WorldWideScience

Sample records for alloy-ehi 868

  1. 7 CFR 868.309 - Information.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Information. 868.309 Section 868.309 Agriculture... Application of Standards § 868.309 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for approved devices,...

  2. 7 CFR 868.209 - Information.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Information. 868.209 Section 868.209 Agriculture... Application of Standards § 868.209 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for approved devices,...

  3. 7 CFR 868.260 - Information.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Information. 868.260 Section 868.260 Agriculture... Governing Application of Standards § 868.260 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for...

  4. 21 CFR 868.5580 - Oxygen mask.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Oxygen mask. 868.5580 Section 868.5580 Food and... ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5580 Oxygen mask. (a) Identification. An oxygen mask is a device placed over a patient's nose, mouth, or tracheostomy to administer oxygen or aerosols. (b)...

  5. 21 CFR 868.5180 - Rocking bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Rocking bed. 868.5180 Section 868.5180 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5180 Rocking bed. (a) Identification. A rocking bed is a...

  6. 21 CFR 868.1030 - Manual algesimeter.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Manual algesimeter. 868.1030 Section 868.1030 Food... DEVICES ANESTHESIOLOGY DEVICES Diagnostic Devices § 868.1030 Manual algesimeter. (a) Identification. A manual algesimeter is a mechanical device intended to determine a patient's sensitivity to pain...

  7. 21 CFR 172.868 - Ethyl cellulose.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Ethyl cellulose. 172.868 Section 172.868 Food and... Multipurpose Additives § 172.868 Ethyl cellulose. The food additive ethyl cellulose may be safely used in food in accordance with the following prescribed conditions: (a) The food additive is a cellulose...

  8. 21 CFR 868.5470 - Hyperbaric chamber.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hyperbaric chamber. 868.5470 Section 868.5470 Food... DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5470 Hyperbaric chamber. (a) Identification. A hyperbaric chamber is a device that is intended to increase the environmental oxygen pressure to promote...

  9. 21 CFR 868.2377 - Apnea monitor.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Apnea monitor. 868.2377 Section 868.2377 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES... rate and other physiological parameters linked to the presence or absence of adequate respiration....

  10. 21 CFR 868.2700 - Pressure regulator.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Pressure regulator. 868.2700 Section 868.2700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... purposes and that is used to convert a medical gas pressure from a high variable pressure to a lower,...

  11. 21 CFR 868.5300 - Carbon dioxide absorbent.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Carbon dioxide absorbent. 868.5300 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5300 Carbon dioxide absorbent. (a) Identification. A carbon dioxide absorbent is a device intended for medical purposes that consists of...

  12. 21 CFR 868.1400 - Carbon dioxide gas analyzer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Carbon dioxide gas analyzer. 868.1400 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Diagnostic Devices § 868.1400 Carbon dioxide gas analyzer. (a) Identification. A carbon dioxide gas analyzer is a device intended to measure the concentration of carbon...

  13. 21 CFR 868.5310 - Carbon dioxide absorber.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Carbon dioxide absorber. 868.5310 Section 868.5310...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5310 Carbon dioxide absorber. (a) Identification. A carbon dioxide absorber is a device that is intended for medical purposes and that is used in...

  14. 7 CFR 868.301 - Definition of milled rice.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Definition of milled rice. 868.301 Section 868.301... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Milled Rice Terms Defined § 868.301 Definition of milled rice. Whole or broken kernels of rice (Oryza sativa L.) from which the hulls and...

  15. 7 CFR 868.201 - Definition of rough rice.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Definition of rough rice. 868.201 Section 868.201... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Rough Rice Terms Defined § 868.201 Definition of rough rice. Rice (Oryza sativa L.) which consists of 50 percent or more of paddy kernels...

  16. 21 CFR 868.1730 - Oxygen uptake computer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Oxygen uptake computer. 868.1730 Section 868.1730...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Diagnostic Devices § 868.1730 Oxygen uptake computer. (a) Identification. An oxygen uptake computer is a device intended to compute the amount of oxygen consumed by...

  17. 21 CFR 868.1670 - Neon gas analyzer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Neon gas analyzer. 868.1670 Section 868.1670 Food... DEVICES ANESTHESIOLOGY DEVICES Diagnostic Devices § 868.1670 Neon gas analyzer. (a) Identification. A neon gas analyzer is a device intended to measure the concentration of neon in a gas mixture exhaled by...

  18. 21 CFR 868.5915 - Manual emergency ventilator.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Manual emergency ventilator. 868.5915 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5915 Manual emergency ventilator. (a) Identification. A manual emergency ventilator is a device, usually incorporating a bag and valve, intended...

  19. 21 CFR 868.2450 - Lung water monitor.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Lung water monitor. 868.2450 Section 868.2450 Food... DEVICES ANESTHESIOLOGY DEVICES Monitoring Devices § 868.2450 Lung water monitor. (a) Identification. A lung water monitor is a device used to monitor the trend of fluid volume changes in a patient's lung...

  20. 21 CFR 868.5995 - Tee drain (water trap).

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Tee drain (water trap). 868.5995 Section 868.5995...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5995 Tee drain (water trap). (a) Identification. A tee drain (water trap) is a device intended to trap and drain water that collects in...

  1. 21 CFR 868.2380 - Nitric oxide analyzer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nitric oxide analyzer. 868.2380 Section 868.2380...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Monitoring Devices § 868.2380 Nitric oxide analyzer. (a) Identification. The nitric oxide analyzer is a device intended to measure the concentration of nitric oxide...

  2. 21 CFR 868.5700 - Nonpowered oxygen tent.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nonpowered oxygen tent. 868.5700 Section 868.5700...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5700 Nonpowered oxygen tent. (a) Identification. A nonpowered oxygen tent is a device that encloses a patient's head and upper body to...

  3. 21 CFR 868.5330 - Breathing gas mixer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Breathing gas mixer. 868.5330 Section 868.5330...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5330 Breathing gas mixer. (a) Identification. A breathing gas mixer is a device intended for use in conjunction with a respiratory...

  4. 21 CFR 868.5240 - Anesthesia breathing circuit.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Anesthesia breathing circuit. 868.5240 Section 868...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5240 Anesthesia breathing circuit. (a) Identification. An anesthesia breathing circuit is a device that is intended to administer medical gases to...

  5. 21 CFR 868.1 - Scope.

    Science.gov (United States)

    2010-04-01

    ... DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES General Provisions § 868.1 Scope. (a) This part sets forth the classification of anesthesiology... equivalent to other devices, as required by § 807.87. (c) To avoid duplicative listings, an...

  6. 7 CFR 868.36 - Loss of identity.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Loss of identity. 868.36 Section 868.36 Agriculture... identity. (a) Lots. The identity of a packaged lot, bulk lot, or sublot of a commodity shall be considered... or location after the time of original inspection, unless the identity is preserved; or (2)...

  7. 21 CFR 868.5955 - Intermittent mandatory ventilation attachment.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Intermittent mandatory ventilation attachment. 868.5955 Section 868.5955 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... mandatory ventilation attachment. (a) Identification. An intermittent mandatory ventilation (IMV)...

  8. 21 CFR 868.6175 - Cardiopulmonary emergency cart.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Cardiopulmonary emergency cart. 868.6175 Section... (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Miscellaneous § 868.6175 Cardiopulmonary emergency cart. (a) Identification. A cardiopulmonary emergency cart is a device intended to store and...

  9. 21 CFR 868.2775 - Electrical peripheral nerve stimulator.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Electrical peripheral nerve stimulator. 868.2775... (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Monitoring Devices § 868.2775 Electrical peripheral nerve stimulator. (a) Identification. An electrical peripheral nerve stimulator (neuromuscular blockade monitor)...

  10. 21 CFR 868.5165 - Nitric oxide administration apparatus.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nitric oxide administration apparatus. 868.5165... (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5165 Nitric oxide administration apparatus. (a) Identification. The nitric oxide administration apparatus is a device used to add...

  11. 7 CFR 868.83 - Automatic suspension of license by change in employment.

    Science.gov (United States)

    2010-01-01

    ... Inspectors, Technicians, and Samplers § 868.83 Automatic suspension of license by change in employment. A... request of the licensee, the license will be reinstated subject to the provisions of § 868.81(a) and (b)....

  12. 21 CFR 868.5365 - Posture chair for cardiac or pulmonary treatment.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Posture chair for cardiac or pulmonary treatment. 868.5365 Section 868.5365 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5365 Posture...

  13. 21 CFR 868.5710 - Electrically powered oxygen tent.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Electrically powered oxygen tent. 868.5710 Section... tent. (a) Identification. An electrically powered oxygen tent is a device that encloses a patient's... temperature and humidity of the breathing gases. This generic type device includes the pediatric aerosol...

  14. 21 CFR 868.5610 - Membrane lung for long-term pulmonary support.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Membrane lung for long-term pulmonary support. 868... SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5610 Membrane lung for long-term pulmonary support. (a) Identification. A membrane lung for long-term pulmonary...

  15. 7 CFR 868.82 - Voluntary cancellation or suspension of license.

    Science.gov (United States)

    2010-01-01

    ... Inspectors, Technicians, and Samplers § 868.82 Voluntary cancellation or suspension of license. Upon request... request by the licensee within 1 year, subject to the provisions of § 868.81(a) and (b); a license that has been cancelled shall be considered void and shall not be subject to return or renewal....

  16. 21 CFR 868.5965 - Positive end expiratory pressure breathing attachment.

    Science.gov (United States)

    2010-04-01

    ... attachment. 868.5965 Section 868.5965 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... Positive end expiratory pressure breathing attachment. (a) Identification. A positive end expiratory pressure (PEEP) breathing attachment is a device attached to a ventilator that is used to elevate...

  17. 21 CFR 868.1860 - Peak-flow meter for spirometry.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Peak-flow meter for spirometry. 868.1860 Section 868.1860 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... spirometry. (a) Identification. A peak-flow meter for spirometry is a device used to measure a...

  18. 7 CFR 868.10 - Information about the Service, Act, and regulations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Information about the Service, Act, and regulations... § 868.10 Information about the Service, Act, and regulations. Information about the Service, Act... INSPECTION, PACKERS AND STOCKYARD ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT...

  19. IEEE 802.15.4 transceiver for the 868/915 MHz band using Software Defined Radio

    OpenAIRE

    Zitouni, Rafik; Ataman, Stefan; Mathian, Marie; George, Laurent

    2013-01-01

    This paper reports an implementation of the PHY specifications of the IEEE 802.15.4 standard for the frequency band 868 915 MHz on a Software Defined Radio (SDR) platform. This standard is defined for low power, low data rate and low cost wireless networks. These specifications are used by the Zigbee technology for various applications such as home automation, industry monitoring or medical surveillance. Several hardware PHY 868/915 MHz band IEEE 802.15.4 transceiver implementations have been...

  20. 双核芯双无损 昂达VX868

    Institute of Scientific and Technical Information of China (English)

    柠檬草; 黄新乐

    2007-01-01

    VX868是昂达HONEY系列的最新精品,外观上延续了HONEY系列一触即蓝的时尚风格精致的亚克力面板和铝合金底壳,材质高档,26万色2.8英寸QVGA高清TFT彩屏同时还支持FLV视频和FLAC、APE双无损格式。

  1. Interference Measurements in the European 868 MHz ISM Band with Focus on LoRa and SigFox

    DEFF Research Database (Denmark)

    Lauridsen, Mads; Vejlgaard, Benny; Kovács, István

    2017-01-01

    . The focus is on the Low Power Wide Area technologies LoRa and SigFox. The measurements show that there is a 22-33 % probability of interfering signals above -105 dBm within the mandatory LoRa and SigFox 868.0-868.6 MHz band in a shopping area and a business park in downtown Aalborg, which thus limits...... the potential coverage and capacity of LoRa and SigFox. However, the probability of interference is less than 3 % in the three other measurement locations in Aalborg. Finally, a hospital and an industrial area are shown to experience high activity in the RFID subband 865-868 MHz, while the wireless audio band...

  2. Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis.

    Directory of Open Access Journals (Sweden)

    John K Thuita

    Full Text Available There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness. A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs of HAT. The development of oral medications is a key objective of the Consortium for Parasitic Drug Development (CPDD. In this study, we investigated the safety, pharmacokinetics, and efficacy of a new orally administered CPDD diamidine prodrug, 2,5-bis[5-(N-methoxyamidino-2-pyridyl]furan (DB868; CPD-007-10, in the vervet monkey model of first stage HAT. DB868 was well tolerated at a dose up to 30 mg/kg/day for 10 days, a cumulative dose of 300 mg/kg. Mean plasma levels of biomarkers indicative of liver injury (alanine aminotransferase, aspartate aminotransferase were not significantly altered by drug administration. In addition, no kidney-mediated alterations in creatinine and urea concentrations were detected. Pharmacokinetic analysis of plasma confirmed that DB868 was orally available and was converted to the active compound DB829 in both uninfected and infected monkeys. Treatment of infected monkeys with DB868 began 7 days post-infection. In the infected monkeys, DB829 attained a median C(max (dosing regimen that was 12-fold (3 mg/kg/day for 7 days, 15-fold (10 mg/kg/day for 7 days, and 31-fold (20 mg/kg/day for 5 days greater than the IC50 (14 nmol/L against T. b. rhodesiense STIB900. DB868 cured all infected monkeys, even at the lowest dose tested. In conclusion, oral DB868 cured monkeys with first stage HAT at a cumulative dose 14-fold lower than the maximum tolerated dose and should be considered a lead preclinical candidate in efforts to develop a safe, short course (5-7 days, oral regimen for first stage HAT.

  3. 7 CFR 868.310 - Grades and grade requirements for the classes Long Grain Milled Rice, Medium Grain Milled Rice...

    Science.gov (United States)

    2010-01-01

    ... Grain Milled Rice, Medium Grain Milled Rice, Short Grain Milled Rice, and Mixed Milled Rice. (See also Â... Milled Rice Principles Governing Application of Standards § 868.310 Grades and grade requirements for the classes Long Grain Milled Rice, Medium Grain Milled Rice, Short Grain Milled Rice, and Mixed Milled...

  4. The first four-color photometric investigation of the W UMa type contact binary V868 Mon

    CERN Document Server

    Xiao, Zhou; Jiajia, He; Jia, Zhang; Linqiao, Jiang

    2016-01-01

    The first four-color light curves of V868 Mon in the $B$ $V$ $R_c$ and $I_c$ bands are presented and analyzed by using the Wilson-Devinney method of the 2013 version. It is discovered that V868 Mon is an A-subtype contact binary (f=$58.9\\,\\%$) with a large temperature difference of 916$K$ between the two components. Using the eight new times of light minimum determined by the authors together with those collected from literatures, the authors found that the general trend of the observed-calculate ($O$-$C$) curve shows a upward parabolic variation that corresponds to a long-term increase in the orbital period at a rate of $dP/dt=9.38\\times{10^{-7}}day\\cdot year^{-1}$. The continuous increase may be caused by a mass transfer from the less massive component to the more massive one.

  5. Measurements, modeling and simulation of the off-body radio channel for the implementation of bodyworn antenna diversity at 868 mhz

    NARCIS (Netherlands)

    Cotton, Simon L.; Scanlon, William G.

    2009-01-01

    This paper presents a systematic measurement campaign of diversity reception techniques for use in multiple antenna wearable systems operating at 868 MHz. The experiments were performed using six time-synchronized bodyworn receivers and considered mobile off-body communications in an anechoic chambe

  6. 基于Conrad-433/868的FIRA足球机器人无线通信系统%A wireless communication system for FIRA soccer robot based on Conrad-433/868 module

    Institute of Scientific and Technical Information of China (English)

    程福; 马英庆

    2010-01-01

    为了满足机器人足球比赛对无线通信系统快速性和准确性的要求,以德国Conrad-433/868无线收发模块为核心,构建足球机器人无线通信硬件系统的发射/接收电路.该系统具有体积小、集成度高、无调整元件、通信速率高、抑制杂波干扰能力强、易于构建、成本低廉的优点,其性能已被实验和比赛验证.

  7. A 434/868 MHz CMOS low-IF receiver with I/Q imbalance calibration for SRDs application

    Institute of Scientific and Technical Information of China (English)

    Li Juan; Zhao Feng; Ye Guojing; Hong Zhiliang

    2009-01-01

    A receiver for SRDs implemented by the 0.35μm CMOS process is presented. The receiver, together with the ADC, power amplifier (PA), frequency synthesizer and digital baseband has been integrated into a single chip solution. Low cost and low power requirements are met by optimizing the receiver architecture and circuit topology. A simple mixed-signal mode I/Q imbalance calibration circuit is proposed to enhance the IRR (image rejection ratio) so as to raise the BER. From a single 3 V power supply, the receiver consumes 5.9 mA. The measurement result shows that the receiver achieves reference sensitivity of--60 dBm and a control gain of 60 dB. The S reaches-20 dB at 433 MHz and-10 dB at 868 MHz without off-chip impedance match network. The die area is only 2 mm2 including the bias circuit.

  8. Environmental Assessment for Demolition of Lighter Than Air (LTA) Buildings 868, 869, 948 and 949 at Langley Air Force Base, Virginia

    Science.gov (United States)

    2005-04-01

    to the intersection with Nealy Avenue/ Hammond Avenue. EA for Demolition of Lighter Than Air (LTA) Buildings 868, 869, 948, 949 3.0 Affected...southeastern portion of the base. The large wind tunnels and aeronautical test equipment that comprise the NASA facility resemble a large industrial area...the Langley AFB area, groundwater occurs in a shallow water table aquifer , an upper artesian aquifer system, and the principal artesian aquifer system

  9. Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys.

    Science.gov (United States)

    Thuita, John K; Wolf, Kristina K; Murilla, Grace A; Bridges, Arlene S; Boykin, David W; Mutuku, James N; Liu, Qiang; Jones, Susan K; Gem, Charles O; Ching, Shelley; Tidwell, Richard R; Wang, Michael Z; Paine, Mary F; Brun, Reto

    2015-02-01

    Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on limited availability of drugs that are safe and efficacious, particularly against the second stage (central nervous system [CNS]) of infection. In response to this largely unmet need for new treatments, the Consortium for Parasitic Drug Development developed novel parenteral diamidines and corresponding oral prodrugs that have shown cure of a murine model of second stage HAT. As a rationale for selection of one of these compounds for further development, the pharmacokinetics and efficacy of intramuscular (IM) active diamidine 2,5-bis(5-amidino-2-pyridyl)furan (DB829; CPD-0802) and oral prodrug2,5-bis[5-(N-methoxyamidino)-2-pyridyl]furan (DB868) were compared in the vervet monkey model of second stage HAT. Treatment was initiated 28 days post-infection of monkeys with T. b. rhodesiense KETRI 2537. Results showed that IM DB829 at 5 mg/kg/day for 5 consecutive days, 5 mg/kg/day every other day for 5 doses, or 2.5 mg/kg/day for 5 consecutive days cured all monkeys (5/5). Oral DB868 was less successful, with no cures (0/2) at 3 mg/kg/day for 10 days and cure rates of 1/4 at 10 mg/kg/day for 10 days and 20 mg/kg/day for 10 days; in total, only 2/10 monkeys were cured with DB868 dose regimens. The geometric mean plasma Cmax of IM DB829 at 5 mg/kg following the last of 5 doses was 25-fold greater than that after 10 daily oral doses of DB868 at 20 mg/kg. These data suggest that the active diamidine DB829, administered IM, should be considered for further development as a potential new treatment for second stage HAT.

  10. Lyman-alpha Emission from a Luminous z=8.68 Galaxy: Implications for Galaxies as Tracers of Cosmic Reionization

    CERN Document Server

    Zitrin, Adi; Belli, Sirio; Bouwens, Rychard; Ellis, Richard S; Roberts-Borsani, Guido; Stark, Daniel P; Oesch, Pascal A; Smit, Renske

    2015-01-01

    We report the discovery of Lyman-alpha emission (Ly$\\alpha$) in the bright galaxy EGSY-2008532660 (hereafter EGSY8p7) using the MOSFIRE spectrograph at the Keck Observatory. First reported by Roberts-Borsani et al. (2015), it was selected for spectroscopic observations because of its photometric redshift ($z_{phot}=8.57^{+0.22}_{-0.43}$), apparent brightness (H$_{160}=25.26\\pm0.09$) and red Spitzer/IRAC [3.6]-[4.5] color indicative of contamination by strong oxygen emission in the [4.5] band. With a total integration of $\\sim4.3$ hours, our data reveal an emission line at $\\simeq11776$ {\\AA} which we argue is likely Ly$\\alpha$ at a redshift $z_{spec}=8.68$, in good agreement with the photometric estimate. The line was detected independently on two nights using different slit orientations and its detection significance is $\\sim7.5\\sigma$. An overlapping sky line contributes significantly to the uncertainty on the total line flux but not the overall significance. By direct addition and a Gaussian fit, we estima...

  11. Réflexions sur un critère de classification des animaux chez le savant al-Djâhiz (776-868 ) : le mode de reproduction chez les reptiles et les oiseaux

    DEFF Research Database (Denmark)

    Ben Saad, Meyssa; Provencal, Philippe; Katouzian-Safadi, Mehrnaz

    2013-01-01

    Al-Djâhiz (776-868) var en arabisk sproget naturhistoriker og litterat, som levede i Iraq i det 9. århundrede. Han skrev et zoologisk værk, som er baseret på Aristoteles' zoologi men i hvilket han også indføjer sine egne observationer og overvejelser. I denne artikel bliver hans overvejelser over...

  12. Indoor radio channel modeling and mitigation of fading effects using linear and circular polarized antennas in combination for smart home system at 868 MHz

    Science.gov (United States)

    Wunderlich, S.; Welpot, M.; Gaspard, I.

    2014-11-01

    The markets for smart home products and services are expected to grow over the next years, driven by the increasing demands of homeowners considering energy monitoring, management, environmental controls and security. Many of these new systems will be installed in existing homes and offices and therefore using radio based systems for cost reduction. A drawback of radio based systems in indoor environments are fading effects which lead to a high variance of the received signal strength and thereby to a difficult predictability of the encountered path loss of the various communication links. For that reason it is necessary to derive a statistical path loss model which can be used to plan a reliable and cost effective radio network. This paper presents the results of a measurement campaign, which was performed in six buildings to deduce realistic radio channel models for a high variety of indoor radio propagation scenarios in the short range devices (SRD) band at 868 MHz. Furthermore, a potential concept to reduce the variance of the received signal strength using a circular polarized (CP) patch antenna in combination with a linear polarized antenna in an one-to-one communication link is presented.

  13. Corrigendum to “Crystal structure solution of KMg(ND)(ND2): An ordered mixed amide/imide compound” [Int J Hydrogen Energy 39 (2) 2014) 868 - 876

    OpenAIRE

    NAPOLITANO EMILIO; DOLCI Francesco; CAMPESI RENATO; Pistidda, Claudio; Hoelzel, Markus; Moretto, Pietro; Enzo, Stefano

    2014-01-01

    This corrigendum to orignal article [Int J Hydrogen Energy 39 (2) 2014) 868 - 876] wants to points out that there are two different way to describe the structure of KMg(ND)(ND2). This was described as an orthorhombic system with space group P212121 (n.19) in the original article. However, after the publication of the article the authors found out that the structure can also be described in higher symmetry using the space group Pnma (n.62) in the orthorhombic system. The corrigendum describes...

  14. 7 CFR 868.73 - Corrected certificates.

    Science.gov (United States)

    2010-01-01

    ... authorized agent who affixed the name or signature, or both. Errors found during this process shall be... this section and the instructions, corrected certificates shall show— (i) The terms “Corrected Original... that has been superseded by another certificate or on the basis of a subsequent analysis for quality....

  15. 7 CFR 868.1 - Meaning of terms.

    Science.gov (United States)

    2010-01-01

    ... by a cooperator. (9) Carrier. A truck, trailer, truck/trailer(s) combination, railroad car, barge... provided in the agreement. (16) Department. The United States Department of Agriculture. (17) Factor. A... specific physical factors using approved equipment and an inspector's interpretation of visual...

  16. Dicty_cDB: SSC868 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 48 0.11 1 BQ596214 |BQ596214.1 PfESToab30g09.y1 Plasmodium falciparum 3D7 asexual cDNA Plasmodium falciparum... cDNA 5', mRNA sequence. 48 0.11 1 BI814440 |BI814440.1 PfESToaa22f12.y1 Plasmodium falciparum 3D7 asexual c...PfESToab03b07.y1 Plasmodium falciparum 3D7 asexual cDNA Plasmodium falciparum cDNA 5', mRNA sequence. 48 0.1...|AJ310823.1 Medicago truncatula genomic DNA, Sy4 locus. 48 0.11 1 BI815698 |BI815698.1 PfESToaa31f08.y1 Plasmodium falciparum 3D7 ase...xual cDNA Plasmodium falciparum cDNA 5', mRNA sequence.

  17. 31 CFR 8.68 - Decision of Administrative Law Judge.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Decision of Administrative Law Judge... Administrative Law Judge. As soon as practicable after the conclusion of a hearing and the receipt of any proposed findings and conclusions timely submitted by the parties, the Administrative Law Judge shall...

  18. Dicty_cDB: SHH868 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 87 |DR779687.1 BAAC-PNP1260K12.g1 C.remanei EST SB146 Caenorhabditis remanei cDNA 5, mRNA sequence. 48 0.24 ...1 DR777907 |DR777907.1 BAAC-PNP1255I09.g1 C.remanei EST SB146 Caenorhabditis remane

  19. Dicty_cDB: SHA868 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 863585.1 kx46a06.y1 Parastrongyloides trichosuri FL pAMP1 v1 Chiapelli McCarter Parastrongyloides trichosuri...2e-21 4 BI863575 |BI863575.1 kx45h07.y1 Parastrongyloides trichosuri FL pAMP1 v1 Chiapelli McCarter Parastrongyloides... BI451383 |BI451383.1 kx23e09.y1 Parastrongyloides trichosuri FL pAMP1 v1 Chiapelli McCarter Parastrongylo...ides trichosuri cDNA 5' similar to SW:EF2_CAEEL P29691 ELONGATION FACTOR 2 ;, mRNA ..., complete cds. 145 3e-86 8 X15386 |X15386.1 Dictyostelium discoideum H6 gene mRNA. 280 2e-75 2 BI863585 |BI

  20. Dicty_cDB: SHB868 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available |M26017.1 D.discoideum elongation factor 2 mRNA, complete cds. 482 e-154 2 CZ289188 |CZ289188.1 cp62f05.f Candida parapsilos...is Random Genomic Library Candida parapsilosis genomic clone cp6...2f05, genomic survey sequence. 64 1e-18 4 CZ291650 |CZ291650.1 cp76h06.f Candida parapsilosis Random Genomic Library Candida parapsil...1 cp27c04.f Candida parapsilosis Random Genomic Library Candida parapsilosis geno...s. 64 2e-17 3 AF107291 |AF107291.1 Candida parapsilosis elongation factor 2 (EFT2

  1. Dicty_cDB: VSC868 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 5171 ) ribosomal protein L7a [Takifugu rubripes], mRNA sequence. 60 3e-05 1 BQ476680 |BQ476680.1 curculio4h0...1.g Curculio glandium cDNA Curculio glandium cDNA clone curculio4h01 3', mRNA sequence. 54 3e-05 2 CA845440

  2. 7 CFR 868.212 - Special grades and requirements.

    Science.gov (United States)

    2010-01-01

    .... Tolerances for live insects for infested rough rice are defined according to sampling designations as follows...) of this section will be considered infested if the representative sample contains two or more live weevils, or one live weevil and one or more other live insects injurious to stored rice or five or...

  3. Dicty_cDB: VSI868 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available . 64 2e-06 1 BI892435 |BI892435.1 ZF637-3-001690 Zebrafish shield stage whole emb...BI892100 |BI892100.1 ZF637-3-001355 Zebrafish shield stage whole embryo cDNA library MPMGp637 Danio rerio cD.... 64 2e-06 1 BI887491 |BI887491.1 ZF637-1-001746 Zebrafish shield stage whole embryo cDNA library MPMGp637 D...anio rerio cDNA clone MPMGP637_2M24;MPMGP637M242 5', mRNA sequence. 64 2e-06 1 BI889320 |BI889320.1 ZF637-2-001075 Zebrafish shield... clone MPMGp637_23C2;MPMGp637C0223 5', mRNA sequence. 62 9e-06 1 CD053209 |CD053209.1 LITHZF000637 Zebrafish shield

  4. 21 CFR 868.1920 - Esophageal stethoscope with electrical conductors.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Esophageal stethoscope with electrical conductors... stethoscope with electrical conductors. (a) Identification. An esophageal stethoscope with electrical conductors is a device that is inserted into the esophagus to listen to a patient's heart and breath...

  5. 7 CFR 868.80 - Who may be licensed.

    Science.gov (United States)

    2010-01-01

    ...; and (3) Has no interest, financial or otherwise, direct or indirect in merchandising, handling... indirect in merchandising, handling, storing, or processing the kind of commodities or related products...

  6. Sensorless BLDC Motor Control Using C868%单片机C868实现无传感器BLDC电机控制

    Institute of Scientific and Technical Information of China (English)

    Zhang Qing; Jane Wang; David Lee

    2004-01-01

    BLDC具备诸多优势,例如外型紧凑、结构简单、高效率、低噪音、较长使用寿命等等,这种电机越来越广泛地应用于自动化、工业和消费类电子产品等领域。图1所示为典型的BLDC电机框图,该电机包括一个梯形磁通的永磁同步电机、一个转子位置检测器(通常为三个霍尔传感器)和一个驱动电机的三相逆变器。另

  7. Radio Channel Characterization of a Metal Bridge Segment at 868MHz and 2.4GHz

    NARCIS (Netherlands)

    Djapic, R.; Toh, Y.; Oostveen, J.C.

    2013-01-01

    Accurate radio channel modeling is essential for simulation and performance prediction of wireless sensor networks (WSNs). This paper presents results of radio channel measurements performed in a difficult propagation environment. In particular, signal path loss is measured in case transmit and rece

  8. Characterization and modeling of on-body spatial diversity within indoor environments at 868 MHz

    NARCIS (Netherlands)

    Cotton, S.L.; Scanlon, W.G.

    2009-01-01

    For the first time in the open literature we present a full characterization of the performance of receiver diversity for the on-body channels found in body area networks. The study involved three commonly encountered diversity combining schemes: selection combination (SC), maximal ratio combining (

  9. 21 CFR 868.2480 - Cutaneous carbon dioxide (PcCO2) monitor.

    Science.gov (United States)

    2010-04-01

    ... relative changes in a hemodynamically stable patient's cutaneous carbon dioxide tension as an adjunct to arterial carbon dioxide tension measurement. (b) Classification. Class II (special controls). The...

  10. 7 CFR 868.90 - Fees for certain Federal inspection services.

    Science.gov (United States)

    2010-01-01

    ....00 (5) Ash 17.00 (6) Brix 16.00 (7) Calcium 27.00 (8) Carotenoid Color 27.00 (9) Cold test (oil) 20.00 (10) Color test (syrups) 13.00 (11) Cooking tests (pasta) 13.00 (12) Crude fat 20.00 (13) Crude... Saturday, Sunday, and Holidays 44.40 Miscellaneous Processed Commodities: 2 (1) Additional Tests (cost...

  11. 7 CFR 868.315 - Special grades and special grade requirements.

    Science.gov (United States)

    2010-01-01

    ... safe and suitable as defined in the regulation issued pursuant to the Federal Food, Drug, and Cosmetic... has been gelatinized by soaking, steaming, and drying. Grades U.S. No. 1 to U.S. No. 6,...

  12. 21 CFR 868.1170 - Indwelling blood hydrogen ion concentration (pH) analyzer.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Indwelling blood hydrogen ion concentration (pH... Indwelling blood hydrogen ion concentration (pH) analyzer. (a) Identification. An indwelling blood hydrogen ion concentration (pH) analyzer is a device that consists of a catheter-tip pH electrode and that...

  13. 7 CFR 868.91 - Fees for certain Federal rice inspection services.

    Science.gov (United States)

    2010-01-01

    ...) (Rough or Brown rice) 36.60 (b) All other factors (per factor) (all rice) 17.60 Total oil and free fatty... inspection): (a) Rough rice $41.90 (b) Brown rice for processing 36.00 (c) Milled rice 26.00 Factor analysis for any single factor (per factor): (a) Milling yield (per sample) (Rough or Brown rice) 32.50 (b)...

  14. 单片机C868实现无传感器BLDC电机控制

    Institute of Scientific and Technical Information of China (English)

    ZhangQing; JaneWang; DavidLee

    2004-01-01

    BLDC具备诸多优势,例如外型紧凑、结构简单、高效率、低噪音、较长使用寿命等等,这种电机越来越广泛地应用于自动化、工业和消费类电子产品等领域。图1所示为典型的BLDC电机框图,该电机包括一个梯形磁通的永磁同步电机、一个转子位置检测器(通常为三个霍尔传感器)和一个驱动电机的三相逆变器。另

  15. 21 CFR 868.9 - Limitations of exemptions from section 510(k) of the Federal Food, Drug, and Cosmetic Act (the act).

    Science.gov (United States)

    2010-04-01

    ... hepatitis, tuberculosis, or myocardial infarction or to monitor therapy; (4) For assessing the risk of... immunoassay technology; or (c) The device is an in vitro device that is intended: (1) For use in the diagnosis... use in screening or diagnosis of familial or acquired genetic disorders, including inborn errors...

  16. Use of Bacillus pumilus CBMAI 0008 and Paenibacillus sp. CBMAI 868 for colour removal from paper mill effluent Emprego de Bacillus pumilus CBMAI 0008 e Paenibacillus sp. CBMAI 868 para remoção da cor do efluente da indústria papeleira

    Directory of Open Access Journals (Sweden)

    Patrícia Lopes de Oliveira

    2009-06-01

    Full Text Available Bacillus pumilus and Paenibacillus sp. were applied on the paper mill effluent to investigate the colour remotion. Inocula were individually applied in effluent at pH 7.0, 9.0 and 11.0. The real colour and COD remotion after 48h at pH 9.0 were, respectively, 41.87% and 22.08% for B. pumilus treatment and 42.30% and 22.89% for Paenibacillus sp. Gel permeation chromatography was used to verify the molar masses of compounds in the non-treated and treated effluent, showing a decrease in the compounds responsible for the paper mill effluent colour.Bacillus pumilus e Paenibacillus sp. foram aplicados separadamente no efluente da indústria papeleira a pH 7,0, 9,0 e 11,0, para verificação da remoção da cor e da DQO. As remoções da cor real e DQO após 48h a pH 9,0 foram, respectivamente, de 41,87% e 22,08% após o tratamento com B. pumilus e 42,30% e 22,89% após tratamento com Paenibacillus sp. As massas molares dos compostos presentes no efluente não tratado e tratado foram determinadas por cromatografia de permeação em gel. O emprego dos microrganismos reduziu os compostos responsáveis pela cor do efluente da indústria papeleira.

  17. 21 CFR Appendix B to Subpart B of... - Scope of Product Coverage

    Science.gov (United States)

    2010-04-01

    ... Radiographic Grid IXJ—Grid, Radiographic 892.1960 Radiographic Intensifying Screen EAM—Screen, Intensifying... interpretation calculator 2 868.2025 Ultrasonic air embolism monitor 2 868.2375 Breathing frequency monitor... densitometer 2 892.1200 Emission computed tomography system 2 892.1310 Nuclear tomography system 1...

  18. A Reaction Sphere for High Performance Attitude Control Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Our innovative reaction sphere (Doty pending patent application serial number 61/164,868) has the potential to provide much higher performance than a conventional...

  19. InterProScan Result: CK521350 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available CK521350 CK521350_4_ORF2 D91064CB8CADF868 PANTHER PTHR10605 HEPARAN SULFATE SULFOTR...ANSFERASE 1.5e-17 T IPR000863 unintegrated Molecular Function: sulfotransferase activity (GO:0008146) ...

  20. Dicty_cDB: VHD486 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available map 5817431-5836155 strain AX4, complete sequence. 74 2e-15 3 DT260079 |DT260079.1 JGI_CAAU9566.rev CAAU Pimephales promelas... brain 7-8 month adults, males and females pooled (L) Pimephales promelas cDNA clone CAAU956...6 3', mRNA sequence. 58 3e-04 1 DT355089 |DT355089.1 JGI_CABW868.fwd CABW Pimephales promelas ovary 7-8 mont...h adults, females pooled (M) Pimephales promelas cDNA clone CABW868 5', mRNA sequ...ence. 50 0.063 1 DT355088 |DT355088.1 JGI_CABW868.rev CABW Pimephales promelas ovary 7-8 month adults, femal

  1. A design and construction of 4 channel biotelemetry device employing indoor.

    Science.gov (United States)

    Fidan, Ugur; Güler, Nihal Fatma

    2007-06-01

    In this study, 4 channel biotelemetry device was designed and implemented for monitoring physiological and biological signals of the patients at indoor. Body temperature, respiratory rate, heart rate, electrocardiogram (ECG) and electromyogram (EMG) signals were transmitted using 10 mW 433 MHz and 500 mW 868 MHz FM/FSK transmitter with 9.6 Kps transmission speed. At indoor, receive signal strength indicator (RSSI) levels were measured and compared with 433 and 868 MHz carrier frequency. The placement of repeater at indoor was decided as a result of RSSI measurement.

  2. Palmyra Atoll Site 27P 9/21/2004 33-34M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 27P (05 52.868N, 162 02.529W), between 33 and 34 meters along a permanent transect.

  3. Draft Genome Sequence of Parabacteroides goldsteinii with Putative Novel Metallo-β-Lactamases Isolated from a Blood Culture from a Human Patient

    DEFF Research Database (Denmark)

    Krogh, Thøger Jensen; Agergaard, Charlotte Nielsen; Møller-Jensen, Jakob;

    2015-01-01

    Parabacteroides goldsteinii was isolated from a blood culture. Genomic DNA was sequenced using a MiSeq sequencer and assembled using the SPAdes genome assembler. The draft genome sequence was 6,851,868 bp, spanning 282 contigs of 5,253 coding sequences, 66 tRNAs, and 5 rRNAs. Several putative novel...

  4. Research on 3D Micro-nano Processing Reported on Nature

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ The latest issue of Nature reported in its Research Highlights ( see " Lithography: Luminous Lizards", Nature, Vol. 451, p868, Feb. 21, 2008) that a group of researchers from the Technical Institute of Physics and Chemistry (TIPC), Chinese Academy of Sciences (CAS) achieved the new progress in 3D microstructures of nanometer composites using the multiphoton nanoprocessing technology.

  5. Benzodiazepinordinationer i almen praksis. En analyse of forbrugsmønstret for førstegangsbrugere

    DEFF Research Database (Denmark)

    Bjerrum, L; Andersen, U A

    1996-01-01

    in Svendborg in 1990: n = 40,868). The incidence of first time users was 10 per 1000 person-years. Ninety percent of first time users seemed to be psychologically healthy persons. The most frequent indications were anxiety (1/3), insomnia (1/3), or crisis (1/4). After four years 98% of first time users had...

  6. Palmyra Atoll Site 27P 9/21/2004 38-39M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 27P (05 52.868N, 162 02.529W), between 38 and 39 meters along a permanent transect.

  7. [Serologic study of the diagnosis of Chagas disease in Nicaraguan students in the Juventud island].

    Science.gov (United States)

    Montes de Oca, N V; Cabrera Alonso, C; Martínez, R; Cantelar de Francisco, N; Pérez Insueta, O

    1989-01-01

    The results obtained during the serologic study for the diagnosis of Chagas' disease in 868 Nicaraguan students in the Isle of Youth are reported. Qualitative hemagglutination and indirect immunofluorescence were used. It was found that 8.5% of these students showed antibodies specific to Trypanosoma cruzi by means of this diagnostic test.

  8. Amino Acids in the TM4-TM5 loop of Na,K-ATPase Are Important for Biosynthesis

    DEFF Research Database (Denmark)

    Jørgensen, Jesper Roland; Houghton-Larsen, Jens; Jacobsen, Mette Dorph;

    2003-01-01

    -sensitive folding mutants, as they induce the unfolded protein response at 30°C but not at 15°C. We used an algorithm to predict that residues 868ENGFLIPIHLL878 in the L78 loop exposed to the endoplasmic reticulum lumen constitute the most likely BiP binding site. Correct folding of this sequence may be important...

  9. Deoxyribonucleic acid-binding ability of androgen receptors in whole cells: implications for the actions of androgens and antiandrogens

    NARCIS (Netherlands)

    C.W. Kuil (Cor); E. Mulder (Eppo)

    1996-01-01

    textabstractIn whole cells, the effects of several androgens and antiandrogens on the in the induction of DNA binding for the human wild-type androgen receptor (AR) and a mutant receptor ARL (LNCaP mutation; codon 868, Thr to Ala) were examined and related to the transc

  10. Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

    DEFF Research Database (Denmark)

    Stitziel, Nathan O; Stirrups, Kathleen E; Masca, Nicholas G D

    2016-01-01

    BACKGROUND: The discovery of low-frequency coding variants affecting the risk of coronary artery disease has facilitated the identification of therapeutic targets. METHODS: Through DNA genotyping, we tested 54,003 coding-sequence variants covering 13,715 human genes in up to 72,868 patients with ...

  11. Dicty_cDB: Contig-U15928-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available R012229 ) Sequence 4 from patent US 5763246. 34 3.4 4 ( DL168625 ) Methods for Identifying...868. 34 3.5 4 ( DL171459 ) Methods for Identifying the Target of a Compound ... 34 3.5 4 ( DJ377194 ) Identi

  12. Realization of Timed Reliable Communication over Off-The-Shelf Wireless Technologies

    DEFF Research Database (Denmark)

    Malinowsky, B.; Groenbaek, Jesper; Schwefel, Hans-Peter

    2013-01-01

    selfdeployed networks based on 868 MHz XBee communication and EDGE/UMTS cellular infrastructure networks. Link measurements are conducted using OTS components. The experimental tests show good results for the considered long-range practical scenarios, supporting our approach of using an analytical model...

  13. Palmyra Atoll Site 27P 9/21/2004 17-18M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 27P (05 52.868N, 162 02.529W), between 17 and 18 meters along a permanent transect.

  14. 77 FR 9893 - Notice of Scope Rulings

    Science.gov (United States)

    2012-02-21

    ... Bearings from the People's Republic of China. Requestor: New Trend Engineering Limited; its wheel hub units... Ltd.; its wheel hub units are within the scope of the antidumping duty order; June 14, 2011. A-570-803...-570-868: Folding Metal Tables and Chairs from the People's Republic of China. Requestor:...

  15. 76 FR 73596 - Notice of Scope Rulings

    Science.gov (United States)

    2011-11-29

    ... Bearings from the People's Republic of China Requestor: Blackstone OTR LLC and OTR Wheel Engineering, Inc.; its wheel hub units/assemblies with tapered roller bearings are within the scope of the antidumping duty order; February 7, 2011. A-570-868: Folding Metal Tables and Chairs from the People's Republic...

  16. Eesti riikliku arengukava toetused / Margus Palu

    Index Scriptorium Estoniae

    Palu, Margus

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 75-79. 2004. a esitati 1015 taotlust 868,7 mln krooni suruses summas, millest rahuldati 57% ehk 582 taotlust toetussummas 619,3 mln krooni

  17. Palmyra Atoll Site 27P 9/21/2004 41-42M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 27P (05 52.868N, 162 02.529W), between 41 and 42 meters along a permanent transect.

  18. El Arte de Aprender: Una Aventura Cooperativa. Un guia de recursos para trabajar con ninos jovenes. (Learning: A Cooperative Adventure. A Resource Guide for Working with Young Children.)

    Science.gov (United States)

    Arizona State Dept. of Education, Phoenix.

    Due to the large numbers of children from Spanish-speaking homes, many districts send both English and Spanish written communication to parents and community members. Therefore this booklet, a Spanish translation of "Learning: A Cooperative Adventure" (ED 119 868), was prepared to provide parents and preschool and kindergarten staff members with…

  19. Rationale for the Coadministration of Albendazole and Ivermectin to Humans for Malaria Parasite Transmission Control

    Science.gov (United States)

    2014-07-28

    elephant? Parasitology 135: 861–868. 62. Nacher M, 2011. Interactions between worms and malaria: good worms or bad worms? Malar J 10: e259. 63. Nacher M...Fenwick A, 2007. Parasitological impact of 2-year preventive chemotherapy on schistosomiasis and soil-transmitted helminthiasis in Uganda. BMC Med 5: e27

  20. Palmyra Atoll Site 27P 9/21/2004 4-5M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 27P (05 52.868N, 162 02.529W), between 4 and 5 meters along a permanent transect.

  1. Characterization of Beta-leptinotarsin-h and the Effects of Calcium Flux Antagonists on its Activity

    Science.gov (United States)

    2007-11-02

    channels. Biochemistry 23, 734–740. Davila, H.M., 1999. Molecular and functional diversity of voltage gated calcium channels. Annals NY Acad. Sci. 868...Pietrobon, D., 1996. Functional diversity of P-type and R-type calcium channels in rat cerebellar neurons. J. Neurosci. 16, 6353–6363. Uchitel, O.D

  2. Domain Modeling: NP_002244.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_002244.1 chr4 cFMS tyrosine kinase (tie2 KID) in complex with a pyrimidinopyrido...ne inhibitor p3beaa_ chr4/NP_002244.1/NP_002244.1_holo_806-1174.pdb blast 840L,841G,848V,866A,868K,899V,916V

  3. Curriculum for Junior High School Students: Dairy Food Consumption Self-Efficacy

    Science.gov (United States)

    Pobocik, Rebecca S.; Haar, Christine M.; Dawson, Erin E.; Coleman, Priscilla; Bakies, Karen

    2009-01-01

    A nutrition education module for a family and consumer sciences curriculum was developed and evaluated with junior high school students (n = 63) using a quasi-experimental design. The multivariate interaction between time of measurement and intervention was significant, F (2, 50) = 8.68, p = 0.001.The univariate interaction between pre and post…

  4. Interference Impact on Coverage and Capacity for Low Power Wide Area IoT Networks

    DEFF Research Database (Denmark)

    Vejlgaard, Benny; Lauridsen, Mads; Nguyen, Huan Cong;

    2017-01-01

    In this paper we analyze and discuss the coverage and capacity of Sigfox and LoRaWAN in a large scale urban environments covering 150 km2 in Northern Denmark. First, the study measures and analyzes interference in the European 868 MHz license free industrial, scientific, and medical band, creatin...

  5. ADHD Is Associated with a "Western" Dietary Pattern in Adolescents

    Science.gov (United States)

    Howard, Amber L.; Robinson, Monique; Smith, Grant J.; Ambrosini, Gina L.; Piek, Jan P.; Oddy, Wendy H.

    2011-01-01

    Objective: To examine the relationship between dietary patterns and ADHD in a population-based cohort of adolescents. Method: The Raine Study is a prospective study following 2,868 live births. At the 14-year follow-up, the authors collected detailed adolescent dietary data, allowing for the determination of major dietary patterns using factor…

  6. Early Development of the Low SES Infant Weighing Less Than 1001 Grams at Birth.

    Science.gov (United States)

    Finello, Karen M.; And Others

    To evaluate outcomes in infants of very low birth weight born in 1982-83 to families of extremely low socioeconomic status (SES), 33 infants who weighed less than 1001 grams at birth and survived the nursery period were followed for 1 year. The sample was 79 percent Hispanic and 58 percent female. Mean birth weight was 868 grams and mean…

  7. 76 FR 59391 - Notice of Availability of Government-Owned Inventions; Available for Licensing

    Science.gov (United States)

    2011-09-26

    ... Improving the Efficiency and Reliability of a Broadband Transistor Switch for Periodic Switching... Issued 1/4/2011/ /U.S. Patent No. 7,868,833: An Ultra Wideband Buoyant Cable Antenna Element Issued 1/11..., Alternate Federal Register Liaison Officer. BILLING CODE 3810-FF-P...

  8. Characterization of resistance gene analogues (RGAs) in Apple (Malus 6domestica Borkh.) and their evolutionary history of the Rosaceae family

    Science.gov (United States)

    The family of resistance gene analogues (RGAs) with a nucleotide-binding site (NBS) domain accounts for the largest number of disease resistance genes and is one of the largest gene families in plants. We have identified 868 RGAs in the genome of the apple (Malus × domestica Borkh.) cultivar ‘Golden...

  9. Genome wide association analysis for residual feed intake in Danish Duroc boars

    DEFF Research Database (Denmark)

    Do, Duy Ngoc; Ostersen, Tage; Strathe, Anders Bjerring;

    2013-01-01

    gain (30-100 kg). RFI2 was the same as RFI1 except that it was also regressed on backfat (BF). A total of 868 boars had phenotypic and genotype (i.e. Illumina Porcine SNP60 BeadChip) records. A total of 33945 SNPs were available for genome wide association studies (GWAS) after quality control...

  10. Palmyra Atoll Site 27P 9/21/2004 46-47M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 27P (05 52.868N, 162 02.529W), between 46 and 47 meters along a permanent transect.

  11. Dicty_cDB: VSE444 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available (bits) Value N D37981 |D37981.1 Dictyostelium discoidium DDCOF2 gene for cofilin, complete cds. 868 0.0 1 D3...7980 |D37980.1 Dictyostelium discoidium DDCOF1 gene for cofilin, complete cds (ex

  12. InterProScan Result: FS848273 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS848273 FS848273_2_ORF2 305523EE868DDB0C PANTHER PTHR10520 PHOSPHORIBOSYLAMINE-GLYCINE... LIGASE-RELATED 3.1e-19 T IPR020562 unintegrated Molecular Function: phosphoribosylamine-glycine ligase

  13. InterProScan Result: FS848273 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS848273 FS848273_2_ORF2 305523EE868DDB0C PANTHER PTHR10520:SF3 PHOSPHORIBOSYLAMINE--GLYCINE... LIGASE 3.1e-19 T IPR020562 unintegrated Molecular Function: phosphoribosylamine-glycine ligase act

  14. CO2NSL (Datalogger)

    DEFF Research Database (Denmark)

    Andersen, Sune Sick

    MESH network(868 Mhz) to a database server for later analyze. The Prototype is developed on two microcontrollers(AVR and ARM Cortex-A8) with the low power and with fault tolerant in mind, equipped with extra storage for offline catching(like a uSD(16/32Gb)).The ARM CortexA8-board is running a full...

  15. Navy Warfare Development Command’s NEXT Magazine, Spring 2014 Edition. Volume 2, Number 1

    Science.gov (United States)

    2014-05-01

    seventy- one players registered. contributing 2.868 idea card.s and 23 accion plans outlining Pl)(ential ideas. The action plans described Pl...forth in his Navigation Plan . and I hope you enjoy reading about them in this issue and help us funher these initiatives through your feedback and...4243 James Seen:lon Director (757) 341-4183 Mar\\ Henning Director, l esSon$ l earned (757) 341-42 12 Aeet Training . In tegration. and Planning

  16. 元宝草培养物的总黄酮含量%Total flavonoid contents in cultural materials of Hypericum sampsonii Hance

    Institute of Scientific and Technical Information of China (English)

    曾虹燕; 周朴华; 裴刚

    2002-01-01

    The total flavonoid contents in cultural materials and natural plant of Hypericum sampsonii Hance were analysed and compared with that in cultural materials of H. Perforatum Linn. The results showed that the total flavonoid contents reached 5.416%-5.868% in H. Sampsonii calli cultured for 30 d, which were higher than that of natural plant of this species (4.325%-4.527%) and approached to cultural materials of H. Perforatum.

  17. Hybrid silicon nanocrystal-organic light-emitting devices for infrared electroluminescence.

    Science.gov (United States)

    Cheng, Kai-Yuan; Anthony, Rebecca; Kortshagen, Uwe R; Holmes, Russell J

    2010-04-14

    We demonstrate hybrid inorganic-organic light-emitting devices with peak electroluminescence (EL) at a wavelength of 868 nm using silicon nanocrystals (SiNCs). An external quantum efficiency of 0.6% is realized in the forward-emitted direction, with emission originating primarily from the SiNCs. Microscopic characterization indicates that complete coverage of the SiNCs on the conjugated polymer hole-transporting layer is required to observe efficient EL.

  18. Multi-Band Cable Antenna with Irregular Reactive Loading

    Science.gov (United States)

    2014-11-04

    Attorney Docket No. 300035 5 August 15 The below identified patent application is available for licensing. Requests for information should be...of any royalties thereon or therefor. CROSS REFERENCE TO OTHER PATENT APPLICATIONS [0002] None. BACKGROUND OF THE INVENTION (1) Field of the...U.S. Patent No. 7,868,833, entitled “Ultra wideband buoyant cable antenna element.” This improvement was only possible in a single portion of the

  19. Immobilisation of manganese, cobalt and nickel by deep-sea-sediment microbial communities

    Digital Repository Service at National Institute of Oceanography (India)

    Sujith, P.P.; Das, A.; Mourya, B.S.; LokaBharathi, P.A.

    oxidizing bacterial isolates from the Indian Ridge system. TBC correlated positively and TOC negatively with depth (r = 0.868, p < 0.001 and r = 0.666, p < 0.05) respectively. These observations suggest that microbial abundance, the diversity.... The present results agree with previous studies [43-47] which reported positive correlation between heavy metal concentrations and the percentage of bacteria resistant to metals in different soils and sediments. However, maximum Ni immobilization (6 ± 0...

  20. Association of 2184AG Polymorphism in the RAGE Gene with Diabetic Nephropathy in Chinese Patients with Type 2 Diabetes

    OpenAIRE

    Wei Cai; Jian Li; Ji-Xiong Xu; Ying Liu; Wei Zhang; Jun-Ren Xiao; Ling-Yan Zhu; Jian-Ying Liu

    2015-01-01

    Objective. The interaction between advanced glycation end products and their cellular receptor (RAGE) has an important role in the pathogenesis of diabetic microvascular complications. The aim of this study was to investigate the relationship between the 2184A/G polymorphism in the RAGE gene and diabetic nephropathy in Chinese Han patients with type 2 diabetes mellitus. Methods. A total of 868 patients with type 2 diabetes mellitus (486 without and 382 with diabetic nephropathy) were enrolled...

  1. AGN X-Ray emission and black holes (Kelly+, 2008)

    DEFF Research Database (Denmark)

    Kelly, B. C.; Bechtold, J.; Trump, J. R.

    2009-01-01

    In this analysis we combine 169 RQQs from Kelly et al. (2007ApJ...665.1489K) with 149 RQQs from the main SDSS sample of Strateva et al. (2005, Cat. J/AJ/130/387) to create a sample of 318 RQQs. Out of these 318 sources, 276 (86.8%) are detected in the X-ray. (1 data file)....

  2. Bulk Shielding Facility quarterly report, July, August, and September of 1977

    Energy Technology Data Exchange (ETDEWEB)

    Hurt, S.S. III; Lance, E.D.; Thomas, J.R.

    1978-02-01

    The BSR operated at an average power level of 1,868 kW for 23.58 percent of the time during July, August, and September. Water-quality control in both the reactor primary and secondary cooling systems was satisfactory. The PCA was used in training programs and was operated on two occasions when the Oak Ridge Associated Universities' students actively participated in training laboratories.

  3. Data of evolutionary structure change: 1CNYA-1RJ5B [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available -7.732 14.011 15.259 1.00 14.49 C -map> PHE ASP GLY TYR LYS THR ... PHE CA -map> VAL CA 540 HIS CA 529 TR... ATOM 3045 CA LEU B 131 19.494 9.945 -22.868 1.00 53.30 C ... CA 3.79 LEU CA -map> VAL CA 537 -map>

  4. A Compilation of Hazard and Test Data for Pyrotechnic Compositions

    Science.gov (United States)

    1980-10-01

    Lead thiocynate 33 25 Lead azide 5 29 20 Carborundum 5 Barium nitrate 20 39 Basic lead styphnate 40 Tetrocene 5 2 Lead styphnate (normal) 38 Lead...Basic leas styphnate 53 60 Tetracene 5 5 5 , 3.1 12 4 Barium nitrate 20 25 8.68 31 22 32 Aluminum 10 7 Lead thiocynate 38.18 25 17 Ground glass...4) COMPOSITION: SENSITIVITY: Ingredients Lead Azide Basic Lead Styphnate Tetracene Barium Nitrate Antinomy

  5. VizieR Online Data Catalog: AGN X-Ray emission and black holes (Kelly+, 2008)

    Science.gov (United States)

    Kelly, B. C.; Bechtold, J.; Trump, J. R.; Vestergaard, M.; Siemiginowska, A.

    2009-07-01

    In this analysis we combine 169 RQQs from Kelly et al. (2007ApJ...665.1489K) with 149 RQQs from the main SDSS sample of Strateva et al. (2005, Cat. J/AJ/130/387) to create a sample of 318 RQQs. Out of these 318 sources, 276 (86.8%) are detected in the X-ray. (1 data file).

  6. Assessing Security Cooperation as a Preventive Tool

    Science.gov (United States)

    2014-01-01

    MG-868-AF, 2010. 49 Edward Thomas Rowe, “Aid and Coups d’Etat: Aspects of the Impact of American Mili- tary Assistance Programs in the Less Developed...development assistance and state fragility was beyond the scope of this project. 9 Jack A. Goldstone, Robert H. Bates, David L. Epstein , Ted Robert...Gurr, Michael B. Lustik, Monty G. Marshall, Jay Ulfelder, and Mark Woodward, “A Global Model for Fore- casting Political Instability,” American Journal

  7. A detector to search for antiproton decay at the Fermilab antiproton accumulator

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, T. [Pennsylvania State Univ., University Park, PA (United States); Buchanan, C.; Corbin, B.; Lindgren, M.; Muller, T.; Scott, A. [University of California at Los Angeles, Los Angeles, CA 90024 (United States); Geer, S.; Marriner, J.; Martens, M.; Ray, R.; Streets, J.; Wester, W. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Gustafson, R. [University of Michigan, Ann Arbor, MI 48109 (United States); Hu, M.; Snow, G.R. [University of Nebraska-Lincoln, Lincoln, NE (United States); APEX Collaboration

    1998-07-11

    We describe the experimental apparatus used by the APEX experiment (Experiment 868) at the Fermilab antiproton accumulator. The experiment is designed to search for decays of 8.9 GeV/c antiprotons as they traverse a 3.7 m long evacuated decay tank inserted in a straight section of the antiproton accumulator ring. The detector components in the experimental set-up are discussed individually, and the performance of the experiment during data-taking is described. (orig.)

  8. QoS measurement of Zigbee home automation network using various modulation schemes

    Directory of Open Access Journals (Sweden)

    Gurjit Kaur,

    2011-02-01

    Full Text Available Increased demands on implementation of wireless sensor networks in automation praxis resulted in relatively new wireless standard – Zigbee. The IEEE 802.15.4 standard specifies the multiple PHYs for 868, 915 and 2400 MHz three frequency bands. In this paper we presents the performance analysis of different modulation schemesat different frequency range like ASK, BPSK and QPSK at 868, 915 & 2400 MHz based on their effect on the quality of service parameter by using CBR application in Zigbee home automation network using static IEEE 802.15.4. The QoS parameters such as average end-to-end delay, jitter, and throughput are investigated as the performance metrics. The results show that even though ASK at 868 MHz gives the highest throughput of 100% which is highest amongst all five modulation schemes but still overall ASK at 915 MHz is the best suited modulation schemes for CBR application of Zigbee home automation since it produced lowest jitter value of 0.03s and lowest average end-to-end delay value of 3.30s which are both favorable conditions for better performance of CBR application of Zigbee home automation network.

  9. Non-Linguistic Vocal Event Detection Using Online Random

    DEFF Research Database (Denmark)

    Abou-Zleikha, Mohamed; Tan, Zheng-Hua; Christensen, Mads Græsbøll

    2014-01-01

    Accurate detection of non-linguistic vocal events in social signals can have a great impact on the applicability of speech enabled interactive systems. In this paper, we investigate the use of random forest for vocal event detection. Random forest technique has been successfully employed in many ...... show that according to the Area Under Curve measure the online random forest achieved 88.1% compared to 82.9% obtained by the baseline support vector machines for laughter classification and 86.8% to 83.6% for filler classification....

  10. Addressing Counterfeit Parts in the DoD Supply Chain

    Science.gov (United States)

    2013-04-01

    supply chain and affecting weapon system reliability. OTE data revealed that 39% of companies and organizations participating in the survey encountered counterfeit electronics during the four-year study period. Moreover, the frequency of detected counterfeit incidents was escalating rapidly, rising from 3,868 incidents in 2005 to 9,356 incidents in 2008. These counterfeit incidents included multiple versions of DoD qualified parts and components. Today, the DoD procures systems and products from a large network of global suppliers and manages over four million different

  11. A Multi-Frequency RFID Tag for Packaging Box%一种包装箱应用的多频段RFID标签

    Institute of Scientific and Technical Information of China (English)

    赖晓铮; 刘焕彬; 张瑞娜; 赖声礼

    2008-01-01

    针对在全球供应链应用中,"RFID包装箱"必须适应各国RFID频谱规范的问题,设计并制作了一种多频段RFID标签.RFID标签采用纸质材料作为标签基材,天线结构为耦合馈电结构.仿真和测量结果表明,此RFID标签能同时适用于欧盟RFID频谱(866~868MHz)和美洲RFID频谱(902~928MHz),适合"RFID包装箱"应用.

  12. The Seated Soldier Study: Posture and Body Shape in Vehicle Seats

    Science.gov (United States)

    2013-10-31

    blades, on spine, max anterior pt)* Standing 26 Height of Chest (max anterior pt) Standing 6.4.27 27 Waist Circumference at Omphalion Standing 6.4.88...28 Waist Height at Omphalion Standing 6.4.91 29 Bispinous Breadth Standing 30 Bicristal Breadth Standing 6.4.11 31 Hip Circumference at Buttocks...128 6 Waist Circumference (Omphalion) 732 819 868 916 1025 879 106 Waist Height (Omphalion) 907 951 970 997 1070 978 59 Weight (kg) 57 62 68 74 77 69

  13. Estrategias de aprendizaje y hábitos de estudio en el nivel superior: Diferencias según el año de cursado

    OpenAIRE

    Nancy Malander

    2014-01-01

    Esta investigación se propuso identificar si las estrategias de aprendizaje y hábitos de estudio de los alumnos de nivel superior varían según el año de cursado; y detectar aquellas estrategias que son utilizadas en forma deficiente por los alumnos, principalmente los de primer año. Se aplicó el Learning and Study Strategies Inventory (LASSI) a 115 alumnos de nivel superior (ME edad= 21,76; DE= 3,868). Se encontraron diferencias estadísticamente significativas en las siguientes dimensiones de...

  14. Susceptibility of meropenem and comparators tested against 30,634 Enterobacteriaceae isolated in the MYSTIC Programme (1997-2003).

    Science.gov (United States)

    Turner, Philip J

    2004-12-01

    A total of 30,634 global Enterobacteriaceae isolates collected from the MYSTIC (Meropenem Yearly Surveillance Test Information Collection) Programme were tested using a reference methodology against meropenem and seven other broad-spectrum agents commonly used in the hospital setting (1997-2003). The most active compound was meropenem (99.6% susceptible), followed by imipenem (98.4%), cefepime (94.0%), gentamicin (86.8%), piperacillin/tazobactam (85.8%), ceftazidime (85.0%), ciprofloxacin (84.6%), and tobramycin (84.5%). Continued surveillance of antimicrobial compounds' in vitro activity is necessary to recommend regimens that are likely to be effective in clinical practice.

  15. Compartmental and enzyme kinetic modeling to elucidate the biotransformation pathway of a centrally acting antitrypanosomal prodrug.

    Science.gov (United States)

    Generaux, Claudia N; Ainslie, Garrett R; Bridges, Arlene S; Ismail, Mohamed A; Boykin, David W; Tidwell, Richard R; Thakker, Dhiren R; Paine, Mary F

    2013-02-01

    DB868 [2,5-bis [5-(N-methoxyamidino)-2-pyridyl] furan], a prodrug of the diamidine DB829 [2,5-bis(5-amidino-2-pyridyl) furan], has demonstrated efficacy in murine models of human African trypanosomiasis. A cross-species evaluation of prodrug bioconversion to the active drug is required to predict the disposition of prodrug, metabolites, and active drug in humans. The phase I biotransformation of DB868 was elucidated using liver microsomes and sandwich-cultured hepatocytes from humans and rats. All systems produced four NADPH-dependent metabolites via O-demethylation (M1, M2) and N-dehydroxylation (M3, M4). Compartmental kinetic modeling of the DB868 metabolic pathway suggested an unusual N-demethoxylation reaction that was supported experimentally. A unienzyme Michaelis-Menten model described the kinetics of M1 formation by human liver microsomes (HLMs) (K(m), 11 μM; V(max), 340 pmol/min/mg), whereas a two-enzyme model described the kinetics of M1 formation by rat liver microsomes (RLMs) (K(m1), 0.5 μM; V(max1), 12 pmol/min/mg; K(m2), 27 μM; V(max2), 70 pmol/min/mg). Human recombinant CYP1A2, CYP3A4, and CYP4F2, rat recombinant Cyp1a2 and Cyp2d2, and rat purified Cyp4f1 catalyzed M1 formation. M2 formation by HLMs exhibited allosteric kinetics (S(50), 18 μM; V(max), 180 pmol/mg), whereas M2 formation by RLMs was negligible. Recombinant CYP1A2/Cyp1a2 catalyzed M2 formation. DB829 was detected in trace amounts in HLMs at the end of the 180-min incubation and was detected readily in sandwich-cultured hepatocytes from both species throughout the 24-h incubation. These studies demonstrated that DB868 biotransformation to DB829 is conserved between humans and rats. An improved understanding of species differences in the kinetics of DB829 formation would facilitate preclinical development of a promising antitrypanosomal prodrug.

  16. Mu‘tazilah and the Modernization of the Indonesian Muslim Community: Intellectual Portrait of Harun Nasution

    Directory of Open Access Journals (Sweden)

    Saiful Mujani

    2014-05-01

    Full Text Available Harun Nasution was born on 23rd September 1919 in Southern Tapanuli, North Sumatra and came from an elite family of his region. HIs father, Abdul Jabbar Ahmad, went on a pilgrimage to Mecca when he was very young. When he grew up he become successful trader, or more precisely an importer of some commodities from Singapore. It was a rare phenomenon in a colonial times for an Indonesian native to become a successful trader.Copyright (c 2014 by SDI. All right reserved.DOI: 10.15408/sdi.v1i1.868

  17. A Systems Biology Approach to Link Nuclear Factor Kappa B Activation with Lethal Prostate Cancer

    Science.gov (United States)

    2014-05-01

    throughput functional genomic data. Nucleic acids research 2009;37:D885-90. 3. Parkinson H, Kapushesky M, Kolesnikov N, et al. ArrayExpress update--from...an archive of functional genomics experiments to the atlas of gene expression. Nucleic acids research 2009;37:D868-72. 4. Breitkreutz BJ, Stark C...Reguly T, et al. The BioGRID Interaction Database: 2008 update. Nucleic acids research 2008;36:D637-40. 5. Kerrien S, Alam-Faruque Y, Aranda B, et al

  18. A study on consumer switching behaviour in cellular service provider

    OpenAIRE

    M. Sathish; K.J.Naveen; V.Jeevanantham

    2011-01-01

    Indian mobile market is a fastest growing market and is forecasted to reach 868.47 million users by 2013. India has seen rapid increase in number of players which caused the tariff rates to hit an all time low. This allowed the players to target the low income population increasing the market share. The availability of number of subscriber options for consumers and varied tariff rates of each player, lead the consumers to switch the service providers. The objectives of the study are to find t...

  19. Remote controlled gate controller using a GSM network and Arduino platform

    Directory of Open Access Journals (Sweden)

    Pospisilik Martin

    2016-01-01

    Full Text Available Most remote controllers for entrance gates operate on free frequencies 433 or 868 MHz. However, this technology limits the user comfort, as it is usually not common that bi-directional communication is established. A higher comfort of controlling the entrance gates can be achieved by employing the GSM network for transmission of commands and messages between the gate controller and the user. In this case, only a conventional GSM cellular phone is needed to control the gate. A description of such a controller based on the GSM module and Arduino controller is provided in this paper.

