Experimental Physical Sciences Vistas: MaRIE (draft)

Energy Technology Data Exchange (ETDEWEB)

Shlachter, Jack [Los Alamos National Laboratory

2010-09-08

To achieve breakthrough scientific discoveries in the 21st century, a convergence and integration of world-leading experimental facilities and capabilities with theory, modeling, and simulation is necessary. In this issue of Experimental Physical Sciences Vistas, I am excited to present our plans for Los Alamos National Laboratory's future flagship experimental facility, MaRIE (Matter-Radiation Interactions in Extremes). MaRIE is a facility that will provide transformational understanding of matter in extreme conditions required to reduce or resolve key weapons performance uncertainties, develop the materials needed for advanced energy systems, and transform our ability to create materials by design. Our unique role in materials science starting with the Manhattan Project has positioned us well to develop a contemporary materials strategy pushing the frontiers of controlled functionality - the design and tailoring of a material for the unique demands of a specific application. Controlled functionality requires improvement in understanding of the structure and properties of materials in order to synthesize and process materials with unique characteristics. In the nuclear weapons program today, improving data and models to increase confidence in the stockpile can take years from concept to new knowledge. Our goal with MaRIE is to accelerate this process by enhancing predictive capability - the ability to compute a priori the observables of an experiment or test and pertinent confidence intervals using verified and validated simulation tools. It is a science-based approach that includes the use of advanced experimental tools, theoretical models, and multi-physics codes, simultaneously dealing with multiple aspects of physical operation of a system that are needed to develop an increasingly mature predictive capability. This same approach is needed to accelerate improvements to other systems such as nuclear reactors. MaRIE will be valuable to many national

The risk of capsular breakage from phacoemulsification needle contact with the lens capsule: a laboratory study.

Science.gov (United States)

Meyer, Jay J; Kuo, Annie F; Olson, Randall J

2010-06-01

To determine capsular breakage risk from contact by phacoemulsification needles by machine and tip type. Experimental laboratory investigation. Infiniti (Alcon, Inc.) with Intrepid cartridges and Signature (Abbott Medical Optics, Inc.) phacoemulsification machines were tested using 19- and 20-gauge sharp and rounded tips. Actual and unoccluded flow vacuum were determined at 550 mm Hg, bottle height of 75 cm, and machine-indicated flow rate of 60 mL/minute. Breakage from brief tip contact with a capsular surrogate and human cadaveric lenses was calculated. Nineteen-gauge tips had more flow and less unoccluded flow vacuum than 20-gauge tips for both machines, with highest unoccluded flow vacuum in the Infiniti. The 19-gauge sharp tip was more likely than the 20-gauge sharp tip to cause surrogate breakage for Signature with micropulse and Ellips (Abbott Medical Optics, Inc.) ultrasound at 100% power. For Infiniti using OZil (Alcon, Inc.) ultrasound, 20-gauge sharp tips were more likely than 19-gauge sharp tips to break the membrane. For cadaveric lenses, using rounded 20-gauge tips at 100% power, breakage rates were micropulse (2.3%), Ellips (2.3%), OZil (5.3%). Breakage rates for sharp 20-gauge Ellips tips were higher than for rounded tips. Factors influencing capsular breakage may include active vacuum at the tip, flow rate, needle gauge, and sharpness. Nineteen-gauge sharp tips were more likely than 20-gauge tips to cause breakage in lower vacuum methods. For higher-vacuum methods, breakage is more likely with 20-gauge than with 19-gauge tips. Rounded-edge tips are less likely than sharp-edged tips to cause breakage. Copyright 2010 Elsevier Inc. All rights reserved.

Perspective: C60+ and laboratory spectroscopy related to diffuse interstellar bands

Science.gov (United States)

Campbell, E. K.; Maier, J. P.

2017-04-01

In the last 30 years, our research has focused on laboratory measurements of the electronic spectra of organic radicals and ions. Many of the species investigated were selected based on their potential astrophysical relevance, particularly in connection with the identification of appealing candidate molecules for the diffuse interstellar absorptions. Notably, carbon chains and derivatives containing hydrogen and nitrogen atoms in their neutral and ionic forms were studied. These data could be obtained after developing appropriate techniques to record spectra at low temperatures relevant to the interstellar medium. The measurement of gas phase laboratory spectra has enabled direct comparisons with astronomical data to be made and though many species were found to have electronic transitions in the visible where the majority of diffuse bands are observed, none of the absorptions matched the prominent interstellar features. In 2015, however, the first carrier molecule was identified: C60 + . This was achieved after the measurement of the electronic spectrum of C60 + -He at 6K in a radiofrequency ion trap.

Delayed diagnosis of homocystinuria presenting as bilateral congenital lens subluxation

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Jelić-Vuković Marija

2017-01-01

Full Text Available Introduction. Homocystinuria is an autosomal recessively inherited defect leading to hyperhomocysteinemia and associated with ocular manifestations, mainly myopia and ectopia lentis. Case outline. A 26-year-old male with secondary glaucoma due to bilateral lens subluxation was admitted to the Department of vitreoretinal surgery. Horizontal nystagmus, bilateral lens subluxation, and bilateral amblyopia were first discovered at the age of three years. Preoperative laboratory workup revealed elevated levels of homocysteine. Bilateral pars plana lensectomy and vitrectomy followed by a sulcus fixation of the intraocular lens (ALCON MA60 Acrysof IOL were performed. The patient was prescribed folic acid, methionine, and pyridoxine, and was urged to maintain a methionine-low diet. After a bilateral lensectomy and sulcus fixation of the intraocular lens and a methionine restriction therapy combined with vitamin B6, B9, and B12 supplementation, his condition improved greatly. Conclusion. In this report of a rare case we emphasize the importance of examining differential diagnoses of lens subluxation, since early intervention can prevent serious complications.

Accuracy of Alcon WaveLight® EX500 optical pachymetry during LASIK

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Mifflin MD

2017-08-01

Full Text Available Mark D Mifflin,1 Xavier M Mortensen,1 Brent S Betts,1 Cole Gross,2 Brian Zaugg1 1Department of Ophthalmology and Visual Sciences, John A Moran Eye Center, University of Utah, Salt Lake City, UT, 2University of Nevada School of Medicine, Reno, NV, USA Purpose: To study the accuracy and reliability of optical pachymetry using the Alcon WaveLight EX500 during laser-assisted in situ keratomileusis (LASIK. Materials and methods: This was a retrospective chart review of 90 eyes from 45 patients who had undergone LASIK (mean age 35.2±8.2 years; 19 males, 26 females. The WaveLight FS200 femtosecond laser was programmed to cut LASIK flaps at a desired depth of 120 µm. Optical low-coherence reflectometry (WaveLight EX500 was used to measure central corneal thickness prior to lifting the flap, and the residual stromal bed immediately after excimer ablation. Flap thickness (FT was calculated using simple subtraction. Optical coherence tomography (OCT was used to measure central corneal thickness, flap thickness, and residual stromal bed in the postoperative period and the results compared to intraoperative measurements. Results: Mean programmed FS200 FT was 119 µm. Mean FT using EX500 optical pachymetry was 109 µm. The difference between FS200- programmed and EX500-measured FT was 9 µm (P<0.001. There was also a significant difference between the EX500 and OCT FT (109 µm vs 119 µm, respectively; P<0.001. Conclusion: FT values calculated using intraoperative EX500 optical pachymetry were significantly lower than programmed FS200 values or OCT measurements. Keywords: flap thickness, optical coherence tomography, femtosecond laser

Contact Aligner 2 (Front Side): Suss Microtec MA8

Data.gov (United States)

Federal Laboratory Consortium — Description:CORAL Name: SussMA8This system utilizes 1X contact lithography to transfer photomask patterns onto substrates Specifications / Capabilities:UV broadband...

21 CFR 212.60 - What requirements apply to the laboratories where I test components, in-process materials, and...

Science.gov (United States)

2010-04-01

... maintenance. Each laboratory must have and follow written procedures to ensure that equipment is routinely... 21 Food and Drugs 4 2010-04-01 2010-04-01 false What requirements apply to the laboratories where...) Laboratory Controls § 212.60 What requirements apply to the laboratories where I test components, in-process...

Field and laboratory evaluation of the mobility of cobalt-60/EDTA in an arid environment

International Nuclear Information System (INIS)

Jones, T.L.; Gee, G.W.; Swanson, J.L.; Kirkham, R.R.

1983-02-01

The ability of the organic complexant EDTA to enhance the mobility of cobalt-60 was investigated in both laboratory and field experiments. Laboratory tests consisted of short term (approximately 7 day) column and batch adsorption tests using soil from the Hanford site as well as long term (approximately 70 day) batch tests with Hanford soil and soils from Oak Ridge and Savannah River. In addition, two large scale tracer tests were conducted using Hanford soil. One used a large (1.6 m) laboratory column, spiked with cobalt-60/EDTA and the other was a field test conducted in an 8 m deep lysimeter. Enhanced mobility decreased sorption were observed in both column and batch tests when the cobalt-60/EDTA solutions contacted Hanford and Oak Ridge soil for only a few days. When long contact times were allowed (months) the Hanford soil showed large increases in sorption with time. The low sorption exhibited initially by the Oak Ridge soil increased slightly over time, however, the high sorption observed with the Savannah River soil remained constant with time. The reduced mobility, with time, observed in Hanford soils was confirmed in both the large scale laboratory and breaking down when contacted with Hanford and Savannah River soil and to a lesser extent, the Oak Ridge soil. It is not known at this time why the complex is breaking down or why the kinetics are different among the soils tested. The implication to waste management is that the potential for transport of cobalt by EDTA complexation may not be as serious as once thought

Anti-Ma2 antibody related paraneoplastic limbic/brain stem encephalitis associated with breast cancer expressing Ma1, Ma2, and Ma3 mRNAs.

Science.gov (United States)

Sahashi, K; Sakai, K; Mano, K; Hirose, G

2003-09-01

A 69 year old woman presented with cognitive impairment and supranuclear gaze palsy caused by paraneoplastic limbic/brain stem encephalitis associated with atypical medullary breast carcinoma. The cerebrospinal fluid from the patient harboured an anti-neuronal cell antibody against Ma2 antigen, but not against Ma1 or Ma3 antigen. Despite the antibody being restricted to the Ma2 antigen, the patient's cancer tissue expressed Ma1, Ma2, and Ma3 mRNAs. These results, and the expression of Ma2 mRNA in an atypical medullar breast carcinoma in another patient without paraneoplastic encephalitis, indicate that the induction of anti-Ma2 antibody depends on host immunoreponsiveness and not on the presence of the antigen itself in the cancer.

Development of H- sources at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Prelec, K.

1977-01-01

Negative hydrogen ion sources have been developed at Brookhaven National Laboratory for several years, with the initial goal to design a source for accelerator applications and later on to design a large unit for applications in neutral beam injectors of magnetic fusion devices. Three types of sources were investigated, a hollow discharge duoplasmatron yielding H - currents up to 60 mA, a Penning source yielding H - currents up to 440 mA, and a magnetron source yielding H - currents up to 1 A. All sources operate with a mixture of hydrogen gas and cesium vapors, and H - ions are most likely produced on cesium covered electrode surfaces. A larger model of a Penning/magnetron source was constructed and will be tested soon; it incorporates among other new features a system for the cooling of the cathode

Contact Aligner 1 (Front and Back Side): Suss Microtec MA6

Data.gov (United States)

Federal Laboratory Consortium — Description:CORAL Name: SussMA6This system utilizes 1X contact lithography to transfer photomask patterns onto substrates Specifications / Capabilities:UV broadmand...

Spatially and financially explicit population viability analysis of Maculinea alcon in The Netherlands.

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Viktoriia Radchuk

Full Text Available The conservation of species structured in metapopulations involves an important dilemma of resource allocation: should investments be directed at restoring/enlarging habitat patches or increasing connectivity. This is still an open question for Maculinea species despite they are among the best studied and emblematic butterfly species, because none of the population dynamics models developed so far included dispersal.We developed the first spatially and financially explicit Population Viability Analysis model for Maculinea alcon, using field data from The Netherlands. Implemented using the RAMAS/GIS platform, the model incorporated both local (contest density dependence, environmental and demographic stochasticities, and regional population dynamics (dispersal rates between habitat patches. We selected four habitat patch networks, contrasting in several basic features (number of habitat patches, their quality, connectivity, and occupancy rate to test how these features are affecting the ability to enhance population viability of four basic management options, designed to incur the same costs: habitat enlargement, habitat quality improvement, creation of new stepping stone habitat patches, and reintroduction of captive-reared butterflies. The PVA model was validated by the close match between its predictions and independent field observations on the patch occupancy pattern. The four patch networks differed in their sensitivity to model parameters, as well as in the ranking of management options. Overall, the best cost-effective option was enlargement of existing habitat patches, followed by either habitat quality improvement or creation of stepping stones depending on the network features. Reintroduction was predicted to generally be inefficient, except in one specific patch network.Our results underline the importance of spatial and regional aspects (dispersal and connectivity in determining the impact of conservation actions, even for a species

[60]Fullerene Displacement from (Dihapto-Buckminster-Fullerene) Pentacarbonyl Tungsten(0): An Experiment for the Inorganic Chemistry Laboratory, Part II

Science.gov (United States)

Cortes-Figueroa, Jose E.; Moore-Russo, Deborah A.

2006-01-01

The kinetics experiments on the ligand-C[subscript 60] exchange reactions on (dihapto-[60]fullerene) pentacarbonyl tungsten(0), ([eta][superscript 2]-C[subscript 60])W(CO)[subscript 5], form an educational activity for the inorganic chemistry laboratory that promotes graphical thinking as well as the understanding of kinetics, mechanisms, and the…

33 CFR 80.135 - Hull, MA to Race Point, MA.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Hull, MA to Race Point, MA. 80... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.135 Hull, MA to Race Point, MA. (a... the east coast of Massachusetts from the easternmost radio tower at Hull, charted in approximate...

42 CFR 495.202 - Identification of qualifying MA organizations, MA-EPs and MA-affiliated eligible hospitals.

Science.gov (United States)

2010-10-01

... qualifying MA-affiliated eligible hospitals under the MA EHR incentive program are required to identify...-EPs and MA-affiliated eligible hospitals. 495.202 Section 495.202 Public Health CENTERS FOR MEDICARE... STANDARDS FOR THE ELECTRONIC HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to Medicare...

A laboratory and field evaluation of the mobility of cobalt-60/EDTA

International Nuclear Information System (INIS)

Jones, T.L.; Gee, G.W.; Kirkham, R.R.; Swanson, J.L.

1983-01-01

We have observed a time and soil type dependence in the ability of the organic complexant EDTA to keep cobalt-60 in solution. Test results indicate that short-term adsorption tests lasting 5 days or less can be misleading. In short-term tests using cobalt-60/EDTA and soil from the Hanford site, low sorption in batch tests and high mobility in column tests were observed. During long-term batch test using cobalt-60/EDTA, the percentage of cobalt remaining in solution decreased from 90% after 7 days to less than 10% after 500 days. In laboratory and field column tests where low water flow rates allowed long contact time, virtually no cobalt movement was observed even though in the field test tritium was transported over 4 meters. Long-term batch tests using cobalt-60/EDTA and soil from Savannah River burial grounds showed that cobalt remainin in solution dropped to 30% of the total cobalt added after 5 days and to less than 1% after 15 days. Batch tests using soil from Oak Ridge burial grounds were less dramatic showing cobalt in solution decreasing from 90% after 5 days to 70% after 35 days. The cobalt-60/EDTA complex appears to be dissociating and leaving uncomplexed cobalt which is readily sorbed. The dissociation seems to be rather complete in Hanford and Savannah River soil but limited in the Oak Ridge soil. The implication to waste management is that the potential for transport of cobalt by EDTA may not be as serious at all burial sites as once thought

Ma

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Ingrid Berthon-Moine

2012-01-01

Full Text Available Ma (2009 is a single channel video of a mother and child walking together side by side, holding hands. The title is reminiscent of the affectionate nickname for a mother, 'Ma', but also a concealed way to convey maternal ambivalence. Maternal ambivalence is the result of the tension between the idealisation of motherhood and women’s lived experience of mothering. The maternal struggle finds its source in the difficulty of identifying with the ideological representation of the mother. This image still conveys an idealistic and nostalgic, patriarchal image of maternal love bounded by culture and history. http://podcast.ulcc.ac.uk/accounts/BirkbeckCollege/mamsie/MA.mov

The Mesoscale Science of the Matter-Radiation Interactions in Extremes (MaRIE) project

Energy Technology Data Exchange (ETDEWEB)

Kippen, Karen Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Montoya, Donald Raymond [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-08-17

The National Nuclear Security Administration (NNSA) requires the ability to understand and test how material structures, defects, and interfaces determine performance in extreme environments such as in nuclear weapons. To do this, MaRIE will be an x-ray source that is laser-like and brilliant with very fl exible and fast pulses to see at weapons-relevant time scales, and with high enough energy to study critical materials. The Department of Energy (DOE) has determined there is a mission need for MaRIE to deliver this capability. MaRIE can use some of the existing infrastructure of the Los Alamos Neutron Science Center (LANSCE) and its accelerator capability. MaRIE will be built as a strategic partnership of DOE national laboratories and university collaborators.

Phacoemulsification tip vacuum pressure: Comparison of 4 devices.

Science.gov (United States)

Payne, Marielle; Georgescu, Dan; Waite, Aaron N; Olson, Randall J

2006-08-01

To determine the vacuum pressure generated by 4 phacoemulsification devices measured at the phacoemulsification tip. University ophthalmology department. The effective vacuum pressures generated by the Sovereign (AMO), Millennium (Bausch & Lomb), Legacy AdvanTec (Alcon Laboratories), and Infiniti (Alcon Laboratories) phacoemulsification machines were measured with a device that isolated the phacoemulsification tip in a chamber connected to a pressure gauge. The 4 machines were tested at multiple vacuum limit settings, and the values were recorded after the foot pedal was fully depressed and the pressure had stabilized. The AdvanTec and Infiniti machines were tested with and without occlusion of the Aspiration Bypass System (ABS) side port (Alcon Laboratories). The Millennium machine was tested using venturi and peristaltic pumps. The machines generated pressures close to the expected at maximum vacuum settings between 100 mm Hg and 500 mm Hg with few intermachine variations. There was no significant difference between pressures generated using 19- or 20-gauge tips (Millennium and Sovereign). The addition of an ABS side port decreased vacuum by a mean of 12.1% (P < .0001). Although there were some variations in vacuum pressures among phacoemulsification machines, particularly when an aspiration bypass tip was used, these discrepancies are probably not clinically significant.

Effect of Cistanche deserticola Ma extract on memory of aged mice

African Journals Online (AJOL)

Age-related learning and memory disorders have ... Plant material and extraction ... The plant extract (CDME) was obtained by steeping the dried Cistanche deserticola Ma in 60 °C water for. 1 h. ... glass bottle, labeled, and stored in a deep.

The structural analysis of zinc borate glass by laboratory EXAFS and X-ray diffraction measurements

International Nuclear Information System (INIS)

Kajinami, Akihiko; Harada, Yasushi; Inoue, Shinsuke; Deki, Shigehito; Umesaki, Norimasa

1999-01-01

The structure of zinc borate glass has been investigated by laboratory EXAFS and X-ray diffraction measurement as preliminary investigations for the detailed study in SPring-8. The zinc borate glass was prepared in the range from 40 to 65 mol% of zinc oxide content. The X-ray diffraction was measured by horizontal θ-θ goniometer with 60 kV and 300 mA output of Mo target. The EXAFS of zinc borate glass was measured by laboratory EXAFS system with 20 kV, 100 mA output of Mo target for the K absorption edge of zinc atom. From the X-ray diffraction and the EXAFS measurements, it is found that the zinc ion is surrounded by four oxygen atoms and formed a tetrahedral structure whose (Zn-O) distance is about 2 A and that the structure is unchanged with the zinc oxide content. The diffraction data show that the neighboring structure of boron atom transforms from BO 4 tetrahedra to BO 3 tetragonal planar structure with increasing of the zinc oxide content. (author)

Breast compression and radiation dose in two different mammographic oblique projections: 45 and 60 deg

International Nuclear Information System (INIS)

Brnic, Zoran; Hebrang, Andrija

2001-01-01

Introduction: Standard mammography includes two views, craniocaudal and medio-lateral oblique. Depending on patient's body constitution, central beam angle in mediolateral oblique projection may vary, with 45 deg. being suitable for the majority of patients in routine daily practice. With continuous improvement in X-ray technology and radiographers' training, the risk of radiation induced cancerogenesis is considerably reduced and acceptable when compared to benefit. However, the risk still exists, being cumulative and directly related to absorbed glandular dose. There is no minimal dose of radiation which is absolutely harmless, and every effort to reduce the dose is welcome. In this retrospective study two different angles (45 vs. 60 deg.) of mediolateral oblique view were compared according to radiation dose and efficacy of breast compression. Patients and methods: In 52 women, additional 60 deg. oblique films were done after craniocaudal and mediolateral oblique 45 deg.-films, with the same kVp and positioning technique. Breast thickness, time-current products (mA s) and absorbed doses were compared between 45 deg. - and 60 deg.-films. Subgroups of women with large, small, prominent and pendulous breasts were analyzed separately, following the same methodology as for the whole group. Results: mA s were 11.5% lower and compression 7% better with an angle of 60 deg. than with 45 deg. In the subgroup of women with small breasts, mA s values were 13% lower and compression 9% better with 60 deg. than with 45 deg., while in the subgroup with large breasts, mA s were 9% lower and compression 5% better. In the subgroup of patients with pendulous breasts, mA s values were 12% lower and compression 10% better with 60 deg. than with 45 deg., while in the subgroup with prominent breasts, mA s values were 4% lower and compression 3% better. Absorbed glandular dose was estimated to be approximately 20% lower when an oblique mammogram was done with 60 deg. instead of 45 deg

Images documentaires dans le récit décolonisateur. Le cinéma politique latino-américain des années 60 et 70

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Susana Sel

2009-05-01

Full Text Available Cet article évalue l’apport au genre documentaire du Nouveau Cinéma Latino-américain des années soixante et soixante-dix. Dépassant l’opposition fiction-réalité, le Nouveau Cinéma Latino-américain promeut un cinéma de critique sociale grâce à des récits dont les formes varient, mais qui tous contestent la réalité de la domination impérialiste et plaident pour une réhabilitation des cultures et des identités réprimées. Ces nouveaux créateurs, engagés dans la lutte de libération de leurs peuples, sont à l’origine d’ « œuvres ouvertes », destinées à être poursuivies et achevées par l’action des nouveaux spectateurs latino-américains.El artículo aborda la incidencia del documental en el Nuevo Cine Latinoamericano de las décadas del ’60 y principios de los ’70. Superando la dicotomía ficción-realidad, y en una gran diversidad de discursos, el Nuevo Cine Latinoamericano impulsó un cine crítico, de sentido social, en relatos que niegan la realidad de la dominación imperialista y proponen recuperar culturas e identidades colectivas avasalladas. Estos nuevos enunciadores comprometidos con las luchas de liberación de sus pueblos, crearon “obras abiertas” que se completarían y articularían con la acción de nuevos espectadores latinoamericanos.

Physical design of JT-60 Super Upgrade

International Nuclear Information System (INIS)

Nagashima, K.; Kikuchi, M.; Kurita, G.; Ozeki, T.; Aoyagi, T.; Ushigusa, K.; Neyatani, Y.; Kubo, T.; Mori, K.; Nakagawa, S.; Kuriyama, M.; Nagami, M.

1997-01-01

The JT-60 Super Upgrade (JT-60SU) is an upgraded tokamak device of JT-60U for developing the steady-state reactor and advanced tokamak operation in the International Thermonuclear Experimental Reactor. The device is planned to utilize the JT-60 facilities fully and to minimize the needed modification. The major radius is 4.8 m and the maximum plasma current is 10 MA. Neutral beam injection with 750 keV beam energy is the primary heating method. The machine is capable of steady-state operation with high density up to 8.8 x 10 19 m -3 at 5 MA plasma current. The high operating density, over the Greenwald et al. limit, is critically important in order to achieve high bootstrap current fraction. Ballooning mode and low n ideal magnetohydrodynamic (MHD) mode including the bootstrap current were analyzed for steady-state operation. The current profile must be optimized to obtain a normalized beta up to 3. The plasma configuration with high triangularity was adopted in order to get good MHD stability and high energy confinement. A compact divertor was designed in order to get the large plasma space. (orig.)

Zhigang Ma

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. Zhigang Ma. Articles written in Bulletin of Materials Science. Volume 35 Issue 4 August 2012 pp 575-578. Degradation and miscibility of poly(DL-lactic acid)/poly(glycolic acid) composite films: Effect of poly(DL-lactic-co-glycolic acid) · Zhigang Ma Na Zhao Chengdong Xiong.

CoMA, an experiment for the detailed in-situ analysis of collected cometary particulates

International Nuclear Information System (INIS)

Kissel, J.; Fechtig, H.; Jessberger, E.K.; Krueger, F.R.; Niemczyk, N.; Schaefer, G.; Zscheeg, H.

1989-01-01

After NASA accepted for the implementation phase (up to October 1990) our proposal for the CoMA investigation to be flown onboard CRAF to rendezvous with a comet, funding by the BMFT for instrument pre-development has been obtained. Most contracts could be let, some, however, with substantial delay due to administrative problems. Progress can be reported as the group in Bremen could demonstrate a mass resolution of 60 000 for a low magnetic field ICR-experiment, resolving 12 CH + and 13 C + ions. Also a first successful attempt was made to theoretically describe the dust collection efficiencies of different materials. As yet such a model did not exist - a fact that made the interpretation and extrapolation of laboratory data obsolete. The experimental setup in which the Indium liquid ion source is tested could be completed by the successful addition of a bunching structure. In future it will serve those partners that develop in detail the primary beam system. (orig.)

PF magnetic design for the 4MA reversed field pinch experiment CPRF

International Nuclear Information System (INIS)

Gribble, R.F.; Rogers, J.D.

1987-01-01

ZTH is to reach 2 MA by inductive energy transfer in 0.05 s followed by power supply ramping to 4 MA in 0.4 s. Major and minor radii are 2.4 and 0.4 m. Copper for the poloidal field coils weighs 48 metric tonnes, the one-turn equivalent ohmic heating (OH) coil inductance is 1.90 μH, and the OH coil rating is 15.4 MAT, 225 MJ, and 29.3 Vs at 60 kA. The normal operating OH current is 50 kA. Design of the coil for 60 kA provides a margin for uncertainties. OH coils are connected in series and the combination is connected in parallel with four equilibrium field (EF) coils. With optimized location of all coils, this connection provides decoupling between the OH and EH coil sets so that the changing OH current does not affect EF winding current. 3 refs., 2 figs., 1 tab

Scaling of X pinches from 1 MA to 6 MA

International Nuclear Information System (INIS)

Bland, Simon Nicholas; McBride, Ryan D.; Wenger, David Franklin; Sinars, Daniel Brian; Chittenden, Jeremy Paul; Pikuz, Sergei A.; Harding, Eric; Jennings, Christopher A.; Ampleford, David J.; Yu, Edmund P.; Cuneo, Michael Edward; Shelkovenko, Tatiana A.; Hansen, Stephanie B.

2010-01-01

This final report for Project 117863 summarizes progress made toward understanding how X-pinch load designs scale to high currents. The X-pinch load geometry was conceived in 1982 as a method to study the formation and properties of bright x-ray spots in z-pinch plasmas. X-pinch plasmas driven by 0.2 MA currents were found to have source sizes of 1 micron, temperatures >1 keV, lifetimes of 10-100 ps, and densities >0.1 times solid density. These conditions are believed to result from the direct magnetic compression of matter. Physical models that capture the behavior of 0.2 MA X pinches predict more extreme parameters at currents >1 MA. This project developed load designs for up to 6 MA on the SATURN facility and attempted to measure the resulting plasma parameters. Source sizes of 5-8 microns were observed in some cases along with evidence for high temperatures (several keV) and short time durations (<500 ps).

New developments and applications of intense pulsed radiation sources at Sandia National Laboratories

Energy Technology Data Exchange (ETDEWEB)

Cook, D.

1998-02-01

In the past thirty-six months, tremendous strides have been made in x-ray production using high-current z-pinches. Today, the x-ray energy (1.9 MJ) and power (200 TW) output of the Z accelerator (formerly PBFA-II) is the largest available in the laboratory. These z-pinch x-ray sources are being developed for research into the physics of high energy density plasmas of interest in weapon behavior and in inertial confinement fusion. Beyond the Z accelerator current of 20 MA, an extrapolation to the X-1 accelerator level of 60 MA may have the potential to drive high-yield ICF reactions at affordable cost if several challenging technical problems can be overcome. New developments have also taken place at Sandia in the area of high current, mm-diameter electron beams for advanced hydrodynamic radiography. On SABRE, x-ray spot diameters were less than 2 mm with a dose of 100 R at 1 meter in a 40 ns pulse.

Effect of harvest time on fermentation profiles of maize ensiled in laboratory silos and determination of drying losses at 60°C

DEFF Research Database (Denmark)

Nielsen, Tina Skau; Kristensen, Niels Bastian; Weisbjerg, Martin Riis

2007-01-01

The objectives were to investigate the effect of premature ensiling of maize on alcohol fermentation in laboratory silos and the loss of fermentation products and glucose in silage following drying at 60°C for 48 h. During four consecutive weeks maize was harvested and ensiled for 60 days in vacuum-sealed...

Discovery and utilization of sorghum genes (Ma5/Ma6)

Science.gov (United States)

Mullet, John E; Rooney, William L; Klein, Patricia E; Morishige, Daryl; Murphy, Rebecca; Brady, Jeff A

2012-11-13

Methods and composition for the production of non-flowering or late flowering sorghum hybrid. For example, in certain aspects methods for use of molecular markers that constitute the Ma5/Ma6 pathway to modulate photoperiod sensitivity are described. The invention allows the production of plants having improved productivity and biomass generation.

Clinical analysis of anti-Ma2-associated encephalitis.

Science.gov (United States)

Dalmau, Josep; Graus, Francesc; Villarejo, Alberto; Posner, Jerome B; Blumenthal, Deborah; Thiessen, Brian; Saiz, Albert; Meneses, Patricio; Rosenfeld, Myrna R

2004-08-01

Increasing experience indicates that anti-Ma2-associated encephalitis differs from classical paraneoplastic limbic or brainstem encephalitis, and therefore may be unrecognized. To facilitate its diagnosis we report a comprehensive clinical analysis of 38 patients with anti-Ma2 encephalitis. Thirty-four (89%) patients presented with isolated or combined limbic, diencephalic or brainstem dysfunction, and four with other syndromes. Considering the clinical and MRI follow-up, 95% of the patients developed limbic, diencephalic or brainstem encephalopathy. Only 26% had classical limbic encephalitis. Excessive daytime sleepiness affected 32% of the patients, sometimes with narcolepsy-cataplexy and low CSF hypocretin. Additional hormonal or MRI abnormalities indicated diencephalic-hypothalamic involvement in 34% of the patients. Eye movement abnormalities were prominent in 92% of the patients with brainstem dysfunction, but those with additional limbic or diencephalic deficits were most affected; 60% of these patients had vertical gaze paresis that sometimes evolved to total external ophthalmoplegia. Three patients developed atypical parkinsonism, and two a severe hypokinetic syndrome with a tendency to eye closure and dramatic reduction of verbal output. Neurological symptoms preceded the tumour diagnosis in 62% of the patients. Brain MRI abnormalities were present in 74% of all patients and 89% of those with limbic or diencephalic dysfunction. Among the 34 patients with cancer, 53% had testicular germ-cell tumours. Two patients without evidence of cancer had testicular microcalcification and one cryptorchidism, risk factors for testicular germ-cell tumours. After neurological syndrome development, 17 of 33 patients received oncological treatment (nine also immunotherapy), 10 immunotherapy alone, and six no treatment. Overall, 33% of the patients had neurological improvement, three with complete recovery; 21% had long-term stabilization, and 46% deteriorated. Features

Review of JT-60U experimental results from March to October, 1991

International Nuclear Information System (INIS)

1992-06-01

Experimental results achieved in the initial operation of JT-60U are described in this paper. Experiments of JT-60U were initiated in March 1991, and deuterium experiments started in the middle of July. Multivariable non-interacting control, H-mode experiments, the high-q and high-β p regime with hot ion enhanced confinement, the divertor heat flux, etc. are reported. Achieved values of the first experiment of the JT-60U LHCD in 1991 were P LH = 1.5 MW, driven current I RF = 2MA, current drive efficiency η CD (=n-bar e R p I RF /P LH ) = 0.25 x 10 20 m -2 A/W and current driven product CDP(=n-bar e R p I RF ) = 3 x 10 20 m -2 MA. (J.P.N.)

MoMaS reactive transport benchmark using PFLOTRAN

Science.gov (United States)

Park, H.

2017-12-01

MoMaS benchmark was developed to enhance numerical simulation capability for reactive transport modeling in porous media. The benchmark was published in late September of 2009; it is not taken from a real chemical system, but realistic and numerically challenging tests. PFLOTRAN is a state-of-art massively parallel subsurface flow and reactive transport code that is being used in multiple nuclear waste repository projects at Sandia National Laboratories including Waste Isolation Pilot Plant and Used Fuel Disposition. MoMaS benchmark has three independent tests with easy, medium, and hard chemical complexity. This paper demonstrates how PFLOTRAN is applied to this benchmark exercise and shows results of the easy benchmark test case which includes mixing of aqueous components and surface complexation. Surface complexations consist of monodentate and bidentate reactions which introduces difficulty in defining selectivity coefficient if the reaction applies to a bulk reference volume. The selectivity coefficient becomes porosity dependent for bidentate reaction in heterogeneous porous media. The benchmark is solved by PFLOTRAN with minimal modification to address the issue and unit conversions were made properly to suit PFLOTRAN.

Morotochoerus from Uganda (17.5 Ma and Kenyapotamus from Kenya (13-11 Ma: implications for hippopotamid origins

Directory of Open Access Journals (Sweden)

Pickford, M.

2011-12-01

Full Text Available The aim of this paper is to describe and interpret suiform teeth from Moroto, Uganda, and Ngorora, Kenya, which contribute to the debate about hippo-anthracothere-whale relationships. The early stages of hippopotamid evolution are relatively poorly known on account of the paucity of their fossil record older than 7 Ma. New specimens of Morotochoerus from Uganda reveal that it is not closely related to Hippopotamidae; the superficial resemblances of the cheek teeth to those of hippos represent convergences and not homologies. Restricted samples of Palaeopotamus ternani are available from the Middle Miocene of Kenya {Maboko, ca 16 Ma; Muruyur, ca 14.5 Ma; Fort Ternan, ca 13.7 Ma} while from the base of the late Miocene, Kenyapotamus coryndonae is known from Kenya {Ngerngerwa, ca 10.5-10 Ma; Nakali, ca 10.5 Ma; Samburu Hills, ca 9.5 Ma}, Ethiopia {Ch’orora, ca 10.5 Ma} and Tunisia {Beglia Formation ca 11-10 Ma}. The recovery of specimens of Kenyapotamus from the Ngorora Formation, Kenya, aged ca 11 Ma, is of interest because it includes well preserved teeth, including an m/3 in good condition. These specimens support the hypothesis that hippopotamids descended from palaeochoerids and not from anthracotheres.El objetivo de este trabajo es describir e interpretar los dientes suiformes de Moroto, Uganda, y Ngorora, Kenia, que contribuyen al debate sobre las relaciones hipo-anthracothere-whale. Las primeras etapas de la evolución de los hipopotámidos son relativamente poco conocidas a causa de la escasez de su registro fósil en edades superiors a los 7 Ma. Nuevos ejemplares de Morotochoerus en Uganda revelan que no están estrechamente relacionados con Hippopotamidae, las semejanzas superficiales de los dientes de la mandíbula con los de los hipopótamos representan convergencias y no homologías. Algunas muestras de Palaeopotamus ternani aparecen en el Medio Mioceno de Kenia {Maboko, ca 16 Ma; Muruyur, ca 14.5 Ma; Fort Ternan, ca 13.7 Ma

Minor Actinide Laboratory at JRC-ITU: Fuel fabrication facility

International Nuclear Information System (INIS)

Fernandez, A.; McGinley, J.; Somers, J.

2008-01-01

The Minor Actinide Laboratory (MA-lab) of the Institute for Transuranium Elements is a unique facility for the fabrication of fuels and targets containing minor actinides (MA). It is of key importance for research on Partitioning and Transmutation in Europe, as it is one of the only dedicated facilities for the fabrication of MA containing materials, either for property measurements or for the production of test pins for irradiation experiments. In this paper a detailed description of the MA-Lab facility and the fabrication processes developed to fabricate fuels and samples containing high content of minor actinides is given. In addition, experience gained and improvements are also outlined. (authors)

Review of JT-60 experiment (March 1986)

International Nuclear Information System (INIS)

1986-11-01

Results of JT-60 experiment with ohmic heating in March 1986 are summarized. A maximum plasma current of 2 MA, an average plasma density of 5.7 x 10 19 m -3 and energy confinement time of 0.4 - 0.5 sec were obtained. Detailed characteristics of ohmic plasmas are discussed. (author)

Model for Analysis of the Energy Demand (MAED) users' manual for version MAED-1

International Nuclear Information System (INIS)

1986-09-01

This manual is organized in two major parts. The first part includes eight main sections describing how to use the MAED-1 computer program and the second one consists of five appendices giving some additional information about the program. Concerning the main sections of the manual, Section 1 gives a summary description and some background information about the MAED-1 model. Section 2 extends the description of the MAED-1 model in more detail. Section 3 introduces some concepts, mainly related to the computer requirements imposed by the program, that are used throughout this document. Sections 4 to 7 describe how to execute each of the various programs (or modules) of the MAED-1 package. The description for each module shows the user how to prepare the control and data cards needed to execute the module and how to interpret the printed output produced. Section 8 recapitulates about the use of MAED-1 for carrying out energy and electricity planning studies, describes the several phases normally involved in this type of study and provides the user with practical hints about the most important aspects that need to be verified at each phase while executing the various MAED modules

Mapping Nearby Galaxies at APO: The MaNGA IFU Galaxy Survey

Science.gov (United States)

Law, David R.; MaNGA Team

2014-01-01

MaNGA is a new survey that will begin in August 2014 as part of SDSS-IV with the aim of obtaining integral-field spectroscopy for an unprecedented sample of 10,000 nearby galaxies. MaNGA's key goals are to understand the "life cycle" of present day galaxies from imprinted clues of their birth and assembly, through their ongoing growth via star formation and merging, to their death from quenching at late times. To achieve these goals, MaNGA will channel the impressive capabilities of the SDSS-III BOSS spectrographs in a fundamentally new direction by marshaling the unique power of 2D spectroscopy. MaNGA will deploy 17 pluggable Integral Field Units (IFUs) made by grouping fibers into hexagonal bundles ranging from 19 to 127 fibers each. The spectra obtained by MaNGA will cover the wavelength range 3600-10,000 Angstroms (with a velocity resolution of ~ 60 km/s) and will characterize the internal composition and the dynamical state of a sample of 10,000 galaxies with stellar masses greater than 10^9 Msun and an average redshift of z ~ 0.03. Such IFU observations enable a leap forward because they provide an added dimension to the information available for each galaxy. MaNGA will provide two-dimensional maps of stellar velocity and velocity dispersion, mean stellar age and star formation history, stellar metallicity, element abundance ratio, stellar mass surface density, ionized gas velocity, ionized gas metallicity, star formation rate, and dust extinction for a statistically powerful sample. This legacy dataset will address urgent questions in our understanding of galaxy formation, including 1) The formation history of galaxy subcomponents, including the disk, bulge, and dark matter halo, 2) The nature of present-day galaxy growth via merging and gas accretion, and 3) The processes responsible for terminating star formation in galaxies. Finally, MaNGA will also play a vital role in the coming era of advanced IFU instrumentation, serving as the low-z anchor for

Stormwater Pollution Prevention Plan for the TA-60-01 Heavy Equipment Shop, Los Alamos National Laboratory, Revision 3, January 2018

Energy Technology Data Exchange (ETDEWEB)

Burgin, Jillian Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2018-02-01

This Storm Water Pollution Prevention Plan (SWPPP) was developed in accordance with the provisions of the Clean Water Act (33 U.S.C. §§1251 et seq., as amended), and the Multi-Sector General Permit for Storm Water Discharges Associated with Industrial Activity (U.S. EPA, June 2015) issued by the U.S. Environmental Protection Agency (EPA) for the National Pollutant Discharge Elimination System (NPDES) and using the industry specific permit requirements for Sector P-Land Transportation and Warehousing as a guide. This SWPPP applies to discharges of stormwater from the operational areas of the TA-60-01 Heavy Equipment Shop at Los Alamos National Laboratory. Los Alamos National Laboratory (also referred to as LANL or the “Laboratory”) is owned by the Department of Energy (DOE), and is operated by Los Alamos National Security, LLC (LANS). Throughout this document, the term “facility” refers to the TA-60-01 Heavy Equipment Shop and associated areas. The current permit expires at midnight on June 4, 2020.

Pfister y la Hibridación del Maíz

Directory of Open Access Journals (Sweden)

Kent. George

1940-03-01

Full Text Available En la Facultad Nacional de Agronomía, se están haciendo actualmente los trabajos de aclimatación del "maíz hibrido Pfister". Cuando el suscrito tuvo conocimiento del "maíz híbrido" obtenido como fruto de una experimentación de más de 20 años llevada a cabo en Illinois por el señor Pfister, se interesó vivamente en traer unas semillas a Colombia para intentar el proceso de aclimatación de las mejores variedades. A pesar de una larga correspondencia con el señor Pfister desde hace dos años, no nos fue posible lograr nuestro objeto. Durante la última visita del suscrito a ese país, obtuve, como una merced personal, una muy pequeña cantidad de las ocho mejores variedades de maíz híbrido, y al efecto, a la presente le estoy incluyendo a usted esas semillas de maíz sin otra retribución para nosotros, que el de hacer las siembras, observaciones y experimentaciones con todo el cuidado de que usted es capaz, y darnos cuenta oportuna de los resultados obtenidos con cada una de las variedades. Cada talego está marcado con el número de la variedad y no está por demás rogar a usted de la manera más encarecida llevar a efecto este trabajo con el mayor cuidado e interés para corresponder por lo menos al que hemos tenido nosotros en proporcionarle las dichas semillas. A pesar de que en Estados Unidos han hecho una súper selección de maíz en los últimos 50 años, las semillas seleccionadas han; quedado superadas por el maíz "Híbrido Pfister" con rendimientos de más de un 60%. Como nosotros no hemos hecho nada en selección de maíz, nuestro trabajo se puede limitar a un proceso de "aclimatación", que si logramos, tendríamos ganados muchos años de trabajo.

Phase B - final definition and preliminary design study for the initial Atmospheric Cloud Physics Laboratory (ACPL): A spacelab mission payload. Work breakdown structure for phase C/D DR-MA-06 (preliminary issue)

Science.gov (United States)

1976-01-01

The Work Breakdown Structure (WBS) and Dictionary (DR-MA-06) for initial and subsequent flights of the Atmospheric Cloud Physics Laboratory (ACPL) is presented. An attempt is made to identify specific equipment and components in each of the eleven subsystems; they are listed under the appropriate subdivisions of the WBS. The reader is cautioned that some of these components are likely to change substantially during the course of the study, and the list provided should only be considered representative.

High current, 0.5-MA, fast, 100-ns, linear transformer driver experiments

Directory of Open Access Journals (Sweden)

Michael G. Mazarakis

2009-05-01

Full Text Available The linear transformer driver (LTD is a new method for constructing high current, high-voltage pulsed accelerators. The salient feature of the approach is switching and inductively adding the pulses at low voltage straight out of the capacitors through low inductance transfer and soft iron core isolation. Sandia National Laboratories are actively pursuing the development of a new class of accelerator based on the LTD technology. Presently, the high current LTD experimental research is concentrated on two aspects: first, to study the repetition rate capabilities, reliability, reproducibility of the output pulses, switch prefires, jitter, electrical power and energy efficiency, and lifetime measurements of the cavity active components; second, to study how a multicavity linear array performs in a voltage adder configuration relative to current transmission, energy and power addition, and wall plug to output pulse electrical efficiency. Here we report the repetition rate and lifetime studies performed in the Sandia High Current LTD Laboratory. We first utilized the prototype ∼0.4-MA, LTD I cavity which could be reliably operated up to ±90-kV capacitor charging. Later we obtained an improved 0.5-MA, LTD II version that can be operated at ±100  kV maximum charging voltage. The experimental results presented here were obtained with both cavities and pertain to evaluating the maximum achievable repetition rate and LTD cavity performance. The voltage adder experiments with a series of double sized cavities (1 MA, ±100  kV will be reported in future publications.

[Herbological studies on Chinese crude drug Ma-huang. Part 1-On the botanical origin of Ma-huang in ancient China and the origin of Japanese Ma-huang].

Science.gov (United States)

Yoshizawa, Chieko; Kitade, Makiko; Mikage, Masayuki

2005-01-01

The botanical origin of a Chinese crude drug Ma-huang in ancient China and the origin of Japanese Ma-huang were herbologically studied. The results showed that the plants of Ephedra sinica Stapf, E. intermedia Schrenk & C. A. Meyer and E. equisetina Bunge were used as Ma-huang in China, and the first species was considered to be of high quality. The characters of Mao-zhou Ma-huang and Tong-zhou Ma-huang printed in Tu-jing-ben-cao, published in the Song Dynasty in China, were identified as E. likiangensis Florin and E. intermedia, respectively, and both species were recognized as excellent Ma-huang in the Ming Dynasty. The word origin of Katsune-kusa, the Japanese name for Ma-huang in the Heian Era, was etymologically considered as meaning the plant having reddish brown roots. In Japan, the plant of Equisetum ramosissimum Desf. var.japonicum Milde, of the family Equisetaceae, was substituted for Ma-huang in the middle of Edo Era, and it was designated that this action was based on the confusion of Ephedra plants and Equisetum plants those days in China.

PBFA Z: A 60-TW/5-MJ Z-pinch driver

International Nuclear Information System (INIS)

Spielman, R.B.; Deeney, C.; Chandler, G.A.; Douglas, M.R.; Fehl, D.L.; Matzen, M.K.; McDaniel, D.H.; Nash, T.J.; Porter, J.L.; Sanford, T.W.; Seamen, J.F.; Stygar, W.A.; Struve, K.W.; Breeze, S.P.; McGurn, J.S.; Torres, J.A.; Zagar, D.M.; Gilliland, T.L.; Jobe, D.O.; McKenney, J.L.; Mock, R.C.; Vargas, M.; Wagoner, T.; Peterson, D.L.

1997-01-01

PBFA Z, a new 60-TW/5-MJ electrical accelerator located at Sandia National Laboratories, is now the world's most powerful z-pinch driver. PBFA Z stores 11.4 MJ in its 36 Marx generators, couples 5 MJ into a 60-TW/105-ns FWHM pulse to the 120-mΩ water transmission lines, and delivers 3.0 MJ and 50 TW of electrical energy to the z-pinch load. Depending on load parameters, we attain peak load currents of 16-20 MA with a current rise time of ∼105ns with wire-array z-pinch loads. We have extended the x-ray performance of tungsten wire-array z pinches from earlier Saturn experiments. Using a 2-cm-radius, 2-cm-long tungsten wire array with 240, 7.5-μm diameter wires (4.1-mg mass), we achieved an x-ray power of 210 TW and an x-ray energy of 1.9 MJ. Preliminary spectral measurements suggest a mostly optically-thick, Planckian-like radiator below 1000 eV. Data indicate ∼100kJ of x rays radiated above 1000 eV. An intense z-pinch x-ray source with an overall coupling efficiency greater than 15% has been demonstrated. copyright 1997 American Institute of Physics

Fabrication of the vacuum vessel for JT-60 machine upgrade

International Nuclear Information System (INIS)

Uchikawa, T.; Takanabe, K.; Tsujimura, S.; Ue, K.; Oka, K.; Kuri, S.; Ioki, K.; Namiki, K.; Suzuki, Y.; Horliike, H.; Ninomiya, H.; Yamamoto, M.; Neyatani, Y.; Ando, T.; Matsukawa, M.

1992-01-01

The JT-60 tokamak was upgraded to double the plasma current to 6 MA. In the JT-60 machine upgrade (JT-60U), the vacuum vessel and poloidal field (PF) coils were renewed. The new vacuum vessel features a three-dimensionally curved, thin double-skin torus with multi-arc D-shaped cross section. The double-skin structure is strengthened with square pipes placed in between the outer and inner skins. Fabrication and site installation of the vessel was smoothly completed in February, 1991. This paper describes an overview of the JT-60U vacuum vessel construction

40Ar/39Ar dating of the Mumbai tholeiites and Panvel flexure: intense 62.5 Ma onshore-offshore Deccan magmatism during India-Laxmi Ridge-Seychelles breakup

Science.gov (United States)

Pande, Kanchan; Yatheesh, Vadakkeyakath; Sheth, Hetu

2017-08-01

Mumbai, located on the western Indian continental margin, exposes Danian-age Deccan magmatic units of diverse compositions, dipping seaward due to the Panvel flexure. The Ghatkopar-Powai tholeiitic sequence contains seaward-dipping (thus pre-flexure) flows and subvertical (thus post-flexure) dykes. We present new 40Ar/39Ar ages of 62.4 ± 0.7 and 62.4 ± 0.3 Ma (2σ) on two flows, and 62.2 ± 0.3, 62.8 ± 0.3 and 61.8 ± 0.2 Ma on three dykes, showing that this sequence is much younger than the main 66-65 Ma Deccan sequence in the Western Ghats escarpment. The mutually indistinguishable ages of the Ghatkopar-Powai tholeiites overlap with available 40Ar/39Ar ages of 62.6 ± 0.6 and 62.9 ± 0.2 Ma for the seaward-dipping Dongri rhyolite flow and 62.2 ± 0.6 Ma for the Saki Naka trachyte intrusion, both from the uppermost Mumbai stratigraphy. The weighted mean of these eight 40Ar/39Ar ages is 62.4 ± 0.1 Ma (2 SEM), relative to an MMhb-1 monitor age of 523.1 ± 2.6 Ma (2σ), and indicates essentially contemporaneous volcanism, intrusion and tectonic flexure. This age also coincides with the rift-to-drift transition of the Seychelles and Laxmi Ridge-India breakup and the emplacement of the Raman-Panikkar-Wadia seamount chain in the axial part of the Laxmi Basin. Pre-rift magmatism is seen in the 64.55 Ma Jogeshwari basalt in Mumbai and 63.5-63.0 Ma intrusions in the Seychelles. Post-rift magmatism is seen in the 60.8-60.9 Ma Manori trachyte and Gilbert Hill basalt intrusions in Mumbai and 60-61 Ma syenitic intrusions in the Seychelles. The Mumbai area thus preserves the pre-, syn- and post-rift onshore tectonomagmatic record of the breakup between the Seychelles and the Laxmi Ridge-India. Voluminous submarine volcanism forming the Raman, Panikkar and Wadia seamounts in the Laxmi Basin represents the offshore syn-rift magmatism.

Anti Ma2-associated myeloradiculopathy: expanding the phenotype of anti-Ma2 associated paraneoplastic syndromes

OpenAIRE

Murphy, Sinead M; Khan, Usman; Alifrangis, Constantine; Hazell, Steven; Hrouda, David; Blake, Julian; Ball, Joanna; Gabriel, Carolyn; Markarian, Pierre; Rees, Jeremy; Karim, Abid; Seckl, Michael J; Lunn, Michael P; Reilly, Mary M

2011-01-01

Anti-Ma2 associated paraneoplastic syndrome usually presents as limbic encephalitis in association with testicular tumours.1, 2 Only four patients have been reported with involvement outside the CNS, two of whom also had limbic or brainstem encephalitis.2, 3 We report a man with anti- Ma2 associated myeloradiculopathy and previous testicular cancer whose neurological syndrome stabilised and anti-Ma2 titres fell following orchidectomy of a microscopically normal testis.

Religiosidade popular: Reisado em Balsas (MA, uma experiência do sagrado

Directory of Open Access Journals (Sweden)

Raimundo Rajobac

2011-03-01

Full Text Available

6.0pt; line-height: normal;">O trabalho tem como objetivo apresentar uma leitura do Reisado em Balsas (MA, a partir do que nos propõe o método da Fenomenologia da Religião. Procuraremos identificar no Reisado, em sua estrutura e forma de expressão, os elementos que justifiquem a dimensão religiosa do ser humano. Para uma melhor observação e descrição desse fenômeno, e de sua forma de expressão, servirmo-nos de uma pesquisa de campo realizada em dezembro de 2005 a janeiro de 2006, o qual comporta os preparativos e realização da Festa dos Santos Reis, na região de Balsas (MA.

Operational characteristics of a 100-mA, 2-MeV radio-frequency quadrupole

International Nuclear Information System (INIS)

Johnson, K.F.; Cottingame, W.B.; Bolme, G.O.; Fortgang, C.M.; Ingalls, W.B.; Marquardt, J.; Rusthoi, D.P.; Sander, O.R.; Smith, M.; Worth, G.T.

1993-01-01

A 100-mA, 2.07-MeV Radio-Frequency Quadrupole (RFQ III) has been commissioned and operated routinely on the Accelerator Test Stand (ATS) [1] at Los Alamos National Laboratory. To characterize the RFQ output beam dynamics, measurements were made of the beam transmission and of the transverse and longitudinal phase-space distributions. Data were taken for different RFQ III operating conditions and compared to simulations

Sandia National Laboratories

Data.gov (United States)

Federal Laboratory Consortium — For more than 60 years, Sandia has delivered essential science and technology to resolve the nation's most challenging security issues.Sandia National Laboratories...

Identification and characterization of novel NuMA isoforms

Energy Technology Data Exchange (ETDEWEB)

Wu, Jin, E-mail: petersdu2112@hotmail.com [Key Laboratory for Cell Proliferation and Regulation of the Ministry of Education, Beijing Normal University, Beijing (China); Xu, Zhe [Department of Clinical Laboratory Diagnosis, Beijing Tiantan Hospital, Capital Medical University, Beijing (China); Core Laboratory for Clinical Medical Research, Beijing Tiantan Hospital, Capital Medical University, Beijing (China); He, Dacheng [Key Laboratory for Cell Proliferation and Regulation of the Ministry of Education, Beijing Normal University, Beijing (China); Lu, Guanting, E-mail: guantlv@126.com [Beijing DnaLead Science and Technology Co., LTD, Beijing (China)

2014-11-21

Highlights: • Seven NuMA isoforms generated by alternative splicing were categorized into 3 groups: long, middle and short. • Both exons 15 and 16 in long NuMA were “hotspot” for alternative splicing. • Lower expression of short NuMA was observed in cancer cells compared with nonneoplastic controls. • Distinct localization pattern of short isoforms indicated different function from that of long and middle NuMA. - Abstract: The large nuclear mitotic apparatus (NuMA) has been investigated for over 30 years with functions related to the formation and maintenance of mitotic spindle poles during mitosis. However, the existence and functions of NuMA isoforms generated by alternative splicing remains unclear. In the present work, we show that at least seven NuMA isoforms (categorized into long, middle and short groups) generated by alternative splicing from a common NuMA mRNA precursor were discovered in HeLa cells and these isoforms differ mainly at the carboxyl terminus and the coiled-coil domains. Two “hotspot” exons with molecular mass of 3366-nt and 42-nt tend to be spliced during alternative splicing in long and middle groups. Furthermore, full-length coding sequences of long and middle NuMA obtained by using fusion PCR were constructed into GFP-tagged vector to illustrate their cellular localization. Long NuMA mainly localized in the nucleus with absence from nucleoli during interphase and translocated to the spindle poles in mitosis. Middle NuMA displayed the similar cell cycle-dependent distribution pattern as long NuMA. However, expression of NuMA short isoforms revealed a distinct subcellular localization. Short NuMA were present in the cytosol during the whole cycle, without colocalization with mitotic apparatus. These results have allowed us tentatively to explore a new research direction for NuMA’s various functions.

The Ultrachopper tip: a wound temperature study.

Science.gov (United States)

Barlow, William R; Pettey, Jeff; Olson, Randall J

2013-12-01

To determine the thermal characteristics of the Ultrachopper and its thermal properties in varied viscosurgical substances. Experimental study. Not applicable. The Ultrachopper (Alcon, Inc) tip with the Infiniti (Alcon, Inc) handpiece was attached to a thermistor and placed in a test chamber filled with either an ophthalmic viscosurgical device (OVD) or balanced salt solution (BSS). The thermistor allowed for continuous monitoring of temperature from baseline and the change that occurred over 60 seconds of continuous run time. Mean maximum temperature in each OVD exceeded 50°C over the first 25 seconds of continuous run time. The mean maximum temperature was statistically significantly higher with all OVDs (p < 0.0001) when compared with BSS. A small but statistically significant difference in mean maximum temperature was shown between Healon 5 (AMO, Inc) and Viscoat (Alcon, Inc) (p < 0.05). The linear increase in temperature was statistically significantly different with all OVDs compared with BSS (p < 0.0001). The thermal properties of the Ultrachopper tip demonstrate a heat-generating capacity that achieves published thresholds for risk for wound burn. Copyright © 2013 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

Investigation of the production of cobalt-60 via particle accelerator

Directory of Open Access Journals (Sweden)

Artun Ozan

2017-01-01

Full Text Available The production process of cobalt-60 was simulated by a particle accelerator in the energy range of 5 to 100 MeV, particle beam current of 1 mA, and irradiation time of 1 hour to perform yield, activity of reaction, and integral yield for charged particle-induced reactions. Based on nuclear reaction processes, the obtained results in the production process of cobalt-60 were also discussed in detail to determine appropriate target material, optimum energy ranges, and suitable reactions.

The (mis)Measurement of M&A Performance

DEFF Research Database (Denmark)

Meglio, Olimpia; Risberg, Annette

2011-01-01

This paper seeks to further the understanding of the variety of meanings M&A scholars attach to the label “M&A performance” by providing an alternative way to interpret the claimed inconsistency of M&A research findings. While many scholars contend that the problem stems from the multiplicity of M......&A performance measures, we believe the problem rests in trying to compare different measures as if they were measuring the same feature of the organization. Through our narrative review of empirical research we analyze factors shaping the M&A – as well as the organizational – performance measurement process....... The conclusion is that it is not possible to talk about M&A performance as if it was a universal construct....

Maïs beperkt nitraatverlies van gras

NARCIS (Netherlands)

Verloop, J.; Boumans, L.

2006-01-01

Maïs staat bekend als een gewas dat veel nitraat naar het grondwater lekt. Maar maïs heeft ook goeie kanten. Nieuw in dit rijtje is dat maïs, in vruchtwisseling met gras, ook het nitraatverlies van grasland beperkt. Dit blijkt uit de metingen van het RIVM op De Marke.

Comparison of torsional and microburst longitudinal phacoemulsification: a prospective, randomized, masked clinical trial.

Science.gov (United States)

Vasavada, Abhay R; Raj, Shetal M; Patel, Udayan; Vasavada, Vaishali; Vasavada, Viraj

2010-01-01

To compare intraoperative performance and postoperative outcome of three phacoemulsification technologies in patients undergoing microcoaxial phacoemulsification through 2.2-mm corneal incisions. The prospective, randomized, single-masked study included 360 eyes randomly assigned to torsional (Infiniti Vision System; Alcon Laboratories, Fort Worth, TX), microburst with longitudinal (Infiniti), or microburst with longitudinal (Legacy Everest, Alcon Laboratories) ultrasound. Assessments included surgical clock time, fluid volume, and intraoperative complications, central corneal thickness on day 1 and months 1 and 3 postoperatively, and endothelial cell density at 3 months postoperatively. Comparisons among groups were conducted. Torsional ultrasound required significantly less surgical clock time and fluid volume than the other groups. There were no intraoperative complications. Change in central corneal thickness and endothelial cell loss was significantly lower in the torsional ultrasound group at all postoperative visits (P < .001, Kruskal-Wallis test) compared to microburst longitudinal ultrasound modalities. Torsional ultrasound demonstrated quantitatively superior intraoperative performance and showed less increase in corneal thickness and less endothelial cell loss compared to microburst longitudinal ultrasound. Copyright 2010, SLACK Incorporated.

Reconstruction of Northeast Asian Deformation Integrated with Western Pacific Plate Subduction since 200 Ma

Science.gov (United States)

Liu, S.; Gurnis, M.; Ma, P.; Zhang, B.

2017-12-01

The configuration and kinematics of continental deformation and its marginal plate tectonics on the Earth's surface are intrinsic manifestations of plate-mantle coupling. The complex interactions of plate boundary forces result in plate motions that are dominated by slab pull and ridge push forces and the effects of mantle drag; these interactions also result in continental deformation with a complex basin-mountain architecture and evolution. The kinematics and evolution of the western Pacific subduction and northeast Asian continental-margin deformation are a first-order tectonic process whose nature and chronology remains controversial. This paper implements a "deep-time" reconstruction of the western Pacific subduction, continental accretion or collision and basin-mountain deformation in northeast Asia since 200 Ma based on a newly revised global plate model. The results demonstrate a NW-SE-oriented shortening from 200-137 Ma, a NWW-SEE-oriented extension from 136-101 Ma, a nearly N-S-oriented extension and uplift with a short-term NWW-SEE-oriented compressional inversion in northeast China from 100-67 Ma, and a NW-SE- and nearly N-S-oriented extension from 66 Ma to the present day. The western Pacific oceanic plate subducted forward under East Asia along Mudanjiang-Honshu Island during the Jurassic, and the trenches retreated to the Sikhote-Alin, North Shimanto, and South Shimanto zones from ca. 137-128 Ma, ca. 130-90 Ma, and in ca. 60 Ma, respectively. Our time-dependent analysis of plate motion and continental deformation coupling suggests that the multi-plate convergent motion and ocean-continent convergent orogeny were induced by advance subduction during the Jurassic and earliest Cretaceous. Our analysis also indicates that the intra-continent rifting and back-arc extension were triggered by trench retreat during the Cretaceous and that the subduction of oceanic ridge and arc were triggered by trench retreat during the Cenozoic. Therefore, reconstructing

75 FR 51460 - Novartis AG; Analysis of Proposed Agreement Containing Consent Orders to Aid Public Comment

Science.gov (United States)

2010-08-20

... of a controlling interest in Alcon, Inc. (``Alcon'') from Nestle, S.A. The proposed Consent Agreement..., Novartis proposes to acquire all of the outstanding shares of Alcon held by Nestle in a transaction valued... pharmaceuticals headquartered in Basel, Switzerland. Nestle is the world's largest food company, and is...

European Fiber Optics. USAF Laboratory Experts’ Visit,

Science.gov (United States)

1979-12-01

emitting at 480 ma. AE-Telefunken Telecomunications and Cable Systems Division Postfach 1120 7150 Backnang, Germany Principal Contact: Dr. K. D. 4chenkel...alignment purposes. Standard Telecomunication Laboratories, Inc. (STL) London Road Harlow, Essex 017 9NA, England Principal Contact: Dr. M. Chown - Manager

Isolation of MA-ACS Gene Family and Expression Study of MA-ACS1 Gene in Musa acuminata Cultivar Pisang Ambon Lumut

Directory of Open Access Journals (Sweden)

LISTYA UTAMI KARMAWAN

2009-03-01

Full Text Available Musa acuminata cultivar pisang ambon lumut is a native climacteric fruit from Indonesia. Climacteric fruit ripening process is triggered by the gaseous plant hormone ethylene. The rate limiting enzyme involved in ethylene biosynthesis is ACC synthase (ACS which is encoded by ACS gene family. The objective of this study is to identify MA-ACS gene family in M. acuminata cultivar pisang ambon lumut and to study the MA-ACS1 gene expression. The result showed that there were nine M. acuminata ACS gene family members called MA-ACS1–9. Two of them (MA-ACS1 and MA-ACS2 were assessed using reverse transcriptase PCR (RT-PCR for gene expression study and it was only MA-ACS1 correlated with fruit ripening. The MA-ACS1 gene fragment has been successfully isolated and characterized and it has three introns, four exons, and one stop codon. It also shows highest homology with MACS1 gene from M. acuminata cultivar Hsian Jien Chiao (GenBank accession number AF056164. Expression analysis of MA-ACS1 using quantitative PCR (qPCR showed that MA-ACS1 gene expression increased significantly in the third day, reached maximum at the fifth day, and then decreased in the seventh day after harvesting. The qPCR expression analysis result correlated with the result of physical analysis during fruit ripening.

Stormwater Pollution Prevention Plan for the TA-60-02 Salvage Warehouse, Los Alamos National Laboratory, Revision 3, January 2018

Energy Technology Data Exchange (ETDEWEB)

Burgin, Jillian Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2018-02-08

This Storm Water Pollution Prevention Plan (SWPPP) was developed in accordance with the provisions of the Clean Water Act (33 U.S.C. §§1251 et seq., as amended), and the Multi-Sector General Permit for Storm Water Discharges Associated with Industrial Activity (U.S. EPA, June 2015) issued by the U.S. Environmental Protection Agency (EPA) for the National Pollutant Discharge Elimination System (NPDES) and using the industry specific permit requirements for Sector P-Land Transportation and Warehousing as a guide. The applicable stormwater discharge permit is EPA General Permit Registration Number NMR053915 (Los Alamos National Security (LANS) (U.S. EPA, June 2015). Contents of the June 4, 2015 Multi-sector General Permit can be viewed at: https://www.epa.gov/sites/production/files/2015- 10/documents/msgp2015_finalpermit.pdf This SWPPP applies to discharges of stormwater from the operational areas of the TA-60-02 Salvage and Warehouse facility at Los Alamos National Laboratory. Los Alamos National Laboratory (also referred to as LANL or the “Laboratory”) is owned by the Department of Energy (DOE), and is operated by Los Alamos National Security, LLC (LANS). Throughout this document, the term “facility” refers to the TA-60-02 Salvage/ Warehouse and associated areas. The current permit expires at midnight on June 4, 2020. A copy of the facility NOI and LANS Delegation of Authority Letter are located in Appendix C of this SWPPP.

