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Sample records for akashi kaikyo ohashi

  1. Construction of stiffening girder for Akashi straits bridge. Installation with use of latest bridging technology; Akashi kaikyo ohashi hoko keta kasetsu koji. Saishin kakyo gijutsu wo kushishite kasetsu

    Energy Technology Data Exchange (ETDEWEB)

    Oe, S. [Honshu-Shikoku Bridge Authority, Tokyo (Japan)

    1996-05-25

    The Akashi straits bridge is the Kobe-Naruto route of the bridge connecting Honshu and Shikoku; the bridge links Kobe in Hyogo prefecture with Awaji Island and, when completed, it will be a 3-span 2-hinge suspension bridge with the longest center effective span in the world. This report centers on the outline of the construction of stiffening girders for the Akashi straits bridge and especially on the characteristics of the engineering method newly employed. As the method of installing the stiffening girders, an overhang installation of face bars was employed which was a time-tested method. As the installing direction of the side spans, it was decided to install them from the anchorage to the tower. At the beginning, six large block installations were performed. A special balance was developed for the installation of short hanger parts for the purpose of enhancing safety and reduction in the process. A rubber-tired transporting truck was adopted for transporting members of framework on the bridge. GPS survey was used as a method for surveying the configuration. The subject engineering method was based on the construction of suspension bridge stiffening trusses in the past Honshu-Shikoku connecting bridge and reinforced with the improvements as above. Since the bridge is in the middle of construction, a subsequent report will hopefully be made on the actual results of the installation and the spanning after the closure. 8 figs., 2 tabs.

  2. The Akashi Kaikyo Bridge and the Storebælt Bridge

    DEFF Research Database (Denmark)

    Gimsing, Niels Jørgen

    1999-01-01

    With the completion of the Akashi Kaikyo Bridge and the Storebælt East Bridge the development of the suspension bridge technology in the 20th century has manifested itself in two impressive structures. With the present echnology may bridges of similar (and also more modest) dimensions...... will undoubtedly be built far into the next century. For bridges going beyond the spans of existing bridges it is, however, likely that new concepts will be developed....

  3. Newly developed high performance structural steels for long span bridge construction; Chotaikyo ni shiyosareru shinkozai

    Energy Technology Data Exchange (ETDEWEB)

    Tomita, Y. [Nippon Steel Corp., Tokyo (Japan)

    1998-11-15

    This paper reports new steels for long span bridge construction with the thick steel plate as a main part. On the basis of the high-tension steel utilizing technology examined around 1965, a reheated, quenched-and-tempered martensitic steel plate (HT690) was used for the Onaruto Bridge and Seto Ohashi Bridge in a Honsyu-Shikoku linking project. Moreover, a larger number of quenched martensitic high-tension steel plates (HT670 and HT780) were used for the Yojima Bridge together with existing SM400, SM490, SM520, and SM570 steel plates. The lately built Akashi Kaikyo Ohashi Bridge that is 1990 m between struts is longest in the world. The newly developed steel plate (HT780) for a bridge girder of which weldability was improved for lightening was used actually. To reduce the welding cost or improve the welding environment, this steel plate decreased the preheating temperature for weld cracking prevention in a heat-affected zone from about 100degC to 50degC or less. A new wire (of 1800Mpa in tensile strength) was also used for a cable. In future, the bridge girder will be economically and rationally manufactured by the development of design and construction methods that fully draw the characteristics of the new steel. 33 refs., 9 figs., 2 tabs.

  4. Genetic diversity analysis in blackgram (Vigna mungo (L.) Hepper) using AFLP and transferable microsatellite markers from azuki bean (Vigna angularis (Willd.) Ohwi & Ohashi).

    Science.gov (United States)

    Gupta, S K; Gopalakrishna, T

    2009-02-01

    Genetic diversity in 20 elite blackgram (Vigna mungo (L.) Hepper) genotypes was studied using microsatellite and AFLP markers. Thirty-six microsatellite markers from azuki bean (Vigna angularis (Willd.) Ohwi & Ohashi) were successfully amplified across the 20 blackgram genotypes and 33 microsatellite markers showed polymorphism. A total of 137 microsatellite alleles were generated with an average of 4.1 alleles per locus. The number of alleles ranged from two to nine and the polymorphic information content value for the microsatellite markers varied from 0.10 to 0.87 with an average of 0.49. Microsatellite markers were highly informative and a combination of only three microsatellite markers (CEDG264, CEDG173, and CEDG044) was sufficient to discriminate all 20 blackgram genotypes. In the case of AFLP, 11 primer pairs generated 324 polymorphic marker fragments. The polymorphic information content values for AFLP primer combinations ranged from 0.21 to 0.34 with an average of 0.29. Similarity measures and clustering analyses were made using microsatellite and AFLP data separately. The resulting dendrograms distributed the 20 blackgram genotypes into five main clusters. The dendrograms were comparable with each other with the Mantel test between the cophenetic matrices of microsatellite data and AFLP data showing moderate correlation (r = 0.64). The results of the principal components analysis were well congruent with the dendrograms. In the dendrograms as well as in the principal components analyses, genotype Trombay wild (Vigna mungo var. silvestris) was placed separately from rest of the genotypes. This study demonstrated that the azuki bean microsatellite markers are highly polymorphic and informative and can be successfully used for genome analysis in blackgram. Results indicate that sufficient variability is present in the blackgram genotypes and would be helpful in the selection of suitable parents for breeding purposes and gene mapping studies.

  5. Aseismic structure of the foundations of super long span bridges; Cho chodai kyoryo no kiso ni motomerareru taishin kozo

    Energy Technology Data Exchange (ETDEWEB)

    Yamagata, M. [Honshu Shikoku Bridge Authority, Kobe (Japan); Tanaka, T. [Oriental Consultants Co. Ltd., Tokyo (Japan)

    1995-09-20

    All the long span bridges that are planned across the straits on the second national expressway, are essential foundations on the deep sea bottom or on the bedrock overlaid with deep sediments, moreover have longer spans than the Akashi Kaikyo Bridge, furthermore are under severe condition that superstructure reaction force is increased with the enlarged spans. Consequently, aseismic stability greatly influences the specifications of the foundations. Although, in a long span bridge foundation like this, it is possible to design and execute on subsequent of same type with Akashi Kaikyo Bridge which is going to execute now, it is evident that the cost of construction increases widely per unit length. In this paper, the concept of an aseismic structure for the foundations of super long span bridges based on the principle of earthquake countermeasures is described. In particular, authors have devised a new type of foundation for the deep sea, named as a `platform`, with a weight about half that of conventional one. The feasibility of this new foundation rests on the surveying, designing and construction technologies acquired from the Akashi Kaikyo Bridge project and on research and development extending over several years. 25 refs., 9 figs., 5 tabs.

  6. Traffic supervisory/control system for Kobe-Awaji- Naruto expressway of Honshu-Shikoku Bridge Authority; Honshu Shikoku Renrakukyo Kodan nonyu no Kobe Awaji Naruto jidoshado kotsu kansei shisetsu seigyo system

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Toshiba delivered the traffic supervisory/control system for Kobe-Awaji-Naruto expressway of Honshu-Shikoku Bridge Authority opened in May 1998. This traffic supervisory system rapidly exactly collects and services the information on the expressway of 89km including Akashi Kaikyo bridge and O-Naruto bridge. The facility control system totally efficiently maintains and controls various facilities for lighting and air circulation of tunnels on the expressway. The previous control system transmitted road information on traffic volume and traffic congestion to offices by using specific lines and terminals, while this system with a monitoring function using intranet can easily service such information by existing PCs. (translated by NEDO)

  7. Traffic supervisory/control system for Kobe-Awaji- Naruto expressway of Honshu-Shikoku Bridge Authority. Honshu Shikoku Renrakukyo Kodan nonyu no Kobe Awaji Naruto jidoshado kotsu kansei shisetsu seigyo system

    Energy Technology Data Exchange (ETDEWEB)

    1999-03-01

    Toshiba delivered the traffic supervisory/control system for Kobe-Awaji-Naruto expressway of Honshu-Shikoku Bridge Authority opened in May 1998. This traffic supervisory system rapidly exactly collects and services the information on the expressway of 89km including Akashi Kaikyo bridge and O-Naruto bridge. The facility control system totally efficiently maintains and controls various facilities for lighting and air circulation of tunnels on the expressway. The previous control system transmitted road information on traffic volume and traffic congestion to offices by using specific lines and terminals, while this system with a monitoring function using intranet can easily service such information by existing PCs. (translated by NEDO)

  8. Horizontal gust response of `Tatara Bridge` under construction; `Tatara ohashi` kasetsuji no taifu anteisei

    Energy Technology Data Exchange (ETDEWEB)

    Matsuda, K.; Iwasaki, T.; Tokushige, M.; Toriumi, R. [Ishikawajima-Harima Heavy Industries Co. Ltd., Tokyo (Japan)

    1999-03-01

    Wind tunnel tests of a long-span cable-stayed bridge under construction were conducted with two types of turbulent boundary layer simulations. The level of agreement between the wind tunnel measurements and a wind buffeting analysis varied with the type of turbulent boundary layer. An investigation of this behavior found that the aerodynamic admittance used in the buffeting analysis was different from the measured aerodynamic admittance. Past research showed that buffeting analysis based on strip theory, which assumes a spanwise correlation between the fluctuating wind velocity and the fluctuating aerodynamic loads, does not always hold. (author)

  9. Coating of long span bridges; Chotaikyo no toso

    Energy Technology Data Exchange (ETDEWEB)

    Kawanishi, H. [Nippon Paint Co. Ltd., Osaka (Japan)

    1998-11-15

    A composite anti-corrosion coating method (zinc rich primer + epoxy resin primer + polyurethane resin primer) was used for the Seto Ohashi Bridge. The anti-corrosion coating system in the Akashi Ohashi Bridge is the same as described above. This paper mainly describes the coating in a Honshu-Shikoku linking bridge. In the coating system, product blasting is used as rough coating. In the whole process, coating is basically performed at the factory. The anti-corrosion against a friction junction plane and splice plate is also carried out. For example, a rustproof bolt is used in the easy-to-corrode part. Coating is performed to obtain a thick film of more than 200 {mu}m. The edge of a member is rounded. The zinc dust in a zinc rich primer performs sacrifice anti-corrosion. The outside-air isolation film uses an epoxy resin primer that is excellent in water resistance and chemical resistance. This film improves the anti-corrosion effect by isolating the moisture or corrosive substance that permeates through the coated film from the outside air. If the weather resistance of the fluoroethylene resin primer used instead of a polyurethane resin primer has final coating quality as expected, the maintenance cycle in an offshore bridge can be more extended than the current cycle of about 10 to 15 years. 1 ref., 1 fig., 5 tabs.

  10. Development of a black gram [Vigna mungo (L.) Hepper] linkage map and its comparison with an azuki bean [Vigna angularis (Willd.) Ohwi and Ohashi] linkage map.

    Science.gov (United States)

    Chaitieng, B; Kaga, A; Tomooka, N; Isemura, T; Kuroda, Y; Vaughan, D A

    2006-11-01

    The Asian Vigna group of grain legumes consists of six domesticated species, among them black gram is widely grown in South Asia and to a lesser extent in Southeast Asia. We report the first genetic linkage map of black gram [Vigna mungo (L.) Hepper], constructed using a BC(1)F(1) population consisting of 180 individuals. The BC(1)F(1) population was analyzed in 61 SSR primer pairs, 56 RFLP probes, 27 AFLP loci and 1 morphological marker. About 148 marker loci could be assigned to the 11 linkage groups, which correspond to the haploid chromosome number of black gram. The linkage groups cover a total of 783 cM of the black gram genome. The number of markers per linkage group ranges from 6 to 23. The average distance between adjacent markers varied from 3.5 to 9.3 cM. The results of comparative genome mapping between black gram and azuki bean show that the linkage order of markers is highly conserved. However, inversions, insertions, deletions/duplications and a translocation were detected between the black gram and azuki bean linkage maps. The marker order on parts of linkage groups 1, 2 and 5 is reversed between the two species. One region on black gram linkage group 10 appears to correspond to part of azuki bean linkage group 1. The present study suggests that the azuki bean SSR markers can be widely used for Asian Vigna species and the black gram genetic linkage map will assist in improvement of this crop.

  11. Horizontal gust response of 'Tatara Bridge' under construction. 'Tatara ohashi' kasetsuji no taifu anteisei

    Energy Technology Data Exchange (ETDEWEB)

    Matsuda, K.; Iwasaki, T.; Tokushige, M.; Toriumi, R. (Ishikawajima-Harima Heavy Industries Co. Ltd., Tokyo (Japan))

    1999-03-01

    Wind tunnel tests of a long-span cable-stayed bridge under construction were conducted with two types of turbulent boundary layer simulations. The level of agreement between the wind tunnel measurements and a wind buffeting analysis varied with the type of turbulent boundary layer. An investigation of this behavior found that the aerodynamic admittance used in the buffeting analysis was different from the measured aerodynamic admittance. Past research showed that buffeting analysis based on strip theory, which assumes a spanwise correlation between the fluctuating wind velocity and the fluctuating aerodynamic loads, does not always hold. (author)

  12. Genetics Home Reference: Kabuki syndrome

    Science.gov (United States)

    ... Central Miyake N, Koshimizu E, Okamoto N, Mizuno S, Ogata T, Nagai T, Kosho T, Ohashi H, Kato ... N, Mizuno S, Okamoto N, Ohashi H, Shiina M, Ogata K, Tsurusaki Y, Nakashima M, Saitsu H, Niikawa ...

  13. A comparative study on aluminum induced oxalate secretion in Polygonum aviculare L and citrate secretion in Vigna umbellata [Thunb] Ohwi & Ohashi%铝胁迫下萹蓄与饭豆根系有机酸分泌特性比较

    Institute of Scientific and Technical Information of China (English)

    尤江峰; 张蕾; 杨建立; 郑绍建

    2007-01-01

    以萹蓄和饭豆为试验材料,从对Al胁迫的响应时间、蛋白质合成抑制剂的影响、体内有机酸含量变化及阴离子通道抑制剂的影响等方面,比较研究了Al诱导根系分泌有机酸的差异,以进一步明确铝(Al)诱导植物根系有机酸分泌的过程.结果表明,萹蓄根系在Al胁迫后30 min内分泌出草酸,而Al胁迫至少4 h后饭豆根系才开始分泌柠檬酸;蛋白质合成抑制剂环己亚酰胺(Cycloheximide,CHM)不影响萹蓄根系草酸的分泌,但抑制了84% Al诱导的饭豆根系柠檬酸的分泌,表明前者不需要新蛋白质的诱导合成,却是后者所必需的.Al处理不改变萹蓄根尖草酸的含量,但明显提高了饭豆根尖柠檬酸的含量;阴离子通道抑制剂苯甲酰甲醛(Phenylglyoxal,PG)和蒽-9-羧酸(Anthrancene-9-carboxylic acid,A-9-C)分别有效抑制Al诱导萹蓄根系草酸的分泌及饭豆根系柠檬酸的分泌,再次证明两者有机酸的分泌是通过某种被Al所诱导或激活的阴离子通道所实现的.