  20. Measurement of hadron and lepton pair production at 161 GeV < $\\sqrt{s}$ < 172 GeV at LEP

    CERN Document Server

    Acciarri, M; Aguilar-Benítez, M; Ahlen, S P; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alverson, G; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Baksay, L; Banerjee, S; Banerjee, Sw; Banicz, K; Barczyk, A; Barillère, R; Barone, L; Bartalini, P; Baschirotto, A; Basile, M; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Bilei, G M; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böck, R K; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brigljevic, V; Brock, I C; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Busenitz, J K; Button, A M; Cai, X D; Campanelli, M; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada-Canales, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chekanov, S V; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chéreau, X J; Chiefari, G; Chien, C Y; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Cohn, H O; Coignet, G; Colijn, A P; Colino, N; Commichau, V; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Dai, T S; D'Alessandro, R; De Asmundis, R; Degré, A; Deiters, K; Della Volpe, D; Denes, P; De Notaristefani, F; DiBitonto, Daryl; Diemoz, M; Van Dierendonck, D N; Di Lodovico, F; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Duinker, P; Durán, I; Dutta, S; Easo, S; Efremenko, Yu V; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ernenwein, J P; Extermann, Pierre; Fabre, M; Faccini, R; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Fenyi, B; Ferguson, T; Ferroni, F; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Fredj, L; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Goldfarb, S; Goldstein, J; Gong, Z F; Gougas, Andreas; Gratta, Giorgio; Grünewald, M W; Gupta, V K; Gurtu, A; Gutay, L J; Hartmann, B; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Van Hoek, W C; Hofer, H; Hong, S J; Hoorani, H; Hou, S R; Hu, G; Innocente, Vincenzo; Jenkes, K; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Kasser, A; Khan, R A; Kamrad, D; Kamyshkov, Yu A; Kapustinsky, J S; Karyotakis, Yu; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, D H; Kim, J K; Kim, S C; Kim, Y G; Kinnison, W W; Kirkby, A; Kirkby, D; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopp, A; Korolko, I; Koutsenko, V F; Krämer, R W; Krenz, W; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lapoint, C; Lassila-Perini, K M; Laurikainen, P; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Leonardi, E; Levchenko, P M; Li Chuan; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lu, W; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Majumder, G; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mangla, S; Marchesini, P A; Marin, A; Martin, J P; Marzano, F; Massaro, G G G; McNally, D; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mi, Y; Mihul, A; Van Mil, A J W; Mirabelli, G; Mnich, J; Molnár, P; Monteleoni, B; Moore, R; Morganti, S; Moulik, T; Mount, R; Müller, S; Muheim, F; Muijs, A J M; Nahn, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nippe, A; Nisati, A; Nowak, H; Oh, Yu D; Opitz, H; Organtini, G; Ostonen, R; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Park, H K; Park, I H; Pascale, G; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Peach, D; Pei, Y J; Pensotti, S; Perret-Gallix, D; Petersen, B; Petrak, S; Pevsner, A; Piccolo, D; Pieri, M; Pinto, J C; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Produit, N; Prokofev, D; Prokofiev, D O; Rahal-Callot, G; Raja, N; Rancoita, P G; Rattaggi, M; Raven, G; Razis, P A; Read, K; Ren, D; Rescigno, M; Reucroft, S; Van Rhee, T; Riemann, S; Riles, K; Robohm, A; Rodin, J; Roe, B P; Romero, L; Rosier-Lees, S; Rosselet, P; Van Rossum, W; Roth, S; Rubio, Juan Antonio; Ruschmeier, D; Rykaczewski, H; Salicio, J; Sánchez, E; Sanders, M P; Sarakinos, M E; Sarkar, S; Sassowsky, M; Sauvage, G; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schmitz, P; Scholz, N; Schopper, Herwig Franz; Schotanus, D J; Schultze, K; Schwenke, J; Schwering, G; Sciacca, C; Sciarrino, D; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shukla, J; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Sopczak, André; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stone, H; Stoyanov, B; Strässner, A; Strauch, K; Sudhakar, K; Sultanov, G G; Sun, L Z; Susinno, G F; Suter, H; Swain, J D; Tang, X W; Tauscher, Ludwig; Taylor, L; Ting, Samuel C C; Ting, S M; Tonutti, M; Tonwar, S C; Tóth, J; Tully, C; Tuchscherer, H; Tung, K L; Uchida, Y; Ulbricht, J; Uwer, U; Valente, E; Van de Walle, R T; Vesztergombi, G; Vetlitskii, I; Viertel, Gert M; Vivargent, M; Völkert, R; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M; Wallraff, W; Wang, J C; Wang, X L; Wang, Z M; Weber, A; Wittgenstein, F; Wu, S X; Wynhoff, S; Xu, J; Xu, Z Z; Yang, B Z; Yang, C G; Yao, X Y; Ye, J B; Yeh, S C; You, J M; Zalite, A; Zalite, Yu; Zemp, P; Zeng, Y; Zhang, Z; Zhang, Z P; Zhou, B; Zhu, G Y; Zhu, R Y; Zichichi, Antonino; Ziegler, F

    1997-01-01

    We report on measurements of $\\mathrm{e^+e^-}$ annihilation into hadrons and lepton pairs. The data have been taken with the L3 detector at LEP at centre--of--mass energies between 161~$\\mathrm{Ge\\kern -0.12em V}$ and 172~$\\mathrm{Ge\\kern -0.12em V}$. In a data sample corresponding to 21.2~pb$^{-1}$ of integrated luminosity 2728 hadronic and 868 lepton--pair events are selected. The measured cross sections and leptonic forward--backward asymmetries agree well with the Standard Model predictions. \\end{abstract}

  1. Monte Carlo calculations support organ sparing in Deep-Inspiration Breath-Hold intensity-modulated radiotherapy for locally advanced lung cancer

    DEFF Research Database (Denmark)

    Ottosson, Wiviann; Sibolt, Patrik; Larsen, Christina

    2015-01-01

    Background and purpose: Studies indicate that Deep-Inspiration Breath-Hold (DIBH) is advantageous over Free-Breathing (FB) for locally advanced lung cancer radiotherapy. However, these studies were based on simplified dose calculation algorithms, potentially critical due to the heterogeneous nature......) for intensity-modulated-radio therapy or volumetric-modulated-arc-therapy using 66 Gy in 33 fractions. All plans were re-calculated with MC. Results: Relative to FB, the total lung volume increased 86.8% in DIBH, while the gross tumor volume decreased 14.8%. MC revealed equally under- and over...

  2. KEBANGKRUTAN VERSUS RESTRUKTURISASI: EVALUASI DAN PREDIKSI KELANGSUNGAN HIDUP PERUSAHAAN PASCA KRISIS KEUANGAN 1997

    Directory of Open Access Journals (Sweden)

    Hermeindito Kaaro

    2016-11-01

    models are robust. The models provide highly accurate results in matching the classifications of actual observations and the prediction results, range from 86,8% through 100%. Fourth, four strategic attributes, the change of director boards, the composition change of capital ownerships, strategic alliances, and acquisitions, are effective to increase the firm performance. However, surprise that debt restructuring is less powerful to cope with the firm financial distress during three year periods of analysis. Keywords: healthy firm, debt restructuring, corporate strategy, business and financial risks

  3. The Microstructure and Mechanical Properties Study of Nickel Based Transition Dissimilar Steel Joints at Different PWHT Condition%镍基过渡异种钢焊接头在不同热处理状态下的性能研究

    Institute of Scientific and Technical Information of China (English)

    刘鸿国; 李太江; 刘福广; 王彩侠; 陈吉刚

    2009-01-01

    采用力学性能测试、高温持久试验、光学金相组织观察、扫描电子显微镜等方法,研究了T22+TP347H镍基过渡焊接接头不同热处理状态的组织与性能变化,得出了T22+TP347H焊接接头不论是否进行热处理,都可以达到DL/T 868-2004工艺评定要求等几项结论.

  4. Dissecting the Role of IGFBP-2 in Development of Acute Myeloid Leukemia

    Science.gov (United States)

    2011-06-01

    J  Mol  Endocrinol,  2004.  32(3):  p.  859-­‐68.   9.   Moore ,  M.G.,  et  al.,  Novel  stimulatory  role  for...K01CA120099, the Michael L. Rosenberg Endowed Scholar Fund from University of Texas Southwestern Medical Center, Basil O’Connor Award from the March of...Mol Endocrinol. 2004;32(3):859- 868. 10. Moore MG, Wetterau LA, Francis MJ, Peehl DM, Cohen P. Novel stimulatory role for insulin-like growth factor

  5. Visual Impairment as a Function of Visual Acuity in Both Eyes and Its Impact on Patient Reported Preferences

    OpenAIRE

    Finger, Robert P.; Eva Fenwick; Hirneiss, Christoph W.; Arthur Hsueh; Robyn H Guymer; Lamoureux, Ecosse L.; Jill E Keeffe

    2013-01-01

    PURPOSE: To assess the impact of VA loss on patient reported utilities taking both eyes into account compared to taking only the better or the worse eye into account. METHODS: In this cross-sectional study 1085 patients and 254 controls rated preferences with the generic health-related (EQ-5D; n = 868) and vision-specific (Vision and Quality of Life Index (VisQoL); n = 837) multi-attribute utility instruments (MAUIs). Utilities were calculated for three levels of VA in the better and worse ey...

  6. The Effect of Prolonged Military Activities in Man. Physiological and Biochemical Changes. Possible Means of Rapid Recuperation (les Effets d’activites mi1itaires prolongees sur l’homme. Changements physiologiques et biochimiques. Moyens possibles de recuperation rapide.)

    Science.gov (United States)

    2001-03-01

    intravenous infusion of isotonic saline solution. J Clin Invest 30:862 - 868, 1951. 39. Vedovato M., De Paoli Vitali E., Guglielmini C., Casoni I., Ricci G...failure in the rainy season. In the Sahel , the dry season is divided in a cool season in January and February and a hot or very hot season in April, May...36) A. Montmayeur, A. Buguet, H. Sollin and J. R. Lacour - Exercise and sleep in four African sportsmen living in the Sahel : a pilot study. Int. J

  7. Forbedret overlevelse hos børn med neuroblastom

    DEFF Research Database (Denmark)

    Schrøder, Henrik; Wacher, Jeanette; Larsson, Heidi;

    2010-01-01

    children below 15 years of age with neuroblastoma or ganglioneuroblastoma who were diagnosed in Denmark between 1981 and 2005. RESULTS: The incidence was 8.68 per million children below 15 years of age (world standard 9.6) and 43.5 per million children below 12 months of age and these incidences have...... three years from diagnosis occurred in only 2% of patients. The median time from relapse to death was three months. CONCLUSION: The survival of children with neuroblastoma in Denmark has increased significantly over the last 25 years. Udgivelsesdato: 2010-Oct-4...

  8. Polarity Control and Doping in Aluminum Gallium Nitride

    Science.gov (United States)

    2013-06-01

    seems to go hand in hand with a decrease in resistivity. In other words, a more activated sample shows a more intense ABX transition as well as a...Al0.8Ga0.2N grown on c- oriented AlN single crystal substrates; Physica Status Solidi (c) 9 (3-4); 584-587 (2012). 5 Y. Taniyasu, M. Kasu and T. Makimoto ...emitting diodes; Nature 406 (6798); 865-868 (2000). 21 U. T. Schwarz and M. Kneissl; Nitride emitters go nonpolar; physica status solidi (RRL

  9. 对我国大多数企业应用SPC不成功的思考

    Institute of Scientific and Technical Information of China (English)

    周富林

    2009-01-01

    SPC在欧美等发达国家广泛应用,但我国大多数企业并不认同SPC的有效性,约有86.8%的企业推行是不成功的.本文分析我国应用SPC的现状,并从企业最高管理者的重视程度、对SPC的认识和使用方法等几个方面来思考成功推行和实施SPC的要点.

  10. 对我国大多数企业应用SPC不成功的思考

    Institute of Scientific and Technical Information of China (English)

    周富林

    2009-01-01

    SPC在欧美等发达国家广泛应用,但我国大多数企业并不认同SPC的有效性,约有86.8%的企业推行是不成功的。本文分析我国应用SPC的现状,并从企业最高管理者的重视程度、对SPC的认识和使用方法等几个方面来思考成功推行和实施SPC的要点。

  11. Considerations technical-economical of two methods, absorption and biological, for industrial gases desulfurization; Consideraciones tecnico-economicas de dos metodos, absorcion y biologico, para la deuslfurizacion de gases industriales

    Energy Technology Data Exchange (ETDEWEB)

    Valencia Rodriguez, R.; Santiesteban Garlobo, C.; Fernandez Santana, E.; Obaya Abreu, M. C.

    2003-07-01

    In Cuba, the hydrogen sulfide removal is done by physical-chemical methods using FeO III. In the last years was developed a biological methods that using alcohol distilleries, sewage, sugar cane and porcine wastewaters with a great efficiency. From this results the economical evaluation of both methods is done. The feasibility study using the biological methods in the hydrogen sulfide removal from biogas is done. Was obtained a reduction of investment cost of 208 813, 55 USD and 54 868, 21 of production cost. (Author) 10 refs.

  12. Data of evolutionary structure change: 1EWCA-1UUPA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available -map> GLU LYS ILE PHE PRO HIS ASN TYR GLN GLY CA ...ne> ILE CA 6.82 3.81 LYS CA 3.78 GLU CA ...64 1.00 30.03 C -map> GLU HIS THR VAL ...10.56 7.03 3.80 THR CA 6.94 3.80 HIS CA 3.79 GLU CA ...C ATOM 723 CA LEU A 93 37.868 56.400 97.716 1.00 33.46 C e-

  13. INTELLIGENT TRAFFIC-SAFETY MIRROR BY USING WIRELESS SENSOR NETWORK

    Directory of Open Access Journals (Sweden)

    Peter Danišovič

    2014-03-01

    Full Text Available This article is focused on the problematic of traffic safety, dealing with the problem of car intersections with blocked view crossing by a special wireless sensor network (WSN proposed for the traffic monitoring, concretely for vehicle’s detection at places, where it is necessary. Some ultra-low-power TI products were developed due to this reason: microcontroller MSP430F2232, 868MHz RF transceiver CC1101 and LDO voltage regulator TPS7033. The WSN consist of four network nodes supplied with the special safety lightings which serve the function of intelligent traffic safety mirror.

  14. ADHD as risk factor for early onset and heightened adult problem severity of illicit substance use: An Accelerated Gateway Model

    OpenAIRE

    Dunne, Eugene M.; Hearn, Lauren E.; Rose, Jonathan; Latimer, William W.

    2014-01-01

    The primary aims of the present study were to assess ADHD history as a risk factor for earlier initiation and current use of licit and illicit substances among a sample of drug using adults. It was hypothesized that ADHD history would accelerate the Gateway Theory of drug use. Participants included 941 drug-using African American and Caucasian individuals in Baltimore, Maryland. The sample consisted of 124 (13.2%) participants who reported a history of ADHD and 817 (86.8%) who reported no his...

  15. Impact of socio demographic factors on the severity of maternal anaemia

    Directory of Open Access Journals (Sweden)

    Ambarisha Bhandiwad

    2016-03-01

    Conclusions: Anaemia in pregnancy is associated with several social and demographic factors. Strategies must be taken from the conceptional level itself by providing proper antenatal counseling and women should be economically empowered and good antenatal care must be made available and accessible to all of them. Even with routine iron prophylaxis in pregnancy, still the prevalence of anaemia is high, so should we consider one or two doses of routine parenteral iron therapy for all pregnant women? [Int J Reprod Contracept Obstet Gynecol 2016; 5(3.000: 868-872

  16. Pacific Northwest Storms Situation Report # 6

    Energy Technology Data Exchange (ETDEWEB)

    None

    2006-12-20

    Significant progress has been made in restoring power to customers in the Pacific Northwest region. Currently, 134,868 customers remain without power. The number of outages is down from 1.8 million customers who lost power following severe wind and snow storms on December 14-15, 2006. The customers without power represent less than 5 percent of customers in the affected utility service areas of Oregon and Washington. The majority of customers without power are served by Puget Sound Energy and Seattle City Light.

  17. Serum Profiling Using Protein Microarrays to Identify Disease Related Antigens

    OpenAIRE

    2014-01-01

    Disease related antigens are of great importance in the clinic. They are used as markers to screen patients for various forms of cancer, to monitor response to therapy, or to serve as therapeutic targets (Chapman et al., Ann Oncol 18(5):868–873, 2007; Soussi et al., Cancer Res 60:1777–1788, 2000; Anderson and LaBaer, J Proteome Res 4:1123–1133, 2005; Levenson, Biochim Biophy Acta 1770:847–856, 2007). In cancer endogenous levels of protein expression may be disrupted or proteins may be express...

  18. Carbon coated face-centered cubic Ru-C nanoalloys.

    Science.gov (United States)

    Zhao, Zhisheng; Meng, Chuanmin; Li, Peifang; Zhu, Wenjun; Wang, Qianqian; Ma, Yanming; Shen, Guoyin; Bai, Ligang; He, Hongliang; He, Duanwei; Yu, Dongli; He, Julong; Xu, Bo; Tian, Yongjun

    2014-09-07

    Carbon-encapsulated ruthenium-carbon (Ru-C) nanoalloys were synthesized by dynamic shocks. The Ru-C alloy shows a new fcc structure different from the original hcp structure of metal Ru. This fcc phase is assigned to a Ru32C4 solid solution with a lattice parameter of 3.868(2) Å and a bulk modulus KT0 of 272(12) GPa. The small amount of carbon in the solid solution enhances the thermodynamic and chemical stabilities with respect to pure Ru, as well as induces changes in the electronic properties, which have direct applications in improving the material's catalytic activity and selectivity.

  19. Experimental study of discharging PCM ceiling panels through nocturnal radiative cooling

    DEFF Research Database (Denmark)

    Bourdakis, Eleftherios; Péan, Thibault Q.; Gennari, Luca

    2016-01-01

    PhotoVoltaic/Thermal (PV/T) panels were used for cooling water through the principle of nocturnal radiative cooling. This water was utilised for discharging Phase Change Material (PCM) which was embedded in ceiling panels in a climate chamber. Three different sets of flow rates were examined....... The percentage of electrical energy use that could be covered from the PV/Ts on site was 71.5% for Case 1, 68.3% for Case 2 and 86.8% for Case 3. In any case, the PV/T panels proved to be an efficient solution for the production of electrical energy, heated and chilled water....

  20. Confinement effect in a quantum well dot induced by an InP stressor

    Science.gov (United States)

    Tulkki, J.; Heinämäki, A.

    1995-09-01

    We have calculated the confinement effect in an In1-xGaxAs/GaAs quantum well dot induced by a dislocation-free InP stressor island. The energy levels were calculated by including the strain interaction and the band-edge confinement in the Luttinger-Kohn Hamiltonian. The maximum level spacing for the dipole-allowed interband E1-->HH1 line spectrum was 20 meV. Our calculation also gives excellent agreement with recent measurements [H. Lipsanen, M. Sopanen, and J. Ahopelto, Phys. Rev. B 51, 13 868 (1995)] and provides indirect evidence of screened Coulomb interaction, tentatively addressed to slow carrier relaxation.

  1. Effect of darapladib on major coronary events after an acute coronary syndrome

    DEFF Research Database (Denmark)

    O'Donoghue, Michelle L; Braunwald, Eugene; White, Harvey D

    2014-01-01

    IMPORTANCE: Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been hypothesized to be involved in atherogenesis through pathways related to inflammation. Darapladib is an oral, selective inhibitor of the Lp-PLA2 enzyme. OBJECTIVE: To evaluate the efficacy and safety of darapladib in patients......]) at 868 sites in 36 countries. INTERVENTIONS: Patients were randomized to either once-daily darapladib (160 mg) or placebo on a background of guideline-recommended therapy. Patients were followed up for a median of 2.5 years between December 7, 2009, and December 6, 2013. MAIN OUTCOMES AND MEASURES...

  2. Estimating the cost of new drug development: is it really 802 million dollars?

    Science.gov (United States)

    Adams, Christopher P; Brantner, Van V

    2006-01-01

    This paper replicates the drug development cost estimates of Joseph DiMasi and colleagues ("The Price of Innovation"), using their published cost estimates along with information on success rates and durations from a publicly available data set. For drugs entering human clinical trials for the first time between 1989 and 2002, the paper estimated the cost per new drug to be 868 million dollars. However, our estimates vary from around 500 million dollars to more than 2,000 million dollars, depending on the therapy or the developing firm.

  3. Hydrolysis of lipids in chub mackerel surimi using alkaline lipase%碱性脂肪酶酶解鲐碎肉脂肪的研究

    Institute of Scientific and Technical Information of China (English)

    吴汉民; 沈莲清; 桑卫国; 董明敏; 黄晓春; 黄光荣

    2001-01-01

    采用扩展青霉(Penicillium expansum)PF868产生的碱性脂肪酶为酶源,酶解脱脂鲐碎肉,其最适条件为:32~34℃,pH 9.3,酶活浓度40 u/ml,碎肉的质量与酶液体积比为1g:5ml,脱脂时间50min.鲐碎肉的干基残脂率低于4.0%.

  4. AFOSR(Air Force Office of Scientific Research) Chemical and Atmospheric Sciences Program Review (33rd) FY88

    Science.gov (United States)

    1990-07-01

    Kramer Mel LeVan Arnaud Pagola Spencer Pugh PUBLICATIONS: "Theory of Ostwald Ripening for Open Systems", C.W. Beenakker and John Ross, J. Chem, PbIs., _I...of Periodic Perturbations on the Oscillatory Combustion of Acetaldehyde ", Spencer A. Pugh, Mark Schell, and John Ross, J. Chem. Phys., 85, 868 (1986...34Effects of Two Periodic Perturbations on the Oscillatory Combustion of Acetaldehyde ", Spencer A. Pugh, Bruce DeKock, and John Ross, J. Chem, Phys

  5. Attentional Bias to Food Cues in Youth with Loss of Control Eating

    Science.gov (United States)

    2016-05-20

    graduate school. Lastly, I would like to thank my family, who taught me the importance of education and who has unconditionally supported me...youth (14.5±2.3y; 86.8% female; BMI-z 1.7±0.73) with (n=47) and without (n=29) reported LOC eating. Following a breakfast to reduce hunger, youth... important to understand factors promoting excess body weight within obesity-prone phenotypes. ATTENTIONAL BIAS TO FOOD CUES AND OBESITY One factor

  6. 均匀设计法在POE/POE-g-MAH增韧PA6研究中的应用%Application of Homogeneous Design in the Investigation of POE/POE-g-MAH Toughened PA6

    Institute of Scientific and Technical Information of China (English)

    陈坤; 郑梯和; 曹喆

    2010-01-01

    运用均匀设计实验方法研究了聚烯烃弹性体/聚烯烃弹性体接枝马来酸酐(POE/POE-g-MAH)对聚酰胺6(PA6)的增韧作用.回归分析结果表明,当POE-g-MAH含量为7%(质量分数,下同),POE含量为18%时,PA6/POE/POE-g-MAH复合材料的缺口冲击强度达到86.8 kJ/m2.

  7. 针药并用治疗瑞士季节性变应性鼻炎68例临床观察%Clinical Observation on 68 Cases of Pollinosis Treated by Chinese Herbs Combined with Acupuncture and Moxibustion

    Institute of Scientific and Technical Information of China (English)

    王敏; 张学广; Alina Irene

    2008-01-01

    Objective To find out an effective therapy to treat pollinosis in Switzerland by Chinese herbs and acupuncture & moxibustion.Methods Gu Beng Tuo Min Fang and Acupuncture & moxibustion were used on 68 patients with pollinosis,and compared with clinical efficacy before and after treatment.One course was 20 times,and Continued about 3 months.Results Among the treated 68 cases,cured in 47,improved in 12,and total effective rate was 86.8%.Conclusion A combination of Chinese herbs and Acupuncture & Moxibustion has an exact therapeutic effect on pollinosis in Switzerland.%目的 观察中药结合针灸治疗瑞士季节性变应性鼻炎的临床疗效.方法 采用自拟固本脱敏方结合针刺和腹灸,治疗变应性鼻炎的瑞士患者68例,治疗20次(约3个月)后与治疗前进行比较.结果 68例患者中,经1个疗程治疗后,痊愈47例(69.1%)、好转12例(17.7%),总有效率为86.8%.结论 针药结合是治疗瑞士人花粉病的一种有效方法 .

  8. CATALYTIC SYNTHESIS OF BENZOCAINE WITH CHITOSAN SULFATE%壳聚糖硫酸盐催化合成苯佐卡因

    Institute of Scientific and Technical Information of China (English)

    尹大伟; 刘玉婷

    2011-01-01

    Benzocaine was synthesized using chitosan sulfate as catalyst.Simultaneously, the effect of some factors, such as the amount of catalysts, pH, time and reaction temperature on the yield of benzocaine were studied.The experiment results affirmed the best reaction conditions: pH= 2, the mass of chitosan sulfate was 0.8 g, reaction tiome was 4 h, refluxing temperature was 65 ℃, the yield of benzocaine was 86.8 %.Using chitosan sulfate in synthesis of benzocaine, the reaction condition was mild, nonexpendable, non-corrosive, and can be reused.%采用壳聚糖硫酸盐催化合成苯佐卡因(对氨基苯甲酸乙酯),讨论了催化剂用量、体系pH、反应时间和回流温度对酯产率的影响,确定了最佳的反应条件:体系pH=2,催化剂用量0.8 g (对氨基苯甲酸0.01 mol),反应时间4 h,回流温度65 ℃,苯佐卡因产率为86.8%.壳聚糖硫酸盐具有良好的催化性能,反应条件温和,无废酸产生,无腐蚀,而且可以重复使用.

  9. The optimization design of mix proportion of light heterogeneous soil mixed with expanded polystyrene%聚苯乙烯轻质混合土配合比优化设计

    Institute of Scientific and Technical Information of China (English)

    付小建; 何明胜; 眭小龙; 夏多田

    2011-01-01

    Based on orthogonal experiment, carrying on an optimization design of mix proportion of light heterogeneous soil mixed with expanded polystyrene, to explore the effects of EPS grains, cement and water on the volume density and compressive strength. The results show that when the EPS grains is 1%, cement content is 40% and contain water is 35%, the mix proportion of light heterogeneous soil mixed with expanded polystyrene is the best. At this time, the density is 1044 kg/m3, compressive strength is 2.868 Mpa, meeting requirement of compound block.%通过正交试验对聚苯乙烯轻质混合土配合比进行了优化设计,探讨了EPS颗粒、水泥、水等参数对其密度和抗压强度的影响规律.结果表明,聚苯乙烯轻质混合土的最佳配合比为EPS颗粒用量1%、水泥用量40%、含水率35%,此时密度为1044 kg/m3,抗压强度为2.868 MPa,满足复合砌块芯材的要求.

  10. Estimation and prediction of the epidemic situation of acquired immunodeficiency syndrome in Jiangsu province%江苏省AIDS疫情估计和预测分析研究

    Institute of Scientific and Technical Information of China (English)

    雷娜; 彭志行; 还锡萍; 陈鑫; 喻荣彬; 羊海涛

    2010-01-01

    Objective The aim of this study was to estimate and predict the AIDS epidemic situation in Jiangsu province by using a software named Estimation and Projection Package (EPP) and then to provide accurate information for making control plans and conducting interventions. Methods Date were obtained from the comprehensively monitored sentinels of AIDS and venereal diseases ( Data were from 28 national monitored stations and 52 provincial stations. From 2003 to 2009, a total of 10 730 000 people had been monitored) as well as project survey and laboratory tests. EPP epidemic model was employed to analyze the prevalence and to predict future epidemic situations. Results A total of 830 000 and 1 020 000 people were monitored in 2003 and 2004 respectively, and 8 880 000 more people were monitored in the following 5 years. By the end of 2009,a total of 4103 HIV infection cases had been reported,among which 918 people were diagnosed with AIDS and 432 died. Since 2003, the cases infected through IDU had decreased from 66.84% (262/392) to 16. 40% (142/868). However,the cases infected through sex contact had increased from 21.68% ( 85/392 ) to 77. 40% ( 672/868 ) . Among these cases, homosexual transmission and heterosexual transmission accounted for 39. 10% (339/868) and 38. 30% (333/868) respectively. It was estimated that there would be 14 290 HIV/AIDS cases in 2011 which is 18. 10% (2191/12 099) higher than that in 2009. The estimated HIV infection rate would be 0.02%. Conclusion EPP prediction showed the AIDS epidemic situation in Jiangsu province had an ascendant trend and the AIDS epidemic situation had demonstrated rapid growth. Therefore, it is necessary to take effective preventive measures to control the spread of AIDS.%目的 利用估计和预测软件包(estimation and projection package,EPP)模型估计和预测江苏省AIDS疫情,为制定防治规划和进行干预活动提供准确的信息.方法 分析江苏全省各类重点人群AIDS

  11. Rheological Properties of Hydrophobically Associating Polyacrylamide Solution

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A temperature-resistant, salt-tolerant polyacrylamide, hydrophobically associating polymer (HAP), was synthesized in the State Key Laboratory of Heavy Oil Processing. The rheological behavior of HAP solution was investigated by means of flow experiments in porous media and by using a HAAKE RS600 rheometer. The results of Nuclepore membrane filtration showed that filtration time increased sharply when the critical association concentration was reached. Shear rate had a greater impact on viscosity and shear stress with increasing HAP concentration. The HAP solution with a concentration of 100 mg/L (salinity 32,868 mg/L) exhibited negative thixotropy. However, at the same salinity the HAP solution showed thixotropy and its viscosity became greater when the polymer concentration increased to 1,500 mg/L.The flow experiments in cemented core samples indicated that the resistance factor and residual resistance factor of the HAP solution were 31.8 and 12 when polymer concentration and salinity were 1,500 mg/L, 32,868 mg/L at 85℃ respectively,which is favorable for flooding application. Such factors of partially hydrolyzed polyacrylamide 3530S were merely 3.14 and 1.71, so it could not be applied to polymer flooding in the oilfield with high temperature and high salinity.

  12. Natural-pose hand detection in low-resolution images

    Directory of Open Access Journals (Sweden)

    Nyan Bo Bo1

    2009-07-01

    Full Text Available Robust real-time hand detection and tracking in video sequences would enable many applications in areas as diverse ashuman-computer interaction, robotics, security and surveillance, and sign language-based systems. In this paper, we introducea new approach for detecting human hands that works on single, cluttered, low-resolution images. Our prototype system, whichis primarily intended for security applications in which the images are noisy and low-resolution, is able to detect hands as smallas 2424 pixels in cluttered scenes. The system uses grayscale appearance information to classify image sub-windows as eithercontaining or not containing a human hand very rapidly at the cost of a high false positive rate. To improve on the false positiverate of the main classifier without affecting its detection rate, we introduce a post-processor system that utilizes the geometricproperties of skin color blobs. When we test our detector on a test image set containing 106 hands, 92 of those hands aredetected (86.8% detection rate, with an average false positive rate of 1.19 false positive detections per image. The rapiddetection speed, the high detection rate of 86.8%, and the low false positive rate together ensure that our system is useable asthe main detector in a diverse variety of applications requiring robust hand detection and tracking in low-resolution, clutteredscenes.

  13. Selections from 2015: EGSY8p7, the Galaxy Far, Far Away

    Science.gov (United States)

    Kohler, Susanna

    2015-12-01

    Editors Note:In these last two weeks of 2015, well be looking at a few selections from among the most-downloaded paperspublished in AAS journals this year. The usual posting schedule will resume after the AAS winter meeting.Ly Emission from a Luminous z = 8.68 Galaxy: Implications for Galaxies as Tracers of Cosmic ReionizationPublished August 2015Main takeaway:A team led by Adi Zitrin (Hubble Fellow at California Institute of Technology) detected Ly emission in the bright galaxy EGSY8p7 using the MOSFIRE spectrograph at Keck Observatory. From this emission line, they calculated that the galaxy has an astonishing redshift of z=8.68.Why its interesting:This spectroscopic confirmation crowned EGSY8p7 as the record-holder for the farthest-known (and therefore oldest) galaxy. Its redshift shattered the previous record, a galaxy at z=7.73.Why its even more interesting than that:Spectroscopic detection of emission in EGSY8p7 with MOSFIRE. The black line is the raw data; the red line shows the best-fit model to the data. [Zitrin et al. 2015]Based on our understanding of how the universe evolved, the detection of Ly emission from this galaxy came as a surprise. At EGSY8p7s redshift of 8.68, the universe was still full of clouds of neutral hydrogen that should have absorbed the galaxys Ly emission long before it reached us. So what does it mean that we do see Ly emission from EGSY8p7? The reionization of the universe through which the neutral hydrogen clouds were made transparent may have been a patchy process. In particular, EGSY8p7 might have emitted an unusual amount of ionizing radiation, creating an early ionized bubble around it that allowed the Ly emission to escape.CitationAdi Zitrin et al 2015 ApJ 810 L12. doi:10.1088/2041-8205/810/1/L12

  14. Estrategias de aprendizaje y hábitos de estudio en el nivel superior: Diferencias según el año de cursado

    Directory of Open Access Journals (Sweden)

    Nancy Malander

    2014-05-01

    Full Text Available This research is meant to identify if the learning strategies and study habits of Higher Education students vary according to the year of study; and to detect the strategies that are used deficiently by students, mainly by first year students. The Learning and Study Strategies Inventory (LASSI was administered to 115 Higher Education students (ME age= 21.76; SD= 3.868. Statistically significant differences were found in the following LASSI scales: Motivation, Time Management, Concentration, Information Processing, Test Strategies, Attitude and Selecting Main Ideas. First year students obtained the lowest averages in every scale. The scales they put to use the least were: Time Management, Concentration, Anxiety, and Self-Testing or Control.

  15. Teacher-child interactions in Chile and their associations with prekindergarten outcomes.

    Science.gov (United States)

    Leyva, Diana; Weiland, Christina; Barata, M; Yoshikawa, Hirokazu; Snow, Catherine; Treviño, Ernesto; Rolla, Andrea

    2015-01-01

    Quality of teacher-child interactions is central to prekindergarten children's learning. In the United States, the quality of teacher-child interactions is commonly assessed using the teaching through interactions conceptual framework and an associ/ated observational tool, the Classroom Assessment Scoring System (CLASS). This study examined: (a) whether there was evidence supporting three distinctive domains of teacher-child interactions in Chile (construct validity) and (b) whether these domains predicted end-of-prekindergarten language, academic, and executive function skills in Chile (predictive validity). The sample consisted of 91 Chilean prekindergarten classrooms (1,868 four-year-old children). The findings support both construct and predictive validity of the teaching through interactions conceptual framework as assessed by the CLASS in Chile. Implications for cross-country comparison of quality of teacher-child interactions in prekindergarten classrooms are discussed.

  16. TREATMENT AND COMPREHENSIVE UTILIZATION OF SACCHARIN WASTEWATER FROM PHTHALIC ANHYDRIDE PROCESS%苯酐法糖精废水的治理与综合利用

    Institute of Scientific and Technical Information of China (English)

    崔玉民

    2005-01-01

    利用废铁屑与含铜酸性废水作用制备金属铜和聚合硫酸铁,并用聚合硫酸铁作絮凝剂处理酯化废水.实验结果表明,每吨含铜酸性废水可制得8.5kg铜粉及230kg浓度158~160 g/L Fe3+的聚合硫酸铁,处理后的酸性废水中硫酸的含量降低了83.5%,Cu2+的含量降低了85.0%;在优化条件下,沉降30min,酯化废水的COD、色度去除率分别达到86.8%、88.5%.

  17. Determination of potato glycoalkaloids using high-pressure liquid chromatography-electrospray ionisation/mass spectrometry.

    Science.gov (United States)

    Matsuda, Fumio; Morino, Keiko; Miyazawa, Haruna; Miyashita, Masahiro; Miyagawa, Hisashi

    2004-01-01

    A method for quantifying two toxic glycoalkaloids, alpha-solanine and alpha-chaconine, in potato (Solanum tuberosum) tuber tissue was developed using HPLC-electrospray ionisation (ESI)/MS. Potato samples were extracted with 5% aqueous acetic acid, and the extracts were subjected directly to HPLC-ESI/MS after filtration. By determining the intensities of the protonated molecules of alpha-solanine (m/z 868) and alpha-chaconine (m/z 852) using selected ion monitoring (positive ion mode), a sensitive assay was attained with detection limits of 38 and 14 ppb for the two glycoalkaloids, respectively. The high sensitivity and selectivity of MS detection effectively reduced the time of analysis thus enabling a high throughput assay of glycoalkaloids in potato tubers.

  18. Estadiaje local del carcinoma rectal: imágenes de ecografía versus resonancia magnética. Revisión sistemática de la literatura y metaanálisis.

    Science.gov (United States)

    Guenaga, Katia F; Otoch, Jose P; Artifon, Everson L A

    2016-01-01

    New surgical techniques in the treatment of rectal cancer have improved survival mainly by reducing local recurrences. A preoperative staging method is required to accurately identify tumor stage and planning the appropriate treatment. MRI and ERUS are currently being used for the local staging (T stage). In this review, the accuracy of MRI and ERUS with rigid probe was compared against the gold standard of the pathological findings in the resection specimens. Five studies met the inclusion criteria and were included in this meta-analysis. The accuracy was 91.0% to ERUS and 86.8% to MRI (p=0.27). The result has no statistical significance but with pronounced heterogeneity between the included trials as well as other published reviews. We can conclude that there is a clear need for good quality, larger scale and prospective studies.

  19. 喜疗妥软膏治疗血栓性外痔的临床观察%Clinical observation of effect of hirudoid on thrombosed external hemorrhoid

    Institute of Scientific and Technical Information of China (English)

    何嘉辉; 彭水清

    2014-01-01

    目的 观察喜疗妥用于治疗血栓性外痔的临床疗效.方法 73例患者随机分为两组,治疗组38例,采用高锰酸钾溶液坐盆+喜疗妥软膏外涂.对照组35例,采用高锰酸钾溶液坐盆+太宁软膏外涂.观察两组在治疗有效率的差异.结果 治疗组有效率为86.8%;对照组有效率为65.7%.两组差异具有统计学意义.结论 喜疗妥软膏对于血栓性外痔具有良好的疗效.

  20. Early discrimination of nasopharyngeal carcinoma based on tissue deoxyribose nucleic acid surface-enhanced Raman spectroscopy analysis

    Science.gov (United States)

    Qiu, Sufang; Li, Chao; Lin, Jinyong; Xu, Yuanji; Lu, Jun; Huang, Qingting; Zou, Changyan; Chen, Chao; Xiao, Nanyang; Lin, Duo; Chen, Rong; Pan, Jianji; Feng, Shangyuan

    2016-12-01

    Surface-enhanced Raman spectroscopy (SERS) was employed to detect deoxyribose nucleic acid (DNA) variations associated with the development of nasopharyngeal carcinoma (NPC). Significant SERS spectral differences between the DNA extracted from early NPC, advanced NPC, and normal nasopharyngeal tissue specimens were observed at 678, 729, 788, 1337, 1421, 1506, and 1573 cm-1, which reflects the genetic variations in NPC. Principal component analysis combined with discriminant function analysis for early NPC discrimination yielded a diagnostic accuracy of 86.8%, 92.3%, and 87.9% for early NPC, advanced NPC, and normal nasopharyngeal tissue DNA, respectively. In this exploratory study, we demonstrated the potential of SERS for early detection of NPC based on the DNA molecular study of biopsy tissues.

  1. A Five Month Old Girl with Deletion in 5th Chromosome: Cri du Chat Syndrome

    Directory of Open Access Journals (Sweden)

    Tolga Altuğ Şen

    2008-10-01

    Full Text Available This five month-old girl was admitted to our clinic due to failure to thrive. On physical examination, her weight, length and head circumference was below the 3rd percentile, she had blond hair, facial dysmorphism and high arched palate. Pronounced hypotonia and motor retardation was present and high-pitched crying was striking. In echocardiographic examination, secundum type ASD and midtrabecular VSD without any important hemodynamic effect was present. In cranial MRI exmination, dilated 4th ventricles and delayed myelinisation in basal ganglia was detected. By the help of high resolution binding teqhnique, deletion in the short arm of the 5th chromosome was detected and diagnosis of Cri du Chat Syndrome was made. (Journal of Current Pediatrics 2008; 6: 86-8

  2. Automated Gun Laying System for Self-Propelled Artillery Weapons.

    Science.gov (United States)

    1980-05-30

    since it is not synchronous with the XENON channel. The time gates established by the phase locked loop eliminate approximately 80% of any spurious...MB 3 02940 0070 0002 FIOLDX RUB 20 242c 0021 OMul DISEL R4B 102950 0072 0002 TIZX RUB 2,2430 , G2C 0001 DISAL RUB 1 02960 0074 0002 STORX RUB 2_2440 2...A039 J41lO * READ AZ AND EL GACS 04710 4101 7E 4023 imp A,2 0’"’) 4099 7F 0028 CLR DISEL 0410 41SET 0U JLAG0: 1 409C 868 D 5VN04720 ’*SET RU FLAGS

  3. Metrics for Emitter Selection for Multistatic Synthetic Aperture Radar

    Science.gov (United States)

    2013-09-01

    9,11,19,22 867 7,9,14,19 13,18,20,22 15,16,22 8,18,20,22 929 14,16,20 14,18,20 8,11,13,20 9,18,20 868 10,14,19,20 8,12,17,19 9,12,22 8,16,20,22 930...8,10,17,19 1011 7,19,20 14,19,20 8,11,12,20 9,10,20,22 1073 14,17,19,20 10,12,19 10,17,20 11,16,19,22 1012 16,18,19,20 13,14,16,19 11,13,20,22 10,12,16,22

  4. LONG-TERM EFFECT OF HOMOHARRINGTONINE ON CHRONIC GRANULOCYTIC LEUKEMIA

    Institute of Scientific and Technical Information of China (English)

    LI Yu-feng; ZHU Jia-bin; WANG Chun-ling; DING Bang-he; LI Yuan-yuan; XUAN Heng-bao; QIAN Mo-sheng

    2005-01-01

    Objective: To observe the long-term effect of homoharringtonine (HHT) on chronic granulocytic leukemia (CGL) and its pharmacological mechanism. Methods: 76 patients with newly diagnosed early chronic phase CGL received treatment of merely 1.5 mg/m2 daily HHT for induction remission and long-term maintenance treatment. The apoptosis rate of bone marrow CD34+ cells induced by HHT was assayed with flow cytometer. Results: 86.8% patients achieved CHR, 13.2% patients PHR and 31.8% patients got cytogenetic response in HHT treatment group, which was longer than 31 (8-54) months in hydroxyurea (HU) group (P<0.05). The effect of apoptosis induction HHT was stronger on CGL-CP patients bone marrow CD34+ cells than on normal person bone marrow CD34+ cells. Conclusion: HHT is a very effective drug for remission induction and long-term maintenance treatment in early chronic phase CGL patients.

  5. Thermal evaporation-induced anhydrous synthesis of Fe3O4-graphene composite with enhanced rate performance and cyclic stability for lithium ion batteries.

    Science.gov (United States)

    Dong, Yucheng; Ma, Ruguang; Hu, Mingjun; Cheng, Hua; Yang, Qingdan; Li, Yang Yang; Zapien, Juan Antonio

    2013-05-21

    We present a high-yield and low cost thermal evaporation-induced anhydrous strategy to prepare hybrid materials of Fe3O4 nanoparticles and graphene as an advanced anode for high-performance lithium ion batteries. The ~10-20 nm Fe3O4 nanoparticles are densely anchored on conducting graphene sheets and act as spacers to keep the adjacent sheets separated. The Fe3O4-graphene composite displays a superior battery performance with high retained capacity of 868 mA h g(-1) up to 100 cycles at a current density of 200 mA g(-1), and 539 mA h g(-1) up to 200 cycles when cycling at 1000 mA g(-1), high Coulombic efficiency (above 99% after 200 cycles), good rate capability, and excellent cyclic stability. The simple approach offers a promising route to prepare anode materials for practical fabrication of lithium ion batteries.

  6. Clinical Research on Treatment of Hyperkinetic Syndrome of Childhood by Electroacupuncture plus Acupoint Application

    Institute of Scientific and Technical Information of China (English)

    WU Yao-chi; KUAI Le

    2003-01-01

    Objective To observe the clinical therapeu tic effect of hyperkinetic syndrome of childhood treated by electroacupuncture plus acupoint application. Method Sixty-five cases with hyperkinetic syndrome of childhood were treated by electroacupuncture plus acupoint application (electroacupuncture group); 53 cases were treated by acupuncture (acupuncture group) and 53 cases were treated by Ritalin (west drug group). The above three groups were compared with each other in therapeutic effect. Results The effective rate of treating hyperkinetic syndrome of childhood by electroacupuncture plus acupoint application was 87.7%; the effective rate in west drug group was 86.8% and in acupuncture group was 77.4%. A comparison among the three groups showed there was no significant difference in clinical ther apeutic effect ( P > 0.05 ). Conclusion Electroacupuncture plus acupoint application was an effective therapy of hyperkinetic syndrome of childhood.

  7. 3D-QSAR Investigation of Synthetic Antioxidant Chromone Derivatives by Molecular Field Analysis

    Directory of Open Access Journals (Sweden)

    Jiraporn Ungwitayatorn

    2008-02-01

    Full Text Available A series of 7-hydroxy, 8-hydroxy and 7,8-dihydroxy synthetic chromone derivatives was evaluated for their DPPH free radical scavenging activities. A training set of 30 synthetic chromone derivatives was subject to three-dimensional quantitative structure-activity relationship (3D-QSAR studies using molecular field analysis (MFA. The substitutional requirements for favorable antioxidant activity were investigated and a predictive model that could be used for the design of novel antioxidants was derived. Regression analysis was carried out using genetic partial least squares (G/PLS method. A highly predictive and statistically significant model was generated. The predictive ability of the developed model was assessed using a test set of 5 compounds (r2pred = 0.924. The analyzed MFA model demonstrated a good fit, having r2 value of 0.868 and crossvalidated coefficient r2cv value of 0.771.

  8. The Clinical Study of Telomerase Activity in Gastric Tumor

    Institute of Scientific and Technical Information of China (English)

    XI Weihong; NI Xiaoqian; SHEN Yuqin; HUANG Qinmei

    2002-01-01

    Telomerase activity was detected with both telomeric repeat amplification protocol (TRAP) - silver stain and polymerase chain reaction (PCR) - enzyme linked immuno - sorbent assay (ELISA). We have studied the telomerase activity in the 68 gastric tumors and their neighboring tissues,25 gastric ulcer, and 3 tumor cell colonies. The positive rate of telomerase activity in gastric tumors was 86.8% (59/68) and which was obviously higher than 7.3% (5/68) in the normal tissues adjacent to the tumors and 4% (1/25) in gastric ulcer. The telomerase activity was 100% (3/3) in the tumor colonies. It allowed to be seen that higher telomerase activity was associated with the origin and development of the gastric tumor. We believe that telomerase activity may be a useful clinical diagnostic marker for the gastric tumor.

  9. 甘薯的主要营养成分和保健作用%Main Nutritional Components of Ipomoea Batatas and Its Healthy Functions

    Institute of Scientific and Technical Information of China (English)

    张立明; 王庆美; 王荫墀

    2003-01-01

    @@ 甘薯(Ipomoea batatas)是世界上重要的粮食、饲料和工业原料作物,普遍种植于世界上热带和亚热带地区的100多个国家.甘薯自400多年前引入中国,目前我国已成为世界上最大的甘薯生产国,据FAO(2000年)统计,我国甘薯年种植面积616万hm2,总产11.7亿t,分别占世界种植面积和总产的68.1%和86.8%.

  10. Synthesis of fatty acid methyl ester from crude jatropha (Jatropha curcas Linnaeus) oil using aluminium oxide modified Mg-Zn heterogeneous catalyst.

    Science.gov (United States)

    Olutoye, M A; Hameed, B H

    2011-06-01

    The synthesis of fatty acid methyl esters (FAME) as a substitute to petroleum diesel was investigated in this study from crude jatropha oil (CJO), a non-edible, low-cost alternative feedstock, using aluminium modified heterogeneous basic oxide (Mg-Zn) catalyst. The transesterification reaction with methanol to methyl esters yielded 94% in 6h with methanol-oil ratio of 11:1, catalyst loading of 8.68 wt.% at 182°C and the properties of CJO fuel produced were determine and found to be comparable to the standards according to ASTM. In the range of experimental parameters investigated, it showed that the catalyst is selective to production of methyl esters from oil with high free fatty acid (FFA) and water content of 7.23% and 3.28%, respectively in a single stage process. Thus, jatropha oil is a promising feedstock for methyl ester production and large scale cultivation will help to reduce the product cost.

  11. Determination of trace phenol in water by microwave-assisted extraction and gas chromatography%水中痕量苯酚的微波萃取气相色谱分析

    Institute of Scientific and Technical Information of China (English)

    谭晓燕; 黎国兰; 李松; 赵莹

    2009-01-01

    A method of microwave-assisted extraction and gas chromatography for determination of trace phenol in water was established.The conditions of microwave extraction and derivation were optimized.Acetone-cyclohexane phenol and acetic anhydride was employed for the direct acetylation of phenol.Petroleum ether was used as the extracting agent to extract the derivative of phenol.Detection was carried out in GC - FID equipped with DB-17 (30 m×0.53 mm×1.0 μm) capillary column.The detection limit of the proposed method was found to be 0.01μg.L-1.Recoveries were in the range of 86.8%~99.2% with RSD of 4.2%.This method has proved to be high sensitive,efficient and accurate.

  12. A study of electrode wear ratio on EDM of Ti-6AL-4V with copper-tungsten electrode

    Directory of Open Access Journals (Sweden)

    Zainal Nurezayana

    2016-01-01

    Full Text Available In this work, a study of electrode wear ratio (EWR on the diesinking electrical discharge machining (EDM of Ti-6AL-4V titanium alloy with copper-tungsten (Cu-W electrode has been carried out. Pulse on time (ON, pulse of time (OFF, peak current (V and servo voltage (SV were seen as the machining parameters. The experiments were run according to the design of experiments (DOE, which is two levels of full factorial with added centre points. The experimental results reveal that pulse on time and peak current are statistically significant parameters for affecting EWR with the p-value of 0.0013 and 0.0012 respectively. Moreover, based on ANOVA, we recognized peak current as the most significant parameters which contribute 31.75%, followed by pulse on time, servo voltage and pulse on time which contribute 30.99%, 8.68% and 0.72%, respectively.

  13. Iron bromide vapor laser

    Science.gov (United States)

    Sukhanov, V. B.; Shiyanov, D. V.; Trigub, M. V.; Dimaki, V. A.; Evtushenko, G. S.

    2016-03-01

    We have studied the characteristics of a pulsed gas-discharge laser on iron bromide vapor generating radiation with a wavelength of 452.9 nm at a pulse repetition frequency (PRF) of 5-30 kHz. The maximum output power amounted to 10 mW at a PRF within 5-15 kHz for a voltage of 20-25 kV applied to electrodes of the discharge tube. Addition of HBr to the medium produced leveling of the radial profile of emission. Initial weak lasing at a wavelength of 868.9 nm was observed for the first time, which ceased with buildup of the main 452.9-nm line.

  14. Molecular cloning and sequence analysis of salt-resistant gene in Artemia%盐生卤虫BADH基因的克隆及序列分析

    Institute of Scientific and Technical Information of China (English)

    赵秀娟; 孙晓娟; 蔡禄

    2009-01-01

    实验以盐生动物卤虫(Artemia)为材料,采用酚-氯仿法提取总DNA,以已报道的BADH基因的保守序列设计引物,通过PCR技术,从卤虫的基因组DNA中分离得到了1个BADH基因片段,经测序,得到一段868 bp的核苷酸序列,输入CenBank进行BLAST同源性比较,发现所得片段与植物中的籽粒苋的BADH4基因中的一段序列有96%的同源性,此项研究为更深入地研究抗盐动物的BADH基因奠定了良好的基础.

  15. A systematic search for the spectra with features of crystalline silicates in the Spitzer IRS Enhanced Products

    CERN Document Server

    Chen, Rui; Liu, Jiaming; Jiang, Biwei

    2016-01-01

    The crystalline silicates features are mainly reflected in infrared bands. The Spitzer Infrared Spectrograph (IRS) collected numerous spectra of various objects and provided a big database to investigate crystalline silicates in a wide range of astronomical environments. We apply the manifold ranking algorithm to perform a systematic search for the spectra with crystalline silicates features in the Spitzer IRS Enhanced Products available. In total, 868 spectra of 790 sources are found to show the features of crystalline silicate. These objects are cross-matched with the SIMBAD database as well as with the Large Sky Area Multi-Object Fibre Spectroscopic Telescope (LAMOST)/DR2. The average spectrum of young stellar objects show a variety of features dominated either by forsterite or enstatite or neither, while the average spectrum of evolved objects consistently present dominant features of forsterite in AGB, OH/IR, post-AGB and planetary nebulae. They are identified optically as early-type stars, evolved stars...

  16. Elevated serotonin transporter binding in depressed patients with Parkinson's disease: a preliminary PET study with [11C]DASB.

    Science.gov (United States)

    Boileau, Isabelle; Warsh, Jerry J; Guttman, Mark; Saint-Cyr, Jean A; McCluskey, Tina; Rusjan, Pablo; Houle, Sylvain; Wilson, Alan A; Meyer, Jeffrey H; Kish, Stephen J

    2008-09-15

    This study investigated whether abnormalities in serotonin transporter binding occur in Parkinson's disease (PD) patients with concurrent depression. We estimated serotonin transporter levels in seven clinically depressed early-stage PD patients and in seven healthy matched-control subjects during a single positron emission tomography (PET) scan with the serotonin transporter radioligand, [(11)C]DASB. Depressed PD patients displayed a wide-spread increase (8-68%) in [(11)C]DASB specific binding outside of the striatum, which was significant in dorsolateral (37%) and prefrontal (68%) cortices. Elevated [(11)C]DASB binding was positively correlated with depressive symptoms but not with disease severity or duration. Compatible with recent PET/[(11)C]DASB findings in major depression, the present preliminary data suggest that increased [(11)C]DASB binding, possibly reflecting greater serotonin transporter density (up-regulation), might be a pathological feature of depression in Parkinson's disease-and possibly a characteristic of depressive illness in general.

  17. Clinical manifestations of patients with chikungunya fever at different age groups%不同年龄组基孔肯雅热患者的临床表现比较

    Institute of Scientific and Technical Information of China (English)

    翟洁卿; 吴福全; 黄育波; 李鸿超; 陈桂轩; 林炳亮

    2011-01-01

    目的 分析不同年龄组基孔肯雅热患者的临床表现.方法 130例基孔肯雅热患者,按年龄分为三组:<30岁、30~岁、≥60岁组,分析其临床症状的差异.结果 三组患者均出现发热,皮疹的发生率分别为86.8%、91.4%、90.9%,关节痛的比例分别为86.8%、91.4%、95.5%,关节痛持续时间超过14d的比例分别为2.6%、30.0%、36.4%;与<30岁组比较,30~岁和≥60岁组患者出现关节痛持续时间超过14 d以及累及3个或以上关节的比例高,差异均有统计学意义(x2= 13.026,P=0.001;x2=6.792,P=0.034).结论 基孔肯雅热主要表现为发热、皮疹、关节痛,中、老年组患者出现关节疼痛持续时间较长,累及的关节多.%Objective To analyze clinical manifestations of different age group patients with chikungunya fever. Methods According to the age, 130 patients with chikungunya fever were divided into 3 groups (Group 1: less than thirty years; Group 2: from thirty to fifty-nine years; Group 3; over sixty years). Results All the patients in three groups had fever, and 86.8% of patients in group 1, 91.4% in group 2 and 95.5% in group 3 had rash. The arthralgia rates of group 1, 2 and 3 were 86.8%, 91.4% and 95.5% respectively. And 2.6% of group 1 patients, 30.0% of group 2, and 36.4% of group 3 were persistently with arthralgia more than 14 days. The rates of having arthraglia more than 14 days and not less than 3 joints of patients in group 2 and group 3 were higher than that in group 1 (x2= 13.026, P=0.001; x2=6.792, P=0.034). Conclusion The main symptoms of chikungunya fever were fever, rash and arthralgia. Older patients had a longer time of rathralgia and more joints injured.

  18. Analysis of Genetic Specificity and DNA Fingerprinting Establishment for the Hainan Island Landraces of Cucurbita moschata%中国南瓜海南农家品种间的遗传特异性分析和DNA指纹图谱构建

    Institute of Scientific and Technical Information of China (English)

    云天海; 郑道君; 谢良商; 邓长智

    2013-01-01

    Based on the collection of Hainan island landraces of Cucurbita moschata,the present study was aimed to analyze their genetic specificity and establish DNA fingerprinting for 28 landraces by inter-simple sequence repeat(ISSR) and sequence-related amplified polymorphism (SRAP),which would provide applicable guidance for identification,evaluation,protection,and utilization of Hainan island landraces of C.moschata.The results showed that genetic specificity was significant among the 28 landraces with special genetic background,1O specific markers and 11 unique-lack bands scored were produced by 6 ISSR primers and 11 SRAP primer pairs.And four DNA fingerprintings for the 28 landraces were developed by two ISSR primer combinations and two SRAP primer combinations,i.e.UBC807/UBC814/UBC844/UBC868,UBC808/UBC814/UBC844/UBC868,Me1/Em2 + Me1/Em10 +Me2/Em3,Me1/Em1 + Me1/Em10 + Me8/Em3,respectively.All the DNA fingerprintings developed were intuitionistic and simple.ISSR and SRAP molecular markers could be effectively used in the analysis of genetic specificity and DNA fingerprinting establishment for the landraces of C.moschata.%在收集中国南瓜海南农家品种的基础上,应用ISSR和SRAP标记技术对28份海南农家品种间的遗传特异性进行了分析,并构建指纹图谱,为中国南瓜海南农家品种鉴定、评价、保护和利用提供科学依据.结果表明,所供试的品种间存在显著的遗传特异性,具有特殊的遗传基础或背景,所筛选的6个ISSR引物和11对SRAP引物共产生了10个特异标记和11条唯一缺失带;应用ISSR引物组合UBC807/UBC814/UBC844/UBC868和UBC808/UBC814/UBC844/UBC868,以及SRAP引物组合Me1/Em2+ Me1/Em10+ Me2/Em3和Me1/Em1+Me1/Em10+ Me8/Em3分别绘制了4个28份中国南瓜海南农家品种的DNA指纹图谱,所构建的DNA指纹图谱直观、简单.ISSR标记和SRAP标记技术可有效应用于中国南瓜海南农家品种DNA指纹图谱的构建和遗传特异性鉴定.

  19. A novel comparative molecule/pseudo receptor interaction analysis

    Institute of Scientific and Technical Information of China (English)

    ZHOU Peng; TONG Jianbo; TIAN Feifei; LI Zhiliang

    2006-01-01

    Comparative molecule/pseudo receptor interaction analysis (CoMPIA) is developed as a novel 3D-QSAR method by adding postulated pseudo receptor and GA-optimized probe into comparative molecular field analysis (CoMFA). CoMPIA is used to find the pseudo receptor mode by optimizing probe distributions and to establish the optimal model of high qualities and good interpretations. Correlative coefficient R2, cross-validated correlative coefficient Q2 and root mean square error RMSEP of the resulting model are 0.940, 0.868 and 0.502, respectively by applying CoMPIA to quantitative structure-activity relationship (QSAR) of 31 classical steroids.

  20. A Measurement of the t $\\bar{t}$ Production Cross Section in p $\\bar{p}$ Collisions at √s = 1.96-TeV using Soft Muon Tagging

    Energy Technology Data Exchange (ETDEWEB)

    Grundler, Ulysses Allen [Univ. of Illinois, Urbana-Champaign, IL (United States)

    2008-01-01

    I present a measurement of the t$\\bar{t}$ production cross section at √s = 1.96 TeV using 2034 pb-1 of CDF Run II data using events with a high transverse momentum electron or muon, three or more jets, and missing transverse energy. The measurement assumes a t → Wb branching fraction of 100 percent. Events consistent with t$\\bar{t}$ decay are found by identifying jets containing heavy-flavor semileptonic decays to muons. The dominant backgrounds are evaluated directly from the data. Based on 248 candidate events and an expected background of 86.8 ± 5.6 events, I measure a production cross section of 8.7 ± 1.1$+0.9\\atop{-0.8}$ ± 0.6 pb, in agreement with the Standard Model.

  1. Alcohol intake and colorectal cancer: a comparison of approaches for including repeated measures of alcohol consumption

    DEFF Research Database (Denmark)

    Thygesen, Lau Caspar; Wu, Kana; Grønbaek, Morten;

    2008-01-01

    BACKGROUND: In numerous studies, alcohol intake has been found to be positively associated with colorectal cancer risk. However, the majority of studies included only one exposure measurement, which may bias the results if long-term intake is relevant.METHODS: We compared different approaches...... for including repeated measures of alcohol intake among 47,432 US men enrolled in the Health Professionals Follow-up Study. Questionnaires including questions on alcohol intake had been completed in 1986, 1990, 1994, and 1998. The outcome was incident colorectal cancer during follow-up from 1986 to 2002.RESULTS......: During follow-up, 868 members of the cohort experienced colorectal cancer. Baseline, updated, and cumulative average alcohol intakes were positively associated with colorectal cancer, with only minor differences among the approaches. These results support moderately increased risk for intake >30 g...

  2. The Impact of Learning Assistants on Inequities in Physics Student Outcomes

    CERN Document Server

    Van Dusen, Ben; Roualdes, Edward

    2016-01-01

    This study investigates how Learning Assistants (LAs) and related course features are associated with student learning inequities in introductory university physics courses. Over 2,868 physics student paired pre- and post-test scores on concept inventories from 67 classes in 16 LA Alliance member institutions were collected. The concept inventories included the Force Concept Inventory, Force and Motion Conceptual Evaluation, and the Conceptual Survey of Electricity and Magnetism. Our analyses developed a multiple linear regression model that examines the impact of student (e.g. gender and race) and course level variables (e.g. presence of LAs and Concept Inventory used) on student learning outcomes (Cohen's d effect size) across classroom contexts. The presence of LAs was found to remove or invert the traditional performance gaps between majority and underrepresented minority students. Significant differences in student performance were also found across the concept inventories.

  3. Automatic classification of pulmonary peri-fissural nodules in computed tomography using an ensemble of 2D views and a convolutional neural network out-of-the-box.

    Science.gov (United States)

    Ciompi, Francesco; de Hoop, Bartjan; van Riel, Sarah J; Chung, Kaman; Scholten, Ernst Th; Oudkerk, Matthijs; de Jong, Pim A; Prokop, Mathias; van Ginneken, Bram

    2015-12-01

    In this paper, we tackle the problem of automatic classification of pulmonary peri-fissural nodules (PFNs). The classification problem is formulated as a machine learning approach, where detected nodule candidates are classified as PFNs or non-PFNs. Supervised learning is used, where a classifier is trained to label the detected nodule. The classification of the nodule in 3D is formulated as an ensemble of classifiers trained to recognize PFNs based on 2D views of the nodule. In order to describe nodule morphology in 2D views, we use the output of a pre-trained convolutional neural network known as OverFeat. We compare our approach with a recently presented descriptor of pulmonary nodule morphology, namely Bag of Frequencies, and illustrate the advantages offered by the two strategies, achieving performance of AUC = 0.868, which is close to the one of human experts.

  4. The State of Food Security Report 2012 and the Enigma of Achieving Millennium Development Goals

    Directory of Open Access Journals (Sweden)

    Vikas Bajpai

    2013-07-01

    Full Text Available Globally quoted and unquestioningly accepted, the State of the Food Insecurity in the world report 2012, has made significant reduction in the numbers of hungry globally at 868 million. In case of India it has made significant upward revision of hunger prevalence in 1990-92 and significant downward revision for 2010 resulting in 34.9% estimated hunger decline. In the midst of claims of robust methodological revisions, its calculations and assumptions set a dangerous precedence for the policy-makers and planners of the reluctant country governments and worst for the hungry of the world. This paper discusses the SOFI 2012, critiques the declining hunger numbers in SOFI 2012 and produces alternate data sets including independent surveys of Government of India, to counter the reduction claims. It also makes a case for greater public dialogue and engagement in such reports, their methods, metrics and numbers.

  5. CLONING OF P32 GENE ENCODING THE MAJOR SURFACE PROTEIN FROM THEILERIA ORIENTALISI%牛东方泰勒虫P32主要表面蛋白基因的克隆与分析

    Institute of Scientific and Technical Information of China (English)

    杨艳玲; 张西臣; 张国才; 白光彦; 李建华

    2007-01-01

    通过PCR技术从感染吉林株东方泰勒虫的病牛血液中扩增出868 bp的表面蛋白P32基因,经测序比较分析发现与韩国株核苷酸和氨基酸的同源性分别为99%和98%.和我国延边株核苷酸和氨基酸的同源性分别为99%和98%.将所得的吉林株东方泰勒虫P32蛋白基因序列提交GenBank,基因注册号为EU047751.

  6. (R,S-2′-Amino-6′-methyl-2,5′,5′-trioxo-6′H-spiro[indoline-3,4′-pyrano[3,2-c][2,1]benzothiazine]-3′-carbonitrile dimethylformamide monosolvate

    Directory of Open Access Journals (Sweden)

    Svitlana V. Shishkina

    2014-07-01

    Full Text Available The title solvate, C20H14N4O4S·C3H7NO, comprises a stereogenic centre but the centrosymmetric space group causes the presence of the racemate in the crystal. The spiro-joined fragments are almost orthogonal, with a dihedral angle of 86.8 (2° between the mean planes of the pyrane ring and the dihydroindolone ring system. The atoms of the indolinone bicycle are coplanar, with an r.m.s. deviation of 0.005 Å. In the crystal, pairs of N—H...O hydrogen bonds link the molecules into centrosymmetric dimers which are linked to the dimethylformamide solvent molecules by further N—H...O hydrogen bonds. N—H...N hydrogen bonds link neighbouring dimers into [010] chains.

  7. K4Sn3Se8的固相合成、晶体结构和反射光谱研究%Solid state synthesis,crystal structure and diffuse reflectance spectra of K4Sn3Se8

    Institute of Scientific and Technical Information of China (English)

    王志霞; 郭洪猷

    2003-01-01

    采用反应性熔盐法,通过中温固相反应在500 ℃下合成晶体K4Sn3Se8.该晶体属正交晶系,空间群Ccca,晶胞参数:a=0.821 15(6) nm,b=2.779 0(2) nm,c=0.818 65(6) nm,V=1.868 2(2) nm3,Z=4.K4Sn3Se8由[Sn3Se8]4-三聚体负离子和K+正离子组成.漫反射光谱研究表明该材料能隙(Eg)为2.6 eV,属于半导体,对太阳能具有选择吸收的特性.

  8. Computerized Analysis of Nutrients (CAN) System

    Science.gov (United States)

    1989-11-01

    8 .8 58.8 CEREAL-CORN FLAKES K 808020 113 .7 .7 59.6 ORANGE MINUS SKIN 809203 ill .7 .7 60.3 CUCUMBER -RAW 811205 110 .7 .7 61.0 CRACKERS, SALTINES...RICE 8 9L E00503 29 .2 .2 86.8 LASAGNA 8 4D L02500 29 .2 .2 87.0 PICKLE SWEET 015610 28 .2 .2 87.2 MILK-SKIM 801085 28 .2 .2 87.4 PLUM-FRESH-9% 809279 28...L158LQ 17 .1 .1 94.7 ,MASHED POTATOES 8 1 POTATO 17 .1 .1 94.8 BEANS LIMA, CANNED QG1650 17 .1 .1 94.9 PICKLE -DILL 015580 16 .1 .1 95.0 CHEESE-COTTAGE

  9. Factors associated with offal, partial and whole carcass condemnation in ten French cattle slaughterhouses.

    Science.gov (United States)

    Dupuy, Céline; Demont, Pierre; Ducrot, Christian; Calavas, Didier; Gay, Emilie

    2014-06-01

    The proportion of cattle with offal, partial or whole carcass condemnation could be a useful indicator for animal health syndromic surveillance purposes. It requires first highlighting the factors associated with condemnation in order to include them in a modeling process. This study aims to identify and quantify these factors. It was based on data from ten French cattle slaughterhouses from 2006 to 2010 (n=1,439,868 cattle). Multivariable multinomial logistic regression analyses were performed. Sex, age and slaughterhouse were the main effects for offal, partial and whole carcass condemnation and have to be taken into account when implementing syndromic surveillance systems based on meat inspection data. The presence of an error in cattle identification was identified as a potential indicator for a higher risk of condemnation and should be explored as a potential factor for risk-based meat inspection.