Evaluation of rotation and visual outcomes after implantation of monofocal and multifocal toric intraocular lenses.

Science.gov (United States)

Garzón, Nuria; Poyales, Francisco; de Zárate, Begoña Ortíz; Ruiz-García, Jose Luis; Quiroga, Juan Antonio

2015-02-01

To evaluate rotational stability and its influence on postoperative visual acuity of different monofocal and multifocal toric intraocular lenses (IOLs). A prospective interventional study was designed. Ninety-one patients with a mean age of 71.65 ± 11.82 years were implanted with toric IOLs after phacoemulsification. Three monofocal toric IOLs (the Lentis LT [Oculentis, Berlin, Germany], enVista [Bausch & Lomb, Rochester, NY], and AcrySof IQ [Alcon Laboratories, Inc., Fort Worth, TX]) and one multifocal toric IOL (AcrySof IQ ReSTOR; Alcon Laboratories, Inc.) were implanted. Preoperative and postoperative images were taken to calculate the misalignment due to the marking method. To evaluate rotation in the different follow-up visits, another photograph was taken 1 hour and 1, 7 and 30 days postoperatively. Refraction, uncorrected distance visual acuity (UDVA), and corrected distance visual acuity were measured 30 days postoperatively. Postoperative UDVA was 0.1 logMAR or better in 64.6% of eyes implanted with monofocal IOLs and 46.4% of eyes implanted with multifocal IOLs. The enVista toric IOL showed the best UDVA compared to the other monofocal IOLs, with 81% of eyes with 0.1 logMAR or better. The mean misalignment in the total group studied was 0.07° ± 0.60°; 69.6% of monofocal IOLs and 67.9% of multifocal IOLs showed less than 5° of rotation. A correlation was found between postoperative UDVA and rotation in the monofocal and multifocal IOLs implanted (r = 0.439 [P < .011] and = 0.787 [P = .001], respectively). At 1 month postoperatively, UDVA was slightly more affected by IOL rotation in multifocal than monofocal toric IOLs. The marking method was also effective. Copyright 2015, SLACK Incorporated.

The Banana Fruit SINA Ubiquitin Ligase MaSINA1 Regulates the Stability of MaICE1 to be Negatively Involved in Cold Stress Response.

Science.gov (United States)

Fan, Zhong-Qi; Chen, Jian-Ye; Kuang, Jian-Fei; Lu, Wang-Jin; Shan, Wei

2017-01-01

The regulation of ICE1 protein stability is important to ensure effective cold stress response, and is extensively studied in Arabidopsis . Currently, how ICE1 stability in fruits under cold stress is controlled remains largely unknown. Here, we reported the possible involvement of a SEVEN IN ABSENTIA (SINA) ubiquitin ligase MaSINA1 from banana fruit in affecting MaICE1 stability. MaSINA1 was identified based on a yeast two-hybrid screening using MaICE1 as bait. Further yeast two-hybrid, pull-down, bimolecular fluorescence complementation (BiFC) and co-immunoprecipitation (CoIP) assays confirmed that MaSINA1 interacted with MaICE1. The expression of MaSINA1 was repressed by cold stress. Subcellular localization analysis in tobacco leaves showed that MaSINA1 was localized predominantly in the nucleus. In vitro ubiquitination assay showed that MaSINA1 possessed E3 ubiquitin ligase activity. More importantly, in vitro and semi- in vivo experiments indicated that MaSINA1 can ubiquitinate MaICE1 for the 26S proteasome-dependent degradation, and therefore suppressed the transcriptional activation of MaICE1 to MaNAC1, an important regulator of cold stress response of banana fruit. Collectively, our data reveal a mechanism in banana fruit for control of the stability of ICE1 and for the negative regulation of cold stress response by a SINA E3 ligase via the ubiquitin proteasome system.

Adole, MA

African Journals Online (AJOL)

Adole, MA. Vol 4, No 1 (2011) - Articles Effects of Groundnut Husk Ash-blended Cement on Chemical Resistance of Concrete Abstract PDF. ISSN: 1596-6035. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

Preliminary experiments to estimate the PE.MA.M (PElagic MArine Mesocosm) offshore behaviour

Science.gov (United States)

Albani, Marta; Piermattei, Viviana; Stefanì, Chiara; Marcelli, Marco

2016-04-01

The phytoplankton community is controlled not only by local environmental conditions but also by physical processes occurring on different temporal and spatial scales. Hydrodynamic local conditions play an important role in marine ecosystems. Several studies have shown that hydrodynamic conditions can influence the phytoplankton settling velocity, vertical and horizontal distribution and formation of cyanobacterial blooms. Mesocosms are useful structures to simulate marine environment at mesoscale resolution; allowing to closely approximate biotic or abiotic parameters of interest directly in nature. In this work an innovative structure named PE.MA.M (PElagic MArine Mesocosm) is presented and tested. Laboratory experiments have been conducted in order to observe seasonal variations of biomass behaviour in two different hydrodynamic conditions: outside as well as whithin the PE.MA.M. We have evaluated whether it is possible to isolate a natural system from external water mass hydrodynamic exchanges and to assume that phytoplankton cells' transition is limited at the net and sea interface. Preliminary experiments test the isolating capacity of the net, to determine the currents' attenuation rate and to estimate the possible PE.MA.M. offshore behaviour. In the first investigation, we monitored the diffusion of phytoplankton cells. The PE.MA.M. exterior and interior were simulated using a plexiglass tank divided into two half-tanks (Aout-Bin) by a septum consisting of a net like a PE.MA.M. The tank was filled up with 10 L of water and only the half-tank Aout was filled up with 10 ml of phytoplankton culture (Clorella sp.). We monitored the chlorophyll concentrations for 24 hours. The two tanks had similar concentrations after 4 hours (2.70322 mg/m³ Aout and 2.37245 mg/m3 Bin) and this constant relationship was maintened until the end of the test. In the second investigation we used clod cards to measure water motions.We conducted two experiments within tank, the first

Review of JT-60 experimental results from June to October, 1987

International Nuclear Information System (INIS)

1988-03-01

This is a prompt report on JT-60 experimental results from June to October, 1987. Experiments in hydrogen plasmas have been undertaken with up to 3.2 MA of plasma current in limiter discharges, 2.7 MA in divertor discharges, and 30 MW of total NB (H 0 → H + ) and RF injection power. In limiter discharges with ∼3 MA plasma current, the maximum central electron density of 1.3 x 10 20 m -3 and the energy confinement time of 0.15 - 0.18 sec were obtained with heating powers of 13 - 20 MW. The total plasma stored energy of 3.1 MJ, and n e (0)τ E of 1.4 - 1.8 x 10 19 m -3 sec were achieved. The best set of parameters achieved is n e (0)τ E = 1.8 x 10 19 m -3 sec and T i (0) = 3.7 KeV at plasma current of 3.2 MA. By applying deutrium discharge condition, n e (0)τ E and T i (0) enter the JT-60 target area determined by Atomic Energy Commission. Many short periods (50 - 100 ms) of H-mode phase are found in outside X-point divertor discharges with NB or NB + RF (LH or IC) heating power of more than 16 MW, although at present the energy confinement improvement is limited to within 10 %. In combined LH and NB heating of low-n-bar e discharge, the plasma stored energy increases with the same rate as NB heating only, with preferential absorption of LH wave to the high energy beam ions. In combined NB and on-axis ICRF heating of low-n-bar e discharge, a high incremental energy confinement time is obtained, with strong high energy beam ion acceleration and electron heating in the central region of the plasma. (author)

Study of particle pumping characteristics for different pumping geometries in JT-60U and DIII-D divertors

International Nuclear Information System (INIS)

Takenaga, H.; Sakasai, A.; Kubo, H.

2001-01-01

Particle pumping characteristics were compared between pumping from the inner side private flux region (IPP) and pumping from both sides of the private flux region (BPP) in the JT-60U W shaped divertor, and between JT-60U IPP and pumping in the DIII-D lower baffled divertor. The pumping flux for BPP is smaller than that for IPP by about a factor of 2 with weak in-out asymmetry of recycling neutral flux and by a factor of 3.5-6.5 with strong in-out asymmetry. The reduction of the pumping flux for BPP is consistent with Monte Carlo simulations, where backflow at the outer pumping slot is observed due to in-out recycling asymmetry. The pumping flux in DIII-D at I p =0.8 MA and B T =1.6 T is comparable to or smaller than that for JT-60U IPP at I p =1.0 MA, B T =3.8 T and I p =1.5 MA, B T =3.5 T in the same density regime. In the DIII-D divertor with pumping from the private flux region, the pumping flux decreases with increasing in-out asymmetry. The pumping flux normalized by the integrated D α emission over the whole plasma exhibits a similar dependence on the distance between the pumping slot and the strike point in JT-60U IPP and the DIII-D lower divertor with pumping through the outer divertor plasma region. (author)

FuSuMaTech workshop

CERN Multimedia

Olofsson, Simon

2018-01-01

The goal of the FuSuMaTecH IP workshop, organised at CERN Ideaquare 19-20 April, was to educate superconductivity and magnet experts about intellectual property. About 30 participants from multiple institutes and companies worked together in this two day interactive program which was facilitated by CERN Knowledge Transfer. Great progress was made in shaping the FuSuMaTech industrial demonstrator projects as well as the R&D&I subjects.

Phengaris (Maculinea) alcon

NARCIS (Netherlands)

Wynhoff, I.; Bakker, R.B.; Oteman, B.; Seixas Arnaldo, .P.; van Langevelde, F.

2015-01-01

1.The survival of eggs and larvae is dependent on the oviposition site selection of their mothers. In obligate myrmecophilic butterflies, both host plant phenology and host ant presence are expected to affect the decision where to deposit eggs. The importance of ant nest presence in the oviposition

PBFA Z: A 20-MA z-pinch driver for plasma radiation sources

International Nuclear Information System (INIS)

Spielman, R.B.; Breeze, S.F.; Deeney, C.

1996-01-01

Sandia National Laboratories is completing a major modification to the PBFA-II facility. PBFA Z will be a z-pinch driver capable of delivering up to 20 MA to a z-pinch load. It optimizes the electrical coupling to the implosion energy of z pinches at implosion velocities of ∼ 40 cm/μs. Design constraints resulted in an accelerator with a 0.12-Ω impedance, a 10.25-nH inductance, and a 120-ns pulse width. The design required new water transmission lines, insulator stack, and vacuum power feeds. Current is delivered to the z-pinch load through four, self-magnetically-insulated vacuum transmission lines and a double post-hole convolute. A variety of design codes are used to model the power flow. These predict a peak current of 20 MA to a z-pinch load having a 2-cm length, a 2-cm radius, and a 15--mg mass, coupling 1.5 MJ into kinetic energy. We present 2-D Rad-Hydro calculations showing MJ x-ray outputs from tungsten wire-array z pinches

PBFA Z: A 20-MA Z-pinch driver for plasma radiation sources

International Nuclear Information System (INIS)

Spielman, R.B.; Breeze, S.F.; Deeney, C.

1996-01-01

Sandia National Laboratories is completing a major modification to the PBFA-II facility. PBFA Z will be capable of delivering up to 20 MA to a z-pinch load. It optimizes the electrical coupling to the implosion energy of z pinches at implosion velocities of ∼ 40 cm/μs. Design constraints resulted in an accelerator with a 0.12-Ω impedance, a 10.25-nH inductance, and a 120-ns pulse width. The design required new water transmission lines, insulator stack, and vacuum power feeds. Current is delivered to the z-pinch load through four self-magnetically-insulated vacuum transmission lines and a double post-hole convolute. A variety of design codes are used to model the power flow. These predict a peak current of 20 MA to a z-pinch load having a 2-cm length, a 2-cm radius, and a 15-mg mass, coupling 1.5 MJ into kinetic energy. Calculations are presented showing MJ x-ray outputs from tungsten wire-array z pinches. (author). 4 figs., 14 refs

PBFA Z: A 20-MA Z-pinch driver for plasma radiation sources

Energy Technology Data Exchange (ETDEWEB)

Spielman, R B; Breeze, S F; Deeney, C [Sandia Labs., Albuquerque, NM (United States); and others

1997-12-31

Sandia National Laboratories is completing a major modification to the PBFA-II facility. PBFA Z will be capable of delivering up to 20 MA to a z-pinch load. It optimizes the electrical coupling to the implosion energy of z pinches at implosion velocities of {approx} 40 cm/{mu}s. Design constraints resulted in an accelerator with a 0.12-{Omega} impedance, a 10.25-nH inductance, and a 120-ns pulse width. The design required new water transmission lines, insulator stack, and vacuum power feeds. Current is delivered to the z-pinch load through four self-magnetically-insulated vacuum transmission lines and a double post-hole convolute. A variety of design codes are used to model the power flow. These predict a peak current of 20 MA to a z-pinch load having a 2-cm length, a 2-cm radius, and a 15-mg mass, coupling 1.5 MJ into kinetic energy. Calculations are presented showing MJ x-ray outputs from tungsten wire-array z pinches. (author). 4 figs., 14 refs.

Upbeat nystagmus in anti-Ma2 encephalitis.

Science.gov (United States)

Garcia-Reitboeck, Pablo; Thompson, Graham; Johns, Paul; Al Wahab, Yasir; Omer, Salah; Griffin, Colette

2014-02-01

Anti-Ma2 encephalitis is a paraneoplastic disorder characterised by brainstem and/or limbic involvement. Eye movement abnormalities can occur in this condition, often with confusion or somnolence. We describe a patient with progressive oscillopsia (with upbeat nystagmus) and unsteadiness, followed by acute pancreatitis. She did not respond to immunomodulatory treatment and subsequently died of complications related to pancreatitis and sepsis. There was no tumour identified at autopsy, but the anti-Ma2 antibodies in her serum and the discovery of a brainstem-predominant inflammatory infiltrate at autopsy strongly suggest a paraneoplastic disorder. Our case illustrates that upbeat nystagmus can be a predominant feature in anti-Ma2 encephalitis; clinicians should consider testing for anti-Ma2 antibodies in patients with upbeat nystagmus of unknown cause.

Molecular and clinical diversity in paraneoplastic immunity to Ma proteins.

Science.gov (United States)

Rosenfeld, M R; Eichen, J G; Wade, D F; Posner, J B; Dalmau, J

2001-09-01

Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. Preliminary studies suggested the existence of other Ma proteins and different patterns of immune response associated with distinct neurologic symptoms and cancers. In this study, our aim was to isolate the full-length sequence of Ma2 and new family members, identify the major autoantigen of the disorder, and extend the dinical-immunological analysis to 29 patients. Sera from selected patients were used to probe a brainstem cDNA library and isolate the entire Ma2 gene and a new family member, Ma3. Ma3 mRNA is ubiquitously expressed in brain, testis, and several systemic tissues. The variable cellular expression of Ma proteins and analysis of protein motifs suggest that these proteins play roles in the biogenesis of mRNA. Immunoblot studies identify Ma2 as the major autoantigen with unique epitopes recognized by all patients' sera. Eighteen patients had antibodies limited to Ma2: they developed limbic, hypothalamic, and brainstem encephalitis, and 78% had germ-cell tumors of the testis. Eleven patients had antibodies to Ma2 and additional antibodies to Ma1 and/or Ma3; they usually developed additional cerebellar symptoms and more intense brainstem dysfunction, and 82% of these patients had tumors other than germ-cell neoplasms. Overall, 17 of 24 patients (71%) with brain magnetic resonance imaging studies had abnormalities within or outside the temporal lobes, some as contrast-enhancing nodular lesions. A remarkable finding of immunity to Ma proteins is that neurologic symptoms may improve or resolve. This improvement segregated to a group of patients with antibodies limited to Ma2.

Review of JT-60 experiment (April-June, 1985)

International Nuclear Information System (INIS)

1986-11-01

Initial ohmic heating experiments in JT-60 were performed for a three month period of April-June 1985. A maximum plasma current of 1.6 MA was obtained for both divertor and limiter discharges. Low-q discharges of q eff = 2.5 and high density discharges of 4.8 x 10 19 m -3 were obtained in the divertor configuration. Typical divertor actions, i.e. particle exhaust, heat exhaust, impurity reduction and remote radiative cooling were demonstrated. (author)

Does Uniformity of Topical Corticosteroid Ophthalmic Medications: Flourometholone Acetate 0.1 Suspension and Loteprednol Etabonate 0.5 gel

Science.gov (United States)

2017-01-03

following ocular surgery.1 They are available in different forms including emulsions , ointments, solutions, gels, and suspensions. The choice of...study done by Stringer and Bryant compared dose uniformity of difluprednate ophthalmic emulsion (Durezol®) with prednisolone acetate (brand name...topical ophthalmic corticosteroid suspensions. Am J Ophthalmol. 1979;87(2): 210- 214. 5 Flarex® [ package insert]. Fort Worth, TX: Alcon Laboratories Inc

Effect of bottle height and aspiration rate on postocclusion surge in Infiniti and Millennium peristaltic phacoemulsification machines.

Science.gov (United States)

Ward, Matthew S; Georgescu, Dan; Olson, Randall J

2008-08-01

To assess how flow and bottle height affect postocclusion surge in the Infiniti (Alcon, Inc.) and Millennium (Bausch & Lomb) peristaltic machines. John A. Moran Eye Center Clinical Laboratories, University of Utah, Salt Lake City, Utah. Postocclusion anterior chamber depth changes were measured in human eye-bank eyes using A-scan. Surge was simulated by clamping the aspiration tubing and releasing it at maximum vacuum. In both machines, surge was measured (1) with aspiration held constant at 12 mL/min and bottle heights at 60, 120, and 180 cm and (2) with bottle height held constant at 60 cm and aspiration rates at 12, 24, and 36 mL/min. Surge decreased approximately 40% with each 60 cm increase in bottle height in the Infiniti. It was constant at all bottle heights in the Millennium. At 12 and 24 mL/min aspiration rates, surge in the Millennium was less than half that in the Infiniti (PInfiniti system and was relatively constant with increasing bottle height in the Millennium system. The Millennium may offer a more stable phacoemulsification platform with respect to surge at a higher aspiration rate.

The evolution of the magmatic arc of Southern Peru (200-60 Ma), Arequipa area: insight from geochemical modeling

Science.gov (United States)

Demouy, S.; Benoit, M.; De Saint Blanquat, M.; Brunet, P.

2012-12-01

Cordilleran-type batholiths are built by prolonged arc activity along continental margins and may provide detailed magmatic records of the subduction system evolution. The magmas produced in subduction context involve both mantellic and crustal end members and are subject to various petrological processes. The MASH zones (Hildreth and Moorbath, 1988), at the basis of the continental crust, are the best places for the genesis of such hybrid magmas. The various geochemical signatures observed in the plutonic rocks, may also be attributed to source heterogeneities or generated by subsequent petrological processes. This study has focused in the Arequipa section of the Coastal Batholith of Southern Peru (200-60 Ma), in an area extending over 80x40 km. Major and trace elements as well as Sr and Nd isotopic analyses were performed in a set of 100 samples ranging from gabbro to granite. The obtained data highlight the wide heterogeneity of the geochemical signatures that is not related to the classification of the rocks. In first step, Rb/Sr systematic was used to isolate a set of samples plotting along a Paleocene isochron and defining a cogenetic suite. This suite appears to have evolved by simple fractional crystallization. By using reverse modeling, the parameters controlling the fractional crystallization process were defined, as partition coefficients, initial concentrations and amount of fractional crystallization. The other magmatic suites display a wide range of isotopic and geochemical signatures. To explain this heterogeneity, a model involving competition between fractional crystallization and magma mixing into MASH zones was proposed. A large range of hybrid magma types is potentially generated during the maturation of the system, but this range tends to disappear as fractionation and mixing occurs. Finally the model predicts the genesis of a homogeneous reservoir created at depth, from which magmas may evolve only by fractional crystallization. Therefore

Increase in physical activities in kindergarten children with cerebral palsy by employing MaKey-MaKey-based task systems.

Science.gov (United States)

Lin, Chien-Yu; Chang, Yu-Ming

2014-09-01

In this study, we employed Flash- and Scratch-based multimedia by using a MaKey-MaKey-based task system to increase the motivation level of children with cerebral palsy to perform physical activities. MaKey MaKey is a circuit board that converts physical touch to a digital signal, which is interpreted by a computer as a keyboard message. In this study, we used conductive materials to control this interaction. This study followed single-case design using ABAB models in which A indicated the baseline and B indicated the intervention. The experiment period comprised 1 month and a half. The experimental results demonstrated that in the case of two kindergarten children with cerebral palsy, their scores were considerably increased during the intervention phrases. The developmental applications of the results are also discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

Thermal study of bare tips with various system parameters and incision sizes.

Science.gov (United States)

Osher, Robert H; Injev, Valentine P

2006-05-01

To identify major and minor surgeon-controlled parameters that affect incision temperature when performing microincision lens removal using the Alcon Infiniti Vision System. In vitro research and development laboratory, Alcon Research, Irvine, California, USA. Phacoemulsification was performed in eye-bank cadaver eyes and the following parameters evaluated: incision, duty cycle, ultrasound (US) power, aspiration flow rate (AFR), vacuum, pulse, bottle height and balanced salt solution temperature, and tip design/size. Each parameter was varied while the others remained constant. The resulting temperature of the incision and US tip was measured using a thermal camera. Major contributors to elevated incision temperature included incision size, US power, duty cycle, AFR, vacuum setting, tip design, and presence of an ophthalmic viscosurgical device (OVD). Minor contributors included pulse frequency, bottle height, and temperature of the infusate. Microincision lens removal can be performed at safe temperatures with the knowledgeable selection of surgeon-controlled parameters.

MaRIE Undulator & XFEL Systems

Energy Technology Data Exchange (ETDEWEB)

Nguyen, Dinh Cong [Los Alamos National Laboratory; Marksteiner, Quinn R. [Los Alamos National Laboratory; Anisimov, Petr Mikhaylovich [Los Alamos National Laboratory; Buechler, Cynthia Eileen [Los Alamos National Laboratory

2015-03-23

The 22 slides in this presentation treat the subject under the following headings: MaRIE XFEL Performance Parameters, Input Electron Beam Parameters, Undulator Design, Genesis Simulations, Risks, and Summary It is concluded that time-dependent Genesis simulations show the MaRIE XFEL can deliver the number of photons within the required bandwidth, provided a number of assumptions are met; the highest risks are associated with the electron beam driving the XFEL undulator; and risks associated with the undulator and/or distributed seeding technique may be evaluated or retired by performing early validation experiments.

[Ma2 antibody and multiple mononeuropathies].

Science.gov (United States)

Ayrignac, X; Castelnovo, G; Landrault, E; Fayolle, H; Pers, Y-M; Honnorat, J; Campello, C; Figarella-Branger, D; Labauge, P

2008-01-01

Anti-Ma2 antibodies belong to a family of onconeuronal antibodies that target proteins expressed in brain, testis and several tumors. Previously observed in patients presenting with limbic encephalitis, they seem to be associated with several other paraneoplastic syndromes. We report the case of a 73-year-old woman presenting sensory and motor neuropathy associated with non-small-cell lung cancer who had Ma2-antibodies.

Comparative Study of Antibacterial and Antifungal Effects of Rigid Gas Permeable Contact Lens Disinfecting Solutions

OpenAIRE

Kuzman, Tomislav; Barišić Kutija, Marija; Kordić, Rajko; Popović Suić, Smiljka; Jandroković, Sonja; Škegro, Ivan; Pokupec, Rajko

2013-01-01

The aim of this study was to compare antimicrobial efficacy of rigid contact lens disinfecting solutions. We tested five commercially available solutions: Unique pH (Alcon Laboratories), Boston Advance (Polymer Technology Corp.), Nitilens Conditioner GP (Avizor), Total Care (AMO), Boston Simplus (Bausch&Lomb). Their efficacy to disinfect saline solution experimentally contaminated with American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922...

[Anti-Ma2-associated encephalitis and paraneoplastic limbic encephalitis].

Science.gov (United States)

Yamamoto, Tomotaka; Tsuji, Shoji

2010-08-01

Anti-Ma2-associated encephalitis (or anti-Ma2 encephalitis) is a paraneoplastic neurological syndrome (PNS) characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction. Anti-Ma2 antibodies detected in the serum or cerebrospinal fluid of patients are highly specific for this disease entity and belong to a group of well-characterized onconeuronal antibodies (or classical antibodies). The corresponding antigen, Ma2 is selectively expressed intracellularly in neurons and tumors as is the case with other onconeuronal antigens targeted by classical antibodies. However, in most cases the clinical pictures are different from those of classical PNS and this creates a potential risk of underdiagnosis. Although limbic dysfunction is the most common manifestation in patients with anti-Ma2 encephalitis which is one of the major causes of paraneoplastic limbic encephalitis (LE), it has been reported that less than 30% of the patients with anti-Ma2 LE exhibit clinical presentations typical of the classical description of LE. Of the remaining, many exhibit excessive daytime sleepiness, vertical ophthalmoparesis, or both associated with LE, because of frequent involvement of the diencephalon and/or upper brainstem. Anti-Ma2 LE can also be manifested as a pure psychiatric disturbance such as obsessive-compulsive disorder in a few cases. Some patients develop mesodiencephalic encephalitis with minor involvement of the limbic system, and some may manifest severe hypokinesis. About 40% of the patients with anti-Ma2 antibodies also have antibodies against different epitopes on Ma1, a homologue of Ma2. These patients may have predominant cerebellar and/or brainstem dysfunctions due to more extensive involvement of subtentorial structures. Anti-Ma2 encephalitis is outstanding among other PNS associated with classical antibodies in that the response rate to treatment is relatively high. While it can cause severe neurological deficits or death in a substantial

Hypocretin-1 CSF levels in anti-Ma2 associated encephalitis.

Science.gov (United States)

Overeem, S; Dalmau, J; Bataller, L; Nishino, S; Mignot, E; Verschuuren, J; Lammers, G J

2004-01-13

Idiopathic narcolepsy is associated with deficient hypocretin transmission. Narcoleptic symptoms have recently been described in paraneoplastic encephalitis with anti-Ma2 antibodies. The authors measured CSF hypocretin-1 levels in six patients with anti-Ma2 encephalitis, and screened for anti-Ma antibodies in patients with idiopathic narcolepsy. Anti-Ma autoantibodies were not detected in patients with idiopathic narcolepsy. Four patients with anti-Ma2 encephalitis had excessive daytime sleepiness; hypocretin-1 was not detectable in their cerebrospinal fluid, suggesting an immune-mediated hypocretin dysfunction.

PuMA: the Porous Microstructure Analysis software

Science.gov (United States)

Ferguson, Joseph C.; Panerai, Francesco; Borner, Arnaud; Mansour, Nagi N.

2018-01-01

The Porous Microstructure Analysis (PuMA) software has been developed in order to compute effective material properties and perform material response simulations on digitized microstructures of porous media. PuMA is able to import digital three-dimensional images obtained from X-ray microtomography or to generate artificial microstructures. PuMA also provides a module for interactive 3D visualizations. Version 2.1 includes modules to compute porosity, volume fractions, and surface area. Two finite difference Laplace solvers have been implemented to compute the continuum tortuosity factor, effective thermal conductivity, and effective electrical conductivity. A random method has been developed to compute tortuosity factors from the continuum to rarefied regimes. Representative elementary volume analysis can be performed on each property. The software also includes a time-dependent, particle-based model for the oxidation of fibrous materials. PuMA was developed for Linux operating systems and is available as a NASA software under a US & Foreign release.

Model for Analysis of Energy Demand (MAED-2)

International Nuclear Information System (INIS)

2007-01-01

The IAEA has been supporting its Member States in the area of energy planning for sustainable development. Development and dissemination of appropriate methodologies and their computer codes are important parts of this support. This manual has been produced to facilitate the use of the MAED model: Model for Analysis of Energy Demand. The methodology of the MAED model was originally developed by. B. Chateau and B. Lapillonne of the Institute Economique et Juridique de l'Energie (IEJE) of the University of Grenoble, France, and was presented as the MEDEE model. Since then the MEDEE model has been developed and adopted to be appropriate for modelling of various energy demand system. The IAEA adopted MEDEE-2 model and incorporated important modifications to make it more suitable for application in the developing countries, and it was named as the MAED model. The first version of the MAED model was designed for the DOS based system, which was later on converted for the Windows system. This manual presents the latest version of the MAED model. The most prominent feature of this version is its flexibility for representing structure of energy consumption. The model now allows country-specific representations of energy consumption patterns using the MAED methodology. The user can now disaggregate energy consumption according to the needs and/or data availability in her/his country. As such, MAED has now become a powerful tool for modelling widely diverse energy consumption patterns. This manual presents the model in details and provides guidelines for its application

Evaluation of the alcoholic fermentation of aqueous extract of the apple pomace/ Avaliação da fermentação alcoólica do extrato de bagaço de maçã

Directory of Open Access Journals (Sweden)

Gilvan Wosiacki

2005-06-01

Full Text Available The main by-product of apple agroindustry, the apple pomace, may represent from 20 to 40% of the total amount of processed raw material. Indeed, this apple pomace has been used for animal breeding or simply delivered on the soil. However, due to its composition it may cause diarrhea in cattle and also show a high environmental impact. This work was designed to evaluate such a rejected industrial residue concerning the quality of the aqueous extract for alcoholic fermented production. The variety Fuji was processed in a laboratory scale and its apple juice was a reference. The apple pomace was divided in three parts with the same weight. The first one was treated with water 1/1 (v/m, homogenized and pressed; this extract was added to the second part and homogenized and pressed. This second extract was added to the last part, and also homogenized and pressed. The composition of the apple juice and of the extract were determined before and after the fermentation. The extract showed 60% as yield of the total sugars and total acidity were the same in the apple juice. The total nitrogen and N a-amino acid concentration were both higher in the extract as compared to the apple juice. The yeast did not present any lack for the fermentation process. Apple pomace extract was suitable substrate for alcohol fermentative process. The apple juice, extract pomace and extract pomace added with sacarose fermentation show 6,9ºGL, 4,30ºGL e 7,30ºGL, respectively.O principal subproduto da agroindústria da maçã, o bagaço, pode representar de 20 a 40% da quantidade total de maçã processada. Atualmente está sendo utilizado na alimentação animal ou simplesmente dispensado no solo como adubo orgânico. Entretanto, devido à sua constituição pode causar hiper-alcoolemia no gado e também acarretar problemas ambientais. Neste trabalho foi avaliado o aproveitamento do bagaço de maçã do cultivar Fuji para a obtenção de extrato aquoso para a fermenta

Extent of chromium contamination beneath the 60s pits in the Chemical Waste Landfill at Sandia National Laboratories, Albuquerque, New Mexico

International Nuclear Information System (INIS)

Johnson, R.

1994-09-01

Plume trademark and SitePlanner trademark were used to analyze the extent of chromium contamination beneath the 60s pits in the Chemical Waste Landfill at Sandia National Laboratories. On the basis of Plume trademark's analysis with currently available sampling and the proper locations for that sampling. Finally, a retrospective study was conducted for the site that evaluated the potential for cost savings if the characterization effort had followed an adaptive sampling program approach. Included in this retrospective study was an analysis of the impacts that spatial autocorrelation, soft information, and alternative sampling program goals have on sampling program progress. The conclusion is that by relying on an adaptive sampling program approach at the 60s pits, and leveraging the little soft information that is available for this location, a significant gain in information could have been realized for the same number of bores

Cinéma en France

Directory of Open Access Journals (Sweden)

Michel VIGOUROUX

1992-06-01

Full Text Available Le cinéma est l’objet de bases de données exhaustives sur les équipements et les fréquentations. Les données sur les salles permettent d’identifier le phénomène de concentration de propriété et d’exploitation. La perspective dynamique peut être observée sur 45 ans. À l’échelle régionale, on peut apprécier le dynamisme du cinéma en haute montagne alpine et la différence de réseaux sur le territoire (France de l’Ouest.

Echt und modern? Diskurse über Männlichkeit

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Florian Kahofer

2014-09-01

Full Text Available Der vorliegende Artikel befasst sich mit Repräsentationen von Männlichkeit im österreichischen Lifestyle-Magazin für Männer Wiener. Durch eine korpusbasierte Diskursanalyse wird ein umfassendes Korpus aller Ausgaben des Wieners von Anfang 2002 bis Ende 2012 untersucht. Auf theoretischer Ebene wird dabei eine Verbindung von Kritischer Männlichkeitsforschung (KMF und Feministisch Kritischer Diskursanalyse (FCDA unternommen. Es werden aktuelle Veröffentlichungen zu Kritischer Diskursanalyse und Männlichkeit vorgestellt und diskutiert. Durch den Einsatz einer Konkordanzsoftware werden Konkordanzen des Nomens MANN analysiert. Diese werden allerdings insofern eingeschränkt betrachtet, als nur Nominationen in der Form der häufigsten Adjektiv-Konstruktionen untersucht werden. Die Ergebnisse zeigen, dass neben den Diskursen über Krise und Neue Männlichkeit Themen wie Alter, Körper oder Beziehung auftauchen. Männlichkeit wird als ambivalent und vielfältig dargestellt. Deutungskämpfe um Männlichkeit lassen sich ausmachen.

Treatment of anti-Ma2/Ta paraneoplastic syndrome.

Science.gov (United States)

Kraker, Jessica

2009-01-01

The paraneoplastic syndrome caused by Ma2/Ta antibodies alone (not in conjunction with Ma1 or Ma3 antibodies) varies in presentation from classic limbic encephalitis. The Ma2 syndrome may present with symptoms referable to the brainstem, diencephalon, and limbic system. These clinical symptoms are accompanied by MRI changes and abnormal electroencephalographic findings. It is important to recognize when the encephalitic syndrome is secondary to Ma2 paraneoplastic antibodies, as the patients improve or stabilize most often when the underlying carcinoma is treated. Treatment of the paraneoplastic syndrome begins with recognition of the symptoms, such as memory impairment, seizures, sleep disturbances, bradykinesia or hypokinesia, and eye movement abnormalities. If a primary tumor is discovered during the workup, it should be removed and treated with the most up-to-date oncologic treatment available. In addition to oncologic treatment, the syndrome may be treated with an immunosuppressant regimen to optimize the neurologic outcome. Leaving the patient untreated will result in decline and eventual death from the cancer itself or from complications of the paraneoplastic syndrome.

Radiation loss and global energy balance of ohmically heated divertor discharge in JT-60 tokamak

International Nuclear Information System (INIS)

Koide, Yoshihiko; Yamada, Kimio; Yoshida, Hidetoshi; Nakamura, Hiroo; Niikura, Setsuo; Tsuji, Shunji

1986-03-01

Divertor experiment in JT-60 with a small divertor chamber has been successfully performed up to 1.6 MA discharge. Several divertor effects were experimentally confirmed as follows. Radiation loss in main plasma saturates with the increase of plasma current and its ratio to the input power is about 20 % at 1.5 MA. The rest of input power is exhausted into the divertor chamber and a half of it is dissipated as the radiation loss. Impurity accumulation is not observed during a few sec without internal MHD activity and gross impurity confinement time is several hundred msec. (author)

Compter mes jours : recherche explorant l'espace entre ma pratique artistique et ma pratique comptable

OpenAIRE

Picard, Julie

2017-01-01

Cette recherche propose d’investiguer l’espace entre ma pratique artistique et ma pratique comptable à travers une approche qui déploie des activités de recherches théoriques sur l’art, des activités de recherches théoriques en comptabilité, la réalisation d’un protocole de création en atelier, et la prestation d’une conférence. L’approche flexible, multifocale et exploratoire adoptée se situe en affinité avec Intermedia, développé par Dick Higgins. Partant de ces deux figures type d’oppositi...

Reconciling Conflicting Geologic and Thermochronologic Interpretations Via Multiple Apatite Thermochronometers (AHe, AFT, and 4He/3He): 6 Ma Incision of the Westernmost Grand Canyon

Science.gov (United States)

Winn, C.; Karlstrom, K. E.; Shuster, D. L.; Kelley, S.; Fox, M.

2017-12-01

The application of low-temperature apatite thermochronology to the incision history of the Grand Canyon has led to conflicting hypotheses of either a 70 Ma ("old") or conflict with these lines of evidence and indicate a much older ( 70 Ma) westernmost Grand Canyon. We reconcile this conflict by applying apatite (U-Th)/He ages (AHe), 4He/3He thermochronometry, and apatite fission track ages and lengths (AFT) to the same sample at a key location. Using HeFTy, t-T paths that predict these data show cooling from ˜100 °C to 40-60 °C at 70-50 Ma, long-term residence at 40-60 °C from 50-10 Ma, and cooling to surface temperatures after 10 Ma, indicating young incision. New AFT (5) and AHe (3) datasets are also presented here. When datasets are examined separately, AHe data show t-T paths that cool to surface temperatures during the Laramide, consistent with an "old" Canyon. When multiple methods are applied, t-T paths instead show young incision. This inconsistency demonstrates the age of the Grand Canyon controversy. Here we reconcile the difference in t-T paths by adjusting model parameters to account for uncertainty in the rate of radiation damage annealing in apatite during burial heating and the resulting variations in He retentivity. In this area, peak burial conditions during the Laramide were likely insufficient to fully anneal radiation damage that accumulated during prolonged near-surface residence prior to burial. We conclude that application of multiple thermochronometers from common rocks reconciles conflicting thermochronologic interpretations and these data are best explained by a "young" westernmost Grand Canyon.

REGENERASI DAN PERBANYAKAN RUMPUT LAUT Kappaphycus alvarezii HASIL TRANSFORMASI GEN SUPEROKSIDA DISMUTASE (MaSOD

Directory of Open Access Journals (Sweden)

Emma Suryati

2017-01-01

culture flask. Regeneration and multiplication of those seaweed were conducted in a laboratory flask cultures placed in a “culture chamber” which was aerated and enriched with fertilizers PES, Grund, Conwy, and SSW as a control, salinity 20, 25, 30, 35, and 40 g/L, pH: 4, 5, 6, 7, and 8. the light intensity between 500-2000 lux, with light and dark photoperiod 8:16; 12:12; and 16:8. To stimulate the growth of explants the addition of growth hormone IAA and BAP with ratios of 1:1, 1:2 and 2:1 were performed. This study was a multiple-step of process, by which transgenic explants was identified by PCR method. The results showed that the highest survival rate was obtained using media PES (94%, salinity 30 g / L (90%, pH= 7 (96%, the intensity of light at 1500 lux (80%, photoperiod= 12: 12 (84%, and ratio of IAA and BAP 2: 1. The results of PCR analysis showed the putative K. alvarezii transgenic MaSOD was 78% of explants.

Synthesis of 9,9,9-trideutero-1,4-dihydroxynonane mercapturic acid (d3-DHN-MA), a useful internal standard for DHN-MA urinalysis.

Science.gov (United States)

Chantegrel, B; Deshayes, C; Doutheau, A; Steghens, J P

2002-10-01

Racemic 1,4-dihydroxynonane mercapturic acid (DHN-MA) and 9,9,9-trideutero-1,4-dihydroxynonane mercapturic acid (d3-DHN-MA) are synthesized on a 400-mg scale (overall yield approximately 40%) by a two-step sequence involving Michael addition of N-acetyl-L-cysteine to methyl 4-hydroxynon-2(E)-enoate or methyl 9,9,9-trideutero-4-hydroxynon-2 (E)-enoate, followed by reduction of the intermediate adducts with lithium borohydride. The requisite starting methyl esters are obtained, respectively, from heptanal or 7,7,7-trideuteroheptanal and methyl 4-chlorophenylsulfinylacetate via a sulfoxide piperidine and carbonyl reaction described in the literature. The 7,7,7-trideuteroheptanal is easily prepared by classical methods in four steps from 6-bromo-1-hexanol. 13C NMR data indicate that DHN-MA as well as d3-DHN-MA are obtained as mixtures of four diastereomers. Preliminary results show that d3-DHN-MA could be used as an internal standard for mass spectrometric quantification of DHN-MA in human urine.

MA-burners efficiency parameters allowing for the duration of transmutation process

International Nuclear Information System (INIS)

Gulevich, A.; Zemskov, E.; Kalugin, A.; Ponomarev, L.; Seliverstov, V.; Seregin, M.

2010-01-01

Transmutation of minor actinides (MA) means their transforming into the fission products. Usually, MA-burner's transmutation efficiency is characterized by the static parameters only, such as the number of neutrons absorbed and the rate of MA feeding. However, the proper characterization of MA-burner's efficiency additionally requires the consideration of parameters allowing for the duration of the MA transmutation process. Two parameters of that kind are proposed: a) transmutation time τ - mean time period from the moment a mass of MA is loaded into the burner's fuel cycle to be transmuted to the moment this mass is completely transmuted; b) number of reprocessing cycles n rep - effective number of reprocessing cycles a mass of loaded MA has to undergo before being completely transmuted. Some of MA-burners' types have been analyzed from the point of view of these parameters. It turned out that all of them have the value of parameters too high from the practical point of view. It appears that some new approaches to MA-burner's design have to be used to significantly reduce the value of these parameters in order to make the large-scale MA transmutation process practically reasonable. Some of such approaches are proposed and their potential efficiency is discussed. (authors)

Heating experiments of JT-60

International Nuclear Information System (INIS)

1987-01-01

In JT-60, after the finish of the first stage Joule experiment, the heating facilities were installed, and the heating experiment was started in August, 1986. As to neutral beam injection, the beam injection experiment at the maximum rating 20 MW carried out, and also as to RF, the injection experiment up to 1.4 MW was carried out in both ion cyclotron and low band hybrid waves. The results worthy of special mention in the heating experiment were the success in the current drive up to 1.7 MA at maximum using low band hybrid waves and the improvement of plasma confinement characteristics obtained by the compound heating of NBI and RF. In this paper, the main results of these heating experiments and their significance are explained. The JT-60 is the testing facilities for attaining the critical plasma condition by additionally heating the plasma which is generated by Joule electric discharge with NBI and RF heatings. The experimental operation cycle of the JT-60 consists of the unit cycle of two weeks, and the number of days in operation is nine days. The temperature of heated plasma rose to 70 million deg C in the 20 MW NBI heating. Hereafter, the improvement of confinement time by increasing the stored energy of plasma is attempted. (Kako, I.)

One-year outcomes of AquaLase cataract surgery.

Science.gov (United States)

Yoo, Sonia H; Bhatt, Anand B

2007-01-01

The authors report surgical experience and clinical outcomes up to 1 year postoperatively in patients who underwent cataract surgery with the AquaLase liquefaction device (Alcon Laboratories, Fort Worth, TX). The device is a handpiece option for use with Alcon's Infiniti Vision System that uses heated balanced saline solution micropulses to liquefy lenticular material. Twenty-seven eyes of 23 patients underwent cataract extraction with the use of the AquaLase liquefaction device. The average age of participants was 68 years, and the average nuclear sclerotic grade was 1.96 on a 4-point scale. Outcomes were judged by metrics such as visual acuity, inflammation, endothelial cell count, and postoperative posterior capsule opacification. At 30 days postoperatively, 78% of eyes had a best-corrected visual acuity of 20/20. Visual acuity was 20/25 or better 1 year postoperatively in 88% of patients without complications except conversion to ultrasound phacoemulsification for two dense cataracts.

Synthesis, Biodistribution and In vitro Evaluation of Brain Permeable High Affinity Type 2 Cannabinoid Receptor Agonists [11C]MA2 and [18F]MA3.

Science.gov (United States)

Ahamed, Muneer; van Veghel, Daisy; Ullmer, Christoph; Van Laere, Koen; Verbruggen, Alfons; Bormans, Guy M

2016-01-01

The type 2 cannabinoid receptor (CB2) is a member of the endocannabinoid system and is known for its important role in (neuro)inflammation. A PET-imaging agent that allows in vivo visualization of CB2 expression may thus allow quantification of neuroinflammation. In this paper, we report the synthesis, radiosynthesis, biodistribution and in vitro evaluation of a carbon-11 ([ 11 C]MA2) and a fluorine-18 ([ 18 F]MA3) labeled analog of a highly potent N -arylamide oxadiazole CB2 agonist (EC 50 = 0.015 nM). MA2 and MA3 behaved as potent CB2 agonist (EC 50 : 3 nM and 0.1 nM, respectively) and their in vitro binding affinity for h CB2 was found to be 87 nM and 0.8 nM, respectively. Also MA3 (substituted with a fluoro ethyl group) was found to have higher binding affinity and EC 50 values when compared to the originally reported trifluoromethyl analog 12 . [ 11 C]MA2 and [ 18 F]MA3 were successfully synthesized with good radiochemical yield, high radiochemical purity and high specific activity. In mice, both tracers were efficiently cleared from blood and all major organs by the hepatobiliary pathway and importantly these compounds showed high brain uptake. In conclusion, [ 11 C]MA2 and [ 18 F]MA3 are shown to be high potent CB2 agonists with good brain uptake, these favorable characteristics makes them potential PET probes for in vivo imaging of brain CB2 receptors. However, in view of its higher affinity and selectivity, further detailed evaluation of MA3 as a PET tracer for CB2 is warranted.

Synthesis and thermal properties of the MA/HDPE composites with nano-additives as form-stable PCM with improved thermal conductivity

International Nuclear Information System (INIS)

Tang, Yaojie; Su, Di; Huang, Xiang; Alva, Guruprasad; Liu, Lingkun; Fang, Guiyin

2016-01-01

Highlights: • MA/HDPE composites with nano-additives were prepared for thermal conductivity enhancement. • Microstructure and chemical structure of the FSPCM were analyzed. • Thermal properties and thermal reliability of the FSPCM were investigated. • Thermal conductivity of the FSPCM can be enhanced by adding NAO and NG. - Abstract: For the purpose of improving the thermal conductivity of the form–stable phase change materials (FSPCM), two types of nano–powders with high thermal conductivity were added into the samples. In the modified FSPCM, myristic acid (MA) was used as a solid–liquid phase change material (PCM), high density polyethylene (HDPE) acted as supporting material to prevent the leakage of the melted MA. Nano–Al 2 O 3 (NAO) and nano–graphite (NG) were the additives for thermal conductivity enhancement. Scanning electronic microscope (SEM), Fourier transformation infrared spectroscope (FT–IR) and X-ray diffractometer (XRD) were used to analyze the microstructure, chemical structure and crystalline phase of the samples, respectively. Furthermore, the specific latent heat and phase transition temperature, thermal conductivity and thermal reliability were investigated using differential scanning calorimeter (DSC), thermal conductivity meter and thermo–gravimetric analyzer (TGA). The results showed that the MA was uniformly absorbed in the HDPE matrices and there was no leakage during the melting process when the mass fraction of the MA in the MA/HDPE composite was less than 70%. The DSC results revealed that the modified FSPCM have a constant phase change temperature and high specific latent heat. The thermal conductivity of the FSPCM was measured in the solid (30 °C) and liquid (60 °C) states of the MA. When the mass fraction of nano–powder additives is 12%, the thermal conductivities of the FSPCM increase by 95% (NAO) and 121% (NG) at 30 °C. It is anticipated that the FSPCM possess a potential application for thermal energy

Acoustic Split-Beam Echosounder Data (EK60)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Southeast Fisheries Science Center Mississippi Laboratories collects data using Simrad EK60 scientific split-beam acoustic echosounders during resource...

MA-burners efficiency parameters allowing for the duration of transmutation process

Energy Technology Data Exchange (ETDEWEB)

Gulevich, A.; Zemskov, E. [Institute of Physics and Power Engineering, Bondarenko Square 1, Obninsk, Kaluga Region 249020 (Russian Federation); Kalugin, A.; Ponomarev, L. [Russian Research Center ' ' Kurchatov Institute' ' Kurchatov Square 1, Moscow 123182 (Russian Federation); Seliverstov, V. [Institute of Theoretical and Experimental Physics ul.B. Cheremushkinskaya 25, Moscow 117259 (Russian Federation); Seregin, M. [Russian Research Institute of Chemical Technology Kashirskoe Shosse 33, Moscow 115230 (Russian Federation)

2010-07-01

Transmutation of minor actinides (MA) means their transforming into the fission products. Usually, MA-burner's transmutation efficiency is characterized by the static parameters only, such as the number of neutrons absorbed and the rate of MA feeding. However, the proper characterization of MA-burner's efficiency additionally requires the consideration of parameters allowing for the duration of the MA transmutation process. Two parameters of that kind are proposed: a) transmutation time {tau} - mean time period from the moment a mass of MA is loaded into the burner's fuel cycle to be transmuted to the moment this mass is completely transmuted; b) number of reprocessing cycles n{sub rep} - effective number of reprocessing cycles a mass of loaded MA has to undergo before being completely transmuted. Some of MA-burners' types have been analyzed from the point of view of these parameters. It turned out that all of them have the value of parameters too high from the practical point of view. It appears that some new approaches to MA-burner's design have to be used to significantly reduce the value of these parameters in order to make the large-scale MA transmutation process practically reasonable. Some of such approaches are proposed and their potential efficiency is discussed. (authors)

Synthesis, biodistribution and in vitro evaluation of brain permeable high affinity type 2 cannabinoid receptor agonists [11C]MA2 and [18F]MA3

Directory of Open Access Journals (Sweden)

Muneer Ahamed

2016-09-01

Full Text Available Abstract The type 2 cannabinoid receptor (CB2 is a member of the endocannabinoid system and is known for its important role in (neuroinflammation. A PET-imaging agent that allows in vivo visualization of CB2 expression may thus allow quantification of neuroinflammation. In this paper, we report the synthesis, radiosynthesis, biodistribution and in vitro evaluation of a carbon-11 ([11C]MA2 and a fluorine-18 ([18F]MA3 labeled analogue of a highly potent N-arylamide oxadiazole CB2 agonist (EC50 = 0.015 nM. MA2 and MA3 behaved as potent CB2 agonist (EC50: 3 nM and 0.1 nM, respectively and their in vitro binding affinity for hCB2 was found to be 87 nM and 0.8 nM, respectively. Also MA3 (substituted with a fluoro ethyl group was found to have higher binding affinity and EC50 values when compared to the originally reported trifluoromethyl analogue 12. [11C]MA2 and [18F]MA3 were successfully synthesized with good radiochemical yield, high radiochemical purity and high specific activity. In mice, both tracers were efficiently cleared from blood and all major organs by the hepatobiliary pathway and importantly these compounds showed high brain uptake. In conclusion, [11C]MA2 and [18F]MA3 are shown to be high potent CB2 agonists with good brain uptake, these favorable characteristics makes them potential PET probes for in vivo imaging of brain CB2 receptors. However in view of its higher affinity and selectivity, further detailed evaluation of MA3 as a PET tracer for CB2 is warranted.

The HectoMAP Cluster Survey. I. redMaPPer Clusters

Science.gov (United States)

Sohn, Jubee; Geller, Margaret J.; Rines, Kenneth J.; Hwang, Ho Seong; Utsumi, Yousuke; Diaferio, Antonaldo

2018-04-01

We use the dense HectoMAP redshift survey to explore the properties of 104 redMaPPer cluster candidates. The redMaPPer systems in HectoMAP cover the full range of richness and redshift (0.08 systems included in the Subaru/Hyper Suprime-Cam public data release are bona fide clusters. The median number of spectroscopic members per cluster is ∼20. We include redshifts of 3547 member candidates listed in the redMaPPer catalog whether they are cluster members or not. We evaluate the redMaPPer membership probability spectroscopically. The purity (number of real systems) in redMaPPer exceeds 90% even at the lowest richness. Three massive galaxy clusters (M ∼ 2 × 1013 M ⊙) associated with X-ray emission in the HectoMAP region are not included in the public redMaPPer catalog with λ rich > 20, because they lie outside the cuts for this catalog.

Valor Comparativo entre la Yuca y el Maíz en la Alimentación de Cerdos

Directory of Open Access Journals (Sweden)

Rodolfo Mejía Tomás

1960-12-01

Full Text Available 1-Se utilizaron 3 grupos de 7 cerdos cada uno en ensayos comparativos entre la yuca y el maíz. La yuca formó el 40% de la ración N° 1; la ración N° 2 tuvo 20% de yuca y 20% de maíz, y la N° 3, 40% de maíz. El 60% restante en todas las raciones estuvo constituido por harina de maíz (20%, salvado de trigo (9%, torta de ajonjolí (15 %, harina de pescado (5 %, torta de algodón (10% y minersal (1 %. A cada tonelada de alimento se le adicionó 1 libra de Aurofac. El experimento fue llevado a cabo en las porquerizas de la Facultad Nacional de Agronomía, localizadas en el Valle de Medellín (1.540 metros sobre el nivel del mar y 21 °C. de temperatura media. 2-Los cerdos se pesaron con intervalos de 14 días. a una misma hora y antes de que recibieron alimento. 3 -La ración N° 1 (con 40% de yuca superó a la ración N° 2 (20% de yuca y 20% de maíz y a la N° 3 (con 40% de maíz en el levante y engorde de cerdos. 4 -La ganancia diaria fue muy variable durante todo el experimento, pero al final fueron (en promedio de 0.607 kilos en el lote N°1, 0.544 en el N° 2 y 0.527 en el tercero, que correspondían a las raciones 1, 2 y 3 respectivamente. 5 -El consumo de alimento fue más o menos igual en todos los lotes. 6 -Los cerdos alimentados con la ración N°1 tuvieron una eficiencia de 4.63: 1; los de los números 2 y 3 de 5.19: 1 y 5.29: 1 respectivamente.

Medical therapy cost considerations for glaucoma.

Science.gov (United States)

Fiscella, Richard G; Green, Amy; Patuszynski, Daniel H; Wilensky, Jacob

2003-07-01

To determine the calculated daily patient cost (cost minimization) of medical glaucoma therapy and review cost trends. Experimental, controlled, prospective study. The actual volume of various glaucoma medications or glaucoma medications with redesigned bottles was determined for most commercially available sizes of the tested products. The drops per milliliter based on the actual volume and the daily costs of the dosage schedules recommended by the manufacturers were compared. The cost of each bottle of medication was determined from the average wholesale price (AWP) in the United States. A comparison to 1999 prices where applicable will be analyzed to review costing trends. The generic timolol products (range, US dollars 0.38-US dollars 0.46 per day) were similar on a cost per day basis vs Betimol (Santen, Napa Valley, California, USA), Optipranolol (Bausch and Lomb Pharmaceuticals, Tampa, Florida, USA) and Timoptic (Merck, West Point, Pennsylvania, USA). Their percentage cost increase ranged from 5% to 22% since 1999, except for generic timolol XE gel-forming solution (48%). Betagan (Allergan, Irvine, California, USA), Betoptic S (Alcon Laboratories, Fort Worth, Texas, USA), and Ocupress (Novartis, Duluth, Georgia, USA) ranged from US dollars 0.88 to US dollars 1.11 per day, and their percentage cost increase ranged from 33% to 53%. Some brand-only products have raised their AWPs a greater percentage, including Betoptic S (37%), Iopidine (Alcon, Fort Worth, Texas, USA) (50%), Ocupress (Novartis Ophthalmics, Duluth, Georgia, USA) (53%), and Pilopine gel (Alcon, Fort Worth, Texas, USA) (32%). The mean cost per day for the topical carbonic anhydrase inhibitors Azopt (Alcon Laboratories; US dollars 1.33 per day) and Trusopt (Merck; US dollars 1.05 per day) differed from 1999 when prices were almost identical. Cosopt (Merck; timolol 0.5% plus dorzolamide 2%, US dollars 1.04 per day) was less than the cost of separate bottles of a topical carbonic anhydrase inhibitor

Mass and Reliability System (MaRS)

Science.gov (United States)

Barnes, Sarah

2016-01-01

The Safety and Mission Assurance (S&MA) Directorate is responsible for mitigating risk, providing system safety, and lowering risk for space programs from ground to space. The S&MA is divided into 4 divisions: The Space Exploration Division (NC), the International Space Station Division (NE), the Safety & Test Operations Division (NS), and the Quality and Flight Equipment Division (NT). The interns, myself and Arun Aruljothi, will be working with the Risk & Reliability Analysis Branch under the NC Division's. The mission of this division is to identify, characterize, diminish, and communicate risk by implementing an efficient and effective assurance model. The team utilizes Reliability and Maintainability (R&M) and Probabilistic Risk Assessment (PRA) to ensure decisions concerning risks are informed, vehicles are safe and reliable, and program/project requirements are realistic and realized. This project pertains to the Orion mission, so it is geared toward a long duration Human Space Flight Program(s). For space missions, payload is a critical concept; balancing what hardware can be replaced by components verse by Orbital Replacement Units (ORU) or subassemblies is key. For this effort a database was created that combines mass and reliability data, called Mass and Reliability System or MaRS. The U.S. International Space Station (ISS) components are used as reference parts in the MaRS database. Using ISS components as a platform is beneficial because of the historical context and the environment similarities to a space flight mission. MaRS uses a combination of systems: International Space Station PART for failure data, Vehicle Master Database (VMDB) for ORU & components, Maintenance & Analysis Data Set (MADS) for operation hours and other pertinent data, & Hardware History Retrieval System (HHRS) for unit weights. MaRS is populated using a Visual Basic Application. Once populated, the excel spreadsheet is comprised of information on ISS components including

Intelligent Acquisition System Used in Mechanical Laboratory

Directory of Open Access Journals (Sweden)

Rob Raluca

2016-01-01

Full Text Available The main purpose of this paper consists in determining of the parameters which characterize the functioning of the Teves MK 60 as an ABS-ESP braking laboratory stand. This braking system model is used by the Volkswagen Golf and Bora the since 2002. The braking laboratory stand is able to simulate many operations which are able to give information concerning the ABS-ESP braking system comparing to the classical braking system. An application designed in LabVIEW comes to acquire and to process in real time the electrical signals generated by the Teves MK 60 laboratory stand.

Sandia National Laboratories:

Science.gov (United States)

Environmental Management System Pollution Prevention History 60 impacts Diversity Locations Facts & Figures Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers

Millennium Ecosystem Assessment: MA Ecosystems

Data.gov (United States)

National Aeronautics and Space Administration — The Millennium Ecosystem Assessment: MA Ecosystems provides data and information on the extent and classification of ecosystems circa 2000, including coastal,...

Millennium Ecosystem Assessment: MA Biodiversity

Data.gov (United States)

National Aeronautics and Space Administration — The Millennium Ecosystem Assessment: MA Biodiversity provides data and information on amphibians, disease agents (extent and distribution of infectious and parasitic...

Target Plate Material Influence on Fullerene-C60 Laser Desorption/Ionization Efficiency

Science.gov (United States)

Zeegers, Guido P.; Günthardt, Barbara F.; Zenobi, Renato

2016-04-01

Systematic laser desorption/ionization (LDI) experiments of fullerene-C60 on a wide range of target plate materials were conducted to gain insight into the initial ion formation in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. The positive and negative ion signal intensities of precursor, fragment, and cluster ions were monitored, varying both the laser fluence (0-3.53 Jcm-2) and the ion extraction delay time (0-950 ns). The resulting species-specific ion signal intensities are an indication for the ionization mechanisms that contribute to LDI and the time frames in which they operate, providing insight in the (MA)LDI primary ionization. An increasing electrical resistivity of the target plate material increases the fullerene-C60 precursor and fragment anion signal intensity. Inconel 625 and Ti90/Al6/V4, both highly electrically resistive, provide the highest anion signal intensities, exceeding the cation signal intensity by a factor ~1.4 for the latter. We present a mechanism based on transient electrical field strength reduction to explain this trend. Fullerene-C60 cluster anion formation is negligible, which could be due to the high extraction potential. Cluster cations, however, are readily formed, although for high laser fluences, the preferred channel is formation of precursor and fragment cations. Ion signal intensity depends greatly on the choice of substrate material, and careful substrate selection could, therefore, allow for more sensitive (MA)LDI measurements.

46 CFR 308.545 - Facultative cargo policy, Form MA-316.

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Facultative cargo policy, Form MA-316. 308.545 Section 308.545 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK... policy, Form MA-316. The standard form of War Risk Facultative Cargo Policy, Form MA-316, may be obtained...

{sup 186}Re-maSGS-Z{sub HER2:342}, a potential affibody conjugate for systemic therapy of HER2-expressing tumours

Energy Technology Data Exchange (ETDEWEB)

Orlova, Anna; Tran, Thuy A. [Uppsala University, Division of Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala (Sweden); Ekblad, Torun; Karlstroem, Amelie Eriksson [Royal Institute of Technology, School of Biotechnology, Division of Molecular Biotechnology, Stockholm (Sweden); Tolmachev, Vladimir [Uppsala University, Division of Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala (Sweden); Uppsala University, Division of Nuclear Medicine, Department of Medical Sciences, Uppsala (Sweden)

2010-02-15

Affibody molecules are a novel class of tumour-targeting proteins, which combine small size (7 kDa) and picomolar affinities. The Affibody molecule Z{sub HER2:342} has been suggested for imaging of HER2 expression in order to select patients for trastuzumab therapy. When optimizing chelators for {sup 99m}Tc-labelling, we have found that synthetic Z{sub HER2:342} conjugated with mercaptoacetyl-glycyl-glycyl-glycyl (maGGG) and mercaptoacetyl-glycyl-seryl-glycyl (maGSG) chelators provides relatively low renal uptake of radioactivity and could be suitable for therapy. maGGG-Z{sub HER2:342} and maGSG-Z{sub HER2:342} were labelled with {sup 186}Re and their biodistribution was studied in normal mice. Dosimetric evaluation and tumour targeting to HER2-overexpressed xenografts (SKOV-3) by {sup 186}Re-maGSG-Z{sub HER2:342} were studied. Gluconate-mediated labelling of maGGG-Z{sub HER2:342} and maGSG-Z{sub HER2:342} with {sup 186}Re provided a yield of more than 95% within 60 min. The conjugates were stable and demonstrated specific binding to HER2-expressing SKOV-3 cells. Biodistribution in normal mice demonstrated rapid blood clearance, low accumulation of radioactivity in the kidney and other organs, accumulating free perrhenate. Both {sup 186}Re-maGGG-Z{sub HER2:342} and {sup 186}Re-maGSG-Z{sub HER2:342} demonstrated lower renal uptake than their {sup 99m}Tc-labelled counterparts. {sup 186}Re-maGSG-Z{sub HER2:342} provided the lowest uptake in healthy tissues. Biodistribution of {sup 186}Re-maGSG-Z{sub HER2:342} in nude mice bearing SKOV-3 xenografts showed specific targeting of tumours. Tumour uptake 24 h after injection (5.84{+-}0.54%ID/g) exceeded the concentration in blood by more than 500-fold, and uptake in kidneys by about 8-fold. Preliminary dosimetric evaluation showed that dose-to-tumour should exceed dose-to-kidney by approximately 5-fold. Optimization of chelators improves biodistribution properties of rhenium-labelled small scaffold proteins and enables

Analysis of rocks particulates by VNIR spectroscopy with Ma_Miss instrument breadboard.

Science.gov (United States)

De Angelis, Simone; Altieri, Francesca; Giardino, Marco; Ammannito, Eleonora; Carli, Cristian; Frigeri, Alessandro; De Sanctis, Maria Cristina

Ma_Miss (Mars Multispectral Imager for Subsurface Studies) miniaturized spectrometer will investigate the Martian subsurface in the Visible and Near Infrared spectral range 0.4-2.2 mum, with 120 mum spatial resolution, and 20 nm of spectral resolution. It will be integrated in the Drill of the Pasteur Rover of the ExoMars 2018 mission, and will acquire spectra of the borehole wall performed by the Drill in the subsoil, at depths down to 2 meters. The main objective of Exomars mission is the search of present or past life and the investigation about the conditions favourable to the development of life. So the characterization of the possible water geochemical environment is the primary goal: thus objectives will be the search for hydrated silicates as well as carbonate or sulphate layers. The goal of Ma_Miss is the study of the Martian subsurface, and its principal scientific objectives are: the determination of the subsurface mineralogy and the reconstraction of a stratigraphic column or sequence, by means of Visible and Near Infrared reflectance spectroscopy; the characterization of physical properties of materials. The instrument breadboard is operative at the IAPS/INAF laboratory; it consists of the main subsystems except the spectrometer, that is a commercial spectrometer (FieldSpec Pro ©): a 5 W lamp supplies the illumination; an optical fibres bundle carries the light from the lamp to the Optical Head, which has the double task of focusing the light on the observed target and of collecting the scattered light from the target. The illumination spot on the target is 1 mm in diameter, while the light is recollected from a 120-mum spot. A single optical fibre carries the collected light from the Optical Head to the spectrometer. The interface between the Optical Head and the external wall is the Sapphire Window, which has high hardness and transparency. The light is focused on the wall at a distance of less than 1 mm outside the Sapphire Window. In this work

M&A information technology best practices

CERN Document Server

Roehl-Anderson, Janice M

2013-01-01

Add value to your organization via the mergers & acquisitions IT function  As part of Deloitte Consulting, one of the largest mergers and acquisitions (M&A) consulting practice in the world, author Janice Roehl-Anderson reveals in M&A Information Technology Best Practices how companies can effectively and efficiently address the IT aspects of mergers, acquisitions, and divestitures. Filled with best practices for implementing and maintaining systems, this book helps financial and technology executives in every field to add value to their mergers, acquisitions, and/or divestitures via the IT

42 CFR 422.4 - Types of MA plans.

Science.gov (United States)

2010-10-01

... availability, service area, and quality. (ii) Coordinated care plans may include mechanisms to control... requirements of sections 138 and 220 of the Internal Revenue Code. (3) MA private fee-for-service plan. An MA... Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...

Ma(d)skulinitet

DEFF Research Database (Denmark)

Leer, Jonatan

Når tv-kokke som Jamie Oliver, Gordon Ramsay og brødrene Price toner frem på skærmen, laver de ikke kun mad. De mixer også maskulinitet. For når en mand laver mad, laver maden også manden. Det mener postdoc Jonatan Leer, der i Ma(ds)kulinitet. Kønskamp i tv-køkkenet præsenterer, hvordan og hvorfor...