  14. China Moves Out: Stepping Stones Toward a New Maritime Strategy

    Science.gov (United States)

    2015-04-01

    global in scope, which will influence how the country will employ its navy. Piracy is a threat to China’s economic interests and is subsumed under...objectives of enhancing capabilities to protect SLOCs and strate- gic chokepoints, countering piracy threats, and protecting commercial interests...Strait,” Yomiuri Shimbun; “PLA Sorties Threaten Encirclement,” Taipei Times Online , February 9, 2012; “Chinese Navy Fleet Passes Through Osumi-kaikyo

  15. Reference: HDZIPIIIAT [PLACE

    Lifescience Database Archive (English)

    Full Text Available HDZIPIIIAT Ohashi-Ito K, Kubo M, Demura T, Fukuda H. Class III Homeodomain Leucine-...Zipper Proteins Regulate Xylem Cell Differentiation. Plant Cell Physiol. 46: 1646-1656 (2005) PubMed: 16081527 ...

  16. A new synonym of Hylodesmum podocarpum ssp.podocarpum (Leguminosae)%圆菱叶长柄山蚂蝗一新异名

    Institute of Scientific and Technical Information of China (English)

    高信芬

    2004-01-01

    Close examination of the type material of Podocarpium lancangense Y. Y. Qian has shown that this species is indistinguishable from Hylodesmum podocarpum (DC.) H. Ohashi & R. R. Mill ssp. Podocarpum, and thus is reduced to synonymy herein.%查阅了澜沧长柄山蚂蝗Hylodesmum lancangense (Y. Y. Qian) X. Y. Zhu & H. Ohashi的模式标本后,确认该种应归并入圆菱叶长柄山蚂蝗H. podocarpum (DC.) H. Ohashi & R. R. Mill ssp. podocarpum.

  17. 中国豆科植物一新记录种--多皱假木豆%Dendrolobium rugosum (Prain) Schindler (Leguminosae), a new record to China

    Institute of Scientific and Technical Information of China (English)

    朱相云; 大桥广好

    2001-01-01

    @@ Ohashi (1995) published a paper showing that Dendrolobium rugosum (Prain) Schindler was new to China. Unfortunately this name did not appear in Flora Reipublicae Popularis Sinicae Vol 41. (Yang & Huang, 1995). This paper describes this species in detail and gives its geographical distribution.

  18. Additions to the Flora of Hainan, China (Ⅱ)%海南植物新资料(Ⅱ)

    Institute of Scientific and Technical Information of China (English)

    郑希龙; 王军; 陈沂章; 李榕涛; 魏建和; 马子龙; 朱平

    2014-01-01

    报道了3种海南新记录植物,分别为密毛长柄山蚂蝗[Hylodesmum densum(C.Chen&X.J.Cui)H.Ohashi &R.R.Mill]、通城虎(Aristolochia fordiana Hemsl.)及石生鸡脚参[Orthosiphon marmoritis (Hance) Dunn].

  19. Heuristic Procedures for 0-1 Integer Programming.

    Science.gov (United States)

    1987-03-01

    A 30 60 0.021 0 ST B 30 60 0.010 0 ie 40 Chapter 4 Conclusions A heuristic algorithm aims at obtaining a very good feasible solution relatively...Department of Operations Research, Stanford University, February, 1977. 19. Ibaraki, T., Ohashi, T., and Mine, H. " A Heuristic Algorithm for Mixed

  20. Reference: E2F1OSPCNA [PLACE

    Lifescience Database Archive (English)

    Full Text Available E2F1OSPCNA Kosugi S, Ohashi Y E2F sites that can interact with E2F proteins cloned from rice are require...d for meristematic tissue-specific expression of rice and tobacco proliferating cell nuclear antigen promoters Plant J 29: 45-59 (2002) PubMed: 12060226; ...

  1. Reference: SITEIIAOSPCNA [PLACE

    Lifescience Database Archive (English)

    Full Text Available SITEIIAOSPCNA Kosugi S, Suzuka I, Ohashi Y Two of three promoter elements identifie...d in a rice gene for proliferating cell nuclear antigen are essential for meristematic tissue-specific expression Plant J 7:877-886 (1995) PubMed: 7599648; ...

  2. A new species of Dalbergia (Leguminosae from Malay Peninsula

    Directory of Open Access Journals (Sweden)

    Bambang - Sunarno

    2003-12-01

    Full Text Available SUNARNO, BAMBANG & OHASHI, HIROSHI. 2002. A new species of Dalbergia (Leguminosae from Malay Peninsula. Reinwardtia 12(1: 117–119. ⎯ A new species, Dalbergia johoriensis from the Malay Peninsula is described. It is close to D. rostrata and D. havilandii but readily distinguished by the grooved midrib beneath, flowers with narrower standard and wings and style hairy in the lower part.

  3. A Framework for the Measurement of Simulated Behavior Performance

    Science.gov (United States)

    2011-03-24

    takes professional soccer team recordings to aid Robocup team tactics development, measuring success through goal tracking [5]. With interest in...Cloning for Simulator Validation”. Ubbo Visser, Fernando Ribeiro, Takeshi Ohashi, and Frank Dellaert (editors), RoboCup 2007: Robot Soccer World Cup...XI, volume 5001 of Lecture Notes in Computer Science, 329–336. Springer Berlin / Heidelberg, 2008. URL http://dx.doi.org/10. 1007/978-3-540-68847-1_32

  4. 地域福祉とソーシャルワーク : コミュニティワークvs. コミュニティ・ソーシャルワーク

    OpenAIRE

    2004-01-01

    Community Social Work or Community Work? Which terminology is the more suitable in the area of social work practice under Community Welfare? I believe that question is very timely and relevant today. Kensaku Ohashi, the president of the Japan Community Welfare Society has emphasized, that, "community social work is the contemporary method in community-based social work". However, the Council of Social Welfare believes somewhat differently. "Community work is the only method of community welfa...

  5. Characterization of bottom sediments from Osaka Bay, Japan

    Science.gov (United States)

    Tokunaga, S.; Hoshika, A.; Tatsumoto, H.

    1995-06-01

    The physical, chemical, and dewatering characteristics of 19 bottom sediments from Osaka Bay, Japan, have been analyzed to aid in the development of sediments in the coastal bay area. The sediments in the east near Osaka Port were highly polluted from the influence of human activities and were difficult to dewater. These sediments were composed of fine particles, low in pH, zetapotential, and initial settling rate, and were high in ignition loss, metal concentrations, compression volume, specific resistance, cake water content, and drying index. However, the sediments near Akashi Channel showed the reverse where they are affected by strong tidal current. A correlation analysis has been made of all the parameters. There are significant relationships between all the dewatering parameters. Therefore, sediments difficult to dewater by gravity settling are also difficult to dewater by vacuum filtration and solar evaporation. Sediments containing fine particles and pollutants are difficult to dewater. Several forms of pollutants can occur in the sediments.

  6. Role of Activin A in Immune Response to Breast Cancer

    Science.gov (United States)

    2014-12-01

    reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org...carcinogenesis. Br Med Bull (1964) 20:154–8. 6. Staveley-O’Carroll K, Sotomayor E, Montgomery J, Borrello I, Hwang L, Fein S, et al. Induction of antigen...production of interleukin-12. Biol Pharm Bull (2003) 26:1336–41. doi:10.1248/bpb.26.1336 124. Sugiyama T, Fujiwara K, Ohashi Y, Yokota H, Hatae M

  7. Discovery of Infalling Motion with Rotation of the Cluster-forming Clump S235AB and Its Implication to the Clump Structures

    Science.gov (United States)

    Shimoikura, Tomomi; Dobashi, Kazuhito; Matsumoto, Tomoaki; Nakamura, Fumitaka

    2016-12-01

    We report the discovery of infalling motion with the rotation of S235AB, a massive cluster-forming clump (˜ 1× {10}3 {M}⊙ ) in the S235 region. Our C18O observations with the 45 m telescope at the Nobeyama Radio Observatory have revealed an elliptical shape of the clump. A position-velocity diagram taken along its major axis exhibits two well-defined peaks symmetrically located, with respect to the clump center. This is similar to that found for a dynamically infalling envelope with rotation around a single protostar, modeled by N. Ohashi et al., indicating that the cluster-forming clump is also collapsing by the self-gravity toward the clump center. With analogue to Ohashi et al.'s model, we made a simple model of an infalling, rotating clump to fit the observed data. Based on the inferred model parameters, as well as results of earlier observations and simulations in the literature, we discuss the structures of the clump such as the relation among the global mass infall rate (˜ 1× {10}-3 {M}⊙ yr-1), formation of a compact core (with a mass and size of ˜4 {M}⊙ and ≲ 0.1 pc) at the center, and a massive star (˜11 {M}⊙ ) forming in the core.

  8. Discovery of Infalling Motion with Rotation of the Cluster-Forming Clump S235AB and Its Implication to the Clump Structures

    CERN Document Server

    Shimoikura, Tomomi; Matsumoto, Tomoaki; Nakamura, Fumitaka

    2016-01-01

    We report the discovery of infalling motion with rotation of S235AB the massive cluster-forming clump (~10^3 Mo) in the S235 region. Our C18O observations with the 45m telescope at the Nobeyama Radio Observatory have revealed the elliptical shape of the clump. Position-velocity (PV) diagram taken along its major axis exhibits two well-defined peaks symmetrically located with respect to the clump center, which is similar to that found for a dynamically infalling envelope with rotation around a single protostar modeled by N. Ohashi and his collaborators, indicating that the cluster-forming clump is also collapsing by the self-gravity toward the clump center. With analogue to Ohashi's model, we made a simple model of an infalling, rotating clump to fit the observed data. Based on the inferred model parameters as well as results of earlier observations and simulations in the literature, we discuss structures of the clump such as the relation among the global mass infall rate (~10^-3 Mo/yr), formation of a compact...

  9. Comparative study on seed sprouting characteristics and drought tolerance of mung bean、cowpea、red bean%绿豆、豇豆、小豆种子萌发特性及耐旱性比较研究

    Institute of Scientific and Technical Information of China (English)

    王云; 师桂花; 张云华; 王芳; 乔宏伟; 白永贵; 王立岩

    2004-01-01

    绿豆(Vigna radiata(L.)Wilczek)、豇豆(Vigna unguiculata L.)、小豆(Vigna angularis(willd)Ohwi&Ohashi)是我国北方旱作区主栽的粮、菜兼用作物,在适宜的环境条件下萌发生长良好,但由于北方春季普遍干旱,严重影响了三种豆类的生产。本文研究了模拟干旱条件下三种豆类种子吸水萌发特性和耐回干能力,以期为生产提供理论依据。

  10. Action of xyloglucan hydrolase within the native cell wall architecture and its effect on cell wall extensibility in azuki bean epicotyls.

    Science.gov (United States)

    Kaku, Tomomi; Tabuchi, Akira; Wakabayashi, Kazuyuki; Kamisaka, Seiichiro; Hoson, Takayuki

    2002-01-01

    Xyloglucan hydrolase (XGH) has recently been purified from the cell wall of azuki bean (Vigna angularis Ohwi et Ohashi) epicotyls as a new type of xyloglucan-degrading enzyme [Tabuchi et al. (2001) Plant Cell Physiol. 42: 154]. In the present study, the effects of XGH on the mechanical properties of the cell wall and on the level and the molecular size of xyloglucans within the native wall architecture were examined in azuki bean epicotyls. When the epidermal tissue strips from the growing regions of azuki bean epicotyls were incubated with XGH, the mechanical extensibility of the cell wall dramatically increased. XGH exogenously applied to cell wall materials (homogenates) or epidermal tissue strips decreased the amount of xyloglucans via the solubilization of the polysaccharides. Also, XGH substantially decreased the molecular mass of xyloglucans in both materials. These results indicate that XGH is capable of hydrolyzing xyloglucans within the native cell wall architecture and thereby increasing the cell wall extensibility in azuki bean epicotyls.

  11. Mechanoreceptors rather than sedimentable amyloplasts perceive the gravity signal in hypergravity-induced inhibition of root growth in azuki bean.

    Science.gov (United States)

    Soga, Kouichi; Wakabayashi, Kazuyuki; Kamisaka, Seiichiro; Hoson, Takayuki

    2005-01-01

    Elongation of primary roots of azuki bean (Vigna angularis Ohwi et Ohashi) was suppressed under hypergravity conditions produced by centrifugation, such that the growth rate decreased in proportion to the logarithm of the magnitude of the gravity. The removal of the root cap did not influence the hypergravity-induced inhibition of root growth, although it completely inhibited the gravitropic root curvature. Lanthanum and gadolinium, blockers of mechanoreceptors, nullified the growth-inhibitory effect of hypergravity. These results suggest that the gravity signal for the hypergravity-induced inhibition of root growth is perceived independently from that of gravitropism, which involves amyloplasts as statoliths. Horizontal and basipetal hypergravity suppressed root growth as did acropetal hypergravity, all of which were nullified by the presence of lanthanum or gadolinium. These findings suggest that mechanoreceptors on the plasma membrane perceive the gravity signal independently of the direction of the stimuli and roots may utilise it to regulate their growth rate.

  12. Hypergravity increases the molecular mass of xyloglucans by decreasing xyloglucan-degrading activity in azuki bean epicotyls.

    Science.gov (United States)

    Soga, K; Wakabayashi, K; Hoson, T; Kamisaka, S

    1999-06-01

    Elongation growth of dark-grown azuki bean (Vigna angularis Ohwi et Ohashi cv. Takara) epicotyls was suppressed by hypergravity at 30 x g and above. Acceleration at 300 x g significantly decreased the mechanical extensibility of cell walls. The amounts of cell wall polysaccharides (pectin, hemicellulose-II and cellulose) per unit length of epicotyls increased under the hypergravity condition. Hypergravity also increased the amounts and the weight-average molecular mass of xyloglucans in the hemicellulose-II fraction, while decreasing the activity of xyloglucan-degrading enzymes extracted from epicotyl cell walls. These results suggest that hypergravity increases the amounts and the molecular mass of xyloglucans by decreasing xyloglucan-degrading activity. Modification of xyloglucan metabolism as well as the thickening of cell walls under hypergravity conditions seems to be involved in making the cell wall mechanically rigid, thereby inhibiting elongation growth of azuki bean epicotyls.

