WorldWideScience

Sample records for alloy-ehi 826

  1. 32 CFR 700.826 - Physical security.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Physical security. 700.826 Section 700.826... Commanding Officers in General § 700.826 Physical security. (a) The commanding officer shall take appropriate... officer shall take action to protect and maintain the security of the command against dangers from...

  2. 43 CFR 4.826 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... the Interior-Effectuation of Title VI of the Civil Rights Act of 1964 Procedures § 4.826 Discovery. (a) Methods. Parties may obtain discovery as provided in these rules by depositions, written interrogatories... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Discovery. 4.826 Section 4.826...

  3. Dicty_cDB: SSA826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSA826 (Link to dictyBase) - - - Contig-U00472-1 SSA826Z (Link... to Original site) - - SSA826Z 395 - - - - Show SSA826 Library SS (Link to library) Clone ID SSA826 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SS/SSA8-B/SSA826Q.Seq.d/ Representative seq. ID SSA82...6Z (Link to Original site) Representative DNA sequence >SSA826 (SSA826Q) /CSM/SS/SSA8-B/SSA826Q.Seq.d/ XXXXX...cmlessltpptinphrnq*ndhhgtvhitn*shspkitstth*tfgdlyr fkskssakcfpigskin*nvkkhwydd*ii

  4. Dicty_cDB: SLA826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLA826 (Link to dictyBase) - - - Contig-U16455-1 SLA826Z (Link... to Original site) - - SLA826Z 681 - - - - Show SLA826 Library SL (Link to library) Clone ID SLA826 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLA8-B/SLA826Q.Seq.d/ Representative seq. ID SLA82...6Z (Link to Original site) Representative DNA sequence >SLA826 (SLA826Q) /CSM/SL/SLA8-B/SLA826Q.Seq.d/ XXXXX...ence update 1998. 3.20 Translated Amino Acid sequence ---IGGIGTVPVGRVETGIIKPGMVVTFAPAGLSTEVKSVEMHHEQLPEARPGD

  5. Dicty_cDB: CFD826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CF (Link to library) CFD826 (Link to dictyBase) - - - Contig-U14187-1 CFD826P (Link to Original site) CFD...826F 546 CFD826Z 289 CFD826P 835 - - Show CFD826 Library CF (Link to library) Clone ID CFD... URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CF/CFD8-B/CFD826Q.Seq.d/ Representative seq. ID CFD...826P (Link to Original site) Representative DNA sequence >CFD826 (CFD826Q) /CSM/CF/CFD8-B/CFD8...quences producing significant alignments: (bits) Value CFD826 (CFD826Q) /CSM/CF/CFD8-B/CFD826Q.Seq.d/ 985 0.

  6. Dicty_cDB: AFM826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AF (Link to library) AFM826 (Link to dictyBase) - - - - - (Link to Original site) - - AFM...826Z 165 - - - - Show AFM826 Library AF (Link to library) Clone ID AFM826 (Link to dictyBase) Atlas ID... - NBRP ID - dictyBase ID - Link to Contig - Original site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/AF/AFM8-B/AFM...826Q.Seq.d/ Representative seq. ID - (Link to Original site) Representative DNA sequence >AFM...826 (AFM826Q) /CSM/AF/AFM8-B/AFM826Q.Seq.d/ XXXXXXXXXXTAAATCAATTCCAGATTTATTGGAATTGGATCATC

  7. 21 CFR 172.826 - Sodium stearyl fumarate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Sodium stearyl fumarate. 172.826 Section 172.826 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Multipurpose Additives § 172.826...

  8. 33 CFR 154.826 - Vapor compressors and blowers.

    Science.gov (United States)

    2010-07-01

    ... system acceptable to the Commandant (CG-522). (b) If a reciprocating or screw-type compressor handles... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Vapor compressors and blowers....826 Vapor compressors and blowers. (a) Each inlet and outlet to a compressor or blower which...

  9. Clinical analysis on 826 cases of vitiligo%白癜风826例临床分析

    Institute of Scientific and Technical Information of China (English)

    鲍迎秋; 傅裕; 常建民

    2009-01-01

    对1998年至2008年我院白癜风门诊就诊的826例患者的临床资料做回顾性分析.结果 示其发病时间主要在青少年期;有阳性家族史者占20.6%(170例),一、二级亲属共患率分别为44.1%(75例)和41.2%(70例),高于三级亲属;家族史阳性患者的平均发病年龄(25±16)岁,早于家族史阴性患者[(28±17)岁],两者差异有统计学意义(t=1.97,P<0.05).合并自身免疫性疾病的患者67例,占8.1%;儿童白癜风患者比其他年龄患者更易发生同形反应和出现晕痣(P<0.05).%We retrospectively reviewed the clinical data of 826 cases with vitiligo treated in Beijing Hospital from 1998 to 2008. Most of patients present vitiligo in early age;20. 6% patients had positive family history. There were 44. 12 %, 41.18% and 10. 00 % of patients with vitiligo in their first, second and third degree relatives, respectively. Patients with family history had an earlier onset than those without a family history ( t = 1.97, P < 0. 05 ). Vitiligo vulgaris was found in 91.40 % patients. The most common affected site was head and face (31.5%) ;8. 1% of the patients was associated with other autoimmune diseases, including thyroid diseases, diabetes. There were more females than males in patients aged below 14. The child patients were more likely to present with Koebner' sign and halo nevus than the elder ones (P<0.05).

  10. 38 CFR 8.26 - Renewal of National Service Life Insurance on the 5-year level premium term plan.

    Science.gov (United States)

    2010-07-01

    ... Service Life Insurance on the 5-year level premium term plan. 8.26 Section 8.26 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS NATIONAL SERVICE LIFE INSURANCE Renewal of Term Insurance § 8.26 Renewal of National Service Life Insurance on the 5-year level premium term plan. (a)...

  11. 多功能酸洗缓蚀剂Lan-926与Lan-826缓蚀性能的对比研究%The comparative study of corrosion inhibitive effect between pickling inhibitor Lan- 926 and Lan- 826

    Institute of Scientific and Technical Information of China (English)

    孙小红

    2006-01-01

    多功能酸洗缓蚀剂Lan-926是在Lan-826基础上的更新配方.研究了在不同酸液温度、不同酸浓度、不同缓蚀剂添加量下,将Lan-926与Lan-826进行缓蚀性能对比实验.结果表明:Lan-926与Lan-826具有同样优异的缓蚀性能,且Lan-926生产成本仅为Lan-826的2/3.

  12. 26 CFR 1.826-1 - Election by reciprocal underwriters and interinsurers.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis of Perpetual Policies Or Premium Deposits) § 1.826-1 Election by reciprocal underwriters and interinsurers....

  13. 26 CFR 1.826-2 - Special rules applicable to electing reciprocals.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis of Perpetual Policies Or Premium Deposits) § 1.826-2 Special rules applicable to electing reciprocals....

  14. 26 CFR 1.826-3 - Attorney-in-fact of electing reciprocals.

    Science.gov (United States)

    2010-04-01

    ...) INCOME TAX (CONTINUED) INCOME TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis of Perpetual Policies Or Premium Deposits) § 1.826-3 Attorney-in-fact of electing reciprocals. (a) Manner of...

  15. URANS simulations of separated flow with stall cells over an NREL S826 airfoil

    DEFF Research Database (Denmark)

    Sarlak Chivaee, Hamid; Nishino, T.; Sørensen, Jens Nørkær

    2016-01-01

    A series of wind tunnel measurements and oil flow visualization was recently carried out at the Technical University of Denmark in order to investigate flow characteristics over a 14% thick NREL S826 airfoil at low Reynolds numbers. This paper aims at presenting numerical simulations of the same...... airfoil using unsteady Reynolds-averaged Navier-Stokes (URANS) approach. Results of the simulations are demonstrated in terms of mean flow velocity, lift and drag, as well as pressure distribution, and validated against available experimental data. The simulations are carried out with a wide computational...

  16. Throat Foreign Body Removal Surgery in 826 Cases under Video Laryngoscope of Straight Pipe%直管电子喉镜下咽喉异物取出术826例临床分析

    Institute of Scientific and Technical Information of China (English)

    杨晓红; 倪宝良; 钮燕; 师克忠

    2011-01-01

    目的 探讨直管电子喉镜下钳取咽喉异物的应用价值.方法 回顾性分析利用storz直管电子喉镜经口进路对门诊咽喉部异物及怀疑有咽喉部异物患者826例的临床资料.结果 826例患者中802例发现有异物,并在镜下成功取出;24例未见异物的检查结果为咽喉部粘膜充血或粘膜溃疡,其中有7例见小血肿形成,经抗炎治疗1周后异物感症状消失,复查均未见异物遗留.结论 经口进路在直管电子喉镜下探查或取出咽喉部异物具有成功率高、视野清晰、安全准确、病人痛苦少、简便快捷、无创等优点,值得推广应用.%Objective To investigate the application value of the throat foreign body removal with forcep under the video laryngoscope of straight pipe. Method We retrospectively analyzed the clinical data of 826 patients with confirmed or suspected throat foreign bodies who received removal surgery throat foreign bodies under storz video laryngoscope of straight pipe through the mouth. Results Among 826 patients, throat foreign bodies were found in 802 patients and and successfully removed under the video laryngoscope of straight pipe; no foreign bodies except throat mucosal congestion or mucous membrane ulcers were found in 24 patients, including 7 patients with small hematoma. A week later the foreign body sensation of symptoms disappeared by anti-inflammatory treatment. Review showed no foreign body left behind in the throat. Conclusions Exploration or removal of throat foreign bodies under video laryngoscope of straight pipe through oral route has many advantages such as high success rate, clear vision, ecurity, accuracy, less pain, easy and noninvasive operation. This technology should be widely applied.

  17. Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis

    DEFF Research Database (Denmark)

    Moore, Craig S.; Earl, Nathalie; Frenette, Richard;

    2006-01-01

    Administration of phosphodiesterase 4 (PDE4) inhibitors suppresses the pathogenesis associated with experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). In the present study, we compared the effects of rolipram and 4-[2-(3,4-bis-difluoromethoxyphenyl)-2...... observed. Only L-826,141 at a dose of 30 mg/kg p.o. significantly decreased the clinical severity of EAE compared with vehicle controls. Immunohistochemical detection of the neuronal activity marker Fos confirmed that L-826,141 did not reach concentrations in the central nervous system sufficient...... demonstrate that peripheral PDE4 inhibition, produced by L-826,141, prevents the progression of EAE after the first onset of clinical signs, and suggest that similar compounds may have clinical efficacy in the treatment of MS....

  18. Comparison of the amount of bioaccessible fumonisin B1 and B2 in maize and rice inoculated with Fusarium verticillioides (MRC 826) and determined by in vitro digestion-preliminary results.

    Science.gov (United States)

    Szabó-Fodor, J; Bors, I; Szabó, A; Kovács, M

    2016-08-01

    In this study the occurrence of hidden fumonisin B1 (FB1) and fumonisin B2 (FB2) was analysed, on two cereal substrates (maize and rice), inoculated with Fusarium verticillioides (MRC 826), in order to determine the ratio of hidden FB1 and FB2. Two parallel methods were applied: an in vitro human digestion sample pre-treatment and the routine extraction procedure, in both cases with subsequent LC-MS analysis. It was found that all samples showed higher concentration of total fumonisin B1 after digestion, as compared to that of free fumonisin analysed only after extraction. The percentage of the hidden form by maize was 18.8 % (±2.4) for FB1 and 36.8 % (±3.8) for FB2, while for rice it was 32.3 % (±11.3) and 58.0 (±6.8), respectively, expressed as the proportion to total fumonisin B1, for the total dataset. Significant differences were found in the FB1 and FB2 concentration measured after the different digestion phases (saliva, gastric and duodenal) in case of both matrixes. The results are useful for human risk assessment, since both humans and animals may be exposed to markedly higher toxin load, as determined merely by conventional analytical methods. PMID:27364334

  19. 26 CFR 1.826-7 - Examples.

    Science.gov (United States)

    2010-04-01

    ... TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis of Perpetual Policies Or Premium Deposits) § 1... Underwriting gain 0 Mutual insurance company taxable income 0 Unused loss 22 Credit or refund for taxes paid...

  20. Dicty_cDB: SSF826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LGGSMVKQPFAIGGSGSTYIYGYCDSKFKPKMTKDECIEFVQNSLALAMFRDGSSGGV IRLCIIDKNGVERKMIPGNNLPRFWEG*fsni*imiginhayniivkk*... IRLCIIDKNGVERKMIPGNNLPRFWEG*fsni*imiginhayniivkk*lkkn Frame C: ---li*vlllwq*nmmvvllwvqiqelplvhisqielqtklpqf

  1. Dicty_cDB: SFD826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available nserina genomic DNA c... 84 1e-14 BC162026_1( BC162026 |pid:none) Rattus norvegicus alveolar soft pa... 79 3... BC142388_1( BC142388 |pid:none) Bos taurus alveolar soft part sarc... 71 7e-11 AM270071_2( AM270071 |pid:no

  2. 26 CFR 1.826-6 - Credit or refund.

    Science.gov (United States)

    2010-04-01

    ...) INCOME TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis of Perpetual Policies Or Premium...

  3. 26 CFR 1.826-5 - Attribution of tax.

    Science.gov (United States)

    2010-04-01

    ...) INCOME TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis of Perpetual Policies Or Premium...

  4. 26 CFR 1.826-4 - Allocation of expenses.

    Science.gov (United States)

    2010-04-01

    ...) INCOME TAXES Mutual Insurance Companies (other Than Life and Certain Marine Insurance Companies and Other Than Fire Or Flood Insurance Companies Which Operate on Basis of Perpetual Policies Or Premium...

  5. Focal Chorus 826W特别版音箱

    Institute of Scientific and Technical Information of China (English)

    赵聪; 庄宏道(摄影)

    2012-01-01

    要说法国Focal音箱的代表作,无疑是新乌托邦系列。新乌托邦系列中的型号,无论是旗舰的Grande Utopia EM,还是稍小一号的Stella Utopia EM,都是同价位音箱中的佼佼者,

  6. 50 CFR 82.6 - Submission of proposals.

    Science.gov (United States)

    2010-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... grantees for changes, continuations, and supplements to approved grants must be submitted on the same...

  7. Dicty_cDB: AFJ826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available vsnflldtkrrllhfihlqvicipl liifghvivsltktvdsvhlnaimpvsmqfsrppmrsstvmntcfhyfiledpl*mfeie llitvdetmlimislcvicvs...ffifiiynlislif*wqn*k*lfil**ffvvvsnflldtkrrllhfihlqvicipl liifghvivsltktvdsvhlnaimpvsmqfsrppmrsstvmntcfhyfile

  8. Dicty_cDB: VFE826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available rmelon lambda zap library Citrullus lanatus cDNA clone WMLS336 5' similar to acetyl...of Vitis vinifera var. Chardonnay Vitis vinifera cDNA clone VVC055H06 5, mRNA sequence. 60 3e-08 2 AI563047 |AI563047.1 EST00171 wate

  9. Dicty_cDB: SLJ826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 033B22f, mRNA sequence. 50 0.023 1 CB290319 |CB290319.1 UCRCS01_01ag06_g1 Washington Navel orange cold acclimate... mRNA sequence. 50 0.023 1 CB290210 |CB290210.1 UCRCS01_01aa11_g1 Washington Navel orange cold acclimated fl

  10. Dicty_cDB: VFA826 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ne cLEW24B16 5' sequence, mRNA sequence. 50 0.051 1 AW737899 |AW737899.1 EST339326 tomato flower buds, anthesis, Cornell...57.1 EST259436 tomato susceptible, Cornell Lycopersicon esculentum cDNA clone cLES5P3, mRNA sequence. 50 0.0...51 1 BE354506 |BE354506.1 EST355849 tomato flower buds, anthesis, Cornell University Lycopersicon esculentum

  11. Melittin and the 8-26 fragment. Differences in ionophoric properties as measured by monolayer method.

    OpenAIRE

    Gevod, V S; Birdi, K. S.

    1984-01-01

    Melittin is a major (approximately 50%) protein component of bee venom. This peptide is an amphiphilic protein, because, while the amino acid residues 1-20 are predominantly hydrophobic (with the exception of Lys-7), residues 21-26 are hydrophilic. The binding properties to vesicles and lipid bilayers of melittin have provided much useful information regarding biological (hemolytic) activity (Habermann, E., 1972, Science [Wash. DC], 177:314-322). Recent studies have convincingly established t...

  12. 13 CFR 120.826 - Basic requirements for operating a CDC.

    Science.gov (United States)

    2010-01-01

    ... such loan, loan-related collateral or appraisal) and standards for work papers and supporting... accountant that is independent and experienced in auditing financial institutions. The audit must be.... The audit or review must be conducted by an independent certified public accountant who: (1)...

  13. Michigan Senate Bill 826: Replace Common Core with pre-2011 Massachusetts Standards

    Directory of Open Access Journals (Sweden)

    Sandra Stotsky

    2016-04-01

    Full Text Available Interested in academic standards and assessments proven to raise student achievement? You won’t get that from the Common Core Standards and their associated consortium tests, PARCC and SBAC. Despite the boisterous hype of higher, deeper, richer, more rigorous, and so on, there exists no valid evidence to support their claims of higher quality, achievement, or college readiness. There is a set of state standards and assessments, however, proven through actual experience to have raised academic achievement for students at all levels and in all curricular pathways: those used in Massachusetts from 2000 to 2011. So, why not use them? Such a proposal was recently proposed, and passed, by the Michigan Senate Education Policy Committee. Here, we provide links to Sandra Stotsky’s testimony before that committee, along with other relevant links. - See more at: http://nonpartisaneducation.org/Review/Resources/MichiganBill.htm

  14. Rethinking Lavoix's Attribution of the Dinar dated 210 AH/AD 825-826

    OpenAIRE

    Atef Mansour, M. Ramadan

    2016-01-01

    The paper aims at reconsidering a dinar attributed to the 'Abbasid caliph al- Ma’rnun (198-218 AH/AD 813-833), first published in 1887 by the French scholar H. Lavoix. Later on, this attribution was repeated, without questioning, by a number of scholars despite the fact that - at the beginning of the 20th century - the Sicilian numismatist B. Lagumina had noticed that the legends on the gold specimen in the BnF's coin cabinet were comparable to the silver issues of the revolt l...

  15. 77 FR 826 - Cantilever Capital, LLC and Cantilever Group, LLC; Notice of Application

    Science.gov (United States)

    2012-01-06

    ...; guidance on industry best practices; advice on planning, strategy and product development; geographic... comply with the Internal Revenue Code's diversification requirements for regulated investment...

  16. Thermal degradation of new and aged urethane foam and epon 826 epoxy.

    Energy Technology Data Exchange (ETDEWEB)

    Kruizenga, Alan Michael; Mills, Bernice E.

    2013-08-01

    Thermal desorption spectroscopy was used to monitor the decomposition as a function of temperature for the foam and epoxy as a function of temperature in the range of 60C to 170C. Samples were studied with one day holds at each of the studied temperatures. Both new (FoamN and EpoxyN) and aged (FoamP and EpoxyP) samples were studied. During these ~10 day experiments, the foam samples lost 11 to 13% of their weight and the EpoxyN lost 10% of its weight. The amount of weight lost was difficult to quantify for EpoxyP because of its inert filler. The onset of the appearance of organic degradation products from FoamP began at 110C. Similar products did not appear until 120C for FoamN, suggesting some effect of the previous decades of storage for FoamP. In the case of the epoxies, the corresponding temperatures were 120C for EpoxyP and 110C for EpoxyN. Suggestions for why the aged epoxy seems more stable than newer sample include the possibility of incomplete curing or differences in composition. Recommendation to limit use temperature to 90-100C for both epoxy and foam.

  17. 40 CFR 82.6 - Apportionment of baseline consumption allowances for class I controlled substances.

    Science.gov (United States)

    2010-07-01

    ... 12,466 Dow Chemical Company, USA 8,170,561 E.I. DuPont de Nemours & Co 26,537 Elf Atochem, N.A 41...,355 Dow Chemical Company, USA 125,200,200 E.I. DuPont de Nemours & Co 2 IBM 2,026 ICI Americas, Inc 14... 1986 are apportioned chemical-specific baseline consumption allowances as set forth in paragraphs...

  18. Desarmamento no Brasil: Lei 9.437/97 x Lei 10.826/03

    OpenAIRE

    Márcio Santos Aleixo; Guilherme Antônio Behr

    2015-01-01

    A segregação da sociedade brasileira, somada a histórica e farta disponibilidade de armas de fogo e munição, acarreta em elevados índices de criminalidade. Contudo, observa-se grande evolução na legislação brasileira relativa às armas de fogo visando restringir seu acesso, datando do início do século XVII aos dias atuais. Nesse sentido, o presente trabalho teve como objetivo discutir acerca do controle normativo das armas de fogo por parte do Estado, dando base para uma futura convalidação da...

  19. Aerodynamic behaviour of NREL S826 airfoil at Re=100,000

    DEFF Research Database (Denmark)

    Chivaee, Hamid Sarlak; Mikkelsen, Robert Flemming; Sarmast, Sasan;

    2014-01-01

    at Fluid Mechanics laboratory of the Technical University of Denmark (DTU). Lift coefficient is obtained from the forge gauge measurements while the drag is measured according to the integration of the wake profiles downstream of the airfoil. The pressure distribution is measured by a set of pressure taps......, there is a better agreement between the drag measurements and computations. It is concluded that LES computations are able to capture the lift and drag polars as well as the pressure distribution around the airfoil with an acceptable accuracy....

  20. Large-eddy simulations of a S826 airfoil with the Discontinuous Galerkin Method

    DEFF Research Database (Denmark)

    Frère, A.; Chivaee, Hamid Sarlak; Mikkelsen, Robert Flemming;

    2014-01-01

    experiment performed at the Technical University of Denmark. Chordwise pressure evolutions, integrated lift and drag forces are compared at Reynolds number 4.104 and angles of attack (AoA) 10 and 12 degrees. Important differences are observed between the simulations and the experiment. These differences are......, however, partially explained by the strong sensitivity to the tunnel environment. To overcome this source of error, the ArgoDG LES results are also compared to LES performed with the Finite Volume Method (FVM) code EllipSys3D, a well established wind turbine Computational Fluid Dynamics (CFD) code...

  1. Supplement: “Localization and Broadband Follow-up of the Gravitational-wave Transient GW150914” (2016, ApJL, 826, L13)

    Science.gov (United States)

    Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Barthelmy, S.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Behnke, B.; Bejger, M.; Bell, A. S.; Bell, C. J.; Berger, B. K.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Birney, R.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, G.; Bogan, C.; Bohe, A.; Bojtos, P.; Bond, C.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Bustillo, J. C.; Callister, T.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Diaz, J. C.; Casentini, C.; Caudill, S.; Cavagliá, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Baiardi, L. C.; Cerretani, G.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chen, H. Y.; Chen, Y.; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M., Jr.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. S.; Dattilo, V.; Dave, I.; Daveloza, H. P.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; DeBra, D.; Debreczeni, G.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dereli, H.; Dergachev, V.; DeRosa, R. T.; De Rosa, R.; DeSalvo, R.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Dojcinoski, G.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Engels, W.; Essick, R. C.; Etzel, T.; Evans, M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fournier, J.-D.; Franco, S.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H. A. G.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gatto, A.; Gaur, G.; Gehrels, N.; Gemme, G.; Gendre, B.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghosh, A.; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Castro, J. M. G.; Gopakumar, A.; Gordon, N. A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Graef, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.; Hall, B. R.; Hall, E. D.; Hammond, G.; Haney, M.; Hanke, M. M.

    2016-07-01

    This Supplement provides supporting material for Abbott et al. (2016a). We briefly summarize past electromagnetic (EM) follow-up efforts as well as the organization and policy of the current EM follow-up program. We compare the four probability sky maps produced for the gravitational-wave transient GW150914, and provide additional details of the EM follow-up observations that were performed in the different bands.

  2. Comment to the sentence of the provincial audience of Valencia nº. 949/2011 826 23-11-2011: No registration in the civil register of the born minors by means of gestation by replacement Comentario a la sentencia de la audiencia provincial de Valencia núm. 949/2011 826 23-11/2011: No inscripción en el registro civil de los menores nacidos mediante gestación por sustitución

    Directory of Open Access Journals (Sweden)

    Yvette Velarde D'Amil

    2012-12-01

    Full Text Available The Judgement of the Provincial Court of Valencia is, currently, the latest link in a series of events which main issues are the willingness for paternage, the freedom of the parties to choose, the technology of human assissted reproduction (surrogacy and the legal status of children born by international surrogacy arrangements and its possible conflict with mandatory Spanish laws and with a series of general legal principles consecrated in the Spanish Constitution, such as the normative hierarchy, the non-commerciality of human being, the respect for their dignity, and the protection of the superior welfare of the minor, among others.La Sentencia de la Audiencia Provincial de Valencia es de momento, el último eslabón de una serie de hechos que tienen como cuestión de fondo el anhelo de la paternidad, la autonomía de la voluntad de las partes, la técnica de reproducción humana asistida denominada gestación por sustitución y la situación jurídica de los niños nacidos mediante acuerdos internacionales de maternidad subrogada y su posible contradicción con leyes imperativas españolas y con una serie de principios generales del Derecho consagrados por la Constitución Española, como la jerarquía normativa, la no comercialidad de la persona humana, el respeto a su dignidad, y la protección del interés superior del menor, entre otros.

  3. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to rye fibre and changes in bowel function (ID 825), reduction of post-prandial glycaemic responses (ID 826) and maintenance of normal blood LDL-cholesterol

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to rye fibre and changes in bowel function, reduction of post-prandial glycaemic responses and maintenance of normal blood LDL-cholesterol concentrations. The scientific substantiation is based on the information provided by the Member States in the consolidated list of Article 13...

  4. Dicty_cDB: [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFB826 (Link to dictyBase) - - - Contig-U16584-1 VFB826F (Link... to Original site) VFB826F 430 - - - - - - Show VFB826 Library VF (Link to library) Clone ID VFB826 (Link to dict...yBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16584-1 Original site URL http://dict... (bits) Value N AC115577 |AC115577.2 Dictyostelium discoideum chromosome 2 map 4657875-4914984 strain AX4, c...vesicles of secretory system 4.0 %: endoplasmic reticulum >> prediction for VFB82

  5. Pop / Raul Saaremets

    Index Scriptorium Estoniae

    Saaremets, Raul

    2002-01-01

    Heliplaatidest Starsailor" Love is Here". Chicago Underground Quartet "Chicago Underground Quartet". Mower "Mower". Kim Wilde "The Very Best of". Mull Historical Society "Loss". Jill Scott "Experience: 826+"

  6. 33 CFR 156.170 - Equipment tests and inspections.

    Science.gov (United States)

    2010-07-01

    ... detonation arrester required by § 154.820, § 154.826(a), and § 154.828(a) of this chapter or 46 CFR 39.40-3(d), and each flame arrester required by § 154.826(a), § 154.828 (a) and (c) of this chapter has been....820(a) and § 154.824 (d) and (e) of this chapter or 46 CFR 39.40-3(a) is calibrated: (i) Within...

  7. (1) H-NMR relaxometric studies of interaction between apoptosis specific MRI paramagnetic contrast agents and micellar models of apoptotic cells.

    Science.gov (United States)

    Van Koninckxloo, Aurore; Henoumont, Céline; Laurent, Sophie; Muller, Robert N; Vander Elst, Luce

    2016-07-01

    (1) H-NMR was previously used to analyze the interaction between peptides (E3 and R826) selected by phage display to target apoptotic cells and phospholipidic models of these cells. In order to avoid the use of apoptotic cells and to obtain a fast evaluation of the efficiency of the potential MRI contrast agents obtained by grafting these peptides and their scramble analogs on a paramagnetic gadolinium complex, their proton relaxometric behavior was investigated in the presence of micelles mimicking healthy and apoptotic cells. Their preferential interaction with 1,2-dipalmitoyl-sn-glycero-3-phospho-l-serine micelles mimicking apoptotic cells as compared with 1,2-dipalmitoyl-sn-glycero-3-phosphocholine micelles modeling healthy cells was shown by nuclear magnetic relaxation dispersion profiles and the enhancement of the transverse proton relaxation rates at 60 MHz. The association constant values confirm the stronger interaction of the selected conjugated peptides (Ka Gd-PMN-E3(gadolinium 2,2',2'',2'''-[((4-carboxy)pyridine-2,6-diyl)bis(methylenenitrilo)]-tetrakis acetate) grafted with E3 peptide): 2.43 10(4)  m(-1) ; Ka Gd-DTPA-R826(gadolinium ((1-p-isothiocyanatobenzyl)-diethylenetriaminepentaacetate) grafted with R826 peptide): 2.91 10(4)  m(-1) ) as compared with their conjugated scrambles (Ka Gd-PMN-E3sc(gadolinium 2,2',2'',2'''-[((4-carboxy)pyridine-2,6-diyl)bis(methylenenitrilo)]-tetrakis acetate) grafted with E3 scramble peptide): 0.18 10(4)  m(-1) ; Ka Gd-DTPA-R826sc(gadolinium ((1-p-isothiocyanatobenzyl)-diethylenetriaminepentaacetate) grafted with R826 scramble peptide): 0.32 10(4)  m(-1) ) even if the conjugation of E3 and R826 seems to decrease their interaction. Copyright © 2015 John Wiley & Sons, Ltd. PMID:26647764

  8. 75 FR 65551 - Notice of Passenger Facility Charge (PFC) Approvals and Disapprovals

    Science.gov (United States)

    2010-10-25

    .../10 143,826,944 100,826,944 10/01/12 11/01/11 00-03-C-02-BIL, Billings, MT 09/16/10 5,163,262 3,278,253 10/01/05 04/01/04 05-04-C-01-BIL, Billings, MT 09/16/10 3,300,000 3,285,586 05/01/07 04/01/07 05... Hebert, Manager, Financial Analysis and Passenger Facility Charge Branch. BILLING CODE 4910-13-M...

  9. GETDB: 104325 [GETDB

    Lifescience Database Archive (English)

    Full Text Available 104325 Link to Original w[*]; P{GawB}NP2788 / CyO 38C6 Link to DGRC Genome Viewer: 10432...nstitute of Genetics. CyO Link to clone table - - 826 Link to cluster table 826 1 Request - - - - - - - - - - - - Show 10432...5 DGRC Number 104325 Link to Original Genotype w[*]; P{GawB}NP278...8 / CyO Insertion Site 38C6 Map Viewer Link to DGRC Genome Viewer: 104325 Related Genes CG10076 CG12617 CG18

  10. File list: His.Lng.10.macroH2A1.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Lng.10.macroH2A1.AllCell hg19 Histone macroH2A1 Lung SRX469060,SRX469058,SRX826...360 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Lng.10.macroH2A1.AllCell.bed ...

  11. File list: His.Lng.05.macroH2A1.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Lng.05.macroH2A1.AllCell hg19 Histone macroH2A1 Lung SRX469060,SRX469058,SRX826...360 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Lng.05.macroH2A1.AllCell.bed ...

  12. Making Their Voices Heard: A Partnership to Build Writing Skills through Empowerment, Imagination, and Scaffolded Supports

    Science.gov (United States)

    Varady, Ashley

    2015-01-01

    In San Francisco, a partnership between a K-8 school and a non-profit writing program helps students who are achieving below grade level find their voices and blossom into confident thinkers and writers. 826 Valencia is a non-profit organization dedicated to supporting under-resourced students ages six to eighteen with their creative and…

  13. File list: His.Lng.20.macroH2A1.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Lng.20.macroH2A1.AllCell hg19 Histone macroH2A1 Lung SRX469060,SRX469058,SRX826...360 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Lng.20.macroH2A1.AllCell.bed ...

  14. File list: His.Lng.50.macroH2A1.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Lng.50.macroH2A1.AllCell hg19 Histone macroH2A1 Lung SRX469060,SRX469058,SRX826...360 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Lng.50.macroH2A1.AllCell.bed ...

  15. The influence of near-bed hydrodynamic conditions on cold-water corals in the Viosca Knoll area, Gulf of Mexico

    NARCIS (Netherlands)

    Mienis, F.; Duineveld, G.C.A.; Davies, A.J.; Ross, S.W.; Seim, H.; Bane, J.; van Weering, T.C.E.

    2012-01-01

    Near-bed hydrodynamic conditions were recorded for almost one year in the Viosca Knoll area (lease block 826), one of the most well-developed cold-water coral habitats in the Gulf of Mexico. Here, a reef-like cold-water coral ecosystem, dominated by the coral Lophelia pertusa, resembles coral habita

  16. Can reduced stocking rates and natural forage utilization produce market sized catfish from fingerlings in one growing season

    Science.gov (United States)

    The purpose of this study was to determine the feasibility of growing marketable channel catfish Ictalurus punctatus from pond-run fingerlings (15.9 g/fish) using low stocking densities (7,413 or 14,826 fish/ha) and electrified bug lights to enhance natural forage available to fish. Even at low sto...

  17. Data of evolutionary structure change: 1CCTA-3D0NB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available ID> A 1CCTA VHWNT-KYGDF ...1CCTA-3D0NB 1CCT 3D0N A B ------WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHT...SIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 0 1CCTEEEEE-GG Hure> ATOM 933 CA VAL A 121 -11.826 4.712 15.895

  18. Data of evolutionary structure change: 1CCTA-3D0NA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available A 1CCTA VHWNT-KYGDF ...1CCTA-3D0NA 1CCT 3D0N A A ------WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHT...SIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH 0 1CCT...ure>EEEEE-GG Hure> ATOM 933 CA VAL A 121 -11.826 4.712 15

  19. Photochemical behavior of some p-styryistilbenes and related compounds: Spectral properties and photoisomerization in solution and in solid state

    OpenAIRE

    Zhu, FQ; Motoyoshiya, J; Nakamura, J.; Nishii, Y; Aoyama, H

    2006-01-01

    Author Posting. © The Authors (2006) This is the author's version of the work. It is posted here for personal use, not for redistribution. The definitive version was published in PHOTOCHEMISTRY AND PHOTOBIOLOGY, 82(6): 1645-1650. http://dx.doi.org/10.1562/2006-01-17-RA-780

  20. Assessing Student Writing on Tablets

    Science.gov (United States)

    Davis, Laurie Laughlin; Orr, Aline; Kong, Xiaojing; Lin, Chow-Hong

    2015-01-01

    There is increasing expectation that schools should be able to use tablets for a range of instructional and assessment purposes. This article considers the comparability of student writing on tablets and laptops to ensure that writing assessment is conducted in a way that is fair to all students. Data were collected from a sample of 826 students…

  1. Unigene BLAST: CBRC-BTAU-01-0137 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-BTAU-01-0137 gnl|UG|Bt#S39680806 LB0241.C21_H05 GC_BGC-24 Bos taurus cDNA clone IMAGE...:8631415 3', mRNA sequence /clone=IMAGE:8631415 /clone_end=3' /gb=EV708195 /gi=154485244 /ug=Bt.9663 /len=826 2e-60 65% ...

  2. Dicty_cDB: VSG887 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available nelnkkiikkyt nnkkk--- Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value ...mology vs DNA Score E Sequences producing significant alignments: (bits) Value N BH562562 |BH562562.1 BOGQE5...ate 2003. 8.26 Homology vs Protein Score E Sequences producing significant alignments: (bits) Value (Q645J3)

  3. Evaluation of the performance of the novel PapilloCheck HPV genotyping test by comparison with two other genotyping systems and the HC2 test

    DEFF Research Database (Denmark)

    Schopp, Betti; Holz, Barbara; Zago, Manola;

    2010-01-01

    The novel PapilloCheck genotyping test was compared with SPF10 PCR LiPav1 and PGMY09/11 on hybrid capture 2 (HC2)-pretested samples. From results of 826 cervical samples detection rates and kappa values for the tests were calculated using a HPV type consensus definition. With PapilloCheck HPV typ...

  4. The Micropolitics of Effective School-Based Leadership: Teachers' Perspectives.

    Science.gov (United States)

    Blase, Joseph

    1993-01-01

    Micropolitics is the use of formal and informal power by groups and individuals to achieve their goals in organizations. Article summarizes findings of study examining 1,200 teachers' perspectives on the everyday strategies that principals use to influence them. Data from 826 teachers describing open and effective principals suggest that such…

  5. Ultrasound effects.

    Science.gov (United States)

    Martin, A O

    1985-07-19

    In a listing of the new foreign associates of the National Academy of Sciences (News and Comment, 17 May, p. 826), the name of Pierre Chambon, Biochemistry, Institut de Chimie Biologique, Faculté de Médecine, Strasbourg, France, was inadvertently omitted.

  6. Quantitative magnetic resonance imaging in limb-girdle muscular dystrophy 2I

    DEFF Research Database (Denmark)

    Willis, Tracey A; Hollingsworth, Kieren G; Coombs, Anna;

    2014-01-01

    We conducted a prospective multinational study of muscle pathology using magnetic resonance imaging (MRI) in patients with limb-girdle muscular dystrophy 2I (LGMD2I). Thirty eight adult ambulant LGMD2I patients (19 male; 19 female) with genetically identical mutations (c.826C>A) in the fukutin-re...

  7. 76 FR 14562 - Federal Acquisition Regulation; Additional Requirements for Market Research

    Science.gov (United States)

    2011-03-16

    ... 52 RIN 9000-AL50 Federal Acquisition Regulation; Additional Requirements for Market Research AGENCY... interim rule amending the Federal Acquisition Regulation (FAR) to implement section 826, Market Research... items engages in market research as necessary before making purchases. DATES: Effective Date: April...

  8. Islamophobia Pre- and Post-September 11th, 2001

    Science.gov (United States)

    Sheridan, Lorraine P.

    2006-01-01

    Although much academic research has addressed racism, religious discrimination has been largely ignored. The current study investigates levels of self reported racial and religious discrimination in a sample of 222 British Muslims. Respondents indicate that following September 11th, 2001, levels of implicit or indirect discrimination rose by 82.6%…

  9. Measuring of block error rates in high-speed digital networks

    OpenAIRE

    Petr Ivaniga; Ludovit Mikus

    2006-01-01

    Error characteristics is a decisive factor for the digital networks transmission quality definition. The ITU – T G.826 and G.828 recommendations identify error parameters for high – speed digital networks in relation to G.821 recommendation. The paper describes the relations between individual error parameters and the error rate assuming that these are invariant in terms of time.

  10. Measuring of Block Error Rates in High-Speed Digital Networks

    Directory of Open Access Journals (Sweden)

    Petr Ivaniga

    2006-01-01

    Full Text Available Error characteristics is a decisive factor for the digital networks transmission quality definition. The ITU – TG.826 and G.828 recommendations identify error parameters for high – speed digital networks in relation to G.821 recommendation. The paper describes the relations between individual error parameters and the error rate assuming that theseare invariant in terms of time.

  11. 78 FR 22291 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-04-15

    ... Cathedral State Park, Aurora, 13000264 WYOMING Albany County Snow Train Rolling Stock, S. 1st & E. Sheridan... 696 Peachtree Street Apartments, 826 Peachtree St., Atlanta, 13000240 McDuffie County Lazenby, John... District, Roughly bounded by Mt. Vernon Rd., SE., 15th St., SE., S. & E. lot lines, Cedar Rapids,...

  12. 75 FR 54420 - Notice of Final Federal Agency Actions on US 290/Hempstead Corridor

    Science.gov (United States)

    2010-09-07

    .... 1251- 1342]; Land and Water Conservation Fund (LWCF) . 8. Executive Orders: E.O. 11990 Protection of...) in Harris County, Texas. Those actions grant licenses, permits, and approvals for the project..., District B (South), Federal Highway Administration, 300 East 8th Street, Room 826 Austin, Texas...

  13. Comparison of Roche MONITOR and Organon Teknika NucliSens assays to quantify human immunodeficiency virus type 1 RNA in cerebrospinal fluid.

    Science.gov (United States)

    Spearman, P; Fiscus, S A; Smith, R M; Shepard, R; Johnson, B; Nicotera, J; Harris, V L; Clough, L A; McKinsey, J; Haas, D W

    2001-04-01

    We compared Roche MONITOR and Organon Teknika NucliSens assays for human immunodeficiency virus type 1 (HIV-1) RNA in cerebrospinal fluid (CSF). Results of 282 assays were highly correlated (r = 0.826), with MONITOR values being 0.29 +/- 0.4 log(10) copies/ml (mean +/- standard deviation) values. Both assays can reliably quantify HIV-1 RNA in CSF.

  14. 77 FR 6760 - Rules of Practice in Air Safety Proceedings; Rules Implementing the Equal Access to Justice Act...

    Science.gov (United States)

    2012-02-09

    ... authority to issue emergency orders too frequently and in an unfair manner. The commenter urges the NTSB to... concerning the NTSB procedural rules codified at 49 CFR parts 821 and 826. 75 FR 80452. The NTSB specifically sought comments concerning the standard of review for emergency determinations, discovery and...

  15. Two-Dimensional Fourier Cosine Series Expansion Method for Pricing Financial Options

    NARCIS (Netherlands)

    Ruijter, M.J.; Oosterlee, C.W.

    2012-01-01

    The COS method for pricing European and Bermudan options with one underlying asset was developed in [F. Fang and C. W. Oosterlee, SIAM J. Sci. Comput., 31 (2008), pp. 826--848] and [F. Fang and C. W. Oosterlee, Numer. Math., 114 (2009), pp. 27--62]. In this paper, we extend the method to higher dime

  16. Examining Education and Newsroom Work Experience as Predictors of Communication Students' Perceptions of Journalism Ethics

    Science.gov (United States)

    Detenber, Benjamin H.; Cenite, Mark; Malik, Shelly; Neo, Rachel L.

    2012-01-01

    This study examines education and work experience in newsrooms as predictors of ethical perceptions among communication undergraduates at a large Singaporean university (N = 826). Results indicate that education is associated with ethical ideologies, perceived importance of journalism ethics codes, justifiability of using contentious news…

  17. Self-monitoring of lower leg skin temperature: accuracy of self-reported data and adherence to a cooling protocol for the prevention of venous leg ulcers

    Directory of Open Access Journals (Sweden)

    Kelechi TJ

    2015-12-01

    Full Text Available Teresa J Kelechi, Mohan Madisetti, Martina Mueller, Mary Dooley, Margaret Prentice College of Nursing, Medical University of South Carolina, Charleston, SC, USA Background: For intervention studies that require the use of participant self-reports, the quality and accuracy of recorded data and variability in participant adherence rates to the treatment can cause significant outcome bias.Purpose: To assess the quality and accuracy of participant documentation of daily self-monitoring of leg skin temperature, adherence to a graduated cooling treatment protocol to prevent venous leg ulcers, and the potential for bias in treatment effect in a randomized controlled trial that included a population with chronic venous disease.Methods: Individuals were randomized to a leg cooling intervention or placebo treatment group to daily self-monitor and record lower leg skin temperature over a 9-month period on monthly paper study logs. Returned study logs for the first 100 completed participants (n=54 cooling intervention, n=46 control were reviewed for quality and accuracy. Adherence was determined from evaluating the accuracy of participant documentation. To examine potential outcome bias in treatment effect, mean between group and within group comparisons of the before and after treatment differences were conducted using an intention-to-treat (ITT versus a modified intention-to-treat (mITT analysis approach with an 85% accuracy cut-off rate. Data were collected in 2011–2014.Results: Of the expected 900 study logs, 91.8% (826/900 were returned and 8.2% (74/900 were not. Non-mutually exclusive main error types in returned documentation included: 59.2% (489/826 white-outs, cross-off and/or overwrites, 34.9% (288/826 entries omitted, 29.4% (243/826 no performance of daily self-monitoring, 28.7% (237/826 no performance of the treatment intervention per the prescribed protocol regime, 26.8% (221/826 extraneous data, 8.6% (71/826 suspected fabrication, and 7

  18. Isolation and characterization of microsatellite loci in the whale shark (Rhincodon typus)

    OpenAIRE

    Ramírez-Macías, Deni; Shaw, Kristine; Ward, Rocky; Galván Magaña, Felipe; Vázquez-Juárez, Ricardo

    2009-01-01

    In preparation for a study on population structure of the whale shark (Rhincodon typus), nine species-specific polymorphic microsatellite DNA markers were developed. An inicial screening of 50 individuals from Holbox Island, Mexico found all nine loci to be polymorphic, with two to 17 alleles observed per locus. Observed and expected heterozygosity per locus ranged from 0.200 to 0.826 and from 0.213 to 0.857, respectively. Neither statistically significant deviations from Hardy–Weinberg expec...

  19. Alkyl polyglycoside/1-naphthol formulations. A case study of surfactant enhanced oil recovery

    Energy Technology Data Exchange (ETDEWEB)

    Iglauer, Stefan; Wu, Yongfu; Shuler, Patrick; Tang, Yongchun [California Institute of Technology, Covina, CA (United States). Div. of Chemistry and Chemical Engineering; Goddard, William A. III [California Institute of Technology, Pasadena, CA (United States). Div. of Chemistry and Chemical Engineering

    2011-03-15

    We present a case study of surfactant enhanced oil recovery using Alkyl polyglucoside/1-naphthol formulations. Alkyl polyglucosides are a green, non-toxic and renewable surfactant class synthesized out of agricultural raw materials. We measured interfacial tensions versus n-octane and viscosities of these formulations and conducted one coreflood enhanced oil recovery (EOR) experiment where we recovered 82.6 % of initial oil in place demonstrating that these formulations are efficient EOR agents. (orig.)

  20. Complete genome sequences of three strains of coxsackievirus a7.

    Science.gov (United States)

    Ylä-Pelto, Jani; Koskinen, Satu; Karelehto, Eveliina; Sittig, Eleonora; Roivainen, Merja; Hyypiä, Timo; Susi, Petri

    2013-04-11

    Genomes of three strains (Parker, USSR, and 275/58) of coxsackievirus A7 (CV-A7) were amplified by the long reverse transcription (RT)-PCR method and sequenced. While the sequences of Parker and USSR were identical, the similarities of 275/58 to the CV-A7 reference sequence, accession no. AY421765, were 82.6% and 96.2% for nucleotides and amino acids, respectively.

  1. Evaluation of IgG anti-toxoplasma avidity and polymerase chain reaction in the postnatal diagnosis of congenital toxoplasmosis.

    Science.gov (United States)

    Torres, Elizabeth; Rivera, Raul; Cardona, Nestor; Sanchez, Victor; Lora, Fabiana; Gómez-Marín, Jorge Enrique

    2013-06-01

    Confirmatory tests for congenital toxoplasmosis were evaluated in 23 infected and 31 uninfected newborns. Conventional polymerase chain reaction was better than real-time polymerase chain reaction, but did not identify additional cases. Avidity tests added 2 new cases that were not identified by other criteria. Overall sensitivity was 82.6%. Avidity assay, but not polymerase chain reaction, increased the sensitivity of confirmatory assays in congenital toxoplasmosis.

  2. Hyper abundant mesopredators and bird extinction in an Atlantic forest island

    OpenAIRE

    Mauro Galetti; Ricardo S. Bovendorp; Fadini, Rodrigo F.; Carlos O. A. Gussoni; Marcos Rodrigues; Ariane D. Alvarez; Guimarães Jr., Paulo R.; Kaiser Alves

    2009-01-01

    Islands can serve as model systems for understanding how biological invasions affect native species. Here we examine the negative effects of mesopredator mammals on bird richness at Anchieta Island, an 826 ha offshore island in the coast of Brazil. Anchieta Island has the highest density of mammals of the entire Atlantic forest, especially nest predators such as marmosets and coatis, introduced more than 20 years ago. This indiscriminate introduction of mammals may have affected directly the ...

  3. Shopping online and/or in-store? A structural equation model of the relationships between e-shopping and in-store shopping

    OpenAIRE

    Farag, Sendy; Schwanen, Tim; Dijst, Martin

    2005-01-01

    Searching product information or buying goods online is becoming increasingly popular and could affect shopping trips. However, the relationship between e-shopping and in-store shopping is currently unclear. The aim of this study is to investigate empirically how the frequencies of online searching, online buying, and non-daily shopping trips relate to each other, after controlling for sociodemographic, land use, behavioral, and attitudinal characteristics. Data were collected from 826 respon...

  4. Ureteral Stent Insertion in the Management of Renal Colic during Pregnancy

    OpenAIRE

    Choi, Chang Il; Yu, Young Dong; Park, Dong Soo

    2016-01-01

    To determine an optimal invasive intervention for renal colic patients during pregnancy after conservative treatments have been found to be unhelpful. Among the available invasive interventions, we investigated the reliability of a ureteral stent insertion, which is considered the least invasive intervention during pregnancy. Between June 2006 and February 2015, a total of 826 pregnant patients came to the emergency room or urology outpatient department, and 39 of these patients had renal col...

  5. The impact of a supplementary medication review and counselling service within the oncology outpatient setting

    OpenAIRE

    Read, H.; Ladds, S; Rhodes, B.; Brown, D.; Portlock, J.

    2007-01-01

    The impact on the care of breast cancer patients, of a pharmacy technician-led medication review and counselling clinic, provided in an outpatient setting, was investigated using a controlled randomised study. Compared to the controls, clinic patients showed a significantly improved level of understanding of their chemotherapy support medication (95% CI for difference in mean knowledge rating scores=2.165–2.826, P

  6. Identification of novel exons and transcribed regions by chimpanzee transcriptome sequencing

    OpenAIRE

    Wetterbom, Anna; Ameur, Adam; Feuk, Lars; Gyllensten, Ulf; Cavelier, Lucia

    2010-01-01

    Background We profile the chimpanzee transcriptome by using deep sequencing of cDNA from brain and liver, aiming to quantify expression of known genes and to identify novel transcribed regions. Results Using stringent criteria for transcription, we identify 12,843 expressed genes, with a majority being found in both tissues. We further identify 9,826 novel transcribed regions that are not overlapping with annotated exons, mRNAs or ESTs. Over 80% of the novel transcribed regions map within or ...

  7. The Direct and Interactive Effects of Neuroticism and Life Stress on the Severity and Longitudinal Course of Depressive Symptoms

    OpenAIRE

    Brown, Timothy A.; Rosellini, Anthony J.

    2011-01-01

    The direct and interactive effects of neuroticism and stressful life events (chronic and episodic stressors) on the severity and temporal course of depression symptoms were examined in 826 outpatients with mood and anxiety disorders, assessed on three occasions over a one-year period (intake, 6- and 12-month follow-ups). Neuroticism, chronic stress, and episodic stress were uniquely associated with intake depression symptom severity. A significant interaction effect indicated that the strengt...

  8. Socioeconomic and Ecological Factors Influencing Aedes aegypti Prevalence, Abundance, and Distribution in Dhaka, Bangladesh

    OpenAIRE

    Dhar-Chowdhury, Parnali; Haque, C. Emdad; Lindsay, Robbin; Hossain, Shakhawat

    2016-01-01

    This study examined household risk factors and prevalence, abundance, and distribution of immature Aedes aegypti and Aedes albopictus, and their association with socioeconomic and ecological factors at urban zonal and household levels in the city of Dhaka, Bangladesh. During the 2011 monsoon, 826 households in 12 randomly selected administrative wards were surveyed for vector mosquitoes. Results revealed that the abundance and distribution of immature Ae. aegypti and Ae. albopictus, and pupae...

  9. Randomized Comparison of Linezolid (PNU-100766) versus Oxacillin-Dicloxacillin for Treatment of Complicated Skin and Soft Tissue Infections

    OpenAIRE

    Stevens, Dennis L.; Smith, Leon G.; Bruss, Jon B.; McConnell-Martin, Maureen A.; Duvall, Sue E.; Todd, Wesley Mark; Hafkin, Barry

    2000-01-01

    This randomized, double-blind, multicenter trial compared the efficacy and safety of linezolid, an oxazolidinone, with those of oxacillin-dicloxacillin in patients with complicated skin and soft tissue infections. A total of 826 hospitalized adult patients were randomized to receive linezolid (600 mg intravenously [i.v.]) every 12 h or oxacillin (2 g i.v.) every 6 h; following sufficient clinical improvement, patients were switched to the respective oral agents (linezolid [600 mg orally] ever...

  10. STRUCTURES OF A PAIR OF DIASTEREOMERIC SALTS OF EPHEDRINE AND FLUORO-SUBSTITUTED CYCLIC PHOSPHORIC-ACID

    NARCIS (Netherlands)

    SLOT, HJB; LEUSEN, FJJ; VANDERHAEST, AD; VANBOLHUIS, F

    1992-01-01

    (1) Salt of (S)-(-)-5,5-dimethyl-4-omicron-fluorophenyl-2-hydroxy-1,3,2-dioxaphosphorinane 2-oxide and (1S,2R)-(+)-alpha-[(1-methylamino)ethyl]-benzyl alcohol, (+)-C10H16NO+.(-)-C11H13FO4P-, M(r) = 425.436, monoclinic, P2(1), a = 10.122 (1), b = 7.826 (1), c = 13.715 (1) angstrom, beta = 92.99 (1)-d

  11. Can Artificial Neural Networks be Applied in Seismic Predicition? Preliminary Analysis Applying Radial Topology. Case: Mexico

    OpenAIRE

    Mota-Hernandez, Cinthya; Esquivel-Rodriguez, Luis; Alvarado-Corona, Rafael

    2014-01-01

    Tectonic earthquakes of high magnitude can cause considerable losses in terms of human lives, economic and infrastructure, among others. According to an evaluation published by the U.S. Geological Survey, 30 is the number of earthquakes which have greatly impacted Mexico from the end of the XIX century to this one. Based upon data from the National Seismological Service, on the period between January 1, 2006 and May 1, 2013 there have occurred 5,826 earthquakes which magnitude has been greate...

  12. Separation and purification of epigallocatechin-3-gallate (EGCG) from green tea using combined macroporous resin and polyamide column chromatography.

    Science.gov (United States)

    Jin, Xin; Liu, Mingyan; Chen, Zaixing; Mao, Ruikun; Xiao, Qinghuan; Gao, Hua; Wei, Minjie

    2015-10-01

    Epigallocatechin-3-gallate (EGCG) is a major bioactive ingredient of green tea that produces beneficial neuroprotective effects. In this paper, to optimize the EGCG enrichment, thirteen macroporous resins with different chemical and physical properties were systemically evaluated. Among the thirteen tested resins, the H-bond resin HPD826 exhibited best adsorption/desorption capabilities and desorption ratio, as well as weakest affinity for caffeine. The absorption of EGCG on the HPD826 resin followed the pseudo-second-order kinetics and Langmuir isotherm model. The separation parameters of EGCG were optimized by dynamic adsorption/desorption experiments with the HPD826 resin column. Under the optimal condition, the content of EGCG in the 30% ethanol eluent increased by 5.8-fold from 7.7% to 44.6%, with the recovery yield of 72.1%. After further purification on a polyamide column, EGCG with 74.8% purity was obtained in the 40-50% ethanol fraction with a recovery rate of 88.4%. In addition, EGCG with 95.1% purity could be easily obtained after one-step crystallization in distilled water. Our study suggests that the combined macroporous resin and polyamide column chromatography is a simple method for large-scale separation and purification of EGCG from natural plants for food and pharmaceutical applications.

  13. Separation and purification of epigallocatechin-3-gallate (EGCG) from green tea using combined macroporous resin and polyamide column chromatography.

    Science.gov (United States)

    Jin, Xin; Liu, Mingyan; Chen, Zaixing; Mao, Ruikun; Xiao, Qinghuan; Gao, Hua; Wei, Minjie

    2015-10-01

    Epigallocatechin-3-gallate (EGCG) is a major bioactive ingredient of green tea that produces beneficial neuroprotective effects. In this paper, to optimize the EGCG enrichment, thirteen macroporous resins with different chemical and physical properties were systemically evaluated. Among the thirteen tested resins, the H-bond resin HPD826 exhibited best adsorption/desorption capabilities and desorption ratio, as well as weakest affinity for caffeine. The absorption of EGCG on the HPD826 resin followed the pseudo-second-order kinetics and Langmuir isotherm model. The separation parameters of EGCG were optimized by dynamic adsorption/desorption experiments with the HPD826 resin column. Under the optimal condition, the content of EGCG in the 30% ethanol eluent increased by 5.8-fold from 7.7% to 44.6%, with the recovery yield of 72.1%. After further purification on a polyamide column, EGCG with 74.8% purity was obtained in the 40-50% ethanol fraction with a recovery rate of 88.4%. In addition, EGCG with 95.1% purity could be easily obtained after one-step crystallization in distilled water. Our study suggests that the combined macroporous resin and polyamide column chromatography is a simple method for large-scale separation and purification of EGCG from natural plants for food and pharmaceutical applications. PMID:26319304

  14. Impeller Submergence Depth for Stirred Tanks

    Directory of Open Access Journals (Sweden)

    Thiyam T. Devi

    2011-11-01

    Full Text Available Impeller submergence governs the performance of mixing tanks employed in oxygen transfer operation. Present work experimentally investigates the effect of impeller submergence depths on oxygen transfer and corresponding power consumption. It has been found that at higher range of impeller submergence, mixing tanks consume less power and gives higher values of oxygen transfer coefficient. Optimal range of submergence depth is 0.7 to 0.9 times the impeller diameter. Copyright ©2011 BCREC UNDIP. All rights reserved.(Received: 4th March 2011; Revised: 12nd July 2011; Accepted: 14th July 2011[How to Cite: T.T. Devi, A.P. Sinha, M. Thakre, and B. Kumar. (2011. Impeller Submergence Depth for Stirred Tanks. Bulletin of Chemical Reaction Engineering & Catalysis, 6 (2: 123-128. doi:10.9767/bcrec.6.2.826.123-128][How to Link / DOI: http://dx.doi.org/10.9767/bcrec.6.2.826.123-128 || or local: http://ejournal.undip.ac.id/index.php/bcrec/article/view/826] | View in 

  15. 西安地区女性生殖道NUC感染动态研究

    Institute of Scientific and Technical Information of China (English)

    金春子; 王绮云; 李萍; 邵明明; 贾卉

    2001-01-01

    本研究采用PCR法对1998年和1999年间我院拟诊为女性生殖道感染的826例患者阴道分泌物同步扩增特异性NUC-DNA,对其结果进行动态分析.其结果NG-DNA阳性率为19.95%(165/826),UU-DNA阳性率为28.45%(235/826),CT-DNA阳性率为10.53%(87/826),NUC总阳性率为46.97%(388/826).首先,把患者按不同年份分为2组后,比较各项检测结果,其结果1999年的NG、UU、NUC总阳性率较1998年高,有显著性差异(P<0.05);再次,把患者按不同月份分为12个组,比较其结果,女性生殖道NUC感染与季节有一定的关系.即NG感染夏、秋季明显于冬、春季(P<0.05);UU感染率冬季显著高于其它3个季节(P<0.05);CT感染率冬季较其它季节高,较夏季有显著性差异(P<0.05),而较春、秋季无显著性差异.NUC混合感染率也较高,共92例,NUC总阳性数的23.71%,混合感染多发生于淋菌感染的高发季节.随着女性生殖道UU感染的升高,NUC母婴传播对胎儿、新生儿威胁也大,应引起足够的重视,这对优生工作有重要的意义.

  16. Culture-independent characterization of bacterial communities associated with the cold-water coral Lophelia pertusa in the northeastern Gulf of Mexico

    Science.gov (United States)

    Kellogg, C.A.; Lisle, J.T.; Galkiewicz, J.P.

    2009-01-01

    Bacteria are recognized as an important part of the total biology of shallow-water corals. Studies of shallow-water corals suggest that associated bacteria may benefit the corals by cycling carbon, fixing nitrogen, chelating iron, and producing antibiotics that protect the coral from other microbes. Cold-water or deep-sea corals have a fundamentally different ecology due to their adaptation to cold, dark, high-pressure environments and as such have novel microbiota. The goal of this study was to characterize the microbial associates of Lophelia pertusa in the northeastern Gulf of Mexico. This is the first study to collect the coral samples in individual insulated containers and to preserve coral samples at depth in an effort to minimize thermal shock and evaluate the effects of environmental gradients on the microbial diversity of samples. Molecular analysis of bacterial diversity showed a marked difference between the two study sites, Viosca Knoll 906/862 (VK906/862) and Viosca Knoll 826 (VK826). The bacterial communities from VK826 were dominated by a variety of unknown mycoplasmal members of the Tenericutes and Bacteroidetes, whereas the libraries from VK906/862 were dominated by members of the Proteobacteria. In addition to novel sequences, the 16S rRNA gene clone libraries revealed many bacterial sequences in common between Gulf of Mexico Lophelia corals and Norwegian fjord Lophelia corals, as well as shallow-water corals. Two Lophelia-specific bacterial groups were identified: a cluster of gammaproteobacteria related to sulfide-oxidizing gill symbionts of seep clams and a group of Mycoplasma spp. The presence of these groups in both Gulf and Norwegian Lophelia corals indicates that in spite of the geographic heterogeneity observed in Lophelia-associated bacterial communities, there are Lophelia-specific microbes. Copyright ?? 2009, American Society for Microbiology. All Rights Reserved.

  17. Study on the polarity, solubility, and stacking characteristics of asphaltenes

    KAUST Repository

    Zhang, Long-li

    2014-07-01

    The structure and transformation of fused aromatic ring system in asphaltenes play an important role in the character of asphaltenes, and in step affect the properties of heavy oils. Polarity, solubility and structural characteristics of asphaltenes derived from Tahe atmospheric residue (THAR) and Tuo-826 heavy crude oil (Tuo-826) were analyzed for study of their internal relationship. A fractionation method was used to separate the asphaltenes into four sub-fractions, based on their solubility in the mixed solvent, for the study of different structural and physical-chemical properties, such as polarity, solubility, morphology, stacking characteristics, and mean structural parameters. Transmission electron microscope (TEM) observation can present the intuitive morphology of asphaltene molecules, and shows that the structure of asphaltenes is in local order as well as long range disorder. The analysis results showed that n-heptane asphaltenes of THAR and Tuo-826 had larger dipole moment values, larger fused aromatic ring systems, larger mean number of stacking layers, and less interlayer spacing between stacking layers than the corresponding n-pentane asphaltenes. The sub-fractions that were inclined to precipitate from the mixture of n-heptane and tetrahydrofuran had larger polarity and less solubility. From the first sub-fraction to the fourth sub-fraction, polarity, mean stacking numbers, and average layer size from the TEM images follow a gradual decrease. The structural parameters derived from TEM images could reflect the largest fused aromatic ring system in asphaltene molecule, yet the parameters derived from 1H NMR data reflected the mean message of poly-aromatic ring systems. The structural parameters derived from TEM images were more consistent with the polarity variation of sub-fractions than those derived from 1H NMR data, which indicates that the largest fused aromatic ring system will play a more important role in the stacking characteristics of

  18. La dimensión social del autoconcepto en el adulto y su relación con el rendimiento académico

    Directory of Open Access Journals (Sweden)

    Francisco MATEOS CLAROS

    2009-11-01

    Full Text Available RESUMEN: Este estudio, realizado con una muestra de 826 adultos, analiza la estructura del autoconcepto, para descubrir qué factor predomina en su configuración, y qué relación guarda con el rendimiento académico. Los resultados muestran que es la dimensión social la variable más relevante de las que conforman el autoconcepto. También se establece el perfil del adulto sociable. Finalmente, se comprueba que la relación entre el autoconcepto y el rendimiento académico, en el adulto, no guarda la estrecha vinculación que se ha encontrado en el caso de los niños.ABSTRACT: Extensive information about academics achievement can be found in the literature of the self concept. This research have been addressed involving the self concept and its factors and configurations. 826 adult students from different universities of Andalucía were evaluate whit the Tennese Self Concept Scale (TSCS, and the most important findings in our job refer to the relation between self concept and academics achievement in adult people. We conclude in a descriptions of the social style.RÉSUMÉ: Cet étude, réalisé avec un échantillonnage de 826 adultes, analyse la structure du AUTOCONCEPT, pour découvrir quel facteur prédomine dans son configuration, et quel relation garde avec le rendement académique. Les résultats montrent qui est la dimension social la variable plus eminent des qui conforment l'autoconcept. Aussi on établi le contour du adulte sociable. Finalement, il se constate que la relation entre l'autoconcept et le rendement académique, dans l'adulte, ne garde pas l'étroit lien qu'on a trouvé dans le cas des enfants.

  19. Preimplantation genetic diagnosis for α-thalassaemia in China

    OpenAIRE

    Xu, Yan-Wen; Zeng, Yan-Hong; Deng, Jie; Liu, Ying; Gao, Ling; Zhou, Can-Quan; Zhuang, Guang-Lun

    2009-01-01

    Purpose To report the usage of PGD for α-thalassaemia with the - -SEA genotype. Method A PGD protocol using fluorescent gap PCR was performed for 51 cycles on 43 couples with the - -SEA genotype. Allele drop-out and amplification failure rates were retrospectively analyzed. Results A total of 472 embryos were biopsied. Amplification was achieved in 390 blastomeres, accounting for an amplification rate of 82.6%. In total, 120 wild-type, 94 heterozygotes and 140 homozygous mutant embryos were d...

  20. Isolation and characterization of microsatellite loci in the whale shark (Rhincodon typus).

    Science.gov (United States)

    Ramírez-Macías, Dení; Shaw, Kristine; Ward, Rocky; Galván-Magaña, Felipe; Vázquez-Juárez, Ricardo

    2009-05-01

    In preparation for a study on population structure of the whale shark (Rhincodon typus), nine species-specific polymorphic microsatellite DNA markers were developed. An initial screening of 50 individuals from Holbox Island, Mexico found all nine loci to be polymorphic, with two to 17 alleles observed per locus. Observed and expected heterozygosity per locus ranged from 0.200 to 0.826 and from 0.213 to 0.857, respectively. Neither statistically significant deviations from Hardy-Weinberg expectations nor statistically significant linkage disequilibrium between loci were observed. These microsatellite loci appear suitable for examining population structure, kinship assessment and other applications.

  1. LA NUEVA VISIÓN DE DESARROLLO RURAL TERRITORIAL Y SU FORMULACIÓN EN EL PLAN DE DESARROLLO

    Directory of Open Access Journals (Sweden)

    Arturo E. Vega V

    2004-07-01

    Full Text Available Al despuntar el siglo XXI, en Colombia aún persistencondiciones de desigualdad y atraso en el medio rural,que se reflejan en el comportamiento de algunosindicadores sociales, entre los que se destacan: delos 12.2 millones de pobladores rurales, el 82.6%se encuentra por debajo de la línea de pobreza y deéstos el 43.4% vive en condiciones de pobrezaextrema; que contrastan con las áreas urbanas, dondeestos niveles se sitúan en el 51% y el 15.8%respectivamente.

  2. AcEST: DK951586 [AcEST

    Lifescience Database Archive (English)

    Full Text Available sapie... 32 2.2 sp|Q9QX27|ST18_RAT Suppression of tumorigenicity protein 18 OS=R... 30 8.5 sp|Q80TY4|ST18_MOUSE Suppression... of tumorigenicity protein 18 OS... 30 8.5 sp|O60284|ST18_HUMAN Suppression of tumorigenicity...+ G +S+ +L +A+ Sbjct: 826 LADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAK 872 >sp|Q9QX27|ST18_RAT Suppression...+ ++ Sbjct: 706 LITCPTPGCDGSGHVTGNYASHRSVSGCPLAD-KTLKSLMAANSQELKCPTPGCDGSGHV 764 >sp|Q80TY4|ST18_MOUSE Suppression...+ ++ Sbjct: 719 LITCPTPGCDGSGHVTGNYASHRSVSGCPLAD-KTLKSLMAANSQELKCPTPGCDGSGHV 777 >sp|O60284|ST18_HUMAN Suppression

  3. Crystal structure of 6-chloro-5-(2-chloroethyl-3-(propan-2-ylideneindolin-2-one

    Directory of Open Access Journals (Sweden)

    K. R. Roopashree

    2015-08-01

    Full Text Available The title compound, C13H13Cl2NO, has a 3-(propan-2-ylideneindolin-2-one core with a Cl atom and a chloroethyl substituent attached to the aromatic ring. Two atoms of the aromatic ring and the chloroethyl substituent atoms are disordered over two sets of sites with a refined occupancy ratio of 0.826 (3:0.174 (3. In the crystal, molecules are linked by pairs of N—H...O hydrogen bonds, forming inversion dimers with an R22(8 ring motif.

  4. Patterns of fractures in accidental and non-accidental injury in children: a comparative study.

    OpenAIRE

    Worlock, P.; Stower, M.; Barbor, P

    1986-01-01

    The incidence and pattern of fractures in children who had been abused were compared with those of fractures sustained by children of similar ages in whom abuse had been excluded. From 1976 to 1982 there were 35 children with fractures resulting from child abuse, and all were aged under 5. Of the 826 children in the control group, seen from January to June 1981, 85% were aged over 5. Abused children were much more likely to have multiple fractures (p less than 0.001) and bruising of the head ...

  5. AcEST: DK957521 [AcEST

    Lifescience Database Archive (English)

    Full Text Available -value 1.7 Report BLASTX 2.2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas...7 sp|P80960|HCY2A_RAPTH Hemocyanin type 2 unit a OS=Rapana thomasi... 32 2.2 >sp|Q9DBQ9|CA026_MOUSE Uncharac... N++ Sbjct: 826 NSNYQ 830 >sp|P80960|HCY2A_RAPTH Hemocyanin type 2 unit a OS=Rapana thomasiana PE=1 SV=2 Len...TX 2.2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zh

  6. Trennungsangst und Agoraphobie bei Achtjährigen

    OpenAIRE

    Federer, Matthias; Herrle, Johannes; Margraf, Jürgen; Schneider, Silvia

    2000-01-01

    Im Zusammenhang mit der Panikstörung wird in der Literatur die Trennungsangsthypo- these diskutiert, welche die Störung mit Trennungsangst als Vorläufer der Panikstörung auffaßt. Die Dresdner Kinder-Angst-Studie (DKAS) untersuchte in einer repräsentativen Stichprobe, ob schon bei Achtjährigen agoraphobische und trennungsängstliche Sym- ptome gehäuft gemeinsam auftreten. Es wurden 826 Kinder gescreent. Mit 230 der Kin- der fand eine diagnostische Einzeluntersuchung statt. Bei ei...

  7. Pubertal development in Danish children

    DEFF Research Database (Denmark)

    Juul, A; Teilmann, G; Scheike, Thomas Harder;

    2006-01-01

    Two recent epidemiological studies (PROS and NHANES III) from the USA noted earlier sexual maturation in girls, leading to increased attention internationally to the age at onset of puberty. We studied the timing of puberty in a large cohort of healthy Danish children in order to evaluate...... differences between USA and Denmark, as well as to look for possible secular trends in pubertal development. Healthy Caucasian children from public schools in Denmark participated in the study which was carried out in 1991-1993. A total number of 826 boys and 1,100 girls (aged 6.0-19.9 years) were included...

  8. A comparative study on the flow over an airfoil using transitional turbulence models

    Science.gov (United States)

    Lin, Mou; Sarlak, Hamid

    2016-06-01

    This work addresses the simulation of the flow over NREL S826 airfoil under a relatively low Reynolds number (Re = 1 × 105) using the CFD solvers OpenFoam and ANSYS Fluent. The flow is simulated using two different transition models, γ-Reθ and k - kL - ω model, and the results are examined against the k - ω SST model without transitional formulations. By comparing the simulations with the available experimental data, we find that the using the transitional model can effectively improve the flow prediction, especially the drag coefficient results, before the stall.

  9. Species composition and number of breeding birds in urban parks in Novi Sad

    OpenAIRE

    Tucakov Marko J.

    2010-01-01

    Numbers of breeding pairs of breeding birds and breeding density are established by territory mapping in Limanski (12.9 ha), Futoški (8.26 ha), and Dunavski (3.9 ha) Parks in Novi Sad from early March to late June 2007. In Limanski Park 11 species of breeders were found, the most numerous being tree sparrow (Passer montanus). Futoški Park had 15 breeders and the most numerous were great tit (Parus major). The smallest number of species (9) bred in Dunavski Park, with great tit as the most com...

  10. EFEITO DA SUPLEMENTAÇÃO DE CAFEÍNA EM PARÂMETROS HEMATOLÓGICOS, IMUNOLÓGICOS E NO DESEMPENHO FÍSICO

    OpenAIRE

    João Rafael Valentim-Silva; Bárbara Aparecida Fernandes Praseres; Luiz Henrique Mourinha; Daniela Cristina Lemos; Bruna Kampfer Bassoli

    2014-01-01

    Therefore was objected to identify the effects of acute supplementation of caffeine with 8 and 16 mg.kg-1 in hematological and immunological parameters and the performance of the Wistar rats submitted in intense exercise until exhaustion. Materials and Methods: was selected 24 Wistar male rats, adults and sedentary with average weight of 174.86 + 8.26g and were randomly divided in control group (water) CON (n=8), CAF8 (n=8) (8mg/kg) e CAF16 (n=8) (16mg/kg) administered the caffeine by gavage ...

  11. Plasmid pGA1 from Corynebacterium glutamicum codes for a gene product that positively influences plasmid copy number.

    OpenAIRE

    Nesvera, J; Pátek, M; Hochmannová, J; Abrhámová, Z; Becvárová, V; Jelínkova, M; Vohradský, J

    1997-01-01

    The complete nucleotide sequence (4,826 bp) of the cryptic plasmid pGA1 from Corynebacterium glutamicum was determined. DNA sequence analysis revealed four putative coding regions (open reading frame A [ORFA], ORFA2, ORFB, and ORFC). ORFC was identified as a rep gene coding for an initiator of plasmid replication (Rep) according to the high level of homology of its deduced amino acid sequence with the Rep proteins of plasmids pSR1 (from C. glutamicum) and pNG2 (from Corynebacterium diphtheria...

  12. Značilnosti gnezdišč mestne lastovke Delichon urbica v Kozjanskem parku: Characteristics of nest-sites chosen by House Martin Delichon urbica at Kozjansko Park:

    OpenAIRE

    Denac, Katarina

    2000-01-01

    During the course of the youth research camp at Kozjanski Park (June 25th July2nd 1999) a research about the breeding ecology of House Martin Delichon urbica in urban and rural habitats was carried out. 826 nests located on 69 buildings in 10 towns were counted. 31% of the nests were occupied by House Martins, 68% were empty. For the remaining 1 % of the nests no information on occupancy could be obtained. The number of occupied nests was probably underestimated since some House Martins had a...

  13. A comparative study on the flow over an airfoil using transitional turbulence models

    DEFF Research Database (Denmark)

    Lin, Mou; Sarlak Chivaee, Hamid

    2016-01-01

    This work addresses the simulation of the flow over NREL S826 airfoil under a relatively low Reynolds number (Re = 1 × 105 ) using the CFD solvers OpenFoam and ANSYS Fluent. The flow is simulated using two different transition models, γ − Reθ and k − kL − ω model, and the results are examined...... against the k − ω SST model without transitional formulations. By comparing the simulations with the available experimental data, we find that the using the transitional model can effectively improve the flow prediction, especially the drag coefficient results, before the stall....

