical Aloe Vera (Aloe barbadensis Miller) Extract Does Not Accelerate the Oral Wound Healing in Rats.

    Science.gov (United States)

    Coelho, Fernanda Hack; Salvadori, Gabriela; Rados, Pantelis Varvaki; Magnusson, Alessandra; Danilevicz, Chris Krebs; Meurer, Luise; Martins, Manoela Domingues

    2015-07-01

    The effect of topical application of Aloe Vera (Aloe barbadensis Miller) extract was assessed on the healing of rat oral wounds in an in vivo model using 72 male Wistar rats divided into three groups (n = 24): control, placebo and Aloe Vera (0.5% extract hydroalcoholic). Traumatic ulcers were caused in the dorsum of the tongue using a 3-mm punch tool. The Aloe Vera and placebo group received two daily applications. The animals were sacrificed after 1, 5, 10 and 14 days. Clinical analysis (ulcer area and percentage of repair) and histopathological analysis (degree of re-epithelialization and inflammation) were performed. The comparison of the differences between scores based on group and experimental period, both in quantitative and semi-quantitative analyses, was performed using the Kruskal-Wallis test. The significance level was 5%. On day 1, all groups showed predominantly acute inflammatory infiltrate. On day 5, there was partial epithelialization and chronic inflammatory infiltrate. On the days 10 and 14 total repair of ulcers was observed. There was no significant difference between groups in the repair of mouth ulcers. It is concluded that treatment using Aloe Vera as an herbal formulation did not accelerate oral wound healing in rats.

  18. The Relation between Photosynthesis, Respiration, and Crassulacean Acid Metabolism in Leaf Slices of Aloe arborescens Mill.

    Science.gov (United States)

    Denius, H R; Homann, P H

    1972-06-01

    Leaves and leaf slices from Aloe arborescens Mill. were used to study the interrelations between Crassulacean acid metabolism, photosynthesis, and respiration. Oxygen exchange of leaf slices was measured polarographically. It was found that the photosynthetic utilization of stored malic acid resulted in a net evolution of oxygen. This oxygen production, and the decrease in acid content of the leaf tissue, were completely inhibited by amytal, although the rate of respiratory oxygen uptake was hardly affected by the presence of this inhibitor of mitochondrial electron transport. Other poisons of respiration (cyanide) and of the tricarboxylic acid cycle (trifluoroacetate, 2-diethyl malonate) also were effective in preventing acid-dependent oxygen evolution. It is concluded that the mobilization of stored acids during light-dependent deacidification of the leaves depends on the operation of the tricarboxylic acid cycle and of the electron transport of the mitochondria.A comparison of enzyme activities in extracts from Aloe leaves and from other plants and studies of leaf anatomy and chloroplast morphology revealed typical characteristics of C(3)-, as well as C(4)-, plants in Aloe. PMID:16658075

  19. Aroma chemicals isolated and identified from leaves of Aloe arborescens Mill. Var. Natalensis Berger.

    Science.gov (United States)

    Umano, K; Nakahara, K; Shoji, A; Shibamoto, T

    1999-09-01

    Extracts from leaves of aloe (Aloe arborescens Mill. var. natalensis Berger) were obtained using two methods: steam distillation under reduced pressure followed by dichloromethane extraction (DRP) and simultaneous purging and extraction (SPE). A total of 123 aroma chemicals were identified in the extracts obtained by both methods using gas chromatography and gas chromatography/mass spectrometry. There were 42 alcohols, 23 terpenoids, 21 aldehydes, 9 esters, 8 ketones, 6 acids, 5 phenols, and 9 miscellaneous compounds. The major aroma constituents of this extract by DRP were (Z)-3-hexenol (29.89%), (Z)-3-hexenal (18.86%), (E)-hexenal (7.31%), 4-methyl-3-pentenol (5.66%), and butanol (4.29%). The major aroma constituents of this extract by SPE were (E)-2-hexenal (45.46%), (Z)-3-hexenal (32.12%), hexanal (9.14%), (Z)-3-hexenol (1.60%), and 3-pentanone (1.41%). Terpenoids were also found as one of the major constituents. The fresh green note of aloe leaves is due to the presence of these C(6) alcohols and aldehydes as well as terpenoids. PMID:10552708

  20. Biopharmaceutical assessment of eye drops containing aloe (Aloe arborescens Mill.) and neomycin sulphate.

    Science.gov (United States)

    Kodym, Anna; Grześkowiak, Edmund; Partyka, Danuta; Marcinkowski, Andrzej; Kaczyńska-Dyba, Ewelina

    2002-01-01

    The subject of the studies was eye drops made of aloe, containing the group of aloe chemical substances of anti-inflammatory use and neomycin sulphate. The aim of the studies was to evaluate the permeability of biologically active aloe substances, determined as aloenin, through synthetic lipophilic and hydrophilic membranes in a standard perfusion apparatus and in vitro verification of the transport possibilities of these substances through the isolated cornea of pig's eye. The permeability process of biologically active aloe substances determined as aloenin, through synthetic lipophilic and hydrophilic membranes, was analyzed using the first-order kinetics. Estimated quotas of permeability rate constant show that the investigated chemical compounds of aloe, included in the eye drops, diffused through the applied membranes. The studies of permeability through isolated pig's cornea proved that biologically active aloe substances could not overcome this biological barrier. On the basis of biopharmaceutical studies it can be concluded that the eye drops containing aloe and neomycin sulphate, due to the lack of permeating abilities through the eye cornea, should be particularly useful in the treatment of inflammations and infections of external parts of the eye, such as conjuctiva, eyelid edges, lacrimal sac and cornea. PMID:12230244

  1. Structural Modifications of Fructans in Aloe barbadensis Miller (Aloe Vera) Grown under Water Stress

    Science.gov (United States)

    Salinas, Carlos; Cardemil, Liliana

    2016-01-01

    Aloe barbadensis Miller (Aloe vera) has a Crassulaceae acid metabolism which grants the plant great tolerance to water restrictions. Carbohydrates such as acemannans and fructans are among the molecules responsible for tolerating water deficit in other plant species. Nevertheless, fructans, which are prebiotic compounds, have not been described nor studied in Aloe vera, whose leaf gel is known to possess beneficial pharmaceutical, nutritional and cosmetic properties. As Aloe vera is frequently cultivated in semi-arid conditions, like those found in northern Chile, we investigated the effect of water deficit on fructan composition and structure. For this, plants were subjected to different irrigation regimes of 100%, 75%, 50% and 25% field capacity (FC). There was a significant increase in the total sugars, soluble sugars and oligo and polyfructans in plants subjected to water deficit, compared to the control condition (100% FC) in both leaf tips and bases. The amounts of fructans were also greater in the bases compared to the leaf tips in all water treatments. Fructans also increase in degree of polymerization with increasing water deficit. Glycosidic linkage analyses by GC-MS, led to the conclusion that there are structural differences between the fructans present in the leaves of control plants with respect to plants irrigated with 50% and 25% FC. Therefore, in non-stressed plants, the inulin, neo-inulin and neo-levan type of fructans predominate, while in the most stressful conditions for the plant, Aloe vera also synthesizes fructans with a more branched structure, the neofructans. To our knowledge, the synthesis and the protective role of neo-fructans under extreme water deficit has not been previously reported. PMID:27454873

  2. Structural Modifications of Fructans in Aloe barbadensis Miller (Aloe Vera) Grown under Water Stress.

    Science.gov (United States)

    Salinas, Carlos; Handford, Michael; Pauly, Markus; Dupree, Paul; Cardemil, Liliana

    2016-01-01

    Aloe barbadensis Miller (Aloe vera) has a Crassulaceae acid metabolism which grants the plant great tolerance to water restrictions. Carbohydrates such as acemannans and fructans are among the molecules responsible for tolerating water deficit in other plant species. Nevertheless, fructans, which are prebiotic compounds, have not been described nor studied in Aloe vera, whose leaf gel is known to possess beneficial pharmaceutical, nutritional and cosmetic properties. As Aloe vera is frequently cultivated in semi-arid conditions, like those found in northern Chile, we investigated the effect of water deficit on fructan composition and structure. For this, plants were subjected to different irrigation regimes of 100%, 75%, 50% and 25% field capacity (FC). There was a significant increase in the total sugars, soluble sugars and oligo and polyfructans in plants subjected to water deficit, compared to the control condition (100% FC) in both leaf tips and bases. The amounts of fructans were also greater in the bases compared to the leaf tips in all water treatments. Fructans also increase in degree of polymerization with increasing water deficit. Glycosidic linkage analyses by GC-MS, led to the conclusion that there are structural differences between the fructans present in the leaves of control plants with respect to plants irrigated with 50% and 25% FC. Therefore, in non-stressed plants, the inulin, neo-inulin and neo-levan type of fructans predominate, while in the most stressful conditions for the plant, Aloe vera also synthesizes fructans with a more branched structure, the neofructans. To our knowledge, the synthesis and the protective role of neo-fructans under extreme water deficit has not been previously reported.

  3. Structural Modifications of Fructans in Aloe barbadensis Miller (Aloe Vera) Grown under Water Stress.

    Science.gov (United States)

    Salinas, Carlos; Handford, Michael; Pauly, Markus; Dupree, Paul; Cardemil, Liliana

    2016-01-01

    Aloe barbadensis Miller (Aloe vera) has a Crassulaceae acid metabolism which grants the plant great tolerance to water restrictions. Carbohydrates such as acemannans and fructans are among the molecules responsible for tolerating water deficit in other plant species. Nevertheless, fructans, which are prebiotic compounds, have not been described nor studied in Aloe vera, whose leaf gel is known to possess beneficial pharmaceutical, nutritional and cosmetic properties. As Aloe vera is frequently cultivated in semi-arid conditions, like those found in northern Chile, we investigated the effect of water deficit on fructan composition and structure. For this, plants were subjected to different irrigation regimes of 100%, 75%, 50% and 25% field capacity (FC). There was a significant increase in the total sugars, soluble sugars and oligo and polyfructans in plants subjected to water deficit, compared to the control condition (100% FC) in both leaf tips and bases. The amounts of fructans were also greater in the bases compared to the leaf tips in all water treatments. Fructans also increase in degree of polymerization with increasing water deficit. Glycosidic linkage analyses by GC-MS, led to the conclusion that there are structural differences between the fructans present in the leaves of control plants with respect to plants irrigated with 50% and 25% FC. Therefore, in non-stressed plants, the inulin, neo-inulin and neo-levan type of fructans predominate, while in the most stressful conditions for the plant, Aloe vera also synthesizes fructans with a more branched structure, the neofructans. To our knowledge, the synthesis and the protective role of neo-fructans under extreme water deficit has not been previously reported. PMID:27454873

  4. Physicochemical and microbiological properties as well as stability of ointments containing aloe extract (Aloe arborescens Mill.) or aloe extract associated to neomycin sulphate.

    Science.gov (United States)

    Kodym, A; Bujak, T

    2002-12-01

    The aim of the study was to work out methods of quality assessment of ointments containing dry extract from fresh leaves of Aloe arborescens Mill. (Lilliaceae) and also of ointments containing both of dry extract and neomycin sulphate. The stability of the ointments, stored at 20 degrees C, was studied and the following criteria were considered: chromatographic analysis (TLC), pH of the ointments, the content of the substances in the dry extract converted to aloenin, the content of aloenin and aloin, anti-microbial activity of neomycin in the ointments, the size of the particles of the dry extract and of neomycin sulphate in the ointment suspension and the sterility of the ointments. After two years of storage at 20 degrees C, the ointments prepared with the anhydrous lipophilic base, did not change their physicochemical characteristics and neomycin in those ointments retained almost 100% of starting anti-microbial activity. Water or propylene glycol significantly decreased the stability of the biologically active substances of the dry extract in the ointments. Besides, in the ointments containing the dry extract and neomycin sulphate, the presence of water or propylene glycol induced degradation of the biologically active substances of the dry extract and a decrease in the anti-microbial activity of neomycin in the ointments. Considering the physicochemical and microbiological stability, the most advisable base for the ointments with aloe and neomycin sulphate was composed of white vaseline, liquid paraffin, solid paraffin, cholesterol. PMID:12561247

  5. Effect of ultrasonic exposure on Ca2+-ATPase activity in plasma membrane from Aloe arborescens callus cells.

    Science.gov (United States)

    Liu, Yiyao; Yang, Hong; Takatsuki, Hideyo; Sakanishi, Akio

    2006-04-01

    We investigated the effect of ultrasound on plasma membrane (PM) Ca2+-ATPase activity of Aloe arborescens callus cells in solid culture. The calluses were exposed by a 20 kHz digital sonifier at the powers of 2 and 10 W from the effective exposure times of 2-10 s. PM Ca2+-ATPase activity was almost significantly higher at 2 W both in continuous wave and 10% duty cycle than that of the control (no ultrasound) at effective exposure times of 5 and 10 s. However, its activity decreased at 10 W in continuous wave exposure. It is possible that the PM Ca2+-ATPase configuration or structure may be partly damaged by high-energy ultrasound at 10 W. Our results showed that low-energy ultrasound exposure was a useful physical field to stimulate A. arborescens callus cells to adapt environmental stress through PM Ca2+-ATPase activity increase. PMID:15936236

  6. Chemopreventive effects of Aloe arborescens on N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters.

    Science.gov (United States)

    Furukawa, Fumio; Nishikawa, Akiyoshi; Chihara, Takeshi; Shimpo, Kan; Beppu, Hidehiko; Kuzuya, Hiroshi; Lee, In Seon; Hirose, Masao

    2002-04-25

    The modification effects of freeze-dried aloe (Aloe arborescens) whole leaf powder during the initiation phase of carcinogenesis were investigated in hamsters treated with N-nitrosobis(2-oxopropyl)amine (BOP). Female Syrian hamsters were given four weekly subcutaneous injections of BOP at a dose of 10mg/kg and then given 0, 1 or 5% aloe in their diet for 5 weeks. At week 54 of the experiment, all surviving animals were sacrificed and development of neoplastic and preneoplastic lesions was assessed histopathologically. The incidences of pancreatic adenocarcinomas, atypical hyperplasias or total atypical hyperplasias plus adenocarcinomas were significantly (Paloe, and that of adenocarcinomas were also significantly (Paloe as compared to the BOP alone group. Multiplicities of pancreatic adenocarcinomas, atypical hyperplasias or total lesions were also significantly (Paloe group than with the BOP alone. Quantitative data for neoplastic lesions in the lung, liver, gall bladder, kidney and urinary bladder of hamsters were not significantly different among the three groups. In a satellite experiment, pretreatment with aloe significantly (Paloe prevents BOP-induced pancreatic neoplasia in hamsters in relation to decreased DNA adduct formation in the target tissue. PMID:11867195

  7. Evaluation of antioxidant potential of aloe vera (Aloe barbadensis miller) extracts.

    Science.gov (United States)

    Hu, Yun; Xu, Juan; Hu, Qiuhui

    2003-12-17

    The polysaccharide and flavonoid concentrations of two-, three-, and four-year-old Aloe vera were determined, and their antioxidant activities were evaluated compared to BHT and alpha-tocopherol by the DPPH radical scavenging method and the linoleic acid system at 100 microg of soluble solids per mL of ethanol. The results showed that three-year-old Aloe vera contained significantly higher levels of polysaccharides and flavonoids than two- and four-year-old Aloe vera, and no significant differences in flavonoid levels were found between three- and four-year-old Aloe vera. All the aloe extracts showed significant antioxidant activity. The antioxidant activity of Aloe vera extracts and reference compounds followed the order: three-year-old Aloe vera > BHT > four-year-old Aloe vera > alpha-tocopherol > two-year-old Aloe vera. The three-year-old extract exhibited the strongest radical scavenging activity of 72.19%, which is significantly higher than that of BHT at 70.52% and alpha-tocopherol at 65.20%. These data suggest that the growth stage plays a vital role in the composition and antioxidant activity of Aloe vera. PMID:14664546

  8. Caracterización morfoanatómica comparativa entre Aloe vera (L.) Burm. F., Aloe arborescens Mill., Aloe saponaria Haw. y Aloe ciliaris Haw. (Aloeaceae) : Comparative morphoanatomical characterization between Aloe vera (L.) Burm. F., Aloe arborescens Mill., Aloe saponaria Haw. and Aloe ciliaris Haw. (Aloaceae)

    OpenAIRE

    Stella Maris Carpano; María Teresa Castro; Etile Dolores Spegazzini

    2009-01-01

    Aloe vera (L.) Burm. F. (= Aloe barbadensis Miller) conhecida como "a planta da imortalidade" no antigo Egito é utilizada em fitoterapia como humectante, antibacteriana, antifúngica, antiviral e antioxidante. Com a finalidade de contribuir para identificação da droga vegetal, foram realizados estudos morfoanatômicos da folha. A utilização de plantas com características terapêuticas reconhecidas determina que, por analogia, popularmente sejam utilizadas com a mesma finalidade outras espécies d...

  9. [Studies on chemical protectors against radiation. XXXI. Protection effects of Aloe arborescens on skin injury induced by X-irradiation].

    Science.gov (United States)

    Sato, Y; Ohta, S; Shinoda, M

    1990-11-01

    Protective effects of Aloe arborescens (AA) on mouse skin injury induced by soft X-irradiation were examined. The mechanisms on radiation protection by measuring scavenge activity of activated oxygen, protective effects of nucleic acid, induction of antioxidative protein and so on were further investigated. Consequently a significant protective effect of skin injury was observed in AA S6-3-b. As the mechanisms of radiation protection in AA, the following matters were found. AA S6-3-b showed scavenge activity of hydroxyl radicals generated by Haber-Weiss reaction. AA S6-3-b suppressed the changes of activity in superoxide dismutase and glutathione peroxidase at 7d after soft X-irradiation. Metallothionein was induced in the skin and liver against normal mice at 24 h after administration of AA S6-3-b. PMID:2082014

  10. Structural insight into chain-length control and product specificity of pentaketide chromone synthase from Aloe arborescens.

    Science.gov (United States)

    Morita, Hiroyuki; Kondo, Shin; Oguro, Satoshi; Noguchi, Hiroshi; Sugio, Shigetoshi; Abe, Ikuro; Kohno, Toshiyuki

    2007-04-01

    The crystal structures of a wild-type and a mutant PCS, a novel plant type III polyketide synthase from a medicinal plant, Aloe arborescens, were solved at 1.6 A resolution. The crystal structures revealed that the pentaketide-producing wild-type and the octaketide-producing M207G mutant shared almost the same overall folding, and that the large-to-small substitution dramatically increases the volume of the polyketide-elongation tunnel by opening a gate to two hidden pockets behind the active site of the enzyme. The chemically inert active site residue 207 thus controls the number of condensations of malonyl-CoA, solely depending on the steric bulk of the side chain. These findings not only provided insight into the polyketide formation reaction, but they also suggested strategies for the engineered biosynthesis of polyketides. PMID:17462571

  11. Studies on chemical protectors against radiation, 31; Protection effects of Aloe arborescens on skin injury induced by X-irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Yushi; Ohta, Setsuko; Shinoda, Masato (Hoshi Univ., Tokyo (Japan))

    1990-11-01

    Protective effects of Aloe arborescens (AA) on mouse skin injury induced by soft X-irradiation were examined. The mechanisms on radiation protection by measuring scavenge activity of activated oxygen, protective effects of nucleic acid, induction of antioxidative protein and so on were further investigated. Consequently a significant protective effect of skin injury was observed in AA S6-3-b. As the mechanisms of radiation protection in AA, the following matters were found. AA S6-3-b showed scavenge activity of hydroxyl radicals generated by Haber-Weiss reaction. AA S6-3-b suppressed the changes of activity in superoxide dismutase and gluthathione peroxidase at 7d after soft X-irradiation. Metallothionein was induced in the skin and liver against normal mice at 24 h after administration of AA S6-3-b. (author).

  12. Evaluation of in vitro and in vivo antioxidant potential of polysaccharides from Aloe vera (Aloe barbadensis Miller) gel.

    Science.gov (United States)

    Kaithwas, Gaurav; Singh, Prashant; Bhatia, Daksh

    2014-04-01

    In the present study, the antioxidant activity of the polysaccharides from aloe vera (Aloe barbadensis Miller) gel was evaluated, in vitro by five established methods, 1,1-diphenyl-2-picrylhydrazyl (DPPH(-)) radical scavenging, nitric oxide (NO) scavenging, hydrogen peroxide scavenging, superoxide radical (O(-2)) scavenging and reducing power assay, and in vivo against doxorubicin (DOX)-induced myocardial oxidative stress (OS) in albino wistar rats. The polysaccharides exhibited significant inhibitory activity against DPPH(-), superoxide, NO and hydrogen peroxide scavenging assay with significant reducing activity at all concentrations used. DOX-induced (7.5 mg/kg, intravenously) cardiotoxicity manifested biochemically by a significant decrease in blood and tissue glutathione (GSH) along with elevated levels of serum lactate dehydrogenase and creatine phosphokinase. In addition, cardiotoxicity was further confirmed by the significant increase in lipid peroxidation expressed as thiobarbituric acid reactive substances (TBARS), catalase (CAT) and superoxide dismutase (SOD). Administration of aloe vera polysaccharides for 14 days produced a marked protection against cardiotoxicity induced by DOX evidenced by significant reductions in serum lactate dehydrogenase, serum creatine phosphokinase, cardiac TBARS, CAT and SOD along with increased levels of blood and tissue GSH in a dose-dependent manner. The present investigation is the first to establish the antioxidant potency of the polysaccharides from aloe vera against DOX-induced myocardial OS.

  13. Gamma irradiation improves the antioxidant activity of Aloe vera (Aloe barbadensis miller) extracts

    Science.gov (United States)

    Mi Lee, Eun; Bai, Hyoung-Woo; Sik Lee, Seung; Hyun Hong, Sung; Cho, Jae-Young; Yeoup Chung, Byung

    2012-08-01

    Aloe has been widely used in food products, pharmaceuticals, and cosmetics because of its aromatic and therapeutic properties. In the present study, the ethanolic extracts of aloe gel were gamma-irradiated from 10 to 100 kGy. After gamma irradiation, the color of the ethanolic extracts of aloe gel changed to red; this color persisted up to 40 kGy but disappeared above 50 kGy. Liquid chromatography/mass spectrometry analysis demonstrated the production of a new, unknown compound (m/z=132) after gamma irradiation of the ethanolic extracts of aloe gel. The amount of this unknown compound increased with increasing irradiation up to 80 kGy, and it was degraded at 100 kGy. Interestingly, it was found that gamma irradiation significantly increased the antioxidant activity, as measured by the 1,1-diphenyl-2-picrylhydrazyl-radical scavenging capacity. The antioxidant activity of aloe extract was dramatically increased from 53.9% in the non-irradiated sample to 92.8% in the sample irradiated at 40 kGy. This strong antioxidant activity was retained even at 100 kGy. These results indicate that gamma irradiation of aloe extract can enhance its antioxidant activity through the formation of a new compound. Based on these results, increased antioxidant activity of aloe extracts by gamma rays can be applied to various industries, especially cosmetics, foodstuffs, and pharmaceuticals.

  14. Gamma irradiation improves the antioxidant activity of Aloe vera (Aloe barbadensis miller) extracts

    International Nuclear Information System (INIS)

    Aloe has been widely used in food products, pharmaceuticals, and cosmetics because of its aromatic and therapeutic properties. In the present study, the ethanolic extracts of aloe gel were gamma-irradiated from 10 to 100 kGy. After gamma irradiation, the color of the ethanolic extracts of aloe gel changed to red; this color persisted up to 40 kGy but disappeared above 50 kGy. Liquid chromatography/mass spectrometry analysis demonstrated the production of a new, unknown compound (m/z=132) after gamma irradiation of the ethanolic extracts of aloe gel. The amount of this unknown compound increased with increasing irradiation up to 80 kGy, and it was degraded at 100 kGy. Interestingly, it was found that gamma irradiation significantly increased the antioxidant activity, as measured by the 1,1-diphenyl-2-picrylhydrazyl-radical scavenging capacity. The antioxidant activity of aloe extract was dramatically increased from 53.9% in the non-irradiated sample to 92.8% in the sample irradiated at 40 kGy. This strong antioxidant activity was retained even at 100 kGy. These results indicate that gamma irradiation of aloe extract can enhance its antioxidant activity through the formation of a new compound. Based on these results, increased antioxidant activity of aloe extracts by gamma rays can be applied to various industries, especially cosmetics, foodstuffs, and pharmaceuticals.

  15. Comparative evaluation of the effect of chlorhexidine and Aloe barbadensis Miller (Aloe vera) on dentin stabilization using shear bond testing

    Science.gov (United States)

    Sinha, Dakshita Joy; Jaiswal, Natasha; Vasudeva, Agrima; Garg, Paridhi; Tyagi, Shashi Prabha; Chandra, Priyanka

    2016-01-01

    Introduction: The main objective of adhesive dentistry is to create an effective, durable union between the tooth structure and restorative material. However, degradation of adhesive dentine interface remains largely responsible for the relatively short lifetime of tooth colored resin restoration. Aim: The aim of the study is to compare the dentin collagen stabilization property of Chlorhexidine (CHX) and Aloe barbadensis Miller using shear bond strength testing. Materials and Methods: Occlusal reduction was done in sixty extracted human mandibular molars to expose the mid coronal dentin and divided into three groups n = 20. Following the surface pretreatment (Group 1 = control, Group 2 = CHX, Group 3 = Aloevera), dentine bonding agent and composite resin were applied and cured. The specimens were then subjected to shear bond strength testing. Results: From the results analyzed, it was noted that there was statistically significant difference between the groups Control and CHX and Control and A. barbadensis Miller (P 0.05). Hence, the following result for the shear bond strengths to dentin was obtained: Control < CHX ≈ A. barbadensis Miller. Conclusion: CHX and A. barbadensis Miller, as pretreatment agents of acid demineralized dentin collagen, has no adverse effect on the immediate shear bond strength of a two-step etch and rinse adhesive to dentin. PMID:27656056

  16. Comparative evaluation of the effect of chlorhexidine and Aloe barbadensis Miller (Aloe vera) on dentin stabilization using shear bond testing

    Science.gov (United States)

    Sinha, Dakshita Joy; Jaiswal, Natasha; Vasudeva, Agrima; Garg, Paridhi; Tyagi, Shashi Prabha; Chandra, Priyanka

    2016-01-01

    Introduction: The main objective of adhesive dentistry is to create an effective, durable union between the tooth structure and restorative material. However, degradation of adhesive dentine interface remains largely responsible for the relatively short lifetime of tooth colored resin restoration. Aim: The aim of the study is to compare the dentin collagen stabilization property of Chlorhexidine (CHX) and Aloe barbadensis Miller using shear bond strength testing. Materials and Methods: Occlusal reduction was done in sixty extracted human mandibular molars to expose the mid coronal dentin and divided into three groups n = 20. Following the surface pretreatment (Group 1 = control, Group 2 = CHX, Group 3 = Aloevera), dentine bonding agent and composite resin were applied and cured. The specimens were then subjected to shear bond strength testing. Results: From the results analyzed, it was noted that there was statistically significant difference between the groups Control and CHX and Control and A. barbadensis Miller (P 0.05). Hence, the following result for the shear bond strengths to dentin was obtained: Control < CHX ≈ A. barbadensis Miller. Conclusion: CHX and A. barbadensis Miller, as pretreatment agents of acid demineralized dentin collagen, has no adverse effect on the immediate shear bond strength of a two-step etch and rinse adhesive to dentin.

  17. Clear Evidence of Carcinogenic Activity by a Whole-Leaf Extract of Aloe barbadensis Miller (Aloe vera) in F344/N Rats

    OpenAIRE

    Boudreau, Mary D.; Mellick, Paul W.; Olson, Greg R.; Felton, Robert P.; Thorn, Brett T.; Beland, Frederick A.

    2012-01-01

    Aloe barbadensis Miller (Aloe vera) is an herbal remedy promoted to treat a variety of illnesses; however, only limited data are available on the safety of this dietary supplement. Drinking water exposure of F344/N rats and B6C3F1 mice to an Aloe vera whole-leaf extract (1, 2, and 3%) for 13 weeks resulted in goblet cell hyperplasia of the large intestine in both species. Based upon this observation, 2-year drinking water studies were conducted to assess the carcinogenic potential of an Aloe ...

  18. Análise sazonal do potencial antimicrobiano e teores de flavonoides e quinonas de extratos foliares de Aloe arborescens Mill., Xanthorrhoeaceae Seasonal analysis from the antimicrobial potency and flavonoid and quinone content from Aloe arborescens Mill., Xanthorrhoeaceae, leaf extracts

    Directory of Open Access Journals (Sweden)

    Fernando Leite Cardoso

    2010-03-01

    Full Text Available Este trabalho teve como objetivos avaliar o potencial antimicrobiano e os teores de flavonoides e quinonas de extratos foliares de Aloe arborescens Mill., Xanthorrhoeaceae, produzidos em diferentes épocas do ano. Extratos etanólicos e clorofórmicos foram preparados a partir de folhas, os bioensaios de atividade antimicrobiana foram desenvolvidos pelo método de macrodiluição em caldo, e dosagens de flavonoides e quinonas foram realizadas nos extratos. Todos os extratos apresentaram ação inibitória sobre os microrganismos testados. O extrato clorofórmico de inverno apresentou a menor CIM (128 µg/mL sobre B. subtilis. Os extratos clorofórmicos de inverno, primavera e verão apresentaram maior atividade antimicrobiana em relação ao extrato clorofórmico de outono. O extrato etanólico de inverno apresentou a menor CIM (256 µg/mL e a menor CMM (512 µg/mL sobre K. pneumoniae. Os extratos etanólicos de verão e outono mostraram baixa atividade antimicrobiana. Os teores de quinonas das folhas foram maiores nos períodos mais quentes de coleta (verão e outono, enquanto os teores de flavonoides foram semelhantes nos quatro períodos de coleta.This work has the objective of evaluate the antimicrobial potency and the content of flavonoids and quinones from the Aloe arborescens Mill., Xanthorrhoeaceae, leaf extracts produced in the four seasons of the year. Ethanol and chloroform extracts were prepared from the leaves, the bioassays from antimicrobial activity were developed by the macrodilution method in broth, and dosages of flavonoids and quinones were performed in the extracts. The winter chloroform extract showed the lowest CIM (128 µg/mL on B. subtilis. The ethanol extract showed the lowest CIM (256 µg/mL and the lowest CMM (512 µg/mL on K. pneumoniae. The summer and fall ethanol extracts showed low antimicrobial activity. The quinones extracts showed inhibitory activity on the tested microorganisms. The winter, spring and summer

  19. The content of secondary phenol metabolites in pruned leaves of Aloe arborescens, a comparison between two methods: leaf exudates and leaf water extract.

    Science.gov (United States)

    Gutterman, Yitzchak; Chauser-Volfson, Elena

    2008-10-01

    Aloe arborescens plants, originating from the deserts of South Africa, are grown in the Introduction Garden at Sede Boker in the Negev Desert of Israel. In previous studies, we developed agro-technical methods to raise the content of secondary phenol metabolites (SPhMs) in the Aloe leaves. Plants that are subjected to repeated leaf pruning respond by increasing the content of their SPhMs. The SPhMs found in Aloe arborescens include barbaloin, aloenin and derivatives of aloeresin. Such compounds are used for many purposes, including human skin protection from sun and fire burns and high radiation, as products of the pharmaceutics and cosmetics industries, and as food supplements for treating stomach ulcers and diabetes. In the current study, the SPhMs were separated from pruned leaves of the same A. arborescens plants at the same time by two methods: (1) exudation by squeezing the tissues of the leaves, (2) immersion of the leaves' pruned cut bottom in water and collection of the extract. The exudates and extract were frozen, freeze-dried to a powder and the SPhMs were then separated by chromatography. The yield of powder from water extraction from pruned leaves was much lower than the yield from the exudates. However, higher percentages of the powder from the water extraction contained SPhMs (between 80 and 92.7%). The content of powder in leaf exudates from pruned leaves was much higher because the SPhMs were squeezed out from the cells and tissues. However, the percentages of SPhMs in this powder were much lower (between 39 and 62%). PMID:18470597

  20. PREPARATION OF GLIMEPIRIDE ALOE BARBADENSIS MILLER LEAVES MUCILAGE AND POVIDONE CONTROLLED RELEASE MATRIX TABLETS: IN VITRO AND IN VIVO EVALUATION

    Directory of Open Access Journals (Sweden)

    Hindustan Abdul Ahad

    2011-02-01

    Full Text Available The main purpose of the present study was to prepare Glimepiride matrix tablets with Aloe barbadensis miller leaves mucilage and Povidone and to study its novelty as a matrix forming polymer for controlled release tablet formulations. Physicochemical properties of the dried powdered Aloe barbadensis miller mucilage and Povidone blend, drug-excipient compatibility studies, pre formulation studies, post formulation studies, in vitro drug release studies, mathematical modeling of in vitro dissolution data and in vivo hypoglycemic effects in rabbits were performed. Aloe barbadensis miller mucilage was found to have good flow properties, Glimepiride was found compatible with the excipients used. The granules were found to have good flow properties and in vitro drug release pattern. The mathematical modeling proved that the release of drug from the formulations followed zero order release. The reduced hypoglycemic actions were maintained for prolonged time in in vivo hypoglycemic studies. All these values were found to be satisfactory. The data revealed that the dried Aloe barbadensis miller mucilage and Povidone combination can be used as a matrix forming polymers for making controlled release matrix tablets.

  1. Microbiological stabilization of Aloe vera (Aloe barbadensis Miller) gel by high hydrostatic pressure treatment.

    Science.gov (United States)

    Reyes, Juan E; Guanoquiza, Manuel I; Tabilo-Munizaga, Gipsy; Vega-Galvez, Antonio; Miranda, Margarita; Pérez-Won, Mario

    2012-09-01

    The effect of high hydrostatic pressure (HHP) treatment (300, 400 and 500 MPa for 1 and 3 min at 20 °C) on the microbiological shelf-life and microbiota composition of Aloe vera gel during 90 days of storage at 4 °C was investigated. Aerobic mesophilic and psychrotrophic bacteria, as well as moulds and yeasts, were enumerated after HHP treatment and through cold storage. Randomly selected isolates from the count plates were identified by standard methods and the API identification system. Results showed that HHP treatment at or over 400 MPa for 3 min were effective to keep the microbial counts to undetectable levels during the whole storage period, and consequently the microbiological shelf-life of A. vera gel was extended for more than 90 days at 4 °C. The microbiota in the untreated A. vera gel was dominated by Gram-negative bacteria (mostly Rahnella aquatilis) and yeasts (mostly Rhodotorula mucilaginosa). In contrast, Gram-positive bacteria tentatively identified as Arthrobacter spp. and Micrococcus/Kocuria spp. were the predominant microorganisms in samples pressurized at 300 MPa for 1 and 3 min, while Bacillus megaterium predominating in samples treated at 400 MPa for 1 min. At 400 MPa for 3 min and above, the microbial growth was completely suppressed during at least 90 days; however, viable spore-formers were detected by enrichment. PMID:22884172

  2. Influence of Aloe arborescens Mill. extract on selected parameters of pro-oxidant-antioxidant equilibrium and cytokine synthesis in rowers.

    Science.gov (United States)

    Basta, Piotr; Pilaczyńska-Szczęśniak, Łucja; Woitas-Ślubowska, Donata; Skarpańska-Stejnborn, Anna

    2013-08-01

    This investigation examined the effect of supplementation with Biostimine, extract from Aloe arborescens Mill. leaves, on the levels of pro-oxidant-antioxidant equilibrium markers and anti- and proinflammatory cytokines in rowers subjected to exhaustive exercise. This double-blind study included 18 members of the Polish Rowing Team. Subjects were randomly assigned to the supplemented group (n = 9), which received one ampoule of Biostimine once daily for 4 weeks, or to the placebo group (n = 9). Subjects performed a 2,000-meter-maximum test on a rowing ergometer at the beginning and end of the preparatory camp. Blood samples were obtained from the antecubital vein before each exercise test, 1 min after completing the test and after a 24-hr recovery period. Superoxide dismutase and glutathione peroxidase activity as well as the concentration of thiobarbituric acid reactive substances (TBARS) were assessed in erythrocytes. In addition, total antioxidant capacity (TAC) and creatine kinase activity were measured in plasma samples, and cytokine (IL-6, IL-10) concentrations were determined in the serum. Before and after Biostimine supplementation, exercise significantly increased the values of SOD, IL-6, IL-10, and TBARS in both groups. However, postexercise and recovery levels of TBARS were significantly lower in athletes receiving Biostimine than in controls. After supplementation, TAC was the only variable with the level being significantly higher in the supplemented group than in the placebo group. Consequently, we can conclude that Biostimine supplementation reduces the postexercise level of TBARS by increasing the antioxidant activity of plasma but has no effect on inflammatory markers. PMID:23349254

  3. Isolation of a cDNA for a phosphoenolpyruvate carboxylase from a monocot CAM-plant, Aloe arborescens: structure and its gene expression.

    Science.gov (United States)

    Honda, H; Okamoto, T; Shimada, H

    1996-09-01

    A phosphoenolpyruvate carboxylase (PEPCase) cDNA was isolated from Aloe arborescens, a monocot CAM plant. Northern analysis of the PEPCase transcript indicated that it is specifically expressed in green leaves, strongly suggesting its involvement in CAM photosynthesis. No diurnal change in expression level was evident. Western blot analysis also showed no alteration of the amount of the PEPCase protein. These results suggest that circadian rhythm in PEPCase activity may be regulated post-translationally. The representative cDNA clone contained an ORF encoding 964 amino acid residues. Deduced amino acid sequence of the aloe PEPCase is highly conserved as compared with other PEPCases. The phosphorylation site which may be modified by PEPC-kinase was conserved. An evolutional map with known PEPCases suggested that CAM-type PEPCases were located between C4 and housekeeping PEPCases. PMID:8888625

  4. [Radio protective drug production from fresh leaves of Aloe arborescens Mill].

    Science.gov (United States)

    Bakuridze, A Dzh; Nikolaev, S M; Berashvili, D T; Bakuridze, K A; Tsomaia, I V

    2009-06-01

    Nowadays, phytogenous drugs are wildly used as radio protective substances. The aim of the research was to study radio protective characteristics of aloe juice fraction and to develop new technology for radio protective drug production. Technological scheme for getting the drug in two stages. The first stage - extraction of juice from fresh leaves; the second stage - extracting bagasse have been developed and optimal environment for bagasse extraction are defined: Infusion of bagasse with 96 % ethyl spirit (1:1) during 30 minutes, continuation of extracting with water on correlation to raw materials 10:1 at temperature of 70 degrees C during 30 minutes. For the basis of the first series of balanced loading there are taken the optimal parameters of extracting process, on the basis of which in its turn was developed technological scheme of getting dry extract of aloe. Dry extract is a fine-dispersed reddish-yellow (brownish-yellow) powder, which can be easily dissolved in warm (40-60 degrees C) water. Pharmacological researches were conducted in the Institute of General and Experimental Biology, Siberian Branch, Russian. Academy of Sciences. The remarkable radio protective effect of the drug was revealed. PMID:19578223

  5. The distribution of the phenolic metabolites barbaloin, aloeresin and aloenin as a peripheral defense strategy in the succulent leaf parts of Aloe arborescens.

    Science.gov (United States)

    Gutterman; Chauser-Volfson

    2000-11-01

    Aloe arborescens is a large, multi-stemmed shrub. It is used as hedge plants to protect agricultural fields or stock and as horticultural plants in gardens. In natural habitats it is one of the very common Aloe species along the Indian Ocean coast of southern Africa, from the Cape, in the south, to Zimbabwe and Malawi in the north. Secondary phenolic metabolites such as barbaloin (Rf 0.31-0.35), aloeresin (Rf 0.25-0.3) and aloenin (Rf 0.51-0.55) have been found to be distributed in the succulent leaves of Aloe arborescens in a peripheral defense strategy. The youngest leaves have the highest content. The terminal third of each leaf has the highest content and the basal third, the lowest. Along the leaf margins, on the top third and adaxial side, the content is the highest and in the base third, the lowest along the leaf center on the abaxial side. Similar relative amounts of these three secondary phenolic metabolites were found in the different leaf locations. The leaf orientation may affect the total content of these three phenols but not their relative amounts in the different parts of the leaves. It is possible that the more often the plant parts are damaged by consumption by animals such as elephants, kudu or insects, the greater the increase of their phenolic metabolites. This increase may reduce or prevent further consumption when the content of the metabolites reaches a certain level. The plants then have a chance to renew themselves. PMID:10913844

  6. Effect of leaf extracts of Aloe arborescens Mill subsp. natalensis Berger on growth of Trichophyton mentagrophytes.

    Science.gov (United States)

    Fujita, K; Yamada, Y; Azuma, K; Hirozawa, S

    1978-07-01

    The antifungal activity of a lyophilized powder containing aloe leaf homogenate (whole-leaf powder) against Trichophyton mentagrophytes was investigated. The minimal inhibitory concentration was 25 mg/ml by the agar dilution method, using Sabouraud glucose agar medium. At subinhibitory concentrations, the powder exerted its main effect on colony growth by prolongation of the lag phase and inhibition of growth rate. Homogenates of fresh whole leaf were filtered through Whatman GF/A paper, and the filtrate was dialyzed and concentrated by molecular filtration using an Amicon hollow-fiber dialyzer concentrator DC-2, and a powder containing components with molecular weights higher than 10,000 (high-molecular-weight component powder) was prepared by lyophilization. The minimal inhibitory concentrations against three strains of T. mentagrophytes were all 10 mg/ml. The inhibitory activity was fungicidal and was lost by heating at 100 degrees C for 30 min. Both the whole-leaf powder and the high-molecular-weight component powder induced various morphological abnormalities in spores and hyphae by the inhibition of spore germination and development of hyphae. PMID:686703

  7. Crassulacean acid metabolism (CAM) in leaves of Aloe arborescens mill : Comparative studies of the carbon metabolism of chlorenchym and central hydrenchym.

    Science.gov (United States)

    Kluge, M; Knapp, I; Kramer, D; Schwerdtner, I; Ritter, H

    1979-01-01

    In the succulent leaves of Aloe arborescens Mill diurnal oscillations of the malic acid content, being indicative of Crassulacean Acid Metabolism (CAM), were exhibited only by the green mesophyll. In contrast, the malic acid level of the central chloroplast-free water-storing tissue remained constant throughout the day-night cycle. Apart from malate, the green tissue contained high amounts of isocitrat which was lacking in the water tissue. There was no significant transfer from the green mesophyll to the water tissue of (14)C fixed originally via dark (14)CO2 fixation in the mesophyll. Both isolated mesophyll and water tissue were capable of dark CO2 fixation yielding mainly malate as the first stable product. Both tissues have phosphoenolpyruvate carboxylase. However, the enzymes derived from the both sources could be distinguished by their molecular weights and by their kinetic properties, suggesting different phosphoenolpyruvate carboxylase proteins. The conclusion drawn from the experiments is that in a. arborescens the CAM cycle proceeds exclusively in the green mesophyll and that the water tissue, though capable of malate synthesis via β-carboxylation of phosphoenolpyruvate, behaves as an independent metabolic system where CAM is lacking. This view is supported by the finding that the cell walls bordering the green mesophyll from the water tissue lack plasmodesmata, hence conveniant pathways of metabolite transport. PMID:24317763

  8. Very-long-chain 3-hydroxy fatty acids, 3-hydroxy fatty acid methyl esters and 2-alkanols from cuticular waxes of Aloe arborescens leaves.

    Science.gov (United States)

    Racovita, Radu C; Peng, Chen; Awakawa, Takayoshi; Abe, Ikuro; Jetter, Reinhard

    2015-05-01

    The present work aimed at a comprehensive chemical characterization of the cuticular wax mixtures covering leaves of the monocot species Aloe arborescens. The wax mixtures were found to contain typical aliphatic compound classes in characteristic chain length distributions, including alkanes (predominantly C31), primary alcohols (predominantly C28), aldehydes (predominantly C32), fatty acid methyl esters (predominantly C28) and fatty acids (bimodal distribution around C32 and C28). Alkyl esters ranging from C42 to C52 were identified, and found to mainly contain C28 alcohol linked to C16-C20 acids. Three other homologous series were identified as 3-hydroxy fatty acids (predominantly C28), their methyl esters (predominantly C28), and 2-alkanols (predominantly C31). Based on structural similarities and homolog distributions, the biosynthetic pathways leading to these novel wax constituents can be hypothesized. Further detailed analyses showed that the A. arborescens leaf was covered with 15 μg/cm(2) wax on its adaxial side and 36 μg/cm(2) on the abaxial side, with 3:2 and 1:1 ratios between epicuticular and intracuticular wax layers on each side, respectively. Terpenoids were found mainly in the intracuticular waxes, whereas very-long-chain alkanes and fatty acids accumulated to relatively high concentrations in the epicuticular wax, hence near the true surface of the leaf. PMID:25200334

  9. Revisión de la aloe vera (Barbadensis Miller) en la dermatología actual Revision Of Aloe Vera (Barbadensis Miller) In Actual Dermatology

    OpenAIRE

    GM Ferraro

    2009-01-01

    El Aloe vera es una planta de uso popular en el tratamiento de algunas enfermedades de la piel y de aplicación frecuente en la cosmetología. Forma parte de diversas cremas o geles, siendo usado como antiinflamatorio y reconstituyente del tejido epitelial. Aunque se conocen varios mecanismos de acción e indicaciones clínicas, se debe realizar una revisión de las mismas para su uso, avalados por ensayos controlados para determinar su eficacia real.The Aloe vera is a popular plant used in the tr...

  10. Clear evidence of carcinogenic activity by a whole-leaf extract of Aloe barbadensis miller (aloe vera) in F344/N rats.

    Science.gov (United States)

    Boudreau, Mary D; Mellick, Paul W; Olson, Greg R; Felton, Robert P; Thorn, Brett T; Beland, Frederick A

    2013-01-01

    Aloe barbadensis Miller (Aloe vera) is an herbal remedy promoted to treat a variety of illnesses; however, only limited data are available on the safety of this dietary supplement. Drinking water exposure of F344/N rats and B6C3F1 mice to an Aloe vera whole-leaf extract (1, 2, and 3%) for 13 weeks resulted in goblet cell hyperplasia of the large intestine in both species. Based upon this observation, 2-year drinking water studies were conducted to assess the carcinogenic potential of an Aloe vera whole-leaf extract when administered to F344/N rats (48 per sex per group) at 0.5, 1, and 1.5%, and B6C3F1 mice (48 per sex per group) at 1, 2, and 3%. Compared with controls, survival was decreased in the 1.5% dose group of female rats. Treatment-related neoplasms and nonneoplastic lesions in both species were confined primarily to the large intestine. Incidences of adenomas and/or carcinomas of the ileo-cecal and cecal-colic junction, cecum, and ascending and transverse colon were significantly higher than controls in male and female rats in the 1 and 1.5% dose groups. There were no neoplasms of the large intestine in mice or in the 0 or 0.5% dose groups of rats. Increased incidences of mucosa hyperplasia of the large intestine were observed in F344/N rats, and increased incidences of goblet cell hyperplasia of the large intestine occurred in B6C3F1 mice. These results indicate that Aloe vera whole-leaf extract is an intestinal irritant in F344/N rats and B6C3F1 mice and a carcinogen of the large intestine in F344/N rats.

  11. Optical properties of rhodoxanthin accumulated in Aloe arborescens Mill. leaves under high-light stress with special reference to its photoprotective function.

    Science.gov (United States)

    Merzlyak, Mark; Solovchenko, Alexei; Pogosyan, Sergei

    2005-04-01

    In Aloe arborescens Mill. leaves, strong sunlight or its combination with drought induces the accumulation of the red keto-carotenoid, rhodoxanthin. Simultaneously, the transformation of chloroplasts into chromoplasts accompanied by degradation of thylakoid membranes and formation of plastoglobuli, large in size and number, takes place. Depending on stress conditions the build up of rhodoxantin occurred along with the loss of chlorophyll or on the background of relatively high content of the pigment in the leaves. Microspectrophotometrical measurements showed the presence of chlorophyll-free plastids and retention of carotenoids during leaf adaptation to strong sunlight. The plastid spectra contained absorption bands of common for higher plants carotenoids together with those of rhodoxantin, with absorption maxima situated in the blue (440-480 nm) and the green ranges of the spectrum, respectively. The studies of whole-leaf optical properties revealed a broad band of rhodoxanthin absorption in the blue-green range peaking near 540-550 nm. Within this spectral band the accumulation of rhodoxanthin occurring, probably, in plastoglobuli considerably increased light absorption by stressed Aloe leaves. A possible photoprotective function of rhodoxanthin and other carotenoids as an internal light trap analogous to that accomplished by anthocyanins in other plant species is discussed. PMID:15803203

  12. Comparative evaluation of the effect of chlorhexidine and Aloe barbadensis Miller (Aloe vera on dentin stabilization using shear bond testing

    Directory of Open Access Journals (Sweden)

    Dakshita Joy Sinha

    2016-01-01

    Conclusion: CHX and A. barbadensis Miller, as pretreatment agents of acid demineralized dentin collagen, has no adverse effect on the immediate shear bond strength of a two-step etch and rinse adhesive to dentin.

  13. Mass spectrometry-based metabolite profiling and antioxidant activity of Aloe vera ( Aloe barbadensis Miller) in different growth stages.

    Science.gov (United States)

    Lee, Sarah; Do, Seon-Gil; Kim, Sun Yeou; Kim, Jinwan; Jin, Yoojeong; Lee, Choong Hwan

    2012-11-14

    Metabolite profiling of four different-sized Aloe vera plants was performed using gas chromatography-ion trap-mass spectrometry (GC-IT-MS) and ultra performance liquid chromatography-quadrupole-time of flight-mass spectrometry (UPLC-Q-TOF-MS) with multivariate analysis. Amino acids, sugars, and organic acids related to growth and development were identified by sizes. In particular, the relative contents of glucose, fructose, alanine, valine, and aspartic acid increased gradually as the size of the aloe increased. Anthraquinone derivatives such as 7-hydroxy-8-O-methylaloin, 7-hydroxyaloin A, and 6'-malonylnataloins A and B increased gradually, whereas chromone derivatives decreased continuously as the size of the aloe increased. The A30 aloe (size = 20-30 cm) with relatively high contents of aloins A and B, was suggested to have antioxidant components showing the highest antioxidant activity among the four different sizes of aloe. These data suggested that MS-based metabolomic approaches can illuminate metabolite changes associated with growth and development and can explain their change of antioxidant activity. PMID:23050594

  14. Revisión de la aloe vera (Barbadensis Miller en la dermatología actual Revision Of Aloe Vera (Barbadensis Miller In Actual Dermatology

    Directory of Open Access Journals (Sweden)

    GM Ferraro

    2009-12-01

    Full Text Available El Aloe vera es una planta de uso popular en el tratamiento de algunas enfermedades de la piel y de aplicación frecuente en la cosmetología. Forma parte de diversas cremas o geles, siendo usado como antiinflamatorio y reconstituyente del tejido epitelial. Aunque se conocen varios mecanismos de acción e indicaciones clínicas, se debe realizar una revisión de las mismas para su uso, avalados por ensayos controlados para determinar su eficacia real.The Aloe vera is a popular plant used in the treatment of certain skin diseases that has a frequent application in cosmetology. It forms a part of diverse creams or gels, being used as anti-inflammatory and restorative of epithelial tissue. Although there are several mechanisms of action and clinical indications, a review of its use should be done supported by controlled trials to determine its effectiveness.

  15. Tissue Culture and Rapid Propagation with Low Costs of Aloe Arborescens Mill and Aloe Mitriformis Mill%木立芦荟和三角芦荟的组织培养和低成本快繁

    Institute of Scientific and Technical Information of China (English)

    那宁馨; 郭晓华; 齐淑艳; 昌恩梓; 商显礼

    2001-01-01

    以MS+BA3+NAA0.2和MS+BA4+NAA0.2分别为木立芦荟(Aloe arborescens Mill)和三角芦荟(Aloe mitriformis Mill)的诱导培养基.1/2MS+BA2+NAA0.2和MS+BA3+NAA0.2分别为两种芦荟的增殖培养基,对茎段、茎尖和吸芽进行离体培养.以4周为一个继代周期,每周期可增殖6~8倍,现已经过26个继代周期,一个外植体每年可增殖至813个芽苗.为减轻褐化,降低温度至22℃、光照强度800lx,附加活性炭3~5g@L-1.用白糖替代蔗糖,自来水替代蒸馏水,果酱瓶替代三角瓶,既不影响培养效果又可降低生产成本.

  16. An isozyme of the NADP-malic enzyme of a CAM plant, Aloe arborescens, with variation on conservative amino acid residues.

    Science.gov (United States)

    Honda, H; Akagi, H; Shimada, H

    2000-02-01

    In Aloe arborescens, an obligate CAM plant, Western analysis detected three major isoforms of NADP-malic enzyme (NADP-ME), 72kDa with a pI of 6.0, 65kDa with a pI of 5.6 and 65kDa with a pI of 5.5. Among them, the 65kDa protein with a pI of 5.5 was leaf-specific, and the 65kDa protein with a pI of 5.6 was found only in roots, whereas the 72kDa protein was uniformly detected in both organs. Activity staining indicated enzyme activity of both 65kDa NADP-MEs but little activity of the 72kDa protein. A cDNA clone encoding a leaf-abundant NADP-ME, AME1, was isolated. Deduced amino acid sequence of AME1 showed a high degree of homology to known NADP-MEs, but it was also found that AME1 contained substitutions on five conservative amino acid residues, some of which have been predicted to be important for their enzyme activity. Transgenic rice carrying the aloe AME1 gene efficiently produced an additional 65kDa protein with a pI of 5.5 as an active NADP-ME. These results indicate that AME1 corresponds to the leaf-specific 65kDa NADP-ME, which may be involved in CAM photosynthesis. It was also shown that substitutions of these conservative amino acid residues identified in AME1 still allowed it to give enzyme activity. PMID:10675616

  17. Developmental and anatomical studies on the leaves of Aloe arborescens%木立芦荟叶的发育解剖学研究

    Institute of Scientific and Technical Information of China (English)

    李景原; 沈宗根; 胡正海

    2001-01-01

    应用植物解剖学方法研究了木立芦荟(Aloe arborescens Mill.)叶的发育过程.研究结果表明,叶原基在发育早期其形态是不对称的,内部为同形细胞组成,但很快分化成原表皮,原形成层束和基本分生组织.以后,原表皮发育成表皮,位于原表皮下的2~5层基本分生组织细胞发育成同化薄壁组织,而位于中央的基本分生组织细胞则发育成储水薄壁组织,原形成层束发育成维管束.维管束由维管束鞘、木质部、韧皮部和大型薄壁细胞组成.大型薄壁细胞起源于原形成层束,位于韧皮部内,其发育迟于筛管、伴胞,为芦荟属植物叶的结构特征.

  18. Callus Induction and Rapid Propagation of Aloe arborescens var. natalensis%木立芦荟愈伤组织的诱导及快速繁殖

    Institute of Scientific and Technical Information of China (English)

    傅术琳; 徐重益; 程智慧

    2002-01-01

    @@ 1 植物名称木立芦荟(Aloe arborescens var. natalensis). 2 材料类别幼嫩茎段、茎尖、叶片、根. 3 培养条件愈伤组织诱导培养基:(1)MS+2,4-D 2.0 mg*L-1(单位下同);(2)MS+NAA 2.0;(3)MS+6-BA 0.5+2,4-D 0.5+0.2%葡萄糖+CH 400+ABA 0.5.愈伤组织增殖培养基:(4)MS+2,4-D 1.0; (5)MS+NAA 1.0.不定芽诱导培养基:(6)MS+6-BA 3.0.芽增殖培养基:(7)MS+6-BA 2.0.壮苗生根培养基:(8)MS+NAA 0.5.以上培养基均加有0.7%琼脂和3%蔗糖,pH 调为5.8.培养温度(25±1)℃,光照15 h*d-1,光照度1 500 lx.

  19. Active constituents from Aloe arborescens as BACE inhibitors%木立芦荟中BACE抑制活性成分的研究

    Institute of Scientific and Technical Information of China (English)

    高博; 姚春所; 周金云; 陈若芸; 方唯硕

    2006-01-01

    目的 从木立芦荟(Aloe arborescens)中寻找新的BACE(β-分泌酶)抑制活性成分.方法 用硅胶正相色谱及反相色谱技术进行活性成分的分离纯化,根据理化性质、光谱资料进行结构鉴定.结果 从木立芦荟95%乙醇提取物的乙酸乙酯部分和正丁醇部分,分离得到了8个化合物:异丁酰基芦荟宁A(1),芦荟宁A(2),芦荟大黄索(3),(E)-2-acetonyl-8-(2'-O-feruloxyl)-β-D-glucopyranosyl-7-methoxy-5-methyl-chromone(4),7-O-methyl aloeresin A(5),芦荟苷A(6),elgonica-dimer A(7)和elgonica-dimer B(8).结论 化合物1为新化合物,化合物4为首次从该植物中分离得到.活性测试结果表明,化合物2,4,5,6对BACE有一定的抑制活性.

  20. Development of Vascular Bundles in Aloe arborescens Leaves%木立芦荟叶内维管束发育过程的研究

    Institute of Scientific and Technical Information of China (English)

    廖海民; 沈宗根; 胡正海

    2005-01-01

    采用半薄切片和组织化学方法研究了木立芦荟(Aloe arborescens)叶内维管束的发育过程,并着重于维管束鞘细胞和芦荟素细胞的来源及组织类型.结果表明:维管束由原形成层发育而来,但在分化原生韧皮部筛管时,其外侧仍保留一层原形成层细胞,以后分裂、增大成为特殊的大型薄壁细胞(芦荟素细胞),芦荟素细胞应属于韧皮部的一部分.而维管束鞘细胞则来源于基本分生组织,属于基本组织的范畴,与维管束不同源.

  1. Chemical and physical properties of aloe vera (Aloe barbadensis Miller) gel stored after high hydrostatic pressure processing

    OpenAIRE

    Karina Di Scala; Antonio Vega-Gálvez; Kong Ah-Hen; Yissleen Nuñez-Mancilla; Gipsy Tabilo-Munizaga; Mario Pérez-Won; Claudia Giovagnoli

    2013-01-01

    The aim of this study was to evaluate the influence of high hydrostatic pressure (150, 250, 350, 450, and 550 MPa), applied for 5 minutes, on antioxidant capacity, total phenolic content, color, firmness, rehydration ratio, and water holding capacity of aloe vera gel stored for 60 days at 4 °C. The analyzed properties of the pressurized gel showed significant changes after the storage period. The highest value of total phenolic content was found at 550 MPa. However, a decrease in the antioxid...

  2. Chemical and physical properties of aloe vera (Aloe barbadensis Miller gel stored after high hydrostatic pressure processing

    Directory of Open Access Journals (Sweden)

    Karina Di Scala

    2013-03-01

    Full Text Available The aim of this study was to evaluate the influence of high hydrostatic pressure (150, 250, 350, 450, and 550 MPa, applied for 5 minutes, on antioxidant capacity, total phenolic content, color, firmness, rehydration ratio, and water holding capacity of aloe vera gel stored for 60 days at 4 °C. The analyzed properties of the pressurized gel showed significant changes after the storage period. The highest value of total phenolic content was found at 550 MPa. However, a decrease in the antioxidant capacity was observed for all pressurized gel samples when compared to the control sample (p < 0.05. The smallest changes in product color were observed at pressure levels between 150 and 250 MP. The application of high hydrostatic pressure resulted in lower gel firmness, and the lowest value was found at 150 MPa (p < 0.05. On the other hand, the untreated sample showed a greater decrease in firmness, indicating that high pressure processing preserves this property. The application of high hydrostatic pressure exhibited modifications in the food matrix, which were evaluated in terms of rehydration ratio and water holding capacity.

  3. Effect of high hydrostatic pressure on functional properties and quality characteristics of Aloe vera gel (Aloe barbadensis Miller).

    Science.gov (United States)

    Vega-Gálvez, Antonio; Miranda, Margarita; Aranda, Mario; Henriquez, Karem; Vergara, Judith; Tabilo-Munizaga, Gipsy; Pérez-Won, Mario

    2011-12-01

    The aim of this study was to evaluate the effects of high hydrostatic pressure treatment at three pressure levels (300, 400 and 500Mpa) on the functional and quality characteristics of Aloe vera gel including vitamin C and E, aloin, minerals, phenolic content and antioxidant activity. The results show that HHP exerted a clear influence on minerals content, vitamin C and E content, antioxidant activity, total phenolic and aloin content. After 35days of storage all treated samples presented a decrease in mineral content, except for phosphorus. Total phenolic content and vitamin C and E content decreased at high pressures (500MPa), while all pressurised samples showed a higher antioxidant activity and aloin content than untreated sample after 35days of storage. The maximum values of antioxidant activity and aloin were 6.55±1.26μg/ml at 300MPa and 24.23±2.27mg/100g d.m. at 400MPa. PMID:25212337

  4. Influence of high hydrostatic pressure on quality parameters and structural properties of aloe vera gel (Aloe barbadensis Miller).