HoCaMA: Home Care Hybrid Multiagent Architecture

Science.gov (United States)

Fraile, Juan A.; Bajo, Javier; Abraham, Ajith; Corchado, Juan M.

Home Care is one of the main objectives of Ambient Intelligence. Nowadays, the disabled and elderly population, which represents a significant part of our society, requires novel solutions for providing home care in an effective way. In this chapter, we present HoCaMA, a hybrid multiagent architecture that facilitates remote monitoring and care services for disabled patients at their homes. HoCaMA combines multiagent systems and Web services to facilitate the communication and integration with multiple health care systems. In addition, HoCaMA focuses on the design of reactive agents capable of interacting with different sensors present in the environment, and incorporates a system of alerts through SMS and MMS mobile technologies. Finally, it uses Radio Frequency IDentification and JavaCard technologies to provide advanced location and identification systems, as well as automatic access control facilities. HoCaMA has been implemented in a real environment and the results obtained are presented within this chapter.

Millennium Ecosystem Assessment: MA Population

Data.gov (United States)

National Aeronautics and Space Administration — The Millennium Ecosystem Assessment: MA Population data sets provide baseline population information as one of the drivers of ecosystem change. The data helped in...

Microcap M&A: An Exploratory Study

Directory of Open Access Journals (Sweden)

Keith Turpie

2014-06-01

Full Text Available A substantial body of accounting and finance literature has been devoted to the study of Mergers and Acquisitions (M&As dominated by discussions relating to the gains and losses that accrue from transactions involving large public companies. This paper makes a unique contribution to the literature by investigating the M&A experience of microcap businesses. Transactions involving microcap M&A are substantially different to those involving large companies on a number of dimensions. This paper explores the determinants of microcap M&A success and pitfalls and problems from an integration perspective. Due to the paucity of research in the area an exploratory research design is employed, conducting interviews with five CEOs of companies that had each managed multiple transactions. We find microcap M&As are successful when measured against identified goals but generally take longer and cost more than expected. Further, culture and communication are key issues in determining success/failure. We also find the in-house management of integration aspects is problematic for these businesses and suggest this warrants further study.

46 CFR 308.517 - Open Cargo Policy, Form MA-300.

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Open Cargo Policy, Form MA-300. 308.517 Section 308.517... Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.517 Open Cargo Policy, Form MA-300. The standard form of War Risk Open Cargo, Form MA-300, may be obtained from the American War Risk...

Changing the S and MA [Safety and Mission Assurance] Paradigm

Science.gov (United States)

Malone, Roy W., Jr.

2010-01-01

Objectives: 1) Optimize S&MA organization to best facilitate Shuttle transition in 2010, successfully support Ares developmental responsibilities, and minimize the impacts of the gap between last Shuttle flight and start of Ares V Project. 2) Improve leveraging of critical skills and experience between Shuttle and Ares. 3) Split technical and supervisory functions to facilitate technical penetration. 4) Create Chief Safety and Mission Assurance Officer (CSO) stand-alone position for successfully implementation of S&MA Technical Authority. 5) Minimize disruption to customers. 6) Provide early involvement of S&MA leadership team and frequent/open communications with S&MA team members and steak-holders.

Ability of Bottle Cap Color to Facilitate Accurate Patient-Physician Communication Regarding Medication Identity in Patients with Glaucoma.

Science.gov (United States)

Dave, Pujan; Villarreal, Guadalupe; Friedman, David S; Kahook, Malik Y; Ramulu, Pradeep Y

2015-12-01

To determine the accuracy of patient-physician communication regarding topical ophthalmic medication use based on bottle cap color, particularly among individuals who may have acquired color vision deficiency from glaucoma. Cross-sectional, clinical study. Patients aged ≥18 years with primary open-angle, primary angle-closure, pseudoexfoliation, or pigment dispersion glaucoma, bilateral visual acuity of ≥20/400, and no concurrent conditions that may affect color vision. A total of 100 patients provided color descriptions of 11 distinct medication bottle caps. Color descriptors were then presented to 3 physicians. Physicians matched each color descriptor to the medication they thought the descriptor was describing. Frequency of patient-physician agreement, occurring when all 3 physicians accurately matched the color descriptor to the correct medication. Multivariate regression models evaluated whether patient-physician agreement decreased with degree of better-eye visual field (VF) damage, color descriptor heterogeneity, or color vision deficiency, as determined by the Hardy-Rand-Rittler (HRR) score and Lanthony D15 color confusion index (D15 CCI). Subjects had a mean age of 69 (±11) years, with VF mean deviation of -4.7 (±6.0) and -10.9 (±8.4) decibels (dB) in the better- and worse-seeing eyes, respectively. Patients produced 102 unique color descriptors to describe the colors of the 11 bottle caps. Among individual patients, the mean number of medications demonstrating agreement was 6.1/11 (55.5%). Agreement was less than 15% for 4 medications (prednisolone acetate [generic], betaxolol HCl [Betoptic; Alcon Laboratories Inc., Fort Worth, TX], brinzolamide/brimonidine [Simbrinza; Alcon Laboratories Inc.], and latanoprost [Xalatan; Pfizer, Inc., New York, NY]). Lower HRR scores and higher D15 CCI (both indicating worse color vision) were associated with greater VF damage (P communication using bottle cap color alone may be common and could lead to confusion

FİLMLERLE İLETİŞİM VE YABANCILAŞMA

OpenAIRE

ÖZTÜRK, Serdar

2018-01-01

Yabancılaşma konusu genellikle iktisadi, sosyolojik ve psikoloji boyutlarıyla tartışılmıştır. Oysa bir anlam paylaşımı olarak iletişim, yabancılaşmayla doğrudan ilişkilidir. Buna karşın iletişim ile yabancılaşma ilişkisini, analize filmleri de katarak inceleyen çok az çalışma bulunmaktadır. Bu çalışma, yabancılaşma kavramını tartışarak, yabancılaşmanın iletişim ile ilişkisini incelemektedir. Buna göre insanın kendi ürettiği sembollerine, medyanın üretim bölgesinde üretilen sembollere yabancıl...

Differences of Longitudinal Chromatic Aberration (LCA) between Eyes with Intraocular Lenses from Different Manufacturers

Science.gov (United States)

Nakajima, Masashi; Hiraoka, Takahiro; Yamamoto, Toshiya; Takagi, Seiu; Hirohara, Yoko; Oshika, Tetsuro

2016-01-01

Several researchers have studied the longitudinal chromatic aberration (LCA) of eyes implanted with an intraocular lens (IOL). We investigated the LCA of eyes implanted with yellow-colored IOLs from three different manufacturers: Alcon Inc., HOYA Corp., and AMO Inc. The number of subjects was 11, 16, and 16, respectively. The LCA of eyes implanted with SN60WF and SN60AT (Alcon Inc.), and with XY-1 (HOYA Corp.), was the same as that of phakic eyes. The LCA of eyes with ZCB00V (AMO Inc.) was smaller than that of phakic eyes. The LCA of eyes implanted with Alcon’s and HOYA’s IOLs, but not the LCA of eyes implanted with AMO’s IOLs, was positively correlated with the powers of the IOLs. We also performed simulations to verify the impacts of LCA on visual performance for 4-mm pupil diameter; the simulations were a polychromatic modulation transfer function (MTF) and a visual Strehl ratio computed on the basis of an optical transfer function (VSOTF). We concluded that the differences between the LCA of different manufacturers do not affect visual performances when some extent of higher-order aberration (HOA) exists. The smaller HOA of AMO IOLs may enhance visual performance. PMID:27258141

Susceptibilidad y resistencia del maíz al hongo comestible huitlacoche (Ustilago maydis Cda. mejorando su virulencia

Directory of Open Access Journals (Sweden)

L. Martínez

2000-01-01

Full Text Available El huitlacoche es un patógeno del maíz, muy apreciado como alimento humano en la región central de México. Actualmente seis industrias lo comercializan enlatado. El total de la producción industrial se abastece de la recolección espontánea del hongo en campos de cultivo de maíz para producción de grano. Debido a lo anterior, los objetivos planteados en este estudio fueron: evaluar y seleccionar patotipos de Ustilago maydis con una alta virulencia sobre maíz; evaluar y seleccionar familias de medios hermanos maternos de maíz de reacción susceptible y resistente al huitlacoche. En 1997, se evaluaron 100 aislamientos del hongo en un híbrido experimental, seleccionando 12 de ellos por su vigor, presentando en promedio 190 g del hongo por planta infectada, y 135.24 g por planta inoculada (8.11 t×ha-1, 60 000 plantas×ha-1, índice de severidad de 36.82 y una incidencia de 70.64%. De las 300 familias de medios hermanos maternos evaluadas (1998 por inoculación con la mezcla de los 12 aislamientos seleccionados (1997, se eligieron 16 familias susceptibles, que presentaron en promedio 154.97 g del hongo por planta infectada y 112.88 g por planta inoculada (6.67 t×ha-1, 76.67 % de incidencia y 34.82 de índice de severidad; así como 14 familias resistentes (0 % de incidencia al ataque del hongo.

Mapping the future of CIC Division, Los Alamos National Laboratory. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-01-01

This report summarizes three scenario-based strategic planning workshops run for the CIC Division of the Los Alamos National Laboratory during November and December, 1995. Each of the two-day meetings was facilitated by Northeast Consulting Resources, Inc. (NCRI) of Boston, MA. using the Future Mapping{reg_sign} methodology.

Future analytical provision - Relocation of Sellafield Ltd Analytical Services Laboratory

International Nuclear Information System (INIS)

Newell, B.

2015-01-01

Sellafield Ltd Analytical Services provide an essential view on the environmental, safety, process and high hazard risk reduction performances by analysis of samples. It is the largest and most complex analytical services laboratory in Europe, with 150 laboratories (55 operational) and 350 staff (including 180 analysts). Sellafield Ltd Analytical Services Main Laboratory is in need of replacement. This is due to the age of the facility and changes to work streams. This relocation is an opportunity to -) design and commission bespoke MA (Medium-Active) cells, -) modify HA (High-Active) cell design to facilitate an in-cell laboratory, -) develop non-destructive techniques, -) open light building for better worker morale. The option chosen was to move the activities to the NNL Central laboratory (NNLCL) that is based at Sellafield and is the UK's flagship nuclear research and development facility. This poster gives a time schedule

Alumni careers : MA Comparative European Social Studies Zuyd University

OpenAIRE

Riga, Albert

2004-01-01

In the preparation of the celebration of the 10th anniversary of the MA CESS all alumni were invited to participate in an alumni survey. The purpose of the survey was to thoroughly investigate the professional activities of MA CESS alumni and the way they build an alumni community. Another reason for starting the project is that it may play a part in maintaining and enhancing a mutually beneficial relationship between MA CESS and its alumni. All over Europe there are graduates working in the ...

Autoclaving practice in microbiology laboratories: report of a survey. The Public Health Laboratory Service Subcommittee on laboratory autoclaves.

Science.gov (United States)

1978-01-01

The performance of autoclaves in 27 laboratories, operated in accordance with the normal routine of local practice, has been monitored using thermometric equipment. Sterilising performance was unsatisfactory on 10 of 62 occasions, and cooling was inadequate on 52 of 60 occasions. PMID:649767

Reducción de niveles de fumonisinas en grano de maíz protegido de insectos

Directory of Open Access Journals (Sweden)

Jacqueline Cea

2011-04-01

Full Text Available La biotecnología ha hecho posible el desarrollo de híbridos de maíz que están protegidos de insectos lepidópteros barrenadores, mediante la introducción de la secuencia codificante para la proteína Cry1Ab , derivada de  Bacillus thuringiensis (Bt. Estos híbridos se cultivan en diferentes países a partir de 1998, con una adopción que ha llegado al 14% (11.2 millones de hectáreas del área global en 2004 (ISAAA.Existe evidencia de un beneficio adicional derivado de esta  tecnología, en cuanto a la reducción de micotoxinas observada en el grano de estos maíces, atribuída al menor daño provocado por los insectos, considerado una vía de entrada para Fusarium, responsable de la síntesis de fumonisinas. Para este estudio, se llevaron a cabo ensayos de campo en los EEUU, Francia, Argentina y Turquía.Las muestras de granos tomadas fueron sometidas a análisis de micotoxinas en diferentes laboratorios especializados. LATU fue elegido para procesar y analizar las muestras provenientes de ensayos realizados en Argentina.Los  ensayos promediados de los EEUU mostraron una reducción del 46% respecto de los controles no transgénicos. En Argentina, se observaron reducciones de hasta un 60% . En Francia y Turquía  también se mantuvo la tendencia observada, con niveles hasta 7 veces menores en los maíces Bt respecto de los híbridos convencionales. La reducción en los niveles de fumonisinas   al conseguir un grano sano tiene implicancias para la salud en países productores de maíz  con problemas de micotoxinas, y en los cuales el maíz representa una fuente de proteínas importante en la dieta.

Cell cycle-dependent SUMO-1 conjugation to nuclear mitotic apparatus protein (NuMA)

Energy Technology Data Exchange (ETDEWEB)

Seo, Jae Sung; Kim, Ha Na; Kim, Sun-Jick; Bang, Jiyoung; Kim, Eun-A; Sung, Ki Sa [Department of Biological Sciences, Sungkyunkwan University, Suwon 440-746 (Korea, Republic of); Yoon, Hyun-Joo [TissueGene Inc. 9605 Medical Center Dr., Rockville, MD 20850 (United States); Yoo, Hae Yong [Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Samsung Medical Center, Sungkyunkwan University, Seoul 135-710 (Korea, Republic of); Choi, Cheol Yong, E-mail: choicy@skku.ac.kr [Department of Biological Sciences, Sungkyunkwan University, Suwon 440-746 (Korea, Republic of)

2014-01-03

Highlights: •NuMA is modified by SUMO-1 in a cell cycle-dependent manner. •NuMA lysine 1766 is the primary target site for SUMOylation. •SUMOylation-deficient NuMA induces multiple spindle poles during mitosis. •SUMOylated NuMA induces microtubule bundling. -- Abstract: Covalent conjugation of proteins with small ubiquitin-like modifier 1 (SUMO-1) plays a critical role in a variety of cellular functions including cell cycle control, replication, and transcriptional regulation. Nuclear mitotic apparatus protein (NuMA) localizes to spindle poles during mitosis, and is an essential component in the formation and maintenance of mitotic spindle poles. Here we show that NuMA is a target for covalent conjugation to SUMO-1. We find that the lysine 1766 residue is the primary NuMA acceptor site for SUMO-1 conjugation. Interestingly, SUMO modification of endogenous NuMA occurs at the entry into mitosis and this modification is reversed after exiting from mitosis. Knockdown of Ubc9 or forced expression of SENP1 results in impairment of the localization of NuMA to mitotic spindle poles during mitosis. The SUMOylation-deficient NuMA mutant is defective in microtubule bundling, and multiple spindles are induced during mitosis. The mitosis-dependent dynamic SUMO-1 modification of NuMA might contribute to NuMA-mediated formation and maintenance of mitotic spindle poles during mitosis.

Edge pedestal characteristics in JET and JT-60U tokamaks under variable toroidal field ripple

NARCIS (Netherlands)

Urano, H.; Saibene, G.; Oyama, N.; Parail, V.; P. de Vries,; Sartori, R.; Kamada, Y.; Kamiya, K.; Loarte, A.; Lonnroth, J.; Sakamoto, Y.; Salmi, A.; Shinohara, K.; Takenaga, H.; Yoshida, M.

2011-01-01

The effects of toroidal field (TF) ripple on the edge pedestal characteristics were examined in the TF ripple scan experiments at the plasma current I(p) of 1.1 MA in JET and JT-60U. The TF ripple amplitude delta(R) was defined as a value averaged over the existing ripple wells at the separatrix on

Iranian Light Source Facility, A third generation light source laboratory

Directory of Open Access Journals (Sweden)

J Rahighi

2015-09-01

Full Text Available The Iranian Light Source Facility (ILSF project is the first large scale accelerator facility which is currently under planning in Iran. On the basis of the present design, circumference of the 3 GeV storage ring is 528 m. Beam current and natural beam emittance are 400 mA and 0.477 nm.rad, respectively. Some prototype accelerator components such as high power solid state radio frequency amplifiers, low level RF system, thermionic RF gun, H-type dipole and quadruple magnets, magnetic measurement laboratory and highly stable magnet power supplies have been constructed at ILSF R&D laboratory

MaGate Simulator: A Simulation Environment for a Decentralized Grid Scheduler

Science.gov (United States)

Huang, Ye; Brocco, Amos; Courant, Michele; Hirsbrunner, Beat; Kuonen, Pierre

This paper presents a simulator for of a decentralized modular grid scheduler named MaGate. MaGate’s design emphasizes scheduler interoperability by providing intelligent scheduling serving the grid community as a whole. Each MaGate scheduler instance is able to deal with dynamic scheduling conditions, with continuously arriving grid jobs. Received jobs are either allocated on local resources, or delegated to other MaGates for remote execution. The proposed MaGate simulator is based on GridSim toolkit and Alea simulator, and abstracts the features and behaviors of complex fundamental grid elements, such as grid jobs, grid resources, and grid users. Simulation of scheduling tasks is supported by a grid network overlay simulator executing distributed ant-based swarm intelligence algorithms to provide services such as group communication and resource discovery. For evaluation, a comparison of behaviors of different collaborative policies among a community of MaGates is provided. Results support the use of the proposed approach as a functional ready grid scheduler simulator.

Outcomes of iris-claw anterior chamber versus iris-fixated foldable intraocular lens in subluxated lens secondary to Marfan syndrome.

Science.gov (United States)

Hirashima, Denise E; Soriano, Eduardo S; Meirelles, Rodrigo L; Alberti, Gustave N; Nosé, Walton

2010-08-01

To compare the outcome of phacoemulsification using 2 different iris-fixation techniques for intraocular lens (IOL) replacement, a foldable posterior chamber IOL (PCIOL; AcrySof MA60AC, Alcon Laboratories Inc, Fort Worth, TX) and an iris-claw anterior chamber IOL (ACIOL; Artisan, Ophtec BV), for treatment of subluxated lenses in patients with Marfan syndrome (MFS). Randomized, controlled trial. A total of 31 eyes of 16 patients with subluxated lenses associated with MFS and a preoperative corrected visual acuity (CVA) IOL type. Preoperative and postoperative ophthalmologic examination, optical coherence tomography, and endothelial cell counts were performed. We recorded CVA results at 3, 6, and 12 months, complications, endothelial cell loss, and central retinal thickness. In the iris-fixated PCIOL group, CVA was significantly improved at 3 (P = 0.011; n = 16), 6 (P = 0.006; n = 16), and 12 months (P = 0.002; n = 16). In the iris-claw ACIOL group, CVA was significantly improved at 3 (P = 0.001; n=15), 6 (P = 0.001; n = 15), and 12 months (P = 0.009; n = 12). The CVA results did not differ significantly between groups. Dislocation of the IOL occurred in 3 of 16 (18.75%) eyes in the PCIOL group. Retinal detachment occurred in 3 eyes (2 in the PCIOL group and 1 in the ACIOL group) and was successfully repaired. Postoperative foveal tomograms in both groups revealed a decrease in the mean foveal thickness (MFT; IOL dislocation tended to occur more frequently in the iris-fixated PCIOL group, the difference was not significant. At 6 months postoperatively, all study patients tended to have a thinner MFT. None of the patients in either group developed cystoid macular edema. Copyright 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

Status of the Brookhaven National Laboratory (BNL) toroidal volume H- source

International Nuclear Information System (INIS)

Alessi, J.G.; Prelec, K.

1990-01-01

A volume H - source having a toroidal discharge chamber and conical filter field has been developed. Parametric studies of this source have been in progress for two years. Extraction apertures from 0.5 cm 2 to 1.87 cm 2 have been tried, and an H - current of up to 48 mA has been extracted. The electron-to-H - current ratio in the extracted beam can be as low as 10 for ∼ 25 mA beam was 0.44πmm mrad. When operating with deuterium, the D - output wads 50--60% of the H - current under the same discharge conditions. The addition of cesium to the discharge increased the H - output and decreased the electron current so that at 30 mA of H - , one obtained an electron-to-H - ratio of 1. Using a two gap extractor, with a dipole field in the intermediate electrode, approximately 80% of the extracted electrons could be removed from the primary beam

Texture and anisotropy of the mechanical properties of MA14 and MA2-1 alloys produced by granular metallurgy

Science.gov (United States)

Betsofen, S. Ya.; Konkevich, V. Yu.; Osintsev, O. E.; Avdyukhina, A. A.; Voskresenskaya, I. I.; Grushin, I. A.

2015-10-01

The contribution of texture to the anisotropy of the mechanical properties of semifinished products from MA14 and MA2-1 alloys prepared by capsule-free pressing of granules is quantitatively evaluated using inverse pole figures and calculated Taylor orientation factors for basal slip. It is shown that the texture intensity and the anisotropy of the mechanical properties of the pressed semiproducts are lower than those of the semiproducts from an ingot and the compressive yield strength is substantially higher.

Model for Analysis of Energy Demand (MAED-2). User's manual

International Nuclear Information System (INIS)

2007-01-01

The IAEA has been supporting its Member States in the area of energy planning for sustainable development. Development and dissemination of appropriate methodologies and their computer codes are important parts of this support. This manual has been produced to facilitate the use of the MAED model: Model for Analysis of Energy Demand. The methodology of the MAED model was originally developed by. B. Chateau and B. Lapillonne of the Institute Economique et Juridique de l'Energie (IEJE) of the University of Grenoble, France, and was presented as the MEDEE model. Since then the MEDEE model has been developed and adopted to be appropriate for modelling of various energy demand system. The IAEA adopted MEDEE-2 model and incorporated important modifications to make it more suitable for application in the developing countries, and it was named as the MAED model. The first version of the MAED model was designed for the DOS based system, which was later on converted for the Windows system. This manual presents the latest version of the MAED model. The most prominent feature of this version is its flexibility for representing structure of energy consumption. The model now allows country-specific representations of energy consumption patterns using the MAED methodology. The user can now disaggregate energy consumption according to the needs and/or data availability in her/his country. As such, MAED has now become a powerful tool for modelling widely diverse energy consumption patterns. This manual presents the model in details and provides guidelines for its application

Model for Analysis of Energy Demand (MAED-2). User's manual

International Nuclear Information System (INIS)

2006-01-01

The IAEA has been supporting its Member States in the area of energy planning for sustainable development. Development and dissemination of appropriate methodologies and their computer codes are important parts of this support. This manual has been produced to facilitate the use of the MAED model: Model for Analysis of Energy Demand. The methodology of the MAED model was originally developed by. B. Chateau and B. Lapillonne of the Institute Economique et Juridique de l'Energie (IEJE) of the University of Grenoble, France, and was presented as the MEDEE model. Since then the MEDEE model has been developed and adopted to be appropriate for modelling of various energy demand system. The IAEA adopted MEDEE-2 model and incorporated important modifications to make it more suitable for application in the developing countries, and it was named as the MAED model. The first version of the MAED model was designed for the DOS based system, which was later on converted for the Windows system. This manual presents the latest version of the MAED model. The most prominent feature of this version is its flexibility for representing structure of energy consumption. The model now allows country-specific representations of energy consumption patterns using the MAED methodology. The user can now disaggregate energy consumption according to the needs and/or data availability in her/his country. As such, MAED has now become a powerful tool for modelling widely diverse energy consumption patterns. This manual presents the model in details and provides guidelines for its application

Large area imaging of forensic evidence with MA-XRF.

Science.gov (United States)

Langstraat, Kirsten; Knijnenberg, Alwin; Edelman, Gerda; van de Merwe, Linda; van Loon, Annelies; Dik, Joris; van Asten, Arian

2017-11-08

This study introduces the use of macroscopic X-ray fluorescence (MA-XRF) for the detection, classification and imaging of forensic traces over large object areas such as entire pieces of clothing and wall paneling. MA-XRF was sufficiently sensitive and selective to detect human biological traces like blood, semen, saliva, sweat and urine on fabric on the basis of Fe, Zn, K, Cl and Ca elemental signatures. With MA-XRF a new chemical contrast is introduced for human stain detection and this can provide a valuable alternative when the evidence item is challenging for conventional techniques. MA-XRF was also successfully employed for the chemical imaging and classification of gunshot residues (GSR). The full and non-invasive elemental mapping (Pb, Ba, Sr, K and Cl) of intact pieces of clothing allows for a detailed shooting incident reconstruction linking firearms and ammunition to point of impact and providing information on the shooting angle. In high resolution mode MA-XRF can even be used to provide information on the shooting order of different ammunition types. Finally, by using the surface penetration of X-rays we demonstrate that the lead signature of a bullet impact can be easily detected even if covered by multiple layers of wall paint or human blood.

MaGa, a web-based collaborative database for gas emissions: a tool to improve the knowledge on Earth degassing

Science.gov (United States)

Frigeri, A.; Cardellini, C.; Chiodini, G.; Frondini, F.; Bagnato, E.; Aiuppa, A.; Fischer, T. P.; Lehnert, K. A.

2014-12-01

The study of the main pathways of carbon flux from the deep Earth requires the analysis of a large quantity and variety of data on volcanic and non-volcanic gas emissions. Hence, there is need for common frameworks to aggregate available data and insert new observations. Since 2010 we have been developing the Mapping Gas emissions (MaGa) web-based database to collect data on carbon degassing form volcanic and non-volcanic environments. MaGa uses an Object-relational model, translating the experience of field surveyors into the database schema. The current web interface of MaGa allows users to browse the data in tabular format or by browsing an interactive web-map. Enabled users can insert information as measurement methods, instrument details as well as the actual values collected in the field. Measurements found in the literature can be inserted as well as direct field observations made by human-operated instruments. Currently the database includes fluxes and gas compositions from active craters degassing, diffuse soil degassing and fumaroles both from dormant volcanoes and open-vent volcanoes from literature survey and data about non-volcanic emission of the Italian territory. Currently, MaGa holds more than 1000 volcanic plume degassing fluxes, data from 30 sites of diffuse soil degassing from italian volcanoes, and about 60 measurements from fumarolic and non volcanic emission sites. For each gas emission site, the MaGa holds data, pictures, descriptions on gas sampling, analysis and measurement methods, together with bibliographic references and contacts to researchers having experience on each site. From 2012, MaGa developments started to be focused towards the framework of the Deep Earth Carbon Degassing research initiative of the Deep Carbon Observatory. Whithin the DECADE initiative, there are others data systems, as EarthChem and the Smithsonian Institution's Global Volcanism Program. An interoperable interaction between the DECADE data systems is being

Large area imaging of forensic evidence with MA-XRF

NARCIS (Netherlands)

Langstraat, K.; Knijnenberg, A.; Edelman, G.; van de Merwe, L.; van Loon, A.; Dik, J.; van Asten, A.

2017-01-01

This study introduces the use of macroscopic X-ray fluorescence (MA-XRF) for the detection, classification and imaging of forensic traces over large object areas such as entire pieces of clothing and wall paneling. MA-XRF was sufficiently sensitive and selective to detect human biological traces

Large area imaging of forensic evidence with MA-XRF

NARCIS (Netherlands)

Langstraat, Kirsten; Knijnenberg, Alwin; Edelman, Gerda; Van De Merwe, Linda; van Loon, A.; Dik, J.; van Asten, Arian C.

2017-01-01

This study introduces the use of macroscopic X-ray fluorescence (MA-XRF) for the detection, classification and imaging of forensic traces over large object areas such as entire pieces of clothing and wall paneling. MA-XRF was sufficiently sensitive and selective to detect human biological traces

Usporedba antibakterijske i antigljivične učinkovitosti otopina za dezinfekciju mekih kontaktnih leća

OpenAIRE

Kuzman, Tomislav; Pokupec, Rajko; Kalauz, Miro; Juri, Jelena; Bujger, Zdenko; Presečki, Aleksandra

2008-01-01

Cilj studije bio je usporediti antibakterijska i antigljivična svojstva pet tekućina za dezinfekciju mekih kontaktnih leća. Ispitane su slijedeće tekućine: Oxysept Comfort (Advanced Medical Optics), Nitilens One Step (Avizor), Opti-Free Express (Alcon Laboratories), Complete Moisture Plus (Advanced Medical Optics) i Nitilens All-in-one (Avizor). Usporedili smo njihovu učinkovitost u dezinfekciji fiziološke otopine eksperimentalno kontaminirane slijedećim mikroorganizmima (American Type Cultur...

Separation of minor actinides from a genuine MA/LN fraction

International Nuclear Information System (INIS)

Satmark, B.; Courson, O.; Malmbeck, R.; Pagliosa, G.; Romer, K.; Glatz, J.P.

2001-01-01

Separation of the trivalent Minor Actinides (MA), Am and Cm, has been performed from a genuine MA(III) + Ln(III) solution using Bis-Triazine-Pyridine (BTP) as organic extractant. The representative MA/Ln fraction was obtained from a dissolved commercial LWR fuel (45.2 GWd/tM) submitted subsequently too a PUREX process followed by a DIAMEX process. A centrifugal extractor set-up (16-stages), working in a continuous counter-current mode, was used for the liquid-liquid separation. In the nPr-BTP process, feed decontamination factors for Am and Cm above 96 and 65, respectively were achieved. The back-extraction was more efficient for Am (99.1% recovery) than for Cm (97.5%). This experiment, using the Bis-Triazine-Pyridine molecule is the first successful demonstration of the separation of MA from lanthanides in a genuine MA/Ln fraction with a nitric acid concentration of ca. 1 M. It represents an important break through in the difficult field of minor actinide partitioning of high level liquid waste. (author)

Diet of Theropithecus from 4 to 1 Ma in Kenya.

Science.gov (United States)

Cerling, Thure E; Chritz, Kendra L; Jablonski, Nina G; Leakey, Meave G; Manthi, Fredrick Kyalo

2013-06-25

Theropithecus was a common large-bodied primate that co-occurred with hominins in many Plio-Pleistocene deposits in East and South Africa. Stable isotope analyses of tooth enamel from T. brumpti (4.0-2.5 Ma) and T. oswaldi (2.0-1.0 Ma) in Kenya show that the earliest Theropithecus at 4 Ma had a diet dominated by C4 resources. Progressively, this genus increased the proportion of C4-derived resources in its diet and by 1.0 Ma, had a diet that was nearly 100% C4-derived. It is likely that this diet was comprised of grasses or sedges; stable isotopes cannot, by themselves, give an indication of the relative importance of leaves, seeds, or underground storage organs to the diet of this primate. Theropithecus throughout the 4- to 1-Ma time range has a diet that is more C4-based than contemporaneous hominins of the genera Australopithecus, Kenyanthropus, and Homo; however, Theropithecus and Paranthropus have similar proportions of C4-based resources in their respective diets.

Avatares tántricos de Râma

OpenAIRE

Muñoz, Adrián

2009-01-01

Si bien el poema épico del Râmâyana es considerado como uno de los pilares literarios del hinduismo, no se trata de un texto fijo, pues la trama ha generado diversas versiones alternas en el sur y el sureste asiáticos. Al mismo tiempo, aunque Râma representa ideales sociales fundamentales para la ortodoxia hinduista, otras corrientes religiosas no ortodoxas han recurrido a y adaptado la figura de Râma. Este ensayo busca valorar en particular las manifestaciones tántricas y pseudo-tántrica...

60 Myr records of major elements and Pb-Nd isotopes from hydrogenous ferromanganese crusts: Reconstruction of seawater paleochemistry

Digital Repository Service at National Institute of Oceanography (India)

Frank, M.; O'Nions, R.K.; Hein, J.R.; Banakar, V.K.

- and Co-based dating of three Co-rich crusts supports the validity of this approach and confirms the earlier chronologies derived from extrapolated sup(10)Be/ sup(9)Be-based growth rates back to 60 Ma. The data show that the flux of Co into Co-poor crusts...

BaMa / Raivo Juurak

Index Scriptorium Estoniae

Juurak, Raivo, 1949-

2002-01-01

Eesti ülikoolide üleminekust 3+2 süsteemile. Lühend BaMa on tulnud kasutusele seoses Euroopa ülikoolide õppekavade reformimisega ning tähistab õppekava, kus esimese astme läbimise järel omandatakse bakalaureuse- ja teise järel magistrikraad. Õppekavade tüüpidest Eesti ja Euroopa Liidu kõrgkoolides ning Bologna deklaratsioonist

Recent developments in the JT-60 data processing system

International Nuclear Information System (INIS)

Matsuda, T.; Saitoh, N.; Tsugita, T.; Oshima, T.; Sakata, S.; Sato, M.; Koiwa, M.; Watanabe, K.

1999-01-01

The JT-60 data processing system was originally a large computer complex system including a lot of micro-computers, several mini-computers, and a mainframe computer. Recently, several improvements have been made to the original system to modernize the system. Many sub-systems composed of aged mini-computers have been replaced with workstations by utilizing recent progress in computer and network technologies. The system can handle ∝300 MB of raw data per discharge, which is three times larger than the amount in the original system. These improvements have been applied to develop element technologies necessary to the remote participation in JT-60 experiments. A remote diagnostics control and monitoring system and a computer system for access to JT-60 data from the Internet are used together with video conferencing systems for a real-time communication. In 1996, the remote participation based on them was successfully demonstrated in collaboration with Japan Atomic Energy Research Institute, Los Alamos National Laboratory, and Princeton Plasma Physics Laboratory. (orig.)

Impact of M&A on the Employment in Japanese Companies

OpenAIRE

Hiroyuki Taguchi; Taichi Yanagawa; Masashi Harita

2012-01-01

With utilizing Financial Statements Statistics of Corporation by Industry, we analyzed the impact of M&A on the employment in Japanese companies. In this study, the impact of M&A on the employment was extracted by developing panel data for fiscal year 1995 to 2008 targeting 9,880 sample companies including 3,697 cases of M&A to estimate a labor demand model. Major findings of the study are described below. First, dynamically positive effect was confirmed mainly in the manufacturing industry a...

Convective removal of the Tibetan Plateau mantle lithosphere by 26 Ma

Science.gov (United States)

Lu, Haijian; Tian, Xiaobo; Yun, Kun; Li, Haibing

2018-04-01

During the late Oligocene-early Miocene there were several major geological events in and around the Tibetan Plateau (TP). First, crustal shortening deformation ceased completely within the TP before 25 Ma and instead adakitic rocks and potassic-ultrapotassic volcanics were emplaced in the Lhasa terrane since 26-25 Ma. Several recent paleoelevation reconstructions suggest an Oligocene-early Miocene uplift of 1500-3000 m for the Qiangtang (QT) and Songpan-Ganzi (SG) terranes, although the exact timing is unclear. As a possible response to this uplift, significant desertification occurred in the vicinity of the TP at 26-22 Ma, and convergence between India and Eurasia slowed considerably at 26-20 Ma. Subsequently, E-W extension was initiated no later than 18 Ma in the Lhasa and QT terranes. In contrast, the tectonic deformation around the TP was dominated by radial expansion of shortening deformation since 25-22 Ma. The plateau-wide near-synchroneity of these events calls for an internally consistent model which can be best described as convective removal of the lower mantle lithosphere. Geophysical and petrochemical evidence further confirms that this extensive removal occurred beneath the QT and SG terranes. The present review concludes that, other than plate boundary stress, the internal stress within the TP lithosphere could have contributed to rapid wholesale uplift and a series of concomitant tectonic events, accompanied by major aridification, since 26 Ma.

Alumni careers : MA Comparative European Social Studies Zuyd University

NARCIS (Netherlands)

Albert Riga

2004-01-01

In the preparation of the celebration of the 10th anniversary of the MA CESS all alumni were invited to participate in an alumni survey. The purpose of the survey was to thoroughly investigate the professional activities of MA CESS alumni and the way they build an alumni community. Another reason

42 CFR 422.2268 - Standards for MA organization marketing.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Standards for MA organization marketing. 422.2268 Section 422.2268 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Medicare Advantage Marketing Requirements § 422.2268 Standards for MA organizatio...

Geist, Logik, Kapital und die Technik des Maßes

Directory of Open Access Journals (Sweden)

Frank Engster

2017-02-01

Full Text Available Hegels Phänomenologie des Geistes (PhdG und seine Wissenschaft der Logik (WdL sowie Marx Kapital sind, so wird im ersten Teil gezeigt, jeweils Ausdruck einer Verlegenheit. Alle drei stehen nämlich vor der Herausforderung, in Geist, Logik und Kapital letztlich eine Methode darstellen zu müssen, und sie müssen darüber auch noch die Möglichkeit der Darstellung ebendieser Methode einholen und begründen. Diese Übereinkunft zwischen der Methode der Darstellung mit dem Methodischen aufseiten des dargestellten Geistes, der Logik und des Kapitals gelingt, so die These des zweiten Teils, durch die Technik des Maßes. Maß und Messung konstituieren bereits in der Naturwissenschaft Objektivität im neuzeitlichen Sinne: Gehalten an und gebrochen durch ihre eigenen Maß, werden die Verhältnisse der Natur durch die ermittelten Werte wie ein selbständiger Gegenstand objektiv bestimmbar und im Wissen subjektiv aufgehoben. Dagegen zeigen Geist, Logik und Kapital jeweils, dass die Technik des Maßes nicht nur Objektivität im neuzeitlichen Sinne konstituiert, sondern die gesamte neuzeitliche Form der Gegenständlichkeit von Objektivität und Subjektivität, Bewusstsein und Gegenstand. In Hegels Phänomenologie und seiner Logik sowie in Marx Kapital eröffnet das Maß diese Gegenständlichkeit, indem jeweils eine Objektivität konstituiert wird, die einem Subjekt buchstäblich zu denken gegeben wird. Es ist allerdings unmittelbar die Objektivität der Subjektivität selbst, die jeweils gegeben wird: phänomenologisch wird durch das Maß die Objektivität der Subjektivität des Geistes gegeben (PhdG, rein logisch wird die Objektivität des Seins durch die Subjektivität des Begriffs gegeben (WdL, und der kapitalistischen Gesellschaft ist durch quantitative Werte die eigene Objektivität gegeben, und zwar gegeben durch ein Geld, das dadurch zu einer überindividuellen, automatischen Subjektivität wird. Für das Maß steht in der Phänomenologie das

MaRGEE: Move and Rotate Google Earth Elements

Science.gov (United States)

Dordevic, Mladen M.; Whitmeyer, Steven J.

2015-12-01

Google Earth is recognized as a highly effective visualization tool for geospatial information. However, there remain serious limitations that have hindered its acceptance as a tool for research and education in the geosciences. One significant limitation is the inability to translate or rotate geometrical elements on the Google Earth virtual globe. Here we present a new JavaScript web application to "Move and Rotate Google Earth Elements" (MaRGEE). MaRGEE includes tools to simplify, translate, and rotate elements, add intermediate steps to a transposition, and batch process multiple transpositions. The transposition algorithm uses spherical geometry calculations, such as the haversine formula, to accurately reposition groups of points, paths, and polygons on the Google Earth globe without distortion. Due to the imminent deprecation of the Google Earth API and browser plugin, MaRGEE uses a Google Maps interface to facilitate and illustrate the transpositions. However, the inherent spatial distortions that result from the Google Maps Web Mercator projection are not apparent once the transposed elements are saved as a KML file and opened in Google Earth. Potential applications of the MaRGEE toolkit include tectonic reconstructions, the movements of glaciers or thrust sheets, and time-based animations of other large- and small-scale geologic processes.

PERIGOSIDADE A CHEIAS NO RIO UÍMA (SANTA MARIA DA FEIRA, PORTUGAL: ENSAIO METODOLÓGICO DE SUPORTE À IMPLEMENTAÇÃO DA DIRETIVA 2007/60/CE

Directory of Open Access Journals (Sweden)

Inês Marafuz

2014-12-01

Full Text Available O aumento dos episódios de cheias e consequentes perdas humanas e prejuízos materiais tem conduzido a uma crescente preocupação por parte dos governos europeus e das autoridades nacionais que lidam com estas questões. Neste contexto, a aprovação da Diretiva 2007/60/CE estabeleceu a necessidade de se efetuar uma avaliação preliminar do risco de inundação e de se produzir cartografia de apoio à minimização dos efeitos destes eventos. Neste artigo apresenta-se um ensaio metodológico para a determinação da perigosidade a cheias num setor do rio Uíma (norte de Portugal, através da aplicação de uma matriz de intensidade-probabilidade. Esta matriz relaciona os parâmetros da velocidade e da altura da coluna de água, modelados no software Hec-Ras, com a frequência de ocorrência de cheias. No final identificaram-se, por classe de perigosidade, os elementos expostos, designadamente o edificado e as estradas. Os resultados mostram que as diferenças nos perímetros de inundação para os períodos de retorno considerados (10, 50 e 100 anos se destacam na área central da planície aluvial modelada. A altura da coluna de água apresenta valores mais elevados nos segmentos do rio a montante das pontes, que funcionam como barreiras à circulação da água. A velocidade da água é elevada nesses mesmos segmentos e no setor a montante, onde o vale é mais estreito. Pela conjugação destes fatores e da recorrência dos eventos, verifica-se que a perigosidade a cheias é mais elevada nos setores atravessados por pontes e no início do setor modelado. A metodologia aplicada visa ser um contributo para os municípios portugueses que terão de dispor de cartografia de áreas inundáveis similar à que se apresenta neste trabalho de forma a cumprirem o estipulado na Diretiva 2007/60/CE.

Design, fabrication and test of double-wall vacuum vessel for JT-60U

International Nuclear Information System (INIS)

Uchikawa, Takashi; Ioki, Kimihiro; Ninomiya, Hiromasa.

1994-01-01

A double-wall vacuum vessel was designed and fabricated for JT-60U (an upgraded machine of JT-60), which has a plasma current up to 6 MA and a large plasma volume (100 m 3 ). A new concept of Inconel 625 all-welded structure was adopted to the vessel, that comprises an inner plate, square tubes and an outer plate. The vacuum vessel with a multi-arc D-shaped cross section was fabricated by using hot-sizing press. The electromagnetic and structural analysis has been performed for plasma disruption loads. Dynamic responses of the vessel were measured during plasma disruptions, and the observed displacement had a good agreement with the result of FEM analysis. (author)

Studiju programmas direktora informatīvā sistēma

OpenAIRE

Gūtmanis, Matīss

2012-01-01

Šajā kvalifikācijas darbā tiek izstrādāta atbalsta sistēma studiju programmas direktoram pamata informācijas glabāšanai. Sistēma tiek plānota kā tīmekļa lietotne, kas ir brīvi pieejama ikvienam. Lietotne ir izstrādāta izmantojot JAVA, HTML, JavaScript, MySQL tehnoloģijas. Sistēma paredzēta Latvijas Universitātes Datorikas Fakultātes programmu direktoriem.

Sesli Okuma ve Konuşma Prozodisi: İlişkisel Bir Çalışma

Directory of Open Access Journals (Sweden)

Hasan Keskin

2013-02-01

Full Text Available Bu araştırma,  ilköğretim dördüncü sınıf öğrencilerinin sesli okuma ve konuşma prozodileri arasındaki ilişkiyi incelemek amacıyla ilişkisel tarama modelinde yapılmıştır. Araştırmaya,  Konya ve Afyonkarahisar’da ilköğretim dördüncü sınıfa devam eden 50 öğrenci katılmıştır.  Öğrencilerin sesli okumaları ve konuşmaları video ile kayıt altına alınmış, daha sonra bu kayıtlar üzerinde ölçekler aracılığıyla puanlamalar yapılmıştır. Sesli okuma ve konuşma prozodisi arasındaki ilişkiyi belirlemeye yönelik, Pearson Momentler Çarpım Korelasyon Tekniği kullanılmıştır. Analiz sonuçlarına göre, öğrencilerin sesli okuma ve konuşma prozodileri arasında, pozitif yönlü orta düzeyde bir ilişki çıkmıştır. Öğrencilerin sesli okumaları ve konuşma prozodi puanları cinsiyet açısından ayrı ayrı incelenmiş; kız ve erkek öğrencilerin ortalamaları arasında anlamlı bir farklılık çıkmamıştır. Ayrıca, öğrencilerin sesli okuma ve konuşmalarındaki prozodik düzeyi belirlemeye yönelik ölçümler yapılmıştır. Bu ölçüm sonuçlarına göre, araştırmaya katılan öğrencilerin %52’sinin sesli okuma prozodilerinin,  %48’inin ise konuşma prozodilerinin düşük düzeyde olduğu görülmüştür.

Where is the happy Ending of Shāhnāma?

OpenAIRE

بهروز چمن آرا

2015-01-01

The renowned proverb “Shāhnāma axarash xoš ast” has implicit question which its answer may change our understanding of the nature and function of Shāhnāma. The end of Shāhnāma contains numerous tragic events in Sassanid age. Also it does not seem to be normal if the Iranians have deemed the bitter adventure of the Shahs and Pahlavāns as a happy ending like what Firdausi narrates at the end of his Shāhnāma. This article tries to reply the main question using an illustration on the story platfo...

Comprehensive analysis of NuMA variation in breast cancer

Directory of Open Access Journals (Sweden)

Aittomäki Kristiina

2008-03-01

Full Text Available Abstract Background A recent genome wide case-control association study identified NuMA region on 11q13 as a candidate locus for breast cancer susceptibility. Specifically, the variant Ala794Gly was suggested to be associated with increased risk of breast cancer. Methods In order to evaluate the NuMa gene for breast cancer susceptibility, we have here screened the entire coding region and exon-intron boundaries of NuMa in 92 familial breast cancer patients and constructed haplotypes of the identified variants. Five missense variants were further screened in 341 breast cancer cases with a positive family history and 368 controls. We examined the frequency of Ala794Gly in an extensive series of familial (n = 910 and unselected (n = 884 breast cancer cases and controls (n = 906, with a high power to detect the suggested breast cancer risk. We also tested if the variant is associated with histopathologic features of breast tumors. Results Screening of NuMA resulted in identification of 11 exonic variants and 12 variants in introns or untranslated regions. Five missense variants that were further screened in breast cancer cases with a positive family history and controls, were each carried on a unique haplotype. None of the variants, or the haplotypes represented by them, was associated with breast cancer risk although due to low power in this analysis, very low risk alleles may go unrecognized. The NuMA Ala794Gly showed no difference in frequency in the unselected breast cancer case series or familial case series compared to control cases. Furthermore, Ala794Gly did not show any significant association with histopathologic characteristics of the tumors, though Ala794Gly was slightly more frequent among unselected cases with lymph node involvement. Conclusion Our results do not support the role of NuMA variants as breast cancer susceptibility alleles.

Comprehensive analysis of NuMA variation in breast cancer

International Nuclear Information System (INIS)

Kilpivaara, Outi; Rantanen, Matias; Tamminen, Anitta; Aittomäki, Kristiina; Blomqvist, Carl; Nevanlinna, Heli

2008-01-01

A recent genome wide case-control association study identified NuMA region on 11q13 as a candidate locus for breast cancer susceptibility. Specifically, the variant Ala794Gly was suggested to be associated with increased risk of breast cancer. In order to evaluate the NuMa gene for breast cancer susceptibility, we have here screened the entire coding region and exon-intron boundaries of NuMa in 92 familial breast cancer patients and constructed haplotypes of the identified variants. Five missense variants were further screened in 341 breast cancer cases with a positive family history and 368 controls. We examined the frequency of Ala794Gly in an extensive series of familial (n = 910) and unselected (n = 884) breast cancer cases and controls (n = 906), with a high power to detect the suggested breast cancer risk. We also tested if the variant is associated with histopathologic features of breast tumors. Screening of NuMA resulted in identification of 11 exonic variants and 12 variants in introns or untranslated regions. Five missense variants that were further screened in breast cancer cases with a positive family history and controls, were each carried on a unique haplotype. None of the variants, or the haplotypes represented by them, was associated with breast cancer risk although due to low power in this analysis, very low risk alleles may go unrecognized. The NuMA Ala794Gly showed no difference in frequency in the unselected breast cancer case series or familial case series compared to control cases. Furthermore, Ala794Gly did not show any significant association with histopathologic characteristics of the tumors, though Ala794Gly was slightly more frequent among unselected cases with lymph node involvement. Our results do not support the role of NuMA variants as breast cancer susceptibility alleles

Large-scale global convection in the mantle beneath Australia from 55 Ma to now

International Nuclear Information System (INIS)

Zhang, M.

1999-01-01

Full text: The global-scale mantle convection cells in the asthenosphere are not geochemically homogeneous. The heterogeneity is most prominently reflected in the isotopic compositions (Pb-Sr-Nd) of the mid-ocean ridge basalts (MORB) that are direct partial melts from the underlying asthenosphere. Of particular relevance to Australia's geodynamic evolution from about 100 million years, are the distinctive geochemical signatures of the asthenosphere beneath the Pacific Ocean (Pacific MORB) and Indian Ocean (Indian MORB). Therefore, delineation of the boundary between the two distinct mantle reservoirs and any change in that boundary with time provide information about the patterns of global-scale asthenospheric mantle convection. This information has also allowed us to track large-scale mantle chemical reservoirs such as the distinctive Gondwana lithospheric mantle, and hence better understand the geodynamic evolution of the Australian continent from the time of Gondwana dispersal. Pb-Sr-Nd isotope data for Cenozoic basalts in eastern Australia (Zhang et al, 1999) indicate that Pacific-MORB type isotopic signatures characterise the lava-field basalts (55-14 Ma) in southeastern Australia, whereas Indian-MORB type isotopic signatures characterise younger basalts (6-0 Ma) from northeastern Australia. This discovery helps to constrain the changing locus of the major asthenospheric mantle convection cells represented by the Pacific and Indian MORB sources during and following the breakup of the eastern part of Gondwana, and locates, for the first time, the boundary of these convection cells beneath the Australian continent. This extends previous work in the SW Pacific back-arc basins (eg Hickey-Vargas et al., 1995) and the Southern Ocean (Lanyon et al., 1995) that indicates that the 1- and P-MORB mantle convection cells have been moving in opposite directions since the early Tertiary. These new data also indicate that the Indian-MORB source is a long-term asthenospheric

"Sel kevadel olen ma eriti ilus..." : [luuletused] / Triin Soomets

Index Scriptorium Estoniae

Soomets, Triin

2003-01-01

Sisu: "Sel kevadel olen ma eriti ilus..." ; "Tahaksin teha midagi tõelist; midagi suurt..." ; "veebruaris on keha nii valge et syda läheb pahaks..." ; "kõige kohutavamad lepingud..." ; "Igal loojangul kutsun sind ja igal koidikul tõukan su ära..." ; "need hakid..." ; "Põhja vajudes on viimane asi, mida ma näen, rohelised sähvatused..."

Construction of a high modulus asphalt (HiMA) trial section Ethekwini: South Africa's first practical experience with design, manufacturing and paving of HiMA

CSIR Research Space (South Africa)

Nkgapele, M

2012-07-01

Full Text Available A trial section was paved with the recently introduced High Modulus Asphalt (HiMA) technology on South Coast road in eThekwini (Durban). The trial section forms part of an effort to transfer HiMA technology to South Africa, in an initiative aimed...

Ma ma (2015. A reflection of the Spanish woman with breast cáncer

Directory of Open Access Journals (Sweden)

Clara PERALTA NUENO

2017-12-01

Full Text Available Ma ma (2015 is a Spanish drama film directed by Julio Medem and produced by Morena Films. This film tells the story of Magda’s life, whose character is interpreted by Penélope Cruz. After being diagnosed with a breast cancer, Magda, an unemployed teacher, will not know how to act nor how this disease will change her life. But little by little, she will bring into the surface all her vital energy. Breast cancer represents the most frequent type of cancer among women. Although the majority of the identified risk factors can be modified, the health systems focus on activities that let strengthen the primary prevention and activities of secondary and tertiary prevention. The early detection and the right treatment are essential to fight against this disease. The emotional process caused by the presence of cancer involves a mechanism of psychic reconstitution that allows the patient develop an answer to the organic, cognitive, social, and emotional challenges they have to deal with. This process is easier when they have a solid socio-family support network among other factors.

Orchiectomy for suspected microscopic tumor in patients with anti-Ma2-associated encephalitis.

Science.gov (United States)

Mathew, R M; Vandenberghe, R; Garcia-Merino, A; Yamamoto, T; Landolfi, J C; Rosenfeld, M R; Rossi, J E; Thiessen, B; Dropcho, E J; Dalmau, J

2007-03-20

To report the presence of microscopic neoplasms of the testis in men with anti-Ma2-associated encephalitis (Ma2-encephalitis) and to discuss the clinical implications. Orchiectomy specimens were examined using immunohistochemistry with Ma2 and Oct4 antibodies. Among 25 patients with Ma2-encephalitis younger than 50 years, 19 had germ-cell tumors, and 6 had no evidence of cancer. These 6 patients underwent orchiectomy because they fulfilled five criteria: 1) demonstration of anti-Ma2 antibodies in association with MRI or clinical features compatible with Ma2-encephalitis, 2) life-threatening or progressive neurologic deficits, 3) age Ma2 was expressed by neoplastic cells in three of three patients examined. Even though most patients had severe neurologic deficits at the time of orchiectomy (median progression of symptoms, 10 months), 4 had partial improvement and prolonged stabilization (8 to 84 months, median 22.5 months) and two did not improve after the procedure. In young men with Ma2-encephalitis, 1) the disorder should be attributed to a germ-cell neoplasm of the testis unless another Ma2-expressing tumor is found, 2) negative tumor markers, ultrasound, body CT, or PET do not exclude an intratubular germ-cell neoplasm of the testis, and 3) if no tumor is found, the presence of the five indicated criteria should prompt consideration of orchiectomy.

Energy confinement in JT-60 lower hybrid current driven plasmas

International Nuclear Information System (INIS)

Ushigusa, K.; Imai, T.; Naito, O.; Ikeda, Y.; Tsuji, S.; Uehara, K.

1990-01-01

The energy confinement in high power lower hybrid current driven (LHCD) plasmas has been studied in the JT-60 tokamak. At a plasma current of 1 MA, the diamagnetically estimated energy confinement time in LHCD plasmas has almost the same value as the confinement time in ohmically heated plasmas at n-bar e ∼ 1.0x10 19 m -3 . The confinement time of high power LHCD plasmas (P LH E varies as to P LH α n e β I p 0 with α + β ∼ -0.3. (author). Letter-to-the-editor. 12 refs, 5 figs

Development of a dispersion strengthened copper alloy using a MA-HIP method

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T. Yamada

2016-12-01

Full Text Available A new Cu-Al alloy was fabricated by a MA-HIP method for application to the heat sink materials of divertors. With the increase in MA time, the grain size and Vickers hardness decreased and increased, respectively. At MA time of 32hrs, the hardness of the alloy was comparable to that of Glidcop® although the grain size was much larger. X-ray diffractometry, electrical resistivity measurements and STEM-EDS analyses suggested precipitation of Al-rich phase by MA for 32hrs followed by HIP.

Avaliação sensorial e determinação de vida-de-prateleira de maçãs desidratadas Sensorial evaluation and determination of dehydrated apple shelf life

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Andressa Regina Vasques

2006-12-01

Full Text Available O objetivo deste trabalho foi determinar a preferência sensorial e vida-de-prateleira de fatias de maçãs das cultivares Fuji e Gala desidratadas. A secagem foi feita à temperatura de 60 °C, com velocidade do ar no interior do secador de bandejas de 0,121 m/s. Para a realização do teste de preferência sensorial e aceitabilidade, mediante uso de uma escala de avaliação, foram utilizadas as maçãs com e sem pré-tratamento, obtendo-se um total de 4 amostras para análise. A maçã com maior índice de aceitação foi a maçã da cultivar Fuji sem tratamento, e a maçã com índice elevado de rejeição foi a maçã Gala sem tratamento, com 25%. De acordo com o resultado da análise sensorial, a vida-de-prateleira experimental das maçãs desidratadas foi determinada para as maçãs Fuji sem pré-tratamento e para as maçãs Gala com tratamento em diferentes tipos e tamanhos de embalagens. Em 360 dias de armazenamento, à temperatura ambiente, observou-se principalmente o significativo aumento do ganho de umidade nas maçãs de ambas as cultivares em embalagens de Polietileno Tereftalato e Copolímero de Cloreto de Vinil e Vinilideno/ Polietileno (Pet Saran/Pe e não se observou diferenças significativas entre as embalagens de Polietileno Tereftalato/Alumínio/Polietileno (Pet/Al/Pe e Polipropileno/Alumínio/Polietileno (PP/Al/Pe.The objective of this work was to determine the sensorial preference and the shelf live of dehydrated Fuji and Gala culture apple slices. Drying was done at a temperature of 60 °C and at an air speed of 0.121 m/s inside the tray dryer. In order to carry out the sensorial preference and acceptability test with the use of an evaluation scale, apples with and without pretreatment were used, resulting in a total of 4 samples for analysis. The apple with the greatest acceptance was the Fuji and the culture apple with a high rejection rate was the Gala without pretreatment, represented by 25% of the 100 people who

Reduction in laboratory turnaround time decreases emergency room length of stay

Directory of Open Access Journals (Sweden)

Kaushik N

2018-04-01

Full Text Available Nitin Kaushik,1 Victor S Khangulov,2 Matthew O’Hara,2 Ramy Arnaout3,4 1Becton, Dickinson and Company, Franklin Lakes, NJ, USA; 2Department of Health Economics and Outcomes Research, Boston Strategic Partners, Inc., Boston, MA, USA; 3Department of Pathology, 4Division of Biomedical Informatics, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA USA Objective: Laboratory tests are an important contributor to treatment decisions in the emergency department (ED. Rapid turnaround of laboratory tests can optimize ED throughout by reducing the length of stay (LOS and improving patient outcomes. Despite evidence supporting the effect of shorter turnaround time (TAT on LOS and outcomes, there is still a lack of large retrospective studies examining these associations. Here, we evaluated the effect of a reduction in laboratory TAT on ED LOS using retrospective analysis of Electronic Health Records (EHR. Materials and methods: Retrospective analysis of ED encounters from a large, US-based, de-identified EHR database and a separate analysis of ED encounters from the EHR of an ED at a top-tier tertiary care center were performed. Additionally, an efficiency model calculating the cumulative potential LOS time savings and resulting financial opportunity due to laboratory TAT reduction was created, assuming other factors affecting LOS are constant. Results: Multivariate regression analysis of patients from the multisite study showed that a 1-minute decrease in laboratory TAT was associated with 0.50 minutes of decrease in LOS. The single-site analysis confirmed our findings from the multisite analysis that a positive correlation between laboratory TAT and ED LOS exists in the ED population as a whole, as well as across different patient acuity levels. In addition, based on the calculations from the efficiency model, for a 5-, 10- and 15-minute TAT reduction, the single-site ED can potentially admit a total of 127, 256 and 386 additional

A prospective, contralateral eye study comparing thin-flap LASIK (sub-Bowman keratomileusis) with photorefractive keratectomy.

Science.gov (United States)

Slade, Stephen G; Durrie, Daniel S; Binder, Perry S

2009-06-01

To determine the differences in the visual results, pain response, biomechanical effect, quality of vision, and higher-order aberrations, among other parameters, in eyes undergoing either photorefractive keratectomy (PRK) or thin-flap LASIK/sub-Bowman keratomileusis (SBK; intended flap thickness of +/-100 microm and 8.5-mm diameter) at 1, 3, and 6 months after surgery. A contralateral eye pilot study. Fifty patients (100 eyes) were enrolled at 2 sites. The mean preoperative spherical refraction was -3.66 diopters (D) and the mean cylinder was -0.66 D for all eyes. Eyes in the PRK group underwent 8.5-mm ethanol-assisted PRK, whereas in eyes in the SBK group, an 8.5-mm, (intended) 100-microm flap was created with a 60-kHz IntraLase femtosecond laser (Advanced Medical Optics, Santa Ana, CA). All eyes underwent a customized laser ablation using an Alcon LADARVision 4000 CustomCornea excimer laser (Alcon Laboratories, Fort Worth, TX). Preoperative and postoperative tests included best spectacle-corrected visual acuity, uncorrected visual acuity (UCVA), corneal topography, wavefront aberrometry, retinal image quality, and contrast sensitivity. Patients completed subjective questionnaires at each visit. One- and 3-month UCVA results showed a statistically significant difference: SBK, 88% 20/20 or better vs. 48% 20/20 or better for PRK. At 6 months, UCVA was 94% 20/20 or better for PRK and 92% for SBK. At 1 and 3 months, the SBK group had lower higher-order aberrations (coma and spherical aberration; PPRK group. By 3 months, the vision in the 2 groups had begun to equalize, although the SBK eyes continued to have better vision. At 6 months, there were no statistical differences between the 2 groups. Proprietary or commercial disclosure may be found after the references.

High performance experiments in JT-60U reversed shear discharges

International Nuclear Information System (INIS)

Fujita, T.; Kamada, Y.; Ishida, S.

2001-01-01

The operation of JT-60U reversed shear discharges has been extended to a high plasma current, low-q regime keeping a large radius of the internal transport barrier (ITB) and the record value of equivalent fusion multiplication factor in JT-60U, Q DT eq =1.25, has been achieved at 2.6 MA. Operational schemes to reach the low-q regime with good reproducibility have been developed. The reduction of Z eff was obtained in the newly installed W-shaped pumped divertor. The beta limit in the low-q min regime, which limited the performance of L-mode edge discharges, has been improved in H-mode edge discharges with a broader pressure profile, which was obtained by power flow control with ITB degradation. Sustainment of ITB and improved confinement for 5.5 seconds has been demonstrated in an ELMy H reversed shear discharge. (author)

Ma olin Saddami poeg / Latif Jahija

Index Scriptorium Estoniae

Jahija, Latif

1995-01-01

Järg Jan/21.,28. lk. 7,5. L. Jahija sensatsiooniline raamat "Ma olin Saddami poeg", milles ta pajatab kuidas ta a. 1987-1991 oli Iraagi presidendi vanema poja teisik. Lühikokkuvõte sellest jutustusest

y comercialización de maíz de Sinaloa

Directory of Open Access Journals (Sweden)

José Alberto García Salazar

2006-01-01

Full Text Available La política comercial instrumentada por el Gobierno de México dirigida al mercado de maíz se ha caracterizado por la autorización de importaciones libres de arancel superiores a la cuota establecida en el Tratado de Libre Comercio de América del Norte. Con el objetivo de analizar cómo esta política podría afectar la comercialización de la producción de maíz de Sinaloa, se usó un modelo de distribución de la producción del grano que incorpora características espaciales e intertemporales. Los resultados indican que si el consumo nacional real de maíz fuera menor en 10%, respecto al consumo nacional aparente, las mayores importaciones determinarían que 954 mil toneladas de la producción de la entidad no pudrían comercializarse. Debido a que esta situación resta competitividad al productor de maíz, puesto que la producción no comercializada tiene que almacenarse, los productores sinaloenses deberán estar pendientes y vigilar las decisiones del Gobierno en materia de cupos de importación de maíz.

46 CFR 308.306 - Second Seamen's War Risk Policy, Form MA-242.

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Second Seamen's War Risk Policy, Form MA-242. 308.306... RISK INSURANCE Second Seamen's War Risk Insurance § 308.306 Second Seamen's War Risk Policy, Form MA-242. (a) The standard form of Second Seamen's War Risk Policy Form MA-242, may be obtained from the...

Características y propiedades funcionales del maíz morado (Zea mays L. var. subnigroviolaceo

Directory of Open Access Journals (Sweden)

Jhoseline Guillén-Sánchez

2014-01-01

Full Text Available Elmaíz morado es una planta oriunda de América, que tieneel epispermo de las semillas (granos y la tusa(coronta de color morado, lo que le otorga características especiales a los pigmentos que poseen (entre 1,5% y6,0%, llamados antocianinas, que pertenecen al grupo delosflavonoides.Debido a su altocontenido deantocianinas (cianin-3-glucosa C3G que es su principal colorante y compuestos fenólicosactúa como unpoderoso antioxidante natural y anticancerígeno, teniendoademás propiedades funcionales debido a estoscompuestos bioactivos.El maíz morado además aporta cantidades importantes de almidón, cerca del 80%; un10% de azúcares los cuales le confieren un sabor dulce, un 11% de proteínas, 2% de minerales y vitaminas(complejo B y ácido ascórbico concentrados en el endospermo. Además del valor nutricional, el maíz moradotiene una composición rica en fitoquímicos, que tienen efectos benéficos en nuestro cuerpo, tales comoneutralizar los radicales libres y actuar como antimutagénico.Este trabajo de revisión tuvo como objetivo,recopilar información sobre los estudios realizados al maíz morado,como alternativa al uso decolorantesartificiales de alimentos ypor susbeneficios a la salud al incluirlo en la dieta, tales como, enfermedadescardiovasculares (hipertensión arterial, reducción del colesterol, lucha contra la diabetes, siendo el másresaltante la acción antioxidante (antiarrugas.

Measurements of the Deuteron Elastic Structure Function A(Q2 ) for 0.7 ≤ Q2 ≤ 6.0 (GeV/c) 2 at Jefferson Laboratory

International Nuclear Information System (INIS)

Berthot, J.; Bertin, P.Y.; Breton, V.; Deur, A.; Fonvieille, H.; Jaminion, S.; Jutier, C.; Lavessiere, G.; Ravel, O.; Roblin, Y.; Aniol, K.A.; Epstein, M.B.; Margaziotis, D.J.; Howell, C.; Boeglin, W.U.; Kramer, L.H.; Markowitz, P.; Sarty, A.J.; Degrande, N.; Van Hoorebeke, L.; Baker, F.T.; Templon, J.A.; Mougey, J.Y.; Gasparian, A.; Madey, R.; Wilson, R.; De Leo, R.; Leone, A.; Perrino, R.; Cisbani, E.; Frullani, S.; Garibaldi, F.; Iodice, M.; Urciuoli, G.M.; Anderson, B.D.; Katramatou, A.T.; Khayat, M.; Madey, R.; Manley, D.M.; Petratos, G.G.; Prout, D.L.; Suleiman, R.; Watson, J.W.; Zhang, W.; Dale, D.S.; Gasparian, A.; Glamazdin, A.; Gorbenko, V.; Pomatsalyuk, R.; Sorokin, P.; Breuer, H.; Chang, C.; Ewell, L.A.; Kelly, J.J.; Bertozzi, W.; Fissum, K.G.; Gao, H.; Gao, J.; Gilad, S.; Liyanage, N.; Rowntree, D.; Zhao, J.; Zhou, Z.