  14. Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe.

    OpenAIRE

    Vizcaino, A. P.; Parkin, D M; Skinner, M. E.

    1995-01-01

    This report presents information on risk factors for oesophageal cancer in Bulawayo, Zimbabwe. The data analysed were from the Cancer Registry of Bulawayo for the years 1963-77, when all registered patients were interviewed using a standard questionnaire. The age-standardised incidence rates in the urban population of Bulawayo in the first 10 year period were 58.6 per 100,000 in men and 8.1 in women. The distribution of risk factors was assessed in 881 oesophageal cancer cases (826 male, 55 f...

  15. Determinants of measles seroprevalence among pregnant women in Paris, France.

    Science.gov (United States)

    Bodilis, H; Goffinet, F; Krivine, A; Andrieu, T; Anselem, O; Tsatsaris, V; Rozenberg, F; Launay, O

    2014-08-01

    Non-immune pregnant women are at risk of severe measles. As the measles vaccination is contraindicated during pregnancy, women should be vaccinated before conception or during the postpartum period. Nevertheless, measles serology is not recommended during pregnancy in France, and there are no data available concerning measles susceptibility and its associated risk factors among pregnant women. The socio-demographic determinants of measles seronegativity have been identified in a prospective cohort of 826 pregnant women in Paris, France. Measles seronegativity was 10.41% (95% CI 8.32-12.50). Women from higher socio-economic groups, born in France after 1980, were more frequently seronegative.

  16. Isolation and characterization of microsatellite loci in the whale shark (Rhincodon typus)

    Science.gov (United States)

    Ramirez-Macias, D.; Shaw, K.; Ward, R.; Galvan-Magana, F.; Vazquez-Juarez, R.

    2009-01-01

    In preparation for a study on population structure of the whale shark (Rhincodon typus), nine species-specific polymorphic microsatellite DNA markers were developed. An initial screening of 50 individuals from Holbox Island, Mexico found all nine loci to be polymorphic, with two to 17 alleles observed per locus. Observed and expected heterozygosity per locus ranged from 0.200 to 0.826 and from 0.213 to 0.857, respectively. Neither statistically significant deviations from Hardy–Weinberg expectations nor statistically significant linkage disequilibrium between loci were observed. These microsatellite loci appear suitable for examining population structure, kinship assessment and other applications.

  17. Fermi-LAT Gamma-ray Observations of Nova Lupus 2016 (ASASSN-16kt)

    Science.gov (United States)

    Cheung, C. C.; Jean, P.; Shore, S. N.; Fermi Large Area Telescope Collaboration

    2016-10-01

    The Fermi Gamma-ray Space Telescope performed a ~6-day Target of Opportunity (ToO) observation of Nova Lupus 2016 (ATel #9538, #9539, CBET #4322) that commenced on September 28. Considering earlier all-sky survey Large Area Telescope (LAT) observations as well, preliminary analysis indicates gamma-ray emission at ~2 sigma was detected around 1 to 2 days after the optical peak on September 25th (pre-validated AAVSO visual lightcurve; ATel #9550, CBET #4322) when the optical spectra show opaque ejecta, similar to previous gamma-ray detected novae (Fermi-LAT collaboration, 2014 Science 345, 554; Cheung et al. 2016 ApJ 826, 142).

  18. Assessment of tannin variation in Tamarisk foliage across a latitudinal gradient

    Science.gov (United States)

    Hussey, A.M.; Kimball, B.A.; Friedman, J.M.

    2011-01-01

    Certain phenotypic traits of plants vary with latitude of origin. To understand if tannin concentration varies among populations of tamarisk (Tamarix spp.) according to a latitudinal gradient, an analytical method was adapted from an enological tannin assay. The tannin content (wet basis) of tamarisk foliage collected from 160 plants grown in a common garden ranged from 8.26 to 62.36 mg/g and was not correlated with the latitude of the original North American plant collection site. Tannins do not contribute to observed differences in herbivory observed among these tamarisk populations.

  19. Ethyl (2E-2-cyano-3-(1-methyl-1H-pyrrol-2-ylprop-2-enoate

    Directory of Open Access Journals (Sweden)

    Abdullah M. Asiri

    2011-09-01

    Full Text Available The 15 non-H atoms of the title compound, C11H12N2O2, are approximately coplanar, the r.m.s. deviation being 0.145 Å. The major deviation from coplanarity is seen in a twist between the ethene (E configuration and pyrrole rings [C—C—N—C torsion angle = −8.26 (18°]. The carbonyl O and cyano N atoms are syn to each other. In the crystal, supramolecular linear tapes linked by C—H...O and C—H...N interactions are further connected by C—H...π(pyrrole interactions.

  20. Do rapid BMI growth in childhood and early-onset obesity offer cardiometabolic protection to obese adults in mid-life?

    DEFF Research Database (Denmark)

    Howe, Laura D; Zimmermann, Esther; Weiss, Ram;

    2014-01-01

    BMI growth (7-13 years) using a multilevel model. Early-onset obesity was defined as obesity at examination for national service. OUTCOME MEASUREMENT: We defined metabolic health at the mid-life clinic as non-fasting serum cholesterol ... groups according to their obesity (BMI ≥30 kg/m(2)) and metabolic health in mid-life. RESULTS: 297 of 1097 (27.1%) of obese men were metabolically healthy; 826 of 1295 (63.8%) non-obese men had at least one metabolic abnormality. There was no evidence...

  1. New, extended biotyping scheme for Campylobacter jejuni, Campylobacter coli, and "Campylobacter laridis".

    OpenAIRE

    Lior, H

    1984-01-01

    A biotyping scheme using improved media and methods for the detection of hippurate hydrolysis, rapid H2S production, and DNA hydrolysis was applied to 1,826 cultures of Campylobacter jejuni, Campylobacter coli and "Campylobacter laridis" isolates from human and nonhuman sources. Four biotypes were identified among C. jejuni: 57.3% of the isolates belonged to biotype I; 36.0%, to biotype II; 4.0%, to biotype III; and 2.7%, to biotype IV. C. coli organisms were differentiated into biotype I (67...

  2. Diagnostic performance of whole-body MRI for the detection of persistent or relapsing disease in multiple myeloma after stem cell transplantation

    International Nuclear Information System (INIS)

    To compare the diagnostic performance of whole-body MRI (WBMRI) with haematological parameters for detecting persistent or relapsing disease in patients with multiple myeloma after stem cell transplantation. Sixty-six WBMRI acquisitions were performed in 33 patients with multiple myeloma at two time points after stem cell transplantation. Extent of disease and inter-test dynamics of intra- and extramedullary myeloma manifestations were compared (kappa statistics) with Uniform Response Criteria, comprising haematological parameters. Using data from 66 sequential WBMRI acquisitions in 33 patients, 10 patients (30.3 %) were classified as having progressive disease and 23 (69.7 %) as being in remission. Eight (80 %) of the ten patients with progressive disease revealed intramedullary lesions, and two patients (20 %) had intra- and extramedullary lesions. WBMRI and laboratory tests were concordant in 26/33 (78.8 %) patients. We found an agreement of 51.2 %, 95 % confidence interval 19.8 %-82.6 %, between results from WBMRI and haematological parameters. WBMRI had a sensitivity of 63.6 %, specificity of 86.4 %, PPV of 70.0 %, NPV of 82.6 % and accuracy of 78.8 % for detection of remission. WBMRI allows the detection and exact localisation of intra- and extramedullary myeloma manifestations after stem cell transplantation, but shows only moderate agreement with routinely performed laboratory tests for determination of remission. (orig.)

  3. Tectonic uplift and sedimentary evolution of the Jiuxi Basin in the northern margin of the Tibetan Plateau since 13 Ma BP

    Institute of Scientific and Technical Information of China (English)

    宋春晖; 方小敏; 李吉均; 高军平; 赵志军; 范马洁

    2001-01-01

    Sediments shed from the northern margin of the Tibetan Plateau, the Qilian Mountains, are widely deposited in the foreland basin, the Jiuxi Basin, archiving plenty of information about the mountain surface uplift and erosion history. The Laojunmiao section, 1960 m thick, representing the upper sequence of the Cenozoic basin sediments, is paleomagnetically dated to about 13-0 Ma BP. Detailed sedimentary study of this sequence has revealed five sedimentary fades associations which determine four stages of sedimentary environment evolution. They are: (I) the half-deep lake system before 12.18 Ma BP, (Ⅱ) the shallow lake system between 12.18 and 8.26 Ma BP, (Ⅲ) the fan delta dominated sedimentary system in dry climate between 8.26 and 6.57 Ma BP, and (IV) alluvial fan system since 6.57 Ma BP. The associated mountain erosion and uplift are suggested to have experienced three phases, that is, tectonic stable (13-8.26 Ma BP), gradual uplift (8.26-<4.96 Ma BP), and rapid intermittent uplift (>3.66-0 Ma BP). Th

  4. 实施基本药物制度对基层医疗卫生机构的影响及政策建议%The impact of institutions and policy recommendations for the implementation of national basic medicine system for primary health care system

    Institute of Scientific and Technical Information of China (English)

    孟宏伟; 尹文强; 黄冬梅; 于倩倩; 郭洪伟; 李伟

    2012-01-01

    With the deepening of health system reform, as an important parts of national health system reform in China, national essential drug policy has been rapidly implemented in primary health care institutions. As of 2011 March, national essential drug policy has covered 82.6% of the primary health care institutes. By literature review, the impact of national essential drug policy in primary health care institutes has been summarized and suggestions h for improving the basic drug system has been presented.%随着医改的深入推进,在基层医疗卫生机构实施基本药物制度作为医改的一项重要内容,在全国范围内全面展开.截至2011年3月底,已覆盖全国82.6%的基层医疗机构.通过查阅相关文献,汇总分析实施基本药物制度对基层医疗机构产生的影响,提出针对性政策建议,为完善基本药物制度提供借鉴.

  5. Diagnostic performance of whole-body MRI for the detection of persistent or relapsing disease in multiple myeloma after stem cell transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Bannas, Peter; Hentschel, Hannah B.; Bley, Thorsten A.; Derlin, Thorsten; Yamamura, Jin; Adam, Gerhard; Weber, Christoph [University Medical Center Hamburg-Eppendorf, Department of Diagnostic and Interventional Radiology, Hamburg (Germany); Treszl, Andras; Eulenburg, Christine [University Medical Center Hamburg-Eppendorf, Department of Medical Biometry and Epidemiology, Hamburg (Germany); Stuebig, Thomas; Kroeger, Nicolaus [University Medical Center Hamburg-Eppendorf, Department of Stem Cell Transplantation, Hamburg (Germany)

    2012-09-15

    To compare the diagnostic performance of whole-body MRI (WBMRI) with haematological parameters for detecting persistent or relapsing disease in patients with multiple myeloma after stem cell transplantation. Sixty-six WBMRI acquisitions were performed in 33 patients with multiple myeloma at two time points after stem cell transplantation. Extent of disease and inter-test dynamics of intra- and extramedullary myeloma manifestations were compared (kappa statistics) with Uniform Response Criteria, comprising haematological parameters. Using data from 66 sequential WBMRI acquisitions in 33 patients, 10 patients (30.3 %) were classified as having progressive disease and 23 (69.7 %) as being in remission. Eight (80 %) of the ten patients with progressive disease revealed intramedullary lesions, and two patients (20 %) had intra- and extramedullary lesions. WBMRI and laboratory tests were concordant in 26/33 (78.8 %) patients. We found an agreement of 51.2 %, 95 % confidence interval 19.8 %-82.6 %, between results from WBMRI and haematological parameters. WBMRI had a sensitivity of 63.6 %, specificity of 86.4 %, PPV of 70.0 %, NPV of 82.6 % and accuracy of 78.8 % for detection of remission. WBMRI allows the detection and exact localisation of intra- and extramedullary myeloma manifestations after stem cell transplantation, but shows only moderate agreement with routinely performed laboratory tests for determination of remission. (orig.)

  6. Exploration of Extraction Method of Beef Tissue's DNA for Real-time PCR Detection%用于Real-time PCR检测的牛肉组织DNA提取方法探索

    Institute of Scientific and Technical Information of China (English)

    李璟; 陈世界; 陈洋

    2012-01-01

    使用Chelex-100提取牛肉组织DNA,并用紫外分光光度法检测所提取的DNA浓度和纯度,结果表明所提取的DNA A260nm/A 280nm在1.662~1.826之间,纯度较高.Real-time PCR扩增提取的DNA模板,表现出较高的敏感性.该DNA提取方法效率较高,操作简便,能够获得较高质量的DNA,适合检疫部门的快速检测需要.%Chelex-100 was used to extract DNA from beef tissue. The DNA samples were then tested by UV spectrophotome-try. The results revealed that A260nm of DNA was 1.662-1.826. Real-time PCR results showed good sensitivity. The processes of DNA extraction method was simple, rapid and able to obtain DNA with high quality, which could be used for rapid detection of animal tissue by inspect and quarantine department.

  7. [Bioremediation of chromium (VI) contaminated site by reduction and microbial stabilization of chromium].

    Science.gov (United States)

    Zheng, Jia-Chuan; Zhang, Jian-Rong; Liu, Xi-Wen; Xu, Qian; Shi, Wei-Lin

    2014-10-01

    Chromium (VI) contaminated soil samples were collected from a chemical plant in Suzhou. Firstly, the reduced soil was prepared by adding reagent (Stone-sulfure reagent) into polluted soil to transfer most chromium (VI) into chromium (III), then a nutrient solution was introduced into the reduced soil, and the stabilized soil was obtained after 60 days culturing. The chromium (VI) content of the three kinds of soil was analyzed. The results showed that the chromium (VI) content in toxicity characteristic leaching liquid (TCLL) dropped by 96. 8% (from 8.26 mg · L(-1) to 0.26 mg · L(-1)), and the total chromium content dropped by 95.7% (from 14.66 mg · L(-1) to 0.63 mg · L(-1)) after bioremediation in 5% nutrient solution. Additionally, the durability of chromium stabilization was tested by potassium permanganate oxidation and sterilization of microbe-treated soil. After oxidation, the chromium (VI) content in TCLL of the reduced soil was increased from 8.26 mg · L(-1) to 14.68 mg · L(-1). However, the content after bioremediation was decreased to 2.68 mg · L(-1). The results of sterilization demonstrated that the death of microbe had no significant effect on the stabilization of chromium. Consequently, the research in this paper demonstrated the feasibility of bioremediation of chromium (VI) polluted soil through reduction followed by stabilization/soilidification, and provided a technique with low cost but high efficiency.

  8. Mitochondrial gene mutations and type 2 diabetes in Chinese families

    Institute of Scientific and Technical Information of China (English)

    LI Ming-zhen; YU De-min; YU Pei; LIU De-min; WANG Kun; TANG Xin-zhi

    2008-01-01

    Background Numerous mitochondrial DNA mutations are significantly correlated with development of diabetes. This study investigated mitochondrial gene, point mutations in patients with type 2 diabetes and their families. Methods Unrelated patients with type 2 diabetes(n=826)were randomly recruited; unrelated and nondiabetic subjects (n=637)served as controls. The clinical and biochemical data of the participants were collected. Total genome was extracted from peripheral leucocytes. Polymerase chain reaction, restriction fragment length polymorphism (PCR-RFLP)and clonig techniques were used to screen mitochondrial genes including np3316,np3394 and np3426 in the ND1 region and np3243 in the tRNALeu (UUR). Results In 39 diabetics with one or more mitochondrial gene point mutations, the prevalence(4.7%,39/826)of mtDNA mutations was higher than that(0.7%,5/637)in the controls. The identical mutation was found in 23 of 43 tested members from three pedigrees. Affected family members presented with variable clinical features ranging from normal glucose tolerance to impaired glucose tolerance (IGT)(n=2),impaired fasting glucose(IFG)(n=1)to type 2 diabetes (n=13)with 3 family members suffering from hearing loss. Conclusions Type 2 diabetes in China is associated with several mitochondrial gene mutations. Aged patients with diabetic family history had a higher prevalence of mutation and various clinical pictures. Mitochondrial gene mutation might be one of the genetic factors contributing to diabetic familial clustering.

  9. Immunization coverage among children in Al-Taizyah district, Taiz Governorate, Yemen

    Directory of Open Access Journals (Sweden)

    Nabil Ahmed Al-Rabeei

    2014-12-01

    Full Text Available Introduction: At least 2 million people die every year from diseases preventable by vaccines recommended by the World Health Organization. Objective: To assess the routine immunization coverage among children aged 12-23 month and to determine the reasons for unvaccinated. Methods: We conducted a community-based survey in Al-Taizyah district, Taiz governorate, Yemen. Information about vaccination status and related barriers was collected for 420 children from 1st March to 31st March 2012. Results: 49.8% of the children had vaccination cards. About 69.5% of the children were fully vaccinated by cards and by history, 15.5% were partially vaccinated and 15% not vaccinated. As a regards to crude vaccination coverage, 82.9% of children were received BCG vaccine. OPV1 vaccine was 82.6%. Pentavalent1 was 82.6%. Measles 1 represented for 71.7% and vitamin A1 was 46.4%. 91% was valid doses for OPV1 and 93% for pentavalent1. Only 76% of measles1 dose was valid. The high scores14% of drop-out rate was recorded between BCG and Measles. The main reasons for partially vaccinated and unvaccinated of children were the lack of information 61.7%. Conclusion: There is low vaccination coverage among children aged 12-23 months. There is a need to raise the awareness of community about vaccination and EPI services in Al-Taizyah district.

  10. Gallstones Risk Factor and Prevalence in the Elderly in Jeju Island

    Energy Technology Data Exchange (ETDEWEB)

    Sim, Hyun Sun; Choi, Joon Lock; Park, Jae Jin; Lee, Su Yeon; Lee, Ji Min; Jung, Hong Ryang; Lim, Chung Hwan; Kim, Jung Gu [Dept. of Radiological Science, Hanseo University, Cheju (Korea, Republic of)

    2009-09-15

    Gallbladder stone is the most common disease of biliary tract. It is lead to acute abdominal pain. The cholecystitis which is caused by in gallbladder stone occurs frequently and the possibility of the gallbladder cancer comes to be high. Our study was designed to determine the prevalence and risk factors gallbladder stone in a population who community. We enrolled a total of 826 (male : 297, female : 529) persons who 60 or older in Jeju-do 10 places from 2008 July one months. The height, weight, liver function tests, lipid profile, fasting blood sugar, were all measurement. They had their gallbladder examined with using ultrasonography. Statistical significance was defined as a p-value less than 0.05. Among 826 persons, gallbladder stone was found in 49 persons (5.9%). The male is 6.1% and the female is 5.8%, the male 1.03 times appeared more highly the female. The body mass index above of 23.0 kg/m{sup 2} with the gallbladder stone was 69.3% (p<0.047). The gallbladder stone appeared highly according to age increases. The obesity is the risk factor of gallbladder stone. The weight management and diet control is a possibility of reducing a gallbladder stone creation.

  11. Generation of a 90 000 molecular weight fragment from human plasma angiotensin-I-converting enzyme by enzymatic or alkaline hydrolysis.

    Science.gov (United States)

    Yotsumoto, H; Lanzillo, J J; Fanburg, B L

    1983-12-12

    A catalytically active Mr 90 000 fragment was generated from native Mr 140 000 human plasma angiotensin-I-converting enzyme after treatment with reagents that induced a perturbation of the native tertiary conformation. Treatment of converting enzyme with 6 M urea produced an aggregation of molecules that was susceptible to proteolysis by either trypsin, chymotrypsin or Staphylococcus aureus V8 proteinase to generate the Mr 90 000 converting enzyme. Also, 1 M ammonium hydroxide, pH 11.3, or 0.01 M sodium hydroxide, pH 11.3, cleaved converting enzyme to the Mr 90 000 fragment. Degradation was not an autocatalytic phenomenon, since it was not prevented by inhibition of converting enzyme with EDTA. The enzymatically mediated, but not the alkaline mediated, cleavage was inhibited by specific converting enzyme inhibitors captopril and Merck L-154,826. This suggests that captopril and Merck L-154,826 can prevent converting-enzyme degradation by preserving a conformation that does not have sites exposed to proteolytic enzymes. This conformation may mimic the native conformation which is quite resistant to serine proteinases.

  12. Gallstones Risk Factor and Prevalence in the Elderly in Jeju Island

    International Nuclear Information System (INIS)

    Gallbladder stone is the most common disease of biliary tract. It is lead to acute abdominal pain. The cholecystitis which is caused by in gallbladder stone occurs frequently and the possibility of the gallbladder cancer comes to be high. Our study was designed to determine the prevalence and risk factors gallbladder stone in a population who community. We enrolled a total of 826 (male : 297, female : 529) persons who 60 or older in Jeju-do 10 places from 2008 July one months. The height, weight, liver function tests, lipid profile, fasting blood sugar, were all measurement. They had their gallbladder examined with using ultrasonography. Statistical significance was defined as a p-value less than 0.05. Among 826 persons, gallbladder stone was found in 49 persons (5.9%). The male is 6.1% and the female is 5.8%, the male 1.03 times appeared more highly the female. The body mass index above of 23.0 kg/m2 with the gallbladder stone was 69.3% (p<0.047). The gallbladder stone appeared highly according to age increases. The obesity is the risk factor of gallbladder stone. The weight management and diet control is a possibility of reducing a gallbladder stone creation.

  13. Evaluation of T2-weighted and dynamic contrast-enhanced MRI in localizing prostate cancer before repeat biopsy

    Energy Technology Data Exchange (ETDEWEB)

    Cheikh, Alexandre Ben; Girouin, Nicolas [Hopital Edouard Herriot, Hospices Civils de Lyon, Department of Urinary and Vascular Radiology, Lyon (France)]|[Universite de Lyon, Lyon (France)]|[Universite de Lyon 1, faculte de medecine Lyon Nord, Lyon (France); Colombel, Marc; Marechal, Jean-Marie [Hopital Edouard Herriot, Hospices Civils de Lyon, Department of Urology, Lyon (France); Gelet, Albert [Hopital Edouard Herriot, Hospices Civils de Lyon, Department of Urology, Lyon (France)]|[Inserm, U556, Lyon (France); Bissery, Alvine; Rabilloud, Muriel [Hospices Civils de Lyon, Department of Biostatistics, Lyon (France)]|[Universite de Lyon 1, UMR CNRS 5558, Laboratoire Biostatistiques-Sante, Pierre-Benite (France); Lyonnet, Denis [Hopital Edouard Herriot, Hospices Civils de Lyon, Department of Urinary and Vascular Radiology, Lyon (France)]|[Universite de Lyon, Lyon (France)]|[Universite de Lyon 1, faculte de medecine Lyon Nord, Lyon (France)]|[Inserm, U556, Lyon (France); Rouviere, Olivier [Hopital Edouard Herriot, Hospices Civils de Lyon, Department of Urinary and Vascular Radiology, Lyon (France)]|[Universite de Lyon, Lyon (France)]|[Universite de Lyon 1, faculte de medecine Lyon Nord, Lyon (France)]|[Inserm, U556, Lyon (France)]|[Hopital Edouard Herriot, Department of Urinary and Vascular Radiology, Pavillon P Radio, Lyon Cedex 03 (France)

    2009-03-15

    We assessed the accuracy of T2-weighted (T2w) and dynamic contrast-enhanced (DCE) 1.5-T magnetic resonance imaging (MRI) in localizing prostate cancer before transrectal ultrasound-guided repeat biopsy. Ninety-three patients with abnormal PSA level and negative prostate biopsy underwent T2w and DCE prostate MRI using pelvic coil before repeat biopsy. T2w and DCE images were interpreted using visual criteria only. MR results were correlated with repeat biopsy findings in ten prostate sectors. Repeat biopsy found prostate cancer in 23 patients (24.7%) and 44 sectors (6.6%). At per patient analysis, the sensitivity, specificity, positive and negative predictive values were 47.8%, 44.3%, 20.4% and 79.5% for T2w imaging and 82.6%, 20%, 24.4% and 93.3% for DCE imaging. When all suspicious areas (on T2w or DCE imaging) were taken into account, a sensitivity of 82.6% and a negative predictive value of 100% could be achieved. At per sector analysis, DCE imaging was significantly less specific (83.5% vs. 89.7%, p < 0.002) than T2w imaging; it was more sensitive (52.4% vs. 32.1%), but the difference was hardly significant (p = 0.09). T2w and DCE MRI using pelvic coil and visual diagnostic criteria can guide prostate repeat biopsy, with a good sensitivity and NPV. (orig.)

  14. Correlation Between MRI and Ultrasonographic Findings in Meniscal Injuries of the Knee.

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Sasani

    2009-01-01

    Full Text Available "nIntroduction: The purpose of this study was to evaluate ability of ultrasonography in the diagnosis of injuries of the knee menisci including tear, intrasubstance degeneration (ISD and cyst. "nMaterials and Methods: This study included ultrasound examination of knee joints of 100 patients after MR imaging, who were referred by clinicians without informing us about their symptoms and physical examinations. Then ultrasonographic results were correlated with MRI findings. "nResults: The 23 meniscal tear diagnosis made in MR examination in different segments of menisci and 19 (82.6% cases were diagnosed sonographically and the rest were reported as ISD (13% and normal (4.4%. Among the 69 cases in which MR examination interpreted as ISD in different segments, 66.7% were reported as ISD and others were diagnosed as meniscal tear (10% and normal(23% by sonography. There was a significant correlation between ultrasound and MR findings in meniscal tears (82.6% and relatively significant in ISD(66.7%. "nConclusion: Ultrasonographic study of the menisci is an inexpensive, noninvasive, easily available and reliable imaging modality.   

  15. Developmental time of immature forms of Sabethes aurescens Lutz (Diptera, Culicidae from artificially perforated bamboo in the rain forest of southern Brazil Tempo de desenvolvimento de formas imaturas de Sabethes aurescens Lutz (Diptera, Culicidae provenientes de bambus artificialmente perfurados em floresta atlântica do sul do Brasil

    Directory of Open Access Journals (Sweden)

    Gerson Azulim Muller

    2009-12-01

    Full Text Available The development time of the immature forms of Sabethes aurescens Lutz, 1905, from perforated bamboo in the southern Brazil rain forest was studied under laboratory conditions. Mean development periods were 5±2.23, 10±5.20, 14±8.26, 36±13.90 and 9±2.43 days, respectively, for the four larval instars and pupae. The 4th instar of females was longer than that of males. Implications of the long development time of the immature forms of Sa. aurescens are discussed.O tempo de desenvolvimento de formas imaturas de Sabethes aurescens Lutz, 1905 de bambus perfurados da floresta atlântica do sul do Brasil foi estudado em condições de laboratório. O período médio de desenvolvimento foi de 5±2,23; 10±5,20; 14±8,26; 36±13,90 e 9±2,43 dias respectivamente, para os quatro instares larvais e pupa. O 4º instar das fêmeas foi mais longo do que o dos machos. Implicações do longo tempo de desenvolvimento das formas imaturas de Sa. aurescens são discutidas.

  16. Sonographic evaluation of thyroglossal duct cysts in children

    Energy Technology Data Exchange (ETDEWEB)

    Ahuja, A.T.; King, A.D.; Metreweli, C

    2000-10-01

    BACKGROUND AND AIMS: Thyroglossal duct cysts (TDC) in children have a variable sonographic appearance. Some reports have suggested that TDCs appear on ultrasound as well defined, cystic masses with thin walls and posterior enhancement, whereas others have documented a heterogeneous echopattern within these lesions. In our experience, although TDCs in children have a variable ultrasound appearance, the most common appearance is that of a pseudosolid mass closely related to the hyoid bone. In this study we report on 23 patients with thyroglossal duct cysts and document the ultrasonic patterns. PATIENTS AND METHODS: All patients in whom the diagnosis of TDC was made clinically (by at least two head and neck surgeons) and in whom ultrasound detected a cystic mass related to the hyoid bone, were included in this study. Sonograms of 23 children with TDCs were reviewed. The features evaluated included their location, internal echogenicity, posterior enhancement, the presence of septa, a solid component and a fistulous tract. The echopattern was not correlated with the biopsy results. RESULTS: Three patterns of TDCs were identified: anechoic (13%); pseudosolid (56.5%); and a heterogeneous pattern (30.5%). The majority were midline (82.6%), showed posterior enhancement (56.5%), and had thin walls (82.6%). CONCLUSION: On ultrasound, TDCs in children are not simple cysts but have a complex pattern ranging from a typical anechoic cyst to a pseudosolid appearance (most common). Ahuja, A.T. (2000)

  17. Short-term environmental variability in cold-water coral habitat at Viosca Knoll, Gulf of Mexico

    Science.gov (United States)

    Davies, Andrew J.; Duineveld, Gerard C. A.; van Weering, Tjeerd C. E.; Mienis, Furu; Quattrini, Andrea M.; Seim, Harvey E.; Bane, John M.; Ross, Steve W.

    2010-02-01

    The Lophelia pertusa community at Viosca Knoll (VK826) is the most extensive found to date in the Gulf of Mexico. As part of a multi-disciplinary study, the physical setting of this area was described using benthic landers, CTD transects and remotely operated vehicle observations. The site was broadly characterised into three main habitats: (1) dense coral cover that resembles biogenic reef complexes, (2) areas of sediment, and (3) authigenic carbonate blocks with sparse coral and chemosynthetic communities. The coral communities were dominated by L. pertusa but also contained numerous solitary coral species. Over areas that contained L. pertusa, the environmental conditions recorded were similar to those associated with communities in the north-eastern Atlantic, with temperature (8.5-10.6 °C) and salinity (˜35) falling within the known species niche for L. pertusa. However, dissolved oxygen concentrations (2.7-2.8 ml l -1) and density ( σ Θ, 27.1-27.2 kg m -3) were lower and mass fluxes from sediment trap data appeared much higher (4002-4192 mg m -2 d -1). Yet, this species still appears to thrive in this region, suggesting that L. pertusa may not be as limited by lower dissolved oxygen concentrations as previously thought. The VK826 site experienced sustained eastward water flow of 10-30 cm s -1 over the 5-day measurement period but was also subjected to significant short-term variability in current velocity and direction. In addition, two processes were observed that caused variability in salinity and temperature; the first was consistent with internal waves that caused temperature variations of 0.8 °C over 5-11 h periods. The second was high-frequency variability (20-30 min periods) in temperature recorded only at the ALBEX site. A further pattern observed over the coral habitat was the presence of a 24 h diel vertical migration of zooplankton that may form part of a food chain that eventually reaches the corals. The majority of detailed studies concerning

  18. 2′,4′-二氟-2-(1H-1,2,4-三唑-1-基)苯乙酮的合成%Synthesis of 2′, 4′-difluoro-2-(1H-1, 2,4-triazol-1-yl) Acetophenone

    Institute of Scientific and Technical Information of China (English)

    常瑜; 翟红; 王秀兰

    2006-01-01

    在相转移催化剂存在的条件下,以1,2,4-三氮唑和2-氯-2′,4′-二氟苯乙酮为原料合成2′,4′-二氟-2-(1H-1,2,4-三唑-1-基)苯乙酮,分别讨论了原料配比、反应时间、缚酸剂、溶剂对合成反应的影响,确定了最佳合成工艺条件,产物收率可达82.6%.

  19. Impact of using essential drug list: analysis of drug use indicators in Gaza Strip.

    Science.gov (United States)

    Fattouh, R; Abu Hamad, B

    2010-08-01

    A descriptive cross-sectional study evaluated the compliance of physicians with the Palestinian essential drug list (EDL) in all the government primary care clinics in the Gaza Strip. While 67.4% reported currently using the EDL 51.2% of these physicians reported problems in using it. The mean number of drugs per prescription was 1.92, the percentage of drugs prescribed from the EDL was 97.9% but the percentage of drugs prescribed by generic name was only 5.5%. A copy of the EDL was available in 28.3% of clinics and the availability of key drugs was 82.6%. The compliance of physicians with the EDL was generally good, but more efforts are needed to encourage prescribing by generic name and to ensure the supply of key drugs. PMID:21469571

  20. Effect of radiation of fracture toughness and microstructure of a high-Cu RPV weld

    International Nuclear Information System (INIS)

    A radiation-sensitive reactor pressure vessel (RPV) weld with intentionally enhanced copper, nickel, and manganese content, designated KS-01, is characterized in terms of static initiation (KIC, KJC) and Charpy impact toughness in the unirradiated and irradiated conditions. After neutron irradiation to a fluence of 0.8x1019 neutron/cm-2 (E>1 MeV) at a temperature of 288degC, this weld exhibited a large Charpy T4IJ shift of 169 K, a large shift of the fracture toughness transition temperature of 165 K, a decrease in upper shelf energy (USE) from 118 J to ∼78 J, and an increase in the yield strength from 600 to 826 MPa. Atom probe tomography revealed a high number density (∼3x1024 m-3) of Cu-, Mn-, Ni-, Si- and P-enriched precipitates and a lower number density (∼1x1023 m-3) of P clusters. (author)

  1. NOD2/CARD15 genotype and common gastrointestinal diseases in 43 600 individuals

    DEFF Research Database (Denmark)

    Yazdanyar, S.; Nordestgaard, B.G.

    2010-01-01

    Objectives. NOD2/CARD15 is involved in the innate immune response and three polymorphisms in this gene (Arg702Trp rs2066844, Gly908Arg rs2066845 and Leu1007fsinsC rs5743293) have been associated with risk of the rare Crohn's disease. We tested the hypothesis that polymorphisms in NOD2/CARD15...... associate with risk of nine common gastrointestinal diseases. Design and setting. We genotyped 43 596 white individuals from the Danish general population followed for 31 years, during which time 782 developed oesophagitis and reflux, 1395 ulcus ventriculi and duodeni, 1384 gastritis and dyspepsia, 1407...... appendicitis, 646 irritable bowel syndrome, 1301 infectious diseases of the gastrointestinal tract, 681 anal fissure, fistula and abscess, 826 gastrointestinal cancer and 161 developed cancer in liver and pancreas. Results. Some 89% were non-carriers, 11% heterozygotes, 0.15% homozygotes and 0.23% compound...

  2. 5-Chloro-2-methyl-3-phenylsulfonyl-1-benzofuran

    Directory of Open Access Journals (Sweden)

    Hong Dae Choi

    2008-07-01

    Full Text Available The title compound, C15H11ClO3S, was prepared by the oxidation of 5-chloro-2-methyl-3-phenylsulfanyl-1-benzofuran with 3-chloroperoxybenzoic acid. There are two symmetry-independent molecules in the asymmetric unit. The dihedral angles formed by the phenyl ring and the plane of the benzofuran system are 77.80 (8 and 78.34 (8°. The crystal structure is stabilized by aromatic π–π stacking interactions between the furan ring and the benzene rings of neighbouring benzofuran fragments from two symmetry-independent molecules; the centroid–centroid distances within the stacks are 3.689 (4, 3.702 (4, 3.825 (4 and 3.826 (4 Å. Additionally, the stacked molecules exhibit inter- and intramolecular C—H...O interactions.

  3. Study on the preparation and retarded releasing characteristics of cardanol modifier coated urea%腰果酚醛树脂包膜尿素的制备及缓释性能

    Institute of Scientific and Technical Information of China (English)

    卢玉栋; 林筱璇; 叶琳; 柯金炼; 吴宗华; 尤宇文

    2010-01-01

    用腰果酚醛树脂作为包膜材料制备了一系列不同膜厚的包膜尿素.并采用水浸泡溶解法、淋溶法、土壤法评价所得包膜尿素的缓释特性.结果表明,利用腰果酚醛树脂包膜后的尿素具有明显的缓释性能,包覆量为26.3%的单层包膜尿素30 min后溶解率为50%,而包覆量为82.6%的双层包膜尿素113 h后溶出率为83.16%,双层包膜尿素的缓释性能明显好于单层包膜尿素.

  4. Estimating spontaneous mutation rates at enzyme loci in Drosophila melanogaster

    International Nuclear Information System (INIS)

    Spontaneous mutations were accumulated for 1,620,826 allele-generations on chromosomes that originated from six stem second chromosomes of Drosophila melanogaster. Only null-electromorph mutations were detected. Band-electromorph mutations were not found. The average rate of null-electromorph mutations was 2.71 x 10-5 per locus per generation. The 95% confidence interval (μn) was 1.97 x 10-5 n -5 per locus per generation. The upper 95% confidence limit of the band-electromorph mutation rate (μB) was 2.28 x 10-6 per locus per generation. It appeared that null mutations were induced by movable genetic elements and that the mutation rates were different from chromosome to chromosome. (author)

  5. Application of Bayesian Network Learning Methods to Land Resource Evaluation

    Institute of Scientific and Technical Information of China (English)

    HUANG Jiejun; HE Xiaorong; WAN Youchuan

    2006-01-01

    Bayesian network has a powerful ability for reasoning and semantic representation, which combined with qualitative analysis and quantitative analysis, with prior knowledge and observed data, and provides an effective way to deal with prediction, classification and clustering. Firstly, this paper presented an overview of Bayesian network and its characteristics, and discussed how to learn a Bayesian network structure from given data, and then constructed a Bayesian network model for land resource evaluation with expert knowledge and the dataset. The experimental results based on the test dataset are that evaluation accuracy is 87.5%, and Kappa index is 0.826. All these prove the method is feasible and efficient, and indicate that Bayesian network is a promising approach for land resource evaluation.

  6. Resolved CCD Photometry of Pluto and Charon

    International Nuclear Information System (INIS)

    Highly resolved CCD images of Pluto and Charon near maximum separation are measured with point spread function fitting techniques to determine independent magnitudes and an accurate separation for Pluto and Charon. A measured separation of 0.923 + or - 0.005 arcsec at a position angle of 173.3 + or - 0.3 deg on June 18, 1987 UT produced a value of 19558.0 + or - 153.0 km for the radius of Charon's orbit. An apparent B magnitude of 14.877 + or - 0.009 and (B-I) color of 1.770 + or - 0.015 are determined for Pluto, while Charon is fainter with B = 18.826 + or - 0.011 and slightly bluer with (B-I) = 1.632 + or - 0.018. 18 references

  7. Guía del investigador americanista : Mérida, Venezuela

    OpenAIRE

    S. O. Samudio A., Edda; Cardoza S., Ebert

    2013-01-01

    La Ciudad de Mérida, fundada en 1558 por el capitán Juan Rodríguez Suárez, se extiende en una hermosa y extensa terraza del valle del río Chama, donde de acuerdo al Censo de 2011, habitan 221.879 habitantes que representan el 28% de la población total del Estado de Mérida que posee 826.720 habitantes, en tanto, a su área Metropolitana se atribuyen 345.489 individuos. Mérida, centro educativo desde el temprano periodo hispánico, es la sede de la ilustre y bicentenaria Universidad de Los Andes,...

  8. A relativistic equivalence principle for the electrostatic fields of charged particles

    International Nuclear Information System (INIS)

    It is shown that the intensity of the phenomenon of precession of the perihelion of the planet Mercury (43''/century) maintains the same relation with the precession of the perihelion of the electron (rosetta-like pattern) in the interior of the hydrogen atom, with a relative potential phisub(e/g) = 5.624 X 1048 between the electrostatic over the gravitational field, to compare with the relative potential phisub(e/g) = 6.81 X 1048 found by direct calculation. With such data, the relative potency between the earth gravitational field/gravitational field prevailing in the orbit of Mercury was found to be 1.211 times that of the earth gravitational field (taken as 1.00), or taking the reciprocal, the ratio between Mercury/Earth gravitational fields was found to be 0.826, a value not exceeding 4% of the expected value found by direct calculation (0.793). (Auth.)

  9. The Cost of Collaborating with Climbers of Status Hierarchies

    DEFF Research Database (Denmark)

    Jeppesen, Jacob; Vaarst Andersen, Kristina

    , but at times individuals or organizations successfully climb the status hierarchy or fall from grace. A growing body of research focuses on these status dynamics rather than static status measures. Based on data from 826 scientists affiliated with a Large Scale Research Facility (LSRF) collaborating on 1282 on......-site and 151,302 off-site publications we analyze relationships between status dynamics, tie formation and performance among scientists. We find that there is a cost of collaborating with rising stars – in the form of increasing status - as collaboration partners’ positive status shifts is negatively...... associated with the focal scientist’s performance. Also, we find that the association between individual scientists’ status attainment and tie creation follows and inverted U-shape, while the relationship between status attainment and performance is positive. Finally, we find that status decline has...

  10. Separation of Red(Y_2O_3:Eu~(3+)),Blue(BaMgAl_(10)O_(17):Eu~(2+))and Green(CeMgAl_(10)O_(17):Tb)Rare Earth Phosphors by Liquid/Liquid Extraction

    Institute of Scientific and Technical Information of China (English)

    MEI Guangjun; RAO Peng; Mitsuaki Matsuda; Toyohisa Fujita

    2009-01-01

    A novel process for separation of red(Y_2O_3:Eu~(3+)),blue(BaMgAl_(10)O_(17):Eu~(2+))and green(CeMgAl_(10)O_(17):Tb~3)rare earth fluorescent powders was proposed.At first,the blue powder can be extracted selectively from an aqueous solution using a chelating collector 2-thenoyltrifluoroacetone (TTA)dissolved in heptane at alkaline pH condition,then,chloroform was used for extracting the green powder into organic phase.The red phosphor remains in aqueous phase with potassium sodium tartrate depressant(PST).Therefore,three phosphors can be separated successfully from their artificial mixtures by liquid/liquid extraction,and grades and recovery of separated products reach respectively as follows:red is 96.9%and 95.2%,blue is 82.7%and 98.8%,green is 94.6%and 82.6%.

  11. Neurospora experiment P-1037. Quarterly progress report to the National Aeronautics and Space Administration, October 1--December 15, 1966

    Energy Technology Data Exchange (ETDEWEB)

    1967-12-01

    The main values of the 302 gantry exercise were to check the preparation of the Neurospora experiment and the spacecraft loading procedure under timed conditions and to provide final assurance that necessary operations can be completed with appropriate inspection in the allotted time. Because of the brief time interval between the 302 Gantry Exercise and the scheduled Biosatellite A flight, no attempt was made to assay for forward-mutation frequecies; however, biocompatibility tests were performed on the 302 hardware by plating conidia from a number of the modules in the usual fashion to assay survival. The average heteokaryotic conidial survival was 82.6%, which is sufficiently high for use of the conidia in a forward-mutation experiment. Calibration of thermoluminescent dosimeters was carried out using a /sup 85/Sr ..gamma.. source.

  12. Quantification of available K from commercial sources using Rb-85 as a tracer

    International Nuclear Information System (INIS)

    A field experiment was conducted in a soil classified a Typic Dystrandept located at Sta. Catalina experiment station, INIAP. The objective of this study was evaluate potassium availability of three comercial sources of K fertilizers: KCl, K2SO4 and sulpomag and their effects on potato yield. Soil was labeled with KCl which had 8.26 per cent of Rb-85 and the evaluation was made using the isotopic dilution method. Assumptions made in the experiment and calculation procedures are presented. The amount of available K to the plant is expressed in KCl units. Results of the experiment indicate that 1 kg of KCl is equivalent to 1.7 kg of K2SO4 and 3.7 kg of sulpomag

  13. TPX: Contractor preliminary design review. Volume 5, Manufacturing R ampersand D

    International Nuclear Information System (INIS)

    TPX Insulation ampersand Impregnation R ampersand D test results are reported for 1x2 samples designed for screening candidate conduit insulation systems for TPX PF and TF coils. The epoxy/glass insulation system and three proposed alternate insulation systems employing Kapton, was evaluated in as received sample condition and after 10 thermal cycles in liquid nitrogen. Two DGBA impregnation systems, Shell 826 and CTD101K were investigated. Square incoloy 908 and 316 LN stainless hollow conduits were used for 1x2 sample fabrication. Capacitance, dielectric loss, and insulation resistance dielectric characteristics were measured for all samples. Partial discharge performance was measured for samples either in air, under silicon oil, or under liquid nitrogen up to 10kVrms at 60 Hz. Hipot screening was performed at 10 kVdc. The samples were cross sectioned and evaluated for impregnation quality. The implications of the test results on the TPX preliminary design decision are discussed

  14. Dicty_cDB: FC-BS12 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available FC (Link to library) FC-BS12 (Link to dictyBase) - - - Contig-U16022-1 FC-BS12P (Li...nk to Original site) FC-BS12F 555 FC-BS12Z 271 FC-BS12P 826 - - Show FC-BS12 Library FC (Link to library) Clone ID FC-BS...al site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/FC/FC-BS/FC-BS12Q.Seq.d/ Representative seq. ID FC-BS...12P (Link to Original site) Representative DNA sequence >FC-BS12 (FC-BS12Q) /CSM/FC/FC-BS/FC-BS...cing significant alignments: (bits) Value FC-BS12 (FC-BS12Q) /CSM/FC/FC-BS/FC-BS12Q.Seq.d/ 1100 0.0 VSD839 (

  15. The correlation of fecundability among twins: Evidence of a genetic effect on fertility?

    DEFF Research Database (Denmark)

    Christensen, Kaare; Kohler, Hans-Peter; Basso, Olga;

    2003-01-01

    born 1953-1982. Fecundability was assessed as the waiting time to pregnancy at the first attempt to achieve a pregnancy. RESULTS: The reported time to pregnancy for males was slightly shorter than for females but there were no sex differences in intrapair similarity. We found an intrapair correlation......BACKGROUND: Numerous rare genetic conditions are known to influence fecundability in both males and females. It is less clear to what extent more subtle genetic differences influence fecundability on a population level. METHODS: In 1994 a population-based survey was conducted among Danish twins...... in time to pregnancy for 645 monozygotic twin pairs (r = 0.22; 95% confidence interval = 0.12 to 0.32), but no intrapair correlation for 826 like-sex dizygotic twin pairs (r = 0.00; 95% confidence interval = -0.09 to 0.10). CONCLUSIONS: The correlation in time to pregnancy for monozygotic twins suggests...

  16. Clinical and CT Histological Diagnosis of Orbital Tumors

    Institute of Scientific and Technical Information of China (English)

    HU Yanhua; WANG Jie; XIAO Shiyi

    2000-01-01

    The clinical manifestation and characteristics of CT image of 117 cases of orbital tumors in our hospital were investigated. The hemangioma had the highest incidence, and the less common tumors were, in sequence of incidence, pseudotumor, dermoid cysts, neurilemmoma, polymorphous adenoma and meningioma. The sensitivity in diagnosis of orbital tumor by CT was 93.3%. The coincidence of CT histological diagnosis with pathology were 83.3 %, 82.6 % and 71.4% for dermoid.cysts, hemangioma, and pseudotumor respectively, but the general coincidence of CT histological diagnosis with pathology was only 67.8 %. When CT was combined with ultrasound, cytological examination and clinical manifestations, the accuracy of histological diagnosis could be improved to 83.3 %.

  17. Asteroid Lightcurve Analysis at the Oakley Southern Sky Observatory: 2009 October thru 2010 April

    Science.gov (United States)

    Albers, Kenda; Kragh, Katherine; Monnier, Adam; Pligge, Zachary; Stolze, Kellen; West, Josh; Yim, Arnold; Ditteon, Richard

    2010-10-01

    Photometric data for 44 asteroids were collected over 54 nights of observing during 2009 October thru 2010 April at the Oakley Southern Sky Observatory. The asteroids were: 826 Henrika, 918 Itha, 983 Gunila, 1049 Gotho, 1167 Dubiago, 1181 Lilith, 1227 Geranium, 1604 Tombaugh, 1636 Porter, 1826 Miller, 1977 Shura, 2004 Lexell, 2196 Ellicott, 2303 Retsina, 2307 Garuda, 2601 Bologna, 2609 Kiril-Metodi, 2851 Harbin, 2881 Meiden, 3118 Claytonsmith, 3324 Avsyuk, 3640 Gostin, 4207 Chernova, 4536 Drewpinsky, 4838 Billmclaughlin, 5235 Jean-Loup, 5274 Degewij, 5240 Kwasan, (6019) 1991 RO6, 6091 Mitsuru, 6961 Ashitaka, (7111) 1985 QA1, (8228) 1996 YB2, 11017 Billputnam, (13023) 1988 XT1, (14741) 2000 EQ49, 15938 Bohnenblust, 16463 Nayoro, (17633) 1996 JU, (21023) 1989 DK, 21558 Alisonliu, (21594) 1998 VP31, (34459) 2000 SC91, and (189099) 2001 RO.

  18. 新辅助化疗宫颈癌46例疗效分析

    Institute of Scientific and Technical Information of China (English)

    陈远征

    2006-01-01

    目的:探讨新辅助化疗(NACT)宫颈癌的临床疗效.方法:用DDP为基础的NACT后再手术或放疗,分析NACT的疗效.结果:NACT组的完全缓解率为41.3%,总有效率90.2%,5 a生存率82.6%,较对照组均有显著提高,各种手术并发症发生率较对照组明显下降.结论:NACT是治疗宫颈癌的有效途径,尤其是IB2期巨块型宫颈癌患者,在缩小肿癌体积提高生存率上有显著疗效.

  19. Intestinal parasites in Iaualapiti indians from Xingu Park, Mato Grosso, Brazil

    Directory of Open Access Journals (Sweden)

    Cláudio Santos Ferreira

    1991-12-01

    Full Text Available Brine flotation and gravity sedimentation coproscopical examinations were performed in stool samples from 69 of the 147 Iaualapiti Indians of the Xingu Park, Mato Grosso State, Brazil. Intestinal [arasites were present in 89.9% of the population examined. High rates of prevalence were found for some parasite species. Ancylostomidae, 82.6%; Enterobius vermicularis, 26.1%; Ascaris lumbricoides, 20.3%; and Entamoeba coli, 68.1%. Infection by Trichuris trichuria, Schistosoma mansoni, Taenia spp. and Hymenolepis nana was not detected. Helminth's prevalence in children aged one year or less was comparatively low (33.3%. Quantitative coproscopy was done in positive samples for Ascaris and Ancylostomidae and the results expressed in eggs per gram of feces (EPG. Quantitative results revealed that worm burdens are very low and overdispersed in this Indian tribe, a previously unreported fact.

  20. Preparation and characterization of polyvinyl alcohol-Aloe vera hydrogel using gamma radiation

    International Nuclear Information System (INIS)

    Hydrogels of polyvinyl alcohol with Aloe vera gel have been prepared using gamma radiation (8-26 kGy), and were characterized by FT-IR and their degree of swelling was determined. Those obtained with doses higher than 11 kGy show good mechanical properties. The degree of swelling of these films decreases from 2500 to 1000% as the radiation dose increasing, but from 18 kGy it doesn't change too much. The film obtained at 15 kGy has good water absorbent capacity at basic pH. These films have no antimicrobial activity but they act as an effective barrier against microorganisms. This hydrogels have potential to be used as dressings for the treatment of wounds and burns. (orig.)

  1. 2006有趣读物全总结

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ 《美国最佳》系列图书编辑者戴夫·艾格斯(Dave Eggers)是《迈特》(MIGHT)杂志的创办编辑以及多本杂志的撰搞者,目前是McSweeney期斯此前作品有《怪才的荒诞与忧伤》(AHEARTBREADING WORK OF STAGGERING GENIUS),《你应该知道我们的速度》(YOU SHALL KNOW OUR VELOCITY!),他成产了826 Valencia--一个专为年轻人开设的旧金山写作实验室.

  2. Six Key Topics for Automated Assessment Utilisation and Acceptance

    Directory of Open Access Journals (Sweden)

    Torsten REINERS

    2011-04-01

    Full Text Available Automated assessment technologies have been used in education for decades (e.g., computerised multiple choice tests. In contrast, Automated Essay Grading (AEG technologies: have existed for decades; are `good in theory' (e.g., as accurate as humans, temporally and financially efficient, and can enhance formative feedback, and yet; are ostensibly used comparatively infrequently in Australian universities. To empirically examine these experiential observations we conducted a national survey to explore the use of automated assessment in Australian universities and examine why adoption of AEG is limited. Quantitative and qualitative data were collected in an online survey from a sample of 265 staff and students from 5 Australian universities. The type of assessment used by the greatest proportion of respondents was essays/reports (82.6%, however very few respondents had used AEG (3.8%. Recommendations are made regarding methods to promote technology utilisation, including the use of innovative dissemination channels such as 3D Virtual Worlds.

  3. Differences in outcome for positive margins in a large cohort of breast cancer patients treated with breast-conserving therapy.

    Science.gov (United States)

    Jobsen, Jan J; Van Der Palen, Job; Ong, Francisca; Meerwaldt, Jacobus H

    2007-01-01

    A study of the possible difference in outcome for positive margins for invasive carcinoma (IC) versus ductal carcinoma in situ (DCIS), and with regard to different age categories in a large prospective cohort of patients with invasive breast cancer. A total of 2 291 BCT were analyzed. Margins were positive for IC in 8.7% and for DCIS in 4.6%. The median follow-up was 83 months. The 10-year local recurrence-free survival for negative margins vs. positive margins for IC vs. positive for DCIS for women 40 years 94.7% vs. 92.6% vs. 82.6% (HR4.2). The 10-year distant disease-free survival for negative margins vs. positive margins for IC vs. positive for DCIS women 40 years.

  4. Diferencias en las estadísticas e juego entre los equipos ganadores y perdedores de la Copa del Rey 2008 de balonmano masculino [Difference in the statistics of game between the winning and losing teams of the king’s cup 2008 of male handball

    Directory of Open Access Journals (Sweden)

    Francisco Javier Sáez Blázquez

    2010-03-01

    Full Text Available ResumenEl objetivo de este estudio es analizar en que se diferencian los equipos ganadores y perdedores de la Copa del Rey 08 de balonmano masculino en función de las estadísticas de juego. Los datos de los partidos (n=7 fueron facilitados por la ASOBAL. Las variables empleadas en el estudio podemos dividirlas en primarias (goles marcados, goles de 9, 6, 7 m y contraataque, lanzamientos fallados de 9, 6, 7 m. y contraataque, lanzamientos totales, pases de gol, perdidas,  recuperaciones,  paradas de 9, 6, 7m., contraataque y paradas totales, exclusiones, descalificaciones directas y expulsiones y en secundarias (Posesiones, CEO, CRO, CED, CRD. Todos los datos de las estadísticas de juego fueron normalizadas a 100 posesiones.El análisis se realizó mediante el SPSS 17.0 para Windows, se empleo una prueba t para medidas independientes a través de la cual observamos que los equipos ganadores se diferencian de los perdedores en las siguientes variables: goles marcados (t100 =2.907; p≤ 0.05, lanzamientos fallados 6m (t100 = - 3.335; p≤ 0.01, goles contraataque (t100 =2.196; p≤ 0.05, paradas 6m (t100 = 2.406; p≤ 0.05, CEO (t100 = 2.907; p≤ 0.05 CRO (t100 = 3.826; p≤ 0.01, CED (t100 = -2.907; p≤ 0.05, CRD (t100 = 3.826; p≤ 0.01. Podemos concluir afirmando que tanto la fase defensiva como los contraataques son aspectos muy relevantes a la hora de alcanzar el éxito, este hecho debe ser tenido en cuenta por los entrenadores y preparadores físicos a la hora de elaborar su proceso de entrenamiento. Palabras clave: Balonmano, Copa del Rey, Victoria, Derrota, Diferencias, Coeficientes del rendimiento.   Abstract The purpose of this study is to analyze the difference between the winning and losing teams of the King's Cup 08 of male handball depending on the statistics of game. The data was provided by the ASOBAL (n = 7. The variables used in the study were divided in two kind of variables: primary (goals scored, goals of 9, 6, 7 m

  5. Giant resonance spectroscopy of sup 4 sup 0 Ca with the (e,e'x) reaction (I): Experiments and overview of results

    CERN Document Server

    Diesener, H; Neumann-Cosel, P V; Richter, A; Schrieder, G; Stascheck, A; Stiller, A; Carter, J

    2001-01-01

    The sup 4 sup 0 Ca(e,e'x; x=p,alpha) reaction has been measured in the giant resonance excitation region for E sub x approx =8-26 MeV. The present article is the first out of three describing the experiments and giving an overview of the results. Data were taken at four momentum transfers in the range q=0.26-0.66 fm sup - sup 1. Angular correlations for decay to the ground state and low-lying states of sup 3 sup 9 K and sup 3 sup 6 Ar could be extracted as a function of excitation energy in sup 4 sup 0 Ca. Excitation energy spectra integrated over the particle emission angle were generated for the various resolved decay channels. Comparisons of the giant resonance cross-section distributions with results using other electromagnetic or hadronic probes have been made and good agreement is found in most cases.

  6. Evaluation of the physico-chemical properties of a new polysaccharide gum from Prosopis africana.

    Science.gov (United States)

    Adikwu, M U; Ezeabasili, S I; Esimone, C O

    2001-01-01

    The gum obtained from the ripe seeds of Prosopis africana was processed to compendial standard for plant gums and characterised. Toxicological studies of the polysaccharide on mice showed the material to be safe. The material hydrates slowly in aqueous media to form a colloidal dispersion. Swelling studies on the gum shows that the gum has a higher swelling capacity than methylcellulose. Rheological studies showed that the material is more viscous than tragacanth gum at equivalent concentrations. Acid hydrolysis and thin layer chromatography of the resulting hydrolysates showed that the gum contains glucose, fructose, galactose and xylose as the monosaccharide components. Microbial tests showed the gum to contain 8.26 x 10(4) viable cells per gram when freshly prepared. Other properties of the gum evaluated includes; melting or charring temperature, optical properties, true density, ash values, element content as well as its reactions with lead subacetate solution and 0.02 M iodine.

  7. Preparing Attitude Scale to Define Students‟ Attitudes about Environment, Recycling, Plastic andPlastic Waste

    Directory of Open Access Journals (Sweden)

    Cagri AVAN

    2011-01-01

    Full Text Available The aim of this study is to introduce an attitude scale in order to define students‟ attitudes about environment, recycling, plastics, plastic waste. In this study, 80 attitude sentences according to 5-point Likert-type scale were prepared and applied to 492 students of 6th grade in the Kastamonu city center of Turkey. The scale consists of cognitive, affective, and psychomotor skills domains. After the factor analysis it was found that they have 3, 4 and 5 factors accordingly. After the reliability analysis the alpha values for cognitive, affective and psychomotor scales are .854, .871 and .826 respectively. As a result, it is found that the scale can be used to define cognitive, affective and psychomotor attitudes.

  8. FUTURES with Jaime Escalante

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    The United States Department of Energy awarded the Foundation for Advancements in Science and Education (FASE) $826,000 as support to produce the second set of FUTURES segments consisting of 12, 15-minute programs. The programs provide motivation for students to study math by connecting math to the work place and real-life problem scenarios. The programs are broadcast in 50 states through PBS Elementary and Secondary Service (E/SS). The grant term ended on December 16, 1993 and this final report documents program and financial activity results. The 12 episodes are titled: Animal Care, Meteorology, Mass Communication, Advanced Energy, Oceanography, Graphic Design, Future Habitats, Environmental Science & Technology, Fitness & Physical Performance, Interpersonal Communications, Advanced Transportation and Product Design. Each program addresses as many as ten careers or job types within the broader field named. Minority and gender-balanced role models appear throughout the programs.

  9. 1-Methyl-3-octylimidazolium Polyoxomolybdate Ionic Liquid with Low Melting Point and High Stability:Preparation and Photocatalytic Activity

    Institute of Scientific and Technical Information of China (English)

    DONG Tao; XU Yan-qing; CHEN Fa-wang; CHI Ying-nan; HU Chang-wen

    2011-01-01

    The polyoxometalate(POM)-imidazole ionic liquid(IL) [C8mim]2[Mo6O19](C8mim=l-methyl-3-octylimidazolium) with a low melting point of 82.6 ℃ was successfully prepared and characterized by FTIR, XPS, NMR, TG and so on. The polyoxomolybdate-based IL has high stability, and its decomposing temperature reaches 321 ℃,which is higher than that of l-alkyl-3-methylimidazolium halides IL. Further photocatalytic performances of the IL were measured via degrading dye rhodamine B(RB) in aqueous solution under the UV light irradiation. The experi ments show that the conversion of RB reaches 80.5% after 90 min under UV-light and the degradation efficiency de pends on the pH value of the solution, irradiation time and the dosage of the IL and so on.

  10. Demultiplexer for wavelength division multiplexing over polymer optical fibers applicable for high-volume production

    Science.gov (United States)

    Fischer, Ulrich H. P.; Höll, Sebastian; Haupt, Matthias; Joncic, Mladen

    2015-10-01

    Polymer optical fibers (POF) offer only transmission so far with one wavelength at 650 nm. In order to increase the overall transfer rate, the key element for wavelength division multiplexing (WDM) over POF will be presented. This element is a demultiplexer (DEMUX), which was designed in polymethylmethacrylate with an optical grating on an aspherical mirror to be produced by injection molding in a further development steps. The master was produced by diamond turning as a master for injection molding replication. The results of the different simulations followed by the development steps and the measurements of the prototype are presented. This prototype is used as a DEMUX in a WDM system with four wavelengths. In the WDM system, bit-error ratio (BER) measurements with an 8.26 Gb/s cumulated data rate in an offline processed discrete multitone modulation technique have been achieved over 100 m SI-POF at a BER of 10-3.

  11. Electric Power monthly, November 1995 with data for August 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-15

    This report presents monthly electricity statistics, with the purpose of providing energy decisionmakers with accurate, timely information that may be used in forming various perspectives on electric issues that lie ahead. EIA collected the information in this report to fulfill its data collection and dissemination responsibilities; the information are from six data sources: forms EIA-759, FERC Form 423, EIA-826, EIA-861, EIA-860, and Form OE-417R. An article on reclicensing and environmental issues affecting hydropower is included. Then the statistics are presented in: US electric power at a glance, utility net generation, utility consumption of fossil fuels, fossil-fuel stocks at utilities, fossil fuel receipts and costs, utility sales/revenue/average revenue per kWh, and monthly plant aggregates. Finally, nonutility power producer statistics, bibliography, technical notes, and a glossary are presented.

  12. Preparation of pellets containing highly soluble drug by extrusion/spheronisation and coating with Kollicoat® SR 30D

    Directory of Open Access Journals (Sweden)

    Itamar Francisco Andreazza

    2011-04-01

    Full Text Available The aim of this study was to prepare and evaluate the pellets, containing a highly soluble drug (ascorbic acid, by the extrusion-spheronization process and coated with a release controlling polymer. The coating (undertaken in a fluid bed was applied to three batches of the pellets with a dispersion of Kollicoat® SR 30 D, with each batch of pellets receiving a different level of polymer (5.07; 8.26 and 10.35%. The coated pellets were evaluated for sphericity by imaging analysis and comparative dissolution profile with a product commercially available in Brazil. All of the evaluated samples presented adequate physical properties and the dissolution profile of those coated with 5.07% of polymer proved to be similar to that of the commercially available brand name.

  13. Academic Support Services in U.S. and Canadian Medical Schools

    Directory of Open Access Journals (Sweden)

    Norma S. Saks, EdD

    2004-04-01

    Full Text Available Background: Academic support services play a critical but largely undocumented role in helping medical students meet the challenges of the curriculum. Purpose: To determine the prevalence of academic support programs in medical schools, and to find out how these are conceptualized and implemented. Methods: Questionnaires were sent to medical schools in the US and Canada. Questions addressed specific services, providers, and funding. Results: The survey was returned by 86 of the 135 (67.7% schools. Almost all (95.3% provide academic support in the first two years, and a large majority in third (82.6% and fourth (79% year. Great variability exists in the infrastructure and funding of the programs, and in the training of the providers. Conclusions: Academic support is common, but has broad interpretation; services are varied. Programs are conceptualized differently, some to provide specific assistance to pass courses, and others for skill development, to enhance self-directed, life-long learning.

  14. Synthesis and TFT Properties of Fluorenyl Cored Conjugated Compound for Organic Thin Film Transistors.

    Science.gov (United States)

    Kim, You Geun; Shaik, Baji; Jang, Yong Ju; Park, Song Yi; Kim, Jin Young; Lee, Sang-Gyeong

    2016-03-01

    The 5,5'-(4,4'-(9,9-dioctyl-9H-fluorene-2,7-diyl)bis(4,1-phenylene))bis(2-hexylthieno[3,2-b]thiophene) FCBT (6) was synthesized by connecting the fluorenyl, thienothiophenyl and phenyl units. The compound was characterized by FT-IR, H1NMR, C13NMR and mass spectroscopy. The compound has shown good solubility and thermal stability over 417 degrees C. The compound has shown hole mobility of 4.76 x 10(-6) cm2Ns. The on-off ratio and threshold voltage were 7.5 x 10(2) and -8.26 V respectively.

  15. Abnormal albuminuria and blood pressure rise in incipient diabetic nephropathy induced by exercise

    DEFF Research Database (Denmark)

    Christensen, Cramer

    1984-01-01

    diastolic blood pressure was elevated [92.1 mm Hg +/- 6.0 (mean +/- SD)] compared to D2 (80.9 mm Hg +/- 4.8, 2P = 0.003%) and C (79.5 mm Hg +/- 12.4, 2P = 1.2%). Baseline systolic blood pressure was not significantly different in the three groups, but systolic blood pressure was more elevated at 600 kpm....../min in D3 (193.0 mm Hg +/- 23.0) compared to D2 (170.5 +/- 17.3, 2P = 1.2%) and C (157.5 mm Hg +/- 20.9, 2P = 0.07%). Baseline albumin excretion in D3 was 82.6 micrograms/min X/ divided by 2.5 (geometric mean X/ divided by tolerance factor) and during exercise the maximal albumin excretion rose to 195...

  16. Wronskian solutions of the T-, Q- and Y-systems related to infinite dimensional unitarizable modules of the general linear superalgebra gl(M|N)

    International Nuclear Information System (INIS)

    In [1] (Z. Tsuboi, Nucl. Phys. B 826 (2010) 399, (arXiv:0906.2039)), we proposed Wronskian-like solutions of the T-system for [M,N]-hook of the general linear superalgebra gl(M|N). We have generalized these Wronskian-like solutions to the ones for the general T-hook, which is a union of [M1,N1]-hook and [M2,N2]-hook (M=M1+M2, N=N1+N2). These solutions are related to Weyl-type supercharacter formulas of infinite dimensional unitarizable modules of gl(M|N). Our solutions also include a Wronskian-like solution discussed in [2] (N. Gromov, V. Kazakov, S. Leurent, Z. Tsuboi, JHEP 1101 (2011) 155, (arXiv:1010.2720)) in relation to the AdS5/CFT4 spectral problem

  17. STUDIES ON MASTITIS AMONG DAIRY BUFFALOES

    Directory of Open Access Journals (Sweden)

    Rashid Ahmad

    2001-09-01

    Full Text Available A total of 2340 mammary glands of 585 primiparous and pluriparous lactating buffaloes in different stages of lactation were examined with California Mastitis Test ( CMT and laboratory examination was carried out to identify the most prevalent micro-organisms in clinical and sub-clinical mastitis. The physical examination revealed 2.61 per cent blind teats and CMT revealed 6.71 per cent positive quarters for mastitis. Microbiological examination of 157 sub-clinical mastitis milk samples and 46 clinical mastitis milk samples was carried out. There was high occurrence of streptococci (35.46% followed by staphylococci (33.99%, E. coli (27.09%, pseudomonas spp. ( 1.97% and Corynaebacterium pyogenes (1.48%. The in vitro sensitivity revealed kanamyciin (82.6%, highly effective against various isolates followed by gentamycin (53.0%.

  18. Performance of a constructed wetland in treating brackish wastewater from commercial recirculating and super-intensive shrimp growout systems.

    Science.gov (United States)

    Shi, Yonghai; Zhang, Genyu; Liu, Jianzhong; Zhu, Yazhu; Xu, Jiabo

    2011-10-01

    A recirculating aquaculture system was developed for treating Pacific white shrimp (Litopenaeus vannamei) production wastewater using an integrated vertical-flow (IVF) and five connected integrated horizontal flow (IHF) constructed wetlands as water treatment filters for mesohaline conditions (8.25‰-8.26‰ salinity). The constructed wetlands demonstrated the ability to reduce total nitrogen, total ammonia nitrogen, nitrite nitrogen, nitrate nitrogen, total phosphorous, chemical oxygen demand, and total suspended solids to levels significantly lower than those in effluents from culture tanks. Various water quality parameters in the culture tanks were deemed suitable for shrimp culture. The actual ratio of wetland area (A(w)) to culture tank area (A(t)) was 1.1439, and the estimated optimal ratio A(w)/A(t) was approximately 1. The IVF-IHF wetlands showed flexibility and reliability in consistently removing the main pollutants from commercial recirculating and super-intensive shrimp growout systems throughout the culture period. PMID:21852127

  19. Electric power annual 1997. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The Electric Power Annual presents a summary of electric power industry statistics at national, regional, and State levels. The objective of the publication is to provide industry decisionmakers, government policy-makers, analysts, and the general public with data that may be used in understanding US electricity markets. The Electric Power Annual is prepared by the Electric Power Division; Office of Coal, Nuclear, Electric and Alternate Fuels; Energy Information Administration (EIA); US Department of Energy. Volume 1 -- with a focus on US electric utilities -- contains final 1997 data on net generation and fossil fuel consumption, stocks, receipts, and cost; preliminary 1997 data on generating unit capability, and retail sales of electricity, associated revenue, and the average revenue per kilowatthour of electricity sold (based on a monthly sample: Form EIA-826, ``Monthly Electric Utility Sales and Revenue Report with State Distributions``). Additionally, information on net generation from renewable energy sources and on the associated generating capability is included in Volume 1 of the EPA.

  20. Unsteady behavior of a confined jet in a cavity at moderate Reynolds numbers

    Energy Technology Data Exchange (ETDEWEB)

    Bouchet, G [Laboratoire IUSTI, UMR 7343 CNRS, Aix Marseille Universite, 5 rue Enrico Fermi, 13453 Marseille Cedex 13 (France); Climent, E, E-mail: Gilles.Bouchet@univ-amu.fr, E-mail: Gilles.Bouchet@univ-provence.fr, E-mail: climent@imft.fr [Institut de Mecanique des Fluides de Toulouse, UMR 5502 Universite de Toulouse-CNRS-INPT-UPS, 1 allee du Professeur Camille Soula, 31400 Toulouse (France)

    2012-04-01

    Self-sustained oscillations in the sinuous mode are observed when a jet impinges on a rigid surface. Confined jet instability is experimentally and numerically investigated here at moderate Reynolds numbers. When the Reynolds number is varied, the dynamic response of the jet is unusual in comparison with that of similar configurations (hole-tone, jet edge, etc). Modal transitions are clearly detected when the Reynolds number is varied. However, these transitions result in a reduction of the frequency, which means that the wavelength grows with Reynolds number. Moreover, the instability that sets in at low Reynolds number, as a subcritical Hopf bifurcation, disappears only 25% above the threshold. Then, the flow becomes steady again and symmetric. This atypical behavior is compared with our previous study on a submerged fountain (Bouchet et al 2002 Europhys. Lett. 59 826). (paper)

  1. The value of bone scintigraphy in the diagnosis and follow-up of Langerhans' cell histiocytosis

    International Nuclear Information System (INIS)

    Objective: To investigate the clinical value of bone scintigraphy in the diagnosis and follow-up of Langerhans' cell histiocytosis (LCH). Methods: Whole-body bone scintigraphy was performed on 23 LCH patients. Results: Nineteen of 23 patients (82.6%) showed positive in their bone scan. Eight cases were with cranial abnormal uptake, clavicle, rib and pelvis involvements were seen and each was of 3 cases, respectively, upper limb, lower limb and spinal abnormal uptakes were seen in 2, 4 and 5 patients, respectively, and 1 child had photon deficient area in the lower part of the sternum. Among 19 positive scintigrams, solitary bone lesion was shown in 9 patients (47.4%). Conclusion: Characters of bone scintigraphy in LCH are useful in the diagnosis and follow-up of this disease. (authors)

  2. Isolation and characterization of diesel degrading bacteria, Sphingomonas sp. and Acinetobacter junii from petroleum contaminated soil

    Science.gov (United States)

    Zhang, Qiuzhuo; Wang, Duanchao; Li, Mengmeng; Xiang, Wei-Ning; Achal, Varenyam

    2014-03-01

    Two indigenous bacteria of petroleum contaminated soil were characterized to utilize diesel fuel as the sole carbon and energy sources in this work. 16S rRNA gene sequence analysis identified these bacteria as Sphingomonas sp. and Acinetobacter junii. The ability to degrade diesel fuel has been demonstrated for the first time by these isolates. The results of IR analyses showed that Sphingomonas sp. VA1 and A. junii VA2 degraded up to 82.6% and 75.8% of applied diesel over 15 days, respectively. In addition, Sphingomonas sp. VA1 possessed the higher cellular hydrophobicities of 94% for diesel compared to 81% by A. junii VA2. The isolates Sphingomonas sp. VA1 and A. junii VA2 exhibited 24% and 18%, respectively emulsification activity. This study reports two new diesel degrading bacterial species, which can be effectively used for bioremediation of petroleum contaminated sites.

  3. Optimization of Fluorine Plasma Treatment for Interface Improvement on HfO2/In0.53Ga0.47As MOSFETs

    Directory of Open Access Journals (Sweden)

    Yen-Ting Chen

    2012-03-01

    Full Text Available This paper reports significant improvements in the electrical performance of In0.53Ga0.47As metal-oxide-semiconductor field-effect transistors (MOSFET by a post-gate CF4/O2 plasma treatment. The optimum condition of CF4/O2 plasma treatment has been systematically studied and found to be 30 W for 3–5 min. Approximately 5× reduction in interface trap density from 2.8 × 1012 to 4.9 × 1011 cm−2eV−1 has been demonstrated with fluorine (F incorporation. Subthreshold swing has been improved from 127 to 109 mV/dec. Effective channel mobility has been enhanced from 826 to 1,144 cm2/Vs.

  4. Shallow vs. Deep Fluid Sources In Hydrothermal Systems: New Insights From VOC Composition In Fumarolic Discharges And Soil Gases Of Yellowstone National Park (USA)

    Science.gov (United States)

    Tassi, F.; Capecchiacci, F.; Montegrossi, G.; Caliro, S.; Chiodini, G.; Vaselli, O.

    2008-12-01

    The origin of non-methane volatile organic compounds (VOCs) in hydrothermal fluids is related to two distinct mechanisms regulated by different thermodynamic conditions (e.g. Des Marais et al., 1981; Mango, 2000; Capaccioni and Mangani, 2001): i) thermogenic reactions, such as catalytic reforming and/or thermal cracking, which proceed within the main reservoir at medium-to-high temperature (150-350°C) and reduced conditions; ii) biodegradation processes, occurring at relatively shallow depth, where uprising fluids have Agricol. Food Chem., 56, 789- 795. Capaccioni, B., Mangani, F., 2001. Earth Planet. Sci. Lett., 188, 543-555. Des Marais, D.J., Donchin, J.H., Truesdell, A.H., Nehring, N.L., 1981. Nature, 292, 826-828. Mango, F.D., 2000. Geochim. Cosmochim. Acta, 64, 1265-1277.