  10. ISSR Analysis of Chlorophytum Treated by Three Kinds of Chemical Mutagen

    Institute of Scientific and Technical Information of China (English)

    WU Lijun; LI Muzi; YANG Xue; YANG Tao; WANG Jingang

    2011-01-01

    Chlorophytum leaves were treated with three kinds of chemical mutagen, EMS, DES and NaN3 with different concentration to obtain the variation materials with excellent properties. The results showed that the genetic similarity coefficient of variation plants with EMS treatment was between 0.648 and 0.868, with NaN3 treatment was between 0.598 and 0.859, and with DES treatment was between 0.668 and 0.904, of which the mutagenic effects with 0.8% EMS, 250 mg. L-1 NaN3 and 0.3% DES on chloro- phytum were the best. ISSR molecular marker technique was used to analyze their genetic diversities. Total 392 polymorphic bands were obtained through 18 ISSR primers. Polymorphic ratio was 72.4%, which showed that DNA mutation took place in various degrees

  11. Highly efficient betanin dye based ZnO and ZnO/Au Schottky barrier solar cell

    Energy Technology Data Exchange (ETDEWEB)

    Thankappan, Aparna, E-mail: aparna.subhash@gmail.com [International School of Photonics (ISP), Cochin University of Science and Technology, Kochi (India); Inter University Centre for Nanomaterials and Devices (IUCND), Cochin University of Science and Technology, Kochi (India); Divya, S.; Augustine, Anju K.; Girijavallaban, C.P.; Radhakrishnan, P.; Thomas, Sheenu; Nampoori, V.P.N. [International School of Photonics (ISP), Cochin University of Science and Technology, Kochi (India)

    2015-05-29

    Performance of dye sensitized solar cells based on betanin natural dye from red beets with various nanostructured photoanodes on transparent conducting glass has been investigated. In four different electrolyte systems cell efficiency of 2.99% and overall photon to current conversion efficiency of 20% were achieved using ZnO nanosheet electrode with iodide based electrolyte in acetonitrile solution. To enhance solar harvesting in organic solar cells, uniform sized metal nanoparticles (gold (Au) of ~ 8 nm) synthesized via microwave irradiation method were incorporated into the device consisting of ZnO. Enhanced power conversion efficiency of 1.71% was achieved with ZnO/Au nanocomposite compared to the 0.868% efficiency of the bare ZnO nanosheet cell with ferrocene based electrolyte. - Highlights: • The influence of electrolytes has been studied. • Cell efficiency of 2.99% was achieved by ZnO. • Enhancement of efficiency with incorporation of Au nano.

  12. Data of evolutionary structure change: 1DJ2B-1LOOA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 53.44 C ATOM 4017 CA ILE B 116 7.845 51.035 75.767 1.00 40.12 C ...ine> ARG CA 3.81 ILE CA -map> S...6.242 58.868 1.00 52.12 C ATOM 759 CA LEU A 128 58.431 50.008 58.168 1.00 44.30 C ...S CA 5.79 3.80 ARG CA 3.83 LEU CA e-map> LYS CA 212...ne>ATOM 4263 CA GLY B 146 -9.857 73.219 68.231 1.00100.00 C -map>

  13. Dicty_cDB: AFM537 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AF (Link to library) AFM537 (Link to dictyBase) - - - - AFM537P (Link to Original site) AFM537F 220 AFM...537Z 668 AFM537P 868 - - Show AFM537 Library AF (Link to library) Clone ID AFM537 (Link ...to dictyBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig - Original site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/AF/AFM...5-B/AFM537Q.Seq.d/ Representative seq. ID AFM537P (Link to ...Original site) Representative DNA sequence >AFM537 (AFM537Q) /CSM/AF/AFM5-B/AFM537Q.Seq.d/ ATTAAATTCCATCATTG

  14. Increasing socio-economic inequalities in life expectancy and QALYs in Sweden 1980-1997

    DEFF Research Database (Denmark)

    Burström, Kristina; Johannesson, Magnus; Diderichsen, Finn

    2005-01-01

    to mortality data, to estimate the life expectancy in different socio-economic groups in 1980 and 1997 (n=100 868). Health state scores were obtained by mapping responses to selected ULF survey interview questions into the generic health-related quality of life measure EQ-5D, using the UK EQ-5D index tariff (n......=34 447). For 20-year-old men the difference in life expectancy between the highest (higher non-manual) and the lowest socio-economic group (unskilled manual) was 2.11 years in 1980 and 3.79 years in 1997. The corresponding figures for 20-year-old women were 1.56 in 1980 and 2.15 in 1997...

  15. Low-Frequency MEMS Electrostatic Vibration Energy Harvester With Corona-Charged Vertical Electrets and Nonlinear Stoppers

    Science.gov (United States)

    Lu, Y.; Cottone, F.; Boisseau, S.; Galayko, D.; Marty, F.; Basset, P.

    2015-12-01

    This paper reports for the first time a MEMS electrostatic vibration energy harvester (e-VEH) with corona-charged vertical electrets on its electrodes. The bandwidth of the 1-cm2 device is extended in low and high frequencies by nonlinear elastic stoppers. With a bias voltage of 46 V (electret@21 V + DC external source@25 V) between the electrodes, the RMS power of the device reaches 0.89 μW at 33 Hz and 6.6 μW at 428 Hz. The -3dB frequency band including the hysteresis is 223∼432 Hz, the one excluding the hysteresis 88∼166 Hz. We also demonstrate the charging of a 47 μF capacitor used for powering a wireless and autonomous temperature sensor node with a data transmission beyond 10 m at 868 MHz.

  16. Use of IQRF technology for detection of construction inclination

    Science.gov (United States)

    Martin, Pies; Radovan, Hajovsky

    2016-06-01

    This paper deals with the application of wireless measurement of inclination of objects located at mining dumps. Measurement of inclination uses a set of sensors including a gyroscope, an accelerometer and a magnetometer. Measured data is processed by AHRS algorithm that, once applied, allows getting more precise information on rotation of the object in the area compared to unprocessed data from accelerometer or gyroscope. Measurement chain consists of two parts. The first one is a wireless module reading the data from particular sensors via I2C bus and sends it consequently to a computer that performs evaluation and visualization of inclination. Communication among particular devices is ensured by IQRF technology working within ISM band of 868MHz. Application of this approach for measurement of inclination is a reasonable choice in case of measurement of inclination by inclinometers.

  17. A comparative assessment of culture and serology in the diagnosis of brucellosis in dairy cattle.

    Science.gov (United States)

    O'Grady, D; Byrne, W; Kelleher, P; O'Callaghan, H; Kenny, K; Heneghan, T; Power, S; Egan, J; Ryan, F

    2014-03-01

    To investigate the usefulness of culture for the confirmation of brucellosis in cattle, a comparison of culture and serology was undertaken on 248 animals in four dairy herds where the disease was active. Paired supramammary (SM), retropharyngeal (RP), and internal iliac (IL) lymph nodes were cultured, and five serological tests were deployed: the microserum agglutination test (MSAT), complement fixation test (CFT), the indirect (iELISA) and competitive ELISA, and the fluorescence polarisation assay (FPA). Brucella abortus was isolated from 86.8% of animals on combined culture of all three lymph nodes. Individually, the highest isolation rate was from the RP (90.5% of culture positives). Of culture positive animals, 13.7% and 6.2% were positive from the RP and SM alone, respectively. Approximately half of the positive cultures yielded diagnosis of bovine brucellosis. While the MSAT and FPA were the most sensitive serological tests, a significant percentage of infected animals were undetectable using these standard serological assays.

  18. Genitourinary brucellosis: results of a multicentric study.

    Science.gov (United States)

    Erdem, H; Elaldi, N; Ak, O; Gulsun, S; Tekin, R; Ulug, M; Duygu, F; Sunnetcioglu, M; Tulek, N; Guler, S; Cag, Y; Kaya, S; Turker, N; Parlak, E; Demirdal, T; Ataman Hatipoglu, C; Avci, A; Bulut, C; Avci, M; Pekok, A; Savasci, U; Kaya, S; Sozen, H; Tasbakan, M; Guven, T; Bolukcu, S; Cesur, S; Sahin-Horasan, E; Kazak, E; Denk, A; Gonen, I; Karagoz, G; Haykir Solay, A; Alici, O; Kader, C; Senturk, G; Tosun, S; Turan, H; Baran, A I; Ozturk-Engin, D; Bozkurt, F; Deveci, O; Inan, A; Kadanali, A; Sayar, M S; Cetin, B; Yemisen, M; Naz, H; Gorenek, L; Agalar, C

    2014-11-01

    This study reviewed the clinical, laboratory, therapeutic and prognostic data on genitourinary involvement of brucellosis in this largest case series reported. This multicentre study pooled adult patients with genitourinary brucellar involvement from 34 centres treated between 2000 and 2013. Diagnosis of the disease was established by conventional methods. Overall 390 patients with genitourinary brucellosis (352 male, 90.2%) were pooled. In male patients, the most frequent involved site was the scrotal area (n=327, 83.8%), as epididymo-orchitis (n=204, 58%), orchitis (n=112, 31.8%) and epididymitis (n=11, 3.1%). In female patients, pyelonephritis (n=33/38, 86.8%) was significantly higher than in male patients (n=11/352, 3.1%; pbrucellosis occurred in one patient. A localized scrotal infection in men or pyelonephritis in women in the absence of leucocytosis and with mild to moderate increases in inflammatory markers should signal the possibility of brucellar genitourinary disease.

  19. Gray AAF/Fort Lewis, Washington. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

    Science.gov (United States)

    1982-12-14

    with dust ad/or sand is included in this summary only when visibility is reduced to A- 3 / TLAL CLT vTCLC3Y DPOH " , AT-r, SEQvI’T/ AO STATJCN NAME , EA ;s...93.5 94 .. .. 95.I 95.9 96.5 97. .97.7 97.8 98 .1 98.2 , 99.,.,. TOTAk NU BER OF OSFVATION, - -- -- - - -- LCEILING VERSUS VISIBILITY T - S Rv. F EA ...88.6 88.6 868.6 88.6 88.6 88.6 88.6 88.6 R8.6 5 . _,𔃿, , 93.1 9 3. 1 .. 93o41. 3 9313 93.3 93.3 1 9𔃻.13 91.3 93.3 9.3-1A-2.lT -5.3 ;3.9 95.5 95.7 9S7

  20. A new method for concentration analysis of bacterial endotoxins in perfluorocarbon

    Science.gov (United States)

    Chen, Dan-Dan; Feng, Xiao-Ming; Wang, Chun-Ren; Huang, Qing-Quan; Yang, Zhao-Peng; Meng, Qing-Yuan

    2014-12-01

    This communication demonstrates the feasibility of the gel-clot method for the analysis of bacterial endotoxins in water extracts of perfluorocarbon which is a water insoluble liquid medical device. Perfluorocarbon (10 mL) was shaken with 10mL water for 15 min at 2000 r/min and the endotoxin present was extracted to the aqueous phase without interference inhibition/enhancement of the product and the recovery of endotoxin added to perfluorocarbon was determined. A validation study confirmed that endotoxins presented in perfluorocarbon pass over into the aqueous phase at concentrations of 20, 10 and 5 EU/mL with recoveries from 86.8% to 96.8%. Therefore, the gel-clot test is suitable for detecting bacterial endotoxins in perfluorocarbon which is a water insoluble medical device.

  1. Cultural diversity among nursing students: reanalysis of the cultural awareness scale.

    Science.gov (United States)

    Rew, Lynn; Becker, Heather; Chontichachalalauk, Jiraporn; Lee, H Y

    2014-02-01

    Nurses are educated to provide culturally competent care. Cultural competence begins with cultural awareness, a concept previously measured with the Cultural Awareness Scale (CAS). The purpose of this study was to reanalyze the CAS to determine construct validity and differences in cultural awareness among students of varying educational levels and experiences. The sample consisted of 150 nursing students (92% female, 33.6% racial minorities). Confirmatory factor analysis yielded three factors (CFI = 0.868, TLI = 0.854, RMSEA = 0.065, and SRMR = 0.086). Cronbach's alpha ranged from 0.70 to 0.89. There were significant differences among educational levels, with lower division BSN students generally scoring higher than upper division and master's of science in nursing students. Students who had taken courses on cultural diversity or global health generally outscored those who had not taken such courses. Findings support the validity of the CAS and its applicability to research studies of cultural awareness in nursing.

  2. Pore structure of the activated coconut shell charcoal carbon

    Science.gov (United States)

    Budi, E.; Nasbey, H.; Yuniarti, B. D. P.; Nurmayatri, Y.; Fahdiana, J.; Budi, A. S.

    2014-09-01

    The development of activated carbon from coconut shell charcoal has been investigated by using physical method to determine the influence of activation parameters in term of temperature, argon gas pressure and time period on the pore structure of the activated carbon. The coconut shell charcoal was produced by pyrolisis process at temperature of about 75 - 150 °C for 6 hours. The charcoal was activated at various temperature (532, 700 and 868 °C), argon gas pressure (6.59, 15 and 23.4 kgf/cm2) and time period of (10, 60 and 120 minutes). The results showed that the pores size were reduced and distributed uniformly as the activation parameters are increased.

  3. The influence of parent education and family income on child achievement: the indirect role of parental expectations and the home environment.

    Science.gov (United States)

    Davis-Kean, Pamela E

    2005-06-01

    This study examined the process of how socioeconomic status, specifically parents' education and income, indirectly relates to children's academic achievement through parents' beliefs and behaviors. Data from a national, cross-sectional study of children were used for this study. The subjects were 868 8-12-year-olds, divided approximately equally across gender (436 females, 433 males). This sample was 49% non-Hispanic European American and 47% African American. Using structural equation modeling techniques, the author found that the socioeconomic factors were related indirectly to children's academic achievement through parents' beliefs and behaviors but that the process of these relations was different by racial group. Parents' years of schooling also was found to be an important socioeconomic factor to take into consideration in both policy and research when looking at school-age children.

  4. Service Lifetime Estimation of EPDM Rubber Based on Accelerated Aging Tests

    Science.gov (United States)

    Liu, Jie; Li, Xiangbo; Xu, Likun; He, Tao

    2017-02-01

    Service lifetime of ethylene propylene diene monomer (EPDM) rubber at room temperature (25 °C) was estimated based on accelerated aging tests. The study followed sealing stress loss on compressed cylinder samples by compression stress relaxation methods. The results showed that the cylinder samples of EPDM can quickly reach the physical relaxation equilibrium by using the over-compression method. The non-Arrhenius behavior occurred at the lowest aging temperature. A significant linear relationship was observed between compression set values and normalized stress decay results, and the relationship was not related to the ambient temperature of aging. It was estimated that the sealing stress loss in view of practical application would occur after around 86.8 years at 25 °C. The estimations at 25 °C based on the non-Arrhenius behavior were in agreement with compression set data from storage aging tests in natural environment.

  5. 禽类原始生殖细胞的迁移能力%Migration of avian primordial germ cells

    Institute of Scientific and Technical Information of China (English)

    李赞东; 李相芝; 赵东风; Takashi KUWANA

    2003-01-01

    Blood samples were collected from chicken embryos at stage 11-15,and labeled with fluorescent dye PKH26.Primordial germ cells (PGCs)were then isolated from blood samples by nycodenz density gradient centrifugation.After PGCs were labeled and isolated,about 200 PGCs in one microliter were injected into the subgerminal cavity of quail blastoderm at stageX.After 48 hours incubation,chicken PGCs were identified by fluorescent microscopy.Red fluorescence emitted from PKH26 labeled chicken PGCs was observed in the head, the heart and the developing gonadal anlage of quail embryos.The result suggests that chicken PGCs still keep migration ability after 56 hours[Acta Zoologica Sinica 49(6):868-872,2003].

  6. RNA-binding protein VICKZ is expressed in a germinal center associated pattern among lymphoma subtypes

    DEFF Research Database (Denmark)

    Natkunam, Y.; Vainer, G.; Zhao, S.C.;

    2005-01-01

    to the cytoplasm. Among 868 non-Hodgkin and Hodgkin lymphomas tested by immunohistochemistry on tissue microarrays, staining for VICKZ protein was present in 76% (126/165) of follicular lymphoma, 78% (155/200) of DLBCL, 90% (9/10) of mediastinal large B-cell lymphoma, and 100% (2/2) of Burkitt lymphoma. A subset...... of mantle cell lymphoma (11%, 2/19), extranodal (8%, 2/25), and nodal (20%, 1/5) marginal zone lymphoma and lymphoblastic lymphoma (25%, 4/13), showed VICKZ staining. The majority of lymphocyte predominant Hodgkin (92%, 12/13) and classical Hodgkin (94%, 101/108) lymphoma were found to be positive. Among T......Recent effort in the molecular characterization of diffuse large B-cell lymphoma (DLBCL) has led to the recognition that patients with DLBCL of germinal center origin exhibit a better overall survival. Thus, identification and characterization of markers of germinal center derivation...

  7. AcEST: BP919940 [AcEST

    Lifescience Database Archive (English)

    Full Text Available YMU001_000130_H08 531 Adiantum capillus-veneris mRNA. clone: YMU001_000130_H08. BP91994...0 CL868Contig1 Show BP919940 Clone id YMU001_000130_H08 Library YMU01 Length 531 Definition Adiantum cap...illus-veneris mRNA. clone: YMU001_000130_H08. Accession BP919940 Tissue type prothallium Developmental stage..., Nucleic Acids Res. 25:3389-3402. Query= BP919940|Adiantum capillus-veneris mRNA, clone: YMU001_000130_H08.... search programs, Nucleic Acids Res. 25:3389-3402. Query= BP919940|Adiantum capillus-veneris mRNA, clone: YM

  8. Multimodal discrimination of immune cells using a combination of Raman spectroscopy and digital holographic microscopy

    Science.gov (United States)

    McReynolds, Naomi; Cooke, Fiona G. M.; Chen, Mingzhou; Powis, Simon J.; Dholakia, Kishan

    2017-03-01

    The ability to identify and characterise individual cells of the immune system under label-free conditions would be a significant advantage in biomedical and clinical studies where untouched and unmodified cells are required. We present a multi-modal system capable of simultaneously acquiring both single point Raman spectra and digital holographic images of single cells. We use this combined approach to identify and discriminate between immune cell populations CD4+ T cells, B cells and monocytes. We investigate several approaches to interpret the phase images including signal intensity histograms and texture analysis. Both modalities are independently able to discriminate between cell subsets and dual-modality may therefore be used a means for validation. We demonstrate here sensitivities achieved in the range of 86.8% to 100%, and specificities in the range of 85.4% to 100%. Additionally each modality provides information not available from the other providing both a molecular and a morphological signature of each cell.

  9. A triboelectric wind turbine for small-scale energy harvesting

    Science.gov (United States)

    Perez, Matthias; Boisseau, Sebastien; Geisler, Matthias; Despesse, Ghislain; Reboud, Jean Luc

    2016-11-01

    This paper deals with a rotational energy harvester including a Horizontal Axis Wind Turbine (HAWT), a cylindrical stator covered by several electrodes, and thin Teflon dielectric membranes hung on the rotor. The sliding contact of the Teflon membranes on the stator provides simultaneously large capacitance variations and a polarization source for the electrostatic converter by exploiting triboelectric phenomena. 1μW has been harvested at 4m/s; 130μW at 10m/s and 550μW at 20m/s with a 40mmØ device. In order to validate the energy harvesting chain, the airflow energy harvester has been connected to a power management circuit implementing Synchronous Electric Charge Extraction (SECE) to supply a wireless sensor node with temperature and acceleration measurements, transmitted to a computer at 868MHz.

  10. Vitamin D with calcium reduces mortality

    DEFF Research Database (Denmark)

    Rejnmark, Lars; Avenell, Alison; Masud, Tahir

    2012-01-01

    Introduction:Vitamin D may affect multiple health outcomes. If so, an effect on mortality is to be expected. Using pooled data from randomized controlled trials, we performed individual patient data (IPD) and trial level meta-analyses to assess mortality among participants randomized to either...... vitamin D alone or vitamin D with calcium.Subjects and Methods:Through a systematic literature search, we identified 24 randomized controlled trials reporting data on mortality in which vitamin D was given either alone or with calcium. From a total of 13 trials with more than 1000 participants each, eight......,528 randomized participants (86.8% females) with a median age of 70 (interquartile range, 62-77) yr. Vitamin D with or without calcium reduced mortality by 7% [hazard ratio, 0.93; 95% confidence interval (CI), 0.88-0.99]. However, vitamin D alone did not affect mortality, but risk of death was reduced if vitamin...

  11. Dicty_cDB: [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFB707 (Link to dictyBase) - - - Contig-U09871-1 VFB707P (Link... to Original site) VFB707F 226 VFB707Z 642 VFB707P 868 - - Show VFB707 Library VF (Link to library) Clone ID VFB707 (Link to dict...yBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U09871-1 Original site URL http://dict...e 2004.12.25 Homology vs DNA Score E Sequences producing significant alignments: (bits) Value N AC116957 |AC116957.2 Dict...yostelium discoideum chromosome 2 map 1685067-2090751 strain AX4, complete sequence. 1191 0.0 4

  12. Hombres Sanos: exposure and response to a social marketing HIV prevention campaign targeting heterosexually identified Latino men who have sex with men and women.

    Science.gov (United States)

    Martínez-Donate, Ana P; Zellner, Jennifer A; Fernández-Cerdeño, Araceli; Sañudo, Fernando; Hovell, Melbourne F; Sipan, Carol L; Engelberg, Moshe; Ji, Ming

    2009-10-01

    This study examined the reach and impact of a social marketing intervention to reduce HIV risk among heterosexually identified (HI) Latino men who have sex with men and women (MSMW). Repeated cross-sectional intercept surveys were conducted in selected community venues during and after the campaign with 1,137 HI Latino men. Of them, 6% were classified as HI Latino MSMW. On average, 85.9% of the heterosexual respondents and 86.8% of the HI MSMW subsample reported exposure to the campaign. Responses to the campaign included having made an appointment for a male health exam that included HIV testing and using condoms. Campaign exposure was significantly associated with HIV testing behavior and intentions and with knowledge of where to get tested. The campaign reached its underserved target audience and stimulated preventive behaviors. Social marketing represents a promising approach for HIV prevention among HI Latinos, in general, and HI Latino MSMW, in particular.

  13. The Effect of Training and Development on Employee Attitude as it Relates to Training and Work Proficiency

    Directory of Open Access Journals (Sweden)

    Debra L. Truitt

    2011-10-01

    Full Text Available It is incumbent on training and development professionals to design, implement, and evaluate the effectiveness of their programs in reducing disputes in workplace performance. This study explores the relationships between training experiences and attitudes and attitudes about perceived job proficiency. In a sample of 237 full-time salaried/exempt and hourly/nonexempt employees from one academic institution and three businesses in the states of Maryland, Delaware, and Arizona, the author finds a direct relationship between one’s positive training experiences and attitudes and one’s proficiency. In this study, 86.8% of those who had updated training had the most positive attitudes toward training (γ = .293, p < .05. Furthermore, 80% of those who had negative training attitudes also had negative views on their proficiency (γ = .465, p < .000.

  14. Antiferromagnetic and Orbital Ordering on a Diamond Lattice Near Quantum Criticality

    Science.gov (United States)

    Plumb, K. W.; Morey, J. R.; Rodriguez-Rivera, J. A.; Wu, Hui; Podlesnyak, A. A.; McQueen, T. M.; Broholm, C. L.

    2016-10-01

    We present neutron scattering measurements on powder samples of the spinel FeSc2S4 that reveal a previously unobserved magnetic ordering transition occurring at 11.8(2) K. Magnetic ordering occurs subsequent to a subtle cubic-to-tetragonal structural transition that distorts Fe coordinating sulfur tetrahedra and lifts the orbital degeneracy. The orbital ordering is not truly long ranged, but occurs over finite-sized domains that limit magnetic correlation lengths. The application of 1 GPa hydrostatic pressure appears to destabilize this Néel state, reducing the transition temperature to 8.6(8) K and redistributing magnetic spectral weight to higher energies. The relative magnitudes of ordered ⟨m ⟩2=3.1 (2 ) μB2 and fluctuating moments ⟨δ m ⟩=13 (1 ) μB2 show that the magnetically ordered state of FeSc2 S4 is drastically renormalized and close to criticality.

  15. Experimental Study on Scale-Up of Solid-Liquid Stirred Tank with an Intermig Impeller

    Science.gov (United States)

    Zhao, Hongliang; Zhao, Xing; Zhang, Lifeng; Yin, Pan

    2017-02-01

    The scale-up of a solid-liquid stirred tank with an Intermig impeller was characterized via experiments. Solid concentration, impeller just-off-bottom speed and power consumption were measured in stirred tanks of different scales. The scale-up criteria for achieving the same effect of solid suspension in small-scale and large-scale vessels were evaluated. The solids distribution improves if the operating conditions are held constant as the tank is scaled-up. The results of impeller just-off-bottom speed gave X = 0.868 in the scale-up relationship ND X = constant. Based on this criterion, the stirring power per unit volume obviously decreased at N = N js, and the power number ( N P) was approximately equal to 0.3 when the solids are uniformly distributed in the vessels.

  16. ADOLESCENT IDIOPATHIC SCOLIOSIS: EVALUATION ON THE EFFECT OF SCREW DENSITY IN THE CORRECTION

    Directory of Open Access Journals (Sweden)

    Enguer Beraldo Garcia

    2016-03-01

    Full Text Available ABSTRACT Objective: The objective was to investigate implant density or the number of screws correlated with the correction of the main curve in patients undergoing surgery for adolescent idiopathic scoliosis (AIS. Methods: We evaluated 112 medical records: 33 patients with screw density of up to 50%, and 79 patients with a density of 100%; all patients underwent surgical correction by posterior approach with transpedicular fixation. Results: In the group of patients with screw density of up to 50% the residual Cobb median was 10°; in the group with 100% density, the median was 7°. Conclusion: Biostatistical analysis showed that the group with up to 50% of screw density presented correction rate of 82.1% and the group with 100% density had correction of about 86.8%. It is therefore concluded that the difference is statistically significant in favor of the fixation with 100% density (p =0.010.

  17. Organization of the cysts in bee (Hymenoptera, Apidae testis: number of spermatozoa per cyst

    Directory of Open Access Journals (Sweden)

    Cruz-Landim Carminda da

    2001-01-01

    Full Text Available The morphology of the cyst cells in Apis mellifera Linné, 1758, Scaptotrigona postica Latreille, 1804, and Melipona bicolor bicolor Lepeletier, 1836 testis, as well as the average number of spermatic cells are reported. The data indicates a supporting and nourrishing role of the cyst cells to the developing cystocytes. The counts of immature spermatozoa in the cysts show an average of 202.8 ± 21.2 spermatozoa for A. mellifera, 117.4 ± 8.68 for S. postica and 88.8 ± 15.57 for M. bicolor, which predict the occurrence of 8 mitotic cycles in the cystocytes of A. mellifera and 7 in the meliponines, considering that only one spermatozoom originates of each final spermatogonium.

  18. Impact of the inundation occurrence on the deep convection at continental scale from satellite observations and modeling experiments

    OpenAIRE

    Prigent, C.; Rochetin, N.; Aires, F.; Defer, E.; Grandpeix, J.Y.; Jimenez, C.; F. Papa

    2011-01-01

    ISI Document Delivery No.: 868AQ Times Cited: 1 Cited Reference Count: 41 Cited References: Adler RF, 2003, J HYDROMETEOROL, V4, P1147, DOI 10.1175/1525-7541(2003)0042.0.CO;2 Alsdorf DE, 2007, REV GEOPHYS, V45, DOI 10.1029/2006RG000197 ANTHES RA, 1977, MON WEATHER REV, V105, P270, DOI 10.1175/1520-0493(1977)1052.0.CO;2 Betts AK, 2009, J ADV MODEL EARTH SY, V1, DOI 10.3894/JAMES.2009.1.4 Bloom AA, 2010, SCIENCE, V327, P322, DOI 10.1126/science.1175176 Bony S, 2001, J ATMOS SCI, V58, P3158, DOI...

  19. High Q-factor Sapphire Whispering Gallery Mode Microwave Resonator at Single Photon Energies and milli-Kelvin Temperatures

    CERN Document Server

    Creedon, Daniel L; Farr, Warrick; Martinis, John M; Duty, Timothy L; Tobar, Michael E

    2011-01-01

    The microwave properties of a crystalline sapphire dielectric whispering gallery mode resonator have been measured at very low excitation strength (E/hf=1) and low temperatures (T = 30 mK). The measurements were sensitive enough to observe saturation due to a highly detuned electron spin resonance, which limited the loss tangent of the material to about 2e-8 measured at 13.868 and 13.259 GHz. Small power dependent frequency shifts were also measured which correspond to an added magnetic susceptibility of order 1e-9. This work shows that quantum limited microwave resonators with Q-factors > 1e8 are possible with the implementation of a sapphire whispering gallery mode system.

  20. A High-Resolution Human Contact Network for Infectious Disease Transmission

    CERN Document Server

    Salathé, Marcel; Lee, Jung Woo; Levis, Philip; Feldman, Marcus W; Jones, James H

    2010-01-01

    The most frequent infectious diseases in humans - and those with the highest potential for rapid pandemic spread - are usually transmitted via droplets during close proximity interactions (CPIs). Despite the importance of this transmission route, very little is known about the dynamic patterns of CPIs. Using wireless sensor network technology, we obtained high-resolution data of CPIs during a typical day at an American high school, permitting the reconstruction of the social network relevant for infectious disease transmission. At a 94% coverage, we collected 762,868 CPIs at a maximal distance of 3 meters among 788 individuals. The data revealed a high density network with typical small world properties and a relatively homogenous distribution of both interaction time and interaction partners among subjects. Computer simulations of the spread of an influenza-like disease on the weighted contact graph are in good agreement with absentee data during the most recent influenza season. Analysis of targeted immuniz...

  1. Potential Development of Liquid Smoke from Oil Palm Solid Waste as Biofungicides

    Directory of Open Access Journals (Sweden)

    Asri Gani

    2014-05-01

    Full Text Available This research investigated the potential utilization of solid waste from palm oil industry for liquid smoke production in Aceh Province, Indonesia. The liquid smoke can be applied as bio fungicides in agricultural field. Preliminary experiment on the use of liquid smoke as fungicide at Colletotrichum capsisi fungus which causes anthracnose disease on red pepper was also conducted. The survey on the existing potential/availability of palm oil mill in Aceh shows that there are 30 palm oil mills in eight districts with a total of production capacity 1020 ton/hour. Assuming that 10% of palm oil kernel shells are pyrolized into liquid smoke, Aceh province could produce about 23,868 ton of liquid smoke per year. The preliminary test result towards Colletotrichum capsisi fungus shows that the liquid smoke can be used as fungicides.

  2. The use of PCR technique in the identification of Mycobacterium species responsible for bovine tuberculosis in cattle and buffaloes in Pakistan.

    Science.gov (United States)

    Akhtar, Farah; Javed, Muhammad Tariq; Aziz-ur-Rehman; Khan, Muhammad Nisar; Akhtar, Pervez; Hussain, Sayed Misdaq; Aslam, Muhammad Sohaib; Kausar, Razia; Qamar, Mehwish; Cagiola, Monica

    2015-08-01

    Bovine tuberculosis is one of the important diseases of dairy and wild animals. The disease is prevalent all over the world, though developed countries have tremendously reduced the prevalence through eradication campaigns. The prevalence of disease in Pakistan on the basis of tuberculin testing or culture isolation of the organism has been reported previously. It is, however, important to use the latest diagnostic tools, i.e. PCR to confirm the type of Mycobacterium infecting the animals in Pakistan. Therefore, the present study was carried out to assess the utility of direct PCR on milk samples and nasal swabs to confirm the type of Mycobacterium infecting the animals. This study was carried out on 215 cattle and buffaloes of more than 2 years of age present at two livestock farms. The tuberculin results showed 22.5% prevalence at one farm and 25.9% at the other with an overall prevalence of 24.7%. The 92.5% of milk samples and/or nasal swabs showed positive PCR for Mycobacterium genus, 86.8% for Mycobacterium tuberculosis complex and 77.4% for Mycobacterium bovis. The M. bovis by PCR was detected in 13.2% of milk samples, 24.5% of nasal swabs and 39.6% of both milk samples + nasal swabs. The results suggested that there are 60% higher chance for a nasal swab to yield a positive PCR for M. bovis than the milk sample. It can be concluded from the present study that tuberculin testing is a useful method in studying the prevalence of disease as the PCR for Mycobacterium genus was positive in 92.5%, M. tuberculosis complex in 86.8% and Mycobacterium bovis in 77.4% cases.

  3. 彩超联合钼靶x线在乳腺普查中的应用价值%The value of color Dopplor ultrasound and mammography combined for the diognsis of breast cancer in the breast image screening projects

    Institute of Scientific and Technical Information of China (English)

    王秀荣; 朱长征

    2013-01-01

    Objective:To evaluate the value of color Dopplor ultrasound and mammography combined for the diagnosis of breast cancer in the breast image screening project.Methods:7084 persons had undergone mammography and color Dopplor ultrasound and the suiting rate of diagnosis with pathology were statistical y analysed.Results:Suilting rate of diagnosis by mammography was 86.8%;suit ing rate by color Dopplor ultrasound was 88.7%,there isn’t statistical y difference between them (p>0.05),the suiting rate of diagnosis of color Dopplor ultrasound combined mammography was 96.2%,which had marked significant compared with mammography and color Dopplor ultrasound alone (p<0.05).Conclusion:Physical examination with color Dopplor ultrasound and mammography is the best method for breast cancer screening.%目的:探讨彩超与钼靶x线联合应用在乳腺筛查中的应用价值。方法:对7084人进行乳腺钼靶及彩超检查,并与病理诊断结果对照进行统计学分析。结果:彩超与病理诊断总符合率88.7%,钼靶与病理诊断总符合率86.8%,两者差异无显著性(p>0.05),彩超联合钼靶的符合率为96.2%,与单钼靶及单独彩超相比均有显著性差异(p<0.05)。结论:临床触诊+钼靶+彩超的模式是目前进行乳腺普查的最佳模式。

  4. Clinical experience for treating secondary amenorrhea with the Yijing decoction according to astronomical calendar%结合天文历法服用益经汤治疗继发性闭经临床体会

    Institute of Scientific and Technical Information of China (English)

    刘亚琴; 孙得利

    2015-01-01

    Objective: Combination of astronomical calendar and the Yijing decoction was applied to treat secondary amenorrhea. Methods: 38 patients with secondary amenorrhea were included in the study, to summarize the clinical experience. Results: In one course, 21 cases were menstruation recovery of fancy. In two courses of treatment, 9 cases were menstruation recovery of fancy. In three courses of treatment, 3 cases were menstruation recovery of fancy; there are still 5 patients of fail menstruation; the total efifciency was 86.8%. Conclusion: Combination of astronomical calendar and the Yijing decoction has signiifcant effects on secondary amenorrhea.%目的:服用益经汤结合天文历法治疗继发性闭经。方法:选取38例继发性闭经患者,在满月(每月阴历十五)前一周开始服用益经汤,总结临床体会。结果:38例患者治疗一个疗程后,月经恢复来潮21例,治疗两个疗程后,月经恢复来潮9例,治疗三个疗程后,月经恢复来潮3例,仍然有5例患者月经未来潮,总有效率为86.8%。结论:结合天文历法服用益经汤治疗继发性闭经疗效显著。

  5. Bird system based on ARM and ZigBee technology airport intelligent%基于ARM、ZigBee技术的机场智能化驱鸟系统设计

    Institute of Scientific and Technical Information of China (English)

    赵超; 陈寿元; 邵增珍

    2013-01-01

    介绍了一种基于ARM、ZigBee技术的机场智能化防鸟撞驱鸟系统.该系统采用无线监测网络结合上位机监控管理中心框架,采用低功耗控制芯片STM32Fl03RBT、Maxstream公司的XBee模块、短波数传电台TDX-868A,融合无线传感器网络、GPS技术、电子罗盘和ARM等工控领域的技术,采用星型网络的拓扑结构,实现了对机场区域的鸟情监测,利用数据挖掘技术,对鸟情信息进行数据分析,预报鸟情,从根本上防止鸟撞事故的发生.%A ARM ZigBee technology airport intelligent anti-bird strike bird is introduced. The system uses a wireless monitoring network combined with the the PC monitoring center framework, the use of low-power control chip STM32F103RBT, the Maxstream company XBee module, shortwave data transmission radio TDX-868A, the integration of wireless sensor networks, GPS technology, electronic compass and ARM IPC the field of technology, using a star network topology, bird Surveillance in the airport area, using data mining techniques of bird intelligence information, data analysis, forecasting birds love, fundamentally prevent bird strike accidents.

  6. Production of Ni-Fe alloy from nickeliferous laterite ore by prereduction-electric furnace smelting separation%红土镍矿转底炉预还原-电炉熔分制取镍铁合金

    Institute of Scientific and Technical Information of China (English)

    范兴祥; 董海刚; 汪云华; 吴跃东; 李柏榆; 李博捷; 赵家春; 暂林寒

    2012-01-01

    对某红土镍矿采用转底炉预还原-电炉熔分工艺制取镍铁合金进行研究.实验结果表明:根据矿石性质,选择合适的渣型为SiO2-MgO-CaO-FeO四元渣系,在熔剂石灰配比为25%,还原剂配比为3.5%,预还原温度为1 150℃,预还原时间为30 min,电炉熔分温度为1 450℃,熔分时间为15 min的条件下,经转底炉预还原-电炉熔分后,获得镍质量分数为8.68%、镍回收率97.62%、铁质量分数为86.23%的镍铁合金,该合金可用作不锈钢生产原料.%The production of Ni-Fe alloy from nickeliferous laterite ore was studied by rotary hearth furnace prereduction-electric furnace smelting separation. The results show that a SiOi-MgO-CaO-FeO slag style is chosen according to the characteristic of the nickeliferous laterite ore and Ni-Fe alloy with 8.68% Ni (mass fraction), Ni 97.62% recovery and 86.23% Fe is obtained under the conditions of lime dosage 25%, reductant coke powder dosage 3.5%, prereduction temperature 1 150 ℃, prereduction time 30 min, smelting temperature 1 450 ℃, smelting time 15 rain, respectively, which can be used as the raw material of production of stainless steel.

  7. 奇正青鹏膏剂治疗膝关节骨关节炎疼痛的临床疗效分析%The efficacy of Qing-peng plaster in relieving pain of patients with osteoarthritis

    Institute of Scientific and Technical Information of China (English)

    赵凯; 张翔; 黄明华

    2011-01-01

    Objective To study the clinical effect of Qing - peng plaster for relieving pain of patients with osteoarthritis. Methods A retrospective analysis was made to study therapeutic results in a total of 156 patients with osteoarthritis of knee by Qing - peng plaster. They were divided into group A ( n = 88 cases ) treated with Qing - peng plaster and group B ( n = 68 cases ) treated with physiotherapy. Results CR + PR rates of two groups were 86.8% and 35.6% respectively ( P <0.05 ). Conclusion Qing - peng plaster is effective in relieving pain of patients with osteoarthritis of knee.%目的 验证奇正青鹏膏剂治疗骨性关节炎疼痛的临床疗效.方法 回顾性分析156例膝关节骨关节炎病人,分为青鹏膏组88例(主要应用奇正青鹏膏剂),理疗组68例进行临床对比观察.理疗组采用超短波治疗.结果 青鹏膏组和理疗组的完全缓解(CR)+部分缓解(PR) 率分别为86.8%和35.6%,两组比较差异有统计学意义(P<0.05).结论 奇正青鹏膏剂是缓解膝关节骨关节炎疼痛的一种有效药物.

  8. [Simulation study on the effect of salinity on the adsorption behavior of mercury in wastewater-irrigated area].

    Science.gov (United States)

    Zheng, Shun-An; Li, Xiao-Hua; Xu, Zhi-Yu

    2014-05-01

    This study was designed to pinpoint the impact of salinity ( NaCl and Na2SO4, added at salinity levels of 0-5%, respectively) on the adsorption behavior of mercury in wastewater-irrigated areas of Tianjin City by batch and kinetic experiments. The results showed that, the Langmuir isotherm and the Elovich equation can well fitted batch and kinetic experimental data, respectively. As NaCI spiked in soil, Hg( II) adsorption capacity and strength had marked decreases, from 868.64 mgkg-1 and 1. 32 at control to 357.48 mgkg-1 and 0.63 at 5% salinity level of NaCI, respectively. As Na2SO4 spiked in soil, Hg(II) adsorption capacity (parameter qm in Langmuir isotherm) and strength (parameter k in Langmuir isotherm) changed slightly, from 868.64 mg kg-1 and 1.32 at control to 739.44 mg.kg-1 and 1. 18 at 5% salinity level of Na2 SO4, respectively. Kinetic data showed that, Hg( II) adsorption rate (parameter b in Elovich equation) in soil was not influenced by Na2SO, addition. However, the addition of NaC1 had a great effect on mercury adsorption rate. Hg(II ) adsorption capacity as a function of CI- or SO(2-)(4) content in soil could be simulated by the natural logarithm model, while Hg( II ) adsorption rate as a function of CI- content in soil could be simulated by the linear model. The study manifested that NaCI can significantly increase migration of Hg( II ) in the soil irrigated with wastewater, which may enhance Hg( II) bioavailability in the soil and cause a hazard to surface water. Especially, it will be harmful to human body through the food chain.

  9. Risk of inn-hospital infection in neonatal care unit Riesgo de infección intrahospitalaria en la unidad de cuidados neonatales

    Directory of Open Access Journals (Sweden)

    Eloida García Hernández

    Full Text Available Background: The newborn present the highest rates of nosocomial infections, which are an alarming challenge in the neonatology units. Objectives: to identify the risk factors of nosocomial infections and to determine the incidence rate of hospital infection in the newborn. Methods: Analytic study of cases and controls of nosocomial infections present in the neonatology service of the Universitary Provincial Hospital of Cienfuegos, from June 2002 to June 2003. Results and Conclusions: The incidence rate of intra-hospital infection was of 4,58 X 100. Children with more than 7 days old have 8,68 times more risk of suffering from that infection than those with less days. The infectious agent that could be isolated was that of Staphylococcus Coagulasa negative (20%.
    Fundamento: Los recién nacidos presentan las tasas más elevadas de infecciones nosocomiales, las cuales representan un desafío creciente en las Unidades de Neonatología. Objetivo: Identificar los factores de riesgo de infecciones nosocomiales en recien nacidos. Métodos: Estudio analítico de casos y controles, de las infecciones nosocomiales ocurridas en el Servicio de Neonatología del Hospital Provincial Universitario de Cienfuegos, desde junio de 2002 hasta junio de 2003. Resultados y conclusiones: La tasa de incidencia de infección intrahospitalaria fue de 4,58 por cada 100 egresos, los niños mayores de 7 días, tienen 8,68 veces más probabilidad de contraer una infección, que los menores de esa edad, el agente infeccioso que se aisló con mayor frecuencia fue el Estafilococo coagulasa negativo (20 %.

  10. Diamonds in meteorites – Raman mapping and cathodoluminescence studies

    Directory of Open Access Journals (Sweden)

    A.T. Karczemska

    2010-11-01

    Full Text Available diversity among the diversity of other extraterrestrial carbon phases. The main subject of research shown here are example meteorites consisting diamonds: ureilites DaG 868 and Dho 3013. Results are compared with previous investigations. Diamonds exist in many different meteorites, interplanetary dust particles (IDPs and in comets dust. Origin of different diamonds is still debated among the scientists, two main possibilities are taken into consideration CVD process or shock metamorphism. Understanding laboratory techniques of manufacturing diamond helps in understanding the processes taking place in the Space. From the other side, the new findings and discoveries give the new insight to material science and laboratory techniques.Design/methodology/approach: The samples were examined with different methods, the most investigations presented here are Raman Mapping and Cathodoluminescence (CL.Findings: Diamonds have been found in different samples with different shock stages. It means that not all diamonds in urelites could have shock origin. Diamonds from examined samples show high diversity, they exist in different sizes, from nanodiamonds to micrometer sizes diamonds and in different polytypes. Shifts of Raman diamond peaks indicates this.Research limitations/implications: Results show the possibilities of creating the new diamond-based materials similar to those found in meteorites. Diamond polytypes are not well characterized yet and could give some surprises for materials science. For future research it would be interesting to apply more methods such as X-ray diffraction or HRTEM.Originality/value: SEM+BSE+EDS+CL results and Raman imaging results of DaG 868 and Dho 1303 ureilites are shown for the first time.

  11. Evaluation of Ovarian Reserve with Anti-Müllerian Hormone in Familial Mediterranean Fever

    Directory of Open Access Journals (Sweden)

    Ali Şahin

    2015-01-01

    Full Text Available Objective. To investigate ovarian reserves in attack-free familial Mediterranean fever (AF-FMF patients at the reproductive age by anti-Müllerian hormone (AMH, antral follicle count (AFC, ovarian volume, and hormonal parameters. Methods. Thirty-three AF-FMF patients aging 18–45 years and 34 healthy women were enrolled and FSH, LH, E2, PRL, and AMH levels were measured in the morning blood samples at 2nd–4th days of menstruation by ELISA. Concomitant pelvic ultrasonography was performed to calculate AFC and ovarian volumes. Results. In FMF patient group, median AMH levels were statistically significantly lower in the M69V mutation positive group than in the negative ones (P=0.018. There was no statistically significant difference in median AMH levels between E148Q mutation positive patients and the negative ones (P=0.920. There was also no statistically significant difference in median AMH levels between M680I mutation positive patients and the negative ones (P=0.868. No statistically significant difference was observed in median AMH levels between patients who had at least one mutation and those with no mutations (P=0.868. We realized that there was no difference in comparisons between ovarian volumes, number of follicles, and AMH levels ovarian reserves when compared with FMF patients and healthy individuals. Conclusions. Ovarian reserves of FMF pateints were similar to those of healthy subjects according to AMH. However, AMH levels were lower in FMF patients with M694V mutation.

  12. 石墨炉原子吸收光谱法测定醋纤丝束中的砷和铅%Determination of As and Pb in Cellulose Acetate Tow by Graphite Furnace Atomic Absorption Spectrometry

    Institute of Scientific and Technical Information of China (English)

    李文璟; 张修华; 张胜华; 沈军; 曾强; 王惠; 梁琴

    2011-01-01

    采用HNO3-H2O2消化体系,应用石墨炉原子吸收光谱法对10种醋酸纤维丝束(醋纤丝束)中砷和铅的含量进行了测定.结果表明,该方法测定醋纤丝束中的砷、铅具有良好的线性关系,相关系数分别为0.9991、0.9989,砷、铅的定量检出限分别为0.450μg·L-1、0.799 μg·L-1,回收率分别为86.8%~99.6%、92.0%~103.8%.该方法简便、快速、准确度高、重复性好,可用于醋纤丝束中砷、铅的批量测定.%The content of As and Pb in 10 kinds of cellulose acetate tow were determined with graphite furnace atomic absorption spectrometry(GF-AAS) after digested with HNO3 and H2 O2. The results indicated that the method took on good linear relationships. For As and Pb, the correlation coefficients, the detection limit,the recoveries were 0. 9991 and 0. 9989, 0. 450 μg · L-1 and 0. 799 μg · L-1 ,86.8% ~99. 6% and 92.0% ~103.8%, respectively. The proposed method was simple, fast and accurate, which could be applied to determine As and Pb in cellulose acetate tow in bulks.

  13. Ru/TiO2催化剂上甘油氢解制1,2-丙二醇%Hydrogenolysis of Glycerol to 1,2-Propanediol over Ru/TiO2 Catalyst

    Institute of Scientific and Technical Information of China (English)

    冯建; 熊伟; 贾云; 王金波; 刘德蓉; 陈华; 李贤均

    2011-01-01

    采用浸渍法制备了负载型Ru/TiO2催化剂,利用X射线衍射、X射线光电子能谱、高分辨透射电镜、N2吸附和电感耦合等离子体原子发射光谱等方法对催化剂进行了表征,并考察了反应温度、H2压力、甘油溶液浓度、催化剂用量和碱性添加物等因素对Ru/TiO2上甘油氢解反应性能的影响.结果表明,在170℃和3MPa的温和反应条件下,以LiOH为添加物,甘油转化率和1,2-丙二醇选择性分别高达89.6%和86.8%.%The supported Ru/TiO2 catalyst was prepared by the impregnation method. The physicochemical properties of the catalyst were characterized by X-ray diffraction, X-ray photoelectron spectroscopy, high-resolution transmission electron microscopy, N2 adsorption, and inductively coupled plasma-atomic emission spectroscopy. The effects of reaction temperature, hydrogen pressure, glycerol concentration, catalyst amount, and base additives on the catalytic performance of RU/TiO2 in the glycerol hydrogenolysis reaction were investigated. Under mild reaction conditions (170 ℃, 3 Mpa), using LiOH as additive, the conversion of glycerol and the selectivity for 1,2-propanediol were as high as 89.6% and 86.8%, respectively.

  14. 聚乙烯醇缩丁醛溶液组分对Al2O3流延成型的影响%Effect of Characteristics of Polyvinyl Butyral on Al2O3 Tape Casting Slurry

    Institute of Scientific and Technical Information of China (English)

    涂从红; 吴黎; 朱丽慧; 黄清伟

    2011-01-01

    The effect of solubility, film-forming ability and the dispersion of polyvinyl butyral (PVB) on Al2O3 tape casting slurry were studied. The results show that the PVB polymer solution exhibits the lowest viscosity in the binary solvent(EtOH)/Xylene of 60% ethyl alcohol. The viscosity of slurry is 868 mPa ·s in the absence of dispersant whereas the viscosity decreases to 17 mpa·s with 0.5% PVB as the dispersant at the shear rate 50 s-1. When 8% PVB is added as the binder in the slurry, the slurry exhibits lower viscosity; the green tape shows better film-forming ability and has no obvious defaults.%研究了Al2O3流延浆料中聚乙烯醇缩丁醛(PVB)的溶解性、成膜性及其对氧化铝粉体的分散作用.实验结果表明,PVB溶解于二元混合溶剂乙醇/二甲苯,当乙醇含量为60%时,粘度最低,溶解性最佳;PVB用作分散剂,当用量为0.5%,剪切速率为50 s-1时,系统粘度从868 mPa·s降到17 mpa·s;PVB用作粘结剂,用量为8%时,流延生片无明显缺陷,流延浆料粘度较低,成膜性能好.

  15. Within- and between-session reliability of power, force, and rate of force development during the power clean.

    Science.gov (United States)

    Comfort, Paul

    2013-05-01

    Although there has been extensive research regarding the power clean, its application to sports performance, and use as a measure of assessing changes in performance, no research has determined the reliability assessing the kinetics of the power clean across testing session. The aim of this study was to determine the within- and between-session reliability of kinetic variables during the power clean. Twelve professional rugby league players (age 24.5 ± 2.1 years; height 182.86 ± 6.97 cm; body mass 92.85 ± 5.67 kg; 1 repetition maximum [1RM] power clean 102.50 ± 10.35 kg) performed 3 sets of 3 repetitions of power cleans at 70% of their 1RM, while standing on a force plate, to determine within-session reliability and repeated on 3 separate occasions to determine reliability between sessions. Intraclass correlation coefficients revealed a high reliability within- (r ≥ 0.969) and between-sessions (r ≥ 0.988). Repeated-measures analysis of variance showed no significant difference (p > 0.05) in peak vertical ground reaction force, rate of force development, and peak power between sessions, with small standard error of the measurements and smallest detectable differences for each kinetic variable (3.13 and 8.68 N; 84.39 and 233.93 N·s; 24.54 and 68.01 W, respectively). Therefore, to identify a meaningful change in performance, the strength and conditioning coach should look for a change in peak force ≥8.68 N, rate of force development ≥24.54 N·s, and a change in peak power ≥68.01 W to signify an adaptive response to training, which is greater than the variance between sessions, in trained athletes proficient at performing the power clean.

  16. Establishment of a pipeline to analyse non-synonymous SNPs in Bos taurus

    Directory of Open Access Journals (Sweden)

    Schreiber Mark

    2006-11-01

    Full Text Available Abstract Background Single nucleotide polymorphisms (SNPs are an abundant form of genetic variation in the genome of every species and are useful for gene mapping and association studies. Of particular interest are non-synonymous SNPs, which may alter protein function and phenotype. We therefore examined bovine expressed sequences for non-synonymous SNPs and validated and tested selected SNPs for their association with measured traits. Results Over 500,000 public bovine expressed sequence tagged (EST sequences were used to search for coding SNPs (cSNPs. A total of 15,353 SNPs were detected in the transcribed sequences studied, of which 6,325 were predicted to be coding SNPs with the remaining 9,028 SNPs presumed to be in untranslated regions. Of the cSNPs detected, 2,868 were predicted to result in a change in the amino acid encoded. In order to determine the actual number of non-synonymous polymorphic SNPs we designed assays for 920 of the putative SNPs. These SNPs were then genotyped through a panel of cattle DNA pools using chip-based MALDI-TOF mass spectrometry. Of the SNPs tested, 29% were found to be polymorphic with a minor allele frequency >10%. A subset of the SNPs was genotyped through animal resources in order to look for association with age of puberty, facial eczema resistance or meat yield. Three SNPs were nominally associated with resistance to the disease facial eczema (P Conclusion We have identified 15,353 putative SNPs in or close to bovine genes and 2,868 of these SNPs were predicted to be non-synonymous. Approximately 29% of the non-synonymous SNPs were polymorphic and common with a minor allele frequency >10%. Of the SNPs detected in this study, 99% have not been previously reported. These novel SNPs will be useful for association studies or gene mapping.

  17. 颞下颌关节紊乱病的MRI观察%MR imaging of temporomadibular joint dysfunction

    Institute of Scientific and Technical Information of China (English)

    王仁飞; 吕思平; 森家祥行; 海原真治; 竹信保尚

    2001-01-01

    目的 应用核磁共振技术(MRI)检查颞下颌关节紊乱病(TMD)。方法 观察61例颞下关节紊乱病患者的关节盘(Disc)位置和形态改变,并对照出现的临床表现进行分析,以探讨在诊断中的意义。结果 显示在所有TMD患者的关节中,86.8%有Disc前移位;80.9%有Disc形态改变;伴关节弹响、张口受限、关节破碎音或磨擦音等症状的关节中,MRI也显示Disc和髁突有不同程度的改变。结论 MRI是一种有前途的颞下颌关节紊乱病诊断方法。%Objective To investigate the magnetic resonance imaging(MRI) ofthe temporomandibular joint dysfunction(TMD). Methods We examined 68 suffered joints of 61 TMD patients by MRI and observed the placement and shape of the disc. Results MR imaging depicted anterior disc displacement in 86.8% of the symptomatic joints and shape changing in 80.9% of the joints.The disc and condylar have different in the joints with different symptoms. Conclusion MRI is one of the effective examing ways of the diagnosis of TMD.

  18. 柳州市君武森林公园旅游环境容量研究%The Accommodation Study of Traveling Environment of Junwu Forest Park in Liuzhou

    Institute of Scientific and Technical Information of China (English)

    黎森

    2012-01-01

    将森林公园的游客规模控制在合理的范围内,才能处理好森林旅游开发与保护之间的关系。以柳州市君武森林公园为例,在实地调查的基础上,采用线路法、设施法对公园的旅游环境容量及游客容量进行测算。通过研究发现,君武森林公园的年旅游环境容量为868 770人次,年游客容量为271 362人次,公园游客容量受旅游设施最大容纳值的限制,目前公园的年实际游客接待量远小于理论容量。通过本研究,为森林公园游客规模的合理控制提供科学依据。%To control the tourist scale of the park into a reasonable range and well handle the relationship between the tourism development and protection, this thesis, based on field investigation, takes Junwu Forest Park in Liuzhou for example and adopt the methods of tour road and facilities to estimate the environmental and traveling accommodation of the park. Through come to and accommodate about 271 the limit of the max accommodation. the study, it is found that every year the park can allow 868 770 people to 362 travelers to visit. As a result, the traveler capacity of the park is within At present, the actual annual capacity of accommodating travelers into the park is lower than the theoretical capacity. Thus this study will provide some scientific evidence for controlling the tourist scale of the park to a reasonable range.

  19. Prevalência de fatores de risco para Síndrome Coronariana aguda em pacientes atendidos em uma emergência Prevalencia de los factores de riesgo para el Síndrome Coronario agudo en los pacientes tratados en una emergencia Prevalence of risk factors for acute Coronary Syndrome in patients treated in an emergency

    Directory of Open Access Journals (Sweden)

    Karine Franke Lemos

    2010-03-01

    Full Text Available Objetivou-se caracterizar o perfil do paciente portador de Síndrome Coronária Aguda (SCA atendido em um serviço de emergência de Porto Alegre, Rio Grande do Sul, no que se refere aos fatores de risco. Estudo de prevalência entre agosto de 2007 e fevereiro de 2008. Para coleta de dados, foi utilizado um questionário, consulta ao prontuário e aferição de medidas antropométricas. Foram avaliados 152 pacientes com SCA, 63,8% do sexo masculino, idade média de 61±10,26 anos. Com diagnóstico de infarto agudo do miocárdio sem supradesnivelamento de ST em 50,7%, infarto agudo do miocárdio com supradesnivelamento de ST em 14,5% e angina instável em 34,9%. Os fatores de risco foram: sedentarismo (86,8%; sobrepeso e obesidade (77%; hipertensão arterial sistêmica (75,7%; história familiar (56,6%; estresse (52,6%; dislipidemia (44,7%; diabete mellitus (40,1%; tabagismo (39,5%; e ingesta de álcool (14,4%. Constatou-se uma alta prevalência de fatores de risco para SCA, necessitando de programas de educação em saúde, visando reduzir a morbi-mortalidade.Propusimos caracterizar el perfil de pacientes portador del Síndrome Coronariana Agudo (SCA en un servicio de emergencia de Porto Alegre, Rio Grande do Sul, Brasil, en lo que se refiere a los factores de riesgo. Estudio de prevalencia entre agosto/2007 y febrero/2008. Para la colecta de datos, fue utilizado un cuestionario, consulta al prontuario y contraste de medidas antropométricas. Fueron avaliados 152 pacientes con SCA, 63,8% de sexo masculino, edad media de 61 ± 10,26 años. Con diagnóstico de infarto agudo del miocardio sin elevación ST en 50,7%, infarto agudo del miocardio con elevación ST en 14,5% y angina inestable 34,9%. Los factores de riesgo fueron, sedentarismo (86,8%; sobrepeso y obesidad (77%; hipertensión arterial sistémica (75,7%; histórico familiar (56,6%; estrés (52,6%; dislipidemía (44,7%; diabetes mellitus (40,1%; tabaquismo (39,5%; ingetión de alcohol(14

  20. 蜘蛛丝基因MaSp1在转基因家蚕中的表达分析%Expression analysis of spiderdragline silk gene MaSp1 in the transgenic silkworm

    Institute of Scientific and Technical Information of China (English)

    韩冷; 张磊; 中垣雅雄

    2013-01-01

    To study the biological properties and structure of fibroin genes and proteins from transgenic silkworms,the transgenic silkworms were analyzed with inverse PCR,real-time PCR and co-IP methods.The results showed the following:(1) At the DNA level,MaSp1(major ampullate spidroin 1) was integrated into the B.mori chromosome at scaffold 868; (2)At the RNA level,the transcription of MaSp1 did not affect the transcription of Fib-H,Fib-L or P25,and the transcription level of MaSp1 was higher than that of Fib-H; (3) At the protein level,MaSpl,the foreign silk protein,had low abundance among the total silk fibroin proteins (approximate 2%).Additionally,it had a protein-protein interaction with Fib-L through its LBS (L-chain-binding site) region through intermolecular disulfide bonds.%利用反向PCR、定量PCR以及免疫共沉淀等方法分析研究转基因家蚕的丝素蛋白及基因的结构和性质.结果表明:(1)在DNA水平上,MaSp1基因整合进了家蚕的基因组,插入位点位于scaffold 868; (2)在RNA水平上,MaSp1的表达并不干扰其他3个基因(Fib-H,Fib-L and P25)的表达水平,并且外源基因MaSp1的表达水平略高于Fib-H; (3)在蛋白质水平上,MaSp1蛋白的丰度大约占丝素总蛋白的2%,而且通过自身的LBS区段和轻链蛋白(Fib-L)形成分子间二硫键,从而融入蚕丝蛋白复合体.

  1. Identifying the Probability for Ward Walking Independency in Stroke Patients Using the Berg Balance Scale and Walking Speed%用 Berg 平衡量表和步行速度判别脑卒中患者病区步行自立度的研究

    Institute of Scientific and Technical Information of China (English)

    刘迎晨; 瓮长水

    2013-01-01

    目的:探讨Berg平衡量表(Berg balance scale ,BBS)和步行速度(walking speed ,WS)对脑卒中患者病区步行自立度的判定价值。方法对80例脑卒中的BBS和WS进行测量和分析。结果 BBS和WS对病区步行自立度具有良好的判别效力,预测病区步行自立度正确率为91.3%;ROC曲线分析提示判断病区步行自立度的最佳BBS临界值为46.5分,敏感性5%,特异性为77.8%,ROC曲线下面积为0.900;判断病区步行自立度的最佳WS临界值为0.51 m/s ,其相应的敏感性为86.8%,特异性为88.9%,ROC 曲线下面积为0.956。结论 BBS和WS可以较好的判别脑卒中患者的病区步行自立度。%Objective To study the value of the Berg Balance Scale(BBS)and the walking speed(WS)for the identification about the ward walking independency in the stroke patients .Methods The BBS and the 10-m WS of 80 stroke patients were measured and analyzed . Results Using discriminate analysis ,the BBS and the 10m WS were found to be the good discriminators of independency and non-independ-ence group(accuracy 91.3% ) .Receiver operating characteristic(ROC)curves were employed to suggest cut-off scores and to determine over-all predictability ,for BBS :cut-off point 46.5 ,sensitivity 92.5% ,specificity 77.8% and area under ROC curve 0.900 ;and for WS :cut-off point 0.51 m/s ,sensitivity 86.8% ,specificity 88.9% % ,and area under ROC curve 0.956.Conclusion This study suggests that the BBS and the WS were a good measure for discriminating ward walking independency in the stroke patients .

  2. 顶空固相微萃取—气质分析罗勒叶香气成分%Study on aroma components of basil leaves by HS-SPME-GC-MS

    Institute of Scientific and Technical Information of China (English)

    陆占国; 王琳; 李伟; 林宝祥

    2011-01-01

    采用顶空固相微萃取和气相色谱—质谱分析白花罗勒叶的香气成分.萃取柱为DVB/CAR/PDMS时共检测出20种挥发性成分,解析出占总挥发性成分的98.273%的18种物质,主要成分是草蒿脑(42.879%),芳樟醇(36.214%),桉树脑(3.994%).萃取柱为CAR/PDMS时共检测出25个成分,解析出占总挥发性成分的98.827%的23种物质,主要成分是草蒿脑(48.100%),芳樟醇(24.868%),桉树脑(3.321%).萃取柱为CW/DVB时共检测出24个成分,解析出占总挥发性成分的100%的24种物质,主要成分是芳樟醇(36.056%)、草蒿脑(35.774%)、桉树脑(8.189%).%Aroma components of basil were extracted and analyzed by head space - solid phase microextraction and gas chromatography - mass spectrometry ( HS - SPME - GC - MS). Twenty components were detected by DVB/CAR/ PDMS column and 18 compounds ( 98.273% of total) were identified with main constituents of estragole (42.879%), linalool (36.214%) and cineole (3.994%) .Twenty five components were detected and 23 compounds ( 98.827% of total) were identified by CAR/PDMS column with estragole ( 48. 100%), linalool (24.868%) and cineole (3.321%). Twenty four components were detected and 24 compounds (100% of total) were identified by CW - DVB column with linalool (36.056%), estragole (35.774%) and cineole (8.189%).

  3. Analysis of the complement and molecular evolution of tRNA genes in cow

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    Barris Wesley C

    2009-04-01

    Full Text Available Abstract Background Detailed information regarding the number and organization of transfer RNA (tRNA genes at the genome level is becoming readily available with the increase of DNA sequencing of whole genomes. However the identification of functional tRNA genes is challenging for species that have large numbers of repetitive elements containing tRNA derived sequences, such as Bos taurus. Reliable identification and annotation of entire sets of tRNA genes allows the evolution of tRNA genes to be understood on a genomic scale. Results In this study, we explored the B. taurus genome using bioinformatics and comparative genomics approaches to catalogue and analyze cow tRNA genes. The initial analysis of the cow genome using tRNAscan-SE identified 31,868 putative tRNA genes and 189,183 pseudogenes, where 28,830 of the 31,868 predicted tRNA genes were classified as repetitive elements by the RepeatMasker program. We then used comparative genomics to further discriminate between functional tRNA genes and tRNA-derived sequences for the remaining set of 3,038 putative tRNA genes. For our analysis, we used the human, chimpanzee, mouse, rat, horse, dog, chicken and fugu genomes to predict that the number of active tRNA genes in cow lies in the vicinity of 439. Of this set, 150 tRNA genes were 100% identical in their sequences across all nine vertebrate genomes studied. Using clustering analyses, we identified a new tRNA-GlyCCC subfamily present in all analyzed mammalian genomes. We suggest that this subfamily originated from an ancestral tRNA-GlyGCC gene via a point mutation prior to the radiation of the mammalian lineages. Lastly, in a separate analysis we created phylogenetic profiles for each putative cow tRNA gene using a representative set of genomes to gain an overview of common evolutionary histories of tRNA genes. Conclusion The use of a combination of bioinformatics and comparative genomics approaches has allowed the confident identification of a

  4. Sealing weak gel completion fluid system for loose sand depleted reservoir%适用于疏松砂岩衰竭油藏的封堵型弱凝胶完井液体系

    Institute of Scientific and Technical Information of China (English)

    苏宇驰; 范白涛; 赵少伟

    2015-01-01

    Loose sandstone heavy oil reservoir is characterized as shallow buried,low temperature,poor lithology and loose cementation. It employs high-velocity water flow to conduct gravel packer completion,which result to leakage of completion fluid. Therefore a sealing weak gel completion fluid for loose sand depleted reservoir is developed. The recipe is as followed:filtering sea water+0.25%Na2CO3+0.7%FCNQ+2.0% filtrate reducer;Gel breaking liquid recipe:filtering sea water+3% new gel breaker +3%KCl. The reduction rate of leakage is greater than 90% when the fluid is applied,and core permeability recovery value comes to 86.8% with good reservoir protection. The fluid has strong suspension stability and good compatibility with later work fluids. It proves to be successful in SZ36-1 block,Bohai Oilfield.%疏松的砂岩稠油油藏储层具有的特征如下:温度低、埋藏浅、胶结疏松以及成岩性差等.该类油藏大都采用高速水流进行砾石充填完井,这就导致了完井液大量漏失等问题.基于以上考虑,在室内试验室研究出了适合疏松的砂岩稠油油藏储层的封堵型弱凝胶完井液.弱凝胶封堵配方:0.7%流型调节剂+2.0%降滤失剂+0.25%Na2CO3+海水.破胶液配方:3%新型破胶剂+3%KCl+海水.该体系使用后漏失降低率大于90%,解堵后岩心的渗透率恢复值达到86.8%,储层保护效果好,并且悬浮稳定性强,与后续工作液的配伍性好.渤海海域上绥中36-1区块广泛应用了本完井液体系并能很好地解决工程实际问题.

