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Sample records for allowed beta transitions

  1. Isospin impurity and super-allowed {beta} transitions; Impurite d`isospin et transitions {beta} super-permises

    Energy Technology Data Exchange (ETDEWEB)

    Sagawa, H. [Center for Mathematical Science, University of Aizu, Aizu-Wakamatsu, Fukushima 965 (Japan); Van Giai Nguyen [Theoretical Physics Division, Inst. de Physique Nucleaire, Paris-11 Univ., 91 - Orsay (France); Suzuki, T. [Department of Physics, Nihon University, Tokyo 156 (Japan)

    1999-10-01

    We study the effect of isospin impurity on the super-allowed Fermi {beta} decay using microscopic HF and RPA (or TDA) model taking into account CSB and CIB interactions. It is found that the isospin impurity of N = Z nuclei gives enhancement of the sum rule of Fermi transition probabilities. On the other hand, the super-allowed transitions between odd-odd J = 0 nuclei and even-even J = 0 nuclei are quenched because on the cancellation of the isospin impurity effects of mother and daughter nuclei. An implication of the calculated Fermi transition rate on the unitarity of Cabbibo-Kobayashi-Maskawa mixing matrix is also discussed. (authors) 3 refs., 1 fig.

  2. On the theory of beta-radioactivity IV : The polarization of beta-rays emitted by aligned nuclei in allowed transitions

    NARCIS (Netherlands)

    Tolhoek, H.A.; Groot, S.R. de

    The consequences of alignment of nuclei, which show allowed ß-transitions, are investigated. A general formula is derived for the transition probability of an allowed β-transition, in which the direction of emission of electron and neutrino, the polarization of the electron and the orientation of

  3. Allowed unhindered beta connected states in rare earth nuclei

    International Nuclear Information System (INIS)

    Sood, P.C.; Ray, R.S.

    1986-03-01

    The beta-connected states in odd-mass as well as even mass rare earth nuclei, where the transition is of allowed unhindered nature, are listed. The tabulation includes 54 cases of such transitions. Validity of Alaga selection rules is examined and the results are used to assign configurations to the involved single particle and two-particle states. (author)

  4. Super-allowed Fermi beta-decay

    International Nuclear Information System (INIS)

    Wilkinson, D.H.

    2005-01-01

    A final analysis of J π =0 + ->0 + super-allowed Fermi transitions yields vertical bar V ud vertical bar 2 =0.9500±0.0007; vertical bar V ud vertical bar 2 + vertical bar V us vertical bar 2 + vertical bar V ub vertical bar 2 =0.9999±0.0011 with the operational vector coupling constant G V */(-bar c) 3 =(1.15052±0.00021)x10 -5 GeV -2

  5. Analysis of unique beta transitions

    DEFF Research Database (Denmark)

    Eman, B.; Krmpotic, F.; Tadic, D

    1967-01-01

    -non-conserving tensor form factor b > 0. In the former case they contradict Daniel's results [See abstr. 1966A10720] for 0- rarr 0+ transitions, whereas in the latter they are in disagreement with other known analyses of mu-meson capture, allowed and forbidden transitions. The conclusion appears to be independent...... of limited variations of nuclear matrix element ratios. A complete theoretical expression for the shape factor and details of the analysis are presented....

  6. Exotic nuclear beta transitions astrophysical examples

    CERN Document Server

    Takahashi, K

    1981-01-01

    A theoretical study of nuclear beta -transitions under various astrophysical circumstances is reviewed by illustrative examples: 1) continuum-state electron captures in a matter in the nuclear statistical equiplibrium, and ii) bound-state beta -decays in stars in connection with a cosmochronometer and with the s-process branchings. (45 refs).

  7. Analysis of super-allowed Fermi beta-decay

    Energy Technology Data Exchange (ETDEWEB)

    Wilkinson, D H [TRIUMF, Vancouver, BC (Canada); [Sussex Univ., Brighton (United Kingdom)

    1994-11-01

    Analysis of tile J{pi} = 0{sup +} {yields} 0{sup +} super-allowed Fermi transitions within isospin triplets is limited in the precision of its outcome not by the accuracy of the experimental input data nor by the confidence with which the radiative corrections can be applied but by knowledge of the nuclear mismatch: the subversion of the isospin symmetry along the multiplets by the charge-dependence of the forces, both Coulomb and specifically nuclear. Theoretical estimates of the mismatch differ considerably from author to author, their direct application results in clear violation of tile hypothesis of conservation of the vector current and clear inconsistency with unitarity of the Cabibbo-Kobayashi-Maskawa matrix. This paper pursues and elaborates the previous suggestion that, in these unsatisfactory circumstances, the best procedure is to look to the experimental data themselves to determine and eliminate the mismatch by appropriate extrapolation to Z=O. This is done: (i) without any prior correction for mismatch; (ii) after correction for the full theoretical mismatch; (iii) after correction for case-to-case fluctuations in the theoretical mismatch. These three procedures are individually statistically satisfactory and mutually consistent in their extrapolation to Z = 0 despite the variety of the theoretical mismatches on which, in varying degrees, they are based. The resultant unitarity test for the CKM matrix is IV{sub ud}I{sup 2} + IV{sub us}I{sup 2} + IV{sub ub}I{sup 2} = 1.0003 {+-} 0.0014. The associated value for the operational vector coupling constant is: G{sub v}{sup *} / (hc){sup 3} = (1.15155{+-}0.00064) x 10{sup -5} GeV{sup -2}. If unitarity of the CKM matrix is alternatively assumed one may conclude, from a similar analysis, that the mean charge of the fermionic fields between which beta-decay takes place is Q-bar = 0.172{+-}0.060 and that, at the 90% confidence level, b{sub F} < 2.6 x 10{sup -3} were b{sub F} is the relative effective scalar

  8. Analysis of super-allowed Fermi beta-decay

    International Nuclear Information System (INIS)

    Wilkinson, D.H.

    1994-11-01

    Analysis of tile Jπ = 0 + → 0 + super-allowed Fermi transitions within isospin triplets is limited in the precision of its outcome not by the accuracy of the experimental input data nor by the confidence with which the radiative corrections can be applied but by knowledge of the nuclear mismatch: the subversion of the isospin symmetry along the multiplets by the charge-dependence of the forces, both Coulomb and specifically nuclear. Theoretical estimates of the mismatch differ considerably from author to author, their direct application results in clear violation of tile hypothesis of conservation of the vector current and clear inconsistency with unitarity of the Cabibbo-Kobayashi-Maskawa matrix. This paper pursues and elaborates the previous suggestion that, in these unsatisfactory circumstances, the best procedure is to look to the experimental data themselves to determine and eliminate the mismatch by appropriate extrapolation to Z=O. This is done: (i) without any prior correction for mismatch; (ii) after correction for the full theoretical mismatch; (iii) after correction for case-to-case fluctuations in the theoretical mismatch. These three procedures are individually statistically satisfactory and mutually consistent in their extrapolation to Z = 0 despite the variety of the theoretical mismatches on which, in varying degrees, they are based. The resultant unitarity test for the CKM matrix is IV ud I 2 + IV us I 2 + IV ub I 2 = 1.0003 ± 0.0014. The associated value for the operational vector coupling constant is: G v * / (hc) 3 = (1.15155±0.00064) x 10 -5 GeV -2 . If unitarity of the CKM matrix is alternatively assumed one may conclude, from a similar analysis, that the mean charge of the fermionic fields between which beta-decay takes place is Q-bar = 0.172±0.060 and that, at the 90% confidence level, b F -3 were b F is the relative effective scalar coupling constant. Neutron decay is also discussed, with the provisional recommendations: G A * /(hc) 3

  9. Isospin impurity and super-allowed β transitions

    International Nuclear Information System (INIS)

    Sagawa, H.; Van Giai Nguyen; Suzuki, T.

    1999-01-01

    We study the effect of isospin impurity on the super-allowed Fermi β decay using microscopic HF and RPA (or TDA) model taking into account CSB and CIB interactions. It is found that the isospin impurity of N = Z nuclei gives enhancement of the sum rule of Fermi transition probabilities. On the other hand, the super-allowed transitions between odd-odd J = 0 nuclei and even-even J = 0 nuclei are quenched because on the cancellation of the isospin impurity effects of mother and daughter nuclei. An implication of the calculated Fermi transition rate on the unitarity of Cabbibo-Kobayashi-Maskawa mixing matrix is also discussed. (authors)

  10. Allowed and forbidden transition parameters for Fe XV

    International Nuclear Information System (INIS)

    Nahar, Sultana N.

    2009-01-01

    A comprehensive set of fine structure energy levels, oscillator strengths (f), line strengths (S), and radiative decay rates (A) for bound-bound transitions in Fe XV is presented. The allowed electric dipole (E1) transitions were obtained from the relativistic Breit-Pauli R-matrix method which is based on the close coupling approximation. A total of 507 fine structure energy levels with n ≤ 10, l ≤ 9, and 0 ≤ J ≤ 10 are found. They agree within 1% with the available observed energies. These energy levels yield a total of 27,812 E1, same-spin multiplets and intercombination transitions. The A values are in good agreement with those compiled by NIST and other existing values for most transitions. Forbidden transitions are obtained from a set of 20 configurations with orbitals ranging from 1s to 5f using the relativistic code SUPERSTRUCTURE (SS) in the Breit-Pauli approximation. From a set of 123 fine structure levels, a total of 6962 S and A values are presented for forbidden electric quadrupole (E2), electric octupole (E3), magnetic dipole (M1), and magnetic quadrupole (M2) transitions. The energies from SS calculations agree with observed energies to within 1-3%. A values for E2, M1 transitions agree very well with the available values for most transitions while those for M2 transitions show variable agreement. The large set of transition parameters presented should be applicable for both diagnostics and spectral modeling in the X-ray, ultraviolet, and optical regions of astrophysical plasmas.

  11. Study of once and twice forbidden {beta} transitions; Contribution a l'etude de transitions {beta} une fois et deux fois interdites

    Energy Technology Data Exchange (ETDEWEB)

    Hocquenghem, J C [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1967-09-01

    The realisation of an experimental set up for directional angular correlation measurements allowed us to determine {beta} - {gamma} angular correlations. These measurements together with the determination of the {beta} shape-factor have been made for the following transitions: the first forbidden {beta}{sup -} transitions of 386 keV in the {sup 177}Lu disintegration and of 352 keV in the {sup 175}Yb disintegration. The experimental results have been compared with theoretical predictions of the Nilsson's model; the twice forbidden {beta}{sup -} transition of 473 keV in the {sup 94}Nb disintegration. The {beta} transition nuclear matrix elements have been extracted from the experimental results. Comparison have been made with the theoretical values calculated by taking for nuclear wavefunctions those obtained by diagonalization of the residual interaction and assuming that protons and neutrons outside the {sup 90}Zr core are respectively on the 1 g 9/2 and 2 d 5/2 orbits. (author) [French] La realisation d'un ensemble de mesures de correlations angulaires directionnelles nous a permis la mesure de correlations {beta} - {gamma} en fonction de l'energie. En completant celles-ci par la mesure du facteur de forme du spectre {beta}, nous avons pu etudier ainsi: d'une part, les transitions {beta}{sup -} une fois interdites de 386 keV de la desintegration de {sup 177}Lu et de 352 keV de la desintegration de {sup 175}Yb, Les resultats experimentaux ont ete compares aux valeurs calculees dans le modele de Nilsson; d'autre part, la transition {beta}- deux fois interdite de 473 keV de la desintegration de {sup 94}Nb. Les elements de matrice nucleaire de la transition {beta}, extraits des resultats experimentaux, ont ete compares aux valeurs theoriques calculees. Les fonctions d'ondes nucleaires utilisees ont ete obtenues par diagonalisation de l'interaction residuelle en supposant que les protons et les neutrons, en dehors du coeur forme par le {sup 90}Zr, sont respectivement

  12. Beta relaxation of nonpolymeric liquids close to the glass transition

    DEFF Research Database (Denmark)

    Olsen, Niels Boye; Christensen, Tage Emil; Dyre, Jeppe

    2000-01-01

    Dielectric beta relaxation in a pyridine-toluene solution is studied close to the glass transition. Loss peak frequency and maximum loss both exhibit thermal hysteresis. An annealing-state-independent parameter involving loss and loss peak frequency is identified. This parameter has a simple...

  13. Modeling dynamic beta-gamma polymorphic transition in Tin

    Science.gov (United States)

    Chauvin, Camille; Montheillet, Frank; Petit, Jacques; CEA Gramat Collaboration; EMSE Collaboration

    2015-06-01

    Solid-solid phase transitions in metals have been studied by shock waves techniques for many decades. Recent experiments have investigated the transition during isentropic compression experiments and shock-wave compression and have highlighted the strong influence of the loading rate on the transition. Complementary data obtained with velocity and temperature measurements around the polymorphic transition beta-gamma of Tin on gas gun experiments have displayed the importance of the kinetics of the transition. But, even though this phenomenon is known, modeling the kinetic remains complex and based on empirical formulations. A multiphase EOS is available in our 1D Lagrangian code Unidim. We propose to present the influence of various kinetic laws (either empirical or involving nucleation and growth mechanisms) and their parameters (Gibbs free energy, temperature, pressure) on the transformation rate. We compare experimental and calculated velocities and temperature profiles and we underline the effects of the empirical parameters of these models.

  14. Collision strengths for dipole-allowed transitions in S II

    International Nuclear Information System (INIS)

    Ho, Y.K.; Henry, R.J.W.

    1990-01-01

    Calculations of collision strengths for electron-impact excitations of S II from the ground state 3p3 4S0 to excited states 3p4 4P, 3d 4F, 3d 4D, 4s 4P, and 3d 4P were carried out using the R-matrix code described by Berrington et al. (1978) and the NIEM code described by Henry et al. (1981). Results are presented for the thermally averaged collision strengths for the five-state and six-state calculations. Convergence behaviors were examined by comparison with the six-state calculations and the previously obtained two-state calculations. Uncertainties for these transitions were estimated to be within 20 percent, except for the 4S0 - 3p4 4P transition in which a 40 percent uncertainty was estimated. 22 refs

  15. Phase-integral method allowing nearlying transition points

    CERN Document Server

    Fröman, Nanny

    1996-01-01

    The efficiency of the phase-integral method developed by the present au­ thors has been shown both analytically and numerically in many publica­ tions. With the inclusion of supplementary quantities, closely related to new Stokes constants and obtained with the aid of comparison equation technique, important classes of problems in which transition points may approach each other become accessible to accurate analytical treatment. The exposition in this monograph is of a mathematical nature but has important physical applications, some examples of which are found in the adjoined papers. Thus, we would like to emphasize that, although we aim at mathematical rigor, our treatment is made primarily with physical needs in mind. To introduce the reader into the background of this book, we start by de­ scribing the phase-integral approximation of arbitrary order generated from an unspecified base function. This is done in Chapter 1, which is reprinted, after minor changes, from a review article. Chapter 2 is the re...

  16. Search for $\\beta$-transitions with the lowest decay energy for a determination of the neutrino mass

    CERN Multimedia

    From a variety of $\\beta$-transitions only those with decay energies of a few keV and smaller are considered suitable for a determination of the neutrino mass on a sub-eV level. The decay energy of a transition can be very small, if, e.g., in an allowed $\\beta$-decay or electron-capture transition, a nuclear excited state of the daughter nuclide is populated whose energy is very close to the mass difference of the transition nuclides. Investigation of these transitions can also be useful for the assessment of a validity of the current $\\beta$-decay theory in the region of vanishingly small decay energies. The authors of this proposal have found several such $\\beta$-transitions whose decay energies are expected to be extremely small. In order to assess the suitability of these $\\beta$-transitions for the determination of the neutrino mass, measurements of the mass differences of the transition nuclides must be carried out with a sub-keV uncertainty. Presently, only high-precision Penning-trap mass spectrometry...

  17. Hydrogen bonds between the alpha and beta subunits of the F1-ATPase allow communication between the catalytic site and the interface of the beta catch loop and the gamma subunit.

    Science.gov (United States)

    Boltz, Kathryn W; Frasch, Wayne D

    2006-09-19

    F(1)-ATPase mutations in Escherichia coli that changed the strength of hydrogen bonds between the alpha and beta subunits in a location that links the catalytic site to the interface between the beta catch loop and the gamma subunit were examined. Loss of the ability to form the hydrogen bonds involving alphaS337, betaD301, and alphaD335 lowered the k(cat) of ATPase and decreased its susceptibility to Mg(2+)-ADP-AlF(n) inhibition, while mutations that maintain or strengthen these bonds increased the susceptibility to Mg(2+)-ADP-AlF(n) inhibition and lowered the k(cat) of ATPase. These data suggest that hydrogen bonds connecting alphaS337 to betaD301 and betaR323 and connecting alphaD335 to alphaS337 are important to transition state stabilization and catalytic function that may result from the proper alignment of catalytic site residues betaR182 and alphaR376 through the VISIT sequence (alpha344-348). Mutations betaD301E, betaR323K, and alphaR282Q changed the rate-limiting step of the reaction as determined by an isokinetic plot. Hydrophobic mutations of betaR323 decreased the susceptibility to Mg(2+)-ADP-AlF(n)() inhibition and lowered the number of interactions required in the rate-limiting step yet did not affect the k(cat) of ATPase, suggesting that betaR323 is important to transition state formation. The decreased rate of ATP synthase-dependent growth and decreased level of lactate-dependent quenching observed with alphaD335, betaD301, and alphaE283 mutations suggest that these residues may be important to the formation of an alternative set of hydrogen bonds at the interface of the alpha and beta subunits that permits the release of intersubunit bonds upon the binding of ATP, allowing gamma rotation in the escapement mechanism.

  18. Minimally allowed neutrinoless double beta decay rates within an anarchical framework

    International Nuclear Information System (INIS)

    Jenkins, James

    2009-01-01

    Neutrinoless double beta decay (ββ0ν) is the only realistic probe of the Majorana nature of the neutrino. In the standard picture, its rate is proportional to m ee , the e-e element of the Majorana neutrino mass matrix in the flavor basis. I explore minimally allowed m ee values within the framework of mass matrix anarchy where neutrino parameters are defined statistically at low energies. Distributions of mixing angles are well defined by the Haar integration measure, but masses are dependent on arbitrary weighting functions and boundary conditions. I survey the integration measure parameter space and find that for sufficiently convergent weightings, m ee is constrained between (0.01-0.4) eV at 90% confidence. Constraints from neutrino mixing data lower these bounds. Singular integration measures allow for arbitrarily small m ee values with the remaining elements ill-defined, but this condition constrains the flavor structure of the model's ultraviolet completion. ββ0ν bounds below m ee ∼5x10 -3 eV should indicate symmetry in the lepton sector, new light degrees of freedom, or the Dirac nature of the neutrino.

  19. Beta transition rates in hot and dense matter

    International Nuclear Information System (INIS)

    Takahashi, K.; El Eid, M.F.; Hillebrandt, W.

    1977-05-01

    Allowed and first-forbidden transition rates of β +- decays and e +- captures under stellar conditions of high temperatures and high densities are reformulated. The present paper mainly describes the formalism which is essentially based on the gross theory of nuclear β-decays, but also contains the numerical results of the transition rates of nuclei with the mass number 56. The discussion includes a short but critical review of several different approaches to the astrophysical β-transitions of nuclei as well as of the neutron and proton. Further results of the transition rates and the neutrino energy losses will soon be presented elsewhere as simple functions of temperature and density for many nuclei, together with an application to collapsing massive stars. (orig.) [de

  20. Internal bremsstrahlung spectra of the allowed. beta. emitters /sup 32/P, /sup 35/S and /sup 45/Ca

    Energy Technology Data Exchange (ETDEWEB)

    Powar, M S; Singh, M [Punjabi Univ., Patiala (India). Dept. of Physics

    1976-01-01

    A study of Coulomb field effects in internal bremsstrahlung (IB) has been undertaken by measuring the IB spectra for the allowed beta emitters /sup 32/P, /sup 35/S and /sup 45/Ca in the photon energy intervals of 50 to 1600 keV, 25 to 150 keV and 30 to 240 keV respectively. The experimental results show increasing positive departures from the KUB and Coulomb-corrected theories of Lewis and Ford, and Nilsson, with decreasing beta end-point energy. In the case of /sup 35/S the experimental results are 40 % higher than the more exact theory of Struzynski and Pollock for this isotope.

  1. The empirical connection between (p,n) cross sections and beta decay transition strengths

    International Nuclear Information System (INIS)

    Taddeucci, T.N.

    1988-01-01

    A proportionality is assumed to exist between 0/degree/ (p,n) cross sections and the corresponding beta decay transition strengths. The validity of this assumption is tested by comparison of measured (p,n) cross sections and analogous beta decay strengths. Distorted waves impulse approximation calculations also provide useful estimates of the accuracy of the proportionality relationship. 14 refs., 10 figs

  2. Magnet tracking allows assessment of regional gastrointestinal transit times in children.

    Science.gov (United States)

    Hedsund, Caroline; Joensson, Iben Moeller; Gregersen, Tine; Fynne, Lotte; Schlageter, Vincent; Krogh, Klaus

    2013-01-01

    Data on small intestinal transit time in healthy children are lacking, and normal values for gastric emptying and colonic transit time are sparse. Conventional methods, including radiopaque markers, scintigraphy, and PillCam™ involve radiation or require the child to swallow a large pill. The minimally invasive, radiation-free Motility Tracking System-1 (MTS-1) has been introduced for description of gastrointestinal motility in adults. The aim of the study was to evaluate the MTS-1 for assessment of gastrointestinal transit times and motility patterns in healthy children. Twenty-one healthy children (nine girls), median age 10 (range 7-12) years were included. For evaluation with MTS-1, a small magnetic pill was ingested and tracked through the gastrointestinal tract by a matrix of 16 magnetic sensors placed behind a nonmagnetic bed. The children were investigated for 8 hours after swallowing the magnetic pill and again for 4 hours the following morning. After leaving the unit, each child came back after every bowel movement to determine if the pill had been expelled. Nineteen children could swallow the pill. Characteristic contraction patterns were identified for the stomach (three per minute), small intestine (9-11 per minute), and colon (4-5 per minute). Median total gastrointestinal transit time was 37.7 (range 9.5-95.8) hours, median gastric emptying time was 37 (range 2-142) minutes, median small intestinal transit time was 302 (range 164 to >454) minutes, and median colorectal transit time was 38.1 (range 5.6-90.0) hours. MTS-1 allows minimally invasive evaluation of gastrointestinal motility in children. Use of the method is, however, restricted by the nonambulatory setup.

  3. Consistent calculation of the screening and exchange effects in allowed β- transitions

    Science.gov (United States)

    Mougeot, X.; Bisch, C.

    2014-07-01

    The atomic exchange effect has previously been demonstrated to have a great influence at low energy on the Pu241 β- transition. The screening effect has been given as a possible explanation for a remaining discrepancy. Improved calculations have been made to consistently evaluate these two atomic effects, compared here to the recent high-precision measurements of Pu241 and Ni63 β spectra. In this paper a screening correction has been defined to account for the spatial extension of the electron wave functions. Excellent overall agreement of about 1% from 500 eV to the end-point energy has been obtained for both β spectra, which demonstrates that a rather simple β decay model for allowed transitions, including atomic effects within an independent-particle model, is sufficient to describe well the current most precise measurements.

  4. Magnet tracking allows assessment of regional gastrointestinal transit times in children

    Directory of Open Access Journals (Sweden)

    Hedsund C

    2013-11-01

    Full Text Available Caroline Hedsund,1,2 Iben Moeller Joensson,2 Tine Gregersen,1 Lotte Fynne,1 Vincent Schlageter,3 Klaus Krogh1 1Neurogastroenterology Unit, Department of Hepatology and Gastroenterology, 2Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark; 3Motilis Medica SA, Lausanne, Switzerland Background: Data on small intestinal transit time in healthy children are lacking, and normal values for gastric emptying and colonic transit time are sparse. Conventional methods, including radiopaque markers, scintigraphy, and PillCam™ involve radiation or require the child to swallow a large pill. The minimally invasive, radiation-free Motility Tracking System-1 (MTS-1 has been introduced for description of gastrointestinal motility in adults. The aim of the study was to evaluate the MTS-1 for assessment of gastrointestinal transit times and motility patterns in healthy children. Methods: Twenty-one healthy children (nine girls, median age 10 (range 7–12 years were included. For evaluation with MTS-1, a small magnetic pill was ingested and tracked through the gastrointestinal tract by a matrix of 16 magnetic sensors placed behind a nonmagnetic bed. The children were investigated for 8 hours after swallowing the magnetic pill and again for 4 hours the following morning. After leaving the unit, each child came back after every bowel movement to determine if the pill had been expelled. Results: Nineteen children could swallow the pill. Characteristic contraction patterns were identified for the stomach (three per minute, small intestine (9–11 per minute, and colon (4–5 per minute. Median total gastrointestinal transit time was 37.7 (range 9.5–95.8 hours, median gastric emptying time was 37 (range 2–142 minutes, median small intestinal transit time was 302 (range 164 to >454 minutes, and median colorectal transit time was 38.1 (range 5.6–90.0 hours. Conclusion: MTS-1 allows minimally invasive evaluation of gastrointestinal motility in

  5. Nuclear beta decay induced by intense electromagnetic fields: Forbidden transition examples

    International Nuclear Information System (INIS)

    Reiss, H.R.

    1983-01-01

    A formalism developed earlier for the effect on nuclear beta decay of an intense plane-wave electromagnetic field is applied to three examples of forbidden beta transitions. The examples represent cases where the nuclear ''fragment'' contains one, two, and three nucleons; where the nuclear fragment is defined to be that smallest sub-unit of the nucleus containing the nucleon which undergoes beta decay plus any other nucleons directly angular-momentum coupled to it in initial or final states. The single-nucleon-fragment example is 113 Cd, which has a fourth-forbidden transition. The two-nucleon-fragment example is 90 Sr, which is first-forbidden. The three-nucleon-fragment example is 87 Rb, which is third-forbidden. An algebraic closed-form transition probability is found in each case. At low external-field intensity, the transition probability is proportional to z/sup L/, where z is the field intensity parameter and L is the degree of forbiddenness. At intermediate intensities, the transition probability behaves as z/sup L/-(1/2). At higher intensities, the transition probability contains the z/sup L/-(1/2) factor, a declining exponential factor, and an alternating polynomial in z. This high-intensity transition probability possesses a maximum value, which is found for each of the examples. A general rule, z = q 2 (2L-1), where q is the number of particles in the fragment, is found for giving an upper limit on the intensity at which the maximum transition probability occurs. Field-induced beta decay half-lives for all the examples are dramatically reduced from natural half-lives when evaluated at the optimum field intensity. Relative half-life reduction is greater the higher the degree of forbiddenness

  6. Transparent wide band gap crystals follow indirect allowed transition and bipolaron hopping mechanism

    Directory of Open Access Journals (Sweden)

    Feroz A. Mir

    2014-01-01

    Full Text Available Recently, we carried out structural, optical and dielectric studies on micro-crystals of Oxypeucedanin (C16H14O5, isolated from the roots of plant Prangos pabularia (Mir et al. (2014 [3,4]. The obtained trend in frequency exponent (s with frequency (ω indicates that the universal dynamic response is followed by this compound. From optical absorption spectroscopy, the optical band gap (Eg was estimated around 3.76 eV and system is showing indirect allowed transition. Using Eg in certain relation of s, a close value of s (as much close obtained by fitting ac conductivity was obtained. This method was further used for other similar systems and again same trend was obtained. So a general conclusion was made that the high transmitting wide band insulators or semiconductors may follow bipolaron hopping transport mechanism.

  7. Thermally Induced Alpha-Helix to Beta-Sheet Transition in Regenerated Silk Fibers and Films

    Energy Technology Data Exchange (ETDEWEB)

    Drummy,L.; Phillips, D.; Stone, M.; Farmer, B.; Naik, R.

    2005-01-01

    The structure of thin films cast from regenerated solutions of Bombyx mori cocoon silk in hexafluoroisopropyl alcohol (HFIP) was studied by synchrotron X-ray diffraction during heating. A solid-state conformational transition from an alpha-helical structure to the well-known beta-sheet silk II structure occurred at a temperature of approximately 140 degrees C. The transition appeared to be homogeneous, as both phases do not coexist within the resolution of the current study. Modulated differential scanning calorimetry (DSC) of the films showed an endothermic melting peak followed by an exothermic crystallization peak, both occurring near 140 degrees C. Oriented fibers were also produced that displayed this helical molecular conformation. Subsequent heating above the structural transition temperature produced oriented beta-sheet fibers very similar in structure to B. mori cocoon fibers. Heat treatment of silk films at temperatures well below their degradation temperature offers a controllable route to materials with well-defined structures and mechanical behavior.

  8. Meson-Exchange Enhancement of First-Forbidden $\\beta$-Transitions in the Lead Region

    CERN Multimedia

    Delaure, B J P; Severijns, N

    2002-01-01

    Both on-line and off-line low temperature nuclear orientation is used to measure the $\\beta$-asymmetry parameter for the first-forbidden g.s. $\\rightarrow$~g.s. $\\beta$-transitions of $^{205}$Hg, $^{207,209}$Tl, $^{209}$Pb and $^{213}$Bi. From this, the ratio of the rank-zero and the rank-one strengths in these decays can be deduced, with the rank of a $\\beta$-transition being defined as the total angular momentum of the lepton system. Combining this result with the experimental ${ft}$-values yields for the first time a purely experimental determination of the rank-zero contribution in these $\\Delta$ J = 0 first-forbidden transitions. This provides an independent check of the large enhancement (of about 100% over the impulse approximation) of the rank-zero matrix element of $\\gamma_{5} $, caused by meson exchange currents (MEC), which was recently obtained from a comparison of calculated first-forbidden $\\beta$-decay rates with experimentally observed values for nuclei in the lead region (A = 205-212). Measur...

  9. (5/2-→5/2+) 803 keV beta transition in 147Nd

    International Nuclear Information System (INIS)

    Lakshminarayana, S.; Srinivasa Rao, M.; Seshagiri Rao, V.; Sastry, D.L.

    1978-01-01

    The existing experimental results on the 5/2 - →5/2 + 803 keV beta transition in 147 Nd are mutually contradictory to classify it under xi-approximation. To resolve this contradiction, the β-γ directional correlations are performed carefully as a function of energy using a conventional fast-slow coincidence scintillation system. The attenuation factor G 2 in this case turns out to be 0.64 +- 0.05. The results on the longitudinal electron polarization and the shape measurements are combined with the present results and an attempt is made to extract the nuclear matrix elements governing this first forbidden non-unique beta transition following Simm's formalism. Results are discussed based on the final sets of matrix elements. (auth.)

  10. The determination of allowed outage time using the evaluation of transition risk

    International Nuclear Information System (INIS)

    Kang, D. I.; Kim, K. Y.; Jang, S. C.

    2001-03-01

    he objectives of this study are to propose a new evaluation method for transition risk and to determine the AOT using the new method. We review and compare the evaluation methods of transition risk which was previously studied. We also identify important assumptions used in previous studies for the evaluation of transition risk. We select general items required for the development of evaluation method for the transition risk. Based on the items selected, we propose a new evaluation method for transition risk. The new evaluation method for the transition risk is based on following assumptions; 1)For the same time span, the risk occurred from the failure to the completion of component repair during power operation is the same as the total risk including the risk occurred from power operation to specific shutdown/low power operation and the risk from specific shutdown/low power operation to power operation. 2)Shutdown operation and the repair of components are initiated just after the identification of the failure of components. The evaluation of the transition risk is performed to incorporate the characteristics of shutdown operation into Ulchin Units 3 and 4 Level 1 internal PSA for power operation. The application results of the new method to the HPSIS and the LPSIS for Ulchin Units 3 and 4 show that the AOT of HPSIS is properly determined and the AOT of LPSIS can be greatly increased. In this study, the main factors affecting the determination of AOT using the evaluation for transition risk are identified as the time of shutdown operation, the consideration of the change on common cause failure probability, and the risk of shutdown operation. It is expected that the evaluation method for the transition risk proposed in this study will be used for the determination of AOT and for the decision, in the case of the components unavailable, whether power operation is continuously performed or shutdown operation is initiated

  11. Child Home Care Allowance and the Transition to Second- and Third-Order Births in Finland.

    Science.gov (United States)

    Erlandsson, Anni

    2017-01-01

    Using register data from the Finnish Census Panel, this paper studies the relationship between the use of the child home care allowance and second and third births among women aged 20-44 in Finland during the period 1992-2007. Discrete-time event-history analysis is applied to examine (i) whether women taking up the child home care allowance while their previous child was under the age of 3 have a higher risk to proceed to subsequent childbearing, (ii) whether these women proceed to a further birth more quickly, and (iii) whether the risk to proceed to a subsequent birth is related to educational level. The results show that women using the allowance have a higher risk of having a second and a third birth than women not using it. The risk of having a second birth is higher than that of having a third birth. Also, women using the allowance get their subsequent child sooner than women not using the allowance. No large educational differences in the effect of allowance use are found for second or third births.

  12. Child Home Care Allowance: Transition to Second- and Third-Order Births in Finland

    OpenAIRE

    Pajunen, Anni

    2012-01-01

    In this study, I study the relationship between the use of the child home care allowance and second and third births among women aged 19-44 in Finland. I use register data from the Finnish Census Panel (FCP) on 254 465 women who had a second or third child during 1993 to 2007. I apply discrete-time event-history analysis to examine whether women using the child home care allowance while their previous child was under the age of three have a higher risk to proceed to subsequent childbearing – ...

  13. Child Home Care Allowance and the Transition to Second- and Third-Order Births in Finland

    OpenAIRE

    Erlandsson, Anni

    2017-01-01

    Using register data from the Finnish Census Panel, this paper studies the relationship between the use of the child home care allowance and second and third births among women aged 20?44 in Finland during the period 1992?2007. Discrete-time event-history analysis is applied to examine (i) whether women taking up the child home care allowance while their previous child was under the age of 3 have a higher risk to proceed to subsequent childbearing, (ii) whether these women proceed to a further...

  14. Allowance for change in the solvent frequency spectrum in the theory of nonadiabatic transitions

    International Nuclear Information System (INIS)

    Ponomarev, O.A.; Khabibullin, R.M.

    1989-01-01

    An explicit expression is obtained for the correlation function of a vibrational subsystem that takes into account memory of the state of the electron subsystem. The correlation function is represented in terms of the retarded Green's functions of the vibrational subsystem for different electron states. The singular equation for the correlation function are solved by reducing them to a canonical system and to the Riemann problem of the jump of a vector function with subsequent nonlinear factorization. This made it possible to solve exactly the problem for an arbitrary initial correlation function and calculate the effect that a change in the frequency spectrum of the solvent has on the process rate constant in the case of a nonradiative transition

  15. Electron-impact excitation of Fe II: Effective collision strengths for optically allowed fine-structure transitions

    International Nuclear Information System (INIS)

    Ramsbottom, C.A.

    2009-01-01

    In this paper, we present collision strengths and Maxwellian averaged effective collision strengths for the electron-impact excitation of Fe II. We consider specifically the optically allowed lines for transitions from the 3d 6 4s and 3d 7 even parity configuration states to the 3d 6 4p odd parity configuration levels. The parallel suite of Breit-Pauli codes are utilized to compute the collision cross-sections where relativistic effects are included explicitly in both the target and the scattering approximation. A total of 100 LS or 262-jj levels formed from the basis configurations 3d 6 4s, 3d 7 and 3d 6 4p were included in the wavefunction representation of the target, including all doublet, quartet and sextet terms. The Maxwellian averaged effective collision strengths are computed across a wide range of electron temperatures from 100 to 100,000 K, temperatures of importance in astrophysical and plasma applications. A detailed comparison is made with previous works and significant differences were found to occur for some of the transitions considered. We conclude that in order to obtain converged collision strengths and effective collision strengths for these allowed transitions it is necessary to include contributions from partial waves up to L = 50 explicitly in the calculation, and in addition, account for contributions from even higher partial waves through a 'top up' procedure.

  16. Measurement of the beta-gamma directional correlation of the transition 46Sc→46Ti

    International Nuclear Information System (INIS)

    Krexner, G.

    1978-01-01

    Measuring the forward - backward asymmetry of the direction of gamma quanta with respect to the direction of a preceding beta particle emission is one of the methods which have been developed over the past twenty years to investigate parity admixtures in nuclear states. Both theoretical calculations and experiments using this method yield very small values for the considered effect. Moreover the accuracy is limited for statistical reasons. Hence there exists a fundamental interest in proving the experimental arrangement to be free of systematic errors. The subject of this work is an experiment checking a six - detector apparatus which has been used to investigate the beta - gamma directional correlation in the decay 203 Hg→ 203 Tl. For the control measurement the transition 46 Sc→ 46 Ti was chosen. The asymmetry coefficient should yield zero and thus furnish evidence of the absence of systematic errors. The necessary 46 Sc source had to meet very restricting requirements. The feasibility of various methods for producing radioactive samples was reviewed; finally a specially designed high vacuum evaporation plant was constructed. The concept of this device and the preparation of the source are dealt with in detail. A preliminary result of the control experiment is given. However, at present a definite interpretation of the obtained values is not possible. (author)

  17. Order-disorder transition in conflicting dynamics leading to rank-frequency generalized beta distributions

    Science.gov (United States)

    Alvarez-Martinez, R.; Martinez-Mekler, G.; Cocho, G.

    2011-01-01

    The behavior of rank-ordered distributions of phenomena present in a variety of fields such as biology, sociology, linguistics, finance and geophysics has been a matter of intense research. Often power laws have been encountered; however, their validity tends to hold mainly for an intermediate range of rank values. In a recent publication (Martínez-Mekler et al., 2009 [7]), a generalization of the functional form of the beta distribution has been shown to give excellent fits for many systems of very diverse nature, valid for the whole range of rank values, regardless of whether or not a power law behavior has been previously suggested. Here we give some insight on the significance of the two free parameters which appear as exponents in the functional form, by looking into discrete probabilistic branching processes with conflicting dynamics. We analyze a variety of realizations of these so-called expansion-modification models first introduced by Wentian Li (1989) [10]. We focus our attention on an order-disorder transition we encounter as we vary the modification probability p. We characterize this transition by means of the fitting parameters. Our numerical studies show that one of the fitting exponents is related to the presence of long-range correlations exhibited by power spectrum scale invariance, while the other registers the effect of disordering elements leading to a breakdown of these properties. In the absence of long-range correlations, this parameter is sensitive to the occurrence of unlikely events. We also introduce an approximate calculation scheme that relates this dynamics to multinomial multiplicative processes. A better understanding through these models of the meaning of the generalized beta-fitting exponents may contribute to their potential for identifying and characterizing universality classes.

  18. Equation of motion approach for describing allowed transitions in Ne and Al3+ under classical and quantum plasmas

    Science.gov (United States)

    Chaudhuri, Supriya K.; Mukherjee, Prasanta K.; Chaudhuri, Rajat K.; Chattopadhyay, Sudip

    2018-04-01

    The equation of motion coupled cluster methodology within relativistic framework has been applied to analyze the electron correlation effects on the low lying dipole allowed excited states of Ne and Al3+ under classical and quantum plasma environments. The effect of confinement due to classical plasma has been incorporated through screened Coulomb potential, while that of quantum plasma has been treated by exponential cosine screened Coulomb potential. The confined structural properties investigated are the depression of ionization potential, low lying excitation energies (dipole allowed), oscillator strengths, transition probabilities, and frequency dependent polarizabilities under systematic variation of the plasma-atom coupling strength determined through the screening parameter. Specific atomic systems are chosen for their astrophysical importance and availability of experimental data related to laboratory plasma with special reference to Al3+ ion. Here, we consider 1 s22 s22 p6(1S0)→1 s22 s22 p5 n s /n d (1P1) (n =3 ,4 ) dipole allowed transitions of Ne and Al3+. Results for the free (isolated) atomic systems agree well with those available in the literature. Spectroscopic properties under confinement show systematic and interesting pattern with respect to plasma screening parameter.

  19. Ionizing Radiation Promotes Migration and Invasion of Cancer Cells Through Transforming Growth Factor-Beta-Mediated Epithelial-Mesenchymal Transition

    Energy Technology Data Exchange (ETDEWEB)

    Zhou Yongchun [Department of Radiation Oncology, Xijing Hospital Fourth Military Medical University, Xi' an (China); Department of Radiation Medicine, College of Preventive Medicine, Xijing Hospital Fourth Military Medical University, Xi' an (China); Liu Junye; Li Jing; Zhang Jie [Department of Radiation Medicine, College of Preventive Medicine, Xijing Hospital Fourth Military Medical University, Xi' an (China); Xu Yuqiao [Department of Pathology, Xijing Hospital Fourth Military Medical University, Xi' an (China); Zhang Huawei; Qiu Lianbo; Ding Guirong [Department of Radiation Medicine, College of Preventive Medicine, Xijing Hospital Fourth Military Medical University, Xi' an (China); Su Xiaoming [Department of Radiation Oncology, 306th Hospital of PLA, Beijing (China); Mei Shi [Department of Radiation Oncology, Xijing Hospital Fourth Military Medical University, Xi' an (China); Guo Guozhen, E-mail: guozhenguo@hotmail.com [Department of Radiation Medicine, College of Preventive Medicine, Xijing Hospital Fourth Military Medical University, Xi' an (China)

    2011-12-01

    Purpose: To examine whether ionizing radiation enhances the migratory and invasive abilities of cancer cells through transforming growth factor (TGF-{beta})-mediated epithelial-mesenchymal transition (EMT). Methods and Materials: Six cancer cell lines originating from different human organs were irradiated by {sup 60}Co {gamma}-ray at a total dose of 2 Gy, and the changes associated with EMT, including morphology, EMT markers, migration and invasion, were observed by microscope, Western blot, immunofluorescence, scratch assay, and transwell chamber assay, respectively. Then the protein levels of TGF-{beta} in these cancer cells were detected by enzyme-linked immunosorbent assay, and the role of TGF-{beta} signaling pathway in the effect of ionizing radiation on EMT was investigate by using the specific inhibitor SB431542. Results: After irradiation with {gamma}-ray at a total dose of 2 Gy, cancer cells presented the mesenchymal phenotype, and compared with the sham-irradiation group the expression of epithelial markers was decreased and of mesenchymal markers was increased, the migratory and invasive capabilities were strengthened, and the protein levels of TGF-{beta} were enhanced. Furthermore, events associated with EMT induced by IR in A549 could be reversed through inhibition of TGF-{beta} signaling. Conclusions: These results suggest that EMT mediated by TGF-{beta} plays a critical role in IR-induced enhancing of migratory and invasive capabilities in cancer cells.

  20. Research of TGF-beta1 Inducing Lung Adencarcinoma PC9 Cells to Mesenchymal Cells Transition

    Directory of Open Access Journals (Sweden)

    Xiaofeng CHEN

    2010-01-01

    Full Text Available Background and objective It has been proven that epithelial-mesenchymal transition (EMT not only correlated with embryonic development but also could promote tumor invasion and metastasis. Transforming growth factor beta-1 (TGF-β1 has been identified as the main inducer of tumor EMT. The aim of this study was to investigate the effects of TGF-β1 on EMT and PI3K/AKT signaling pathway in lung adencarcinoma PC9 cells. Methods Cultured PC9 cells were treated with different concentrations of TGF-β1 for 48 h. The morphological changes were observed under phase-contrast microscopy; EMT relative marker protein changes were assessed by Western blot and immunoflurescence staining. In addition, the expression of AKT and P-AKT were also measured by Western blot. Results The data showed that TGF-β1 could induce PC9 morphological alteration from epithelial to mesenchymal and upregulate the expression of mesenchymal maker protein Fibronectin. Obviously, the expression of P-AKT was downregulated by TGF-β1 treatment for 48 h. Conclusion TGF-β1 might induce EMT of PC9 cells , accompanied by the changes of PI3K/AKT signaling pathway.

  1. Meson-exchange enhancement of the first forbidden $0^{+} \\leftrightarrow 0^{-} \\beta$-transitions

    CERN Multimedia

    2002-01-01

    In the frame of the standard model of the weak interaction, it has been suggested by Kubodera, Delorme and Rho, that pion exchange should have a large effect on the rank-zero time-like component of the axial current A$_{0}$. The best case for the study of A$ _{0}$ is $0^{-} \\leftrightarrow 0^{+} \\beta$-decay since in this process only rank zero matrix elements of the time-like and space-like components of the axial current contribute to the transition rate. $0^{-} \\leftrightarrow 0^{+}$ decays have been studied in the vicinity of doubly closed-shell nuclei such as $^{16}$O, $^{96}$Zr, and $^{208}$Pb where s$_{1/2} \\leftrightarrow$ p$_{1/2}$ matrix elements were involved. In these cases, the meson-exchange correction to the one-body axial-charge density is significant. ISOLDE offers the possibility to perform sensitive measurements of the $0^{-} \\leftrightarrow 0^{+}$ pseudoscalar decay in nuclei where the p$_{3/2} \\rightarrow$ d$_{3/2}$ matrix elements are involved. We therefore propose a search of the $^{38}...

  2. Nuclear beta decay and the weak interaction

    International Nuclear Information System (INIS)

    Kean, D.C.

    1975-11-01

    Short notes are presented on various aspects of nuclear beta decay and weak interactions including: super-allowed transitions, parity violation, interaction strengths, coupling constants, and the current-current formalism of weak interaction. (R.L.)

  3. In-situ observation of the alpha/beta cristobalite transition using high voltage electron microscopy

    International Nuclear Information System (INIS)

    Meike, A.; Glassley, W.

    1989-10-01

    A high temperature water vapor phase is expected to persist in the vicinity of high level radioactive waste packages for several hundreds of years. The authors have begun an investigation of the structural and chemical effects of water on cristobalite because of its abundance in the near field environment. A high voltage transmission electron microscope (HVEM) investigation of bulk synthesized α-cristobalite to be used in single phase dissolution and precipitation kinetics experiments revealed the presence β-cristobalite, quartz and amorphous silica, in addition to α-cristobalite. Consequently, this apparent metastable persistence of β-cristobalite and amorphous silica during the synthesis of α-cristobalite was investigated using a heating stage and an environmental cell installed in the HVEM that allowed the introduction of either dry CO 2 or a CO 2 + H 2 O vapor. Preliminary electron diffraction evidence suggests that the presence of water vapor affected the α-β transition temperature. Water vapor may also be responsible for the development of an amorphous silica phase at the transition that may persist over an interval of several tens of degrees. The amorphous phase was not documented during the dry heating experiments. 20 refs., 7 figs., 5 tabs

  4. In-situ observation of the alpha/beta cristobalite transition using high voltage electron microscopy

    International Nuclear Information System (INIS)

    Meike, A.; Glassley, W.E.

    1990-01-01

    A high temperature water vapor phase is expected to persist in the vicinity of high level radioactive waste packages for several hundreds of years. The authors have begun an investigation of the structural and chemical effects of water on cristobalite because of its abundance in the near field environment. A high voltage transmission electron microscope (HVEM) investigation of bulk synthesized α-cristobalite to be used in single phase dissolution and precipitation kinetics experiments revealed the presence β-cristobalite, quartz and amorphous silica, in addition to α-cristobalite. Consequently, this apparent metastable persistence of β-cristobalite and amorphous silica during the synthesis of α-cristobalite was investigated using a heating stage and an environmental cell installed in the HVEM that allowed the introduction of either dry CO 2 or a CO 2 + H 2 O vapor. Preliminary electron diffraction evidence suggests that the presence of water vapor affected the α-β transition temperature. Water vapor may also be responsible for the development of an amorphous silica phase at the transition that may persist over an interval of several tens of degrees. The amorphous phase was not documented during the dry heating experiments

  5. Alpha5beta1 integrin-fibronectin interactions specify liquid to solid phase transition of 3D cellular aggregates.

    Directory of Open Access Journals (Sweden)

    Carlos E Caicedo-Carvajal

    2010-07-01

    Full Text Available Tissue organization during embryonic development and wound healing depends on the ability of cells on the one hand to exchange adhesive bonds during active rearrangement and on the other to become fixed in place as tissue homeostasis is reached. Cells achieve these contradictory tasks by regulating either cell-cell adhesive bonds, mediated by cadherins, or cell-extracellular matrix (ECM connections, regulated by integrins. Integrin alpha5beta1 and soluble fibronectin (sFN are key players in cell-ECM force generation and in ECM polymerization. Here, we explore the interplay between integrin alpha5beta1 and sFN and its influence on tissue mechanical properties and cell sorting behavior.We generated a series of cell lines varying in alpha5beta1 receptor density. We then systematically explored the effects of different sFN concentrations on aggregate biomechanical properties using tissue surface tensiometry. We found previously unreported complex behaviors including the observation that interactions between fibronectin and integrin alpha5beta1 generates biphasic tissue cohesion profiles. Specifically, we show that at constant sFn concentration, aggregate cohesion increases linearly as alpha5beta1 receptor density is increased from low to moderate levels, producing a transition from viscoelastic-liquid to pseudo viscoelastic-solid behavior. However, further increase in receptor density causes an abrupt drop in tissue cohesion and a transition back to viscoelastic-liquid properties. We propose that this may be due to depletion of sFn below a critical value in the aggregate microenvironment at high alpha5beta1 levels. We also show that differential expression of alpha5beta1 integrin can promote phase-separation between cells.The interplay between alpha5-integrin and sFn contributes significantly to tissue cohesion and, depending on their level of expression, can mediate a shift from liquid to elastic behavior. This interplay represents a tunable level

  6. Beta decay of the fission product 125Sb and a new complete evaluation of absolute gamma ray transition intensities

    Science.gov (United States)

    Rajput, M. U.; Ali, N.; Hussain, S.; Mujahid, S. A.; MacMahon, D.

    2012-04-01

    The radionuclide 125Sb is a long-lived fission product, which decays to 125Te by negative beta emission with a half-life of 1008 day. The beta decay is followed by the emission of several gamma radiations, ranging from low to medium energy, that can suitably be used for high-resolution detector calibrations, decay heat calculations and in many other applications. In this work, the beta decay of 125Sb has been studied in detail. The complete published experimental data of relative gamma ray intensities in the beta decay of the radionuclide 125Sb has been compiled. The consistency analysis was performed and discrepancies found at several gamma ray energies. Evaluation of the discrepant data was carried out using Normalized Residual and RAJEVAL methods. The decay scheme balance was carried out using beta branching ratios, internal conversion coefficients, populating and depopulating gamma transitions to 125Te levels. The work has resulted in the consistent conversion factor equal to 29.59(13) %, and determined a new evaluated set of the absolute gamma ray emission probabilities. The work has also shown 22.99% of the delayed intensity fraction as outgoing from the 58 d isomeric 144 keV energy level and 77.01% of the prompt intensity fraction reaching to the ground state from the other excited states. The results are discussed and compared with previous evaluations. The present work includes additional experimental data sets which were not included in the previous evaluations. A new set of recommended relative and absolute gamma ray emission probabilities is presented.

  7. Beta decay of the fission product 125Sb and a new complete evaluation of absolute gamma ray transition intensities

    International Nuclear Information System (INIS)

    Rajput, M.U.; Ali, N.; Hussain, S.; Mujahid, S.A.; MacMahon, D.

    2012-01-01

    The radionuclide 125 Sb is a long-lived fission product, which decays to 125 Te by negative beta emission with a half-life of 1008 day. The beta decay is followed by the emission of several gamma radiations, ranging from low to medium energy, that can suitably be used for high-resolution detector calibrations, decay heat calculations and in many other applications. In this work, the beta decay of 125 Sb has been studied in detail. The complete published experimental data of relative gamma ray intensities in the beta decay of the radionuclide 125 Sb has been compiled. The consistency analysis was performed and discrepancies found at several gamma ray energies. Evaluation of the discrepant data was carried out using Normalized Residual and RAJEVAL methods. The decay scheme balance was carried out using beta branching ratios, internal conversion coefficients, populating and depopulating gamma transitions to 125 Te levels. The work has resulted in the consistent conversion factor equal to 29.59(13) %, and determined a new evaluated set of the absolute gamma ray emission probabilities. The work has also shown 22.99% of the delayed intensity fraction as outgoing from the 58 d isomeric 144 keV energy level and 77.01% of the prompt intensity fraction reaching to the ground state from the other excited states. The results are discussed and compared with previous evaluations. The present work includes additional experimental data sets which were not included in the previous evaluations. A new set of recommended relative and absolute gamma ray emission probabilities is presented.

  8. Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor signals in cells expressing both receptor types.

    Science.gov (United States)

    Vassbotn, F S; Ostman, A; Siegbahn, A; Holmsen, H; Heldin, C H

    1992-08-05

    The aminoglycoside neomycin has recently been found to affect certain platelet-derived growth factor (PDGF) responses in C3H/10T1/2 C18 fibroblasts. Using porcine aortic endothelial cells transfected with PDGF alpha- or beta-receptors, we explored the possibility that neomycin interferes with the interaction between the different PDGF isoforms and their receptors. We found that neomycin (5 mM) inhibited the binding of 125I-PDGF-BB to the alpha-receptor with only partial effect on the binding of 125I-PDGF-AA; in contrast, the binding of 125I-PDGF-BB to the beta-receptor was not affected by the aminoglycoside. Scatchard analyses showed that neomycin (5 mM) decreased the number of binding sites for PDGF-BB on alpha-receptor-expressing cells by 87%. Together with cross-competition studies with 125I-labeled PDGF homodimers, the effect of neomycin indicates that PDGF-AA and PDGF-BB bind to both common and unique structures on the PDGF alpha-receptor. Neomycin specifically inhibited the autophosphorylation of the alpha-receptor by PDGF-BB, with less effect on the phosphorylation induced by PDGF-AA and no effect on the phosphorylation of the beta-receptor by PDGF-BB. Thus, neomycin is a PDGF isoform- and receptor-specific antagonist that provides a possibility to compare the signal transduction pathways of alpha- and beta-receptors in cells expressing both receptor types. This approach was used to show that activation of PDGF beta-receptors by PDGF-BB mediated a chemotactic response in human fibroblasts, whereas activation of alpha-receptors by the same ligand inhibited chemotaxis.

  9. Electric-dipole allowed and intercombination transitions among the 3d5, 3d44s and 3d44p levels of Fe IV

    International Nuclear Information System (INIS)

    Deb, Narayan C.; Hibbert, Alan

    2010-01-01

    Oscillator strengths and transition rates for the electric-dipole (E1) allowed and intercombination transitions among 3d 5 , 3d 4 4s and 3d 4 4p levels of Fe IV are calculated using the CIV3 code of Hibbert and coworkers. Using the Hartree-Fock functions up to 3d orbitals we have also optimized 4s, 4p, 4d, 4f, 5s, 5p and 5d orbitals of which 4s and 4p are taken to be spectroscopic and the remaining orbitals represent corrections to the spectroscopic orbitals or the correlation effects. The J-dependent levels of 108 LS states are included in the calculation and the relativistic effects are accounted for via the Breit-Pauli operator. Configurations are chosen in two steps: (a) two promotions were allowed from the 3p, 3d, 4s and 4p subshells, using all the orbitals; and (b) selective promotions from the 3s subshell are included, but only to the 3s and 4s orbitals. The ab initio fine-structure levels are then fine tuned to reproduce observed energy levels as closely as possible, and the resulting wavefunctions are used to calculate oscillator strengths and transition rates for all possible E1 transitions. For many of these transitions, the present results show good agreement between the length and velocity forms while for some transitions, some large disagreements are found with other available results. The complete list of weighted oscillator strengths, transition rates, and line strengths for transitions among the fine structure levels of the three lowest configurations are presented in ascending order of wavelength.

  10. The Kπ = 0+ bands of 178Hf and the allowed unhindered beta transformations of 9.3 min 178Ta and 22 d 178W

    DEFF Research Database (Denmark)

    Nielsen, H.L.; Wilsky, K.; Zylicz, J.

    1967-01-01

    established at 1199(0+), 1276(2+), 1434(0+), 1444(0+), 1496(2+), 1514(2+, 1+ or 1−) and 1561(2+). The 1199 keV state is interpreted as a beta vibration, the 1434 and 1444 keV 0+ states contain probably large amplitudes of the View the MathML source [514] neutron pair of the View the MathML source[514] proton...

  11. Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition.

    Directory of Open Access Journals (Sweden)

    Serena Battaglia

    Full Text Available BACKGROUND: Chronic hepatitis C virus (HCV infection and associated liver cirrhosis represent a major risk factor for hepatocellular carcinoma (HCC development. TGF-beta is an important driver of liver fibrogenesis and cancer; however, its actual impact in human cancer progression is still poorly known. The aim of this study was to investigate the role of HCC-derived HCV core natural variants on cancer progression through their impact on TGF-beta signaling. PRINCIPAL FINDINGS: We provide evidence that HCC-derived core protein expression in primary human or mouse hepatocyte alleviates TGF-beta responses in terms or growth inhibition or apoptosis. Instead, in these hepatocytes TGF-beta was still able to induce an epithelial to mesenchymal transition (EMT, a process that contributes to the promotion of cell invasion and metastasis. Moreover, we demonstrate that different thresholds of Smad3 activation dictate the TGF-beta responses in hepatic cells and that HCV core protein, by decreasing Smad3 activation, may switch TGF-beta growth inhibitory effects to tumor promoting responses. CONCLUSION/SIGNIFICANCE: Our data illustrate the capacity of hepatocytes to develop EMT and plasticity under TGF-beta, emphasize the role of HCV core protein in the dynamic of these effects and provide evidence for a paradigm whereby a viral protein implicated in oncogenesis is capable to shift TGF-beta responses from cytostatic effects to EMT development.

  12. Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA.

    Science.gov (United States)

    Zhao, Bryan M; Hoffmann, F Michael

    2006-09-01

    Overexpression of the inhibitory Smad, Smad7, is used frequently to implicate the Smad pathway in cellular responses to transforming growth factor beta (TGF-beta) signaling; however, Smad7 regulates several other proteins, including Cdc42, p38MAPK, and beta-catenin. We report an alternative approach for more specifically disrupting Smad-dependent signaling using a peptide aptamer, Trx-SARA, which comprises a rigid scaffold, the Escherichia coli thioredoxin A protein (Trx), displaying a constrained 56-amino acid Smad-binding motif from the Smad anchor for receptor activation (SARA) protein. Trx-SARA bound specifically to Smad2 and Smad3 and inhibited both TGF-beta-induced reporter gene expression and epithelial-to-mesenchymal transition in NMuMG murine mammary epithelial cells. In contrast to Smad7, Trx-SARA had no effect on the Smad2 or 3 phosphorylation levels induced by TGF-beta1. Trx-SARA was primarily localized to the nucleus and perturbed the normal cytoplasmic localization of Smad2 and 3 to a nuclear localization in the absence of TGF-beta1, consistent with reduced Smad nuclear export. The key mode of action of Trx-SARA was to reduce the level of Smad2 and Smad3 in complex with Smad4 after TGF-beta1 stimulation, a mechanism of action consistent with the preferential binding of SARA to monomeric Smad protein and Trx-SARA-mediated disruption of active Smad complexes.