  5. Chemical composition and efficacy of dichloromethane extract of Croton sphaerogynus Baill. (Euphorbiaceae) against the cattle tick Rhipicephalus microplus (Acari: Ixodidae).

    Science.gov (United States)

    Righi, Adne A; Motta, Lucimar B; Klafke, Guilherme M; Pohl, Paula C; Furlan, Cláudia M; Santos, Deborah Y A C; Salatino, Maria L F; Negri, Giuseppina; Labruna, Marcelo B; Salatino, Antonio

    2013-02-18

    The cattle tick Rhipicephalus microplus is widely distributed in tropical and subtropical regions, causing high economic impact on cattle production. The control of tick infestations is regarded worldwide as critical and has been based on the use of organophosphates, synthetic pyretroids, amitraz and recently ivermectin and fipronil. The present study reports the analysis by gas chromatography/mass spectrometry of the constituents of leaf extracts of Croton sphaerogynus and results of acaricidal activity against the cattle tick R. microplus. The larval package test using the serial dilutions 0.625%, 1.25%, 2.5%, 5.0%, 10.0% and 20.0% (v/v) gave mortality rates 2.25%, 8.26%, 8.81%, 24.80%, 83.66% and 99.32%, respectively. Relevant constituents identified were abietanes, podocarpenes and clerodane type furano diterpenes. The present work may represent a possibility of attainment of natural substances useful for the control of R. microplus.

  6. Prohibitin is associated with antioxidative protection in hypoxia/reoxygenation-induced renal tubular epithelial cell injury

    Science.gov (United States)

    Zhou, Tian-Biao; Qin, Yuan-Han; Lei, Feng-Ying; Huang, Wei-Fang; Drummen, Gregor P. C.

    2013-11-01

    Prohibitin is an evolutionary conserved and pleiotropic protein that has been implicated in various cellular functions, including proliferation, tumour suppression, apoptosis, transcription, and mitochondrial protein folding. We recently demonstrated that prohibitin downregulation results in increased renal interstitial fibrosis. Here we investigated the role of oxidative stress and prohibitin expression in a hypoxia/reoxygenation injury system in renal tubular epithelial cells with lentivirus-based delivery vectors to knockdown or overexpress prohibitin. Our results show that increased prohibitin expression was negatively correlated with reactive oxygen species, malon dialdehyde, transforming-growth-factor-β1, collagen-IV, fibronectin, and apoptosis (r = -0.895, -0.764, -0.798, -0.826, -0.817, -0.735 each P mechanisms that counteract oxidative stress and extracellular matrix accumulation and therefore has an antioxidative effect.

  7. Photodynamic Therapy With YAG-OPO Laser for Early Stage Lung Cancer

    Directory of Open Access Journals (Sweden)

    Harubumi Kato

    1997-01-01

    Full Text Available Photodynamic therapy (PDT utilizing Photofrin is proving to be effective for the treatment of early stage lung cancers. The effect of PDT utilizing YAG-OPO laser as new light source was evaluated in 26 patients (29 lesions with early stage lung cancers. YAG-OPO laser is solid state tunable laser which is easy to change wavelength between 620 and 670 nm exciting various kinds of photosensitizers. Moreover, YAG-OPO laser is more reliable, smaller and has less consumables than argon-dye laser or excimer-dye laser. As the result of PDT with YAG-OPO laser, complete remission (CR was obtained in 82.6% of the 29 lesions, partial remission (PR in 13.8% and no change (NC was obtained in 3.4%. We conclude that PDT utilizing YAG-OPO laser is efficacious in the treatment of early stage lung cancers and can achieve complete remission.

  8. Effect of technological factors on bacterial leaching of low-grade Ni-Cu sulfide ore

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The bioleaching of a low-grade Ni-Cu sulfide ore from Jinchuan Mine with Thiobacillus ferrooxidans (TF5) and Thiobaxillus thiooxxidlans (TT) was investigated. The effect of pH, the initial cell numbers of bacteria, the pulp den sity and the ratio of TF5 and TT on leaching was described, and the favorable bioleaching conditions for the ore were ex perimentally confirmed. The aeration leaching, agitation leaching with air bubbling, and column leaching were respective ly tested. The highest recovery was achieved in the aeration leaching. After leaching for 20 d with pulp density of 15 %, the extractions of Ni, Cu and Co were respectively 95.4 %, 48.6 % and 82.6 %.

  9. Environmentally benign processing of YAG transparent wafers

    Science.gov (United States)

    Yang, Yan; Wu, Yiquan

    2015-12-01

    Transparent yttrium aluminum garnet (YAG) wafers were successfully produced via aqueous tape casting and vacuum sintering techniques using a new environmentally friendly binder, a copolymer of isobutylene and maleic anhydride with the commercial name ISOBAM (noted as ISOBAM). Aqueous YAG slurries were mixed by ball-milling, which was followed by de-gassing and tape casting of wafers. The final YAG green tapes were homogenous and flexible, and could be bent freely without cracking. After the drying and sintering processes, transparent YAG wafers were achieved. The microstructures of both the green tape and vacuum-sintered YAG ceramic were observed by scanning electronic microscopy (SEM). Phase compositions were examined by X-ray diffraction (XRD). Optical transmittance was measured in UV-VIS regions with the result that the transmittance is 82.6% at a wavelength of 800 nm.

  10. 1-Benzylimidazolium hexafluorophosphate–1-benzylimidazole (1/1

    Directory of Open Access Journals (Sweden)

    Qing-Xiang Liu

    2008-02-01

    Full Text Available In the title compound, C10H11N2+·PF6−·C10H10N2, the H atom involved in protonation is disordered equally between the cation and the neutral molecule. The dihedral angle between the phenyl and imidazole rings is 82.6 (2°. In the crystal structure, there are head-to-tail π–π stacking interactions between imidazole rings; the interplanar separation is 3.295 (1 Å and the centroid–centroid separation is 3.448 (3 Å. In the centrosymmetric anion, two F atoms are disordered over two positions; the refined site-occupancy factors are 0.855 (11 and 0.145 (11.

  11. LGMD2I in a North American population

    Directory of Open Access Journals (Sweden)

    White Alexander J

    2007-11-01

    Full Text Available Abstract Background There is a marked variation in clinical phenotypes that have been associated with mutations in FKRP, ranging from severe congenital muscular dystrophies to limb-girdle muscular dystrophy type 2I (LGMD2I. Methods We screened the FKRP gene in two cohorts totaling 87 patients with the LGMD phenotype. Results The c.826C>A, p.L276I mutation was present in six patients and a compound heterozygote mutation in a seventh patient. Six patients had a mild LGMD2I phenotype, which resembles that of Becker muscular dystrophy. The other patient had onset before the age of 3 years, and thus may follow a more severe course. Conclusion These findings suggest that LGMD2I may be common in certain North American populations. This diagnosis should be considered early in the evaluation of LGMD.

  12. Dicty_cDB: Contig-U16139-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available urula pCMV... 64 4e-10 3 ( FF424278 ) G142P60001RH8.T0 Acorn worm juvenile pCMVSport6 l... 64 4e-10 3 ( FF43...5400 ) G142P60191RB9.T0 Acorn worm juvenile pCMVSport6 l... 64 4e-10 3 ( FF432476... ) G142P60148RH8.T0 Acorn worm juvenile pCMVSport6 l... 64 4e-10 3 ( FF658527 ) G826P5287RF4.T0 Acorn worm n...10 3 ( FF424605 ) G142P60022RH2.T0 Acorn worm juvenile pCMVSport6 l... 64 4e-10 3... ( FF434666 ) G142P60181RH2.T0 Acorn worm juvenile pCMVSport6 l... 64 4e-10 3 ( AF310884 ) Dictyostelium dis

  13. Dicty_cDB: Contig-U13534-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available orm blastula/gastrula pC... 46 9e-07 2 ( FF429725 ) G142P60109RH11.T0 Acorn worm juvenile pCMVSport6 ... 46 ....T0 Acorn worm blastula/gastrula pC... 46 9e-07 2 ( FF438333 ) G142P60231RB7.T0 Acorn worm juvenile pCMVSport...6 l... 46 9e-07 2 ( FF429920 ) G142P60112RD10.T0 Acorn worm juvenile pCMVSport6 ...2P60075RD9.T0 Acorn worm juvenile pCMVSport6 l... 46 9e-07 2 ( FF656315 ) G826P5273RD6.T0 Acorn worm normali...zed juvenile pE... 46 9e-07 2 ( FF437289 ) G142P60215RE1.T0 Acorn worm juvenile pCMVSport

  14. 磺酸树脂催化合成尼泊金酯的研究%Synthesis of Parabens Catalyzed by Sulfoacid Resin

    Institute of Scientific and Technical Information of China (English)

    曾立华; 李其华; 雷春华; 尹笃林

    2007-01-01

    以对羟基苯甲酸(PHBA)和丁醇为原料,用磺酸树脂作催化剂,催化合成了尼泊金丁酯,优化反应条件为:n(丁醇):n(对羟基苯甲酸)=5:1,催化剂磺酸树脂的用量为对羟基苯甲酸质量的21%,反应温度为回流温度,反应时间为5 h.尼泊金丁酯收率可达82.6%,催化剂可重复使用,产品结构用红外光谱图进行了表征.该方法也适合于合成尼泊金戊酯.

  15. Obstetric conditions and risk of first admission with schizophrenia: A Danish national register based study

    DEFF Research Database (Denmark)

    Byrne, Majella; Agerbo, Esben; Bennedsen, Birgit;

    2007-01-01

    -control study based on Danish longitudinal registers was conducted to investigate the risk of schizophrenia associated with exposure to a range of obstetric events. The sample included 1039 first admissions to, or contacts with Danish psychiatric services with an ICD-8 or ICD-10 diagnosis of schizophrenia...... and 24, 826 individually matched controls. Adjusting for the other obstetric factors, family psychiatric history, and socio-economic and demographic factors, risk of schizophrenia was associated with maternal non-attendance at antenatal appointments (Incidence Rate Ratio (IRR) 2.08, 95% CI: 1.0, 4...... (IRR 2.15, 95% CI: 1.1, 4.4), and maternal sepsis of childbirth and the puerperium (IRR 2.91, 95% CI: 1.1, 7.9). There was no significant interaction between the obstetric factors and either sex or family psychiatric history. The data suggest a modest association between prematurity, indicators...

  16. The application of evidence-based nursing in preventing complications occurred after interventional treatment of primary liver cancer

    International Nuclear Information System (INIS)

    Objective: To investigate the clinical effect of evidence-based nursing in preventing complications occurred after interventional treatment of primary liver cancer. Methods: Fifty-four patients of primary liver cancer who had received hepatic arterial chemo embolization were enrolled in this study. Using evidence-based thinking, the author analyzed the causes of complications occurred after the interventional treatment, formulated scientific nursing countermeasures and adopted foreseeable nursing care. Results: Through timely observation and targeted care, the incidence of complications after interventional treatment was effectively reduced, moreover, the patient's rehabilitation was improved. Conclusion: For the prevention of complications occurred after interventional treatment in patients with primary liver cancer, the evidencebased nursing plays an important role. It can provide scientific guidance to nursing practice, improve the quality and efficiency of nursing and enhance the ability of nurses in solving clinical problems. (J Intervent Radiol, 2010, 19 : 824-826) (authors)

  17. Características físico-químicas e sensoriais da carne de cordeiros terminados com dietas contendo cana-de-açúcar ou silagem de milho e dois níveis de concentrado Physic-chemical and sensorial characteristics of meat from lambs finished with diets containing sugar cane or corn silage and two levels of concentrate

    Directory of Open Access Journals (Sweden)

    André Gustavo Leão

    2012-05-01

    Full Text Available Com o objetivo de avaliar as características físico-químicas e sensoriais da carne de cordeiros terminados em confinamento com dietas contendo cana-de-açúcar ou silagem de milho em duas relações volumoso:concentrado, 60:40 ou 40:60, utilizaram-se 32 cordeiros Ile de France, não-castrados, com 15 kg de peso corporal. Os animais foram confinados em baias individuais e abatidos aos 32 kg. As dietas e os músculos estudados não influenciaram o pH aos 45 minutos (6,56 e 24 horas (5,62 após o abate nem a capacidade de retenção de água (58,38% e a perda de peso por cocção (34,04%. A cor da carne e da gordura subcutânea não diferiu entre as dietas, entretanto a cor da carne variou entre os músculos longissimus lumborum e triceps brachii. A força de cisalhamento (1,85 kgf/cm² não foi afetada pelas dietas, porém diferiu entre os músculos, com valores de 1,41 e 2,28 kgf/cm² para o longissimus lumborum e triceps brachii, respectivamente. Nas análises sensoriais do lombo e da paleta, foram obtidas para os cordeiros alimentados com cana-de-açúcar e maior quantidade de concentrado as maiores notas para sabor (8,07 e 8,26, textura (8,53 e 8,53, preferência (8,20 e 8,46 e aceitação (8,33 e 8,26, respectivamente. A cana-de-açúcar na alimentação de cordeiros em confinamento manteve a qualidade físicoquímica da carne, podendo ser utilizada nesta fase de produção e, quando associada a maior quantidade de concentrado na dieta, melhora a qualidade sensorial da carne de cordeiros.With the objective of evaluating physic-chemical and sensorial characteristics of meat from lambs finished in feedlot with diets containing sugar cane or corn silage at two roughage:concentrate ratios, 60:40 or 40:60, 32 non-castrated Ile de France lambs, with 15 kg body weight were used. Animals were confined in individual stalls and were slaughtered at 32 kg body weight. Studied diets and muscles did not affect pH at 45 minutes (6.56 and 24 hours (5

  18. NOD2/CARD15 genotype and common gastrointestinal diseases in 43 600 individuals

    DEFF Research Database (Denmark)

    Yazdanyar, S.; Nordestgaard, B.G.

    2010-01-01

    appendicitis, 646 irritable bowel syndrome, 1301 infectious diseases of the gastrointestinal tract, 681 anal fissure, fistula and abscess, 826 gastrointestinal cancer and 161 developed cancer in liver and pancreas. Results. Some 89% were non-carriers, 11% heterozygotes, 0.15% homozygotes and 0.23% compound...... heterozygotes. Cumulative incidences differed by genotype for appendicitis (log-rank P = 0.02), anal fissure, fistula and abscess (P = 0.003) and gastrointestinal cancer (P = 0.004), but not for any of the other endpoints. Compared with non-carriers, age and sex adjusted hazard ratios were 2.7 (95% CI 1.......4-5.5) for appendicitis amongst compound heterozygotes, 3.2 (1.3-7.8) for anal fissure, fistula and abscess amongst compound heterozygotes, and 3.8 (1.6-9.2) for gastrointestinal cancer amongst homozygotes, whilst other genotypes did not have increased risk. The increased risk of gastrointestinal cancer amongst...

  19. ISOLATION AND PURIFICATION OF ALKALOIDS FROM PLUMULA NELUMBINIS BY DOUBLE-COLUMN ADSORPTION CHROMOTOGRAPHY

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jixiang; GUO Jinsheng; OU Lailiang

    2007-01-01

    The performance of adsorption and separation for liensinine, isoliensinine and neferine was studied by double-column adsorption chromatography using macroporous adsorption and cation exchange resins. The alkaloid extract with 49.2% total contents by mass representing 10.6% liensinine, 10.6% isoliensinine and 28.0% neferine respectively was prepared by D72 cation exchange resins, in which most of the impurities were water-soluble alkaloids. Furthermore, the alkaloid extract with 82.6% total contents by mass containing 33.1%, 15.0% and 34.5% of the three adsorbates respectively was prepared by double-column adsorption chromatography using AKS-W macroporous adsorption and D72 cation exchange resins. As a result, the content of single and total alkaloids has been greatly increased by the double-column adsorption chromatography.

  20. ISOLATION AND PURIFICATION OF ALKALOIDS FROM PLUMULA NELUMBINIS BY DOUBLE-COLUMN ADSORPTION CHROMOTOGRAPHY

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The performance of adsorption and separation for liensinine, isoliensinine and neferine was studied by double-column adsorption chromatography using macroporous adsorption and cation exchange resins. The alkaloid extract with 49.2% total contents by mass representing 10.6% liensinine, 10.6% isoliensinine and 28.0% neferine respectively was prepared by D72 cation exchange resins, in which most of the impurities were water-soluble alkaloids. Furthermore,the alkaloid extract with 82.6% total contents by mass containing 33.1%, 15.0% and 34.5% of the three adsorbates respectively was prepared by double-column adsorption chromatography using AKS-W macroporous adsorption and D72 cation exchange resins. As a result, the content of single and total alkaloids has been greatly increased by the double-column adsorption chromatography.

  1. Determination of the seroprevalence of Newcastle disease virus (avian paramyxovirus type 1 in Zambian backyard chicken flocks

    Directory of Open Access Journals (Sweden)

    Chimuka Musako

    2012-02-01

    Full Text Available A cross-sectional study was conducted in five provinces and 11 districts of Zambia to determine the seroprevalence of Newcastle disease in Zambian backyard chicken flocks. Of the chickens sampled, 73.9% tested positive for avian paramyxovirus type 1 antibodies by means of an enzyme-linked immunosorbent assay. Seroprevalence varied amongst the five provinces sampled, ranging from 82.6% in the Eastern Province to 48.3% in Luapula Province. Seroprevalence also varied amongst the 11 districts sampled, ranging from 91.3% in Monze district of Southern Province to 22.8% in Mufulira district of the Copperbelt province. Overall, the seroprevalence of Newcastle disease in Zambian backyard chicken flocks has increased since the previous study conducted in 1994.

  2. Identity processes and statuses in post-Soviet Georgia: Exploration processes operate differently.

    Science.gov (United States)

    Skhirtladze, Nino; Javakhishvili, Nino; Schwartz, Seth J; Beyers, Wim; Luyckx, Koen

    2016-02-01

    Identity formation is one of the main developmental tasks of emerging adulthood. Based on quantitative data on a five-dimensional model of identity formation, we concluded that the identity formation process has some different features in the Republic of Georgia than it does in many Western countries. Results obtained from young Georgian adults (N = 295, 82.6% female) yielded four exploration processes instead of three, which is in line with the recent Swiss findings. A key difference between Georgia and the Western contexts, however, is that exploration in breadth is highly correlated with ruminative exploration. Cluster analysis, which produced six identity clusters, also supported this pattern. Achievement, the most adjusted cluster in Western contexts, was relatively low on exploration in breadth. We discuss ways in which the Georgian transition from Soviet communism to a more globalized society may contribute to limited opportunities for identity exploration and may add some tension to the identity development process.

  3. Screening of 33 Medicinal Plants for the Microelements Content

    Directory of Open Access Journals (Sweden)

    Ducu Sandu Ştef

    2010-05-01

    Full Text Available The microelements content of 33 medicinal plants was analyzed. The analysed microelements were: Iron, copper, zinc, manganese, cobalt, chromium, nickel, cadmium and lead. Mineral contents were determinate by flame atomic absorption spectrometry (F-AAS with high resolution continuum source ContrAA 300 spectrometer. The contents in microelements for analysed samples were in range: 18.1 ppm (Symphytum officinale - 1.4 ppm (Rhamnus frangula, for Copper; 26,2 ppm (Valeriana officinalis – 4,3 ppm (Rhamnus frangula, for Zinc; 214 ppm. (Violae tricoloris herba - 18 ppm (Equisetum arvense, for Manganese; 826 ppm (Calendula officinalis - 23 ppm (Rhamnus frangula, for Iron. The microelements contents (Cu, Zn, Mn, Fe, Co, Cr, Ni, Cd and Pb have grouped the analyzed medicinal plants in two main clusters. First main cluster was formed by other two groups.

  4. Dicty_cDB: SSC760 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSC760 (Link to dictyBase) - - - Contig-U16310-1 SSC760Z (Link... to Original site) - - SSC760Z 608 - - - - Show SSC760 Library SS (Link to library) Clone ID SSC760 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SS/SSC7-C/SSC760Q.Seq.d/ Representative seq. ID SSC76...0Z (Link to Original site) Representative DNA sequence >SSC760 (SSC760Q) /CSM/SS/SSC7-C/SSC760Q.Seq.d/ XXXXX...92020 ) Dictyostelium discoideum slug cDNA, clone SSC826. 1035 0.0 1 dna update 2009. 7.10 Homology vs Prote

  5. Salmonella-Typhimurium phage types from human salmonellosis in denmark 1988 to 1993

    DEFF Research Database (Denmark)

    Wegener, Henrik Caspar; Baggesen, Dorte Lau; Gaarslev, K.

    1994-01-01

    and 194. It is concluded that phage typing, although here performed retrospectively, produces valuable epidemiological information regarding changes in the relative importance of different sources of infection in humans. It is suggested that phage typing be performed prospectively on both human and animal......A total of 989 isolates of Salmonella enterica ssp. enterica serovar Typhimurium from cases of human salmonellosis were investigated by phage typing, The isolates comprised all isolates recovered during the month of August in each of the years from 1988 to 1993. Phage typing assigned 82.......6% of the strains to 36 different definitive types, 11.9% of the strains belonged to types of unknown lysis pattern (RDNC), and 5.5% could not be typed by the phages used (NT). Three phage types (12, 66 and 110) made up approximately 50% of the isolates in each of the years investigated. During the period...

  6. Robustness of time frequency distribution based features for automated neonatal EEG seizure detection.

    Science.gov (United States)

    Nagaraj, S B; Stevenson, N J; Marnane, W P; Boylan, G B; Lightbody, G

    2014-01-01

    In this paper we examined the robustness of a feature-set based on time-frequency distributions (TFDs) for neonatal EEG seizure detection. This feature-set was originally proposed in literature for neonatal seizure detection using a support vector machine (SVM). We tested the performance of this feature-set with a smoothed Wigner-Ville distribution and modified B distribution as the underlying TFDs. The seizure detection system using time-frequency signal and image processing features from the TFD of the EEG signal using modified B distribution was able to achieve a median receiver operator characteristic area of 0.96 (IQR 0.91-0.98) tested on a large clinical dataset of 826 h of EEG data from 18 full-term newborns with 1389 seizures. The mean AUC was 0.93. PMID:25570580

  7. Análise das modificações vocais de repórteres na situação de ruído Analysis of reporters' vocal changes in the presence of noise

    Directory of Open Access Journals (Sweden)

    Cristina Ribeiro Paiva Caldeira

    2012-01-01

    Full Text Available OBJETIVO: Verificar e comparar a ocorrência das modificações vocais de repórteres e não-repórteres na presença de ruído mascarante. MÉTODOS:Participaram 46 sujeitos, sendo 23 repórteres e 23 não-repórteres (grupo controle, todos com audição normal. Os participantes deveriam ler um trecho de uma matéria de telejornal em três situações de escuta: sem ruído mascarante, com ruído de 50 dB, e com ruído de 90 dB. As narrações foram gravadas e submetidas à avaliação perceptivo-auditiva (realizada por uma fonoaudióloga especialista em voz e análise acústica (medidas extraídas por meio do Software Voxmetria - CTS Informática. RESULTADOS: Com 50 dB de mascaramento, houve maior aumento nos parâmetros pitch (82,6%, loudness (91,3% e tensão (82,6% no grupo controle, quando este foi comparado ao grupo dos repórteres. O mesmo ocorreu com ruído de 90 dB para os parâmetros pitch (95,7%, loudness (100% e tensão (91,3%. CONCLUSÃO: As consequências negativas do efeito Lombard ocorrem em ambos os grupos, porém, pelas respostas apresentadas, os repórteres demonstram conseguir inibir parcialmente o impacto negativo das situações de ruído, por provável estabilidade da emissão profissional e ativação de outras vias de monitoramento.PURPOSE: To investigate and compare the occurrence of vocal changes in the presence of masking noise between reporters and other professionals. METHODS: Participants were 46 subjects with normal hearing, 23 reporters (study group and 23 non-reporters (control group. Participants read an excerpt from a TV news broadcast in three listening situations: without masking noise, with 50 dB white noise, and with 90 dB white noise. The narrations were recorded and then submitted to auditory-perceptual and acoustic analyses. The auditory-perceptual analysis was performed by a speech-language pathologist specialized in voice. The acoustic analysis used the software Voxmetria (CTS Informática to perform

  8. Production and Decay of (Q Q Qbar Qbar) States

    CERN Document Server

    Karliner, Marek; Nussinov, Shmuel

    2016-01-01

    The question of whether there exist bound states of two heavy quarks $Q=(c,b)$ and antiquarks $\\bar Q = (\\bar c, \\bar b)$, distinct from a pair of quark-antiquark mesons, has been debated for more than forty years. We suggest some means of producing and observing $Q_1 Q_2 \\bar Q_3 \\bar Q_4$ resonant states, concentrating on the $c c \\bar c \\bar c$ channel which is most easily produced and the $b b \\bar b \\bar b$ channel which has a better chance of being relatively narrow. We obtain $M_{(cc)(\\bar c \\bar c)} = 6,192 \\pm 25$ MeV and $M_{(bb)(\\bar b \\bar b)} = 18,826 \\pm 25$ MeV, for the charmed and bottom tetraquarks, respectively. Experimental search for these states in the relevant mass region is highly desirable.

  9. Detection of a low-eccentricity and super-massive planet to the subgiant HD 38801

    CERN Document Server

    Harakawa, Hiroki; Fischer, Debra A; Ida, Shigeru; Omiya, Masashi; Johnson, John A; Marcy, Geoffrey W; Toyota, Eri; Hori, Yasunori; Howard, Andrew W

    2010-01-01

    We report the detection of a large mass planet orbiting around the K0 metal-rich subgiant HD38801 ($V=8.26$) by precise radial velocity (RV) measurements from the Subaru Telescope and the Keck Telescope. The star has a mass of $1.36M_{\\odot}$ and metallicity of [Fe/H]= +0.26. The RV variations are consistent with a circular orbit with a period of 696.0 days and a velocity semiamplitude of 200.0\\mps, which yield a minimum-mass for the companion of $10.7\\mjup$ and semimajor axis of 1.71 AU. Such super-massive objects with very low-eccentricities and hundreds of days period are uncommon among the ensemble of known exoplanets.

  10. Synthesis and structural characterization of a new layered chlorozincophosphate, Zn(HPO4)Cl·[H3N(CH2)6NH3]0.5

    International Nuclear Information System (INIS)

    A new layered zinc-phosphate Zn(HPO4)Cl·[H3N(CH2)6NH3]0.5 was synthesized in acidic conditions at room temperature. It crystallizes in monoclinic space group C2/c (No. 15) with the lattice parameters a=21.826(3) A, b=9.452(7) A, c=8.780(1) A, β=109.36(8) deg., V=1708.83(1) A3, Z=8, R=0.036, Rw=0.047. The structure of this compound is determined by X-ray diffraction and characterized with IR, TGA-DTA/DSC and NMR. The structure consists of inorganic layers, built by PO4 and ZnO3Cl tetrahedra interconnected by common oxygen atoms. The organic entities, located between these layers, perform the 3D cohesion through N-H···O or N-H···Cl hydrogen bonds

  11. Stereotactic radiotherapy (SRT) for acoustic neuroma by linear accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Sakamoto, Tooru; Shirato, Hiroki; Fukuda, Satoshi [Hokkaido Univ., Sapporo (Japan). School of Medicine] [and others

    1997-10-01

    We analyzed forty one patients with acoustic neuroma treated by SRT giving 36 Gy in 20 fractions to 48 Gy in 23 fractions during 1991 and 1997, and found a sterilization of tumor size in 97.6%. Twenty-six patients had measurable hearing before and after SRT and 43.5% of patients showed change in pure tone average less than 10 dB, 82.6% less than 20 dB at the last follow-up examination. Facial and trigeminal nerve function was evaluated in 41 patients. Transient facial weakness developed in 4.8% and trigeminal neuropathy in 9.6% of irradiated cases. We consider that SRT complications are less than that of gamma-knife, although the longer follow-up period should be needed. (author)

  12. Enhancement of polycrystalline silicon solar cells efficiency using indium nitride particles

    International Nuclear Information System (INIS)

    In this work, we present a hybrid indium nitride particle/polycrystalline silicon solar cell based on 230 nm size indium nitride particles (InN-Ps) obtained through laser ablation. The solar cell performance measurements indicate that there is an absolute 1.5% increase (Δη) in the overall solar cell efficiency due to the presence of InN-Ps. Within the spectral range 300–1100 nm, improvements of up to 8.26% are observed in the external quantum efficiency (EQE) and increases of up to 8.75% are observed in the internal quantum efficiency (IQE) values of the corresponding solar cell. The enhancement in power performance is due to the down-shifting properties of the InN-Ps. The electrical measurements are supplemented by TEM, Raman, UV/VIS and PL spectroscopy of the InN-Ps. (paper)

  13. Human placental growth hormone, insulin-like growth factor I and -II, and insulin requirements during pregnancy in type 1 diabetes

    DEFF Research Database (Denmark)

    Fuglsang, Jens; Lauszus, Finn; Flyvbjerg, Allan;

    2003-01-01

    Human placental GH (hPGH) replaces pituitary GH during pregnancy. hPGH is correlated to serum IGF-I in normal pregnancies and in pregnancies complicated by fetoplacental disorders. In gestational diabetes and type 2 diabetes no correlation between hPGH and IGF-I has been found. The relationship...... between hPGH and IGF-I in type 1 diabetes mellitus has not been investigated thoroughly. Furthermore, hPGH may be involved in the development of insulin resistance during pregnancy. In this prospective, longitudinal study, 51 type 1 diabetic subjects were followed with repeated blood sampling during...... pregnancy (median, 14 blood samples/subject; range, 8-26). Maternal concentrations of serum hPGH, IGF-I, and IGF-II were measured and compared with insulin requirements and birth characteristics. hPGH was detected from as early as 6 wk gestation. In all subjects, a rise in serum hPGH was observed during...

  14. Searches for Neutral Higgs Bosons in $e^+ e^-$ Collisions around $\\sqrt{s}$ = 189 GeV

    CERN Document Server

    Abreu, P; Adye, T; Adzic, P; Albrecht, Z; Alderweireld, T; Alekseev, G D; Alemany, R; Allmendinger, T; Allport, P P; Almehed, S; Amaldi, Ugo; Amapane, N; Amato, S; Anassontzis, E G; Andersson, P; Andreazza, A; Andringa, S; Antilogus, P; Apel, W D; Arnoud, Y; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Bambade, P; Barão, F; Barbiellini, Guido; Barbier, R; Bardin, Dimitri Yuri; Barker, G; Baroncelli, A; Battaglia, Marco; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Beillière, P; Belokopytov, Yu A; Belous, K S; Benekos, N C; Benvenuti, Alberto C; Bérat, C; Berggren, M; Bertini, D; Bertrand, D; Besançon, M; Bigi, M; Bilenky, S M; Bizouard, M A; Bloch, D; Blom, H M; Bonesini, M; Boonekamp, M; Booth, P S L; Borgland, A W; Borisov, G; Bosio, C; Botner, O; Boudinov, E; Bouquet, B; Bourdarios, C; Bowcock, T J V; Boyko, I; Bozovic, I; Bozzo, M; Bracko, M; Branchini, P; Brenner, R A; Brückman, P; Brunet, J M; Bugge, L; Buran, T; Buschbeck, Brigitte; Buschmann, P; Cabrera, S; Caccia, M; Calvi, M; Camporesi, T; Canale, V; Carena, F; Carroll, L; Caso, Carlo; Castillo-Gimenez, M V; Cattai, A; Cavallo, F R; Chabaud, V; Chapkin, M M; Charpentier, P; Chaussard, L; Checchia, P; Chelkov, G A; Chierici, R; Shlyapnikov, P; Chochula, P; Chorowicz, V; Chudoba, J; Cieslik, K; Collins, P; Contri, R; Cortina, E; Cosme, G; Cossutti, F; Crawley, H B; Crennell, D J; Crépé, S; Crosetti, G; Cuevas-Maestro, J; Czellar, S; Dalmau, J; Davenport, Martyn; Da Silva, W; Della Ricca, G; Delpierre, P A; Demaria, N; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Min, A; De Paula, L S; Dijkstra, H; Di Ciaccio, Lucia; Dolbeau, J; Doroba, K; Dracos, M; Drees, J; Dris, M; Duperrin, A; Durand, J D; Eigen, G; Ekelöf, T J C; Ekspong, G; Ellert, M; Elsing, M; Engel, J P; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Fayot, J; Feindt, M; Ferrer, A; Ferrer-Ribas, E; Ferro, F; Fichet, S; Firestone, A; Flagmeyer, U; Föth, H; Fokitis, E; Fontanelli, F; Franek, B J; Frodesen, A G; Frühwirth, R; Fulda-Quenzer, F; Fuster, J A; Galloni, A; Gamba, D; Gamblin, S; Gandelman, M; García, C; Gaspar, C; Gaspar, M; Gasparini, U; Gavillet, P; Gazis, E N; Gelé, D; Ghodbane, N; Gil, I; Glege, F; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; González-Caballero, I; Gopal, G; Gorn, L; Guz, Yu; Gracco, Valerio; Grahl, J; Graziani, E; Gris, P; Grosdidier, G; Grzelak, K; Guy, J; Hahn, F; Hahn, S; Haider, S; Hallgren, A; Hamacher, K; Hansen, J; Harris, F J; Hedberg, V; Heising, S; Hernández, J J; Herquet, P; Herr, H; Hessing, T L; Heuser, J M; Higón, E; Holmgren, S O; Holt, P J; Hoorelbeke, S; Houlden, M A; Hrubec, Josef; Huber, M; Huet, K; Hughes, G J; Hultqvist, K; Jackson, J N; Jacobsson, R; Jalocha, P; Janik, R; Jarlskog, C; Jarlskog, G; Jarry, P; Jean-Marie, B; Jeans, D; Johansson, E K; Jonsson, P; Joram, C; Juillot, P; Jungermann, L; Kapusta, F; Karafasoulis, K; Katsanevas, S; Katsoufis, E C; Keränen, R; Kernel, G; Kersevan, Borut P; Khokhlov, Yu; Khomenko, B A; Khovanskii, N N; Kiiskinen, A P; King, B J; Kinvig, A; Kjaer, N J; Klapp, O; Klein, H; Kluit, P; Kokkinias, P; Kostyukhin, V; Kourkoumelis, C; Kuznetsov, O; Krammer, M; Kriznic, E; Krumshtein, Z; Kubinec, P; Kurowska, J; Kurvinen, K L; Lamsa, J; Lane, D W; Lapin, V; Laugier, J P; Lauhakangas, R; Leder, G; Ledroit, F; Lefébure, V; Leinonen, L; Leisos, A; Leitner, R; Lemonne, J; Lenzen, G; Lepeltier, V; Lesiak, T; Lethuillier, M; Libby, J; Liebig, W; Liko, D; Lipniacka, A; Lippi, I; Lörstad, B; Loken, J G; Lopes, J H; López, J M; López-Fernandez, R; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Mahon, J R; Maio, A; Malek, A; Malmgren, T G M; Maltezos, S; Malychev, V; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Martínez-Vidal, F; Martí i García, S; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Matthiae, Giorgio; Mazzucato, F; Mazzucato, M; McCubbin, M L; McKay, R; McNulty, R; McPherson, G; Meroni, C; Meyer, W T; Myagkov, A; Migliore, E; Mirabito, L; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Møller, R; Mönig, K; Monge, M R; Moreau, X; Morettini, P; Morton, G; Müller, U; Münich, K; Mulders, M; Mulet-Marquis, C; Muresan, R; Murray, W J; Muryn, B; Myatt, Gerald; Myklebust, T; Naraghi, F; Nassiakou, M; Navarria, Francesco Luigi; Navas, S; Nawrocki, K; Negri, P; Neufeld, N; Nicolaidou, R; Nielsen, B S; Niezurawski, P; Nikolenko, M; Nomokonov, V P; Nygren, A; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, Risto; Orazi, G; Österberg, K; Ouraou, A; Paganoni, M; Paiano, S; Pain, R; Paiva, R; Palacios, J; Palka, H; Papadopoulou, T D; Papageorgiou, K; Pape, L; Parkes, C; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Pavel, T; Pegoraro, M; Peralta, L; Pernicka, Manfred; Perrotta, A; Petridou, C; Petrolini, A; Phillips, H T; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Pol, M E; Polok, G; Poropat, P; Pozdnyakov, V; Privitera, P; Pukhaeva, N; Pullia, Antonio; Radojicic, D; Ragazzi, S; Rahmani, H; Rames, J; Ratoff, P N; Read, A L; Rebecchi, P; Redaelli, N G; Regler, Meinhard; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Resvanis, L K; Richard, F; Rídky, J; Rinaudo, G; Ripp-Baudot, I; Rohne, O; Romero, A; Ronchese, P; Rosenberg, E I; Rosinsky, P; Roudeau, Patrick; Rovelli, T; Royon, C; Ruhlmann-Kleider, V; Ruiz, A; Saarikko, H; Sacquin, Yu; Sadovskii, A; Sajot, G; Salt, J; Sampsonidis, D; Sannino, M; Schwemling, P; Schwering, B; Schwickerath, U; Scuri, F; Seager, P; Sedykh, Yu; Segar, A M; Seibert, N; Sekulin, R L; Shellard, R C; Siebel, M; Simard, L C; Simonetto, F; Sissakian, A N; Smadja, G; Smirnova, O G; Smith, G R; Solovyanov, O; Sopczak, A; Sosnowski, R; Spassoff, Tz; Spiriti, E; Squarcia, S; Stanescu, C; Stanic, S; Stanitzki, M; Stevenson, K; Stocchi, A; Strauss, J; Strub, R; Stugu, B; Szczekowski, M; Szeptycka, M; Tabarelli de Fatis, T; Taffard, A C; Tegenfeldt, F; Terranova, F; Thomas, J; Timmermans, J; Tinti, N; Tkatchev, L G; Tobin, M; Todorova, S; Tomaradze, A G; Tomé, B; Tonazzo, A; Tortora, L; Tortosa, P; Tranströmer, G; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tzamarias, S; Ullaland, O; Uvarov, V; Valenti, G; Vallazza, E; Van der Velde, C; van Dam, P; Van den Boeck, W; Van Doninck, W K; Van Eldik, J; Van Lysebetten, A; Van Remortel, N; Van Vulpen, I B; Vegni, G; Ventura, L; Venus, W A; Verbeure, F; Verlato, M; Vertogradov, L S; Verzi, V; Vilanova, D; Vitale, L; Vlasov, E; Vodopyanov, A S; Voulgaris, G; Vrba, V; Wahlen, H; Walck, C; Washbrook, A J; Weiser, C; Wicke, D; Wickens, J H; Wilkinson, G R; Winter, M; Witek, M; Wolf, G; Yi, J; Yushchenko, O P; Zalewska-Bak, A; Zalewski, Piotr; Zavrtanik, D; Zevgolatakos, E; Zimin, N I; Zinchenko, A I; Zoller, P; Zucchelli, G C; Zumerle, G

    2000-01-01

    Searches for neutral Higgs bosons in the Standard Model and the MSSM havebeen performed using data collected by the DELPHI experiment at acentre-of-mass energy of 188.7 GeV, corresponding toan integrated luminosity of 158~pb$^{-1}$.These analyses are used, in combination with our results from lowerenergies, to set new 95\\% confidence level lower mass bounds on theStandard Model Higgs boson (94.6 GeV/$c^2$) and on the lightest neutralscalar (82.6 GeV/$c^2$) and neutral pseudoscalar (84.1 GeV/$c^2$) Higgsbosons in a representative scan of the MSSM parameters. The results are alsointerpreted in the framework of a general two-Higgs doublet model.

  15. Multi-level Clustering of Wear Particles Based on ANOVA-KW Test%基于ANOVA-KW检验的磨粒多级聚类分析

    Institute of Scientific and Technical Information of China (English)

    黄成; 王仲君; 潘岚; 吕植勇

    2010-01-01

    针对46个非正常磨粒样本形态参数数据进行分析,提出并确定多级聚类的思想以及具体实施步骤,然后通过对磨粒形态参数进行ANOVA-KW检验确定对磨粒分类有影响的参数变量,根据对确定的变量进行多级聚类分析,对球型、切削磨粒的识别度达到了95.6%,对疲劳、层状、片状磨粒的识别度达到了82.6%.

  16. Crystal structure of (E-4-(acetoxyimino-N-allyl-3-isopropyl-2,6-diphenylpiperidine-1-carbothioamide

    Directory of Open Access Journals (Sweden)

    T. Mohandas

    2015-08-01

    Full Text Available The title compound, C26H31N3O2S, crystallizes with two molecules (A and B in the asymmetric unit. In each case, the piperidine ring exists in a twist-boat conformation. The dihedral angle between the phenyl rings is 46.16 (12° in molecule A and 44.95 (12° in molecule B. In both molecules, the allyl side chain is disordered over two orientations in a 0.649 (9:0.351 (9 ratio for molecule A and 0.826 (10:0.174 (10 ratio for molecule B. In the crystal, neither molecule forms a hydrogen bond from its N—H group, presumably due to steric hindrance. A+A and B+B inversion dimers are formed, linked by pairs of weak C—H...O hydrogen bonds enclosing R22(22 ring motifs.

  17. Crystal structure of (E)-4-(acetoxyimino)-N-allyl-3-isopropyl-2,6-diphenylpiperidine-1-carbothioamide

    OpenAIRE

    Mohandas, T; K. Gokula Krishnan; Balamurugan, S.; Harrison, William T. A.; Thanikachalam, V.; Sakthivel, P.

    2015-01-01

    The title compound, C26H31N3O2S, crystallizes with two molecules (A and B) in the asymmetric unit. In each case, the piperidine ring exists in a twist-boat conformation. The dihedral angle between the phenyl rings is 46.16 (12)° in molecule A and 44.95 (12)° in molecule B. In both molecules, the allyl side chain is disordered over two orientations in a 0.649 (9):0.351 (9) ratio for molecule A and 0.826 (10):0.174 (10) ratio for molecule B. In the crystal, neither molecule forms a hydrogen bon...

  18. Crystal structure of (E)-4-(acet­oxy­imino)-N-allyl-3-isopropyl-2,6-di­phenyl­piperi­dine-1-carbo­thio­amide

    OpenAIRE

    Mohandas, T; Krishnan, K. Gokula; Balamurugan, S.; Harrison, William T. A.; Thanikachalam, V.; Sakthivel, P.

    2015-01-01

    The title compound, C26H31N3O2S, crystallizes with two mol­ecules (A and B) in the asymmetric unit. In each case, the piperidine ring exists in a twist-boat conformation. The dihedral angle between the phenyl rings is 46.16 (12)° in mol­ecule A and 44.95 (12)° in mol­ecule B. In both mol­ecules, the allyl side chain is disordered over two orientations in a 0.649 (9):0.351 (9) ratio for mol­ecule A and 0.826 (10):0.174 (10) ratio for mol­ecule B. In the crystal, neither mol­ecule forms a hydro...

  19. Use of inline measures of L-lactate dehydrogenase for classification of posttreatment mammary Staphylococcus aureus infection status in dairy cows

    DEFF Research Database (Denmark)

    Jørgensen, C. Hildebrandt; Kristensen, Anders Ringgaard; Østergaard, S.;

    2016-01-01

    Staphylococcus aureus infection from 4 herds collected in 2010. The uninfected data set came from 35 uninfected cows collected during 2013 from 2 herds. Bacteriological culturing was used as gold standard. To test the model, we collected data from the 48 infected cows 50 d after antibiotic treatment. As a result...... of the treatment, this test data set consisted of 25 cows that still had a subclinical infection and 23 cows that were recovered. Model sensitivity was 36.0% and specificity was 82.6%. To a large extent, L-lactate dehydrogenase reflected the cow's immune response to the presence of pathogens in the udder. However......, cows that were classified correctly before treatment had a better chance of correct classification after treatment. This indicated a variation between cows in immune response to subclinical mammary infection that may complicate the detection of subclinically infected cows and determination of recovery....

  20. Splenic sequestration of Tc-99m labeled heat treated red blood cells. [Feasibility of use for spleen imaging

    Energy Technology Data Exchange (ETDEWEB)

    Atkins, H L; Goldman, A G; Fairchild, R G; Oster, Z H; Som, P; Richards, P; Meinken, G E; Srivastava, S C

    1979-01-01

    The rate of blood clearance and spleen uptake as well as the total spleen uptake of heat damaged red blood cells labeled with Tc-99m was determined in eight patients, six of whom had chronic lymphatic leukemia, one had polycythemia vera and one had eosinophilia of unknown origin. Spleen uptake at 2 hrs was 72.0 +- 18.5%. Approximately 82.6% of the initial radioactivity was cleared from the blood by 2 hrs with a rapid T 1/2 component of 6.3 +- 4.7 min. The T 1/2 of splenic uptake was 8.3 +- 4.6 min with a plateauing of splenic radioactivity by 30 min. The preliminary results indicate that the method of preparation is reliable but the usefulness of the method for evaluating spleen function remains to be determined.

  1. Cardiac Time Intervals Measured by Tissue Doppler Imaging M-mode

    DEFF Research Database (Denmark)

    Biering-Sørensen, Tor; Mogelvang, Rasmus; Schnohr, Peter;

    2016-01-01

    function was evaluated in 1915 participants by using both conventional echocardiography and tissue Doppler imaging (TDI). The cardiac time intervals, including the isovolumic relaxation time (IVRT), isovolumic contraction time (IVCT), and ejection time (ET), were obtained by TDI M-mode through the mitral...... leaflet. IVCT/ET, IVRT/ET, and myocardial performance index [MPI=(IVRT+IVCT)/ET] were calculated. After multivariable adjustment for clinical variables the IVRT, IVRT/ET, and MPI, remained significantly impaired in persons with hypertension (n=826) compared with participants without hypertension (n=1082......). Additionally, they displayed a significant dose-response relationship, between increasing severity of elevated blood pressure and increasing left ventricular mass index (P

  2. Does the use of laminar flow and space suits reduce early deep infection after total hip and knee replacement?: the ten-year results of the New Zealand Joint Registry.

    Science.gov (United States)

    Hooper, G J; Rothwell, A G; Frampton, C; Wyatt, M C

    2011-01-01

    We have investigated whether the use of laminar-flow theatres and space suits reduced the rate of revision for early deep infection after total hip (THR) and knee (TKR) replacement by reviewing the results of the New Zealand Joint Registry at ten years. Of the 51 485 primary THRs and 36 826 primary TKRs analysed, laminar-flow theatres were used in 35.5% and space suits in 23.5%. For THR there was a significant increase in early infection in those procedures performed with the use of a space suit compared with those without (p space suit (p space suit (p space suits were used in those theatres (p deep infection has not been reduced by using laminar flow and space suits. Our results question the rationale for their increasing use in routine joint replacement, where the added cost to the health system seems to be unjustified.

  3. Areva at March 31, 2016

    International Nuclear Information System (INIS)

    In the first quarter of 2016, AREVA generated consolidated revenue of 826 million euros, a decrease of 0.8% (-2.2% like for like) compared with the same period in 2015, due in particular to the schedule of uranium deliveries. Foreign exchange had a positive impact of 12 million euros over the period. At March 31, 2016, the group's backlog reached 33.6 billion euros, up sharply compared to December 31, 2015 (29 billion euros), and represented eight years of revenue. It reflects in particular multi-year commercial agreements signed with EDF in early 2016. The order intake for the first quarter of 2016 totaled 6.1 billion euros, a strong increase in relation to the first quarter of 2015 (0.3 billion euros)

  4. On 2-D Boussinesq equations for MHD convection with stratification effects

    Science.gov (United States)

    Bian, Dongfen; Gui, Guilong

    2016-08-01

    This paper is concerned with the two-dimensional magnetohydrodynamics-Boussinesq system with the temperature-dependent viscosity, thermal diffusivity and electrical conductivity. The first progress on this topic was made independently by Chae and Hou-Li [8,26] where the Boussinesq system with partial constant viscosity is obtained. Recently, Wang-Zhang [45] considered the temperature-dependent viscosity and thermal diffusivity, and Li-Xu [16] generalized the Wang-Zhang's result to the inviscid case with temperature-dependent thermal diffusivity. In this paper, we include the stratification and magnetic effects and consider the full system, in the framework of low regularity. We prove that, without any smallness assumption on the initial data, the full system is globally well-posed. Moreover, by applying the uniformly bounded generalized Oseen operator, time decay estimate of the solution is obtained.

  5. Gene discovery in Triatoma infestans

    Directory of Open Access Journals (Sweden)

    de Burgos Nelia

    2011-03-01

    Full Text Available Abstract Background Triatoma infestans is the most relevant vector of Chagas disease in the southern cone of South America. Since its genome has not yet been studied, sequencing of Expressed Sequence Tags (ESTs is one of the most powerful tools for efficiently identifying large numbers of expressed genes in this insect vector. Results In this work, we generated 826 ESTs, resulting in an increase of 47% in the number of ESTs available for T. infestans. These ESTs were assembled in 471 unique sequences, 151 of which represent 136 new genes for the Reduviidae family. Conclusions Among the putative new genes for the Reduviidae family, we identified and described an interesting subset of genes involved in development and reproduction, which constitute potential targets for insecticide development.

  6. TPX: Contractor preliminary design review. Volume 5, Manufacturing R&D

    Energy Technology Data Exchange (ETDEWEB)

    Roach, J.F.; Urban, W.M.; Hartman, D. [Everson Electric Co., Bekthlehem, PA (United States)

    1995-08-04

    TPX Insulation & Impregnation R&D test results are reported for 1x2 samples designed for screening candidate conduit insulation systems for TPX PF and TF coils. The epoxy/glass insulation system and three proposed alternate insulation systems employing Kapton, was evaluated in as received sample condition and after 10 thermal cycles in liquid nitrogen. Two DGBA impregnation systems, Shell 826 and CTD101K were investigated. Square incoloy 908 and 316 LN stainless hollow conduits were used for 1x2 sample fabrication. Capacitance, dielectric loss, and insulation resistance dielectric characteristics were measured for all samples. Partial discharge performance was measured for samples either in air, under silicon oil, or under liquid nitrogen up to 10kVrms at 60 Hz. Hipot screening was performed at 10 kVdc. The samples were cross sectioned and evaluated for impregnation quality. The implications of the test results on the TPX preliminary design decision are discussed.

  7. Supplement to dose conversion factors for air, water, soil and building materials

    International Nuclear Information System (INIS)

    The calculations described in the original report, AECL-9825, have been repeated on a more recent database obtained from Oak Ridge National Laboratories (US). This database was apparently derived from the Evaluated Nuclear Structure Data File (ENSDF) and was used as the basis for the preparation of ICRP publication number 38. Data for 826 nuclides are given, including Argon-42 which was added to the database manually. Because the new database is more detailed than that used previously, and the beta-spectrum calculation sub-routine was improved, these new calculations are believed to be more accurate than those in the original report. This report does not entirely replace the original version, however, since there are a few nuclides that were included in that report but not in the current one

  8. Quantitative evaluation of a handheld light microscope for field diagnosis of soil-transmitted helminth infection.

    Science.gov (United States)

    Bogoch, Isaac I; Andrews, Jason R; Speich, Benjamin; Ame, Shaali M; Ali, Said M; Stothard, J Russell; Utzinger, Jürg; Keiser, Jennifer

    2014-12-01

    We evaluated the Newton Nm1, a commercially available handheld light microscope and compared it with conventional light microscopy for the diagnosis of soil-transmitted helminth infections. A total of 91 Kato-Katz thick smears were examined by experienced microscopists and helminth eggs were counted and expressed as eggs per gram of stool (EPG). Mean egg counts were significantly higher with the conventional light microscope (5,190 EPG versus 2,386 EPG for Ascaris lumbricoides; 826 versus 456 for Trichuris trichiura; both P Newton Nm1 microscope may be a useful tool for the detection and quantification of soil-transmitted helminth infection in clinical, epidemiologic, and public health settings. PMID:25246697

  9. CO{sub 2}-recycling by plants: how reliable is the carbon isotope estimation?

    Energy Technology Data Exchange (ETDEWEB)

    Siegwolf, R.T.W.; Saurer, M. [Paul Scherrer Inst. (PSI), Villigen (Switzerland); Koerner, C. [Basel Univ., Basel (Switzerland)

    1997-06-01

    In the study of plant carbon relations, the amount of the respiratory losses from the soil was estimated, determining the gradient of the stable isotope {sup 13}C with increasing plant canopy height. According to the literature 8-26% of the CO{sub 2} released in the forests by soil and plant respiratory processes are reassimilated (recycled) by photosynthesis during the day. Our own measurements however, which we conducted in grass land showed diverging results from no indicating of carbon recycling, to a considerable {delta}{sup 13}C gradient suggesting a high carbon recycling rate. The role of other factors, such as air humidity and irradiation which influence the {delta}{sup 13}C in a canopy as well, are discussed. (author) 3 figs., 4 refs.

  10. Diagnostic Yield of High-Resolution Breast Sonography in Detecting Microcalcifications Compared to Mammography

    Directory of Open Access Journals (Sweden)

    N Ahmadinejad

    2009-08-01

    Full Text Available Background/Objective: Mammography remains the most suitable screening test in detecting microcalcifications as the earliest manifestation of breast malignancy. By means of highfrequency transducers yielding high-resolution breast imaging, some researchers have reported that ultrasonography is capable of depicting microcalcifications in the breast tissue. Therefore, this study has been designed to compare the diagnostic yield of high-resolution"nbreast ultrasonography (HRS versus conventional mammography."nPatients and Methods: Seventy-four consecutive patients who had breast microcalcifications (hyperdense foci < 0.5mm according to standard mammograms, without a prior history of breast disease, surgery, biopsy, chest wall radiation or systemic chemotherapy were enrolled. Considering mammograms as a reference, 46 patients without a mass, voluntarily underwent high-resolution bilateral breast ultrasonography."nResults: The mean age was 50.7±10 years (range, 35-85 years. The upper outer quadrant of the breast was the commonest place where microcalcifications were detected (36.9%. A relative frequency of 45.7% was reported for microcalcifications with breast imaging reporting"nand data system (BIRADS score 3. An overall 82.6% diagnostic yield was discovered for HRS in detecting microcalcifications; it detected all microcalcifications with BIRADS score 4 and 5, but 57.1% and 90.5% of microcalcifications with BIRADS score 2 and 3, respectively. Cluster microcalcification was the most common pattern (43.5%."nConclusion: Considering the 82.6% diagnostic yield of HRS compared to mammography, it can be proposed as the surrogate modality in locating microcalcifications in procedures such as biopsies and hook-wiring, with the advantage of reducing radiation exposure. HRS may be the future screening modality as a result of feasibility, safety, compliance and accuracy.

  11. 湖北野生香茶菜花期挥发油GC—MS分析%Analysis of Volatile Oil of Hubei Wild Rabdosia Amethystoides (Benth.) H. Hara in the Flower Period by GC-MS

    Institute of Scientific and Technical Information of China (English)

    梁利香; 陈琼; 陈利军

    2015-01-01

    目的:研究香茶菜花期挥发油的化学成分.方法:采用水蒸汽蒸馏法提取香茶菜花期的挥发油,以气相色谱—质谱联用(GC-MS)仪测定挥发油化学组分.结果:主要成分为2-甲氧基-4-乙烯基苯酚(33.076%),1,2,3,4-四甲基-5-亚甲基-1,3-环戊二烯(13.826%),2,3,4,6-四甲基苯酚(11.426%).结论:香茶菜含大量常用食品添加剂2-甲氧基-4-乙烯基苯酚,可以综合开发利用.%Objective:Studies on the chemical constituents of flower volatile oil from Rabdosia amethystoides (Benth.)H. Hara. Method:The essential oil was extracted from Rabdosia amethystoides (Benth.)H.Hara.by steam distillation. Compon-ents of the essential oils were analyzed by GC-MS. Result:The main chemical components are 2-Methoxy-4-vinylphenol (33.076%), 1,3-Cyclopentadiene, 1,2,3,4-tetramethyl-5-methylene-(13.826%), Phenol, 2,3,4,6-tetramethyl-(11.426%). Con-clusion:Rabdosia amethystoides (Benth.) H. Hara.contains a lot of 2-Methoxy-4-vinylphenol, which is a common food ad-ditives. Rabdosia amethystoides (Benth.) H. Hara.can be comprehensive utilization.

  12. Clinical and biochemical outcomes of men undergoing radical prostatectomy or radiation therapy for localized prostate cancer

    Energy Technology Data Exchange (ETDEWEB)

    Schreiber, David; Weiss, Jeffrey P.; Safdieh, Joseph; Weiner, Joseph; Rotman, Marvin; Schwartz, David [Veterans Affairs, New York Harbor Healthcare System, Brooklyn (United States); Rineer, Justin [University of Florida Health Cancer Center at Orlando Health, Orlando (United States)

    2015-03-15

    We analyzed outcomes of patients with prostate cancer undergoing either radical retropubic prostatectomy (RRP) +/- salvage radiation or definitive radiation therapy (RT) +/- androgen deprivation. From 2003-2010 there were 251 patients who underwent RRP and 469 patients who received RT (> or =7,560 cGy) for prostate cancer. Kaplan-Meier analysis was performed with the log-rank test to compare biochemical control (bCR), distant metastatic-free survival (DMPFS), and prostate cancer-specific survival (PCSS) between the two groups. The median follow-up was 70 months and 61.3% of the men were African American. For low risk disease the 6-year bCR were 90.3% for RT and 85.6% for RRP (p = 0.23) and the 6-year post-salvage bCR were 90.3% vs. 90.9%, respectively (p = 0.84). For intermediate risk disease the 6-year bCR were 82.6% for RT and 59.7% for RRP (p < 0.001) and 82.6% vs. 74.0%, respectively, after including those salvaged with RT (p = 0.06). For high risk disease, the 6-year bCR were 67.4% for RT and 41.3% for RRP (p < 0.001) and after including those salvaged with RT was 67.4% vs. 43.1%, respectively (p < 0.001). However, there were no significant differences between the two groups in regards to DMPFS or PCSS. Treatment approaches utilizing RRP +/- salvage radiation or RT +/- androgen deprivation yielded equivalent DMPFS and PCSS outcomes. Biochemical control rates, using their respective definitions, appeared equivalent or better in those who received treatment with RT.

  13. Synthesis and structure characterization of a new aromatic hydrazone%一种新型芳香酰腙的合成与结构表征

    Institute of Scientific and Technical Information of China (English)

    唐小冬; 郑长征; 田晓雪

    2011-01-01

    The title compound of l-(4-methoxyphenyl) ethanone 4-chlorob-en2oyl hydrazone was synthesized by the reaction of 4-methoxyphenyl ethyl ketone and 4-chlorobenzoyl hydrazine. The structure of the compound was characterized by elemental analysis and X-ray diffraction. It was assigned to orthorhombic crystal sy-stem, space group Pca2(l),cell data:a=0. 850 7(5)nm,a =90°,6 =0.557 1 (3)nm,£ = 90°, c = 3.215 4(18)nm,y = 90°,V = 1.523 9(14)nm3,Z=4,F(000) =632,/?, =0.031 7 [/ >2sigma(/)] ,wR2 =0.089 6. CCDC is 826 435.%目标化合物1-(4-甲氧基苯基)乙酮4-氯苯甲酰腙,由4-甲氧基苯基乙酮和4-氯苯甲酰肼通过脱水缩合反应制得,通过元素分析和X射线单晶衍射对目标化合物进行结构表征.检测数据表明,该新型酰腙为正交晶系,空间群为Pca2(1),晶胞学数据为α=0.850 7(5)nm,α=90°,b=0.557 1 (3) nm,β=90 °,c=3.215 4(18)nm,y=90°,V=1.523 9(14)nm3,Z =4,F(000)=632,R1 =0.031 7 [I>2sigma(I)],wR2=0.089 6.CCDC为826 435.

  14. 湖北野生香茶菜花期挥发油GC—MS分析%Analysis of Volatile Oil of Hubei Wild Rabdosia Amethystoides (Benth.) H. Hara in the Flower Period by GC-MS

    Institute of Scientific and Technical Information of China (English)

    梁利香; 陈琼; 陈利军

    2015-01-01

    Objective:Studies on the chemical constituents of flower volatile oil from Rabdosia amethystoides (Benth.)H. Hara. Method:The essential oil was extracted from Rabdosia amethystoides (Benth.)H.Hara.by steam distillation. Compon-ents of the essential oils were analyzed by GC-MS. Result:The main chemical components are 2-Methoxy-4-vinylphenol (33.076%), 1,3-Cyclopentadiene, 1,2,3,4-tetramethyl-5-methylene-(13.826%), Phenol, 2,3,4,6-tetramethyl-(11.426%). Con-clusion:Rabdosia amethystoides (Benth.) H. Hara.contains a lot of 2-Methoxy-4-vinylphenol, which is a common food ad-ditives. Rabdosia amethystoides (Benth.) H. Hara.can be comprehensive utilization.%目的:研究香茶菜花期挥发油的化学成分.方法:采用水蒸汽蒸馏法提取香茶菜花期的挥发油,以气相色谱—质谱联用(GC-MS)仪测定挥发油化学组分.结果:主要成分为2-甲氧基-4-乙烯基苯酚(33.076%),1,2,3,4-四甲基-5-亚甲基-1,3-环戊二烯(13.826%),2,3,4,6-四甲基苯酚(11.426%).结论:香茶菜含大量常用食品添加剂2-甲氧基-4-乙烯基苯酚,可以综合开发利用.

  15. Filaggrin gene mutations in African Americans with both ichthyosis vulgaris and atopic dermatitis.

    Science.gov (United States)

    Polcari, Ingrid; Becker, Lauren; Stein, Sarah L; Smith, Marilyn S; Paller, Amy S

    2014-01-01

    Atopic dermatitis (AD) and ichthyosis vulgaris (IV) are two common disorders of epidermal homeostasis resulting in dry skin. The profilaggrin gene, located on chromosome 1q22, encodes a keratin filament aggregating protein (filaggrin) that is essential to forming the epidermal barrier and maintaining hydration. Null mutations in filaggrin have been found to underlie IV and are common in patients with AD, but the minority of African Americans with AD or IV show these mutations in filaggrin. We have selectively studied African Americans with both AD and IV to maximize the possibility of finding filaggrin null mutations in this population. DNA was collected using buccal swabs from 18 African American children with both AD and IV and 17 African American controls without either of these diseases. Purified genomic DNA was amplified using polymerase chain reaction from three regions of the filaggrin gene, exon 3, including R501X, 2282del4, E2554X, R2447X, 1249insG, R826X, 2767insT, and E2422X. Of the African American children with both AD and IV, 22.2% were heterozygous for filaggrin null mutations. Out of the control group, one carried a null mutation and was later discovered to have a history of asthma. Null mutations found in this population included R501X (n = 1), 2282del4 (n = 2), and R826X (n = 2, including the control patient). Our data demonstrate a prevalence of filaggrin mutations in the African American population that exceeds previously published data, although the overall prevalence is still lower than in other populations. It is likely that factors other than known FLG mutations are involved in African American patients.

  16. 光量子血疗治疗神经症190例%Treatment of 190 Cases with Neurosis with Light Quantum Blood Therapy

    Institute of Scientific and Technical Information of China (English)

    王桂斌; 何伟; 王伯余

    2001-01-01

    目的 研究光量子血疗对神经症的治疗作用。方法 将380例神经症随机分为对照组和观察组,每组190例,观察组治疗方法除与对照组相同外,另加光量子血疗。结果 观察组有效率94.7%,治愈率85%,比对照组有效率82.6%、治愈率74.6%明显提高,P<0.05,尤其是癔症观察组的治愈率达100%。结论 光量子血疗治疗神经症,尤其是癔症疗效高,安全简便。%Objective To study the effects of light quantum blood therapy on neurosis. Method 380 cases with neurosis were randomly divided into two groups: the treated group and the control group, 190 cases in each group. Besides the same treatment as the control group, the treated group was treated by light quantum blood therapy. Result In the treated group, the effective rate was 94.7% and the cure rate was 85%; in the control group, the effective rate was 82.6% and the cure rate 74.6%. The effective and cure rates were obviously higher in the treated group than in the control group(P<0.05). Conclusion Light quantum blood therapy is a safe and easy method for the treatment of neurosis.

  17. Pharmaceutical care education in Kuwait: pharmacy students’ perspectives

    Directory of Open Access Journals (Sweden)

    Katoue MG

    2014-09-01

    Full Text Available Background: Pharmaceutical care is defined as the responsible provision of medication therapy to achieve definite outcomes that improve patients’ quality of life. Pharmacy education should equip students with the knowledge, skills, and attitudes they need to practise pharmaceutical care competently. Objective: To investigate pharmacy students’ attitudes towards pharmaceutical care, perceptions of their preparedness to perform pharmaceutical care competencies, opinions about the importance of the various pharmaceutical care activities, and the barriers to its implementation in Kuwait. Methods: A descriptive, cross-sectional survey of pharmacy students (n=126 was conducted at Faculty of Pharmacy, Kuwait University. Data were collected via a pre-tested self-administered questionnaire. Descriptive statistics including percentages, medians and means Likert scale rating (SD were calculated and compared using SPSS, version 19. Statistical significance was accepted at a p value of 0.05 or lower. Results: The response rate was 99.2%. Pharmacy students expressed overall positive attitudes towards pharmaceutical care. They felt prepared to implement the various aspects of pharmaceutical care, with the least preparedness in the administrative/management aspects. Perceived pharmaceutical care competencies grew as students progressed through the curriculum. The students also appreciated the importance of the various pharmaceutical care competencies. They agreed/strongly agreed that the major barriers to the integration of pharmaceutical care into practice were lack of private counseling areas or inappropriate pharmacy layout (95.2%, lack of pharmacist time (83.3%, organizational obstacles (82.6%, and pharmacists’ physical separation from patient care areas (82.6%. Conclusion: Pharmacy students’ attitudes and perceived preparedness can serve as needs assessment tools to guide curricular change and improvement. Student pharmacists at Kuwait University

  18. Accuracy of Clinical Diagnosis of Dengue Episodes in the RV144 HIV Vaccine Efficacy Trial in Thailand.

    Directory of Open Access Journals (Sweden)

    Punnee Pitisuttithum

    Full Text Available RV144 was a community-based HIV vaccine efficacy trial conducted in HIV-uninfected adults in Thailand, where dengue virus continues to cause a large number of infections every year. We attempted to document the accuracy of clinically diagnosed dengue episodes reported as serious adverse events (SAEs and adverse events (AEs and examine whether dengue serology would support the clinical diagnosis. Subjects without a clinical dengue diagnosis but with an infection or idiopathic fever were selected as a control population. Dengue serology was performed by hemagglutination inhibition on plasma samples. A total of 124 clinical dengue episodes were reported (103 SAEs and 21 AEs. Overall 82.6% of the clinically diagnosed dengue episodes were supported by a positive dengue serology: 71.4% of the AEs and 85.0% of the SAEs. Of the 100 subjects with both clinical dengue and positive serology, all presented with fever, 83% with leucopenia, 54% with thrombocytopenia, and 27% with hemorrhagic symptoms. All episodes resolved spontaneously without sequellae. Only two of 15 subjects with a negative serology presented with fever. The sensitivity and specificity of clinical dengue diagnosis were 90.9% and 74.4%, respectively, when compared to the control population, and with a positive predictive value of 82.6% and negative predictive value of 84.7% when compared to dengue serology. Clinical diagnosis of dengue is an accurate method of dengue diagnosis in adults in Thailand. Large-scale clinical trials offer the opportunity to systematically study infectious diseases such as dengue and other infections that may occur during the trial.

  19. BOVINE MASTITIS IN THE GOIÂNIA DAIRY BASIN MASTITE BOVINA NA BACIA LEITEIRA DE GOIÂNIA

    Directory of Open Access Journals (Sweden)

    Roberval Rodrigues da Costa

    2007-09-01

    Full Text Available

    This investigation was carried on in six counties of milk region around Goiânia city, state of Goiás. Seven hundred and one (701 cows in lactation were examined, from which 87 (12.41% showed c1inica1 and subclinical mastitis. The tests CMT/ Whiteside were dome on 2,717 samples of milk and from those 393 (41.46% were positive. The rnicroorganisms isolated from 701 lactocultures were: Staphilococcus aureus 172 (67.70%; Streptococcus spp. 38 (l4.96%; Corynebacterium spp. 42 (16.53%; Staphylococcu.s epidermides 38 (14.96%; Pseudomonas aeruginosa 21 (8.26%; Eschericheir coli 18 (7.08%; Serratia marceceus 12 (4.72%; Klebsiella spp 5 (1.96%; Proteus vulgaris 4 (1.57%; Candida spp 5 (1.96%; Candida spp 5 (1.96% and in 23 (9.05% there was no growing.

    Esta pesquisa foi realizada em seis municípios da bacia leiteira de Goiânia tendo sido examinadas 701 vacas lactantes, das quais 87 (12,41% apresentaram mastite clínica e subclínica. Os testes CMT/Whiteside foram realizados em 2.717 amostras de leite, sendo que 393 (14,46% resultaram positivas. Os microrganismos isolados das 701 lactoculturas foram: Staphilococcus aureus 172 (67,70%; Streptococcus spp. 38 (l4,96%; Corynebacterium spp. 42 (16 ,53%; Staphylococcu.s epidermides 38 (14 ,96%; Pseudomonas aeruginosa 21 (8,26%; Eschericheir coli 18 (7,08%; Serratia marceceus 12 (4,72%; Klebsiella spp 5 (1,96%; Proteus vulgaris 4 (1,57%; Candida spp 5 (1,96%; Candida spp 5 (1,96% e em 23 (9,05% não houve crescimento.

  20. Mandible dentition resistance of minimally invasive removal of clinical observation%下颌阻生齿的微创拔除疗效观察

    Institute of Scientific and Technical Information of China (English)

    唐沿洪

    2014-01-01

    Objective The minimally invasive extraction technology in the application of clinical wisdom teeth inextracting the impacted mandibular effect analysis. Methods In our hospital 218 cases of underjaw impacted wisdom tooth extraction in patients withapplication of minimally invasive method for extraction, analysis on the occurrence of patientsin pain, fear of the situation. Results Application of noninvasive extraction method of impacted mandibular third molar surgery in218 cases, male and female painless success rate is 96.25%on average, men and womenpatients fear rate was 8.26%.Conclusion Application effect of noninvasive technique of extraction of mandibular impacted signiifcantly,worthy of clinical application.%目的:对微创拔牙技术在临床拔除下颌低位阻生智齿中的应用效果进行探讨分析。方法对我院收治的218例下颌低位阻生智齿患者应用微创拔除的方法进行拔除,对患者术中疼痛、畏惧的发生情况进行分析。结果应用无创拔除法拔除下颌阻生智齿218例,术中男女无痛成功率平均为96.25%,男女患者术中畏惧率为8.26%。结论应用无创技术拔除下颌阻生齿疗效显著,值得临床推广应用。

  1. Prevalência de enteroparisitos na populaçao urbana de São Tomé - RN - estudo comparativo de um decênio

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Moreira Campos

    1982-12-01

    Full Text Available Objetivando a obtenção de variáveis relacionadas aos fatores sócio-econômicos e sanitários no período de dez (10 anos, os autores colheram resultados sobre a prevalência de enteroparasitas na população urbana de São Tomé, Rio Grande do Norte, cujos dados foram coletados entre 09 a 27 de julho de 1979, empregando o método da sedimentação espontânea (Hoffmann, Pons e Janer, através de exames realizados em 826 amostras de fezes, com uma positividade de565 para as diversas parasitoses intestinais e correspondendo a uma prevalência de 68,4% em função das condições ambientais que, embora melhoradas, concorrem no processo de disseminação de helmintoses e protozooses, além de outras patologias.In view of socio-economic and sanitary changes during ten (10 years, the authors gathered data on the prevaíence of enteroparasites in the urban population of São Tomé, Rio Grande do Norte. They collected from July 9 to July 27, 1979, 826 faecal samples which they examined using the spontaneous sedimentation method (Hoffmann, Pons, and Janer. 565 were positive for the various intestinal parasites, corresponding to a prevaíence of 68,4%. Although environmetal conditions have improved, they still contributed to the dissemination intestinal protozoal and helminthic infections.

  2. PENGARUH DEFATTING, FREKUENSI PENCUCIAN DAN JENIS DRYOPROTECTANT TERHADAP MUTU TEPUNG SURIMI IKAN LELE KERING BEKU [Effect of Defatting, Washing Cycle and Dryoprotectant Type on the Quality of Freeze Dried Catfish Surimi Powder

    Directory of Open Access Journals (Sweden)

    Wahyu Ramadhan*

    2014-06-01

    Full Text Available Freeze dried surimi powder is a surimi type processed by freeze drying. To utilize oversized catfish and to reduce surimi handling cost, oversized catfish has been used as raw material of surimi powder. The study aimed to determine the effect of defatting (NaHCO3 concentration and soaking duration, washingcycle,and dryoprotectant type on catfish surimi, as well as quality differences between surimi powder and wet surimi. With regard to defatting step, soaking in NaHCO3 0.75% for 10 minutes was found as the best treatment and resulting in a fat content of 1.52%. Moreover, one time of washing cycle was found as the most appropriate procedure to obtain a superior quality of surimi with whiteness value 57.21%, water holding capacity 73.28%, salts soluble protein 7.17%, pH 6.69, and gel strength 482.3 g/cm2, folding value of 4.84, and teeth cutting value of 8.26. Trehalose 6% was the most suitable dryoprotectant resulting in surimi powder with water holding capacity of 8.01 mL/g, gel strength 826.3 g/cm2, salt soluble protein 18.98%, density 4.06 mL/10 g, rehydration capacity 3.81, emulsion capacity 69.3%, emulsion stability 59.3%, foaming capacity 25.33% and foaming stability 9.40%. The microstructure profile of surimi powder added with trehalose had more compact tissues, without any damage and clots, than that treated with other dryoprotectants. However, surimi powder still had lower protein content than wet surimi, and lower physical and chemical properties, particularly in its teeth cutting and folding characteristics.

