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Sample records for ajustados ajusted clinical

  1. Los adjusted clinicals groups: Un sistema de clasificación de pacientes por ajuste de riesgos

    Directory of Open Access Journals (Sweden)

    Antonio Sicras-Mainar

    2013-06-01

    Full Text Available Los Adjusted Clinical Groups (ACG son un sistema de ajuste de riesgos que clasifica a las personas según su edad y sexo y las condiciones médicas que presentan, y estas personas tienen un consumo similar de recursos sanitarios durante un periodo. Fueron desarrollados por Starfield y Weiner (Universidad Johns Hopkins, EE. UU. 1991, y su objetivo es medir el grado de enfermedad en poblaciones de pacientes basándose en sus niveles de comorbilidad. Entre sus principales aplicaciones destacan: a evaluar la eficiencia en la utilización de los servicios sanitarios, b medir la comorbilidad de la población, y c programar la financiación o pago capitativo para grupos de proveedores. Entre las ventajas del sistema ACG destaca la necesidad de un número limitado de variables para cada paciente (edad, sexo y diagnósticos y que la unidad de medida es el paciente. Se comentan algunas características de este sistema de ajuste de riesgos poblacionales.

  2. Ajuste lineal mediante Microsoft Excel

    OpenAIRE

    Borrás Falomir, Luis; Martí Ortega, Nuria

    2013-01-01

    En este vídeo se muestra cómo utilizar la hoja de cálculo Excel de Microsoft para realizar un ajuste lineal de una serie de puntos. El vídeo detalla cómo obtener los parámetros de la ecuación lineal gráficamente y utilizando las funciones predefinidas de Excel, desarrollado para el Proyecto de Innovación Educativa Innovación Docente en Ingeniería Química (IDIQ).

  3. Ajuste escolar, rechazo y violencia en adolescentes.

    OpenAIRE

    Martínez Ferrer, Belén

    2009-01-01

    RESUMEN El objetivo general de esta tesis doctoral es analizar las relaciones existentes entre el contexto familiar, el escolar y la autoestima, en la predicción de tres indicadores de ajuste adolescente (ajuste escolar, rechazo escolar entre iguales y violencia/victimización escolar). Las variables consideradas en la investigación son: 1. Variables escolares: violencia escolar, victimización, rechazo entre iguales, actitud hacia la autoridad, actitud hacia la transgresión, actitud haci...

  4. Años de vida ajustados por calidad: evolución, fundamentos e implicaciones

    OpenAIRE

    Liliana Chicaíza Becerra; Mario García Molina; Giancarlo Romano Gómez

    2013-01-01

    Los años de vida ajustados por calidad - AVAC o QALY (en su sigla en inglés) - son una medida de resultados en salud que permite hacer comparaciones entre tratamientos con el fin de facilitar escogencias. A partir del desarrollo histórico de esta noción, se presenta su fundamento en las medidas de calidad de vida y en la teoría de utilidad esperada y los problemas derivados de los instrumentos de medición, en particular su fundamentación teórica, su facilidad de implementación y su falta de c...

  5. Estilos relacionales parentales y ajuste adolescente

    OpenAIRE

    Oliva Delgado, Alfredo; Parra Jiménez, Agueda; Arranz Freijo, Enrique

    2008-01-01

    En este artículo se presentan los resultados de un estudio realizado sobre una muestra de 848 adolescentes de edades comprendidas entre los 12 y los 17 años, que cumplimentaron un cuestionario que incluía una escala con 6 dimensiones sobre su percepción del estilo parental o relacional materno y paterno y otros instrumentos para evaluar el ajuste adolescente. La realización de un análisis de conglomerados a partir de las puntuaciones en las 6 dimensiones que componían la escala re...

  6. AJUSTE DE MODELOS DE ELEMENTOS FINITOS

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    WILLIAM VÉLEZ

    2009-01-01

    Full Text Available El método del elemento finito es utilizado en todo el mundo como herramienta para analizar el comportamiento dinámico de sistemas estructurales. Sin embargo, se sabe que las predicciones efectuadas con el uso de modelos construidos empleando dicho método difieren de los resultados experimentales obtenidos a partir de ensayos de vibración en estructuras existentes. El área conocida en lengua inglesa como Model Updating, o Ajuste de Modelos, como se denomina en este documento, surgió como respuesta a dicha problemáticay apunta a efectuar correcciones paramétricas en los modelos de elementos finitos con el fin de lograr que las propiedades dinámicas analíticas se asemejen a sus contrapartes experimentales. El avance de esta disciplina durante los últimos veinte años ha sido vertiginoso; sin embargo, en el medio latinoamericano, y en particular en el colombiano, existe una difusión pobre de dicha temática. Este artículo presenta una revisión del estado del arte a la fecha de su publicación. Se espera que el presente trabajo motive la investigación en el campo del Ajuste de Modelos en centros diferentes a aquellos donde se ha concentrado hasta ahora el desarrollo de esta área y que a su vez provea información suficiente para que el sector industrial latinoamericano incluya dicha tecnología en sus prácticas.

  7. Comparación entre Factores de Ajuste Multiplicativos y Aditivos para Producción por Lactancia en un Hato Holstein

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    Arboleda Zapata Elkin Mauricio

    1995-09-01

    Full Text Available La presente investigación se efectuó a partir de 558 registros de lactancia tomados del hato Holstein Paysandú el cual está situado en el corregimiento Santa Elena de Medellín en una zona ecológica de bosque húmedo montano bajo (bh-MB y pertenece a la Facultad de Ciencias Agropecuarias de la Universidad Nacional de Colombia, Sede Medellín. El objetivo propuesto fué determinar las ventajas comparativas entre factores de ajuste multiplicativos y aditivos para producción por lactancia. Para ello se trabajó con datos ajustados a 305 días, en vista de la muy alta significancia observada para el efecto duración de la lactancia. Después de confirmar por medio del programa de mínimos cuadrados de Harvey, 1988, que los factores medio-ambientales más influyentes sobre la producción ajustada a 305 días son el año de parto, los días abiertos previos y el número de partos (P£0.01, así como la edad y la época de parto (P£0.05, se procedió a ajustar por estos efectos mediante factores de corrección multiplicativos y aditivos. Inicialmente se utilizó como base la subclase de máxima producción para cada efecto y a ellas fueron llevados los demás registros; luego se obtuvieron factores aditivos mediante el uso de constantes estimadas por el programa Harvey y multiplicativos a partir de la media de mínimos cuadrados. Una vez ajustados los datos se corrió nuevamente el modelo inicial, con el fin de cuantificar la varianza residual presente tanto para factores de ajuste multiplicativos como aditivos, a los dos niveles propuestos. La comparación se realizó mirando las relaciones de la tabla F y las varianzas residuales entre grupos y dentro de ellos. Aunque no se presentaron diferencias marcadas, se observa que, en general los factores de ajuste aditivos tuvieron un mejor comportamiento que los multiplicativos, pues con el empleo de estos últimos queda una pequeña variación sin remover; en tanto que con factores de ajuste

  8. LA POLÍTICA SOCIAL EN TIEMPOS DE AJUSTE

    OpenAIRE

    Leonardo Garnier Rímolo

    2011-01-01

    La política social está nuevamente de moda. Hace unos años, eran la estabilización y el ajuste los temas que dominaban la literatura, los debates y hasta las conversaciones de los economistas. Hoy, es cada vez más frecuente la referencia a la pobreza, el costo social del ajuste, el rostro humano de la política económica, el gasto social, la salud, la educación, en fin, todos aquellos temas relativos a la calidad de vida y el desarrollo humano. A diferencia del pasado, sin embargo, este redesc...

  9. LA POLÍTICA SOCIAL EN TIEMPOS DE AJUSTE

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    Leonardo Garnier Rímolo

    2011-09-01

    Full Text Available La política social está nuevamente de moda. Hace unos años, eran la estabilización y el ajuste los temas que dominaban la literatura, los debates y hasta las conversaciones de los economistas. Hoy, es cada vez más frecuente la referencia a la pobreza, el costo social del ajuste, el rostro humano de la política económica, el gasto social, la salud, la educación, en fin, todos aquellos temas relativos a la calidad de vida y el desarrollo humano. A diferencia del pasado, sin embargo, este redescubrimiento de los objetivos sociales del desarrollo no olvida, sino que parte precisamente del reconocimiento de las limitaciones materiales y financieras que enfrentan las sociedades menos desarrolladas. La discusión actual busca redefinir el sentido de la política social en los tiempos del ajuste o, si se quiere, redefinir los procesos de ajuste a la luz de su verdadero objetivo: el desarrollo social.

  10. Controladores auto-ajustables para una clase de sistemas bilineales

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    Anna Patete

    2011-06-01

    Full Text Available En este trabajo, se propone un algoritmo auto-ajustable implícito basado en el criterio de varianza mínima generalizada para la estabilización de una clase de sistemas bilineales. La estabilidad del algoritmo propuesto es demostrada usando una función de Lyapunov y la estrategia de control por superficie deslizante. El algoritmo auto-ajustable propuesto es aplicado a una planta piloto térmica para evaluar su desempeño. / In this paper, a self-tuning algorithm based on the generalized minimum variance criterion is proposed for the stabilization of a class of bilinear systems. Using a Lyapunov function and the sliding mode control approach, the stability of the proposed algorithm is proven. The proposed self-tuning algorithm is applied to a simulated example to evaluate its performance.

  11. Ajustes Conversacionales para el Aprendizaje de Contenidos en L2

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    Berta de Dios

    2010-07-01

    Full Text Available Este trabajo pretende describir las interacciones conversacionales entre el alumnado en las aulas AICLE. Nos preguntamos si hay un vínculo entre las características de las interacciones y el aprendizaje de contenidos no lingüísticos y, si es así, qué tipo de ajustes fomentan dicho aprendizaje. Las aulas AICLE son los entornos ideales para estudiar el vínculo entre ajustes conversacionales y aprendizaje de contenidos porque, al no ser en la lengua materna del alumnado, se dan más ajustes conversacionales que en las clases en lengua materna.---------------------------------------------This article pursues to describe conversational adjustments among students in CLIL classes. We wonder if there is a link between the characteristics of the interactions and the learning of non-linguistic contents and, if there is, what kind of adjustments promote such learning. CLIL classes are the ideal environments to study the link between conversational adjustments and the learning of contents because, since they are not in the students’ mother tongue, conversational adjustments occur more frequently than in classes in mother tongue.

  12. Modelo de atmosfera solar ajustado às observações do raio solar em 17GHz

    Science.gov (United States)

    Selhorst, C. L.; Silva, A. V. R.; Costa, J. E. R.

    2003-08-01

    O estudo das variações do raio solar durante o ciclo de atividades do Sol e das diferenças em relação à sua distribuição angular nos fornece informações importantes sobre as mudanças na estrutura da atmosfera solar. Neste trabalho foram analisados mais de 3600 mapas do Sol em 17 GHz obtidos pelo Rádio Heliógrafo de Nobeyama (NoRH), durante 1 ciclo de atividade solar (1992-2003). O raio solar foi definido no ponto onde a temperatura de brilho do mapa era equivalente à metade da temperatura do Sol calmo (temperatura mais comum no mapa).Em relação à sua variação ao longo do ciclo solar, o estudo foi dividido em duas partes: a) ajuste de uma circunferência a pontos distribuídos ao redor do Sol todo. Este estudo mostrou uma variação correlacionada com o ciclo de atividade do Sol. b) ajuste da circunferência a pontos situados somente nas regiões polares. Neste caso os resultados mostraram que o raio polar sofre pouca variação durante o ciclo, com tendência à anticorrelação com este. Além disto, a média do raio polar, durante o período analisado, foi 1" menor que o raio medido no Sol todo. Para estudar a distribuição angular do raio solar, comparamos a média da distribuição de 10 mapas no período de mínima atividade solar com a média de 10 mapas no período de máximo, este estudo mostrou um grande aumento do raio na região equatorial no período de máxima atividade solar. As medidas do raio foram usadas como um dos parâmetros para a criação de um modelo atmosférico (além da temperatura de brilho do Sol e do abrilhantamento do limbo observado), onde mostramos que um modelo atmosférico com a região de transição situada a 3500 km fornece um raio 5" menor que as medidas observacionais. Esta incompatibilidade do modelo com os dados observacionais foi contornada com a inclusão de espículas, estas fazem com que o raio solar aumente proporcionalmente à altura que estas atingem na atmosfera solar. A anticorrelação do raio

  13. Revocatoria del mandato: experiencias, dificultades y ajustes necesarios

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    William W. Jimu00E9nez

    2001-01-01

    Full Text Available En 1994 se introdujo en Colombia la figura de la Revocatoria del Mandato a los alcaldes y gobernadores como mecanismo tendiente al fortalecimiento de la democracia local. El presente artículo realiza un análisis de los 10 casos de revocatorias realizados hasta el 2.000. Con base en datos electorales registrados, la opinión de algunos expertos y el testimonio directo de actores involucrados; se presentan las dificultades, logros y limitaciones encontrados. En general, se observa la inoperancia, poco uso, alta abstención electoral e ineficacia política de la revocatoria. Finalmente, se realizan algunas recomendaciones con miras a realizar ajustes necesarios y urgentes.

  14. Estudo comparativo de diferentes prescrições de braquetes pré-ajustados em modelos virtuais pelo Método de Elementos Finitos Comparative study of different pre-adjusted brackets prescriptions on virtual models, by Finite Elements Method

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    Murilo Fernando Neuppmann Feres

    2009-08-01

    Full Text Available OBJETIVOS: comparar os efeitos de diferentes prescrições de braquetes pré-ajustados na movimentação dentária dos dentes anterossuperiores, por meio da utilização do Método de Elementos Finitos (MEF. MÉTODOS: foi utilizado um modelo tridimensional composto por um incisivo central, um incisivo lateral e um canino, todos do hemiarco superior esquerdo. Esses elementos foram submetidos à atuação de vetores de força que simularam a ação dos pré-ajustes de angulação e torque dos braquetes das prescrições de Alexander, Andrews, Capelozza, MBT, Ricketts e Roth. Após a simulação, os dados referentes ao deslocamento espacial dos pontos incisais e apicais foram registrados de forma que o novo posicionamento admitido pelos longos eixos dentários e seus pontos constituintes fossem determinados. RESULTADOS: a maioria das prescrições se comportou similarmente em relação aos parâmetros avaliados. As diferenças significativas encontradas no estudo se referem ao incisivo lateral superior que continha o braquete com a prescrição de Ricketts, que apresentou uma menor inclinação vestibular de seu longo eixo. Além disso, o canino superior da mesma prescrição apresentou uma maior inclinação de seu longo eixo para mesial e uma maior inclinação vestibular de seu longo eixo em relação às outras. A avaliação qualitativa da movimentação do incisivo central superior indicou um maior deslocamento distal dos ápices radiculares para as prescrições cujos autores estipularam maiores valores de angulação (Andrews, Capelozza, Roth e Alexander, e um maior deslocamento vestibular da coroa para as prescrições que estipularam os maiores valores de torque para os incisivos centrais (Ricketts, MBT, Alexander e Roth.AIM: The aim of the present study was to compare the effects of different prescriptions on anterior superior tooth movement simulation through a Finite Element Method (FEM. METHODS: It was utilized a 3D model, which was

  15. Ajustes ambientais nos modelos DEA e a agricultura irrigada

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    Yony Sampaio

    2012-09-01

    Full Text Available Modelos DEA têm sido extensivamente utilizados para medir eficiência e definir políticas. O modelo original não considera o caráter dinâmico e estocástico do ambiente agrícola. Em consequência, um produtor pode tomar decisões corretas mas obter um resultado menos satisfatório que outro devido a mudanças de preço ou de produtividade, decorrentes, por exemplo, do excesso de chuva. Para corrigir este problema é proposto um modelo em dois estágios que incorpora distribuições de preço e produtividade. Resultados de eficiência de produtores da fruticultura irrigada apontaram distribuição dos escores de eficiência do DEA-ajustado mais concentrada, suavizando os efeitos da aleatoriedade característica da produção agrícola.DEA models are frequently used to measure efficiency and propose policies. The original model does not consider the dynamic and stochastic set of agricultural production. As a consequence, a producer can make the correct decisions but obtain less satisfactory results due to price or productivity changes, resulting, for example, from excessive rain. To correct this problem a two-stage model that consider price and productivity distributions is proposed. Results comparing the efficiency of irrigated agriculture producers show that the distribution of efficiency scores are more centered, reducing the stochastic effects typical of agricultural production.

  16. Benchmark para la Evaluación de Algoritmos de Auto-ajuste de Controladores PID

    OpenAIRE

    Romero Pérez, Julio Ariel; Sanchis Llopis, Roberto

    2011-01-01

    En este artículo se propone una metodología para la evaluación de algoritmos de auto-ajuste de controladores PID. Para ello se definen índices cuantitativos que permiten medir el comportamiento de los algoritmos, tanto durante la realización del experimento como en la fase de control. La metodología presentada pretende ser una herramienta que permita realizar estudios comparativos entre algoritmos de auto-ajuste.

  17. Capacidade máxima de adsorção de fósforo e constante de energia em Latossolo Bruno em razão de diferentes ajustes do modelo Langmuir

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    Clovisson Menotti Boeira de Oliveira

    2014-12-01

    Full Text Available A capacidade máxima de adsorção de fósforo (CMAP é um parâmetro bastante útil para caracterizar a capacidade de adsorção de fósforo (P do solo e, por isso, o modelo de Langmuir, que possibilita essa estimativa, é bastante difundido. Porém, se o ajuste da equação for realizado por modelos não lineares ou linearizados, ou se forem escolhidos modelos de região única ou múltiplas, nem sempre os valores estimados da CMAP e da constante de energia de ligação (k são semelhantes. O objetivo deste trabalho foi avaliar o efeito do uso de diferentes métodos de ajuste do modelo de Langmuir sobre os valores estimados de CMAP e k. Para isso, utilizouse um único solo de alta capacidade de adsorção de P, o qual foi misturado a quantidades crescentes de areia lavada, construindo-se sistemas com capacidades de sorção crescentes, mas com a fase sólida constituída da mesma mineralogia. Foi utilizado solo do horizonte B de um Latossolo Bruno com 800 g kg-1 de argila, o qual foi misturado com areia em quantidades para obterem-se solos artificiais com 0, 200, 400, 600 e 800 g kg-1 de argila. Esses solos artificiais foram incubados por 30 dias com calcário para elevar o pH(H2O até 6,0 e, após, foram secos em estufa e peneirados. Foram realizadas as isotermas de adsorção e os dados ajustados pelo modelo de Langmuir, usando os seguintes métodos: NLin - não linear com região única; L-1R - linearização com região única; L-2RG - linearização com duas regiões, ajuste gráfico; L-3RG - linearização com três regiões, ajuste gráfico; L-2RE linerização com duas regiões, ajuste estatístico. Os resultados evidenciaram que todos os métodos utilizados estimaram valores de CMAP proporcionais ao teor de argila dos solos e poderiam ser usados para caracterizar os solos. Contudo, quando utilizados ajustes com mais de uma região de adsorção, os valores da CMAP para a última região foram sensivelmente superiores

  18. Instrumento de evaluación económica para la medición de años de vida ajustados a la calidad en adultos mayores

    OpenAIRE

    Enrique Novo Rodríguez

    2013-01-01

    Se diseñó un instrumento único, del tipo análisis costo-utilidad, para medir los años de vida ajustados a la calidad en adultos mayores, que incluye satisfacción, cantidad y calidad de vida, motivado por insuficiencias en la evaluación económica del Programa Nacional de Atención Integral al Adulto Mayor. Este incluye 5 dimensiones y 3 niveles en cada una de ellas. Los resultados muestran que el instrumento diseñado determina los años de vida ajustados a la calidad.

  19. AJUSTE PSICOSOCIAL, BIENESTAR SUBJETIVO Y OCIO EN ADULTOS MAYORES JUBILADOS MEXICANOS

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    Christian Oswaldo Acosta Quiroz

    2015-01-01

    Full Text Available El objetivo de este estudio fue establecer la relación entre ajuste psicosocial en la jubilación,bienestar subjetivo, actividades de ocio y variables sociodemográficas en adultos mayores ju-bilados mexicanos. Participaron 181 adultos mayores con una edad media de 69.12 años y untiempo medio de jubilación de 11.21 años. Los resultados indican que el ajuste psicosocial enla jubilación y el bienestar subjetivo se relacionan significativamente entre sí y con las variablessociodemográficas de sexo, nivel de estudios, estatus de salud y estado civil. A su vez, se re-lacionan con la frecuencia de actividades de ocio (con diferencias entre hombres y mujeres.Estas variables deben tenerse en cuenta para fomentar un mayor ajuste psicosocial y bienestarsubjetivo en adultos mayores jubilados.

  20. Relaciones entre estilos educativos, temperamento y ajuste social en la infancia : una revisión

    OpenAIRE

    Ato Lozano, Ester; Galián Conesa, María Dolores; Huéscar Hernández, Elisa

    2007-01-01

    Este trabajo tiene como objetivo revisar teóricamente las principales variables que afectan al desarrollo social del niño. Tradicionalmente se ha abordado el estudio del ajuste social del niño desde la influencia unidireccional que ejerce el padre como agente socializador del niño. No obstante, este planteamiento generó un gran número de críticas por su excesiva rigidez, dado que otras variables parecen estar participando en el resultado final del ajuste, principalmente el temperamento. Desde...

  1. O aparelho pré-ajustado: sua evolução e suas prescrições The pre-adjusted appliance: evolution and prescriptions

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    Vicente de Sousa Brito Júnior

    2006-06-01

    Full Text Available Este trabalho revisou as prescrições de braquetes pré-ajustados existentes no mercado, abordando as variações dos valores de inclinação, angulação e rotação dentária. A revisão reporta desde a origem do conceito de uso de arcos retangulares em acessórios com secções retangulares até os atuais modelos de braquetes autoligados e outros braquetes com formatos diferenciados.This research intended to review all the available prescriptions of pre-adjusted orthodontic appliances in the market and to discuss the justification of the authors as to the prescribed angulation, inclination and rotation suggested. The review encompassed the rectangular wire application in Edgewise brackets, until the implementation of self ligation, and many other kinds of brackets with distinct shapes according to the utilized technique. It was clear the great variety of many orthodontic mechanotherapy and brackets prescriptions, demonstrating that Orthodontics is a science with many possible alternatives.

  2. EL FACTOR DE SOSTENIBILIDAD DEL SISTEMA PÚBLICO DE PENSIONES Y SU ENTRADA EN VIGOR. EL FACTOR DE EQUIDAD INTERGENERACIONAL “AJUSTADO A LA EDAD DE ACCESO A LA JUBILACIÓN”

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    Augusto Hoyo Lao

    2014-05-01

    Full Text Available La introducción del factor de sostenibilidad en el sistema de pensiones de la Seguridad Social y la elección del año base de aplicación constituyen decisiones de gran trascendencia debido a sus efectos reductores (acumulativos en el cálculo de las pensiones iniciales y en la revalorización de todas las pensiones. Este trabajo analiza los efectos de la aplicación anticipada del Factor de Equidad Intergeneracional (FEI, como propone el comité de expertos designado por el Gobierno de España, en concurrencia con la reforma paramétrica de la Ley 27/2011, cuantificando la reducción en las pensiones de jubilación que se causen en 2027 en torno al 26%.Se señala que la anticipación de la aplicación del FEI al periodo de transición de la reforma de 2011 supondría una redundancia de medidas orientadas a compensar el incremento en el número de años de percepción de la pensión debido al progresivo aumento de la esperanza de vida a la edad de jubilación. Además, técnicamente, el FEI es un factor inadecuado para tal objetivo cuando las condiciones de acceso y de cálculo de la pensión de jubilación van cambiando, como ocurre durante el periodo transitorio de la Ley 27/2011, en el que se dificultan estas condiciones para las cohortes que alcancen la edad legal de retiro. Como aportación de este trabajo se sugiere la aplicación de un nuevo FEI “ajustado a la edad de acceso a la jubilación” que, cumpliendo el objetivo de poner límite a la mayor longevidad, se adapta a distintos periodos (transitorio o plena vigencia de la reforma de 2011 y situaciones (como la anticipación o demora en el acceso a la jubilación y, además, es menos sensible al año de referencia que se elija para vincular la prestación a la evolución de la esperanza de vida. Se incluyen también propuestas de ajuste de los parámetros de cálculo de la pensión de jubilación para el periodo posterior a 2027. The introduction of sustainability factor in the

  3. Variabilidade do risco do tempo de permanência ajustado para lactentes de muito baixo peso ao nascer entre centros da Neocosur South American Network

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    Guillermo Marshall

    2012-12-01

    Full Text Available OBJETIVOS: Desenvolver um modelo de predição para o tempo de permanência hospitalar (TPH em lactentes de muito baixo peso ao nascer (MBPN e comparar esse resultado entre 20 centros de uma rede neonatal, visto que o TPH é utilizado como uma medida da qualidade da assistência em lactentes de MBPN. MÉTODOS: Utilizamos dados coletados prospectivamente de 7.599 lactentes com peso ao nascer entre 500 e 1.500 g no período entre os anos de 2001 a 2008. O modelo de regressão de Cox foi empregado para desenvolver dois modelos de predição: um modelo prévio com dados do nascimento e outro posterior, que acrescenta morbidades relevantes dos primeiros 30 dias de vida. RESULTADOS: A mediana do TPH estimado e ajustado a partir do nascimento foi de 59 dias; 28 dias depois do tempo de sobrevida de 30 dias. Houve uma alta correlação entre os modelos (r = 0,92. O TPH esperado e o TPH observado variaram bastante entre os centros, mesmo depois de correção para as morbidades relevantes após 30 dias. O TPH mediano (variação: 45-70 dias e a idade concepcional na alta hospitalar (variação: 36,4-39,9 semanas refletem uma variabilidade alta entre centros. CONCLUSÃO: Um modelo simples, com fatores apresentados no nascimento, pode predizer o TPH de um lactente de MBPN em uma rede neonatal. Observou-se uma variabilidade nos TPHs considerável entre unidades de terapia intensiva neonatal. Especulamos que os resultados sejam provenientes das diferenças entre as práticas dos centros.

  4. Implementación de un programa de ajuste de redes topográficas en entorno windows

    OpenAIRE

    Mañas Barros, Francisco Javier

    2012-01-01

    El objetivo principal de este trabajo es la implementación de un programa que permite el ajuste de redes topográficas observadas con estación total y por el método de la poligonación. Las poligonales que contenga la red a ajustar habrán sido realizadas mediante itinerarios cerrados, encuadrados y a su vez no orientados. Además este ajuste partirá de una línea de base con coordenadas UTM conocidas a priori. Para conseguir un ajuste de redes del modelo de red propuesta, se ha implementado el...