  13. Contribution to the study of once-forbidden {beta} transitions. Case of {sup 42}K and {sup 86}Rb; Contribution a l'etude des transitions {beta} une fois interdites. Cas de K{sup 42} et Rb{sup 86}

    Energy Technology Data Exchange (ETDEWEB)

    Andre, St [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1965-10-01

    An apparatus has been developed for studying the exact shape of the spectra of {beta} transitions which lead to an excited state of the final nucleus, using a Siegbahn-Slattis {beta} spectrometer. In particular the {beta} spectrum of the 2- {yields} 2+ transition of {sup 42}K has been measured; a considerable deviation has been found with respect to the statistical shape. The six elements of the nuclear matrices for this transition have been determined using this measurement and other results. It is shown that it cannot be explained by a pure f7/2 {yields} d3/2 transition. Furthermore the value obtained for the ratio of the matrix elements {integral}{alpha} and {integral}r is in excellent agreement with that predicted from the theory for the maintained vectorial current. (author) [French] On a realise et mis au point un appareillage permettant l'etude des formes precises des spectres {beta} des transitions aboutissant a un etat excite du noyau final sur un spectrometre {beta} Siegbahn-Slatis. On a mesure notamment le spectre {beta} de la transition 2- {yields} 2+ du K{sup 42}, mettant en evidence une deviation importante par rapport a la forme statistique. A partir de cette mesure et d'autres resultats, on a determine les six elements de matrice nucleaires de cette transition. On montre qu'elle ne peut pas etre expliquee par une transition f7/2 {yields} d3/2 pure. D'autre part, la valeur obtenue pour le rapport des elements de matrice {integral}{alpha} et {integral}r est en excellent accord avec celle qui est prevue a partir de la theorie du courant vectoriel conserve. (auteur)

  14. Fluid sensitive nanoscale switching with quantum levitation controlled by $\\alpha$-Sn/$\\beta$-Sn phase transition

    OpenAIRE

    Boström, Mathias; Dou, Maofeng; Malyi, Oleksandr I.; Parashar, Prachi; Parsons, Drew F.; Brevik, Iver; Persson, Clas

    2018-01-01

    We analyze the Lifshitz pressure between silica and tin separated by a liquid mixture of bromobenzene and chlorobenzene. We show that the phase transition from semimetallic α−Sn to metallic β−Sn can switch Lifshitz forces from repulsive to attractive. This effect is caused by the difference in dielectric functions of α−Sn and β−Sn, giving both attractive and repulsive contributions to the total Lifshitz pressure in different frequency regions controlled by the composition of the intervening l...

  15. Refinement of the gross theory of nuclear {beta}-decay, and hindrance of the first-forbidden transition of rank 1

    Energy Technology Data Exchange (ETDEWEB)

    Nakata, Hidehiko [Waseda Univ., Tokyo (Japan). Dept. of Physics; Tachibana, Takahiro; Yamada, Masami

    1997-03-01

    Recently the gross theory of nuclear {beta}-decay was refined for odd-odd nuclei. In this refinement, the effect of the selection rule of {beta}-transitions from the ground states of odd-odd nuclei to those of even-even nuclei was taken into account based on a statistical consideration. The transitions to the first 2{sup +} excited states in even-even nuclei were also taken into account according to the selection rule approximately. In that study, it was found that the transitions between 1{sup -} ground states of the odd-odd nuclei and 0{sup +} ground states of even-even nuclei, belonging to the first-forbidden transitions of rank 1, are strongly hindered. A reduction factor was introduced for the transitions to the ground states of even-even nuclei to take into account this hindrance. It was also found that the strength functions of the Gamow-Teller transitions obtained from the conventional gross theory are underestimated by a factor of about 3. In order to improve this underestimation, the Lorentz-type function was adopted for the one-particle strength function in the model instead of the hyperbolic-secant-type function. In the present study we have newly analyzed the experimental ft-values of odd-A nuclei, and found that the first-forbidden transitions of rank 1 are also considerably hindered between the ground states. Following the above refinement we have calculated the {beta}-ray spectra of some odd-odd short-lived fission products with the use of the refined gross theory. These results are compared not only with the experiments by Rudstam et al. but also with the conventional gross theory. (author)

  16. Structural transitions in superionic conductors

    Energy Technology Data Exchange (ETDEWEB)

    Parrinello, M.; Rahman, A.; Vashishta, P.

    1983-04-04

    The ..cap alpha..arrow-right-left..beta.. phase transition in AgI is studied with use of the new molecular-dynamics technique which allows for a dynamical variation of the shape and size of the cell. In the present model, upon heating of ..beta..-AgI, the iodine ions undergo a hcp..-->..bcc transformation and silver ions become mobile, whereas the reverse transformation is observed on cooling of ..cap alpha..-AgI. The calculated ..cap alpha..arrow-right-left..beta.. transition temperature and structural and dynamical properties are in good agreement with experiments.

  17. GSTA3 Attenuates Renal Interstitial Fibrosis by Inhibiting TGF-Beta-Induced Tubular Epithelial-Mesenchymal Transition and Fibronectin Expression.

    Directory of Open Access Journals (Sweden)

    Yun Xiao

    Full Text Available Tubular epithelial-mesenchymal transition (EMT has been widely accepted as the underlying mechanisms of renal interstitial fibrosis (RIF. The production of reactive oxygen species (ROS plays a vital role in tubular EMT process. The purpose of this study was to investigate the involved molecular mechanisms in TGF-beta-induced EMT and identify the potential role of glutathione S-transferase alpha 3 (GSTA3 in this process. The iTRAQ screening was performed to identify protein alterations of the rats underwent unilateral-ureteral obstruction (UUO. Protein expression of GSTA3 in patients with obstructive nephropathy and UUO rats was detected by immunohistochemistry. Protein and mRNA expression of GSTA3 in UUO rats and NRK-52E cells were determined by Western blot and RT-PCR. siRNA and overexpression plasmid were transfected specifically to assess the role of GSTA3 in RIF. The generation of ROS was measured by dichlorofluorescein fluorescence analysis. GSTA3 protein and mRNA expression was significantly reduced in UUO rats. Immunohistochemical analysis revealed that GSTA3 expression was reduced in renal cortex in UUO rats and patients with obstructive nephropathy. Treating with TGF-β1 down-regulated GSTA3 expression in NRK-52E cells, which have been found to be correlated with the decreased expression in E-cadherin and megalin and increased expression in α-smooth muscle actin. Furthermore, knocking down GSTA3 in NRK-52 cells led to increased production of ROS and tubular EMT, whereas overexpressing GSTA3 ameliorated ROS production and prevented the occurrence of tubular EMT. GSTA3 plays a protective role against tubular EMT in renal fibrosis, suggesting GSTA3 is a potential therapeutic target for RIF.

  18. CHILD ALLOWANCE

    CERN Multimedia

    Human Resources Division

    2001-01-01

    HR Division wishes to clarify to members of the personnel that the allowance for a dependent child continues to be paid during all training courses ('stages'), apprenticeships, 'contrats de qualification', sandwich courses or other courses of similar nature. Any payment received for these training courses, including apprenticeships, is however deducted from the amount reimbursable as school fees. HR Division would also like to draw the attention of members of the personnel to the fact that any contract of employment will lead to the suppression of the child allowance and of the right to reimbursement of school fees.

  19. Experimental proof of quantum non-separability based on the transition of the atom in beta-decay

    International Nuclear Information System (INIS)

    Vatai, E.

    1988-01-01

    The basic non-local character of the quantum processes is a continuously discussed and doubted problem of quantum theory. Recent experimental proofs of the Bell inequalities are questioned in the literature, using local theories of hidden variables. Present paper shows a simple and direct proof of non-locality of quantum processes, analyzing the case of the beta decay. The hypothetical energy transfer between shell electrons and beta electron-neutrino system is proved to be superluminal but necessary for the energy balance of the process. This argumentation proves the nonseparability and nonlocality of quantum processes. (D.G.) 8 refs

  20. Negotiating the COAPRT Learning Outcomes Transition Using Quality Management Tools: A Case Study of the COAPRT Beta Test Site

    Science.gov (United States)

    Ellis, Gary D.

    2014-01-01

    This paper is a case study. It tells the story of the process that the Council on Accreditation for Parks, Recreation, Tourism and Related Professions beta test site created its learning outcomes assessment program. A planning process was used that has evolved from quality management philosophy and practice: DMADV. Use of DMADV required precise…

  1. Sources of beta diversity in estuarine benthic macro-invertebrate communities in the Baltic Sea - North Sea transition

    DEFF Research Database (Denmark)

    Josefson, Alf B.; Göke, Cordula

    Identification of sources of beta diversity, the change of diversity, is important to understand regulation of overall diversity. Additive partitioning of diversity (species richness and expH) compared to random, was performed on a quantitative benthic macro-invertebrate collection of > 400 speci...

  2. Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors.

    Directory of Open Access Journals (Sweden)

    Xian Zhang

    Full Text Available Epithelial-mesenchymal transition (EMT is the first step required for breast cancer to initiate metastasis. However, the potential of drugs to block and reverse the EMT process are not well explored. In the present study, we investigated the inhibitory effect of beta-elemene (ELE, an active component of a natural plant-derived anti-neoplastic agent in an established EMT model mediated by transforming growth factor-beta1 (TGF-β1. We found that ELE (40 µg/ml blocked the TGF-β1-induced phenotypic transition in the human breast cancer cell line MCF-7. ELE was able to inhibit TGF-β1-mediated upregulation of mRNA and protein expression of nuclear transcription factors (SNAI1, SNAI2, TWIST and SIP1, potentially through decreasing the expression and phosphorylation of Smad3, a central protein mediating the TGF-β1 signalling pathway. These findings suggest a potential therapeutic benefit of ELE in treating basal-like breast cancer.

  3. Transcriptional Alterations of Virulence-Associated Genes in Extended Spectrum Beta-Lactamase (ESBL-Producing Uropathogenic Escherichia coli during Morphologic Transitions Induced by Ineffective Antibiotics

    Directory of Open Access Journals (Sweden)

    Isak Demirel

    2017-06-01

    Full Text Available It is known that an ineffective antibiotic treatment can induce morphological shifts in uropathogenic Escherichia coli (UPEC but the virulence properties during these shifts remain to be studied. The present study examines changes in global gene expression patterns and in virulence factor-associated genes in an extended spectrum beta-lactamase (ESBL-producing UPEC (ESBL019 during the morphologic transitions induced by an ineffective antibiotic and in the presence of human primary bladder epithelial cells. Microarray results showed that the different morphological states of ESBL019 had significant transcriptional alterations of a large number of genes (Transition; 7%, Filamentation; 32%, and Reverted 19% of the entities on the array. All three morphological states of ESBL019 were associated with a decreased energy metabolism, altered iron acquisition systems and altered adhesion expression. In addition, genes associated with LPS synthesis and bacterial motility was also altered in all the morphological states. Furthermore, the transition state induced a significantly higher release of TNF-α from bladder epithelial cells compared to all other morphologies, while the reverted state was unable to induce TNF-α release. Our findings show that the morphological shifts induced by ineffective antibiotics are associated with significant transcriptional virulence alterations in ESBL-producing UPEC, which may affect survival and persistence in the urinary tract.

  4. In-trap decay spectroscopy for {beta}{beta} decays

    Energy Technology Data Exchange (ETDEWEB)

    Brunner, Thomas

    2011-01-18

    The presented work describes the implementation of a new technique to measure electron-capture (EC) branching ratios (BRs) of intermediate nuclei in {beta}{beta} decays. This technique has been developed at TRIUMF in Vancouver, Canada. It facilitates one of TRIUMF's Ion Traps for Atomic and Nuclear science (TITAN), the Electron Beam Ion Trap (EBIT) that is used as a spectroscopy Penning trap. Radioactive ions, produced at the radioactive isotope facility ISAC, are injected and stored in the spectroscopy Penning trap while their decays are observed. A key feature of this technique is the use of a strong magnetic field, required for trapping. It radially confines electrons from {beta} decays along the trap axis while X-rays, following an EC, are emitted isotropically. This provides spatial separation of X-ray and {beta} detection with almost no {beta}-induced background at the X-ray detector, allowing weak EC branches to be measured. Furthermore, the combination of several traps allows one to isobarically clean the sample prior to the in-trap decay spectroscopy measurement. This technique has been developed to measure ECBRs of transition nuclei in {beta}{beta} decays. Detailed knowledge of these electron capture branches is crucial for a better understanding of the underlying nuclear physics in {beta}{beta} decays. These branches are typically of the order of 10{sup -5} and therefore difficult to measure. Conventional measurements suffer from isobaric contamination and a dominating {beta} background at theX-ray detector. Additionally, X-rays are attenuated by the material where the radioactive sample is implanted. To overcome these limitations, the technique of in-trap decay spectroscopy has been developed. In this work, the EBIT was connected to the TITAN beam line and has been commissioned. Using the developed beam diagnostics, ions were injected into the Penning trap and systematic studies on injection and storage optimization were performed. Furthermore, Ge

  5. BETA digital beta radiometer

    International Nuclear Information System (INIS)

    Borovikov, N.V.; Kosinov, G.A.; Fedorov, Yu.N.

    1989-01-01

    Portable transportable digital beta radiometer providing for measuring beta-decay radionuclide specific activity in the range from 5x10 -9 up to 10 -6 Cu/kg (Cu/l) with error of ±25% is designed and introduced into commercial production for determination of volume and specific water and food radioactivity. The device specifications are given. Experience in the BETA radiometer application under conditions of the Chernobyl' NPP 30-km zone has shown that it is convenient for measuring specific activity of the order of 10 -8 Cu/kg, and application of a set of different beta detectors gives an opportunity to use it for surface contamination measurement in wide range of the measured value

  6. TRANSIT

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. TRANSIT. SYSTEM: DETERMINE 2D-POSITION GLOBALLY BUT INTERMITTENT (POST-FACTO). IMPROVED ACCURACY. PRINCIPLE: POLAR SATELLITES WITH INNOVATIONS OF: GRAVITY-GRADIENT ATTITUDE CONTROL; DRAG COMPENSATION. WORKS ...

  7. Cross sections and oscillator strengths for electron-impact excitation of electronic states in polyatomic molecules. Application examples of the BEf- scaling model in optically-allowed transitions

    International Nuclear Information System (INIS)

    Kato, H.; Kawahara, H.; Hoshino, M.

    2009-12-01

    Integral cross sections for optically allowed electronic-state excitations by electron impact, are reviewed for polyatomic molecules by applying the Binary-Encounter-Bethe (BEB) scaling model. Following the context of the present review, the scaling model originally proposed by Yong-Ki Kim to determine electron-impact cross sections for ionization of atoms and molecules is also summarized briefly for its wide range of applications [Electron-Impact Cross Section Database, NIST, Y.-K. Kim]. The present report not only focuses on the need for the cross-section data, but also elucidates the verification of the scaling model in the general application for atoms and molecules. Since this report is for a data base, it is summarized for data base users by citing (copying) the descriptions in the original papers and the references within those papers in the style of a textbook. (author)

  8. Long Non-Coding RNA MALAT1 Mediates Transforming Growth Factor Beta1-Induced Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells.

    Directory of Open Access Journals (Sweden)

    Shuai Yang

    Full Text Available To study the role of long non-coding RNA (lncRNA MALAT1 in transforming growth factor beta 1 (TGF-β1-induced epithelial-mesenchymal transition (EMT of retinal pigment epithelial (RPE cells.ARPE-19 cells were cultured and exposed to TGF-β1. The EMT of APRE-19 cells is confirmed by morphological change, as well as the increased expression of alpha-smooth muscle actin (αSMA and fibronectin, and the down-regulation of E-cadherin and Zona occludin-1(ZO-1 at both mRNA and protein levels. The expression of lncRNA MALAT1 in RPE cells were detected by quantitative real-time PCR. Knockdown of MALAT1 was achieved by transfecting a small interfering RNA (SiRNA. The effect of inhibition of MALAT1 on EMT, migration, proliferation, and TGFβ signalings were observed. MALAT1 expression was also detected in primary RPE cells incubated with proliferative vitreoretinopathy (PVR vitreous samples.The expression of MALAT1 is significantly increased in RPE cells incubated with TGFβ1. MALAT1 silencing attenuates TGFβ1-induced EMT, migration, and proliferation of RPE cells, at least partially through activating Smad2/3 signaling. MALAT1 is also significantly increased in primary RPE cells incubated with PVR vitreous samples.LncRNA MALAT1 is involved in TGFβ1-induced EMT of human RPE cells and provides new understandings for the pathogenesis of PVR.

  9. Inhibition of glycogen synthase kinase 3beta ameliorates triptolide-induced acute cardiac injury by desensitizing mitochondrial permeability transition

    International Nuclear Information System (INIS)

    Wang, Wenwen; Yang, Yanqin; Xiong, Zhewen; Kong, Jiamin; Fu, Xinlu; Shen, Feihai; Huang, Zhiying

    2016-01-01

    Triptolide (TP), a diterpene triepoxide, is a major active component of Tripterygium wilfordii extracts, which are prepared as tablets and has been used clinically for the treatment of inflammation and autoimmune disorders. However, TP's therapeutic potential is limited by severe adverse effects. In a previous study, we reported that TP induced mitochondria dependent apoptosis in cardiomyocytes. Glycogen synthase kinase-3β (GSK-3β) is a multifunctional serine/threonine kinase that plays important roles in the necrosis and apoptosis of cardiomyocytes. Our study aimed to investigate the role of GSK-3β in TP-induced cardiotoxicity. Inhibition of GSK-3β activity by SB 216763, a potent and selective GSK-3 inhibitor, prominently ameliorated the detrimental effects in C57BL/6J mice with TP administration, which was associated with a correction of GSK-3β overactivity. Consistently, in TP-treated H9c2 cells, SB 216763 treatment counteracted GSK-3β overactivity, improved cell viability, and prevented apoptosis by modulating the expression of Bcl-2 family proteins. Mechanistically, GSK-3β interacted with and phosphorylated cyclophilin F (Cyp-F), a key regulator of mitochondrial permeability transition pore (mPTP). GSK-3β inhibition prevented the phosphorylation and activation of Cyp-F, and desensitized mPTP. Our findings suggest that pharmacological targeting of GSK-3β could represent a promising therapeutic strategy for protecting against cardiotoxicity induced by TP. - Highlights: • GSK-3β inhibition ameliorates TP-induced cardiotoxicity in vitro and in vivo. • GSK-3β controls Cyp-F activation, and regulates mPTP and apoptosis in H9c2 cells. • The protective effect is attributed to GSK-3β activity rather than to protein level. • GSK-3β may be a promising target against TP-induced cardiotoxicity.

  10. Inhibition of glycogen synthase kinase 3beta ameliorates triptolide-induced acute cardiac injury by desensitizing mitochondrial permeability transition

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Wenwen; Yang, Yanqin; Xiong, Zhewen; Kong, Jiamin [School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006 (China); Fu, Xinlu [Laboratory Animals Center, Sun Yat-sen University, Guangzhou 510006 (China); Shen, Feihai, E-mail: shenfh3@mail.sysu.edu.cn [School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006 (China); Huang, Zhiying, E-mail: hzhiying@mail.sysu.edu.cn [School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006 (China)

    2016-12-15

    Triptolide (TP), a diterpene triepoxide, is a major active component of Tripterygium wilfordii extracts, which are prepared as tablets and has been used clinically for the treatment of inflammation and autoimmune disorders. However, TP's therapeutic potential is limited by severe adverse effects. In a previous study, we reported that TP induced mitochondria dependent apoptosis in cardiomyocytes. Glycogen synthase kinase-3β (GSK-3β) is a multifunctional serine/threonine kinase that plays important roles in the necrosis and apoptosis of cardiomyocytes. Our study aimed to investigate the role of GSK-3β in TP-induced cardiotoxicity. Inhibition of GSK-3β activity by SB 216763, a potent and selective GSK-3 inhibitor, prominently ameliorated the detrimental effects in C57BL/6J mice with TP administration, which was associated with a correction of GSK-3β overactivity. Consistently, in TP-treated H9c2 cells, SB 216763 treatment counteracted GSK-3β overactivity, improved cell viability, and prevented apoptosis by modulating the expression of Bcl-2 family proteins. Mechanistically, GSK-3β interacted with and phosphorylated cyclophilin F (Cyp-F), a key regulator of mitochondrial permeability transition pore (mPTP). GSK-3β inhibition prevented the phosphorylation and activation of Cyp-F, and desensitized mPTP. Our findings suggest that pharmacological targeting of GSK-3β could represent a promising therapeutic strategy for protecting against cardiotoxicity induced by TP. - Highlights: • GSK-3β inhibition ameliorates TP-induced cardiotoxicity in vitro and in vivo. • GSK-3β controls Cyp-F activation, and regulates mPTP and apoptosis in H9c2 cells. • The protective effect is attributed to GSK-3β activity rather than to protein level. • GSK-3β may be a promising target against TP-induced cardiotoxicity.

  11. Tables of double beta decay data

    Energy Technology Data Exchange (ETDEWEB)

    Tretyak, V.I. [AN Ukrainskoj SSR, Kiev (Ukraine)]|[Strasbourg-1 Univ., 67 (France). Centre de Recherches Nucleaires; Zdesenko, Y.G. [AN Ukrainskoj SSR, Kiev (Ukraine)

    1995-12-31

    A compilation of experimental data on double beta decay is presented. The tables contain the most stringent known experimental limits or positive results of 2{beta} transitions of 69 natural nuclides to ground and excited states of daughter nuclei for different channels (2{beta}{sup -}; 2{beta}{sup +}; {epsilon}{beta}{sup +}; 2{epsilon}) and modes (0{nu}; 2{nu}; 0{nu}M) of decay. (authors). 189 refs., 9 figs., 3 tabs.

  12. Thermal Vibrations of Beta-Brass and the Order-Disorder Transition; Vibrations Thermiques dans le Laiton Beta et Transformation Ordre-Desordre; Teplovye kolebaniya beta-latuni i perekhod iz uporyadochennogo sostoyaniya v razuporyadochennoe; Vibraciones Termicas del Laton Beta y Transicion Orden-Desorden

    Energy Technology Data Exchange (ETDEWEB)

    Dolling, G.; Gilat, G. [Chalk River Nuclear Laboratories, Chalk River, ON (Canada)

    1965-04-15

    Observations of normal modes of vibration of the ordered alloy of copper and zinc, {beta}-brass, at 296 Degree-Sign K have been made by means of the coherent one-phonon scattering of slow neutrons from single crystal specimens. The triple-axis crystal spectrometer at the NRU reactor has been used to measure the frequencies of modes propagating along the high-symmetry directions [00{zeta}], [{zeta}{zeta}0], [{zeta}{zeta}{zeta}{zeta}] and [ Vulgar-Fraction-One-Half Vulgar-Fraction-One-Half {zeta}]. The dispersion curves resemble those of a simple body-centred cubic crystal such as Na, except that certain degeneracies are lifted, mainly by reason of the difference between the second nearest neighbour Cu-Cu and Zn-Zn forces. For example, we find two distinct modes of wave vector (0.5, 0.5, 0.5) (in reciprocal lattice units), whose frequencies are (4.21 {+-}0.06) and (4.93 {+-} 0.10) x 10{sup 12} c/s respectively. Interatomic force models which provide a satisfactory description of the 296 Degree-Sign K results are briefly mentioned. Several normal modes have been studied at elevated temperatures, particularly in the vicinity of the order-disorder phase transition at about 727 Degree-Sign K. There are no striking changes in the overall structure of the dispersion curves as a result of the vanishing of the long range order at this temperature, although the various ''splittings'' observed at 296 Degree-Sign K are blurred out into more or less continuous ''bands'' of frequencies. As the temperature rises, the frequencies generally decrease, and the energy widths increase. These changes take place in a smooth manner, except for two longitudinal optic modes, observed at positions (1.27, 1.27, 0) and (1.2, 1.2, 0.2) in reciprocal space, which display sharp increases in energy width at the transition temperature. No reasonable explanation of these effects has yet been found. (author) [French] On a observe les modes normaux de vibration du laiton beta, alliage ordonne de cuivre

  13. BETA SPECTRA. I. Negatrons spectra

    International Nuclear Information System (INIS)

    Grau Malonda, A.; Garcia-Torano, E.

    1978-01-01

    Using the Fermi theory of beta decay, the beta spectra for 62 negatrons emitters have been computed introducing a correction factor for unique forbidden transitions. These spectra are plotted vs. energy, once normal i sed, and tabulated with the related Fermi functions. The average and median energies are calculated. (Author)

  14. Induced nuclear beta decay

    International Nuclear Information System (INIS)

    Reiss, H.R.

    1986-01-01

    Certain nuclear beta decay transitions normally inhibited by angular momentum or parity considerations can be induced to occur by the application of an electromagnetic field. Such decays can be useful in the controlled production of power, and in fission waste disposal

  15. Speculative Betas

    OpenAIRE

    Harrison Hong; David Sraer

    2012-01-01

    We provide a model for why high beta assets are more prone to speculative overpricing than low beta ones. When investors disagree about the common factor of cash-flows, high beta assets are more sensitive to this macro-disagreement and experience a greater divergence-of-opinion about their payoffs. Short-sales constraints for some investors such as retail mutual funds result in high beta assets being over-priced. When aggregate disagreement is low, expected return increases with beta due to r...

  16. Beta-decay rate and beta-delayed neutron emission probability of improved gross theory

    Science.gov (United States)

    Koura, Hiroyuki

    2014-09-01

    A theoretical study has been carried out on beta-decay rate and beta-delayed neutron emission probability. The gross theory of the beta decay is based on an idea of the sum rule of the beta-decay strength function, and has succeeded in describing beta-decay half-lives of nuclei overall nuclear mass region. The gross theory includes not only the allowed transition as the Fermi and the Gamow-Teller, but also the first-forbidden transition. In this work, some improvements are introduced as the nuclear shell correction on nuclear level densities and the nuclear deformation for nuclear strength functions, those effects were not included in the original gross theory. The shell energy and the nuclear deformation for unmeasured nuclei are adopted from the KTUY nuclear mass formula, which is based on the spherical-basis method. Considering the properties of the integrated Fermi function, we can roughly categorized energy region of excited-state of a daughter nucleus into three regions: a highly-excited energy region, which fully affect a delayed neutron probability, a middle energy region, which is estimated to contribute the decay heat, and a region neighboring the ground-state, which determines the beta-decay rate. Some results will be given in the presentation. A theoretical study has been carried out on beta-decay rate and beta-delayed neutron emission probability. The gross theory of the beta decay is based on an idea of the sum rule of the beta-decay strength function, and has succeeded in describing beta-decay half-lives of nuclei overall nuclear mass region. The gross theory includes not only the allowed transition as the Fermi and the Gamow-Teller, but also the first-forbidden transition. In this work, some improvements are introduced as the nuclear shell correction on nuclear level densities and the nuclear deformation for nuclear strength functions, those effects were not included in the original gross theory. The shell energy and the nuclear deformation for

  17. Origins of Beta Tantalum in Sputtered Coatings

    National Research Council Canada - National Science Library

    Mulligan, C

    2001-01-01

    .... Some of the most recent work has attempted to relate the energetics (i.e., atom/ion energy) of the plasma to the alpha right arrow beta transition. It has been shown that the energetics of the plasma can relate to the most crucial sputtering parameters. The most significant feature of the use of plasma energy to explain the alpha right arrow beta transition is that it relates the formation of beta-tantalum to a quantifiable measure.

  18. Study of $\\beta$-delayed neutron decay of $^{8}$He

    CERN Multimedia

    The goal of the present proposal is to study $\\beta$-delayed neutron decay branch of $^{8}$He. The energy spectra of the emitted neutrons will be measured in the energy range of 0.1 – 6 MeV using the VANDLE spectrometer. Using coincident $\\gamma$-ray measurement, components of the spectrum corresponding to transitions to the ground- and first- excited states of $^{7}$Li will be disentangled. The new data will allow us to get a more complete picture of the $\\beta$-decay of $^{8}$He and to clarify the discrepancy between the B(GT) distributions derived from the $\\beta$-decay and $^{8}$He(p, n)$^{8}$Li reaction studies.

  19. Spin-polarized x-ray emission of 3d transition-metal ions : A comparison via K alpha and K beta detection

    NARCIS (Netherlands)

    Wang, Xin; deGroot, F.M.F.; Cramer, SP

    1997-01-01

    This paper demonstrates that spin-polarized x-ray-excitation spectra can be obtained using K alpha emission as well as K beta lines. A spin-polarized analysis of K alpha x-ray emission and the excitation spectra by K alpha detection on a Ni compound is reported. A systematic analysis of the

  20. Beta spectrometry

    International Nuclear Information System (INIS)

    Dryak, P.; Zderadicka, J.; Plch, J.; Kokta, L.; Novotna, P.

    1977-01-01

    For the purpose of beta spectrometry, a semiconductor spectrometer with one Si(Li) detector cooled with liquid nitrogen was designed. Geometrical detection efficiency is about 10% 4 sr. The achieved resolution for 624 keV conversion electrons of sup(137m)Ba is 2.6 keV (FWHM). A program was written in the FORTRAN language for the correction of the deformation of the measured spectra by backscattering in the analysis of continuous beta spectra. The method permits the determination of the maximum energy of the beta spectrum with an accuracy of +-5 keV. (author)

  1. Beta Blockers

    Science.gov (United States)

    ... may not work as effectively for people of African heritage and older people, especially when taken without ... conditions/high-blood-pressure/in-depth/beta-blockers/ART-20044522 . Mayo Clinic Footer Legal Conditions and Terms ...

  2. Majorana neutrino masses and the neutrinoless double-beta decay

    International Nuclear Information System (INIS)

    Faessler, A.

    2006-01-01

    Neutrinoless double-beta decay is forbidden in the Standard Model of electroweak and strong interaction but allowed in most Grand Unified Theories (GUTs). Only if the neutrino is a Majorana particle (identical with its antiparticle) and if it has a mass is neutrinoless double-beta decay allowed. Apart from one claim that the neutrinoless double-beta decay in 76 Ge is measured, one has only upper limits for this transition probability. But even the upper limits allow one to give upper limits for the electron Majorana neutrino mass and upper limits for parameters of GUTs and the minimal R-parity-violating supersymmetric model. One further can give lower limits for the vector boson mediating mainly the right-handed weak interaction and the heavy mainly right-handed Majorana neutrino in left-right symmetric GUTs. For that, one has to assume that the specific mechanism is the leading one for neutrinoless double-beta decay and one has to be able to calculate reliably the corresponding nuclear matrix elements. In the present work, one discusses the accuracy of the present status of calculating of the nuclear matrix elements and the corresponding limits of GUTs and supersymmetric parameters

  3. Data supporting beta-amyloid dimer structural transitions and protein–lipid interactions on asymmetric lipid bilayer surfaces using MD simulations on experimentally derived NMR protein structures

    Directory of Open Access Journals (Sweden)

    Sara Y. Cheng

    2016-06-01

    Full Text Available This data article supports the research article entitled “Maximally Asymmetric Transbilayer Distribution of Anionic Lipids Alters the Structure and interaction with Lipids of an Amyloidogenic Protein Dimer Bound to the Membrane Surface” [1]. We describe supporting data on the binding kinetics, time evolution of secondary structure, and residue-contact maps of a surface-absorbed beta-amyloid dimer protein on different membrane surfaces. We further demonstrate the sorting of annular and non-annular regions of the protein/lipid bilayer simulation systems, and the correlation of lipid-number mismatch and surface area per lipid mismatch of asymmetric lipid membranes.

  4. Double beta decay in gauge theories

    International Nuclear Information System (INIS)

    Vergados, J.D.

    2002-01-01

    Neutrinoless double beta decay is a very important process both from the particle and nuclear physics point of view. From the elementary particle point of view it pops up in almost every model, giving rise among others to the following mechanisms: a) The traditional contributions like the light neutrino mass mechanism as well as the j L - j R leptonic interference (λ and η terms). b) The exotic R-parity violating supersymmetric (SUSY) contributions. From the nuclear physics point of view it is challenging, because: 1) The nuclei, which can undergo double beta decay, have complicated nuclear structure. 2) The energetically allowed transitions are suppressed (exhaust a small part of all the strength). 3) Since in some mechanisms the intermediate particles are very heavy one must cope with the short distance behavior of the transition operators. 4) The intermediate momenta involved are quite high and one has to consider momentum dependent terms of the nucleon current. Taking the above effects into account from the experimental limits on the interesting nuclei A=76, 82, 96, 100, 116, 128, 130, 136 and 150, we have extracted new limits on the various lepton violating parameters. In particular we get a stringent limit on the R-parity violating parameter λ' 111 -4 . (author)

  5. Beta and muon decays

    International Nuclear Information System (INIS)

    Galindo, A.; Pascual, P.

    1967-01-01

    These notes represent a series of lectures delivered by the authors in the Junta de Energia Nuclear, during the Spring term of 1965. They were devoted to graduate students interested in the Theory of Elementary Particles. Special emphasis was focussed into the computational problems. Chapter I is a review of basic principles (Dirac equation, transition probabilities, final state interactions.) which will be needed later. In Chapter II the four-fermion punctual Interaction is discussed, Chapter III is devoted to the study of beta-decay; the main emphasis is given to the deduction of the formulae corresponding to electron-antineutrino correlation, electron energy spectrum, lifetimes, asymmetry of electrons emitted from polarized nuclei, electron and neutrino polarization and time reversal invariance in beta decay. In Chapter IV we deal with the decay of polarized muons with radiative corrections. Chapter V is devoted to an introduction to C.V.C. theory. (Author)

  6. Beta and muon decays

    Energy Technology Data Exchange (ETDEWEB)

    Galindo, A; Pascual, P

    1967-07-01

    These notes represent a series of lectures delivered by the authors in the Junta de Energia Nuclear, during the Spring term of 1965. They were devoted to graduate students interested in the Theory of Elementary Particles. Special emphasis was focussed into the computational problems. Chapter I is a review of basic principles (Dirac equation, transition probabilities, final state interactions.) which will be needed later. In Chapter II the four-fermion punctual Interaction is discussed, Chapter III is devoted to the study of beta-decay; the main emphasis is given to the deduction of the formulae corresponding to electron-antineutrino correlation, electron energy spectrum, lifetimes, asymmetry of electrons emitted from polarized nuclei, electron and neutrino polarization and time reversal invariance in beta decay. In Chapter IV we deal with the decay of polarized muons with radiative corrections. Chapter V is devoted to an introduction to C.V.C. theory. (Author)

  7. Beta spectra. II-Positron spectra

    International Nuclear Information System (INIS)

    Grau, A.; Garcia-Torano, E.

    1981-01-01

    Using the Fermi theory of beta decay, the beta spectra for 30 positron emitters have been computed, introducing a correction factor for unique forbidden transitions. The spectra are ploted vs. energy, once normalised, and tabulated with the related Fermi functions. The average and median energies are calculated. (author)

  8. Trading sulfur dioxide allowances

    International Nuclear Information System (INIS)

    Goldburg, C.B.; Lave, L.B.

    1992-01-01

    The 1990 Clean Air Act is aimed at generators larger than 25 MW, as these are the largest polluters. Market incentives give each source an emissions allocation but also flexibility. If a plant has lower emissions than the target, it can sell the 'surplus' emissions as allowances to plants that fail to meet the target. Only a few trades have occurred to date. Market-based incentives should lower the costs of improving environmental quality significantly. However, currently institutional dificulties hamper implementation

  9. CCAAT/enhancer binding protein beta (C/EBPβ) isoform balance as a regulator of epithelial-mesenchymal transition in mouse mammary epithelial cells

    International Nuclear Information System (INIS)

    Miura, Yuka; Hagiwara, Natsumi; Radisky, Derek C.; Hirai, Yohei

    2014-01-01

    Activation of the epithelial-mesenchymal transition (EMT) program promotes cell invasion and metastasis, and is reversed through mesenchymal-epithelial transition (MET) after formation of distant metastases. Here, we show that an imbalance of gene products encoded by the transcriptional factor C/EBPβ, LAP (liver-enriched activating protein) and LIP (liver-enriched inhibitory protein), can regulate both EMT- and MET-like phenotypic changes in mouse mammary epithelial cells. By using tetracycline repressive LIP expression constructs, we found that SCp2 cells, a clonal epithelial line of COMMA1-D cells, expressed EMT markers, lost the ability to undergo alveolar-like morphogenesis in 3D Matrigel, and acquired properties of benign adenoma cells. Conversely, we found that inducible expression of LAP in SCg6 cells, a clonal fibroblastic line of COMMA1-D cells, began to express epithelial keratins with suppression of proliferation. The overexpression of the C/EBPβ gene products in these COMMA1-D derivatives was suppressed by long-term cultivation on tissue culture plastic, but gene expression was maintained in cells grown on Matrigel or exposed to proteasome inhibitors. Thus, imbalances of C/EBPβ gene products in mouse mammary epithelial cells, which are affected by contact with basement membrane, are defined as a potential regulator of metastatic potential. - Highlights: • We created a temporal imbalance of C/EBPβ gene products in the mammary model cells. • The temporal up-regulation of LIP protein induced EMT-like cell behaviors. • The temporal up-regulation of LAP protein induced MET-like cell behaviors. • Excess amount of C/EBPβ gene products were eliminated by proteasomal-degradation. • Basement membrane components attenuated proteasome-triggered protein elimination

  10. BETA SPECTRA. I. Negatrons spectra; ESPECTROS BETA. I. Espectros simples de negatrones

    Energy Technology Data Exchange (ETDEWEB)

    Grau Malonda, A; Garcia-Torano, E

    1978-07-01

    Using the Fermi theory of beta decay, the beta spectra for 62 negatrons emitters have been computed introducing a correction factor for unique forbidden transitions. These spectra are plotted vs. energy, once normal i sed, and tabulated with the related Fermi functions. The average and median energies are calculated. (Author)

  11. Kinematic shifts of beta -delayed particles as a probe of beta - nu angular correlations

    CERN Document Server

    Clifford, E T H; Evans, H C; Fästermann, T; Hagberg, E; Hardy, J C; Jackson, K P; Koslowsky, V T; Schmeing, H; Schrewe, U J

    1981-01-01

    Beta-delayed particles undergo a kinematic shift in energy due to recoil motion of the daughter nucleus following beta decay. A careful measurement of this energy shift can be used to establish the ratio of vector to axial vector components in beta transitions. Alpha-beta coincidence data for the beta-delayed alpha decay of /sup 20/Na have been obtained. Component ratios for 6 transitions including the superallowed branch are found. Limits on charge dependent mixing with the analogue state are deduced for 5 states in /sup 20/Ne*. For the superallowed branch the axial vector component is found; the polar vector component is deduced and establishes a value for the vector weak coupling constant of G/sub V/=(1.355+or-0.036)*10/sup -49/ erg cm /sup 3/. (13 refs).

  12. Milk Intolerance, Beta-Casein and Lactose.

    Science.gov (United States)

    Pal, Sebely; Woodford, Keith; Kukuljan, Sonja; Ho, Suleen

    2015-08-31

    True lactose intolerance (symptoms stemming from lactose malabsorption) is less common than is widely perceived, and should be viewed as just one potential cause of cows' milk intolerance. There is increasing evidence that A1 beta-casein, a protein produced by a major proportion of European-origin cattle but not purebred Asian or African cattle, is also associated with cows' milk intolerance. In humans, digestion of bovine A1 beta-casein, but not the alternative A2 beta-casein, releases beta-casomorphin-7, which activates μ-opioid receptors expressed throughout the gastrointestinal tract and body. Studies in rodents show that milk containing A1 beta-casein significantly increases gastrointestinal transit time, production of dipeptidyl peptidase-4 and the inflammatory marker myeloperoxidase compared with milk containing A2 beta-casein. Co-administration of the opioid receptor antagonist naloxone blocks the myeloperoxidase and gastrointestinal motility effects, indicating opioid signaling pathway involvement. In humans, a double-blind, randomized cross-over study showed that participants consuming A1 beta-casein type cows' milk experienced statistically significantly higher Bristol stool values compared with those receiving A2 beta-casein milk. Additionally, a statistically significant positive association between abdominal pain and stool consistency was observed when participants consumed the A1 but not the A2 diet. Further studies of the role of A1 beta-casein in milk intolerance are needed.

  13. Milk Intolerance, Beta-Casein and Lactose

    Directory of Open Access Journals (Sweden)

    Sebely Pal

    2015-08-01

    Full Text Available True lactose intolerance (symptoms stemming from lactose malabsorption is less common than is widely perceived, and should be viewed as just one potential cause of cows’ milk intolerance. There is increasing evidence that A1 beta-casein, a protein produced by a major proportion of European-origin cattle but not purebred Asian or African cattle, is also associated with cows’ milk intolerance. In humans, digestion of bovine A1 beta-casein, but not the alternative A2 beta-casein, releases beta-casomorphin-7, which activates μ-opioid receptors expressed throughout the gastrointestinal tract and body. Studies in rodents show that milk containing A1 beta-casein significantly increases gastrointestinal transit time, production of dipeptidyl peptidase-4 and the inflammatory marker myeloperoxidase compared with milk containing A2 beta-casein. Co-administration of the opioid receptor antagonist naloxone blocks the myeloperoxidase and gastrointestinal motility effects, indicating opioid signaling pathway involvement. In humans, a double-blind, randomized cross-over study showed that participants consuming A1 beta-casein type cows’ milk experienced statistically significantly higher Bristol stool values compared with those receiving A2 beta-casein milk. Additionally, a statistically significant positive association between abdominal pain and stool consistency was observed when participants consumed the A1 but not the A2 diet. Further studies of the role of A1 beta-casein in milk intolerance are needed.

  14. Method and apparatus for induced nuclear beta decay

    International Nuclear Information System (INIS)

    Reiss, H.

    1986-01-01

    This invention relates to a method and apparatus for inducing beta decay transition that are normally inhibited by angular momentum or parity considerations. According to one aspect of this invention a method of inducing nuclear beta decay transition comprises providing a medium which includes atomic nuclei that have forbidden beta decay transition in which the initial and final nuclear states do not have the same intrinsic parity or have total angular momenta which differ by more than one quantum unit of angular momentum, and applying to the medium an electromagnetic field which has an intensity sufficient to provide the angular momentum or intrinsic parity necessary to overcome the forbiddenness of the beta decay transition of the atomic nuclei, thereby to induce the beta decay transitions. According to another aspect of this invention an apparatus for inducing beta decay transition comprises a medium which includes atomic nuclei that have forbidden beta decay transitions in which the initial and final nuclear states do not have the same intrinsic parity or have total angular momenta which differ by more than one quantum unit of angular momentum, field producing means for producing an electromagnetic field in the medium and means for energising the field producing means to establish the field at an intensity sufficient to provide the angular momentum or intrinsic parity necessary to overcome the forbiddenness of the beta decay transitions of the atomic nuclei. The energy released in these induced nuclear transition is useful for the controlled production of power. The induced beta dacay transitions are also useful to reduce the halflives of long-lived fission product wastes from conventional nuclear fission power plants

  15. 40 CFR 35.2025 - Allowance and advance of allowance.

    Science.gov (United States)

    2010-07-01

    ... advance of allowance. (a) Allowance. Step 2+3 and Step 3 grant agreements will include an allowance for facilities planning and design of the project and Step 7 agreements will include an allowance for facility... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Allowance and advance of allowance. 35...

  16. Beta decay to the second 2+ excited state of 122Te

    International Nuclear Information System (INIS)

    Hayashi, Takeo; Yamada, Shigeru

    1976-01-01

    The first-forbidden beta transition in Sb-122 was studied by the angular correlation experiment and the beta-spectra. The special precautions were paid for counting the beta particles having energy lower than 750 keV in the beta-gamma angular correlation measurement. The sources of Sb-122 were obtained by irradiating enriched Sb-121 in the Kyoto University reactor. The reduced beta coefficient R(E) was obtained from the angular correlation function. The beta spectrum measurement was performed with a sector type double focusing beta-ray spectrometer. The R(E) values for the beta transitions were analyzed by using the simplex method as used by Manthuruthil and Poirier to compare the angular correlation data with the exact formula given by Morita and Morita. Sets of the nuclear matrix parameters thus obtained show that the condition for the cancellation effect is satisfied in the beta transition. (Kato, T.)

  17. Beta Emission and Bremsstrahlung

    Energy Technology Data Exchange (ETDEWEB)

    Karpius, Peter Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-11-13

    Bremsstrahlung is continuous radiation produced by beta particles decelerating in matter; different beta emitters have different endpoint energies; high-energy betas interacting with high-Z materials will more likely produce bremsstrahlung; depending on the data, sometimes all you can say is that a beta emitter is present.

  18. A Bayesian Panel Data Approach to Explaining Market Beta Dynamics

    NARCIS (Netherlands)

    R. Bauer (Rob); M.M.J.E. Cosemans (Mathijs); R. Frehen (Rik); P.C. Schotman (Peter)

    2008-01-01

    markdownabstractWe characterize the process that drives the market betas of individual stocks by setting up a hierarchical Bayesian panel data model that allows a flexible specification for beta. We show that combining the parametric relationship between betas and conditioning variables specified by

  19. Beta Risk in the Cross-section of Equities

    DEFF Research Database (Denmark)

    Boloorforoosh, Ali; Christoffersen, Peter; Fournier, Mathieu

    on returns and options for a large number of firms we find that allowing for beta risk helps explain the expected returns on low and high beta stocks that are challenging for standard factor models. Overall, we find strong evidence that accounting for beta risk results in better model fit....

  20. Double Beta Decay and Neutrino Masses Accuracy of the Nuclear Matrix Elements

    International Nuclear Information System (INIS)

    Faessler, Amand

    2005-01-01

    The neutrinoless double beta decay is forbidden in the standard model of the electroweak and strong interaction but allowed in most Grand Unified Theories (GUT's). Only if the neutrino is a Majorana particle (identical with its antiparticle) and if it has a mass, the neutrinoless double beta decay is allowed. Apart of one claim that the neutrinoless double beta decay in 76 Ge is measured, one has only upper limits for this transition probability. But even the upper limits allow to give upper limits for the electron Majorana neutrino mass and upper limits for parameters of GUT's and the minimal R-parity violating supersymmetric model. One further can give lower limits for the vector boson mediating mainly the right-handed weak interaction and the heavy mainly right-handed Majorana neutrino in left-right symmetric GUT's. For that one has to assume that the specific mechanism is the leading one for the neutrinoless double beta decay and one has to be able to calculate reliably the corresponding nuclear matrix elements. In the present contribution, one discusses the accuracy of the present status of calculating the nuclear matrix elements and the corresponding limits of GUT's and supersymmetric parameters

  1. Sigma beta decay

    International Nuclear Information System (INIS)

    Newman, D.E.

    1975-01-01

    Describes an experiment to measure beta decays of the sigma particle. Sigmas produced by stopping a K - beam in a liquid hydrogen target decayed in the following reactions: Kp → Σπ; Σ → Neν. The electron and pion were detected by wire spark chambers in a magnetic spectrometer and by plastic scintillators, and were differentiated by a threshold gas Cherenkov counter. The neutron was detected by liquid scintillation counters. The data (n = 3) shell electrons or the highly excited electrons decay first. Instead, it is suggested that when there are two to five electrons in highly excited states immediately after a heavy ion--atom collision the first transitions to occur will be among highly excited Rydberg states in a cascade down to the 4s, 4p, and 3d-subshells. If one of the long lived states becomes occupied by electrons promoted during the collision or by electrons falling from higher levels, it will not decay until after the valence shell decays. LMM rates calculated to test the methods used are compared to previous works. The mixing coefficients are given in terms of the states 4s4p, 45sp+-, and 5s5p. The applicability of Cooper, Fano, and Prats' discussion of the energies and transition rates of doubly excited states is considered

  2. BetaShape: A new code for improved analytical calculations of beta spectra

    Directory of Open Access Journals (Sweden)

    Mougeot Xavier

    2017-01-01

    Full Text Available The new code BetaShape has been developed in order to improve the nuclear data related to beta decays. An analytical model was considered, except for the relativistic electron wave functions, for ensuring fast calculations. Output quantities are mean energies, log ft values and beta and neutrino spectra for single and multiple transitions. The uncertainties from the input parameters, read from an ENSDF file, are propagated. A database of experimental shape factors is included. A comparison over the entire ENSDF database with the standard code currently used in nuclear data evaluations shows consistent results for the vast majority of the transitions and highlights the improvements that can be expected with the use of BetaShape.

  3. Response gene to complement-32 enhances metastatic phenotype by mediating transforming growth factor beta-induced epithelial-mesenchymal transition in human pancreatic cancer cell line BxPC-3

    Directory of Open Access Journals (Sweden)

    Zhu Liang

    2012-03-01

    Full Text Available Abstract Background Response gene to complement-32 (RGC-32 is comprehensively expressed in many kinds of tissues and has been reported to be expressed abnormally in different kinds of human tumors. However, the role of RGC-32 in cancer remains controversial and no reports have described the effect of RGC-32 in pancreatic cancer. The present study investigated the expression of RGC-32 in pancreatic cancer tissues and explored the role of RGC-32 in transforming growth factor-beta (TGF-β-induced epithelial-mesenchymal transition (EMT in human pancreatic cancer cell line BxPC-3. Methods Immunohistochemical staining of RGC-32 and E-cadherin was performed on specimens from 42 patients with pancreatic cancer, 12 with chronic pancreatitis and 8 with normal pancreas. To evaluate the role of RGC-32 in TGF-β-induced EMT in pancreatic cancer cells, BxPC-3 cells were treated with TGF-β1, and RGC-32 siRNA silencing and gene overexpression were performed as well. The mRNA expression and protein expression of RGC-32 and EMT markers such E-cadherin and vimentin were determined by quantitative reverse transcription-PCR (qRT-PCR and western blot respectively. Finally, migration ability of BxPC-3 cells treated with TGF-β and RGC-32 siRNA transfection was examined by transwell cell migration assay. Results We found stronger expression of RGC-32 and higher abnormal expression rate of E-cadherin in pancreatic cancer tissues than those in chronic pancreatitis tissues and normal pancreatic tissues. Immunohistochemical analysis revealed that both RGC-32 positive expression and E-cadherin abnormal expression in pancreatic cancer were correlated with lymph node metastasis and TNM staging. In addition, a significant and positive correlation was found between positive expression of RGC-32 and abnormal expression of E-cadherin. Furthermore, in vitro, we found sustained TGF-β stimuli induced EMT and up-regulated RGC-32 expression in BxPC-3 cells. By means of si

  4. Persistence at low temperature of the P beta' ripple in dipalmitoylphosphatidylcholine multilamellar vesicles containing either glycosphingolipids or cholesterol.

    Science.gov (United States)

    Rock, P; Thompson, T E; Tillack, T W

    1989-03-13

    The disappearance and reappearance of the P beta' ripple in multilamellar liposomes of dipalmitoylphosphatidylcholine (DPPC) has been examined by freeze-etch electron microscopy. The presence of less than 10 mol% of various glycosphingolipids or cholesterol in the liposomes markedly increases the time required for ripple disappearance when the vesicles are cooled from 38 degrees C to 30 degrees C, as compared to the pure phospholipid. Once the ripples have begun to disappear in the two-component vesicles, they do not uniformly reappear until the system is heated above the main transition of DPPC and allowed to cool into the pretransition region. These results suggest that the long time for ripple disappearance in the two-component systems reflects a slow molecular reorganization process which occurs when the systems are forced to change from the P beta' gel to the L beta' gel by a temperature downshift.

  5. Levered and unlevered Beta

    OpenAIRE

    Fernandez, Pablo

    2003-01-01

    We prove that in a world without leverage cost the relationship between the levered beta ( L) and the unlevered beta ( u) is the No-costs-of-leverage formula: L = u + ( u - d) D (1 - T) / E. We also analyze 6 alternative valuation theories proposed in the literature to estimate the relationship between the levered beta and the unlevered beta (Harris and Pringle (1985), Modigliani and Miller (1963), Damodaran (1994), Myers (1974), Miles and Ezzell (1980), and practitioners) and prove that all ...

  6. MetroBeta: Beta Spectrometry with Metallic Magnetic Calorimeters in the Framework of the European Program of Ionizing Radiation Metrology

    Science.gov (United States)

    Loidl, M.; Beyer, J.; Bockhorn, L.; Enss, C.; Györi, D.; Kempf, S.; Kossert, K.; Mariam, R.; Nähle, O.; Paulsen, M.; Rodrigues, M.; Schmidt, M.

    2018-05-01

    MetroBeta is a European project aiming at the improvement of the knowledge of the shapes of beta spectra, both in terms of theoretical calculations and measurements. It is part of a common European program of ionizing radiation metrology. Metallic magnetic calorimeters (MMCs) with the beta emitter embedded in the absorber have in the past proven to be among the best beta spectrometers, in particular for low-energy beta transitions. Within this project, new designs of MMCs optimized for five different beta energy ranges were developed. A new detector module with thermal decoupling of MMC and SQUID chips was designed. An important aspect of the research and development concerns the source/absorber preparation techniques. Four beta spectra with maximum energies ranging from 76 to 709 keV will be measured. Improved theoretical calculation methods and complementary measurement techniques complete the project.

  7. Beta Thalassemia (For Parents)

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Beta Thalassemia KidsHealth / For Parents / Beta Thalassemia What's in this ... Symptoms Diagnosis Treatment Print en español Beta talasemia Thalassemias Thalassemias are a group of blood disorders that ...

  8. Forward-Looking Betas

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Jacobs, Kris; Vainberg, Gregory

    Few issues are more important for finance practice than the computation of market betas. Existing approaches compute market betas using historical data. While these approaches differ in terms of statistical sophistication and the modeling of the time-variation in the betas, they are all backward......-looking. This paper introduces a radically different approach to estimating market betas. Using the tools in Bakshi and Madan (2000) and Bakshi, Kapadia and Madan (2003) we employ the information embedded in the prices of individual stock options and index options to compute our forward-looking market beta...

  9. BetaTPred: prediction of beta-TURNS in a protein using statistical algorithms.

    Science.gov (United States)

    Kaur, Harpreet; Raghava, G P S

    2002-03-01

    beta-turns play an important role from a structural and functional point of view. beta-turns are the most common type of non-repetitive structures in proteins and comprise on average, 25% of the residues. In the past numerous methods have been developed to predict beta-turns in a protein. Most of these prediction methods are based on statistical approaches. In order to utilize the full potential of these methods, there is a need to develop a web server. This paper describes a web server called BetaTPred, developed for predicting beta-TURNS in a protein from its amino acid sequence. BetaTPred allows the user to predict turns in a protein using existing statistical algorithms. It also allows to predict different types of beta-TURNS e.g. type I, I', II, II', VI, VIII and non-specific. This server assists the users in predicting the consensus beta-TURNS in a protein. The server is accessible from http://imtech.res.in/raghava/betatpred/

  10. Measurement of the beta spectrum of the 0/sup -/ (120 keV) state of /sup 16/N

    Energy Technology Data Exchange (ETDEWEB)

    Champagne, A; Beaudoin, G; Hamel, L A; Jeremie, H; Lessard, L

    1988-08-01

    We have measured the beta spectrum of the 0/sup -/ (120 keV, t/sub 1/2/ = 5.25 ..mu..s) state of /sup 16/N. The response function of our detector has been measured, parameterized and then fitted to known spectral shapes taken under conditions close to those in the actual experiment. Using this response function and subtracting a 56 ..mu..s half-life background due to neutron capture in the detector, the measured 0/sup -/ spectrum compares well with the allowed shape for the 0/sup -/ -> 0/sup +/ spectrum plus a small contribution from the allowed 0/sup -/ -> 1/sup -/ transition.

  11. Weak interaction studies from nuclear beta decay

    International Nuclear Information System (INIS)

    Morita, M.

    1981-01-01

    The studies performed at the theoretical nuclear physics division of the Laboratory of Nuclear Studies, Osaka University, are reported. Electron spin density and internal conversion process, nuclear excitation by electron transition, beta decay, weak charged current, and beta-ray angular distributions in oriented nuclei have been studied. The relative intensity of internal conversion electrons for the case in which the radial wave functions of orbital electrons are different for electron spin up and down was calculated. The calculated value was in good agreement with the experimental one. The nuclear excitation following the transition of orbital electrons was studied. The calculated probability of the nuclear excitation of Os 189 was 1.4 x 10 - 7 in conformity with the experimental value 1.7 x 10 - 7 . The second class current and other problems on beta-decay have been extensively studied, and described elsewhere. Concerning weak charged current, the effects of all induced terms, the time component of main axial vector, all partial waves of leptons, Coulomb correction for the electrons in finite size nuclei, and radiative correction were studied. The beta-ray angular distribution for the 1 + -- 0 + transition in oriented B 12 and N 12 was investigated. In this connection, investigation on the weak magnetism to include all higher order corrections for the evaluation of the spectral shape factors was performed. Other works carried out by the author and his collaborators are also explained. (Kato, T.)

  12. An experimental investigation of double beta decay of 100Mo

    International Nuclear Information System (INIS)

    Dougherty, B.L.

    1988-01-01

    New limits on half-lives for several double beta decay modes of 100 Mo were obtained with a novel experimental system which included thin source films interleaved with a coaxial array of windowless silicon detectors. Segmentation and timing information allowed backgrounds originating in the films to be studied in some detail. Dummy films containing 96 Mo were used to assess remaining backgrounds. With 0.1 mole years of 100 Mo data collected, the lower half-life limits at 90% confidence were 2.7 /times/ 10 18 years for decay via the two-neutrino mode, 5.2 /times/10 19 years for decay with the emission of a Majoron, and 1.6 /times/ 10 20 years and 2.2 /times/ 10 21 years for neutrinoless 0 + → 2 + and 0 + → 0 + transitions, respectively. 50 refs., 38 figs., 11 tabs

  13. Beta decay rates of neutron-rich nuclei

    Science.gov (United States)

    Marketin, Tomislav; Huther, Lutz; Petković, Jelena; Paar, Nils; Martínez-Pinedo, Gabriel

    2016-06-01

    Heavy element nucleosynthesis models involve various properties of thousands of nuclei in order to simulate the intricate details of the process. By necessity, as most of these nuclei cannot be studied in a controlled environment, these models must rely on the nuclear structure models for input. Of all the properties, the beta-decay half-lives are one of the most important ones due to their direct impact on the resulting abundance distributions. In this study we present the results of a large-scale calculation based on the relativistic nuclear energy density functional, where both the allowed and the first-forbidden transitions are studied in more than 5000 neutron-rich nuclei. Aside from the astrophysical applications, the results of this calculation can also be employed in the modeling of the electron and antineutrino spectra from nuclear reactors.