  13. Transient increase in the levels of gamma-tubulin complex in reorientation of cortical microtubules by gravity in azuki bean epicotyls

    Science.gov (United States)

    Soga, Kouichi; Kotake, Toshihisa; Wakabayashi, Kazuyuki; Kamisaka, Seiichiro; Hoson, Takayuki

    Azuki bean (Vigna angularis Ohwi et Ohashi) seedlings were exposed to centrifugal hypergravity, and the changes in the orientation of cortical microtubules and the expression of genes cording γ-tubulin complex (VaTUBG and VaSpc98p) were examined. By 300 g treatment, the percentage of cells with transverse microtubules was decreased, while that with longitudinal microtubules was increased in epicotyls. Hypergravity increased the expression of VaTUBG and VaSpc98p transiently. Also, the expression of both genes was increased transiently by removal of hypergravity stimulus. Lanthanum and gadolinium ions, potential blockers of mechanosensitive calcium ion-permeable channels (mechanoreceptors), nullified reorientation of microtubules as well as up-regulation of expression of VaTUBG and VaSpc98p by hypergravity. These results suggest that mechanoreceptors on the plasma membrane may perceive the gravity signal, which leads to reorientation of cortical microtubules by transiently stimulating the formation of γ-tubulin complex.

  14. Efficiency of pulse-mode dielectric barrier discharge excimer lamp in constant duty cycle

    Science.gov (United States)

    Akashi, Haruaki; Oda, Akinori; Sakai, Yosuke

    2008-10-01

    Efficiency of pulse-mode dielectric barrier discharge (DBD) excimer lamp under constant duty cycle with increasing applied voltage has been simulated using two dimensional fluid model[1]. Xe gas with 300Torr pressure is assumed. And the simulated region considered in this model is 1cm(gap length)x3cm(radial length). Periodical boundary conditions are assumed for the radial direction boundaries. The both electrodes are covered with dielectrics and their thickness is 0.2cm. 5˜8kV trapezoid shape voltage is applied with the same voltage rising ratio and 50% duty ratio waveform with 200x10^3pps repetition rate. The discharge occurs at the rising edge and tailing edge of applied voltage. 172nm VUV intensity obtained from first discharge is higher than second one in lower applied voltage (<6kV) case. And in higher voltage case, the intensity from second discharge becomes higher. This is explained by shortening of interval time between the discharges. The short interval time makes higher initial electron density for second discharge. As a results, the input and 172nm VUV output power increases with increasing applied voltage, but the efficiency decreases. Because of inefficient surface discharge [1]H. Akashi et al, IEEE Trans. Plasma Science, Vol.33,No.2(2005,4)pp.308-309

  15. Modeling of dielectric barrier discharge excimer lamp excited by mono polar voltage pulses

    Science.gov (United States)

    Akashi, Haruaki; Oda, Akinori; Sakai, Yosuke

    2007-10-01

    Filametal discharges in Dielectric Barrier Discharge (DBD) excimer lamp excited by mono polar voltage pulses has been simulated using two dimensional fluid model. And the differences of the filament discharges formations between mono polar case and bipolar case [1] have been examined. Xe gas was used and its pressure is 300Torr. Simulated region is 1cm (gap length) x 3cm (radial length). Periodical boundary conditions are assumed for the radial direction boundaries. The both electrodes are covered with dielectrics and their thickness is 0.2cm. Applied voltage is 5kV trapezoid shape with 50% duty ratio waveform and its repetition rate is 200kpps. First a small amount of electron-ion pair is provided in the middle of the gap for initial condition. Then the voltage starts to apply. In the case of bipolar excitation, the discharge starts from one filament (streamer discharge), and finally, 5 filaments are obtained self-consistently. In the case of mono polar case, as first, similar to bipolar case, the discharge starts from one filament, however, only 3 filaments have been obtained. This result is similar to that of 100kHz bipolar voltage case. [1] H. Akashi et al, IEEE Trans. Plasma Science, Vol.33, No.2 (2005) pp.308-309

  16. Visualization of strong around motion calculated from the numerical simulation of Hyogo-ken Nanbu earthquake; Suchi simulation de miru Hyogoken nanbu jishin no kyoshindo

    Energy Technology Data Exchange (ETDEWEB)

    Furumura, T. [Hokkaido Univ. of Education, Sapporo (Japan); Koketsu, K. [The University of Tokyo, Tokyo (Japan). Earthquake Research Institute

    1996-10-01

    Hyogo-ken Nanbu earthquake with a focus in the Akashi straits has given huge earthquake damages in and around Awaji Island and Kobe City in 1995. It is clear that the basement structure, which is steeply deepened at Kobe City from Rokko Mountains towards the coast, and the focus under this related closely to the local generation of strong ground motion. Generation process of the strong ground motion was discussed using 2D and 3D numerical simulation methods. The 3D pseudospectral method was used for the calculation. Space of 51.2km{times}25.6km{times}25.6km was selected for the calculation. This space was discretized with the lattice interval of 200m. Consequently, it was found that the basement structure with a steeply deepened basement, soft and weak geological structure thickly deposited on the basement, and earthquake faults running under the boundary of base rock and sediments related greatly to the generation of strong ground motion. Numerical simulation can be expected to predict the strong ground motion by shallow earthquakes. 9 refs., 7 figs.

  17. Investigation of phenomena of Southern Hyogo Earthquake, and observation of thunderbolts in winter using the integrated thunderbolt observation system; Hyogoken nanbu jishin no gensho no kaimei, sogo kaminari kansoku system ni yoru toki kaminari kansoku

    Energy Technology Data Exchange (ETDEWEB)

    Kurihara, C.; Shindo, T. [Central Research Institute of Electric Power Industry, Tokyo (Japan)

    1996-08-01

    The focal region of this earthquake was in the upper part of crusher zone of granite, and the maximum horizontal acceleration was about 300 gal which was increased at the surface into two times. Energy input would be concentrated between the first and second waves, to act on the structures resulting in the immediate destruction. The non-linear analysis method based on the effective stress was applied. As a result, the damping of horizontal acceleration and enhancing of vertical acceleration accompanied with liquefaction, and the amount of ground subsidence at the foundation of main tower of Akashi Bridge on the sand/gravel ground could be well simulated. The position of the fault and deformation structure in the surface layer could be detected down to the depth of more than 10 m by means of high density electrical exploration and underground radar exploration. (2) To observe thunderbolt field at various points and collect these data effectively, a remote control thunderbolt observation system was constructed. Thunderbolts in winter at Fukui were observed by integrating this system with the conventional optical observation, observation of thunder current, and observation of thunder cloud using Doppler radar. About a half of thunderstrokes in winter were due to the straight polarity discharge. It was also confirmed that generation of upward thunderbolts relates closely to the electrical activities in the thunder cloud. 6 figs.

  18. Codon Usage Bias and Determining Forces in Green Plant Mitochondrial Genomes

    Institute of Scientific and Technical Information of China (English)

    Bin Wang; Jing Yuan; Jing Liu; Liang Jin; Jian-Qun Chen

    2011-01-01

    The phenomenon of codon usage bias has been observed in a wide range of organisms. As organisms evolve, how their codon usage pattern change is still an intriguing question. In this article, we focused on the green plant mitochondrial genomes to analyze the codon usage patterns in different lineages,and more importantly, to investigate the possible change of determining forces during the plant evolution. Two patterns were observed between the separate lineages of green plants: Chlorophyta and Streptophyta. In Chlorophyta lineages, their codon usages showed substantial variation (from strongly A, T-biased to strongly G, C-biased); while in Streptophyta lineages, especially in the land plants, the overall codon usages are interestingly stable. Further, based on the Nc-GC3s plots and Akashi's scaled XZ-tests, we found that lineages within Chlorophyta exhibit much stronger evidence of deviating from neutrality; while lineages within Streptophyta rarely do so. Such differences, together with previous reports based on the chloroplast data, suggests that after plants colonized the land, their codon usages in organellar genomes are more reluctant to be shaped by selection force.

  19. An SSR-based linkage map of yardlong bean (Vigna unguiculata (L.) Walp. subsp. unguiculata Sesquipedalis Group) and QTL analysis of pod length.

    Science.gov (United States)

    Kongjaimun, Alisa; Kaga, Akito; Tomooka, Norihiko; Somta, Prakit; Shimizu, Takehiko; Shu, Yujian; Isemura, Takehisa; Vaughan, Duncan A; Srinives, Peerasak

    2012-02-01

    Yardlong bean (Vigna unguiculata (L.) Walp. subsp. unguiculata Sesquipedalis Group) (2n = 2x = 22) is one of the most important vegetable legumes of Asia. The objectives of this study were to develop a genetic linkage map of yardlong bean using SSR makers from related Vigna species and to identify QTLs for pod length. The map was constructed from 226 simple sequence repeat (SSR) markers from cowpea (Vigna unguiculata (L.) Walp. subsp. unguiculata Unguiculata Group), azuki bean (Vigna angularis (Willd.) Ohwi & Ohashi), and mungbean (Vigna radiata (L.) Wilczek) in a BC(1)F(1) ((JP81610 × TVnu457) × JP81610) population derived from the cross between yardlong bean accession JP81610 and wild cowpea (Vigna unguiculata subsp. unguiculata var. spontanea) accession TVnu457. The markers were clustered into 11 linkage groups (LGs) spanning 852.4 cM in total length with a mean distance between adjacent markers of 3.96 cM. All markers on LG11 showed segregation distortion towards the homozygous yardlong bean JP81610 genotype. The markers on LG11 were also distorted in the rice bean (Vigna umbellata (Thunb.) Ohwi & Ohashi) map, suggesting the presence of common segregation distortion factors in Vigna species on this LG. One major and six minor QTLs were identified for pod length variation between yardlong bean and wild cowpea. Using flanking markers, six of the seven QTLs were confirmed in an F(2) population of JP81610 × TVnu457. The molecular linkage map developed and markers linked to pod length QTLs would be potentially useful for yardlong bean and cowpea breeding.

  20. Nonuniform isotope patterns produced by collision-induced dissociation of homogeneously labeled ubiquitin: implications for spatially resolved hydrogen/deuterium exchange ESI-MS studies.

    Science.gov (United States)

    Ferguson, Peter L; Konermann, Lars

    2008-06-01

    There is an ongoing debate whether collision-induced dissociation (CID) of electrosprayed proteins after solution-phase hydrogen/deuterium exchange (HDX) is a viable approach for determining spatially resolved deuteration patterns. This work explores the use of two methods, source-CID and hexapole tandem mass spectrometry (MS/MS) on a quadrupole time-of-flight (Q-TOF) mass spectrometer, for measuring the fragment deuteration levels of regioselectively labeled ubiquitin. Both methods reveal that b-ions exhibit HDX levels significantly below that of the intact protein, whereas several y'' fragments are labeled to a much greater extent. These results are consistent with earlier source-CID data (Akashi, S.; Naito, Y.; Takio, K. Anal. Chem. 1999, 71, 4974-4980). However, the measured b-ion deuteration levels are in disagreement with the known solution-phase behavior of ubiquitin. Partial agreement is observed for y''-ions. Control experiments on homogeneously labeled ubiquitin (having the same average deuteration level at every exchangeable site) result in highly nonuniform fragment HDX levels. In particular, b-ions exhibit deuteration levels significantly below that of intact ubiquitin, thereby mimicking the behavior seen for the regioselectively labeled protein. This effect is likely caused by isotope fractionation during collisional activation, facilitated by the high mobility of charge carriers (scrambling) in the gas phase. The observation that the b-ion labeling behavior is largely independent of the spatial isotope distribution within solution-phase ubiquitin invalidates these ions as reporters of the protein deuteration pattern. This work questions the common practice of interpreting any nonuniformities in fragment deuteration as being indicative of regioselective solution-phase labeling. Artifactual deuterium enrichment or depletion during collisional activation may have contributed to the current lack of consensus as to whether HDX/CID represents a potentially

  1. Transferability of Mungbean Genomic-SSR Markers in Other Vigna Species%绿豆基因组SSR引物在豇豆属作物中的通用性

    Institute of Scientific and Technical Information of China (English)

    钟敏; 程须珍; 王丽侠; 王素华; 王小宝

    2012-01-01

    Cowpea (Vigna unguiculata L. Walp.), mungbean (V. Radiata L. Wilczek), rice bean [V. Umbellate (Thunb.) Ohwi & Ohashi], and adzuki bean (V; angularis Willd. Ohwi and Ohashi) are major food legumes in China. At present, SSR markers for genetic analysis of these legumes are much limited. Transferability analysis of primers has the vital significance to reduce their development cost and improve their development efficiency. In this study, 1 205 SSR primers were tested for their transferability and polymorphism by PCR amplification with the genomic DNA of four Vigna species, cowpea, adzuki bean, mungbean and rice bean. The results indicated that the transferability rate of mungbean genomic-SSR in cowpea, adzuki bean and rice bean was 50.0%, 73.3%, and 81.6%, and the ratio of polymorphism SSR primers in these crops was 4.1%, 1.7%, and 1.5%, whereas 32.0% in mungbean. A total of 469 mungbean genomic-SSR primers were detected to be highly transferable among different species of Vigna. The transferability of mungbean genomic-SSR was higher in adzuki bean and rice bean than in cowpea. These transferable markers are useful for further genetic and breeding studies in these species.%分子标记的种间通用性可降低其开发成本,提高利用效率,也有助于促进遗传研究较薄弱物种的分子遗传学研究.本文选取绿豆、小豆、豇豆及饭豆材料各3份,分析1205对新开发的绿豆基因组SSR引物在这些材料中的扩增效果,结果显示绿豆基因组SSR引物在豇豆、小豆和饭豆中的通用性比率分别为50.0%、73.3%和81.6%;多态性比率分别为4.1%、1.7%和1.5%;在4个种间均通用的引物469对.这些通用性SSR引物将有助于这4种食用豆类在多样性评价、连锁图谱的构建、基因定位及比较基因组学等方面的研究.