  5. Ajuste de modelos estocásticos lineares e não-lineares para a descrição do perfil longitudinal de árvores Fitting linear and nonlinear stochastic models to describe longitudinal tree profile

    Directory of Open Access Journals (Sweden)

    Leonardo Machado Pires

    2007-10-01

    Full Text Available Os modelos polinomiais são mais difundidos no meio florestal brasileiro na descrição do perfil de árvores devido à sua facilidade de ajuste e precisão. O mesmo não ocorre com os modelos não-lineares, os quais possuem maior dificuldade de ajuste. Dentre os modelos não-lineares clássicos, na descrição do perfil, podem-se citar o de Gompertz, o Logístico e o de Weibull. Portanto, este estudo visou comparar os modelos lineares e não lineares para a descrição do perfil de árvores. As medidas de comparação foram o coeficiente de determinação (R², o erro-padrão residual (s yx, o coeficiente de determinação corrigido (R²ajustado, o gráfico dos resíduos e a facilidade de ajuste. Os resultados ressaltaram que, dentre os modelos não-lineares, o que obteve melhor desempenho, de forma geral, foi o modelo Logístico, apesar de o modelo de Gompertz ser melhor em termos de erro-padrão residual. Nos modelos lineares, o polinômio proposto por Pires & Calegario foi superior aos demais. Ao comparar os modelos não-lineares com os lineares, o modelo Logístico foi melhor em razão, principalmente, do fato de o comportamento dos dados ser não-linear, à baixa correlação entre os parâmetros e à fácil interpretação deles, facilitando a convergência e o ajuste.Polynomial models are most commonly used in Brazilian forestry for taper modeling due to its straightforwardly fitting and precision. The use of nonlinear regression classic models, like Gompertz, Logistic and Weibull, is not very common in Brazil. Therefore, this study aimed to verify the best nonlinear and linear models, and among these the best model to describe the longitudinal tree profile. The comparison measures were: R², syx, R²adjusted, residual graphics and fitting convergence. The results pointed out that among the non-linear models the best behavior, in general, was given by the Logistic model, although the Gompertz model was superior compared with the Weibull

  6. Ajuste de parâmetros de transporte de solutos no solo utilizando Matlab 6.5 Adjustment of soil solute transport parameters with Matlab 6.5

    Directory of Open Access Journals (Sweden)

    Anderson L. de Souza

    2011-12-01

    Full Text Available O sucesso na utilização de modelos matemáticos no estudo do transporte de íons no solo está intimamente ligado à precisão com que os parâmetros de transporte envolvidos neste processo são estabelecidos. De maneira geral, tais parâmetros são determinados mediante a resolução de um problema de otimização não linear em que os dados experimentais, obtidos em ensaios de deslocamento miscível, são ajustados a um modelo teórico. Neste sentido, a utilização de softwares de alta performance no ajuste destes parâmetros mostra-se vantajosa, uma vez que, além da consistência e da disponibilidade de ferramentas numéricas preexistentes, possibilita a incorporação de novas rotinas de acordo com o fenômeno que se queira simular. Sendo assim, este trabalho teve como objetivo desenvolver, em ambiente MATLAB 6.5, uma rotina computacional para a otimização dos seguintes parâmetros de transporte: fator de retardamento (R e coeficiente de dispersão (D. A rotina desenvolvida foi aplicada a dados experimentais de três ensaios de deslocamento miscível do íon potássio em colunas preenchidas com um Latossolo Vermelho- -Amarelo, fase arenosa. A qualidade dos ajustes obtidos foi avaliada utilizando-se do coeficiente de exatidão. Concluiu-se que a rotina proposta apresentou ótimo desempenho, o que, além de reforçar a consistência do método numérico utilizado, indica que a rotina proposta neste trabalho pode contribuir com o avanço dos estudos teóricos da dinâmica da água e de solutos em meios porosos não saturados.The successful use of mathematical models in studies of solute transport in soil is dependent on the accuracy to which the transport parameters involved in this process can be specified. In general, these parameters are determined by using nonlinear optimization techniques to fit theoretical models to experimental data obtained in miscible displacement experiments. The use, therefore, of high-performance software to

  7. Incorporação da densidade no ajuste de dois modelos à curva de retenção de água no solo

    Directory of Open Access Journals (Sweden)

    C. A. Tormena

    2002-06-01

    Full Text Available A curva de retenção de água no solo é fundamental para o desenvolvimento de estudos relacionados com a dinâmica da água, com a modelagem de processos físicos do solo e crescimento das plantas. Normalmente, a curva de retenção é obtida por meio de medidas simultâneas do conteúdo de água (θ e do potencial mátrico da água no solo (ψ numa única amostra. Um procedimento alternativo consiste em utilizar várias amostras por ψ para descrever a curva de retenção. A utilização deste procedimento requer a incorporação dos fatores de variação existentes entre as amostras nos parâmetros das funções matemáticas utilizadas para descrever essa curva. O objetivo deste trabalho foi obter a curva de retenção, utilizando esta última sistemática, e ajustar duas diferentes funções não-lineares aos dados de θ(ψ. Amostras indeformadas (0,05 m de diâmetro e 0,05 m de altura foram obtidas num Latossolo Vermelho distroférrico cultivado com milho sob plantio direto e preparo convencional do solo. Foram retiradas 96 amostras por sistema de preparo, na profundidade de 0-0,10 m, na linha e na entrelinha da cultura. A curva de retenção foi obtida utilizando-se 12 ψ, sendo 16 amostras por ψ: oito por sistema de preparo e quatro por posição amostrada. Os modelos de Genuchten (1980 - VG e o de Hutson & Cass (1987 - HC foram ajustados aos dados. Funções relacionando os parâmetros dos modelos com as variáveis independentes preparo, posição de amostragem e densidade do solo (Ds os substituíram no ajuste dos dados. Não houve influência estatisticamente significativa dos sistemas de preparo e posição de amostragem (p > 0,05 no ajuste das funções aos dados . Com a função de VG obtiveram-se efeitos significativos da Ds no parâmetro n, o qual foi descrito por uma função quadrática da Ds. Resultado similar foi obtido com o parâmetro "a" da função de HC. A curva de retenção foi sensível às variações da Ds e o

  8. Estratégia de corrida em média e longa distância: como ocorrem os ajustes de velocidade ao longo da prova? La estratégia de la carrera del media y larga distancia: como se producen los ajustes de velocidad a lo largo de la carrera? Pacing strategy in middle and long distance running: how are velocities adjusted during the race?

    Directory of Open Access Journals (Sweden)

    Everton Crivoi do Carmo

    2012-06-01

    Full Text Available A estratégia de corrida tem sido apontada como um fator decisivo para o sucesso do atleta. Durante corridas de média e longa duração, a melhor estratégia será aquela capaz de poupar as "reservas fisiológicas", permitindo ao atleta terminar a prova no menor tempo possível. O controle da estratégia de corrida parece ser influenciado por fatores fisiológicos e psicológicos, que são ajustados constantemente durante a corrida, permitindo ao atleta determinar a intensidade do esforço. Diversas variáveis fisiológicas têm sido relacionadas aos ajustes da estratégia de corrida, no entanto, os resultados observados são controversos e foco de grandes discussões. Assim, a presente revisão tem como objetivo propiciar aos profissionais do esporte um melhor entendimento de questões como: 1 quais as melhores estratégias adotadas para determinado tipo de prova?; 2 como os ajustes da estratégia de corrida são realizados?; e 3 quais variáveis fisiológicas influenciam no controle da estratégia de corrida?La estrategia de la carrera ha sido identificada como un factor decisivo para el éxito del atleta. Durante las carreras de médio y largo plazo, la mejor estrategia es aquella que puede salvar a la "reserva fisiológica" que permite al atleta terminar la carrera en el menor tiempo posible. El control de la estrategia de carrera parece estar influenciada por algunos factores fisiológicos y psicológicos, que se ajustan com frecuencia durante la carrera, lo que permite al atleta determinar la intensidad del esfuerzo. Muchas de las variables fisiológicas se han relacionadas con los ajustes de la estrategia de carrera, sin embargo, los resultados observados son controvertidos y foco de muchos debates. Por lo tanto, esta revisión tiene como objetivo proporcionar a los profesionales del deporte una mejor comprensión de temas tales como: 1 cuáles son las mejores estrategias adoptadas para un tipo particular de prubea?; 2 cómo los ajustes

  9. Desempenho dos ajustes do Trauma and Injury Severity Score (TRISS: revisão integrativa

    Directory of Open Access Journals (Sweden)

    Cristiane de Alencar Domingues

    2015-12-01

    Full Text Available RESUMO Objetivo identificar estudos que realizaram ajustes na equação do Trauma and InjurySeverity Score (TRISS e compararam a capacidade discriminatória da equação modificada com a original. Método Revisão integrativa de pesquisas publicadas entre 1990 e 2014 nas bases de dados LILACS, MEDLINE, PubMed e SciELO utilizando-se a palavra TRISS. Resultados foram incluídos 32 estudos na revisão. Dos 67 ajustes de equações do TRISS identificados, 35 (52,2% resultaram em melhora na acurácia do índice para predizer a probabilidade de sobrevida de vítimas de trauma. Ajustes dos coeficientes do TRISS à população de estudo foram frequentes, mas nem sempre melhoraram a capacidade preditiva dos modelos analisados. A substituição de variáveis fisiológicas do Revised Trauma Score (RTS e modificações do Injury Severity Score (ISS na equação original tiveram desempenho variado. A mudança na forma de inclusão da idade na equação, assim como a inserção do gênero, comorbidades e mecanismo do trauma apresentaram tendência de melhora do desempenho do TRISS. Conclusão Diferentes propostas de ajustes no TRISS foram identificadas nesta revisão e indicaram, principalmente, fragilidades do RTS no modelo original e necessidade de alteração da forma de inclusão da idade na equação para melhora da capacidade preditiva do índice.

  10. Identificação e modelagem da autocorrelação residual no ajuste do modelo de Wood às curvas de lactação de cabras Identification and modeling of residual autocorrelation in the adjustments of Wood’s model to lactation curves of goats

    Directory of Open Access Journals (Sweden)

    Ana Lúcia Puerro de Melo

    2011-10-01

    Full Text Available Objetivou-se com este trabalho apresentar uma metodologia de identificação e modelagem da autocorrelação residual considerando ajustes individuais do modelo de Wood às lactações de cabras leiteiras e também avaliar a influência de tal modelagem na qualidade do ajuste. O modelo de Wood foi ajustado individualmente às lactações, considerando três estruturas residuais. Na primeira, assumiu-se independência dos erros (EI para todas as lactações, na segunda, assumiu-se a estrutura de erros autoregressivos de primeira ordem (AR1 para todas as lactações e, na terceira, nomeada por EI-AR1, foi utilizada a estrutura de erros AR1 somente para as lactações que apresentaram autocorrelação residual, segundo o teste de Durbin-Watson, e de EI para as demais. As três situações de ajuste foram comparadas pelos percentuais de convergência e pelas médias dos quadrados médios dos erros (QME e dos coeficientes de determinação ajustados (R²aj. As médias dos QME e dos R²aj apresentaram valores semelhantes nas três situações de estrutura residual. No entanto, o modelo com estrutura EI-AR1 apresentou maior convergência, o que consiste em uma vantagem, já que permite que um maior número de animais seja avaliado quanto à sua curva de lactação. Portanto, em função da maior convergência obtida, o ajuste do modelo de Wood com a estrutura EI-AR1 consiste na opção mais indicada para grandes conjuntos de dados.The objective of this research was to present a methodology for identification and modeling of residual autocorrelation considering individual adjustments of the Wood's model to lactation dairy goats and evaluate the influence of such modeling in the quality of adjustment. The Wood's model was adjusted individually for lactations in three different ways, the first have assumed independence of errors (IE for all lactations, the second have assumed autoregressives first order errors (AR1 for all lactations and the third, named

  11. Representación de la Enfermedad, Afrontamiento y Ajuste en los Trastornos Alimentarios

    Directory of Open Access Journals (Sweden)

    Yolanda Quiles Marcos

    2009-01-01

    Full Text Available El objetivo de esta investigación es evaluar la representación de la enfermedad en pacientes con un trastorno alimentario (TA, así como su relación con el afrontamiento y el ajuste, utilizando como marco teórico el Modelo del Sentido Común de Leventhal. Método: Participaron 98 mujeres diagnosticadas de un TA. La media de edad fue 20.8 años (dt=5.61. Para evaluar la representación de la enfermedad se administró la adaptación española para los TA del Cuestionario de Percepción de la Enfermedad Revisado (IPQ-R. Resultados: Respecto a la identidad, los síntomas más señalados fueron la "pérdida de peso" (89.8% y las "alteraciones en la menstruación" (81.6%. Consideran que su enfermedad tiene una larga duración y serias consecuencias, así como que tienen control y siguiendo un tratamiento es posible su curación. El 21% de la varianza de las estrategias evitativas fue explicado por diferentes dimensiones de la representación de la enfermedad. Se confirman los efectos directos de la representación de la enfermedad sobre el ajuste, pero no los del afrontamiento. Conclusiones: Los resultados apoyan la necesidad de intervenir sobre las creencias que tienen estas pacientes sobre su enfermedad con el fin de mejorar su ajuste psicosocial.

  12. Ajuste del Índice de Pont para mujeres y hombres

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    Paula María Nava–Salcedo

    2014-07-01

    Full Text Available La forma de arco dental de mujeres y hombres es diferente, en los hombres es amplio y en mujeres de forma parabólica. En ortodoncia existen índices y métodos para la predicción del ancho y forma del arco ideal, uno de estos índices es el de Pont que no toma en cuenta las diferencias entre sexos. Objetivos: determinar la efectividad del índice de Pont al emplearlo en hombres y mujeres, realizar el ajuste si fuera necesario a las formulas del índice de Pont para poder aplicarlo en hombres y mujeres. Materiales y métodos: investigación descriptiva, no experimental y transversal. La muestra fue de 139 modelos de estudio, 94 de pacientes femeninos y 45 de pacientes masculinos, por lo que se seleccionaron 45 modelos de pacientes femeninos de forma aleatoria para igualar las muestras. Se compararon mediante una t de Student los valores reales de la muestra de hombres con los de las mujeres y el resultado del análisis de Pont en hombres y mujeres. Se realizó el ajuste de las constantes del índice de Pont para mujeres y  hombres, se aplicó a ambas poblaciones, el resultado se  comparó con los valores reales interpremolar e intermolar en maxilar y mandíbula. Resultados: el análisis de Pont no es efectivo para utilizarse en mujeres y hombres de Nayarit, se encontraron diferencias transversales entre ambas poblaciones, los ajustes realizados para la población femenina y masculinafue efectiva para utilizase en la población de Nayarit. Conclusiones: El índice de Pont no es aplicable debido a que sobreestima los valores de la población femenina y masculinade la población de Nayarit. Los ajustes realizados fueron efectivos y se recomienda evaluarlo en otras poblaciones.

  13. Relaciones con padres e iguales como predictoras del ajuste emocional y conductual durante la adolescencia

    OpenAIRE

    Oliva Delgado, Alfredo; Parra Jiménez, Agueda; Sánchez Queija, María Inmaculada

    2002-01-01

    El objetivo de esta investigación fue estudiar el papel que juegan las relaciones con padres e iguales en el ajuste emocional y conductual de los adolescentes. Concretamentte, pretendíamos analizar tanto la contribución independiente de padres e iguales como los posibles efectos de interacción entre ambos contextos. Una muestra de 221 chicos y 292 chicas de edades comprendidas entre los 13 y los 19 años cumplimentaron un cuestionario que incluía medidas sobre las relaciones familiares, las re...

  14. Familias con un hijo con cáncer: ajuste, crianza parental y calidad de vida

    OpenAIRE

    Torrado Val, Elena

    2015-01-01

    El diagnóstico de Cáncer en un hijo es un evento traumático que afecta a toda la familia. El objetivo de este trabajo fue evaluar, describir y comparar la Calidad de Vida relacionada con la Salud Infantil, el Ajuste y Crianza Parental y explorar la relación que existe entre estas variables en familias con un hijo diagnosticado de Cáncer Infantil en tratamiento. Se evaluaron 80 sujetos pertenecientes a 20 familias; distribuidos en 4 grupos de estudio: madres (N=20), padres (N=20), hijos enf...

  15. Ajuste del Índice de Pont para mujeres y hombres

    OpenAIRE

    Paula María Nava–Salcedo; Jaime Fabián Gutiérrez–Rojo; Alma Rosa Rojas–García

    2014-01-01

    La forma de arco dental de mujeres y hombres es diferente, en los hombres es amplio y en mujeres de forma parabólica. En ortodoncia existen índices y métodos para la predicción del ancho y forma del arco ideal, uno de estos índices es el de Pont que no toma en cuenta las diferencias entre sexos. Objetivos: determinar la efectividad del índice de Pont al emplearlo en hombres y mujeres, realizar el ajuste si fuera necesario a las formulas del índice de Pont para poder aplicarlo en hombres y muj...

  16. Le village camerounais à l'heure de l'ajustement

    OpenAIRE

    Courade, Georges

    1994-01-01

    1987 : L'État camerounais se déclare en cessasion de paiement et la crise latente, est révélée au grand jour. De proche en proche et à des degrés divers, l'ensemble des secteurs économiques et des catégories sociales est touché. L'Etat est contraint de faire appel aux institutions financières internationales pour tenter de redresser la situation. Plusieurs programmes successifs d'ajustement structurel sont mis en oeuvre pour s'achever provisoirement ? sur la dévaluation de janvier 1994. Les é...

  17. Bondad de ajuste en el análisis factorial confirmatorio

    OpenAIRE

    García Cueto, Eduardo; Gallo Álvaro, Pedro; Miranda García, Rubén

    1998-01-01

    Siguiendo el método de Montecarlo se ha llevado a cabo una simulación para el estudio del comportamiento de los índices de ajuste en el Análisis Factorial Confirmatorio. Se generaron 4.500 muestras con un total de 1.890.000 de sujetos bajo 45 condiciones distintas. Los resultados obtenidos muestran la dependencia de χ2 del tamaño muestral, siendo prácticamente irrelevante el valor de las correlaciones intrafactoriales, mientras que los índices de Bentler y Bonett se ven afectados tanto por el...

  18. O ajuste gerencial e seus limites: a falha seqüencial em perspectiva comparada

    OpenAIRE

    Flávio da Cunha Rezende

    2008-01-01

    O artigo focaliza a explicação da falha seqüencial nas reformas gerenciais. Ele trata do problema dos limites do ajuste gerencial, em uma abordagem que tenta conectar teoria e dados empíricos, articulando três níveis de análise. O primeiro nível apresenta evidências comparativas da falha seqüencial das reformas nos governos nacionais a partir de um conjunto de indicadores voltados para compreender transformações no papel dos estados. O segundo nível analítico identifica, à luz da análise de u...

  19. Apport d'un outil d'optimisation globale à l'ajustement des modèles statistiques

    OpenAIRE

    Cabarbaye, André; Faure, Julien

    2009-01-01

    Les modèles paramétriques ne peuvent représenter la réalité que si leurs paramètres ont été correctement ajustés à partir de données de retour d'expérience. La méthode d'ajustement la plus utilisée est la méthode du maximum de vraisemblance qui ne peut se suffire d'une simple technique d'optimisation locale quand les optima sont multiples. C'est la raison pour laquelle les outils existants donnent parfois des résultats erronés. Aussi avons-nous tenté d'ajuster différents modèles utilisés en f...

  20. Ajustamento psicológico e perspectiva de velhice pessoal em adultos com deficiência física Ajuste psicológico e la perspectiva percibida del envejecimiento personal en adulto y adultos moyores con discapacidad física Psychological adjustment and personal aging perspective in adults and older adults with physical disability

    Directory of Open Access Journals (Sweden)

    Marineia Crosara de Resende

    2009-12-01

    Full Text Available Foram investigadas relações entre senso de ajustamento psicológico e perspectiva de velhice em adultos e idosos com deficiência física. Participaram 90 pessoas, de ambos os sexos, com idade entre 25 e 84 anos, que responderam aos instrumentos: questionários sociodemografico e sobre a deficiência física; Inventário Sheppard de Atitudes em Relação à Velhice Pessoal; Escala de Desenvolvimento Pessoal (ajustamento psicológico. Os índices de ajustamento pessoal foram de moderados a altos, mas as mulheres pontuaram mais baixo. Para toda a amostra, quanto maior o senso de ajustamento, mais positiva a perspectiva de velhice pessoal. Os com deficiência congênita e os mais ajustados psicologicamente mostraram perspectivas mais positivas de velhice pessoal. Concluiu-se que envelhecer com uma deficiência física é um processo que exige competência adaptativa e resiliência aos eventos de vida e aos desafios acarretados pela deficiência.Realizamos una investigación para analizar las relaciones entre el ajuste psicológico y la perspectiva percibida del envejecimiento personal en adulto y adultos mayores con discapacidad física. Materiales y método: 90 participantes, ambos géneros, adultos con 25 a 84 respondieron a cuestionarios contestados pidiendo la información sobre características socio demográficas y discapacidad; el inventario de Sheppard de actitudes acerca del propio envejecimiento; y una escala que determina el ajuste psicológico percibido. Resultados: Los índices del ajuste personal eran moderados y altos. Las mujeres tenían las cuentas más bajas. Había correlaciones positivas observadas entre el ajuste psicológico positivo y las actitudes positivas acerca del propio envejecimiento. Los que tenían discapacidad congénita y el ajuste psicológico más alto divulgado demostraron perspectivas más positivas del envejecimiento personal. Conclusión: El envejecer con discapacidad física es un proceso complejo que

  1. El papel de la concertación social ante la política de ajuste

    Directory of Open Access Journals (Sweden)

    Juan Raso Delgue

    2015-10-01

    Full Text Available Contenido: Introducción. Ajuste. Modos de producción y concertación. Nuevos actores y nuevas dimensiones del conflictos. Las dimensiones de la nueva concertación. Contenidos de la nueva concertación. Conclusiones

  2. La inteligencia emocional y el ajuste psicológico: un estudio transcultural

    OpenAIRE

    Fulquez Castro, Sandra Carina

    2011-01-01

    La intel·ligència emocional (IE) és una competència de l'ésser humà. Així mateix, elements psicològics com l'autoestima, l-autoconfiança, les relacions amb els iguals i les relacions amb els pares -en el cas dels adolescents- constitueixen eines que guien la salut mental i l'adaptació social de l'individu. L'estudi que es presenta demostra l'associació existent entre la IE (atenció emocional -AE- claredat emocional -CE- i reparació emocional -RE) i les variables d'ajust psicològic, així com d...

  3. Ajustement de faisceaux du SLAM revisité en utilisant un capteur RGB-D

    OpenAIRE

    Melbouci, kathia; Naudet Collette, Sylvie; Gay-Bellile, Vincent; Ait Aider, Omar; Carrier, Mathieu; Dhome, Michel

    2015-01-01

    International audience Nous présentons dans ce papier une méthode qui intègre l'information de profondeur fournie par un capteurRGB-D, pour la cartographie et la localisation simultanée ou (Simultanuous Localization And Mapping, SLAM) afind'améliorer la précision de la localisation. Nous présentons un nouvel ajustement de faisceaux local qui permet de combiner des données ayant une information de profondeur et des données visuelles dans une même fonction de coût totalement exprimée en pixe...

  4. Experiencia en el ajuste de un relé digital multifunción para protección de un motor de inducción

    OpenAIRE

    Vernieri, Julieta Z.; Barbieri, María Beatriz; Beroqui, Mario César; Arnera, Patricia L.

    2007-01-01

    En el presente trabajo se describen los pasos empleados durante00 el ajuste de un relé digital multifunción para un motor de inducción de aplicación en la industria petroquímica, de manera de compatibilizar el ajuste de la protección con las especificaciones y limitaciones del motor. Sólo se incluye el módulo de sobrecarga por la complejidad que presenta. La falta de información incluida en el manual técnico de la protección hace necesario, para su correcto ajuste, una interpretación del mode...

  5. Comparación entre varias poblaciones estándar para el ajuste por edades

    Directory of Open Access Journals (Sweden)

    Llorca Díaz Javier

    2000-01-01

    Full Text Available FUNDAMENTO: Analizar el efecto que tiene la elección de una población de referencia sobre diferentes indicadores derivados de las tasas de mortalidad ajustadas por edad. MÉTODOS: Las tasas de mortalidad por diferentes causas de muerte en España de 1971 a 1992 son ajustadas empleando cuatro poblaciones de referencia: poblaciones españolas de 1971 y 1992, población estándar europea y población estándar mundial. Los resultados obtenidos con las cuatro poblaciones se comparan empleando tres indicadores: diferencia entre las tasas de 1992 y 1971, razón entre las tasas de 1992 y 1971y cambio anual porcentual entre 1971 y 1992. RESULTADOS: En la mayor parte de las causas de muerte estudiadas incluyendo el total de causas, la cardiopatía isquémica y casi todos los tumores, la razón de tasas y el porcentaje de cambio anual son similares con independencia de cuál sea la población estándar empleada. En cambio, la diferencia de tasas es muy diferente en función de la población de referencia. En las enfermedades infecciosas y el cáncer de testículo se produce la situación contraria: la diferencia de tasas es robusta mientras que la razón de tasas varía con la población estándar. Finalmente, la mortalidad por neumonía, enfermedad de Parkinson y cáncer de encéfalo muestra cambios en los tres indicadores utilizados. CONCLUSIONES: Es necesario realizar un análisis de las tasas específicas por edad antes de proceder a su ajuste. Este análisis permite averiguar si el ajuste por edades es correcto y qué indicador (diferencia, razón o cambio porcentual será adecuado para realizar comparaciones.

  6. Teoría de las Contingencias Múltiples Dinámicamente Entrelazadas (Abriendo la caja negra del ajuste contingente

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    Lic. Jorge Washington Barrientos

    2013-12-01

    Full Text Available La teoría de las contingencias ha ocupado un rol destacado en el estudio del diseño de las estructuras organizacionales en los últimos cincuenta años. Sus contribuciones se han dirigido en distintas direcciones, una de ellas ha sido enumeración de factores de contingencia y la posterior identificación de relaciones entre estos y los elementos estructurales.Refinamientos posteriores han conceptualizado la respuesta sistémica que permite el ajuste (“fit” de la organización a los cambios en los factores de contingencia.Este trabajo se propone repasar críticamente las principales conceptualizaciones del ajuste estructural, y a la vez proponer una nueva variable interviniente en el marco de una teoría de contingencias múltiples dinámicamente entrelazadas.

  7. Ajuste al rol de género en mujeres con y sin trastornos de la conducta alimentaria

    OpenAIRE

    González Alcántara, Karla Edith; Universidad Nacional Autónoma de México; Silva, Cecilia; Universidad Nacional Autónoma de México

    2014-01-01

    Los trastornos de la conducta alimentaria podrían estar relacionados con el ajuste al rol de género de quienes los padecen, es decir, con la distancia percibida entre las características que se acepta poseer y aquellas que conforman el ideal personal. Por tal motivo, con el fin de indagar si el ajuste al rol de género guarda relación con aquéllos, se evaluaron la autopercepción y el ideal del rol de género en una muestra de 154 mujeres con edades de entre 14 y 30 años, de las cuales 49 padecí...

  8. Consumo de sustancias durante la adolescencia: Trayectorias evolutivas y consecuencias para el ajuste psicológico

    OpenAIRE

    Alfredo Oliva; Águeda Parra; Inmaculada Sánchez-Queija

    2008-01-01

    Este estudio ha perseguido dos objetivos fundamentales: encontrar diferentes trayectorias en el consumo de sustancias a lo largo de la adolescencia y analizar las consecuencias que este consumo en la adolescencia temprana y media tiene para el ajuste emocional y comportamental al final de la adolescencia. El estudio, con un diseño descriptivo longitudinal mediante cuestionarios, se llevó a cabo sobre una muestra de 101 adolescentes (63 varones y 38 mujeres) que fueron estudiado...

  9. Inteligência emocional percebida (IEP) ajuste emocional e actividade física na terceira idade

    OpenAIRE

    Maria Manuela Lima de Figueiredo Queirós

    2007-01-01

    O interesse deste estudo está centrado na forma como interage a inteligência emocional percebida (IEP) com a prática da actividade física e que peso específi co tem cada uma das variáveis estudadas sobre o ajuste emocional das pessoas nesta faixa etária e, consequentemente, na sua qualidade de vida.

  10. Elementos para el análisis de los programas de ajuste

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    Villamizar Helena

    1991-12-01

    Full Text Available

    La aplicación de las políticas generales, preconizadas por los programas de ajuste en América Latina, en la mayoría de los casos no dieron los resultados deseados. Su éxito necesariamente requería del cumplimiento de ciertos supuestos y condiciones que permitieran que las políticas de "gestión de demanda no generaran efectos negativos sobre el crecimiento en el largo plazo. Al no cumplirse algunos de 105 supuestos teóricos básicos, y al no contar los países con flujos de capitales adecuados y con un entorno externo abierto, la aplicación de estos programas se tradujo en grandes sacrificios en el crecimiento y muchas veces en la perpetuación de situaciones recesivas. Puesto que la región aun no ha encontrado una verdadera vía de solución, se hace imperioso abordar la construcción de una nueva perspectiva teórica, basada en supuestos realistas, que permita abordar los apremiantes problemas del desarrollo latinoamericano.

  11. La influencia de las diferencias entre el padre y la madre sobre el ajuste adolescente

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    Antonia Jiménez-Iglesias

    2015-01-01

    Full Text Available Este trabajo se centra en analizar cómo influyen en el consumo de sustancias (tabaco, alcohol y cannabis y el bienestar psicológico adolescente (calidad de vida relacionada con la salud y satisfacción vital las diferencias entre el padre y la madre en afecto, promoción de la autonomía, revelación, interés y conocimiento. La muestra estuvo compuesta por 10170 chicos y chicas españoles de 13 a 18 años de familias biparentales que participaron en la edición 2006 del estudio Health Behaviour in School-aged Children (HBSC. Los resultados mostraron que los adolescentes que indicaron que su padre y madre coincidían en presentar altos niveles en las dimensiones familiares analizadas consumieron menos sustancias y tuvieron mejor bienestar psicológico. Por el contrario, el ajuste de los adolescentes cuyos progenitores (padre y madre tenían bajos niveles en esas dimensiones familiares fue peor. Concretamente, la dimensión más importante para el consumo de sustancias fue el conocimiento parental y para el bienestar psicológico lo fue el afecto parental; la revelación adolescente solo fue relevante para el consumo de alcohol y la calidad de vida, mientras que la promoción parental de la autonomía lo fue para la calidad de vida.

  12. Les réinventions du social dans le Maroc “ajusté”

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    Myriam Catusse

    2012-01-01

    Full Text Available Le Maroc de l’ajustement structurel et de la libéralisation économique est le théâtre d’une prise de conscience politique de l’exacerbation des risques sociaux – et de leurs éventuelles conséquences politiques. En l’espace de peu de temps a été adopté un vaste train de lois sociales, au premier chef desquelles un nouveau code du travail en 2003, remplaçant un dispositif vétuste hérité de la période coloniale. Parallèlement, sont créées des institutions para-publiques pour organiser une prise en charge associative et privée de l’aide aux “démunis”. Cet article se propose d’examiner les logiques présidant d’une part à une activité législative directement tournée vers une amélioration de la protection des salariés protégés et d’autre part à des actions d’assistanat ad hoc encouragées tant par les pouvoirs publics que par de grandes institutions internationales. Si cette accélération des réformes sociales se fonde sur l’idée de l’échec de l’intégration par le travail, elle participe d’une redéfinition des rôles de l’État marocain et d’une transformation des configurations d’acteurs et institutions participant à la prise en charge du social, dans un processus de dépolitisation de la question sociale.