  3. Host Plant Mediated Population Variations of Cotton Whitefly Bemisia tabaci Gennadius (Aleyrodidae: Homoptera Characterized with Random DNA Markers

    Directory of Open Access Journals (Sweden)

    Yasodha Perumal

    2009-01-01

    Full Text Available Problem statement: Whitefly, Bemisia tabaci is an important sucking pest of field, horticultural and ornamental plants causing feeding injuries besides spreading disease by acting as a vector of Gemini viruses. The polyphagous nature of the pest makes it as a highly complex species. Approach: The influence of host plants utilized by the species on the population differences at molecular level was attempted using Random Amplified Polymorphic DNA (RAPD markers. Results: Ten RAPD primers out of the total seventeen primers screened produced 236 markers. The total number of bands obtained from each primer ranged from 11-35 with an average of 23.60 bands per primer. Of the pair wise combination among thirteen species, Srivilliputhur population showed the highest similarity index (0.826 while the lowest (0.111 was recorded by Namakkal population. The similarity coefficient based on the 236 RAPD markers generated ranged from 0.111-0.826. Three major clusters were formed from UPGMA dendrogram, which was constructed based on Jaccard’s similarity. PCR screening demarcated the whitefly population based on the host species. The first cluster included population collected from okra and cotton, while second cluster comprised of population from eggplant and cauliflower and the third cluster included population from eggplant. It could be deduced that population from cotton and okra had 50% similarity, while 60-70% similarity was observed for population from eggplant and cauliflower. Conclusion: Our investigation offered the lead that within a narrow geographical region there exits variation based on host plants being utilized by the whitefly population.

  4. Accuracy of Clinical Diagnosis of Dengue Episodes in the RV144 HIV Vaccine Efficacy Trial in Thailand.

    Science.gov (United States)

    Pitisuttithum, Punnee; Rerks-Ngarm, Supachai; Stablein, Donald; Dawson, Peter; Nitayaphan, Sorachai; Kaewkungwal, Jaranit; Michael, Nelson L; Kim, Jerome H; Robb, Merlin L; O'Connell, Robert J; Yoon, In-Kyu; Fernandez, Stefan; Excler, Jean-Louis

    2015-01-01

    RV144 was a community-based HIV vaccine efficacy trial conducted in HIV-uninfected adults in Thailand, where dengue virus continues to cause a large number of infections every year. We attempted to document the accuracy of clinically diagnosed dengue episodes reported as serious adverse events (SAEs) and adverse events (AEs) and examine whether dengue serology would support the clinical diagnosis. Subjects without a clinical dengue diagnosis but with an infection or idiopathic fever were selected as a control population. Dengue serology was performed by hemagglutination inhibition on plasma samples. A total of 124 clinical dengue episodes were reported (103 SAEs and 21 AEs). Overall 82.6% of the clinically diagnosed dengue episodes were supported by a positive dengue serology: 71.4% of the AEs and 85.0% of the SAEs. Of the 100 subjects with both clinical dengue and positive serology, all presented with fever, 83% with leucopenia, 54% with thrombocytopenia, and 27% with hemorrhagic symptoms. All episodes resolved spontaneously without sequellae. Only two of 15 subjects with a negative serology presented with fever. The sensitivity and specificity of clinical dengue diagnosis were 90.9% and 74.4%, respectively, when compared to the control population, and with a positive predictive value of 82.6% and negative predictive value of 84.7% when compared to dengue serology. Clinical diagnosis of dengue is an accurate method of dengue diagnosis in adults in Thailand. Large-scale clinical trials offer the opportunity to systematically study infectious diseases such as dengue and other infections that may occur during the trial.

  5. Anti-amyloidogenic activity of glutathione-covered gold nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Antosova, Andrea [Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Science, Watsonova 47, 04001 Kosice (Slovakia); Department of Biochemistry, Faculty of Science, P.J. Safarik University, Moyzesova 11, 040 01 Kosice (Slovakia); Gazova, Zuzana; Fedunova, Diana; Valusova, Eva [Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Science, Watsonova 47, 04001 Kosice (Slovakia); Bystrenova, Eva; Valle, Francesco [Institute for Nanostructured Materials ISMN-CNR, via Gobetti 101, I-40129 Bologna (Italy); Daxnerova, Zuzana [Institute of Biology and Ecology, Faculty of Science, P. J. Safarik University, Moyzesova 11, 040 01 Kosice (Slovakia); Biscarini, Fabio [Institute for Nanostructured Materials ISMN-CNR, via Gobetti 101, I-40129 Bologna (Italy); Antalik, Marian, E-mail: antalik@saske.sk [Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Science, Watsonova 47, 04001 Kosice (Slovakia); Department of Biochemistry, Faculty of Science, P.J. Safarik University, Moyzesova 11, 040 01 Kosice (Slovakia)

    2012-12-01

    This study is an investigation of the effect of biocompatible glutathione-covered gold nanoparticles (AuSG{sub 7}) with an average size of 3 nm on the amyloid fibrils of hen egg-white lysozyme. The anti-amyloid activity of AuSG{sub 7} nanoparticles on this protein was monitored with thioflavin T assay, atomic force microscopy and transmission electron microscopy. The study found that AuSG{sub 7} nanoparticles in vitro depolymerize the amyloid aggregates and inhibit lysozyme aggregate formation. The ability to inhibit amyloid formation and promote amyloid disassembly has concentration-dependent characteristics: the concentration of nanoparticles at which inhibition is half maximal (IC{sub 50}) was found to be 6.19 {mu}g/mL, and the concentration at which depolymerization is half maximal (DC{sub 50}) was found to be 8.26 {mu}g/mL. Highlights: Black-Right-Pointing-Pointer AuSG{sub 7} nanoparticles are able to interact with lysozyme amyloids at acidic pH. Black-Right-Pointing-Pointer These nanoparticles reduce the amyloid aggregates by promoting depolymerization. Black-Right-Pointing-Pointer AuSG{sub 7} nanoparticles display inhibitory action on lysozyme amyloid aggregation. Black-Right-Pointing-Pointer The half inhibition concentration (IC{sub 50}) for AuSG{sub 7} nanoparticles is 6.19 {mu}g/ml. Black-Right-Pointing-Pointer The half depolymerization nanoparticles concentration (DC{sub 50}) is 8.26 {mu}g/ml.

  6. Timpanoplastia com plugue de cartilagem na infância Plug cartilage tympanoplasty in children

    Directory of Open Access Journals (Sweden)

    José Arruda Mendes Neto

    2008-12-01

    Full Text Available O tratamento das perfurações da membrana timpânica na população pediátrica com seqüelas de Otite Média Crônica representa um desafio ao Otorrinolaringologista. OBJETIVO: Avaliar os resultados clínicos e audiométricos da técnica "inlay" com colocação de plugue de cartilagem do trago. MATERIAL E MÉTODOS: Foram analisados 23 pacientes (idade 1-15 anos submetidos à timpanoplastia com plugue. FORMA DE ESTUDO: Clínico retrospectivo. RESULTADOS: A taxa de sucesso de fechamento foi de 82,6%, com melhora dos parâmetros audiométricos em 87,5% dos pacientes. As complicações foram mínimas. CONCLUSÃO: Em face dos resultados obtidos, este método de timpanoplastia deve ser considerado uma boa opção para o tratamento das perfurações da membrana timpânica na infância.The treatment of tympanic membrane perforations in the pediatric population with sequelae of chronic otitis media represents a challenge to otolaryngologists. AIM: to assess the clinical and audiometric results of the inlay technique with a tragus cartilage plug. MATERIALS AND METHODS: we assessed 23 patients (ages between 1 and 15 years who underwent plug tympanoplasty. Study design: clinical retrospective. RESULTS: repair success rate was of 82.6%, with audiometric parameters improvement in 87.5% of the patients. Complications were minimum. CONCLUSION: considering the results attained, this method of tympanoplasty should be considered a good treatment option for tympanic membrane perforation in children.

  7. 香蕉皮果胶提取条件的优化%Optimization of Extraction Conditions of Banana Peel Pectin

    Institute of Scientific and Technical Information of China (English)

    邓红梅; 马超; 王春; 熊宏开

    2013-01-01

    以香蕉皮作为原料,对果胶提取条件进行优化,分别探讨了提取时间、提取温度、pH、料液比等因素对香蕉皮中果胶提取的影响.然后通过正交试验得出,香蕉皮中果胶提取的最佳条件为提取时间90 min、提取温度85℃、pH 1.5、料液比1:3 (m/V,g:mL),影响果胶产率的因素为pH>提取温度>提取时间>料液比.在此优化条件下,香蕉皮果胶产率可达到6.23%,提取的果胶含量为82.6%.%Using banana peel as the raw material to extract pectin,the effects of extraction time,temperature,pH and material to liquid ratio on extraction of pectin were investigated to optimize the extraction conditions.According to orthogonal experiment,the optimal extraction conditions were,extraction time,90 min,temperature,85 ℃; pH,1.5; and material to liquid ratio,1:3 (m/V,g:mL).The influencing order of these factors was pH>temperature >extraction time >material to liquid ratio.Under the optimized conditions,the pectin yield extracted from banana peel reached to 6.23%; and the content of pectin in extract was 82.6%.

  8. The effect of ketoconazole 2% solution in comparison with ketoconazole 2% shampoo on clinical signs and Malassezia yeasts in seborrhoeic dermatitis patients

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Hedayati

    2008-01-01

    Full Text Available (Received 13 Oct, 2008; Accepted 29 Dec, 2008 Abstract: Background and purpose: Seborrhoeic dermatitis (SD is a common skin disorder. Malassezia yeasts have an important role in the etiology of SD. Since anti-fungal agents, especially in azoles are effective for treating SD, in this study, the effect of ketoconazole 2% solution on clinical signs and Malassezia in SD patients were assayed. Materials and methods: 100 patients with SD were enrolled in this study. Patients were scored in regard to the severity of lesions at the initial evaluation and every 2 weeks for a 1 month period. Microscopic examination and culture of patients scale in days 0 and 28 were used for isolation and identification of Malassezia species. Patients were divided into two groups (ketoconazole 2% solution and shampoo and followed after 14 and 28 days, and then clinical response was graded. Results: 58% of patients showed lesions on their heads. In day 0, 51% of patients showed > 7 yeasts in each microscopic field. 77% of scale samples were positive to Malassezia spp. Growth and M. globosa (57.1% had the most frequency. In day 28, 89.6% and 82.6% of treated patients with solution and shampoo showed 1-3 yeast in within entire smear, respectively. 94.8% and 82.6% of scale samples were negative to Malassezia spp growth, respectively. In day 0, patients with moderate SI had the most prevalence, whereas in day 28, patients with mild SI were predominant. Statistical test showed the correlation is significance only between SI and treatment with solution. Conclusion: The results of our study showed that according to decrease of yeast load and increase of improvement of SD signs after treatment with ketoconazole 2% solution, compared with ketoconazole 2% shampoo, 2% ketoconazole solution can be considered as an appropriate agent in treatment of Sd.

  9. 护理服务质量评价量表的初步研制%Preliminary development of nursing care quality assessment scale in general hospital

    Institute of Scientific and Technical Information of China (English)

    韩俊林; 王润兰; 李建华

    2011-01-01

    Objective: To explore an assessment scale which is suitable for evaluating the present nursing care quality in general hospitals. Method: Through investigation of small group of patients and Delphi procedure, a draft scale was developed. Then 700 inpatients in two general hospitals were investigated by this final scale. Results: The answer rate was 98.71%, the Cronbach's alpha coefficient was 0.881. Confirmatory factor analysis showed five factors was fully consistent with five dimensions of questionnaire, criterion-related validity correlation was r=0.826. Conclusion: The scale has acceptable reliability and validity. It might be helpful for improving nursing care quality.%目的:探索研制适合我国现阶段综合医院的护理服务质量评价量表.方法:在住院患者护理服务需求调查的基础上,经小样本调查结合专家咨询形成正式量表,选取2所综合医院的700名住院患者进行调查.结果:调查量表回收率为98.71%.Cronbach's α系数为0.881,证实性因子分析显示,5个因素与问卷设计的5个维度完全吻合,效标关联效度检验r=0.826.结论:所研制量表具有良好的信度和效度,对护理服务质量改进具有指导作用.

  10. Estimation of Citation-Based Scholarly Activity Among Radiation Oncology Faculty at Domestic Residency-Training Institutions: 1996-2007

    International Nuclear Information System (INIS)

    Purpose: Advancement in academic radiation oncology is largely contingent on research productivity and the perceived external influence of an individual's scholarly work. The purpose of this study was to use the Hirsch index (h-index) to estimate the research productivity of current radiation oncology faculty at U.S. academic institutions between 1996 and 2007. Methods and Materials: We performed bibliometric citation database searches for available radiation oncology faculty at domestic residency-training institutions (n = 826). The outcomes analyzed included the total number of manuscripts, total number of citations, and the h-index between 1996 and 2007. Analysis of overall h-index rankings with stratification by academic ranking, junior vs. senior faculty status, and gender was performed. Results: Of the 826 radiation oncologists, the mean h-index was 8.5. Of the individuals in the top 10% by the h-index, 34% were chairpersons, 88% were senior faculty, and 13% were women. A greater h-index was associated with a higher academic ranking and senior faculty status. Recursive partitioning analysis revealed an h-index threshold of 15 (p <0.0001) as an identified breakpoint between the senior and junior faculty. Overall, women had lower h-indexes compared with men (mean, 6.4 vs. 9.4); however, when stratified by academic ranking, the gender differential all but disappeared. Conclusion: Using the h-index as a partial surrogate for research productivity, it appears that radiation oncologists in academia today comprise a prolific group, however, with a highly skewed distribution. According to the present analysis, the h-index correlated with academic ranking. Thus, it potentially has utility in the process of promotion decisions. Overall, women in radiation oncology were less academically productive than men; the possible reasons for the gender differential are discussed.

  11. 一种面向观点挖掘的多粒度话题情感联合模型%Multi-grain joint model of topic and sentiment for opinion mining

    Institute of Scientific and Technical Information of China (English)

    赵煜; 蔡皖东

    2011-01-01

    为了提高文本观点挖掘的效率,通过扩展标准话题模型,提出了一种新颖的多粒度话题情感联合模型(MG-TSJ).模型将文本话题区分为全局和局部两类,同时挖掘文本中涉及的多层次话题信息和情感倾向信息.该模型采用非监督的学习方法,解决了现有方法存在的领域依赖问题.通过在测试语料库上进行实验,该模型在文本情感倾向性分类任务中的准确率达到82.6%,具有和监督分类系统相当的性能;挖掘话题集合呈现层次化、语义相关的特点,证明了MG-TSJ模型对观点挖掘是可行的和有效的.%Based on extensions to standard topic modeling methods, a novel multi-grain joint model of topic and sentiment is proposed to improve efficiency of opinion mining.This model extracts sentiment and hierarchy topic from the text simultaneously, which distinguishes between local topics and global topics.The proposed model adopts the unsupervised learning method to address the issue of being domain dependent in existing methods.According to experiments, this model achieves an accuracy of 82.6% for sentiment classification.It has a performance comparable to that of supervised sentiment classification methods.Moreover, the acquired collection of topics is hierarchy and semantic related.It is proved that the proposed model is feasible and effective for opinion mining.

  12. Increased physical activity improves sleep and mood outcomes in inactive people with insomnia: a randomized controlled trial.

    Science.gov (United States)

    Hartescu, Iuliana; Morgan, Kevin; Stevinson, Clare D

    2015-10-01

    While high levels of activity and exercise training have been associated with improvements in sleep quality, minimum levels of activity likely to improve sleep outcomes have not been explored. A two-armed parallel randomized controlled trial (N=41; 30 females) was designed to assess whether increasing physical activity to the level recommended in public health guidelines can improve sleep quality among inactive adults meeting research diagnostic criteria for insomnia. The intervention consisted of a monitored program of ≥150 min of moderate- to vigorous-intensity physical activity per week, for 6 months. The principal end-point was the Insomnia Severity Index at 6 months post-baseline. Secondary outcomes included measures of mood, fatigue and daytime sleepiness. Activity and light exposure were monitored throughout the trial using accelerometry and actigraphy. At 6 months post-baseline, the physical activity group showed significantly reduced insomnia symptom severity (F(8,26) = 5.16, P = 0.03), with an average reduction of four points on the Insomnia Severity Index; and significantly reduced depression and anxiety scores (F(6,28) = 5.61, P = 0.02; and F(6,28) = 4.41, P = 0.05, respectively). All of the changes were independent of daily light exposure. Daytime fatigue showed no significant effect of the intervention (F(8,26) = 1.84, P = 0.18). Adherence and retention were high. Internationally recommended minimum levels of physical activity improve daytime and night-time symptoms of chronic insomnia independent of daily light exposure levels. PMID:25903450

  13. 违背善良风俗故意致人损害与纯粹经济损失保护

    Institute of Scientific and Technical Information of China (English)

    于飞

    2012-01-01

    "Intentional damage contrary to public policy" is an issue unavoidable when one investigates tort law on the base of the distinction between protection of rights and protection of interests. At the time it was established, Article 826 of the German Civil Code was not meant to connect law with extra-legal norms such as morals and customs. Later doctrinal interpretations attributed two categories of functions to Article 826, that is, the essential and the formal functions. Legal scholars became increasingly critical of the essential functions with "contrary to public policy" as the criteria for judgment, and the viewpoint that the protection of pure economic loss as the core function of Article 826 emerged in the scholarship. The essence of the intention requirement is to maintain the foreseeability for the actor in the field of pure economic loss, which lacks of typical social obviousness. The intention requirement was diluted to some extent in legal interpretation, but it should not be reduced to gross negligence. The determination of whether action is "contrary to public policy" is not beyond the law, but also not within the constitution or the general legal spirit, but within case decisions. With reference to dynamic system theory, domestic cases should be used to build our case-types of what is "intentional damage contrary to public policy". The concept of pure economic loss does not clearly delineate a category, but refers to a multitude of things, and for this there exists no general protective rule. "Intentional damage contrary to public policy" is just a minimum rule of the protection of pure economic loss. A protective system of three layers should be built up, comprising special statutes, protective statutes and "intentional damage contrary to public policy".%"背俗故意致损",是在权利和利益区分的基础上进行侵权法思考必然会遭遇的一个问题。德国民法典立法者设立第826条时,并不具有

  14. LED fluorescence microscopy for the diagnosis of pulmonary tuberculosis: a multi-country cross-sectional evaluation.

    Directory of Open Access Journals (Sweden)

    Luis Eduardo Cuevas

    2011-07-01

    Full Text Available BACKGROUND: The diagnosis of tuberculosis (TB in resource-limited settings relies on Ziehl-Neelsen (ZN smear microscopy. LED fluorescence microscopy (LED-FM has many potential advantages over ZN smear microscopy, but requires evaluation in the field. The aim of this study was to assess the sensitivity/specificity of LED-FM for the diagnosis of pulmonary TB and whether its performance varies with the timing of specimen collection. METHODS AND FINDINGS: Adults with cough ≥2 wk were enrolled consecutively in Ethiopia, Nepal, Nigeria, and Yemen. Sputum specimens were examined by ZN smear microscopy and LED-FM and compared with culture as the reference standard. Specimens were collected using a spot-morning-spot (SMS or spot-spot-morning (SSM scheme to explore whether the collection of the first two smears at the health care facility (i.e., "on the spot" the first day of consultation followed by a morning sample the next day (SSM would identify similar numbers of smear-positive patients as smears collected via the SMS scheme (i.e., one on-the-spot-smear the first day, followed by a morning specimen collected at home and a second on-the-spot sample the second day. In total, 529 (21.6% culture-positive and 1,826 (74.6% culture-negative patients were enrolled, of which 1,156 (49% submitted SSM specimens and 1,199 (51% submitted SMS specimens. Single LED-FM smears had higher sensitivity but lower specificity than single ZN smears. Using two LED-FM or two ZN smears per patient was 72.8% (385/529, 95% CI 68.8%-76.5% and 65.8% (348/529, 95% CI 61.6%-69.8% sensitive (p<0.001 and 90.9% (1,660/1,826, 95% CI 89.5%-92.2% and 98% (1,790/1,826, 95% CI 97.3%-98.6% specific (p<0.001. Using three LED-FM or three ZN smears per patient was 77% (408/529, 95% CI 73.3%-80.6% and 70.5% (373/529, 95% CI 66.4%-74.4%, p<0.001 sensitive and 88.1% (95% CI 86.5%-89.6% and 96.5% (95% CI 96.8%-98.2%, p<0.001 specific. The sensitivity/specificity of ZN smear microscopy and LED

  15. Neoproterozoic ophiolite and related high-grade rocks of the Baikal-Muya belt, Siberia: Geochronology and geodynamic implications

    Science.gov (United States)

    Kröner, A.; Fedotova, A. A.; Khain, E. V.; Razumovskiy, A. A.; Orlova, A. V.; Anosova, M. O.; Perelyaev, V. I.; Nekrasov, G. E.; Liu, D. Y.

    2015-11-01

    We report zircon for from ophiolitic and high-grade rocks of the Neoproterozoic Baikal-Muya belt of Siberia that occupies an arc-shaped area on the southeastern margin of the Siberian craton. It consists of arc-related plutonic, metavolcanic and metasedimentary rocks as well as fragmented ophiolites and high-grade metamorphic assemblages. Magmatic zircons from two plagiogranite dyke samples of the Mamakan ophiolite complex in the Sredne-Mamakan massif of the eastern Baikal-Muya belt yielded similar and concordant SHRIMP mean 206Pb/238U ages of 640.0 ± 4.1 and 650 ± 6 Ma, respectively, that reflect the time of dyke emplacement and from which we suggest an age of ca. 645 Ma as the most likely time of ophiolite formation. Enderbitic gneisses of the North Baikal area, in the western part of the Baikal-Muya belt, contain complex zircon populations that reflect variable recrystallization, Pb-loss and metamorphic overgrowth during granulite-facies metamorphism. LA-ICP-MS dating of these zircons yielded inconclusive results that led us to undertake a detailed study of cathodoluminescence images combined with U-Pb SHRIMP dating. Well-preserved magmatic domains in zircons from enderbite sample 2821 yielded concordant results with a mean 206Pb/238U age of 640 ± 5 Ma, slightly higher but broadly comparable with the data obtained by LA-ICP-MS. The zircon populations of two more enderbitic gneiss samples are more complex, and their LA-ICP-MS data constitute broad swaths along concordia between ca. 840 and 600 Ma, reflecting two end-member isotopic components, namely an igneous crystallization event at ca. 800 Ma and a Pb-loss and recrystallization event at ca. 600 Ma. SHRIMP analyses of magmatic zircon domains of these samples yielded concordant data with identical mean 206Pb/238U ages of 826 ± 7.5 Ma and 826 ± 8 Ma, respectively, whereas low-U metamorphic rims crystallized at 640 ± 7 Ma. Newly crystallized ball-round metamorphic zircons in one sample produced a mean 206Pb

  16. The Bristol Stool Form Scale: its translation to Portuguese, cultural adaptation and validation Traducción, adaptación cultural y validación de la "Bristol Stool Form Scale" Tradução, adaptação cultural e validação da Bristol Stool Form Scale para a população brasileira

    Directory of Open Access Journals (Sweden)

    Anna Paula Martinez

    2012-06-01

    Full Text Available The Bristol Stool Form Scale is used for describing feces. The objective of this research was its translation, cultural adaptation and validation for Brazil. The methodology was translation, back-translation and discussion. Validation involved 85 nurses, 80 doctors, and 80 patients, who correlated images of seven types of feces with the descriptions. Results: there was a difference in sex distribution, with males predominating among the doctors and females among nurses and patients. In relation to concordance between definitions and pictures, the highest percentage was in type 5 in all three groups and the lowest was in types 6 and 7 for the doctors, in type 3 for the nurses, and type 6 for the patients. The general Kappa index was 0.826. Conclusion: the scale demonstrated high reliability for all the groups studied.La "Bristol Stool Form Scale" es usada para describir las heces. Objetivo: traducción, adaptación cultural y la validación para ser utilizada en Brasil. Metodología: Fue realizada la traducción, la traducción inversa y la discusión final. Para validar, se incluyeron 85 enfermeros y 80 médicos y pacientes que correlacionaron diseños de siete tipos de heces con descripciones. Resultados - Hubo diferencia en cuanto a la distribución del sexo con predominio masculino entre los médicos y femenino para los enfermeros y pacientes. Con respecto a la concordancia entre los conceptos y las imágenes, la mayor concordancia fue del tipo 5 en cuanto que el de menor correspondencia para los médicos fueron los tipos 6 y 7, para los enfermeros el 3 y el 6 para los pacientes. El índice de Kappa general fue de 0,826. Conclusión: Los valores obtenidos demuestran la alta confiabilidad de este cuestionario con respecto a los grupos estudiados.A Escala de Bristol para Consistência de Fezes é usada na descrição de fezes. O objetivo deste estudo foi realizar a tradução, adaptação cultural e validação para o Brasil, dessa escala. Como

  17. Mechanical properties non-destructive testing of wooden components of Korean pine based on stress wave and micro-drilling resistance%基于应力波和微钻阻力的红松类木构件力学性能的无损检测

    Institute of Scientific and Technical Information of China (English)

    朱磊; 张厚江; 孙燕良; 王喜平; 闫海成

    2013-01-01

    为了现场快速无损检测评估红松类古建筑木构件材料的主要力学性能,以红松为研究对象,对其进行应力波速度、微钻阻力值、含水率、弹性模量、弯曲强度的测定,探索红松材料力学性能无损检测方法,建立红松木构件材料力学性能计算模型.与单一无损检测方法(应力波检测方法、微钻阻力检测方法)的检测结果对比,采用应力波与微钻阻力检测相结合的方法(即利用应力波-阻力模量)推算被测材料的主要力学性能,准确度更高,红松波阻模量与材料抗弯弹性模量、抗弯强度的相关系数分别为0.826、0.724.%Korean pine timber samples were elected as experimental materials. Laboratory experiments were conducted to obtain stress wave speed, micro-drilling resistance, moisture content, as well as bending stiffness and strength for, exploring non-destructive testing methods of detecting the main mechanical properties. The pine performance computing model for the future on-site rapid test and evaluation were established at the mean time. After comparing with any single non-destructive testing method (stress wave detection, micro-drilling resistance tests), the modulus of stress-resisto-graph testing method had higher accuracy. Analysis indicated the modulus of stress-resistograph in the linear regression relationships with the modulus of elasticity (MOE) , modulus of rupture ( MOR) , and the coefficient of determination were 0.826, 0.724, respectively.

  18. 地震早期伤病特点及应急医疗队适宜技术筛选研究%Invaliding spectrum analysis and screening research of appropriate technology of medical corps in the early period after earthquakes

    Institute of Scientific and Technical Information of China (English)

    刘蓉蓉; 秦银河; 周林

    2012-01-01

    Objective To analyze the characlerislic of invaliding speclrum and Lo determine the appropriate Lechnology of medical corps in the early period after earthquakes with scientific melhods. Methods The Lrauma database syslem V3. 0 was used Lo indenlify abbreviated injury score ( AIS) of 826 early wounded cases and Lo analyze ihe characlerislics of them. The assessment index syslem of the appropriale technology including 8 Ⅱ - grade indexes belonging lo 3 Ⅰ - grade index was constructed first. Then, the weights of these indexes were determined by analytic hierarchy process. A total of 33 emergency technologies were scored by 15 specialists, and the mathematical mean acted as the score of a certain index. The final score was computed by weight sum model, then the appropriale technologies were chosen according lo the screening standards. Results A total of 25 appropriate lechnology were determined, including incision of tracheal, packing, slop bleeding, ect. Conclusion The choice of the appropriate lechnology benefits lo deploy the rescue power reasonably in the early period after earthquakes, and decide the remedy scope scientifically, and improve the efficiency and effect of remedy.%目的 在分析地震早期(震后3天)伤病特点的基础上选择应急医疗队的适宜技术.方法 应用对我院收治的826例伤员进行简明创伤量表评分(abbreviated injury score,AIS),分析地震早期伤员的伤病特点.首先构建适宜技术评价指标体系,包括3个Ⅰ级指标及8个Ⅱ级指标.然后采用层次分析法确定各指标权重,由15位专家对33种应急医疗技术进行评分,取算术平均值作为某项指标的得分.并采用加权求和模型计算该项技术的最终得分,再按照筛选标准进行选择.结果 确定了包括气管切开、包扎止血等25种适宜技术.结论 选择适宜的救治技术有利于在地震早期合理配置医疗救援力量,科学确定应急医疗队救治范围,提高救治效率和效果.

  19. 氧化淀粉的机械活化木薯淀粉干法制备%Dry Preparation of Oxidized Starch by Mechanical Activation of Cassava Strarch

    Institute of Scientific and Technical Information of China (English)

    韦艳枝; 黄祖强; 胡华宇; 余青云; 莫智宇; 张燕娟

    2012-01-01

    Oxidized starch was prepared by dry process during with activation and reaction happened synchronously using self-designed stirred mill as reactor, cassava starch as raw material and peracetic acid as oxidant. The effects of activation time, activation temperature, dosages of oxidant and catalyst on oxidation of starch were investigated by using carboxyl content of oxidized starch as evaluating index. In addition, the functional groups of reaction product were characterized by FI-IR. The results indicated that mechanical activation considerably enhanced the oxidation reaction of cassava starch. Under the conditions of activation time 60min, activation temperature 50℃, dosage of oxidant 3:840%, dosage of catalyst 0.03%, the carboxyl content of oxidized starch was 1.826%. However, under the same preparation conditions without mechanical activation, the carboxyl content of oxidized starch was only 0.039%. The FI-IR spectra showed obvious carbonyl absorption peaks of oxidation starch.%以过氧乙酸为氧化剂、自制的高能效搅拌磨为反应器,采用边活化边反应的方法对木薯淀粉进行干法氧化以制备氧化淀粉.以羧基含量为评价指标,分别考察反应时间、反应温度、氧化剂用量、催化剂用量等因素对淀粉氧化反应的影响,并利用红外光谱仪对产物进行官能团分析.结果表明,机械活化对木薯淀粉过氧乙酸氧化反应有显著强化作用.在反应时间为60 min、反应温度为50℃、氧化剂用量为3.840%、催化剂用量为0.03%时所制得的氧化淀粉羧基含量为1.826%,而在相同条件下,由原木薯淀粉制得的氧化淀粉羧基含量仅为0.039%.红外光谱显示,氧化淀粉出现明显的羰基吸收峰.

  20. The effect observation of arteriovenous pump in treating postoperative breast cancer patients with limb lymphedema%动静脉泵应用在乳腺癌术后患肢淋巴水肿的效果观察

    Institute of Scientific and Technical Information of China (English)

    邓芳芳

    2011-01-01

    Objective To evaluate the effect of arteriovenous pump in treating postoperative breast cancer patients with limb lymphedema Methods The arteriovenous pump was applied to 36 postoperative breast cancer patients who suffered from limb lymphedema. Intervention was given twice a day with 40 minutes each time. At the same time observation was done in terms of limb skin integrity, skin color, temperature, the opisthenar arteriopalmus, and the feeling pressure of the palm. The values were compared before and after the treatment. Results After 4 - week long treatment, wrist circumference measurements decreased (8.26 ±3.58) mm compared with the value before the treatment, elbow (9.67 + 3.54) mm, and shoulder (10.58 + 5.52) mm. Conclusion The application of arteriovenous pump is effective in treating postoperative breast cancer patients with limb lymphedema and is worth popularizing.%目的 评价动静脉足泵在治疗乳腺癌术后患肢淋巴水肿的效果.方法 对36例乳腺癌术后合并患肢淋巴水肿的患者应用动静脉泵治疗仪治疗,40 min/次,2次/d进行干预.同时观察患肢皮肤的完整性、皮肤颜色、温度、手背动脉搏动、手心压力感觉等,并在治疗前后进行比较.结果 治疗4周后患者腕部周长测量值较治疗前减少(8.26±3.58)mm,肘部减少(9.67±3.54)mm,肩部减少(10.58±5.52)mm.结论 动静脉泵治疗仪治疗乳腺癌术后患肢淋巴水肿有较好的疗效,值得推广使用.

  1. 聚L-精氨酸/石墨烯修饰电极对日落黄的测定%The determination of sunset yellow by poly-L-arginine-graphene modified electrode

    Institute of Scientific and Technical Information of China (English)

    胡晴晴; 朱庆仁; 孙登明

    2015-01-01

    The poly-L-arginine-graphene modified electrode (PLA-ERGO/GCE) was fabricated by cyclic voltam-metric method. Due to the fast electron transfer rate and better catalytic ability on PLA-ERGO/GCE, the electro-chemical behaviors of sunset yellow was studied by cyclic voltammetric method (CV) and differential pulse voltam-metry (DPV). The redox process of sunset yellow was controlled by adsorption. Under optimal experiment conditions, the oxidation peak potential of sunset yellow was at 0.826 V. The calibration curves for sunset yellow was obtained in the range of 7.50×10-7~1.00×10-3 mol/L by DPV. The detection limit was 1.0×10-7 mol/L. This method had been suc-cessfully applied to the determination of sunset yellow in the sample with satisfactory results.%采用循环伏安法制备了聚L-精氨酸/石墨烯修饰电极(PLA-ERGO/GCE),该电极对日落黄(SY)有较快的电子传递速度和较好的催化性能。利用循环伏安法(CV)和差分脉冲伏安法(DPV)探究了SY在该电极上的电化学行为,SY在电极表面的氧化还原过程受吸附控制。在最佳实验条件下,SY在0.826 V处产生一个氧化峰。采用DPV法测定SY的线性范围为7.50×10-7~1.00×10-3 mol/L,检出限为1.0×10-7 mol/L。方法用于样品中日落黄的测定,结果满意。

  2. Analysis of BRAF and NRAS Mutation Status in Advanced Melanoma Patients Treated with Anti-CTLA-4 Antibodies: Association with Overall Survival?

    Directory of Open Access Journals (Sweden)

    Joanna Mangana

    Full Text Available Ipilimumab and tremelimumab are human monoclonal antibodies (Abs against cytotoxic T-lymphocyte antigen-4 (CTLA-4. Ipilimumab was the first agent to show a statistically significant benefit in overall survival in advanced melanoma patients. Currently, there is no proven association between the BRAFV600 mutation and the disease control rate in response to ipilimumab. This analysis was carried out to assess if BRAFV600 and NRAS mutation status affects the clinical outcome of anti-CTLA-4-treated melanoma patients. This is a retrospective multi-center analysis of 101 patients, with confirmed BRAF and NRAS mutation status, treated with anti-CTLA-4 antibodies from December 2006 until August 2012. The median overall survival, defined from the treatment start date with the anti-CTLA-4. Abs-treatment to death or till last follow up, of BRAFV600 or NRAS mutant patients (n = 62 was 10.12 months (95% CI 6.78-13.2 compared to 8.26 months (95% CI 6.02-19.9 in BRAFV600/NRASwt subpopulation (n = 39 (p = 0.67. The median OS of NRAS mutated patients (n = 24 was 12.1 months and although was prolonged compared to the median OS of BRAF mutated patients (n = 38, mOS = 8.03 months or BRAFV600/NRASwt patients (n = 39, mOS = 8.26 months the difference didn't reach statistical significance (p = 0.56. 69 patients were able to complete 4 cycles of anti-CTLA-4 treatment. Of the 24 patients treated with selected BRAF- or MEK-inhibitors, 16 patients received anti-CTLA 4 Abs following either a BRAF or MEK inhibitor with only 8 of them being able to finish 4 cycles of treatment. Based on our results, there is no difference in the median OS in patients treated with anti-CTLA-4 Abs implying that the BRAF/NRAS mutation status alone is not sufficient to predict the outcome of patients treated with anti-CTLA-4 Abs.

  3. Analysis of BRAF and NRAS Mutation Status in Advanced Melanoma Patients Treated with Anti-CTLA-4 Antibodies: Association with Overall Survival?

    Science.gov (United States)

    Mangana, Joanna; Cheng, Phil F; Schindler, Katja; Weide, Benjamin; Held, Ulrike; Frauchiger, Anna L; Romano, Emanuella; Kähler, Katharina C; Rozati, Sima; Rechsteiner, Markus; Moch, Holger; Michielin, Olivier; Garbe, Claus; Hauschild, Axel; Hoeller, Christoph; Dummer, Reinhard; Goldinger, Simone M

    2015-01-01

    Ipilimumab and tremelimumab are human monoclonal antibodies (Abs) against cytotoxic T-lymphocyte antigen-4 (CTLA-4). Ipilimumab was the first agent to show a statistically significant benefit in overall survival in advanced melanoma patients. Currently, there is no proven association between the BRAFV600 mutation and the disease control rate in response to ipilimumab. This analysis was carried out to assess if BRAFV600 and NRAS mutation status affects the clinical outcome of anti-CTLA-4-treated melanoma patients. This is a retrospective multi-center analysis of 101 patients, with confirmed BRAF and NRAS mutation status, treated with anti-CTLA-4 antibodies from December 2006 until August 2012. The median overall survival, defined from the treatment start date with the anti-CTLA-4. Abs-treatment to death or till last follow up, of BRAFV600 or NRAS mutant patients (n = 62) was 10.12 months (95% CI 6.78-13.2) compared to 8.26 months (95% CI 6.02-19.9) in BRAFV600/NRASwt subpopulation (n = 39) (p = 0.67). The median OS of NRAS mutated patients (n = 24) was 12.1 months and although was prolonged compared to the median OS of BRAF mutated patients (n = 38, mOS = 8.03 months) or BRAFV600/NRASwt patients (n = 39, mOS = 8.26 months) the difference didn't reach statistical significance (p = 0.56). 69 patients were able to complete 4 cycles of anti-CTLA-4 treatment. Of the 24 patients treated with selected BRAF- or MEK-inhibitors, 16 patients received anti-CTLA 4 Abs following either a BRAF or MEK inhibitor with only 8 of them being able to finish 4 cycles of treatment. Based on our results, there is no difference in the median OS in patients treated with anti-CTLA-4 Abs implying that the BRAF/NRAS mutation status alone is not sufficient to predict the outcome of patients treated with anti-CTLA-4 Abs.

  4. Three-dimensional Conformal Radiotherapy with Temozolomide in the Treatment of Postoperative Malignant Gliomas%恶性胶质瘤术后采用三维适形放疗联合替莫唑胺化疗临床观察

    Institute of Scientific and Technical Information of China (English)

    牛华涛; 梁振; 王佳; 袁红平; 罗林; 左频

    2011-01-01

    目的 观察术后三维适形放疗加替莫唑胺同步和辅助化疗治疗恶性脑胶质瘤的近期疗效和不良反应.方法 收集2008年1月至2010年6月收治的23例恶性脑胶质瘤切除术后患者,行三维适形放疗2.0 Gy/(次·d),5 d/周,总剂量60~ 70 Gv,替莫唑胺同步化疗6周+辅助化疗5疗程.结果 23例患者有效率为82.6%,6个月无疾病进展生存率为73.9% (17/23),1a无疾病进展生存率52.2% (12/23),1a生存率为69.6%(15/23);患者对治疗的耐受性良好,常见的不良反应为恶心、呕吐.结论 恶性脑胶质瘤术后三维适形放疗联合替莫唑胺化疗近期疗效较好,且患者对治疗的耐受性较好,是目前较好的治疗方案.%Objective To observe the clinical efficacy and side effects of three-dimensional conformal radiotherapy concomitant with temozolomide in the treatment of postoperative malignant gliomas in Chinese patients. Methods Twenty-three malignant glioma patients previously treated with resection of the tumor received three-dimensional conformal radiotherapy with concomitant and adjuvant temozolomide chemothreapy. Results The overall response rate was 82.6%. The progression-free survival was 73.9% (17/23) at 6 months and 52.2% (12/23) at 1 year respectively. The one- year survival rate was 69.6% (15/23 ). All patients could well tolerate this treatment scheme. The main side effects were nausea and vomit. Conclusions Three dimensional conformal radiotherapy concomitant with temozolomide in the treatment of postoperative malignant gliomas demonstrates good tolerance and short-term efficacy.

  5. Biodiversity and community composition of sediment macrofauna associated with deep-sea Lophelia pertusa habitats in the Gulf of Mexico

    Science.gov (United States)

    Demopoulos, Amanda W.J.; Bourque, Jill R.; Frometa, Janessy

    2014-01-01

    Scleractinian corals create three-dimensional reefs that provide sheltered refuges, facilitate sediment accumulation, and enhance colonization of encrusting fauna. While heterogeneous coral habitats can harbor high levels of biodiversity, their effect on the community composition within nearby sediments remains unclear, particularly in the deep sea. Sediment macrofauna from deep-sea coral habitats (Lophelia pertusa) and non-coral, background sediments were examined at three sites in the northern Gulf of Mexico (VK826, VK906, MC751, 350–500 m depth) to determine whether macrofaunal abundance, diversity, and community composition near corals differed from background soft-sediments. Macrofaunal densities ranged from 26 to 125 individuals 32 cm−2 and were significantly greater near coral versus background sediments only at VK826. Of the 86 benthic invertebrate taxa identified, 16 were exclusive to near-coral habitats, while 14 were found only in background sediments. Diversity (Fisher’s α) and evenness were significantly higher within near-coral sediments only at MC751 while taxon richness was similar among all habitats. Community composition was significantly different both between near-coral and background sediments and among the three primary sites. Polychaetes numerically dominated all samples, accounting for up to 70% of the total individuals near coral, whereas peracarid crustaceans were proportionally more abundant in background sediments (18%) than in those near coral (10%). The reef effect differed among sites, with community patterns potentially influenced by the size of reef habitat. Taxon turnover occurred with distance from the reef, suggesting that reef extent may represent an important factor in structuring sediment communities near L. pertusa. Polychaete communities in both habitats differed from other Gulf of Mexico (GOM) soft sediments based on data from previous studies, and we hypothesize that local environmental conditions found near L

  6. 三门峡市学龄前儿童身高体重调查%Investigation on Growth and Development of Preschool Children in Sanmenxia

    Institute of Scientific and Technical Information of China (English)

    郭丽

    2012-01-01

    目的 了解三门峡市幼儿园儿童生长发育状况,提出改进意见. 方法 采用全国统一的测量方法,测量2所幼儿园826名儿童(男410名,女416名)的身高和体重.使用SPSS16.0进行分析,运用2009年我国7岁以下儿童生长发育参照标准计算Z评分,与2002年中国居民营养与健康调查结果比较. 结果 营养不良率、生长迟缓率、消瘦率及超重率按照国家标准计算所得结果均低于全国城市平均水平,肥胖发生率与2002年全国水平相当. 结论 本次调查儿童体格发育总体上优于我国2009年标准,生长发育状况良好.%Objective To investigate the physical development of children in Sanmenxia, and to put forward some suggestions for the improvement. Methods The body weight and height of 826 preschool children (410 boys and 416 girls) aged 3 to 7 years in the 2 kindergartens of Sanmenxia City were measured by the national unified measurement method. The China Child Growth Standard was used to compute the Z- scores with SPSS16.0 software, and then the Z-scores were compared with the results of 2002 national nutrition survey. Results The rates of malnutrition, stunting, underweight and overweight which counted by the national standards were all lower than the average levels of the whole country, but the rate of obesity was similar to that of the whole country. Conclusions In general, the growth and development of the surveyed children are better than 2009 national growth standards, and the growth and development status of these children are good.

  7. 云南金沙江干热河谷地区麻疯树生物量的变化%Biomass Change of Jatropha curcs in Dry-hot Valley Areas of Jinsha River in Yunnan

    Institute of Scientific and Technical Information of China (English)

    陈喜英; 谷勇; 殷瑶; 吴昊; 齐泮仑

    2011-01-01

    为实现麻疯树资源的可持续利用和科学管理,并为估算麻疯树生态系统的碳汇提供依据,于2009年7月对云南省金沙江干热河谷地区的元谋、永胜、华坪3县半野生的麻疯树进行了生物量调查.结果表明:6~15年生麻疯树生理活动达到高峰期,生物量迅速增加;地上部分生物量与主干、叶、枝条的生物量符合线性模型,各构件生物量与树龄的关系符合生长曲线模型,其中地上部分生物量与树龄的关系符合3次曲线方程,地下部分生物量与树龄的关系符合逻辑曲线方程;地上部分各构件生物量比率随树龄的变化呈不同的变化规律;根系中主根生物量最大,占全根系的58.7%~82.6%,须根最小,仅占0.7%~6.2%.%The biomass of semi-wild Jatropha curcas in Yuanmou, Yongsheng and Huaping counties (dry-hot valley areas of Jinsha River in Yunnan) was surveyed in 2009 to realize sustainable utilization and scientific management of Jatropha curcas resource and provide the basis for estimating carbon sink ofJatropha curcas ecological system. The results showed that the physiological activity of Jatropha curcas with 6~15 years old reached the peak, its biomass increased rapidly, there was a linear model in biomass between the aerial part and trunk, leaf, branch, the relationship between biomass of different parts and tree age fitted the growth curve model, the relationship between aerial part biomass and tree age fitted the cubic curve equation, the relationship between biomass of underground part and tree age fitted the logic curve equation, the biomass ratio between different aerial parts showed different variation regulation with change of tree age, the biomass of main root was maximum (58.7~82.6%) and the biomass of fibrous root was minimum (0.7%~6.2%).

  8. Herdabilidades e correlações genéticas de características de machos e fêmeas, em um rebanho bovino da raça Canchim

    Directory of Open Access Journals (Sweden)

    Gianlorenço Viviane Karina

    2003-01-01

    Full Text Available O objetivo deste trabalho foi estimar as herdabilidades e as correlações genéticas do peso (P12 e do perímetro escrotal (PE12 de machos aos 12 meses de idade, da idade de descarte (TPR, tempo de permanência no rebanho de fêmeas e do número (ND10 e de quilogramas (QD10 de bezerros desmamados pelas fêmeas em até dez anos de idade, em um rebanho da raça Canchim. Foram utilizadas 1.370, 826, 826, 2.726 e 1.051 observações de TPR, ND10, QD10, P12 e PE12, respectivamente. As estimativas dos componentes de (covariância foram obtidas pelo método bayesiano, para todas as características em questão, P12, PE12, TPR, ND10 e QD10. O modelo estatístico incluiu, além dos efeitos aleatórios genético aditivo direto e residual, os efeitos fixos de ano de nascimento do animal para todas as características, de mês de nascimento para P12 e PE12 e da covariável idade do animal para PE12. As estimativas de herdabilidade, obtidas pelas análises unicaráter foram iguais a 0,38; 0,52; 0,24; 0,33 e 0,34 para P12, PE12, TPR, ND10 e QD10, respectivamente, indicando que as características possuem variação genética aditiva suficiente para apresentar boa resposta à seleção. As correlações genéticas de TPR (0,33 e 0,33, respectivamente, ND10 (0,38 e 0,30, respectivamente e QD10 (0,61 e 0,41, respectivamente com P12 e PE12, obtidas pelas análises bicaráter, sugerem que a seleção com base no peso e no perímetro escrotal dos machos não deve resultar em decréscimo no tempo de permanência das fêmeas no rebanho e no número e quilogramas de bezerros produzidos pelas fêmeas em até dez anos de idade.

  9. 响应面优化草鱼发酵工艺条件%Optimization on Fermenting Conditions of Grass Crap with Response Surface Method

    Institute of Scientific and Technical Information of China (English)

    周吉; 裘迪红

    2014-01-01

    In order to effectively prolong the preserving period of the processed grass crap and improve its flavor and commercial value, the experiment conducted in this research tries to ferment grass crap by applying Lactobacillus plantarum as the strains. Taking the total acid content as the main variable, and based on a single-factor experiment, a four-factor and five-level test in this study is designed using the Design-Expert 7 statistical analysis software, and the optimal condition of the fermentation of grass crap is obtained through a quadratic regression model which contains the variables of the amount of salt, fermentation temperature, fermentation time and inoculation amount. Based on the test result, the optimal fermentation condition is that the amount of salt, the fermentation temperature, the fermentation time and the inoculation amount should be configured with ratio of 5.5%, 29.5℃, 25.9 h and 7.4% respectively, and only on this condition can the total acid content and the score of sensory assessment reach 15.61‰ and 82.6, respectively.%利用一株植物乳杆菌为发酵菌种,对草鱼进行发酵.以总酸含量为主要指标,在单因素试验的基础上,运用Design-Expert 7 Trial统计分析软件,设计4因素5水平试验,建立加盐量、发酵温度、发酵时间和接种量的二次回归模型,得到草鱼发酵的最优条件.研究结果表明:最优的发酵工艺条件为加盐量5.5%,发酵温度29.5℃,发酵时间25.9 h,接种量7.4%,在此条件下发酵草鱼的总酸含量可达15.61‰,且感官评分值达到82.6分.

  10. 乌鲁木齐市2006~2009年预防性体检复查两对半结果分析%Analysis on two semi-hepatitis b repetitive testing for preventive health check-up in urumqi from 2006 to 2009

    Institute of Scientific and Technical Information of China (English)

    木妮热.依布拉音; 杨艳梅; 曹琦; 尚月梅

    2012-01-01

    目的 了解从事食品、餐饮及公共场所从业人员中乙肝病毒(HVB)感染标志物的分布情况,为预防控制乙肝提供依据.方法 采用酶联免疫法对272 764名体检人员进行HBsAg筛查,对阳性者做两对半检测并对结果进行分析.结果 HBsAg阳性率为1.06%,共有14种模式,HBsAg阳性者为感染组,占91.74%,HBsAg阴性者则为恢复组,占8.26%.小三阳、大三阳和隐性大三阳者分别为51.81%、17.92%和17.81%.结论 在乌鲁木齐市HBsAg的阳性率低于全国平均水平,但员工中潜在着一定的乙肝病毒传播,仍要注意加强对乙肝的预防及治疗.%OBJECTIVE To understand the message of the signs distribution of foodstuff, dining-employee and public workers infection of two semi-hepatitis B, and prevent and control the hepatitis B. provide the basis. METHODS The enzyme-linked immunosorbent assay test was used to detect the serological markers of HBV among 272 764 cases. The two Semi-hepatitis B Testing was used to test the positive of HBV markers. RESULTS The positive rate of HBeAg was 1.06% , and there were 14 modes in 272 764 cases. Among the infection group, the positive rate of HBeAg was 91.74%. The negative rate of HBeAg was 8.26% in the resume group. The most prevalent combination of the HBV markers included three kinds of patterns: positive of HBsAg, HBeAband HBcAb, the positive of HBsAg, HBeAg and HBcAb, and the positive of HBsAg and HBcAb, which accounted for 1.81%, 17.92% and 17.81%, respectively. CONCLUSION Positive of Hepatitis B in Urumqi was lower than the national level. There were still spread of type B hepatitis in employees, and we should pay attention to the prevention and treatment of hepatitis B.

  11. Synthesis of Multi-Walled Carbon Nanotube/Polymer Composite Latex%多壁碳纳米管/聚合物复合乳液的合成

    Institute of Scientific and Technical Information of China (English)

    许民; 周春华; 丰瑛

    2012-01-01

    Multi-walled carbon nanotube/poly(styrene-butyl acrylate-acrylic acid) ( MWCNTs/P (St-BA-AA)) composite latex was synthesized using in-situ emulsion polymerization,and the best conditions of in-situ emulsion polymerization were found out with orthogonal texts. According to the analytic detection of Fourier transform infrared spectra, Raman spectra and thermal gravimetric analysis (TGA) ,it is shown that the surfaces of MWCNTs are grafted assuredly with P( St-BA-AA) chains by covalent bonds. SEM photos show that MWCNTs are coated with a layer of polymer and dispersed well in the emulsion of P( St-BA-AA). Dynamically mechanical analyzer (DMA) and mechanical property tests show that,compared with pure polymer films,the tanδ,the tensile strength, the elongation at break and the elastic modulus of the nanocomposite with 1.0 w% MWCNTs are increased by 51.7% ,52. 8% ,66.7% ,and 82.6% .respectively, and the tanδ still exceeds 0.5 in the high-temperature range.%采用原位乳液聚合法合成多壁碳纳米管/聚(苯乙烯-丙烯酸丁醋-丙烯酸)( MWCNTs/P( St - BA - AA))复合乳液,通过正交实验确定原位乳液聚合的最佳条件.经红外光谱、拉曼光谱和热重分析(TGA)测试,结果表明:通过共价键在MWCNTs表面成功引入P(St - BA - AA)共聚物长链.扫描电镜(SEM)观察显示MWCNTs的表面包覆有一层聚合物,并在复合乳液中均匀分散.动态力学分析仪(DMA)和力学性能测试结果表明当MWCNTs的加入质量分数为1.0%时,复合薄膜与纯聚合物薄膜相比,内耗、拉伸强度、断裂伸长率及弹性模量分别提高了51.7%、52.8%、66.7%及82.6%,在高温区tanδ仍大于0.5.

  12. 癌症患者感知护理服务质量量表的汉化及信效度研究%Reliability and validity of Chinese version of the Oncology Patients' Perceptions of the Quality of Nursing Care Scale

    Institute of Scientific and Technical Information of China (English)

    刘淑霞; 范福玲

    2015-01-01

    目的 对癌症患者感知护理服务质量量表(OPPQNCS)进行汉化,并评价中文版OPPQNCS的信效度.方法 采用Brislin翻译模式对英文版OPPQNCS进行汉化,并将中文版OPPQNCS应用于320例癌症患者中,对测定结果进行信效度分析.结果 中文版OPPQNCS的Cronbachα系数为0.804~0.964,均>0.70;量表的重测信度为0.826.量表内容效度指数(CVI)为0.845~1.000,所有指标的平均CVI为0.925;因子分析共提取4个公因子,累积贡献率为78.548%;且各条目的因子载荷均>0.4.结论 中文版OPPQNCS具有较好的信效度,可以用其评价癌症患者的感知护理服务质量.%Objective To translate the English version of the Oncology Patients' Perceptions of the Quality of Nursing Care Scale (OPPQNCS) into Chinese and to test the reliability and validity of the Chinese version of OPPQNCS in oncology patients.Methods The English version of OPPQNCS was translated by Brislin translation mode.Totally 320 oncology patients were recruited and were investigated by the Chinese version of OPPQNCS.Results The internal consistency coefficient of the Chinese version of OPPQNCS was more than 0.70,ranged from 0.804 to 0.964;the test-retest was 0.826.The content validity index(CVI) was 0.845-1.000,the average CVI was 0.925.Factor analysis got four factors,which explained 78.548% of the total variance.And every objective factor loading were greater than 0.4.Conclusions The Chinese version of OPPQNCS has been proved to be reliable and valid.It can be used as a valid tool for the oncology patients to measure their perceptions of the quality of nursing care they got.

  13. Physico-chemical characteristics and nutraceutical distribution of crude palm oil and its fractions

    Directory of Open Access Journals (Sweden)

    Prasanth Kumar, P. K.

    2014-06-01

    Full Text Available Crude palm oil (CRPO was dry fractionated at 25 °C to get crude palm olein (CRPOL, 77% and crude palm stearin (CRPS, 23%. Low and high melting crude palm stearin (LMCRPS 14.3% and HMCRPS 8.7% were separated by further fractionation of CRPS with acetone. The physico-chemical parameters and nutraceutical distribution showed variation in different fractions. The CRPO contained 514.7 mg·Kg−1 of β-carotene and 82.6%, 16.1%, 12.5% and 3.1% of it was distributed in CRPOL, CRPS, LMCRPS and HMCRPS respectively. The distribution of phytosterols in fraction was 1870.2, 1996.8, 1190.9, 1290.4 and 115.4 mg·Kg−1 for CRPO, CRPOL, CRPS, LMCRPS and HMCRPS respectively. Total tocopherol composition was 535.5, 587.1, 308.0, 305.6 and 36.2 mg·Kg−1 for CRPO, CRPOL, CRPS, LMCRPS and HMCRPS respectively. The results show that the fractionation of CRPO may be helpful in the preparation of nutraceutical-rich fractions.Aceite de palma crudo (CRPO fue fraccionado en seco a 25 °C para obtener oleína de palma cruda (CRPOL, 77% y estearinas de palma cruda (CRPS, el 23%. Estearinas con bajo y alto punto de fusión (LMCRPS 14,3% y HMCRPS 8,7% se separan por fraccionamiento adicional de CRPS con acetona. Los parámetros físico- químicos y la distribución de nutracéuticos muestra diferencias entre las fracciones. El CRPO contenía 514,7 mg·Kg−1 de β-caroteno y el 82,6%, 16,1%, 12,5% y 3,1% de este se distribuye en CRPOL, CRPS, LMCRPS y HMCRPS respectivamente. Los fitosteroles en las fracciones fue de: 1870,2, 1996,8, 1190.9, 1290,4 y 115,4 mg·Kg−1 para CRPO, CRPOL, CRPS, LMCRPS y HMCRPS respectivamente. La composición total de tocoferol fue 535,5, 587,1 308,0, 305,6 y 36,2 mg·Kg−1, para CRPO, CRPOL, CRPS, LMCRPS y HMCRPS respectivamente. Los resultados mostraron que el fraccionamiento de CRPO puede ser útil en la preparación de fracciones ricas en nutracéuticos.

  14. 具有快速凝乳性能的水牛奶奶酪菌种筛选%Strains Screening for Rapid Milk Clotting of Buffalo Milk into Cheese

    Institute of Scientific and Technical Information of China (English)

    甘敏鑫; 吴健程; 刘兴胥; 吕军

    2016-01-01

    [Objective]The objective of this study is to screen strains that can produce cheese from buffalo milk and scalper milk.[Methods]Pure microbial species were isolated from the fresh buffalo milk and cattle milk,which could made buffalo milk coagulate from 4 to 6 h. Then their genetics stability,lactic acid content and diacetyl content were tested.[Results]With preliminary fermentation experiments,the strain 22 was chosen for further experi-ments,which showed strong acid-producing,high fragrance production,high viscosity and ap-propriate protein hydrolysate properties.[Conclusion]The results showed that the optimal fermentation condition is at 37℃,for 4.5 h.The resulting cheese has viscosity 109.2 Pa·S, acidity 47.3°T,diacetyl content 2.826×10-3 g/L and lactic acid 11.59%.%【目的】提高水牛奶产业的经济效益,为广西水牛奶奶酪工业化生产提供参考。【方法】采用平板筛选法从鲜水牛奶和黄牛奶中分离出能够生产水牛奶奶酪的菌种,对筛选到的菌株进行初步的发酵性能试验,并测定其传代稳定性、乳酸和双乙酰含量。【结果】筛选到1株能在4.5 h内使水牛奶凝固的菌株;该菌株在最佳发酵温度37℃下,经过厌氧发酵4.5 h即可使水牛奶完全凝固,所获得凝乳的黏度为109.2 Pa·S,酸度为47.3°T,双乙酰含量为2.826×10-3 g/L,乳酸含量为11.59%。【结论】该菌株产酸能力强、产香性能高、黏度和酸度大、有合适的蛋白质水解特性。

  15. Synthesis of 1,3-piperylene petroleum resin with AlCl3/SiO2 catalytic system%AlCl3/SiO2催化间戊二烯石油树脂的合成

    Institute of Scientific and Technical Information of China (English)

    高超; 王兰兰; 张龙

    2012-01-01

    采用溶液浸渍法制备了SiO2负载AlCl3催化剂,用AlCl3/SiO2作催化剂,合成了间戊二烯石油树脂.考察了载体预处理方式对负载量的影响及加入不同助催化剂对催化剂活性的影响,研究了催化剂组成对树脂产品性能的影响.结果表明:用H2O2预处理载体的负载量高于其他方法;CH4O3S为助催化剂时对催化活性的提高最明显.当n(CH4O3S)/n(Al)=0.10时,获得树脂的软化温度为105.1℃,色度为2,产品的收率达82.6%.该催化剂易与产物分离,并具有较好的重复使用性能.%The authors prepared a series of AlC13 catalysts supported on SiO2 via solution impregnation and synthesized 1,3-piperylene petroleum resin with the catalysts. A comprehensive study was performed with the focus on influence of pretreatment mode of the carrier on loading of A1C13, dependence of the catalysts' activity on adding different cocatalysts and correlation between properties of the resin products and composition of the catalysts. The results show that the SiO2 carrier pretreated with H2O2 has higher loading of A1C13 than its counterparts treated with other methods. The cocatalyst methanesulfonic acid(CH4O3S) gives rise to the most obvious increment in activity of the catalysts. In case the molar ratio of CH4O3S to Al is 0.1, the resultant 1,3-piperylene petroleum resin has a softening point of 105.1℃, color value of 2 and yield of 82.6%. The catalysts can be easily separated from the resin products and can be reused advantageously.

  16. 电子阴道镜检与TCT检测在宫颈病变筛查中的作用%Electronic Colposcopy and TCT Detected in The Screening of Scervical Lesions

    Institute of Scientific and Technical Information of China (English)

    高晓娅

    2012-01-01

      Objective:Explore digital colposcope and the membrane thin layer of liquid-based cytology (Thin-prep cytoLogy test,TCT) in the diagnosis of cervical disease, the clinical value. Methods:3980 cases of patients of colposcopy and TCT check and the results analyzed. Results:The electronic colposcopy chronic cervicitis, cervical polyps, genital warts and cervical cancer (cervical intraepithelial neoplasia-like lesions, CIN) CINⅠ, CIN II, CINⅢand pathological diagnosis coincidence rate of 94.1%, 100%, 93.5%, 92.3%, 81.4%, 79.9%and 54.1%;whole group of 3980 cases of TCT method and pathological examination method detection CINⅠof CIN II of CIN III and cervical cancer were 20.6%and 20.0%,. Both results are highly significant difference p<0.01 (x2=25.826). Conclusion:The digital colposcope and TCT on the diagnostic accuracy of cervical disease, especially the significance of cervical precancerous lesions and early cervical cancer screening.%  目的:探讨电子阴道镜和膜式薄层液基细胞学检查(Thin-prep cytoLogy test,TCT)在宫颈疾病诊断中的临床价值.方法:对3980例患者行电子阴道镜检查和TCT检查并对其结果进行分析.结果:电子阴道镜对慢性宫颈炎、宫颈息肉、尖锐湿疣、宫颈癌、(宫颈上皮内瘤样病变,CIN)CINⅠ、CINⅡ、CINⅢ的诊断与病理诊断符合率分别达94.1%、100.0%、93.5%、92.3%、81.4%、79.9%和54.1%;全组3980例TCT法和病理检查法检出CINⅠ、CINⅡ、CINⅢ和宫颈癌分别为17.4%和20.0%,二者结果比较有高度显著性差异p<0.01(x2=25.826).结论:电子阴道镜和TCT对宫颈疾病的诊断准确性高,尤其是对宫颈癌前病变和早期宫颈癌筛查具有重要意义.

  17. Clinical significance of communicable disease in patients with thoracic surgery and serum detection of tubercle bacillus%开胸患者血液传染性疾病与结核分枝杆菌检测的临床意义

    Institute of Scientific and Technical Information of China (English)

    刘颖; 王海滨; 靳海荣

    2011-01-01

    目的 探讨开胸患者血液传染性疾病与结核抗体相关指标检测的重要性,提高医务人员职业暴露防护对策,控制传染性疾病的传播.方法 选取行开胸手术的2216例患者(开胸组)与27087例门诊健康查体者(对照组),分别检测血液中HBsAg、抗-HCV、抗-HIV、梅毒(RPR),并对肺部阴影患者再查结核分枝杆菌(MTU).结果 开胸组、对照组中,HBsAg阳性率为8.26%、6.18%,抗-HCV阳性率为2.57%、0.94%,RPR阳性率为0.99%、0.05%,两组中肺部阴影患者MTU阳性率为10.31%、7.38%.结论 对开胸患者术前行传染性疾病及结核分枝杆菌相关指标的常规检测,可提高医护人员的职业安全与职业防护,预防医院感染,有效控制传染性疾病的传播.%OBJECTIVE To explore the clinical significance of communicable disease in patients with thoracic surgery, so as to improve the protective measure of medical staff and control the spread of communicable disease.METHODS A total of 2216 patients of thoracic surgery group and 27087 cases of healthy physical examination (control group), the serum markers such as HBsAg, anti-HCV, anti-HIV and RPR were detected. To the patients of lung shadow, the MTU was detected again. RESULTS Of the thoracic surgery and control groups, the positive rates of anti-HBsAg were 8.26% and 6.18 %, respectively. The positive rates of anti-HCV were 2. 57 %and 0. 94%, respectively. The positive rates of RPR were 0. 99% and 0. 05%, the positive rates of MTU were 10. 31 % and 7.38%. CONCLUSION The patient's serum of communicable disease and the MTU of lung shadow are detected routinely, which can significantly improve the occupational safety and defense, and prevent nosocomial infection and effectively control the spread of communicable disease.

  18. Facile synthesis and characterization of trimesic acid-Cu based metal organic frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Sahiner, Nurettin, E-mail: sahiner71@gmail.com [Canakkale Onsekiz Mart University, Faculty of Sciences and Arts, Department of Chemistry, Terzioglu Campus, 17100 Canakkale (Turkey); Nanoscience and Technology Research and Application Center (NANORAC), Terzioglu Campus, 17100 Canakkale (Turkey); Sel, Kivanc [Canakkale Onsekiz Mart University, Faculty of Sciences and Arts, Department of Physics, Terzioglu Campus, 17100 Canakkale (Turkey); Nanoscience and Technology Research and Application Center (NANORAC), Terzioglu Campus, 17100 Canakkale (Turkey); Ozturk, Omer Faruk; Demirci, Sahin; Terzi, Gozde [Canakkale Onsekiz Mart University, Faculty of Sciences and Arts, Department of Chemistry, Terzioglu Campus, 17100 Canakkale (Turkey)

    2014-09-30

    Graphical abstract: - Highlights: • Various MOFs based on trimesic acid (TMA) and various Cu (II) salts. • Benign preparation of TMA-Cu based MOFs in DI water and ethanol. • TMA-Cu MOFs with the mole ratio of Cu(II) to TMA varying between 1.5 and 2. • TMA-Cu MOF with conductivity values were 8.26E−08–5.29E−11 (S/cm). - Abstract: Metal-organic frameworks based on trimesic acid (TMA) as organic linker and Cu (II) as metal ions from different metal salts such as CuCl{sub 2}, Cu(NO{sub 3}){sub 2}, CuSO{sub 4} and Cu(CH{sub 3}COOH){sub 2} were prepared in relatively environmentally friendly media e.g., at room temperature in DI water and at the boiling point of ethanol. The prepared TMA-Cu MOFs showed very interesting porosity and optical coloring based on the source of the used metal salts and preparation medium. The prepared MOFs were characterized in terms of their porosity with BET measurements and it was found that about 850 m{sup 2}/g for the MOF prepared from Cu(NO{sub 3}){sub 2} salt in ethanol. The amounts of metal ions connected to TMA were determined by atomic absorption spectroscopy measurements (AAS) after dissolution of TMA-Cu MOFs by concentrated HCl treatments. From AAS measurements the mole ratio of Cu(II) to TMA was found to vary between 1.5 and 2, depending on the source of metal ions and the solvent used during preparation. The structural analysis and thermal characterization of the prepared MOFs were done by using FT-IR and TGA analysis, respectively. Additionally, TMA-Cu based MOF disks were prepared and their conductivities were determined by I–V measurements. The conductivity of TMA-Cu MOFs was calculated to be between 8.26E−08 and 5.29E−11 S/cm.

  19. 真稳态进动快速成像序列在肝内外胆管梗阻诊断中的价值%Value of balanced-FFE sequence in the diagnosis of inside and outside the liver bile duct obstruction

    Institute of Scientific and Technical Information of China (English)

    周永怀; 程和平; 曹若愚

    2009-01-01

    目的 探讨磁共振真稳态进动快速成像(balanced-FFE)序列在肝内外胆管梗阻诊断中的价值.方法 采用相控阵体线圈,对121例胆管疾病患者进行了balanced-FFE冠状位像扫描.结果 Balanced-FFE像对胆管结石定位准确率为96.6%,定性准确率为97.7%;对胆管肿瘤定位准确率为91.3%,定性准确率为82.6%.结论 Balanced-FFE序列不仅较准确地显示胆管内病变,而且能够显示胆管壁及周围组织侵犯情况,在肝内外胆管梗阻性疾病中具有较高的定位和定性诊断价值.%Objective To investigate the value of magnetic resonance balanced fast field echo (ba- lanced-FFE) sequcnce in the diagnosis of inside and outside the liver bile duct obstruction. Meth- ods Phased-array SENSE body coil was used. 121 cases of bile duct obstruction disease patients were scanned by balanced-FFE sequence with coronary scan. Results Balanced-FFE sequence image,showed that accuracy rate of the bile duct stones localization was 96.6%,accuracy rate of quality was 97.7%,accuracy rate of the bile duct tumor localization was 91.3%,accuracy rate of quality was 82.6%. Conclusion Balanced-FFE sequence can show not only the inside bile duct lesions exactly,but also bile duct wall and surrounding tissue invasion. It had more diagnosis ability of localization and quality with inside and outside the liver bile duct obstruction cases.

  20. 100例室性早搏患者临床治疗效果分析%Therapeutic Effect of Patients with Ventricular Premature Beat:an Analysis of 100 Cases

    Institute of Scientific and Technical Information of China (English)

    魏笑天

    2015-01-01

    目的:研究稳心颗粒与药物美托洛尔共同治疗室性早搏病症的效果。方法随机选取该院自2013年5月-2014年12月期间收治的100病例作为研究对象,随机分成对照组(47例)和观察组(53例),两组不再服用抗心律失常的药物,并以治疗原发病为基础,对照组患者口服药物美托洛尔片;观察组患者加用药物稳心颗粒。2个月为1个疗程。结果经过2个月治疗,观察组和对照组的总有效率分别为94.34%(50/53)、74.47%(35/47),该两组患者的治疗总效率对比,差异有统计学意义(χ2=7.826, P<0.05)。结论应用美托洛尔合并稳心颗粒可以有效治疗室性早搏,其疗效优于单用美托洛尔,值得临床推广。%Objective To study the therapeutic effect of wenxin granule combined with metoprolol in treating ventricular premature beat. Methods 100 patients admitted to our hospital between May 2013 and December 2014 were enrolled and randomized into control group(n=47) and observation group(n=53). All the patients stopped taking antiarrhythmic drugs, and based on the treatment of primary disease, they were given either oral metoprolol or wenxin granule combined with metoprolol for 2 months as one course. Results After treatment for 2 months, the total effective rate were 94.34%(50/53) in the observation group and 74.47%(35/47) in the control group, and there was statistically significant difference between them (χ2=7.826, P<0.05).Conclusion Wenxin granule combined with metoprolol is superior to metoprolol used singly in the treatment of ventricular premature beat, therefore it is worthy of clinical promotion.

  1. Factores de riesgo para infarto agudo de miocardio y prescripción de medicamentos para prevención secundaria

    Directory of Open Access Journals (Sweden)

    Desirée Sáenz-Campos

    2005-01-01

    Full Text Available Objetivo: tipificar algunos factores de riesgo coronario presentes en los pacientes que sobreviven a un primer infarto agudo de miocardio (IAM y describir el tratamiento farmacológico prescrito para profilaxis secundaria al egreso hospitalario. Métodos: estudio observacional, transversal y descriptivo, con información extraída del expediente clínico de 50 pacientes atendidos en 3 hospitales nacionales. Resultados: 42 varones y 8 mujeres, edad 63 ± 15 años, peso 67 ± 12 kg, Índice de Masa Corporal= 26.1 ± 2.1 kg/m², 38% hipertensos, 22% diabéticos (n= 8 pacientes con diabetes + hipertensión y 34% fumadores. Colesterol total 191 ± 45.7 mg/dL, colesterol-LDL 112 ± 33.8 mg/dL y colesterol-HDL 39.4 ± 8.26 mg/dL. Todos egresaron con medicamentos: 92% con antitrombóticos (predominó aspirina, 92% con estatinas, 78% con betabloqueador (atenolol o carvedilol, 70% con enalapril o losartán y 48% con nitratos. Conclusiones: este estudio piloto mostró que la enfermedad coronaria tiende a manifestarse desde la etapa de adulto joven, persiste en su mayor afectación a los varones y parecen prevalecer los factores de riesgo coronario modificables. Los antitrombóticos, beta- bloqueadores y las estatinas más frecuentemente prescritos.Objective: To describe some factors of coronary risk present in patients who survive a first acute myocardial infartion and the pharmacological treatment prescribed for secondary prevention. Methods: Observational, cross sectional and descriptive pilot study, information was obtained from the charts of 50 patients seen at 3 national hospitals. Results: 42 males and 8 women, age 63 ± 15 years, weight 67 ± 12 kg, Body Mass Index = 26.1 ± 2.1 kg/m², 38% hypertensive, 22% diabetic (n = 8 smokers patients with diabetes+hypertension and 34% smokers. Total cholesterol levels: 191 ± 45.7 mg/dL, cholesterol-LDL= 112 ± 33.8 mg/dL and cholesterol-HDL: 39.4 ± 8.26 mg/dL. The patients were prescribed: 92

  2. Francisella guangzhouensis sp. nov., isolated from air-conditioning systems.

    Science.gov (United States)

    Qu, Ping-Hua; Chen, Shou-Yi; Scholz, Holger C; Busse, Hans-Jürgen; Gu, Quan; Kämpfer, Peter; Foster, Jeffrey T; Glaeser, Stefanie P; Chen, Cha; Yang, Zhi-Chong

    2013-10-01

    Four strains (08HL01032(T), 09HG994, 10HP82-6 and 10HL1960) were isolated from water of air-conditioning systems of various cooling towers in Guangzhou city, China. Cells were Gram-stain-negative coccobacilli without flagella, catalase-positive and oxidase-negative, showing no reduction of nitrate, no hydrolysis of urea and no production of H2S. Growth was characteristically enhanced in the presence of l-cysteine, which was consistent with the properties of members of the genus Francisella. The quinone system was composed of ubiquinone Q-8 with minor amounts of Q-9. The polar lipid profile consisted of the predominant lipids phosphatidylethanolamine, diphosphatidylglycerol, phosphatidylglycerol, phosphatidylcholine, two unidentified phospholipids (PL2, PL3), an unidentified aminophospholipid and an unidentified glycolipid (GL2). The polyamine pattern consisted of the major compounds spermidine, cadaverine and spermine. The major cellular fatty acids were C10 : 0, C14 : 0, C16 : 0, C18 : 1ω9c and C18 : 1 3-OH. A draft whole-genome sequence of the proposed type strain 08HL01032(T) was generated. Comparative sequence analysis of the complete 16S and 23S rRNA genes confirmed affiliation to the genus Francisella, with 95 % sequence identity to the closest relatives in the database, the type strains of Francisella philomiragia and Francisella noatunensis subsp. orientalis. Full-length deduced amino acid sequences of various housekeeping genes, recA, gyrB, groEL, dnaK, rpoA, rpoB, rpoD, rpoH, fopA and sdhA, exhibited similarities of 67-92 % to strains of other species of the genus Francisella. Strains 08HL01032(T), 09HG994, 10HP82-6 and 10HL1960 exhibited highly similar pan-genome PCR profiles. Both the phenotypic and molecular data support the conclusion that the four strains belong to the genus Francisella but exhibit considerable divergence from all recognized Francisella species. Therefore, we propose the name Francisella guangzhouensis sp

  3. Purification technology of total flavonoids from Juglandis Mandshuricae Cortex by macroporous adsorptive resins%大孔树脂纯化核桃楸皮总黄酮工艺

    Institute of Scientific and Technical Information of China (English)

    杜瑞娟; 张聪璐; 梁宁; 李金凤; 侯晓虹

    2013-01-01

    目的 大孔树脂纯化核桃楸皮总黄酮的工艺优化.方法 以大孔树脂D-101、AB-8、NKA-2和HPD-826对总黄酮的吸附率和解吸率为指标筛选树脂种类,并对优选树脂的吸附特性和各影响因素进行研究,优化工艺条件.结果 AB-8具有较好的吸附率和解吸率,最佳纯化工艺为上样液的pH为7.0,总黄酮质量浓度为4.26 g·L-1,上样流速为0.9mL·min-1,洗脱溶剂为体积分数为50%的乙醇,洗脱体积为108 mL.经AB-8大孔树脂纯化1次后,核桃楸皮总黄酮含量提高至原来的3.12倍.结论 AB-8大孔树脂能较好地用于核桃楸皮总黄酮的纯化.%Objective To study the purification technology of total flavonoids from Juglandis Mandshuricae Cortex using macroporous adsorptive resins. Methods The adsorption and desorption capacity of four types of resins (D-101, AB-8, NKA-2, and HPD-826) for total flavonoids was investigated to select the optimal macroporous resin for our purpose. The adsorption characters and the influencing factors of the selected macroporous resin were also investigated to optimize the purification technology. Results AB-8 macroporous resin had the best property for the purification of total flavonoids. The optimized conditions were as follows: the pH of extracted solution was adjusted to 7, the concentration of total flavonoids was 4. 26 g o L-1, the flow rate was set at 0. 9 rnL·min-1 ,the elution reagent used was 50% (ψ) ethanol.and the volume of elu-tion was 108 mL. Under the optimized purification condition, the content of total flavonoids was increased by 3. 12 fold as compared with the original extraction. Conclusion AB-8 macroporous resin is suitable to refine total flavonoids from Juglandis Mandshuricae Cortex.