  2. Experimental Urban Heat Island Research of Four Biggest Polar Cities in Northern Hemisphere

    Science.gov (United States)

    Konstantinov, Pavel; Baklanov, Alexander; Varentsov, Mikhail; Kukanova, Evgenia; Repina, Irina; Shuvalov, Sergey; Samsonov, Timofey

    2014-05-01

    Urban Heat Island (UHI) effect is well-known in modern climatology due to its influence on different economic features and urban air quality (Oke, 1987). Also UHI characteristics differs in different climate zones, for example in summer in Mediterranean and subtropical monsoon climate types it leads to growing energy consumption due to AC systems using (Ohashi et al, 2007). But there is only a few papers about UHI (Magee et al, 1999) in high latitudes, for the cities over the Polar Circle and especially about behavior of the heat islands during the polar night, while anthropogenic heat is the main source of thermal energy. The main goal of this study is to mitigate this lack of information about climatology of UHI formation in big cities (with population exceeding 50 000) of Arctic zone. In this paper, we consider the results of experimental research of the UHI of 4 biggest Arctic Cities (Murmansk, Norilsk, Apatity and Vorkuta), which were obtained during the expedition of Russian Geographic Society in 2013-2014. During the project we used a different measurements techniques: 1. Installation of two automatic weather stations (AWS) in rural zone and city center 2. Installation of small temperature sensors (iButton) network in the city and suburbs 3. Regular car-based temperature sounding of the city with AWS. 4. Using MTP-5 microwave temperature profiler. This investigations allowed to collect unique data about UHI in high latitudes. Analysis of the collected data showed the existence of UHI with the difference between city center and surrounding landscape up to few degrees Celcius. UHI characteristics in view of synoptic conditions was analyzed for several typical situations, for some cities (Norilsk) the negative correlation of the UHI power with air temperature was determined. The reported study was supported by RGS (Russian Geographical Society ), research project No.27/2013-NZ References: 1. Magee N., Curtis J., Wendler G., The Urban Heat Island Effect at

  3. The long-term effects of pitavastatin on blood lipids and platelet activation markers in stroke patients: impact of the homocysteine level.

    Directory of Open Access Journals (Sweden)

    Hideki Sugimoto

    Full Text Available To examine the impact of the plasma homocysteine level on the anti-atherosclerotic effects of pitavastatin treatment, we retrospectively examined 59 patients who had a history of stroke and had been prescribed pitavastatin for the treatment of dyslipidemia at the Neurology department of Toho University Ohashi Medical Center Hospital. The patients were classified into two groups according to their homocysteine levels. Carotid artery plaque progression was determined before and after pitavastatin treatment. Plasma levels of high-sensitivity C-reactive protein, platelet molecular markers, and von Willebrand factor were measured. Pitavastatin treatment had beneficial effects on the lipid profiles of these patients and slowed atherosclerosis progression. These effects were observed in both the high and low homocysteine groups. Proactive lipid intervention using pitavastatin may inhibit the progression of atherosclerosis and contribute to secondary prevention of stroke in high-risk patients. We conclude that this statin could inhibit progression at any stage of disease and should therefore be proactively administered to these patient groups, regardless of disease severity.

  4. Spinning test-body orbiting around Schwarzschild black hole: circular dynamics and gravitational-wave fluxes

    CERN Document Server

    Harms, Enno; Bernuzzi, Sebastiano; Nagar, Alessandro

    2016-01-01

    We consider a spinning test-body in circular motion around a nonrotating black hole and analyze different prescriptions for the body's dynamics. We compare, for the first time, the Mathisson-Papapetrou formalism under the Tulczyjew spin-supplementary-condition (SSC), the Pirani SSC and the Ohashi-Kyrian-Semerak SSC, and the spinning particle limit of the effective-one-body Hamiltonian of [Phys.~Rev.~D.90,~044018(2014)]. We analyze the four different dynamics in terms of the ISCO shifts and in terms of the coordinate invariant binding energies, separating higher-order spin contributions from spin-orbit contributions. The asymptotic gravitational wave fluxes produced by the spinning body are computed by solving the inhomogeneous $(2+1)D$ Teukolsky equation and contrasted for the different cases. For small orbital frequencies $\\Omega$, all the prescriptions reduce to the same dynamics and the same radiation fluxes. For large frequencies, ${x \\equiv (M \\Omega)^{2/3} >0.1 }$, where $M$ is the black hole mass, and ...

  5. Comparative study of treatment continuation using second-generation antipsychotics in patients with schizophrenia or schizoaffective disorder

    Directory of Open Access Journals (Sweden)

    Azekawa T

    2011-11-01

    Full Text Available Takaharu Azekawa, Shizuko Ohashi, Akira ItamiShioiri Mental Clinic, Yokosuka-shi, Kanagawa-ken, JapanBackground: Effectiveness of a drug is a key concept dependent on efficacy, safety, and tolerability. Time to discontinuation of treatment is also representative of effectiveness. We investigated differences in treatment discontinuation among newly started second-generation antipsychotics in the clinical setting.Methods: Using a retrospective cohort study design, we screened all outpatients (n = 7936 who visited the Shioiri Mental Clinic between July 1, 2008 and June 30, 2010. We identified a cohort of patients (n = 703 diagnosed with schizophrenia or schizoaffective disorder and calculated the time to discontinuation of each second-generation antipsychotic.Results: Of the 703 patients, 149 were newly treated with aripiprazole, 67 with blonanserin, 95 with olanzapine, 36 with quetiapine, 74 with perospirone, and 120 with risperidone. The time to discontinuation for all causes was significantly longer for aripiprazole than for blonanserin, olanzapine, and risperidone. In addition, aripiprazole tended to be continued for longer than quetiapine and perospirone, but these differences were not significant.Conclusion: Aripiprazole may be considered the best available option for long-term treatment of patients with schizophrenia or schizoaffective disorder.Keywords: retrospective study, second-generation antipsychotics, effectiveness, treatment continuation, schizophrenia, aripiprazole

  6. The activity of Mblk-1, a mushroom body-selective transcription factor from the honeybee, is modulated by the ras/MAPK pathway.

    Science.gov (United States)

    Park, Jung-Min; Kunieda, Takekazu; Kubo, Takeo

    2003-05-16

    We previously identified a gene, termed Mblk-1, that encodes a putative transcription factor with two DNA-binding motifs expressed preferentially in the mushroom body of the honeybee brain, and its preferred binding sequence, termed Mblk-1-binding element (MBE) (Takeuchi, H., Kage, E., Sawata, M., Kamikouchi, A., Ohashi, K., Ohara, M., Fujiyuki, T., Kunieda, T., Sekimizu, K., Natori, S., and Kubo, T. (2001) Insect Mol Biol 10, 487-494; Park, J.-M., Kunieda. T., Takeuchi, H., and Kubo, T. (2002) Biochem. Biophys. Res. Commun. 291, 23-28). In the present study, the effect of Mblk-1 on transcription of genes containing MBE in Drosophila Schneider's Line 2 cells was examined using a luciferase assay. Mblk-1 expression transactivated promoters containing MBEs approximately 2-7-fold. Deletion experiments revealed that RHF2, the second DNA-binding domain of Mblk-1, was necessary for the transcriptional activity. Furthermore, mitogen-activated protein kinase (MAPK) phosphorylated Mblk-1 at Ser-444 in vitro, and the Mblk-1-induced transactivation was stimulated by phosphorylation of Ser-444 by the Ras/MAPK pathway in the luciferase assay. These results suggest that Mblk-1 is a transcription factor that might function in the mushroom body neuronal circuits downstream of the Ras/MAPK pathway in the honeybee brain.

  7. New steel-materials for bridge-construction; Kyoryo yoto no shinkozai oyobi shinkenzai

    Energy Technology Data Exchange (ETDEWEB)

    Sakata, Y.; Fujii, Y.; Suzuki, A.; Takagi, M.; Nishiumi, K.; Kusunoki, T.; Tsuzuki, T.; Usami, A. [Nippon Steel Corp., Tokyo (Japan)

    1998-07-31

    Nippon Steel Corporation is exerting endeavors for the development of various technologies which concern materials, designing, and execution in the field of bridges. Outlined in this report are the merits and effects of some fruits of such endeavors, which involve a new weather-resistant steel to reduce the maintenance cost, longitudinally profiled steel plates to reduce the manufacturing cost, rectangular steel tubes using a high-tenacity steel, long-span-conscious grating slabs and steel elements to save labor in bridge construction, etc. For instance, the newly developed weather-resistant steel is a product intended for use for Japan`s big cities and trunk lines near the seashore, and is so designed as to contain 5% Ni to withstand seashore climate after studies and tests. This steel will contribute to the reduction in the cost for maintaining bridges in seashore belts where the conventional weather-resistant steel does not work effectively or in snowy regions where the use of snow-melting agents is inevitable. In another example, the steel is used for the construction of Nippon Steel Corporation`s Minami-Ohashi Bridge situated in the sea-facing zone of Nagoya Works of the corporation, where tests are still under way. 18 refs., 23 figs., 4 tabs.

  8. Vibration control of tower of long span suspension bridge; Chodai tsuribashi shuto no seishin gijutsu

    Energy Technology Data Exchange (ETDEWEB)

    Kubota, H.; Miyazaki, M. [Sumitomo Heavy Industries, Ltd., Tokyo (Japan); Sasaki, M. [Bridge and Offshore Engineering Association, Tokyo (Japan); Fumoto, K. [Honshu-Shikoku Bridge Authority, Tokyo (Japan)

    1998-08-20

    This paper describes the vibration control during the erection of 8P main tower of Kurushima-ohashi Bridge. Since the body of tower crane and the crane post were adjacent to the main tower, stability against wind due to the change of separation flow was worried. Response characteristics and design data for the damper were obtained through the wind tunnel tests. Since the vibration characteristics change in each erection step, generation of vortex excitation was examined in various modes. An active mass damper (AMD) was applied to the tower surface radial bending primary vibration, of which natural frequency changes in a wide range at the wind velocity below working limit, and the other vibration modes. A tuned mass damper (TMD) was also used in the mode where large damping energy is required under the high wind velocity and high frequency conditions. For the rolling pendulum type AMD, a servo-motor driving carriage moves on the frame rail, and a restitutive force is obtained with rotating the fan type rolling element pin-supported on the carriage. The natural frequency of AMD can be adjusted by fan shaped plural weight plates. Variable gain type DVFB control was employed, in which displacement and velocity of the damper are used as the control output. Sufficient functions could be obtained. 7 refs., 4 figs., 5 tabs.

  9. [Intraductal papillary mucinous neoplasm and recurrent pancreatitis].

    Science.gov (United States)

    Gálvez, Eduardo; Gálvez, Gustavo; Barboza, Aurelio; Barboza, Eduardo; Combe, Juan Manuel; Combe, Mario R; Combe, Juan; Arias Stella C, Javier; Arias Stella, Javier

    2013-01-01

    Ohashi described for the first time the IPMN on 1982 as a pancreatic neoplasia with mucine cells forming papillae and producing dilatation of the main pancreatic duct or its branches. The IPMN represent the 1% of the pancreatic tumors and 5% of the cystic neoplasias. It is potentially malignant in a period of five years being more frequent in males between 60-70 and clinically these patients' presents as acute, recurrent or chronic pancreatitis, with an incidence of malignancy from 25% to 70%. CT scan and cholangio MRI allows the diagnosis, the variety, localization and possibility of determine malignancy. The treatment is the Whipple resection. We are reporting the case of an obese middle age male, being observed along the last 10 years because of recurrent pancreatitis with a cystic lesion of the head of the pancreas. The CT scan, endoscopic-ultrasound and the analysis of the liquid content suggested a mucinous lesion, reason why the patient underwent a pancreatic-duodenal resection. The histology study confirms the diagnosis of IPMN.

  10. Xyloglucan Antibodies Inhibit Auxin-Induced Elongation and Cell Wall Loosening of Azuki Bean Epicotyls but Not of Oat Coleoptiles 1

    Science.gov (United States)

    Hoson, Takayuki; Masuda, Yoshio; Sone, Yoshiaki; Misaki, Akira

    1991-01-01

    Polyclonal antibodies were raised in rabbits against isoprimeverose (Xyl1Glc1), xyloglucan heptasaccharides (Xyl3Glc4), and octasaccharides (Gal1Xyl3Glc4). Antibodies specific for hepta- and octasaccharides suppressed auxin-induced elongation of epicotyl segments of azuki bean (Vigna angularis Ohwi and Ohashi cv Takara). These antibodies also inhibited auxin-induced cell wall loosening (decrease in the minimum stress-relaxation time and the relaxation rate of the cell walls) of azuki segments. However, none of the antibodies influenced auxin-induced elongation or cell wall loosening of coleoptile segments of oat (Avena sativa L. cv Victory). Auxin caused a decrease in molecular mass of xyloglucans in the cell walls of azuki epicotyls and oat coleoptiles. The antibodies inhibited such a change in molecular mass of xyloglucans in both species. Preimmune serum exhibited little or no inhibitory effect on auxin-induced elongation, cell wall loosening, or breakdown of xyloglucans. The results support the view that the breakdown of xyloglucans is associated with the cell wall loosening responsible for auxin-induced elongation in dicotyledons. The view does not appear to be applicable to poaceae, because the inhibition of xyloglucan breakdown by the antibodies did not influence auxin-induced elongation or cell wall loosening of oat coleoptiles. ImagesFigure 1Figure 2 PMID:16668221

  11. A new type of endo-xyloglucan transferase devoted to xyloglucan hydrolysis in the cell wall of azuki bean epicotyls.

    Science.gov (United States)

    Tabuchi, A; Mori, H; Kamisaka, S; Hoson, T

    2001-02-01

    A new type of xyloglucan-degrading enzyme was isolated from the cell wall of azuki bean (Vigna angularis Ohwi et Ohashi cv. Takara) epicotyls and its characteristics were determined. The enzyme was purified to apparent homogeneity by Concanavalin A (Con A)-Sepharose, cation exchange, and gel filtration columns from a cell wall protein fraction extracted with 1 M sodium chloride. The purified enzyme gave a single protein band of 33 kDa on SDS-PAGE. The enzyme specifically cleaved xyloglucans and showed maximum activity at pH 5.0 when assayed by the iodine-staining method. An increase in reducing power in xyloglucan solution was clearly detected after treatment with the purified enzyme. Xyloglucans with molecular masses of 500 and 25 kDa were gradually hydrolyzed to 5 kDa for 96 h without production of any oligo- or monosaccharide with the purified enzyme. The purified enzyme did not show an endo-type transglycosylation reaction, even in the presence of xyloglucan oligosaccharides. Partial amino acid sequences of the enzyme shared an identity with endo-xyloglucan transferase (EXGT) family, especially with xyloglucan endotransglycosylase (XET) from nasturtium. These results suggest that the enzyme is a new member of EXGT devoted solely to xyloglucan hydrolysis.