1999-01-01

The deuteron elastic structure function A(Q 2 ) has been extracted in the range 0.7≤Q 2 ≤6.0 (GeV /c) 2 from cross section measurements of elastic electron-deuteron scattering in coincidence using the Hall A Facility of Jefferson Laboratory. The data are compared to theoretical models, based on the impulse approximation with the inclusion of meson-exchange currents, and to predictions of quark dimensional scaling and perturbative quantum chromodynamics. copyright 1999 The American Physical Society

Cold Gas in Quenched Dwarf Galaxies using HI-MaNGA

Science.gov (United States)

Bonilla, Alaina

2017-01-01

MaNGA (Mapping of Nearby Galaxies at Apache Point Observatory) is a 6-year Sloan Digital Sky Survey fourth generation (SDSS-IV) project that will obtain integral field spectroscopy of a catalogue of 10,000 nearby galaxies. In this study, we explore the properties of the passive dwarf galaxy sample presented in Penny et al. 2016, making use of MaNGA IFU (Integral Field Unit) data to plot gas emission, stellar velocity, and flux maps. In addition, HI-MaNGA, a legacy radio-survey of MaNGA, collects single dish HI data retrieved from the GBT (Green Bank Telescope), which we use to study the the 21cm emission lines present in HI detections. Studying the HI content of passive dwarves will help us reveal the processes that are preventing star formation, such as possible AGN feedback. This work was supported by the SDSS Research Experience for Undergraduates program, which is funded by a grant from the Sloan Foundation to the Astrophysical Research Consortium.

Ma2 antibodies: an evaluation of commercially available detection methods.

Science.gov (United States)

Johannis, Wibke; Renno, Joerg H; Wielckens, Klaus; Voltz, Raymond

2011-01-01

Ma2 antibodies belong to the onconeuronal antibodies which define a "definite" paraneoplastic neurological syndrome (PNS). Because of the clinical relevance, use of two separate methods (indirect immunofluorescence technique--IFT--and immunoblot) is advocated; however, with an increasing number of commercially available assay systems, usually only one assay is performed. We compared IFT and three commercially available immunoblots (ravo Diagnostika, Euroimmun, Milenia Biotec) on sera from 35 patients with clinically suspected PNS. 17 were Ma2 antibody associated as defined by consensus result (showing positive reactivity in 2 assays), 18 were Ma2 antibody negative controls. Sensitivity/specificity for single assays were for IFT 94%/94%, for ravo Diagnostika PNS blot 88%/100%, for Euroimmun Neuronal Antigens Profile blot 100%/89%, and for Milenia Biotec MTR blot 94%/100%. Our data confirm, although all tests performed well, a combination of 2 independent assays is still advisable for Ma2 antibody detection in order to achieve higher sensitivity and specificity rates.

Long pulse operation of high performance plasmas in JT-60U

International Nuclear Information System (INIS)

Ide, Shunsuke

2005-01-01

Recent experimental progress in JT-60U advanced tokamak research is presented; sustainment of the normalized beta (β N ) - 3 in a normal magnetic shear plasma, the bootstrap current fraction (f BS ) - 45% in a weak shear plasma and ∼75% in a reversed magnetic shear plasma in a nearly full non-inductive current drive condition for longer than the current relaxation time. Achievement of high-density high-radiation fraction together with high-confinement in advanced plasmas was demonstrated. Achievement and foundings in long pulse operations after system modification are presented as well. A 65 s discharge of I p =0.7 MA was successfully obtained. As a result, high-β N of 2.3 was successfully sustained for a very long period of 22.3 s. In addition, a 30 s standard ELMy H-mode plasma of I p up to 1.4 MA has also been obtained. Effectiveness of divertor pumping to control particle recycling and the electron density under the wall retention was saturated was demonstrated. These achievement and issues in the development will be discussed. (author)

National comparison of activity measurements of 131I, 60Co, and 133Ba in Indonesia

International Nuclear Information System (INIS)

Wurdiyanto, Gatot; Marsoem, Pujadi; Widodo, Susilo; Iskandar, Dadong; Muhayatun; Hartoyo, Unggul; Sugino; Gede Sutresna, I.; Hutabarat, Tommy; Suparman, Ibon; Purwanto, Setyo

2014-01-01

National comparisons of radioactivity measurements of 131 I and 60 Co (in 2010) and of 133 Ba (in 2011) were carried out within the framework of the National Radiation Metrology Laboratory Program of Indonesia, coordinated by PTKMR-BATAN. Eleven laboratories took part in the comparison, and all measurements were made using gamma spectrometry, on point sources with an activity between 2000 Bq and 6000 Bq. Several laboratories reported values which were more than 10% different from the reference value for 131 I and 133 Ba. Possible reasons for these differences are discussed. This program will be continued with other radionuclides to maintain and control quality assurance for the local laboratories. - Highlights: • PTKMR-BATAN coordinated national comparison of 131 I, 60 Co and 133 Ba. • Eleven laboratories took part in the comparison. • All measurements were done using gamma spectrometry methods. • For 131 I and 133 Ba, 3 laboratories have more than 10% difference from reference laboratory value

A 60 keV implanter for metals

International Nuclear Information System (INIS)

Leutenecker, R.; Ryssel, H.; Zeller, K.-H.; Spoehrle, H.P.

1985-01-01

The design and preliminary performance data of a 60 keV high current implanter for the implantation of non-separated ion beams into metals are described. The target chamber accepts samples up to 70 cm in diameter and is equipped with holders to implant ball bearings, axles and other components which have to be rotated during implantation. Samples are mounted on a rugged table which can move up to 35 kg for +-35 cm in the x and y directions. The implanter, including the vacuum system, is completely computer controlled. The ion source is equipped with an oven having a maximum temperature of 1200 0 C and can deliver ion beams of nitrogen as well as different metal ions such as tin and silver with currents up to 10 mA. (Auth.)

Patent Analysis for Supporting Merger and Acquisition (M&A) Prediction: A Data Mining Approach

Science.gov (United States)

Wei, Chih-Ping; Jiang, Yu-Syun; Yang, Chin-Sheng

M&A plays an increasingly important role in the contemporary business environment. Companies usually conduct M&A to pursue complementarity from other companies for preserving and/or extending their competitive advantages. For the given bidder company, a critical first step to the success of M&A activities is the appropriate selection of target companies. However, existing studies on M&A prediction incur several limitations, such as the exclusion of technological variables in M&A prediction models and the omission of the profile of the respective bidder company and its compatibility with candidate target companies. In response to these limitations, we propose an M&A prediction technique which not only encompasses technological variables derived from patent analysis as prediction indictors but also takes into account the profiles of both bidder and candidate target companies when building an M&A prediction model. We collect a set of real-world M&A cases to evaluate the proposed technique. The evaluation results are encouraging and will serve as a basis for future studies.

Safety in laboratories: Indian scenario.

Science.gov (United States)

Mustafa, Ajaz; Farooq, A Jan; Qadri, Gj; S A, Tabish

2008-07-01

Health and safety in clinical laboratories is becoming an increasingly important subject as a result of emergence of highly infectious diseases such as Hepatitis and HIV. A cross sectional study was carried out to study the safety measures being adopted in clinical laboratories of India. Heads of laboratories of teaching hospitals of India were subjected to a standardized, pretested questionnaire. Response rate was 44.8%. only 60% of laboratories had person in-charge of safety in laboratory. Seventy three percent of laboratories had safety education program regarding hazards. In 91% of laboratories staff is using protective clothing while working in laboratories. Hazardous material regulations are followed in 78% of laboratories. Regular health check ups are carried among laboratory staff in 43.4% of laboratories.Safety manual is available in 56.5% of laboratories. 73.9% of laboratories are equipped with fire extinguishers. Fume cupboards are provided in 34.7% of laboratories and they are regularly checked in 87.5% of these laboratories. In 78.26% of laboratories suitable measures are taken to minimize formation of aerosols.In 95.6% of laboratories waste is disposed off as per bio-medical waste management handling rules. Laboratory of one private medical college was accredited with NABL and safety parameters were better in that laboratory. Installing safety engineered devices apparently contributes to significant decrease in injuries in laboratories; laboratory safety has to be a part of overall quality assurance programme in hospitals. Accreditation has to be made necessary for all laboratories.

42 CFR 422.52 - Eligibility to elect an MA plan for special needs individuals.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Eligibility to elect an MA plan for special needs..., and Enrollment § 422.52 Eligibility to elect an MA plan for special needs individuals. (a) General rule. In order to elect a specialized MA plan for a special needs individual (Special Needs MA plan, or...

La evolución del mejoramiento del maíz

OpenAIRE

Arriaga, Héctor O.

1987-01-01

La producción e importancia primordial del maíz como grano forrajero, hacen que se sindique al maíz como el cereal más representativo de los países desarrollados. Por su producción mundial, ocupa el 2° lugar, después del trigo, con 481 millones de toneladas, de las que el 64 % corresponde a los países desarrollados. Estos son, a su vez, los principales exportadores y consumidores por ser también los más importantes importadores, con un 71 % de las 68 millones de toneladas de maíz que se...

46 CFR 308.529 - Surety Bond B, Form MA-309.

Science.gov (United States)

2010-10-01

... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.529 Surety Bond B, Form MA-309. An Assured who elects to substitute a surety bond for a collateral deposit fund shall submit Form MA-309...

Information managing in 60Co container inspection system

International Nuclear Information System (INIS)

Wu Zhifang; Gu Bohua; Zhou Liye; An Jigang; Liu Yisi

1998-01-01

The design, maintenance and realization of information managing database in 60 Co container inspection system made by INET of Tsinghua University is introduced. The technique of Open Database Connectivity (ODBC) is adopted to develop a general format database including text and graphic information. The database application is developed with Visual C ++ 5.0 programming language to run in 32-bit Windows operation system. It conforms to Client/Server model and supports network communication. It works very well in the laboratory emulator of 60 Co container inspection system

Intercalibration of analytical methods on marine environmental samples. Results of MEDPOL-II exercise for the intercalibration of chlorinated hydrocarbon measurements on mussel homogenate (MA-M-2/OC)

International Nuclear Information System (INIS)

1986-10-01

Mussels have been considered as good indicators of chlorinated hydrocarbon pollution of the marine environment and this led to the development of mussel watch programmes in many countries in the late seventies. These intercalibration exercises were arranged in order to increase the quality of analytical capabilities of environmental laboratories. The samples MA-M-2/0C of Mediterranean mussels with chlorinated hydrocarbon content were checked by 27 laboratories. It was judged highly suitable for these laboratories to have at their disposal a reference material made of mussel tissue with robust estimations of the true values with respect to several chlorinated hydrocarbons. Such a material would allow chemists to check the validity of new analytical procedures

Salatoimikud : ma tahan uskuda / Mart Rummo

Index Scriptorium Estoniae

Rummo, Mart

2008-01-01

USA sarjale "The X-Files" põhinev teine järjefilm "Salatoimikud: Ma tahan uskuda" ("The X-Files: I Want to Believe") : režissöör Chris Carter : peaosades David Duchovny, Gillian Anderson : Ameerika Ühendriigid - Kanada 2008

Role of low order rational q values in the ITB-events in JT-60U plasmas

International Nuclear Information System (INIS)

Neudatchin, S.V.

2002-01-01

The formation of internal transport barriers (ITBs) near q=2,3 surfaces in normal (NrS) or optimized shear discharges of JT-60U and JET is well known. In reverse shear (RS) JT-60U plasmas, the role of q minimum (q min ) equal to 3.5, 3, 2.5, 2 is not obvious for ITB evolution. ITB-events (non-local confinement bifurcations inside and around ITB in a ms timescale) are found in various JT-60U NrS and RS plasmas. (a) Under sufficient power, ITB-events are seen at rational and not rational values of q min . The space-time evolution of Te and Ti is similar. The temporal creation of stronger ITB in H-mode (after periodical improvements and degradations via ITB-events with 8 ms period) under passing of q min = 3 is presented (P nbi = 8 MW, 1.5 MA / 3.7 T). (b) Under smaller power, the influence of some rational q min is seen clearly for ITB-events on T e . In 1.3MA/3.7T shot with very weak RS (Pnbi = 4 MW), abrupt rise of T e is seen at q min 3:5, while more cases of T i rise are observed. (c) The possible role of MHD-activity as ITB-events trigger (ms time scale correlation in some NrS and RS cases) is under investigation. (author)

MaMiCo: Software design for parallel molecular-continuum flow simulations

KAUST Repository

Neumann, Philipp; Flohr, Hanno; Arora, Rahul; Jarmatz, Piet; Tchipev, Nikola; Bungartz, Hans-Joachim

2015-01-01

The macro-micro-coupling tool (MaMiCo) was developed to ease the development of and modularize molecular-continuum simulations, retaining sequential and parallel performance. We demonstrate the functionality and performance of MaMiCo by coupling

Design study of an AC power supply system in JT-60SA

International Nuclear Information System (INIS)

Shimada, Katsuhiro; Baulaigue, Olivier; Cara, Philippe; Coletti, Alberto; Coletti, Roberto; Matsukawa, Makoto; Terakado, Tsunehisa; Yamauchi, Kunihito

2011-01-01

In the initial research phase of JT-60SA, which is the International Thermonuclear Experimental Reactor (ITER) satellite Tokamak with superconducting toroidal and poloidal magnetic field coils, the plasma heating operation of 30 MW-60 s or 20 MW-100 s is planned for 5.5 MA single null divertor plasmas. To achieve this operation, AC power source of the medium voltage of 18 kV and ∼7 GJ has to be provided in total to the poloidal field coil power supplies and additional heating devices such as neutral beam injection (NBI) and electron cyclotron radio frequency (ECRF). In this paper, the proposed AC power supply system in JT-60SA was estimated from the view point of available power, and harmonic currents based on the standard plasma operation scenario during the initial research phase. This AC power supply system consists of the reused JT-60 power supply facilities including motor generators with flywheel, AC breakers, harmonic filters, etc., to make it cost effective. In addition, the conceptual design of the upgraded AC power supply system for the ultimate heating power of 41 MW-100 s in the extended research phase is also described.

Positive and Negative Impacts of Cross-border M&A

Institute of Scientific and Technical Information of China (English)

裴长洪; 林江

2007-01-01

Mergers and acquisitions of Chinese enterprises by foreign investors have moved onto the public radar in recent years.To date,the M&A frenzy has drawn widespread attention,with a mixed reaction from proponents and opponents.Proponents consider such mergers and acquisitions conducive to realizing strategic readjustment of the national economic structure,optimizing resource allocation and improving the corporate governance structure.Opponents,however,are concerned that foreign mergers and acquisitions may jeopardize China’s industrial security and erode the executive power of the central government in undertaking industrial development planning.Are the benefits of M&A outweighed by the costs,or vice versa? The focus column of this edition features two articles which debate this issue from opposing viewpoints.In the article"Positive and Negative Impacts of Cross-border M&A",the authors consider foreign M(?)A to be a new way of boosting the level of foreign investment utilization,and advocate China taking full advantage of this approach.The authors of the article"Self-Improvement Or Self-Mutilation",meanwhile,hold foreign M&A to blame for state-owned asset erosion,and insist that China should oppose mergers and acquisitions of key state- owned enterprises by foreign investors at fire-sale prices.

Secondary standard dosimetry laboratory at the Ruder Boskovic Institute, Zagreb, Croatia

International Nuclear Information System (INIS)

Vekic, B.; Ban, R.; Saveta, M.

2006-01-01

The Secondary Standard Dosimetry Laboratory at the Ruder Boskovic Institute, Zagreb, Croatia, was installed during the several last years. The installation of this Laboratory was strongly supported by the International Atomic Energy Agency (IAEA) through the Technical Cooperation Project (C.R.O. 1/004/; Establishing Calibration Services). Inside the country this Technical Cooperation Project was supported by the State Office for Standardization and Metrology, State Office for Radiation Protection and the Ministry of Health of the Republic of Croatia. The Secondary Standard Dosimetry Laboratory at the Ruder Boskovic Institute, Zagreb, Croatia was installed in two calibration rooms. The both of these calibration rooms are 9.6 meters long and 6 meters wide. In the both of these calibration rooms the proper air conditioning was installed. The walls of the both calibration rooms are thick enough (1 meter of concrete) and the entrance doors are protected by Pb to protect any radiation hazard in control rooms, in neighbouring rooms and in environment. In the first calibration room, placed in the basement, two sealed sources share the same calibration bench (produced by Hopewell Designs, Inc., USA) between them which is 6 meters long. On one side is Co -60 source of the 30 TBq activity (December 2004) for the calibration of radiotherapy ionizing chambers and the other equipment in the field of high dose rate range. On the other side is irradiation unit consists of 2 sealed sources for radiation protection purposes: (1) Cs-137 source, activity of 740 MBq (February 2004) and (2) Co- 60 source, activity of 185 MBq (February 2004). For this second source three attenuators are provided that give a nominal attenuation of *10, *100 and *1000. In the second calibration room placed just above the first one the X -ray unit (gift from P.T.B., Germany, I.S.O.V.O.L.T. 420, 40 -300 kV, 1-20 mA) is placed. In front of this are: (1.) Aperture Wheel Assembly designed to modify the beam

[The medical theory of Lee Je-ma and its character].

Science.gov (United States)

Lee, Kyung-Lock

2005-12-01

Lee Je-ma 1837-1900) was a prominent scholar as well as an Korean physician. classified every people into four distinctive types: greater yang [tai yang] person, lesser yin [shao yin] person, greater yin [tai yin] person, lesser yin [shao yin] person. This theory would dictate proper treatment for each type in accordance with individual differences of physical and temperament features. Using these four types he created The Medical Science of Four Types. This article is intended to look into the connection between Lee Je-Ma's 'The Medical Science of Four Types' and 'The Modern' with organizing his ideas about the human body and the human being. Through The Modern, the theory of human being underwent a complete change. Human being in The Premodern, which was determined by sex, age and social status has been changed to the individual human being, which is featured by equality. Lee Je-Ma's medical theory of The Medical Science of Four Types would be analyzed as follow. His concept of human body is oriented toward observable objectivity. But on the other hand, it still remains transcendent status of medical science, which is subordinated by philosophy. According to Lee Je-Ma's theory of human being, human is an equal individual in a modern way of thinking, not as a part of hierarchical group. But on the other hand, it still remains incomplete from getting rid of morality aspect that includes virtue and vice in the concept of human body. The common factors in Lee Je-Ma's ideas about the human body and the human being is 'Dualism of mind and body that means all kinds of status and results depends on each individual. As is stated above, Lee Je-Ma's medical theory has many aspects of The Modern and it proves that Korean traditional medicine could be modernized by itself.

An ECVAG inter-laboratory validation study of the comet assay

DEFF Research Database (Denmark)

Ersson, Clara; Møller, Peter; Forchhammer, Lykke

2013-01-01

of ionising radiation, inter-laboratory variation, intra-laboratory variation and residual variation contributed to 60.9, 19.4, 0.1 and 19.5%, respectively, of the total variation. In the coded PBMC samples, the inter-laboratory variation explained the largest fraction of the overall variation of DNA strand...

Technical Training: Annonce de nouveau cours: Utilisation des fichiers PDF avec ACROBAT 6.0

CERN Multimedia

Monique Duval

2005-01-01

CERN Technical Training 2005: Learning for the LHC! Un nouveau cours pratique sur Adobe Acrobat version 6.0 est proposé à l'ensemble du personnel par le service de l'Enseignement Technique, pour répondre aux besoins de formation des utilisateurs des documents PDF. La première session aura lieu le 1er mars 2005. Objectifs : Maîtriser les différentes fonctions d'Adobe Acrobat 6.0. Programme : Présentation d'Adobe Acrobat 6.0. Création de fichiers PDF depuis Microsoft Office et d'autres applications. Création de fichiers Postscript. Modification de fichiers PDF, enregistrement et exportation. Protection par mot de passe et par signature numérique. Navigation dans les documents : interactivité, vignettes et pages, signets, liens, articles, affichage et ouverture des PDF, recherche. Travail en commun: Ajout de commentaires, révision par messagerie électronique Dur&e...

MaNGA: Mapping Nearby Galaxies at Apache Point Observatory

Science.gov (United States)

Weijmans, A.-M.; MaNGA Team

2016-10-01

MaNGA (Mapping Nearby Galaxies at APO) is a galaxy integral-field spectroscopic survey within the fourth generation Sloan Digital Sky Survey (SDSS-IV). It will be mapping the composition and kinematics of gas and stars in 10,000 nearby galaxies, using 17 differently sized fiber bundles. MaNGA's goal is to provide new insights in galaxy formation and evolution, and to deliver a local benchmark for current and future high-redshift studies.

Technical committee on reactor physics of next generation. Examination of MA recycling by using PWRs

International Nuclear Information System (INIS)

Mori, Masaaki

1995-01-01

It is an important subject to be examined that during the period till full scale nuclear fuel recycling including the adoption of FBRs will be realized, we never have excess Pu. As the realistic examination considering the nuclear fuel recycling for the time being, the MOX fuel for PWRs of actinide recycling, ultralong life, placing emphasis on the concentrated charging of Pu and the confinement of MA in nuclear fuel cycling was examined. The change of the infinite multiplication rate of actinide recycling fuel is small throughout the burning, and there is the possibility of attaining the high burnup about twice of that of UO 2 fuel. The merit of the case of adding MA in small amount by recycling MA together with Pu at the proportion in spent fuel is shown. The amount of MA accumulation in Japan until 2050 was evaluated by the survey of the electric power generation of every reactor type using the long term reactor type strategy evaluation code LSER. By comparing the amount of MA accumulation in four MA recycling cases with the basic case without MA recycling, the amount of MA annihilation was evaluated. It was found that the MA recycling using PWRs only is not inferior to the multi-recycling of MA using FBRs. (K.I.)

Formation of buckminsterfullerene (C60) in interstellar space

Science.gov (United States)

Berné, Olivier; Tielens, Alexander G. G. M.

2012-01-01

Buckminsterfullerene (C60) was recently confirmed to be the largest molecule identified in space. However, it remains unclear how, and where this molecule is formed. It is generally believed that C60 is formed from the build up of small carbonaceous compounds, in the hot and dense envelopes of evolved stars. Analyzing infrared observations, obtained by Spitzer and Herschel, we found that C60 is efficiently formed in the tenuous and cold environment of an interstellar cloud illuminated by strong ultraviolet (UV) radiation fields. This implies that another formation pathway, efficient at low densities, must exist. Based on recent laboratory and theoretical studies, we argue that Polycyclic Aromatic Hydrocarbons are converted into graphene, and subsequently C60, under UV irradiation from massive stars. This shows that alternative - top-down - routes are key to understanding the organic inventory in space.

Moon/Mars Landing Commemorative Release: Gusev Crater and Ma'adim Vallis

Science.gov (United States)

1998-01-01

the mouth of Ma'adim Vallis--are composed of sediment that eroded out of the highlands to the south of Gusev Crater. In 1995, the Exobiology Program Office at NASA Headquarters produced a report, An Exobiological Strategy for Mars Exploration (NASA SP-530), that included Gusev Crater as a possible priority site for future Mars exploration because it might once have been a lake.At 12:17 a.m. (PDT) on April 24, 1998-- during Mars Global Surveyor's 259th orbit--MOC obtained the high resolution image of Gusev Crater and Ma'adim Vallis shown above, in part to test some of the proposed hypotheses. The raw image has a scale of 7.3 meters (24 feet) per pixel. At this scale, there are no obvious shorelines that would indicate the past presence of a lake in either Ma'adim Vallis or Gusev Crater. There are several alternative explanations for this absence, including: It is possible that any lake in Gusev occurred so long ago that erosion by wind and hillslope processes have long since removed such features. It is possible that 7.3 meters per pixel is insufficient to identify key diagnostic lake features. It is possible that a lake once existed, but that shore- and near-shore processes as they occur in terrestrial lake environments did not occur on Mars. It is possible no lake ever existed. When Mars Global Surveyor achieves its Mapping Orbit in March 1999, MOC will have the ability to obtain pictures with resolutions around 1.5 meters (5 feet) per pixel. Sometime during the mapping mission, it may be possible to image Gusev Crater again to look for potential lake features and possible future landing sites.Malin Space Science Systems and the California Institute of Technology built the MOC using spare hardware from the Mars Observer mission. MSSS operates the camera from its facilities in San Diego, CA. The Jet Propulsion Laboratory's Mars Surveyor Operations Project operates the Mars Global Surveyor spacecraft with its industrial partner, Lockheed Martin Astronautics, from

How to use MAED with other IAEA models in ENPEP

International Nuclear Information System (INIS)

Maksijan, B.

1997-01-01

This paper provides an outlook of the energy situation in Croatia and describes the experience with the IAEA planning methodologies with focus on the MAED model. Furthermore, it suggests an approach to integrate the results of the MAED module of ENPEP with other modules (e.g. BALANCE) by means of commercial software (EXCEL Microsoft). (author). 2 figs, 3 tabs

How to use MAED with other IAEA models in ENPEP

Energy Technology Data Exchange (ETDEWEB)

Maksijan, B [Energy Sector, Ministry of Economic Affairs, Zagreb (Croatia)

1997-09-01

This paper provides an outlook of the energy situation in Croatia and describes the experience with the IAEA planning methodologies with focus on the MAED model. Furthermore, it suggests an approach to integrate the results of the MAED module of ENPEP with other modules (e.g. BALANCE) by means of commercial software (EXCEL Microsoft). (author). 2 figs, 3 tabs.

MaMBA - a functional Moon and Mars Base Analog

Science.gov (United States)

Heinicke, C.; Foing, B.

2017-09-01

Despite impressive progress in robotic exploration of celestial bodies, robots are believed to never reach the effectiveness and efficiency of a trained human. Consequently, ESA proposes to build an international Moon Village in roughly 15 years and NASA plans for the first manned mission to Mars shortly after. One of the challenges still remaining is the need for a shelter, a habitat which allows human spacefarers to safely live and work on the surface of a celestial body. Although a number of prototype habitats has been built during the last decades and inhabited for various durations (e.g. MDRS, FMARS, HI-SEAS, M.A.R.S.), these habitats are typically equipped for studies on human factors and would not function in an extraterrestrial environment. Project MaMBA (Moon and Mars Base Analog) aims to build the first functional habitat based on the lessons learned from intermediate and long duration missions at the mentioned habitats. The habitat will serve for testing technologies like life support, power systems, and interplanetary communi­cation. Special attention will be given to the develop­ment of the geoscience laboratory module. Crews will live and work inside the habitat to ensure its functionality.

MaGnET: Malaria Genome Exploration Tool.

Science.gov (United States)

Sharman, Joanna L; Gerloff, Dietlind L

2013-09-15

The Malaria Genome Exploration Tool (MaGnET) is a software tool enabling intuitive 'exploration-style' visualization of functional genomics data relating to the malaria parasite, Plasmodium falciparum. MaGnET provides innovative integrated graphic displays for different datasets, including genomic location of genes, mRNA expression data, protein-protein interactions and more. Any selection of genes to explore made by the user is easily carried over between the different viewers for different datasets, and can be changed interactively at any point (without returning to a search). Free online use (Java Web Start) or download (Java application archive and MySQL database; requires local MySQL installation) at http://malariagenomeexplorer.org joanna.sharman@ed.ac.uk or dgerloff@ffame.org Supplementary data are available at Bioinformatics online.

Implementation of a quality management system at the PHOENIX facility (CryoMaK)

International Nuclear Information System (INIS)

Urbach, Elisabeth; Bagrets, Nadezda; Weiss, Klaus-Peter

2013-01-01

Within a variety of mechanical tests in the Cryogenic Material Test Facility Karlsruhe (CryoMaK) at Karlsruhe Institute of Technology (KIT) the PHOENIX facility was prepared for multiple standard tensile tests in liquid helium, liquid nitrogen and at room temperature. With the multiple specimens holder 10 specimens can be tested within one cool down one after another. A quality management system is needed for ensuring reproducible preconditions. For the guarantee of the competence of the laboratory and the measurement equipment, a quality management system was implemented and prepared for accreditation according to DIN EN ISO/IEC 17025 (ISO 17025). The implementation of a quality management system allows high precision test results included the estimation of measurement uncertainty. This paper gives an overview of the management and technical requirements for the accreditation of the PHOENIX testing facility

Implementation of a quality management system at the PHOENIX facility (CryoMaK)

Energy Technology Data Exchange (ETDEWEB)

Urbach, Elisabeth, E-mail: elisabeth.urbach@kit.edu; Bagrets, Nadezda; Weiss, Klaus-Peter

2013-10-15

Within a variety of mechanical tests in the Cryogenic Material Test Facility Karlsruhe (CryoMaK) at Karlsruhe Institute of Technology (KIT) the PHOENIX facility was prepared for multiple standard tensile tests in liquid helium, liquid nitrogen and at room temperature. With the multiple specimens holder 10 specimens can be tested within one cool down one after another. A quality management system is needed for ensuring reproducible preconditions. For the guarantee of the competence of the laboratory and the measurement equipment, a quality management system was implemented and prepared for accreditation according to DIN EN ISO/IEC 17025 (ISO 17025). The implementation of a quality management system allows high precision test results included the estimation of measurement uncertainty. This paper gives an overview of the management and technical requirements for the accreditation of the PHOENIX testing facility.

The design study of the JT-60SU device. No. 3. The superconductor-coils of JT-60SU

International Nuclear Information System (INIS)

Ushigusa, Kenkichi; Mori, Katsuharu; Nakagawa, Syouji

1997-03-01

The superconducting coil systems and the cryogenic system for the JT-60 Super Upgrade (JT-60SU) has been designed. Both Nb 3 Al and NbTi as a superconducting wire material are employed in the toroidal coils (D-shaped 18 coils) to realize a high field magnet with a low cost. Significant reduction of the coil weight (150 tons/coil) without losing the coil rigidity has been achieved by connecting two toroidal coils with shear panels. Validity of this design is confirmed by the detailed structural analysis and thermohydraulic analysis. The poloidal coil system consists of 4 central solenoid coils with (NbTi) 3 Sn and 6 outer equilibrium field coils with NbTi. This system has an enough capability to supply the flux of 170Vs to produce a 10MA discharge with 200s of flat-top and to make various plasma configurations. The construction procedure of the poloidal coil system is also established under the constraint of the JT-60 site. Two sets of race-track shaped superconducting coils mounted on the top of the machine is designed to compensate the error field inside the vessel by supplying helical (m=2/n=1) magnetic field. By using cryogenic system with a 36kW of cooling capacity, the total cold weight of around 4000tons can be cooled down to 4.5K within one month, and steady heat load of 6.5kW and transient heat load of 9.0MJ can be removed within 30 minutes of discharge repetition rate. (author)

[How do hospital clinical laboratories and laboratory testing companies cooperate and build reciprocal relations?].

Science.gov (United States)

Kawano, Seiji

2014-12-01

As the 2nd Joint Symposium of the Japanese Society of Laboratory Medicine and the Japanese Association of Laboratory Pathologists, the symposium on clinical test out-sourcing and branch laboratories was held at the 60th General Meeting of the Japanese Society of Laboratory Medicine on November 2nd, 2013 in Kobe. For the symposium, we conducted a questionnaire survey on the usage of clinical test out-sourcing and the introduction of branch laboratories to clinical laboratories of Japanese university hospitals, both private and public, between July 25th and August 20th, 2013. Seventy-two hospitals responded to the questionnaire survey, consisting of 41 public medical school hospitals and 31 private ones. According to the survey, the selection of each clinical test for out-sourcing was mainly determined by the capacities of hospital clinical laboratories and their equipment, as well as the profitability of each test. The main concerns of clinical laboratory members of university hospitals involved the continuity of measurement principles, traceability, and standardization of reference values for each test. They strongly requested the interchangeability and computerization of test data between laboratory testing companies. A branch laboratory was introduced to six hospitals, all of which were private medical college hospitals, out of 72 university hospitals, and eight of the other hospitals were open to its introduction. The merits and demerits of introducing a branch laboratory were also discussed. (Review).

New Regimes of Implosions of Larger Sized Wire Arrays With and Without Modified Central Plane at 1.5-1.7 MA Zebra

Science.gov (United States)

Safronova, A. S.; Kantsyrev, V. L.; Esaulov, A. A.; Weller, M. E.; Shrestha, I.; Shlyaptseva, V. V.; Stafford, A.; Keim, S. F.; Petkov, E. E.; Lorance, M.; Chuvatin, A. S.; Coverdale, C. A.; Jones, B.

2013-10-01

The recent experiments at 1.5-1.7 MA on Zebra at UNR with larger sized planar wires arrays (compared to the wire loads at 1 MA current) have demonstrated higher linear radiation yield and electron temperatures as well as advantages of better diagnostics access to observable plasma regions. Such multi-planar wire arrays had two outer wire planes from mid-Z material to create a global magnetic field (gmf) and mid-Z plasma flow between them. Also, they included a modified central plane with a few Al wires at the edges to influence gmf and to create Al plasma flow in the perpendicular direction. The stationary shock waves which existed over tens of ns on shadow images and the early x-ray emissions before the PCD peak on time-gated spectra were observed. The most recent experiments with similar loads but without the central wires demonstrated a very different regime of implosion with asymmetrical jets and no precursor formation. This work was supported by NNSA under DOE Cooperative Agreement DE-NA0001984 and in part by DE-FC52-06NA27616. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Company, for the U.S. Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL85000.

Anti-Ma2-associated encephalitis with normal FDG-PET: a case of pseudo-Whipple's disease.

Science.gov (United States)

Castle, James; Sakonju, Ai; Dalmau, Josep; Newman-Toker, David E

2006-10-01

A 39-year-old man presented with a history of several months of progressive personality changes, social withdrawal, bradykinesia, mutism, dysphagia, worsening gait, and difficulty with daily living activities. Examination revealed an atypical parkinsonian appearance with incomplete supranuclear ophthalmoplegia and an unusual oculomotor disorder characterized by both low-amplitude, intermittent opsoclonus, and slow, nystagmoid intrusions. Routine laboratory testing, autoimmune and infectious serologies, brain MRI, lumbar puncture, electroencephalogram, whole-body CT scan, paraneoplastic serologies, small bowel biopsy, 18F-fluorodeoxyglucose positron emission tomography CT scan, brain biopsy, and testicular ultrasound. Anti-Ma2 paraneoplastic encephalitis in association with metastatic testicular cancer; initially misdiagnosed as CNS Whipple's disease. Corticosteroids, intravenous immunoglobulins, orchiectomy, muscle relaxants, mycophenolate mofetil, plasmapheresis, and bleomycin, etoposide and platinum chemotherapy.

Total Absorption Spectroscopy Study of the Beta Decay of 60Mn to Constrain the Neutron Capture Rate of 60Fe

Science.gov (United States)

Richman, Debra; Spyrou, Artemis; Dombos, Alex; Couture, Aaron; e15034 Collaboration

2017-09-01

Interest in 60Fe, a long lived radioisotope synthesized in massive stars, has recently peaked. The signature of its decay allows us to probe astrophysical processes, events such as the early formation of the solar system and nucleosynthesis. To understand these observations a complete understanding of the creation, destruction and nuclear properties of 60Fe in the astrophysical environment are required. Using the beta decay of 60Mn in conjunction with total absorption spectroscopy (TAS), made possible by the high efficiency gamma ray calorimeter SuN (Summing NaI detector) at the National Superconducting Cyclotron Laboratory (NSCL), to study the distribution of beta-decay intensity over the daughter-nucleus 60Fe, provides information about the structure of the daughter and improves the predictive power of astrophysical models. In addition to the ongoing TAS analysis, The Beta-Oslo method will be used to extract the nuclear level density and gamma-strength function of 60Fe providing much needed constraints on the neutron capture reaction rate responsible for the creation of this nucleus.

Açúcar mascavo em geleiadas de maçã Brown sugar in apple jellies

Directory of Open Access Journals (Sweden)

Carla Rosane Mendonça

2000-12-01

Full Text Available O trabalho objetivou elaborar geleiadas de maçã utilizando açúcar mascavo. As geleiadas foram elaboradas com polpa de maçã, água, suco de limão, pectina e 20, 35, 50 e 65% de açúcar mascavo em relação à quantidade de polpa. Verificou-se o rendimento, custo, e a preferência do consumidor pelas diferentes formulações. As geleiadas mais preferidas foram reelaboradas e determinaram-se as características físicas, químicas e microbiológicas, logo após o processamento, aos 30, 60 e 90 dias de estocagem. Os resultados permitiram concluir que as geleiadas elaboradas com 35, 50 e 65% de açúcar mascavo foram igualmente preferidas pelos consumidores, superando aquela com 20%; considerando o custo e o rendimento, verificou-se que a geleiada com 65% de açúcar mascavo apresentou vantagem sobre as demais; a estabilidade desses produtos foi superior a três meses; e existiram diferenças físicas e químicas significativas entre as formulações.The work had the objective to elaborate apple jellies by using brown sugar. The jellies were elaborated with apple pulp, water, lemon juice, pectin and 20, 35, 50 and 65% of brown sugar. It was verified the yield, cost and the consumer's preference of the jelly formulations. The most favorite jellies, were reprocessed, and it was determined the physical, chemical and microbiological characteristics, soon after the processing, after 30, 60 and 90 days of storage. It was observed that the jellies elaborated with 35, 50 and 65% of brown sugar were equally acceptable by the consumers, overcoming that ones with 20%; the jelly with 65% of brown sugar presented advantages over the others, when considering the cost and yield; the products stability was superior to three months and there were a physical and chemical significative difference among the formulations.

Sandia National Laboratories: About Sandia: History

Science.gov (United States)

Environmental Management System Pollution Prevention History 60 impacts Diversity Locations Facts & Figures Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers

Charge resolution of a Hungarian brand CR-39(MA-ND) detector exposed to a 84Kr beam of energy 0.45A GeV

International Nuclear Information System (INIS)

Bhattacharyya, D.P.; Basu, B.; Pal, P.; Mukherjee, S.C.; Ganguly, A.K.; Hunyady, I.

1990-01-01

The Hungarian brand CR-39(MA-ND) plastic has been irradiated with a 84 Kr ion beam of energy 0.45A GeV and etched for four different etching times, viz. 4, 6, 8 and 12 h. The estimated charge resolution of a CR-39(MA-ND) detector for registering the nuclei 32 ≤ Z ≤ 36 was found to be 0.18e which is close to our previous observation of the response with a CR-39(DOP) Pershore made plate exposed to a 1.88A GeV 56 Fe beam at the Lawrence Berkeley Laboratory's Bevalac. It was found that the estimated etch rate ratio V T /V G is independent of etching time. The cone length and minor axis of the etch pits has been found to increase with etching time. (orig.)

Anti-ma2 paraneoplastic encephalitis in association with recurrent cervical cancer.

Science.gov (United States)

Ney, Douglas E; Messersmith, Wells; Behbakht, Kian

2014-07-01

Paraneoplastic neurological syndromes are rare, and although they are frequently associated with gynecological malignancies, cervical cancer is a rare cause. The symptoms of anti-Ma2 encephalitis are diverse and often present prior to the diagnosis of malignancy. We report a case of a 37-year-old woman with a history of cervical cancer presenting with unexplained weight gain and vertical supranuclear gaze palsy. Magnetic resonance imaging of the brain revealed lesions within the bilateral hypothalami and midbrain. Anti-Ma2 antibodies were eventually found in the serum, prompting a search for malignancy. Recurrent metastatic cervical cancer was found in the retroperitoneal lymph nodes. This is the first report of cervical cancer in association with anti-Ma2 encephalitis, and highlights the need for a high degree of suspicion in patients with a cancer history presenting with neurological symptoms. The symptoms associated with anti-Ma2 encephalitis are diverse and typically precede the diagnosis of cancer in patients, and should trigger a search for an underlying malignancy.

Intercalibration of analytical methods on marine environmental samples. Results of MEDPOL II exercise for the intercomparison of trace element measurements on mussel tissue homogenate and marine sediment (MA-M-2/TM and SD-N-1/2/TM)

International Nuclear Information System (INIS)

1986-12-01

Mussels and coastal sediments are often considered as pollution indicators of the marine environment. These intercalibration exercises were organised in order to check the analytical performances of environmental laboratories. The samples MA-M-2/TM of Mediterranean mussels and SD-N-1/2/TM of surface sediment from the Scheldt Estuary (North Sea) were analysed by 19 laboratories for determination of 15 elements: Ag, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Sb, Se, V and Zn. The analytical methods of atomic absorption spectroscopy, neutron activation analysis and voltametry were used in this intercomparison. For the mussel MA-M-2/TM, 65% of the reported coefficients of variation lie between 0 and 10%, 25% are between 10 and 20%, 9% between 20 and 30% and only 1% higher than 30%. In the case of the sediment SD-N-1/2/TM, 90% of the reported coefficients of variation lie between 0 and 10% and the remaining 10% are between 10 and 20%. The total number of outliers is moderate (9.2% of all results in the case of MA-M-2/TM and 3.0% in the case of SD-N-1/2/TM)

Spontaneous atopic dermatitis-like symptoms in a/a ma ft/ma ft/J flaky tail mice appear early after birth.

Directory of Open Access Journals (Sweden)

Magdalini Kypriotou

Full Text Available Loss-of-function mutations in human profilaggrin gene have been identified as the cause of ichthyosis vulgaris (IV, and as a major predisposition factor for atopic dermatitis (AD. Similarly, flaky tail (a/a ma ft/ma ft/J mice were described as a model for IV, and shown to be predisposed to eczema. The aim of this study was to correlate the flaky tail mouse phenotype with human IV and AD, in order to dissect early molecular events leading to atopic dermatitis in mice and men, suffering from filaggrin deficiency. Thus, 5-days old flaky tail pups were analyzed histologically, expression of cytokines was measured in skin and signaling pathways were investigated by protein analysis. Human biopsies of IV and AD patients were analyzed histologically and by real time PCR assays. Our data show acanthosis and hyperproliferation in flaky tail epidermis, associated with increased IL1β and thymic stromal lymphopoietin (TSLP expression, and Th2-polarization. Consequently, NFκB and Stat pathways were activated, and IL6 mRNA levels were increased. Further, quantitative analysis of late epidermal differentiation markers revealed increased Small proline-rich protein 2A (Sprr2a synthesis. Th2-polarization and Sprr2a increase may result from high TSLP expression, as shown after analysis of 5-days old K14-TSLP tg mouse skin biopsies. Our findings in the flaky tail mouse correlate with data obtained from patient biopsies of AD, but not IV. We propose that proinflammatory cytokines are responsible for acanthosis in flaky tail epidermis, and together with the Th2-derived cytokines lead to morphological changes. Accordingly, the a/a ma ft/ma ft/J mouse model can be used as an appropriate model to study early AD onset associated with profilaggrin deficiency.

Evaluation overview for the Massachusetts Childhood Obesity Research Demonstration (MA-CORD) project.

Science.gov (United States)

Davison, Kirsten K; Falbe, Jennifer; Taveras, Elsie M; Gortmaker, Steve; Kulldorff, Martin; Perkins, Meghan; Blaine, Rachel E; Franckle, Rebecca L; Ganter, Claudia; Baidal, Jennifer Woo; Kwass, Jo-Ann; Buszkiewicz, James; Smith, Lauren; Land, Thomas

2015-02-01

The Massachusetts Childhood Obesity Research Demonstration (MA-CORD) project is a 2-year, multilevel, multisector community intervention to prevent and control obesity among children 2-12 years of age from two predominantly low-income communities in Massachusetts. MA-CORD includes evidence-based interventions in multiple sectors, including community health centers, early care and education centers, schools, afterschool programs, the Special Supplemental Nutrition Program for Women, Infants and Children, and the broader community. Currently, implementation of MA-CORD is complete and the final year of data collection is in progress. Here, the MA-CORD evaluation plan is described and baseline data are presented. The impact of MA-CORD on children's BMI, lifestyle behaviors, obesity-related care, and quality of life will be assessed using sector-specific, pre/post, time-series, and quasi-experimental designs. Change in the primary outcomes will be compared for intervention and comparison communities. Additionally, change in mean BMI and obesity prevalence in intervention school districts will be compared to similar districts throughout the state. At baseline in 2012, approximately 16% of preschool-aged and 25% of school-aged children were obese. Moreover, 15-40% of children consumed no vegetables on the previous day, 25-75% drank a sugar-sweetened beverage on the previous day, up to 87% had insufficient physical activity, 50-75% had a television in the room where they slept, and 50-80% obtained insufficient sleep. There is ample room for improvement in BMI and health behaviors in children in MA-CORD communities. If successful, MA-CORD may serve as a model for multilevel, multisector approaches to childhood obesity prevention and control.

Development of ITER 15 MA ELMy H-mode Inductive Scenario

International Nuclear Information System (INIS)

C. E. Kessel, D. Campbell, Y. Gribov, G. Saibene, G. Ambrosino, T. Casper, M. Cavinato, H. Fujieda, R. Hawryluk, L. D. Horton, A. Kavin, R. Kharyrutdinov, F. Koechl, J. Leuer, A. Loarte, P. J. Lomas, T. Luce, V. Lukash, M. Mattei, I.Nunes, V. Parail, A. Polevoi, A. Portone, R. Sartori, A.C.C. Sips, P. R. Thomas, A. Welander and J. Wesley

2008-01-01

The poloidal field (PF) coil system on ITER, which provides both feedforward and feedback control of plasma position, shape, and current, is a critical element for achieving mission performance. Analysis of PF capabilities has focused on the 15 MA Q = 10 scenario with a 300-500 s flattop burn phase. The operating space available for the 15 MA ELMy H-mode plasma discharges in ITER and upgrades to the PF coils or associated systems to establish confidence that ITER mission objectives can be reached have been identified. Time dependent self-consistent free-boundary calculations were performed to examine the impact of plasma variability, discharge programming, and plasma disturbances. Based on these calculations a new reference scenario was developed based upon a large bore initial plasma, early divertor transition, low level heating in L-mode, and a late H-mode onset. Equilibrium analyses for this scenario indicate that the original PF coil limitations do not allow low li (<0.8) operation or lower flux states, and the flattop burn durations were predicted to be less than the desired 400 s. This finding motivates the expansion of the operating space, considering several upgrade options to the PF coils. Analysis was also carried out to examine the feedback current reserve required in the CS and PF coils during a series of disturbances and a feasibility assessment of the 17 MA scenario was undertaken. Results of the studies show that the new scenario and modified PF system will allow a wide range of 15 MA 300-500 s operation and more limited but finite 17 MA operation

Prevention and treatment of CCV in patients undergoing cataract phacoemulsification

Directory of Open Access Journals (Sweden)

E. Yu. Yazykova

2015-01-01

Full Text Available The study was hold on the basis of LLC «Eye Microsurgery» in Astrakhan.Purpose: clinical evaluation the influence of Systane Balance (Alcon the condition of the «ocular surface comfort» at patients with phaco.Materials and methods. 60 patients took part in the study. 30 men and 30 women aged from 68 to 80 years. After the first survey the patients were divided into two groups by means of random choice (15 men and 15 women in each group. Three days before the surgery Both groups of patients received antibiotics (Vigamox (Alcon and NSAIDs (Nevanac, Alcon according to the standard scheme for preoperative preparation (during 3 days before operation. These drugs were also recommended in the postoperative period. Systane Balance (1 drop 2‑3 times a day was prescribed for the first group in 2 weeks before phaco. The second group didn’t get any artificial tears. Systane Balance had been chosen as an artificial tears as its composition is very close to the natural tear film, compensates the deficiency of the lipid layer that is broken when meibomean gland dysfunction (MGD thus it prevents from increasing tear film osmolarity and its rupture.Results: In 60% (36 people SSG was due to dysfunction of the meibomian glands, and 40% (24 people had a different genesis (endocrine pathology, receiving β-blockers for local and systemic effects, long-term use of drugs containing the preservative benzalkonium chloride, menopause. One week after phacoemulsification all patients of group 1, treated with the drug Sisteyn Balance dramatically decreased the severity of complaints of dry eye, foreign body sensation, burning, lacrimation, blurred vision in comparison with the group without artificial tears One month after surgery, these complaints were even less pronounced. At the same time, subjective complaints in patients of the second group observed significantly more frequently than before surgery.Conclusions. The patients who belong to the

The medical theory of Lee Je-ma and its character

Directory of Open Access Journals (Sweden)

LEE Kyung-Lock

2005-12-01

Full Text Available Lee Je-ma(李濟馬, 1837-1900 was a prominent scholar as well as an Korean physician He classified every people into four distinctive types: greater yang[tai yang] person, lesser yin[shao yin] person greater yin[tai yin] person, lesser yin[shao yin] person. This theory would dictate proper treatment for each type in accordance with individual differences of physical and temperament features Using these four types he created The Medical Science of Four Types(四象體質論.This article is intended to look into the connection between Lee Je-Ma's 'The Medical Science of Four Types' and 'The Modern' with organizing his ideas about the human body and the human being. Through The Modern, the theory of human being(人間觀 underwent a complete change. Human being in The Premodern, which was determined by sex, age and social status has been changed to the individual human being, which is featured by equality. Lee Je-Ma's medical theory of The Medical Science of Four Types would be analyzed as follow. His concept of human body(人體論 is oriented toward observable objectivity. But on the other hand, it still remains transcendent status of medical science, which is subordinated by philosophy According to Lee Je-Ma's theory of human being human is an equal individual in a modern way of thinking not as a part of hierarchical group. But on the other hand, it still remains incomplete from getting rid of morality aspect that includes virtue and vice in the concept of human body.The common factors in Lee Je-Ma's ideas about the human body and the human being is 'Dualism of mind and body(心身二元論' that means all kinds of status and results depends on each individual. As is stated above, Lee Je-Ma's medical theory has many aspects of The Modern and it proves that Korean traditional medicine could be modernized by itself.

Design of an upgradeable 45-100 mA RFQ accelerator for FAIR

Science.gov (United States)

Zhang, Chuan; Schempp, Alwin

2009-10-01

A 325 MHz, 35 mA, 3 MeV Radio-Frequency Quadrupole (RFQ) accelerator will be operated as the first accelerating structure of the proton linac injector for the newly planned international science center Facility for Antiproton and Ion Research (FAIR) at GSI, Germany. In previous design studies, two high beam intensities, 70 and 100 mA, were used. Most recently, the design intensity has been changed to 45 mA, which is closer to the operational value. Taking advantage of the so-called New Four-Section Procedure, a new design, which is upgradable from 45 to 100 mA, has been developed for the FAIR proton RFQ. Besides the upgradability analyses, robustness studies of the new design to spatial displacements of the input beam and field errors are presented as well.

Design of an upgradeable 45-100 mA RFQ accelerator for FAIR

International Nuclear Information System (INIS)

Zhang Chuan; Schempp, Alwin

2009-01-01

A 325 MHz, 35 mA, 3 MeV Radio-Frequency Quadrupole (RFQ) accelerator will be operated as the first accelerating structure of the proton linac injector for the newly planned international science center Facility for Antiproton and Ion Research (FAIR) at GSI, Germany. In previous design studies, two high beam intensities, 70 and 100 mA, were used. Most recently, the design intensity has been changed to 45 mA, which is closer to the operational value. Taking advantage of the so-called New Four-Section Procedure, a new design, which is upgradable from 45 to 100 mA, has been developed for the FAIR proton RFQ. Besides the upgradability analyses, robustness studies of the new design to spatial displacements of the input beam and field errors are presented as well.

Recurrent Early Cretaceous, Indo-Madagascar (89-86 Ma) and Deccan (66 Ma) alkaline magmatism in the Sarnu-Dandali complex, Rajasthan: 40Ar/39Ar age evidence and geodynamic significance

Science.gov (United States)

Sheth, Hetu; Pande, Kanchan; Vijayan, Anjali; Sharma, Kamal Kant; Cucciniello, Ciro

2017-07-01

The Sarnu-Dandali alkaline complex in Rajasthan, northwestern India, is considered to represent early, pre-flood basalt magmatism in the Deccan Traps province, based on a single 40Ar/39Ar age of 68.57 Ma. Rhyolites found in the complex are considered to be 750 Ma Malani basement. Our new 40Ar/39Ar ages of 88.9-86.8 Ma (for syenites, nephelinite, phonolite and rhyolite) and 66.3 ± 0.4 Ma (2σ, melanephelinite) provide clear evidence that whereas the complex has Deccan-age (66 Ma) components, it is dominantly an older (by 20 million years) alkaline complex, with rhyolites included. Basalt is also known to underlie the Early Cretaceous Sarnu Sandstone. Sarnu-Dandali is thus a periodically rejuvenated alkaline igneous centre, active twice in the Late Cretaceous and also earlier. Many such centres with recurrent continental alkaline magmatism (sometimes over hundreds of millions of years) are known worldwide. The 88.9-86.8 Ma 40Ar/39Ar ages for Sarnu-Dandali rocks fully overlap with those for the Indo-Madagascar flood basalt province formed during continental breakup between India (plus Seychelles) and Madagascar. Recent 40Ar/39Ar work on the Mundwara alkaline complex in Rajasthan, 120 km southeast of Sarnu-Dandali, has also shown polychronous emplacement (over ≥ 45 million years), and 84-80 Ma ages obtained from Mundwara also arguably represent post-breakup stages of the Indo-Madagascar flood basalt volcanism. Remnants of the Indo-Madagascar province are known from several localities in southern India but hitherto unknown from northwestern India 2000 km away. Additional equivalents buried under the vast Deccan Traps are highly likely.

Establishment of nuclear data system - Feasibility study for neutron-beam= facility at pohang accelerator laboratory

Energy Technology Data Exchange (ETDEWEB)

Nam Kung, Won; Koh, In Soo; Cho, Moo Hyun; Kim, Kui Nyun; Kwang, Hung Sik; Park, Sung Joo [Pohang Accelerator Laboratory, Pohang (Korea, Republic of)

1996-12-01

Nuclear data which have been produced by a few developed countries in the= past are essential elements to many disciplines, especially to nuclear engineering. As we promote our nuclear industry further to the level of advanced countries, we also have to establish the Nuclear Data System to produce and evaluate nuclear data independently. We have studied the possibility to build a neutron-beam facility utilizing accelerator facilities, technologies and man powers at pohang Accelerator Laboratory. We found specific parameters for the PAL 100-MeV electron linac based on the existing klystron, modulator, accelerating tubes and other facilities in the PAL; the beam energy is 60-100 MeV, the beam current for the short pulse (10 ns) is 2 A and for the long pulse is 500 mA and the pulse repetition rate is 60 Hz. We propose a neutron-beam facility using PAL 100-MeV electron linac where we can use a Ta-target for the neutron generation and three different time-of-flight beam lines (10 m, 20 m, and 100 m). One may find that the proposed neutron-beam facility is comparable with other operating neutron facilities in the world. We conclude that the proposed neutron-beam facility utilizing the existing accelerator facility in the PAL would be an excellent facility for neutron data production in combination with the ` Hanaro` facility in KAERI. 8 refs., 11 tabs., 12 figs. (author)

External quality assurance performance of clinical research laboratories in sub-saharan Africa.

Science.gov (United States)

Amukele, Timothy K; Michael, Kurt; Hanes, Mary; Miller, Robert E; Jackson, J Brooks

2012-11-01

Patient Safety Monitoring in International Laboratories (JHU-SMILE) is a resource at Johns Hopkins University that supports and monitors laboratories in National Institutes of Health-funded international clinical trials. To determine the impact of the JHU-SMILE quality assurance scheme in sub-Saharan African laboratories, we reviewed 40 to 60 months of external quality assurance (EQA) results of the College of American Pathologists (CAP) in these laboratories. We reviewed the performance of 8 analytes: albumin, alanine aminotransferase, creatinine, sodium, WBC, hemoglobin, hematocrit, and the human immunodeficiency virus antibody rapid test. Over the 40- to 60-month observation period, the sub-Saharan laboratories had a 1.63% failure rate, which was 40% lower than the 2011 CAP-wide rate of 2.8%. Seventy-six percent of the observed EQA failures occurred in 4 of the 21 laboratories. These results demonstrate that a system of remote monitoring, feedback, and audits can support quality in low-resource settings, even in places without strong regulatory support for laboratory quality.

Review of JT-60 experimental results from January to March, 1987

International Nuclear Information System (INIS)

1987-08-01

This is a prompt report on JT-60 experimental results from January to March, 1987. Maximum LHRF injection power of 6.3 MW was achieved by using 3 launchers. The correlation between flattening of plasma current profile and energy confinement improvement was demonstrated by controlling N 11 spectrum of current drive and heating launchers. The maximum electron temperature of 6 kW was achieved with 2.4 MW LH injection in electron heating mode. Non-inductive driven current of 2 MA with 2.5 sec duration was demonstrated with 3 MW LHRF injection. Substantial acceleration of NB injected fast ions up to 160 kW was observed during ICRF + NB (60 keV) injection. In low density high power NB injected limiter discharges, high ion temperature of ∼ 11 keV and electron temperature of 5 keV were obtained with Z eff = 5. Various attempts were made to produce H-mode in divertor and limiter discharges. (author)

Semiconductor laser joint study program with Rome Laboratory

Science.gov (United States)

Schaff, William J.; Okeefe, Sean S.; Eastman, Lester F.

1994-09-01

A program to jointly study vertical-cavity surface emitting lasers (VCSEL) for high speed vertical optical interconnects (VOI) has been conducted under an ES&E between Rome Laboratory and Cornell University. Lasers were designed, grown, and fabricated at Cornell University. A VCSEL measurement laboratory has been designed, built, and utilized at Rome Laboratory. High quality VCSEL material was grown and characterized by fabricating conventional lateral cavity lasers that emitted at the design wavelength of 1.04 microns. The VCSEL's emit at 1.06 microns. Threshold currents of 16 mA at 4.8 volts were obtained for 30 microns diameter devices. Output powers of 5 mW were measured. This is 500 times higher power than from the light emitting diodes employed previously for vertical optical interconnects. A new form of compositional grading using a cosinusoidal function has been developed and is very successful for reducing diode series resistance for high speed interconnection applications. A flip-chip diamond package compatible with high speed operation of 16 VCSEL elements has been designed and characterized. A flip-chip device binding effort at Rome Laboratory was also designed and initiated. This report presents details of the one-year effort, including process recipes and results.

Integrated Fuel-Coolant Interaction (IFCI 6.0) code

International Nuclear Information System (INIS)

Davis, F.J.; Young, M.F.

1994-04-01

The integrated Fuel-Coolant interaction (IFCI) computer code is being developed at Sandia National Laboratories to investigate the fuel-coolant interaction (FCI) problem at large scale using a two-dimensional, four-field hydrodynamic framework and physically based models. IFCI will be capable of treating all major FCI processes in an integrated manner. This document is a product of the effort to generate a stand-alone version of IFCI, IFCI 6.0. The User's Manual describes in detail the hydrodynamic method and physical models used in IFCI 6.0. Appendix A is an input manual, provided for the creation of working decks

Laser-assisted deposition of thin C60 films

DEFF Research Database (Denmark)

Schou, Jørgen; Canulescu, Stela; Fæster, Søren

Metal and metal oxide films with controlled thickness from a fraction of a monolayer up more than 1000 nm and known stoichiometry can be produced by pulsed laser deposition (PLD) relatively easily, and (PLD) is now a standard technique in all major research laboratories within materials science...... of the matrix material, anisole, with a concentration of 0.67 wt% C60. At laser fluences below 1.5 J/cm2, a dominant fraction of the film molecules are C60 transferred to the substrate without any fragmentation. High-resolution SEM images of MAPLE deposited films reveal large circular features on the surface...

Evaluation of biodegradation of bionanocomposites of PHB/PP-g-MA/vermiculite; Avaliacao da biodegradacao de bionanocompositos de PHB/PP-g-MA/vermiculita

Energy Technology Data Exchange (ETDEWEB)

Mesquita, P.J.P. de; Alves, T.S.; Barbosa, R., E-mail: tsaeng3@yahoo.com.br [Universidade Federal do Piaui (UFPI), Teresina, PI (Brazil). Programa de Pos-Graduacao em Ciencia dos Materiais; Andrade, D. de L.A.C.S. [Universidade Federal de Campina Grande (UFCG), PB (Brazil). Programa de Pos- Graduacao em Ciencia e Engenharia de Materiais

2014-07-01

In this work, we evaluated the process of biodegradation of PHB bionanocomposites/PP-g-MA/clay. Films were prepared with compositions of 5% PP-g-MA and 3% clay (BIO5); and 2.5% PP-g-MA and 3% clay (BIO2.5). The biodegradation test was conducted according to ASTM G 160-03 for a period of 86 days. The evaluation of biodegradation was performed by optical microscopy (MO), loss of mass, FTIR and XRD. The bionanocomposites presented change of coloration and appearance of fissures. As for loss in mass in the system presented loss of BIO2,5 22.5% and 25.9% BIO5, for 86 days of simulated soil exposure. We also observed by FTIR sharp reduction in intensity of the band corresponding to the C = O groups, indicating that the microbial attack promoted cleavage of the ester group links. By XRD, reduction in the intensity of the peaks and enlargements of the same with increasing exposure time, proving the biodegradation behavior of bionanocomposites. (author)

Računalniška izdelava ocenjevalne razdelitve na mednarodnih razstavah mačk

OpenAIRE

LAMPER, DEAN

2018-01-01

Na mednarodni razstavi mačk je potrebno prijavljene mačke razdeliti med sodnike, da jih ocenijo. Pri pripravi te razdelitve je potrebno upoštevati mnogo kriterijev, prijavljenih mačk pa je lahko nekaj sto. Zahtevnost priprave dobre razdelitve tako presega človeške zmožnosti, zato smo želeli razdelitev mačk med sodnike optimizirati z metodami umetne inteligence. V nalogi je predstavljeno nekaj algoritmov, ki jih je mogoče uporabiti za izdelavo ocenjevalne razdelitve na mednarodni razstavi m...

« ImpersoNations » : cinéma national, imaginaires historiques et nouveau cinéma européen

OpenAIRE

Elsaesser, Thomas

2014-01-01

La question du capital culturel propre à la diversité linguistique de l’Europe reste entière. Quels sont les avantages et les inconvénients de cet éventail de langues dans le cinéma ? Les films, quand ils franchissent les frontières, sont souvent doublés. Or, comme un bon jeu d’acteur représente une symbiose très particulière entre le corps, la gestuelle, la voix et l’intonation, les amateurs de cinéma ne peuvent se passer des films tournés dans leur propre langue. A l’instar du son, qui revê...

The Cost-Effective Laboratory: Implementation of Economic Evaluation of Laboratory Testing

Directory of Open Access Journals (Sweden)

Bogavac-Stanojevic Natasa

2017-09-01

Full Text Available Laboratory testing as a part of laboratory in vitro diagnostic (IVD has become required tool in clinical practice for diagnosing, monitoring and prognosis of diseases, as well as for prediction of treatment response. The number of IVD tests available in laboratory practice has increased over the past decades and is likely to further increase in the future. Consequently, there is growing concern about the overutilization of laboratory tests and rising costs for laboratory testing. It is estimated that IVD accounts for between 1.4 and 2.3% of total healthcare expenditure and less than 5% of total hospital cost (Lewin Group report. These costs are rather low when compared to pharmaceuticals and medical aids which account for 15 and 5%, respectively. On the other hand, IVD tests play an important role in clinical practice, as they influence from 60% to 70% of clinical decision-making. Unfortunately, constant increases in healthcare spending are not directly related to healthcare benefit. Since healthcare resources are limited, health payers are interested whether the benefits of IVD tests are actually worth their cost. Many articles have introduced frameworks to assess the economic value of IVD tests. The most appropriate tool for quantitative assessment of their economic value is cost-effectiveness (CEA and cost-utility (CUA analysis. The both analysis determine cost in terms of effectiveness or utilities (combine quantity and quality of life of new laboratory test against its alternative. On the other hand, some investigators recommended calculation of laboratory test value as product of two ratios: Laboratory test value = (Technical accuracy/Turnaround time × (Utility/Costs. Recently, some researches used multicriteria decision analysis which allows comparison of diagnostic strategies in terms of benefits, opportunities, costs and risks. All analyses are constructed to identify laboratory test that produce the greatest healthcare benefit with

Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor.

Science.gov (United States)

Roelofs, Maarke J E; van den Berg, Martin; Bovee, Toine F H; Piersma, Aldert H; van Duursen, Majorie B M

2015-03-02

Although much information on the endocrine activity of bisphenol A (BPA) is available, a proper human hazard assessment of analogues that are believed to have a less harmful toxicity profile is lacking. Here the possible effects of BPA, bisphenol F (BPF), bisphenol S (BPS), as well as the brominated structural analogue and widely used flame retardant tetrabromobisphenol A (TBBPA) on human glucocorticoid and androgen receptor (GR and AR) activation were assessed. BPA, BPF, and TBBPA showed clear GR and AR antagonism with IC50 values of 67 μM, 60 μM, and 22 nM for GR, and 39 μM, 20 μM, and 982 nM for AR, respectively, whereas BPS did not affect receptor activity. In addition, murine MA-10 Leydig cells exposed to the bisphenol analogues were assessed for changes in secreted steroid hormone levels. Testicular steroidogenesis was altered by all bisphenol analogues tested. TBBPA effects were more directed towards the male end products and induced testosterone synthesis, while BPF and BPS predominantly increased the levels of progestagens that are formed in the beginning of the steroidogenic pathway. The MA-10 Leydig cell assay shows added value over the widely used H295R steroidogenesis assay because of its fetal-like characteristics and specificity for the physiologically more relevant testicular Δ4 steroidogenic pathway. Therefore, adding an in vitro assay covering fetal testicular steroidogenesis, such as the MA-10 cell line, to the panel of tests used to screen potential endocrine disruptors, is highly recommendable. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Photoprotection and photoreception of intraocular lenses under xenon and white LED illumination.