    Science.gov (United States)

    Vega-Gálvez, Antonio; Miranda, Margarita; Nuñez-Mancilla, Yissleen; Garcia-Segovia, Purificación; Ah-Hen, Kong; Tabilo-Munizaga, Gipsy; Pérez-Won, Mario

    2014-10-01

    The aim of this work was to study the effect of high hydrostatic pressure (HHP) on colour, dietary fibre, vitamin C content, polysaccharides content, physico-chemical and structural properties of aloe vera gel at three pressure levels (300, 400 and 500 MPa for 3 min) after 35 days of storage at 4 ± 1 °C. The results showed that HHP exerted a clear influence on most of the quality parameters studied. Moisture, protein and fat contents did not show changes with an increasing pressure. Ash, crude fibre and carbohydrates content increased with increasing pressure. Vitamin C content did not show significant differences after 35 days of storage. The variation of colour in the samples increased at 500 MPa. Total dietary fibre, water holding capacity and firmness increased with pressure. However, all HHP-treated samples presented a decrease in hydration ratio and polysaccharides content; and also minor alterations in the structural properties were produced at HHP of 300-500 MPa, resulting in a high quality gel. PMID:25328187

  5. Identification of five phytosterols from Aloe vera gel as anti-diabetic compounds.

    Science.gov (United States)

    Tanaka, Miyuki; Misawa, Eriko; Ito, Yousuke; Habara, Noriko; Nomaguchi, Kouji; Yamada, Muneo; Toida, Tomohiro; Hayasawa, Hirotoshi; Takase, Mitunori; Inagaki, Masanori; Higuchi, Ryuuichi

    2006-07-01

    The genus Aloe in the family Liliaceae is a group of plants including Aloe vera (Aloe barbadensis MILLER) and Aloe arborescens (Aloe arborescens MILLER var. natalensis BERGER) that are empirically known to have various medical efficacies. In the present study, we evaluated the anti-hyperglycemic effect of Aloe vera gel and isolated a number of compounds from the gel. On the basis of spectroscopic data, these compounds were identified as lophenol, 24-methyl-lophenol, 24-ethyl-lophenol, cycloartanol, and 24-methylene-cycloartanol. These five phytosterols were evaluated for their anti-hyperglycemic effects in type 2 diabetic BKS.Cg-m(+/+)Lepr(db/J) (db/db) mice. In comparison with the hemoglobin A1c (HbA1c) levels of vehicle-treated mice, statistically significant decreases of 15 to 18% in HbA1c levels were observed in mice treated with 1 mug of the five phytosterols. Considering the ability to reduce blood glucose in vivo, there were no differences between the five phytosterols. Administration of beta-sitosterol did not reduce the blood glucose levels in db/db mice. After administration of the five phytosterols for 28 d, fasting blood glucose levels decreased to approximately 64%, 28%, 47%, 51%, and 55% of control levels, respectively. Severe diabetic mice treated with phytosterols derived from Aloe vera gel did not suffer weight reduction due to glucose loss in the urine. These findings suggest that Aloe vera gel and phytosterols derived from Aloe vera gel have a long-term blood glucose level control effect and would be useful for the treatment of type 2 diabetes mellitus. PMID:16819181

  6. Aloe barbadensis Miller mediated green synthesis of mono-disperse copper oxide nanoparticles: Optical properties

    Science.gov (United States)

    Gunalan, Sangeetha; Sivaraj, Rajeshwari; Venckatesh, Rajendran

    2012-11-01

    In this paper, we report on the synthesis of nanostructured copper oxide particles by both chemical and biological method. A facile and efficient synthesis of copper oxide nanoparticles was carried out with controlled surface properties via green chemistry approach. The CuO nanoparticles synthesized are monodisperse and versatile and were characterized with the help of UV-Vis, PL, FT-IR, XRD, SEM, and TEM techniques. The particles are crystalline in nature and average sizes were between 15 and 30 nm. The morphology of the nanoparticles can be controlled by tuning the amount of Aloe vera extract. This new eco-friendly approach of synthesis is a novel, cheap, and convenient technique suitable for large scale commercial production and health related applications of CuO nanoparticles.

  7. Cálculo de la resistencia a la penetración en hojas de aloe vera (Barbadenses Miller

    Directory of Open Access Journals (Sweden)

    Giovanni Torres Charry

    2013-12-01

    Full Text Available Para caracterizar la resistencia a la penetración de hojas de aloe vera, variedad Barbadenses Miller, se diseñó una máquina y se establecieron los protocolos de medición para desplazamiento y fuerza necesarios para medir la resistencia a la penetración en tres puntos diferentes de las hojas. Los resultados mostraron que no existe una relación lineal entre el desplazamiento del indentador en la hoja y la fuerza de penetración. Por otro lado, se encontró que no existen diferencias en los valores de la fuerza de penetración al evaluar ésta en distintos puntos para una misma hoja. Se hallaron diferencias en los valores obtenidos entre hojas diferentes, lo que permite suponer que existe influencia de las características dimensionales de las hojas en el valor de la fuerza de penetración. Los valores máximos obtenidos para la fuerza de penetración variaron entre 22 y 27 N, para una velocidad de avance de la herramienta de 2.6 mm/s.

  8. Comparative study on the content of polysaccharide in Aloe barbadensis Miller and Aloe ;vera L. Var. Chinensis (Haw.) Berger%库拉索芦荟与斑纹芦荟的多糖含量比较研究

    Institute of Scientific and Technical Information of China (English)

    唐建红; 刘川玉; 何洁

    2016-01-01

    Objective To determine the content of polysaccharide in Aloe barbadensis Miller and Aloe vera L. Var. Chinensis(Haw.)Berger. Methods Carubinose was used as reference substance, measured and compared polysaccharide content with the method of UV spectrophotometry at 610 nm absorbance of growth years for 1, 2, 3, 4 and 5 years of Aloe barbadensis Miller and Aloe vera L. Var. Chinensis(Haw.)Berger. Results The mannose and the absorbance was linear (r=0.998 5) in the range of 0.05 - 0.60 g/L, and the content of Aloe barbadensis Miller polysaccharide in the measured growth period was respectively 1.201, 1.485, 1.665, 2.355 and 5.040 mg/g. The content of polysaccharide in Aloe vera L. Var. Chinensis(Haw.)Berger was 0.780, 0.900, 1.035, 1.650 and 2.355 mg/g. Conclusions The content of polysaccharide in Aloe barbadensis Miller and Aloe vera L. Var. Chinensis(Haw.)Berger differed in growth years, which increased with aging and polysaccharide content in the same age of Aloe barbadensis Miller was significantly higher than that of the Aloe vera L. Var. Chinensis(Haw.)Berger.%目的:测定不同年限的库拉索芦荟与斑纹芦荟的多糖含量。方法以D-甘露糖为对照品,采用紫外分光光度法,测定生长年限为1、2、3、4及5年的库拉索芦荟和斑纹芦荟的多糖含量,并对其进行比较分析。结果甘露糖在0.05~0.60 g/L范围内与吸光度呈良好的线性关系(r=0.9985),测得生长年限为1、2、3、4及5年的库拉索芦荟多糖含量分别为1.201、1.485、1.665、2.355、5.040 mg/g;斑纹芦荟的多糖含量分别为0.780、0.900、1.035、1.650、2.355 mg/g。结论不同生长年限的库拉索芦荟和斑纹芦荟的多糖含量有差别,其含量随年限增长而增加,相同年限库拉索芦荟的多糖含量明显高于斑纹芦荟。

  9. Tissue Culture and Rapid Propagation of Aloe arborescens var. natalensis%木立芦荟的组织培养及快速繁殖

    Institute of Scientific and Technical Information of China (English)

    于萍; 王燕

    2001-01-01

    @@l 植物名称 木立芦荟(Aloe arborescens var.na-talensis)。2 材料类别 具芽点的茎段。3 培养条件 芽诱导培养基:(1)MS+6-BA 2mg·L-1(单位下同)+NAA 0.2。不定芽增殖培养基:(2)MS+6-BA 1+NAA 0.1;(3)MS+6-BA 2+NAA0.2;(4)MS+6-BA 3+NAA 0.2;(5)MS+6-BA 5+NAA 0.1。生根培养基:(6)MS+NAA 0.5;(7)1/2MS+NAA 0.5;(8)MS。以上培养基均加0.7%琼脂、3%蔗糖,pH 5.8。培养温度22~27℃,光照10~12 h·d~,光照度1 500 lx。4 生长与分化情况4.1 不定芽诱导 选取一、二年生幼芽,用自来水冲洗,剪去3/5叶片,在0.1%HgCl2溶液中灭菌8min;用无菌水冲洗3次,放在无菌滤纸上吸干水分;将叶片一层层剥掉,露出芽点;轻切茎段两端(不要切到芽点处);接种到不定芽诱导培养基(1)中。15 d左右芽点开始萌动并生长,35 d左右茎段芽点诱导成0.2~1.0 cm丛芽数个。

  10. 木立芦荟挥发油成分GC-MS分析%Study on Chemical Components of Essential Oil in Aloe arborescens Mill.by GC-MS

    Institute of Scientific and Technical Information of China (English)

    柏金辰; 杨晓虹; 高丽娜; 刘安; 王文娜; 孙薇

    2012-01-01

    用气相色谱-质谱法对木立芦荟的挥发油进行化学成分分析.采用水蒸气蒸馏法从木立芦荟中提取挥发油,用归一化法测定其百分含量,并用气相色谱-质谱法对化学成分进行鉴定.共鉴定了19种成分,占挥发油总量的63.66%以上.本方法稳定可靠、重现性好,适用于中药挥发油的化学成分分析.%The chemical components of the essential oil from A loe arborescens Mill. Were analyzed by GC-MS. Method. The essential oil was extracted from Aloe arborescens Mill. By steam distillation method, and the amount of the components from the essential oil were determined by normalization method. The components were identified by GC-MS. 19 components which were 63.66% of the total essential oil, were separated and identified. The method is reliable, stable and good repeatability. So this method can be applied to the analysis of chemical components in the essential oil from the traditional chinese medicine.

  11. 响应面优化木立芦荟皮多糖的研究%Optimization for Extraction of Polysaccharide from Skin of Aloe arborescens Mill. Using Response Surface Method

    Institute of Scientific and Technical Information of China (English)

    谌素华; 邓敏; 王维民; 李国伟; 钟赛意; 胡武

    2015-01-01

    采用响应面分析法对木立芦荟皮多糖的提取工艺进行优化,对提取率影响因素进行单因素分析后,以Box-Behnken设计评价微波时间、提取液pH和液料比3个因素显著性和交互作用,最终得出木立芦荟皮多糖的最佳提取条件为:微波时间为168 s,提取液的pH为9,液料比为52:1(mL/g),微波功率为320 W,在此条件下提取率为14.37%;并对提取的粗多糖进行红外光谱分析,结果表明木立芦荟皮粗多糖具有多糖的特征吸收峰.%The extraction technology of polysaccharide from skin slag of Aloe arborescens Mill. was studied using response Surface Method (RSM),and microwave time, Extraction liquid pH, liquid-solid ratio were selected as experimental the factors. Based on the analysis of significance and interaction among different factors, the optimal condition of extraction technology was obtained as followed:microwave time was 168 s, Extraction liquid pH was 9, liquid-solid ratio was 52 : 1 (mL/g), microwave power was 320 W. Under the conditions of extraction, the average value of three times actual measured extraction rate was 14.37%. Using IR to analyze structure of polysaccharide from skin slag of Aloe arborescens Mill, IR spectra suggested its had polysaccharide′s characteristic groups.

  12. Determination of the polysaccharides contents in three aloe of Fujian province%闽产三种芦荟叶汁中多糖含量测定

    Institute of Scientific and Technical Information of China (English)

    包国荣; 陈建斌; 陈玉枝

    2001-01-01

    本文采用硫酸-酚比色法,于490nm波长测定斑芦荟(AIoe vera L.Var.chinensis (Haw)Berg)、库拉索芦荟(Aloe barbadensis miller)、以及木立芦荟(Aloe arborescens mill)叶汁中的多糖含量,结果表明:库拉索芦荟中的多糖含量较高,斑纹芦荟次之,木立芦荟最低.

  13. 木立芦荟茎段离体培养再生植株的研究%In Vitro Plant Regeneration from Stems of Aloe arborescens var.natalensis

    Institute of Scientific and Technical Information of China (English)

    蔡小东; 张金晶

    2011-01-01

    以木立芦荟(Aloe arborescens vat.natalensis)幼嫩茎段为外植体,进行了不定芽诱导及生根的研究.结果表明,以0.1/100mL升汞处理外植体10min的灭菌效果最佳;MS+0.1 mg/L NAA+4.0 mg/L 6-BA的激素组合的出芽率为36%;筛选出木立芦荟最佳生根培养基为MS+0.2 mg/L NAA+4.5 mg/L 6-BA.%The young stems of Aloe arborescent var. Natalensis were cultured as explants to study the induction of cluster shoots and roots. It was proved appropriate that the young stems treated by 0.1 g/100mL HgCl2 for 10 min. MS+0.1 mg/L NAA+4.0 mg/L 6-BA was suitable for cluster shoots induction and multifunction as the rate of shoot induction reached 36%. The optimal root-induction media was MS+0.2 mg/L NAA+4.5 mg/L 6-BA.

  14. Study of Antoxides between Aloe Barbadensis Miller L and Aloe Arborescens Miller L%库拉索芦荟与木立芦荟抗氧化物质的比较

    Institute of Scientific and Technical Information of China (English)

    华春

    2004-01-01

    对库拉索芦荟与木立芦荟叶片组织中超氧化物歧化酶、过氧化物酶、丙二醛、维生素C及可溶性蛋白等理化指标进行了比较研究.结果表明,库拉索芦荟与木立芦荟均具有较强的抗氧化能力.

  15. Optimality in Microwave-Assisted Drying of Aloe Vera (Aloe barbadensis Miller) Gel using Response Surface Methodology and Artificial Neural Network Modeling

    Science.gov (United States)

    Das, Chandan; Das, Arijit; Kumar Golder, Animes

    2016-07-01

    The present work illustrates the Microwave-Assisted Drying (MWAD) characteristic of aloe vera gel combined with process optimization and artificial neural network modeling. The influence of microwave power (160-480 W), gel quantity (4-8 g) and drying time (1-9 min) on the moisture ratio was investigated. The drying of aloe gel exhibited typical diffusion-controlled characteristics with a predominant interaction between input power and drying time. Falling rate period was observed for the entire MWAD of aloe gel. Face-centered Central Composite Design (FCCD) developed a regression model to evaluate their effects on moisture ratio. The optimal MWAD conditions were established as microwave power of 227.9 W, sample amount of 4.47 g and 5.78 min drying time corresponding to the moisture ratio of 0.15. A computer-stimulated Artificial Neural Network (ANN) model was generated for mapping between process variables and the desired response. `Levenberg-Marquardt Back Propagation' algorithm with 3-5-1 architect gave the best prediction, and it showed a clear superiority over FCCD.

  16. Effect of packaging methods and crude aloe vera gel (Aloe vera barbadensis miller) on the storage quality of enrobed goat meat bites.

    Science.gov (United States)

    Jairath, Gauri; Chatli, Manish K; Sahoo, Jhari; Biswas, Ashim K

    2015-06-01

    The storage stability of enrobed goat meat bites (EGMB) incorporated with 3 % crude aloe vera (AV) gel was evaluated under aerobic (T-1; unenrobed control product, T-2; enrobed AV treated product) and modified atmospheric packaging (MAP, 50:50, CO2 and N2) (T-3; unenrobed control product, T-4; enrobed AV treated product) at 4 ± 1 °C for 42 days on the basis of physico-chemical, microbiological and sensory attributes. The pH value was higher, whereas water activity (aW) was lower in enrobed and MAP product. Thiobarbituric acid reacting substances (TBARS) and free fatty acid (FFA) values were significantly (P Standard Plate Count (SPC) was significantly (P < 0.05) lower in MAP products than aerobic packaged products. Results concluded that EGMB treated with AV gel can be successfully stored more than 42 days under MAP conditions without affecting its physico-chemical, textural, microbiological and sensory attributes.

  17. Effect of packaging methods and crude aloe vera gel (Aloe vera barbadensis miller) on the storage quality of enrobed goat meat bites.

    Science.gov (United States)

    Jairath, Gauri; Chatli, Manish K; Sahoo, Jhari; Biswas, Ashim K

    2015-06-01

    The storage stability of enrobed goat meat bites (EGMB) incorporated with 3 % crude aloe vera (AV) gel was evaluated under aerobic (T-1; unenrobed control product, T-2; enrobed AV treated product) and modified atmospheric packaging (MAP, 50:50, CO2 and N2) (T-3; unenrobed control product, T-4; enrobed AV treated product) at 4 ± 1 °C for 42 days on the basis of physico-chemical, microbiological and sensory attributes. The pH value was higher, whereas water activity (aW) was lower in enrobed and MAP product. Thiobarbituric acid reacting substances (TBARS) and free fatty acid (FFA) values were significantly (P < 0.05) lower in MAP packaged (T-3) and AV treated products (T-2 and T-4) products than aerobic packaged (T-1), however it followed an increasing trend in all the products throughout storage. Instrumental colour and textural profile attributes were better maintained in MAP products than others. The sensory panellists graded T-4 'good to very good' even on Day 42, whereas T-1 was acceptable only up to 28 days. Standard Plate Count (SPC) was significantly (P < 0.05) lower in MAP products than aerobic packaged products. Results concluded that EGMB treated with AV gel can be successfully stored more than 42 days under MAP conditions without affecting its physico-chemical, textural, microbiological and sensory attributes. PMID:26028757

  18. Influence of drinking water containing Aloe vera (Aloe barbadensis Miller gel on growth performance, intestinal microflora, and humoral immune responses of broilers

    Directory of Open Access Journals (Sweden)

    Meisam Shokraneh

    2016-11-01

    Full Text Available Aim: The risk of bacteria resistance to specific antibiotics possibly by continuous subtherapeutical administration of antibiotic growth promoters (AGPs in poultry feed led to a ban on the use of AGP in poultry production. As a result of this ban, alternative substances for poultry growth promotion and disease prevention are being investigated, among which phytogenic and herbal products have received increased attention as natural additives because they have been accepted by consumers as natural additives. The effect of water supplementation of Aloe vera (AV as an AGP substitute on performance, intestinal microflora, and immune responses of broilers. Materials and Methods: The five experimental treatments were allocated to four replicates. The following treatments were applied (1 a basal broiler diet (C and normal drinking water, (2 0.5% AV gel in drinking water, (3 0.75% AV gel in drinking water, (4 1% AV gel in drinking water, and (5 diet C supplemented with flavophospholipol at 4.5 mg/kg and drinking normal water. Vaccines against influenza disease and sheep red blood cell (SRBC were administrated to immunological stimuli. The populations of Lactobacilli spp. and coliforms were enumerated in ileum. Results: Body weight of broilers supplemented with different levels of AV increased compared with control group (p<0.05. Birds supplemented with antibiotic had the best feed-to-gain ratio (F:G in different periods. Supplementation of 0.5% and 0.75% AV improved F:G entire experimental period compared with control group (p<0.05. Coliform bacteria were reduced in broilers supplemented with different levels of AV or antibiotic (p<0.05. The Lactobacilli spp. population in birds supplemented with 0.75%, 1% AV or antibiotic significantly was higher than other groups (p<0.05. Supplementation with 1% AV led to greater antibody titers against SRBC compared with other groups (p<0.05. Conclusion: These findings demonstrated a possibility of supplementing

  19. 库拉索芦荟和木立芦荟叶的形态结构及有效成分含量的比较%Comparative of Morphology and Effective Composition Between the Leaves of Aloe vera L. and Aloe arborescens Mill

    Institute of Scientific and Technical Information of China (English)

    李景原; 王太霞; 刘贺君; 李明泽; 刘本举; 代磊

    2008-01-01

    应用植物解剖学和植物化学相结合的方法比较研究了3年生库拉索芦荟(Aloe vera L.)和木立芦荟(Aloe arborescens Mill)的形态结构和芦荟素、芦荟多糖等有效成分的含量.研究结果表明:(1)库拉索芦荟茎极短,叶丛生,成熟叶片长60~80 cm,质量400~550 g;木立芦荟茎高50~70 cm,叶互生,成熟叶片长40~50 cm,质量100~150 g.(2)两种芦荟叶都由表皮、同化组织、贮水组织和维管束组成.库拉索芦荟叶的贮水组织占横切面的90%以上,而木立芦荟叶的贮水组织仅占横切面的70%.(3)库拉索芦荟叶中芦荟素含量为1.46%,芦荟多糖含量为3.56%,宜作为芦荟多糖的原料;木立芦荟叶中芦荟素含量为2.15%,芦荟多糖含量为2.58%,宜作为芦荟素等蒽醌类物质的原料.研究结果为芦荟的引种栽培、采收和产品加工提供了科学依据.

  20. Ultraviolet light absorption of an ophthalmic formulation with Aloe extracts.

    Science.gov (United States)

    Ji, Yimei; Jia, Jicheng

    2009-09-01

    Aloin and polysaccharide present in extracts of Aloe arborescens Miller were formulated into a binary solution to protect eyes from bacterial infection and ultraviolet radiation (UVR). The UVR absorption spectrum was recorded from 190 to 440 nm using a UV spectrometer. The physical properties of the product were examined in terms of its appearance, odor, pH, viscosity, density, refractive index, and stability. The binary solution exhibited three absorption peaks in the UVA, B and C regions, respectively. Such UV absorption capability was attributed to the phenolic chromophores pertaining to aloin. The present study suggested that the formulated binary solution has potential application as an UV absorption agent with built-in antimicrobial activity. PMID:19831035

  1. Chemical and physical properties of aloe vera (Aloe barbadensis Miller) gel stored after high hydrostatic pressure processing Propriedades químicas e físicas do gel de aloe vera (Aloe barbadensis Miller) armazenado após processamento sob alta pressão hidrostática

    OpenAIRE

    Karina Di Scala; Antonio Vega-Gálvez; Kong Ah-Hen; Yissleen Nuñez-Mancilla; Gipsy Tabilo-Munizaga; Mario Pérez-Won; Claudia Giovagnoli

    2013-01-01

    The aim of this study was to evaluate the influence of high hydrostatic pressure (150, 250, 350, 450, and 550 MPa), applied for 5 minutes, on antioxidant capacity, total phenolic content, color, firmness, rehydration ratio, and water holding capacity of aloe vera gel stored for 60 days at 4 °C. The analyzed properties of the pressurized gel showed significant changes after the storage period. The highest value of total phenolic content was found at 550 MPa. However, a decrease in the antioxid...

  2. Developmental anatomy and the anomalous structure of the stem in Aloe arborescens%木立芦荟茎的发育解剖及其异常结构的研究

    Institute of Scientific and Technical Information of China (English)

    李景原; 王太霞; 胡正海

    2003-01-01

    应用植物解剖学方法研究了木立芦荟(Aloe arborescens Mill.)茎的发育过程.研究结果表明,木立芦荟茎的发育包括原分生组织、初生分生组织、初生结构和次生生长4个发育阶段.原分生组织具有典型分生组织的细胞特征;初生分生组织包括原表皮、基本分生组织和原形成层束.初生结构由表皮、薄壁组织和维管束组成.初生维管束为外韧有限维管束,分散于薄壁组织内.次生加厚分生组织起源于正常的散生维管束中柱外侧的薄壁组织细胞.次生加厚分生组织切向分裂,向外侧产生的细胞分化成薄壁组织;向内产生的细胞,一部分细胞分化成为薄壁组织细胞,称为结合组织,另一部分细胞则分化成为次生周木维管束,分散于结合组织中.由表皮之内的一层薄壁组织细胞恢复细胞分裂能力,进行切向分裂,以后形成周皮.木立芦荟茎初生结构阶段的增粗主要是基本分生组织和薄壁组织细胞的分裂和体积增大的结果.在老茎中,茎的增粗主要是由次生加厚分生组织进行细胞分裂及其衍生细胞体积增大的结果.

  3. 农杆菌介导法将bFGF基因转入木立芦荟的初步研究%Research on bFGF Gene Transferred into the Aloe arborescens Mill.by Mediated Agrobacterium tume faciens

    Institute of Scientific and Technical Information of China (English)

    刘思言; 姚丹; 关淑艳; 王丕武

    2011-01-01

    In this paper, bFGF gene was transfered into Aloe arborescens Mill.by mediated Agrobacterium tumefaciens,and a optimizational genetic transformation system was established on base of influencing factors on the genetic transformation system.The sturdy individual stems was used as the explants,which were infected 25min by engineering bacteria EHA105 (OD=0.6-0.7), then cultured in MS+sucrose 10 g/L+acetosyringone 100 μmol/L for 3 days,then selected in MS+6- BA 3 mg/L+Cef 400 mg/L+Kan 80 mg/L for 60 days, then cultured in differential medium MS+ 6 - BA 2 mg/L+NAA 0.15 mg/L, then transplanted after rooting, bFGF gene was integrated into the plant genom by PCR and Southern testing.%利用农杆菌介导法将bFGF基因导入木立芦荟中,通过对农杆菌介导芦荟遗传转化影响因素的分析,建立了优化的芦荟转化体系.用继代培养获得的粗壮的芦荟单株茎段作为转化外植体,以OD=0.55~0.68的EHA105农杆菌工程菌液侵染25min,在MS+蔗糖10g/L+100~mol/L乙酰丁香酮的共体培养基上培养3d,在MS+6一BA 3mg/L+头孢霉素400mg/L+卡那霉素80 mg/L的筛选培养基上培养60 d,然后转至MS+6一BA 2 mg/L+NAA 0.15 mg/L的分化培养基进行培养,生根后移栽.通过PCR初步检测,并经Southern杂交进一步证明外源基因bFGF已经整合到芦荟的基因组中.

  4. Chemical and physical properties of aloe vera (Aloe barbadensis Miller gel stored after high hydrostatic pressure processing Propriedades químicas e físicas do gel de aloe vera (Aloe barbadensis Miller armazenado após processamento sob alta pressão hidrostática

    Directory of Open Access Journals (Sweden)

    Karina Di Scala

    2013-03-01

    Full Text Available The aim of this study was to evaluate the influence of high hydrostatic pressure (150, 250, 350, 450, and 550 MPa, applied for 5 minutes, on antioxidant capacity, total phenolic content, color, firmness, rehydration ratio, and water holding capacity of aloe vera gel stored for 60 days at 4 °C. The analyzed properties of the pressurized gel showed significant changes after the storage period. The highest value of total phenolic content was found at 550 MPa. However, a decrease in the antioxidant capacity was observed for all pressurized gel samples when compared to the control sample (p O objetivo deste estudo foi avaliar o efeito da aplicação de altas pressões hidrostáticas (150, 250, 350, 450 e 550 MPa aplicadas durante 5 minutos sobre a atividade antioxidante, concentração de polifenóis totais, cor, firmeza, taxa de reidratação e capacidade de retenção de água do gel de aloe vera armazenado durante 60 dias a 4 °C. As propriedades analisadas do gel pressurizado mostraram mudanças significativas depois de armazenadas. Para pressões de 550 Mpa, registrou-se o maior aumento de polifenóis totais. No entanto, observou-se uma diminuição da capacidade antioxidante em todas as amostras, em comparação com a amostra não tratada (p < 0,05. As alterações de cor foram menores para pressões entre 150 e 250 MPa. A aplicação de altas pressões hidrostáticas diminuiu a firmeza do gel, registrando-se o menor valor para 150 MPa (p < 0,05. Por outro lado, o tratamento sem pressão mostrou uma maior perda de firmeza, indicando que o tratamento por altas pressões conserva esta propriedade. A aplicação de altas pressões evidenciou modificações da matriz do alimento, avaliadas como taxa de reidratação e capacidade de retenção de água.

  5. Inhibitory effects of aloe carboxypeptidase fraction on streptozotocin-induced enhancement of vascular permeability in the pancreatic islets.

    Science.gov (United States)

    Beppu, H; Shimpo, K; Chihara, T; Tamai, I; Nomoto-Yamaji, S; Ozaki, S; Ito, S; Kuzuya, H

    2006-01-01

    The protective actions of components isolated from Aloe arborescens Miller var. natalensis Berger (Kidachi aloe in Japanese) on streptozotocin (Sz)-induced necrosis of B cells in the pancreatic islets of the mouse were investigated to clarify its action mechanism involved in anti-diabetic effects. In this experiment, phenol low molecular weight components of aloin and aloin A that were anti-oxidants and derived from the leaf skin or pulp extract, an aloe carboxypeptidase fraction that is a inhibitor of enhanced vascular permeability and a glycoprotein component that decreases blood glucose were tested with mice precedently administered with Sz which is known as a cytotoxin specific to B cells. The results showed that the treatment group receiving Sz followed by the aloe carboxypeptidase fraction increased the inhibition of dye leakage by 75.8% (paloe carboxypeptidase fraction group also increased the inhibition effect by 68.4% (paloe-derived protease known to inhibit the acetic acid-related enhancement of intraperitoneal vascular permeability in mice. Further, the elevation of blood glucose in Sz-induced diabetic mice intraperitoneally given the aloe carboxypeptitase fraction was significantly (p<0.01-0.001) restrained at 3, 7 and 14 days after the injection as compared to the control group given solvent only. The results of this experiment suggested that the inhibitory effect on the enhancement of vascular permeability related to the vascular acute inflammatory response at Sz-induced lesions of pancreatic islets was involved in the action mechanism of this enzyme. PMID:16360933

  6. Antidiabetic effects of Aloe ferox and Aloe greatheadii var. davyana leaf gel extracts in a low-dose streptozotocin diabetes rat model

    OpenAIRE

    Botes, Lisa; Islam, Md. Shahidul; Loots, Du Toit; Pieters, Marlien

    2011-01-01

    The medicinal use and commercialisation of the plants Aloe ferox and Aloe greatheadii are primarily based on research done on Aloe vera and Aloe arborescens. Consequently, in this study we investigated the possible antidiabetic effects of ethanol extracts of A. ferox and A. greatheadii var. davyana leaf gel in a streptozotocin (STZ)-induced type 2 diabetes rat model. Fifty male Wistar rats, weighing 200 g – 250 g, were randomly divided into five groups of n = 10: normal control rats, diabetic...

  7. In vivo skin hydration and anti-erythema effects of Aloe vera, Aloe ferox and Aloe marlothii gel materials after single and multiple applications

    OpenAIRE

    Fox, Lizelle T.; Jeanetta du Plessis; Minja Gerber; Sterna van Zyl; Banie Boneschans; Josias H. Hamman

    2014-01-01

    To investigate the skin hydrating and anti-erythema activity of gel materials from Aloe marlothii A. Berger and A. ferox Mill. in comparison to that of Aloe barbadensis Miller (Aloe vera) in healthy human volunteers. Materials and Methods: Aqueous solutions of the polisaccharidic fractions of the selected aloe leaf gel materials were applied to the volar forearm skin of female subjects. The hydration effect of the aloe gel materials were measured with a Corneometer ® CM 825, Visioscan ® VC 98...

  8. Antidiabetic effects of Aloe ferox and Aloe greatheadii var. davyana leaf gel extracts in a low-dose streptozotocin diabetes rat model

    OpenAIRE

    Lisa Botes; Md Shahidul Islam; Marlien Pieters; Du Toit Loots

    2011-01-01

    The medicinal use and commercialisation of the plants Aloe ferox and Aloe greatheadii are primarily based on research done on Aloe vera and Aloe arborescens. Consequently, in this study we investigated the possible antidiabetic effects of ethanol extracts of A. ferox and A. greatheadii var. davyana leaf gel in a streptozotocin (STZ)-induced type 2 ...

  9. Study on the thermal instability of the active components in the gel of aloe arborescens Miller%木立芦荟凝胶活性成分的热不稳定性研究

    Institute of Scientific and Technical Information of China (English)

    冯咏梅; 王长海; 江涛; 常秀莲

    2005-01-01

    采用薄层层析法(TLC)测定木立芦荟凝胶汁中芦荟苷的含量,研究了芦荟苷的热不稳定性:用Bradford法测定了木立芦荟凝胶汁中蛋白质的热不稳定性.结果表明,加热温度越高,时间越长,芦荟苷和蛋白质的热稳定性越差;对结果进行双因素方差分析表明,时间对芦荟苷和蛋白质含量的影响比温度更显著,因此,若以芦荟苷和蛋白质为目标产物,则不宜采用长时间热处理来提取.

  10. ИССЛЕДОВАНИЕ ХИМИЧЕСКОГО СОСТАВА АЛОЕ ДРЕВОВИДНОГО (ALOE ARBORESCENS MILL.)

    OpenAIRE

    Оленников, Даниил; Зилфикаров, Ифрат; Ибрагимов, Тимур

    2010-01-01

    Проведено химическое исследование алоэ древовидного (Aloe arborescens Mill., сем. Asphodelaceae) с целью определения особенностей накопления каротиноидов, хлорофиллов, углеводов и фенольных соединений в различных частях листа, а также в зависимости от возраста листьев. В составе фотосинтетических пигментов установлено присутствие виолаксантина, криптоксантина, лютеина, β-зеакаротина, β-каротина, хлорофиллов а, b и феофетинов а, b; наибольшее содержание каротиноидов и хлорофиллов отмечено в эп...

  11. ХИМИЧЕСКИЙ СОСТАВ СОКА АЛОЭ ДРЕВОВИДНОГО (ALOE ARBORESCENS MILL.) И ЕГО АНТИОКСИДАНТНАЯ АКТИВНОСТЬ (IN VITRO)

    OpenAIRE

    Оленников, Даниил; Зилфикаров, Ифрат; Ибрагимов, Тимур; Торопова, Анюта; Танхаева, Лариса

    2010-01-01

    Проведено исследование химического состава сока алоэ древовидного (Aloe arborescens Mill., сем. Asphodelaceae), в ходе которого выявлено присутствие в нем органических кислот (яблочная кислота), аминокислот (доминируют Glu, Gly, Ser), свободных углеводов (глюкоза, сахароза, фруктоза), полисахаридов (пектиновые вещества), фенольных соединений. С использованием метода ВЭЖХ выявлено наличие в соке A. arborescens алоэнина, алоинов А и В и впервые эскулетина, умбеллиферона и ванилиновой кислоты. И...

  12. Effect of aloe lectin on deoxyribonucleic acid synthesis in baby hamster kidney cells.

    Science.gov (United States)

    Yagi, A; Machii, K; Nishimura, H; Shida, T; Nishioka, I

    1985-05-15

    A homogeneous glycoprotein (mol. wt 40,000) containing 34% carbohydrate was isolated from Aloe arborescens var. natalensis. At a concentration of 5 micrograms/ml, this glycoprotein was shown to stimulate deoxyribonucleic acid (DNA) synthesis in baby hamster kidney (BHK) cells and to have the properties of a lectin which reacts with sheep blood cells. The chemical and physical properties of the glycoprotein (aloe lectin) are also discussed. PMID:3996544

  13. Acute hepatitis induced by an Aloe vera preparation: A case report

    Institute of Scientific and Technical Information of China (English)

    Christian Rabe; Annemarie Musch; Peter Schirmacher; Wolfgang Kruis; Robert Hoffmann

    2005-01-01

    AIM: Aloe vera, plant extracts of Aloe barbadensis miller,is widely used in phytomedicine. The first case of acute hepatitis due to this compound was described.METHODS: Description of a clinical case.RESULTS: Hepatitis in a 57-year old female could be linked to the ingestion of Aloe barbadensis miller compounds. The patient's hepatitis resolved completely after discontinuing this medication.CONCLUSION: The case emphasizes the importance of considering phytopharmaceutical over-the-counter drugs as causative agents of hepatitis.

  14. New ceramides from Acnistus arborescens

    Energy Technology Data Exchange (ETDEWEB)

    Maia, Ana Isabel V.; Veras, Maria Leopoldina; Braz-Filho, Raimundo; Silveira, Edilberto R.; Pessoa, Otilia Deusdenia L., E-mail: opessoa@ufc.b [Universidade Federal do Ceara (UFC), Fortaleza, CE (Brazil). Dept. de Quimica Organica e Inorganica; Lopes, Norberto P. [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Ciencias Farmaceuticas. Dept. de Fisica e Quimica

    2010-07-01

    Two new ceramides, N-(4-hydroxyphenethyl)octacosamide (1) and rel-(2S,3S,4R,16E)-2- [(2'R)-2'-hydroxynonadecanoylamino]-heneicosadec-16-ene-1,3,4-triol (2) were isolated from the EtOH extract of Acnistus arborescens. The structures were elucidated by spectroscopic (1D and 2D NMR experiments, HR-ESI-MS, LR-MS and IR) methods. (author)

  15. Lipoma arborescens: diagnosis and image; Lipoma arborescens: diagnostico e imagem

    Energy Technology Data Exchange (ETDEWEB)

    Goncalves, Marcela; Len, Claudio Arnaldo; Terreri, Maria Teresa Ramos Ascencao [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Setor de Reumatologia Pediatrica; Fernandes, Artur da Rocha Correa [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Dept. de Diagnostico por Imagem; Hilario, Maria Odete Esteves [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Alergia, Imunologia e Reumatologia]. E-mail: odetehilario@terra.com.br

    2004-08-01

    Lipoma arborescens is an intraarticular lesion of unknown etiology, consisting of a chronic villous fat proliferation of the synovial membrane. The disease has occasionally been associated with diabetes mellitus, degenerative diseases, juvenile rheumatoid arthritis and also rheumatoid arthritis. The diagnosis relies on magnetic resonance imaging evaluation and synovial biopsy. We report a case of a 8-year-old girl with a two year history of bilateral swelling of the knees and elbows. The patient had improvement of the arthritis after starting treatment with conventional drugs. (author)

  16. [Ultracytochemical studies of aloin in Aloe arborescens leaves].

    Science.gov (United States)

    Liao, Hai Min; Shen, Zong Gen; Sheng, Xian Yong; Hu, Zheng Hai

    2006-02-01

    Lead acetate precipitation method was used for ultracytochemical localization of aloin. The processes of aloin production, transport and storage were studied by transmission electron microscope. Results showed that aloin was produced in the plastids of the assimilating tissue. The aloin was transported through the plastid membrane to the surrounding endoplasmic reticulum and enveloped in the vesicles by the endoplasmic reticulum elements, the vesicles approached and later fused with the plasmalemma. Some vesicles of the plastid membrane directly fused with the plasmalemma. The vesicles released their contents into the apoplast through exocytosis, and finally reached the vascular bundle sheath by apoplastic translocation. Aloin was transported to the internal tangential wall of vascular bundle sheath cell through endoplasmic reticulum vesicles, and reached the cytoplasm of aloin cell by means of plasmodesmata. Finally, aloin was stored in the vacuoles of aloin cell. PMID:16944572

  17. Aloe vera leaf gel: a review update.

    Science.gov (United States)

    Reynolds, T; Dweck, A C

    1999-12-15

    Research since the 1986 review has largely upheld the therapeutic claims made in the earlier papers and indeed extended them into other areas. Treatment of inflammation is still the key effect for most types of healing but it is now realized that this is a complex process and that many of its constituent processes may be addressed in different ways by different gel components. A common theme running though much recent research is the immunomodulatory properties of the gel polysaccharides, especially the acetylated mannans from Aloe vera, which are now a proprietary substance covered by many patents. There have also been, however, persistent reports of active glycoprotein fractions from both Aloe vera and Aloe arborescens. There are also cautionary investigations warning of possible allergic effects on some patients. Reports also describe antidiabetic, anticancer and antibiotic activities, so we may expect to see a widening use of aloe gel. Several reputable suppliers produce a stabilized aloe gel for use as itself or in formulations and there may be moves towards isolating and eventually providing verified active ingredients in dosable quantities PMID:10624859

  18. Aloe vera

    Energy Technology Data Exchange (ETDEWEB)

    Klein, A.D.; Penneys, N.S.

    1988-04-01

    We review the scientific literature regarding the aloe vera plant and its products. Aloe vera is known to contain several pharmacologically active ingredients, including a carboxypeptidase that inactivates bradykinin in vitro, salicylates, and a substance(s) that inhibits thromboxane formation in vivo. Scientific studies exist that support an antibacterial and antifungal effect for substance(s) in aloe vera. Studies and case reports provide support for the use of aloe vera in the treatment of radiation ulcers and stasis ulcers in man and burn and frostbite injuries in animals. The evidence for a potential beneficial effect associated with the use of aloe vera is sufficient to warrant the design and implementation of well-controlled clinical trials. 27 references.

  19. In Vitro Antioxidant Effects of Aloe barbadensis Miller Extracts and the Potential Role of These Extracts as Antidiabetic and Antilipidemic Agents on Streptozotocin-Induced Type 2 Diabetic Model Rats

    Directory of Open Access Journals (Sweden)

    Md. Ibrahim Khalil

    2012-11-01

    Full Text Available In this study, the total phenolic and flavonoid contents, the 2,2-diphenyl-1-picryl hydrazyl (DPPH radical scavenging ability and the ferric reducing power (FRAP of Aloe vera were measured to determine the antioxidant activity of this species. The in vivo antidiabetic effects of the plant were also investigated using streptozotocin-induced type 2 diabetic model rats that were divided into five groups based on the treatment received: (1 water (WC; (2 glibenclamide; (3 concentrated gel extract (Gel-C; (4 ethanol (80% gel extract (Gel-Et; and (5 ethanol (80% skin extract of Aloe vera (Skin-Et. Skin-Et, which contained the highest level of total phenolics (62.37 ± 1.34 mggallic acid/kg and flavonoids (20.83 ± 0.77 mg/kg, exhibited the highest scavenging activity (85.01 ± 0.52% and the greatest reducing power (185.98 ± 0.41 µM, indicating that the skin contained the highest level of antioxidants. The oral consumption of Gel-Et for 4 weeks a caused significant reduction in the fasting serum glucose levels of the rats. The rats in the Gel-C-, Gel-Et- and Skin-Et-treated groups experienced a reduction in their total cholesterol levels by 11%, 17% and 25%, respectively and a reduction in their LDL cholesterol levels by 45%, 3% and 69%, respectively. The in vivo experimental antioxidant parameter MDA is strongly correlated with the in vitro antioxidant parameters of flavonoids and polyphenols, namely the DPPH and FRAP values (r = 0.94, 0.92, 0.93, 0.90, thus confirming the antioxidant potential of the Aloe vera extracts.

  20. [Identification of Aloe species by random amplified polymorphic DNA (RAPD) analysis].

    Science.gov (United States)

    Shioda, Hiroko; Satoh, Kanako; Nagai, Fumiko; Okubo, Tomoko; Seto, Takako; Hamano, Tomoko; Kamimura, Hisashi; Kano, Itsu

    2003-08-01

    Juice and integument of leaves of 3 Aloe species, Aloe vera, A. ferox and A. africana, are not allowed to be used as food according to the Pharmaceutical Affairs Law in Japan. On the other hand, whole leaves of A. arborescens can be used as food. The present study was designed to distinguish Aloe species by random amplified polymorphic DNA (RAPD) analysis. DNA was isolated from fresh and dried leaves of the 4 Aloe species. Five out of 32 different 10-mer primers examined were useful for analysis. By comparison of the characteristic bands of PCR products on agarose gel, it was possible to distinguish the 4 species. Thus, the botanical species of Aloe in commercial food products can be identified by RAPD analysis. PMID:14606430

  1. Bilateral lipoma arborescens of the bicipitoradial bursa

    International Nuclear Information System (INIS)

    A 37-year-old military mechanic presented to our institution with a chronic history of a slowly enlarging left elbow antecubital fossa mass. There was no history of other chronic illness or trauma. Magnetic resonance imaging (MRI) and excisional biopsy revealed fatty villi and synovial inflammation within the left bicipitoradial bursa, consistent with lipoma arborescens. Four years later the patient presented with a 6-month history of swelling at the antecubital fossa of the opposite elbow. Diagnostic computed tomography and MRI examinations were performed. The surgical and pathologic findings confirmed the imaging diagnosis of lipoma arborescens at the right bicipitoradial bursa. (orig.)

  2. Aloe vera in dermatology: a brief review.

    Science.gov (United States)

    Feily, A; Namazi, M R

    2009-02-01

    Aloe vera Linne or aloe barbadensis Miller is a succulent from the Aloe family (400 different species), a tropical plant which is easily grown in hot and dry climates and widely distributed in Asia, Africa and other tropical areas. The use of aloe vera is being promoted for a large variety of conditions. The aim of this systematic review was to summarize all dermatology-oriented in vitro and in vivo experiments and clinical trials on aloe vera preparations. Extensive literature search were carried out to identify all in vitro and in vivo studies as well as clinical trials on the subject. Data were extracted from these in a predefined standardized manner. Forty studies were located. The results suggest that oral administration of aloe vera in mice is effective on wound healing, can decrease the number and size of papillomas and reduce the incidence of tumors and leishmania parasitemia by >90% in the liver, spleen, and bone marrow. Topical application of aloe vera is not an effective prevention for radiation-induced injuries and has no sunburn or suntan protection. It can be effective for genital herpes, psoriasis, human papilloma virus, seborrheic dermatitis, aphthous stomatitis, xerosis, lichen planus, frostbite, burn, wound healing and inflammation. It can also be used as a biological vehicle and an anti-microbial and antifungal agent and also as a candidate for photodynamic therapy of some kinds of cancer. Even though there are some promising results with the use of aloe vera for diverse dermatologic conditions, clinical effectiveness of oral and topical aloe vera is not sufficiently and meticulously explored as yet.

  3. [Effects of aloe extracts, aloctin A, on gastric secretion and on experimental gastric lesions in rats].

    Science.gov (United States)

    Saito, H; Imanishi, K; Okabe, S

    1989-05-01

    Effect of aloctin A, glycoprotein isolated from leaves of Aloe arborescens MILL, on gastric secretion and on acute gastric lesions in rats were examined. Aloctin A given intravenously dose-dependently inhibited the volume of gastric juice, acid and pepsin output in pylorus-ligated rats. Aloctin A given intravenously significantly inhibited the development of Shay ulcers and indomethacin-induced gastric lesions in rats. It also inhibited water-immersion stress lesions induced in pylorus-ligated rats. PMID:2625663

  4. Antifungal effects of different plant extracts and their major components of selected aloe species.

    Science.gov (United States)

    Ali, M I; Shalaby, N M; Elgamal, M H; Mousa, A S

    1999-08-01

    Different extracts of both fresh and dry leaves of Aloe eru A. Berger, A. vera L. Webb & Berth and A. arborescens Mill. were screened for their antifungal activity against Aspergillus niger, Cladosporium herbarum and Fusarium moniliforme. The toxicity of the isolated pure components were evaluated on the tested fungi. A comparative chromatographic study was performed to differentiate between natural components existing in various fractions and extracts of Aloe species and specific spray reagents were used for the detection of anthraquinones in the isolated components. PMID:10441780

  5. Aloe vera

    OpenAIRE

    González Freijo, Mariana

    2014-01-01

    El Aloe Vera posee importantes propiedades curativas, entre las cuales podemos nombrar su capacidad como regenerador celular, su poder como desintoxicante, rehidratante y cicatrizante, su capacidad analgésica y antiinflamatoria, su poder antiséptico, antibiótico, fungicida y antivírico en algunos casos y por último, su capacidad como inmunomodulador, mejorando los niveles de anticuerpos en el organismo con su ingesta Objetivo: Determinar el grado de información sobre las propie...

  6. Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review.

    Science.gov (United States)

    Radha, Maharjan H; Laxmipriya, Nampoothiri P

    2015-01-01

    Aloe vera ( lú huì) is well known for its considerable medicinal properties. This plant is one of the richest natural sources of health for human beings coming. The chemistry of the plant has revealed the presence of more than 200 different biologically active substances. Many biological properties associated with Aloe species are contributed by inner gel of the leaves. Most research has been centralized on the biological activities of the various species of Aloe, which include antibacterial and antimicrobial activities of the nonvolatile constituents of the leaf gel. Aloe species are widely distributed in the African and the eastern European continents, and are spread almost throughout the world. The genus Aloe has more than 400 species but few, such as A. vera, Aloe ferox, and Aloe arborescens, are globally used for trade. A. vera has various medicinal properties such as antitumor, antiarthritic, antirheumatoid, anticancer, and antidiabetic properties. In addition, A. vera has also been promoted for constipation, gastrointestinal disorders, and for immune system deficiencies. However, not much convincing information is available on properties of the gel. The present review focuses on the detailed composition of Aloe gel, its various phytocomponents having various biological properties that help to improve health and prevent disease conditions. PMID:26151005

  7. Semen characteristics and sperm morphological studies of the West African Dwarf Buck treated with Aloe vera gel extract

    OpenAIRE

    Oyeyemi Matthew Olugbenga; Samuel Gbadebo Olukole; Ajayi Tolulope Adeoye

    2011-01-01

    Background: Aloe vera (Aloe barbadensis miller) is an evergreen perennial plant widely used in modern herbal practice and is often available in proprietary herbal preparations.Objective: This study was designed to investigate the semen picture and spermatozoa morphology of West African Dwarf (WAD) bucks treated with Aloe vera extract.Materials and Methods: Twelve sexually matured WAD bucks, weighing between 11 and 15 kg, were used for the study. The bucks were first used as control (pre-treat...

  8. Semen characteristics and sperm morphological studies of the West African Dwarf Buck treated with Aloe vera gel extract

    OpenAIRE

    Olugbenga, Oyeyemi Matthew; Olukole, Samuel Gbadebo; Adeoye, Ajayi Tolulope; Adejoke, Adeniji Deborah

    2011-01-01

    Background: Aloe vera (Aloe barbadensis miller) is an evergreen perennial plant widely used in modern herbal practice and is often available in proprietary herbal preparations. Objective: This study was designed to investigate the semen picture and spermatozoa morphology of West African Dwarf (WAD) bucks treated with Aloe vera extract. Materials and Methods: Twelve sexually matured WAD bucks, weighing between 11 and 15 kg, were used for the study. The bucks were first used as control (pre-tre...

  9. Identification and discrimination of three common Aloe species by high performance liquid chromatography-tandem mass spectrometry coupled with multivariate analysis.

    Science.gov (United States)

    Zhao, Yan; Sun, Ya Nan; Lee, Min Jung; Kim, Young Ho; Lee, Wonjae; Kim, Kyeong Ho; Kim, Kyung Tae; Kang, Jong Seong

    2016-09-15

    Aloe arborescens, Aloe barbadensis and Aloe ferox are the most widely cultivated and used among 500 aloe species due to their potent bioactivity. However, the difference of aloe species is neglected and labeled only one name Aloe in the market without specifying aloe species discrimination in general. Furthermore, differences in bioactivity and side effects from different aloe species have not been well investigated. This study develops an effective method for simultaneous qualitative and quantitative determination of three common aloe species using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) and high performance liquid chromatography-diode array detection (HPLC-DAD). The extraction conditions were optimized by response surface methodology (RSM) based on methanol concentration, extraction time and solvent-to-material ratio. A partial least squares-discriminant analysis (PLS-DA) was used to identify the three aloe species. The developed HPLC-MS/MS method coupled with multivariate analysis can be applied to discriminate three aloe species successfully. PMID:27494280

  10. The Genus Aloe: Phytochemistry and Therapeutic Uses Including Treatments for Gastrointestinal Conditions and Chronic Inflammation.

    Science.gov (United States)

    Cock, I E

    2015-01-01

    Plants of the genus Aloe have perhaps the longest recorded history of medicinal usage and are amongst the most widely used plants for traditional medicinal purposes worldwide. Aloe vera, Aloe ferox, Aloe arborescens and Aloe perryi are the best known and most widely used, but many other species are also used for their therapeutic properties. The Aloes have been used since ancient times, particularly for the treatment of microbial infections, gastrointestinal disorders and inflammatory conditions. In addition to their myriad uses in traditional therapeutics, the Aloes have also been used as components of cosmetic formulations, and in the food and beverage industries. Despite their wide acceptance, studies from different laboratories often report wide variations in the therapeutic bioactivities from within the same Aloe species, even when the same extraction procedures are used. Furthermore, leaves from individual Aloe plants within the same species may have widely varying levels of the bioactive phytochemicals. Phytochemical analyses have shown that many Aloe species contain various carbohydrate polymers (notably glucomannans) and a range of other low molecular weight phenolic compounds including alkaloids, anthraquinones, anthrones, benzene and furan derivatives, chromones, coumarins, flavonoids, phytosterols, pyrans and pyrones. There has been a wealth of information published about the phytochemistry and therapeutic potential of the Aloes (especially Aloe vera). Much of this has been contradictory. Intra- and interspecies differences in the redox state of the individual Aloe components and in the ratios of these components may occur between individual plants. These factors may all affect the physiological properties of Aloe extracts. Due to the structure and chemical nature of many of the Aloe phytochemicals, it is likely that many of the reported medicinal properties are due to antioxidant or prooxidant effects. The antioxidant/prooxidant activities of many Aloe

  11. [Distribution of anthraquinones in leaves of two Aloe species and their defence strategy].

    Science.gov (United States)

    Shen, Zonggen; Li, Jingyuan; Hu, Zhenghai

    2002-11-01

    Aloe plants are the succulents mainly distributed in arid or semi-arid desert in South Africa. TLC analysis indicated that Aole arborescens and Aloe hereroensis contained the high concentration of phenolic derivative metabolites, anthraquinones such as barbaloin, homonataloin, aloeresin and aloenin. In younger leaf, L3 of A. hereroensis, the average content of 4 anthraquinones reached 44.9% of the dry weight of exudates. The similar distribution of the anthraquinones in the two species were found, which showed that the youngest leaves had the highest content, the top part of each leaf had the highest content, and the basal part had the lowest content. Along leaf margin, the content was higher than that of central parts. However, some different distributions were also revealed and compared between the two species. It was inferred that the special distribution of anthraquinones in Aloe was a chemical defense strategy for protection themselves. PMID:12624988

  12. ИДЕНТИФИКАЦИЯ БИОЛОГИЧЕСКИ АКТИВНЫХ КОМПОНЕНТОВ ALOE ARBORESCENS MILLER

    OpenAIRE

    Рюшина, В.; Габрук, Н.; Шутеева, Т.

    2010-01-01

    В работе с помощью спектральных методов анализа была идентифицирована основная группа биологически-активных компонентов алоэ антраценпроизводные. Методом рентгенофлуоресцентного анализа определен минеральный состав листьев алоэ. В ряду растворителей (ацетон, этилацетат, водно-спиртовые смеси) определен оптимальный экстрагент для основной группы БАВ, проведена предварительная оценка антиоксидантной активности нативного сока алоэ....

  13. Isolation of Astilbin from Leaves of Cratoxylum Arborescens

    International Nuclear Information System (INIS)

    Phytochemicals studies was conducted on the leaves of Cratoxylum arborescens that has been collected from Post Brooke, Gua Musang, Kelantan, Malaysia. Traditionally, latex of the stem bark of C. arborescens is being used for the treatment of wound. Extraction of leaves of C. arborescens using organic solvents followed by purification using standard procedure of purification yielded known compound, astilbin. This compound was identified by NMR spectral data using various 2D-techniques and comparison with the literature data. Reports showed that this compound has a unique immunosuppressive activity, a selective inhibition against activated T lymphocytes. This characteristic of astilbin is beneficial for the treatment of human immune diseases. (author)

  14. Feeding mice with Aloe vera gel diminishes L-1 sarcoma-induced early neovascular response and tumor growth.

    Science.gov (United States)

    Kocik, Janusz; Bałan, Barbara Joanna; Zdanowski, Robert; Jung, Leszek; Skopińska-Różewska, Ewa; Skopiński, Piotr

    2014-01-01

    Aloe vera (Aloe arborescens, aloe barbadensis) is a medicinal plant belonging to the Liliaceae family. Aloe vera gel prepared from the inner part of Aloe leaves is increasingly consumed as a beverage dietary supplement. Some data suggest its tumor growth modulatory properties. The aim of the present study was to evaluate in Balb/c mice the in vivo influence of orally administered Aloe vera drinking gel on the syngeneic L-1 sarcoma tumor growth and its vascularization: early cutaneous neovascular response, tumor-induced angiogenesis (TIA test read after 3 days), and tumor hemoglobin content measured 14 days after L-1 sarcoma cell grafting. Feeding mice for 3 days after tumor cell grafting with 150 μl daily dose of Aloe vera gel significantly diminished the number of newly-formed blood vessels in comparison to the controls. The difference between the groups of control and Aloe-fed mice (150 μl daily dose for 14 days) with respect to the 14 days' tumor volume was on the border of statistical significance. No difference was observed in tumor hemoglobin content.

  15. Feeding mice with Aloe vera gel diminishes L-1 sarcoma-induced early neovascular response and tumor growth.

    Science.gov (United States)

    Kocik, Janusz; Bałan, Barbara Joanna; Zdanowski, Robert; Jung, Leszek; Skopińska-Różewska, Ewa; Skopiński, Piotr

    2014-01-01

    Aloe vera (Aloe arborescens, aloe barbadensis) is a medicinal plant belonging to the Liliaceae family. Aloe vera gel prepared from the inner part of Aloe leaves is increasingly consumed as a beverage dietary supplement. Some data suggest its tumor growth modulatory properties. The aim of the present study was to evaluate in Balb/c mice the in vivo influence of orally administered Aloe vera drinking gel on the syngeneic L-1 sarcoma tumor growth and its vascularization: early cutaneous neovascular response, tumor-induced angiogenesis (TIA test read after 3 days), and tumor hemoglobin content measured 14 days after L-1 sarcoma cell grafting. Feeding mice for 3 days after tumor cell grafting with 150 μl daily dose of Aloe vera gel significantly diminished the number of newly-formed blood vessels in comparison to the controls. The difference between the groups of control and Aloe-fed mice (150 μl daily dose for 14 days) with respect to the 14 days' tumor volume was on the border of statistical significance. No difference was observed in tumor hemoglobin content. PMID:26155093

  16. Millerism - an historical enigma?

    Directory of Open Access Journals (Sweden)

    Ingemar Lindén

    1975-01-01

    Full Text Available It is a wellknown fact in history that strong bias in the writers and a wishful thinking radically prevent the analysis of any event or religious activity. For this reason Catholic ecclesiastical writers of the old school distorted the role of Martin Luther and his movement; likewise the Radical Reformation fared badly in old handbooks, whether they were composed by Catholics or Lutherans. Again the same principle applies to many of the modern "sects" in America and in Europe. Millerism is an excellent case for illustrating this unfelicitious type of writing. The layman-evangelist William Miller (1782-1849 claimed that the world would never be converted; only the second coming of Christ could usher in the millennium. In order to obtain a better understanding of Millerism, the movement should be divided into three main periods, which differed in character. At first, Miller's own development needs to be ascertained. Though he lacked any thorough intellectual training and remained an autodidact, he nevertheless belonged to the wide range of middle class Yankees. To be sure, Miller lived not too far from the famous frontier in his youth, but despite preconceived ideas in some writers, Miller had his cultural roots in the built-up areas of a New England society. The second important stratum in his personality was the warm Baptist revivalism, which prevailed in his home. Deism and revivalism thus contended for the supremacy of his soul; admitting the later dominance of evangelical revivalism, reason and order continued to hold a place in his mental set-up.

  17. Recurrent Miller Fisher syndrome.

    Science.gov (United States)

    Madhavan, S; Geetha; Bhargavan, P V

    2004-07-01

    Miller Fisher syndrome (MFS) is a variant of Guillan Barre syndrome characterized by the triad of ophthalmoplegia, ataxia and areflexia. Recurrences are exceptional with Miller Fisher syndrome. We are reporting a case with two episodes of MFS within two years. Initially he presented with partial ophthalmoplegia, ataxia. Second episode was characterized by full-blown presentation characterized by ataxia, areflexia and ophthalmoplegia. CSF analysis was typical during both episodes. Nerve conduction velocity study was fairly within normal limits. MRI of brain was within normal limits. He responded to symptomatic measures initially, then to steroids in the second episode. We are reporting the case due to its rarity.

  18. Interview: Sarah Miller

    Directory of Open Access Journals (Sweden)

    Richelle E. Wescott

    2012-01-01

    Full Text Available While still an undergraduate, Sarah Miller served as the Architecture and Design Manager for Purdue’s INHome project, which constructed a self-sufficient solar home for the Department of Energy’s Solar Decathlon. Despite this being Purdue's first time participating in the international contest, the entry earned second place.

  19. MR imaging of lipoma arborescens and the associated lesions

    Energy Technology Data Exchange (ETDEWEB)

    Vilanova, J.C.; Barcelo, J.; Villalon, M. [Magnetic Resonance Unit, Ressonancia Girona, Clinica Girona (Spain); Aldoma, J.; Delgado, E. [Centre Diagnostic Pedralbes, Barcelona (Spain); Zapater, I. [Dept. of Radiology, Hospital de Palamos, Palamos, Girona (Spain)

    2003-09-01

    Objective: To describe the typical features of lipoma arborescens on MR imaging with pathologic correlation and to evaluate the associated lesions within the joints. Design and patients: The MR imaging findings of 32 patients with the diagnosis of lipoma arborescens of the knee (n=32) and shoulder (n=1) were reviewed. The diagnosis of lipoma arborescens was confirmed by the histologic findings in 12 cases and the other 21 cases were diagnosed by the characteristic MR imaging features. One patient had bilateral lipoma arborescens of the knee joint. Results: MR imaging showed a typical pattern of villous lipomatous proliferation of the synovium in all cases, as a diffuse pattern in 79% (26/33) of cases and as a dominant mass-like lesion in 21% (7/33) of cases. The associated MR pathology in the knee was (n=32): joint effusion (100%), degenerative changes (87%), meniscal tear (72%), synovial cysts (38%), bone erosions (25%), chondromatosis (13%), patellar subluxation (6%) and discoid meniscus (3%). In all cases except two there was associated pathology of the knee. MR imaging showed an associated rotator cuff tear in the lipoma arborescens of the shoulder. Conclusion: The characteristic MR features of lipoma arborescens allows an accurate diagnosis of this rare lesion, which is almost always associated with other chronic pathology of the joint in the elderly. (orig.)

  20. COMBINED APPLICATION OF TRIAAND POTASSIUM STIMULATES THE GEL CONTENT, MORPHOLOGICALAND BIOCHEMICAL CHARACTERISTICS OF ALOE VERA

    OpenAIRE

    SABA IQBAL , M. MASROOR A. KHAN; ZEBA H. KHAN

    2012-01-01

    Aloe barbadensis (A. barbadensis L.) Miller, commonly known as aloe vera is extensively used as a base element in preparation of medicine, cosmetics and food supplements. The objective of this study was to find out the stimulatory effect of varying levels of triacontanol (TRIA) in combination with different concentrations of potassium (K) on morphological and biochemical characteristics of aloe vera plants. Treatments included four levels of TRIA (10-0, 10-5, 10-6 and 10-7M) together three co...