  12. Hypergravity induces reorientation of cortical microtubules and modifies growth anisotropy in azuki bean epicotyls.

    Science.gov (United States)

    Soga, Kouichi; Wakabayashi, Kazuyuki; Kamisaka, Seiichiro; Hoson, Takayuki

    2006-11-01

    We examined the changes in the orientation of cortical microtubules during the hypergravity-induced modification of growth anisotropy (inhibition of elongation growth and promotion of lateral growth) in azuki bean (Vigna angularis Ohwi et Ohashi) epicotyls. The percentage of cells with transverse microtubules was decreased, while that with longitudinal microtubules was increased, in proportion to the logarithm of the magnitude of gravity. The percentage of cells with longitudinal microtubules showed an increase within 0.5 h of transfer of the 1g-grown seedlings to a 300g-hypergravity condition. Lanthanum and gadolinium, blockers of calcium channels, nullified the modification of growth anisotropy and reorientation of microtubules by hypergravity. Horizontal and acropetal hypergravity modified growth anisotropy and reorientation of microtubules, as did basipetal hypergravity, and these changes were not seen in the presence of lanthanum or gadolinium. These results suggest that hypergravity changes activities of lanthanum- and gadolinium-sensitive calcium channels independently of its direction, which may lead to reorientation of cortical microtubules and modification of growth anisotropy in azuki bean epicotyls.

  13. Graviperception in growth inhibition of plant shoots under hypergravity conditions produced by centrifugation is independent of that in gravitropism and may involve mechanoreceptors.

    Science.gov (United States)

    Soga, Kouichi; Wakabayashi, Kazuyuki; Kamisaka, Seiichiro; Hoson, Takayuki

    2004-04-01

    Hypergravity caused by centrifugation inhibits elongation growth of shoots by decreasing the cell wall extensibility via suppression of xyloglucan breakdown as well as by the thickening of cell walls. The mechanism of graviperception in hypergravity-induced growth inhibition was investigated in Arabidopsis [A. thaliana (L.) Heynh.] hypocotyls and azuki bean (Vigna angularis Ohwi et Ohashi) epicotyls. Hypergravity caused growth suppression in both sgr1-1 and pgm1, which are Arabidopsis mutants deprived of gravitropism, as in wild-type plants, suggesting that the graviperception in hypergravity-induced growth inhibition of shoots is independent of that in gravitropism. Hypergravity had no effects on growth of azuki bean epicotyls or Arabidopsis hypocotyls in the presence of lanthanum or gadolinium, which are blockers of mechanoreceptors. Moreover, lanthanum or gadolinium at the same concentration had no influence on gravitropism of azuki bean epicotyls and Arabidopsis hypocotyls. Hypergravity had no effects on cell wall extensibility and affected neither xyloglucan metabolism nor the thickness of cell walls in the lanthanum- or gadolinium-treated azuki bean epicotyls. Lanthanum or gadolinium inhibited the hypergravity-induced increase in the pH of the apoplastic fluid in the epicotyls, which is involved in the processes of the suppression of xyloglucan breakdown due to hypergravity. These findings suggest that plants perceive the hypergravity stimuli by mechanoreceptors in the plasma membrane, and utilize the perceived signal to regulate the growth rate of their shoots.

  14. Xyloglucan antibodies inhibit auxin-induced elongation and cell wall loosening of azuki bean epicotyls but not of oat coleoptiles.

    Science.gov (United States)

    Hoson, T; Masuda, Y; Sone, Y; Misaki, A

    1991-06-01

    Polyclonal antibodies were raised in rabbits against isoprimeverose (Xyl(1)Glc(1)), xyloglucan heptasaccharides (Xyl(3)Glc(4)), and octasaccharides (Gal(1)Xyl(3)Glc(4)). Antibodies specific for hepta- and octasaccharides suppressed auxin-induced elongation of epicotyl segments of azuki bean (Vigna angularis Ohwi and Ohashi cv Takara). These antibodies also inhibited auxin-induced cell wall loosening (decrease in the minimum stress-relaxation time and the relaxation rate of the cell walls) of azuki segments. However, none of the antibodies influenced auxin-induced elongation or cell wall loosening of coleoptile segments of oat (Avena sativa L. cv Victory). Auxin caused a decrease in molecular mass of xyloglucans in the cell walls of azuki epicotyls and oat coleoptiles. The antibodies inhibited such a change in molecular mass of xyloglucans in both species. Preimmune serum exhibited little or no inhibitory effect on auxin-induced elongation, cell wall loosening, or breakdown of xyloglucans. The results support the view that the breakdown of xyloglucans is associated with the cell wall loosening responsible for auxin-induced elongation in dicotyledons. The view does not appear to be applicable to poaceae, because the inhibition of xyloglucan breakdown by the antibodies did not influence auxin-induced elongation or cell wall loosening of oat coleoptiles.

  15. Suppression of gravitropic response of primary roots by submergence.

    Science.gov (United States)

    Hoson, T; Kamisaka, S; Masuda, Y

    1996-05-01

    Primary roots of six plant species were placed horizontally either in humid air or under water, and their growth and gravitropic responses were examined. In air, all the roots showed a normal gravitropic curvature. Under water without aeration, roots of rice (Oryza sativa L.), oat (Avena sativa L.), azuki bean (Vigna angularis Ohwi et Ohashi), and cress (Lepidium sativum L.) curved downward at almost same rate as in air, whereas the curvature of roots of maize (Zea mays L.) and pea (Pisum sativum L.) was strongly suppressed. Submergence did not cause a decrease in growth rate of these roots. When roots of maize and pea were placed horizontally under water without aeration and then rotated in three dimensions on a clinostat in air, they showed a significant curvature, suggesting that the step suppressed by submergence is not graviperception but the subsequent signal transmission or differential growth process. Constant bubbling of air through the water partly restored the gravitropic curvature of maize roots and completely restored that of pea roots. The curvature of pea roots was also partly restored by the addition of an inhibitor of ethylene biosynthesis, aminooxyacetic acid. In air, ethylene suppressed the gravitropic curvature of roots of maize and pea. Furthermore, the level of ethylene in the intercellular space of the roots was increased by submergence. These results suggest that the accumulation of ethylene in the tissue is at least partly involved in suppression of transmission of the gravity signal or of differential growth in maize and pea roots under conditions of submergence.

  16. Efficacy of multimodal treatment for leptomeningeal metastases in a lung cancer harboring an EGFR mutation

    Directory of Open Access Journals (Sweden)

    Morichika D

    2016-03-01

    Full Text Available Daisuke Morichika,1 Toshio Kubo,2 Hiroko Gotoda,1 Tomoki Tamura,1 Kadoaki Ohashi,1 Katsuyuki Hotta,1 Masahiro Tabata,2 Kazuhiko Kurozumi,3 Mitsune Tanimoto,4 Katsuyuki Kiura1 1Department of Respiratory Medicine, 2Center for Clinical Oncology, Okayama University Hospital, Okayama, Japan; 3Department of Neurological Surgery, 4Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan Abstract: For lung cancer patients with epidermal growth factor receptor (EGFR mutations, the advent of EGFR tyrosine kinase inhibitors (TKIs has prolonged survival rates. Even though disease sites have been well controlled by EGFR-TKIs, some patients develop carcinomatous meningitis, which reduces their quality of life drastically. Although multidisciplinary approaches have improved patient survival and quality of life, the outcomes are not yet satisfactory. We report the case of a 54-year-old Japanese woman diagnosed with leptomeningeal metastases (LM from a lung adenocarcinoma harboring an EGFR exon 21 L858R point mutation. She was treated with gefitinib for 2 months, and symptoms of LM emerged during the treatment period. Although the treatment was switched to erlotinib, disturbance of consciousness worsened because of progressive hydrocephalus. Because all extracranial lesions remained responsive to treatment, and the exon 20 T790M point mutation was not detected in cerebrospinal fluid, we placed a ventriculoperitoneal shunt. The patient’s disturbed consciousness improved dramatically after the shunt was placed; however, the optic and auditory nerve impairments due to direct invasion of LM lesions into nerve canals persisted. Administration of bevacizumab subsequent to whole-brain radiotherapy reduced the cranial nerve impairment, and the patient survived for 10 months. In conclusion, a combination of erlotinib and ventriculoperitoneal

  17. Development of Gene-Based SSR Markers in Rice Bean (Vigna umbellata L. Based on Transcriptome Data.

    Directory of Open Access Journals (Sweden)

    Honglin Chen

    Full Text Available Rice bean (Vigna umbellata (Thunb. Ohwi & Ohashi is a warm season annual legume mainly grown in East Asia. Only scarce genomic resources are currently available for this legume crop species and no simple sequence repeat (SSR markers have been specifically developed for rice bean yet. In this study, approximately 26 million high quality cDNA sequence reads were obtained from rice bean using Illumina paired-end sequencing technology and assembled into 71,929 unigenes with an average length of 986 bp. Of these unigenes, 38,840 (33.2% showed significant similarity to proteins in the NCBI non-redundant protein and nucleotide sequence databases. Furthermore, 30,170 (76.3% could be classified into gene ontology categories, 25,451 (64.4% into Swiss-Prot categories and 21,982 (55.6% into KOG database categories (E-value < 1.0E-5. A total of 9,301 (23.5% were mapped onto 118 pathways using the Kyoto Encyclopedia of Genes and Genome (KEGG pathway database. A total of 3,011 genic SSRs were identified as potential molecular markers. AG/CT (30.3%, AAG/CTT (8.1% and AGAA/TTCT (20.0% are the three main repeat motifs. A total of 300 SSR loci were randomly selected for validation by using PCR amplification. Of these loci, 23 primer pairs were polymorphic among 32 rice bean accessions. A UPGMA dendrogram revealed three major clusters among 32 rice bean accessions. The large number of SSR-containing sequences and genic SSRs in this study will be valuable for the construction of high-resolution genetic linkage maps, association or comparative mapping and genetic analyses of various Vigna species.

  18. Effects of hypergravity on expression of XTH genes in azuki bean epicotyls.

    Science.gov (United States)

    Soga, Kouichi; Wakabayashi, Kazuyuki; Kamisaka, Seiichiro; Hoson, Takayuki

    2007-10-01

    Hypergravity produced by centrifugation caused inhibition of elongation growth and a decrease in the cell wall extensibility in azuki bean epicotyls (Vigna angularis Ohwi et Ohashi). Also, hypergravity increased the molecular mass of xyloglucans, whereas it decreased xyloglucan-degrading activity in epicotyls. When the expression profiles of three xyloglucan endotransglucosylase/hydrolase (XTH) genes, VaXTHS4, VaXTH1 and VaXTH2, were analyzed under hypergravity conditions, the expression of VaXTHS4, which shows only hydrolase activity, was downregulated in proportion to the logarithm of the magnitude of gravity (R = -0.94). However, the gene expression of VaXTH1 or VaXTH2, which shows only transglucosylase activity, was not affected by gravitational conditions. When the seedlings that had been grown at 1 g were transferred to hypergravity conditions at 300 g, the downregulation of VaXTHS4 expression was detected within 1 h. By removal of hypergravity stimulus, VaXTHS4 expression was increased within 1 h. These results suggest that azuki bean epicotyls promptly regulate the expression level of only VaXTHS4 in response to gravity stimuli. The regulation of xyloglucan-hydrolyzing activity as a result of changes in VaXTHS4 expression may be involved in the regulation by gravity of molecular mass of xyloglucans, leading to modifications of cell wall mechanical properties and cell elongation. Lanthanum and gadolinium, potential blockers of mechanosensitive calcium ion permeable channels (mechanoreceptors), nullified the suppression of VaXTHS4 expression, suggesting that mechanoreceptors are responsible for inhibition by hypergravity of VaXTHS4 expression.

  19. Changes in the apoplastic pH are involved in regulation of xyloglucan breakdown of azuki bean epicotyls under hypergravity conditions.

    Science.gov (United States)

    Soga, K; Wakabayashi, K; Hoson, T; Kamisaka, S

    2000-04-01

    Hypergravity inhibited elongation growth of azuki bean (Vigna angularis Ohwi et Ohashi) epicotyls by decreasing the mechanical extensibility of cell walls via the increase in the molecular mass of xyloglucans [Soga et al. (1999) Plant Cell Physiol. 40: 581]. Here, we report that the pH value of the apoplastic fluid in epicotyls increased from 5.8 to 6.6 by hypergravity (300 x g) treatment. When the xyloglucan-degrading enzymes extracted from cell walls of the 1 x g control epicotyls were assayed in buffer at pH 6.6 and 5.8, the activity at pH 6.6 was almost half of that at pH 5.8. In addition, when enzymically active cell wall preparations obtained from 1 x g control epicotyls were autolyzed in buffer at pH 5.8 and 6.6 and then xyloglucans were extracted from the autolyzed cell walls, the molecular mass of xyloglucans incubated at pH 5.8 decreased during the autolysis, while that at pH 6.6 did not change. Thus, the xyloglucans were not depolymerized by autolysis at the pH value (6.6) observed in the hypergravity-treated epicotyls. These findings suggest that in azuki bean epicotyls, hypergravity decreases the activities of xyloglucan-degrading enzymes by increasing the pH in the apoplastic fluid, which may be involved in the processes of the increase in the molecular mass of xyloglucans, leading to the decrease in the cell wall extensibility.