Science.gov (United States)

Artigas, J M; Navea, A; García-Domene, M C; Artigas, C; Lanzagorta, A

2016-05-01

To analyze the photoprotection and phototransmission that various intraocular lenses (IOLs) provide under the illumination of a xenon (Xe) lamp and white LEDs (light emitting diode). The spectral transmission curves of six representative IOLs were measured using a Perkin-Elmer Lambda 35 UV/VIS spectrometer. Various filtering simulations were performed using a Xe lamp and white LEDs. The spectral emissions of these lamps were measured with an ILT-950 spectroradiometer. The IOLs analyzed primarily show transmission of nearly 100% in the visible spectrum. In the ultraviolet (UV) region, the filters incorporated in the various IOLs did not filter equally, and some of them let an appreciable amount of UV through. The Xe lamp presented a strong emission of ultraviolet A (UVA), and its emission under 300nm was not negligible. The white LED did not present an appreciable emission under 380nm. The cut-off wavelength of most filters is between 380 and 400nm (Physiol Hydriol60C(®), IOLTECH E4T(®), Alcon SA60AT(®), Alcon IQ SN60WF(®)), so that their UV protection is very effective. Nonetheless, the IOL OPHTEC Oculaid(®) contains a filter that, when a Xe lamp is used, lets through up to 20% for 350nm and up to 15% for 300nm, which at this point is ultraviolet B (UVB). The OPHTEC(®) Artisan IOL has a transmission peak below 300nm, which must be taken into account under Xe illumination. White LEDs do not emit energy below 380nm, so no special protection is required in the UV region. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Global energy confinement in JT-60 neutral beam heated L-mode discharges

International Nuclear Information System (INIS)

Naito, O.; Hosogane, N.; Tsuji, S.; Ushigusa, K.; Yoshida, H.

1990-01-01

The global energy confinement characteristics of neutral beam heated JT-60 discharges are presented. There is a difference in the dependence of the energy confinement time on the plasma current between limiter and divertor discharges. For limiter discharges, the energy confinement increases with plasma current up to 3.2 MA, whereas for divertor discharges this improvement saturates when the safety factor drops below 3, independent of the location of the X-point. The JT-60 L-mode results indicate that the deterioration in energy confinement for q < 3, which is also found in H-mode regimes of other devices, may be a universal characteristic of divertor discharges. Regarding the scaling with plasma size, it is shown that the global/incremental confinement time increases with plasma minor radius. For sufficiently large plasmas, however, the global/incremental confinement time is no longer a function of minor radius. (author). 13 refs, 14 figs

Paraneoplastic brain stem encephalitis in a woman with anti-Ma2 antibody.

Science.gov (United States)

Barnett, M; Prosser, J; Sutton, I; Halmagyi, G M; Davies, L; Harper, C; Dalmau, J

2001-02-01

A woman developed brain stem encephalopathy in association with serum anti-Ma2 antibodies and left upper lobe lung mass. T2 weighted MRI of the brain showed abnormalities involving the pons, left middle and superior cerebellar peduncles, and bilateral basal ganglia. Immunohistochemical analysis for serum antineuronal antibodies was confounded by the presence of a non-neuronal specific antinuclear antibody. Immunoblot studies showed the presence of anti-Ma2 antibodies. A premortem tissue diagnosis of the lung mass could not be established despite two CT guided needle biopsies, and the patient died as a result of rapid neurological deterioration. The necropsy showed that the lung lesion was an adenocarcinoma which expressed Ma2 immunoreactive protein. Neuropathological findings included prominent perivascular inflammatory infiltrates, glial nodules, and neuronophagia involving the brain stem, basal ganglia, hippocampus and the dentate nucleus of the cerebellum. Ma2 is an autoantigen previously identified in patients with germ cell tumours of the testis and paraneoplastic brain stem and limbic encephalitis. Our patient's clinical and immunopathological findings indicate that this disorder can affect women with lung adenocarcinoma, and that the encephalitic changes predominate in those regions of the brain known to express high concentrations of Ma proteins.

Are laboratory tests always needed? Frequency and causes of laboratory overuse in a hospital setting.

Science.gov (United States)

Cadamuro, Janne; Gaksch, Martin; Wiedemann, Helmut; Lippi, Giuseppe; von Meyer, Alexander; Pertersmann, Astrid; Auer, Simon; Mrazek, Cornelia; Kipman, Ulrike; Felder, Thomas K; Oberkofler, Hannes; Haschke-Becher, Elisabeth

2018-04-01

Inappropriate utilization of laboratory resources is an increasing concern especially in high-throughput facilities. Until now, no reliable information has been published addressing to which extent laboratory results are actually used for clinical decision-making. Therefore, we aimed to close this gap using a novel retrospective approach including a survey of clinicians and nurses. We retrospectively evaluated the number of re-orders for potassium (K), lactate dehydrogenase (LD), aspartate-aminotransferase (AST), activated partial thromboplastin-time (APTT) and prothrombin-time/INR (PT/INR), after the initial order had to be cancelled due to preanalytical non-conformities. We analyzed subgroups regarding time to re-order, ward and sample priority (urgent vs. routine). Subsequently, we surveyed clinicians and nurses, asking for their estimate of the amount of failed re-orders as well as for possible reasons. From initially cancelled tests, only ~20% of K, LD, AST and ~30% of APTT and PT/INR tests were re-ordered within 24 h. 70% of the investigated clinical chemistry and 60% of coagulation tests were re-ordered one week after cancellation or not at all. Survey participants quite accurately estimated these numbers. Routine laboratory panels, short stay of out-patients, obsolete test results and avoiding additional phlebotomies were the main reasons for not re-ordering cancelled tests. Overall, 60-70% of test results in the investigated assays ordered in a high throughput laboratory are potentially inappropriate or of doubtful clinically importance. Although clinicians and nurses are aware of this situation, it is the duty of laboratory specialists to overcome overutilization in close collaboration with all involved healthcare workers. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

Stormwater Pollution Prevention Plan - TA-60 Asphalt Batch Plant

Energy Technology Data Exchange (ETDEWEB)

Sandoval, Leonard Frank [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2018-01-31

This Storm Water Pollution Prevention Plan (SWPPP) was developed in accordance with the provisions of the Clean Water Act (33 U.S.C. §§1251 et seq., as amended), and the Multi-Sector General Permit for Storm Water Discharges Associated with Industrial Activity (U.S. EPA, June 2015) issued by the U.S. Environmental Protection Agency (EPA) for the National Pollutant Discharge Elimination System (NPDES) and using the industry specific permit requirements for Sector P-Land Transportation and Warehousing as a guide. This SWPPP applies to discharges of stormwater from the operational areas of the TA-60-01 Asphalt Batch Plant at Los Alamos National Laboratory. Los Alamos National Laboratory (also referred to as LANL or the “Laboratory”) is owned by the Department of Energy (DOE), and is operated by Los Alamos National Security, LLC (LANS). Throughout this document, the term “facility” refers to the TA-60 Asphalt Batch Plant and associated areas. The current permit expires at midnight on June 4, 2020.

Stormwater Pollution Prevention Plan - TA-60 Material Recycling Facility

Energy Technology Data Exchange (ETDEWEB)

Sandoval, Leonard Frank [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2018-01-31

This Storm Water Pollution Prevention Plan (SWPPP) was developed in accordance with the provisions of the Clean Water Act (33 U.S.C. §§1251 et seq., as amended), and the Multi-Sector General Permit for Storm Water Discharges Associated with Industrial Activity (U.S. EPA, June 2015) issued by the U.S. Environmental Protection Agency (EPA) for the National Pollutant Discharge Elimination System (NPDES) and using the industry specific permit requirements for Sector P-Land Transportation and Warehousing as a guide. This SWPPP applies to discharges of stormwater from the operational areas of the TA- 60 Material Recycling Facility at Los Alamos National Laboratory. Los Alamos National Laboratory (also referred to as LANL or the “Laboratory”) is owned by the Department of Energy (DOE), and is operated by Los Alamos National Security, LLC (LANS). Throughout this document, the term “facility” refers to the TA-60 Material Recycling Facility. The current permit expires at midnight on June 4, 2020.

Comparison of TCeMA and TDMA for Inter-Satellite Communications using OPNET Simulation

Science.gov (United States)

Hain, Regina Rosales; Ramanathan, Ram; Bergamo, Marcos; Wallett, Thomas M.

2003-01-01

A robust data link protocol, enabling unique physical and MAC layer technologies and sub-network level protocols, is needed in order to take advantage of the full potential of using both TDMA and CDMA in a satellite communication network. A novel MAC layer protocol, TDMA with CDMA-encoding multiple access (TCeMA) integrated with null-steered digital beam-forming spatial multiplexing, is investigated to support flexible spacecraft communications. Abstract models of the TCeMA and TDMA processes are developed in OPNFiT and a comparison of the performances of TCeMA and TDMA in a satellite network simulation are made. TCeMA provides the better connectivity and capacity with respect to TDMA for satellite communication traffic.

Predicting Sediment Thickness on Vanished Ocean Crust Since 200 Ma

Science.gov (United States)

Dutkiewicz, A.; Müller, R. D.; Wang, X.; O'Callaghan, S.; Cannon, J.; Wright, N. M.

2017-12-01

Tracing sedimentation through time on existing and vanished seafloor is imperative for constraining long-term eustasy and for calculating volumes of subducted deep-sea sediments that contribute to global geochemical cycles. We present regression algorithms that incorporate the age of the ocean crust and the mean distance to the nearest passive margin to predict sediment thicknesses and long-term decompacted sedimentation rates since 200 Ma. The mean sediment thickness decreases from ˜220 m at 200 Ma to a minimum of ˜140 m at 130 Ma, reflecting the replacement of old Panthalassic ocean floor with young sediment-poor mid-ocean ridges, followed by an increase to ˜365 m at present-day. This increase reflects the accumulation of sediments on ageing abyssal plains proximal to passive margins, coupled with a decrease in the mean distance of any parcel of ocean crust to the nearest passive margin by over 700 km, and a doubling of the total passive margin length at present-day. Mean long-term sedimentation rates increase from ˜0.5 cm/ky at 160 Ma to over 0.8 cm/ky today, caused by enhanced terrigenous sediment influx along lengthened passive margins, superimposed by the onset of ocean-wide carbonate sedimentation. Our predictive algorithms, coupled to a plate tectonic model, provide a framework for constraining the seafloor sediment-driven eustatic sea-level component, which has grown from ˜80 to 210 m since 120 Ma. This implies a long-term sea-level rise component of 130 m, partly counteracting the contemporaneous increase in ocean basin depth due to progressive crustal ageing.

Ma_MISS on ExoMars: Mineralogical Characterization of the Martian Subsurface

Science.gov (United States)

De Sanctis, Maria Cristina; Altieri, Francesca; Ammannito, Eleonora; Biondi, David; De Angelis, Simone; Meini, Marco; Mondello, Giuseppe; Novi, Samuele; Paolinetti, Riccardo; Soldani, Massimo; Mugnuolo, Raffaele; Pirrotta, Simone; Vago, Jorge L.; Ma_MISS Team

2017-07-01

The Ma_MISS (Mars Multispectral Imager for Subsurface Studies) experiment is the visible and near infrared (VNIR) miniaturized spectrometer hosted by the drill system of the ExoMars 2020 rover. Ma_MISS will perform IR spectral reflectance investigations in the 0.4-2.2 μm range to characterize the mineralogy of excavated borehole walls at different depths (between 0 and 2 m). The spectral sampling is about 20 nm, whereas the spatial resolution over the target is 120 μm. Making use of the drill's movement, the instrument slit can scan a ring and build up hyperspectral images of a borehole. The main goal of the Ma_MISS instrument is to study the martian subsurface environment. Access to the martian subsurface is crucial to our ability to constrain the nature, timing, and duration of alteration and sedimentation processes on Mars, as well as habitability conditions. Subsurface deposits likely host and preserve H2O ice and hydrated materials that will contribute to our understanding of the H2O geochemical environment (both in the liquid and in the solid state) at the ExoMars 2020 landing site. The Ma_MISS spectral range and sampling capabilities have been carefully selected to allow the study of minerals and ices in situ before the collection of samples. Ma_MISS will be implemented to accomplish the following scientific objectives: (1) determine the composition of subsurface materials, (2) map the distribution of subsurface H2O and volatiles, (3) characterize important optical and physical properties of materials (e.g., grain size), and (4) produce a stratigraphic column that will inform with regard to subsurface geological processes. The Ma_MISS findings will help to refine essential criteria that will aid in our selection of the most interesting subsurface formations from which to collect samples.

MHD PbLi experiments in MaPLE loop at UCLA

International Nuclear Information System (INIS)

Courtessole, C.; Smolentsev, S.; Sketchley, T.; Abdou, M.

2016-01-01

Highlights: • The paper overviews the MaPLE facility at UCLA: one-of-a-few PbLi MHD loop in the world. • We present the progress achieved in development and testing of high-temperature PbLi flow diagnostics. • The most important MHD experiments carried out since the first loop operation in 2011 are summarized. - Abstract: Experiments on magnetohydrodynamic (MHD) flows are critical to understanding complex flow phenomena in ducts of liquid metal blankets, in particular those that utilize eutectic alloy lead–lithium as breeder/coolant, such as self-cooled, dual-coolant and helium-cooled lead–lithium blanket concepts. The primary goal of MHD experiments at UCLA using the liquid metal flow facility called MaPLE (Magnetohydrodynamic PbLi Experiment) is to address important MHD effects, heat transfer and flow materials interactions in blanket-relevant conditions. The paper overviews the one-of-a-kind MaPLE loop at UCLA and presents recent experimental activities, including the development and testing of high-temperature PbLi flow diagnostics and experiments that have been performed since the first loop operation in 2011. We also discuss MaPLE upgrades, which need to be done to substantially expand the experimental capabilities towards a new class of MHD flow phenomena that includes buoyancy effects.

MHD PbLi experiments in MaPLE loop at UCLA

Energy Technology Data Exchange (ETDEWEB)

Courtessole, C., E-mail: cyril@fusion.ucla.edu; Smolentsev, S.; Sketchley, T.; Abdou, M.

2016-11-01

Highlights: • The paper overviews the MaPLE facility at UCLA: one-of-a-few PbLi MHD loop in the world. • We present the progress achieved in development and testing of high-temperature PbLi flow diagnostics. • The most important MHD experiments carried out since the first loop operation in 2011 are summarized. - Abstract: Experiments on magnetohydrodynamic (MHD) flows are critical to understanding complex flow phenomena in ducts of liquid metal blankets, in particular those that utilize eutectic alloy lead–lithium as breeder/coolant, such as self-cooled, dual-coolant and helium-cooled lead–lithium blanket concepts. The primary goal of MHD experiments at UCLA using the liquid metal flow facility called MaPLE (Magnetohydrodynamic PbLi Experiment) is to address important MHD effects, heat transfer and flow materials interactions in blanket-relevant conditions. The paper overviews the one-of-a-kind MaPLE loop at UCLA and presents recent experimental activities, including the development and testing of high-temperature PbLi flow diagnostics and experiments that have been performed since the first loop operation in 2011. We also discuss MaPLE upgrades, which need to be done to substantially expand the experimental capabilities towards a new class of MHD flow phenomena that includes buoyancy effects.

Aladağlar’da [Orta Toroslar (Yahyalı-Kayseri)] iki fosil mağara: Zindan-ı Köşk–1 ve Zindan-ı Köşk-2 mağaraları

OpenAIRE

Kopar, İbrahim

2015-01-01

Zindan-ı Köşk-1 ve Zindan-ı Köşk-2 Mağaraları, jeomorfolojik olarak Toros Dağları’nın Orta Toros Bölümü’nün doğusundaki Aladağlarda (en yüksek tepesi 3756 m) yer almaktadır. İdari bakımdan ise Kayseri İlinin Yahyalı ilçesi sınırlarında yer alan mağaralar, naplı yapıya sahip Permiyen kalkerler içinde gelişmiştir. Zindan Deresi’nin 500 metreden fazla yardığı adinin güney yamacında 2095 m ve 2115 metrede giriş ağızları olan mağaralardan üstteki Zindan-ı Köşk-1 Mağarası dikey gelişmiş bir mağara ...

Changing the Safety and Mission Assurance (S and MA) Paradigm

Science.gov (United States)

Malone, Roy W.; Safie, Fayssal M.

2010-01-01

This slide presentation reviews the change in the work and impact of the Safety and Mission Assurance directorate at Marshall Space Flight Center. It reviews the background and the reasons given for a strong Safety & Mission Assurance presence in all planning for space flight. This was pointed out by the Rogers Commission Report after the Space Challenger accident, by the Columbia Accident Investigation Board (CAIB) and by a 2006 NASA Exploration Safety Study (NESS) Team. The overall objective of the work in this area was to improve and maintain S&MA expertise and skills. Training for this work was improved and the S&MA organization was reorganized. This has resulted in a paradigm shift for NASA's safety efforts, which is described. The presentation then reviews the impact of the new S&MA work in the Ares I design and development.

Periodic modulations controlling Kuznetsov–Ma soliton formation in nonlinear Schrödinger equations

Energy Technology Data Exchange (ETDEWEB)

Tiofack, C.G.L., E-mail: glatchio@yahoo.fr [Univ. Lille, CNRS, UMR 8523 – PhLAM – Physique des Lasers Atomes et Molécules, F-59000 Lille (France); Coulibaly, S.; Taki, M. [Univ. Lille, CNRS, UMR 8523 – PhLAM – Physique des Lasers Atomes et Molécules, F-59000 Lille (France); De Bièvre, S.; Dujardin, G. [Univ. Lille, CNRS, UMR 8524 – Laboratoire Paul Painlevé, F-59000 Lille (France); Équipe-Projet Mephysto, INRIA Lille-Nord Europe (France)

2017-06-28

We analyze the exact Kuznetsov–Ma soliton solution of the one-dimensional nonlinear Schrödinger equation in the presence of periodic modulations satisfying an integrability condition. We show that, in contrast to the case without modulation, the Kuznetsov–Ma soliton develops multiple compression points whose number, shape and position are controlled both by the intensity of the modulation and by its frequency. In addition, when this modulation frequency is a rational multiple of the natural frequency of the Kuznetsov–Ma soliton, a scenario similar to a nonlinear resonance is obtained: in this case the spatial oscillations of the Kuznetsov–Ma soliton's intensity are periodic. When the ratio of the two frequencies is irrational, the soliton's intensity is a quasiperiodic function. A striking and important result of our analysis is the possibility to suppress any component of the output spectrum of the Kuznetsov–Ma soliton by a judicious choice of the amplitude and frequency of the modulation. - Highlights: • Exact Kuznetsov–Ma soliton solution in presence of periodic coefficients is obtained. • The multiple compression points of the solution are studied. • The quasi-periodicity of the solution is discussed. • The possibility to suppress any component of the spectrum is analyzed.

Relationship between endothelial cell loss and microcoaxial phacoemulsification parameters in noncomplicated cataract surgery

Directory of Open Access Journals (Sweden)

Soliman Mahdy MAE

2012-03-01

Full Text Available Mohamed AE Soliman Mahdy1,2, Mohamed Z Eid1, Mahmoud Abdel-Badei Mohammed3, Amr Hafez4,5, Jagdish Bhatia21Ophthalmic Department, Al-Hussein University Hospital, Al-Azhar University, Cairo, Egypt; 2Ophthalmic Department, Rustaq Hospital, Rustaq, Sultanate of Oman; 3Research Institute of Ophthalmology, Cairo, Egypt; 4Magrabi Eye and Ear Center, Muscat, Sultanate of Oman; 5Ophthalmic Department, Al-Azhar University Hospital, Assuit, EgyptPurpose: To assess the relationship between postoperative endothelial cell loss and microcoaxial phaco parameters using Ozil IP (Alcon Laboratories, Inc, Fort Worth, TX in noncomplicated cataract surgery.Methods: In this prospective observational study, 120 consecutive cases of cataract patients with different grades of nuclear hardness underwent microcoaxial phacoemulsification through a 2.2-mm clear corneal incision. An Alcon Infinity Vision System with Ozil IP (Alcon Laboratories was used with an Ozil torsional handpiece and a Kelman-style 45° phacoemulsification tip. Patients underwent preoperative and postoperative central endothelial cell counts.Results: The study included 120 cases of age-related cataract whose mean age (standard deviation [SD] was 59.68 years (9.47. There was a highly statistically significant endothelial cell loss (P < 0.001. The endothelial cell loss ranged 11–1149 cells/mm2 with a median (interquartile range of 386 cells/mm2 (184.5–686 cells/mm2. The percentage of postoperative ECLoss% ranged from 0.48% to 47.8% with a median (interquartile range of 15.4% (7.2% to 26.8%. A significant positive correlation was found between the ECLoss% and different phaco parameters. The Spearman’s rank-order correlation coefficient values, rho, (ρ were as follows: CDE (ρ = 0.425, aspiration time (ρ = 0.176, and volume (ρ = 0.278. Also, ECLoss% was significantly correlated with the grade of nuclear opalescence (Kendall’s tau τ = 0.42.Conclusion: Microcoaxial phacoemulsification was efficient

Radioanalytical laboratory quality control: Current status at Tennessee Valley Authority's western area radiological laboratory

International Nuclear Information System (INIS)

Rogers, W.J.

1986-01-01

The Tennessee Valley Authority operates a laboratory for radiological analysis of nuclear plant environmental monitoring samples and also for analysis of environmental samples from uranium mining and milling decommissioning activities. The laboratory analyzes some 9,000 samples per year and employs approximately 20 people as analysts, sample collectors, and supervisory staff members. The laboratory is supported by a quality control section of four people involved in computer support, production of radioactive standards, quality control data assessment and reporting, and internal reviews of compliance. The entire laboratory effort is controlled by 60 written procedures or standards. An HP-1000 computer and data base software are used to schedule samples for collection, assign and schedule samples within the laboratory for preparation and analysis, calculate sample activity, review data, and report data outside the laboratory. Gamma spectroscopy systems with nine germanium detectors, an alpha spectroscopy system, five alpha/beta counters, two liquid scintillation counters, four beta-gamma coincidence systems, two sodium iodide single-channel systems, and four photomultipliers for counting Lucas cells are all employed. Each device has various calibration and quality control checks performed on it routinely. Logbooks and control charts are in use for each instrument

ImpersoNations: cinéma national, imaginaires historiques et nouveau cinéma européen

NARCIS (Netherlands)

Elsaesser, T.

2013-01-01

La question du capital culturel propre à la diversité linguistique de l’Europe reste entière. Quels sont les avantages et les inconvénients de cet éventail de langues dans le cinéma? Les films, quand ils franchissent les frontières, sont souvent doublés. Or, comme un bon jeu d’acteur représente une

Human Factors Assessment of the UH-60M Crew Station During the Limited User Test (LUT)

National Research Council Canada - National Science Library

Havir, Thomas J; Durbin, David B; Frederick, Lorraine J; Hicks, Jamison S

2006-01-01

The utility helicopter (UH)-60M Product Manager requested the U.S. Army Research Laboratory's Human Research and Engineering Directorate to participate in the Limited User Test for the UH-60M Black Hawk...

Correlating The Star Formation Histories Of MaNGA Galaxies With Their Past AGN Activity

Science.gov (United States)

Gonzalez Ortiz, Andrea

2017-01-01

We investigate active galactic nuclei (AGN) as a primary mechanism affecting star formation in MaNGA galaxies. Using the Pipe3D code, we modeled the stellar population from MaNGA spectra and derived the star formation histories of 53 AGN host galaxies. We seek to compare the star formation histories of the host galaxies of AGN with the ages of their radio lobes to better understand the role of AGN feedback in the star formation histories of MaNGA galaxies. MaNGA (Mapping Nearby Galaxies at APO) is one of the three core programs in the fourth generation Sloan Digital Sky Survey(SDSS). MaNGA will investigate the internal kinematics of nearly 10,000 local galaxies through dithered observations using fiber integral field units (IFUs) that vary in diameter from 12" (19 fibers) to 32" (127 fibers). In this poster, we present initial results on the star formation histories of MaNGA AGN host galaxies. This work was supported by the SDSS Research Experience for Undergraduates program, which is funded by a grant from Sloan Foundation to the Astrophysical Research Consortium.

Ma Ying-jeou’s Presidential Discourse

Directory of Open Access Journals (Sweden)

Jonathan Sullivan

2012-01-01

Full Text Available Despite the substantial advances made in cross-Strait relations during Ma Ying-jeou’s (Ma Yingjiu first term, the ROC president’s rhetoric varied considerably as he grappled with the difficult reality of implementing campaign and inauguration pledges to establish better relations with China while striving to maintain national respect and sovereignty. In this article, we put forward a framework for measuring, analysing and explaining this variation in President Ma’s first-term discourse. Analysing a very large number of Ma’s speeches, addresses, etc., we provide empirical assessments of how the content of Ma’s public pronouncements has developed over time, how his rhetoric varies according to the strategic context and timing of a speech, and how his discourse compares to that of his predecessor, Chen Shui-bian (Chen Shuibian. In addressing these questions, the article contributes a quantitative perspective to existing work on political discourse in Taiwan and to the growing methodological and applied literature on how to systematically analyse Chinese political text.

National survey on intra-laboratory turnaround time for some most common routine and stat laboratory analyses in 479 laboratories in China.

Science.gov (United States)

Fei, Yang; Zeng, Rong; Wang, Wei; He, Falin; Zhong, Kun; Wang, Zhiguo

2015-01-01

To investigate the state of the art of intra-laboratory turnaround time (intra-TAT), provide suggestions and find out whether laboratories accredited by International Organization for Standardization (ISO) 15189 or College of American Pathologists (CAP) will show better performance on intra-TAT than non-accredited ones. 479 Chinese clinical laboratories participating in the external quality assessment programs of chemistry, blood gas, and haematology tests organized by the National Centre for Clinical Laboratories in China were included in our study. General information and the median of intra-TAT of routine and stat tests in last one week were asked in the questionnaires. The response rate of clinical biochemistry, blood gas, and haematology testing were 36% (479/1307), 38% (228/598), and 36% (449/1250), respectively. More than 50% of laboratories indicated that they had set up intra-TAT median goals and almost 60% of laboratories declared they had monitored intra-TAT generally for every analyte they performed. Among all analytes we investigated, the intra-TAT of haematology analytes was shorter than biochemistry while the intra-TAT of blood gas analytes was the shortest. There were significant differences between median intra-TAT on different days of the week for routine tests. However, there were no significant differences in median intra-TAT reported by accredited laboratories and non-accredited laboratories. Many laboratories in China are aware of intra-TAT control and are making effort to reach the target. There is still space for improvement. Accredited laboratories have better status on intra-TAT monitoring and target setting than the non-accredited, but there are no significant differences in median intra-TAT reported by them.

SCHeMA web-based observation data information system

Science.gov (United States)

Novellino, Antonio; Benedetti, Giacomo; D'Angelo, Paolo; Confalonieri, Fabio; Massa, Francesco; Povero, Paolo; Tercier-Waeber, Marie-Louise

2016-04-01

It is well recognized that the need of sharing ocean data among non-specialized users is constantly increasing. Initiatives that are built upon international standards will contribute to simplify data processing and dissemination, improve user-accessibility also through web browsers, facilitate the sharing of information across the integrated network of ocean observing systems; and ultimately provide a better understanding of the ocean functioning. The SCHeMA (Integrated in Situ Chemical MApping probe) Project is developing an open and modular sensing solution for autonomous in situ high resolution mapping of a wide range of anthropogenic and natural chemical compounds coupled to master bio-physicochemical parameters (www.schema-ocean.eu). The SCHeMA web system is designed to ensure user-friendly data discovery, access and download as well as interoperability with other projects through a dedicated interface that implements the Global Earth Observation System of Systems - Common Infrastructure (GCI) recommendations and the international Open Geospatial Consortium - Sensor Web Enablement (OGC-SWE) standards. This approach will insure data accessibility in compliance with major European Directives and recommendations. Being modular, the system allows the plug-and-play of commercially available probes as well as new sensor probess under development within the project. The access to the network of monitoring probes is provided via a web-based system interface that, being implemented as a SOS (Sensor Observation Service), is providing standard interoperability and access tosensor observations systems through O&M standard - as well as sensor descriptions - encoded in Sensor Model Language (SensorML). The use of common vocabularies in all metadatabases and data formats, to describe data in an already harmonized and common standard is a prerequisite towards consistency and interoperability. Therefore, the SCHeMA SOS has adopted the SeaVox common vocabularies populated by

MaMiCo: Software design for parallel molecular-continuum flow simulations

KAUST Repository

Neumann, Philipp

2015-11-19

The macro-micro-coupling tool (MaMiCo) was developed to ease the development of and modularize molecular-continuum simulations, retaining sequential and parallel performance. We demonstrate the functionality and performance of MaMiCo by coupling the spatially adaptive Lattice Boltzmann framework waLBerla with four molecular dynamics (MD) codes: the light-weight Lennard-Jones-based implementation SimpleMD, the node-level optimized software ls1 mardyn, and the community codes ESPResSo and LAMMPS. We detail interface implementations to connect each solver with MaMiCo. The coupling for each waLBerla-MD setup is validated in three-dimensional channel flow simulations which are solved by means of a state-based coupling method. We provide sequential and strong scaling measurements for the four molecular-continuum simulations. The overhead of MaMiCo is found to come at 10%-20% of the total (MD) runtime. The measurements further show that scalability of the hybrid simulations is reached on up to 500 Intel SandyBridge, and more than 1000 AMD Bulldozer compute cores. Program summary: Program title: MaMiCo. Catalogue identifier: AEYW_v1_0. Program summary URL: http://cpc.cs.qub.ac.uk/summaries/AEYW_v1_0.html Program obtainable from: CPC Program Library, Queen\\'s University, Belfast, N. Ireland. Licensing provisions: BSD License. No. of lines in distributed program, including test data, etc.: 67905. No. of bytes in distributed program, including test data, etc.: 1757334. Distribution format: tar.gz. Programming language: C, C++II. Computer: Standard PCs, compute clusters. Operating system: Unix/Linux. RAM: Test cases consume ca. 30-50 MB. Classification: 7.7. External routines: Scons (http:www.scons.org), ESPResSo, LAMMPS, ls1 mardyn, waLBerla. Nature of problem: Coupled molecular-continuum simulation for multi-resolution fluid dynamics: parts of the domain are resolved by molecular dynamics whereas large parts are covered by a CFD solver, e.g. a lattice Boltzmann automaton

New Constraints on the Abundance of 60Fe in the Early Solar System

Science.gov (United States)

Trappitsch, Reto; Boehnke, Patrick; Stephan, Thomas; Telus, Myriam; Savina, Michael R.; Pardo, Olivia; Davis, Andrew M.; Dauphas, Nicolas; Pellin, Michael J.; Huss, Gary R.

2018-04-01

Establishing the abundance of the extinct radionuclide 60Fe (half-life 2.62 Ma) in the early solar system is important for understanding the astrophysical context of solar system formation. While bulk measurements of early solar system phases show a low abundance consistent with galactic background, some in situ measurements by secondary ion mass spectrometry (SIMS) imply a higher abundance, which would require injection from a nearby supernova (SN). Here we present in situ nickel isotopic analyses by resonance ionization mass spectrometry (RIMS) in a chondrule from the primitive meteorite Semarkona (LL3.00). The same chondrule had been previously analyzed by SIMS. Despite improved precision compared to SIMS, the RIMS nickel isotopic data do not reveal any resolved excesses of 60Ni that could be unambiguously ascribed to in situ 60Fe decay. Linear regression of 60Ni/58Ni versus 56Fe/58Ni yields an initial 60Fe/56Fe ratio for this chondrule of (3.8 ± 6.9) × 10‑8, which is consistent with both the low initial value found by bulk measurements and the low end of the range of initial ratios inferred from some in situ work. The same regression also gives a solar initial 60Ni/58Ni ratio, which shows that this sample was not disturbed by nickel mobilization, thus agreeing with a low initial 60Fe/56Fe ratio. These findings agree with a re-evaluation of previous SIMS measurements of the same sample. Supernova injection of 60Fe into the solar system or its parental cloud material is therefore not necessary to account for the measured solar system’s initial amount of 60Fe.

{sup 60}Fe measurements with the PSI/ETH EN tandem accelerator

Energy Technology Data Exchange (ETDEWEB)

Gartenmann, P.; Schnabel, C.; Suter, M. [ETHZ, Zurich (Switzerland); Synal, H.A. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

1997-09-01

First AMS measurements of the long-lived radionuclide {sup 60}Fe have been performed. At an energy of 60 MeV, the suppression of the stable isobar {sup 60}Ni is the main difficulty. Spraying hydrogen gas onto the ion source target and extracting the metal single hydrides, the nickel contamination in the beam can be reduced more than 500 fold. In the gas ionization detector another five orders of magnitude of suppression is obtained. A background {sup 60}Fe/Fe ratio of about 10{sup -11} has allowed first measurements with the standard samples used earlier at Argonne National Laboratory. The results of the two facilities are in agreement. (author) 1 fig., 5 refs.

Laboratory assessment of novel oral anticoagulants: method suitability and variability between coagulation laboratories.

Science.gov (United States)

Helin, Tuukka A; Pakkanen, Anja; Lassila, Riitta; Joutsi-Korhonen, Lotta

2013-05-01

Laboratory tests to assess novel oral anticoagulants (NOACs) are under evaluation. Routine monitoring is unnecessary, but under special circumstances bioactivity assessment becomes crucial. We analyzed the effects of NOACs on coagulation tests and the availability of specific assays at different laboratories. Plasma samples spiked with dabigatran (Dabi; 120 and 300 μg/L) or rivaroxaban (Riva; 60, 146, and 305 μg/L) were sent to 115 and 38 European laboratories, respectively. International normalized ratio (INR) and activated partial thromboplastin time (APTT) were analyzed for all samples; thrombin time (TT) was analyzed specifically for Dabi and calibrated anti-activated factor X (anti-Xa) activity for Riva. We compared the results with patient samples. Results of Dabi samples were reported by 73 laboratories (13 INR and 9 APTT reagents) and Riva samples by 22 laboratories (5 INR and 4 APTT reagents). Both NOACs increased INR values; the increase was modest, albeit larger, for Dabi, with higher CV, especially with Quick (vs Owren) methods. Both NOACs dose-dependently prolonged the APTT. Again, the prolongation and CVs were larger for Dabi. The INR and APTT results varied reagent-dependently (P laboratories, respectively. The screening tests INR and APTT are suboptimal in assessing NOACs, having high reagent dependence and low sensitivity and specificity. They may provide information, if laboratories recognize their limitations. The variation will likely increase and the sensitivity differ in clinical samples. Specific assays measure NOACs accurately; however, few laboratories applied them. © 2013 American Association for Clinical Chemistry.

MA-core loaded untuned RF compression cavity for HIRFL-CSR

International Nuclear Information System (INIS)

Mei Lirong; Xu Zhe; Yuan Youjin; Jin Peng; Bian Zhibin; Zhao Hongwei; Xia Jiawen

2012-01-01

To meet the requirements of high energy density physics and plasma physics research at HIRFL-CSR the goal of achieving a higher accelerating gap voltage was proposed. Therefore, a magnetic alloy (MA)-core loaded radio frequency (RF) cavity that can provide a higher accelerating gap voltage compared to standard ferrite loaded cavities has been studied at IMP. In order to select the proper magnetic alloy material to load the RF compression cavity, measurements of four different kinds of sample MA-cores have been carried out. By testing the small cores, the core composition was selected to obtain the desired performance. According to the theoretical calculation and simulation, which show reasonable consistency for the MA-core loaded cavity, the desired performance can be achieved. Finally about 1000 kW power will be needed to meet the requirements of 50 kV accelerating gap voltage by calculation.

Kuznetsov-Ma waves train generation in a left-handed material

Science.gov (United States)

Atangana, Jacques; Giscard Onana Essama, Bedel; Biya-Motto, Frederick; Mokhtari, Bouchra; Cherkaoui Eddeqaqi, Noureddine; Crépin Kofane, Timoléon

2015-03-01

We analyze the behavior of an electromagnetic wave which propagates in a left-handed material. Second-order dispersion and cubic-quintic nonlinearities are considered. This behavior of an electromagnetic wave is modeled by a nonlinear Schrödinger equation which is solved by collective coordinates theory in order to characterize the light pulse intensity profile. More so, a specific frequency range has been outlined where electromagnetic wave behavior will be investigated. The perfect combination of second-order dispersion and cubic nonlinearity leads to a robust soliton. When the quintic nonlinearity comes into play, it provokes strong and long internal perturbations which lead to Benjamin-Feir instability. This phenomenon, also called modulational instability, induces appearance of a Kuznetsov-Ma waves train. We numerically verify the validity of Kuznetsov-Ma theory by presenting physical conditions which lead to Kuznetsov-Ma waves train generation. Thereafter, some properties of such waves train are also verified.

DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo.

Science.gov (United States)

Zubradt, Meghan; Gupta, Paromita; Persad, Sitara; Lambowitz, Alan M; Weissman, Jonathan S; Rouskin, Silvi

2017-01-01

Coupling of structure-specific in vivo chemical modification to next-generation sequencing is transforming RNA secondary structure studies in living cells. The dominant strategy for detecting in vivo chemical modifications uses reverse transcriptase truncation products, which introduce biases and necessitate population-average assessments of RNA structure. Here we present dimethyl sulfate (DMS) mutational profiling with sequencing (DMS-MaPseq), which encodes DMS modifications as mismatches using a thermostable group II intron reverse transcriptase. DMS-MaPseq yields a high signal-to-noise ratio, can report multiple structural features per molecule, and allows both genome-wide studies and focused in vivo investigations of even low-abundance RNAs. We apply DMS-MaPseq for the first analysis of RNA structure within an animal tissue and to identify a functional structure involved in noncanonical translation initiation. Additionally, we use DMS-MaPseq to compare the in vivo structure of pre-mRNAs with their mature isoforms. These applications illustrate DMS-MaPseq's capacity to dramatically expand in vivo analysis of RNA structure.

Faculty of Law: MaRBLe for Lawyers

NARCIS (Netherlands)

Akkermans, Bram; Bastiaens, Ellen; van Tilburg, Jonathan; van Merriënboer, Jeroen

The Maastricht University Research Based Learning (MaRBLe) project offered a unique but challenging opportunity to the law faculty. Working with undergraduate (or bachelor) students on research was already part of regular, i.e. curricular, teaching activities, but the number of students and

Torsional ultrasound mode versus combined torsional and conventional ultrasound mode phacoemulsification for eyes with hard cataract.

Science.gov (United States)

Fakhry, Mohamed A; El Shazly, Malak I

2011-01-01

To compare torsional versus combined torsional and conventional ultrasound modes in hard cataract surgery regarding ultrasound energy and time and effect on corneal endothelium. Kasr El Aini hospital, Cairo University, and International Eye Hospital, Cairo, Egypt. Ninety-eight eyes of 63 patients were enrolled in this prospective comparative randomized masked clinical study. All eyes had nuclear cataracts of grades III and IV using the Lens Opacities Classification System III (LOCS III). Two groups were included, each having an equal number of eyes (49). The treatment for group A was combined torsional and conventional US mode phacoemulsification, and for group B torsional US mode phacoemulsification only. Pre- and post-operative assessments included best corrected visual acuity (BCVA), intraocular pressure (IOP), slit-lamp evaluation, and fundoscopic evaluation. Endothelial cell density (ECD) and central corneal thickness (CCT) were measured preoperatively, 1 day, 7 days, and 1 month postoperatively. All eyes were operated on using the Alcon Infiniti System (Alcon, Fort Worth, TX) with the quick chop technique. All eyes were implanted with AcrySof SA60AT (Alcon) intraocular lens (IOL). The main phaco outcome parameters included the mean ultrasound time (UST), the mean cumulative dissipated energy (CDE), and the percent of average torsional amplitude in position 3 (%TUSiP3). Improvement in BCVA was statistically significant in both groups (P < 0.001). Comparing UST and CDE for both groups revealed results favoring the pure torsional group (P = 0.002 and P < 0.001 for UST; P = 0.058 and P = 0.009 for CDE). As for %TUSiP3, readings were higher for the pure torsional group (P = 0.03 and P = 0.01). All changes of CCT, and ECD over time were found statistically significant using one-way ANOVA testing (P < 0.001). Both modes are safe in hard cataract surgery, however the pure torsional mode showed less US energy used.

European Master's program in Gerontology (EuMaG): Goals, curriculum, and students

NARCIS (Netherlands)

Aartsen, M.J.

2011-01-01

The European Master's Program in Gerontology (EuMaG) started in September 2003 with support from the European Commission. The EuMaG is a modular, 2-year, part-time international training program about the aging process and its societal implications. The multidisciplinary curriculum comprises four

Review of preliminary additional heating experiments in JT-60 (Aug. - Nov., 1986)

International Nuclear Information System (INIS)

1987-03-01

This is a prompt report on preliminary additional heating experiments in JT-60 from August to November in 1986. Neutral beam heating power was raised up to 20 MW in about a month. Plasma stored energy is about 2 MJ and energy confinement time is 0.1 ∼ 0.12 sec with the maximum heating power. The energy confinement time shows L-mode like deterioration with power, while it has little dependence on electron density. The maximum ion temperature of ∼ 7 keV and electron temperature of 4.5 keV were obtained at relatively low electron density (n-bar e = 2 - 3 x 10 19 m -3 ). Lower hybrid wave could efficiently drive plasma current up to 1.7 MA with 1.2 MW LH power. The current drive efficiency is 1 ∼ 1.7 in ohmically heated plasmas and 2 ∼ 2.8 in NB heated plasmas. Futhermore the energy confinement was improved when neutral beam was injected into entirely current driven discharges of 1 MA by LH in contrast to inductively driven target plasmas. Similar improvement in energy confinement was observed during combined heating with NB and ion cyclotron wave. (author)

Sandia National Laboratories: CRISPR genome-editing technology

Science.gov (United States)

Environmental Management System Pollution Prevention History 60 impacts Diversity Locations Facts & Figures Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers

Sandia National Laboratories: Microsystems Science & Technology Center

Science.gov (United States)

Environmental Management System Pollution Prevention History 60 impacts Diversity Locations Facts & Figures Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers

Millennium Ecosystem Assessment: MA Rapid Land Cover Change

Data.gov (United States)

National Aeronautics and Space Administration — The Millennium Ecosystem Assessment: MA Rapid Land Cover Change provides data and information on global and regional land cover change in raster format for...

Agrobacterium-mediated transient MaFT expression in mulberry (Morus alba L.) leaves.

Science.gov (United States)

Wu, Su-Li; Yang, Xiao-Bing; Liu, Li-Qun; Jiang, Tao; Wu, Hai; Su, Chao; Qian, Yong-Hua; Jiao, Feng

2015-01-01

To optimize Agrobacterium-mediated transient transformation assay in mulberry (Morus alba L.), various infiltration methods, Agrobacterium tumefaciens (A. tumefaciens) strains, and bacterial concentrations were tested in mulberry seedlings. Compared with LBA4404, GV3101 harboring pBE2133 plasmids presented stronger GUS signals at 3 days post infiltration using syringe. Recombinant plasmids pBE2133:GFP and pBE2133:GFP:MaFT were successfully constructed. Transient expression of MaFT:GFP protein was found in leaves, petiole (cross section), and shoot apical meristem (SAM) of mulberry according to the GFP signal. Moreover, MaFT:GFP mRNA was also detected in leaves and SAM via RT-PCR and qRT-PCR. An efficient transient transformation system could be achieved in mulberry seedlings by syringe using A. tumefaciens GV3101 at the OD600 of 0.5. The movement of MaFT expression from leaves to SAM might trigger the precocious flowering of mulberry.

Laboratory septic tank performance response to electrolytic stimulation.

Science.gov (United States)

Zaveri, Rahul M; Flora, Joseph R V

2002-11-01

This research investigated the effects of electrolytic stimulation on the performance of two laboratory-scale septic tanks. The tanks were fed a synthetic solution that included cellulose, peptone trypticase, beef extract, and urea. After a baseline period with no passed current, currents ranging from 100 to 500 mA were passed through the electrodes. The chemical oxygen demand (COD) removal efficiency from the tanks improved when a current was passed, with higher removal efficiencies observed at higher levels of passed current. Hydrolytic reactions resulted in ammonia and phosphate levels in the tanks that were higher than the influent. At currents > 300 mA, these hydrolytic reactions were suppressed, resulting in phosphate levels similar to the influent and ammonia levels lower than the influent because of the settling of ammonia-containing components of the feed solution. A slight increase in nitrate levels was observed when a current was passed, indicating minimal stimulation of nitrification activity. Abiotic studies confirmed that the COD can be removed via electrolysis and the removal was proportional to the passed current. Under the conditions of this study, the primary benefit of electrolytic stimulation of the septic tank is enhanced COD removal.

Pu Denaturing by Transmutation of MA in FBR Multi-cycle

Energy Technology Data Exchange (ETDEWEB)

Meiliza, Yoshitalia; Saito, Masaki; Sagara, Hiroshi [Tokyo Institute of Technology, 2-12-1-N1-1 Ookayama, Meguro-ku, Tokyo, 1528550 (Japan)

2009-06-15

Pu accumulation and its recycling is important in the term of energy resources, however one of the most sensitive issues is non-proliferation in the future fuel cycle based on fast breeder reactor (FBR). The present paper utilizes Protected Pu Production (P{sup 3}) concept for the production of {sup 238}Pu and {sup 242}Pu by Minor Actinides (MA) transmutation to enhance the proliferation resistance of Pu in the fuel. Increase in the {sup 238}Pu and {sup 242}Pu isotopic fraction creates a high rate of internal heat generation by alpha decay (DH) and/or a high neutron source of spontaneous fission (SFN) in Pu that would be encountered during manufacturing and maintaining of nuclear explosive device. The feasibility of denaturing of Pu by MA transmutation in medium size FBR has been studied from the viewpoint of even-mass number Pu accumulation during multi-cycle of Pu and MA. The proliferation resistance property of Pu is also evaluated based on the specific decay heat and spontaneous fission neutron, compared with the reference criteria. In present paper, the P{sup 3} technology based on multi-recycled Pu and MA is compared with the conventional technology based on multi-recycled Pu only. The detail of mass balance behavior is, however, beyond the scope of the present paper. (authors)

RuleMaDrone: A Web-Interface to Visualise Space Usage Rules for Drones

OpenAIRE

Trippaers, Aäron

2015-01-01

RuleMaDrone, an application developed within this thesis, is presented as a solution to communicate the rules and regulations to drone operators. To provide the solution a framework for drone safety was designed which consists of the rules and regulations, the drone properties and the environmental factors. RuleMaDrone is developed with this framework and thus will provide drone operators with an application which they can use to find a safe and legal fly zone. RuleMaDrone u...

Identification of AR(I)MA processes for modelling temporal correlations of GPS observations

Science.gov (United States)

Luo, X.; Mayer, M.; Heck, B.

2009-04-01

In many geodetic applications observations of the Global Positioning System (GPS) are routinely processed by means of the least-squares method. However, this algorithm delivers reliable estimates of unknown parameters und realistic accuracy measures only if both the functional and stochastic models are appropriately defined within GPS data processing. One deficiency of the stochastic model used in many GPS software products consists in neglecting temporal correlations of GPS observations. In practice the knowledge of the temporal stochastic behaviour of GPS observations can be improved by analysing time series of residuals resulting from the least-squares evaluation. This paper presents an approach based on the theory of autoregressive (integrated) moving average (AR(I)MA) processes to model temporal correlations of GPS observations using time series of observation residuals. A practicable integration of AR(I)MA models in GPS data processing requires the determination of the order parameters of AR(I)MA processes at first. In case of GPS, the identification of AR(I)MA processes could be affected by various factors impacting GPS positioning results, e.g. baseline length, multipath effects, observation weighting, or weather variations. The influences of these factors on AR(I)MA identification are empirically analysed based on a large amount of representative residual time series resulting from differential GPS post-processing using 1-Hz observation data collected within the permanent SAPOS® (Satellite Positioning Service of the German State Survey) network. Both short and long time series are modelled by means of AR(I)MA processes. The final order parameters are determined based on the whole residual database; the corresponding empirical distribution functions illustrate that multipath and weather variations seem to affect the identification of AR(I)MA processes much more significantly than baseline length and observation weighting. Additionally, the modelling

Overview of engineering design, manufacturing and assembly of JT-60SA machine

Energy Technology Data Exchange (ETDEWEB)

Di Pietro, Enrico, E-mail: enrico.dipietro@jt60sa.org [JT-60SA EU Home Team, Fusion for Energy, Boltzmannstrasse 2, Garching 85748 (Germany); Barabaschi, Pietro [JT-60SA EU Home Team, Fusion for Energy, Boltzmannstrasse 2, Garching 85748 (Germany); Kamada, Yutaka [JT-60SA JA Home Team, Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan); Ishida, Shinichi [JT-60SA JA Project Team, Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan)

2014-10-15

The JT-60SA experiment is one of the three projects to be undertaken in Japan as part of the Broader Approach Agreement, conducted jointly by Europe and Japan, and complementing the construction of ITER in Europe. The JT-60SA device is a fully superconducting tokamak capable of confining break-even equivalent deuterium plasmas with equilibria covering high plasma shaping with a low aspect ratio at a maximum plasma current of I{sub p} = 5.5 MA. This makes JT-60SA capable to support and complement ITER in all the major areas of fusion plasma development necessary to decide DEMO reactor construction. After a complex start-up phase due to the necessity to carry out a re-baselining effort with the purpose to fit in the original budget while aiming to retain the machine mission, performance, and experimental flexibility, in 2009 detailed design could start. With the majority of time-critical industrial contracts in place, in 2012, it was possible to establish a credible time plan, and now, the project is progressing on schedule towards the first plasma in March 2019. After careful and focused R and D and qualification tests, the procurement of the major components and plant is now well advanced in manufacturing design and/or fabrication. In the meantime the disassembly of the JT-60U machine has been completed and the engineering of the JT-60SA assembly process has been developed. The actual assembly of JT-60SA started in January 2013 with the installation of the cryostat base. The paper gives an overview of the present status of the engineering design, manufacturing and assembly of the JT-60SA machine.

Türkiye Türkçesinde -ma Ekinin Yapım Eki Olarak İşlevleri / Functions of the Derivative Suffix -ma in Turkey Turkish

Directory of Open Access Journals (Sweden)

Nesrin Bayraktar Erten

2017-12-01

Full Text Available Abstract Functions of the suffix -ma suffix can be classified under three groups in Turkey Turkish. This suffix produces adjectives that are related with root meanings like dönme dolap, sallama çay, gömme dolap, and adjectives like bodoslama atla, silme doldur etc. Besides these functions, it produces permanent nouns like gözleme, sarma, dolma, dondurma, kuzukapama, sürme, etc. This study investigates the suffix -ma as a derivational form and its functions have been classified. The study also evaluates the frequency with which it is used to coin permanent nouns and adjectives.   Öz -ma ekinin Türkiye Türkçesinde işlevlerini başlıca üç grupta toplamak mümkündür. -ma eki ile bir yandan dönme dolap, sallama çay, gömme dolap gibi örneklerde eklendiği eylem tabanıyla ilişkili sıfatlar ve bodoslama atla, silme doldur gibi zarflar yapılırken, öte yandan da gözleme, sarma, dolma, dondurma, kuzukapama, sürme örneklerinde görüldüğü gibi kalıcı adlar yapılmıştır. Kalıcı adlar içinde yemek adları, oldukça önemli bir yer tutmaktadır. Bu çalışmada -ma eki, bir yapım eki olarak değerlendirilecek ve örnekler çerçevesinde tasnif edilerek kalıcı ad ve sıfat yapımında kullanıldığı yerlerdeki sıklık ele alınacaktır.

Produção de cidra de maçã

Directory of Open Access Journals (Sweden)

Ari de Arruda Veiga

1952-03-01

Full Text Available Diversos ensaios preliminares de vinificação do suco de maçã da variedade Ohio Beauty, cultivada em Valinhos, no Estado de São Paulo, demonstraram a viabilidade de se industrializar essa fruta e de serem obtidos principalmente diversos tipos de cidra. Trabalhando com sucos dessa variedade ácida, com um pH 2,70 em média, foram conseguidos bons tipos de cidra, que acusaram finalmente um pH = 3,60 em média. Constatou-se preferência na esterilização do suco pelo aquecimento a 65-67°C, e resfriamento a 30-35°C, antes da fermentação. Tanto a fermentação à baixa temperatura, 10-16°C, como a fermentação à temperatura ambiente, 23-28°C, deram bons resultados. O emprêgo de fermentos selecionados mostrou-se favorável à vinificação.Preliminary experiments are described on cider preparation, using the red skin Ohio Beauty apple variety cultivated at Valinhos, State of São Paulo. Starting with apple juice with a pH of 2.70, several cider types were obtained with an average pH of 3.60. Juice sterilization at temperatures of 65-67°C and subsequent lowering of temperature to 30-35°C before fermentation gave the best results. Temperature of 10-16°C as well as temperatures of 23-28°C during fermentation were used with success. Yeast strains selected for grape juice fermentation gave good results for fermentation of the apple juice here studied.

77 FR 29251 - Safety Zone; Carnival Fireworks Display, Nantasket Beach, Hull, MA

Science.gov (United States)

2012-05-17

...-AA00 Safety Zone; Carnival Fireworks Display, Nantasket Beach, Hull, MA AGENCY: Coast Guard, DHS... zone on the navigable waters off of Nantasket Beach in the vicinity of Hull, MA for a Carnival... spectators and vessels from the hazards associated with fireworks displays. Discussion of Proposed Rule Hull...

Flexibility or Inexactitude? The "Lab 60" at Karolinska Institutet: From Medical Disciplines towards the Modern Biomedical Complex.

Science.gov (United States)

Normark, Daniel

2015-05-01

In 1960, a new laboratory ("Lab 60") was built on the premises of Karolinska Institutet, Stockholm. This paper describes how the laboratory was envisioned. While planners and builders strove to optimise a generic laboratory, researchers argued for specialisation. The compromise was to enhance the reorganisation capability of the interior (flexibility) while simultaneously creating a "movable" institution consisting of researchers temporarily working in the laboratory for periods of three to five years, regardless of their disciplinary affiliation. Even though flexibility was not a novelty, the building succeeded as an organisational experiment and encouraged the abandonment of the model of one discipline, one professor, and one building in favour of a "movable" institution conducting temporary research. While the credibility of laboratories was established by their "placelessness" (anywhere), Lab 60 imitated multiple, heterogeneous sites (anything) in order to maintain credibility. As such, the lab embodied many sites between the disciplines of chemistry and medicine.

Rock et cinéma : quelques éléments sur une relation durable

OpenAIRE

Ribac, François

2006-01-01

Générique d’ouverture Le numéro de Volume ! que vous allez lire est consacré aux relations entre le rock et le cinéma. Il est publié au moment où s’ouvre la deuxième édition du Festival Paris-Cinéma. Celui-ci comprend un cycle « rock et cinéma » présenté au cinéma l’Entrepôt, à Paris, du 30 juin au 13 juillet 2004. Si l’on cherche à établir des relations entre les mondes du rock et ceux du cinéma, en voici une première illustration, puisque ce numéro est en effet coproduit par un festival de ...

Development of a high current 60 keV neutral lithium beam injector for beam emission spectroscopy measurements on fusion experiments

Science.gov (United States)

Anda, G.; Dunai, D.; Lampert, M.; Krizsanóczi, T.; Németh, J.; Bató, S.; Nam, Y. U.; Hu, G. H.; Zoletnik, S.

2018-01-01

A 60 keV neutral lithium beam system was designed and built up for beam emission spectroscopy measurement of edge plasma on the KSTAR and EAST tokamaks. The electron density profile and its fluctuation can be measured using the accelerated lithium beam-based emission spectroscopy system. A thermionic ion source was developed with a SiC heater to emit around 4-5 mA ion current from a 14 mm diameter surface. The ion optic is following the 2 step design used on other devices with small modifications to reach about 2-3 cm beam diameter in the plasma at about 4 m from the ion source. A newly developed recirculating sodium vapour neutralizer neutralizes the accelerated ion beam at around 260-280 °C even during long (manipulation techniques are applied to allow optimization, aiming, cleaning, and beam modulation. The maximum 60 keV beam energy with 4 mA ion current was successfully reached at KSTAR and at EAST. Combined with an efficient observation system, the Li-beam diagnostic enables the measurement of the density profile and fluctuations on the plasma turbulence time scale.

La zeolita y su efecto en la eficiencia del nitrógeno en arroz y maíz

Directory of Open Access Journals (Sweden)

Miguel Soca

2014-12-01

Full Text Available Este trabajo evaluó el efecto de la zeolita en las reducciones de volatilización del nitrógeno amoniacal (RVNA y volumen de lixiviados (RVL así como en rendimientos de arroz Oryza sativa L. y maíz Zea mays L. En el primer experimento bajo un Diseño Completamente al Azar (DCA se evaluó el tamaño de partícula de zeolita (< 1 mm, 1 - 2 mm, 2 - 3 mm y 3-5 mm en RVNA. El segundo experimento, consistió en evaluar RVL con la aplicación de cuatro tratamientos: testigo (T, zeolita (Z, urea (U y urea + zeolita (UZ. El tercer experimento se desarrolló en un cultivo de arroz, donde se evaluaron dos métodos de aplicación (al voleo y trasplante con cuatro tratamientos (T, U, UZ10% y UZ15% y su efecto en el rendimiento del cultivo. El cuarto experimento realizado en un campo de maíz con dos tratamientos (U y UZ15% evaluó el rendimiento del cultivo en dos suelos (aluvial y esquelético. Los tamaños de partícula entre 3 y 5 mm obtuvieron RVNA del 50% y RVL del 48%. La aplicación de zeolita en arroz obtuvo RVNA de 60% y mejoró los rendimientos sin encontrar diferencias entre método de aplicación. También su aplicación mejoró el peso de grano por mazorca y el peso seco de grano de maíz. La zeolita mejoró la eficiencia de la fertilización nitrogenada.

La fonction de la salle dans les entreprises de promotion de médiation au cinéma : mise en perspective des enjeux du numérique au regard de l’éducation au cinéma

OpenAIRE

Boutin, Perrine

2015-01-01

Si la plupart des dispositifs d’éducation au cinéma en France – comme Ecole et cinéma - considèrent encore la salle de cinéma comme un passage obligatoire, les outils numériques actuels permettent de considérer une autre pratique de la découverte du cinéma.Cette nouvelle considération est décriée par beaucoup de militants de l’éducation au cinéma, qui défendent la salle comme le « lieu naturel du cinéma ». L’article traite la question de savoir si les nouveaux outils numériques engendrent des...

Hypersomnia as presenting symptom of anti-Ma2-associated encephalitis: case study.

Science.gov (United States)

Rojas-Marcos, Iñigo; Graus, Francesc; Sanz, Gema; Robledo, Arturo; Diaz-Espejo, Carlos

2007-01-01

We describe a patient who presented with excessive daytime sleepiness (EDS) and was eventually diagnosed with anti-Ma2 encephalitis. Neurological examination disclosed somnolence, left palpebral ptosis, and vertical gaze paresis. A brain MRI showed high signal intensity in the hypothalamus and each hippocampus. Ma2 antibodies were found in the patient's serum, and fiberbronchoscopy disclosed a lung carcinoma. After three months of steroid treatment, the results of the patient's neurological exam became normal. We conclude that anti-Ma2 encephalitis may present with mostly isolated EDS and that it may respond to steroids despite old age and the presence of an untreated lung cancer.

Ma'atic Beauty: Ethics and Aesthetics of the Ancient Egyptians in Ayi ...

African Journals Online (AJOL)

... Ma'at cannot be disconnected from debates over narratives of anti-colonial and postcolonial conflicts. Indeed, Armah reveals that far from being marooned into a state of archaic, timeless and unchanging tradition, Ma'at has the potential to shape and enhance a sound and inspiring ethical code for nowadays Africans.

The irradiation as alternative treatment for laboratory wastes

International Nuclear Information System (INIS)

Borrely, Sueli Ivone; Romanelli, Maria Fernanda; Silva, Giovana Pasqualini da; Castro, Daniela Marques

2005-01-01

The irradiation of effluents may be done by electron accelerator or gamma radiation source (cobalt-60). This technology has been developed as an alternative for several contaminants from different processes and sources. This paper shows the results of electron beam applied to liquid laboratories residues (effluents and standard solutions). Radiation doses were determined for the improvement of laboratories residues measured by detoxification of them. New technologies for residues treatment as well as decreasing contaminants generation is essential part of laboratories activities for environmental management for industry, universities and research institutions. (author)

Development and tests of fast 1-MA linear transformer driver stages

Directory of Open Access Journals (Sweden)

A. A. Kim

2009-05-01

Full Text Available In this article we present the design and test results of the most powerful, fast linear transformer driver (LTD stage developed to date. This 1-MA LTD stage consists of 40 parallel RLC (resistor R, inductor L, and capacitor C circuits called “bricks” that are triggered simultaneously; it is able to deliver ∼1  MA current pulse with a rise time of ∼100  ns into the ∼0.1-Ohm matched load. The electrical behavior of the stage can be predicted by using a simple RLC circuit, thus simplifying the designing of various LTD-based accelerators. Five 1-MA LTD stages assembled in series into a module have been successfully tested with both resistive and vacuum electron-beam diode loads.

Sr isotope geochemistry of voluminous acidic pyroclastics erupted at 1-3 Ma in Northeast Japan

International Nuclear Information System (INIS)

Shirahase, Teruo; Tamanyu, Shiro; Togashi, Shigeko

1989-01-01

Sr isotope ratios are analyzed for voluminous acidic pyroclastics erupted at 1 - 3 Ma in five areas on the volcanic front of Northeast Japan. The initial values of 87 Sr/ 86 Sr ratios range from 0.7040 to 0.7055. There is no significant difference in ratios between 1 - 3 Ma acidic pyroclastics and 0 - 1 Ma andesitic volcanics in each area in spite of differences in age and in mean SiO 2 content. On the other hand, the ratios in both of 1 - 3 Ma and 0 - 1 Ma volcanics vary along arc in the same manner. The changes of Sr and Rb contents in each area are consistent with systematic changes by fractional crystallization. The low 87 Sr/ 86 Sr ratios and chemistry suggest that 1 - 3 Ma acidic pyroclastics of Northeast Japan formed by a high degree of fractional crystallization from basic magma which is common in genesis with young andesitic volcanism. The mechanisms of the formation of the basic magma and the character of mantle source in each area have not changed for the past 3 Ma. Degrees of fractional crystallization changed with changes of the tectonic condition of shallow magma chamber from a weak horizontal compression stress field to a strong one. (author)

UK laboratory intercomparison on internal dosimetry

Energy Technology Data Exchange (ETDEWEB)

Speed, J.; Birchall, A.; Bull, R.; Cockerill, R.; Jarvis, N.S.; Marsh, J.W.; Peace, M.S.; Roberts, G.; Scarlett, C.; Spencer, D.; Stewart, P

2003-07-01

A laboratory intercomparison for internal dose assessment from a variety of intake scenarios is described. This is the first UK intercomparison using the revised ICRP Human Respiratory Tract and biokinetic models. Four United Kingdom laboratories participated and six cases were assessed. Overall, the agreement in internal dose assessments between laboratories was considered satisfactory with 79% of the assessed committed effective doses, e(50), for cases within a band of {+-}40% of the median value. The range (highest/lowest) in e(50) estimated by the laboratories was smallest (1.2) for a case involving inhalation of {sup 137}Cs. The range was greatest (6.0) for a case involving a wound with, and possible inhalation of, {sup 238}Pu, {sup 239}Pu and {sup 241}Am; the variation between laboratories in assessment of intakes could not be considered to be satisfactory in this case. Judgements on the most appropriate data to use in estimating intakes, choice of parameter values for use with the ICRP models and allowing for the effects of treatment with DTPA were important sources of variability between laboratories. (author)

M&A Performance and Economic Impact: Integration and Critical Assessment of Methodological Approach

Directory of Open Access Journals (Sweden)

Karolis Andriuskevicius

2017-11-01

Full Text Available Purpose of the article: Existing methodologies employed within the M&A performance framework are investigated and critically discuss. Methodology/methods: The research has been carried out as a structured assessment of past literature. The findings from scientific articles and studies by various scholars have been categorized, grouped and summarized to discern a meta-analytic view of the work carried out to date. Scientific aim: The conducted research seeks to ascertain and evaluate theoretically existing methodologies used in empirical studies that would allow proper and critical understanding of the results of various findings in the holistic and global M&As area. Findings: The research elaborates on several key developments in M&A methodology and performance studies carried out in empirical works during the last two decades. The findings help to independently and objectively assess performance of M&A from a holistic perspective. Conclusions: Each methodology measuring either M&A performance on a corporate level or effects of M&A on the economy level shall be interpreted and relied on with caution as each of them dispose their limitations whereas application of these methodologies is subject to data availability and case specific.

Biotic Interaction in Space and Time

DEFF Research Database (Denmark)

Schmidt, Andreas Kelager

Myrmica host ants by using chemical and acoustic mimicry to coerce the ant workers to feed and nurture the caterpillar preferentially over their own brood. Maculinea alcon is thus an extreme dietary specialist as absence of just one of the hosts precludes presence of the butterfly and as a result...... further enhance the risk of extinction. Maculinea alcon is selected as an umbrella for conservation and numerous aspects of its biology has been studied extensively. This thesis explores the spatio-temporal impact of the tight biotic dependence in this tritrophic interaction system and integrates...... in host ant use as expected, and is an example of a genetic barrier operating on a temporal scale rather than spatial. In chapter II, we developed habitat suitability models for M. alcon and G. pneumonanthe potentially useful in locating undocumented populations and for improving management of them...