  1. 芦荟醇提物对α-葡萄糖苷酶的抑制效果%Study on the inhibitory effect of aloe extracts on α-glucosidase activity

    Institute of Scientific and Technical Information of China (English)

    柴明艳

    2015-01-01

    The inhibitory effects of aloe extracts on α-glucosidase activity were investigated.The aloe with the best inhibitory effects on α-glucosidase was screened from 5 species,in order to obtain the functional composition of reducing the postprandial blood glucose.The best variety of aloe was determined according to the inhibition rate by α-glucosidase inhibitor screen model in vitro;and the type of enzyme inhibition was decided by enzyme concentration -response speed and L -B graphing method.Results showed that the ethanol extract of aloe arborescens miller showing the best effects had the highest inhibi-tion rate of 87.95%;aloe extract was noncompetitive inhibitor of α-glucosidase and showed dose -de-pendent relationship.The Km value of aloe extract was 0.442 mmol /L.The enzyme inhibition kinetics process curve showed the time of initial velocity of reaction was 18 min.It suggested that aloe containedα-glucosidase inhibitors with high effects,and could be developed for the treatment and prevention of diabetes and its complications.%为探讨芦荟醇提物对α-葡萄糖苷酶的抑制活性,从5种芦荟中筛选出对α-葡萄糖苷酶抑制效果最好的品种,以期从该芦荟中获得降低餐后血糖的功能成分。采用α-葡萄糖苷酶抑制剂体外筛选模型,通过抑制率高低确定抑制作用最好的芦荟品种,以酶浓度—反应速度及 Lin-eweaver -Burk 作图法确定酶抑制类型。结果发现,5种芦荟中木立芦荟醇提物抑制率为87.95%,效果最好;芦荟提取物是α-葡萄糖苷酶的非竞争性抑制剂,且呈剂量依赖性关系,其 Km 为0.442 mmol /L;酶抑制动力学进程曲线表明其反应初速度的时间为18 min。以上结果提示,芦荟中含有活性较高的α-葡萄糖苷酶抑制剂,可开发用于糖尿病及其并发症的治疗与预防。

  2. 芦荟罐头生产工艺%Main Process of Aloe Can

    Institute of Scientific and Technical Information of China (English)

    赵华

    2005-01-01

    芦荟是一种百合科草本植物,民间自古就有使用芦荟的记载。芦荟及其变种各类很多,目前在我国种植和加工较多的库拉索芦荟(Aloe Vera L.)。木立芦荟(A. arborescens Mill)和华芦荟(A.Varavia),还有少量的皂质芦荟和开谱敦芦荟等。

  3. Aloe Vera in Dentistry

    OpenAIRE

    Sujatha, G; Kumar, G. Senthil; Muruganandan, J; Prasad, T Srinivasa

    2014-01-01

    Aloe vera is a medicinal plant which has been used for thousands of years. The health benefits of aloe vera is well known and the dental uses of this plant is multiple. Interest is gathering among researchers regarding the use of this plant. Studies have proved the antiseptic, anti inflammatory, antiviral and antifungal properties of aloe vera and the use of this plant is proved beneficial. This plant is proved to be non allergic and very good in building up the immune system. Aloe vera is ga...

  4. SINDROME DE MILLER DIEKER.

    OpenAIRE

    María Corfio P.; Romina Romeo G.

    2007-01-01

    El síndrome de Miller Dieker es una patología genética pocofrecuente, descrita en 1963 para referirse al fenotipo específicoasociado a lisencefalia tipo I y anomalías craneofaciales. Suincidencia exacta se desconoce, pero la incidencia de todas laslisencefalias es alrededor de 1/100.000 recién nacidos (1). Seorigina por una delección o mutación en el cromosoma 17 p.13.3 específicamente el gen LIS1, responsable de un espectro deenfermedades que involucran la migración neuronal y que en sumáxim...

  5. Phytochemical constituents and in vitro radical scavenging activity of different Aloe species.

    Science.gov (United States)

    Lucini, Luigi; Pellizzoni, Marco; Pellegrino, Roberto; Molinari, Gian Pietro; Colla, Giuseppe

    2015-03-01

    The phytochemical profile of Aloe barbadensis Mill. and Aloe arborescens Mill. was investigated using colorimetric assays, triple quadrupole and time-of-flight mass spectrometry, focusing on phenolic secondary metabolites in the different leaf portions. Hydroxycinnamic acids, several characteristic anthrones and chromones, the phenolic dimer feralolide and flavonoids such as flavones and isoflavones were identified. The stable radical DPPH test and the ORAC assay were then used to determine the in vitro radical scavenging. The outer green rind was the most active, while the inner parenchyma was much less effective. The 5-methylchromones aloesin, aloeresin A and aloesone were the most active among the pure secondary metabolites tested. The results suggest that several compounds are likely to contribute to the overall radical scavenging activity, and indicate that leaf portion must be taken into account when the plant is used for its antioxidant properties. PMID:25306376

  6. Tenosynovial lipoma arborescens of the ankle in a child

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Guo-Shu; Hsu, Yi-Chih; Kao, Hung-Wen; Chen, Cheng-Yu [National Defense Medical Center, Department of Radiology, Tri-Service General Hospital, Taipei (Taiwan); Lee, Herng-Sheng [National Defense Medical Center, Department of Pathology, Tri-Service General Hospital, Taipei (Taiwan); Lee, Hsieh-Hsing [National Defense Medical Center, Department of Orthopedic Surgery, Tri-Service General Hospital, Taipei (Taiwan)

    2006-04-15

    Lipoma arborescens is a rare entity of the synovium and frequently occurs in the joints. Lipoma arborescens involving the synovial sheaths of the tendons is exceedingly rare. We report a case of a 12-year-old girl with lipoma arborescence affecting the synovial sheaths of the peroneal, posterior tibialis, and flexor tendons. Identification of the typical features of fat tissues in the proliferative synovium on MRI may help in making a correct diagnosis. The clinical presentation and MRI findings are described, and the entity is briefly reviewed. (orig.)

  7. Aloe vera in dentistry.

    Science.gov (United States)

    Sujatha, G; Kumar, G Senthil; Muruganandan, J; Prasad, T Srinivasa

    2014-10-01

    Aloe vera is a medicinal plant which has been used for thousands of years. The health benefits of aloe vera is well known and the dental uses of this plant is multiple. Interest is gathering among researchers regarding the use of this plant. Studies have proved the antiseptic, anti inflammatory, antiviral and antifungal properties of aloe vera and the use of this plant is proved beneficial. This plant is proved to be non allergic and very good in building up the immune system. Aloe vera is gaining popularity in dentistry as it is completely natural and there is no side effects being reported with its use. This paper gives an overview of the uses of this miracle plant and its uses in dentistry.

  8. Aloe vera in dentistry.

    Science.gov (United States)

    Sujatha, G; Kumar, G Senthil; Muruganandan, J; Prasad, T Srinivasa

    2014-10-01

    Aloe vera is a medicinal plant which has been used for thousands of years. The health benefits of aloe vera is well known and the dental uses of this plant is multiple. Interest is gathering among researchers regarding the use of this plant. Studies have proved the antiseptic, anti inflammatory, antiviral and antifungal properties of aloe vera and the use of this plant is proved beneficial. This plant is proved to be non allergic and very good in building up the immune system. Aloe vera is gaining popularity in dentistry as it is completely natural and there is no side effects being reported with its use. This paper gives an overview of the uses of this miracle plant and its uses in dentistry. PMID:25478478

  9. ALOS-2 initial results

    Science.gov (United States)

    Kankaku, Yukihiro; Suzuki, Shinichi; Shimada, Masanobu

    2015-10-01

    The Advanced Land Observing Satellite-2 (ALOS-2) was launched from Tanegashima Space Center by H-IIA rocket successfully on 24th May 2014. ALOS-2 carries the Phased Array type L-band Synthetic Aperture Radar-2 (PALSAR-2) as the state-of-the-art L-band SAR system which succeeds to PALSAR onboard ALOS. PALSAR-2 uses almost whole bandwidth allocated for L-band active sensor of Earth Exploration Satellites Service specified by the Radio Regulation in order to realize the high resolution observation, and also, it transmits more than 6 kW power for lower Noise Equivalent Sigma Zero using 180 TRMs driven by Gallium Nitride (GaN) amplifier which is the first use in space. Furthermore, because ALOS-2 carries the SAR system only, PALSAR-2 antenna can be mounted under the satellite body. It enables to observe right-/left-looking observation by satellite maneuvering. And the high accuracy orbit control to maintain the satellite within 500 m radius tube against the reference orbit enables high coherence for the InSAR processing. Using these new technologies, ALOS-2 has been operating to fulfill the mission requirements such as disaster monitoring and so on. This document introduces the initial result of ALOS-2 from the first year operation.

  10. SINDROME DE MILLER DIEKER.

    Directory of Open Access Journals (Sweden)

    María Corfio P.

    2007-12-01

    Full Text Available El síndrome de Miller Dieker es una patología genética pocofrecuente, descrita en 1963 para referirse al fenotipo específicoasociado a lisencefalia tipo I y anomalías craneofaciales. Suincidencia exacta se desconoce, pero la incidencia de todas laslisencefalias es alrededor de 1/100.000 recién nacidos (1. Seorigina por una delección o mutación en el cromosoma 17 p.13.3 específicamente el gen LIS1, responsable de un espectro deenfermedades que involucran la migración neuronal y que en sumáximo defecto genera esta patología (2. La delección se puededar en forma espontánea o secundaria a una traslocación crípticade los padres, existiendo en este último caso alto riesgo detransmisión (3.La anormalidad principal es el desarrollo incompleto del cerebrogenerado por un trastorno en la migración y proliferaciónneuronal, caracterizándose por agira y adelgazamiento cortical,asociado a hipoplasia del cuerpo calloso, cerebelo atrófico y calcificacionesen la línea media, que se manifiesta con un retardomental severo, hipotonía, trastorno de la deglución, epilepsiade difícil manejo y retardo en el crecimiento (4. Las malformacionescraneofaciales se caracterizan por microcefalia, estrechamientobitemporal, pliegues verticales en el centro de la frente alllorar, narinas evertidas, micrognatia y labio superior fino. Otrasanormalidades descritas son: criptorquidea, seno pilonidal, clinodactilia,surco transverso palmar y malformaciones genitourinariasque se relacionan con peor pronóstico (5. Evolucionancon un severo retardo mental y convulsiones que se traducen enuna mortalidad temprana a causa de infecciones pulmonares arepetición (1.El diagnóstico se basa en la sospecha clínica y se confirma a travésdel método Fluorescent in situ hybridization (FISH dirigidoa 17 p. 13.3, altamente específico y también útil para el diagnósticode familiares (6 y 7. Actualmente también se recomiendacomo screening en los casos de sospecha prenatal

  11. Lipoma arborescens of the knee: report of a case managed by arthroscopic synovectomy.

    Science.gov (United States)

    Franco, Michel; Puch, J M; Carayon, M J; Bortolotti, D; Albano, Laetitia; Lallemand, A

    2004-01-01

    We report a case of lipoma arborescens treated with an arthroscopic procedure. Lipoma arborescens is an uncommon pseudo-tumoral synovial lesion usually located in the suprapatellar pouch of the knee. This diagnosis should be considered, particularly in patients with chronic joint effusion. Magnetic resonance imaging confirms the lipomatous nature of the synovial proliferation. When limited to the anterior compartment of the knee, lipoma arborescens can be treated by arthroscopic synovectomy. PMID:14769527

  12. Biotransformation of aloenin, a bitter glucoside constituent of Aloe arborescens, by rats.

    Science.gov (United States)

    Hirata, T; Sakano, S; Suga, T

    1981-12-15

    Aloenin has been established to be 4-methoxy-6-(2-beta-D-glucopyranosyloxy-4-hydroxy-6-methylphenyl)-2-pyrone; it shows an inhibitory activity for gastric juice secretion. Rats metabolized it to 4-methoxy-6-(2,4-dihydroxy-6-methylphenyl)-2-pyrone, 2,5-dimethyl-7-hydroxychromone and glucose, which were excreted in the feces and the urine. The distribution of the radioactivity originating from 14C-labeled aloenin was studied. The tracer found in the kidney and the liver reached 60% of the amount administered 24 h after feeding and decreased rapidly in the next 24 h. PMID:7035211

  13. Aloe vera: Plant of Immortality

    OpenAIRE

    Sikarwar Mukesh S.; Patil M B; Bhat Vishnu; Sharma Shalini

    2010-01-01

    The Egyptians called Aloe the “Plant of Immortality” because it can live and even bloom without soil. Aloe has been used medicinally since at least the first century C.E. and continues to be used extensively worldwide.

  14. Osmo-air drying of aloe vera gel cubes.

    Science.gov (United States)

    Pisalkar, P S; Jain, N K; Jain, S K

    2011-04-01

    Aloe vera (Aloe barbadensis Miller) cubes of 12.5 × 12.5 × 12.5 mm thick were osmosed for 4 h in sugar syrup of 30, 40 and 50°Brix concentration and temperatures of 30 and 50°C at constant syrup to fruit ratio of 5:1. Osmosed and unosmosed aloe vera samples were hot air dried at 50, 60, 70 and 80°C with constant air velocity of 1.5 m/s. The water loss, solid gain and convective drying behaviour were recorded during experiments. It was observed that water loss and solid gain ranged from 39.2 to 71.3 and 2.7 to 6.3%, respectively during osmo-drying. The moisture diffusivity varied from 2.9 to 8.0 × 10(-9) m²/s and 2.7 to 4.6 × 10(-9) m²/s during air drying of osmosed and unosmosed aloe vera samples, respectively. Drying air temperature and osmosis as pre-treatment affected the water loss, solid gain, diffusivity at -p ≤ 0.01. PMID:21350589

  15. The addition of rosehip oil to Aloe gels improves their properties as postharvest coatings for maintaining quality in plum.

    Science.gov (United States)

    Martínez-Romero, Domingo; Zapata, Pedro J; Guillén, Fabián; Paladines, Diego; Castillo, Salvador; Valero, Daniel; Serrano, María

    2017-02-15

    The effect of Aloe vera gel (AV) and Aloe arborescens gel (AA) alone or in combination with rosehip oil (RO) at 2% on ethylene production, respiration rate, quality parameters, bioactive compounds and antioxidant activity during plum postharvest storage was studied. Coated plums showed a delay in ethylene production and respiration rate at 20°C and during cold storage and subsequent shelf life, the main effect being observed for those fruits coated with AA+RO. Quality parameters such as softening, colour and maturity index was also delayed during storage by the use of the coatings, which led to a 2-fold increase in plum storability. Accumulation of bioactive compounds was also delayed although at the end of the experiment the content of bioactive compounds was higher than those found for control fruits at the estimated shelf life. The most effective coating for maintaining plum quality and bioactive compounds was AA+RO. PMID:27664675

  16. In vivo diabetic wound healing effect and HPLC–DAD–ESI–MS/MS profiling of the methanol extracts of eight Aloe species

    Directory of Open Access Journals (Sweden)

    Abeer M. El Sayed

    2016-06-01

    Full Text Available Abstract Genus Aloe, Xanthorrhoeaceae, is well distributed all over Egypt, and many species have been used as medicinal plants; mainly reported to prevent cardiovascular diseases, cancer and diabetes. This study attempts to analyze the secondary metabolites in the methanol extract of the leaves of eight Aloe species; A. vera (L. Burm. f., A. arborescens Mill., A. eru A. Berger, A. grandidentata Salm-Dyck, A. perfoliata L., A. brevifolia Mill., A. saponaria Haw. and A. ferox Mill. growing in Egypt. For this aim HPLC–DAD–MS/MS in negative ion mode was used. Although belonging to the same genus, the composition of each species presented different particularities. Seventy one compounds were identified in the investigated Aloe species, of which cis-p-coumaric acid derivaties, 3,4-O-(E caffeoylferuloylquinic acid and caffeoyl quinic acid hexoside were the most common phenolic acids identified. Aloeresin E and isoaloeresin D, 2'-O-feruloylaloesin were the common anthraquinones identified. Lucenin II, vicenin II, and orientin were the common identified flavonoids in the investigated Aloe species. 6'-Malonylnataloin, aloe-emodin-8-O-glucoside, flavone-6,8-di-C-glucosides could be considered as chemotaxonomic markers for the investigated Aloe species. The eight Aloe species had significant anti-inflammatory activity, in addition to the significant acceleration of diabetic wound healing in rats following topical application of the methanol extracts of their leaves. This is the first simultaneous characterization and qualitative determination of multiple phenolic compounds in Aloe species from locally grown cultivars in Egypt using HPLC–DAD–MS/MS, which can be applied to standardize the quality of different Aloe species and the future design of nutraceuticals and cosmetic preparations.

  17. An Interview with Ron Miller.

    Science.gov (United States)

    Mercogliano, Chris; Becker, Ellen; Leue, Mary

    1998-01-01

    Ron Miller, founder of the journal "Holistic Education Review," discusses his intellectual background in humanistic psychology and historical studies, definition of holism in education, the holistic approach as an answer to the reductionist and fragmented modern era, founding of the journal as a form of activism, and the incremental nature of…

  18. Implementing the Kustin-Miller complex construction

    CERN Document Server

    Boehm, Janko

    2011-01-01

    The Kustin-Miller complex construction, due to A. Kustin and M. Miller, can be applied to a pair of resolutions of Gorenstein rings with certain properties to obtain a new Gorenstein ring and a resolution of it. It gives a tool to construct and analyze Gorenstein rings of high codimension. We describe the Kustin-Miller complex and its implementation in the Macaulay2 package KustinMiller, and explain how it can be applied to explicit examples.

  19. Strong enhancement of antioxidant activity of Aloe vera extracts by gamma irradiation

    International Nuclear Information System (INIS)

    The World Health Organization (WHO) has estimated that approximately 80% of individuals rely on traditional medicines. Among over 400 Aloe species, Aloe vera was the most accepted species for various medical, cosmetic and neutraceutical purposes. Aloe vera (syn.: Aloe barbadensis Miller) was a perennial succulent plant belonging to the Aloeaceae family (subfamily of the Asphodelaceae). It has been reported that Aloe vera extracts were useful in the treatment of wound and burn healing, minor skin infections, sebaceous cyst, diabetes, and elevated blood lipids in humans. Recent studies have shown that treatment with either Aloe vera crude gel or its extracts, such as acemannan, β-sitosterol, and others, resulted in faster healing of wounds by stimulating fibroblast proliferation, collagen deposition, angiogenesis, and production of growth factors. Ionizing radiation technology has been developed to improve our daily life such as cancer therapy and sterilizing tool due to its unique feature that could be penetrated biomaterials leading to alter their own physical properties. More recently, many studies have attempted to apply the radiation technology to enhance their biological activities. At present, however, very little was known about whether naturally-occurring phenolic compounds of ethanolic aloe gel extracts that were altered their biological activities by ionizing radiation to serve as antioxidant in the body to reduce ROS produced by the stresses. The purpose of the current study was to investigate the influence of gamma irradiation on antioxidant activity of Aloe vera extracts, and open insight new possibilities that gamma ray could be a powerful tool for improving its own biological activities

  20. Strong enhancement of antioxidant activity of Aloe vera extracts by gamma irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Mi; Bai, Hyoung Woo; Lee, Seung Sik; Hong, Sung Hyun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Cho, Jae Young; Chung, Byung Yeoup [Chonbuk National University, Jeonju (Korea, Republic of)

    2011-10-15

    The World Health Organization (WHO) has estimated that approximately 80% of individuals rely on traditional medicines. Among over 400 Aloe species, Aloe vera was the most accepted species for various medical, cosmetic and neutraceutical purposes. Aloe vera (syn.: Aloe barbadensis Miller) was a perennial succulent plant belonging to the Aloeaceae family (subfamily of the Asphodelaceae). It has been reported that Aloe vera extracts were useful in the treatment of wound and burn healing, minor skin infections, sebaceous cyst, diabetes, and elevated blood lipids in humans. Recent studies have shown that treatment with either Aloe vera crude gel or its extracts, such as acemannan, {beta}-sitosterol, and others, resulted in faster healing of wounds by stimulating fibroblast proliferation, collagen deposition, angiogenesis, and production of growth factors. Ionizing radiation technology has been developed to improve our daily life such as cancer therapy and sterilizing tool due to its unique feature that could be penetrated biomaterials leading to alter their own physical properties. More recently, many studies have attempted to apply the radiation technology to enhance their biological activities. At present, however, very little was known about whether naturally-occurring phenolic compounds of ethanolic aloe gel extracts that were altered their biological activities by ionizing radiation to serve as antioxidant in the body to reduce ROS produced by the stresses. The purpose of the current study was to investigate the influence of gamma irradiation on antioxidant activity of Aloe vera extracts, and open insight new possibilities that gamma ray could be a powerful tool for improving its own biological activities

  1. Aloe vera: A short review

    Directory of Open Access Journals (Sweden)

    Surjushe Amar

    2008-01-01

    Full Text Available Aloe vera is a natural product that is now a day frequently used in the field of cosmetology. Though there are various indications for its use, controlled trials are needed to determine its real efficacy. The aloe vera plant, its properties, mechanism of action and clinical uses are briefly reviewed in this article.

  2. Aloe vera: Plant of Immortality

    Directory of Open Access Journals (Sweden)

    Sikarwar Mukesh. S.

    2010-02-01

    Full Text Available The Egyptians called Aloe the “Plant of Immortality” because it can live and even bloom without soil. Aloe has been used medicinally since at least the first century C.E. and continues to be used extensively worldwide.

  3. ALOE VERA: A SHORT REVIEW

    OpenAIRE

    Surjushe Amar; Vasani Resham; Saple D

    2008-01-01

    Aloe vera is a natural product that is now a day frequently used in the field of cosmetology. Though there are various indications for its use, controlled trials are needed to determine its real efficacy. The aloe vera plant, its properties, mechanism of action and clinical uses are briefly reviewed in this article.

  4. Transdermal penetration enhancement and clinical efficacy of Aloe marlothii and Aloe ferox compared to Aloe vera / Lizelle Trifena Fox

    OpenAIRE

    Fox, Lizelle Trifena

    2014-01-01

    Extensive research has already been performed on Aloe vera therefore it is important that researchers include other aloe species, such as Aloe marlothii and Aloe ferox, in studies involving aloe plant materials (Loots et al., 2007:6891). The use of natural products has regained popularity and in recent years the demand for alternative medication has risen considerably (Walji & Wiktorowicz, 2013:86). The hydration state of the human skin is fundamental for its normal functioning...

  5. 增强UV-B辐射对3种芦荟蒽醌类物质含量的影响%Effects of Enhanced UV-B Radiation on Anthraquinones Content of 3 Species of Aloe

    Institute of Scientific and Technical Information of China (English)

    王红星; 胡春红; 李景原

    2011-01-01

    以中华芦荟、库拉索芦荟和木立芦荟为试验材料,采用HPLC技术,研究了增强UV-B辐射对3种芦荟叶片中主要药用成分总蒽醌、芦荟素和芦荟大黄素含量的影响.结果显示:增强UV-B辐射20 d,每天处理6 h,库拉索芦荟和木立芦荟叶中总蒽醌、芦荟素、芦荟大黄素的含量增加,叶提取物中出峰数量增多,总峰面积增大;而中华芦荟中蒽醌类物质含量显著降低,叶提取物中出峰数量减少,总峰面积减少.研究表明,增强UV-B辐射能刺激库拉索芦荟和木立芦荟叶片中蒽醌类物质的积累和新物质的合成,而不利于中华芦荟蒽醌类物质的积累.%Effects of enhanced UV-B radiation on anthraquinones,aloin and aloe-emondin contents of 3 species of Aloe were studied by High Performance Liquid Chromatography(HPLC).The results indicated that twenty days of enhanced UV-B radiation (daily 6 h) could increase total anthraquinone,aloin,aloe-emodin contents in Aloe barbadensis and Aloe arborescens leaves.In addition,the number of peaks,the total peak area increased in A.barbadensis and A.arborescens leaf extracts.However, the total anthraquinone, aloin,aloe-emodin contents, the number of peaks,the total peak area lowered significantly under the UV-B radiation in Aloe vera var.chinensis.This result shows that the accumulation of anthraquinone in A.barbadensis and A.arborescens leaves can be promoted by UV-B radiation but not conducive to A.vera var.chinensis.

  6. Effect of pomegranate and aloe vera extract on streptococcus mutans: An in vitro study

    Directory of Open Access Journals (Sweden)

    Priya Subramaniam

    2012-01-01

    Full Text Available Introduction: The aim of the present in vitro study was to evaluate and compare the antibacterial effect of pomegranate and aloe vera extracts on Streptococcus mutans. Materials and Methods: Hydroalcoholic extracts of pulp from both Punica granatum (pomegranate and Aloe barbadensis miller (aloe vera were prepared to concentrations of 5, 25, 50 and 100%. Pure sorbitol powder dissolved in distilled water was taken as the negative control. Streptococcus mutans (S mutans was isolated from saliva by inoculation on to Mitus Salivarius Bacitracin (MSB agar, which was then streaked onto agar plates containing Brain Heart Infusion. In each petridish, wells were prepared and using a sterile micropipette, 125μl of the specific concentration of the extract (pomegranate/ aloe vera/ sorbitol was deposited in each well. This was done in triplicate for each concentration of the extracts. The effect of different concentrations of the extracts on S mutans was observed and the data was subjected to statistical analysis. Results: Pomegranate extract showed significantly higher inhibitory effect on S mutans at all concentrations (P≤0.05. On comparison of all three extracts at different concentrations, a significant difference (P≤0.05 was observed only at 50 and 100% concentrations. The inhibitory effect of pomegranate extract was significantly different when compared to aloe vera and sorbitol extracts. (P≤0.01. Discussion: Pomegranate extract has a significant antibacterial effect on S mutans at all concentrations.

  7. Bob miller's math for the GMAT

    CERN Document Server

    Miller, Bob

    2012-01-01

    Maximize Your GMAT Math Score with Bob Miller! REA's updated second edition of Bob Miller's Math for the GMAT is a must for anyone taking the GMAT. Bob Miller has taught math to thousands of students at all educational levels for 30 years. His proven teaching methods will help you master the math section of the GMAT and boost your score! Written in a lively and unique format, Bob Miller's Math for the GMAT prepares GMAT-takers with everything they need to know. Unlike some dull test preps that merely present the material, Bob actually teaches and explains math concepts and ideas. His no-no

  8. Antifungal and cytotoxic activity of withanolides from Acnistus arborescens.

    Science.gov (United States)

    Roumy, Vincent; Biabiany, Murielle; Hennebelle, Thierry; Aliouat, El Moukhtar; Pottier, Muriel; Joseph, Henry; Joha, Sami; Quesnel, Bruno; Alkhatib, Racha; Sahpaz, Sevser; Bailleul, François

    2010-07-23

    Three compounds were isolated from Acnistus arborescens, a tree commonly used in South and Central America in traditional medicine against several infectious diseases, some of which are caused by fungi. Bioassay-guided fractionation of a MeOH extract of leaves, based on its anti-Pneumocystis carinii activity, led to the isolation of compounds 1-3. Mono- and bidimensional NMR analyses enabled identification of two new withanolides, (20R,22R)-5beta,6beta-epoxy-4beta,12beta,20-trihydroxy-1-oxowith-2-en-24-enolide (1) and (20R,22R)-16beta-acetoxy-3beta,4beta;5beta,6beta-diepoxy-12beta,20-dihydroxy-1-oxowith-24-enolide (2), and withanolide D (3). Antifungal activity on 13 fungi responsible for human infections (five dermatophytes, one nondermatophyte mold, six yeasts, and Pneumocystis carinii) was examined. Cytotoxicity of these compounds was also evaluated in vitro. PMID:20590148

  9. Lipoma arborescens arising in the extra-articular bursa of the knee joint

    Directory of Open Access Journals (Sweden)

    Minami Shinji

    2016-01-01

    Full Text Available Lipoma arborescens arising in the extra-articular bursa of the knee joint is extremely rare. We describe an 11-year-old boy who complained of a gradual swelling mass of the lateral knee joint. Magnetic resonance imaging (MRI showed a high signal intensity tumor on T1- and T2-weighted images with a thickened septa and nodular lesion that showed low signal intensity. The radiologist suggested the possible differential diagnosis of well-differentiated liposarcoma. At operation, the tumor was found under the iliotibial tract and was not in contact with the knee joint. Histopathologically, this lesion was diagnosed as lipoma arborescens arising in the extra-articular bursa of the knee joint. On MRI, the appearance of lipoma arborescens arising in the extra-articular bursa of the knee joint differed from that of conventional intra-articular lipoma arborescens. In this report, we describe a case of extra-articular lipoma arborescens of the knee joint bursa and discuss the diagnosis and etiology.

  10. Lipoma arborescens arising in the extra-articular bursa of the knee joint.

    Science.gov (United States)

    Minami, Shinji; Miyake, Yusuke; Kinoshita, Hirofumi

    2016-01-01

    Lipoma arborescens arising in the extra-articular bursa of the knee joint is extremely rare. We describe an 11-year-old boy who complained of a gradual swelling mass of the lateral knee joint. Magnetic resonance imaging (MRI) showed a high signal intensity tumor on T1- and T2-weighted images with a thickened septa and nodular lesion that showed low signal intensity. The radiologist suggested the possible differential diagnosis of well-differentiated liposarcoma. At operation, the tumor was found under the iliotibial tract and was not in contact with the knee joint. Histopathologically, this lesion was diagnosed as lipoma arborescens arising in the extra-articular bursa of the knee joint. On MRI, the appearance of lipoma arborescens arising in the extra-articular bursa of the knee joint differed from that of conventional intra-articular lipoma arborescens. In this report, we describe a case of extra-articular lipoma arborescens of the knee joint bursa and discuss the diagnosis and etiology. PMID:27382924

  11. A critical evaluation of the Miller and Miller similar media theory for application to natural soils

    Science.gov (United States)

    Sadeghi, Morteza; Ghahraman, Bijan; Warrick, Arthur W.; Tuller, Markus; Jones, Scott B.

    2016-05-01

    The Miller-Miller similar media theory is widely applied to characterize the spatial variability of soil hydraulic properties. For a group of soils, a distinct scaling factor is commonly assigned to each individual soil to coalesce the soil water characteristic and hydraulic conductivity functions to single curves. It is generally assumed that the Miller-Miller theory is valid as long as soils are "similar" either with regard to their microscopic pore space geometry or the closely related macroscopic soil hydraulic functions. In this paper, it is illustrated that similarity is not the sole required condition for validity of the Miller-Miller theory. In addition, the interrelation between the soil water characteristic and the hydraulic conductivity functions considered for scaling need to be comparable. The interrelation is dependent not only on the pore space geometry, but also on solid-liquid interactions. Hence similar interrelation cannot be concluded from similarity of microscopic pore space geometry. A dimensionless parameter termed the "joint scaling factor" was defined and applied to evaluate the soundness of the interrelation condition for 26 soils from the UNSODA database that were grouped into six classes of similar soils. Obtained results clearly reveal the crucial importance of the interrelation condition for the Miller-Miller scaling theory, which has been hidden behind the "similarity" requirement, and contradict the general belief that Miller-Miller scaling is valid as long as soils are "similar."

  12. Modulation of radiation injuries in rats receiving multiple doses of Aloe Vera

    International Nuclear Information System (INIS)

    This study has been performed to examine the efficacy of Aloe vera juice (Aloe barbadensis Miller) against radiation injuries of 7 Gy whole body gamma irradiation (single dose). Inductions of lipid peroxidation (thiobarbituric acid reactive substances, (TBARS)) of biomembranes lipids as well as the subsequent changes in the activities of subcellular organelle marker enzymes were discussed. Activities of glutamate dehydrogenase (GDH), acid phosphatase and glucose-6-phosphatase (marker enzymes of mitochondria, lysosome and microsomes, respectively) were estimated. The activities of these enzymes were also measured in cytosol. Subcellular fractionation's were performed in liver, heart and spleen tissues. Aloe vera was supplemented daily to rats (0.25 ml/kg body wt/day) by gavage, 5 days before irradiation and treatment was extended for 10 days post irradiation. Experimental investigations were performed on the 3rd and 10th day after exposure to radiation. The results obtained indicated that, Aloe vera administration has significantly minimized the radiation-induced increase in the amount of TBARS in different cell fractions as compared with control rats. Significant amelioration in the activities of organelles marker enzymes GDH, acid phosphatase and glucose-6-phosphatase was observed from 3rd up to 10th days for the 3 tissues. The results also detected improvement in cytosolic enzyme activities due to Aloe vera intake. It could be suggested that the diverse active constituents of Aloe vera play a significant role in decreasing the peroxidation of subcellular membrane lipids induced by radiation exposure, prevent diffusion of organelle enzymes to cytosol and consequently salvage the integrity of living cell

  13. A chemotaxonomic and morphological appraisal of Aloe series Purpurascentes, Aloe section Anguialoe and their hybrid, Aloe broomii.

    Science.gov (United States)

    Viljoen, A M.; van Wyk, B -E.

    2001-06-01

    Evidence is presented to suggest the hybrid origin of Aloe broomii, with the one putative parent belonging to Aloe series Purpurascentes and the other a member of Aloe series Anguialoe. A chemotaxonomic and morphological assessment is presented for both infrageneric groups and their hypothesised hybrid. Four of the species belonging to the series Purpurascentes display a characteristic leaf exudate profile containing the chemotaxonomic marker microstigmin. Aloe gariepensis and A. succotrina lack the diagnostic leaf exudate compounds. The distinct morphological apomorphies for Aloe section Anguialoe are supported on the chemical level reinforcing the monophyly of this group. PMID:11336811

  14. Lipoma arborescens: caso raro de ruptura do manguito rotador associado à presença de lipoma arborescens na bursa subacromial-subdeltoidea e glenoumeral Lipoma arborescens: rare case of rotator cuff tear associated with the presence of lipoma arborescens in the subacromial-subdeltoid and glenohumeral bursa

    Directory of Open Access Journals (Sweden)

    Eduardo Benegas

    2012-01-01

    Full Text Available Lipoma arborescens é uma condição rara de moléstia intra-articular, usualmente monoarticular, caracterizada por extensa proliferação dos vilos sinoviais e hiperplasia da gordura subsinovial. O tecido sinovial é progressivamente substituído por células maduras de gordura na membrana sinovial. O presente trabalho é o relato de caso de uma condição rara de lipoma arborescens tanto intra-articular (glenoumeral como da bursa subacromial-subdeltoide além de ruptura do tendão do supraespinhoso. As apresentações clínicas, histológicas e radiográficas assim como o tratamento são discutidos no presente estudo. A apresentação do caso contempla também a avaliação radiográfica, ressonância magnética e exame patológico. Apesar do lipoma arborescens ser uma condição rara, tal hipótese deve ser considerada frente a um caso com hiperproliferação sinovial e lipossubstituição da sinovial.Lipoma arborescens is a rare intra-articular disease that is usually monoarticular and is characterized by extensive proliferation of the synovial villi and hyperplasia of the subsynovial fat. The synovial tissue is progressively replaced by mature fat cells in the synovial membrane. The present study reports a case of a rare condition of lipoma arborescens that was simultaneously intra-articular (glenohumeral joint and in the subacromial-subdeltoid bursa, in association with a torn supraspinatus tendon. The clinical, histological and radiographic presentations and treatment are discussed here. The description of this case includes radiographic and magnetic resonance evaluations and pathological examination. Although lipoma arborescens is a rare condition, it should be taken into consideration in cases presenting synovial hyperproliferation and synovial fat replacement.

  15. Genetics Home Reference: Miller-Dieker syndrome

    Science.gov (United States)

    ... allows the abdominal organs to protrude through the navel. People with Miller-Dieker syndrome may also have ... Disorders and Stroke: Seizures and Epilepsy: Hope Through Research Educational Resources (4 links) Cleveland Clinic: Lissencephaly Disease ...

  16. David Miller on Immigration Policy and Nationality

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2007-01-01

    David Miller's recent statement of the case for restrictive immigration policies can plausibly be construed as an application of a ‘liberal nationalist' position. The paper first addresses Miller's critique of distributive justice arguments for open borders, which relies on nationality as determi......David Miller's recent statement of the case for restrictive immigration policies can plausibly be construed as an application of a ‘liberal nationalist' position. The paper first addresses Miller's critique of distributive justice arguments for open borders, which relies on nationality......, as a context of choice, and as an object of self-determination. The paper assesses the plausibility of Miller's nationalist arguments, and concludes that they are either implausible or peculiarly weak compared to other considerations in favour of restrictions. Several of the arguments may alternatively...... be construed as non-nationalist, and it is argued that Miller's arguments are more plausible when considered as such. The broader implication is that, even if the concern with nationality is relevant and legitimate in other areas of politics, it is, perhaps surprisingly, either inappropriate or insignificant...

  17. Semen characteristics and sperm morphological studies of the West African Dwarf Buck treated with Aloe vera gel extract

    Directory of Open Access Journals (Sweden)

    Oyeyemi Matthew Olugbenga

    2011-01-01

    Full Text Available Background: Aloe vera (Aloe barbadensis miller is an evergreen perennial plant widely used in modern herbal practice and is often available in proprietary herbal preparations.Objective: This study was designed to investigate the semen picture and spermatozoa morphology of West African Dwarf (WAD bucks treated with Aloe vera extract.Materials and Methods: Twelve sexually matured WAD bucks, weighing between 11 and 15 kg, were used for the study. The bucks were first used as control (pre-treatment and later as two groups of six animals each. The first six bucks received 10 mls of the 3% extract while the other six received 10 mls of the 4% of the extract for a 7 day period. Semen was collected from both the 3 and 4% extract treated bucks for the control (pre-treatment, on days eight (first week post-treatment and fifteen (second week post-treatment in each case using the electroejaculation method. The spermiogram of the bucks were investigated using standard procedures. Data obtained were analyzed using two way ANOVA and significance reported at p<0.05.Results: The continuous administration of Aloe vera extract significantly (p<0.05 reduced sperm concentration, motility and percentage livability and resulted in increased sperm abnormalities in the WAD buck.Conclusion: Aloe vera adversely affected the spermiogram of bucks. The plant can reduce fertility in male animals and is therefore not recommended for medicinal purpose in male animals especially those used for breeding.

  18. George A. Miller (1920-2012).

    Science.gov (United States)

    Pinker, Steven

    2013-09-01

    Presents an obituary for George A. Miller (1920-2012). Miller ranks among the most important psychologists of the 20th century. In addition to writing one of the best known papers in the history of psychology ("The Magical Number Seven, Plus or Minus Two: Some Limits on Our Capacity for Processing Information," published in Psychological Review in 1956), Miller also fomented the cognitive revolution, invented psycholinguistics and cognitive psychology, imported powerful ideas from the theories of information, communication, grammar, semantics, and artificial intelligence, and left us a sparkling oeuvre that proves that a rigorous scientist needn't write in soggy prose. Honors rained down on Miller. APA gave him the Award for Distinguished Scientific Contributions (1963), the American Psychological Foundation Gold Medal Award for Life Achievement in Psychological Science (1990), the William James Book Award (1992, for The Science of Words), and the Award for Lifetime Contributions to Psychology (2003), and named a prize after him, as did the Cognitive Neuroscience Society. Miller was also honored by the Association for Psychological Science and the American Speech and Hearing Association. In 2000, he won the John P. McGovern Award in the Behavioral Sciences from the American Association for the Advancement of Science, and in 1991, the National Medal of Science, the country's highest scientific honor.

  19. Benefits of Aloe vera in dentistry

    OpenAIRE

    Mangaiyarkarasi, S. P.; Manigandan, T.; Elumalai, M.; Cholan, Priyanka K.; Roopam Pal Kaur

    2015-01-01

    Aloe vera (Aloe barbadensis) is a plant that belongs to Liliaceae family. The name Aloe derives from the Arabic word "Alloeh" meaning shining bitter substance while "vera" in Latin means true. It contains various minerals and vitamins. It has got various properties such as immunomodulatory, antiviral and antiinflammatory in nature. A. vera can play a significant role in dentistry in treatment of lichen planus, oral submucous fibrosis, recurrent aphthous stomatitis, alveolar osteitis, periodon...

  20. Daya Hambat Ekstrak Aloe Vera terhadap pertumbuhan Staphylococcus Aureus

    OpenAIRE

    Rahmat, drg.Sp,Pros

    2011-01-01

    Dari hasil penelitian , maka dapat disimpulkan bahwa ekstrak Aloe Vera dapat menghambat pertumbuhan bakteri Stafhylococcus aureus, dan kadar hambat minimal ekstrak Aloe Vera adalah pada konsentrasi 25%.

  1. The cultural conflict in Daisy Miller

    Institute of Scientific and Technical Information of China (English)

    岳娜

    2014-01-01

    This thesis, taking Daisy Miller as an example, concentrates on the cultural conflict between the new and old continents reflected in this work, presenting the conflict between two cultures, that is, American innocence and European sophistication from the perspective of settings.

  2. Fighting desires: Henry Miller's Queer Tropic.

    Science.gov (United States)

    Hardin, Michael

    2002-01-01

    "Fighting Desires: Henry Miller's Queer Tropic" is an investigation of Tropic of Cancer that investigates the deeply repressed homoerotic desire that periodically surfaces. This reading is dependent upon an interpretation of Eve Sedgwick that proposes male sexuality as a continuum. By looking at the nature of the male-male relationships, as well as the lack of emotion and presence in the male-female relationships, I will show that the most intimate relationships are between men, and that these relationships are expressed through the telling of stories about (heterosexual) sex; this is the function of women within the novel: one has sex with a woman, not for the pleasure that the act brings, but for the pleasure that the recounting of the story to other men brings. Furthermore, I will look at Miller's use of puns within the novel and how they also contribute to a homoerotic reading. None of this is to argue that Miller was not homophobic and sexist--Miller very clearly was--the purpose of this essay is to show the complex nature of sexuality, even within a protagonist who asserts a very defined heterosexuality.

  3. Karyosome type study of four species of Aloe%芦荟属四种植物染色体核型研究

    Institute of Scientific and Technical Information of China (English)

    纪春艳; 马玉心; 崔大练

    2002-01-01

    对中国芦荟(Aloe vera var.chinensis)、木锉芦荟(A.humilis)、大蚣掌(A.arborescens)、开普芦荟(A.felox)4种芦荟进行了染色体观察与核型分析,4种芦荟染色体数目均为2n=14.染色体核型公式分别为K(2n)=2x=14=8st+6sm,K(2n)=2x=14=6st+8sm,K(2n)=2x=14=6st+2t+2m+4sm,K(2n)=2x=14=10st+4sm,根据核型研究,初步确定芦荟属的染色体基数为X=7.

  4. James M. Decker, Indrek Manniste, eds. Henry Miller: New Perspectives.

    OpenAIRE

    Cowe, Jennifer

    2016-01-01

    Henry Miller continues to be a writer who causes much consternation amongst readers and critics alike. Often characterised as everything for a pornographer, misogynist, counter-cultural hero to sexual libertine, Miller has frequently been pigeonholed by critics to fit their agenda. This, along with changing sensibilities within literary criticism has led to a relegation of Miller to the minor leagues of research and academia. Thus, this edition of essays by many of today’s leading Miller scho...

  5. Antidiabetic effects of Aloe ferox and Aloe greatheadii var. davyana leaf gel extracts in a low-dose streptozotocin diabetes rat model

    Directory of Open Access Journals (Sweden)

    Lisa Botes

    2011-07-01

    Full Text Available The medicinal use and commercialisation of the plants Aloe ferox and Aloe greatheadii are primarily based on research done on Aloe vera and Aloe arborescens. Consequently, in this study we investigated the possible antidiabetic effects of ethanol extracts of A. ferox and A. greatheadii var. davyana leaf gel in a streptozotocin (STZ-induced type 2 diabetes rat model. Fifty male Wistar rats, weighing 200 g – 250 g, were randomly divided into five groups of n = 10: normal control rats, diabetic control rats, diabetic rats receiving A. ferox leaf gel extract (300 mg/kg, diabetic rats receiving A. greatheadii leaf gel extract (300 mg/kg, and diabetic rats receiving glibenclamide (600 μg/kg. Diabetes was induced by a single intraperitoneal injection of STZ (40 mg/kg. Rats were sacrificed 5 weeks after injection, following a 12-hour fast, and blood and tissue samples were collected. Compared to the normal control group, STZ significantly increased relative liver and kidney weights, end-point plasma glucose, fructosamine, oxidative stress, liver enzymes, total cholesterol (TC, triglycerides, very low density lipoprotein-cholesterol and TC: high density lipoprotein-cholesterol (HDL-C values and reduced serum insulin levels. Treatment with A. greatheadii moderately increased serum insulin and HDL-C levels and moderately reduced end-point plasma glucose and liver alkaline phosphatase (ALP and significantly decreased TC:HDL-C ratios. A. ferox supplementation similarly resulted in moderately increased serum insulin, accompanied by slight corrections in ALP and HDL-C, without any change to end-point plasma glucose values. A. greatheadii and, to a lesser extent, A. ferox, resulted in a clinically relevant improved diabetic state (indicated by moderate to high effect sizes, suggesting that these Aloe species may show promise

  6. Chiral separation of hesperidin and naringin and its analysis in a butanol extract of Launeae arborescens.

    Science.gov (United States)

    Belboukhari, Nasser; Cheriti, Abdelkrim; Roussel, Christian; Vanthuyne, Nicolas

    2010-04-01

    Two flavanone glycosides were isolated from the aerial part of Launeae arborescens (Asteraceae), which were identified as hesperidin and naringin. They are the most abundant flavonoids in the edible parts of many species of citrus fruits. In this study, we were interested in the chiral separation and determination of the diastereomerisation barriers of hesperidin and naringin by HPLC methods. The chiral separation HPLC screening of diastereomers of hesperidin and naringin by HPLC methods was accomplished in the normal-phase mode using 11 chiral stationary phases and various n-hexane/alcohol mobile phases. The rate constants and activation energy of diastereomerisation (DeltaG#) of flavanones, naringin and hesperidin were determined, respectively, on Chiralpak IC and Chiralpak IA. The analysis of flavanones isolated in butanol extracts of Launeae arborescens were confirmed by HPLC on Chiralpak IC. PMID:20401799

  7. Lipoma Arborescens: Review of an Uncommon Cause for Swelling of the Knee

    Directory of Open Access Journals (Sweden)

    M. De Vleeschhouwer

    2016-01-01

    Full Text Available Lipoma arborescens is a rare cause of chronic monoarticular arthritis, with only a few cases reported in the literature. It is most commonly seen in the knee, but cases in other joints such as the wrist, shoulder, and elbow have also been described. It is a benign condition, in which the subsynovial tissue is replaced diffusely by mature fat cells. We describe a case involving the knee and discuss the symptoms, diagnosis, and treatment.

  8. Prebiotic Soup: Revisiting the Miller Experiment

    Science.gov (United States)

    Bada, Jeffrey L.; Lazcano, Antonio

    2003-01-01

    Isn't life wonderful? sang Alma Cogan and Les Howard in their almost forgotten 1953 hit. That same year, Stanley L. Miller raised the hopes of understanding the origin of life when on 15 May, Science published his paper on the synthesis of amino acids under conditions that simulated primitive Earth's atmosphere. Miller had applied an electric discharge to a mixture of CH4, NH3, H2O, and H2 - believed at the time to be the atmospheric composition of early Earth. Surprisingly, the products were not a random mixture of organic molecules. but rather a relatively small number of biochemically significant compounds such as amino acids, hydroxy acids, and urea. With the publication of these dramatic results, the modern era in the study of the origin of life began.

  9. Prebiotic Soup-Revisiting the Miller Experiment

    Science.gov (United States)

    Bada, Jeffrey L.; Lazcano, Antonio

    2003-01-01

    'Isn't life wonderful?' sang Alma Cogan and Les Howard in their almost forgotten 1953 hit. That same year, Stanley L. Miller raised the hopes of understanding the origin of life when on 15 May, Science published his paper on the synthesis of amino acids under conditions that simulated primitive Earth's atmosphere. Miller had applied an electric discharge to a mixture of CH4, NH3, H2O, and H2 - believed at the time to be the atmospheric composition of early Earth. Surprisingly, the products were not a random mixture of organic molecules, but rather a relatively small number of biochemically significant compounds such as amino acids, hydroxy acids, and urea. With the publication of these dramatic results, the modem era in the study of the origin of life began.

  10. The origin and predominance of Aloe vera

    OpenAIRE

    Walker, Colin

    2015-01-01

    Aloe vera is undoubtedly the best known succulent because it is the basis of a multi-billion dollar global cosmetics and toiletries industries. This article reviews its origin based on the latest evolutionary tree.

  11. Beyond Sectarianism?:On David Miller's Theory of Human Rights

    OpenAIRE

    Oberman, Kieran

    2013-01-01

    In his most recent book, National Responsibility and Global Justice, David Miller presents an account of human rights grounded on the idea of basic human needs. Miller argues that his account can overcome what he regards as a central problem for human rights theory: the need to provide a 'non-sectarian' justification for human rights, one that does not rely on reasons that people from non-liberal societies should find objectionable. The list of human rights that Miller's account generates is,...

  12. Aloe succotrina (Asphodelaceae)

    OpenAIRE

    Walker, C. C.; R. R. Klopper; G. F. Smith; Condy, Gillian

    2015-01-01

    Aloe succotrina has a very long and complex taxonomic and nomenclatural history with wrong synonymy that is rivalled by few other aloes. This is mostly due to early authors wrongly assuming that this plant is from the Island of Socotra (Reynolds 1950). It has been in cultivation in Europe for over three hundred years, so consequently it is rather surprising that this iconic fynbos species has not featured in this journal until now.

  13. Recurrent Miller fisher syndrome : a case report.

    Directory of Open Access Journals (Sweden)

    Sitajayalakshmi S

    2002-07-01

    Full Text Available Miller fisher syndrome (MFS is a variant of Guillain-Barre syndrome characterized by the triad of ophthalmoplegia, ataxia and areflexia. Recurrences are exceptional with MFS. A case with two episodes of MFS within four years is reported. He presented with findings of ophthalmoplegia, ataxia, areflexia, and oropharyngeal weakness and mild distal sensory impairment during both episodes. Electrophysiological findings showed reduced compound muscle action potentials and sensory nerve action potentials with no evidence of conduction blocks. Nerve biopsy showed segmental demyelination. MRI of brain was normal. He responded well to immunoglobulins during both episodes suggesting that immunomodulating drugs have a role in the treatment of MFS.

  14. The Cultural Conflict in Daisy Miller

    Institute of Scientific and Technical Information of China (English)

    刘丹

    2015-01-01

    Henry James is one of the greatest novelists and literary theoretician, who enjoys great reputation in English literary world, often referred to as the pioneer of modern English novels and an “international theme",that is, the transatlantic intercourse unauthorized ambassador of culture of American and European society most of his fictional works, he dealt with the culture. This thesis, taking Daisy Miller as an example, will mainly focus on the cultural conflict between two cultures, that is, American innocence and European sophistication.

  15. Evolutionary history and leaf succulence as explanations for medicinal use in aloes and the global popularity of Aloe vera

    DEFF Research Database (Denmark)

    Grace, Olwen Megan; Buerki, Sven; Symonds, Matthew RE;

    2015-01-01

    Background: Aloe vera supports a substantial global trade yet its wild origins, and explanations for its popularity over 500 related Aloe species in one of the world’s largest succulent groups, have remained uncertain. We developed an explicit phylogenetic framework to explore links between...... the rich traditions of medicinal use and leaf succulence in aloes. Results: The phylogenetic hypothesis clarifies the origins of Aloe vera to the Arabian Peninsula at the northernmost limits of the range for aloes. The genus Aloe originated in southern Africa ~16 million years ago and underwent two major...... succulence among aloes has yielded new explanations for the extraordinary market dominance of Aloe vera. The industry preference for Aloe vera appears to be due to its proximity to important historic trade routes, and early introduction to trade and cultivation. Well-developed succulent leaf mesophyll tissue...

  16. 不同芦荟品种主要成分及抗菌作用的比较研究%Comparison on Main Component and Antibiotic Action of Different Aloe

    Institute of Scientific and Technical Information of China (English)

    都兴范; 王关林

    2004-01-01

    芦荟系百合科多年生肉质常绿植物,自古以来就是我国一种重要的药材。具有抗肿瘤、杀菌、美容和保健等功效。但由于目前分布于世界的芦荟属植物多达500余种,而且各品种间的药用成分存在着一定的差异。为此,我们对目前国内市场应用较多的3种芦荟,即木立芦荟(Aloe arborescens)、库拉索芦荟(Aloe vera Linn)和开普芦荟(Aloe africana)的主要成分含量进行了研究比较,为其今后应用提供依据。

  17. Entrevista con Jacques-Alain Miller.

    Directory of Open Access Journals (Sweden)

    Francisco Estévez González

    1987-01-01

    Full Text Available Jacques-Alain MILLER es psicoanalista, editor -uno de cuyos principales cometidos consiste en establecer los textos y la publicación de los Seminarios de Jacques LACAN, tal como le encargó el propio maestro escritor, prestigioso conferenciante y profesor especializado en los fundamentos del psicoanálisis. En la actualidad dirige el Departamento de Psicoanálisis de la Universidad de París VIII. Es miembro del Consejo de la Escuela de la Causa Freudiana, editor de las publicaciones del Campo Freudiano y director de la revista Ornicar, una de las más importantes publicaciones psicoanalíticas en el panorama internacional. Está casado con Judith MILLER -hija de LACAN-, presidenta de la Fundación del Campo Freudiano, con la que tiene dos hijos. Ha visitado España en numerosas ocasiones, pronunciando conferencias, dictando seminarios e impulsando la articulación de grupos de estudio psicoanalíticos en diversas ciudades. Es asesor editorial de la revista «El Analiticón», publicación del Campo Freudiano en España.

  18. Cytotoxic derivatives of withanolides isolated from the leaves of Acnistus arborescens; Derivados citotoxicos de vitanolidos isolados das folhas de Acnistus arborescens

    Energy Technology Data Exchange (ETDEWEB)

    Minguzzi, Sandro, E-mail: sming@uems.b [Universidade Estadual de Mato Grosso do Sul, Navirai, MS (Brazil). Curso de Quimica; Barata, Lauro E.S. [Universidade Estadual de Campinas (IQ/UNICAMP), SP (Brazil). Inst. de Quimica; Cordell, Geoffrey A. [Natural Products Inc., Evanston, IL (United States)

    2011-07-01

    In view of anticancer activity of 7 beta-acetoxywithanolide D (2) and 7beta-16beta-diacetoxywithonide D (3), isolated from the leaves of Acnistus arborescens (Solanaceae), five withanolide derivatives were obtained and their structures were determined by NMR, MS and IV data analysis. The in vitro anticancer activity of these derivatives was evaluated in a panel of cancer cell lines: human breast (BC-1), human lung (Lu1), human colon (Col2) and human oral epidermoid carcinoma (KB). Compounds 2a (acetylation of 2), 3b (oxidation of 3) and 2c (hydrogenation of 2) exhibited the highest anticancer activity against human lung cancer cells, with ED{sub 50} values of 0.19, 0.25 and 0.63 mug/mL, respectively. (author)

  19. Influence of lavender essential oil and aloe on main flora of facial acne%薰衣草精油和芦荟对痤疮面部主要菌群的影响

    Institute of Scientific and Technical Information of China (English)

    张美娇; 韩怡雪; 付洋; 冯媛; 吴大畅

    2013-01-01

    Objective To provide theoretical proofs for facial acne treatment by observing the influence of lavender essential oil and aqueous extract of aloe on main flora of facial acne (Propionibacterium acnes and Staphylococcus epidermidis) in vitro.Methods Serial dilution method was adopted to dilute lavender essential oil and aquedous extract of aloe.Paper disc method was performed to observe the effects of different concentrations of lavender essential oil and aquedous extract of aloe on facial flora.The effect of bacteriostasis was represented by the area of inhibition zone.Growth curve was plotted to detect the influence on bacteria growth.Results Lavender essential oil showed a stronger inhibitory activity against Propionibacterium acnes than Staphylococcus epidermidis (P < 0.05) ; Aloe vera and aloe arborescens mill did not seem to have inhibitory effect on Propionibacterium acnes (P > 0.05) ; Aloe vera had a weak inhibitory effect on Staphylococcus epidermidis (P < 0.05),while Aloe arborescens Mill showed a positive growth-promoting effect on Staphylococcus epidermidis.Conclusion The influences of lavender essential oil and aqueous extract of aloe on main flora of facial acne (Staphylococcus epidermidis and Propionibacterium acnes) are different.Application of lavender essential oil combined with aloe might help to improve facial acne symptoms through modulating facial microecological balance.%目的 体外观察薰衣草精油和芦荟水提物对痤疮患者面部痤疮丙酸杆菌和表皮葡萄球菌的作用,为改善面部痤疮治疗提供理论依据.方法 采用连续梯度稀释法稀释薰衣草精油及芦荟水提物,纸片法观察不同浓度的精油和芦荟水提物对面部正常菌群表皮葡萄球菌和痤疮主要致病菌痤疮丙酸杆菌的作用;通过抑菌环的大小反应抑菌作用强弱,测定生长曲线以观察对细菌生长繁殖的影响.结果 薰衣草精油对痤疮丙酸杆菌的抑菌作用明

  20. Lipoma arborescens associated with osseous/chondroid differentiation in subdeltoid bursa

    Directory of Open Access Journals (Sweden)

    Ryuh Sup Kim

    2013-01-01

    Full Text Available Lipoma arborescens (LA is a rare benign lesion of unknown etiology. It is characterized histologically by villous proliferation of the synovial membrane and diffuse replacement of the subsynovial tissue by mature fat cells. This condition affects the knee joint most commonly. Cases involving other locations including glenohumeral joint, [1] hip, [2] elbow, [3] hand [4] and ankle [5] have been rarely described. Involvement of the subdeltoid bursa has also been reported, but to date no case has described LA with osseous/chondroid differentiation of this bursa. Another significant finding in our case was the coexistence of LA with intermuscular lipoma, SLAP lesion and labral cyst.

  1. Processing of Aloe Vera Leaf Gel: A Review

    OpenAIRE

    Ramachandra, C. T.; P. S. Rao

    2008-01-01

    Proper scientific investigations on Aloe vera have gained more attention over the last decade due to its reputable, medicinal, pharmaceutical and food properties. Some publications have appeared in reputable scientific journals that have made appreciable contributions to the discovery of the functions and utilizations of Aloe vera lacking processing of leaf gel. Present processing techniques aims at producing best quality aloe products but end aloe products contain very little or virtually no...

  2. Artemisia arborescens Essential Oil Composition, Enantiomeric Distribution, and Antimicrobial Activity from Different Wild Populations from the Mediterranean Area.

    Science.gov (United States)

    Said, Mohammed El-Amin; Militello, Marcello; Saia, Sergio; Settanni, Luca; Aleo, Aurora; Mammina, Caterina; Bombarda, Isabelle; Vanloot, Pierre; Roussel, Christian; Dupuy, Nathalie

    2016-08-01

    Aerial parts of Artemisia arborescens were collected from different sites of the Mediterranean area (southwestern Algeria and southern Italy) and the chemical composition of their essential oil (EO) extracted by hydrodistillation was studied by both gas chromatography (GC) equipped with an enantioselective capillary column and GC/mass spectrometry (GC/MS). The EOs obtained were tested against several Listeria monocytogenes strains. Using GC and GC/MS, 41 compounds were identified, accounting for 96.0 - 98.8% of the total EO. All EOs showed a similar terpene profile, which was rich in chamazulene, β-thujone, and camphor. However, the concentration of such compounds varied among the EOs. A. arborescens EO inhibited up to 83.3% of the L. monocytogenes strains, but the inhibitory spectrum varied among the EOs, with those from Algeria showing a higher inhibition degree than the Italian EOs. Such effect likely depended on the ketone (β-thujone + camphor) content of the EO. The differences in the EO composition support the hypothesis that A. arborescens has at least two different chemotypes: a β-thujone and a chamazulene type. The EO inhibitory spectrum indicates the A. arborescens EO as a valuable option in the control of the food-borne pathogens. PMID:27447740

  3. Hypoglycemic and Hypolipidemic Effects of Aloe vera Extract Preparations: A Review.

    Science.gov (United States)

    Pothuraju, Ramesh; Sharma, Raj Kumar; Onteru, Suneel Kumar; Singh, Satvinder; Hussain, Shaik Abdul

    2016-02-01

    Obesity is considered to be an epidemic disease, and it is associated with several metabolic disorders. Pharmacological treatments currently available are not effective for prolonged treatment duration. So, people are looking toward new therapeutic approach such as herbal ingredients. Since ancient periods, different herbs have been used for remedy purposes such as anti-obesity, antidiabetes, and antiinflammatory. Among the several herbal ingredients, Aloe vera (Aloe barbadensis Miller) is widely used to curb the metabolic complications. Till date, reports are not available for the side effects of A. vera. Several researchers are used to different solvents such as aqueous solution, alcohol, ethanol, and chloroform for the A. vera extract preparations and studied their hypoglycemic and hypolipidemic effects in animal and human studies. Furthermore, little information was recorded with the active compounds extracted from the A. vera and their anti-obesity and antidiabetic effects in clinical studies. In this review, we made an attempt to compile all the available literature by using different search engines (PubMed, Scopus, and Google Scholar) on the A. vera extract preparations and the possible mechanism of action involved in carbohydrate and lipid metabolism.

  4. Hypoglycemic and Hypolipidemic Effects of Aloe vera Extract Preparations: A Review.

    Science.gov (United States)

    Pothuraju, Ramesh; Sharma, Raj Kumar; Onteru, Suneel Kumar; Singh, Satvinder; Hussain, Shaik Abdul

    2016-02-01

    Obesity is considered to be an epidemic disease, and it is associated with several metabolic disorders. Pharmacological treatments currently available are not effective for prolonged treatment duration. So, people are looking toward new therapeutic approach such as herbal ingredients. Since ancient periods, different herbs have been used for remedy purposes such as anti-obesity, antidiabetes, and antiinflammatory. Among the several herbal ingredients, Aloe vera (Aloe barbadensis Miller) is widely used to curb the metabolic complications. Till date, reports are not available for the side effects of A. vera. Several researchers are used to different solvents such as aqueous solution, alcohol, ethanol, and chloroform for the A. vera extract preparations and studied their hypoglycemic and hypolipidemic effects in animal and human studies. Furthermore, little information was recorded with the active compounds extracted from the A. vera and their anti-obesity and antidiabetic effects in clinical studies. In this review, we made an attempt to compile all the available literature by using different search engines (PubMed, Scopus, and Google Scholar) on the A. vera extract preparations and the possible mechanism of action involved in carbohydrate and lipid metabolism. PMID:26666199

  5. Cytotoxicity study of plant Aloe vera (Linn

    Directory of Open Access Journals (Sweden)

    Atul N Chandu

    2012-01-01

    Full Text Available Background: The objective of this study has been to evaluate the in-vitro antitumor activity of Aloe vera extract of in cultured B16F10 melanoma cell line by measuring cell viability using "Trypan blue exclusion assay" method. Aim: To find out such kind of anticancer drug which is a cheap, safe, less toxic, and more potent drug compared to chemotherapy drug. Materials and Methods: In-vitro antitumor activity cell culture1, drug treatment (standard and test extract and Trypan blue exclusion assay growth and viability test 1 were used. Treatment of Aloe vera extract against B16F10 melanoma cell line, in all concentration range, showed decrease in percent cell viability, as compared to that of negative when examined by "Trypan blue exclusion assay". Results: In overall variation of test samples, Aloe vera extract showed its best activity in the concentration of 300 μg/ml, which was approximately equal to the activity of standard drug doxorubicin. Evaluation of in-vitro antitumor activity revealed that Aloe vera extract exhibits good cytotoxic activity. The best cytotoxic activity by Aloe vera was shown at 200 μg/ml concentration. Conclusion: The study of cytoprotection against normal cells by micronucleus assay has shown that the herbal extracts have less toxic effects to the normal blood lymphocytes, as compared to that of standard anticancer drug.