  20. Real-world assessment of diquafosol in dry eye patients with risk factors such as contact lens, meibomian gland dysfunction, and conjunctivochalasis: subgroup analysis from a prospective observational study

    Directory of Open Access Journals (Sweden)

    Yamaguchi M

    2015-12-01

    Full Text Available Masahiko Yamaguchi,1 Takeshi Nishijima,2 Jun Shimazaki,3 Etsuko Takamura,4 Norihiko Yokoi,5 Hitoshi Watanabe,6 Yuichi Ohashi1 1Department of Ophthalmology, Ehime University School of Medicine, Ehime, 2Department of Safety Vigilance Group, Santen Pharmaceutical Co., Ltd., Osaka, 3Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, 4Department of Ophthalmology, School of Medicine, Tokyo Women’s Medical University, Tokyo, 5Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, 6Department of Ophthalmology, Kansai Rosai Hospital, Hyogo, Japan Purpose: To evaluate the efficacy and safety of diquafosol (DQS ophthalmic solution in dry eye (DE patients wearing contact lenses (CLs or with concomitant meibomian gland dysfunction (MGD or conjunctivochalasis in a real-world setting. Patients and methods: From a cohort of patients enrolled in a prospective observational study, DE patients who met the Japanese diagnostic criteria and who received DQS as a monotherapy were extracted and stratified according to the presence or absence of CL use, MGD, and conjunctivochalasis. Corneal and conjunctival fluorescein staining score, tear film break-up time, total symptom score (12 DE-related subjective symptoms, patient-reported outcomes, and adverse reactions were investigated. Results: DQS treatment resulted in significant improvement in total symptom score, corneal and conjunctival fluorescein staining score, and tear film break-up time without significant differences between patient subgroups with versus without CL use, MGD, or conjunctivochalasis. Comparable proportions of patients perceived symptomatic improvements in all subgroups. There were no adverse reactions specifically associated with the CL use or any comorbidity of MGD or conjunctivochalasis. Conclusion: DQS can be used effectively and safely as a monotherapy for the treatment of DE patients wearing CLs or with concomitant MGD or

  1. Quantifying the tensile strength of microbial mats grown over noncohesive sediments.

    Science.gov (United States)

    Vignaga, E; Haynes, H; Sloan, W T

    2012-05-01

    Biofilms in marine and fluvial environments can comprise strong bacterial and diatom mats covering large areas of the bed and act to bind sediments. In this case the bed material becomes highly resistant to shear stresses applied by the overlying fluid motion and detachment, when it does occur, is manifest in patches of biofilm of the order cm(2) being entrained into the flow. This article is the first to report tensile test data specific to the centimeter scale using moist biofilm/sediment composite materials; the strain (ε)-stress (σ) relationships permit quantification of the elasticity (Young's modulus, E) and cohesive strength of each specimen. Specifically, we compare the mechanical strength of cyanobacterial biofilm-only samples to that of biofilm cultured over sediment samples (glass beads or natural sands of d ~ 1 mm) for up to 8 weeks. The range of tensile strength (1,288-3,283 Pa) for composite materials was up to three times higher than previous tensile tests conducted at smaller scale on mixed culture biofilm [Ohashi et al. (1999) Water Sci Technol 39:261-268], yet of similar range to cohesive strength values recorded on return activated sludge flocs [RAS; Poppele and Hozalski (2003) J Microbiol Methods 55:607-615]. Composite materials were 3-6 times weaker than biofilm-only samples, indicating that adhesion to sediment grains is weaker than cohesion within the biofilm. Furthermore, in order to relate the tensile test results to the more common in-situ failure of bio-mats due to shear flow, controlled erosion experiments were conducted in a hydraulic flume with live fluid flow. Here, the fluid shear stress causing erosion was 3 orders of magnitude lower than tensile stress; this highlights both the problem of interpreting material properties measured ex-situ and the need for a better mechanistic model of bio-mat detachment.

  2. Observation of hydrodynamic expansion in a strongly-interacting Fermi gas: Signature of superfluidity?

    Science.gov (United States)

    O'Hara, K. M.; Hemmer, S. L.; Gehm, M. E.; Thomas, J. E.

    2003-05-01

    Atomic Fermi gases with magnetically tunable, strong interactions provide a desktop laboratory for exploring new nonperturbative theories in systems ranging from superconductors to neutron stars. We use all-optical methods to produce a highly degenerate, two-component gas of ^6Li atoms in an applied magnetic field (910 G) near a Feshbach resonance where strong interactions are observed [1]. The s-wave scattering length is estimated to be a_S=-10^4 a_0, which is large compared to the interparticle spacing. Exciting new predictions for this regime include unitarity-limited universal interactions [2] and the onset of resonance superfluidity at a very high transition temperature [3-5]. Forced evaporation is accomplished by lowering the trap laser intensity over a period of 3.5 seconds and then recompressing the trap to full depth. Abrupt release of the cloud at 910 G results in a highly anisotropic expansion, where the gas expands rapidly in the transverse directions while remaining nearly stationary in the axial direction [1]. This anisotropic energy release has been predicted recently to be a signature of superfluidity in a Fermi gas [6]. We will discuss interpretations of the data in terms of superfluidity and unitarity-limited collision dynamics. References 1. K. M. O'Hara et al., Science, 298, 2179 (2002). 2. H. Heiselberg, Phys. Rev. A 63, 043606 (2001). 3. M. Holland, et al., Phys. Rev. Lett. 87, 120406 (2001). 4. E. Timmermans, et al., Phys. Lett. A 285, 228 (2001). 5. Y. Ohashi and A. Griffin, Phys. Rev. Lett. 89, 130402 (2002). 6. C. Menotti, et al., Phys. Rev. Lett. 89, 250402 (2002).

  3. Comparison of the protective effects of seven selected herbs against oxidative stress

    Institute of Scientific and Technical Information of China (English)

    Lee-Wen Chang; Chin-Chen Chu; Heuy-Ling Chu; Horng-Cherng Wu; Pin-Der Duh

    2015-01-01

    Objective:To compare the protective effects of the water extracts of seven herbs, including Solanum indicum L.,Mallotus repandus (Wild) Muell-Arg. (MRM),Bombax malabarica DC (BMDC),Tadehagi triquetrum (L.) Ohashi (TTLO),Clinacanthus nutans(Burm f.) Lindau, Salvia plebeia R. Br (SPRB),Ixeris chinensis Mak (ICM), againsttert-butylhydroperoxide (t-BHP)-induced oxidative stress in Clone 9 cells. Methods: To evaluate the antioxidant properties of water extracts from seven herbs, reducing ability, metal-chelating activity and radical-scavenging activity such as 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical cation and 1,1-diphenyl-2-picrylhydrazyl (DPPH) were determined. In cellular systems,t-BHP was used as a model oxidant to induce oxidative stress. 2′,7′-Dichlorofluorescin diacetate and chloromethylfluorescein-diacetate were used as fluorescence probe to determine reactive oxygen species generation and glutathione level int-BHP-induced Clone 9 cells, respectively. In addition, total tannins, total anthocyanins, total polyphenolics and flavonoids were determined. Results: According to the data obtained from the trolox equivalent antioxidant capacity method,DPPH radical scavenging assay and reducing ability determination,MRM,SPRB, and BMDC showed relatively high antioxidant properties whileTTLO andICM were in the middle andSolanum indicum andClinacanthus nutans had relatively low activity. In cellular model systems,SPRB,BMDC, andTTLO showed higher protective effects againstt-BHP-induced oxidative stress.BMDC,ICM, andTTLO displayed higher inhibitory effects on reactive oxygen species generation int-BHP-induced Clone 9 cells. In addition,SPRB,MRM, andBMDC showed significantly positive modulated glutathione levels. Tannins, anthocyanins, flavonoids and polyphenolics were present in the herbs, which may in part contribute to regulating the oxidative stress. Conclusions: These results indicated that the seven selected herbs may play a crucial role in

  4. Comparison of the protective effects of seven selected herbs against oxidative stress

    Directory of Open Access Journals (Sweden)

    Lee-Wen Chang

    2015-07-01

    Full Text Available Objective: To compare the protective effects of the water extracts of seven herbs, including Solanum indicum L., Mallotus repandus (Wild Muell-Arg. (MRM, Bombax malabarica DC (BMDC, Tadehagi triquetrum (L. Ohashi (TTLO, Clinacanthus nutans (Burm f. Lindau, Salvia plebeia R. Br (SPRB, Ixeris chinensis Mak (ICM, against tert-butylhydroperoxide (t-BHP-induced oxidative stress in Clone 9 cells. Methods: To evaluate the antioxidant properties of water extracts from seven herbs, reducing ability, metal-chelating activity and radical-scavenging activity such as 2,2′-azino-bis(3- ethylbenzothiazoline-6-sulphonic acid radical cation and 1,1-diphenyl-2-picrylhydrazyl (DPPH were determined. In cellular systems, t-BHP was used as a model oxidant to induce oxidative stress. 2′,7′-Dichlorofluorescin diacetate and chloromethylfluorescein-diacetate were used as fluorescence probe to determine reactive oxygen species generation and glutathione level in t-BHP-induced Clone 9 cells, respectively. In addition, total tannins, total anthocyanins, total polyphenolics and flavonoids were determined. Results: According to the data obtained from the trolox equivalent antioxidant capacity method, DPPH radical scavenging assay and reducing ability determination, MRM, SPRB, and BMDC showed relatively high antioxidant properties while TTLO and ICM were in the middle and Solanum indicum and Clinacanthus nutans had relatively low activity. In cellular model systems, SPRB, BMDC, and TTLO showed higher protective effects against t-BHP-induced oxidative stress. BMDC, ICM, and TTLO displayed higher inhibitory effects on reactive oxygen species generation in t-BHP-induced Clone 9 cells. In addition, SPRB, MRM, and BMDC showed significantly positive modulated glutathione levels. Tannins, anthocyanins, flavonoids and polyphenolics were present in the herbs, which may in part contribute to regulating the oxidative stress. Conclusions: These results indicated that the seven

  5. Identifying early Earth microfossils in unsilicified sediments

    Science.gov (United States)

    Javaux, Emmanuelle J.; Asael, Dan; Bekker, Andrey; Debaille, Vinciane; Derenne, Sylvie; Hofmann, Axel; Mattielli, Nadine; Poulton, Simon

    2013-04-01

    The search for life on the early Earth or beyond Earth requires the definition of biosignatures, or "indices of life". These traditionally include fossil molecules, isotopic fractionations, biosedimentary structures and morphological fossils interpreted as remnants of life preserved in rocks. This research focuses on traces of life preserved in unsilicified siliciclastic sediments. Indeed, these deposits preserve well sedimentary structures indicative of past aqueous environments and organic matter, including the original organic walls of microscopic organisms. They also do not form in hydrothermal conditions which may be source of abiotic organics. At our knowledge, the only reported occurrence of microfossils preserved in unsilicified Archean sediments is a population of large organic-walled vesicles discovered in shales and siltstones of the 3.2 Ga Moodies Group, South Africa. (Javaux et al, Nature 2010). These have been interpreted as microfossils based on petrographic and geochemical evidence for their endogenicity and syngeneity, their carbonaceous composition, cellular morphology and ultrastructure, occurrence in populations, taphonomic features of soft wall deformation, and the geological context plausible for life, as well as lack of abiotic explanation falsifying a biological origin. Demonstrating that carbonaceous objects from Archaean rocks are truly old and truly biological is the subject of considerable debate. Abiotic processes are known to produce organics and isotopic signatures similar to life. Spheroidal pseudofossils may form as self-assembling vesicles from abiotic CM, e.g. in prebiotic chemistry experiments (Shoztak et al, 2001), from meteoritic lipids (Deamer et al, 2006), or hydrothermal fluids (Akashi et al, 1996); by artifact of maceration; by migration of abiotic or biotic CM along microfractures (VanZuilen et al, 2007) or along mineral casts (Brasier et al, 2005), or around silica spheres formed in silica-saturated water (Jones and

  6. Outline of the classified system of the Chinese Leguminosae%中国豆科植物分类系统概览

    Institute of Scientific and Technical Information of China (English)

    朱相云

    2004-01-01

    豆科是被子植物中继兰科和菊科之后的第三大科,其中包括三个亚科:即云实亚科、含羞草亚科和蝶形花亚科.本文根据最新资料,整理出世界豆科有42族、634属、17 834种,中国有33族、169属、1 518种(另外含15亚种、167变种和41变型),其中外来种158种(含亚种和变种,隶属于73属).为建立中国豆科植物数据库,本文在Polhill豆科植物分类系统的基础上,结合一些新的资料,提出中国豆科植物系统概要.文中按分类等级进行排序,每一属含有世界和中国种数及分布.%The family Leguminosae (Fabaceae), the largest one of flowering plants after the Compositae (or Asteraceae) and Orchidaceae, consist of three subfamilies such as Caesalpinioideae, Mimosoideae and Papilionoideae. It comprises 42 tribes, 635 genera and 17 840 species in the world based on the present up to date statistic. In China, there are 33 tribes, 169 genera, 1 518 species, 15 subspecies, 167 varieties and 41 forms recorded so far. Of them, 158 exotic species (containing subspecies and varieties) are included, which belong to the 73 genera [1].For constituting a database of Chinese Legume, the outline for classified system of Chinese Leguminosae is summarized here. This paper aims to indicate the system of Chinese Leguminosae with some new taxonomical treatment (the tribes Wisterieae X. Y. Zhu[2] and Poiretieae (Burkart) H. Ohashi[3]) based on the previous system proposed by Polhill & Raven[[4] & Polhill [5]. The number of species and geographical distribution for each genus[3, 4, 6] is shown in this paper. Of them, black letters and numbers stand for the genera and species appearing in China[6~12]. 

  7. 几种中药渣/PP复合材料的制备与性能%Preparation and Properties of Several Chinese Herbs Residues/PP Composites

    Institute of Scientific and Technical Information of China (English)

    冯彦洪; 张叶青; 李向丽; 瞿金平; 何平伟

    2012-01-01

    Chinese herbs, helicteres angustifolia (HA), Tadehagi triquetrum (L.) H. Ohashi (TTO), Euodia lepta (Spreng.) Merr (ELM), and Pogostemon cablin (Blanco) Benth (PCB) were pretreated by steam explosion. The composites were prepared by mixing steam exploded residue of Chinese herbs (RCH) fibers with polypropylene (PP) using maleic anhydride grafted polypropylene (MAPP) as compatilizer so as to realize the high-value use of RCHs. The main components of RCHs were analyzed, and the morphology of steam exploded RCH fibers and tensile- fractured composite surfaces were observed by scanning electron microcopy (SEM). The results show that the fiber bundles of RCHs can be separated into fiber cells by steam-explosion, which can be used as reinforcement materials. RCH fiber species has a great influence on the tensile and flexural properties of composites. Choosing RCHs with high lignified, the low content of hemicellulose and hetero cells is helpful for preparing composites with a good comprehensive performance.%对几种中药渣(山芝麻,葫芦茶,三叉苦,广霍香)进行蒸汽爆破处理,以马来酸酐改性无规共聚聚丙烯(MAPP)作为相容剂,与聚丙烯(PP)复合制备复合材料,实现几种中药渣废弃物资源的高值化利用。分析了各药渣的主要成分,用扫描电镜(SEM)观察药渣及复合材料拉伸断面的形貌。结果表明,蒸汽爆破处理药渣可使纤维束解离出纤维细胞作为增强材料;药渣纤维的种类影响复合材料的拉伸和弯曲性能,选用木质化程度高、半纤维素含量低、杂细胞少的药渣有利于制备出综合性能较好的复合材料。

  8. Analysis of the Rotationally Resolved, Non-Degenerate (a''_1) and Degenerate (e') Vibronic Bands in the tilde{A}^2E'' ← tilde{X}^2A'_2 Transition of NO_3.