  14. Beta decay rates of neutron-rich nuclei

    International Nuclear Information System (INIS)

    Marketin, Tomislav; Petković, Jelena; Paar, Nils; Huther, Lutz; Martínez-Pinedo, Gabriel

    2016-01-01

    Heavy element nucleosynthesis models involve various properties of thousands of nuclei in order to simulate the intricate details of the process. By necessity, as most of these nuclei cannot be studied in a controlled environment, these models must rely on the nuclear structure models for input. Of all the properties, the beta-decay half-lives are one of the most important ones due to their direct impact on the resulting abundance distributions. In this study we present the results of a large-scale calculation based on the relativistic nuclear energy density functional, where both the allowed and the first-forbidden transitions are studied in more than 5000 neutron-rich nuclei. Aside from the astrophysical applications, the results of this calculation can also be employed in the modeling of the electron and antineutrino spectra from nuclear reactors.

  15. Beta decay rates of neutron-rich nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Marketin, Tomislav, E-mail: marketin@phy.hr; Petković, Jelena; Paar, Nils [Department of Physics, Faculty of Science, University of Zagreb, 10000 Zagreb (Croatia); Huther, Lutz [Institut für Kernphysik (Theoriezentrum), Technische Universität Darmstadt, 64289 Darmstadt (Germany); Martínez-Pinedo, Gabriel [Institut für Kernphysik (Theoriezentrum), Technische Universität Darmstadt, 64289 Darmstadt (Germany); GSI Helmholtzzentrum für Schwerioneneforschung, Planckstraße 1, 64291 Darmstadt (Germany)

    2016-06-21

    Heavy element nucleosynthesis models involve various properties of thousands of nuclei in order to simulate the intricate details of the process. By necessity, as most of these nuclei cannot be studied in a controlled environment, these models must rely on the nuclear structure models for input. Of all the properties, the beta-decay half-lives are one of the most important ones due to their direct impact on the resulting abundance distributions. In this study we present the results of a large-scale calculation based on the relativistic nuclear energy density functional, where both the allowed and the first-forbidden transitions are studied in more than 5000 neutron-rich nuclei. Aside from the astrophysical applications, the results of this calculation can also be employed in the modeling of the electron and antineutrino spectra from nuclear reactors.

  16. Beta decay rates of neutron-rich nuclei

    International Nuclear Information System (INIS)

    Marketin, Tomislav; Huther, Lutz; Martínez-Pinedo, Gabriel

    2015-01-01

    Heavy element nucleosynthesis models involve various properties of thousands of nuclei in order to simulate the intricate details of the process. By necessity, as most of these nuclei cannot be studied in a controlled environment, these models must rely on the nuclear structure models for input. Of all the properties, the beta-decay half-lives are one of the most important ones due to their direct impact on the resulting abundance distributions. Currently, a single large-scale calculation is available based on a QRPA calculation with a schematic interaction on top of the Finite Range Droplet Model. In this study we present the results of a large-scale calculation based on the relativistic nuclear energy density functional, where both the allowed and the first-forbidden transitions are studied in more than 5000 neutron-rich nuclei

  17. Beta decay rates of neutron-rich nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Marketin, Tomislav, E-mail: marketin@phy.hr [Department of Physics, Faculty of Science, University of Zagreb, 10000 Zagreb (Croatia); Huther, Lutz [Institut für Kernphysik (Theoriezentrum), Technische Universität Darmstadt, 64289 Darmstadt (Germany); Martínez-Pinedo, Gabriel [Institut für Kernphysik (Theoriezentrum), Technische Universität Darmstadt, 64289 Darmstadt (Germany); GSI Helmholtzzentrum für Schwerioneneforschung, Planckstraße 1, 64291 Darmstadt (Germany)

    2015-10-15

    Heavy element nucleosynthesis models involve various properties of thousands of nuclei in order to simulate the intricate details of the process. By necessity, as most of these nuclei cannot be studied in a controlled environment, these models must rely on the nuclear structure models for input. Of all the properties, the beta-decay half-lives are one of the most important ones due to their direct impact on the resulting abundance distributions. Currently, a single large-scale calculation is available based on a QRPA calculation with a schematic interaction on top of the Finite Range Droplet Model. In this study we present the results of a large-scale calculation based on the relativistic nuclear energy density functional, where both the allowed and the first-forbidden transitions are studied in more than 5000 neutron-rich nuclei.

  18. Roles of configuration mixing and exchange currents in nuclear magnetic moments and beta decays. Chapter 17

    International Nuclear Information System (INIS)

    Arima, A.; Hyuga, H.

    1979-01-01

    The authors review systematically several important mechanisms which affect magnetic moments, magnetic dipole transitions and allowed beta-decays. They are first order configuration mixing, second order configuration mixing, the Sachs moment and other exchange magnetic moments, the contribution of the Sachs moment and other exchange magnetic moments with first order configuration mixing. It is shown that first order configuration mixing and the Sachs moment are important for heavy nuclei, and that all the effects except first order mixing are important for light nuclei. (Auth.)

  19. The beta-decay of 48Mn: improved data on Gamow-Teller quenching

    International Nuclear Information System (INIS)

    Szerypo, J.; Bazin, D.; Brown, B.A.

    1991-01-01

    Beta-decay studies of very proton-rich nuclides allow to investigate the phenomenon of quenching of Gamow-Teller transitions. A presentation of the experimental techniques is followed by the discussion of preliminray results of the measurements in comparison to shell-model calculations. A corresponding reinvestigation is discussed. A mass-separated 48 Mn beam was used from 12 C( 40 Ca,p3n) reactions. The 48 Mn decay spectroscopy was performed simultaneously in two beam lines of the mass separator. (G.P.) 13 refs.; 2 figs

  20. Electromagnetically induced nuclear beta decay calculated by a Green's function method

    International Nuclear Information System (INIS)

    Reiss, H.R.

    1984-01-01

    The transition probability for enhancement of forbidden nuclear beta decay by an applied plane-wave electromagnetic field is calculated in a nonrelativistic spinless approximation by a Green's function method. The calculation involves a stationary-phase approximation. The stationary phase points in the presence of an intense field are located in very different positions than they are in the field-free case. In order-of-magnitude terms, the results are completely consistent with an earlier, much more complete wave-function calculation which includes spin and relativistic effects. Both the present Green's function calculation and the earlier wave function calculation give electromagnetic contributions in first-forbidden nuclear beta decay matrix elements which are of order (R 0 /lambda-dash-bar/sub C/) 2 with respect to allowed decays, where R 0 is the nuclear radius and lambda-dash-bar/sub C/ is the electron Compton wavelength

  1. Study of 193Os beta- decay

    International Nuclear Information System (INIS)

    Zahn, Guilherme Soares

    2006-01-01

    In this work, the excited levels of 193 Ir populated by the beta - decay of 193 Os (T 1/2 ∼ 30h) were investigated. For that purpose, ∼ 5 mg samples of 99%-enriched 192 Os were irradiated under a thermal neutron flux of ∼ 10 12 s -1 and then analysed both using single gamma spectroscopy and a 4-detector multi parametric acquisition facility, which provided data for both a gamma gamma coincidence analysis and a directional angular correlation gamma gamma (θ ) study. From these data, 28 transitions were added to this decay scheme, 11 of which were previously known from nuclear reactions and 17 observed for the first time. Eight excited levels were also added to the decay scheme, 3 of which were known from nuclear reaction studies - the remaining 5 are suggested for the first time. Moreover, it was possible to confirm suspicions found in reference that the levels at 848.93 keV and 849.093 keV are indeed the same; it was also possible to confirm the existence of an excited level at 806.9 keV, which had been inferred, but not experimentally confirmed in beta decay studies to date. The angular correlation analysis allowed for the definition of the spin of the excited level at 874 keV as 5/2 +; moreover, the results showed a 79% probability that the spin of the 1078 keV level is 5/2/'-, and also restricted the spin possibilities for the new excited level at 960 keV to two values (1/2 or 3/2). It was also possible to measure the multipolarity mixing ratio (δ Ln+1 /L n ) for 43 transitions - 19 of them for the first time and most of the others with a better precision than previously known. Finally, an attempt was made to understand the low-lying levels structure for this nucleus using a theoretical model, which reproduced the ground state and the two lowest-lying excited levels in 193 Ir. (author)

  2. Betting Against Beta

    DEFF Research Database (Denmark)

    Frazzini, Andrea; Heje Pedersen, Lasse

    We present a model with leverage and margin constraints that vary across investors and time. We find evidence consistent with each of the model’s five central predictions: (1) Since constrained investors bid up high-beta assets, high beta is associated with low alpha, as we find empirically for U...... of the BAB factor is low; (4) Increased funding liquidity risk compresses betas toward one; (5) More constrained investors hold riskier assets........S. equities, 20 international equity markets, Treasury bonds, corporate bonds, and futures; (2) A betting-against-beta (BAB) factor, which is long leveraged low beta assets and short high-beta assets, produces significant positive risk-adjusted returns; (3) When funding constraints tighten, the return...

  3. Roughing up Beta

    DEFF Research Database (Denmark)

    Bollerslev, Tim; Li, Sophia Zhengzi; Todorov, Viktor

    -section. An investment strategy that goes long stocks with high jump betas and short stocks with low jump betas produces significant average excess returns. These higher risk premiums for the discontinuous and overnight market betas remain significant after controlling for a long list of other firm characteristics......Motivated by the implications from a stylized equilibrium pricing framework, we investigate empirically how individual equity prices respond to continuous, or \\smooth," and jumpy, or \\rough," market price moves, and how these different market price risks, or betas, are priced in the cross......-section of expected returns. Based on a novel highfrequency dataset of almost one-thousand individual stocks over two decades, we find that the two rough betas associated with intraday discontinuous and overnight returns entail significant risk premiums, while the intraday continuous beta is not priced in the cross...

  4. Majorana neutrinos and double beta-decay

    International Nuclear Information System (INIS)

    Shchepkin, M.G.

    1986-01-01

    Problem, related to neutrino mass and lepton charge L conservation is briefly discussed. A possibility to experimentally test L conservation in different processes and to produce limitations for neutrino mass in double beta-decay processes is considered. Planned experiments on studying the double neutrinoless (2β) beta-decays and searching 2β(2ν)-decays, permitted by the conservation laws, are discussed. It is stressed, that comparison of the existing theoretical predictions of 2β(2ν)-decay probability with experimental results will make it possible to choose the most adequate approach to the calculation of double β-transition nuclear amplitudes

  5. Precision measurements in nuclear beta decay

    Energy Technology Data Exchange (ETDEWEB)

    Naviliat-Cuncic, Oscar, E-mail: naviliat@nscl.msu.edu [Michigan State University, National Superconducting Cyclotron Laboratory and Department of Physics and Astronomy (United States)

    2013-03-15

    Precision measurements in nuclear beta decay provide sensitive means to determine the fundamental coupling of charged fermions to weak bosons and to test discrete symmetries in the weak interaction. The main motivation of such measurements is to find deviations from Standard Model predictions as possible indications of new physics. I focus here on two topics related to precision measurements in beta decay, namely: (i) the determination of the V{sub ud} element of the Cabibbo-Kobayashi-Maskawa quark mixing matrix from nuclear mirror transitions and (ii) selected measurements of time reversal violating correlations in nuclear and neutron decays. These topics complement those presented in other contributions to this conference.

  6. Beta limits for ETF

    International Nuclear Information System (INIS)

    Helton, F.J.; Miller, R.L.

    1982-01-01

    ETF (Engineering Test Facility) one-dimensional transport simulations indicate that a volume-average beta of 4% is required for ignition. It is therefore important that theoretical beta limits, determined by requiring equilibria to be stable to all ideal modes, exceed 4%. This paper documents an ideal MHD analysis wherein it is shown that, with appropriate plasma cross-sectional shape and current profile optimization, operation near 5% is possible. The critical beta value, however, depends on the functional form used for ff', which suggests that higher critical betas could be achieved by directly optimizing the safety factor profile. (author)

  7. Induced Double-Beta Processes in Electron Fluxes as Resonance Reactions in Weak Interaction

    International Nuclear Information System (INIS)

    Gaponov, Yu.V.

    2004-01-01

    A theory of induced double-beta processes in electron beams is developed. It is shown that a resonance mechanism of the excitation of the ground state of an intermediate nucleus is realized in them, this mechanism being described in the single-state-dominance approximation, where the process in question is broken down into two stages, the excitation of a dominant state and its decay. This approximation is valid irrespective of the features of this state, both for allowed (for a 1 + state of the intermediate nucleus) and for forbidden transitions. An analysis of the resonance mechanism reveals that its inclusion in double-beta-decay processes requires introducing additional diagrams that describe the gamma decay of virtual intermediate states. The inclusion of such corrections may lead to a decrease in the expected half-life and to a change in the beta spectrum. Effects associated with the interference between the two stages of a double-beta process are estimated, and it is shown that their influence can be significant if the time interval between these stages is less than or on the order of the lifetime of the dominant state

  8. Beta-energy averaging and beta spectra

    International Nuclear Information System (INIS)

    Stamatelatos, M.G.; England, T.R.

    1976-07-01

    A simple yet highly accurate method for approximately calculating spectrum-averaged beta energies and beta spectra for radioactive nuclei is presented. This method should prove useful for users who wish to obtain accurate answers without complicated calculations of Fermi functions, complex gamma functions, and time-consuming numerical integrations as required by the more exact theoretical expressions. Therefore, this method should be a good time-saving alternative for investigators who need to make calculations involving large numbers of nuclei (e.g., fission products) as well as for occasional users interested in restricted number of nuclides. The average beta-energy values calculated by this method differ from those calculated by ''exact'' methods by no more than 1 percent for nuclides with atomic numbers in the 20 to 100 range and which emit betas of energies up to approximately 8 MeV. These include all fission products and the actinides. The beta-energy spectra calculated by the present method are also of the same quality

  9. High beta tokamaks

    International Nuclear Information System (INIS)

    Dory, R.A.; Berger, D.P.; Charlton, L.A.; Hogan, J.T.; Munro, J.K.; Nelson, D.B.; Peng, Y.K.M.; Sigmar, D.J.; Strickler, D.J.

    1978-01-01

    MHD equilibrium, stability, and transport calculations are made to study the accessibility and behavior of ''high beta'' tokamak plasmas in the range β approximately 5 to 15 percent. For next generation devices, beta values of at least 8 percent appear to be accessible and stable if there is a conducting surface nearby

  10. Sorting out Downside Beta

    NARCIS (Netherlands)

    G.T. Post (Thierry); P. van Vliet (Pim); S.D. Lansdorp (Simon)

    2009-01-01

    textabstractDownside risk, when properly defined and estimated, helps to explain the cross-section of US stock returns. Sorting stocks by a proper estimate of downside market beta leads to a substantially larger cross-sectional spread in average returns than sorting on regular market beta. This

  11. Betting against Beta

    DEFF Research Database (Denmark)

    Frazzini, Andrea; Heje Pedersen, Lasse

    2014-01-01

    We present a model with leverage and margin constraints that vary across investors and time. We find evidence consistent with each of the model's five central predictions: (1) Because constrained investors bid up high-beta assets, high beta is associated with low alpha, as we find empirically...

  12. Genetics Home Reference: beta thalassemia

    Science.gov (United States)

    ... Facebook Twitter Home Health Conditions Beta thalassemia Beta thalassemia Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Beta thalassemia is a blood disorder that reduces the production ...

  13. Assessing the Implications of Allowing Transgender Personnel to Serve Openly

    Science.gov (United States)

    2016-01-01

    Openly? There are 18 countries that allow transgender personnel to serve openly in their mili- taries: Australia, Austria, Belgium, Bolivia , Canada...clinical and cultural competence for the proper care of transgender patients. Surgical procedures quite similar to those used for gender transition...tries that allow transgender personnel to serve openly in their militaries: Austra- lia, Austria, Belgium, Bolivia , Canada, Czech Republic, Denmark

  14. Rapid synthesis of beta zeolites

    Science.gov (United States)

    Fan, Wei; Chang, Chun -Chih; Dornath, Paul; Wang, Zhuopeng

    2015-08-18

    The invention provides methods for rapidly synthesizing heteroatom containing zeolites including Sn-Beta, Si-Beta, Ti-Beta, Zr-Beta and Fe-Beta. The methods for synthesizing heteroatom zeolites include using well-crystalline zeolite crystals as seeds and using a fluoride-free, caustic medium in a seeded dry-gel conversion method. The Beta zeolite catalysts made by the methods of the invention catalyze both isomerization and dehydration reactions.

  15. Beta : The Good, the Bad, and the Ugly

    NARCIS (Netherlands)

    Driessen, Joost; van Zundert, J.

    2017-01-01

    This paper decomposes aggregate and individual stock returns into cash flow news, interest rate news, and risk premium news. We then extend the “good beta, bad beta” approach of Campbell and Vuolteenaho (2004) by allowing for a third beta: exposure to interest rate news. Using various stock

  16. Development of new microencapsulated beta emitters for internal radiotherapy

    International Nuclear Information System (INIS)

    Perdrisot, R.; Monteil, J.; Le Jeune, J.J.; Pouliquen, D.; Jallet, P.; Beau, P.; Lepape, A.

    1993-01-01

    We have developed new microencapsulated beta emitter radiotracers which could be used in nuclear medicine for selective internal radiotherapy. Their efficacy was evaluated on B16 melanoma tumor model in mice, using phosphorus 31 spectroscopy. This kind of tracer would allow a precise targetting of beta irradiation

  17. 76 FR 70883 - Clothing Allowance

    Science.gov (United States)

    2011-11-16

    ... prescription skin cream for the ``face, neck, hands, arms, or any area not covered by clothing may come into... the clothing or outergarment due to a second appliance or medication.'' This language will clarify that a second clothing allowance may be paid when a second appliance and/or medication increases the...

  18. A gene encoding the major beta tubulin of the mitotic spindle in Physarum polycephalum plasmodia

    Energy Technology Data Exchange (ETDEWEB)

    Burland, T.G.; Paul, E.C.A.; Oetliker, M.; Dove, W.F.

    1988-03-01

    The multinucleate plasmodium of Physarum polycephalum is unusual among eucaryotic cells in that it uses tubulins only in mitotic-spindle microtubules; cytoskeletal, flagellar, and centriolar microtubules are absent in this cell type. The authors identified a ..beta..-tubulin cDNA clone, ..beta..105, which is shown to correspond to the transcript of the betC ..beta..-tubulin locus and to encode ..beta..2 tubulin, the ..beta.. tubulin expressed specifically in the plasmodium and used exclusively in the mitotic spindle. Physarum amoebae utilize tubulins in the cytoskeleton, centrioles, and flagella, in addition to the mitotic spindle. Sequence analysis shows that ..beta..2 tubulin is only 83% identical to the two ..beta.. tubulins expressed in amoebae. This compares with 70 to 83% identity between Physarum ..beta..2 tubulin and the ..beta.. tubulins of yeasts, fungi, alga, trypanosome, fruit fly, chicken, and mouse. On the other hand, Physarum ..beta..2 tubulin is no more similar to, for example, Aspergillus ..beta.. tubulins than it is to those of Drosophila melanogaster or mammals. Several eucaryotes express at least one widely diverged ..beta.. tubulin as well as one or more ..beta.. tubulins that conform more closely to a consensus ..beta..-tubulin sequence. The authors suggest that ..beta..-tubulins diverge more when their expression pattern is restricted, especially when this restriction results in their use in fewer functions. This divergence among ..beta.. tubulins could have resulted through neutral drift. For example, exclusive use of Physarum ..beta..2 tubulin in the spindle may have allowed more amino acid substitutions than would be functionally tolerable in the ..beta.. tubulins that are utilized in multiple microtubular organelles. Alternatively, restricted use of ..beta.. tubulins may allow positive selection to operate more freely to refine ..beta..-tubulin function.

  19. Tables of double beta decay data

    International Nuclear Information System (INIS)

    Tretyak, V.I.

    1995-01-01

    A compilation of experimental data on double beta decay is presented. The tables contain the most stringent known experimental limits or positive results of 2β transitions of 69 natural nuclides to ground and excited states of daughter nuclei for different channels (2β - ; 2β + ; εβ + ; 2ε) and modes (0ν; 2ν; 0νM) of decay. (authors). 189 refs., 9 figs., 3 tabs

  20. Beta particle measurement fundamentals

    International Nuclear Information System (INIS)

    Alvarez, J.L.

    1986-01-01

    The necessary concepts for understanding beta particle behavior are stopping power, range, and scattering. Dose as a consequence of beta particle interaction with tissue can be derived and explained by these concepts. Any calculations of dose, however, assume or require detailed knowledge of the beta spectrum at the tissue depth of calculation. A rudimentary knowledge of the incident spectrum can be of use in estimating dose, interpretating dose measuring devices and designing protection. The stopping power and range based on the csda will give a conservative estimate in cases of protection design, as scattering will reduce the range. Estimates of dose may be low because scattering effects were neglected

  1. Surfaces allowing for fractional statistics

    International Nuclear Information System (INIS)

    Aneziris, Charilaos.

    1992-07-01

    In this paper we give a necessary condition in order for a geometrical surface to allow for Abelian fractional statistics. In particular, we show that such statistics is possible only for two-dimentional oriented surfaces of genus zero, namely the sphere S 2 , the plane R 2 and the cylindrical surface R 1 *S 1 , and in general the connected sum of n planes R 2 -R 2 -R 2 -...-R 2 . (Author)

  2. $\\beta$ decay of $^{47}$Ar

    CERN Document Server

    Weissman, L; Bergmann, U C; Brown, B A; Catherall, R; Cederkäll, J; Dillmann, I; Hallmann, O; Fraile-Prieto, L M; Franchoo, S; Gaudefroy, L; Köster, U; Kratz, K L; Pfeiffer, B; Sorlin, O; 10.1103/PhysRevC.70.024304

    2004-01-01

    Information on beta -decay properties of neutron-rich /sup 47/Ar was obtained at the ISOLDE facility at CERN using isobaric selectivity. This was achieved by a combination of a plasma-ion source with a cooled transfer line and subsequent mass separation. A doubly charged beam was used in order to improve the signal-to-background ratio associated with multi-charged noble gas fission products. The identification of the /sup 47/Ar gamma -ray transitions was performed by comparing the spectra obtained from direct proton bombardment of the target and of the neutron converter. New excited levels in the daughter /sup 47/K nucleus corresponding to the negative-parity states were observed. The obtained data are compared to the result of large-scale shell model calculations and quasiparticle random-phase approximation predictions. (29 refs).

  3. On the nuclear double beta decay: microscopic description

    International Nuclear Information System (INIS)

    Civitarese, Osvaldo

    1989-01-01

    This paper is devoted to the discussion of some problems related with microscopic descriptions of the nuclear double beta decay. It has been organized in the following order: 1) Review of the experimental situation; 2) Brief discussion of the theoretical aspects related to the current algebra, weak interaction, neutrino and majoron's status and 3) Elements of the standard nuclear theory involved in the calculation of transition densities for the nuclear double beta decay. (Author) [es

  4. Neutrinoless double beta decay

    Indian Academy of Sciences (India)

    2012-10-06

    Oct 6, 2012 ... Anyhow, the 'multi-isotope' ansatz is needed to compensate for matrix element ... The neccessary half-life requirement to touch this ... site energy depositions (like double beta decay) and multiple site interactions (most of.

  5. Beta-Carotene

    Science.gov (United States)

    ... disease (COPD). It is also used to improve memory and muscle strength. Some people use beta-carotene ... to reduce the chance of death and night blindness during pregnancy, as well as diarrhea and fever ...

  6. Double beta decay: experiments

    International Nuclear Information System (INIS)

    Fiorini, Ettore

    2006-01-01

    The results obtained so far and those of the running experiments on neutrinoless double beta decay are reviewed. The plans for second generation experiments, the techniques to be adopted and the expected sensitivities are compared and discussed

  7. Emission allowances stall in marketplace

    International Nuclear Information System (INIS)

    Malec, W.F.

    1993-01-01

    Misinformation and public misunderstanding have given emissions trading a bad reputation in the public marketplace, says William F. Malec, executive vice president of the Tennessee Valley Authority (TVA), in Knoxville, Tennessee. Media coverage of a May 1992 emissions-allowance trade between TVA and Wisconsin Power and Light open-quotes focused on the agreement's pollution-trading aspects, not its overall potential economic and environmental benefits,close quotes Malec says. Such negative portrayal of TVA's transaction sparked severe public criticism and charges that emissions trading gives utilities the right to pollute. open-quotes The fact is that TVA sought the emissions-trading agreement as a means to reduce overall emissions in the most cost-effective way,close quotes Malec explains. Emissions trading allows a company with emission levels lower than clean-air standards to earn open-quotes credits.close quotes These credits then may be purchased by a company with emission levels that exceed federal standards. Under this arrangement, the environment is protected and companies that buy credits save money because they do not have to purchase expensive emissions-control devices or reduce their production levels. Malec says TVA decided to enter into the emissions-allowance market, not only to cut costs, but also to publicize the existence and benefits of emissions trading. However, TVA's experience proves that open-quotes people will not accept what they do not understand,close quotes concludes Malec, open-quotes especially when complex environmental issues are involved.close quotes

  8. Thermoreflectance characterization of beta-Ga2O3 thin-film nanostrips.

    Science.gov (United States)

    Ho, Ching-Hwa; Tseng, Chiao-Yeh; Tien, Li-Chia

    2010-08-02

    Nanostructure of beta-Ga(2)O(3) is wide-band-gap material with white-light-emission function because of its abundance in gap states. In this study, the gap states and near-band-edge transitions in beta-Ga(2)O(3) nanostrips have been characterized using temperature-dependent thermoreflectance (TR) measurements in the temperature range between 30 and 320 K. Photoluminescence (PL) measurements were carried to identify the gap-state transitions in the beta-Ga(2)O(3) nanostrips. Experimental analysis of the TR spectra revealed that the direct gap (E(0)) of beta-Ga(2)O(3) is 4.656 eV at 300 K. There are a lot of gap-state and near-band-edge (GSNBE) transitions denoted as E(D3), E(W1), E(W2), E(W3), E(D2), EDBex, E(DB), E(D1), E(0), and E(0)' can be detected in the TR and PL spectra at 30 K. Transition origins for the GSNBE features in the beta-Ga(2)O(3) nanostrips are respectively evaluated. Temperature dependences of transition energies of the GSNBE transitions in the beta-Ga(2)O(3) nanostrips are analyzed. The probable band scheme for the GSNBE transitions in the beta-Ga(2)O(3) nanostrips is constructed.

  9. {beta} - amyloid imaging probes

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Jae Min [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2007-04-15

    Imaging distribution of {beta} - amyloid plaques in Alzheimer's disease is very important for early and accurate diagnosis. Early trial of the {beta} -amyloid plaques includes using radiolabeled peptides which can be only applied for peripheral {beta} - amyloid plaques due to limited penetration through the blood brain barrier (BBB). Congo red or Chrysamine G derivatives were labeled with Tc-99m for imaging {beta} - amyloid plaques of Alzheimer patient's brain without success due to problem with BBB penetration. Thioflavin T derivatives gave breakthrough for {beta} - amyloid imaging in vivo, and a benzothiazole derivative [C-11]6-OH-BTA-1 brought a great success. Many other benzothiazole, benzoxazole, benzofuran, imidazopyridine, and styrylbenzene derivatives have been labeled with F-18 and I-123 to improve the imaging quality. However, [C-11]6-OH-BTA-1 still remains as the best. However, short half-life of C-11 is a limitation of wide distribution of this agent. So, it is still required to develop an Tc-99m, F-18 or I-123 labeled agent for {beta} - amyloid imaging agent.

  10. Targeting of beta 1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells

    NARCIS (Netherlands)

    Dickreuter, E.; Eke, I.; Krause, M.; Borgmann, K.; van Vugt, M. A.; Cordes, N.

    2016-01-01

    beta 1 Integrin-mediated cell-extracellular matrix interactions allow cancer cell survival and confer therapy resistance. It was shown that inhibition of beta 1 integrins sensitizes cells to radiotherapy. Here, we examined the impact of beta 1 integrin targeting on the repair of radiation-induced

  11. $\\beta$-delayed neutron spectroscopy of $^{130-132}$ Cd isotopes with the ISOLDE decay station and the VANDLE array

    CERN Multimedia

    We propose to use the new ISOLDE decay station and the neutron detector VANDLE to measure the $\\beta$-delayed neutron emission of N=82-84 $^{130-132}$Cd isotopes. The large delayed neutron emission probability observed in a previous ISOLDE measurement is indicative of the Gamow-Teller transitions due to the decay of deep core neutrons. Core Gamow-Teller decay has been experimentally proven in the $^{78}$Ni region for the N>50 nuclei using the VANDLE array. The spectroscopic measurement of delayed neutron emission along the cadmium isotopic chain will allow us to track the evolution of the single particle states and the shell gap.

  12. Upside and downside beta portfolio construction: A different approach to risk measurement and portfolio construction

    Directory of Open Access Journals (Sweden)

    Austin Guy

    2015-11-01

    Full Text Available Traditional financial measurements of risk are limited to variance-based methodologies. The most common measurement tool is beta. The beta calculation, however, is directionally agnostic and relies on the assumption of a normal distribution. This is a poor metric by which risk is measured, and is incomplete. The ability to break down beta into Upside and Downside beta allows investors the ability to more intelligently build risk into a portfolio. Using three-year trailing betas may also allow investors the ability to benefit from mean reversion and generate excess returns on a risk-adjusted basis.

  13. Boosted beta regression.

    Directory of Open Access Journals (Sweden)

    Matthias Schmid

    Full Text Available Regression analysis with a bounded outcome is a common problem in applied statistics. Typical examples include regression models for percentage outcomes and the analysis of ratings that are measured on a bounded scale. In this paper, we consider beta regression, which is a generalization of logit models to situations where the response is continuous on the interval (0,1. Consequently, beta regression is a convenient tool for analyzing percentage responses. The classical approach to fit a beta regression model is to use maximum likelihood estimation with subsequent AIC-based variable selection. As an alternative to this established - yet unstable - approach, we propose a new estimation technique called boosted beta regression. With boosted beta regression estimation and variable selection can be carried out simultaneously in a highly efficient way. Additionally, both the mean and the variance of a percentage response can be modeled using flexible nonlinear covariate effects. As a consequence, the new method accounts for common problems such as overdispersion and non-binomial variance structures.

  14. Gamow-teller transitions: progress and problems

    International Nuclear Information System (INIS)

    Walter, G.

    1994-01-01

    The determination of the Gamow-Teller (GT) matrix elements from beta-decay and charge exchange reactions has led to a series of discoveries concerning the structure of the nucleus and the properties of spin-isospin transitions in nuclei. The study of GT distribution and strength, either by charge exchange or weak decay, provides excellent tests for nuclear models as these parameters are extremely sensitive to the details of nuclear structure. Recent improvements of these models have reduced, for the most part, differences between experiment and theory, allowing in turn a more reliable estimate of weak decay rates in stellar matter. A better understanding of the 'missing strength' and of the failure of many experiments to detect the strength that is present have also been obtained. Recently, it appears also that weak decay studies in selected region (proton or neutron rich) of the N-Z plane give access to the GT giant resonance. (J.S.). 65 refs., 10 figs

  15. $\\beta$-delayed neutrons from oriented $^{137,139}$I and $^{87,89}$Br nuclei

    CERN Multimedia

    We propose a world-first measurement of the angular distribution of $\\beta$‐delayed n and $\\gamma$-radiation from oriented $^{137, 139}$I and $^{87,89}$Br nuclei, polarised at low temperature at the NICOLE facility. $\\beta$­-delayed neutron emission is an increasingly important decay mechanism as the drip line is approached and its detailed understanding is essential to phenomena as fundamental as the r‐process and practical as the safe operation of nuclear power reactors. The experiments offer sensitive tests of theoretical input concerning the allowed and first­‐forbidden $\\beta$‐decay strength, the spin-density of neutron emitting states and the partial wave barrier penetration as a function of nuclear deformation. In $^{137}$I and $^{87}$Br the decay feeds predominantly the ground state of the daughters $^{136}$Xe and $^{86}$Kr whereas in $^{139}$I and $^{89}$Br we will explore the use of n-$\\gamma$- coincidence to study neutron transitions to the first and second excited states in the daughters...

  16. $\\beta$-delayed neutrons from oriented $^{137,139}$I and $^{87,89}$Br nuclei

    CERN Document Server

    Grzywacz, Robert; Stone, Nicholas; Köster, Ulli; Singh, Barlaj; Bingham, Carrol; Gaulard, S; Kolos, Karolina; Madurga, Miguel; Nikolov, J; Otsubo, T; Roccia, S; Veskovic, Miroslav; Walker, Phil; Walters, William

    2013-01-01

    We propose a world-­‐first measurement of the angular distribution of $\\beta$-­‐delayed n and $\\gamma$- radiation from oriented $^{137, 139}$I and $^{87,89}$Br nuclei, polarised at low temperature at the NICOLE facility. $\\beta$-­‐delayed neutron emission is an increasingly important decay mechanism as the drip line is approached and its detailed understanding is essential to phenomena as fundamental as the r‐process and practical as the safe operation of nuclear power reactors. The experiments offer sensitive tests of theoretical input concerning the allowed and first-­‐forbidden $\\beta$‐decay strength, the spin-­‐density of neutron emitting states and the partial wave barrier penetration as a function of nuclear deformation. In $^{137}$I and $^{87}$Br the decay feeds predominantly the ground state of the daughters $^{136}$Xe and $^{86}$Kr whereas in $^{139}$I and $^{89}$Br we will explore the use of n-$\\gamma$- coincidence to study neutron transitions to the first and second excited state...

  17. Nuclear structure and double beta decay

    International Nuclear Information System (INIS)

    Vogel, P.

    1988-01-01

    Double beta decay is a rare transition between two nuclei of the same mass number A involving a change of the nuclear charge Z by two units. It has long been recognized that the Oν mode of double beta decay, where two electrons and no neutrinos are emitted, is a powerful tool for the study of neutrino properties. Its observation would constitute a convincing proof that there exists a massive Majorana neutrino which couples to electrons. Double beta decay is a process involving an intricate mixture of particle physics and physics of the nucleus. The principal nuclear physics issues have to do with the evaluation of the nuclear matrix elements responsible for the decay. If the authors wish to arrive at quantitative answers for the neutrino properties the authors have no choice but to learn first how to understand the nuclear mechanisms. The authors describe first the calculation of the decay rate of the 2ν mode of double beta decay, in which two electrons and two antineutrinos are emitted

  18. Labelling of. beta. -endorphin (. beta. -END) and. beta. -lipotropin (. beta. -LPH) by /sup 125/I

    Energy Technology Data Exchange (ETDEWEB)

    Deby-Dupont, G.; Joris, J.; Franchimont, P. (Universite de Liege (Belgique)); Reuter, A.M.; Vrindts-Gevaert, Y. (Institut des Radioelements, Fleurus (Belgique))

    1983-01-01

    5 ..mu..g of human ..beta..-endorphin were labelled with 2 mCi /sup 125/I by the chloramine T technique. After two gel filtrations on Sephadex G-15 and on Sephadex G-50 in phosphate buffer with EDTA, Trasylol and mercapto-ethanol, a pure tracer was obtained with a specific activity about 150 ..mu..Ci/..mu..g.Kept at + 4/sup 0/C, the tracer remained utilizable for 30 days without loss of immunoreactivity. The labelling with lactoperoxydase and the use of another gel filtration method (filtration on Aca 202) gave a /sup 125/I ..beta..-END tracer with the same immunoreactivity. The binding of this tracer to the antibody of an anti-..beta..-END antiserum diluted at 1/8000 was 32% with a non specific binding of 2%. 5 ..mu..g of human ..beta..-lipotropin were labelled with 0.5 mCi /sup 125/I by the lactoperoxydase method. After two gel filtrations on Sephadex G-25 and on Sephadex G-75 in phosphate buffer with EDTA, Trasylol and mercapto-ethanol, a pure tracer with a specific activity of 140 ..mu..Ci/..mu..g was obtained. It remained utilizable for 30 days when kept at + 4/sup 0/C. Gel filtration on Aca 202 did not give good purification, while gel filtration on Aca 54 was good but slower than on Sephadex G-75. The binding to antibody in absence of unlabelled ..beta..-LPH was 32% for an anti-..beta..-LPH antiserum diluted at 1/4000. The non specific binding was 2.5%.

  19. High-pressure behavior of beta-Ga2O3 nanocrystals

    DEFF Research Database (Denmark)

    Wang, H.; He, Y.; Chen, W.

    2010-01-01

    that nanocrystalline monoclinic beta-Ga2O3 underwent a phase transition to rhombohedral alpha-Ga2O3. It was found that beta- to alpha-Ga2O3 transition began at about 13.6-16.4 GPa, and extended up to 39.2 GPa. At the highest pressure used, only alpha-Ga2O3 was present, which remained after pressure release. A Birch......-Murnaghan fit to the P-V data yielded a zero-pressure bulk modulus at fixed B-0(')=4: B-0=228(9) GPa and B-0=333(19) GPa for beta-Ga2O3 and alpha-Ga2O3 phases, respectively. We compared our results with bulk beta-Ga2O3, and concluded that the phase-transition pressure and bulk modulus of nanocrystalline beta...

  20. Plasma beta HCG determination

    International Nuclear Information System (INIS)

    Amaral, L.B.D.; Pinto, J.C.M.; Linhares, E.; Linhares, Estevao

    1981-01-01

    There are three important indications for the early diagnosis of pregnancy through the determination of the beta sub-unit of chorionic gonadotrophin using radioimmunoassay: 1) some patient's or doctor's anxiety to discover the problem; 2) when it will be necessary to employ diagnostic or treatment procedures susceptible to affect the ovum; and 3) in the differential diagnosis of amenorrhoea, uterine hemorrhage and abdominal tumors. Other user's are the diagnosis of missed absortion, and the diagnosis and follow-up of chrorioncarcinoma. The AA. studied 200 determinations of plasma beta-HCG, considering the main difficulties occuring in the clinical use of this relevant laboratory tool in actual Obstetrics. (author) [pt

  1. Relation between the 2{nu}{beta}{beta} and 0{nu}{beta}{beta} nuclear matrix elements

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, Petr [Kellogg Radiation Laboratory, Caltech, Pasadena, CA 91125 (United States); Simkovic, Fedor [Department of Nuclear Physics and Biophysics, Comenius University, Mlynska dolina F1, SK-84248 Bratislava (Slovakia)

    2011-12-16

    A formal relation between the GT part of the nuclear matrix elements M{sub GT}{sup 0{nu}} of 0{nu}{beta}{beta} decay and the closure matrix elements M{sub cl}{sup 2{nu}} of 2{nu}{beta}{beta} decay is established. This relation is based on the integral representation of these quantities in terms of their dependence on the distance r between the two nucleons undergoing transformation. We also discuss the difficulties in determining the correct values of the closure 2{nu}{beta}{beta} decay matrix elements.

  2. {beta} {gamma} porch detector; Detecteur portique {beta} {gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Roulet, R [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1963-07-01

    This device is to be placed at the outside of reactors, hot laboratories and others where radioactive products are treated; it is intended to give the alarm when someone, passing through the porch is greatly contaminated, or carries, without his knowing, a radioactive substance. Being to be used in places where there might be an important ground noise, this device is provided with an automatic offset of this noise; an adjusting system of sensitivity allows to obtain a 15 {mu}Ci in {gamma} and 10 {mu}Ci in {beta} radioactive source, passing through the porch at the normal speed at which man is walking. A battery, set in buffer, allows working of the device, even when current is off. (author) [French] Cet appareil est destine a etre place a la sortie des reacteurs, laboratoires chauds ou autres laboratoires travaillant sur des produits radioactifs; son but est de donner une alarme lorsque quelqu'un, passant sous le portique, presente une forte contamination, ou surtout transporte par inadvertance un corps radioactif. Cet appareil devant etre utilise dans les lieux ou peut regner un bruit de fond important, possede une compensation automatique de ce bruit de fond; un reglage de la sensibilite permet d'obtenir au mieux un declenchement pour une source. de 15 {mu}Ci en {gamma} et 10 {mu}Ci en {beta} passant sous le portique a la vitesse normale d'un homme qui marche. Une batterie montee en tampon permet a l'appareil de fonctionner meme en cas de coupure de courant. (auteur)

  3. Gifts from Exoplanetary Transits

    Science.gov (United States)

    Narita, Norio

    2009-08-01

    The discovery of transiting extrasolar planets has enabled us to do a number of interesting studies. Transit photometry reveals the radius and the orbital inclination of transiting planets, which allows us to learn the true mass and density of the respective planets by the combined information from radial velocity (RV) measurements. In addition, follow-up observations of transiting planets, looking at such things as secondary eclipses, transit timing variations, transmission spectroscopy, and the Rossiter-McLaughlin effect, provide us information about their dayside temperatures, unseen bodies in systems, planetary atmospheres, and the obliquity of planetary orbits. Such observational information, which will provide us a greater understanding of extrasolar planets, is available only for transiting planets. Here, I briefly summarize what we can learn from transiting planets and introduce previous studies.

  4. Trichoderma .beta.-glucosidase

    Science.gov (United States)

    Dunn-Coleman, Nigel; Goedegebuur, Frits; Ward, Michael; Yao, Jian

    2006-01-03

    The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.

  5. Applied Beta Dosimetry

    International Nuclear Information System (INIS)

    Rich, B.L.

    1986-01-01

    Measurements of beta and/or nonpenetrating exposure results is complicated and past techniques and capabilities have resulted in significant inaccuracies in recorded results. Current developments have resulted in increased capabilities which make the results more accurate and should result in less total exposure to the work force. Continued development of works in progress should provide equivalent future improvements

  6. Beta thalassemia - a review

    Directory of Open Access Journals (Sweden)

    R Jha

    2014-09-01

    Full Text Available Thalassemia is a globin gene disorder that results in a diminished rate of synthesis of one or more of the globin chains. About 1.5% of the global population (80 to 90 million people are carriers of beta Thalassemia. More than 200 mutations are described in beta thalassemia. However not all mutations are common in different ethnic groups. The only effective way to reduce burden of thalassemia is to prevent birth of homozygotes. Diagnosis of beta thalassemia can be done by fetal DNA analysis for molecular defects of beta thalassemia or by fetal blood analysis. Hematopoietic stem cell transplantation is the only available curative approach for Thalassemia. Many patients with thalassemia in underdeveloped nations die in childhood or adolescence. Programs that provide acceptable care, including transfusion of safe blood and supportive therapy including chelation must be established.DOI: http://dx.doi.org/10.3126/jpn.v4i8.11609 Journal of Pathology of Nepal; Vol.4,No. 8 (2014 663-671

  7. Double Beta Decay Experiments

    International Nuclear Information System (INIS)

    Piepke, A.

    2005-01-01

    The experimental observation of neutrino oscillations and thus neutrino mass and mixing gives a first hint at new particle physics. The absolute values of the neutrino mass and the properties of neutrinos under CP-conjugation remain unknown. The experimental investigation of the nuclear double beta decay is one of the key techniques for solving these open problems

  8. The pleiotropic roles of transforming growth factor beta inhomeostasis and carcinogenesis of endocrine organs.

    Energy Technology Data Exchange (ETDEWEB)

    Fleisch, Markus C.; Maxwell, Christopher A.; Barcellos-Hoff,Mary-Helen

    2006-01-13

    Transforming growth factor beta (TGF-beta) is a ubiquitous cytokine that plays a critical role in numerous pathways regulating cellular and tissue homeostasis. TGF-beta is regulated by hormones and is a primary mediator of hormone response in uterus, prostate and mammary gland. This review will address the role of TGF-beta in regulating hormone dependent proliferation and morphogenesis. The subversion of TGF-beta regulation during the processes of carcinogenesis, with particular emphasis on its effects on genetic stability and epithelial to mesenchymal transition (EMT), will also be examined. An understanding of the multiple and complex mechanisms of TGF-beta regulation of epithelial function, and the ultimate loss of TGF-beta function during carcinogenesis, will be critical in the design of novel therapeutic interventions for endocrine-related cancers.

  9. Beta cell adaptation in pregnancy

    DEFF Research Database (Denmark)

    Nielsen, Jens Høiriis

    2016-01-01

    Pregnancy is associated with a compensatory increase in beta cell mass. It is well established that somatolactogenic hormones contribute to the expansion both indirectly by their insulin antagonistic effects and directly by their mitogenic effects on the beta cells via receptors for prolactin...... and growth hormone expressed in rodent beta cells. However, the beta cell expansion in human pregnancy seems to occur by neogenesis of beta cells from putative progenitor cells rather than by proliferation of existing beta cells. Claes Hellerström has pioneered the research on beta cell growth for decades...... in the expansion of the beta cell mass in human pregnancy, and the relative roles of endocrine factors and nutrients....

  10. Interactions between an alpha-helix and a beta-sheet. Energetics of alpha/beta packing in proteins.

    Science.gov (United States)

    Chou, K C; Némethy, G; Rumsey, S; Tuttle, R W; Scheraga, H A

    1985-12-05

    Conformational energy computations have been carried out to determine the favorable ways of packing a right-handed alpha-helix on a right-twisted antiparallel or parallel beta-sheet. Co-ordinate transformations have been developed to relate the position and orientation of the alpha-helix to the beta-sheet. The packing was investigated for a CH3CO-(L-Ala)16-NHCH3 alpha-helix interacting with five-stranded beta-sheets composed of CH3CO-(L-Val)6-NHCH3 chains. All internal and external variables for both the alpha-helix and the beta-sheet were allowed to change during energy minimization. Four distinct classes of low-energy packing arrangements were found for the alpha-helix interacting with both the parallel and the anti-parallel beta-sheet. The classes differ in the orientation of the axis of the alpha-helix relative to the direction of the strands of the right-twisted beta-sheet. In the class with the most favorable arrangement, the alpha-helix is oriented along the strands of the beta-sheet, as a result of attractive non-bonded side-chain-side-chain interactions along the entire length of the alpha-helix. A class with nearly perpendicular orientation of the helix axis to the strands is also of low energy, because it allows similarly extensive attractive interactions. In the other two classes, the helix is oriented diagonally relative to the strands of the beta-sheet. In one of them, it interacts with the convex surface near the middle of the saddle-shaped twisted beta-sheet. In the other, it is oriented along the concave diagonal of the beta-sheet and, therefore, it interacts only with the corner regions of the sheet, so that this packing is energetically less favorable. The packing arrangements involving an antiparallel and a parallel beta-sheet are generally similar, although the antiparallel beta-sheet has been found to be more flexible. The major features of 163 observed alpha/beta packing arrangements in 37 proteins are accounted for in terms of the computed

  11. Misleading Betas: An Educational Example

    Science.gov (United States)

    Chong, James; Halcoussis, Dennis; Phillips, G. Michael

    2012-01-01

    The dual-beta model is a generalization of the CAPM model. In the dual-beta model, separate beta estimates are provided for up-market and down-market days. This paper uses the historical "Anscombe quartet" results which illustrated how very different datasets can produce the same regression coefficients to motivate a discussion of the…

  12. Interaction with beta-arrestin determines the difference in internalization behavor between beta1- and beta2-adrenergic receptors.

    Science.gov (United States)

    Shiina, T; Kawasaki, A; Nagao, T; Kurose, H

    2000-09-15

    The beta(1)-adrenergic receptor (beta(1)AR) shows the resistance to agonist-induced internalization. As beta-arrestin is important for internalization, we examine the interaction of beta-arrestin with beta(1)AR with three different methods: intracellular trafficking of beta-arrestin, binding of in vitro translated beta-arrestin to intracellular domains of beta(1)- and beta(2)ARs, and inhibition of betaAR-stimulated adenylyl cyclase activities by beta-arrestin. The green fluorescent protein-tagged beta-arrestin 2 translocates to and stays at the plasma membrane by beta(2)AR stimulation. Although green fluorescent protein-tagged beta-arrestin 2 also translocates to the plasma membrane, it returns to the cytoplasm 10-30 min after beta(1)AR stimulation. The binding of in vitro translated beta-arrestin 1 and beta-arrestin 2 to the third intracellular loop and the carboxyl tail of beta(1)AR is lower than that of beta(2)AR. The fusion protein of beta-arrestin 1 with glutathione S-transferase inhibits the beta(1)- and beta(2)AR-stimulated adenylyl cyclase activities, although inhibition of the beta(1)AR-stimulated activity requires a higher concentration of the fusion protein than that of the beta(2)AR-stimulated activity. These results suggest that weak interaction of beta(1)AR with beta-arrestins explains the resistance to agonist-induced internalization. This is further supported by the finding that beta-arrestin can induce internalization of beta(1)AR when beta-arrestin 1 does not dissociate from beta(1)AR by fusing to the carboxyl tail of beta(1)AR.

  13. Production and study of high-beta plasma confined by a superconducting dipole magnet

    International Nuclear Information System (INIS)

    Garnier, D.T.; Hansen, A.; Mauel, M.E.; Ortiz, E.; Boxer, A.C.; Ellsworth, J.; Karim, I.; Kesner, J.; Mahar, S.; Roach, A.

    2006-01-01

    The Levitated Dipole Experiment (LDX) [J. Kesner et al., in Fusion Energy 1998, 1165 (1999)] is a new research facility that is exploring the confinement and stability of plasma created within the dipole field produced by a strong superconducting magnet. Unlike other configurations in which stability depends on curvature and magnetic shear, magnetohydrodynamic stability of a dipole derives from plasma compressibility. Theoretically, the dipole magnetic geometry can stabilize a centrally peaked plasma pressure that exceeds the local magnetic pressure (β>1), and the absence of magnetic shear allows particle and energy confinement to decouple. In initial experiments, long-pulse, quasi-steady-state microwave discharges lasting more than 10 s have been produced that are consistent with equilibria having peak beta values of 20%. Detailed measurements have been made of discharge evolution, plasma dynamics and instability, and the roles of gas fueling, microwave power deposition profiles, and plasma boundary shape. In these initial experiments, the high-field superconducting floating coil was supported by three thin supports. The plasma is created by multifrequency electron cyclotron resonance heating at 2.45 and 6.4 GHz, and a population of energetic electrons, with mean energies above 50 keV, dominates the plasma pressure. Creation of high-pressure, high-beta plasma is possible only when intense hot electron interchange instabilities are stabilized by sufficiently high background plasma density. A dramatic transition from a low-density, low-beta regime to a more quiescent, high-beta regime is observed when the plasma fueling rate and confinement time become sufficiently large

  14. Magnitude of a conformational change in the glycine receptor beta1-beta2 loop is correlated with agonist efficacy

    DEFF Research Database (Denmark)

    Pless, Stephan Alexander; Lynch, Joseph W

    2009-01-01

    associated with the closed-flip transition in the alpha1-glycine receptor. We employed voltage-clamp fluorometry to compare ligand-binding domain conformational changes induced by the following agonists, listed from highest to lowest affinity and efficacy: glycine > beta-alanine > taurine. Voltage...

  15. Exchange effects in double beta decay

    International Nuclear Information System (INIS)

    Stephenson, G.J. Jr.; Goldman, T.; Maltman, K.R.; Schmidt, K.E.

    1988-01-01

    The motivation underlying the resurgence of interest in double beta decay is the hope that the observation of or limits on the 0-neutrino mode will provide information about the nature of the neutrino. This clearly requires confidence in the nuclear matrix elements involved in the transition. The shell model calculations do not agree well with the geochemical values for 130 Te, which has lead to a spate of papers offering specific fixes for the problem. In this contribution we shall not comment on any of the specific nuclear calculations, rather we make some remarks which should be relevant to any model calculation

  16. Low-beta investment strategies

    OpenAIRE

    Korn, Olaf; Kuntz, Laura-Chloé

    2015-01-01

    This paper investigates investment strategies that exploit the low-beta anomaly. Although the notion of buying low-beta stocks and selling high-beta stocks is natural, a choice is necessary with respect to the relative weighting of high-beta stocks and low-beta stocks in the investment portfolio. Our empirical results for US large-cap stocks show that this choice is very important for the risk-return characteristics of the resulting portfolios and their sensitivities to common risk factors. W...

  17. Neutrophil beta-2 microglobulin: an inflammatory mediator

    DEFF Research Database (Denmark)

    Bjerrum, O W; Nissen, Mogens Holst; Borregaard, N

    1990-01-01

    Beta-2 microglobulin (beta 2m) constitutes the light invariant chain of HLA class I antigen, and is a constituent of mobilizable compartments of neutrophils. Two forms of beta 2m exist: native beta 2m and proteolytically modified beta 2m (Des-Lys58-beta 2m), which shows alpha mobility in crossed ...

  18. Beta decay of neutron-rich transuranic nuclei

    International Nuclear Information System (INIS)

    Hoff, R.W.

    1986-01-01

    Allowance is made for beta-delayed fission in the calculation of the mass yield of underground thermonuclear explosions. This allowance is made by calculating a correction factor by four different methods. These correction factors are applied to a simple model of product yield and the accuracy and potential usefulness of the results are discussed. 19 refs., 3 figs., 1 tab

  19. Beta-thalassemia

    Directory of Open Access Journals (Sweden)

    Origa Raffaella

    2010-05-01

    Full Text Available Abstract Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic individuals. The total annual incidence of symptomatic individuals is estimated at 1 in 100,000 throughout the world and 1 in 10,000 people in the European Union. Three main forms have been described: thalassemia major, thalassemia intermedia and thalassemia minor. Individuals with thalassemia major usually present within the first two years of life with severe anemia, requiring regular red blood cell (RBC transfusions. Findings in untreated or poorly transfused individuals with thalassemia major, as seen in some developing countries, are growth retardation, pallor, jaundice, poor musculature, hepatosplenomegaly, leg ulcers, development of masses from extramedullary hematopoiesis, and skeletal changes that result from expansion of the bone marrow. Regular transfusion therapy leads to iron overload-related complications including endocrine complication (growth retardation, failure of sexual maturation, diabetes mellitus, and insufficiency of the parathyroid, thyroid, pituitary, and less commonly, adrenal glands, dilated myocardiopathy, liver fibrosis and cirrhosis. Patients with thalassemia intermedia present later in life with moderate anemia and do not require regular transfusions. Main clinical features in these patients are hypertrophy of erythroid marrow with medullary and extramedullary hematopoiesis and its complications (osteoporosis, masses of erythropoietic tissue that primarily affect the spleen, liver, lymph nodes, chest and spine, and bone deformities and typical facial changes, gallstones, painful leg ulcers and increased predisposition to thrombosis. Thalassemia minor is clinically asymptomatic but some subjects may have moderate anemia. Beta-thalassemias are caused by point mutations or, more rarely

  20. Beta and Gamma Gradients

    DEFF Research Database (Denmark)

    Løvborg, Leif; Gaffney, C. F.; Clark, P. A.

    1985-01-01

    Experimental and/or theoretical estimates are presented concerning, (i) attenuation within the sample of beta and gamma radiation from the soil, (ii) the gamma dose within the sample due to its own radioactivity, and (iii) the soil gamma dose in the proximity of boundaries between regions...... of differing radioactivity. It is confirmed that removal of the outer 2 mm of sample is adequate to remove influence from soil beta dose and estimates are made of the error introduced by non-removal. Other evaluations include variation of the soil gamma dose near the ground surface and it appears...... that the present practice of avoiding samples above a depth of 0.3 m may be over-cautious...

  1. Regulation of beta cell replication

    DEFF Research Database (Denmark)

    Lee, Ying C; Nielsen, Jens Høiriis

    2008-01-01

    Beta cell mass, at any given time, is governed by cell differentiation, neogenesis, increased or decreased cell size (cell hypertrophy or atrophy), cell death (apoptosis), and beta cell proliferation. Nutrients, hormones and growth factors coupled with their signalling intermediates have been...... suggested to play a role in beta cell mass regulation. In addition, genetic mouse model studies have indicated that cyclins and cyclin-dependent kinases that determine cell cycle progression are involved in beta cell replication, and more recently, menin in association with cyclin-dependent kinase...... inhibitors has been demonstrated to be important in beta cell growth. In this review, we consider and highlight some aspects of cell cycle regulation in relation to beta cell replication. The role of cell cycle regulation in beta cell replication is mostly from studies in rodent models, but whether...

  2. High beta experiments in CHS

    International Nuclear Information System (INIS)

    Okamura, S.; Matsuoka, K.; Nishimura, K.

    1994-09-01

    High beta experiments were performed in the low-aspect-ratio helical device CHS with the volume-averaged equilibrium beta up to 2.1 %. These values (highest for helical systems) are obtained for high density plasmas in low magnetic field heated with two tangential neutral beams. Confinement improvement given by means of turning off gas puffing helped significantly to make high betas. Magnetic fluctuations increased with increasing beta, but finally stopped to increase in the beta range > 1 %. The coherent modes appearing in the magnetic hill region showed strong dependence on the beta values. The dynamic poloidal field control was applied to suppress the outward plasma movement with the plasma pressure. Such an operation gave fixed boundary operations of high beta plasmas in helical systems. (author)

  3. Characterization of a Commercial Silicon Beta Cell

    International Nuclear Information System (INIS)

    Foxe, Michael P.; Hayes, James C.; Mayer, Michael F.; McIntyre, Justin I.; Sivels, Ciara B.; Suarez, Rey

    2016-01-01

    Silicon detectors are of interest for the verification of the Comprehensive Nuclear-Test-Ban Treaty (CTBT) due to their enhanced energy resolution compared to plastic scintillators beta cells. Previous work developing a figure-of-merit (FOM) for comparison of beta cells suggests that the minimum detectable activity (MDA) could be reduced by a factor of two to three with the use of silicon detectors. Silicon beta cells have been developed by CEA (France) and Lares Ltd. (Russia), with the PIPSBox developed by CEA being commercially available from Canberra for approximately $35k, but there is still uncertainty about the reproducibility of the capabilities in the field. PNNL is developing a high-resolution beta-gamma detector system in the shallow underground laboratory, which will utilize and characterize the operation of the PIPSBox detector. Throughout this report, we examine the capabilities of the PIPSBox as developed by CEA. The lessons learned through the testing and use of the PIPSBox will allow PNNL to strategically develop a silicon detector optimized to better suit the communities needs in the future.