  6. α -Mangostin from Cratoxylum arborescens (Vahl) Blume Demonstrates Anti-Ulcerogenic Property: A Mechanistic Study.

    Science.gov (United States)

    Sidahmed, Heyam M A; Abdelwahab, Siddig Ibrahim; Mohan, Syam; Abdulla, Mahmood Ameen; Mohamed Elhassan Taha, Manal; Hashim, Najihah Mohd; Hadi, A Hamid A; Vadivelu, Jamunarani; Loke Fai, Mun; Rahmani, Mawardi; Yahayu, Maizatulakmal

    2013-01-01

    Cratoxylum arborescens (Vahl) Blume is an Asian herbal medicine with versatile ethnobiological properties including treatment of gastric ulcer. This study evaluated the antiulcerogenic mechanism(s) of α -mangostin (AM) in a rat model of ulcer. AM is a prenylated xanthone derived through biologically guided fractionation of C. arborescens. Rats were orally pretreated with AM and subsequently exposed to acute gastric lesions induced by ethanol. Following treatment, ulcer index, gastric juice acidity, mucus content, histological and immunohistochemical analyses, glutathione (GSH), malondialdehyde (MDA), nitric oxide (NO), and nonprotein sulfhydryl groups (NP-SH) were evaluated. The anti-Helicobacter pylori, cyclooxygenase-2 (COX-2) inhibitory effect, and antioxidant activity of AM were also investigated in vitro. AM (10 and 30 mg/kg) inhibited significantly (P < 0.05) ethanol-induced gastric lesions by 66.04% and 74.39 %, respectively. The compound induces the expression of Hsp70, restores GSH levels, decreases lipid peroxidation, and inhibits COX-2 activity. The minimum inhibitory concentration (MIC) of AM showed an effective in vitro anti-H. pylori activity. The efficacy of the AM was accomplished safely without presenting any toxicological parameters. The results of the present study indicate that the antioxidant properties and the potent anti-H. pylori, in addition to activation of Hsp70 protein, may contribute to the gastroprotective activity of α -mangostin. PMID:23634169

  7. α-Mangostin from Cratoxylum arborescens (Vahl Blume Demonstrates Anti-Ulcerogenic Property: A Mechanistic Study

    Directory of Open Access Journals (Sweden)

    Heyam M. A. Sidahmed

    2013-01-01

    Full Text Available Cratoxylum arborescens (Vahl Blume is an Asian herbal medicine with versatile ethnobiological properties including treatment of gastric ulcer. This study evaluated the antiulcerogenic mechanism(s of α-mangostin (AM in a rat model of ulcer. AM is a prenylated xanthone derived through biologically guided fractionation of C. arborescens. Rats were orally pretreated with AM and subsequently exposed to acute gastric lesions induced by ethanol. Following treatment, ulcer index, gastric juice acidity, mucus content, histological and immunohistochemical analyses, glutathione (GSH, malondialdehyde (MDA, nitric oxide (NO, and nonprotein sulfhydryl groups (NP-SH were evaluated. The anti-Helicobacter pylori, cyclooxygenase-2 (COX-2 inhibitory effect, and antioxidant activity of AM were also investigated in vitro. AM (10 and 30 mg/kg inhibited significantly (P<0.05 ethanol-induced gastric lesions by 66.04% and 74.39 %, respectively. The compound induces the expression of Hsp70, restores GSH levels, decreases lipid peroxidation, and inhibits COX-2 activity. The minimum inhibitory concentration (MIC of AM showed an effective in vitro anti-H. pylori activity. The efficacy of the AM was accomplished safely without presenting any toxicological parameters. The results of the present study indicate that the antioxidant properties and the potent anti-H. pylori, in addition to activation of Hsp70 protein, may contribute to the gastroprotective activity of α-mangostin.

  8. ALOS satellite imagery utilization for safeguards

    International Nuclear Information System (INIS)

    This paper introduces examples of satellite imageries analysis and utilizations for safeguards activities. Recently, many kinds of satellite imageries are available in the world i.e., high-spatial resolution, multi- and hyper-spectral, multi-function, and multi-polarization radars. The problem is that how to obtain the required information from these digital images. The Japan Aerospace Exploration Agency (JAXA) has successfully launched the Advanced Land Observing Satellite (ALOS, nicknamed 'Daichi') on 24 January, 2006. The mission objectives are cartography, regional observation, disaster monitoring etc. ALOS has three instruments, PRISM, AVNIR-2, and PALSAR, to achieve these objectives. The ALOS research program can be categorized into two main parts of the ALOS mission: calibration and validation (Cal/Val), and application and science. We are presently carrying out the initial calibration and validation works for each instrument. It is very important to improve the absolute accuracy and image quality of the products. We establish and organize the international ALOS Cal/Val and science team (CVST) to do these works effectively. Based on the CVST activities, we are setting test sites and reference facilities in the world, and considering mission operation plans of each instrument to observe the test sites. The application and scientific results will demonstrate the ALOS data utilization capability. We define the digital surface model (DSM), ortho-rectified images for each sensor, and the surface deformation map as high-level and research products. In particular, geographical information such as elevation, topography, land use and land cover maps are necessary as basic information in many fields of practical applications and research areas. This paper describes our research and scientific activities including some preliminary results of calibration and validation, and examples of acquired images and high-level products related to geographical information. (author)

  9. Propagation Techniques and Agronomic Requirements for the Cultivation of Barbados Aloe (Aloe vera (L.) Burm. F.)—A Review

    Science.gov (United States)

    Cristiano, Giuseppe; Murillo-Amador, Bernardo; De Lucia, Barbara

    2016-01-01

    Barbados aloe (Aloe vera (L.) Burm. F.) has traditionally been used for healing in natural medicine. However, aloe is now attracting great interest in the global market due to its bioactive chemicals which are extracted from the leaves and used in industrial preparations for pharmaceutical, cosmetic, and food products. Aloe originated from tropical and sub-tropical Africa, but it is also now cultivated in warm climatic areas of Asia, Europe, and America. In this review, the most important factors affecting aloe production are described. We focus on propagation techniques, sustainable agronomic practices and efficient post harvesting and processing systems. PMID:27721816

  10. Conservación de mango Tommy atkins mínimamente procesado mediante un recubrimiento comestible de aloe vera (Aloe barbadensis Miller)

    OpenAIRE

    Pérez Tamayo, Andrés Felipe

    2015-01-01

    Resumen: la implementación de técnicas de conservación y procesamiento, económicamente viables, que preserven las características de calidad de los alimentos y de las cuales se obtengan diferentes productos con valor agregado, son algunos de los retos que a nivel agroindustrial presentan frutos como el mango para fomentar su consumo y evitar pérdidas en poscosecha debidas a la sobreproducción o a las deficiencias en los sistemas de comercialización. Las frutas mínimamente procesadas (IV Gama)...

  11. The effects of Aloe vera (Aloe barbadensis) coating on the quality of shrimp during cold storage.

    Science.gov (United States)

    Soltanizadeh, Nafiseh; Mousavinejad, Mohsen S

    2015-10-01

    Green tiger shrimp (Penaeus semisulcatus) is an important aquaculture species worldwide. Its perishable nature, however, needs preservation methods to ensure its quality and shelf life. In this study, the effects of Aloe vera coating on the quality and shelf life of shrimps during cold storage were investigated. Shrimp samples were dipped in aqueous solutions containing 25%, 50%, 75%, and 100% Aloe vera gel before storage at 4 °C for 7 days. Drip loss, pH, TBA, TVB-N, and texture of both the control and treated shrimp samples were analyzed periodically. There were significant differences between coated shrimps and the control group in all parameters evaluated. Aloe vera at 75% and 100% concentrations was able to prevent lipid oxidation and drip loss properly; however, coatings containing 25% Aloe vera did not have the desired effects on these characteristics. Shrimps coated with higher concentrations of Aloe vera had better textural properties during cold storage. Results also indicated the positive effects of Aloe vera coating on the sensory quality of shrimp.

  12. The effects of Aloe vera (Aloe barbadensis) coating on the quality of shrimp during cold storage.

    Science.gov (United States)

    Soltanizadeh, Nafiseh; Mousavinejad, Mohsen S

    2015-10-01

    Green tiger shrimp (Penaeus semisulcatus) is an important aquaculture species worldwide. Its perishable nature, however, needs preservation methods to ensure its quality and shelf life. In this study, the effects of Aloe vera coating on the quality and shelf life of shrimps during cold storage were investigated. Shrimp samples were dipped in aqueous solutions containing 25%, 50%, 75%, and 100% Aloe vera gel before storage at 4 °C for 7 days. Drip loss, pH, TBA, TVB-N, and texture of both the control and treated shrimp samples were analyzed periodically. There were significant differences between coated shrimps and the control group in all parameters evaluated. Aloe vera at 75% and 100% concentrations was able to prevent lipid oxidation and drip loss properly; however, coatings containing 25% Aloe vera did not have the desired effects on these characteristics. Shrimps coated with higher concentrations of Aloe vera had better textural properties during cold storage. Results also indicated the positive effects of Aloe vera coating on the sensory quality of shrimp. PMID:26396412

  13. [Charles Miller Fisher: a giant of neurology].

    Science.gov (United States)

    Tapia, Jorge

    2013-08-01

    C. Miller Fisher MD, one of the great neurologists in the 20th century, died in April 2012. Born in Canada, he studied medicine at the University of Toronto. As a Canadian Navy medical doctor he participated in World War II and was a war prisoner from 1941 to 1944. He did a residency in neurology at the Montreal Neurological Institute between 1946 and 1948, and later on was a Fellow in Neurology and Neuropathology at the Boston City Hospital. In 1954 he entered the Massachusetts General Hospital as a neurologist and neuropathologist, where he remained until his retirement, in 2005. His academic career ended as Professor Emeritus at Harvard University. His area of special interest in neurology was cerebrovascular disease (CVD). In 1954 he created the first Vascular Neurology service in the world and trained many leading neurologists on this field. His scientific contributions are present in more than 250 publications, as journal articles and book chapters. Many of his articles, certainly not restricted to CVD, were seminal in neurology. Several concepts and terms that he coined are currently used in daily clinical practice. The chapters on CVD, in seven consecutive editions of Harrison's Internal Medicine textbook, are among his highlights. His death was deeply felt by the neurological community.

  14. Arthur Miller Wins a Peace Prize: Teaching, Literature, and Therapy.

    Science.gov (United States)

    Kopald, Meredith

    1992-01-01

    Describes how a high school student was able to express powerful feelings and achieve some kind of reconciliation with his father through his therapeutic exploration of Arthur Miller's play "Death of a Salesman." (PRA)

  15. NOAA Ship Miller Freeman Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Miller Freeman Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  16. Derivados citotóxicos de vitanolidos isolados das folhas de Acnistus arborescens

    Directory of Open Access Journals (Sweden)

    Sandro Minguzzi

    2011-01-01

    Full Text Available In view of anticancer activity of 7 β-acetoxywithanolide D (2 and 7β-16α-diacetoxywithonide D (3, isolated from the leaves of Acnistus arborescens (Solanaceae, five withanolide derivatives were obtained and their structures were determined by NMR, MS and IV data analysis. The in vitro anticancer activity of these derivatives was evaluated in a panel of cancer cell lines: human breast (BC-1, human lung (Lu1, human colon (Col2 and human oral epidermoid carcinoma (KB. Compounds 2a (acetylation of 2, 3b (oxidation of 3 and 2c (hydrogenation of 2 exhibited the highest anticancer activity against human lung cancer cells, with ED50 values of 0.19, 0.25 and 0.63 μg/mL, respectively.

  17. Cytotoxic derivatives of withanolides isolated from the leaves of Acnistus arborescens

    International Nuclear Information System (INIS)

    In view of anticancer activity of 7 beta-acetoxywithanolide D (2) and 7beta-16beta-diacetoxywithonide D (3), isolated from the leaves of Acnistus arborescens (Solanaceae), five withanolide derivatives were obtained and their structures were determined by NMR, MS and IV data analysis. The in vitro anticancer activity of these derivatives was evaluated in a panel of cancer cell lines: human breast (BC-1), human lung (Lu1), human colon (Col2) and human oral epidermoid carcinoma (KB). Compounds 2a (acetylation of 2), 3b (oxidation of 3) and 2c (hydrogenation of 2) exhibited the highest anticancer activity against human lung cancer cells, with ED50 values of 0.19, 0.25 and 0.63 mug/mL, respectively. (author)

  18. ANTICARIES AND α-AMYLASE INHIBITORY ACTIVITY OF JASMINUM ARBORESCENS ROXB. (OLEACEAE LEAVES EXTRACT

    Directory of Open Access Journals (Sweden)

    Bhagath K

    2013-12-01

    Full Text Available The aim of the present study was to determine anti caries and α-amylase inhibitory activity of leaf extract of Jasminum arborescens Roxb. (Oleaceae. Anti caries activity was determined by Agar well diffusion assay against seven clinical isolates of Streptococcus mutans (Sm-01 to Sm-07 recovered from dental caries subjects. Enzyme inhibitory activity was tested against α-amylase by spectrophometric method using starch as substrate. The extract exhibited dose dependent inhibition against cariogenic isolates. Among seven isolates, isolate Sm-04 and Sm-06 were inhibited to higher and least extent respectively. The extract was found to cause inhibition of α-amylase activity in a dose dependent manner and its IC50 value was found to be 17.45 mg/ml. The inhibitory activity could be attributed to the presence of secondary metabolites. The plant may be a potential source for development of agents which are active against dental caries pathogens and for diabetes mellitus.

  19. SLN as a topical delivery system for Artemisia arborescens essential oil: In vitro antiviral activity and skin permeation study

    OpenAIRE

    Lai, Francesco; Sinico, Chiara; De Logu, Alessandro; Zaru, Marco; Müller, Rainer H.; Fadda, Anna M.

    2007-01-01

    The effect of SLN incorporation on transdermal delivery and in vitro antiherpetic activity of Artemisia arborescens essential oil was investigated. Two different SLN formulations were prepared using the hot – pressure homogenization technique, Compritol 888 ATO as lipid, and Poloxamer 188 and Miranol Ultra C32 as surfactants. Formulations were examined for their stability for two years by monitoring average size distribution and zeta potential values. The antiviral activity of free and SLN in...

  20. Processing of Aloe Vera Leaf Gel: A Review

    Directory of Open Access Journals (Sweden)

    C. T. Ramachandra

    2008-01-01

    Full Text Available Proper scientific investigations on Aloe vera have gained more attention over the last decade due to its reputable, medicinal, pharmaceutical and food properties. Some publications have appeared in reputable scientific journals that have made appreciable contributions to the discovery of the functions and utilizations of Aloe vera lacking processing of leaf gel. Present processing techniques aims at producing best quality aloe products but end aloe products contain very little or virtually no active ingredients. Hence, appropriate processing techniques should be employed during processing in order to extend the use of aloe vera gel. Further research needs to be done to unravel the myth surrounding the biological activity and the exploitation of aloe constituents.

  1. Antifungal activity of aloe vera gel against plant pathogenic fungi

    International Nuclear Information System (INIS)

    Aloe vera gel extracted from the Aloe vera leaves was evaluated for their antifungal activity at the rate of 0.15%, 0.25% and 0.35% concentration against five plants pathogenic fungi viz., Aspergillus niger, Aspergillus flavus, Alternaria alternata, Drechslera hawaiensis and Penicillum digitatum 0.35% concentration Aloe vera gel completely inhibited the growth of Drechslera hawaiensis and Alternaria alternata. (author)

  2. Allionrs Aloe names (Asphodelaceae: nomenclature and typification

    Directory of Open Access Journals (Sweden)

    L. Gugliemone

    2009-12-01

    Full Text Available The taxa belonging to the genus Aloe published in Synopsis methodica stirpium horti regii taurinensis (Allioni 1760 and in Auctarium ad synopsim meihodicam stirpium horti regii taurinensis (Allioni 1773 were examined. The protologues of Aloe maculata All. and A. verrucosospinosa All. are analysed and lectotypes designated. The homonymy of A. succotrina All. w ith A. succotrina Weston (1770 is recognized, and the lectotype o f this last name designated. Epitypes are selected to fix the application of all three names. Short differential diagnoses o f the three species are given and their distribution ranges discussed; distribution maps based on specimens held in the South African National Herbarium (PRE, KwaZulu-Natal Herbarium (NH. Compton Herbarium (NBG and the South African Museum Collection (SAM held in NBG are provided.

  3. 日本芦荟试管快速繁殖研究%Study on the Celerity Propagation of Aloe Arborescens Mill in Test Tube

    Institute of Scientific and Technical Information of China (English)

    马晓梅

    2007-01-01

    以日本芦荟的茎段为外植体进行试管培养,经试验筛选出各培养段最适宜的培养基为:(1)腋芽萌生,MS+6-BA 2.5 mg/L+IBA 0.3 mg/L;(2)丛生芽的分化与继代,MS+6-BA 2.0 mg/L+IBA 0.3 mg/L;(3)生根,1/2MS+IBA2.0 mg/L.炼苗成活的关键是适宜的培养土、温度和较高湿度.本试验经炼苗阶段,成活率达100%.

  4. Effects of Light on Anthraquinones of Aloe arborescens%光质对木立芦荟蒽醌类物质的影响

    Institute of Scientific and Technical Information of China (English)

    王红星; 郭翠红; 李景原

    2009-01-01

    [目的]研究光质处理对木立芦荟中蒽醌类物质的影响.[方法] 运用植物化学法和HPLC技术研究红、蓝和黄光处理对木立芦荟中蒽醌类物质的影响.[结果] 3种光质处理均能导致总蒽醌、芦荟素和芦荟大黄素含量增加,黄光更利于总蒽醌、芦荟素的积累,蓝光利于芦荟大黄素的积累. [结论] 研究结果可为我国北方芦荟栽培提供指导.

  5. Quality control on the Polysaccharides in the Aloe Arborescens from Fujian%闽产木立芦荟多糖的质量控制

    Institute of Scientific and Technical Information of China (English)

    陈丹; 王二丽; 叶静; 吴熙; 包国荣; 张小玲; 龚碧栋

    2005-01-01

    目的:建立并优化闽产木立芦荟多糖的含量测定方法条件.方法:以闽产木立芦荟多糖含量为指标,苯酚-硫酸法为测定方法,采用重复正交试验法优选最佳测定条件.结果:苯酚和硫酸的用量、反应温度均对含量测定有显著影响,对反应时间的影响小,平均回收率为97.35%,RSD=1.62%(n=6).结论:优选后方法灵敏度高,重现性好,适用于闽产木立芦荟多糖的质量控制.

  6. 木立芦荟的试管苗快速繁殖%Tissue Culture and Rapid Propagation of Aloe arborescens

    Institute of Scientific and Technical Information of China (English)

    曾宋君; 彭晓明

    2000-01-01

    以木立芦荟茎尖、腋芽、叶片、吸芽为外植体的离体培养和快速繁殖研究结果表明:所有外植体在合适培养基上均能产生愈伤组织与丛生芽,初代培养的最适培养基为MS+6BA 3.0 mg/L+NAA0.2 mg/L;继代培养的最适培养基为MS+6-BA 2.0 mg/L+NAA 0.2 mg/L;生根壮苗的最适培养基为1/2MS+NAA 0.5 mg/L.试管苗移栽的成活率可达到100%.商品化生产中以白糖、片糖代替蔗糖,以卡拉胶代替琼脂具有相同的结果.

  7. Study on tissue culture and plant regeneration of Aloe arborescens Mill%木立芦荟组织培养及植株再生的研究

    Institute of Scientific and Technical Information of China (English)

    李佳; 王震宇; 乔彬; 张智源

    2010-01-01

    以木立芦荟的茎尖为外植体,接种于不同激素配比的MS固体培养基上,通过直接器官发生和间接器官发生两种方式获得再生植株.试验结果表明:直接诱导不定芽的最佳诱导培养基为MS+6-BA4.0 ng/L+NAA 0.1 mg/L,平均芽数可达3.67;间接诱导过程中,愈伤组织诱导的最佳培养基是MS+BA 2.0 mg/L+IBA 0.2 mg/L,诱导率为100%;不定芽生根的最佳培养基为1/2 MS+NAA 0.1-0.2 mg/L;在培养基中添加0.2%的活性炭可有效抑制外植体褐化;组培苗炼苗20余天,将其盆栽,成活率可达80%.

  8. 单杆芦荟离体快速繁殖技术研究%Studies on the techniques of rapid propagation of Aloe arborescens Mill. in vitro

    Institute of Scientific and Technical Information of China (English)

    李玉巧; 仲磊; 吴纲

    2001-01-01

    单杆芦荟离体快速繁殖,芽增殖培养基以MS+BA 2.5 mg/L+NAA 0.2~0.3 mg/L,生根培养基以1/2MS+NAA 2.0 mg/L+活性炭0.2%~0.3%,壮苗培养基以1/2MS+IBA 2.0 mg/L为好.培养温度以28 ℃最佳.快速繁殖方法用分叶法比常用的分株、分芽方法,繁殖系数高.培养出的壮苗移栽于河沙中,成活率一般在80%以上.

  9. Tissue Culture of Aloe arborescens Mill%木立芦荟的组织培养及快速繁殖

    Institute of Scientific and Technical Information of China (English)

    吴红芝

    2000-01-01

    以木立芦荟的叶片、叶鞘和带腋芽的茎段为外植体进行试管培养,结果表明,叶鞘和茎段可诱导形成愈伤组织,腋芽直接萌生.经试验筛选出各培养阶段最适宜的培养基为:(1)愈伤组织诱导,MS+6-BA 2.5 mg/L+NAA 0.15 mg/L;(2)腋芽萌生,MS+6-BA 2.0 m g/L+NAA 0.15 mg/L;(3)丛生芽分化及继代,MS+6-BA 2.0 mg/L+NAA 0.10 mg/L;(4)生根,MS+6-BA 0.3~0.5 mg/L+IBA 0.2 mg/L+活性碳 0.5%.

  10. ULTRACYTOCHEMICAL STUDIES OF ALOIN IN ALOE ARBORESCENS LEAVES%木立芦荟叶内芦荟素的超微细胞化学研究

    Institute of Scientific and Technical Information of China (English)

    廖海民; 沈宗根; 盛仙永; 胡正海

    2006-01-01

    使用醋酸铅溶液对木立芦荟叶的药用成分芦荟素进行细胞化学定位,在透射电镜下探讨芦荟素产生、转运和贮藏的过程.结果表明:芦荟素由同化薄壁组织产生,质体的类囊体为其合成部位.通过质体膜形成的小泡转移到周围的内质网,以后内质网小泡与质膜融合;或质体小泡直接与质膜融合.通过胞吐作用将芦荟素释放到质膜外,经质外体途径到达维管束的鞘细胞.在鞘细胞中,芦荟素经内质网小泡转移至内切向壁,由胞间连丝运输到芦荟素细胞的细胞质,最终贮藏在芦荟素细胞的液泡中.

  11. Study on Extraction Technology of Polysaccharide in Aloe arborescens Mill%木立芦荟多糖提取工艺研究

    Institute of Scientific and Technical Information of China (English)

    韩秋菊; 王美珠

    2013-01-01

    采用热水浸提法提取木立芦荟多糖,通过正交试验优化提取工艺,分析其主要的影响因素.结果显示,最佳提取工艺条件为:浸提温度70℃、浸提时间4h、料液比1:20、提取次数3次.在此工艺条件下木立芦荟多糖的提取率达5.48%.

  12. 木立芦荟离体快繁的研究%Study on the high - speed reproduction of in vitro Aloe arborescens Mill

    Institute of Scientific and Technical Information of China (English)

    李先芳; 王文静

    2001-01-01

    用木立芦荟茎段为外植体进行快繁试验.结果表明,MS适宜不定芽分化,MS+BA 3.0 mg/L+NAA 0.1 mg/L为最适宜增殖培养基,光照时间及光照强度影响不定芽分化,继代次数以3-7代为好,适宜的生根培养基是1/2 MS+NAA 2.0-5.0 mg/L+BA 0.01 mg/L.

  13. Tissue culture and karyotype analysis of Aloe arborescens Mill%木立芦荟的试管快速繁殖及核型分析

    Institute of Scientific and Technical Information of China (English)

    曲春香; 沈颂东; 孟祥勋; 许宏庆

    2002-01-01

    以木立芦荟的茎尖和茎段为外植体,筛选出不定芽诱导及增殖的培养基分别为MS+6-BA 3mg/L+IBA 0.5mg/L、MS+6-BA 2mg/L+IBA 0.5mg/L;生根培养基是MS+NAA 0.5mg/L.以试管苗的不定根为实验材料,进行压片,分析细胞分裂中期的显微照片,按Levan方法分类结果表明,木立芦荟的核型为k(2n)=6St+8Sm.

  14. 木立芦荟丛生芽诱导与植株再生%Adventitious shoots induction and plant regeneration of Aloe arborescens mill

    Institute of Scientific and Technical Information of China (English)

    代容春; 朱锦懋; 陈由强; 林荣华

    2001-01-01

    取木立芦荟带节的嫩茎作外植体,培养于附加不同种类和激素浓度的MS培养基上.在附加6-BA2.0mg/L+KT1.0mg/L+NAA0.4mg/L时,丛生芽诱导效果最佳,数量最多;在附加6-BA1.0mg/L+NAA0.2mg/L时,丛生芽长势最好,芽长且健壮;在附加NAA0.4mg/L时,生根效果最佳.当苗高3.0cm以上,根长达2.0cm以上时,打开瓶盖锻炼3d后,移栽于蛭石:河砂:腐叶土=2:2:1的混合基质土壤中,成活率达93.2%.

  15. 木立芦荟的试管繁殖技术%On the Tissue Culture Technology of Aloe arborescens Mill

    Institute of Scientific and Technical Information of China (English)

    李余先; 朱宝娣; 吴南

    2010-01-01

    探讨了木立芦荟的试管繁殖技术过程,从初代培养的建立、取材与消毒、培养条件、扩大繁殖、生根与壮苗、试管苗的移栽与管理几个方面进行了详细的论述,为进行木立芦荟的试管繁殖提供参考.

  16. In vitro and in vivo antioxidant activities of polysaccharide purified from aloe vera (Aloe barbadensis) gel.

    Science.gov (United States)

    Kang, Min-Cheol; Kim, Seo Young; Kim, Yoon Taek; Kim, Eun-A; Lee, Seung-Hong; Ko, Seok-Chun; Wijesinghe, W A J P; Samarakoon, Kalpa W; Kim, Young-Sun; Cho, Jin Hun; Jang, Hyeang-Su; Jeon, You-Jin

    2014-01-01

    The in vitro and in vivo antioxidant potentials of a polysaccharide isolated from aloe vera gel were investigated. Enzymatic extracts were prepared from aloe vera gel by using ten digestive enzymes including five carbohydrases and five proteases. Among them, the highest yield was obtained with the Viscozyme extract and the same extract showed the best radical scavenging activity. An active polysaccharide was purified from the Viscozyme extract using ethanol-added separation and anion exchange chromatography. Purified aloe vera polysaccharide (APS) strongly scavenged radicals including DPPH, hydroxyl and alkyl radicals. In addition, APS showed a protective effect against AAPH-induced oxidative stress and cell death in Vero cells as well as in the in vivo zebrafish model. In this study, it is proved that both the in vitro and in vivo antioxidant potentials of APS could be further utilized in relevant industrial applications.

  17. Pairing Relationships Among Feldspathic Lunar Meteorites from Miller Range, Antarctica

    Science.gov (United States)

    Zeigler, Ryan A.; Korotev, R. L.; Jolliff, B. L.

    2012-01-01

    The Miller Range ice fields have been amongst the most prolific for lunar meteorites that ANSMET has searched [1-3]. Six different stones have been recovered during the 2005, 2007, and 2009 field seasons: MIL 05035 (142 g), MIL 07006 (1.4 g), MIL 090034 (196 g), MIL 090036 (245 g), MIL 090070 (137 g), and MIL 090075 (144 g). Of these, the five stones collected during the 2007 and 2009 seasons are feldspathic breccias. Previous work on the Miller Range feldspathic lunar meteorites (FLMs) has suggested that they are not all paired with each other [4-5]. Here we examine the pairing relationships among the Miller Range FLMs using petrography in concert with traceand major-element compositions.

  18. New Insights into Prebiotic Chemistry from Old Archived Miller Extracts

    Science.gov (United States)

    Parker, Eric T.; Cleaves, H. James; Dworkin, Jason P.; Glavin, Daniel P.; Callahan, Michael P.; Aubrey, Andrew D.; Lazcano, Antonio; Bada, Jeffrey L.

    2011-01-01

    Following the discovery of an archived set of samples from Stanley Miller's early experiments, analyses were undertaken to better understand the diversity of compounds produced from electric discharges acting on reducing gas mixtures. The paper chromatography methods that Miller used in the 1950s were only capable of detecting a few amino acids and were unable to provide substantial quantitative data relative to today's techniques. Current analytical techniques are much more sensitive and selective, and are capable of precisely quantifying a much larger range of amino acids and their enantiomeric abundances. In one study, preserved dried samples produced by Miller using a lesser-known volcanic apparatus which differed from Miller's classic apparatus in that it utilized an aspirator that injected steam into the electric discharge chamber, simulating a volcanic eruption. The volcanic apparatus produced a wider variety of amino acids than the classic configuration. Prebiotic compounds synthesized in these environments may have locally accumulated where they could have undergone further processing. An additional preserved set of samples from an experiment conducted in 1958 were also found in Miller's archived collection. These samples which had been generated using a mixture of CH4, NH3, H2S and CO2 were collected, catalogued, and stored by Miller, but for unknown reasons were never studied. In our analyses a total of 23 amino acids and 4 amines, including 7 organosulfur compounds, were detected in these samples. The major amino acids with chiral centers are racemic within the accuracy of the measurements, indicating that they are not contaminants introduced during sample storage. This experiment marks the first synthesis of sulfur amino acids from spark discharge experiments designed to imitate primordial environments. The relative yield of some amino acids, in particular the isomers of amino butyric acid, are the highest ever found in a spark discharge experiment

  19. 芦荟凝集素提取及促免疫活性功能初步研究%Study of purification of lectins from species of aloe

    Institute of Scientific and Technical Information of China (English)

    田兵; 王关林; 方宏筠

    2001-01-01

    分别从3种有经济价值的芦荟品种,即中华芦荟(Aloe vera L.ver. chinensis(Haw) )、库拉索芦荟(Aloe barbadensis Mill)和木立芦荟(Aloe arborescens Mill)中采用凝胶层析法提取了3种凝集素:Lec1、Lec2和Lec3,经过聚丙烯酰胺凝胶电泳分析其为单一成分的糖蛋白.比较了3种凝集素的糖和蛋白的含量,得出库拉索芦荟凝集素Lec2糖含量最高,木立芦荟凝集素Lec3蛋白含量最高.免疫学实验证明,库拉索芦荟凝集素的凝集效价最高,其次为木立芦荟、中华芦荟.3种凝集素对淋巴细胞转化功能都有明显的促进作用,其中库拉索芦荟凝集素Lec2的促淋巴细胞转化率最高.因此芦荟凝集素在治疗免疫功能低下方面可能有一定的应用价值.

  20. Aloe vera as a functional ingredient in foods.

    Science.gov (United States)

    Rodríguez Rodríguez, Elena; Darias Martín, Jacinto; Díaz Romero, Carlos

    2010-04-01

    The main scientific discoveries on Aloe vera published mainly in the last three decades are presented in this work. After describing Aloe from a botanical point of view, the papers related with the chemical composition of different parts of the leaf of Aloe, particularly those in which the gel is described and are presented in a synthetic manner. The chemical analyses reveal that Aloe gel contains mannose polymers with some glucose and other sugars, among which the most important is Acemannan. Besides these, other components such as glycoproteins, enzymes, amino acids, vitamins, and minerals are described. Different factors also affecting the chemical composition of the gel, such as species and variety, climatic and soil conditions, cultivation methods, processing and preservation, are enumerated and discussed. On the other hand, the main therapeutic applications have been revised and the possible damaging effects of Aloe are also commented upon. A special emphasis is placed on the biologically active compounds or groups of compounds responsible for the therapeutic applications and which are their action mechanisms. The paper concludes that more research is needed to confirm the therapeutic and beneficial effects and to definitively clarify the myth surrounding Aloe vera. A general view on the problem of the commercialization and establishment of the quality and safety of Aloe products in the food industry has been offered here. The main points and European regulations that need to be considered regarding the quality control of prepared Aloe products are presented in this paper. PMID:20301017

  1. Qualitative improvement of low meat beef burger using Aloe vera.

    Science.gov (United States)

    Soltanizadeh, Nafiseh; Ghiasi-Esfahani, Hossein

    2015-01-01

    Low meat beef burgers have found their niche in the food markets in developing countries because of their lower price. However, these burgers still lack an acceptable quality. This study investigates the effects of different concentrations of Aloe vera on the quality of this food product. For this purpose, beef burgers were produced with 0%, 1%, 3%, and 5% Aloe vera and the changes in their cooking parameters, lipid oxidation, texture, and appeal to consumers over 7days of refrigerated storage were evaluated. Results indicate that Aloe vera contributed to some extent to decreased cooking loss and diameter reduction in the burgers. Increased concentrations of Aloe vera led to improvements in the water absorption and texture of the burgers as well as their lipid stability. However, a concentration level of 3% led to the most acceptability of the product to the panelists. Finally, it was found that Aloe vera acts as a hydrocolloid and improves the quality of burgers.

  2. Aloe vera: A review of toxicity and adverse clinical effects.

    Science.gov (United States)

    Guo, Xiaoqing; Mei, Nan

    2016-04-01

    The Aloe plant is employed as a dietary supplement in a variety of foods and as an ingredient in cosmetic products. The widespread human exposure and its potential toxic and carcinogenic activities raise safety concerns. Chemical analysis reveals that the Aloe plant contains various polysaccharides and phenolic chemicals, notably anthraquinones. Ingestion of Aloe preparations is associated with diarrhea, hypokalemia, pseudomelanosis coli, kidney failure, as well as phototoxicity and hypersensitive reactions. Recently, Aloe vera whole leaf extract showed clear evidence of carcinogenic activity in rats, and was classified by the International Agency for Research on Cancer as a possible human carcinogen (Group 2B). This review presents updated information on the toxicological effects, including the cytotoxicity, genotoxicity, carcinogenicity, and adverse clinical effects of Aloe vera whole leaf extract, gel, and latex.

  3. Monosaccharide analysis of succulent leaf tissue in Aloe

    DEFF Research Database (Denmark)

    Grace, Olwen Megan; Dzajic, Amra; Jäger, Anna;

    2013-01-01

    Introduction – The succulent leaf mesophyll in Aloe species supports a burgeoning natural products industry, particularly in Africa. Comparative data necessary to prioritise species with economic potential have been lacking. Objective – To survey leaf mesophyll monosaccharide composition...... in the genus Aloe using a predictive phylogenetic approach. Methodology – Monosaccharide composition was assessed in 31species, representing the morphological and taxonomic diversity of Aloe sensu stricto. Leaf mesophyll polysaccharides were partially hydrolysed in a trifluoroacetic acid (TFA)-SilA assay...... species, and xylose in one species (Aloidendron pillansii). Three monosaccharides therefore account for 90% of the variation in leaf mesophyll in Aloe. Species which do not share this typical monosaccharide profile appear to group outside the core Aloe clade in the phylogeny. Conclusion – Preliminary...

  4. Aloe vera: A review of toxicity and adverse clinical effects.

    Science.gov (United States)

    Guo, Xiaoqing; Mei, Nan

    2016-04-01

    The Aloe plant is employed as a dietary supplement in a variety of foods and as an ingredient in cosmetic products. The widespread human exposure and its potential toxic and carcinogenic activities raise safety concerns. Chemical analysis reveals that the Aloe plant contains various polysaccharides and phenolic chemicals, notably anthraquinones. Ingestion of Aloe preparations is associated with diarrhea, hypokalemia, pseudomelanosis coli, kidney failure, as well as phototoxicity and hypersensitive reactions. Recently, Aloe vera whole leaf extract showed clear evidence of carcinogenic activity in rats, and was classified by the International Agency for Research on Cancer as a possible human carcinogen (Group 2B). This review presents updated information on the toxicological effects, including the cytotoxicity, genotoxicity, carcinogenicity, and adverse clinical effects of Aloe vera whole leaf extract, gel, and latex. PMID:26986231

  5. Qualitative improvement of low meat beef burger using Aloe vera.

    Science.gov (United States)

    Soltanizadeh, Nafiseh; Ghiasi-Esfahani, Hossein

    2015-01-01

    Low meat beef burgers have found their niche in the food markets in developing countries because of their lower price. However, these burgers still lack an acceptable quality. This study investigates the effects of different concentrations of Aloe vera on the quality of this food product. For this purpose, beef burgers were produced with 0%, 1%, 3%, and 5% Aloe vera and the changes in their cooking parameters, lipid oxidation, texture, and appeal to consumers over 7days of refrigerated storage were evaluated. Results indicate that Aloe vera contributed to some extent to decreased cooking loss and diameter reduction in the burgers. Increased concentrations of Aloe vera led to improvements in the water absorption and texture of the burgers as well as their lipid stability. However, a concentration level of 3% led to the most acceptability of the product to the panelists. Finally, it was found that Aloe vera acts as a hydrocolloid and improves the quality of burgers. PMID:25282702

  6. Determination of Aloin Content in Aloe with HPLC and Analysis of Aloe Chromatogram%HPLC法测定芦荟中芦荟苷的含量及其色谱图特征分析

    Institute of Scientific and Technical Information of China (English)

    杨素萍; 田嘉铭; 孙东晓; 甄攀

    2012-01-01

    [Objective] To establish a HPLC method for determining the content of aloin in 5 species of Aloe, and analyze their chromato-grams, so as to distinguish them from each other. [ Method] The content of aloin in sample solutions of Aloe species prepared using ultrasonic wave method was measured by HPLC. And, the chromatograms of Aloe were obtained. [ Result] The linear regression equation of aloin was Y = 13- 168 4X-2. 855 4, R =0.999 8, showing good linearity between concentration and peak area in the range of2.92 to 46.67 μg/ml. The average recovery rate was 108.0%. The content of aloin was614.3 μg/g for A. arborescens, 212.5 u-g/g for A. deiaetii, 135.3 μg/g tor A. vera L. , 72.92 μ/g for A. vera L. var. chinesis (Haw. ) Berg, and 2. 622 μg/g for A. nobilis. Double peaks occurred al the retention time of 3 to 5 min in the HPLC chromatogram of .4. vera L. , the peak height of which was Blightly higher on the left, but this difference was not significant. Its double peaks were basically separated at the baseline. From then on, no obvious chromatographic peaks appeared on the chromatogram. In addition, the chromatogram of A. vera L. was similar to that of A. arborescens and very different from that of other three species. [ Conclusion] There is a clear difference in aloin level among 5 species of Aloe. Of these, the content of aloin in A. wborescms is the highest. The determination method is stable, accurate and quick. Five species of Aloe are distinguished from each other by means of chromatogram analysis.%[目的]建立芦荟中芦荟苷含量的HPLC测定方法,测定几种芦荟中芦荟苷的含量,并分析这几种芦荟色谱图的特征,从而将5种芦荟区分开采.[方法]采用超声振荡提取法制备样品溶液,并用HPLC测定芦荟苷的含量,得到芦荟色谱图.[结果]芦荟苷的线性回归方程为Y=13.168 4X-2.855 4,R=0.999 8,表明在2.92-46.67 μg/ml范围内,芦荟苷浓度与峰面积的线性关系良好,平均回收率为108.0

  7. Obscenity Law Since Miller: Another Troublesome Balancing Formula.

    Science.gov (United States)

    Haan, David H.

    A 1973 Supreme Court decision ("Miller v. California") established the system of defining obscenity on the local level according to the following criteria: first, prurient appeal and patent offensiveness are to be determined by a community rather than by a national standard; second, sexually explicit materials are judged obscene only if specified…

  8. Continued misinterpretation of confidence intervals : Response to Miller and Ulrich

    NARCIS (Netherlands)

    Morey, Richard D.; Hoekstra, Rink; Rouder, Jeffrey N.; Wagenmakers, Eric-Jan

    2015-01-01

    Miller and Ulrich (2015) critique our claim (Hoekstra et al., Psychonomic Bulletin & Review, 21(5), 1157–1164, 2014), based on a survey given to researchers and students, of widespread misunderstanding of confidence intervals (CIs). They suggest that survey respondents may have interpreted the state

  9. Changes in the cuticle and wax of the leaves during the development of aloe (Aloe arborescens Mill.)%木立芦荟发育过程中叶表皮角质膜和蜡质的变化

    Institute of Scientific and Technical Information of China (English)

    朱命炜; 王红星; 李建军; 李俊英; 王太霞; 李景原

    2004-01-01

    应用扫描电镜观察了不同发育阶段的木立芦荟叶表面角质膜、蜡质的形态结构.结果显示,在木立芦荟叶发育的早期,叶表面只有一层薄的角质膜,没有蜡质.随着叶的发育,角质膜逐渐增厚,在角质膜表面逐渐形成瘤状蜡质突起.当叶发育成熟时,表面覆盖有厚的角质膜,角质膜上分布有密集的瘤状蜡质.在叶表皮上分布有下陷的气孔,气孔上方的角质膜和蜡质呈筒状围绕在气孔四周.由于木立芦荟叶表气孔下陷,又覆盖着厚的角质膜和密集的蜡质,能有效地减少水分散失和增强叶片反射光辐射的能力,因此,芦荟能适应干旱、强光照的环境.

  10. ANTIMICROBIAL ACTIVITY OF ALOE VERA LEAF EXTRACT

    OpenAIRE

    Kedarnath; Kamble Kaveri M; Vishwanath B Chimkod; C. S. Patil

    2013-01-01

    The antimicrobial activity of aloe vera extract was tested against pathogenic bacteria like Staphylococcus aureus, Klebisella pneumonia and E.coli and fungi like Aspergillus niger and Candida at a dose of 1:20 mg/ml and 2:40 mg/ml by using cup plate diffusion method. Various solvents such as petroleum ether, chloroform and methanol were used for extracts. The results reveal that, methanol and petroleum ether at a dose of 20 mg/ml has showed significant activity against Klebisella pneumonia an...

  11. Cytotoxicity study of plant Aloe vera (Linn)

    OpenAIRE

    Atul N Chandu; Kumar, Santhosh C; Chiranjib Bhattacharjee; Subal Debnath

    2012-01-01

    Background: The objective of this study has been to evaluate the in-vitro antitumor activity of Aloe vera extract of in cultured B16F10 melanoma cell line by measuring cell viability using "Trypan blue exclusion assay" method. Aim: To find out such kind of anticancer drug which is a cheap, safe, less toxic, and more potent drug compared to chemotherapy drug. Materials and Methods: In-vitro antitumor activity cell culture1, drug treatment (standard and test extract) and Trypan blue exclusion a...

  12. 28 CFR 79.52 - Criteria for eligibility for claims by uranium millers.

    Science.gov (United States)

    2010-07-01

    ... uranium millers. 79.52 Section 79.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CLAIMS UNDER THE RADIATION EXPOSURE COMPENSATION ACT Eligibility Criteria for Claims by Uranium Millers § 79.52 Criteria for eligibility for claims by uranium millers. To establish eligibility for compensation...

  13. Wentworth Miller : "Minu edu saladus? Kunstniku hing ja bürokraadi pulss" / Wentworth Miller ; koost. Triin Tael

    Index Scriptorium Estoniae

    Miller, Wentworth

    2006-01-01

    Cannes'is hotellis Carlton toimunud pressikonverentsist, kus ajakirjanike küsimustele vastasid põnevusseriaali "Põgenemine" peaosatäitjad Wentworth Miller ja Dominic Purcell. Lisaks "Wentworth SL Õhtulehele : "Minu südame võitmiseks tuleb oodata" ja tutvustus "Wentworthi läbimurdefilm täna õhtul ETVs"

  14. 芦荟组织培养体系的建立%Study on Establishment of Tissue Culture System in Aloe vera

    Institute of Scientific and Technical Information of China (English)

    牛亚玲; 董健

    2011-01-01

    [目的] 建立一个比较合理和完善的芦荟组织培养体系,为大规模快速生产芦荟组织培养苗提供依据.[方法] 以木立芦荟和中国芦荟的叶、茎尖和根为外植体,接种于不同激素配比的MS和N6固体培养基上进行组织培养,研究不同培养基对芦荟组织培养的影响.[结果] 在不定芽诱导过程中,茎尖在培养基MS+ 6-BA 3.0 mg/L+ NAA 0.2 mg/L上的芽诱导率最高.在诱导生根过程中,以1/2MS为基本培养基,NAA浓度在0.2~0.3 mg/L时芦荟组织不定芽生根效果较好.[结论] 芦荟组培效果受到遗传基因型和外在培养条件的双重制约.%[Objective] The study aimed to establish a more reasonable and perfect tissue culture system of Aloe vera, which provided the basis for the large-scale rape production al A. Vera tissue culture seedlings. [Method] With the leaf, shoot apical and root of Aloe arborescens Mill and Aloe vera L. As the explants, they were inoculated on the MS and N6 mediums with different hormone matching to made for the tissue culture and the effects of different mediums on the tissue culture of A. Vera was studied. [Result] In the induced process of adventitious bud, the shoot apical induced on the medium of MS +6-BA 3. 0 mg/L + NAA 0. 2 mg/L got the highest bud induction rate. In the induced rooting process, with 1/2MS as the basic medium, when NAA was 0. 2-0.3 mg/L, the adventitious bud of/4, vera got better rooting effect. [Conclusion ] The effect of tissue culture of A. Vera suffered the double restriction of genetic type and the external culture conditions.

  15. Biology of Pelosina arborescens PEARCEY, 1914, with comparative notes on Astrorhiza limicola SANDAHL, 1857 (Foraminifera: Astrorhizidae)

    DEFF Research Database (Denmark)

    Cedhagen, Tomas

    1993-01-01

    of the test are adaptations that also protect against bioturbation and predation but may restrict the respiratory surface. Field observations and laboratory experiments under anoxic conditions show that P arborescens can live anaerobically. Histological analysis of the protoplasm revealed large amounts...

  16. The Miller assessment for preschoolers (MAP): an introduction and review.

    Science.gov (United States)

    Banus, B J

    1983-05-01

    With the implementation of Public Law 94-142, the Education for All Handicapped Children Act, early childhood screening responsibilities intensified for occupational therapists. Frustrations caused by the absence of adequate testing tools increased proportionately. Lucy Jane Miller began working in 1971 on a new standardized test to predict school-related problems and published the Miller Assessment for Preschoolers (MAP) in 1982. Because the MAP is a new addition to the field of preschool testing, this review will introduce the MAP to occupational therapists and give a general overview and critique of its administration, scoring, and standardization procedures. The MAP has potential for becoming a major screening test for preschool children if it does predict school-related problems. PMID:6191574

  17. Sound Employment in the Adapted Movie-Daisy Miller

    Institute of Scientific and Technical Information of China (English)

    钦白兰

    2009-01-01

    Daisy Miller is a 1974 Ameriean drama movie directed by Peter Bogdanovich.It iS an adaptation of the Henry James‘novella of the same name.The movie,conmimng many symbolic cinematic techniques,iS about a beautiful young American girl died of"Roman fever"in Europe.This paper is devoted to the cinematic sound employment in the movie-Daisy Miller,with a purpose to show how the movie employs different sounds,difierent from the novella.to activate its theme.From the cinematic sound perspective,the paper claims that as all adapted movie,cinematic sound employment deeps the thematic realization,subtly intriguing with James,for the audience.

  18. Character Contrast in Arthur Miller s Death of a Salesman

    Institute of Scientific and Technical Information of China (English)

    程欣

    2007-01-01

    "I regard the theater as a serious business, one that makes or should make man more human, which is to say, less alone."A great playwright of social philosophy, Arthur Miller advocates that the common man, and none of rank, is the tragic hero of modern times. His plays have always revealed before the public eyes the tragedy of the average American life, the psychology of the ordinary people, and their conflicts with the morality of society.

  19. Controversies and challenges of vaccination: an interview with Elizabeth Miller.

    Science.gov (United States)

    Miller, Elizabeth

    2015-01-01

    Although strong evidence exists that the benefits of vaccination by far outweigh potential adverse events, controversy still exists. This has led opponents of vaccination to question its safety, efficacy and necessity. In an interview with Professor Elizabeth Miller, we discuss the continuum of beliefs held by vaccine refusers and hesitators, the resulting health consequences, and ways in which health professionals and industry regulators can help promote transparency to better convey the substantial health benefits of vaccination. PMID:26472230

  20. A Portfolio of Nobel Laureates: Markowitz, Miller and Sharpe

    OpenAIRE

    Hal Varian

    1993-01-01

    Three pioneers of quantitative finance have now been justly honored: Harry Markowitz, Merton Miller, and William Sharpe received the Nobel Prize in Economic Science in 1990. From today's perspective it is hard to understand what finance was like before portfolio theory. Here I attempt to provide a very brief history of the quantitative revolution in finance, drawing upon P. Bernstein's Capital Ideas (1992) and accounts of the three Nobel laureates.

  1. Allionrs Aloe names (Asphodelaceae): nomenclature and typification

    OpenAIRE

    L. Gugliemone; Gallo, L.; Meregalli, M.; G. F. Smith; Figueiredo, E

    2009-01-01

    The taxa belonging to the genus Aloe published in Synopsis methodica stirpium horti regii taurinensis (Allioni 1760) and in Auctarium ad synopsim meihodicam stirpium horti regii taurinensis (Allioni 1773) were examined. The protologues of Aloe maculata All. and A. verrucosospinosa All. are analysed and lectotypes designated. The homonymy of A. succotrina All. w ith A. succotrina Weston (1770) is recognized, and the lectotype o f this last name designated. Epitypes are selected to fix the appl...

  2. Aloe vera: a systematic review of its clinical effectiveness.

    OpenAIRE

    Vogler, B K; Ernst, E.

    1999-01-01

    BACKGROUND: The use of aloe vera is being promoted for a large variety of conditions. Often general practitioners seem to know less than their patients about its alleged benefits. AIM: To define the clinical effectiveness of aloe vera, a popular herbal remedy in the United Kingdom. METHOD: Four independent literature searches were conducted in MEDLINE, EMBASE, Biosis, and the Cochrane Library. Only controlled clinical trials (on any indication) were included. There were no restrictions on the...

  3. Protective effect of Aloe vera on polymicrobial sepsis in mice.

    Science.gov (United States)

    Yun, Nari; Lee, Chan-Ho; Lee, Sun-Mee

    2009-06-01

    Sepsis is an acute life-threatening clinical condition and remains the major cause of death in intensive care units. The primary pathophysiologic event central to the septic response is an overwhelming activation of the inflammatory system and countervailing response from the anti-inflammatory system. However, the cause of this perturbation has yet to be elucidated. In this study, we report that Aloe vera therapeutically reverses the lethality induced by cecal ligation and puncture (CLP), a clinically relevant model of sepsis. The administration of Aloe vera ameliorated the multiple organ dysfunction syndrome, as evidenced by the serum levels of biochemical parameters and histological changes. In order to investigate the pharmacological mechanism of Aloe vera, the levels of the cytokines, tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 were determined by ELISA at various time points. The increases in the levels of TNF-alpha, IL-1beta, and IL-6 were attenuated by Aloe vera.In vivo administration of Aloe vera also markedly enhanced bacterial clearance. Our findings suggest that Aloe vera could be a potential therapeutic agent for the clinical treatment of sepsis. PMID:19298839

  4. Aloe-emodin-induced apoptosis in human gastric carcinoma cells.

    Science.gov (United States)

    Chen, Sheng-Hsuan; Lin, Kai-Yuan; Chang, Chun-Chao; Fang, Chia-Lang; Lin, Chih-Ping

    2007-11-01

    The purpose of this study was to investigate the anticancer effect of aloe-emodin, an anthraquinone compound present in the leaves of Aloe vera, on two distinct human gastric carcinoma cell lines, AGS and NCI-N87. We demonstrate that aloe-emodin induced cell death in a dose- and time-dependent manner. Noteworthy is that the AGS cells were generally more sensitive than the NCI-N87 cells. Aloe-emodin caused the release of apoptosis-inducing factor and cytochrome c from mitochondria, followed by the activation of caspase-3, leading to nuclear shrinkage and apoptosis. In addition, exposure to aloe-emodin suppressed the casein kinase II activity in a time-dependent manner and was accompanied by a reduced phosphorylation of Bid, a downstream substrate of casein kinase II and a pro-apoptotic molecule. These preclinical studies suggest that aloe-emodin represents a suitable and novel chemotherapeutic drug candidate for the treatment of human gastric carcinoma. PMID:17637488

  5. Three dosimetry models of lipoma arborescens treated by {sup 90}Y synovectomy

    Energy Technology Data Exchange (ETDEWEB)

    O’Doherty, Jim, E-mail: jim.odoherty@kcl.ac.uk [Department of Medical Physics-Nuclear Medicine, Royal Surrey County Hospital, Guildford GU2 7XX, United Kingdom and Division of Imaging Sciences, PET Imaging Centre at St. Thomas’ Hospital, King' s College London, London SE1 7EH (United Kingdom); Clauss, Ralf [Department of Nuclear Medicine, Royal Surrey County Hospital, Guildford GU2 7XX (United Kingdom); Scuffham, James [Department of Medical Physics-Nuclear Medicine, Royal Surrey County Hospital, Guildford GU2 7XX (United Kingdom); Khan, Aman [Department of Rheumatology, Royal Surrey County Hospital, Guildford GU2 7XX (United Kingdom); Petitguillaume, Alice; Desbrée, Aurélie [Service de Dosimétrie Interne, Institut de Radioprotection et de Sûreté Nucléaire, 92260 Fontenay-aux-Roses (France)

    2014-05-15

    Purpose: Lipoma arborescens (LA) is a benign intra-articular lipomatous proliferation of the synovial membrane. This extremely rare condition has previously been treated by intra-articular{sup 90}Y radiosynoviorthesis but dosimetry literature on this form of radionuclide therapy is nonexistent. The authors detail methodology for successful treatment of LA and provide for the first time estimates of radiation dosimetry. The authors also analyze the biodistribution of the radiopharmaceutical over the course of the patient's treatment through sequential imaging. Methods: A patient with bilateral LA underwent intracavity injection of{sup 90}Y citrate colloid to the right and left knee joint spaces (181 and 198 MBq, respectively). SPECT/CT datasets were acquired over 9 days to quantify the biodistribution and kinetics of the radiopharmaceutical. Radiation dosimetry was performed using the MIRD schema (through OLINDA software), a custom voxel-based method, and a direct Monte Carlo calculation (OEDIPE). Results: Follow-up MRI showed marked reduction in LA size in both knees. Mean absorbed doses to the LA were 21.2 ± 0.8 and 42.9 ± 2.3 Gy using OLINDA, 8.1 ± 0.3 and 16.7 ± 0.5 Gy using voxel based methodology, and 8.2 ± 0.3 and 15.7 ± 0.5 Gy for OEDIPE in the right and left LA, respectively. Distribution of the radiopharmaceutical within the joint space alters over the imaging period, with less than 1% of the remaining activity having moved posteriorly in the knee cavity. No uptake was detected outside of the joint space after assessment with whole-body scintigraphy. Conclusions: An activity of approximately 185 MBq successfully relieved clinical symptoms of LA. There was good correlation between direct Monte Carlo and voxel based techniques, but OLINDA was shown to overestimate the absorbed dose to the tumor. Accurate dosimetry may help select an activity more tailored to the specific size and location of the LA.

  6. Relationship Between Leaf Structure and Aloin Content in Six Species of Aloe L.%六种芦荟叶的解剖结构及其与芦荟素含量的相关性

    Institute of Scientific and Technical Information of China (English)

    李景原; 王太霞; 沈宗根; 胡正海

    2003-01-01

    The leaf structure, content and the storage location of aloin in the leaves of six species of Aloe L. were studied by means of semi-thin section, high performance liquid chromatography (HPLC) and fluorescent microscope. Results showed that all leaves consisted of epidermis, chlorenchyma, aquiferous tissue and vascular bundles. The leaves had the xeromorphic characteristics, including thickened epidermal cell wall, thickened cuticle, sunken stomata and well-developed aquiferous tissue. With the exception of this, there were remarkable differences in leaf structure among the six species. The chlorenchyma cells were similar to palisade tissues in Aloe arborescens Mill. and A. mutabilis Pillans, but isodiametric in A. vera L., A. vera L. var. chinensis Berg., A. saponaria Hawer and A. greenii Bak. A. arborescens, A. mutabilis, A. vera and A. vera var. chinensis included large parenchymatous cells at the vascular bundles, whereas no such cells were observed at the vascular bundles of A. saponaria and A. greenii. In A. arborescens, A. mutabilis and A. vera, the aquiferous tissue sheaths were present and composed of a layer of small parenchymatous cells without chloroplasts around the aquiferous tissue. While there were no aquiferous tissue sheaths in A. vera var. chinensis, A. saponaria and A. greenii. The HPLC revealed that the content of aloin was high in A. arborescens, low in A. vera, and very low in A. saponaria among the six species. The fluorescent microscopy showed that the yellow-green globule only appeared in the large parenchymatous cells of vascular bundles, vascular bundle sheath and aquiferous tissue sheath, but not in the chlorenchyma and aquiferous tissue. Consequently, the large parenchymatous cells of vascular bundles, vascular bundle sheath and aquiferous tissue sheath were the storage location of aloin. They were positively correlated with the content of aloin.%应用半薄切片法、高效液相色谱法(HPLC)和荧光显微镜研究了6种芦荟

  7. A Tragedy of a Common Man in Arthur Miller's Death of a Salesman

    Institute of Scientific and Technical Information of China (English)

    梁花

    2009-01-01

    @@ 1. Arthur Miller and Death of a Salesman 1.1 Arthur Miller,One of the Greatest American Playwrights of the Twentieth Century Arthur Miller was one of the most preeminent playwrights of the twentieth century and one of America's most distinguished men of letters.He was born in October of 1915 in New York City. His plays continued the realistic tradition that began in the United States in the period between the two World Wars.

  8. Character Contrast in Arthur Miller's Death of a Salesman

    Institute of Scientific and Technical Information of China (English)

    程欣

    2007-01-01

      "I regard the theater as a serious business,one that makes or should make man more human,which is to say,less alone."A great playwright of social philosophy,Arthur Miller advocares that the common man,and none of rank,is the tragic hero of modern times.His plays have always revealed before the public eyes the tragedy of the average American life,the psychology of the ordinary people,and their conflicts with the morality of society.……

  9. Modigliani-Miller, Basel 3 and CRD 4

    DEFF Research Database (Denmark)

    Balling, Morten

    2015-01-01

    Since 2007, bank capital regulation has been strengthened in Europe and globally. Bank organizations have expressed serious concerns about the impact of higher capital requirements on bank funding costs adn on the lending capacity of banks. The message of a 1958-Article by Modigliani and Miller...... is that bankers should not worry. Changes in the debt-equity ratio do not affect the firm's average cost of capital. With reference to a sample of recent empirical studies, this SUERF Policy Note concludes that the thougher and more complex capital regulation requires modification but not rejection of the M...

  10. A Case of Neuromyelitis Optica Masquerading as Miller Fisher Syndrome

    Directory of Open Access Journals (Sweden)

    Yuka Furutani

    2014-10-01

    Full Text Available A 22-year-old woman presented with double vision that she had experienced since an infection 2 weeks previously. A neurological examination showed limited bilateral eye abduction, mimicking Miller Fisher syndrome. However, T2-weighted magnetic resonance imaging of her brain revealed hyperintense areas in the tegmentum of the pons, including the abducens nucleus, and her serum anti-aquaporin-4 antibody test was positive. She was finally diagnosed with neuromyelitis optica. Intravenous high-dose steroid therapy immediately improved the patient's abduction palsy, but bilateral optic neuritis manifested during the treatment. Subsequent treatment with plasma exchange improved her optic neuritis symptoms.

  11. Concentrations of Uranium Isotopes in Uranium Millers' and Miners' Tissues

    OpenAIRE

    United States Nuclear Regulatory Commission

    1985-01-01

    The alpha-emitting isotopes of uranium and thorium were determined in the lungs of 14 former uranium miners and in soft tissues and bones of three miners and two millers. These radionuclides were also determined in soft tissues and bones of seven normal controls. The average concentrations in pCi/kg wet weight in 17 former miners' lungs are as follows: U-238, 75; U-234, 80; Th-230, 79. Concentrations of each nuclide ranged from 2 to 325 pCi/kg. The average ratio of U-238/U-234 ws 0.92, r...

  12. 芦荟维管束的结构与芦荟素积累的相关性%Correlation between the structure of vascular bundle and the content of aloin in Aloe

    Institute of Scientific and Technical Information of China (English)

    王太霞; 李景原; 胡正海

    2003-01-01

    应用半薄切片、组织化学、荧光显微镜观察和薄层层析(TLC)相结合的方法研究了中华芦荟(Aloe vera L. var.chinensis)、木立芦荟(Aloe arborescens)叶和茎内维管束的结构及其与芦荟素积累的关系.结果表明,木立芦荟叶内维管束和中华芦荟叶内外轮的维管束中有大型韧皮薄壁细胞,而木立芦荟茎和中华芦荟叶中内轮维管束无大型韧皮薄壁细胞.组织化学结果表明,用醋酸铅处理过的上述材料,大型韧皮薄壁细胞内出现沉淀物;在荧光显微镜下经蓝光激发,大型韧皮薄壁细胞发出桔黄色荧光,都显示出芦荟素反应.薄层层析(TLC)结果证明,木立芦荟和中华芦荟叶含有大型韧皮薄壁细胞的维管束都含芦荟素,而木立芦荟茎及中华芦荟叶中内轮维管束都不含芦荟素.为此,维管束中的大型韧皮薄壁细胞与芦荟素的积累密切相关,维管束中是否有大型韧皮薄壁细胞可作为判断是否含有芦荟素的解剖学指标.

  13. Modulation of drug efflux by aloe materials: An In Vitro investigation across rat intestinal tissue

    OpenAIRE

    Beneke Carien; Viljoen Alvaro; Hamman Josias

    2013-01-01

    Background: Clinically, significant herb-drug interactions have been previously documented and can be pharmacodynamic and/or pharmacokinetic in nature. Pharmacokinetic interactions have been attributed to induction or inhibition of either metabolic enzymes or efflux transporters. Objective: The effect of gel and whole leaf materials from 3 different aloe species namely Aloe ferox, Aloe marlothii, and Aloe vera as well as polysaccharides precipitated from the A. vera materials o...