MaNIDA: an operational infrastructure for shipborne data

Science.gov (United States)

Macario, Ana; Scientific MaNIDA Team

2013-04-01

The Marine Network for Integrated Data Access (MaNIDA) aims to build a sustainable e-Infrastruture to support discovery and re-use of data archived in a distributed network of data providers in Germany (see related abstracts in session ESSI1.2 and session ESSI2.2). Because one of the primary focus of MaNIDA is the underway data acquired on board of German academic research vessels, we will be addressing various issues related to cruise-level metadata, shiptrack navigation, sampling events conducted during the cruise (event logs), standardization of device-related (type, name, parameters) and place-related (gazetteer) vocabularies, QA/QC procedures (near real time and post-cruise validation, corrections, quality flags) as well as ingestion and management of contextual information (e.g. various types of cruise-related reports and project-related information). One of MaNIDA's long-term goal is to be able to offer an integrative "one-stop-shop" framework for management and access of ship-related information based on international standards and interoperability. This access framework will be freely available and is intended for scientists, funding agencies and the public. The master "catalog" we are building currently contains information from 13 German academic research vessels and respective cruises (to date ~1900 cruises with expected growing rate of ~150 cruises annually). Moreover, MaNIDA's operational infrastructure will additionally provide a direct pipeline to SeaDataNet Cruise Summary Report Inventory, among others. In this presentation, we will focus on the extensions we are currently implementing to support automated acquisition and standardized transfer of various types of data from German research vessels to hosts on land. Our concept towards nationwide common QA/QC procedures for various types of underway data (including versioning concept) and common workflows will also be presented. The "linking" of cruise-related information with quality-controlled data

OVERVIEW OF THE SDSS-IV MaNGA SURVEY: MAPPING NEARBY GALAXIES AT APACHE POINT OBSERVATORY

Energy Technology Data Exchange (ETDEWEB)

Bundy, Kevin [Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), Todai Institutes for Advanced Study, the University of Tokyo, Kashiwa 277-8583 (Japan); Bershady, Matthew A.; Wake, David A.; Tremonti, Christy; Diamond-Stanic, Aleksandar M. [Department of Astronomy, University of Wisconsin-Madison, 475 North Charter Street, Madison, WI 53706 (United States); Law, David R.; Cherinka, Brian [Dunlap Institute for Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, Ontario M5S 3H4 (Canada); Yan, Renbin; Sánchez-Gallego, José R. [Department of Physics and Astronomy, University of Kentucky, 505 Rose Street, Lexington, KY 40506-0055 (United States); Drory, Niv [McDonald Observatory, Department of Astronomy, University of Texas at Austin, 1 University Station, Austin, TX 78712-0259 (United States); MacDonald, Nicholas [Department of Astronomy, Box 351580, University of Washington, Seattle, WA 98195 (United States); Weijmans, Anne-Marie [School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews KY16 9SS (United Kingdom); Thomas, Daniel; Masters, Karen; Coccato, Lodovico [Institute of Cosmology and Gravitation, University of Portsmouth, Portsmouth (United Kingdom); Aragón-Salamanca, Alfonso [School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD (United Kingdom); Avila-Reese, Vladimir [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, A.P. 70-264, 04510 Mexico D.F. (Mexico); Badenes, Carles [Department of Physics and Astronomy and Pittsburgh Particle Physics, Astrophysics and Cosmology Center (PITT PACC), University of Pittsburgh, 3941 OHara St, Pittsburgh, PA 15260 (United States); Falcón-Barroso, Jésus [Instituto de Astrofísica de Canarias, E-38200 La Laguna, Tenerife (Spain); Belfiore, Francesco [Cavendish Laboratory, University of Cambridge, 19 J. J. Thomson Avenue, Cambridge CB3 0HE (United Kingdom); and others

2015-01-01

We present an overview of a new integral field spectroscopic survey called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory), one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV) that began on 2014 July 1. MaNGA will investigate the internal kinematic structure and composition of gas and stars in an unprecedented sample of 10,000 nearby galaxies. We summarize essential characteristics of the instrument and survey design in the context of MaNGA's key science goals and present prototype observations to demonstrate MaNGA's scientific potential. MaNGA employs dithered observations with 17 fiber-bundle integral field units that vary in diameter from 12'' (19 fibers) to 32'' (127 fibers). Two dual-channel spectrographs provide simultaneous wavelength coverage over 3600-10300 Å at R ∼ 2000. With a typical integration time of 3 hr, MaNGA reaches a target r-band signal-to-noise ratio of 4-8 (Å{sup –1} per 2'' fiber) at 23 AB mag arcsec{sup –2}, which is typical for the outskirts of MaNGA galaxies. Targets are selected with M {sub *} ≳ 10{sup 9} M {sub ☉} using SDSS-I redshifts and i-band luminosity to achieve uniform radial coverage in terms of the effective radius, an approximately flat distribution in stellar mass, and a sample spanning a wide range of environments. Analysis of our prototype observations demonstrates MaNGA's ability to probe gas ionization, shed light on recent star formation and quenching, enable dynamical modeling, decompose constituent components, and map the composition of stellar populations. MaNGA's spatially resolved spectra will enable an unprecedented study of the astrophysics of nearby galaxies in the coming 6 yr.

OVERVIEW OF THE SDSS-IV MaNGA SURVEY: MAPPING NEARBY GALAXIES AT APACHE POINT OBSERVATORY

International Nuclear Information System (INIS)

Bundy, Kevin; Bershady, Matthew A.; Wake, David A.; Tremonti, Christy; Diamond-Stanic, Aleksandar M.; Law, David R.; Cherinka, Brian; Yan, Renbin; Sánchez-Gallego, José R.; Drory, Niv; MacDonald, Nicholas; Weijmans, Anne-Marie; Thomas, Daniel; Masters, Karen; Coccato, Lodovico; Aragón-Salamanca, Alfonso; Avila-Reese, Vladimir; Badenes, Carles; Falcón-Barroso, Jésus; Belfiore, Francesco

2015-01-01

We present an overview of a new integral field spectroscopic survey called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory), one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV) that began on 2014 July 1. MaNGA will investigate the internal kinematic structure and composition of gas and stars in an unprecedented sample of 10,000 nearby galaxies. We summarize essential characteristics of the instrument and survey design in the context of MaNGA's key science goals and present prototype observations to demonstrate MaNGA's scientific potential. MaNGA employs dithered observations with 17 fiber-bundle integral field units that vary in diameter from 12'' (19 fibers) to 32'' (127 fibers). Two dual-channel spectrographs provide simultaneous wavelength coverage over 3600-10300 Å at R ∼ 2000. With a typical integration time of 3 hr, MaNGA reaches a target r-band signal-to-noise ratio of 4-8 (Å –1 per 2'' fiber) at 23 AB mag arcsec –2 , which is typical for the outskirts of MaNGA galaxies. Targets are selected with M * ≳ 10 9 M ☉ using SDSS-I redshifts and i-band luminosity to achieve uniform radial coverage in terms of the effective radius, an approximately flat distribution in stellar mass, and a sample spanning a wide range of environments. Analysis of our prototype observations demonstrates MaNGA's ability to probe gas ionization, shed light on recent star formation and quenching, enable dynamical modeling, decompose constituent components, and map the composition of stellar populations. MaNGA's spatially resolved spectra will enable an unprecedented study of the astrophysics of nearby galaxies in the coming 6 yr

European Master's Program in Gerontology (EuMaG): Goals, Curriculum, and Students

Science.gov (United States)

Aartsen, Marja

2011-01-01

The European Master's Program in Gerontology (EuMaG) started in September 2003 with support from the European Commission. The EuMaG is a modular, 2-year, part-time international training program about the aging process and its societal implications. The multidisciplinary curriculum comprises four domains of gerontology (i.e., social gerontology,…

Second primary tumor in anti-Ma1/2-positive paraneoplastic limbic encephalitis.

Science.gov (United States)

Leyhe, T; Schüle, R; Schwärzler, F; Gasser, T; Haarmeier, T

2006-05-01

Memory loss can be a symptom of paraneoplastic limbic encephalitis (PLE) a neuropsychiatric disorder associated mostly with small-cell lung cancer and anti-Hu antibodies or with testicular tumors and anti-Ma2 antibodies. We present the case of a patient with temporal coincidence of beginning cognitive decline and diagnosis of a carcinoma of the prostate in whom we diagnosed anti-Ma1/Ma2-positive PLE. The tumor had been completely resected but memory impairment further deteriorated. As the effective treatment of the cancer is considered as the most efficient treatment of a paraneoplastic neurological syndrome (PNS) a second neoplasia was suspected in the patient. By the aid of whole body positron emission tomography with 18-fluorine fluoro-2-deoxy-glucose (FDG-PET) an adenocarcinoma of the cecum could be detected. Two months after surgery anti-Ma antibodies were negative. We conclude that a second neoplasia should be considered, if effective cancer treatment does not lead to improvement or stabilisation of a PNS. Tumor search should be exhaustive and include PET when conventional imaging fails to show a malignancy.

Laboratory/industry partnerships for environmental remediation

International Nuclear Information System (INIS)

Beskid, N.J.; Zussman, S.K.

1994-01-01

There are two measures of ''successful'' technology transfer in DOE's environmental restoration and waste management program. The first is remediation of DOE sites, and the second is commercialization of an environmental remediation process or product. The ideal case merges these two in laboratory/industry partnerships for environmental remediation. The elements to be discussed in terms of their effectiveness in aiding technology transfer include: a decision-making champion; timely and sufficient funding; well organized technology transfer function; well defined DOE and commercial markets; and industry/commercial partnering. Several case studies are presented, including the successful commercialization of a process for vitrification of low-level radioactive waste, the commercial marketing of software for hazardous waste characterization, and the application of a monitoring technique that has won a prestigious technical award. Case studies will include: vitrification of low-level radioactive waste (GTS Duratek, Columbia, MD); borehole liner for emplacing instrumentation and sampling groundwater (Science and Engineering Associates, Inc., Santa Fe, NM); electronic cone penetrometer (Applied Research Associates, Inc., South Royalton, VT); and software for hazardous waste monitoring ConSolve, Inc. (Lexington, MA). The roles of the Department of Energy and Argonne National Laboratory in these successes will be characterized

SiMA: A simplified migration assay for analyzing neutrophil migration.

Science.gov (United States)

Weckmann, Markus; Becker, Tim; Nissen, Gyde; Pech, Martin; Kopp, Matthias V

2017-07-01

In lung inflammation, neutrophils are the first leukocytes migrating to an inflammatory site, eliminating pathogens by multiple mechanisms. The term "migration" describes several stages of neutrophil movement to reach the site of inflammation, of which the passage of the interstitium and basal membrane of the airway are necessary to reach the site of bronchial inflammation. Currently, several methods exist (e.g., Boyden Chamber, under-agarose assay, or microfluidic systems) to assess neutrophil mobility. However, these methods do not allow for parameterization on single cell level, that is, the individual neutrophil pathway analysis is still considered challenging. This study sought to develop a simplified yet flexible method to monitor and quantify neutrophil chemotaxis by utilizing commercially available tissue culture hardware, simple video microscopic equipment and highly standardized tracking. A chemotaxis 3D µ-slide (IBIDI) was used with different chemoattractants [interleukin-8 (IL-8), fMLP, and Leukotriene B4 (LTB 4 )] to attract neutrophils in different matrices like Fibronectin (FN) or human placental matrix. Migration was recorded for 60 min using phase contrast microscopy with an EVOS ® FL Cell Imaging System. The images were normalized and texture based image segmentation was used to generate neutrophil trajectories. Based on these spatio-temporal information a comprehensive parameter set is extracted from each time series describing the neutrophils motility, including velocity and directness and neutrophil chemotaxis. To characterize the latter one, a sector analysis was employed enabling the quantification of the neutrophils response to the chemoattractant. Using this hard- and software framework we were able to identify typical migration profiles of the chemoattractants IL-8, fMLP, and LTB 4 , the effect of the matrices FN versus HEM as well as the response to different medications (Prednisolone). Additionally, a comparison of four asthmatic and

Knowledge, attitude and practice of aspects of laboratory safety in Pathology Laboratories at the University of Port Harcourt Teaching Hospital, Nigeria.

Science.gov (United States)

Ejilemele, A A; Ojule, A C

2005-12-01

To assess current knowledge, attitudes and practice of aspects of laboratory safety in pathology laboratories at the University of Port Harcourt Teaching Hospital in view of perceived inadequacies in safety practices in clinical laboratories in developing countries. Sixty (60) self- administered questionnaires were distributed to all cadres of staff in four (4) different laboratories (Chemical Pathology, Haematology, Blood bank and Medical Microbiology) at the Hospital. Gross deficiencies were found in the knowledge, attitudes and practice of laboratory safety by laboratory staff in areas of use of personal protective equipment, specimen collection and processing, centrifuge--related hazards, infective hazards waste disposal and provision and use of First Aid Kits. Issues pertaining to laboratory safety are not yet given adequate attention by both employers and employees in developing countries in this ear of resurgence of diseases such as HIV/AIDS and Hepatitis Band C, is emphasized.

46 CFR 308.521 - Application for Open Cargo Policy, Form MA-301.

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Application for Open Cargo Policy, Form MA-301. 308.521... RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.521 Application for Open Cargo Policy, Form MA-301. The standard form of application for a War Risk Open Cargo Policy...

Volcanism at 1.45 Ma within the Yellowstone Volcanic Field, United States

Science.gov (United States)

Rivera, Tiffany A.; Furlong, Ryan; Vincent, Jaime; Gardiner, Stephanie; Jicha, Brian R.; Schmitz, Mark D.; Lippert, Peter C.

2018-05-01

Rhyolitic volcanism in the Yellowstone Volcanic Field has spanned over two million years and consisted of both explosive caldera-forming eruptions and smaller effusive flows and domes. Effusive eruptions have been documented preceding and following caldera-forming eruptions, however the temporal and petrogenetic relationships of these magmas to the caldera-forming eruptions are relatively unknown. Here we present new 40Ar/39Ar dates for four small-volume eruptions located on the western rim of the second-cycle caldera, the source of the 1.300 ± 0.001 Ma Mesa Falls Tuff. We supplement our new eruption ages with whole rock major and trace element chemistry, Pb isotopic ratios of feldspar, and paleomagnetic and rock magnetic analyses. Eruption ages for the effusive Green Canyon Flow (1.299 ± 0.002 Ma) and Moonshine Mountain Dome (1.302 ± 0.003 Ma) are in close temporal proximity to the eruption age of the Mesa Falls Tuff. In contrast, our results indicate a period of volcanism at ca 1.45 Ma within the Yellowstone Volcanic Field, including the eruption of the Bishop Mountain Flow (1.458 ± 0.002 Ma) and Tuff of Lyle Spring (1.450 ± 0.003 Ma). These high-silica rhyolites are chemically and isotopically distinct from the Mesa Falls Tuff and related 1.3 Ma effusive eruptions. The 40Ar/39Ar data from the Tuff of Lyle Spring demonstrate significant antecrystic inheritance, prevalent within the upper welded ash-flow tuff matrix, and minimal within individual pumice. Antecrysts are up to 20 kyr older than the eruption, with subpopulations of grains occurring every few thousand years. We interpret these results as an indicator for the timing of magmatic pulses into a growing magmatic system that would ultimately erupt the Tuff of Lyle Spring, and which we more broadly interpret as the tempo of crustal accumulation associated with bimodal magmatism. We propose a system whereby chemically, isotopically, and temporally distinct, isolated small-volume magma batches are

Experience of steam generator tube examination in the hot laboratory of EDF: analysis of recent events concerning the secondary side

International Nuclear Information System (INIS)

Thebault, Y.; Bouvier, O. de; Boccanfuso, M.; Coquio, N.; Barbe, V.; Molinie, E.

2011-01-01

Until 2010, more than 60 steam generator (SG) tubes have been removed and analysed in the EDF hot laboratory of CEIDRE/Chinon. This article is particularly related to three recent events that lead to the extraction of several tubes dedicated to laboratory destructive examinations. The first event that constitutes a first occurrence on the EDF Park, concerns the detection of a circumferential crack on the external surface of a tube located at tube support plate elevation. After this observation, several tubes have been extracted from Bugey 3 and Fessenheim 2 nuclear power plants with steam generators equipped with 600 MA bundle. The other two events concern the consequences of chemical cleaning of the tube bundle steam generators. The examples chosen are from Cruas 4 et Chinon B2 units whose tubes were extracted following non destructive testing performed immediately after or at the completion of cycle following the chemical cleaning. In the case of Cruas 4, Eddy Current Testing (ET) were performed for requalification of steam Generators after chemical cleaning. They allowed the detection of an indication located at the bottom of tube for a large number of tubes; the ET signal was similar to that corresponding to 'deposit' corrosion. Moreover, inspections of Chinon-B2 SGs at the end of the operation cycle following the chemical cleaning, showed the presence of conductor deposits at the bottom of some tubes. The first part of this document presents the major results of laboratory examinations of the pulled tubes of Bugey 3 and Fessenheim 2 and their analysis. Hypothesis concerning damage mechanisms of the tubes are also proposed. The second part of the paper relates the results of the laboratory examinations of the pulled tubes of Cruas 4 and Chinon B 2 after chemical cleaning and their analysis. (authors)

Numerical simulation of a high-brightness lithium ion gun for a Zeeman polarimetry on JT-60U

International Nuclear Information System (INIS)

Kojima, Atsushi; Kamiya, Kensaku; Fujita, Takaaki; Kamada, Yutaka; Iguchi, Harukazu

2007-01-01

A lithium ion gun is under construction for a lithium beam Zeeman polarimetry on JT-60U. The performance of the prototype ion gun has been estimated by the numerical simulation taking the space charge effects into account. The target values of the ion gun are the beam energy of 30 keV, the beam current of 10 mA and the beam divergence angle within 0.13 degrees. The low divergence of 0.13 degrees is required for the geometry of the Zeeman polarimetry on JT-60U where the observation area is 6.5 m away from the neutralizer. The numerical simulation needs to be carried out for the design study because the requirement of the divergence angle is severe for the development of the high-brightness ion gun. The simulation results show the beam loss of 50% caused by the clash to the electrode such as the cathode and the neutralizer. Moreover, the beam transport efficiency from the neutralizer to the observation area is low due to the broadening of the divergence angle. The total beam efficiency is about 5%. Extracted beam profile affects the beam focusing and the efficiency. The peaked profile achieves better efficiency than the hollow one. As a result, beam current of 1 mA is obtained at the observation area by the simulation for the prototype ion gun. (author)

Caractérisation des systemes de production à base de maïs dans ...

African Journals Online (AJOL)

La présente recherche vise à caractériser les systèmes de production à base de maïs au Bénin pour un appui-conseil ciblé aux producteurs de maïs. La base de sondage est la base de données du sous-projet "Centre National de Spécialisation sur le Maïs", exécuté par l'Institut National des Recherches Agricoles du Bénin ...

Aileler, Öğretmenler ve Dil ve Konuşma Terapistlerinin Çocuklardaki Dil ve Konuşma Bozukluklarına Yönelik Tutum ve Bilgilerinin Değerlendirilmesi

Directory of Open Access Journals (Sweden)

Bülent TOĞRAM

2015-12-01

Full Text Available Çocuklardaki iletişim sorunları aile bildirimleri, öğretmen raporları ve dil ve konuşma terapistleri (DKT tarafından yapılan değerlendirmeler ile saptanmaktadır. Dil ve konuşma bozukluklarının önlenmesi ve terapisinde işbirliği içinde bulunmaları gereken bu üçlü grubun konuya ilişkin görüş ve tutumları alanyazında önemli bulunmaktadır. Bu çalışmanın amacı, ebeveynlerin, öğretmenlerin ve DKT’lerin dil ve konuşma bozuklukları alanındaki sorumluluk ve rollerini nasıl algıladıklarını, dil ve konuşma bozukluğu olan çocuğun akademik ve sosyal başarısına yönelik tutumlarını, dil ve konuşma bozukluklarının nedenleri ve terapisine yönelik düşüncelerini betimlemektir. Çalışmaya 37 aile bireyi, 46 öğretmen ve 35 DKT katılmıştır. Anket yoluyla elde edilen veriler her grubun konuya ilişkin bilgisini ortaya koymak için karşılaştırılmıştır. Dil ve konuşma bozukluğu olan çocukların akademik/sosyal başarılarına yönelik tutumlarında diğer katılımcı gruplara göre öğretmenlerin, çocukların terapi gereksinimlerine yönelik tutumlarında ise ailelerin daha kararsız tutumlar geliştirdikleri dikkat çekmektedir.Dil ve konuşma bozukluklarının nedenleri ve terapi eksikliklerine yönelik bilgilerinde grupların öncelikli sıralamalarının farklılaştığı görülmüştür

Neutron radiographic characteristics of MA-ND type (allyl-diglycol-carbonate) nuclear track detectors

Energy Technology Data Exchange (ETDEWEB)

Ilic, R.; Rant, J.; Humar, M.; Somogyi, G.; Hunyadi, I.

1986-01-01

Neutron radiographic properties of recently developed new nuclear track detectors (MA-ND/..cap alpha.., MA-ND/p and MA-ND/p1), manufactured from allyl diglycol carbonate, were studied. It was found that the quality of radiographic image has an optimum at a removed layer thickness of about 0.8 ..mu..m. The image obtained under this condition is characterized by high detection sensitivity to neutrons (approx. 8.10/sup -3/ tracks/nsub(th) when using B converter) and by excellent inherent unsharpness (approx. 5 ..mu..m) as well as high image contrast (maximum value of net optical density is approx. 1.4).

Analysis of Three UH-60 Blackhawk Servolink Components P/N 70400-08110-061

National Research Council Canada - National Science Library

Pepi, Marc

2002-01-01

The Processing and Properties Branch of the U.S. Army Research Laboratory's (ARL) Weapons and Materials Research Directorate examined the shot-peened surfaces of three UH-60 Blackhawk utility helicopter servolinks...

Refractive results of cataract surgery using optical biometry and Haigis formula in eyes with refractive keratotomy

Directory of Open Access Journals (Sweden)

Juan Carlos Sánchez Caballero

2013-04-01

Full Text Available OBJECTIVE: To analyze refractive results in postoperative cataract surgery in eyes previously submitted to keratotomy using Haigis formula and data provided by IOL Master®optical biometer. METHODS: The measurements for IOL calculation were obtained through optical biometry by partial coherence interferometry (IOL Master®- Zeiss, 5.4 and 5.5 version that provides us with the axial length, the central keratometry of 2.5mm, white-to-white diameter and anterior chamber anatomical depth. The formula chosen was Haigis. The surgical technique applied was with the scleral incision at 1.5 mm from the limbus, with scleral-corneal tunnel of 2.2 mm wide, phacoemulsification using INFINITI Ozil®- Alcon and implantation of hydrophobic acrylic aspheric intraocular lens - SN60WF®- Alcon. RESULTS: We studied 20 eyes submitted to keratotomy in the past and currently with cataract with indication for cataract surgerywith intraocular lens implantation using phacoemulsification. Postoperative spherical equivalent was plano in 40% of the eyes and lower than -1.00 in 85% of the eyes. CONCLUSION: The optical biometry by partial coherence interferometry associated with Haigis formula is a valid alternative in IOL calculation for eyes submitted to keratotomy. The refractive results are highly predictable and reproducible.

46 CFR 308.409 - Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283.

Science.gov (United States)

2010-10-01

... Policy, Form MA-283. 308.409 Section 308.409 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF... of War Risk Builder's Risk Insurance Policy, Form MA-283. The standard form of War Risk Builder's Risk Insurance Policy, Form MA-283 may be obtained from the American War Risk Agency or MARAD. ...

Industrial chains and innovation activity in Małopolska region in 2008-2010

Directory of Open Access Journals (Sweden)

Świadek Arkadiusz

2014-05-01

Full Text Available Znaczenie powiązań przemysłowych dla aktywności innowacyjnej przedsiębiorstw w regionie małopolskim w latach 2008-2010 Głównym celem prowadzonych badań była próba poszukiwania zmiennych warunków wpływu łańcuchów dostaw na działalność innowacyjną przedsiębiorstw w obrębie wybranego regionalnego systemu przemysłowego, a tym samym określenie warunków brzegowych dla modelu regionalnej sieci innowacji, biorąc pod uwagę specyfikę województwa małopolskiego. Badanie zostało oparte na kwestionariuszu ankietowym i wykonane na grupie 500 firm z Małopolski. W badaniu wykorzystano modelowanie probitowe. Metoda ta jest skutecznym narzędziem analizy dużych, ale statycznych prób, w których zmienna zależna ma charakter jakościowy.

CULTURAL DUE DILIGENCE IN M&A. IMPORTANCE OF SOFT RISKS FACTORS

Directory of Open Access Journals (Sweden)

Iulian Walter

2017-07-01

Full Text Available During the last decades, the corporate world has witnessed a significant rise in the number of cross border mergers and acquisitions (M&As. In cross border M&As, not only different corporate cultures collide, but also different professional and national cultures. The purpose of Cultural Due Diligence (CDD is to get a coherent image of the intercultural challenges of the M&A in order to be aware of the intercultural risks and opportunities. This article aims to reveal the perception of managers involved in the pre-M&A stage on the soft risks factors that need to be investigated during CDD. This study proposes an appraisal of the most important intercultural issues that need to be considered in M&A. Our contribution to the intercultural aspects of M&A literature consists in improving the current understanding of Cultural Due Diligence content.

CULTURAL DUE DILIGENCE IN M&A. IMPORTANCE OF SOFT RISKS FACTORS

Directory of Open Access Journals (Sweden)

Iulian Warter

2017-06-01

Full Text Available During the last decades, the corporate world has witnessed a significant rise in the number of cross border mergers and acquisitions (M&As. In cross border M&As, not only different corporate cultures collide, but also different professional and national cultures. The purpose of Cultural Due Diligence (CDD is to get a coherent image of the intercultural challenges of the M&A in order to be aware of the intercultural risks and opportunities. This article aims to reveal the perception of managers involved in the pre-M&A stage on the soft risks factors that need to be investigated during CDD. This study proposes an appraisal of the most important intercultural issues that need to be considered in M&A. Our contribution to the intercultural aspects of M&A literature consists in improving the current understanding of Cultural Due Diligence content.

Le cinéma comme articulation des différences culturelles : une approche post-coloniale du cinéma brésilien

OpenAIRE

César, Amaranta

2013-01-01

Les concepts d’identité et de nation sont des paradigmes analytiques et critiques qui ont forgé d’importants mouvements cinématographiques comme le Cinema Novo. Le cinéma brésilien est par conséquent un cinéma en recherche de son identité artistique et politique. Mais une telle quête est vouée à l’échec si l’on considère la crise du concept de nation et le renouveau de la notion d’identité. C’est pourquoi je suggère de développer un modèle analytique sur la façon dont les films construisent d...

Channel of Axial Injection of DC-60 Cyclotron

CERN Document Server

Gikal, B N; Bogomolov, S L; Borisenko, A N; Borisov, O N; Gulbekyan, G G; Ivanenko, I A; Kalagin, I V; Kazacha, V I; Kazarinov, N Yu; Khabarov, M V; Lysukhin, S N; Melnikov, V N; Paschenko, S V; Tikhomirov, A V

2006-01-01

The design study and realization of the axial injection beam line of DC-60 cyclotron constructed at the Flerov Laboratory of Nuclear Reactions of the Joint Institute for Nuclear Research are given. The channel allows one to transport and to inject into the cyclotron ions with mass-to-charge ratio $A/Z$ being within interval A/Z=6-12 and kinetic energy up to 17 $Z/A$ keV/m.u.

SDSS-IV/MaNGA: SPECTROPHOTOMETRIC CALIBRATION TECHNIQUE

Energy Technology Data Exchange (ETDEWEB)

Yan, Renbin; Sánchez-Gallego, José R. [Department of Physics and Astronomy, University of Kentucky, 505 Rose St., Lexington, KY 40506-0057 (United States); Tremonti, Christy; Bershady, Matthew A.; Eigenbrot, Arthur; Wake, David A. [Department of Astronomy, University of Winsconsin-Madison, 475 N. Charter Street, Madison, WI 53706-1582 (United States); Law, David R. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Schlegel, David J. [Physics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720-8160 (United States); Bundy, Kevin [Kavli IPMU (WPI), UTIAS, The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Drory, Niv [McDonald Observatory, Department of Astronomy, University of Texas at Austin, 1 University Station, Austin, TX 78712-0259 (United States); MacDonald, Nicholas [Department of Astronomy, Box 351580, University of Washington, Seattle, WA 98195 (United States); Bizyaev, Dmitry [Apache Point Observatory, P.O. Box 59, sunspot, NM 88349 (United States); Blanc, Guillermo A. [Departamento de Astronomía, Universidad de Chile, Camino el Observatorio 1515, Las Condes, Santiago (Chile); Blanton, Michael R.; Hogg, David W. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Cherinka, Brian [Dunlap Institute for Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, Ontario M5S 3H4 (Canada); Gunn, James E. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Harding, Paul [Department of Astronomy, Case Western Reserve University, Cleveland, OH 44106 (United States); Sánchez, Sebastian F., E-mail: yanrenbin@uky.edu [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, A.P. 70-264, 04510 Mexico D.F. (Mexico); and others

2016-01-15

Mapping Nearby Galaxies at Apache Point Observatory (MaNGA), one of three core programs in the Sloan Digital Sky Survey-IV, is an integral-field spectroscopic survey of roughly 10,000 nearby galaxies. It employs dithered observations using 17 hexagonal bundles of 2″ fibers to obtain resolved spectroscopy over a wide wavelength range of 3600–10300 Å. To map the internal variations within each galaxy, we need to perform accurate spectral surface photometry, which is to calibrate the specific intensity at every spatial location sampled by each individual aperture element of the integral field unit. The calibration must correct only for the flux loss due to atmospheric throughput and the instrument response, but not for losses due to the finite geometry of the fiber aperture. This requires the use of standard star measurements to strictly separate these two flux loss factors (throughput versus geometry), a difficult challenge with standard single-fiber spectroscopy techniques due to various practical limitations. Therefore, we developed a technique for spectral surface photometry using multiple small fiber-bundles targeting standard stars simultaneously with galaxy observations. We discuss the principles of our approach and how they compare to previous efforts, and we demonstrate the precision and accuracy achieved. MaNGA's relative calibration between the wavelengths of Hα and Hβ has an rms of 1.7%, while that between [N ii] λ6583 and [O ii] λ3727 has an rms of 4.7%. Using extinction-corrected star formation rates and gas-phase metallicities as an illustration, this level of precision guarantees that flux calibration errors will be sub-dominant when estimating these quantities. The absolute calibration is better than 5% for more than 89% of MaNGA's wavelength range.

SDSS-IV/MaNGA: SPECTROPHOTOMETRIC CALIBRATION TECHNIQUE

International Nuclear Information System (INIS)

Yan, Renbin; Sánchez-Gallego, José R.; Tremonti, Christy; Bershady, Matthew A.; Eigenbrot, Arthur; Wake, David A.; Law, David R.; Schlegel, David J.; Bundy, Kevin; Drory, Niv; MacDonald, Nicholas; Bizyaev, Dmitry; Blanc, Guillermo A.; Blanton, Michael R.; Hogg, David W.; Cherinka, Brian; Gunn, James E.; Harding, Paul; Sánchez, Sebastian F.

2016-01-01

Mapping Nearby Galaxies at Apache Point Observatory (MaNGA), one of three core programs in the Sloan Digital Sky Survey-IV, is an integral-field spectroscopic survey of roughly 10,000 nearby galaxies. It employs dithered observations using 17 hexagonal bundles of 2″ fibers to obtain resolved spectroscopy over a wide wavelength range of 3600–10300 Å. To map the internal variations within each galaxy, we need to perform accurate spectral surface photometry, which is to calibrate the specific intensity at every spatial location sampled by each individual aperture element of the integral field unit. The calibration must correct only for the flux loss due to atmospheric throughput and the instrument response, but not for losses due to the finite geometry of the fiber aperture. This requires the use of standard star measurements to strictly separate these two flux loss factors (throughput versus geometry), a difficult challenge with standard single-fiber spectroscopy techniques due to various practical limitations. Therefore, we developed a technique for spectral surface photometry using multiple small fiber-bundles targeting standard stars simultaneously with galaxy observations. We discuss the principles of our approach and how they compare to previous efforts, and we demonstrate the precision and accuracy achieved. MaNGA's relative calibration between the wavelengths of Hα and Hβ has an rms of 1.7%, while that between [N ii] λ6583 and [O ii] λ3727 has an rms of 4.7%. Using extinction-corrected star formation rates and gas-phase metallicities as an illustration, this level of precision guarantees that flux calibration errors will be sub-dominant when estimating these quantities. The absolute calibration is better than 5% for more than 89% of MaNGA's wavelength range

Effect of gala apples (Malus domestica Borkh on lipidemia of hyperlipidemic rats Efeito da maçã gala (Malus domestica Borkh na lipidemia de ratos hipercolesterolêmicos

Directory of Open Access Journals (Sweden)

Jocelem Mastrodi Salgado

2008-06-01

style, over time, could prevent or reduce the risk of heart disease.Um estilo de vida saudável e uma dieta balanceada, associados com uma alta ingestão de frutas e vegetais estão ligados também à boa saúde e a prevenção de doenças. Maçãs contêm compostos bioativos que ajudam à prevenção e controle da hiperlipidemia. Uma das preocupações da Saúde Pública no Brasil é reduzir as doenças cardiovasculares. Assim, o objetivo deste trabalho foi analisar a composição química da maçã Gala e estudar o efeito do seu consumo no ganho de peso, comida ingerida, níveis sanguíneos de colesterol total, HDL-C, LDL-C, triglicérides, colesterol hepático e colesterol fecal em ratos albinos Wistar, alimentados com uma dieta hipercolesterolêmica. Foram utilizados seis animais para cada tratamento (controle, 5, 15, e 25% dieta de maçã, durante 30 e 60 dias. Este estudo mostrou que uma maçã (200 g pode contribuir com 14,5% do total de fibras e 55% da vitamina C recomendados, além de suprir consideráveis quantidades de produtos fenólicos (0,38 g .100 g-1 e taninos (0,16 g .100 g-1. Todos os animais mostraram uma redução não significativa no ganho de peso e ingestão de comida com o aumento na quantidade de maçã na sua dieta. Ao final de 30 dias, todas as dietas resultaram em uma redução significativa de triglicérides comparados ao grupo controle. As dietas de 15 e 25% mostraram redução significativa nos níveis séricos de colesterol total e LDL-C e um aumento nos níveis fecais de colesterol em relação ao grupo controle. A dieta de 25% de maçã resultou em uma significativa redução dos níveis de colesterol hepático comparados com o grupo controle. Depois de 60 dias, os níveis séricos de colesterol total, LDL-C, HDL-C e triglicérides em ratos alimentados com 5, 15 e 25% de dieta de maçã eram similares ao grupo controle. Isto, provavelmente foi devido a uma reversão do processo. Estes resultados mostram a importância da maçã Gala no

Anti-Ma-associated encephalitis due to dysgerminoma in a woman with Swyer syndrome.

Science.gov (United States)

Al-Thubaiti, Ibtisam; Al-Hayek, Kefah; Binfalah, Mohammed

2013-04-09

Paraneoplastic limbic encephalitis (PLE)/diencephalitis associated with anti-Ma2 antibodies was linked to testicular cancer and non-small-cell lung cancer (non-SCLC).(1,2) We report a case of anti-Ma-associated PLE/diencephalitis due to dysgerminoma in a woman with gonadal dysgenesis, or Swyer syndrome.

Hanford External Dosimetry Technical Basis Manual PNL-MA-842

Energy Technology Data Exchange (ETDEWEB)

Rathbone, Bruce A.

2010-04-01

The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at the U.S. Department of Energy (DOE) Hanford site. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with requirements of 10 CFR 835, the DOE Laboratory Accreditation Program, the DOE Richland Operations Office, DOE Office of River Protection, DOE Pacific Northwest Office of Science, and Hanford’s DOE contractors. The dosimetry system is operated by the Pacific Northwest National Laboratory (PNNL) Hanford External Dosimetry Program which provides dosimetry services to PNNL and all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision

Hanford External Dosimetry Technical Basis Manual PNL-MA-842

Energy Technology Data Exchange (ETDEWEB)

Rathbone, Bruce A.

2011-04-04

The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at the U.S. Department of Energy (DOE) Hanford site. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with requirements of 10 CFR 835, the DOE Laboratory Accreditation Program, the DOE Richland Operations Office, DOE Office of River Protection, DOE Pacific Northwest Office of Science, and Hanford’s DOE contractors. The dosimetry system is operated by the Pacific Northwest National Laboratory (PNNL) Hanford External Dosimetry Program which provides dosimetry services to PNNL and all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision

The GSF secondary standard dosimetry laboratory for photon and beta radiation

International Nuclear Information System (INIS)

Eckerl, H.; Nahrstedt, U.

1986-03-01

A brief outline of the laboratory's tasks and a detailed description of its layout and equipment is given. The laboratory contains a Co-60 irradiation unit, a Cs-137 irradiation unit, a panoramic irradiation unit for different nuclide sources, a 160- and 420 kV X-ray unit, a beta-irradiation unit and a measuring and control room. The calibration laboratory is equipped with reference and field dosemeters. (DG)

Relative contributions of food and water in the accumulation of 60Co by a freshwater fish

International Nuclear Information System (INIS)

Baudin, J.P.; Fritsch, A.F.

1989-01-01

Because of its presence in the natural environment a laboratory research program was undertaken with 60 Co, focused on a freshwater fish, Cyprinus carpio. In this paper results from laboratory experiments conducted to assess the role of food and water in the uptake and retention of 60 Co by the carp are reported. The 60 Co accumulation by the fish from water, from food and from both sources simultaneously were studied during the first phase. After this exposure phase the individuals are transferred to non-radioactive water and/or received unlabelled food to follow depuration of the radionuclide. There was no significant difference between the fish of the 3 treatment groups; the greatest fraction of residual radiocobalt resided in digestive tract that accounted for 20-25% of the total 69 Co body burden. (author)

Reification without Evaluation.

Science.gov (United States)

1988-06-01

PROJECT. TASK Artificial Inteligence Laboratory AREA & WORK UNIT NuMBERS ’’ 545 Technology Square 0 Cambridge, MA 02139 L $I 1, CONTROLLINO OFFICE NAME...7RD-ft" 28 REIFICRIO WITHOUT EYRURTION(U) rASSACHUSETTS INST OF 1/:LTECH CUZDGE ARTIFICI L INTELLIGENCE LUN R MEN JUN 60 RI-M-946 NM14-5-K-0-0124...themselves. This report, describes research done at, tie Artificial Intelligence Laboratory of the Massachusetts Institute of Technology. Support for the

The Data Reduction Pipeline for the SDSS-IV MaNGA IFU Galaxy Survey

Science.gov (United States)

Law, David R.; Cherinka, Brian; Yan, Renbin; Andrews, Brett H.; Bershady, Matthew A.; Bizyaev, Dmitry; Blanc, Guillermo A.; Blanton, Michael R.; Bolton, Adam S.; Brownstein, Joel R.; Bundy, Kevin; Chen, Yanmei; Drory, Niv; D'Souza, Richard; Fu, Hai; Jones, Amy; Kauffmann, Guinevere; MacDonald, Nicholas; Masters, Karen L.; Newman, Jeffrey A.; Parejko, John K.; Sánchez-Gallego, José R.; Sánchez, Sebastian F.; Schlegel, David J.; Thomas, Daniel; Wake, David A.; Weijmans, Anne-Marie; Westfall, Kyle B.; Zhang, Kai

2016-10-01

Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) is an optical fiber-bundle integral-field unit (IFU) spectroscopic survey that is one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV). With a spectral coverage of 3622-10354 Å and an average footprint of ˜500 arcsec2 per IFU the scientific data products derived from MaNGA will permit exploration of the internal structure of a statistically large sample of 10,000 low-redshift galaxies in unprecedented detail. Comprising 174 individually pluggable science and calibration IFUs with a near-constant data stream, MaNGA is expected to obtain ˜100 million raw-frame spectra and ˜10 million reduced galaxy spectra over the six-year lifetime of the survey. In this contribution, we describe the MaNGA Data Reduction Pipeline algorithms and centralized metadata framework that produce sky-subtracted spectrophotometrically calibrated spectra and rectified three-dimensional data cubes that combine individual dithered observations. For the 1390 galaxy data cubes released in Summer 2016 as part of SDSS-IV Data Release 13, we demonstrate that the MaNGA data have nearly Poisson-limited sky subtraction shortward of ˜8500 Å and reach a typical 10σ limiting continuum surface brightness μ = 23.5 AB arcsec-2 in a five-arcsecond-diameter aperture in the g-band. The wavelength calibration of the MaNGA data is accurate to 5 km s-1 rms, with a median spatial resolution of 2.54 arcsec FWHM (1.8 kpc at the median redshift of 0.037) and a median spectral resolution of σ = 72 km s-1.

THE DATA REDUCTION PIPELINE FOR THE SDSS-IV MaNGA IFU GALAXY SURVEY

International Nuclear Information System (INIS)

Law, David R.; Cherinka, Brian; Yan, Renbin; Andrews, Brett H.; Bershady, Matthew A.; Bizyaev, Dmitry; Blanc, Guillermo A.; Blanton, Michael R.; Bolton, Adam S.; Brownstein, Joel R.; Bundy, Kevin; Chen, Yanmei; Drory, Niv; D’Souza, Richard; Jones, Amy; Kauffmann, Guinevere; Fu, Hai

2016-01-01

Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) is an optical fiber-bundle integral-field unit (IFU) spectroscopic survey that is one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV). With a spectral coverage of 3622–10354 Å and an average footprint of ∼500 arcsec 2 per IFU the scientific data products derived from MaNGA will permit exploration of the internal structure of a statistically large sample of 10,000 low-redshift galaxies in unprecedented detail. Comprising 174 individually pluggable science and calibration IFUs with a near-constant data stream, MaNGA is expected to obtain ∼100 million raw-frame spectra and ∼10 million reduced galaxy spectra over the six-year lifetime of the survey. In this contribution, we describe the MaNGA Data Reduction Pipeline algorithms and centralized metadata framework that produce sky-subtracted spectrophotometrically calibrated spectra and rectified three-dimensional data cubes that combine individual dithered observations. For the 1390 galaxy data cubes released in Summer 2016 as part of SDSS-IV Data Release 13, we demonstrate that the MaNGA data have nearly Poisson-limited sky subtraction shortward of ∼8500 Å and reach a typical 10 σ limiting continuum surface brightness μ  = 23.5 AB arcsec −2 in a five-arcsecond-diameter aperture in the g -band. The wavelength calibration of the MaNGA data is accurate to 5 km s −1 rms, with a median spatial resolution of 2.54 arcsec FWHM (1.8 kpc at the median redshift of 0.037) and a median spectral resolution of σ  = 72 km s −1 .

6 Ma age of carving Westernmost Grand Canyon: Reconciling geologic data with combined AFT, (U-Th)/He, and 4He/3He thermochronologic data

Science.gov (United States)

Winn, Carmen; Karlstrom, Karl E.; Shuster, David L.; Kelley, Shari; Fox, Matthew

2017-09-01

Conflicting hypotheses about the timing of carving of the Grand Canyon involve either a 70 Ma (;old;) or conflict with these lines of evidence, but are reconciled in this paper via the integration of three methods of analyses on the same sample: apatite (U-Th)/He ages (AHe), 4He/3He thermochronometry (4He/3He), and apatite fission-track ages and lengths (AFT). HeFTy software was used to generate time-temperature (t-T) paths that predict all new and published 4He/3He, AHe, and AFT data to within assumed uncertainties. These t-T paths show cooling from ∼100 °C to 40-60 °C in the Laramide (70-50 Ma), long-term residence at 40-60 °C in the mid-Tertiary (50-10 Ma), and cooling to near-surface temperatures after 10 Ma, and thus support young incision of the westernmost Grand Canyon. A subset of AHe data, when interpreted alone (i.e. without 4He/3He or AFT data), are better predicted by t-T paths that cool to surface temperatures during the Laramide, consistent with an ;old; Grand Canyon. However, the combined AFT, AHe, and 4He/3He analysis of a key sample from Separation Canyon can only be reconciled by a ;young; Canyon. Additional new AFT (5 samples) and AHe data (3 samples) in several locations along the canyon corridor also support a ;young; Canyon. This inconsistency, which mimics the overall controversy of the age of the Grand Canyon, is reconciled here by optimizing cooling paths so they are most consistent with multiple thermochronometers from the same rocks. To do this, we adjusted model parameters and uncertainties to account for uncertainty in the rate of radiation damage annealing in these apatites during sedimentary burial and the resulting variations in He retentivity. In westernmost Grand Canyon, peak burial conditions (temperature and duration) during the Laramide were likely insufficient to fully anneal radiation damage that accumulated during prolonged, near-surface residence since the Proterozoic. We conclude that application of multiple

Antioxidative effects in vivo and colonization of Lactobacillus plantarum MA2 in the murine intestinal tract.

Science.gov (United States)

Tang, Wei; Xing, Zhuqing; Hu, Wei; Li, Chao; Wang, Jinju; Wang, Yanping

2016-08-01

Lactobacillus plantarum MA2 was isolated from traditional Chinese Tibet kefir grains, which possess several excellent properties and functions. We previously demonstrated the antioxidant activities of this bacterium in vitro. However, the maintenance and survival of L. plantarum MA2 inside the murine intestinal tract, where it exerts its probiotic properties, and whether its effects are elicited directly on the host remain unknown. Therefore, this study investigated the mechanisms of L. plantarum MA2 in aging mice following D-galactose administration. The levels of malondialdehyde decreased significantly in the L. plantarum MA2 groups after oral ingestion compared to the D-galactose model group, and total antioxidant capacity and glutathione peroxidase and superoxide dismutase activities increased significantly in the serum and liver. We combined fluorescein isothiocyanate labeling and green fluorescent protein expression to dynamically monitor the colonization and distribution of L. plantarum MA2 in the murine intestinal tract. The results indicated that L. plantarum MA2 was detected in the ileum, colon, and feces after single and continuous oral administration at day 21 and was maintained at 10(4)-10(5) CFU/g. These results suggest that L. plantarum MA2 colonizes and survives in the murine intestinal tract to exert its antioxidative effects.

Personal Hygiene Practices among Urban Homeless Persons in Boston, MA.

Science.gov (United States)

Leibler, Jessica H; Nguyen, Daniel D; León, Casey; Gaeta, Jessie M; Perez, Debora

2017-08-18

Persons experiencing homelessness in the United States experience significant barriers to self-care and personal hygiene, including limited access to clean showers, laundry and hand washing facilities. While the obstacles to personal hygiene associated with homelessness may increase risk of infectious disease, hygiene-related behaviors among people experiencing homelessness has received limited attention. We conducted a cross-sectional study of individuals experiencing homelessness in Boston, MA ( n = 194) to identify hygiene-related self-care practices and risk factors for reduced hygiene in this population. Most participants (72%) reported taking a daily shower. More than 60% reported hand washing with soap five or more times each day, and use of hand sanitizer was widespread (89% reported using sanitizer in the last week). A majority (86%) used a laundromat or laundry machine to wash clothing, while 14% reported washing clothing in the sink. Heavy drinking, injection drug use, and sleeping outdoors were identified as significant risk factors for reduced hygiene practices. People experiencing homelessness who also engage in these activities may be among the most difficult to reach for intervention, yet targeted efforts may decrease illness risk associated with reduced hygiene. Housed friends and family play a critical role in assisting homeless individuals maintain hygiene by providing showers and laundry facilities.

Narcolepsy, REM sleep behavior disorder, and supranuclear gaze palsy associated with Ma1 and Ma2 antibodies and tonsillar carcinoma.

Science.gov (United States)

Adams, Chris; McKeon, Andrew; Silber, Michael H; Kumar, Rajeev

2011-04-01

To describe a patient with diencephalic and mesencephalic presentation of a Ma1 and Ma2 antibody-associated paraneoplastic neurological disorder. Case report. The Colorado Neurological Institute Movement Disorders Center in Englewood, Colorado, and the Mayo Clinic in Rochester, Minnesota. A 55-year-old man with a paraneoplastic neurological disorder characterized by rapid eye movement sleep behavior disorder, narcolepsy, and a progressive supranuclear palsy-like syndrome in the setting of tonsillar carcinoma. Immunotherapy for paraneoplastic neurological disorder, surgery and radiotherapy for cancer, and symptomatic treatment for parkinsonism and sleep disorders. Polysomnography, multiple sleep latency test, and neurological examination. The cancer was detected at a limited stage and treatable. After oncological therapy and immunotherapy, symptoms stabilized. Treatment with modafinil improved daytime somnolence. Rapid onset and progression of multifocal deficits may be a clue to paraneoplastic etiology. Early treatment of a limited stage cancer (with or without immunotherapy) may possibly slow progression of neurological symptoms. Symptomatic treatment may be beneficial.

Schéma directeur des Systèmes d'information 2012-2016

OpenAIRE

Institut National de Recherche Agronomique UAR 0776 Administration du siège

2012-01-01

Le schéma directeur des systèmes d’information de l’inra est le premier Schéma directeur dont l’institut se dote dans le champ des systèmes D’information. Il couvre la période 2012‐2016 du contrat d’objectifs Et s’inscrit dans les perspectives scientifiques dressées par le document D’orientation 2010‐2020

China's Overseas M&A in Global Economic Crisis

Institute of Scientific and Technical Information of China (English)

Han Kang

2009-01-01

@@ verseas Merger and Acquisition (M&A) is not only the major means for the enterprises to expand rapid-ly and operate globally, but also the significant stra-tegic tools for acquiring advanced technotegy from other companies and seizing the market and other resources.

270 nm Pseudomorphic Ultraviolet Light-Emitting Diodes with Over 60 mW Continuous Wave Output Power

Science.gov (United States)

Grandusky, James R.; Chen, Jianfeng; Gibb, Shawn R.; Mendrick, Mark C.; Moe, Craig G.; Rodak, Lee; Garrett, Gregory A.; Wraback, Michael; Schowalter, Leo J.

2013-03-01

In this letter, the achievement of over 60 mW output power from pseudomorphic ultraviolet light-emitting diodes in continuous wave operation is reported. Die thinning and encapsulation improved the photon extraction efficiency to over 15%. Improved thermal management and a high characteristic temperature resulted in a low thermal rolloff up to 300 mA injection current with an output power of 67 mW, an external quantum efficiency (EQE) of 4.9%, and a wall plug efficiency (WPE) of 2.5% for a single-chip device emitting at 271 nm in continuous wave operation.

Konsep Pendidikan Akhlak dan Dakwah dalam Perspektif Dr. KH. Zakky Mubarak, MA

Directory of Open Access Journals (Sweden)

Muchtar Muchtar

2017-09-01

Full Text Available Research aims to understand role, and the concept of education and dakwah in perspective Dr. KH. Zakky Mubarak, MA. This research departs from looking at the phenomenon of human life is increasingly complex, entered the modern life and globalization present and the future, wich is characterized by technical and professional paced lives, is forecast to many people ignore the moral and religious in individual and social life. The concept of moral education in the perspective of Dr. KH. Zakky Mubarak, MA that establishes the character of the learners, provide good role models, develop the moral high level, and then apply the knowledge of good character and exemplary in real life so it can become an ingrained habit. The concept of dakwah in perspective Dr. KH. Zakky Mubarak, MA at least two steps that need to be understood by a preacher, first that of bringing the wisdom, it means explaining the wisdoms contained in worship and other Islamic activities without patronizing impression, meaning a preacher should put the words and appropriate sentence appropriate to the circumstances . The second is to mau'idlah hasanah , means giving advice that touch the heart so that the message can be embedded in the memories of audience. Dr. KH. Zakky Mubarak, MA is one of the Nahdlatul Ulama cleric who spend their time preaching, either through a lecture or through scientific papers, scientific papers written contains a lot of moral education that can be used as a reference.  Keywords: Concept of Education and Dakwah, Zakky Mubarak, Nahdlatul Ulama Abstrak Penelitian ini bertujuan untuk mengetahui peran, serta konsep pendidikan akhlak dan dakwah dalam perspektif Dr. KH. Zakky Mubarak, MA. Kesimpulan penelitian ini bahwa Konsep pendidikan akhlak dalam perspektif Dr. KH. Zakky Mubarak, MA yaitu menanamkan pemahaman tentang akhlak terhadap peserta didik, memberikan keteladanan yang baik, mengembangkan pada akhlak tingkat tinggi, dan kemudian mengaplikasikan

Post 4 Ma initiation of normal faulting in southern Tibet. Constraints from the Kung Co half graben

Science.gov (United States)

Mahéo, G.; Leloup, P. H.; Valli, F.; Lacassin, R.; Arnaud, N.; Paquette, J.-L.; Fernandez, A.; Haibing, L.; Farley, K. A.; Tapponnier, P.

2007-04-01

The timing of E-W extension of the Tibetan plateau provides a test of mechanical models of the geodynamic evolution of the India-Asia convergence zone. In this work we focus on the Kung Co half graben (Southern Tibet, China), bounded by an active N-S normal fault with a minimum vertical offset of 1600 m. To estimate the onset of normal faulting we combined high and medium temperature (U-Pb, Ar/Ar) and low temperature ((U-Th)/He) thermochronometry of the Kung Co pluton, a two-mica granite of the northern Himalayan granitic belt that outcrop in the footwall of the fault. Biotite and muscovite Ar/Ar ages , are close from each other [˜ 16 Ma ± 0.2 (Ms) and ˜ 15 ± 0.4 Ma (Bt)], which is typical of fast cooling. The zircon and apatite (U-Th)/He ages range from 11.3 to 9.6 Ma and 9.9 to 3.7 Ma respectively. These He ages are indicative of (1) fast initial cooling, from 11.3 to ˜ 9 Ma, gradually decreasing with time and (2) a high geothermal gradient (˜ 400 °C/km), close to the surface at ˜ 10 Ma. The Kung Co pluton was emplaced at about 22 Ma (U-Pb on zircon) at less than 10 km depth and 520-545 °C. Subsequent to its shallow emplacement, the pluton underwent fast thermal re-equilibration ending around 7.5 Ma, followed by a period of slow cooling caused either by the end of the thermal re-equilibration or by very slow exhumation (0.02-0.03 mm/yr) from ˜ 7.5 Ma to at least 4 Ma. In either case the data suggest that the exhumation rate increased after 4 Ma. We infer this increase to be related to the initiation of the Kung Co normal fault. A critical examination of previously published data show that most ˜ N-S Tibetan normal faults may have formed less than 5 Ma ago rather than in the Miocene as assumed by several authors. Such a young age implies that E-W extension is not related to the Neogene South Tibetan magmatism (25 to 8 Ma). Consequently, models relating E-W extension to magmatism, such as convective removal of the lower lithosphere, may be inappropriate

Recent ion cyclotron range of frequencies experiments in JT-60U

International Nuclear Information System (INIS)

Kimura, H.; Fujii, T.; Saigusa, M.; Moriyama, S.; Sato, M.; Nemoto, M.; Kondoh, T.; Hamamatsu, K.

1995-01-01

Recent results on the minority ion second harmonic heating on JT-60U are presented. Maximum coupled power reached 6.4MW. Good antenna-plasma coupling capability and a small fraction (less than 10%) of an incremental radiation loss to r.f. power are confirmed. Power absorption rate increases with increasing r.f. power and is saturated around unity at r.f. powers higher than 3MW. The sawtooth stabilization by minority ion second harmonic heating was realized over a wide parameter range, i.e. I P =0.9MA-4MA, q 95 =2.3-8.6, n e =(1.3-5)x10 19 m -3 and P IC ≥2.2MW. A figure of merit V P left angle n e right angle /P tot for efficiency of the sawtooth stabilization is about 50% higher than those in other devices where fundamental resonance minority ion heating is employed. The longest stable period reached 2.33s. Attainable sawtooth-free periods scale with the resistive diffusion time. It was found that the energy confinement is further improved by 25% during the reheating phase after the giant sawtooth crash. The electron temperature profile became more peaked at the improved confinement phase. Those phenomena were observed only in low q discharges (q 95 ≤2.9). ((orig.))

46 CFR 308.522 - Collateral deposit fund, letter of transmittal, Form MA-302.

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Collateral deposit fund, letter of transmittal, Form MA... Collateral deposit fund, letter of transmittal, Form MA-302. The standard form of letter of transmittal for use in establishing a collateral deposit fund, may be obtained from the American War Risk Agency or...

Laboratory Performance of the Single-Sided E-A-R (registered trademark) Combat Arms Hearing Protective Earplug

Science.gov (United States)

2010-01-01

Research article / Article de recherche LABORATORY PERFORMANCE OF THE SINGLE-SIDED EAR® COMBAT ARMS HEARING PROTECTIVE EARPLUG Sharon M. Abel and...external microphones for enhanced L:. -communication-? ;‘ V SOMMAIRE. Le but de cet article est de comparer 1 effet du port de bouchons conventionnels a...MA. Bekesy audiometry and loudness balance testing. In: Katz, J, editor. Handbook of clinical audiology . 3rd ed. Williams & Wilkins: Baltimore; 1985

THE DATA REDUCTION PIPELINE FOR THE SDSS-IV MaNGA IFU GALAXY SURVEY

Energy Technology Data Exchange (ETDEWEB)

Law, David R. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Cherinka, Brian [Center for Astrophysical Sciences, Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States); Yan, Renbin [Department of Physics and Astronomy, University of Kentucky, 505 Rose Street, Lexington, KY 40506-0055 (United States); Andrews, Brett H. [Department of Physics and Astronomy and PITT PACC, University of Pittsburgh, 3941 O’Hara Street, Pittsburgh, PA 15260 (United States); Bershady, Matthew A. [Department of Astronomy, University of Wisconsin-Madison, 475 N. Charter Street, Madison, WI 53706 (United States); Bizyaev, Dmitry [Apache Point Observatory, P.O. Box 59, Sunspot, NM 88349 (United States); Blanc, Guillermo A. [Departamento de Astronomía, Universidad de Chile, Camino del Observatorio 1515, Las Condes, Santiago (Chile); Blanton, Michael R. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Bolton, Adam S.; Brownstein, Joel R. [Department of Physics and Astronomy, University of Utah, 115 S 1400 E, Salt Lake City, UT 84112 (United States); Bundy, Kevin [Kavli Institute for the Physics and Mathematics of the universe, Todai Institutes for Advanced Study, the University of Tokyo, Kashiwa, 277-8583 (Kavli IPMU, WPI) (Japan); Chen, Yanmei [School of Astronomy and Space Science, Nanjing University, Nanjing 210093 (China); Drory, Niv [McDonald Observatory, Department of Astronomy, University of Texas at Austin, 1 University Station, Austin, TX 78712-0259 (United States); D’Souza, Richard; Jones, Amy; Kauffmann, Guinevere [Max Planck Institute for Astrophysics, Karl-Schwarzschild-Str. 1, D-85748 Garching (Germany); Fu, Hai, E-mail: dlaw@stsci.edu [Department of Physics and Astronomy, University of Iowa, Iowa City, IA 52242 (United States); and others

2016-10-01

Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) is an optical fiber-bundle integral-field unit (IFU) spectroscopic survey that is one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV). With a spectral coverage of 3622–10354 Å and an average footprint of ∼500 arcsec{sup 2} per IFU the scientific data products derived from MaNGA will permit exploration of the internal structure of a statistically large sample of 10,000 low-redshift galaxies in unprecedented detail. Comprising 174 individually pluggable science and calibration IFUs with a near-constant data stream, MaNGA is expected to obtain ∼100 million raw-frame spectra and ∼10 million reduced galaxy spectra over the six-year lifetime of the survey. In this contribution, we describe the MaNGA Data Reduction Pipeline algorithms and centralized metadata framework that produce sky-subtracted spectrophotometrically calibrated spectra and rectified three-dimensional data cubes that combine individual dithered observations. For the 1390 galaxy data cubes released in Summer 2016 as part of SDSS-IV Data Release 13, we demonstrate that the MaNGA data have nearly Poisson-limited sky subtraction shortward of ∼8500 Å and reach a typical 10 σ limiting continuum surface brightness μ  = 23.5 AB arcsec{sup −2} in a five-arcsecond-diameter aperture in the g -band. The wavelength calibration of the MaNGA data is accurate to 5 km s{sup −1} rms, with a median spatial resolution of 2.54 arcsec FWHM (1.8 kpc at the median redshift of 0.037) and a median spectral resolution of σ  = 72 km s{sup −1}.

Desempenho agronômico e qualidade dos frutos de bananeiras 'prata anã' e 'maçã' submetidas à adubação fosfatada

OpenAIRE

Bolfarini, Ana Carolina Batista [UNESP

2015-01-01

This study aimed to evaluate the influence of phosphorus levels on vegetative growth, the duration of the cycle, production and fruit quality of banana 'Prata Anã' and 'Maçã' at conditions of São Manuel-SP. The first agricultural cycle of the cultivars was evaluated separately. The experiment was conducted in a completely randomized design with six treatments (0, 40, 60, 80, 100 and 120 kg P2O5 ha-1) and seven repetitions. For post-harvest analysis were used five replicates per treatment. At ...

Izsoļu sistēma uz satvara “Laravel”

OpenAIRE

Kasparsons, Reinis

2015-01-01

Darbā aprakstīta informācijas sistēma, kas paredzēta uzņēmumam, kuram nepieciešama vienkārša izsoļu sistēma pakalpojumu un preču izsolei. Sistēmas klientiem tā nodrošina produkta iegādes iespēju, bet pārdevējam savu produktu un pakalpojumu vienkāršu izsoli. Sistēmas realizācija datu glabāšanai izmanto datubāzi ar SQL pieeju. Lietotāju skati tiek veidoti, izmantojot PHP, HTML5,CSS3,Bootstrap un Laravel.

Klasifikasi Kecamatan Berdasarkan Nilai Akhir SMA/MA di Kabupaten Aceh Selatan Menggunakan Analisis Diskriminan

Directory of Open Access Journals (Sweden)

Fitriana A.R.

2015-11-01

Full Text Available Analisis diskriminan merupakan bagian dari analisis peubah ganda. Analisis diskriminan digunakan untuk memodelkan variabel tak bebas yang bersifat kualitatif dengan variabel bebas yang bersifat kuantitatif. Pada penelitian ini, analisis diskriminan lebih dari dua kelompok diterapkan pada data nilai akhir SMA/MA di Kabupaten Aceh Selatan yang bertujuan untuk mendapatkan model untuk pengklasifikasian kecamatan. Pengklasifikasian ini bertujuan untuk melihat perbedaan kualitas siswa SMA/MA yang berada di masing-masing kecamatan Kabupaten Aceh Selatan berdasarkan data nilai akhir. Variabel tak bebas yang digunakan berupa klasifikasi kecamatan berdasarkan rata-rata jumlah nilai akhir SMA/MA yang berada di masing-masing kecamatan yang dibentuk dengan K-Means Cluster. Sedangkan variabel bebas yang digunakan adalah data rata-rata nilai akhir SMA/MA untuk setiap mata pelajaran yang diujiankan pada masing-masing jurusan setiap kecamatan. Model yang didapatkan adalah dua model diskriminan untuk jurusan IPA dan IPS.

Fabrication technology for ODS Alloy MA957

International Nuclear Information System (INIS)

ML Hamilton; DS Gelles; RJ Lobsinger; MM Paxton; WF Brown

2000-01-01

A successful fabrication schedule has been developed at Carpenter Technology Corporation for the production of MA957 fuel and blanket cladding. Difficulties with gun drilling, plug drawing and recrystallization were overcome to produce a pilot lot of tubing. This report documents the fabrication efforts of two qualified vendors and the support studies performed at WHC to develop the fabrication-schedule

Organisational Learning through International M&A Integration Strategies

Science.gov (United States)

Holland, Wayne; Salama, Alzira

2010-01-01

Purpose: The purpose of this research paper is to explore the learning process associated with international mergers and acquisitions (M&A) integration strategies. Design/methodology/approach: The paper employs a comparative case study methodology, utilising qualitative data through in-depth interviews with top management responsible for…

Second Generation Dutch Pulsar Machine - PuMa-II

NARCIS (Netherlands)

Karuppusamy, Ramesh; Stappers, Ben; Slump, Cornelis H.; van der Klis, Michiel

2004-01-01

The Second Generation Pulsar Machine (PuMa- II) is under development for the Westerbork Synthesis Radio Telescope. This is a summary of th e system design and architecture. We show that state of the art pulsar research is possible with commercially available hardware components. This approach

Reducción del colesterol y aumento de la capacidad antioxidante por el consumo crónico de maíz morado (Zea mays L en ratas hipercolesterolémicas

Directory of Open Access Journals (Sweden)

Jorge Arroyo

2007-04-01

Full Text Available Objetivos: Determinar la actividad hipocolesterolémica y antioxidante del consumo crónico del extracto hidroalcohólico atomizado del maíz morado (Zea mays L en ratas hipercolesterolémicas. Materiales y métodos: Se utilizaron cinco grupos de seis ratas Holtzmann cada uno, uno sin hipercolesterolemia (control negativo, y cuatro con hipercolesterolemia inducida por consumo de colesterol puro vía oral durante 60 días: control positivo y tres para las dosis de 250, 500 y 1000 mg/kg, respectivamente. En el día 60 se determinaron los niveles séricos de colesterol total, triglicéridos y colesterol HDL (mg/dL, así como de malondialdehido (mmol/L para determinar la actividad antioxidante. Se comparó la diferencias de medias con ANOVA y test de Tukey. Resultados: Se observó una disminución del colesterol total en las ratas hipercolesterolémicas que consumieron dosis de 250 y 500 mg/kg en relación con el grupo control positivo (reducción de 21,5 y 11,2% respectivamente, p<0,01. No se observaron diferencias significativas sobre los niveles de triglicéridos y colesterol HDL. A mayor dosis se maíz morado se encontró una mayor reducción de radicales libres, con la dosis de 1000 mg/kg se redujo en 56,4% los niveles de malondialdehido (p< 0,01. Conclusiones: En condiciones experimentales, el consumo crónico del extracto hidroalcohólico atomizado de maíz morado disminuye los niveles de colesterol total y aumenta la capacidad antioxidante.