  13. Inteligencia emocional y ajuste psicosocial en la adolescencia: El papel de la percepción emocional

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    José M. Salguero

    2011-12-01

    Full Text Available La inteligencia emocional (IE, definida como la habilidad para percibir, usar, comprender y regular las emociones, se ha mostrado como una variable importante a la hora de explicar el ajuste psicosocial de las personas. Pese a ello, la mayor parte de la investigación en torno a la IE ha sido realizada con muestras de población adulta y son escasos los trabajos que, utilizando medidas de ejecución, exploren su papel en la adolescencia. El objetivo del presente estudio fue el de analizar la influencia de la percepción emocional, una de las habilidades recogidas dentro de la IE, sobre el ajuste personal y social de una muestra de adolescentes españoles. Un total de 255 alumnos completaron una tarea de ejecución diseñada para evaluar la percepción emocional en la adolescencia así como diferentes medidas de ajuste social y personal. Los resultados de los análisis de correlación y regresión mostraron cómo los adolescentes con una mayor habilidad para reconocer los estados emocionales de los demás informaron de mejores relaciones sociales con iguales y padres, menor tensión en sus relaciones sociales, así como de un mayor nivel de confianza y competencia percibida. Además, estos resultados se mantuvieron tras controlar los efectos de la edad, el sexo y la personalidad. Se discuten los resultados en el contexto de la investigación sobre la inteligencia emocional y se proponen implicaciones prácticas para el diseño de programas de prevención y tratamiento

  14. Ajuste do modelo de Schumacher e Hall e aplicação de redes neurais artificiais para estimar volume de árvores de eucalipto Adjustment of the Schumacher and Hall model and application of artificial neural networks to estimate volume of eucalypt trees

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    Mayra Luiza Marques da Silva

    2009-12-01

    Full Text Available Objetivou-se, neste trabalho, avaliar o ajuste do modelo volumétrico de Schumacher e Hall por diferentes algoritmos, bem como a aplicação de redes neurais artificiais para estimação do volume de madeira de eucalipto em função do diâmetro a 1,30 m do solo (DAP, da altura total (Ht e do clone. Foram utilizadas 21 cubagens de povoamentos de clones de eucalipto com DAP variando de 4,5 a 28,3 cm e altura total de 6,6 a 33,8 m, num total de 862 árvores. O modelo volumétrico de Schumacher e Hall foi ajustado nas formas linear e não linear, com os seguintes algoritmos: Gauss-Newton, Quasi-Newton, Levenberg-Marquardt, Simplex, Hooke-Jeeves Pattern, Rosenbrock Pattern, Simplex, Hooke-Jeeves e Rosenbrock, utilizado simultaneamente com o método Quasi-Newton e com o princípio da Máxima Verossimilhança. Diferentes arquiteturas e modelos (Multilayer Perceptron MLP e Radial Basis Function RBF de redes neurais artificiais foram testados, sendo selecionadas as redes que melhor representaram os dados. As estimativas dos volumes foram avaliadas por gráficos de volume estimado em função do volume observado e pelo teste estatístico L&O. Assim, conclui-se que o ajuste do modelo de Schumacher e Hall pode ser usado na sua forma linear, com boa representatividade e sem apresentar tendenciosidade; os algoritmos Gauss-Newton, Quasi-Newton e Levenberg-Marquardt mostraram-se eficientes para o ajuste do modelo volumétrico de Schumacher e Hall, e as redes neurais artificiais apresentaram boa adequação ao problema, sendo elas altamente recomendadas para realizar prognose da produção de florestas plantadas.This research aimed at evaluating the adjustment of Schumacher and Hall volumetric model by different algorithms and the application of artificial neural networks to estimate the volume of wood of eucalyptus according to the diameter at breast height (DBH, total height (Ht of the clone. For such, 21 scalings of stands of eucalyptus clones were used with

  15. Ajuste de estructuras metálicas coladas o fresadas sobre implantes de conexión externa e interna

    OpenAIRE

    Fernández Encinas, José Raúl

    2016-01-01

    [ES] La presente tesis doctoral se centra en el proceso de fabricación de la prótesis dental. Se considera que la estructura metálica es un elemento fundamental en la prótesis porque será la que entre en contacto directo con el implante, primero en el modelo de trabajo y posteriormente en la boca del paciente. Por ello, es necesario realizar un estudio comparativo para determinar la exactitud del ajuste entre el pilar/prótesis y el implante dental. Por esto se realizó un estudio en e...

  16. Ajuste de distribuciones diamétricas por los métodos empíricos de Johnson.

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    Lema T Álvaro

    2002-06-01

    Full Text Available Se revisa la posibilidad de uso de los métodos empíricos de Johnson para el ajuste de las distribuciones diamétricas en silvicultura, ante la falta de indicios acerca del tipo de modelo a utilizar. Se presentan las cartas gráficas necesarias para la toma de decisiones acerca del modelo y se concluye acerca de la bondad del proceso. Con ello se pretende ganar objetividad frente al uso de la presentación de histogramas únicamente ante la falta de modelos.

  17. Velocidad de ajuste del precio de las acciones por sector económico en la Bolsa Mexicana de Valores

    OpenAIRE

    Verónica Patricia Rodríguez Vázquez; Maribel Ávila Espinosa; Alejandra Torres González

    2009-01-01

    Este estudio analiza la velocidad de ajuste del precio de las acciones de la Bolsa Mexicana de Valores de enero de 1998 a diciembre de 2007; para ello, se agruparon las acciones por sectores económicos y se compararon con el Índice de Precios y Cotizaciones (IPC). Asimismo, se clasificó a los sectores económicos en fuertes y débiles, dependiendo del porcentaje de influencia dentro de la muestra del IPC. Entre los sectores fuertes se ubicó a comunicaciones y transportes, comercio, construcción...

  18. Algunas cuestiones en torno a la Traducción Audiovisual: El ajuste en el doblaje y la Gestalttheorie

    OpenAIRE

    Richart Marset, Mabel

    2011-01-01

    A partir de las investigaciones ya desarrolladas en torno a la llamada fase de «ajuste» en el proceso del doblaje, este ensayo se propone demostrar la utilidad de la Gestalttheorie para comprender y estudiar dicho fenómeno. Al mismo tiempo, y con la finalidad de apoyar dicho argumento, aporta un documento exclusivo en el que se puede comprobar el proceso de transformación entre el texto del traductor o traductora y las correcciones introducidas por el agente ajustador. Dado que el te...

  19. Ajustes Contábeis para o Cálculo do EVA: estudo sobre os procedimentos adotatos em empresas brasileiras

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    Eduardo Kazuo Kayo

    2008-06-01

    Full Text Available A geração de valor para o acionista está se tornando uma preocupação cada vez mais presente em resposta à pressão dos investidores e de conselhos de administração. Várias abordagens estão disponíveis, entre estas, uma linha de pensamento ligada ao Lucro Residual, o Valor Econômico Agregado (EVA, metodologia desenvolvida pela Stern Stewart & Co. Para cor-rigir as impropriedades percebidas na prática das demonstrações financeiras, alguns usuários da técnica do EVA ajustam os dados contábeis de acordo com os Princípios Contábeis Geralmente Aceitos, na expectativa de que tais ajustes produzam valores mais confiáveis e possam gerar ambiente propício aos comportamentos administrativos mais próximos ao ótimo esperado. A lógica e a mecânica por trás desses ajustes são tratadas ao longo do trabalho, investigando a possível correlação entre a percepção de entendimento do controller e a utilização dos métodos adotados pela organização.

  20. Consumo de sustancias durante la adolescencia:trayectorias evolutivas y consecuencias para el ajuste psicológico

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    Alfredo Oliva

    2008-01-01

    Full Text Available Este estudio ha perseguido dos objetivos fundamentales: encontrar diferentes trayectorias en el consumo de sustancias a lo largo de la adolescencia y analizar las consecuencias que este consumo en la adolescencia temprana y media tiene para el ajuste emocional y comportamental al final de la adolescencia. El estudio, con un diseño descriptivo longitudinal mediante cuestionarios, se llevó a cabo sobre una muestra de 101 adolescentes (63 varones y 38 mujeres que fueron estudiados en 3 ocasiones: a los 13, 15 y 18 años de edad. Los resultados mostraron tres grupos de adolescentes en función de las trayectorias seguidas por su consumo de sustancias: consumo bajo, consumo ascendente y experimentación precoz. La comparación entre estos tres grupos indicó un mejor ajuste psicológico en la adolescencia tardía entre los varones y mujeres del grupo de experimentadores, mientras que los problemas de conducta fueron más frecuentes entre los incluidos en el grupo de consumo ascendente. Por otra parte, los análisis de regresión señalaron que el consumo moderado de sustancias en la adolescencia temprana estaba relacionado con una autoestima más alta y con menos problemas emocionales al final de la adolescencia, pero no con más problemas externos.

  1. Historia Funcional de Morfologías Lingüísticas y su Efecto en un Ajuste Convencional

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    Nataly Yáñez Ramírez

    2011-01-01

    Full Text Available Se observó si diferentes historias funcionales construidas durante la adquisición de un conjunto de morfologías lingüísticas facilitaban un ajuste convencional. Participaron 24 estudiantes universitarios distribuidos en tres grupos, expuestos a entrenamientos construidos bajo la lógica de diferentes niveles de interacción: contextual, suplementario o selector (Ribes y López, 1985; y posteriormente se evaluó su ejecución en una tarea convencional. El entrenamiento cuyo criterio de ajuste era de tipo selector fue la que más facilitó tanto la adquisición de las morfologías lingüísticas como su uso en la tarea, efecto que pareció más evidente en los hablantes que en los escuchas. No se encontraron diferencias entre los entrenamientos contextual y suplementario. Los resultados se discuten en términos de sus implicaciones teóricas y metodológicas.

  2. Análisis de los factores de ajuste por utilización de carril en intersecciones semaforizadas de bogotá d. c.

    OpenAIRE

    Peña Lindarte, Ricardo José

    2010-01-01

    Este artículo está basado en el planteamiento metodológico desarrollado en el Manual de Capacidad de Carreteras de Estados Unidos (HCM - Highway Capacity Manual), de la Transportation Research Board (TRB), para el análisis de capacidad y niveles de servicio en intersecciones semaforizadas, asociado al factor de ajuste por utilización de carril (fLU), que corresponde a uno de los once factores de ajuste propuestos en la metodología de cálculo, en el módulo de intensidades de saturación. La est...

  3. Influencia del ajuste diádico sobre el estado de salud familiar. Percepción de las parejas de familias nucleares de Sevilla.

    OpenAIRE

    Jiménez Picón, Nerea

    2015-01-01

    Se ha determinado la influencia del ajuste diádico en el estado de salud familiar sobre una muestra de 369 familias nucleares de la provincia de Sevilla, a través de un diseño observacional, correlacional, analítico, de corte transversal. Para ello, las familias respondieron a la Escala de Autopercepción del Estado de Salud Familiar, a la Versión breve de la escala de Ajuste Diádico, a la escala de Reajuste Social y al cuestionario de Apoyo Social Percibido. Empleando los programas estadístic...

  4. Stress, anxiété et processus d’ajustement face à un examen de statistique à venir

    OpenAIRE

    Hellemans, Catherine

    2009-01-01

    Le stress perçu et l’anxiété-état face à un examen de statistique à venir, y compris son processus d’ajustement (processus de coping), sont analysés chez des étudiants de première et deuxième années de psychologie. Les analyses effectuées mettent en évidence des différences entre ces deux groupes, relatives aux niveaux de stress perçu face à l’examen de statistique à venir, ainsi que d’anxiété-état. En revanche, il n’apparaît pas de différence relative au stress dans la vie en général et à l’...

  5. Les particules illocutoires, variable d’ajustement de la traduction sous-titrante au cinéma

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    Ève Vayssière

    2010-12-01

    Full Text Available Die illokutiven Partikel fungieren als Anpassungsvariable, die beim Übersetzungsakt zur Untertitelung von Filmen entweder weggelassen werden oder erscheinen. Wenn sie einfach gelöscht werden, ergeben sich weder grammatikalische Störungen noch Informationsverlust. Das Auftauchen dieser Partikel in den deutschen Untertiteln zeigt jedoch, wie wichtig sie sind: Als Partikel der Oralität tragen sie zur Idiomatizität bei.Les particules illocutoires sont des variables d’ajustement lors de l’acte de traduction sous-titrante au cinéma, elles peuvent être supprimées sans que cela occasionne de dysfonctionnement grammatical et elles disparaissent lors de la traduction en français sans que cela occasionne une perte d’informations. Leur apparition dans les sous-titres allemands montre néanmoins leur importance : particules de l’oralité, elles sont vecteur d’« idiomaticité ».

  6. Au risque de rester "dedans" : Le double travail ajustement des usagers de drogues incarcérés

    OpenAIRE

    Fernandez, Fabrice

    2008-01-01

    L'articulation de l'expérience carcérale et de l'expérience toxicomaniaque est indissociable des types de double ajustement à la prison et à la réalité extérieure (la bifurcation, la coordination, la confrontation et la conjonction ). Selon la participation ou le refus des détenus à la logique carcérale, et leur capacité ou non à maintenir des liens avec le monde extérieur, les modes de consommation de drogues vont prendre des formes différenciées. Si l'expérience carcérale peut permettre de ...

  7. Razões da crise de implementação do Estado gerencial: desempenho versus ajuste fiscal

    OpenAIRE

    Rezende Flávio da Cunha

    2002-01-01

    O artigo tem três diferentes propósitos. Em primeiro lugar, apresenta e discute a questão da crise de implementação das políticas de reforma administrativa. Na seqüência, apresenta uma revisão seletiva das principais teorias contemporâneas que tratam dessa questão. Em seguida, sugere uma teoria adicional, que relaciona a crise de implementação das reformas ao problema dos limites de obtenção da cooperação simultânea com os objetivos programáticos de ajuste fiscal e mudança institucional. A te...

  8. Razões da crise de implementação do Estado gerencial: desempenho versus ajuste fiscal

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    Rezende Flávio da Cunha

    2002-01-01

    Full Text Available O artigo tem três diferentes propósitos. Em primeiro lugar, apresenta e discute a questão da crise de implementação das políticas de reforma administrativa. Na seqüência, apresenta uma revisão seletiva das principais teorias contemporâneas que tratam dessa questão. Em seguida, sugere uma teoria adicional, que relaciona a crise de implementação das reformas ao problema dos limites de obtenção da cooperação simultânea com os objetivos programáticos de ajuste fiscal e mudança institucional. A teoria proposta argumenta que a tensão entre maior flexibilidade burocrática, por um lado, e a demanda por maior rigor nos sistemas internos de controles burocráticos, por outro, é um poderoso mecanismo causal que tende a gerar crises sucessivas de implementação de tais políticas. Por tal razão, as reformas tendem a gerar resistência organizada à mudança, problemas de coordenação, problemas de ação coletiva e outros problemas relacionados. O artigo desenvolve o argumento de que, embora tal explicação adquira validade geral para o caso das reformas administrativas, pode ser muito mais crítico para as reformas gerenciais onde a contradição entre os objetivos de ajuste fiscal e mudança institucional é muito mais intensa.

  9. Cronograma de amostragem de alface cultivada em hidroponia para ajuste de curvas de crescimento vegetativo Sampling chronology of hydroponics lettuce plants for adjusting vegetative growth curves

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    Sidinei José Lopes

    2007-10-01

    Full Text Available O objetivo deste trabalho foi determinar o cronograma de amostragem de plantas de alface hidropônica, para ajuste de curvas de crescimento durante o período vegetativo. Foram realizados dois cultivos de alface, variedade Regina, de 8/9/2004 a 19/11/2004 (primavera/verão e 22/2/2005 a 24/5/2005 (verão/outono, em estufas de plástico do Dep. de Fitotecnia, da UFSM, Santa Maria, RS. A partir do ajuste do modelo co-seno com amostragem diária, registrada como padrão, diferentes intervalos entre as amostragens foram simulados para o ajuste do mesmo modelo. A fim de se encontrar o intervalo adequado, foi comparada a variância de falta de ajuste do modelo de amostragem diária com as variâncias de falta de ajuste dos modelos com diferentes intervalos de amostragens pelo teste F. Os cronogramas de amostragens para ajuste de curvas de crescimento de plantas de alface sob hidroponia, para experimentos de primavera/verão e verão/outono, possuem intervalos iguais a dois dias, para fitomassa seca total da planta e da folha; intervalos de quatro dias, para fitomassa de raiz; e, diariamente, para área foliar.The objective of this work was to determinate a sampling chronology to adjust lettuce hidroponic growth curves during its vegetative development. The variety Regina was grown from September 8, 2004 until November 19, 2004 (spring/summer and February 22, 2005 until May 24, 2005 (summer/fall. Plants were placed inside a plastic covered greenhouse in Santa Maria, RS, Brazil. Based on the adjusted cosine model, daily samples were taken as standard and different sampling intervals were simulated in order to better adjust the same model. To estimate de adequate sampling interval a comparison was conducted between the variance of lack of adjustment of the daily sampling with the variance of lack of adjustment of different samplings intervals using an F test. Sampling chronograms for adjusting crop growth curves of hydroponics lettuce plants for both

  10. Comparação de alguns modelos matemáticos para ajuste à curva de lactação média de um rebanho da raça Caracu Comparison of some mathematical models for the adjustment of the average milking curve of caracu breed herd

    Directory of Open Access Journals (Sweden)

    Lenira El Faro

    1999-01-01

    Full Text Available No presente estudo foi estimada a curva de lactação média de 7239 lactações de vacas da raça Caracu, com base em 299.949 controles semanais. As funções ajustadas aos dados médios da curva de lactação foram Linear Hiperbólica e Quadrática Logarítmica, como lineares, e Gama Incompleta e Polinomial Inversa, como não-lineares. Os parâmetros foram estimados por meio de processos iterativos, método de Gauss-Newton. O Coeficiente de Determinação ajustado (R²A, o Teste de Durbin-Watson (DW e os desvios (% entre as produções totais (PTL observadas e estimadas foram usados como medida da qualidade do ajuste. Os resíduos estimados, apesar de pequenos, apresentaram correlação serial positiva, pois o teste DW foi significativo para as quatro funções estudadas, indicando violação da pressuposição de independência entre estes resíduos. Os R²A foram superiores a 97% e os desvios entre as PTL observadas e estimadas, mínimos, indicando que, de acordo com estes critérios, qualquer função poderia ser usada para ajustar a curva de lactação média desse rebanho. Quanto aos componentes da curva, a melhor aproximação foi obtida pela função Polinomial Inversa, para produção inicial, tempo e produção no pico. As funções Gama Incompleta e Quadrática Logarítmica apresentaram ajustes semelhantes, porém a primeira apresentou melhor definição dos parâmetros e componentes da curva de lactação.The present study was carried out to estimate the average lactation curve of 7239 lactations of Caracu cows based on 299,949 weekly records. The functions fitted to the mean data of the lactation curve were: Linear Hyperbolic and Logarithmic Quadratic as linear and Incomplete Gamma and Inverse Polynomial function as non-linear. The parameters were estimated by iterative methods, Gauss-Newton method. The adjusted Coefficient of Determination (R²A, the Durbin-Watson test (DW and the deviations (% from actual and predicted total milk

  11. Estableciendo nexos entre Políticas de Ajuste Estructural y su impacto ambiental: una discusión metodológica

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    Rosalba Ortiz

    2011-09-01

    Full Text Available Las políticas de Ajuste Estructural han sido la base de la política económica costarricense en los últimos 10 años, por lo cual, han tenido gran incidencia en el análisis de los procesos y relaciones de cualquier sector productivo. En este contexto, los efectos ambientales de los últimos años, están decididamente influenciados por estas políticas, pues aunque, los programas de Ajuste no tienen como propósito direccionar aspectos ambientales, al modificar algunos precios relativos, pueden propiciar un cambio en el patrón de uso de un recurso, y es así como, tienen un efecto directo o indirecto sobre el ambiente

  12. Autonomía y ajuste académico : un estudio con estudiantes portugueses de primer año

    OpenAIRE

    Ana Paula Soares; M. Adelina Guisande; Almeida, Leandro S.

    2007-01-01

    Los niveles de autonomía psicológica de los alumnos desempeñan un papel importante en su ajuste a las presiones y desafíos de la vida universitaria. En este sentido, el presente estudio analiza las relaciones entre los niveles de autonomía de los estudiantes en su entrada en la Enseñanza Superior y la calidad de su ajuste académico al final del primer año. Se aplicó el Iowa Developing Autonomy Inventory (IDAI; Hood y Jackson, 1983) en el inicio del año lectivo, y el Questionário de Vivências ...

  13. Apego y Ajuste Socio Emocional: Un Estudio en Embarazadas Primigestas Attachment and Socio-Emotional Adjustment: A Study in First Pregnant Women

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    Chamarrita Farkas

    2008-05-01

    Full Text Available Este artículo se centra en el estudio del apego adulto y su relación con el ajuste socioemocional durante el primer embarazo. Se utiliza una investigación descriptiva correlacional de carácter transversal. La muestra se compone de 139 embarazadas primigestas de 19 a 40 años y nivel socio-económico medio, medio bajo y bajo. El estilo de apego fue evaluado con el Cuestionario de Apego en Adultos, CaMir, y el ajuste socioemocional con el Cuestionario de Salud Mental, OQ-45.2. Se realizan análisis descriptivos de la muestra y correlaciones entre estilos de apego y las dimensiones del Cuestionario de Ajuste Socioemocional con el Coeficiente Producto Momento de Pearson. Los resultados muestran una relación significativa entre los estilos de apego y los indicadores de ajuste.This article focuses on the study of adult attachment and its relationship with socio-emotional adjustment during the first pregnacy. A correlational descriptive study using a cross-sectional design was conducted. The sample included 139 primípara females between 19 and 40 years of age, from medium, medium-low and low socioeconomic status. The attachment style was evaluated using the Attachment Questionnaire for Adults, CaMir, and the socio-emotional adjustment with the Mental Health Questionnaire, OQ-45.2. Descriptive analyses of the sample were conducted, and the bivariate correlations between attachment styles and adjustment was estimated. The results show a significant relation between attachment styles and adjustment indexes.

  14. Acontecimientos vitales estresantes, estilo de afrontamiento y ajuste adolescente: un análisis longitudinal de los efectos de moderación

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    Rosa María Estévez Campos

    2012-01-01

    Full Text Available El objetivo principal de este estudio fue analizar la relación entre la vivencia de los acontecimientos vitales estresantes y los problemas de ajuste emocional y comportamental durante la adolescencia, prestando atención al posible efecto moderador del estilo de afrontamiento. La muestra estuvo compuesta por 90 adolescentes que fueron seguidos durante seis años, desde su adolescencia media (15-16 años hasta la adultez emergente (21-22 años. Completaron cuestionarios sobre su vivencia de acontecimientos vitales estresantes, su estilo de afrontamiento y sus problemas de ajuste tanto emocionales como comportamentales. En un diseño longitudinal se analizó la evolución de cada estilo de afrontamiento según el sexo y se efectuaron análisis de moderación de las distintas estrategias de afrontamiento en la relación entre estresores vitales y el ajuste adolescente. Los resultados mostraron que las estrategias más aproximativas (búsqueda de ayuda y resolución de problemas aumentaron con la edad, mientras que las estrategias de evitación (cognitiva y conductual disminuyeron, aunque sólo algunas trayectorias fueron estadísticamente significativas. Respecto al sexo, las chicas utilizaron con mayor frecuencia estrategias de búsqueda de ayuda. Por otro lado, los análisis de moderación revelaron que solamente los estilos de afrontamiento de evitación moderaron la relación entre la presencia de estresores y el ajuste, aunque el efecto moderador fue diferente en función del tipo de estrategia de evitación empleada. Estos resultados contribuyen a esclarecer el posible efecto de las estrategias de evitación en la adaptación del adolescente a los acontecimientos vitales estresantes y la importancia de seguir profundizando en su estudio.

  15. Velocidad de ajuste del precio de las acciones por sector económico en la Bolsa Mexicana de Valores

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    Verónica Patricia Rodríguez Vázquez

    2009-01-01

    Full Text Available Este estudio analiza la velocidad de ajuste del precio de las acciones de la Bolsa Mexicana de Valores de enero de 1998 a diciembre de 2007; para ello, se agruparon las acciones por sectores económicos y se compararon con el Índice de Precios y Cotizaciones (IPC. Asimismo, se clasificó a los sectores económicos en fuertes y débiles, dependiendo del porcentaje de influencia dentro de la muestra del IPC. Entre los sectores fuertes se ubicó a comunicaciones y transportes, comercio, construcción e industria extractiva; mientras que en los débiles a transformación, servicios y varios. El modelo de regresión utilizado fue el propuesto por Marshall y Walker (2002, con el que se buscó comprobar que los sectores fuertes ajustaban más rápidamente sus precios que los sectores débiles con respecto a la rentabilidad del mercado. Se encontró que existe evidencia de que los retornos de los sectores fuertes se adelantan a los retornos de los sectores débiles, principalmente porque los primeros ajustan más rápidamente sus precios a los movimientos del mercado.

  16. La norma L1 como alternativa a la norma L2 en el ajuste de la regresión

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    Carlos N. Bouza

    2002-01-01

    Full Text Available En este trabajo analizamos el desarrollo y los conceptos de las normas L1 y L2 y se comparan con algunos ejemplos. Por una parte la norma L1 es óptima bajo los supuestos de que los errores tienen la distribución de Laplace. Esta fue propuesta mucho antes que el MC, pero las facilidades de cómputo de éstos últimos le dieron primacía. Actualmente va adquiriendo gran importancia para las aplicaciones económicas, dado que en general los problemas de finanzas y de series temporales incumplen con las hipótesis usadas en el teorema de Gauss-Markoff. El uso de la norma L2, es el método de universal aceptación en el ajuste de la regresión. Sin embargo su optimalidad solo es válida bajo una serie de supuestos que no se cumplen en general (Teorema de Gaus- Markoff. Por lo tanto, norma L1 aparece como una alternativa mejor que la L2 en muchas aplicaciones dada su robustez ante las observaciones atípicas.

  17. P ET CO2 e SpO2 permitem ajuste ventilatório adequado em pacientes obesos mórbidos P ET CO2 y SpO2 permiten ajuste de ventilación adecuada en pacientes obesos mórbidos P ET CO2 and SpO2 allow adequate ventilatory adjustment in morbidly obese patients

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    Fábio Ely Martins Benseñor

    2004-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Apesar das diversas propostas ventilatórias para anestesia em pacientes obesos mórbidos, um consenso não foi estabelecido. Este estudo avaliou o ajuste ventilatório nestes pacientes durante anestesia baseado na oximetria e capnografia. MÉTODO: O consentimento prévio foi obtido da Comissão de Ética e dos pacientes. Excluíram-se tabagistas e portadores de doença cardíaca ou pulmonar. Foram estudados 11 pacientes com índice de massa corpórea (IMC de 59,2 ± 8,3 submetidos à gastroplastia sob anestesia geral (Grupo O. Oito não-obesos (IMC 20,2 ± 3,9 submetidos à gastrectomia formaram o grupo controle (NO. Ajustou-se a ventilação visando dióxido de carbono expiratório final (P ET CO2 menor que 40 mmHg e saturação periférica de oxigênio (SpO2 maior que 95%. Não se utilizou PEEP. Através de monitor respiratório CO2SMO Plus, mediu-se espaços mortos fisiológico, alveolar e de vias aéreas (VD phy, VD alv e VD aw e o volume corrente alveolar (VT alv. Amostras de sangue arterial e venoso central permitiram calcular PaO2/FIO2 e VD phy/VT. Os dados foram comparados e analisados por ANOVA (p JUSTIFICATIVA Y OBJETIVOS: A pesar de las diversas propuestas de ventilación para anestesia en pacientes obesos mórbidos, un consenso no fue establecido. Este estudio evaluó el ajuste de ventilación en estos pacientes durante anestesia fundamentado en la oximetria y capnografia. MÉTODO: El consentimiento previo fue obtenido de la Comisión de Ética y de los pacientes. Fueron excluidos fumantes y portadores de enfermedad cardíaca o pulmonar. Fueron estudiados once pacientes con índice de masa corpórea (IMC de 59,2 ± 8,3 sometidos a gastroplastia bajo anestesia general (Grupo O. Ocho no obesos (IMC 20,2 ± 3,9 sometidos a gastrectomia formaron el grupo control (NO. Se ajustó la ventilación visando el dióxido de carbono expiratorio final (P ET CO2 menor que 40 mmHg y saturación periférica de oxígeno (Sp

  18. Los Programas de Desarrollo Rural en la Argentina (en el contexto del ajuste macroeconómico neoliberal

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    Mabel Manzanal

    2000-09-01

    Full Text Available Este trabajo expone las estrategias de los principales programas de desarrollo rural en la Argentina, y sus alcances y posibilidades en el contexto del ajuste macroeconómico neoliberal. Discute si se están dando, o no, los cursos de acción adecuados, y si es viable la asistencia a los pobres rurales, promovida por los organismos internacionales de financiamiento, frente al impacto negativo de las políticas neoliberales sobre los pequeños y medianos productores agropecuarios.El desarrollo rural se inicia en la Argentina junto con la recuperación democrática de la década del 80, pero las primeras acciones recién comienzan a ejecutarse a principios de los 90. Desde entonces se sucedieron y se superpusieron diferentes programas, que son el objeto de este artículoThis paper discusses the strategies of Argentina’s main rural development programs, and their accomplishments and possibilities in the context of neoliberal macroeconomic adjustment. It analyzes whether the actions being carried out are suitable and whether assistance to the rural poor (promoted by international financing organizations is feasible in the face of the neoliberal policies’ negative impact on small and intermediate farmers and ranchers. Although rural development programs began in Argentina with the restoration of democracy in the 1980s, the first significant actions were not taken until the 1990s. The different programs that have followed, often overlapping, are the object of our study

  19. La industria manufacturera en Centroamérica: Perspectivas del Ajuste a la nueva política comercial regional

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    Fernando RUEDA-JUNQUERA

    2009-11-01

    Full Text Available RESUMEN: La nueva política comercial del Mercado Común Centroamericano está dando lugar a cambios en los flujos comerciales, que inducirán un ajuste inter-/intraindustrial en el sector manufacturero regional. Este artículo presenta y analiza los principales resultados de un estudio empírico que evaluó el impacto del nuevo programa de integración regional en el patrón de especialización y comercio de manufacturas de cada país miembro. El enfoque empírico empleado conllevó la construcción de hojas de balance que integraron en una base comparable los datos de producción y comercio para el sector manufacturero de cada país. Asimismo, se obtuvieron dos grupos de ratios que midieron respectivamente, la importancia relativa de los mercados regional y mundial para los subsectores manufactureros de cada país, y el potencial de éstos para una especialización inter-/intraindustrial en los dos mercados.ABSTRACT: The new trade policy in the Central American Common Market is given rise to changes in trade flows that will induce an inter-/intraindustry adjustment in the regional manufacturing sector. This article presents and analyses the main results of an empirical study which assessed the impact of the new integration scheme on each member country's pattern of trade and specialisation in manufactures. The empirical approach used in the study involved the construction of balance sheets integrating production and trade data on a comparable basis for each country's manufacturing sector. Likewise, two groups of ratios were obtained. They measured respectively, the relative importance of the regional and world market for the manufacturing subsectors of each country and the subsectoral potential for an inter-/intraindustry specialisation in the two markets.