  4. Beta decay of highly charged ions

    International Nuclear Information System (INIS)

    Litvinov, Yuri A; Bosch, Fritz

    2011-01-01

    Beta decay of highly charged ions has attracted much attention in recent years. An obvious motivation for this research is that stellar nucleosynthesis proceeds at high temperatures where the involved atoms are highly ionized. Another important reason is addressing decays of well-defined quantum-mechanical systems, such as one-electron ions where all interactions with other electrons are excluded. The largest modifications of nuclear half-lives with respect to neutral atoms have been observed in beta decay of highly charged ions. These studies can be performed solely at ion storage rings and ion traps, because there high atomic charge states can be preserved for extended periods of time (up to several hours). Currently, all experimental results available in this field originate from experiments at the heavy-ion complex GSI in Darmstadt. There, the fragment separator facility FRS allows the production and separation of exotic, highly charged nuclides, which can then be stored and investigated in the storage ring facility ESR. In this review, we present and discuss in particular two-body beta decays, namely bound-state beta decay and orbital electron capture. Although we focus on experiments conducted at GSI, we will also attempt to provide general requirements common to any other experiment in this context. Finally, we address challenging but not yet performed experiments and we give prospects for the new radioactive beam facilities, such as FAIR in Darmstadt, IMP in Lanzhou and RIKEN in Wako.

  5. Beta rays and neutrinos

    International Nuclear Information System (INIS)

    Adams, S.F.

    1992-01-01

    It was over 30 years between the first observation of the enigmatic process of beta decay and the first postulation of the neutrino. It took a further 26 years until the first neutrino was detected and yet another 27 until the electroweak theory was confirmed by the discovery of W and Z particles. This article traces some of the puzzles and paradoxes associated with the history of the neutrino. (author)

  6. Coroutine Sequencing in BETA

    DEFF Research Database (Denmark)

    Kristensen, Bent Bruun; Madsen, Ole Lehrmann; Møller-Pedersen, Birger

    In object-oriented programming, a program execution is viewed as a physical model of some real or imaginary part of the world. A language supporting object-oriented programming must therefore contain comprehensive facilities for modeling phenomena and concepts form the application domain. Many...... applications in the real world consist of objects carrying out sequential processes. Coroutines may be used for modeling objects that alternate between a number of sequential processes. The authors describe coroutines in BETA...

  7. COM Support in BETA

    DEFF Research Database (Denmark)

    Madsen, Ole Lehrmann

    1999-01-01

    Component technologies based on binary units of independent production are some of the most important contributions to software architecture and reuse during recent years. Especially the COM technologies and the CORBA standard from the Object Management Group have contributed new and interesting...... principles for software architecture, and proven to be useful in parctice. In this paper ongoing work with component support in the BETA language is described....

  8. LHCb: $2\\beta_s$ measurement at LHCb

    CERN Multimedia

    Conti, G

    2009-01-01

    A measurement of $2\\beta_s$, the phase of the $B_s-\\bar{B_s}$ oscillation amplitude with respect to that of the ${\\rm b} \\rightarrow {\\rm c^{+}}{\\rm W^{-}}$ tree decay amplitude, is one of the key goals of the LHCb experiment with first data. In the Standard Model (SM), $2\\beta_s$ is predicted to be $0.0360^{+0.0020}_{-0.0016} \\rm rad$. The current constraints from the Tevatron are: $2\\beta_{s}\\in[0.32 ; 2.82]$ at 68$\\%$CL from the CDF experiment and $2\\beta_{s}=0.57^{+0.24}_{-0.30}$ from the D$\\oslash$ experiment. Although the statistical uncertainties are large, these results hint at the possible contribution of New Physics in the $B_s-\\bar{B_s}$ box diagram. After one year of data taking at LHCb at an average luminosity of $\\mathcal{L}\\sim2\\cdot10^{32}\\rm cm^{-2} \\rm s^{-1}$ (integrated luminosity $\\mathcal{L}_{\\rm int}\\sim 2 \\rm fb^{-1}$), the expected statistical uncertainty on the measurement is $\\sigma(2\\beta_s)\\simeq 0.03$. This uncertainty is similar to the $2\\beta_s$ value predicted by the SM.

  9. [{sup 18}F]{beta}-CIT-FP is superior to [{sup 11}C]{beta}-CIT-FP for quantitation of the dopamine transporter

    Energy Technology Data Exchange (ETDEWEB)

    Lundkvist, Camilla; Halldin, Christer; Ginovart, Nathalie; Swahn, Carl-Gunnar; Farde, Lars

    1997-10-01

    {beta}-CIT-FP [N-(3-fluoropropyl)-2{beta}-carbomethoxy-3{beta}-(4-iodophenyl)nortropane] is a cocaine analogue with high affinity for the dopamine transporter. Positron emission tomography (PET) studies with [O-methyl-{sup 11}C]{beta}-CIT-FP ([{sup 11}C]{beta}-CIT-FP) has shown that equilibrium conditions were approached but, however, not reached at the end of measurement. Moreover, metabolite studies of [{sup 11}C]{beta}-CIT-FP in monkey plasma demonstrated a lipophilic-labelled metabolite that may enter the brain. We therefore labelled {beta}-CIT-FP with fluorine-18 in a position that may avoid the formation of labelled lipophilic metabolites. The more long-lived radionuclide ({sup 18}F) was used to allow for measurements over longer time. [N-fluoropropyl-{sup 18}F]{beta}-CIT-FP ([{sup 18}F]{beta}-CIT-FP) was prepared by N-alkylation of nor-{beta}-CIT with [{sup 18}F]fluoropropyl bromide. PET studies were performed in cynomolgus monkeys. [{sup 18}F]{beta}-CIT-FP entered the brain rapidly. There was a high concentration of radioactivity in the striatum and much lower in the thalamus, neocortex, and cerebellum. The striatum-to-cerebellum ratio was about 5 at time of transient equilibrium, which occurred after 60 to 100 min. After pretreatment with GBR 12909, radioactivity in the striatum was markedly reduced, thus indicating specific [{sup 18}F]{beta}-CIT-FP binding to the dopamine transporter. The fraction of unchanged [{sup 18}F]{beta}-CIT-FP determined by HPLC was 10-15% after 140 min. No lipophilic labelled metabolites were detected. The absence of measurable lipophilic labelled metabolites and the occurrence of transient equilibrium within the time of the PET measurement indicate that [{sup 18}F]{beta}-CIT-FP is superior to [{sup 11}C]{beta}-CIT-FP as a PET radioligand for quantification of the dopamine transporter in the human brain.

  10. Transitional Justice

    DEFF Research Database (Denmark)

    Gissel, Line Engbo

    This presentation builds on an earlier published article, 'Contemporary Transitional Justice: Normalising a Politics of Exception'. It argues that the field of transitional justice has undergone a shift in conceptualisation and hence practice. Transitional justice is presently understood to be th...... to be the provision of ordinary criminal justice in contexts of exceptional political transition.......This presentation builds on an earlier published article, 'Contemporary Transitional Justice: Normalising a Politics of Exception'. It argues that the field of transitional justice has undergone a shift in conceptualisation and hence practice. Transitional justice is presently understood...

  11. Enantioselective synthesis of alpha,beta-disubstituted-beta-amino acids.

    Science.gov (United States)

    Sibi, Mukund P; Prabagaran, Narayanasamy; Ghorpade, Sandeep G; Jasperse, Craig P

    2003-10-01

    Highly diastereoselective and enantioselective addition of N-benzylhydroxylamine to imides 17 and 20-30 produces alpha,beta-trans-disubstituted N-benzylisoxazolidinones 19 and 31-41. These reactions proceed in 60-96% ee with 93-99% de's using 5 mol % of Mg(NTf2)2 and ligand 18. The product isoxazolidinones can be hydrogenolyzed directly to provide alpha,beta-disubstituted-beta-amino acids.

  12. Relativistic pn-QRPA to the double beta decay

    International Nuclear Information System (INIS)

    Conti, Claudio de; Krmpotic, F.; Carlson, Brett Vern

    2010-01-01

    Full text: In nature there are about 50 nuclear systems where the single beta-decay is energetically forbidden, and double- beta decay turns out to be only possible mode of disintegration. It is the nuclear pairing force which causes such an 'anomaly', by making the mass of the odd-odd isobar, (N - 1;Z + 1), to be greater than the masses of its even-even neighbors, (N;Z) and (N - 2;Z +2). The modes by which the double-beta decay can take place are connected with the neutrino and antineutrino distinction. In case the lepton number is strictly conserved the neutrino is a Dirac fermion and the two-neutrino mode is the only possible mode of disintegration. On the other hand, if this conservation is violated, the neutrino is a Majorana particle and neutrinoless double-beta decay also can occur. Both two-neutrino and neutrinoless double-beta decay processes have attracted much attention, because a comparison between experiment and theory for the first, provides a measure of confidence one may have in the nuclear wave function employed for extracting the unknown parameters from neutrinoless lifetime measurements. The proton-neutron (pn) quasiparticle random phase approximation (QRPA) has turned out be the most simple model for calculating the nuclear wave function involved in the double-beta decay transitions. In this work the transition matrix elements for 0 + -> 0 + double-beta decay are calculated for 48 Ca, 76 Ge, 82 Se, 100 Mo, 128 Te and 130 Te nuclei, using a relativistic pn-QRPA based on Hartree-Bogoliubov approximation to the single-particle motion. (author)

  13. Relativistic pn-QRPA to the double beta decay

    International Nuclear Information System (INIS)

    Conti, Claudio de; Krmpotic, Francisco; Carlson, Brett Vern

    2011-01-01

    Full text: In nature there are about 50 nuclear systems where the single beta-decay is energetically forbidden, and double-beta decay turns out to be only possible mode of disintegration. It is the nuclear pairing force which causes such an 'anomaly', by making the mass of the odd-odd isobar, (N - 1;Z + 1), to be greater than the masses of its even-even neighbors, (N;Z) and (N - 2;Z +2). The modes by which the double-beta decay can take place are connected with the neutrino and antineutrino distinction. In case the lepton number is strictly conserved the neutrino is a Dirac fermion and the two-neutrino mode is the only possible mode of disintegration. On the other hand, if this conservation is violated, the neutrino is a Majorana particle and neutrinoless double-beta decay also can occur. Both two-neutrino and neutrinoless double-beta decay processes have attracted much attention, because a comparison between experiment and theory for the first, provides a measure of confidence one may have in the nuclear wave function employed for extracting the unknown parameters from neutrinoless lifetime measurements. The proton-neutron (pn) quasiparticle random phase approximation (QRPA) has turned out be the most simple model for calculating the nuclear wave function involved in the double-beta decay transitions. In this work the transition matrix elements for 0 + → 0 + double-beta decay are calculated for 48 Ca, 76 Ge, 82 Se, 100 Mo, 128 Te and 130 Te nuclei, using a relativistic pn-QRPA based on Hartree-Bogoliubov approximation to the single-particle motion. (author)

  14. 46 CFR 154.440 - Allowable stress.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Allowable stress. 154.440 Section 154.440 Shipping COAST... Tank Type A § 154.440 Allowable stress. (a) The allowable stresses for an independent tank type A must... Commandant (CG-522). (b) A greater allowable stress than required in paragraph (a)(1) of this section may be...

  15. 46 CFR 154.421 - Allowable stress.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Allowable stress. 154.421 Section 154.421 Shipping COAST... § 154.421 Allowable stress. The allowable stress for the integral tank structure must meet the American Bureau of Shipping's allowable stress for the vessel's hull published in “Rules for Building and Classing...

  16. 34 CFR 304.21 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Allowable costs. 304.21 Section 304.21 Education... Grantee § 304.21 Allowable costs. In addition to the allowable costs established in the Education... allowable expenditures by projects funded under the program: (a) Cost of attendance, as defined in Title IV...

  17. 2 CFR 215.27 - Allowable costs.

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Allowable costs. 215.27 Section 215.27... § 215.27 Allowable costs. For each kind of recipient, there is a set of Federal principles for determining allowable costs. Allowability of costs shall be determined in accordance with the cost principles...

  18. 50 CFR 80.15 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Allowable costs. 80.15 Section 80.15... WILDLIFE RESTORATION AND DINGELL-JOHNSON SPORT FISH RESTORATION ACTS § 80.15 Allowable costs. (a) What are allowable costs? Allowable costs are costs that are necessary and reasonable for accomplishment of approved...

  19. 49 CFR 266.11 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Allowable costs. 266.11 Section 266.11... TRANSPORTATION ACT § 266.11 Allowable costs. Allowable costs include only the following costs which are properly allocable to the work performed: Planning and program operation costs which are allowed under Federal...

  20. Beta measurement evaluation and upgrade

    International Nuclear Information System (INIS)

    Swinth, K.L.; Rathbun, L.A.; Roberson, P.L.; Endres, G.W.R.

    1986-01-01

    This program focuses on the resolution of problems associated with the field measurement of the beta dose component at Department of Energy (DOE) facilities. The change in DOE programs, including increased efforts in improved waste management and decontamination and decommissioning (D and D) of facilities, coupled with beta measurement problems identified at Three Mile Island has increased the need to improve beta measurements. In FY 1982, work was initiated to provide a continuing effort to identify problems associated with beta dose assessment at DOE facilities. The problems identified resulted in the development of this program. The investigation includes (1) an assessment of measurement systems now in use, (2) development of improved calibration systems and procedures, (3) application of innovative beta dosimetry concepts, (4) investigation of new instruments or concepts for monitoring and spectroscopy, and (5) development of recommendations to assure an adequate beta measurement program within DOE facilities

  1. Beta Neutrino Correlation Measurement with Trapped Radioactive Ions

    International Nuclear Information System (INIS)

    Velten, Ph.; Ban, G.; Durand, D.; Flechard, X.; Lienard, E.; Mauger, F.; Naviliat-Cuncic, O.; Mery, A.; Rodriguez, D.; Thomas, J.-C.

    2010-01-01

    The beta-neutrino angular correlation coefficient provides a sensitive observable to search for physics beyond the standard electroweak model in nuclear beta decay. We address here the measurement of this parameter in the pure Gamow-Teller transition of 6 He. A deviation from the standard model prediction would indicate the existence of tensor like couplings, possibly mediated by new bosons like leptoquarks. The aim of the LPCTrap experiment is to measure this coefficient with a statistical uncertainty of 0.5% using a novel transparent Paul trap. The status of the experiment is briefly presented along with the work in progress.

  2. Structural analyses of polymorphic transitions of sn-1, 3-distearoyl-2-oleoylglycerol (SOS) and sn-1, 3-dioleoyl-2-stearoylglycerol (OSO): assessment on steric hindrance of unsaturated and saturated acyl chain interactions.

    Science.gov (United States)

    Yano, J; Sato, K; Kaneko, F; Small, D M; Kodali, D R

    1999-01-01

    Polymorphic transformations in two saturated-unsaturated mixed acid triacylglycerols, SOS (sn -1,3-distearoyl-2-oleoylglycerol) and OSO (sn -1,3-dioleoyl-2-stearoylglycerol), have been studied by FT-IR spectroscopy using deuterated specimens in which stearoyl chains are fully deuterated. A reversible phase transition between sub alpha and alpha and a series of irreversible transitions (alpha-->gamma-->beta'-->beta (beta2, beta1) for SOS and alpha-->beta'-->beta for OSO) were studied with an emphasis on the conformational ordering process of stearoyl and oleoyl chains. The alpha-->sub alpha reversible transition was due to the orientational change of stearoyl chains in the lateral directions from the hexagonal subcell to a perpendicularly packed one. As the first stage of the series of irreversible transitions from alpha to beta, the conformational ordering of saturated chains took place in the alpha-->gamma transition of SOS and in the alpha-->beta' transition of OSO; one stearoyl chain in SOS and OSO takes the all-trans conformation and the second stearoyl chain in SOS takes the bent conformation like those observed in the most stable beta-type. As the final stage, the ordering of unsaturated chains occurred in the beta'-->beta transition both for SOS and OSO. A conversion in the layered structure from bilayer to trilayer was also accompanied by the conformational ordering in the alpha-->gamma transition of SOS and in the beta'-->beta transition of OSO.

  3. Conditional Betas and Investor Uncertainty

    OpenAIRE

    Fernando D. Chague

    2013-01-01

    We derive theoretical expressions for market betas from a rational expectation equilibrium model where the representative investor does not observe if the economy is in a recession or an expansion. Market betas in this economy are time-varying and related to investor uncertainty about the state of the economy. The dynamics of betas will also vary across assets according to the assets' cash-flow structure. In a calibration exercise, we show that value and growth firms have cash-flow structures...

  4. Study of {sup 193}Os beta{sup -} decay; Estudo do decaimento beta{sup -} do {sup 193}Os

    Energy Technology Data Exchange (ETDEWEB)

    Zahn, Guilherme Soares

    2006-07-01

    In this work, the excited levels of {sup 193}Ir populated by the beta{sup -} decay of {sup 193}Os (T{sub 1/2} {approx} 30h) were investigated. For that purpose, {approx} 5 mg samples of 99%-enriched {sup 192}Os were irradiated under a thermal neutron flux of {approx} 10{sup 12} s{sup -1} and then analysed both using single gamma spectroscopy and a 4-detector multi parametric acquisition facility, which provided data for both a gamma gamma coincidence analysis and a directional angular correlation gamma gamma ({theta} ) study. From these data, 28 transitions were added to this decay scheme, 11 of which were previously known from nuclear reactions and 17 observed for the first time. Eight excited levels were also added to the decay scheme, 3 of which were known from nuclear reaction studies - the remaining 5 are suggested for the first time. Moreover, it was possible to confirm suspicions found in reference that the levels at 848.93 keV and 849.093 keV are indeed the same; it was also possible to confirm the existence of an excited level at 806.9 keV, which had been inferred, but not experimentally confirmed in beta decay studies to date. The angular correlation analysis allowed for the definition of the spin of the excited level at 874 keV as 5/2{sup +;} moreover, the results showed a 79% probability that the spin of the 1078 keV level is 5/2/'-, and also restricted the spin possibilities for the new excited level at 960 keV to two values (1/2 or 3/2). It was also possible to measure the multipolarity mixing ratio ({delta}{sub Ln+1}/L{sub n}) for 43 transitions - 19 of them for the first time and most of the others with a better precision than previously known. Finally, an attempt was made to understand the low-lying levels structure for this nucleus using a theoretical model, which reproduced the ground state and the two lowest-lying excited levels in {sup 193}Ir. (author)

  5. Dynamic returns of beta arbitrage

    OpenAIRE

    Nascimento, Mafalda

    2017-01-01

    This thesis studies the patterns of the abnormal returns of the beta strategy. The topic can be helpful for professional investors, who intend to achieve a better performance in their portfolios. Following the methodology of Lou, Polk, & Huang (2016), the COBAR measure is computed in order to determine the levels of beta arbitrage in the market in each point in time. It is argued that beta arbitrage activity can have impact on the returns of the beta strategy. In fact, it is demonstrated that...

  6. Integration of BETA with Eclipse

    DEFF Research Database (Denmark)

    Andersen, Peter; Madsen, Ole Lehrmann; Enevoldsen, Mads Brøgger

    2004-01-01

    This paper presents language interoperability issues appearing in order to implement support for the BETA language in the Java-based Eclipse integrated development environment. One of the challenges is to implement plug-ins in BETA and be able to load them in Eclipse. In order to do this, some fo...... it is possible to implement plug-ins in BETA and even inherit from Java classes. In the paper the two approaches are described together with part of the mapping from BETA to Java class files. http://www.sciencedirect.com/science/journal/15710661...

  7. Simultaneous beta and gamma spectroscopy

    Science.gov (United States)

    Farsoni, Abdollah T.; Hamby, David M.

    2010-03-23

    A phoswich radiation detector for simultaneous spectroscopy of beta rays and gamma rays includes three scintillators with different decay time characteristics. Two of the three scintillators are used for beta detection and the third scintillator is used for gamma detection. A pulse induced by an interaction of radiation with the detector is digitally analyzed to classify the type of event as beta, gamma, or unknown. A pulse is classified as a beta event if the pulse originated from just the first scintillator alone or from just the first and the second scintillator. A pulse from just the third scintillator is recorded as gamma event. Other pulses are rejected as unknown events.

  8. A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions

    International Nuclear Information System (INIS)

    Cupples, C.G.; Miller, J.H.

    1989-01-01

    We describe the construction of six strains of Escherichia coli with different mutations at the same coding position in the lacZ gene, which specifies the active site glutamic acid residue at position 461 in beta'-galactosidase. Each strain is Lac- and reverts to Lac+ only by restoring the glutamic acid codon. The strains have been designed so that each reverts via one of the six base substitutions. The set of strains allows detection of each transition and transversion simply by monitoring the Lac- to Lac+ frequency, as demonstrated here with characterized mutagens and mutator alleles. These strains are useful for rapidly determining the mutagenic specificity of mutagens at a single site, for detecting low levels of stimulation of certain base substitutions, for monitoring specific base changes in response to various experimental conditions or strain backgrounds, and for isolating new mutator strains

  9. Beta-decay study of T{sub z}=-2 proton-rich nucleus {sup 24}Si

    Energy Technology Data Exchange (ETDEWEB)

    Ichikawa, Y.; Iwasaki, H.; Nakao, T.; Ong, H.J.; Onishi, T.K.; Suzuki, D.; Suzuki, H.; Suzuki, M.K. [University of Tokyo, Department of Physics, Tokyo (Japan); Kubo, T.; Aoi, N.; Fukuda, N.; Motobayashi, T.; Yamada, K.N.; Sakurai, H. [RIKEN, RIKEN Nishina Center, Saitama (Japan); Banerjee, V.; Chakrabarti, A. [Variable Energy Cyclotron Centre, Kolkata (India); Kubono, S.; Yamaguchi, H. [University of Tokyo, Center for Nuclear Study, Tokyo (Japan); Nakabayashi, T.; Nakamura, T.; Okumura, T. [Tokyo Institute of Technology, Department of Physics, Tokyo (Japan); Teranishi, T. [Kyushu University, Department of Physics, Fukuoka (Japan)

    2009-12-15

    {beta} -decay spectroscopy on a T{sub z}=-2 proton-rich nucleus {sup 24}Si was performed. The decay scheme of {sup 24}Si was reconstructed by the {beta} -delayed {gamma} -ray and proton measurements. Two {beta} branches to the bound 1{sub 1}{sup +} and 1{sub 2}{sup +} states in {sup 24}Al were observed for the first time. The observation of the allowed transition firmly established the spin-parity assignment for the 1{sub 2}{sup +} states. The branching ratios to the 1{sub 1}{sup +} and 1{sub 2}{sup +} states were determined to be 31(4)% and 23.9(15)%, respectively. The branching ratios to three unbound states in {sup 24}Al including a new level at 6.735MeV were also determined for the first time. The level structure of {sup 24}Al was compared with its mirror nucleus {sup 24}Na. The Thomas-Ehrman shift on the 1{sub 2}{sup +} state indicates s -wave dominance in the state as well as a characteristic behavior of the weakly bound s-wave proton in {sup 24}Al. (orig.)

  10. Tests of the standard electroweak model in beta decay

    Energy Technology Data Exchange (ETDEWEB)

    Severijns, N.; Beck, M. [Universite Catholique de Louvain (UCL), Louvain-la-Neuve (Belgium); Naviliat-Cuncic, O. [Caen Univ., CNRS-ENSI, 14 (France). Lab. de Physique Corpusculaire

    2006-05-15

    We review the current status of precision measurements in allowed nuclear beta decay, including neutron decay, with emphasis on their potential to look for new physics beyond the standard electroweak model. The experimental results are interpreted in the framework of phenomenological model-independent descriptions of nuclear beta decay as well as in some specific extensions of the standard model. The values of the standard couplings and the constraints on the exotic couplings of the general beta decay Hamiltonian are updated. For the ratio between the axial and the vector couplings we obtain C{sub A},/C{sub V} = -1.26992(69) under the standard model assumptions. Particular attention is devoted to the discussion of the sensitivity and complementarity of different precision experiments in direct beta decay. The prospects and the impact of recent developments of precision tools and of high intensity low energy beams are also addressed. (author)

  11. Beta-delayed proton emission from {sup 20}Mg

    Energy Technology Data Exchange (ETDEWEB)

    Lund, M.V.; Fynbo, H.O.U.; Howard, A.M.; Kirsebom, O.S.; Munch, M.; Riisager, K. [Aarhus University, Department of Physics and Astronomy, Aarhus C (Denmark); Andreyev, A.; Wadsworth, R. [University of York, Department of Physics, York (United Kingdom); Borge, M.J.G. [CSIC, Instituto de Estructura de la Materia, Madrid (Spain); CERN, ISOLDE, PH Department, Geneva 23 (Switzerland); Cederkaell, J. [Lund University, Department of Nuclear Physics, Lund (Sweden); Witte, H. de; Huyse, M.; Duppen, P. van [Instituut voor Kern- en Stralingsfysica, KU-Leuven, Leuven (Belgium); Fraile, L.M.; Vedia, V. [Universidad Complutense de Madrid, CEI Moncloa, Facultad de Ciencias Fisicas, Madrid (Spain); Greenlees, P.T.; Konki, J.; Rahkila, P. [University of Helsinki, Helsinki Institute of Physics, Helsinki (Finland); University of Jyvaeskylae, Department of Physics, Jyvaeskylae (Finland); Harkness-Brennan, L.J.; Judson, D.S.; Page, R.D. [University of Liverpool, Department of Physics, Oliver Lodge Laboratory, Liverpool (United Kingdom); Jonson, B.; Lindberg, S.; Nilsson, T. [Chalmers University of Technology, Department of Physics, Goeteborg (Sweden); Kurcewicz, J.; Madurga, M.; Rapisarda, E. [CERN, ISOLDE, PH Department, Geneva (Switzerland); Lazarus, I.; Pucknell, V. [STFC Daresbury, Daresbury, Warrington (United Kingdom); Lica, R. [CERN, ISOLDE, PH Department, Geneva (Switzerland); ' ' Horia Hulubei' ' National Institute of Physics and Nuclear Engineering, Magurele (Romania); Marginean, N.; Marginean, R.; Mihai, C.; Negret, A.; Pascu, S.; Rotaru, F.; Stanoiu, M.; Turturica, A. [' ' Horia Hulubei' ' National Institute of Physics and Nuclear Engineering, Magurele (Romania); Marroquin, I.; Nacher, E.; Perea, A.; Tengblad, O. [CSIC, Instituto de Estructura de la Materia, Madrid (Spain); Sotty, C. [Instituut voor Kern- en Stralingsfysica, KU-Leuven, Leuven (Belgium); ' ' Horia Hulubei' ' National Institute of Physics and Nuclear Engineering, Magurele (Romania); Warr, N. [Universitaet Koeln, Institut fuer Kernphysik, Koeln (Germany); Collaboration: IDS Collaboration

    2016-10-15

    Beta-delayed proton emission from {sup 20} Mg has been measured at ISOLDE, CERN, with the ISOLDE Decay Station (IDS) setup including both charged-particle and gamma-ray detection capabilities. A total of 27 delayed proton branches were measured including seven so far unobserved. An updated decay scheme, including three new resonances above the proton separation energy in {sup 20}Na and more precise resonance energies, is presented. Beta-decay feeding to two resonances above the Isobaric Analogue State (IAS) in {sup 20}Na is observed. This may allow studies of the 4032.9(2.4) keV resonance in {sup 19}Ne through the beta decay of {sup 20}Mg, which is important for the astrophysically relevant reaction {sup 15}O(α, γ){sup 19}Ne. Beta-delayed protons were used to obtain a more precise value for the half-life of {sup 20}Mg, 91.4(1.0) ms. (orig.)

  12. Tests of the standard electroweak model in beta decay

    International Nuclear Information System (INIS)

    Severijns, N.; Beck, M.; Naviliat-Cuncic, O.

    2006-05-01

    We review the current status of precision measurements in allowed nuclear beta decay, including neutron decay, with emphasis on their potential to look for new physics beyond the standard electroweak model. The experimental results are interpreted in the framework of phenomenological model-independent descriptions of nuclear beta decay as well as in some specific extensions of the standard model. The values of the standard couplings and the constraints on the exotic couplings of the general beta decay Hamiltonian are updated. For the ratio between the axial and the vector couplings we obtain C A ,/C V = -1.26992(69) under the standard model assumptions. Particular attention is devoted to the discussion of the sensitivity and complementarity of different precision experiments in direct beta decay. The prospects and the impact of recent developments of precision tools and of high intensity low energy beams are also addressed. (author)

  13. Identification of active anti-inflammatory principles of beta- beta ...

    African Journals Online (AJOL)

    chromatography. Components of the extracts were identified by thin layer chromatography (TLC) scanner and UV-visible spectroscopy, using scopoletin as standard. Results: ... basic coumarin skeleton ring structure reduce ... Figure 2: Thin-layer chromatogram: (1) Ethanol extract; (2) Dichloromethane fraction; (3) Beta-beta.

  14. Improved limits on beta(-) and beta(-) decays of Ca-48

    Czech Academy of Sciences Publication Activity Database

    Bakalyarov, A.; Balysh, A.; Barabash, AS.; Beneš, P.; Briancon, C.; Brudanin, V. B.; Čermák, P.; Egorov, V.; Hubert, F.; Hubert, P.; Korolev, NA.; Kosjakov, VN.; Kovalík, Alojz; Lebedev, NA.; Novgorodov, A. F.; Rukhadze, NI.; Štekl, NI.; Timkin, VV.; Veleshko, IE.; Vylov, T.; Umatov, VI.

    2002-01-01

    Roč. 76, č. 9 (2002), s. 545-547 ISSN 0021-3640 Institutional research plan: CEZ:AV0Z1048901 Keywords : beta decay * double beta decay * Ca-48 Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 1.483, year: 2002

  15. Contribution to the study of {beta} disintegration and of nuclear structure using experiments on certain {beta}-{gamma} cascades: 198{sub Au}, 86{sub Rb}, 170{sub Tm}; Contribution a l'etude de la desintegration beta et a l'etude de la structure nucleaire a l'aide d'experiences sur certaines cascades beta-gamma: 198{sub Au}, 86{sub Rb}, 170{sub Tm}

    Energy Technology Data Exchange (ETDEWEB)

    Lachkar, J. [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes; Paris-11 Univ., fabulte des Sciences 91 - Orsay (France)

    1969-07-01

    {beta}{gamma} directional angular correlations and shapes of inner beta spectra leading to the first excited level of the final nucleus enable one to determine the nuclear matrix elements typical of the {beta} transition. In the three observed first forbidden cases: {sup 170}Tm, {sup 86}Rb, {sup 198}Au, these matrix elements do not confirm the independent shell model theory. Other hypotheses are then suggested and discussed. (author) [French] Les experiences de correlation angulaire {beta}{gamma} et l'etude du spectre {beta} conduisant au premier niveau excite du noyau final permettent de determiner les elements de matrices nucleaires caracteristiques de cette transition. Dans les trois cas etudies (transitions une fois interdites): {sup 170}Tm, {sup 86}Rb, {sup 198}Au, ces elements de matrices ne peuvent etre retrouves a l'aide du modele en couches et a particules independantes. D'autres hypotheses sont alors emises et discutees. (auteur)

  16. Contribution to the study of {beta} disintegration and of nuclear structure using experiments on certain {beta}-{gamma} cascades: 198{sub Au}, 86{sub Rb}, 170{sub Tm}; Contribution a l'etude de la desintegration beta et a l'etude de la structure nucleaire a l'aide d'experiences sur certaines cascades beta-gamma: 198{sub Au}, 86{sub Rb}, 170{sub Tm}

    Energy Technology Data Exchange (ETDEWEB)

    Lachkar, J [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes; Paris-11 Univ., fabulte des Sciences 91 - Orsay (France)

    1969-07-01

    {beta}{gamma} directional angular correlations and shapes of inner beta spectra leading to the first excited level of the final nucleus enable one to determine the nuclear matrix elements typical of the {beta} transition. In the three observed first forbidden cases: {sup 170}Tm, {sup 86}Rb, {sup 198}Au, these matrix elements do not confirm the independent shell model theory. Other hypotheses are then suggested and discussed. (author) [French] Les experiences de correlation angulaire {beta}{gamma} et l'etude du spectre {beta} conduisant au premier niveau excite du noyau final permettent de determiner les elements de matrices nucleaires caracteristiques de cette transition. Dans les trois cas etudies (transitions une fois interdites): {sup 170}Tm, {sup 86}Rb, {sup 198}Au, ces elements de matrices ne peuvent etre retrouves a l'aide du modele en couches et a particules independantes. D'autres hypotheses sont alors emises et discutees. (auteur)

  17. Conversion of beta-methylbutyric acid to beta-hydroxy-beta-methylbutyric acid by Galactomyces reessii.

    OpenAIRE

    Lee, I Y; Nissen, S L; Rosazza, J P

    1997-01-01

    beta-Hydroxy-beta-methylbutyric acid (HMB) has been shown to increase strength and lean mass gains in humans undergoing resistance-exercise training. HMB is currently marketed as a calcium salt of HMB, and thus, environmentally sound and inexpensive methods of manufacture are being sought. This study investigates the microbial conversion of beta-methylbutyric acid (MBA) to HMB by cultures of Galactomyces reessii. Optimal concentrations of MBA were in the range of 5 to 20 g/liter for HMB produ...

  18. Isolation and characterization of BetaM protein encoded by ATP1B4 - a unique member of the Na,K-ATPase {beta}-subunit gene family

    Energy Technology Data Exchange (ETDEWEB)

    Pestov, Nikolay B. [Department of Physiology and Pharmacology, University of Toledo College of Medicine, 3000 Arlington Ave., Toledo, OH 43614 (United States); Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117997 (Russian Federation); Zhao, Hao [Department of Physiology and Pharmacology, University of Toledo College of Medicine, 3000 Arlington Ave., Toledo, OH 43614 (United States); Basrur, Venkatesha [Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109 (United States); Modyanov, Nikolai N., E-mail: nikolai.modyanov@utoledo.edu [Department of Physiology and Pharmacology, University of Toledo College of Medicine, 3000 Arlington Ave., Toledo, OH 43614 (United States)

    2011-09-09

    also characterized by SELDI-TOF mass spectrometry before and after deglycosylation. This allowed us to determine that the carbohydrate moiety of BetaM has molecular mass 5.9 kDa and consists of short high-mannose type N-glycans. The results of direct analysis of the purified native eutherian BetaM protein provide first insights into structural properties underlying its entirely new evolutionarily acquired functions.

  19. Metabolic clearance rate and urinary clearance of purified beta-core

    International Nuclear Information System (INIS)

    Wehmann, R.E.; Blithe, D.L.; Flack, M.R.; Nisula, B.C.

    1989-01-01

    We injected a highly purified preparation of the beta-core molecule, a fragment of hCG beta excreted in pregnancy urine, into five men and three women to determine its kinetic parameters, MCR, and urinary clearance. The beta-core molecule was distributed in an initial volume [1950 +/- 156 (mean +/- SEM) mL/m2 body surface area] approximately equal to the estimated plasma volume. Its disappearance was multiexponential on a semilogarithmic plot, with a rapid phase t1/2 of 3.5 +/- 0.7 min and a slow phase t1/2 of 22.4 +/- 4.2 min. The transit time (the mean time spent by a molecule of beta-core in transit) was 20.6 +/- 2.1 min. The MCR was 192.0 +/- 8.0 mL/min.m2 body surface area. About 5% of the injected dose of beta-core was excreted into the urine in the first 30 min after injection, and low levels of excretion persisted for up to 7 days. The urinary clearance rate of beta-core was 13.7 +/- 1.4 mL/min.m2, accounting for about 8% of the elimination of beta-core from the plasma. The beta-core immunoreactivity in serum and urine was characterized by gel filtration and three independent RIA systems to show that its properties were indistinguishable from those of the injected beta-core. Serum levels of beta-core in pregnant women were less than 0.2 ng/mL, while the amounts excreted in their urine were as much as 5 mg/day. Based on these clearance parameters of beta-core in normal subjects, less than 0.2% of the beta-core excreted in pregnancy urine is derived by urinary clearance of plasma beta-core. Therefore, more than 99% of the beta-core excreted in pregnancy urine is derived from beta-core in a compartment separate from plasma. In particular, these data indicate that there is relatively little placental secretion of beta-core into plasma and that placental secretion does not account for the vast majority of beta-core in pregnancy urine

  20. Clean Air Markets - Allowances Query Wizard

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Allowances Query Wizard is part of a suite of Clean Air Markets-related tools that are accessible at http://camddataandmaps.epa.gov/gdm/index.cfm. The Allowances...

  1. Allowance Holdings and Transfers Data Inventory

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Allowance Holdings and Transfers Data Inventory contains measured data on holdings and transactions of allowances under the NOx Budget Trading Program (NBP), a...

  2. 49 CFR 19.27 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... applicable to the entity incurring the costs. Thus, allowability of costs incurred by State, local or... Circular A-87, “Cost Principles for State and Local Governments.” The allowability of costs incurred by non... Principles for Non-Profit Organizations.” The allowability of costs incurred by institutions of higher...

  3. 29 CFR 95.27 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... cost principles applicable to the entity incurring the costs. Thus, allowability of costs incurred by... Governments.” The allowability of costs incurred by non-profit organizations is determined in accordance with... Organizations.” The allowability of costs incurred by institutions of higher education is determined in...

  4. 24 CFR 84.27 - Allowable costs.

    Science.gov (United States)

    2010-04-01

    ... to the entity incurring the costs. Thus, allowability of costs incurred by State, local or federally..., “Cost Principles for State and Local Governments.” The allowability of costs incurred by non-profit...-Profit Organizations.” The allowability of costs incurred by institutions of higher education is...

  5. 7 CFR 550.25 - Allowable costs.

    Science.gov (United States)

    2010-01-01

    ... cost principles applicable to the entity incurring the costs. Thus, allowability of costs incurred by... at 2 CFR part 225. The allowability of costs incurred by non-profit organizations is determined in... at 2 CFR part 230. The allowability of costs incurred by institutions of higher education is...

  6. 36 CFR 1210.27 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... applicable to the entity incurring the costs. Thus, allowability of costs incurred by State, local or... Circular A-87, “Cost Principles for State and Local Governments.” The allowability of costs incurred by non... Principles for Non-Profit Organizations.” The allowability of costs incurred by institutions of higher...

  7. 7 CFR 3019.27 - Allowable costs.

    Science.gov (United States)

    2010-01-01

    ... applicable to the entity incurring the costs. Thus, allowability of costs incurred by State, local or... Circular A-87, “Cost Principles for State and Local Governments.” The allowability of costs incurred by non... Principles for Non-Profit Organizations.” The allowability of costs incurred by institutions of higher...

  8. 46 CFR 154.428 - Allowable stress.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Allowable stress. 154.428 Section 154.428 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR... § 154.428 Allowable stress. The membrane tank and the supporting insulation must have allowable stresses...

  9. 46 CFR 154.447 - Allowable stress.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Allowable stress. 154.447 Section 154.447 Shipping COAST... Tank Type B § 154.447 Allowable stress. (a) An independent tank type B designed from bodies of revolution must have allowable stresses 3 determined by the following formulae: 3 See Appendix B for stress...

  10. 42 CFR 417.802 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Allowable costs. 417.802 Section 417.802 Public... PLANS Health Care Prepayment Plans § 417.802 Allowable costs. (a) General rule. The costs that are considered allowable for HCPP reimbursement are the same as those for reasonable cost HMOs and CMPs specified...

  11. 45 CFR 1180.56 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Allowable costs. 1180.56 Section 1180.56 Public... by a Grantee General Administrative Responsibilities § 1180.56 Allowable costs. (a) Determination of costs allowable under a grant is made in accordance with government-wide cost principles in applicable...

  12. 50 CFR 85.41 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Allowable costs. 85.41 Section 85.41... Use/Acceptance of Funds § 85.41 Allowable costs. (a) Allowable grant costs are limited to those costs... applicable Federal cost principles in 43 CFR 12.60(b). Purchase of informational signs, program signs, and...

  13. 34 CFR 675.33 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... costs. An institution's share of allowable costs may be in cash or in the form of services. The... 34 Education 3 2010-07-01 2010-07-01 false Allowable costs. 675.33 Section 675.33 Education... costs. (a)(1) Allowable and unallowable costs. Except as provided in paragraph (a)(2) of this section...

  14. The best-beta CAPM

    NARCIS (Netherlands)

    Zou, L.

    2006-01-01

    The issue of 'best-beta' arises as soon as potential errors in the Sharpe-Lintner-Black capital asset pricing model (CAPM) are acknowledged. By incorporating a target variable into the investor preferences, this study derives a best-beta CAPM (BCAPM) that maintains the CAPM's theoretical appeal and

  15. Beta decay of Cu-56

    NARCIS (Netherlands)

    Borcea, R; Aysto, J; Caurier, E; Dendooven, P; Doring, J; Gierlik, M; Gorska, M; Grawe, H; Hellstrom, M; Janas, Z; Jokinen, A; Karny, M; Kirchner, R; La Commara, M; Langanke, K; Martinez-Pinedo, G; Mayet, P; Nieminen, A; Nowacki, F; Penttila, H; Plochocki, A; Rejmund, M; Roeckl, E; Schlegel, C; Schmidt, K; Schwengner, R; Sawicka, M

    2001-01-01

    The proton-rich isotope Cu-56 was produced at the GSI On-Line Mass Separator by means of the Si-28(S-32, p3n) fusion-evaporation reaction. Its beta -decay properties were studied by detecting beta -delayed gamma rays and protons. A half-Life of 93 +/- 3 ms was determined for Cu-56. Compared to the

  16. Review of the beta situation

    International Nuclear Information System (INIS)

    Sheffield, J.

    1982-01-01

    This note lists some of the possible causes of beta limitation in tokamak and discusses what is known and what is involved in investigating them. The motivation for preparing this note is the observed degradation of confinement with increasing beta poloidal β/sub p/ and beam power P/sub b/ in ISX-B

  17. Supporting Transition

    Science.gov (United States)

    Qureshi, Asima; Petrucco, James

    2018-01-01

    Meadowbrook Primary School has explored the use of The Teacher Assessment in Primary Science (TAPS) to support transition, initially for transfer to secondary school and now for transition from Early Years Foundation Stage (EYFS) into Key Stage 1 (ages 5-7). This article will consider an example of a secondary transition project and discuss the…

  18. Beta-delayed neutron decay of $^{33}$Na

    CERN Document Server

    Radivojevic, Z; Caurier, E; Cederkäll, J; Courtin, S; Dessagne, P; Jokinen, A; Knipper, A; Le Scornet, G; Lyapin, V G; Miehé, C; Nowacki, F; Nummela, S; Oinonen, M; Poirier, E; Ramdhane, M; Trzaska, W H; Walter, G; Äystö, J

    2002-01-01

    Beta-delayed neutron decay of /sup 33/Na has been studied using the on-line mass separator ISOLDE. The delayed neutron spectra were measured by time-of-flight technique using fast scintillators. Two main neutron groups at 800(60) and 1020(80) keV were assigned to the /sup 33/Na decay, showing evidence for strong feeding of states at about 4 MeV in /sup 33/Mg. By simultaneous beta - gamma -n counting the delayed neutron emission probabilities P/sub 1n/ = 47(6)% and P /sub 2n/ = 13(3)% were determined. The half-life value for /sup 33 /Na, T/sub 1/2/ = 8.0(3) ms, was measured by three different techniques, one employing identifying gamma transitions and two employing beta and neutron counting. (21 refs).

  19. High beta and second stability region transport and stability analysis

    International Nuclear Information System (INIS)

    1991-01-01

    This document describes ideal and resistive MHD studies of high-beta plasmas and of the second stability region. Significant progress is reported on the resistive stability properties of high beta poloidal ''supershot'' discharges. For these studies initial profiles were taken from the TRANSP code which is used extensively to analyze experimental data. When an ad hoc method of removing the finite pressure stabilization of tearing modes is implemented it is shown that there is substantial agreement between MHD stability computation and experiment. In particular, the mode structures observed experimentally are consistent with the predictions of the resistive MHD model. We also report on resistive stability near the transition to the second region in TFTR. Tearing modes associated with a nearby infernal mode may explain the increase in MHD activity seen in high beta supershots and which impede the realization of Q∼1. We also report on a collaborative study with PPPL involving sawtooth stabilization with ICRF

  20. RAVEN Beta Release

    International Nuclear Information System (INIS)

    Rabiti, Cristian; Alfonsi, Andrea; Cogliati, Joshua Joseph; Mandelli, Diego; Kinoshita, Robert Arthur; Wang, Congjian; Maljovec, Daniel Patrick; Talbot, Paul William

    2016-01-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  1. RAVEN Beta Release

    Energy Technology Data Exchange (ETDEWEB)

    Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Alfonsi, Andrea [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cogliati, Joshua Joseph [Idaho National Lab. (INL), Idaho Falls, ID (United States); Mandelli, Diego [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kinoshita, Robert Arthur [Idaho National Lab. (INL), Idaho Falls, ID (United States); Wang, Congjian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Maljovec, Daniel Patrick [Idaho National Lab. (INL), Idaho Falls, ID (United States); Talbot, Paul William [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-02-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  2. LUCIFER: Scintillating bolometers for the search of Neutrinoless Double Beta Decay

    Energy Technology Data Exchange (ETDEWEB)

    Vignati, M. [Sapienza Universita di Roma and INFN Sezione di Roma, Roma, I-00185 (Italy)

    2012-08-15

    The nature of neutrino mass is one of the frontier problems of particle physics. Neutrinoless Double Beta Decay (0{nu}DBD) is a powerful tool to measure the neutrino mass and to test possible extensions of the Standard Model. Bolometers are excellent detectors to search for this rare decay, thanks to their good energy resolution and to the low background conditions in which they can operate. The current challenge consists in the reduction of the background, represented by environmental {gamma}'s and {alpha}'s, in view of a zero background experiment. We present the LUCIFER R and D, funded by an European grant, in which the background can be reduced by an order of magnitude with respect to the present generation experiments. The technique is based on the simultaneous bolometric measurement of the heat and of the scintillation light produced by a particle, that allows to discriminate between {beta} and {alpha} particles. The {gamma} background is reduced by choosing 0{nu}DBD candidate isotopes with transition energy above the environmental {gamma}'s spectrum. The prospect of this R and D are discussed.

  3. Secondary structure determination of human. beta. -endorphin by /sup 1/H NMR spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Lichtarge, O.; Jardetzky, O.; Li, C.H.

    1987-09-08

    The /sup 1/H NMR spectra of human ..beta..-endorphin indicate that the peptide exists in random-coil form in aqueous solution but becomes helical in mixed solvent. Thermal denaturation NMR experiments show that in water there is no transition between 24 and 75/sup 0/C, while a slow noncooperative thermal unfolding is observed in a 60% methanol-40% water mixed solvent in the same temperature range. These findings are consistent with circular dichroism studies by other workers concluding that ..beta..-endorphin is a random coil in water but that it forms 50% ..cap alpha..-helix or more in mixed solvents. The peptide in the mixed water-methanol solvent was further studied by correlated spectroscopy (COSY) and nuclear Overhauser effect spectroscopy (NOESY) experiments. These allow a complete set of assignments to be made and establish two distinct stretches over which the solvent induces formation of ..cap alpha..-helices: the first occurs between Tyr-1 and Thr-12 and the second between Leu-14 and extending to Lys-28. There is evidence that the latter is capped by a turn occurring between Lys-28 and Glu-31. These helices form at the enkephalin receptor binding site, which is at the amino terminus, and at the morphine receptor binding site, located at the carboxyl terminus. The findings suggest that these two receptors may specifically recognize ..cap alpha..-helices.

  4. Measurement of the $\\beta$-asymmetry parameter in $^{35}$Ar decay with a laser polarized beam

    CERN Multimedia

    With this proposal we request beam time for the first two phases of a project that aims at measuring the $\\beta$-asymmetry parameter of the mirror $\\beta$-decay branch in $^{35}$Ar using an optically polarized Ar atom beam. The final goal of the experiment is to measure this parameter to a precision of 0.5%. This will allow the most precise determination of the V$_{ud}$ quark mixing matrix element from all the mirror transitions with an absolute uncertainty of 0.0007. The proposal will be presented in phases and we ask here 11 shifts (7 on-line + 4 off-line) for phase 1 and 15 shifts (6 on-line and 9 off-line) for phase 2. Phase 1 aims at establishing the optimal laser polarization scheme as well as the best implantation host for maintaining the polarization. Phase 2 aims at enhancing the beam polarization by removing the unpolarized part of the beam using re-ionization.

  5. The study of the properties of nuclei far from the beta stability line

    International Nuclear Information System (INIS)

    Lizurej, H.I.

    1980-01-01

    A complex of setups for measuring the lifetime of excited states of nuclei by the method of delayed electron-gamma and gamma-gamma coincidences in the range 10 -10 -10 -6 s is presented. The methods allowing for a substantial increase in the accuracy and efficiency of obtaining experimental data are developed. The procedures of measuring and analysing the multicomponent beta spectra with taking into account the instrumental effect which distorts the measured spectra are developed. Results of investigating the positron decay and determining the mass difference Qsub(B)+ for nuclei with Tsub(1/2)>20 min by the method of measuring the positron end-point energy are presented. The nano- and subnanosecond isomers for short-lived isotopes far from the beta stability line have been investigated. Probabilities of the electromagnetic transitions which depopulate the low-lying excited states in 151 Tb, 153 Dy, 160 Tm, sup(157,159,161)Er have been determined and analysed. (author)

  6. Interactions between two beta-sheets. Energetics of beta/beta packing in proteins.

    Science.gov (United States)

    Chou, K C; Némethy, G; Rumsey, S; Tuttle, R W; Scheraga, H A

    1986-04-20

    The analysis of the interactions between regularly folded segments of the polypeptide chain contributes to an understanding of the energetics of protein folding. Conformational energy-minimization calculations have been carried out to determine the favorable ways of packing two right-twisted beta-sheets. The packing of two five-stranded beta-sheets was investigated, with the strands having the composition CH3CO-(L-Ile)6-NHCH3 in one beta-sheet and CH3CO-(L-Val)6-NHCH3 in the other. Two distinct classes of low-energy packing arrangements were found. In the class with lowest energies, the strands of the two beta-sheets are aligned nearly parallel (or antiparallel) with each other, with a preference for a negative orientation angle, because this arrangement corresponds to the best complementary packing of the two twisted saddle-shaped beta-sheets. In the second class, with higher interaction energies, the strands of the two beta-sheets are oriented nearly perpendicular to each other. While the surfaces of the two beta-sheets are not complementary in this arrangement, there is good packing between the corner of one beta-sheet and the interior part of the surface of the other, resulting in a favorable energy of packing. Both classes correspond to frequently observed orientations of beta-sheets in proteins. In proteins, the second class of packing is usually observed when the two beta-sheets are covalently linked, i.e. when a polypeptide strand passes from one beta-sheet to the other, but we have shown here that a large contribution to the stabilization of this packing arrangement arises from noncovalent interactions.

  7. Melting of a beta-Hairpin Peptide Using Isotope-Edited 2D IR Spectroscopy and Simulations

    NARCIS (Netherlands)

    Smith, Adam W.; Lessing, Joshua; Ganim, Ziad; Peng, Chunte Sam; Tokmakoff, Andrei; Roy, Santanu; Jansen, Thomas L. C.; Knoester, Jasper

    2010-01-01

    Isotope-edited two-dimensional infrared spectroscopy has been used! to characterize the conformational heterogeneity of the beta-hairpin peptide TrpZip2 (17.2) across its thermal unfolding transition Four isotopologues were synthesized to probe hydrogen bonding and solvent exposure of the beta-turn

  8. Melting of a beta-hairpin peptide using isotope-edited 2D IR spectroscopy and simulations.

    NARCIS (Netherlands)

    Smith, A.W.; Lessing, J.; Ganim, Z.; Peng, C.S.; Tokmakoff, A.; Roy, S.; Jansen, T.L.Th.A.; Knoester, J.

    2010-01-01

    Isotope-edited two-dimensional infrared spectroscopy has been used to characterize the conformational heterogeneity of the beta-hairpin peptide TrpZip2 (TZ2) across its thermal unfolding transition. Four isotopologues were synthesized to probe hydrogen bonding and solvent exposure of the beta-turn

  9. First identification of the 0{sub 2}{sup +} state in {sup 30}Mg via its E0 transition

    Energy Technology Data Exchange (ETDEWEB)

    Schwerdtfeger, Wolfgang Norbert Erik

    2008-08-28

    The known 1789 keV level in {sup 30}Mg turned out to be a candidate for the 0{sub 2}{sup +} state due to its long lifetime of 3.9(4) ns and the absence of a {gamma} transition to the ground state. This triggered our search on the 0{sub 2}{sup +}{yields}0{sub 1}{sup +} E0 transition in {sup 30}Mg following the {beta} decay of {sup 30}Na: {beta} decay electrons were detected in a scintillation detector, while conversion electrons were focused onto a cooled Si(Li) detector using a Mini-Orange and detected with high resolution, which simultaneously suppresses the high background of {beta} decay electrons. Due to the large Q value of the {beta} decay of {sup 30}Na (17.3 MeV) the suppression of the coincident background induced by high-energy {gamma} rays and subsequently Compton-scattered electrons turned out to be the key challenge for the success of this experiment. In order to optimise the background suppression and thus the sensitivity to weak E0 transitions, offline test measurements using an {sup 90}Y and a {sup 152}Eu source were performed together with GEANT4 simulations. Resulting from these test measurements a highly sensitive experimental setup was designed and built, consequently minimising the amount of high-Z material in the target chamber, reducing X-ray production. As a by-product from test measurements the database value of the half-life of the 0{sub 2}{sup +} state in {sup 90}Zr could be corrected by more than 30 % to be t{sub 1/2}=41(1) ns. Finally, in a {beta} decay experiment at the ISOLDE facility at CERN the 0{sub 2}{sup +}{yields}0{sub 1}{sup +} E0 transition in {sup 30}Mg could be identified at the expected transition energy of 1788 keV proving for the first time shape coexistence at the borderline of the 'Island of Inversion'. This identification allows to determine the electric monopole strength as {rho}{sup 2}(E0)=26.2(7.5) x 10{sup -3}, indicating a rather weak mixing between the states in two potential minima in a simplified two

  10. Comparative study of {beta} decays and of the model of the layers for the nucleus with odd a; Etude comparee des desintegrations {beta} et du modele des couches pour les noyaux de a impair

    Energy Technology Data Exchange (ETDEWEB)

    Trocheris, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1953-07-01

    The systematic comparison of {beta} decays of the cores of number of odd mass with the predictions of the modal of Mrs. Mayer on spins and parities, has already been made by several authors. It is taken in the present work with more recent experimental data and with a method of classification of the {beta} transitions. A simultaneous comparison to the experience of the model of the layers and the theory of the {beta} transitions can serve to verify one and the other too. In the present work, it appeared more fruitful to try to verify the model of the layers with the help of the very established theory of the {beta} transitions. One will look to verify and perfect the models of the layers for transitions between fundamental states or isomers of the cores. (M.B.) [French] La comparaison systematique des desintegrations {beta} des noyaux de nombre de masse impair avec les predictions du modale de Mme MAYER sur les spins et les parites, a deja ete faite par plusieurs auteurs. Elle est reprise dans le present travail avec des donnees experimentales plus recentes et avec une methode de classification des transitions {beta}. Une comparaison simultanee a l'experience du modele des couches et de la theorie des transitions {beta} peut, a priori, servir a verifier egalement l'un et l'autre. Dans le present travail, il a paru plus fructueux de chercher a verifier le modele des couches a l'aide de la theorie bien etablie des transitions {beta}. On cherchera de verifier et de perfectionner le modele des couches pour les transitions entre etats fondamentaux ou isomeres des noyaux. (M.B.)

  11. Derivatives of the Incomplete Beta Function

    Directory of Open Access Journals (Sweden)

    Robert J. Boik

    1998-03-01

    Full Text Available The incomplete beta function is defined as where Beta(p, q is the beta function. Dutka (1981 gave a history of the development and numerical evaluation of this function. In this article, an algorithm for computing first and second derivatives of Ix,p,q with respect to p and q is described. The algorithm is useful, for example, when fitting parameters to a censored beta, truncated beta, or a truncated beta-binomial model.

  12. Rapid method of identification of {beta}-ray emitters and of {beta}-radioactive impurity dosage (1961); Methode rapide d'identification des emetteurs-{beta} et de dosage d'impuretes radioactives-{beta} (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Le Gallic, Y; Legrand, J; Grinberg, B [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    We describe a simple method of radioactive analysis, which allows an accurate determination of maximal energies of {beta}-emitters, and detection and titration of radioactive impurities in radionuclides as well. The method described, which uses a plastic scintillator, is based on the fact that the curve obtained by plotting the number of pulses measured against the threshold is a straight line, in the case of pure {beta}-emitters. We then derive a simple relation between the data of this straight line and the maximal energy of the {beta}-spectrum of the radionuclide under consideration. (authors) [French] Description d'une methode simple d'analyse radioactive, permettant de determiner avec precision l'energie maximum des emetteurs-{beta}, ainsi que de deceler et de doser les impuretes radioactives dans un radionuclide. La technique decrite utilise un scintillateur plastique. On exploite le fait que la courbe du nombre d'impulsions mesurees, en fonction du seuil de discrimination, est une droite, pour un emetteur-{beta} pur. Une relation simple entre les caracteristiques de cette droite et l'energie maximum du spectre-{beta} du radionuclide, correspondant, a ete etablie. (auteurs)

  13. Development of beta reference radiations

    International Nuclear Information System (INIS)

    Wan Zhaoyong; Cai Shanyu; Li Yanbo; Yin Wei; Feng Jiamin; Sun Yuhua; Li Yongqiang

    1997-09-01

    A system of beta reference radiation has been developed, that is composed of 740 MBq 147 Pm beta source, 74 MBq and 740 MBq 90 Sr + 90 Y β sources, compensation filters, a source handling tool, a source jig, spacing bars, a shutter, a control unit and a beta dose meter calibration stand. For 740 MBq 147 Pm and 74 MBq 90 Sr + 90 Y beta reference radiations with compensation filters and 740 MBq 90 Sr + 90 Y beta reference radiation without compensation filter, at 20 cm, 30 cm and 30 cm distance separately; the residual energy of maximum is 0.14 MeV, 1.98 MeV and 2.18 MeV separately; the absorbed dose to tissue D (0.07) is 1.547 mGy/h (1996-05-20), 5.037 mGy/h (1996-05-10) and 93.57 mGy/h (1996-05-15) separately; the total uncertainty is 3.0%, 1.7% and 1.7% separately. For the first and the second beta reference radiation, the dose rate variability in the area of 18 cm diameter in the plane perpendicular to the beta-ray beam axis is within +-6% and +-3% separately. (3 refs., 2 tabs., 8 figs.)

  14. A semiconductor beta ray spectrometer

    International Nuclear Information System (INIS)

    Bom, V.R.