  4. Biodiversity and community composition of sediment macrofauna associated with deep-sea Lophelia pertusa habitats in the Gulf of Mexico

    Science.gov (United States)

    Demopoulos, Amanda W. J.; Bourque, Jill R.; Frometa, Janessy

    2014-11-01

    Scleractinian corals create three-dimensional reefs that provide sheltered refuges, facilitate sediment accumulation, and enhance colonization of encrusting fauna. While heterogeneous coral habitats can harbor high levels of biodiversity, their effect on the community composition within nearby sediments remains unclear, particularly in the deep sea. Sediment macrofauna from deep-sea coral habitats (Lophelia pertusa) and non-coral, background sediments were examined at three sites in the northern Gulf of Mexico (VK826, VK906, MC751, 350-500 m depth) to determine whether macrofaunal abundance, diversity, and community composition near corals differed from background soft-sediments. Macrofaunal densities ranged from 26 to 125 individuals 32 cm-2 and were significantly greater near coral versus background sediments only at VK826. Of the 86 benthic invertebrate taxa identified, 16 were exclusive to near-coral habitats, while 14 were found only in background sediments. Diversity (Fisher's α) and evenness were significantly higher within near-coral sediments only at MC751 while taxon richness was similar among all habitats. Community composition was significantly different both between near-coral and background sediments and among the three primary sites. Polychaetes numerically dominated all samples, accounting for up to 70% of the total individuals near coral, whereas peracarid crustaceans were proportionally more abundant in background sediments (18%) than in those near coral (10%). The reef effect differed among sites, with community patterns potentially influenced by the size of reef habitat. Taxon turnover occurred with distance from the reef, suggesting that reef extent may represent an important factor in structuring sediment communities near L. pertusa. Polychaete communities in both habitats differed from other Gulf of Mexico (GOM) soft sediments based on data from previous studies, and we hypothesize that local environmental conditions found near L. pertusa

  5. Kontribusi Model Pembelajaran Berbasis Proyek terhadap Faktor AIK dalam Pembelajaran Matematika Siswa Kelas II/3 SMPN 2 Makassar

    Directory of Open Access Journals (Sweden)

    Nasrullah Nasrullah

    2014-06-01

    Full Text Available AbstrakPenelitian ini bertujuan untuk menggunakan model pembelajaran berbasis proyek untuk meningkatkan antusiasme, intensitas aktivitas, dan kecakapan siswa dalam pembelajaran matematika. Untuk mencapai tujuan tersebut, penelitian tindakan kelas dipilih sebagai jenis penelitian yang berlangsung selama dua siklus. Setiap siklus memuat tahapan diantaranya: perencanaan, pelaksanaan tindakan, observasi, dan refleksi. Penelitian ini dilaksanakan di SMPN 2 Makassar, dengan subjek siswa kelas II/3 sebanyak 45 orang. Hasil penelitian menunjukkan bahwa kontribusi model pembelajaran berbasis proyek, bukan hanya meningkatkan antusiasme, intensitas, dan kecakapan siswa dalam mengikuti kegiatan pembelajaran matematika, tetapi juga membantu siswa dalam meningkatkan pemahaman terhadap materi pelajaran yang diberikan. Secara statistik, persentase antusiasme berubah dari 58,7% (sedang menjadi 80,7% (tinggi; persentase intensitas berubah dari 46,9% (kurang menjadi 77,3% (tinggi; persentase kecakapan berubah dari 18,7% (sangat kurang menjadi 64% (sedang. Kemudian rerata untuk hasil belajar siklus I ke siklus II meningkat dari 8,26 menjadi 8,27. Terdapat kenaikan 0,01. Kata kunci: Model Pembelajaran Berbasis Proyek, antusiasme, intensitas, dan kecakapan  AbstractThis study aims to apply project-based learning model to enhance enthusiasm, activity intensity, and students competencies on learning mathematics. Making this aim, classroom action research is chosen for two cycles. Each of cycle consist of planning, action, observation, and reflection. It was held at SMPN 2 Makassar with subject of 45 graders in class II/3. The result shows that contribution of the model, not only to trigger entushiasm, intensity, and competency in which students are engaging with activities of learning mathematics, but to facilitate students improving comprehension about subject matter. Statistically, the percentage of enthusiasm, intensity, and competencies are changing from 58

  6. Preparation and Properties of Interpenetrating Networks Absorbent Polymer Based on Polyaspartic Acid and Polyacrylic Acid%聚天冬氨酸/聚丙烯酸互穿网络吸水性树脂的制备及性能

    Institute of Scientific and Technical Information of China (English)

    赵彦生; 李倩; 刘永梅; 刘成岑; 龚吉安; 高洁荣

    2013-01-01

    Polyaspartic acid/ polyacrylic acid interpenetrating networks absorbent polymer(IPNAP) was prepared using crosslinked polyaspartic acid (PAsp) and acrylic acid(AAc) as the raw material, potassium peroxydisulfate as the initiator, N, N-methylene double acrylamide as the cross linking agents by two-step synthetic methods. The composition, structure and morphology of IPNAP were characterized by Fourier transform infrared spectrum(FT-IR) and scanning electron microscope(SEM) . Effects of composition on the absorbing properties of IPNAP were studied, while the absorbing properties of IPNAP in different salt solutions, different temperatures and different pH solutions were investigated. The results indicate that the composition of IPNAP affects the swelling capacity remarkably. When the mass ratio of PAsp to AAc is 1∶1, the swelling ratio of polymer gets the max which are 826 g/g and 120 g/g in distilled water and 0.9% NaC1 solution, respectively. It is found that the IPNAP exhibits the remarkable sensitivity to salt solutions, temperature and pH.%以交联聚天冬氨酸(PAsp)、丙烯酸(AAc)为原料,过硫酸钾为引发剂,N,N-亚甲基双丙烯酰胺为交联剂,采用分步法制备聚天冬氨酸/聚丙烯酸(PAAc)互穿网络吸水性树脂(IPNAP).利用红外光谱(FT-IR)和扫描电镜(SEM)对产物组成和结构形态进行了表征,探讨了组成对IPNAP吸液性能的影响,研究了IPNAP在不同盐溶液、温度及pH值条件下的吸液性能.结果表明,互穿网络组成对IPNAP吸液性能具有明显的影响,当PAsp/AAc质量比为1时,树脂的吸液性能最好,其在蒸馏水和生理盐水中的吸液倍率分别达到826g/g和120g/g,并且所制备的IPNAP对盐、温度和pH表现出显著的敏感性.

  7. Application of pure brilliance imaging in diagnosis of benign and malignant breast neoplasms%超声像素亮化处理技术在乳腺良恶性肿块诊断中的应用价值

    Institute of Scientific and Technical Information of China (English)

    董晓秋; 邵小慧; 胡成乙; 徐春媚

    2009-01-01

    Objective To evaluate the application of pure brilliance imaging(PB1) in diagnosis of benign and malignant breast neoplasms. Methods Ninty-seven breast neoplasms were respectively examined by high frequency ultrasound and PBI before operation,then correlated with pathological results. Results The accuracy of high frequency ultrasound for breast neoplasms was 73.2% with the sensitivity 77.8% ,specificity 69.2%. The detectable rate of spiculate margin, halo,calcification were much higher in PBI than those in high frequency ultrasound(P<0.05). And the accuracy,sensitivity and specificity of PBI were 86.6%, 91.1%, 82.6%. Conclusions PBI can significantly increase the detectable rate of ultrasonographie marginal features of breast neoplasms which were also helpful to the differential diagnosis.%目的 评价超声像素亮化处理技术(pure brilliance imaging,PBI)在乳腺良恶性肿块诊断中的应用价值.方法 对97个乳腺肿块分别使用高频超声和PBI进行术前检查,并与术后病理结果对照.结果 高频超声检查诊断的敏感性、特异性和准确性分别为77.8%、69.2%、73.2%,应用PBI后,乳腺肿块毛刺状边缘、"晕环"及钙化的检出率较高频超声检查明显提高(P<0.05),诊断的敏感性、特异性和准确性分别为91.1%、82.6%、86.6%.结论 超声PBI可明显提高乳腺肿块超声图像边缘特征的检出率,有助于乳腺良恶性肿块的鉴别诊断.

  8. 社会支持与急诊护士离职意愿的相关性研究%The relationship between social support and turnover intention among emergency nurses

    Institute of Scientific and Technical Information of China (English)

    雷望安; 何静; 姚荷英

    2013-01-01

    Objectives:To explore the effect of social support on emergency nurses' turnover intention,and to analyze the causes of turnover intention.Methods:We recruited 82 emergency nurses by cluster sampling method and investigated them by demographic questionnaire,Social Support Rating Scale (SSRS),and Turnover Intention Scale (TIS).Results:The mean score of TIS was 14.79±4.19,which was in a high level.The scores of total scale and each dimension of social support were negatively correlated to the total score of turnover intention (P<0.05) The dimension of support unilization had maximum effect to turnover intension (B=-0.826).Conclusion:We should pay more attention to the weak points of three dimensions of social support by increasing nurses' social support from,cultivating their subjective feelings,and improving their support utilization to construct the effective social support system and to reduce nurses'turnover intention.%目的:探讨社会支持对急诊护士离职意愿的影响,分析其离职意愿产生的原因.方法:采用整群抽样法,对急诊科82名护士应用一般情况调查表、社会支持评定量表(SSRS)、离职意愿调查表(TIS)进行调查.结果:离职意愿均值为(14.79±4.19)分,处于较高水平.社会支持总分与离职意愿呈负相关(P<0.05);社会支持各维度与离职意愿均呈负相关(P<0.05),其中对支持的利用度影响最大(B=-0.826).结论:针对社会支持三维度的薄弱点,增加急诊护士的社会支持,培养其主观感受性,增进对支持的利用,构建有效的社会支持系统,降低急诊护士的离职意愿.

  9. 气相色谱-质谱法测定食品中邻苯二甲酸酯%GC-MS Determination of Phthalates in Food

    Institute of Scientific and Technical Information of China (English)

    苏晓; 王修鹏; 王岩

    2012-01-01

    提出了气相色谱-质谱法测定食品中16种邻苯二甲酸酯(PAE’s)含量的方法。详细叙述了不同基质的食品的处理方法,高脂类样品需经凝胶渗透色谱净化。采用HP-5MS石英毛细管柱进行分离和电子轰击离子源质谱检测。16种PAE’S的线性范围为0.50-20.0mg·L^-1,检出限(3S/N)在6.03-826μg·kg^-1之间。在1,10mg·kg^-1两个浓度水平进行加标回收试验,纯油脂和高脂固体样品中16种PAE’S的平均回收率分别在79.2%~101%和77.8%~97.4%之间,测定值的相对标准偏差(n=6)分别在3.4%~6.9%和4.1%~6.0%之间。%A method of GC-MS for the determination of 16 phthalates (PAE's) in food was proposed. The pretreatment methods for different matrixes of samples were described in detail, and the high-fatty food was purified by gel permeation chromatography (GPC). HP-5MS quartz capillary column was used for separation, and E1 source was used for determination in MS. Linearity ranges of the 16 PAE's were kept in the same range of 0. 50- 20. 0 mg . L^-1 , with detection limits (3S/N) ranged from 6.03 to 826μg .kg^-1. Tests for recovery were made at the concentration levels of 1 and 10 mg. kg^-1 of the mixed phthalate standards, values of recovery found were in the ranges of 79.2%--101% for pure oil and fat and 77. 8%-97. 4% for high-fatty food. Values of RSD's (n=3) found were in the ranges of 3.4%-6. 9% and 4. 1%-6.0% respectively.

  10. 红蓝光联合陈氏粉刺清治疗痤疮的疗效观察%Therapeutic effect of acne treated by red and blue light combine with Chen's Acne Clear

    Institute of Scientific and Technical Information of China (English)

    林湘群; 李为儒

    2011-01-01

    探讨联合应用红蓝光及陈氏粉刺清治疗炎症性痤疮的临床效果.方法:选择中重度(Pillsbury分级为Ⅱ或Ⅲ度)寻常性痤疮92例,随机分为试验组(46例)和对照组(46例).试验组采用红蓝光与陈氏粉刺清联合治疗,对照组单用陈氏粉刺清治疗,研究分析其治疗效果.结果:总体效果评价中,试验组痊愈率为21.7%,有效率为82.6%;对照组痊愈率为10.8%,有效率为54.3%,比较两组之间痊愈率及有效率均有显著性差异(P<0.05).结论:红蓝光与粉刺清联合治疗炎症性痤疮疗效好,其疗效明显优于单用粉刺清治疗,不良反应亦轻微.%Objective To evaluate the clinical therapeutic effect of the red and blue light combine with Chen's acne clear for acne. And to explore the therapeutic effect. Methods Choose moderate to severe (Pillsbury classification of Ⅱ or Ⅲ degree) of acne vulgaris 92 patients, Divided into experimental group (46 cases) and control group (46 cases) randomly. Experimental group were treated with red and blue combined with Chen's acne Clear, control group only were treated with Chen's Acne clear, Observe and evaluate its therapeutic effect. Results The cure rate was 21.7%, the effective rate was 82.6% in experimental group, the cure rate was 10.8% and the effective rate was 54.3% in control group, between the two groups, cure rates and efficiency rates were with statistical significance (P<0.05).Only one case appeared skin turn red. Conclusion Combination Red and blue Light and Chen's Acne Clear therapy for inflammatory acne seems to be superior to use Chen's Acne Clear alone, and side effects were minimal

  11. Clinical predictors of colorectal polyps and carcinoma in a low prevalence region:Results of a colonoscopy based study

    Institute of Scientific and Technical Information of China (English)

    Yousef Bafandeh; Manoochehr Khoshbaten; Amir Taher Eftekhar Sadat; Sara Farhang

    2008-01-01

    AIM:To estimate the prevalence of colorectal cancer (CRC) in patients with long lasting colonic symptoms undergoing total colonoscopy;and to establish clinical features predicting its occurrence.METIHODS:This prospective study was carried out in Imam Hospital,Tabriz University of medical sciences,Iran.Continuous patients with long lasting lower gastrointestinal tract symptoms who had the criteria of a colonoscopy were included.The endoscopist visualized the caecum documented by a photo and/or a specimen from terminal ileum.RESULTS:Four hundred and eighty consecutive symptomatic patients [mean age (SD):42.73 (16.21)]were included.The prevalence of colorectal neoplasia was 15.3%(34 subjects) and 37.7% (181 subjects)had a completely normal colon.Adenomatous polyps were detected in 56 (11.7%) patients,in 12.3% of men and 10.9% of women.The mean age of the patients with a polyp was significantly higher than the others (49.53±14.16 vs 41.85±16.26,P=0.001).Most of the adenomatous polyps were left sided and tubular;only 22.5% of polyps were more than 10 mm.Cancer was detected in 16 (3.6%) of our study population,which was mostly right sided (57.2%).The mean age of patients with cancer was significantly higher than the others (60.25±8.26 vs 42.13±16.08,P<0.005) and higher than patients with polyps[60.25 (8.26) vs 49.53 (1.91) (P<0.0005)].None of the symptoms (diarrhea,abdominal pain,rectal bleeding,constipation,altering diarrhea and constipation,history of cancer,known irritable bowel disease,history of polyp and fissure or family history of cancer) were predictors for cancer or polyps,but the age of the patient and unexplained anemia independently predicted cancer.CONCLUSION:Less advanced patterns and smaller sizes of adenomas in Iran is compatible with other data from Asia and the Middle East,but in contrast to western countries.Prevalence of colonic neoplasia in our community seems to be lower than that in western population.Colonic symptoms are not predictors

  12. Compatibilidad entre nueve cepas de Biomphalaria glabrata de áreas endémicas y no endémicas y una cepa de Schistosoma mansoni venezolanas

    Directory of Open Access Journals (Sweden)

    Pino Luz A.

    1999-01-01

    Full Text Available Se infectaron experimentalmente 9 lotes de 32 caracoles B. glabrata (de 5 a 7mm de diámetro con miracidios de la cepa C5 de Schistosoma mansoni a razón de 5 miracidios por caracol, pertenecientes a las siguientes cepas: En el área endémica de transmisión de Esquistosomiasis mansoni a Sector Puerta Negra, Lago Valencia, b Cagua c Ingenio Bolívar (Estado Aragua d Mariara e Caserío El 25 f Güigüe (Estado Carabobo. Fuera del área endémica de transmisión g Anzoátegui (Estado Lara, h Chabasquén (Estado Portuguesa, i Sector La Elvira, Caripe (Estado Monagas. El período prepatente intramolusco, osciló entre 23 y 25 días, para las 9 cepas evaluadas. La duración total de la infección fue muy variable desde 20 días para la cepa Chabasquén, hasta 93 días para la de Güigüe.La producción total promedio de cercarias al tercer día de iniciada la emisión varió desde X = 74,4 para la cepa de Mariara, hasta X = 591,7 para la cepa de Chabasquén. Se evidenció la existencia de diferencias estadísticamente significativas (H = 97,4, P < 0,05 en la producción total de cercarias al tercer día de iniciada la emisión, detectándose diferencias estadísticamente significativas para casi todas las 36 combinaciones, excepto para las cuatro siguientes: Mariara/Ingenio Bolívar, Cagua/Caserío El 25, Lago de Valencia/Güigüe y Güigüe/Caripe.En lo que respecta al porcentaje de caracoles que presentaron cura espontánea, los valores mas elevados se obtuvieron en las cepas del Lago de Valencia (88,8%, Cagua (85,2%, Chabasquén (82,6%, Caripe (82,6% y Anzoátegui (80%. Mientras que el porcentaje mas bajo se obtuvo para la cepa de Güigüe (21,4%.

  13. The Relationship between the Viscosity and Fraction Characteristcs of the Heavy Oil of Shengli Oil Field%胜利油田稠油黏度与其组分性质的关系研究

    Institute of Scientific and Technical Information of China (English)

    盖平原

    2011-01-01

    选取黏度分别属于普通稠油、特稠油、超稠油、特超稠油的GD排15-0、GD排13-10、单56-16-10、56-9-11、单113-P1、郑411系列、坨826系列等13个胜利油田稠油样品,利用液相色谱法将其分离成饱和分、芳香分、胶质、沥青质四个组分;采用VPO法分别测定各组分的平均相对分子质量;采用元素分析仪和原子吸收光谱仪测定其元素组成与金属含量.研究结果表明,沥青质含量是影响稠油黏度的主要因素,胶质含量对原油黏度也有重要影响,稠油黏度随胶质、沥青质总量增大而增加;胶质沥青质组分的高相对分子质量是其影响体系黏度的主要原因;组分杂原子含量和金属元素含量对稠油黏度均有一定影响.%The 13 samples including CD Pail 5-0, CD Pail 3-10, Shan 56-16-10, 56-9-11, Shan 113-P1, Zheng 411 and Tuo 826, which were classified into ordinary heavy oil, heavy oil, extra heavy oil and super-heavy oil, were fractioned into four components of saturates, aromatics, resins, and asphaltenes by liquid chromatogram.The relative molecular mass of fractions was measured by VPO method, and the element composition and the mental content of fractions were measured by elemental analysis and atomic absorption spectrometry.It could be concluded that the content of asphaltenes and resins played a decisive role in the viscosity of heavy oil.The viscosity of the heavy oil would be great if the content of resins and asphaltenes was high.The high relative molecular mass was the main reason for the resins and asphaltenes impacting the viscosity of the samples.The viscosity of heavy oil was also affected by the content of heteroatom or metals of fraction.

  14. Proceso de elaboración de yogur deslactosado de leche de cabra Processo para elaboração de iogurte deslactosado de leite de cabra

    Directory of Open Access Journals (Sweden)

    Virginia Antonieta Rodriguez

    2008-12-01

    Full Text Available El objetivo de este trabajo fue desarrollar un proceso para la elaboración de yogur deslactosado de leche de cabra, realizando en forma simultánea la hidrólisis de la lactosa y la fermentación. Se utilizaron tres dosis de una β-galactosidasa ácida de origen fúngico (Aspergillus oryzae: 1253, 2506 y 3759 unidades/L, usando como referente una muestra sin enzima. Luego de una incubación de 5 horas a 38 °C y posterior conservación durante 24 horas a 4 °C, se determinaron las concentraciones de glucosa, galactosa, lactosa, pH y acidez titulable. Teniendo en cuenta una concentración de lactosa en leche de 4,42 g.100 mL-1, el mayor porcentaje de hidrólisis obtenido en el yogur (82,6%, p O objetivo deste trabalho foi desenvolver um processo para a elaboração de iogurte deslactosado de leite de cabra, realizando de forma simultânea a hidrólise da lactose e a fermentação. Utilizaram-se três doses de uma β-galactosidase ácida de origem fúngica (Aspergillus oryzae: 1253, 2506 e 3759 unidades/L, usando como referente uma amostra sem enzima. Após uma incubação de 5 horas a 38 °C e posterior conservação durante 24 horas a 4 °C, determinaram-se as concentrações de glicose, galactose, lactose, pH e acidez titulável. Considerando uma concentração de lactose em leite de 4,42 g.100 mL-1, a maior porcentagem de hidrólise obtida no iogurte (82,6%, p < 0,0001 foi conseguida com 2506 unidades/L de enzima, enquanto que sem o agregado de enzima a porcentagem foi de 48,5%. Conclui-se que o processo utilizado permitiria, somente numa etapa, a elaboração de um iogurte que além de ter as propriedades hipoalergênicas e nutricionais próprias do leite de cabra, por seu baixo conteúdo de lactose, se converteria num alimento de características funcionais de grande utilidade para aquelas pessoas que padecem intolerância ao açúcar do leite.

  15. Mechanism of Maize Root Morphology Change Induced by Arbuscular Mycorrhizal Fungi%丛枝菌根真菌诱导玉米根系形态变化及其机理

    Institute of Scientific and Technical Information of China (English)

    黄京华; 刘青; 李晓辉; 曾任森; 骆世明

    2013-01-01

    Maize cultivar GY115 and ZD619 were used for experimental materials cultured in pot and field re-spectively.The effects of Glomus mosseae and G. versiforme on root morphology and root endogenous growth hormone content of maize(Zea mays) were studied. The results showed that the morphology of mycorrhizal maize roots signifi-cantly changed, root number increased after mycorrhization. Furthermore, the difference between mycorrhizal and non-mycorrhizal roots increased with the development of mycorrhizal infection rate. When grew 60 days, mycorrhizal maize total root length per plant of 788.61 cm, fresh root weight per plant of 8.26 g, were significantly higher than non-mycorrhizal root. Growth hormone content in roots increased with mycorrhizal infection rate increasing, and the content of IAA in inoculation treatment was higher than control significantly. This study indicated that AM fungi can induce the growth hormone content increased in maize roots, enhance root number, and thereby increase the root sur-face of nutrient absorption to improve plant growth.%  以高油115和正大619为实验材料,分别通过盆栽和田间试验研究接种摩西球囊霉和地表球囊霉对玉米根系形态和根系内源生长素含量的影响。结果表明,玉米形成菌根后根系形态明显改变,根条数显著多于对照,并且接种处理与对照间的差异随菌根侵染率的上升而加大,差异极显著。生长60 d时,有菌根的玉米单株总根长度为788.61 cm,根系重量达8.26 g,均显著高于无菌根的对照。根系生长素含量随菌根侵染率上升而增加,并且显著高于不接种的对照。丛枝菌根真菌侵染可以促使玉米根内生长素含量上升,根条数增多,增加吸收面积,促进玉米生长。

  16. 轮状病毒与腺病毒联合检测在婴幼儿腹泻诊断中的应用研究%Application study on combinded detection of rotavirus and adenovirus in diagnosis of infantile diarrhea

    Institute of Scientific and Technical Information of China (English)

    张家超; 查长森; 吴伟锋

    2015-01-01

    Objective:To study the application of combined detection of rotavirus and adenovirus in diagnosis of infantile diarrhea.Methods:The results of the detection of rotavirus (Rotavirus) and adenovirus (Adenovirus) were collected from 9686 cases of infants with diarrhea in our hospital from August 2013 to August 2015, and the effect of Adenovirus and Rotavirus combined detection in the diagnosis of infantile diarrhea was observed and analyzed.Results:The positive rate of adenovirus infection was 8.26%, which was significantly lower than that of the combined detection of 44.74%, and the difference was statistically significant (P0.05) between the two and the.Conclusions: Conclusion: combined detection of rotavirus (Rotavirus) and adenovirus (Adenovirus) in the diagnosis of diarrhea in children, it has a good effect, it is worthy of further clinical promotion.%目的:研究轮状病毒与腺病毒联合检测在婴幼儿腹泻诊断中的应用情况.方法: 收集2013年8月-2015年8月在我院儿科门诊及住院的9686例婴幼儿腹泻患者的轮状病毒(Rotavirus)和腺病毒(Adenovirus )的检测结果,观察和分析Rotavirus与Adenovirus 联合检测在婴幼儿腹泻诊断中的应用效果.结果:腺病毒检测感染阳性率为8.26%,明显低于联合检测的44.74%,差异具有统计学意义(P0.05).结论:将轮状病毒(Rotavirus)和腺病毒(Adenovirus )联合检测应用于儿童腹泻的诊断中,有良好的效果,值得临床上进一步推广.

  17. Soil oil content hyperspectral model in Gudong Oilfield%孤东油田土壤石油类含量的高光谱反演模型

    Institute of Scientific and Technical Information of China (English)

    樊彦国; 张磊

    2012-01-01

    土壤中石油类含量的检测对石油污染的预防与治理具有重要的实际意义.本文首先进行孤东油田土壤样品高光谱反射率的室内测定及石油含量的检测,然后利用单变量预测模型和逐步回归方法分析了土壤光谱特征参数与石油类含量之间的线性和非线性关系,结果表明:包络线分析的第三折线段斜率与石油类含量相关性最好,该段斜率的三次曲线函数为石油类含量的最佳单变量估算模型.标准正态变量变换对光谱的预处理效果最好,利用变换后光谱建立多元模型,其调整的判定系数(R2)是0.826,总均方根RMSE是0.531,且自变量个数较少,为最优预测模型.本文提出的利用高光谱数据检测土壤中石油类含量的方法,为土壤石油类污染检测提供了一种有效的新思路.%The detection of oil content in soil has an important practical significance in oil pollution prevention and control. We measure the hyperspectral reflectivity and the oil content for soil samples in Gudong Oilfield. Using variable forecast model and stepwise regression method, we analyze the linear and nonlinear relationships between soil spectral characteristic parameters and oil content. The experiment shows that there is a significant correlation between the third broken line segment slope of envelope line analysis and the oil content. The cubic function of this section slope is the best single variate estimation model. The standard normal variate transformation has the best effect on spectrum pretreatment. When the transformed spectral are used to build mul-tivariate regression model, the adjusted coefficient of determination R2 is 0.826, and the total RMSE is 0.531, which is the best forecast model. The method of using hyperspectral data to detect the oil content will provide an effective new way for detecting the oil pollution in soil.

  18. Perfil linguístico, familial e do gênero de escolares com diagnóstico de dislexia de uma clínica escola

    Directory of Open Access Journals (Sweden)

    Nathane Sanches Marques Silva

    2014-04-01

    Full Text Available Objetivo traçar o perfil dos pacientes com diagnóstico de dislexia quanto ao gênero, recorrência familial para distúrbios da comunicação ou dificuldade escolar, presença de alteração de linguagem oral e quanto à presença de alteração nas habilidades de memória de trabalho fonológica, memória visual e consciência fonológica na primeira avaliação fonoaudiológica, por meio da análise de prontuários de indivíduos. Métodos foi realizado um estudo transversal retrospectivo por meio de análise de prontuários dos últimos dez anos, no período de 2001 a 2011, em que foram investigadas as histórias clínicas e a primeira avaliação interdisciplinar de pacientes diagnosticados com dislexia. Resultados por meio de uma amostra de 23 prontuários, foi verificado que 82% dos pacientes pertencem a indivíduos do gênero masculino; 60,9% possuíam recorrência familial quanto à presença de familiares com distúrbios da comunicação ou dificuldades escolares; 47,8% dos escolares com diagnóstico de dislexia relataram sofrer de algum tipo de alteração de linguagem oral; 82,6% dos pesquisados possuíam alteração de memória de trabalho fonológica; 82,6% de consciência fonológica e 39,1% de memória visual. Conclusão o perfil dos pacientes diagnosticados com dislexia, na Clínica Escola da instituição de origem, se caracteriza, preferencialmente pelo gênero masculino, pela presença de recorrência familial para distúrbios da comunicação ou dificuldades escolares e por apresentarem alteração de memória de trabalho fonológica e consciência fonológica durante a primeira avaliação fonoaudiológica.

  19. How stem defects affect the capability of optimum bucking method?

    Directory of Open Access Journals (Sweden)

    Abdullah Emin Akay

    2015-07-01

    Full Text Available In forest harvesting activities, computer-assisted optimum bucking method increases the economic value of harvested trees. The bucking decision highly depends on the log quality grades which mainly vary with the surface characteristics such as stem defects and form of the stems. In this study, the effects of stem defects on optimum bucking method was investigated by comparing bucking applications which were conducted during the logging operations in two different Brutian Pine (Pinus brutia Ten stands. In the applications, the first stand contained the stems with relatively more stem defects than that of the stems in the second stand. The average number of defects per log for sample trees in the first and the second stand was recorded as 3.64 and 2.70, respectively. The results indicated that optimum bucking method increased the average economic value of harvested trees by 15.45% and 8.26 % in the stands, respectively. Therefore, the computer-assisted optimum bucking method potentially provides better results than that of traditional bucking method especially for the harvested trees with more stem defects.

  20. Color-tunable photoluminescence phosphors of Ce3+ and Tb3+ co-doped Sr2La8(SiO4)6O2 for UV w-LEDs

    Science.gov (United States)

    Guo, Qingfeng; Liao, Libing; Mei, Lefu; Liu, Haikun; Hai, Yun

    2015-05-01

    A series of new luminescent emission-tunable phosphors Sr2La8(SiO4)6O2:Ce3+, Tb3+ with apatite structure have been synthesized by a high temperature solid-state reaction. The phase structure, photoluminescence emission and excitation spectra, lifetime, as well as the effect of Tb3+ concentration are investigated to characterize the resulting samples. The critical distance was calculated to be 8.26 Å by using the concentration quenching method. The intense green emission was observed in the Sr2La8(SiO4)6O2:Ce3+, Tb3+ phosphors on the basis of the efficient energy transfer from Ce3+ to Tb3+ with an efficiency of 68.55%. And a possible mechanism of the energy-transfer from Ce3+ to Tb3+ ion is also proposed. The results indicate that Sr2La8(SiO4)6O2:Ce3+, Tb3+ phosphors have potential applications to be used as near UV-convertible phosphors for white light-emitting diodes because of the broad excitation in the near-ultraviolet range and the efficient green emission light.

  1. Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice.

    Science.gov (United States)

    Ghaffari-Nazari, Haniyeh; Tavakkol-Afshari, Jalil; Jaafari, Mahmoud Reza; Tahaghoghi-Hajghorbani, Sahar; Masoumi, Elham; Jalali, Seyed Amir

    2015-01-01

    Peptide-based vaccines are attractive approaches for cancer immunotherapy; but the success of these vaccines in clinical trials have been limited. Our goal is to improve immune responses and anti-tumor effects against a synthetic, multi-epitope, long peptide from rat Her2/neu (rHer2/neu) using the help of CD4+ T cells and appropriate adjuvant in a mouse tumor model. Female BALB/c mice were vaccinated with P5+435 multi-epitope long peptide that presents epitopes for cytotoxic T lymphocytes (CTL) in combination with a universal Pan DR epitope (PADRE) or CpG-oligodeoxynucleotides (CpG-ODNs) as a Toll-like receptor agonist adjuvant. The results show that vaccination with the multi-epitope long peptide in combination with the PADRE peptide and CpG-ODN induced expansion of subpopulations of CD4+ and CD8+ cells producing IFN-γ, the average tumor size in the vaccinated mice was less than that of the other groups, and tumor growth was inhibited in 40% of the mice in the vaccinated group. The mean survival time was 82.6 ± 1.25 days in mice vaccinated with P5+435 + CpG+ PADRE. Our results demonstrate that inclusion of PADRE and CpG with the peptide vaccine enhanced significant tumor specific-immune responses in vaccinated mice. PMID:26556756

  2. Current trends in treatment outcomes of orbital cellulitis in a tertiary hospital in Southern Nigeria

    Directory of Open Access Journals (Sweden)

    Odarosa M Uhumwangho

    2016-01-01

    Full Text Available Background: Orbital cellulitis refers to the inflammation or infection of the soft tissues of the orbit located behind the orbital septum. Aim: To determine the current trends in the outcomes following the management of orbital cellulitis in a tertiary hospital in Southern Nigeria. Patients and Methods: A retrospective review of medical records of patients with orbital cellulitis from January 2008 to December 2014 was conducted. The age, sex, duration of symptoms, predisposing factors, clinical findings, laboratory/radiological investigations, treatment provided, complications, and follow-up were recorded. Results were analyzed with SPSS Version 21 program. Results: Forty-two patients were seen made of 17 (40.5% males and 25 (59.5% females with a mean age of 18.2 ± 18.7 years of which children 6/18 at presentation, 38 (82.6% and at discharge, 39 (84.8%. The mean duration of presenting complaints was 15.5 ± 31.6 days. Patients who presented early were less likely to develop complications, P = 0.003. The most common complication was exposure keratopathy in 8 (44.4% eyes. The only surgical intervention performed was incision and drainage of abscess in 3 (7.1% eyes. No patient came for follow-up. Conclusion: Prompt institution of effective antibiotics and management of complications that may arise improves prognosis of orbital cellulitis.

  3. Evaluation of global synchronization for iterative algebra algorithms on many-core

    KAUST Repository

    ul Hasan Khan, Ayaz

    2015-06-01

    © 2015 IEEE. Massively parallel computing is applied extensively in various scientific and engineering domains. With the growing interest in many-core architectures and due to the lack of explicit support for inter-block synchronization specifically in GPUs, synchronization becomes necessary to minimize inter-block communication time. In this paper, we have proposed two new inter-block synchronization techniques: 1) Relaxed Synchronization, and 2) Block-Query Synchronization. These schemes are used in implementing numerical iterative solvers where computation/communication overlapping is one used optimization to enhance application performance. We have evaluated and analyzed the performance of the proposed synchronization techniques using Jacobi Iterative Solver in comparison to the state of the art inter-block lock-free synchronization techniques. We have achieved about 1-8% performance improvement in terms of execution time over lock-free synchronization depending on the problem size and the number of thread blocks. We have also evaluated the proposed algorithm on GPU and MIC architectures and obtained about 8-26% performance improvement over the barrier synchronization available in OpenMP programming environment depending on the problem size and number of cores used.

  4. Operational safety and experience monitoring safety systems performance during operation at Bruce Nuclear Generating Station A (Bruce N.G.S. A)

    International Nuclear Information System (INIS)

    Bruce N.G.S. A is a four 826 MWe CANDU (PHWR) unit station. Each reactor unit has two independent Shutdown Systems, Shutdown System One (SDS1) with 30 gravity dropped neutron absorbing rods and Shutdown System Two (SDS2) with Liquid Neutron Poison Injection System. At present there is a High Pressure Emergency Core Injection System (HPECI) common to two units and a Low Pressure Emergency Core Injection System (LPECI) common to the other two. The latter will be replaced by the HPECI which will be the Emergency Core Injection System for all the four reactor units by 1986. There is a single Negative Pressure Containment System (NPC) which is common to all four reactor units. To ensure that each of the five safety systems mentioned above will operate effectively when called upon, an ongoing comprehensive monitoring program is carried out by the operations staff at the station. The main element of this program consists of a battery of safety system tests, designed to test the operation of one or group of components without firing the system

  5. Stability Analysis of Superconducting Electroweak Vortices

    CERN Document Server

    Garaud, Julien

    2010-01-01

    We carry out a detailed stability analysis of the superconducting vortex solutions in the Weinberg-Salam theory described in Nucl.Phys. B826 (2010) 174. These vortices are characterized by constant electric current $I$ and electric charge density $I_0$, for ${I}\\to 0$ they reduce to Z strings. We consider the generic field fluctuations around the vortex and apply the functional Jacobi criterion to detect the negative modes in the fluctuation operator spectrum. We find such modes and determine their dispersion relation, they turn out to be of two different types, according to their spatial behavior. There are non-periodic in space negative modes, which can contribute to the instability of infinitely long vortices, but they can be eliminated by imposing the periodic boundary conditions along the vortex. There are also periodic negative modes, but their wavelength is always larger than a certain minimal value, so that they cannot be accommodated by the short vortex segments. However, even for the latter there re...

  6. 香菇多糖磷酸化修饰工艺条件的研究%Study on the Optimal Phosphorylation of Lentinan

    Institute of Scientific and Technical Information of China (English)

    张难; 吴远根; 莫莉萍; 邱树毅; 王文平

    2007-01-01

    研究了制备磷酸化香菇多糖的工艺条件.通过单因素实验,考察磷酸化试剂、温度、时间、pH值对修饰后香菇多糖磷酸根接枝量、粘度的影响,确定最佳磷酸化工艺条件为:质量分数分别为5%三聚磷酸钠(STPP)和2%三偏磷酸钠(STMP)混合液作为磷酸化试剂,温度90℃,时间5 h,pH9.0,所得磷酸化香菇多糖衍生物的磷 酸根接枝量为6.826%.红外光谱分析结果证实,修饰后的香菇多糖含有磷酸酯基团.粘度测定表明,香菇多耱经磷酸化修饰后的粘度基本没有变化.

  7. PREPARATION AND PARTIAL PHYSICOCHEMICAL PROPERTY STUDY OF PHOSPHORYLATED LENTINAN%磷酸化香菇多糖的制备及其部分理化性质的研究

    Institute of Scientific and Technical Information of China (English)

    张难; 邱树毅; 吴远根; 莫莉萍; 王文平

    2008-01-01

    研究了制备磷酸化香菇多糖的工艺条件及其部分理化性质.通过单因素实验,考察磷酸化试剂、温度、时间、pH值对修饰后香菇多糖磷酸根接枝量、黏度的影响,确定最佳磷酸化工艺条件为:5%三聚磷酸钠(STPP)和2%三偏磷酸钠(STMP)混合液作为磷酸化试剂,温度90℃,时间5h,pH值9.O,所得磷酸化香菇多糖衍生物的磷酸根接枝量为6.826%.同时对修饰前后香菇多糖的理化性质进行分析,红外光谱表明磷酸基团已被接枝上且多糖性质无较大变化.

  8. Correlation between serum reactivity to Demodex-associated Bacillus oleronius proteins, and altered sebum levels and Demodex populations in erythematotelangiectatic rosacea patients.

    Science.gov (United States)

    Jarmuda, Stanislaw; McMahon, Fred; Zaba, Ryszard; O'Reilly, Niamh; Jakubowicz, Oliwia; Holland, Ashling; Szkaradkiewicz, Andrzej; Kavanagh, Kevin

    2014-02-01

    Rosacea is a chronic inflammatory condition that affects the skin of the face and the eyes. The aetiology of rosacea is not clearly established but increasing evidence suggests a potential role for bacteria in the induction of the condition. A role for Bacillus oleronius, originally isolated from within a Demodex folliculorum mite, in the aetiology of the condition has been suggested. The aim of the study was to determine whether a correlation existed between the level of sebum and the density of D. folliculorum in the skin of erythematotelangiectatic rosacea patients, and the reactivity of these patients' sera to proteins of B. oleronius. Serum reactivity to the 62 and 83 kDa B. oleronius proteins was found in 82.6 % (62/75) of the rosacea patients and in 26.9 % (14/52) of controls (P = 0.0016). In the group of rosacea patients whose sera reacted to B. oleronius proteins, the level of sebum was statistically lower than in controls (P = 0.01). The density of D. folliculorum on the face of Bacillus positive rosacea patients was statistically higher than controls (P = 0.0001). Rosacea patients demonstrated increased Demodex populations on their faces and reduced sebum levels. Their sera also showed reactivity to B. oleronius proteins, suggesting a potential role for this bacterium in the aetiology of rosacea.

  9. Phenylketonuria: brain phenylalanine concentrations relate inversely to cerebral protein synthesis.

    Science.gov (United States)

    de Groot, Martijn J; Sijens, Paul E; Reijngoud, Dirk-Jan; Paans, Anne M; van Spronsen, Francjan J

    2015-02-01

    In phenylketonuria, elevated plasma phenylalanine concentrations may disturb blood-to-brain large neutral amino acid (LNAA) transport and cerebral protein synthesis (CPS). We investigated the associations between these processes, using data obtained by positron emission tomography with l-[1-(11)C]-tyrosine ((11)C-Tyr) as a tracer. Blood-to-brain transport of non-Phe LNAAs was modeled by the rate constant for (11)C-Tyr transport from arterial plasma to brain tissue (K1), while CPS was modeled by the rate constant for (11)C-Tyr incorporation into cerebral protein (k3). Brain phenylalanine concentrations were measured by magnetic resonance spectroscopy in three volumes of interest (VOIs): supraventricular brain tissue (VOI 1), ventricular brain tissue (VOI 2), and fluid-containing ventricular voxels (VOI 3). The associations between k3 and each predictor variable were analyzed by multiple linear regression. The rate constant k3 was inversely associated with brain phenylalanine concentrations in VOIs 2 and 3 (adjusted R(2)=0.826, F=19.936, P=0.021). Since brain phenylalanine concentrations in these VOIs highly correlated with each other, the specific associations of each predictor with k3 could not be determined. The associations between k3 and plasma phenylalanine concentration, K1, and brain phenylalanine concentrations in VOI 1 were nonsignificant. In conclusion, our study shows an inverse association between k3 and increased brain phenylalanine concentrations.

  10. CT detection of thyroid pyramidal lobe in preoperative patients with thyroid tumors

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Gi Won; Kim, Dong Won [Dept. of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of)

    2013-10-15

    Thyroid pyramidal lobe (TPL) is a normal variant of the thyroid gland, but few imaging studies of TPL have been published. The purpose of this study is to investigate the frequency, location, size (length, maximal AP diameter, maximal transverse diameter), and upper end level of TPL with its separation from the main thyroid gland on preoperative neck CT and to compare them with operative findings in order to assess the diagnostic accuracy of neck CT for detection TPL. 46 patients, who underwent preoperative neck CT before thyroidectomy, were included in the study. The frequency, location, size, and upper end level of TPL with its separation from the main thyroid gland on the neck CT was analyzed by a single radiologist. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of neck CT for detecting TPL was 77.8%, 89.5%, 91.3%, 73.9% and 82.6%. There was a significant difference in maximal AP diameter, location, upper end level, and its separation from main thyroid gland between CT and operative findings (p < 0.05), but there was no significant difference in the length and maximal transverse diameter of TPL (p > 0.05). Diagnostic accuracy of neck CT for detecting TPL was high, and the neck CT may be useful for evaluating TPL in the suprahyoid neck.

  11. Fourfold Increase in Pumpkin Yield in Response to Low-Dosage Root Zone Application of Urine-Enhanced Biochar to a Fertile Tropical Soil

    Directory of Open Access Journals (Sweden)

    Hans Peter Schmidt

    2015-09-01

    Full Text Available A widely abundant and invasive forest shrub, Eupatorium adenophorum, was pyrolyzed in a cost-efficient flame curtain kiln to produce biochar. The resulting biochar fulfilled all the requirements for premium quality, according to the European Biochar Certificate. The biochar was either applied alone or mixed with fresh cow urine (1:1 volume to test its capacity to serve as slow release fertilizer in a pumpkin field trial in Nepal. Treatments included cow-manure compost combined with (i urine-only; (ii biochar-only or (iii urine-loaded biochar. All materials were applied directly to the root zone at a biochar dry matter content of 750 kg·ha−1 before seeding. The urine-biochar treatment led to a pumpkin yield of 82.6 t·ha−1, an increase of more than 300% compared with the treatment where only urine was applied, and an 85% increase compared with the biochar-only treatment. This study showed for the first time that a low-dosage root zone application of urine-enhanced biochar led to substantial yield increases in a fertile silt loam soil. This was tentatively explained by the formation of organic coating of inner pore biochar surfaces by the urine impregnation, which improved the capacity of the biochar to capture and exchange plant nutrients.

  12. A RETROSPECTIVE STUDY OF ARYTENOID DISLOCATION AFTER ENDOTRACHEAL INTUBATION

    Institute of Scientific and Technical Information of China (English)

    郭向阳; 罗爱伦; 任洪智; 叶铁虎; 黄宇光

    1998-01-01

    Five cases of arytendid dislocation after intuhation under general anesthesia are reported in this article.The anatomical and anesthetic causes of this complication were studied restrospectively, and the methods of treatment were discussed. The result showed that the incidence of arytenoid dislocation was about 0. 09% (5/5 826). Hoarseness, dysphonia and difficulty in feeding were the prevalent symptoms, and poor mobility of the vceal fold was the most common sign. The treatment included closed reduction of the displaced arytenoid under local anesthesia, steroid and physical therapy. The possible causes of arytenold dislocation were summarized as follows, (1) trauma produced by the blade tip of laryngoscope, (2) the use of styler,(3) overstretching of aryepiglottic fold and vocal cord during laryngoscopy and intubation, and (4) coughing and movemaent of the endotracheal tube on the larynx during the endotracheal tuba in place. It was suggested that correct technique and gentle manipulation during intubation could reduce the incidence of the complication. Timely postoperative follow-up and early reduction of arytenold cartilage should be emphasized in the diagnosis and treatment of the complication.

  13. Residue analysis and dissipation of a new fungicide 2-allylphenol in tomato

    Institute of Scientific and Technical Information of China (English)

    HU Ji-ye; ZHANG Wen-ji; LI Jian-zhong

    2005-01-01

    The method of residue analysis of a new synthesized fungicide 2-allylphenol was studied by simulating the active compound structure in Gingko tree( Gingko biloba L. ) and its dissipation rate and terminal residue levels in tomato under field condition. Residues of 2-allylphenol were extracted from tomato matrix with acetone, purified by liquid-liquid extraction and Florisil cartrieges, and then determined by HPLC with UV-detector. The minimum detectable amount of 2-allylphenol was 3 × 10-9 g, the minimum detectable concentration of 2-allylphenol in the samples of tomato were 0.01 mg/kg. The ranges of average recoveries and coefficient variation of the method were 87.7%-90.2% and 1.25%-2.06%, respectively. The dissipation rate and terminal residue levels in tomato were determined with the method described above. The results showed that the half-life of 2-allylphenol in tomato was 6.37 d, and 2-allylphenol declined with 82.6 %of the initial deposit remaining in tomato at harvest. The terminal residue levels in tomato were 0.15 mg/kg and 0.20 mg/kg following the recommended doses and time intervals.

  14. Design of Shrouded Airborne Wind Turbine & CFD Analysis

    Science.gov (United States)

    Anbreen, Faiqa; Faiqa Anbreen Collaboration

    2015-11-01

    The focus is to design a shrouded airborne wind turbine, capable to generate 70 kW to propel a leisure boat. The idea of designing an airborne turbine is to take the advantage of different velocity layers in the atmosphere. The blades have been designed using NREL S826 airfoil, which has coefficient of lift CL of 1.4 at angle of attack, 6°. The value selected for CP is 0.8. The rotor diameter is 7.4 m. The balloon (shroud) has converging-diverging nozzle design, to increase the mass flow rate through the rotor. The ratio of inlet area to throat area, Ai/At is 1.31 and exit area to throat area, Ae/At is1.15. The Solidworks model has been analyzed numerically using CFD. The software used is StarCCM +. The Unsteady Reynolds Averaged Navier Stokes Simulation (URANS) K- ɛ model has been selected, to study the physical properties of the flow, with emphasis on the performance of the turbine. Stress analysis has been done using Nastran. From the simulations, the torque generated by the turbine is approximately 800N-m and angular velocity is 21 rad/s.

  15. Protective Efficacy of the Calicivirus Valency of the Leucofeligen Vaccine against a Virulent Heterologous Challenge in Kittens

    Directory of Open Access Journals (Sweden)

    Cynthia Lesbros

    2013-01-01

    Full Text Available Feline calicivirus (FCV is a common feline pathogen with a potential for antigenic diversity. This study aimed to evaluate and characterize the protective efficacy of the FCV-F9 valency of a tetravalent vaccine, Leucofeligen, against challenge with an unrelated strain. Ten 9-week-old kittens were vaccinated while 10 remained as unvaccinated controls. The vaccinated cats received Leucofeligen twice subcutaneously with a 3-week interval. Four weeks after the second vaccination, all cats were challenged with virulent heterologous FCV and followed up for 21 days, monitoring their general condition, clinical signs, and immunological responses. During the vaccination phase, rectal temperatures and body weights were indistinguishable between the two groups. Only vaccinated cats showed FCV-specific seroconversion (both total and neutralizing antibodies. In the first week after challenge, the vaccinated cats had an 82.6% reduction in median clinical score compared to controls. Leucofeligen was thus shown to provide a significant clinical protection to kittens challenged with heterologous virulent FCV. This protection was similar whether the cats had neutralizing antibody or not, indicating a key role for cellular immunity in the overall protection. This also suggests that previously reported seroneutralisation studies may underestimate the level of cross-protection against field strains obtained with this modified live FCV-F9 vaccine.

  16. 伴智力低下孤独症谱系障碍儿童智力特征分析%Analysis of intellectual structure in children with autism spectrum disorders combined with hypophrenia

    Institute of Scientific and Technical Information of China (English)

    章丽丽; 刘毅梅; 窦红波; 魏艳; 杨洁; 吴燕玲

    2016-01-01

    目的 探讨伴有智力低下孤独症谱系障碍(autism spectrum disorder,ASD)儿童智力结构特点.方法 采用修订的韦氏儿童智力量表-中国版(Wechsler intelligence scale for children-Chinese edition WISC-R),对37例伴有智力低下的孤独症谱系障碍儿童和与之在性别、年龄相匹配的40名单纯智力低下儿童进行测试.结果 ASD组和对照组的总智商(full intelligence quotient,FIQ)分别为(54.70±8.26)分、(54.60±7.17)分,差异无统计学意义(P>0.05).ASD组的言语商(verbal intelligence quotient,VIQ)和操作商(performance intelligence quotient,PIQ)分别为(54.70±8.26)分、(64.51±12.25)分,对照组为(56.70±8.02)分、(57.25±9.43)分,ASD组表现出更低的VIQ和更高的PIQ,组间比较差异有统计学意义(t=3.582,P<0.01;t=2.928,P<0.01);ASD组VIQ-PIQ差异有统计学意义(t=8.14,P<0.01),对照组VIQ-PIQ差异无统计学意义.所有分测验中以拼图、积木得分高,理解得分最低.FIQ、VIQ以及常识、算术、理解、排列分测验得分与孤独症行为量表(ABC)总分呈负相关(r=-0.36,P<0.05;r=-0.40,P<0.05;r=-0.41,P<0.05:r=-0.44,P<0.01;r=-0.44,P<0.01;r=-0.35,P<0.05).结论 伴有智力低下孤独症谱系障碍儿童有特殊的认知模式,可为制定干预策略提供参考.%Objective To explore the intellectual profile of children with autism spectrum disorders (ASD) combined with hypophrenia.Methods The study followed a matching design,37 children with ASD combined with hypophrenia and 40 with simply intelligence disability while paired based on gender and age were selected.The intellectual profile of the studied children was determined with the Wechsler intelligence scale for children-Chinese edition (WISC-R) scale.Results The full intelligence quotient (FIQ) of the ASD group and the control group were (54.70±8.26) and (54.60-±7.17),the differences were not statistically significant(P>0.05).Verbal intelligence quotient(VIQ) and

  17. NUTRIENT UTILIZATION IN BUFFALO BULLS FED CROP RESIDUE BASED RATIONS

    Directory of Open Access Journals (Sweden)

    S. VENKATESWARLU

    2013-03-01

    Full Text Available In 4 x 4 LSD, four graded Murrah buffalo bulls (6 yrs; 353 ± 8.26 kg were fed four iso-nitrogenous complete rations comprising of jowar stover (CR1, maize stover (CR2, red gram straw (CR3 and black gram straw (CR4 as roughage source and concentrate mixture in 60:40 proportion, to study the effect of feeding complete rations on nutrient utilization. The DM intake (kg/d was similar in all the groups. The digestibility coefficients of DM, OM, CP, EE, CF, NDF, ADF, Cellulose and Hemi-cellulose were significantly (P<0.01 higher in buffalo bulls fed CR2 while NFE digestibility was higher (P<0.05 in CR3 when compared to those fed other complete rations. All the animals were in positive N, Ca and P balances. Further, the % DCP and % TDN were significantly higher (P<0.01 in buffalo bulls fed CR2. It could be concluded that maize stover compared to other crop residues could be a superior roughage source for inclusion in complete rations for feeding buffalo bulls.

  18. Pesquisa do estreptococo do Grupo B em gestantes da Zona Leste de São Paulo

    Directory of Open Access Journals (Sweden)

    Juliana Mello Função

    2013-02-01

    Full Text Available O presente trabalho trata-se de estudo transversal e retrospectivo, realizado com trinta mulheres usuárias de uma Unidade Básica de Saúde (UBS da Zona Leste de São Paulo, por meio de entrevista e consulta de prontuários, com o objetivo de verificar como ocorre a pesquisa do estreptococo do grupo B em gestantes. As participantes da amostra realizaram pré-natais na UBS etiveram seus bebês no período de janeiro de 2009 a dezembro de 2010. Realizaram a cultura do EGB 23 mulheres (76,7% do total, 82,6% com resultados negativos e 17,4%, positivos; 43,5% delas realizaram o exame entre 35 e 37 semanas de gestação; 23,5% não realizaram o exame, a maior parte por ausência de solicitação. Foi possível verificar que ocorreram falhas no rastreamento do EGB durante o período selecionado.

  19. The association between adult drug abuse and childhood maltreatment in students attending seven universities in five countries in Latin America and one country in the Caribbean

    Directory of Open Access Journals (Sweden)

    Samantha Longman-Mills

    2015-01-01

    Full Text Available Este estudio busca identificar la relación entre el maltrato durante la infancia y el abuso de drogas entre estudiantes de siete Universidad en cinco países de Latin America y uno país del Caribe. Este es un estudio hecho en varios países utilizando un diseño de corte para colectar los datos del abuso de drogas y un levantamiento retrospectivo sobre el maltrato en la infancia. La muestra fue constituida de 2.283 estudiantes universitarios, de los cuales 82,6% informaran maltrato en la infancia, y 33,5% informaran ter niveles elevados de distress psicológicos. Los datos indicaran una relación significante (p<0.05 entre el maltrato en la infancia y el abuso de drogas en la vida adulta. A pesar de la técnica amuéstrale no permitir generalización para la población de estudiantes universitarios, el presente estudio identifico que la exposición al maltrato durante la infancia es un precursor potencial para el abuso de drogas durante la vida adulta. Por lo tanto, estrategias para reducir el consume de drogas entre las respectivas universidades poden mejorar su efectividad si incorporan políticas e intervenciones que llevan en consideración el aspecto del maltrato en la infancia.

  20. Building Extraction from High Resolution Space Images in High Density Residential Areas in the Great Cairo Region

    Directory of Open Access Journals (Sweden)

    Mohamed A. Sherief

    2011-04-01

    Full Text Available This study evaluates a methodology for using IKONOS stereo imagery to determine the height and position of buildings in dense residential areas. The method was tested on three selected sites in an area of 8.5 km long by 7 km wide and covered by two overlapping (97% overlap IKONOS images. The images were oriented using rational function models in addition to ground control points. Buildings were identified using an algorithm that utilized the Digital Surface Model (DSM extracted from the images in addition to the image spectral properties. A digital terrain model was used with the DSM created from the IKONOS stereo imagery to compute building heights. Positional accuracy and building heights were evaluated using corner coordinates extracted from topographic maps and surveyed building heights. The results showed that the average building detection percentage for the test area was 82.6% with an average missing factor of 0.16. When the image rational polynomial coefficients were used to build the image model, results showed a horizontal accuracy of 2.42 and 2.39 m Root Mean Square Error (RMSE for the easting and northing coordinates, respectively. When ground control points were used, the results improved to the sub-meter level. Differences between building heights extracted from the image model and the corresponding heights obtained through traditional ground surveying had a RMSE of 1.05 m.

  1. Painting or relief: The ideal icon in iconophile writing in Byzantium

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    Pentcheva Bissera V.

    2006-01-01

    Full Text Available This text is focused on the transformation of the definition of the icon in Byzantine image theory from an identification of graphe with painting in the writings of John of Damascus (ca. 675-754 to the equation of graphe with typos understood as the imprint of an intaglio on matter in the theory of Theodore Studies (759-826. The virtues of painting, therefore, are that its masters see their works admired and feel themselves to be almost like the Creator. Is it not true that painting is the mistress of all the arts or their principal ornament? If I am not mistaken, the architect took from the painter architrave's, capitals, bases, columns and pediments, and all other fine features of buildings. The stonemason, the sculptor, and all the workshops and crafts of artificers are guided by the rule and art of the painter. Indeed hardly any art, except the very meanest, can be found that does not somehow pertain to painting. So I would venture to assert that whatever beauty there is in things, it has been derived from painting.

  2. Longitudinal Changes in Liver Aminotransferases Predict Metabolic Syndrome in Chinese Patients with Nonviral Hepatitis

    Institute of Scientific and Technical Information of China (English)

    CHEN Qi Cai; XIAO Juan; ZHANG Peng Peng; CHEN Li Li; CHEN Xiao Xiao; WANG Shu Mei

    2016-01-01

    ObjectiveThis study exploredthe correlation of longitudinal changes in serumalanine aminotransferase (ALT) and aspartate aminotransferase (AST)levels with the incidence of metabolic syndrome (Mets)based on a dynamic health examination cohort. MethodsA Mets-free dynamic cohortinvolving 4541 participants who underwent at leastthree health examinations from 2006 to 2011 was included in the study. Mets was defined according to the Chinese Medical Association Diabetes Branch definitionthat included hypertension, obesity, hyperlipidemia, and hyperglycemia. Generalized estimating equation (GEE) model was used to analyze multivariate relative risk (RR) of repeated observations ofALT and AST in quartiles for Mets or its components according to gender. ResultsIn all, 826Mets cases were reported. Adjustmentof relevant parameters indicated that time-varyingchanges in ALT and ASTlevels were positively associated with the incidenceof Mets in a dose-response manner. Positive association between high ALT levels and fatty liver was much stronger than that between high AST levels and fatty liver, particularly in maleparticipants. These associations were consistently observed in the following subgroups: participants with ALT and ASTlevels of ConclusionThese results suggested that elevated serum ALT and AST levels wereearly biomarkers of Mets or its components.

  3. Changes in small glaciers of the Trans-Himalaya of Ladakh, India

    Science.gov (United States)

    Schmidt, S.; Nüsser, M.

    2012-04-01

    This study deals with changes in small blank-ice glaciers in the Trans-Himalayan Kang Yatze Massif, Ladakh, Northwest India, between 1969 and 2010. Due to the semi-arid conditions and comparatively high temperatures, glaciers in Ladakh are characterized by their high altitude positions above 5200 m above sea level, and their relatively small size (map the glaciers of the Kang Yatze Massif, Ladkah and Stok Range along the Indus Valley and to detect and analyze their changes over a time period of four decades using multi-temporal remote sensing data (CORONA, Spot, and Landsat). Additionally, these remote sensing results were validated by four field campaigns which were carried out between 2007 and 2011. Preliminary results show that in the Kang Yatze Massif, covering an area of about 1000 km2, the glaciated area decreased from 96.4 to 82.6 km2 by about 14 % (0.3 % per yr) between 1969 and 2010. The ice cover loss shows a high decadal variability with the maximum shrinkage between 1991 and 2002 (0.6 % per yr), followed by a lower decrease rate since then (0.2 % per yr). Due to the high variability of glacier change, with a general trend of decreasing glaciated area, and a few stable glaciers; it becomes obvious that any extrapolation, even on a regional scale, is problematic. Therefore, a consideration of the differing responses of various glacier types and glacier sizes, is of the utmost importance.

  4. Whole brain white matter changes revealed by multiple diffusion metrics in multiple sclerosis: A TBSS study

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yaou, E-mail: asiaeurope80@gmail.com [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Duan, Yunyun, E-mail: xiaoyun81.love@163.com [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); He, Yong, E-mail: yong.h.he@gmail.com [State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875 (China); Yu, Chunshui, E-mail: csyuster@gmail.com [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Wang, Jun, E-mail: jun_wang@bnu.edu.cn [State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875 (China); Huang, Jing, E-mail: sainthj@126.com [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Ye, Jing, E-mail: jingye.2007@yahoo.com.cn [Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Parizel, Paul M., E-mail: paul.parizel@ua.ac.be [Department of Radiology, Antwerp University Hospital and University of Antwerp, Wilrijkstraat 10, 2650 Edegem, 8 Belgium (Belgium); Li, Kuncheng, E-mail: kunchengli55@gmail.com [Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053 (China); Shu, Ni, E-mail: nshu55@gmail.com [State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875 (China)

    2012-10-15

    Objective: To investigate whole brain white matter changes in multiple sclerosis (MS) by multiple diffusion indices, we examined patients with diffusion tensor imaging and utilized tract-based spatial statistics (TBSS) method to analyze the data. Methods: Forty-one relapsing-remitting multiple sclerosis (RRMS) patients and 41 age- and gender-matched normal controls were included in this study. Diffusion weighted images were acquired by employing a single-shot echo planar imaging sequence on a 1.5 T MR scanner. Voxel-wise analyses of multiple diffusion metrics, including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD) were performed with TBSS. Results: The MS patients had significantly decreased FA (9.11%), increased MD (8.26%), AD (3.48%) and RD (13.17%) in their white matter skeletons compared with the controls. Through TBSS analyses, we found abnormal diffusion changes in widespread white matter regions in MS patients. Specifically, decreased FA, increased MD and increased RD were involved in whole-brain white matter, while several regions exhibited increased AD. Furthermore, white matter regions with significant correlations between the diffusion metrics and the clinical variables (the EDSS scores, disease durations and white matter lesion loads) in MS patients were identified. Conclusion: Widespread white matter abnormalities were observed in MS patients revealed by multiple diffusion metrics. The diffusion changes and correlations with clinical variables were mainly attributed to increased RD, implying the predominant role of RD in reflecting the subtle pathological changes in MS.

  5. Genetic structuring in a relictual population of screaming hairy armadillo (Chaetophractus vellerosus) in Argentina revealed by a set of novel microsatellite loci.

    Science.gov (United States)

    Nardelli, Maximiliano; Ibáñez, Ezequiel Alejandro; Dobler, Dara; Justy, Fabienne; Delsuc, Frédéric; Abba, Agustín Manuel; Cassini, Marcelo Hernán; Túnez, Juan Ignacio

    2016-08-01

    The screaming hairy armadillo (Chaetophractus vellerosus) is a mammal species containing disjunct and isolated populations. In order to assess the effect of habitat fragmentation and geographic isolation, we developed seven new microsatellite loci isolated from low-coverage genome shotgun sequencing data for this species. Among these loci, six microsatellites were found to be polymorphic with 8-26 alleles per locus detected across 69 samples analyzed from a relictual population of the species located in the northeast of the Buenos Aires Province (Argentina). Mean allelic richness and polymorphic information content were 15 and 0.75, with observed and expected heterozygosities ranging from 0.40 to 0.67 and 0.58 to 0.90, respectively. All loci showed departures from Hardy-Weinberg equilibrium. The analysis of population structure in this relictual population revealed three groups of individuals that are genetically differentiated. These newly developed microsatellites will constitute a very useful tool for the estimation of genetic diversity and structure, population dynamics, social structure, parentage and mating system in this little-studied armadillo species. Such genetic data will be particularly helpful for the development of conservation strategies for this isolated population and also for the endangered Bolivian populations previously recognized as a distinct species (Chaetophractus nationi). PMID:27406582

  6. A Precision Measurement of the Neutral Pion Lifetime via the Primakoff Effect

    Energy Technology Data Exchange (ETDEWEB)

    Clinton, Eric [Univ. of Massachusetts, Amherst, MA (United States)

    2007-09-01

    The neutral pion radiative width has been measured to 8.411 eV ± 1.8% + 1.13% - 1.70% (lifetime = 7.826 ± 0.14 + 0.088 - 0.133 x 10-17 s) utilizing the Primakoff effect and roughly 4.9 to 5.5 GeV photons at the Thomas Jefferson National Accelerator Facility in Newport News, VA. The Hall B Photon Tagger, the Hall B Pair Spectrometer, a state of the art Hybrid Calorimter enabled precision incident photon energy measurement, photon flux measurement, and neutral pion identification, respectively. With these and other hardware and software tools, elastic neutral pion yields were extracted from the data. A well developed and understood simulation calculated geometric and software cut efficiency curves. The simulation also provided photo-pion production response functions to fit the experimental cross sections and extract the Primakoff cross section and thus the neutral pion radiative width and lifetime. Future work includes improving understanding of the nuclear incoherent process and any other background sources of elastic neutral pions in this data.

  7. Transcatheter Arterial Embolization for Postpartum Hemorrhage with Disseminated Intravascular Coagulation: Outcome Assessment

    Energy Technology Data Exchange (ETDEWEB)

    An, Eun Jung; Kim, Young Hwan; Kwon, Bo Ra; Kim, See Hyung [Dept. of Radiology, Dongsan Medical Center, Keimyung University College of Medicine, Daegu (Korea, Republic of)

    2011-12-15

    We evaluated the efficacy and predictors of clinical outcome after transcatheter arterial embolization (TAE) for treatment of postpartum hemorrhage with disseminated intravascular coagulation (DIC). Of 127 patients who underwent TAE for postpartum hemorrhage, 46 progressed to DIC (group 1), 81 showed normal range hematological parameters (group 2). We retrospectively evaluated etiology, embolization methods and the efficacy of TAE for intergroup comparison Pearson Chi-Square test and logistic regression model. Overall TAE failed to control bleeding in 9 patients in spite of technical success. Lower bleeding control rate was found in group 2 (82.6%) relative to group 1 (98.8%, p = 0.001). And embolization methods were not statistically different between two groups no statistically significant predictors associated with failed hemostasis except the amount of transfusion in group 1. Although bleeding control rate is lower in postpartum hemorrhage with DIC than without DIC, we believe that TAE with correction of DIC is an effective method for postpartum hemorrhage with DIC.

  8. Using Nanoinformatics Methods for Automatically Identifying Relevant Nanotoxicology Entities from the Literature

    Directory of Open Access Journals (Sweden)

    Miguel García-Remesal

    2013-01-01

    Full Text Available Nanoinformatics is an emerging research field that uses informatics techniques to collect, process, store, and retrieve data, information, and knowledge on nanoparticles, nanomaterials, and nanodevices and their potential applications in health care. In this paper, we have focused on the solutions that nanoinformatics can provide to facilitate nanotoxicology research. For this, we have taken a computational approach to automatically recognize and extract nanotoxicology-related entities from the scientific literature. The desired entities belong to four different categories: nanoparticles, routes of exposure, toxic effects, and targets. The entity recognizer was trained using a corpus that we specifically created for this purpose and was validated by two nanomedicine/nanotoxicology experts. We evaluated the performance of our entity recognizer using 10-fold cross-validation. The precisions range from 87.6% (targets to 93.0% (routes of exposure, while recall values range from 82.6% (routes of exposure to 87.4% (toxic effects. These results prove the feasibility of using computational approaches to reliably perform different named entity recognition (NER-dependent tasks, such as for instance augmented reading or semantic searches. This research is a “proof of concept” that can be expanded to stimulate further developments that could assist researchers in managing data, information, and knowledge at the nanolevel, thus accelerating research in nanomedicine.

  9. Large-Scale Evaluation of Maize Germplasm for Low-Phosphorus Tolerance

    Science.gov (United States)

    Zhang, Hongwei; Xu, Ruineng; Xie, Chuanxiao; Huang, Changling; Liao, Hong; Xu, Yunbi; Wang, Jinxiang; Li, Wen-Xue

    2015-01-01

    Low-phosphorus (LP) stress is a global problem for maize production and has been exacerbated by breeding activities that have reduced the genetic diversity of maize. Although LP tolerance in maize has been previously evaluated, the evaluations were generally performed with only a small number of accessions or with samples collected from a limited area. In this research, 826 maize accessions (including 580 tropical/subtropical accessions and 246 temperate accessions) were evaluated for LP tolerance under field conditions in 2011 and 2012. Plant height (PH) and leaf number were measured at three growth stages. The normalized difference vegetation index (NDVI) and fresh ear weight (FEW) were also measured. Genetic correlation analysis revealed that FEW and NDVI were strongly correlated with PH, especially at later stages. LP-tolerant and -sensitive accessions were selected based on the relative trait values of all traits using principal component analysis, and all the 14 traits of the tolerant maize accessions showed less reduction than the sensitive accessions under LP conditions. LP tolerance was strongly correlated with agronomic performance under LP stress conditions, and both criteria could be used for genetic analysis and breeding of LP tolerance. Temperate accessions showed slightly better LP tolerance than tropical/subtropical ones, although more tolerant accessions were identified from tropical/subtropical accessions, which could be contributed by their larger sample size. This large-scale evaluation provides useful information, LP-tolerant germplasm resources and evaluation protocol for genetic analysis and developing maize varieties for LP tolerance. PMID:25938641

  10. Effects of bovine serum proteins in culture medium on post-warming survival of bovine blastocysts developed in vitro.

    Science.gov (United States)

    Ohboshi, S; Etoh, T; Sakamoto, K; Fujihara, N; Yoshida, T; Tomogane, H

    1997-04-15

    Experiments were conducted to investigate the factors affecting the survival of bovine blastocysts produced in vitro after cryopreservation by vitrification. Zygotes were obtained by in vitro maturation and fertilization of oocytes. Embryos used in this study were developed in vitro at Day 7 and 8 (Day 0 = insemination day) in modified synthetic oviduct fluid medium supplemented with calf serum or BSA. Embryos were cryopreserved in a two-step protocol consisting of exposure to 10% ethylene glycol for 5 min, followed by the original vitrification solution (designated as VS) consisting of 40% (v/v) ethylene glycol, 6% (w/v) polyethylene glycol and 0.5 M sucrose in phosphate-buffered saline for 1 min. After warming, embryos were cultured in modified TCM-199 for an in vitro survival assay. The highest survival rate was obtained from the warmed embryos developed at Day 7 in medium supplemented with BSA (82.6%), and there were significant differences between results with calf scrum and BSA treatment (42.4 and 70.7%, respectively; P < 0.01). However, there were no significant differences in the cell numbers of embryos among the treatments. These results suggest that the survival of embryos developed in medium with BSA is superior to that of embryos developed in medium containing calf serum, although the cell numbers of the embryos developed under both media were similar. PMID:16728072

  11. The risk of asthma in patients with ankylosing spondylitis: a population-based cohort study.

    Directory of Open Access Journals (Sweden)

    Te-Chun Shen

    Full Text Available The relationship between asthma and ankylosing spondylitis (AS is controversial. We examined the risk of asthma among AS patients in a nationwide population.We conducted a retrospective cohort study using data from the National Health Insurance (NHI system of Taiwan. The cohort included 5,974 patients newly diagnosed with AS from 2000 to 2010. The date of diagnosis was defined as the index date. A 4-fold of general population without AS was randomly selected frequency matched by age, gender and the index year. The occurrence and hazard ratio (HR of asthma were estimated by the end of 2011.The overall incidence of asthma was 1.74 folds greater in the AS cohort than in the non-AS cohort (8.26 versus 4.74 per 1000 person-years with a multivariable Cox method measured adjusted HR of 1.54 (95% confidence interval (CI, 1.34-1.76. The adjusted HR of asthma associated with AS was higher in women (1.59; 95% CI, 1.33-1.90, those aged 50-64 years (1.66; 95% CI, 1.31-2.09, or those without comorbidities (1.82; 95% CI, 1.54-2.13.Patients with AS are at a higher risk of developing asthma than the general population, regardless of gender and age. The pathophysiology needs further investigation.