  14. Formulation and Characterization of Aceclofenac -Aloe vera Transemulgel.

    Science.gov (United States)

    Raju, Y Prasanna; Haritha, K; Satyanarayana, Rao P; Vandana, K R; Bindu, D Thushara; Vinesha, V; Chowdary, V Harini

    2015-01-01

    The present research was aimed to formulate aceclofenac transemulgel using Aloe vera as gel base. The prepared formulations were subjected to physical characterization, in-vitro and in-vivo assessment. Aceclofenac, a hydrophobic potential non steroidal anti inflammatory drug, causes ulceration upon chronic oral administration, could be formulated into transemulgel to enhance therapeutic efficacy and to lower the unwanted side effects. The transemulgel was prepared from aqueous Aloe vera gel and aceclofenac emulsion. The prepared transemulgel was evaluated for its pH, viscosity, drug content, skin irritation, in-vitro diffusion and accelerated stability studies. The prepared aceclofenac-Aloe vera tranemulgel and commercial aceclofenac gel were subjected to pharmacodynamic studies in albino rats of Wistar strain employing carrageenan induced left hind paw edema method to assess the anti-inflammatory effect. The transemulgel showed a pH of 6.78 and viscosity of 18 cps. In-vitro diffusion data revealed better permeation characteristics. Topical application of formulation found no skin irritation. Stability study has proved the integrity of the formulation. The prepared aceclofenac Aloe vera transemulgel showed better in-vitro drug release when compared with the commercial aceclofenac gel formulation. Anti-inflammatory activity in treated rats showed the significant paw volume reduction at pAloe vera as gel base.

  15. Formulation and Characterization of Aceclofenac -Aloe vera Transemulgel.

    Science.gov (United States)

    Raju, Y Prasanna; Haritha, K; Satyanarayana, Rao P; Vandana, K R; Bindu, D Thushara; Vinesha, V; Chowdary, V Harini

    2015-01-01

    The present research was aimed to formulate aceclofenac transemulgel using Aloe vera as gel base. The prepared formulations were subjected to physical characterization, in-vitro and in-vivo assessment. Aceclofenac, a hydrophobic potential non steroidal anti inflammatory drug, causes ulceration upon chronic oral administration, could be formulated into transemulgel to enhance therapeutic efficacy and to lower the unwanted side effects. The transemulgel was prepared from aqueous Aloe vera gel and aceclofenac emulsion. The prepared transemulgel was evaluated for its pH, viscosity, drug content, skin irritation, in-vitro diffusion and accelerated stability studies. The prepared aceclofenac-Aloe vera tranemulgel and commercial aceclofenac gel were subjected to pharmacodynamic studies in albino rats of Wistar strain employing carrageenan induced left hind paw edema method to assess the anti-inflammatory effect. The transemulgel showed a pH of 6.78 and viscosity of 18 cps. In-vitro diffusion data revealed better permeation characteristics. Topical application of formulation found no skin irritation. Stability study has proved the integrity of the formulation. The prepared aceclofenac Aloe vera transemulgel showed better in-vitro drug release when compared with the commercial aceclofenac gel formulation. Anti-inflammatory activity in treated rats showed the significant paw volume reduction at pAloe vera as gel base. PMID:25751659

  16. ANTIMICROBIAL ACTIVITY OF ALOE VERA LEAF EXTRACT

    Directory of Open Access Journals (Sweden)

    Kedarnath

    2013-12-01

    Full Text Available The antimicrobial activity of aloe vera extract was tested against pathogenic bacteria like Staphylococcus aureus, Klebisella pneumonia and E.coli and fungi like Aspergillus niger and Candida at a dose of 1:20 mg/ml and 2:40 mg/ml by using cup plate diffusion method. Various solvents such as petroleum ether, chloroform and methanol were used for extracts. The results reveal that, methanol and petroleum ether at a dose of 20 mg/ml has showed significant activity against Klebisella pneumonia and E.coli whereas in fungi, methanol extract showed significant activity against Aspergillus niger and Candida. Methanol extract has showed maximum inhibitory activity against E.coli and Candida. Petroleum ether has showed moderate inhibitory activity against Klebisella pneumonia and Candida. The zone of inhibition was measured and compared with standard Gentamycin (1 mg/ml. However, in none of the above mentioned extracts the inhibition zone was not more than that found in standard i.e., Gentamycin.

  17. Hemlock alkaloids from Socrates to poison aloes.

    Science.gov (United States)

    Reynolds, Tom

    2005-06-01

    Hemlock (Conium maculatum L. Umbelliferae) has long been known as a poisonous plant. Toxicity is due to a group of piperidine alkaloids of which the representative members are coniine and gamma-coniceine. The latter is the more toxic and is the first formed biosynthetically. Its levels in relation to coniine vary widely according to environmental conditions and to provenance of the plants. Surprisingly, these piperidine alkaloids have turned up in quite unrelated species in the monocotyledons as well as the dicotyledons. Aloes, for instance, important medicinal plants, are not regarded as poisonous although some species are very bitter. Nevertheless a small number of mostly local species contain the alkaloids, especially gamma-coniceine and there have been records of human poisoning. The compounds are recognized by their characteristic mousy smell. Both acute and chronic symptoms have been described. The compounds are neurotoxins and death results from respiratory failure, recalling the effects of curare. Chronic non-lethal ingestion by pregnant livestock leads to foetal malformation. Both acute and chronic toxicity are seen with stock in damp meadows and have been recorded as problems especially in North America. The alkaloids derive biosynthetically from acetate units via the polyketide pathway in contrast to other piperidine alkaloids which derive from lysine.

  18. Amending Miller's Pyramid to Include Professional Identity Formation.

    Science.gov (United States)

    Cruess, Richard L; Cruess, Sylvia R; Steinert, Yvonne

    2016-02-01

    In 1990, George Miller published an article entitled "The Assessment of Clinical Skills/Competence/Performance" that had an immediate and lasting impact on medical education. In his classic article, he stated that no single method of assessment could encompass the intricacies and complexities of medical practice. To provide a structured approach to the assessment of medical competence, he proposed a pyramidal structure with four levels, each of which required specific methods of assessment. As is well known, the layers are "Knows," "Knows How," "Shows How," and "Does." Miller's pyramid has guided assessment since its introduction; it has also been used to assist in the assessment of professionalism.The recent emphasis on professional identity formation has raised questions about the appropriateness of "Does" as the highest level of aspiration. It is believed that a more reliable indicator of professional behavior is the incorporation of the values and attitudes of the professional into the identity of the aspiring physician. It is therefore proposed that a fifth level be added at the apex of the pyramid. This level, reflecting the presence of a professional identity, should be "Is," and methods of assessing progress toward a professional identity and the nature of the identity in formation should be guided by currently available methods.

  19. Comparative performance of ALOS PALSAR polarization bands and its combination with ALOS AVNIR-2 data for land cover classification

    Science.gov (United States)

    Sim, C. K.; Abdullah, K.; MatJafri, M. Z.; Lim, H. S.

    2014-02-01

    Microwave Remote Sensing data have been widely used for land cover classification in our environment. In this study, ALOS PALSAR polarization bands were used to identify land cover features in three study areas in Malaysia. The study area consists of Penang, Perak and Kedah. The aims of this research are to investigate the performance of ALOS PALSAR datasets which are assessed independently and combination of these data with ALOS AVNIR-2 for land cover classification. Standard supervised classification method Maximum Likelihood Classifier (MLC) was applied. Various land cover classes were identified and assessed using the Transformed Divergence (TD) separability measures. The PALSAR data training areas were chosen based on the information obtained from ALOS AVNIR-2 datasets. The original data gave very poor results in identifying land cover classes due to the presence of immense speckle. The extraction and use of mean texture measures was found to be very advantageous when evaluating the separability among the different land covers. Hence, mean texture was capable to provide higher classification accuracies as compared to the original radar. The highest overall accuracy was achieved by combining the radar mean texture with ALOS AVNIR-2 data. This study proved that the land cover of Penang, Perak, and Kedah can be mapped accurately using combination of optical and radar data.

  20. Comparative performance of ALOS PALSAR polarization bands and its combination with ALOS AVNIR-2 data for land cover classification

    International Nuclear Information System (INIS)

    Microwave Remote Sensing data have been widely used for land cover classification in our environment. In this study, ALOS PALSAR polarization bands were used to identify land cover features in three study areas in Malaysia. The study area consists of Penang, Perak and Kedah. The aims of this research are to investigate the performance of ALOS PALSAR datasets which are assessed independently and combination of these data with ALOS AVNIR-2 for land cover classification. Standard supervised classification method Maximum Likelihood Classifier (MLC) was applied. Various land cover classes were identified and assessed using the Transformed Divergence (TD) separability measures. The PALSAR data training areas were chosen based on the information obtained from ALOS AVNIR-2 datasets. The original data gave very poor results in identifying land cover classes due to the presence of immense speckle. The extraction and use of mean texture measures was found to be very advantageous when evaluating the separability among the different land covers. Hence, mean texture was capable to provide higher classification accuracies as compared to the original radar. The highest overall accuracy was achieved by combining the radar mean texture with ALOS AVNIR-2 data. This study proved that the land cover of Penang, Perak, and Kedah can be mapped accurately using combination of optical and radar data

  1. Disaster monitoring by ALOS and follow-on mission

    Science.gov (United States)

    Moriyama, Takashi

    2006-12-01

    Advanced Land Observing Satellite(ALOS) was successfuly launched on January 24th 2006 at Tanegashima Space Center by H-IIA rocket. The Satellite mass is about 4 tons of weight, Sun synchronous sub-recurrent orbit, repetation cycle is 46 days (sub cycle 2days) and 5 years mission operation. ALOS has four missions such as Cartography, Regional Observation, Resource Survey and Diasater monitoring. After the satelllite launch, there were several opportunities to observe natural disasters in the world.. ALOS will be distribute disaster information through international framework such as Sentinel Asia and International Charter on Disaster Monitoring. The 'Sentinel Asia' initiative was established by space agencies and disaster authorities in the Asia and Oceania, to use Remote Sensing information and Web-GIS data-delivery technologies in support of disaster management in the Asia-Pacific region. Sentinel Asia is 'voluntary and best-efforts-basis initiatives' led by the Asia-Pacific Regional Space Agency Forum (APRSAF) to share the disaster information in the region using the 'Digital Asia' (Web-GIS) platform. International Charter is the membership framework to operate the satellite in case of disaster occurs. and distribute the data and information free of charge. ALOS is nominated both activities to contribute disaster monitoring and mitigation. This paper describes the introduction of ALOS and acquired disaster images to indicate its potential use for disaster monitoring. The design of follow on mission is indispensable to promise continuous monitoring of natural disaster. This paper also describes the initial idea of ALOS follow on mission.

  2. Pengeringan Lidah Buaya (AloVera) Menggunakan Oven Gelombang Mikro (Microwave Oven)

    OpenAIRE

    Edy Hartulistiyoso; Rokhani Hasbullah; Eka Priyana

    2011-01-01

    Aloe vera (Aloe vera) is known as a useful plant, both as food, cosmetics or pharmaceuticals. Due its high water content, Aloe vera should be processed immediately after harvest. This paper will discuss the drying of aloe vera using microwave oven. The drying process of 50 gr Aloe vera gel and rind using 80 Watts microwave power completed in 140 minutes to reach the final moisture content of 7% wet basis. The drying process in microwave drying shows similar process to that of conventiona...

  3. Plan de negocios de yogur con aloe vera

    OpenAIRE

    Cianchelli Agra, María Florencia

    2008-01-01

    Desarrollo de un plan de negocios para un producto nuevo: “Yogurt a base de aloe vera”. Se considera importante la investigación del problema propuesto por que, se sustenta el éxito o el fracaso de un nuevo producto lácteo antes de ser lanzado al mercado. Debido a esto, se plantea el desarrollo de una prueba piloto para beneficiar a la empresa antes de realizar una inversión de tan grande magnitud. Además, con los ingredientes del producto (aloe vera) permite que se fortalezca la regulariz...

  4. Darbuotojo sveikatai padarytos žalos atlyginimas: teisiniai aspektai

    OpenAIRE

    Verikas, Andrius

    2008-01-01

    Darbuotojo sveikatai padarytos žalos atlyginimo garantijos yra susijusios ne tik su darbdavio pareigos sudaryti darbuotojams saugias ir sveikas darbo sąlygas pažeidimu ir jo materialine atsakomybe, bet ir visuomenės interesu garantuoti socialinę apsaugą žalą sveikatai patyrusiems asmenims. Darbuotojo sveikatai padaryta žala atlyginama taikant darbdavio materialinę atsakomybę ir nelaimingų atsitikimų darbe ir profesinių ligų socialinio draudimo kompensacijas. Šie žalos kompensavimo būdai turėt...

  5. ALOE VERA: A REVIEW OF ITS CLINICAL EFFECTIVENESS

    Directory of Open Access Journals (Sweden)

    Malik Itrat

    2013-08-01

    Full Text Available Aloe vera has been used for over five thousand years. Throughout history, it has been considered a magical plant, almost a panacea, capable of remedying many of mankind’s ailments. It is only in the last 20 years, after a series of proven research, that we can highlight the characteristics of this plant, whose secrets have been hidden behind a blanket of botanical and pharmacological puzzles that only today begin to yield some answers. The Aloe vera plant and its clinical uses are briefly reviewed in this article.

  6. STUDIES ON THE EFFICACY OF ALOE VERA ON ANTIMICROBIAL ACTIVITY

    Directory of Open Access Journals (Sweden)

    T. Karpagam

    2011-04-01

    Full Text Available The aqueous, ethanolic, methanolic, petroleum ether and acetone extracts of Aloe vera were screened for anti-microbial activity using the Minimal Inhibitory Concentration (MIC method. They were tested against five bacteria (Escherischia coli, Pseudomonas aeruginosa, Bacillus subtilis, Klebsiella pneumonia and Staphylococcus aureus. The susceptibility of the microorganisms to the extracts in different concentrations plants were compared. The active component in the extract was determined using HPLC technique. The main aim of this study was to find anti- microbial activity of Aloe vera and to find the presence of active compounds present for the treatment of disease caused by pathogenic microorganism .

  7. A planta medicinal Aloe Vera na indústria alimentar

    OpenAIRE

    Manuel, Valentina Yolanda Lemos de Lucas

    2011-01-01

    A planta Aloe é uma erva importante vastamente utilizada na medicina tradicional. Entre estas, a Aloe vera é considerada a espécie biologicamente mais activa e é também a espécie mais comercializada. Vários estudos revelaram que os compostos das suas folhas possuem actividade terapeutica. Da folha desta planta são obtidos o látex e o gel. O látex conhecido pelas suas propriedades laxativas. O gel consiste em cerca de 99.5% de água, os restantes 0.5 – 1% de material sólido (vitaminas hidro e l...

  8. Maslow and Miller: An Exploration of Gender and Affiliation in the Journey to Competence

    Science.gov (United States)

    Coy, Doris Rhea; Kovacs-Long, Judith

    2005-01-01

    This article shows that although neither Abraham Maslow nor Jean Baker Miller reference each other in their writings, they are following different paths to the same conclusion: competence proceeds from connection. Miller and Maslow both describe a developmental model that applies equally to women and men. The conclusion of the authors of this…

  9. 33 CFR 110.79b - Millers Bay, Lake Winnebago, Oshkosh, WI

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Millers Bay, Lake Winnebago, Oshkosh, WI 110.79b Section 110.79b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND..., Oshkosh, WI The area adjacent to Menominee Park in Millers Bay within the following boundaries:...

  10. Karp-Miller Trees for a Branching Extension of VASS

    Directory of Open Access Journals (Sweden)

    Kumar Neeraj Verma

    2005-12-01

    Full Text Available We study BVASS (Branching VASS which extend VASS (Vector Addition Systems with States by allowing addition transitions that merge two configurations. Runs in BVASS are tree-like structures instead of linear ones as for VASS. We show that the construction of Karp-Miller trees for VASS can be extended to BVASS. This entails that the coverability set for BVASS is computable. This allows us to obtain decidability results for certain classes of equational tree automata with an associative-commutative symbol. Recent independent work by de Groote et al. implies that decidability of reachability in BVASS is equivalent to decidability of provability in MELL (multiplicative exponential linear logic, which is still an open problem. Hence our results are also a step towards answering this question in the affirmative.

  11. Biofunctional properties of Eruca sativa Miller (rocket salad) hydroalcoholic extract.

    Science.gov (United States)

    Sultan, Khushbakht; Zakir, Muhammad; Khan, Haroon; Rauf, Abdur; Akber, Noor Ul; Khan, Murad Ali

    2016-01-01

    Eruca sativa Miller is a worldwide common alimentary plant (rocket leaves). The aim of this study was to correlate the potential in vitro scavenging activity of the E. sativa hydroalcoholic extract (HAE) with its in vivo hypoglycaemic effect. In DDPH free radical (DFR) and ferric-reducing antioxidant power assays, HAE in a concentration dependent manner (25-100 μg/mL) displayed a strong scavenging activity with maximum effect of 88% and 75% at 100 μg/mL, respectively. Daily administration of HAE (50 mg/kg; p.o.) in the in vivo model of alloxan-induced diabetic rabbits for 28 days showed significant reduction in glycaemia, also supported by recovery of body weight. In conclusion, our results give preliminary information on the potential use of this plant as a nutraceutical, useful to control and/or prevent a hyperglycaemic status.

  12. Pollen Morphology of Acinos Miller Species Growing in Turkey

    Institute of Scientific and Technical Information of China (English)

    Ayla Kaya; Hatice Kutluk

    2007-01-01

    The pollen morphology of six taxa of the genus Acinos Miller has been examined under scanning electron microscopy(SEM) and a description of each taxon has been given. Acinos pollen is stephanocolpate (hexacolpate). Two main exine sculpturing types, foveolate-reticulate (only in subspecies of A. troodi) and reticulate have been defined. The dimension for the polar length ranges between 25.8-47.4 μm, equatorial width 24.5-34.4 μm, colpus length 20.0-40.5 μm and colpus width 1.2-2.5 μm. The shape is mostly subprolate to prolate, seldomly prolate-spheroidal. The results reveal rather uniform morphological features, however fine details are characteristic to differentiate the pollen taxa. Acinos pollen also share some common morphological features with the other Lamiaceae pollen.

  13. Adaptation: a contemporary view, revisiting Crichton-Miller's 1925 paper.

    Science.gov (United States)

    Music, Graham

    2016-03-01

    In this paper I discuss a contemporary 'take' on the concept of adaptation in light of Crichton-Miller's original 1926 paper. I look briefly at some of the ways that contemporary thinking is both similar to and different from ideas of 90 years ago. In particular I think about how recent neurobiological findings, epigenetic research and attachment theory have cast new light on our understanding of the ways humans adapt to social and emotional environments. It looks at how psychiatric presentations which are seen as maladaptive might well have an adaptive origin in early life. In this account I emphasise how a more modern version of evolutionary theory can be developed, particularly one influenced by life history theory, and suggest that such ideas have powerful explanatory power as well as being based solidly in good research. PMID:26908879

  14. Aloe vera extract functionalized zinc oxide nanoparticles as nanoantibiotics against multi-drug resistant clinical bacterial isolates.

    Science.gov (United States)

    Ali, Khursheed; Dwivedi, Sourabh; Azam, Ameer; Saquib, Quaiser; Al-Said, Mansour S; Alkhedhairy, Abdulaziz A; Musarrat, Javed

    2016-06-15

    ZnO nanoparticles (ZnONPs) were synthesised through a simple and efficient biogenic synthesis approach, exploiting the reducing and capping potential of Aloe barbadensis Miller (A. vera) leaf extract (ALE). ALE-capped ZnO nanoparticles (ALE-ZnONPs) were characterized using UV-Vis spectroscopy, X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), and transmission electron microscopy (TEM) analyses. XRD analysis provided the average size of ZnONPs as 15 nm. FTIR spectral analysis suggested the role of phenolic compounds, terpenoids and proteins present in ALE, in nucleation and stability of ZnONPs. Flow cytometry and atomic absorption spectrophotometry (AAS) data analyses revealed the surface binding and internalization of ZnONPs in Gram +ve (Staphylococcus aureus) and Gram -ve (Escherichia coli) cells, respectively. Significant antibacterial activity of ALE-ZnONPs was observed against extended spectrum beta lactamases (ESBL) positive E. coli, Pseudomonas aeruginosa, and methicillin resistant S. aureus (MRSA) clinical isolates exhibiting the MIC and MBC values of 2200, 2400 μg/ml and 2300, 2700 μg/ml, respectively. Substantial inhibitory effects of ALE-ZnONPs on bacterial growth kinetics, exopolysaccharides and biofilm formation, unequivocally suggested the antibiotic and anti-biofilm potential. Overall, the results elucidated a rapid, environmentally benign, cost-effective, and convenient method for ALE-ZnONPs synthesis, for possible applications as nanoantibiotics or drug carriers. PMID:27031596

  15. Immunomodulatory properties of aloe vera gel in mice

    Directory of Open Access Journals (Sweden)

    Madan Jyotsana

    2008-01-01

    Full Text Available Administration of Aloe vera extract to swiss albino mice (300 mg/kg i.p. daily for five days, significantly (P < 0.01 increases the total white blood cells count. Further, it increases humoral immune response, as demonstrated from the increase in plaque-forming cells in the spleen and circulating antibody titre.

  16. Evidence of the gastroprotective and anti-Helicobacter pylori activities of β-mangostin isolated from Cratoxylum arborescens (vahl blume

    Directory of Open Access Journals (Sweden)

    Sidahmed HMA

    2016-01-01

    Full Text Available Heyam Mohamed Ali Sidahmed,1 Najihah Mohd Hashim,1 Syam Mohan,2 Siddig Ibrahim Abdelwahab,2 Manal Mohamed Elhassan Taha,2 Firouzeh Dehghan,3 Maizatulakmal Yahayu,4 Gwendoline Cheng Lian Ee,5 Mun Fai Loke,6 Jamuna Vadivelu6 1Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; 2Medical Research Center, Jazan University, Jazan, Saudi Arabia; 3Department of Exercise Science, Sports Centre, University of Malaya, Kuala Lumpur, 4Department of Bioproduct Research and Innovation, Institute of Bioproduct Development (IBD, Universiti Teknologi Malaysia (UTM, Johor Bahru, 5Department of Chemistry, Faculty of Science, Universiti Putra Malaysia (UPM, Serdang, 6Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia Purpose: β-Mangostin (BM from Cratoxylum arborescens demonstrated various pharmacological activities such as anticancer and anti-inflammatory. In this study, we aimed to investigate its antiulcer activity against ethanol ulcer model in rats. Materials and methods: BM was isolated from C. arborescens. Gastric acid output, ulcer index, gross evaluation, mucus production, histological evaluation using hematoxylin and eosin and periodic acid–Schiff staining and immunohistochemical localization for heat shock protein 70 (HSP70 and Bax proteins were investigated. Possible involvement of reduced glutathione, lipid peroxidation, prostaglandin E2, antioxidant enzymes, superoxide dismutase and catalase enzymes, radical scavenging, nonprotein sulfhydryl compounds, and anti-Helicobacter pylori were investigated. Results: BM showed antisecretory activity against the pylorus ligature model. The pretreatment with BM protect gastric mucosa from ethanol damaging effect as seen by the improved gross and histological appearance. BM significantly reduced the ulcer area formation, the submucosal edema, and the leukocytes infiltration compared to the ulcer control. The compound

  17. Excavating the Role of Aloe Vera Wrapped Mesoporous Hydroxyapatite Frame Ornamentation in Newly Architectured Polyurethane Scaffolds for Osteogenesis and Guided Bone Regeneration with Microbial Protection.

    Science.gov (United States)

    Selvakumar, M; Pawar, Harpreet Singh; Francis, Nimmy K; Das, Bodhisatwa; Dhara, Santanu; Chattopadhyay, Santanu

    2016-03-01

    Guided bone regeneration (GBR) scaffolds are unsuccessful in many clinical applications due to a high incidence of postoperative infection. The objective of this work is to fabricate GBR with an anti-infective electrospun scaffold by ornamenting segmented polyurethane (SPU) with two-dimensional Aloe vera wrapped mesoporous hydroxyapatite (Al-mHA) nanorods. The antimicrobial characteristic of the scaffold has been retrieved from the prepared Al-mHA frame with high aspect ratio (∼14.2) via biosynthesis route using Aloe vera (Aloe barbadensis miller) extract. The Al-mHA frame was introduced into an unprecedented SPU matrix (solution polymerized) based on combinatorial soft segments of poly(ε-caprolactone) (PCL), poly(ethylene carbonate) (PEC), and poly(dimethylsiloxane) (PDMS), by an in situ technique followed by electrospinning to fabricate scaffolds. For comparison, pristine mHA nanorods are also ornamented into it. An enzymatic ring-opening polymerization technique was adapted to synthesize soft segment of (PCL-PEC-b-PDMS). Structure elucidation of the synthesized polymers is established by nuclear magnetic resonance spectroscopy. Sparingly, Al-mHA ornamented scaffolds exhibit tremendous improvement (175%) in the mechanical properties with promising antimicrobial activity against various human pathogens. After confirmation of high osteoconductivity, improved biodegradation, and excellent biocompatibility against osteoblast-like MG63 cells (in vitro), the scaffolds were implanted in rabbits as an animal model by subcutaneous and intraosseous (tibial) sites. Improved in vivo biocompatibilities, biodegradation, osteoconductivity, and the ability to provide an adequate biomimetic environment for biomineralization for GBR of the scaffolds (SPU and ornamented SPUs) have been found from the various histological sections. Early cartilage formation, endochondral ossification, and rapid bone healing at 4 weeks were found in the defects filled with Al-mHA ornamented

  18. Excavating the Role of Aloe Vera Wrapped Mesoporous Hydroxyapatite Frame Ornamentation in Newly Architectured Polyurethane Scaffolds for Osteogenesis and Guided Bone Regeneration with Microbial Protection.

    Science.gov (United States)

    Selvakumar, M; Pawar, Harpreet Singh; Francis, Nimmy K; Das, Bodhisatwa; Dhara, Santanu; Chattopadhyay, Santanu

    2016-03-01

    Guided bone regeneration (GBR) scaffolds are unsuccessful in many clinical applications due to a high incidence of postoperative infection. The objective of this work is to fabricate GBR with an anti-infective electrospun scaffold by ornamenting segmented polyurethane (SPU) with two-dimensional Aloe vera wrapped mesoporous hydroxyapatite (Al-mHA) nanorods. The antimicrobial characteristic of the scaffold has been retrieved from the prepared Al-mHA frame with high aspect ratio (∼14.2) via biosynthesis route using Aloe vera (Aloe barbadensis miller) extract. The Al-mHA frame was introduced into an unprecedented SPU matrix (solution polymerized) based on combinatorial soft segments of poly(ε-caprolactone) (PCL), poly(ethylene carbonate) (PEC), and poly(dimethylsiloxane) (PDMS), by an in situ technique followed by electrospinning to fabricate scaffolds. For comparison, pristine mHA nanorods are also ornamented into it. An enzymatic ring-opening polymerization technique was adapted to synthesize soft segment of (PCL-PEC-b-PDMS). Structure elucidation of the synthesized polymers is established by nuclear magnetic resonance spectroscopy. Sparingly, Al-mHA ornamented scaffolds exhibit tremendous improvement (175%) in the mechanical properties with promising antimicrobial activity against various human pathogens. After confirmation of high osteoconductivity, improved biodegradation, and excellent biocompatibility against osteoblast-like MG63 cells (in vitro), the scaffolds were implanted in rabbits as an animal model by subcutaneous and intraosseous (tibial) sites. Improved in vivo biocompatibilities, biodegradation, osteoconductivity, and the ability to provide an adequate biomimetic environment for biomineralization for GBR of the scaffolds (SPU and ornamented SPUs) have been found from the various histological sections. Early cartilage formation, endochondral ossification, and rapid bone healing at 4 weeks were found in the defects filled with Al-mHA ornamented

  19. Efficacy of orally administered powdered aloe juice (Aloe ferox against ticks on cattle and ticks and fleas on dogs

    Directory of Open Access Journals (Sweden)

    J.J. Fourie

    2005-06-01

    Full Text Available The efficacy of orally administered powdered aloe juice (Aloe ferox was evaluated against ticks on cattle and against ticks and fleas on dogs. Twelve calves were each infested over a 25-day period with approximately 4000 larvae of Rhipicephalus (Boophilus decoloratus and allocated to 3 groups of 4 calves each. Three days after the last larval infestation and daily for 22 days thereafter, the calves in 1 group were fed 5 mg / kg body weight and those in another 25 mg / kg body weight of powdered aloe juice incorporated in game maintenance pellets, while the animals in the 3rd group received only pellets. Detached female ticks were collected daily and counted and the weights and the fertility of groups of 50 engorged female ticks collected from the animals were ascertained. The powdered aloe juice in the game maintenance pellets had no effect on the tick burdens of the calves or on the fertility of the ticks. Six dogs, in each of 2 groups, were treated daily for 15 consecutive days, commencing on Day -5 before the 1st tick infestation, with either 0.39 g or 0.74 g of powdered aloe juice, administered orally in gelatin capsules, while a 3rd group of 6 dogs served as untreated controls. All the dogs were challenged with Haemaphysalis leachi on Days 0 and +7, and with Ctenocephalides felis on Days+1and +8, and efficacy assessments were made 1 day after flea and 2 days after tick challenge, respectively. Treatment was not effective against ticks or fleas on the dogs.

  20. SLN as a topical delivery system for Artemisia arborescens essential oil: In vitro antiviral activity and skin permeation study

    Science.gov (United States)

    Lai, Francesco; Sinico, Chiara; De Logu, Alessandro; Zaru, Marco; Müller, Rainer H; Fadda, Anna M

    2007-01-01

    The effect of SLN incorporation on transdermal delivery and in vitro antiherpetic activity of Artemisia arborescens essential oil was investigated. Two different SLN formulations were prepared using the hot – pressure homogenization technique, Compritol 888 ATO as lipid, and Poloxamer 188 and Miranol Ultra C32 as surfactants. Formulations were examined for their stability for two years by monitoring average size distribution and zeta potential values. The antiviral activity of free and SLN incorporated essential oil was tested in vitro against Herpes Simplex Virus-1 (HSV-1) by a quantitative tetrazolium-based colorimetric method (MTT), while the effects of essential oil incorporation into SLN on both the permeation through and the accumulation into the skin strata was investigated by using in vitro diffusion experiments through newborn pig skin and an almond oil Artemisia essential oil solution as a control. Results showed that both SLN formulations were able to entrap the essential oil in high yields and that the mean particle size increased only slightly after two years of storage, indicating a high physical stability. In vitro antiviral assays showed that SLN incorporation did not affect the essential oil antiherpetic activity. The in vitro skin permeation experiments demonstrated the capability of SLN of greatly improving the oil accumulation into the skin, while oil permeation occurred only when the oil was delivered from the control solution. PMID:18019840

  1. SINTESIS MEMBRAN NATA ALOE VERA-ETILENDIAMIN DAN KARAKTERISASINYA

    Directory of Open Access Journals (Sweden)

    EB Susatyo

    2014-06-01

    Full Text Available Serat yang terkandung di dalam nata Aloe vera adalah selulosa sehingga dapat digunakan dalam sintesis membran. Telah dilakukan penelitian tentang sintesis membran nata Aloe vera-etilendiamin (nata-en menggunakan sistem vakum cair. Proses preparasi membran berlangsung melalui tiga tahap, yaitu preparasi nata Aloe vera, aktivasi menggunakan asam sulfat, dan modifikasi dengan menggunakan etilendiamin. Tujuan penelitian adalah untuk mempelajari teknik dalam sintesis membran nata-en kemudian melakukan karakterisasi untuk mengetahui karakter strukturnya. Hasil penelitian menunjukkan perilaku yang berbeda dalam hal sifat mekanik dan strukturnya. Membran nata murni memiliki sifat mekanik yang kuat, nata teraktivasi cenderung rapuh, sedangkan nata-en bersifat liat. Spektra infra merah dari ketiga tipe membran (nata murni, nata teraktivasi, dan nata-en secara umum tidak mengalami perubahan yang signifikan, hanya terjadi pergeseran panjang gelombang dari masing-masing membran. Berdasarkan spektra infra merah dapat diketahui bahwa masing-masing membran mempunyai gugus hidroksil, tetapi serapannya semakin melebar untuk setiap membran. Gugus alkil dan karboksil juga masih tampak, namun pada membran nata teraktivasi serapannya berkurang, sedangkan pada membran nata-en muncul puncak baru yang menunjukkan adanya gugus amin. Hal ini membuktikan bahwa telah terjadi ikatan antara nata dengan etilendiamin. Fibers contained in nata Aloe vera is cellulose that can be used in the synthesis of membrane. The research has done on the synthesis of nata Aloe vera-ethylenediamine (nata-en membrane by using liquid vacuum system. Membrane preparation process consisted of three stages, they are nata Aloe vera preparation, activation using sulfuric acid, and membrane modification by using ethylenediamine. The purpose of research is to study the technique of nata-en membrane synthesis then to perform the characterization to determine the character of their structure.The results

  2. Omphalocele in Miller-Dieker syndrome: Expanding the phenotype

    Energy Technology Data Exchange (ETDEWEB)

    Chitayat, D. [Toronto Hospital-General Division, Ontario (Canada)]|[Univ. of Toronto, Ontario (Canada); Moola, S.; Yarkoni, D. [Toronto Hospital-General Division, Ontario (Canada)] [and others

    1997-03-31

    We report on a patient prenatally diagnosed with omphalocele, mild cerebral ventriculomegaly, nuchal fold thickening, and cystic changes in the umbilical cord who was found postnatally to have lissencephaly type I. Prenatal chromosome analysis showed a normal male karyotype; however, postnatal high resolution banding and FISH analysis, using a probe for locus D17S379 in chromosome region 17p13.3, demonstrated a deletion at 17p13.3 consistent with Miller-Dieker syndrome (MDS). A review documented four more cases with MDS/isolated lissencephaly/17p-, with omphalocele. Because MDS is a contiguous gene disorder, we speculate that a gene or genes in this region have a major role in the closure of the lateral folds or the return of the midgut from the body stalk to the abdomen at 5-11 weeks of gestation. Prenatal diagnosis of omphalocele with mild ventriculomegaly should prompt FISH analysis for a deletion in 17p13.3. 44 refs., 7 figs., 1 tab.

  3. Aanpassing en toetsing van die Rothwell-Miller-belangstellingsvraelys

    Directory of Open Access Journals (Sweden)

    Jacobus G. Maree

    2015-02-01

    Full Text Available Die doel van hierdie studie was om ’n bestaande, maar uiters verouderde belangstellingsvraelys (Rothwell-Miller-belangstellingsvraelys [RMBV] aan te pas. In die eerste fase is vier provinsies by wyse van doelsteekproeftrekking geselekteer: een stedelik en drie plattelands of semiplattelands. In fase twee is ’n steekproef van 518 Graad 11-leerders met behulp van doelsteekproeftrekking geselekteer (gemiddelde ouderdom [x] manlik = 17.52 jaar, vroulik = 17.39 jaar; standaardafwyking [s] manlik = 0.97 jaar, vroulik = 0.93 in agt skole, verdeel volgens onderrigtaal (Afrikaans/Engels en streek (stedelik/plattelands/semiplattelands. Statistiese analises het die vasstelling van betroubaarheid ingesluit by wyse van die berekening van Cronbach se α, asook die halfverdelingsmetode. Die data is verder geanaliseer by wyse van statistiese tegnieke soos t-toetse, ANOVA, asook Tukey se Honest Significant Differencetoets (HSD. Die resultate word bespreek en die gevolgtrekking word gemaak dat hoewel die aangepaste vraelys tot ’n nuttige instrument vir gebruik in Suid-Afrika ontwikkel kan word, verdere navorsing eers nodig is.

  4. Larson-Miller Constant of Heat-Resistant Steel

    Science.gov (United States)

    Tamura, Manabu; Abe, Fujio; Shiba, Kiyoyuki; Sakasegawa, Hideo; Tanigawa, Hiroyasu

    2013-06-01

    Long-term rupture data for 79 types of heat-resistant steels including carbon steel, low-alloy steel, high-alloy steel, austenitic stainless steel, and superalloy were analyzed, and a constant for the Larson-Miller (LM) parameter was obtained in the current study for each material. The calculated LM constant, C, is approximately 20 for heat-resistant steels and alloys except for high-alloy martensitic steels with high creep resistance, for which C ≈ 30 . The apparent activation energy was also calculated, and the LM constant was found to be proportional to the apparent activation energy with a high correlation coefficient, which suggests that the LM constant is a material constant possessing intrinsic physical meaning. The contribution of the entropy change to the LM constant is not small, especially for several martensitic steels with large values of C. Deformation of such martensitic steels should accompany a large entropy change of 10 times the gas constant at least, besides the entropy change due to self-diffusion.

  5. Mathematical modeling on vacuum drying of Zizyphus jujuba Miller slices.

    Science.gov (United States)

    Lee, Jun Ho; Zuo, Li

    2013-02-01

    The thin-layer vacuum drying behavior of Zizyphus jujuba Miller slices was experimentally investigated at the temperature of 50, 60, and 70 °C and the mathematical models were used to fit the thin-layer vacuum drying of Z. jujuba slices. The increase in drying air temperature resulted in a decrease in drying time. The drying rate was found to increase with temperature, thereby reducing the total drying time. It was found that Z. jujuba slices with thickness of 4 mm would be dried up to 0.08 kg water/kg dry matter in the range of 180-600 min in the vacuum dryer at the studied temperature range from 70 to 50 °C. The Midilli et al. model was selected as the most appropriate model to describe the thin-layer drying of Z. jujuba slices. The diffusivity coefficient increased linearly over the temperature range from 1.47 × 10(-10) to 3.27 × 10(-10) m(2)/s, as obtained using Fick's second law. The temperature dependence of the effective diffusivity coefficient followed an Arrhenius-type relationship. The activation energy for the moisture diffusion was determined to be 36.76 kJ/mol. PMID:24425895

  6. The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds.

    Science.gov (United States)

    Hashemi, Seyyed Abbas; Madani, Seyyed Abdollah; Abediankenari, Saied

    2015-01-01

    Treatment of wounds is very important and was subject of different investigations. In this regard, natural substance plays crucial role as complementary medicine. Various studies reported that aloe vera has useful effects on wounds especially cutaneous wounds healing. Therefore in the current review, we examined the effect of aloe vera on cutaneous wound healing and concluded that although aloe vera improves the wound healing as well as other procedures both clinically and experimentally, more studies are still needed to approve the outcomes.

  7. Quality Characteristics, Nutraceutical Profile, and Storage Stability of Aloe Gel-Papaya Functional Beverage Blend

    OpenAIRE

    Pushkala Ramachandran; Srividya Nagarajan

    2014-01-01

    Aloe vera gel, well known for its nutraceutical potential, is being explored as a functional ingredient in a wide array of health foods and drinks. Processing of exotic fruits and herbal botanicals into functional beverage is an emerging sector in food industry. The present study was undertaken to develop a spiced functional RTS beverage blend using Aloe gel (AG) and papaya. Aloe gel (30%), papaya pulp (15%), spice extract (5%), and citric acid (0.1%) were mixed in given proportion to prepare...

  8. The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds

    OpenAIRE

    Seyyed Abbas Hashemi; Seyyed Abdollah Madani; Saied Abediankenari

    2015-01-01

    Treatment of wounds is very important and was subject of different investigations. In this regard, natural substance plays crucial role as complementary medicine. Various studies reported that aloe vera has useful effects on wounds especially cutaneous wounds healing. Therefore in the current review, we examined the effect of aloe vera on cutaneous wound healing and concluded that although aloe vera improves the wound healing as well as other procedures both clinically and experimentally, mor...

  9. On possibilities of application of Miller formula for determination of parameters of Micropixel Avalanche Photodiodes

    CERN Document Server

    Sadygov, Z; Akhmedov, G; Akhmedov, F; Mukhtarov, R; Sadygov, A; Titov, A; Zhezher, V

    2014-01-01

    Miller formula modified to take into account voltage drop on serial resistor of an avalanche photodiode is considered. It is proven by experimental data that modified Miller formula can describe operation of both regular and micropixel avalanche photodiodes with good enough precision. It is shown that operation parameters of the devices can be determined using a linear extrapolation of the voltage-current curve for both regular avalanche photodiode and the one operating in Geiger mode.

  10. The application of the Modigliani-Miller theorem to Japanese industry

    OpenAIRE

    Katirai, Farzad.

    1984-01-01

    The purpose of this thesis is to study some aspects of Japanese corporate finance, using the analytical tools of the Modigliani-Miller theorem. The Modigliani Miller theorem is a fundamental element in the theory of finance, and establishes the conditions under which the financial structure of the firm is irrelevant to the determination of real corporate values. In its simplest form the theorem requires the presence of perfect capital markets. In the real world,- howe...

  11. Processing, food applications and safety of aloe vera products: a review.

    Science.gov (United States)

    Ahlawat, Kulveer Singh; Khatkar, Bhupender Singh

    2011-10-01

    Aloe vera is used for vigor, wellness and medicinal purposes since rigvedic times. Health benefits of aloe vera include its application in wound healing, treating burns, minimizing frost bite damage, protection against skin damage from x-rays, lung cancer, intestinal problems, increasing high density lipoprotein (HDL), reducing low density lipoprotein (LDL), reducing blood sugar in diabetics, fighting acquired immune deficiency syndrome (AIDS), allergies and improving immune system. Phytochemistry of aloe vera gel has revealed the presence of more than 200 bioactive chemicals. Aloe vera gel is extracted from its leaves and appropriate processing techniques are needed for stabilization as well as preparation of the end products. The industries involved in processing of aloe vera need Government surveillance to ensure that the aloe vera products have beneficial bio-active chemicals as per claims of the manufacturers. Regulatory bodies also need to look into the safety and toxicological aspects of aloe vera products for food applications. The claims made for medicinal value of aloe products should be supported by authentic and approved clinical trial data. It is presumptive to mention that nutraceutical claims of aloe products made by the manufacturers are numerous. However, approved clinical evidences are available only for lowering LDL, increasing HDL, decreasing blood glucose level, treating genital herpes and psoriases.

  12. Processing, food applications and safety of aloe vera products: a review.

    Science.gov (United States)

    Ahlawat, Kulveer Singh; Khatkar, Bhupender Singh

    2011-10-01

    Aloe vera is used for vigor, wellness and medicinal purposes since rigvedic times. Health benefits of aloe vera include its application in wound healing, treating burns, minimizing frost bite damage, protection against skin damage from x-rays, lung cancer, intestinal problems, increasing high density lipoprotein (HDL), reducing low density lipoprotein (LDL), reducing blood sugar in diabetics, fighting acquired immune deficiency syndrome (AIDS), allergies and improving immune system. Phytochemistry of aloe vera gel has revealed the presence of more than 200 bioactive chemicals. Aloe vera gel is extracted from its leaves and appropriate processing techniques are needed for stabilization as well as preparation of the end products. The industries involved in processing of aloe vera need Government surveillance to ensure that the aloe vera products have beneficial bio-active chemicals as per claims of the manufacturers. Regulatory bodies also need to look into the safety and toxicological aspects of aloe vera products for food applications. The claims made for medicinal value of aloe products should be supported by authentic and approved clinical trial data. It is presumptive to mention that nutraceutical claims of aloe products made by the manufacturers are numerous. However, approved clinical evidences are available only for lowering LDL, increasing HDL, decreasing blood glucose level, treating genital herpes and psoriases. PMID:23572784

  13. Processing and characterization of Aloe vera gel for hydrogel preparation

    International Nuclear Information System (INIS)

    This work describes the processing and characterization of Aloe vera gel for the preparation of hydrogels through gamma radiation from polymers and natural products in order to be used in biomedical applications. Processing was carried out immersing slices of aloe in distilled water for phenolic compound extraction. Through UV-VIS spectroscopy, 48 hours was determined as the optimal soaking time, at which organoleptic characteristics of the gel as well as its pH were acceptable. An increase of pH was observed on the gel that was stored at room temperature. The non processed gel showed a pink coloration. Results of gel yield values were not high. Microbiological tests showed a high bioburden. (author)

  14. Development of Aloe vera based edible coating for tomato

    Science.gov (United States)

    Athmaselvi, K. A.; Sumitha, P.; Revathy, B.

    2013-12-01

    The effect of formulated Aloe vera based edible coating on mass loss, colour, firmness, pH, acidity, total soluble solid, ascorbic acid and lycopene on the coated tomato was investigated. The tomato in control showed a rapid deterioration with an estimated shelf life period of 19 days, based on the mass loss, colour changes, accelerated softening and ripening. On the contrary, the coating on tomatoes delayed the ripening and extended the shelf life up to 39 days. The physiological loss in weight was 7.6 and 15.1%, firmness was 36 and 46.2 N on 20th day for control and coated tomatoes, respectively. From the results, it was concluded that the use of Aloe vera based edible coating leads to increased tomato shelf-life.

  15. Memristors in the electrical network of Aloe vera L.

    Science.gov (United States)

    Volkov, Alexander G; Reedus, Jada; Mitchell, Colee M; Tucket, Clayton; Forde-Tuckett, Victoria; Volkova, Maya I; Markin, Vladislav S; Chua, Leon

    2014-01-01

    A memristor is a resistor with memory, which is a non-linear passive two-terminal electrical element relating magnetic flux linkage and electrical charge. Here we found that memristors exist in vivo. The electrostimulation of the Aloe vera by bipolar sinusoidal or triangle periodic waves induce electrical responses with fingerprints of memristors. Uncouplers carbonylcyanide-3-chlorophenylhydrazone and carbonylcyanide-4-trifluoromethoxy-phenyl hydrazone decrease the amplitude of electrical responses at low and high frequencies of bipolar periodic sinusoidal or triangle electrostimulating waves. Memristive behavior of an electrical network in the Aloe vera is linked to the properties of voltage gated ion channels: the K(+) channel blocker TEACl reduces the electric response to a conventional resistor. Our results demonstrate that a voltage gated K(+) channel in the excitable tissue of plants has properties of a memristor. The discovery of memristors in plants creates a new direction in the modeling and understanding of electrical phenomena in plants.

  16. Aloe vera Induced Biomimetic Assemblage of Nucleobase into Nanosized Particles

    OpenAIRE

    Chauhan, Arun; Zubair, Swaleha; Sherwani, Asif; Owais, Mohammad

    2012-01-01

    Aim Biomimetic nano-assembly formation offers a convenient and bio friendly approach to fabricate complex structures from simple components with sub-nanometer precision. Recently, biomimetic (employing microorganism/plants) synthesis of metal and inorganic materials nano-particles has emerged as a simple and viable strategy. In the present study, we have extended biological synthesis of nano-particles to organic molecules, namely the anticancer agent 5-fluorouracil (5-FU), using Aloe vera lea...

  17. STUDIES ON THE EFFICACY OF ALOE VERA ON ANTIMICROBIAL ACTIVITY

    OpenAIRE

    T.Karpagam; R. Aruna Devaraj

    2011-01-01

    The aqueous, ethanolic, methanolic, petroleum ether and acetone extracts of Aloe vera were screened for anti-microbial activity using the Minimal Inhibitory Concentration (MIC) method. They were tested against five bacteria (Escherischia coli, Pseudomonas aeruginosa, Bacillus subtilis, Klebsiella pneumonia and Staphylococcus aureus). The susceptibility of the microorganisms to the extracts in different concentrations plants were compared. The active component in the extract was determined us...

  18. Antibacterial activities and antioxidant capacity of Aloe vera

    OpenAIRE

    Nejatzadeh-Barandozi, Fatemeh

    2013-01-01

    Background The aim of this study was to identify, quantify, and compare the phytochemical contents, antioxidant capacities, and antibacterial activities of Aloe vera lyophilized leaf gel (LGE) and 95% ethanol leaf gel extracts (ELGE) using GC-MS and spectrophotometric methods. Results Analytically, 95% ethanol is less effective than ethyl acetate/diethyl ether or hexane (in the case of fatty acids) extractions in separating phytochemicals for characterization purposes. However, although fewer...

  19. ANTIMICROBIAL AND PHYTOCHEMICAL ANALYSIS OF ALOE VERA L

    OpenAIRE

    Mariappan V; Shanthi G

    2012-01-01

    The present study was made to attempt the antimicrobial and phytochemical analysis of Aloe vera L (babosa). The antimicrobial activity method was using Muller and Hinton agar Dimethyl sulfoxide (DMSO) was used. The Overnight incubated bacterial culture, Staphylococcus aureus, Bacillus subtillis, Proteus vulgaris, Pseudomonas aeroginosa, Enterobacter aerogenes, Klebshiella sp, Salmonella sp, Shigella sonie, S. spidermiods. In phytochemical studies, the leaf extract were analysed for the flavon...

  20. Encapsulation of Aloe Vera and Its Effect During Yogur Incubation

    Directory of Open Access Journals (Sweden)

    Ricardo Adolfo Parra Huertas

    2014-11-01

    Full Text Available The yogurt is milk derivative highly consumed around the world,as well as aloe vera. Both have reports tocontribute to human health. The purpose of this research is to determine the effect of the addition of capsules with aloe vera during the incubation of yogurt. Aloeverawas encapsulated in alginate at two different concentrations, 1% and 2%,addingthe capsules from the moment of incubation and comparing the effect of the addition of capsules withthe non-addition of them. For these samples were determined: pH, acidity, syneresis, lactic acid bacteria count, sensory evaluation and proximate analysis. The results indicated that for the three treatments pH values and acid behaved similarly to each characteristic of the yogurt during incubation. The lactic acid bacteria count indicated that treatment with capsules containing 2% sodium alginate had higher counts. Sensorially, three treatments had a favorable acceptability; proximate analysis had favorable values . In conclusion,the tests showed the viability of encapsulated aloe vera in the manufacture of yogurt during incubation time without being affected by the concentration of sodium alginate.

  1. Arquitetura, anatomia e histoquímica das folhas de Gomphrena arborescens L.f. (Amaranthaceae Architecture, anatomy and histochemistry of the leaves of Gomphrena arborescens L.f. (Amaranthaceae

    Directory of Open Access Journals (Sweden)

    Suzane Margaret Fank-de-Carvalho

    2005-06-01

    Full Text Available As folhas de Gomphrena arborescens L.f., nativa do Cerrado, são utilizadas contra dismenorréia na medicina popular. As investigações morfológica, anatômica e histoquímica das folhas visam fornecer elementos para taxonomia, para controle de qualidade de drogas e identificação microscópica de fitoterápicos. Folhas foram coletadas em Brasília, DF, nas áreas de Cerrado do Centro Olímpico da Univesidade de Brasília e na Reserva Ecológica do IBGE. Foram efetuadas análises morfológicas, anatômicas e histoquímicas. Os estudos de arquitetura foliar, densidade estomática e de vênulas terminais foram efetuados em folhas diafanizadas, apresentando médias de 42,39±15,50 estômatos mm-2 e 11,7±3,55 vênulas terminais mm². As folhas apresentaram duas formas de tricomas tectores. O mesofilo bilateral apresenta tecido clorenquimático disposto radialmente à bainha parenquimática completa que envolve os feixes vasculares, características da síndrome Kranz associada ao ciclo fotossintético C4. O amido concentra-se na bainha parenquimática. As folhas são ricas em celulose, drusas de oxalato de cálcio, proteínas, lignina e outros compostos fenólicos, entre eles os flavonóides. As folhas apresentam morfologia variável, mas o padrão anatômico e de venação são constantes.Leaves of the Brazilian Cerrado plant Gomphrena arborescens L.f. are used against dismenorea in popular medicine. The morphological, anatomical and histochemical investigation aims to help taxonomy, quality control of drugs and microscopical identification of phytotherapics. The leaves have been collected in Brasília, DF, in the Olympical Center of the University of Brasilia and in the Ecological Reserve of IBGE. The leaf architecture, stomatal and veinlet densities have been studied in clarified leaves, presenting average of 42,39±15,50 stomata mm² and 11,7±3,55 veinlet mm-2. Leaves presented two forms of tector trichomes. The bilateral mesophyll

  2. Human radiation studies: Remembering the early years. Oral history of radiologist Earl R. Miller, M.D., August 9 and 17, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    Dr. Earl R. Miller was interviewed by representatives of US DOE Office of Human Radiation Research (OHRE). The interview covers Dr. Miller`s involvement with the Manhattan Engineer District, with total body irradiation, and heavy-ion therapy. Dr. Miller`s remembrances include wartime work on radiation exposure, Joe Hamilton, Neutron Therapy research, means of obtaining isotopes, consent forms, infinite laminograms, invention of a baby holder to alleviate exposure of radiological technicians in diagnostic procedures involving infants, and several personages.

  3. Cerebellar and pontine tegmental hypermetabolism in miller-fisher syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yu Kyrong; Kim, Ji Soo; Lee, Won Woo; Kim, Sang Eun [Seoul National Univ. College of Medicine, Seoul (Korea, Republic of)

    2007-07-01

    Miller Fisher syndrome (MFS) has been considered as a variant of Guillain-Barre syndrome (GBS), a type of acute immune neuropathies involving peripheral nerve system. Unlike GBS, presence of cerebellar type ataxia and supranuclear ophthalmioplesia in MFS suggests additional involvement of the central nervous system. To determine involvement of the central nervous system in MFS, we investigated the cerebral metabolic abnormalities in patients with MFS using FDG PET. Nine patients who were diagnosed as MFS based on acute ophthalmoplegia, ataxia, and areflexia without other identifiable causes participated in this study. In six patients, serum antibodies possibly related with symptom of MFS (anti- GQ1b or anti-GM1) were detected at the time of the study. With the interval of 25 26 days (range: 3-83 days) from the symptom on set, brain FDG PET were underwent in patients and compared with those from healthy controls. In group analysis comparing with healthy controls, FDG PET of patients revealed increased metabolism in the bilateral cerebellar hemispheres and vermis, and the thalamus. In contrast, the occipital cortex showed decreased metabolism. Individual analyses disclosed hypermetabolism in the cerebellar vermis or hemispheres in 5, and in the pontine tegmentum in 2 of the 9 patients. We also found that the cerebellar vermian hypermetabolism was inversely correlated with the interval between from the symptom on set to PET study. Moreover, follow-up PET of a patient demonstrated that cerebellar hypermetabolism decreased markedly with an improvement of the ophthalmoplegia and ataxia. These findings indicate an involvement of the central nervous system in MFS and suggest an antibody-associated acute inflammatory process as a mechanism of this disorder.

  4. DIVERSITY ANALYSIS OF DIFFERENT ACCESSIONS OF ALOE BARBADENSIS MILL. (SYN. ALOE VERA .L) COLLECTED FROM RAJASTHAN USING RAPD MARKER SYSTEM

    OpenAIRE

    DINESH CHANDRA; PREETI CHOUDHARY

    2014-01-01

    Under a survey and collection programme of National Agricultural Technology Project (NATP), various accessions of Aloe vera were collected from Rajasthan and Gujarat. In this study 10 Accessions from Rajasthan were characterized through RAPD. RAPD revealed 32.08 per cent polymorphic bands detecting 11.9% average diversity among the accessions studied. The diversity ranged from 4.3% to 20.4%. The primers like OPG-15 having high PIC value (0.346) are considered important for diversi...

  5. Composite wound dressings of pectin and gelatin with aloe vera and curcumin as bioactive agents.

    Science.gov (United States)

    Tummalapalli, Mythili; Berthet, Morgane; Verrier, Bernard; Deopura, B L; Alam, M S; Gupta, Bhuvanesh

    2016-01-01

    Aloe vera and curcumin loaded oxidized pectin-gelatin (OP-Gel) matrices were used as antimicrobial finishes on nonwoven cotton fabrics to produce composite wound care devices. The drug release characteristics of the biocomposite dressings indicated that curcumin is released through a biphasic mechanism - erosion of the polymeric matrix, followed by diffusion, while aloe vera is released upon leaching of the polymeric matrix. A 50/50 composition of aloe vera/curcumin was used to fabricate OP-Gel-Aloe Curcumin dressings. However, contrary to our expectations, OP-Gel-Aloe Curcumin dressings exhibited lesser antimicrobial activity compared to OP-Gel-Aloe and OP-Gel-Curcumin dressings. The cytocompatibility of the fabricated dressings was evaluated using NIH3T3 mouse fibroblast cells. OP-Gel-Aloe treated fibroblasts had the highest viability, with the matrices providing a substrate for good cell attachment and proliferation. On the other hand, OP-Gel-Curcumin and OP-Gel-Aloe Curcumin seemed to have induced apoptosis in NIH3T3 cells. In vivo wound healing analysis was carried out using an excisional splint wound model on C57BL/6J mice. OP-Gel-Aloe treated wounds exhibited very rapid healing with 80% of the wound healing in just 8 days. Furthermore, aloe vera exerted a strong anti-inflammatory effect and prominent scar prevention. Histological examination revealed that an ordered collagen formation and neovascularization could be observed along with migration of nuclei. Therefore, OP-Gel-Aloe biocomposite dressings are proposed as viable materials for effective wound management.

  6. Composite wound dressings of pectin and gelatin with aloe vera and curcumin as bioactive agents.

    Science.gov (United States)

    Tummalapalli, Mythili; Berthet, Morgane; Verrier, Bernard; Deopura, B L; Alam, M S; Gupta, Bhuvanesh

    2016-01-01

    Aloe vera and curcumin loaded oxidized pectin-gelatin (OP-Gel) matrices were used as antimicrobial finishes on nonwoven cotton fabrics to produce composite wound care devices. The drug release characteristics of the biocomposite dressings indicated that curcumin is released through a biphasic mechanism - erosion of the polymeric matrix, followed by diffusion, while aloe vera is released upon leaching of the polymeric matrix. A 50/50 composition of aloe vera/curcumin was used to fabricate OP-Gel-Aloe Curcumin dressings. However, contrary to our expectations, OP-Gel-Aloe Curcumin dressings exhibited lesser antimicrobial activity compared to OP-Gel-Aloe and OP-Gel-Curcumin dressings. The cytocompatibility of the fabricated dressings was evaluated using NIH3T3 mouse fibroblast cells. OP-Gel-Aloe treated fibroblasts had the highest viability, with the matrices providing a substrate for good cell attachment and proliferation. On the other hand, OP-Gel-Curcumin and OP-Gel-Aloe Curcumin seemed to have induced apoptosis in NIH3T3 cells. In vivo wound healing analysis was carried out using an excisional splint wound model on C57BL/6J mice. OP-Gel-Aloe treated wounds exhibited very rapid healing with 80% of the wound healing in just 8 days. Furthermore, aloe vera exerted a strong anti-inflammatory effect and prominent scar prevention. Histological examination revealed that an ordered collagen formation and neovascularization could be observed along with migration of nuclei. Therefore, OP-Gel-Aloe biocomposite dressings are proposed as viable materials for effective wound management. PMID:26529192

  7. Physicochemical characterization of silver nanoparticles synthesize using Aloe Vera (Aloe barbadensis)

    Science.gov (United States)

    Kuponiyi, Abiola; Kassama, Lamin; Kukhtareva, Tatiana

    2014-08-01

    Production of silver nanoparticles (AgNPs) using different biological methods is gaining recognition due to their multiple applications. Although, several physical and chemical methods have been used for the synthesis and stabilizing of AgNPs, yet, a green chemistry method is preferable because it is cost effective and environmentally friendly. The synthesis was done using Aloe Vera (AV) extract because it has chemical compounds such as "Antrokinon" that are known for its antibacterial, antivirus and anticancer properties. We hypothesize that AV extract can produce a stable nanoparticles within the 100 nm range and be biologically active. The biological compounds were extracted from AV skin with water and ethanol which was used as the reduction agent for the synthesis of nanoparticles. The biological extract and AgNO3 were blended and heated to synthesize AgNPs. The reaction process was monitored using UV-Visible spectroscopy. Fourier Transfer Infrared spectroscopy (FTIR) was used for the characterization of biological compounds and their substituent groups before and after the reaction process. Dynamic Light scattering (DLS) method was used to characterize particle size of AgNPs and their biomolecular stability. Results showed that biological compounds such as aliphatic amines, alkenes (=C-H), alkanes (C-H), alcohol (O-H) and unsaturated esters(C-O), which has an average particle size of 109 and 215.8 nm and polydispersity index of 0.451 and 0.375 for ethanol and water extract, respectively. According to TEM measurements the size of AgNPs are in the range 5-20 nm The results suggested that ethanol derived AgNPs contained higher yield of organic compounds, thus has better solubility power than water. Ag NPs can be used to control salmonella in poultry industry.

  8. Pelargonium graveolens L'Her. and Artemisia arborescens L. essential oils: chemical composition, antifungal activity against Rhizoctonia solani and insecticidal activity against Rhysopertha dominica.

    Science.gov (United States)

    Bouzenna, Hafsia; Krichen, Lamia

    2013-01-01

    The chemical composition of the Pelargonium graveolens essential oil allowed the identification of 15 compounds (93.86% of the total essential oil). The major fractions were citronellol (35%) and geraniol (28.8%). The chemical composition of the Artemisia arborescens essential oil revealed twenty-one compounds representing 93.57% of the total essential oil. The main compounds were chamazulene (31.9%) and camphor (25.8%). The insecticidal effects were tested towards the insect Rhysopertha dominica. Results revealed that these two essential oils were highly effective against R. dominica at the dose of 50 µL on Petri dish of 8.5 cm of diameter. The antifungal activity was evaluated against Rhizoctonia solani and results showed that both of the essential oils were highly active at a dose of 12.5 µL/20 mL of PDA. Moreover, the inhibitory effect of P. graveolens essential oil was evidenced as stronger than that of the A. arborescens oil for all the tested doses.