  20. EL AJUSTE EN LA INVESTIGACIÓN SOBRE CONFIGURACIONES ESTRATÉGICAS Y DESEMPEÑO ORGANIZA TIVO: UNA RESEÑA /

    OpenAIRE

    Roca Puig, V.; Bou Llusar, J C.

    2004-01-01

    Este trabajo revisa la literatura sobre las configuraciones estratégicas, identificando tres diferentes aproximaciones a la formación de las configuraciones -los grupos estratégicos, los tipos estratégicos reales y los tipos estratégicos ideales-, Se describen sus características distintivas, el método empleado habitualmente para explicar su efecto sobre el desempeño organizativo y sus limitaciones. De especial relevancia es la ausencia del ajuste en la delimitación del concepto de configurac...

  1. Predictores del ajuste psicosocial en divorciados de Monterrey, México: un análisis de género

    OpenAIRE

    Rogelio Rodríguez Hernández; Manuel Ribeiro Ferreira

    2013-01-01

    Las tasas de divorcio han crecido en México sostenidamente en las últimas décadas. Sin embargo, la investigación respectiva es escasa, por lo que se conoce poco la experiencia del divorcio en este país. Por ello, el objetivo de este estudio es explorar los factores que predicen el ajuste psicosocial en una muestra de adultos divorciados y en proceso de divorcio en Monterrey, México. Específicamente, se pretende conocer las diferencias de género en las variables que facilitan la adaptación a l...

  2. Aplicación del método de mínimos cuadrados al ajuste de curvas granulométricas de áridos

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    Olaya, Manuel

    1978-06-01

    Full Text Available A partir de la lectura del artículo original reseñado en la llamada (1, en el Departamento de Materiales de Construcción del I.E.T.c.c, se han comprobado algunos ajustes granuiométricos de áridos obtenidos por otros métodos clásicos con los resultados que se obtienen aplicando el presente método. La buena correspondencia entre unos y otros ha sido el motivo que ha impulsado a darlo mayor difusión.

  3. Comparación entre factores de ajuste multiplicativos y aditivos para producción por lactancia en un hato holstein

    OpenAIRE

    Arboleda Zapata Elkin Mauricio; Valencia Restrepo Cesar Tulio; Montoya Serna Camilo

    2012-01-01

    La presente investigación se efectuó a partir de 558 registros de lactancia tomados del hato Holstein Paysandú el cual está situado en el corregimiento Santa Elena de Medellín en una zona ecológica de bosque húmedo montano bajo (bh-MB) y pertenece a la Facultad de Ciencias Agropecuarias de la Universidad Nacional de Colombia, Sede Medellín. El objetivo propuesto fué determinar las ventajas comparativas entre factores de ajuste multiplicativos y aditivos para producción por lactancia. Pa...

  4. Acontecimientos vitales estresantes, estilo de afrontamiento y ajuste adolescente: un análisis longitudinal de los efectos de moderación

    OpenAIRE

    Rosa María Estévez Campos; Alfredo Oliva Delgado; Águeda Parra Jiménez

    2012-01-01

    El objetivo principal de este estudio fue analizar la relación entre la vivencia de los acontecimientos vitales estresantes y los problemas de ajuste emocional y comportamental durante la adolescencia, prestando atención al posible efecto moderador del estilo de afrontamiento. La muestra estuvo compuesta por 90 adolescentes que fueron seguidos durante seis años, desde su adolescencia media (15-16 años) hasta la adultez emergente (21-22 años). Completaron cuestionarios sobre su vivencia de aco...

  5. Modelo experimental de bandagem ajustável do tronco pulmonar para preparo rápido do ventrículo

    OpenAIRE

    DIAS Carlos A.; Assad, Renato S.; CANEO Luiz F.; ABDUCH Maria Cristina D.; Aiello, Vera D.; DIAS Altamiro Ribeiro; Miguel BARBERO-MARCIAL

    2000-01-01

    OBJETIVO: Um dispositivo de bandagem do tronco pulmonar (TP) com ajuste percutâneo foi desenvolvido com o objetivo de induzir a hipertrofia rápida do ventrículo subpulmonar. MATERIAL E MÉTODOS: Consiste de um manguito de silicone insuflável percutaneamente, através de um botão de silicone auto-selante. Os corações de 7 cabritos jovens (peso médio: 8,7 kg) foram submetidos à sobrecarga sistólica imposta pelo dispositivo e avaliados sob os aspectos hemodinâmicos, ecocardiográficos e morfológico...

  6. Preparo do ventrículo subpulmonar através de dois diferentes modelos ajustáveis de bandagem do tronco pulmonar: estudo experimental

    OpenAIRE

    Luiz Fernando CANÊO; DIAS Carlos A.; ASSAD Renato Sammy; Maria Cristina Donadio ABDUCH; Aiello, Vera Demarchi; Moreira, Luiz Felipe Pinho; LOURENÇO FILHO Domingos D.; Noedir A. G Stolf

    2001-01-01

    Dois modelos de dispositivos ajustáveis foram implantados em cabritos jovens, com o objetivo de avaliar suas capacidades de bandagem do tronco pulmonar (TP) e eficiência no treinamento do ventrículo subpulmonar. Foram utilizados 3 grupos de 7 animais, submetidos ao implante de cateter balão (grupo I), implante de dispositivo de bandagem externa (grupo II) e para obtenção dos pesos dos ventrículos direito (VD), esquerdo (VE) e septo interventricular em condições normais (grupo controle). Os an...

  7. Volatilidad, deuda externa y riesgo fiscal: simulación de los efectos de las sacudidas sobre el ajuste fiscal de 13 países latinoamericanos

    OpenAIRE

    Kenneth Kletzer

    1997-01-01

    (Disponible en idioma inglés únicamente) En este trabajo se analiza de qué manera la combinación de endeudamiento y sacudidas exógenas inducen la inestabilidad de los países latinoamericanos. Se presenta una técnica para simular los efectos de las sacudidas en los costos del endeudamiento externo y la respuesta de las políticas fiscales en el ajuste a dichas sacudidas, y la misma se aplica a 13 países latinoamericanos endeudados.

  8. Preparação de cerâmicos de YSZ tricamada porosa/densa/porosa com porosidade ajustável

    OpenAIRE

    Almeida, Bruno Araújo de

    2009-01-01

    O trabalho realizado tem como principal objectivo obter cerâmicos tricamada porosa/densa/porosa de YSZ (sigla inglesa para Yttria-Stabilized Zirconia), com micro e macroporosidade de geometria ajustável, recorrendo a réplicas de materiais orgânicos fibrosos e particulados, bem como obter células electroquímicas de alta temperatura por inflitração de soluções de precursores adequados nas camadas porosas de YSZ. Recorreu-se a várias técnicas de caracterização tais como o cálculo de densidade...

  9. Ajuste al retiro laboral en función del tipo de retiro y su voluntariedad desde una perspectiva de género

    OpenAIRE

    Kristina Potocnik; Nuria Tordera; José María Peiró

    2008-01-01

    En el presente trabajo examinamos el ajuste al retiro laboral, examinando la satisfacción con la jubilación y bienestar psicológico en una muestra de 260 prejubilados y jubilados. Se consideraron tres factores: el tipo de retiro (prejubilación o jubilación), la percepción de la medida en que la salida del rol laboral fue voluntaria (voluntariedad) y el género. Los resultados muestran que las personas que se jubilaron y que lo hicieron voluntariamente perciben mayores niveles de satisfacción c...

  10. Afectividad inducida e impacto en la creatividad, crecimiento personal después del cambio y ajuste percibido al narrar una experiencia emocional intensa

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    Silvia da Costa

    2015-05-01

    Full Text Available Se examinan en un estudio experimental los efectos de la inducción de afectividad positiva en la creatividad y la importancia de las emociones como variables mediadoras. Se indujo alta y baja afectividad positiva pidiendo a las personas participantes que redactaran tres poemas haikus sobre dos estímulos de connotación positiva, alta (N = 28 y baja (N = 28. Las personas escribieron sobre su experiencia de enamoramiento más intenso y contestaron una escala sobre las emociones sentidas al redactar el texto, una medida de crecimiento personal y una tercera referida a la obtención de metas adaptativas después del episodio. En la condición de alta afectividad positiva se informó de más emociones positivas y menos negativas al narrar la experiencia, un mayor crecimiento personal y un mayor ajuste. Jueces independientes evaluaron como más originales el último poema y la narración de la experiencia en la condición de alta afectividad positiva. Un análisis mediacional mostró que las emociones positivas explicaban la influencia de la manipulación sobre el crecimiento personal y el ajuste percibido.

  11. Ajuste fiscal nos estados: uma análise do período 1998-2006 Fiscal adjustment in brazilian states

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    Sérgio Wulff Gobetti

    2010-01-01

    Full Text Available O objetivo deste artigo é analisar a forma de enquadramento dos estados ao Programa de Ajuste Fiscal (PAF e à Lei de Responsabilidade Fiscal (LRF, destacando seus impactos nas escolhas de alocação dos recursos públicos e na taxa de investimento. Os resultados obtidos após minucioso trabalho de depuração das bases de dados confirmam a melhoria da situação financeira de estados no período posterior à LRF, mas sugerem que existe um trade-off entre os indicadores fiscais, de um lado, e os investimentos e gastos em infraestrutura, de outro, exigindo uma reflexão sobre a qualidade e sustentabilidade do ajuste fiscal. Os dados orçamentários analisados também apontam evidências de contabilidade criativa.The objective of this article is to offer an analysis of the accommodation by Brazilian states with Fiscal Adjustment Program and with Fiscal Responsibility Act (FRA, showing their impacts on the choices of public resources allocation and on the investment rate. The results obtained after detailed work of data depuration confirm the improvement of financial situation of the states in the period post FRA, but also suggest the existence of a trade-off between fiscal indicators and infrastructure investment, demanding a reflection about the quality and the sustainability of the fiscal adjustment. The budget data analyzed also indicate evidences of creative accountability.

  12. UNA APROXIMACIÓN TEÓRICA A LA VALORACIÓN DEL DOBLE AJUSTE EN EL DISEÑO DE LA ESTRATEGIA DE RECURSOS HUMANOS

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    García Carbonell, Natalia

    2013-05-01

    Full Text Available Tradicionalmente la literatura ha considerado la necesidad del doble ajuste, vertical y horizontal, de la estrategia de recursos humanos en las organizaciones. Su importancia estratégica ha sido demostrada en buena parte de los estudios empíricos planteados. Sin embargo, la complejidad de este proceso requiere de un análisis más profundo que permita identificar los elementos que lo hacen posible. En el presente trabajo, partiendo de la revisión de la literatura de las perspectivas de investigación en dirección estratégica de recursos humanos y del concepto «fortaleza del sistema de recursos humanos» propuesto por Bowen y Ostroff (2004, discutimos los 3 factores que integran dicho concepto y su relación con el ajuste del sistema. Como consecuencia de ello, definimos 3 proposiciones teóricas que explican la vinculación entre ambas dimensiones y la fortaleza del sistema.

  13. Influencia de los cementos y de los diseños protésicos en el ajuste interno de estructuras de zirconia confeccionadas mediante tecnología Cad-Cam para prótesis fija

    OpenAIRE

    Sánchez Monescillo, Andrés

    2015-01-01

    1. INTRODUCCIÓN Y JUSTIFICACIÓN Aún quedan gran cantidad de elementos y variables que pueden influir en el ajuste interno de las restauraciones y cuyo desconocimiento obliga a seguir investigando. Este estudio permite conocer si existe una influencia real en el ajuste interno de estructuras de zirconia fabricadas mediante tecnología CAD-CAM en función del tipo de cemento utilizado y del tipo de convergencia oclusal de la preparación realizada. 2. OBJETIVOS - Evaluar la influencia de disti...

  14. El ajuste estructural neoliberal en el sector agrario latinoamericano en la era de la globalización

    Directory of Open Access Journals (Sweden)

    Francisco García Pascual

    2003-10-01

    productividad,  balanza comercial, precios implícitos en la producción y en la exportación o nivel de ingresos de  los agricultores – podemos comprobar fehacientemente que la brecha que ha separado históricamente a la agricultura latinoamericana de  los sectores agrarios de los Estados Unidos o de la  Unión Europea es cada vez mayor. Es más, los  grandes problemas que atenazaban al mundo  agrario en América Latina a principios de los  ochenta (baja productividad, distribución desigual  de los recursos productivos, exclusión social, desequilibrios territoriales, amén de la dependencia tecnológica y de la dependencia financiera del  sector siguen siendo la realidad mayoritaria  después de dos décadas de ajuste estructural.

  15. Abuso infantil y ajuste psicológico en la edad adulta: Aportaciones del estudio con pacientes con y sin psicopatología alimentaria

    OpenAIRE

    Vilanova i Salichs, Sílvia

    2016-01-01

    El presente estudio tiene como objetivo examinar la relación entre el abuso infantil [sexual (ASI) y físico (AFI)] y el ajuste psicológico en la edad adulta: sintomatología alimentaria, insatisfacción corporal, psicopatología general, autoestima y personalidad. La muestra se compone de 796 mujeres jóvenes adultas de entre 18,05 y 30,98 años (M = 22,37 años; DE = 3,32) y está dividida en tres grupos en función de la condición diagnóstica: a) grupo comunitario de estudiantes universitarias de d...

  16. P ET CO2 e SpO2 permitem ajuste ventilatório adequado em pacientes obesos mórbidos P ET CO2 y SpO2 permiten ajuste de ventilación adecuada en pacientes obesos mórbidos P ET CO2 and SpO2 allow adequate ventilatory adjustment in morbidly obese patients

    OpenAIRE

    Fábio Ely Martins Benseñor; José Otávio Costa Auler Júnior

    2004-01-01

    JUSTIFICATIVA E OBJETIVOS: Apesar das diversas propostas ventilatórias para anestesia em pacientes obesos mórbidos, um consenso não foi estabelecido. Este estudo avaliou o ajuste ventilatório nestes pacientes durante anestesia baseado na oximetria e capnografia. MÉTODO: O consentimento prévio foi obtido da Comissão de Ética e dos pacientes. Excluíram-se tabagistas e portadores de doença cardíaca ou pulmonar. Foram estudados 11 pacientes com índice de massa corpórea (IMC) de 59,2 ± 8,3 submeti...

  17. Ajuste rápido de dosis de tapentadol en el tratamiento del dolor mal controlado Fast titration of tapentadol for the treatment of badly controlled pain

    Directory of Open Access Journals (Sweden)

    M. J. Sánchez del Águila

    2012-02-01

    Full Text Available Introducción: el tapentadol es un nuevo fármaco de acción dual MOR/NRI, que actúa a nivel central, efectivo en el tratamiento del dolor moderado e intenso, que presenta un perfil de tolerabilidad mas favorable que otros opiáceos. Esto podría permitir una titulación rápida que permita un control precoz del dolor. Material y métodos: presentamos dos casos clínicos en los que se realiza una titulación rápida de la dosis de tapentadol en pacientes hospitalizados con dolor mal controlado. Este ajuste rápido, permitió controlar el dolor, en ausencia de efectos secundarios, acortando el tiempo de estancia hospitalaria de estos pacientes. Conclusiones: el perfil favorable de efectos secundarios mostrado por el tapentadol, permite un ajuste rápido de la dosis, que consigue un control eficaz del dolor en un menor lapso de tiempo.Background: tapentadol is a new drug with a centrally acting, dual action mechanism on MOR/NRI. It is effective on moderate to severe pain and shows a favourable side effects profile in comparison to other major opiates. This could allow a fast dose titration to achieve an earlier pain control. Material and methods: we present two cases on which we have performed a fast dose titration in hospitalised patients with bad pain control. This fast titration allowed an early control of the pain, in absence of side effects, achieving a shortening in their hospital stay. Conclusions: the favourable side effects profile of tapentadol, allows a fast dose titration, achieving an efficacious pain control in a shorter time lapse.

  18. Ajuste al retiro laboral en función del tipo de retiro y su voluntariedad desde una perspectiva de género

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    Kristina Potocnik

    2008-01-01

    Full Text Available En el presente trabajo examinamos el ajuste al retiro laboral, examinando la satisfacción con la jubilación y bienestar psicológico en una muestra de 260 prejubilados y jubilados. Se consideraron tres factores: el tipo de retiro (prejubilación o jubilación, la percepción de la medida en que la salida del rol laboral fue voluntaria (voluntariedad y el género. Los resultados muestran que las personas que se jubilaron y que lo hicieron voluntariamente perciben mayores niveles de satisfacción con la jubilación y bienestar psicológico en comparación con los que se prejubilaron y aquellos que lo hicieron obligatoriamente, respectivamente. Además se puso de manifiesto la interacción entre las variables consideradas en sus efectos sobre la satisfacción y el bienestar. En esta línea, entre los obligatoriamente prejubilados, las mujeres experimentan menor nivel de satisfacción con la jubilación que los hombres. Sin embargo, entre los obligatoriamente jubilados, son los hombres los que experimentan menor nivel de satisfacción con la jubilación. En relación a dichos resultados, el presente trabajo subraya la importancia de estudiar e intervenir sobre la mejora del ajuste en la experiencia del retiro laboral atendiendo tanto a las características de género como a las del proceso de transición (jubilación-prejubilación, voluntariedad-obligatoriedad.

  19. HISTORIA FUNCIONAL DE MORFOLOGÍAS LINGÜÍSTICAS Y SU EFECTO EN UN AJUSTE CONVENCIONAL/ FUNCTIONAL HISTORY OF LINGUISTIC MORPHOLOGIES AND THEIR EFFECT ON A CONVENTIONAL ADJUSTMENT/ HISTÓRIA FUNCIONAL DE MORFOLOGIAS LINGÜÍSTICAS E SEU EFEITO EM UM AJUSTE CONVENCIONAL

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    Nataly Yáñez Ramírez

    2011-12-01

    Full Text Available Se observó si diferentes historias funcionales construidas durante la adquisición de un conjunto de morfologías lingüísticas facilitaban un ajuste convencional. Participaron 24 estudiantes universitarios distribuidos en tres grupos, expuestos a entrenamientos construidos bajo la lógica de diferentes niveles de interacción: contextual, suplementario o selector (Ribes y López, 1985; y posteriormente se evaluó su ejecución en una tarea convencional. El entrenamiento cuyo criterio de ajuste era de tipo selector fue la que más facilitó tanto la adquisición de las morfologías lingüísticas como su uso en la tarea, efecto que pareció más evidente en los hablantes que en los escuchas. No se encontraron diferencias entre los entrenamientos contextual y suplementario. Los resultados se discuten en términos de sus implicaciones teóricas y metodológicas.

  20. Modelização da concentração de um fármaco em diferentes compartimentos fisiológicos: ajuste de parâmetros na ingestão e injecção de um fármaco

    OpenAIRE

    Antonio, Amilcar L.; Sanchez Léon, Guillermo

    2005-01-01

    A análise de dados em farmacocinética envolve um ajuste de dados experimentais a um modelo de forma a permitir algumas previsões acerca do sistema que está sob investigação. A escolha de um ajuste adequado aos dados experimentais é importante se se pretende uma boa modelização. Por vezes basta uma simples regressão linear, mas na maioria dos casos justifica-se a utilização de ajustes não lineares e toda a análise estatística associada.

  1. Linear study and bundle adjustment data fusion; Application to vision localization; Recherche lineaire et fusion de donnees par ajustement de faisceaux; Application a la localisation par vision

    Energy Technology Data Exchange (ETDEWEB)

    Michot, J.

    2010-12-09

    integrate this additional information directly into an extended bundle adjustment, by adding a constraint term in the weighted cost function. We evaluate three methods (based on machine learning or regularization) that dynamically select the weight associated to the constraint and show that these methods can be used in a real time multi-sensor SLAM, and validate them with different types of constraint on the orientation or on the scale. Experiments conducted on real video sequences show that this technique of constrained bundle adjustment reduces the drifts observed with the classical vision algorithms and improves the global accuracy of the positioning system. (author) [French] Les travaux presentes dans ce manuscrit concernent le domaine de la localisation et la reconstruction 3D par vision artificielle. Dans ce contexte, la trajectoire d'une camera et la structure 3D de la scene filmee sont initialement estimees par des algorithmes lineaires puis optimisees par un algorithme non-lineaire, l'ajustement de faisceaux. Cette these presente tout d'abord une technique de recherche de l'amplitude de deplacement (recherche lineaire), ou line search pour les algorithmes de minimisation iterative. La technique proposee est non iterative et peut etre rapidement implantee dans un ajustement de faisceaux traditionnel. Cette technique appelee recherche lineaire algebrique globale (G-ALS), ainsi que sa variante a deux dimensions (Two way-ALS), accelerent la convergence de l'algorithme d'ajustement de faisceaux. L'approximation de l'erreur de reprojection par une distance algebrique rend possible le calcul analytique d'une amplitude de deplacement efficace (ou de deux pour la variante Two way-ALS), par la resolution d'un polynome de degre 3 (G-ALS) ou 5 (Two way-ALS). Nos experimentations sur des donnees simulees et reelles montrent que cette amplitude, optimale en distance algebrique, est performante en distance euclidienne, et permet

  2. Ajuste de modelos de platô de resposta via regressão isotônica Response plateau models fitting via isotonic regression

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    Renata Pires Gonçalves

    2012-02-01

    Full Text Available Dentro do contexto nutricional, a suplementação de microminerais em rações para aves frequentemente é feita em quantidades superiores às exigidas na tentativa de assegurar o bom desempenho dos animais. Os experimentos do tipo dose resposta são muito comuns na determinação de níveis ótimos dos nutrientes na ração e contemplam a utilização de modelos de regressão para atingir tal objetivo. Porém, na análise de regressão usual, geralmente, não se usa uma informação a priori sobre uma possível relação de ordem na variável resposta. A regressão isotônica é um método de estimação por mínimos quadrados que gera estimativas que satisfazem a mesma ordenação dos dados. Na teoria da regressão isotônica, essa informação é utilizada de forma essencial e espera-se que a eficiência do ajuste seja aumentada quando se faz uso dela. Diante do exposto, o presente trabalho tem como objetivo utilizar uma metodologia de regressão isotônica, como uma forma alternativa para analisar dados de deposição de zinco (Zn na tíbia de aves machos da linhagem Hubbard. No estudo, foram considerados os modelos de platô de resposta polinomial quadrático e não linear exponencial. Além desses modelos, também foi proposto o ajuste de um modelo logarítmico para os dados e a eficiência da metodologia foi avaliada por meio de um estudo de simulação Monte Carlo, considerando diferentes cenários para os valores paramétricos. A isotonização dos dados propiciou uma melhora em todos os avaliadores de qualidade de ajuste considerados no trabalho. Dentre os modelos utilizados, o logarítmico apresentou estimativas dos parâmetros mais coerentes com os valores relatados na literatura, para os dados de deposição de Zn na tíbia de aves machos.Within the nutritional context, the supplementation of microminerals in bird food is often made in quantities exceeding those required in the attempt to ensure the proper performance of the animals

  3. Valoración de la calidad de vida tras implante de cabestrillo ajustable tipo remeex en incontinencia de orina femenina recidivada o insuficiencia esfinteriana intrínseca

    OpenAIRE

    Errando Smet, Carlos

    2013-01-01

    Se evalúa la calidad de vida (CdV) tras implante de cabestrillo suburetral ajustable (Remeex). Se analizan 54 mujeres, clasificadas mediante Prueba de la tos, Qtip, y Urodinamia en: incontinencia de orina recidivada (IOEr: 25 casos) e incontinencia esfinteriana intrínseca (IEI:29 casos). La CdV se evalúa mediante el cuestionario específico Kings Health (KH).

  4. El papel de la categorización social y las diferencias sociodemográficas en la autoestima, el ajuste y el bienestar psicológicos de una muestra de inmigrantes

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    José Andrés Peña-Pinzón

    2014-05-01

    Full Text Available Se explora el efecto de la saliencia de la categorización social inmigrante y su interacción con diferencias sociodemográficas (nivel de estudios, situación laboral, sexo de los sujetos, en ajuste psicológico, bienestar psicológico y autoestima. 210 inmigrantes de origen sudamericano, residentes en las provincias de Granada y Almería, fueron distribuidos en dos condiciones experimentales: "saliencia baja/alta de la categorización social inmigrante". Encontramos efecto de la manipulación sobre las medidas de pertenencia e identidad (autoestima colectiva, autoestima individual, ansiedad (SA-45 y bienestar laboral. Cuando la saliencia de la categorización social es baja (vs. alta, los sujetos presentan mejor autoestima, menos ansiedad y menos bienestar laboral. El sexo se asocia con la manipulación experimental en las escalas privada y pública (autoestima colectiva y en somatización, depresión y ansiedad (SA45. Los hombres para los que es menos saliente su condición de inmigrante presentan resultados más óptimos. El nivel de estudios y la situación laboral se asocian con ajuste psicológico: los sujetos sin trabajo (vs. los que están trabajando y los de estudios básicos o sin estudios (vs. los de estudios medios o superiores presentan peor ajuste.

  5. Series de días hábiles en Colombia: una aplicación al ajuste del crecimiento industrial

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    Álvaro Montenegro García

    2014-06-01

    Full Text Available Si bien muchos economistas son conscientes del efecto de los días hábiles sobre la medición de la producción, aún es frecuente encontrar que estas cifras se analizan sin el correspondiente ajuste. En general, el número de días hábiles en un mes cambia de un año a otro, lo cual es cierto para todos los meses, no solo para los que contienen la Semana Santa. Este trabajo recopila la serie de días hábiles mensuales tomando en cuenta los festivos actuales y anteriores a la Ley Emiliani, y la utiliza para ajustar la serie de producción manufacturera del DANE. Para algunos meses, la diferencia entre la cifra de crecimiento industrial reportada por el DANE y la cifra ajustada por días hábiles puede acercarse a los 12 puntos porcentuales, en cualquier dirección

  6. Cálculo, mediante la aplicación del algoritmo de ajuste por mínimos cuadrados, de los componentes de velocidad para estaciones GNSS continuas

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    Jorge Moya Zamora

    2014-07-01

    Full Text Available El cálculo de la velocidad de una estación de observación continua GNSS representa un insumo fundamental en la geodesia moderna. El hecho de determinar la posición de las estaciones GNSS de forma diaria implica que se puedan establecer las series temporales de las estaciones, con base en las cuales se puede obtener información de la influencia de fenómenos que afecten el comportamiento de estas. En este artículo se plantea una descripción del algoritmo de ajuste por mínimos cuadrados adaptado y aplicado a la determinación de los componentes de velocidad de estaciones de observación continua. Además, se aplica este algoritmo para la calcular la velocidad de la estación ETCG, perteneciente al Sistema Geocéntrico para las Américas (SIRGAS.

  7. Ajuste produtivo e medidas de flexibilização da legislação trabalhista Productive adjustment and flexibilization in the labor laws

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    Rosana Ribeiro

    2007-05-01

    Full Text Available A partir da década de 90, a introdução de inovações tecnológicas e organizacionais na indústria brasileira se intensificou significativamente. Um dos objetivos deste artigo é analisar os principais obstáculos à negociação de cláusulas referentes a essas inovações entre o sindicato dos trabalhadores da indústria de calçados, da indústria siderúrgica e da indústria têxtil e os respectivos empresários. Outro objetivo é investigar o grau de difusão das recentes medidas de flexibilização da legislação trabalhista e a estratégia desses sindicatos. Palavras-chave: Ajuste produtivo. Negociação coletiva. Flexibilização. Legislação trabalhista. During the 90’s, many new technologies and innovations in organizational structure were introduced to the Brazilian industry. One of the purposes of this article is to analyze the main obstacles to the negotiation of new labor laws in relation to theses changes between labor unions (footwear, metal and textile industry workers and the owners of the factories. The other purpose is to investigate the level of diffusion of the recent flexibilization measures of the labor legislation and the strategy of these unions. Keywords: Productive adjustment. Collective negotiation. Flexibilization. Labor laws.