  12. Acute encephalitis and encephalopathy associated with human parvovirus B19 infection in children.

    Science.gov (United States)

    Watanabe, Toru; Kawashima, Hideshi

    2015-11-01

    Reports of neurologic manifestations of human parvovirus B19 (B19) infection have been on the rise. Acute encephalitis and encephalopathy is the most common, accounting for 38.8% of total B19-associated neurological manifestations. To date, 34 children with B19 encephalitis and encephalopathy have been reported, which includes 21 encephalitis and 13 encephalopathy cases. Ten (29%) were immunocompromised and 17 (39%) had underlying diseases. Fever at the onset of disease and rash presented in 44.1% and 20.6% of patients, respectively. Neurological manifestations include alteration of consciousness occurred in all patients, seizures in 15 (44.1%) patients, and focal neurologic signs in 12 (35.3%) patients. Anemia and pleocytosis in cerebrospinal fluid (CSF) occurred in 56.3% and 48.1% of patients, respectively. Serum Anti-B19 IgM (82.6%) and CSF B19 DNA (90%) were positive in the majority of cases. Some patients were treated with intravenous immunoglobulins and/or steroids, although an accurate evaluation of the efficacy of these treatment modalities cannot be determined. Nineteen (57.6%) patients recovered completely, 11 (33.3%) patients had some neurological sequelae and 3 (8.8%) patients died. Although the precise pathogenesis underlying the development of B19 encephalitis and encephalopathy is unclear, direct B19 infection or NS1protein of B19 toxicity in the brain, and immune-mediated brain injuries have been proposed. PMID:26566485

  13. RELATIONSHIP AMONG PS2 PROTEIN EXPRESSION, ESTROGEN AND PROGESTERONE RECEPTOR STATUS, AND PROGNOSIS OF BREAST CANCER

    Institute of Scientific and Technical Information of China (English)

    LIU Jingxian; LI Jiyou; HE Luowen; ZHAO Yajuan

    1999-01-01

    Objective: To study the relationship between the expression of PS2 protein and Estrogen (ER) and Progesterone Receptor (PR) status and their prognotic value in breast cancer. Methods: Using the immunohistochemical method, PS2 protein expressions were detected in 105 cases with breast cancer. Results:The positive rate of PS2 protein was 50.48% (53/105) in 105 cases. The positive rate of PS2 in the patients who survived five years or more was 56.96% (45/79), which was higher than that of those who lived less than five years (30.77%, 8/26). In the ER, PR (+) patients, the positive rate of PS2 was higher (76.74%, 33/34), than that of those with ER, PR (-) (22.5%, 9/40). Conclusions:Our results suggest that the expression of PS2 protein was positively correlated with the S-year-survival and that of ER and PR in breast cancer. It is considered that PS2 may be as a prognostic predictor, and detection of PS2 protein expression was useful for a guiding treatment of breast cancer.

  14. Na(+) Micro-Current Value Detection as a New Modality for Identification of Benign and Malignant Disease in Surgery.

    Science.gov (United States)

    Zhang, Xu-Feng; Long, Zhi-Da; Liu, Xue-Min; Ma, Feng; Li, Qiang; Lv, Yi

    2016-01-01

    Increase of intracellular positive ions (mainly Na(+)) indicates greater possibility of cell malignancy. The present study investigated the correlation between the Na(+) micro-current value (MCV) and tissue characteristics (normal, benign or malignant). 346 tissue samples have been detected within 30 min after surgical isolation by Na(+) detector. MCV in 102 malignant tumor was significantly higher than that in benign/borderline tumor or normal tissue (33.3 ± 8.9 μA vs. 24.4 ± 8.6 μA and 14.0 ± 4.0 μA, p detector and pathological examination was different in tissues from different organs or systems, which was high in pancreas, bile duct system, gastrointestinal system, esophagus, breasts, lungs, nose &throat and thyroids, but poor in urinary tissue. The overall coincidence rate was 83.1% (108/130) between Na(+) detector and pathological examination. The sensitivity and specificity of correct diagnosis by Na(+) detector was 83.3% (70/84) and 82.6% (38/46), respectively. This new modality may have diagnostic potential in complementing frozen examination in differentiating malignant tumor from benign or normal tissue, justifying tumor metastatic scope and confirming surgical margin. PMID:27103487

  15. Genetic relatedness of genus Oryza from Eastern Himalayan region as revealed by chloroplast matK gene

    Directory of Open Access Journals (Sweden)

    Doris Zodinpuii

    2013-12-01

    Full Text Available Phylogenetic relationship was studied in wild and cultivated rice using the chloroplast matK gene. The aligned sequence fragments were 826bp in length with 7.02% variable and 4.47% phylogenetically informative sites and the estimated Transition/Transversion bias (R was 1.97. Seven hundred and two characters were constant, 74 variable characters were parsimony-uninformative and 50 were parsimony–informative. Haplotypes of Mizoram rice and wild relatives (A genome were more similar than those of distantly related species (B, C/CD, E and G genomes. It further revealed that the EE genome species is most closely related to the CC genome and CCDD genomes. The BBCC genome species had different origins, and their maternal parents had either the BB or CC genome. An additional genome type, HHKK was recognized in O. coarctata and O. schlechteri. Within the AA genome the African, O. glaberrima and O. longistaminatea and American, O. glumipatula and O. barthii were closer to the Indian Oryza species, O. nivara and O. rufipogon. The unknown genome O. malampuzhaensis from India is closer to BB and BBCC genome containing respectively O. punctata from Cameroon and O. minuta from Philippines. CpG rich matK sequences were rich in GG and FF genotypes, whereas CpA rich sequences belonged to BB and BBCC related genomes variety.

  16. Label-free fluorescence detection of melamine with a truncated aptamer.

    Science.gov (United States)

    Gu, Chunmei; Xiang, Yu; Guo, Hongli; Shi, Hanchang

    2016-07-21

    The 2008 Chinese milk scandal caused by the adulteration of melamine encouraged the public to pay attention to melamine detection in milk products and other food stuffs. To allow simple and rapid detection of melamine, we previously isolated an 88 nt melamine aptamer (called Rd29C33) using the structure-switching SELEX. However, this 88 nt oligonucleotide is costly to synthesize, and may also complicate the rational design of biosensors for melamine detection. To overcome this obstacle, we truncated Rd29C33 at several sites, and a 34 nt Rd29C33-T7 melamine aptamer was finally found to show comparable binding affinity and better selectivity to melamine compared to the original 88 nt Rd29C33. Furthermore, a label-free bioassay method for melamine detection was designed by using Rd29C33-T7 and thiazole orange (TO). The addition of melamine to a mixture of Rd29C33-T7 and TO caused the release of TO from Rd29C33-T7, resulting in a decrease of the fluorescence intensity of the solution. A detection limit of 0.12 μM for melamine was achieved using this label-free method. Good recovery ranging from 82.6% to 97.2% for melamine detection in whole milk samples suggested the promise of this bioassay method for application in monitoring melamine in real food stuffs. PMID:27171923

  17. Clinical features, epidemiology, and efficacy and safety of intralesional antimony treatment of cutaneous leishmaniasis: recent experience in Turkey.

    Science.gov (United States)

    Uzun, Soner; Durdu, Murat; Culha, Gulnaz; Allahverdiyev, Adil M; Memisoglu, Hamdi R

    2004-08-01

    A total of 1,030 patients, 40.2% men and 59.8% women, identified during the period of October 1998 to November 2002 as having cutaneous leishmaniasis (CL), were studied; 1,431 lesions were identified in the 1,030 patients. One lesion was present in 80.7% of the patients. The size of the lesions (longest axis) was 13.6 mm (standard, 12.1 mm; range 3-150 mm). Most of the lesions were of the papular type (51.2%), although several atypical clinical presentations of CL were observed. The duration of the disease ranged between 1 and 72 mo (mean duration, 10.8 mo). The clinical suspicion of CL was confirmed by the observation of amastigotes on lesion tissue samples stained by Giemsa. The test was positive in 851 of 1,030 patients (82.6%). Intralesional meglumine antimonate solution (85 mg Sb/ml, 0.2-1 ml, depending on the size of the lesion) weekly until complete cure or up to 20 wk was used for first-line therapy of 890 patients (86.4%). We found that this regimen of intralesional Sb has an efficacy of 97.2% with a low relapse rate of 3.9% and no serious adverse side effects. PMID:15357081

  18. Genetic Factors Are Not the Major Causes of Chronic Diseases.

    Science.gov (United States)

    Rappaport, Stephen M

    2016-01-01

    The risk of acquiring a chronic disease is influenced by a person's genetics (G) and exposures received during life (the 'exposome', E) plus their interactions (G×E). Yet, investigators use genome-wide association studies (GWAS) to characterize G while relying on self-reported information to classify E. If E and G×E dominate disease risks, this imbalance obscures important causal factors. To estimate proportions of disease risk attributable to G (plus shared exposures), published data from Western European monozygotic (MZ) twins were used to estimate population attributable fractions (PAFs) for 28 chronic diseases. Genetic PAFs ranged from 3.4% for leukemia to 48.6% for asthma with a median value of 18.5%. Cancers had the lowest PAFs (median = 8.26%) while neurological (median = 26.1%) and lung (median = 33.6%) diseases had the highest PAFs. These PAFs were then linked with Western European mortality statistics to estimate deaths attributable to G for heart disease and nine cancer types. Of 1.53 million Western European deaths in 2000, 0.25 million (16.4%) could be attributed to genetics plus shared exposures. Given the modest influences of G-related factors on the risks of chronic diseases in MZ twins, the disparity in coverage of G and E in etiological research is problematic. To discover causes of disease, GWAS should be complemented with exposome-wide association studies (EWAS) that profile chemicals in biospecimens from incident disease cases and matched controls. PMID:27105432

  19. Sonoclot coagulation analysis: a useful tool to predict mortality in overt disseminated intravascular coagulation.

    Science.gov (United States)

    Wan, Peng; Yu, Min; Qian, Min; Tong, Huasheng; Su, Lei

    2016-01-01

    Disseminated intravascular coagulation (DIC) contributes to high mortality. The study was performed to investigate Sonoclot as a potential predictor of 30-day survival in overt DIC. This cohort included 237 consecutive critically ill patients with overt DIC, admitted to a 15-bed multidisciplinary ICU between July 2010 and July 2013. Hemostasis was analyzed with Sonoclot, including activated clotting time (ACT), clot rate, and platelet function, as well as routine clotting test at admission to the critical care center. Sonoclot variables differed in survivors and nonsurvivors. Mean ACT was prolonged (289.9 ± 200.5 vs. 194.8 ± 126.6 s; P < 0.001) and platelet function (1.2 ± 0.9 vs. 1.6 ± 1.2; P = 0.010) was reduced in nonsurvivors. The clot rate was not different. Cox proportional-hazard model showed that ACT and platelet function correlated independently with survival (P < 0.05). Kaplan-Meier survival curve analysis suggested that patients with one pathological Sonoclot findings have better outcome (P < 0.05). After ACT and platelet function were introduced, the receiver-operating characteristic area under the curve of model achieved 0.876 (P < 0.05), with a specificity of 82.6% and a sensitivity of 80.5% in prediction of 30-day survival by multivariate analyses. Our data suggest that the Sonoclot can predict mortality in critically ill patients with overt DIC.

  20. CT detection of thyroid pyramidal lobe in preoperative patients with thyroid tumors

    International Nuclear Information System (INIS)

    Thyroid pyramidal lobe (TPL) is a normal variant of the thyroid gland, but few imaging studies of TPL have been published. The purpose of this study is to investigate the frequency, location, size (length, maximal AP diameter, maximal transverse diameter), and upper end level of TPL with its separation from the main thyroid gland on preoperative neck CT and to compare them with operative findings in order to assess the diagnostic accuracy of neck CT for detection TPL. 46 patients, who underwent preoperative neck CT before thyroidectomy, were included in the study. The frequency, location, size, and upper end level of TPL with its separation from the main thyroid gland on the neck CT was analyzed by a single radiologist. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of neck CT for detecting TPL was 77.8%, 89.5%, 91.3%, 73.9% and 82.6%. There was a significant difference in maximal AP diameter, location, upper end level, and its separation from main thyroid gland between CT and operative findings (p 0.05). Diagnostic accuracy of neck CT for detecting TPL was high, and the neck CT may be useful for evaluating TPL in the suprahyoid neck.

  1. Parameters of the CGCS 2000 Ellipsoid and Comparisons with GRS 80 and WGS 84

    Directory of Open Access Journals (Sweden)

    CHENG Pengfei

    2016-02-01

    Full Text Available According to the definition of China Geodetic Coordinate System 2000(CGCS 2000 and defined constants of the ellipsoid adopted by CGCS 2000,the other geometrical and physical parameters of this ellipsoid are derived and compared with that from GRS 80 and WGS 84,respectively.Meanwhile the coordinates and normal gravity on the CGCS 2000 ellipsoid are compared with that on WGS 84 and GRS 80.The difference between the normal gravity on CGCS 2000 ellipsoid and that on GRS 80 is about -143.54×10-8 m/s2,while it is 0.02×10-8 m/s2 compared to WGS 84.The longitudes of a point on these three ellipsoids are the same,but the maximum difference of latitude between CGCS 2000 and GRS 80 is 8.26×10-11 arc seconds,which is about 2.5×10-6 mm,and the maximum difference of latitude between CGCS 2000 and WGS 84 is 3.6×10-6 arc seconds,which is about 0.11 mm.

  2. Development and use of touch-screen audio computer-assisted self-interviewing in a study of American Indians.

    Science.gov (United States)

    Edwards, Sandra L; Slattery, Martha L; Murtaugh, Maureen A; Edwards, Roger L; Bryner, James; Pearson, Mindy; Rogers, Amy; Edwards, Alison M; Tom-Orme, Lillian

    2007-06-01

    This article describes the development and usability of an audio computer-assisted self-interviewing (ACASI) questionnaire created to collect dietary, physical activity, medical history, and other lifestyle data in a population of American Indians. Study participants were part of a cohort of American Indians living in the southwestern United States. Data were collected between March 2004 and July 2005. Information for evaluating questionnaire usability and acceptability was collected from three different sources: baseline study data, auxiliary background data, and a short questionnaire administered to a subset of study participants. For the subset of participants, 39.6% reported not having used a computer in the past year. The ACASI questionnaires were well accepted: 96.0% of the subset of participants reported finding them enjoyable to use, 97.2% reported that they were easy to use, and 82.6% preferred them for future questionnaires. A lower educational level and infrequent computer use in the past year were predictors of having usability trouble. These results indicate that the ACASI questionnaire is both an acceptable and a preferable mode of data collection in this population. PMID:17379618

  3. A 20-year study on 190 patients with primary hyperparathyroidism in a developing country: Turkey experience.

    Science.gov (United States)

    Usta, Arif; Alhan, Etem; Cinel, Akif; Türkyılmaz, Serdar; Erem, Cihangir

    2015-04-01

    The aim of this study was to present our 20-year experience regarding primary hyperparathyroidism (PHPT). PHPT patients who underwent parathyroidectomy in our clinic were reviewed retrospectively. There were 190 PHPT patients, of whom 137 were asymptomatic (72%). The mean serum calcium at the time of diagnosis was 11.9 ± 2.2 mg/dL. The mean parathyroid hormone (PTH) level was 467 ± 78 pg/mL. Ultrasonography (USG) identified all abnormal glands accurately (82.6%) and Technetium-99m sestamibi scintigraphy (MIBI) was used in 89.4% of the patients and magnetic resonance imaging (MRI) in 61%. The common use of USG and MIBI detected 92% of the lesions. Bilateral neck exploration (BNE) was performed in 12.2% of the patients and focused unilateral neck exploration (FUNE) in the remaining 87.8%. Surgical intervention was unsuccessful in 1 patient (0.5%). The conversion ratio from FUNE to BNE was 5.2%. The mean operation time and mean hospital stay decreased significantly in patients with FUNE. Pathologic examination revealed single adenoma in 93% of the patients. New imaging techniques result in the conversion of surgical treatments of PHPT. FUNE in parathyroidectomy performed by an experienced surgeon may provide successful treatment rates. PMID:25875546

  4. Sociodemographic and clinical profile of children with congenital heart disease assisted at a hospital institution

    Directory of Open Access Journals (Sweden)

    Mirna Albuquerque Frota

    2014-06-01

    Full Text Available Objective: To characterize the sociodemographic and clinical profile of children with congenital heart disease assisted at a hospital institution. Methods: A descriptive, crosssectional study conducted in the pediatric cardiology outpatient clinic of a hospital in Fortaleza, CE, Brazil, in the period from March to August 2012. It comprised a nonrandom convenience sample of 80 parents of children with heart disease aged 5 to 12 years. Information was obtained from primary data of medical records and through questionnaires covering the parent’s sociodemographic characteristics, family data and the children’s clinical aspects. Results: Regarding socioeconomic data, 77 (96.2% caregivers were female, 50 (62.5% were married or in a stable relationship, 39 (48.7% had 10-12 years of formal education, and 69 (82.6% reported a household income between 1 and 2 minimum wages. In the sample of children studied, 43 (53.8% were female. The median age of the children was 8.4 years, ranging from 5-13 years. As to the age at the heart disease diagnosis, 44 (55% occurred under the age of 6 months, regardless of the type of cardiopathy. It was detected that 19 (23.75% were related to the disease. Conclusion: Children’s caregivers were predominantly their mothers, with low income and satisfactory schooling. Early diagnosis was predominant, mainly among the children with cyanotic cardiopathy. doi:10.5020/18061230.2014.p239

  5. Mercury, pets' and hair: baseline survey of a priority environmental pollutant using a noninvasive matrix in man's best friend.

    Science.gov (United States)

    Sousa, Ana C A; Teixeira, Isa Sofia de Sá; Marques, Bruna; Vilhena, Hugo; Vieira, Lisete; Soares, Amadeu M V M; Nogueira, António J A; Lillebø, Ana I

    2013-11-01

    Pet cats and dogs have been successfully used as indicators of environmental pollution by a great variety of chemicals, including metals. However, information on mercury (a well know priority environmental pollutant) concentrations in household pets tissues and/or organs is scarce. Thus, in the present work we quantified total mercury (Hg(Total)) in blood and hair samples from twenty-six household dogs. The obtained results disclose relatively low levels of total mercury in the surveyed dogs, with values ranging from 0.16 to 12.38 ng g(-1) in blood; and from 24.16 to 826.30 ng g(-1) in hair. Mercury concentrations were independent of gender, age and diet type. A highly significant positive correlation was established between total mercury in blood and hair, validating the latter as a surrogate, non-invasive matrix for mercury exposure evaluation. Additionally, the obtained blood to hair ratio (200) is similar to the one described for humans reinforcing the suitability of dogs as sentinels. Overall, the determination of total mercury levels in dogs' hair samples proved to be a good screening method for the estimation of mercury burden in this species. We propose the quantification of Hg(Total) in hair as a screening method for sentinels like household pets to be performed in routine veterinary visits. PMID:24085603

  6. Distribution of the h-index in radiation oncology conforms to a variation of power law: implications for assessing academic productivity.

    Science.gov (United States)

    Quigley, Matthew R; Holliday, Emma B; Fuller, Clifton D; Choi, Mehee; Thomas, Charles R

    2012-06-01

    Leaders of academic institutions evaluate academic productivity when deciding to hire, promote, or award resources. This study examined the distribution of the h-index, an assessment of academic standing, among radiation oncologists. The authors collected h-indices for 826 US academic radiation oncologists from a commercial bibliographic database (SCOPUS, Elsevier B.V., NL). Then, logarithmic transformation was performed on h-indices and ranked h-indices, and results were compared to estimates of a power law distribution. The h-index frequency distribution conformed to both the log-linear variation of a power law (r (2) = .99) and the beta distribution with the same fitting exponents as previously described in a power law analysis of the productivity of neurosurgeons. Within radiation oncology, as in neurosurgery, there are exceedingly more faculty with an h-index of 1-2. The distribution fitting the same variation of a power law within two fields suggests applicability to other areas of academia.

  7. Chemical composition and metabolizable energy values of feedstuffs for broiler chickens

    Directory of Open Access Journals (Sweden)

    Eliane Aparecida da Silva

    2012-03-01

    Full Text Available The objective of this study was to estimate the values of apparent metabolizable energy and apparent metabolizable energy corrected for nitrogen balance and determine the chemical composition of the following feedstuffs: babassu meal, sunflower meal, corn gluten meal, babassu starch flour, meat and bones meal, beans, millet, cookies residue, pasta residue and bread-making residue. The traditional method of excreta collection was used with broilers in the period of 14 to 24 days of age, which were distributed in a completely randomized design with eleven treatments and six replicates of six birds each. Each feedstuff replaced the reference diet at levels of 30 or 40% depending on the type of feedstuff. Chicks were housed in cages fitted with trays to collect the excreta. The apparent metabolizable energy corrected for nitrogen balance (kcal/kg on the natural matter of feedstuffs were: babassu meal, 1,116; sunflower meal, 1,607; corn gluten meal, 3,826; babassu flour starch, 1,731; meat and bone flour, 2,524; common beans, 693; millet, 3,046; cookies residue, 3,351; pasta residue, 3,543 and bread-making residue, 3,494.

  8. Duck Production: Has a Potential to Reduce Poverty among Rural Households in Asian Communities – A Review

    Directory of Open Access Journals (Sweden)

    F. Adzitey

    2015-08-01

    Full Text Available Duck production plays an important part in the agricultural economy of many Asia countries. The continent alone accounts for 82.6% of the total duck meat produced worldwide. Not only is Asia involved in duck production but also duck meat, eggs and their products are relished and consumed by many Asians. In spite of this, intensive education to empower rural households to increase duck production is limited. In recent times, much emphasize is being laid on commercialization to increase production at the neglect of rural household production. Subsequently this can affect the income levels of many rural households in Asia countries with the potential and can take the advantage to engage in duck production should they have been given adequate training and education. Poverty alleviation among rural communities had involved a number of strategies including women empowerment, promotion of crop, poultry and livestock production, and various activities of governmental and non-governmental organizations geared towards community development. Considering the population, importance and prospects of duck production in Asia, this mini review discusses the potentials duck farming has in reducing poverty level among rural communities in Asia

  9. 老年痴呆患病率及危险因素调查%INVESTIGATION OF PREVALENCE OF ALZHEIMER AND ITS RISK FACTORS

    Institute of Scientific and Technical Information of China (English)

    樊清华; 郑建中

    2011-01-01

    [Objective] To investigate the prevalence of dementia and its risk factors in elderly population in the region. [Methods] Conducted a sample survey among 1 826 cases ≥ 60 years in the region, with MMSE scale in the early screening, then the clinicians diagnosed the dementia according to the U.S. Diagnostic and Statistical Manual of Mental Disorders (4th edition). [Results] 64 cases in 1 826 cases of elderly patients were diagnosed with dementia, the prevalence was 3.5%; of which 42 cases of female patients, 22 cases of male patients, the incidence of female patients was significantly higher than male patients (2.3% VS 1.2%), there was a significant difference (P < 0.01); the number of cases aged ≥ 75 years and age < 75 years diagnosed with dementia were 46 patients, 18 patients, the incidence rate was 2.5%, 1.0% (P<0.01); the number of stroke patients and non-stroke patients diagnosed with dementia were 42 cases, 22 cases, the incidence rate was 2.3%, 1.2% (P < 0.01); and the number of cases with educational level below junior middle school or higher diagnosed with dementia were 38 cases, 26 cases, incidence rates were 2.1%, 1.4% (P< 0.01). The prevalence rates of Alzheimer's disease, vascular dementia and other dementia were 2.1%, 1.0% and 0.4%. [Conclusion] Alzheimer's disease is the main types of dementia in the region, female, age, history of stroke and level of education for older patients are common risk factors of dementia.%[目的]抽样调查某地区老年人群痴呆患病情况及其危险因素.[方法]对某地区≥60岁人群1 826例进行抽样调查,用简易精神量表MMSE进行初筛查,再由临床医师根据美国精神障碍诊断和统计手册第4版的标准诊断痴呆.[结果]1 826例老年人共确诊痴呆患者64例,患病率为3.5%;其中女性患者42例,男性患者22例,女性患者发病率显著高于男性患者(2.3%VS 1.2%),二者比较差异有统计学意义(P<0.01);年龄≥75岁与年龄< 75

  10. Testing DNA barcodes in closely related species of Curcuma (Zingiberaceae) from Myanmar and China.

    Science.gov (United States)

    Chen, Juan; Zhao, Jietang; Erickson, David L; Xia, Nianhe; Kress, W John

    2015-03-01

    The genus Curcuma L. is commonly used as spices, medicines, dyes and ornamentals. Owing to its economic significance and lack of clear-cut morphological differences between species, this genus is an ideal case for developing DNA barcodes. In this study, four chloroplast DNA regions (matK, rbcL, trnH-psbA and trnL-F) and one nuclear region (ITS2) were generated for 44 Curcuma species and five species from closely related genera, represented by 96 samples. PCR amplification success rate, intra- and inter-specific genetic distance variation and the correct identification percentage were taken into account to assess candidate barcode regions. PCR and sequence success rate were high in matK (89.7%), rbcL (100%), trnH-psbA (100%), trnL-F (95.7%) and ITS2 (82.6%) regions. The results further showed that four candidate chloroplast barcoding regions (matK, rbcL, trnH-psbA and trnL-F) yield no barcode gaps, indicating that the genus Curcuma represents a challenging group for DNA barcoding. The ITS2 region presented large interspecific variation and provided the highest correct identification rates (46.7%) based on BLASTClust method among the five regions. However, the ITS2 only provided 7.9% based on NJ tree method. An increase in discriminatory power needs the development of more variable markers.

  11. The prevalence of Blastocystis hominis and other protozoan parasites in soldiers returning from peacekeeping missions.

    Science.gov (United States)

    Duda, Aleksandra; Kosik-Bogacka, Danuta; Lanocha-Arendarczyk, Natalia; Kołodziejczyk, Lidia; Lanocha, Aleksandra

    2015-04-01

    Blastocystis hominis is a common intestinal parasite found in humans living in poor sanitary conditions, living in tropical and subtropical climates, exposed to infected animals, or consuming contaminated food or water. The aim of this study was to determine the prevalence of B. hominis in Polish military personnel returning from peacekeeping missions in Iraq and Afghanistan. In total, 1,826 stool samples were examined. Gastrointestinal parasites were detected in 17% of the soldiers. The examined stool samples most frequently contained vacuolar forms of B. hominis (15.3%) and cysts of Entamoeba coli (1.0%) or Giardia lamblia (0.7%). In 97.1% of stool samples from infected soldiers, we observed less than five developmental forms of B. hominis in the field of view (40×). The parasite infections in soldiers were diagnosed in the autumn and the spring. There was no statistical correlation between age and B. hominis infection. Our results show that peacekeeping missions in countries with tropical or subtropical climates could be associated with risk for parasitic diseases, including blastocystosis. PMID:25732683

  12. Treponemal infection and the outcome of pregnancy in a rural area of The Gambia, west Africa.

    Science.gov (United States)

    Greenwood, A M; D'Alessandro, U; Sisay, F; Greenwood, B M

    1992-10-01

    Of 826 pregnant women studied in a rural area of The Gambia, 77 (9.3%) were seropositive for a treponemal infection (positive rapid plasma reagin [RPR] and Treponema pallidum hemagglutination [TPHA] test). The perinatal death rate recorded prospectively in babies of 77 seropositive women (39.0/1000 births) was less than that among babies of 720 seronegative women (77.6/1000 births; odds ratio, 0.48; 95% confidence interval, 0.15-1.57). No increase in mortality or morbidity was found among the children of 39 seropositive women compared with the children of 39 control women. Seropositivity was found in only 20 (1.1%) of 1872 children less than 14 years old residing in the same community. The finding that the babies of rural Gambian women seropositive for syphilis are not at risk of early death is of importance in determining the priority that should be given to establishing antenatal screening programs in The Gambia and neighboring communities. PMID:1527421

  13. Energetic characterization of the husk of the castor bean fruits of the variety Guarani

    Energy Technology Data Exchange (ETDEWEB)

    Teramoto, Erico Tadao; Sousa, Frederico Faula; Castro Neto, Pedro [Universidade Federal de Lavras (DEG/UFLA), MG (Brazil). Dept. de Engenharia; Trugilho, Paulo Fernando [Universidade Federal de Lavras (DCF/UFLA), MG (Brazil). Dept. de Ciencias Florestais; Fraga, Antonio Carlos [Universidade Federal de Lavras (DAG/UFLA), MG (Brazil). Dept. de Agricultura; Nunes, Ramon Rachide [Universidade Federal de Lavras (DAG/UFLA), MG (Brazil). Dept. de Quimica

    2008-07-01

    The knowledge of the physical properties and of the calorific power and of the immediate chemical analysis certain products are interesting for the development of new technologies and equipment for your processing or use as fuel. This way, due to the scarce readiness of referring works for the husk of the castor bean fruits, the present study seeks complemental the available data in the literature. For such were certain the following properties of the husk of the castor bean fruits of variety Guarani: angle of repose, hectolitre weigh, moisture, ash content, volatile material content, fixed carbon content and superior calorific power and inferior calorific power. The following values were found: 42 deg for the angle of repose, 13.92 kg for the hectolitre weight, 4223.19 kcal/kg for the superior calorific power, 3829.92 kcal/kg for the inferior calorific power, 8.21% for the moisture, 9.86% for the ash content, 73.67% for the volatile material content and 8.26% for the fixed carbon content. (author)

  14. Identification of Ramie Genes in Response to Pratylenchus coffeae Infection Challenge by Digital Gene Expression Analysis

    Directory of Open Access Journals (Sweden)

    Yongting Yu

    2015-09-01

    Full Text Available Root lesion disease, caused by Pratylenchus coffeae, seriously impairs the growth and yield of ramie, an important natural fiber crop. The ramie defense mechanism against P. coffeae infection is poorly understood, which hinders efforts to improve resistance via breeding programs. In this study, the transcriptome of the resistant ramie cultivar Qingdaye was characterized using Illumina sequence technology. About 46.3 million clean pair end (PE reads were generated and assembled into 40,826 unigenes with a mean length of 830 bp. Digital gene expression (DGE analysis was performed on both the control roots (CK and P. coffeae-challenged roots (CH, and the differentially expressed genes (DEGs were identified. Approximately 10.16 and 8.07 million cDNA reads in the CK and CH cDNA libraries were sequenced, respectively. A total of 137 genes exhibited different transcript abundances between the two libraries. Among them, the expressions of 117 and 20 DEGs were up- and down-regulated in P. coffeae-challenged ramie, respectively. The expression patterns of 15 candidate genes determined by qRT-PCR confirmed the results of DGE analysis. Time-course expression profiles of eight defense-related genes in susceptible and resistant ramie cultivars were different after P. coffeae inoculation. The differential expression of protease inhibitors, pathogenesis-related proteins (PRs, and transcription factors in resistant and susceptible ramie during P. coffeae infection indicated that cystatin likely plays an important role in nematode resistance.

  15. Impacted Mandibular Third Molars: Review of Literature and a Proposal of a Combined Clinical and Radiological Classification.

    Science.gov (United States)

    Santosh, P

    2015-01-01

    Tooth impaction is a pathological situation where a tooth fails to attain its normal functional position. Impacted third molars are commonly encountered in routine dental practice. The impaction rate is higher for third molars when compared with other teeth. The mandibular third molar impaction is said to be due to the inadequate space between the distal of the second mandibular molar and the anterior border of the ascending ramus of the mandible. Impacted teeth may remain asymptomatic or may be associated with various pathologies such as caries, pericoronitis, cysts, tumors, and also root resorption of the adjacent tooth. Even though various classifications exist in the literature, none of those address the combined clinical and radiologic assessment of the impacted third molar. Literature search using the advanced features of various databases such as PubMed, Scopus, Embase, Google Scholar, Directory of Open Access Journals and Cochrane electronic databases was carried out. Keywords like impaction, mandibular third molar, impacted mandibular third molar, complications, anatomy, inferior alveolar nerve injury, lingual nerve injury were used to search the databases. A total of 826 articles were screened, and 50 articles were included in the review which was obtained from 1980 to February 2015. In the present paper, the authors have proposed a classification based on clinical and radiological assessment of the impacted mandibular third molar. PMID:26229709

  16. KEEFEKTIFAN INKUIRI TERBIMBING BERORIENTASI GREEN CHEMISTRY TERHADAP KETERAMPILAN PROSES SAINS

    Directory of Open Access Journals (Sweden)

    Nur Amalia Afiyanti

    2015-11-01

    Full Text Available This research aims to know the effectiveness of guided inquiry oriented green chemistry for science process skills at XI school grade of SMA in Semarang on 2012/2013 period. The population is normal and homogeneous, so to take two groups of samples using cluster random sampling techniques. Design of this research is posttest only control design. The succes of this research seen from cognitive aspect of student achievement reach KKM. At the final stage of the analysis, the t test used was left-test with t count > t table (1.696. The student achievement for experimental classes obtained t count of 3.860 while the control class 0,914. This suggests that the experimental class has achieved mastery learning, while the control class not yet. The average value of the psychomotor aspects of students in the experimental class was 82.6 which is included in the excellent category and control class was 74 included in good category. In the aspect of Students environmental concern, the average value of the experimental class was 88.65 included in the excellent category and class control was 81.7 included in good category. The conclusion was that the research-oriented guided inquiry of green chemistry proved effectively increase the science process skills.Keywords: Green Chemistry, Guided Inquiry, Science Process Skills

  17. Influence of radiochemotherapy on the nutritional status of patients with advanced carcinoma of the head and neck and presentation of a new method for imaging oral mucositis (digital dermascope system)

    International Nuclear Information System (INIS)

    The maintenance of nutritional status is a serious problem for patients suffering from head and neck cancer. Malnutrition leads to prolongation of hospitalisation and is an important risk factor in the development of postoperative complications and infections. This study was conducted to evaluate the consequences of radiochemotherapy on the nutritional status. Furthermore the timing for initiation of nutritional support was analysed. 23 patients with advanced carcinoma of the head and neck were studied prospectively. The treatment protocol consisted of conventional radiotherapy combined with infusional 5-fluorouracil and mitomycin-C. Anthropological, biochemical and immunological parameters and the Hackl-score were used to define malnutrition. The WHO-criteria and the digital dermascope-system were used for scoring and imaging oral mucositis. The dermascope-camera-system allows diagnosis of early mucosal changes and provides objective information on the patients' oral health. At the time of diagnosis malnutrition was present in some patients. Generally the nutritional status worsened until the beginning of therapy. After three weeks of treatment moderate or severe malnutrition and immunsuppression occurred in most of the patients. Analysis of the Hackl-score revealed an absolute indication for nutritional support in 82.6 %. At the end of treatment nutritional therapy was indicated in 100 % of the patients. Nutritional intervention was initiated too late in the clinical course. Prophylactic nutritional therapy is indicated when radiochemotherapy is planned for patients with advanced head and neck cancer.(author)

  18. Influence of radiochemotherapy on the nutritional status of patients with advanced carcinoma of the head and neck and presentation of a new method for imaging oral mucositis (digital dermascope system)

    International Nuclear Information System (INIS)

    The maintenance of nutritional status is a serious problem for patients suffering from head and neck cancer. Malnutrition leads to prolongation of hospitalization and is an important risk factor in the development of postoperative complications and infections. This study was conducted to evaluate the consequences of radiochemotherapy on the nutritional status. Furthermore the timing for initiation of nutritional support was analyzed. 23 patients with advanced carcinoma of the head and neck were studied prospectively. The treatment protocol consisted of conventional radiotherapy combined with infusional 5-fluorouracil and mitomycin-C. Anthropological, biochemical and immunological parameters and the Hackl-score were used to define malnutrition. The WHO-criteria and the digital dermascope-system were used for scoring and imaging oral mucositis. The dermascope-camera-system allows diagnosis of early mucosal changes and provides objective information on the patients' oral health. At the time of diagnosis malnutrition was present in some patients. Generally the nutritional status worsened until the beginning of therapy. After three weeks of treatment moderate or severe malnutrition and immunsuppression occurred in most of the patients. Analysis of the Hackl-score revealed an absolute indication for nutritional support in 82,6 %. At the end of treatment nutritional therapy was indicated in 100 % of the patients. Nutritional intervention was initiated too late in the clinical course. Prophylactic nutritional therapy is indicated when radiochemotherapy is planned for patients with advanced head and neck cancer. (author)

  19. Rituximab Treatment for Membranous Nephropathy: A French Clinical and Serological Retrospective Study of 28 Patients

    Directory of Open Access Journals (Sweden)

    Pierre-Antoine Michel

    2011-12-01

    Full Text Available The development of well-tolerated and effective therapies that target the pathogenesis of membranous nephropathy (MN would be useful. Our objective was to evaluate the efficacy of rituximab in MN. We analyzed the outcome of 28 patients treated with rituximab for idiopathic MN. Anti-PLA2R antibodies in serum and PLA2R antigen in kidney biopsy were assessed in 10 and 9 patients, respectively. Proteinuria was significantly decreased by 56, 62 and 87% at 3, 6 and 12 months, respectively. At 6 months, 2 patients achieved complete remission (CR and 12 partial remission (PR; overall renal response, 50%. At 12 months (n = 23, CR was achieved in 6 patients and PR in 13 patients (overall renal response, 82.6%. Three patients suffered a relapse of nephrotic proteinuria 27–50 months after treatment. Univariate analysis suggested that the degree of renal failure (MDRD estimated glomerular filtration rate 2 is an independent factor that predicts lack of response to rituximab. Anti-PLA2R antibodies were detected in the serum of 10 patients, and PLA2R antigen in immune deposits in 8 of 9 patients. Antibodies became negative in all 5 responsive patients with available follow-up sera. In this retrospective study, a high rate of remission was achieved 12 months after treatment.

  20. Spatial dynamics of carbon storage: a case study from Turkey.

    Science.gov (United States)

    Sivrikaya, Fatih; Baskent, Emin Zeki; Bozali, Nuri

    2013-11-01

    Forest ecosystems have an important role in carbon cycle at both regional and global scales as an important carbon sink. Forest degradation and land cover changes, caused by deforestation and conversion to non-forest area, have a strong impact on carbon storage. The carbon storage of forest biomass and its changes over time in the Hartlap planning unit of the southeastern part of Turkey have been estimated using the biomass expansion factor method based on field measurements of forests plots with forest inventory data between 1991 and 2002. The amount of carbon storage associated with land use and land cover changes were also analyzed. The results showed that the total forested area of the Hartlap planning unit slightly increased by 2.1%, from 27,978.7 ha to 28,282.6 ha during the 11-year period, and carbon storage increased by 9.6%, from 390,367.6 to 427,826.9 tons. Carbon storage of conifer and mixed forests accounted for about 70.6% of carbon storage in 1991, and 67.8% in 2002 which increased by 14,274.6 tons. Land use change and increasing forest area have a strong influence on increasing biomass and carbon storage. PMID:23771281

  1. Two new octahedral/pyramidal frameworks containing both cation channels and lone-pair channels: syntheses and structures of Ba2MnIIMn2III(SeO3)6 and PbFe2(SeO3)4

    International Nuclear Information System (INIS)

    The hydrothermal syntheses, single crystal structures, and some properties of Ba2MnIIMn2III(SeO3)6 and PbFe2(SeO3)4 are reported. These related phases contain three-dimensional frameworks of vertex (FeO6) and vertex/edge linked (MnO6) octahedra and SeO3 pyramids. In each case, the MO6/SeO3 framework encloses two types of 8 ring channels, one of which encapsulates the extra-framework cations and one of which provides space for the SeIV lone pairs. Crystal data: Ba2Mn3(SeO3)6, Mr=1201.22, monoclinic, P21/c (No. 14), a=5.4717 (3)A, b=9.0636 (4)A, c=17.6586 (9)A, β=94.519 (1)o, V=873.03 (8)A3, Z=2, R(F)=0.031, wR(F2)=0.070; PbFe2(SeO3)4, Mr=826.73, triclinic, P1-bar (No. 2), a=5.2318 (5)A, b=6.7925 (6)A, c=7.6445 (7)A, α=94.300 (2)o, β=90.613 (2)o, γ=95.224 (2)o, V=269.73 (4)A3, Z=1, R(F)=0.051, wR(F2)=0.131

  2. Reliability and validity of the Columbia Impairment Scale (C.I.S. for adolescents: Survey among an Italian sample in Lazio Region.

    Directory of Open Access Journals (Sweden)

    Alessandra Zanon

    2016-03-01

    Full Text Available Objective: Objective of this pilot study was to evaluate the reliability and internal consistency of the Columbia Impairment Scale questionnaire, as a tool to provide a global measure of impairment functioning in an Italian adolescents sample.Methods: The questionnaire is composed by 4 sections of functioning (interpersonal relations, broad psychopathological domains, functioning in schoolwork, use of leisure time for a total of 13 items. It was administered twice in the same sample belonging to a Professional School in Frosinone (Central Italy, to 120 adolescents on the first administration and to 108 on the second time. Reliability analysis was performed and Cronbach’s alpha was used as a measure of internal consistency. Statistical analysis was performed using SPSS 19.0.Results: Considering all 13 items, Cronbach’s alpha amounted to 0,762 on the first time and to 0.826 on the second time, showing a very satisfactory internal validity. In the sample selected, the answers to the questionnaire showed adolescents have a low impairment functioning.Conclusion: The results of the pilot study indicate that the questionnaire presents a good reliability property and in terms of internal consistency and validity shows a good performance. The results are promising and suggest that this tool cood be used in the Italian setting for future research targeted to adequately capture the impaired functioning in adolescents.

  3. PENINGKATAN PRODUKTIVITAS PADI SAWAH DENGAN INTRODUKSI VARIETAS UNGGUL BARU

    Directory of Open Access Journals (Sweden)

    KARSIDI PERMADI

    2012-11-01

    Full Text Available The increme of Wetland Rice Production with New High Yieldding Varieties The use of high yielding variety (HYV is one of the technology components that supports rice production, besides fertilizer and irrigation. Yet the use of HYV is still slowly adopted, resulting in continuing previous varieties application. The objectives of the research were to determine the HYV with the highest yield implementing integrated crop management (ICM. The location of research was in Tanjung Sari village, Pondok salam subdistrict, Purwakarta residence in 2009 dry season. The new seven HYVs (Inpari 1, Inpari 2, Inpari 3, Inpari 4, Inpari6, Inpara 2, and Aek Sibundong were treated with randomized complete block design (RCBD with four replications. The results showed that Aek Sibundong variety had the highest crop height, the number of panicle per hill, and the filled grain percentage. Aek Sibundong variety had 11.7 t/ha grain yield, while that Inpari 2 had 8.26 t/ha. There were significant correlation between dry yield and the number of panicle per hill and the number of grain per panicle, with the value of 4.470 and 0.479, respectively.

  4. Description of adsorption of hydrophobic organic compounds on sediment using multi-component adsorption model

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A chemical sequential separation procedure for sediment bas been developed for the adsorptive investigation of hydrophobic organic compounds(HOCs) including four fractions: carbonate, hydrous metallic oxide(ferric oxide, manganese oxide and alumina), clay and organic matter. Adsorption isotherms of these hydrophobic solute probes, such as hexachloroethane, lindane and 1,2,4,5-tetrachlorobenzene were measured for model sorbents, model and natural sediment, and the latter of which was pretreated with the simplified sequential separation method. The linear and Langmuir models are applied to correlate the experimental data of humic substance and other model sorbents respectively. Multi-component Adsorptive Model (MCAM) was used to simulate adsorption isotherms of model and natural sediment. The results reveal that( 1 ) the separation efficiencies of carbonate, organic matter, ferric oxide, manganese oxide and alumina are 98. 1 % , 72.5% ,82.6%, 93.5% and 83.3%, respectively; (2) except for removing metallic oxide, the external structure of sediment is not changed greatly after separation; (3) the MCAM correlates the data of adsorption isotherm rather well with the maximal relative deviations of 9.76 % , 6.78 %and 9.53% for hexachloroethane, lindane and 1,2,4,5-tetrachlorobenaze in model sediment, respectively. The MCAM can clearly give expression to the different adsorptive mechanisms for HOCs in organic and inorganic matter, though the experimental data in each component are not very accurate due to the sequential separation efficiency.

  5. External Validation of the Simple Clinical Score and the HOTEL Score, Two Scores for Predicting Short-Term Mortality after Admission to an Acute Medical Unit

    DEFF Research Database (Denmark)

    Stræde, Mia; Brabrand, Mikkel

    2014-01-01

    with the objective of validating the Simple Clinical Score (SCS) and the HOTEL score, two existing risk stratification systems that predict mortality for medical patients based solely on clinical information, but not only vital signs. METHODS: Pre-planned prospective observational cohort study. SETTING: Danish 460.......932 to 0.988) for 24-hours mortality and 0.826 (95% CI, 0.774-0.879) for 30-day mortality, and goodness-of-fit test, χ2 = 2.68 (10 degrees of freedom), P = 0.998 and χ2 = 4.00, P = 0.947, respectively. We included 1470 patients when calculating the HOTEL score. Discriminatory power (AUROC) was 0.931 (95......% CI, 0.901-0.962) for 24-hours mortality and goodness-of-fit test, χ2 = 5.56 (10 degrees of freedom), P = 0.234. CONCLUSION: We find that both the SCS and HOTEL scores showed an excellent to outstanding ability in identifying patients at high risk of dying with good or acceptable precision....

  6. Highly Luminescent Carbon Dots Synthesized by Microwave-Assisted Pyrolysis and Evaluation of Their Toxicity to Physa acuta.

    Science.gov (United States)

    Sun, Xiaobo; Jin, Xiaozhe; Pan, Wei; Guo, Enmian; Liu, Weijian; Li, Denghui; Lu, Kunchao; Si, Shuxin; Zhang, Nianxing; Jia, Zhenzhen; Shi, Yanping; Li, Qianqian; Wang, Jinping

    2016-01-01

    As a newly emerging class of nanomaterials, carbon dots have increasingly attracted researchers' attention. However, their potentially adverse environmental effects are yet largely unknown. In this work, the highly luminescent carbon dots were synthesized by microwave-assisted pyrolysis of tris(hydroxymethyl)aminomethane (Tris) and citric acid. Then acute and chronic toxicities of carbon dots to Physa acuta (P. acuta), as well as their effect on reproduction, were evaluated using the as-synthesized dots as an example. The quantum yield of the as-synthesized carbon dots was up to 53.5% excited at 360 nm with the most fluorescent fraction of 82.6% after simple purification by gel column. The results showed that no acute but chronic toxicities to P. acuta exposed to different treatment concentrations of the as-synthesized carbon dots were observed with dose- dependence. In addition, the fecundity of P. acuta was promoted significantly by the carbon dots at the concentrations of 0.5 and 1.0 mg/mL, yet inhibited at the concentration of 3.0 mg/mL after 12-day exposure. Mainly distributing in the visceral mass might be responsible for the effects of the carbon dots on the survival and fecundity of P. acuta. And there was no further evidence to confirm that the carbon dots can cause malformation in developing embryos.

  7. Initial mandate concerning the problem of fluctuating gasoline prices and their effect on the Quebec economy : Final report

    International Nuclear Information System (INIS)

    Over a three-year period covering May 1998 to May 2001, the average price of gasoline in Quebec slowly increased from 57.1 cent per litre to 82.6 cent per litre. This 45 per cent increase in the price of gasoline worried consumers and had an effect on commercial and industrial operations throughout the province. This situation prompted the Commission de l'economie et du travail (Commission on Labour and the Economy) to initiate a mandate to examine the problem. In October 2001, experts representing energy and taxation sectors were consulted and presentations made by 17 people and organizations. The Ministre des Ressources Naturelles (Minister of Natural Resources) and the President de la Regie de l'Energie were heard in a public consultation forum. In the first part of the document, the authors explained the mechanism by which the price of gasoline and its various components are determined, identified the elements responsible for the increases in prices, and compare the prices in the different parts of the province. In part two, the responsibilities and powers of the Ministry of Natural Resources and the Regie de l'Energie with regard to petroleum products were examined. Part three described the opinions expressed and proposed recommendations obtained during the public consultation process and they were grouped under four headings: taxation, competition, consumer information, and energy savings. The final part of the document presented the recommendations of the Commission on Labour and the Economy. 15 refs., 5 tabs

  8. PIUS-a: Problematic Internet Use Scale in adolescents. Development and psychometric validation.

    Science.gov (United States)

    Rial Boubeta, Antonio; Gómez Salgado, Patricia; Isorna Folgar, Manuel; Araujo Gallego, Manuel; Varela Mallou, Jesús

    2015-01-01

    Adolescents' use of the Internet is becoming a matter of great concern for different sectors of society. The psychological and behavioural consequences of problematic Internet use in young people demands quick and effective answers. One of the major challenges in this context is the development of empirically validated tools, which would facilitate early detection and screening for potential risk cases. This is precisely the aim of this paper. Based on a sample of 1,709 secondary-school students from Galicia (a region in northern Spain) aged 11 to 17 (M = 13.74, SD = 1.43), the analysis carried out permitted us to present a brief and simple tool (with just 11 items). It has substantial theoretical support, since both the existing background information and the views of experts from the academic and professional spheres were taken into account in the course of its development. The scale is adapted to the Spanish cultural context and to the language of young people. It has satisfactory psychometric properties in terms of reliability of the scores (α = .82), evidence of its internal structure (tested via a Confirmatory Factorial Analysis), sensitivity (81%), and specificity (82.6%). Moreover, its use enables the gradation of adolescents on a risk or problematic Internet use continuum. In our view, all of this lends it enormous applied potential in both the educational and clinical contexts. PMID:25879477

  9. 全科医学服务满意度问卷的信度分析%Reliability analysis on satisfaction on general physician's service

    Institute of Scientific and Technical Information of China (English)

    赖光强; 王跃平; 黄河清; 陈建; 周勇; 张炜

    2009-01-01

    目的:探讨全科医学服务满意度测量问卷的信度.方法:采用经"本地化"的全科医学服务满意度测量工作调查1765名患者,利用SPSS 13.0分别计算问卷的总Cronbach a系数和各因素的Cronbach a系数.结果:调查问卷的总Cronbach a系数为0.945,各因素的Cronbach a系数分别是医患沟通因素为0.793,技术服务因素为0.811,服务组织因素为0.826,均大于0.7,内部一致性信度较高.结论:全科医学服务满意度问卷具有较好的信度.

  10. Frequencies of virulence genes and pulse field gel electrophoresis fingerprints in Escherichia coli isolates from canine pyometra.

    Science.gov (United States)

    Maluta, Renato P; Borges, Clarissa A; Beraldo, Lívia G; Cardozo, Marita V; Voorwald, Fabiana A; Santana, André M; Rigobelo, Everlon C; Toniollo, Gilson H; Avila, Fernando A

    2014-11-01

    Escherichia coli is the most common bacterial agent isolated from canine pyometra. The frequencies of 24 virulence genes and pulsed field gel electrophoresis (PFGE) profiles were determined for 23 E. coli isolates from cases of canine pyometra in Brazil. The frequencies of virulence genes were 91.3% fimH, 91.3% irp-2, 82.6% fyuA, 56.5% iroN, 47.8% traT, 39.1% usp, 34.8% sfaD/E, 34.8% tsh, 30.4% papC, 30.4% hlyA, 26.1% papGIII, 26.1% cnf-1, 21.7% papE/F, 21.7% iss, 17.4% iutA, 17.4% ompT, 17.4% cvaC, 17.4% hlyF, 17.4% iucD, 13.0% iucC, 13.0% astA, 4.3% papGII, 0% afaB/C and 0% papGI. The high frequency of yersiniabactin (fyuA and irp2) and salmochelin (iroN) genes suggests that iron uptake systems might be important in the pathogenesis of canine pyometra. PFGE profiles of 19 isolates were heterogeneous, confirming that E. coli isolates from canine pyometra are unlikely to be epidemic clones. PMID:25201253

  11. EFEITO DA SUPLEMENTAÇÃO DE CAFEÍNA EM PARÂMETROS HEMATOLÓGICOS, IMUNOLÓGICOS E NO DESEMPENHO FÍSICO

    Directory of Open Access Journals (Sweden)

    João Rafael Valentim-Silva

    2014-02-01

    Full Text Available Therefore was objected to identify the effects of acute supplementation of caffeine with 8 and 16 mg.kg-1 in hematological and immunological parameters and the performance of the Wistar rats submitted in intense exercise until exhaustion. Materials and Methods: was selected 24 Wistar male rats, adults and sedentary with average weight of 174.86 + 8.26g and were randomly divided in control group (water CON (n=8, CAF8 (n=8 (8mg/kg e CAF16 (n=8 (16mg/kg administered the caffeine by gavage 30 minutes before the begin of experiment. The swimming happened in an aquarium with 60 cm of depth, water at 28°C, until the exhaustion with overload of 7.5% from their weight and immediately euthanized for the withdrawal of 1ml of their blood for lab analyzes. Results: 8 mg.kg-1 e 16 mg.kg-1 do not change the performance and the last do not change both parameters. The supplementation whit 8 mg.kg-1 of caffeine was able only increase the platelets count (p<0.05 and tended decrease the immunosuppressive tendency. Conclusions 8 mg.kg-1 of caffeine was able of increase the platelets account and decrease the immunosuppressive tendency of exhaustive exercise, but, do not shows be able in increase performance and 16mg/kg of caffeine do not change all investigated parameters.

  12. Gamma-ray spectrometry sensor and geochemical prospecting in an area of sugar cane plantation

    International Nuclear Information System (INIS)

    In this study the K, U and Th radionuclide concentrations were determined in a sugar cane plantation that received large quantities of fertilizer and gypsum. Geochemical data were obtained for the clay, iron and organic matter in the soil samples, taken from depths of 0-20 and 20-40 cm. The average radionuclide concentrations were 71 Bq Kg-1 for K; 5.97 Bq Kg-1 for U, and 11.26 Bq Kg-1 for Th, and the uranium was variable (56%). The radionuclide average concentrations for the different fertilizer compositions varied in the range of 603.5 - 8855.0 Bq Kg-1 for K; 27.3 - 684.4 Bq Kg-1 for U, and 58 - 788.5 Bq Kg-1 for Th, and it was most variable for K (53%). Gypsum average concentrations were 82.6 Bq Kg-1 for K, 641.5 Bq Kg-1 for U, and 201.7 Bq Kg-'1 for Th, and it was most variable for K (46%). Average organic matter, clay and iron concentrations for both the depths were 0.71 and 0.68 %; 16.2 and 16.9 %, and 29.0 and 26.8 mg/l respectively. (author)

  13. Analysis of Hydrologic Property of Poyang Lake%鄱阳湖水文特性分析

    Institute of Scientific and Technical Information of China (English)

    徐德龙; 熊明; 张晶

    2002-01-01

    The Poyang lake is currently the largest freshwater lake in China. Hydrologic properties of this lake, including precipitation, runoff, flood, sediment transport and so on have been analyzed on basis of large amount of measurements. Variation of these properties within a year and among years and the regional distribution are explored. The encounter probability of the outflow from Poyang Lake with that from Changjiang River is computed and the detention volume of Poyang Lake is analyzed. In accordance with water balance theory, the detention storage volume of Poyang Lake and Changjiang River corresponding to the annual maximum 60-day flood volumes in 9 typical heavy flood years of 1968, 1969, 1973, 1980, 1983, 1996 and 1998 have been calculated. The detention storage capacity of both the Lake and the River ranges from 5.6 billion to 16.5 billion m\\+3, 11.5 billion m\\+3 at average. Among which, the detention storage capacity of Poyang Lake is 9.5 billion m\\+3, accounting for 82.6%. Poyang Lake has played a very important role in detaining floods from the five rivers of the Lake system as well as floods on the river section from Changjiang to Bali. There would have more frequent and more serious flooding on the middle and lower Changjiang River, especially in the region around Hukou if there were no Poyang Lake to detain and store the floodwater.

  14. Enzyme activity and microorganisms diversity in soil contaminated with the Boreal 58 WG herbicide.

    Science.gov (United States)

    Kucharski, Jan; Tomkiel, Monika; Baćmaga, Małgorzata; Borowik, Agata; Wyszkowska, Jadwiga

    2016-07-01

    Next-generation herbicides are relatively safe when used properly, but the recommended rates are relatively low, which can lead to overdosing. This study evaluated the responses of soil-dwelling microorganisms and soil enzymes to contamination with the Boreal 58 WG herbicide. The analyzed product contains active ingredients flufenacet and isoxaflutole. All tests were performed under laboratory conditions. The analyzed material was sandy clay. Boreal 58 WG was introduced to soil in four doses. Soil without the addition of the herbicide served as the control. The soil was mixed with the tested herbicide, and its moisture content was maintained at 50% of capillary water capacity. Biochemical and microbiological analyses were performed on experimental days 0, 20, 40, 80 and 160. Accidental contamination of soil with the Boreal 58 WG herbicide led to a relatively minor imbalance in the soil microbiological and biochemical profile. The herbicide dose influenced dehydrogenase activity in only 0.84%, urease activity in 2.04%, β-glucosidase activity in 8.26%, catalase activity in 12.40%, arylsulfatase activity in 12.54%, acid phosphatase activity in 42.11%, numbers of organotrophic bacteria in 18.29%, actinomyces counts in 1.31% and fungi counts in 6.86%. PMID:27050595

  15. Isothermal dust models of Herschel-ATLAS galaxies

    CERN Document Server

    Smith, D J B; Jarvis, M J; Maddox, S J; Dunne, L; Bonfield, D G; Eales, S; Serjeant, S; Thompson, M A; Baes, M; Clements, D L; Cooray, A; De Zotti, G; Gonzàlez-Nuevo, J; van der Werf, P; Virdee, J; Bourne, N; Dariush, A; Hopwood, R; Ibar, E; Valiante, E

    2013-01-01

    We use galaxies from the Herschel-ATLAS survey, and a suite of ancillary simulations based on an isothermal dust model, to study our ability to determine the effective dust temperature, luminosity and emissivity index of 250um selected galaxies in the local Universe (z < 0.5). As well as simple far-infrared SED fitting of individual galaxies based on chi^2 minimisation, we attempt to derive the best global isothermal properties of 13,826 galaxies with reliable optical counterparts and spectroscopic redshifts. Using our simulations, we highlight the fact that applying traditional SED fitting techniques to noisy observational data in the Herschel Space Observatory bands introduces artificial anti-correlation between derived values of dust temperature and emissivity index. This is true even for galaxies with the most robust detections in our sample, making the results hard to interpret. We apply a method to determine the best-fit global values of isothermal effective temperature and emissivity index for z <...

  16. Tissues and hair residues and histopathology in wild rats (Rattus rattus L.) and Algerian mice (Mus spretus Lataste) from an abandoned mine area (Southeast Portugal)

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, R. [Departamento de Biologia da Universidade de Aveiro, Campus Universitario de Santiago, 3810-193 Aveiro (Portugal) and Instituto Piaget, Campus Academico de Viseu, Estrada do Alto do Gaio, Lordosa, 3515-776 Viseu (Portugal)]. E-mail: ruthp@bio.ua.pt; Pereira, M.L. [Departamento de Biologia da Universidade de Aveiro, Campus Universitario de Santiago, 3810-193 Aveiro (Portugal); Ribeiro, R. [Instituto do Ambiente e Vida, Departamento de Zoologia da Universidade de Coimbra, Largo Marques de Pombal, 3004-517 Coimbra (Portugal); Goncalves, F. [Departamento de Biologia da Universidade de Aveiro, Campus Universitario de Santiago, 3810-193 Aveiro (Portugal)

    2006-02-15

    Data gathered in this study suggested the exposure of rats and Algerian mice, living in an abandoned mining area, to a mixture of heavy metals. Although similar histopathological features were recorded in the liver and spleen of both species, the Algerian mouse has proved to be the strongest bioaccumulator species. Hair was considered to be a good biological material to monitor environmental contamination of Cr in rats. Significant positive associations were found between the levels of this element in hair/kidney (r = 0.826, n = 9, p < 0.01) and hair/liver (r = 0.697, n = 9, p = 0.037). Although no association was found between the levels of As recorded in the hair and in the organs, the levels of this element recorded in the hair, of both species, were significantly higher in animals captured in the mining area, which met the data from the organs analysed. Nevertheless, more studies will be needed to reduce uncertainty about cause-effect relationships. - The bioaccumulation of As and Cd and signs of renal histopathological injury proved the value of Algerian mice as a bioindicator species in the risk assessment of contaminated sites.

  17. Early and extraordinary peaks in physical performance come with a longevity cost.

    Science.gov (United States)

    van de Vijver, Paul L; van Bodegom, David; Westendorp, Rudi G J

    2016-08-01

    Life history theory postulates a trade-off between development and maintenance. This trade-off is observed when comparing life histories of different animal species. In humans, however, it is debated if variation in longevity is explained by differences in developmental traits. Observational studies found a trade-off between early and high fecundity and longevity in women. Development encompasses more than fecundity and also concerns growth and physical performance. Here, we show a life history trade-off between early and above average physical performance and longevity in male Olympic athletes. Athletes who peaked at an earlier age showed 17-percent increased mortality rates (95% CI 8-26% per SD, p≤0.001) and athletes who ranked higher showed 11-percent increased mortality rates (95% CI 1-22% per SD, p=0.025). Male athletes who had both an early and extraordinary peak performance suffered a 4.7-year longevity cost. (95% CI 2.1-7.5 years, p=0.001). This is the first time a life history trade-off between physical performance and longevity has been found in humans. This finding deepens our understanding of early developmental influences on the variation of longevity in humans. PMID:27540872

  18. Outcomes and satisfaction of patients with orthopaedic implants left in-situ for more than three years: a retrospective study

    Institute of Scientific and Technical Information of China (English)

    Aaran Heng-Chi Leung; Jeffrey Shen; Andraay Hon-Chi Leung; Yuk-Wah Hung; Anna HW Mok; Wing-Hoi Cheung; Kwok-Sui Leung

    2011-01-01

    Background There are no clear guidelines on implant removal. Few have assessed the long-term outcomes of patients with implants left in-situ, or removed. Therefore, removal of implants after fracture fixation remains controversial. Methods In this retrospective study, we reviewed 53 patients with implant for fracture fixation in-situ for more than 3 years. All patients were younger than 60 years. Quality of life of each patient was assessed with the Chinese (Hong Kong)validated Short Form-36 and the pain was assessed with visual analogue scale (VAS). All patients were clinically examined and plain radiographs were taken. Results The total SF-36 score of the patients was not statistically different from the Hong Kong norm (P >0.05). Mean score of VAS was 2.08. Thirty-three patients (62.3%) reported limited range of movement, 9 patients (17%) complained of cosmetic problems, and 10 patients (18.9%) complained of weakness. Clinically, 82.6% of patients had no scarring,84.7% of patients had full range of movement and all had no tenderness on assessment. Radiologically, no abnormality was detected except for one patient with known avascular necrosis of the femoral head after screw fixation. Conclusion As most patients were clinically and radiologically normal with quality of life scores comparable to the norm,removal of implants is not advisable as a routine practice.

  19. Effects of Assistant Solvents and Mixing Intensity on the Bromination Process of Butyl Rubber

    Institute of Scientific and Technical Information of China (English)

    王伟; 邹海魁; 初广文; 向阳; 彭晗; 陈建峰

    2014-01-01

    A slow bromination process of butyl rubber (IIR) suffers from low efficiency and low selectivity (S) of target-product. To obtain suitable approach to intensify the process, effects of assistant solvents and mixing inten-sity on the bromination process were systemically studied in this paper. The reaction process was found constantly accelerated with the increasing dosage and polarity of assistant solvent. Hexane with 30%(by volume) dichloro-methane was found as the suitable solvent component, where the stable conversion of 1,4-isoprene transferring to target product (xA1s) of 80.2%and the corresponding S of 91.2%were obtained in 5 min. The accelerated reaction process was demonstrated being remarkably affected by mixing intensity until the optimal stirring rate of 1100 r·min-1 in a stirred tank reactor. With better mixing condition, a further intensification of the process was achieved in a ro-tating packed bed (RPB) reactor, where xA1s of 82.6% and S of 91.9% were obtained in 2 min. The usage of the suitable solvent component and RPB has potential application in the industrial bromination process intensification.

  20. Characterization of bacterial pectinolytic strains involved in the water retting process.

    Science.gov (United States)

    Tamburini, Elena; León, Alicia Gordillo; Perito, Brunella; Mastromei, Giorgio

    2003-09-01

    Pectinolytic microorganisms involved in the water retting process were characterized. Cultivable mesophilic anaerobic and aerobic bacteria were isolated from unretted and water-retted material. A total of 104 anaerobic and 23 aerobic pectinolytic strains were identified. Polygalacturonase activity was measured in the supernatant of cell cultures; 24 anaerobic and nine aerobic isolates showed an enzymatic activity higher than the reference strains Clostridium felsineum and Bacillus subtilis respectively. We performed the first genotypic characterization of the retting microflora by a 16S amplified ribosomal DNA restriction analysis (ARDRA). Anaerobic isolates were divided into five different groups, and the aerobic isolates were clustered into three groups. 84.6% of the anaerobic and 82.6% of the aerobic isolates consisted of two main haplotypes. Partial 16S rRNA gene sequences were determined for 12 strains, representative of each haplotype. All anaerobic strains were assigned to the Clostridium genus, whereas the aerobic isolates were assigned to either the Bacillus or the Paenibacillus genus. Anaerobic isolates with high polygalacturonase (PG) activity belong to two clearly distinct phylogenetic clusters related to C. acetobutylicum-C. felsineum and C. saccharobutylicum species. Aerobic isolates with high PG activity belong to two clearly distinct phylogenetic clusters related to B. subtilisT and B. pumilusT. PMID:12919408

  1. Low Noise Figure and High Gain Single Stage Cascoded LNA Amplifier With Optimized Inductive Drain Feedback for WiMAX Application

    Directory of Open Access Journals (Sweden)

    Othman A.R

    2013-06-01

    Full Text Available This project presents a low noise and high gain cascoded LNA amplifier for direct conversion RF front end receiver architecture, which operates at 5.8 GHz unlicensed band. The LNA used Transistor FHX76LP superHEMT low noise FET. This LNA was designed and used inductive feedback and T- matching network consisting of lump reactive at the input and output of the LNA circuit. A single cascoded LNA design was built to meet the standard of IEEE 802.16. The cascoded LNA produced low noise figure of 0.83 dB with high gain of 26.26 dB. The S-parameter for the input reflection S11, output reflection S22, and return loss S12 are of -11.05 dB, -10.5 dB and -30.92 dB respectively. The bandwidth measured is 1.56 GHz, while the input sensitivity is -82.6 dBm which is compliant WiMAX standards. The single stage LNA amplifier simulated using Ansoft Designer SV.

  2. Association of the molecular regulation of ear leaf senescence/stress response and photosynthesis/metabolism with heterosis at the reproductive stage in maize

    Science.gov (United States)

    Song, Yi; Zhang, Zhe; Tan, Xianjie; Jiang, Yufeng; Gao, Jiong; Lin, Li; Wang, Zhenhua; Ren, Jun; Wang, Xiaolei; Qin, Lanqiu; Cheng, Weidong; Qi, Ji; Kuai, Benke

    2016-01-01

    Maize exhibits a wide range of heterotic traits, but the molecular basis of heterosis at the reproductive stage has seldom been exploited. Leaf senescence is a degenerative process which affects crop yield and quality. In this study, we observed significantly delayed ear leaf senescence in the reciprocal hybrids of B73/Mo17 and Zheng58/Chang7-2 after silking, and all the hybrids displayed larger leaf areas and higher stems with higher yields. Our time-course transcriptome analysis identified 2,826 differentially expressed genes (DEGs) between two parental lines (PP-DEGs) and 2,328 DEGs between parental lines and the hybrid (PH-DEGs) after silking. Notably, several senescence promoting genes (ZmNYE1, ZmORE1, ZmWRKY53 and ZmPIFs) exhibited underdominant expression patterns in the hybrid, whereas putative photosynthesis and carbon-fixation (ZmPEPC)-associated, starch biosynthetic (ZmAPS1, ZmAPL), gibberellin biosynthetic genes (ZmGA20OX, ZmGA3OX) expressed overdominantly. We also identified 86 transcription factors from PH-DEGs, some of which were known to regulate senescence, stress and metabolic processes. Collectively, we demonstrate a molecular association of the regulations of both ear leaf senescence/stress response and photosynthesis/metabolism with heterosis at the late developmental stage. This finding not only extends our understanding to the molecular basis of maize heterosis but also provides basic information for molecular breeding. PMID:27435114

  3. A Prospective Cohort Study on Radiation-induced Hypothyroidism: Development of an NTCP Model

    International Nuclear Information System (INIS)

    Purpose: To establish a multivariate normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism. Methods and Materials: The thyroid-stimulating hormone (TSH) level of 105 patients treated with (chemo-) radiation therapy for head-and-neck cancer was prospectively measured during a median follow-up of 2.5 years. Hypothyroidism was defined as elevated serum TSH with decreased or normal free thyroxin (T4). A multivariate logistic regression model with bootstrapping was used to determine the most important prognostic variables for radiation-induced hypothyroidism. Results: Thirty-five patients (33%) developed primary hypothyroidism within 2 years after radiation therapy. An NTCP model based on 2 variables, including the mean thyroid gland dose and the thyroid gland volume, was most predictive for radiation-induced hypothyroidism. NTCP values increased with higher mean thyroid gland dose (odds ratio [OR]: 1.064/Gy) and decreased with higher thyroid gland volume (OR: 0.826/cm3). Model performance was good with an area under the curve (AUC) of 0.85. Conclusions: This is the first prospective study resulting in an NTCP model for radiation-induced hypothyroidism. The probability of hypothyroidism rises with increasing dose to the thyroid gland, whereas it reduces with increasing thyroid gland volume.

  4. Shock Initiation of New and Aged PBX 9501 Measured with Embedded Electromagnetic Particle Velocity Gauges

    Energy Technology Data Exchange (ETDEWEB)

    L. G. Hill; R. L. Gustavsen; R. R. Alcon; S. A. Sheffield

    1999-09-01

    We have used an embedded electromagnetic particle velocity gauge technique to measure the shock initiation behavior in PBX 9501 explosive. Up to twelve separate particle velocity wave profile measurements have been made at different depths in a single experiment. These detail the growth from an input shock to a detonation. In addition, another gauge element called a ''shock tracker'' has been used to monitor the progress of the shock front as a function of time and position as it moves through the explosive sample. This provides data similar to that obtained in a traditional explosively driven wedge test and is used to determine the position and time that the wave attains detonation. Run distance-to-detonation vs. input pressure (Pop-plot) data and particle velocity wave profile data have been obtained on new PBX 9501 pressed to densities of 1.826, 1.830, and 1.837 g/cm{sup 3}. In addition, the same measurements were performed on aged material recovered from dismantled W76 and W78 weapons. The input pressure range covered was 3.0 to 5.2 GPa. All results to date show shock sensitivity to be a function only of the initial density and not of age. PBX 9501 shock initiates the same after 17 years in stockpile as it does on the day it is pressed. Particle velocity wave profiles show mixed heterogeneous initiation (growth in the front) and homogeneous initiation (growth behind the front).

  5. Evaluation of casing materials made from spent mushroom substrate and coconut fibre pith for use in production of Agaricus bisporus (Lange) Imbach

    Energy Technology Data Exchange (ETDEWEB)

    Pardo-Gimenez, A.; Pardo-Gonzalez, J. E.

    2008-07-01

    The agronomic performance of different proportions of mixtures of coconut fibre (CF) pith and spent mushroom substrate (SMS) was studied for their use as casing material in mushroom cultivation. After chemical and biological characterisation of the casing substrates qualitative and quantitative production parameters were evaluated in a cycle of Agaricus production. An increase in the proportion of SMS reduced the number of carpophores and overall yield; while the first flush was delayed, mushroom size tended to increase and the mushrooms had a higher dry matter content and a better texture, although their colour was worse. Combinations of CF pith and SMS of 4:1 and 3:2 (v/v) gave biological efficiencies of 92.9 and 82.6 kg 100 kg-1 compost, respectively. These values compare well with that obtained from the commercial casings used as a control. The high electrical conductivity of the mixture containing the highest proportion of SMS would limit its use. However, the results indicate the viability of reusing SMS as an ingredient of casing material for mushroom cultivation. This alternative could be considered to partially replace the organic substrates normally used for mushroom cultivation, with the double advantage of decreasing cost and reducing the environmental impact of waste disposal. Additional key words: alternative casing, compost reuse, mushroom cultivation. (Author) 31 refs.

  6. Flexible transparent conductive films combining flexographic printed silver grids with CNT coating

    Science.gov (United States)

    Mo, Lixin; Ran, Jun; Yang, Li; Fang, Yi; Zhai, Qingbin; Li, Luhai

    2016-02-01

    A high-performance ITO-free transparent conductive film (TCF) has been made by combining high resolution Ag grids with a carbon nanotube (CNT) coating. Ag grids printed with flexography have a 20 μm line width at a grid interval of 400 μm. The Ag grid/CNT hybrid film exhibits excellent overall performance, with a typical sheet resistance of 14.8 Ω/□ and 82.6% light transmittance at room temperature. This means a 23.98% reduction in sheet resistance and only 2.52% loss in transmittance compared to a pure Ag grid film. Analysis indicates that filling areas between the Ag grids and interconnecting the silver nanoparticles with the CNT coating are the primary reasons for the significantly improved conductivity of the hybrid film that also exhibits excellent flexibility and mechanical strength compared to an ITO film. The hybrid film may fully satisfy the requirements of different applications, e.g. use as the anode of polymer solar cells (PSCs). The J-V curve shows that the power conversion efficiency (PCE) of the PSCs using the Ag grid/CNT hybrid anode is 0.61%, which is 24.5% higher than that of the pure Ag grids with a PCE of 0.49%. Further investigations to improve the performance of the solar cells based on the printed hybrid TCFs are ongoing.

  7. Intradiscal Pressure Changes during Manual Cervical Distraction: A Cadaveric Study

    Directory of Open Access Journals (Sweden)

    M. R. Gudavalli

    2013-01-01

    Full Text Available The objective of this study was to measure intradiscal pressure (IDP changes in the lower cervical spine during a manual cervical distraction (MCD procedure. Incisions were made anteriorly, and pressure transducers were inserted into each nucleus at lower cervical discs. Four skilled doctors of chiropractic (DCs performed MCD procedure on nine specimens in prone position with contacts at C5 or at C6 vertebrae with the headpiece in different positions. IDP changes, traction forces, and manually applied posterior-to-anterior forces were analyzed using descriptive statistics. IDP decreases were observed during MCD procedure at all lower cervical levels C4-C5, C5-C6, and C6-C7. The mean IDP decreases were as high as 168.7 KPa. Mean traction forces were as high as 119.2 N. Posterior-to-anterior forces applied during manual traction were as high as 82.6 N. Intraclinician reliability for IDP decrease was high for all four DCs. While two DCs had high intraclinician reliability for applied traction force, the other two DCs demonstrated only moderate reliability. IDP decreases were greatest during moving flexion and traction. They were progressevely less pronouced with neutral traction, fixed flexion and traction, and generalized traction.