  9. DNA degradation by aqueous extract of Aloe vera in the presence of copper ions.

    Science.gov (United States)

    Naqvi, Shoa; Ullah, M F; Hadi, S M

    2010-06-01

    The plant Aloe vera has long been used in medicine, as dietary supplements and for cosmetic purposes. Aloe vera extracts are a rich source of polyphenols, such as aloin and aloe emodin and have shown a wide range of pharmacological properties, including anti-inflammatory and anti-cancer properties. The bioactive component aloe emodin has been reported to induce apoptosis in various cancer cell lines. Many of the biological activities of Aloe vera have been attributed to its antioxidant properties. However, most plant-derived polyphenols that are also present in Aloe vera may exhibit pro-oxidant properties either alone or in the presence of transition metals, such as copper. Previous reports from this laboratory have implicated the pro-oxidant action as one of the mechanisms for their anti-cancer properties. In the present paper, we show that aqueous extract of Aloe vera is also able to cause DNA degradation in the presence of copper ions. Further, the extract is also able to reduce Cu(II) to Cu(I) and generate reactive oxygen species, such as superoxide anion and hydroxyl radicals in a dose-dependent manner, which correlates with ability of the extract to cause DNA breakage. Thus, the study shows that in addition to antioxidant activity, Aloe vera extract also possess pro-oxidant properties, leading to oxidative DNA breakage.

  10. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ERα Inhibition

    Directory of Open Access Journals (Sweden)

    Pao-Hsuan Huang

    2013-01-01

    Full Text Available The anthraquinones emodin and aloe-emodin are abundant in rhubarb. Several lines of evidence indicate that emodin and aloe-emodin have estrogenic activity as phytoestrogens. However, their effects on estrogen receptor α (ERα activation and breast cancer cell growth remain controversial. The goal of this study is to investigate the effects and molecular mechanisms of emodin and aloe-emodin on breast cancer cell proliferation. Our results indicate that both emodin and aloe-emodin are capable of inhibiting breast cancer cell proliferation by downregulating ERα protein levels, thereby suppressing ERα transcriptional activation. Furthermore, aloe-emodin treatment led to the dissociation of heat shock protein 90 (HSP90 and ERα and increased ERα ubiquitination. Although emodin had similar effects to aloe-emodin, it was not capable of promoting HSP90/ERα dissociation and ERα ubiquitination. Protein fractionation results suggest that aloe-emodin tended to induce cytosolic ERα degradation. Although emodin might induce cytosolic ERα degradation, it primarily affected nuclear ERα distribution similar to the action of estrogen when protein degradation was blocked. In conclusion, our data demonstrate that emodin and aloe-emodin specifically suppress breast cancer cell proliferation by targeting ERα protein stability through distinct mechanisms. These findings suggest a possible application of anthraquinones in preventing or treating breast cancer in the future.

  11. Bacterial leaf rot of Aloe vera L., caused byErwinia chrysanthemi biovar 3

    NARCIS (Netherlands)

    Laat, de P.C.A.; Verhoeven, J.T.W.; Danse, J.D.

    1994-01-01

    A severe attack of the bacteriumErwinia chrysantemi biovar 3 on the succulentAloe vera on the Carribean island of Aruba is described. Biochemical and pathological characteristics of strains are presented, including results of successful inoculation experiments onAloe vera. This is the first report o

  12. Pengeringan Lidah Buaya (AloVera Menggunakan Oven Gelombang Mikro (Microwave Oven

    Directory of Open Access Journals (Sweden)

    Edy Hartulistiyoso

    2011-10-01

    Full Text Available Aloe vera (Aloe vera is known as a useful plant, both as food, cosmetics or pharmaceuticals. Due its high water content, Aloe vera should be processed immediately after harvest. This paper will discuss the drying of aloe vera using microwave oven. The drying process of 50 gr Aloe vera gel and rind using 80 Watts microwave power completed in 140 minutes to reach the final moisture content of 7% wet basis. The drying process in microwave drying shows similar process to that of conventional drying. Dipolar rotation mechanism of water molecules at microwave drying does not affect the drying stage. It shows however shorter process time. The water removal of the drying material occurred in the early minutes until the 50th minute. This because of the high free water surface on the material, while from minute 50 to minute 140 slowed the drying process. Highest temperature of the material during the process is achieved at 57.6 oC in drying of gel and 70.7 oC in drying of Aloe vera rind. It is expected that there is no damage of nutritional content during drying in the this temperature range. Quality analysis of flour and tea of Aloe vera after drying by microwave showed that Aloe vera powder produced within the range of the standard, both visually and microbiologically, but indicated as low quality when viewed from acid content levels. Whether microwave heating mechanism affects the acidity, this needs further study.

  13. 映山红开花习性与花粉生活力研究%Study on the Flowering Habit and Pollen Viability of R. arborescens Planch

    Institute of Scientific and Technical Information of China (English)

    卜志国; 杜绍华; 张晓曼

    2011-01-01

    [目的]探讨映山红的开花习性及花粉生活力.[方法]以映山红(Rhododendron arborescens)为试验材料.观察映山红(R.simisiiPlanch)开花的习性;采用离体培养基萌发测定法,以及培养基中蔗糖的浓度、培养温度、硼酸、钙离子等因素对花粉萌发和花粉管伸长的影响.[结果]映山红花期4~6月,单花期3~5 d;花紫色,2~6朵簇生于枝端;花萼5裂,长2~4 mm;花冠宽漏斗状,长4~5 cm,5裂;雄蕊7~10,花药紫色;柱头头状.蔗糖浓度为5%时映山红花粉萌发最好;光照条件下25℃时萌发率最高,达70%以上;培养基为20mg/L硼酸+10mg/L氯化钙+5%蔗糖+0.5 g琼脂,萌发率最高达87%;在一定浓度(0~20 mg/L)范围内,钙离子对映山红花粉的萌发率影响不大,主要影响花粉管长度;对花粉萌发率的影响比较明显,浓度间差异均达显著水平,在一定硼酸浓度(0~20 mg/L)范围内,随着硼酸浓度的增加花粉的萌发率上升.[结论]该研究可为今后利用映山红开展人工育种奠定基础.%[ Objective ] To investigate the flowering habit and pollen viability of R. arborescens Planch. [ Method ] R. arborescens Planch as test material, effects of sucrose concentrations, culture temperature, boric acid and Ca2+ on the pollen germination and tube growth were studied through in vitro culture method. [ Result ] The flower season of R. arborescens Planch lasts 4 to 6 months with single flowering phase of 3 - 5 d;purple, 2 -6 flowers cluster in the end of branches; calyx 5-lobed, 2-4 mm in length; funnel-form corolla, 4 -5 cm in length, 5-lobed; 7 -10 stamens, purple anther; capitate stigmas. 5% sucrose was proved to be the best for the germination of pollen, and the germination rate was the highest at 25 ℃ in daylight ( more than 70% ); the optimum combination for the germination of pollen was 20 mg/L boric acid + 10 mg/L CaCl2 +5% sucrose +0.5% agar, under this condition, the germination rate reached as high as

  14. Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria.

    Science.gov (United States)

    Fani, Mohammadmehdi; Kohanteb, Jamshid

    2012-03-01

    Aloe vera is a medicinal plant with anti-inflammatory, antimicrobial, antidiabetic and immune-boosting properties. In the present study we investigated the inhibitory activities of Aloe vera gel on some cariogenic (Streptococcus mutans), periodontopathic (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis) and an opportunistic periodontopathogen (Bacteroides fragilis) isolated from patients with dental caries and periodontal diseases. Twenty isolates of each of these bacteria were investigated for their sensitivity to Aloe vera gel using the disk diffusion and microdilution methods. S. mutans was the species most sensitive to Aloe vera gel with a MIC of 12.5 µg/ml, while A. actinomycetemcomitans, P. gingivalis, and B. fragilis were less sensitive, with a MIC of 25-50 µg/ml (P Aloe vera gel at optimum concentration could be used as an antiseptic for prevention of dental caries and periodontal diseases.

  15. Assessment of Anti HSV-1 Activity of Aloe Vera Gel Extract: an In Vitro Study

    Science.gov (United States)

    Rezazadeh, Fahimeh; Moshaverinia, Maryam; Motamedifar, Mohammad; Alyaseri, Montazer

    2016-01-01

    Statement of the Problem Herpes simplex virus (HSV) infection is one of the most common and debilitating oral diseases; yet, there is no standard topical treatment to control it. The extract of Aloe vera leaves has been previously reported to have anti-inflammatory, antibacterial, and also antiviral effects. There is no data on anti-Herpes simplex virus type 1 (HSV-1) activity of Aloe vera gel. Purpose This study aimed to evaluate the anti-HSV-1 activity of Aloe vera gel in Vero cell line. Materials and Method In this study, gel extraction and cytotoxicity of various increasing concentrations of Aloe vera gel (0.2, 0.5, 1, 2, and 5%) was evaluated in Dulbecco’s Modified Eagle Medium (DMEM) containing 2% fetal bovine serum (FBS). Having been washed with phosphate buffered saline, 50 plaque-forming units (PFU) of HSV-1 was added to each well. After 1 hour of incubation at 37°C, cell monolayers in 24 well plates were exposed to different increasing concentrations of Aloe vera gel. The anti-HSV-1 activity of Aloe vera gel in different concentrations was assessed by plaque reduction assays. Data were analyzed by using One-way ANOVA. Results The cytotoxicity assay showed that Aloe vera in prearranged concentrations was cell-compatible. The inhibitory effect of various concentrations of Aloe vera was observed one hour after the Vero cell was infected with HSV-1. However, there was no significant difference between two serial concentrations (p> 0.05). One-way ANOVA also revealed no significant difference between the groups. The findings indicated a dose-dependent antiviral effect of Aloe vera. Conclusion The findings showed significant inhibitory effect of 0.2-5% Aloe vera gel on HSV-1 growth in Vero cell line. Therefore, this gel could be a useful topical treatment for oral HSV-1 infections without any significant toxicity. PMID:26966709

  16. Biocontrol potential of Trichoderma harzianum isolate T-aloe against Sclerotinia sclerotiorum in soybean.

    Science.gov (United States)

    Zhang, Fuli; Ge, Honglian; Zhang, Fan; Guo, Ning; Wang, Yucheng; Chen, Long; Ji, Xiue; Li, Chengwei

    2016-03-01

    Sclerotinia stem rot, caused by Sclerotinia sclerotiorum (Lib.) de Bary is a major disease of soybean (Glycine max (L.) Merr.). At present, we revealed the three-way interaction between Trichoderma harzianum T-aloe, pathogen S. sclerotiorum and soybean plants in order to demonstrate biocontrol mechanism and evaluate biocontrol potential of T-aloe against S. sclerotiorum in soybean. In our experiments, T-aloe inhibited the growth of S. sclerotiorum with an efficiency of 56.3% in dual culture tests. T-aloe hyphae grew in parallel or intertwined with S. sclerotiorum hyphae and produced hooked contact branches, indicating mycoparasitism. Plate tests showed that T-aloe culture filtrate inhibited S. sclerotiorum growth with an inhibition efficiency of 51.2% and sclerotia production. T-aloe pretreatment showed growth-promoting effect on soybean plants. The activities of peroxidase, superoxide dismutase, and catalase increased, and the hydrogen peroxide (H2O2) as well as the superoxide radical (O2(-)) content in soybean leaves decreased after T-aloe pretreatment in response to S. sclerotiorum pathogen challenge. T-aloe treatment diminished damage caused by pathogen stress on soybean leaf cell membrane, and increased chlorophyll as well as total phenol contents. The defense-related genes PR1, PR2, and PR3 were expressed in the leaves of T-aloe-treated plants. In summary, T-aloe displayed biocontrol potential against S. sclerotiorum. This is the first report of unraveling biocontrol potential of Trichoderma Spp. to soybean sclerotinia stem rot from the three-way interaction between the biocontrol agent, pathogen S. sclerotiorum and soybean plants. PMID:26774866

  17. The effect of Aloe vera leaf gel on fatty streak formation in hypercholesterolemic rabbits

    Directory of Open Access Journals (Sweden)

    Nasim Dana

    2012-01-01

    Full Text Available Background: Atherosclerosis is a complex disease that is associated with a variety of etiologic factors such as hyperlipidemia and inflammation. Aloe vera (Liliaceae family has been used traditionally as an anti-inflammatory drug. The aims of this survey were to define the beneficial effects of Aloe vera leaf gel on some of the atherosclerosis risk factors, and also fatty streak formation in hypercholesterolemic rabbits. Materials ans Methods : 32 white male rabbits were randomly divided into four experimental groups (n = 8, each. During the study, the animals had a standard diet (control group, high cholesterol diet (HC group, high cholesterol diet with Aloe vera leaf gel (3.2%v/v (HC+ Aloe group and Aloe vera leaf gel (Aloe group for 30 days. Fasting blood samples were collected from all animals at the beginning and end of the study. Then total cholesterol (TC, fasting blood sugar (FBS, triglyceride (TG and CRP were measured before and after experimental periods. By the end of the study, the aortas were removed and investigated for atherosclerosis plaque formation. Results: Significant differences were observed in TC and CRP levels of the high-cholesterol diet with Aloe vera and the high-cholesterol diet alone (p < 0.05. The formation of fatty streaks in the aorta was also significantly lower in the same animals under the influence of dietary Aloe vera(p < 0.05. The control and Aloe group did not show any evidence of atherosclerosis. No significant difference was found between the groups in TG and FBS. Conclusions: The data suggests that Aloe vera has beneficial effects on the prevention of fatty streak development; it may reduce the development of atherosclerosis through modification of risk factors. However, further studies are needed to understand the mechanisms whereby this plant exerts its anti-atherosclerotic effects.

  18. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review.

    Science.gov (United States)

    Lee, Jeonghun; Lee, Mi Sun; Nam, Kwan Woo

    2014-07-01

    Aloe is one of the leading products used in phytomedicine. Several cases of aloe-induced toxic hepatitis have been reported in recent years. However, its toxicology has not yet been systematically described in the literature. A 21-year-old female patient was admitted to our hospital with acute hepatitis after taking an aloe vera preparation for four weeks. Her history, clinical manifestation, laboratory findings, and histological findings all led to the diagnosis of aloe vera-induced toxic hepatitis. We report herein on a case of acute toxic hepatitis induced by aloe vera.

  19. Water Level Measurement in Floodplain using ALOS PALSAR

    OpenAIRE

    Won, Joong-Sun

    2011-01-01

    L-band interferometric SAR (InSAR) has been used to detect a relative water level change in the floodplain of the Tonle Sap, Cambodia. The goal of this research is a pattern and trend analysis of flooding around the Tonle Sap. The flood pattern over the Tonle Sap area during 2007-2011 has been examined using ALOS PALSAR to monitor the flood pattern, water level fluctuation and the area of flood around the Tonle Sap. Previous studies had shown L-band SAR interferometry is a useful method for t...

  20. Study on the Extraction Technology of Flavonoids from Aloe arborescens Mill.by Microwave Method%微波法提取木立芦荟黄酮类化合物的工艺研究

    Institute of Scientific and Technical Information of China (English)

    韩秋菊; 鲍亚丽

    2011-01-01

    [Objective] The research aimed to study separating and purifying a-galactosidase from the germinating coffee beans. [Method] By using the separation and purification technologies, such as the ammonium sulfate precipitation, DEAE-Sepharose Fast Flow anion-exchange chromatograph and Sephacryl S-200-HR gel filtration chromatograph, α-galactosidase was separated and purified from the germinating coffee beans. SDA-PAGE was used to analyze the purity and molecular weight of enzyme. [ Result] After three steps separation and purification, the specific activity of germinating coffee beans a-galactosidase reached 191.50 nkat/mg,and the purification times was 23.18. Compared with the green coffee beans a-galactosidase, the specific activity of germinating coffee beans a-galactosidase was higher,but the productive ratio and total extraction ratio were lower. SDS-PAGE analysis result showed that the enzyme had the single band, and the molecular weight was 3 8805 D. [ Conclusion ] The improvements of germinating coffee beans a-galactosidase yield and total extraction ratio needed the further research.%[目的]研究木立芦荟中黄酮类化合物的微波法提取工艺.[方法]以黄酮类化合物提取率为指标,采用单因素试验和正交试验相结合的方法,对木立芦荟中黄酮类化合物的微波法提取工艺进行优化.[结果]微波法提取黄酮类化合物的最佳工艺条件为料液比1:50,乙醇浓度80%,微波功率560 W,微波处理时间为40s.在此条件下,测得的提取率为5.604%.[结论]与乙醇浸提法相比,微波法具有提取时间短、乙醇用量低、提取效率高的优点,是芦荟黄酮类化合物的理想提取方法.

  1. The regeneration and cytology investigation of albino seedings of Aloe arborescens Mill in the test tube%木立芦荟试管白化苗的再生和细胞学研究

    Institute of Scientific and Technical Information of China (English)

    曲春香

    2004-01-01

    对UV-B辐射诱导形成的木立芦荟的试管白化苗研究结果表明,白化苗的茎段仍具有再分化的能力;继代培养的试管白化苗还具有部分修复能力,即部分叶片恢复绿色.这种修复是随机的,在继代培养第五代时,恢复率为5.37%;恢复绿色的部位也是随机的,可在维管束处,也可在维管束之间.白化苗的根尖细胞中期分裂相观察,染色体易断裂,说明DNA受到了一定的损伤.

  2. 影响木立芦荟试管快速繁殖因素的研究%The Searching of Complications in Tissue Culture of Aloe arborescens Mill

    Institute of Scientific and Technical Information of China (English)

    曲春香

    2002-01-01

    以木立芦荟的试管苗为外植体进行试管快速繁殖的研究,结果表明6-BA可以极大地提高不定芽的增殖率,但同时出现了大量的玻璃化试管苗,而且随着继代次数的增加,出现了6-BA沉积现象,玻璃化现象更加严重;不定芽的增殖系数还与接种的外植体直径的大小、切割部位等密切相关.

  3. DETERMINATION OF ALOIN AND ALOE-EMODIN IN A. ARBORESCENS MILL BY HPLC%木立芦荟中芦荟苷和芦荟大黄素的HPLC分析

    Institute of Scientific and Technical Information of China (English)

    侯冬岩; 回瑞华; 郭华; 陈宝岩; 关崇新; 朱永强

    2003-01-01

    @@ 木立芦荟是百合科芦荟属多年生肉质多浆植物,原产地南非,除具观赏价值外,还含有大量对人体有益的化学成分,它具有健胃催泻、杀菌解毒、增强内脏功能、调节内分泌系统、软化血管、降低胆固醇、利尿、抗肿瘤、抗病毒、抗过敏、抗溃疡、收敛皮肤、保湿、抑制黑色素生成及治疗烫伤、烧伤虫咬等多种药理作用[1~3].为探求木立芦荟多种药用及保健功能的内在原因,使其得到更好的开发和利用,本文对其所含的芦荟苷和芦荟大黄素进行了分析.

  4. The Observation of the Effect of Aloe Arborescens and Hone in Treating Child Prickly Heat%木立芦荟联合蜂蜜治疗小儿痱子的效果观察

    Institute of Scientific and Technical Information of China (English)

    胡丽英; 刘德淮; 邱雪凤

    2012-01-01

    目的 观察木立芦荟联合蜂蜜治疗小儿痱子的效果.方法 将88例患者分成3组,治疗组30例,对照组130例,对照组228例,3组患者按常规给予皮肤清洁护理后,治疗组用木立芦荟洗净、去皮、去刺,捣碎成汁与适量蜂蜜搅匀涂擦患处,时照组.用痱子粉涂擦患处,对照组2仅用芦荟汁涂擦患处,每日3次,连续用5d.结果 治疗组总有效率96.7%,对照组.总有效率60%,对照组2总有效率60.7%,治疗组疗效明显优于对照组(P<0.05).结论 木立芦荟联合蜂蜜综合治疗小儿痱子疗效肯定,操作简单,是治疗小儿痱子较好的方法.

  5. 木立芦荟不同叶龄叶的解剖结构和芦荟素含量的测定%Structural analysis and aloin determination in leaves of Aloe arborescens at different leaf age

    Institute of Scientific and Technical Information of China (English)

    李景原; 王太霞; 胡正海

    2002-01-01

    目的旨在揭示芦荟素在不同叶龄芦荟叶中的含量及其差异的原因.方法用高效液相色谱法测定芦荟素的含量.用半薄切片法研究叶的解剖结构.结果在同一株植物内,从上到下随着叶龄的增大,叶片维管束中的大型薄壁细胞逐渐萎缩,芦荟素的含量逐渐降低.结论研究结果为确定木立芦荟叶的最佳采收期提供了依据.

  6. 木立芦荟中芦荟苷的HPLC分析及抗氧化性能测定%Determination of Aloin in Aloe arborescens Mill by HPLC and Its Antioxidative Effect

    Institute of Scientific and Technical Information of China (English)

    侯冬岩; 回瑞华; 杨梅; 郭华; 唐蕊; 刘晓媛; 陈宝岩

    2005-01-01

    建立了木立芦荟中芦荟苷含量的高效液相色谱测定法,色谱柱:YWG C18柱(200mm×4.5 mm,5μm),流动相:甲醇-水(体积比55:45);流速:1.0mL·min-1;检测波长:225nm.结果表明:在0.0288~0.2880μg范围内芦荟苷质量与峰面积呈良好线性关系,相关系数为0.999 8,回归方程为:A=5.298×10-7m+0.005 8,回收率为102.0%,RSD为1.24%.并用流动注射化学发光法研究了木立芦荟的抗氧化性能,实验结果表明:木立芦荟具有较强的抗氧化性能.

  7. 根癌农杆菌介导库拉索芦荟遗传转化因素优化%Factors optimization for genetic transformation in Aloe arborescens mediated by Agrobacterium tumefaciens

    Institute of Scientific and Technical Information of China (English)

    潘颖南; 蒙平; 何铁光; 苏宾; 陈廷速; 李杨瑞

    2005-01-01

    以美国库拉索芦荟的横切薄片(transverse thin cell layer,tTCL)作为转化外植体,初步研究了以根癌农杆菌介导的多种因子对芦荟遗传转化的影响.结果表明:菌株EHA105比LBA4404及AGL1转化率高;除了乙酰丁香酮(acetosyringone)外,菌液的预处理和重悬液的pH值也是影响转化的主要因子;菌液的预处理和适合的蔗糖浓度对转化也有促进作用;感染时间为12~18 min,共培养的温度和时间分别以25 ℃及5 d为佳.

  8. 木立芦荟不同叶龄叶的解剖学和组织化学及其植物化学研究%Anatomy, Histochemistry and Phytochemistry of Aloe arborescens Leaves According to Leaf-age

    Institute of Scientific and Technical Information of China (English)

    李金亭; 胡正海; 高鹏

    2007-01-01

    应用植物解剖学、组织化学、荧光显微观察与植物化学技术相结合,研究了木立芦荟不同叶龄叶的解剖结构、叶绿素和类胡萝卜的含量、芦荟素的含量及其合成和贮藏结构的特点.结果表明:芦荟素由同化薄壁组织产生,叶绿体的基质为其合成场所.芦荟素细胞可能是芦荟素早期贮存的场所,随着芦荟素细胞的逐渐萎缩老化,维管束鞘细胞成为贮藏芦荟素的代替场所.同一植株的叶随着叶龄的增长,维管束的密度降低,芦荟素细胞占维管束横切面的百分比减小,同化薄壁组织细胞中的叶绿体逐步衰老、解体,芦荟素含量逐渐降低,但不同叶龄叶中叶绿体色素的含量与芦荟素含量间没有明显的相关性.

  9. Study on Extraction of Aloe Arborescens Mill Polysaccharides by Microwave Extraction Method%微波法提取木立芦荟多糖的工艺研究

    Institute of Scientific and Technical Information of China (English)

    韩秋菊; 卢生有

    2013-01-01

    采用微波法提取木立芦荟多糖,通过正交实验确定最佳提取条件为:微波功率420 W、微波时间3 min、浸提温度70℃、料液比1∶30(g∶mL),在此条件下,木立芦荟多糖的提取率达到6.05%,比热水浸提法高出35.8%.

  10. Study on physical property and chemical components of Aloe arborescens Mill in different phase%不同生长期木立芦荟的物理性质及化学组成的研究

    Institute of Scientific and Technical Information of China (English)

    冯咏梅; 王长海; 江涛; 常秀莲; 刘兆普

    2004-01-01

    分别对3年生、6年生木立芦荟全叶汁和凝胶汁的密度、pH值、粘度进行了测定,并对其化学组分进行了分析.得到了粘度随温度变化的曲线,该曲线可以用三项式很好地表达;测出了木立芦荟自上而下不同叶片的全叶汁及凝胶汁中的蛋白质、总糖及多糖的含量,从而得到了不同叶片的蛋白质和总糖、多糖的浓度变化趋势.

  11. Study on Flavonoids Extraction from Aloe Arborescens Mill.by Ultrasonic Extraction Method%超声法提取木立芦荟总黄酮的研究

    Institute of Scientific and Technical Information of China (English)

    李宁豫; 韩秋菊

    2013-01-01

    本研究以木立芦荟干粉为原料,乙醇为溶剂,采用超声法提取总黄酮.通过单因素试验和正交试验优化提取工艺,结果最佳提取条件为:超声功率70 W、超声时间25 min、乙醇浓度80%、固液比1∶30,在此条件下,提取率达到3.05%,明显高于不经过超声处理的对照组.

  12. 闽产木立芦荟多糖对小鼠免疫功能的影响%Effect of the Polysaccharide from Fujian Aloe Arborescens on Immune Function in the Immune Inhibited Mice

    Institute of Scientific and Technical Information of China (English)

    陈丹; 王瑞国; 包国荣; 张小玲; 龚碧栋

    2005-01-01

    目的研究闽产木立芦荟多糖(MAP)对小鼠免疫功能的影响.方法用环磷酰胺(CTX)建立免疫功能抑制模型小鼠,放射免疫法检测血清肿瘤坏死因子α(TNF-α)、白细胞介素2(IL-2)、免疫球蛋白G(IgG)含量.称量胸腺、脾脏湿质量,计算胸腺指数和脾指数.结果 MAP可提高免疫抑制小鼠脏器指数及TNF-α、IL-2、IgG的水平.结论 MAP具有调节小鼠免疫功能的作用.

  13. PERELIMINARY STUDY ON THE ANTI-FUNGAL ACTIVITIES AND MICROWAVE-ASSISTED EXTRACTION OF ALOE ARBORESCENS%芦荟的抑菌活性和微波协助萃取研究初报

    Institute of Scientific and Technical Information of China (English)

    韩玉芬; 王银淑; 张春香; 刘准

    2000-01-01

    微波协助提取的芦荟提取物对水稻纹枯病、苹果轮纹病、小麦赤霉病、蕃茄早疫病、花生褐斑病等5种病菌有不同程度的抑菌活性,其中芦荟表皮提取物对水稻纹枯病和小麦赤霉病抑菌率达100%.微波协助提取与常规方法比较,前者具有提取充分、省时的优点.

  14. Isolation, Purification and Analysis of the Polysaccharide of Aloe arborescens from Fujian Province%闽产木立芦荟多糖的分离纯化及初步分析

    Institute of Scientific and Technical Information of China (English)

    陈丹; 包国荣; 黄鑫; 李虹

    2002-01-01

    目的分离纯化及初步分析闽产木立芦荟中的多糖. 方法芦荟经沸水提取,醇沉,Sevage法去除蛋白质,Sephadex G-200柱色谱分离纯化,制得闽产木立芦荟多糖,以硫酸-苯酚法测定其总糖含量. 结果闽产木立芦荟多糖经紫外吸收光谱扫描具有多糖特征吸收峰,未见核酸和蛋白质吸收峰,多糖含量可达89.7%,初步分析由D-甘露糖和D-葡萄糖等单糖组成. 结论从闽产木立芦荟中可提取分离纯度较高的杂多糖.

  15. 木立芦荟叶片愈伤组织诱导过程中防褐化的研究%Study on browning control of leaf callus inducement in tissue culture of Aloe arborescens Mill.

    Institute of Scientific and Technical Information of China (English)

    李桂荣; 赵润洲; 梁玉陈

    2007-01-01

    以木立芦荟叶片作外植体,培养于附加6-BA 2.0 mg/L+2,4-D 0.5 mg/L的MS培养基上.添加不同浓度的活性炭及维生素C附加物成分,研究木立芦荟在叶片愈伤组织诱导过程中,各种附加物成分对防止褐化的影响.结果表明:活性炭和维生素C均可有效防止褐化,2.0 g/L的活性炭或0.2 g/L的维生素C能不同程度的减轻褐化,效果最好,活性炭和维生素C配合使用时,以2.0 g/L活性炭与0.1 g/L维生素C配合使用时最理想.

  16. Migration and New Media: Transnational Families and Polymedia by Mirca Madianou and Daniel Miller (Routledge, 2012

    Directory of Open Access Journals (Sweden)

    Erwin Gaspar A. Alampay

    2012-06-01

    Full Text Available In 2007, Daniel Miller presented his paper on “What is a Mobile PhoneRelationship” in the “1st Living the Information Society Conference” held inManila. In his presentation, he mentioned the work he was just embarking onwith Mirca Madianou on long-distance relationships of separated families andthe ability of different media to sustain those relationships over time (Miller,2009. He was then building on the extensive work that Parrenas (2001, 2005a,2005b had done on Filipino transnational families, and in particular, on motheringfrom a distance

  17. Migration and New Media: Transnational Families and Polymedia by Mirca Madianou and Daniel Miller (Routledge, 2012)

    OpenAIRE

    Erwin Gaspar A. Alampay

    2012-01-01

    In 2007, Daniel Miller presented his paper on “What is a Mobile PhoneRelationship” in the “1st Living the Information Society Conference” held inManila. In his presentation, he mentioned the work he was just embarking onwith Mirca Madianou on long-distance relationships of separated families andthe ability of different media to sustain those relationships over time (Miller,2009). He was then building on the extensive work that Parrenas (2001, 2005a,2005b) had done on Filipino transnational fa...

  18. JAPANESE MILLERS' PREFERENCES FOR WHEAT AND FLOUR: A STATED PREFERENCE ANALYSIS

    OpenAIRE

    Kim, Renee B.; Unterschultz, James R.; Veeman, Michele M.

    2000-01-01

    Japan imports 6.3 MMT of wheat annually and consumes almost 35 percent of this in the form of noodles. The purpose of this paper is to report on a study that evaluates the preferences of Japanese millers for the various characteristics of wheat and flour that are used in noodle making in Japan. The study used stated preference methodologies (SPM), that were developed and pre-tested through initial interviews with Japanese flour millers. In total, 57 purchase and quality managers for 22 Japane...

  19. The 1953 Stanley L. Miller Experiment: Fifty Years of Prebiotic Organic Chemistry

    Science.gov (United States)

    Lazcano, Antonio; Bada, Jeffrey L.

    2003-01-01

    The field of prebiotic chemistry effectively began with a publication in Science 50 years ago by Stanley L. Miller on the spark discharge synthesis of amino acids and other compounds using a mixture of reduced gases that were thought to represent the components of the atmosphere on the primitive Earth. On the anniversary of this landmark publication, we provide here an accounting of the events leading to the publication of the paper. We also discuss the historical aspects that lead up to the landmark Miller experiment.

  20. Efeito do gel da babosa (Aloe barbadensis Mill. associado ao ultrassom em processo inflamatório agudo Effect of aloe (Aloe barbadensis Mill. gel combined with ultrasound in the acute inflammatory process

    Directory of Open Access Journals (Sweden)

    A.L.M Maia-Filho

    2011-01-01

    Full Text Available O presente trabalho teve por objetivo analisar a ação antiinflamatória do gel da Babosa a 2% (Aloe barbadensis Mill. associado ao Ultrassom pulsátil no modelo de edema de pata. Foram utilizados 25 ratos Wistar, (200-250 g, divididos em 5 grupos de 5 animais cada. Grupo1 (controle: ratos tratados com solução salina a 0,9%; Grupo 2: ratos tratados topicamente com gel de A. barbadensis Mill. a 2%; Grupo 3: animais tratados com Ultrassom; Grupo 4: ratos tratados com gel de A. barbadensis Mill. a 2% associado ao Ultrassom; Grupo 5 (controle positivo: ratos tratados com Indometacina na dose de 5 mg Kg-1. Os animais dos grupos 1 e 5 receberam os respectivos tratamentos por via intra-peritoneal 30 minutos antes da injeção intra-plantar de carragenina e os grupos 2, 3 e 4 foram tratados por aplicação tópica de gel de A. barbadensis Mill. a 2%, Ultrassom pulsátil e gel de A. barbadensis Mill. associado ao Ultrassom respectivamente 15 minutos após a indução do edema. Os animais do grupo 04 demonstraram redução significativa do edema quando comparados ao grupo controle, ao mesmo tempo, que se mostrou comparável à indometacina. Observou-se que o gel de aloe associado à fonoforose é capaz reduzir a formação do edema de pata em ratosThis work aimed to evaluate the anti-inflammatory action of 2% aloe (Aloe barbadensis Mill. gel combined with pulsed ultrasound in the paw edema model. Twenty-five Wistar rats (200-250 g were divided into 5 groups of 5 animals each. Group1 (control: rats treated with 0.9% saline; Group 2: rats topically treated with 2% aloe gel; Group 3: rats treated with ultrasound; Group 4: rats treated with 2% aloe gel combined with ultrasound; Group 5 (positive control: rats treated with indomethacin at 5 mg Kg-1. Animals of groups 1 and 5 were intraperitoneally treated 30 min before intraplantar carrageenan injection and groups 2, 3 and 4 were treated by topical application of 2% aloe gel, pulsed ultrasound and aloe gel

  1. Protective effects of Aloe vera-based diets in Eimeria maxima-infected broiler chickens.

    Science.gov (United States)

    Yim, Dongjean; Kang, Sang S; Kim, Dong W; Kim, Sang H; Lillehoj, Hyun S; Min, Wongi

    2011-01-01

    Aloes have been widely used for a broad range of pharmacological activities, including parasitic problems. Avian coccidiosis is the most costly and wide-spread parasitic disease in the poultry industry, and has been mainly controlled by the use of chemotherapeutic agents. Due to the emergence of drug-resistant strains, alternative control strategies are needed. In this study, the protective effects of Aloe vera-based diets were assessed in broiler chickens following oral infection with Eimeria maxima. Chickens were fed a regular diet supplemented with ground Aloe vera throughout the duration of the experiment beginning 2 days prior to infection with 1 × 10(4) sporulated oocysts of E. maxima. No significant differences were found in body weight gain or loss between the Aloe vera-supplemented and unsupplemented groups with or without E. maxima infections. Fecal oocyst shedding decreased significantly (p Aloe vera as compared to the unsupplemented group. Furthermore, the Aloe vera-supplemented group showed significantly fewer intestinal lesions (p Aloe vera could be used an alternative treatment for controlling avian coccidiosis.

  2. Quality change of apple slices coated with Aloe vera gel during storage.

    Science.gov (United States)

    Song, Hye-Yeon; Jo, Wan-Shin; Song, Nak-Bum; Min, Sea C; Song, Kyung Bin

    2013-06-01

    Fresh-cut apples are easily susceptible to browning and microbial spoilage. In this study, an edible coating prepared from Aloe vera gel containing antibrowning solution was applied to preserve the quality of fresh-cut apples during storage. Fresh-cut apples were treated with both an Aloe vera gel and an Aloe vera gel containing 0.5% cysteine and then stored at 4 °C for 16 d. The color, firmness, weight loss, soluble solid content, titratable acidity, microbial analysis, and sensory evaluation were analyzed during storage. Fresh-cut apples coated with the Aloe vera gel showed delayed browning and reduced weight loss and softening compared to the control. The Aloe vera gel coating was also effective in reducing the populations of the total aerobic bacteria and yeast and molds. In particular, Aloe vera gel containing 0.5% cysteine was most effective in delaying browning and the reduction of microbial populations among the treatments. These results suggest that an Aloe vera gel coating can be used for maintaining the quality of fresh-cut apples.

  3. The efficacy of aloe vera used for burn wound healing: a systematic review.

    Science.gov (United States)

    Maenthaisong, Ratree; Chaiyakunapruk, Nathorn; Niruntraporn, Surachet; Kongkaew, Chuenjid

    2007-09-01

    Aloe vera has been traditionally used for burn healing but clinical evidence remains unclear. We conducted a systematic review to determine the efficacy of topical aloe vera for the treatment of burn wounds. We electronically searched relevant studies in MEDLINE, CINAHL, Cochrane Library, HealthSTAR, DARE, South-East Asia Database, Chinese Databases, and several Thai local Databases (1918-June 2004). Only controlled clinical trials for burn healing were included. There were no restrictions on any language of publication. Two reviewers independently extracted data on study characteristics, patient characteristics, intervention, and outcome measure. Four studies with a total of 371 patients were included in this review. Based on a meta-analysis using duration of wound healing as an outcome measure, the summary weighted mean difference in healing time of the aloe vera group was 8.79 days shorter than those in the control group (P=0.006). Due to the differences of products and outcome measures, there is paucity to draw a specific conclusion regarding the effect of aloe vera for burn wound healing. However, cumulative evidence tends to support that aloe vera might be an effective interventions used in burn wound healing for first to second degree burns. Further, well-designed trials with sufficient details of the contents of aloe vera products should be carried out to determine the effectiveness of aloe vera.

  4. Effect of Aloe barbadensis Mill. formulation on Letrozole induced polycystic ovarian syndrome rat model

    Directory of Open Access Journals (Sweden)

    Radha Maharjan

    2010-01-01

    Full Text Available This is a preliminary study that explores the efficacy of Aloe vera gel formulation as a possible therapeutic agent in the prevention and management of polycystic ovary syndrome (PCOS. PCOS is recognized as the most common endocrinopathy of women. Increased androgen synthesis, disrupted folliculogenesis, and insulin resistance lie at the patho-physiological core of PCOS. Current therapy for such a syndrome is use of insulin sensitizers. Large randomized clinical trials of metformin as the insulin-sensitizing drug, however, suggested that it produces many side effects after prolonged usage. For this reason, an alternate therapy would be to use herbs with hypoglycemic potential. Aloe barbadensis Mill. (Liliaceae popularly known as Aloe vera is a well-known plant with such properties. The present study evaluated the efficacy of Aloe vera gel formulation in a PCOS rat model. Five month old Charles Foster female rats were orally fed with letrozole, a non-steroidal aromatase inhibitor, to induce PCOS. The rats were then treated orally with the Aloe vera gel formulation (1 ml dose daily for 45 days. This restored their estrus cyclicity, glucose sensitivity, and steroidogenic activity. Co-treatment of the inductive agent (letrozole with the Aloe vera gel prevented the development of the PCO phenotype. Aloe vera gel formulation exerts a protective effect in against the PCOS phenotype by restoring the ovarian steroid status, and altering key steroidogenic activity. This can be attributed to phyto-components present in the extract.

  5. Study on the adsorptive catalytic voltammetry of aloe-emodin at a carbon paste electrode

    Institute of Scientific and Technical Information of China (English)

    LI; Ju'nan; GAO; Peng; LI; Xiangling; YAN; Zhihong; MAO; Xu

    2005-01-01

    A new catalytic voltammetric method for the determination of anthraqunone medicines at a carbon paste electrode (CPE) was described for the first time. The mechanism of the catalytic reaction was investigated by using linear sweep voltammetry, cyclic voltammetry, constant potential electrolysis and so on. The experiment results indicate that aloe-emodin was efficiently accumulated at a CPE by adsorption. In the following potential scan, aloe-emodin was reduced to homologous anthrahydroquinone compound, then the compound was immediately oxidized to aloe-emodin by the dissolved oxygen, and the aloe-emodin was again reduced at the CPE. As a result, a cyclic catalytic reaction was established. But a reversible redox reaction of aloe-emodin can only be observed at a mercury electrode, no catalytic reaction occurs there. A sensitive catalytic voltammetric peak of aloe-emodin was obtained at about -0.60 V (vs. SCE) in 0.56 mol/L NH3-NH4Cl buffer (pH 8.9). The proposed method was applied to the determination of aloe-emodin in the Radix Rhei with satisfactory results. The determination results were in good agreement with reference values obtained by the HPLC. The adsorptive catalytic voltammetry for the determination of organic compound at CPE, chemically modified electrode and other solid electrodes could be significant in the studies on pharmacology, pharmacodynamics, toxicity of medicine, clinical medicine and biochemistry.

  6. Quality change of apple slices coated with Aloe vera gel during storage.

    Science.gov (United States)

    Song, Hye-Yeon; Jo, Wan-Shin; Song, Nak-Bum; Min, Sea C; Song, Kyung Bin

    2013-06-01

    Fresh-cut apples are easily susceptible to browning and microbial spoilage. In this study, an edible coating prepared from Aloe vera gel containing antibrowning solution was applied to preserve the quality of fresh-cut apples during storage. Fresh-cut apples were treated with both an Aloe vera gel and an Aloe vera gel containing 0.5% cysteine and then stored at 4 °C for 16 d. The color, firmness, weight loss, soluble solid content, titratable acidity, microbial analysis, and sensory evaluation were analyzed during storage. Fresh-cut apples coated with the Aloe vera gel showed delayed browning and reduced weight loss and softening compared to the control. The Aloe vera gel coating was also effective in reducing the populations of the total aerobic bacteria and yeast and molds. In particular, Aloe vera gel containing 0.5% cysteine was most effective in delaying browning and the reduction of microbial populations among the treatments. These results suggest that an Aloe vera gel coating can be used for maintaining the quality of fresh-cut apples. PMID:23647574

  7. Modulation of drug efflux by aloe materials: An In Vitro investigation across rat intestinal tissue

    Directory of Open Access Journals (Sweden)

    Beneke Carien

    2013-01-01

    Full Text Available Background: Clinically, significant herb-drug interactions have been previously documented and can be pharmacodynamic and/or pharmacokinetic in nature. Pharmacokinetic interactions have been attributed to induction or inhibition of either metabolic enzymes or efflux transporters. Objective: The effect of gel and whole leaf materials from 3 different aloe species namely Aloe ferox, Aloe marlothii, and Aloe vera as well as polysaccharides precipitated from the A. vera materials on the bi-directional transport of cimetidine across rat intestinal tissue was investigated. Materials and Methods: Cimetidine transport studies were performed across excised rat intestinal tissue mounted in Sweetana-Grass diffusion chambers in both the apical-to-basolateral and basolateral-to-apical directions. Results: While A. vera gel and whole leaf materials did not inhibit the efflux of cimetidine, the polysaccharides precipitated from them did show a reduction of cimetidine efflux. On the other hand, both A. ferox and A. marlothii gel and whole leaf materials exhibited an inhibition effect on cimetidine efflux. Conclusions: This study identified a modulation effect of efflux transporters by certain aloe materials. This may cause herb-drug pharmacokinetic interactions when drugs that are substrates for these efflux transporters are taken simultaneously with aloe materials. On the other hand, these aloe materials may be used for drug absorption enhancement for drugs with low bioavailability due to extensive efflux.

  8. Binding of the bioactive component Aloe dihydroisocoumarin with human serum albumin

    Science.gov (United States)

    Zhang, Xiu-Feng; Xie, Ling; Liu, Yang; Xiang, Jun-Feng; Tang, Ya-Lin

    2008-11-01

    Aloe dihydroisocoumarin, one of new components isolated from Aloe vera, can scavenge reactive oxygen species. In order to explore the mechanism of drug action at a molecular level, the binding of Aloe dihydroisocoumarin with human serum albumin (HSA) has been investigated by using fluorescence, ultraviolet (UV), circular dichroism (CD) and Fourier transform infrared (FT-IR) spectroscopy, fluorescence dynamics, and molecular dynamic docking for the first time. We observed a quenching of fluorescence of HSA in the presence of Aloe dihydroisocoumarin and also analyzed the quenching results using the Stern-Volmer equation and obtained high affinity binding to HSA. An isoemissive point at 414 nm is seen, indicating that the quenching of HSA fluorescence depends on the formation of Aloe dihydroisocoumarin-HSA complex, which is further confirmed by fluorescence dynamic result. From the CD and FT-IR results, it is apparent that the interaction of Aloe dihydroisocoumarin with HSA causes a conformational change of the protein, with the gain of α-helix, β-sheet and random coil stability and the loss of β-turn content. Data obtained by fluorescence spectroscopy, fluorescence dynamics, CD, and FTIR experiments along with the docking studies suggest that Aloe dihydroisocoumarin binds to residues located in subdomain IIA of HSA.

  9. Inhibition Activities of Extracts from Aloe spp. with Different Solvents against Alternaria brassicae%芦荟不同溶剂提取物对白菜黑斑病菌的抑菌活性研究

    Institute of Scientific and Technical Information of China (English)

    晏卫红; 黄思良; 付岗; 岑贞陆; 谢玲

    2009-01-01

    substance based on both of the antifungal activity and yield rate. Inhibition effects of methanol, ethanol, acetone and ethyl acetate on Alternaria brassicae and dissolved activities of methanol, acetone and ethyl acetate to extracts from Aloe were tested. The results showed that different extracts from Aloe could easily dissolved in ethyl acetate and ethyl acetate had the lowest inhibition activity on Alternaria brassicae. Therefore ethyl acetate-water (7∶ 3, v/v) mixture was selected to dissolve different extracts from Aloe for further bioassay. In addition, 2 ‰-1 % Tween 20 were used as surfactant for enhancing the uniformity of the ethyl acetate-dissolved extracts in PDA plates. The inhibition rates of the extracts from 7 Aloe species on Alternaria brassicae were determined. Aloe arborescens and Aloe vera showed higher activities than the others.

  10. ANTIOXIDANT EFFECT OF ALOE VERA IN EXPERIMENTALLY INDUCED DIABETES MELLITUS

    Directory of Open Access Journals (Sweden)

    Jyoti Sethi et al

    2012-08-01

    Full Text Available The aim of the present study was to evaluate antidiabetic and antioxidant potential of Aloe vera (AV in alloxan induced diabetes in albino rabbits. Experimental Diabetes was induced in rabbits with alloxan(80mg/Kg body weightand animals showing fasting blood glucose levels more than 250mg/dl were considered as diabetics and divided into four groups of six each (n=6. Group I: Normal control rabbits, Group II: Alloxan induced diabetic rabbits, Group III: Diabetic rabbits received AV gel extract (300 mg/Kg in aqueous solution for 21 days, Group IV: diabetic rabbits given glibenclamide (600ug/kg in aqueous solution. All the drugs were administered orally (using an intra gastric tube in a single dose in the morning for 21 days. Blood samples were collected from the marginal vein of pinna of overnight fasted rabbits (Blood sugar, glycosylated hemoglobin (HbA1c, Malondialdehyde (MDA, reduced glutathione (GSH, total thiols (PSH and Superoxide dismutase (SOD. Oral administration of AV showed potent antihyperglycemic and anti-lipidperoxidative effect in diabetic animals. Simultaneously, the levels of protective antioxidant enzymes (SOD, GSH and PSH were significantly increased with AV supplementation. The results suggest potent antidiabetic and antioxidant potential of AV in experimental diabetes, and thus Aloe vera can be used as an alternative remedy for treatment of diabetes mellitus and its complications.

  11. Acemannan, an extracted polysaccharide from Aloe vera: A literature review.

    Science.gov (United States)

    Sierra-García, Gerardo Daniel; Castro-Ríos, Rocío; González-Horta, Azucena; Lara-Arias, Jorge; Chávez-Montes, Abelardo

    2014-08-01

    In this review, the composition, actions, and clinical applications of acemannan in medicine and its effectiveness as an adjunct in the treatment of diseases are presented. An electronic literature search was performed up to January 2014 for studies and research presenting data to validate the efficacy of acemannan. A total of 50 titles, abstracts and full-text studies were selected and reviewed. Acemannan has various medicinal properties like osteogenic, anti-inflammatory, and antibacterial, which accelerate healing of lesions. Also, acemannan is known to have antiviral and antitumor activities in vivo through activation of immune responses. It was concluded that Aloe vera has immense potential as a therapeutic agent. Even though the plant is a promising herb with various clinical applications in medicine and dentistry, more clinical research needs to be undertaken to validate and explain the action of acemannan in healing, so that it can be established in the field of medicine and a more precise understanding of the biological activities of these is required to develop Aloe vera as a pharmaceutical source.

  12. Acute toxicity and laxative activity of Aloe ferox resin

    Directory of Open Access Journals (Sweden)

    Vanessa R. L. Celestino

    2013-04-01

    Full Text Available Aloe ferox Mill., Xanthorrhoeaceae, resin is the solid residue obtained by evaporating the latex that drains from the leaves transversally cut. Aloe ferox has been used in folk medicine as anti-inflammatory, immunostimulant, anti-bacterial, anti-fungal, antitumor, laxative and to heal wounds and burns. The effects of the oral administration of A. ferox resin (10, 25, 50, 100 and 200 mg/kg were evaluated on intestinal transit in mice and its acute toxicity (5.0 g/kg in Wistar rats. The hydroxyanthracene derivatives present in the resin were expressed as aloin, identified by thin layer chromatography and quantified by spectrophotometry. The aloin (Rf 0.35 was identified and the percentage of hydroxyanthracene derivates expressed as aloin was 33.5%. A. ferox resin extract (50, 100 and 200 mg/kg increased the gastrointestinal motility at a 30 min interval at 93.5, 91.8 and 93.8%, respectively, when compared to control group (46.5%. A single oral dose of the A. ferox resin extract did not induce signs of toxicity or death. Thus, the results demonstrate that A. ferox has laxative activity and that it is nontoxic, since LD50 could not be estimated and it is possibly higher than 5.0 g/kg.

  13. GONÇALO M. TAVARES’S POETIC MATERIALITY

    Directory of Open Access Journals (Sweden)

    Paloma Roriz Espínola

    2015-11-01

    Full Text Available It is not rare that arquitecture opens up to dialog with literature, like it is clearly noticed with the appropriation that some writers have done with it. Such as with Paul Valery’s and João Cabral de Melo Neto’s with their recria­tion of Amphion’s myth. The anglo-portuguese writer Gonçalo M. Tavares argues on two essays, Arquitetura, natureza e amor and A estranha casa do senhor Walser, an approximation of the duties of a writer and of an arqui­tect. The purpose of this essay is to demonstrate how Gonçalo M. Tavares’ approach reflects on his body of work which is based on the search of the material aspect of language. More especifically on the poems that compose his book entitled 1, a body of work which attempts to articulate ideas with the “emotional lucidity” of Roland Barthes and the “motion” of Georges Didi-Huberman.

  14. Acemannan, an extracted polysaccharide from Aloe vera: A literature review.

    Science.gov (United States)

    Sierra-García, Gerardo Daniel; Castro-Ríos, Rocío; González-Horta, Azucena; Lara-Arias, Jorge; Chávez-Montes, Abelardo

    2014-08-01

    In this review, the composition, actions, and clinical applications of acemannan in medicine and its effectiveness as an adjunct in the treatment of diseases are presented. An electronic literature search was performed up to January 2014 for studies and research presenting data to validate the efficacy of acemannan. A total of 50 titles, abstracts and full-text studies were selected and reviewed. Acemannan has various medicinal properties like osteogenic, anti-inflammatory, and antibacterial, which accelerate healing of lesions. Also, acemannan is known to have antiviral and antitumor activities in vivo through activation of immune responses. It was concluded that Aloe vera has immense potential as a therapeutic agent. Even though the plant is a promising herb with various clinical applications in medicine and dentistry, more clinical research needs to be undertaken to validate and explain the action of acemannan in healing, so that it can be established in the field of medicine and a more precise understanding of the biological activities of these is required to develop Aloe vera as a pharmaceutical source. PMID:25233608

  15. Clinical features of Miller-Fisher syndrome (report of 3 cases)%Miller-Fisher综合征的临床特点(附3例报告)

    Institute of Scientific and Technical Information of China (English)

    靳哲; 庄建华; 杨月嫦; 徐瑾; 谢雪微; 赵忠新

    2013-01-01

    Objective To explore the clinical features of Miller-Fisher syndrome.Methods The clinical data of 3 patients with Miller-Fisher syndrome were analyzed retrospectively.Results There were one male and two female patients in this group,and the range of age was 43 to 56 years old.All the patients were acute onset,and they had antecedent respiratory symptoms.The common manifestations were double vision and unsteadiness; ptosis was in 2 cases,and distal numbness in 1 case.Bilateral ophthalmoplegia,decreased or absent tendon reflex and ataxia were in all the patients ; hypesthesia was in 2 cases,and autonomic dysfunction in 1 case.Examination of cerebrospinal fluid showed albuminocytologic dissociation in 2 cases.Electrophysiological studies showed abnormal H reflex in all the cases.Three cases had a good prognosis after being treated with high dosage of immunoglobulin.Conclusions The main manifestations of Miller-Fisher syndrome are ophthalmoplegia,decrease of tendon reflex and ataxia.And they may have sensory and autonomic symptoms.Treatment with high dosage of immunoglobulin may be effective.%目的 探讨Miller-Fisher综合征的临床特点.方法 回顾性分析3例Miller-Fisher综合征患者的临床资料.结果 本组男1例,女2例,年龄43~56岁;均急性起病,且存在前期呼吸道症状.临床表现均有复视及行走不稳,眼睑下垂2例,手足麻木1例.本组均有双侧眼肌麻痹、腱反射减弱(或消失)及共济失调征,有感觉减退2例、自主神经功能障碍1例.脑脊液检查示蛋白-细胞分离2例.神经电生理检查均有H反射异常.经大剂量丙种球蛋白静脉滴注治疗,3例患者均预后良好.结论 MFS患者以眼肌麻痹、腱反射减低及共济失调为主要表现,还可伴有感觉和自主神经的症状;大剂量免疫球蛋白治疗的效果较好.

  16. Effect of dietary aloe vera on growth and lipid peroxidation indices in rainbow trout (Oncorhynchus mykiss)

    OpenAIRE

    Golestan, Ghazale; Salati, Amir Parviz; Keyvanshokooh, Saeed; Zakeri, Mohammad; Moradian, Hossein

    2015-01-01

    Aloe vera has been used worldwide in pharmaceutical, food and cosmetic industries due to the plethora of biological activities of its constituents. This study was done to evaluate the effects of dietary aloe vera on growth and lipid peroxidation in rainbow trout (Oncorhynchus mykiss). A total number of 480 O. mykiss (mean weight 9.50 ± 0.85 g) were randomized into four experimental groups including one control and three experimental groups that aloe vera was incorporated in their diet at 0.5,...

  17. The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds

    Directory of Open Access Journals (Sweden)

    Seyyed Abbas Hashemi

    2015-01-01

    Full Text Available Treatment of wounds is very important and was subject of different investigations. In this regard, natural substance plays crucial role as complementary medicine. Various studies reported that aloe vera has useful effects on wounds especially cutaneous wounds healing. Therefore in the current review, we examined the effect of aloe vera on cutaneous wound healing and concluded that although aloe vera improves the wound healing as well as other procedures both clinically and experimentally, more studies are still needed to approve the outcomes.

  18. The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds.

    Science.gov (United States)

    Hashemi, Seyyed Abbas; Madani, Seyyed Abdollah; Abediankenari, Saied

    2015-01-01

    Treatment of wounds is very important and was subject of different investigations. In this regard, natural substance plays crucial role as complementary medicine. Various studies reported that aloe vera has useful effects on wounds especially cutaneous wounds healing. Therefore in the current review, we examined the effect of aloe vera on cutaneous wound healing and concluded that although aloe vera improves the wound healing as well as other procedures both clinically and experimentally, more studies are still needed to approve the outcomes. PMID:26090436

  19. Identity and Agonism: Tim Miller, Cornerstone, and the Politics of Community-Based Theatre.

    Science.gov (United States)

    Fletcher, John

    2003-01-01

    Contends that community-based theatre (CBT) can productively redefine the parameters of what "political performance" can mean. Draws on the work of community-based performance artist Tim Miller and on the author's experience as a dramaturg to suggest that artists and scholars must develop a revised idea of what constitutes activist democratic…

  20. Síndrome de Miller Fisher e neurite óptica: relato de caso

    Directory of Open Access Journals (Sweden)

    CARVALHO ALZIRA A. SIQUEIRA

    2000-01-01

    Full Text Available Descreve-se um caso de síndrome de Miller Fisher associada a neuropatia óptica desmielinizante bilateral, confirmada pelo exame de potencial evocado visual, sugerindo possível comprometimento do sistema nervoso central nessa síndrome.

  1. 28 CFR 79.53 - Proof of employment as a miller.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Proof of employment as a miller. 79.53 Section 79.53 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CLAIMS UNDER THE RADIATION... that the employment history for the time period indicated in records listed in paragraph (a) of...

  2. Children Exposed to Drugs in Utero: Their Scores on the Miller Assessment for Preschoolers.

    Science.gov (United States)

    Fulks, Mary-Ann L.; Harris, Susan R.

    1995-01-01

    The Miller Assessment for Preschoolers was administered to 54 children who had been prenatally exposed to drugs. Results indicated a tendency toward the lower end of the spectrum with poorer performance identified on test items measuring tactile, proprioceptive, and vestibular processing and language. (JOW)

  3. Síndrome de Miller Fisher e neurite óptica: relato de caso

    OpenAIRE

    CARVALHO ALZIRA A. SIQUEIRA; GALVÃO MARIA DE LOURDES S.; ROCHA MARIA SHEILA G.; PICCOLO ANA CLAUDIA; MAIA SOLYON C.

    2000-01-01

    Descreve-se um caso de síndrome de Miller Fisher associada a neuropatia óptica desmielinizante bilateral, confirmada pelo exame de potencial evocado visual, sugerindo possível comprometimento do sistema nervoso central nessa síndrome.

  4. Antioxidant activity of BHA, BHT and TBHQ examined with Miller's test

    Directory of Open Access Journals (Sweden)

    Karamac, M.

    1997-04-01

    Full Text Available In model experiments with the use of Miller's test to 5 ml emulsion 25, 12.5, 6.25 and 3.13µg BHA, BHT and TBHQ was added. Inhibitory ratios (IR for BHA and BHT were similar. At addition level of 6.25 and 3.13 IR for TBHQ was lower than for BHA and BHT. It is suggested that in the model studies with the use of Miller's test 25 µg BHA, BHT or TBHQ should be added to 5 ml of control sample.

    En experimentos modelos usando el test de Miller, a 5ml de emulsión se añadió 25, 12.5, 6.25 y 3.13µg de BHA, BHT y TBHQ. Las relaciones inhibitorias (IR para el BHA y BHT fueron similares. IR para TBHQ fue más baja que para BHA y BHT con niveles de adición del 6.25 y 3.13. Esto sugiere que en estudios modelos usando el test de Miller 25µg de BHA, BHT, o TBHQ deben ser añadidos a 5 ml de muestra control.

  5. Noble Gases in Nakhla and Three Nakhlites Miller Range 090030, 090032, and 090136

    Science.gov (United States)

    Nagao, K.; Haba, M. K.; Park, J.; Choi, J.; Baek, J. M.; Park, C.; Lee, J. I.; Lee, M. J.; Mikouchi, T.; Nyquist, L. E.; Herzog, G. F.; Turrin, B. D.; Lindsay, F. N.; Delaney, J. S.; Swisher, C. C., III

    2016-08-01

    Noble gas compositions of the Miller Range nakhlites release Kr and Xe with low 84Kr/132Xe of ≤1 and high 129Xe/132Xe of 1.95-2.13 at low heating temperature (300-400°C). The gases would be heavily fractionated martian atmosphere trapped in aqueously altered materials.

  6. An analytic study of applying miller cycle to reduce nox emission from petrol engine

    OpenAIRE

    Wang, Yaodong; Lin, Lin; Roskilly, Antony P.; Zeng, Shengchuo; Huang, Jincheng; He, Yunxin; Huang, Xiaodong; Huang, Huilan; Wei, Haiyan; Li, Shangping; Yang, J

    2007-01-01

    An analytic study of applying miller cycle to reduce nox emission from petrol engine correspondence: Corresponding author. Tel.: +0044 191 2223522; fax: +0044 191 2225491. (Wang, Yaodong) (Wang, Yaodong) School of Marine Science and Technology, Newcastle University - Newcastle upon Tyne--> , NE1 7RU--> - UNITED KINGDOM (Wang, Yaodong) Mechanical Engineering College, Guangxi University - Nanning--...

  7. Circuits of Spectacle: The Miller Brothers' 101 Ranch Real Wild West

    Science.gov (United States)

    Fields, Alison

    2012-01-01

    The Miller Brothers' 101 Ranch Real Wild West show ran from 1906 to 1931, outlasting the famous Buffalo Bill's Wild West show by more than a decade. From its beginnings in Oklahoma Territory, the Real Wild West show traveled national and international circuits and built a broad roster of performers, including more than 150 American Indians. During…

  8. On the Conventionality of Simultaneity and the Huygens-Fresnel-Miller Model of Wave Propagation

    CERN Document Server

    Bock, Robert D

    2016-01-01

    We identify a fundamental space-time invariance principle by combining the thesis of the conventionality of simultaneity with the Hugyens-Fresnel-Miller model of wave propagation. By following the standard gauge prescription, we show that the classical electromagnetic potentials influence the one-way speed of light.

  9. Introduction and Acclimatization of Wild Forgae-- Ⅰ. Ceratoides arborescens%野生牧草的引种驯化——Ⅰ华北驼绒藜

    Institute of Scientific and Technical Information of China (English)

    赵书元; 阿拉塔

    2012-01-01

    Ceratoides arborescend is preferred by livestock such as sheep,horses and camels because of its luxuriant foliages, abundant nutrition, rich protein and calcium. It's stem and leaf preserved well in cold season, and the characteristics of drought resistance,cold resistance, barren tolerance made it a kind of excellent xerophil semi-shrub in arid area. It's also a kind of important grass seed for building and planting in non-irrigated pasture. This paper introduces Ceratoides arborescens' exploitation and utilization, morphological characteristics, ecological types and cytology researches, growth and development, adaptation and habitats,building and planting technology,grassland management,nutritional value ;it also gives reference plants ofthe same genus as Ceratoides arborescens for extending plantation, exploitation and utilization.%华北驼绒藜枝叶繁茂,营养丰富,富含蛋白质及钙,为羊、马、骆驼等家畜所喜食。其茎叶在冷季保存良好,并具有抗旱、抗寒、耐瘠薄的特性,是干旱地区的优等半灌木饲草,也是建植灌草结合旱作草地的重要草种之一。概述了华北驼绒藜的开发利用、形态特征、生态型与细胞学研究、生长发育、适应性和生境条件、建植技术与草地管理、营养价值,并介绍了华北驼绒藜的同属植物,以期为更好地推广种植和合理开发利用华北驼绒藜提供参考。

  10. Comparative efficacy of aloe vera mouthwash and chlorhexidine on periodontal health: A randomized controlled trial

    Science.gov (United States)

    Jha, Abhishek; Bhashyam, Mamtha

    2016-01-01

    Background With introduction of many herbal medicines, dentistry has recently evidenced shift of approach for treating many inflammatory oral diseases by using such modalities. Aloe vera is one such product exhibiting multiple benefits and has gained considerable importance in clinical research recently. Aim To compare the efficacy of Aloevera and Chlorhexidine mouthwash on Periodontal Health. Material and Methods Thirty days randomized controlled trial was conducted among 390 dental students. The students were randomized into two intervention groups namely Aloe Vera (AV) chlorhexidine group (CHX) and one control (placebo) group. Plaque index and gingival index was recorded for each participant at baseline, 15 days and 30 days. The findings were than statistically analyzed, ANOVA and Post Hoc test were used. Results There was significant reduction (pAloe Vera (AV) and chlorhexidine group. Post hoc test showed significant difference (paloe Vera and placebo and chlorhexidine and placebo group. No significant difference (pAloe vera, chlorhexidine, dental plaque, gingivitis. PMID:27703614

  11. The combined effects of Aloe vera gel and silver nanoparticles on wound healing in rats

    Directory of Open Access Journals (Sweden)

    Y. Yousefpoor

    2016-01-01

    Full Text Available Objective(s: This study was aimed at investigating the synergy effects of Aloe vera gel and silver nanoparticles on the healing rate of the cutting wounds. Materials and Methods: In order to determine the concentration of silver nanoparticles in Aloe vera gel, the MBC methods were applied on the most common bacteria infecting wounds, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. The cutting wounds with Full-thickness skin were dorsally created on rats; then the rats were divided into 4 groups. The treatments groups included: mixture of Aloe vera gel and silver nanoparticles, Aloe vera gel alone and silver nanoparticles alone in addition to control groups. The treatment was carried out for 2 weeks and the size of the wound closures were measured by an image software analysis. Results:There was no significant difference (p

  12. Effects of highly purified anthraquinoid compounds from Aloe vera on sensitive and multidrug resistant leukemia cells.