Molecular mechanisms and in vitro antioxidant effects of Lactobacillus plantarum MA2.

Science.gov (United States)

Tang, Wei; Xing, Zhuqing; Li, Chao; Wang, Jinju; Wang, Yanping

2017-04-15

Lactobacillus plantarum MA2 was isolated from Chinese traditional Tibetan kefir grains. The antioxidant activities in vitro of this strain were evaluated extensively. The results showed that L. plantarum MA2 can tolerate hydrogen peroxide up to 2.0mM, and its fermentate (fermented supernatant, intact cell and cell-free extract) had strong reducing capacities, lipid peroxidation inhibition capacities, Fe 2+ -chelating abilities, as well as various free radical scavenging capacities. Additionally, both the fermented supernatant and cell homogenate exhibited glutathione peroxidase activity and superoxide dismutase activity. In order to investigate the antioxidant mechanism of L. plantarum MA2 at the molecular level, eight antioxidant-related genes were identified, and further analyzed. Three groups of genes cat, gshR and npx, were found up-regulated under H 2 O 2 challenge. Copyright © 2016 Elsevier Ltd. All rights reserved.

Flux consumption optimization and the achievement of 1 MA discharges on NSTX

International Nuclear Information System (INIS)

Menard, J.; LeBlanc, B.; Sabbagh, S.A.

2001-01-01

The spherical tokamak (ST), because of its slender central column, has very limited volt-second capability relative to a standard aspect ratio tokamak of similar plasma cross-section. Recent experiments on the National Spherical Torus Experiment (NSTX) have begun to quantify and optimize the ohmic current drive efficiency in a MA-class ST device. Sustainable ramp-rates in excess of 5MA/sec during the current rise phase have been achieved on NSTX, while faster ramps generate significant MHD activity. Discharges with I P exceeding 1MA have been achieved in NSTX with nominal parameters: aspect ratio A=1.3-1.4, elongation κ=2-2.2, triangularity δ=0.4, internal inductance l i =0.6, and Ejima coefficient C E =0.35. Flux consumption efficiency results, performance improvements associated with first boronization, and comparisons to neoclassical resistivity are described. (author)

The quality of veterinary in-clinic and reference laboratory biochemical testing.

Science.gov (United States)

Rishniw, Mark; Pion, Paul D; Maher, Tammy

2012-03-01

Although evaluation of biochemical analytes in blood is common in veterinary practice, studies assessing the global quality of veterinary in-clinic and reference laboratory testing have not been reported. The aim of this study was to assess the quality of biochemical testing in veterinary laboratories using results obtained from analyses of 3 levels of assayed quality control materials over 5 days. Quality was assessed by comparison of calculated total error with quality requirements, determination of sigma metrics, use of a quality goal index to determine factors contributing to poor performance, and agreement between in-clinic and reference laboratory mean results. The suitability of in-clinic and reference laboratory instruments for statistical quality control was determined using adaptations from the computerized program, EZRules3. Reference laboratories were able to achieve desirable quality requirements more frequently than in-clinic laboratories. Across all 3 materials, > 50% of in-clinic analyzers achieved a sigma metric ≥ 6.0 for measurement of 2 analytes, whereas > 50% of reference laboratory analyzers achieved a sigma metric ≥ 6.0 for measurement of 6 analytes. Expanded uncertainty of measurement and ± total allowable error resulted in the highest mean percentages of analytes demonstrating agreement between in-clinic and reference laboratories. Owing to marked variation in bias and coefficient of variation between analyzers of the same and different types, the percentages of analytes suitable for statistical quality control varied widely. These findings reflect the current state-of-the-art with regard to in-clinic and reference laboratory analyzer performance and provide a baseline for future evaluations of the quality of veterinary laboratory testing. © 2012 American Society for Veterinary Clinical Pathology.

TRANSFORMASI KURIKULUM PESANTREN: Telaah Pemikiran KH. MA. Sahal Mahfudh dan Nurcholish Madjid

OpenAIRE

Mukhlison Effendi; Suradi Suradi

2016-01-01

Abstract; Islamic boarding school is an indigenous Indonesia. Some contribution that given in the Islamization process, create a good community literacy and culture are very large. One reason, because there are Islamic boarding school curriculum transformation. Most influential enticement are KH. MA. Sahal Mahfudh and Nurcholish Madjid enticement. To knowing and determine the transformation both of those figures, the researcher take focus of study as: 1) the speculation of KH. MA. Sahal Mahfu...

Efecto de la adición de materia orgánica sobre la dinámica poblacional bacteriana del suelo en cultivos de papa y maíz

Directory of Open Access Journals (Sweden)

David García Ventocilla

2012-02-01

Full Text Available Se determinó el efecto de la fertilización orgánica sobre las poblaciones bacterianas del suelo en cultivos de papa y maíz durante la campaña agrícola 2008-2009 en terrenos de cuatro localidades del Valle del Mantaro: INIA Santa Ana (Huancayo, en la EEA El Mantaro (Jauja, Vista Alegre y Huayao (ambos en Chupaca. En estos lugares se instalaron parcelas experimentales de papa (Solanum tuberosum L. Var. Canchan y maíz (Zea maíz L. Var. Cusco mejorado bajo abonamiento orgánico (vacuno, ovino, cuy, fertilización química y sin fertilización alguna (testigo. Para dicho efecto se empleó las técnicas de la Electroforesis en Gel de Gradiente Desnaturalizante (DGGE con amplificación de la región 968 – 1401 del rDNA 16S. Los resultados obtenidos muestran que la variabilidad de las poblaciones bacterianas en los suelos está afectado directamente por el tipo de cultivo mas no por el tipo de fertilización ya que el efecto de este último resulta variable para cada zona experimental y cultivo encontrándose solo en la zona experimental de Chupaca - Maíz una segregación de los tratamientos con fertilización orgánica de los tratamientos químicos. También se ha encontrado que la variación de las comunidades microbianas no sufre variaciones significativas en los suelos con cultivos de maíz obteniéndose coeficientes de similaridad para todos los tratamientos por encima del 80% mientras que para los tratamientos en los cultivos de papa dicho coeficiente fue de tan solo del 60%.

Highly Stable [C60AuC60]+/- Dumbbells.

Science.gov (United States)

Goulart, Marcelo; Kuhn, Martin; Martini, Paul; Chen, Lei; Hagelberg, Frank; Kaiser, Alexander; Scheier, Paul; Ellis, Andrew M

2018-05-17

Ionic complexes between gold and C 60 have been observed for the first time. Cations and anions of the type [Au(C 60 ) 2 ] +/- are shown to have particular stability. Calculations suggest that these ions adopt a C 60 -Au-C 60 sandwich-like (dumbbell) structure, which is reminiscent of [XAuX] +/- ions previously observed for much smaller ligands. The [Au(C 60 ) 2 ] +/- ions can be regarded as Au(I) complexes, regardless of whether the net charge is positive or negative, but in both cases, the charge transfer between the Au and C 60 is incomplete, most likely because of a covalent contribution to the Au-C 60 binding. The C 60 -Au-C 60 dumbbell structure represents a new architecture in fullerene chemistry that might be replicable in synthetic nanostructures.

Laboratory Formation of Fullerenes from PAHs: Top-down Interstellar Chemistry

Science.gov (United States)

Zhen, Junfeng; Castellanos, Pablo; Paardekooper, Daniel M.; Linnartz, Harold; Tielens, Alexander G. G. M.

2014-12-01

Interstellar molecules are thought to build up in the shielded environment of molecular clouds or in the envelope of evolved stars. This follows many sequential reaction steps of atoms and simple molecules in the gas phase and/or on (icy) grain surfaces. However, these chemical routes are highly inefficient for larger species in the tenuous environment of space as many steps are involved and, indeed, models fail to explain the observed high abundances. This is definitely the case for the C60 fullerene, recently identified as one of the most complex molecules in the interstellar medium. Observations have shown that, in some photodissociation regions, its abundance increases close to strong UV-sources. In this Letter we report laboratory findings in which C60 formation can be explained by characterizing the photochemical evolution of large polycyclic aromatic hydrocarbons (PAHs). Sequential H losses lead to fully dehydrogenated PAHs and subsequent losses of C2 units convert graphene into cages. Our results present for the first time experimental evidence that PAHs in excess of 60 C-atoms efficiently photo-isomerize to buckminsterfullerene, C60. These laboratory studies also attest to the importance of top-down synthesis routes for chemical complexity in space.

LABORATORY FORMATION OF FULLERENES FROM PAHS: TOP-DOWN INTERSTELLAR CHEMISTRY

International Nuclear Information System (INIS)

Zhen, Junfeng; Castellanos, Pablo; Tielens, Alexander G. G. M.; Paardekooper, Daniel M.; Linnartz, Harold

2014-01-01

Interstellar molecules are thought to build up in the shielded environment of molecular clouds or in the envelope of evolved stars. This follows many sequential reaction steps of atoms and simple molecules in the gas phase and/or on (icy) grain surfaces. However, these chemical routes are highly inefficient for larger species in the tenuous environment of space as many steps are involved and, indeed, models fail to explain the observed high abundances. This is definitely the case for the C 60 fullerene, recently identified as one of the most complex molecules in the interstellar medium. Observations have shown that, in some photodissociation regions, its abundance increases close to strong UV-sources. In this Letter we report laboratory findings in which C 60 formation can be explained by characterizing the photochemical evolution of large polycyclic aromatic hydrocarbons (PAHs). Sequential H losses lead to fully dehydrogenated PAHs and subsequent losses of C 2 units convert graphene into cages. Our results present for the first time experimental evidence that PAHs in excess of 60 C-atoms efficiently photo-isomerize to buckminsterfullerene, C 60 . These laboratory studies also attest to the importance of top-down synthesis routes for chemical complexity in space

The New High Magnetic Field Laboratory at Dresden: a Pulsed-Field Laboratory at an IR Free-Electron-Laser

International Nuclear Information System (INIS)

Pobell, F.; Bianchi, A. D.; Herrmannsdoerfer, T.; Krug, H.; Zherlitsyn, S.; Zvyagin, S.; Wosnitza, J.

2006-01-01

We report on the construction of a new high magnetic field user laboratory which will offer pulsed-field coils in the range (60 T, 500 ms, 40 mm) to (100 T, 10 ms, 20 mm) for maximum field, pulse time, and bore diameter of the coils. These coils will be energized by a modular 50 MJ/24 kV capacitor bank. Besides many other experimental techniques, as unique possibilities NMR in pulsed fields as well as infrared spectroscopy at 5 to 150 μm will be available by connecting the pulsed field laboratory to a nearby free-electron-laser facility

Temperature Evolution of a 1 MA Triple-Nozzle Gas-Puff Z-Pinch

Science.gov (United States)

de Grouchy, Philip; Banasek, Jacob; Engelbrecht, Joey; Qi, Niansheng; Atoyan, Levon; Byvank, Tom; Cahill, Adam; Moore, Hannah; Potter, William; Ransohoff, Lauren; Hammer, David; Kusse, Bruce; Laboratory of Plasma Studies Team

2015-11-01

Mitigation of the Rayleigh-Taylor instability (RTI) plays a critical role in optimizing x-ray output at high-energy ~ 13 keV using the triple-nozzle Krypton gas-puff at Sandia National Laboratory. RTI mitigation by gas-puff density profiling using a triple-nozzle gas-puff valve has recently been recently demonstrated on the COBRA 1MA z-pinch at Cornell University. In support of this work we investigate the role of shell cooling in the growth of RTI during gas-puff implosions. Temperature measurements within the imploding plasma shell are recorded using a 527 nm, 10 GW Thomson scattering diagnostic for Neon, Argon and Krypton puffs. The mass-density profile is held constant at 22 microgram per centimeter for all three puffs and the temperature evolution of the imploding material is recorded. In the case of Argon puffs we find that the shell ion and electron effective temperatures remain in equilibrium at around 1keV for the majority of the implosion phase. In contrast scattered spectra from Krypton are dominated by of order 10 keV effective ion temperatures. Supported by the NNSA Stewardship Sciences Academic Programs.

Origin Of Black Shale (Marl) Formation Aided By Continuous Volcanism For 10Ma Including Oceanic Anoxic Event, OAE2 (93-93.5 Ma) In The Eagle Ford Formation In South Texas

Science.gov (United States)

Chakrabarty, P.; Basu, A. R.

2017-12-01

We report LA-ICPMS U-Pb ages and Hf isotopes of zircons, petrography, major and trace elements and X-ray diffraction (XRD) analyses of whole rock black shales(marls) from volcanic subsurface as well as surface exposure ash beds of the Eagle Ford and Boquillas Formations in South Texas. Zircons from the middle part of the 300ft long Eagle Ford cores yield ages of 93.2±1.66 Ma, 94.13±1.25 Ma and 93.7±1.9 Ma. These ages are consistent with the Cenomanian-Turonian (C-T) age of deposition in three contiguous cores with spatial separation of 140 miles. An approximate 10Ma duration of deposition of volcanic ash and marl, at a rate of 28ft/Ma for the Eagle Ford is suggested from the 85.76 to 95.5 Ma ages. These ages are from the Eagle Ford ash beds, below the Austin Chalk and above the Buda Limestone and cover the Oceanic Anoxic Event 2 at the C-T boundary. Zircons from 7 ash beds in the surface exposures of the Boquillas Formation near Del Rio, yield ages between 84.63 Ma - 90.91 Ma, implying younger than C-T boundary ages for these samples. The mineralogy, major and trace elements of the ash beds suggest their source from nearby arc-derived calc-alkaline volcanism. The ɛHf(T) of the analyzed ash bed zircons yield values between 0 - +8 averaging at +3.5, clearly indicating a mantle component in the host magmas of the zircons. This initial range of ɛHf(T) is similar to arc-volcanism signatures such as the Quaternary andesitic volcanism in Central Mexico. Petrographic analyses of marls away from the visible tuff layer contain phenocrysts of biotite, alkali feldspar and andesitic rock fragments. The whole rock marl with high concentration of some transition metals (V, Zn, Ni, Pb, Mo) and relatively higher MgO and TiO2 contents indicate contemporaneous arc volcanic activity at the time of marl deposition. XRD of subsurface Eagle Ford bulk marl samples from different depths in 4 cores, show volcanogenic clays, such as montmorillonite, vermiculite, dickite and halloysite

Stormwater Pollution Prevention Plan TA-60 Asphalt Batch Plant Revision 2: January 2017

Energy Technology Data Exchange (ETDEWEB)

Sandoval, Leonard Frank [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-02-01

The Stormwater Pollution Prevention Team (PPT) is applicable to operations at the Technical Area (TA)- 60 Asphalt Batch Plant (ABP) located on Eniwetok Drive/Sigma Mesa, in Los Alamos County, New Mexico at Los Alamos National Laboratory (LANL).

Çalışma Tutumu Ölçeği ve Geçerlik-Güvenirlik Analizleri

OpenAIRE

YAVUZ, Sefer

2015-01-01

Çalışma Tutumu Ölçeği ve Geçerlik-Güvenirlik Analizleri Çalışma üzerine yapılan araştırmaların çoğu çalışma ve bir başka değişken arasındaki ilişkiyi incelemeye yöneliktir. Bu araştırmada ise bireylerin/çalışanların bizzat “çalışma faaliyeti” hakkındaki tutumları ele alınmıştır. Bu amaçla Mistik Yönelimli-Teslimiyetçi Çalışma Tutumu, Kolay Kazanç Yönelimli-Hazcı Çalışma Tutumu ve İş Yönelimli-Çileci Çalışma Tutumu olmak üzere üç boyuttan oluşan bir çalışma tutumu ölçeği geliştirilmiş ve ölçeğ...

[Construction and operation status of management system of laboratories of schistosomiasis control institutions in Hubei Province].

Science.gov (United States)

Zhao-Hui, Zheng; Jun, Qin; Li, Chen; Hong, Zhu; Li, Tang; Zu-Wu, Tu; Ming-Xing, Zeng; Qian, Sun; Shun-Xiang, Cai

2016-10-09

To analyze the construction and operation status of management system of laboratories of schistosomiasis control institutions in Hubei Province, so as to provide the reference for the standardized detection and management of schistosomiasis laboratories. According to the laboratory standard of schistosomiasis at provincial, municipal and county levels, the management system construction and operation status of 60 schistosomiasis control institutions was assessed by the acceptance examination method from 2013 to 2015. The management system was already occupied over all the laboratories of schistosomiasis control institutions and was officially running. There were 588 non-conformities and the inconsistency rate was 19.60%. The non-conformity rate of the management system of laboratory quality control was 38.10% (224 cases) and the non-conformity rate of requirements of instrument and equipment was 23.81% (140 cases). The management system has played an important role in the standardized management of schistosomiasis laboratories.

Concentration of 60Co by marine organisms through sediments

International Nuclear Information System (INIS)

Nakahara, Motokazu; Koyanagi, Taku; Saiki, Masamichi

1976-01-01

Uptake of 60 Co absorbed on sea sands by benthic marine organisms was observed in laboratory experiments, since the radioactive cobalt released from nuclear power plants or other establishments into coastal seawater trends to be absorbed on sea sediments and also various kinds of marine organisms live in bottom sediments. Few kinds of flatfishes (Limanda spp.) and shrimp (Trachypenaeus curvirostris) were reared in aquariums contained seawater and sea sands which were highly contaminated with 60 Co previously, and whole body retention and distribution of radioactivity were measured on the organisms taken up from the aquariums occasionally by a scintillation counter. Uptake of 60 Co from ingested sea sands was also observed on the flatfishes administrating the contaminated sands orally. Concentration of 60 Co by the flatfishes reared in the sands was not significant while the shrimp showed high retention of the radioactivity. The food habit of shrimp which usually feeds on organic detritus with other small benthic organisms is different from that of flatfishes, one of the carnivorous, and considered to bring the difference on the pathway of radionuclides concentration. Assimilation of 60 Co via the digestive tract of flatfishes through the sands was estimated as about 10 per cent of the administrated radioactivity. (auth.)

The transcriptional regulatory network mediated by banana (Musa acuminata) dehydration-responsive element binding (MaDREB) transcription factors in fruit ripening.

Science.gov (United States)

Kuang, Jian-Fei; Chen, Jian-Ye; Liu, Xun-Cheng; Han, Yan-Chao; Xiao, Yun-Yi; Shan, Wei; Tang, Yang; Wu, Ke-Qiang; He, Jun-Xian; Lu, Wang-Jin

2017-04-01

Fruit ripening is a complex, genetically programmed process involving the action of critical transcription factors (TFs). Despite the established significance of dehydration-responsive element binding (DREB) TFs in plant abiotic stress responses, the involvement of DREBs in fruit ripening is yet to be determined. Here, we identified four genes encoding ripening-regulated DREB TFs in banana (Musa acuminata), MaDREB1, MaDREB2, MaDREB3, and MaDREB4, and demonstrated that they play regulatory roles in fruit ripening. We showed that MaDREB1-MaDREB4 are nucleus-localized, induced by ethylene and encompass transcriptional activation activities. We performed a genome-wide chromatin immunoprecipitation and high-throughput sequencing (ChIP-Seq) experiment for MaDREB2 and identified 697 genomic regions as potential targets of MaDREB2. MaDREB2 binds to hundreds of loci with diverse functions and its binding sites are distributed in the promoter regions proximal to the transcriptional start site (TSS). Most of the MaDREB2-binding targets contain the conserved (A/G)CC(G/C)AC motif and MaDREB2 appears to directly regulate the expression of a number of genes involved in fruit ripening. In combination with transcriptome profiling (RNA sequencing) data, our results indicate that MaDREB2 may serve as both transcriptional activator and repressor during banana fruit ripening. In conclusion, our study suggests a hierarchical regulatory model of fruit ripening in banana and that the MaDREB TFs may act as transcriptional regulators in the regulatory network. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

redMaPPer. I. Algorithm and SDSS DR8 catalog

Energy Technology Data Exchange (ETDEWEB)

Rykoff, E. S.; Rozo, E.; Reddick, R.; Wechsler, R. H. [SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Busha, M. T. [Institute for Theoretical Physics, University of Zürich, 8057 Zürich (Switzerland); Cunha, C. E. [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Palo Alto, CA 94305 (United States); Finoguenov, A. [Department of Physics, University of Helsinki, FI-00014 Helsinki (Finland); Evrard, A.; Koester, B. P. [Physics Department, University of Michigan, Ann Arbor, MI 48109 (United States); Hao, J.; Nord, B. [Center for Particle Astrophysics, Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Leauthaud, A. [Kavli Institute for the Physics and Mathematics of the Universe, University of Tokyo, Kashiwa 277-8583 (Japan); Pierre, M.; Sadibekova, T. [Service d' Astrophysique, CEA Saclay, F-91191 Gif sur Yvette Cedex (France); Sheldon, E. S. [Brookhaven National Laboratory, Upton, NY 11973 (United States)

2014-04-20

We describe redMaPPer, a new red sequence cluster finder specifically designed to make optimal use of ongoing and near-future large photometric surveys. The algorithm has multiple attractive features: (1) it can iteratively self-train the red sequence model based on a minimal spectroscopic training sample, an important feature for high-redshift surveys. (2) It can handle complex masks with varying depth. (3) It produces cluster-appropriate random points to enable large-scale structure studies. (4) All clusters are assigned a full redshift probability distribution P(z). (5) Similarly, clusters can have multiple candidate central galaxies, each with corresponding centering probabilities. (6) The algorithm is parallel and numerically efficient: it can run a Dark Energy Survey-like catalog in ∼500 CPU hours. (7) The algorithm exhibits excellent photometric redshift performance, the richness estimates are tightly correlated with external mass proxies, and the completeness and purity of the corresponding catalogs are superb. We apply the redMaPPer algorithm to ∼10, 000 deg{sup 2} of SDSS DR8 data and present the resulting catalog of ∼25,000 clusters over the redshift range z in [0.08, 0.55]. The redMaPPer photometric redshifts are nearly Gaussian, with a scatter σ {sub z} ≈ 0.006 at z ≈ 0.1, increasing to σ {sub z} ≈ 0.02 at z ≈ 0.5 due to increased photometric noise near the survey limit. The median value for |Δz|/(1 + z) for the full sample is 0.006. The incidence of projection effects is low (≤5%). Detailed performance comparisons of the redMaPPer DR8 cluster catalog to X-ray and Sunyaev-Zel'dovich catalogs are presented in a companion paper.

Validity of abundances derived from spaxel spectra of the MaNGA survey

Science.gov (United States)

Pilyugin, L. S.; Grebel, E. K.; Zinchenko, I. A.; Nefedyev, Y. A.; Shulga, V. M.; Wei, H.; Berczik, P. P.

2018-05-01

We measured the emission lines in the spaxel spectra of Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) galaxies in order to determine the abundance distributions therein. It has been suggested that the strength of the low-ionization lines, R2, N2, and S2, may be increased (relative to Balmer lines) in (some) spaxel spectra of the MaNGA survey due to a contribution of the radiation of the diffuse ionized gas. Consequently, the abundances derived from the spaxel spectra through strong-line methods may suffer from large errors. We examined this expectation by comparing the behaviour of the line intensities and the abundances estimated through different calibrations for slit spectra of H II regions in nearby galaxies, for fibre spectra from the Sloan Digital Sky Survey, and for spaxel spectra of the MaNGA survey. We found that the S2 strength is increased significantly in the fibre and spaxel spectra. The mean enhancement changes with metallicity and can be as large as a factor of 2. The mean distortion of R2 and N2 is less than a factor of 1.3. This suggests that Kaufmann et al.'s (2003, MNRAS, 346, 1055) demarcation line between active galactic nuclei and H II regions in the Baldwin, Phillips, & Terlevich (BPT, 1981, PASP, 93, 5) diagram is a useful criterion to reject spectra with significantly distorted strengths of the N2 and R2 lines. We find that the three-dimensional R calibration, which uses the N2 and R2 lines, produces reliable abundances in the MaNGA galaxies. The one-dimensional N2 calibration produces either reliable or wrong abundances depending on whether excitation and N/O abundance ratio in the target region (spaxel) are close to or differ from those parameters in the calibrating points located close to the calibration relation. We then determined abundance distributions within the optical radii in the discs of 47 MaNGA galaxies. The optical radii of the galaxies were estimated from the surface brightness profiles constructed based on the

Geomorphology of Ma'adim Vallis, Mars,and Associated Paleolake Basins

Science.gov (United States)

Irwin, Rossman, P., III; Howard, Alan D.; Maxwell, Ted A.

2004-01-01

Ma'adim Vallis, one of the largest valleys in the Martian highlands, appears to have originated by catastrophic overflow of a large paleola ke located south of the valley heads. Ma'adim Vallis debouched to Gus ev crater, 900 km to the north, the landing site for the Spirit Mars Exploration Rover. Support for the paleolake overflow hypothesis come s from the following characteristics: (I) With a channel width of 3 km at its head, Ma'adim Vallis originates at two (eastern and western) gaps incised into the divide of the approximately 1.1 M km(exp 2) enc losed Eridania head basin, which suggests a lake as the water source. (2) The sinuous course of Ma'adim Vallis is consistent with overland flow controlled by preexisting surface topography, and structural con trol is not evident or required to explain the valley course. (3) The nearly constant approximately 5 km width of the inner channel through crater rim breaches, the anastomosing course of the wide western tri butary, the migration of the inner channel to the outer margins of be nds in the valley's lower reach, a medial sedimentary bar approximate ly 200 m in height, and a step-pool" sequence are consistent with modeled flows of 1-5 x l0 (exp 6) m(exp 3)/s. Peak discharges were likely higher but are poorly constrained by the relict channel geometry. (4 ) Small direct tributary valleys to Ma'adim Vallis have convex-up lon gitudinal profiles, suggesting a hanging relationship to a valley that was incised quickly relative to the timescales of tributary developm ent. (5) The Eridania basin had adequate volume between the initial d ivide and the incised gap elevations to carve Ma'adim Vallis during a single flood. (6) The Eridania basin is composed of many overlapping , highly degraded and deeply buried impact craters. The floor materials of the six largest craters have an unusually high internal relief ( approximately 1 km) and slope (approximately 0.5-1.5 degrees) among d egraded Martian craters, which are usually

A novel method of sensing temperatures of magnet coils of SINP-MaPLE plasma device

International Nuclear Information System (INIS)

Pal, A M; Bhattacharya, S; Biswas, S; Basu, S; Pal, R

2014-01-01

A set of 36 magnet coils is used to produce a continuous, uniform magnetic field of about 0.35 Tesla inside the vacuum chamber of the MaPLE Device, a linear laboratory plasma device (3 m long and 0.30 m in diameter) built for studying basic magnetized plasma physics phenomena. To protect the water cooled-coils from serious damage due to overheating temperatures of all the coils are monitored electronically using low cost temperature sensor IC chips, a technique first being used in similar magnet system. Utilizing the Parallel Port of a Personal Computer a novel scheme is used to avoid deploying microprocessor that is associated with involved circuitry and low level programming to address and control the large number of sensors. The simple circuits and a program code to implement the idea are developed, tested and presently in operation. The whole arrangement comes out to be not only attractive, but also simple, economical and easy to install elsewhere

Evaluation of biodegradation of bionanocomposites of PHB/PP-g-MA/vermiculite

International Nuclear Information System (INIS)

Mesquita, P.J.P. de; Alves, T.S.; Barbosa, R.; Andrade, D. de L.A.C.S.

2014-01-01

In this work, we evaluated the process of biodegradation of PHB bionanocomposites/PP-g-MA/clay. Films were prepared with compositions of 5% PP-g-MA and 3% clay (BIO5); and 2.5% PP-g-MA and 3% clay (BIO2.5). The biodegradation test was conducted according to ASTM G 160-03 for a period of 86 days. The evaluation of biodegradation was performed by optical microscopy (MO), loss of mass, FTIR and XRD. The bionanocomposites presented change of coloration and appearance of fissures. As for loss in mass in the system presented loss of BIO2,5 22.5% and 25.9% BIO5, for 86 days of simulated soil exposure. We also observed by FTIR sharp reduction in intensity of the band corresponding to the C = O groups, indicating that the microbial attack promoted cleavage of the ester group links. By XRD, reduction in the intensity of the peaks and enlargements of the same with increasing exposure time, proving the biodegradation behavior of bionanocomposites. (author)

["StigMa" - Evaluation of a Psychological Therapy Program for Stigma-Management].

Science.gov (United States)

Schenner, Manuela; Kohlbauer, Daniela; Meise, Ullrich; Haller, Christina; Pixner-Huber, Martina; Stürz, Kristina; Günther, Verena

2018-01-01

The project "Stigma Management - StigMa" aims on the evaluation of an adaptive therapy program for patients with psychiatric illness to help them in managing internalized stigma and self-stigmatization. The patients for this pilot-study were recruited in day-hospitals of pro mente tirol . 26 patients participated in 11 group sessions, following 6 modules: "Education", "Activation of Resources", "Social Network", "Self-Esteem", "Social competence in public places" and "My personal stigma management". The control group consisted of 20 patients who did not participate in StigMa. Pre-post-evaluation was done by the Internalized Stigma of Mental Illness-Scale 1. No significant interaction effects could be observed, although in the treatment group, the burden of perceived discrimination was significantly less pronounced after training than before it. The program, however, was evaluated as being extremely positive by the participants. The program StigMa will be adapted in accordance with the suggestions of the participants and reevaluated taking into consideration methodological optimization. © Georg Thieme Verlag KG Stuttgart · New York.

Reklāma kā sociālā mārketinga elements un tās efektivitāte: CSDD sociālā TV reklāma "Orgānu donori"

OpenAIRE

Priedīte, Unda

2008-01-01

Bakalaura darba tēma ir „ Reklāma kā sociālā mārketinga elements un tās efektivitāte: CSDD sociālā TV reklāma „ Orgānu donori ””. Darbā izvirzītā hipotēze: sociālā TV reklāma „Orgānu donori” kā sociālā mārketinga elements ir bijusi efektīva un tā attaisno vizuālo un tekstuālo risinājumu izvēli, jo spēcīgas emocijas ir viens no efektīvākajiem veidiem, kā sociālo problēmu kontekstā mainīt cilvēku attieksmi un rīcību. Pēc paveiktās teorētiskās informācijas apstrādes un pētījuma rezultātu ana...

La maîtrise du temps comme enjeu de lutte

OpenAIRE

Bureau, Marie-Christine; Corsani, Antonella

2012-01-01

Le conflit social autour de la réforme du régime d'assurance chômage des intermittents du spectacle a été marqué par son intensité et par sa durée. La thèse défendue ici est que la maîtrise du temps constitue l’un des enjeux majeurs de ce conflit. L'affrontement sur le terrain économique de la régulation de l'emploi et de l'industrie culturelle s'est doublé de l'affrontement sur le temps. La question du temps ne se limite pas à la régulation du temps de travail, elle concerne la maîtrise du t...

Regulation of Banana Phytoene Synthase (MaPSY) Expression, Characterization and Their Modulation under Various Abiotic Stress Conditions

Science.gov (United States)

Kaur, Navneet; Pandey, Ashutosh; Shivani; Kumar, Prateek; Pandey, Pankaj; Kesarwani, Atul K.; Mantri, Shrikant S.; Awasthi, Praveen; Tiwari, Siddharth

2017-01-01

Phytoene synthase (PSY) is a key regulatory enzyme of carotenoid biosynthesis pathway in plants. The present study examines the role of PSY in carotenogenesis and stress management in banana. Germplasm screening of 10 Indian cultivars showed that Nendran (3011.94 μg/100 g dry weight) and Rasthali (105.35 μg/100 g dry weight) contained the highest and lowest amounts of β-carotene, respectively in ripe fruit-pulp. Nendran ripe pulp also showed significantly higher antioxidant activity as compared to Rasthali. Meta-analysis of three banana PSY genes (MaPSY1, MaPSY2, and MaPSY3) was performed to identify their structural features, subcellular, and chromosomal localization in banana genome. The distinct expression patterns of MaPSY1, MaPSY2, and MaPSY3 genes were observed in various tissues, and fruit developmental stages of these two contrasting cultivars, suggesting differential regulation of the banana PSY genes. A positive correlation was observed between the expression of MaPSY1 and β-carotene accumulation in the ripe fruit-peel and pulp of Nendran. The presence of stress responsive cis-regulatory motifs in promoter region of MaPSY genes were correlated with the expression pattern during various stress (abscisic acid, methyl jasmonate, salicylic acid and dark) treatments. The positive modulation of MaPSY1 noticed under abiotic stresses suggested its role in plant physiological functions and defense response. The amino acid sequence analysis of the PSY proteins in contrasting cultivars revealed that all PSY comprises conserved domains related to enzyme activity. Bacterial complementation assay has validated the functional activity of six PSY proteins and among them PSY1 of Nendran (Nen-PSY1) gave the highest activity. These data provide new insights into the regulation of PSY expression in banana by developmental and stress related signals that can be explored in the banana improvement programs. PMID:28421096

Obama vu de ma banlieue.

Directory of Open Access Journals (Sweden)

Olga Stanislawska

2008-12-01

Full Text Available Une petite brocante est organisée tous les jeudis sur une place proche de la Basilique de Saint-Denis. On y vend des livres, des bibelots, des bijoux fantaisies et des masques africains. L’un des vendeurs a visiblement décidé de bénéficier de l’effet Obama. J’ai pris la photo de ma fenêtre, située au dessus de ce marché. J’ai adoré ce stand, mais ce n’est qu’une fois sur l’écran de mon ordinateur que j’ai vu les petites images Banania... ! Si j’avais su, je serais ...

60 years of CERN experiments and discoveries

CERN Document Server

Di Lella, Luigi

2015-01-01

The book contains a description of the most important experimental results achieved at CERN during the past 60 years, from the mid-1950s to the latest discovery of the Higgs particle. It covers the results from early accelerators at CERN to the most recent results at the LHC and thus provides an excellent review of the achievements of this outstanding laboratory. It reflects not only the impressive scientific progress achieved during the past six decades but demonstrates also the special way of successful international collaboration developed at CERN.

Conceptual Framework: Development of Interactive Reading Malay Language Learning System (I-ReaMaLLS

Directory of Open Access Journals (Sweden)

Ismail Nurulisma

2018-01-01

Full Text Available Reading is very important to access knowledge. Reading skills starts during preschool level no matter of the types of languages. At present, there are many preschool children who are still unable to recognize letters or even words. This leads to the difficulties in reading. Therefore, there is a need of intervention in reading to overcome such problems. Thus, technologies were adapted in enhancing learning skills, especially in learning to read among the preschool children. Phonological is one of the factors to be considered to ensure a smooth of transition into reading. Phonological concept enables the first learner to easily learn reading such to learn reading Malay language. The medium of learning to read Malay language can be assisted via the supportive of multimedia technology to enhance the preschool children learning. Thus, an interactive system is proposed via a development of interactive reading Malay language learning system, which is called as I-ReaMaLLS. As a part of the development of I-ReaMaLLS, this paper focus on the development of conceptual framework in developing interactive reading Malay language learning system (I-ReaMaLLS. I-ReaMaLLS is voice based system that facilitates the preschool learner in learning reading Malay language. The conceptual framework of developing I-ReaMaLLS is conceptualized based on the initial study conducted via methods of literature review and observation with the preschool children, aged 5 – 6 years. As the result of the initial study, research objectives have been affirmed that finally contributes to the design of conceptual framework for the development of I-ReaMaLLS.

Membranas poliméricas de PE-g-MA-Al/AlPO4 impregnado com Fe, Al - utilização na recuperação de efluentes de galvanoplastia

Directory of Open Access Journals (Sweden)

Joice Andrade de Araújo

2014-01-01

Full Text Available Neste trabalho foram desenvolvidas membranas filtrantes de materiais híbridos de polietileno de alta densidade modificado com anidrido maleico e ionizado com hidróxido de alumínio (PE-g-MA-Al (matriz orgânica e fosfato de alumínio amorfo puro (AlPO4 ou impregnado com ferro e/ou alumínio (fase dispersa inorgânica. Essas membranas foram obtidas nas composições de PE-g-MA-Al (M1, PE-g-MA-Al/AlPO4 (M2, PE-g-MA-Al/AlPO4-Al (M3, PE-g-MA-Al/AlPO4-Fe (M4 e PE-g-MA-Al/AlPO4-Fe,Al (M5, na proporção de 97/3% em massa, pelo método de "casting", usando xileno à quente e sob refluxo, como solvente. As técnicas de espectroscopia na região do infravermelho (FTIR, difração de raios X (DRX, análise termogravimétrica (TGA, análise textural, tensão superficial e microscopia eletrônica de varredura (MEV serviram para comprovar a influência da natureza dos materiais e da metodologia usada na confecção das membranas na incorporação da fase inorgânica na matriz polimérica e nas propriedades dos materiais híbridos resultantes. A aplicação das membranas na recuperação de metais presentes no efluente de galvanoplastia mostrou que a presença do ferro e/ou alumínio influenciou na morfologia e nas propriedades texturais desses materiais, e consequentemente na utilização como membranas mesoporosas de ultrafiltração, com os melhores resultados apresentados por M1 e M3 na recuperação de ferro (32 e 35% e zinco (62 e 60%.

Hubungan Religiusitas dan Kebahagiaan dengan Motivasi Belajar Santri di MA Mu’allimin Yogyakarta

Directory of Open Access Journals (Sweden)

Rania Melani

2016-12-01

Full Text Available This study motivated their learning motivation often decreased due to; They have to follow different school rules, they just hang out with their male friends, they will be sanctioned if they make mistakes, lack the motivation to perform best because of the homogeneity of the students in school, the lack of time to get along with the family and you. This research aims to know relation of religiosity and happiness with learning motivation at santri in MA mu'allimin Yogyakarta, religiosity relationship with motivation to learn at santri at MA Mu'allimin Yogyakarta, happiness relationship with motivation to learn at santri at MA Mu'allimin Yogyakarta. The method used is quantitative research method. The subject of this research is santri MA Mu'allimin Yogyakarta academic year 2014-2015. Data collection techniques are with the scale of learning motivation, religiosity and happiness. The method of analysis used in this study is multiple linear regression, using the help of SPSS 19.0 for windows. The results of this study: the relationship of religiosity and happiness to the motivation of learning, a significant relationship between religiosity with learning motivation, and the relationship between happiness with learning motivation.

DVD-d. Shrek Kolmas; Ma olen legend / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2008-01-01

Lühiarvustused USA 2007.a. filmidele : animafilm "Shrek Kolmas" ("Shrek the Third", režissöörid Chris Miller, Raman Hui) ja ulmefilm "Ma olen legend" ("I Am Legend"; režissöör Francis Lawrence)

Comparative study of the wear resistance of Al₂O₃-coated MA956 superalloy

Directory of Open Access Journals (Sweden)

Canahua Loza, Hugo

2000-10-01

Full Text Available Preoxidation of the MA956 superalloy, proposed as a prosthetic biomaterial, generates a compact and inert a-alumina surface layer. The aim of this study is to assess the wear resistance provided by this alumina layer on the MA956 alloy in comparison with the same coated alloy and versus high density polyethylene. Comparative wear tests were carried out in both dry and wet conditions using the couples MA956/MA956, MA956/UHMWPE (ultra high molecular weight polyethylene and 316LVM/UHMWPE. The results corresponding to the couples MA956/MA956, with and without alumina layer, show that the load has more significant effect than the rotation speed on the weight loss and on the roughness. On the other hand the alumina surface layer provides a clear wear protection. The weight losses of the MA956 specimen in this couple are ten times lower when testing under wet conditions than under dry conditions. The MA956/UHMWPE couple behaves much better than the 316LVM/UHMWPE, as it presents the lowest values of friction coefíicient and weight losses of the MA956 specimen. These are only detectable after 70,000 cycles under a 70 MPa contact pressure. This couple offers the best guarantee of a prolonged service life for articulated parts in a prosthesis.

La superaleación MA956, que se ha propuesto como biomaterial para prótesis osteoarticulares genera, mediante un adecuado tratamiento de preoxidación, una capa superficial, compacta e inerte, de alúmina alfa. El objetivo del presente trabajo es el estudio de la resistencia al desgaste de esta capa de alúmina, cuando se encuentra en contacto con la propia aleación recubierta y con polietileno de alta densidad. Se realizaron ensayos comparativos de desgaste, tanto en seco como en húmedo, con los pares MA956/MA956, MA956/UHMWPE (polietileno de muy elevado peso molecular y 316LVM/UHMWPE. Los resultados obtenidos con el par MA956/MA956, con y sin capa de alúmina, indican que la carga es el factor de mayor

Oxygen induced reactions at 200 and 60 GeV/nucleon

International Nuclear Information System (INIS)

Schmidt, H.R.; Albrecht, R.; Claesson, G.; Bock, R.; Gutbrod, H.H.; Kolb, B.W.; Lund, I.; Siemiarczuk, T.; Awes, T.C.; Baktash, C.; Ferguson, R.L.; Johnson, J.W.; Lee, I.Y.; Obenshain, F.E.; Plasil, F.; Sorensen, S.P.; Young, G.R.; Beckmann, P.; Berger, F.; Dragon, L.; Glasow, R.; Kampert, K.H.; Loehner, H.; Peitzmann, T.; Purschke, M.; Santo, R.; Franz, A.; Kristiansson, P.; Poskanzer, A.M.; Ritter, H.G.; Garpman, S.; Gustafsson, H.A.; Oskarsson, A.; Otterlund, I.; Persson, S.; Stenlund, E.

1987-10-01

In November 1987, 16 O beams of 200 and 60 GeV/nucleon, were delivered to five major experiments at the CERN SPS simultaneously. This opened for the first time the possibility to study ultra-relativistic heavy-ion collisions and to investigate the possible existence of a transition to the quark-gluon plasma under controlled conditions in the laboratory. (orig./HSI)

Study of MA Effect on Yield Strength and Ductility of X80 Linepipe Steels Weld

Science.gov (United States)

Huda, Nazmul; Lazor, Robert; Gerlich, Adrian P.

2017-09-01

Multipass GMAW (Gas Metal Arc Welding) welding was used to join X80 linepipe materials using two weld metals of slightly different compositions. Welding wires with diameters of 0.984 and 0.909 mm were used while applying the same heat input in each pass. The slight difference in the wire diameters resulted in different HAZ microstructures. The microstructures in the doubly reheated HAZ of both welds were found to contain bainite-ferrite. However, etching also revealed a difference in martensite-austenite (MA) fraction in these reheated zones. The MA exhibited twice the hardness of ferrite when measured by nanoindentation. Tensile testing from the reheated zone of both welds revealed a difference in yield strength, tensile strength and elongation of the transverse weld specimens. In the reheated zone of weld A, (produced with a 0.984 mm wire) a higher fraction of MA was observed, which resulted in higher strength but lower elongation compared to weld B. The ductility of weld A was found severely impaired (to nearly half of weld B) due to formation of closely spaced voids around the MA, along with debonding of MA from the matrix, which occurs just above the yield stress.

Maíz: Alimento fundamental en las tradiciones y costumbres mexicanas

OpenAIRE

José de Jesús Cuevas Mejía

2014-01-01

El siguiente trabajo busca recalcar la importancia del maíz para el pueblo mexicano, que con el paso de los años ha logrado mantener su identidad no en vano por la fuerza y majestuosidad de sus tradiciones y costumbres. Es cierto que hoy en día es la base de la alimentación de muchas familias a lo largo del territorio de México, en cada hogar a la hora del almuerzo, la comida e incluso la merienda, el maíz está presente en una gran variedad de formas, texturas y colores. Esto nos hace pensar ...

Cobalt-60 production in CANDU power reactors

International Nuclear Information System (INIS)

Malkoske, G.R.; Norton, J.L.; Slack, J.

2002-01-01

MDS Nordion has been supplying cobalt-60 sources to industry for industrial and medical purposes since 1946. These cobalt-60 sources are used in many market and product segments, but are primarily used to sterilize single-use medical products including; surgical kits, gloves, gowns, drapes, and cotton swabs. Other applications include sanitization of cosmetics, microbial reduction of pharmaceutical raw materials, and food irradiation. The technology for producing the cobalt-60 isotope was developed by MDS Nordion and Atomic Energy of Canada Limited (AECL) almost 55 years ago using research reactors at the AECL Chalk River Laboratories in Ontario, Canada. The first cobalt-60 source produced for medical applications was manufactured by MDS Nordion and used in cancer therapy. The benefits of cobalt-60 as applied to medical product manufacturing, were quickly realized and the demand for this radioisotope quickly grew. The same technology for producing cobalt-60 in research reactors was then designed and packaged such that it could be conveniently transferred to a utility/power reactor. In the early 1970's, in co-operation with Ontario Power Generation (formerly Ontario Hydro), bulk cobalt-60 production for industrial irradiation applications was initiated in the four Pickering A CANDU reactors. As the demand and acceptance of sterilization of medical products grew, MDS Nordion expanded its bulk supply by installing the proprietary Canadian technology for producing cobalt-60 in additional CANDU reactors. CANDU is unique among the power reactors of the world, being heavy water moderated and fuelled with natural uranium. They are also designed and supplied with stainless steel adjusters, the primary function of which is to shape the neutron flux to optimize reactor power and fuel bum-up, and to provide excess reactivity needed to overcome xenon-135 poisoning following a reduction of power. The reactor is designed to develop full power output with all of the adjuster

The Launch of the MA-6, Friendship 7

Science.gov (United States)

1962-01-01

The launch of the MA-6, Friendship 7, on February 20, 1962. Boosted by the Mercury-Atlas vehicle, a modified Atlas Intercontinental Ballistic Missile (ICBM), Friendship 7 was the first U.S. marned orbital flight and carried Astronaut John H. Glenn into orbit. Astronaut Glenn became the first American to orbit the Earth.

Analysis of MaACS2, a stress-inducible ACC Synthase Gene in Musa acuminata AAA Group Cultivar Pisang Ambon

Directory of Open Access Journals (Sweden)

Resnanti Utami Handayani

2014-07-01

Full Text Available Ethylene has an important function in plant growth and development. Ethylene production generally increases in response to pathogen attacks and other environmental stress conditions. The synthesis of this phytohormone is regulated by two enzymes, ACC synthase (ACS and ACC oxidase (ACO. ACC synthase is encoded by a multigene that regulates the production of ACC, after which this precursor is converted into ethylene by ACO. Pisang Ambon (Musa sp. AAA group, a banana cultivar originating from Indonesia, has nine ACS genes (MaACS 1-9 and one ACO gene (MaACO. One of the banana ACS genes, MaACS2, is stress-inducible. In this research, we have investigated the expression profile of MaACS2 in the roots and leaf tissues of infected tissue culture plants. Quantification of gene expression was analyzed using Real-Time PCR (qPCR using Ma18srRNA and MaGAPDH as reference genes. The results showed nine-to ten fold higher MaACS2 expression levels in the infected roots tissues compared to the uninfected roots tissues. However, MaACS2 expression in the leaves was only detected in infected tissue.

Design of Plasma Facing Components for Superconducting Modification of JT-60

International Nuclear Information System (INIS)

Shinji Sakurai; Kei Masaki; Yusuke-Kudo Shibama; Hiroshi Tamai; Makoto Matsukawa; Cordier, J.J.

2006-01-01

JT-60 is planning to modify the machine as a fully superconducting coil tokamak (JT-60 Super Advanced, the former JT-60SC and NCT) to establish scientific and technological bases for an economically and environmentally attractive DEMO reactor. It will be also a satellite tokamak in a part of broader approach for ITER. It is designed for high beta (betaN = 3.5-5.5) and steady-state research in a break-even class DD plasma for 100 s or longer. Nominal plasma parameters are I p =5.5 MA, B t =2.7 T, R=3.01 m, a=1.14 m with double-null configuration. An ITER-like single-null configuration with I p =3.5 MA, B t =2.6 T can be also operated. In order to study the ITER-relevant high confinement plasma with high density, designed plasma heating power was enhanced from 25 MW to 41 MW for 100 s through the design review with EU and Japan. The heat flux onto outer divertor target exceeds 10 MW/m 2 with moderate radiative fraction of 50-60% in single-null configuration. Therefore, the ITER-like mono-block CFC target will be adopted to aim at power handling of 15 MW/m 2 . A cooling water system should be reinforced 3 times from original design for double null divertor with high coolant flow velocity of ∼10 m/s. The peak heat flux onto the neutral beam armor for perpendicular injected positive NB is evaluated to be 2 MW/m 2 , which needs to be actively water-cooled. A bolt-fixed CFC tile was tested at the heat flux of 1-3 MW/m 2 and will be applied to the NB armor. In order to improve plasma beta value by enhancing wall stabilization effect, passive-stabilizing plates, which are electrically and mechanically connected in poloidal and toroidal direction, will be installed near the plasma surface (r wall /a=1.1-1.3) at the outboard side. Stabilizing plate has double-wall ribbed structure and can be operated at 573 K with heating nitrogen gas instead of cooling water between double walls. It has crank-type support legs to allow thermal expansion at high temperature operation. The

Alternativas para favorecer la polinización y producción de semilla del híbrido h-311 de maíz

Directory of Open Access Journals (Sweden)

Alejandro Espinosa

2001-01-01

Full Text Available Alternativas para favorecer la polinización y producción de semilla del híbrido H-311 de maíz. En la producción de semilla de híbridos de maíz es fundamental la coincidencia en floración de los progenitores y la disposición de los estigmas con respecto a las panojas que emiten polen. El híbrido de maíz H-311, se recomienda en México para siembras de riego, en alturas de 1200 a 1800 msnm. El orden de cruza inicial fue: (B16XB17 X (B32XB33; sin embargo, se cambio al orden inverso, es decir, (B32XB33 X (B16XB17, debido a mayor productividad y semilla de buena calidad física. La cruza simple (B16XB17 es enana (braquítico, al no haber suficiente viento en la época de polinización, se dificulta el cruzamiento y se requiere levantar el polen con mochilas de motor, la cruza simple B16XB17, rinde de 4,5 a 5,5 t/ha de semilla contra 6,0 a 7,5 t/ha de la cruza simple B32XB33; La cruza simple B16XB17, responde con alargamiento del porte por la influencia del tratamientos, con ácido giberélico (Activol, 20, 40 y 60 ppm, dos dosis de Cloruro de Mepiquat (PIX, 1 y 2 lt/ha, así como tres niveles de fertilización (400-70-30, 150-70-30 y 150- 300-30. En rendimiento hubo un efecto positivo por el manejo de ambos progenitores con diferentes fertilizaciones así como aplicación de fitohormonas, al aplicar ácido giberélico (20 ppm, el rendimiento se incrementó en 250,3% y 211,8% para las cruzas simples B32XB33 y B16XB17 respectivamente. La altura de planta de B16XB17 fue ligeramente afectada (106,0% con ácido giberélico, 40 ppm

MA-23-6000: underwater bilateral servo master slave manipulator

International Nuclear Information System (INIS)

Vertut, Jean

The different types of manipulators, recent data on their dexterity and the underwater work possible with servo master slave manipulators are reviewed. The general specifications of the manipulator MA 23-6000 designed for the machine ERIC II are given [fr

A Multi-Approach Evaluation System (MA-ES) of Organic Rankine Cycles (ORC) used in waste heat utilization

International Nuclear Information System (INIS)

Shu, Gequn; Yu, Guopeng; Tian, Hua; Wei, Haiqiao; Liang, Xingyu

2014-01-01

Highlights: • The MA-ES provides comprehensive valuations on ORC used for waste heat utilization. • The MA-ES covers energetic, exergetic and economic evaluations of typical ORCs. • The MA-ES is a general assessing method without restriction to specific ORC condition. • Two ORC cases of ICE waste-heat-recovery are exemplified applying the MA-ES. - Abstract: A Multi-Approach Evaluation System (MA-ES) is established in this paper providing comprehensive evaluations on Organic Rankine Cycles (ORC) used for waste heat utilization. The MA-ES covers three main aspects of typical ORC performance: basic evaluations of energy distribution and system efficiency based on the 1st law of thermodynamics; evaluations of exergy distribution and exergy efficiency based on the 2nd law of thermodynamics; economic evaluations based on calculations of equipment capacity, investment and cost recovery. The MA-ES is reasonably organized aiming at providing a general method of ORC performance assessment, without restrictions to system configurations, operation modes, applications, working fluid types, equipment conditions, process parameters and so on. Two ORC cases of internal combustion engines’ (ICEs) waste-heat-recovery are exemplified to illustrate the applications of the evaluation system. The results clearly revealed the performance comparisons among ORC configurations and working fluids referred. The comparisons will provide credible guidance for ORC design, equipment selection and system construction

Fieldbus: technology application in a 60Co sterilization plant

International Nuclear Information System (INIS)

Karam, D.; Sampa, M.H.O.; Rela, P.R.

2000-01-01

Process instrumentation was made by pressure signals in the 1940s. In the 1960s, 4-20 mA analogue signals were introduced. The development of digital processors in the 1970s sparked the use of computers to monitor and control instruments from a central point. In the 1980s smart sensors were developed and implemented in digital control, microprocessor environments. Fieldbus is a generic-term that describes a new digital communications network. The network is a digital, bi-directional, multidrop, serial-bus, and communications network used to link isolated field devices, such as controllers, transducers, actuators and sensors. Fieldbus technology may improve quality, reduce costs and increase efficiency because information is transmitted digitally without analog to digital or digital to analog converters, which also minimizes hardware errors. Fieldbus communication is based on two-wire communication, interconnecting all the components in the system. This paper introduces Fieldbus technology in a 60 Co sterilization plant

NEW IRRADIATION RESEARCH FACILITIES AT THE ARMY NATICK LABORATORIES

Energy Technology Data Exchange (ETDEWEB)

Cooper, R. D.; Brynjolfsson, A.

1963-03-15

New facilities built by the U. S. Army for research on the preservation of food by ionizing radiation consist of a food processing and packaging facility and a radiation sources laboratory with two powerful low-energy radiation sources. One is a 1.3 million-curie Co/sup 60/ source consisting of 98 tubes each containing four doubly encapsulated Co/sup 60/ slugs. The second source is an electron linear accelerator with energy variable between 2 and 32 Mev. Research with the Co/sup 60/ source is concentrated on investigation of macroscopic and microscopic dose distribution in different materials irradiated with Co/sup 60/ gamma rays. Research with the linear accelerator is concentrated on dosimetry and photonuclear reactions. (A.G.W.)

Measurements of 60Co in spoons activated by neutrons during the JCO criticality accident at Tokai-mura in 1999

International Nuclear Information System (INIS)

Gasparro, J.; Hult, M.; Komura, K.; Arnold, D.; Holmes, L.; Johnston, P.N.; Laubenstein, M.; Neumaier, S.; Reyss, J.-L.; Schillebeeckx, P.; Tagziria, H.; Van Britsom, G.; Vasselli, R.

2004-01-01

Neutron activated items from the vicinity of the place where the JCO criticality accident occurred have been used to determine the fluence of neutrons around the facility and in nearby residential areas. By using underground laboratories for measuring the activation products, it is possible to extend the study to also cover radionuclides with very low activities from long-lived radionuclides. The present study describes γ-ray spectrometry measurements undertaken in a range of underground laboratories for the purpose of measuring 60 Co more than 2 years after the criticality event. The measurements show that neutron fluence determined from 60 Co activity is in agreement with previous measurements using the short-lived radionuclides 51 Cr and 59 Fe. Limits on contamination of the samples with 60 Co are evaluated and shown to not greatly affect the utility of neutron fluence determinations using 60 Co activation

Measurements of 60Co in spoons activated by neutrons during the JCO criticality accident at Tokai-mura in 1999.

Science.gov (United States)

Gasparro, J; Hult, M; Komura, K; Arnold, D; Holmes, L; Johnston, P N; Laubenstein, M; Neumaier, S; Reyss, J-L; Schillebeeckx, P; Tagziria, H; Van Britsom, G; Vasselli, R

2004-01-01

Neutron activated items from the vicinity of the place where the JCO criticality accident occurred have been used to determine the fluence of neutrons around the facility and in nearby residential areas. By using underground laboratories for measuring the activation products, it is possible to extend the study to also cover radionuclides with very low activities from long-lived radionuclides. The present study describes gamma-ray spectrometry measurements undertaken in a range of underground laboratories for the purpose of measuring (60)Co more than 2 years after the criticality event. The measurements show that neutron fluence determined from (60)Co activity is in agreement with previous measurements using the short-lived radionuclides (51)Cr and (59)Fe. Limits on contamination of the samples with (60)Co are evaluated and shown to not greatly affect the utility of neutron fluence determinations using (60)Co activation.

46 CFR 308.524 - Application for cancellation of Open Cargo Policy, Form MA-304.

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Application for cancellation of Open Cargo Policy, Form... § 308.524 Application for cancellation of Open Cargo Policy, Form MA-304. The standard form of application for cancellation of an Open Cargo Policy Form MA-304 may be obtained from the American War Risk...

MaROS Strategic Relay Planning and Coordination Interfaces

Science.gov (United States)

Allard, Daniel A.

2010-01-01

The Mars Relay Operations Service (MaROS) is designed to provide planning and analysis tools in support of ongoing Mars Network relay operations. Strategic relay planning requires coordination between lander and orbiter mission ground data system (GDS) teams to schedule and execute relay communications passes. MaROS centralizes this process, correlating all data relevant to relay coordination to provide a cohesive picture of the relay state. Service users interact with the system through thin-layer command line and web user interface client applications. Users provide and utilize data such as lander view periods of orbiters, Deep Space Network (DSN) antenna tracks, and reports of relay pass performance. Users upload and download relevant relay data via formally defined and documented file structures including some described in Extensible Markup Language (XML). Clients interface with the system via an http-based Representational State Transfer (ReST) pattern using Javascript Object Notation (JSON) formats. This paper will provide a general overview of the service architecture and detail the software interfaces and considerations for interface design.

A "embolada" em Macunaíma

Directory of Open Access Journals (Sweden)

Raimunda B. Batista

2004-12-01

Full Text Available Os intelectuais do modernismo brasileiro tiveram como preocupação a redefinição da cultura brasileira tomando como ponto de partida a cultura popular e o folclore brasileiros. Em Macunaíma, Mário de Andrade aproveita os mais variados elementos da cultura popular, dando-lhes uma configuração erudita. Entre esses elementos destacamos o aproveitamento da embolada que, enquanto modo de cantar, possui uma forte estrutura poética, podendo ser aproveitada na prosa de ficção, conservando o seu ritmo e forma.

Effect of Fast Neutron to MA/PU Burning/Transmutation Characteristic Using a Fast Reactor

International Nuclear Information System (INIS)

Marsodi; Lasman, As Natio; Kimamoto, A.; Marsongkohadi; Zaki, S.

2003-01-01

MA/Pu burning/transmutation has been studied and evaluated using fast neutrons. Generally, neutron density at this fast burner reactor and transmutation has spectrum energy level around 0.2 MeV with wide enough variation, i.e. from low neutron spectrum to its peak is 0.2 MeV. This neutron spectrum energy level depends on the kind of cooler material or fuel used. Neutron spectrum higher than fast power reactor neutron spectrum is found by means of changing oxide fuel by metallic fuel and changing natrium cooler material by metallic or gas cooler material. This evaluation is conducted by various variations in accordance with the kind of fuel or cooler, MA/Pu fractions and fuel comparison fraction with respect to its cooler in order to get better neutron usage and MA/Pu burning speed. Reactor calculation evaluation in this paper was conducted with 26-group nuclear data cross section energy spectrum. The main purpose of the discussion is to know the effect of fast neutrons to burning/transmutation MA/Pu using fast neutrons

First results from quality assurance testing of MaPMTs for the LHCb RICH upgrade

Science.gov (United States)

Gambetta, S.; LHCb RICH Collaboration

2017-12-01

In 2019 the LHCb RICH detector will be upgraded to increase the read out rate from 1 MHz to 40 MHz. As a consequence, the current Hybrid Photon Detectors will have to be replaced. Multi-anode Photomultiplier Tubes (MaPMTs) from Hamamatsu with 64-channels will be used: the 1-in. R13742 and the 2-in. R13743 MaPMTs (custom modifications of the MaPMTs R11625 and R12699). Quality assurance testing of these MaPMTs using custom-developed readout electronics has started. We present the design and realisation of the test facilities to ensure consistency in testing and validation. A total of 3100 units of the R13742 and 450 units of the R13743 will be tested requiring high efficiency and reliability from the test stations. We report on the test programme and protocols, characterising the units and assuring compliance with specifications. First results of testing and detector characterisation will be presented, based on the pre-series production, comprising 54 units of R13742 and 20 units of R13743.

Radiation hardening and irradiation testing of in-cell electronics for MA23/APM

International Nuclear Information System (INIS)

Friant, A.

1988-09-01

We relate briefly the radiation hardening method used to guarantee a gamma resistance of 10 Mrad for the whole electronic equipment associated with the slave arm of MA23 M servomanipulator which will be set up in cell 404 in Marcoule (APM). We describe the radiation testing of electronic devices and of the various subsystems designed by the D. LETI groups involved in the MA23/APM project

Advanced Query and Data Mining Capabilities for MaROS

Science.gov (United States)

Wang, Paul; Wallick, Michael N.; Allard, Daniel A.; Gladden, Roy E.; Hy, Franklin H.

2013-01-01

The Mars Relay Operational Service (MaROS) comprises a number of tools to coordinate, plan, and visualize various aspects of the Mars Relay network. These levels include a Web-based user interface, a back-end "ReSTlet" built in Java, and databases that store the data as it is received from the network. As part of MaROS, the innovators have developed and implemented a feature set that operates on several levels of the software architecture. This new feature is an advanced querying capability through either the Web-based user interface, or through a back-end REST interface to access all of the data gathered from the network. This software is not meant to replace the REST interface, but to augment and expand the range of available data. The current REST interface provides specific data that is used by the MaROS Web application to display and visualize the information; however, the returned information from the REST interface has typically been pre-processed to return only a subset of the entire information within the repository, particularly only the information that is of interest to the GUI (graphical user interface). The new, advanced query and data mining capabilities allow users to retrieve the raw data and/or to perform their own data processing. The query language used to access the repository is a restricted subset of the structured query language (SQL) that can be built safely from the Web user interface, or entered as freeform SQL by a user. The results are returned in a CSV (Comma Separated Values) format for easy exporting to third party tools and applications that can be used for data mining or user-defined visualization and interpretation. This is the first time that a service is capable of providing access to all cross-project relay data from a single Web resource. Because MaROS contains the data for a variety of missions from the Mars network, which span both NASA and ESA, the software also establishes an access control list (ACL) on each data record

M&A flows and the foreign exchange markets:practical experiences

Directory of Open Access Journals (Sweden)

Martijn A. Schrijvers

2002-03-01

Full Text Available The large cross-border Merger and Acquisition flows of the last three years were seen by financial markets as one of the factors behind movements in exchange rates. However, the extent to which an M&A-transaction actually leads to a foreignexchange transaction is dependent on the financing and transaction techniques used and is difficult to measure. In this article, we analyse which considerations underlie the decisions of corporate Treasurers regarding the financing of take-overs and the techniques to be used by forex transactions. We investigate the effect Treasurers believe M&A transactions have on exchange rates and examine whether different techniques make for different effects. The information was obtained through interviews with Treasurers of multinationals conducting large-scale M&A activities.

C{sub 60} AS A PROBE FOR ASTROPHYSICAL ENVIRONMENTS

Energy Technology Data Exchange (ETDEWEB)

Brieva, A. C.; Jäger, C.; Huisken, F. [Laboratory Astrophysics Group of the Max Planck Institute for Astronomy at the Friedrich Schiller University Jena, Institute of Solid State Physics, Helmholtzweg 3, D-07743 Jena (Germany); Gredel, R.; Henning, T., E-mail: aab01@alumni.aber.ac.uk [Max Planck Institute for Astronomy (MPIA), Königstuhl 17, D-69117 Heidelberg (Germany)

2016-08-01

The C{sub 60} molecule has been recently detected in a wide range of astrophysical environments through its four active intramolecular vibrational modes ( T {sub 1u}) near 18.9, 17.4, 8.5, and 7.0 μ m. The strengths of the mid-infrared emission bands have been used to infer astrophysical conditions in the fullerene-rich regions. Widely varying values of the relative intrinsic strengths (RIS) of these four bands are reported in laboratory and theoretical papers, which impedes the derivation of the excitation mechanism of C{sub 60} in the astrophysical sources. The spectroscopic analysis of the C{sub 60} samples produced with our method delivers highly reproducible RIS values of 100, 25 ± 1, 26 ± 1 and 40 ± 4. A comparison of the inferred C{sub 60} emission band strengths with the astrophysical data shows that the observed strengths cannot be explained in terms of fluorescent or thermal emission alone. The large range in the observed 17.4 μ m/18.9 μ m emission ratios indicates that either the emission bands contain significant contributions from emitters other than C{sub 60}, or that the population distribution among the C{sub 60} vibrational modes is affected by physical processes other than thermal or UV excitation, such as chemo-luminescence from nascent C{sub 60} or possibly Poincaré fluorescence resulting from an inverse internal energy conversion. We have carefully analyzed the effect of the weakly active fundamental modes and second order modes in the mid-infrared spectrum of C{sub 60}, and propose that neutral C{sub 60} is the carrier of the unidentified emission band at 6.49 μ m which has been observed in fullerene-rich environments.

C60+ - looking for the bucky-ball in interstellar space

Science.gov (United States)

Galazutdinov, G. A.; Shimansky, V. V.; Bondar, A.; Valyavin, G.; Krełowski, J.