  8. Contraceptive Method Choice Among Newly Married Couples and Influential Factors in Shanghai Municipality

    Institute of Scientific and Technical Information of China (English)

    郭友宁; 方可娟; 施元莉; 楼超华; 林德良; 李惠沁; 张德玮

    1995-01-01

    A foliow-up study with 7,826 representative newly married couples for fifteen months after their weddings in Shanghai Municipality showed that among the 3,412 couples who actually adopted contraceptive method, rhythm was the main choice; the proportion for couples taking the contraceptive pill was much higher among sexually active couples before their weddings. The proportions of adopting rhythm or condom or the both, however, increased afterwards. About 86% of couples who had ever planned adopting the rhythm at registration actually used it. In fact, 16% of those who had ever planned to take pills eventually made this choice, because of their worry about any adverse side effects on mother's and fetus' health. Their knowledge about contraception, especially the pills, was incomprehensive. Approximately 62% of condom users had not been given any instruction regarding its use when they got this contraceptive device one year later. Half of the pill and spermicide users learnt these respective methods from their friends or relatives. The proportion of delivering contraceptives after marriage by F.P.P. was rather low. By fitting the multinomial logistic regression model, it is indicated that couple' s evaluation on contraceptive methods and contraceptive goal were the main factors determining newlyweds' method of choice. Wife's knowledge on contraception and the accessibility of contraceptives and devices also influenced the method choice to some extent.

  9. The Rotatory Displacement in the Spuracondylar Fracture of Extension Type in Children%小儿伸直型肱骨髁上骨折的旋转移位(诊断和治疗)

    Institute of Scientific and Technical Information of China (English)

    刘善雄

    1992-01-01

    介绍伸直型肱骨髁上骨折发生旋转移位的原因.根据肘部内上髁宽大,向内侧突出,外上髁小的解剖特点,结合骨折后正侧位X线片上所示骨突的长短、锐钝,骨折线的上下和重叠移位的部位,作为鉴别内旋或外旋移位临床诊断的依据.用来指导复位治疗.%Nineteen cases of supracondylar fracture of the humerus of extension type in children were treated from 1988 to 1989.All of the cases have a rotatory displacement.15 of 19 cases belong to the pronation type and other 4 the supination type.The mechanics of rotation was discussed.All patients were treated by manual reduction and short splint immobilization.13 of 19 cases were followed up for 8-26 raps.Elbow joint function Including extention,flexsion and forearm rotation was satisfactory.None had vascular or nervous complications.Follow up films of all 13 cases showed none with rotatory deformity in the distal fragment of the fracture,but 2 with cubitus varus.

  10. The Basic Life Support Training and Its Importance for Medical University Staff

    Directory of Open Access Journals (Sweden)

    Afrooz Habibi

    2015-06-01

    Full Text Available Background The survival rate of a cardiac arrest victim increases with basic life support (BLS as the first level of medical care. The purpose of this study was to compare BLS knowledge and skills of medical university staff before and after training course. Methods Thirty eight medical university staff participated in a BSL training course. The course included the assessment of participant’s knowledge by a pretest questionnaire, a lecture, hands-on training in BLS skills, a post-test questionnaire and an interview to evaluate their attitudes. Data were analyzed by the SPSS software version 19, using t-test, one-way ANOVA and chi square tests. P value less than 0.05 was considered statistically significant. Results Our results demonstrated that the mean knowledge score was 6.00 ± 2.09 vs. 8.26 ± 2.10 in pre- and post- education, respectively. A significant mean gain score (2.26 from the pre-test scores to post-test scores was statistically observed (P0.05 whereas, there were the significant differences between trainees’ gain scores and, education and career fields(p< 0.05. Our result also presents that staff attitudes toward the training were positive. Conclusion The present research shows the BLS training had a positive impact on the knowledge and attitudes among university staff. BLS training is extremely useful for medical university staf

  11. The Impact of Cardiac Diseases during Pregnancy on Severe Maternal Morbidity and Mortality in Brazil

    Science.gov (United States)

    Campanharo, Felipe F.; Cecatti, Jose G.; Haddad, Samira M.; Parpinelli, Mary A.; Born, Daniel; Costa, Maria L.; Mattar, Rosiane

    2015-01-01

    Background To evaluate maternal heart disease as a cause or complicating factor for severe morbidity in the setting of the Brazilian Network for Surveillance of Severe Maternal Morbidity. Methods and Findings Secondary data analysis of this multicenter cross-sectional study was implemented in 27 referral obstetric units in Brazil. From July 2009 to June 2010, a prospective surveillance was conducted among all delivery hospitalizations to identify cases of severe maternal morbidity (SMM), including Potentially Life-Threatening Conditions (PLTC) and Maternal Near Miss (MNM), using the new criteria established by the WHO. The variables studied included: sociodemographic characteristics, clinical and obstetric history of the women; perinatal outcome and the occurrence of maternal outcomes (PLTC, MNM, MD) between groups of cardiac and non-cardiac patients. Only heart conditions with hemodynamic impact characterizing severity of maternal morbidity were considered. 9555 women were included in the Network with severe pregnancy-related complications: 770 maternal near miss cases and 140 maternal death cases. A total of 293 (3.6%) cases were related to heart disease and the condition was known before pregnancy in 82.6% of cases. Maternal near miss occurred in 15% of cardiac disease patients (most due to clinical-surgical causes, pnear miss, among women presenting with any severe maternal morbidity. PMID:26650684

  12. 迷迭香单体的抗氧化活性%Antioxidation Activity of Monomer from Rosemary Antioxidant

    Institute of Scientific and Technical Information of China (English)

    毛绍春; 李竹英; 李聪

    2007-01-01

    采用柱层析方法对迷迭香抗氧化剂(Rao)进行分离,分离出8个含量较高的单体.用光度法、ESR法、滴定法测定了迷迭香的8个单体、单体组合及Rao的抗氧化活性,并分析了抗氧化活性与其结构的关系.结果表明,在单体中,对超氧阴离子自由基及羟基自由基清除率最高的是槲皮素,分别为82.6 %和87.1 %.对香烟烟气自由基平均清除率最高的是迷迭香二酚,清除率为48.17 %.单体活性最强的槲皮素和迷迭香二酚组合后,其抗氧化活性高于单体.活性强的抗氧化剂对油脂过氧化的抑制效果好,但作用时间较短.

  13. 伊立替康联合顺铂方案治疗复发性晚期小细胞肺癌23例临床观察%The clinical observation of combined chemotherapy of irinotecan and cisplatin in the treatment of relapsed advanced small cell lung cancer

    Institute of Scientific and Technical Information of China (English)

    Zhonghai Ren; Chenghui Zhang; Ming Li

    2008-01-01

    Objective:To evaluate the efficacy and safety of the irinotecan and cisplatin combination in relapsed advanced small cell lung cancer (SCLC).Methods:Eligible patients with SCLC who had progressed or relapsed after therapy were treated with cisplatin and irinotecan.The regimen consisted of irinotecan 60 mg/m2 on days 1,8,15 and cisplatin 60 mg/m2 on day 1;the plan was given every 28 days.Results:In 23 evaluable patients,responses included 5 complete remissions and 7 partial remissions (overall response rate,43.4%),6 patients had stable disease and 7 had progressive disease.Median time to progression and median survival were 4.6 and 8.3 months.The main toxicities were the hematologic toxicity,nausea and vomiting.Grade Ⅲ,Ⅳ leukopenia were seen in 15 patients (65.2%),thrombocytopenia was seen in 8 patients (34.8%);Nausea and vomiting were seen in 19 patients (82.6%);Grade Ⅲ,Ⅳ nausea and vomiting were seen in 4 patients (65.2%)and diarrhea was seen in 20 patients (87.0%).There were no treatment-related deaths.Conclusion:The combination of irinotecan and cisplatin is highly active and tolerable in patients with relapsed SCLC when it is administered as second-line treatment.

  14. Fifteen years of kidney biopsies in children: A single center in Egypt

    Directory of Open Access Journals (Sweden)

    Ashraf Bakr

    2014-01-01

    Full Text Available This study retrospectively investigates the indications and results of renal biopsy in children to determine the patterns of childhood kidney disease in a single tertiary children′s hospital in Egypt. We included all the patients who underwent ultrasound-guided renal biopsy from 1998 to 2012. All the kidney biopsies were studied under light microscopy, while immunofluorescence and electron microscopy were performed when indicated. A total of 1246 renal biopsies were performed over 15 years, on 1096 patients. The mean age of the patients at the time of biopsy was 9.2 ± 3.7 years. The main indication for a biopsy was the steroid-resistant nephrotic syndrome (n = 354, 28.4%, followed by the atypical nephrotic syndrome (n = 250, 20.1%, and renal abnormalities in the systemic diseases (n = 228, 18.3 %. In the 1226 pathologically diagnosed specimens, primary glomerulonephritis was the most common finding (n = 826, 67.4%, followed by secondary glomerulonephritis (n = 238, 19.4%. The most common causes of primary glomerulonephritis were Minimal Change Disease (MCD (n = 267, 21.8%, diffuse proliferative glomerulonephritis (n = 188, 15. 3%, and focal proliferative glomerulonephritis (n = 164, 13.3%. Lupus nephritis (n = 209, 17% was the most common cause of secondary glomerulonephritis. We conclude that the steroid-resistant nephrotic syndrome was the most frequent indication for biopsy and minimal change disease was the most common histopathological finding in our population.

  15. Late twentieth century land-cover change in the basin and range ecoregions of the United States

    Science.gov (United States)

    Soulard, Christopher E.; Sleeter, Benjamin M.

    2012-01-01

    As part of the US Geological Survey's Land Cover Trends project, land-use/land-cover change estimates between 1973 and 2000 are presented for the basin and range ecoregions, including Northern, Central, Mojave, and Sonoran. Landsat data were employed to estimate and characterize land-cover change from 1973, 1980, 1986, 1992, and 2000 using a post-classification comparison. Overall, spatial change was 2.5% (17,830 km2). Change increased steadily between 1973 and 1986 but decreased slightly between 1992 and 2000. The grassland/shrubland class, frequently used for livestock grazing, constituted the majority of the study area and had a net decrease from an estimated 83.8% (587,024 km2) in 1973 to 82.6% (578,242 km2) in 2000. The most common land-use/land-cover conversions across the basin and range ecoregions were indicative of the changes associated with natural, nonmechanical disturbances (i.e., fire), and grassland/shrubland loss to development, agriculture, and mining. This comprehensive look at contemporary land-use/land-cover change provides critical insight into how the deserts of the United States have changed and can be used to inform adaptive management practices of public lands.

  16. Exergaming as a viable therapeutic tool to improve static and dynamic balance among older adults and people with idiopathic Parkinson’s disease: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Dale Michael Harris

    2015-09-01

    Full Text Available The use of virtual reality games (known as ‘exergaming’ as a neurorehabilitation tool is gaining interest. Therefore, we aim to collate evidence for the effects of exergaming on the balance and postural control of older adults and people with idiopathic Parkinson’s disease (IPD. Six electronic databases were searched, from inception to April 2015, to identify relevant studies. Standardised mean differences (SMD and 95% confidence intervals (CI were used to calculate effect sizes between experimental and control groups. I2 statistics were used to determine levels of heterogeneity. 309 older adults and 74 people with IPD were assessed across eleven studies. The results showed that exergaming improved static balance (SMD 1.069, 95% CI 0.563 to 1.576, postural control (SMD 0.826, 95% CI 0.481 to 1.170 and dynamic balance (SMD -0.808, 95% CI -1.192 to -0.424 in healthy older adults. Two PD studies showed an improvement in static balance (SMD 0.124, 95% CI -0.581 to 0.828 and postural control (SMD 2.576, 95% CI 1.534 to 3.599. Our findings suggest that exergaming might be an appropriate therapeutic tool for improving balance and postural control in older adults, but more large-scale trials are needed to determine if the same is true for people with IPD.

  17. Prognostic factors in bone marrow transplantation for beta thalassemia major: experiences from Iran.

    Science.gov (United States)

    Ghavamzadeh, A; Nasseri, P; Eshraghian, M R; Jahani, M; Baybordi, I; Nateghi, J; Khodabandeh, A; Sadjadi, A R; Mohyeddin, M; Khademi, Y

    1998-12-01

    This study concerns the effects of several pre-transplant features on outcome for patients with beta thalassemia major who underwent bone marrow transplantation (BMT). Seventy patients with beta thalassemia major underwent bone marrow transplantation during the period 1991-1997 in Shariati Hospital in Tehran, Iran. The survival and rejection curves levelled off at 8 and 18 months after transplantation at 82.6% and 11.4%, respectively. Pre-transplant clinical features (age, serum ferritin, portal fibrosis, hepatomegaly and quality of chelation therapy) were examined for their effects on survival and recurrence of thalassemia in this group of patients who were less than 16 years old. Increasing age, presence of portal fibrosis and increasing serum ferritin were significantly associated with reduced probability of survival (P = 0.0047, P = 0.016 and P = 0.024, respectively). Hepatomegaly and inadequate pre-transplant chelation therapy which were documented as poor prognostic factors in previous studies, were not evaluable in this study. We also showed the benefits of transplanting more than 5.5 x 10(8)/kg cells in this group of patients with no increase in complications.

  18. Hydrogenated Amorphous Silicon Germanium Active Layer for Top Cell of a Multi Junction Cell Structure.

    Science.gov (United States)

    Cho, Jaehyun; Iftiquar, S M; Kim, Minbum; Park, Jinjoo; Jung, Junhee; Kim, Jiwoong; Yi, Junsin

    2016-05-01

    Intrinsic hydrogenated amorphous silicon-germanium (a-SiGe:H) alloy is generally used in the bottom cell because of its low band gap. The a-SiGe:H has a higher photo conductivity in comparison to the a-Si:H; thus, it is expected that the a-SiGe:H can show better short circuit current density than that of the a-Si:H based solar cell. Therefore, we optimized a-SiGe:H active layer that can be a suitable choice for the front cell of a multi junction.solar cell. Furthermore, we carried out a comparative study of the solar cells that have a-SiGe:H and a-Si:H as respective active layers. The a-SiGe:H based solar cells show higher short circuit current density, while the a-Si:H based cells show higheropen circuit voltage. The current-voltage characteristics of these cells are as follows: (a) V(oc) = 770 mV, J(sc) = 15.0 mA/cm2, FF = 64.5%, and η = 7.47% for a-SiGe:H based cell; and (b) V(oc) = 826 mV, J(sc) = 13.63 mA/cm2, FF = 72.0%, and η = 8.1% for a-Si:H based cell. PMID:27483837

  19. Use of homeopathy in organic dairy farming in Spain.

    Science.gov (United States)

    Orjales, Inmaculada; López-Alonso, Marta; Rodríguez-Bermúdez, Ruth; Rey-Crespo, Francisco; Villar, Ana; Miranda, Marta

    2016-02-01

    Organic farming principles promote the use of unconventional therapies as an alternative to chemical substances (which are limited by organic regulations), with homeopathy being the most extensive. Traditionally, Spain has had little faith in homeopathy but its use in organic farming is growing. Fifty-six Spanish organic dairy farmers were interviewed to obtain what we believe to be the first data on the use of homeopathy in organic dairy cattle in Spain. Only 32% of farms use some sort of alternative therapy (16.1% homeopathy, 10.7% phytotherapy and 5.3% using both therapies) and interestingly, a clear geographical pattern showing a higher use towards the East (similar to that in the human population) was observed. The main motivation to use homeopathy was the need to reduce chemical substances promoted by organic regulations, and the treatment of clinical mastitis being the principle reason. The number of total treatments was lower in farms using homeopathy compared with those applying allopathic therapies (0.13 and 0.54 treatments/cow/year respectively) and although the bulk SCC was significantly higher (p < 0.001) in these farms (161,826 and 111,218 cel/ml, respectively) it did not have any negative economical penalty for the farmer and milk quality was not affected complying with the required standards; on the contrary homeopathic therapies seems to be an alternative for reducing antibiotic treatments, allowing farmers to meet the organic farming principles. PMID:26828005

  20. Synthesis and Crystal Structure of Methyl 3-(5-Bromo-1-ethyl-1H-indole-3-carbonyl)aminopropionate

    Institute of Scientific and Technical Information of China (English)

    LI Kai-Ping; ZHENG Le; ZENG Xiang-Chao; HU Fang

    2011-01-01

    Methyl 3-(5-bromo-1-ethyl-1H-indole-3-carbonyl)aminopropionate has been syn-thesized by the acylation of 5-bromo-3-trichloroacetylindole with β-alanine methyl ester, followed by alkylation with ethyl iodide, in 82.6% yield. Its crystal structure was gotten and determined by Ⅹ-ray diffraction method. The crystal is of monoclinic, space group P2/c with a = 11.7927(8), b =14.9342(8), c=9.0060(5) A, β= 101.558(6)°, V= 1553.93(16) A,Z=4, Dc=1.510 g/cm,λ=0.71073 A,μ(MoKa) = 2.656 mm, Mr = 353.22 and F(000) = 720. The structure was refined to R =0.0401 and wR = 0.0825 for 1704 observed reflections with Ⅰ > 20(Ⅰ). In the crystal structure,intermolecular N(2)-H(2)…O(1) hydrogen bond and weak intermolecular bonds (C(1)-H(1)…O(1)and C(10)-H(10B)…O(2)) are formed, and π-π stacking also exists.

  1. Genetic variation of Garra rufa fish in Kermanshah and Bushehr provinces, Iran, using SSR microsatellite markers

    Directory of Open Access Journals (Sweden)

    Ali Shabani

    2013-09-01

    Full Text Available Six highly variable microsatellite loci were used to investigate the genetic diversity and population structure of the Garra rufa in Kermanshah and Bushehr provinces, Iran. All of the 6 microsatellite loci screened in this study showed polymorphism. A total of 90 individual fish from 3 populations were genotyped and 60 alleles were observed in all loci. The number of alleles per locus ranged from 6 to14. The average allelic number of these polymorphic markers was 10. The averages of observed (Ho and expected heterozygosity (He was 0.529 and 0.826, respectively. The genetic distance values ranged between 0.235-0.570. The UPGMA dendrogram based on genetic distance resulted in three clusters: Gamasiab population alone was classified as one and the other two populations as the second cluster. This study revealed a fairly high level of genetic variation in the microsatellite loci within the three populations, and identified distinct population groups of Garra rufa. This study gains significance for the analysis of the populations’ genetic diversity as well as the management of this important fish resource.

  2. Changes in Peripheral Hemodynamics and Clinical Symptoms in Patients With Arterial Hypertension and Abdominal Obesity Under the Influence of Treatment, Depending on Genes’ Polymorphism

    Directory of Open Access Journals (Sweden)

    Alina Sokolenko

    2015-03-01

    Full Text Available In 110 patients with essential arterial hypertension (EAH and overweight or abdominal obesity (AO analyzed changes of peripheral hemodynamics and clinical signs under the influence of treatment, depending on genes’ polymorphism of the Angiotensin-converting enzyme (ACE, I/D and the Peroxisome proliferator-activated receptor gamma-2 (PPAR-2, Pro12Ala. Under the combined treatment the "target" office blood pressure (BP was achieved in 72.8 % subjects, the "adequate" reduction of BP – in 82.6 % patients. Depending on the EAH severity: "target" BP achieved in 100% patients with EAH I stage vs 76.2 % in person with EAH II stage (p=0.019 and 53.1 % – with EAH III stage (p=0.002. "Target" average daily BP24, daily BPd and nighttime BPn were achieved in 70.0 % patients (prevail those with EAH I-II stages by 47.1 % and 21.2 % (p=0.049, respectively, in I-allele carriers of ACE gene – by 17,9% (p=0.048 and Ala-allele carriers of PPAR-2 gene by 38.9 % (p=0.036.

  3. Bioartificial heart: a human-sized porcine model--the way ahead.

    Directory of Open Access Journals (Sweden)

    Alexander Weymann

    Full Text Available BACKGROUND: A bioartificial heart is a theoretical alternative to transplantation or mechanical left ventricular support. Native hearts decellularized with preserved architecture and vasculature may provide an acellular tissue platform for organ regeneration. We sought to develop a tissue-engineered whole-heart neoscaffold in human-sized porcine hearts. METHODS: We decellularized porcine hearts (n = 10 by coronary perfusion with ionic detergents in a modified Langendorff circuit. We confirmed decellularization by histology, transmission electron microscopy and fluorescence microscopy, quantified residual DNA by spectrophotometry, and evaluated biomechanical stability with ex-vivo left-ventricular pressure/volume studies, all compared to controls. We then mounted the decellularized porcine hearts in a bioreactor and reseeded them with murine neonatal cardiac cells and human umbilical cord derived endothelial cells (HUVEC under simulated physiological conditions. RESULTS: Decellularized hearts lacked intracellular components but retained specific collagen fibers, proteoglycan, elastin and mechanical integrity; quantitative DNA analysis demonstrated a significant reduction of DNA compared to controls (82.6±3.2 ng DNA/mg tissue vs. 473.2±13.4 ng DNA/mg tissue, p<0.05. Recellularized porcine whole-heart neoscaffolds demonstrated re-endothelialization of coronary vasculature and measurable intrinsic myocardial electrical activity at 10 days, with perfused organ culture maintained for up to 3 weeks. CONCLUSIONS: Human-sized decellularized porcine hearts provide a promising tissue-engineering platform that may lead to future clinical strategies in the treatment of heart failure.

  4. Multifactors analysis of functional anorexy for children%学龄前儿童功能性厌食的多因素分析

    Institute of Scientific and Technical Information of China (English)

    韦萍

    2010-01-01

    [目的]分析影响儿童功能性厌食的因素,为预防儿童功能性厌食提供理论支持. [方法]选取在广西 壮族自治区妇幼保健院门诊就诊的儿童178例,其中功能性厌食儿童40例,用儿童调查问卷对儿童家长进行年龄、性别、病理性黄疸史、母乳喂养时间、辅食添加时间、户外运动、喂养方式及睡眠障碍等方面的调查,并以这些因素进行多因素的Logistic回归分析. [结果]喂养方式(Wald值=2.700,P=0.01,OR=3.156)和睡眠障碍(Wald值=2.905,P=0.035,OR=8.826)两因素均有统计学意义,其中睡眠障碍对儿童功能性厌食影响最大. [结论]睡眠障碍和喂养方式是影响儿童功能性厌食的重要因素.

  5. A new BODIPY/nanoparticle/Ni affinity system for binding of cytochrome c

    Energy Technology Data Exchange (ETDEWEB)

    Maltas, Esra, E-mail: maltasesra@gmail.com [Selcuk University, Faculty of Science, Department of Chemistry, 42075 Konya (Turkey); Selcuk University, Faculty of Science, Department of Biochemistry, 42075 Konya (Turkey); Kursunlu, Ahmed Nuri [Selcuk University, Faculty of Science, Department of Chemistry, 42075 Konya (Turkey); Arslan, Gulsin [Selcuk University, Faculty of Science, Department of Biochemistry, 42075 Konya (Turkey); Selcuk University, Advanced Research Technology and Application Center, 42075 Konya (Turkey); Ozmen, Mustafa [Selcuk University, Faculty of Science, Department of Chemistry, 42075 Konya (Turkey); Selcuk University, Advanced Research Technology and Application Center, 42075 Konya (Turkey)

    2015-09-15

    Highlights: • BODIPY was synthesized, and then attached to magnetic nanoparticles. • Ni(II) ions were chelated on prepared material. • The binding of cytochrome c to obtained material was studied. - Abstract: In this study, 3,5-{Bis[4,4-difluoro, 8-(2,6-diethyl, 1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene)]}benzoylchloride (BODIPY) was synthesized for the improving of a new immobilized metal affinity supporting material. Firstly, the synthesized BODIPY was immobilized on iron oxide superparamagnetic nanoparticles (SPIONs) and then, Ni(II) ions were chelated with the active terminals of BODIPY on nanoparticles surfaces to prepare an immobilized metal affinity (IMA) adsorbent for protein adsorption. The amount of BODIPY coated on SPIONs was about 29.7 μM at 10 mg nanoparticles. 738 μmol of Ni(II) ions were loaded to 10 mg of the SPIONs/BODIPY. The binding amount of cytochrome c was found to be 170 μg to the SPIONs/BODIPY/Ni at pH 7.4. The binding amount of the molecules on SPIONs was analyzed by using UV–vis, fluorescence and atomic absorption spectroscopy. The characterization of the prepared surfaces was performed by FT-IR, SEM and TEM.

  6. Academic Stress Influences Periodontal Health Condition and Interleukin-1 beta Level

    Directory of Open Access Journals (Sweden)

    Sandra O. Kuswandani

    2014-10-01

    Full Text Available Stress is a risk factor for periodontal disease, causing increase levels of interleukin-1 beta that involve in periodontal destruction. Objective: To analyze the relationship between academic stress in residency program students conditions and levels of interleukin-1 beta in gingival crevicular fluid. Methods: Thirty eight subjects filled the questionnaire of Graduate Dental Environtmental Stress (GDES, periodontal examination and samples of gingival crevicular fluid were tested for interleukin-1 beta with the Enzyme-linked Immunosorbent Assay (ELISA test. Results: There were significant differences between academic stress to periodontal tissue in oral hygiene (p=0.038, bleeding on probing index (p=0.02, but no significant differences in pocket depth and loss of attachment (p=0.972. There were significant differences between academic stress to levels of interleukin-1 beta (p=0.03, but no significant differences between levels of interleukin-1 beta to periodontal tissue in oral hygiene (p=0.465, bleeding on probing index (p=0.826, pocket depth (p=0.968, and loss of attachment (p=0.968. Conclusion: Academic stress influences the periodontal risk factor and level of interleukin-1 beta.

  7. Functional characterization of two low-density lipoprotein receptor gene mutations in two Chinese patients with familial hypercholesterolemia.

    Directory of Open Access Journals (Sweden)

    Haihong Wang

    Full Text Available Familial hypercholesterolemia (FH is an autosomal dominant disease that primarily results from mutations in the low-density lipoprotein receptor (LDLR gene. We investigated two unrelated Chinese FH patients using gene screening and functional analysis to reveal the pathogenicity and the mechanism by which these mutations cause FH.First, the LDLR gene was sequenced in these patients. Then, mutant receptors were transfected into human embryo kidney 293 (HEK-293 cells, and a confocal laser-scanning microscope was used to observe the localization of mutant proteins. Further, the expression and the internalization activity were analyzed by flow cytometry. Finally, LDLR protein expression and stability was detected by western blot.Two different LDLR class 2B mutations were detected in two patients. The C201F mutation is a known mutation. However, the G615V mutation is novel. Flow cytometry showed that the expression and internalization activity of the mutant LDLRs were reduced to 73.6% and 82.6% for G615V and 33.2% and 33.5% for C201F, respectively.This study identified two LDLR mutations in Chinese patients with FH and analyzed the relationship between the genotype and phenotype of these patients. We found that these mutant LDLRs were defective in transport, which led to a reduction in cholesterol clearance. These results increase our understanding of the mutational spectrum of FH in the Chinese population.

  8. Circulation of multiple serotypes of highly divergent enterovirus C in the Xinjiang Uighur Autonomous Region of China.

    Science.gov (United States)

    Zhang, Yong; Sun, Qiang; Cui, Hui; Yan, Dongmei; Fan, Qin; Song, Yang; Zhu, Shuangli; Li, Xiaolei; Huang, Guohong; Ji, Tianjiao; Hu, Lan; Wang, Dongyan; Yang, Qian; Xu, Wenbo

    2016-01-01

    Poliomyelitis associated with circulating vaccine-derived polioviruses (cVDPVs) is a serious public health issue in the post-eradication era, and the occurrence of recombinant cVDPVs emphasizes the need to elucidate enterovirus C (EV-C) epidemiology. Stool samples were collected from 826 healthy children in Southern Xinjiang in 2011 to investigate EV-C circulation and epidemiology. Thirty-six EV-Cs were isolated and assigned to eight EV-C serotypes by molecular serotyping, suggesting the circulation of diverse EV-Cs in Xinjiang. Phylogenetic analysis showed that the Xinjiang EV-C strains had larger variation compared to the prototype and other modern strains. Additionally, the results showed unique characteristics of Xinjiang EV-Cs, such as the cytopathicity of CV-A1 strains to RD cells; the high divergence in CV-A11, CV-A13, CV-A17, and CV-A20 strains; the divergence of Xinjiang CV-A24 from AHC-related CV-A24 variant stains distributed worldwide; and the circulation of two novel EV-C serotypes (EV-C96 and EV-C99). Evaluations of this dense and diverse EV-C ecosystem will help elucidate the processes shaping enteroviral biodiversity. This study will improve our understanding of the evolution of enteroviruses and the recombination potential between polioviruses and other EV-Cs. PMID:27642136

  9. Effects of Evapotranspiration on Mitigation of Urban Temperature by Vegetation and Urban Agriculture

    Institute of Scientific and Technical Information of China (English)

    QIU Guo-yu; LI Hong-yong; ZHANG Qing-tao; CHEN Wan; LIANG Xiao-jian; LI Xiang-ze

    2013-01-01

    The temperature difference between an urban space and surrounding non-urban space is called the urban heat island effect (UHI). Global terrestrial evapotranspiration (ET) can consume 1.4803×1023 joules (J) of energy annually, which is about 21.74%of the total available solar energy at the top of atmosphere, whereas annual human energy use is 4.935×1020 J, about 0.33%of annual ET energy consumption. Vegetation ET has great potential to reduce urban and global temperatures. Our literature review suggests that vegetation and urban agricultural ET can reduce urban temperatures by 0.5 to 4.0°C. Green roofs (including urban agriculture) and water bodies have also been shown to be effective ways of reducing urban temperatures. The cooling effects on the ambient temperature and the roof surface temperature can be 0.24-4.0°C and 0.8-60.0°C, respectively. The temperature of a water body (including urban aquaculture) can be lower than the temperature of the surrounding built environment by between 2 and 6°C, and a water body with a 16 m2 surface area can cool up to 2 826 m3 of nearby space by 1°C. Based on these findings, it can be concluded that the increase of evapotranspiration in cities, derived from vegetation, urban agriculture, and water body, can effectively mitigate the effect of urban heat islands.

  10. Development of nuclear technology for improving quality and shelf-life on food commodities

    International Nuclear Information System (INIS)

    The availability and sustain ability food regarding safety, nutritive, and remaining good palatability are the basic needs of human in order to stay alive and keep healthy. The process must follow the existing standard-guidelines (Good Manufacturing Practices/GMP and Good Irradiation Practices/GIP) if ionizing radiation will be implemented for such purposes because of its effectiveness, efficient, and practical in comparison with conventional methods. Nevertheless application of nuclear technique for improving the safety and extending the shelf-life of foods for human consumption, a proper regulation and legalization from the local government is needed. Commercialization of irradiated food in Indonesia has been stipulated under decree of PERMENKES No. 826/MENKES /PER/XII/1987, No.152/MENKES/SK/II/1995 and Food Law of the Republic of Indonesia No.7/1996. Commercially, besides Indonesia, other countries within Asia and the Pacific region such as India, Thailand, and Vietnam have implemented nuclear technique on food commodities for quarantine, sanitation and sterilization purposes both for local consumption and export to European Countries, USA and Australia. Public education should be more conducted in some effective ways and keep on going to avoid misconception about the technology itself. (author)

  11. Staff′s attitude regarding hospital waste management in the dental college hospitals of Bangalore city, India

    Directory of Open Access Journals (Sweden)

    Sushma Rudraswamy

    2012-01-01

    Full Text Available Background : Growing urbanization has led to several changes in the healthcare sector. While on one hand, access to healthcare services are being provided to the community, thereby resulting in better health for all, improper management of biomedical waste emanating from these healthcare establishments has also given rise to many environmental and health problems (Acharya 2003. Although awareness in this issue has increased considerably over the last few years, sensitivity to this problem has been limited. Most hospitals are not actively involved in addressing this problem. Materials and methods : The present study was conducted to assess the attitude of waste management among staff of dental hospitals in Bangalore city, by issuing a pre-tested structured questionnaire. Results : While 82.6% of attenders said that it is necessary to segregate waste into different categories at the point of origin, 61.5% of auxiliaries strongly disagreed that segregation of waste at source increases the risk of injury to waste handlers. As many as 33.5% of dentists strongly disagreed that segregation of waste at source increases the risk of injury to waste handlers and 53.6% agreed that segregation of waste at source does not increase the risk of injury to waste handlers. Conclusion : The findings of this study suggest that the staff had good attitude towards waste management among.

  12. Adult medulloblastoma: clinical characters, prognostic factors, outcomes and patterns of relapse.

    Science.gov (United States)

    Zhang, Na; Ouyang, Taohui; Kang, Huicong; Long, Wang; Thomas, Benjamin; Zhu, Suiqiang

    2015-09-01

    To analyze the clinical characters, prognostic factors, patterns of relapse and treatment outcomes for medulloblastoma in adults. The clinical materials of 73 consecutive adult patients (age, ≥16 years) with medulloblastoma were analyzed retrospectively. Follow-up data were available in 62 patients, ranging from 10 to 142 months (median, 78.4 months). Outcome in survival was assessed by the progression-free survival (PFS) and overall survival (OS). Univariate and multivariate analysis were performed to determine the prognostic factors. Total or near-total tumor resection was achieved in 37 cases (59.7 %), subtotal in 19 cases (30.6 %), and partial resection in 6 cases (9.7 %).Twenty-two patients experienced recurrences, and 45 % percent of all recurrences occurred more than 4 years after initial surgery. The PFS rates at 5 and 8 years were 60.1 and 37.0 %, respectively. The OS rates at 5 and 8 years were 82.6 and 57.3 %, respectively. In univariate analysis, less tumor resection, non-desmoplastic pathology, and brainstem involvement were risk factors for worse PFS and OS (P medulloblastoma, late relapse is common and therefore long-term follow-up is important for evaluating the real impact of treatments. Risk category had prognostic value just for PFS, but not for OS. Complete resection and desmoplastic histology are independently predictive factors for favorable outcomes. PMID:26026861

  13. 复方蒲公英喷雾剂对奶牛隐性乳房炎的疗效观察%Curative effect of Subclinical Mastitis Using Combination Spray of Dandelion in Dairy Cow

    Institute of Scientific and Technical Information of China (English)

    唐兴刚; 李雪; 李盛强; 郭世宁

    2010-01-01

    运用复方蒲公英喷雾剂对奶牛隐性乳房炎进行疗效观察.将CMT法检测呈阳性的奶牛分3组:复方蒲公英喷雾剂组,中药对照组,空白对照组.给药后用CMT诊断液检测治疗情况.结果发现,复方蒲公英喷雾剂对奶牛隐性乳房炎的治愈率达88.9%,有效率97.2%;中药对照组治愈率56.5%,有效率82.6%.表明复方蒲公英喷雾剂对奶牛隐性乳房炎有良好的治疗效果,使用方便,适于临床应用.

  14. A Case of Increased Density in Rabbit’s Jaw Bone, Evaluated by Cone-Beam Tomography

    Directory of Open Access Journals (Sweden)

    Srđan D. Poštić, PhD

    2013-06-01

    Full Text Available Reduced mineral content affects the trabecular microstructure in the jawbones and skeletons of animals. The aim of this study was to ascertain the benefits in terms of increased bone density in the region of the lateral teeth in the upper and the lower rabbit jaws after application of a therapeutic solution of calcitonin and calcium. The solution was injected to the right side of the maxilla and mandible on the lateral teeth, while the left side was the control. Statistically significant increases in density after application of the therapeutic solution were verified in the experimental regions, in front of the maxillary lateral teeth and around the first maxillary molar (Z=-3.824 and Z=-3.826; p=0.000. ANOVA testing has provided evidence on increasing bone density after the use of a therapeutic solution in the experimental regions of the bone (4.324; df1=7; df2=78.775; p=0.000. Cone beam computed technology (CBCT proved very reliable for assessing the jawbone density in animals, locally applying the additionally therapeutic solution for acceleration of the increment of bone density.

  15. Predictive accuracy of the PanCan lung cancer risk prediction model - external validation based on CT from the Danish Lung Cancer Screening Trial

    International Nuclear Information System (INIS)

    Lung cancer risk models should be externally validated to test generalizability and clinical usefulness. The Danish Lung Cancer Screening Trial (DLCST) is a population-based prospective cohort study, used to assess the discriminative performances of the PanCan models. From the DLCST database, 1,152 nodules from 718 participants were included. Parsimonious and full PanCan risk prediction models were applied to DLCST data, and also coefficients of the model were recalculated using DLCST data. Receiver operating characteristics (ROC) curves and area under the curve (AUC) were used to evaluate risk discrimination. AUCs of 0.826-0.870 were found for DLCST data based on PanCan risk prediction models. In the DLCST, age and family history were significant predictors (p = 0.001 and p = 0.013). Female sex was not confirmed to be associated with higher risk of lung cancer; in fact opposing effects of sex were observed in the two cohorts. Thus, female sex appeared to lower the risk (p = 0.047 and p = 0.040) in the DLCST. High risk discrimination was validated in the DLCST cohort, mainly determined by nodule size. Age and family history of lung cancer were significant predictors and could be included in the parsimonious model. Sex appears to be a less useful predictor. (orig.)

  16. A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4.

    Science.gov (United States)

    Wang, Wucheng; Chen, Huanjun; Zhang, Lei; Qin, Yi; Cong, Qifei; Wang, Peipei; Ding, Kan

    2016-06-25

    A sulfated and acetylated fucoidan, named NDH01, was extracted from seaweed Nemacystus decipiens. NDH01 was composed of mannose, glucuronic acid, fucose, sulfate group and acetyl group in the molar ratio of 3.0: 14.4: 82.6: 34.3: 13.9. The backbone of NDH01 was fucose-free core, composed of α-d-1,2-Manp and β-d-1,4-GlcpA disaccharide repeat unit. The branches were attached at the C3, C4 and C6 of α-d-1,2-Manp. The sidechain was composed of α-l-1,3,4-Fucp, α-l-1,4-Fucp, α-l-1,3-Fucp and α-l-1,4-GlcpA. The sulfate group was linked to C4 of α-l-1,3,4-Fucp, whereas, acetyl group was branched on C2 of α-l-1,2,3-Fucp. NDH01 could disrupt tube formation and inhibit the migration as well as cell growth of human microvascular endothelial cells. Besides, phosphorylation of Smad/1/5/8, Erk and FAK was significantly inhibited by NDH01. Further studies uncovered that NDH01 blocked Smad1/5/8 signaling via interacting with bone morphogenetic protein 4 and downregulating bone morphogenetic protein 4 expression. The results suggested that NDH01 might be an angiogenesis inhibitor through targeting bone morphogenetic protein 4. PMID:27083822

  17. Application of foam column as green technology for concentration of saponins from sisal (Agave sisalana and Juá (Ziziphus joazeiro

    Directory of Open Access Journals (Sweden)

    B. D. Ribeiro

    2013-12-01

    Full Text Available Saponins, molecules classified as triterpenic or steroidal glycosides, are metabolites distributed in all the plant kingdom that can be used for the production of foods, cosmetics, and pharmaceuticals, as well as in soil bioremediation. Saponins are normally extracted from natural resources with water, ethanol and/or methanol, and then concentrated by liquid-liquid partitioning with n-butanol. An alternative concentration method is with a foam column, by which the saponins can be concentrated via preferential adsorption at a gas-liquid interface. Therefore, the objective of this work was the use of a foam column for the concentration of saponins from juá and sisal, evaluating parameters such as: initial working volume in the column, saponin concentration in the extracts from juá and sisal, air flow rate, pH, Raschig rings loading and operation time. When a gradient air flow rate and 25 g of Raschig rings were used, 82.6% of the jua saponins loaded onto the system were recovered in a 3.46-fold concentrated solution after 9 h of operation. Regarding sisal saponins, a concentration factor of 1.98 was observed with 90.5% of saponin recovery during 4.5 h of operation.

  18. Contaminación por metales pesados en los sedimentos acumulados sobre el corredor vial Bogotá - Soacha

    Directory of Open Access Journals (Sweden)

    Carlos Alfonso Zafra Mejía

    2013-09-01

    Full Text Available Road sediments accumulated in dry weather carry metallic elements, which affects water resources when transported by runoff and deteriorates the air quality when suspended by wind and the turbulence induced by traffic. This paper presents the results of a pollution assessment on heavy metal particles associated to road sediment from two particular areas (i.e. Zones 1 and 2 of the Bogotá-Soacha highway (Colombia. Road sediment was collected in each area by direct sweep over a surface of 0.25 m2 and for a period of four months. The concentration of Mn, Fe, Cu, Zn, As, Cd, Ba and Pb was determined per size fraction (less than 250 µm from road sediment. These figures were obtained by means of flame atomic absorption spectrometry and also by using inductively coupled plasma mass spectrometry. The results suggest that the main origin of heavy metals were the mobile sources (i.e. the wear of tires, brake pads and automotive parts. In addition, it is shown that the concentration of Pb and Zn was higher than that allowed by current regulations (used as reference. With regard to urban soils, heavy metals that exceeded the permissible limits were as follows: Pb (21.7 % and 87.0 % of the time in Zones 1 and 2, respectively and Zn (84.8 % and 82.6 % of the time in Zones 1 and 2, respectively.

  19. Loop-mediated isothermal amplification (LAMP) assay for the rapid detection of the sexually-transmitted parasite, Trichomonas vaginalis.

    Science.gov (United States)

    Adao, Davin Edric V; Rivera, Windell L

    2016-01-01

    A loop-mediated isothermal amplification (LAMP) assay was developed to detect the sexually-transmitted parasite, Trichomonas vaginalis in vaginal swabs. The presence of T. vaginalis was detected from 121 female sex workers attending a social hygiene clinic in Balibago, Angeles City, Pampanga, Philippines using culture, polymerase chain reaction (PCR), and the developed LAMP assay. The high analytical sensitivity of LAMP detected a higher prevalence of T. vaginalis (42.06%) compared to culture (8.26%) and PCR (7.44%). Additionally, this assay did not cross-react with DNAs of other trichomonads that can infect humans such as Trichomonas tenax and Pentatrichomonas hominis as well as the pathogens, Candida albicans and Staphylococcus aureus. The LAMP assay developed had a limit of detection (0.036 ng/μl) lower than that of PCR using the primers TvK3 and TvK7 (0.36 ng/μl). Prevalence of T. vaginalis in female sex workers in this area of the Philippines may be higher than previously estimated. Discordant results of PCR and LAMP may be due to different reactions to different kinds of inhibitors in the vaginal swabs. PMID:27262954

  20. Source contributions of PAHs and toxicity in reed wetland soils of Liaohe estuary using a CMB-TEQ method.

    Science.gov (United States)

    Li, Guoliang; Lang, Yinhai; Yang, Wei; Peng, Peng; Wang, Xiaomei

    2014-08-15

    16 US EPA priority PAHs were analyzed in surface soils collected from reed wetland of Liaohe estuary. Total concentrations of the sixteen PAHs ranged from 235 ng g(-1) to 374 ng g(-1), while the total concentrations of seven carcinogenic PAHs (cPAHs) varied from 82.6 ng g(-1) to 109 ng g(-1). Toxicity of PAHs was assessed using toxic equivalent quantity (TEQ). The BaP and DBahA were the major contributors to TEQBaP, although IND showed the highest concentration level. Quantitative source apportionment of PAHs and toxicity (i.e. TEQBaP) were performed, using the CMB-TEQ (chemical mass balance model and TEQ) method. Results showed that, the vehicular sources (gasoline and diesel engine emissions) yielded a higher contribution to TEQBaP (95.7%) than that to PAHs (57.1%), while petrogenic source and biomass burning, two important contributors for total PAHs (21.6% and 21.3%, respectively), contributed a little to TEQBaP (3.6% and 0.7%, respectively).

  1. Production of cellulolytic enzymes by Aspergillus fumigatus ABK9 in wheat bran-rice straw mixed substrate and use of cocktail enzymes for deinking of waste office paper pulp.

    Science.gov (United States)

    Das, Arpan; Paul, Tanmay; Halder, Suman K; Jana, Arijit; Maity, Chiranjit; Das Mohapatra, Pradeep K; Pati, Bikas R; Mondal, Keshab C

    2013-01-01

    Response surface methodology was employed to optimize mixed substrate solid state fermentation for the production of cellulases and xylanase by Aspergillus fumigatus ABK9. Among 11 different parameters, fermentation time (86-88 h), medium pH (6.1-6.2), substrate amount (10.0-10.5 g) and substrate ratio (wheat bran:rice straw) (1.1) had significantly influences on enzyme production. Under these conditions endoglucanase, β-glucosidase, FPase (filter paper degrading activity) and xylanase activities of 826.2, 255.16, 102.5 and 1130.4 U/g, respectively were obtained. The enzyme cocktail extracted (solid to water ratio of 1:10) from the ferments increased brightness of waste office paper pulp by 82.8% ISO, Ink(D) value by 82.1%, removed chromophores (2.53 OD; A(237)nm) and hydrophobic compounds (1.15 OD; A(465)nm) and also decreased the kappa number to 13.5 from 16.8. PMID:23196251

  2. Hyper abundant mesopredators and bird extinction in an Atlantic forest island

    Directory of Open Access Journals (Sweden)

    Mauro Galetti

    2009-06-01

    Full Text Available Islands can serve as model systems for understanding how biological invasions affect native species. Here we examine the negative effects of mesopredator mammals on bird richness at Anchieta Island, an 826 ha offshore island in the coast of Brazil. Anchieta Island has the highest density of mammals of the entire Atlantic forest, especially nest predators such as marmosets and coatis, introduced more than 20 years ago. This indiscriminate introduction of mammals may have affected directly the bird community, nowadays represented by 100 species comprised mainly by water-crossing birds, being 73 forest-dwelling species. A small component of these remnant bird species nests in tree holes and on the forest floor, null model analysis suggest that birds within these two nest types are under-represented on Anchieta Island. All guilds were affected negatively, but "opportunist insectivorous/omnivorous". Experiments using artificial nests showed a predation of 73% of nests on the floor while only 26% on the mainland. Camera traps recorded predation by coatis, agoutis, and opossums. The restoration of the bird community on this island is highly constrained by the high density of hyper abundant nest predators.

  3. Paraoxonase1 Genetic Polymorphisms in a Mixed Ancestry African Population

    Directory of Open Access Journals (Sweden)

    M. Macharia

    2014-01-01

    Full Text Available Paraoxonase 1 (PON1 activity is markedly influenced by coding polymorphisms, Q/R at position 192 and M/L at position 55 of the PON1 gene. We investigated the frequencies of these polymorphisms and their effects on PON1 and antioxidant activities in 844 South African mixed ancestry individuals. Genotyping was done using allele-specific TaqMan technology, PON1 activities were measured using paraoxon and phenylacetate, oxidative status was determined by measuring the antioxidant activities of ferric reducing antioxidant power and trolox equivalent antioxidant capacity, and lipid peroxidation markers included malondialdehyde and oxidized LDL. The frequencies of Q192R and L55M were 47.6% and 28.8%, respectively, and the most common corresponding alleles were 192R (60.4% and 55M (82.6%. The Q192 was significantly associated with 5.8 units’ increase in PON1 concentration and 15.4 units’ decrease in PONase activity after adjustment for age, sex, BMI, and diabetes, with suggestion of differential effects by diabetes status. The PON1 L55 variant was associated with none of the measured indices. In conclusion, we have shown that the Q192R polymorphism is a determinant of both PON1 concentration and activity and this association appeared to be enhanced in subjects with diabetes.

  4. Can Artificial Neural Networks be Applied in Seismic Predicition? Preliminary Analysis Applying Radial Topology. Case: Mexico

    CERN Document Server

    Mota-Hernandez, Cinthya; Alvarado-Corona, Rafael

    2014-01-01

    Tectonic earthquakes of high magnitude can cause considerable losses in terms of human lives, economic and infrastructure, among others. According to an evaluation published by the U.S. Geological Survey, 30 is the number of earthquakes which have greatly impacted Mexico from the end of the XIX century to this one. Based upon data from the National Seismological Service, on the period between January 1, 2006 and May 1, 2013 there have occurred 5,826 earthquakes which magnitude has been greater than 4.0 degrees on the Richter magnitude scale (25.54% of the total of earthquakes registered on the national territory), being the Pacific Plate and the Cocos Plate the most important ones. This document describes the development of an Artificial Neural Network (ANN) based on the radial topology which seeks to generate a prediction with an error margin lower than 20% which can inform about the probability of a future earthquake one of the main questions is: can artificial neural networks be applied in seismic forecast...

  5. AGU journals continue to rank highly in Impact Factors

    Science.gov (United States)

    Sears, Jon; Warner, Mary

    2012-07-01

    AGU journals continue to rank highly in the 2011 Journal Citation Reports (JCR), which was released by Thomson Reuters on 28 June. The impact factor of several AGU journals increased significantly, continuing their trend over the previous 5 years, while others remained consistent with the previous year's ranking. Paleoceanography is an outstanding performer in both the Paleontology and Oceanography categories. Since 1995, Paleoceanography has been the top-ranked journal in the Paleontology category (of 49 titles in 2011), with an Impact Factor of 3.357. In the Oceanography group (59 journals total), Paleoceanography ranks third in Impact Factor. Reviews of Geophysics, with an Impact Factor of 12.364 (an increase of 2.826 from the prior year's score of 9.538), ranks second in Geochemistry and Geophysics out of a total of 77 journals in this cohort. Water Resources Research comes in at second place in the Limnology group, with 19 titles, and third place in the Water Resources group, which has a cohort of 78 titles.

  6. Voluntary Cough Airflow Differentiates Safe Versus Unsafe Swallowing in Amyotrophic Lateral Sclerosis.

    Science.gov (United States)

    Plowman, Emily K; Watts, Stephanie A; Robison, Raele; Tabor, Lauren; Dion, Charles; Gaziano, Joy; Vu, Tuan; Gooch, Clifton

    2016-06-01

    Dysphagia and aspiration are prevalent in amyotrophic lateral sclerosis (ALS) and contribute to malnutrition, aspiration pneumonia, and death. Early detection of at risk individuals is critical to ensure maintenance of safe oral intake and optimal pulmonary function. We therefore aimed to determine the discriminant ability of voluntary cough airflow measures in detecting penetration/aspiration status in ALS patients. Seventy individuals with ALS (El-Escorial criteria) completed voluntary cough spirometry testing and underwent a standardized videofluoroscopic swallowing evaluation (VFSE). A rater blinded to aspiration status derived six objective measures of voluntary cough airflow and evaluated airway safety using the penetration-aspiration scale (PAS). A between groups ANOVA (safe vs. unsafe swallowers) was conducted and sensitivity, specificity, area under the curve (AUC) and likelihood ratios were calculated. VFSE analysis revealed 24 penetrator/aspirators (PAS ≥3) and 46 non-penetrator/aspirators (PAS ≤2). Cough volume acceleration (CVA), peak expiratory flow rise time (PEFRT), and peak expiratory flow rate (PEFR) were significantly different between airway safety groups (p 76 ms had sensitivities of 91.3, 82.6, and 73.9 %, respectively, and specificities of 82.2, 73.9, and 78.3 % for identifying ALS penetrator/aspirators. Voluntary cough airflow measures identified ALS patients at risk for penetration/aspiration and may be a valuable screening tool with high clinical utility. PMID:26803772

  7. ECH system and its application to long pulse discharge in large helical device

    International Nuclear Information System (INIS)

    We have developed and constructed an ECH system for the large helical device (LHD). The ECH system consists of 0.5 MW, 84 GHz range and 168 GHz gyrotrons, high voltage power supplies, long distance transmission lines, and in-vessel quasi-optical antennas. It has been improved step by step. At the third campaign of LHD experiments, three 84 GHz range (two 82.6 GHz and one 84 GHz) and three 168 GHz gyrotrons are operated and ECH power can be injected from four antennas vertically and two horizontally. This complicated system is remotely controlled and monitored by fully GUI (Graphical User Interface) control panels realized on PC via TCP (transmission control protocol) communication. Over 10000 shots of gyrotron power have been injected steadily into the LHD during the experimental campaigns on this system. One line of the system (84 GHz line) is specially prepared for the experiments of steady state plasma production. Using this line, plasma sustainment for 2 min was successfully achieved by only ECH power. Injected ECH power was 50 kW with 95% duty factor. The electron density and temperature of the sustained plasma are measured to be 0.3-0.5x1018 m-3 and ∼650 eV. Ion temperature measured by Doppler broadening of the impurity radiation line was kept constant at ∼300 eV during RF injection

  8. Relationship between Hyperuricemia and Haar-Like Features on Tongue Images

    Directory of Open Access Journals (Sweden)

    Yan Cui

    2015-01-01

    Full Text Available Objective. To investigate differences in tongue images of subjects with and without hyperuricemia. Materials and Methods. This population-based case-control study was performed in 2012-2013. We collected data from 46 case subjects with hyperuricemia and 46 control subjects, including results of biochemical examinations and tongue images. Symmetrical Haar-like features based on integral images were extracted from tongue images. T-tests were performed to determine the ability of extracted features to distinguish between the case and control groups. We first selected features using the common criterion P<0.05, then conducted further examination of feature characteristics and feature selection using means and standard deviations of distributions in the case and control groups. Results. A total of 115,683 features were selected using the criterion P<0.05. The maximum area under the receiver operating characteristic curve (AUC of these features was 0.877. The sensitivity of the feature with the maximum AUC value was 0.800 and specificity was 0.826 when the Youden index was maximized. Features that performed well were concentrated in the tongue root region. Conclusions. Symmetrical Haar-like features enabled discrimination of subjects with and without hyperuricemia in our sample. The locations of these discriminative features were in agreement with the interpretation of tongue appearance in traditional Chinese and Western medicine.

  9. Encapsulation in alginate and alginate coated-chitosan improved the survival of newly probiotic in oxgall and gastric juice.

    Science.gov (United States)

    Trabelsi, Imen; Bejar, Wacim; Ayadi, Dorra; Chouayekh, Hichem; Kammoun, Radhouane; Bejar, Samir; Ben Salah, Riadh

    2013-10-01

    This study was undertaken to develop an optimum composition model for the microencapsulation of a newly probiotic on sodium alginate using response surface methodology. The individual and interactive effects of three independent variables, namely sodium alginate concentration, biomass concentration, and hardening time, were investigated using Box-Behnken design experiments. A second ordered polynomial model was fitted and optimum conditions were estimated. The optimal conditions identified were 2% for sodium alginate, 10(10)UFC/ml for biomass, and 30 min for hardening time. The experimental value obtained for immobilized cells under these conditions was about 80.98%, which was in close agreement with the predicted value of 82.6%. Viability of microspheres (96%) was enhanced with chitosan as coating materials. The survival rates of free and microencapsulated Lactobacillus plantarum TN8 during exposure to artificial gastrointestinal conditions were compared. The results revealed that the encapsulated cells exhibited significantly higher resistances to artificial intestinal juice (AIJ) and artificial gastric juice (AGJ). Microencapsulation was also noted to effectively protect the strain from heating at 65 °C and refrigerating at 4 °C. Taken together, the findings indicated that microencapsulation conferred important protective effects to L. plantarum against the gastrointestinal conditions encountered during the transit of food.

  10. Comparison of the diagnostic performance of panoramic and occlusal radiographs in detecting submandibular sialoliths

    Science.gov (United States)

    Kim, Jun Ho; Aoki, Eduardo Massaharu; Abdala-Júnior, Reinaldo; Asaumi, Junichi; Arita, Emiko Saito

    2016-01-01

    Purpose The aim of this study was to assess and compare the diagnostic performance of panoramic and occlusal radiographs in detecting submandibular sialoliths. Materials and Methods A total of 40 patients (20 cases and 20 controls) were included in this retrospective study. Cases were defined as subjects with a submandibular sialolith confirmed by computed tomography (CT), whereas controls did not have any submandibular calcifications. Three observers with different expertise levels assessed panoramic and occlusal radiographs of all subjects for the presence of sialoliths. Intraobserver and interobserver agreement were assessed using the kappa test. Sensitivity, specificity, accuracy, positive and negative predictive values, and the diagnostic odds ratio of panoramic and occlusal radiographs in screening for submandibular sialoliths were calculated for each observer. Results The sensitivity and specificity values for occlusal and panoramic radiographs all ranged from 80% to 100%. The lowest values of sensitivity and specificity observed among the observers were 82.6% and 80%, respectively (P=0.001). Intraobserver and interobserver agreement were higher for occlusal radiographs than for panoramic radiographs, although panoramic radiographs demonstrated a higher overall accuracy. Conclusion Both panoramic and occlusal radiographic techniques displayed satisfactory diagnostic performance and should be considered before using a CT scan to detect submandibular sialoliths. PMID:27358815

  11. DETERMINATION OF FORMALDEHYDE LEVELS IN 46 COFFEE SHOPS IN ANKARA

    Directory of Open Access Journals (Sweden)

    Songul Acar VAIZOÐLU

    2005-06-01

    Full Text Available This study is a descriptive research performed in order to measure formaldehyde levels in 46 random selected coffee shops in from central districts of Ankara. Formaldemeter 400 was used for formaldehyde measures. Simultaneous measures were applied in coffee shops. Mean of formaldehyde levels was 0,20 ppm. There was artificial ventilation in all of the coffee shops. It was used aspirator as ventilation device in 69,6% of the coffee shops. But in 81,0% of these, the formaldehyde levels were above 0,10 ppm. In 51,0% of the shops stoves were used for warming and 95,7% of these formaldehyde levels were above 0,10 ppm. There were statistically significant difference between warming-up method and formaldehyde levels of coffee shops ( p<0,05, chi square = 6,4. It was used liquid fuel in 51,1% of them as heating fuel. In 69,6% of them formaldehyde levels were above 0,10 ppm. There were statistically significant difference between fuel type and formaldehyde levels of coffee shops ( p<0,05, chi square = 5,7. As a result; in 91,3% of the coffee shops formaldehyde levels were above the 0,03 ppm which is permitted limit for indoors, and in 82,6% of them formaldehyde levels were above the 0,1 ppm which is symptom producing level. [TAF Prev Med Bull 2005; 4(3.000: 129-135

  12. Predictive accuracy of the PanCan lung cancer risk prediction model - external validation based on CT from the Danish Lung Cancer Screening Trial

    Energy Technology Data Exchange (ETDEWEB)

    Winkler Wille, Mathilde M.; Dirksen, Asger [Gentofte Hospital, Department of Respiratory Medicine, Hellerup (Denmark); Riel, Sarah J. van; Jacobs, Colin; Scholten, Ernst T.; Ginneken, Bram van [Radboud University Medical Center, Department of Radiology and Nuclear Medicine, Nijmegen (Netherlands); Saghir, Zaigham [Herlev Hospital, Department of Respiratory Medicine, Herlev (Denmark); Pedersen, Jesper Holst [Copenhagen University Hospital, Department of Thoracic Surgery, Rigshospitalet, Koebenhavn Oe (Denmark); Hohwue Thomsen, Laura [Hvidovre Hospital, Department of Respiratory Medicine, Hvidovre (Denmark); Skovgaard, Lene T. [University of Copenhagen, Department of Biostatistics, Koebenhavn Oe (Denmark)

    2015-10-15

    Lung cancer risk models should be externally validated to test generalizability and clinical usefulness. The Danish Lung Cancer Screening Trial (DLCST) is a population-based prospective cohort study, used to assess the discriminative performances of the PanCan models. From the DLCST database, 1,152 nodules from 718 participants were included. Parsimonious and full PanCan risk prediction models were applied to DLCST data, and also coefficients of the model were recalculated using DLCST data. Receiver operating characteristics (ROC) curves and area under the curve (AUC) were used to evaluate risk discrimination. AUCs of 0.826-0.870 were found for DLCST data based on PanCan risk prediction models. In the DLCST, age and family history were significant predictors (p = 0.001 and p = 0.013). Female sex was not confirmed to be associated with higher risk of lung cancer; in fact opposing effects of sex were observed in the two cohorts. Thus, female sex appeared to lower the risk (p = 0.047 and p = 0.040) in the DLCST. High risk discrimination was validated in the DLCST cohort, mainly determined by nodule size. Age and family history of lung cancer were significant predictors and could be included in the parsimonious model. Sex appears to be a less useful predictor. (orig.)

  13. Role of serum total sialic acid in differentiating cholangiocarcinoma from hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    Prachya Kongtawelert; Pisit Tangkijvanich; Siriwan Ong-Chai; Yong Poovorawan

    2003-01-01

    AIM:This study was designed to evaluate the clinical application of serum total sialic acid (TSA) in the diagnosis of cholangiocarcinoma (CCA).METHODS: Serum TSA was determined by periodateresorcinol microassay in 69 patients with CCA, 59 patients with hepatocellular carcinoma (HCC), 37 patients with cirrhosis, 61 patients with chronic hepatitis and 50 healthy blood donors.RESULTS: The mean serum TSA concentration in CCA (2.41±0.70 mmol/L) was significantly higher than those of HCC, cirrhosis, chronic hepatitis and healthy blood donors (1.41±0.37 mmol/L, 1.13±0.31 mmol/L, 1.16±0.26 mmol/L, and 1.10±0.14 mmol/L, respectively; P<0.001). Based on ROC curve analysis, a cut-off point of 1.75 mmol/L discriminated between CCA and HCC with a sensitivity,specificity and accuracy of 82.6%, 83.1%, and 82.8%,respectively.CONCLUSION: Based on our results, serum TSA would be a useful marker for the differential diagnosis of CCA from HCC.

  14. 之字链聚合物[Zn(o-bda)(phen)(H2O)]n·nH2O的结构%Crystal Structure of a Zigzag Chain [Zn(o-bda)(phen)(H2O)]n·nH2O

    Institute of Scientific and Technical Information of China (English)

    杨燕; 曾明华; 蒙法艳; 邓前军; 梁宏; 张淑华

    2007-01-01

    [Zn(o-bda)(phen)(H2O)] ·H2O (C22H20N2O6Zn) (1) [where o-bda is o-phenylenediacetic acid dianion and phen is 1,10-phenanthroline] crystallizes in triclinic system, space group P1 with a=0.826 5 (4) nm, b=1.0424(5)nm, c=1.238 1(6) nm, α=76.987(9)°,β=70.987(9)°, γ=78.281(8)°, V=0.9728(8) nm3, Z=2, Dc=1.617 g·cm-3,μ=1.308 mm-1 and F(000)=488. Zn(Ⅱ) ion has a distorted trigonal bipyramid coordination geometry formed by two carboxyl O atoms from two different o-bda groups, two N atoms from the phen ligand and one terminal water molecule. Adjacent Zn(Ⅱ) ions are interlinked by o-bda groups into a infinite zigzag chain structure with a Zn…Zn distance of 0.825 6(4) nm. The adjacent zigzag chains may also be paired under direction of supramolecular recognition and attraction through both π-π stacking and hydrogen bonding interactions into molecular zippers,which further interlinked into a three-dimensional supramolecular network by these noncovalent interactions.CCDC:600935.

  15. St. Louis demonstration final report: refuse processing plant equipment, facilities, and environmental evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Fiscus, D.E.; Gorman, P.G.; Schrag, M.P.; Shannon, L.J.

    1977-09-01

    The results are presented of processing plant evaluations of the St. Louis-Union Electric Refuse Fuel Project, including equipment and facilities as well as assessment of environmental emissions at both the processing and the power plants. Data on plant material flows and operating parameters, plant operating costs, characteristics of plant material flows, and emissions from various processing operations were obtained during a testing program encompassing 53 calendar weeks. Refuse derived fuel (RDF) is the major product (80.6% by weight) of the refuse processing plant, the other being ferrous metal scrap, a marketable by-product. Average operating costs for the entire evaluation period were $8.26/Mg ($7.49/ton). The average overall processing rate for the period was 168 Mg/8-h day (185.5 tons/8-h day) at 31.0 Mg/h (34.2 tons/h). Future plants using an air classification system of the type used at the St. Louis demonstration plant will need an emissions control device for particulates from the large de-entrainment cyclone. Also in the air exhaust from the cyclone were total counts of bacteria and viruses several times higher than those of suburban ambient air. No water effluent or noise exposure problems were encountered, although landfill leachate mixed with ground water could result in contamination, given low dilution rates.

  16. Factores de riesgo para infarto agudo de miocardio y prescripción de medicamentos para prevención secundaria

    Directory of Open Access Journals (Sweden)

    Desirée Sáenz-Campos

    2005-01-01

    Full Text Available Objetivo: tipificar algunos factores de riesgo coronario presentes en los pacientes que sobreviven a un primer infarto agudo de miocardio (IAM y describir el tratamiento farmacológico prescrito para profilaxis secundaria al egreso hospitalario. Métodos: estudio observacional, transversal y descriptivo, con información extraída del expediente clínico de 50 pacientes atendidos en 3 hospitales nacionales. Resultados: 42 varones y 8 mujeres, edad 63 ± 15 años, peso 67 ± 12 kg, Índice de Masa Corporal= 26.1 ± 2.1 kg/m², 38% hipertensos, 22% diabéticos (n= 8 pacientes con diabetes + hipertensión y 34% fumadores. Colesterol total 191 ± 45.7 mg/dL, colesterol-LDL 112 ± 33.8 mg/dL y colesterol-HDL 39.4 ± 8.26 mg/dL. Todos egresaron con medicamentos: 92% con antitrombóticos (predominó aspirina, 92% con estatinas, 78% con betabloqueador (atenolol o carvedilol, 70% con enalapril o losartán y 48% con nitratos. Conclusiones: este estudio piloto mostró que la enfermedad coronaria tiende a manifestarse desde la etapa de adulto joven, persiste en su mayor afectación a los varones y parecen prevalecer los factores de riesgo coronario modificables. Los antitrombóticos, beta- bloqueadores y las estatinas más frecuentemente prescritos.

  17. Optimization of Maillard reaction with ribose for enhancing anti-allergy effect of fish protein hydrolysates using response surface methodology.

    Science.gov (United States)

    Yang, Sung-Yong; Kim, Se-Wook; Kim, Yoonsook; Lee, Sang-Hoon; Jeon, Hyeonjin; Lee, Kwang-Won

    2015-06-01

    Halibut is served on sushi and as sliced raw fish fillets. We investigated the optimal conditions of the Maillard reaction (MR) with ribose using response surface methodology to reduce the allergenicity of its protein. A 3-factored and 5-leveled central composite design was used, where the independent variables were substrate (ribose) concentration (X1, %), reaction time (X2, min), and pH (X3), while the dependent variables were browning index (Y1, absorbance at 420nm), DPPH scavenging (Y2, EC50 mg/mL), FRAP (Y3, mM FeSO4/mg extract) and β-hexosaminidase release (Y4, %). The optimal conditions were obtained as follows: X1, 28.36%; X2, 38.09min; X3, 8.26. Maillard reaction products of fish protein hydrolysate (MFPH) reduced the amount of nitric oxide synthesis compared to the untreated FPH, and had a significant anti-allergy effect on β-hexosaminidase and histamine release, compared with that of the FPH control. We concluded that MFPH, which had better antioxidant and anti-allergy activities than untreated FPH, can be used as an improved dietary source. PMID:25624251

  18. Testing General Relativity with Growth rate measurement from Sloan Digital Sky Survey Baryon Oscillations Spectroscopic Survey galaxies

    CERN Document Server

    Alam, Shadab; Vargas-Magaña, Mariana; Schneider, Donald P

    2015-01-01

    The measured redshift ($z$) of an astronomical object is a combination of Hubble recession, gravitational redshift and peculiar velocity. In particular, the line of sight distance to a galaxy inferred from redshift is affected by the peculiar velocity component of galaxy redshift, which can also be observed as an anisotropy in the correlation function. This anisotropy allows us to measure the linear growth rate of matter ($f\\sigma_8$). In this paper, we measure the linear growth rate of matter ($f\\sigma_8$) at $z=0.57$ using the CMASS sample from Data Release 11 of Sloan Digital Sky Survey III (SDSS III) Baryon Oscillations Spectroscopic Survey (BOSS). The galaxy sample consists of 690,826 Luminous Red Galaxies (LRGs) in the redshift range 0.43 to 0.7 covering 8498 deg$^2$. Here we report the first measurement of $f\\sigma_8$ and cosmology using Convolution Lagrangian Perturbation Theory (CLPT) with Gaussian streaming model (GSRSD). We arrive at a constraint of $f\\sigma_8=0.462\\pm0.041$ (9\\% accuracy) at effec...

  19. IN VITRO CYTOTOXICITY STUDY OF AGAVE AMERICANA, STRYCHNOS NUX-VOMICA AND ARECA CATECHU EXTRACTS USING MCF-7 CELL LINE

    Directory of Open Access Journals (Sweden)

    Anajwala Chetan C.

    2010-06-01

    Full Text Available Research is focusing on the search for new types of natural chemotherapeutic agent that is plant based medicines which are proving to be excellent sources of new compounds. In present research study, an attempt was made to prove cytotoxicity activity of various parts of medicinal plants such as Agave americana, Strychnos nux-vomica and Areca catechu using MCF-7 and Vero cell line. Various parts of the medicinal plants were extracted by soxhlet apparatus using solvents likes methanol and water. By trypan blue dye exclusion method, Viability of MCF-7 and Vero cell lines were 85.50 and 81.13%, respectively. IC50 value of methanol extract of Agave americana leaves and aqueous extract of Areca catechu fruits were found to be 545.9 & 826.1 µg/ml by SRB assay and 775.1 & 1461µg/ml by MTT assay, respectively, against MCF-7 cell line. From cytotoxicity study data by SRB and MTT assay, it revealed that methanol extract of Agave americana and aqueous extract of Areca catechu are potent cytotoxic.

  20. The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist

    Energy Technology Data Exchange (ETDEWEB)

    Madauss, Kevin P.; Burkhart, William A.; Consler, Thomas G.; Cowan, David J.; Gottschalk, William K.; Miller, Aaron B; Short, Steven A.; Tran, Thuy B.; Williams, Shawn P.; (GSKNC); (Duke); (UNC)

    2009-06-15

    Inhibition of acetyl-CoA carboxylase (ACC) may prevent lipid-induced insulin resistance and type 2 diabetes, making the enzyme an attractive pharmaceutical target. Although the enzyme is highly conserved amongst animals, only the yeast enzyme structure is available for rational drug design. The use of biophysical assays has permitted the identification of a specific C-terminal truncation of the 826-residue human ACC2 carboxyl transferase (CT) domain that is both functionally competent to bind inhibitors and crystallizes in their presence. This C-terminal truncation led to the determination of the human ACC2 CT domain-CP-640186 complex crystal structure, which revealed distinctions from the yeast-enzyme complex. The human ACC2 CT-domain C-terminus is comprised of three intertwined -helices that extend outwards from the enzyme on the opposite side to the ligand-binding site. Differences in the observed inhibitor conformation between the yeast and human structures are caused by differing residues in the binding pocket.

  1. Differences in Urinary Arsenic Metabolites between Diabetic and Non-Diabetic Subjects in Bangladesh

    Directory of Open Access Journals (Sweden)

    Tamie Nakajima

    2013-03-01

    Full Text Available Ingestion of inorganic arsenic (iAs is considered to be related to the development of diabetes mellitus. In order to clarify the possible differences in the metabolism in diabetics, we measured urinary iAs metabolites in diabetic cases and non-diabetic control subjects in Faridpur, an arsenic-contaminated area in Bangladesh. Physician-diagnosed type 2 diabetic cases (140 persons and non-diabetic controls (180 persons were recruited. Drinking water and spot urine samples were collected. Mean concentrations of total arsenic in drinking water did not differ between cases (85.1 μg/L and controls (85.8 μg/L. The percentage of urinary iAs (iAs% was significantly lower in cases (8.6% than in controls (10.4%, while that of dimethylarsinic acid (DMA% was higher in cases (82.6% than in controls (79.9%. This may have been due to the higher secondary methylation index (SMI in the former (11.6 rather than the latter (10.0. Adjusting for matching factors (sex and unions, and the additional other covariates (age and water arsenic significantly attenuated the differences in iAs%, SMI, and DMA%, respectively, though the difference in monomethylarsonic acid% was newly significant in the latter adjustment. Our study did not suggest any significant differences in urinary arsenic metabolites between diabetic and non-diabetic subjects.

  2. Comparative in vitro evaluation of CAD/CAM vs conventional provisional crowns

    Science.gov (United States)

    ABDULLAH, Adil Othman; TSITROU, Effrosyni A; POLLINGTON, Sarah

    2016-01-01

    ABSTRACT Objective This study compared the marginal gap, internal fit, fracture strength, and mode of fracture of CAD/CAM provisional crowns with that of direct provisional crowns. Material and Methods An upper right first premolar phantom tooth was prepared for full ceramic crown following tooth preparation guidelines. The materials tested were: VITA CAD-Temp®, Polyetheretherketone “PEEK”, Telio CAD-Temp, and Protemp™4 (control group). The crowns were divided into four groups (n=10), Group1: VITA CAD-Temp®, Group 2: PEEK, Group 3: Telio CAD-Temp, and Group 4: Protemp™4. Each crown was investigated for marginal and internal fit, fracture strength, and mode of fracture. Statistical analysis was performed using GraphPad Prism software version 6.0. Results The average marginal gap was: VITA CAD-Temp® 60.61 (±9.99) µm, PEEK 46.75 (±8.26) µm, Telio CAD-Temp 56.10 (±5.65) µm, and Protemp™4 193.07(±35.96) µm (P0.05). Conclusions CAD/CAM fabricated provisional crowns demonstrated superior fit and better strength than direct provisional crowns. PMID:27383707

  3. Corrosion leaking of preheater weldment in alumina factories

    Institute of Scientific and Technical Information of China (English)

    ZHANG Li; CHEN Wen-mi; GONG Zhu-qing; LIU Hong-zhao

    2005-01-01

    Stress corrosion cracking (SCC) and anticorrosion measures of TU42C weld-joint were studied by constant load experiments and pickling experiments. The results show that in 40%(mass fraction) NaOH solution at 110 ℃, caustic SCC occurs in TU42C weld-joints at the applied potential of -1 020 mV(vs SCE) for 3 d while at the potential of -950 mV(vs SCE) for 10 d. All the cracks are intergranular. In the 10% sulfuric acid, the cracks have the most negative self-corrosion potential -432.5 mV(vs SCE) and are active to be further corroded by the acid. Because of the same corrosion behaviour as the lab weldment, preheater's cracking in alumina factories is attributed to the combining actions of previous caustic SCC in Bayer solutions and continuous acid corrosion by pickling with the addition of RD. The following measures are effective to prevent the corrosion failure of preheater, such as postweld heat treatment at 620 ℃ to relax the residual weld stress, addition of CC3 and L826 as the corrosion inhibitors to improve the pickling and cleaning by the high pressure water instead of by pickling.