  5. Electricity Generation Characteristics of Microbial Fuel Cell ith Landfill Leachate as Fuel%以垃圾渗滤液为燃料的微生物燃料电池产电性能

    Institute of Scientific and Technical Information of China (English)

    张晓艳; 滕洪辉

    2011-01-01

    The double-chamber microbial fuel cell ( DCMFC ) with landfill leachate from some refuse dump of Siping City of Jilin Province as fuel was designed in the system with the bacteria in the titanium anode chamber separated from the titanium cathode chamber by a salt bridge. The effects of cathode chamber solution parameters on the electricity generation performance of DCMFC were researched. The results show that the DCMFC output power density is 12. 074 W/m2, open-circuit voltage is 1.13 V, internal resistance is 76. 868 O, under cathode chamber solution optimum conditions of 30 'C , 1.0 g/L H2O2, pH =2. 5, and 0. 5 g/L Na2SO4. After the DCMFC was continuously running for 30 days, the COD removal rate of landfill leachate reached to 95% , the adjust of cathode chamber operational parameters can improve the microbial fuel cell electricit generation.%以吉林省四平市某垃圾场渗滤液为燃料,纯钛板为负载微生物阳极和阴极,用盐桥转移电子方式组建双室微生物燃料电池(DCMFC).研究阴极室溶液电子受体质量浓度、pH值、温度等因素对输出功率密度、开路电压、内阻等电池性能的影响,并考察了对垃圾渗滤液的处理效果.实验结果表明,阴极溶液以1.0 g/L双氧水为电子受体,在pH=2.5、ρ(硫酸钠)=0.5 g/L、温度约为30 ℃的最佳实验条件下,该微生物燃料电池的输出功率密度达12.074 W/m2,开路电压为1.13 V,内阻为76.868 Ω.经过连续30 d的运行,垃圾渗滤液化学需氧量(COD)去除率达95%,表明选择恰当的阴极室溶液能提高微生物燃料电池的产电性能.

  6. Prevalence of and risk factors for asymptomatic inflammatory (NIH-IV prostatitis in Chinese men.

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    Chunlei Wu

    Full Text Available BACKGROUND: While many investigators have studied symptomatic prostatitis, little research has been done with regard to asymptomatic (NIH-IV prostatitis. PURPOSE: To describe the prevalence of and risk factors for NIH-IV prostatitis among a large male population. METHODS: The study population was comprised of 1,868 men at the second phase recruitment of a population-based cohort in China. Asymptomatic and symptomatic men were defined by the National Institutes of Health Chronic Prostatitis (CP Symptom Index. Meanwhile, EPS specimens and their leukocyte count were collected. Lifestyle and demographic characteristics were obtained through a questionnaire. RESULTS: Prevalence of NIH-IV prostatitis was 21.1% among 1,868 asymptomatic men aged 19-78 years and increased with age. After adjusteing for potential confounding variables (age, smoking habits, alcohol drinking habits, education, physical activity, hypertension, dyslipidemia, obesity and diabetes, age remained a significant factor for NIH-IV prostatitis (OR = 1.35; 95% CI = 1.06-1.71; P = 0.01 and the risk of NIH-IV prostatitis was significantly higher in smokers≧15 pack/years than non-smokers (OR = 1.33; 95% CI = 1.01-1.75; P = 0.03. In addition, compared with non-drinkers, the OR of NIH-IV prostatitis in drinkers ≧1 drinks/week was 1.35 (95% CI = 1.03, 1.77, p = 0.02 after adjusting for the other variables above. In addition, having less than a college education may be a risk factor for NIH-IV prostatitis, although a statistically significant difference did not exist in our data (OR = 1.22; 95% CI = 0.97-1.52; P = 0.08. CONCLUSIONS: Our findings suggest that NIH-IV prostatitis is prevalent in China. Age, smoking, drinking and lower education levels were associated with an increased risk of NIH-IV prostatitis. The prevalence of NIH-IV prostatitis should be taken into account when estimating the total prevalence of CP in future studies.

  7. Habilidades, características pessoais, interesses e estilos de aprendizagem de adolescentes talentosos Abilities, personal characteristics, interests and learning styles of talented adolescents

    Directory of Open Access Journals (Sweden)

    Jane Farias Chagas

    2010-04-01

    Full Text Available O objetivo deste estudo foi descrever habilidades, características pessoais, interesses e estilos de aprendizagem de adolescentes talentosos. Participaram da pesquisa 42 alunos que frequentavam um programa de atendimento ao superdotado na região centro-oeste. O instrumento utilizado foi uma lista de habilidades, interesses, preferências, características e estilos de aprendizagem, elaborada para o estudo.Os adolescentes informaram apresentar um melhor desempenho associado às habilidades intrapessoal (77%, interpessoal (68% e linguístico-verbal (60%. Os resultados revelaram que os participantes percebiam-se como persistentes (84,2%, exigentes consigo mesmos (76,3%, possuidores de valores morais sólidos (76,3% e criativos (71,1%. Entre interesses e aspectos motivacionais elencados pelos adolescentes, destacaram-se: ter muitas idéias sobre muitas coisas (89,5%, ir até o fim quando buscavam atingir um objetivo (86,8%, gostar de tirar boas notas na escola (81,6%, gostar de experimentar coisas novas (78,9%. Os participantes informaram que aprendiam com mais facilidade por meio da leitura e discussão de idéias (71,1%.The purpose of this study was to describe abilities, personal characteristics, interests and learning styles of talented adolescents. Forty-two students who attended a program for the gifted in central-west region participated in the research. The instrument used was a list of abilities, interests, preferences, characteristics and learning styles, designed for the study. Adolescents have reported better performance associated with intrapersonal (77%, interpersonal (68% and linguistic-verbal (60% abilities. The results revealed that participants perceived themselves as persistent (84.2%, demanding with themselves (76.3%, owners of solid moral values (76.3% and creative (71.1%. Among interests and motivational aspects listed by the adolescents, it could be highlighted: having many ideas about many things (89.5%, going all the way

  8. Study of patients with OSAS in prethrombotic state

    Institute of Scientific and Technical Information of China (English)

    PAN Lei; XU Wenbing

    2007-01-01

    Objective:To investigate the molecular markers change of prethrombotic state in patients with obstructive sleep apnea syndrome (OSAS) and estimate the effects of nasal continuous positive airway pressure (nCPAP) therapy.Methods:To perform case-controlled study in 30 patients with OSAS and 30 healthy control group. The patients with OSAS were diagnosed by the polysomnography monitor system and treated by Auto-CPAP. Blood samples were taken and measured GMP-140, APTT, AT-Ⅲ ,PAI and t-PA. Results: As compared with the normal controls, the level of GMP-140 which reflects platelet activation was increased in patients with OSAS[(29.67±8.68)% vs (3.07±1.74)%, P<0.05)],the levels of AT-Ⅲ which reflect anticoagulation function decreased [(74.47±5.91)% vs (98.60±3.57)%,P<0.05],and the level of t-PA which reflects the activity of the fibrinolysis system decreased [(4.11±1.36)μg vs (8.65±1.22)μg,P<0.05]. The level of PAI which reflects the inhibition of the fibrinolysis increased [(107.43±8.75)% vs (89.17±4.44)%,P<0.05]. Compared to nCPAP pretherapy, GMP-140 and PAI were decreased [(17.07±7.97)% vs (29.67±8.68)%, and (95.83±5.91)% vs (107.43±8.75)%,respectively, both P<0.05], AT-Ⅲ and t-PA increased [ (95.20±6.67)% vs (74.47±5.91)%, and(5.45±1.61)μg vs (4.11±1.36)μg, respectively, both P<0.05]. The nCPAP theraphy could significantly increase the minimum arterial oxygen saturation(SaO2%) during sleep[(90.37±2.31)% vs (68.3±7.48)%,P<0.05] and significantly deseased AI,AHI and systolic blood pressure (SBP).Conclusion:Prethrombotic state is present in patients with OSAS, nCPAP theraphy can correct nocturnal hypoxaemia, partly or totally reverse prethrombotic state of patients with OSAS, decrease OSAS-related thrombotic complications.

  9. Influencia del rol de género en la conducta sexual de riesgo en adolescentes universitarios Influence of gender role on the sexual behavior of university students

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    Yesica Yolanda Rangel Flores

    2010-12-01

    Full Text Available Objetivo: Analizar el comportamiento sexual de estudiantes universitarios y la influencia del género en la caracterización del mismo. Material y métodos: Estudio transversal, descriptivo y correlacional efectuado de Enero a Junio de 2009. Muestra probabilística estratificada de 250 estudiantes de cinco programas de Licenciatura. Aplicación de instrumento creado ex profeso, validado mediante expertos y con una confiabilidad comprobada de .78 mediante Alpha de Cronbach. Estadística descriptiva e inferencial a través de SPSS 17.0. Resultados: 56.6% de la población refiere vida sexual activa, con mayor ejercicio en los hombres (x²=13.272 p=.01. Hombres más que mujeres y con una diferencia significativa refirieron tener relaciones sexuales con más de una persona en un mismo periodo de tiempo (Tb=.730 p=.000, tener encuentros sexuales casuales (Tb=.294 p=.000. La utilización del condón se refiere como habitual más en hombres (86.8% que en mujeres (50% (V=.377 p=.002. Conclusiones: Se identifican conductas de riesgo tanto en hombres como en mujeres, en ambos casos íntimamente ligados a las representaciones sociales de género.Objective: Analyze the sexual behavior of University students and the influence of gender in the characterization of the referred behavior. Material and methods: Transverse, descriptive and correlational study which was carried out from January to June 2009. Stratified probabistical sample of 250 students from five bachelor degree programs. Application of an instrument created on purpose, validated by experts with a proven reliability of .78 using Cronbach Alpha. Descriptive statistical s and inferential using SPSS 17.0. Results: 56.6% of the population referred having an active sex life, with greater exercise in men (x² = 13. 272 p =. 01. Men more than women and with a significant difference, men spoke of having sex with more than one person in a same period of time (Tb =. 730 p =. 000, having casual sexual

  10. Systematic study on surface and magnetostructural changes in Mn-substituted dysprosium ferrite by hydrothermal method

    Energy Technology Data Exchange (ETDEWEB)

    Rekha, G. [Department of Physics, College of Engineering Guindy, Anna University, Sardar Patel Road, Chennai 600025 (India); Tholkappiyan, R. [Department of Physics, College of Engineering Guindy, Anna University, Sardar Patel Road, Chennai 600025 (India); Department of Physics, College of Science, UAE University, Al-Ain 15551 (United Arab Emirates); Vishista, K., E-mail: raovishista@gmail.com [Department of Physics, College of Engineering Guindy, Anna University, Sardar Patel Road, Chennai 600025 (India); Hamed, Fathalla [Department of Physics, College of Science, UAE University, Al-Ain 15551 (United Arab Emirates)

    2016-11-01

    Highlights: • Garnet type Dy{sub 3}Fe{sub 5-x}Mn{sub x}O{sub 12} (x = 0–0.06) nanoparticles of 88.4–86.8 nm were synthesized by hydrothermal method. • The Dy, Mn, Fe and O elements in the ferrites were confirmed from XPS. • The multiple oxidation states of Fe and Mn ions, bonding energy and cationic distributions of the samples were examined by XPS. • The magnetic property shows ferromagnetic behavior from VSM technique. • The results from these studies are correlated with respect to Mn dopant. - Abstract: Dysprosium iron garnets are of scientific importance because of the wide range of magnetic properties that can be obtained in substituting dysprosium by a rare earth metal. In the present work, the effect of Mn substitution on magnetostructural changes in dysprosium ferrite nanoparticles is studied. Highly crystalline pure and Mn doped dysprosium ferrite nanoparticles were synthesized by hydrothermal method. The samples were calcined at 1100 °C for 2 h in air atmosphere which is followed by characterization using XRD, FT-IR analysis, SEM, XPS and VSM. The average crystallite size of synthesized samples were calculated by X-ray diffraction falls in the range of 88.4–86.8 nm and was found to be in cubic garnet structure. For further investigation of the structure and corresponding changes in the tetrahedral and octahedral stretching vibrational bonds, FT-IR was used. The synthesized samples consist of multiple oxidation (Fe{sup 3+} and Fe{sup 2+}) states for Fe ions and (Mn{sup 3+} and Mn{sup 2+}) Mn ions analyzed in three ways of Fe 2p and Mn 2p spectra from the XPS analysis. With respect to Mn dopant in Dy{sub 3}Fe{sub 5}O{sub 12}, the cationic distributions of elements were discussed from high resolution XPS spectra by peak position and shift, area, width. To find out the porous/void surface morphology of the sample, scanning electron microscopy was used. From XPS analysis, the presence of elements (Dy, Mn, Fe and O) and their composition in the

  11. 涤纶针织物吸汗速干整理实践及常见问题分析%Practice of Sweat Absorption and Flash Drying Finishing of Polyester Knitted Fabric and Analysis of Common Problems

    Institute of Scientific and Technical Information of China (English)

    陈庭春; 董涛涛; 李娟; 冯燕平

    2015-01-01

    The principle of sweat absorption and flash drying finishing was expounded, and polyester knitted fabrics were finished by three methods of dyeing in one bath, dipping after dyeing and padding after dyeing with sweat absorption and flash drying finishing agent PR-868EZ. The water absorption, wet permeability and flash dry-ing property and the effects on color shade and color fastness of polyester knitted fabric after different methods were tested and analyzed. The problems of sweat absorption and flash drying finishing in production were analyzed in de-tail. The results show that the water absorption, wet permeability and flash drying property of fabric after finishing by the three methods are improved obviously, but the flash drying property of fabric finished by dipping after dye-ing and padding after dyeing can not satisfy requirement when after 10 times washing; the three methods have little effects on color shade; dyeing in one bath can satisfy the color fastness requirement of common garment, dipping after dyeing and padding after dyeing have great influence on color fastness.%阐述了吸汗速干整理的原理,并选用吸汗速干整理剂PR-868EZ,通过染色同浴、染后浸渍及染后浸轧3种方法对涤纶针织面料进行整理加工. 测试并比较了不同方法整理后涤纶针织面料的吸水性、导湿性、速干性,以及对色光、色牢度的影响.详细分析了生产中常见的吸汗速干整理问题.结果表明,3种方法整理后,面料的吸水性、导湿性及速干性均能得到显著地改善,但染后浸渍及染后浸轧处理的面料,超过10次水洗,其速干性无法满足要求;3种处理方法对面料的色光影响都较小;染色同浴整理可满足常规服装色牢度要求,染后浸渍及染后浸轧整理对面料色牢度的影响较大.

  12. O sono como ativador do eletrencefalograma nos pacientes epilépticos The sleep as an activator on epileptic patient's electroencephalogram

    Directory of Open Access Journals (Sweden)

    Rosa Helena Longo

    1973-09-01

    Full Text Available Visando ao estudo da ação do sono como ativador do eletrencefalograma em pacientes epilépticos, foram estudados 1.868 pacientes com síndromes convulsivas (572 com crises generalizadas, 121 com crises temporais não psicomostras, 118 com crises psicomotoras, 410 com crises focais não temporais, 314 com crises noturnas, 165 com crises febris, 168 com crises convulsivas associadas a retardo psicomotor. Em todos os pacientes foram feitos eletrencefalogramas em vigília (repouso e hiperpnéia e durante o sono (fase lenta sendo os achados comparados. Em nosso material não encontramos diferença significativa de resposta entre o sono espontâneo e o medicamentoso. Na maioria de nossos pacientes o traçado realizado durante o sono confirmou os achados registrados em vigília. A ação ativadora do sono foi evidenciada em um número relativamente pequeno de casos, tendo atingido o seu máximo no grupo de pacientes com crises psicomotoras (26%. Nas crises generalizadas, temporais não psicomotoras, focais não temporais e noturnas o sono funcionou mais como desativador do que como ativador das anormalidades registradas em vigília.In order to study the influence of sleep on the electroencephalograms of epileptic patients the tracings obtained of 1.868 such patients were analised (572 generalized seizures; 121 non-psychomotor temporal; 118 psychomotor; 410 non-temporal focal; 314 noctural seizures; 165 febrile seizures; 168 convulsive seizures associated with psychomotor retard. The electroencephalograms were made with the patients awake (rest and hyperpnea and sleeping (slow phase, the findings being compared. There was not found any significant difference between the EEG tracings obtained during spontaneous sleep and medically induced sleep. In the majority of the cases the records obtained while the patients were asleep merely confirmed the ones made while the patients were awake. The activator action of sleep appeared only in small number of the

  13. Exigência de lisina digestível para poedeiras semipesadas de 50 a 66 semanas de idade

    Directory of Open Access Journals (Sweden)

    R.V. Nunes

    2015-12-01

    Full Text Available Com o objetivo de determinar a exigência de lisina digestível para poedeiras semipesadas no período de 50 a 66 semanas de idade, foi realizado experimento utilizando-se 150 poedeiras Shaver Brown, distribuídas em delineamento inteiramente ao acaso, com cinco tratamentos (níveis de lisina digestível: 0,79; 0,82; 0,85; 0,88 e 0,91%, seis repetições e cinco aves por unidade experimental. Foram avaliados a produção de ovos, peso médio e a massa de ovos, consumo de ração e de lisina, conversão alimentar por massa e por dúzia de ovos, gravidade específica, unidade Haugh, o índice de gema e albúmen, porcentagem de albúmen, gema e casca. O consumo de ração, a conversão alimentar por massa e dúzia de ovos, a produção, o peso e a massa de ovos não foram influenciados (P>0,05 pelos níveis de lisina digestível. Houve aumento linear no consumo de lisina (P0,05 pelos níveis de lisina digestível estudados. Os níveis de lisina influenciaram de forma quadrática (P>0,05 a unidade Haugh e o índice de albúmen, sendo estimados os níveis de 0,884 e 0,868% de lisina digestível, respectivamente. Para o índice de gema, a associação do modelo quadrático ao Linear Response Plateau (LRP estimou o nível de 0,903% de lisina digestível. Quando o objetivo é maximizar a qualidade interna dos ovos, recomenda-se o nível dietético de 0,884%, 0,868% e 0,903% de lisina digestível para unidade Haugh, índice de albúmen e índice de gema, respectivamente.

  14. 术中125I粒子植入治疗肿瘤的临床应用%The clinical application of 125I radionuclide implantation in tumor therapy

    Institute of Scientific and Technical Information of China (English)

    孙启和; 孙彬; 杨永青

    2010-01-01

    Objective To investigate the safety and clinical efficacy of permanent implantation of125I radioactive particle in the urgery of malignancies such as brain tumors,liver cancer,cholangiocarcinoma,lung cancer,prostate cancer and malignant teratoma.Methods Thirty eight patients proved by puncture biopsy,his-tology or cytology were retrospectively analyzed.Three-D images of the tumor were reconstructed using treat-ment planning system (TPS),the number and the dose rate distribution of 125I seeds were calculated.The matched eripheral dose of 125I seeds implantation was 60~120Gy,the number of 125I seeds implanted ranged from 6~40 per lesion,and the median amount of implanted 125I seeds were 23.Results Twelve months followup after the therapy showed 9 cases of complete relief,24 cases of partial relief and 5 cases of no change.The overall effective rate(complete relief+partial relief) of 12 months was 86.8%.Conclusion Permanent implantation of 125I radioactive particle in the surgery of malignancies treatment is a safe,effective treatment for tumors.%目的 探讨在手术中永久性植入125I粒子治疗脑瘤、肝癌、胆管癌、肺癌、直肠癌、前列腺癌及恶性畸胎瘤临床应用的安全性及疗效.方法 回顾性分析38例经穿刺活检、组织学或细胞学检查确诊的肿瘤患者,采用治疗计划系统(TPS)重建肿瘤的三维图像,计算出粒子植入的数量和剂量分布曲线,125I粒子治疗肿瘤处方剂量为60~120 Gy,每例植入粒子6~40颗,中位粒子数为23颗.结果 随访12个月,肿瘤完全缓解9例,部分缓解24例,无变化5例.12个月总有效率为86.8%.结论 术中植入125I粒子治疗肿瘤是一种安全、有效的方法.

  15. INVESTIGATION OF ORAL HEALTH KNOWLEDGE, BEHAVIOR OF STUDENTS IN TANG-SHAN CITY%唐山市大学生口腔健康知识、行为抽样调查

    Institute of Scientific and Technical Information of China (English)

    赵艳萍; 董伟; 陈乃玲

    2012-01-01

    [目的]了解唐山市大学生的口腔健康知识和健康行为,为高校开展口腔健康课程提供参考资料.[方法]对唐山市4所高校1 011名大学生进行口腔健康知识和行为的问卷调查.[结果]唐山市大学生口腔健康的一般性知识知晓率和口腔卫生措施实施率较高,但对龋病和牙周病的防治知识欠缺,定期口腔检查,洁牙的意识薄弱,口腔疾病发生时就医率普遍较低,多教学生在遇到口腔疾病后就医意识淡漠.86.8%从未洁过牙,牙线和含氟牙膏的使用者也相当少.[结论]唐山市大学生对口腔健康知识认知不足,口腔健康行为有待改进,在高校开展口腔健康教育十分必要.%[Objective] To provide reference for colleges to develop oral health curriculum, to investigate the oral health knowledge, behavior among college students in Tangshan [Methods] One thousand and eleven students from colleges in Tang-sban were investigated by questionnaires. [Results] College students' general knowledge on oral health was rich, but their o-ral professional knowledge was limited which included dental caries, periodontal disease prevention. The consciousness about the oral examination and teeth cleaning on a regular basis was weak. Even if they had some disease of oral cavity, they vrouldn' t go to see doctors in time; 86.8% of the college students had never accepted the professional cleaning and the usage rate of the dental floss and toothpaste with fluorine were low. [Conclusion] The oral knowledge of students in Tangshan is poor and the situation is also bad. It is rather necessary to develop oral health curriculum in colleges.

  16. Níveis de metionina + cistina para frangos de corte de 1 a 21 e 22 a 42 dias de idade Methionine + cystine levels for broilers from 1 to 21 and from 22 to 42 days of age

    Directory of Open Access Journals (Sweden)

    Luiz Fernando Teixeira Albino

    1999-01-01

    Full Text Available Este experimento foi realizado para determinar a exigência nutricional em metionina + cistina (aminoácidos sulfurosos para frangos de corte Hubbard e Ross de ambos os sexos, no período de 1 a 21 e 22 a 42 dias de idade. Ganho de peso, consumo, conversão alimentar e composição de carcaça das aves foram avaliados. Foram usadas 2400 aves na fase de 1 a 21 dias de idade e 1800 na fase de 22 a 42 dias de idade. Rações basais com 21e 19% PB e 3000 e 3100 kcal EM/kg foram suplementadas com seis níveis de metionina + cistina ( 0; 0,06; 0,12; 0,18; 0,24; e 0,30 nas fases de 1 a 21 e 22 a 42 dias de idade, respectivamente. As estimativas das exigências de metionina + cistina para a fase de 1 a 21 dias foram 0,886 e 0,896% e 0,890 e 0,868% e para a fase de 22 a 42 dias, 0,795 e 0,802% e 0,810 e 0,792%, para machos e fêmeas Hubbard e Ross, respectivamente.This experiment was carried out to determine the nutritional requirement of methionine + cystine (sulfur amino acids for Hubbard and Ross broilers from 1 to 21 and from 22 to 42 days of age, of both sexes. Weight gain, intake, feed:gain and carcass composition were evaluated. Two thousand and four hundred broilers were used in the phase from 1 to 21 of age and 1800 broilers in the phase from 22 a 42 days of age. Basal diets with 21 and 19% of the CP and 3000 and 3100 kcal ME/kg were supplemented with six levels of methionine + cystine in the phases from 1 to 21 and from 22 to 42 of age, respectively. The estimated requirements of methionine + cystine ( 0; .06; .12; .18; .24; and .30 for the phase from 1 to 21 days were. 886% and .896%, .890% and .868% and for the phase from 22 to 42 days, .795%, and .802%, .810% and .792% for Hubbard and Ross male and female, respectively.

  17. 抗核抗体谱检测在诊断系统性红斑狼疮中的意义%Clinical Significance of Anti-nuclear Antibodies Detection in the Diagnosis of Systemic Lupus Erythematosus

    Institute of Scientific and Technical Information of China (English)

    蒋素莹; 卢永芳; 谢丹萍; 张金珍

    2013-01-01

    探讨抗核抗体(ANA)和抗核抗体谱(ANAs)检测对诊断系统性红斑狼疮(SLE)患者的临床意义.用间接免疫荧光法(IIF)和免疫印迹法检测106例SLE组和30名对照组血清ANA及ANAs中的12种抗体.结果表明:SLE组ANA阳性率为86.8%,ANAs中抗ds-DNA、抗Scl-70、抗Jo-1、抗nRNP、抗Sm、抗SS-A、抗SS-B、抗Ro-52、抗CENP-B、抗AnuA、抗AHA和抗核糖体P蛋白的阳性率分别为28.3%、0.9%、0.9%、35.9%、17.0%、39.6%、18.9%、41.5%、9.4%、29.3%、31.1%和9.4%.ANA和ANAs联合检测提高了诊断的敏感性,对SLE的诊断和治疗有重要意义.%Objective To explore the clinical significance of anti-nuclear antibody (ANA) detection in the diagnosis of systemic lupus erythematosus (SLE) patients.Methods The serum ANA and anti-nuclear antibody spectrum (ANAs) of 12 kinds of antibodies in 106 SLE patients and 30 healthy control group were detected by indirect immunofluorescence assay (IIF) and western blot detection.Results The results showed that the positive rate of ANA was 86.8% in SLE patients,and positive rates of ANAs in anti-ds-DNA,anti-Scl-70、antiJo-1 、anti-nRNP,anti-Sm,anti-SS-A,anti-SS-B,anti-Ro-52,anti-CENP-B,anti-AnuA,anti-AHA and the ribosomal P-protien were 28.3%,0.9%,0.9%,35.9%,17.0%,39.6%,18.9%,41.5%,9.4%,29.3%,31.1% and 9.4%,respectively.Conclusion The combined detection of ANA and ANAs could improve the sensitivity and have important significance in the diagnosis and treatment of SLE.

  18. Phylogenetic assessment of a new cypermethrin- degrading bacterium Gordonia sp.D2 based on 16S rDNA, gyrB and GyrB sequences%一株氯氰菊酯降解菌16S rDNA,gyrB和GyrB的系统发育分析

    Institute of Scientific and Technical Information of China (English)

    张久刚; 闫艳春

    2008-01-01

    A cypermethrin - degrading bacterium named as Gordonia sp. D2 was isolated from activated sludge of a wastewater treatment biore-actor. At 30 ℃ and pH 7.0, the removal rate of 100 mg cypennethrin L-1 was approximately 52.3% in mineral salts medium within 7.5 days, and extra carbon source addition could enhance the biodegradation. The isolate was identified as Gordonia genus through physio - bio- chemical identification combined with the phylogenetic analyses based on 16S rRNA, gyrB nucleotide and GyrB amino acid sequences. 16S rRNA sequences of strain D2 showed the highest similarity to G. amicalis DSM44461 and G. hydrophobica DSM44015T, with the same value of 98.1% ,meanwhile, D2 shows the highest similarity to G. hydrophobica JCA10086 with the value of 86.8% and 91.1% based on gyrB and GyrB. Three phylogenetic dendrograms were made, and results showed that 16S rRNA gene is suit for identifying the isolate to the genus level, gyrB gene and GyrB amino acid sequences are more adapted for phylogenetic analysis.%从农药厂污水处理池中分离得到一株氯氰菊酯降解菌,在30℃,pH 7.0的条件下,无机盐培养基中100mg/L的氯氰菊酯,经过7.5天,能够降解大约52.3%,外加碳源能够明显提高其降解性能.生理生化实验结合16S rDNA,gyrB和GyrB的系统发育分析,将其归为Gordonia菌属.在16S rDNA水平上,其与G.amicalis DSM44461和G.hydrophobica DSM44015的相似值最高,为98.1%;而在gyrB和GyrB水平上,其与G.hydrophobica JCM10086的相似值最高,分别为86.8%和91.1%.通过对所构建的系统发育树进行评估,表明16S rDNA序列适用于将分离菌株鉴定到属的水平上,而gyrB和GyrB更适用于在属内种的水平上进行系统发育的分析.

  19. Differential Diagnosis Value of Pleural Fluid ADA and CEA Detection for Tuberculous Pleuritis and Carcinomatous Pleuritis%胸水ADA、CEA检测在结核性与癌性胸膜炎鉴别诊断中的价值

    Institute of Scientific and Technical Information of China (English)

    许能銮; 李瑞慧; 陈愉生; 林章树

    2007-01-01

    [目的]探讨胸水腺苷脱氨酶(ADA)和癌胚抗原(CEA)检测在结核性胸膜炎与癌性胸膜炎鉴别诊断中的价值.[方法]选择38例结核性胸膜炎和42例癌性胸膜炎住院患者,用速率法检测胸水ADA活性,电化学发光免疫法检测胸水CEA,评价二者诊断的真实性、预测值和似然比.[结果]结核性胸膜炎组ADA阳性率86.8%高于癌性胸膜炎组的2.4%(P<0.01);癌性胸膜炎组CEA阳性率71.4%高于结核性胸膜炎组的2.6%(P<0.01).ADA诊断结核性胸膜炎的敏感性为86.8%、特异性97.6%、正确诊断(约登)指数(Yoden's index)0.84、阳性预测值97.1%、阴性预测值89.1%、阳性似然比36.49、阴性似然比0.14;CEA诊断癌性胸膜炎的敏感性71.4%、特异性97.4%、约登指数0.84、阳性预测值96.8%、阴性预测值75.51%、阳性似然比27.16、阴性似然比为0.29.[结论]检测胸水ADA、CEA在结核性胸膜炎与癌性胸膜炎鉴别诊断中有重要的临床意义.

  20. 高职高专护理专业毕业生就业情况调查与分析%Investigation and Analysis on the Employment Situation of Nursing Students Accepted Higher Technical and Vocational Education

    Institute of Scientific and Technical Information of China (English)

    孔祥照; 徐建平; 冯萍芳

    2014-01-01

    为了对学生进行准确的专业定位,更好地开展就业指导提供依据,本文收集了北京市某学院707名高职高专护理专业毕业生的就业信息,对其就业情况进行调查和分析。毕业生生源地为郊区、县的为86.8%,城八区为13.2%;总体就业率为99.89%,专业对口率为98.0%;92.5%的学生毕业时签<在三级综合性医院;专升本为0.7%。结果表明,毕业生生源地以郊区、县为主;就业率和专业对口率都较高;毕业生主要工作在北京市三级综合医院;毕业时选择继续深造的比例很小。%To know the employment situation of nursing students accepted higher technical and vocational education,and provide the basis for the accurate professional positioning and career guidance,707 nursing students are col ected. The rate of students from the suburban districts and counties is 86.8%,while the eight urban districts is 13.2%;the average employment rate is 99.89%,and job suited rate is 98.0%;92.5% of nursing students work at the front-line in general hospitals that are third-class; and the rate of students admit ed to the undergraduate is only 0.7%. Nursing graduates accepted higher technical and vocational education are mainly from the suburban districts and counties in Beijing. The employment rate and job suited rate are high. The students' position is in general hospitals that are third-class. The students who choose to continue their studies are rare.

  1. PENGARUH KETERAMPILAN MENGAJAR GURU, DISIPLIN BELAJAR DAN SIKAP SISWA TERHADAP MOTIVASI BELAJAR MATA DIKLAT BEKERJASAMA DENGAN KOLEGA DAN PELANGGAN PADA SISWA KELAS X PROGRAM KEAHLIAN ADMINISTRASI PERKANTORAN DI SMK PL TARCISIUS 1 SEMARANG

    Directory of Open Access Journals (Sweden)

    Parastining Mulyany

    2013-11-01

    Full Text Available Tujuan penelitian ini adalah: (1 Untuk mengetahui keterampilan mengajar guru, disiplin belajar dan sikap siswa terhadap motivasi belajar (2 Untuk mengetahui ada tidaknya pengaruh keterampilan mengajar guru, disiplin belajar dan sikap siswa terhadap motivasi belajar. Populasi penelitian ini adalah siswa kelas X Program Keahlian Administrasi Perkantoran SMK PL Tarcisius 1 Semarang yang berjumlah 110 siswa. Metode pengumpulan data menggunakan kuesioner dan dokumentasi. Analisis data menggunakan analisis regresi berganda. Hasil penelitian menunjukkan bahwa analisis regresi linear berganda diperoleh persamaan: Y = 2,241 + 0,034 X1 + 0,419 X2 + 0,594 X3 Uji F diperoleh Fhitung33,753, sehingga H4 diterima. Secara parsial (uji t variabel keterampilan mengajar guru (X1 diperoleh thitung = 0,407, sehingga H1 ditolak. Variabel disiplin belajar (X2 diperoleh thitung = 3.272, sehingga H2 diterima. Variabel sikap siswa (X3 diperoleh thitung = 5.868, sehingga H3 diterima. Secara simultan (R2 keterampilan mengajar guru, disiplin belajar dan sikap siswa berpengaruh terhadap motivasi belajar sebesar 47,4%. The aim problems of this study were : (1 the teaching skills, the students’ learning discipline, the students’ attitudes, and the students’ motivation. (2 the effects of the teaching skills, the students’ learning discipline, and the students’ attitudes on the students’ motivation. The population of this study were the tenth grade students of Office Administration Program of SMK PL Tarcisius 1 Semarang which consisted of 110 students. The data were collected by questionnaires and documentations. The data then, were analyzed by multiple regression analysis. The results of the study showed that the multiple linear regression analysis, it was gained an equation Ŷ = 2.241 + 0.034 X1 + 0.419 X2 + 0.594 X3. The Fvalue obtained from F-test was 33.753 so that H4 was accepted. Partially (t-test, the tvalue for the teachers’ teaching skills variable (X1

  2. 老年高血压病患者焦虑抑郁症状的临床特征与治疗%The clinical characteristics and treatment of senile hypertension patients with symptoms of anxiety and depression

    Institute of Scientific and Technical Information of China (English)

    严臻

    2014-01-01

    Objective to determine the clinical feature and therapy of the aged with hypertention and anxiety disorder and depressive disorder. Methods 148 patients with hypertention were assessed by Hamilton anxiety scale (HaMa) and hamilton rating scale for depression (HaMd).the patients with anxiety disorder and depressive disorder accepted ssri and mental intervention, HaMa and HaMd were assessed immediately at 3,6 and 9 weeks after treatment. Results among the 148 patients, the incidence rate of anxiety disorder was 33.1%, depressive disorder was 25.6%. their improvement rates were 83.6% and 86.8%. The Hamilton anxiety scale and the hamilton rating scale for depression were significantly improved at 3 weeks after treatment, especially at 6 and 9 weeks. Conclusion there were higher incidencerate in the aged with hypertention and anxiety disorder and depressive disorder. There were significant the rapeutic effect by antianxiety the rapy and related to the rapeutic time.%目的:探讨老年高血压病患者焦虑抑郁症状的临床特征及治疗。方法应用心理测试量表(HaMa 和 HaMd)评估148例老年高血压病患者,对伴有焦虑抑郁症状的患者,给予赛乐特(ssri)治疗同时给予不同心理治疗方法进行心理干预,在治疗后3w、6w、9w 再进行评分。结果148例患者中,焦虑、抑郁性障碍的发生率分别为33.1%、25.6%,治疗好转率分别为83.6%、86.8%。治疗后3w 时 HaMa 和 HaMd 积分较治疗前明显减少,并以6w、9w 最为显著。结论焦虑抑郁性障碍在老年高血压病患者中的发生率较高,抗焦虑抑郁治疗的疗效显著,并与用药(相关治疗)时间有关。

  3. Evaluación del rendimiento de tesauros españoles en sistemas de recuperación de información

    Directory of Open Access Journals (Sweden)

    Gil Urdiciain, B.

    1998-09-01

    Full Text Available The article describes an experimental test developed in Spanish databases. The test compares the performance between different thesauri and the natural language, in the process of information retrieval. The test was carried out with the combination of the analytic and sampling methods. The searches were made interactively, the records were evaluated, and the search strategies modified based on the parcial results. The references obtained with each kind of language were evaluated on the basis of the precision and recall ratios. The results point out that free text obtained a precision ratio of 63.4 % and a recall of 59.5 %; with the help of the thesauri both ratios improved: the precision reached a 86.8 % and the recall a 61.6 %. The conclusion is that the controlled vocabulary experiences lower levels of noise than the free text, at the same time it can develop high ratios of recall as the controlled one. Also, it is possible to conclude that the controlled vocabulary neutralizes the deficiences of the free text and vice versa, so both are complementary.

    El artículo describe un estudio experimental desarrollado en bases de datos españolas en el que se establece la comparación del rendimiento entre diferentes tesauros y el lenguaje natural, en el proceso de recuperación de la información. El test se llevó a cabo mediante la combinación de los métodos analítico y de muestreo y validación de datos. Las consultas se realizaron de modo interactivo, evaluándose los registros y modificándose las estrategias a la vista de los resultados. Las referencias recuperadas en cada modalidad se valoraron en base a las tasas de precisión y exhaustividad. Los resultados muestran que en lenguaje libre se consiguió una precisión del 63,4 % y una exhaustividad del 59,5 %; con la ayuda del tesauro ambos índices mejoraron: en precisión se alcanzó un 86,8 % y en exhaustividad un 61,6 %. Se concluye que el lenguaje controlado consigue más bajos

  4. HPLC 法测定小儿氨酚黄那敏颗粒中阿斯帕坦的含量%Determination of Aspartame in Xiaoer Anfen Huang Namin Granule by HPLC

    Institute of Scientific and Technical Information of China (English)

    孙菲

    2016-01-01

    目的:建立小儿氨酚黄那敏颗粒中阿斯帕坦的高效液相色谱测定方法。方法:采用 AgiLent Zorbax SB-C18(250 mm ×4.6 mm,5μm)色谱柱,以乙腈-0.05 mol·L -1磷酸(20∶80)为流动相,流速为1.0 ml·min-1,检测波长为204 nm,柱温为25℃,进样量为10μl。结果:阿斯帕坦在21.72~868.67μg·ml -1浓度范围内呈良好的线性关系(r =1.0000),平均回收率为99.36%(RSD =0.3%,n =6)。结论:该方法稳定性和重复性均较好,可用于测定小儿氨酚黄那敏颗粒的质量控制。%Objective:To establish an HPLC method for the determination of aspartame in Xiaoer Anfen Huang Namin granule. Methods:An Agilent Zorbax SB-C18 column(250 mm × 4. 6 mm,5 μm)was used with the mobile phase of acetonitrile-0. 05 mol·L -1 H3 PO4(20 ∶80). The flow rate was 1. 0 ml ·min -1 and the detection wavelength was 204 nm. The column temperature was 25℃ and the injection volume was 10 μl. Results:Aspartame had a good linear relationship within the range of 21. 72- 868. 67 μg · ml -1(r = 1. 000 0). The average recovery of aspartame was 99. 36% and RSD was 0. 3% (n = 6). Conclusion:The method has good stability and repeatability,and is suitable for the quality control of Xiaoer Anfen Huang Namin granule.

  5. 基于混合熵和L_1范数的遥感图像分类%Remote sensing image classification based on hybrid entropy and L1 norm

    Institute of Scientific and Technical Information of China (English)

    王雪松; 高阳; 程玉虎; 汪婵

    2012-01-01

    Aiming at remote sensing image data having properties of high-dimension, nonlinearity, and massive unlabeled samples, a kind of probability least squares support vector machine (PLSSVM) classification method based on hybrid entroy and Ll-norm was proposed. At first, a hybrid entroy was designed by combining quasi-entropy with entropy difference, which was used to select the most 'valuable' unlabeled samples from the massive unlabeled sample set. In the second step, a L~-norm distance mectric was used to further select and to remove outliers and redundant data from the most 'valuable' unlabeled samples. At last, the original labeled and the selected unlabeled samples were adopted to train the PLSSVM. Experimental results on ROSIS hyperspectral remote sensing image show that the overall accuracy and Kappa coeffi- cient of the proposed classification method reach 89.90% and 0. 868 5 respectively. The pro- posed method can obtain higher classification accuracy with few training samples, which is much applicable for classification problem of remote sensing image.%针对遥感图像数据具有的高维数、非线性以及海量无标记样本的特性,提出了一种基于混合熵和L1范数的概率型最小二乘支持向量机分类方法.将准熵和熵差分融合,构造一种混合熵用以从海量无标记样本集中选出最有"价值"的待标记样本;基于L1范数距离度量,进一步从待标记样本集中筛选出孤立点和冗余点加以剔除;基于初始已标记样本以及筛选得到的样本,训练得到概率型最小二乘支持向量机.对反射光学系统的成像光谱仪(ROSIS)高光谱遥感图像进行了分类实验.结果表明:所提分类方法的总精度和Kappa系数分别达到了89.90%和0.868 5,能够以较少的训练样本得到较高的分类精度,其更适于处理遥感图像分类问题.

  6. The diet of the fox (Vulpes vulpes in woodlands of Orobie Alps (Lombardy region, Northern Italy / Alimentazione della Volpe (Vulpes vulpes in aree boscate delle Alpi Orobie

    Directory of Open Access Journals (Sweden)

    Marco Cantini

    1991-07-01

    Full Text Available Abstract The diet of the fox was investigated by analysis of 273 scats, collected along standard trails from April to November 1987 and 1988. Food habits of foxes were described for three altitudinal ranges. Mammals, mainly Clethrionomys glareolus and Microtus multiplex, were the staple food (percentage of frequency 42.8%, followed by fruits and other vegetables (26.7% and 37.3% respectively. Birds, Invertebrates (mainly Insects and garbage were little eaten. The game species (ungulates, hares, pheasants occurred with a low frequency (8.4% in the diet. The trophic niche breadth varied little through the altitudinal ranges and the seasons. The trophic niche overlap between the fox and the genus Martes (190 scats of M. martes and M. foina were examined is relatively wide (O=0.868. Riassunto La dieta della Volpe (Vulpes vulpes in aree boscate delle Alpi Orobie (Val Lesina è stata indagata nel periodo aprile-novembre 1987 e 1988 mediante l'analisi di 273 feci, raccolte lungo percorsi-campione ricadenti in tre piani vegetazionali. I Mammiferi, in particolare Clethrionomys glareolus e Microtus multiplex, sono la componente principale della dieta (frequenza percentuale 42,8%. Rilevante è anche il consumo di frutti (soprattutto in estate e autunno e di altri vegetali (26,7% e 37,3% rispettivamente, mentre poco frequente è quello di Uccelli, Invertebrati e rifiuti. Complessivamente ridotta è l'azione predatoria della Volpe nei confronti delle specie di interesse venatorio (Ungulati, lepri, Galliformi. L'ampiezza della nicchia trofica mostra modeste variazioni stagionali e altitudinali. I1 grado di sovrapposizione tra la nicchia trofica della Volpe e quella del genere Martes, quest'ultima ricavata dall'analisi di 190 feci di Martora (M. martes e Faina (M. foina, è elevato (O=0,868. Tuttavia, poiché in condizioni di

  7. 不同杀菌剂对马铃薯疮痂病的防效试验%Control Efficacy of Various Fungicides on Potato Common Scab

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    张建平; 哈斯; 林团荣; 尹玉和; 郑友; 闫任沛; 程玉臣; 胡冰

    2013-01-01

    At present, the potato common scab (Streptomyces spp.) is one of the important diseases in potato production in Inner Mongolia. It is also one of the most serious problems in minituber production. No effective fungicide available is the main factor for the severity of potato common scab. In this research, vermiculite was treated with ten fungicides in plot experiments in 2012 to control potato common scab in net covered shed. The results indicated the control efficacy of Chuangjiazhi 200 times dilution, 99%Copper Sulfate 40 times dilution, 50%Captan WP 500 times dilution, 77%Copper Hydroxide WP 500 times dilution and 80%Mancozeb WP 500 times dilution was, respectively, 86.8%, 55.1%, 50.9%, 42.9%and 41.2%. The Chaungjiazhi 200 times dilution had excel ent effects for control of potato common scab.%  马铃薯疮痂病(Streptomyces spp.)是目前内蒙古马铃薯生产的重要病害之一,更是影响微型薯生产的主要病害。缺少有效杀菌剂是病害严重的主要原因,2012年选用10种杀菌剂进行了网棚蛭石消毒防治该病害试验。结果表明:疮痂治200倍液防效86.8%,99%硫酸铜40倍液防效55.1%、50%克菌丹可湿性粉剂500倍液防效50.9%、77%冠菌铜可湿性粉剂500倍液防效42.9%、80%代森锰锌可湿性粉剂500倍液防效41.2%。疮痂治对防治马铃薯疮痂病具有优越效果。

  8. SBR法后续处理垃圾渗滤液的影响因素%The Impact Factors of Subsequent Treatment on Landfill Leachate by SBR Process

    Institute of Scientific and Technical Information of China (English)

    王杰; 马溪平; 郑旭; 陈忠林; 庞香蕊

    2011-01-01

    为提高垃圾渗滤液处理效果,采用序批式活性污泥法(SBR)对垃圾渗滤液进行后续处理,考察了曝气时间、污泥浓度、沉降时间和pH对SBR工艺的影响.结果表明:经过30 d污泥培养驯化,测得SVIvi=80~100,SV30<0.3,MLSS=2.8~3.0/L,镜检可见大量钟虫、轮虫和原生动物等;在曝气时间8h,污泥浓度3.5g/L,沉降时间2.5h,pH=7的条件下使垃圾渗滤液中COD由1600 g/L下降到 352mg/L,NH3-N由485mg/L下降到86.8mg/L,SS由260mg/L下降到52 mg/L,去除率分别达到78%,82.1%和80%.%In order to improve the effects of treatment on landfill leachate, a sequencing batch reactor (SBR) processs was used to dispose the leachate which had been pre-treated by catalytic oxidation assisted with microwave.The results show that the sludge is mature after thirty days' s cultivation and domestication, and SVI is 80 ~ 100,SV30 < 0.3, MLSS is 2.8 ~ 3.0 g/L,a large number of vorticella,rotifer and protozoa are observed under microscope; when aeration time is 8 h,sludge concentration is 3.5 g/L,sedimentation time is 2.5 h, pH = 7, the COD is reduced from 1 600 mg/L to 352 mg/L,NH3-N is reduced from 485 mg/L to 86.8 mg/L, SS is reduced from 260 mg/L to 52 mg/L, the disposal rates attain 78% ,82.1% and 80% respectively.

  9. Efficiency of Several Fungicides to Control Wheat Powdery Mildew%几种杀菌剂对小麦白粉病的防治效果

    Institute of Scientific and Technical Information of China (English)

    杨共强; 宋玉立; 何文兰; 孙静

    2011-01-01

    为了筛选对小麦白粉病有效的防治药剂,在小麦白粉病发病初期,选用7.5%氟环唑乳油、50%醚菌酯干悬浮剂等13种杀菌剂进行喷雾,25d后调查发病情况.结果表明,13种杀菌剂对小麦白粉病均有一定的防效,为40.5%~86.8%.其中50%醚菌酯干悬浮剂、7.5%氟环唑乳油、25%丙环唑乳油3种药剂对小麦白粉病的防效最好,分别为86.8%、85.1%、79.3%其次为50%禾瑞水分散粒剂、5%烯肟菌胺乳油、12.5%烯唑醇可湿性粉剂、15%氯啶菌酯乳油、20%戊唑醇·烯肟菌胺悬浮剂和15%三唑酮可湿性粉剂6种药剂,防效在60.8%~69.3%.以上9种药剂对小麦白粉病有较好的防治效果,可在生产上推广应用.%In order to screen effective fungicides to control wheat powdery mildew, the efficacy of 13 fungicides was measured against wheat powdery mildew in the fields. The fungicides were spayed at the early stage of the disease and the disease condition was investigated after 25 days. The results showed that 13 fungicides had some control effects of 40. 5%-86. 8%. Three fungicides, 50% Kresoxim-methyl DF,7. 5% Epoxiconazole EC and 25% Propiconazole EC had best control effect (86. 8%, 85. 1% and 79. 3%, respectively), and the other six fungicides, 50% Cyprodinil WG, 5% SYP-1620 EC,12. 5% Diniconazole WP,15% SYP-7017 EC, 20% Tebuconazole ~ SYP-1620 SC and 15% Triadimefon WP also had good control effect (69. 3%, 66. 7%, 65.0%, 63. 6%, 62. 4% and 60. 8% .respectively). The nine fungicides were recommended for use in wheat production.

  10. Construction Technology of Two-Dragon Crape Myrtle Theme Park in Shaoyang City%邵阳市双龙紫薇主题公园营建技术

    Institute of Scientific and Technical Information of China (English)

    黄建民; 侯伯鑫

    2012-01-01

    湖南省内首个由民营企业投资建设的公益性城市主题公园面积68hm2,利用邵阳市区一处紫色页岩荒山建成,历时10年,投资2亿元,采用破岩换土等高标准工程造林技术,以紫薇双龙大型植物园艺造景为主体,采取乔、灌、草、水景等立体建园模式。园内紫薇造景龙单条全长868m、宽3.75m、高2.80m,龙头长20.65m、高7.70m,造型所用紫薇总株数1909株。目前正申请世界上最长、最大的植物园艺造型作品吉尼斯世界纪录。%The first public urban theme park covers an area of 68 hm2 that was constructed by private enterprise in Hunan Province after 10 years with the investment of 200 million yuan. The park was constructed under the vertical pattern combining arbor, shrub, grass and water bodies by utilizing a purple shale wasteland in Shaoyang City, by a- dopting high-standard engineering forestation technology such as breaking rock for soil and by making large-scaled two- dragon crape myrtle plant modeling as file main body. One of the crape myrtle dragons in the park was 868 m long, 3.75 m wide and 2. 80 m high, and its head was 20. 65 m long and 7. 70 m high. This dragon was molded with 1909 crape myrtle trees. The park is now applying for the Guinness World Records for the world longest and largest horti- cultural plant modeling.

  11. 中医院急诊科护士团队效能的调查分析%Survey and Analysis of Nurses' Team Efficacy of Emergency Department in Chinese Medicine Hospital

    Institute of Scientific and Technical Information of China (English)

    谭益冰; 江淑聘

    2014-01-01

    Objective To know the level of nurses' team efficacy of emergency department in Chinese medicine hospital and explore its affected factors. Methods Cluster sampling was used, and general data questionnaire and team efficiency scale were used. Results 102 subjects were recruited, the total score of team efficacy was 4.34±0.73, belonged to 86.8%level;The differences in several groups, such as age (F = 7.18, P <0.05), working time (F = 2.93, P <0.05) and working department (t = 4.39, P <0.05) were statistically significant. Conclusions Nurses of emergency department in Chinese medicine have good team efficiency, especially in team work efficiency and responsibility. The team efficacy of nurses in middle class and who haven't been fixed up to certain department should be strengthened.%目的:了解中医院急诊科护士团队效能的水平,探讨其影响因素。方法采用整群抽样,使用一般资料调查表及《团队效能量表》对广州市某两家三甲中医院急诊科护士进行调查。结果共调查102人,中医院急诊科护士团队效能总分(4.34±0.73)分,水平为86.8%;不同年龄(F=7.18,P<0.05)、工作时间(F=2.93,P<0.05)及定科情况(t=4.39,P<0.05)组的总分差异具有统计学意义。结论中医院急诊科护士具有良好的团队效能,体现在团队工作效率与责任感;需加强“夹心层”及未定科护士的团队效能。

  12. 直接RT-LAMP检测EV71方法的建立和评价%Development and assessment of direct reverse transcription loop-mediated isothermal amplification for EV71 detection

    Institute of Scientific and Technical Information of China (English)

    阮美生; 郭龙华; 周天龙; 黎荣

    2015-01-01

    Objective To develop a simple and rapid direct reverse transcription loop-mediated isothermal am-plification (direct RT-LAMP) experimental method for detecting enterovirus 71 (EV71) infection, and the sensitivity and specificity of this method using clinical nasopharyngeal swab specimens for the detection of EV71 were evaluated. Methods Direct RT-LAMP without RNA extraction and with heat-treatment was used to detect EV71 infection in 290 nasopharyngeal swab specimens. The sensitivity and specificity were evaluated. Results The accordance rate of direct RT-LAMP and RT-LAMP was 92.4%(268/290), and that of direct RT-LAMP and qRT-PCR was 88.9%. No false posi-tive was found in direct RT-LAMP or RT-LAMP. The clinical performance demonstrated the sensitivity and specificity of direct RT-LAMP was 90.3%and 100%compared to RT-LAMP, and 86.8%and 100%compared to qRT-PCR, re-spectively. Conclusion Direct RT-LAMP method can potentially be developed for simple and rapid screening of EV71 and other pathogens.%目的:建立并评价一种简单快速的逆转录环-介导的等温扩增(直接RT-LAMP)检测人肠道病毒71(EV71)的实验方法。方法无需RNA提取,用热处理标本后用直接RT-LAMP方法检测EV71,并用临床收集的290份咽试标本评价其灵敏度和特异性。结果直接RT-LAMP和RT-LAMP实验完全符合率为92.4%(268/290),直接RT-LAMP和qRT-PCR完全符合率为88.9%。在RT-LAMP或直接RT-LAMP实验中没有发现假阳性。与RT-LAMP比较,直接RT-LAMP的灵敏度和特异性分别为90.3%和100%;与qRT-PCR比较,其敏感性和特异性分别为86.8%和100%。结论直接RT-LAMP方法能被开发成简单快速检测EV71和其他病原体的方法。

  13. 反相高效液相色谱法测定甜叶菊中A苷甜菊糖和甜菊苷含量%Determination of Content of Rebaudioside A and Stevioside in Steviarebaudiana Bertoni by RP-HPLC

    Institute of Scientific and Technical Information of China (English)

    邹盛勤; 姜琼

    2014-01-01

    采用超声辅助提取,建立甜叶菊中A苷甜菊糖和甜菊苷的高效液相色谱分析方法。采用 Kroma-sil C18(4.6 mm×250 mm,5μm)色谱柱,以甲醇∶水(75∶25,V/V)为流动相,流速1.0 mL/min,检测波长210 nm,柱温30℃。A苷甜菊糖进样量在0.868~8.68μg时,与峰面积呈良好的线性关系(R=0.999),平均回收率为97.5%,RSD为1.8%(n=6);甜菊苷进样量在1.004~10.04μg时,与峰面积呈良好的线性关系(R=0.999),平均回收率为95.6%,RSD为1.6%(n=6)。该方法准确、操作简便,可用于甜叶菊中A苷甜菊糖和甜菊苷含量测定。%HPLC method for the determination of rebaudioside A and stevioside in Stevia rebaudiana Bertoni is established by ultrasonic assisted extraction method.The separation is achieved on a Kro-masil C18 column (4.6 mm×250 mm,5μm)at 30 ℃ using methanol and water solution (75∶25, V/V)as the mobile phase at a flow rate of 1 .0 mL/min,2 1 0 nm as the detection wavelength.Rebau-dioside A shows good relationship at the range of 0.868~8.68μg (R=0.999),the recovery is 97.5%and RSD is 1.8% (n=6).Stevioside shows a good relationship at the range of 1.004~10.04μg (R=0.999),the recovery is 95.6% and RSD is 1.6% (n=6).The proposed method is accurate,simple and applicable for the determination of rebaudioside A and stevioside in Stevia rebaudiana Berton.

  14. 不同嫁接时间和砧木处理对薄壳山核桃嫁接成活率的影响%Effects of Grafting Time and Grafting Methods on the Survival Rate of Carya illinoensis

    Institute of Scientific and Technical Information of China (English)

    赵伟明; 张海军; 施娟娟; 杨先裕; 袁紫倩; 王正加

    2014-01-01

    Choose 1-year-old Carya illinoensis seedling as rootstock and applied cut-grafting method,to study the effects of the grafting time and 3 treatments (transplanting grafts,root pruning cut grafts and not root pruning cut grafts)on survival rate and the growth of shoots.The results showed that:after grafting,the survival rate of 3 treatments appeared a peak at April 8 th .Among of them,the survival rate of transplanting grafts was the highest which was 86.8%.From 28 th May to 28 th July,the survival rate of the three treatments was basically equal (33%-48.6%).The crude and high growth of new branchs was positive correlated to the rootstock’s diameter.%以薄壳核桃1年生大小均匀的实生苗作为砧木,通过移栽、断根和不断根3种处理方式,采用切接法,在不同时间对薄壳山核桃进行嫁接,研究嫁接时间和砧木不同处理方式对嫁接成活率及新梢生长状况的影响。结果表明:4月8号3种砧木处理方式嫁接成活率均出现峰值,其中移栽切接的成活率最高,为86.8%,5月28号到7月28号3种砧木处理方法嫁接成活率基本相同,为33.0%~46.7%。砧木的粗度与新梢的粗生长与高生长之间存在正相关关系。

  15. Setting efficiency indicators for center pivots Ajuste de indicadores de eficiência para pivôs centrais

    Directory of Open Access Journals (Sweden)

    Ricardo L. Schons

    2012-06-01

    Full Text Available In this study, it was discussed the efficiency criteria in each of the elements that compose a central pivot, and this analysis was applied to two sets of systems located in regions of Cruz Alta and Santo Augusto, state of Rio Grande do Sul, Brazil. The methodology used combines water and energy assessment through an indicator called Normalized Specific Consumption in Irrigation (C ENI, allowing thus a comparison between equipment and projects. The C ENI in Cruz Alta region showed 72% of the equipment above the standard (8.68 kWh mm-1 ha-1 100m-1, and in Santo Augusto region 64.28% with consumption above the standard. The mean irrigation efficiency for Cruz Alta region was 29.85%, with standard deviation of 5.41%, and for Santo Augusto region, it was 29.02%, with standard deviation of 5.15%.Neste trabalho, são discutidos critérios de eficiência em cada um dos elementos que compõem um pivô central, sendo esta análise aplicada a dois conjuntos de sistemas localizados, nas regiões de Cruz Alta e Santo Augusto, Rio Grande do Sul. A metodologia utilizada associa as avaliações hídrica e energética por meio de um indicador denominado Consumo Específico Normalizado na Irrigação (C ENI, possibilitando, desta forma, uma comparação entre equipamentos e entre projetos. O C ENI na região de Cruz Alta apresentou 72% dos equipamentos acima do padrão (8,68 kWh mm-1 ha-1 100m-1, e na região de Santo Augusto, 64,28% com o consumo acima do padrão. A eficiência de irrigação média para a região de Cruz Alta foi de 29,85%, com desvio-padrão de 5,41%; e para a Região de Santo Augusto foi de 29,02%, com desvio padrão de 5,15%.

  16. 不同颜色类群芒果的ISSR分析%ISSR analysis of different color groups in mango

    Institute of Scientific and Technical Information of China (English)

    张宇; 唐志鹏; 高兴; 杨培丽; 范琪祺; 黄国弟

    2014-01-01

    为给芒果新品种的定向选育提供理论依据,以具有不同果皮颜色的8个芒果品种的叶片为试材,采用ISSR标记技术,筛选出了特异性引物,找到了与芒果果皮颜色性状相关的特异性谱带,并运用NTsys2.10软件进行了聚类分析。结果表明,利用引物UBC-864,可寻找出红色芒果品种群的特有谱带;用引物UBC-840、UBC-857、UBC-864、UBC-868和UBC-890对供试的8份芒果品种资源进行聚类分析,以相似系数0.52为标准,可将供试材料分为2类,台农1号、金煌芒、金穗芒、四季蜜芒、桂热82号聚为一类,凯特芒、爱文芒和红芒6号聚为一类。ISSR标记可用于芒果果皮颜色性状分子标记辅助育种。%In order to provide a theoretical basis for breeding new cultivars of mango, taking eight mango cultivars with different peel colors as materials, some speciifc primers were selected out, some speciifc bands related with fruit color traits were ifnd out by using ISSR marker techniques, and the clustering analysis was conducted with NTsys2.10 software. The results show that some speciifc spectrum bands of the red mango cultivar group can be ifnd out by using primer UBC-864. The eight mango cultivars are cluster into two groups by the primers of UBC-840, UBC-857, UBC-864, UBC-868, UBC-890, taking similarity coefficient 0.52 as a standard. Tainong No.1, Jinhuang, Jinsui, Sijimi, Guire No.82 belong to one group, Keitt, Aiwen and Zill belong to anther group. ISSR markers can be used for molecular marker-assisted breeding for fruit peel color in mango.

  17. The Study of Using Human Patient Simulator for Implementing Critical Nursing Teaching Scheme%应用高级模拟人开展危重症护理教学的方案

    Institute of Scientific and Technical Information of China (English)

    潘玲玲; 赵爱平; 郑微艳; 杨艳; 袁晓玲

    2015-01-01

    Objective To discuss the use of human patient simulator for implementing critical nursing teaching scheme,and to provide reference for high-fidelity simulation teaching and training.Methods By using literature review and theoretical analysis method,the basic framework of the teaching scheme with human patient simulator for critical nursing was determined preliminarily,and expert consultation was used to demonstrate the overall feasibility of the teaching plan.Results The specialist authority coefficient was 0.868.The variation coefficients of feasibilities were all below 0.5.The teaching scheme with human pa-tient simulator for critical nursing simulation training were finally established,which consists of teaching obj ective,contents,arrangement,teachers and evaluation.Among them,the teaching arrangement was con-sisted of six parts ,which include modules,the teaching structure,time arrangement,content,form,teach-ers.Conclusion The teaching scheme with human patient simulator for critical nursing simulation training was rigorous,with strong clinical simulation training feasibility.%目的:探讨采用高级模拟人开展危重症护理教学的方案,以期为高仿真模拟教学和培训提供参考.方法通过文献回顾和理论分析法,初步确立应用高级模拟人开展危重症护理教学方案基本框架,并运用专家现场咨询法论证教学方案的总体可行性.结果专家咨询权威系数Cr=0.868,专家对教学方案的可行性判断变异系数均<0.5,最终确立应用高级模拟人开展危重症护理教学方案,包括教学目标、教学内容、教学安排、师资、教学评价,其中,教学安排部分由模块、具体教学结构、时间安排、内容、形式、教师人数等6个部分构成.结论应用高级模拟人开展危重症护理教学方案严谨,有较强可行性,可应用于临床教学模拟实训.

  18. On Classical Solutions to 2D Shallow Water Equations with Degenerate Viscosities

    Science.gov (United States)

    Li, Yachun; Pan, Ronghua; Zhu, Shengguo

    2017-03-01

    2D shallow water equations have degenerate viscosities proportional to surface height, which vanishes in many physical considerations, say, when the initial total mass, or energy are finite. Such a degeneracy is a highly challenging obstacle for development of well-posedness theory, even local-in-time theory remains open for a long time. In this paper, we will address this open problem with some new perspectives, independent of the celebrated BD-entropy (Bresch et al in Commun Math Phys 238:211-223, 2003, Commun Part Differ Eqs 28:843-868, 2003, Analysis and Simulation of Fluid Dynamics, 2007). After exploring some interesting structures of most models of 2D shallow water equations, we introduced a proper notion of solution class, called regular solutions, and identified a class of initial data with finite total mass and energy, and established the local-in-time well-posedness of this class of smooth solutions. The theory is applicable to most relatively physical shallow water models, broader than those with BD-entropy structures. We remark that our theory is on the local strong solutions, while the BD entropy is an essential tool for the global weak solutions. Later, a Beale-Kato-Majda type blow-up criterion is also established. This paper is mainly based on our early preprint (Li et al. in 2D compressible Navier-Stokes equations with degenerate viscosities and far field vacuum, preprint. arXiv:1407.8471, 2014).

  19. Occupational zoonoses in zoo and wildlife veterinarians in India: A review

    Directory of Open Access Journals (Sweden)

    H. B. Chethan Kumar

    2013-06-01

    Full Text Available Zoos and biological parks are considered as a hub for public ecreation and education. This is highlighted by the fact that visitors to the zoos are increasing year by year and they generate sizeable revenue. Veterinary professionals play a pivotal role in health management of wild animals in zoos and biological parks. Since veterinarians work in close contact with wild animals, there is a potential risk of transmission of zoonotic diseases from wild animals to humans and vice versa. There are approximately 1415 infectious agents causing diseases in humans, out of which 868 (61% are known to be zoonotic in nature. It is also important to note that more than 70% of the emerging zoonotic diseases have wild animals as reservoir hosts. The major zoonotic diseases that are transmitted from wild animals to humans include rabies, anthrax, leptospirosis, Q-fever, psittacosis, hendra virus, nipah virus, herpes B encephalitis, toxoplasmosis, etc. Hence, it is imperative for veterinarians and zoo staff to be fully aware of the knowledge pertaining to the source, transmission, pathogenicity, treatment and control of zoonotic diseases. In this manuscript, we provide key information regarding zoonotic diseases and also recommend important measures for their control and prevention. The information provided here will be highly beneficial for personnel who work in close association with wild animals

  20. A Unified Model of Program Behavior

    Science.gov (United States)

    1992-12-01

    0.14324 0.00049 0.91487 pmac .001 0.05683 0.98721 0.01230 0.00048 0.94317 spic.000 (dup) 0.08368 0.90566 0.09272 0.00162 0.91632 spic.001 0.06773...000 (dup) 0.628 0.868 0.017 0.032 0.040 0.023 0.020 lisp.001 0.627 0.871 0.014 0.029 0.035 0.028 0.023 pmac .001 0.622 0.857 0.015 0.044 0.046 0.019...lisp.001 0.909 0.170 0.822 0.007 0.091 pmac .001 0.960 0.087 0.903 0.010 0.040 spic.000 (dup) 0.823 0.181 0.813 0.007 0.177 spic.001 0.871 0.224 0.772

  1. Development of porous Ti6Al4V/chitosan sponge composite scaffold for orthopedic applications

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Miao [College of Life Information Science & Instrument Engineering, Hangzhou Dianzi University, Hangzhou 310018 (China); Li, Xiang, E-mail: Xiangliwj@sjtu.edu.cn [School of Mechanical Engineering, Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration, Shanghai 200240 (China)

    2016-01-01

    A novel composite scaffold consisting of porous Ti6Al4V part filled with chitosan sponge was fabricated using a combination of electron beam melting and freeze-drying. The mechanical properties of porous Ti6Al4V part were examined via compressive test. The ultimate compressive strength was 85.35 ± 8.68 MPa and the compressive modulus was 2.26 ± 0.42 GPa. The microstructure of composite scaffold was characterized using scanning electron microscopy. The chitosan sponge filled in Ti6Al4V part exhibited highly porous and well-interconnected micro-pore architecture. The osteoblastic cells were seeded on scaffolds to test their seeding efficiency and biocompatibility. Significantly higher cell seeding efficiency was found on composite scaffold. The biological response of osteoblasts on composite scaffolds was superior in terms of improved cell attachment, higher proliferation, and well-spread morphology in relation to porous Ti6Al4V part. These results suggest that the Ti6Al4V/chitosan composite scaffold is potentially useful as a biomedical scaffold for orthopedic applications. - Highlights: • A novel composite scaffold with sufficient mechanical properties and favorable cell affinity environment was developed. • Significantly higher cell seeding efficiency was found on composite scaffold. • The osteoblasts on composite scaffolds showed well-spread morphology, improved cell attachment and higher proliferation.

  2. The Light Hadron Spectrum and Decay Constants in Quenched Lattice QCD

    CERN Document Server

    Allton, C R; Sachrajda, Christopher T C; Wittig, H; Baxter, R M; Booth, S P; Bowler, K C; Henty, D S; Kenway, R D; McNeile, C; Pendleton, B J; Richards, D G; Simone, J N; Simpson, A D

    1994-01-01

    We present results for light hadrons composed of both degenerate and non-degenerate quarks in quenched lattice QCD. We calculate masses and decay constants using 60 gauge configurations with an $O(a)$--improved fermion action at $\\beta = 6.2$. Using the $\\rho$ mass to set the scale, we find hadron masses within two to three standard deviations of the experimental values (given in parentheses): $m_{K^*}=868\\er{9}{8}$~MeV (892~MeV), $m_{\\phi}=970\\err{20}{10}$~MeV (1020~MeV), $m_N=820\\err{90}{60}$~MeV (938~MeV), $m_\\Delta=1300\\errr{100}{100}$~MeV (1232~MeV) and $m_\\Omega=1650\\err{70}{50}$~MeV (1672~MeV). Direct comparison with experiment for decay constants is obscured by uncertainty in current renormalisations. However, for ratios of decay constants we obtain $f_K/f_\\pi=1.20\\er{3}{2}$ (1.22) and $f_\\phi/f_\\rho=1.13\\er{2}{3}$ (1.22).