  8. Caracterização dos perfis glicêmicos domiciliares como estratégia para os ajustes insulinoterápicos em pacientes com diabetes mellitus do tipo 1 Caracterización de los perfiles glicémicos domiciliares como estrategia para los ajustes insulino-terápicos en pacientes con diabetes mellitus tipo 1 Glycemic profiles in insulin adjustments in patients with type 1 diabetes mellitus

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    Sonia Aurora Alves Grossi

    2003-03-01

    Full Text Available O artigo tem como objetivo principal caracterizar os perfis glicêmicos domiciliares de pacientes com diabetes mellitus tipo1, a partir de um esquema de monitorização proposto, e adotá-los como estratégia de ajuste nas doses de insulina. Foram realizados 3259 testes, 781 antes do café, 752 antes do almoço, 765 antes do jantar, 740 antes de deitar e 221 pela madrugada. A média das glicemias nestes períodos ultrapassaram os limites superiores satisfatórios em 6,87%, 3,83%, 11,37%, 30,50% e 19,28% respectivamente. Estes dados forneceram subsídios para ajustes nos esquemas insulinoterápicos. Os níveis HbA1c não mudaram de forma significante com os ajustes realizados porém, foram mantidos em 10%.El objetivo principal de este artículo consiste en caracterizar los perfiles glicémicos domiciliares de los pacientes con diabetes mellitus tipo 1, a partir de un esquema propuesto de monitorización, para aplicarlo como estrategia, en los ajustes de las dosis de insulina. Fueron realizados 3.259 tests, de los cuales 781se hicieron antes del desayuno, 752 se realizaron antes del almuerzo, 765 antes de la merienda, 740 se hicieron antes de dormir y los 221 se hicieron en la madarugada. La media de las glicemias en estos períodos ultrapasaron los límites superiores satisfactorios em 6,8%, 3,83%, 11,37%, 30,50% y 19,28% respectivamente. Estos datos ofrecieron subsidios para poder ajustar los esquemas insulinoterápicos. Los niveles de HbA1c no variaron de forma significativa com los ajustes realizados y se mantuvieron em 10%.The goal of this paper is to characterize the glycemic profiles of patients with type 1 diabetes mellitus like a strategy in insulin adjustments. A total of 3259 tests were realized being 781 before breakfast, 752 before lunch, 765 before dinner and 740 before bed and 221 in the dawn. The average of the blood glucose tests in these periods oversteped the superior limits in 6,87%, 3,83%, 11,37%, 30,50% e 19,28% respectively

  9. Modelo experimental de bandagem ajustável do tronco pulmonar para preparo rápido do ventrículo

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    DIAS Carlos A.

    2000-01-01

    Full Text Available OBJETIVO: Um dispositivo de bandagem do tronco pulmonar (TP com ajuste percutâneo foi desenvolvido com o objetivo de induzir a hipertrofia rápida do ventrículo subpulmonar. MATERIAL E MÉTODOS: Consiste de um manguito de silicone insuflável percutaneamente, através de um botão de silicone auto-selante. Os corações de 7 cabritos jovens (peso médio: 8,7 kg foram submetidos à sobrecarga sistólica imposta pelo dispositivo e avaliados sob os aspectos hemodinâmicos, ecocardiográficos e morfológicos. Foram extraídas biópsias basais do miocárdio do ventrículo direito (VD para análise microscópica (perímetro e área do miócito. O dispositivo foi implantado no TP. As pressões do VD, TP e aorta foram monitorizadas. Após convalescença, foi iniciado o protocolo de insuflação do dispositivo de bandagem do TP. Foi injetada água destilada no botão auto-selante (via percutânea, até que a pressão sistólica do VD atingisse 70% da pressão sistólica do VE. As avaliações ecocardiográfica e hemodinâmica foram realizadas a cada 24 horas. A sobrecarga sistólica do VD foi mantida por um período de 96 horas, com insuflações progressivas no limite máximo tolerado, a cada 24 horas. Após esse período, os animais foram sacrificados para análise morfológica dos corações. Outros 9 cabritos (peso médio: 7,7 kg foram utilizados como grupo controle, para análise do peso do VD. RESULTADOS: Após 96 horas de sobrecarga sistólica do VD, foi observado um aumento do gradiente sistólico VD/TP de 10,1±4,3 mmHg para 60,0±11,0 mmHg e da pressão sistólica no VD de 22,4±4,1 mmHg para 71,0±10,0 mmHg (p<0,0001. O ecocardiograma revelou aumento da espessura muscular do VD, de 4,4±0,5 mm para 7,3±1,7 mm (p=0,001. Quando comparado ao grupo controle, houve um ganho de peso de 74% do VD submetido à sobrecarga sistólica (p<0,0001. À microscopia óptica, foi observado aumento de 27% no perímetro e de 69% na área dos miócitos (p=0

  10. Modelos para ajuste da produção de gases em silagens de girassol e milho Models for fit of gas production in sunflower and corn silages

    Directory of Open Access Journals (Sweden)

    Renius Mello

    2008-02-01

    Full Text Available O objetivo deste trabalho foi identificar entre os modelos Brody, Von Bertalanffy, Gompertz, France, Logístico, Logístico modificado e Logístico bicompartimental, aquele que apresenta maior qualidade de ajuste à curva de produção cumulativa de gases em silagens de girassol e milho. Os critérios adotados foram: coeficiente de determinação, quadrado médio do resíduo, análise gráfica das curvas observadas e estimadas, análise gráfica de dispersão dos resíduos estudentizados, erro percentual médio, eficiência relativa e número de iterações para atingir a convergência. Os modelos Brody, France e Logístico bicompartimental apresentaram os maiores valores de coeficiente de determinação em ambos os substratos, e a diferença entre eles pode ser considerada desprezível. Estes modelos apresentaram, também, os menores valores de quadrado médio do resíduo em silagens de girassol, e a diferença entre eles foi considerada desprezível. Os modelos Brody e France apresentaram menor quadrado médio do resíduo em silagens de milho. Todos os modelos apresentaram dispersão positiva dos resíduos em ambos os substratos após 144 horas de incubação. O modelo Brody apresentou menor erro percentual médio e número de iterações em ambos os substratos. Os modelos Logístico bicompartimental e France apresentaram maior eficiência relativa, respectivamente, em silagens de girassol e milho. Assim, o modelo Logístico bicompartimental apresenta maior qualidade de ajuste à curva de produção de gases em silagens de girassol e milho.The aim of this work was to identify among the Brody, Von Bertalanffy, Gompertz, France, Logistic, Modified logistic and Dual-pool logistic models, the one that presents the highest quality of fit for cumulative gas production curve in sunflower and corn silages. The quality of fit was evaluated by coefficient of determination, residual mean square, graphic analysis of the observed and estimated curves

  11. Ajuste psicosocial en agresores, víctimas puras y víctimas agresivas en la escuela. Psychosocial adjustment in aggressors, pure victims and aggressive

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    Estefanía Estévez

    2008-07-01

    Full Text Available

    En el presente estudio se examinan las diferencias entre cuatro categorías de adolescentes –agresores, víctimas puras, víctimas agresivas y estudiantes no implicados en problemas comportamentales o de victimización en la escuela– en relación con la autoestima, la sintomatología depresiva, el estrés percibido, el sentimiento de soledad, y una medida general de satisfacción con la vida. Los participantes fueron 1.319 adolescentes con edades comprendidas entre los 11 y los 16 años (47% chicos y escolarizados en siete centros públicos de enseñanza secundaria ubicados en Valencia (España. Los análisis de varianza indicaron la existencia de diferencias significativas entre las cuatro categorías de estudiantes. Así, los adolescentes no implicados mostraron un mejor ajuste psicosocial general: niveles más elevados de autoestima y satisfacción con la vida y niveles inferiores de sintomatología depresiva, estrés percibido y sentimiento de soledad. Las puntuaciones en este grupo fueron equivalentes a aquellas obtenidas por los agresores con respecto a la autoestima, la sintomatología depresiva y la soledad. Sin embargo, los agresores percibieron más estrés y expresaron menor satisfacción con sus vidas, como así también hicieron los otros dos grupos, a saber: víctimas puras y víctimas agresivas. Las víctimas mostraron los niveles más elevados de sentimiento de soledad.

    Palabras clave: Agresor, víctima, víctima agresiva, violencia escolar, ajuste psicosocial.

    The present study examined differences among four categories of adolescents –aggressors, pure victims, aggressive victims, and students not involved in behavioural or victimization problems at school– with respect to self-esteem, depressive symptomatology, perceived stress, feeling of loneliness, and a general measure of satisfaction with life. Participants were 1,319 adolescents aged from 11 to 16 years old (47% male and drawn from seven state

  12. Ajuste social y escolar de jóvenes víctimas de maltrato infantil en situación de acogimiento residencial

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    Alexander Muela

    2013-01-01

    Full Text Available El objetivo del presente trabajo consistió en examinar el ajuste social y escolar de jóvenes que habían sufrido maltrato en la infancia y se encontraban en situación de acogimiento residencial. Además, pretendíamos comprobar si existían diferencias entre los sujetos sometidos a distintas situaciones de desprotección infantil. En el estudio participaron 318 jóvenes residentes en la Comunidad Autónoma del País Vasco de edades comprendidas entre los 13 y los 18 años (M = 15.35, DT = 1.68 pertenecientes a tres colectivos. El primero de ellos estaba constituido por 69 jóvenes (31 mujeres y 38 varones víctimas de maltrato infantil que se hallaban bajo una medida de protección de acogimiento residencial. El segundo grupo estaba formado por 75 jóvenes (29 mujeres y 46 varones víctimas de maltrato infantil que se encontraban en situación de riesgo de desamparo. Por último, el tercer grupo estaba constituido por 174 jóvenes (95 mujeres y 79 varones que no habían sufrido maltrato. Los resultados pusieron de manifiesto que, independientemente de la situación de desprotección infantil en la que se encontrasen, los jóvenes víctimas de maltrato infantil mostraban mayores dificultades de adaptación social y escolar que los jóvenes que no habían sufrido maltrato en la infancia.

  13. Determinação de rotina do crômio em fezes, como marcador biológico, pelo método espectrofotométrico ajustado da 1,5-difenilcarbazida The spectrophotometric method on the routine of 1,5-diphenylcarbazide was adjusted on chromium determination in feces, after its utilization as a biological marker as chromium (III oxide

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    Hermann Bremer Neto

    2005-06-01

    Full Text Available O objetivo deste estudo foi ajustar o método espectrofotométrico da 1,5-difenilcarbazida à determinação do crômio em fezes, como marcador biológico, adequando-o à rotina laboratorial. Fatores que poderiam exercer interferência na transformação do crômio (III à crômio (VI foram testados, como a recuperação do metal, quantidade de amostra, quantidade e ordem de emprego dos ácidos oxidantes da digestão úmida, temperatura e tempo de digestão e perda por volatilização do crômio como cloreto de cromila, porém não se determinou estatisticamente interferência destes fatores. No método ajustado, a amostra é digerida pela clássica mistura ácida nítrica/perclórica, levando a oxidação do crômio (III a crômio (VI, e alíquota do extrato diluído é usado para reação com 1,5-difenilcarbazida; as absorbâncias são medidas a 550nm, utilizando-se de cubetas de um centímetro de caminho óptico, contra prova em branco conduzida simultaneamente. Dicromato de potássio foi empregado como substância de referência para obtenção da curva padrão na faixa de 0,25 - 2,5mg.mL-1 de Cr2O3 (1mg Cr2O3 º 1,9355mg K2Cr2O7.This work aims at adjusting the spectrophotometric method of 1,5-diphenylcarbazide for the determination of chromium in feces, as a biological marker. Factors that could interfere with the transformation of chromium (III into chromium (VI were tested, as the metal recovery, the sample amount, the amount and the order of use of the oxidant acids of the wet digestion, digestion temperature and digestion time, loss of chromium by volatilization as chromyl chlorid. However the interference of these factors were not statistically determined. In the adjusted method, the sample is classically digested by nitric/perchloric acid mixture leading to the oxidation of chromium (III to chromium (VI, and an aliquot of the diluted extract is used for reaction with 1,5-diphenylcarbazide; absorbance was measured at 550nm, using 1cm

  14. Variabilidade do risco do tempo de permanência ajustado para lactentes de muito baixo peso ao nascer entre centros da Neocosur South American Network Center variability in risk of adjusted length of stay for very low birth weight infants in the Neocosur South American Network

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    Guillermo Marshall

    2012-12-01

    Full Text Available OBJETIVOS: Desenvolver um modelo de predição para o tempo de permanência hospitalar (TPH em lactentes de muito baixo peso ao nascer (MBPN e comparar esse resultado entre 20 centros de uma rede neonatal, visto que o TPH é utilizado como uma medida da qualidade da assistência em lactentes de MBPN. MÉTODOS: Utilizamos dados coletados prospectivamente de 7.599 lactentes com peso ao nascer entre 500 e 1.500 g no período entre os anos de 2001 a 2008. O modelo de regressão de Cox foi empregado para desenvolver dois modelos de predição: um modelo prévio com dados do nascimento e outro posterior, que acrescenta morbidades relevantes dos primeiros 30 dias de vida. RESULTADOS: A mediana do TPH estimado e ajustado a partir do nascimento foi de 59 dias; 28 dias depois do tempo de sobrevida de 30 dias. Houve uma alta correlação entre os modelos (r = 0,92. O TPH esperado e o TPH observado variaram bastante entre os centros, mesmo depois de correção para as morbidades relevantes após 30 dias. O TPH mediano (variação: 45-70 dias e a idade concepcional na alta hospitalar (variação: 36,4-39,9 semanas refletem uma variabilidade alta entre centros. CONCLUSÃO: Um modelo simples, com fatores apresentados no nascimento, pode predizer o TPH de um lactente de MBPN em uma rede neonatal. Observou-se uma variabilidade nos TPHs considerável entre unidades de terapia intensiva neonatal. Especulamos que os resultados sejam provenientes das diferenças entre as práticas dos centros.OBJECTIVES: To develop a prediction model for hospital length of stay (LOS in very low birth weight (VLBW infants and to compare this outcome among 20 centers within a neonatal network. METHODS: Data from 7,599 infants with birth weights of 500-1,500 g born between the years 2001-2008 were prospectively collected. The Cox regression model was employed to develop two prediction models: an early model based upon variables present at birth, and a late one that adds relevant

  15. COSTA RICA EN LA ENCRUCIJADA: LOS LÍMITES DEL AJUSTE ESTRUCTURAL Y LOS URGENTES DESAFÍOS DE LA REFORMA ECONÓMICA Y SOCIAL

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    Henry Manuel Mora Jiménez

    2011-09-01

    Full Text Available Aunque en Costa Rica no se ha seguido en los últimos quince años una política económica neoliberal a ultranza, sino una “a la tica”; todo el debate económico y el accionar del sector público durante este período ha sido permeable a la lógica del ajuste estructural. Pero la actual encrucijada obliga a “tirios y troyanos”, a críticos y defensores del ajuste, a superar este enfoque aún predominante. Independientemente de los logros y fracasos acumulados desde 1983 hasta la fecha, en el campo económico y social, el país debe, urgentemente, realizar un “viraje estratégico”, pues la sensación de estancamiento o lento crecimiento de los últimos años se ha convertido en cruda realidad, con el agravante de que ya no podemos seguir viviendo del pasado. En el texto se aborda la problemática nacional en las siguientes cinco áreas:Estabilidad macroeconómica: sin ser artificial, continúa siendo frágil, dependiente en alto grado de la entrada de capitales externos y arrastrando una crisis fiscal latente que recurrentemente estalla. Esto en gran parte se explica por los rasgos de inestabilidad estructural que aun persisten.Gobernabilidad y Reforma del Estado: el estilo de gobernabilidad moldeada durante el período 1950-1975 ya no es viable, y la vacilante reforma del Estado está contribuyendo solo de manera precaria a construir nuevas formas de gobernabilidad acordes con las exigencias de las modernas sociedades democráticas. La gran tarea por delante es reconstruir un Estado estratégico y solidario; que facilite la irrupción de la sociedad civil en la vida pública nacional.Transformación productiva y competitividad: avanza, pero sin un rumbo claro y seguro, pues se adolece de una estrategia nacional de desarrollo de la competitividad internacional, que supere prácticas anticuadas de intervención estatal y viejos pero maquillados dogmas antiestatales que conducen a visiones parciales sobre el papel de las empresas y del

  16. Ajuste de modelos autorregressivos, na forma de modelos lineares dinâmicos, via inferência Bayesiana Autorregresive models fitting with a dynamic linear models approach via Bayesian inference

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    Marcelo Costa Souza

    2004-10-01

    Full Text Available Os modelos autorregressivos têm sido utilizados para as mais diversas aplicações, a maioria pela análise clássica, na qual os parâmetros são quantidades fixas, não podendo assumir variações ao longo do tempo. Com este trabalho objetivou-se a compreensão de modelos autorregressivos de ordem 2, AR(2, representados na forma de modelos lineares dinâmicos, utilizando como processo de estimação a inferência Bayesiana. O método de Cadeias de Markov Monte Carlo (MCMC foi utilizado para o cálculo das estimativas a partir da implementação dos algoritmos amostrador de Gibbs e "Forward Filtering, Backward Sampling - FFBS". Com base nos modelos AR(2, apresentaram-se o cálculo e a obtenção das distribuições condicionais completas para todos os parâmetros do modelo. Para avaliar o comportamento e a qualidade do ajuste, utilizaram-se duas cadeias de valores, cada uma com 8000 iterações, para três diferentes tamanhos de séries geradas, com 200, 500 e 800 observações. Como parte da aplicação, ajustou-se a série Canadian Lynx (NICHOLLS e QUIN, 1982 para diferentes fatores de desconto (0,90, 0,95 e 0,99, sendo o erro quadrático médio resultante utilizado para a comparação com o ajuste da mesma série, via inferência clássica. Um melhor ajuste para o modelo com fator de desconto igual a 0,99 foi observado. Considerando-se as estimativas obtidas tanto no caso simulado quanto para dados reais, obtiveram-se as previsões um passo à frente para as séries atualizada e "amostrada para trás", e para essa última, o ajuste e o erro quadrático médio comportaram-se bem melhor. Com base nos resultados obtidos, observou-se um bom ajuste dos modelos AR(2 na forma de modelos dinâmicos, via inferência Bayesiana, além de se obter uma melhor compreensão em relação à qualidade do ajuste em diferentes situações, simuladas e reais.The autoregressive models have been widely used in applications, mostly through a classical viewpoint

  17. Ajustes nos movimentos de alcançar e apreender objetos: impacto da Síndrome de Down Adjustments in the movements of reaching for and grasping objects: the impact of Down Syndrome

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    Mariana Martins dos Santos

    2012-06-01

    Full Text Available OBJETIVOS: verificar a influência das propriedades dos objetos nos ajustes realizados por lactentes típicos e com Síndrome de Down (SD dos quatro aos oito meses de idade ao alcançar e apreender objetos. MÉTODOS: 16 lactentes, avaliados uma vez ao mês dos 4 aos 8 meses, sendo oito típicos e oito com SD. Quatro objetos esféricos (maleável grande, maleável pequeno, rígido grande e rígido pequeno foram apresentados, e os cinco primeiros movimentos válidos foram registrados para análise das variáveis: ajuste proximal (uni e bimanual, ajuste distal (orientação da palma, abertura da mão e apreensão do objeto. RESULTADOS: os lactentes típicos apresentaram mais ajuste bimanual para objetos grandes aos seis e oito meses e os com SD aos sete meses. Quanto aos ajustes distais, os lactentes típicos variaram seu comportamento enquanto os com SD apresentaram uso predominante da posição oblíqua. Em geral, o grupo típico apresentou maior sucesso na apreensão dos objetos rígidos e maleável pequeno quando comparados aos lactentes com SD. CONCLUSÕES: Os lactentes com SD apresentaram menor variedade de ajustes o que levou a um menor sucesso na apreensão, possivelmente devido a restrições intrínsecas da SD.OBJECTIVES: to verify the influence that properties of objects have on the reaching and grasping adjustments made by infants with and without Down syndrome (DS between four to eight months of age. METHODS: 16 infants, eight typical and eight with DS, were evaluated once a month from months 4 to 8. Four spherical objects (large soft, small soft, large hard and small hard were offered and the first five valid movements were recorded for analysis of the variables: proximal adjustment (uni- and bimanual, distal adjustments (palm orientation, hand opening and grasping of the object. RESULTS: the typical infants displayed greater bimanual adjustment for large objects at six and eight months and those with DS at seven months. As for distal

  18. Drogodependientes vs. usuarios de salud mental con trastornos de personalidad: su relación con la calidad de vida, la psicopatología en Eje I, el ajuste psicológico y dinámica familiar

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    José Miguel Martínez-González; Pilar Munera-Ramos; Elisardo Becoña-Iglesias

    2013-01-01

    El objetivo de este estudio ha sido analizar algunas variables de gran relevancia en el tratamiento de los trastornos de la personalidad como son la calidad de vida, el nivel de gravedad de ajuste psicológico, la concomitancia con psicopatología del Eje I y la percepción de dinámica familiar de estos pacientes. La muestra la componente 68 pacientes que presentan un trastorno de la personalidad de los que el 57.4 % son drogodependientes en tratamiento en un centro ambulatorio de atención a ...

  19. El papel de la categorizaci??n social y las diferencias sociodemogr??ficas en la autoestima, el ajuste y el bienestar psicol??gicos de una muestra de inmigrantes

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    Pe??a-Pinz??n, Jos?? Andr??s; G??mez-Berrocal, Carmen; Fern??ndez-Parra, Antonio

    2014-01-01

    El objetivo general de esta investigaci??n es explorar en qu?? medida el ajuste y el bienestar psicol??gicos de las personas inmigrantes est??n relacionados de forma diferente con la valoraci??n de las identidades (personal/social) que componen el autoconcepto. Un total de 210 personas inmigrantes residentes en las provincias de Granada y Almer??a, fueron distribuidas en tres grupos que se establecieron en funci??n de dos criterios: saliencia (baja/alta) de la identidad social inmigrante y si...

  20. Ajuste e balanceamento do portfólio de projetos: o caso de uma empresa do setor químico Project portfolio adjustment and balance: a case study in the chemical sector

    OpenAIRE

    Marisa Padovani; Marly Monteiro de Carvalho; Antonio Rafael Namur Muscat

    2012-01-01

    O objetivo deste trabalho é compreender a etapa de ajuste no contexto da gestão do portfólio de projetos, destacando sua relação com os processos de categorização e balanceamento. A pesquisa realizada tem caráter qualitativo, sendo a abordagem adotada o estudo de caso longitudinal. A pesquisa foi desenvolvida em uma empresa do setor químico brasileiro. As evidências, de várias fontes, foram coletadas através de entrevistas, documentos e dados dos sistemas corporativos. Para a compreensão do p...

  1. Ajuste de modelos não-lineares em estudos de associação entre polimorfismos genéticos e crescimento em bovinos de corte Adjustment of nonlinear models in study of association between genetic polymorphisms and growth in beef cattle

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    Claudia Cristina Paro de Paz

    2004-12-01

    Full Text Available Foram utilizados dados de peso ao nascimento, ao desmame e mensais dos 8 aos 19 meses de idade de 11 classes de genótipos, formadas pela concatenação dos polimorfismos genéticos da kappa-caseína-HinfI (CSN3: AA e AB, do hormônio do crescimento-AluI (GH: LL e LV e da beta-lactoglobulina-HaeIII (LGB: AA, AB e BB (G1=AALLAA, G2=AALLAB, G3=AALLBB, G4=AALVAB, G5=AALVBB, G6=ABLLAA, G7=ABLLAB, G8=ABLLBB, G9=ABLVAA, G10=ABLVAB e G11=ABLVBB. As informações foram obtidas de animais de três grupos genéticos: ½Canchim-Nelore (CN, ½Angus-Nelore (AN e ½Simental-Nelore (SN, nascidos em 1998 e 1999 e pertencentes à Embrapa Pecuária Sudeste, São Carlos, SP. Dos cinco modelos estudados: Brody, Von Bertalanffy, Richards, Gompertz e Logístico, o último apresentou melhor qualidade de ajuste. As estimativas dos parâmetros A (valor assintótico, k (taxa de maturação e m (ponto de inflexão obtidas do modelo Logístico, ajustado para descrever o crescimento de cada animal, foram analisadas pelo método dos quadrados mínimos, por meio de um modelo linear, que incluiu, além da média geral, o efeito do genótipo, o ano de nascimento, o sexo e o manejo alimentar. Para os animais do grupo genético CN, os genótipos influenciaram significativamente as estimativas dos parâmetros A e k da curva de crescimento. O genótipo G3 apresentou valor inferior de A e superior de k em relação aos genótipos G7 e G8. Quanto aos grupos genéticos AN e SN, não foi observado efeito significativo do genótipo sobre nenhum dos três parâmetros. A aplicação da técnica de modelos não-lineares em estudos de associação entre polimorfismos genéticos e crescimento animal proporcionou uma análise detalhada do desenvolvimento dos animais de diferentes genótipos (genes: CSN3, GH e LGB.Weights at birth, at weaning and monthly from 8 to 19 months of age of the 11 genotype identified by combination of polymorphic RFLP's of the genes kappa-casein-HinfI (CSN3: AA and

  2. Ajuste do modelo de Reineke para estimativa da linha de máxima densidade na Floresta Estacional Decidual no Rio Grande do Sul

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    Evandro Alcir Meyer

    2013-08-01

    Full Text Available O objetivo deste trabalho foi estudar a relação entre a densidade de árvores por hectare e o diâmetro médio de uma Floresta Estacional Decidual, bem como ajustar o modelo Reineke para descrever esse comportamento, comparando o desempenho de diferentes métodos. A área de estudo localiza-se no Município de Silveira Martins, na região central do Rio Grande do Sul, e encontra-se em estágio inicial de sucessão, após o uso agrícola. As informações referentes ao número de árvores por hectare e ao diâmetro médio foram obtidas por meio do método de densidade pontual proposto por Spurr. As amostras foram tomadas nos estágios iniciais de uma floresta secundária, escolhendo-se áreas onde predominava o camboatá-vermelho (Cupania vernalis. Como as florestas naturais apresentam espaçamento irregular, a densidade é bastante variável. Assim, para selecionar apenas parcelas em alta densidade, foram escolhidas áreas onde se verificava a ocorrência de indivíduos mortos. Foram testados diferentes métodos para estimar o limite superior da linha de autodesbaste: a análise de regressão (para todos os dados e densidade relativa maior que 60%, corrigindo o intercepto para que os resíduos fossem negativos; o ajuste manual; o de densidade relativa (DR>90%; e a análise de fronteira estocástica. O método que melhor estimou a máxima densidade foi a análise de regressão com dados de no mínimo 60% da densidade máxima, obtendo-se um coeficiente angular de -1,563 para o modelo de Reineke. Não houve diferença significativa entre as potências fornecidas pelos diferentes métodos.

  3. Teorías e hipótesis de régimen aplicadas al estudio de ajuste dinámico de los cauces aluviales

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    Conesa García, Carmelo

    2003-06-01

    Full Text Available Geomorphic approaches to describe and explain the equilibrium alluvial river channel form, and another approache porpuses to stable «regime» channel design, have relied on simple equations relating channel dimensions to sediment grain-size, gradient and discharge. These equations are either empirical «hydraulic geometry» equations, obtained from regression analysis of the main variables sampled in natural rivers, or «rational» regime equations derived from physical theory of hydraulics and sediment transport. In this work several theories and hypothesis on the river regime are shown in order to explain the dynamic adjustments of channels in connection with environmental changes: i theory of unit stream power, ii minimum energy dissipation rate , iii dispersive-force model, iv concepts of boundary shear stress and critical bank shear, v other regime relationships. Finally, the last part is devoted to the application of the regime theories in arid and semi-arid environments, by considering it a complex aspect, of great interest in the hydro-morphologic context and until the moment little studied.