  4. Simultaneous nitrogen and phosphorus removal by a novel sequencing batch moving bed membrane bioreactor for wastewater treatment

    Energy Technology Data Exchange (ETDEWEB)

    Yang Shuai [Key Laboratory of Industrial Ecology and Environmental Engineering, MOE, School of Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024 (China); Yang Fenglin, E-mail: yangshuai1125@163.com [Key Laboratory of Industrial Ecology and Environmental Engineering, MOE, School of Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024 (China); Fu Zhimin; Wang Tao [Key Laboratory of Industrial Ecology and Environmental Engineering, MOE, School of Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024 (China); Lei Ruibo [State Key Laboratory of Coastal and Offshore Engineering, School of Civil and Hydraulic Engineering, Dalian University of Technology, Dalian 116024 (China)

    2010-03-15

    Biological nutrient removal (BNR) was investigated in a sequencing batch membrane bioreactor which used carriers instead of activated sludge named a sequencing batch moving bed membrane bioreactor (SBMBMBR). The SBMBMBR performed well on carbon and nitrogen removal at different COD/TN ratios. COD, TN and ammonium nitrogen removal efficiencies averaged at 93.5%, 82.6% and 95.6%, respectively. The TP removal was closely correlated with the length of anaerobic phase and aerobic phase. When anaerobic time and aerobic time were both 2 h, the average TP removal efficiency reached to 84.1% at influent TP concentration of 12.4 mg/L. DO in aerobic phase was an important factor affecting nutrient removal, and the optimal DO was about 3 mg/L. There was a small amount of denitrifying phosphorus accumulating organisms (DPAOs) in SBMBMBR which resulted from the anoxic microenvironment existed in the inner of the biofilm. Fluorescence in situ hybridization (FISH) results of microbes showed the composition and spatial structure of the microbial community in the reactor. Furthermore, sequencing batch mode operation was propitious to retard membrane fouling.

  5. Phosphorus removal and recovery from domestic wastewater in a novel process of enhanced biological phosphorus removal coupled with crystallization.

    Science.gov (United States)

    Zou, Haiming; Wang, Yan

    2016-07-01

    A new process of enhanced biological phosphorus removal coupled with crystallization recovery of phosphorus was developed here, where the feasibility of nutrients removal and potential for phosphorus recovery from domestic wastewater was further assessed. Results showed that an excellent nutrients removal and phosphorus recovery performance was achieved, in which the averaged COD, PO4(3-)-P and NO3(-)-N removal efficiencies were 82.6%, 87.5% and 91.6%, respectively and a total of 59.3% of phosphorus was recovered as hydroxyapatite. What's more, crystallization recovery of phosphorus greatly enhanced the biological phosphorus removal efficiency. After the incorporation of the phosphorus recovery column via side-stream, the phosphorus concentration of effluent was significantly decreased ranging from 1.24mg/L to 0.85mg/L, 0.52mg/L and 0.41mg/L at the lateral flow ratios of 0, 0.1, 0.2 and 0.3, respectively. The results obtained here would be beneficial to provide a prospective alternative for phosphorus removal and recovery from wastewater. PMID:27003794

  6. Proteomics shows Hsp70 does not bind peptide sequences indiscriminately in vivo

    International Nuclear Information System (INIS)

    Heat shock protein 70 (Hsp70) binds peptide and has several functions that include protein folding, protein trafficking, and involvement with immune function. However, endogenous Hsp70-binding peptides had not previously been identified. Therefore, we eluted and identified several hundred endogenously bound peptides from Hsp70 using liquid chromatography ion trap mass spectrophotometry (LC-ITMS). Our work shows that the peptides are capable of binding Hsp70 as previously described. They are generally 8-26 amino acids in length and correspond to specific regions of many proteins. Through computationally assisted analysis of peptides eluted from Hsp70 we determined variable amino acid sequences, including a 5 amino acid core sequence that Hsp70 favorably binds. We also developed a computer algorithm that predicts Hsp70 binding within proteins. This work helps to define what peptides are bound by Hsp70 in vivo and suggests that Hsp70 facilitates peptide selection by aiding a funneling mechanism that is flexible but allows only a limited number of peptides to be processed

  7. Skin sites to predict deep-body temperature while wearing firefighters' personal protective equipment during periodical changes in air temperature.

    Science.gov (United States)

    Kim, Siyeon; Lee, Joo-Young

    2016-04-01

    The aim of this study was to investigate stable and valid measurement sites of skin temperatures as a non-invasive variable to predict deep-body temperature while wearing firefighters' personal protective equipment (PPE) during air temperature changes. Eight male firefighters participated in an experiment which consisted of 60-min exercise and 10-min recovery while wearing PPE without self-contained breathing apparatus (7.75 kg in total PPE mass). Air temperature was periodically fluctuated from 29.5 to 35.5 °C with an amplitude of 6 °C. Rectal temperature was chosen as a deep-body temperature, and 12 skin temperatures were recorded. The results showed that the forehead and chest were identified as the most valid sites to predict rectal temperature (R(2) = 0.826 and 0.824, respectively) in an environment with periodically fluctuated air temperatures. This study suggests that particular skin temperatures are valid as a non-invasive variable when predicting rectal temperature of an individual wearing PPE in changing ambient temperatures. Practitioner Summary: This study should offer assistance for developing a more reliable indirect indicating system of individual heat strain for firefighters in real time, which can be used practically as a precaution of firefighters' heat-related illness and utilised along with physiological monitoring.

  8. Comparison of microhabitats and foraging strategies between the captive-born Zhangxiang and wild giant pandas: implications for future reintroduction.

    Science.gov (United States)

    Lei, Miaowen; Yuan, Shibin; Yang, Zisong; Hong, Mingsheng; Yang, Xuyu; Gu, Xiaodong; Huang, Feng; Zhang, Zejun

    2015-10-01

    The female giant panda Zhangxiang (pedigree number 826) was born on August 20, 2011 in Wolong Nature Reserve, China. On November 6, 2013, Zhangxiang was transported into the acclimatization enclosure in the Liziping Nature Reserve. Before Zhangxiang left the enclosure into the wild, we conducted the first study to compare microhabitats and foraging strategies between Zhangxiang in the enclosure and giant pandas in the wild. Compared with the latter, microhabitats of Zhangxiang in the enclosure are characteristic of gentler slope, more trees, higher canopy, smaller tree DBH, and lower density of living bamboos. Diet composition and foraging behaviors significantly differed between Zhangxiang and wild giant pandas, perhaps reflecting the combined consequence of environmental conditions (e.g., bamboo species) and individual status (e.g., age, mastication ability, etc.). The difference in microhabitats and foraging strategies between Zhangxiang and wild giant pandas implied that after being released into the natural habitat in the reserve, Zhangxiang will have to adapt to the environmental conditions once again. For future reintroduction, the enclosure can be extended to the Bashania spanostachya forest in the reserve, and captive giant pandas for release can thus normally transit into the wild without human intervention during acclimatization period. For other acclimatization enclosures to be constructed in the future, ecological environment inside, including topography, forests, and bamboos as well, should as possible as can match the habitat that the giant panda to-be-reinforced populations inhabit. PMID:26003090

  9. Cloning, sequencing and identification of single nucleotide polymorphisms of partial sequence on the porcine CACNA1S gene

    Institute of Scientific and Technical Information of China (English)

    FANG XiaoMin; XU NingYing; REN ShouWen

    2008-01-01

    CACNA1S gene encodes the α1 subunit of the calcium channel. The mutation of CACNA1S gene can cause hypokalemic periodic paralysis (HypoKPP) and maliglant hyperthermla synarome (MHS) in human beings. Current research on CACNA1S was mainly in human being and model animal, but rarely in livestock and poultry. In this study, Yorkshire pigs (23), Pietrain pigs (30), Jinhua pigs (115) and the second generation (126) of crossbred of Jinhua and Pietrein were used. Primers were designed according to the sequence of human CACNA1S gene and PCR was carried out using pig genome DNA.PCR products were sequenced and compared with that of human, and then single nucleotide polymorphisms (SNPs) were investigated by PCR-SSCP, while PCR-RFLP tests were performed to validate the mutations. Results indicated: (1) the 5211 bp DNA fragments of porcine CACNA1S gene were acquired (GenBank accession number: DQ767693 ) and the identity of the exon region was 82.6% between human and pig; (2) fifty-seven mutations were found within the cloned sequences, among which 24 were in exon region; (3) the results of PCR-RFLP were in accordance with that of PCR-SSCP. According to the EST of porcine CACNA1S gene published in GenBank (Bx914582, Bx666997), 8 of the 11 SNPs identified in the present study were consistent with the base difference between two EST fragments.

  10. Total Selenium and Selenium Species in Irrigation Drain Inflows to the Salton Sea, California, October 2008 and January 2009

    Science.gov (United States)

    May, Thomas W.; Walther, Michael J.; Saiki, Michael K.; Brumbaugh, William G.

    2009-01-01

    This report presents the results for two sampling periods (October 2008 and January 2009) during a 4-year monitoring program to characterize selenium concentrations in selected irrigation drains flowing into the Salton Sea, California. Total selenium, selenium species (dissolved selenite, selenate, organoselenium), and total suspended solids were determined in water samples. Total selenium also was determined in water column particulates and in sediment, detritus, and biota that included algae, plankton, midge larvae (family, Chironomidae), and two fish species (western mosquitofish, Gambusia affinis, and sailfin molly, Poecilia latipinna). In addition, sediments were analyzed for percent total organic carbon and particle size. Mean total selenium concentrations in water for both sampling periods ranged from 1.00 to 33.6 micrograms per liter, predominately as selenate, which is typical of waters where selenium is leached out of selenium-containing marine shales and associated soils under alkaline and oxidizing conditions. Total selenium concentrations (micrograms per gram dry weight) ranged as follows: algae, 1.52 to 8.26; plankton, 0.79 to 3.66; midges, 2.68 to 50.6; fish, 3.09 to 30.4; detritus, 1.78 to 58.0; and sediment, 0.42 to 10.0.

  11. GHG emissions and mitigation potential in Indian agriculture

    Science.gov (United States)

    Vetter, Sylvia; Feliciano, Diana; Sapkota, Tek; Hillier, Jon; Smith, Pete; Stirling, Clare

    2016-04-01

    India is one of the world's largest greenhouse gas (GHG) emitter, accounting for about 5% of global emissions with further increases expected in the future. The Government of India aims to reduce emission intensities by 20-25% by 2020 compared with the 2005 level. In a recent departure from past practice the reconvened Council on Climate Change stated that climate change in agriculture would include a component that would focus on reducing emissions in agriculture, particularly methane and nitrous oxide emissions. To develop recommendations for mitigation in agriculture in India, a baseline study is presented to analyse the GHG emissions from agriculture for current management (Directorate of Economics and Statistics of the government of India). This analysis is done for the two states Bihar and Haryana, which differ in their management and practises based on different climate and policies. This first analysis shows were the highest GHG emissions in agriculture is produced and were the highest mitigation potential might be. The GHG emissions and mitigation potential are calculated using the CCAFS Mitigation Option Tool (CCAFS-MOT) (https://ccafs.cgiar.org/mitigation-option-tool-agriculture#.VpTnWL826d4) with modifications for the special modelling. In a second step, stakeholder meetings provided a wide range of possible and definite scenarios (management, policy, technology, costs, etc.) for the future to mitigate emissions in agriculture as well as how to increase productivity. These information were used to create scenarios to give estimates for the mitigation potential in agriculture for India in 2020.

  12. ECH system and its application to long pulse discharge in large helical device

    Energy Technology Data Exchange (ETDEWEB)

    Shimozuma, T.; Kubo, S.; Sato, M.; Idei, H.; Takita, Y.; Ito, S.; Kobayashi, S.; Mizuno, Y.; Yoshimura, Y.; Ohkubo, K.; Funaba, H.; Inagaki, S.; Kobuchi, T.; Masuzaki, S.; Muto, S.; Shoji, M.; Suzuki, H.; Noda, N.; Nakamura, Y.; Kawahata, K.; Ohyabu, N.; Motojima, O

    2001-01-01

    We have developed and constructed an ECH system for the large helical device (LHD). The ECH system consists of 0.5 MW, 84 GHz range and 168 GHz gyrotrons, high voltage power supplies, long distance transmission lines, and in-vessel quasi-optical antennas. It has been improved step by step. At the third campaign of LHD experiments, three 84 GHz range (two 82.6 GHz and one 84 GHz) and three 168 GHz gyrotrons are operated and ECH power can be injected from four antennas vertically and two horizontally. This complicated system is remotely controlled and monitored by fully GUI (Graphical User Interface) control panels realized on PC via TCP (transmission control protocol) communication. Over 10000 shots of gyrotron power have been injected steadily into the LHD during the experimental campaigns on this system. One line of the system (84 GHz line) is specially prepared for the experiments of steady state plasma production. Using this line, plasma sustainment for 2 min was successfully achieved by only ECH power. Injected ECH power was 50 kW with 95% duty factor. The electron density and temperature of the sustained plasma are measured to be 0.3-0.5x10{sup 18} m{sup -3} and {approx}650 eV. Ion temperature measured by Doppler broadening of the impurity radiation line was kept constant at {approx}300 eV during RF injection.

  13. Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

    Directory of Open Access Journals (Sweden)

    Abdelrahman Esam G

    2012-12-01

    Full Text Available Abstract Background Iron deficiency anemia (IDA is a major health problem during pregnancy and it has adverse effects on the mother and the newborn. Red cell distribution width (RDW, which is a quantitative measure for red cell size variation (anisocytosis, is a predictor of IDA. Little is known regarding RDW and IDA during pregnancy. Methods A cross sectional study was conducted at the antenatal clinic of Khartoum Hospital, Sudan, to determine the performance of RDW in the diagnosis of IDA using serum ferritin as a gold standard. Results Among 194 pregnant women with a gestational period of 21.4 ± 6.5 weeks, 57 (29.4% had IDA according to serum ferritin levels (14.5. The sensitivity, specificity, positive predictive value, and negative predictive value of RDW where serum ferritin was the gold standard were 43.8% (95% CI: 31.4–57.0%, 73.7% (95% CI: 65.8–80.5%, 41.0% (95% CI: 29.2–53.6%, and 76.0% (95% CI: 68.1–82.6%, respectively. Conclusions In this study, we found that RDW has a poor performance in diagnosing IDA among pregnant women compared with serum ferritin as the gold standard. Virtual slides The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1721072967826303

  14. Independent and Combined Effects of Maternal Prepregnancy Body Mass Index and Gestational Weight Gain on Offspring Growth at 0-3 Years of Age.

    Science.gov (United States)

    Jin, Wen-Yuan; Lv, Yao; Bao, Yu; Tang, Li; Zhu, Zhi-Wei; Shao, Jie; Zhao, Zheng-Yan

    2016-01-01

    Background. The objective of this study was to investigate the independent and combined effects of maternal prepregnancy body mass index (BMI) and gestational weight gain (GWG) on offspring growth at 0-3 years old. Methods. A total of 826 pairs of nondiabetic mothers and their offspring were recruited in this study. Maternal information was abstracted from medical records and questionnaires. Offspring growth trajectories of weights and BMIs were depicted based on anthropometric measurements. Results. Offspring of mothers who were prepregnancy overweight/obese or obtained excessive GWGs continuously had greater weight and BMI Z-scores throughout the first 3 years of life. Children of prepregnancy overweight/obese mothers with excessive GWGs had a phenotype of higher weight and BMI Z-scores than those prepregnancy overweight/obese ones with nonexcessive GWGs from birth to 18 months. Maternal excessive GWGs increased offspring's risk of overweight/obesity at 12 months (AOR = 1.43, 95% CI: 1.03-2.00) and 24 months (AOR = 1.51, 95% CI: 1.02-2.25). Combination of excessive prepregnancy BMIs and GWGs was significantly associated with offspring's overweight/obesity at 30 months (AOR = 2.98, 95% CI: 1.36-6.53). Conclusions. Maternal prepregnancy overweight/obesity and excessive GWG are both significantly associated with rapid offspring growth from birth to 3 years old. Excessive GWGs strengthen the effects of high maternal prepregnancy BMIs on excessive offspring growth during their early life. PMID:27652262

  15. An Extraction Method of an Informative DOM Node from a Web Page by Using Layout Information

    Science.gov (United States)

    Tsuruta, Masanobu; Masuyama, Shigeru

    We propose an informative DOM node extraction method from a Web page for preprocessing of Web content mining. Our proposed method LM uses layout data of DOM nodes generated by a generic Web browser, and the learning set consists of hundreds of Web pages and the annotations of informative DOM nodes of those Web pages. Our method does not require large scale crawling of the whole Web site to which the target Web page belongs. We design LM so that it uses the information of the learning set more efficiently in comparison to the existing method that uses the same learning set. By experiments, we evaluate the methods obtained by combining one that consists of the method for extracting the informative DOM node both the proposed method and the existing methods, and the existing noise elimination methods: Heur removes advertisements and link-lists by some heuristics and CE removes the DOM nodes existing in the Web pages in the same Web site to which the target Web page belongs. Experimental results show that 1) LM outperforms other methods for extracting the informative DOM node, 2) the combination method (LM, {CE(10), Heur}) based on LM (precision: 0.755, recall: 0.826, F-measure: 0.746) outperforms other combination methods.

  16. Resultados de diferentes alternativas de manejo del riego superficial tecnificado en el cultivo de la papaya maradol roja plantada con marco extradenso

    Directory of Open Access Journals (Sweden)

    Ricardo Pérez Hernández

    2010-01-01

    Full Text Available El objetivo de este trabajo consistió en la realización de un estudio de diferentes manejos del riego por gravedad tecnificado, mediante evaluaciones de campo en el cultivo de referencia. El caudal de mejor comportamiento para el riego con flujo continuo con la variante de surcos abiertos de 130 m de longitud fue el de 1,56 L¿s-1, con eficiencia de aplicación 61,8%, eficiencia de almacenamiento 97% y distribución 82,6%. Las perdidas por escurrimiento superficial y percolación profunda fueron del 25% y 13% del volumen de agua aplicada, respectivamente. Para la variante de riego por surcos cerrados con dicho caudal, se obtuvieron incrementos en las eficiencias de aplicación y distribución, de 3,2 y 11,4% respectivamente, así como, un ahorro adicional total por concepto de los recursos agua y combustible de 232.8 peso¿año-1, respecto al riego por surcos abiertos. La variante de riego intermitente o por pulsos con 4 ciclos de tiempos variables, permitió lograr una eficiencia de aplicación del 85%, con un ahorro total de agua y combustible de 911.78 pesos anuales, asociado a una disminución del 24,37% del volumen total de agua suministrada por tonelada producida.

  17. Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) predictors of police officer problem behavior and collateral self-report test scores.

    Science.gov (United States)

    Tarescavage, Anthony M; Fischler, Gary L; Cappo, Bruce M; Hill, David O; Corey, David M; Ben-Porath, Yossef S

    2015-03-01

    The current study examined the predictive validity of Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008/2011) scores in police officer screenings. We utilized a sample of 712 police officer candidates (82.6% male) from 2 Midwestern police departments. The sample included 426 hired officers, most of whom had supervisor ratings of problem behaviors and human resource records of civilian complaints. With the full sample, we calculated zero-order correlations between MMPI-2-RF scale scores and scale scores from the California Psychological Inventory (Gough, 1956) and Inwald Personality Inventory (Inwald, 2006) by gender. In the hired sample, we correlated MMPI-2-RF scale scores with the outcome data for males only, owing to the relatively small number of hired women. Several scales demonstrated meaningful correlations with the criteria, particularly in the thought dysfunction and behavioral/externalizing dysfunction domains. After applying a correction for range restriction, the correlation coefficient magnitudes were generally in the moderate to large range. The practical implications of these findings were explored by means of risk ratio analyses, which indicated that officers who produced elevations at cutscores lower than the traditionally used 65 T-score level were as much as 10 times more likely than those scoring below the cutoff to exhibit problem behaviors. Overall, the results supported the validity of the MMPI-2-RF in this setting. Implications and limitations of this study are discussed. PMID:25383586

  18. Impacted Mandibular Third Molars: Review of Literature and a Proposal of a Combined Clinical and Radiological Classification

    Science.gov (United States)

    Santosh, P

    2015-01-01

    Tooth impaction is a pathological situation where a tooth fails to attain its normal functional position. Impacted third molars are commonly encountered in routine dental practice. The impaction rate is higher for third molars when compared with other teeth. The mandibular third molar impaction is said to be due to the inadequate space between the distal of the second mandibular molar and the anterior border of the ascending ramus of the mandible. Impacted teeth may remain asymptomatic or may be associated with various pathologies such as caries, pericoronitis, cysts, tumors, and also root resorption of the adjacent tooth. Even though various classifications exist in the literature, none of those address the combined clinical and radiologic assessment of the impacted third molar. Literature search using the advanced features of various databases such as PubMed, Scopus, Embase, Google Scholar, Directory of Open Access Journals and Cochrane electronic databases was carried out. Keywords like impaction, mandibular third molar, impacted mandibular third molar, complications, anatomy, inferior alveolar nerve injury, lingual nerve injury were used to search the databases. A total of 826 articles were screened, and 50 articles were included in the review which was obtained from 1980 to February 2015. In the present paper, the authors have proposed a classification based on clinical and radiological assessment of the impacted mandibular third molar. PMID:26229709

  19. Distribution of trace metal concentrations in paired cancerous and non-cancerous human stomach tissues

    Institute of Scientific and Technical Information of China (English)

    Mehmet Yaman; Gokce Kaya; Hayrettin Yekeler

    2007-01-01

    AIM: To assess whether trace metal concentrations (which influence metabolism as both essential and non-essential elements) are increased or decreased in cancerous tissues and to understand the precise role of these metals in carcinogenesis.METHODS: Concentrations of trace metals including Cd,Ni, Cu, Zn, Fe, Mg and Ca in both cancerous and noncancerous stomach tissue samples were determined by atomic absorption spectrometry (AAS). Tissue samples were digested using microwave energy. Slotted tube atom trap was used to improve the sensitivity of copper and cadmium in flame AAS determinations.RESULTS: From the obtained data in this study,the concentrations of nickel, copper and iron in the cancerous human stomach were found to be significantly higher than those in the non-cancerous tissues, by using t-test for the paired samples. Furthermore, the average calcium concentrations in the cancerous stomach tissue samples were found to be significantly lower than those in the non-cancerous stomach tissue samples by using t-test. Exceedingly high Zn concentrations (207-826 mg/kg) were found in two paired stomach tissue samples from both cancerous and non-cancerous parts.CONCLUSION: In contrast to the literature data for Cu and Fe, the concentrations of copper, iron and nickel in cancerous tissue samples are higher than those in the non-cancerous samples. Furthermore, the Ca levels are lower in cancerous tissue samples than in non-cancerous tissue samples.

  20. Awareness and Attitude of Physicians in Academia towards Human Stem Cell Research (HSCR and Related Policies in Rajasthan, India

    Directory of Open Access Journals (Sweden)

    Nitin K Joshi

    2015-12-01

    Full Text Available Introduction: In India, several science agencies are promoting Stem Cell Research (SCR. There is paucity of studies which document the perception of doctors about SCR, especially physicians in academia. This study was carried out to assess perception of physicians in academia towards Human Stem Cell Research (HSCR and related policies in India. Methods: We interviewed 200 doctors from three different government medical colleges of Rajasthan. A semi-structured questionnaire was used to discern their awareness, attitudes towards utilization of SCR and their knowledge of related international and ethical policy issues. Results: Though mostly 177 (96.2% physicians acknowledged the public health benefits of promoting stem cell research in India, but 166 (66.2% were not aware of the stem cell research policy of the Government of India and 111 (60.3% were not aware of the ICMR guidelines for Human Stem Cell Research in India. There was a strong desire among academic physicians 152 (82.6% to incorporate a course on SCR to the students in the near future. Discussion: Physicians in academia have views that SCR should be encouraged to treat clinical diseases and this technology should be brought into India in a big way. They seem to believe that one of the ways to promote the benefits of SCR would be to raise awareness by publishing success stories in widely read Indian Medical Journals, giving updated information regarding its uses in clinical practices and its inclusion as a part of the curricula for health professionals.

  1. Synthesis, characterization and application of electroless metal assisted silicon nanowire arrays

    Science.gov (United States)

    Sahoo, Sumanta Kumar; Marikani, Arumugam

    2015-12-01

    Vertically aligned silicon nanowire arrays (SiNWs) have been synthesized by electroless metal deposition process. The fabricated SiNWs have an average diameter of 75 nm and 3.5-4.0 μm length, as confirmed from scanning electron microscopy. A characteristic asymmetric peak broadening at 520 cm-1 from Raman spectroscopy was obtained for the SiNWs as compared to the bulk silicon crystal due to phonon confinement. The as-prepared SiNWs exhibit good electron field-emission properties with turn-on field of about 8.26 V μm-1 at a current density of 4.9 μA cm-2. The SiNWs was functionalized by coating with a thin gold metallic film for 60 s, and then used as bio-probe for the detection of bovine serum albumin (BSA) protein molecules. From the linear sweep voltammetry analysis, the Au coated SiNWs, exhibit linear response to the BSA analyte with increase in concentration. The minimum detection limit of the protein molecule was calculated of about 1.16 μM by the as-synthesized SiNWs probe.

  2. Study on Relationship Between Concentration of Complexes and Components of Coating

    Institute of Scientific and Technical Information of China (English)

    FAN Yun-ying; ZHANG Ying-jie; YANG Xian-wan; CHEN Zhen; ZHANG Jiang-hong; TU Zhen-mi

    2004-01-01

    Zn-Fe alloy coating was electrodeposited from acidic sulphate bath, and the relationship between real concentration of complexes ( [ ZnL + ] and [ FeL + ] ) in the bath and components of coating was studied. As the added 7H2O is increased from 40 g/L to 80 g/L, the ratio of iron complex to total complex increases from 50.02% to 66.23% , simultaneously the iron content in coating increases from 8.26% to 13.77%. As the added (NH4)2SO4 is increased from 40 g/L to 80 g/L, ratio of iron complex to total complex increases from 58.65% to 60. 37%, simultaneously the iron content in coating increases from 9.28% to 11.92%. The results indicate that, in the process of alloy deposition, variation of relative concentration of metallic complexes in the bath can lead to variation of components of coating proportionally. Accordingly, the variation of components of coating may be approximately deduced by calculating the variation of relative concentration of metallic complexes. Whereas, in order to judge the components of coating quantificationally, more research work need to be done on some other factors, such as the value of pH, current density, additives, etc.

  3. Clinical value of magnetic motor evoked potentials and electromyography in Graves disease%Graves病中磁运动诱发电位与肌电图的临床价值

    Institute of Scientific and Technical Information of China (English)

    林少达; 郭美云; 陈小华; 黄芷荷

    2005-01-01

    目的应用磁运动诱发电位(MEP)和肌电图(EMG)探讨Graves病(GD)神经肌肉受损临床价值.方法 GD病组46例行MEP和EMG检查;正常对照组50例行MEP检查,31例行EMG检查.结果 46例GD患者神经肌肉症状26例(56.5%),MEP异常38例(82.6%),EMG异常39例(84.8%);以MEP异常判断EMG异常敏感性87.2%,特异性89.5%;以EMG异常判断MEP异常敏感性89.5%,特异性87.2%.结论两种方法对CTM诊断异常率、敏感性和特异性相似;MEP主要对神经源性损害敏感,EMG主要对肌源性损害敏感,具互补性.

  4. Knowledge of electromyography (EMG) in patients undergoing EMG examinations.

    Science.gov (United States)

    Mondelli, Mauro; Aretini, Alessandro; Greco, Giuseppe

    2014-01-01

    The aim of this study was to evaluate knowledge of electromyography (EMG) in patients undergoing the procedure. In one year, 1,586 consecutive patients (mean age 56 years; 58.8% women) were admitted to two EMG labs to undergo EMG for the first time. The patients found to be "informed" about the how an EMG examination is performed and about the purpose of EMG numbered 448 (28.2%), while those found to be "informed" only about the manner of its execution or only about its purpose numbered 161 (10.2%) and 151 (9.5%), respectively. The remaining 826 (52.1%) patients had either no information, or the information they had was very poor or incorrect (this was particularly true if they had been consulting websites). Being "informed" was associated with level of education (high), type of referring physician (specialist) and with an appropriate referral diagnosis specified in the EMG request. The quality of patient information on EMG was found to be very poor and could be improved. Physicians referring patients for EMG examinations, especially general practitioners, should assume primary responsibility for patient education and counseling in this field.

  5. Determination of Antimony (III in Real Samples by Anodic Stripping Voltammetry Using a Mercury Film Screen-Printed Electrode

    Directory of Open Access Journals (Sweden)

    Olga Domínguez-Renedo

    2009-01-01

    Full Text Available This paper describes a procedure for the determination of antimony (III by differential pulse anodic stripping voltammetry using a mercury film screen-printed electrode as the working electrode. The procedure has been optimized using experimental design methodology. Under these conditions, in terms of Residual Standard Deviation (RSD, the repeatability (3.81 % and the reproducibility (5.07 % of the constructed electrodes were both analyzed. The detection limit for Sb (III was calculated at a value of 1.27×10–8 M. The linear range obtained was between 0.99 × 10–8 – 8.26 × 10–8 M. An analysis of possible effects due to the presence of foreign ions in the solution was performed and the procedure was successfully applied to the determination of antimony levels in pharmaceutical preparations and sea water samples.

  6. Serodiagnosis of human neurocysticercosis using antigenic components of Taenia solium metacestodes derived from the unbound fraction from jacalin affinity chromatography

    Directory of Open Access Journals (Sweden)

    Gleyce Alves Machado

    2013-05-01

    Full Text Available The aim of the present study was to analyse Taenia solium metacestode antigens that were derived from the unbound fraction of jacalin affinity chromatography and subsequent tert-octylphenoxy poly (oxyethylene ethanol Triton X-114 (TX-114 partitioning in the diagnosis of human neurocysticercosis (NCC. Immunoassays were designed to detect T. solium-specific IgG antibodies by ELISA and immunoblot. Serum samples were collected from 132 individuals who were categorised as follows: 40 had NCC, 62 presented Taenia spp or other parasitic diseases and 30 were healthy individuals. The jacalin-unbound (J unbound fraction presented higher sensitivity and specificity rates than the jacalin-bound fraction and only this fraction was subjected to subsequent TX-114 partitioning, resulting in detergent (DJ unbound and aqueous (AJ unbound fractions. The ELISA sensitivity and specificity were 85% and 84.8% for J unbound , 92.5% and 93.5% for DJ unbound and 82.5% and 82.6% for AJ unbound . By immunoblot, the DJ unbound fraction showed 100% sensitivity and specificity and only serum samples from patients with NCC recognised the 50-70 kDa T. solium-specific components. We conclude that the DJ unbound fraction can serve as a useful tool for the differential immunodiagnosis of NCC by immunoblot.

  7. Demography, clinical and laboratory features of systemic sclerosis in a Malaysian rheumatology centre.

    Science.gov (United States)

    Pagalavan, L; Ong, S G

    2007-06-01

    A six year retrospective study of the demography, clinical and laboratory features of patients with systemic sclerosis (SSc) was carried out in Selayang Hospital. There were 61 cases seen between January 2000 and December 2005. Of these, 55 (90.2%) were females and 6 (9.8%) were males. Twenty-eight (45.9%) were Malays, 24 (39.3%) were Chinese and 9 (14.8%) were Indians. The mean age of onset was 38.8 years. Thirty-nine (64.0%) had limited cutaneous SSc, 21 (34.4%) had diffuse cutaneous SSc and one had localized morphoea. Raynaud's phenomenon was present in 82.6%, telangiectasia in 45.9%, calcinosis in 11.5%, sclerodactyly in 83.6%, digital pitting scars in 42.6%, digital infarcts/ulcers/gangrene in 23.0%, arthralgia/arthritis in 49.2% and gastroesophageal reflux disease (GERD) in 47.5%. Forty-three (70.5%) patients had interstitial lung disease. Seven patients had associated myositis, 7 systemic lupus erythematosus and 2 rheumatoid arthritis. Three had two other connective tissue diseases. Antinuclear antibodies were positive in 83.6% and anti-Scl 70 antibodies in 34.4%. This study demonstrates that limited cutaneous SSc is more common and there is a high incidence of interstitial lung disease in our population. PMID:18705442

  8. Predicting outcomes in organophosphate poisoning based on APACHE II and modified APACHE II scores.

    Science.gov (United States)

    Eizadi-Mood, N; Saghaei, M; Jabalameli, M

    2007-07-01

    The aim of this study was to evaluate the scores of the Acute Physiology and Chronic Health Evaluation (APACHE) II and a modified APACHE II system (MAS), without parameters of biochemical tests; and to find prognostic value of individual elements of the APACHE II and MAS in predicting outcomes in organophosphate (OP) poisoning. Data were collected from 131 patients. The median (25th-75th percentiles) of APACHE II score for survivors without intubation were found to be lower than those of non survivors or survivors with intubation and ventilation, [4 (1-7); versus 17.5 (7.8-29), and 13.5 (7.8-16.3)]. Logistic regression analysis identified white blood cell (WBC), potassium, Glasgow coma scale (GCS), age and sodium in APACHE II; GCS and mean arterial pressure in MAS system as prognostically valuable. There was no statistically significance difference between APACHE II and MAS scores in terms of area under Receiver Operating Characteristic Curve [(0.902, 95% confidence interval: (0.837-0.947) for APACHE II), and (0.892, 95% confidence interval: (0.826-0.940) for MAS); P=0.74) to predict need for intubation. It is concluded usage of MAS facilitates the prognostication of the OP poisoned patients due to simplicity, less time-consuming and effectiveness in an emergency situation.

  9. A new design of foam spray nozzle used for precise dust control in underground coal mines

    Institute of Scientific and Technical Information of China (English)

    Han Fangwei; Wang Deming; Jiang Jiaxing; Zhu Xiaolong

    2016-01-01

    In order to improve the utilization rate of foam, an arc jet nozzle was designed for precise dust control. Through theoretical analysis, the different demands of foam were compared amongst arc jets, flat jets and full cone jets when the dust source was covered identically by foam. It is proved that foam consumption was least when an arc jet was used. Foam production capability of an arc jet nozzle under different con-ditions was investigated through experiments. The results show that with the gas liquid ratio (GLR) increasing, the spray state of an arc jet nozzle presents successively water jet, foam jet and mist. Under a reasonable working condition range of foam production and a fixed GLR, foam production quan-tity increases at first, and then decreases with the increase of liquid supply quantity. When the inner diameter of the nozzle is 14 mm, the best GLR is 30 and the optimum liquid supply quantity is 0.375 m3/h. The results of field experiments show that the total dust and respirable dust suppression effi-ciency of arc jet nozzles is 85.8%and 82.6%respectively, which are 1.39 and 1.37 times higher than the full cone nozzles and 1.20 and 1.19 times higher than the flat nozzles.

  10. Contraceptive Use and Associated Factors among Women Enrolling into HIV Care in Southwestern Uganda

    Directory of Open Access Journals (Sweden)

    Winnie Muyindike

    2012-01-01

    Full Text Available Background. Preventing unintended pregnancies among women living with HIV is an important component of prevention of mother-to-child HIV transmission (PMTCT, yet few data exist on contraceptive use among women entering HIV care. Methods. This was a retrospective study of electronic medical records from the initial HIV clinic visits of 826 sexually active, nonpregnant, 18–49-year old women in southwestern Uganda in 2009. We examined whether contraceptive use was associated with HIV status disclosure to one’s spouse. Results. The proportion reporting use of contraception was 27.8%. The most common method used was injectable hormones (51.7%, followed by condoms (29.6%, and oral contraceptives (8.7%. In multivariable analysis, the odds of contraceptive use were significantly higher among women reporting secondary education, higher income, three or more children, and younger age. There were no significant independent associations between contraceptive use and HIV status disclosure to spouse. Discussion. Contraceptive use among HIV-positive females enrolling into HIV care in southwestern Uganda was low. Our results suggest that increased emphasis should be given to increase the contraception uptake for all women especially those with lower education and income. HIV clinics may be prime sites for contraception education and service delivery integration.

  11. 60kV, 10Amp DC power supply multiple input control and monitoring provision for the operation of various high power RF generation systems

    International Nuclear Information System (INIS)

    A 60 kV, 10 A DC power supply is used for testing of high power RF and microwave tubes e.g. Klystron, Gyrotron. Two 500 kW, 3.7 GHz klystrons, and one 82.6 GHz Gyrotron are located in SST1 Hall where as 200 kW; 28 GHz Gyrotron is located in Aditya Hall. The same power supply is required to operate, control and monitor various systems at different locations with easy change over from one system to other as per experimental requirements. An off line, control change over system, is designed to accomplish the above requirements, with control panels installed at desired different locations. The input (0 to 11 kV) A.C. voltage to power supply is given from a motorized voltage variation system (VVS). The control panels provide indication of A.C. input voltage to power supply from 11 kV potential transformers of VVS. In addition, the control panel is provided with 11 kV circuit breaker status indication and control i.e. Emergency OFF switch. The control panels are designed and developed indigenously which are successfully installed and are in continuous use for the safe and easy operation of different high power rf systems from the same DC power supply. The paper presents the design of the controls, monitoring and indications. Safety aspects of the system are also highlighted.

  12. 210Po and 210Pb Activity Concentrations in Cigarettes Produced in Vietnam and Their Estimated Dose Contribution Due to Smoking

    Science.gov (United States)

    Tran, Thuy-Ngan N.; Le, Cong-Hao; Chau, Van-Tao

    Smoking cigarettes contributes significantly to the increase of radiation in human body because 210Po and 210Pb exist relatively high in tobacco leaves. Therefore, these two radioisotopes in eighteen of the most frequently sold cigarette brands produced in Vietnam were examined in this study. 210Po was determined by alpha spectroscopy using a passivated implanted planar silicon (PIPS) detector after a procedure including radiochemical separation and spontaneous deposition of polonium on a copper disc (the deposition efficiency of 210Po on a copper disc was approximately 94%). Sequentially, 210Pb was determined through the ingrowth of 210Po after storing the sample solutions for approximately six months. The activity concentrations of 210Po in cigarettes ranged from 13.8 to 82.6 mBq/cigarette (the mean value was 26.4 mBq/cigarette) and the activity concentrations of 210Pb in cigarettes ranged from 13.9 to 78.8 mBq/cigarette (the mean value was 25.8 mBq/cigarette). The annual committed effective dose for smokers who smoke one pack per day was also estimated to be 295.4 µSv/year (223.0 µSv/year and 72.4 µSv/year from 210Po and 210Pb, respectively). These indicated that smoking increased the risk of developing lung cancer was approximately 60 times greater for smokers than for non-smokers.

  13. Continuous flow membrane-less air cathode microbial fuel cell with spunbonded olefin diffusion layer.

    Science.gov (United States)

    Tugtas, Adile Evren; Cavdar, Pelin; Calli, Baris

    2011-11-01

    The power production performance of a membrane-less air-cathode microbial fuel cell was evaluated for 53 days. Anode and cathode electrodes and the micro-fiber cloth separator were configured by sandwiching the separator between two electrodes. In addition, the air-facing side of the cathode was covered with a spunbonded olefin sheet instead of polytetrafluoroethylene (PTFE) coating to control oxygen diffusion and water loss. The configuration resulted in a low resistance of about 4Ω and a maximum power density of 750 mW/m2. However, as a result of a gradual decrease in the cathode potential, maximum power density decreased to 280 mW/m2. The declining power output was attributed to loss of platinum catalyst (8.26%) and biomass growth (38.44%) on the cathode. Coulombic efficiencies over 55% and no water leakage showed that the spunbonded olefin sheet covering the air-facing side of the cathode can be a cost-effective alternative to PTFE coating.

  14. Identification of RAPD and SCAR markers associated with yield traits in the Indian tropical tasar silkworm Antheraea mylitta drury

    Directory of Open Access Journals (Sweden)

    Suhrid R. Dutta

    2012-01-01

    Full Text Available The tropical tasar silkworm, Antheraea mylitta, is a semi-domesticated vanya silk-producing insect of high economic importance. To date, no molecular marker associated with cocoon and shell weights has been identified in this species. In this report, we identified a randomly amplified polymorphic DNA (RAPD marker and examined its inheritance, and also developed a stable diagnostic sequence-characterized amplified region (SCAR marker. Silkworms were divided into groups with high (HCSW and low (LCSW cocoon and shell weights, and the F2 progeny of a cross between these two groups were obtained. DNA from these silkworms was screened by PCR using 34 random primers and the resulting RAPD fragments were used for cluster analysis and discriminant function analysis (DFA. The clustering pattern in a UPGMA-based dendogram and DFA clearly distinguished the HCSW and LCSW groups. Multiple regression analysis identified five markers associated with cocoon and shell weights. The marker OPW16(905 bp showed the most significant association with cocoon and shell weights, and its inheritance was confirmed in F2 progeny. Cloning and sequencing of this 905 bp fragment showed 88% identity between its 134 nucleotides and the Bmc-1/Yamato-like retroposon of A. mylitta. This marker was further converted into a diagnostic SCAR marker (SCOPW 16(826 bp. The SCAR marker developed here may be useful in identifying the right parental stock of tasar silkworms for high cocoon and shell weights in breeding programs designed to enhance the productivity of tasar silk.

  15. Absolute quantification of swine brain glutamate compounds concentration using MR spectroscopy and LCModel after nasal spraying butorphanol tartrate

    International Nuclear Information System (INIS)

    Objective: The purpose of this study was to investigate whether the central nervous system (CNS) analgesics affect the metabolites of swine brain by nasal spraying. Methods: Single voxel proton magnetic resonance spectroscopy (1H-MRS) was performed on 9 swine. The data were post-processed using LCModel software. Results: Before nasal spraying butorphanol tartrate, the mean Glutamate compounds (Glxs) concentration was (9.276±0.542) mmol/kg. After nasal spraying, the mean Glx concentration was (7.283±0.540) mmol/kg. Using paired sample t-test we found that swine brain ax level was significantly decreased after using nasal spray analgesic (t=2.826, P=0.022). However, there were no significant differences in mean NAA and Choline (Cho) concentrations before and after nasal spraying [(6.094±0.384) mmol/kg vs. (5.530±0.346) mmol/kg (t=1.270, P=0.240) and (1.547±0.114) mmol/kg vs. (1.255±0.079) mmol/kg (t=1.800, P=0.110), respectively). Conclusion: Our results imply that Glxs are nociceptive neurotransmitters and play an important role in the analgesia. (authors)

  16. Design and testing of a uniformly solar energy TIR-R concentration lenses for HCPV systems.

    Science.gov (United States)

    Shen, S C; Chang, S J; Yeh, C Y; Teng, P C

    2013-11-01

    In this paper, total internal reflection-refraction (TIR-R) concentration (U-TIR-R-C) lens module were designed for uniformity using the energy configuration method to eliminate hot spots on the surface of solar cell and increase conversion efficiency. The design of most current solar concentrators emphasizes the high-power concentration of solar energy, however neglects the conversion inefficiency resulting from hot spots generated by uneven distributions of solar energy concentrated on solar cells. The energy configuration method proposed in this study employs the concept of ray tracing to uniformly distribute solar energy to solar cells through a U-TIR-R-C lens module. The U-TIR-R-C lens module adopted in this study possessed a 76-mm diameter, a 41-mm thickness, concentration ratio of 1134 Suns, 82.6% optical efficiency, and 94.7% uniformity. The experiments demonstrated that the U-TIR-R-C lens module reduced the core temperature of the solar cell from 108 °C to 69 °C and the overall temperature difference from 45 °C to 10 °C, and effectively relative increased the conversion efficiency by approximately 3.8%. Therefore, the U-TIR-R-C lens module designed can effectively concentrate a large area of sunlight onto a small solar cell, and the concentrated solar energy can be evenly distributed in the solar cell to achieve uniform irradiance and effectively eliminate hot spots.

  17. Estimation of Kinetic Parameters for Enzyme Catalysed Batch Bioreactor for the Production of Ethanol from Corn

    Directory of Open Access Journals (Sweden)

    Z. R. Yelebe

    2014-03-01

    Full Text Available This paper addresses the challenge of estimating various kinetic parameters for the design of an optimized enzyme catalysed batch bioreactor of high efficiency and yield. Mathematical models were developed to describe the batch reaction time in relation to the substrate, enzyme and product concentration. The results obtained from the plots generated were: 35.50gmol/l.hr for the velocity of reaction of the enzymes (Vmax, 0.10049hr-1 for the maximum specific growth rate (µmax 826.45gmol/l for the Michaelis-Menten constant (Km, 0.005402577 for maintenance coefficient (Ms, 10.104kgCx/kgCs for yield of cell weight per unit weight of substrate (Ycx/CS, 0.05436kgCp/kgCs for yield of product weight per unit weight of substrate utilized (Ycp/CS and 0.01416 for endogenous decay coefficient (Kd for the design of the batch biochemical reactor. Hence, they are useful parameters for predicting the most appropriate batch reaction conditions and the efficiency of the bioreactor. The mathematical model predictions showed that it can be considered as a good complimentary tool to real system since the simulation results of the mathematical model agrees with experimental data reported in literature.

  18. AB212. Clinical study on the treatment of lifelong premature ejaculation with Paroxetine hydrochloride and tamsulosin

    Science.gov (United States)

    Li, Yan-Feng; Zhang, Chao; Li, Bo-Jun

    2016-01-01

    Objective There are quite a few researches about SSRIs and alpha-receptor blockers on the treatment of premature ejaculation (PE), but few researches focus on the combination use of them. In this study, we evaluate the efficacy and safety of combine and alone use of paroxetine hydrochloride and tamsulosin on the treatment of lifelong PE. Methods 352 cases of men with 18–65 years of age, a history of lifelong PE and an intra-vaginal ejaculation latency time (IELT) premature ejaculation profile (PEP), the adverse events (AEs) and vital sign measurements were recorded at each visit. All the data were statistically analyzed. Results The reliable data from 322 patients were achieved. The geometric mean IELT in group A was significantly increased from 1.15 to 8.13 min after treatment (Pejaculation, satisfaction with sexual intercourse, ejaculation-related personal distress, and ejaculation-related interpersonal difficulty were significantly improved in all groups after treatment (P<0.001). The mean PEP scores in group C have more significant improvements than that in group A and B (P<0.01). The prevalence of AEs in group A, B, C were 9.26% (10 cases), 3.81% (4 cases) and 8.26% (9 cases), respectively. Conclusions Paroxetine hydrochloride combined with tamsulosin produce more better therapeutic effects than use them separately. It could be a priority for the treatment of lifelong PE.

  19. Molecular identification of Greek olive (Olea europaea) cultivars based on microsatellite loci.

    Science.gov (United States)

    Roubos, K; Moustakas, M; Aravanopoulos, F A

    2010-01-01

    Olea europaea is one of the oldest species of domesticated trees. We used microsatellite markers for fingerprinting and for evaluation of genetic similarity and structure of 26 Greek olive cultivars, which cover most of the olive cultivation regions of Greece, including previously undescribed denominations from northern Greece. Eighty-one alleles were revealed with six SSR loci that were selected as most informative of 10 SSR primers that were initially investigated. The number of alleles per locus varied from 7 to 20 (mean, 13.5). Heterozygosity ranged from 0.240 at locus DCA-3 to 0.826 at locus UDO99-9, with a mean value of 0.600. Analysis of 104 trees representing 26 denominations (four trees per denomination) revealed 26 distinct SSR profiles, indicating 26 olive cultivars; no intracultivar variability was observed. Genetic and geographic distances were not significantly correlated, based on the Mantel test. These SSR loci allowed unequivocal identification of all the cultivars and will be useful for future breeding and olive germplasm management efforts.

  20. 高温平菇菌株评价%The Evaluation of Thermotolerant Pleurotus Ostreatus Strains

    Institute of Scientific and Technical Information of China (English)

    应正河; 林兴生; 余应瑞; 江晓凌; 林衍铨

    2009-01-01

    高温平菇主要在夏季栽培,为了获得高质量的菌株,对13个高温平菇菌株的茵丝最适生长温度、农艺性状进行测定与分析,结果表明11个茵株的最适生长温度是30℃,茵丝生长速度为0.36~1.07 cm/天,Pnl达到最大值1.07 cm/天.生物学效率为82.6%~117.4%,其中7个菌株的生物学效率在100%以上.通过比较试验,Pnl是具有在高温下菌丝生长速度最快、生育期短、生物学效率高和菇形好的优良菌株,适合在福建省东南热带地区推广的菌株.

  1. Toxicity of three oil spill remediation techniques to the Australian bass Macquaria novemaculeata.

    Science.gov (United States)

    Cohen, A M; Nugegoda, D

    2000-10-01

    Australian bass, Macquaria novemaculeata, were exposed to the water accommodated fraction (WAF) of Bass Strait crude oil, dispersed crude oil, burnt crude oil, and 4-chlorophenol. The WAF of dispersed crude oil was the most toxic treatment with 96-h LC(50) values of 7. 15% (7.94% upper and 6.42% lower 95% CI) and 7.45% (8.26% upper and 6.71% lower 95% CI). The WAF of crude oil was less toxic, with 96-h LC(50) values of 43.72% (49.21% upper and 38.87% lower 95% CI) and 45.87% (51.51% upper and 40.97% lower 95% CI). The WAF of burnt crude oil was the least toxic treatment with 96-h LC(50) values of 49.81% (63.33% upper and 39.44% lower 95% CI) and 47.28% (59.72% upper and 37.62% lower 95% CI). Sublethal toxicity of the crude oil WAF and burnt crude oil WAF was observed at dilutions seven to eight times less than in the dispersed crude oil WAF.

  2. Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice.

    Directory of Open Access Journals (Sweden)

    Haniyeh Ghaffari-Nazari

    Full Text Available Peptide-based vaccines are attractive approaches for cancer immunotherapy; but the success of these vaccines in clinical trials have been limited. Our goal is to improve immune responses and anti-tumor effects against a synthetic, multi-epitope, long peptide from rat Her2/neu (rHer2/neu using the help of CD4+ T cells and appropriate adjuvant in a mouse tumor model. Female BALB/c mice were vaccinated with P5+435 multi-epitope long peptide that presents epitopes for cytotoxic T lymphocytes (CTL in combination with a universal Pan DR epitope (PADRE or CpG-oligodeoxynucleotides (CpG-ODNs as a Toll-like receptor agonist adjuvant. The results show that vaccination with the multi-epitope long peptide in combination with the PADRE peptide and CpG-ODN induced expansion of subpopulations of CD4+ and CD8+ cells producing IFN-γ, the average tumor size in the vaccinated mice was less than that of the other groups, and tumor growth was inhibited in 40% of the mice in the vaccinated group. The mean survival time was 82.6 ± 1.25 days in mice vaccinated with P5+435 + CpG+ PADRE. Our results demonstrate that inclusion of PADRE and CpG with the peptide vaccine enhanced significant tumor specific-immune responses in vaccinated mice.

  3. STUDY OF CLINICAL AND HISTOPATHOLOGICAL PRESENTATION OF OVARIAN MASSES IN TEACHING HOSPITAL

    Directory of Open Access Journals (Sweden)

    Shobha

    2016-02-01

    Full Text Available OBJECTIVE To study the clinical and histopathological presentation of ovarian masses. METHOD Hospital based retrospective study done on 200 patients in the Department of Gynaecology, Gandhi Hospital, Secunderabad, who are clinically and sonologically diagnosed to have ovarian masses during the period of January 2014 to September 2015. RESULTS The prevalence of ovarian masses in our study was 0.6%. Among the 200 cases, 60.5% were neoplastic and 39.5% were non-neoplastic. Among neoplasms 90% were benign, 8.26% malignant and 1.65% borderline. Serous cystadenoma was the commonest benign tumor (55% followed by Mucinous (27.5% and Dermoid (15.5%. Most common malignant ovarian tumor was Serous cystadenocarcinoma (60%. CONCLUSION Ovarian neoplasms have twice the incidence of non-neoplasms. Maximum incidence of malignancy is in between 40-49 years of age group. Non-specific abdominal symptoms should be given more importance, as it may be the only clue to the underlying malignancy. So effective clinical, biochemical and radiological diagnosis helps in early intervention to increase the survival rates in malignancy. Sixty million people are affected with glaucoma worldwide and more than 20 million have PACG. Of these more than 5 million with PACG are blind, which is twice more than POAG. Early detection and timely treatment with Nd:YAG laser iridotomy and associated complications determine visual outcome.

  4. 5-ALA Fluorescence Image Guided Resection of Glioblastoma Multiforme: A Meta-Analysis of the Literature

    Directory of Open Access Journals (Sweden)

    Samy Eljamel

    2015-05-01

    Full Text Available Background: Glioblastoma multiforme (GBM is one of the most deadly cancers in humans. Despite recent advances in anti-cancer therapies, most patients with GBM die from local disease progression. Fluorescence image guided surgical resection (FIGR was recently advocated to enhance local control of GBM. This is meta-analyses of 5-aminolevulinic (5-ALA induced FIGR. Materials: Review of the literature produced 503 potential publications; only 20 of these fulfilled the inclusion criteria of this analysis, including a total of 565 patients treated with 5-ALA-FIGR reporting on its outcomes and 800 histological samples reporting 5-ALA-FIGR sensitivity and specificity. Results: The mean gross total resection (GTR rate was 75.4% (95% CI: 67.4–83.5, p < 0.001. The mean time to tumor progression (TTP was 8.1 months (95% CI: 4.7–12, p < 0.001. The mean overall survival gain reported was 6.2 months (95% CI: −1–13, p < 0.001. The specificity was 88.9% (95% CI: 83.9–93.9, p < 0.001 and the sensitivity was 82.6% (95% CI: 73.9–91.9, p < 0.001. Conclusion: 5-ALA-FIGR in GBM is highly sensitive and specific, and imparts significant benefits to patients in terms of improved GTR and TTP.

  5. Comparison of eight degree-days estimation methods in four agroecological regions in Colombia

    Directory of Open Access Journals (Sweden)

    Daniel Rodríguez Caicedo

    2012-01-01

    Full Text Available Eight methods were used to estimate degree-days in four Colombian localities. Four methods have been previously proposed in literature: Simple Sine, Double Sine, Simple Triangle, and Double Triangle methods. The other four methods are proposed in this research: Simple Logistic, Double Logistic, Simple Normal, and Double Normal. The estimation of the degree-days through hourly temperature values was used as the reference standard method, and the four localities from where the temperature values were taken were the municipalities of Cajicá (Cundinamarca, Santa Elena (Antioquia, Carepa (Urabá Antioqueño, and Ciudad Bolivar (Zona cafetera Antioqueña. Degree-days obtained by all methods under study were compared through linear regression to those obtained by the reference standard method. There were differences in the correlation of each method to the reference when compared within each region and among regions. The Simple Logistic and Double Logistic methods showed the best performance with acceptable R² values and considerably lower bias than the other methods. The poorest fit was found in Cajicá, where the average R² was 0.571. For the regions of Santa Elena and Carepa, the average R² was 0.756 and 0.733. The best fit was found in Ciudad Bolivar, with an average R² of 0.826.

  6. Experimental study of solvent-based emulsion injection to enhance heavy oil recovery in Alaska North Slope area

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, F.; Mamora, D. [Texas A and M Univ., College Station, TX (United States)

    2010-07-01

    This study examined the feasibility of using a chemical enhanced oil recovery method to overcome some of the technical challenges associated with thermal recovery in the Alaska North Slope (ANS). This paper described the second stage research of an experimental study on nano-particle and surfactant-stabilized solvent-based emulsions for the ANS area. Four successful core flood experiments were performed using heavy ANS oil. The runs included water flooding followed by emulsion flooding; and pure emulsion injection core flooding. The injection rate and core flooding temperature remained constant and only 1 PV micro-emulsion was injected after breakthrough under water flooding or emulsion flooding. Oil recovery increased by 26.4 percent from 56.2 percent original oil in place (OOIP) with waterflooding to 82.6 percent OOIP with injection of emulsion following water flooding. Oil recovery was slightly higher with pure emulsion flooding, at 85.8 percent OOIP. The study showed that low permeability generally resulted in a higher shear rate, which is favourable for in-situ emulsification and higher displacement efficiency. 11 refs., 4 tabs., 20 figs.

  7. Assembly and electroanalytical performance of Prussian blue/polypyrrole composite nanoparticles synthesized by the reverse micelle method

    Energy Technology Data Exchange (ETDEWEB)

    Miao Yuqing; Liu Jiwei, E-mail: biosensors@zjnu.c [Laboratory of Biocatalysis and Biosensor, Institute of Physical Chemistry, Zhejiang Normal University, Jinhua 321004 (China)

    2009-04-15

    We report on the characterization, assembly and electroanalytical performance of Prussian blue/polypyrrole (PBPPy) composite nanoparticles synthesized by the reverse micelle method. Scanning electron microscopy suggests the formation of nanosized PBPPy particles with diameters between 40 and 50 nm. Optical absorption confirms that the particles are composed of Prussian blue (PB) and polypyrrole. PB and PBPPy nanoparticles were anchored onto the surface of cysteine-modified Au electrodes. Cyclic voltammetry experiments show that PB- or PBPPy-modified electrodes exhibit intrinsic electrochemical properties and a high electrocatalytic activity towards H{sub 2}O{sub 2}. PBPPy-modified electrodes exhibit a higher sensitivity to H{sub 2}O{sub 2} than PB-modified electrodes. A linear calibration curve in the concentration range 0.99 {mu}M-8.26 mM H{sub 2}O{sub 2} is constructed with a detection limit of 0.23 {mu}M at a signal-to-noise ratio of 3. Excellent stability is observed for PBPPy-composite-nanoparticle-modified electrodes even in a pH 6 phosphate buffer solution with a high H{sub 2}O{sub 2} concentration (0.99 mM). Glutaraldehyde and Nafion were also employed to immobilize glucose oxidase for the development of PBPPy-based biosensors. The results show that PBPPy composite nanoparticles can be used to develop oxidase-based biosensors.

  8. Protective immune barrier against hepatitis B is needed in individuals born before infant HBV vaccination program in China.

    Science.gov (United States)

    Yang, Shigui; Yu, Chengbo; Chen, Ping; Deng, Min; Cao, Qing; Li, Yiping; Ren, Jingjing; Xu, Kaijin; Yao, Jun; Xie, Tiansheng; Wang, Chencheng; Cui, Yuanxia; Ding, Cheng; Tian, Guo; Wang, Bing; Zhang, Xiaoyan; Ruan, Bing; Li, Lanjuan

    2015-01-01

    The hepatitis B prevalence rate in adults is still at a high to intermediate level in China. Our purpose was to explore the incidence rate and protective immune barrier against hepatitis B in adults in China. A sample of 317961 participants was multi-screened for hepatitis B surface antigens (HBsAg) in a large-scale cohort of the National Hepatitis B Demonstration Project. A total of 5401 persons were newly-infected, representing an incidence rate of 0.81 (95% CI: 0.77-0.85) per 100 person-years after adjusted by gender and age. History of acquired immune deficiency syndrome, birth prior to 1992, coastal residence, family history of HBV, and migrant worker status were significantly associated with higher incidence, while HBV vaccination and greater exercise with lower incidence. The hepatitis B surface antibody (HBsAb) positive rate was negatively correlated with the incidence rate of hepatitis B (r = -0.826). Linear fitting yielded an incidence rate of 1.23 plus 0.02 multiplied by HBsAb positive rate. The study firstly identified the HBsAg incidence rate, which was reduced to 0.1 per 100 person-years after vaccination coverage of about 64%. The protective immune barrier against hepatitis B needs to be established in individuals born prior to the advent of infant HBV vaccination. PMID:26655735

  9. METHANOLYSIS AND ETHANOLYSIS OF ANIMAL FATS: A COMPARATIVE STUDY OF THE INFLUENCE OF ALCOHOLS

    Directory of Open Access Journals (Sweden)

    MANUEL GARCÍA

    2011-03-01

    Full Text Available Biodiesel from animal fats with methanol and ethanol was produced in the presence of sodium methoxide and sodium ethoxide as catalysts. Two samples of pork fats and one natural beef tallow were directly transesterified with a good final product yield: 87.7, 86.7 and 86.3% for methanolysis, and 78.4, 82.6 and 82.7% for ethanolysis, respectively. Methyl ester content was also determined, being higher than 96.5 mass% for all the samples prepared. The presence of natural C17:0 in animal fats makes it necessary to correct the method pro¬posed in the standard EN 14103 (2003. Biodiesel density at 15 C of the samples was between 870 and 876 kg/m3, within the acceptance range of standard EN 14214, and the dynamic viscosity at 40 °C of the produced biodiesels was in the range of 4.5 to 5.16 mm2/s, also fulfilling requirements of EN 14214 standard. The iodine value is much lower than the superior limit established by EN 14214 standard but oxidation stability (OSI is lower than the required limit, 6 h, of the standard, which can be attributed to the lack of natural antioxidants in tallows.

  10. Rotavirus infection in a tertiary hospital: laboratory diagnosis and impact of immunization on pediatric hospitalization

    Directory of Open Access Journals (Sweden)

    Luciane Aparecida Pereira

    2011-06-01

    Full Text Available BACKGROUND AND OBJECTIVES: Rotavirus (RV is the main etiological agent of diarrhea in childhood; its laboratory diagnosis is crucial to guide the clinical management and prevention of its spread. RV immunization was introduced in Brazilian 6-month-old children in 2006. The present study was aimed to evaluate three methodologies used for human RV detection in stool samples obtained from patients hospitalized due to gastroenteritis in a teaching hospital and report the impact of RV immunization in hospitalization by diarrhea. METHODS: 293 stool samples collected in the 2001-2008 period were analyzed by enzyme immunoassay (EIA, latex agglutination (LA and polyacrylamide gel electrophoresis (PAGE. RESULTS: Rotavirus was detected in 34.8% of samples by LA assay, 28.3% of samples by EIA assay and in 25.6% of samples by PAGE assay. Considering the PAGE method as gold standard, the sensitivity, specificity and accuracy of EIA were 94.6%, 94.4% and 94.5%, and to LA were 82.6%, 81.6% and 81.9%, respectively. CONCLUSION: These results indicate that antigen detection by EIA is a rapid, sensitive and specific method, and could be used in large-scale applications for screening stool samples suspected of RV infection. This study showed decreased incidence of RV infection in hospitalized children prior to the implementation of the national immunization program against RV.

  11. Some functional properties of composite material based on scrap tires

    Science.gov (United States)

    Plesuma, Renate; Malers, Laimonis

    2013-09-01

    The utilization of scrap tires still obtains a remarkable importance from the aspect of unloading the environment from non-degradable waste [1]. One of the most prospective ways for scrap tires reuse is a production of composite materials [2] This research must be considered as a continuation of previous investigations [3, 4]. It is devoted to the clarification of some functional properties, which are considered important for the view of practical applications, of the composite material. Some functional properties of the material were investigated, for instance, the compressive stress at different extent of deformation of sample (till 67% of initial thickness) (LVS EN 826) [5] and the resistance to UV radiation (modified method based on LVS EN 14836) [6]. Experiments were realized on the purposefully selected samples. The results were evaluated in the correlation with potential changes of Shore C hardness (Shore scale, ISO 7619-1, ISO 868) [7, 8]. The results showed noticeable resistance of the composite material against the mechanical influence and ultraviolet (UV) radiation. The correlation with the composition of the material, activity of binder, definite technological parameters, and the conditions supported during the production, were determined. It was estimated that selected properties and characteristics of the material are strongly dependent from the composition and technological parameters used in production of the composite material, and from the size of rubber crumb. Obtained results show possibility to attain desirable changes in the composite material properties by changing both the composition and technological parameters of examined material.

  12. Simultaneous laparoscopic excision for rectal carcinoma and synchronous hepatic metastasis

    Institute of Scientific and Technical Information of China (English)

    CHEN Kai-yun; XIANG Guo-an; WANG Han-ning; XIAO Fang-lian

    2011-01-01

    Background Rectal carcinoma patients are often accompanied by hepatic metastasis. The aim of this study was to evaluate the therapeutic efficacy of simultaneous laparoscopic excision for rectal carcinoma with synchronous hepatic metastasis.Methods A total of 41 patients with rectal carcinoma and synchronous hepatic metastasis detected by CT scan were included in this study. Among them, 23 patients underwent laparoscopic surgery and 18 patients underwent traditional open surgery to simultaneously remove the rectal tumor and hepatic metastasis lesions. All patients received postoperative adjuvant chemotherapy. All the patients were followed up from 36 to 72 months (mean 45.3 months).Results All the operations were performed successfully and no patient was turned to open surgery in laparoscopic group. The mean blood loss, the mean postoperative hospital stay, the mean blood transfusion and the mean intestinal functional recovery time showed a significant difference between the two groups (P<0.05). The 1-, 3- and 5-year survival rates were 82.6%, 43.5% and 8.6% in the laparoscopic group, without significant difference compared with the open group (77.8%, 38.9% and 0) (P>0.05).Conclusions Simultaneous laparoscopic excision for rectal carcinoma and synchronous hepatic metastasis is safe and effective with similar survival achieved by the traditional open abdominal surgery.

  13. Cystic and alveolar echinococcosis: an epidemiological survey in a Tibetan population in southeast Qinghai, China.

    Science.gov (United States)

    Yu, Sen-Hai; Wang, Hu; Wu, Xian-Hong; Ma, Xiao; Liu, Pei-Yun; Liu, Yu-Fang; Zhao, Yan-Mei; Morishima, Yasuyuki; Kawanaka, Masanori

    2008-05-01

    An epidemiological investigation on echinococcosis was made in Jiuzhi County of Qinghai Province, western China. Ultrasonography and an indirect hemagglutination test revealed a morbidity of 8.0% (124/1,549) and a seroprevalence of 25.8% (287/1,113), respectively, in the Tibetan population. The morbidity in herdsmen (16.6%) and Buddhist priests (15%) was significantly higher than that in other occupation groups (3.2%), and it was higher in females (9.8%) than in males (6.2%). The ultrasound images showed a coexistence of cystic echinococcosis (CE) and alveolar echinococcosis (AE), occupying 69 and 31% of the cases, respectively. An Echinococcus Western blot assay was performed as a serological backup test for differentiating CE and AE. The assay revealed that serum samples from most cases with a positive AE image showed a specific antibody against antigen bands at 16/18 kDa. Autopsy proved that 9 out of 12 stray dogs were infected with Echinococcus granulosus (n = 8) and E. multilocularis (n = 1). Inspection at the abattoirs demonstrated a hydatid rate of 78.5% in yaks and 82.6% in sheep. The data indicate that Jiuzhi County is an important endemic area for both CE and AE, in both human and animal populations. PMID:18503183

  14. NaI detector nonlinearity for PGNAA applications

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, Robin P.; Mayo, Charles W

    1999-08-01

    The nonlinearity of a 6''x6'' NaI detector used for PGNAA has been measured. The prompt {gamma}-rays from pure element samples mixed with graphite were used for this determination in the range from 1.712 to 10.829 MeV and {gamma}-rays from radioisotope sources were used in the range from 0.356 to 1.333 MeV. A surprising result is that the pulse height per unit absorbed energy is slightly higher from single escape as opposed to full energy peaks. One explanation for this is that the light production efficiency for positrons may be different than that for electrons. By interpolation a value for the coincidence spectral full energy peak exhibited by NaI detectors that are neutron activated is obtained. The value reported is 6.885 MeV which is slightly higher than the cross section weighted value of 6.834 MeV. (The reported S{sub N} values for I and Na are 6.826 and 6.959 MeV, respectively.)

  15. NaI detector nonlinearity for PGNAA applications

    CERN Document Server

    Gardner, R P

    1999-01-01

    The nonlinearity of a 6''x6'' NaI detector used for PGNAA has been measured. The prompt gamma-rays from pure element samples mixed with graphite were used for this determination in the range from 1.712 to 10.829 MeV and gamma-rays from radioisotope sources were used in the range from 0.356 to 1.333 MeV. A surprising result is that the pulse height per unit absorbed energy is slightly higher from single escape as opposed to full energy peaks. One explanation for this is that the light production efficiency for positrons may be different than that for electrons. By interpolation a value for the coincidence spectral full energy peak exhibited by NaI detectors that are neutron activated is obtained. The value reported is 6.885 MeV which is slightly higher than the cross section weighted value of 6.834 MeV. (The reported S sub N values for I and Na are 6.826 and 6.959 MeV, respectively.)

  16. Rates of oxygen consumption and tolerance of hypoxia and desiccation in Chinese black sleeper (Bostrichthys sinensis) and mudskipper (Boleophthalmus pectinirostris) embryos

    Institute of Scientific and Technical Information of China (English)

    CHEN Shixi; HONG Wanshu; ZHANG Qiyong; WU Renxie; WANG Qiong

    2006-01-01

    The rates of oxygen consumption, tolerance of hypoxia and desiccation of the Chinese black sleeper (Bostrichthys sinensis) and mudskipper (Boleophthalmus pectinirostris) embryos were investigated. The pattern of oxygen consumption of the Chinese black sleeper embryos was similar to that of the mudskipper ones. The lowest rates of oxygen consumption[(1.65±0.66)nmol/(ind.·h)] of the Chinese black sleeper embryos 16 h after fertilization and the lowest rates of oxygen consumption [(0.79±0.08)nmol/(ind.·h)] of the mudskipper embryos 6 h after fertilization were recorded, respectively. Then the rates of oxygen consumption of these two species embryos increased gradually until hatching [(8.26±1.70)nmol/(ind.·h)in the Chinese black sleeper, (2.69±0.23)nmol/(ind.·h) in mudskipper]. After exposure to hypoxia water (0.16 mg/dm3), bradycardia of the embryos occurred in both the Chinese black sleeper and the mudskipper. However, the Chinese black sleeper embryos survived approximately 45 min longer than the mudskipper ones. After exposure to desiccation at a relative humidity of 58%, bradycardia of the embryos was observed in both the Chinese black sleeper and the mudskipper, and the Chinese black sleeper embryos lived approximately 9 min longer than the mudskipper ones.

  17. Primary Phases and Natural Weathering of Smelting Slag at an Abandoned Mine Site in Southwest Japan

    Directory of Open Access Journals (Sweden)

    Yuri Sueoka

    2013-12-01

    Full Text Available Artisanal metallurgical slag produced more than 50 years ago at a mine site in southwest Japan is rich in toxic metals and metalloids. Some of the slag remains on a waste dump and could contaminate the surrounding area through the dissolution of heavy metals and metalloids during weathering. To assess this risk, this study has investigated the behavior of the toxic elements in the smelting slag during weathering. Most of the potentially toxic elements are contained in willemite and/or matte drops. Maximum metal and metalloid concentrations in the slag are 28.1 wt % Fe, 22.7 wt % Zn, 1.63 wt % Cu, 3450 mg/kg Sn, 826 mg/kg Pb, 780 mg/kg As, and 116 mg/kg Cd. Zn is mainly contained in willemite, whereas other metals and metalloids are mainly concentrated in matte drops. The willemite and matte drops are converted to Fe-hydroxides during weathering, indicating that potentially toxic metals and metalloids contained in these phases are released by weathering processes. Therefore, weathering of the artisanal metallurgical slag, containing large amounts of willemite and matte drops, may pollute the surrounding environment.

  18. Di-(2-ethylhexyl) adipate and 20 phthalates in composite food samples from the 2013 Canadian Total Diet Study.

    Science.gov (United States)

    Cao, Xu-Liang; Zhao, Wendy; Dabeka, Robert

    2015-01-01

    A sensitive and selective GC-MS method was developed and used for simultaneous analysis of di-(2-ethylhexyl) adipate (DEHA) and 20 selected phthalates in the food samples from the 2013 Canadian Total Diet Study. At least one of the 21 target chemicals was detected in 141 of the 159 different food composite samples analysed. However, only seven of the 21 target chemicals were detected, with di-(2-ethylhexyl) phthalate (DEHP) and DEHA being detected most frequently, in 111 and 91 different food composite samples, respectively, followed by di-n-butyl phthalate (DBP) (n = 44), n-butyl benzyl phthalate (BBzP) (32), di-iso-butyl phthalate (DiBP) (27), di-ethyl phthalate (DEP) (3), and di-cyclohexyl phthalate (DCHP) (1). Levels of DEP (di-ethyl phthalate), DiBP, DBP, BBzP and DCHP were low, in general, with average concentrations of 9.63, 8.26, 23.2, 12.4 and 64.9 ng g(-1), respectively. Levels of DEHA and DEHP varied widely, ranging from 1.4 to 6010 ng g(-1) and from 14.4 to 714 ng g(-1), respectively. High levels of DEHA were found mainly in the composite samples where the individual food items used to prepare the composite were likely packaged in polyvinyl chloride (PVC) wrapping film, while the highest DEHP levels were found in the vegetable and fruit samples.

  19. Endoscopic Retrograde Cholangiopancreatography Using a Dual-Lumen Endogastroscope for Patients with Billroth II Gastrectomy

    Directory of Open Access Journals (Sweden)

    Wei Yao

    2013-01-01

    Full Text Available Objective. To evaluate the safety and efficacy of a dual-lumen forward-viewing endoscope for ERCP in patients with prior Billroth II gastrectomy. Methods. The records of 46 patients treated with ERCP by a dual-lumen forward-viewing endoscope after Billroth II gastrectomy from 2007 to 2012 were reviewed. Results. The success rate of selective cannulation was 82.6% (38/46. Of the 38 cases with successful selective cannulation, endoscopic sphincterotomy was achieved in 23 cases by placing the needle knife through the 2nd lumen, while endoscopic papillary balloon dilatation was conducted in the other 15 cases. Of the 8 failed cases of selective cannulation, 6 had failed afferent loop intubation, and 3 of these 6 patients had Braun’s anastomosis. The safety and efficacy of catheter-assisted endoscopic sphincterotomy were increased by placing the needle knife through the 2nd lumen without altering the conventional endoscopic sphincterotomy procedure. Conclusions. A dual-lumen forward-viewing endoscope can be safely and effectively used to perform ERCP in patients with a Billroth II gastrectomy, except for patients with additional Braun’s anastomosis.

  20. Use of homeopathy in organic dairy farming in Spain.

    Science.gov (United States)

    Orjales, Inmaculada; López-Alonso, Marta; Rodríguez-Bermúdez, Ruth; Rey-Crespo, Francisco; Villar, Ana; Miranda, Marta

    2016-02-01

    Organic farming principles promote the use of unconventional therapies as an alternative to chemical substances (which are limited by organic regulations), with homeopathy being the most extensive. Traditionally, Spain has had little faith in homeopathy but its use in organic farming is growing. Fifty-six Spanish organic dairy farmers were interviewed to obtain what we believe to be the first data on the use of homeopathy in organic dairy cattle in Spain. Only 32% of farms use some sort of alternative therapy (16.1% homeopathy, 10.7% phytotherapy and 5.3% using both therapies) and interestingly, a clear geographical pattern showing a higher use towards the East (similar to that in the human population) was observed. The main motivation to use homeopathy was the need to reduce chemical substances promoted by organic regulations, and the treatment of clinical mastitis being the principle reason. The number of total treatments was lower in farms using homeopathy compared with those applying allopathic therapies (0.13 and 0.54 treatments/cow/year respectively) and although the bulk SCC was significantly higher (p farms (161,826 and 111,218 cel/ml, respectively) it did not have any negative economical penalty for the farmer and milk quality was not affected complying with the required standards; on the contrary homeopathic therapies seems to be an alternative for reducing antibiotic treatments, allowing farmers to meet the organic farming principles.