    Science.gov (United States)

    Grimaudo, S; Tolomeo, M; Gancitano, R; Dalessandro, N; Aiello, E

    1997-01-01

    Folk medicine has attributed antitumor properties to preparations from Aloe vera. We have studied the effects of five purified compounds from the plant on human K562 leukemia and on its multidrug resistant (MDR) variant, K562/R. The glycosides aloin A and B, aloesin and aloeresin were devoid of antitumor activity up to 200 mu M concentrations. Only the aglycone aloe emodin produced reproducible antitumor effects, which, interestingly, were more pronounced in the MDR, P-glycoprotein overexpressing, cell line. Its IC50 was in fact 29 mu M in K562 and 10.5 mu M in K562/R. Aloe emodine caused mainly cytostasis and accumulation of the cells in the S and G(2)-M phases of the cell cycle during the first 48 h of treatment. Thereafter, massive cell death ensued. Research on the antitumor activity of compounds extracted from Aloe vera probably deserves continuation.

  13. Some biochemical effects of Aloe vera leaves on tissues in normal mice

    Directory of Open Access Journals (Sweden)

    S. A. Al-Ameen

    2010-01-01

    Full Text Available This research was carried out mainly to investigate the effects of the aqueous extract and proteinous fractions of Aloe veraleaves on cholesterol, acetycholinesterase in brain, glycogen, glutathione in liver and malonaldehyde levels in heart in normalmale albino mice. The antioxidant properties and inhibition of acetylcholine-sterase in tissue were detected. Intraperitonealadministration of Aloe vera extract in concentration of 400 mg/kg significantly decreased the levels of AchE in brain by (-88.27% and glutathione content in liver by (-35.48%, and increased the levels of glycogen in liver and malonaldehyde inheart by (22.60%, 85.50% respectively. At a concentration of 300 mg/kg Aloe vera extract significantly increased the level ofcholesterol in brain by (24.39%. These results clearly show the antioxidant property of the extract of Aloe vera leaves.

  14. Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries--a review.

    Science.gov (United States)

    Eshun, Kojo; He, Qian

    2004-01-01

    Scientific investigations on Aloe vera have gained more attention over the last several decades due to its reputable medicinal properties. Some publications have appeared in reputable Scientific Journals that have made appreciable contributions to the discovery of the functions and utilizations of Aloe--"nature's gift." Chemical analysis reveals that Aloe vera contains various carbohydrate polymers, notably glucomannans, along with a range of other organic and inorganic components. Although many physiological properties of Aloe vera have been described, it still remains uncertain as to which of the component(s) is responsible for these physiological properties. Further research needs to be done to unravel the myth surrounding the biological activities and the functional properties of A. vera. Appropriate processing techniques should be employed during the stabilization of the gel in order to affect and extend its field of utilization. PMID:15116756

  15. Processing, food applications and safety of aloe vera products: a review

    OpenAIRE

    Ahlawat, Kulveer Singh; Khatkar, Bhupender Singh

    2011-01-01

    Aloe vera is used for vigor, wellness and medicinal purposes since rigvedic times. Health benefits of aloe vera include its application in wound healing, treating burns, minimizing frost bite damage, protection against skin damage from x-rays, lung cancer, intestinal problems, increasing high density lipoprotein (HDL), reducing low density lipoprotein (LDL), reducing blood sugar in diabetics, fighting acquired immune deficiency syndrome (AIDS), allergies and improving immune system. Phytochem...

  16. Quality and Acceptability of Meat Nuggets with Fresh Aloe vera Gel

    OpenAIRE

    Rajkumar, V.; Verma, Arun K; Patra, G.; Pradhan, S.; Biswas, S.; P. Chauhan; Das, Arun K.

    2016-01-01

    Aloe vera has been used worldwide for pharmaceutical, food, and cosmetic industries due to its wide biological activities. However, quality improvement of low fat meat products and their acceptability with added Aloe vera gel (AVG) is scanty. The aim of this study was to explore the feasibility of using fresh AVG on physicochemical, textural, sensory and nutritive qualities of goat meat nuggets. The products were prepared with 0%, 2.5%, and 5% fresh AVG replacing goat meat and were analyzed f...

  17. In vitro and in vivo assessment of piroxicam incorporated Aloe vera transgel

    OpenAIRE

    Velam, Vinesha; Yalavarthi, Prasanna Raju; Sundaresan, CR; Vandana, KR; Dudala, Thushara Bindu; Kodavatikanti, Haritha; Vadlamudi, Harini Chowdary

    2013-01-01

    Background: The aim of the study was to develop piroxicam-Aloe vera gel (PAG) formulation and make a pharmacodynamic evaluation of the formulation. Materials and Methods: The gel was prepared by using carbopol 934 as gelling agent and methyl paraben as a preservative in an Aloe vera gel base. The formulated gel was also evaluated for physicochemical parameters like pH, viscosity, drug content, and in vitro diffusion assessment. Pharmacodynamic activity of the formulation was evaluated in Wist...

  18. The effect of Aloe vera leaf gel on fatty streak formation in hypercholesterolemic rabbits

    OpenAIRE

    Nasim Dana; Shaghayegh Haghjooy Javanmard; Sedigheh Asgary; Hossein Asnaashari; Narges Abdian

    2012-01-01

    Background: Atherosclerosis is a complex disease that is associated with a variety of etiologic factors such as hyperlipidemia and inflammation. Aloe vera (Liliaceae family) has been used traditionally as an anti-inflammatory drug. The aims of this survey were to define the beneficial effects of Aloe vera leaf gel on some of the atherosclerosis risk factors, and also fatty streak formation in hypercholesterolemic rabbits. Materials ans Methods : 32 white male rabbits were randomly divided int...

  19. Pharmacological attribute of Aloe vera: Revalidation through experimental and clinical studies

    OpenAIRE

    Gupta, Vinay K; Malhotra, Seema

    2012-01-01

    Aloe vera has long been used as a traditional medicine for inducing wound healing. It is a natural product that now a days is used in cosmetic industry. Benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves though there are various indications for its use. Biological activities include promotion of wound healing, antifungal activity, anti-inflammatory, anticancer and immunomodulatory. Gingival fibroblasts play an important role in or...

  20. A review on ethnopharmacological potential of Aloe vera L.

    Directory of Open Access Journals (Sweden)

    Md. Shamim Hossain

    2013-04-01

    Full Text Available In recent years, Aloe vera Linn. (Ghritokumari locally has become a subject of interest because of its beneficial effects on human health. The present ethnopharmacological review was conducted to evaluate the therapeutic properties of A. vera by scientific evidences. It belongs to the family Liliaceae, is a perennial herb with 30-60cm long juicy leaves which is found all over Bangladesh. To date, more than 75 active ingredients including aloesin, aloeemodin, acemannan, aloeride, methylchromones, flavonoids, saponin, amino acids, vitamins, and minerals have been identified from inner gel of leaves. It has antiinflammatory, antioxidant, antimicrobial, anticancer, antidiabetic, immuneboosting, and hypoglycemic properties. Daily supplementation with this is effective against stroke, heart attacks, leukemia, anemia, hypertension, AIDS, radiation burns, digestive disorders etc. This study also covers its taxonomy, distribution, morphology, and monograph. [J Intercult Ethnopharmacol 2013; 2(2.000: 113-120

  1. Interaction of aloe-emodin with human serum albumin

    Institute of Scientific and Technical Information of China (English)

    DU JinFeng; LI Ying; ZHANG Qi; YAO XiaoJun

    2007-01-01

    The presence of several high affinity binding sites on human serum albumin (HAS) makes it a possible target for many drugs. This study is designed to examine the effect of aloe-emodin on HAS by fluorescence, CD spectroscopy and molecular modeling. The results of fluorescence measurements suggested that the hydrophobic interaction was the predominant intermolecular force stabilizing the AE-HAS complex, which was in good agreement with the result of molecular modeling study. And the enthalpy change ΔH0 and the entropy change ΔS0 were calculated to be -7.041 kJ·mol-1 and 76.619 J·mol-1·K-1 according to the Van't Hoff equation. The alterations of protein secondary structure in the presence of AE in aqueous solution were quantitatively calculated from CD spectra, and the content of α-helices obviously increased.

  2. Miller-Dieker syndrome associated with duplication of 17p13.3 confirmed by fluorescence in situ hybridization (FISH)

    Energy Technology Data Exchange (ETDEWEB)

    Li, S.; Tuck-Muller, C.M.; Martinez, J.E. [Univ. of South Alabama, Mobile, AL (United States)] [and others

    1994-09-01

    Miller-Dieker syndrome is characterized by profound mental retardation, craniofacial abnormalities, and lissencephaly (smooth brain). Microscopic or submicroscopic deletions of the 17p13.3 region have been reported in Miller-Dieker patients. We report a patient with this syndrome in whom a duplication of the 17p13.3 region was detected by FISH. The 9-year-old female proband was referred because of features of Miller-Dieker syndrome: microcephaly, profound psychomotor retardation, seizures, characteristic facies, and lissencephaly shown by MRI studies. High-resolution G-banding failed to demonstrate an abnormality in chromosome 17. However, FISH analysis with the DNA probe (Oncor No. 5101) specific for Miller-Dieker region of chromosome 17p13.3 demonstrated duplication of this segment instead of the classic deletion. We know of no other report of Miller-Dieker syndrome associated with duplication of 17p13.3. The family study revealed normal chromosomes in both parents by cytogenetic and FISH analysis. Our investigation suggests that duplications, as well as deletions, of the 17p13.3 region are associated with the Miller-Dieker syndrome. The presence of deletions or duplications of the same chromosomal region in patients with features of Miller-Dieker syndrome suggests that its pathogenesis may be due to gene dosage effects.

  3. In vitro and biotransformational studies of aloe barbadensis mill

    International Nuclear Information System (INIS)

    Tissue culture technology can play an important role in the yield improvement of active ingredients of medicinal plants. In the present study, the potential of regeneration system of Aloe barbadensis along with biotransformational ability was explored. The maximum calli (5.65+-1.90; fresh weight) were induced under the dark condition on MS (Murashige and Skoog) medium supplemented with 2.0 mg/L of NAA (alpha-naphthaleneacetic acid), as compared to light. The highest number of shoots (12.725) were proliferated on MS regeneration medium, containing 1.0 mg/L of BAP (6-Benzyl Aminopurine) and 0.1 mg/L of IBA (Indole-3-Butyric Acid) incubated at 22 +- 2 degree C and 16/8 hr photoperiod provided by white fluorescent tube lights. These plantlets were then transferred onto root inducing medium and maximum number of roots (8.0 +- 0.70) with longer length (6.38 +- 0.34 cm) acquired at 1.0 mg/L of IBA within 14-20 days. The regenerated plants were shifted to green house for acclimatization. Effect of plant growth regulators and light was also assessed on callus cultures produced from conventionally propagated and in-vitro regenerated A. barbadensis plants. Biotransformation ability of Aloe barbadensis cell suspension culture was studied by incubation with (+)-adrenosterone (1), which afforded three products; D1-2-dehydroadrenosterone (2), 5a-androst-1-ene-3, 11, 17-trione (3) and 17b-hydroxyandrost-4-ene-3, 11-dione (4). These metabolites were structurally characterized on the basis of spectroscopic techniques. (author)

  4. TSS mapping using ALOS and THEOS imageries over Penang island

    Science.gov (United States)

    Sim, C. K.; Lim, H. S.; MatJafri, M. Z.; Abdullah, K.

    2013-05-01

    Environmental monitoring through the method of traditional ship sampling is time consuming and requires a high survey cost. This study uses an empirical model, based on actual water quality of total suspended solids (TSS) measurements from the Penang Strait, Malaysia to predict TSS based on optical properties of satellite digital imagery using advanced land observing satellite imagery (ALOS) and Thai earth observation system (THEOS) satellite imageries. The proposed algorithm is based on the reflectance model that is a function of the inherent optical properties of water, which can be related to its constituent's concentrations. Water samples were collected simultaneously with the airborne image acquisition and later analyzed in the laboratory. Water sample's locations were determined by using a handheld GPS. The digital numbers for each band corresponding to the sea-truth locations were extracted and then converted into radiance values and reflectance values. The reflectance values were used for calibration of the water quality algorithm. The efficiency of the proposed algorithm was investigated based on the observations of correlation coefficient (R) and root-mean-square deviations (RMS) with the sea-truth data. This algorithm was then used to map the TSS concentration over Penang, Malaysia. The TSS map was color-coded and geometrically corrected for visual interpretation. The calibrated algorithm had the R and RMS values of 0.9012 and 5.3651 mg/l respectively for ALOS data. The R and RMS values were 0.8515 and 6.2635 mg/l respectively for THEOS data. This study indicates that TSS mapping can be carried out using remote sensing technique of the satellite digital photography system over Penang, Malaysia.

  5. Hepatotherapeutic effect of Aloe vera in alcohol-induced hepatic damage.

    Science.gov (United States)

    Saka, W A; Akhigbe, R E; Ishola, O S; Ashamu, E A; Olayemi, O T; Adeleke, G E

    2011-07-15

    There is a lack of reliable hepatotherapeutic drugs in modern medicine in the management of alcohol/drug-induced liver damage. Aloe vera extract has been used in folklore medicine for its medicinal values. This study evaluates the hepatotherapeutic activity of aqueous extract of Aloe vera gel in rats. Sprague-Dawley rats were divided into three groups; the negative control, positive control and the extract-treated groups. The negative control received only distilled water daily. The positive control received alcohol, while the extract-treated group received aqueous extract of Aloe vera and alcohol. Hepatotoxicity was induced in the positive control and extract-treated rats with alcohol. The hepatotherapeutic effect was evaluated by performing an assay of the serum total bilirubin, alkaline phosphatase, aspartate and alanine transaminases and liver histopathology. Alanine transaminase activities were comparable in all groups. Alcohol treatment alone significantly (p Aloe vera extract. Histopathological examination revealed that alcohol induced hepatic damage. Aloe vera treatment maintained hepatic architecture similar to that seen in the control. This study shows that aqueous extract of Aloe vera gel is hepatotherapeutic and thus lends credence to the use of the plant in folklore medicine in the management of alcohol-induced hepatic dysfunction.

  6. [Bacteriostatic and/or bactericidal extract of Aloe vera gel on cultures of Listeria monocytogenes].

    Science.gov (United States)

    Ramírez Mérida, Luis Guillermo; Morón de Salim, Alba; Catinella, Rosangela; Castillo, Luis

    2012-03-01

    Listeria monocytogenes is a bacteria responsible for food borne diseases (FBD). The effect of Aloe vera gel extract as a possible bacteriostatic and/or bactericidal against Listeria monocytogenes, was checked by determined the minimum inhibitory concentration (MIC), the time of minimum inhibition (TMI) and minimum bactericidal concentration (MBC) solutions extract of Aloe vera gel in different concentrations on cultures of Listeria monocytogenes ATCC 7635. We applied the agar diffusion method, using solutions of extract of Aloe vera gel at concentrations of 0 to 100% for the MIC. The TMI was determined by growth curves in trypticase soy broth with an initial inoculum of Listeria monocytogenes ATCC 7635 of 108 CFU/mL in each solution. It was determined that the MIC was 10% extract of Aloe vera gel and TMI was 5 hours at concentrations of 10%, 20% and 30% of Aloe vera, while concentrations of 50, 80, 90 and 100%, the time was 8 hours. It was found that indeed the Aloe vera gel is bacteriostatic power on Listeria monocytogenes (p < 0.001), but yet, no bactericidal effect was obtained in our study.

  7. Aloe vera and Vitis vinifera improve wound healing in an in vivo rat burn wound model.

    Science.gov (United States)

    Lin, Li-Xin; Wang, Peng; Wang, Yu-Ting; Huang, Yong; Jiang, Lei; Wang, Xue-Ming

    2016-02-01

    Aloe vera and Vitis vinifera have been traditionally used as wound healing agents. The present study aimed to investigate the effects of aloe emodin and resveratrol in the burn wound healing procedure. Burn wounds are common in developed and developing countries, however, in developing countries, the incidence of severe complications is higher and financial resources are limited. The results of the present study demonstrated that neither aloe emodin or resveratrol were cytotoxic to THP-1 macrophages at concentrations of 1, 100 and 500 ng/ml. A significant increase in wound-healing activity was observed in mice treated with the aloe emodin and resveratrol, compared with those which received control treatments. The levels of IL-1β in the exudates of the burn wound area of the treated mice increased in a time-dependent manner over 7 days following burn wound injury. At 10 days post-injury, steady and progressive wound healing was observed in the control animals. The present study confirmed that increased wound healing occurs following treatment with aloe emodin,, compared with resveratrol, providing support for the use of Aloe vera plants to improve burn wound healing. PMID:26677006

  8. [Bacteriostatic and/or bactericidal extract of Aloe vera gel on cultures of Listeria monocytogenes].

    Science.gov (United States)

    Ramírez Mérida, Luis Guillermo; Morón de Salim, Alba; Catinella, Rosangela; Castillo, Luis

    2012-03-01

    Listeria monocytogenes is a bacteria responsible for food borne diseases (FBD). The effect of Aloe vera gel extract as a possible bacteriostatic and/or bactericidal against Listeria monocytogenes, was checked by determined the minimum inhibitory concentration (MIC), the time of minimum inhibition (TMI) and minimum bactericidal concentration (MBC) solutions extract of Aloe vera gel in different concentrations on cultures of Listeria monocytogenes ATCC 7635. We applied the agar diffusion method, using solutions of extract of Aloe vera gel at concentrations of 0 to 100% for the MIC. The TMI was determined by growth curves in trypticase soy broth with an initial inoculum of Listeria monocytogenes ATCC 7635 of 108 CFU/mL in each solution. It was determined that the MIC was 10% extract of Aloe vera gel and TMI was 5 hours at concentrations of 10%, 20% and 30% of Aloe vera, while concentrations of 50, 80, 90 and 100%, the time was 8 hours. It was found that indeed the Aloe vera gel is bacteriostatic power on Listeria monocytogenes (p < 0.001), but yet, no bactericidal effect was obtained in our study. PMID:23477211

  9. I teoremi di Modigliani-Miller: una pietra miliare della finanza (The theorems of Modigliani-Miller: a cornerstone of finance)

    OpenAIRE

    Marco Pagano

    2012-01-01

    The theorems of Modigliani and Miller (MM) is a cornerstone of finance for two reasons.The first is substantial and is derived from the nature of "propositions irrelevant": they identify a case in which the financial structure and dividend policy will not affect the value of firms, and in doing so give us a clear point of reference to understand instead what circumstances these decisions affect the value of firms, and why. In fact, the whole subsequent evolution of corporate finance has explo...

  10. DIVERSITY ANALYSIS OF DIFFERENT ACCESSIONS OF ALOE BARBADENSIS MILL. (SYN. ALOE VERA .L COLLECTED FROM RAJASTHAN USING RAPD MARKER SYSTEM

    Directory of Open Access Journals (Sweden)

    DINESH CHANDRA

    2014-03-01

    Full Text Available Under a survey and collection programme of National Agricultural Technology Project (NATP, various accessions of Aloe vera were collected from Rajasthan and Gujarat. In this study 10 Accessions from Rajasthan were characterized through RAPD. RAPD revealed 32.08 per cent polymorphic bands detecting 11.9% average diversity among the accessions studied. The diversity ranged from 4.3% to 20.4%. The primers like OPG-15 having high PIC value (0.346 are considered important for diversity studies, whereas, OPG-14 have highest Discrimination index (0.911 and may be used for identification of different accessions. The clustering analysis resulted in the formation of one group, only consisting of eight accessions while Nagour collections remained out of cluster. The diversity pattern did not show any correlation with the site of collection indicating that original introduction consisted of small sample size its spread was random.

  11. Effects of drying temperature and ethanol concentration on bipolar switching characteristics of natural Aloe vera-based memory devices.

    Science.gov (United States)

    Lim, Zhe Xi; Cheong, Kuan Yew

    2015-10-28

    Extracted, formulated, and processed natural Aloe vera has been used as an active layer for memory applications. The functional memory device is realized by a bottom-up structure of ITO/Aloe vera/Al in which the Aloe vera is spin-coated after mixing with different concentrations of ethanol (0-80 wt%) and subsequently dried at different temperatures (50-120 °C). From the current density-voltage measurements, the device can exhibit a reproducible bipolar switching characteristic with pure Aloe vera dried at 50 °C. It is proposed that charges are transported across the Aloe vera layer via space-charge-limited conduction (SCLC), and clusters of interstitial space formed by the functional groups of acemannans and de-esterified pectins in the dried Aloe vera contribute to the memory effect. The formation of charge traps in the Aloe vera layer is dependent on the drying temperature. The drying temperature of a memory-switching Aloe vera layer can be extended to 120 °C with the addition of appropriate amounts of ethanol. The concept of using natural Aloe vera as an active material for memory applications has been demonstrated, and the read memory window, ON/OFF ratio, and retention time are approximately 5.0 V, 10(3), and >10(4) s, respectively.

  12. IDENTIFICATION OF PHYTO-COMPONENTS AND ITS BIOLOGICAL ACTIVITIES OF ALOE VERA THROUGH THE GAS CHROMATOGRAPHY-MASS SPECTROMETRY

    Directory of Open Access Journals (Sweden)

    P.T.V Lakshmi

    2011-05-01

    Full Text Available In this study, the bioactive components of Aloe vera leaves have been evaluated using GC/MS. The chemical compositions of the n-hexane extract of Aloe vera were investigated using Perkin-Elmer Gas Chromatography–Mass Spectrometry, while the mass spectra of the compounds found in the extract was matched with the National Institute of Standards and Technology (NIST library. GC/MS analysis of n-hexane extract of Aloe vera revealed the existence of twenty six bioactive compounds. The results of this study offer a platform of using Aloe vera as herbal drug for cancer studies.

  13. Acute Bilateral Ophthalmoparesis with Pupilary Areflexical Mydriasis in Miller-Fisher Syndrome Treated with Intravenous Immunoglobulin

    Directory of Open Access Journals (Sweden)

    Theocharis Papanikolaou

    2010-01-01

    Full Text Available Miller-Fisher syndrome (MFS is a rare condition characterized by the classical triad of ophthalmoplegia, ataxia, and areflexia (Fisher, 1956. It is considered a variant of Guillain-Barré syndrome (GBS with which it may overlap, or it can occur in more limited forms. We report a case of a thirty-five-year-old male who presented with a six-day history of diplopia, following a recent chest infection. On examination, he was found to have bilateral sixth nerve palsy, bilateral fourth nerve palsy, bilateral areflexical mydriasis, ataxia and total absence of reflexes. After excluding other conditions, a diagnosis of Miller-Fisher syndrome was made. The patient was administered intravenous immunoglobulin and made an uneventful recovery.

  14. Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats

    Science.gov (United States)

    Aslam, Muhammad; Sial, Ali Akbar

    2014-01-01

    Cydonia oblonga Miller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (quince) in Wistar rats. The extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. The observed parameters were mounting frequency, assessment of mating performance, and orientation activities towards females, towards the environment, and towards self. The results showed that after administration of the extract mounting frequency and the mating performance of the rats increased highly significantly (P < 0.01). The extract also influenced the behaviour of treated animals in comparison to nontreated rats in a remarkable manner, making them more attracted to females. These effects were observed in sexually active male Wistar rats. PMID:24648836

  15. Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince on Sexual Behaviour of Wistar Rats

    Directory of Open Access Journals (Sweden)

    Muhammad Aslam

    2014-01-01

    Full Text Available Cydonia oblonga Miller (quince is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (quince in Wistar rats. The extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. The observed parameters were mounting frequency, assessment of mating performance, and orientation activities towards females, towards the environment, and towards self. The results showed that after administration of the extract mounting frequency and the mating performance of the rats increased highly significantly P<0.01. The extract also influenced the behaviour of treated animals in comparison to nontreated rats in a remarkable manner, making them more attracted to females. These effects were observed in sexually active male Wistar rats.

  16. Utilization of Lavandula angustifolia Miller extracts as naturalrepellents, pharmaceutical and industrial auxiliaries

    Directory of Open Access Journals (Sweden)

    AYOE YUSUFOGLU

    2004-01-01

    Full Text Available Essential oils, absolutes and concretes were prepared from the flowers and leaves of the plant Lavandula angustifolia Miller cultivated in the Bosphorus region of Istanbul, Turkey. The difference in the chemical composition of the mentioned extracts was investigated and compared by using a combination of capillary GC-MS with the aim of offering them as repellent, pharmaceutical and industrial auxiliaries. The IR-spectra, the yields and the physico-chemical data of the extracts were also analysed.

  17. A Neural Intellectual Decoupling Control Strategy for a Power Plant Ball Miller

    Institute of Scientific and Technical Information of China (English)

    Hong Zhou; Ming-Hui Zhong

    2005-01-01

    In this paper a multivariable decoupling control algorithm for the coal-pulverizing system of a ball miller is provided. It is based on a three-neuron control mechanism and solves the problem of long delay and strong coupling in ball mill coal pulverizing systems. Our system has been used for more than a year, the principle and equipment of which have been proved effective and profitable.

  18. A Study on Daisy Miller The Tragic Fate of the Heroine and its Reasons

    Institute of Scientific and Technical Information of China (English)

    张自勉; 王明媚; 卢德美

    2014-01-01

    Daisy Miller is an 1878 novella about an American girl by Henry James;This paper, based on the textual analysis of the novel is an effort to study the tragic fate of heroine and its reason through a comparative study of it. Two common reasons of the tragic destiny will be discussed in the paper:one, the oppressive environment;the other, the hero ’s inaction.

  19. The emergence of Miller's magic number on a sparse distributed memory.

    Directory of Open Access Journals (Sweden)

    Alexandre Linhares

    Full Text Available Human memory is limited in the number of items held in one's mind--a limit known as "Miller's magic number". We study the emergence of such limits as a result of the statistics of large bitvectors used to represent items in memory, given two postulates: i the Sparse Distributed Memory; and ii chunking through averaging. Potential implications for theoretical neuroscience are discussed.

  20. AILANTHUS ALTISSIMA (MILLER) SWINGLE: A SOURCE OF BIOACTIVE COMPOUNDS WITH ANTIOXIDANT ACTIVITY

    OpenAIRE

    Ângelo Luís,; Nuno Gil; Maria Emília Amaral,; Fernanda Domingues,; Ana Paula Coelho Duarte

    2012-01-01

    Ailanthus altissima (Miller) Swingle is a tree used in Chinese traditional medicine as a bitter aromatic drug and in the treatment of colds and gastric diseases. Previous phytochemical studies have demonstrated the presence of quassinoids in the plant, as well as indole alkaloids. The purpose of this work was to determine the phenolic, flavonoid, and total alkaloid contents of the ethanolic, methanolic, acetone, and hydroalcoholic crude extracts of A. altissima and then try to correlate them ...

  1. Review: Miller, Michelle Ann (2009, Rebellion and Reform in Indonesia – Jakarta’s Security and Autonomy Policies in Aceh

    Directory of Open Access Journals (Sweden)

    Antje Missbach

    2009-01-01

    Full Text Available Review of the monograph: Miller, Michelle Ann, Rebellion and Reform in Indonesia – Jakarta’s Security and Autonomy Policies in Aceh, London/ New York: Routledge, 2009, ISBN 13: 978-0-415-45467-4, 240 pages.

  2. A comparison of the leaf gel extracts of Aloe ferox and Aloe vera in the topical treatment of atopic dermatitis in Balb/c mice.

    Science.gov (United States)

    Finberg, M J; Muntingh, G L; van Rensburg, C E J

    2015-12-01

    Aloe vera gel is widely used in the treatment of an array of disturbances, especially skin disorders. The wound-healing effects have been attributed to its moisturizing and anti-inflammatory effects as well as its beneficial effect on the maturation of collagen. The aim of the present study is to compare the effects of topically applied extracts of Aloe ferox with that of Aloe vera on the symptoms as well as IgE levels of a mouse model of atopic dermatitis (AD). Mice were sensitized and challenged with 2,4-dinitrochlorobenzene and treated afterwards for 10 consecutive days with the gels of either A. ferox or A. vera applied topically to the affected areas. A placebo gel was used for the control mice. Blood was collected at the beginning and end of the treatment period to measure serum IgE levels. Although the gels of both the Aloe species inhibited the cutaneous inflammatory response as well as serum IgE levels in the rats, the extracts of A. ferox were superior to that of A. vera in reducing IgE levels. The gels of A. ferox and A. vera, applied topically, may be a safe and useful alternative to antihistamines and topical corticosteroids, for the treatment of patients suffering from recurring chronic AD. PMID:26510768

  3. A comparison of the leaf gel extracts of Aloe ferox and Aloe vera in the topical treatment of atopic dermatitis in Balb/c mice.

    Science.gov (United States)

    Finberg, M J; Muntingh, G L; van Rensburg, C E J

    2015-12-01

    Aloe vera gel is widely used in the treatment of an array of disturbances, especially skin disorders. The wound-healing effects have been attributed to its moisturizing and anti-inflammatory effects as well as its beneficial effect on the maturation of collagen. The aim of the present study is to compare the effects of topically applied extracts of Aloe ferox with that of Aloe vera on the symptoms as well as IgE levels of a mouse model of atopic dermatitis (AD). Mice were sensitized and challenged with 2,4-dinitrochlorobenzene and treated afterwards for 10 consecutive days with the gels of either A. ferox or A. vera applied topically to the affected areas. A placebo gel was used for the control mice. Blood was collected at the beginning and end of the treatment period to measure serum IgE levels. Although the gels of both the Aloe species inhibited the cutaneous inflammatory response as well as serum IgE levels in the rats, the extracts of A. ferox were superior to that of A. vera in reducing IgE levels. The gels of A. ferox and A. vera, applied topically, may be a safe and useful alternative to antihistamines and topical corticosteroids, for the treatment of patients suffering from recurring chronic AD.

  4. In vivo safety evaluation of UP780, a standardized composition of aloe chromone aloesin formulated with an Aloe vera inner leaf fillet.

    Science.gov (United States)

    Yimam, Mesfin; Brownell, Lidia; Jia, Qi

    2014-08-01

    Safety profiles of the aloe chromone aloesin or Aloe vera inner leaf fillet (Qmatrix) as a well tolerated entity have been reported separately. UP780, a standardized composition of aloe chromone formulated with an Aloe vera inner leaf fillet, has shown a significant beneficial effect in lowering blood glucose and improving insulin resistance in human. Here we evaluate the safety of UP780 after a repeated 14 and 90-day oral administration in CD-1 mice. UP780 was given at doses of 100mg/kg/day, 500mg/kg/day and 1000mg/kg/day to groups of 10 male and 10 female for 90days or administered by oral gavage at a dose of 2g/kg/day to groups of 5 male and 5 female for 14days. Body weight, feed consumption, hematology, clinical chemistry and histopathologic evaluation were performed. UP780 at a dose of 1000mg/kg/day or at 2000mg/kg/day produced no treatment-related toxicity or mortality. Body weight gain or feed consumption was similar between groups. There was no test article-related microscopic change. Spontaneously occurring minor changes in clinical chemistry and hematology were observed. However, these changes were limited to one sex or were not dose correlated. UP780 was well tolerated in this strain. A dose of 2000mg/kg/day was identified as the NOAEL (no-observed-adverse-effect-level).

  5. Toxicologic Assessment of a Commercial Decolorized Whole Leaf Aloe Vera Juice, Lily of the Desert Filtered Whole Leaf Juice with Aloesorb

    OpenAIRE

    Inder Sehgal; Wallace D. Winters; Michael Scott; Andrew David; Glenn Gillis; Thaya Stoufflet; Anand Nair; Konstantine Kousoulas

    2013-01-01

    Aloe vera, a common ingredient in cosmetics, is increasingly being consumed as a beverage supplement. Although consumer interest in aloe likely stems from its association with several health benefits, a concern has also been raised by a National Toxicology Program Report that a nondecolorized whole leaf aloe vera extract taken internally by rats was associated with intestinal mucosal hyperplasia and ultimately malignancy. We tested a decolorized whole leaf (DCWL) aloe vera, treated with activ...

  6. The Use of Aloe Vera Extract as a Novel Storage Media for the Avulsed Tooth

    Directory of Open Access Journals (Sweden)

    Samaneh Badakhsh

    2014-07-01

    Full Text Available Background: Tooth avulsion is one of the most severe dental traumas which most often occur in children. When immediate replantation is not possible, storage in a proper media may lead to a prolonged survival rate. Aloe Vera is a cactus like plant with green, tapered leaves that are filled with a transparent viscous gel. This medicinal plant has significant anti-inflammatory, antioxidant, antibacterial and antifungal effects. The purpose of this study was to assess the effectiveness of different concentrations of Aloe Vera extract compared to DMEM (cell culture medium and egg white. Methods: The periodontal ligament (PDL cells were cultured and certain number of cells were treated with Aloe Vera extract (in four different concentrations, egg white and culture media for 1, 3, 6, and 9 hours. Cell viability was determined by using the (3-[4, 5-dimethylthiazolyl-2]-2, 5-diphenyltetrazolium bromide assay. Moreover, One-way ANOVA and post hoc (LSD test were used for analyzing the study groups. Results: The results indicate that culture media and Aloe Vera extract (10, 30, and 50% concentration were statistically similar and significantly preserved more PDL cells compared to other experimental storage media. Conclusion: Aloe Vera 10, 30, and 50% may be recommended as a suitable storage media for avulsed teeth.

  7. Effect of dietary aloe vera on growth and lipid peroxidation indices in rainbow trout (Oncorhynchus mykiss).

    Science.gov (United States)

    Golestan, Ghazale; Salati, Amir Parviz; Keyvanshokooh, Saeed; Zakeri, Mohammad; Moradian, Hossein

    2015-01-01

    Aloe vera has been used worldwide in pharmaceutical, food and cosmetic industries due to the plethora of biological activities of its constituents. This study was done to evaluate the effects of dietary aloe vera on growth and lipid peroxidation in rainbow trout (Oncorhynchus mykiss). A total number of 480 O. mykiss (mean weight 9.50 ± 0.85 g) were randomized into four experimental groups including one control and three experimental groups that aloe vera was incorporated in their diet at 0.5, 1.0 and 2.0 g kg(-1). Trial was done for eight weeks. Then biometry and blood sampling were done. Plasma malondialdehyde, ferric reducing ability of plasma and growth index were estimated at the end of study. The results showed that aloe vera extract did not affect growth indices. Malondialdehyde was increased in the experimental group compared to the control group but ferric reducing ability of plasma showed a decrease in experimental groups (p aloe vera have adverse effects on antioxidant defense system in O. mykiss.

  8. Mechanism of Aloe Vera extract protection against UVA: shelter of lysosomal membrane avoids photodamage.

    Science.gov (United States)

    Rodrigues, Daniela; Viotto, Ana Cláudia; Checchia, Robert; Gomide, Andreza; Severino, Divinomar; Itri, Rosangela; Baptista, Maurício S; Martins, Waleska Kerllen

    2016-03-01

    The premature aging (photoaging) of skin characterized by wrinkles, a leathery texture and mottled pigmentation is a well-documented consequence of exposure to sunlight. UVA is an important risk factor for human cancer also associated with induction of inflammation, immunosuppression, photoaging and melanogenesis. Although herbal compounds are commonly used as photoprotectants against the harmful effects of UVA, the mechanisms involved in the photodamage are not precisely known. In this study, we investigated the effects of Aloe Vera (Aloe barbadensis mil) on the protection against UVA-modulated cell killing of HaCaT keratinocytes. Aloe Vera exhibited the remarkable ability of reducing both in vitro and in vivo photodamage, even though it does not have anti-radical properties. Interestingly, the protection conferred by Aloe Vera was associated with the maintenance of membrane integrity in both mimetic membranes and intracellular organelles. The increased lysosomal stability led to a decrease in lipofuscinogenesis and cell death. This study explains why Aloe Vera extracts offer protection against photodamage at a cellular level in both the UV and visible spectra, leading to its beneficial use as a supplement in protective dermatological formulations.

  9. 芦荟药理研究进展%Aloe Vera Pharmacological Research

    Institute of Scientific and Technical Information of China (English)

    刘学华; 赵红影; 严令耕; 李瑞; 潘苗苗

    2011-01-01

    分别从芦荟的生物活性与有效成分研究、外用功能的药理研究、作用机制研究、毒副作用和安全性研究5个方面进行了综述,并对芦荟外用功能研究进行了评述.芦荟具有很大的药用价值,尤其是外用治疗应用广泛,近年来芦荟产品的开发研究倍受青睐,应用范围日趋扩大,成为全世界关注的药食多用植物.%Aloe vera is a kind of Aloe ( L.) perennial evergreen. Aloe vera has big medicinal value.Especially topical therapy is widely used, more the favour of people. In recent years, our product of the pharmacological studies, made gratifying achievements. For more in-depth study of the use function,this paper aloe vera respectively from the biological activity of effective ingredients and pharmacological research, external function, mechanism, toxicity and safety of five aspects were summarized, and the function of aloe vera external research are reviewed.

  10. Review of Clinical Pharmacology of Aloe vera L. in the Treatment of Psoriasis.

    Science.gov (United States)

    Miroddi, Marco; Navarra, Michele; Calapai, Fabrizio; Mancari, Ferdinando; Giofrè, Salvatore Vincenzo; Gangemi, Sebastiano; Calapai, Gioacchino

    2015-05-01

    Aloe vera L., is a plant used worldwide as folk remedy for the treatment of various ailments, including skin disorders. Its gel is present in cosmetics, medicinal products and food supplements. Psoriasis, an immune-mediated chronic inflammatory disease, involving mainly the skin, affects about the 2-3% of general population. Conventional pharmacological treatments for psoriasis can have limited effectiveness and can cause adverse reactions. For this reason often psoriatic patients look for alternative treatments based on natural products containing Aloe vera. We conducted a systematic review of clinical trials assessing effectiveness and safety of aloe for the treatment of psoriasis. Clinical studies published in English were considered; a total of four clinical trials met inclusion criteria. Studies were also evaluated by using the Jadad scale and Consort Statement in Reporting Clinical trials of Herbal Medicine Intervention. Quality and methodological accuracy of considered studies varied considerably, and some crucial information to reproduce clinical results was missing. We conclude that administration of aloe as cutaneous treatment is generally well tolerated, as no serious side effects were reported. Results on the effectiveness of Aloe vera are contradictory; our analysis reveals the presence of methodological gaps preventing to reach final conclusions.

  11. Mechanism of Aloe Vera extract protection against UVA: shelter of lysosomal membrane avoids photodamage.

    Science.gov (United States)

    Rodrigues, Daniela; Viotto, Ana Cláudia; Checchia, Robert; Gomide, Andreza; Severino, Divinomar; Itri, Rosangela; Baptista, Maurício S; Martins, Waleska Kerllen

    2016-03-01

    The premature aging (photoaging) of skin characterized by wrinkles, a leathery texture and mottled pigmentation is a well-documented consequence of exposure to sunlight. UVA is an important risk factor for human cancer also associated with induction of inflammation, immunosuppression, photoaging and melanogenesis. Although herbal compounds are commonly used as photoprotectants against the harmful effects of UVA, the mechanisms involved in the photodamage are not precisely known. In this study, we investigated the effects of Aloe Vera (Aloe barbadensis mil) on the protection against UVA-modulated cell killing of HaCaT keratinocytes. Aloe Vera exhibited the remarkable ability of reducing both in vitro and in vivo photodamage, even though it does not have anti-radical properties. Interestingly, the protection conferred by Aloe Vera was associated with the maintenance of membrane integrity in both mimetic membranes and intracellular organelles. The increased lysosomal stability led to a decrease in lipofuscinogenesis and cell death. This study explains why Aloe Vera extracts offer protection against photodamage at a cellular level in both the UV and visible spectra, leading to its beneficial use as a supplement in protective dermatological formulations. PMID:26815913

  12. Effect of dietary aloe vera on growth and lipid peroxidation indices in rainbow trout (Oncorhynchus mykiss).

    Science.gov (United States)

    Golestan, Ghazale; Salati, Amir Parviz; Keyvanshokooh, Saeed; Zakeri, Mohammad; Moradian, Hossein

    2015-01-01

    Aloe vera has been used worldwide in pharmaceutical, food and cosmetic industries due to the plethora of biological activities of its constituents. This study was done to evaluate the effects of dietary aloe vera on growth and lipid peroxidation in rainbow trout (Oncorhynchus mykiss). A total number of 480 O. mykiss (mean weight 9.50 ± 0.85 g) were randomized into four experimental groups including one control and three experimental groups that aloe vera was incorporated in their diet at 0.5, 1.0 and 2.0 g kg(-1). Trial was done for eight weeks. Then biometry and blood sampling were done. Plasma malondialdehyde, ferric reducing ability of plasma and growth index were estimated at the end of study. The results showed that aloe vera extract did not affect growth indices. Malondialdehyde was increased in the experimental group compared to the control group but ferric reducing ability of plasma showed a decrease in experimental groups (p aloe vera have adverse effects on antioxidant defense system in O. mykiss. PMID:25992253

  13. Review of Clinical Pharmacology of Aloe vera L. in the Treatment of Psoriasis.

    Science.gov (United States)

    Miroddi, Marco; Navarra, Michele; Calapai, Fabrizio; Mancari, Ferdinando; Giofrè, Salvatore Vincenzo; Gangemi, Sebastiano; Calapai, Gioacchino

    2015-05-01

    Aloe vera L., is a plant used worldwide as folk remedy for the treatment of various ailments, including skin disorders. Its gel is present in cosmetics, medicinal products and food supplements. Psoriasis, an immune-mediated chronic inflammatory disease, involving mainly the skin, affects about the 2-3% of general population. Conventional pharmacological treatments for psoriasis can have limited effectiveness and can cause adverse reactions. For this reason often psoriatic patients look for alternative treatments based on natural products containing Aloe vera. We conducted a systematic review of clinical trials assessing effectiveness and safety of aloe for the treatment of psoriasis. Clinical studies published in English were considered; a total of four clinical trials met inclusion criteria. Studies were also evaluated by using the Jadad scale and Consort Statement in Reporting Clinical trials of Herbal Medicine Intervention. Quality and methodological accuracy of considered studies varied considerably, and some crucial information to reproduce clinical results was missing. We conclude that administration of aloe as cutaneous treatment is generally well tolerated, as no serious side effects were reported. Results on the effectiveness of Aloe vera are contradictory; our analysis reveals the presence of methodological gaps preventing to reach final conclusions. PMID:25756474

  14. Processed Aloe vera Gel Ameliorates Cyclophosphamide-Induced Immunotoxicity

    Directory of Open Access Journals (Sweden)

    Sun-A Im

    2014-10-01

    Full Text Available The effects of processed Aloe vera gel (PAG on cyclophosphamide (CP-induced immunotoxicity were examined in mice. Intraperitoneal injection of CP significantly reduced the total number of lymphocytes and erythrocytes in the blood. Oral administration of PAG quickly restored CP-induced lymphopenia and erythropenia in a dose-dependent manner. The reversal of CP-induced hematotoxicity by PAG was mediated by the functional preservation of Peyer’s patch cells. Peyer’s patch cells isolated from CP-treated mice, which were administered PAG, produced higher levels of T helper 1 cytokines and colony-stimulating factors (CSF in response to concanavalin A stimulation as compared with those isolated from CP-treated control mice. PAG-derived polysaccharides directly activated Peyer’s patch cells isolated from normal mice to produce cytokines including interleukin (IL-6, IL-12, interferon-γ, granulocyte-CSF, and granulocyte-macrophage-CSF. The cytokines produced by polysaccharide-stimulated Peyer’s patch cells had potent proliferation-inducing activity on mouse bone marrow cells. In addition, oral administration of PAG restored IgA secretion in the intestine after CP treatment. These results indicated that PAG could be an effective immunomodulator and that it could prevent CP-induced immunotoxic side effects.

  15. Phytochemical standardization of Aloe vera extract by HPTLC techniques

    Institute of Scientific and Technical Information of China (English)

    Dinesh K Patel; Kanika Patel; SP Dhanabal

    2012-01-01

    Objective: To examine the phytochemical parameters of Aloe vera (A. vera) L. which can be used as a tool for its standardization. Methods: The phytochemical analysis, solubility test, heavy metal analysis, antimicrobial study and quantitative analysis of gallic acid and berberine by HPTLC method were included in present study. Results: Phytochemical analysis revealed the presence of alkaloid, carbohydrate, tannin, steroid, triterpenoid and glycoside. Total flavonoid and phenol content was found to be 1.9% and 13.11%. Concentartion of lead, arsenic, mercury and cadmium was found to be under the limit. Total bacterial count, yeast and moulds contents were found to be under the limit whereas Escherichia coli (E. coli) and salmonella was found to be absent in the extract. Quantitative analysis through HPTLC revealed the presence of 2.74%and 0.543% w/w of berberine and gallic acid. Conclusions: The results indicate that the plant extract are rich in berberine and gallic acid implying their importance to human health. This investigation could be used as source of standard parameters which can play an important role in its standardization.

  16. Aloe vera-based formula as emollient on horses' hooves

    Directory of Open Access Journals (Sweden)

    Samuel Pereira Simonato

    2013-06-01

    Full Text Available The present study aimed at developing an Aloe vera-based formula for topical use on horse hoof and evaluating whether the treatment affects hooves growth and balance. Six healthy male horses between the ages of 3 and 17 years (12±5.25 were used, all semi-confined animals for breeding purposes. Before beginning A. vera treatment, animals underwent two trimming procedures with a 45 days-interval. After the second trimming, one of the forelimbs and one of the hindlimbs of 4 horses was weekly treated by topical application of the glycolic extract of A. vera at 20%. The contralateral limb, randomly chosen, received the extract at 50%. The hooves of the other animals were treated with propylene glycol. Treatment was done for 225 days and, during this time, animals underwent periodic trimming. Variables related to growth and balance of the hooves were measured before and after trimming. Data were analyzed using chi-square test and regression analysis at 5% significance. Growth rate of the hooves was not related to treatment. On the other hand, the 50% extract was related to the majority of the hooves in balance (p<0.05. Results suggest that a weekly topical treatment with A. vera glycolic extract does not improve the growth rate of the hooves; however, when applied at a high concentration, it improves their balance.

  17. Bio-inspired Aloe vera sponges for biomedical applications.

    Science.gov (United States)

    Silva, S S; Oliveira, M B; Mano, J F; Reis, R L

    2014-11-01

    Chemical composition and biological properties of Aloe vera (AV), a tropical plant, explain its potential use for cosmetic, nutritional and biomedical applications. AV gel present in AV leaves is rich in several compounds, nutrients and polysaccharides. This work proposes using AV gel complex structure and chemical composition, associated with freeze-drying, to produce sponges. To increase the structures stability in aqueous media, a thin coating of gellan gum (GG), was applied onto AV gel. AV-based sponges showed a heterogeneous porous formation, interconnected pores and good porosity (72-77%). The coating with a GG layer onto AV influenced the stability, swelling behavior and mechanical properties of the resulting sponges. Moreover, sponges provided the sustained release of BSA-FTIC, used as a model protein, over 3 weeks. Also, in vitro cell culture studies evidenced that sponges are not cytotoxic for a mouse fibroblast-like cell line. Therefore, developed AV-based sponges have potential use in biomedical applications. PMID:25129743

  18. Administration of dried Aloe vera gel powder reduced body fat mass in diet-induced obesity (DIO) rats.

    Science.gov (United States)

    Misawa, Eriko; Tanaka, Miyuki; Nabeshima, Kazumi; Nomaguchi, Kouji; Yamada, Muneo; Toida, Tomohiro; Iwatsuki, Keiji

    2012-01-01

    The aim of the present study was to investigate the anti-obesity effects of Aloe vera gel administration in male Sprague-Dawley (SD) rats with diet-induced obesity (DIO). SD rats at 7 wk of age were fed either a standard diet (10 kcal% fat) (StdD) or high-fat (60 kcal% fat) diet (HFD) during the experimental period. Four weeks after of HFD-feeding, DIO rats (11 wk of age) were orally administered with two doses of Aloe vera gel powder (20 and 200 mg/kg/d) for 90 d. Body weights (g) and body fat (%) of HFD fed rats were significantly higher than those of StdD-fed rats. Although a modest decrease of body weight (g) was observed with the administration of dried Aloe vera gel powder, both subcutaneous and visceral fat weight (g) and body fat (%) were reduced significantly in Aloe vera gel-treated rats. Serum lipid parameters elevated by HFD were also improved by the Aloe vera gel treatment. The oxygen consumption (VO(2)), an index of energy expenditure, was decreased in HFD-fed rats compared with that in StdD-fed rats. Administration of Aloe vera gel reversed the change in VO(2) in the HFD-fed rats. These results suggest that intake of Aloe vera gel reduced body fat accumulation, in part, by stimulation of energy expenditure. Aloe vera gel might be beneficial for the prevention and improvement of diet-induced obesity.

  19. Four new species of Aloe (Aloaceae) from Ethiopia, with notes on the ethics of describing new taxa from foreign countries

    DEFF Research Database (Denmark)

    Demissw, Sebsebe; Friis, Ib; Awas, Tesfaye;

    2011-01-01

    Subsequent to the treatment of the Aloaceae, with 38 species of Aloe, in the Flora of Ethiopia (Sebsebe Demissew & Gilbert 1997), four more species, Aloe bertemariae Sebsebe & Dioli (2000), A. friisii Sebsebe & M. G. Gilbert (2000), A. clarkei L. E. Newton (2002) and A. elkerriana Dioli & T. A. M...

  20. The effects of crude aqueous and alcohol extracts of Aloe vera on growth and abdominal viscera of suckling rats.

    Science.gov (United States)

    Beya, Wabeya; Davidson, Bruce; Erlwanger, Kennedy H

    2012-01-01

    The gastrointestinal tract of neonates is sensitive to dietary manipulations. When nursing mothers use Aloe vera, their babies are at risk of indirect exposure to Aloe vera via breast feeding or directly as health supplements. The effects of orally administered extracts of Aloe vera in unweaned rats were investigated. Six day old Sprague-Dawley rats were gavaged with aqueous or alcohol extracts of Aloe vera (low dose 50mg. kg⁻¹ or high dose 500mg. kg⁻¹) daily for eight days. All data were expressed as mean ± SD and analyzed by one way ANOVA. Pups receiving high doses of either extract had a significantly higher body mass gain than the group receiving lower dose (p Aloe vera extracts resulted in growth promotion, enhanced hepatic storage of metabolic substrates, increased ALP possibly in relation to bone growth and caused hypertrophy of the caecum of neonatal rats. These effects need to be explored further to enhance animal production and health.

  1. Effect of crosslinking in chitosan/aloe vera-based membranes for biomedical applications.

    Science.gov (United States)

    Silva, S S; Caridade, S G; Mano, J F; Reis, R L

    2013-10-15

    The positive interaction between polysaccharides with active phytochemicals found in medicinal plants may represent a strategy to create active wound dressing materials useful for skin repair. In the present work, blended membranes composed of chitosan (Cht) and aloe vera gel were prepared through the solvent casting, and were crosslinked with genipin to improve their properties. Topography, swelling, wettability, mechanical properties and in vitro cellular response of the membranes were investigated. With the incorporation of aloe vera gel into chitosan solution, the developed chitosan/aloe-based membranes displayed increased roughness and wettability; while the genipin crosslinking promoted the formation of stiffer membranes in comparison to those of the non-modified membranes. Moreover, in vitro cell culture studies evidenced that the L929 cells have high cell viability, confirmed by MTS test and calcein-AM staining. The findings suggested that both blend compositions and crosslinking affected the physico-chemical properties and cellular behavior of the developed membranes.

  2. RBF neural network prediction on weak electrical signals in Aloe vera var. chinensis

    Science.gov (United States)

    Wang, Lanzhou; Zhao, Jiayin; Wang, Miao

    2008-10-01

    A Gaussian radial base function (RBF) neural network forecast on signals in the Aloe vera var. chinensis by the wavelet soft-threshold denoised as the time series and using the delayed input window chosen at 50, is set up to forecast backward. There was the maximum amplitude at 310.45μV, minimum -75.15μV, average value -2.69μV and Aloe vera var. chinensis respectively. The electrical signal in Aloe vera var. chinensis is a sort of weak, unstable and low frequency signals. A result showed that it is feasible to forecast plant electrical signals for the timing by the RBF. The forecast data can be used as the preferences for the intelligent autocontrol system based on the adaptive characteristic of plants to achieve the energy saving on the agricultural production in the plastic lookum or greenhouse.

  3. Spectroscopic Constants of the X1Σ+ and 13Π states of AlO+

    Science.gov (United States)

    Sghaier, Onsi; Linguerri, Roberto; Mogren, Muneerah Mogren Al; Francisco, Joseph S.; Hochlaf, Majdi

    2016-08-01

    Using both standard and explicitly correlated ab initio methods in conjunction with several atomic basis sets, the ground state of AlO(X2Σ+) and the two lowest electronic states of AlO+ (1Σ+ and 3Π) are investigated. Potential energy curves for these species are mapped, which are incorporated later to solve the nuclear motion problem. Benchmark computations on AlO(X2Σ+) are used to determine the reliability of the theoretical methods and basis sets used for an accurate description of aluminum oxide compounds. The electronic ground state of AlO+ is X1Σ+, followed by the low-lying 13Π state. For both cationic electronic states, a set of spectroscopic parameters are recommended that may help in the identification of this ion in laboratory and astrophysical media. An accurate estimation of the adiabatic ionization energy of AlO, AIE = 9.70 eV, is also reported.

  4. Continuous processing of Aloe Vera juice in Reverse Osmosis integrated plant

    International Nuclear Information System (INIS)

    Membrane technology is being applied in the food and beverages industry particularly in fruit juice concentration all over the world. The major advantages are lesser use of energy, better taste of products, and recovery of pure aroma/flavor and ease of operation. The current study is focused on the experimental investigation of clarification and concentration of Aloe juice through membrane separation technique. The experimental procedure consists of Aloe gel followed by pulping, a clarification by filtration and the concentration by reverse osmosis (RO). Experimental rig was integrated with spiral wound TFM-50 membrane, pre-treatment filters, pumps, rota meter and pressure sensors. The effect of feed pressure and temperature was studied on the dynamic behavior of RO integrated plant for water removal and permeate flux. It was found that Aloe juice was concentrated at optimum pressure and temperature of 40 bar and 40 degree C, respectively. (author)

  5. [Isolation and characterization of active compounds from Aloe vera with a possible role in skin protection].

    Science.gov (United States)

    Kostálová, D; Bezáková, L; Oblozinský, M; Kardosová, A

    2004-09-01

    Aloe vera is widely used in food supplements, beverages, pharmaceuticals, and cosmetics. It has been long recognized as an effective natural remedy for its wound-healing properties and its positive influence on other inflammatory skin disorders. Major proteins and mono- and polysaccharides were identified and analysed from Aloe vera commercial extract. Molecular weight of proteins calculated from the sets of molecular weight reference standards, ranged from 70 kDa for the largest to 14 kDa for the smallest ones. IR spectral analysis of the carbohydrate fraction shows that the main carbohydrate copound is acetylated (1 --> 4)-beta-D-mannan substituated with D-galactose and D-glucose. The results have shown that proteins and polysaccharides are a necessary component in the study of biological activity of Aloe vera leaf extract. PMID:15506709

  6. Use of Aloe vera gel coating preserves the functional properties of table grapes.

    Science.gov (United States)

    Serrano, María; Valverde, Juan Miguel; Guillén, Fabian; Castillo, Salvador; Martínez-Romero, Domingo; Valero, Daniel

    2006-05-31

    Table grapes (Vitis vinifera L. cv. Crimson Seedless) were coated with Aloe vera gel according to our developed patent (SP Patent P200302937) and then stored for 35 days at 1 degrees C, and the subsequent shelf life (SL) was monitored at 20 degrees C. Uncoated clusters showed a rapid loss of functional compounds, such as total phenolics and ascorbic acid. These changes were accompanied by reduction of the total antioxidant activity (TAA) and increases in total anthocyanins, showing an accelerated ripening process. On the contrary, table grapes coated with Aloe vera gel significantly delayed the above changes, such as the retention of ascorbic acid during cold storage or SL. Consequently, Aloe vera gel coating, a simple and noncontaminating treatment, maintained the functional properties during postharvest storage of table grapes. PMID:16719510

  7. Study on Effect of Aloe Glue on Cytogenetics, Cellular Immunity and Cell Proliferation of Human Cells

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jiahua; WEN Shaluo; XIA Yun; ZHANG Lijun

    2002-01-01

    Objective To provide the scientific evidence for the exploiture of aloe resource. Methods Cytological combined determination was used to study the effect of aloe glue(0.01 ~ 0.3ml) on cytogenetics, cellular immunity and cell proliferation of human cells. Results SCE and MNR in varying dose groups had no significant differences as compared with control group( P > 0.05). LTR was significantly higher than that of control group(P < 0.005). MI was significantly higher than that of control group ( P < 0.05). M3 and PRI in highest dose group had significant differences as compared with control group (P < 0.05). Conclusion Aloe gel had no significant effect on cytogenetics. But it had activating effects on immunity and proliferation of cells.

  8. Effect of crosslinking in chitosan/aloe vera-based membranes for biomedical applications.

    Science.gov (United States)

    Silva, S S; Caridade, S G; Mano, J F; Reis, R L

    2013-10-15

    The positive interaction between polysaccharides with active phytochemicals found in medicinal plants may represent a strategy to create active wound dressing materials useful for skin repair. In the present work, blended membranes composed of chitosan (Cht) and aloe vera gel were prepared through the solvent casting, and were crosslinked with genipin to improve their properties. Topography, swelling, wettability, mechanical properties and in vitro cellular response of the membranes were investigated. With the incorporation of aloe vera gel into chitosan solution, the developed chitosan/aloe-based membranes displayed increased roughness and wettability; while the genipin crosslinking promoted the formation of stiffer membranes in comparison to those of the non-modified membranes. Moreover, in vitro cell culture studies evidenced that the L929 cells have high cell viability, confirmed by MTS test and calcein-AM staining. The findings suggested that both blend compositions and crosslinking affected the physico-chemical properties and cellular behavior of the developed membranes. PMID:23987385

  9. Chemical Analysis of a "Miller-Type" Complex Prebiotic Broth. Part I: Chemical Diversity, Oxygen and Nitrogen Based Polymers

    Science.gov (United States)

    Wollrab, Eva; Scherer, Sabrina; Aubriet, Frédéric; Carré, Vincent; Carlomagno, Teresa; Codutti, Luca; Ott, Albrecht

    2016-06-01

    In a famous experiment Stanley Miller showed that a large number of organic substances can emerge from sparking a mixture of methane, ammonia and hydrogen in the presence of water (Miller, Science 117:528-529, 1953). Among these substances Miller identified different amino acids, and he concluded that prebiotic events may well have produced many of Life's molecular building blocks. There have been many variants of the original experiment since, including different gas mixtures (Miller, J Am Chem Soc 77:2351-2361, 1955; Oró Nature 197:862-867, 1963; Schlesinger and Miller, J Mol Evol 19:376-382, 1983; Miyakawa et al., Proc Natl Acad Sci 99:14,628-14,631, 2002). Recently some of Miller's remaining original samples were analyzed with modern equipment (Johnson et al. Science 322:404-404, 2008; Parker et al. Proc Natl Acad Sci 108:5526-5531, 2011) and a total of 23 racemic amino acids were identified. To give an overview of the chemical variety of a possible prebiotic broth, here we analyze a "Miller type" experiment using state of the art mass spectrometry and NMR spectroscopy. We identify substances of a wide range of saturation, which can be hydrophilic, hydrophobic or amphiphilic in nature. Often the molecules contain heteroatoms, with amines and amides being prominent classes of molecule. In some samples we detect ethylene glycol based polymers. Their formation in water requires the presence of a catalyst. Contrary to expectations, we cannot identify any preferred reaction product. The capacity to spontaneously produce this extremely high degree of molecular variety in a very simple experiment is a remarkable feature of organic chemistry and possibly prerequisite for Life to emerge. It remains a future task to uncover how dedicated, organized chemical reaction pathways may have arisen from this degree of complexity.