    1987-01-01

    Measurement of energy spectra of beta particles emitted from nuclei in beta-decay processes provides information concerning the mass difference of these nuclei between initial and final state. Moreover, experimental beta spectra yield information on the feeding of the levels in the daughter nucleus. Such data are valuable in the construction and checking of the level schemes. This thesis describes the design, construction, testing and usage of a detector for the accurate measurement of the mentioned spectra. In ch. 2 the design and construction of the beta spectrometer, which uses a hyper-pure germanium crystal for energy determination, is described. A simple wire chamber is used to discriminate beta particles from gamma radiation. Disadvantages arise from the large amounts of scattered beta particles deforming the continua. A method is described to minimize the scattering. In ch. 3 some theoretical aspects of data analysis are described and the results of Monte-Carlo simulations of the summation of annihilation radiation are compared with experiments. Ch. 4 comprises the results of the measurements of the beta decay energies of 103-108 In. 87 refs.; 34 figs.; 7 tabs

  15. BETA (Bitter Electromagnet Testing Apparatus)

    Science.gov (United States)

    Bates, Evan M.; Birmingham, William J.; Rivera, William F.; Romero-Talamas, Carlos A.

    2017-10-01

    The Bitter Electromagnet Testing Apparatus (BETA) is a 1-Tesla (T) prototype of the 10-T Adjustable Long Pulse High-Field Apparatus (ALPHA). These water-cooled resistive magnets use high DC currents to produce strong uniform magnetic fields. Presented here is the successful completion of the BETA project and experimental results validating analytical magnet designing methods developed at the Dusty Plasma Laboratory (DPL). BETA's final design specifications will be highlighted which include electromagnetic, thermal and stress analyses. The magnet core design will be explained which include: Bitter Arcs, helix starters, and clamping annuli. The final version of the magnet's vessel and cooling system are also presented, as well as the electrical system of BETA, which is composed of a unique solid-state breaker circuit. Experimental results presented will show the operation of BETA at 1 T. The results are compared to both analytical design methods and finite element analysis calculations. We also explore the steady state maximums and theoretical limits of BETA's design. The completion of BETA validates the design and manufacturing techniques that will be used in the succeeding magnet, ALPHA.

  16. Double Charge Exchange Reactions and Double Beta Decay

    Science.gov (United States)

    Auerbach, N.

    2018-05-01

    The subject of this presentation is at the forefront of nuclear physics, namely double beta decay. In particular one is most interested in the neutrinoless process of double beta decay, when the decay proceeds without the emission of two neutrinos. The observation of such decay would mean that the lepton conservation symmetry is violated and that the neutrinos are of Majorana type, meaning that they are their own anti-particles. The life time of this process has two unknowns, the mass of the neutrino and the nuclear matrix element. Determining the nuclear matrix element and knowing the cross-section well will set limits on the neutrino mass. There is a concentrated effort among the nuclear physics community to calculate this matrix element. Usually these matrix elements are a very small part of the total strength of the transition operators involved in the process. There is no simple way to “calibrate” the nuclear double beta decay matrix element. The double beta decay is a double charge exchange process, therefore it is proposed that double charge exchange reactions using ion projectiles on nuclei that are candidates for double beta decay, will provide additional necessary information about the nuclear matrix elements.

  17. Transitions between beta and gamma rhythms in neural systems

    DEFF Research Database (Denmark)

    Sosnovtseva, Olga; Setsinsky, D.; Fausbøll, Anders

    2002-01-01

    We study the coexistence of different rhythms in a local network of one inhibitory and two excitatory nerve cells for a wide range of the excitatory synapse strength and of the slow K+-channel conductance. The dynamic features of spike trains in the presence of noise are discussed. It is found...... that noise can both cause switching between different states and induce coherent firing events....

  18. Transitions between beta and gamma rhythms in neural systems

    DEFF Research Database (Denmark)

    Sosnovtseva, Olga; Setsinsky, D; Fausbøll, Anders

    2002-01-01

    We study the coexistence of different rhythms in a local network of one inhibitory and two excitatory nerve cells for a wide range of the excitatory synapse strength and of the slow K+-channel conductance. The dynamic features of spike trains in the presence of noise are discussed. It is found...

  19. The structure of nuclei far from beta stability

    International Nuclear Information System (INIS)

    Zganjar, E.F.

    1991-01-01

    This report discusses the structural of nuclei for from beta stability of the following isotopes: thallium isotopes; mercury isotopes; gold isotopes; platinum isotopes; iridium isotopes; the neutron deficient rare-earth, Z = 57-72 region, and the neutron deficient Z = 50-56 region; also discussed are in-beam spectroscopy in the A = 70 region and shape coexistence, intruder states, and EO transitions

  20. Inner bremsstrahlung accompanying beta decay of 170Tm

    International Nuclear Information System (INIS)

    Sanjeeviah, H.; Venkataramaiah, P.; Gundu Rao, K.S.

    1980-01-01

    The inner bremmsstrahlung (IB) spectrum accompanying beta decay of 170 Tm was measured using magnetic deflection technique. The raw spectrum was unfolded using the procedure of Liden and Starfelt. The unfolded IB spectrum was compared with the theories of Knipp and Uhlenbeck and Bloch; Lewis and Ford. Comparison was made with Ford and Martin theory in order to estimate the contribution of detour transitions to the IB spectrum of 170 Tm. (author)

  1. Beta-spectrometer with Si-detectors for the study of 144Ce-144Pr decays

    Science.gov (United States)

    Alexeev, I. E.; Bakhlanov, S. V.; Bazlov, N. V.; Chmel, E. A.; Derbin, A. V.; Drachnev, I. S.; Kotina, I. M.; Muratova, V. N.; Pilipenko, N. V.; Semyonov, D. A.; Unzhakov, E. V.; Yeremin, V. K.

    2018-05-01

    Here we present the specifications of a newly developed beta-spectrometer, based on full absorption Si(Li) detector and thin transmission detector, allowing one to perform efficient separation beta-radiation and accompanying X-rays and gamma radiation. Our method is based on registration of coincident events from both detectors. The spectrometer can be used for precision measurements of various beta-spectra, namely for the beta-spectrum shape study of 144Pr, which is considered to be an advantageous anti-neutrino source for sterile neutrino searches.

  2. A practical method for in-situ thickness determination using energy distribution of beta particles

    International Nuclear Information System (INIS)

    Yalcin, S.; Gurler, O.; Gundogdu, O.; Bradley, D.A.

    2012-01-01

    This paper discusses a method to determine the thickness of an absorber using the energy distribution of beta particles. An empirical relationship was obtained between the absorber thickness and the energy distribution of beta particles transmitted through. The thickness of a polyethylene radioactive source cover was determined by exploiting this relationship, which has largely been left unexploited allowing us to determine the in-situ cover thickness of beta sources in a fast, cheap and non-destructive way. - Highlights: ► A practical and in-situ unknown cover thickness determination ► Cheap and readily available compared to other techniques. ► Beta energy spectrum.

  3. Transition radiation and transition scattering

    International Nuclear Information System (INIS)

    Ginzburg, V.L.

    1982-01-01

    Transition radiation is a process of a rather general character. It occurs when some source, which does not have a proper frequency (for example, a charge) moves at a constant velocity in an inhomogeneous and (or) nonstationary medium or near such a medium. The simplest type of transition radiation takes place when a charge crosses a boundary between two media (the role of one of the media may be played by vacuum). In the case of periodic variation of the medium, transition radiation possesses some specific features (resonance transition radiation or transition scattering). Transition scattering occurs, in particular, when a permittivity wave falls onto an nonmoving (fixed) charge. Transition scattering is closely connected with transition bremsstrahlung radiation. All these transition processes are essential for plasma physics. Transition radiation and transition scattering have analogues outside the framework of electrodynamics (like in the case of Vavilov-Cherenkov radiation). In the present report the corresponding range of phenomena is elucidated, as far as possible, in a generally physical aspect. (Auth.)

  4. Schematic model studies of double beta decay processes

    International Nuclear Information System (INIS)

    Civitarese, O.

    1996-01-01

    Some features of the nuclear matrix elements, for double beta decay transitions to a final ground state and to a final excited one and two-quadrupole phonon states, are presented and discussed in the framework of a schematic model. The competition between spin-flip and non-spin-flip transitions on the relevant nuclear matrix elements, the effects due to proton-neutron pairing correlations and the effects due to the inclusion of exchange terms in the QRPA matrix are discussed. (Author)

  5. Experiments on double beta decay

    Energy Technology Data Exchange (ETDEWEB)

    Busto, J [Neuchatel Univ. (Switzerland). Inst. de Physique

    1996-11-01

    The Double Beta Decay, and especially ({beta}{beta}){sub 0{nu}} mode, is an excellent test of Standard Model as well as of neutrino physics. From experimental point of view, a very large number of different techniques are or have been used increasing the sensitivity of this experiments quite a lot (the factor of 10{sup 4} in the last 20 years). In future, in spite of several difficulties, the sensitivity would be increased further, keeping the interest of this very important process. (author) 4 figs., 5 tabs., 21 refs.

  6. Preventive Effects of Beta-Hydroxy-Beta-Methyl Butyrate

    OpenAIRE

    N. Ravanbakhsh; N. Torabi; M. Foadoddini

    2016-01-01

    Aims: One of the major factors in sudden cardiac arrest is the initiation and continuation of deadly arrhythmias during ischemia. It is known that beta-hydroxy-beta-methylbutyrate (HMB) has useful effects such as anti-inflammatory and anti-apoptosis effects in the skeletal muscles. The aim of this study was to investigate the preventive effects of HMB on the ventricular arrhythmias due to the ischemia. Materials & Methods: In the experimental study, 30 Wistar male rats were randomly div...

  7. Dosimetry of {beta} extensive sources; Dosimetria de fuentes {beta} extensas

    Energy Technology Data Exchange (ETDEWEB)

    Rojas C, E.L.; Lallena R, A.M. [Departamento de Fisica Moderna, Universidad de Granada, E-18071 Granada (Spain)

    2002-07-01

    In this work, we have been studied, making use of the Penelope Monte Carlo simulation code, the dosimetry of {beta} extensive sources in situations of spherical geometry including interfaces. These configurations are of interest in the treatment of the called cranealfaringyomes of some synovia leisure of knee and other problems of interest in medical physics. Therefore, its application can be extended toward problems of another areas with similar geometric situation and beta sources. (Author)

  8. 42 CFR 61.8 - Benefits: Stipends; dependency allowances; travel allowances; vacation.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Benefits: Stipends; dependency allowances; travel...; dependency allowances; travel allowances; vacation. Individuals awarded regular fellowships shall be entitled...) Stipend. (b) Dependency allowances. (c) When authorized in advance, separate allowances for travel. Such...

  9. 42 CFR 61.9 - Payments: Stipends; dependency allowances; travel allowances.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Payments: Stipends; dependency allowances; travel... FELLOWSHIPS, INTERNSHIPS, TRAINING FELLOWSHIPS Regular Fellowships § 61.9 Payments: Stipends; dependency allowances; travel allowances. Payments for stipends, dependency allowances, and the travel allowances...

  10. 33 CFR 136.235 - Compensation allowable.

    Science.gov (United States)

    2010-07-01

    ... allowable. The amount of compensation allowable is limited to the actual net reduction or loss of earnings or profits suffered. Calculations for net reductions or losses must clearly reflect adjustments for... available; (d) Any saved overhead or normal expenses not incurred as a result of the incident; and (e) State...

  11. 10 CFR 600.317 - Allowable costs.

    Science.gov (United States)

    2010-01-01

    ... to the type of entity incurring the cost as follows: (1) For-profit organizations. Allowability of costs incurred by for-profit organizations and those nonprofit organizations listed in Attachment C to... specifically authorized in the award document. (2) Other types of organizations. Allowability of costs incurred...

  12. 29 CFR 97.22 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... accounting standards that comply with cost principles acceptable to the Federal agency. [53 FR 8069, 8087... LOCAL GOVERNMENTS Post-Award Requirements Financial Administration § 97.22 Allowable costs. (a... increment above allowable costs) to the grantee or subgrantee. (b) Applicable cost principles. For each kind...

  13. 22 CFR 135.22 - Allowable costs.

    Science.gov (United States)

    2010-04-01

    ... Procedures, or uniform cost accounting standards that comply with cost principles acceptable to the Federal... AGREEMENTS TO STATE AND LOCAL GOVERNMENTS Post-Award Requirements Financial Administration § 135.22 Allowable... principles. For each kind of organization, there is a set of Federal principles for determining allowable...

  14. 34 CFR 74.27 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... Procedures or uniform cost accounting standards that comply with cost principles acceptable to ED. (b) The... OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial... principles for determining allowable costs. Allowability of costs are determined in accordance with the cost...

  15. 44 CFR 13.22 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... uniform cost accounting standards that comply with cost principles acceptable to the Federal agency. ... STATE AND LOCAL GOVERNMENTS Post-Award Requirements Financial Administration § 13.22 Allowable costs. (a... increment above allowable costs) to the grantee or subgrantee. (b) Applicable cost principles. For each kind...

  16. 24 CFR 85.22 - Allowable costs.

    Science.gov (United States)

    2010-04-01

    ... uniform cost accounting standards that comply with cost principles acceptable to the Federal agency. ... TRIBAL GOVERNMENTS Post-Award Requirements Financial Administration § 85.22 Allowable costs. (a... increment above allowable costs) to the grantee or subgrantee. (b) Applicable cost principles. For each kind...

  17. 36 CFR 1207.22 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... uniform cost accounting standards that comply with cost principles acceptable to the Federal agency. ... GOVERNMENTS Post-Award Requirements Financial Administration § 1207.22 Allowable costs. (a) Limitation on use... increment above allowable costs) to the grantee or subgrantee. (b) Applicable cost principles. For each kind...

  18. 32 CFR 33.22 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... accounting standards that comply with cost principles acceptable to the Federal agency. ... Post-Award Requirements Financial Administration § 33.22 Allowable costs. (a) Limitation on use of... allowable costs) to the grantee or subgrantee. (b) Applicable cost principles. For each kind of organization...

  19. 20 CFR 631.84 - Allowable projects.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Allowable projects. 631.84 Section 631.84... THE JOB TRAINING PARTNERSHIP ACT Disaster Relief Employment Assistance § 631.84 Allowable projects...) Shall be used exclusively to provide employment on projects that provide food, clothing, shelter and...

  20. 45 CFR 2541.220 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... accounting standards that comply with cost principles acceptable to the Federal agency. ... the grantee or subgrantee. (b) Applicable cost principles. For each kind of organization, there is a set of Federal principles for determining allowable costs. Allowable costs will be determined in...

  1. 15 CFR 14.27 - Allowable costs.

    Science.gov (United States)

    2010-01-01

    ... GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, OTHER NON-PROFIT, AND COMMERCIAL ORGANIZATIONS Post-Award Requirements Financial and Program Management § 14.27 Allowable costs. For each kind of... Organizations.” The allowability of costs incurred by institutions of higher education is determined in...

  2. 45 CFR 2543.27 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 2543.27 Allowable costs. For each kind... Organizations.” The allowability of costs incurred by institutions of higher education is determined in...

  3. 28 CFR 70.27 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... AND AGREEMENTS (INCLUDING SUBAWARDS) WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 70.27 Allowable costs. (a... Organizations.” The allowability of costs incurred by institutions of higher education is determined in...

  4. 38 CFR 49.27 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 49.27 Allowable...-Profit Organizations.” The allowability of costs incurred by institutions of higher education is...

  5. 20 CFR 435.27 - Allowable costs.

    Science.gov (United States)

    2010-04-01

    ... AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, OTHER NON-PROFIT ORGANIZATIONS, AND COMMERCIAL ORGANIZATIONS Post-Award Requirements Financial and Program Management § 435.27 Allowable costs. For each kind... Organizations.” (c) Allowability of costs incurred by institutions of higher education is determined in...

  6. 40 CFR 30.27 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 30.27 Allowable...-Profit Organizations.” The allowability of costs incurred by institutions of higher education is...

  7. Double Beta Decay

    International Nuclear Information System (INIS)

    Fiorini, Ettore

    2008-01-01

    The importance of neutrinoless Double Beta Decay (DBD) is stressed in view of the recent results of experiments on neutrino oscillations which indicate that the difference between the squared masses of two neutrinos of different flavours is finite [For a recent review including neutrino properties and recent results see: Review of Particle Physics, J. of Phys. G: Nuclear and Particle Physics 33, 1]. As a consequence the mass of at least one neutrino has to be different from zero and it becomes imperative to determine its absolute value. The various experimental techniques to search for DBD are discussed together with the difficult problems of the evaluation of the corresponding nuclear matrix elements. The upper limits on neutrino mass coming from the results of the various experiments are reported together with the indication for a non zero value by one of them not confirmed so far. The two presently running experiments on neutrinoless DBD are briefly described together with the already approved or designed second generation searches aiming to reach the values on the absolute neutrino mass indicated by the results on neutrino oscillations

  8. Is neutrinoless double beta decay suppressed

    International Nuclear Information System (INIS)

    Tomoda, T.

    1989-01-01

    Much effort has been devoted to the study of nuclear double beta decay, since the observation of a neutrinoless double beta (OνΒΒ) decay would be clear evidence that the electron neutrino is a Majorana particle. The OνΒΒ decay is caused by a finite Majorana neutrino mass and/or an admixture of right-handed leptonic currents. In order to relate these quantities to OνΒΒ decay rates, we need nuclear matrix elements, which are model dependent. One of the possibilities of testing nuclear models employed in such analysis is to calculate the experimentally known rates of ΒΒ decay with emission of two neutrinos (2νΒΒ decay) which occurs independently of the nature of the neutrino. There was a long-standing difficulty in such attempts that the calculated 2νΒΒ decay rates turned out to be always too large by one to two orders of magnitude. Trying to overcome such difficulty, Klapdor and Grotz as well as Vogel and Zirnbauer showed in their calculation using schematic effective interactions such that 2νΒΒ decay rates can get reduced considerably due to the nuclear ground state correlations. This paper reports that the suppression is ascribed to that of the virtual Gamow-Teller transitions from the excited 1 + states of the intermediate odd-odd -even nucleus

  9. Double beta decay: a new formalism

    International Nuclear Information System (INIS)

    Hirsch, J.; Krmpotic, F.

    1990-01-01

    A study is made of the validity of those methods consisting in an average of solutions from initial and final solutions within the quasi-particle random phase approximation (QRPA) for double beta decay. A new method is developed that works with a single QRPA equation for the intermediate nucleus in which the correlations of the ground state for β - transitions are β + and vice versa. Numerical results agree in the different formulations, which avails the known averaging procedures while showing the greater operative simplicity of the proposed method for the case of the two neutrino mode in which the diagonalization process may be substituted by a matrix inversion. (Author). 13 refs., 1 fig., 1 tab

  10. Conditional Relationship Between Beta and Return in the US Stock Market

    Directory of Open Access Journals (Sweden)

    Bing XIAO

    2016-04-01

    Full Text Available According to the CAPM, risk is measured by the beta, and the relation between required expected return and beta is linear. This paper examines the conditional relationship between beta and return in the US stock market. The conditional covariances and variances used to estimate beta are modeled as an ARCH process. The beta return relationship is tested upon the sign of the excess market return. The implication of the sign of the excess market return follows Morelli (2011. This study shows the importance of recognizing the sign of the excess market return when testing the beta-return relationship. The approach also allows us to distinguish the size effect and the effect of economic cycles.

  11. Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function

    DEFF Research Database (Denmark)

    Gimond, C; van Der Flier, A; van Delft, S

    1999-01-01

    different beta1-null cell lines, epithelial GE11 and fibroblast-like GD25 cells. Expression of beta1A or the cytoplasmic splice variant beta1D, induced the disruption of intercellular adherens junctions and cell scattering in both GE11 and GD25 cells. In GE11 cells, the morphological change correlated...... for a complete morphological transition towards the spindle-shaped fibroblast-like phenotype. The expression of an interleukin-2 receptor (IL2R)-beta1A chimera and its incorporation into focal adhesions also induced the disruption of cadherin-based adhesions and the reorganization of ECM-cell contacts...

  12. Molecular effects in the neutrino mass determination from beta-decay of the tritium molecule

    International Nuclear Information System (INIS)

    Fackler, O.; Jeziorski, B.; Kolos, W.; Szalewicz, K.; Monkhorst, H.J.; Mugge, M.

    1986-03-01

    Molecular final state energies and transition probabilities have been computed for beta-decay of the tritium molecule. The results are of sufficient accuracy to make a determination of the electron neutrino rest mass with an error not exceeding a few tenths of an electron volt. Effects of approximate models of tritium beta-decay on the neutrino mass determination are discussed. 14 refs., 3 figs., 1 tab

  13. The search for Majorana neutrinos with neutrinoless double beta decays: From CUORICINO to LUCIFER experiment

    Energy Technology Data Exchange (ETDEWEB)

    Bellini, F. [Dipartimento di Fisica, Sapienza Universita di Roma, Roma I-00185 (Italy) and INFN - Sezione di Roma, Roma I-00185 (Italy)

    2012-11-20

    The study of neutrino properties is one of the fundamental challenges in particle physics nowadays. Fifty years of investigations established that neutrinos are massive but the absolute mass scale has not yet been measured. Moreover its true nature is still unknown. Is the neutrino its own antiparticle (thus violating the lepton number) as proposed by Majorana in 1937? The only way to probe the neutrino nature is through the observation of Neutrinoless Double Beta Decay (0{nu}{beta}{beta}), a very rare spontaneous nuclear transition which emits two electrons and no neutrinos. In this paper, after a brief introduction to the theoretical framework of Majorana's neutrino, a presentation of experimental challenges posed by 0{nu}{beta}{beta} search will be given as well as an overview of present status and future perpectives of experiments.

  14. Formulary considerations in selection of beta-blockers.

    Science.gov (United States)

    Yedinak, K C

    1993-08-01

    Selection of beta-adrenergic blockers for formulary addition can be a difficult task, especially with the increasing availability of new beta-blockers, as well as the numerous differences in pharmacodynamic and pharmacokinetic properties of currently available agents. Nevertheless, appropriate evaluation of the important characteristics of beta-blockers should allow selection of the most cost-effective agents for formulary addition. Most importantly, differences in efficacy, product formulation and cost should be carefully considered when making formulary decisions. Notably, evidence from clinical trials indicates differences in efficacy among beta-blockers for post-myocardial infarction prophylaxis, situational anxiety, essential tremor, thyrotoxicosis, migraine prophylaxis and prevention of bleeding associated with oesophageal varices. For many clinical situations, it is also important to select an effective agent that is available in both an oral and intravenous formulation, especially for cardioprotection after acute myocardial infarction and for use in supraventricular arrhythmias. In addition, availability of sustained release products and generic formulations should be considered for their potential to increase compliance and decrease cost, respectively. Comparative drug costs, as well as costs associated with decreased compliance, should also be carefully evaluated. Differences in beta-receptor selectivity, duration of action and presence of intrinsic sympathomimetic activity (ISA) are also important considerations in the selection of beta-blockers for formulary consideration. Although degree of selectivity is relative, beta 1-selective agents may be less likely to induce bronchospasm in patients with chronic obstructive pulmonary disease (COPD) and may be less likely to affect glucose homeostasis in patients with diabetes mellitus. Duration of action of a beta-blocker is an important consideration for evaluation of efficacy throughout the recommended

  15. Generalized definitions of phase transitions

    International Nuclear Information System (INIS)

    Chomaz, Ph.; Gulminelli, F.

    2001-09-01

    We define a first order phase transition as a bimodality of the event distribution in the space of observations and we show that this is equivalent to a curvature anomaly of the thermodynamical potential and that it implies the Yang Lee behavior of the zeros of the partition sum. Moreover, it allows to study phase transitions out of equilibrium. (authors)

  16. The {beta}-decay Paul trap: A radiofrequency-quadrupole ion trap for precision {beta}-decay studies

    Energy Technology Data Exchange (ETDEWEB)

    Scielzo, N.D., E-mail: scielzo1@llnl.gov [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Li, G. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Department of Physics, McGill University, Montreal, Quebec, Canada H3A 2T8 (Canada); Sternberg, M.G.; Savard, G. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Department of Physics, University of Chicago, Chicago, Illinois 60637 (United States); Bertone, P.F. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Buchinger, F. [Department of Physics, McGill University, Montreal, Quebec, Canada H3A 2T8 (Canada); Caldwell, S. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Department of Physics, University of Chicago, Chicago, Illinois 60637 (United States); Clark, J.A. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Crawford, J. [Department of Physics, McGill University, Montreal, Quebec, Canada H3A 2T8 (Canada); Deibel, C.M. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Joint Institute for Nuclear Astrophysics, Michigan State University, East Lansing, Michigan 48824 (United States); Fallis, J. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Department of Physics and Astronomy, University of Manitoba, Winnipeg, Manitoba, Canada R3T 2N2 (Canada); Greene, J.P. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); and others

    2012-07-21

    The {beta}-decay Paul trap is a linear radiofrequency-quadrupole ion trap that has been developed for precision {beta}-decay studies. The design of the trap electrodes allows a variety of radiation detectors to surround the cloud of trapped ions. The momentum of the low-energy recoiling daughter nuclei following {beta} decay is negligibly perturbed by scattering and is available for study. This advantageous property of traps allows the kinematics of particles that are difficult or even impossible to directly detect to be precisely reconstructed using conservation of energy and momentum. An ion-trap system offers several advantages over atom traps, such as higher trapping efficiencies and element-independent capabilities. The first precision experiment using this system is a measurement of {beta}-decay angular correlations in the decay of {sup 8}Li performed by inferring the momentum of the neutrino from the kinematic shifts imparted to the breakup {alpha} particles. Many other {beta}-decay studies that would benefit from a determination of the nuclear recoil can be performed with this system.

  17. (beta-HC CG) in

    African Journals Online (AJOL)

    raoul

    Urothelial tumour samples were obtained from all the 86 patients requiring surgical ..... and/or urine beta HCG appears to be an efficient diagnostic marker for the ..... collected all urothelial tumour specimens for storage, cutting and staining.

  18. Beta-glucans and cholesterol

    Czech Academy of Sciences Publication Activity Database

    Šíma, Petr; Vannucci, Luca; Větvička, V.

    2017-01-01

    Roč. 41, č. 4 (2017), s. 1799-1808 ISSN 1107-3756 Institutional support: RVO:61388971 Keywords : cholesterol * beta-glucans * diet Subject RIV: EE - Microbiology, Virology OBOR OECD: Microbiology Impact factor: 2.341, year: 2016

  19. Radioisotope indicator, type BETA 2

    International Nuclear Information System (INIS)

    Duszanski, M.; Pankow, A.; Skwarczynski, B.

    1975-01-01

    The authors describe a radioisotope indicator, type BETA 2, constructed in the ZKMPW Works to be employed in mines for counting, checking, signalling the presence and positioning of cars, as well as monitoring the state of some other equipment. (author)

  20. Utility allowed returns and market extremes

    International Nuclear Information System (INIS)

    Murry, D.A.; Nan, G.D.; Harrington, B.M.

    1993-01-01

    In recent years interest rates have fluctuated from exceptionally high levels in the early 1980s to their current levels, the lowest in two decades. Observers and analysts generally have assumed that allowed returns by regulatory commissions follow the movement of interest rates; indeed some analysts use a risk premium method to estimate the cost of common equity, assuming a constant and linear relationship between interest rates and the cost of common equity. That suggests we could expect a relatively stable relationship between interest rates and allowed returns, as well. However, a simple comparison of allowed returns and interest rates shows that this is not the case in recent years. The relationship between market interest rates and the returns allowed by commissions varies and is obviously a great deal more complicated. Empirically, there appears to be only a narrow range where market interest rates significantly affect the allowed returns on common stock set by state commissions, at least for electric and combination utilities. If rates are at historically low levels, allowed returns based largely on market rates will hasten subsequent rate filings, and commissions appear to look beyond the low rate levels. Conversely, it appears that regulators do not let historically high market rates determine allowed returns either. At either high or low interest levels, caution seems to be the policy

  1. The future(s) of emission allowances

    International Nuclear Information System (INIS)

    Rosenzweig, K.M.; Villarreal, J.A.

    1993-01-01

    The Clean Air Act Amendments of 1990 (CAAA) established a sulfur dioxide emission allowance system to be implemented by the US Environmental Protection Agency (EPA). Under the two-phase implementation of the program, electric utilities responsible for approximately 70 percent of SO 2 emissions in the United States will be issued emission allowances, each representing authorization to emit one ton of sulfur dioxide during a specified calendar year or a later year. Allowances will be issued to utilities with electric-generating units affected by the CAAA limits, as well as to certain entities which may choose to opt-in to the program. Each utility or other emission source must hold a number of allowances at least equal to its total SO 2 emissions during any given year. Unused allowances may be sold, traded, or held in inventory for use against SO 2 emissions in future years. Anyone can buy and hold allowances, including affected utilities, non-utility companies, SO 2 allowances brokers and dealers, environmental groups, and individuals. During Phase I of the program, allowances equivalent to approximately 6.4 million tons of SO 2 emissions will be allocated annually to a group of 110 large, high-SO 2 -emitting power plants. In Phase II, virtually all power-generating utilities (representing approximately 99.4 percent of total US utility emissions) will be subject to the program. The number of allowances issued will increase to approximately 8.9 million a year, with certain special allocations raising the actual number issued to 9.48 million between the years 2000 to 2009, and 8.95 million yearly thereafter. Thus, the CAAA goal of annual emissions of 9 million tons should be achieved by 2010, when virtually all US emission sources will be participating in the program

  2. Double beta decay searches with thermal detectors

    International Nuclear Information System (INIS)

    Pirro, Stefano

    2006-01-01

    Double beta decay searches have become more and more important in the last few years. The 'second generation' experiments will allow to explore the inverse hierarchy region but, due to the uncertainties in the nuclear matrix elements, none of them will be able to cover completely the allowed region. Thus the need to investigate different DBD emitters becomes more important. The bolometric technique is only one able to study different nuclei with the proper energy resolution, key point for the future experiments. The possibility to reject the natural background arising from fast neutrons and alpha particles was recently directly proved with thermal bolometers, using the double read out (heat and scintillation). This new technique offers the possibility to reach background levels two orders of magnitude smaller with respect to the ones of the next planned experiments, aiming the possibility to investigate direct hierarchy region. (author)

  3. Recombinant Innovation and Endogenous Transitions

    OpenAIRE

    Koen Frenken; Luis R. Izquierdo; Paolo Zeppini

    2012-01-01

    We propose a model of technological transitions based on two different types of innovations. Branching innovations refer to technological improvements along a particular path, while recombinant innovations represent fusions of multiple paths. Recombinant innovations create “short-cuts” which reduce switching costs allowing agents to escape a technological lock-in. As a result, recombinant innovations speed up technological progress allowing transitions that are impossible with only branching ...

  4. Keynes, family allowances and Keynesian economic policy

    OpenAIRE

    Pressman, Steven

    2014-01-01

    This paper provides a short history of family allowances and documents the fact that Keynes supported family allowances as early as the 1920s, continuing through the 1930s and early 1940s. Keynes saw this policy as a way to help households raise their children and also as a way to increase consumption without reducing business investment. The paper goes on to argue that a policy of family allowances is consistent with Keynesian economics. Finally, the paper uses the Luxembourg Income Study to...

  5. Transition Metal-Free Selective Double sp(3) C-H Oxidation of Cyclic Amines to 3-Alkoxyamine Lactams.

    Science.gov (United States)

    Osorio-Nieto, Urbano; Chamorro-Arenas, Delfino; Quintero, Leticia; Höpfl, Herbert; Sartillo-Piscil, Fernando

    2016-09-16

    The first chemical method for selective dual sp(3) C-H functionalization at the alpha-and beta positions of cyclic amines to their corresponding 3-alkoxyamine lactams is reported. Unlike traditional Cα-H oxidation of amines to amides mediated by transition metals, the present protocol, which involves the use of NaClO2/TEMPO/NaClO in either aqueous or organic solvent, not only allows the Cα-H oxidation but also the subsequent functionalization of the unreactive β-methylene group in an unprecedented tandem fashion and using environmentally friendly reactants.

  6. A beta skin dose monitor using an Eberline RO-2 ion chamber

    International Nuclear Information System (INIS)

    Jester, W.A.; Levine, S.H.; Lin, T.J.; Hock, R.

    1994-01-01

    The authors have developed a portable beta skin dose monitor that uses an Eberline RO-2trademark ion chamber. The development was based, in part, upon the previous development of a beta skin dose monitor employing silicon detectors. In this current work, the two entrance windows of the RO-2 were replaced by windows having a total mass thickness of 1.74 mg/cm 2 . A two section source-detector holder was constructed. One section fastens to the RO-2 and holds the detector at the right position to determine the contact skin dose from beta emitters located on surfaces. A second section attaches to the first, and provides fixed counting geometry for radioactive samples such as hot particles. The first section also contains a slide mechanism that allows the placement of absorbers of zero (0), 8.38, and 1000 mg/cm 2 between the detector window and the beta source. The detector response to these absorbers allows for the determination of beta skin dose. The system was modeled using a Monte Carlo beta attenuation code computing the beta skin dose to RO-2 detector response as a function of absorber thickness, average beta energy, source diameter and source position. Using the RO-2 reading from each of the three absorber configurations allows the calculation of beta skin dose and the average beta energy. The results of these calculations were confirmed through the use of three massless radioactive beta sources, traceable to the National Institute of Standards and Technology, and several utility-supplied hot particles having well-established contact skin doses. An extrapolation chamber was also used to confirm the results obtained from this monitor. This system is now use at the Pennsylvania Power and Light (PP and L) Company, the project sponsor. ((orig.))

  7. Milestoning with transition memory

    Science.gov (United States)

    Hawk, Alexander T.; Makarov, Dmitrii E.

    2011-12-01

    Milestoning is a method used to calculate the kinetics and thermodynamics of molecular processes occurring on time scales that are not accessible to brute force molecular dynamics (MD). In milestoning, the conformation space of the system is sectioned by hypersurfaces (milestones), an ensemble of trajectories is initialized on each milestone, and MD simulations are performed to calculate transitions between milestones. The transition probabilities and transition time distributions are then used to model the dynamics of the system with a Markov renewal process, wherein a long trajectory of the system is approximated as a succession of independent transitions between milestones. This approximation is justified if the transition probabilities and transition times are statistically independent. In practice, this amounts to a requirement that milestones are spaced such that trajectories lose position and velocity memory between subsequent transitions. Unfortunately, limiting the number of milestones limits both the resolution at which a system's properties can be analyzed, and the computational speedup achieved by the method. We propose a generalized milestoning procedure, milestoning with transition memory (MTM), which accounts for memory of previous transitions made by the system. When a reaction coordinate is used to define the milestones, the MTM procedure can be carried out at no significant additional expense as compared to conventional milestoning. To test MTM, we have applied its version that allows for the memory of the previous step to the toy model of a polymer chain undergoing Langevin dynamics in solution. We have computed the mean first passage time for the chain to attain a cyclic conformation and found that the number of milestones that can be used, without incurring significant errors in the first passage time is at least 8 times that permitted by conventional milestoning. We further demonstrate that, unlike conventional milestoning, MTM permits

  8. Maximum allowable load on wheeled mobile manipulators

    International Nuclear Information System (INIS)

    Habibnejad Korayem, M.; Ghariblu, H.

    2003-01-01

    This paper develops a computational technique for finding the maximum allowable load of mobile manipulator during a given trajectory. The maximum allowable loads which can be achieved by a mobile manipulator during a given trajectory are limited by the number of factors; probably the dynamic properties of mobile base and mounted manipulator, their actuator limitations and additional constraints applied to resolving the redundancy are the most important factors. To resolve extra D.O.F introduced by the base mobility, additional constraint functions are proposed directly in the task space of mobile manipulator. Finally, in two numerical examples involving a two-link planar manipulator mounted on a differentially driven mobile base, application of the method to determining maximum allowable load is verified. The simulation results demonstrates the maximum allowable load on a desired trajectory has not a unique value and directly depends on the additional constraint functions which applies to resolve the motion redundancy

  9. 33 CFR 136.223 - Compensation allowable.

    Science.gov (United States)

    2010-07-01

    ...) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS... allowable under paragraph (a) of this section must be reduced by— (1) All compensation made available to the... under § 136.235. Government Revenues ...

  10. Phase transitions

    CERN Document Server

    Sole, Ricard V; Solé, Ricard V; Solé, Ricard V; Sol, Ricard V; Solé, Ricard V

    2011-01-01

    Phase transitions--changes between different states of organization in a complex system--have long helped to explain physics concepts, such as why water freezes into a solid or boils to become a gas. How might phase transitions shed light on important problems in biological and ecological complex systems? Exploring the origins and implications of sudden changes in nature and society, Phase Transitions examines different dynamical behaviors in a broad range of complex systems. Using a compelling set of examples, from gene networks and ant colonies to human language and the degradation of diverse ecosystems, the book illustrates the power of simple models to reveal how phase transitions occur. Introductory chapters provide the critical concepts and the simplest mathematical techniques required to study phase transitions. In a series of example-driven chapters, Ricard Solé shows how such concepts and techniques can be applied to the analysis and prediction of complex system behavior, including the origins of ...

  11. Beta Instability and Stochastic Market Weights

    OpenAIRE

    David H. Goldenberg

    1985-01-01

    An argument is given for individual firm beta instability based upon the stochastic character of the market weights defining the market portfolio and the constancy of its beta. This argument is generalized to market weighted portfolios and the form of the stochastic process generating betas is linked to that of the market return process. The implications of this analysis for adequacy of models of beta nonstationarity and estimation of betas are considered in light of the available empirical e...

  12. Elaboration of supports for beta emitting sources (with vyns); Elaboracion de soportes para fuentes emisoras beta (con vyns)

    Energy Technology Data Exchange (ETDEWEB)

    Cortes P, A.; Torre O, J. De la; Tejera R, A.; Becerril V, A.; Bribiesca S, L

    1990-04-15

    The Laboratory of Radioactive patterns account with a 4 {pi}{beta}-{gamma} coincidence system of recent acquisition with which absolute measures of radioactive activity with uncertainties of the order of 0.1% can be made. Since the coincidence method for the activity measure consists on detecting to the particle and the photon corresponding to oneself nuclear disintegration, it is necessary to elaborate special radioactive sources on thin supports, in order to allowing the maximum possible fluence of {beta} particles ({approx} 100%). This work a technique for the elaboration of these sources and for the measure of the thickness of the walls of the support is presented. (Author)

  13. First direct observation of bound-state beta-decay. Measurements of branching and lifetime of {sup 207}Tl{sup 81+} fragments

    Energy Technology Data Exchange (ETDEWEB)

    Boutin, D.

    2005-08-01

    The first experimental observation of bound-state beta-decay showed, that due solely to the electron stripping, a stable nuclide, e.g. {sup 163}Dy, became unstable. Also a drastic modification of the half-life of bare {sup 187}Re, from 4.12(2) x 10{sup 10} years down to 32.9(20) years, could be observed. It was mainly due to the possibility for the mother nuclide to decay into a previously inaccessible nuclear level of the daughter nuclide. It was proposed to study a nuclide where this decay mode was competing with continuum-state beta-decay, in order to measure their respective branchings. The ratio {beta}{sub b}/{beta}{sub c} could also be evaluated for the first time. {sup 207}Tl was chosen due to its high atomic number, and Q-value of about 1.4 MeV, small enough to enhance the {beta}{sub b} probability and large enough to allow the use of time-resolved Schottky Mass Spectrometry (SMS) to study the evolution of mother and bound-state beta-decay daughter ions. The decay properties of the ground state and isomeric state of {sup 207}Tl{sup 81+} have been investigated at the GSI accelerator facility in two separate experiments. For the first time {beta}-decay where the electron could go either to a bound state (atomic orbitals) and lead to {sup 207}Pb{sup 81+} as a daughter nuclide, or to a continuum state and lead to {sup 207}Pb{sup 82+}, has been observed. The respective branchings of these two processes could be measured as well. The deduced total nuclear half-life of 255(17) s for {sup 207}Tl{sup 81+}, was slightly modified with respect to the half-life of the neutral atom of 286(2) s. It was nevertheless in very good agreement with calculations based on the assumption that the beta-decay was following an allowed type of transition. The branching {beta}{sub b}/{beta}{sub c}=0.192(20), was also in very good agreement with the same calculations. The application of stochastic precooling allowed to observe in addition the 1348 keV short-lived isomeric state of {sup

  14. Recent status of the studies of nuclear masses and {beta}-decay

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, Masami [Waseda Univ., Tokyo (Japan). Advanced Research Center for Science and Engineering

    1996-05-01

    The recent status of the above studies was explained, especially, nuclear masses were described from the aspect of probability theory and that of {beta}-decay suggested that the first forbidden transition was hindered between the ground states. We have to study various systematics in order to know the mass surface, Way-Yamada-Matumoto type systematics is better to check the experimental nuclear masses. The gross theory is very useful to understand the general aspect of {beta}-decay. The understanding method of mass surface, systematic check of mass and hindrance of the first forbidden transition at rank 1 were explained. (S.Y.)

  15. Tumor-produced, active Interleukin-1 {beta} regulates gene expression in carcinoma-associated fibroblasts

    Energy Technology Data Exchange (ETDEWEB)

    Dudas, Jozsef, E-mail: Jozsef.Dudas@i-med.ac.at [Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria); Fullar, Alexandra, E-mail: fullarsz@gmail.com [Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria); 1st Institute of Pathology and Experimental Cancer Research, Semmelweis University, Ulloei ut 26, H-1085 Budapest (Hungary); Bitsche, Mario, E-mail: Mario.Bitsche@i-med.ac.at [Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria); Schartinger, Volker, E-mail: Volker.Schartinger@i-med.ac.at [Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria); Kovalszky, Ilona, E-mail: koval@korb1.sote.hu [1st Institute of Pathology and Experimental Cancer Research, Semmelweis University, Ulloei ut 26, H-1085 Budapest (Hungary); Sprinzl, Georg Mathias, E-mail: Georg.Sprinzl@i-med.ac.at [Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria); Riechelmann, Herbert, E-mail: Herbert.Riechelmann@i-med.ac.at [Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria)

    2011-09-10

    Recently we described a co-culture model of periodontal ligament (PDL) fibroblasts and SCC-25 lingual squamous carcinoma cells, which resulted in conversion of normal fibroblasts into carcinoma-associated fibroblasts (CAFs), and in epithelial-mesenchymal transition (EMT) of SCC-25 cells. We have found a constitutive high interleukin-1{beta} (IL1-{beta}) expression in SCC-25 cells in normal and in co-cultured conditions. In our hypothesis a constitutive IL1-{beta} expression in SCC-25 regulates gene expression in fibroblasts during co-culture. Co-cultures were performed between PDL fibroblasts and SCC-25 cells with and without dexamethasone (DEX) treatment; IL1-{beta} processing was investigated in SCC-25 cells, tumor cells and PDL fibroblasts were treated with IL1-{beta}. IL1-{beta} signaling was investigated by western blot and immunocytochemistry. IL1-{beta}-regulated genes were analyzed by real-time qPCR. SCC-25 cells produced 16 kD active IL1-{beta}, its receptor was upregulated in PDL fibroblasts during co-culture, which induced phosphorylation of interleukin-1 receptor-associated kinase-1 (IRAK-1), and nuclear translocalization of NF{kappa}B{alpha}. Several genes, including interferon regulatory factor 1 (IRF1) interleukin-6 (IL-6) and prostaglandin-endoperoxide synthase 2 (COX-2) were induced in CAFs during co-culture. The most enhanced induction was found for IL-6 and COX-2. Treatment of PDL fibroblasts with IL1-{beta} reproduced a time- and dose-dependent upregulation of IL1-receptor, IL-6 and COX-2. A further proof was achieved by DEX inhibition for IL1-{beta}-stimulated IL-6 and COX-2 gene expression. Constitutive expression of IL1-{beta} in the tumor cells leads to IL1-{beta}-stimulated gene expression changes in tumor-associated fibroblasts, which are involved in tumor progression. -- Graphical abstract: SCC-25 cells produce active, processed IL1-{beta}. PDL fibroblasts possess receptor for IL1-{beta}, and its expression is increased 4.56-times in the

  16. Emission allowances -- Long-term price trend

    International Nuclear Information System (INIS)

    Lennox, F.H.

    1994-01-01

    Estimated trends in emission allowance (EA) values have been of interest to all those affected by the Clean Air Act Amendments of 1990 since it became law in 1990. The authors published estimates of the values of EAs in December 1991, and revised their estimate in November 1992. The summary trends of the 1992 estimate is shown here. General estimates such as these are no longer useful. Everyone directly involved in complying with the Act or in buying and selling allowances has developed their own outlook on EA values. Many recent trades have been publicized. The prices from the first auction are also well known. Therefore this article is concerned only with what might happening the long-run. Once Phase 2 compliance is essentially complete and emissions roughly match Emission Allowance allocations of some 9.8 million tons annually, what pressures will there be on prices? What will be the direction of values after Phase 2 is in balance?

  17. 19 CFR 18.6 - Short shipments; shortages; entry and allowance.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Short shipments; shortages; entry and allowance...; DEPARTMENT OF THE TREASURY TRANSPORTATION IN BOND AND MERCHANDISE IN TRANSIT General Provisions § 18.6 Short shipments; shortages; entry and allowance. (a) When there has been a short shipment and the short-shipped...

  18. Tradable allowances in a restructuring electric industry

    International Nuclear Information System (INIS)

    Tschirhart, J.

    1999-01-01

    The SO 2 tradable allowance program has been introduced into an electric industry undergoing dramatic changes. Entry of nonutilities into the industry and the emergence of stranded costs are two major changes that are shown to have an impact on the market for allowances and the industry's incentives to switch to cleaner fuels. The degree of impact depends on the extent to which consumers bypass traditional utilities and buy from entrants, and on public utility commission policies regarding the recovery of stranded costs. In turn, the amount of stranded costs depends on fuel switching. The results follow from simulations of a two-utility model that illustrate the qualitative effects of changing policies

  19. Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5).

    Science.gov (United States)

    Zannetti, Antonella; Del Vecchio, Silvana; Iommelli, Francesca; Del Gatto, Annarita; De Luca, Stefania; Zaccaro, Laura; Papaccioli, Angela; Sommella, Jvana; Panico, Mariarosaria; Speranza, Antonio; Grieco, Paolo; Novellino, Ettore; Saviano, Michele; Pedone, Carlo; Salvatore, Marco

    2009-08-15

    To test whether a novel bifunctional chimeric peptide comprising a cyclic Arg-Gly-Asp pentapeptide covalently bound to an echistatin domain can discriminate alpha(v)beta(3) from alpha(v)beta(5) integrin, thus allowing the in vivo selective visualization of alpha(v)beta(3) expression by single-photon and positron emission tomography (PET) imaging. The chimeric peptide was preliminarily tested for inhibition of alpha(v)beta(3)-dependent cell adhesion and competition of 125I-echistatin binding to membrane of stably transfected K562 cells expressing alpha(v)beta(3) (Kalpha(v)beta(3)) or alpha(v)beta(5) (Kalpha(v)beta(5)) integrin. The chimeric peptide was then conjugated with diethylenetriaminepentaacetic acid and labeled with 111In for single-photon imaging, whereas a one-step procedure was used for labeling the full-length peptide and a truncated derivative, lacking the last five C-terminal amino acids, with 18F for PET imaging. Nude mice bearing tumors from Kalpha(v)beta(3), Kalpha(v)beta(5), U87MG human glioblastoma, and A431 human epidermoid cells were subjected to single-photon and PET imaging. Adhesion and competitive binding assays showed that the novel chimeric peptide selectively binds to alpha(v)beta(3) integrin and does not cross-react with alpha(v)beta(5). In agreement with in vitro findings, single-photon and PET imaging studies showed that the radiolabeled chimeric peptide selectively localizes in tumor xenografts expressing alphavbeta3 and fails to accumulate in those expressing alpha(v)beta(5) integrin. When 18F-labeled truncated derivative was used for PET imaging, alphavbeta3- and alpha(v)beta(5)-expressing tumors were visualized, indicating that the five C-terminal amino acids are required to differentially bind the two integrins. Our findings indicate that the novel chimeric Arg-Gly-Asp peptide, having no cross-reaction with alphavbeta5 integrin, allows highly selective alphavbeta3 expression imaging and monitoring.

  20. Parallel multireference configuration interaction calculations on mini-beta-carotenes and beta-carotene.

    Science.gov (United States)

    Kleinschmidt, Martin; Marian, Christel M; Waletzke, Mirko; Grimme, Stefan

    2009-01-28

    presented. For beta-carotene, where these transition energies are known from experiment, excellent agreement with our calculations is observed.

  1. What are the potential benefits of clinical beta-cell imaging in diabetes mellitus?

    Science.gov (United States)

    Göke, Burkhard

    2010-05-01

    Previously, studies of the endocrine pancreatic beta-cell were mainly performed ex vivo by morphological means. This data supported the analysis of pathophysiological changes in the pancreatic islet during insults such as diabetes mellitus. Metabolic testing of the pancreatic islet by assaying hormone parameters such als plasma insulin or C-peptide combined with more or less sophisticated calculations allowed conclusions about states of insulin resistance or secretory failure. It also allowed certain correlations of endocrine function with beta-cell mass. Today, with firmer pathophysiological concepts about beta-cell failure, modern protocols of islet transplantation, and drugs on the market coming with promises of preservation or even expansion of beta-cell mass in diabetes mellitus it has become very attractive to search for tools measuring beta-cell mass, if possible even repeatingly in the same organism in vivo. From a clinical point of view, the potential of pancreatic beta-cell mass imaging technologies is looked upon with high expectations. Methodologically, the decisive question is whether it is likely that future beta-cell imaging will provide significant advantages over the metabolic methods already in hand. With new in vivo tools, studies of beta-cell mass and function may offer even new approaches stratifying patients to anti-diabetic therapies.

  2. Transit transparency.

    Science.gov (United States)

    2012-07-01

    Public transit agencies have employed intelligent systems for determining : schedules and routes and for monitoring the real-time location and status of their : vehicle fleets for nearly two decades. But until recently, the data generated by : daily ...

  3. 22 CFR 226.27 - Allowable costs.

    Science.gov (United States)

    2010-04-01

    ... Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Post-award Requirements Financial and Program Management § 226.27 Allowable costs. For each kind... organizations is determined in accordance with the provisions of OMB Circular A-122, “Cost Principles for Non...

  4. 13 CFR 143.22 - Allowable costs.

    Science.gov (United States)

    2010-01-01

    ... to that circular 48 CFR part 31. Contract Cost Principles and Procedures, or uniform cost accounting... Financial Administration § 143.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used... grantee or subgrantee. (b) Applicable cost principles. For each kind of organization, there is a set of...

  5. 38 CFR 43.22 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... accounting standards that comply with cost principles acceptable to the Federal agency. ... Requirements Financial Administration § 43.22 Allowable costs. (a) Limitation on use of funds. Grant funds may... the grantee or subgrantee. (b) Applicable cost principles. For each kind of organization, there is a...

  6. 29 CFR 1470.22 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... to that circular 48 CFR part 31. Contract Cost Principles and Procedures, or uniform cost accounting... Financial Administration § 1470.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used... grantee or subgrantee. (b) Applicable cost principles. For each kind of organization, there is a set of...

  7. 40 CFR 31.22 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... accounting standards that comply with cost principles acceptable to the Federal agency. ... Requirements Financial Administration § 31.22 Allowable costs. (a) Limitation on use of funds. Grant funds may... the grantee or sub-grantee. (b) Applicable cost principles. For each kind of organization, there is a...

  8. 34 CFR 80.22 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... CFR part 31. Contract Cost Principles and Procedures, or uniform cost accounting standards that comply... COOPERATIVE AGREEMENTS TO STATE AND LOCAL GOVERNMENTS Post-Award Requirements Financial Administration § 80.22... kind of organization, there is a set of Federal principles for determining allowable costs. For the...

  9. 45 CFR 92.22 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... to that circular 48 CFR Part 31. Contract Cost Principles and Procedures, or uniform cost accounting... Financial Administration § 92.22 Allowable costs. (a) Limitation on use of funds. Grant funds may be used... grantee or subgrantee. (b) Applicable cost principles. For each kind of organization, there is a set of...

  10. 7 CFR 3016.22 - Allowable costs.

    Science.gov (United States)

    2010-01-01

    ... uniform cost accounting standards that comply with cost principles acceptable to the Federal agency. ... Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF... GOVERNMENTS Post-Award Requirements Financial Administration § 3016.22 Allowable costs. (a) Limitation on use...

  11. 10 CFR 440.18 - Allowable expenditures.

    Science.gov (United States)

    2010-01-01

    ... part for labor, weatherization materials, and related matters for a renewable energy system, shall not... beginning in calendar year 2010 and the $3,000 average for renewable energy systems will be adjusted... 10 Energy 3 2010-01-01 2010-01-01 false Allowable expenditures. 440.18 Section 440.18 Energy...

  12. 42 CFR 417.534 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... typical “provider” costs, and costs (such as marketing, enrollment, membership, and operation of the HMO... principles applicable to provider costs, as set forth in § 417.536. (2) The allowability of other costs is determined in accordance with principles set forth in §§ 417.538 through 417.550. (3) Costs for covered...

  13. 44 CFR 295.21 - Allowable compensation.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Allowable compensation. 295.21 Section 295.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT... no-cost crisis counseling services available in the community. FEMA will not reimburse for treatment...

  14. 38 CFR 21.260 - Subsistence allowance.

    Science.gov (United States)

    2010-07-01

    ... rehabilitation facility or sheltered workshop; independent instructor; institutional non-farm cooperative: Full...) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under 38 U.S.C. Chapter 31... rehabilitation program under 38 U.S.C. Chapter 31 will receive a monthly subsistence allowance at the rates in...

  15. 43 CFR 12.62 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... uniform cost accounting standards that comply with cost principles acceptable to the Federal agency. ... COST PRINCIPLES FOR ASSISTANCE PROGRAMS Uniform Administrative Requirements for Grants and Cooperative... increment above allowable costs) to the grantee or subgrantee. (b) Applicable cost principles. For each kind...

  16. 45 CFR 74.27 - Allowable costs.

    Science.gov (United States)

    2010-10-01

    ... FOR AWARDS AND SUBAWARDS TO INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, OTHER NONPROFIT ORGANIZATIONS, AND COMMERCIAL ORGANIZATIONS Post-Award Requirements Financial and Program Management § 74.27... Organizations” and paragraph (b) of this section. The allowability of costs incurred by institutions of higher...

  17. 22 CFR 145.27 - Allowable costs.

    Science.gov (United States)

    2010-04-01

    ... Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 145...-Profit Organizations.” The allowability of costs incurred by institutions of higher education is...

  18. 22 CFR 518.27 - Allowable costs.

    Science.gov (United States)

    2010-04-01

    ... INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 518.27 Allowable costs. For each kind of recipient, there is a set of... by institutions of higher education is determined in accordance with the provisions of OMB Circular A...

  19. 33 CFR 136.217 - Compensation allowable.

    Science.gov (United States)

    2010-07-01

    ...) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF SOURCE; AND ADVERTISEMENT Procedures for Particular Claims § 136.217 Compensation... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Compensation allowable. 136.217...

  20. 33 CFR 136.205 - Compensation allowable.

    Science.gov (United States)

    2010-07-01

    ...) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF SOURCE; AND ADVERTISEMENT Procedures for Particular Claims § 136.205 Compensation... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Compensation allowable. 136.205...

  1. 20 CFR 632.37 - Allowable costs.

    Science.gov (United States)

    2010-04-01

    ... otherwise indicated below, direct and indirect costs shall be charged in accordance with 41 CFR 29-70 and 41... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Allowable costs. 632.37 Section 632.37 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN...

  2. First direct observation of bound-state beta-decay: Measurements of branching and lifetime of 207Tl81+ fragments

    International Nuclear Information System (INIS)

    Boutin, D.

    2005-08-01

    The first experimental observation of bound-state beta-decay showed, that due solely to the electron stripping, a stable nuclide, e.g. 163 Dy, became unstable. Also a drastic modification of the half-life of bare 187 Re, from 4.12(2) x 10 10 years down to 32.9(20) years, could be observed. It was mainly due to the possibility for the mother nuclide to decay into a previously inaccessible nuclear level of the daughter nuclide. It was proposed to study a nuclide where this decay mode was competing with continuum-state beta-decay, in order to measure their respective branchings. The ratio β b /β c could also be evaluated for the first time. 207 Tl was chosen due to its high atomic number, and Q-value of about 1.4 MeV, small enough to enhance the β b probability and large enough to allow the use of time-resolved Schottky Mass Spectrometry (SMS) to study the evolution of mother and bound-state beta-decay daughter ions. The decay properties of the ground state and isomeric state of 207 Tl 81+ have been investigated at the GSI accelerator facility in two separate experiments. For the first time β-decay where the electron could go either to a bound state (atomic orbitals) and lead to 207 Pb 81+ as a daughter nuclide, or to a continuum state and lead to 207 Pb 82+ , has been observed. The respective branchings of these two processes could be measured as well. The deduced total nuclear half-life of 255(17) s for 207 Tl 81+ , was slightly modified with respect to the half-life of the neutral atom of 286(2) s. It was nevertheless in very good agreement with calculations based on the assumption that the beta-decay was following an allowed type of transition. The branching β b /β c =0.192(20), was also in very good agreement with the same calculations. The application of stochastic precooling allowed to observe in addition the 1348 keV short-lived isomeric state of 207 Tl. The half-life of this isomeric state was measured as 1.47(32) s, which shows a small deviation

  3. Structural Phase Transition Nomenclature, Report of an IUCr Working Group on Phase Transition Nomenclature

    NARCIS (Netherlands)

    Toleddano, J.C.; Glazer, A.M.; Hahn, Th.; Parthe, E.; Roth, R.S.; Berry, R.S.; Metselaar, R.; Abrahams, S.C.

    1998-01-01

    A compact and intuitive nomenclature is recommended for naming each phase formed by a given material in a sequence of phase transitions as a function of temperature and/or pressure. The most commonly used label for each phase in a sequence, such as [alpha], [beta], ..., I, II, ... etc., is included

  4. 33 CFR 401.89 - Transit refused.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Transit refused. 401.89 Section... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations General § 401.89 Transit refused. (a) An officer may refuse to allow a vessel to transit when, (1) The vessel is not equipped in accordance with §§ 401.5 to...

  5. Smart Beta or Smart Alpha

    DEFF Research Database (Denmark)

    Winther, Kenneth Lillelund; Steenstrup, Søren Resen

    2016-01-01

    that smart beta investing probably will do better than passive market capitalization investing over time, we believe many are coming to a conclusion too quickly regarding active managers. Institutional investors are able to guide managers through benchmarks and risk frameworks toward the same well......Smart beta has become the flavor of the decade in the investment world with its low fees, easy access to rewarded risk premiums, and appearance of providing good investment results relative to both traditional passive benchmarks and actively managed funds. Although we consider it well documented......-documented smart beta risk premiums and still motivate active managers to avoid value traps, too highly priced small caps, defensives, etc. By constructing the equity portfolios of active managers that resemble the most widely used risk premiums, we show that the returns and risk-adjusted returns measures...