  3. Comparison of Sputum Smear Microscopy and Rapid Tuberculosisantibody Detection Test Kits for Diagnosis of Pulmonary Tuberculosis in Abia State, Nigeria

    Institute of Scientific and Technical Information of China (English)

    Emmanuel Olufemi Ekundayo[1; Sam D. Abbey[2; Onuka Okorie[3

    2014-01-01

    The SSM (sputum smear microscopy) and five immunochromatographic tuberculosis antibody detection tests (DiaSpot TB, Spodex TB, SD Rapid TB, Clinotech TB Screen and Precious One-step TB) were compared for diagnosis of active TB at the Leprosy and Tuberculosis Referral Hospital, Uzuakoli, Abia State, Nigeria. Sputum specimens from 150 study participants (male/female ratio, 0.81) were cultured on Lowenstein-Jensen slopes and direct smears were stained by Ziehl-Neelsen technique and examined by light microscopy. Sera were tested for anti-TB antibodies using the rapid TB tests. A total of 91 participants were culture positive, 79 (86.8%) for M. tuberculosis and 12 (13.2%) for nontuberculous mycobacteria. The sensitivity of SSM was 50% (95% CI: 39.0-61.0) and specificity was 92.3% (95% CI: 86.4-98.2) in those culture positive for M. tuberculosis. The sensitivity and specificity of the Rapid TB tests ranged from 24.1-39.2% and 78.4-87.8%, respectively. None of the five rapid TB tests had acceptable level of accuracy for diagnosis of active TB. The sensitivity of SSM though moderate is inadequate for long term TB control in this setting.

  4. KNOWLEDGE OF EMERGENCY CONTRACEPTIVES AMONG WOMEN OF REPRODUCTIVE AGE GROUP

    Directory of Open Access Journals (Sweden)

    Singh

    2016-04-01

    Full Text Available BACKGROUND As per data from WHO, 21.6 million unsafe abortions occurred globally in 2008, out of which 47,000 women died from abortionrelated complications, contributing to 13% of global maternal mortality. (1 Emergency contraceptive can be used after intercourse to prevent pregnancy in case of unprotected intercourse, contraceptive failure or sexual assault. A considerable proportion of these abortions can be prevented by the timely use of emergency contraception. OBJECTIVES To study the knowledge of emergency contraceptives among women of reproductive age group. METHODS This is a government hospital-based prospective study done for a period of 3 months. The study included 500 women of reproductive age group (16 years to 40 years attending OPD of Obstetrics and Gynaecology Department of IGMC and RI, Pondicherry. A predesigned questionnaire is provided to women asking about awareness regarding emergency contraceptives. RESULTS Majority of them were between 20 and 30 years of age, 59.6% were from urban background and 86.8% were educated; 66% of them had used regular method of contraception some time in their life, but the awareness level of emergency contraceptives was found to be only 5.4% of which only 2% (n=10 had ever used emergency contraceptives. CONCLUSION Emergency contraceptives is an effective means of preventing unwanted pregnancies, but unfortunately majority of women lack awareness about the emergency methods. Efforts should be focused on providing health education regarding EC among females through media and health professionals.

  5. Avaliação de sauveiros externos em eucaliptais de Minas Gerais

    Directory of Open Access Journals (Sweden)

    Iris Cristiane Magistrali

    2011-06-01

    Full Text Available Existe uma grande dificuldade em aperfeiçoar as técnicas de manejo de formigas cortadeiras, sobretudo no que diz respeito aos sauveiros externos localizados próximos a plantios florestais. Por causa disso, o presente trabalho teve por objetivo caracterizar aspectos como tamanho e distância de sauveiros externos em plantações de eucaliptos. A avaliação foi realizada em aceiros externos de três fazendas localizadas nos municípios de João Pinheiro e Buritizeiro, em Minas Gerais, seis meses após ser realizado o combate convencional às formigas cortadeiras. Foram encontrados nove sauveiros externos, com área média de terra solta de 62,5 ± 11,1 m2, localizados a uma distância média de 33,94 ± 8,68 metros entre a margem do plantio e o local do formigueiro. Constatou-se que tais características podem ser úteis no ajuste da largura da faixa de segurança de combate, a qual deve ser igual a 50 m. O gênero Trachymyrmex e as espécies Atta laevigata e Atta sexdens rubropilosa foram registrados como ocorrências novas no município de Buritizeiro, e o gênero Acromyrmex como uma nova ocorrência nos dois municípios.

  6. The effects of evolution education: examining attitudes toward and knowledge of evolution in college courses.

    Science.gov (United States)

    Short, Stephen D; Hawley, Patricia H

    2015-01-20

    The present study examined changes in university students' attitudes toward and knowledge of evolution measured by the previously validated Evolutionary Attitudes and Literacy Survey (EALS) in response to curricular content. Specifically, student responses on the survey were compared across an evolutionary psychology course, an introductory biology course with significant evolutionary content, and a political science course with no evolutionary content. To this end, 868 students were assessed at a large Midwestern U.S. university prior to and following completion of one of the three courses. A multiple group repeated measures confirmatory factor analysis (CFA) was conducted to examine latent mean differences in self-reported Evolution Knowledge/Relevance, Creationist Reasoning, Evolutionary Misconceptions, and Exposure to Evolution. A significant and notable increase in Knowledge/Relevance, as well as decreases in Creationist Reasoning and Evolutionary Misconceptions, was observed for the evolutionary psychology course, whereas the biology course demonstrated no change in Knowledge/Relevance and a significant increase in Evolutionary Misconceptions. The implications of these findings for evolution education are discussed.

  7. [Feeding habits of immature individuals of Ephemeroptera, Plecoptera, and Trichoptera from middle reaches of a tropical mountain stream].

    Science.gov (United States)

    Guzmán-Soto, Cristian José; Tamarís-Turizo, Cesar Enrique

    2014-04-01

    Morphological and behavioral aspects of insects allow their grouping in trophic guilds and represent their dependence on food resources. We determined the feeding habits of immature organisms of Ephemeroptera, Plecoptera, and Trichoptera (EPT) from the middle reaches of Gaira stream (Sierra Nevada de Santa Marta, Colombia), using gut content analysis. We identified 13 EPT genera, but only ten were analyzed for a total of 100 organisms. We describe six food items: animal parts (AP), vascular plant tissue (VPT), microalgae (M), fungi (F), coarse particulate organic matter (CPOM) and fine particulate organic matter (FPOM). Baetodes was determined to be a collector-scraper, since FPOM represented 46.6% of food content, followed by F (38.4%). Chimarra, Leptohyphes, Lachlania, and Thraulodes were categorized as collectors with average proportions of FPOM 86.8%, 93.1%, 93.1% and 93.7%, respectively. Phylloicus, Smicridea and Leptonema were main consumers of VPT and CPOM with proportions of 76.3%, 54.6%, and 62.4%, respectively; while ratios of FPOM were 22.3%, 38.8%, and 32.9%, respectively. While all are detritivores, Phylloicus is functionally classified as shredders and Smicridea and Leptonema as collectors. Atopsyche and Anacroneuria were the only taxa in which AP were observed in high proportions, 57.9% and 58.2%, respectively, for that reason they were classified as predators. The organisms examined consume a wide variability of resources.

  8. Allogeneic transplantation for therapy-related myelodysplastic syndrome and acute myeloid leukemia.

    Science.gov (United States)

    Litzow, Mark R; Tarima, Sergey; Pérez, Waleska S; Bolwell, Brian J; Cairo, Mitchell S; Camitta, Bruce M; Cutler, Corey S; de Lima, Marcos; Dipersio, John F; Gale, Robert Peter; Keating, Armand; Lazarus, Hillard M; Luger, Selina; Marks, David I; Maziarz, Richard T; McCarthy, Philip L; Pasquini, Marcelo C; Phillips, Gordon L; Rizzo, J Douglas; Sierra, Jorge; Tallman, Martin S; Weisdorf, Daniel J

    2010-03-04

    Therapy-related myelodysplastic syndromes (t-MDSs) and acute myeloid leukemia (t-AML) have a poor prognosis with conventional therapy. Encouraging results are reported after allogeneic transplantation. We analyzed outcomes in 868 persons with t-AML (n = 545) or t-MDS (n = 323) receiving allogeneic transplants from 1990 to 2004. A myeloablative regimen was used for conditioning in 77%. Treatment-related mortality (TRM) and relapse were 41% (95% confidence interval [CI], 38-44) and 27% (24-30) at 1 year and 48% (44-51) and 31% (28-34) at 5 years, respectively. Disease-free (DFS) and overall survival (OS) were 32% (95% CI, 29-36) and 37% (34-41) at 1 year and 21% (18-24) and 22% (19-26) at 5 years, respectively. In multivariate analysis, 4 risk factors had adverse impacts on DFS and OS: (1) age older than 35 years; (2) poor-risk cytogenetics; (3) t-AML not in remission or advanced t-MDS; and (4) donor other than an HLA-identical sibling or a partially or well-matched unrelated donor. Five-year survival for subjects with none, 1, 2, 3, or 4 of these risk factors was 50% (95% CI, 38-61), 26% (20-31), 21% (16-26), 10% (5-15), and 4% (0-16), respectively (P < .001). These data permit a more precise prediction of outcome and identify subjects most likely to benefit from allogeneic transplantation.

  9. Comparison of Retrograde Balloon Dilatation and Laparoscopic Pyeloplasty for Treatment of Ureteropelvic Junction Obstruction: Results of a 2-Year Follow-Up.

    Directory of Open Access Journals (Sweden)

    Ning Xu

    Full Text Available To evaluate the efficacy of laparoscopic pyeloplasty relative to retrograde balloon dilatation for the treatment of ureteropelvic junction obstruction (UPJO.This retrospective study enrolled UPJO patients with stricture length < 2 cm who had been treated with laparoscopic pyeloplasty (LP; 44 cases or balloon dilatation (BD; 38 cases from Jan 2010 to Jan 2012, according to patients' preference after consultation. Demographics and clinical parameters were collected. Patients were followed-up at 3, 6, 12, and 24 months. Ultrasonography, intravenous urography, and diuretic renography were applied to evaluate the remission of hydronephrosis.Both groups were comparable with respect to age, UPJO location, gender, and other baseline parameters. Compared to the LP group, patients receiving BD experienced significantly shorter operative time, analgesia time, hospital stay, and urethral catheter indwelling time, and less cost (P<0.001. Three and 6 months after their respective procedures, the success rates of the LP (97.7%, both and BD (94.7% and 86.8% groups were similar, and at 12 and 24 months the long-term success rate of LP (95.5%, both was better than that of BD (78.9% and 71.0%.LP showed better long-term success rate than did BD in the management of UPJO with length of stricture < 2 cm. Considering that BD is more minimally invasive, simpler and easier to perform, and costs less, we recommend it for some selective UPJO patients as the first-line therapy.

  10. Radiometric calibration stability of the EO-1 advanced land imager: 5 years on-orbit

    Science.gov (United States)

    Markham, B.L.; Ong, L.; Barsi, J.A.; Mendenhall, J.A.; Lencioni, D.E.; Helder, D.L.; Hollaren, D.M.; Morfitt, R.

    2006-01-01

    The Advanced Land Imager (ALI) was developed as a prototype sensor for follow on missions to Landsat-7. It was launched in November 2000 on the Earth Observing One (EO-1) satellite as a nominal one-year technology demonstration mission. As of this writing, the sensor has continued to operate in excess of 5 years. Six of the ALl's nine multi-spectral (MS) bands and the panchromatic band have similar spectral coverage as those on the Landsat-7 ETM+. In addition to on-board lamps, which have been significantly more stable than the lamps on ETM+, the ALI has a solar diffuser and has imaged the moon monthly since launch. This combined calibration dataset allows understanding of the radiometric stability of the ALI system, its calibrators and some differentiation of the sources of the changes with time. The solar dataset is limited as the mechanism controlling the aperture to the solar diffuser failed approximately 18 months after launch. Results over 5 years indicate that: the shortest wavelength band (443 nm) has degraded in response about 2%; the 482 nm and 565 nm bands decreased in response about 1%; the 660 nm, 790 nm and 868 nm bands each degraded about 5%; the 1250 nm and 1650 nm bands did not change significantly and the 2215 nm band increased in response about 2%.

  11. Collection of peripheral progenitor cells: a comparison between Amicus and Cobe-Spectra blood cell separators.

    Science.gov (United States)

    Adorno, Gaspare; Del Proposto, Gianpaolo; Palombi, Francesca; Bruno, Antonio; Ballatore, Giovanna; Postorino, Massimiliano; Tendas, Andrea; Del Poeta, Giovanni; Isacchi, Giancarlo; Amadori, Sergio

    2004-04-01

    The authors compared the efficiency of two different blood cell separators (Amicus and Cobe-Spectra) in collecting peripheral blood progenitor cells for autologous or homologous transplantation. A total number of 129 procedures were performed, 36 with Spectra, 93 with Amicus. There was no difference between Spectra and Amicus efficiencies for CD34+ cell collection (46.685% vs 46.235%; p=n.s) but the platelet efficiencies were 17.31% and 12.54% respectively (p=0.04) and, if autologous and allogeneic collections were considered separately, a marked difference resulted in allogeneic platelet efficiency between 6 Spectra and 23 Amicus procedures (26.83% vs 8.68%, p=0.0004). The authors were able to demonstrate that in 70 Amicus autologous collections there was a different platelet efficiency, if peripheral count was considered: 12 procedures performed with a platelet count > 100 x 10(9)/l had a very low efficiency (6.86%), but this value increased if platelet count lowered (13.02% if between 100 and 50 x 10(9)/l, 22.63% if between 50 and 0 x 10(9)/l, 23 and 35 procedures respectively). The study is preliminary and the number of collections is little, but the overall data suggest that Spectra (AutoPBSC, V 6.0) and Amicus separators have the same efficiency for collecting CD34+ cells while Amicus procedures have a very low platelet contamination, especially with donors.

  12. Determination on Iron, Copper, Chromium, Cadmium, Lead, Nickel and Cobalt in Hair Dye%染发剂中铁、铜、铬、镉、铅、镍和钴等重金属含量测定

    Institute of Scientific and Technical Information of China (English)

    解楠; 顾宇翔; 周泽琳

    2012-01-01

    建立了微波消解前处理,电感耦合等离子发射光谱(ICP-AES)测定染发剂中铁、铜、铬、镉、铅、镍和钴等重金属含量的方法.该方法各元素检出限均为0.05 mg/kg,线性范围0~500 ng/mL,加标回收率86.8%~108.0%,相对标准偏差为0.98%~5.54%.该方法简便、灵敏,结果稳定准确,可以用于染发剂中重金属含量的测定.%An inductively coupled plasma-atomic emission spectrometry (ICP-AES) with samples microwave digestion method for determination of Iron, Copper, Chromium, Cadmium, Lead, Nickel and Cobalt in hair dye was established. The detection limits of all elements were 0.05 mg/kg, the linearity ranged from 0 to 500 ng/mL, and recoveries of samples were in the range of 86. 8%~108. 0%, the RSD of precision is from 0. 98% to 5.54%. It indicates that the method is simple, sensitive, stable and accurate, which can be used for the determination of heavy metal elements in hair dye.

  13. The fusion rules for the Temperley-Lieb algebra and its dilute generalization

    Science.gov (United States)

    Belletête, Jonathan

    2015-10-01

    The Temperley-Lieb (TL) family of algebras is well known for its role in building integrable lattice models. Even though a proof is still missing, it is agreed that these models should go to conformal field theories in the thermodynamic limit and that the limiting vector space should carry a representation of the Virasoro algebra. The fusion rules are a notable feature of the Virasoro algebra. One would hope that there is an analogous construction for the TL family. Such a construction was proposed by Read and Saleur (2007 Nucl. Phys. B 777 316) and partially computed by Gainutdinov and Vasseur (2013 Nucl. Phys. B 868 223-70) using the bimodule structure over the TL algebras and the quantum group Uq (sl2).We use their definition for the dilute Temperley-Lieb (dTL) family, a generalization of the original TL family. We develop a new way of computing fusion by using induction and show its power by obtaining fusion rules for both dTL and TL. We recover those computed by Gainutdivov and Vasseur and new ones that were beyond their scope. In particular, we identify a set of irreducible TL- or dTL-representations whose behavior under fusion is that of some irreducibles of the minimal models of conformal field theory.

  14. Attitudes and beliefs on the establishment of a national food safety authority in Cyprus. A population-based survey.

    Science.gov (United States)

    Hadjigeorgiou, Andreas; Talias, Michael A; Soteriades, Elpidoforos S; Philalithis, Anastasios; Psaroulaki, Anna; Gikas, Achilleas; Tselentis, Yiannis

    2014-04-01

    Cyprus does not have a National Food Safety Authority (NFSA), but a multi-level, fragmented system with responsibilities divided among different ministries and governmental agencies, frequently impeding efforts to effectively manage food risks by duplication and overlapping of responsibilities. A population-based survey was carried out to determine the beliefs and attitudes of interested parties concerning the establishment of a NFSA in Cyprus. Information was collected using a random stratified sampling design and a structured questionnaire. A total of 868 questionnaires were collected (704 from regular consumers, 154 from food businesses' representatives, and 10 from public services' directors or acting head officers). About 11% of food businesses' representatives and 45% of consumers reported that they did not know which public authorities are responsible for food control. Moreover, 2 out of 10 (17%) of responders from public agencies, 70% from food businesses and 91% from consumers, although not aware of ongoing efforts to establish a food safety authority in Cyprus (currently under consideration), were supportive of the idea [8 out of 10 (83%) of responders from public services, 93% from food businesses, and 89% of consumers]. Finally, 7 out of 10 (67%) from the public agencies and 84% of representatives from food businesses agreed with the separation of risk assessment from risk management activities. Public opinion in Cyprus as well as public agencies and food businesses' representatives support the establishment of a single independent national food safety authority in Cyprus based on the European paradigm including the division of risk activities.

  15. Characterization of Lentinus edodes β-glucan influencing the in vitro starch digestibility of wheat starch gel.

    Science.gov (United States)

    Zhuang, Haining; Chen, Zhongqiu; Feng, Tao; Yang, Yan; Zhang, Jingsong; Liu, Guodong; Li, Zhaofeng; Ye, Ran

    2017-06-01

    Lentinus edodes β-glucan (abbreviated LEBG) was prepared from fruiting bodies of Lentinus edodes. The average molecular weight (Mw) and polydispersity index (Mw/Mn) of LEBG were measured to be 1.868×10(6)g/mol and 1.007, respectively. In addition, the monosaccharide composition of LEBG was composed of arabinose, galactose, glucose, xylose, mannose with a molar ratio of 5:11:18:644:16. After adding LEBG, both G' and G″ of starch gel increased. This is mainly because the connecting points between the molecular chains of LEBG and starch formed so that gel network structures were enhanced. The peak temperature in the heat flow diagram shifted to a higher temperature and the peak area of the endothermic enthalpy increased. Furthermore, LEBG can significantly inhibit starch hydrolysis. The predicted glycemic index (pGI) values were reduced when starch was replaced with LEBG at 20% (w/w). It might indicate that LEBG was suitable to develop low GI noodle or bread.

  16. Knowledge and attitudes of physicians and pharmacists towards the use of generic medicines in Bosnia and Herzegovina.

    Science.gov (United States)

    Čatić, Tarik; Avdagić, Lejla; Martinović, Igor

    2017-02-01

    Aim To investigate and assess knowledge and attitudes of pharmacists and physicians towards generic drugs prescription in order to evaluate current trends, obstacles to prescribe/dispense generics and suggest possible improvements of rational and economic prescribing having in mind scarce public budgets for drugs. Methods A cross-sectional survey among 450 primary care physicians (prescribers) and pharmacists in four major cities in Bosnia and Herzegovina (Sarajevo, Banja Luka, Tuzla and Mostar) during the period between January and March 2016 was conducted. The survey (questionnaire) was developed and physicians' and pharmacists' perception was examined using the 5-point Likert scale. Descriptive statistics was used to examine respondents' characteristics and their responses to survey questions. The respondents perception based on different characteristics was assessed using ordinal logistic regression. Results Generally, positive attitudes towards generic drugs were found. Majority of respondents, 392 (87.0%) considered generic drugs the same as originators and they could be mutually substituted. Physicians were more likely to prescribe branded drugs, 297 (66.6%), even 391 (86.8%) were aware of generic alternatives. Respondents believed that patients considered generic drugs less effective, 204 (45.4%), and 221 (49.0%) disapproved generic substitution. Conclusion Our findings suggest that further education and more information about benefits of generic drugs should be provided to key stakeholders including patients. Also, clearer generic drugs policies should be introduced in order to improve generic prescribing and potentially improve access and optimize pharmaceutical public expenditures.

  17. Dietary, Lifestyle and Socio-Economic Correlates of Overweight, Obesity and Central Adiposity in Lebanese Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Lara Nasreddine

    2014-03-01

    Full Text Available The Eastern Mediterranean region is characterized by one of the highest burdens of paediatric obesity worldwide. This study aims at examining dietary, lifestyle, and socio-economic correlates of overweight, obesity, and abdominal adiposity amongst children and adolescents in Lebanon, a country of the Eastern Mediterranean basin. A nationally representative cross-sectional survey was conducted on 6–19-year-old subjects (n = 868. Socio-demographic, lifestyle, dietary, and anthropometric data (weight, height, waist circumference were collected. Overweight and obesity were defined based on BMI z-scores. Elevated waist circumference (WC and elevated waist to height ratio (WHtR were used as indices of abdominal obesity. Of the study sample, 34.8% were overweight, 13.2% were obese, 14.0% had elevated WC, and 21.3% had elevated WHtR. Multivariate logistic regression analyses showed that male gender, maternal employment, residence in the capital Beirut, sedentarity, and higher consumption of fast food and sugar sweetened beverages were associated with increased risk of obesity, overweight, and abdominal adiposity, while regular breakfast consumption, higher intakes of milk/dairies and added fats/oils were amongst the factors associated with decreased risk. The study’s findings call for culture-specific intervention strategies for the promotion of physical activity, healthy lifestyle, and dietary practices amongst Lebanese children and adolescents.

  18. Production of 15N-enriched nitric acid (H15NO3

    Directory of Open Access Journals (Sweden)

    C. R. Sant Ana Filho

    2008-12-01

    Full Text Available Techniques that employ 15N have proved to be an important tool in many areas of the agronomic and biomedical sciences. Nevertheless, their use is limited by methodological difficulties and by the price of compounds in the international market. Nitric compounds (15NO3- have attracted the interest of researchers. However, these compounds are not currently produced in Brazil. Thus, in the present work H15NO3 was obtained from the oxidation of anhydrous 15NH3. The method we used differs from the industrial process in that the absorption tower is replaced with a polytetrafluoroethylene-lined, stainless-steel hydration reactor. The process output was evaluated based on the following parameters: reaction temperature; ratio of reagents; pressure and flow of 15NH3(g through the catalyst (Pt/Rh. The results showed that, at the best conditions (500 ºC; 50 % excess O2; 0.4 MPa; and 3.39 g.min-1 of 15NH3, a conversion percentage (N-15NH3 to N-15NO3- of 62.2 %, an overall nitrogen balance (N-15NH3 + N-15NO3- of 86.8 %, and purity higher than 99 % could be obtained.

  19. Confounded winter and spring phenoclimatology on large herbivore ranges

    Science.gov (United States)

    Christianson, David; Klaver, Robert W.; Middleton, Arthur; Kauffman, Matthew

    2013-01-01

    Annual variation in winter severity and growing season vegetation dynamics appear to influence the demography of temperate herbivores but parsing winter from spring effects requires independent metrics of environmental conditions specific to each season. We tested for independence in annual variation amongst four common metrics used to describe winter severity and early growing season vegetation dynamics across the entire spatial distribution of elk (Cervus elaphus) in Wyoming from 1989 to 2006. Winter conditions and early growing season dynamics were correlated in a specific way. Winters with snow cover that ended early tended to be followed by early, but slow, rises in the normalized difference vegetation index (NDVI), while long winters with extended periods of snow cover were often followed by late and rapid rises in NDVI. Across the 35 elk ranges, 0.4–86.8 % of the variation in the rate of increase in NDVI’s in spring was explained by the date snow cover disappeared from SNOTEL stations. Because phenoclimatological metrics are correlated across seasons and shifting due to climate change, identifying environmental constraints on herbivore fitness, particularly migratory species, is more difficult than previously recognized.

  20. Synthesis and evaluation of antioxidant properties of novel 1,2,4-triazole-based schiff base heterocycles.

    Science.gov (United States)

    Aswathanarayanappa, Chandrashekar; Bheemappa, Eswarappa; Bodke, Yadav D; Krishnegowda, Peethambar S; Venkata, Srinivas P; Ningegowda, Raghu

    2013-12-01

    A series of 1,2,4-triazole-based Schiff base heterocyclic compounds (5a-f and 8a-i) and phenethylamines (7a-h) were synthesized and evaluated for antioxidant properties by free-radical scavenging, anti-hemolytic activity, lipid peroxidation, and their protective effects against DNA oxidative damage. Compounds 7c, 7d, 7h, 8b, and 8i showed promising DPPH(•) radical scavenging activity with the level of inhibition between 86.8% and 94%. Compounds 8a, 8b, 8d, 8g, and 8i were effective against the oxidative hemolysis of human erythrocytes and lipid peroxidation, in a dose-dependent manner, with IC50 values in the range of 55.7-80.7 and 53.2-81.2 µg/mL, respectively. Compounds 8a and 8b were effective against oxidative damage on erythrocyte ghost membrane proteins, and 8g and 8i were able to protect against DNA oxidative damage.

  1. Synergism effect of 131 I-Herceptin and high-energy X-ray on HER2 overexpressed breast cancer cells%131 I-Herceptin联合高能X线对HER2高表达人乳腺癌细胞的协同杀伤及机制研究

    Institute of Scientific and Technical Information of China (English)

    张迎; 袁胜利; 郑勤; 张全安; 徐瀚峰

    2015-01-01

    目的:研究131 I-Herceptin联合高能X线对HER2高表达人乳腺癌SK-BR-3细胞的协同杀伤及机制。方法运用免疫组化法、荧光原位杂交法(fluorescence in situ hybridization,FISH)检测SK-BR-3细胞的人类表皮生长因子受体2(human epidermal growth factor receptor-2,HER2)蛋白表达和基因扩增,采用Iodogen法制备131 I-Herceptin,MTT法筛选131 I-Herceptin杀伤SK-BR-3细胞的IC15浓度。根据是否应用131I-Herceptin分为对照组及加药组,分别给予高能X线(0、2、4、6 Gy),以克隆形成试验分析协同杀伤效应;将细胞分为空白对照组、药物组(131I-Herceptin)、高能X线组(2Gy)、联合组(131I-Herceptin+2Gy),以A0/EB法检测细胞凋亡率及死亡率,以流式细胞仪检测各组细胞周期。结果 SK-BR-3细胞为HER2高表达细胞。131 I-Herceptin的标记率为86.8%,放射化学纯度为93.9%,放射性比活度为868.3μci/mg。131I-Herceptin的IC15为15.625μci/mL。发现131I-Herceptin(F=628.008,P<0.05)及高能X线(F=964.970,P<0.05)对SK-BR-3细胞均有显著的杀伤作用,可明显降低细胞的SF值,且2者具有交互作用(F=113.046,P<0.05),即2者协同降低SF值。空白组、外照射组、药物组及联合组细胞凋亡率与死亡率比较差异均有统计学意义(F=103.324,F=13.330,均P<0.05),且两两比较差异均有统计学意义(P<0.05);经外照射及131I-Herceptin联合作用后,细胞周期均发生明显改变,由G1期向G2期和S期转移。结论131 I-Herceptin 联合高能X线对HER2高表达人乳腺癌SK-BR-3细胞具有协同杀伤作用。%Objective To study the synergism effect of 131 I-Herceptin and high-energy X-ray on HER2 overexpressed breast cancer SK-BR-3 cells.Methods The protein expression and gene amplification of human epidermal growth factor receptor-2 ( HER2 ) in SK-BR-3 cells were identified by

  2. Influence of Structural Features and Physico-chemical Properties of Metal-carbon Nanocomposites with Ferromagnetic Metal Inclusions on Microwave Radiation

    Directory of Open Access Journals (Sweden)

    L. Kozhitov

    2014-07-01

    Full Text Available Metal-carbon nanocomposites on the basis of polyacrylonitrile and compounds of metals (Fe, Ni, Co synthesized at IR-heating and studied by SEM, X-ray phase analysis, Raman scattering, IR Fourier spectroscopy are characterized by the carbon nanostructured amorphous graphite matrix with uniformly distributed nanoparticles of metals (10-30 nm, their oxides and compounds – FeNi3 and FeCo, multilayered carbon nanotubes (~ 7-22 nm, and in the composition of Fe-Co / C fullerene-like formations – C60. All nanocomposites feature high absorption of electromagnetic waves in the frequency range 20-40 GHz. Two absorption mechanisms are proposed: dielectric loss in the amorphous carbon matrix and scattering of electric and magnetic components by ferromagnetic inclusions. Absorption was – 8.68 dB for Fe-Ni / C, – 12.93 dB for Fe / C, and – 7.07 dB for Ni / C and for Fe-Co / C was found to be maximum in the whole range studied (more than – 40 dB with a peak of – 52.83 dB at 24.27 GHz, which is explained probably by both high nanocomposite electric conductivity 2 S / m and high specific magnetization of phase FeCo.

  3. A Comparison of Gluteus Maximus, Biceps Femoris, and Vastus Lateralis Electromyographic Activity in the Back Squat and Barbell Hip Thrust Exercises.

    Science.gov (United States)

    Contreras, Bret; Vigotsky, Andrew D; Schoenfeld, Brad J; Beardsley, Chris; Cronin, John

    2015-12-01

    The back squat and barbell hip thrust are both popular exercises used to target the lower body musculature; however, these exercises have yet to be compared. Therefore, the purpose of this study was to compare the surface electromyographic (EMG) activity of the upper and lower gluteus maximus, biceps femoris, and vastus lateralis between the back squat and barbell hip thrust. Thirteen trained women (n = 13; age = 28.9 years; height = 164 cm; mass = 58.2 kg) performed estimated 10-repetition maximums (RM) in the back squat and barbell hip thrust. The barbell hip thrust elicited significantly greater mean (69.5% vs 29.4%) and peak (172% vs 84.9%) upper gluteus maximus, mean (86.8% vs 45.4%) and peak (216% vs 130%) lower gluteus maximus, and mean (40.8% vs 14.9%) and peak (86.9% vs 37.5%) biceps femoris EMG activity than the back squat. There were no significant differences in mean (99.5% vs 110%) or peak (216% vs 244%) vastus lateralis EMG activity. The barbell hip thrust activates the gluteus maximus and biceps femoris to a greater degree than the back squat when using estimated 10RM loads. Longitudinal training studies are needed to determine if this enhanced activation correlates with increased strength, hypertrophy, and performance.

  4. Relation of tricuspid annular displacement and tissue Doppler imaging velocities with duration of weaning in mechanically ventilated patients with acute pulmonary edema

    Directory of Open Access Journals (Sweden)

    Dragoumanis Christos K

    2010-05-01

    Full Text Available Abstract Background Liberation from the ventilator is a difficult task, whereas early echocardiographic indices of weaning readiness are still lacking. The aim of this study was to test whether tricuspid annular plane systolic excursion (TAPSE and right ventricular (RV systolic (Sm and diastolic (Em & Am tissue Doppler imaging (TDI velocities are related with duration of weaning in mechanically ventilated patients with acute respiratory failure due to acute pulmonary edema (APE. Methods Detailed quantification of left and right ventricular systolic and diastolic function was performed at admission to the Intensive Care Unit by Doppler echocardiography, in a cohort of 32 mechanically ventilated patients with APE. TAPSE and RV TDI velocities were compared between patients with and without prolonged weaning (≥ or Results Patients with prolonged weaning (n = 12 had decreased TAPSE (14.59 ± 1.56 vs 19.13 ± 2.59 mm, Sm (8.68 ± 0.94 vs 11.62 ± 1.77 cm/sec and Em/Am ratio (0.98 ± 0.80 vs 2.62 ± 0.67, p 2 = 0.53, beta slope = 0.76, p 2 = 0.52, beta = 0.75, p 2 = 0.57, beta = 0.32, p Conclusions We suggest that in mechanically ventilated patients with APE, low TAPSE and RV TDI velocities upon admission are associated with delayed liberation from mechanical ventilation, probably due to more severe LV heart failure.

  5. Analysis of 13 asteroid lightcurves obtained at the Palmer Divide Observatory

    Science.gov (United States)

    Warner, Brian D.

    2006-06-01

    The lightcurves for the following asteroids were obtained and then analyzed to find the synodic period and amplitude. 321 Florentina: 2.8711±0.0003h, 0.37±0.02m; 787 Moskva: 6.056±0.001h, 0.61±0.02m; 839 Valborg: 10.366±0.005h, 0.14±0.02m; 912 Maritima: 48.43±0.05h, >0.12±0.02m; 1176 Lucidor: 4.0791±0.0006h, 0.06±0.02m; 1862 Apollo: 3.0680±0.0002h, 0.30-1.20±0.02m; 2266 Tchaikovsky: 4.883±0.003h, 0.04±0.01m; 2951 Perepadin: 4.7808±0.0001h, 0.60±0.02m; 5108 Lubeck: 8.769±0.003, 0.43±0.02m; (17864) 1998 KK38: 6.56±0.01h, 0.17±0.02m; (18582) 1997 XK9: 114±10h, 0.94±0.02m; (20231) 1997 YK: 48.2±0.1h, >0.22±0.02m. Asteroid 868 Lova was also observed but its long period is only constrained as >24h.

  6. A complete mitochondrial genome sequence of Asian black bear Sichuan subspecies (Ursus thibetanus mupinensis

    Directory of Open Access Journals (Sweden)

    Wan-ru Hou, Yu Chen, Xia Wu, Jin-chu Hu, Zheng-song Peng, Jung Yang, Zong-xiang Tang, Cai-Quan Zhou, Yu-ming Li, Shi-kui Yang, Yu-jie Du, Ling-lu Kong, Zheng-long Ren, Huai-yu Zhang, Su-rong Shuai

    2007-01-01

    Full Text Available We obtained the complete mitochondrial genome of U.thibetanus mupinensis by DNA sequencing based on the PCR fragments of 18 primers we designed. The results indicate that the mtDNA is 16 868 bp in size, encodes 13 protein genes, 22 tRNA genes, and 2 rRNA genes, with an overall H-strand base composition of 31.2% A, 25.4% C, 15.5% G and 27.9% T. The sequence of the control region (CR located between tRNA-Pro and tRNA-Phe is 1422 bp in size, consists of 8.43% of the whole genome, GC content is 51.9% and has a 6bp tandem repeat and two 10bp tandem repeats identified by using the Tandem Repeats Finder. U. thibetanus mupinensis mitochondrial genome shares high similarity with those of three other Ursidae: U. americanus (91.46%, U. arctos (89.25% and U. maritimus (87.66%.

  7. Determination of Sulfamonomethoxine, Sulfamethoxazole and Trimethoprim in Swine Plasma by HPLC%高效液相色谱法同时测定猪血浆中的SMM、SMZ和TMP

    Institute of Scientific and Technical Information of China (English)

    崔艳莉; 周振新; 叶云锋; 陈洪; 盛兰弟

    2003-01-01

    建立了同时测定SMM、SMZ和TMP血药浓度的HPLC方法.采用Waters HPLC系统,Waters ODS2柱,以乙腈∶0.017 mol/L磷酸液(20∶80)为流动相,检测波长230 nm.SMM、SMZ在0.05~10.0 μg/mL范围内线性良好(r=0.99998),TMP在0.01~2.0 μg/mL范围内线性良好(r=0.999 99).平均方法回收率分别为94.5%、98.6%和86.8%.最低血浆检测浓度分别为SMM 0.15 μg/mL、SMZ 0.15 μg/mL、TMP 0.03 μg/mL.该法采血量少,样品预处理简单,检测快速、灵敏.

  8. Validation of the German version of the extended ALS functional rating scale as a patient-reported outcome measure.

    Science.gov (United States)

    Abdulla, Susanne; Vielhaber, Stefan; Körner, Sonja; Machts, Judith; Heinze, Hans-Jochen; Dengler, Reinhard; Petri, Susanne

    2013-09-01

    The revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) is a well-established rating instrument to assess the functional status of ALS patients. A recent innovation was the addition of three further items designed to improve its sensitivity at lower levels of physical function (ALSFRS-Extension, ALSFRS-EX). Neither the ALSFRS-R nor the ALSFRS-EX has been validated in German yet. The aim of the present study was the validation of the German version of a self-administered form of the ALSFRS-EX. Seventy-six patients participated in the study. Psychometric analysis included reliability assessment and factorial analysis. To evaluate convergent validity, correlations between ALSFRS-EX items and the MRC score, spasticity, tongue movement, pulmonary function, ALSAQ-40 and Borg dyspnoea scales (upright and supine) were performed. Internal consistency as measured by Cronbach's alpha (total scale 0.868, subscales 0.690-0.938) and corrected item to total correlations (all above 0.50) was high. Test-retest reliability assessed by Spearman's rho (0.882-0.972) and Cohen's Kappa (0.63-0.92) was also high. Principal component analysis with varimax rotation yielded a four-factor solution accounting for approximately 79% of the variance. Clinical parameters were strongly correlated with respective items and subscores of the ALSFRS-EX (muscle strength 0.568-0.833 p scale including high internal consistency and test-retest reliability as well as excellent convergent validity.

  9. A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

    DEFF Research Database (Denmark)

    Sirima, Sodiomon B; Mordmüller, Benjamin; Milligan, Paul

    2016-01-01

    -value=0.009). In the ITT analysis, age-adjusted VE was 11.3% (95% CI 2.5%, 19%, p-value=0.013). VE was higher in older children. In GMZ2-vaccinated children, the incidence of malaria decreased with increasing vaccine-induced anti-GMZ2 IgG concentration. There were 32 cases of severe malaria (18......BACKGROUND: GMZ2 is a recombinant protein malaria vaccine, comprising two blood-stage antigens of Plasmodium falciparum, glutamate-rich protein and merozoite surface protein 3. We assessed efficacy of GMZ2 in children in Burkina Faso, Gabon, Ghana and Uganda. METHODS: Children 12-60months old were...... children were randomized, 1735 received three doses of vaccine (868 GMZ2, 867 control-vaccine). There were 641 malaria episodes in the GMZ2/Alum group and 720 in the control group. In the ATP analysis, vaccine efficacy (VE), adjusted for age and site was 14% (95% confidence interval [CI]: 3.6%, 23%, p...

  10. Harnessing of corneas captured and processed for transplantation in an ocular tissue bank of North-eastern Brazil

    Directory of Open Access Journals (Sweden)

    Izaura Luzia Silvério Freire

    Full Text Available The aim of this study was to describe the harnessing of corneas captured and processed for transplantation in an ocular tissue bank in north-eastern Brazil. This was a transverse and retrospective study, with a sample group of 612 individuals whose corneas were donated and captured between January/2007 and July/2012. This study was approved by the Research Ethics Committee under number 007.0.294.000-10, and research was based on an instrument consisting of social, demographic and clinical data of the donors. Of the 1209 corneas captured, 868 were used and 341 were discarded. Of the 612 donors, the corneas of 597 (97.5% were captured from both eyes, being that 423 (70.9% of these corneas were used. Further studies are required on the reasons for discarding corneas and clarifications as to the conduct of professionals when processing corneas, considering the increase in the quantity of donors and the elevated number of discarded ocular tissue.

  11. Deep plant-derived carbon storage in Amazonian podzols

    Directory of Open Access Journals (Sweden)

    C. R. Montes

    2010-10-01

    Full Text Available Equatorial podzols are soils characterized by thick sandy horizons overlying more clayey horizons. Organic matter produced in the topsoil is transferred in depth through the sandy horizons and accumulate at the transition, at a depth varying from 1 to more than 3 m, forming deep horizons rich in organic matter (Bh horizons. Although they cover great surfaces in the equatorial zone, these soils are still poorly known. Studying podzols from Amazonia, we found out that the deep Bh horizons in poorly drained podzol areas have a thickness higher than 1 m and store unexpected amounts of carbon. The average for the studied area was 66.7 ± 5.8 kg C m−2 for the deep Bh and 86.8 ± 7.1 kg C m−2 for the whole profile. Extrapolating to the podzol areas of the whole Amazonian Basin has been possible thanks to digital maps, giving an order of magnitude around 13.6 ± 1.1 Pg C, at least 12.3 Pg C higher than previous estimates. This assessment should be refined by additional investigations, not only in Amazonia but in all equatorial areas where podzols have been identified. Because of the lack of knowledge on the quality and behaviour of the podzol organic matter, the question of the feedback between the climate and the equatorial podzol carbon cycle is open.

  12. Predicting Unsuccessful Electrical Cardioversion for Acute Atrial Fibrillation (from the AF-CVS Score)

    DEFF Research Database (Denmark)

    Jaakkola, Samuli; Lip, Gregory Y H; Biancari, Fausto;

    2017-01-01

    Electrical cardioversion (ECV) is the standard treatment for acute atrial fibrillation (AF), but identification of patients with increased risk of ECV failure or early AF recurrence is of importance for rational clinical decision-making. The objective of this study was to derive and validate...... a clinical risk stratification tool for identifying patients at high risk for unsuccessful outcome after ECV for acute AF. Data on 2,868 patients undergoing 5,713 ECVs of acute AF in 3 Finnish hospitals from 2003 through 2010 (the FinCV study data) were included in the analysis. Patients from western (n = 3......-measures model in the derivation data set. A multivariate analysis for prediction of the composite end point resulted in identification of 5 clinical variables for increased risk: Age (odds ratio [OR] 1.31, confidence interval [CI] 1.13 to 1.52), not the First AF (OR 1.55, CI 1.19 to 2.02), Cardiac failure (OR 1...

  13. Maxillary sinus lift surgery-with or without graft material? A systematic review.

    Science.gov (United States)

    Silva, L deF; de Lima, V N; Faverani, L P; de Mendonça, M R; Okamoto, R; Pellizzer, E P

    2016-12-01

    The purpose of this systematic review was to perform a comparative analysis of the use or not of graft material in maxillary sinus lift surgery. Relevant studies published in the last 10 years were identified through a search of the PubMed/MEDLINE, ScienceDirect, and Cochrane Library databases and were assessed against the study inclusion and exclusion criteria. The initial search resulted in 1037 articles. After applying the inclusion and exclusion criteria, 16 articles remained. Four hundred and thirty-six patients were followed up over a postoperative period ranging from 6 months to 11 years. In total, 868 implants were installed in 397 maxillary sinuses. The implant survival rate was 96.00% for surgeries performed without graft material and 99.60% for those in which biomaterial was used, within a follow-up period of 48 to 60 months. In conclusion, maxillary sinus lift surgery, with or without graft material, is a safe procedure with a low complication rate and predictable results.

  14. Improved postprandial glycaemic control with insulin Aspart in type 2 diabetic patients treated with insulin

    DEFF Research Database (Denmark)

    Rosenfalck, A M; Thorsby, P; Kjems, L;

    2000-01-01

    The effect on postprandial blood glucose control of an immediately pre-meal injection of the rapid acting insulin analogue Aspart (IAsp) was compared with that of human insulin Actrapid injected immediately or 30 minutes before a test meal in insulin-treated type 2 diabetic patients with residual....../kg) immediately (Act0) or 30 minutes before (Act-30) a test meal. We studied 25 insulin-requiring type 2 diabetic patients, including 14 males and 11 females, with a mean age of 59.7 years (range, 43-71), body mass index 28.3 kg/m2 (range, 21.9-35.0), HbA1c 8.5% (range, 6.8-10.0), glucagon-stimulated C-peptide 1...... between IAsp, administered with a meal and Actrapid injected 30 minutes before the meal (AUCglucose IAsp, 899 +/- 609 mmol/l min vs. Act-30, 868 +/- 374 mmol/l min; Cmax IAsp, 10.8 +/- 2.2 mmol/l vs. Act-30, 11.1 +/- 1.8 mmol/l). No concerns about the safety of IAsp were raised. Immediate pre...

  15. Radon emanation from low-grade uranium ore.

    Science.gov (United States)

    Sahu, Patitapaban; Mishra, Devi Prasad; Panigrahi, Durga Charan; Jha, Vivekanand; Patnaik, R Lokeswara

    2013-12-01

    Estimation of radon emanation in uranium mines is given top priority to minimize the risk of inhalation exposure due to short-lived radon progeny. This paper describes the radon emanation studies conducted in the laboratory as well as inside an operating underground uranium mine at Jaduguda, India. Some of the important parameters, such as grade/(226)Ra activity, moisture content, bulk density, porosity and emanation fraction of ore, governing the migration of radon through the ore were determined. Emanation from the ore samples in terms of emanation rate and emanation fraction was measured in the laboratory under airtight condition in glass jar. The in situ radon emanation rate inside the mine was measured from drill holes made in the ore body. The in situ(222)Rn emanation rate from the mine walls varied in the range of 0.22-51.84 × 10(-3) Bq m(-2) s(-1) with the geometric mean of 8.68 × 10(-3) Bq m(-2) s(-1). A significant positive linear correlation (r = 0.99, p 222)Rn emanation rate and the ore grade was observed. The emanation fraction of the ore samples, which varied in the range of 0.004-0.089 with mean value of 0.025 ± 0.02, showed poor correlation with ore grade and porosity. Empirical relationships between radon emanation rate and the ore grade/(226)Ra were also established for quick prediction of radon emanation rate from the ore body.

  16. Anti-phytopathogen potential of endophytic actinobacteria isolated from tomato plants (Lycopersicon esculentum) in southern Brazil, and characterization of Streptomyces sp. R18(6), a potential biocontrol agent.

    Science.gov (United States)

    de Oliveira, Margaroni Fialho; da Silva, Mariana Germano; Van Der Sand, Sueli T

    2010-09-01

    Tomato plants (Lycopersicon esculentum) are highly susceptible to phytopathogen attack. The resulting intensive application of pesticides on tomato crops can affect the environment and health of humans and animals. The objective of this study was to select potential biocontrol agents among actinobacteria from tomato plants, in a search for alternative phytopathogen control. We evaluated 70 endophytic actinobacteria isolated from tomato plants in southern Brazil, testing their antimicrobial activity, siderophore production, indoleacetic acid production, and phosphate solubility. The actinomycete isolate with the highest antimicrobial potential was selected using the agar-well diffusion method, in order to optimize conditions for the production of compounds with antimicrobial activity. For this study, six growth media (starch casein-SC, ISP2, Bennett's, Sahin, Czapek-Dox, and TSB), three temperatures (25 degrees C, 30 degrees C, and 35 degrees C) and different pH were tested. Of the actinobacteria tested, 88.6% showed antimicrobial activity against at least one phytopathogen, 72.1% showed a positive reaction for indoleacetic acid production, 86.8% produced siderophores and 16.2% showed a positive reaction for phosphate solubility. Isolate R18(6) was selected due to its antagonistic activity against all phytopathogenic microorganisms tested in this study. The best conditions for production were observed in the SC medium, at 30 degrees C and pH 7.0. The isolate R18(6) showed close biochemical and genetic similarity to Streptomyces pluricolorescens.

  17. Synthesis and Crystal Structure of Dinuclear Cadmium Complex [Cd2(phen)4(fca)2](ClO4)2·(H2O)2

    Institute of Scientific and Technical Information of China (English)

    YANG Jia-Xiang; ZHANG Ze; WU Jie-Ying; TIAN Yu-Peng; DU Peng; LIU Qing-Liang; FUN Hoong Kun; C. Suchada

    2003-01-01

    A novel complex [Cd2(phen)4(fca)2](ClO4)2((H2O)2 (fca = dianion of 3-ferrocenyl- 2-crotonic acid, phen = 1,10-phenanthroline) has been synthesized and characterized by X-ray single-crystal structure analysis. It crystallizes in triclinic system, space group Pī with a = 11.6297(5), b = 12.5165(5), c = 13.8986(6) A, α = 63.345(1), β = 87.747(1), γ = 71.862(1)°, V = 1706.20(1) A3, Z = 1, Dc = 1.673 g/cm3, F(000) = 868 and μ(MoKα) = 1.185 mm-1 (λ = 0.71073 A). R = 0.0800 and Wr = 0.1793 for 7653 observed reflections (I > 2σ(I)). The structure consists of a dinuclear cation [Cd2(phen)4(fca)2]2+, two discrete perchlorate anions and two water molecules. The cationic part of the complex shows a tetrametallic core in which two fca groups act as the (O, O') bridging ligands between two cadmium(Ⅱ) ions with a distorted octahedral environment. The Cd…Cd intradimer distance is 4.128 A.

  18. The Genetic Response to Short-term Interventions Affecting Cardiovascular Function: Rationale and Design of the HAPI Heart Study

    Science.gov (United States)

    Mitchell, Braxton D.; McArdle, Patrick F.; Shen, Haiqing; Rampersaud, Evadnie; Pollin, Toni I.; Bielak, Lawrence F.; Jaquish, Cashell; Douglas, Julie A.; Roy-Gagnon, Marie-Hélène; Sack, Paul; Naglieri, Rosalie; Hines, Scott; Horenstein, Richard B.; Chang, Yen-Pei C.; Post, Wendy; Ryan, Kathleen A.; Brereton, Nga Hong; Pakyz, Ruth E.; Sorkin, John; Damcott, Coleen M.; O’Connell, Jeffrey R.; Mangano, Charles; Corretti, Mary; Vogel, Robert; Herzog, William; Weir, Matthew R.; Peyser, Patricia A.; Shuldiner, Alan R.

    2008-01-01

    Background The etiology of cardiovascular disease (CVD) is multifactorial. Efforts to identify genes influencing CVD risk have met with limited success to date, likely due to the small effect sizes of common CVD risk alleles and the presence of gene by gene and gene by environment interactions. Methods The Heredity and Phenotype Intervention (HAPI) Heart Study was initiated in 2002 to measure the cardiovascular response to four short-term interventions affecting cardiovascular risk factors and to identify the genetic and environmental determinants of these responses. The measurements included blood pressure responses to the cold pressor stress test and to a high salt diet, triglyceride excursion in response to a high fat challenge, and response in platelet aggregation to aspirin therapy. Results The interventions were carried out in 868 relatively healthy Amish adults from large families. The heritabilities of selected response traits for each intervention ranged from 8–38%, suggesting that some of the variation associated with response to each intervention can be attributed to the additive effects of genes. Conclusions Identifying these response genes may identify new mechanisms influencing CVD and may lead to individualized preventive strategies and improved early detection of high-risk individuals. PMID:18440328

  19. Richness and diversity of sand flies (Diptera, Psychodidae) in an Atlantic rainforest reserve in southeastern Brazil.

    Science.gov (United States)

    Pinto, Israel Souza; Dos Santos, Claudiney Biral; Ferreira, Adelson Luiz; Falqueto, Aloísio

    2010-12-01

    Our objective was to study and evaluate the richness and diversity of Phlebotominae fauna in the Duas Bocas Biological Reserve (DBBR) in the state of Espírito Santo, in southeastern Brazil. Sand fly collections were carried out during four consecutive nights each month between August 2007 and July 2008 at DBBR by using CDC automatic light traps and an illuminated Shannon trap. Specific richness (S) and Shannon diversity index (H) was calculated for each trap. We collected 18,868 sand flies belonging to 29 species and 13 genera. Nyssomyia yuilli yuilli was the most abundant species followed by Psychodopygus ayrozai, Ps. hirsutus, Psathyromyia pascalei, and Ps. matosi. We recorded Brumptomyia cardosoi, Br. troglodytes, and Ps. geniculatus for the first time in the state of Espírito Santo. We discuss the differences in diversity and richness of the sand flies in both traps and in relation to other Brazilian localities and biomes. We also discuss the possibility of wild transmission of Leishmania in the DBBR and the influence of the sand fly species in leishmaniasis transmission to the adjacent areas of the reserve.

  20. Species-Level Differences in Hyperspectral Metrics among Tropical Rainforest Trees as Determined by a Tree-Based Classifier

    Directory of Open Access Journals (Sweden)

    Dar A. Roberts

    2012-06-01

    Full Text Available This study explores a method to classify seven tropical rainforest tree species from full-range (400–2,500 nm hyperspectral data acquired at tissue (leaf and bark, pixel and crown scales using laboratory and airborne sensors. Metrics that respond to vegetation chemistry and structure were derived using narrowband indices, derivative- and absorption-based techniques, and spectral mixture analysis. We then used the Random Forests tree-based classifier to discriminate species with minimally-correlated, importance-ranked metrics. At all scales, best overall accuracies were achieved with metrics derived from all four techniques and that targeted chemical and structural properties across the visible to shortwave infrared spectrum (400–2500 nm. For tissue spectra, overall accuracies were 86.8% for leaves, 74.2% for bark, and 84.9% for leaves plus bark. Variation in tissue metrics was best explained by an axis of red absorption related to photosynthetic leaves and an axis distinguishing bark water and other chemical absorption features. Overall accuracies for individual tree crowns were 71.5% for pixel spectra, 70.6% crown-mean spectra, and 87.4% for a pixel-majority technique. At pixel and crown scales, tree structure and phenology at the time of image acquisition were important factors that determined species spectral separability.

  1. Subunit structure of karatasin, the proteinase isolated from Bromelia plumieri (karatas).

    Science.gov (United States)

    Montes, C; Amador, M; Cuevas, D; Cordoba, F

    1990-01-01

    Close to 15% of the karatasin proteinase activity in the fruit juice of Bromelia plumieri (karatas) is present outside dialysis Visking tubing in 7 days in 0.2 M acetate buffer (pH) 3.5 or 6.5) containing phenyl mercuric acetate. The small proteinase(s), distinct from the 85% activity in juice due to nondialysable karatasin with a reported Mr of 24,868, separates across Spectrapore (13 kDa) membranes but not across Spectrapore with 3.5 kDa average pore diameter. The dialyzed proteinase is named karatasin-D (K-D). Purified non-Dialysable karatasin can be dissociated to what seems to be K-D by incubation in a buffer solution, containing SDS and 2-mercaptoethanol with phenyl mercuric acetate, in dialysis experiments for 8 days at room temperature using Spectrapore 13 kDa tubing. Thus, native karatasin in B. plumieri fruit juice seem to be the result of association of 2 small molecular mass K-D subunits, linked together by disulfide bonds and electrostatic forces, in equilibrium with small amounts of free K-D molecules. The amino acid composition and partial sequence of karatasin up to the 14th position from the amino terminus have discrete analogies with papain and with stem bromelain.

  2. The Effect of Annealing on Nanothick Indium Tin Oxide Transparent Conductive Films for Touch Sensors

    Directory of Open Access Journals (Sweden)

    Shih-Hao Chan

    2015-01-01

    Full Text Available This study aims to discuss the sheet resistance of ultrathin indium tin oxide (ITO transparent conductive films during the postannealing treatment. The thickness of the ultrathin ITO films is 20 nm. They are prepared on B270 glass substrates at room temperature by a direct-current pulsed magnetron sputtering system. Ultrathin ITO films with high sheet resistance are commonly used for touch panel applications. As the annealing temperature is increased, the structure of the ultrathin ITO film changes from amorphous to polycrystalline. The crystalline of ultrathin ITO films becomes stronger with an increase of annealing temperature, which further leads to the effect of enhanced Hall mobility. A postannealing treatment in an atmosphere can enhance the optical transmittance owing to the filling of oxygen vacancies, but the sheet resistance rises sharply. However, a higher annealing temperature, above 250°C, results in a decrease in the sheet resistance of ultrathin ITO films, because more Sn ions become an effective dopant. An optimum sheet resistance of 336 Ω/sqr was obtained for ultrathin ITO films at 400°C with an average optical transmittance of 86.8% for touch sensor applications.

  3. Traffic-related air pollution exposure and incidence of stroke in four cohorts from Stockholm.

    Science.gov (United States)

    Korek, Michal J; Bellander, Tom D; Lind, Tomas; Bottai, Matteo; Eneroth, Kristina M; Caracciolo, Barbara; de Faire, Ulf H; Fratiglioni, Laura; Hilding, Agneta; Leander, Karin; Magnusson, Patrik K E; Pedersen, Nancy L; Östenson, Claes-Göran; Pershagen, Göran; Penell, Johanna C

    2015-01-01

    We investigated the risk of stroke related to long-term ambient air pollution exposure, in particular the role of various exposure time windows, using four cohorts from Stockholm County, Sweden. In total, 22,587 individuals were recruited from 1992 to 2004 and followed until 2011. Yearly air pollution levels resulting from local road traffic emissions were assessed at participant residences using dispersion models for particulate matter (PM10) and nitrogen oxides (NOX). Cohort-specific hazard ratios were estimated for time-weighted air pollution exposure during different time windows and the incidence of stroke, adjusted for common risk factors, and then meta-analysed. Overall, 868 subjects suffered a non-fatal or fatal stroke during 238,731 person-years of follow-up. An increment of 20 μg/m(3) in estimated annual mean of road-traffic related NOX exposure at recruitment was associated with a hazard ratio of 1.16 (95% CI 0.83-1.61), with evidence of heterogeneity between the cohorts. For PM10, an increment of 10 μg/m(3) corresponded to a hazard ratio of 1.14 (95% CI 0.68-1.90). Time-window analyses did not reveal any clear induction-latency pattern. In conclusion, we found suggestive evidence of an association between long-term exposure to NOX and PM10 from local traffic and stroke at comparatively low levels of air pollution.

  4. Dento-alveolar and maxillofacial injuries - a survey of knowledge of the regimental aid providers in the Israeli army.

    Science.gov (United States)

    Levin, Liran; Lin, Shaul; Emodi, Omri; Gordon, Moshe; Peled, Micha

    2007-08-01

    The present study evaluated the knowledge of physicians and emergency medical technicians (EMT) regarding primary treatment for oral and maxillofacial trauma and assessed the experience they have in treating oral and maxillofacial injuries. The study population consisted of 80 military physicians and EMT during their military service. A questionnaire was distributed relating to demographic data such as age, gender, position, and type of military service, as well as past experience in treating or witnessing oral and maxillofacial trauma, former education regarding diagnosis and treatment of oral and maxillofacial trauma, assessment of knowledge regarding oral and maxillofacial trauma, etc. The questionnaire was answered by 76 participants (95% response rate): 32 physicians and 44 EMT. Only 17 (22.4%) received education regarding oral and maxillofacial trauma (eight physicians, 25% and nine EMT, 20.5%). Nevertheless, 23 (30.3%) reported witnessing such an injury during their military service. Oral and maxillofacial injuries were first seen by the EMT in 43.4% of the cases, a physician in 23.7%, and a dentist in only 9.2%. Overall, 66 (86.8%) of the physicians and EMT stated that it was important to educate the primary health care providers regarding diagnosis and treatment of oral and maxillofacial trauma. Special emphasis should be given to providing primary caregivers with the relevant education to improve their knowledge and ability of dealing with diagnosis and treatment of oral and maxillofacial trauma.

  5. An intercomparison of different topography effects on discrimination performance of fuzzy change vector analysis algorithm

    Science.gov (United States)

    Singh, Sartajvir; Talwar, Rajneesh

    2016-12-01

    Detection of snow cover changes is vital for avalanche hazard analysis and flood flashes that arise due to variation in temperature. Hence, multitemporal change detection is one of the practical mean to estimate the snow cover changes over larger area using remotely sensed data. There have been some previous studies that examined how accuracy of change detection analysis is affected by different topography effects over Northwestern Indian Himalayas. The present work emphases on the intercomparison of different topography effects on discrimination performance of fuzzy based change vector analysis (FCVA) as change detection algorithm that includes extraction of change-magnitude and change-direction from a specific pixel belongs multiple or partial membership. The qualitative and quantitative analysis of the proposed FCVA algorithm is performed under topographic conditions and topographic correction conditions. The experimental outcomes confirmed that in change category discrimination procedure, FCVA with topographic correction achieved 86.8% overall accuracy and 4.8% decay (82% of overall accuracy) is found in FCVA without topographic correction. This study suggests that by incorporating the topographic correction model over mountainous region satellite imagery, performance of FCVA algorithm can be significantly improved up to great extent in terms of determining actual change categories.

  6. Analysis of the Two-Regime Method on Square Meshes

    KAUST Repository

    Flegg, Mark B.

    2014-01-01

    The two-regime method (TRM) has been recently developed for optimizing stochastic reaction-diffusion simulations [M. Flegg, J. Chapman, and R. Erban, J. Roy. Soc. Interface, 9 (2012), pp. 859-868]. It is a multiscale (hybrid) algorithm which uses stochastic reaction-diffusion models with different levels of detail in different parts of the computational domain. The coupling condition on the interface between different modeling regimes of the TRM was previously derived for onedimensional models. In this paper, the TRM is generalized to higher dimensional reaction-diffusion systems. Coupling Brownian dynamics models with compartment-based models on regular (square) two-dimensional lattices is studied in detail. In this case, the interface between different modeling regimes contains either flat parts or right-angle corners. Both cases are studied in the paper. For flat interfaces, it is shown that the one-dimensional theory can be used along the line perpendicular to the TRM interface. In the direction tangential to the interface, two choices of the TRM parameters are presented. Their applicability depends on the compartment size and the time step used in the molecular-based regime. The two-dimensional generalization of the TRM is also discussed in the case of corners. © 2014 Society for Industrial and Applied Mathematics.

  7. Identification and developmental expression profiling of putative alkaloid biosynthetic genes in Corydalis yanhusuo bulbs.

    Science.gov (United States)

    Liao, Dengqun; Wang, Pengfei; Jia, Chan; Sun, Peng; Qi, Jianjun; Zhou, Lili; Li, Xian'en

    2016-01-18

    Alkaloids in bulbs of Corydalis (C.) yanhusuo are the major pharmacologically active compounds in treatment of blood vessel diseases, tumors and various pains. However, due to the absence of gene sequences in C. yanhusuo, the genes involved in alkaloid biosynthesis and their expression during bulb development remain unknown. We therefore established the first transcriptome database of C. yanhusuo via Illumina mRNA-Sequencing of a RNA composite sample collected at Bulb initiation (Day 0), early enlargement (Day 10) and maturation (Day 30). 25,013,630 clean 90 bp paired-end reads were de novo assembled into 47,081 unigenes with an average length of 489 bp, among which 30,868 unigenes (65.56%) were annotated in four protein databases. Of 526 putative unigenes involved in biosynthesis o f various alkaloids, 187 were identified as the candidate genes involved in the biosynthesis of benzylisoquinoline alkaloids (BIAs), the only alkaloid type reported in C. yanhusuo untill now. BIAs biosynthetic genes were highly upregulated in the overall pathway during bulb development. Identification of alkaloid biosynthetic genes in C. yanhusuo provide insights on pathways and molecular regulation of alkaloid biosynthesis, to initiate metabolic engineering in order to improve the yield of interesting alkaloids and to identify potentially new alkaloids predicted from the transcriptomic information.

  8. Alternatives to polysomnography (PSG): a validation of wrist actigraphy and a partial-PSG system.

    Science.gov (United States)

    Kosmadopoulos, Anastasi; Sargent, Charli; Darwent, David; Zhou, Xuan; Roach, Gregory D

    2014-12-01

    The objective of this study was to assess the validity of a sleep/wake activity monitor, an energy expenditure activity monitor, and a partial-polysomnography system at measuring sleep and wake under identical conditions. Secondary aims were to evaluate the sleep/wake thresholds for each activity monitor and to compare the three devices. To achieve these aims, two nights of sleep were recorded simultaneously with polysomnography (PSG), two activity monitors, and a partial-PSG system in a sleep laboratory. Agreement with PSG was evaluated epoch by epoch and with summary measures including total sleep time (TST) and wake after sleep onset (WASO). All of the devices had high agreement rates for identifying sleep and wake, but the partial-PSG system was the best, with an agreement of 91.6% ± 5.1%. At their best thresholds, the sleep/wake monitor (medium threshold, 87.7% ± 7.6%) and the energy expenditure monitor (very low threshold, 86.8% ± 8.6%) had similarly high rates of agreement. The summary measures were similar to those determined by PSG, but the partial-PSG system provided the most consistent estimates. Although the partial-PSG system was the most accurate device, both activity monitors were also valid for sleep estimation, provided that appropriate thresholds were selected. Each device has advantages, so the primary consideration for researchers will be to determine which best suits a given research design.

  9. Effect of thermal and alkaline pretreatment of giant miscanthus and Chinese fountaingrass on biogas production.

    Science.gov (United States)

    Nkemka, Valentine Nkongndem; Li, Yongqiang; Hao, Xiying

    2016-01-01

    Giant miscanthus (Miscanthus × giganteus) and Chinese fountaingrass (Pennisetum alopecuroides (L.) Spreng), cultivated for landscaping and soil conservation, are potential energy crops. The study investigated the effect of combined thermal and alkaline pretreatments on biogas production of these energy crops. The pretreatment included two types of alkali (6% CaO and 6% NaOH) at 22, 70 and 100 °C. The alkaline pretreatment resulted in a greater breakdown of the hemicellulose fraction, with CaO more effective than NaOH. Pretreatment of giant miscanthus with 6% CaO at 100 °C for 24 h produced a CH4 yield (313 mL g(-1) volatile solids (VS)) that was 1.7 times that of the untreated sample (186 mL g(-1) VS). However, pretreatment of Chinese fountaingrass with 6% CaO or 6% NaOH at 70 °C for 24 h resulted in similar CH4 yields (328 and 302 mL g(-1) VS for CaO and NaOH pretreatments) as the untreated sample (311 mL g(-1) VS). Chinese fountaingrass was more easily digestible but had a low overall CH4 yield per hectare (1,831 m(3) ha(-1) y(-1)) compared to giant miscanthus (6,868 m(3) ha(-1) y(-1)). This study demonstrates the potential of thermal/alkaline pretreatment and the use of giant miscanthus and Chinese fountaingrass for biogas production.

  10. The Study of The Red Dry Pepper High Yeild Optimization of Ertilization Experiment%红干椒高产优化施肥试验研究

    Institute of Scientific and Technical Information of China (English)

    张振刚; 张慧敏; 马彦鹏; 李志刚; 陈传梅; 赵达

    2012-01-01

    为了探究适合红干椒高产的氮、磷、钾肥的最佳配比,在初步明确不同量的氮肥、磷肥、钾肥三种肥的红干椒小区产量的前提下,采用二次正交旋转组合设计法探讨3个因素(N、P、K)对红干椒产量的影响.结果表明:在试验用量的范围内,氮在-0.264水平(0.04752kg),磷在-0.868水平(0.11718kg),钾在1水平(0.405kg)时产量达到最大值,三因素达到最优水平.%The study aim to investigate the best ratio of nitrogen,phosphorus and potassium for the high yeild of red dry peper.The effect on Plot yeilds of the peper in different dossage of nitrogen,phosphorus and potassium is analysized by three factors(N,P,K)quadri-rotation orthogonal experiments.The results showed the best harvest and the optimum level of three factors at the nitrogen concentration of 0.264,Pof 0.869and Pof 0.11718.

  11. Stillbirth history and Toxoplasma gondii infection in women attending public health centers in a northern Mexican City

    Science.gov (United States)

    Alvarado-Esquivel, C.; Pacheco-Vega, S. J.; Salcedo-Jaquez, M.; Sánchez-Anguiano, L. F.; Hernández-Tinoco, J.; Rábago-Sánchez, E.; Centeno-Tinoco, M. M.; Flores-Garcia, I. D.; Ramos-Nevarez, A.; Cerrillo-Soto, S. M.; Guido-Arreola, C. A.; Beristain-García, I.; Liesenfeld, O.; Berumen-Segovia, L. O.; Saenz-Soto, L.; Sifuentes-Álvarez, A.