  10. Comparison of the clinical applicability of Miller's classification system to Kumar and Masamatti's classification system of gingival recession

    Science.gov (United States)

    Kumar, Ashish; Gupta, Geeti; Puri, Komal; Bansal, Mansi; Jain, Deept; Khatri, Manish; Masamatti, Sujata Surendra

    2015-01-01

    Background: The aims of the present study were to (i) Find the percentage of recession cases that could be classified by application of Miller's and/or Kumar and Masamatti's classification of gingival recession, and (ii) compare the percentage of clinical applicability of Miller's criteria and Kumar and Masamatti's criteria to the total recessions present. Materials and Methods: A total of 104 patients (1089 recession cases) were included in the study wherein they were classified using both Miller's and Kumar and Masamatti's classification systems of gingival recession. Percentage comparison of the application of both classification systems was done. Results: Data analysis showed that though all the cases of the recession were classified by Kumar and Masamatti's classification, only 34.61% cases were classified by Miller's classification. 19.10% cases were completely (having only labial/buccal recession) classified. In 15.51% (out of 34.61%) cases, only buccal recession was classified according to Miller's criteria and included in this category, although these cases had both buccal and lingual/palatal recessions. Furthermore, 29.75% cases of recession with interdental loss and marginal tissue loss coronal to mucogingival junction (MGJ) remained uncategorized by Miller's classification; categorization of palatal/lingual recession was possible with Kumar and Masamatti's classification. Conclusion: The elaborative evaluation of both buccal and palatal/lingual recession by the Kumar and Masamatti's classification system can be used to overcome the limitations of Miller's classification system, especially the cases with interdental loss and having marginal tissue loss coronal to MGJ. PMID:26644724

  11. A Comparison between Antibacterial Activity of Propolis and Aloe vera on Enterococcus faecalis (an In Vitro Study).

    Science.gov (United States)

    Ehsani, Maryam; Amin Marashi, Mahmood; Zabihi, Ebrahim; Issazadeh, Maryam; Khafri, Soraya

    2013-01-01

    Removing the bacteria, including Enterococcus faecalis, from the root canal is one of the important aims in endodontic treatment.We aimed to compare the antibacterial activity of Chlorhexidine with two natural drugs. The antibacterial activities of three different propolis extracts (alcohol concentrations: 0, 15, 40%) and Aloe vera gel on E. faecalis were compared using three methods: disk diffusion, microdilution and direct contact test. In addition to the above bacterium, the Aloe vera gel effect on Staphylococcus aureus and Streptococcus mutans was evaluated. Disk diffusion test revealed that propolis ethanolic extracts (the alcohol concentration of 15 and 40%) and Aloe vera gel have antibacterial activities but aqueous extract of propolis did not show any effect in this test. The MICs for propolis ethanolic extracts, Aloe vera gel and aqueous extract of propolis (0% alcohol) were 313 µg/ml, 750 µg/ml, 2250 µg/ml, and ≥ 500 µg/ml respectively, much higher than the Chlorhexidine one. In direct contact test, contrary to Aloe vera, all three propolis extracts showed antibacterial effects on E. faecalis. The Aloe vera gel also showed significant antibacterial effect on S.aureus and S.mutans. The hydroalcoholic extracts of propolis and Aloe vera gel had antibacterial effects on E. faecalis, however, propolis is more potent than Aloe vera. The antibacterial effect of Aloe vera on S. aureus and S. mutans is low (MIC ≥ 2250 µg/ml). Appropriate concentrations of alcoholic extracts of propolis and some fractions of Aloe vera gel might be good choices for disinfecting the root canal in endodontic treatments.

  12. Therapeutic approach by Aloe vera in experimental model of multiple sclerosis.

    Science.gov (United States)

    Mirshafiey, A; Aghily, B; Namaki, S; Razavi, A; Ghazavi, A; Ekhtiari, P; Mosayebi, G

    2010-09-01

    Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that leads to an inflammatory demyelination, axonal damage, and progressive neurologic disability that affects approximately 2.5 million people worldwide. The aim of the present research was to test the therapeutic effect of Aloe vera in experimental model of MS. All experiments were conducted on C57BL/6 male mice aged 6-8 weeks. To induce the experimental autoimmune encephalomyelitis (EAE), 250 microg of the myelin oligodendrocyte glycoprotein 35-55 peptide emulsified in complete freund's adjuvant was injected subcutaneously on day 0 over two flank areas. In addition, 200 ng of pertussis toxin in 100 microL phosphate buffered saline was injected intraperitoneally on days 0 and 2. The therapeutic protocol was carried out intragastrically using 120 mg/kg/day Aloe vera from 7 days before to 21 days after EAE induction. The mice were killed 21 days after EAE induction. The brains of mice were removed for histological analysis and their isolated splenocytes were cultured. The results indicated that treatment with Aloe vera caused a significant reduction in severity of the disease in experimental model of MS. Histological analysis showed 3 +/- 2 plaques in Aloe vera-treated mice compared with 5 +/- 1 plaques in control group. The density of mononuclear infiltration in the CNS of Aloe vera-treated mice (500 +/- 200) was significantly less in comparison to 700 +/- 185 cells in control group. Moreover, the serum level of nitric oxide in treatment group was significantly less than control animals. The level of interferon-gamma in cell culture supernatant of treated mice splenocytes was lower than control group, whereas decrease in serum level of interleukin-10 in treatment group was not significant in comparison with control mice. These data indicate that Aloe vera therapy can attenuate the disease progression in experimental model of MS.

  13. Phytomodulatory potentials of Aloe vera against Salmonella OmpR-mediated inflammation.

    Science.gov (United States)

    Rishi, Praveen; Rampuria, Anjali; Tewari, Rupinder; Koul, Ashwani

    2008-08-01

    Mediators released during inflammatory response play an essential role in eliminating microbes or microbial products. However, the uncontrolled release of cytotoxic substances characterized by extensive inflammation may adversely affect normal tissues. Under such conditions it is important to manage the hyperinflammation in order to change the clinical manifestations of the disease. Accordingly, the present study was designed to evaluate the modulation of Salmonella OmpR mediated inflammation by Aloe vera, a plant known to contain antiinflammatory ingredients. It was observed that outer-membrane proteins (OMPs) extracted from the wild type strain of S. typhimurium caused inflammation of greater magnitude compared with the OMPs extracted from its mutant construct as evident from the oedema test as well as the hyperalgesic (flicking) response of the animals under experimental conditions. However, Aloe vera applied topically, administered intraperitoneally or in combination modulated the inflammatory response. The maximum effect was observed with the combined formulation indicating modulation at local as well as systemic levels. The results reveal that this modulation could be due to the potential of Aloe vera to decrease peroxidative damage via a decrease in the levels of monokines (TNF-alpha, IL-1 and IL-6) and an increase in the level of superoxide dismutase (SOD). Moreover, the presence of SOD in Aloe vera itself might be responsible for enhancing its levels in the macrophages. On the other hand, no significant change in the catalase activity was observed by Aloe vera treatment. The use of Aloe vera, therefore, seems to have a promising role in the modulation of Salmonella OmpR mediated inflammation.

  14. Human radiation studies: Remembering the early years. Oral history of radiologist Earl R. Miller, M.D., August 9 and 17, 1994

    International Nuclear Information System (INIS)

    Dr. Earl R. Miller was interviewed by representatives of US DOE Office of Human Radiation Research (OHRE). The interview covers Dr. Miller's involvement with the Manhattan Engineer District, with total body irradiation, and heavy-ion therapy. Dr. Miller's remembrances include wartime work on radiation exposure, Joe Hamilton, Neutron Therapy research, means of obtaining isotopes, consent forms, infinite laminograms, invention of a baby holder to alleviate exposure of radiological technicians in diagnostic procedures involving infants, and several personages

  15. Cytotoxicity of Aloe vera gel extracts on Allium cepa root tip cells

    OpenAIRE

    İLBAŞ, Ali İrfan; GÖNEN, Umut; YILMAZ, Semih; DADANDI, Mehmet Yaşar

    2012-01-01

    Aloe vera L. is a valuable medicinal plant and is currently used in pharmaceutical, cosmetic, and food industries worldwide. In the present study, the effect of various concentrations of Aloe vera leaf gel extracts was investigated on mitotic and phase indexes of Allium cepa L. root tip cells for 24 and 48 h durations. The EC50 value of gel extracts was found to be 20% and was used to determine the experimental concentrations. The results indicated that the mitotic index and root growth rate ...

  16. Evaluation of free radical scavenging and radioprotective efficacy of Aloe vera extract

    International Nuclear Information System (INIS)

    Radiation induced damage and lethality to the normal tissues can be partially reduced by the use of radio-protectors that lower down the damaging effects of radiation. In the present study radio-protective effect of Aloe vera extract which is rich in vitamins. It is basically cellular regenerator and therefore acts, with very positive results in many conditions. It is reported to have antioxidant, anti carcinogenic, antimicrobial and immunity stimulants properties. For the present experiment, healthy Swiss albino mice (6-8 weeks old) were selected and maintained under standard conditions of temperature and light. Aloe vera juice was fed orally at the dose rate of 0.01 m1/animal/day. The animals were divided into seven groups according to the treatment given to them i.e. given cadmium chloride solution as drinking water (group-II) or exposed to 5.0 Gy gamma radiations (group-III) or combined treatment of radiation and cadmium chloride (group-IV). The alterations in the biochemical parameters of all these group were compared with that of sham irradiated animals (group-I). The animals of experimental groups were given Aloe vera seven days prior to radiation or cadmium chloride treatment (group-V, VI and VII) respectively. All biochemical parameters of the control groups were compared with the respective experimental groups. An increase in the value of total proteins, glycogen, acid and alkaline phosphatase activity and RNA was observed up to day-14 in the non drug treated group and day-7 in the Aloe vera groups. Thereafter value declined up to day-28 without reaching to the normal. Whereas the value of cholesterol and DNA showed a decreasing trend up to day-14 in non drug treated groups and day-7 in Aloe vera treated groups. Thus it showed that cadmium and radiation produced toxic effect on kidney and Aloe vera minimize these effects. Protection offered by Aloe vera may be due to the scavenging or oxidizing free radicals. Thus it can be concluded that Aloe vera may

  17. Mineral Content and Biochemical Variables of Aloe vera L. under Salt Stress

    OpenAIRE

    Bernardo Murillo-Amador; Miguel Víctor Córdoba-Matson; Jorge Arnoldo Villegas-Espinoza; Luis Guillermo Hernández-Montiel; Enrique Troyo-Diéguez; José Luis García-Hernández

    2014-01-01

    Despite the proven economic importance of Aloe vera, studies of saline stress and its effects on the biochemistry and mineral content in tissues of this plant are scarce. The objective of this study was to grow Aloe under NaCl stress of 0, 30, 60, 90 and 120 mM and compare: (1) proline, total protein, and enzyme phosphoenolpyruvate carboxylase (PEP-case) in chlorenchyma and parenchyma tissues, and (2) ion content (Na, K, Ca, Mg, Cl, Fe, P. N, Zn, B, Mn, and Cu) in roots, stems, leaves and spr...

  18. Lee Miller à travers la Roumanie, l’appareil photo à la main (1946

    Directory of Open Access Journals (Sweden)

    Adrian-Silvan Ionescu

    2012-01-01

    Full Text Available A former model and fashion photographer turned war photographer, Lee Miller visited Romania twice, in 1938 and 1946 respectively. After her second visit she published her impressions and pictures, under the title of Roumania, in Vogue magazine. Besides the published material there are her manuscripts from The Lee Miller Achives at Farley Farm House, East Sussex, England, on which this paper is based. She crossed the border coming from Hungary in early February 1946. Heading for Sibiu her car, a Chevrolet Sedan, slipping on the ice-covered road, stopped on a snowbank far off in the ditch. While looking for help in the nearby village she and her companions left the car unguarded to discover it plundered of everything, wheels included.On a Sunday afternoon she had the privilege of being received by King Mihai I and Queen Mother Elena with whom she talked exstensively. She also took magnificent pictures with the Royal Family in the imposing Peleş Castle. At Sinaia, „the summer capital of Roumania” she had also the opportunity to portray Dinu Brătianu and Iuliu Maniu, the two elderly statesmen. Maniu was surrounded by friends and party members, among whom was young Corneliu Coposu, his private secretary.Moving to Bucharest, she met old friends such as Harri Brauner and his wife, Lena Constante, with whom she wandered through the country eight years ago. Lena and Elena Pătrășcanu, wife of Lucrețiu Pătrășcanu, Minister of Justice, have started a successful marionette theatre where Lee took nice pictures. Other were taken on the streets, with peasants, street vendors and their customers. Harri took her to a bistro where they met Maria Lătărețu, the celebrating folk singer whom Brauner recorded many times. They enjoyed her songs. Suffering from fibrositis, Lee Miller undertook a peculiar treatment in a gypsy village where the inhabitants were dancing bears trainers. She was massaged by a bear weighing about 300 pounds while Brauner took

  19. 基于Caputo导数的Miller-Ross序列导数微分方程的稳定性分析%Stability Analysis of Fractional Differential Equations with Miller-Ross Sequential Derivative in Caputo Sense

    Institute of Scientific and Technical Information of China (English)

    钱德亮; 李常品

    2012-01-01

    讨论了基于Caputo导数的Miller-Ross序列导数的分数阶微分方程的稳定性.根据Laplace变换,得到分数阶微分方程的解;应用Mittag-Leffler函数的渐近展开,讨论了方程的稳定性.分两部分:齐次方程与非齐次方程.%Stability analysis of the linear fractional differential systems with Caputo derivar tive has been well-studied, the differential system with Miller-Ross sequential derivative in Caputo sense, however, has not been investigated yet. In this paper, by using the Laplace transform and the asymptotical expansion of the Mittag-Leffler function, we derive the stability criteria of the fractional differential systems with Miller-Ross sequential fractional derivative in Caputo sense, where two cases are included: the homogenous case and the non-homogenous one.

  20. Gastroprotective and Anti-ulcer activity of Aloe vera juice, Papaya fruit juice and Aloe vera and Papaya fruit combined juice in Ethanol induced Ulcerated Rats

    OpenAIRE

    Mr. S. Gopinathan; D. Naveenraj

    2013-01-01

    Peptic ulcer is the most prevalent gastrointestinal disease. Even though a wide range of drugs are available for the treatment of peptic ulcer, but many of these do not fulfill all the requirements and have side effects. These factors have attracted researchers to investigate the natural products which have more efficacy, less side effects and less expensive for the treatment of peptic ulcer disease. In the present study the anti ulcer activity of (1) Aloe vera juice, (2) papaya fruit juice (...

  1. I teoremi di Modigliani-Miller: una pietra miliare della finanza (The theorems of Modigliani-Miller: a cornerstone of finance

    Directory of Open Access Journals (Sweden)

    Marco Pagano

    2012-04-01

    Full Text Available The theorems of Modigliani and Miller (MM is a cornerstone of finance for two reasons.The first is substantial and is derived from the nature of "propositions irrelevant": they identify a case in which the financial structure and dividend policy will not affect the value of firms, and in doing so give us a clear point of reference to understand instead what circumstances these decisions affect the value of firms, and why. In fact, the whole subsequent evolution of corporate finance has explored the consequences of removing the assumptions of MM. The second reason for the importance of the fundamental theorems of MM is methodological: they have been demonstrated with a reasoning based arbitrage, which has set a precedent not only in the area of ​​corporate finance but also in that of the determination of prices of financial securities. I teoremi di Modigliani e Miller (MM sono una pietra miliare della finanza per due ragioni. La prima è sostanziale e deriva dalla loro natura di “proposizioni di irrilevanza”: essi individuano un caso in cui la struttura finanziaria e la politica dei dividendi non influiscono sul valore delle imprese, e così facendo ci danno un chiaro punto di riferimento per capire in quali circostanze invece queste decisioni influiscono sul valore delle imprese, e perché. In effetti, l’intera evoluzione successiva della finanza aziendale ha esplorato le conseguenze della rimozione delle ipotesi di MM. La seconda ragione dell’importanza fondamentale dei teoremi di MM è di tipo metodologico: essi sono stati dimostrati con un ragionamento basato sull’arbitraggio, il che ha stabilito un precedente non solo nel campo della finanza aziendale ma anche e soprattutto in quello della determinazione dei prezzi dei titoli finanziari.  JEL Codes: G32, G35Keywords: struttura finanziaria; politica dei dividendi; valore delle imprese

  2. An in vitro and in vivo toxicologic evaluation of a stabilized aloe vera gel supplement drink in mice.

    Science.gov (United States)

    Sehgal, Inder; Winters, Wallace D; Scott, Michael; Kousoulas, Konstantine

    2013-05-01

    Aloe vera gel is increasingly consumed as a beverage dietary supplement. The purpose of this study was to determine potential toxicity of a stabilized aloe vera gel derived from the inner gel fillet and marketed as a drink. The gel juice was assessed through assays of genotoxicity in vivo and acute and subchronic toxicity in B6C3F1 mice. Aloe vera did not increase the SOS DNA repair response in Escherichia coli and at 1× and 0.25× it did not increase mutagenesis of Salmonella TA100 resulting in histidine biosynthesis. At 3 and 14days following acute exposure, male and female mice gavaged with the stabilized aloe gel had daily appearances, total body weight gain, selected organ weights, necropsy and hematology tests similar to control mice gavaged with water. After a 13-week aloe gel feed study, male and female mice evaluated by the same criteria as the acute study plus feed consumption and serum chemistry tests were found to be equivalent to control groups. These data indicate that a commercial stabilized aloe gel consumed as a beverage was not genotoxic or toxic in vivo. These results contrast with those obtained using preparations containing aloe latex phenolic compounds such as anthraquinones.

  3. A comparative study of baby immature and adult shoots of Aloe vera on UVB-induced skin photoaging in vitro.

    Science.gov (United States)

    Hwang, Eunson; Kim, Su Hyeon; Lee, Sarah; Lee, Choong Hwan; Do, Seon-Gil; Kim, Jinwan; Kim, Sun Yeou

    2013-12-01

    Ultraviolet (UV) irradiation induces photo-damage of the skin, which in turn causes depletion of the dermal extracellular matrix and chronic alterations in skin structure. Skin wrinkle formations are associated with collagen synthesis and matrix metalloproteinase (MMP) expression. The production of type I procollagen is regulated by transforming growth factor-β1 (TGF-β1) expression; the activation of MMP is also correlated with an increase of interleukin-6 (IL-6). Aloe barbadensis M. (Aloe vera) is widely used in cosmetic and pharmaceutical products. In this study, we examined whether baby aloe shoot extract (BAE, immature aloe extract), which is from the one-month-old shoots of Aloe vera, and adult aloe shoot extract (AE), which is from the four-month-old shoots of Aloe vera, have a protective effect on UVB-induced skin photoaging in normal human dermal fibroblasts (NHDFs). The effects of BAE and AE on UVB-induced photoaging were tested by measuring the levels of reactive oxygen species, MMP-1, MMP-3, IL-6, type I procollagen, and TGF-β1 after UVB irradiation. We found that NHDF cells treated with BAE after UVB-irradiation suppressed MMP-1, MMP-3, and IL-6 levels compared to the AE-treated cells. Furthermore, BAE treatment elevated type I procollagen and TGF-β1 levels. Our results suggest that BAE may potentially protect the skin from UVB-induced damage more than AE.

  4. Effect of Aloe vera on some indicators of cell damage after a period of aerobic exercise in male athletes

    Directory of Open Access Journals (Sweden)

    Barati Amir-Hosein

    2015-07-01

    Full Text Available Introduction: Aloe vera is a medicinal plant with antioxidant activity. The purpose of this study was to determine the effect of Aloe vera on some indicators of cell damage after a period of aerobic exercise in male athletes of 15-18 years old. Methods: In this clinical trial study, 20 male students with average weight of 64.85 ± 51 and height of 172.05 ± 6.4 were randomly assigned to 2 groups of Aloe vera supplement (n = 10 and placebo (n = 10. Then aerobic training was conducted for 4 weeks. The supplemented group took 3 capsules, each capsule contains 2 g of dried Aloe vera and placebo group took 3 capsules/day containing dextran after every meal. To determine the index of cell injury markers creatine kinase (CK, lactate dehydrogenase (LDH and reactive protein C (CRP were determined and blood samples were collected 24 hours before and after each test. The data were analyzed using ANOVA and independent t test. Significance level was considered as P ≤ .05. Results: The use of Aloe vera during aerobic exercise significantly reduced LDH (P = .006 in the supplement group (15% reduction compared to placebo group and CRP with 11% reduction in the supplement group compared to placebo (P = .008. There was no significant reduction in CK. Conclusion: The findings of this study showed that Aloe vera reduces cell damage and inflammation indicators. This result may reflect the role of Aloe vera as anti-inflammatory and antioxidant agent.

  5. Aloe chemical constituents and pharmacological research%芦荟的化学成分及药理作用

    Institute of Scientific and Technical Information of China (English)

    翟莲; 宋凯凯

    2014-01-01

    芦荟作为一种常见的药用植物,已越来越受到人们的关注。其为百合科植物库拉索芦荟Aloe barbadensisMil er、好望角芦荟Aloe feroxMil er或其他同属近缘植物叶的汁液浓缩干燥物,含有蒽醌类、糖类、维生素类、有机酸类等多种有效成分,具有通便泻下、抗肿瘤、抗糖尿病等多种的药理作用。%Aloe vera as a common medicinal plants, has been more and more attention. The lily family plant Aloe vera Aloe barbadensisMil er, Cape Aloe Aloe feroxMil er same relatives or other juice concentrate dried leaf material, containing anthraquinone, carbohydrate, vitamins, organic acids and other active ingredients with constipation purgative, anti-tumor, anti-diabetic and other pharmacological effects.

  6. An in vitro and in vivo toxicologic evaluation of a stabilized aloe vera gel supplement drink in mice.

    Science.gov (United States)

    Sehgal, Inder; Winters, Wallace D; Scott, Michael; Kousoulas, Konstantine

    2013-05-01

    Aloe vera gel is increasingly consumed as a beverage dietary supplement. The purpose of this study was to determine potential toxicity of a stabilized aloe vera gel derived from the inner gel fillet and marketed as a drink. The gel juice was assessed through assays of genotoxicity in vivo and acute and subchronic toxicity in B6C3F1 mice. Aloe vera did not increase the SOS DNA repair response in Escherichia coli and at 1× and 0.25× it did not increase mutagenesis of Salmonella TA100 resulting in histidine biosynthesis. At 3 and 14days following acute exposure, male and female mice gavaged with the stabilized aloe gel had daily appearances, total body weight gain, selected organ weights, necropsy and hematology tests similar to control mice gavaged with water. After a 13-week aloe gel feed study, male and female mice evaluated by the same criteria as the acute study plus feed consumption and serum chemistry tests were found to be equivalent to control groups. These data indicate that a commercial stabilized aloe gel consumed as a beverage was not genotoxic or toxic in vivo. These results contrast with those obtained using preparations containing aloe latex phenolic compounds such as anthraquinones. PMID:23376510

  7. Compensation of the detector capacitance presented to charge-sensitive preamplifiers using the Miller effect

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Inyong, E-mail: iykwon@umich.edu [University of Michigan, Ann Arbor, MI (United States); Kang, Taehoon, E-mail: thnkang@umich.edu [University of Michigan, Ann Arbor, MI (United States); Wells, Byron T., E-mail: wells@galtresearch.com [Galt LLC, Ypsilanti, MI (United States); D’Aries, Lawrence J., E-mail: lawrence.j.daries.civ@mail.mil [Picatinny Arsenal, Rockaway Township, NJ (United States); Hammig, Mark D., E-mail: hammig@umich.edu [University of Michigan, Ann Arbor, MI (United States)

    2015-06-01

    This paper describes an integrated circuit design for a modified charge-sensitive amplifier (CSA) that compensates for the effect of capacitance presented by nuclear radiation detectors and other sensors. For applications that require large area semiconductor detectors or for those semiconductor sensors derived from high permittivity materials such as PbSe, the detector capacitance can degrade the system gain and bandwidth of a front-end preamplifier, resulting in extended rise times and attenuated output voltage signals during pulse formation. In order to suppress the effect of sensor capacitance, we applied a bootstrap technique into a traditional CSA. The technique exploits the Miller effect by reducing the effective voltage difference between the two sides of a radiation detector which minimizes the capacitance presented to the differential common-source amplifier. This new configuration is successfully designed to produce effective gain even at high detector capacitance. The entire circuit, including a core CSA with feedback components and a bootstrap amplifier, are implemented in a 0.18 μm CMOS process with a 3.3 V supply voltage. - Highlights: • A modified CSA was implemented for detector capacitance compensation. • Increasing detector capacitance degrades gain and rise time. • A bootstrap amplifier exploiting the Miller effect is described. • It allows using large area radiation sensors for high radiation-interaction rates. • Intensive noise analyses show that SNR is much better with the technique.

  8. ZACK SNYDER, FRANK MILLER AND HERODOTUS: THREE TAKES ON THE 300 SPARTANS

    Directory of Open Access Journals (Sweden)

    G.N. Murray

    2012-03-01

    Full Text Available The heroic defence of the Greeks at the battle of Thermopylae in 480 BC, in particularly the 300 Spartans who stood to the last man against the much larger Persian force, prompted comic book writer and illustrator Frank Miller to retell this story from a purely Spartan perspective. This version was retold once again when director Zack Snyder created a filmed version of the graphic novel named 300. Despite the film’s achievements at the box office, it was attacked for being, amongst others, historically incorrect and ideologically biased. In the graphic novel Frank Miller tells the tale of the battle at Thermopylae through the eyes of a Spartan warrior who bore the responsibility of spreading their tale so that the Spartans’ sacrifice might compel other Greek city-states to stand together against the Persians. Therefore the graphic novel and especially the film are drenched with Spartan superiority and Persian inferiority. Despite the inaccuracies and ideological bias, there are a few moments in the graphic novel and film that are notably historically correct.

  9. How James Kept the Pace?; A Look into the Organic Unity of Daisy Miller

    Directory of Open Access Journals (Sweden)

    Sina Movaghati

    2015-12-01

    Full Text Available Many Critics believe that Henry James has set the definitive standards of modern fiction writing. Undoubtedly his groundbreaking article “The Art of fiction,” which published for the first time in 1884, has a major contribution in developing the theories of fiction writing. The term Organic Unity has derived from a major Formalist Critic, Cleanth Brooks. Both James and Brooks believed that a critic should approach a text as an organic whole. So, in this article we try to pinpoint the ideas which James and Brooks claimed in their essays and see how these ideas conform to one of James’ well-known stories, Daisy Miller. We want to observe that how James develops and shapes his story around the central theme. Furthermore, we want to investigate that are there any literary devices embedded in the text of the story which help James to deliver his fiction with artistry?Keywords: James, Cleanth Brooks, Organic Unity, The Art of Fiction, Daisy Miller

  10. Compensation of the detector capacitance presented to charge-sensitive preamplifiers using the Miller effect

    International Nuclear Information System (INIS)

    This paper describes an integrated circuit design for a modified charge-sensitive amplifier (CSA) that compensates for the effect of capacitance presented by nuclear radiation detectors and other sensors. For applications that require large area semiconductor detectors or for those semiconductor sensors derived from high permittivity materials such as PbSe, the detector capacitance can degrade the system gain and bandwidth of a front-end preamplifier, resulting in extended rise times and attenuated output voltage signals during pulse formation. In order to suppress the effect of sensor capacitance, we applied a bootstrap technique into a traditional CSA. The technique exploits the Miller effect by reducing the effective voltage difference between the two sides of a radiation detector which minimizes the capacitance presented to the differential common-source amplifier. This new configuration is successfully designed to produce effective gain even at high detector capacitance. The entire circuit, including a core CSA with feedback components and a bootstrap amplifier, are implemented in a 0.18 μm CMOS process with a 3.3 V supply voltage. - Highlights: • A modified CSA was implemented for detector capacitance compensation. • Increasing detector capacitance degrades gain and rise time. • A bootstrap amplifier exploiting the Miller effect is described. • It allows using large area radiation sensors for high radiation-interaction rates. • Intensive noise analyses show that SNR is much better with the technique

  11. Standardization of micropropgation techniques for Aloe vera: a pharmaceutically important plant.

    Science.gov (United States)

    Zakia, Shehnaz; Zahid, Najma Yousaf; Yaseen, Mehwish; Abbasi, Nadeem Akhtar; Hafiz, Ashfaq Ahmad; Mahmood, Nasir

    2013-11-01

    Aloe vera (Syn Aloe barbadensis Mill.), a medicinal plant, has a great potential in cosmetic and drug industry due to presence of more than 200 bioactive compounds. Natural propagation of Aloe vera, by means of suckers, is very slow and insufficient to meet the increasing demand of pharmaceutical and cosmetic industries. Shoot tip was used as an explant for in vitro regeneration of Aloe vera. Explants were disinfested with the use of 0.1% mercuric chloride and 0.5% sodium hypochlorite, and washed thoroughly with autoclaved distilled water. Solid MS medium was used with addition of different concentrations of 6-benzyl aminopurine and α-naphthalene acitic acid. After 7 weeks of inoculation, greatest number of shoots (11.18) and highest shoot length (12.15cm) were found in MS medium supplemented with 0.5 mg l-1 6-benzylaminopurine (BAP) along with same concentration of α-naphthalene acitic acid (NAA). Best rooting (84.67%) was found in medium supplemented with 1.5 mg l-1 of indole butyric acid (IBA). The rooted explants were then gradually acclimatized and shifted to green house.

  12. Immunostimulatory and protective effects of Aloe vera against coccidiosis in industrial broiler chickens.

    Science.gov (United States)

    Akhtar, Masood; Hai, Abdul; Awais, Mian Muhammad; Iqbal, Zafar; Muhammad, Faqir; ul Haq, Ahsan; Anwar, Muhammad Irfan

    2012-05-25

    This paper reports the immunostimulatory and protective effects of Aloe vera extracts (aqueous and ethanolic) against coccidiosis in industrial broiler chickens. The study was divided into two experiments. Experiment-I was conducted for the evaluation of immunostimulatory activity of A. vera and experiment-II demonstrated the protective efficacy of A. vera extracts against coccidiosis in chickens. Results of the experiment-I revealed significantly higher (pvera as compared to those administered with aqueous extract and control group. Microplate haemagglutination assay for humoral response on day 7th and 14th post primary and secondary injections of sheep red blood cells (SRBCs) revealed significantly higher (pAloe extract as compared to the ethanolic extract administered chickens (45%). Mean oocysts per gram of droppings in the control group was significantly higher (pAloe extract showed a minimal mean lesion score (2.3) followed by those administered with ethanolic Aloe extract (2.6) and control chickens (3.05) for caeca, and a similar pattern was observed for intestinal lesion scoring. Further, significantly higher weight gains and antibody titers (pvera extracts as compared to those in the control group. It was concluded that A. vera may be a potential and valuable candidate to stimulate the immune responses and can be used successfully as an immunotherapeutic agent against coccidiosis in industrial broiler chickens.

  13. Characterization of mangrove forest types based on ALOS-PALSAR in overall Indonesian archipelago

    International Nuclear Information System (INIS)

    Indonesia has largest mangrove forest in the world, total area around 3.5 million ha or 17% – 23% from mangrove forest in the world. Mangrove forest provides products and services, such as carbon balance of the coastal zone. Mapping and monitoring biomass of mangrove is very important but field survey of mangrove biomass and productivity in overall Indonesia is very difficult. Global-scale mosaics with HH and HV backscatter of Advanced Land Observing Satellite (ALOS) Phased Array L-band Synthetic Aperture Radar (PALSAR) which is 50-m spatial resolution has been generated. This image available for identification and monitoring mangrove forest. The Objective of this research to investigate characterization of mangrove forest types based on ALOS-PALSAR in overall Indonesian archipelago. Methodology consists of collecting ALOS-PALSAR image for overall Indonesian archipelago, preprocessing and mosaicking, collecting region of interest of mangrove forest, plotting, ground survey, characterization and classification. The result of this research has showed characterization of mangrove forest types based on ALOS-PALSAR. Indonesian mangrove forest types has HH value around -10 dB until -7 dB and HV value around -17 dB until -13 dB. Higher of HH and HV backscatters value indicated higher of level biomass. Based on scatter plot of HH and HV, Indonesian mangrove forest can be classified in three level biomass. Generally level biomass of mangrove forest in Indonesia archipelago is moderate

  14. Effects of Aloe vera on dressing percentage and haemato-biochemidal parameters of broiler chickens

    Directory of Open Access Journals (Sweden)

    Jagmohan Singh

    2013-09-01

    Full Text Available Aim: To evaluate the effects of Aloe vera on dressing percentage and hemato-biochemical parameters of broiler chickens.Materials and Methods: A total of 90 chicks were used in this study. They were randomly allocated into 3 treatment groups.Fresh Aloe vera leaf juice (ALJ was prepared and administered to the test group T3 at the rate of 20 g/Lin drinking water daily.This study was carried out for 42 days. Dressing percentage and hemato-biochemical parameters were recorded at the end ofexperiment.Results: Group that was given Aloe vera (T3 showed numerically higher dressing percentage as compared to control group(T1 and drug control group (T2. It also showed significantly (P0.05 differences were observed in other parameters among all the treatment groups.Conclusion: Aloe vera has potential to be a growth promoter in broiler chicks and its growth promoting effects are comparableto that of antibiotic growth promoter (AGP.

  15. Expression of biologically active human interferon alpha 2 in aloe vera

    Science.gov (United States)

    We have developed a system for transgenic expression of proteins in Aloe Vera. Using this approach we have generated plants expressing the human gene interferon alpha 2, IFNa2. IFNa2 is a small secreted cytokine that plays a vital role in regulating the body’s immune response to viral infections a...

  16. Aloe vera for prevention of radiation-induced dermatitis: a self-controlled clinical trial.

    Science.gov (United States)

    Haddad, P; Amouzgar-Hashemi, F; Samsami, S; Chinichian, S; Oghabian, M A

    2013-08-01

    To evaluate an Aloe vera lotion for prevention of radiation-induced dermatitis, all patients with a prescription of radiotherapy to a minimum dose of 40 Gy were eligible provided that their treatment area could be divided into two symmetrical halves. Patients were given a lotion of Aloe vera to use on one half of the irradiated area, with no medication to be used on the other half. The grade of dermatitis in each half was recorded weekly until 4 weeks after the end of radiotherapy. The trial enrolled 60 patients (mean age: 52 years; 67% women). Most patients had breast cancer (38%), followed by pelvic (32%), head-and-neck (22%), and other cancers (8%). Field size was 80-320 cm(2) (mean: 177 cm(2)), and the dose of radiotherapy was 40-70 Gy (mean: 54 Gy). Concurrent chemotherapy was administered in 20 patients. From week 4 to week 6 of radiotherapy and then at weeks 2 and 4 after radiotherapy, the mean grade of dermatitis with and without Aloe vera was 0.81 and 1.10 (p Aloe vera reduces the intensity of radiationinduced dermatitis.

  17. Economic Sustainability of Organic Aloe Vera Farming in Greece under Risk and Uncertainty

    Directory of Open Access Journals (Sweden)

    Angelos Liontakis

    2016-04-01

    Full Text Available During the last decade, an encouraging environment for the restructuring and modernization of the agricultural sector has formed in Greece. The diversification into higher-value crops can be a promising option for small and average-sized farms, particularly during the current economic crisis. One of the most promising alternative crops that have been recently established in Greece is the organic Aloe vera crop. The main advantage of this crop is that it can utilize poor farmlands and, therefore, can facilitate rural development in marginal areas. This study explores the economic sustainability of the Aloe vera crop, considering the embedded risk and uncertainty. The results indicate that organic aloe farming is a promising alternative to “traditional” crops in Greece, particularly for family farms in rural areas. In contrast, this activity is not advisable to the most entrepreneurial type of farmers, unless their crop size allows economies of scales. Finally, the Stochastic Efficiency with Respect to a Function (SERF analysis associates farmers’ risk attitude with their willingness to be involved in organic Aloe vera farming. SERF analysis highlights the crucial role of farmers’ risk aversion and concludes that, above a certain level of risk aversion, farmers have no incentive to adopt this economic activity.

  18. Disinfection of dental unit water line using aloe vera: in vitro study.

    Science.gov (United States)

    Pareek, Sonia; Nagaraj, Anup; Sharma, Prateek; Atri, Mansi; Walia, Satinder; Naidu, Shravani; Yousuf, Asif

    2013-01-01

    Context. Dental unit waterlines may be heavily contaminated with microorganisms and are a potential source of infection for both practicing staff and immunocompromised patients particularly. Contamination of dental unit water lines could be inhibited with the use of disinfectants. The present study investigates the effect of aloe-vera-based disinfectant in reducing the microbial growth in dental unit water lines (DUWLs). Aims. To compare the efficacy of aloe vera, hydrogen peroxide (H2O2), and 5% sodium hypochlorite (NaOCl) in controlling microbial contamination of DUWLs. Materials and Methods. After obtaining baseline water samples, the dental unit waterlines were treated with aloe vera, 10% hydrogen peroxide, and 5% sodium hypochlorite. Each of the three disinfectants was used in increasing concentrations and their inhibiting effect was compared. Water samples were analyzed for microbiological quality by the total viable count (TVC) method. Statistical Analysis Used. SPSS 16. Results. There was significant reduction in mean CFU/ml when treated with disinfectants each for a period of one week. Aloe-vera solution was found to be the most effective in reducing the microbial colonies. Conclusions. Improving the water quality from dental unit water lines is of considerable importance; chemical-based disinfectants can be replaced with herbal disinfectants for treating microbial contamination in dental unit waterlines.

  19. Protective effects of Aloe vera-based diets in Eimeria maxima-infected broiler chickens

    Science.gov (United States)

    Aloes have been widely used for a broad range of pharmacological activities, including parasitic problems. Avian coccidiosis is the most costly and wide-spread parasitic disease in the poultry industry, and has been mainly controlled by the use of chemotherapeutic agents. Due to the emergence of dru...

  20. Facile fabrication of aloe vera containing PCL nanofibers for barrier membrane application.

    Science.gov (United States)

    Carter, Princeton; Rahman, Shekh M; Bhattarai, Narayan

    2016-01-01

    Guided tissue regeneration (GTR) is a widely used method in dental surgical procedures that utilizes a barrier membrane to exclude migration of epithelium and ensure repopulation of periodontal ligament cells at the sites having insufficient gingiva. Commercial GTR membranes are typically composed of synthetic polymers that have had mild clinical success mostly because of their lack of proper bioactivity and appropriate degradation profile. In this study, a natural polymer, aloe vera was blended with polycaprolactone (PCL) to create nanofibrous GTR membranes by electrospinning. Aloe vera has proven anti-inflammatory properties and enhances the regeneration of periodontium tissues. PCL, a synthetic polymer, is well known to produce miscible polyblends nanofibers with natural polymers. Nanofibrous membranes with varying composition of PCL to aloe vera were fabricated, and several physicochemical and biological properties, such as fiber morphology, wettability, chemical structure, mechanical strength, and cellular compatibility of the membranes were analyzed. PCL/aloe vera membranes with ratios from 100/00 to 70/30 showed good uniformity in fiber morphology and suitable mechanical properties, and retained the integrity of their fibrous structure in aqueous solutions. Experimental results, using cell viability assay and cell attachment observation, showed that the nanofibrous membranes support 3T3 cell viability and could be a potential candidate for GTR therapy.

  1. Evaluation of antimicrobial efficacy of Aloe vera and its effectiveness in decontaminating gutta percha cones

    Directory of Open Access Journals (Sweden)

    Prakash P Athiban

    2012-01-01

    Results: The zones of inhibition on the agar plate were measured as 24mm,21mm and 24mm respectively. The broth remained clear even after 48 hours of incubation. Conclusion: We conclude that Aloe vera is indeed effective as a GP decontaminant and it holds a promising future as a medium for storage of GP cones.

  2. Facile fabrication of aloe vera containing PCL nanofibers for barrier membrane application.

    Science.gov (United States)

    Carter, Princeton; Rahman, Shekh M; Bhattarai, Narayan

    2016-01-01

    Guided tissue regeneration (GTR) is a widely used method in dental surgical procedures that utilizes a barrier membrane to exclude migration of epithelium and ensure repopulation of periodontal ligament cells at the sites having insufficient gingiva. Commercial GTR membranes are typically composed of synthetic polymers that have had mild clinical success mostly because of their lack of proper bioactivity and appropriate degradation profile. In this study, a natural polymer, aloe vera was blended with polycaprolactone (PCL) to create nanofibrous GTR membranes by electrospinning. Aloe vera has proven anti-inflammatory properties and enhances the regeneration of periodontium tissues. PCL, a synthetic polymer, is well known to produce miscible polyblends nanofibers with natural polymers. Nanofibrous membranes with varying composition of PCL to aloe vera were fabricated, and several physicochemical and biological properties, such as fiber morphology, wettability, chemical structure, mechanical strength, and cellular compatibility of the membranes were analyzed. PCL/aloe vera membranes with ratios from 100/00 to 70/30 showed good uniformity in fiber morphology and suitable mechanical properties, and retained the integrity of their fibrous structure in aqueous solutions. Experimental results, using cell viability assay and cell attachment observation, showed that the nanofibrous membranes support 3T3 cell viability and could be a potential candidate for GTR therapy. PMID:26878323

  3. Radioprotective effects of Aloe vera leaf extract on skin of Swiss mice after gamma irradiation

    International Nuclear Information System (INIS)

    Full text: Biological effects of radiation are detrimental to life. Skin being a cell-renewal system is one of the best organ for studying radiation induced effects and their modulation by antioxidants. An attempt has been made to evaluate radioprotective efficacy of Aloe vera leaf extract on skin in Swiss mice (1g/kg body wt/day). The mice selected from inbreed colony were divided into two groups. The first group was given Aloe vera extract orally for 15th consecutive days and served as experimental group while the other group received DDW (vol. equal to Aloe extract) to serve as control group. On the 15th day, after 30 min of above treatment animals of both the groups were exposed to 2 Gy gamma irradiation and autopsied on 6h 1, 3, 7, 14 and 21 days. DNA as well as total protein decreases in control group as compared to the normal value. Surprisingly, in experimental group, DNA and protein increases in comparison to the control group. Thus, Aloe vera were found to have positive influence against radiation induced alterations on skin of Swiss albino mice

  4. Characterization of mangrove forest types based on ALOS-PALSAR in overall Indonesian archipelago

    Science.gov (United States)

    Darmawan, S.; Takeuchi, W.; Vetrita, Y.; Winarso, G.; Wikantika, K.; Sari, D. K.

    2014-06-01

    Indonesia has largest mangrove forest in the world, total area around 3.5 million ha or 17% - 23% from mangrove forest in the world. Mangrove forest provides products and services, such as carbon balance of the coastal zone. Mapping and monitoring biomass of mangrove is very important but field survey of mangrove biomass and productivity in overall Indonesia is very difficult. Global-scale mosaics with HH and HV backscatter of Advanced Land Observing Satellite (ALOS) Phased Array L-band Synthetic Aperture Radar (PALSAR) which is 50-m spatial resolution has been generated. This image available for identification and monitoring mangrove forest. The Objective of this research to investigate characterization of mangrove forest types based on ALOS-PALSAR in overall Indonesian archipelago. Methodology consists of collecting ALOS-PALSAR image for overall Indonesian archipelago, preprocessing and mosaicking, collecting region of interest of mangrove forest, plotting, ground survey, characterization and classification. The result of this research has showed characterization of mangrove forest types based on ALOS-PALSAR. Indonesian mangrove forest types has HH value around -10 dB until -7 dB and HV value around -17 dB until -13 dB. Higher of HH and HV backscatters value indicated higher of level biomass. Based on scatter plot of HH and HV, Indonesian mangrove forest can be classified in three level biomass. Generally level biomass of mangrove forest in Indonesia archipelago is moderate.

  5. ALOE EN VENEZUELA: DE LA CADENA DE VALOR AL DISTRITO INDUSTRIAL

    Directory of Open Access Journals (Sweden)

    Henri Jesús Piña Zambrano

    2010-01-01

    Full Text Available Desde la perspectiva del estudio de los conglomerados, se contrastaron las aportaciones teóricas acerca de los conglomerados y el funcionamiento y desempeño de la cadena del aloe en el Estado Falcón (Venezuela, partiendo de la hipótesis de que esta cadena ha seguido un patrón evolutivo sustentado en el legado histórico de recursos que han favorecido la siembra y explotación del aloe en el estado. Sin embargo, se considera un escaso aprovechamiento de este patrimonio como estrategia para conformar un eficiente y competitivo conglomerado agroindustrial. La investigación se sustenta en estudios realizados entre 2003 y 2007 en las zonas productoras del aloe. Se identifican en la cadena los elementos típicos de un conglomerado (proximidad geográfica, redes, innovación e institucionalidad bajo un patrón organizativo que no promueve la consolidación del conglomerado. En la cadena del aloe no termina de crearse la atmósfera industrial necesaria para iniciar la districtualización de esta actividad productiva.

  6. Disinfection of Dental Unit Water Line Using Aloe Vera: In Vitro Study

    Directory of Open Access Journals (Sweden)

    Sonia Pareek

    2013-01-01

    Full Text Available Context. Dental unit waterlines may be heavily contaminated with microorganisms and are a potential source of infection for both practicing staff and immunocompromised patients particularly. Contamination of dental unit water lines could be inhibited with the use of disinfectants. The present study investigates the effect of aloe-vera-based disinfectant in reducing the microbial growth in dental unit water lines (DUWLs. Aims. To compare the efficacy of aloe vera, hydrogen peroxide (H2O2, and 5% sodium hypochlorite (NaOCl in controlling microbial contamination of DUWLs. Materials and Methods. After obtaining baseline water samples, the dental unit waterlines were treated with aloe vera, 10% hydrogen peroxide, and 5% sodium hypochlorite. Each of the three disinfectants was used in increasing concentrations and their inhibiting effect was compared. Water samples were analyzed for microbiological quality by the total viable count (TVC method. Statistical Analysis Used. SPSS 16. Results. There was significant reduction in mean CFU/ml when treated with disinfectants each for a period of one week. Aloe-vera solution was found to be the most effective in reducing the microbial colonies. Conclusions. Improving the water quality from dental unit water lines is of considerable importance; chemical-based disinfectants can be replaced with herbal disinfectants for treating microbial contamination in dental unit waterlines.

  7. Nation-Wide Clear-Cut Mapping in Sweden Using ALOS PALSAR Strip Images

    Directory of Open Access Journals (Sweden)

    Anders Persson

    2012-06-01

    Full Text Available Advanced Land Observing Satellite (ALOS Phased Array L-band type Synthetic Aperture Radar (PALSAR backscatter images with 50 m pixel size (strip images at HV-polarization were used to map clear-cuts at a regional and national level in Sweden. For a set of 31 clear-cuts, on average 59.9% of the pixels within each clear-cut were correctly detected. When compared with a one-pixel edge-eroded version of the reference dataset, the accuracy increased to 88.9%. With respect to statistics from the Swedish Forest Agency, county-wise clear-felled areas were underestimated by the ALOS PALSAR dataset (between 25% and 60% due to the coarse resolution. When compared with statistics from the Swedish National Forest Inventory, the discrepancies were larger, partly due to the estimation errors from the plot-wise forest inventory data. In Sweden, for the time frame of 2008–2010, the total area felled was estimated to be 140,618 ha, 172,532 ha and 194,586 ha using data from ALOS PALSAR, the Swedish Forest Agency and the Swedish National Forest Inventory, respectively. ALOS PALSAR strip images at HV-polarization appear suitable for detection of clear-felled areas at a national level; nonetheless, the pixel size of 50 m is a limiting factor for accurate delineation of clear-felled areas.

  8. Physico-chemical evaluation of bitter and non-bitter Aloe and their raw juice for human consumption

    OpenAIRE

    Azam, M. M.; Kumar, S.; Pancholy, A.; Patidar, M.

    2012-01-01

    In addition to Aloe vera which is bitter in taste, a non-bitter Aloe is also found in arid part of Rajasthan. This non-bitter Aloe (NBA) is sporadically cultivated as vegetable and for health drink. In spite of its cultivation and various uses, very little information is available about its detailed botanical parameters and chemical characters. This study aims to evaluate the physico-chemical characters of NBA through employing floral morphology, leaf characters and leaf gel and to compare th...

  9. Effects of four nutrient solutions on vegetative traits of Aloe vera L. cv. Austin at six harvest periods

    OpenAIRE

    F. Salighehdar; Sh. Sedaghat-Hor; J. Olfati

    2013-01-01

    Aloe vera is a perennial liliaceous plant with succulent green leaves joined at the stem in a whorled pattern. It is highly appreciated due to its short growth period and high economic value among all the aloe species, and is used in pharmaceuticals, cosmetic products and food products. In order to improve Aloe vera cultivation in soilless culture, an experiment was conducted in 2011 in greenhouse of College of Agriculture, University of Guilan, Rasht, Iran, as a split plot bi-factorial in co...

  10. IDENTIFICATION OF PHYTO-COMPONENTS AND ITS BIOLOGICAL ACTIVITIES OF ALOE VERA THROUGH THE GAS CHROMATOGRAPHY-MASS SPECTROMETRY

    OpenAIRE

    P T.V Lakshmi; Pa Rajalakshmi

    2011-01-01

    In this study, the bioactive components of Aloe vera leaves have been evaluated using GC/MS. The chemical compositions of the n-hexane extract of Aloe vera were investigated using Perkin-Elmer Gas Chromatography–Mass Spectrometry, while the mass spectra of the compounds found in the extract was matched with the National Institute of Standards and Technology (NIST) library. GC/MS analysis of n-hexane extract of Aloe vera revealed the existence of twenty six bioactive compounds. The results of ...

  11. The Innocent in the Strange World-The Application of Reader Theory in the Interpretation of Daisy Miller

    Institute of Scientific and Technical Information of China (English)

    LIU Li-hua

    2014-01-01

    Henry James’s first novella Daisy Miller brought him popularity and literary reputation after its publication. Through the application of reader theory and a close reading of the text, this article analyzes Daisy’s strong personality and her misfortunes during her trip to Europe, and reveals how the novella highlights the conflict between American frankness and innocence and Eu-ropean sophistication. Besides, this article also elaborates on James’unique artistic skills-central consciousness and psychological analysis through his choice of narrative point of view, which contribute to the theme and the artistic charm of Daisy Miller.

  12. ″Moving inward as well as north″: The Historical Imagination in Arthur Miller's The Crucible and Timebends

    Institute of Scientific and Technical Information of China (English)

    Douglas Tallack

    2005-01-01

    Arthur Miller, one of the most admirable of Americans to come out of the ″American century″, died in 2005, aged 89. In the UK, at least, his work has undergone a revival and the themes of his great plays remain resonant, even though, in many respects, they are historically specific. The relationship between literature and history - whether conceived as a symbolist or allegorical relationship - together with an instance of the past invading the present, are brought out in a compelling episode in Miller's autobiography, Timebends, and offer a way of talking about those inter-connections in The Crucible.

  13. Synonymy of Plotococcus Miller & Denno with Leptococcus Reyne, and description of a new species from Colombia (Hemiptera: Pseudococcidae).

    Science.gov (United States)

    Kondo, Takumasa; Gullan, Penny J

    2008-01-01

    Plotococcus Miller & Denno is synonymized with Leptococcus Reyne (Coccoidea: Pseudococcidae). The genus is redescribed and the adult female of the type species, L. metroxyli Reyne, is redescribed and illustrated. All species hitherto included in Plotococcus are transferred to Leptococcus as L. capixaba (Kondo) comb. nov., L. eugeniae (Miller & Denno) comb. nov., L. hambletoni (Kondo) comb. nov., L. minutus (Hempel) comb. nov., and L. neotropicus (Williams & Granara de Willink) comb. nov. A new species of Leptococcus, L. rodmani Kondo sp. n., from leaves of Guarea guidonia (Meliaceae) from Colombia, is described and illustrated based on the adult female. A revised key to adult females of all species in the genus is provided.

  14. Treatment of Multiple Adjacent Miller Class III Gingival Recessions with a Modified Tunnel Technique: A Case Series.

    Science.gov (United States)

    Yaman, Duygu; Demirel, Korkud; Aksu, Seden; Basegmez, Cansu

    2015-01-01

    Modified coronally advanced tunnel (MCAT) technique with connective tissue graft (CTG) was used in treating multiple adjacent Miller Class III gingival recessions in nine patients. Clinical evaluations were recorded at baseline and 12 months after surgery. The results showed that 50% of complete root coverage and 78% of mean root coverage were attained 1 year after surgery and interdental space fill was 73% at 12 months. The study demonstrated that CTG using the MCAT technique may be an efficient way to treat multiple adjacent Miller Class III gingival recessions, especially when aiming for interdental space fill. Success, however, seems to be related to the amount of tissue present initially.

  15. ANTIMICROBIAL AND PHYTOCHEMICAL ANALYSIS OF ALOE VERA L

    Directory of Open Access Journals (Sweden)

    Mariappan V

    2012-10-01

    Full Text Available The present study was made to attempt the antimicrobial and phytochemical analysis of Aloe vera L (babosa. The antimicrobial activity method was using Muller and Hinton agar Dimethyl sulfoxide (DMSO was used. The Overnight incubated bacterial culture, Staphylococcus aureus, Bacillus subtillis, Proteus vulgaris, Pseudomonas aeroginosa, Enterobacter aerogenes, Klebshiella sp, Salmonella sp, Shigella sonie, S. spidermiods. In phytochemical studies, the leaf extract were analysed for the flavonoids, pholabatannis, glycosides, phenols, catachol, resins, saponins, lipids and fats, tannis, acidic compounds, terpenoids, reducing sugars, anthraquinone, carbohydrates, steroids, and sterols etc. In analysis of Tannin compounds brownish green colour developed to indicate the presence of Tannin. In this screening process Tannin, Saponin, Flavonoids and Terpenoids compounds revealed positive resultsAntibacterial activity of A.vera was analysed against E.coli, Enterobacter aerogens, Staphylococcus sp, Proteus mirabilus, Pseudomonas sp., Shigella sonie, Salmonella sp, S. spidermiods, Klebshiella sp. Among the three bacterial organisms maximum growth suppression was observed in Staphylococcus sp, Enterobacter aerogens and Klebsiella sp. Anti bacterial activity of A.vera was analysed against Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa and E. coli. A.vera leaf gel can inhibit the growth of two gram positive bacteria Shigella flexneri and Streptococcus pyogenes. Specific plant compounds such as anthroquinones and dihydroxy anthroquinones as well as Saponins have been proposed to have direct antimicrobial activity.The antioxidant activity of A.vera leaf and gel extract by using DPPH free radical scavenging assay method. The antioxyactivity of A.vera leaf and gel aqueous extract was determined at the concentration (100, 200, 300, 400 and 500 µg/ml and IC 50 was calculated. In, DNA protective activity of A.vera on blood DNA against free

  16. The increasing of fibroblast growth factor 2, osteocalcin, and osteoblast due to the induction of the combination of Aloe vera and 2% xenograft concelous bovine

    Directory of Open Access Journals (Sweden)

    Utari Kresnoadi

    2012-12-01

    Full Text Available Background: To make a successfull denture prominent ridge is needed, preservation on tooth extraction socket is needed in order to prevent alveol bone resorption caused by revocation trauma. An innovative modification of the material empirically suspected to be able reduce inflammation caused by the revocation trauma is a combination of Aloe vera and xenograft concelous bovine (XCB and Aloe vera is a biogenic stimulator and accelerating the growth of alveolar ridge bone after tooth extraction. Purpose: The research was aimed to determine of the increasing alveol bone formation by inducing the combination of Aloe vera and 2% xenograft concelous bovine. Methods: To address the problems, the combination of Aloe vera and xenograft concelous bovine was induced into the tooth extraction sockets of Cavia cabayas which devided on 8 groups. Groups control, filled with XCB, Aloe vera and Aloe vera and XCB combination, at 7 days and 30 days after extraction. Afterwards, immunohistochemical examination was conducted to examine the expressions of FGF-2 and osteocalcin, as the product of the growth of osteoblasts. Results: There were significantly increases expression of FGF-2 and osteocalcyn on group which filled with XCB, Aloe vera and combined Aloe vera and XCB. Conclusion: It may be concluded that the induction of the combination of Aloe vera and xenograft concelous bovine into the tooth sockets can enhance the growth expressions of FGF-2 and osteocalcin as the product of osteoblasts, thus, the growth of alveolar bone was increased.Latar belakang: Untuk keberhasilan pembuatan gigitiruan diperlukan ridge yang prominent, maka diperlukan suatu preservasi soket pencabutan gigi untuk mencegah terjadinya resopsi tulang alveolar akibat trauma pencabutan. Suatu inovasi modifikasi bahan yang diduga secara empiris dapat mengurangi keradangan karena trauma pencabutan adalah berupa kombinasi Aloe vera dan xenograft concelous bovine (XCB. Aloe vera yang merupakan

  17. Clinical Effectiveness of Aloe Vera in the Management of Oral Mucosal Diseases- A Systematic Review

    Science.gov (United States)

    Nair, Gopakumar Ramachandran; Naidu, Giridhar Seetharam; Jain, Supreet; Makkad, Ramanpal Singh; Jha, Abhishek

    2016-01-01

    Introduction Aloe vera is well known for its medicinal properties which lead to its application in treating various diseases. Its use in treating oral lesions has not been much documented in literature. Aim Although, systematic reviews on aloe vera and its extracts have been done earlier, but in relation to oral diseases this is the first systematic review. The aim of the present systematic review was to compile evidence based studies on the effectiveness of Aloe vera in treatment of various oral diseases. Materials and Methods Computerized literature searches were performed to identify all published articles in the subject. The following databases were used: PUBMED [MEDLINE], SCOPUS, COCHRANE DATABASE, EMBASE and SCIENCE DIRECT using specific keywords. The search was limited to articles published in English or with an English Abstract. All articles (or abstracts if available as abstracts) were read in full. Data were extracted in a predefined fashion. Assessment was done using Jadad score. Results Fifteen studies satisfied the inclusion criteria. Population of sample study ranged from 20 patients to 110 patients with clinically diagnosed oral mucosal lesions. Out of 15 studies, five were on patients with oral lichen planus, two on patients with oral submucous fibrosis, other studies were carried on patients with burning mouth syndrome, radiation induced mucositis, candida associated denture stomatitis, xerostomic patients and four were on minor recurrent apthous stomatitis. Most studies showed statistically significant result demonstrating the effectiveness of Aloe vera in treatment of oral diseases. Conclusion Although there are promising results but in future, more controlled clinical trials are required to prove the effectiveness of Aloe vera for management of oral diseases. PMID:27656587

  18. Case Reports of Bedsores Using Aloe Vera Gel Powder with High Molecular Weight

    Directory of Open Access Journals (Sweden)

    Keizo Matsuo

    2009-01-01

    Full Text Available It has been reported that the Japanese have higher rate of life expectancy and that Japan is rapidly becoming a super aging society. Almost 5 per cent of the aged, who develop diseases such as cerebrovascular related disorders, mental problems, fractures, cancer and infections also end up suffering from bedsores. It has been found that patients often opt for treatment, when the bedsores become very severe and adding more complications in their treatment. It may be presumed that prevention and early detection are vital for the treatment of bed sores. In our present study, we have tested herbal formulations having Aloe vera gel powder for its efficacy and activity on bed sores. Aloe vera gel powder with high molecular weight (AHM was prepared from the gel part, by washing with running water using the patented freeze-drying under micro wave and far infra red irradiations in which barbaloin content was less than 10 ppm in powder form. The treatment was given by applying the macromolecule aloe ointment for bedsores from I degree to Il degree ulcer patients. The results have shown that AHM in the ointment form indicated a high possibility to cure bedsores. Being very difficult to cure, due to the patient′s peculiar conditions such as old age, inability of the patient to turn by himself/herself and also due to complications caused by other symptoms. We were able to confirm the effectiveness of the macromolecule aloe ointment in four cases of bedsores with two cases of positive control, using the Design Score and by checking the side effects. In this study, our report is based on the preclinical trials for bedsores by the external use of the macromolecule aloe ointment.

  19. Diffusion of hydroxyl ions from calcium hydroxide and Aloe vera pastes.

    Science.gov (United States)

    Batista, Victor Eduardo de Souza; Olian, Douglas Dáquila; Mori, Graziela Garrido

    2014-01-01

    This study evaluated the diffusion through the dentinal tubules of hydroxyl ions from different calcium hydroxide (CH) pastes containing Aloe vera. Sixty single-rooted bovine teeth were used. The tooth crowns were removed, the root canals were instrumented and the specimens were assigned to 4 groups (n=15) according to the intracanal medication: Group CH/S - CH powder and saline paste; Group CH/P - CH powder and propylene glycol paste; Group CH/A - calcium hydroxide powder and Aloe vera gel paste; Group CH/A/P - CH powder, Aloe vera powder and propylene glycol paste. After placement of the root canal dressings, the teeth were sealed coronally and apically with a two-step epoxy adhesive. The teeth were placed in identified flasks containing deionized water and stored in an oven with 100% humidity at 37 °C. After 3 h, 24 h, 72 h, 7 days, 15 days and 30 days, the deionized water in the flasks was collected and its pH was measured by a pH meter. The obtained data were subjected to statistical analysis at a significance level of 5%. The results demonstrated that all pastes provided diffusion of hydroxyl ions through the dentinal tubules. The combination of Aloe vera and CH (group CH/A) provided a constant release of calcium ions. Group CH/A/P showed the highest pH at 24 and 72 h. In conclusion, the experimental pastes containing Aloe vera were able to enable the diffusion of hydroxyl ions through the dentinal tubules.

  20. In-vitro assessment and pharmacodynamics of nimesulide incorporated Aloe vera transemulgel.

    Science.gov (United States)

    Vandana, K R; Yalavarthi, Prasanna R; Sundaresan, C R; Sriramaneni, Raghava N; Vadlamudi, Harini C

    2014-06-01

    The aim of the investigation was to prepare nimesulide emulsion for incorporation in Aloe vera gel base to formulate 'nimesulide - Aloe vera transemulgel' (NAE) and to carryout in-vitro assessment and in-vivo anti-inflammatory studies of the product. Although the use of nimesulide is banned for oral administration, due to its potential for inducing hepatotoxicity and thrombocytopenia, the use of nimesulide for topical delivery is prominent in the treatment of many inflammatory conditions including rheumatoid arthritis. The drug loading capacity of transdermal gels is low for hydrophobic drugs such as nimesulide. Nimesulide can be effectively incorporated into emulgels (a combination of emulsion and gel). Aloe vera has a mild anti-inflammatory effect and in the present study Aloe vera gel was formulated and used as a gel base to prepare NAE. The emulgels thus prepared were evaluated for viscosity, pH, in-vitro permeation, stability and skin irritation test. In-vivo anti-inflammatory studies were performed using carrageenan induced hind paw edema method in Wistar rats. The results were compared with that of commercial nimesulide gel (CNG). From the in-vitro studies, effective permeation of nimesulide from NAE (53.04 %) was observed compared to CNG (44.72 %) at 30 min indicating better drug release from NAE. Topical application of the emulgel found no skin irritation. Stability studies proved the integrity of the formulation. The percentage of inhibition of edema was highest for the prepared NAE (67.4 % inhibition after 240 min) compared to CNG (59.6 %). From our results, it was concluded that the Aloe vera gel acts as an effective gel base to prepare nimesulide emulgel with high drug loading capacity (86.4 % drug content) compared to CNG (70.5 % drug content) with significant anti-inflammatory effect.