  6. Panel Smooth Transition Regression Models

    DEFF Research Database (Denmark)

    González, Andrés; Terasvirta, Timo; Dijk, Dick van

    We introduce the panel smooth transition regression model. This new model is intended for characterizing heterogeneous panels, allowing the regression coefficients to vary both across individuals and over time. Specifically, heterogeneity is allowed for by assuming that these coefficients are bou...

  7. Unified description of the softening behavior of beta-metastable and alpha+beta titanium alloys during hot deformation

    International Nuclear Information System (INIS)

    Poletti, Cecilia; Germain, Lionel; Warchomicka, Fernando; Dikovits, Martina; Mitsche, Stefan

    2016-01-01

    In this work, we propose a unified description of the softening behavior of a β metastable alloy and Ti6Al4V alloy. In the first part we provide sound evidence that the hot deformation of Ti6Al4V of the beta phase above and below the beta transus temperature takes place solely by dynamic recovery at moderate strains, similarly to the behavior of the Ti5Al5Mo5V3Cr1Zr near-beta alloy. This study was possible due to the combination of the fast cooling rates achieved after controlled hot deformation and the reconstruction of the parent beta phase from electron backscattered diffraction measurements of the frozen alpha phase by using an innovative developed algorithm. The dynamic recovery as a common dynamic restoration behavior for Ti6Al4V and Ti5Al5Mo5V3Cr1Zr is described mathematically with a Derby type relationship of the subgrain size and the stress of the beta phase. A rule of mixture allows the determination of the load partition between the two allotropic phases.

  8. Deconfinement and the Hagedorn transition in string theory.

    Science.gov (United States)

    Chaudhuri, S

    2001-03-05

    We introduce a new definition of the thermal partition function in string theory. With this new definition, the thermal partition functions of all of the string theories obey thermal duality relations with self-dual Hagedorn temperature beta(2)(H) = 4pi(2)alpha('). A beta-->beta(2)(H)/beta transformation maps the type I theory into a new string theory (type I) with thermal D p-branes, spatial hypersurfaces supporting a p-dimensional finite temperature non-Abelian Higgs-gauge theory for p< or =9. We demonstrate a continuous phase transition in the behavior of the static heavy quark-antiquark potential for small separations r(2)(*)transitioning through a precise inverse power law at a critical temperature T(D) = T(H)r(*)/(2alpha('))(1/2)pi.

  9. Beta decay of 22O

    International Nuclear Information System (INIS)

    Hubert, F.; Dufour, J.P.; Moral, R. del; Fleury, A.; Jean, D.; Pravikoff, M.S.; Delagrange, H.; Geissel, H.; Schmidt, K.H.; Hanelt, E.

    1989-01-01

    The beta-gamma spectroscopic study of 22 O is presented. This nucleus, produced as a projectile-like fragment from the interaction of a 60 MeV/n 40 Ar beam with a Be target, has been separated by the LISE spectrometer. Several gamma rays from 22 O decay have been observed, from which a half-life of (2.25±0.15) s has been determined. Accurate excitation energies have been deduced for several states in 22 F. A partial beta decay scheme of 22 O has been established. Experimental results have been compared with shell model calculations. (orig.)

  10. Beta-hemolytic Streptococcal Bacteremia

    DEFF Research Database (Denmark)

    Nielsen, Hans Ulrik; Kolmos, Hans Jørn; Frimodt-Møller, Niels

    2002-01-01

    Bacteremia with beta-hemolytic Streptococci groups A, B, C and G has a mortality rate of approximately 20%. In this study we analyzed the association of various patient risk factors with mortality. Records from 241 patients with beta-hemolytic streptococcal bacteremia were reviewed with particular...... attention to which predisposing factors were predictors of death. A logistic regression model found age, burns, immunosuppressive treatment and iatrogenic procedures prior to the infection to be significant predictors of death, with odds ratios of 1.7 (per decade), 19.7, 3.6 and 6.8, respectively...

  11. The Beta Transmuted Weibull Distribution

    Directory of Open Access Journals (Sweden)

    Manisha Pal

    2014-06-01

    Full Text Available The paper introduces a beta transmuted Weibull distribution, which contains a number ofdistributions as special cases. The properties of the distribution are discussed and explicit expressions are derived for the mean deviations, Bonferroni and Lorenz curves, and reliability. The distribution and moments of order statistics are also studied. Estimation of the model parameters by the method of maximum likelihood is discussed. The log beta transmuted Weibull model is introduced to analyze censored data. Finally, the usefulness of the new distribution in analyzing positive data is illustrated.

  12. Beta activity of enriched uranium

    International Nuclear Information System (INIS)

    Nambiar, P.P.V.J.; Ramachandran, V.

    1975-01-01

    Use of enriched uranium as reactor fuel necessitates its handling in various forms. For purposes of planning and organising radiation protection measures in enriched uranium handling facilities, it is necessary to have a basic knowledge of the radiation status of enriched uranium systems. The theoretical variations in beta activity and energy with U 235 enrichment are presented. Depletion is considered separately. Beta activity build up is also studied for two specific enrichments, in respect of which experimental values for specific alpha activity are available. (author)

  13. A {beta} - {gamma} coincidence; Metodo de coincidencias {beta} - {gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Agullo, F

    1960-07-01

    A {beta} - {gamma} coincidence method for absolute counting is given. The fundamental principles are revised and the experimental part is detailed. The results from {sup 1}98 Au irradiated in the JEN 1 Swimming pool reactor are given. The maximal accuracy is 1 per cent. (Author) 11 refs.

  14. Making It Personal: Per Capita Carbon Allowances

    DEFF Research Database (Denmark)

    Fawcett, Tina; Hvelplund, Frede; Meyer, Niels I

    2009-01-01

    The Chapter highligts the importance of introducing new, efficient schemes for mitigation of global warming. One such scheme is Personal Carbon Allowances (PCA), whereby individuals are allotted a tradable ration of CO2 emission per year.This chapter reviews the fundamentals of PCA and analyzes its...... merits and problems. The United Kingdom and Denmark have been chosen as case studies because the energy situation and the institutional setup are quite different between the two countries....

  15. N-Benzylhydroxylamine addition to beta-aryl enoates. Enantioselective synthesis of beta-aryl-beta-amino acid precursors

    Science.gov (United States)

    Sibi; Liu

    2000-10-19

    Chiral Lewis acid catalyzed N-benzylhydroxylamine addition to pyrrolidinone-derived enoates afforded beta-aryl-beta-amino acid derivatives in high enantiomeric purity with moderate to very good chemical efficiency.

  16. Army Leader Transitions Handbook

    Science.gov (United States)

    2008-01-01

    The courseware allows users to tailor training materials to specific needs. Users access this at the CAL AKO website or Army eLearning https...usarmy.skillport.com/ skillportfe/login/usarmylogin.cfm. New users must register with eLearning . Then login, select “Army Custom Curricula” and scroll to...challenges of your transition. Patience, flexibility and a good understanding of influence techniques on your part will help make any needed realignment a

  17. Phase transitions in the $sdg$ interacting boson model

    OpenAIRE

    Van Isacker, P.; Bouldjedri, A.; Zerguine, S.

    2009-01-01

    19 pages, 5 figures, submitted to Nuclear Physics A; A geometric analysis of the $sdg$ interacting boson model is performed. A coherent-state is used in terms of three types of deformation: axial quadrupole ($\\beta_2$), axial hexadecapole ($\\beta_4$) and triaxial ($\\gamma_2$). The phase-transitional structure is established for a schematic $sdg$ hamiltonian which is intermediate between four dynamical symmetries of U(15), namely the spherical ${\\rm U}(5)\\otimes{\\rm U}(9)$, the (prolate and ob...

  18. Determination of $\\gamma$ and $-2\\beta_s$ from charmless two-body decays of beauty mesons

    CERN Document Server

    Aaij, Roel; Adeva, Bernardo; Adinolfi, Marco; Affolder, Anthony; Ajaltouni, Ziad; Akar, Simon; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Anderson, Jonathan; Andreassen, Rolf; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Aquines Gutierrez, Osvaldo; Archilli, Flavio; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Auriemma, Giulio; Baalouch, Marouen; Bachmann, Sebastian; Back, John; Badalov, Alexey; Baesso, Clarissa; Baldini, Wander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Batozskaya, Varvara; Battista, Vincenzo; Bay, Aurelio; Beaucourt, Leo; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Belogurov, Sergey; Belous, Konstantin; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Benton, Jack; Berezhnoy, Alexander; Bernet, Roland; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bien, Alexander; Bifani, Simone; Bird, Thomas; Bizzeti, Andrea; Bjørnstad, Pål Marius; Blake, Thomas; Blanc, Frédéric; Blouw, Johan; Blusk, Steven; Bocci, Valerio; Bondar, Alexander; Bondar, Nikolay; Bonivento, Walter; Borghi, Silvia; Borgia, Alessandra; Borsato, Martino; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Brambach, Tobias; Bressieux, Joël; Brett, David; Britsch, Markward; Britton, Thomas; Brodzicka, Jolanta; Brook, Nicholas; Brown, Henry; Bursche, Albert; Busetto, Giovanni; Buytaert, Jan; Cadeddu, Sandro; Calabrese, Roberto; Calvi, Marta; Calvo Gomez, Miriam; Campana, Pierluigi; Campora Perez, Daniel; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casse, Gianluigi; Cassina, Lorenzo; Castillo Garcia, Lucia; Cattaneo, Marco; Cauet, Christophe; Cenci, Riccardo; Charles, Matthew; Charpentier, Philippe; Chefdeville, Maximilien; Chen, Shanzhen; Cheung, Shu-Faye; Chiapolini, Nicola; Chrzaszcz, Marcin; Ciba, Krzystof; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Cojocariu, Lucian; Collins, Paula; Comerma-Montells, Albert; Contu, Andrea; Cook, Andrew; Coombes, Matthew; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Counts, Ian; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Cruz Torres, Melissa Maria; Cunliffe, Samuel; Currie, Robert; D'Ambrosio, Carmelo; Dalseno, Jeremy; David, Pascal; David, Pieter; Davis, Adam; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Silva, Weeraddana; De Simone, Patrizia; Decamp, Daniel; Deckenhoff, Mirko; Del Buono, Luigi; Déléage, Nicolas; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Di Canto, Angelo; Dijkstra, Hans; Donleavy, Stephanie; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Dossett, David; Dovbnya, Anatoliy; Dreimanis, Karlis; Dujany, Giulio; Dupertuis, Frederic; Durante, Paolo; Dzhelyadin, Rustem; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; El Rifai, Ibrahim; Elsasser, Christian; Ely, Scott; Esen, Sevda; Evans, Hannah Mary; Evans, Timothy; Falabella, Antonio; Färber, Christian; Farinelli, Chiara; Farley, Nathanael; Farry, Stephen; Fay, Robert; Ferguson, Dianne; Fernandez Albor, Victor; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fiore, Marco; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fol, Philip; Fontana, Marianna; Fontanelli, Flavio; Forty, Roger; Francisco, Oscar; Frank, Markus; Frei, Christoph; Frosini, Maddalena; Fu, Jinlin; Furfaro, Emiliano; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; García Pardiñas, Julián; Garofoli, Justin; Garra Tico, Jordi; Garrido, Lluis; Gaspar, Clara; Gauld, Rhorry; Gavardi, Laura; Gavrilov, Gennadii; Geraci, Angelo; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianelle, Alessio; Gianì, Sebastiana; Gibson, Valerie; Giubega, Lavinia-Helena; Gligorov, Vladimir; Göbel, Carla; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gotti, Claudio; Grabalosa Gándara, Marc; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graziani, Giacomo; Grecu, Alexandru; Greening, Edward; Gregson, Sam; Griffith, Peter; Grillo, Lucia; Grünberg, Oliver; Gui, Bin; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hall, Samuel; Hamilton, Brian; Hampson, Thomas; Han, Xiaoxue; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Jonathan; He, Jibo; Head, Timothy; Heijne, Veerle; Hennessy, Karol; Henrard, Pierre; Henry, Louis; Hernando Morata, Jose Angel; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hoballah, Mostafa; Hombach, Christoph; Hulsbergen, Wouter; Hunt, Philip; Hussain, Nazim; Hutchcroft, David; Hynds, Daniel; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jaeger, Andreas; Jalocha, Pawel; Jans, Eddy; Jaton, Pierre; Jawahery, Abolhassan; Jing, Fanfan; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kaballo, Michael; Kandybei, Sergii; Kanso, Walaa; Karacson, Matthias; Karbach, Moritz; Karodia, Sarah; Kelsey, Matthew; Kenyon, Ian; Ketel, Tjeerd; Khanji, Basem; Khurewathanakul, Chitsanu; Klaver, Suzanne; Klimaszewski, Konrad; Kochebina, Olga; Kolpin, Michael; Komarov, Ilya; Koopman, Rose; Koppenburg, Patrick; Korolev, Mikhail; Kozlinskiy, Alexandr; Kravchuk, Leonid; Kreplin, Katharina; Kreps, Michal; Krocker, Georg; Krokovny, Pavel; Kruse, Florian; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kurek, Krzysztof; Kvaratskheliya, Tengiz; La Thi, Viet Nga; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lambert, Dean; Lambert, Robert W; Lanfranchi, Gaia; Langenbruch, Christoph; Langhans, Benedikt; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; van Leerdam, Jeroen; Lees, Jean-Pierre; Lefèvre, Regis; Leflat, Alexander; Lefrançois, Jacques; Leo, Sabato; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Yiming; Likhomanenko, Tatiana; Liles, Myfanwy; Lindner, Rolf; Linn, Christian; Lionetto, Federica; Liu, Bo; Lohn, Stefan; Longstaff, Iain; Lopes, Jose; Lopez-March, Neus; Lowdon, Peter; Lu, Haiting; Lucchesi, Donatella; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Machefert, Frederic; Machikhiliyan, Irina V; Maciuc, Florin; Maev, Oleg; Malde, Sneha; Malinin, Alexander; Manca, Giulia; Mancinelli, Giampiero; Mapelli, Alessandro; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marino, Pietro; Märki, Raphael; Marks, Jörg; Martellotti, Giuseppe; Martens, Aurelien; Martín Sánchez, Alexandra; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Martins Tostes, Danielle; Massafferri, André; Matev, Rosen; Mathe, Zoltan; Matteuzzi, Clara; Mazurov, Alexander; McCann, Michael; McCarthy, James; McNab, Andrew; McNulty, Ronan; McSkelly, Ben; Meadows, Brian; Meier, Frank; Meissner, Marco; Merk, Marcel; Milanes, Diego Alejandro; Minard, Marie-Noelle; Moggi, Niccolò; Molina Rodriguez, Josue; Monteil, Stephane; Morandin, Mauro; Morawski, Piotr; Mordà, Alessandro; Morello, Michael Joseph; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Müller, Katharina; Mussini, Manuel; Muster, Bastien; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Anh Duc; Nguyen, Thi-Dung; Nguyen-Mau, Chung; Nicol, Michelle; Niess, Valentin; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Novoselov, Alexey; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Oggero, Serena; Ogilvy, Stephen; Okhrimenko, Oleksandr; Oldeman, Rudolf; Onderwater, Gerco; Orlandea, Marius; Otalora Goicochea, Juan Martin; Owen, Patrick; Oyanguren, Maria Arantza; Pal, Bilas Kanti; Palano, Antimo; Palombo, Fernando; Palutan, Matteo; Panman, Jacob; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Parkes, Christopher; Parkinson, Christopher John; Passaleva, Giovanni; Patel, Girish; Patel, Mitesh; Patrignani, Claudia; Pazos Alvarez, Antonio; Pearce, Alex; Pellegrino, Antonio; Pepe Altarelli, Monica; Perazzini, Stefano; Perez Trigo, Eliseo; Perret, Pascal; Perrin-Terrin, Mathieu; Pescatore, Luca; Pesen, Erhan; Petridis, Konstantin; Petrolini, Alessandro; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pilař, Tomas; Pinci, Davide; Pistone, Alessandro; Playfer, Stephen; Plo Casasus, Maximo; Polci, Francesco; Poluektov, Anton; Polycarpo, Erica; Popov, Alexander; Popov, Dmitry; Popovici, Bogdan; Potterat, Cédric; Price, Eugenia; Price, Joseph David; Prisciandaro, Jessica; Pritchard, Adrian; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Punzi, Giovanni; Qian, Wenbin; Rachwal, Bartolomiej; Rademacker, Jonas; Rakotomiaramanana, Barinjaka; Rama, Matteo; Rangel, Murilo; Raniuk, Iurii; Rauschmayr, Nathalie; Raven, Gerhard; Redi, Federico; Reichert, Stefanie; Reid, Matthew; dos Reis, Alberto; Ricciardi, Stefania; Richards, Sophie; Rihl, Mariana; Rinnert, Kurt; Rives Molina, Vincente; Robbe, Patrick; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Perez, Pablo; Roiser, Stefan; Romanovsky, Vladimir; Romero Vidal, Antonio; Rotondo, Marcello; Rouvinet, Julien; Ruf, Thomas; Ruiz, Hugo; Ruiz Valls, Pablo; Saborido Silva, Juan Jose; Sagidova, Naylya; Sail, Paul; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santovetti, Emanuele; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saunders, Daniel Martin; Savrie, Mauro; Savrina, Darya; Schiller, Manuel; Schindler, Heinrich; Schlupp, Maximilian; Schmelling, Michael; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Seco, Marcos; Semennikov, Alexander; Sepp, Indrek; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shapoval, Illya; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Shires, Alexander; Silva Coutinho, Rafael; Simi, Gabriele; Sirendi, Marek; Skidmore, Nicola; Skwarnicki, Tomasz; Smith, Anthony; Smith, Edmund; Smith, Eluned; Smith, Jackson; Smith, Mark; Snoek, Hella; Sokoloff, Michael; Soler, Paul; Soomro, Fatima; Souza, Daniel; Souza De Paula, Bruno; Spaan, Bernhard; Sparkes, Ailsa; Spradlin, Patrick; Sridharan, Srikanth; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Steinkamp, Olaf; Stenyakin, Oleg; Stevenson, Scott; Stoica, Sabin; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Straticiuc, Mihai; Straumann, Ulrich; Stroili, Roberto; Subbiah, Vijay Kartik; Sun, Liang; Sutcliffe, William; Swientek, Krzysztof; Swientek, Stefan; Syropoulos, Vasileios; Szczekowski, Marek; Szczypka, Paul; Szilard, Daniela; Szumlak, Tomasz; T'Jampens, Stephane; Teklishyn, Maksym; Tellarini, Giulia; Teubert, Frederic; Thomas, Christopher; Thomas, Eric; van Tilburg, Jeroen; Tisserand, Vincent; Tobin, Mark; Tolk, Siim; Tomassetti, Luca; Topp-Joergensen, Stig; Torr, Nicholas; Tournefier, Edwige; Tourneur, Stephane; Tran, Minh Tâm; Tresch, Marco; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tuning, Niels; Ubeda Garcia, Mario; Ukleja, Artur; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagnoni, Vincenzo; Valenti, Giovanni; Vallier, Alexis; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vázquez Sierra, Carlos; Vecchi, Stefania; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Vesterinen, Mika; Viaud, Benoit; Vieira, Daniel; Vieites Diaz, Maria; Vilasis-Cardona, Xavier; Vollhardt, Achim; Volyanskyy, Dmytro; Voong, David; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; Voss, Helge; de Vries, Jacco; Waldi, Roland; Wallace, Charlotte; Wallace, Ronan; Walsh, John; Wandernoth, Sebastian; Wang, Jianchun; Ward, David; Watson, Nigel; Websdale, David; Whitehead, Mark; Wicht, Jean; Wiedner, Dirk; Wilkinson, Guy; Williams, Matthew; Williams, Mike; Wilschut, Hans; Wilson, Fergus; Wimberley, Jack; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wright, Simon; Wyllie, Kenneth; Xie, Yuehong; Xing, Zhou; Xu, Zhirui; Yang, Zhenwei; Yuan, Xuhao; Yushchenko, Oleg; Zangoli, Maria; Zavertyaev, Mikhail; Zhang, Liming; Zhang, Wen Chao; Zhang, Yanxi; Zhelezov, Alexey; Zhokhov, Anatoly; Zhong, Liang; Zvyagin, Alexander

    2015-01-01

    Using the latest LHCb measurements of time-dependent $C\\!P$ violation in the $B^0_s \\to K^+K^-$ decay, a U-spin relation between the decay amplitudes of $B^0_s \\to K^+K^-$ and $B^0\\to \\pi^+\\pi^-$ decay processes allows constraints to be placed on the angle $\\gamma$ of the unitarity triangle and on the $B^0_s$ mixing phase $-2\\beta_s$. Results from an extended approach, which uses additional inputs on $B^0\\to \\pi^0\\pi^0$ and $B^+\\to \\pi^+\\pi^0$ decays from other experiments and exploits isospin symmetry, are also presented. The dependence of the results on the maximum allowed amount of U-spin breaking is studied. At 68% probability, the value $\\gamma = \\left( 63.5^{\\,+\\, 7.2}_{\\,-\\,6.7} \\right)^\\circ~\\mathrm{modulo}~180^\\circ$ is determined. In an alternative analysis, the value $-2\\beta_s = -0.12 ^{\\,+\\,0.14}_{\\,-\\,0.16}\\,\\,\\mathrm{rad}$ is found. In both measurements, the uncertainties due to U-spin breaking effects up to 50% are included.

  19. Determination of $\\gamma$ and $-2\\beta_s$ from charmless two-body decays of beauty mesons

    CERN Document Server

    Aaij, Roel; Adeva, Bernardo; Adinolfi, Marco; Affolder, Anthony; Ajaltouni, Ziad; Akar, Simon; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Anderson, Jonathan; Andreassen, Rolf; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Aquines Gutierrez, Osvaldo; Archilli, Flavio; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Auriemma, Giulio; Baalouch, Marouen; Bachmann, Sebastian; Back, John; Badalov, Alexey; Baesso, Clarissa; Baldini, Wander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Batozskaya, Varvara; Battista, Vincenzo; Bay, Aurelio; Beaucourt, Leo; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Belogurov, Sergey; Belous, Konstantin; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Benton, Jack; Berezhnoy, Alexander; Bernet, Roland; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bien, Alexander; Bifani, Simone; Bird, Thomas; Bizzeti, Andrea; Bjørnstad, Pål Marius; Blake, Thomas; Blanc, Frédéric; Blouw, Johan; Blusk, Steven; Bocci, Valerio; Bondar, Alexander; Bondar, Nikolay; Bonivento, Walter; Borghi, Silvia; Borgia, Alessandra; Borsato, Martino; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Brambach, Tobias; Bressieux, Joël; Brett, David; Britsch, Markward; Britton, Thomas; Brodzicka, Jolanta; Brook, Nicholas; Brown, Henry; Bursche, Albert; Busetto, Giovanni; Buytaert, Jan; Cadeddu, Sandro; Calabrese, Roberto; Calvi, Marta; Calvo Gomez, Miriam; Campana, Pierluigi; Campora Perez, Daniel; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casse, Gianluigi; Cassina, Lorenzo; Castillo Garcia, Lucia; Cattaneo, Marco; Cauet, Christophe; Cenci, Riccardo; Charles, Matthew; Charpentier, Philippe; Chefdeville, Maximilien; Chen, Shanzhen; Cheung, Shu-Faye; Chiapolini, Nicola; Chrzaszcz, Marcin; Ciba, Krzystof; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Cojocariu, Lucian; Collins, Paula; Comerma-Montells, Albert; Contu, Andrea; Cook, Andrew; Coombes, Matthew; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Counts, Ian; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Cruz Torres, Melissa Maria; Cunliffe, Samuel; Currie, Robert; D'Ambrosio, Carmelo; Dalseno, Jeremy; David, Pascal; David, Pieter; Davis, Adam; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Silva, Weeraddana; De Simone, Patrizia; Decamp, Daniel; Deckenhoff, Mirko; Del Buono, Luigi; Déléage, Nicolas; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Di Canto, Angelo; Dijkstra, Hans; Donleavy, Stephanie; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Dossett, David; Dovbnya, Anatoliy; Dreimanis, Karlis; Dujany, Giulio; Dupertuis, Frederic; Durante, Paolo; Dzhelyadin, Rustem; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; El Rifai, Ibrahim; Elsasser, Christian; Ely, Scott; Esen, Sevda; Evans, Hannah Mary; Evans, Timothy; Falabella, Antonio; Färber, Christian; Farinelli, Chiara; Farley, Nathanael; Farry, Stephen; Fay, Robert; Ferguson, Dianne; Fernandez Albor, Victor; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fiore, Marco; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fol, Philip; Fontana, Marianna; Fontanelli, Flavio; Forty, Roger; Francisco, Oscar; Frank, Markus; Frei, Christoph; Frosini, Maddalena; Fu, Jinlin; Furfaro, Emiliano; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; García Pardiñas, Julián; Garofoli, Justin; Garra Tico, Jordi; Garrido, Lluis; Gaspar, Clara; Gauld, Rhorry; Gavardi, Laura; Gavrilov, Gennadii; Geraci, Angelo; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianelle, Alessio; Gianì, Sebastiana; Gibson, Valerie; Giubega, Lavinia-Helena; Gligorov, V.V.; Göbel, Carla; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gotti, Claudio; Grabalosa Gándara, Marc; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graziani, Giacomo; Grecu, Alexandru; Greening, Edward; Gregson, Sam; Griffith, Peter; Grillo, Lucia; Grünberg, Oliver; Gui, Bin; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hall, Samuel; Hamilton, Brian; Hampson, Thomas; Han, Xiaoxue; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Jonathan; He, Jibo; Head, Timothy; Heijne, Veerle; Hennessy, Karol; Henrard, Pierre; Henry, Louis; Hernando Morata, Jose Angel; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hoballah, Mostafa; Hombach, Christoph; Hulsbergen, Wouter; Hunt, Philip; Hussain, Nazim; Hutchcroft, David; Hynds, Daniel; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jaeger, Andreas; Jalocha, Pawel; Jans, Eddy; Jaton, Pierre; Jawahery, Abolhassan; Jing, Fanfan; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kaballo, Michael; Kandybei, Sergii; Kanso, Walaa; Karacson, Matthias; Karbach, Moritz; Karodia, Sarah; Kelsey, Matthew; Kenyon, Ian; Ketel, Tjeerd; Khanji, Basem; Khurewathanakul, Chitsanu; Klaver, Suzanne; Klimaszewski, Konrad; Kochebina, Olga; Kolpin, Michael; Komarov, Ilya; Koopman, Rose; Koppenburg, Patrick; Korolev, Mikhail; Kozlinskiy, Alexandr; Kravchuk, Leonid; Kreplin, Katharina; Kreps, Michal; Krocker, Georg; Krokovny, Pavel; Kruse, Florian; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kurek, Krzysztof; Kvaratskheliya, Tengiz; La Thi, Viet Nga; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lambert, Dean; Lambert, Robert W; Lanfranchi, Gaia; Langenbruch, Christoph; Langhans, Benedikt; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; van Leerdam, Jeroen; Lees, Jean-Pierre; Lefèvre, Regis; Leflat, Alexander; Lefrançois, Jacques; Leo, Sabato; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Yiming; Likhomanenko, Tatiana; Liles, Myfanwy; Lindner, Rolf; Linn, Christian; Lionetto, Federica; Liu, Bo; Lohn, Stefan; Longstaff, Iain; Lopes, Jose; Lopez-March, Neus; Lowdon, Peter; Lu, Haiting; Lucchesi, Donatella; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Machefert, Frederic; Machikhiliyan, Irina V; Maciuc, Florin; Maev, Oleg; Malde, Sneha; Malinin, Alexander; Manca, Giulia; Mancinelli, Giampiero; Mapelli, Alessandro; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marino, Pietro; Märki, Raphael; Marks, Jörg; Martellotti, Giuseppe; Martens, Aurelien; Martín Sánchez, Alexandra; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Martins Tostes, Danielle; Massafferri, André; Matev, Rosen; Mathe, Zoltan; Matteuzzi, Clara; Mazurov, Alexander; McCann, Michael; McCarthy, James; McNab, Andrew; McNulty, Ronan; McSkelly, Ben; Meadows, Brian; Meier, Frank; Meissner, Marco; Merk, Marcel; Milanes, Diego Alejandro; Minard, Marie-Noelle; Moggi, Niccolò; Molina Rodriguez, Josue; Monteil, Stephane; Morandin, Mauro; Morawski, Piotr; Mordà, Alessandro; Morello, Michael Joseph; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Müller, Katharina; Mussini, Manuel; Muster, Bastien; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Anh Duc; Nguyen, Thi-Dung; Nguyen-Mau, Chung; Nicol, Michelle; Niess, Valentin; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Novoselov, Alexey; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Oggero, Serena; Ogilvy, Stephen; Okhrimenko, Oleksandr; Oldeman, Rudolf; Onderwater, Gerco; Orlandea, Marius; Otalora Goicochea, Juan Martin; Owen, Patrick; Oyanguren, Maria Arantza; Pal, Bilas Kanti; Palano, Antimo; Palombo, Fernando; Palutan, Matteo; Panman, Jacob; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Parkes, Christopher; Parkinson, Christopher John; Passaleva, Giovanni; Patel, Girish; Patel, Mitesh; Patrignani, Claudia; Pazos Alvarez, Antonio; Pearce, Alex; Pellegrino, Antonio; Pepe Altarelli, Monica; Perazzini, Stefano; Perez Trigo, Eliseo; Perret, Pascal; Perrin-Terrin, Mathieu; Pescatore, Luca; Pesen, Erhan; Petridis, Konstantin; Petrolini, Alessandro; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pilař, Tomas; Pinci, Davide; Pistone, Alessandro; Playfer, Stephen; Plo Casasus, Maximo; Polci, Francesco; Poluektov, Anton; Polycarpo, Erica; Popov, Alexander; Popov, Dmitry; Popovici, Bogdan; Potterat, Cédric; Price, Eugenia; Price, Joseph David; Prisciandaro, Jessica; Pritchard, Adrian; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Punzi, Giovanni; Qian, Wenbin; Rachwal, Bartolomiej; Rademacker, Jonas; Rakotomiaramanana, Barinjaka; Rama, Matteo; Rangel, Murilo; Raniuk, Iurii; Rauschmayr, Nathalie; Raven, Gerhard; Redi, Federico; Reichert, Stefanie; Reid, Matthew; dos Reis, Alberto; Ricciardi, Stefania; Richards, Sophie; Rihl, Mariana; Rinnert, Kurt; Rives Molina, Vincente; Robbe, Patrick; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Perez, Pablo; Roiser, Stefan; Romanovsky, Vladimir; Romero Vidal, Antonio; Rotondo, Marcello; Rouvinet, Julien; Ruf, Thomas; Ruiz, Hugo; Ruiz Valls, Pablo; Saborido Silva, Juan Jose; Sagidova, Naylya; Sail, Paul; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santovetti, Emanuele; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saunders, Daniel Martin; Savrie, Mauro; Savrina, Darya; Schiller, Manuel; Schindler, Heinrich; Schlupp, Maximilian; Schmelling, Michael; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Seco, Marcos; Semennikov, Alexander; Sepp, Indrek; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shapoval, Illya; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Shires, Alexander; Silva Coutinho, Rafael; Simi, Gabriele; Sirendi, Marek; Skidmore, Nicola; Skwarnicki, Tomasz; Smith, Anthony; Smith, Edmund; Smith, Eluned; Smith, Jackson; Smith, Mark; Snoek, Hella; Sokoloff, Michael; Soler, Paul; Soomro, Fatima; Souza, Daniel; Souza De Paula, Bruno; Spaan, Bernhard; Sparkes, Ailsa; Spradlin, Patrick; Sridharan, Srikanth; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Steinkamp, Olaf; Stenyakin, Oleg; Stevenson, Scott; Stoica, Sabin; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Straticiuc, Mihai; Straumann, Ulrich; Stroili, Roberto; Subbiah, Vijay Kartik; Sun, Liang; Sutcliffe, William; Swientek, Krzysztof; Swientek, Stefan; Syropoulos, Vasileios; Szczekowski, Marek; Szczypka, Paul; Szilard, Daniela; Szumlak, Tomasz; T'Jampens, Stephane; Teklishyn, Maksym; Tellarini, Giulia; Teubert, Frederic; Thomas, Christopher; Thomas, Eric; van Tilburg, Jeroen; Tisserand, Vincent; Tobin, Mark; Tolk, Siim; Tomassetti, Luca; Topp-Joergensen, Stig; Torr, Nicholas; Tournefier, Edwige; Tourneur, Stephane; Tran, Minh Tâm; Tresch, Marco; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tuning, Niels; Ubeda Garcia, Mario; Ukleja, Artur; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagnoni, Vincenzo; Valenti, Giovanni; Vallier, Alexis; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vázquez Sierra, Carlos; Vecchi, Stefania; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Vesterinen, Mika; Viaud, Benoit; Vieira, Daniel; Vieites Diaz, Maria; Vilasis-Cardona, Xavier; Vollhardt, Achim; Volyanskyy, Dmytro; Voong, David; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; Voss, Helge; de Vries, Jacco; Waldi, Roland; Wallace, Charlotte; Wallace, Ronan; Walsh, John; Wandernoth, Sebastian; Wang, Jianchun; Ward, David; Watson, Nigel; Websdale, David; Whitehead, Mark; Wicht, Jean; Wiedner, Dirk; Wilkinson, Guy; Williams, Matthew; Williams, Mike; Wilschut, Hans; Wilson, Fergus; Wimberley, Jack; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wright, Simon; Wyllie, Kenneth; Xie, Yuehong; Xing, Zhou; Xu, Zhirui; Yang, Zhenwei; Yuan, Xuhao; Yushchenko, Oleg; Zangoli, Maria; Zavertyaev, Mikhail; Zhang, Liming; Zhang, Wen Chao; Zhang, Yanxi; Zhelezov, Alexey; Zhokhov, Anatoly; Zhong, Liang; Zvyagin, Alexander

    2015-02-04

    Using the latest LHCb measurements of time-dependent $C\\!P$ violation in the $B^0_s \\to K^+K^-$ decay, a U-spin relation between the decay amplitudes of $B^0_s \\to K^+K^-$ and $B^0\\to \\pi^+\\pi^-$ decay processes allows constraints to be placed on the angle $\\gamma$ of the unitarity triangle and on the $B^0_s$ mixing phase $-2\\beta_s$. Results from an extended approach, which uses additional inputs on $B^0\\to \\pi^0\\pi^0$ and $B^+\\to \\pi^+\\pi^0$ decays from other experiments and exploits isospin symmetry, are also presented. The dependence of the results on the maximum allowed amount of U-spin breaking is studied. At 68% probability, the value $\\gamma = \\left( 63.5^{\\,+\\, 7.2}_{\\,-\\,6.7} \\right)^\\circ~\\mathrm{modulo}~180^\\circ$ is determined. In an alternative analysis, the value $-2\\beta_s = -0.12 ^{\\,+\\,0.14}_{\\,-\\,0.16}\\,\\,\\mathrm{rad}$ is found. In both measurements, the uncertainties due to U-spin breaking effects up to 50% are included.

  20. $\\beta$-decay studies using total-absorption spectroscopy

    CERN Document Server

    Algora, A; García-Borge, M J; Cano-Ott, D; Collatz, R; Courtin, S; Dessagne, P; Fraile-Prieto, L M; Gadea, A; Gelletly, W; Hellström, M; Janas, Z; Jungclaus, A; Kirchner, R; Karny, M; Le Scornet, G; Miehé, C; Maréchal, F; Moroz, F; Nacher, E; Poirier, E; Roeckl, E; Rubio, B; Rykaczewski, K; Taín, J L; Tengblad, O; Wittmann, V

    2004-01-01

    $\\beta$-decay experiments are a primary source of information for nuclear-structure studies and at the same time complementary to in- beam investigations of nuclei far from stability. Although both types of experiment are mainly based on $\\gamma$-ray spectroscopy, they face different experimental problems. The so-called " Pandemonium effect " is a critical problem in $\\beta$-decay if we are to test theoretically calculated transition probabilities. In this contribution we will present a solution to this problem using total absorption spectroscopy methods. We will also present some examples of experiments carried out with the Total Absorption Spectrometer (TAS) at GSI and describe a new device LUCRECIA recently installed at CERN.

  1. Double beta decay and neutrino mass models

    Energy Technology Data Exchange (ETDEWEB)

    Helo, J.C. [Universidad Técnica Federico Santa María, Centro-Científico-Tecnológico de Valparaíso, Casilla 110-V, Valparaíso (Chile); Hirsch, M. [AHEP Group, Instituto de Física Corpuscular - C.S.I.C./Universitat de València, Edificio de Institutos de Paterna, Apartado 22085, E-46071 València (Spain); Ota, T. [Department of Physics, Saitama University, Shimo-Okubo 255, 338-8570 Saitama-Sakura (Japan); Santos, F.A. Pereira dos [Departamento de Física, Pontifícia Universidade Católica do Rio de Janeiro,Rua Marquês de São Vicente 225, 22451-900 Gávea, Rio de Janeiro (Brazil)

    2015-05-19

    Neutrinoless double beta decay allows to constrain lepton number violating extensions of the standard model. If neutrinos are Majorana particles, the mass mechanism will always contribute to the decay rate, however, it is not a priori guaranteed to be the dominant contribution in all models. Here, we discuss whether the mass mechanism dominates or not from the theory point of view. We classify all possible (scalar-mediated) short-range contributions to the decay rate according to the loop level, at which the corresponding models will generate Majorana neutrino masses, and discuss the expected relative size of the different contributions to the decay rate in each class. Our discussion is general for models based on the SM group but does not cover models with an extended gauge. We also work out the phenomenology of one concrete 2-loop model in which both, mass mechanism and short-range diagram, might lead to competitive contributions, in some detail.

  2. Alpha–beta monitoring system based on pair of simultaneous Multi-Wire Proportional Counters

    Energy Technology Data Exchange (ETDEWEB)

    Wengrowicz, U.; Amidan, D. [Department of Nuclear Engineering, Ben Gurion University of the Negev, Beer-Sheva 84105 (Israel); NRC-Negev, P.O. Box 9001, Beer-Sheva 84190 (Israel); Orion, I. [Department of Nuclear Engineering, Ben Gurion University of the Negev, Beer-Sheva 84105 (Israel)

    2016-08-11

    A new approach for a simultaneous alpha–beta Multi-wire Proportional Counter (MWPC) is presented. The popular approach for alpha–beta monitoring systems consists of a large area MWPC using noble gas flow such as Argon Methane. This method of measurement is effective but requires large-scale and expensive maintenance due to the needs of gas flow control and periodic replacements. In this work, a pair of simultaneous MWPCs for alpha–beta measuring is presented. The developed detector consists of a sealed gas MWPC sensor for beta particles, behind a free air alpha sensor. This approach allows effective simultaneous detection and discrimination of both alpha and beta radiation without the maintenance cost noble gas flow required for unsealed detectors.

  3. Electret dosemeter for beta radiation

    International Nuclear Information System (INIS)

    Campos, L.L.; Caldas, L.V.E.; Mascarenhas, S.

    The response characteristics of an electret dosemeter for beta radiation are studied. Experiments were performed using different geometries and walls, and it was verified for which geometry the dosemeter sensitivity is greater. Sources of 90 Sr - 90 Y, 204 Tl and 85 Kr were used in the experiments. (I.C.R.) [pt

  4. Personnel monitoring for beta rays

    International Nuclear Information System (INIS)

    Piesch, E.; Johns, T.F.

    1983-01-01

    The practical considerations which have to be taken into account in the design of personnel monitors intended to measure doses resulting from exposure to beta rays are discussed. These include the measurement of doses in situations involving either fairly uniform or non-uniform irradiation and of doses to the male gonads. (UK)

  5. Constraining neutrinoless double beta decay

    International Nuclear Information System (INIS)

    Dorame, L.; Meloni, D.; Morisi, S.; Peinado, E.; Valle, J.W.F.

    2012-01-01

    A class of discrete flavor-symmetry-based models predicts constrained neutrino mass matrix schemes that lead to specific neutrino mass sum-rules (MSR). We show how these theories may constrain the absolute scale of neutrino mass, leading in most of the cases to a lower bound on the neutrinoless double beta decay effective amplitude.

  6. Beta Cell Workshop 2013 Kyoto

    DEFF Research Database (Denmark)

    Heller, R Scott; Madsen, Ole D; Nielsen, Jens Høiriis

    2013-01-01

    The very modern Kyoto International Conference Center provided the site for the 8th workshop on Beta cells on April 23-26, 2013. The preceding workshops were held in Boston, USA (1991); Kyoto, Japan (1994); Helsingør, Denmark (1997); Helsinki, Finland (2003); El Perello, Spain (2006); Peebles...

  7. Sulfur dioxide allowances. Trading and technological progress

    International Nuclear Information System (INIS)

    Kumar, Surender; Managi, Shunsuke

    2010-01-01

    The US Clean Air Act Amendments introduce an emissions trading system to regulate SO 2 emissions. This study finds that changes in SO 2 emissions prices are related to innovations induced by these amendments. We find that electricity-generating plants are able to increase electricity output and reduce emissions of SO 2 and NO x from 1995 to 2007 due to the introduction of the allowance trading system. However, compared to the approximate 8% per year of exogenous technological progress, the induced effect is relatively small, and the contribution of the induced effect to overall technological progress is about 1-2%. (author)

  8. Beta calibration and dosimetry at IPEN

    International Nuclear Information System (INIS)

    Caldas, L.V.E.

    1983-01-01

    A commercial extrapolation chamber (PTW, Germany) was tested in different beta radiation fields and its properties investigated. Its usefullness for beta radiation calibration and dosimetry was demonstrated. (Author) [pt

  9. What parents say about the allowance: Function of the allowance for parents of different economic incomes

    Directory of Open Access Journals (Sweden)

    Irani Lauer Lellis

    2012-06-01

    Full Text Available The practice of giving allowance is used by several parents in different parts of the world and can contribute to the economic education of children. This study aimed to investigate the purposes of the allowance with 32 parents of varying incomes. We used the focus group technique and Alceste software to analyze the data. The results involved two classes related to the process of using the allowance. These classes have covered aspects of the role of socialization and education allowance, serving as an instrument of reward, but sometimes encouraging bad habits in children. The justification of the fathers concerning the amount of money to be given to the children and when to stop giving allowance were also highlighted.   Keywords: allowance; economic socialization; parenting practices.

  10. The Magnetically-Tuned Transition-Edge Sensor

    Science.gov (United States)

    Sadleir, John E.; Lee, Sang-Jun; Smith, Stephen J.; Busch, Sarah E.; Bandler, Simon R.; Adams, Joseph S.; Eckart, Megan E.; Chevenak, James A.; Kelley, Richard L.; Kilbourne, Caroline A.; hide

    2014-01-01

    We present the first measurements on the proposed magnetically-tuned superconducting transition-edge sensor (MTES) and compare the modified resistive transition with the theoretical prediction. A TES's resistive transition is customarily characterized in terms of the unit less device parameters alpha and beta corresponding to the resistive response to changes in temperature and current respectively. We present a new relationship between measured IV quantities and the parameters alpha and beta and use these relations to confirm we have stably biased a TES with negative beta parameter with magnetic tuning. Motivated by access to this new unexplored parameter space, we investigate the conditions for bias stability of a TES taking into account both self and externally applied magnetic fields.

  11. Shear induced phase transitions induced in edible fats

    Science.gov (United States)

    Mazzanti, Gianfranco; Welch, Sarah E.; Marangoni, Alejandro G.; Sirota, Eric B.; Idziak, Stefan H. J.

    2003-03-01

    The food industry crystallizes fats under different conditions of temperature and shear to obtain products with desired crystalline phases. Milk fat, palm oil, cocoa butter and chocolate were crystallized from the melt in a temperature controlled Couette cell. Synchrotron x-ray diffraction studies were conducted to examine the role of shear on the phase transitions seen in edible fats. The shear forces on the crystals induced acceleration of the alpha to beta-prime phase transition with increasing shear rate in milk fat and palm oil. The increase was slow at low shear rates and became very strong above 360 s-1. In cocoa butter the acceleration between beta-prime-III and beta-V phase transition increased until a maximum of at 360 s-1, and then decreased, showing competition between enhanced heat transfer and viscous heat generation.

  12. $\\beta$ - decay asymmetry in mirror nuclei: A = 9

    CERN Multimedia

    Axelsson, L E; Smedberg, M

    2002-01-01

    Investigations of light nuclei close to the drip lines have revealed new and intriguing features of the nuclear structure. The occurrence of halo structures in loosely bound systems has had a great impact on the nuclear physics research in the last years. As intriguing but not yet solved is the nature of transitions with very large $\\beta$ - strength. \\\\ \\\\We report here on the investigation of this latter feature by an accurate measurement of the $\\beta$ - decay asymmetry between the mirror nuclei in the A=9 mass chain.\\\\ \\\\The possible asymmetry for the decay to the states around 12 MeV is interesting not only due to the fact that the individual B$_{GT}$ values are large (with large overlap in wave-functions, an unambiguous interpretation is much easier made), but also due to the special role played by this transition for the $^{9}$Li decay. It seems to belong to a class of high-B$_{GT}$ transitions observed at the neutron drip line and has been suggested to be due either to a lowering of the giant Gamow-Te...

  13. Studies of $\\beta$-delayed two-proton emission : The cases of $^{31}$Ar and $^{35}$Ca

    CERN Multimedia

    Riisager, K; Jokinen, A; Canchel, G; Heinz, A M; Jonson, B N G; Dominguez reyes, R R; Koldste, G T; Fraile prieto, L M; Nilsson, T; Audirac, L L

    2008-01-01

    We propose to perform detailed studies of the decays of the two dripline nuclei $^{31}$Ar and $^{35}$Ca. This will allow an in-depth study in the process of $\\beta$-delayed two-proton emission ($\\beta$2p); as well as provide important information on resonances in $^{30}$S and $^{34}$Ar relevant for the astrophysical rp-process.

  14. A standardized method for in vivo mouse pancreas imaging and semiquantitative beta cell mass measurement by dual isotope SPECT

    NARCIS (Netherlands)

    Mathijs, I.; Xavier, C.; Peleman, C.; Caveliers, V.; Brom, M.; Gotthardt, M.; Herrera, P.L.; Lahoutte, T.; Bouwens, L.

    2015-01-01

    PURPOSE: In order to evaluate future beta cell tracers in vivo, we aimed to develop a standardized in vivo method allowing semiquantitative measurement of a prospective beta cell tracer within the pancreas. PROCEDURES: 2-[(123)I]Iodo-L-phenylalanine ([(123)I]IPA) and

  15. $\\beta$3$p$-spectroscopy and proton-$\\gamma$ width determination in the decay of $^{31}$Ar

    CERN Multimedia

    We propose to perform a detailed study of the $\\beta$-decay of the dripline nucleus $^{31}$Ar. This will allow a detailed study of the $\\beta$-delayed 3$p$-decay as well as provide important information on the resonances of $^{30}$S and $^{29}$P, in particular the ratio between the $p$- and $\\gamma$- partial widths relevant for astrophysics.

  16. Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis

    DEFF Research Database (Denmark)

    Aszodi, Attila; Hunziker, Ernst B; Brakebusch, Cord

    2003-01-01

    Beta1 integrins are highly expressed on chondrocytes, where they mediate adhesion to cartilage matrix proteins. To assess the functions of beta1 integrin during skeletogenesis, we inactivated the beta1 integrin gene in chondrocytes. We show here that these mutant mice develop a chondrodysplasia...... of various severity. beta1-deficient chondrocytes had an abnormal shape and failed to arrange into columns in the growth plate. This is caused by a lack of motility, which is in turn caused by a loss of adhesion to collagen type II, reduced binding to and impaired spreading on fibronectin, and an abnormal F......-actin organization. In addition, mutant chondrocytes show decreased proliferation caused by a defect in G1/S transition and cytokinesis. The G1/S defect is, at least partially, caused by overexpression of Fgfr3, nuclear translocation of Stat1/Stat5a, and up-regulation of the cell cycle inhibitors p16 and p21...

  17. Beta 3 and PDI proteins isolated from human platelets bind with ECwt rotavirus in vitro

    International Nuclear Information System (INIS)

    Mayorga, Diana; Rubio, Linda; Guerrero-Fonseca, Carlos A; Acosta-Losada, Orlando

    2010-01-01

    Commercial integrin Beta 3 is currently not available and commercial PDI is too expensive, which is making access difficult to these proteins needed for conducting experiments aimed at the establishment of possible interactions between integrin Beta 3 and PDI and wild type rotavirus strains. Objective. To explore a methodology allowing isolation of proteins Beta 3 and PDI from human platelets to be used as antigens in the generation of rabbit polyclonal antibodies useful in the assessment of interactions between these proteins and rotavirus ECwt. Materials and methods. Proteins Beta 3 and PDI from human platelet lysates were separated using preparative electrophoresis under reducing conditions and then eluted. Interactions of these proteins with rotavirus ECwt were analyzed using co-immunoprecipitation, Western blotting and capture ELISA. Results. Proteins from human platelet lysates were separated by preparative electrophoresis under reducing conditions. The identification of proteins Beta 3 and PDI present in a gel slice was performed through their reaction with commercial antibodies in a Western blotting analysis. Protein purity was established after electro elution from a gel slice. Polyclonal antibodies against protein Beta 3 were generated in rabbit. Incubation of eluted proteins Beta 3 and PDI with rotavirus ECwt showed in co-immunoprecipitation and ELISA assays that these proteins bound virus in vitro. The same binding was showed to occur when rotavirus was incubated with isolated small intestinal villi from suckling mice. Conclusions. Relatively high amounts of proteins Beta 3 and PDI were partially purified from human platelets by preparative electrophoresis. The isolation of these proteins allowed the generation of polyclonal antibodies against Beta 3 in addition to the establishment of the in vitro interaction of proteins Beta 3 and PDI with rotavirus ECwt. This interaction was also demonstrated in vivo after incubating the virus with isolated small

  18. Double beta decay and majorana neutrinos. Right-handed currents or nonzero masses

    International Nuclear Information System (INIS)

    Rosen, S.P.; Perlmutter, A.

    1981-01-01

    This chapter describes some new developments concerning the mechanism for lepton number nonconservation in no-neutrino double beta decay. Explains that lepton number nonconservation in no-neutrino double beta decay comes about either because both left- and right-handed components of a Majorano neutrino are coupled to the electron in the weak leptonic current, or because the neutrino has nonzero mass. Shows that while nuclear ground-state to ground-state transitions arise from right-handed currents and from neutrino mass terms, transitions to low-lying excited states with J /SUP P/ =2 + can arise only from right-handed currents. Emphasizes that the possibilities of detecting small admixtures of right-handed currents, and of setting limits on neutrino masses that are either very small or very large, make double beta decay a most rewarding phenomenon to study

  19. The use of (125I) iodocyanopindolol as a specific probe for beta-adrenergic receptors in differentiating cultured rat skeletal muscle

    International Nuclear Information System (INIS)

    Schonberg, Michael; Morris, S.A.; Krichevsky, Alexander; Bilezikian, J.P.

    1983-01-01

    In order to examine more precisely the role of beta-adrenergic receptors in the process of differentiation the new radioligand iodocyanopindolol was used, and found to be a very useful probe to identify beta receptors. Binding charcteristics conformed to those expected for a physiologically relevant beta receptor. L 6 E 9 cells grown in horse serum, which allows differentiation exhibit increased beta receptor density in intact cells as a function of age. In contrast, cells grown in fetal calf serum, which does not allow differentiation, exhibit constant beta receptor density. In broken cells, however, both differentiating and non-differentiating cells show an increase in beta receptors. These results suggest that the process of differentiation is associated with an unmasking of beta receptors which are increasing but cryptic in undifferentiated cells. (author)

  20. On Fuzzy {beta}-I-open sets and Fuzzy {beta}-I-continuous functions

    Energy Technology Data Exchange (ETDEWEB)

    Keskin, Aynur [Department of Mathematics, Faculty of Science and Arts, Selcuk University, Campus, 42075 Konya (Turkey)], E-mail: akeskin@selcuk.edu.tr

    2009-11-15

    In this paper, first of all we obtain some properties and characterizations of fuzzy {beta}-I-open sets. After that, we also define the notion of {beta}-I-closed sets and obtain some properties. Lastly, we introduce the notions of fuzzy {beta}-I-continuity with the help of fuzzy {beta}-I-open sets to obtain decomposition of fuzzy continuity.

  1. Beta-Catenin Stability in Breast Cancer

    National Research Council Canada - National Science Library

    Baswaran, Vijay

    1999-01-01

    .... beta-catenin also binds the adenomatous polyposis coli protein (APC). The tumor suppressor function of APC is suggested to depend in part on its ability to bind beta-catenin and to facilitate beta-catenin degradation by an unknown mechanism...

  2. Beta-lactamases in Enterobacteriaceae in broilers

    NARCIS (Netherlands)

    Dierikx, C.M.

    2013-01-01

    Resistance to cephalosprins due to the production of extended spectrum beta-lactamases (ESBLs) or plasmid mediated AmpC beta-lactamases is increasingly found in infections in humans outside the hospital. The genes encoding for these beta-lactamases are located on mobile DNA (plasmids), which can be

  3. Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro.

    Directory of Open Access Journals (Sweden)

    Holger A Russ

    Full Text Available Expansion of beta cells from the limited number of adult human islet donors is an attractive prospect for increasing cell availability for cell therapy of diabetes. However, attempts at expanding human islet cells in tissue culture result in loss of beta-cell phenotype. Using a lineage-tracing approach we provided evidence for massive proliferation of beta-cell-derived (BCD cells within these cultures. Expansion involves dedifferentiation resembling epithelial-mesenchymal transition (EMT. Epigenetic analyses indicate that key beta-cell genes maintain open chromatin structure in expanded BCD cells, although they are not transcribed. Here we investigated whether BCD cells can be redifferentiated into beta-like cells.Redifferentiation conditions were screened by following activation of an insulin-DsRed2 reporter gene. Redifferentiated cells were characterized for gene expression, insulin content and secretion assays, and presence of secretory vesicles by electron microscopy. BCD cells were induced to redifferentiate by a combination of soluble factors. The redifferentiated cells expressed beta-cell genes, stored insulin in typical secretory vesicles, and released it in response to glucose. The redifferentiation process involved mesenchymal-epithelial transition, as judged by changes in gene expression. Moreover, inhibition of the EMT effector SLUG (SNAI2 using shRNA resulted in stimulation of redifferentiation. Lineage-traced cells also gave rise at a low rate to cells expressing other islet hormones, suggesting transition of BCD cells through an islet progenitor-like stage during redifferentiation.These findings demonstrate for the first time that expanded dedifferentiated beta cells can be induced to redifferentiate in culture. The findings suggest that ex-vivo expansion of adult human islet cells is a promising approach for generation of insulin-producing cells for transplantation, as well as basic research, toxicology studies, and drug

  4. Beta dosimetry using pulsed laser heating of TLD materials

    International Nuclear Information System (INIS)

    Quam, W.

    1983-01-01

    Use of a pulsed CO 2 laser to heat the surface of hot-pressed LiF chips has been investigated. The thermoluminescent traps in the first 10 to 20 μm of depth may be read out with good efficiency, which will allow entrance dose and exit dose to be determined using a standard chip. These dose data can be used to calculate beta dose and gamma dose separately. Readout speed is estimated to be a few milliseconds per chip

  5. Pressure effect on the electrical conductivity and superconductivity of beta-(BDA-TTP)2I3.

    Science.gov (United States)

    Yamada, Jun-Ichi; Fujimoto, Kazuya; Akutsu, Hiroki; Nakatsuji, Shin'ichi; Miyazaki, Akira; Aimatsu, Masashi; Kudo, Satoshi; Enoki, Toshiaki; Kikuchi, Koichi

    2006-03-28

    The pressure-induced electrical conductivity properties of beta-(BDA-TTP)2I3 have been investigated; the salt exhibits a dramatic change in the conductivity behaviour above ca. 10 kbar and undergoes a superconducting transition with an onset near 10 K.

  6. ALPHA-BETA SEPARATION PORTFOLIO STRATEGIES FOR ISLAMIC FINANCE

    Directory of Open Access Journals (Sweden)

    Valentyn Khokhlov

    2016-11-01

    Full Text Available The purpose of this paper is to develop a mathematical alpha-beta separation model that can be used to create a core-satellite portfolio management strategy that complies with the principles of Islamic finance. Methodology. Core-satellite portfolio construction methodology is used to implement the alpha-beta separation approach, where the core part of the portfolio is managed using the tracking error minimization strategy, and the satellite part of the portfolio is managed using the mean-variance optimization strategy. Results of the portfolio dynamics clearly show that a significant amount of value was created by alpha-beta separation. The typical alpha ranges from 4% to 5.7%. The most aggressive portfolio strategies that allow short positions in the satellite portfolio work best with frequent rebalancing and benefit from the active bets. Smoothing technique that was introduced to decrease the portfolio turnover and stabilize its composition works better when active bets are less efficient, particularly with less frequent rebalancing. The best risk-return combinations are achieved with modest (3% to 10% allocation of the total portfolio to the satellite, and the remaining part (90% to 97% being managed in order to minimize the tracking error. Practical implications. The alpha-beta separation framework suggested in this paper can be used to enhance the portfolio management techniques for the hedge funds that operate under tight restrictions, particularly under the Islamic finance principles. The mathematical models developed in this paper allow practical implementation of the alphabeta separation concept. Originality/value. While the idea of alpha-beta separation existed in hedge fund management before, there was no comprehensive mathematical model under it, so its implementation was based on the ad hoc approach. This paper introduces such a mathematical model and demonstrates how portfolio managers can create value for their clients using it.

  7. 34 CFR 656.30 - What are allowable costs and limitations on allowable costs?

    Science.gov (United States)

    2010-07-01

    ... FOREIGN LANGUAGE AND AREA STUDIES OR FOREIGN LANGUAGE AND INTERNATIONAL STUDIES What Conditions Must Be... 34 Education 3 2010-07-01 2010-07-01 false What are allowable costs and limitations on allowable costs? 656.30 Section 656.30 Education Regulations of the Offices of the Department of Education...

  8. 40 CFR 82.8 - Grant of essential use allowances and critical use allowances.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Grant of essential use allowances and critical use allowances. 82.8 Section 82.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Albemarle Bill Clark Pest Control, Inc. Burnside Services, Inc. Cardinal Professional Products Chemtura Corp...