    Las aproximaciones geomórficas para describir y explicar la forma de equilibrio de un cauce fluvial y los métodos propuestos para el diseño de cauces de «régimen » estable han contado siempre con ecuaciones simples que relacionan las dimensiones del cauce con el tipo de sedimento, pendiente y caudal. Estas ecuaciones son ecuaciones empíricas de «geometría hidráulica», obtenidas a partir del análisis de regresión de variables relevantes muestreadas en cursos de agua naturales o ecuaciones «racionales » de régimen derivadas a partir de la teoría física sobre hidráulica y transporte de sedimentos. En este trabajo se muestran diferentes teorías e hipótesis de régimen para explicar el ajuste dinámico de los cauces aluviales en relación con los cambios ambientales: i teoría de energía por unidad de corriente, ii tasa m

  4. Adjustment of the infiltration curve by different empirical models Ajuste de la curva de infiltración por medio del uso de modelos empíricos diferentes Ajuste da curva de infiltração por meio de diferentes modelos empíricos

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    Carlos A. V. de Azevedo

    2009-12-01

    . Los modelos propuestos por Horton Kostiakov y Kostiakov-Lewis fueron ajustados a los datos obtenidos a campo con el infiltrómetro de anillo. Entre todos los modelos testados el de Horton presentó los mejores resultados. Entretanto, los pronósticos de los modelos Horton Kostiakov y Kostiakov – Lewis se mostraron muy similares.
    A estimativa de algumas propriedades físico-hídricas do solo, por meio do uso de modelos empíricos, constitui uma excelente alternativa para a redução do tempo e do custo das análises laboratoriais, especialmente para aplicação rápida e precisa desses valores em projetos agrícolas. O objetivo do presente trabalho é estimar a velocidade de infiltração de água no solo por meio de modelos empíricos propostos por Horton, Kostiakov e Kostiakov-Lewis e comparar os resultados com os dados obtidos em campo por meio do infiltrômetro de anel. A pesquisa foi conduzida em solo de textura arenosa da área experimental da Empresa Estadual de Pesquisas Agropecuárias – EMEPA, localizada no município de Lagoa Seca (PB. Foram realizados, ao longo da área experimental, um total de 65 testes de infiltração, por meio do infiltrômetro de anel. Os modelos de Horton, Kostiakov e Kostiakov-Lewis foram ajustados aos dados obtidos em campo com o infiltrômetro de anel. Dentre os modelos testados, o proposto por Horton foi o que apresentou o melhor desempenho. Entretanto, os prognósticos dos modelos de Horton, Kostiakov e Kostiakov-Lewis foram praticamente similares.

  5. Fluidos no período pós-operatório: efeitos da falta de ajuste ao peso corpóreo Líquidos en el período postoperatorio: efectos de la falta de ajuste al peso corporal Fluids in the postoperative period: effects of lack of adjustment to body weight

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    Alejandro Risso Vazquez

    2011-06-01

    Full Text Available OBJETIVO: Comparar as diferenças no equilíbrio hídrico e eletrolítico em pacientes com baixo e alto peso corpóreo no primeiro dia pós-operatório. MÉTODOS: Em um período de 18 meses avaliamos prospectivamente 150 pacientes durante as primeiras 24 horas após cirurgia, na unidade de terapia intensiva de um hospital universitário. Pacientes com baixo (90 kg foram comparados em termos de fornecimento e eliminação de fluidos. RESULTADOS: Não foram observadas diferenças significantes em termos de volume (4,334 ± 1,097 em versus 4,644 ± 1,957 mL/24 horas e composição dos fluidos administrados (481 ± 187 versus 586 ± 288 mEq [Na+]administrados em 24 horas. O débito urinário em 24 horas foi similar (2,474 ± 1,597 versus 2,208 ± 678 mL/24 horas, porém o grupo com baixo peso teve uma maior eliminação de eletrólitos (296 ± 195 versus 192 ± 117 mEq [Na+]urina/24 horas, p=0.0246. Quando os fluidos administrados foram ajustados ao peso corpóreo, o volume e quantidade de eletrólitos dos fluidos administrados foram maiores no grupo com baixo peso (79 ± 21 versus 47 ± 22 mL/ kg/24 horas, pOBJETIVO: Comparar las diferencias en el equilibrio de líquidos y electrolitos en los pacientes con bajo y alto peso en el primer día postoperatorio. MÉTODOS: Durante un período de 18 meses, evaluamos prospectivamente 150 pacientes, en las primeras 24 horas después de la cirugía, en una unidad de cuidados intensivos de un hospital escuela afiliado auna universidad. Se compararon pacientes con bajo ( 90 Kg en términos de ingesta y excreción urinariade agua y electrolitos. RESULTADOS: No se observaron diferencias significativas en el volumen (4,334 ± 1,097 vs. 4,644 ± 1,957 ml/24 hs. y la composición de los líquidos administrados (481 ± 187 vs. 586 ± 288 mEq [Na +]administrado/24 hs. El volumen de La diuresis en24 horas fue similar (2,474 ± 1,597 vs 2208 ± 678 ml/24 hs., pero el grupo de bajo peso mostró una mayor eliminación de

  6. Ajuste de un Modelo Hidrodinámico para una Columna con Empaques Estructurados usando Valores Experimentales Fit of an Hydrodynamic Model for a Structured Packing Column using Experimental Data

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    R.H. Chávez

    2004-01-01

    Full Text Available El objetivo del presente trabajo es ajustar un modelo hidrodinámico para columna empacada con empaque estructurado, partiendo de valores experimentales. Se comparan dos empaques, uno construido en el Instituto Nacional de Investigaciones Nucleares (ININ, de gasa de alambre de latón, y otro de la empresa Sulzer Ltda., de gasa de alambre de acero inoxidable. El modelo hidrodinámico se ajustó mediante la técnica de mínimos cuadrados con el método Levenberg-Marquardt para ecuaciones no lineales. Se obtuvieron las caídas de presión experimentales y teóricas determinadas por el modelo, así como los parámetros de ajuste del modelo tanto para el empaque ININ, como para el Sulzer BX. El empaque ININ mostró mayor caída de presión que el empaque Sulzer BX, debido a sus características geométricas. Se concluye que con la determinación de los parámetros de ajuste del modelo, se puede definir los regímenes del flujo de columnas que empleen empaque estructurado ININ y Sulzer BX.The objective of the present study is to fit a hydrodynamic model for a packed column with structured packing, based on experimental values. Two packing materials were used, one was made by the Instituto Nacional de Investigaciones Nucleares (ININ of the gauze type made of brass and the other by Sulzer Ltda., also of the gauze type but made of stainless steel. The hydrodynamic model was fit using the method of least squares using the Levenberg and Marquardt methodology for non-linear equations. Experimental and theoretical pressure drops were determined using the model, as well as the fitted parameters of the model both for ININ and Sulzer BX packings. The ININ packing has a higher pressure drop than the Sulzer BX, due to its geometric characteristics. It is concluded that by using the fitted parameters of the model, flow regimes in the column may be defined when using ININ or Sulzer BX structured packing

  7. Ajuste do modelo Chistiansen-Hargreaves para estimativa da evapotranspiração do feijão no cerrado Chistiansen-Hargreaves model adjustment for estimating evapotranspiration of bean crop in the Cerrado region

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    Omar C. Rocha

    2003-08-01

    Full Text Available Os produtores de feijão da região do Cerrado contam com apenas uma tecnologia, já estabelecida, para o manejo das irrigações: a tensiometria. Muito embora essa metodologia tenha alto potencial de uso não tem sido amplamente adotada pelos produtores, razão pela qual a utilização de modelos de estimativa de evapotranspiração tem se mostrado bastante aplicável à realidade da região. Assim, este trabalho tem o objetivo de avaliar o desempenho do modelo Chistiansen-Hargreaves na estimativa da evapotranspiração da cultura do Feijão Preto, no período seco do Cerrado brasileiro, almejando colocar à disposição dos produtores um modelo ajustado, que permita um manejo eficiente da irrigação no sistema produtivo da região. A evapotranspiração do feijoeiro foi medida com um lisímetro de pesagem. O experimento foi conduzido na Embrapa Cerrados, localizada em Planaltina, DF, Brasil. Quando calculado com coeficientes de cultura determinados na pesquisa e testado com o termo energético ajustado (S0 = 0,5 o modelo apresentou ótimo desempenho podendo, nesta condição, ser empregado com segurança no manejo de irrigação.Bean producers from the Brazilian Cerrado region have only one technology for the irrigation management: the measurement of the water tension in the soil through the use of tensiometers. Although this methodology has high potential, it has not been widely adopted by the producers. Thus, the utilization of models to estimate evapotranspiration estimate has shown to be applicable to the Cerrado region. So, this paper aims to evaluate the performance of the Chistiansen-Hargreaves model to estimate evapotranspiration of black bean crop in the dry season of the Brazilian Cerrado region. It also aims to provide producers an the adjusted model to estimate evapotranspiration which permit an efficient management for the agricultural irrigated system of the Cerrado region. The evapotranspiration of the black bean crop was

  8. Comparação de métodos para ajuste de modelos de semivariograma da precipitação pluvial anual Comparison of methods for adjusting semivariogram model of annual rainfall

    OpenAIRE

    José R. P. de Carvalho; Sidney R. Vieira; Célia R. Grego

    2009-01-01

    Comumente dados de precipitação pluvial apresentam variação e a obtenção da estimativa de sua distribuição espacial é primordial no planejamento agrícola e ambiental. O objetivo neste trabalho foi comparar o método de estimação dos mínimos quadrados ponderados para ajuste de modelos ao semivariograma com o método de tentativa e erro, através da técnica de auto-validação "jack-knifing", para dados de precipitação pluvial média anual do Estado de São Paulo. Observações de precipitação correspon...

  9. Propuesta de un procedimiento de operación para la participación de la demanda industrial en los mercados de servicios de ajuste del sistema eléctrico

    OpenAIRE

    Piñas García, Miguel Ángel

    2013-01-01

    Desde la creación de Red eléctrica de España (REE) en “1985” seguido por la liberación del sector eléctrico en “1998 y posteriormente en “2003”, con la creación de los mercados de los servicios de ajustes del sistema eléctrico, el operador del sistema viene garantizando la seguridad del suministro, y la coordinación de la producción y el transporte de electricidad. Debido a la continua penetración de las energías renovables no gestionables y a la incertidumbre de la demanda,...

  10. Influência do tamanho e da rigidez dos objetos nos ajustes proximais e distais do alcance de lactentes Influence of object size and rigidity on proximal and distal adjustments to infant reaching

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    NACF Rocha

    2006-09-01

    Full Text Available CONTEXTUALIZAÇÃO: Estudos têm identificado que as propriedades dos objetos induzem os ajustes no alcance; no entanto, poucos investigaram a influência específica do tamanho e rigidez dos objetos em lactentes jovens. OBJETIVO: Verificar se lactentes de 4 a 6 meses realizam ajustes proximais e distais ao alcançarem objetos de diferentes tamanhos e rigidez. MÉTODOS: Nove lactentes saudáveis foram posicionados em uma cadeira inclinada a 50º. Quatro objetos foram apresentados, um rígido grande (RG, um rígido pequeno (RP, um maleável grande (MG e um maleável pequeno (MP, por um período de 1 minuto cada. Em um total de 384 alcances, foram analisados os ajustes proximais (alcance uni e bimanual e distais (orientação da mão horizontal, vertical e oblíqua; mão aberta, fechada e semi-aberta e o sucesso do alcance dos objetos. RESULTADOS: Constatou-se ajuste bimanual para o objeto RG e unimanual para os demais. A orientação da mão oblíqua foi predominante no toque dos objetos, enquanto para a preensão dos mesmos, a predominância foi a vertical, principalmente para o objeto RG. A orientação horizontal não foi observada na preensão do objeto RG. A mão semi-aberta foi mais freqüente no início do alcance para todos os objetos, enquanto no toque do objeto RG a mão aberta foi predominante. O sucesso do alcance foi maior para os objetos maleáveis (MG, MP do que para os rígidos (RG e RP. CONCLUSÃO: Lactentes jovens estudados são capazes de planejar e ajustar seus movimentos baseados na percepção das propriedades físicas dos objetos, o que sugere interação percepção-ação.BACKGROUND: Studies have identified that object properties lead to adjustments to reaching. However, few have investigated the specific influence of object size and rigidity among young infants. OBJECTIVE: To verify whether four to six-month-old infants make proximal and distal adjustments when reaching for objects of different sizes and rigidity. METHOD

  11. Ajuste osmótico em milho cultivado em diferentes sistemas de manejo de solo e disponibilidade hídrica Osmotic adjustment in maize cultivated in different soil tillage systems and water availability

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    Cleusa Adriane Menegassi Bianchi

    2005-07-01

    Full Text Available A cultura do milho é sensível ao déficit hídrico, e esta é uma causa freqüente de redução na produção de grãos. O objetivo deste trabalho foi verificar a ocorrência de ajuste osmótico em milho, cultivado em dois sistemas de manejo do solo, com diferentes disponibilidades hídricas. Os tratamentos consistiram do cultivo do milho em semeadura direta (SD e convencional (SC, com irrigação de forma a manter a umidade do solo próxima à capacidade de campo, e sem irrigação. O ajuste osmótico foi obtido pela diferença do potencial osmótico hidratado entre as plantas irrigadas e sem irrigação. Os maiores valores de potencial mínimo de água na folha ocorreram em plantas cultivadas sob SD, em razão do maior potencial matricial da água no solo nesse sistema. O potencial de pressão e o osmótico hidratado diminuíram em conseqüência do déficit hídrico, o que determinou a ocorrência de ajuste osmótico em ambos os sistemas, que foi mais intenso em manejo convencional. Portanto, o potencial mínimo de água na folha demonstra ser um indicador adequado da condição hídrica das plantas de milho. A cultura apresenta tolerância ao déficit hídrico por meio do mecanismo de ajuste osmótico.Maize is a very sensible crop to water deficit, which is a frequent cause of reduction in its grain yield. The objective of this work was to verify the occurrence of osmotic adjustment in maize cultivated in different soil management systems and water availability. The maize was cropped in no-tillage (NT and conventional tillage (CT, with irrigation and no-irrigation. For measurements of minimum leaf water potential, a pressure chamber was utilized. Osmotic adjustment was calculated as the difference between osmotic potentials at full turgor, in irrigated and non-irrigated plants. Highest values of minimum leaf water potential were found in plants cropped in NT, as a response to the highest soil potential on this cropping system. Pressure

  12. O formante do cantor e os ajustes laríngeos utilizados para realizá-lo: uma revisão descritiva The singer's formant and the laryngeal adjustments used to realize it: a descriptive review

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    Cristina de Souza Gusmão

    2010-01-01

    Full Text Available Este estudo descreve, através da literatura da Fonoaudiologia e da Física Acústica, alguns aspectos relacionados à produção da voz, tais como o espectro do som como a frequência fundamental, os harmônicos, os formantes e também os ajustes laríngeos. A revisão de literatura inclui a descrição anátomo-fisiológica do aparelho vocal, suas funções e mecanismo para produção vocal. Descreve também os aspectos relacionados à espectografia do som, da localização dos formantes e de ajustes anatômicos e musculares para se obter o formante do cantor. Este estudo visa esclarecer conceitos e levantar questionamentos sobre o que ocorre na fisiologia vocal e o que é dito e aceito pelo senso comum sobre o formante do cantor.This study describes some voice production aspects, like sound spectrum as the fundamental frequency, harmonics, the formants and also the laryngeal adjustments through the phonoaudiology and acoustics literature. The literature review includes the anatomical and physiological description of the vocal apparatus, its functions and the mechanism for the vocal production. It also describes related aspects of the sound spectrographs, to the formants location and to the anatomical muscle adjustments to realize the singer's formant. This study aims at clarifying concepts and raising questions about what happens in vocal physiology and what is said and accepted by the common sense about the singer's formant.

  13. Programa de ajuste multiparamétrico de curvas de titulação potenciométricas de ácidos húmicos Multiparametric adjustment program of potentiometric titration curves of humic acids

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    Clausius Duque Gonçalves Reis

    2010-04-01

    Full Text Available Tendo em vista a dificuldade de determinação dos pontos de inflexão na curva de titulação potenciométrica de ácidos húmicos, por metodologias tradicionais, foi desenvolvido foi desenvolvido um programa na linguagem Delphi para ajuste multiparamétrico de dados de titulação potenciométrica. Para isso um processo iterativo para estimar as raízes de um polinômio, com base no método de Newton-Raphson, foi utilizado. Os dados das titulações potenciométricas de ácidos húmicos usados nas regressões foram obtidos em um sistema automatizado de titulação potenciométrica. O programa desenvolvido na linguagem Delphi permite maior versatilidade e facilidade de operação, com uma interação mais amigável com o usuário. As curvas de titulação potenciométricas ajustadas sobrepuseram-se quase que totalmente às curvas experimentais. Os valores de pKa e as percentagens de grupos tituláveis dos ácidos húmicos, parâmetros ajustáveis na regressão multiparamétrica, apresentaram valores comparáveis com dados da literatura.Regarding the difficulty of determining the inflection points in the potentiometric titration curve of humic acids by means of traditional methodologies, a Delphi program a Delphi program was developed for the multiparametric data adjustment in potentiometric titration. For this purpose, an iterative process was used, based on the Newton-Raphson method to estimate the roots of a polynomial. The humic acid potentiometric titration data, used in regressions, were obtained in an automated system of potentiometric titration. The program developed in Delphi language features greater versatility, ease of operation and better interaction with the user. The adjusted potentiometric titration curves overlap the experimental curves almost entirely. The pKa values and percentages of titrable groups of humic acids extracted from soil, adjustable parameters in the multiparametric regression, were comparable with those reported

  14. RETIRO LABORAL Y AJUSTE A LA JUBILACIÓN DE HOMBRES Y MUJERES EN LA MEDIANA EDAD (WORK RETIREMENT AND ADJUSTMENT TO RETIREMENT OF MEN AND WOMEN IN THE MIDDLE-AGED

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    Cruz Meléndez Roxana

    2011-04-01

    Full Text Available Resumen:En este artículo se presentan los resultados de una investigación aplicada cuyo objeto de estudio fue un grupo de hombres exfuncionarios y mujeres exfuncionarias del área administrativa de la Universidad de Costa Rica (UCR que se encuentran en la etapa de vida denominada “la mediana edad” y que enfrentan el proceso trabajo-retiro laboral. El estudio consistió en identificar los principales factores que inciden en el retiro laboral a una edad más temprana; la viviencia del proceso, el ajuste a la jubilación y sus implicaciones a nivel personal y social. La información recopilada se obtuvo a partir de la técnica “la entrevista fenomenológica” concebida como una exploración profunda que proporciona datos de gran valor conceptual y humana; en ella, tanto la persona que entrevista como la entrevistada mantienen un compromiso para que la búsqueda de la información sea dentro de una relación empática. Partiendo de lo subjetivo por su historia de vida al mandato social por lo roles asignados y asumidos por la población en estudio. Los resultados obtenidos indican que pareciera que la valoración que cada uno de los participantes hace de su rol laboral y el significado del trabajo en sus vidas es determinante en el proceso de retiro laboral y su ajuste al rol de persona jubilada.Abstract: This article presents the results of applied research study that was aimed at a group of men and women, former administrative staff of the University of Costa Rica that are in the stage of life called middle age and facing work-retirement process work. The study consist in identify the main factors affecting the removal from work at a younger age, the experiencing process, adjustment to retirement and its implications for personal and social level. Information collected was obtained from the technique "the phenomenological interview “conceived as a deep exploration that provides valuable data conceptual and human, in her interview both

  15. A tecnologia da informação como suporte ao ajuste da previsão da demanda: um estudo de caso em uma empresa de bebidas carbonatadas

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    Alexandre Pereira Salgado Junior

    2010-08-01

    Full Text Available A gestão da cadeia de suprimentos é um problema que sempre instigou gestores por todo o mundo, ademais os modelos de previsão da demanda tradicionais não mais satisfazem os novos desafios da gestão dos estoques e da ruptura. Assim, novas soluções foram desenvolvidas, buscando-se melhorar os níveis de serviço prestados ao consumidor final. Dentre elas, destaca-se a utilização da TI que, por disponibilizar a informação em tempo real, pode contribuir para o ajuste dos modelos tradicionais de previsão da demanda. Desta forma, o objetivo desta pesquisa é analisar como a TI pode ajudar o segmento de bebidas a ajustar sua previsão de demanda. O método de pesquisa utilizado foi o estudo de caso, analisando uma empresa de bebidas carbonatadas, escolhida por conveniência. Para análise dos dados, utilizou-se a técnica de análise de conteúdo. Como principais resultados destacam-se melhorias no nível dos estoques, na ruptura e no nível de serviço.

  16. Sistemas homogéneos de ecuaciones diofánticas. Resolución y aplicación al ajuste automático de reacciones químicas

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    Recuero, Alfonso

    1984-06-01

    Full Text Available An algorithm to solve systems of linear homogeneous diophantine equations is given here. Subsequently, as an example of application, a method of heuristic search for the best solution is described; this fulfils certain conditions within an infinite space of solutions of various dimensions. Finally, an application of the algorithm and of the process of heuristic search for the best solution in adjusting chemical reactions is described. The listing in BASIC of the program of application mentioned is included, for the HP-75 portable computer.

    Se presenta un algoritmo de resolución de sistemas de ecuaciones diofánticas lineales y homogéneas. Seguidamente y como ejemplo de aplicación se describe un método de búsqueda heurística de una solución óptima que cumpla unas ciertas condiciones dentro de un espacio infinito de soluciones de varias dimensiones. Por último se describe la aplicación del algoritmo y del procedimiento de búsqueda heurística para el caso de ajuste de reacciones químicas. Se incluye el listado en BASIC del programa para el ordenador HP-75.

  17. Uso de modelos não-lineares para o ajuste de curvas de crescimento de cavalos pantaneiros Using nonlinear models to describe height growth curves in pantaneiro horses

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    Sandra Aparecida Santos

    1999-07-01

    Full Text Available Dados de altura da cernelha e idade de 26 cavalos Pantaneiros, obtidos, na maioria, do nascimento até 36 meses, foram ajustados aos modelos de respostas não-lineares de Brody, Richards, Gompertz, Logístico, Weibull e Morgan-Mercer-Flodin. Estes seis modelos matemáticos foram comparados com o uso de uma medida de curvatura média e do erro médio quadrático combinado. O modelo de Weibull foi escolhido. A assíntota desta curva representa a altura esperada na maturidade. Os machos apresentaram um valor maior desta quantidade do que as fêmeas. O índice de maturidade, contudo, é maior para as fêmeas. Observou-se uma indicação de associação negativa entre altura na maturidade e índice de maturidade somente nas fêmeas. Tais resultados indicam que as fêmeas amadurecem mais cedo. Após testes de normalidade e homogeneidade de variância, as diferenças entre sexos foram analisadas com o uso do teste-t. Somente a altura da cernelha ao nascimento apresentou diferença significativa.Height at withers data mostly from birth to 36 months of age of 26 Pantaneiro horses were used to fit Brody, Richards, Gompertz, Logistic, Weibull and Morgan-Mercer-Flodin nonlinear response functions. Based on measures of average curvature and combined mean square error, the Weibull model was chosen. The asymptote of this curve, representing the average height at maturity, was higher for males than females. The maturity index, however, was more elevated for females than males. There was indication of a negative association between the maturity index and height at maturity only for females. These results indicate that females mature earlier. After checking for normality and homogeneity of variances within groups (sex the analysis investigated sex differences via t-tests. A significant difference was detected only for height at birth.

  18. Ajuste do modelo fototérmico de estimativa do desenvolvimento e do índice de área foliar de soja Adjustment of the photothermic model to estimate soybean development and leaf area index

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    Neila T. Toledo

    2010-03-01

    Full Text Available Visou-se neste estudo, realizar o ajuste do modelo de estimativa do desenvolvimento de populações de soja e da variação do índice de área foliar para a variedade IAS 5. Como fonte de variação na velocidade de desenvolvimento, diferentes épocas de plantio foram utilizadas em experimentos nos anos agrícolas de 2004/2005 (três datas e 2005/2006 (quatro datas no IRDeR (Instituto Regional de Desenvolvimento Rural localizado em Augusto Pestana, RS (28º 27' 17" S e 53º 54' 50" W, nos quais foram identificadas as datas em que ocorreram as principais fases do desenvolvimento da cultura da soja, seguindo a Escala Fenológica de Fehr & Caviness e estimados o índice de área foliar em quatro momentos: no final do período de instalação da população vegetal (V6; no início do florescimento (R1; início do enchimento de grãos (R5; e no início da maturação (R7. As variáveis meteorológicas temperaturas mínima e máxima diárias foram coletadas. Após o ajuste dos coeficientes genéticos, o modelo foi formatado no programa Stella 5.0. O modelo de estimativa do desenvolvimento da soja teve desempenho satisfatório, apresentando estimativas precisas para os dados que o determinaram. O modelo de estimativa do índice de área foliar apresentou estimativas satisfatórias.The present study was carried out to adjust the soy population development model and the leaf area index model for the IAS 5 cultivar. Different sowing dates were used in two experiments as source of development variation during 2004/2005 (three dates and 2005/2006 (four dates in the IRDeR (Instituto Regional de Desenvolvimento Rural located in Augusto Pestana, in the State of Rio Grande do Sul (28º 27' 17" S and 53º 54' 50" W. The main crop development phases were identified according to the Feher & Caviness phenological scale, and the leaf area index was determined in four occasions: at the final period of plant population installation (V6; at the beginning of flowering

  19. Observador Asintótico Ajustable para Reactores Bioquímicos: Aplicación a la Digestión Anaerobia A Tunable Asymptotic Observer for Biochemical Reactors: Application to Anaerobic Digestion

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    V. Alcaraz

    2004-01-01

    Full Text Available En este trabajo se propone un observador asintótico ajustable para sistemas dinámicos no lineales que pueden ser descritos por un conjunto de ecuaciones diferenciales ordinarias. A diferencia de los observadores asintóticos clásicos, este observador está provisto de ganancias variables que pueden ser ajustadas por el usuario. En la etapa inicial de la estimación, este observador es robusto frente a perturbaciones inducidas por un conocimiento parcial de los términos no lineales. Eventualmente, este observador es totalmente independiente de los términos no lineales, lo que le confiere una robustez total frente a cualquier perturbación inducida por estos términos. El observador es probado mediante simulaciones rigurosas y es aplicado a un modelo dinámico de digestión anaerobia para el tratamiento de aguas residuales, mostrando propiedades excelentes de convergencia, estabilidad y desempeño. La respuesta del observador propuesto es más rápida que la obtenida con los observadores asintóticos clásicosIn this paper a tunable asymptotic observer for non-linear dynamic systems that can be described by a set of ordinary differential equations, is proposed. In contrast with classical asymptotic observers, this one is provided with variable gains that can be tuned by the user. At the first stage of the estimation, the observer is robust against disturbances induced by poorly known non-linear terms. Eventually, the observer becomes fully independent of the nonlinear terms and thus robust against any disturbance induced by the nonlinear terms. The performance of the observer is tested through rigorous simulations in a dynamic anaerobic digestion model for wastewater treatment, showing excellent convergence and stability properties. Finally, it is shown that the proposed observer yields faster estimates than those obtained by using the classical asymptotic observers

  20. Abordagem multidisciplinar de pacientes obesos mórbidos submetidos a tratamento cirúrgico pelo método da banda gástrica ajustável Multidisciplinary approach to morbidly obese patients undergoing surgical treatment by adjustable gastric banding

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    Denis Pajecki

    2010-10-01

    Full Text Available OBJETIVO: Avaliar o resultado do tratamento cirúrgico de pacientes obesos mórbidos pelo método da BGA, acompanhados em ambulatório multidisciplinar. MÉTODOS: Foram estudados 20 pacientes com IMC que variou de 36,6 a 72 kg/m2 (X=47,51 +/- 6,1 e idade entre 36 a 60 anos, submetidos à colocação de BGA. As comorbidades encontradas no pré-operatório foram hipertensão arterial (nove, diabetes tipo II (quatro, apneia do sono grave (um, hipertrigliceridemia (quatro e problemas ortopédicos graves (três. No seguimento pós-operatório os pacientes foram atendidos em ambulatório multidisciplinar (cirurgião, endocrinologista, psiquiatra e nutricionista. Nos primeiros seis meses, a orientação foi de visitas mensais para ajustes da banda e orientação nutricional. Após, as visitas ocorreram a cada dois ou três meses, conforme a necessidade. RESULTADOS: O tempo cirúrgico variou de 40 a 180 minutos; o de internação de 1 a 10 dias (X = 36 horas. Duas pacientes necessitaram reintervenção cirúrgica por complicações tardias: uma rotação do portal e um deslizamento superior da banda . O tempo de seguimento variou de 28 a 36 meses. A perda de peso média foi de 29,26 kg +/- 8,8, ou 24,37% +/- 6,1 do peso inicial e 49,16% +/- 11,3 do excesso de peso. O IMC médio variou de 47,51 para 34,88. Houve melhora global das comorbidades, mais acentuada nos pacientes com maior perda de peso. CONCLUSÃO: Os resultados obtidos foram satisfatórios para a maioria dos pacientes nos quesitos perda de peso e melhora das comorbidades.OBJECTIVE: To evaluate the outcome of the surgical treatment of morbidly obese patients by Adjustable Gastric Banding (ABG followed in a multidisciplinary clinic. METHODS: We studied 20 patients with BMI ranging from 36.6 to 72 kg/m2 (X = 47.51 + / - 6.1 and aged between 36 to 60 years, undergoing placement of AGB. Preoperative comorbidities were hypertension (nine, type II diabetes (four, severe sleep apnea (one

  1. CLINICAL BIOCHEMISTRY

    Science.gov (United States)

    Assessment of the health status of animals through measurement of cellular, biochemical, and macromolecular constituents in blood, secretions, and excretions has been variously referred to as clinical chemistry, clinical biochemistry, or clinical pathology. he genesis of this dis...