    2015-01-01

    Through a cross-sectional study design, 150 women attending public health centers with a history of stillbirths were examined for anti-Toxoplasma gondii IgG and IgM antibodies in Durango City, Mexico. Bivariate and multivariate analyses were used to assess the association of T. gondii seropositivity with the characteristics of the women with stillbirth history. Of the 150 women (mean age: 32.09 ± 9.16 years) studied, 14 (9.3%) had anti-T. gondii IgG antibodies and six (42.9%) of them were also positive for anti-T. gondii IgM antibodies. Multivariate analysis showed that T. gondii seropositivity was associated with high frequency (4–7 days a week) of eating meat (OR = 5.52; 95% CI: 1.48–20.59; P = 0.01), history of lymphadenopathy (OR = 4.52; 95% CI: 1.14–17.82; P = 0.03), and history of surgery (OR = 8.68; 95% CI: 1.04–72.15; P = 0.04). This is the first study on the seroepidemiology of T. gondii infection in women with a history of stillbirths in Mexico. The association of T. gondii exposure with a history of surgery warrants for further research. Risk factors for T. gondii infection found in the present survey may help to design optimal educational programs to avoid T. gondii infection. PMID:26185685

  12. A batch-fabricated electret-biased wideband MEMS vibration energy harvester with frequency-up conversion behavior powering a UHF wireless sensor node

    Science.gov (United States)

    Lu, Y.; O'Riordan, E.; Cottone, F.; Boisseau, S.; Galayko, D.; Blokhina, E.; Marty, F.; Basset, P.

    2016-12-01

    This paper reports a batch-fabricated, low-frequency and wideband MEMS electrostatic vibration energy harvester (e-VEH), which implements corona-charged vertical electrets and nonlinear elastic stoppers. A numeric model is used to perform parametric study, where we observe a wideband bi-modality resulting from nonlinearity. The nonlinear stoppers improve the bandwidth and induce a frequency-up feature at low frequencies. When the e-VEH works with a bias of 45 V, the power reaches a maximum value of 6.6 μW at 428 Hz and 2.0 g rms, and is above 1 μW at 50 Hz. When the frequency drops below 60 Hz, a ‘frequency-up’ conversion behavior is observed with peaks of power at 34 Hz and 52 Hz. The  -3 dB bandwidth is more than 60% of its central frequency, both including and excluding the hysteresis introduced by the nonlinear stoppers. We also perform experiments with wideband Gaussian noise. The device is eventually tested with an RF data transmission setup, where a communication node with an internal temperature sensor is powered. Every 2 min, a data transmission at 868 MHz is performed by the sensor node supplied by the e-VEH, and received at a distance of up to 15 m.

  13. Circulating levels of vitamin D and colon and rectal cancer: the Physicians' Health Study and a meta-analysis of prospective studies.

    Science.gov (United States)

    Lee, Jung Eun; Li, Haojie; Chan, Andrew T; Hollis, Bruce W; Lee, I-Min; Stampfer, Meir J; Wu, Kana; Giovannucci, Edward; Ma, Jing

    2011-05-01

    It remains unknown whether increased risk with low levels of vitamin D is present for colon and/or rectal cancer. To investigate the association between circulating vitamin D levels and colon and rectal cancer, we examined the associations between plasma levels of 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)2D] and colon and rectal cancer in the Physicians' Health Study and then conducted a meta-analysis of eight prospective studies of circulating levels of 25(OH)D and colon and rectal cancers, including the Physicians' Health Study. Study-specific ORs and 95% CIs were pooled by using a random-effects model. A total of 1,822 colon and 868 rectal cancers were included in the meta-analysis. We observed a significant inverse association for colorectal cancer (OR = 0.66; 95% CI, 0.54-0.81), comparing top versus bottom quantiles of circulating 25(OH)D levels. The inverse association was stronger for rectal cancer (OR = 0.50 for top versus bottom quantiles; 95% CI, 0.28-0.88) than colon cancer (OR = 0.77; 95% CI, 0.56-1.07; P value for difference between colon and rectal cancer = 0.20). These data suggest an inverse association between circulating 25(OH)D levels and colorectal cancer, with a stronger association for rectal cancer.

  14. CHARACTERISTICS OF PATIENTS WITH CEREBRAL STROKE OR TRANSIENT ISCHEMIC ATTACK, INCLUDED INTO THE LIS-2 REGISTER (LYUBERTSY STUDY OF MORTALITY IN PATIENTS AFTER STROKE

    Directory of Open Access Journals (Sweden)

    S. Yu. Martsevich

    2015-01-01

    Full Text Available Aim. To provide final data on the three-year period of the inclusion of patients; to give most accurate "portrait" of patients hospitalized with a brain stroke within the framework of the LIS-2 register (Lyubertsy study of mortality in patients after stroke.Material and methods. All patients (n=960 admitted to the Lyubertsy district hospital №2 with stroke for the period from 01.2009 to 12.2011 were included into the study.Results. Men accounted for 37.5%, women - 62.5%, mean age was 71.1±9.8 years. The history of hypertension was present in 833 patients (86.8%, atrial fibrillation in 252 (26.8% patients, 199 (20.7% patients had previously undergone stroke. In-hospital mortality was 21.6% (207 patients had died; mean age 72.9±9.8 years. Low frequency of the antihypertensive therapy (34.5%, lipid-lowering therapy (0.7%, antiplatelet agents (5.7%, anticoagulation therapy prescription in patients with atrial fibrillation was detected.Conclusion. Insufficient assignment of drugs with a proven effect on the prognosis in patients with risk factors prior to the development of the reference stroke draws attention. High incidence of recurrent strokes indicates an underactive secondary prevention.

  15. Algorithms for Recollection of Search Terms Based on the Wikipedia Category Structure

    Directory of Open Access Journals (Sweden)

    Stijn Vandamme

    2014-01-01

    Full Text Available The common user interface for a search engine consists of a text field where the user can enter queries consisting of one or more keywords. Keyword query based search engines work well when the users have a clear vision what they are looking for and are capable of articulating their query using the same terms as indexed. For our multimedia database containing 202,868 items with text descriptions, we supplement such a search engine with a category-based interface whose category structure is tailored to the content of the database. This facilitates browsing and offers the users the possibility to look for named entities, even if they forgot their names. We demonstrate that this approach allows users who fail to recollect the name of named entities to retrieve data with little effort. In all our experiments, it takes 1 query on a category and on average 2.49 clicks, compared to 5.68 queries on the database’s traditional text search engine for a 68.3% success probability or 6.01 queries when the user also turns to Google, for a 97.1% success probability.

  16. Detection of Greenhouse Gas Precursors from Diesel Engines Using Electrochemical and Photoacoustic Sensors

    Directory of Open Access Journals (Sweden)

    Aline Rocha

    2010-11-01

    Full Text Available Atmospheric pollution is one of the worst threats to modern society. The consequences derived from different forms of atmospheric pollution vary from the local to the global scale, with deep impacts on climate, environment and human health. Several gaseous pollutants, even when present in trace concentrations, play a fundamental role in important processes that occur in atmosphere. Phenomena such as global warming, photochemical smog formation, acid rain and the depletion of the stratospheric ozone layer are strongly related to the increased concentration of certain gaseous species in the atmosphere. The transport sector significantly produces atmospheric pollution, mainly when diesel oil is used as fuel. Therefore, new methodologies based on selective and sensitive gas detection schemes must be developed in order to detect and monitor pollutant gases from this source. In this work, CO2 Laser Photoacoustic Spectroscopy was used to evaluate ethylene emissions and electrochemical analyzers were used to evaluate the emissions of CO, NOx and SO2 from the exhaust of diesel powered vehicles (rural diesel with 5% of biodiesel, in this paper called only diesel at different engine rotation speeds. Concentrations in the range 6 to 45 ppmV for ethylene, 109 to 1,231 ppmV for carbon monoxide, 75 to 868 ppmV for nitrogen oxides and 3 to 354 ppmV for sulfur dioxide were obtained. The results indicate that the detection techniques used were sufficiently selective and sensitive to detect the gaseous species mentioned above in the ppmV range.

  17. Comparative transcriptome and potential antiviral signaling pathways analysis of the gills in the red swamp crayfish, Procambarus clarkii infected with White Spot Syndrome Virus (WSSV

    Directory of Open Access Journals (Sweden)

    Zhi-Qiang Du

    Full Text Available Abstract Red swamp crayfish is an important model organism for research of the invertebrate innate immunity mechanism. Its excellent disease resistance against bacteria, fungi, and viruses is well-known. However, the antiviral mechanisms of crayfish remain unclear. In this study, we obtained high-quality sequence reads from normal and white spot syndrome virus (WSSV-challenged crayfish gills. For group normal (GN, 39,390,280 high-quality clean reads were randomly assembled to produce 172,591 contigs; whereas, 34,011,488 high-quality clean reads were randomly assembled to produce 182,176 contigs for group WSSV-challenged (GW. After GO annotations analysis, a total of 35,539 (90.01%, 14,931 (37.82%, 28,221 (71.48%, 25,290 (64.05%, 15,595 (39.50%, and 13,848 (35.07% unigenes had significant matches with sequences in the Nr, Nt, Swiss-Prot, KEGG, COG and GO databases, respectively. Through the comparative analysis between GN and GW, 12,868 genes were identified as differentially up-regulated DEGs, and 9,194 genes were identified as differentially down-regulated DEGs. Ultimately, these DEGs were mapped into different signaling pathways, including three important signaling pathways related to innate immunity responses. These results could provide new insights into crayfish antiviral immunity mechanism.

  18. 调Q开关紫翠宝石激光治疗颧部褐青色痣的应用研究%Study on the efficacy of Q-Switched Alexandrite laser in treatment of naevus fusco-caerulens zygomaticus

    Institute of Scientific and Technical Information of China (English)

    尹飞; 于加平; 蔡茂季; 曾金鉴; 王乂

    2006-01-01

    目的观察调Q开关紫翠宝石激光机治疗颧部褐青色痣的临床效果.方法采用美国赛诺秀公司调Q开关闪光灯泵浦紫翠宝石激光机,波长752 nm,选用不同的激光技术参数进行治疗.结果 38例患者均经3~5次治疗,每次间隔2~3个月.经3次治疗9例(23.7%),4次治疗13例(34.2%),5次治疗16例(42.1%).痊愈22例(57.9%),显效11例(28.9%),有效5例(13.2%),无效0,总有效率为86.8%,疗效与治疗次数成正相关.5例出现不同程度的继发性色素沉着,3个月后逐渐消退,所有病例均无瘢痕形成.结论调Q开关紫翠宝石激光机治疗颧部褐青色痣安全有效.

  19. The Relationship between Dental Caries and Some Socio-economic Factors in 35- 44 Years Old Adults in Some Urban Areas of Sistan & Baluchestan

    Directory of Open Access Journals (Sweden)

    Z Abdolazimi

    2012-10-01

    Full Text Available Introduction: In order to improve the oral health, systematic analysis of oral health condition and related factors should be conducted. This study aimed to evaluate dental caries and some related factors in 35-44 years old men & women in five urban areas of Sistan and Baluchestan in 2009-2010. Methods: In this descriptive cross-sectional study, 550 people were chosen by random stratified clustering in five different urban areas of the province. All participants were examined and the DMFT index was determined. Demographic and social information and their oral health behaviors were registered in a questionnaire which was composed of 11 questions. The data were analyzed by SPSS (version 17 and descriptive statistic methods. Results: Statistical analysis showed that average of DMFT was 10.05 ± 7.186. DMFT in females (11.43 ± 7.5 was more than males (8.68 ± 6.6 significantly (P 0.05 Conclusion: Results of this study could be used by public health managers to plan and evaluate public health in the future. With an emphasis on improving high risk patients’ situation, appropriate interventions can be designed to achieve good results in the short and long term

  20. Characterization of resistance gene analogues (RGAs) in apple (Malus × domestica Borkh.) and their evolutionary history of the Rosaceae family.

    Science.gov (United States)

    Perazzolli, Michele; Malacarne, Giulia; Baldo, Angela; Righetti, Laura; Bailey, Aubrey; Fontana, Paolo; Velasco, Riccardo; Malnoy, Mickael

    2014-01-01

    The family of resistance gene analogues (RGAs) with a nucleotide-binding site (NBS) domain accounts for the largest number of disease resistance genes and is one of the largest gene families in plants. We have identified 868 RGAs in the genome of the apple (Malus × domestica Borkh.) cultivar 'Golden Delicious'. This represents 1.51% of the total number of predicted genes for this cultivar. Several evolutionary features are pronounced in M. domestica, including a high fraction (80%) of RGAs occurring in clusters. This suggests frequent tandem duplication and ectopic translocation events. Of the identified RGAs, 56% are located preferentially on six chromosomes (Chr 2, 7, 8, 10, 11, and 15), and 25% are located on Chr 2. TIR-NBS and non-TIR-NBS classes of RGAs are primarily exclusive of different chromosomes, and 99% of non-TIR-NBS RGAs are located on Chr 11. A phylogenetic reconstruction was conducted to study the evolution of RGAs in the Rosaceae family. More than 1400 RGAs were identified in six species based on their NBS domain, and a neighbor-joining analysis was used to reconstruct the phylogenetic relationships among the protein sequences. Specific phylogenetic clades were found for RGAs of Malus, Fragaria, and Rosa, indicating genus-specific evolution of resistance genes. However, strikingly similar RGAs were shared in Malus, Pyrus, and Prunus, indicating high conservation of specific RGAs and suggesting a monophyletic origin of these three genera.

  1. Evaluation of the Dentistry course of UNIVILLE students’ knowledge about the use of the extracted teeth in the graduation and the teeth bank

    Directory of Open Access Journals (Sweden)

    Débora ZUCCO

    2006-05-01

    Full Text Available The aim of this study was, through a questionnaire, evaluate the levelof knowledge of the students from graduation in Dentistry course –UNIVILLE –, about the teeth bank: its activities and functioning,biosecutity in teeth manipulation and, especially, to find out the reason why the students do not donate spontaneously extracted teeth to the bank.A questionnaire was elaborated and applied to the studentsfrom the first to the fifth year of graduation with pertinent questions about the teeth bank, such as the use of teeth in the disciplines of the course, biosecurity and donation of dental elements. After the questionnaire was applied, it was possible to evidence that: all the interviewed students (100% had needed extracted dental elements to use in laboratory assignments; 84,2% have reported difficulty in the obtainment of the requested teeth; about biosecurity, 66.6% of the students have stated that they had already manipulated extracted teeth without individual protection equipment; even knowing that the pulp and periodontal tissues can present sanguineous pathogenic microorganisms transmissible to the human being (86,8%. It was evidenced that the main reason why students did not participate effectively in the donation of “private supplies”, is the unfamiliarity with the activities of the teeth bank, its norms of procedure, protocols of donation and, mainly, the withdrawal of dental elements.

  2. Global pattern analysis and classification of dermoscopic images using textons

    Science.gov (United States)

    Sadeghi, Maryam; Lee, Tim K.; McLean, David; Lui, Harvey; Atkins, M. Stella

    2012-02-01

    Detecting and classifying global dermoscopic patterns are crucial steps for detecting melanocytic lesions from non-melanocytic ones. An important stage of melanoma diagnosis uses pattern analysis methods such as 7-point check list, Menzies method etc. In this paper, we present a novel approach to investigate texture analysis and classification of 5 classes of global lesion patterns (reticular, globular, cobblestone, homogeneous, and parallel pattern) in dermoscopic images. Our statistical approach models the texture by the joint probability distribution of filter responses using a comprehensive set of the state of the art filter banks. This distribution is represented by the frequency histogram of filter response cluster centers called textons. We have also examined other two methods: Joint Distribution of Intensities (JDI) and Convolutional Restricted Boltzmann Machine (CRBM) to learn the pattern specific features to be used for textons. The classification performance is compared over the Leung and Malik filters (LM), Root Filter Set (RFS), Maximum Response Filters (MR8), Schmid, Laws and our proposed filter set as well as CRBM and JDI. We analyzed 375 images of the 5 classes of the patterns. Our experiments show that the joint distribution of color (JDC) in the L*a*b* color space outperforms the other color spaces with a correct classification rate of 86.8%.

  3. Estudo clinicopatológico de 106 adenomas pleomórficos de glândula salivar maior A clinicopathologic study of 106 pleomorphic adenomas of the major salivary glands

    Directory of Open Access Journals (Sweden)

    Jerlucia Cavalcanti das Neves

    2007-10-01

    Full Text Available INTRODUÇÃO: O adenoma pleomórfico (AP é o mais comum dos tumores das glândulas salivares. Transformação maligna pode ocorrer após recorrências ou em casos com longo tempo de evolução. OBJETIVO: Analisar os aspectos clinicoepidemiológicos e anatomopatológicos do AP de glândula salivar maior, principalmente os considerados indício de transformação maligna. MATERIAL E MÉTODO: Foram avaliados 106 casos de AP pela pesquisa retrospectiva nos prontuários clínicos e revisão das preparações histológicas. RESULTADOS: A média de idade dos pacientes foi de 39,51 anos, houve predomínio do sexo feminino (69,5%, a glândula parótida foi a mais acometida (86,8% e o tempo de evolução foi superior a um ano em 76,74% dos casos, com tamanho tumoral de 3,48 cm em média. A avaliação histopatológica demonstrou cápsula tumoral incompleta e delgada em 49% dos casos. Protrusões para a cápsula ou extensão extracapsular foram infreqüentes, 11,32% e 8,49%, respectivamente. A matriz extracelular variou entre mixocondróide (41,5%, mixóide (36,8%, condróide (3,8% e fibrótica (1,9%, tendo sido observadas associações entre os diversos tipos. O componente epitelial/mioepitelial constituiu 50% ou mais do tumor em 65,1% dos casos e estava disposto em arranjos cordonal (86,8%, ductal (81,1%, sólido (40,6%, cístico (20,7% e em "paliçada" (8,49%. Metaplasia escamosa ocorreu em 16,04% dos casos. Alterações histopatológicas relacionadas com transformação maligna foram incomuns: hialinização extensa (4,7% e necrose (0,9%. CONCLUSÕES: confirma-se a diversidade histopatológica do AP. Características associadas a transformação maligna não foram freqüentes na amostra.INTRODUCTION: Pleomorphic adenomas (PA are the most common histologic type of salivary gland tumors. Malignant transformation may occur in the setting of recurrent or longstanding disease. OBJECTIVE: Evaluate the clinicopathologic characteristics of PA of the major

  4. FDG PET/MR for lymph node staging in head and neck cancer

    Energy Technology Data Exchange (ETDEWEB)

    Platzek, Ivan, E-mail: ivan.platzek@uniklinikum-dresden.de [Dresden University Hospital, Department of Radiology, Fetscherstr. 74, 01307 Dresden (Germany); Beuthien-Baumann, Bettina, E-mail: bettina.beuthien-baumann3@uniklinikum-dresden.de [Dresden University Hospital, Department of Nuclear Medicine, Fetscherstr. 74, 01307 Dresden (Germany); Schneider, Matthias, E-mail: m.schneider@mkgdresden.de [Dresden University Hospital, Department of Oral and Maxillofacial Surgery, Fetscherstr. 74, 01307 Dresden (Germany); Gudziol, Volker, E-mail: volker.gudziol@uniklinikum-dresden.de [Dresden University Hospital, Department of Otolaryngology, Fetscherstr. 74, 01307 Dresden (Germany); Kitzler, Hagen H., E-mail: hagen.kitzler@uniklinikum-dresden.de [Dresden University Hospital, Department of Neuroradiology, Fetscherstr. 74, 01307 Dresden (Germany); Maus, Jens, E-mail: j.maus@hzdr.de [Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstr. 400, 01328 Dresden (Germany); Schramm, Georg, E-mail: g.schramm@hzdr.de [Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstr. 400, 01328 Dresden (Germany); Popp, Manuel, E-mail: manuel.popp@praxisklinik-dresden.de [Dresden University Hospital, Department of Nuclear Medicine, Fetscherstr. 74, 01307 Dresden (Germany); Laniado, Michael, E-mail: michael.laniado@uniklinikum-dresden.de [Dresden University Hospital, Department of Radiology, Fetscherstr. 74, 01307 Dresden (Germany); Kotzerke, Jörg, E-mail: Joerg.Kotzerke@uniklinikum-dresden.de [Dresden University Hospital, Department of Nuclear Medicine, Fetscherstr. 74, 01307 Dresden (Germany); Hoff, Jörg van den, E-mail: j.van_den_hoff@hzdr.de [Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstr. 400, 01328 Dresden (Germany)

    2014-07-15

    Objective: To assess the diagnostic value of PET/MR (positron emission tomography/magnetic resonance imaging) with FDG (18F-fluorodeoxyglucose) for lymph node staging in head and neck cancer. Materials and methods: This prospective study was approved by the local ethics committee; all patients signed informed consent. Thirty-eight patients with squamous cell carcinoma of the head and neck region underwent a PET scan on a conventional scanner and a subsequent PET/MR on a whole-body hybrid system after a single intravenous injection of FDG. The accuracy of PET, MR and PET/MR for lymph node metastases were compared using receiver operating characteristic (ROC) analysis. Histology served as the reference standard. Results: Metastatic disease was confirmed in 16 (42.1%) of 38 patients and 38 (9.7%) of 391 dissected lymph node levels. There were no significant differences between PET/MR, MR and PET and MR (p > 0.05) regarding accuracy for cervical metastatic disease. Based on lymph node levels, sensitivity and specificity for metastatic involvement were 65.8% and 97.2% for MR, 86.8% and 97.0% for PET and 89.5% and 95.2% for PET/MR. Conclusions: In head and neck cancer, FDG PET/MR does not significantly improve accuracy for cervical lymph node metastases in comparison to MR or PET.

  5. Potential Vaccine Targets against Rabbit Coccidiosis by Immunoproteomic Analysis.

    Science.gov (United States)

    Song, Hongyan; Dong, Ronglian; Qiu, Baofeng; Jing, Jin; Zhu, Shunxing; Liu, Chun; Jiang, Yingmei; Wu, Liucheng; Wang, Shengcun; Miao, Jin; Shao, Yixiang

    2017-02-01

    The aim of this study was to identify antigens for a vaccine or drug target to control rabbit coccidiosis. A combination of 2-dimensional electrophoresis, immunoblotting, and mass spectrometric analysis were used to identify novel antigens from the sporozoites of Eimeria stiedae. Protein spots were recognized by the sera of New Zealand rabbits infected artificially with E. stiedae. The proteins were characterized by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF/TOF-MS) analysis in combination with bioinformatics. Approximately 868 protein spots were detected by silver-staining, and a total of 41 immunoreactive protein spots were recognized by anti-E. stiedae sera. Finally, 23 protein spots were successfully identified. The proteins such as heat shock protein 70 and aspartyl protease may have potential as immunodiagnostic or vaccine antigens. The immunoreactive proteins were found to possess a wide range of biological functions. This study is the first to report the proteins recognized by sera of infected rabbits with E. stiedae, which might be helpful in identifying potential targets for vaccine development to control rabbit coccidiosis.

  6. Impacts of Human Activities on the Occurrence of Groundwater Nitrate in an Alluvial Plain: A Multiple Isotopic Tracers Approach

    Institute of Scientific and Technical Information of China (English)

    Zhonghe Pang; Lijuan Yuan; Tianming Huang; Yanlong Kong; Jilai Liu; Yiman Li

    2013-01-01

    Nitrate pollution is a severe problem in areas with intensive agricultural activities.This study focuses on nitrate occurrence and its constraints in a selected alluvial fan using chemical data combined with environmental isotopic tracers (18O,3H,and 15N).Results show that groundwater nitrate in the study area is as high as 258.0 mg/L (hereafter NO3-) with an average of 86.8 mg/L against national drinking water limit of 45 mg/L and a regional baseline value of 14.4 mg/L.Outside of the riparian zone,nitrate occurrence is closely related to groundwater circulation and application of chemical fertilizer.High groundwater nitrate is found in the recharge area,where nitrate enters into groundwater through vertical infiltration,corresponding to high 3H and enriched 18O in the water.In the riparian zone,on the contrary,the fate of groundwater nitrate is strongly affected by groundwater level.Based on two sampling transects perpendicular to the riverbank,we found that the high level of nitrate corresponds to the deeper water table (25 m) near the urban center,where groundwater is heavily extracted.Groundwater nitrate is much lower (<12.4 mg/L) at localities with a shallow water table (5 m),which is likely caused by denitrification in the aquifer.

  7. Holter监测对小儿心律失常的诊断价值

    Institute of Scientific and Technical Information of China (English)

    廉婕; 王卫国; 吴鸿雁

    2010-01-01

    目的:观察动态心电监护监测(Holter监测)在临床诊断小儿心律失常中的应用价值。方法:选取我院自2008年1月~2009年12月收治的心率失常患儿106例进行心电图与Holter监测对比,比较两者的诊断率。结果:EKG监测异常者39例,无异常者67例,阳性率为36.8%;Holter监测异常者92例,无异常者14例,阳性率为86.8%。两组比较差异显著(P〈0.01)。结论:Holter监测能更准确、敏感的反映小儿心律失常的情况,值得临床推广使用。

  8. Holter监测对小儿心律失常的诊断价值

    Institute of Scientific and Technical Information of China (English)

    廉婕; 王卫国; 吴鸿雁

    2010-01-01

    目的:观察动态心电监护监测(Holter监测)在临床诊断小儿心律失常中的应用价值.方法:选取我院自2008年1月~2009年12月收治的心率失常患儿106例进行心电图与Holter监测对比,比较两者的诊断率.结果:EKG监测异常者39例,无异常者67例,阳性率为36.8%;Holter监测异常者92例,无异常者14例,阳性率为86.8%.两组比较差异显著(P<0.01).结论:Holter监测能更准确、敏感的反映小儿心律失常的情况,值得临床推广使用.

  9. Polymorphisms of the maternal Slug gene in fetal neural tube defects in a Chinese population

    Institute of Scientific and Technical Information of China (English)

    Li Guo; Hong Zhao; Yuheng Pei; Quanren He; Wan-I Li; Ting Zhang; Xiaoying Zheng; Ran Zhou; Jun Xie

    2010-01-01

    Several studies have demonstrated that Slug,which encodes a zinc finger of the Snail family of transcription factors,is a potential risk factor for neural tube defects.Neural tube defects tend to occur with a high rate in Shanxi province,China.The present case-control study investigated genotypic distributions and allele frequencies of Slug C1548A polymorphisms in DNA samples from59 women with a history of neural tube defect pregnancies and 73 controls during the same period from Shanxi Province,China.Results demonstrated that women with a history of neural tube defect pregnancies had significantly greater genotypic distributions of Slug AA genotypes and A allele frequencies compared with controls,and A allele Slug C1548A was a risk factor for neural tube defects(odds ratio = 3.444;95% confidence interval;2.021-5.868,P < 0.05).Three-dimensional structure prediction revealed that Slug C1548A resulted in transition of aspartic acid into glutamate at position 119.This indicated that these mutations could lead to damaged protein structure and function.These findings suggest that Slug C1548A gene polymorphism is closely related to neural tube defects in a population of Han Chinese origin from Shanxi Province,China

  10. Percutaneous expandable metallic stent biliary endoprostheses used inmalignant and benign obstructive jaundice

    Institute of Scientific and Technical Information of China (English)

    Hai Ying Liu; Wei Hua Tong; Wei Min Hu; Huai Ren Li; Zhe Sheng Wen; Jia Kang Wang; Wan Xi Huang; Shu Liu

    2000-01-01

    AIM To evaluate the effects of expandable metallic stent biliary endoprostheses (EMSBE) viaultrasonographic guided percutaneous transhepatic approach on the treatment of benign and malignantobstructive jaundice.METHODS Thirty-eight patients with obstructive jaundice (29 males and 9 females) aged 27 to 69 years(mean 54.7 years) were studied. Of them, 4 were benign and 34 malignant obstructions. Percutaneoustranshepatic cholangiography (PTC) was performed under ultrasonic guidance. A catheter was introducedinto the dilated bile duct via the introducer. A guide wire was inserted through the occlusive part of biliary duct after dilating with a double-lumen balloon catheter. A self-expandable metallic stent was inserted intcthe occlusive bile duct under fluoroscopic control.RESULTS The success rate of sonographic guided PTC was 100% (38/38) and the success rate of stentimplantation was 86.8% (33/ 38). Biliary obstruction was eliminated immediately, jaundice subsidedgradually and symptoms relieved after the procedure. During the 3 to 28 months fellow-up, re-occlusionoccurred in 4 malignant cases which were corrected by balloon catheter dilation and/or by stent, one patienthad secondary cholangitis and fifteen died without jaundice 6 - 28 months after the procedure. The otherswere alive with no jaundice. No severe complications or side effects were observed.CONCLUSION EMSBE via sonographic guided percutaneous transhepatic approach is a reliable and safepalliative therapy for malignant jaundice and an ideal nonoperative method for benign biliary obstruction. Ithas a definite positive impact on the quality of patient life.

  11. Preparation and evaluation of nattokinase-loaded self-double-emulsifying drug delivery system

    Directory of Open Access Journals (Sweden)

    Xiaona Wang

    2015-10-01

    Full Text Available In the present study, we prepared nattokinase-loaded self-double-emulsifying drug delivery system (SDEDDS and investigated its preliminary pharmacodynamics. The type and concentration of oil phase, inner aqueous phase and emulsifier were screened to prepare optimum nattokinase-loaded SDEDDS. Next, the optimum formulations were characterized based on microstructure, volume-weighted mean droplet size, self-emulsifying rate, yield, storage stability, in vitro release and in vivo pharmacodynamics studies. The water/oil/water multiple emulsions exhibited typical multiple structure, with relatively small volume-weighted mean droplet size 6.0 ± 0.7 μm and high self-emulsifying ability (self-emulsifying time <2 min. Encapsulation of nattokinase was up to 86.8 ± 8.2%. The cumulative release of nattokinase within 8 h was about 30%, exhibiting a sustained release effect. The pharmacodynamics study indicated that nattokinase-loaded SDEDDS could significantly prolong the whole blood clotting time in mouse and effectively improve the carrageenan-induced tail thrombosis compared with nattokinase solution. Moreover, we showed that SDEDDS could successfully self-emulsify into water/oil/water multiple emulsions upon dilution in dispersion medium with gentle stirring and effectively protect nattokinase activity in gastric environment. Our findings suggested that SDEDDS could be a promising strategy for peptide and protein drugs by oral administration.

  12. A long-term follow-up of the correlation between obstructive sleep apnea hypopnea syndrome and multiple organ diseases%老年人阻塞性睡眠呼吸暂停低通气综合征与多器官疾病关系的长期随访

    Institute of Scientific and Technical Information of China (English)

    曹永生; 戴煌; 倪竟全; 朱爱华; 王预建; 慈书平

    2014-01-01

    Objective To explore the correlation between obstructive sleep apnea hypopnea syndrome(OSAHS) and multiple organ diseases.Methods Home-visit questionnaires were performed in 1 868 subjects (956 male,912 female) with an average age of (79 ±5) years,and a prospective follow-up was performed for a period of 20 years with annual medical examinations.Multiple organ diseases included hypertension,coronary heart disease,stroke,diabetes,pulmonary heart disease,renal insufficiency and erythrocytosis.The subjects were grouped by the diagnosis of OSAHS.Results Among the 1 868 subjects,598 (32.0%) were diagnosed with OSAHS,and 1 270 (68.0%) of non-OSAHS as the control group.By the end of follow-up,in the OSAHS group there were 477(79.8%) cases with hypertension,337(56.4%) cases with coronary heart disease,167 (27.9%) cases with stroke,76 (12.7%) cases with diabetes,37 (6.2%) cases with pulmonary heart disease,73 (12.2%) cases with renal insufficiency and 211 (35.3%) cases with erythrocytosis,all of which were significantly higher than those of the control group [323 (25.4%),315(24.8%),95(7.5%),69(5.4%),40(3.2%),58(4.6%),30(2.4%),P<0.01].The number of diseases in the OSAHS group was also higher than that in the control group (P < 0.05).Conclusion The incidence of multiple organ diseases was remarkably higher in the OSAHS group than that in the control group,which indicated that OSAHS was a risk factor for multiple organ diseases.These diseases in OSAHS patients may be related to hypoxia caused by OSAHS,endocrine and metabolic disorders,unhealthy lifestyles and arteriosclerosis.%目的 随访观察老年人中OSAHS与多器官疾病的关系.方法 前瞻性纳入1989年11月至2009年11月13所军队和地方离退休干部休养所定期体检的老年人共1 868例,其中男956例,女912例,平均年龄(79±5)岁.多器官疾病主要包括:高血压、冠心病、脑卒中、糖尿病、肺源性心脏病、肾功能不全和红细胞增

  13. Ultratrace determination of arsenic in water samples by electrothermal atomic absorption spectrometry after pre-concentration with Mg-Al-Fe ternary layered double hydroxide nano-sorbent.

    Science.gov (United States)

    Abdolmohammad-Zadeh, Hossein; Jouyban, Abolghasem; Amini, Roghayeh

    2013-11-15

    A selective solid phase extraction method, based on nano-structured Mg-Al-Fe(NO3(-)) ternary layered double hydroxide as a sorbent, is developed for the pre-concentration of ultra-trace levels of arsenic (As) prior to determination by electrothermal atomic absorption spectrometry. It is found that both As(III) and As(V) could be quantitatively retained on the sorbent within a wide pH range of 4-12. Accordingly, the presented method is applied to determination of total inorganic As in aqueous solutions. Maximum analytical signal of As is achieved when the pyrolysis and atomization temperatures are close to 900 °C and 2300 °C, respectively. Several variables affecting the extraction efficiency including pH, sample flow rate, amount of nano-sorbent, elution conditions and sample volume are optimized. Under the optimized conditions, the limit of detection (3Sb/m) and the relative standard deviation are 4.6 pg mL(-1) and 3.9%, respectively. The calibration graph is linear in the range of 15.0-650 pg mL(-1) with a correlation coefficient of 0.9979, sorption capacity and pre-concentration factor are 8.68 mg g(-1) and 300, respectively. The developed method is validated by the analysis of a standard reference material (SRM 1643e) and is successfully applied to the determination of ultra-trace amounts of As in different water samples.

  14. Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure

    Science.gov (United States)

    Mathews, David H.; Disney, Matthew D.; Childs, Jessica L.; Schroeder, Susan J.; Zuker, Michael; Turner, Douglas H.

    2004-01-01

    A dynamic programming algorithm for prediction of RNA secondary structure has been revised to accommodate folding constraints determined by chemical modification and to include free energy increments for coaxial stacking of helices when they are either adjacent or separated by a single mismatch. Furthermore, free energy parameters are revised to account for recent experimental results for terminal mismatches and hairpin, bulge, internal, and multibranch loops. To demonstrate the applicability of this method, in vivo modification was performed on 5S rRNA in both Escherichia coli and Candida albicans with 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluene sulfonate, dimethyl sulfate, and kethoxal. The percentage of known base pairs in the predicted structure increased from 26.3% to 86.8% for the E. coli sequence by using modification constraints. For C. albicans, the accuracy remained 87.5% both with and without modification data. On average, for these sequences and a set of 14 sequences with known secondary structure and chemical modification data taken from the literature, accuracy improves from 67% to 76%. This enhancement primarily reflects improvement for three sequences that are predicted with <40% accuracy on the basis of energetics alone. For these sequences, inclusion of chemical modification constraints improves the average accuracy from 28% to 78%. For the 11 sequences with <6% pseudoknotted base pairs, structures predicted with constraints from chemical modification contain on average 84% of known canonical base pairs. PMID:15123812

  15. Examining Urban Impervious Surface Distribution and Its Dynamic Change in Hangzhou Metropolis

    Directory of Open Access Journals (Sweden)

    Longwei Li

    2016-03-01

    Full Text Available Analysis of urban distribution and its expansion using remote sensing data has received increasing attention in the past three decades, but little research has examined spatial patterns of urban distribution and expansion with buffer zones in different directions. This research selected Hangzhou metropolis as a case study to analyze spatial patterns and dynamic changes based on time-series urban impervious surface area (ISA datasets. ISA was developed from Landsat imagery between 1991 and 2014 using a hybrid approach consisting of linear spectral mixture analysis, decision tree classifiers, and post-processing. The spatial patterns of ISA distribution and its dynamic changes in eight directions—east, southeast, south, southwest, west, northwest, north, and northeast—at the temporal scale were analyzed with a buffer zone-based approach. This research indicated that ISA can be extracted from Landsat imagery with both producer and user accuracies of over 90%. ISA in Hangzhou metropolis increased from 146 km2 in 1991 to 868 km2 in 2014. Annual ISA growth rates were between 15.6 km2 and 48.8 km2 with the lowest growth rate in 1994–2000 and the highest growth rate in 2005–2010. Urban ISA increase before 2000 was mainly due to infilling within the urban landscape, and, after 2005, due to urban expansion in the urban-rural interfaces. Urban expansion in this study area has different characteristics in various directions that are influenced by topographic factors and urban development policies.

  16. Chemical Composition and Antioxidant Activity of Essential Oils from Cinnamodendron dinisii Schwacke and Siparuna guianensis Aublet

    Directory of Open Access Journals (Sweden)

    Milene Aparecida Andrade

    2013-11-01

    Full Text Available The objectives of this study were to chemically characterize and evaluate the antioxidant activity of essential oils Cinnamodendron dinisii Schwacke (pepper and Siparuna guianensis Aublet (negramina. The essential oil was isolated by hydrodistillation using a Clevenger modified apparatus, and the identification and quantification of constituents, through GC/MS and GC-FID analysis. The antioxidant activity was evaluated using β-carotene/linoleic acid system and the DPPH radical sequestering method. In chromatographic analysis, the majority constituents found in the essential oil of C. dinisii were bicyclic monoterpenes, α-pinene (35.41%, β-pinene (17.81%, sabinene (12.01% and sesquiterpene bicyclogermacrene (7.59%. In the essential oil of the fresh leaves of Siparuna guianensis Aublet, acyclic monoterpene, β-myrcene (13.14%, and sesquiterpenes, germacrene-D (8.68% and bicyclogermacrene (16.71% were identified. The antioxidant activity was low by the β-carotene/linoleic acid test and was not evidenced by the DPPH test, for both oils evaluated.

  17. FCRD Milestone Report: M21AF050901

    Energy Technology Data Exchange (ETDEWEB)

    Hoelzer, David T [ORNL; Sokolov, Mikhail A [ORNL; Byun, Thak Sang [ORNL; Odette, George R. [University of California, Santa Barbara; Klingensmith, Doug [University of California, Santa Barbara; Gragg, David [University of California, Santa Barbara; Stergar, Eric [University of California, Santa Barbara; Fields, Kirk [University of California, Santa Barbara

    2011-09-01

    The objective of this study was to perform mechanical testing on large scale heats of the advanced ODS 14YWT alloy to investigate the effects of processing parameters on mechanical properties. Mechanical properties tests were conducted on two heats of the advanced ODS 14YWT ferritic alloy: the 14YWT-SM11 was produced by extrusion at ORNL and OW4 was produced by HIP at UCSB. The 14YWT-SM11 showed very high tensile strength compared to OW4, but showed less ductility as a result. The fracture toughness transition temperature of 14YWT-SM11 was determined in two orientations and showed T{sub 0} = 48 C in the favorably strong L-T direction while shifting by 63 C to T{sub 0} = 111 C in the weaker T-L direction. The fracture toughness transition temperature for OW4 was not determined but appeared to be within the range observed for 14YWT-SM11. The fracture toughness of 14YWT-SM11 at room temperature was 86.8 MPa{radical}m and 93.1 MPa{radical}m, which was much higher than that of OW4 (27.4 MPa{radical}m). The strain rate jump tests conducted on OW4 indicated that the creep properties were similar to MA957 at 750 C.

  18. 7种杀虫剂对油菜病毒病和传毒媒介蚜虫的防效评价%Control Efficiency Evaluation of Seven Insecticides against Oilseed Rape Virus Diseases and Its Viruliferous Aphids

    Institute of Scientific and Technical Information of China (English)

    赵敏; 张国忠; 李荣; 吴传伟; 洪美萍; 徐福寿

    2010-01-01

    田间防效试验结果表明:25%吡蚜酮WP 90 g a.i./hm2、25%噻虫嗪WG 18.75 g a.i./hm2、15%吡·丁硫EC33.75 g a.i./hm2、70%吡虫啉WG 31.5 g a.i./hm2、10%吡虫啉WP 30 g a.i./hm2对油菜蚜虫和油菜病毒病均有较好的防效,其中25%噻虫嗪WG、15%吡·丁硫EC、70%吡虫啉WG、10%吡虫啉WP处理后3~5 d对蚜虫的防效高达72.1%~83.6%,25%吡蚜酮WP处理后10 d的防效高达79%,而对病毒病的防效为86.8%~94.3%.18%吡·噻WP81 g a.i./hm2、5%啶虫脒WP 18.75 g a.i./hm2对蚜虫的防效差,药后3~7 d的防效分别为46%~73%和47%~65%.

  19. La excesiva onerosidad sobrevenida en la contratación mercantil: una aproximación desde la perspectiva de la jurisdicción civil en Colombia

    Directory of Open Access Journals (Sweden)

    Javier Andrés Franco Zárate

    2012-12-01

    Full Text Available La vigencia del principio pacta sunt servanda implica para las partes la obligatoriedad de respetar lo acordado inicialmente en los negocios jurídicos que celebran en ejercicio de la autonomía de la voluntad. Sin embargo, con ocasión de los importantes y en veces repentinos cambios económicos, se abre paso la discusión de si las partes deben estar en todo caso atadas al cumplimiento de contratos en los que la prestación a cargo se ha tornado sin su culpa y luego de su celebración excesivamente onerosa. Así, se ha abierto paso la posibilidad de revisión del contrato en aplicación de la llamada “teoría de la imprevisión” bajo ciertas circunstancias. El artículo desarrolla un examen de la evolución y requisitos de la figura en la jurisprudencia civil y comercial colombiana, a la vez que analiza los poderes del juez civil en el marco del artículo 868 C.Co. colombiano para revisar y modificar el contrato.

  20. Laboratory Study on the Potential EOR Use of HPAM/VES Hybrid in High-Temperature and High-Salinity Oil Reservoirs

    Directory of Open Access Journals (Sweden)

    Dingwei Zhu

    2013-01-01

    Full Text Available Polymer flooding represents one of the most efficient processes to enhance oil recovery, and partially hydrolyzed polyacrylamide (HPAM is a widely used oil-displacement agent, but its poor thermal stability, salt tolerance, and mechanical degradation impeded its use in high-temperature and high-salinity oil reservoirs. In this work, a novel viscoelastic surfactant, erucyl dimethyl amidobetaine (EDAB, with improved thermal stability and salinity tolerance, was complexed with HPAM to overcome the deficiencies of HPAM. The HPAM/EDAB hybrid samples were studied in comparison with HPAM and EDAB in synthetic brine regarding their rheological behaviors and core flooding experiments under simulated high-temperature and high-salinity oil reservoir conditions (T: 85°C; total dissolved solids: 32,868 mg/L; [Ca2+] + [Mg2+]: 873 mg/L. It was found that the HPAM/EDAB hybrids exhibited much better heat- and salinity-tolerance and long-term thermal stability than HPAM. Core flooding tests showed that the oil recovery factors of HPAM/EDAB hybrids are between those of HPAM and EDAB. These results are attributed to the synergistic effect between HPAM and EDAB in the hybrid.

  1. Developing synergy regression models with space-borne ALOS PALSAR and Landsat TM sensors for retrieving tropical forest biomass

    Indian Academy of Sciences (India)

    Suman Sinha; C Jeganathan; L K L K Sharma; M S Nathawat; Anup K Das; Shiv Mohan

    2016-06-01

    Forest stand biomass serves as an effective indicator for monitoring REDD (reducing emissions fromdeforestation and forest degradation). Optical remote sensing data have been widely used to derive forestbiophysical parameters inspite of their poor sensitivity towards the forest properties. Microwave remotesensing provides a better alternative owing to its inherent ability to penetrate the forest vegetation.This study aims at developing optimal regression models for retrieving forest above-ground bole biomass(AGBB) utilising optical data from Landsat TM and microwave data from L-band of ALOS PALSARdata over Indian subcontinental tropical deciduous mixed forests located in Munger (Bihar, India). Spatialbiomass models were developed. The results using Landsat TM showed poor correlation (R^2 =0.295and RMSE=35 t/ha) when compared to HH polarized L-band SAR (R^2 =0.868 and RMSE=16.06 t/ha).However, the prediction model performed even better when both the optical and SAR were used simultaneously(R^2 =0.892 and RMSE=14.08 t/ha). The addition of TM metrics has positively contributed inimproving PALSAR estimates of forest biomass. Hence, the study recommends the combined use of bothoptical and SAR sensors for better assessment of stand biomass with significant contribution towardsoperational forestry.

  2. Mathematical and statistical analysis of the effect of boron on yield parameters of wheat

    Energy Technology Data Exchange (ETDEWEB)

    Rawashdeh, Hamzeh [Water Management and Environment Research Department, National Center for Agricultural Research and Extension, P.O. Box 639, Baqa 19381 (Jordan); Sala, Florin [Soil Science and Plant Nutrition, Faculty of Agriculture, Banat University of Agricultural Sciences and Veterinary Medicine “Regele Mihai I al României” from Timişoara, Timişoara, 300645 (Romania); Boldea, Marius [Mathematics and Statistics, Faculty of Agriculture, Banat University of Agricultural Sciences and Veterinary Medicine “Regele Mihai I al României” from Timisoara, Timişoara, 300645 (Romania)

    2015-03-10

    The main objective of this research is to investigate the effect of foliar applications of boron at different growth stages on yield and yield parameters of wheat. The contribution of boron in achieving yield parameters is described by second degree polynomial equations, with high statistical confidence (p<0.01; F theoretical < F calculated, according to ANOVA test, for Alfa = 0.05). Regression analysis, based on R{sup 2} values obtained, made it possible to evaluate the particular contribution of boron to the realization of yield parameters. This was lower for spike length (R{sup 2} = 0.812), thousand seeds weight (R{sup 2} = 0.850) and higher in the case of the number of spikelets (R{sup 2} = 0.936) and the number of seeds on a spike (R{sup 2} = 0.960). These results confirm that boron plays an important part in achieving the number of seeds on a spike in the case of wheat, as the contribution of this element to the process of flower fertilization is well-known. In regards to productivity elements, the contribution of macroelements to yield quantity is clear, the contribution of B alone being R{sup 2} = 0.868.

  3. Neuro-fuzzy modeling to predict physicochemical and microbiological parameters of partially dried cherry tomato during storage: effects on water activity, temperature and storage time.

    Science.gov (United States)

    Tao, Yang; Li, Yong; Zhou, Ruiyun; Chu, Dinh-Toi; Su, Lijuan; Han, Yongbin; Zhou, Jianzhong

    2016-10-01

    In the study, osmotically dehydrated cherry tomatoes were partially dried to water activity between 0.746 and 0.868, vacuum-packed and stored at 4-30 °C for 60 days. Adaptive neuro-fuzzy inference system (ANFIS) was utilized to predict the physicochemical and microbiological parameters of these partially dried cherry tomatoes during storage. Satisfactory accuracies were obtained when ANFIS was used to predict the lycopene and total phenolic contents, color and microbial contamination. The coefficients of determination for all the ANFIS models were higher than 0.86 and showed better performance for prediction compared with models developed by response surface methodology. Through ANFIS modeling, the effects of storage conditions on the properties of partially dried cherry tomatoes were visualized. Generally, contents of lycopene and total phenolics decreased with the increase in water activity, temperature and storage time, while aerobic plate count and number of yeasts and molds increased at high water activities and temperatures. Overall, ANFIS approach can be used as an effective tool to study the quality decrease and microbial pollution of partially dried cherry tomatoes during storage, as well as identify the suitable preservation conditions.

  4. Interest in genetic testing in Ashkenazi Jewish Parkinson's disease patients and their unaffected relatives.

    Science.gov (United States)

    Gupte, Manisha; Alcalay, Roy N; Mejia-Santana, Helen; Raymond, Deborah; Saunders-Pullman, Rachel; Roos, Ernest; Orbe-Reily, Martha; Tang, Ming-X; Mirelman, Anat; Ozelius, Laurie; Orr-Urtreger, Avi; Clark, Lorraine; Giladi, Nir; Bressman, Susan; Marder, Karen

    2015-04-01

    Our objective was to explore interest in genetic testing among Ashkenazi Jewish (AJ) Parkinson's Disease (PD) cases and first-degree relatives, as genetic testing for LRRK2 G2019S is widely available. Approximately 18 % of AJ PD cases carry G2019S mutations; penetrance estimations vary between 24 and 100 % by age 80. A Genetic Attitude Questionnaire (GAQ) was administered at two New York sites to PD families unaware of LRRK2 G2019S mutation status. The association of G2019S, age, education, gender and family history of PD with desire for genetic testing (outcome) was modeled using logistic regression. One-hundred eleven PD cases and 77 relatives completed the GAQ. Both PD cases and relatives had excellent PD-specific genetic knowledge. Among PD, 32.6 % "definitely" and 41.1 % "probably" wanted testing, if offered "now." Among relatives, 23.6 % "definitely" and 36.1 % "probably" wanted testing "now." Desire for testing in relatives increased incrementally based on hypothetical risk of PD. The most important reasons for testing in probands and relatives were: if it influenced medication response, identifying no mutation, and early prevention and treatment. In logistic regression, older age was associated with less desire for testing in probands OR = 0.921 95%CI 0.868-0.977, p = 0.009. Both probands and relatives express interest in genetic testing, despite no link to current treatment or prevention.

  5. Quality of life in patients with hand eczema as health promotion: a case control study.

    Science.gov (United States)

    Ghaderi, Reza; Saadatjoo, Alireza

    2014-01-01

    Health promotion has been defined by the World Health Organization's (WHO) 2005 Bangkok Charter for Health Promotion as "the process of enabling people to increase control over their health and its determinants, and thereby improve their health". One of the most important determinants of health is quality of life. Hand eczema is a common skin disease that can adversely affect the quality of life of patients. The aim of this study was to determine the quality of life in patients with hand eczema. This case-control study was performed on 70 patients with hand eczema and 70 healthy controls. All the patients filled out two questionnaires: Short Form 36 (SF-36) and Dermatology Life Quality index (DLQI). The data were analyzed using the statistical software package for social sciences (SPSS). The mean score score of quality of life in dimensions of physical functioning, vitality, and general health in the SF-36 was lower compared to the control group. The mean score in DLQI in patients with hand eczema was 8.68. There was a significant negative correlation between the scores of different dimensions of QOL obtained in the two questionnaires (SF36 and DLQI). The study demonstrated that the quality of life in patients with hand eczema was lower than that of controls. It seems advisable that psychiatric consultations or psychotherapy be included in the treatment of chronic hand eczema.

  6. Growth and fabrication method of CdTe and its performance as a radiation detector

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Hyojeong [Korea Atomic Energy Research Institute, Jeong-eup (Korea, Republic of); Sungkyunkwan University, Suwon (Korea, Republic of); Jeong, Manhee; Kim, Hansoo; Kim, Youngsoo; Ha, Jangho [Korea Atomic Energy Research Institute, Jeong-eup (Korea, Republic of); Chai, Jong-Seo [Sungkyunkwan University, Suwon (Korea, Republic of)

    2015-01-15

    A CdTe crystal ingot doped with 2000 ppm of Cl was grown by using the low-pressure Bridgman (LPB) method at the Korea Atomic Energy Research Institute (KAERI). A Semiconductor detector as a radiation detection sensor with a size of 7 (W) x 6.5 (D) x 2 (H) mm{sup 3} was fabricated from the CdTe ingot. In addition, the properties of the CdTe sample were observed through four kinds of experiments to analyze its performance. The resistivity was obtained as 1.41 x 10{sup 10} Ωcm by using a Keithley 6517A high-precision electrometer. The mobility-life time products for electrons and holes were 3.137 x 10{sup -}'4 cm{sup 2}/V and 4.868 x 10{sup -5} cm{sup 2}/V, respectively. Finally, we achieved a 16.8% energy resolution at 59.5 keV for the {sup 241}Am gamma-ray source. The CdTe semiconductor detector grown at KAERI has a performance good enough to detect low-energy gamma-rays.

  7. Saudi Moumouvirus, the first group B mimivirus isolated from Asia

    Directory of Open Access Journals (Sweden)

    Leena Hussein Bajrai

    2016-12-01

    Full Text Available The number of novel giant viruses identified and characterized from the recently proposed order Megavirales has increased in recent years and new questions have been raised regarding viral diversity and evolution. Here, we describe the isolation and characterization of Saudi moumouvirus (SDMV, a new giant virus belonging to Mimivirus lineage B, isolated from a sewage sample taken from the King Abdulaziz University hospital in Jeddah, Saudi Arabia. SDMV presented 500 nm icosahedral particles with a 1,046,087 bp genome, which is larger than moumouvirus-like genomes which have been described in the past. The SDMV genome was predicted to encode 868 ORFs, ranging in size from 54 to 2,914 amino acids, with a mean size of 349 aa. Furthermore, this genome was predicted to encode 40 new genes (ORFans without similarity with other sequences (ORFan L850 transcript was detected by qPCR in infected amoeba, in addition to 42 hypothetical proteins (pseudo-ORFs with less than 100 aa, which matched other sequences in the NCBI nr database. Phylogenetic analysis showed that SDMV clustered together with mimiviruses from lineage B, including moumouvirus-like strains. It is, therefore, the 3rd Mimivirus to be isolated in Asia and the first of group B.

  8. ANA、抗ds-DNA、抗ENA多肽抗体谱联合检测对SLE的临床诊断价值%Clinical diagnostic value of collective determination of ANA,anti-ds-DNA,anti-EN A polypeptide antibody spectrum for SLE

    Institute of Scientific and Technical Information of China (English)

    李义德; 张玉蓉; 王刚; 王利新

    2001-01-01

    目的探讨ANA、抗ds-DNA、抗ENA多肽抗体谱联合检测在诊断SLE病人中的应用.方法ANA、抗ds-DNA采用间接免疫荧光法;ENA多肽抗体采用免疫印迹法(IBT).结果检测167例SLE患者,ANA阳性率为86.8%;抗ds-DNA阳性率为67.1%;抗ENA多肽抗体阳性率为71.9%,其中18例ANA为阴性而抗ENA多肽抗体为阳性.结论 AN A、抗ds-DNA、抗ENA多肽抗体谱联合检测在SLE诊断中具有互补性,并能提高检出率.对SLE 的诊断分型、治疗预后均有重要的临床价值.

  9. Hydrothermal synthesis of a new organic-inorganic hybrid with Dawson type polyanions as building blocks: Na3(C7NH8O2)3[P2W18O62]·16H2O

    Science.gov (United States)

    Hmida, Fatma; Ayed, Brahim; Haddad, Amor

    2016-07-01

    A new organic-inorganic hybrid compound based on dawson polyoxotungstate, Na3(C7NH8O2)3 [P2W18O62].16H2O have been isolated under autogenous pressure method and characterized by single-crystal X-ray diffraction, infrared, ultraviolet spectroscopy, cyclic voltammetry and Thermogravimetric analysis (TGA). This compound crystallized in the triclinic system, space group P-1, with a = 14.063 (1) Å; b = 17.009 (1) Å; c = 17.868 (1) Å; α = 79.88 (1)°; β = 77.14 (1)°; γ = 79.25 (1)° and Z = 2. The crystal structures of the compounds exhibit three-dimensional supramolecular assembly based on the extensive hydrogen bonding interactions between organic cations, sodium cations, water molecules and Dawson polyoxoanions. The infrared spectrum fully confirms the X-ray crystal structure and the UV spectrum of the title compound exhibits an absorption peak at 295 nm.

  10. Life History of the Tamarind Weevil, Sitophilus linearis (Herbst (Coleoptera: Curculionidae, on Tamarind Seed

    Directory of Open Access Journals (Sweden)

    James Adebayo Ojo

    2015-01-01

    Full Text Available The tamarind weevil, Sitophilus linearis Herbst (Coleoptera: Curculionidae, is an important pest of tamarind and other Caesalpinioideae. Investigating its life history is important in the implementation of management strategy. Its life history was monitored daily to understand its developmental biology on tamarind seed following standard procedures under laboratory conditions of 24–30°C temperature, 60–70% relative humidity, and 12L : 12D photoperiod. The egg incubation period lasted 3.17 ± 0.07 days. A mated female of S. linearis laid an average of 165 ± 5.78 eggs during an oviposition period of 86.8 ± 2.47 days. There were four larval instars, with a total larval developmental period of 16 days. The pupal period lasted 8 days, and adult lived 108.5 ± 3.61 days. The overall growth ratio for the four instars was 1.33. There was a regular relationship and significant correlation (r=0.94 between the stages of larval development and head capsule width.

  11. LAS COMPETENCIAS DEL PROFESORADO EN TIC: ESTRUCTURA BÁSICA

    Directory of Open Access Journals (Sweden)

    Jesús M. Suárez Rodríguez

    2013-01-01

    Full Text Available Las competencias en TIC del profesorado son una variable clave para la integración de las TIC en la escuela. Este artículo presenta un esquema de indicadores de competencia para dos dimensiones, competencias tecnológicas y competencias pedagógicas, desde un modelo MIMIC. El modelo incluye la definición de una relación específica entre estas dimensiones y también de los efectos de un conjunto de factores relevantes: personales (género, edad y frecuencia de uso del ordenador y contextuales (tipo de centro, etapa educativa y acceso al aula de informática. La información se recogió mediante un cuestionario aplicado a una muestra de 868 profesoras y profesores de educación primaria y secundaria de la Comunidad Valenciana. Los resultados confirman la estructura relacional estable entre ambas dimensiones de competencia, así como que las competencias tecnológicas influyen sobre las pedagógicas. Asimismo, el modelo muestra las influencias de los factores personales y contextuales sobre estas dimensiones. El modelo presentado apunta la necesidad urgente de estudiar las dimensiones relacionadas con las TIC en educación desde una perspectiva más compleja que pueda mostrar más claramente esas relaciones.

  12. Cardiovascular risk factors and estimated 10-year risk of fatal cardiovascular events using various equations in Greeks with metabolic syndrome.

    Science.gov (United States)

    Chimonas, Theodoros; Athyros, Vassilios G; Ganotakis, Emmanouel; Nicolaou, Vassilios; Panagiotakos, Demosthenes B; Mikhailidis, Dimitri P; Elisaf, Moses

    2010-01-01

    We investigated cardiovascular disease (CVD) risk factors in 1501 Greeks (613 men and 888 women, aged 40-65 years) referred to outpatients with metabolic syndrome (MetS) and without diabetes mellitus or CVD. The 10-year risk of fatal CVD events was calculated using European Society of Cardiology Systematic Coronary Risk Estimation (ESC SCORE), Hellenic-SCORE, and Framingham equations. Raised blood pressure (BP) and hypertriglyceridemia were more common in men (89.6% vs 84.2% and 86.8% vs 74.2%, respectively; P < .001). Low high-density lipoprotein cholesterol (HDL-C) and abdominal obesity were more common in women (58.2% vs 66.2% and 85.8% vs 97.1%, respectively; P < .001). The 10-year risk of fatal CVD events using HellenicSCORE was higher in men (6.3% +/- 4.3% vs 2.7% +/- 2.1%; P < .001). European Society of Cardiology Systematic Coronary Risk Estimation and Framingham yielded similar results. The risk equations gave similar assessments in a European Mediterranean population except for HellenicSCORE that calculated more MetS women requiring risk modification. This might justify local risk engine evaluation in event-based studies. (Clinical-Trials.gov ID: NCT00416741).

  13. Effect of Heat Treatment on Microstructures and Mechanical Properties of Severe Plastically Deformed Hypo- and Hyper-Eutectoid Steels by Caliber Rolling Process.

    Science.gov (United States)

    Yun, Shin-Cheon; Kim, Hyun-Jin; Bae, Chul-Min; Lee, Kee-Ahn

    2016-02-01

    This study investigated the effect of post-heat treatment on the microstructures and mechanical properties of severe plastically deformed hypo- and hyper-eutectoid steels that underwent a caliber rolling process. First, 28 passes of caliber rolling were performed on both the hypo-eutectoid steel with Fe-0.47% C (wt%) composition and the hyper-eutectoid steel with Fe-1.02%C (wt%) composition. Then, the caliber rolled materials underwent heat treatment at 500 degrees C for 1, 3, 5, 10, 30 and 60 minutes. The caliber rolled steel possessed a 300-400 nm-sized oval cementite structure created through elongating and segmentation regardless of the C composition. The observation of heat-treated microstructures showed that cementite structure became globular and ferrite size increased as heat treatment temperature increased. In the hardness measurement, the initial caliber rolled samples showed 372.8 Hv (hypoeutectoid) and 480.1 Hv (hyper-eutectoid). However, hardness dramatically decreased up to 10 min. heat treatments, and then showed a constant or small reduction with time. The yield strengths (compression) of caliber rolled hypo- and hypereutectoid steels obtained were 1097 MPa and 1426 MPa, respectively, and the yield strengths of the same steels after heat treatment (500 degrees C, 60 min.) were identified to be 868 MPa and 1316 MPa, respectively.

  14. Hydrothermal alteration at the Roosevelt Hot Springs thermal area, Utah: Petrographic characterization of the alteration to 2 kilometers depth

    Energy Technology Data Exchange (ETDEWEB)

    Ballantyne, J.M.; Parry, W.T.

    1978-04-01

    Hydrothermal alteration in drill cuttings from Thermal Power drillhole 14-2, Roosevelt Hot Springs Thermal area, has been studied petrographically. The hole is sited in alluvium approximately 1.6 km southeast of the old Resort and was rotary drilled to a depth of 1866.0 m. The exact hole location is 2310 FNL, 350 FWL, Sec. 2, Twp 27S, Rge 9W, elevation 1908.5 m. Core was extracted from 792.5 to 795.5 m. Thin sections were made from samples at 15.2 m intervals of drill cuttings collected at 1.5 or 3.0 m intervals during drilling. Thin sections were made of 1.5 or 3.0 m intervals from 274.3 to 304.8 m, 487.9 to 581.2 m, and 868.7 to 899.2 m. These intervals were chosen for close spaced sampling on the basis of increases in temperature, porosity, conductivity and acoustic velocity shown in geophysical logs. A total of 153 thin sections of cuttings were made, and an additional 9 sections were made from the core. Depths of thin section samples are listed in the appendix. A visual estimate of the percentage of each rock type was made for each thin section.

  15. Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their Immune-Endocrine Profile

    Directory of Open Access Journals (Sweden)

    Ariana Díaz

    2015-01-01

    Full Text Available Tuberculosis (TB is a major health problem requiring an appropriate cell immune response (IR to be controlled. Since regulatory T cells (Tregs are relevant in IR regulation, we analyzed Tregs variations throughout the course of TB treatment and its relationship with changes in immune-endocrine mediators dealing with disease immunopathology. The cohort was composed of 41 adult patients, 20 of them completing treatment and follow-up. Patients were bled at diagnosis (T0 and at 2 (T2, 4 (T4, 6 (T6, and 9 months following treatment initiation. Twenty-four age- and sex-matched healthy controls (HCo were also included. Tregs (flow cytometry from TB patients were increased at T0 (versus HCo P<0.05, showing even higher values at T2 (versus T0 P<0.01 and T4 (versus T0 P<0.001. While IL-6, IFN-γ, TGF-β (ELISA, and Cortisol (electrochemiluminescence, EQ were augmented, DHEA-S (EQ levels were diminished at T0 with respect to HCo, with cytokines and Cortisol returning to normal values at T9. Tregs correlated positively with IFN-γ (R=0.868, P<0.05 at T2 and negatively at T4 (R=-0.795, P<0.05. Lowered levels of proinflammatory cytokines together with an increased frequency of Tregs of patients undergoing specific treatment might reflect a downmodulatory effect of these cells on the accompanying inflammation.

  16. 靳三针配合智力训练治疗儿童精神发育迟滞疗效观察%Observations on the Efficacy of Jin’s Three-needle Acupuncture plus Intelligence Training in Treating Mental Retardation in Children

    Institute of Scientific and Technical Information of China (English)

    胡怡佳; 黄任秀; 覃中华; 谭丽金; 罗雪梅; 曾懿懿

    2015-01-01

    目的:观察靳三针配合智力训练治疗6岁以下儿童精神发育迟滞的临床疗效。方法将300例0~6岁精神发育迟滞患者根据家长意愿分为治疗组和对照组,每组150例。治疗组采用靳三针配合智力训练治疗,对照组采用单纯智力训练治疗。两组治疗前后均采用盖塞尔发育商量表中文修订版进行评估。结果治疗组总有效率为84.7%,对照组为73.3%,两组比较差异具有统计学意义(P<0.05)。治疗组肝肾亏虚型、心脾不足型、痰瘀互阻型及气虚血瘀型患者总有效率分别为86.8%、86.8%、76.5%和75.0%,对照组分别为76.2%、76.8%、62.5%和60.0%,两组不同中医分型总有效率比较,差异均具有统计学意义(P<0.05)。治疗组轻度、中度、重度及极重度患者总有效率分别为96.9%、94.7%、66.7%和44.4%,对照组分别为90.0%、82.5%、47.8%和35.3%。两组中度、重度及极重度患者总有效率比较,差异均具有统计学意义(P<0.05)。结论靳三针配合智力训练是一种治疗儿童精神发育迟滞的有效方法。%Objective To investigate the clinical efficacy of Jin’s three-needle acupuncture plus intelligence training in treating mental retardation in children under 6 years old. Methods Three hundred mental retardation patients aged 0 to 6 were randomly allocated, according to their parents’ willingness, to treatment and control groups, 150 cases each. The treatment group received Jin’s three-needle acupuncture plus intelligence training and the control group, intelligence training alone. An assessment was made using Chinese revised version of the Gesell Developmental Schedules in both groups before and after treatment.Results The total efficacy rate was 84.7% in the treatment group and 73.3% in the control group; there was a statistically significant difference between the two groups (P<0.05). The total efficacy rates in liver-kidney deficiency, heart-spleen deficiency

  17. E-learning vs. classroom instruction in infection control in a dental hygiene program.

    Science.gov (United States)

    Garland, Kandis V

    2010-06-01

    The purpose of this project was to evaluate e-learning versus classroom instruction in infection control by comparing outcomes of multiple-choice examination scores and clinical competency-based examinations (CBE) between two groups of first-year dental hygiene students (fall 2008 e-learning: n=26; fall 2009 classroom instruction: n=26). Contents of both instructional units were comparable and were developed by the Organization for Safety, Asepsis, and Prevention. All students in each group were required to complete infection control instruction as part of the preclinical curriculum (didactic and clinical) and were tested on the material using the multiple-choice examination and clinical CBE. Both groups' scores on the multiple-choice examination ranged from 74 percent to 94 percent (n=26 to 33 of 35), with e-learning mean score=82.8 percent, n=29 of 35, and classroom instruction mean score=86.8 percent, n=30 of 35. A two-tailed independent samples t-test indicated a statistically significant difference between the two groups on the multiple-choice examination (p=0.11). The Fisher's exact test indicated no statistically significant difference between the two groups on the first-time pass rate for the clinical CBE (p=0.668). Findings demonstrated little difference between the two methods for teaching infection control. Thus, either method may be chosen. Future research should examine a blended approach with larger samples and longitudinal data.

  18. VALORACIÓN Y COMPARACIÓN DE LA DISPOSICIÓN SAGITAL DEL RAQUIS ENTRE CANOÍSTAS Y KAYAKISTAS DE CATEGORÍA INFANTIL

    Directory of Open Access Journals (Sweden)

    Pedro Ángel López Miñarro

    2008-01-01

    dorsal en bipedestación fueron de 42,22º ± 7,76º para los kayakistas y de 37,45º ± 8,68º para los canoístas. En cuanto a la lordosis lumbar estos valores fueron de 27,91º ± 6,21º y 25,70º ± 6,15º, respectivamente. En el test dedos-planta, en las curvas dorsal y lumbar los resultados obtenidos fueron de 63,78º ± 6,21º y 33,70º ± 7,18º, respectivamente para kayakistas y de 65,35º ± 11,48º y 30,55º ± 6,33º para canoístas. No existieron diferencias significativas entre kayakistas y canoístas. En base a las referencias de normalidad, se encontró un alto porcentaje de morfotipos cifóticos, especialmente en la curva lumbar. En conclusión, existe una alta frecuencia de morfotipos alterados en flexión máxima del tronco y en sedentación asténica, especialmente en el raquis lumbar, aunque la disciplina practicada (kayak o canoa no genera diferencias significativas en la disposición sagital del raquis.