  9. 75 FR 14442 - Federal Travel Regulation (FTR); Relocation Allowances-Relocation Income Tax Allowance (RITA) Tables

    Science.gov (United States)

    2010-03-25

    ... GENERAL SERVICES ADMINISTRATION [GSA Bulletin FTR 10-04] Federal Travel Regulation (FTR); Relocation Allowances-- Relocation Income Tax Allowance (RITA) Tables AGENCY: Office of Governmentwide Policy... (73 FR 35952) specifying that GSA would no longer publish the RITA tables found in 41 CFR Part 301-17...

  10. 76 FR 32340 - Federal Travel Regulation; Temporary Duty (TDY) Travel Allowances (Taxes); Relocation Allowances...

    Science.gov (United States)

    2011-06-06

    ... reflection of the actual tax impact on the employee. Therefore, this proposed rule offers the one-year RITA... to estimate the additional income tax liability that you incur as a result of relocation benefits and... Allowances (Taxes); Relocation Allowances (Taxes) AGENCY: Office of Governmentwide Policy (OGP), General...

  11. The NUMEN project: NUclear Matrix Elements for Neutrinoless double beta decay

    Science.gov (United States)

    Cappuzzello, F.; Agodi, C.; Cavallaro, M.; Carbone, D.; Tudisco, S.; Lo Presti, D.; Oliveira, J. R. B.; Finocchiaro, P.; Colonna, M.; Rifuggiato, D.; Calabretta, L.; Calvo, D.; Pandola, L.; Acosta, L.; Auerbach, N.; Bellone, J.; Bijker, R.; Bonanno, D.; Bongiovanni, D.; Borello-Lewin, T.; Boztosun, I.; Brunasso, O.; Burrello, S.; Calabrese, S.; Calanna, A.; Chávez Lomelí, E. R.; D'Agostino, G.; De Faria, P. N.; De Geronimo, G.; Delaunay, F.; Deshmukh, N.; Ferreira, J. L.; Fisichella, M.; Foti, A.; Gallo, G.; Garcia-Tecocoatzi, H.; Greco, V.; Hacisalihoglu, A.; Iazzi, F.; Introzzi, R.; Lanzalone, G.; Lay, J. A.; La Via, F.; Lenske, H.; Linares, R.; Litrico, G.; Longhitano, F.; Lubian, J.; Medina, N. H.; Mendes, D. R.; Moralles, M.; Muoio, A.; Pakou, A.; Petrascu, H.; Pinna, F.; Reito, S.; Russo, A. D.; Russo, G.; Santagati, G.; Santopinto, E.; Santos, R. B. B.; Sgouros, O.; da Silveira, M. A. G.; Solakci, S. O.; Souliotis, G.; Soukeras, V.; Spatafora, A.; Torresi, D.; Magana Vsevolodovna, R.; Yildirim, A.; Zagatto, V. A. B.

    2018-05-01

    The article describes the main achievements of the NUMEN project together with an updated and detailed overview of the related R&D activities and theoretical developments. NUMEN proposes an innovative technique to access the nuclear matrix elements entering the expression of the lifetime of the double beta decay by cross section measurements of heavy-ion induced Double Charge Exchange (DCE) reactions. Despite the fact that the two processes, namely neutrinoless double beta decay and DCE reactions, are triggered by the weak and strong interaction respectively, important analogies are suggested. The basic point is the coincidence of the initial and final state many-body wave functions in the two types of processes and the formal similarity of the transition operators. First experimental results obtained at the INFN-LNS laboratory for the 40Ca(18O,18Ne)40Ar reaction at 270MeV give an encouraging indication on the capability of the proposed technique to access relevant quantitative information. The main experimental tools for this project are the K800 Superconducting Cyclotron and MAGNEX spectrometer. The former is used for the acceleration of the required high resolution and low emittance heavy-ion beams and the latter is the large acceptance magnetic spectrometer for the detection of the ejectiles. The use of the high-order trajectory reconstruction technique, implemented in MAGNEX, allows to reach the experimental resolution and sensitivity required for the accurate measurement of the DCE cross sections at forward angles. However, the tiny values of such cross sections and the resolution requirements demand beam intensities much larger than those manageable with the present facility. The on-going upgrade of the INFN-LNS facilities in this perspective is part of the NUMEN project and will be discussed in the article.

  12. Modification of beta dose evaluation algorithm for better accuracy in personnel monitoring

    International Nuclear Information System (INIS)

    Rakesh, R.B.; Kumar, Munish; Sneha, C.; Ratna, P.; Datta, D.

    2016-01-01

    Dose due to beta radiations is the main contributor to the skin dose. Assessment of individual dose (whole body, skin, extremity) in India is based on CaSO 4 :Dy based Teflon embedded TLD badge used for personnel monitoring. The design of the dosemeter enables identification of radiation type which, in turn, allows use of radiation specific algorithm for dose evaluation. The difference of response of three discs of the TLD badge to beta radiation in beta/beta-gamma fields is due to the presence of different filters corresponding to the three discs. The response of disc under metal filter (D 1 ) to beta being negligible while that of open disc (D 3 ) is the maximum. The ratio of response of open disc to that under Perspex (D 3 /D 2 ) to beta is highly dependent on its energy and angle of incidence. Therefore estimation of dose due to beta is based on response of open disc corrected for the energy of beta using D 3 /D 2

  13. Development and applications of beta and near beta titanium alloys

    International Nuclear Information System (INIS)

    Takemura, A.; Ohyama, H.; Nishimura, T.; Abumiya, T.

    1993-01-01

    In this report the authors introduced application of beta and near beta titanium alloys also development and processing of these alloys at Kobe Steel LTD. Ti-15Mo-5Zr-3Al is an alloy developed by Kobe Steel which has been applied for variety of sporting goods, also used as an erosion shield of steam turbine blades. Ti-15Mo-5Zr-3Al high strength wire for valve springs is under development. New beta alloys(Ti-V-Nb-Sn-Al) are under development which have lower flow stress at room temperature than Ti 15V-3Cr-3Sn-3Al, expected to improve productivity of cold forging. NNS forging and thermo mechanical treatment of Ti-10V-2Fe-3Al were studied. Ti-10V-2Fe3Al steam turbine blades and structural parts for aircraft were developed. Fine grain cold strips of Ti 15V-3Cr-3Sn-3Al are produced by annealing and pickling process. These cold strips are used for parts of a fishing rod

  14. Non-Transitive Consumer Behavior

    OpenAIRE

    Fuchs-Seliger, Susanne

    2006-01-01

    Rational choice when preferences are not required to be transitive and complete has been discussed in the literature for years. In this article transitivity and completeness of the preference relation is also not assumed. It will be shown that nevertheless the existence of a competitive equilibrium can be proven when those properties are replaced by a domination property which allows that there could be cicles among those alternatives which are of less importance for the individual and which ...

  15. PGC-1alpha and PGC-1beta have both similar and distinct effects on myofiber switching toward an oxidative phenotype

    DEFF Research Database (Denmark)

    Mortensen, Ole Hartvig; Frandsen, Lis; Schjerling, Peter

    2006-01-01

    Peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta (PGC-1alpha and PGC-1beta) were overexpressed by adenovirus-mediated gene transfer in cultures of primary rat skeletal muscle cells derived from neonatal myoblasts. Effects on muscle fiber type transition and metabolism...... an increase in the mRNA expression of TRB3, a negative regulator of insulin signaling. These results show that both PGC-1alpha and PGC-1beta are involved in the regulation of skeletal muscle fiber transition and metabolism and that they have both overlapping and differing effects....... were studied from days 5 to 22 of culture. PGC-1alpha and PGC-1beta overexpression caused a three- to fourfold increase in mRNA level, a doubling of enzymatic activity of citrate synthase, a slight increase in short-chain acyl-CoA dehydrogenase mRNA, a doubling of the mRNA level, and a 30-50% increase...

  16. Vacuum transitions in dual models

    International Nuclear Information System (INIS)

    Pashnev, A.I.; Volkov, D.V.; Zheltukhin, A.A.

    1976-01-01

    The investigation is continued of the spontaneous vacuum transition problem in the Neview-Schwartz dual model (NSDM). It is shown that vacuum transitions allow disclosing of supplementary degeneration in the resonance state spectrum. The dual amplitudes possess an internal structure corresponding to the presence of an infinite number of quarks with increasing masses and retained charges. The Adler principle holds. Analytic continuation on the constant of induced vacuum transitions makes it possible to establish the existence of spontaneous vacuum transitions in the NSDM. The consequence of this fact is the exact SU(2) symmetry of π, rho meson trajectories and the Higgs mechanism in the model. In this case the ratios of masses of particles leading trajectories are analogous to those obtained in the current algebra. It is shown that in the NSDM there arises chiral SU(2) x SU(2) x U(1) x U(1) x ... symmetry resulting from spontaneous vacuum transitions

  17. Energy transition, is it now?

    International Nuclear Information System (INIS)

    Combe, Matthieu; Thouverez, Pierre

    2016-06-01

    As French energy policy is now defined for energy transition, the contributions of this publication discuss implemented measures, what new laws will change, and what will be the consequences for industry. A first set of articles thus comments evolutions related to the implementation of energy transition in the building sector, how energy transition wants to get rid of wastage, how energy transition will impact the transport sector (public transports, car-pool and car sharing, bicycle, retail sector, airfields), and outline that President Hollande has fulfilled (nearly) all his commitments. The next article comments changes and critics made by the French constitutional Council on the law for energy transition. The next set of articles comments the results of an ADEME's study on bicycle kilometre allowance, discusses the issue of energy safety, and comments statements made by candidates to the French President election of 2012 on nuclear energy after the Fukushima accident

  18. Low level GAMMA0 spectrometry by beta-gamma coincidence

    International Nuclear Information System (INIS)

    Grigorescu, E.L.; Luca, A.; Razdolescu, A.C.; Ivan, C.

    1999-01-01

    Low level gamma spectrometry has a wide application, especially in environmental monitoring. Two variants, based on a beta-gamma coincidence technique, were studied. The equipment was composed of a beta detector and a Ge(Li) gamma detector (6% - relative efficiency), with the associated electronics. The gamma rays are recorded by the multichannel analyzer (4096 channels) only if the associated beta particles, which precede the gamma transitions, are registered in coincidence. Two types of beta detectors were used: plastic and liquid scintillators. In both cases, an external lead shield of 5 cm thick was used. The integral gamma background (50-1700 KeV) was reduced about 85 and 50 times, respectively. The corresponding MDA (Minimum Detectable Activity) values decreased about 1.5 and (3-7) times, respectively. The 2π sr plastic beta detector was placed on top the Ge(Li). The sample was inserted between the two detectors. The measurement time was 10 4 s. A 4π sr detector, built of the same material, was also studied, but it proved to be less advantageous because the background was reduced only 16 times; for a MDA reduction similar with that of the 2π sr variant, a longer measurement was needed (3.10 4 s). The other type of beta detector used, was a liquid scintillator. The dissolving of the samples in scintillator ensures a 4π sr measurement geometry. The vials with scintillator (10 ml volume) were placed on top the Ge(Li) and visualised by the photocathode of a phototube. This setup was surrounded by an enclosure which prevent the light penetration. The measurement time was 10 4 s. The only difficulty encountered in this low level measurement method is the accurate determination of the beta efficiency. A limitation is the possibility to measure only small mass samples. These variants are more simple and cheaper than others, previously studied. The advantage of the method is obvious when, instead of low MDA values, shorter measurement times are preferred. The

  19. Gamow-Teller beta decay of proton-rich nuclei

    International Nuclear Information System (INIS)

    Klepper, O.; Rykaczewski, K.

    1990-11-01

    The beta decays of 48 Mn and of even-even nuclei near the double shell-closures at 100 Sn and 146 Gd are currently investigated at the GSI on-line mass separator. Their Gamow-Teller strength are surveyed in their present experimental status, together with related results from the ISOLDE (CERN) and ISOCELE (Orsay) separators, and are compared with predictions from different nuclear models. The strength of the 0 + → 1 + Gamow-Teller transitions is compiled in tables and graphs. (orig.)

  20. Beta genus papillomaviruses and skin cancer.

    Science.gov (United States)

    Howley, Peter M; Pfister, Herbert J

    2015-05-01

    A role for the beta genus HPVs in keratinocyte carcinoma (KC) remains to be established. In this article we examine the potential role of the beta HPVs in cancer revealed by the epidemiology associating these viruses with KC and supported by oncogenic properties of the beta HPV proteins. Unlike the cancer associated alpha genus HPVs, in which transcriptionally active viral genomes are invariably found associated with the cancers, that is not the case for the beta genus HPVs and keratinocyte carcinomas. Thus a role for the beta HPVs in KC would necessarily be in the carcinogenesis initiation and not in the maintenance of the tumor. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Alpha and beta detection and spectrometry

    International Nuclear Information System (INIS)

    Saro, S.

    1984-01-01

    The theory of alpha and beta radioactive decay, the interaction of alpha and beta particles with matter, and their detection and spectrometry are dealt with in seven chapters: 1. Alpha transformation of atomic nuclei; 2. Basic properties of detectors and statistics of detection; 3. Alpha detectors and spectrometers; 4. Applications of alpha detection and spectrometry; 5. Beta transformation of atomic nuclei; 6. Beta particle detectors and spectrometers; 7. Detection of low energy beta particles. Chapter 8 is devoted to sampling and preparation of samples for radiometry. (E.F.)

  2. Antibodies against chromosomal beta-lactamase

    DEFF Research Database (Denmark)

    Giwercman, B; Rasmussen, J W; Ciofu, Oana

    1994-01-01

    A murine monoclonal anti-chromosomal beta-lactamase antibody was developed and an immunoblotting technique was used to study the presence of serum and sputum antibodies against Pseudomonas aeruginosa chromosomal group 1 beta-lactamase in patients with cystic fibrosis (CF). The serum antibody...... 1 cephalosporinase. We found a wide range of chromosomal beta-lactamase activity in the sputum samples, with no correlation with basal or induced activity of beta-lactamase expression. The presence of anti-beta-lactamase antibodies in endobronchial sputum could be an important factor in the defense...

  3. Kinetics and thermodynamics of hydrogen absorption and release in {beta}-titanium alloys; Kinetik und Thermodynamik der Wasserstoffaufnahme und -abgabe von {beta}-Titanlegierungen

    Energy Technology Data Exchange (ETDEWEB)

    Decker, M.; Christ, H.J. [Siegen Univ. (Gesamthochschule) (Germany). Inst. fuer Werkstofftechnik

    1998-12-31

    The work reported was intended to yield results allowing to describe as completely as possible the processes of interaction of {beta}-titanium and hydrogen. Three alloys have been selected for the experiments which suitably differ in stability of the {beta} phase. The characterisation of the hydrogen/metal interactions is primarily based on gravimetric measurements. A method was found to determine the diffusion coefficient of hydrogen, which is a significant variable for quantitative characterisation of the hydrogen absorption rate. (orig./CB) [Deutsch] In der Arbeit wird eine moeglichst vollstaendige Beschreibung der Wechselwirkung von {beta}-Titanlegierungen mit Wasserstoff angestrebt. Hierfuer wird mit drei Legierungen gearbeitet, die sich hinsichtlich der Stabilitaet der {beta}-Phase in sinnvoll abgestufter Weise unterscheiden. Fuer die Charakterisierung der Wasserstoff/Metall-Wechselwirkung wurden insbesondere gravimetrische Messungen eingesetzt. Weiterhin wurde die fuer eine quantitative Beschreibung der Wasserstoffaufnahmegeschwindigkeit wichtige Groesse des Diffusionskoeffizienten von Wasserstoff mit einem Verfahren bestimmt. (orig./MM)

  4. Controlled quantum evolutions and transitions

    Energy Technology Data Exchange (ETDEWEB)

    Petroni, Nicola Cufaro [INFN Sezione di Bari, INFM Unitadi Bari and Dipartimento Interateneo di Fisica dell' Universitae del Politecnico di Bari, Bari (Italy); De Martino, Salvatore; De Siena, Silvio; Illuminati, Fabrizio [INFM Unitadi Salerno, INFN Sezione di Napoli - Gruppo collegato di Salerno and Dipartimento di Fisica dell' Universitadi Salerno, Baronissi, Salerno (Italy)

    1999-10-29

    We study the nonstationary solutions of Fokker-Planck equations associated to either stationary or non stationary quantum states. In particular, we discuss the stationary states of quantum systems with singular velocity fields. We introduce a technique that allows arbitrary evolutions ruled by these equations to account for controlled quantum transitions. As a first significant application we present a detailed treatment of the transition probabilities and of the controlling time-dependent potentials associated to the transitions between the stationary, the coherent, and the squeezed states of the harmonic oscillator. (author)

  5. Measurement of the 2{nu}{beta}{beta} decay of {sup 100}Mo to the excited 0{sub 1}{sup +} state in the NEMO3 experiment

    Energy Technology Data Exchange (ETDEWEB)

    Vala, L

    2003-09-01

    The NEMO3 detector was designed for the study of double beta decay and in particular to search for the neutrinoless double beta decay process (0{nu}{beta}{beta}). The intended sensitivity in terms of a half-life limit for the 0{nu}{beta}{beta} decay is of the order of 10{sup 25} y which corresponds to an effective neutrino mass m{sub {nu}} on the level of (0.3 - 0.1) eV. The 0{nu}{beta}{beta} process is today the most promising test of the Majorana nature of the neutrino. The detector was constructed in the Modane Underground Laboratory (LSM) in France by an international collaboration including France, Russia, the Czech Republic, the USA, the UK, Finland, and Japan. The experiment has been taking data since May 2002. The quantity of {sup 100}Mo in the detector (7 kg) allows an efficient measurement of the two-neutrino double beta decay (2{nu}{beta}{beta}) of {sup 100}Mo to the excited 0{sub 1}{sup +} state (eeN{gamma} channel). Monte-Carlo simulations of the effect and of all the relative sources of background have been produced in order to define a set of appropriate selection criteria. Both Monte-Carlo simulations and special runs with sources of {sup 208}Tl and {sup 214}Bi showed that the only significant background in the eeN{gamma} channel comes from radon that penetrated inside the wire chamber of NEMO3. The experimental data acquired from May 2002 to May 2003 have been analysed in order to determine the signal from the 2{nu}{beta}{beta} decay of {sup 100}Mo to the excited 0{sub 1}{sup +} state and the corresponding background level. The physical result, which was obtained at the level of four standard deviations, is given in the form of an interval of half-life values at 95% confidence level: [5.84*10{sup 20}, 2.26*10{sup 21}] y for method A and [5.83*10{sup 20}, 1.71*10{sup 21}] y for method B. (author)

  6. Advanced Beta Dosimetry Techniques.Final Scientific/Technical Report

    International Nuclear Information System (INIS)

    David M. Hamby, PhD

    2006-01-01

    Final report describing NEER research on Advanced Beta Dosimetry Techniques. The research funded by this NEER grant establishes the framework for a detailed understanding of the challenges in beta dosimetry, especially in the presence of a mixed radiation field. The work also stimulated the thinking of the research group which will lead to new concepts in digital signal processing to allow collection of detection signals and real-time analysis such that simultaneous beta and gamma spectroscopy can take place. The work described herein (with detail in the many publications that came out of this research) was conducted in a manner that provided dissertation and thesis topics for three students, one of which was completely funded by this grant. The overall benefit of the work came in the form of a dramatic shift in signal processing that is normally conducted in pulse shape analysis. Analog signal processing was shown not to be feasible for this type of work and that digital signal processing was a must. This, in turn, led the research team to a new understanding of pulse analysis, one in which expands the state-of-the-art in simultaneous beta and gamma spectroscopy with a single detector

  7. Using the {Beta}-binomial distribution to characterize forest health

    Energy Technology Data Exchange (ETDEWEB)

    Zarnoch, S. J. [USDA Forest Service, Southern Research Station, Athens, GA (United States); Anderson, R.L.; Sheffield, R. M. [USDA Forest Service, Southern Research Station, Asheville, NC (United States)

    1995-03-01

    Forest health monitoring programs often use base variables which are dichotomous (i e. alive/dead, damaged/undamaged) to describe the health of trees. Typical sampling designs usually consist of randomly or systematically chosen clusters of trees for observation.It was claimed that contagiousness of diseases for example may result in non-uniformity of affected trees, so that distribution of the proportions, rather than simply the mean proportion, becomes important. The use of the {Beta}-binomial model was suggested for such cases. Use of the {Beta}-binomial distribution model applied in forest health analyses, was described.. Data on dogwood anthracnose (caused by Discula destructiva), a disease of flowering dogwood (Cornus florida L.), was used to illustrate the utility of the model. The {Beta}-binomial model allowed the detection of different distributional patterns of dogwood anthracnose over time and space. Results led to further speculation regarding the cause of the patterns. Traditional proportion analyses like ANOVA would not have detected the trends found using the {Beta}-binomial model, until more distinct patterns had evolved at a later date. The model was said to be flexible and require no special weighting or transformations of data.Another advantage claimed was its ability to handle unequal sample sizes.

  8. Beta activity measurements in high, variable gamma backgrounds

    International Nuclear Information System (INIS)

    Stanga, D.; Sandu, E.; Craciun, L.

    1997-01-01

    In many cases beta activity measurements must be performed in high and variable gamma backgrounds. In such instances it is necessary to use well-shielded detectors but this technique is limited to laboratory equipment and frequently insufficient. In order to perform in a simple manner beta activity measurements in high and variable backgrounds a software-aided counting technique have been developed and a counting system have been constructed. This technique combines the different counting techniques with traditional method of successive measurement of the sample and background. The counting system is based on a programmable multi-scaler which is endowed with appropriate software and allow all operations to be performed via keyboard in an interactive fashion. Two large - area proportional detectors were selected in order to have the same background and the same gamma response within 5%. A program has been developed for the counting data analysis and beta activity computing. The software-aided counting technique has been implemented for beta activity measurement in high and variable backgrounds. (authors)

  9. Application of inverse models and XRD analysis to the determination of Ti-17 {beta}-phase coefficients of thermal expansion

    Energy Technology Data Exchange (ETDEWEB)

    Freour, S. [GeM, Institut de Recherche en Genie Civil et Mecanique (UMR CNRS 6183), Universite de Nantes, Ecole Centrale de Nantes, 37 Boulevard de l' Universite, BP 406, 44 602 Saint-Nazaire cedex (France)]. E-mail: freour@crttsn.univ-nantes.fr; Gloaguen, D. [GeM, Institut de Recherche en Genie Civil et Mecanique (UMR CNRS 6183), Universite de Nantes, Ecole Centrale de Nantes, 37 Boulevard de l' Universite, BP 406, 44 602 Saint-Nazaire cedex (France); Francois, M. [Laboratoire des Systemes Mecaniques et d' Ingenierie Simultanee (LASMIS FRE CNRS 2719), Universite de Technologie de Troyes, 12 Rue Marie Curie, BP 2060, 10010 Troyes (France); Guillen, R. [GeM, Institut de Recherche en Genie Civil et Mecanique (UMR CNRS 6183), Universite de Nantes, Ecole Centrale de Nantes, 37 Boulevard de l' Universite, BP 406, 44 602 Saint-Nazaire cedex (France)

    2006-04-15

    scope of this work is the determination of the coefficients of thermal expansion of the Ti-17 {beta}-phase. A rigorous inverse thermo-elastic self-consistent scale transition micro-mechanical model extended to multi-phase materials was used. The experimental data required for the application of the inverse method were obtained from both the available literature and especially dedicated X-ray diffraction lattice strain measurements performed on the studied ({alpha} + {beta}) two-phase titanium alloy.

  10. Does Confucianism allow for body donation?

    Science.gov (United States)

    Jones, D Gareth; Nie, Jing-Bao

    2018-01-16

    Confucianism has been widely perceived as a major moral and cultural obstacle to the donation of bodies for anatomical purposes. The rationale for this is the Confucian stress on xiao (filial piety), whereby individuals' bodies are to be intact at death. In the view of many, the result is a prohibition on the donation of bodies to anatomy departments for the purpose of dissection. The role of dissection throughout the development of anatomy within a Confucian context is traced, and in contemporary China the establishment of donation programs and the appearance of memorial monuments is noted. In reassessing Confucian attitudes, the stress laid on a particular interpretation of filial piety is questioned, and an attempt is made to balance this with the Confucian emphasis on a moral duty to those outside one's immediate family. The authors argue that the fundamental Confucian norm ren (humaneness or benevolence) allows for body donation as people have a moral duty to help others. Moreover, the other central Confucian value, li (rites), offers important insights on how body donation should be performed as a communal activity, particularly the necessity of developing ethically and culturally appropriate rituals for body donation. In seeking to learn from this from a Western perspective, it is contended that in all societies the voluntary donation of bodies is a deeply human activity that is to reflect the characteristics of the community within which it takes place. This is in large part because it has educational and personal repercussions for students. Anat Sci Educ. © 2018 American Association of Anatomists. © 2018 American Association of Anatomists.

  11. Resident away rotations allow adaptive neurosurgical training.

    Science.gov (United States)

    Gephart, Melanie Hayden; Derstine, Pamela; Oyesiku, Nelson M; Grady, M Sean; Burchiel, Kim; Batjer, H Hunt; Popp, A John; Barbaro, Nicholas M

    2015-04-01

    Subspecialization of physicians and regional centers concentrate the volume of certain rare cases into fewer hospitals. Consequently, the primary institution of a neurological surgery training program may not have sufficient case volume to meet the current Residency Review Committee case minimum requirements in some areas. To ensure the competency of graduating residents through a comprehensive neurosurgical education, programs may need for residents to travel to outside institutions for exposure to cases that are either less common or more regionally focused. We sought to evaluate off-site rotations to better understand the changing demographics and needs of resident education. This would also allow prospective monitoring of modifications to the neurosurgery training landscape. We completed a survey of neurosurgery program directors and query of data from the Accreditation Council of Graduate Medical Education to characterize the current use of away rotations in neurosurgical education of residents. We found that 20% of programs have mandatory away rotations, most commonly for exposure to pediatric, functional, peripheral nerve, or trauma cases. Most of these rotations are done during postgraduate year 3 to 6, lasting 1 to 15 months. Twenty-six programs have 2 to 3 participating sites and 41 have 4 to 6 sites distinct from the host program. Programs frequently offset potential financial harm to residents rotating at a distant site by support of housing and transportation costs. As medical systems experience fluctuating treatment paradigms and demographics, over time, more residency programs may adapt to meet the Accreditation Council of Graduate Medical Education case minimum requirements through the implementation of away rotations.

  12. Assessing allowable take of migratory birds

    Science.gov (United States)

    Runge, M.C.; Sauer, J.R.; Avery, M.L.; Blackwell, B.F.; Koneff, M.D.

    2009-01-01

    Legal removal of migratory birds from the wild occurs for several reasons, including subsistence, sport harvest, damage control, and the pet trade. We argue that harvest theory provides the basis for assessing the impact of authorized take, advance a simplified rendering of harvest theory known as potential biological removal as a useful starting point for assessing take, and demonstrate this approach with a case study of depredation control of black vultures (Coragyps atratus) in Virginia, USA. Based on data from the North American Breeding Bird Survey and other sources, we estimated that the black vulture population in Virginia was 91,190 (95% credible interval = 44,520?212,100) in 2006. Using a simple population model and available estimates of life-history parameters, we estimated the intrinsic rate of growth (rmax) to be in the range 7?14%, with 10.6% a plausible point estimate. For a take program to seek an equilibrium population size on the conservative side of the yield curve, the rate of take needs to be less than that which achieves a maximum sustained yield (0.5 x rmax). Based on the point estimate for rmax and using the lower 60% credible interval for population size to account for uncertainty, these conditions would be met if the take of black vultures in Virginia in 2006 was < 3,533 birds. Based on regular monitoring data, allowable harvest should be adjusted annually to reflect changes in population size. To initiate discussion about how this assessment framework could be related to the laws and regulations that govern authorization of such take, we suggest that the Migratory Bird Treaty Act requires only that take of native migratory birds be sustainable in the long-term, that is, sustained harvest rate should be < rmax. Further, the ratio of desired harvest rate to 0.5 x rmax may be a useful metric for ascertaining the applicability of specific requirements of the National Environmental Protection Act.

  13. [Solubilization Specificities Interferon beta-1b from Inclusion Bodies].

    Science.gov (United States)

    Zhuravko, A S; Kononova, N V; Bobruskin, A I

    2015-01-01

    A new solubilization method of recombinant interferon beta-1b (IFNβ-1b) from the inclusion bodies was developed. This method allows to extract the target protein selectively in the solutions of different alcohols, such as ethanol, propanol and isopropanol. It was shown that the more effective IFNβ-1b solubilization was achieved in the 55% propanol solution. This method allowed to extract the target protein from inclusion bodies around 85-90%, and significantly reduced Escherichia coli content in the solubilizate, in comparison with standard methods.

  14. Spectrofluorimetric determination of stoichiometry and association constants of the complexes of harmane and harmine with beta-cyclodextrin and chemically modified beta-cyclodextrins.

    Science.gov (United States)

    Martín, L; León, A; Olives, A I; Del Castillo, B; Martín, M A

    2003-06-13

    The association characteristics of the inclusion complexes of the beta-carboline alkaloids harmane and harmine with beta-cyclodextrin (beta-CD) and chemically modified beta-cyclodextrins such as hydroxypropyl-beta-cyclodextrin (HPbeta-CD), 2,3-di-O-methyl-beta-cyclodextrin (DMbeta-CD) and 2,3,6-tri-O-methyl-beta-cyclodextrin (TMbeta-CD) are described. The association constants vary from 112 for harmine/DMbeta-CD to 418 for harmane/HPbeta-CD. The magnitude of the interactions between the host and the guest molecules depends on the chemical and geometrical characteristics of the guest molecules and therefore the association constants vary for the different cyclodextrin complexes. The steric hindrance is higher in the case of harmine due to the presence of methoxy group on the beta-carboline ring. The association obtained for the harmane complexes is stronger than the one observed for harmine complexes except in the case of harmine/TMbeta-CD. Important differences in the association constants were observed depending on the experimental variable used in the calculations (absolute value of fluorescence intensity or the ratio between the fluorescence intensities corresponding to the neutral and cationic forms). When fluorescence intensity values were considered, the association constants were higher than when the ratio of the emission intensity for the cationic and neutral species was used. These differences are a consequence of the co-existence of acid-base equilibria in the ground and in excited states together with the complexation equilibria. The existence of a proton transfer reaction in the excited states of harmane or harmine implies the need for the experimental dialysis procedure for separation of the complexes from free harmane or harmine. Such methodology allows quantitative results for stoichiometry determinations to be obtained, which show the existence of both 1:1 and 1:2 beta-carboline alkaloid:CD complexes with different solubility properties.

  15. DMPD: Immunoreceptor-like signaling by beta 2 and beta 3 integrins. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 17913496 Immunoreceptor-like signaling by beta 2 and beta 3 integrins. Jakus Z, Fod...) Show Immunoreceptor-like signaling by beta 2 and beta 3 integrins. PubmedID 17913496 Title Immunoreceptor-...like signaling by beta 2 and beta 3 integrins. Authors Jakus Z, Fodor S, Abram CL

  16. Experiments close to the beta-limit in W7-AS

    International Nuclear Information System (INIS)

    Weller, A; Geiger, J; Werner, A; Zarnstorff, M C; Nuehrenberg, C; Sallander, E; Baldzuhn, J; Brakel, R; Burhenn, R; Dinklage, A; Fredrickson, E; Gadelmeier, F; Giannone, L; Grigull, P; Hartmann, D; Jaenicke, R; Klose, S; Knauer, J P; Koenies, A; Kolesnichenko, Ya I; Laqua, H P; Lutsenko, V V; McCormick, K; Monticello, D; Osakabe, M; Pasch, E; Reiman, A; Rust, N; Spong, D A; Wagner, F; Yakovenko, Yu V

    2003-01-01

    A major objective of the experimental program in the last phase of the W7-AS stellarator was to explore and demonstrate the high-beta performance of advanced stellarators. MHD-quiescent discharges at low impurity radiation levels with volume averaged beta-values of up to beta=3.4% have been achieved. A very important prerequisite was the attainment of the high density H-Mode (HDH) regime. This was made possible by the installation of extensive graphite plasma facing components designed for island divertor operation. The co-directed neutral beam injection provided increased absorbed heating power of up to 3.2 MW in high-beta plasmas with B<=1.25 T. The anticipated improved features concerning equilibrium and stability at high plasma beta could be verified experimentally by the comparison of x-ray data with free boundary equilibrium calculations. The maximum beta found in configurations with a rotational transform around t=0.5 is determined by the available heating power. No evidence of a stability limit has been found in the accessible configuration space, and the discharges are remarkably quiescent at maximum beta, most likely due the increase of the magnetic well depth. An increase in low m/n MHD activity is typically observed during the transition towards high beta. The beneficial stability properties of net-current-free configurations could be demonstrated by comparison with configurations where a significant inductive current drive was involved. Current driven instabilities such as tearing modes and soft disruptions can prevent access to beta-values as high as in the currentless case. The experimental results indicate that optimized stellarators such as W7-X can be considered as a viable option for an attractive stellarator fusion reactor

  17. Beta Cell Mass Restoration in Alloxan-Diabetic Mice Treated with EGF and Gastrin.

    Directory of Open Access Journals (Sweden)

    Imane Song

    Full Text Available One week of treatment with EGF and gastrin (EGF/G was shown to restore normoglycemia and to induce islet regeneration in mice treated with the diabetogenic agent alloxan. The mechanisms underlying this regeneration are not fully understood. We performed genetic lineage tracing experiments to evaluate the contribution of beta cell neogenesis in this model. One day after alloxan administration, mice received EGF/G treatment for one week. The treatment could not prevent the initial alloxan-induced beta cell mass destruction, however it did reverse glycemia to control levels within one day, suggesting improved peripheral glucose uptake. In vitro experiments with C2C12 cell line showed that EGF could stimulate glucose uptake with an efficacy comparable to that of insulin. Subsequently, EGF/G treatment stimulated a 3-fold increase in beta cell mass, which was partially driven by neogenesis and beta cell proliferation as assessed by beta cell lineage tracing and BrdU-labeling experiments, respectively. Acinar cell lineage tracing failed to show an important contribution of acinar cells to the newly formed beta cells. No appearance of transitional cells co-expressing insulin and glucagon, a hallmark for alpha-to-beta cell conversion, was found, suggesting that alpha cells did not significantly contribute to the regeneration. An important fraction of the beta cells significantly lost insulin positivity after alloxan administration, which was restored to normal after one week of EGF/G treatment. Alloxan-only mice showed more pronounced beta cell neogenesis and proliferation, even though beta cell mass remained significantly depleted, suggesting ongoing beta cell death in that group. After one week, macrophage infiltration was significantly reduced in EGF/G-treated group compared to the alloxan-only group. Our results suggest that EGF/G-induced beta cell regeneration in alloxan-diabetic mice is driven by beta cell neogenesis, proliferation and recovery of

  18. The versatile enzyme Araf51 allowed efficient synthesis of rare pathogen-related beta-D-galactofuranosyl-pyranoside disaccharides

    Czech Academy of Sciences Publication Activity Database

    Chlubnová, I.; Králová, B.; Dvořáková, H.; Hošek, P.; Spiwok, V.; Filipp, Dominik; Nugier-Chauvin, C.; Daniellou, R.; Ferrieres, V.

    2014-01-01

    Roč. 12, č. 19 (2014), s. 3080-3089 ISSN 1477-0520 Grant - others:GA MŠk(CZ) LM2010005 Institutional support: RVO:68378050 Keywords : Galactofuranosyl-pyranoside dipeptides * Araf51 enzymatic synthesis * computer modelling Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.562, year: 2014

  19. Computational study of the fibril organization of polyglutamine repeats reveals a common motif identified in beta-helices.

    Science.gov (United States)

    Zanuy, David; Gunasekaran, Kannan; Lesk, Arthur M; Nussinov, Ruth

    2006-04-21

    The formation of fibril aggregates by long polyglutamine sequences is assumed to play a major role in neurodegenerative diseases such as Huntington. Here, we model peptides rich in glutamine, through a series of molecular dynamics simulations. Starting from a rigid nanotube-like conformation, we have obtained a new conformational template that shares structural features of a tubular helix and of a beta-helix conformational organization. Our new model can be described as a super-helical arrangement of flat beta-sheet segments linked by planar turns or bends. Interestingly, our comprehensive analysis of the Protein Data Bank reveals that this is a common motif in beta-helices (termed beta-bend), although it has not been identified so far. The motif is based on the alternation of beta-sheet and helical conformation as the protein sequence is followed from the N to the C termini (beta-alpha(R)-beta-polyPro-beta). We further identify this motif in the ssNMR structure of the protofibril of the amyloidogenic peptide Abeta(1-40). The recurrence of the beta-bend suggests a general mode of connecting long parallel beta-sheet segments that would allow the growth of partially ordered fibril structures. The design allows the peptide backbone to change direction with a minimal loss of main chain hydrogen bonds. The identification of a coherent organization beyond that of the beta-sheet segments in different folds rich in parallel beta-sheets suggests a higher degree of ordered structure in protein fibrils, in agreement with their low solubility and dense molecular packing.

  20. Diffusion of Hydrogen in the beta-Phase of Pd-H Studied by Small Energy Transfer Neutron Scattering

    Energy Technology Data Exchange (ETDEWEB)

    Nelin, G; Skoeld, K

    1974-07-01

    The diffusion of hydrogen in beta-PdH has been studied by quasielastic neutron scattering. It is shown that the diffusion occurs through jumps between adjacent octahedral interstitial sites. The observed integrated quasielastic intensities cannot be described by a simple Debye-Waller factor. The phase transition from the beta-phase to the alpha-phase has also been studied. No dramatic changes in the scattering patterns were observed. It is concluded that the diffusion mechanism is remarkably similar between the low concentration alpha-phase and the high concentration beta-phase

  1. Comparisons of experimental beta-ray spectra important to decay heat predictions with ENSDF [Evaluated Nuclear Structure Data File] evaluations

    International Nuclear Information System (INIS)

    Dickens, J.K.

    1990-03-01

    Graphical comparisons of recently obtained experimental beta-ray spectra with predicted beta-ray spectra based on the Evaluated Nuclear Structure Data File are exhibited for 77 fission products having masses 79--99 and 130--146 and lifetimes between 0.17 and 23650 sec. The comparisons range from very poor to excellent. For beta decay of 47 nuclides, estimates are made of ground-state transition intensities. For 14 cases the value in ENSDF gives results in very good agreement with the experimental data. 12 refs., 77 figs., 1 tab

  2. The structure of nuclei far from beta stability

    International Nuclear Information System (INIS)

    Zganjar, E.F.

    1990-01-01

    This report discusses the following topics: shape coexistence, intruder states, and E0 transitions; the Ir isotopes; the Pt isotopes; the Au isotopes; the Hg isotopes; the Tl isotopes; decay properties of 153 Yb and 153 Tm; non-yrast levels structure of 135 Nd via beta decay of 135 Pm; decay of mass-separated 137 Eu and 137 Sm; structure of 130,132 Ce, 132,134 Nd, and 134 Pm; decay of 127 Cs to levels of odd-neutron 127 Xe; level structure of 119 Te; conversion electron spectroscopy in 116 Xe and 126 Xe; signature of the shape coexistence in 72 Kr; identification of transitions in 73 Kr and search for large oblate; high spin states and multiple band structure in 68 Ge; high spin states in 65 Ga and 67 Ga; electron spectroscopy; ion sources; and the on-line nuclear orientation facility

  3. New results for double-beta decay of {sup 100}Mo to excited final states of {sup 100}Ru using the TUNL-ITEP apparatus

    Energy Technology Data Exchange (ETDEWEB)

    Kidd, M.F.; Esterline, J.H. [Department of Physics, Duke University and Triangle Universities Nuclear Laboratory, Durham, NC 27708-0308 (United States); Tornow, W. [Department of Physics, Duke University and Triangle Universities Nuclear Laboratory, Durham, NC 27708-0308 (United States)], E-mail: tornow@tunl.duke.edu; Barabash, A.S.; Umatov, V.I. [Institute for Theoretical and Experimental Physics, 117259 Moscow (Russian Federation)

    2009-04-15

    The coincidence detection efficiency of the TUNL-ITEP apparatus designed for measuring half-life times of two-neutrino double-beta (2{nu}{beta}{beta}) decay transitions to excited final states in daughter nuclei has been measured with a factor of 2.4 improved accuracy. In addition, the previous measuring time of 455 days for the study of the {sup 100}Mo 2{nu}{beta}{beta} decay to the first excited 0{sub 1}{sup +} state in {sup 100}Ru has been increased by 450 days, and a new result (combined with the previous measurement obtained with the same apparatus) for this transition is presented: T{sub 1/2}=[5.5{sub -0.8}{sup +1.2}(stat){+-}0.3(syst)]x10{sup 20} yr. Measured 2{nu}{beta}{beta} decay half-life times to excited states can be used to test the reliability of nuclear matrix element calculations needed for determining the effective neutrino mass from zero-neutrino double-beta decay data. We also present new limits for transitions to higher excited states in {sup 100}Ru which, if improved, may be of interest for more exotic conjectures, like a bosonic component to neutrino statistics.

  4. Beta decay and muon capture rates in a self-consistent relativistic framework

    Energy Technology Data Exchange (ETDEWEB)

    Marketin, Tomislav; Paar, Nils; Niksic, Tamara; Vretenar, Dario [Physics Department, Faculty of Science, University of Zagreb (Croatia); Ring, Peter [Physik-Department, Technische Universitaet Muenchen, D-85748 Muenchen (Germany)

    2009-07-01

    A fully consistent calculation of muon capture and beta decay rates is presented, based on a microscopic theoretical framework describing the semileptonic weak interaction processes. Nuclear ground state is determined using the Relativistic Hartree-Bogolyubov (RHB) model with density dependent meson-nucleon coupling constants, and transition rates are calculated via proton-neutron relativistic quasiparticle RPA using the same interaction as in the RHB equations. Muon capture rates are calculated for a wide range of nuclei along the valley of stability, from {sup 12}C to {sup 244}Pu, with accuracy of approximately 30%, using the interaction DD-ME2. Previous studies of beta decay rates have only taken into account Gamow-Teller transitions. We extend this approach by including forbidden transitions and systematically study their contribution to decay rates of exotic nuclei along the r-process path, which are important for constraining the conditions in which nucleosynthesis takes place.

  5. Background constrains of the SuperNEMO experiment for neutrinoless double beta-decay searches

    Energy Technology Data Exchange (ETDEWEB)

    Povinec, Pavel P.

    2017-02-11

    The SuperNEMO experiment is a new generation of experiments dedicated to the search for neutrinoless double beta-decay, which if observed, would confirm the existence of physics beyond the Standard Model. It is based on the tracking and calorimetry techniques, which allow the reconstruction of the final state topology, including timing and kinematics of the double beta-decay transition events, offering a powerful tool for background rejection. While the basic detection strategy of the SuperNEMO detector remains the same as of the NEMO-3 detector, a number of improvements were accomplished for each of detector main components. Upgrades of the detector technologies and development of low-level counting techniques ensure radiopurity control of construction parts of the SuperNEMO detector. A reference material made of glass pellets has been developed to assure quality management and quality control of radiopurity measurements. The first module of the SuperNEMO detector (Demonstrator) is currently under construction in the Modane underground laboratory. No background event is expected in the neutrinoless double beta-decay region in 2.5 years of its operation using 7 kg of {sup 82}Se. The half-life sensitivity of the Demonstrator is expected to be >6.5·10{sup 24} y, corresponding to an effective Majorana neutrino mass sensitivity of |0.2−0.4| eV (90% C.L.). The full SuperNEMO experiment comprising of 20 modules with 100 kg of {sup 82}Se source should reach an effective Majorana neutrino mass sensitivity of |0.04−0.1| eV, and a half-life limit 1·10{sup 26} y. - Highlights: • SuperNEMO detector for 2β0ν-decay of {sup 82}Se should reach half-life limit of 10{sup 26} y. • Radiopurity of the SuperNEMO internal detector parts was checked down to 0.1 mBq/kg. • Reference material of glass pellets was developed for underground γ-spectrometry.

  6. Metalo-beta-lactamases Metallo-beta-lactamases

    Directory of Open Access Journals (Sweden)

    Rodrigo Elisandro Mendes

    2006-04-01

    Full Text Available Nos últimos anos tem sido observada maior incidência de bacilos Gram-negativos resistentes a cefalosporinas de espectro ampliado no ambiente hospitalar, ocasionando, assim, maior uso de betalactâmicos mais potentes, como os carbapenens. A utilização de carbapenens exerce maior pressão seletiva sobre a microbiota hospitalar, o que pode ocasionar aumento da resistência a esses agentes. Entre os mecanismos de resistência a carbapenens mais comumente identificados estão a produção de betalactamases, como, por exemplo, as pertencentes à classe D de Ambler e as que pertencem à classe B de Ambler, ou metalo-beta-lactamases (MbetaL. Essas últimas hidrolisam todos betalactâmicos comercialmente disponíveis, sendo a única exceção o monobactam aztreonam. Desde o início da década de 1990, novos genes que codificam MbetaLs têm sido descritos em microrganismos clinicamente importantes, como Pseudomonas spp., Acinetobacter spp. e membros da família Enterobacteriaceae. O encontro desses microrganismos não-sensíveis a carbapenens pode ser submetido a metodologias fenotípicas para detecção da produção de MbetaL com o intuito de auxiliar a Comissão de Controle de Infecção Hospitalar (CCIH e prevenir a disseminação desses determinantes de resistência, uma vez que genes que codificam MbetaLs estão contidos em estruturas genéticas que propiciam sua mobilidade de forma muito efetiva, sendo então facilmente disseminados.Increase isolation of Gram-negative bacilli resistant to broad-spectrum cephalosporin has been observed during the last few years, thus determining the use of more potent beta-lactams, such as carbapenems. The use of these antimicrobial agents may lead to the emergence of carbapenem resistant Gram-negative bacilli in the nosocomial environment. Carbapenem resistance may be due to the production of Ambler class D beta-lactamase or Ambler class B beta-lactamase, also called metallo-beta-lactamase (MbetaL. Apart from

  7. 20F beta spectrum shape and weak interaction tests

    Science.gov (United States)

    Voytas, Paul; George, Elizabeth; Chuna, Thomas; Naviliat-Cuncic, Oscar; Hughes, Max; Huyan, Xueying; Minamisono, Kei; Paulauskas, Stanley

    2016-09-01

    Precision measurements of the shape of beta spectra can test our understanding of the weak interaction. We are carrying out a measurement of the shape of the energy spectrum of β particles from 20F decay. The primary motivation is to test the so-called strong form of the conserved vector current (CVC) hypothesis. The measurement should also enable us to place competitive limits on the contributions of exotic tensor couplings in beta decay. We aim to achieve a relative precision better than 3% on the linear contribution to the shape. This represents an order of magnitude improvement compared to previous experiments in 20F. In order to control systematic effects, we are using a technique that takes advantage of high energy radioactive beams at the NSCL to implant the decaying nuclei in scintillation detectors deeply enough that the emitted beta particles cannot escape. The β-particle energy is measured with the implantation detector after switching off the implantation beam. Ancillary detectors are used to identify the 1.633-MeV γ-rays following the 20F β decay for coincidence measurements in order to tag the transition of interest and to reduce backgrounds. We report on the status of the analysis. Supported in part with Awards from the NSCL PAC and the National Science Foundation under Grant No. PHY-1506084.

  8. On Determinism in Modal Transition Systems

    DEFF Research Database (Denmark)

    Benes, Nikola; Kretinsky, Jan; Larsen, Kim Guldstrand

    2009-01-01

    Modal transition systems (MTS) is a formalism which extends the classical notion of labelled transition systems by introducing transitions of two types: must transitions that have to be present in any implementation of the MTS and may transitions that are allowed but not required. The MTS framewo....... In the present article, we provide a comprehensive account of the MTS framework in the deterministic setting. We study a number of problems previously considered on MTS and point out to what extend we can expect better results under the restriction of determinism....

  9. Transit space

    DEFF Research Database (Denmark)

    Raahauge, Kirsten Marie

    2008-01-01

    This article deals with representations of one specific city, Århus, Denmark, especially its central district. The analysis is based on anthropological fieldwork conducted in Skåde Bakker and Fedet, two well-off neighborhoods. The overall purpose of the project is to study perceptions of space...... and the interaction of cultural, social, and spatial organizations, as seen from the point of view of people living in Skåde Bakker and Fedet. The focus is on the city dwellers’ representations of the central district of Århus with specific reference to the concept of transit space. When applied to various Århusian...

  10. Transition region

    International Nuclear Information System (INIS)

    Jordan, C.

    1977-01-01

    The Glossary is designed to be a technical dictionary that will provide solar workers of various specialties, students, other astronomers and theoreticians with concise information on the nature and the properties of phenomena of solar and solar-terrestrial physics. Each term, or group of related terms, is given a concise phenomenological and quantitative description, including the relationship to other phenomena and an interpretation in terms of physical processes. The references are intended to lead the non-specialist reader into the literature. This section deals with: transition region; di-electronic recombination; intersystem or intercombination lines; satellite lines; grazing-incidence optics; and crystal spectrometers. (B.R.H.)

  11. Developments for the 6He beta - nu angular correlation experiment

    Science.gov (United States)

    Zumwalt, David W.

    This thesis describes developments toward the measurement of the angular correlation between the beta and the antineutrino in the beta decay of 6He. This decay is a pure Gamow-Teller decay which is described in the Standard Model as a purely axial vector weak interaction. The angular correlation is characterized by the parameter abetanu = -1/3 in the Standard Model. Any deviation from this value would be evidence for tensor components in the weak interaction and would constitute new physics. A new method will be used to measure the parameter a betanu from 6He decays, featuring a magneto-optical trap that will measure the beta particle in coincidence with the recoiling 6Li daughter ion. This neutral atom trapping scheme provides cold, tightly confined atoms which will reduce systematic uncertainties related to the initial position of the decay. By knowing the initial position of the decay and measuring the time of flight of the recoiling 6Li daughter ion in coincidence with the beta, the angular correlation between the beta and the antineutrino can be deduced. We aim to measure a betanu first to the level of 1%, and eventually to the 0.1% level, which would represent an order of magnitude improvement in precision over past experiments. Towards this goal, we have designed, built, and successfully tested a liquid lithium target to provide >2×10. {10} 6He atoms/sto a low-background environment, which is the most intense source of 6He presently available. This allowed for an additional measurement of the 6He half-life (806.89 +/- 0.11stat +0.23-0.19syst ms) to be made with unprecedented precision, resolving discrepancies in past measurements. We have also tested our trapping and detection apparatus and have begun to record preliminary coincidence events.

  12. Biotinylated human. beta. -endorphins as probes for the opioid receptor

    Energy Technology Data Exchange (ETDEWEB)

    Hochhaus, G.; Gibson, B.W.; Sadee, W.

    1988-01-05

    The reaction of human ..beta..-endorphin and biotinyl N-hydroxysuccinimide with or without spacer arm, afforded a series of products that were separated by high performance liquid chromatography (HPLC). Liquid secondary ion mass spectrometry of the biotinylated products and their tryptic digests produced abundant protonated molecular ions (MH/sup +/), which specified the number and location of biotinylation. Between 1 and 4 biotinyl residues were incorporated per human ..beta..-endorphin molecule, at Lys-9, -19, -24, -28, and -29, but not at the amino-terminal Try-1. Three HPLC fractions were isolated for receptor binding studies monobiotinylation of Lys-9, Lys-19, and a mixture of Lys-24, Lys-28, and Lys-29 derivatives. IC/sub 50/ values for binding to ..mu.. and delta opioid receptor sites were 3-8 times higher for monobiotinylated derivatives than for the parent human ..beta..-endorphin. Association with avidin decreased opioid receptor affinities for the C/sub 6/ spacer derivative biotinylated at position Lys-9, which is close to the (1-5) enkephalin receptor region. In contrast, avidin did not affect or even increased apparent affinities to ..mu.. and delta sites for derivatives biotinylated at the ..cap alpha..-helical part of the molecule (Lys-19, -24, -28, and -29). Biotinylated human ..beta..-endorphins also bound to low affinity nonopioid binding sites on NG-108-15 cells; however, affinities to these sites were considerably reduced when derivatives were bound to avidin. The ability of biotinylated human ..beta..-endorphin to cross-link the ..mu.. and delta opioid receptors to avidin allows application of the biotin-avidin system as a molecular probe of the opioid receptor.

  13. Resistance training & beta-hydroxy-beta-methylbutyrate supplementation on hormones

    Directory of Open Access Journals (Sweden)

    Hamid Arazi

    2015-10-01

    Full Text Available RESUMOIntroduction:In recent years, there was an increased interest on the effects of beta-hydroxy-beta-methylbutyrate (HMB supplementation on skeletal muscle due to its anti-catabolic effects.Objectives:To investigate the effect of HMB supplementation on body composition, muscular strength and anabolic-catabolic hormones after resistance training.Methods:Twenty amateur male athletes were randomly assigned to supplement and control groups in a double-blind crossover design and participated in four weeks resistance training. Before and after the test period fasting blood samples were obtained to determine anabolic (the growth hormone and testosterone and catabolic (cortisol hormones, and fat mass, lean body mass (LBM and muscular strength were measured. Dependent and independent t-tests were used to analyze data.Results:After the training period, there were no significant differen-ces between the groups with respect to fat mass, LBM and anabolic-catabolic hormones. HMB supplementation resulted in a significantly greater strength gain (p≤0.05.Conclusion:Greater increase in strength for HMB group was not accompanied by body composition and basal circulating anabolic-catabolic hormonal changes. It seems that HMB supplementation may have beneficial effects on neurological adaptations of strength gain.

  14. Electrets for beta radiation detection

    International Nuclear Information System (INIS)

    Campos, L.L.; Caldas, L.V.E.; Mascarenhas, S.

    1983-01-01

    Electret dosimetry has been reviewed by Gross. A cylindrical electret ionization-chamber type dosimeter has been studied for X and gamma rays and neutrons. The principle of the dosimeter is electret charge compensation due to ionization in the chamber volume. Electret ionization chambers can be designed with one or more electrets and in various shapes. This study is concerned with a simple system, similar to a cylindrical ionization chamber (sensitive volume: 3,5 cm 3 ) using teflon electrets. Aluminum and lucite were used as wall-materials. Other experiences were performed using chambers without wall, i.e., without defined sensitive volume. The teflon electrets were obtained by Corona discharge in the gas surrounding them. The measurement of the electret charge was made by induction using a co-axial insulated metal chamber connected to an electrometer Keithley 610C. By measuring the charge before and after irradiation it is possible to obtain a calibration curve: charge (Q) versus absorbed dose (D) for the dosimeter. The irradiation setup used was the Beta Secondary Standard System of IPEN calibration laboratory with four beta sources: 90 Sr 90 Y (74 and 1850 MBq), 204 Tl (18,5 MBq) and 147 Pm (518 MBq). In some cases a 85 Kr source was also used. The electrets were tested in different radiation field geometries: electret axis parallel and perpendicular to the field. In conclusion, depending on the wall material and radiation field geometry, the teflon electret detector can be used for different dose interval determinations, using beta radiation

  15. Transitional issues

    International Nuclear Information System (INIS)

    1998-01-01

    This discussion paper, the fifth in the series developed at the IPPSO Market Design Conference, addressed the issue of the need to prevent Ontario Hydro from taking unfair advantage of independent producers and other stakeholders through activities and investments in new power generating capacity in the transitional period leading up to deregulation. The need for controls is predicated on the assumption that the short-term actions and investments of Ontario Hydro could seriously compromise the position of independent generators, and that without such controls the level playing field essential to the operation of a competitive market, does not exist. Various actual and potential actions of Ontario Hydro were discussed, all of which point to the need for strict controls over Ontario Hydro exercising its dominant market power in an unfair way. It was recommended that as a minimum, the provincial government should no longer provide guarantees for Ontario Hydro capital projects, and that Ontario Hydro be instructed to defer any investment on new or returning generating capacity until the new market is in place. Limits could also be placed on Ontario Hydro's marketing efforts to enter into contracts during the transition period, and Ontario Hydro and municipal utilities should be required to keep separate accounts of their commercial preparation, and to settle such accounts separate from ratepayer revenue

  16. 76 FR 16629 - Federal Travel Regulation (FTR); Relocation Allowances-Relocation Income Tax Allowance (RITA) Tables

    Science.gov (United States)

    2011-03-24

    ... other FTR Bulletins can be found at http://www.gsa.gov/ftrbulletin . The RIT allowance tables are located at http://www.gsa.gov/relocationpolicy . DATES: This notice is effective March 24, 2011. FOR... CFR part 301-17 Appendices A through D. The tables will be published at http://www.gsa.gov...

  17. 78 FR 26637 - Federal Travel Regulation (FTR); Relocation Allowance-Relocation Income Tax (RIT) Allowable Tables

    Science.gov (United States)

    2013-05-07

    ...: The GSA published FTR Amendment 2008-04, in the Federal Register on June 25, 2008 (73 FR 35952), specifying that GSA would no longer publish the RIT Allowance tables in Title 41 of the Code of Federal..., 2013. Carolyn Austin-Diggs, Principal Deputy Administrator, Office of Asset and Transportation...

  18. Abstraction Mechanisms in the BETA Programming Language

    DEFF Research Database (Denmark)

    Kristensen, Bent Bruun; Madsen, Ole Lehrmann; Møller-Pedersen, Birger

    1983-01-01

    . It is then necessary that the abstraction mechanisms are powerful in order to define more specialized constructs. BETA is an object oriented language like SIMULA 67 ([SIMULA]) and SMALLTALK ([SMALLTALK]). By this is meant that a construct like the SIMULA class/subclass mechanism is fundamental in BETA. In contrast......]) --- covering both data, procedural and control abstractions, substituting constructs like class, procedure, function and type. Correspondingly objects, procedure activation records and variables are all regarded as special cases of the basic building block of program executions: the entity. A pattern thus......The BETA programming language is developed as part of the BETA project. The purpose of this project is to develop concepts, constructs and tools in the field of programming and programming languages. BETA has been developed from 1975 on and the various stages of the language are documented in [BETA...

  19. GERDA - a new neutrinoless double beta experiment using 76Ge

    International Nuclear Information System (INIS)

    Meierhofer, G

    2011-01-01

    The search for neutrinoless double beta decay (0νssss) has been a very active field for the last decades. While double beta decay has been observed, 0νssss decay still waits for its experimental proof. The GErmanium Detector Array (GERDA) uses 76 Ge, an ideal candidate as it is acting as source and detector simultaneously. Germanium detectors, isotopically enriched in 76 Ge are submerged directly into an ultra pure cryo liquid, which serves as coolant and radiation shield. This concept will allow to reduce the background by up to two orders of magnitude with respect to earlier experiments. GERDA has been constructed in hall A of the underground laboratory LNGS of the INFN in Italy. The experiment started recently with a test run.