  2. Reorganização dos ajustes posturais antecipatórios em indivíduos após AVE: influência de um programa de intervenção em fisioterapia no registo electromiográfico do tibial anterior e solear

    OpenAIRE

    Rodrigues, Sónia

    2010-01-01

    Introdução: As dificuldades encontradas em individuos após Acidente Vascular Encefálico, ao nível da marcha, influenciam significativamente o retorno ao trabalho, a participação na comunidade ou o desempenho nas actividades da vida diária. Objectivo: Neste trabalho, procurou-se verificar qual o efeito de um programa de intervenção em fisioterapia nos ajustes posturais antecipatórios que ocorrem previamente ao movimento voluntário e assim pré-determinar a sua contribuição para a...

  3. Preparo do ventrículo subpulmonar através de dois diferentes modelos ajustáveis de bandagem do tronco pulmonar: estudo experimental Preparation of the pulmonary ventricle for arterial switch operation using two adjustable devices for pulmonary trunk obstruction: an experimental study

    OpenAIRE

    Luiz Fernando CANÊO; DIAS Carlos A.; ASSAD Renato Sammy; Maria Cristina Donadio ABDUCH; Aiello, Vera Demarchi; Moreira, Luiz Felipe Pinho; LOURENÇO FILHO Domingos D.; Noedir A. G Stolf

    2001-01-01

    Dois modelos de dispositivos ajustáveis foram implantados em cabritos jovens, com o objetivo de avaliar suas capacidades de bandagem do tronco pulmonar (TP) e eficiência no treinamento do ventrículo subpulmonar. Foram utilizados 3 grupos de 7 animais, submetidos ao implante de cateter balão (grupo I), implante de dispositivo de bandagem externa (grupo II) e para obtenção dos pesos dos ventrículos direito (VD), esquerdo (VE) e septo interventricular em condições normais (grupo controle). Os an...

  4. Ajuste do método de Priestley-Taylor às condições climáticas locais Adjustment of the Priestley-Taylor method to local climatic conditions

    Directory of Open Access Journals (Sweden)

    Nilson A. Villa Nova

    2006-08-01

    Full Text Available A sustentabilidade da agricultura irrigada depende primariamente do manejo eficiente da irrigação, de modo a aumentar a produtividade primária de uma cultura em determinada localidade. A eficiência no uso de água pode ser melhorada pelo próprio esquema de irrigação adotado, sendo essencialmente governado pelas condições climáticas. O planejamento da irrigação e a tomada de decisão são funções do conhecimento da demanda evaporativa da atmosfera, sendo expressa pela demanda potencial (ETo. Em geral, quase todos os métodos de estimativa de ETo reportados na literatura referem-se a valores diários, incluindo-se nessa situação as perdas noturnas de evaporação, as quais serão expressivas apenas em alguns dias após a chuva ou irrigação. Desenvolveu-se, no presente estudo, método corrigido para estimar ETo, baseado no balanço de energia local, a partir de dados meteorológicos monitorados em postos de observação de superfície durante o período de luz. Para validação do método de Priestley-Taylor ajustado às condições locais, foram utilizados dados observados em estação meteorológica automática instalada em Piracicaba - SP, bem como medidas lisimétricas coletadas na Fazenda Areião da área experimental da ESALQ/USP. Estudos de regressão revelaram que o método proposto apresentou excelentes resultados quando comparado com o método de Penman-Monteith e com medidas realizadas em lisímetros de pesagem com célula de carga, dados os elevados valores de coeficiente de determinação obtidos, podendo ser recomendado, portanto, em estudos de avaliação de consumo de água das culturas em diversas localidades.The sustainability of irrigated agriculture depends primarily on the efficient management of irrigation in order to increase the crop primary productivity in a given site. The efficiency in water use can be enhanced by the irrigation schedule adopted, being mainly governed by the climatic conditions. The

  5. Evaluación del grado de ajuste de las revistas científicas españolas de ciencias de la salud a las normas internacionales de presentación de publicaciones periódicas

    Directory of Open Access Journals (Sweden)

    López-Cózar Emilio Delgado

    1997-01-01

    Full Text Available FUNDAMENTO: Se evalúa el cumplimiento, por parte de 205 revistas científicas españolas de ciencias de la salud, de las normas internacionales de presentación de publicaciones periódicas, con el fin de mejorar su calidad informativa, puesto que la normalización constituye un elemento importante en el éxito del proceso de transferencia de la información científica. MÉTODOS: Las revistas se identificaron a través de cinco bibliografías impresas y cuatro bases de datos bibliográficas. Se controlaron 136 preceptos extraídos de las normas internacionales de presentación de publicaciones periódicas emitidas por la International Standardization Organization (86% y de recomendaciones generadas por la UNESCO, el International Committee of Medical Journal Editors, el Council of Biology Editors y EJ Huth (14%. Para cada parámetro se valoraron tres niveles de evaluación (Inclusión, Presentación y Ubicación, por lo que el número total de ítemes evaluados fue de 342. RESULTADOS: El grado de normalización de las revistas biomédicas españolas estudiadas fue del 33,5% ± 8,5. Destacan por su buen ajuste los parámetros referidos a la identificación de la revista en las páginas del texto y al sumario del fascículo. Los aspectos más descuidados se concentran en el volumen y sumario analítico. Las revistas peor normalizadas son las auspiciadas por empresas y organismos de gestión. Las revistas anuales son las mejor estandarizadas. CONCLUSIONES: El bajo nivel de normalización que resulta no se debe a un deficiente cumplimiento generalizado de todos los parámetros sino más bien al incumplimiento completo de algunos de los mismos, en concreto: las normas que regulan el sumario analítico y la cubierta, sumario e índices de volumen. Para conseguir una mayor normalización de las revistas se propone un cambio en la política de difusión de las normas, la elaboración de guías y manuales para la confección de publicaciones cient

  6. LA REFORMA ECONÓMICA Y SU IMPACTO SOCIAL EN COSTA RICA DURANTE EL PERÍODO DE AJUSTE ESTRUCTURAL: apuntes críticos para el análisis

    Directory of Open Access Journals (Sweden)

    Rafael Arias Ramírez

    2007-12-01

    Full Text Available Resumen El objetivo de este artículo es analizar la reforma económica implementada en Costa Rica en los últimos veinticinco años como resultado de la aplicación de los programas y políticas de ajuste estructural. Para tal efecto se analiza el debate que acompañó el proceso de aprobación e implementación de los mencionados programas, el discurso de los mismos, su desempeño y algunos de sus principales efectos sociales. Esta reforma económica representó un cambio importante en el estilo de desarrollo y en las funciones del estado social vigentes desde la década de los 1950s. De ahí que resulte de gran interés analizar cuál fue el nuevo enfoque de desarrollo que se implementó a partir de la década de los años ochenta y los resultados del mismo en materia de crecimiento económico y equidad social. Esta publicación pretende servir de insumo para promover la tarea académica de repensar la política de desarrollo que la sociedad costarricense debe definir dentro del nuevo contexto de la globalización.   Abstract The objective of this article is to analyze the economic reform implemented in Costa Rica in the last twenty-five years as result of the application of the structural adjustment programs and policies. For such effect we analyze the debate that accompanied the process of approval and implementation of the mentioned programs, the speech of such, its performance and some of its main social effects. This economic reform represented an important change in the style of development and in the current functions of the social state from the decade of 1950s. Hence it results of big interest to analyze which was the new approach of development that was implemented from the decade of the eighties and the results of the same one on the subject of economic growth and social equity.This publication tries to serve as input to promote the academic task of rethinking the politics of development that the Costa Rican society must define

  7. Disputas, ajustes e acomodações na produção da agenda eleitoral: a cobertura jornalística ao Programa Bolsa Família e as eleições de 2006

    Directory of Open Access Journals (Sweden)

    Flávia Biroli

    2010-06-01

    Full Text Available Resumo: Este artigo apresenta uma análise da cobertura jornalística ao Programa Bolsa Família durante as eleições presidenciais de 2006. A pesquisa abrange um total de 166 textos que mencionaram o Programa, publicados pelos jornais O Globo, O Estado de São Paulo, Folha de São Paulo e Valor Econômico entre os dias 1º de setembro e 31 de outubro de 2006. Discutimos a dinâmica de produção da agenda eleitoral, observando as disputas, ajustes e acomodações que constituem a cobertura. A análise conjunta das vozes e dos enquadramentos presentes no material permite observar aspectos relevantes das interações entre os campos da mídia e da política no contexto em que a cobertura foi realizada. As conclusões ressaltam a baixa pluralidade do noticiário, associada a representações das eleições de 2006 e da democracia brasileira que têm como aspectos centrais a estigmatização dos eleitores de baixa renda e dos beneficiários de programas sociais.Abstract: This article presents an analysis of the news about an important social program maintained by the federal government, Programa Bolsa Família, in the period of brazilian major elections of 2006. The study is based in 166 texts published in the newspapers O Globo, O Estado de São Paulo, Folha de São Paulo e Valor Econômico between September 1st and October 31st. We discuss the production of electoral agenda, observing disputes, adjustments and acommodations that constitute news coverage. The analysis of voices and framings in the texts leads to the observation of relevant aspects of the relations between media and politics at that moment. Conclusions underline the low plurality in press coverage, connected to representations of the elections of 2006 and Brazilian democracy that include stigmatization of low income voters and beneficiaries of social programs.

  8. Clinical biophysics

    Energy Technology Data Exchange (ETDEWEB)

    Anbar, M.; Spangler, R.A.; Scott, P.

    1985-01-01

    Chapters are included on clinical decision making, principles of biomedical engineering, computers and their medical uses, clinical radiobiology, diagnostic x-ray radiology, clinical applications of ultrasonics, nuclear medicine, NMR imaging, diagnostic imaging, bioelectric techniques in diagnosis and therapy, biophysical aspects of the clinical laboratory, and biophysical aspects of modern surgery.

  9. A mortalidade materna nas capitais brasileiras: algumas características e estimativa de um fator de ajuste Maternal mortality in Brazilian State Capitals: some characteristics and estimates for an adjustment factor

    Directory of Open Access Journals (Sweden)

    Ruy Laurenti

    2004-12-01

    Full Text Available A mortalidade materna pode ser considerada um excelente indicador de saúde, não só da mulher, mas da população geral; mostra, também, iniqüidades. A redução da mortalidade materna é uma das principais metas, estando também incluída nas Metas do Desenvolvimento do Milênio da ONU. OBJETIVO: Conhecer a qualidade da informação da mortalidade de mulheres de 10 a 49 anos, e estimar a razão de mortalidade materna (RMM e os fatores de ajuste para os dados oficiais, no conjunto das capitais de estados brasileiros e Distrito Federal. METODOLOGIA: Adotou-se a metodologia RAMOS (a partir da declaração de óbito, entrevista no domicílio da mulher falecida, com preenchimento de questionário, sobre variáveis demográficas, epidemiológicas, clínicas e de acesso a serviços; seguiam-se consultas a prontuários médicos hospitalares e a laudos de autópsia. Após o resgate da informação, pôde ser feita análise das reais causas básicas, terminais e associadas. A população de estudo foi estimada em 7.332 mortes de mulheres de 10 a 49 anos, ocorridas no primeiro semestre de 2002, sendo 239 óbitos por causas maternas. A RMM foi de 54,3 por cem mil nascidos vivos (n.v., no conjunto de capitais, variando entre 42 por cem mil n.v. no Sul, e 73,2 por cem mil n.v. no Nordeste. O fator de ajuste para o conjunto das capitais brasileiras foi igual a 1,4; para as regiões (considerando apenas as capitais, variaram entre 1,08 na Região Norte e 1,83 na Região Sul. As mortes obstétricas diretas corresponderam a 67,1%, mostrando que assistência ao pré-natal, ao parto e ao puerpério deve ser aprimorada.INTRODUCTION: There is criticism as to the heterogeneity and reliability of mortality data in Brazilian Regions. However, official mortality statistics of State Capitals are more accurate and have adequate coverage. Reduction of maternal mortality is one of the world's major goals and it is measured by the Maternal Mortality Ratio. International

  10. THE INFLUENCE OF MANAGERIAL WORK DETERMINANTS ON THE PERCEPTION OF FITNESS BETWEEN TECHNOLOGY AND TASK: AN EXPLORATORY STUDY A INFLUÊNCIA DOS DETERMINANTES DO TRABALHO GERENCIAL NA PERCEPÇÃO DO AJUSTE ENTRE A TECNOLOGIA E A TAREFA: UM ESTUDO EXPLORATÓRIO

    Directory of Open Access Journals (Sweden)

    Mauri Leodir Löbler

    2010-12-01

    Full Text Available This paper investigates if the managerial work nature modifies the manager's perception regarding the adjustment of Information Technology (IT to their task. The indicators of managerial work, as experience and frequency of IT use and manager decision-making roles, were based on studies of Vlahos and Ferrat (1998 and Vlahos, Ferratt and Knoepfle (2004 as well as the task technology fit, reasoned from the Task-Technology Fit model (TTF (Goodhue, 1995. This paper contributes to understanding the IS as a support tool for the tasks that composed the manager's role in the organization. Through an exploratory study conducted with 238 managers, we observed that more increases the experience of the individual with the Information System (IS, greater the adjustment perceived for it, between the technology and the task running; and higher the user access the IS, greater the fit between the technology and their tasks. As for the decision-making roles, we identified the roles of manager/entrepreneur and conflict manager are those who envisage a better adaptation of technology to their work, getting through the IS support for the work to proceed more efficiently. Este artigo investiga se a natureza do trabalho gerencial modifica a percepção do gestor quanto ao ajuste da Tecnologia da Informação (TI à sua tarefa. Os indicadores do trabalho gerencial, como a experiência e frequência de uso da TI e papéis decisórios do gestor, foram baseados nos estudos de Vlahos e Ferrat (1998 e Vlahos, Ferratt e Knoepfle (2004, além do ajuste da tecnologia à tarefa, fundamentado a partir do modelo de Ajuste Tecnologia-Tarefa (TTF (Goodhue, 1995. O trabalho contribui no entendimento dos SI como ferramenta de suporte para a execução das tarefas que compõem o papel do gestor na organização. Através de um estudo exploratório, realizado junto a 238 gestores, observou-se que quanto mais aumenta a experiência do individuo com os Sistemas de Informação (SI, maior

  11. Clinical Trials

    Science.gov (United States)

    Clinical trials are research studies that test how well new medical approaches work in people. Each study answers ... prevent, screen for, diagnose, or treat a disease. Clinical trials may also compare a new treatment to a ...

  12. Clinical Research and Clinical Trials

    Science.gov (United States)

    ... Meetings, Conferences & Events Partnering & Donating to the NICHD Staff Directory ... Clinical Research Skip sharing on social media links Share this: Page Content Clinical research is research that directly involves a ...

  13. Comorbidity adjustment index for the international classification of diseases, 10 Índice de ajuste de co-morbilidad para la 10a revisión de la clasificación internacional de enfermedades Índice de ajuste de comorbidade para a 10a revisão da classificação internacional de doenças

    Directory of Open Access Journals (Sweden)

    Robert Antonio Ramiarina

    2008-08-01

    Full Text Available OBJECTIVE: To develop a Charlson-like comorbidity index based on clinical conditions and weights of the original Charlson comorbidity index. METHODS: Clinical conditions and weights were adapted from the International Classification of Diseases, 10th revision and applied to a single hospital admission diagnosis. The study included 3,733 patients over 18 years of age who were admitted to a public general hospital in the city of Rio de Janeiro, southeast Brazil, between Jan 2001 and Jan 2003. The index distribution was analyzed by gender, type of admission, blood transfusion, intensive care unit admission, age and length of hospital stay. Two logistic regression models were developed to predict in-hospital mortality including: a the aforementioned variables and the risk-adjustment index (full model; and b the risk-adjustment index and patient's age (reduced model. RESULTS: Of all patients analyzed, 22.3% had risk scores >1, and their mortality rate was 4.5% (66.0% of them had scores >1. Except for gender and type of admission, all variables were retained in the logistic regression. The models including the developed risk index had an area under the receiver operating characteristic curve of 0.86 (full model, and 0.76 (reduced model. Each unit increase in the risk score was associated with nearly 50% increase in the odds of in-hospital death. CONCLUSIONS: The risk index developed was able to effectively discriminate the odds of in-hospital death which can be useful when limited information is available from hospital databases.OBJETIVO: Desarrollar un índice de co-morbilidad a partir de las condiciones clínicas y de los pesos de índice original de co-morbilidad de Charlson. MÉTODOS: Las condiciones clínicas y pesos del índice de Charlson fueron adaptados según la Clasificación Internacional de Enfermedades - 10a Revisión, y aplicados al diagnóstico principal de internación hospitalaria. Fueron estudiados 3.733 pacientes arriba de 18 a

  14. Ajuste do modelo de Schumacher e Hall e aplicação de redes neurais artificiais para estimar volume de árvores de eucalipto Adjustment of the Schumacher and Hall model and application of artificial neural networks to estimate volume of eucalypt trees

    OpenAIRE

    Mayra Luiza Marques da Silva; Daniel Henrique Breda Binoti; José Marinaldo Gleriani; Helio Garcia Leite

    2009-01-01

    Objetivou-se, neste trabalho, avaliar o ajuste do modelo volumétrico de Schumacher e Hall por diferentes algoritmos, bem como a aplicação de redes neurais artificiais para estimação do volume de madeira de eucalipto em função do diâmetro a 1,30 m do solo (DAP), da altura total (Ht) e do clone. Foram utilizadas 21 cubagens de povoamentos de clones de eucalipto com DAP variando de 4,5 a 28,3 cm e altura total de 6,6 a 33,8 m, num total de 862 árvores. O modelo volumétrico de Schumacher e Hall f...

  15. Clinical Research

    DEFF Research Database (Denmark)

    Christensen, Irene

    2016-01-01

    This paper is about the logic of problem solving and the production of scientific knowledge through the utilisation of clinical research perspective. Ramp-up effectiveness, productivity, efficiency and organizational excellence are topics that continue to engage research and will continue doing so...... for years to come. This paper seeks to provide insights into ramp-up management studies through providing an agenda for conducting collaborative clinical research and extend this area by proposing how clinical research could be designed and executed in the Ramp- up management setting....

  16. Clinical cases

    International Nuclear Information System (INIS)

    This presentation is about clinical cases and the contribution of the PET - CT Fag application in the diagnosis and treatment of different types of cancer. The cases presented were: neck diseases, epidermoid carcinoma, liver damage and metastasize, lymphoma, thrombosis, colonic cancer and lung disease

  17. Clinical biochemistry

    Science.gov (United States)

    Alexander, W. C.; Leach, C. S.; Fischer, C. L.

    1975-01-01

    The objectives of the biochemical studies conducted for the Apollo program were (1) to provide routine laboratory data for assessment of preflight crew physical status and for postflight comparisons; (2) to detect clinical or pathological abnormalities which might have required remedial action preflight; (3) to discover as early as possible any infectious disease process during the postflight quarantine periods following certain missions; and (4) to obtain fundamental medical knowledge relative to man's adjustment to and return from the space flight environment. The accumulated data presented suggest that these requirements were met by the program described. All changes ascribed to the space flight environment were subtle, whereas clinically significant changes were consistent with infrequent illnesses unrelated to the space flight exposure.

  18. Ajuste dos simuladores de dados meteorológicos do modelo EPIC para diferentes locais do Estado de São Paulo Adjustment of the simulators of meteorological data of the EPIC model for different localities in the State of São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Angélica G. Picini

    2005-06-01

    Full Text Available O modelo EPIC (Erosion Productivity Impact Calculator foi desenvolvido para simular o efeito de estratégias de manejos agrícolas em recursos hídricos e produtividade de solos. No presente estudo, o desempenho dos simuladores de dados meteorológicos foi avaliado para localidades do Estado de São Paulo (Campinas, Jaú, Manduri, Mococa, Pindorama e Ubatuba, incluindo: a Cadeia de Markov para probabilidades de seqüências de dias úmidos e secos; a equação de temperatura máxima ajustada para dias úmidos e a equação de radiação solar, também ajustada para dias úmidos. A partir dos testes e ajustes dos modelos com os dados históricos, verificou-se o melhor desempenho para o modelo de probabilidade de seqüências de dias secos, considerando-se o dia anterior úmido - P(W|D em relação ao modelo de probabilidade de seqüências para dois dias úmidos consecutivos - P(W|W. Os modelos de temperatura máxima do ar e de radiação solar apresentaram bom desempenho nos testes. Para todos os modelos, os melhores resultados foram obtidos a partir dos ajustes para cada local, quando comparados às estimativas obtidas pelos valores originais propostos na concepção do EPIC. Ubatuba apresentou comportamento distinto.EPIC (Erosion Productivity Impact Calculator model has been developed to simulate the effect of agricultural management strategies of water resources and soil productivity. In this study, the performance of meteorological data simulators were evaluated for six (Campinas, Jaú, Manduri, Mococa, Pindorama and Ubatuba localities in the State of São Paulo, Brazil, which include the Markov chain probabilities for the sequences of wet and dry days; the maximum air temperature model adjusted for wet days; and the solar radiation model also adjusted for wet days. From tests and adjustments of the models using the historical data for each locality, the best performance for the model of probabilities for dry days sequence has been found

  19. Influência da função distribuição de quebra na modelagem e simulação do circuito de moagem de Carajás - Parte 1 - ajuste de modelos Influence of the distribution function on modeling and simulation of the Carajás grinding circuit - Part 1 - model fit

    Directory of Open Access Journals (Sweden)

    Bianca Foggiatto

    2010-06-01

    Full Text Available O modelo de misturador perfeito (PMM leva em conta, tanto as características do equipamento, como as do minério. As características do minério são representadas pela função distribuição de quebra. Tal função pode ser determinada através de um método laboratorial proposto pelo JKMRC ou de funções padronizadas. O presente trabalho descreve o processo de modelagem matemática do circuito de moagem de Carajás, utilizando o software JKSimMet. Como resultado, foi possível avaliar a qualidade do ajuste do modelo em dois cenários: 1 utilizando a função distribuição de quebra-padrão do programa; 2 utilizando a função distribuição de quebra determinada para a alimentação do circuito de moagem. A partir desta análise, determinou-se, no ajuste do PMM e, em particular, na função taxa de quebra ou cinética de fragmentação, a influencia da função distribuição.The perfect mixing model (PMM is based on parameters derived from the equipment characteristics as well as ore breakage characteristics. Ore characteristics are represented through the appearance function. This function may be determined using JKMRC laboratorial methods or by standard functions. This work describes the model fitting process of the Carajas grinding circuit, using the JKSimMet simulator. Two scenarios were used in model fitting exercises: 1 standard appearance function; and 2 appearance function based on testing carried out on samples taken at circuit feed. From this assessment, the appearance function's influence in the PMM fit and it's relation with the breakage rate were determined. The influence of the appearance function on the respective breakage rate distribution was assessed.

  20. Clinical arthrography

    Energy Technology Data Exchange (ETDEWEB)

    Arndt, R.; Horns, J.W.; Gold, R.H.; Blaschke, D.D.

    1985-01-01

    This book deals with the method and interpretation of arthrography of the shoulder, knee, ankle, elbow, hip, wrist, and metacarpophalangeal, interphalangeal, and temporomandibular joints. The emphasis is on orthopaedic disorders, usually of traumatic origin, which is in keeping with the application of arthrography in clinical practice. Other conditions, such as inflammatory and degenerative diseases, congenital disorders and, in the case of the hip, arthrography of reconstructive joint surgery, are included. Each chapter is devoted to one joint and provides a comprehensive discussion on the method of arthrography, including single and double contrast techniques where applicable, normal radiographic anatomy, and finally, the interpretation of the normal and the abnormal arthrogram.

  1. Métricas de calidad y un modelo costo : Beneficio ajustados a un caso real de la industria del software

    OpenAIRE

    Sanchez, Alejandro; Riesco, Daniel Eduardo; Montejano, Germán Antonio; Peralta, Mario

    2002-01-01

    Las inspecciones de documentos de software son uno de los métodos más efectivos para detectar defectos, evitando la espera hasta la etapa de pruebas y brindando a la gerencia del proyecto valiosa información en tiempo real. Para analizar la utilización de inspecciones es necesario considerar la evolución de la calidad de los documentos inspeccionados, y la conveniencia económica del proceso. La calidad de los documentos se mide y compara utilizando métricas significativas. La rentabilidad ...

  2. Clinical guidelines.

    Science.gov (United States)

    Uppal, Elaine

    2016-01-01

    This article is part of the Advancing practice series which is aimed at exploring practice issues in more depth, considering topics that are frequently encountered and facilitating the development of new insights. Elaine Uppal focuses on the importance of all midwives developing guideline writing skills to ensure that local, national and international midwifery/maternity guidelines are up to date, relevant and reflect midwifery knowledge alongside 'gold' standard evidence. The article aims to consider the development, use and critical appraisal of clinical guidelines. It will define and explain guidelines; discuss their development and dissemination; and consider issues relating to their use in practice. Techniques to critique and develop guidelines using the AGREE tool will be outlined in the form of practice challenges to be undertaken by the individual or in a group. PMID:26975126

  3. Una Técnica de Inteligencia Artificial para el Ajuste de uno de los Elementos que Definen una B-Spline Racional No Uniforme (NURBS A Technique of Artificial Intelligence to Fit one of the Elements that Define a Non-Uniform Rational B-Spline (NURBS

    Directory of Open Access Journals (Sweden)

    Sandra P Mateus

    2010-01-01

    Full Text Available Dentro de las técnicas existentes de Inteligencia Artificial, se escogieron y adaptaron dos Redes Neuronales Artificiales (RNA para realizar el ajuste de uno de los elementos que definen una B-Spline Racional No Uniforme (NURBS y con ello obtener un modelado adecuado de la NURBS. Los elementos escogidos fueron los puntos de control. Las RNA utilizadas son las de Función de Base Radial y las de Kohonen o Mapas Auto-organizativos. Con base en el análisis de resultados y la caracterización de las RNA, la Función de Base Radial tuvo un desempeño más adecuado y óptimo para un número elevado de datos, lo cual es una desventaja de los Mapas Auto-organizativos. En este modelo se tiene que realizar procesos extras para determinar la neurona ganadora y realizar el reajuste de los pesos.In the existing techniques of Artificial Intelligence, two Artificial Neural Networks (ANN were selected and adapted to fit one of the elements that define a Non-Uniform Rational B-Spline (NURBS and thus obtaining an appropriate modeling of the NURBS. The selected elements were the checkpoints. The ANN used were the Radial Basis Function and the Kohonen model or Self-Organizing Maps. Based on the analysis of the results and characterization of the ANN the Radial Basis Function had a more appropriate and optimum performance for a large number of data, which is a disadvantage of the Self-Organizing Maps. In this model, additional processes must be done to determine the winning neuron and the weights must be refitted.

  4. Rugosidade superficial de uma porcelana feldspática odontológica após simulação de ajuste oclusal e polimento =Surface roughness of a feldspathic dental porcelain after simulation of occlusal adjustment and polishing

    Directory of Open Access Journals (Sweden)

    Werneck, Rafael Dario

    2008-01-01

    Full Text Available Objetivo: O objetivo desse estudo foi avaliar a rugosidade superficial (Ra de uma porcelana feldspática glazeada e submetida a dois sistemas de acabamento e polimento após simulação de ajuste oclusal. Metodologia: Vinte corpos-de-prova de porcelana feldspática glazeada (IPS Classic Ivoclar foram confeccionados em forma de disco de acordo com as recomendações do fabricante e divididos em dois grupos (A e B. A leitura da rugosidade média superficial inicial (Ra 0 foi realizada com um rugosímetro (Surtronic 3+. Os corpos-de-prova foram desgastados com pontas diamantadas (PM82F e 0261PM e a rugosidade superficial foi novamente aferida (Ra 1. O grupo A foi tratado com pontas de acabamento do sistema Edenta (EXA-Cerapol 352 e 362, Cerapol Super 372 e o grupo B com pontas de acabamento de silicone do sistema Tri Hawk (Universal Fase 1 e Fase 2, sendo realizadas novas leituras de rugosidade (Ra 2. Os dados foram analisados por ANOVA e teste de Tukey, ao nível de significância de 0,05. Resultados: Os valores médios de Ra e desvio-padrão (em micrometros foram: Grupo A – Ra 0=0,21±0,07, Ra 1=0,66±0,07, Ra 2=0,23±0,07; e Grupo B – Ra 0=0,20±0,04, Ra 1=0,72±0,06, Ra 2=0,21±0,05. Não houve diferença estatística entre os tratamentos ou entre estes e a porcelana glazeada. Conclusão: Considerando a metodologia empregada, ambos os procedimentos de acabamento e polimento promoveram uma lisura superficial similar à porcelana glazeada original.

  5. Writing clinical scenarios for clinical science questions.

    Science.gov (United States)

    Smith, Phil Em; Mucklow, John C

    2016-04-01

    Written knowledge assessments for physicians in training typically involve multiple-choice questions that use a clinical scenario in a single-best-answer format. The Royal College of Physicians Part 1 MRCP(UK) examination includes basic sciences themes that are challenging to assess through a clinical scenario. A realistic clinical setting based on everyday clinical practice and integral to the question is the clearest demonstration that the knowledge being assessed is clinically relevant. However, without special attention to detail, the scenario in a clinical science question can appear redundant or artificial. Reading unnecessary material frustrates candidates and threatens the reputation of the assessment. In this paper we discuss why a clinical scenario is important for basic science questions and offer advice on setting realistic and plausible clinical scenarios for such questions. PMID:27037383

  6. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... this page please turn Javascript on. Participating in Clinical Trials About Clinical Trials A Research Study With Human Subjects A clinical ... to treat or cure a disease. Phases of Clinical Trials Clinical trials of drugs are usually described based ...