2017-03-01

The laboratory gas-phase spectrum recently published by Campbell et al. has reinvigorated attempts to confirm the presence of the C_{60}^+ cation in the interstellar medium, through an analysis of the spectra of hot, reddened stars. This search is hindered by at least two issues that need to be addressed: (I) the wavelength range of interest is severely polluted by strong water-vapour lines coming from the Earth's atmosphere; (II) one of the major bands attributed to C_{60}^+, at 9633 Å, is blended with the stellar Mg II line, which is susceptible to non-local thermodynamic equilibrium effects in hot stellar atmospheres. Both these issues are carefully considered here for the first time, based on high-resolution and high signal-to-noise ratio echellé spectra for 19 lines of sight. The result is that the presence of C_{60}^+ in interstellar clouds is brought into question.

Radioactive waste management in sealed sources laboratory production

International Nuclear Information System (INIS)

Carvalho, Gilberto

2001-01-01

The laboratory of sealed sources production, of Instituto de Pesquisas Energeticas e Nucleares, was created in 1983 and since then, has produced radioactive sources for industry and engineering in general, having specialization in assembly of radiation sources for non destructive testings, by gammagraphy, with Iridium-192, that represents 98% of the production of laboratory and 2% with the Cobalt-60, used in nuclear gages. The aim of this work, is to quantify and qualify the radioactive wastes generated annually, taking into account, the average of radioactive sources produced, that are approximately 220 sources per year

42 CFR 422.74 - Disenrollment by the MA organization.

Science.gov (United States)

2010-10-01

... providing reasonable accommodations, as determined by CMS, for individuals with mental or cognitive conditions, including mental illness and developmental disabilities. In addition, the MA organization must... timeframes specified in § 422.506(a)(2). (e) Consequences of disenrollment—(1) Disenrollment for non-payment...

Ma ma (2015: un reflejo de la mujer española con cáncer de mama

Directory of Open Access Journals (Sweden)

Clara Peralta?Nueno et al.

2017-03-01

Full Text Available Ma ma (2015 es una película de drama española dirigida por Julio Medem y producida por Morena Films. Esta película narra la historia de la vida de Magda cuyo personaje es interpretado por Penélope Cruz. Tras serle diagnosticado un cáncer de mama, Magda, una maestra en paro, no sabrá cómo actuar ni de qué manera cambiará esta enfermedad su vida, pero poco a poco sacará a la superficie toda su energía vital. El cáncer de mama representa el tipo de cáncer más frecuente en la mujer. Aunque la mayoría de los factores de riesgo identificados pueden ser modificables, los sistemas de salud se concentran en actividades que permiten fortalecer la prevención primaria y actividades de prevención secundaria y terciaria. La detección temprana y el tratamiento adecuado son indispensables para luchar contra esta enfermedad. El proceso emocional generado por la presencia de cáncer, conlleva un mecanismo de reconstitución psíquico que permite a la paciente conformar una respuesta a los desafíos orgánicos, cognitivos, sociales y emocionales a los cuales se ve enfrentada. Dicho proceso es favorecido entre otros factores por contar con una red de apoyo socio?familiar sólida.

46 CFR 308.523 - Application for revision of Open Cargo Policy, Form MA-303.

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Application for revision of Open Cargo Policy, Form MA... Application for revision of Open Cargo Policy, Form MA-303. An application for the revision of an Open Cargo Policy shall be filed in duplicate with the Underwriting Agent on a form which may be obtained from the...

The International Diversification of Banks and the Value of their Cross-Border M&A Advice

NARCIS (Netherlands)

de Jong, A.; Ongena, S.; van der Poel, M.

2010-01-01

This paper investigates the effects of international diversification of banks on the value of their M&A advice. We study bidder returns to 1,253 cross-border M&A announcements. We find that acquirers engaging a more internationally diversified financial advisor generate lower excess returns.

M&A New Rules May Trigger Merger Wave

Institute of Scientific and Technical Information of China (English)

HUBERT TSE

2006-01-01

@@ The Chinese government issued a series of new M&A and takeover rules in July and August 2006 to further regulate and facilitate foreign investors' acquisition activities in China.The new rules are aimed at offering more flexibility, reducing costs and increasing takeover efficiencies for foreign-funded M&As in the world's fastest-growing major economy.

Low-dose respiratory-gated PET/CT: based on 30 mA tube current

International Nuclear Information System (INIS)

Wu Ping; Li Sijin; Zhang Yanlan; Hao Xinzhong; Qin Zhixing; Yan Min; Cheng Pengliang; Wu Zhifang

2013-01-01

Objective: To establish a low-dose but image-comparable respiratory-gated PET/CT (RG PET/CT) protocol based on 30 mA tube current plus other improved scanning parameters, such as the tube current, the number of respiratory phase and length of breathing cycle. Methods: Twenty-six patients with 18 F-FDG-intaking lung nodules underwent one-bed standard-dose PET/CT (120 mA, 2 min/bed) and low dose RG PET/CT (30 mA, 6 respiratory phases, 1 min/phase). The radiation dose and image quality were analyzed subsequently with signal to noise ratio (SNR) for PET and the homogeneity, noise level for CT in the water phantom respectively. Otherwise the CT images were both visual evaluated by two experienced doctors. In addition, different respiratory cycle was simulated to observe its relation with radiation dose. Results: The effective dose of low-dose RG PET/CT was 4.88∼7.69 mSv [mean (5.68±0.83) mSv]. The PET SNR showed no significance between groups. The homogeneity of 30 mA is good (< 5 HU), although noise level was high, the visual character like lobulation, speculation of lung nodule was superior in some respiratory phases. The radiation dose was positively correlated with respiratory cycle. Conclusions: The performance of low-dose RG PET/CT was comparable to those of standard-dose PET/CT based on a protocol with 30 mA tube current, 6 respiratory phases and breathing state of eupnoea. It produced a much lower radiation exposure and the image quality was enough for clinical use such as delineation of tumor active target, characterization and staging of lung nodules, etc. (authors)

Estrategias de reproducción social de los productores de maíz de Tlaxcala

Directory of Open Access Journals (Sweden)

Miguel Ángel Damián Huato

2009-01-01

Full Text Available Se analizan las múltiples estrategias de reproducción social de los productores de maíz del estado de Tlaxcala y el efecto que ha tenido la pluriactividad en el manejo del maíz y de otros recursos, así como en el desarrollo sustentable y humano. Con este fin se recurrió a información acopiada por una encuesta aplicada en el año de 2002 a una muestra de 1,884 maiceros. Los resultados indican que, aparte de producir maíz, 74% vende su fuerza de trabajo para sobrevivir, realizando distintas actividades; una sexta parte de productores o de sus familiares tienen que emigrar para contribuir al sustento familiar; las actividades pri- marias (siembra de maíz, ganadería y recolección de bienes, aunque aportan menor cantidad de recursos económicos, son estrategias de gran importancia por garantizar la reproducción social de la unidad campesina. Finalmente, no se encontró ninguna evidencia que demuestre que la política agropecuaria haya contribuido a mejorar la productividad, el bienestar social y la sustentabilidad de los recursos naturales de los productores de maíz del estado de Tlaxcala.

Evidence for ˜80-75 Ma subduction jump during Anatolide-Tauride-Armenian block accretion and ˜48 Ma Arabia-Eurasia collision in Lesser Caucasus-East Anatolia

Science.gov (United States)

Rolland, Yann; Perincek, Dogan; Kaymakci, Nuretdin; Sosson, Marc; Barrier, Eric; Avagyan, Ara

2012-05-01

Orogens formed by a combination of subduction and accretion are featured by a short-lived collisional history. They preserve crustal geometries acquired prior to the collisional event. These geometries comprise obducted oceanic crust sequences that may propagate somewhat far away from the suture zone, preserved accretionary prism and subduction channel at the interplate boundary. The cessation of deformation is ascribed to rapid jump of the subduction zone at the passive margin rim of the opposite side of the accreted block. Geological investigation and 40Ar/39Ar dating on the main tectonic boundaries of the Anatolide-Tauride-Armenian (ATA) block in Eastern Turkey, Armenia and Georgia provide temporal constraints of subduction and accretion on both sides of this small continental block, and final collisional history of Eurasian and Arabian plates. On the northern side, 40Ar/39Ar ages give insights for the subduction and collage from the Middle to Upper Cretaceous (95-80 Ma). To the south, younger magmatic and metamorphic ages exhibit subduction of Neotethys and accretion of the Bitlis-Pütürge block during the Upper Cretaceous (74-71 Ma). These data are interpreted as a subduction jump from the northern to the southern boundary of the ATA continental block at 80-75 Ma. Similar back-arc type geochemistry of obducted ophiolites in the two subduction-accretion domains point to a similar intra-oceanic evolution prior to accretion, featured by slab steepening and roll-back as for the current Mediterranean domain. Final closure of Neotethys and initiation of collision with Arabian Plate occurred in the Middle-Upper Eocene as featured by the development of a Himalayan-type thrust sheet exhuming amphibolite facies rocks in its hanging-wall at c. 48 Ma.

DaMaSCUS-CRUST: Dark Matter Simulation Code for Underground Scatterings - Crust Edition

Science.gov (United States)

Emken, Timon; Kouvaris, Chris

2018-03-01

DaMaSCUS-CRUST determines the critical cross-section for strongly interacting DM for various direct detection experiments systematically and precisely using Monte Carlo simulations of DM trajectories inside the Earth's crust, atmosphere, or any kind of shielding. Above a critical dark matter-nucleus scattering cross section, any terrestrial direct detection experiment loses sensitivity to dark matter, since the Earth crust, atmosphere, and potential shielding layers start to block off the dark matter particles. This critical cross section is commonly determined by describing the average energy loss of the dark matter particles analytically. However, this treatment overestimates the stopping power of the Earth crust; therefore, the obtained bounds should be considered as conservative. DaMaSCUS-CRUST is a modified version of DaMaSCUS (ascl:1706.003) that accounts for shielding effects and returns a precise exclusion band.

Non-economic determinants of structural transformations in Małopolska agriculture

Directory of Open Access Journals (Sweden)

Maciej Basaj

2009-01-01

Full Text Available In the article results of the research conducted in 2008 among farmers in two districts located in northern part of the Małopolska voivodeship have been presented. The aim of the article is the presentation of farmers’ opinions and attitudes against accomplishing structural alternations in their vicinity. Getting to know farmers’ intentions against the future of their farms, and also getting to know their estimations about the future of their farms in the vicinity can have particular significance in the prognosis and program of further development of rural areas – especially in such a region, with a big agrarian overpopulation as the Małopolska.

Limiares: Histoire( s) du cinéma de Jean-Luc Godard

OpenAIRE

Gervaiseau, Henri

2006-01-01

Neste artigo apresentamos a série videográfica Histoire(s) du cinéma, de Jean Luc Godard, apontamos as suas principais características, e efetuamos um primeiro exame da ordenação dos seus dois primeiros episódios. Discutimos de que modo Godard estabelece, nesta obra, uma trama poética de relações entre a história do século XX; a história do cinema e a sua própria estória enquanto sujeito enunciador. This article provides an introduction to the video series Histoire( s) du cinéma de Jean Lu...

Characteristics of halo current in JT-60U

International Nuclear Information System (INIS)

Neyatani, Y.; Nakamura, Y.; Yoshino, R.; Hatae, T.

1999-01-01

Halo currents and their toroidal peaking factor (TPF) have been measured in JT-60U by Rogowski coil type halo current sensors. The electron temperature in the halo region was around 10 eV at 1 ms before the timing of the maximum halo current. The maximum TPF*I h /I p0 was 0.52 in the operational range of I p = 0.7 ∼ 1.8 MA, B T = 2.2 ∼ 3.5 T, including ITER design parameters of κ > 1.6 and q 95 = 3, which was lower than that of the maximum value of ITER data base (0.75). The magnitude of halo currents tended to decrease with the increase in stored energy just before the energy quench and with the line integrated electron density at the time of the maximum halo current. A termination technique in which the current channel remains stationary was useful to avoid halo current generation. Intense neon gas puffing during the VDE was effective for reducing the halo currents. (author)

Characteristics of halo current in JT-60U

International Nuclear Information System (INIS)

Neyatani, Y.; Nakamura, Y.; Yoshino, R.; Hatae, T.

2001-01-01

Halo currents and their toroidal peaking factor (TPF) have been measured in JT-60U by Rogowski coil type halo current sensors. The electron temperature in the halo region was around 10 eV at 1 ms before the timing of the maximum halo current. The maximum TPF *I h /I p0 was 0.52 in the operational range of I p =0.7∼1.8MA, B T =2.2∼3.5T, including ITER design parameters of κ>1.6 and q 95 =3, which was lower than that of the maximum value of ITER data base (0.75). The magnitude of halo currents tended to decrease with the increase in stored energy just before the energy quench and with the line integrated electron density at the time of the maximum halo current. A termination technique in which the current channel remains stationary was useful to avoid halo current generation. Intense neon gas puffing during the VDE was effective for reducing the halo currents. (author)

The activities of the IAEA laboratories Vienna. Annual report - 1980

International Nuclear Information System (INIS)

Taylor, C.B.G.

1982-03-01

The report outlines the activities of the laboratory of the International Atomic Energy Agency at Seibersdorf in the province of Lower Austria. The report covers the following sections of the laboratory: chemistry, medical applications, dosimetry, soil science, entomology, plant breeding, electronics and measurement laboratory, isotope hydrology and the safeguards analytical laboratory. The extension to the main laboratory buildings - a new wing for medical applications and dosimetry - was fitted out and fully integrated into the laboratory by the end of the year. In July 1980 the high-level cobalt-60 dosimetry equipment (a teletherapy unit) was transferred from the old IAEA headquarters building in the centre of Vienna and installed in a specially designed annex to the new wing. A successful 8 week training course was given in the agriculture laboratory and arrangements were made for several of the course members to stay on as research fellows for several months after the course had ended

Laboratory and wild-derived mice with multiple loci for production of xenotropic murine leukemia virus.

Science.gov (United States)

Kozak, C A; Hartley, J W; Morse, H C

1984-07-01

Mendelian segregation analysis was used to define genetic loci for the induction of infectious xenotropic murine leukemia virus in several laboratory and wild-derived mice. MA/My mice contain two loci for xenotropic virus inducibility, one of which, Bxv -1, is the only induction locus carried by five other inbred strains. The second, novel MA/My locus, designated Mxv -1, is unlinked to Bxv -1 and shows a lower efficiency of virus induction. The NZB mouse carries two induction loci; both are distinct from Bxv -1 since neither is linked to the Pep-3 locus on chromosome 1. Finally, one partially inbred strain derived from the wild Japanese mouse, Mus musculus molossinus, carries multiple (at least three) unlinked loci for induction of xenotropic virus. Although it is probable that inbred strains inherited xenotropic virus inducibility from Japanese mice, our data suggest that none of the induction loci carried by this particular M. m. molossinus strain are allelic with Bxv -1.

Motion of the Rivera plate since 10 Ma relative to the Pacific and North American plates and the mantle

Science.gov (United States)

DeMets, Charles; Traylen, Stephen

2000-03-01

To better understand the influence of Rivera plate kinematics on the geodynamic evolution of western Mexico, we use more than 1400 crossings of seafloor spreading magnetic lineations along the Pacific-Rivera rise and northern Mathematician ridge to solve for rotations of the Rivera plate relative to the underlying mantle and the Pacific and North American plates at 14 times since 9.9 Ma. Our comparison of magnetic anomaly crossings from the undeformed Pacific plate to their counterparts on the Rivera plate indicates that significant areas of the Rivera plate have deformed since 9.9 Ma. Dextral shear along the southern edge of the plate from 3.3-2.2 Ma during a regional plate boundary reorganization deformed the Rivera plate farther into its interior than previously recognized. In addition, seafloor located north of two rupture zones within the Rivera plate sutured to North America after 1.5 Ma. Anomaly crossings from these two deformed regions thus cannot be used to reconstruct motion of the Rivera plate. Finite rotations that best reconstruct Pacific plate anomaly crossings onto their undeformed counterparts on the Rivera plate yield stage spreading rates that decrease gradually by 10% between 10 and 3.6 Ma, decrease rapidly by 20% after ˜3.6 Ma, and recover after 1 Ma. The slowdown in Pacific-Rivera seafloor spreading at 3.6 Ma coincided with the onset of dextral shear across the then-incipient southern boundary of the Rivera plate with the Pacific plate. The available evidence indicates that the Rivera plate has been an independent microplate since at least 10 Ma, contrary to published assertions that it fragmented from the Cocos plate at ˜5 Ma. Motion of the Rivera plate relative to North America has changed significantly since 10 Ma, in concert with significant changes in Pacific-Rivera motion. A significant and robust feature of Rivera-North America motion not previously recognized is the cessation of margin-normal convergence and thus subduction from 2

EFFECTIVENESS OF M.A. EPM PROGRAM LAUNCHED THROUGH DISTANCE EDUCATION SYSTEM OF ALLAMA IQBAL OPEN UNIVERSITY ISLAMABAD

Directory of Open Access Journals (Sweden)

Syed Manzoor HUSSAIN SHAH

2014-10-01

Full Text Available The study focus the effectiveness of the M.A EPM progam launched through distance education system of AIOU. For this purpose the performance of heads of educational institutions with and without M.A EPM degree was analyzed keeping in view different major aspects i.e. planning strategies, managerial approaches, coordination, administration and use of financial resources. The population of the study consisted of heads of educational institutions with and without MA EPM degree in Punjab. It was found that the performance of heads with EPM degree was better while planning strategies, management, coordination, following govt. policies, preparing annual budget and using financial resources as compared to heads without EPM degree. On the basis of the conclusions of the study it was recommended that MA EPM degree may be declared compulsory for heads of educational institutions. All the universities may start MA EPM degree to fulfill the requirements of working and professional educational planners and managers of the country.

Liner velocity, current, and symmetry measurements on the 32 MA flux compression generator experiment ALT-1

CERN Document Server

Clark, D A; Rodríguez, G; Tabaka, L J

2001-01-01

Summary form only given, as follows. A flux compression generator based pulse power system, designed, built, and fielded by a Russian team at the All Russian Scientific Research Institute of Experimental Physics (VNIIEF), was used to successfully drive an aluminum liner to velocities greater than 10 km/sec. The experiment objective was to demonstrate performance of a precision liner implosion at Atlas current of 30 MA or greater. Diagnostics to measure liner performance were an essential part of the experiment. An experimental team from Los Alamos National Laboratory (LANL) provided a suite of diagnostics to measure liner performance. Three diagnostics were fielded. 1. a velocity interferometer (VISAR) to continuously measure the liner inner surface velocity from throughout the entire range of travel. 2. Two Faraday rotation devices to measure liner current during the implosion. 3. Sixteen fiber optic impact pins to record liner impact time and provide axial and azimuthal symmetry information. All diagnostics...

A Precise 6 Ma Start Date for Fluvial Incision of the Northeastern Colorado Plateau Canyonlands

Science.gov (United States)

Thomson, S. N.; Soreghan, G. S.; Reiners, P. W.; Peyton, S. L.; Murray, K. E.

2015-12-01

Outstanding questions regarding late Cenozoic Colorado Plateau landscape evolution include: (1) the relative roles of isostatic rebound as result Colorado River incision versus longer-term geodynamic processes in driving overall rock uplift of the plateau; and (2) whether incision was triggered by river integration or by a change in deep-seated mantle lithosphere dynamics. A key to answering these questions is to date more precisely the onset of incision to refine previous estimates of between 6 and 10 Ma. We present new low-temperature thermochronologic results from bedrock and deep borehole samples in the northeastern Colorado Plateau to show that rapid river incision began here at 6 Ma (5.93±0.66 Ma) with incision rates increasing from 15-50 m/Myr to 160-200 m/Myr. The onset time is constrained independently by both inverse time-temperature modeling and by the break-in-slope in fission track age-elevation relationships. This new time constraint has several important implications. First, the coincidence in time with 5.97-5.3 Ma integration of the lower Colorado River through the Grand Canyon to the Gulf of California strongly favors downstream river integration triggering carving of the canyonlands of the upper Colorado River system. Second, it implies integration of the entire Colorado River system in less than 2 million years. Third, rock uplift of the plateau driven by the flexural isostatic response to river incision is restricted to just the last 6 Ma, as is associated increased sediment budget. Fourth, incision starting at 6 Ma means that previous estimates of upper Colorado River incision rates based on 10-12 Ma basalt datum levels are too low. This also changes the dependency of measured time interval on incision rate from a non-steady-state negative power-law dependence (exponent of -0.24) to a near steady-state dependence (exponent of 0.07) meaning that long-term upper Colorado river incision rates can provide a reliable proxy for rock uplift rates.

Strategies for laboratory cost containment and for pathologist shortage: centralised pathology laboratories with microwave-stimulated histoprocessing and telepathology.

Science.gov (United States)

Leong, Anthony S Y; Leong, F Joel W M

2005-02-01

The imposition of laboratory cost containment, often from external forces, dictates the necessity to develop strategies to meet laboratory cost savings. In addition, the national and worldwide shortage of anatomical pathologists makes it imperative to examine our current practice and laboratory set-ups. Some of the strategies employed in other areas of pathology and laboratory medicine include improvements in staff productivity and the adoption of technological developments that reduce manual intervention. However, such opportunities in anatomical pathology are few and far between. Centralisation has been an effective approach in bringing economies of scale, the adoption of 'best practices' and the consolidation of pathologists, but this has not been possible in anatomical pathology because conventional histoprocessing takes a minimum of 14 hours and clinical turnaround time requirements necessitate that the laboratory and pathologist be in proximity and on site. While centralisation of laboratories for clinical chemistry, haematology and even microbiology has been successful in Australia and other countries, the essential requirements for anatomical pathology laboratories are different. In addition to efficient synchronised courier networks, a method of ultra-rapid tissue processing and some expedient system of returning the prepared tissue sections to the remote laboratory are essential to maintain the turnaround times mandatory for optimal clinical management. The advent of microwave-stimulated tissue processing that can be completed in 30-60 minutes and the immediate availability of compressed digital images of entire tissue sections via telepathology completes the final components of the equation necessary for making centralised anatomical pathology laboratories a reality.

Zakrzepowa plamica małopłytkowa – diagnostyka i leczenie

Directory of Open Access Journals (Sweden)

Jolanta Korsak

2013-12-01

Full Text Available Zakrzepowa plamica małopłytkowa (thrombotic thrombocytopenic purpura, TTP początkowo charakteryzowała się pentadą objawów: małopłytkowością, niedokrwistością hemolityczną mikroangiopatyczną, zaburzeniami układu nerwowego, niewydolnością nerek i gorączką. Jednak u 35% chorych z rozpoznaniem TTP nie stwierdza się wszyst‑ kich tych dolegliwości: nie występują u nich objawy neurologiczne, zaburzenia funkcji nerek oraz gorączka. Obec‑ nie zakrzepową plamicę małopłytkową rozpoznaje się na podstawie małopłytkowości i niedokrwistości mikroangiopatycznej. Diagnostyka obejmuje badanie morfologiczne krwi obwodowej wraz z rozmazem, badanie czynności nerek i oznaczenie aktywności LDH. Pomocne w rozpoznaniu jest oznaczenie aktywności metaloprote‑ azy ADAMTS13 i miana przeciwciał anty-ADAMTS13. W terapii w pierwszym rzucie stosuje się plazmaferezę lecz‑ niczą – powinna ona zostać przeprowadzona nawet wtedy, gdy diagnoza jest niepewna. Plazmafereza usuwa mul‑ timery ULvWF i nabyte przeciwciała skierowane przeciw ADAMTS13. Przetoczenie osocza nie jest tak efektywne jak plazmafereza, lecz może być stosowane tymczasowo. Efekt leczenia oceniany jest na podstawie unormowa‑ nia się aktywności LDH oraz ustąpienia małopłytkowości, niedokrwistości i zmian neurologicznych. Inną możli‑ wością terapeutyczną jest podawanie glikokortykosteroidów oraz immunoglobulin. U niektórych chorych korzystne może być wykonanie splenektomii. Ostatnio stosuje się także rytuksymab – powoduje on redukcję miana inhibitora ADAMTS13 i wzrost aktywności enzymu. Po leczeniu rytuksymabem odnotowano remisje kliniczne w przypad‑ kach, w których zawiodły inne metody terapii.

MaMiCo: Transient multi-instance molecular-continuum flow simulation on supercomputers

Science.gov (United States)

Neumann, Philipp; Bian, Xin

2017-11-01

We present extensions of the macro-micro-coupling tool MaMiCo, which was designed to couple continuum fluid dynamics solvers with discrete particle dynamics. To enable local extraction of smooth flow field quantities especially on rather short time scales, sampling over an ensemble of molecular dynamics simulations is introduced. We provide details on these extensions including the transient coupling algorithm, open boundary forcing, and multi-instance sampling. Furthermore, we validate the coupling in Couette flow using different particle simulation software packages and particle models, i.e. molecular dynamics and dissipative particle dynamics. Finally, we demonstrate the parallel scalability of the molecular-continuum simulations by using up to 65 536 compute cores of the supercomputer Shaheen II located at KAUST. Program Files doi:http://dx.doi.org/10.17632/w7rgdrhb85.1 Licensing provisions: BSD 3-clause Programming language: C, C++ External routines/libraries: For compiling: SCons, MPI (optional) Subprograms used: ESPResSo, LAMMPS, ls1 mardyn, waLBerla For installation procedures of the MaMiCo interfaces, see the README files in the respective code directories located in coupling/interface/impl. Journal reference of previous version: P. Neumann, H. Flohr, R. Arora, P. Jarmatz, N. Tchipev, H.-J. Bungartz. MaMiCo: Software design for parallel molecular-continuum flow simulations, Computer Physics Communications 200: 324-335, 2016 Does the new version supersede the previous version?: Yes. The functionality of the previous version is completely retained in the new version. Nature of problem: Coupled molecular-continuum simulation for multi-resolution fluid dynamics: parts of the domain are resolved by molecular dynamics or another particle-based solver whereas large parts are covered by a mesh-based CFD solver, e.g. a lattice Boltzmann automaton. Solution method: We couple existing MD and CFD solvers via MaMiCo (macro-micro coupling tool). Data exchange and

Development of a Hydronic Rooftop Unit-HyPak-MA

Energy Technology Data Exchange (ETDEWEB)

Lee, Eric; Berman, Mark

2009-11-14

The majority of U.S. commercial floor space is cooled by rooftop HVAC units (RTUs). RTU popularity derives chiefly from their low initial cost and relative ease of service access without disturbing building occupants. Unfortunately, current RTUs are inherently inefficient due to a combination of characteristics that unnecessarily increase cooling loads and energy use. 36% percent of annual U.S. energy, and two-thirds of electricity, is consumed in and by buildings. Commercial buildings consume approximately 4.2 quads of energy each year at a cost of $230 billion per year, with HVAC equipment consuming 1.2 quads of electricity. More than half of all U.S. commercial floor space is cooled by packaged HVAC units, most of which are rooftop units (RTUs). Inefficient RTUs create an estimated 3.5% of U.S. CO{sub 2} emissions, thus contributing significantly to global warming5. Also, RTUs often fail to maintain adequate ventilation air and air filtration, reducing indoor air quality. This is the second HyPak project to be supported by DOE through NETL. The prior project, referred to as HyPak-1 in this report, had two rounds of prototype fabrication and testing as well as computer modeling and market research. The HyPak-1 prototypes demonstrated the high performance capabilities of the HyPak concept, but made it clear that further development was required to reduce heat exchanger cost and improve system reliability before HyPak commercialization can commence. The HyPak-1 prototypes were limited to about 25% ventilation air fraction, limiting performance and marketability. The current project is intended to develop a 'mixed-air' product that is capable of full 0-100% modulation in ventilation air fraction, hence it was referred to as HyPak-MA in the proposal. (For simplicity, the -MA has been dropped when referencing the current project.) The objective of the HyPak Project is to design, develop and test a hydronic RTU that provides a quantum improvement over

Organising and learning experiences of the first semester MA Program ePedagogy / Visual Knowledge Building

NARCIS (Netherlands)

Jaap Jansen

2006-01-01

This paper will discuss the process of the MA program ePedagogy / Visual Knowledge Building during the first semester of the academic year 2005 – 2006. This MA program is a joint venture between the Universities of Helsinki, Hamburg and INHOLLAND. This publication will discuss and evaluate the

Overview of the SDSS-IV MaNGA Survey: Mapping nearby Galaxies at Apache Point Observatory

NARCIS (Netherlands)

Bundy, Kevin; Bershady, Matthew A.; Law, David R.; Yan, Renbin; Drory, Niv; MacDonald, Nicholas; Wake, David A.; Cherinka, Brian; Sánchez-Gallego, José R.; Weijmans, Anne-Marie; Thomas, Daniel; Tremonti, Christy; Masters, Karen; Coccato, Lodovico; Diamond-Stanic, Aleksandar M.; Aragón-Salamanca, Alfonso; Avila-Reese, Vladimir; Badenes, Carles; Falcón-Barroso, Jésus; Belfiore, Francesco; Bizyaev, Dmitry; Blanc, Guillermo A.; Bland-Hawthorn, Joss; Blanton, Michael R.; Brownstein, Joel R.; Byler, Nell; Cappellari, Michele; Conroy, Charlie; Dutton, Aaron A.; Emsellem, Eric; Etherington, James; Frinchaboy, Peter M.; Fu, Hai; Gunn, James E.; Harding, Paul; Johnston, Evelyn J.; Kauffmann, Guinevere; Kinemuchi, Karen; Klaene, Mark A.; Knapen, Johan H.; Leauthaud, Alexie; Li, Cheng; Lin, Lihwai; Maiolino, Roberto; Malanushenko, Viktor; Malanushenko, Elena; Mao, Shude; Maraston, Claudia; McDermid, Richard M.; Merrifield, Michael R.; Nichol, Robert C.; Oravetz, Daniel; Pan, Kaike; Parejko, John K.; Sanchez, Sebastian F.; Schlegel, David; Simmons, Audrey; Steele, Oliver; Steinmetz, Matthias; Thanjavur, Karun; Thompson, Benjamin A.; Tinker, Jeremy L.; van den Bosch, Remco C. E.; Westfall, Kyle B.; Wilkinson, David; Wright, Shelley; Xiao, Ting; Zhang, Kai

We present an overview of a new integral field spectroscopic survey called MaNGA (Mapping Nearby Galaxies at Apache Point Observatory), one of three core programs in the fourth-generation Sloan Digital Sky Survey (SDSS-IV) that began on 2014 July 1. MaNGA will investigate the internal kinematic

Veinticinco años de mejoramiento en los sistemas de maíz en Centroamérica: logros y estrategias hacia el año 2000

Directory of Open Access Journals (Sweden)

Hugo C\\u00F3rdova

2002-01-01

Full Text Available La ciencia y la tecnología constituyen la brecha más importante entre la pobreza y la prosperidad. Durante el último cuarto de siglo, la introducción de prácticas tecnológicas basadas en la ciencia, han ayudado a muchos países en desarrollo a alcanzar una relación favorable entre la producción de alimentos y el crecimiento de la población. En Centroamé- rica y El Caribe el mejoramiento genético del maíz ha contribuido a la liberación de aproximadamente 80 cultivares que han sido multiplicados y distribuidos por una industria de semillas dinámica y progresista. Estos cultivares, asociados con prácticas agronómicas apropiadas, han permitido aumentar la productividad del maíz en la región, lo que ha representado el incremento del rendimiento en un 60% aproximadamente, siendo este aspecto más significativo en países como El Salvador y Guatemala que duplicaron los rendimientos y mejoraron el autoabastecimiento de maíz. Los cultivares tolerantes al achaparramiento y adaptados a condiciones de humedad limitada, están desempeñando un papel muy importante en el mantenimiento sustentable de la producción. La liberaci ón de híbridos modernos de maíz, tolerantes a factores adversos, bióticos y abióticos, contribuirá a reducir las pérdidas postcosecha. El mejor entendimiento de algunos aspectos fisiológicos correlacionados con el rendimiento y la incorporaci ón de índices de selección más eficientes en las metodolog ías de mejoramiento para ambientes adversos, han mejorado las técnicas de selección.

Paleomagnetic study of 1765 Ma dyke swarm from the Singhbhum Craton: Implications to the paleogeography of India

Science.gov (United States)

Shankar, Ravi; Srinivasa Sarma, D.; Ramesh Babu, N.; Parashuramulu, V.

2018-05-01

We report the first key paleopole as a result of paleomagnetic study on a precisely dated 1765.3 ± 1.0 Ma WNW-ESE trending dyke swarm from Singhbhum Craton. This pole has been used in this study to propose the paleogeographic reconstruction of India with Baltica Craton and North China Craton. Incremental alternating field (AF) and thermal demagnetization, isolated high coercivity components with north to north-westerly declination and shallow negative inclination from 9 sampling sites which are representing different individual dykes. The primary origin of the ChRM is supported by the positive baked contact test. The WNW-ESE trending dykes yield a mean paleomagnetic direction with a declination = 329.2° and an inclination = -22.8° (k = 31.6; α95 = 9.3°). The positive bake contact test proves the primary nature of remanence. The pole position of Singhbhum Craton at 1765 Ma is 45°N, 311°E (dp = 5.2 and dm = 9.9). Paleogeographic reconstruction at ca. 1770 Ma, supported by geological, tectonic and metallogenic evidences indicate that the Baltica Craton and India linkage can be stable for at least ∼370 Ma (∼1770-1400 Ma). There is also reasonable evidence in support of India-North China Craton spatial proximity at ∼1770 Ma.

Measurements of {sup 60}Co in spoons activated by neutrons during the JCO criticality accident at Tokai-mura in 1999

Energy Technology Data Exchange (ETDEWEB)

Gasparro, J.; Hult, M. E-mail: mikael.hult@irmm.jrc.be; Komura, K.; Arnold, D.; Holmes, L.; Johnston, P.N.; Laubenstein, M.; Neumaier, S.; Reyss, J.-L.; Schillebeeckx, P.; Tagziria, H.; Van Britsom, G.; Vasselli, R

2004-07-01

Neutron activated items from the vicinity of the place where the JCO criticality accident occurred have been used to determine the fluence of neutrons around the facility and in nearby residential areas. By using underground laboratories for measuring the activation products, it is possible to extend the study to also cover radionuclides with very low activities from long-lived radionuclides. The present study describes {gamma}-ray spectrometry measurements undertaken in a range of underground laboratories for the purpose of measuring {sup 60}Co more than 2 years after the criticality event. The measurements show that neutron fluence determined from {sup 60}Co activity is in agreement with previous measurements using the short-lived radionuclides {sup 51}Cr and {sup 59}Fe. Limits on contamination of the samples with {sup 60}Co are evaluated and shown to not greatly affect the utility of neutron fluence determinations using {sup 60}Co activation.

Precio del maíz en México y ley del precio único

Directory of Open Access Journals (Sweden)

Miguel Ángel Martínez Damián

2017-01-01

Full Text Available El abasto de maíz debe cubrirse con importaciones de Estados Unidos de América ( ee. uu. . Si dicho intercambio es de libre comercio, entonces debe observarse la ley del precio único ( lpu . Bajo un modelo vectorial de corrección de error, se examina la lpu para el precio de maíz en México y ee. uu . Los resultados si bien rechazan estadísticamente la lpu , el vector cointegrante estimado es de signo y magnitud acorde con la lpu , dicho vector implica la existencia de una combinación lineal estacionaria que provee evidencia de integración de mercados. Secundariamente se encuentra que el precio de maíz en México es causado, en el sentido de Granger, por el precio en ee. uu. y que dicho precio no es exógeno al vector examinado.

Gelatin–PMVE/MA composite scaffold promotes expansion of embryonic stem cells

International Nuclear Information System (INIS)

Chhabra, Hemlata; Gupta, Priyanka; Verma, Paul J.; Jadhav, Sameer; Bellare, Jayesh R.

2014-01-01

We introduce a new composite scaffold of gelatin and polymethyl vinyl ether-alt-maleic anhydride (PMVE/MA) for expansion of embryonic stem cells (ESCs) in an in vitro environment. To optimize the scaffold, we prepared a gelatin scaffold (G) and three composite scaffolds namely GP-1, GP-2, and GP-3 with varying PMVE/MA concentrations (0.2–1%) and characterized them by scanning electron microscopy (SEM), swelling study, compression testing and FTIR. SEM micrographs revealed interconnected porous structure in all the scaffolds. The permissible hemolysis ratio and activation of platelets by scaffolds confirmed the hemocompatibility of scaffolds. Initial biocompatibility assessment of scaffolds was conducted using hepatocarcinoma (Hep G2) cells and adhesion, proliferation and infiltration of Hep G2 cells in depth of scaffolds were observed, proving the scaffold's biocompatibility. Further Oct4B2 mouse embryonic stem cells (mESCs), which harbor a green fluorescence protein transgene under regulatory control of the Oct4 promotor, were examined for expansion on scaffolds with MTT assay. The GP-2 scaffold demonstrated the best cell proliferation and was further explored for ESC adherence and infiltration in depth (SEM and confocal), and pluripotent state of mESCs was assessed with the expression of Oct4-GFP and stage-specific embryonic antigen-1 (SSEA-1). This study reports the first demonstration of biocompatibility of gelatin–PMVE/MA composite scaffold and presents this scaffold as a promising candidate for embryonic stem cell based tissue engineering. - Highlights: • Composite scaffolds of gelatin and PMVE/MA were prepared by freeze-drying method. • SEM micrographs showed porous structure in all scaffolds of varying pore dimension. • GP-2 composite exhibited better cellular response in comparison to other scaffolds. • mESCs proliferated and expressed Oct-4 and SSEA-1, when cultured on GP-2 scaffold

Gelatin–PMVE/MA composite scaffold promotes expansion of embryonic stem cells

Energy Technology Data Exchange (ETDEWEB)

Chhabra, Hemlata [Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai (India); Gupta, Priyanka [Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai (India); IITB-Monash Research Academy, Mumbai (India); Department of Chemical Engineering, Monash University, Melbourne (Australia); Verma, Paul J. [Turretfield Research Centre, South Australian Research and Development Institute, Rosedale, South Australia (Australia); Jadhav, Sameer; Bellare, Jayesh R. [Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai (India)

2014-04-01

We introduce a new composite scaffold of gelatin and polymethyl vinyl ether-alt-maleic anhydride (PMVE/MA) for expansion of embryonic stem cells (ESCs) in an in vitro environment. To optimize the scaffold, we prepared a gelatin scaffold (G) and three composite scaffolds namely GP-1, GP-2, and GP-3 with varying PMVE/MA concentrations (0.2–1%) and characterized them by scanning electron microscopy (SEM), swelling study, compression testing and FTIR. SEM micrographs revealed interconnected porous structure in all the scaffolds. The permissible hemolysis ratio and activation of platelets by scaffolds confirmed the hemocompatibility of scaffolds. Initial biocompatibility assessment of scaffolds was conducted using hepatocarcinoma (Hep G2) cells and adhesion, proliferation and infiltration of Hep G2 cells in depth of scaffolds were observed, proving the scaffold's biocompatibility. Further Oct4B2 mouse embryonic stem cells (mESCs), which harbor a green fluorescence protein transgene under regulatory control of the Oct4 promotor, were examined for expansion on scaffolds with MTT assay. The GP-2 scaffold demonstrated the best cell proliferation and was further explored for ESC adherence and infiltration in depth (SEM and confocal), and pluripotent state of mESCs was assessed with the expression of Oct4-GFP and stage-specific embryonic antigen-1 (SSEA-1). This study reports the first demonstration of biocompatibility of gelatin–PMVE/MA composite scaffold and presents this scaffold as a promising candidate for embryonic stem cell based tissue engineering. - Highlights: • Composite scaffolds of gelatin and PMVE/MA were prepared by freeze-drying method. • SEM micrographs showed porous structure in all scaffolds of varying pore dimension. • GP-2 composite exhibited better cellular response in comparison to other scaffolds. • mESCs proliferated and expressed Oct-4 and SSEA-1, when cultured on GP-2 scaffold.

DNA fingerprinting of the NCI-60 cell line panel.

Science.gov (United States)

Lorenzi, Philip L; Reinhold, William C; Varma, Sudhir; Hutchinson, Amy A; Pommier, Yves; Chanock, Stephen J; Weinstein, John N

2009-04-01

The National Cancer Institute's NCI-60 cell line panel, the most extensively characterized set of cells in existence and a public resource, is frequently used as a screening tool for drug discovery. Because many laboratories around the world rely on data from the NCI-60 cells, confirmation of their genetic identities represents an essential step in validating results from them. Given the consequences of cell line contamination or misidentification, quality control measures should routinely include DNA fingerprinting. We have, therefore, used standard DNA microsatellite short tandem repeats to profile the NCI-60, and the resulting DNA fingerprints are provided here as a reference. Consistent with previous reports, the fingerprints suggest that several NCI-60 lines have common origins: the melanoma lines MDA-MB-435, MDA-N, and M14; the central nervous system lines U251 and SNB-19; the ovarian lines OVCAR-8 and OVCAR-8/ADR (also called NCI/ADR); and the prostate lines DU-145, DU-145 (ATCC), and RC0.1. Those lines also show that the ability to connect two fingerprints to the same origin is not affected by stable transfection or by the development of multidrug resistance. As expected, DNA fingerprints were not able to distinguish different tissues-of-origin. The fingerprints serve principally as a barcodes.

New compact hohlraum configuration research at the 1.7 MA Z-pinch generator

Energy Technology Data Exchange (ETDEWEB)

Kantsyrev, V. L., E-mail: victor@unr.edu; Shrestha, I. K.; Esaulov, A. A.; Safronova, A. S.; Shlyaptseva, V. V.; Osborne, G. C.; Astanovitsky, A. L.; Weller, M. E.; Stafford, A.; Schultz, K. A.; Cooper, M. C. [Physics Department, University of Nevada, Reno, NV 89557 (United States); Chuvatin, A. S. [Laboratorie de Physique des Plasmas, Ecole Polytechnique, 91128 Palaiseau (France); Rudakov, L. I. [Icarus Research Inc., P.O. Box 30780, Bethesda, MD 20824-0780 (United States); Velikovich, A. L. [Plasma Physics Division, Naval Research Laboratory, Washington, DC 20375 (United States); Cuneo, M. E.; Jones, B.; Vesey, R. A. [Sandia National Laboratories, Albuquerque, NM 87110 (United States)

2014-12-15

A new compact Z-pinch x-ray hohlraum design with parallel-driven x-ray sources was experimentally demonstrated in a full configuration with a central target and tailored shine shields (to provide a symmetric temperature distribution on the target) at the 1.7 MA Zebra generator. This presentation reports on the joint success of two independent lines of research. One of these was the development of new sources – planar wire arrays (PWAs). PWAs turned out to be a prolific radiator. Another success was the drastic improvement in energy efficiency of pulsed-power systems, such as the Load Current Multiplier (LCM). The Zebra/LCM generator almost doubled the plasma load current to 1.7 MA. The two above-mentioned innovative approaches were used in combination to produce a new compact hohlraum design for ICF, as jointly proposed by SNL and UNR. Good agreement between simulated and measured radiation temperature of the central target is shown. Experimental comparison of PWAs with planar foil liners (PFL) - another viable alternative to wire array loads at multi-MA generators show promising data. Results of research at the University of Nevada Reno allowed for the study of hohlraum coupling physics at University-scale generators. The advantages of new hohlraum design applications for multi-MA facilities with W or Au double PWAs or PFL x-ray sources are discussed.

Review of JT-60U experimental results from January to October, 1992

International Nuclear Information System (INIS)

1993-03-01

Heating experiments have been carried out in JT-60U with plasma current up to 4 MA, toroidal field up to 4.2 T and neutral beam heating power of 30 MW. H-mode was observed at high toroidal field of 4.2 T. Confinement improvement factor of up to 1.6 over the L-mode scaling has been obtained during continuous ELMy phase at 4.2 T, 2.7 MA and an injection power of 25 MW. Confinement enhancement of 2.2 has been obtained. At plasma current of 3.5 MA, diamagnetic stored energy of 7.7 MJ and energy confinement time of 0.36 s have been obtained. In the discharges with high poloidal beta exhibit, high ion temperatures of 38 keV, electron temperatures of 12 keV, maximum diamagnetic stored energy of 6.1 MJ and neutron yield of 2.8 x 10 16 s -1 were obtained. Schemes to avoid locked modes and disruptions have been checked experimentally. Divertor measurement indicates that high q, high density operation is favorable for divertor heat handling. Quantitative analysis of divertor spectroscopy data indicates that the carbon production rate at the divertor plate is explained by deuterium, oxygen and carbon sputtering. Toroidal ripple loss power of NB-injected fast ions to the first wall was investigated by using an infrared TV camera. Absolute values of the ripple loss power and dependence on plasma parameters were consistent with values calculated by an orbit following Monte-Carlo code. In the LHCD area, the linear dispersion relation and accessibility condition for LH wave were experimentally validated. Furthermore, the power directly lost via high energy electron was shown to scale as the slowing down time. Current drive of 400 kA was realized with tangential NB. ICRF experiments using two new antennas started. Sawtooth stabilization at a high n-bar e /P tot value was achieved. (J.P.N.)

Under-performance of listed companies? Real earnings management and M&A: Chinese empirical evidence

Directory of Open Access Journals (Sweden)

Ziqiao Zhang

2015-04-01

Full Text Available Purpose: The purpose of this paper is to examine whether acquiring firms attempt to adopt real earnings management strategy to upward reported earnings in the period of M&A announcement and provide an explanation for the underperformance of post-M&A in share payment M&A affairs occurring in China’s capital market from 2008-2010. Design/methodology/approach: The author uses Roychowdhury’s(2006 methodology to measure the magnitude of real earnings management of acquiring firms in stock for stock M&A by exploiting financial date from 2006 to 2011. The methodology includes three models, which are cash ?ow from operations, production costs and discretionary expenditures, respectively. Findings: It was found that firms using stock as a financing medium exhibit significant negative abnormal cash flows and abnormal discretionary expenses yet abnormal production costs significantly positive during the current period of M&A. Moreover, it was also documented that acquiring firms use real activities manipulation to overstate earnings for the purpose of improving market confidence. Finally, a negative association was found between REM and under-performance of post-M&A. Research limitations/implications: To some extent, these results explain the puzzle of performance decline over the following period of post-M&A. Meanwhile, our study adds to prior literature that capital market pressures induce acquiring firms inflate reported earnings by manipulating real activities in stock-financed M&A occurring in China’s capital market. Practical implications: The author’s result imply that investors, analysts and regulators cannot ignore more undetectable opportunism behaviors underlying reported earnings than accrual-based earnings management and the impact on the performance of post-M&A when they use financial statements to evaluate acquiring firms. Social implications: Our study plays important role in making public policies. Furthermore, it is necessary to

Finančné due diligence: teória a prax pri M&A transakciách

OpenAIRE

Vavrovič, Maroš

2015-01-01

This thesis focuses on financial due diligence within M&A transactions. In the first part, due diligence is characterized as one of the main factors of M&A failure. Due diligence process and definition is described afterwards, as well as purpose of due diligence, various types of due diligence and position of due diligence within individual phases of M&A transaction. Furthermore, financial due diligence and its main principles are defined. Essential differences between financial due diligence...

Brookhaven National Laboratory moves to the fast lane

CERN Multimedia

2006-01-01

"The U.S. Department of Energy's energy sciences network (ESnet) continues to roll out its next-generation architecture on schedule with the March 14 completion of the Long Island Metropolitan Area Network, connecting Brookhaven National Laboratory (BNL) to the ESnet point of presente (PO) 60 miles away in New York City." (1 page)

Phenomenology of MaVaN’s Models in Reactor Neutrino Data

Directory of Open Access Journals (Sweden)

M. F. Carneiro

2013-01-01

Full Text Available Mass Varying Neutrinos (MaVaN’s mechanisms were proposed to link the neutrino mass scale with the dark energy density, addressing the coincidence problem. In some scenarios, this mass can present a dependence on the baryonic density felt by neutrinos, creating an effective neutrino mass that depends both on the neutrino and baryonic densities. In this work, we study the phenomenological consequence of MaVaN’s scenarios in which the matter density dependence is induced by Yukawa interactions of a light neutral scalar particle which couples to neutrinos and matter. Under the assumption of one mass scale dominance, we perform an analysis of KamLAND neutrino data which depends on 4 parameters: the two standard oscillation parameters, Δm0,212 and tan2θ12, and two new coefficients which parameterize the environment dependence of neutrino mass. We introduce an Earth’s crust model to compute precisely the density in each point along the neutrino trajectory. We show that this new description of density does not affect the analysis with the standard model case. With the MaVaN model, we observe a first order effect in lower density, which leads to an improvement on the data description.

Construction of helium engineering demonstration loop (HENDEL M+A) for VHTR

International Nuclear Information System (INIS)

Shimomura, Saneaki; Tanaka, Toshiyuki; Nakano, Tadasuke

1983-01-01

The mother and adapter sections of the large structural component demonstration test loop, alias Helium Engineering Demonstration Loop, for the multipurpose, high temperature gas-cooled experimental reactor were completed in March, 1982. This facility was constructed by Fuji Electric Co., Ltd. and Kawasaki Heavy Industries Ltd. as the main contractors, and by the cooperation with Mitsubishi Heavy Industries Ltd. and Ishikawajima Harima Heavy Industries Co., Ltd. The HENDEL M+A is the testing facility of the largest scale in the world, which can handle 1000 deg C, 40 kgf/cm 2 G helium at a half flow rate of one core cooling loop of the experimental reactor. With the HENDEL M+A, the demonstration tests of fuel assembly stacks, in-core structures, large flow rate and high temperature equipment are planned. The HENDEL M+A comprises two mother loops, an adapter loop, and common auxiliary systems fon measurement and control (In), refining (Mp), makeup (Mu) and cooling water (Uc). The construction and function of such main equipment as a heater, circulators and internally insulated piping are described. The progress of the construction and the main experience during the construction, the process of operation and the performance are reported. (Kako, I.)

SDSS-IV MaNGA: Probing the Kinematic Morphology–Density Relation of Early-type Galaxies with MaNGA

Science.gov (United States)

Greene, J. E.; Leauthaud, A.; Emsellem, E.; Goddard, D.; Ge, J.; Andrews, B. H.; Brinkman, J.; Brownstein, J. R.; Greco, J.; Law, D.; Lin, Y.-T.; Masters, K. L.; Merrifield, M.; More, S.; Okabe, N.; Schneider, D. P.; Thomas, D.; Wake, D. A.; Yan, R.; Drory, N.

2017-12-01

The “kinematic” morphology–density relation for early-type galaxies posits that those galaxies with low angular momentum are preferentially found in the highest-density regions of the universe. We use a large sample of galaxy groups with halo masses {10}12.5MaNGA) survey to examine whether there is a correlation between local environment and rotational support that is independent of stellar mass. We find no compelling evidence for a relationship between the angular momentum content of early-type galaxies and either local overdensity or radial position within the group at fixed stellar mass.

The front end test stand high performance H- ion source at Rutherford Appleton Laboratory.

Science.gov (United States)

Faircloth, D C; Lawrie, S; Letchford, A P; Gabor, C; Wise, P; Whitehead, M; Wood, T; Westall, M; Findlay, D; Perkins, M; Savage, P J; Lee, D A; Pozimski, J K

2010-02-01

The aim of the front end test stand (FETS) project is to demonstrate that chopped low energy beams of high quality can be produced. FETS consists of a 60 mA Penning Surface Plasma Ion Source, a three solenoid low energy beam transport, a 3 MeV radio frequency quadrupole, a chopper, and a comprehensive suite of diagnostics. This paper details the design and initial performance of the ion source and the laser profile measurement system. Beam current, profile, and emittance measurements are shown for different operating conditions.

The Authority and Charismas of Jack Ma's Leadership

Institute of Scientific and Technical Information of China (English)

陈希

2014-01-01

Jack Ma is the top manager of Ali Baba group, with a strong leadership. He mixes autocratic leadership and charismatic leadership together. The powers he used are from his position, the reward system of the company and the charismas to gain his leading power. In addition, he uses his charismas and his achievements to win the trust of the employees, which develop his leadership.

Exploring the Origin of Kinematically Irregular Galaxies with MaNGA

Science.gov (United States)

Stark, David Vincent; Bundy, Kevin; Westfall, Kyle; Bershady, Matthew; Cheung, Edmond; Soler, Juan; Brinchmann, Jarle; Abraham, Roberto; Bizyaev, Dmitry; Masters, Karen; Weijmans, Anne-Marie; Chen, Yanmei; Jin, Yifei; Drory, Niv; Lopes, Alexandre Roman; Law, David

2018-01-01

Deviations from normal rotation in galaxies may have a number of potential drivers, including tidal interactions, gas inflows/outflows, spiral structure, bar/oval distortions, or other internally generated instabilities. Thanks to new massive IFU surveys like MaNGA, we can now characterize the gas and stellar kinematics of thousands of galaxies in the local universe, enabling statistical analyses on the frequency of disturbed kinematics, their origin, and their impact on their host galaxies. We present a census of kinematics in MaNGA using a modified version of the Radon transform to map radial variations in kinematic position angles (PA). We discuss the frequency of kinematically irregular disks, and describe commonly observed patterns in radial PA profiles. In order to constrain the drivers of these kinematic signatures, we analyze how they correlate with galaxy mass, environment, star formation history, and gas-phase metallicity.

REM Sleep Behavior Disorder and Narcoleptic Features in Anti–Ma2-associated Encephalitis

Science.gov (United States)

Compta, Yaroslau; Iranzo, Alex; Santamaría, Joan; Casamitjana, Roser; Graus, Francesc

2007-01-01

A 69-year-old man with anti-Ma2 paraneoplastic encephalitis presented with subacute onset of severe hypersomnia, memory loss, parkinsonism, and gaze palsy. A brain magnetic resonance imaging study showed bilateral damage in the dorsolateral midbrain, amygdala, and paramedian thalami. Videopolysomnography disclosed rapid eye movement (REM) sleep behavior disorder, and a Multiple Sleep Latency Test showed a mean sleep latency of 7 minutes and 4 sleep-onset REM periods. The level of hypocretin-1 in the cerebrospinal fluid was low (49 pg/mL). This observation illustrates that REM sleep behavior disorder and narcoleptic features are 2 REM-sleep abnormalities that (1) may share the same autoimmune-mediated origin affecting the brainstem, limbic, and diencephalic structures and (2) may occur in the setting of the paraneoplastic anti–Ma2-associated encephalitis. Citation: Compta Y; Iranzo A; Santamaría J et al. REM Sleep Behavior Disorder and Narcoleptic Features in Anti–Ma2-associated Encephalitis. SLEEP 2007;30(6):767-769. PMID:17580598

Paraneoplastic antigen Ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors.

Directory of Open Access Journals (Sweden)

Tao Cui

Full Text Available BACKGROUND: Small intestine neuroendocrine tumors (SI-NETs belong to a rare group of cancers. Most patients have developed metastatic disease at the time of diagnosis, for which there is currently no cure. The delay in diagnosis is a major issue in the clinical management of the patients and new markers are urgently needed. We have previously identified paraneoplastic antigen Ma2 (PNMA2 as a novel SI-NET tissue biomarker. Therefore, we evaluated whether Ma2 autoantibodies detection in the blood stream is useful for the clinical diagnosis and recurrence of SI-NETs. METHODOLOGY/PRINCIPAL FINDINGS: A novel indirect ELISA was set up to detect Ma2 autoantibodies in blood samples of patients with SI-NET at different stages of disease. The analysis was extended to include typical and atypical lung carcinoids (TLC and ALC, to evaluate whether Ma2 autoantibodies in the blood stream become a general biomarker for NETs. In total, 124 blood samples of SI-NET patients at different stages of disease were included in the study. The novel Ma2 autoantibody ELISA showed high sensitivity, specificity and accuracy with ROC curve analysis underlying an area between 0.734 and 0.816. Ma2 autoantibodies in the blood from SI-NET patients were verified by western blot and sequential immunoprecipitation. Serum antibodies of patients stain Ma2 in the tumor tissue and neurons. We observed that SI-NET patients expressing Ma2 autoantibody levels below the cutoff had a longer progression and recurrence-free survival compared to those with higher titer. We also detected higher levels of Ma2 autoantibodies in blood samples from TLC and ALC patients than from healthy controls, as previously shown in small cell lung carcinoma samples. CONCLUSION: Here we show that high Ma2 autoantibody titer in the blood of SI-NET patients is a sensitive and specific biomarker, superior to chromogranin A (CgA for the risk of recurrence after radical operation of these tumors.

Paraneoplastic antigen Ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors.

Science.gov (United States)

Cui, Tao; Hurtig, Monica; Elgue, Graciela; Li, Su-Chen; Veronesi, Giulia; Essaghir, Ahmed; Demoulin, Jean-Baptiste; Pelosi, Giuseppe; Alimohammadi, Mohammad; Öberg, Kjell; Giandomenico, Valeria

2010-12-30

Small intestine neuroendocrine tumors (SI-NETs) belong to a rare group of cancers. Most patients have developed metastatic disease at the time of diagnosis, for which there is currently no cure. The delay in diagnosis is a major issue in the clinical management of the patients and new markers are urgently needed. We have previously identified paraneoplastic antigen Ma2 (PNMA2) as a novel SI-NET tissue biomarker. Therefore, we evaluated whether Ma2 autoantibodies detection in the blood stream is useful for the clinical diagnosis and recurrence of SI-NETs. A novel indirect ELISA was set up to detect Ma2 autoantibodies in blood samples of patients with SI-NET at different stages of disease. The analysis was extended to include typical and atypical lung carcinoids (TLC and ALC), to evaluate whether Ma2 autoantibodies in the blood stream become a general biomarker for NETs. In total, 124 blood samples of SI-NET patients at different stages of disease were included in the study. The novel Ma2 autoantibody ELISA showed high sensitivity, specificity and accuracy with ROC curve analysis underlying an area between 0.734 and 0.816. Ma2 autoantibodies in the blood from SI-NET patients were verified by western blot and sequential immunoprecipitation. Serum antibodies of patients stain Ma2 in the tumor tissue and neurons. We observed that SI-NET patients expressing Ma2 autoantibody levels below the cutoff had a longer progression and recurrence-free survival compared to those with higher titer. We also detected higher levels of Ma2 autoantibodies in blood samples from TLC and ALC patients than from healthy controls, as previously shown in small cell lung carcinoma samples. Here we show that high Ma2 autoantibody titer in the blood of SI-NET patients is a sensitive and specific biomarker, superior to chromogranin A (CgA) for the risk of recurrence after radical operation of these tumors.

Implications of progesterone metabolism in MA-10 cells for accurate measurement of the rate of steroidogenesis

NARCIS (Netherlands)

F.F.G. Rommerts (Focko); S.R. King (Steven); P.N. Span (Paul)

2001-01-01

textabstractIn virtually all studies with MA-10 cells, progesterone RIAs have been used to measure steroid synthesis. To test whether progesterone is a stable end product, we investigated the metabolism of added tritiated progesterone and pregnenolone in MA-10 cells over a period

A novel synthetic analog of militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells

International Nuclear Information System (INIS)

Yoon, Deok Hyo; Lim, Mi-Hee; Lee, Yu Ran; Sung, Gi-Ho; Lee, Tae-Ho; Jeon, Byeong Hwa; Cho, Jae Youl; Song, Won O.; Park, Haeil; Choi, Sunga; Kim, Tae Woong

2013-01-01

A synthetic Militarin analog-1[(2R,3R,4R,5R)-1,6-bis(4-(2,4,4-trimethylpentan-2-yl)phenoxy) hexane-2,3,4,5-tetraol] is a novel derivative of constituents from Cordyceps militaris, which has been used to treat a variety of chronic diseases including inflammation, diabetes, hyperglycemia and cancers. Here, we report for the first time the synthesis of Militarin analog-1 (MA-1) and the apoptotic mechanism of MA-1 against human lung cancer cell lines. Treatment with MA-1 significantly inhibited the viability of 3 human lung cancer cell lines. The inhibition of viability and growth in MA-1-treated A549 cells with an IC 50 of 5 μM were mediated through apoptosis induction, as demonstrated by an increase in DNA fragmentation, sub-G 0 /G 1 -DNA fraction, nuclear condensation, and phosphatidylserine exposure. The apoptotic cell death caused mitochondrial membrane permeabilization through regulation of expression of the Bcl-2 family proteins, leading to cytochrome c release in a time-dependent manner. Subsequently, the final stage of apoptosis, activation of caspase-9/-3 and cleavage of poly (ADP ribose) polymerase, was induced. Furthermore, A549 lung cancer cells were more responsive to MA-1 than a bronchial epithelial cell line (BEAS-2B), involving the rapid generation of reactive oxygen species (ROS), c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) activation. The pharmacological inhibition of ROS generation and JNK/p38 MAPK exhibited attenuated DNA fragmentation in MA-1-induced apoptosis. Oral administration of MA-1 also retarded growth of A549 orthotopic xenografts. In conclusion, the present study indicates that the new synthetic derivative MA-1 triggers mitochondrial apoptosis through ROS generation and regulation of MAPKs and may be a potent therapeutic agent against human lung cancer. - Highlights: • We report a novel synthesized derivative, militarin analog-1 (MA-1). • MA-1-induced cancer cell death was triggered by the ROS

A novel synthetic analog of militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells

Energy Technology Data Exchange (ETDEWEB)

Yoon, Deok Hyo; Lim, Mi-Hee [Department of Biochemistry, Kangwon National University, Chuncheon 200-701 (Korea, Republic of); Lee, Yu Ran [Department of Physiology, School of Medicine, Chungnam National University, Daejeon 301-747 (Korea, Republic of); Sung, Gi-Ho [Mushroom Research Division, National Institute of Horticultural and Herbal Science, Rural Development Administration, Suwon 404-707 (Korea, Republic of); Lee, Tae-Ho [R and D Center, Dong-A Pharmaceutical Co, Ltd, Yongin 446-905 (Korea, Republic of); Jeon, Byeong Hwa [Department of Physiology, School of Medicine, Chungnam National University, Daejeon 301-747 (Korea, Republic of); Cho, Jae Youl [Department of Genetic Engineering, Sungkyunkwan University, Suwon 440-746 (Korea, Republic of); Song, Won O. [Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824 (United States); Park, Haeil [College of Pharmacy, Kangwon National University, Chuncheon 200-701 (Korea, Republic of); Choi, Sunga, E-mail: sachoi@cnu.ac.kr [Department of Physiology, School of Medicine, Chungnam National University, Daejeon 301-747 (Korea, Republic of); Kim, Tae Woong, E-mail: tawkim@kangwon.ac.kr [Department of Biochemistry, Kangwon National University, Chuncheon 200-701 (Korea, Republic of)

2013-12-15

A synthetic Militarin analog-1[(2R,3R,4R,5R)-1,6-bis(4-(2,4,4-trimethylpentan-2-yl)phenoxy) hexane-2,3,4,5-tetraol] is a novel derivative of constituents from Cordyceps militaris, which has been used to treat a variety of chronic diseases including inflammation, diabetes, hyperglycemia and cancers. Here, we report for the first time the synthesis of Militarin analog-1 (MA-1) and the apoptotic mechanism of MA-1 against human lung cancer cell lines. Treatment with MA-1 significantly inhibited the viability of 3 human lung cancer cell lines. The inhibition of viability and growth in MA-1-treated A549 cells with an IC{sub 50} of 5 μM were mediated through apoptosis induction, as demonstrated by an increase in DNA fragmentation, sub-G{sub 0}/G{sub 1}-DNA fraction, nuclear condensation, and phosphatidylserine exposure. The apoptotic cell death caused mitochondrial membrane permeabilization through regulation of expression of the Bcl-2 family proteins, leading to cytochrome c release in a time-dependent manner. Subsequently, the final stage of apoptosis, activation of caspase-9/-3 and cleavage of poly (ADP ribose) polymerase, was induced. Furthermore, A549 lung cancer cells were more responsive to MA-1 than a bronchial epithelial cell line (BEAS-2B), involving the rapid generation of reactive oxygen species (ROS), c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) activation. The pharmacological inhibition of ROS generation and JNK/p38 MAPK exhibited attenuated DNA fragmentation in MA-1-induced apoptosis. Oral administration of MA-1 also retarded growth of A549 orthotopic xenografts. In conclusion, the present study indicates that the new synthetic derivative MA-1 triggers mitochondrial apoptosis through ROS generation and regulation of MAPKs and may be a potent therapeutic agent against human lung cancer. - Highlights: • We report a novel synthesized derivative, militarin analog-1 (MA-1). • MA-1-induced cancer cell death was triggered by

Radiation Safety Analysis In The NFEC For Assessing Possible Implementation Of The ICRP-60 Standard

International Nuclear Information System (INIS)

Yowono, I.

1998-01-01

Radiation safety analysis of the 3 facilities in the nuclear fuel element center (NFEC) for assessing possible implementation of the ICRP-60 standard has been done. The analysis has covered the radiation dose received by workers, dose rate in the working area, surface contamination level, air contamination level and the level of radioactive gas release to the environment. The analysis has been based on BATAN regulation and ICRP-60 standard. The result of the analysis has showed that the highest radiation dose received has been found to be only around 15% of the set value in the ICRP-60 standard and only 6% of the set value in the BATAN regulation. Thus the ICRP-60 as radiation safety standard could be implemented without changing the laboratory design

Cosmic Rays Accelerated at Cosmological Shock Waves Renyi Ma1 ...

Indian Academy of Sciences (India)

Cosmic Rays Accelerated at Cosmological Shock Waves. Renyi Ma1,2,∗ ... ratio of CR to thermal energy in the ICM and WHIM based on numerical simulations and diffusive shock ... Hence, the nonthermal radiation of CRs may provide us a.

Limbic encephalitis and antibodies to Ma2: a paraneoplastic presentation of breast cancer.

Science.gov (United States)

Sutton, I; Winer, J; Rowlands, D; Dalmau, J

2000-08-01