  19. Target radiofrequency combined with collagenase chemonucleolysis in the treatment of lumbar intervertebral disc herniation.

    Science.gov (United States)

    Zhang, Daying; Zhang, Yong; Wang, Zhijian; Zhang, Xuexue; Sheng, Mulan

    2015-01-01

    Both target radiofrequency thermocoagulation and collagenase chemonucleolysis are effective micro-invasive therapy means for lumbar intervertebral disc herniation. In order to analyze the clinical effects of target radiofrequency thermocoagulation combined with collagenase chemonucleolysis on lumbar intervertebral disc herniation, the contents of hydroxyproline and glycosaminoglycan were measured and the histological changes of nucleus pulposus was detected in the vitro experiments. Radiofrequency thermocoagulation reduced the hydrolyzation of herniated nucleus pulposus caused by collagenase, as well as the content of hydroxyproline and glycosaminoglycan. Furthermore, 236 patients with lumbar intervertebral disc herniation were treated by target radiofrequency thermocoagulation combined with collagenase chemonucleolysis. The efficiency was evaluated according to Macnab criteria, and the index of lumbar disc herniation (IDH) was compared pre-operation with 3 months post-operation. The post-operative good rate was 66.5% (157/236) at 2 weeks post-operation, and 88.1% (208/236) at 3 months post-operation. In the post-operative follow-up exam, 86.8% of the re-examined cases demonstrated smaller or ablated protrusion, with reduced IDH values from pre-operation, which was statistically significant. No serious complications were detected intra-operatively and post-operatively. In conclusion, target radiofrequency combined with collagenase chemonucleolysis was an effective and safe method for treatment of lumbar intervertebral disc herniation.

  20. Syntheses of Binuclear Copper(Ⅰ)Complexes Containing Benzimidazole

    Institute of Scientific and Technical Information of China (English)

    LIU Ying-Fan; ZHAO Dong; GUO Li-Bing; ZHENG Xin; SUN Yu-An

    2005-01-01

    A binuclear copper(Ⅰ) complex [Cu2(dppm)2(C7H6N2)2](NO3)2 (C7H6N2 = benzimidazole, dppm = Ph2PCH2PPh2) has been synthesized and characterized by X-ray crystallography.The crystal belongs to monoclinic, space group C2/c with a = 14.167(3), b = 21.209(4), c =20.680(4) A, β = 103.93(3)°, C32H28CuN3O3P2, Mr = 628.05, Z = 8,μ = 0.868 mm-1, V = 6031 (2)(。A)3,F(000) = 2592, Dc= 1.383 g/cm3, R = 0.0593 and wR = 0.1736.A total of 5297 independent reflec tions were collected, of which 3503 were observed with I > 2σ(I).The central copper atom is tri-coordinated by phosphorus atoms from bridging dppm and nitrogen atom from benzimidazole.In the coordination sphere, the bond lengths of Cu-P(1) and Cu-P(2) are 2.2607(17) and 2.2503(16)(。A),respectively and the P-Cu-P bond angle is 127.26(6)°.

  1. Antioxidant activity of three microalgae Dunaliella salina, Tetraselmis chuii and Isochrysis galbana clone Tahiti

    Science.gov (United States)

    Widowati, Ita; Zainuri, Muhammad; Pancasakti Kusumaningrum, Hermien; Susilowati, Ragil; Hardivillier, Yann; Leignel, Vincent; Bourgougnon, Nathalie; Mouget, Jean-Luc

    2017-02-01

    Natural alternatives antioxidant source has become a trending topic in the past decades to replace synthetic antioxidant. Microalgae have been mentioned to show interesting bioactive properties and one of them is its antioxidant activity. This study aims to evaluate the potential of three microalgae Dunaliella salina, Tetraselmis chuii and Isochrysis galbanaas new source of natural antioxidant. Proximate analysis and total phenolic content of D. salina, T. chuii and I. galbanas were determined. Antioxidant activity of methanolic extracts of these three species prepared in different concentration (50, 100, 250, 500, and 1000 ppm) was performed through DPPH assay. I. galbana clone Tahiti demonstrated a highest antioxidant potential with 61.64 of inhibition at 50 ppm followed by D. salina with 58.45 % of inhibition and T. chuii with 52.58 % of inhibition. I. galbana clone Tahiti was the best antioxidant with total phenol content of 17.798 mg GAE g-1 extract at 50 ppm; followed by T. chuii 16.868 mg GAE g-1 extract and the lowest was D. salina with 4.672 mg GAE g-1 extract. Results suggest that these microalgae posses antioxidant potential which could be considered for future applications in medicine, dietary supplements, cosmetics or food industries.

  2. Seed production and quality of maize in High Valleys of Mexico.

    Directory of Open Access Journals (Sweden)

    Juan Virgen-Vargas

    2015-12-01

    Full Text Available The objective of this study was to increase the productivity of maize in High Valleys of Mexico, at the Valley of México and Bajio Experimental Stations of the National Institute for Forestry, Agriculture and Livestock Research (INIFAP. The following activities were carried out: production of registered seed to strengthen seed micro- enterprises of national capital, quality evaluation of certified seed, and generation of production technology. Between 2005 and 2013, 46.71 tons of registered seed of the hybrids parents: H-40, H-48, H-50, H-52, H-66, H-70 and H-161, and the varieties: VS-22, V-54A and V-55A were produced and sold to 31 seed producers in the Estado de Mexico, Tlaxcala, Puebla, Hidalgo, Morelos, Guanajuato, Michoacan, and Jalisco; that satisfied 60 % of demand per year (8.68 t. In 2013 and 2014, agreements were signed between INIFAP and four micro-enterprises to produce registered seeds. The certified seed produced by companies reached certification standards, germination percentage ≥ 85, 98% pure seed and less than 2% inert matter; test weight between 72 and 78 kg/hl, thousand seed weight between 288 and 361 g and genetic quality between 96 and 98 % of the true type plants. The study identified information about locations, potential yields, population density, and planting dates for the production of parents, lines and single crosses, in the Estado de Mexico and Tlaxcala.

  3. Sexual maturity and performance of pullets fed different preparations and concentrations of brown marine algae (Sargassum dentifebium in pre-laying and early laying periods

    Directory of Open Access Journals (Sweden)

    Mohammed A. Al-Harthi

    2014-01-01

    Full Text Available The effect of brown marine algae (BMA; Sargassum dentifebium as alternative feed source for pullets was studied in three processed and at three concentrations in the pullets from 14-42 weeks. The processing forms were sundried brown marine algae (SBMA, sundried and boiled brown marine algae (BBMA and sundried and autoclaved brown marine algae (ABMA. The concentrations of BMA were 2%, 4% and 6% that composed 10 treatments along with control. Each treatment was replicated 6 times using 30 pullets per treatment. Different criteria on pullets and eggs, including feed intake, body weight, feed conversion efficiency, laying rate and egg mass and quality were studied. Results indicated that BMA could be used up to 6% in the pullets diets from 14 to 42 weeks without adverse effects (P≥0.05 on sexual maturity (139-142 days, laying rate (80.7-87.9%, egg mass (44.99-51.86 g/hen/day, feed conversion ratio (2.468-2.868 kg feed/kg egg and Haugh unit (82.9-90.6 and shell percentage (8.61-9.87%. Furthermore, egg yolk color and calcium content in eggshell were improved (P≤0.05 by 12.31% and 9.1%, respectively.

  4. Alteration of hydrogen metabolism of ldh-deleted Enterobacter aerogenes by overexpression of NAD+-dependent formate dehydrogenase.

    Science.gov (United States)

    Lu, Yuan; Zhao, Hongxin; Zhang, Chong; Lai, Qiheng; Wu, Xi; Xing, Xin-Hui

    2010-03-01

    The NAD+-dependent formate dehydrogenase FDH1 gene (fdh1), cloned from Candida boidinii, was expressed in the ldh-deleted mutant of Enterobacter aerogenes IAM1183 strain. The plasmid of pCom10 driven by the PalkB promoter was used to construct the fdh1 expression system and thus introduce a new dihydronicotinamide adenine dinucleotide (NADH) regeneration pathway from formate in the ldh-deleted mutant. The knockout of NADH-consuming lactate pathway affected the whole cellular metabolism, and the hydrogen yield increased by 11.4% compared with the wild strain. Expression of fdh1 in the ldh-deleted mutant caused lower final cell concentration and final pH after 16 h cultivation, and finally resulted in 86.8% of increase in hydrogen yield per mole consumed glucose. The analysis of cellular metabolites and estimated redox state balance in the fdhl-expressed strain showed that more excess of reducing power was formed by the rewired NADH regeneration pathway, changing the metabolic distribution and promoting the hydrogen production.

  5. Preparation of highly developed mesoporous activated carbon fiber from liquefied wood using wood charcoal as additive and its adsorption of methylene blue from solution.

    Science.gov (United States)

    Ma, Xiaojun; Zhang, Fan; Zhu, Junyan; Yu, Lili; Liu, Xinyan

    2014-07-01

    Activated carbon fiber (C-WACF) with super high surface area and well-developed small mesopores were prepared by liquefied wood and uses wood charcoal (WC) as additive. The characterization and properties of C-WACF were investigated by XRD, XPS and N2 adsorption. Results showed the pore development was significant at temperatures >750°C, and reached a maximum BET surface area (2604.7 m(2)/g) and total pore volume (1.433 cm(3)/g) at 850°C, of which 86.8% was from the contribution of the small mesopores of 2-4 nm. It was also found that the mesopore volume and methylene blue adsorption of C-WACF were highly increased as the temperature increases from 750 to 850°C. Additionally, the reduction of graphitic layers, the obvious changes of functional groups and the more unstable carbons on the surface of C-WACF, which played important roles in the formation of mesopores, were also observed.

  6. Age trends and within-site effects in wood density and radial growth in Quercus faginea mature trees

    Directory of Open Access Journals (Sweden)

    Vicelina B. Sousa

    2016-04-01

    Full Text Available Aim of the study: This paper aims to valorize the wood of Quercus faginea Lam. for high quality end uses (e.g. furniture by studying growth and quality properties using mature trees. Age trends in tree-ring width and wood density are shown and the main factors responsible for variations in tree-ring width and wood density within and between trees are investigated. Area of study: The study site is in the center of Portugal within the natural species distribution area.Material and methods: Radial samples from ten mature trees were collected at 6 heights (from base to 9.7 m and prepared for X-ray microdensity.Main results: Wood density showed high values, ranging from 0.868 g/cm3 to 0.957 g/cm3. Wood density decreased from pith to bark and with stem height. Cambial age showed a linear relationship with wood density and most of the variation in wood is explained by age. Intra-ring and axial within-tree homogeneity was good.Research highlights: Mature trees of Q. faginea showed high wood density and a high potential for high quality end uses, comparable to other oaks. Wood density is influenced by cambial age and tree-ring width. Wood quality may be improved by tree growth rates adjustment e.g. through an adequate tree stand density (e.g. thinning operations. 

  7. Coaxial fiber supercapacitor using all-carbon material electrodes.

    Science.gov (United States)

    Le, Viet Thong; Kim, Heetae; Ghosh, Arunabha; Kim, Jaesu; Chang, Jian; Vu, Quoc An; Pham, Duy Tho; Lee, Ju-Hyuck; Kim, Sang-Woo; Lee, Young Hee

    2013-07-23

    We report a coaxial fiber supercapacitor, which consists of carbon microfiber bundles coated with multiwalled carbon nanotubes as a core electrode and carbon nanofiber paper as an outer electrode. The ratio of electrode volumes was determined by a half-cell test of each electrode. The capacitance reached 6.3 mF cm(-1) (86.8 mF cm(-2)) at a core electrode diameter of 230 μm and the measured energy density was 0.7 μWh cm(-1) (9.8 μWh cm(-2)) at a power density of 13.7 μW cm(-1) (189.4 μW cm(-2)), which were much higher than the previous reports. The change in the cyclic voltammetry characteristics was negligible at 180° bending, with excellent cycling performance. The high capacitance, high energy density, and power density of the coaxial fiber supercapacitor are attributed to not only high effective surface area due to its coaxial structure and bundle of the core electrode, but also all-carbon materials electrodes which have high conductivity. Our coaxial fiber supercapacitor can promote the development of textile electronics in near future.

  8. The Economic Impact of Inflammatory Bowel Disease in Canada

    Directory of Open Access Journals (Sweden)

    Robert Hilsden

    2004-01-01

    Full Text Available Longobardi and colleagues examined the effect of inflammatory bowel disease (IBD on employment, using data from 10,891 respondents aged 20 to 64 years from the 1998 cycle of the Canadian National Population Health Survey (NPHS (1. This sample included 187 (1.7% subjects who self-reported IBD or a similar bowel disorder. A significantly greater proportion of IBD than non-IBD respondents reported that they were not in the labour force (28.9% versus 18.5%. Even after adjusting for other factors (age group, level of pain, etc, subjects with IBD had a 2.9% higher nonparticipation rate (21.4%. For example, among people not hospitalized within the past year and with no limitation of activities due to pain, IBD subjects were 1.2 times more likely to be unemployed than those without IBD. Subjects who reported high levels of pain had a very high probability of being out of the labour force. Based on Canadian annual compensation data for all employed persons in Canada, and age- and sex-specific prevalence, and incidence rates for IBD, the authors estimated that there are 119,980 IBD patients between the ages of 20 and 64 years in Canada and that this group includes 3479 people who are not in the labour force. This translates into lost wages of $104.2 million, or $868 per IBD patient

  9. A study of vitamin D levels and associated deficiency in pregnancy and its effect on maternal and fetal outcome

    Directory of Open Access Journals (Sweden)

    Anupama Dave

    2016-12-01

    Full Text Available Background: From conception the embryo is dependent on the mother for all nutritional requirements until birth. Vitamin D deficiencies have adverse effect on pregnancy outcome result in poor growth, prematurity, NTD, even congenital anomalies. The aim and objectives of the study was to assess the prevalence of deficiencies among pregnant woman attending M.Y. Hospital and assess the correlation with the pregnancy complications. Methods: Total 110 patients were studied for vitamin d levels and associated obstetrical complications and risk factors over a period of six months. 53 pregnant women were found to be deficient with vitamin D. Results: 53 pregnant women out of total of 110 were deficient in vitamin D levels. Maximum patients belonged to group (21-30yr of age. Vitamin D deficiency was more in housewives (65.3% and in urban(86.8%. Low birth weight<2.5kg were born 50(45.5% and 2 IUD. 2 were diagnosed NTD in USG reports. 80% low birth weight babies were born in vitamin D deficient women. Conclusions: Our study fails to show a causal relation between low vitamin D level and adverse maternal and fetal outcome in terms of preeclampsia, cesarean delivery, oligo and diabetes. There was a relation between vitamin D deficiency and low birth weight babies.

  10. Results of Cataract Outreach Services in a State of Nigeria

    Directory of Open Access Journals (Sweden)

    Abdu Lawan

    2010-06-01

    Full Text Available AIM: A blindness prevalence survey in 1996 indicated that estimates of 40000 are blind from cataracts in Kano state, northwestern Nigeria. Many more were severely visually impaired. Eye care personnel and other resources for eye care delivery are located at the state capital. The state Ministry of Health organized an outreach program. The aim was to operate on 750 cataract patients and measure the visual acuity at two weeks follow up. METHOD: Patients were registered and examined. Cataract patients with accurate four quadrant light projection, briskly reacting pupils and normal intra ocular pressures were selected and had manual extra capsular cataract extraction with posterior chamber intra ocular lens implantation. Post operative medications were administered. Patients were reviewed at 2 weeks follow up after discharge during which their visual acuity was measured and recorded. RESULTS: 868 cataract patients were operated. Thirty two percent of the patients were blind before surgery and 77% of these had bilateral cataracts. The proportion of those who had posterior chamber intra ocular lens (PC IOL was 85%. The proportion of patients who regained normal vision was 43% and overall, 94% had vision of 6/60 or, better after surgery compared with 20% in this category before surgery, (WHO vision category 0 and 1. CONCLUSION: Cataract outreach service is essential in reducing cataract blindness. There is need to follow up patients although the vision recorded for this study was obtained at two weeks follow up. [TAF Prev Med Bull 2010; 9(3.000: 225-228

  11. Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.

    Directory of Open Access Journals (Sweden)

    William M Brandler

    Full Text Available Humans display structural and functional asymmetries in brain organization, strikingly with respect to language and handedness. The molecular basis of these asymmetries is unknown. We report a genome-wide association study meta-analysis for a quantitative measure of relative hand skill in individuals with dyslexia [reading disability (RD] (n = 728. The most strongly associated variant, rs7182874 (P = 8.68 × 10(-9, is located in PCSK6, further supporting an association we previously reported. We also confirmed the specificity of this association in individuals with RD; the same locus was not associated with relative hand skill in a general population cohort (n = 2,666. As PCSK6 is known to regulate NODAL in the development of left/right (LR asymmetry in mice, we developed a novel approach to GWAS pathway analysis, using gene-set enrichment to test for an over-representation of highly associated variants within the orthologs of genes whose disruption in mice yields LR asymmetry phenotypes. Four out of 15 LR asymmetry phenotypes showed an over-representation (FDR ≤ 5%. We replicated three of these phenotypes; situs inversus, heterotaxia, and double outlet right ventricle, in the general population cohort (FDR ≤ 5%. Our findings lead us to propose that handedness is a polygenic trait controlled in part by the molecular mechanisms that establish LR body asymmetry early in development.

  12. Performance Test of Openflow Agent on Openflow Software-Based Mikrotik RB750 Switch

    Directory of Open Access Journals (Sweden)

    Rikie Kartadie

    2016-11-01

    Full Text Available A network is usually developed by several devices such as router, switch etc. Every device forwards data package manipulation with complicated protocol planted in its hardware. An operator is responsible for running configuration either to manage rules or application applied in the network. Human error may occur when device configuration run manually by operator. Some famous vendors, one of them is MikroTik, has also been implementing this OpenFlow on its operation. It provides the implementation of SDN/OpenFlow architecture with affordable cost. The second phase research result showed that switch OF software-based MikroTik resulted higher latency value than both mininet and switch OF software-based OpenWRT. The average gap value of switch OF software-based MikroTik is 2012 kbps lower than the value of switch OF software-based OpenWRT. The average gap value of throughput bandwidth protocol UDP switch OF software-based MikroTik is 3.6176 kBps lower than switch OF software-based OpenWRT and it is 8.68 kBps lower than mininet. The average gap throughput jitter protokol UDP of switch OF software-based MiktoTik is 0.0103ms lower than switch OF software-based OpenWRT and 0.0093ms lower than mininet. 

  13. Continuous feed medication with nitroscanate for the removal of Hymenolepis nana in naturally infected mice and rats.

    Science.gov (United States)

    Gönenç, B; Sarimehmetoğlu, H O

    2001-10-01

    In this study, the effects of nitroscanate were investigated in naturally acquired Hymenolepis nana infections in rats and mice. The natural infection was determined by centrifugal flotation technique of faeces. The infected rats and mice were divided into two treatment and two control groups (N = 10). Nitroscanate at the dose of 50 mg/kg per day was given in the diet for 4 days. The rats and mice of treatment groups were necropsied on 7th day after the last treatment together with those of control groups. Following necrospsy, in the treatment group a geometric mean of 1.07 Hymenolepis nana were recovered out of ten mice, compared with 8.14 in the control group. In the rat treatment group no Hymenolepis nana were found in ten rats, while the control group showed a geometric mean of 6.23. Nitroscanate was found to be effective 100% and 86.8% at the treatment of H. nana infection in rats and mice respectively.

  14. Arsenic and selenium speciation in coal fly ash extracts by ion chromatography-inductively coupled plasma mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, B.P.; Miller, W.P. [University of Georgia, Aiken, SC (United States). Savannah River Ecology Lab.

    1998-10-01

    Ion chromatography (IC) coupled to inductively coupled plasma mass spectrometry (ICP-MS) was used to determine As(III), As(V), Se(IV), and Se(VI) in aqueous extracts of coal fly ash. Because all species were fully resolved, the resulting chromatograms were obtained by summing signal intensities for m/z 75 + m/z 82. Absolute detection limits of 7.2, 87, 117 and 28 pg for As(III), Se(IV), Se(VI), and As(V) respectively, were obtained corresponding to 0.072, 0.868, 1.174, and 0.284 {mu} gl{sup -1} for 100 {mu} l injection volume. The technique was used to determine the speciation of As and Se in aqueous extracts of 24 coal fly ash samples including NIST SRM 1633 b. The predominant species were As(V) and Se(IV), with As(III) detected in two low pH fly ashes. Extraction of fly ashes at pH 5 altered the concentrations of total soluble As and Se but did not affect the predominant As and Se speciation.

  15. Convergent validity between SF-36 and WHOQOL-BREF in older adults

    Science.gov (United States)

    Castro, Paula Costa; Driusso, Patrícia; Oishi, Jorge

    2014-01-01

    OBJECTIVE To compare the reliability and convergent validity of instruments assessing quality of life in Brazilian older adults. METHODS Cross-sectional study of 278 literate, community-dwelling older adults attending a municipal university for the elderly in Sao Carlos, SP, Southeastern Brazil between 2006 and 2008. The Brazilian versions of the SF-36 and WHOQOL-BREF instruments to assess quality of life were compared. Cronbach’s alpha coefficient was used to estimate reliability and Pearson’s correlation for comparison between the two scales. RESULTS Most of participants were women (87.8%) with a mean age of 63.83±7.22 years. Both scales showed an acceptable internal consistency – WHOQOL-BREF Cronbach’s alpha was 0.832 and SF-36 was 0.868. There was a weak (r ≤ 0.6) correlation between the related fields in the two questionnaires. CONCLUSIONS The SF-36 and WHOQOL-BREF are reliable instruments for clinical and research uses in Brazilian older women. To select one, researchers should consider which aspects of quality of life they aim to capture because of weak convergent validity signs. This study’s results indicate that WHOQOL-BREF may be more relevant to evaluate changes in the quality of life of older women because it prioritizes responses to the aging process and avoids focusing on impairment. PMID:24789638

  16. Crystallographic Characterization of the Novel Inorganic-organic Hybrid Coordinated Polymer:[(C22H50N2)(Ag2I4)]n

    Institute of Scientific and Technical Information of China (English)

    李浩宏; 陈之荣; 黄长沧; 肖光参; 任永刚

    2004-01-01

    A novel coordinated polymer [(C22H50N2)(Ag2I4)]n([C22H50N2]2+ = N,N′-1,2- ethylence-bis(N,N′-dimethyl octane ammonium) (EDO)) was synthesized by the reaction of AgI and EDO at room temperature with pH = 6.8, and structurally characterized by means of X-ray single- crystal diffraction. It crystallizes in triclinic, space group P1 with a = 9.6080(1), b = 12.7643(2), c = 7.2157(8)A,α = 100.835(8), β = 91.030(3), γ = 91.297(9)°, (C21.50H48.50Ag2I4N2), Mr = 1058.46, V = 868.71(19)A3, Z = 1, Dc = 2.023g/cm3, F(000) = 497.5, μ(MoKα) = 4.692 mm-1, the final R = 0.0623 and wR = 0.1949 for 2641 observed reflections with I > 2((I). The title compound consists of cations ([C22H50N2]2+) and anion chain (Ag2I42-)∞ which are combined by static attracting forces in the crystal to form the so-called organic-inorganic hybrid material.

  17. 2008年卢龙县医院妇科门诊病人阴道念珠菌感染情况调查%Survey of Vaginal Candidasis Infection among Outpatients of Gynecology Department of Lulong County Hospital

    Institute of Scientific and Technical Information of China (English)

    李晓青

    2010-01-01

    目的 了解卢龙县医院妇科门诊阴道念珠菌感染情况.方法 采用生理盐水直接涂片法检查2008年卢龙县医院1869例妇科门诊病人的阴道分泌物,了解阴道念珠菌感染情况,对检查结果进行分析.结果 1 868例病人中阴道念珠菌感染329例,发病率为17.60%;40岁~年龄组感染率(28.35%)明显高于其他年龄组,35岁~年龄组感染率为26.90%;1、3、4月感染率较高,分别为21.34%、23.25%、21.05%;不良的卫生习惯和滥用广谱抗生素与阴道念珠菌感染的发生有一定的关系.结论 卢龙县阴道念珠菌感染率较高,应对阴道念珠菌感染病人在积极治疗的同时更应加强预防保健工作.

  18. Assessment of the DNA Damage in Human Sperm and Lymphocytes Exposed to the Carcinogen Food Contaminant Furan with Comet Assay

    Directory of Open Access Journals (Sweden)

    Dilek Pandir

    2015-10-01

    Full Text Available ABSTRACTThe aim of this work was to assess the damage of DNA in human blood cell and spermin vitro under the influence of furan. These cells were administered 0-600 μM of furan at 37 and 32oC for 30 and 60 min, respectively. A significant increase in tail DNA%, tail length and moment indicating DNA damage was observed at increasing doses when compared to the controls. The treatment with 300 and 600 μM of furan showed a maximum increase of 86.74 ± 2.43 and 93.29 ± 8.68 compared to the control tail DNA% in lymphocytes. However, only 600 μM of furan showed a maximum increase of 94.71 ± 6.24 compared to the control tail DNA% in sperm. The results suggested that furan caused DNA damage in lymphocytes at increasing doses, but appeared to have not the same effect on human sperm at the low doses. Genotoxic activity had an impact on the risk assessment of furan formed on the food for human cells. Therefore, it would be important to further investigate these properties of furan as the food mutagen.

  19. [ANTIBIOTIC RESISTANCE OF SALMONELLA SPP. ISOLATED IN THE TERRITORY OF THE KRASNOIARSK REGION].

    Science.gov (United States)

    Reshetneva, I T; Per'ianova, O V; Dmitrieva, G M; Ostapova, T S

    2015-01-01

    There were studied Salmonella spp. isolated from various objects (sick patients, bacteria carriers, food, sewages) in the Krasnoyarsk region. Susceptibility to antimicrobial drugs was estimated with disc diffusion method. Bacterial cultures form sick patients were highly susceptible to aminoglycosides (amikacin and gentamicin)--susceptible strains accounted for 98-99%, carbapenems (imipenem)--100%, cephalosporins (cephtriaxone)--97.8%, fluoroquinolones (ophloxacin)--95.8%, quinolones (ciprofloxacin)-- 88.9%, chloramphenicol--86.8%. Salmonella showed lesser susceptibility to sulphamethoxazole/trimethoprim 81.4%. Ampicillin--73.6% inhibitor protected antibiotic amoxicillin/clavulanic acid--86.4%. Salmonella spp. are the most resistant to tetracycline, the proportion of susceptible strains was less than a third--22.1%. The comparison of resistance of serovar S. enterica Enteritidis. with other serologic strains 'of S. enterica (S. Typhimurium, S. Infantis, S. Tshiongtve, S. Agama et al.) revealed greater resistance of anot Eneteritidis)) isolates to ampicillin, amoxicillin/ clavulanic acid,. ciprofloxacin and greater differences in resistance were to ofloksacin and, co-trimoxasol. The most high resistance ofthe all serovars S. enterica is to tetracycline (S. Enteritidis--26.2%, "non Enteritidis"--9.1%). Thus salmonella circulating in the Krasnoyarsk region are characterized by susceptibility to the most of antimicrobial drugs. The high resistance of islitates is revealed to tetracycline, ampicillin and sulfonamides.

  20. Optimization of ultrasonic-assisted extraction and radical-scavenging capacity of phenols and flavonoids from Clerodendrum cyrtophyllum Turcz leaves.

    Directory of Open Access Journals (Sweden)

    Jing Zhou

    Full Text Available Ultrasonic-assisted extraction (UAE was developed to extract phenolic and flavonoid antioxidants from Clerodendrum cyrtophyllum Turcz leaves. The optimal experimental parameters for antioxidant extraction from C. cyrtophyllum leaves were measured using single-factor experimentation combined with response surface methodology (RSM. Total phenolic content (TPC and total flavonoid content (TFC assays were used to quantify antioxidant compounds. Next, antioxidant radical scavenging capacity was measured using 2,2'-diphenyl-1-picrylhydrazyl (DPPH and 2,2' -azino-bis(3-ethylbenzothiazoline-6-sulphonicacid (ABTS radicals. Optimized extraction conditions for UAE from C. cyrtophyllum leaves were as follows: 60.9% ethanol, 85.4 min, and 63.3°C for maximal TPC extraction (16.8 ± 0.2 mg GAE/g DW; 67.7% ethanol, 82.9 min, and 63.0 °C for maximal TFC extraction (49.3 ± 0.4 mg RT/g DW; 48.8% ethanol, 85.1 min, and 63.9 °C for maximal DPPH radical-scavenging capacity (86.8 ± 0.2%; and 50.6% ethanol, 81.3 min, and 63.4 °C for maximal ABTS radical-scavenging capacity (92.9 ± 0.5%. Ethanol concentration was the most important factor in the extraction process. Our work offers optimal extraction conditions for C. cyrtophyllum as a potential source of natural antioxidants.

  1. Experimental study of discharging PCM ceiling panels through nocturnal radiative cooling

    DEFF Research Database (Denmark)

    Bourdakis, Eleftherios; Péan, Thibault Q.; Gennari, Luca;

    for the solar and the PCM loops, for five days each. The highest examined water flow rate (210 l/h) in the PCM loop provided the best thermal environment in the climate chamber, namely 92% of the occupancy time was within the range of Category III of Standard EN 15251. Although the lowest examined water flow...... rate (96 l/h) in the solar loop provided the highest average cooling power, due to the significant variations in the weather conditions during the three experimental cases, made it impossible to determine to which extent the difference in the cooling power is due to the different water flow rate....... The percentage of electrical energy use that could be covered from the PV/Ts on site was 71.5% for Case 1, 68.3% for Case 2 and 86.8% for Case 3. In any case, the PV/T panels proved to be an efficient solution for the production of electrical energy, heated and chilled water....

  2. A meta-analysis study of the effect of chilling on prevalence of Salmonella on pig carcasses.

    Science.gov (United States)

    Gonzales Barron, U; Bergin, D; Butler, F

    2008-07-01

    In the field of food safety, meta-analysis can be used to combine results of prevalence studies of pathogens at critical stages within the food processing chain so that policy makers can access reliable and concise information on the effectiveness of interventions for controlling and preventing foodborne illnesses in humans. The objective of this work was to demonstrate the applicability of a parametric approach of meta-analysis to the specific case of determining the overall effect of chilling on Salmonella prevalence on pig carcasses. A meta-analysis was performed on each of two parameters measuring effect size for binary outcomes (relative risk and risk difference). Both meta-analyses confirmed that the chilling operation has a significant beneficial effect (P pig carcasses. Because risk difference is a parameter sensitive to the differences across studies in carcass swab areas and Salmonella detection methods, its meta-analysis highly reflected this heterogeneity (P meta-analysis solution, which is deemed more suitable for compilations based on a small number of individual studies (n = 9). Because of the systematic approach of meta-analysis (i.e., individual studies are weighed according to precision) and its reliance for actual data, the output distribution of the relative risk effect size (approximately eN(-0.868,0.166)) merits consideration for inclusion in the chilling stage of quantitative risk assessments modeling the prevalence of this pathogen along the pork production chain.

  3. Results of the third reproductive assessment survey of North American Asian (Elephas maximus) and African (Loxodonta africana) female elephants.

    Science.gov (United States)

    Dow, T L; Holásková, I; Brown, J L

    2011-01-01

    A written survey assessed reproductive status of female Asian and African elephants in AZA/SSP facilities in 2008, and data were compared to surveys conducted in 2002 and 2005. Results showed that ovarian acyclicity rates across the surveys remained unchanged for Asian (13.3, 10.9 and 11.1%) and African (22.1, 31.2 and 30.5%) elephants, respectively (P > 0.05), but were higher overall for African compared to Asian elephants (P elephants with irregular cycles (14.3 and 15.8%) and irregular + no cycles (25.4 and 46.4%) was similar to 2005 (7.6 and 11.8%; 18.5 and 43.0%), but were increased compared to 2002 (2.6 and 5.2%; 16.0 and 27.3%), respectively (P elephants compared to females at facilities with no male, respectively. Cyclicity rates were higher for Asian (86.8 vs. 65.2%) and African (67.9 vs. 56.7%) elephants managed in free compared to protected contact programs (P 0.05). In summary, incidence of ovarian cycle problems continues to predominantly affect African elephants. Although percentages of acyclicity did not increase between 2005 and 2008, 42.2% Asian and 30.2% African females were no longer being hormonally monitored; thus, reproductive cycle abnormalities could be worse than current data suggest.

  4. Survival and prognostic factors in non-small cell lung cancer patients with spinal bone metastases. A retrospective analysis of 303 patients

    Energy Technology Data Exchange (ETDEWEB)

    Rief, H.; Welzel, T.; Rieken, S.; Bischof, M.; Lindel, K.; Combs, S.E.; Debus, J. [University Hospital of Heidelberg, Department of Radiation Oncology, Heidelberg (Germany); Muley, T. [University Hospital of Heidelberg, Thorax Clinic, Department of Thoracic Oncology, Heidelberg (Germany); Bruckner, T. [University Hospital of Heidelberg, Department of Medical Biometry, Heidelberg (Germany)

    2014-01-15

    For palliative care of spinal bone metastases, stability assessment is of crucial importance. Pathological fractures, instability-related patient immobility and the extent of bone metastasis have been reported to affect patient outcome and these parameters have therefore been used for treatment stratification. We report on stability-dependent fracture and survival rates in over 300 non-small cell lung cancer (NSCLC) patients. Data from 303 patients with 868 osteolytic metastases treated with radiotherapy (RT) between 2000 and 2012 were evaluated retrospectively. In NSCLC patients with bone metastases only, the retrospective 6- and 12-month overall survival (OS) rates were 76.7 and 47.2%, respectively. In patients with additional non-bone distant metastases, these values were 60.0 and 34.0%, respectively. Survival rates were significantly lower in patients with multiple bone metastases and in those suffering pathological fractures (p=0.017). No significant impact of histological type, location of spinal lesions or treatment regime was detected. Furthermore, stability assessment revealed no influence of vertebral column stability on patient outcome (p=0.739). Our analysis demonstrated a correlation between the pathological fractures of bone lesions, the number of bone metastases, additional distant metastases and survival. The results offer a rationale for future prospective investigations. (orig.)

  5. Appearance and distribution of regioisomers in metallo- and serine-protease-catalysed acylation of sucrose in N,N-dimethylformamide

    DEFF Research Database (Denmark)

    Lie, Aleksander; Meyer, Anne S.; Pedersen, Lars Haastrup

    2014-01-01

    The appearance and distribution of monoester regioisomers were investigated in the virtually irreversible acylation of sucrose with the enol ester, vinyl laurate, as acyl donor catalysed by serine proteases and a metalloprotease in the hydrophilic, aprotic solvent N,N-dimethylformamide. Sucrose......-Lauroyl sucrose was the most abundant monoester regioisomer synthesised and the highest concentration observed was 23.7 mM after 24 h in the thermolysin-catalysed reaction. The highest concentration of 2-O-lauroyl sucrose detected in the reaction catalysed by ALP-901 was 19.0 mM, while it was 17.0 m...... 48 h (2:3:4:6:1:3) was 72:5:2:1:7:14 in the reaction catalysed by ALP-901, and 74:5:2:1:7:13 in the reaction without protein. In the reaction catalysed by thermolysin the distribution was 71:5:2:–:9:13 after 6 h and 86:8:–:–:4:3 after 48 h of reaction. The esterification of sucrose with vinyl laurate...

  6. Disc displacement patterns in lumbar anterior spondylolisthesis: Contribution to foraminal stenosis

    Energy Technology Data Exchange (ETDEWEB)

    MacMahon, P.J. [Department of Radiology, Cappagh National Orthopaedic Hospital, Finglas, Dublin 11 (Ireland)], E-mail: petermacmahon@yahoo.com; Taylor, D.H.; Duke, D.; Brennan, D.D.; Eustace, S.J. [Department of Radiology, Cappagh National Orthopaedic Hospital, Finglas, Dublin 11 (Ireland)

    2009-04-15

    Purpose: To describe the particular disc displacement pattern seen at MRI in patients with spondylolisthesis, and its potential contribution to foraminal stenosis. Methods: 38 patients with symptomatic lumbar anterior spondylolisthesis and 38 sex and aged matched control patients with herniated disc disease, at corresponding disc space levels, were included for study. In each case note was made of the presence, absence and direction of disc displacement and also the presence and location of neural contact with the displaced disc. Results: In 33 of 38 (86.8%) patients in the spondylolisthesis group, the vertical disc displacement was upward. In the control group only 3 patients (7.8%) had upward vertical disc displacement. 19 patients (53%) from the spondylolisthesis group had exit foraminal nerve root contact, compared to 7 patients (18.4%) from the control group. 27 control patients (71%) had contact within the lateral recess, compared to only 6 patients (17%) with spondylolisthesis. Differences for upward displacement were significant (p < 0.05). Conclusion: Disc displacement in patients with spondylolisthesis is predominately in a cephalad and lateral direction. Although this disc displacement pattern can occur in patients without spondylolisthesis, its incidence is much greater in the subset of patients with concomitant spondylolisthesis. In the setting of acquired osseous narrowing of the exit foramen, this described pattern of disc displacement superiorly and laterally in spondylolisthesis increases the susceptibility of spondylolisthesis patients to radicular symptoms and accounts for the exiting nerve root being more commonly affected than the traversing nerve root.

  7. Early association of electrocardiogram alteration with infarct size and cardiac function after myocardial infarction

    Institute of Scientific and Technical Information of China (English)

    陶则伟; 黄元伟; 夏强; 傅军; 赵志宏; 陆贤; BRUCEI.C.

    2004-01-01

    Objective:Myocardial infarction (MI) is the main cause of heart failure, but the relationship between the extent of MI and cardiac function has not been clearly determined.The present study was undertaken to investigate early changes in the electrocardiogram associated with infarct size and cardiac function after MI. Methods: MI was induced by ligating the left anterior descending coronary artery in rats. Electrocardiograms, echocardiographs and hemodynamic parameters were assessed and myocardial infarct size was measured from mid-transverse sections stained with Masson's trichrome. Results:The sum of pathological Q wave amplitudes was strongly correlated with myocardial infarct size (r=0.920, P<0.0001), left ventricular ejection fraction (r=-0.868, P<0.0001) and left ventricular end diastolic pressure (r=0.835, P<0.0004).Furthermore, there was close relationship between MI size and cardiac function as assessed by left ventricular ejection fraction (r=-0.913, P<0.0001) and left ventricular end diastolic pressure (r=0.893, P<0.0001).Conclusion: The sum of pathological Q wave amplitudes after MI can be used to estimate the extent of MI as well as cardiac function.

  8. Identification of hepatitis B virus subgenotype A3 in rural Gabon.

    Science.gov (United States)

    Makuwa, Maria; Souquière, Sandrine; Telfer, Paul; Apetrei, Cristian; Vray, Muriel; Bedjabaga, Issa; Mouinga-Ondeme, Augustin; Onanga, Richard; Marx, Preston A; Kazanji, Mirdad; Roques, Pierre; Simon, François

    2006-09-01

    An hepatitis B virus (HBV) molecular survey was conducted in five remote villages in the equatorial forest in Gabon, Central Africa. Two hundred seventy out of 311 inhabitants (86.8%) were HBV-infected or had evidence of past HBV infection. Chronic hepatitis corresponding to hepatitis B surface antigen (HBsAg) positivity was suspected in 27 (8.6%) of the HBV-infected subjects. High HBV viral loads were detected mainly in children aged 4-7 years. The pre-S/S domains were sequenced in 13 cases and 12 strains belonged to HBV-A genotype. In one case we found evidence for recombination between genotypes A and E. Phylogenetic analysis revealed that Gabonese HBV strains were distinct from HBV-A subgenotypes (A1 and A2). These new HBV strains from Gabon clustered with previously reported HBV-A3 subgenotype strains from Cameroon and Democratic Republic of Congo. The analysis of the pre-S2 domain allowed us to determine two amino acid substitutions (N/152/S and N/174/T) specific to the Central African HBV-A3 subgenotype strains and one amino acid substitution (P/155/Q) unique to these new Gabonese HBV-A3 subgenotype isolates. Two full genome sequences of two new Gabonese HBV isolates are also presented and confirm the distinctive HBV-Gab-A3 cluster.

  9. Many-body Expanded Analytical Potential Energy Function for Ground State PuOH Molecule

    Institute of Scientific and Technical Information of China (English)

    LI Yue-Xun; GAO Tao; ZHU Zheng-He

    2006-01-01

    Using the density functional method B3LYP with relativistic effective core potential (RECP) for Pu atom, the low-lying excited states (4∑+, 6∑+, 8∑+) for three structures of PuOH molecule were optimized. The results show that the ground state is X6∑+of the linear Pu-O-H (C∞v), its corresponding equilibrium geometry and dissociation energy are RPu-O=0.20595 nm, RO-H=0.09581 nm and -8.68 eV, respectively. At the same time, two other metastable structures [PuOH (Cs) and H-Pu-O (C∞v)] were found. The analytical potential energy function has also been derived for whole range using the many-body expansion method. This potential energy function represents the considerable topographical features of PuOH molecule in detail, which is adequately accurate in the whole potential surface and can be used for the molecular reaction dynamics research.

  10. The Incidence of Hepatocellular Carcinoma after Balloon-Occluded Retrograde Transvenous Obliteration

    Directory of Open Access Journals (Sweden)

    Keiji Yokoyama

    2015-01-01

    Full Text Available Balloon-occluded retrograde transvenous obliteration (BRTO is a highly effective therapy for gastric varices with liver cirrhosis. We have investigated the incidence of hepatocellular carcinoma (HCC after BRTO. We enrolled 71 patients with viral hepatitis in which HCC had not appeared with liver imaging findings at the time of BRTO. The overall survival rate after BRTO was 86.8%, 76.1%, and 50.5% at 1, 3, and 5 years. The occurrence rate of HCC after BRTO was 20.9%, 41.1%, and 60.7% at 1, 3, and 5 years, especially showing a higher occurrence of HCC at one year. Meanwhile, the occurrence rate of HCC after treatment which excluded BRTO for esophagogastric varices in patients was 6.3%, 19.2%, and 42.5% at 1, 3, and 5 years. The log-rank test revealed that the occurrence rate of HCC after treatment was significantly higher in the BRTO group compared with that in the non-BRTO group (P=0.0447. The recurrence rate of HCC after BRTO was 35.8% and 80.0% at 1 and 3 years. The present study demonstrated a high incidence of HCC after BRTO in liver cirrhosis patients with viral hepatitis infection. We have suggested the potential for BRTO to accelerate hepatocarcinogenesis.

  11. Structured chaos in a devil's staircase of the Josephson junction

    Science.gov (United States)

    Shukrinov, Yu. M.; Botha, A. E.; Medvedeva, S. Yu.; Kolahchi, M. R.; Irie, A.

    2014-09-01

    The phase dynamics of Josephson junctions (JJs) under external electromagnetic radiation is studied through numerical simulations. Current-voltage characteristics, Lyapunov exponents, and Poincaré sections are analyzed in detail. It is found that the subharmonic Shapiro steps at certain parameters are separated by structured chaotic windows. By performing a linear regression on the linear part of the data, a fractal dimension of D = 0.868 is obtained, with an uncertainty of ±0.012. The chaotic regions exhibit scaling similarity, and it is shown that the devil's staircase of the system can form a backbone that unifies and explains the highly correlated and structured chaotic behavior. These features suggest a system possessing multiple complete devil's staircases. The onset of chaos for subharmonic steps occurs through the Feigenbaum period doubling scenario. Universality in the sequence of periodic windows is also demonstrated. Finally, the influence of the radiation and JJ parameters on the structured chaos is investigated, and it is concluded that the structured chaos is a stable formation over a wide range of parameter values.

  12. 奶牛瑟氏泰勒虫P33表面蛋白基因的克隆及序列分析%Cloning and sequence analysis of the dairy COW Theileria sergenti P33 surface protein gene

    Institute of Scientific and Technical Information of China (English)

    曹世诺; 于龙政; 薛书江; 贾立军; 柴方红; 张守发

    2008-01-01

    研究根据GenBank上发表的牛瑟氏泰勒虫P33表面蛋白的基因序列设计合成1对引物,用PCR方法扩增出了牛瑟氏泰勒虫的基因片段,将该基因纯化后连接到pMDl8-T栽体上,进行序列测定和分析,并用此方法对延边某奶牛场10头奶牛进行了检测.结果表明:10份样品中9份为阳性,所扩增的目的基因核苷酸长为868 bp,共编码283个氨基酸;该段基因片段与牛泰勒虫韩国株核苷酸序列同源性为99.4%,氨基酸同源性为99.3%.

  13. 牛瑟氏泰勒虫P33表面蛋白基因的克隆及在大肠杆菌中的表达%Cloning of P33 surface protein gene of cow Theileria sergenti and its expression in E. coli

    Institute of Scientific and Technical Information of China (English)

    曹世诺; 于龙政; 薛书江; 周末; 刘廷; 张守发

    2009-01-01

    应用PCR方法扩增了牛瑟氏泰勒虫吉林株P33表面蛋白基因片段,并将扩增产物与pMD18-T载体连接,重组质粒经PCR、双酶切鉴定后测序;构建P33重组pGEX-4T-3表达载体,转化大肠杆菌BL-21,经IPTG诱导表达后.进行SDS-PAGE、免疫印记分析.结果显示,获得P33基因完整开放阅读框长868 bp,编码292个氨基酸,与中国株同源性为99.1%;表达的融合蛋白相对分子质量为59 000,能被牛瑟氏泰勒虫阳性血清识别,表明该融合蛋白具有较好的免疫原性.

  14. Serum Osteopontin Level Correlates with Carotid-Femoral Pulse Wave Velocity in Geriatric Persons

    Directory of Open Access Journals (Sweden)

    Chung-Jen Lee

    2014-01-01

    Full Text Available Osteopontin (OPN is involved in the regulation of vascular calcification processes. The aim of this study was to evaluate the relationship between fasting serum OPN concentration and carotid-femoral pulse wave velocity (cfPWV in geriatric persons. Fasting blood samples were obtained from 93 geriatric persons. cfPWV were performed by SphygmoCor system. Serum OPN levels were measured using a commercially available enzyme-linked immunosorbent assay. Geriatric adults who had diabetes (P=0.007 or dyslipidemia (P=0.029 had higher cfPWV levels than those without diabetes or dyslipidemia. The univariable linear regression analysis showed that age (P=0.002, waist circumference (P=0.048, body mass index (P=0.004, systolic blood pressure (P=0.001, diastolic blood pressure (P=0.036, pulse pressure (P=0.017, creatinine (P=0.002, and log-OPN level (P=0.001 were positively correlated with cfPWV levels, while the high-density lipoprotein cholesterol (HDL-cholesterol level (P=0.007 and glomerular filtration rate (P=0.001 were negatively correlated with cfPWV levels among the geriatric adults. Multivariable forward stepwise linear regression analysis of the significant variables also showed that log-OPN (β=0.233, R2=0.123, regression coefficient: 1.868, P=0.011 was still an independent predictor of cfPWV levels in geriatric persons.

  15. Reproductive outcome and survival of common bottlenose dolphins sampled in Barataria Bay, Louisiana, USA, following the Deepwater Horizon oil spill.

    Science.gov (United States)

    Lane, Suzanne M; Smith, Cynthia R; Mitchell, Jason; Balmer, Brian C; Barry, Kevin P; McDonald, Trent; Mori, Chiharu S; Rosel, Patricia E; Rowles, Teresa K; Speakman, Todd R; Townsend, Forrest I; Tumlin, Mandy C; Wells, Randall S; Zolman, Eric S; Schwacke, Lori H

    2015-11-01

    Common bottlenose dolphins (Tursiops truncatus) inhabit bays, sounds and estuaries across the Gulf of Mexico. Following the Deepwater Horizon oil spill, studies were initiated to assess potential effects on these ecologically important apex predators. A previous study reported disease conditions, including lung disease and impaired stress response, for 32 dolphins that were temporarily captured and given health assessments in Barataria Bay, Louisiana, USA. Ten of the sampled dolphins were determined to be pregnant, with expected due dates the following spring or summer. Here, we report findings after 47 months of follow-up monitoring of those sampled dolphins. Only 20% (95% CI: 2.50-55.6%) of the pregnant dolphins produced viable calves, as compared with a previously reported pregnancy success rate of 83% in a reference population. Fifty-seven per cent of pregnant females that did not successfully produce a calf had been previously diagnosed with moderate-severe lung disease. In addition, the estimated annual survival rate of the sampled cohort was low (86.8%, 95% CI: 80.0-92.7%) as compared with survival rates of 95.1% and 96.2% from two other previously studied bottlenose dolphin populations. Our findings confirm low reproductive success and high mortality in dolphins from a heavily oiled estuary when compared with other populations. Follow-up studies are needed to better understand the potential recovery of dolphins in Barataria Bay and, by extension, other Gulf coastal regions impacted by the spill.

  16. CHARACTERISTICS, STABILITY AND ANTIMICROBIAL ACTIVITY OF LACTIC ACID BACTERIA (Leuconostoc sp ISOLATED FROM BROILER’S CAECUM DURING STORAGE

    Directory of Open Access Journals (Sweden)

    S. Sumarsih

    2014-10-01

    Full Text Available Lactic acid bacteria (LAB is one of the natural microbe which widely used as fermentation agents.The purpose of this study was to examine the characteristics, stability and antimicrobial properties oflactic acid bacteria (Leuconostoc sp isolated from broiler’s caecum during storage. This research wasconducted by the Complete Randomized Design with 4 treatments (time of storage: 0, 2, 4 dan 6 weekswith 12 replications. Parameters observed were total number and stability properties of Leuconostoc spisolate which known as lactic acid bacteria. The results obtained total number of Leuconostoc sp isolatewere significantly (P<0.05 decreased from 8 x 107 to 1 x 103 Colony Forming Unit (CFU/mL duringstorage. Stability properties of Leuconostoc sp isolate were not affected by the time of storage.Antimicrobial activity of Leuconostoc sp were significantly (P<0.05 decreased from 9.94 to 8.68, 7.23and 6.14 mm during storage at 2, 4 and 6 weeks.

  17. A study of the population of Paraguay through isonymy.

    Science.gov (United States)

    Dipierri, José; Rodriguez-Larralde, Alvaro; Alfaro, Emma; Scapoli, Chiara; Mamolini, Elisabetta; Salvatorelli, Germano; Caramori, Graziano; De Lorenzi, Sonia; Sandri, Massimo; Carrieri, Alberto; Barrai, Italo

    2011-11-01

    In order to describe the isonymic structure of Paraguay, the distribution of 4,843,868 surnames of 2,882,163 persons was studied in the 18 departments and 237 districts of the nation. The correlations between isonymic and geographic distances for departments were r = 0.713 ± 0.052 for Euclidean distance, 0.597 ± 0.074 for Nei's and 0.582 ± 0.076 for Lasker's, and for districts r = 0.320 ± 0.007, 0.235 ± 0.009 and 0.422 ± 0.008, respectively. Average α was 151 for the entire country, 140.6 ± 6.5 for departments and 108.2 ± 2.7 for districts. The geographical distribution of districts'α is compatible with the settlement of subsequent groups of migrants moving from South towards the Centre and North of Paraguay. The geographical analysis of the first three components of Lasker's isonymy distance matrix is in agreement with such a process. The prevalence of Spanish-Amerindian ethnic groups and the relative absence of indigenous surnames (absence due mainly to the forced surname change of 1848) is in agreement with the diffusion of Spanish speaking males over a low-density area populated by indigenous groups. The present distribution of Y-markers and mt-markers in the available studies in most Latin American populations is compatible with this process.

  18. Global transcriptional start site mapping using differential RNA sequencing reveals novel antisense RNAs in Escherichia coli.

    Science.gov (United States)

    Thomason, Maureen K; Bischler, Thorsten; Eisenbart, Sara K; Förstner, Konrad U; Zhang, Aixia; Herbig, Alexander; Nieselt, Kay; Sharma, Cynthia M; Storz, Gisela

    2015-01-01

    While the model organism Escherichia coli has been the subject of intense study for decades, the full complement of its RNAs is only now being examined. Here we describe a survey of the E. coli transcriptome carried out using a differential RNA sequencing (dRNA-seq) approach, which can distinguish between primary and processed transcripts, and an automated prediction algorithm for transcriptional start sites (TSS). With the criterion of expression under at least one of three growth conditions examined, we predicted 14,868 TSS candidates, including 5,574 internal to annotated genes (iTSS) and 5,495 TSS corresponding to potential antisense RNAs (asRNAs). We examined expression of 14 candidate asRNAs by Northern analysis using RNA from wild-type E. coli and from strains defective for RNases III and E, two RNases reported to be involved in asRNA processing. Interestingly, nine asRNAs detected as distinct bands by Northern analysis were differentially affected by the rnc and rne mutations. We also compared our asRNA candidates with previously published asRNA annotations from RNA-seq data and discuss the challenges associated with these cross-comparisons. Our global transcriptional start site map represents a valuable resource for identification of transcription start sites, promoters, and novel transcripts in E. coli and is easily accessible, together with the cDNA coverage plots, in an online genome browser.

  19. A 220-1100 MHz low phase-noise frequency synthesizer with wide-band VCO and selectable I/Q divider

    Science.gov (United States)

    Hua, Chen; Renjie, Gong; Xu, Cheng; Yulin, Zhang; Zhong, Gao; Guiliang, Guo; Yuepeng, Yan

    2014-12-01

    This paper presents a low phase-noise fractional-N frequency synthesizer which provides an in-phase/quadrature-phase (I/Q) signal over a frequency range of 220-1100 MHz for wireless networks of industrial automation (WIA) applications. Two techniques are proposed to achieve the wide range. First, a 1.4-2.2 GHz ultralow gain voltage-controlled oscillator (VCO) is adopted by using 128 tuning curves. Second, a selectable I/Q divider is employed to divide the VCO frequency by 2 or 3 or 4 or 6. Besides, a phase-switching prescaler is proposed to lower PLL phase noise, a self-calibrated charge pump is used to suppress spur, and a detect-boosting phase frequency detector is adopted to shorten settling time. With a 200 kHz loop bandwidth, lowest measured phase noise is -106 dBc/Hz at a 10 kHz offset and -131 dBc/Hz at a 1 MHz offset. Fabricated in the TSMC 0.18 μm CMOS process, the synthesizer occupies a chip area of 1.2 mm2, consumes only 15 mW from the 1.8 V power supply, and settles within 13.2 μs. The synthesizer is optimized for the WIA applications, but can also be used for other short-range wireless communications, such as 433, 868, 916 MHz ISM band applications.

  20. Fludarabine-based reduced intensity conditioning transplants have a higher incidence of cytomegalovirus reactivation compared with myeloablative transplants.

    Science.gov (United States)

    George, B; Kerridge, I; Gilroy, N; Huang, G; Hertzberg, M; Gottlieb, D; Bradstock, K

    2010-05-01

    Two hundred and ten adult CMV seropositive patients undergoing myeloablative conditioning (MAC) [n=127] or reduced intensity conditioning (RIC) [n=83] transplants (HCT) were serially monitored for CMV reactivation and disease, using a qualitative polymerase chain reaction (PCR) followed by quantitation with pp65 antigen or quantitative PCR. CMV reactivation occurred in 53 RIC (63.9%) and 61 MAC (48%; P=0.03) transplants at a median of 47 days (range: 24-1977). Risk factors identified included acute GVHD (P=0.001), RIC regimen (P=0.03), unrelated donor (P=0.02), use of anti-thymocyte globulin/alemtuzumb (P=0.02) and use of bone marrow in MAC transplants (P=0.011). On multivariate analysis, RIC transplants and acute GVHD remained independent predictors. Treatment with antiviral drugs resulted in CMV negativity rates of 86.8% in MAC and 88.6% in RIC transplants. CMV disease occurred in 10.8% of RIC and 4.7% of MAC transplants (P=0.15). At a median follow-up of 26 months (range: 3-88), 48.1% of RIC and 50.3% of MAC transplants are alive. The higher incidence of CMV reactivation among RIC transplants suggests the need for novel prophylactic or pre-emptive strategies in this high-risk group of patients.

  1. Zoonotic pathogens species%当今人兽共患病病原体分类

    Institute of Scientific and Technical Information of China (English)

    于恩庶; 黄丰; 潘亮; 王晓欢

    2006-01-01

    根据《Risk factors for human disease emergence》(Louise H.Taylor,2001)和《Host range and emerging and reemerging pathogens》(Mark E.J Woolhouse,2005)两文献所提供的868种人兽共患病病原体,我们以此为基础,利用我们现有的资料进行补充。例如:将原有埃立克体由5种增至10种;原只1种羊布鲁氏菌,现增加了牛布鲁氏菌,猪布鲁氏菌和犬布鲁氏菌;还将SARS和Henipavirus等列入。由于受条件和时间限制,难免出现差错。还有一些来不及列入,今后将继续补充和修改。

  2. In Silico Screening Identifies a Novel Potential PARP1 Inhibitor Targeting Synthetic Lethality in Cancer Treatment

    Directory of Open Access Journals (Sweden)

    Jian Li

    2016-02-01

    Full Text Available Synthetic lethality describes situations in which defects in two different genes or pathways together result in cell death. This concept has been applied to drug development for cancer treatment, as represented by Poly (ADP-ribose polymerase (PARPs inhibitors. In the current study, we performed a computational screening to discover new PARP inhibitors. Among the 11,247 compounds analyzed, one natural product, ZINC67913374, stood out by its superior performance in the simulation analyses. Compared with the FDA approved PARP1 inhibitor, olaparib, our results demonstrated that the ZINC67913374 compound achieved a better grid score (−86.8 and amber score (−51.42. Molecular dynamics simulations suggested that the PARP1-ZINC67913374 complex was more stable than olaparib. The binding free energy for ZINC67913374 was −177.28 kJ/mol while that of olaparib was −159.16 kJ/mol. These results indicated ZINC67913374 bound to PARP1 with a higher affinity, which suggest ZINC67913374 has promising potential for cancer drug development.

  3. Coverage of cervical cancer screening in Catalonia for the period 2008-2011 among immigrants and Spanish-born women.

    Directory of Open Access Journals (Sweden)

    Vanesa eRodriguez-Sales

    2013-12-01

    Full Text Available Background: The Public Health system in Catalonia, Spain provides a free of charge opportunistic cervical cancer screening. In June 2006 a revised recommendations for cervical cancer screening was introduced to increase coverage and to promote a three-year interval between screening tests. Aim: This study examines cervical cancer screening coverage and prevalence of cytology abnormalities in Catalonia by immigration status.Methods: The study analyses the cytologies registered among women aged 25-65 that have been attended at the Primary Health Centers (PHC for any reason (n=1,242,105 during 2008-11. Coverage was estimated from Governmental data base Information System Primary Care (SISAP that includes 77% of PHC. The database is anonymous, and includes information on age, country of birth, diagnostic center and cytology results Results: During the period 2008-2011, 758,690 smears were performed in a total of 595,868 women over 14 years, of whom 18.3% were immigrants. Cytology coverage was higher among immigrant women compared to Spanish born (51.2% and 39% respectively. Immigrant women also had a higher prevalence of abnormal Paps compared to the Spanish population, 4.9% and 3.3% respectively.Conclusion: Immigrant women in Catalonia have a good access to the Public Health Services and to cervical cancer screening facilities. The higher prevalence of abnormal cytologies in immigrant women compared to native women indicates the relevance to prioritize cervical cancer screening activities on a regular base in new comers.

  4. Analysis of Passive RF-DC Power Rectification and Harvesting Wireless RF Energy for Micro-watt Sensors

    Directory of Open Access Journals (Sweden)

    Antwi Nimo

    2015-04-01

    Full Text Available In this paper, analytical modeling of passive rectifying circuits and the harvesting of electromagnetic (EM power from intentionally generated as well as from ubiquitous sources are presented. The presented model is based on the linearization of rectifying circuits. The model provides an accurate method of determining the output characteristics of rectifying circuits. The model was verified with Advance Design System (ADS Harmonic balance (HB simulations and measurements. The results from the presented model were in agreement with simulations and measurements. Consequently design considerations and trade-off of radio frequency (RF harvesters are discussed. To verify the exploitation of ambient RF power sources for operation of sensors, a dual-band antenna with a size of ~λ/4 at 900MHz and a passive dual-band rectifier that is able to power a commercial Thermo-Hygrometer requiring ~1.3V and 0.5MΩ from a global system for mobile communications (GSM base station is demonstrated. The RF power delivered by the receiving dual-band antenna at a distance of about 110 m from the GSM base station ranges from -27 dBm to -50 dBm from the various GSM frequency bands. Additionally, wireless range measurements of the RF harvesters in the industrial, scientific and medical (ISM band 868MHz is presented at indoor conditions.

  5. Comparison of adsorption behavior of PCDD/Fs on carbon nanotubes and activated carbons in a bench-scale dioxin generating system.

    Science.gov (United States)

    Zhou, Xujian; Li, Xiaodong; Xu, Shuaixi; Zhao, Xiyuan; Ni, Mingjiang; Cen, Kefa

    2015-07-01

    Porous carbon-based materials are commonly used to remove various organic and inorganic pollutants from gaseous and liquid effluents and products. In this study, the adsorption of dioxins on both activated carbons and multi-walled carbon nanotube was internally compared, via series of bench scale experiments. A laboratory-scale dioxin generator was applied to generate PCDD/Fs with constant concentration (8.3 ng I-TEQ/Nm(3)). The results confirm that high-chlorinated congeners are more easily adsorbed on both activated carbons and carbon nanotubes than low-chlorinated congeners. Carbon nanotubes also achieved higher adsorption efficiency than activated carbons even though they have smaller BET-surface. Carbon nanotubes reached the total removal efficiency over 86.8 % to be compared with removal efficiencies of only 70.0 and 54.2 % for the two other activated carbons tested. In addition, because of different adsorption mechanisms, the removal efficiencies of carbon nanotubes dropped more slowly with time than was the case for activated carbons. It could be attributed to the abundant mesopores distributed in the surface of carbon nanotubes. They enhanced the pore filled process of dioxin molecules during adsorption. In addition, strong interactions between the two benzene rings of dioxin molecules and the hexagonal arrays of carbon atoms in the surface make carbon nanotubes have bigger adsorption capacity.

  6. Epidemiology of road traffic mortality and injuries in Yazd, Iran during 2003-2008

    Institute of Scientific and Technical Information of China (English)

    Hossien Fallahzadeh; Atefeh Dehgani

    2011-01-01

    Objective: Road traffic crashes (RTCs) are considered to be the second highest cause of mortality in Iran. The purpose of this study was to describe the morbidity and mortality of RTC during 2003-2008.Methods: Data were got from national health sources of Iran. These data included population, the number of RTCs,consequent fatalities, cause and place of death from 2003 to 2008.Results: RTC incidence rate increased from 868.5 per 100 000 population in the year 2003 to 1 643.6 in 2008. A total of 2 565 deaths from RTC were recorded in Yazd from 2003 to 2008. RTC mortality rate increased from 46.1 per 100 000 population in 2003 to 46.9 in 2006, then declined to 38.8 in 2008. During this time period, overall traffic injury incidence per 100 000 population increased from 368.8 in 2003 to 647.9 in 2006, then declined to 527.9 in 2008. Head injuries were the most common cause of road traffic-related mortality from 2003 to 2008. Following road traffic accidents, most of the deaths occurred before arriving hospital.Conclusions: Road traffic crash-related mortality and morbidity in Yazd in the recent six years are increased, but decreased in the last two years. This decline is most probably the result of a variety of interventions, including laws,police enforcement, improvements in traffic and transport,health care resources and media and public education.

  7. Convective cooling of photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Hodge, E.; Gibbons, C. [Energy Engineering Group, Mechanical Engineering Department, Cork Institute of Technology, Bishopstown, Cork (Ireland)

    2004-07-01

    Most solar cells presently on the market are based on silicon wafers, the so-called first generation technology. As this technology has matured costs have become increasingly dominated by material costs. In the last ten years, continuous work has brought the efficiency of standard cells to the 25% region. A switch to second generation or thin film technology cells now seems imminent. Thin film technology eliminates the silicon wafer and offer the prospect of reducing material and manufacturing costs, but they exhibit lower efficiencies of around 10% for a commercial device. Third generation or tandem cells are currently at a 'proof of concept' research level, with a theoretical conversion rate of 86.8% being asserted Whatever the material construction and manufacturing method of cells, the thermal effect of overheating will prevail in the semiconductor and it is accepted that a lowered temperature will bring about an increase in conversion efficiency. The aim of this project is to improve the efficiency of PV electrical output, by convectively cooling the cells through perforations in them. As the cells heat up they lose efficiency. As the panel heats up a loss in efficiency of 0.5% per C increase in temperature has been recorded. (orig.)

  8. Evaluation of anti-inflammatory activity and fast UHPLC-DAD-IT-TOF profiling of polyphenolic compounds extracted from green lettuce (Lactuca sativa L.; var. Maravilla de Verano).

    Science.gov (United States)

    Pepe, Giacomo; Sommella, Eduardo; Manfra, Michele; De Nisco, Mauro; Tenore, Gian Carlo; Scopa, Antonio; Sofo, Adriano; Marzocco, Stefania; Adesso, Simona; Novellino, Tiziana; Campiglia, Pietro

    2015-01-15

    Fresh cut vegetables represent a widely consumed food worldwide. Among these, lettuce (Lactuca sativa L.) is one of the most popular on the market. The growing interest for this "healthy" food is related to the content of bioactive compounds, especially polyphenols, that show many beneficial effects. In this study, we report the anti-inflammatory and antioxidant potential of polyphenols extracted from lettuce (var. Maravilla de Verano), in J774A.1 macrophages stimulated with Escherichia coli lipopolysaccharide (LPS). Lettuce extract significantly decreased reactive oxygen species, nitric oxide release, inducible nitric oxide synthase and cycloxygenase-2 expression. A detailed quali/quantitative profiling of the polyphenolic content was carried out, obtaining fast separation (10 min), good retention time and peak area repeatability, (RSD% 0.80 and 8.68, respectively) as well as linearity (R(2)⩾ 0.999) and mass accuracy (⩽ 5 ppm). Our results show the importance in the diet of this cheap and popular food for his healthy properties.

  9. Diagnostic value of pleural fluid adenosine deaminase activity in tuberculosis pleurisy

    Directory of Open Access Journals (Sweden)

    Abbas ali Niazi

    2009-09-01

    Full Text Available Background: Diagnosis of tuberculosis pleurisies is difficult because of its nonspecific clinical presentation and insufficient traditional diagnostic methods. We investigated the use of adenosine deaminase (ADA activity in tuberculosis pleurisies. Methods: A number of 85 patients were analyzed with exudative pleural effusions. Using the ROC curve, we determined the optimal cutoff for TB pleurisy. Results: A number of 58 exudative samples were nontuberculous (non-TB and 27 were tuberculosis (TB. There was statistically significant difference (p<0.0001 between the means of pleural fluid ADA levels among the TB and non-TB populations. The prevalence of TB pleurisy in the studied population was 31%. Using the cutoff point equal to 35 for diagnosing TB effusions the sensitivity and specificity 70.3% and 91.3%, respectively. The positive predictive value (PPV was 79.1% and the negative predictive value (NPV was 86.8%. A pleural fluid ADA value <19 IU/L suggests that a tuberculosis effusion is highly unlikely. Conclusion: Pleural fluid total ADA assay is a sensitive and specific test suitable for rapid diagnosis of TB pleurisy.

  10. Adaptação da “The Resilience Scale” para a população adulta portuguesa

    Directory of Open Access Journals (Sweden)

    Cláudia Alexandra Ferreira de Carvalho Ng Deep

    2012-06-01

    Full Text Available Este artigo descreve a adaptação da “The Resilience Scale” para portugueses adultos. Procedeu-se à retradução e validação psicométrica. Fez-se pré-teste e reteste. Obteve-se equivalência linguística/conceptual e validação psicométrica com alpha de Cronbach 0,868 para 23 itens, sugerindo consistência interna. A análise fatorial agrupou 23 variáveis em 4 fatores: I - Perseverança; II - Sentido de vida; III - Serenidade; IV - Autossuficiência e autoconfiança, com valores alpha de Cronbach satisfatórios para cada fator. Verificou-se sensibilidade dos itens através do coeficiente de assimetria e achatamento e comprovou-se a estabilidade temporal. A escala revela boas características psicométricas aferindo níveis de resiliência nesta população.