    Science.gov (United States)

    Tran, Henry; Miller, Terry A.

    2016-06-01

    The magnitude of the Jahn-Teller (JT) effect in NO_3 has been the subject of considerable research in our group and other groups around the world. The rotational contour of the 4^1_0 vibronic band was first described by Hirota and coworkers using an oblate symmetric top. Near-infrared band of the nitrate radical NO_3 observed by diode laser spectroscopy. J. Chem. Phys., 107:2829, 1997.} Deev et al. argued that an asymmetric top was required to describe the 2^1_0 band, although their spectrum was not completely rotationally resolved. These discrepancies suggest that a rotational analysis will provide considerable experimental information on the geometry of NO_3. Our group has collected high-resolution, rotationally resolved spectra of the vibronic tilde{A}^2E'' ← tilde{X}^2A'_2 transitions. We have completed analysis of the 3^1_0 and 3^1_04^1_0 parallel bands with a_1'' symmetry by using an oblate symmetric top with spin-rotation and centrifugal distortions. Several other parallel bands are now also reasonably understood. This analysis is consistent with a D3h geometry for NO_3. In order to analyze the perpendicular bands with e' symmetry, we have adapted the oblate symmetric top Hamiltonian from the previous analysis to include spin-orbit coupling, coriolis coupling, and Watson Terms (JT distortions) that allow the oblate symmetric top Hamiltonian to transition continuously to the distorted limit of C2v symmetry. Preliminary analysis of the 2^1_0 and 2^1_04^2_0 bands has shown generally good agreement between model and experimental spectra. Our results indicate only modest JT distortions, although we do find evidence of multiple perturbations between these bands and high vibrational levels of the tilde{X} state. We will present our adapted Hamiltonian and the analysis of the 3^1_0, 3^1_04^1_0, 2^1_0, and 2^1_04^2_0 bands. E. Hirota, T. Ishiwata, K. Kawaguchi, M. Fujitake, N. Ohashi, and I. Tanaka. Near-infrared band of the nitrate radical NO_3 observed by diode

  9. Methoxy polyethylene glycol-epoetin beta for anemia with chronic kidney disease

    Directory of Open Access Journals (Sweden)

    Ohashi N

    2012-03-01

    Full Text Available Naro Ohashi1, Yukitoshi Sakao2, Hideo Yasuda1, Akihiko Kato2, Yoshihide Fujigaki11Internal Medicine 1, 2Blood Purification Unit, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, JapanAbstract: Chronic kidney disease (CKD is a risk factor for end-stage renal failure and cardiovascular events. In patients with CKD, anemia is often caused by decreased erythropoietin production relative to hemoglobin levels. As correction of anemia is associated with improved cardiac and renal function and quality of life, erythropoiesis-stimulating agents (ESAs are standard therapy for anemia in CKD patients. However, traditional ESAs such as epoetin or darbepoetin have short half-lives and require frequent administration, dose changes, and close monitoring of hemoglobin concentration to maintain target hemoglobin levels. Methoxy polyethylene glycol-epoetin beta (MPG-EPO is the only ESA that is generated by chemical modification of glycosylated erythropoietin through the integration of one specific, long, linear chain of polyethylene glycol. This ESA induces continuous erythropoietin receptor activation and has a long half-life (approximately 130 hours. Subcutaneous or intravenous administration of MPG-EPO once every 2 weeks or monthly achieved a high hemoglobin response rate in patients with anemia associated with CKD, regardless of whether the patient was undergoing dialysis. According to data from an observational time and motion study, MPG-EPO maintains hemoglobin levels when the same dose is administered, however infrequently. This suggests that compared with the use of traditional ESAs, administration of MPG-EPO reduces the overall time and cost associated with the management of anemia in CKD patients undergoing dialysis. MPG-EPO is generally well tolerated and most adverse events are of mild to moderate severity. The most commonly reported adverse effects are hypertension, nasopharyngitis, and diarrhea. Subcutaneous injection of MPG-EPO is

  10. Hydrogen

    Directory of Open Access Journals (Sweden)

    John O’M. Bockris

    2011-11-01

    Full Text Available The idea of a “Hydrogen Economy” is that carbon containing fuels should be replaced by hydrogen, thus eliminating air pollution and growth of CO2 in the atmosphere. However, storage of a gas, its transport and reconversion to electricity doubles the cost of H2 from the electrolyzer. Methanol made with CO2 from the atmosphere is a zero carbon fuel created from inexhaustible components from the atmosphere. Extensive work on the splitting of water by bacteria shows that if wastes are used as the origin of feed for certain bacteria, the cost for hydrogen becomes lower than any yet known. The first creation of hydrogen and electricity from light was carried out in 1976 by Ohashi et al. at Flinders University in Australia. Improvements in knowledge of the structure of the semiconductor-solution system used in a solar breakdown of water has led to the discovery of surface states which take part in giving rise to hydrogen (Khan. Photoelectrocatalysis made a ten times increase in the efficiency of the photo production of hydrogen from water. The use of two electrode cells; p and n semiconductors respectively, was first introduced by Uosaki in 1978. Most photoanodes decompose during the photoelectrolysis. To avoid this, it has been necessary to create a transparent shield between the semiconductor and its electronic properties and the solution. In this way, 8.5% at 25 °C and 9.5% at 50 °C has been reached in the photo dissociation of water (GaP and InAs by Kainthla and Barbara Zeleney in 1989. A large consortium has been funded by the US government at the California Institute of Technology under the direction of Nathan Lewis. The decomposition of water by light is the main aim of this group. Whether light will be the origin of the post fossil fuel supply of energy may be questionable, but the maximum program in this direction is likely to come from Cal. Tech.

  11. Impact of combined pulmonary fibrosis and emphysema on surgical complications and long-term survival in patients undergoing surgery for non-small-cell lung cancer

    Directory of Open Access Journals (Sweden)

    Hata A

    2016-06-01

    Full Text Available Atsushi Hata,1,2 Yasuo Sekine,1 Ohashi Kota,1 Eitetsu Koh,1 Ichiro Yoshino2 1Department of Thoracic Surgery, Tokyo Women’s Medical University Yachiyo Medical Centre, Yachiyo, 2Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba City, Chiba, Japan Purpose: The outcome of radical surgery for lung cancer was investigated in patients with combined pulmonary fibrosis and emphysema (CPFE. Methods: A retrospective chart review involved 250 patients with lung cancer who underwent pulmonary resection at Tokyo Women’s Medical University Yachiyo Medical Center between 2008 and 2012. Based on the status of nontumor-bearing lung evaluated by preoperative computed tomography (CT, the patients were divided into normal, emphysema, interstitial pneumonia (IP, and CPFE groups, and their clinical characteristics and surgical outcome were analyzed. Results: The normal, emphysema, IP, and CPFE groups comprised 124 (49.6%, 108 (43.2%, seven (2.8%, and eleven (4.4% patients, respectively. The 5-year survival rate of the CPFE group (18.7% was significantly lower than that of the normal (77.5% and emphysema groups (67.1% (P<0.0001 and P=0.0027, respectively but equivalent to that of the IP group (44.4% (P=0.2928. In a subset analysis of cancer stage, the 5-year overall survival rate of the CPFE group in stage I (n=8, 21.4% was also lower than that of the normal group and emphysema group in stage I (n=91, 84.9% and n=70, 81.1%; P<0.0001 and P<0.0001, respectively. During entire observation period, the CPFE group was more likely to die of respiratory failure (27.2% compared with the normal and emphysema groups (P<0.0001. Multivariate analysis of prognostic factors using Cox proportional hazard model identified CPFE as an independent risk factor (P=0.009. Conclusion: CPFE patients have a poorer prognosis than those with emphysema alone or with normal lung on CT finding. The intensive evaluation of preoperative CT images is

  12. Heat Exchanger Design Options and Tritium Transport Study for the VHTR System

    Energy Technology Data Exchange (ETDEWEB)

    Chang H. Oh; Eung S. Kim

    2008-09-01

    This report presents the results of a study conducted to consider heat exchanger options and tritium transport in a very high temperature reactor (VHTR) system for the Next Generation Nuclear Plant Project. The heat exchanger options include types, arrangements, channel patterns in printed circuit heat exchangers (PCHE), coolant flow direction, and pipe configuration in shell-and-tube designs. Study considerations include: three types of heat exchanger designs (PCHE, shell-and-tube, and helical coil); single- and two-stage unit arrangements; counter-current and cross flow configurations; and straight pipes and U-tube designs in shell-and-tube type heat exchangers. Thermal designs and simple stress analyses were performed to estimate the heat exchanger options, and the Finite Element Method was applied for more detailed calculations, especially for PCHE designs. Results of the options study show that the PCHE design has the smallest volume and heat transfer area, resulting in the least tritium permeation and greatest cost savings. It is theoretically the most reliable mechanically, leading to a longer lifetime. The two-stage heat exchanger arrangement appears to be safer and more cost effective. The recommended separation temperature between first and second stages in a serial configuration is 800oC, at which the high temperature unit is about one-half the size of the total heat exchanger core volume. Based on simplified stress analyses, the high temperature unit will need to be replaced two or three times during the plant’s lifetime. Stress analysis results recommend the off-set channel pattern configuration for the PCHE because stress reduction was estimated at up to 50% in this configuration, resulting in a longer lifetime. The tritium transport study resulted in the development of a tritium behavior analysis code using the MATLAB Simulink code. In parallel, the THYTAN code, previously performed by Ohashi and Sherman (2007) on the Peach Bottom data, was revived

  13. Safety and efficacy of switching from dorzolamide 1.0%/timolol maleate 0.5% eye drops to brinzolamide 1.0%/timolol maleate 0.5% eye drops

    Directory of Open Access Journals (Sweden)

    Inoue K

    2015-04-01

    Full Text Available Kenji Inoue,1 Minako Shiokawa,1 Kyoko Ishida,2 Goji Tomita2 1Inouye Eye Hospital, Tokyo, Japan; 2Department of Ophthalmology, Toho University Ohashi Medical Center, Tokyo, Japan Purpose: To evaluate the safety and efficacy of switching from dorzolamide 1.0%/timolol maleate 0.5% fixed-combination (DTFC eye drops to brinzolamide 1.0%/timolol maleate 0.5% fixed-combination (BTFC eye drops in patients with primary open-angle glaucoma or ocular hypertension. Methods: A total of 35 eyes of 35 patients with primary open-angle glaucoma or ocular hypertension using DTFC eye drops were included. Participants discontinued DTFC drops and immediately began using BTFC drops. All other eye drops currently being used were continued. Intraocular pressure (IOP 1 and 3 months after switching medications was compared with baseline IOP. One month after switching medications, participant preference and adherence were evaluated. Adverse reactions were monitored at each study visit. Results: The IOP was 17.9±2.6 mmHg at baseline and 18.3±4.1 mmHg and 17.8±3.4 mmHg 1 month and 3 months after switching medications, respectively (P=0.633. The frequency of missing a dose was not different before (6.1% and after (6.1% switching to BTFC. Significantly fewer participants reported stinging after switching to BTFC (15.2% than while using DTFC (51.5%, P<0.01. Blurred vision was reported with the same frequency before (39.4% and after (42.4% switching to BTFC. A total of 33.3% and 27.3% of patients preferred DTFC and BTFC, respectively. Several patients withdrew from the study because of discomfort (n=2, 5.7%, discharge (n=1, 2.9%, dizziness (n=1, 2.9%, or increased IOP (n=2, 5.7%. Conclusion: Switching from DTFC to BTFC was well tolerated and did not result in IOP changes or a decreased patient adherence. When glaucoma patients complain of stinging with DTFC administration, switching to BTFC is an acceptable treatment option. Keywords: brinzolamide/timolol fixed

  14. Accretion-powered Compact Binaries

    Science.gov (United States)

    Mauche, Christopher W.

    2003-12-01

    Preface; The workshop logo; A short history of the CV workshop F. A. Córdova; Part I. Observations: 1. Low mass x-ray binaries A. P. Cowley, P. C. Schmidtke, D. Crampton, J. B. Hutchings, C. A. Haswell, E. L. Robinson, K. D. Horne, H. M. Johnston, S. R. Kulkarni, S. Kitamoto, X. Han, R. M. Hjellming, R. M. Wagner, S. L. Morris, P. Hertz, A. N. Parmar, L. Stella, P. Giommi, P. J. Callanan, T. Naylor, P. A. Charles, C. D. Bailyn, J. N. Imamura, T. Steiman-Cameron, J. Kristian, J. Middleditch, L. Angelini and J. P. Noris; 2. Nonmagnetic cataclysmic variables R. S. Polidan, C. W. Mauche, R. A. Wade, R. H. Kaitchuck, E. M. Schlegel, P. A. Hantzios, R. C. Smith, J. H. Wood, F. Hessman, A. Fiedler, D. H. P. Jones, J. Casares, P. A. Charles, J. van Paradijs, E. Harlaftis, T. Naylor, G. Sonneborn, B. J. M. Hassall, K. Horne, C. A. la Dous, A. W. Shafter, N. A. Hawkins, D. A. H. Buckley, D. J. Sullivan, F. V. Hessman, V. S. Dhillon, T. R. Marsh, J. Singh, S. Seetha, F. Giovannelli, A. Bianchini, E. M. Sion, D. J. Mullan, H. L. Shipman, G. Machin, P. J. Callanan, S. B. Howell, P. Szkody, E. M. Schlegel and R. F. Webbink; 3. Magnetic cataclysmic variables C. Hellier, K. O. Mason, C. W. Mauche, G. S. Miller, J. C. Raymond, F. K. Lamb, J. Patterson, A. J. Norton, M. G. Watson, A. R. King, I. M. McHardy, H. Lehto, J. P. Osborne, E. L. Robinson, A. W. Shafter, S. Balachandran, S. R. Rosen, J. Krautter, W. Buchholz, D. A. H. Buckley, I. R. Tuoly, D. Crampton, B. Warner, R. M. Prestage, B. N. Ashoka, M. Mouchet, J. M. Bonnet-Bidaud, J. M. Hameury, P. Szkody, P. Garnavich, S. Howell, T. Kii, M. Cropper, K. Mason, J. Bailey, D. T. Wickramasinghe, L. Ferrario, K. Beuermann, A. D. Schwope, H.-C. Thomas, S. Jordan, J. Schachter, A. V. Filippenko, S. M. Kahn, F. B. S. Paerels, K. Mukai, M. L. Edgar, S. Larsson, R. F. Jameson, A. R. King, A. Silber, R. Remillard, H. Bradt, M. Ishida, T. Ohashi and G. D. Schmidt; Part II. Accretion Theory: 4. Nonmagnetic W. Kley, F. Geyer, H. Herold, H