  20. Properties of an extrapolation chamber for beta radiation dosimetry

    International Nuclear Information System (INIS)

    Caldas, L.V.E.

    The properties of a commercial extrapolation chamber were studied, and the possibility is shown of its use in beta radiation dosimetry. The chamber calibration factors were determined for several sources ( 90 Sr, 90 Y- 204 Tl and 147 Pm) making known the dependence of its response on the energy of the incident radiation. Extrapolation curves allow to obtain independence on energy for each source. One of such curves, shown for the 90 Sr- 90 Y source at 50 cm from the detector, is obtained through the variation of the chamber window thickness and the extrapolation to the null distance (determined graphically). Different curves shown also: 1) the dependence of the calibration factor on the average energy of beta radiation; 2) the variation of ionization current with the distance between the chamber and the sources; 3) the effect of the collecting electrode area on the value of calibration factors for the different sources. (I.C.R.) [pt

  1. High-beta linac structures

    International Nuclear Information System (INIS)

    Schriber, S.O.

    1979-01-01

    Accelerating structures for high-beta linacs that have been and are in use are reviewed in terms of their performance. Particular emphasis is given to room-temperature structures and the disk-and-washer structure. The disk-and-washer structure has many attractive features that are discussed for pulsed high-gradient linacs, for 100% duty-cycle medium-gradient linacs and for high-current linacs requiring maximal amounts of stored energy in the electric fields available to the beam

  2. Ionizing radiation predisposes non-malignant human mammaryepithelial cells to undergo TGF beta-induced epithelial to mesenchymaltransition

    Energy Technology Data Exchange (ETDEWEB)

    Andarawewa, Kumari L.; Erickson, Anna C.; Chou, William S.; Costes, Sylvain; Gascard, Philippe; Mott, Joni D.; Bissell, Mina J.; Barcellos-Hoff, Mary Helen

    2007-04-06

    Transforming growth factor {beta}1 (TGF{beta}) is a tumor suppressor during the initial stage of tumorigenesis, but it can switch to a tumor promoter during neoplastic progression. Ionizing radiation (IR), both a carcinogen and a therapeutic agent, induces TGF{beta}, activation in vivo. We now show that IR sensitizes human mammary epithelial cells (HMEC) to undergo TGF{beta}-mediated epithelial to mesenchymal transition (EMT). Non-malignant HMEC (MCF10A, HMT3522 S1 and 184v) were irradiated with 2 Gy shortly after attachment in monolayer culture, or treated with a low concentration of TGF{beta} (0.4 ng/ml), or double-treated. All double-treated (IR+TGF{beta}) HMEC underwent a morphological shift from cuboidal to spindle-shaped. This phenotype was accompanied by decreased expression of epithelial markers E-cadherin, {beta}-catenin and ZO-1, remodeling of the actin cytoskeleton, and increased expression of mesenchymal markers N-cadherin, fibronectin and vimentin. Furthermore, double-treatment increased cell motility, promoted invasion and disrupted acinar morphogenesis of cells subsequently plated in Matrigel{trademark}. Neither radiation nor TGF{beta} alone elicited EMT, even though IR increased chronic TGF{beta} signaling and activity. Gene expression profiling revealed that double treated cells exhibit a specific 10-gene signature associated with Erk/MAPK signaling. We hypothesized that IR-induced MAPK activation primes non-malignant HMEC to undergo TGF{beta}-mediated EMT. Consistent with this, Erk phosphorylation were transiently induced by irradiation, persisted in irradiated cells treated with TGF{beta}, and treatment with U0126, a Mek inhibitor, blocked the EMT phenotype. Together, these data demonstrate that the interactions between radiation-induced signaling pathways elicit heritable phenotypes that could contribute to neoplastic progression.

  3. Theoretical aspects of double beta decay

    International Nuclear Information System (INIS)

    Haxton, W.C.

    1984-01-01

    Considerable effort has been expended recently in theoretical studies of double beta decay. Much of this work has focussed on the constraints this process places on gauge theories of the weak interaction, in general, and on the neutrino mass matrix, in particular. In addition, interesting nuclear structure questions have arisen in studies of double beta decay matrix elements. After briefly reviewing the theory of double beta decay, some of the progress that has been made in these areas is summarized. 25 references

  4. High beta plasmas in the PBX tokamak

    International Nuclear Information System (INIS)

    Bol, K.; Buchenauer, D.; Chance, M.

    1986-04-01

    Bean-shaped configurations favorable for high β discharges have been investigated in the Princeton Beta Experiment (PBX) tokamak. Strongly indented bean-shaped plasmas have been successfully formed, and beta values of over 5% have been obtained with 5 MW of injected neutral beam power. These high beta discharges still lie in the first stability regime for ballooning modes, and MHD stability analysis implicates the external kink as responsible for the present β limit

  5. Spontaneous quaternary and tertiary T-R transitions of human hemoglobin in molecular dynamics simulation.

    Directory of Open Access Journals (Sweden)

    Jochen S Hub

    2010-05-01

    Full Text Available We present molecular dynamics simulations of unliganded human hemoglobin (Hb A under physiological conditions, starting from the R, R2, and T state. The simulations were carried out with protonated and deprotonated HC3 histidines His(beta146, and they sum up to a total length of 5.6 micros. We observe spontaneous and reproducible T-->R quaternary transitions of the Hb tetramer and tertiary transitions of the alpha and beta subunits, as detected from principal component projections, from an RMSD measure, and from rigid body rotation analysis. The simulations reveal a marked asymmetry between the alpha and beta subunits. Using the mutual information as correlation measure, we find that the beta subunits are substantially more strongly linked to the quaternary transition than the alpha subunits. In addition, the tertiary populations of the alpha and beta subunits differ substantially, with the beta subunits showing a tendency towards R, and the alpha subunits showing a tendency towards T. Based on the simulation results, we present a transition pathway for coupled quaternary and tertiary transitions between the R and T conformations of Hb.

  6. An investigation of proton pair correlations relevant to the neutrinoless double beta decay of 76Ge

    Science.gov (United States)

    Ticehurst, David R.

    The observation of neutrinoless double beta decay (0nubetabeta ) would demonstrate that the neutrino is a Majorana particle and allow determination of its mass by comparing the measured decay rate to the calculated rate. The main uncertainty in the calculation of the 0 nubetabeta rate is due to uncertainties in the nuclear structure models used in the computation of the nuclear matrix elements for the decay process. This project tested the validity of using wavefunctions for the nuclear states involved in the 0nubetabeta process that are based on a first-order application of the Bardeen-Cooper-Schrieffer (BCS) theory of superconductivity. In the BCS approximation, most of the strength for two-nucleon transfer reactions should be for transitions to the 0 + ground state of the final nucleus (i.e., little strength should go to the 0+ excited states). This experiment measured the strength to the first 0+ excited state for the 74Ge( 3He,n)76Se and 76Ge( 3He,n)78Se reactions relative to the strength for transition to the 0+ ground state in selenium. For both nuclei, and at 3He beam energies of 15 and 21 MeV, the observed relative strength for transfer to the first 0+ excited state was less than 13%. This result supports the validity of using the BCS approximation to describe the ground state of both 76Se and 78Se and is consistent with the results of recent ( 3He,n) cross section measurements on 74Ge and 76Ge. In addition, the magnitude and shape of the measured angular distributions suggest that contribution of the sequential two-nucleon transfer process, which is an indicator of long-range nucleon-nucleon correlations, is over-predicted by the DWBA code FRESCO.

  7. Incorporating beta-turns and a turn mimetic out of context in loop 1 of the WW domain affords cooperatively folded beta-sheets.

    Science.gov (United States)

    Kaul, R; Angeles, A R; Jäger, M; Powers, E T; Kelly, J W

    2001-06-06

    To probe the conformational requirements of loop 1 in the Pin1 WW domain, the residues at the i + 2 and i + 3 positions of a beta-turn within this loop were replaced by dPro-Gly and Asn-Gly, which are known to prefer the conformations required at the i + 1 and i + 2 positions of type II' and type I' beta-turns. Conformational specificity or lack thereof was further examined by incorporating into the i + 2 and i + 3 positions a non-alpha-amino acid-based beta-turn mimetic (4-(2'-aminoethyl)-6-dibenzofuran propionic acid residue, 1), which was designed to replace the i + 1 and i + 2 positions of beta-turns. All these Pin WW variants are monomeric and folded as discerned by analytical ultracentrifugation, NMR, and CD. They exhibit cooperative two-state transitions and display thermodynamic stability within 0.5 kcal/mol of the wild-type WW domain, demonstrating that the acquisition of native structure and stability does not require a specific sequence and, by extension, conformation within loop 1. However, it could be that these loop 1 mutations alter the kinetics of antiparallel beta-sheet folding, which will be addressed by subsequent kinetic studies.

  8. Earthquake Early Warning Beta Users: Java, Modeling, and Mobile Apps

    Science.gov (United States)

    Strauss, J. A.; Vinci, M.; Steele, W. P.; Allen, R. M.; Hellweg, M.

    2014-12-01

    Earthquake Early Warning (EEW) is a system that can provide a few to tens of seconds warning prior to ground shaking at a user's location. The goal and purpose of such a system is to reduce, or minimize, the damage, costs, and casualties resulting from an earthquake. A demonstration earthquake early warning system (ShakeAlert) is undergoing testing in the United States by the UC Berkeley Seismological Laboratory, Caltech, ETH Zurich, University of Washington, the USGS, and beta users in California and the Pacific Northwest. The beta users receive earthquake information very rapidly in real-time and are providing feedback on their experiences of performance and potential uses within their organization. Beta user interactions allow the ShakeAlert team to discern: which alert delivery options are most effective, what changes would make the UserDisplay more useful in a pre-disaster situation, and most importantly, what actions users plan to take for various scenarios. Actions could include: personal safety approaches, such as drop cover, and hold on; automated processes and procedures, such as opening elevator or fire stations doors; or situational awareness. Users are beginning to determine which policy and technological changes may need to be enacted, and funding requirements to implement their automated controls. The use of models and mobile apps are beginning to augment the basic Java desktop applet. Modeling allows beta users to test their early warning responses against various scenarios without having to wait for a real event. Mobile apps are also changing the possible response landscape, providing other avenues for people to receive information. All of these combine to improve business continuity and resiliency.

  9. Phase transitions in light nuclei

    International Nuclear Information System (INIS)

    Dukelsky, J.; Poves, A.; Retamosa, J.

    1991-01-01

    The SU(3) Elliott model is used to study the thermal description of 20 Ne. This solvable model allows us to work in the canonical ensemble and still be able to define an order parameter, the expectation value of the intrinsic quadrupole moment, to investigate the occurrence of phase transitions

  10. Monitor for alpha beta contamination of hands; Moniteur de contamination alpha beta des mains

    Energy Technology Data Exchange (ETDEWEB)

    Guitton, J

    1958-07-01

    The following specifications of hands alpha beta contamination monitor are presented: the position of the hands, the detection and separation of alpha and beta, the information processing, the programming, the results presentation and general characteristics. (A.L.B.)

  11. Sawtooth crashes at high beta on JET

    Energy Technology Data Exchange (ETDEWEB)

    Alper, B; Huysmans, G T.A.; Sips, A C.C. [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking; Nave, M F.F. [Universidade Tecnica, Lisbon (Portugal). Inst. Superior Tecnico

    1994-07-01

    The sawtooth crashes on JET display features which depend on beta. The main observation is a transient bulging of flux surfaces (duration inferior to 30 microsec.), which is predominantly on the low field side and extends to larger radii as beta increases. This phenomenon reaches the plasma boundary when beta{sub N} exceeds 0.5 and in these cases is followed by an ELM within 50 microsec. These sawtooth/ELM events limit plasma performance. Modelling of mode coupling shows qualitative agreement between observations of the structure of the sawtooth precursor and the calculated internal kink mode at high beta. (authors). 6 refs., 5 figs.

  12. MOPITT Beta Level 1 Radiances V107

    Data.gov (United States)

    National Aeronautics and Space Administration — The MOPITT Beta Level 1 data product consists of the geolocated, calibrated earth scene radiances, associated instrument engineering data summaries, and inflight...

  13. Fabrication of beta particles detector for RMS

    International Nuclear Information System (INIS)

    Lee, W. G.; Kim, Y. G.; Kim, J. B.; Jeong, J. E.; Hong, S. B.

    2003-01-01

    The beta particles detector for RMS (radiation monitoring system) was fabricated to detect charged beta particles. The plastic scintillator was cutted, shaped, polished to make plastic disk for beta particles. The diameter of completed plastic scintillator disk is 40 mm and thickness is 1.5 mm. The mylar film and aluminium foil were used the front of plastic scintillator to intercept light and moisture. The completed plastic detector for RMS consist of the discriminator and counter were made by ULS (Co.). The absolute efficiency of plastic detector was 45.51% for beta particles (Sr/Y - 90)

  14. Random matrix theory for transition strengths: Applications and open questions

    Science.gov (United States)

    Kota, V. K. B.

    2017-12-01

    Embedded random matrix ensembles are generic models for describing statistical properties of finite isolated interacting quantum many-particle systems. A finite quantum system, induced by a transition operator, makes transitions from its states to the states of the same system or to those of another system. Examples are electromagnetic transitions (then the initial and final systems are same), nuclear beta and double beta decay (then the initial and final systems are different) and so on. Using embedded ensembles (EE), there are efforts to derive a good statistical theory for transition strengths. With m fermions (or bosons) in N mean-field single particle levels and interacting via two-body forces, we have with GOE embedding, the so called EGOE(1+2). Now, the transition strength density (transition strength multiplied by the density of states at the initial and final energies) is a convolution of the density generated by the mean-field one-body part with a bivariate spreading function due to the two-body interaction. Using the embedding U(N) algebra, it is established, for a variety of transition operators, that the spreading function, for sufficiently strong interactions, is close to a bivariate Gaussian. Also, as the interaction strength increases, the spreading function exhibits a transition from bivariate Breit-Wigner to bivariate Gaussian form. In appropriate limits, this EE theory reduces to the polynomial theory of Draayer, French and Wong on one hand and to the theory due to Flambaum and Izrailev for one-body transition operators on the other. Using spin-cutoff factors for projecting angular momentum, the theory is applied to nuclear matrix elements for neutrinoless double beta decay (NDBD). In this paper we will describe: (i) various developments in the EE theory for transition strengths; (ii) results for nuclear matrix elements for 130Te and 136Xe NDBD; (iii) important open questions in the current form of the EE theory.

  15. M1 transitions in the (sdg) boson model

    Energy Technology Data Exchange (ETDEWEB)

    Kuyucak, S.; Morrison, I.

    1988-03-03

    Using the 1/N expansion technique we derive expressions for ..beta.. -> g, ..gamma.. -> g and ..gamma.. -> ..gamma.. M1 transitions in a general boson model. The M1 matrix elements in the sdg-boson model are similar in form to those in the neutron-proton IBM. Comparisons are made to some selected M1 data exhibiting collective character.

  16. Neutrinoless Double Beta Decay Experiments

    International Nuclear Information System (INIS)

    Garfagnini, A.

    2014-08-01

    Neutrinoless double beta decay is the only process known so far able to test the neutrino intrinsic nature: its experimental observation would imply that the lepton number is violated by two units and prove that neutrinos have a Majorana mass components, being their own anti-particle. While several experiments searching for such a rare decay have been per- formed in the past, a new generation of experiments using different isotopes and techniques have recently released their results or are taking data and will provide new limits, should no signal be observed, in the next few years to come. The present contribution reviews the latest public results on double beta decay searches and gives an overview on the expected sensitivities of the experiments in construction which will be able to set stronger limits in the near future. EXO and KamLAND-Zen experiments are based on the decay of Xe 136 , GERDA and MAJORANA experiments are based on the decay of Ge 76 , and the CUORE experiment is based on the decay of Te 130

  17. Beta attenuation transmission system (BATS)

    Energy Technology Data Exchange (ETDEWEB)

    Hagan, R.C.; Fullbright, H.J.

    1977-01-01

    The beta attenuation transmission system (BATS) is an automated radiation gauge designed for quantitative measurement of component thickness in explosive detonators. The BATS was designed and built by Group M-1, the Nondestructive Testing Group, of the Los Alamos Scientific Laboratory to measure the areal thickness, in mg/cm/sup 2/, of a cylinder of high explosive (HE) enclosed within a plastic holder. The problem is to determine the density of the HE. A /sup 90/Sr source is collimated by a 0.25 x 1.59-mm slit, and the transmitted beta-particle flux is detected by a plastic scintillator, coupled to a photomultiplier tube. The detonator is transported through the radiation beam by a leadscrew, ballnut, stepping-motor combination. Continuous analog position data are available, derived from the output from a linear-actuated potentiometer attached to the scanner. A linear electrometer amplifies the detected signal, which is then integrated for a preselected time, to obtain the desired statistical accuracy. A microprocessor (..mu..P) is used to control the scanner position and to make the data readings at the assigned positions. The data are stored, and, at the completion of the scan, are processed into the desired format. The final answer is displayed to the operator or output to a peripheral device for permanent record. The characteristics of the radiation source, the collimator, the signal detection and conditioning, and the final results are described in detail. The scanner and the microprocessor control system are briefly outlined.

  18. Beta attenuation transmission system (BATS)

    International Nuclear Information System (INIS)

    Hagan, R.C.; Fullbright, H.J.

    1977-01-01

    The beta attenuation transmission system (BATS) is an automated radiation gauge designed for quantitative measurement of component thickness in explosive detonators. The BATS was designed and built by Group M-1, the Nondestructive Testing Group, of the Los Alamos Scientific Laboratory to measure the areal thickness, in mg/cm 2 , of a cylinder of high explosive (HE) enclosed within a plastic holder. The problem is to determine the density of the HE. A 90 Sr source is collimated by a 0.25 x 1.59-mm slit, and the transmitted beta-particle flux is detected by a plastic scintillator, coupled to a photomultiplier tube. The detonator is transported through the radiation beam by a leadscrew, ballnut, stepping-motor combination. Continuous analog position data are available, derived from the output from a linear-actuated potentiometer attached to the scanner. A linear electrometer amplifies the detected signal, which is then integrated for a preselected time, to obtain the desired statistical accuracy. A microprocessor (μP) is used to control the scanner position and to make the data readings at the assigned positions. The data are stored, and, at the completion of the scan, are processed into the desired format. The final answer is displayed to the operator or output to a peripheral device for permanent record. The characteristics of the radiation source, the collimator, the signal detection and conditioning, and the final results are described in detail. The scanner and the microprocessor control system are briefly outlined

  19. Challenges in Double Beta Decay

    Directory of Open Access Journals (Sweden)

    Oliviero Cremonesi

    2014-01-01

    Full Text Available In the past ten years, neutrino oscillation experiments have provided the incontrovertible evidence that neutrinos mix and have finite masses. These results represent the strongest demonstration that the electroweak Standard Model is incomplete and that new Physics beyond it must exist. In this scenario, a unique role is played by the Neutrinoless Double Beta Decay searches which can probe lepton number conservation and investigate the Dirac/Majorana nature of the neutrinos and their absolute mass scale (hierarchy problem with unprecedented sensitivity. Today Neutrinoless Double Beta Decay faces a new era where large-scale experiments with a sensitivity approaching the so-called degenerate-hierarchy region are nearly ready to start and where the challenge for the next future is the construction of detectors characterized by a tonne-scale size and an incredibly low background. A number of new proposed projects took up this challenge. These are based either on large expansions of the present experiments or on new ideas to improve the technical performance and/or reduce the background contributions. In this paper, a review of the most relevant ongoing experiments is given. The most relevant parameters contributing to the experimental sensitivity are discussed and a critical comparison of the future projects is proposed.

  20. A practical method for in-situ thickness determination using energy distribution of beta particles

    Energy Technology Data Exchange (ETDEWEB)

    Yalcin, S., E-mail: syalcin@kastamonu.edu.tr [Kastamonu University, Education Faculty, 37200 Kastamonu (Turkey); Gurler, O. [Physics Department, Faculty of Arts and Sciences, Uludag University, Gorukle Campus, 16059 Bursa (Turkey); Gundogdu, O. [Kocaeli University, Umuttepe Campus, 41380 Kocaeli (Turkey); Bradley, D.A. [CNRP, Department of Physics, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford GU2 7XH (United Kingdom)

    2012-01-15

    This paper discusses a method to determine the thickness of an absorber using the energy distribution of beta particles. An empirical relationship was obtained between the absorber thickness and the energy distribution of beta particles transmitted through. The thickness of a polyethylene radioactive source cover was determined by exploiting this relationship, which has largely been left unexploited allowing us to determine the in-situ cover thickness of beta sources in a fast, cheap and non-destructive way. - Highlights: Black-Right-Pointing-Pointer A practical and in-situ unknown cover thickness determination Black-Right-Pointing-Pointer Cheap and readily available compared to other techniques. Black-Right-Pointing-Pointer Beta energy spectrum.

  1. Energy transition

    International Nuclear Information System (INIS)

    Anon.

    2013-01-01

    The yearly environmental conference will hold on September 2013 to evaluate the negotiations led at the national and local levels for december 2012. The government will have then to decide of an energy programming bill which will be submitted to the Parliament at the beginning of the year 2014. 30 main propositions have emerged of the decentralised debates. One of them is the ecological taxation which raise the question of the gas oil and petrol taxation. The current environmental taxes are for almost three quarters of them taxes on energy consumptions and mainly on fossil energies. The Economic, Social and Environmental Council, gives his opinion on the way to find resources to ensure the ecological and energy transition while reducing the public deficit of the State. (O.M.)

  2. Natural polypeptide scaffolds: beta-sheets, beta-turns, and beta-hairpins.

    Science.gov (United States)

    Rotondi, Kenneth S; Gierasch, Lila M

    2006-01-01

    This paper provides an introduction to fundamental conformational states of polypeptides in the beta-region of phi,psi space, in which the backbone is extended near to its maximal length, and to more complex architectures in which extended segments are linked by turns and loops. There are several variants on these conformations, and they comprise versatile scaffolds for presentation of side chains and backbone amides for molecular recognition and designed catalysts. In addition, the geometry of these fundamental folds can be readily mimicked in peptidomimetics. Copyright 2005 Wiley Periodicals, Inc.

  3. TGF{beta} induces proHB-EGF shedding and EGFR transactivation through ADAM activation in gastric cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Ebi, Masahide [Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya (Japan); Kataoka, Hiromi, E-mail: hkataoka@med.nagoya-cu.ac.jp [Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya (Japan); Shimura, Takaya; Kubota, Eiji; Hirata, Yoshikazu; Mizushima, Takashi; Mizoshita, Tsutomu; Tanaka, Mamoru; Mabuchi, Motoshi; Tsukamoto, Hironobu; Tanida, Satoshi; Kamiya, Takeshi [Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya (Japan); Higashiyama, Shigeki [Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine, Ehime (Japan); Joh, Takashi [Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya (Japan)

    2010-11-19

    Research highlights: {yields} TGF{beta} induces EGFR transactivation through proHB-EGF shedding by activated ADAM members in gastric cancer cells. {yields} TGF{beta} induces nuclear translocation of HB-EGF-CTF cleaved by ADAM members. {yields} TGF{beta} enhances cell growth by EGFR transactivation and HB-EGF-CTF nuclear translocation and ADAM inhibitors block these effects. {yields} Silencing of ADAM17 also blocks EGFR transactivation, HB-EGF-CTF nuclear translocation and cancer cell growth by TGF{beta}. {yields} ADAM17 may play a crucial role in this TGF{beta}-HB-EGF signal transduction. -- Abstract: Background and aims: Transforming growth factor-beta (TGF{beta}) is known to potently inhibit cell growth. Loss of responsiveness to TGF{beta} inhibition on cell growth is a hallmark of many types of cancer, yet its mechanism is not fully understood. Membrane-anchored heparin-binding EGF-like growth factor (proHB-EGF) ectodomain is cleaved by a disintegrin and metalloproteinase (ADAM) members and is implicated in epidermal growth factor receptor (EGFR) transactivation. Recently, nuclear translocation of the C-terminal fragment (CTF) of pro-HB-EGF was found to induce cell growth. We investigated the association between TGF{beta} and HB-EGF signal transduction via ADAM activation. Materials and methods: The CCK-8 assay in two gastric cancer cell lines was used to determine the effect for cell growth by TGF{beta}. The effect of two ADAM inhibitors was also evaluated. Induction of EGFR phosphorylation by TGF{beta} was analyzed and the effect of the ADAM inhibitors was also examined. Nuclear translocation of HB-EGF-CTF by shedding through ADAM activated by TGF{beta} was also analyzed. EGFR transactivation, HB-EGF-CTF nuclear translocation, and cell growth were examined under the condition of ADAM17 knockdown. Result: TGF{beta}-induced EGFR phosphorylation of which ADAM inhibitors were able to inhibit. TGF{beta} induced shedding of proHB-EGF allowing HB-EGF-CTF to

  4. Complement activation by the amyloid proteins A beta peptide and beta 2-microglobulin

    DEFF Research Database (Denmark)

    Nybo, Mads; Nielsen, E H; Svehag, S E

    1999-01-01

    component nor heparan sulfate did significantly alter the A beta-induced CA. The results indicate that not only fibrillar A beta but also oligomers of, in particular, beta 2M from patients with dialysis-associated amyloidosis are capable of inducing CA at supra-physiological concentrations....

  5. Characterisation and confirmation of rare beta-thalassaemia mutations in the Malay, Chinese and Indian ethnic groups in Malaysia.

    Science.gov (United States)

    Tan, Jin Ai Mary Anne; Chin, Pui See; Wong, Yean Ching; Tan, Kim Lian; Chan, Lee Lee; George, Elizabeth

    2006-10-01

    In Malaysia, about 4.5% of the Malay and Chinese populations are heterozygous carriers of beta-thalassaemia. The initial identification of rare beta-globin gene mutations by genomic sequencing will allow the development of simpler and cost-effective PCR-based techniques to complement the existing amplification refractory mutation system (ARMS) and gap-PCR used for the identification of beta-thalassaemia mutations. DNA from 173 beta-thalassaemia carriers and five beta-thalassaemia major patients from the Malay, Chinese and Indian ethnic groups were first analysed by ARMS and gap-PCR. Ninety-five per cent (174/183) of the 183 beta-globin genes studied were characterised using these two techiques. The remaining nine uncharacterised beta-globin genes (4.9%) were analysed using genomic sequencing of a 904 bp amplified PCR product consisting of the promoter region, exon 1, intervening sequence (IVS) 1, exon 2 and the 5' IVS2 regions of the beta-globin gene. The rare beta-globin mutations detected in the Chinese patients were CD27/28 (+C) and CD43 (GAG-TAG), and -88 (C-T) in an Indian patient. Beta-globin mutations at CD16 (-C), IVS1-1 (G-A), IVS2-1 (G-A), -86 (C-G) and Haemoglobin South Florida (CD1, GTG-ATG) were confirmed in the Malay patients. The seven rare beta-globin mutations and a rare haemoglobin variant confirmed in this study have been described in other populations but have not been previously described in Malaysian beta-thalassemia patients.

  6. Phase transition in the hadron gas model

    International Nuclear Information System (INIS)

    Gorenstein, M.I.; Petrov, V.K.; Zinov'ev, G.M.

    1981-01-01

    A class of statistical models of hadron gas allowing an analytical solution is considered. A mechanism of a possible phase transition in such a system is found and conditions for its occurence are determined [ru

  7. Cloning and characterization of human liver cytosolic beta-glycosidase

    NARCIS (Netherlands)

    De Graaf, M; Van Veen, IC; Van Der Meulen-Muileman, IH; Gerritsen, WR; Pinedo, HM; Haisma, HJ

    2001-01-01

    Cytosolic beta -glucosidase (EC 3.2.1.21) from mammalian liver is a member of the family 1 glycoside hydrolases and is known for its ability to hydrolyse a range of beta -D-glycosides. including beta -D-glucoside acid beta -D-galactoside. We therefore refer to this enzyme as cytosolic beta

  8. Beta-glucosidase variants and polynucleotides encoding same

    Science.gov (United States)

    Wogulis, Mark; Harris, Paul; Osborn, David

    2017-06-27

    The present invention relates to beta-glucosidase variants, e.g. beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus. The present invention also relates to polynucleotides encoding the beta-glucosidase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the beta-glucosidase variants.

  9. The Role of Transitions in ESL Instruction

    Science.gov (United States)

    Steinman, Linda

    2013-01-01

    Transitions in ESL contexts generally refer to those linking words placed between sentences and between paragraphs. Transitions in writing (and in speaking) are helpful; they facilitate coherence and cohesion when used correctly. Understanding them when reading allows us to join the writer in seeing why and how idea B follows idea A. In this…

  10. Preventive Effects of Beta-Hydroxy-Beta-Methyl Butyrate

    Directory of Open Access Journals (Sweden)

    N. Ravanbakhsh

    2016-09-01

    Full Text Available Aims: One of the major factors in sudden cardiac arrest is the initiation and continuation of deadly arrhythmias during ischemia. It is known that beta-hydroxy-beta-methylbutyrate (HMB has useful effects such as anti-inflammatory and anti-apoptosis effects in the skeletal muscles. The aim of this study was to investigate the preventive effects of HMB on the ventricular arrhythmias due to the ischemia. Materials & Methods: In the experimental study, 30 Wistar male rats were randomly divided into three groups including control, HMB320, and HMB700. As control group received normal saline, HMB320 and HMB700 groups orally received 320 and 700 mg/Kg HMB as gavage for 2 weeks, respectively. The rats, having been anesthetized, underwent 30-minute ischemia. Then, the numbers of premature ventricular contractions (PVC, the appearance duration of ventricular tachycardia (VT, and the ventricular fibrillation (VF were assessed. Data was analyzed by SPSS 16 software using Kruskal-Walis, one-way ANOVA, Tukey’s post-hoc, and Chi-square tests. Findings: There was a significant reduction in the mean PVC number in HMB320 and HMB700 groups than control group (p=0.001. In addition, there was such a significant difference between the groups received the doses (p=0.008. There was a reduction in the mean appearance duration of VT in HMB320 and HMB700 groups than control group (p=0.001. There was a significant reduction in the mean appearance duration of VF in HMB700 group compared to control group, only (p=0.003. Conclusion: Through arrhythmias reduction, 2-week preventive consumption of HMB might considerably reduce the severe side effects of ischemia.

  11. Expression of transforming growth factor beta (TGF beta) receptors and expression of TGF beta 1, TGF beta 2 and TGF beta 3 in human small cell lung cancer cell lines

    DEFF Research Database (Denmark)

    Damstrup, L; Rygaard, K; Spang-Thomsen, M

    1993-01-01

    A panel of 21 small cell lung cancer cell (SCLC) lines were examined for the presence of Transforming growth factor beta receptors (TGF beta-r) and the expression of TGF beta mRNAs. By the radioreceptor assay we found high affinity receptors to be expressed in six cell lines. scatchard analysis......(r) = 65,000 and 90,000 and the betaglycan (type III) with M(r) = 280,000. Northern blotting showed expression of TGF beta 1 mRNA in ten, TGF beta 2 mRNA in two and TGF beta 3 mRNA in seven cell lines. Our results provide, for the first time, evidence that a large proportion of a broad panel of SCLC cell...... lines express TGF beta-receptors and also produce TGF beta mRNAs....

  12. Beta Testing StraboSpot: Perspectives on mobile field mapping and data collection

    Science.gov (United States)

    Bunse, E.; Graham, K. A.; Rufledt, C.; Walker, J. D.; Müller, A.; Tikoff, B.

    2017-12-01

    Geologic field mapping has recently transitioned away from traditional techniques (e.g. field notebooks, paper mapping, Brunton compasses) and towards mobile `app' mapping technology. The StraboSpot system (Strabo) is an open-source solution for collection and storage for geologic field, microstructural, and lab-based data. Strabo's mission is to "enable recording and sharing data within the geoscience community, encourage interdisciplinary research, and facilitate the investigation of scientific questions that cannot currently be addressed" (Walker et al., 2015). Several mobile application beta tests of the system, on both Android and Apple iOS platforms using smartphones and tablets, began in Summer 2016. Students at the 2016 and 2017 University of Kansas Field Camps used Strabo in place of ArcGIS for Desktop on Panasonic Toughbooks, to field map two study areas. Strabo was also field tested by students of graduate and undergraduate level for both geo/thermochronologic sample collection and reconnaissance mapping associated with regional tectonic analysis in California. Throughout this period of testing, the app was geared toward structural and tectonic geologic data collection, but is versatile enough for other communities to currently use and is expanding to accommodate the sedimentology and petrology communities. Overall, users in each of the beta tests acclimated quickly to using Strabo for field data collection. Some key advantages to using Strabo over traditional mapping methods are: (1) Strabo allows for consolidation of materials in the field; (2) helps students track their position in the field with integrated GPS; and (3) Strabo data is in a uniform format making it simple for geologists to collaborate. While traditional field methods are not likely to go out of style in the near future, Strabo acts as a bridge between professional and novice geologists by providing a tool that is intuitive on all levels of geological and technological experience and

  13. Kondo-Anderson transitions

    Science.gov (United States)

    Kettemann, S.; Mucciolo, E. R.; Varga, I.; Slevin, K.

    2012-03-01

    Dilute magnetic impurities in a disordered Fermi liquid are considered close to the Anderson metal-insulator transition (AMIT). Critical power-law correlations between electron wave functions at different energies in the vicinity of the AMIT result in the formation of pseudogaps of the local density of states. Magnetic impurities can remain unscreened at such sites. We determine the density of the resulting free magnetic moments in the zero-temperature limit. While it is finite on the insulating side of the AMIT, it vanishes at the AMIT, and decays with a power law as function of the distance to the AMIT. Since the fluctuating spins of these free magnetic moments break the time-reversal symmetry of the conduction electrons, we find a shift of the AMIT, and the appearance of a semimetal phase. The distribution function of the Kondo temperature TK is derived at the AMIT, in the metallic phase, and in the insulator phase. This allows us to find the quantum phase diagram in an external magnetic field B and at finite temperature T. We calculate the resulting magnetic susceptibility, the specific heat, and the spin relaxation rate as a function of temperature. We find a phase diagram with finite-temperature transitions among insulator, critical semimetal, and metal phases. These new types of phase transitions are caused by the interplay between Kondo screening and Anderson localization, with the latter being shifted by the appearance of the temperature-dependent spin-flip scattering rate. Accordingly, we name them Kondo-Anderson transitions.

  14. Beta-agonists and animal welfare

    Science.gov (United States)

    The use of beta-agonists in animal feed is a high profile topic within the U.S. as consumers and activist groups continue to question its safety. The only beta-agonist currently available for use in swine is ractopamine hydrochloride (RAC). This is available as Paylean™ (Elanco Animal Health – FDA a...

  15. Beta-2-mikroglobulin ved medicinske sygdomme

    DEFF Research Database (Denmark)

    Hansen, P B; Olsen, Niels Vidiendal

    1989-01-01

    Beta-2-microglobulin (beta 2M) is a low-molecular protein which is filtered freely over the glomeruli. Under normal circumstances, more than 99.9% is resorbed in the proximal tubuli of the kidneys and is metabolized there. In renal disease with damage to this segment of the nephron, eg acute tubulo...

  16. Topical beta-blockers and mortality

    NARCIS (Netherlands)

    Müskens, Rogier P. H. M.; Wolfs, Roger C. W.; Witteman, Jacqueline C. M.; Hofman, Albert; de Jong, Paulus T. V. M.; Stricker, Bruno H. C.; Jansonius, Nomdo M.

    2008-01-01

    To study the associations between long-term and short-term use of topical beta-blockers and mortality. Prospective population-based cohort study. To examine long-term effects, 3842 participants aged 55 years and older were recruited. To examine short-term effects, 484 incident beta-blocker users and

  17. The beta subunit of casein kinase II

    DEFF Research Database (Denmark)

    Boldyreff, B; Piontek, K; Schmidt-Spaniol, I

    1991-01-01

    cDNAs encoding the beta subunit of pig and mouse CKII were isolated. The porcine cDNA was expressed as a fusion protein in Escherichia coli and used for the production of anti-CKII-beta subunit specific antibodies....

  18. Beta delayed particle emission in light nuclei

    International Nuclear Information System (INIS)

    Riisager, K.; Gabelmann, H.

    1991-01-01

    A short discussion of theoretical treatments of beta delayed particle emission is followed by a presentation of data on the newly found beta delayed deuteron decay of 6 He. This decay cannot be described properly with existing theories. (author) 8 refs.; 3 figs

  19. MINIMUM VARIANCE BETA ESTIMATION WITH DYNAMIC CONSTRAINTS,

    Science.gov (United States)

    developed (at AFETR ) and is being used to isolate the primary error sources in the beta estimation task. This computer program is additionally used to...determine what success in beta estimation can be achieved with foreseeable instrumentation accuracies. Results are included that illustrate the effects on

  20. Synthetic peptides corresponding to human follicle-stimulating hormone (hFSH)-beta-(1-15) and hFSH-beta-(51-65) induce uptake of 45Ca++ by liposomes: evidence for calcium-conducting transmembrane channel formation

    Energy Technology Data Exchange (ETDEWEB)

    Grasso, P.; Santa-Coloma, T.A.; Reichert, L.E. Jr. (Department of Biochemistry, Albany Medical College, New York, NY (USA))

    1991-06-01

    We have previously described FSH receptor-mediated influx of 45Ca++ in cultured Sertoli cells from immature rats and receptor-enriched proteoliposomes via activation of voltage-sensitive and voltage-independent calcium channels. We have further shown that this effect of FSH does not require cholera toxin- or pertussis toxin-sensitive guanine nucleotide binding protein or activation of adenylate cyclase. In the present study, we have identified regions of human FSH-beta-subunit which appear to be involved in mediating calcium influx. We screened 11 overlapping peptide amides representing the entire primary structure of hFSH-beta-subunit for their effects on 45Ca++ flux in FSH receptor-enriched proteoliposomes. hFSH-beta-(1-15) and hFSH-beta-(51-65) induced uptake of 45Ca++ in a concentration-related manner. This effect of hFSH-beta-(1-15) and hFSH-beta-(51-65) was also observed in liposomes lacking incorporated FSH receptor. Reducing membrane fluidity by incubating liposomes (containing no receptor) with hFSH-beta-(1-15) or hFSH-beta-(51-65) at temperatures lower than the transition temperatures of their constituent phospholipids resulted in no significant (P greater than 0.05) difference in 45Ca++ uptake. The effectiveness of the calcium ionophore A23187, however, was abolished. Ruthenium red, a voltage-independent calcium channel antagonist, was able to completely block uptake of 45Ca++ induced by hFSH-beta-(1-15) and hFSH-beta-(51-65) whereas nifedipine, a calcium channel blocker specific for L-type voltage-sensitive calcium channels, was without effect. These results suggest that in addition to its effect on voltage-sensitive calcium channel activity, interaction of FSH with its receptor may induce formation of transmembrane aqueous channels which also facilitate influx of extracellular calcium.

  1. Novel dense CO2 technique for beta-galactosidase immobilization in polystyrene microchannels.

    Science.gov (United States)

    Leclair Ellis, Jeffrey; Tomasko, David L; Dehghani, Fariba

    2008-03-01

    In this study we design new fabrication techniques and demonstrate the potential of using dense CO2 for facilitating crucial steps in the fabrication of polymeric lab-on-a-chip microdevices by embedding biomolecules at temperatures well below the polymer's glass transition temperature (T(g)). These new techniques are environmentally friendly and done without the use of a clean room. Carbon dioxide at 40 degrees C and between 4.48 and 6.89 MPa was used to immobilize the biologically active molecule, beta-galactosidase (beta-gal), on the surface of polystyrene microchannels. To our knowledge, this is the first time dense CO2 has been used to directly immobilize an enzyme in a microchannel. beta-gal activity was maintained and shown via a fluorescent reaction product, after enzyme immobilization and microchannel capping by the designed fabrication steps at 40 degrees C and pressures up to 6.89 MPa.

  2. Selected aspects in the structure of beta-delayed particle spectra

    International Nuclear Information System (INIS)

    Honkanen, J.; Aeystoe, J.; Eskola, K.

    1986-01-01

    Some weak beta-delayed particle emitters in the T z =-3/2, -1, -1/2, +1/2 and +5/2 series are reviewed. Selected features of the delayed particle emission are discussed in terms of experimental delayed particle data and (p,γ), (p,p') and (p,n) reaction data. Experimental beta transition strengths are compared with the existing complete shell-model calculations for the sd-shell nuclei. The effect of the Gamow-Teller giant resonance on the structure of the delayed particle spectra is considered. The correlation between the widths of two decay channels, protons and alpha particles, and the preceeding beta decay is studied in the case of the 40 Sc decay. (orig.)

  3. Purification of beta-acetylglucosaminase and beta-galactosidase from ram testis.

    Science.gov (United States)

    Caygill, J C; Roston, C P; Jevons, F R

    1966-02-01

    1. The presence of beta-galactosidase (EC 3.2.1.23) in an acetic acid extract of ram testis is reported. Some properties of the crude enzyme preparation were studied. 2. The purification of beta-acetylglucosaminase (EC 3.2.1.30) and of beta-galactosidase from the ram-testis extract by ammonium sulphate precipitation and chromatography on a CM-cellulose column is described. 3. The final purifications of the separated enzymes achieved were for the beta-acetylglucosaminase 35 times and for the beta-galactosidase 99 times. 4. The possibility of using DEAE-cellulose and Sephadex G-200 to purify the enzymes was investigated.

  4. Clusters of conserved beta cell marker genes for assessment of beta cell phenotype

    DEFF Research Database (Denmark)

    Martens, Geert A; Jiang, Lei; Hellemans, Karine H

    2011-01-01

    The aim of this study was to establish a gene expression blueprint of pancreatic beta cells conserved from rodents to humans and to evaluate its applicability to assess shifts in the beta cell differentiated state. Genome-wide mRNA expression profiles of isolated beta cells were compared to those...... of a large panel of other tissue and cell types, and transcripts with beta cell-abundant and -selective expression were identified. Iteration of this analysis in mouse, rat and human tissues generated a panel of conserved beta cell biomarkers. This panel was then used to compare isolated versus laser capture...

  5. Endovascular Irradiations with beta sources

    Energy Technology Data Exchange (ETDEWEB)

    Scmidt, W F.O.; Hawliczek, R [Inst of Radiooncology IRO, Donauspital, Vienna (Austria); Mueck, K [Austrian Research Centre, Siebersdorf ARCS (Austria); Lehmann, D [Inst of Radiotherapy, Univ. Dresden (Germany); Pichler, L [Ludwig Boltzmann Institute for Endovascular Radiotherapy, Donauspital, Vienna (Austria)

    1999-12-31

    For treatment of restenoses tubes (inner/outer diameter 1 and 2 mm; length 3 or 5 mm) with Y-90 foils, shielded by Ti-layers on all sides have been developed (activity 0.5 - 2 GBq). Quality checks with plastic scintillators have been developed and are correlated to absolute dose measurements performed with TLDs (1x1 mm2; 40 mg/cm2). TLD-handling and calibration for beta-dosimetry are described. Additional measurements for depth-dose and dose distribution around the tubes were done with GAFCHROMIC- films and compared to Monte-Carlo calculations with the MCNP4-code, yielding a half-value depth of 0.8 mm from the tube-surface. Manufacturing and delivery of the sources including leakage tests has been standardized, treatments (irradiation times <5min; irradiation length <30mm) are planned to start in spring `98. (authors) 1 refs., 5 figs.

  6. Beta decay of 22O

    International Nuclear Information System (INIS)

    Hubert, F.; Dufour, J.P.; Del Moral, R.; Fleury, A.; Jean, D.; Pravikoff, M.S.; Geissel, H.; Schmidt, K.H.; Hanelt, E.

    1989-01-01

    The study of light nuclei far from stability has been recently renewed by the possibility of production through the projectile fragmentation of intermediate energy heavy ion beams at GANIL. The results presented here have been obtained with the Projectile Fragments Isotopic Separation method developed at the LISE spectrometer. 22 O is a Tz = 3 nucleus and is the first in a series of seven such nuclei in the sd shell extending from 22 O to 24 Mg. Although the half life of 22 O was previously measured by Murphy et al., the present study is the first beta-gamma spectroscopy on this neutron rich nucleus. Five gamma lines have been attributed to the β decay of 22 O with a measured half life of T = (2.25±0.15)s and a partial decay scheme has been established

  7. PBX: the Princeton beta experiment

    International Nuclear Information System (INIS)

    Bol, K.; Chance, M.; Dewar, R.

    1983-09-01

    A rearrangement of the divertor coils in PDX will enable a test in 1984 of the MHD stability properties of deeply indented bean-shaped plasmas. The goal is a beta of 10%. Indentation is expected to counter the deterioration of MHD stability against pressure driven modes that is occasioned by the larger aspect ratios typical of anticipated reactor oriented devices. Indeed, as shown by M. Chance et al., indentation may offer direct access to the second region of stability for ballooning modes, and numerical analyses with PEST show the internal kink to be stabilized completely with even relatively modest indentation. The internal kink is implicated in the loss of beam ions in PDX. In this report the theoretical basis for the forthcoming experiment, and the design considerations underlying the modification from PDX to PBX, are described in detail. Additional theoretical material, including an analysis of particle orbits in an indented tokamak plasma, is appended

  8. Formation of a stable oligomer of beta-2 microglobulin requires only transient encounter with Cu(II).

    Science.gov (United States)

    Calabrese, Matthew F; Miranker, Andrew D

    2007-03-16

    Beta-2 Microglobulin (beta2m) is a small, globular protein, with high solubility under conditions comparable to human serum. A complication of hemodialysis in renal failure patients is the deposition of unmodified beta2m as amyloid fibers. In vitro, exposure of beta2m to equimolar Cu(2+) under near-physiological conditions can result in self-association leading to amyloid fiber formation. Previously, we have shown that the early steps in this process involve a catalyzed structural rearrangement followed by formation of discrete oligomers. These oligomers, however, have a continued requirement for Cu(2+) while mature fibers are resistant to addition of metal chelate. Here, we report that the transition from Cu(2+) dependent to chelate resistant states occurs in the context of small oligomers, dimeric to hexameric in size. These species require Cu(2+) to form, but once generated, do not need metal cation for stability. Importantly, this transition occurs gradually over several days and the resulting oligomers are isolatable and kinetically stable on timescales exceeding weeks. In addition, formation is enhanced by levels of urea similar to those found in hemodialysis patients. Our results are consistent with our hypothesis that transient encounter of full-length wild-type beta2m with transition metal cation at the dialysis membrane interface is causal to dialysis related amyloidosis.

  9. Localization of thymosin beta-4 in tumors

    DEFF Research Database (Denmark)

    Larsson, L. -I.; Holck, Susanne

    2007-01-01

    in colorectal carcinomas. The degree of staining of breast cancer cells for thymosin beta-4 correlated neither to histological grade nor to endothelial cell staining. However, there was a tendency toward correlation (P = 0.07) between staining of endothelial cells and histological grade. Treatment of cultured......Overexpression of thymosin beta-4 has been linked to malignant progression but the localization of this polypeptide within tumors is incompletely known. We therefore examined breast cancers for thymosin beta-4 using immunofluorescence. Reactive cells were identified with monoclonal cell marker...... breast cancer cells (SK-BR-3) with 1-4 microg thymosin beta-4/mL significantly increased cell numbers, as determined by MTT-assays. These data reveal an unexpected cellular heterogeneity of thymosin beta-4 expression in breast and colonic carcinomas and suggest that local release of this polypeptide...

  10. Ranking beta sheet topologies of proteins

    DEFF Research Database (Denmark)

    Fonseca, Rasmus; Helles, Glennie; Winter, Pawel

    2010-01-01

    One of the challenges of protein structure prediction is to identify long-range interactions between amino acids. To reliably predict such interactions, we enumerate, score and rank all beta-topologies (partitions of beta-strands into sheets, orderings of strands within sheets and orientations...... of paired strands) of a given protein. We show that the beta-topology corresponding to the native structure is, with high probability, among the top-ranked. Since full enumeration is very time-consuming, we also suggest a method to deal with proteins with many beta-strands. The results reported...... in this paper are highly relevant for ab initio protein structure prediction methods based on decoy generation. The top-ranked beta-topologies can be used to find initial conformations from which conformational searches can be started. They can also be used to filter decoys by removing those with poorly...

  11. 49 CFR 230.24 - Maximum allowable stress.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Maximum allowable stress. 230.24 Section 230.24... Allowable Stress § 230.24 Maximum allowable stress. (a) Maximum allowable stress value. The maximum allowable stress value on any component of a steam locomotive boiler shall not exceed 1/4 of the ultimate...

  12. Maternal plasma concentrations of beta-lipotrophin, beta-endorphin and gamma-lipotrophin throughout pregnancy.

    Science.gov (United States)

    Browning, A J; Butt, W R; Lynch, S S; Shakespear, R A

    1983-12-01

    Plasma beta-LPH, beta-EP and gamma-LPH concentrations were measured by radioimmunoassay in 10 pregnant women from 12 weeks gestation until term and in nine women in the early follicular phase of the cycle. There was a progressive and significant rise in the concentration of all three peptides throughout pregnancy and by 32 weeks the concentrations of beta-LPH and beta-EP were greater than the corresponding concentrations in the follicular phase: gamma-LPH was greater than in the follicular phase by the end of pregnancy in those women who were delivered after 40 weeks. The ratio of beta-LPH to gamma-LPH did not change significantly throughout pregnancy, but there was a progressive fall in the beta-LPH/beta-EP ratio. The possible presence of a 'big LPH' to explain this finding is discussed.

  13. Clusters of conserved beta cell marker genes for assessment of beta cell phenotype

    DEFF Research Database (Denmark)

    Martens, Geert A; Jiang, Lei; Hellemans, Karine H

    2011-01-01

    The aim of this study was to establish a gene expression blueprint of pancreatic beta cells conserved from rodents to humans and to evaluate its applicability to assess shifts in the beta cell differentiated state. Genome-wide mRNA expression profiles of isolated beta cells were compared to those...... of a large panel of other tissue and cell types, and transcripts with beta cell-abundant and -selective expression were identified. Iteration of this analysis in mouse, rat and human tissues generated a panel of conserved beta cell biomarkers. This panel was then used to compare isolated versus laser capture...... microdissected beta cells, monitor adaptations of the beta cell phenotype to fasting, and retrieve possible conserved transcriptional regulators....

  14. Decay Spectroscopy for Nuclear Astrophysics: {beta}-delayed Proton Decay

    Energy Technology Data Exchange (ETDEWEB)

    Trache, L.; Simmons, E.; Spiridon, A.; McCleskey, M.; Roeder, B. T.; Tribble, R. E. [Texas A and M University, College Station, TX 77845 (United States); Saastamoinen, A.; Jokinen, A.; Aysto, J. [University of Jyvaskyla, Jyvaskyla (Finland); Davinson, T.; Woods, P. J. [University of Edinburgh, Edinburgh (United Kingdom); Pollacco, E.; Kebbiri, M. [CEA/IRFU Saclay (France); Pascovici, G. [IKP, Universitaet zu Koeln (Germany)

    2011-11-30

    Decay spectroscopy is one of the oldest indirect methods in nuclear astrophysics. We have developed at TAMU techniques to measure beta- and beta-delayed proton decay of sd-shell, proton-rich nuclei. The short-lived radioactive species are produced in-flight, separated, then slowed down (from about 40 MeV/u) and implanted in the middle of very thin Si detectors. These allowed us to measure protons with energies as low as 200 keV from nuclei with lifetimes of 100 ms or less. At the same time we measure gamma-rays up to 8 MeV with high resolution HPGe detectors. We have studied the decay of {sup 23}Al, {sup 27}P, {sup 31}Cl, all important for understanding explosive H-burning in novae. The technique has shown a remarkable selectivity to beta-delayed charged-particle emission and works even at radioactive beam rates of a few pps. The states populated are resonances for the radiative proton capture reactions {sup 22}Na(p,{gamma}){sup 23}Mg(crucial for the depletion of {sup 22}Na in novae), {sup 26m}Al(p,{gamma}){sup 27}Si and {sup 30}P(p,{gamma}){sup 31}S(bottleneck in novae and XRB burning), respectively. More recently we have radically improved the technique using a gas based detector we call AstroBox.

  15. State-of-the-Art Beta Detection and Dosimetry

    International Nuclear Information System (INIS)

    David M. Hamby

    2008-01-01

    The research funded by this NEER grant establishes the framework for a detailed understanding of the challenges in beta dosimetry, especially in the presence of a mixed radiation field. The work also stimulated the thinking of the research group which will lead to new concepts in digital signal processing to allow collection of detection signals and real-time analysis such that simultaneous beta and gamma spectroscopy can take place. The work described herein (with detail in the many publications that came out of this research) was conducted in a manner that provided dissertation and thesis topics for three students, one of whom was completely funded by this grant. The overall benefit of the work came in the form of a dramatic shift in signal processing that is normally conducted in analog pulse shape analysis. Analog signal processing was shown not to be feasible for this type of work; digital signal processing was a must. This, in turn, led the research team to a new understanding of pulse analysis, one in which expands the state-of-the-art in simultaneous beta and gamma spectroscopy with a single detector

  16. State-of-the-Art Beta Detection and Dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    David M. Hamby

    2008-08-15

    The research funded by this NEER grant establishes the framework for a detailed understanding of the challenges in beta dosimetry, especially in the presence of a mixed radiation field. The work also stimulated the thinking of the research group which will lead to new concepts in digital signal processing to allow collection of detection signals and real-time analysis such that simultaneous beta and gamma spectroscopy can take place. The work described herein (with detail in the many publications that came out of this research) was conducted in a manner that provided dissertation and thesis topics for three students, one of whom was completely funded by this grant. The overall benefit of the work came in the form of a dramatic shift in signal processing that is normally conducted in analog pulse shape analysis. Analog signal processing was shown not to be feasible for this type of work; digital signal processing was a must. This, in turn, led the research team to a new understanding of pulse analysis, one in which expands the state-of-the-art in simultaneous beta and gamma spectroscopy with a single detector.

  17. Dose point kernels for beta-emitting radioisotopes

    International Nuclear Information System (INIS)

    Prestwich, W.V.; Chan, L.B.; Kwok, C.S.; Wilson, B.

    1986-01-01

    Knowledge of the dose point kernel corresponding to a specific radionuclide is required to calculate the spatial dose distribution produced in a homogeneous medium by a distributed source. Dose point kernels for commonly used radionuclides have been calculated previously using as a basis monoenergetic dose point kernels derived by numerical integration of a model transport equation. The treatment neglects fluctuations in energy deposition, an effect which has been later incorporated in dose point kernels calculated using Monte Carlo methods. This work describes new calculations of dose point kernels using the Monte Carlo results as a basis. An analytic representation of the monoenergetic dose point kernels has been developed. This provides a convenient method both for calculating the dose point kernel associated with a given beta spectrum and for incorporating the effect of internal conversion. An algebraic expression for allowed beta spectra has been accomplished through an extension of the Bethe-Bacher approximation, and tested against the exact expression. Simplified expression for first-forbidden shape factors have also been developed. A comparison of the calculated dose point kernel for 32 P with experimental data indicates good agreement with a significant improvement over the earlier results in this respect. An analytic representation of the dose point kernel associated with the spectrum of a single beta group has been formulated. 9 references, 16 figures, 3 tables

  18. Dosimetry of beta sources utilized in nuclear medicine and biomedicine

    International Nuclear Information System (INIS)

    Bergoc, R.M.; Rivera, E.; Cricco, G.; Martin, G.; Cocca, C.; Caro, R.A.

    1998-01-01

    Full text: The use of high energy pure beta sources (i.e., 32 P= 1.71 MeV/des) is common in medicine (intratumoral therapy or treatment of non-malignant illness as restenosis) and in biochemistry (molecular biology). The external dosimetry of these sources offers some important points that must be considered: 1) beta particles emitted by the source are not monoenergetic; 2) the range (R 0 ) vary with the source energy and the Z of the absorber; 3) below an energy of 1 MeV, the specific ionization in the absorbent medium (air, water, lucite) increases as the beta energy (E β ) decreases; 4) the range of beta particles, R β , is independent from Z of the material, provided Z is low and the material has no hydrogen; in this case, the expression: R β δ 1 = R β δ 2 is valid; 5) the calculation of the external beta dosimetry must consider that since the used sources are not punctual there is self-absorption which should be taken into account. However, in the range of the fractions of activities for the above mentioned practices a theoretical model for punctual sources can be used; in this case, it is valid to use the expression: Dose Rate: = A (S/δ)E β e -S/δ δx /4 π d 2 , where: (S/δ) is the absorbent Mass Stopping Power and represents the loss of energy by unit mass thickness; it depends from E β and it is independent from Z; (δx) is the mass thickness of the absorber. By this way, e -S/δ δx is the attenuation of the beta particles flow. From the application of this formula it can be deduced that, for sources of 1 mCi of 32 P activities, as those employed in biochemistry, a small thickness of lucite is enough shield. When the source has higher activities, as those used in radiotherapy, the operator should take into account the regulations for a strict dosimetric control. These formulae allow a simplified calculation of the 32 P dosimetry of sources used in nuclear medicine and biomedical practices. (author) [es

  19. Dimers of beta 2-glycoprotein I mimic the in vitro effects of beta 2-glycoprotein I-anti-beta 2-glycoprotein I antibody complexes

    NARCIS (Netherlands)

    Lutters, B. C.; Meijers, J. C.; Derksen, R. H.; Arnout, J.; de Groot, P. G.

    2001-01-01

    Anti-beta(2)-glycoprotein I antibodies are thought to cause lupus anticoagulant activity by forming bivalent complexes with beta(2)-glycoprotein I (beta(2)GPI). To test this hypothesis, chimeric fusion proteins were constructed of the dimerization domain (apple 4) of factor XI and beta(2)GPI. Both a

  20. Beta-limiting MHD instabilities in improved performance NSTX spherical torus plasmas

    International Nuclear Information System (INIS)

    Menard, J.E.; Bell, M.G.; Bell, R.E.

    2003-01-01

    Global magnetohydrodynamic stability limits in the National Spherical Torus Experiment (NSTX) have increased significantly recently due to a combination of device and operational improvements. First, more routine H-mode operation with broadened pressure profiles allows access to higher normalized beta and lower internal inductance. Second, the correction of a poloidal field coil induced error-field has largely eliminated locked tearing modes during nor- mal operation and increased the maximum achievable beta. As a result of these improvements, peak beta values have reached (not simultaneously) β t = 35%, β N 6.5, N > = 4.5, β / l i =10, and β= 1.4. High β P operation with reduced tearing activity has allowed a doubling of discharge pulse-length to just over 1 second with sustained periods of β N ∼ 6. Details of the β limit scalings and β-limiting instabilities in various operating regimes are described. (author)