  11. Antioxidant and α-amylase inhibition activities of phenolic compounds in the extracts of Indian honey

    Institute of Scientific and Technical Information of China (English)

    Subashini Devarajan; Subhashree Venugopal

    2012-01-01

    AIM:To evaluate the antioxidant and α-amylase inhibition potential of phenolic compounds in the extracts of Indian honey.METHODS:Phenolic compounds were extracted from Indian honey through column chromatography.The antioxidant potential of extracted phenolic compounds was measured by two different biochemical assays:ferric reducing antioxidant power (FRAP)assay and scavenging activity on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals.Moreover,α-amylase inhibition assay of phenolic compounds of honey was also evaluated.RESULTS:The scavenging inhibition rate varied from 86.8% to 78.6% from the highest (6mg·mL-1) to the lowest (1.5 mg·mL-1) concentration,whereas,reducing power assay varied from 0.89 Abs to 0.19 Abs from the highest to the lowest concentration.Butylated hydroxytoluene (BHT) was used as reference compound for antioxidant assays.α-amylase inhibition assay is reported from the phenolic honey extracts for the first time.The inhibition rate for α-amylase varied from 88.8% to 30.5% from the highest (20 μg·mL-1) to the lowest concentration (4.μg·mL-1).CONCLUSION:Honey phenolic extract possessed antioxidant and α-amylase inhibition activity,thus increasing its potential therapeutic property.

  12. Within-Host and Population Transmission of blaOXA-48 in K. pneumoniae and E. coli.

    Science.gov (United States)

    Haverkate, Manon R; Dautzenberg, Mirjam J D; Ossewaarde, Tjaco J M; van der Zee, Anneke; den Hollander, Jan G; Troelstra, Annet; Bonten, Marc J M; Bootsma, Martin C J

    2015-01-01

    During a large hospital outbreak of OXA-48 producing bacteria, most K. pneumoniaeOXA-48 isolates were phenotypically resistant to meropenem or imipenem, whereas most E. coliOXA-48 isolates were phenotypically susceptible to these antibiotics. In the absence of molecular gene-detection E. coliOXA-48 could remain undetected, facilitating cross-transmission and horizontal gene transfer of blaOXA-48. Based on 868 longitudinal molecular microbiological screening results from patients carrying K. pneumoniaeOXA-48 (n = 24), E. coliOXA-48 (n = 17), or both (n = 40) and mathematical modelling we determined mean durations of colonisation (278 and 225 days for K. pneumoniaeOXA-48 and E. coliOXA-48, respectively), and horizontal gene transfer rates (0.0091/day from K. pneumoniae to E. coli and 0.0015/day vice versa). Based on these findings the maximum effect of horizontal gene transfer of blaOXA-48 originating from E. coliOXA-48 on the basic reproduction number (R0) is 1.9%, and it is, therefore, unlikely that phenotypically susceptible E. coliOXA-48 will contribute significantly to the spread of blaOXA-48.

  13. Development of a Specific Latex Agglutination Test to Detect Antibodies of Enterovirus 71.

    Science.gov (United States)

    Qin, Bo; Zhang, Jianhua; Xie, Wenhao; Liu, Xuehong; He, Tingting; Chen, Jinkun; Dong, Xuejun

    2015-10-01

    A latex agglutination test (LAT) was developed for the rapid detection of antibodies against the VP1 or VP1 proteins of Enterovirus 71 (EV71). The proteins of interest including prokaryotically expressed VP1 and two strains of anti-VP1 monoclonal antibody (McAb) against EV71 were covalently linked to carboxylated latex using ethyl-dimethyl-amino-propyl carbodiimide (EDC) to prepare sensitized latex beads. LAT was evaluated by an enzyme-linked immunosorbent assay (ELISA) as a reference test. The VP1-LAT showed a sensitivity of 87.0%, specificity of 88.9%, and an agreement ratio of 90.0% in detecting VP1 in 100 serum samples from experimentally infected mice, whereas these values were 86.8, 96.7, and 93.3%, respectively, for 608 clinical human serum samples. The VP1-LAT has advantages over other assays in terms of low cost, rapidity, chemical stability, high sensitivity, repeatability, and specificity. The LAT established in the present study is a rapid and simple test suitable for field monitoring of antibodies against VP1-EV71.

  14. Back propagation artificial neural network for community Alzheimer's disease screening in China.

    Science.gov (United States)

    Tang, Jun; Wu, Lei; Huang, Helang; Feng, Jiang; Yuan, Yefeng; Zhou, Yueping; Huang, Peng; Xu, Yan; Yu, Chao

    2013-01-25

    Alzheimer's disease patients diagnosed with the Chinese Classification of Mental Disorders diagnostic criteria were selected from the community through on-site sampling. Levels of macro and trace elements were measured in blood samples using an atomic absorption method, and neurotransmitters were measured using a radioimmunoassay method. SPSS 13.0 was used to establish a database, and a back propagation artificial neural network for Alzheimer's disease prediction was simulated using Clementine 12.0 software. With scores of activities of daily living, creatinine, 5-hydroxytryptamine, age, dopamine and aluminum as input variables, the results revealed that the area under the curve in our back propagation artificial neural network was 0.929 (95% confidence interval: 0.868-0.968), sensitivity was 90.00%, specificity was 95.00%, and accuracy was 92.50%. The findings indicated that the results of back propagation artificial neural network established based on the above six variables were satisfactory for screening and diagnosis of Alzheimer's disease in patients selected from the community.

  15. Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol.

    Science.gov (United States)

    Farris, Patricia; Zeichner, Joshua; Berson, Diane

    2016-07-01

    Consumers are increasingly interested in over-the-counter skin care products that can improve the appearance of photodamaged and aging skin. This 10-week, open-label, single- center study enrolled 25 subjects with mild to moderate hyperpigmentation and other clinical stigmata of cutaneous aging including fine lines, sallowness, lack of clarity, and wrinkling. Their mean age was 53.4±7.7 years. The test product contained retinol 0.5% in combination with niacinamide 4.4%, resveratrol 1%, and hexylresorcinol 1.1% in a moisturizing base. Subjects were provided a skin care regimen including a cleanser, hydrating serum, moisturizer, and an SPF 30 sunscreen for daily use. The test product was applied only at night. The use of this skin brightening/anti-aging cosmeceutical was found to provide statistically significant improvements in all efficacy endpoints by study end. Fine lines, radiance, and smoothness were significantly improved as early as week 2 (P The results of this open-label clinical study suggest that a topical cream containing retinol 0.5% in combination with niacinamide, resveratrol, and hexylresorcinol is efficacious and tolerable for skin brightening/anti-aging when used with a complementary skin care regimen including SPF 30 sun protection. J Drugs Dermatol. 2016;15(7):863-868.

  16. Saudi Moumouvirus, the First Group B Mimivirus Isolated from Asia

    Science.gov (United States)

    Bajrai, Leena H.; de Assis, Felipe L.; Azhar, Esam I.; Jardot, Priscilla; Robert, Catherine; Abrahão, Jônatas; Raoult, Didier; La Scola, Bernard

    2016-01-01

    The number of novel giant viruses identified and characterized from the recently proposed order Megavirales has increased in recent years and new questions have been raised regarding viral diversity and evolution. Here, we describe the isolation and characterization of Saudi moumouvirus (SDMV), a new giant virus belonging to Mimivirus lineage B, isolated from a sewage sample taken from the King Abdulaziz University hospital in Jeddah, Saudi Arabia. SDMV presented 500 nm icosahedral particles with a 1,046,087 bp genome, which is larger than moumouvirus-like genomes which have been described in the past. The SDMV genome was predicted to encode 868 ORFs, ranging in size from 54 to 2,914 amino acids, with a mean size of 349 aa. Furthermore, this genome was predicted to encode 40 new genes (ORFans) without similarity with other sequences (ORFan L850 transcript was detected by qPCR in infected amoeba), in addition to 42 hypothetical proteins (pseudo-ORFs) with less than 100 aa, which matched other sequences in the NCBI nr database. Phylogenetic analysis showed that SDMV clustered together with mimiviruses from lineage B, including moumouvirus-like strains. It is, therefore, the third Mimivirus to be isolated in Asia and the first of group B. PMID:28066355

  17. 绍兴市皋埠镇农民健康体检脂肪肝患病率及相关因素分析

    Institute of Scientific and Technical Information of China (English)

    王莲芳

    2011-01-01

    目的 了解绍兴市农民非洒精性脂肪肝肝病(NAFLD)的患病状况,并分析相关因素.方法 收集2010年绍兴市皋埠镇进行健康体检的农民2 648例,根据检验结果及肝脏B超结果分为2组,其中NAFLD组868例,非NAFLD组1 780例,比较分析NAFLD的相关因素.结果 NAFLD总体患病率32.78%,其中男性占34.68%,女性占65.32%,女性患病率明显高于男性.NAFLD组中肥胖、血脂异常、高血压及糖代谢异常的检出率均明显高于非NAFLD组(均P<0.01).NAFLD组体质量指数(BMI)、甘油三酯、胆固醇、空腹血糖、收缩压及舒张压均显著高于非NAFLD组(均P<0.01).结论 肥胖、高血压、高血糖、高血脂与NAFLD密切相关.

  18. Difference of Phytic Acid Content and its Relation to Four Protein Composition Contents in Grains of Twenty-nine japonica Rice Varieties from Jiangsu and Zhejiang Provinces, China

    Institute of Scientific and Technical Information of China (English)

    WU Wei; CHENG Fang-min; LIU Zheng-hui; WEI Ke-su

    2007-01-01

    Twenty-nine japonica rice varieties collected from Jiangsu and Zhejiang Provinces, China were planted in Hangzhou,China, to investigate the phytic acid content in brown rice and its frequency distribution as well as the correlation among the contents of phytic acid, total protein and four protein compositions in brown rice. The phytic acid content in brown rice ranged from 0.699% to 1.034%, with a mean of 0.868% for the 29 tested rice varieties. Xiushui series rice varieties generally exhibited lower phytic acid level than Wuyujing and Huai series rice varieties. A rough normal distribution, with a mean of 8.722%, was observed for the total protein contents in the tested varieties. Of the four protein compositions, the glutelin, globulin and albumin contents had larger coefficient of variation than the prolamin content, although the difference in prolamin content was genotype-dependent. No significant correlation was found between the phytic acid and four protein composition contents, whereas the total protein content was significantly and positively related to the glutelin content in brown rice.

  19. Convergent validity between SF-36 and WHOQOL-BREF in older adults

    Directory of Open Access Journals (Sweden)

    Paula Costa Castro

    2014-02-01

    Full Text Available OBJECTIVE : To compare the reliability and convergent validity of instruments assessing quality of life in Brazilian older adults. METHODS : Cross-sectional study of 278 literate, community-dwelling older adults attending a municipal university for the elderly in Sao Carlos, SP, Southeastern Brazil between 2006 and 2008. The Brazilian versions of the SF-36 and WHOQOL-BREF instruments to assess quality of life were compared. Cronbach’s alpha coefficient was used to estimate reliability and Pearson’s correlation for comparison between the two scales. RESULTS : Most of participants were women (87.8% with a mean age of 63.83±7.22 years. Both scales showed an acceptable internal consistency – WHOQOL-BREF Cronbach’s alpha was 0.832 and SF-36 was 0.868. There was a weak (r ≤ 0.6 correlation between the related fields in the two questionnaires. CONCLUSIONS : The SF-36 and WHOQOL-BREF are reliable instruments for clinical and research uses in Brazilian older women. To select one, researchers should consider which aspects of quality of life they aim to capture because of weak convergent validity signs. This study’s results indicate that WHOQOL-BREF may be more relevant to evaluate changes in the quality of life of older women because it prioritizes responses to the aging process and avoids focusing on impairment.

  20. Integral PVA-PES Composite Membranes by Surface Segregation Method for Pervaporation Dehydration of Ethanol

    Institute of Scientific and Technical Information of China (English)

    吴洪; 李宪实; 聂明成; 李犇; 姜忠义

    2011-01-01

    A facile surface segregation method was utilized to fabricate poly(vinyl alcohol)-polyethersulfone (PVA-PES) composite membranes. PVA and PES were first dissolved in dimethyl sulfoxide (DMSO), then casted on a glass plate and immersed in a coagulation bath. During the phase inversion process in coagulation bath, PVA spontaneously segregated to the polymer solution/coagulation bath interface. The enriched PVA on the surface was further crosslinked by glutaraldehyde. Scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and energy dispersive spectrometer (EDS) confirmed the integral and asymmetric membrane structure with a dense PVA-enriched surface and a porous PES-enriched support, as well as the surface enrichment of PVA. The coverage fraction of the membrane surtace by PVA reacned up to 86.8% when me PVA content m me membrane recipe was 16.7% (by mass). The water contact angle decreased with the increase of PVA content. The effect of coagulation bath type on membrane structure was analyzed. The membrane pervaporation performance was evaluated by varying the PVA content, the annealing temperature, feed concentration and operation temperature. The membrane exhibited a fairly good ethanol dehydration capacity and long-term operational stability.

  1. Elemental analysis of limestone samples from Ewekoro limestone deposit in southwest Nigeria

    Science.gov (United States)

    Obiajunwa, E. I.; Nwachukwu, J. I.

    2000-10-01

    Limestone samples of different colours from Ewekoro limestone deposit in Ogun State, Nigeria were subjected to elemental analysis by proton-induced X-ray emission (PIXE) and proton-induced gamma-ray emission (PIGME) techniques. The irradiation was by 2.5 MeV proton beams from the ion beam analysis (IBA) facility of the 3 MV Van de Graaff accelerator at the Australian Nuclear Science and Technology Organisation (ANSTO), Lucas Heights. Elemental composition and concentrations of 22 major, minor and trace elements were determined. The NIST geological standard, NBS278, was analysed for quality assurance. The concentrations of the major elements (Ca, Fe, K and Al) are similar in the samples while the other major elements differed. Calcium accounts for about 38%, giving 86.8% CaCO 3 content in the limestones. The major elements (Al, Ca, Fe, Si, S and K), present in the limestones, were also found to be enriched in airborne particulate matter studied by earlier workers, thus confirming cement dust as the major contributor to the particulate matter within and around cement factories.

  2. Removing and recovering of uranium from the acid mine waters by using ion exchange resin; Remocao e recuperacao de uranio de aguas acidas de mina por resina de troca ionica

    Energy Technology Data Exchange (ETDEWEB)

    Nascimento, Marcos Roberto Lopes do

    1998-07-01

    Ion exchange using resins is one of the few processes capable of reducing ionic contaminants in effluents to very low levels. In this study the process was used to remove and recovery uranium from acid mine waters at Pocos de Caldas-MG Uranium Mining and Milling Plant. The local mineralogical features, allied to the biogeochemical phenomena, owing to presence of pyrite in the rock piles, moreover another factors, resulting acid drainage with several pollutants, including uranium ranging from 6 to 14 mg/l, as sulfate complex, that can be removed by anionic exchanger. The iron interference is eliminated by lime pretreatment of water, increasing pH from 2.6 to 3.3-3.8 to precipitate this cation, without changing the uranium amount. Eight anionic resins were tested, based on the uranium loading, in sorption studies. Retention time, and pH influence was verified for the exchanger chose. With breakthrough of 1 mg U/L and 10 mg U/l in the feed solution, the uranium decontamination level was 94%. Typical values of loading resin were 20-30 g U/l and 70-90 g SO{sub 4}/l. Uranium elution was done with Na Cl solution. Retention time, saline, and acid concentration were the parameters studied. The concentrate, obtained from the eluate by ammonia precipitation, presented uranium (86,8% as U{sub 3} O{sub 8}) and impurities within commercial specifications. (author)

  3. Factors affecting the prevalence of obesity among primary school students

    Directory of Open Access Journals (Sweden)

    Meltem Kürtüncü

    2014-09-01

    Full Text Available Objective: The aim of this descriptive study was to investigate the risk factors affecting obesity in students in the 6-15 years old age group. There were 868 students registered at Bahçelievler Elementary School in Zonguldak and were present for face-to-face meetings on the days the research data was collected. Data was collected using demographic questionary forms and weight-length measurements from March to April in 2010. Results: Difference is found to be statistically meaningful with respect to the relationship between obesity of children and their age, gender, number of siblings, fathers’ jobs, education level of their mothers, fast food consumption and family history of obesity (p<0.05. Conclusions: The study concludes that there are certain ciriteria related to the development of obesity during a specific period of childhood and that taking certain precautions are effective in preventing the development of obesity. Keywords: Body Mass Index; Children; Obesity; Prevalence; Risk Factors; Turkey.

  4. Spatiotemporal variations of extreme low temperature for emergency transport: a nationwide observational study

    Science.gov (United States)

    Onozuka, Daisuke; Hagihara, Akihito

    2016-12-01

    Although recent studies have investigated the effect of extreme heat on emergency transport, few have investigated the spatiotemporal variations of extreme low temperature for emergency transport on a national scale. Data pertaining to emergency ambulance transport and weather variation in the 47 prefectures of Japan between 2007 and 2010 were obtained. Nonlinear and delayed relationships between temperature and morbidity were assessed using a two-stage analysis. First, a Poisson regression analysis allowing for overdispersion in a distributed lag nonlinear model was used to estimate the prefecture-specific effects of temperature on morbidity. Second, a multivariate meta-analysis was applied to pool estimates on a national level. Of 15,868,086 emergency transports over the study period, 5,375,621 emergency transports were reported during the winter months (November through February). The overall cumulative relative risk (RR) at the first percentile vs. the minimum morbidity percentile was 1.24 (95 % CI = 1.15-1.34) for all causes, 1.50 (95 % CI = 1.30-1.74) for cardiovascular diseases, and 1.59 (95 % CI = 1.33-1.89) for respiratory diseases. There were differences in the temporal variations between extreme low temperature and respiratory disease morbidity. Spatial variation between prefectures was observed for all causes (Cochran Q test, p social and environmental factors, which can be responsible for spatial heterogeneity between prefectures.

  5. Porous carbon with a large surface area and an ultrahigh carbon purity via templating carbonization coupling with KOH activation as excellent supercapacitor electrode materials

    Science.gov (United States)

    Sun, Fei; Gao, Jihui; Liu, Xin; Pi, Xinxin; Yang, Yuqi; Wu, Shaohua

    2016-11-01

    Large surface area and good structural stability, for porous carbons, are two crucial requirements to enable the constructed supercapacitors with high capacitance and long cycling lifespan. Herein, we successfully prepare porous carbon with a large surface area (3175 m2 g-1) and an ultrahigh carbon purity (carbon atom ratio of 98.25%) via templating carbonization coupling with KOH activation. As-synthesized MTC-KOH exhibits excellent performances as supercapacitor electrode materials in terms of high specific capacitance and ultrahigh cycling stability. In a three electrode system, MTC-KOH delivers a high capacitance of 275 F g-1 at 0.5 A g-1 and still 120 F g-1 at a high rate of 30 A g-1. There is almost no capacitance decay even after 10,000 cycles, demonstrating outstanding cycling stability. In comparison, pre-activated MTC with a hierarchical pore structure shows a better rate capability than microporous MTC-KOH. Moreover, the constructed symmetric supercapacitor using MTC-KOH can achieve high energy densities of 8.68 Wh kg-1 and 4.03 Wh kg-1 with the corresponding power densities of 108 W kg-1 and 6.49 kW kg-1, respectively. Our work provides a simple design strategy to prepare highly porous carbons with high carbon purity for supercapacitors application.

  6. Nickel(II) complexes of N2S2 donor set ligand and halide/pseudohalides: Synthesis, crystal structure, DNA and bovine/human serum albumin interaction

    Indian Academy of Sciences (India)

    Animesh Patra; Biplab Mondal; Buddhadeb Sen; Ennio Zangrando; Pabitra Chattopadhyay

    2015-11-01

    A series of neutral hexacoordinated nickel(II) complexes of formula [NiII (L)X2] (where L = 3,4-bis(2-pyridylmethylthio)toluene with tetradentate N2S2 donor set and X = chloride (1), azide (2), cyanate (3) and isothiocyanate anion (4)) have been synthesized and isolated in pure form. The complexes were characterized by physicochemical and spectroscopic methods along with detailed structural characterization of 1,2 and 3 by single crystal X-ray diffraction analyses. The structural study showed that the nickel(II) ion has a distorted octahedral geometry being chelated by the tetradentate N2S2 ligand and bound to cis- located choride or pseudohalide anions. In dimethylformamide solution the complexes showed quasi-reversible NiII/NiIII redox couples in cyclic voltammograms with E1/2 values of +0.723, +0.749, +0.768 and +0.868 V for 1, 2, 3 and 4, respectively. The study of interaction of the complexes with calf thymus DNA, bovine serum albumin (BSA) and human serum albumin (HSA) using spectroscopic and physicochemical tools clearly indicates that the complexes interact with DNA via groove binding mode.

  7. Need for a global obstetric fistula training strategy.

    Science.gov (United States)

    Rushwan, Hamid; Khaddaj, Sinan; Knight, Louise; Scott, Rachel

    2012-10-01

    Obstetric fistula is a complication of childbirth that often follows obstructed labor and is almost exclusive to low-resource countries. The original Global Burden of Disease Study (GBD 1990 Study) reported an incidence of 8.68 per 100000 and a prevalence of 51.35 per 100,000 for women aged 15-44 years in low-resource regions. The most cited global prevalence estimate is 2 million women. Although the global burden of obstetric fistula remains unclear, the number of women suffering from the condition is increasing, while surgical treatment remains limited. There are few experienced fistula surgeons and past surgical training approaches have been inconsistent. The Global Competency-Based Fistula Surgery Training Manual developed by FIGO and partners contains a set curriculum and, to ensure its implementation, a global strategy and training program have been developed. This paper describes key elements of the training program and its implementation. The anticipated impact of the training program is a reduction in global morbidity caused by obstetric fistula.

  8. Study on Antioxidant Activity of Extracts from Ipomea Pes-caprae (Linn.) Sweet%海滩植物厚藤(Ipomoea Pes-caprae)抗氧化活性研究

    Institute of Scientific and Technical Information of China (English)

    刘平怀; 陈德力; 汪春牛; 许琼情; 刘洋洋

    2010-01-01

    采用加速溶剂萃取技术(ASE)快速制备厚藤活性提取物,并以DPPH法对厚藤茎叶不同溶剂提取物抗氧化活性进行评价.抗坏血酸抗氧化能力>乙酸乙酯提取物抗氧化能力>乙醇提取物抗氧化能力>甲醇提取物抗氧化能力>石油醚提取物抗氧化能力,其IC50值分别为0.203 4、0.836 2、0.868 8、1.867 5、6.628 3 g/L.结果显示,厚藤茎叶提取物具有一定的抗氧化活性,且以乙酸乙酯为提取溶剂时,效果最佳.

  9. Simultaneous Determination of Residue of Captan and Flopet in Fruits by High performance Liquid Chromatography%高效液相色谱法同时测定水果中克菌丹和灭菌丹残留量

    Institute of Scientific and Technical Information of China (English)

    邵永源; 修长泽; 吴会进

    2007-01-01

    [目的]采用高效液相色谱法,同时测定水果中克菌丹和灭菌丹残留量.[方法]采用Florisil固相萃取柱净化样品,对样品进行预处理,并对色谱条件进行优化.[结果]同时测定克菌丹和灭菌丹,波长选择为210nm.克菌丹保留时间为10.7 min,检出限为0.75 mg/L,平均回收率为86.8%~106.0%.灭菌丹保留时间为17.6 min,检出限为0.60mg/L,平均回收率为101.6%~105.8%.[结论]采用Florisil固相萃取柱作为固相萃取的净化方法,建立了固相萃取-高效液相色谱法同时测定水果中克菌丹和灭菌丹残留量的分析方法.该方法简单,在实际工作中应用效果好.

  10. An extended finite element formulation for modeling the response of polycrystalline materials to shock loading

    Science.gov (United States)

    Robbins, Joshua; Voth, Thomas

    2007-06-01

    The eXtended Finite Element Method (X-FEM) is a finite element based discretization technique developed originally to model dynamic crack propagation [1]. Since that time the method has been used for modeling physics ranging from static mesoscale material failure to dendrite growth. Here we adapt the recent advances of Benson et al. [2] and Belytchko et al. [3] to model shock loading of polycrystalline material. Through several demonstration problems we evaluate the method for modeling the shock response of polycrystalline materials at the mesoscale. Specifically, we use the X-FEM to model grain boundaries. This approach allows us to i) eliminate ad-hoc mixture rules for multi-material elements and ii) avoid explicitly meshing grain boundaries. ([1] N. Moes, J. Dolbow, J and T. Belytschko, 1999,``A finite element method for crack growth without remeshing,'' International Journal for Numerical Methods in Engineering, 46, 131-150. [2] E. Vitali, and D. J. Benson, 2006, ``An extended finite element formulation for contact in multi-material arbitrary Lagrangian-Eulerian calculations,'' International Journal for Numerical Methods in Engineering, 67, 1420-1444. [3] J-H Song, P. M. A. Areias and T. Belytschko, 2006, ``A method for dynamic crack and shear band propagation with phantom nodes,'' International Journal for Numerical Methods in Engineering, 67, 868-893.)

  11. Three sub-Jupiter-mass planets: WASP-69b & WASP-84b transit active K dwarfs and WASP-70Ab transits the evolved primary of a G4+K3 binary

    CERN Document Server

    Anderson, D R; Delrez, L; Doyle, A P; Faedi, F; Fumel, A; Gillon, M; Chew, Y Gómez Maqueo; Hellier, C; Jehin, E; Lendl, M; Maxted, P F L; Pepe, F; Pollacco, D; Queloz, D; Ségransan, D; Skillen, I; Smalley, B; Smith, A M S; Southworth, J; Triaud, A H M J; Turner, O D; Udry, S; West, R G

    2013-01-01

    We report the discovery of the transiting exoplanets WASP-69b, WASP-70Ab and WASP-84b, each of which orbits a bright star (V~10). WASP-69b is a bloated Saturn-mass planet (0.26 M$_{\\rm Jup}$, 1.06 R$_{\\rm Jup}$) in a 3.868-d period around an active mid-K dwarf. We estimate a stellar age of 1 Gyr from both gyrochronological and age-activity relations, though an alternative gyrochronological relation suggests an age of 3 Gyr. ROSAT detected X-rays at a distance of 60$\\pm$27 arcsec from WASP-69. If the star is the source then the planet could be undergoing mass-loss at a rate of ~10$^{12}$ g s$^{-1}$. This is 1-2 orders of magnitude higher than the evaporation rate estimated for HD 209458b and HD 189733b, both of which have exhibited anomalously-large Lyman-{\\alpha} absorption during transit. WASP-70Ab is a sub-Jupiter-mass planet (0.59 M$_{\\rm Jup}$, 1.16R$_{\\rm Jup}$) in a 3.713-d orbit around the primary of a spatially-resolved G4+K3 binary, with a separation of 3.3 arcsec ($\\geq$800 AU). We exploit the binar...

  12. COLOUR, PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF THE SLOVAK ALIBERNET RED WINE SAMPLES

    Directory of Open Access Journals (Sweden)

    Daniel Bajčan

    2015-02-01

    Full Text Available Sixteen Alibernet wine samples, originated from three most important Slovak vineyard regions, were evaluated spectrophotometrically for the content of total polyphenols, content of total anthocyanins, antioxidant activity and wine colour density. The determined total polyphenol contents in observed wines ranged from 2141 to 4274 mg gallic acid per liter (average content was 3057 mg gallic acid/L and total anthocyanin contents ranged from 73.4 to 791.2 mg/L (average content was 403.4 mg/L. Determined values of antioxidant activity were within the interval 54.8 – 86.8% (average value was 74.5% and the values of wine colour density varied between 0.944 and 4.592 (average value was 2.317. The statistical evaluation of the obtained results confirmed only weak linear correlation between total polyphenol content and total anthocyanin content, however strong linear correlations between total anthocyanin content and antioxidant activity, resp. wine colour density were observed. Our results also confirmed very highly significant linear relationship between wine colour density and total polyphenol content, resp. antioxidant activity and between antioxidant activity and total phenolic content.

  13. Quality of life after total vs distal gastrectomy with Roux-en-Y reconstruction: Use of the Postgastrectomy Syndrome Assessment Scale-45

    Science.gov (United States)

    Takahashi, Masazumi; Terashima, Masanori; Kawahira, Hiroshi; Nagai, Eishi; Uenosono, Yoshikazu; Kinami, Shinichi; Nagata, Yasuhiro; Yoshida, Masashi; Aoyagi, Keishiro; Kodera, Yasuhiro; Nakada, Koji

    2017-01-01

    AIM To investigate the detrimental impact of loss of reservoir capacity by comparing total gastrectomy (TGRY) and distal gastrectomy with the same Roux-en-Y (DGRY) reconstruction. The study was conducted using an integrated questionnaire, the Postgastrectomy Syndrome Assessment Scale (PGSAS)-45, recently developed by the Japan Postgastrectomy Syndrome Working Party. METHODS The PGSAS-45 comprises 8 items from the Short Form-8, 15 from the Gastrointestinal Symptom Rating Scale, and 22 newly selected items. Uni- and multivariate analysis was performed on 868 questionnaires completed by patients who underwent either TGRY (n = 393) or DGRY (n = 475) for stage I gastric cancer (52 institutions). Multivariate analysis weighed of six explanatory variables, including the type of gastrectomy (TGRY/DGRY), interval after surgery, age, gender, surgical approach (laparoscopic/open), and whether the celiac branch of the vagus nerve was preserved/divided on the quality of life (QOL). RESULTS The patients who underwent TGRY experienced the poorer QOL compared to DGRY in the 15 of 19 main outcome measures of PGSAS-45. Moreover, multiple regression analysis indicated that the type of gastrectomy, TGRY, most strongly and broadly impaired the postoperative QOL among six explanatory variables. CONCLUSION The results of the present study suggested that TGRY had a certain detrimental impact on the postoperative QOL, and the loss of reservoir capacity could be a major cause. PMID:28373774

  14. The Blocking Effect of Phenolic Acid on N—Nitrosomorholine Formation in vitro

    Institute of Scientific and Technical Information of China (English)

    LIPING; WANGHuai-Zhou; 等

    1994-01-01

    Phenolic acid(PAs) are widely found in many daily consumed vegetables and fruits.The inhibitory effects of PAs on N-nitrosomorpholine(NMOR)formation in vitro under simulated gastric juice condition were studied.The results showed that the inhibitory potncy of thirteen varieties of PAs differed greatly,which may be related to their chemical structures;the blockine rate(BR)of different kinds of PAs were as follows:caffeic acid,92.5%;tannic acid,90.0%;gallic acid,86.8%;sinapinic acid,86.2%;ferulic acid,81.1%;chlorogenic acid,69.4%;gentisic acid,69.2%;syringic acid,62.1%;protocatechuic acid,56.0%;p-coumaric acid,52.5%;vannilic acid,35.4%;moreover,p-hydroxybenzoic acid and m-coumaric acid had the least blocking effect or even slight catalyzing effect.The results also demonstrated that amounts of NMOR formed were negatively correlated with molar ratio of PAs to nitrite and that the optimum pH for inhibition was betwwen 2 and 3 .

  15. Early association of electrocardiogram alteration with infarct size and cardiac function after myocardial infarction

    Institute of Scientific and Technical Information of China (English)

    TAO Ze-wei (陶则伟); HUANG Yuan-wei (黄元伟); XIA Qiang (夏强); FU Jun (傅军); ZHAO Zhi-hong (赵志宏); LU Xian (陆贤); BRUCE I.C.

    2004-01-01

    Objective: Myocardial infarction (MI) is the main cause of heart failure, but the relationship between the extent of MI and cardiac function has not been clearly determined. The present study was undertaken to investigate early changes in the electrocardiogram associated with infarct size and cardiac function after MI. Methods: MI was induced by ligating the left anterior descending coronary artery in rats. Electrocardiograms, echocardiographs and hemodynamic parameters were assessed and myocardial infarct size was measured from mid-transverse sections stained with Masson's trichrome. Results: The sum of pathological Q wave amplitudes was strongly correlated with myocardial infarct size (r = 0.920, P < 0.0001), left ventricular ejection fraction (r = (0.868, P < 0.0001) and left ventricular end diastolic pressure (r = 0.835, P < 0.0004). Furthermore, there was close relationship between MI size and cardiac function as assessed by left ventricular ejection fraction (r = (0.913, P < 0.0001) and left ventricular end diastolic pressure (r = 0.893, P < 0.0001). Conclusion: The sum of pathological Q wave amplitudes after MI can be used to estimate the extent of MI as well as cardiac function.

  16. A Research of the Track of CUI Zhiyuan in China%崔致远在中国行迹考

    Institute of Scientific and Technical Information of China (English)

    祁庆富

    2002-01-01

    崔致远是韩国历史上最著名的文学家、诗人.他12岁赴唐留学,仕宦溧水,就职淮南,在中国生活16年,东归新罗.他写下著名的,流传至今.在数千年中韩文化交流史上,崔致远是当之无愧的第一名人.经考证,崔致远入华年代是868年,任溧水县尉在876年,880年冬投淮南,884年初冬离开扬州东归,885年回到新罗.他创作的诗文集名,中山即溧水古称.桂苑是南京古代名苑,喻淮南.归国时,自扬州乘船,沿大运河北行,经过淮安入海.暂泊东海(今连云港),到达山东乳山口.他在乳山度过春节,留下十篇诗文,是中韩文化交流宝库中一颗永放光彩的明珠.

  17. An Improved Analysis of the Sevoflurane-Benzene Structure by Chirped Pulse Ftmw Spectroscopy

    Science.gov (United States)

    Seifert, Nathan A.; Perez, Cristobal; Zaleski, Daniel P.; Neill, Justin L.; Pate, Brooks H.; Lesarri, Alberto; Vallejo, Montserrat; Cocinero, Emilio J.; Castano, Fernando; Kleiner, Isabelle

    2013-06-01

    Recent improvements to the 2-8 GHz CP-FTMW spectrometer at University of Virginia have improved the structural and spectroscopic analysis of the sevoflurane-benzene cluster. Previously reported results, although robust, were limited to a fit of the a-type transitions of the normal species in the determination of the six-fold barrier to benzene internal rotation. Structural analysis was limited to the benzene hydrogen atom positions using benzene-d_{1}. The increased sensitivity of the new 2-8 GHz setup allows for a full internal rotation analysis of the a- and c-type transitions of the normal species, which was performed with BELGI. A fit value for V_{6} of 32.868(11) cm^{-1} is determined. Additionally, a full substitution structure of the benzene carbon atom positions was determined in natural abundance. Also, new measurements of a sevoflurane/benzene-d_{1} mixture enabled detection of 33 of the 60 possible ^{2}D / ^{13}C double isotopologues. This abundance of isotopic data, a total of 45 isotopologues, enabled a full heavy atom least-squares r_{0} structure fit for the complex, including positions for all seven fluorines in sevoflurane. N. A. Seifert, D. P. Zaleski, J. L. Neill, B. H. Pate, A. Lesarri, M. Vallejo, E. J. Cocinero, F. Castańo. 67th OSU Int. Symp. On Mol. Spectrosc., Columbus, OH, 2012, MH13.

  18. Optimization of ultrasonic-assisted extraction and radical-scavenging capacity of phenols and flavonoids from Clerodendrum cyrtophyllum Turcz leaves.

    Science.gov (United States)

    Zhou, Jing; Zheng, Xiaoxue; Yang, Qi; Liang, Zhenyi; Li, Donghai; Yang, Xiaobo; Xu, Jing

    2013-01-01

    Ultrasonic-assisted extraction (UAE) was developed to extract phenolic and flavonoid antioxidants from Clerodendrum cyrtophyllum Turcz leaves. The optimal experimental parameters for antioxidant extraction from C. cyrtophyllum leaves were measured using single-factor experimentation combined with response surface methodology (RSM). Total phenolic content (TPC) and total flavonoid content (TFC) assays were used to quantify antioxidant compounds. Next, antioxidant radical scavenging capacity was measured using 2,2'-diphenyl-1-picrylhydrazyl (DPPH) and 2,2' -azino-bis(3-ethylbenzothiazoline-6-sulphonicacid) (ABTS) radicals. Optimized extraction conditions for UAE from C. cyrtophyllum leaves were as follows: 60.9% ethanol, 85.4 min, and 63.3°C for maximal TPC extraction (16.8 ± 0.2 mg GAE/g DW); 67.7% ethanol, 82.9 min, and 63.0 °C for maximal TFC extraction (49.3 ± 0.4 mg RT/g DW); 48.8% ethanol, 85.1 min, and 63.9 °C for maximal DPPH radical-scavenging capacity (86.8 ± 0.2%); and 50.6% ethanol, 81.3 min, and 63.4 °C for maximal ABTS radical-scavenging capacity (92.9 ± 0.5%). Ethanol concentration was the most important factor in the extraction process. Our work offers optimal extraction conditions for C. cyrtophyllum as a potential source of natural antioxidants.

  19. Clinical Outcomes of Volume-Modulated Arc Therapy in 205 Patients with Nasopharyngeal Carcinoma: An Analysis of Survival and Treatment Toxicities.

    Directory of Open Access Journals (Sweden)

    Rui Guo

    Full Text Available To investigate the clinical efficacy and treatment toxicity of volume-modulated arc therapy (VMAT for nasopharyngeal carcinoma (NPC.205 VMAT-treated NPC patients from our cancer center were prospectively entrolled. All patients received 68-70 Gy irradiation based on the planning target volume of the primary gross tumor volume. Acute and late toxicities were graded according to the Common Terminology Criteria for Adverse Events v3.0 and Radiation Therapy Oncology Group Late Radiation Morbidity Scoring Criteria.The median follow-up period was 37.3 months (range, 6.3-45.1 months. The 3-year estimated local failure-free survival, regional failure-free survival, locoregional failure-free survival, distant metastasis-free survival, disease-free survival and overall survival were 95.5%, 97.0%, 94.0%, 92.1%, 86.8% and 97.0%, respectively. Cox regression analysis showed primary gross tumor volume, N stage and EBV-DNA to be independent predictors of VMAT outcomes (P < 0.05. The most common acute and late side effects were grade 2-3 mucositis (78% and xerostomia (83%, 61%, 34%, and 9% at 3, 6, 12 and 24 months after VMAT, respectively.VMAT for the primary treatment of NPC achieved very high locoregional control with a favorable toxicity profile. The time-saving benefit of VMAT will enable more patients to receive precision radiotherapy.

  20. Avaliação genética de seleções e híbridos de limões cravo, volkameriano e rugoso como porta-enxertos para laranjeiras Valência na presença da morte súbita dos citros Genetic evaluation of selections and hybrids of rangpur lime, volkamer and rough lemons rootstocks for Valência orange trees in the presence of the citrus sudden death

    Directory of Open Access Journals (Sweden)

    Jorgino Pompeu Junior

    2013-03-01

    Full Text Available Este estudo teve como objetivo realizar a avaliação genética da produção de frutos, eficiência produtiva e altura de laranjeiras Valência (Citrus sinensis enxertadas em seleções e híbridos dos limões Cravo (C. limonia, Volkameriano (C. volkameriana e Rugoso (C. jambhiri, em área endêmica para morte súbita dos citros (MSC. Foram avaliados 36 genótipos desses porta-enxertos, representados por cinco plantas cada, avaliados em cinco safras, do terceiro ao sétimo ano após o plantio. Sete dos genótipos avaliados apresentaram plantas com sintomas de MSC até o sétimo ano: Rangpur Otaheite orange 12901 (859, Rangpur Red Lime D.33.30 (866, Limão-Cravo EEL (871, Rangpur Borneo red (874, Citrus kokhai (1649, Limão-Rugoso 58329 (1655 e Limão- Cravo x Swingle B (1695. Para os genótipos que não manifestaram sintomas da doença, foram estimados parâmetros genéticos e fenotípicos e realizada a predição de valores genéticos dos indivíduos, visando à seleção e ao melhoramento genético para as características citadas, empregando-se o método REML/BLUP (máxima verossimilhança restrita/melhor predição linear não viciada. A análise de produção de frutos de cinco safras mostrou acurácia seletiva de 84,59%, tornando-se desnecessária a avaliação de maior número de safras. A seleção dos sete melhores genótipos proporcionou ganhos genéticos de 11,5% na produção de frutos, enquanto a do melhor genótipo conferiu ganho genético de 16,3%. As maiores médias genéticas preditas (>70,0 kg.pl-1 para produção de frutos foram obtidas pelos genótipos Limão-Cravo- Ipanema (1522, Santa- Bárbara-Red- Lime (884, Limão- Cravo- Limeira (863, Limão- Cravo- Taquaritinga (869, Limão- Rugoso- do -Cabo (1643, Rangpur- Rose Lime (868 e Limão- Cravo- da- Califórnia (1467. Já a acurácia seletiva da eficiência produtiva, para quatro colheitas, foi 77,4%. Para este caráter, as maiores médias genéticas (>8,0 kg.m-3 foram dos

  1. Refractive outcomes comparison between the Lenstar LS 900® optical biometry and immersion A-scan ultrasound.

    Science.gov (United States)

    Naicker, Palanyraj; Sundralingam, Siva; Peyman, Mohammadreza; Juana, Azida; Mohamad, Nor Fadhilah; Win, Maung Maung; Loo, Angela; Subrayan, Visvaraja

    2015-08-01

    To determine the accuracy of intraocular lens (IOL) calculations in eyes undergoing phacoemulsification cataract surgery with IOL implantation using immersion A-scan ultrasound (US) and Lenstar LS 900(®) biometry. In this prospective study, 200 eyes of 200 patients were randomized to undergo either Lenstar LS 900(®) or immersion A-scan US biometry to determine the IOL dioptric power prior to phacoemulsification cataract surgery. Post-operative refractive outcomes of these two groups of patients were compared. The result showed no significant difference between the target spherical equivalent (SE) and the post-operative SE value by the Lenstar LS 900(®) (p value = 0.632) or immersion A-scan US biometry (p value = 0.438) devices. The magnitude of difference between the two biometric devices were not significantly different (p value = 0.868). There was no significant difference in the predicted post-operative refractive outcome between immersion A-scan US biometry and Lenstar LS 900(®). Based on the results, the immersion A-scan US technique is as accurate as Lenstar LS 900(®) in the hands of an experienced operator.

  2. 云南省O139霍乱弧菌引起的一次食源性霍乱爆发

    Institute of Scientific and Technical Information of China (English)

    杨汝松; 吴强; 王树坤; 姚颖波; 刘红雁

    2010-01-01

    @@ 霍乱是由O1霍乱弧菌(Vibrio cholerae O1)或O139霍乱弧菌(Vibrio cholerae O139)引起的一种肠道传染病,是发展中国家的一个主要公共卫生问题,2000年以来世界卫生组织每年报告霍乱病例数范围是101383~184311例,其中非洲报告病例数占86.8%~96.9%,亚洲占3.1%~8.2%,拉丁美洲占0.0%~2.3%,非洲、亚洲和拉丁美洲报告病死率范围分别是1.7%~3.3%、0.3%~0.6%和0.0%[1].

  3. Optical Studies of Twenty Longer-Period Cataclysmic Binaries

    CERN Document Server

    Thorstensen, John R; Skinner, Julie N

    2010-01-01

    We obtained time-series radial velocity spectroscopy of twenty cataclysmic variable stars, with the aim of determining orbital periods P_orb. All of the stars reported here prove to have P_orb > 3.5 h. For sixteen of the stars, these are the first available period determinations, and for the remaining four (V709 Cas, AF Cam, V1062 Tau, and RX J2133+51) we use new observations to improve the accuracy of previously-published periods. Most of the targets are dwarf novae, without notable idiosyncracies. Of the remainder, three (V709 Cas, V1062 Tau, and RX J2133+51) are intermediate polars (DQ Her stars); one (IPHAS 0345) is a secondary-dominated system without known outbursts, similar to LY UMa; one (V1059 Sgr) is an old nova; and two others (V478 Her and V1082 Sgr) are long-period novalike variables. The stars with new periods are IPHAS 0345 (0.314 d); V344 Ori (0.234 d); VZ Sex (0.149 d); NSVS 1057+09 (0.376 d); V478 Her (0.629 d); V1059 Sgr (0.286 d); V1082 Sgr (0.868 d); FO Aql (0.217 d); V587 Lyr (0.275 d); ...

  4. Determination of sex from the hyoid bone in a contemporary White population.

    Science.gov (United States)

    Logar, Ciara J; Peckmann, Tanya R; Meek, Susan; Walls, Stephen G

    2016-04-01

    Six discriminant functions, developed from an historic White population, were tested on a contemporary White population for determination of sex from the hyoid. One hundred and thirty four fused and unfused hyoids from a contemporary White population were used. Individuals ranged between 20 and 49 years old. Six historic White discriminant functions were applied to the fused and unfused hyoids of the pooled contemporary White population, i.e. all males and females and all age ranges combined. The overall accuracy rates were between 72.1% and 92.3%. Correct sex determination for contemporary White males ranged between 88.2% and 96.3%, while correct sex determination for contemporary White females ranged between 31.3% and 92.0%. Discriminant functions were created for the contemporary White population with overall mean accuracy rates between 67.0% and 93.0%. The multivariate discriminant function overall accuracy rates were between 89.0% and 93.0% and the univariate discriminant function overall accuracy rates were between 67.0% and 86.8%. The contemporary White population data were compared to other populations and showed significant differences between many of the variables measured. This study illustrated the need for population-specific and temporally-specific discriminant functions for determination of sex from the hyoid bone.

  5. Preparation of a graphene-based magnetic nanocomposite for the extraction of carbamate pesticides from environmental water samples.

    Science.gov (United States)

    Wu, Qiuhua; Zhao, Guangying; Feng, Cheng; Wang, Chun; Wang, Zhi

    2011-11-04

    A graphene-based magnetic nanocomposite was synthesized and used for the first time as an effective adsorbent for the preconcentration of the five carbamate pesticides (metolcarb, carbofuran, pirimicarb, isoprocarb and diethofencarb) in environmental water samples prior to high performance liquid chromatography-diode array detection. The properties of the magnetic nanocomposite were characterized by scanning electron microscopy and X-ray diffraction. This novel graphene-based magnetic nanocomposite showed great adsorptive ability towards the analytes. The method, which takes the advantages of both nanoparticle adsorption and magnetic phase separation from the sample solution, could avoid some of the time-consuming experimental procedures related to the traditional solid phase extraction. Various experimental parameters that could affect the extraction efficiencies have been investigated. Under the optimum conditions, the enrichment factors of the method for the analytes were in the range from 474 to 868. A linear response was achieved in the concentration range of 0.1-50 ng mL(-1). The limits of detection of the method at a signal to noise ratio of 3 for the pesticides were 0.02-0.04 ng mL(-1). Compared with the dispersive liquid-liquid microextraction and the ultrasound-assisted surfactant-enhanced emulsification microextraction, much higher enrichment factors and sensitivities were achieved with the developed method. The method has been successfully applied for the determination of the carbamate pesticides in environmental water samples.

  6. Comparison of the Fenwal Amicus and Fresenius Com.Tec cell separators for autologous peripheral blood progenitor cell collection.

    Science.gov (United States)

    Altuntas, Fevzi; Kocyigit, Ismail; Ozturk, Ahmet; Kaynar, Leylagul; Sari, Ismail; Oztekin, Mehmet; Solmaz, Musa; Eser, Bulent; Cetin, Mustafa; Unal, Ali

    2007-04-01

    Peripheral blood progenitor cells (PBPC) are commonly used as a stem cell source for autologous transplantation. This study was undertaken to evaluate blood cell separators with respect to separation results and content of the harvest. Forty autologous PBPC collections in patients with hematological malignancies were performed with either the Amicus or the COM.TEC cell separators. The median product volume was lower with the Amicus compared to the COM.TEC (125 mL vs. 300 mL; p COM.TEC (3.0 x 10(6) vs. 4.1 x 10(6); p = 0.129). There was a statistically higher mean volume of ACD used in collections on the Amicus compared to the COM.TEC (1040 +/- 241 mL vs. 868 +/- 176 mL; p = 0.019). There was a statistical difference in platelet (PLT) contamination of the products between the Amicus and the COM.TEC (0.3 x 10(11) vs. 1.1 x 10(11); p COM.TEC compared to the Amicus instruments (18.5% vs. 9.5%; p = 0.028). In conclusion, both instruments collected PBPCs efficiently. However, Amicus has the advantage of lower PLT contamination in the product, and less decrease in PB platelet count with lower product volume in autologous setting.

  7. Validación de la prueba "Sentido del Trabajo" en población colombiana

    Directory of Open Access Journals (Sweden)

    Efrén Martínez Ortiz

    2012-01-01

    Full Text Available Se evaluaron las características psicométricas de validez y confiabilidad del instrumento "Sentido del trabajo", así como sus dimensiones experiencia (Cognición y vivencia (Afectividad. El cuestionario se aplicó a 842 empleados de los niveles operativo, medio y alto de organizaciones tanto del sector público como privado seleccionados intencionalmente previa construcción y revisión por jueces expertos y posterior pilotaje. La versión final, compuesta por 18 reactivos, mostró un nivel de respuesta a la totalidad de los ítems del 86,8% y una consistencia interna con el alfa de Cronbach de 0.83. Se realizó un análisis factorial exploratorio que identificó 3 componentes consistentes con la estructura teórica: Confusión existencial-laboral, Propósito-laboral e Identidad y Coherencia laboral. Se presenta un instrumento de fácil aplicabilidad en la consulta individual y en la valoración colectiva, con utilidad para el abordaje de problemáticas relacionadas con esta característica de la naturaleza humana.

  8. Evaluation on Cultivated Land Resource Ecologi-cal Service Value in Wuhan Metropolitan Area

    Institute of Scientific and Technical Information of China (English)

    Jinhua TANG; Yinghui Ll; Gangqiang CHEN; Lei YU; Sujuan Ll

    2014-01-01

    The land ecosystem service function value contains the gas regulating function value, air purification function value, water conservation value, land conser-vation value, soil nutrient conservation value and maintain biodiversity value. Based on the method of market value and the data of Hubei Statistical yearbook, cultivat-ed land resources of ecosystem service function value is 730 038.69Mil ion in 2007-2009, and 714 774.99 Mil ion in 2010-2012 in Wuhan Metropolitan Area. After three years of development, Wuhan Metropolitan Area of ecological value of cultivated land has increased by about 3.97%. From the point of each composition, the im-portance of gas regulating function of cultivated land resources and water conserva-tion function is the forefront. From the point of spatial distribution, the highest of annual average value of the cultivated land ecological was Huanggang (1.725 bil ion yuan), the lowest was Ezhou (217.868 6 mil ion yuan) in 2010-2012. From the point of space changes, the land ecological value increased only in Qianjiang city, while farmland ecological value in other cities was fal ing The conclusion is of direc-tive significance to the regional land protection policy and the farmland reasonable distribution, for Wuhan Metropolitan Area and other areas.

  9. Conventional versus Analgesia-Oriented Combination Sedation on Recovery Profiles and Satisfaction after ERCP: A Randomized Trial

    Science.gov (United States)

    Chung, Moon Jae; Park, Jeong Youp; Park, Seung Woo; Chung, Jae Bok; Song, Si Young; Cho, Jooyoun; Park, Sang-Hun; Yoo, Young Chul; Bang, Seungmin

    2015-01-01

    Background The importance of providing effective analgesia during sedation for complex endoscopic procedures has been widely recognized. However, repeated administration of opioids in order to achieve sufficient analgesia may carry the risk of delayed recovery after propofol based sedation. This study was done to compare recovery profiles and the satisfaction of the endoscopists and patients between conventional balanced propofol sedation and analgesia-oriented combination sedation for patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). Methods Two hundred and two adult patients scheduled for ERCP were sedated by either the Conventional (initial bolus of meperidine with propofol infusion) or Combination (repeated bolus doses of fentanyl with propofol infusion) method. Recovery profiles, satisfaction levels of the endoscopists and patients, drug requirements and complications were compared between groups. Results Patients of the Combination Group required significantly less propofol compared to the Conventional Group (135.0 ± 68.8 mg vs. 165.3 ± 81.7 mg, P = 0.005). Modified Aldrete scores were not different between groups throughout the recovery period, and recovery times were also comparable between groups. Satisfaction scores were not different between the two groups in both the endoscopists and patients (P = 0.868 and 0.890, respectively). Conclusions Considering the significant reduction in propofol dose, the non-inferiority of recovery profiles and satisfaction scores of the endoscopists and patients, analgesia oriented combination sedation may be a more safe yet effective sedative method compared to conventional balanced propofol sedation during ERCP. PMID:26402319

  10. Conventional versus Analgesia-Oriented Combination Sedation on Recovery Profiles and Satisfaction after ERCP: A Randomized Trial.

    Directory of Open Access Journals (Sweden)

    Seokyung Shin

    Full Text Available The importance of providing effective analgesia during sedation for complex endoscopic procedures has been widely recognized. However, repeated administration of opioids in order to achieve sufficient analgesia may carry the risk of delayed recovery after propofol based sedation. This study was done to compare recovery profiles and the satisfaction of the endoscopists and patients between conventional balanced propofol sedation and analgesia-oriented combination sedation for patients undergoing endoscopic retrograde cholangiopancreatography (ERCP.Two hundred and two adult patients scheduled for ERCP were sedated by either the Conventional (initial bolus of meperidine with propofol infusion or Combination (repeated bolus doses of fentanyl with propofol infusion method. Recovery profiles, satisfaction levels of the endoscopists and patients, drug requirements and complications were compared between groups.Patients of the Combination Group required significantly less propofol compared to the Conventional Group (135.0 ± 68.8 mg vs. 165.3 ± 81.7 mg, P = 0.005. Modified Aldrete scores were not different between groups throughout the recovery period, and recovery times were also comparable between groups. Satisfaction scores were not different between the two groups in both the endoscopists and patients (P = 0.868 and 0.890, respectively.Considering the significant reduction in propofol dose, the non-inferiority of recovery profiles and satisfaction scores of the endoscopists and patients, analgesia oriented combination sedation may be a more safe yet effective sedative method compared to conventional balanced propofol sedation during ERCP.

  11. ANALYSIS OF POTENTIAL INTENSITY OF SEDIMENT TRANSPORT ON SELECTED REACH OF THE NER RIVER

    Directory of Open Access Journals (Sweden)

    Ewelina Szałkiewicz

    2015-11-01

    Full Text Available The aim of this study was to perform a simulation of sediment transport for the section of the river Ner, while also utilizing GIS tools. Using the ArcGIS numerical model of channel and stream valleys were developed, and motion simulations and sediment transport set for 5 ten-year periods were performed in HEC-RAS. Updated geometries after the simulations were created using the tools of RAS Mapper. ArcGIS was used again for analysing the results. It was used to generate ordinates of bottom in the initial state and final. The difference between them illustrated the magnitude of erosion and accumulation. The process of erosion occurred in 13 sections of the analysed model (the standard differential ordinates negative, while the accumulation in 53 sections. The maximum value of shallowing bottom was 1.24 m (cross-section at km 18 + 868, while the largest deepening occurred at km 8 + 654 (– 0.76 m. All values, using ArcGIS, were marked on othophotomap.

  12. Patients receiving androgen deprivation therapy for prostate cancer have an increased risk of depressive disorder

    Science.gov (United States)

    Chung, Shiu-Dong; Xirasagar, Sudha

    2017-01-01

    Androgen deprivation therapy (ADT) results in testosterone suppression, a hypothesized mechanism linking ADT to depressive symptoms. This study investigated the relationship between ADT and the risk of subsequently being diagnosed with depressive disorder (DD) during a 3-year follow-up period. The patient sample for this population-based, retrospective cohort study was retrieved from the Taiwan Longitudinal Health Insurance Database 2005. We included all 1714 patients aged over 40 years with a first-time diagnosis of prostate cancer (PC) during 2001 to 2010 who did not have an orchiectomy. Among them, we defined 868 patients who received ADT during the 3-year follow-up period as the study group, and 846 patients who did not receive ADT as the comparison group. The incidence rates of DD per 1000 person-years were 13.9 (95% confidence interval (CI): 9.5~19.6) and 6.7 (95% CI: 3.7~11.0), respectively. Cox proportional hazard regressions showed that the adjusted hazard ratio for DD for ADT recipients was 1.93 (95% CI: 1.03~3.62) relative to the comparison group. This study presents epidemiological evidence of an association between ADT and a subsequent DD diagnosis. PMID:28253340

  13. Photometric Redshifts of Galaxies in COSMOS

    CERN Document Server

    Mobasher, B; Scoville, N Z; Dahlen, T; Salvato, M; Aussel, H; Thompson, D J; Feldmann, R; Tasca, L; Lefèvre, O; Lilly, S; Carollo, C M; Kartaltepe, J S; McCracken, H; Mould, J; Renzini, A; Sanders, D B; Shopbell, P L; Taniguchi, Y; Ajiki, M; Shioya, Y; Contini, T; Giavalisco, M; Ilbert, O; Iovino, A; Le Brun, V; Mainieri, V; Mignoli, M; Scodeggio, M

    2006-01-01

    We measure photometric redshifts and spectral types for galaxies in the COSMOS survey. We use template fitting technique combined with luminosity function priors and with the option to simultaneously estimate dust extinction (i.e. E(B-V)) for each galaxy.Our estimated redshifts are accurate to i<25 and z~1.2. Using simulations with sampling and noise characteristics similar to those in COSMOS, the accuracy and reliability is estimated for the photometric redshifts as a function of the magnitude limits of the sample, S/N ratios and the number of bands used. From the simulations we find that the ratio of derived 95% confidence interval in the redshift probability distribution to the estimated photometric redshift (D95) can be used to identify and exclude the catastrophic failures in the photometric redshift estimates. We compare the derived redshifts with high-reliability spectroscopic redshifts for a sample of 868 normal galaxies with z < 1.2 from zCOSMOS. Considering different scenarios, depending on us...

  14. Transplantation of mobilized peripheral blood mononuclear cells for peripheral arterial occlusive disease of the lower extremity

    Institute of Scientific and Technical Information of China (English)

    Xiaofeng YANG; Yanxiang WU; Hongmei WANG; Yifeng XU; Bo XU; Xin LU; Yibin ZANG; Fa WANG; Yue ZHANG

    2006-01-01

    Objectives To assess the clinical efficacy, safety, and feasibility of autologous transplantation of mobilized peripheral blood mononuclear cells (PBMNCs) for patients with peripheral arterial occlusive disease (PAOD) of the lower extremity. Methods A total of 152 patients with PAOD of the lower extremity were enrolled into this non-controlled observational study from November 2003 to March 2006. All patients received subcutaneous injections of recombinant human granulocyte colony-stimulating factor (G-CSF, 450600 μg/day) for 5 days in order to mobilize stem/progenitor cells; their PBMNCs were collected and transplanted by multiple intramuscular injections into ischemic limbs. Patients were followed up for at least 12 weeks. Results At 12 weeks, primarymanifestations,including lower limb pain and coldness, were significantly improved in 137 (90.1%) of the patients; limb ulcers improved or healed in 46 (86.8%) of the 53 patients, while 25 of the 48 (47.9%) patients with limb gangrene remained steady or improved. Ankle-brachial index (ABI) improved in 33 (22%) of the cases, and TcPO2 increased in 45 (30%) of the cases. Angiography before treatment, and at 12 weeks after treatment, was performed in 10 of the patients and showed formation of new collateral vessels. No severe adverse effects or complications specifically related to cell transplantation were observed. Conclusion Autologous transplantation of G-CSF-mobilized PBMNCs might be a safe and effective treatment for lower limb ischemic disorder.(J Geriatr Cardiol 2006; 3:178-80.)

  15. 影响乳腺癌保乳术后美容效果相关因素的分析%Factors Associated with Cosmetic Outcome in Breast Conserving Surgery

    Institute of Scientific and Technical Information of China (English)

    贾海霞; 夏婷; 曹腾飞; 胡小戊; 章乐虹

    2012-01-01

      目的探讨影响乳腺癌保乳术后美容效果的相关因素.方法对2005年9月-2010年9月于我院收治的221例保乳患者进行美容效果的评价.分析乳房体积、切除边缘次数以及肿瘤大小对于保乳术后美容效果的影响.结果保乳术后患者总体满意率为83.3%(184/221).肿瘤大小≤3cm与>3cm患者术后满意率分别为86.8%和45.5%(P3cm, respectively(P<0.05). Breast volume and excision times had no effects on cosmetic result. Conclusion Tumor size is the important factor that influences the breast conserving cosmetic outcome, not breast volume and excision times.

  16. Risk-Adjusted Analysis of Relevant Outcome Drivers for Patients after More Than Two Kidney Transplants

    Directory of Open Access Journals (Sweden)

    Lampros Kousoulas

    2015-01-01

    Full Text Available Renal transplantation is the treatment of choice for patients suffering end-stage renal disease, but as the long-term renal allograft survival is limited, most transplant recipients will face graft loss and will be considered for a retransplantation. The goal of this study was to evaluate the patient and graft survival of the 61 renal transplant recipients after second or subsequent renal transplantation, transplanted in our institution between 1990 and 2010, and to identify risk factors related to inferior outcomes. Actuarial patient survival was 98.3%, 94.8%, and 88.2% after one, three, and five years, respectively. Actuarial graft survival was 86.8%, 80%, and 78.1% after one, three, and five years, respectively. Risk-adjusted analysis revealed that only age at the time of last transplantation had a significant influence on patient survival, whereas graft survival was influenced by multiple immunological and surgical factors, such as the number of HLA mismatches, the type of immunosuppression, the number of surgical complications, need of reoperation, primary graft nonfunction, and acute rejection episodes. In conclusion, third and subsequent renal transplantation constitute a valid therapeutic option, but inferior outcomes should be expected among elderly patients, hyperimmunized recipients, and recipients with multiple operations at the site of last renal transplantation.

  17. Kinetics of hexavalent chromium reduction by iron metal

    Institute of Scientific and Technical Information of China (English)

    Huijing QIAN; Yanjun WU; Yong LIU; Xinhua XU

    2008-01-01

    The kinetics of Cr(Ⅵ) reduction to Cr(Ⅲ) by metallic iron (Fe0) was studied in batch reactors for a range of reactant concentrations, pH and temperatures. Nearly 86.8% removal efficiency for Cr(Ⅵ) was achieved when Fe0 concentration was 6 g/L (using commercial iron powder (200 mesh) I n 120 min). The reduction ofhexavalent chro-mium took place on the surface of the iron particles following pseudo-first order kinetics. The rate of Cr(Ⅵ) reduction increased with increasing Fe0 addition and temperature but inversely with initial pH. The pseudo-first-order rate coeffi-cients (kobs) were determined as 0.0024, 0.010, 0.0268 and 0.062 8 min-1 when iron powder dosages were 2, 6, 10 and 14 g/L at 25℃ and pH 5.5, respectively. According to the Arrehenius equation, the apparent activation energy of 26.5 kJ/mol and pre-exponential factor of 3 330 min-1 were obtained at the temperature range of 288-308 K. Different Fe0 types were compared in this study. The reactivity was in the order starch-stabilized Fe0 nanoparticlesFe0 nano-particlesFe0 powderFe0 filings. Electrochemical analysis of the reaction process showed that Cr(Ⅲ) and Fe(Ⅲ) hydroxides should be the dominant final products.

  18. Highly specific changes in antioxidant levels and lipid peroxidation in Parkinson's disease and its progression: Disease and staging biomarkers and new drug targets.

    Science.gov (United States)

    de Farias, Carine Coneglian; Maes, Michael; Bonifácio, Kamila Landucci; Bortolasci, Chiara Cristina; de Souza Nogueira, André; Brinholi, Francis Fregonesi; Matsumoto, Andressa Keiko; do Nascimento, Matheus Amarante; de Melo, Lúcio Baena; Nixdorf, Suzana Lucy; Lavado, Edson Lopes; Moreira, Estefânia Gastaldello; Barbosa, Décio Sabbatini

    2016-03-23

    There is evidence that immune-inflammatory, stress of reactive oxygen and nitrogen species (IO&NS) processes play a role in the neurodegenerative processes observed in Parkinson's disease (PD). The aim of the present study was to investigate peripheral IO&NS biomarkers in PD. We included 56 healthy individuals and 56 PD patients divided in two groups: early PD stage and late PD stage. Plasma lipid hydroperoxides (LOOH), malondialdehyde (MDA), nitric oxide metabolites (NOx), sulfhydryl (SH) groups, catalase (CAT) activity, superoxide dismutase (SOD) activity, paraoxonase (PON)1 activity, total radical trapping antioxidant parameter (TRAP) and C-reactive protein (CRP) were measured. PD is characterized by increased LOOH, MDA and SOD activity and lowered CAT activity. A combination of five O&NS biomarkers highly significantly predicts PD with a sensitivity of 94.5% and a specificity of 86.8% (i.e., MDA, SOD activity, TRAP, SH-groups and CAT activity). The single best biomarker of PD is MDA, while LOOH and SOD activity are significantly associated with late PD stage, but not early PD stage. Antiparkinson drugs did not affect O&NS biomarkers, but levodopa+carbidopa significantly increased CRP. It is suggested that MDA may serve as a disease biomarker, while LOOH and SOD activity are associated with late PD stage characteristic. New treatments for PD should not only target dopamine but also lipid peroxidation.

  19. Unsupervised segmentation of heel-strike IMU data using rapid cluster estimation of wavelet features.

    Science.gov (United States)

    Yuwono, Mitchell; Su, Steven W; Moulton, Bruce D; Nguyen, Hung T

    2013-01-01

    When undertaking gait-analysis, one of the most important factors to consider is heel-strike (HS). Signals from a waist worn Inertial Measurement Unit (IMU) provides sufficient accelerometric and gyroscopic information for estimating gait parameter and identifying HS events. In this paper we propose a novel adaptive, unsupervised, and parameter-free identification method for detection of HS events during gait episodes. Our proposed method allows the device to learn and adapt to the profile of the user without the need of supervision. The algorithm is completely parameter-free and requires no prior fine tuning. Autocorrelation features (ACF) of both antero-posterior acceleration (aAP) and medio-lateral acceleration (aML) are used to determine cadence episodes. The Discrete Wavelet Transform (DWT) features of signal peaks during cadence are extracted and clustered using Swarm Rapid Centroid Estimation (Swarm RCE). Left HS (LHS), Right HS (RHS), and movement artifacts are clustered based on intra-cluster correlation. Initial pilot testing of the system on 8 subjects show promising results up to 84.3%±9.2% and 86.7%±6.9% average accuracy with 86.8%±9.2% and 88.9%±7.1% average precision for the segmentation of LHS and RHS respectively.

  20. Classifying Step and Spin Turns Using Wireless Gyroscopes and Implications for Fall Risk Assessments

    Directory of Open Access Journals (Sweden)

    Peter C. Fino

    2015-05-01

    Full Text Available Recent studies have reported a greater prevalence of spin turns, which are more unstable than step turns, in older adults compared to young adults in laboratory settings. Currently, turning strategies can only be identified through visual observation, either in-person or through video. This paper presents two unique methods and their combination to remotely monitor turning behavior using three uniaxial gyroscopes. Five young adults performed 90° turns at slow, normal, and fast walking speeds around a variety of obstacles while instrumented with three IMUs (attached on the trunk, left and right shank. Raw data from 360 trials were analyzed. Compared to visual classification, the two IMU methods’ sensitivity/specificity to detecting spin turns were 76.1%/76.7% and 76.1%/84.4%, respectively. When the two methods were combined, the IMU had an overall 86.8% sensitivity and 92.2% specificity, with 89.4%/100% sensitivity/specificity at slow speeds. This combined method can be implemented into wireless fall prevention systems and used to identify increased use of spin turns. This method allows for longitudinal monitoring of turning strategies and allows researchers to test for potential associations between the frequency of spin turns and clinically relevant outcomes (e.g., falls in non-laboratory settings.