  15. Proceedings of the 9th International Symposium on Foundations of Quantum Mechanics in the Light of New Technology

    Science.gov (United States)

    Ishioka, Sachio; Fujikawa, Kazuo

    2009-06-01

    Committee -- Obituary: Professor Sadao Nakajima -- Opening address / H. Fukuyama -- Welcoming address / N. Osakabe -- Cold atoms and molecules. Pseudopotential method in cold atom research / C. N. Yang. Symmetry breaking in Bose-Einstein condensates / M. Ueda. Quantized vortices in atomic Bose-Einstein condensates / M. Tsubota. Quantum degenerate gases of Ytterbium atoms / S. Uetake ... [et al.]. Superfluid properties of an ultracold fermi gas in the BCS-BEC crossover region / Y. Ohashi, N. Fukushima. Fermionic superfluidity and the BEC-BCS crossover in ultracold atomic fermi gases / M. W. Zwierlein. Kibble-Zurek mechanism in magnetization of a spinor Bose-Einstein condensate / H. Saito, Y. Kawaguchi, M. Ueda. Quasiparticle inducing Josephson effect in a Bose-Einstein condensate / S. Tsuchiya, Y. Ohashi. Stability of superfluid fermi gases in optical lattices / Y. Yunomae ... [et al.]. Z[symbol] symmetry breaking in multi-band bosonic atoms confined by a two-dimensional harmonic potential / M. Sato, A. Tokuno -- Spin hall effect and anomalous hall effect. Recent advances in anomalous hall effect and spin hall effect / N. Nagaosa. Topological insulators and the quantum spin hall effect / C. L. Kane. Application of direct and inverse spin-hall effects: electric manipulation of spin relaxation and electric detection of spin currents / K. Ando, E. Saitoh. Novel current pumping mechanism by spin dynamics / A. Takeuchi, K. Hosono, G. Tatara. Quantum spin hall phase in bismuth ultrathin film / S. Murakami. Anomalous hall effect due to the vector chirality / K. Taguchi, G. Tatara. Spin current distributions and spin hall effect in nonlocal magnetic nanostructures / R. Sugano ... [et al.]. New boundary critical phenomenon at the metal-quantum spin hall insulator transition / H. Obuse. On scaling behaviors of anomalous hall conductivity in disordered ferromagnets studied with the coherent potential approximation / S. Onoda -- Magnetic domain wall dynamics and spin related

  16. Ordered supramolecular assembly of bis[3,4,12,13,21,22,30, 31-octa(dodecylthio)-2,3-naphthalocyaninato] erbium at the air/water interface

    Institute of Scientific and Technical Information of China (English)

    CHEN; Ya; nli

    2001-01-01

    [1]Padilla. P, Hatfield, W. E., Correlation between π-orbital overlap and conductivity in bis-phthalocyaninato lanthanides, Inorg. Chim. Acta, 1991,185:131.[2]Passard, M., Blanc, J. P., Malaysson, C., Gaseous oxidation and compensation reduction of lutetium bis-phthalocyanine and lutetium phthalo-naphthalocyanine films, Thin Solid Films, 1995, 271: 8,[3]Besbes. S., Plichon, V., Simon, J. et al., Electromism of octaalkoxymethyl-substituted lutetium diphthalocyanine, J. Electroanal. Chem., 1987, 237:61.[4]Petty. M., Lovett, D. R., O'Connor, J. M., Electrochromism in ytterbium bisphthalocyanine-(steafic acid or cadmium stearate)films deposited by the Langmuir-Blodgett technique, Thin Solid Films, 1989, 179: 387.[5]Souto, J.. Aroca, R.. DeSaja, J. A., Gas adsorption and electrical conductivity of Langmuir-Blodgett films of terbium bisphthalocyanine, J. Phys. Chem., 1994, 98: 8998.[6]Rroca, R.. Bolourchi, H., Battisti, D. et al., Gas adsorption and electrical properties of two Langmuir-Blodgett layers of cerium bisphthalocyanine, Langmuir, 1993, 9: 3138.[7]Konami, H., Hatano, M., Kobayashi, N., Redox potentials of a series of lanthanide-bisphthalocyanine sandwich complexes, Chem. Phys. Lett.. 1990, 165: 397.[8]Koike. N.. Uekusa, H., Ohashi, Y., Relationship between the skew angle and interplanar distance in four bis (phthalocyaninato) lanthanide (Ⅲ) tetrabutyl-ammonium salts ([Nbu"4][Ln"Pc2]; Ln = Nd, Gd, Ho, Lu), Inorg. Chem., 1996, 35:5798.[9]Dennis. K. P. N., Jiang, J., Sandwich-type heteroleptic phthalocyaninato and porphyrinato metal complexes, Chem. Soc. Rev.. 1997, 26: 433.[10]Jiang. J., Liu, W., Poon, Ka-Wo. et al., Synthesis, spectroscopic, and electrochemical properties of rare earth double-deckers with tetra(teft-butyl) 2,3-naphthalocyaninato ligands, Eur. J, Inorg. Chem., 2000: 205.[11]Jiang, J.. Llew, R., Dennis, P. et al., Raman spectroscopic characteristics of phthalocyanine and naphthalocyanine in sandwich

  17. Cancer incidence and novel therapies developed in Japan

    Directory of Open Access Journals (Sweden)

    Masaru Iwasaki

    2012-01-01

    Oncology. JMAJ 54(1: 44–46, 20114.Hildebrandt B, Wust P, Ahlers O, et al. The cellular and molecular basis of hyperthermia. Critical Reviews in Oncology/Hematology 2002; 43(1:33–56.5.Levin WP, Kooy H, Loeffler JS, DeLaney TF. Proton beam therapy. Br J Cancer.2005; 93(8:849-54. 6.Widakowich C, de Castro G Jr, de Azambuja E, Dinh P, Awada A. Review: side effects of approved molecular targeted therapies in solid cancers. Oncologist. 2007; 12(12:1443-55.7.Egawa K. Immuno-cell therapy of cancer in Japan. Anticancer Res. 2004;24(5C:3321-6. 8.Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, Shimada K, Sakamoto M, Hirohashi S, Ohashi Y, Kakizoe T. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet. 2000; 356(9232:802-7. 9.Kimura H, Yamaguchi Y. A phase III randomized study of interleukin-2 lymphokine-activated killer cell immunotherapy combined with chemotherapy or radiotherapy after curative or noncurative resection of primary lung carcinoma. Cancer. 1997;80(1:42-9. 10.Kono K, Takahashi A, Ichihara F, Amemiya H, Iizuka H, Fujii H, Sekikawa T, Matsumoto Y: Prognostic significance of adoptive immunotherapy with tumor-associated lymphocytes in patients with advanced gastric cancer: a randomized trial. Clin Cancer Res. 2002; 8: 1767-71. 11.Fujita K, Ikarashi H, Takakuwa K, Kodama S, Tokunaga A, Takahashi T, Tanaka K. Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes. Clin Cancer Res. 1995; 1(5:501-7.12.Goto S, Shirotani N, Hatakeyama M, Tagami C, Arakawa H, Kuwata E, Noguchi K, Egawa K. Clinical benefit of non-toxic therapy in patients with advanced cancer (opinion. Anticancer Res. 2002; 22(4:2461-4.

  18. EDITORIAL: Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010) Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010)

    Science.gov (United States)

    Takahashi, M.; Saito, H.

    2011-02-01

    overseas. The programme involved 4 plenary talks, 37 invited talks, 85 contributed talks and 352 posters. All submitted papers were reviewed in order to meet the standards of Journal of Physics D: Applied Physics and Journal of Physics: Conference Series. We are grateful to all participants for their valuable contributions and active discussions. We gratefully acknowledge the financial support of 17 Japanese companies and 7 Japanese foundations. Invited papers from ISAMMA 2010 Contents Current status and recent topics of rare-earth permanent magnets S Sugimoto Alloying effect on the magnetic properties of RFeB-type bulk magnets H W Chang, C C Hsieh, J Y Gan, Y T Cheng, M F Shih and W C Chang Coercivity distributions in Nd-Fe-B sintered magnets produced by the grain boundary diffusion process H Nakamura, K Hirota, T Ohashi and T Minowa Recent progress in high Bs Fe-based nanocrystalline soft magnetic alloys M Ohta and Y Yoshizawa Electric-field effects on magnetic anisotropy in Pd/Fe/Pd(0 0 1) surface Shinya Haraguchi, Masahito Tsujikawa, Junpei Gotou and Tatsuki Oda Gate modulation of spin precession in a semiconductor channel Hyun Cheol Koo, Jae Hyun Kwon, Jonghwa Eom, Joonyeon Chang, Suk Hee Han and Mark Johnson Ferromagnetic resonance of epitaxial Fe nanodots grown on MgO measured using coplanar waveguides M Mizuguchi and K Takanashi Switching phase diagrams of current-induced magnetization switching in asymmetric MgO-based magnetic tunnel junctions Seung-Young Park, Jae-Ho Han, Se-Chung Oh, Jang-Eun Lee, Kyung-Tae Nam, Hyun-Woo Lee, Younghun Jo and Kyung-Jin Lee Temperature dependence of spin-dependent transport properties of Co2MnSi-based current-perpendicular-to-plane magnetoresistive devices Y Sakuraba, K Izumi, S Bosu, K Saito and K Takanashi Adsorbate-induced spin-polarization enhancement of Fe3O4(0 0 1) A Pratt, M Kurahashi, X Sun and Y Yamauchi Antiferromagnetic coupling between spinel ferrite and α-Fe layers in Fe3-δO4/MgO/Fe(0 0 1) epitaxial films Hideto

  19. Hurdles overcome in technology transfer for AIET and Positive outcome in Indian patients

    Directory of Open Access Journals (Sweden)

    Dedeepiya V

    2012-01-01

    experienced. An increase in awareness about this least toxic method of Cancer treatment among physicians and the public for an early referral is necessary. Further studies on prevention of cancer using in vitro expanded autologous immune cells are underway. References: 1.Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, Shimada K, Sakamoto M, Hirohashi S, Ohashi Y, Kakizoe T. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet. 2000 ;356(9232:802-7. 2.Kimura H, Yamaguchi Y. A phase III randomized study of interleukin-2 lymphokine-activated killer cell immunotherapy combined with chemotherapy or radiotherapy after curative or noncurative resection of primary lung carcinoma. Cancer. 1997;80(1:42-9. 3.Kono K, Takahashi A, Ichihara F, Amemiya H, Iizuka H, Fujii H, Sekikawa T, Matsumoto Y: Prognostic significance of adoptive immunotherapy with tumor-associated lymphocytes in patients with advanced gastric cancer: a randomized trial. Clin Cancer Res. 2002; 8 : 1767-71. 4.Fujita K, Ikarashi H, Takakuwa K, Kodama S, Tokunaga A, Takahashi T, Tanaka K. Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes. Clin Cancer Res. 1995;1(5:501-7.5.Sivaraman G, Pandian A, Baskar S, Senthil KR, Senthilnagarajan R, Dedeepiya V, Abraham S. Autologous Immune Enhancement therapy for advanced carcinoma of pancreas a case report. PASRM 2008-004. J Stem Cells Regen Med. 2008; 4(1:136.Damodar S, Terunuma H , Sheriff AK , Farzana L , Manjunath S , Senthilkumar R , Shastikumar G , Abraham S , Wang FS. Autologous Immune Enhancement Therapy (AIET for a Case of Acute Myeloid Leukemia (AML - Our Experience. PASRM 2006-001. J Stem Cells Regen Med. 2006, 1(1: 40-417.Takada M, Terunuma H, Deng X, Dewan MZ, Saji S, Kuroi K, Yamamoto N, Toi M. Refractory lung metastasis from breast cancer treated with multidisciplinary therapy including an

  20. Autologous Immune Enhancement Therapy for Cancer - Our experience since 2004

    Directory of Open Access Journals (Sweden)

    Hiroshi Terunuma

    2012-01-01

    disease (SD, whereas 18 had progressive disease (PD. Disease control rate was 66% including CR, PR and SD. After treatment for six months, the objective responses and disease control rate were 25% and 52%, respectively. There were no adverse effects in any of these patients. [17] Conclusion: Cancer has to be tackled with a multipronged approach and combining NK cell and CTL cell based AIET with conventional modalities of treatments such as Surgery, Chemotherapy and Radiotherapy as well as other modalities like Hyperthermia, Proton Beam therapy and low dose chemotherapy is effective even in advanced cancers which are refractory to conventional therapeutic modalities. References: 1.Rosenberg SA, Rapp HJ. Intralesional immunotherapy of melanoma with BCG. Med Clin North Am. 1976 May;60(3:419-30.2.Mazumder A, Eberlein TJ, Grimm EA, Wilson DJ, Keenan AM, Aamodt R, Rosenberg SA. Phase I study of the adoptive immunotherapy of human cancer with lectin activated autologous mononuclear cells. Cancer. 1984 Feb 15;53(4:896-9053.Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, Shimada K, Sakamoto M, Hirohashi S, Ohashi Y, Kakizoe T. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet. 2000 ;356(9232:802-7.4.Sloan AE, Dansey R, Zamorano L, Barger G, Hamm C, Diaz F, Baynes R, Wood G. Adoptive immunotherapy in patients with recurrent malignant glioma: preliminary results of using autologous whole-tumor vaccine plus granulocyte-macrophage colony-stimulating factor and adoptive transfer of anti-CD3-activated lymphocytes. Neurosurg Focus. 2000; 9(6:e9.5.Recchia F, Candeloro G, Di Staso M, Necozione S, Bisegna R, Bratta M, Tombolini V, Rea S. Maintenance immunotherapy in recurrent or metastatic squamous cell carcinoma of the head and neck. J Immunother. 2008; 31(4:413-9.6.Wright SE, Rewers-Felkins KA, Quinlin IS, Phillips CA, Townsend M, Philip R, Dobrzanski MJ, Lockwood-Cooke PR, Robinson W. Cytotoxic