  7. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Participating in Clinical Trials: About Clinical Trials In This Topic About Clinical Trials Risks and Benefits Terms ... with Your Doctor Taking Medicines The information in this topic was provided by the National Library of ...

  8. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Clinical Trials In This Topic About Clinical Trials Risks and Benefits Terms to Know Finding a Clinical ... researchers may gather information about experimental treatments, their risks, and how well they work compare existing therapies ...

  9. Participating in Clinical Trials

    Medline Plus

    Full Text Available Home > Health topics A-Z > Participating in Clinical Trials: About Clinical Trials In This Topic About Clinical Trials Risks ... centers across the country. The National Institutes of Health funds much of this basic research. Screening Trials ...

  10. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Participating in Clinical Trials About Clinical Trials A Research Study With Human Subjects A clinical trial is a research study that involves human subjects. The purpose of ...

  11. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... on. Participating in Clinical Trials About Clinical Trials A Research Study With Human Subjects A clinical trial is a research study that involves human subjects. The purpose ...

  12. Exploring Clinical Overview

    DEFF Research Database (Denmark)

    Fleron, Benedicte

    Clinical overview is explored at four emergency departments (EDs) during the introduction of a new IT system to support hereof. Important aspects of clinical overview are described for the clinical practice and for the further development of the IT system.......Clinical overview is explored at four emergency departments (EDs) during the introduction of a new IT system to support hereof. Important aspects of clinical overview are described for the clinical practice and for the further development of the IT system....

  13. Future requirements. Clinical investigations

    DEFF Research Database (Denmark)

    Qvist, V.

    2002-01-01

    Biocompatability, Cariology, Clinical trials, Dental materials, Helath services research, Human, Pedodontics......Biocompatability, Cariology, Clinical trials, Dental materials, Helath services research, Human, Pedodontics...

  14. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... Research Research Resources Research Meeting Summaries Technology Transfer Clinical Trials What Are Clinical Trials? Children & Clinical Studies NHLBI Trials Clinical Trial Websites ...

  15. Clinical Trials in Vision Research

    Science.gov (United States)

    ... Eye Health Information > Clinical Trials in Vision Research Clinical Trials in Vision Research Listen Clinical studies depend on ... vision research in the United States. Basics of Clinical Trials What is a clinical trial? Clinical trials are ...

  16. Good clinical practice in clinical interventional studies

    OpenAIRE

    Pieterse, Herman; Diamant, Zuzana

    2014-01-01

    Good clinical practice (GCP) guidelines should always be implemented and obeyed in clinical interventional studies. In this mini-review, we will address several burning questions relating to GCP in a concise ‘frequently asked questions’ format.While compliance to current rules and regulations is our mission, we also wish to play devil’s advocate attempting to translate the rules into sizeable chunks using a high dose of common sense.Keywords: clinical interventional studies; quality; safety; ...

  17. Ajuste macro, política monetaria y empleo

    Directory of Open Access Journals (Sweden)

    Jorge Iván González

    2000-04-01

    Full Text Available El artículo muestra que la política monetaria restrictiva ha sido uno de los factores que más ha incidido en el crecimiento del desempleo en Colombia durante la segunda mitad de los años noventa. La tasa de sacrificio de la política monetaria no ha sido cero, porque el costo de reducir la inflación ha sido muy elevado. La responsabilidad que tiene el manejo de la política monetaria en la crisis del sector real se hace más visible si se tiene en cuenta que no hay evidencia de que la menor demanda de trabajo esté asociada a los costos laborales y a las inflexibilidades del mercado laboral.

  18. Procesos de Endeudamiento Externo y Ajuste de Precios

    OpenAIRE

    Hugo Albornoz

    1987-01-01

    The evolution of macroeconomic variables like the real exchange rate, the inflation level, the real interest rate and the change in international reserves is analyzed using a simplified theoretical model during a process in which a country is changing its

  19. Ajuste de redes libres. Modelos matemáticos singulares

    OpenAIRE

    Sevilla, Miguel J.

    2005-01-01

    Corresponde al curso de doctorado "Redes Geodésicas y GPS" impartido dentro del programa "Ciencia y Tecnología de la Ingeniería Geodésica y Cartográfica", de la Facultad de Matemáticas de la Universidad Complutense de Madrid.

  20. Limites: a questão do manejo clínico hoje Limits: the issue of clinical management today

    Directory of Open Access Journals (Sweden)

    Walter Firmo de Oliveira Cruz

    2012-12-01

    Full Text Available Objetiva-se refletir sobre a necessidade de transformação na técnica psicanalítica, considerando o intrapsíquico e o intersubjetivo. A frequência de insucessos nos atendimentos indica a necessidade da discussão de novos parâmetros. A forma de abordar o tema buscou ultrapassar fronteiras entre as escolas psicanalíticas. Procurou-se caracterizar as manifestações subjetivas contemporâneas articulando-as às condições de oferta do trabalho analítico, visando eventuais ajustes no manejo clínico.This article offers a reflection on the need for change in psychoanalytical technique to account for intrapsychic and intersubjective processes. The failure rate in psychotherapeutic practice indicates that new criteria need to be discussed. Approaches to this topic sought to cross borders between different psychoanalytical schools of thought. Contemporary subjective manifestations were characterized and linked with the terms of offer of analytical work to suggest possible changes in clinical management.

  1. Clinical Trial Results: A Clinical Trial Bazaar!

    OpenAIRE

    Fojo, Antonio Tito; Bates, Susan E.

    2014-01-01

    The Oncologist’s Clinical Trial Results section welcomes both positive and negative results in an effort to share information, speed discovery, and inform the field. Clinical Trial Results submissions have shown how succinctly the salient features of a submission can be presented, with more in-depth information to be found online.

  2. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... Children & Clinical Studies NHLBI Trials Clinical Trial Websites Children and Clinical Studies Learn more about Children and Clinical Studies Importance of Children in Clinical Studies Children have often had to ...

  3. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Trials About Clinical Trials A Research Study With Human Subjects A clinical trial is a research study ... lifestyle changes, such as exercising more, getting more sleep, keeping mentally active, or eating nutritious foods, can ...

  4. Clinical Laboratory Fee Schedule

    Data.gov (United States)

    U.S. Department of Health & Human Services — Outpatient clinical laboratory services are paid based on a fee schedule in accordance with Section 1833(h) of the Social Security Act. The clinical laboratory fee...

  5. NIH Clinical Centers

    Data.gov (United States)

    Federal Laboratory Consortium — The NIH Clinical Center consists of two main facilities: The Mark O. Hatfield Clinical Research Center, which opened in 2005, houses inpatient units, day hospitals,...

  6. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... trial is to find out if an experimental drug, therapy, medical device, lifestyle change, or test will ... disease. Phases of Clinical Trials Clinical trials of drugs are usually described based on their phase. The ...

  7. HISTIOCYTOSIS X: CLINICAL OBSERVATIONS

    Directory of Open Access Journals (Sweden)

    E. Y. Ponomareva

    2014-07-01

    Full Text Available Two clinical cases of pulmonary Langerhans cell histiocytosis X have been analyzed demonstrating lung and other inner organ pathology, common clinical and X-ray features but different life prognosis.

  8. HISTIOCYTOSIS X: CLINICAL OBSERVATIONS

    OpenAIRE

    E. Y. Ponomareva; A. P. Rebrov; E. E. Archangelskaja; A. A. Roshchina; R. N. Steshenko; A. S. Bukia; N. V. Dvornikova; N. N. Moskaleva

    2014-01-01

    Two clinical cases of pulmonary Langerhans cell histiocytosis X have been analyzed demonstrating lung and other inner organ pathology, common clinical and X-ray features but different life prognosis.

  9. Research Areas - Clinical Trials

    Science.gov (United States)

    Information about NCI programs and initiatives that sponsor, conduct, develop, or support clinical trials, including NCI’s Clinical Trial Network (NCTN) and NCI Community Oncology Research Program (NCORP) initiatives.

  10. Research Areas: Clinical Trials

    Science.gov (United States)

    Information about NCI programs and initiatives that sponsor, conduct, develop, or support clinical trials, including NCI’s Clinical Trial Network (NCTN) and NCI Community Oncology Research Program (NCORP) initiatives.

  11. Fertility Clinic Success Rates

    Science.gov (United States)

    ... and Autism 2013 Assisted Reproductive Technology Fertility Clinic Success Rates Report Recommend on Facebook Tweet Share Compartir 2013 ART Fertility Clinic Success Rates Report [PDF - 1MB] Bookmarks and thumbnails are ...

  12. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... was provided by the National Library of Medicine Topic last reviewed: December 2013 For an enhanced version of this page please turn Javascript on. Participating in Clinical Trials About Clinical Trials A Research Study With Human Subjects A clinical trial is ...

  13. Evolution of Clinical Enzymology

    OpenAIRE

    Büttner, J

    1981-01-01

    The evolution of clinical enzymology is discussed in relation to the history of general enzymology and clinical chemistry. The discussion is limited to the period from 1835 (definition of catalysis by Berzelius) to 1935 (description of the optical test by Warburg). In conclusion, a general account is given of the introduction of the concept of quantitative enzyme activity determination into clinical medicine.

  14. Clinical Process Intelligence

    DEFF Research Database (Denmark)

    Vilstrup Pedersen, Klaus

    2006-01-01

    Ideally, clinical guidelines are created from evidence based medicine. Translating the narrative semi-structured article for-mat of the clinical guidelines into a computable language makes it possible to utilize this information in IT-supported clinical reasoning, and thereby bring the relevant...

  15. Clinical document architecture.

    Science.gov (United States)

    Heitmann, Kai

    2003-01-01

    The Clinical Document Architecture (CDA), a standard developed by the Health Level Seven organisation (HL7), is an ANSI approved document architecture for exchange of clinical information using XML. A CDA document is comprised of a header with associated vocabularies and a body containing the structural clinical information. PMID:15061557

  16. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... topic was provided by the National Library of Medicine Topic last reviewed: December 2013 For an enhanced version of this page please turn Javascript on. Participating in Clinical Trials About Clinical Trials A Research Study With Human Subjects A clinical trial is a research study ...

  17. Spina Bifida Clinic Directory

    Science.gov (United States)

    ... 798,163.html Back to top Missouri Children’s Mercy Hospital & Clinics Spinal Defects Clinic (pediatric only-will ... 234-3790 or (816) 234 3005 www.childrens-mercy.org/ Cardinal Glennon Children’s Medical Center Myelomeningocele Clinic ( ...

  18. Análise da influência de diferentes tamanhos e composições de amostras no ajuste de uma relação hipsométrica para Eucalyptus grandis Evaluation of the influence of varying sample sizes and composition on the precision of a hypsometric relation for Eucalyptus grandis

    Directory of Open Access Journals (Sweden)

    Gilson Fernandes da Silva

    2007-08-01

    Full Text Available O ajuste de relações hipsométricas a partir de dados oriundos de inventário florestal com o objetivo de estimar o volume de árvores individuais é procedimento comum nas empresas florestais brasileiras. Assim, considerando um conjunto de 481 árvores de Eucalyptus grandis, obtido por meio de um procedimento de inventário florestal, foram simulados diversos tamanhos de amostra, variando de 6 a 204 árvores-amostra. Para cada tamanho de amostra foram feitas 10.000 simulações para cada tamanho de amostra obtidas aleatoriamente. Considerando o exposto, este trabalho teve como objetivo avaliar o efeito do tamanho e da composição das amostras simuladas sobre a precisão de um modelo hipsométrico previamente selecionado. O modelo selecionado teve como variáveis independentes o diâmetro à altura do peito (DAP e a idade, sendo avaliado também o efeito dessas variáveis sobre as estimativas de altura. Ao final, conclui-se que amostras com pelo menos 27 árvores proporcionaram estimativas mais precisas da altura das árvores quando comparadas com amostras menores que esse número. No entanto, amostras maiores que 27 árvores não implicaram ganhos significativos em termos de precisão. Conclui-se também que a variável DAP foi mais importante para estimar a altura do que a variável idade, considerando-se o modelo proposto, sendo a influência da variável idade na estimação da altura maior nas árvores de maior DAP.The adjustment of hypsometric relations using data from forest inventory aiming at the estimation of individual tree volumes is a common task in Brazilian forestry companies. This study used a data set of 481 trees of Eucalyptus grandis from a forest inventory. Simulation was carried out varying sample sizes from 6 to 204 sample-trees. For each sample size it was run 10,000 simulations for each size samples selected randomly. This study aimed at evaluating the effect of sample size and structure on the precision of a

  19. Shoreline changes in Concón and Algarrobo bays, central Chile, using an adjustment model Cambios en la línea litoral de las bahías de Algarrobo y Concón, Chile central, a través de un modelo de ajuste

    Directory of Open Access Journals (Sweden)

    Carolina Martinez

    2007-11-01

    Full Text Available Adjustment models for both Algarrobo and Concón bays, central Chile, are presented herein; the results show a nearly logarithmic spiral shape for the shore. Spatial-temporal variations in the shorelines of both bays were found based on aerial photographs from different years. The results indicate important variations in the relative position of the Concón Bay shoreline between 1945 and 2006, with extreme oscillations (-368 to 123.8 m only occurring in the proximal zone, where the Aconcagua Estuary is located. On the other hand, the spatial-temporal variations in the Algarrobo Bay shoreline between 1967 and 2006 are moderate (131 in the proximal and -73 in the distal zone. Whereas Concón Bay exhibits a stable state of equilibrium for the past 60 years, if the estuary zone is excluded, Algarrobo Bay presents a stable state with a tendency for growth in the proximal zone and retreat in the distal zone. The results are discussed in terms of coastal changes associated with highly urbanized shorelines and applications for coastal area management that are derived from the modelsSe presentan los resultados de la aplicación de un modelo de ajuste para las bahías de Algarrobo y Concón en Chile central, cuya forma se aproxima a una espiral logarítmica. A partir del uso de fotografías aéreas correspondientes a diferentes años, se determinaron las variaciones espacio-temporales de la línea litoral en ambas bahías. Los resultados indican que la bahía de Concón ha presentado importantes variaciones en la posición relativa de su línea litoral para el período 1945 a 2006, únicamente en su zona proximal, lugar en donde se localiza el estuario Aconcagua con oscilaciones extremas entre -368 m y 123,8 m. En la bahía de Algarrobo, las variaciones espacio-temporales de la línea litoral son de magnitud moderada para el período comprendido entre 1967 y 2006, presentando valores extremos de 131 m en la zona proximal y de -73 m en la zona distal

  20. Modelos de ajuste e métodos para a determinação da curva de retenção de água de um Latossolo-vermelho-amarelo Adjustment models and methods for determining the soil water retention curve of a red-yellow Latosol

    Directory of Open Access Journals (Sweden)

    Wanderley Andrade Costa

    2008-04-01

    Full Text Available A caracterização da capacidade de retenção de água de um solo é fundamental para a descrição do fluxo de água através dele e para o adequado manejo da irrigação. São apresentadas comparações entre curvas de retenção de água do solo: ajustadas pelos modelos propostos por van Genuchten e por Hutson & Cass; obtidas pelo método do WP4 usando processo de umedecimento e de secagem; obtidas pelo método da centrífuga utilizando amostras deformadas e indeformadas; e obtidas pelo WP4 e centrífuga, usando um processo de secagem e amostra deformada. Amostras deformadas e indeformadas foram coletadas com trados específicos em um Latossolo Vermelho-Amarelo (LVA, textura argilosa. Foram determinadas as propriedades hídricas do solo necessárias à elaboração das curvas de retenção de água obtidas por análise de regressão. O modelo de van Genuchten possibilitou o melhor ajuste nas diversas situações estudadas. Considerando o processo de secagem, o teor de água útil obtido superou em 13 % o resultado do processo de umedecimento e evidenciou reduzido efeito de histerese. A amostra deformada apresentou-se com um teor de água útil superior 61,7 % ao valor obtido para a amostra indeformada. Entre os métodos estudados, verificou-se que aquele que usa o WP4 subestimou os dados obtidos pela centrífuga. Verificou-se que há diferenças entre amostra deformada e indeformada e os métodos utilizados na obtenção da curva de retenção.The characterization of the soil water retention capacity is fundamental for an adequate irrigation management and water flow description. We present comparisons of soil water retention curves adjusted in distinct ways: by the models proposed by van Genuchten and by Hutson & Cass; by the WP4 method in a wetting and drying process; by the centrifuge method using disturbed as well as undisturbed soil samples; and by the WP4 and centrifuge using a drying process and disturbed soil samples. Disturbed and

  1. Integrating clinical research into clinical decision making

    Directory of Open Access Journals (Sweden)

    Mark R Tonelli

    2011-01-01

    Full Text Available Evidence-based medicine has placed a general priority on knowledge gained from clinical research for clinical decision making. However, knowledge derived from empiric, population-based research, while valued for its ability to limit bias, is not directly applicable to the care of individual patients. The gap between clinical research and individual patient care centers on the fact that empiric research is not generally designed to answer questions of direct relevance to individual patients. Clinicians must utilize other forms of medical knowledge, including pathophysiologic rationale and clinical experience, in order to arrive at the best medical decision for a particular patient. In addition, clinicians must also elucidate and account for the goals and values of individual patients as well as barriers and facilitators of care inherent in the system in which they practice. Evidence-based guidelines and protocols, then, can never be prescriptive. Clinicians must continue to rely on clinical judgment, negotiating potentially conflicting warrants for action, in an effort to arrive at the best decision for a particular patient.

  2. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... NHLBI Trials Clinical Trial Websites Children and Clinical Studies Learn more about Children and Clinical Studies Importance of Children in Clinical Studies Children have often had to accept medicines and ...

  3. Clinical Genomic Database

    OpenAIRE

    Solomon, Benjamin D.; Nguyen, Anh-Dao; Bear, Kelly A.; Wolfsberg, Tyra G.

    2013-01-01

    Technological advances have greatly increased the availability of human genomic sequencing. However, the capacity to analyze genomic data in a clinically meaningful way lags behind the ability to generate such data. To help address this obstacle, we reviewed all conditions with genetic causes and constructed the Clinical Genomic Database (CGD) (http://research.nhgri.nih.gov/CGD/), a searchable, freely Web-accessible database of conditions based on the clinical utility of genetic diagnosis and...

  4. CME ON CLINICAL RESEARCH

    OpenAIRE

    Suneel. I. Majagi; S. S. Torgal; S. V. Hiremath

    2012-01-01

    Safety and efficacy are the two major concerns for any drug therapy. Globally clinical research plays an inevitable role in bringing a new molecule into the market after its synthesis by the pharmaceutical industries. Availability of large patient population, highly educated and skilled manpower, wide spectrum of diseases and favorable economic environment imply India’s potential as a global hub for clinical research. Pharmaceutical companies and Clinical Research Organization (CRO)s will req...

  5. Compliance in clinical trials.

    OpenAIRE

    Pullar, T; Kumar, S; Feely, M

    1989-01-01

    Compliance with treatment can be an important determinant of the outcome of clinical trials. To date there is no completely satisfactory method of measuring compliance and some of the most widely used methods are inadequate. The various methods of measuring compliance and how they have been applied to clinical trials are described, and improvements in the standard of the measurement and reporting of compliance in clinical trials are suggested.

  6. Clinical research informatics

    CERN Document Server

    Richesson, Rachel L

    2012-01-01

    This book provides foundational coverage of key areas, concepts, constructs, and approaches of medical informatics as it applies to clinical research activities, in both current settings and in light of emerging policies. The field of clinical research is fully characterized (in terms of study design and overarching business processes), and there is emphasis on information management aspects and informatics implications (including needed activities) within various clinical research environments. The purpose of the book is to provide an overview of clinical research (types), activities, and are

  7. American Association for Clinical Chemistry

    Science.gov (United States)

    ... indispensable patient care tool. Learn more IN CLINICAL CHEMISTRY ddPCR Quantification of Lymphoma Mutations Researchers have developed ... Online Harmonization.net Commission on Accreditation in Clinical Chemistry American Board of Clinical Chemistry Clinical Chemistry Trainee ...

  8. Clinical decision modeling system

    Directory of Open Access Journals (Sweden)

    Lyons-Weiler James

    2007-08-01

    Full Text Available Abstract Background Decision analysis techniques can be applied in complex situations involving uncertainty and the consideration of multiple objectives. Classical decision modeling techniques require elicitation of too many parameter estimates and their conditional (joint probabilities, and have not therefore been applied to the problem of identifying high-performance, cost-effective combinations of clinical options for diagnosis or treatments where many of the objectives are unknown or even unspecified. Methods We designed a Java-based software resource, the Clinical Decision Modeling System (CDMS, to implement Naïve Decision Modeling, and provide a use case based on published performance evaluation measures of various strategies for breast and lung cancer detection. Because cost estimates for many of the newer methods are not yet available, we assume equal cost. Our use case reveals numerous potentially high-performance combinations of clinical options for the detection of breast and lung cancer. Results Naïve Decision Modeling is a highly practical applied strategy which guides investigators through the process of establishing evidence-based integrative translational clinical research priorities. CDMS is not designed for clinical decision support. Inputs include performance evaluation measures and costs of various clinical options. The software finds trees with expected emergent performance characteristics and average cost per patient that meet stated filtering criteria. Key to the utility of the software is sophisticated graphical elements, including a tree browser, a receiver-operator characteristic surface plot, and a histogram of expected average cost per patient. The analysis pinpoints the potentially most relevant pairs of clinical options ('critical pairs' for which empirical estimates of conditional dependence may be critical. The assumption of independence can be tested with retrospective studies prior to the initiation of

  9. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... In This Topic About Clinical Trials Risks and Benefits Terms to Know Finding a Clinical Trial Informed ... for more information Scientists usually do years of experiments in the laboratory and in animals before they even consider testing an experimental treatment ...

  10. Clinical coding. Code breakers.

    Science.gov (United States)

    Mathieson, Steve

    2005-02-24

    --The advent of payment by results has seen the role of the clinical coder pushed to the fore in England. --Examinations for a clinical coding qualification began in 1999. In 2004, approximately 200 people took the qualification. --Trusts are attracting people to the role by offering training from scratch or through modern apprenticeships. PMID:15768716

  11. Clinical Psychology in Pakistan

    OpenAIRE

    Riffat Moazam Zaman

    1991-01-01

    This article reviews the state of psychology in Pakistan, with special reference to clinical psychology. The issues of statutory recognition, credentials required for practice, public perception of psychology, the practice of indigenous "clinical psychology", sources of payment for psychological services, and relations between psychologists and psychiatrists are reviewed.

  12. Developing Clinical Competence

    NARCIS (Netherlands)

    P.F. Wimmers (Paul)

    2006-01-01

    textabstractThe development of clinical competence is the main purpose of medical education. The long road to become clinically competent starts on the first day of medical school, and every institution strives to select the best students. The responsibility of medical schools is to train th

  13. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... In This Topic About Clinical Trials Risks and Benefits Terms to Know Finding a Clinical Trial Informed ... years of experiments in the laboratory and in animals before they even ... this early research occurs at universities and medical centers across the ...

  14. CLINICAL TRIALS.GOV

    Science.gov (United States)

    ClinicalTrials.gov provides patients, family members, health care professionals, and members of the public easy access to information on clinical trials for a wide range of diseases and conditions. The U.S. National Institutes of Health (NIH), through its National Library of Medi...

  15. Clinical PET application

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Sang-Moo; Hong, S. W.; Choi, C. W.; Yang, S. D.; Choi, J. S.; Kweon, O. J. et al. [Korea Cancer Center Hospital, Seoul (Korea)

    2000-12-01

    PET gives various metabolic images, and is very important, new diagnostic modality in clinical oncology. In Korea Cancer Center Hospital, PET is installed as a research tool of long-mid-term atomic research project. For the efficient use of PET for clinical and research projects, income from the patients should be managed to get the raw material, equipment, manpower, and also for the clinical PET research. 1. Support the clinical application of PET in oncology. 2. Budgetary management of income, costs for raw material, equipment, manpower, and the clinical PET research project. In this year, 1,327 cases of PET images were obtained, which resulted total income of 829,770,000won. Increased demand for {sup 18}FDG in and outside KCCH need more than 2 times production of {sup 18} in a day. Manpower should be added for the second PET operation and RI production. 10 figs., 4 tabs. (Author)

  16. Clinical PET application

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Sang Moo; Hong, Song W.; Choi, Chang W.; Yang, Seong Dae [Korea Cancer Center Hospital, Seoul (Korea)

    1997-12-01

    PET gives various methabolic images, and is very important, new diagnostic modality in clinical oncology. In Korea Cancer Center Hospital, PET is installed as a research tool of long-mid-term atomic research project. For the efficient use of PET for clinical and research projects, income from the patients should be managed to get the raw material, equipment, manpower, and also for the clinical PET research. 1. Support the clinical application of PET in oncology. 2. Budgetary management of income, costs for raw material, equipment, manpower, and the clinical PET research project. In this year, 250 cases of PET images were obtained, which resulted total income of 180,000,000 won. 50,000,000 won was deposited for the 1998 PET clinical research. Second year PET clinical research should be managed under unified project. Increased demand for {sup 18}FDG in and outside KCCH need more than 2 times production of {sup 18}FDG in a day purchase of HPLC pump and {sup 68}Ga pin source which was delayed due to economic crisis, should be done early in 1998. (author). 2 figs., 3 tabs.

  17. Marking out the clinical expert/clinical leader/clinical scholar: perspectives from nurses in the clinical arena

    OpenAIRE

    Mannix, Judy; Wilkes, Lesley; Jackson, Debra

    2013-01-01

    Background Clinical scholarship has been conceptualised and theorised in the nursing literature for over 30 years but no research has captured nurses’ clinicians’ views on how it differs or is the same as clinical expertise and clinical leadership. The aim of this study was to determine clinical nurses’ understanding of the differences and similarities between the clinical expert, clinical leader and clinical scholar. Methods A descriptive interpretative qualitative approach using semi-struct...

  18. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... experimental drug, therapy, medical device, lifestyle change, or test will help treat, find, or prevent a disease. A clinical trial may compare experimental products or tests to those already available or may compare existing ...

  19. Clinical specular microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Hirst, L.W.; Laing, R.A.

    1987-01-01

    This book provides the general ophthalmologist with a guide to the clinical applications of specular microscopy. Important material is included on laser injury, cataract surgery, corneal transplants, glaucoma, uveitis, and trauma.

  20. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... that could identify a disease in its early stages. Usually, trial participants must show signs of the ... Trials Clinical trials of drugs are usually described based on their phase. The U.S. Food and Drug ...

  1. Leprosy neuropathy: clinical presentations.

    Science.gov (United States)

    Nascimento, Osvaldo J M

    2013-09-01

    Leprosy is a chronic infectious peripheral neuropathy caused by Mycobacterium leprae. The different clinical presentations of the disease are determined by the quality of the host immune response. Early detection of leprosy and treatment by multidrug therapy are the most important steps in preventing deformity and disability. Thus the early recognition of the clinical leprosy presentation is essential. Mononeuritis, mononeuritis multiplex (MM), polyneuritis (MM summation) are the most frequent. The frequent anesthetic skin lesions are absent in the pure neuritic leprosy presentation form. Isolated peripheral nerve involvement is common, including the cranial ones. Arthritic presentation is occasionally seen, usually misdiagnosed as rheumatoid arthritis. Attention should be given to autonomic dysfunctions in leprosy. There are clinical presentations with severe neuropathic pain - painful small-fiber neuropathy. Leprous late-onset neuropathy (LLON) clinical presentation should be considered facing a patient who develop an inflammatory neuropathy many years after a previous skin leprosy treatment. PMID:24141500

  2. Clinical Trial Basics

    Science.gov (United States)

    ... Human Services Search the NIH Website NIH Employee Intranet Staff Directory En Español Site Menu Home Health ... am thinking about participating? Xsandra/iStock Risks and benefits Clinical trials involve risks, just as routine medical ...

  3. Fidelity in clinical simulation

    DEFF Research Database (Denmark)

    Jensen, Sanne; Nøhr, Christian; Rasmussen, Stine Loft

    2013-01-01

    Clinical simulation may be used to identify user needs for context sensitive functionalities in e-Health. The objective with this paper is to describe how user requirements and use cases in a large EHR-platform procurement may be validated by clinical simulation using a very low-fidelity prototype...... without any existing test data. Instead of using test scenarios and use cases, the healthcare professionals who are participating in the clinical simulation are generating both scenario and patient data themselves. We found that this approach allows for an imaginative discussion, not restricted by known...... functionalities and limitations, of the ideal EHR-platform. Subsequently, we discuss benefits and challenges of using an extremely low fidelity environment and discuss the degree of fidelity necessary for conducting clinical simulation....

  4. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... was provided by the National Library of Medicine Topic last reviewed: December 2013 For an enhanced version of this page please turn Javascript on. Participating in Clinical Trials ...

  5. Clinical Case Registries (CCR)

    Data.gov (United States)

    Department of Veterans Affairs — The Clinical Case Registries (CCR) replaced the former Immunology Case Registry and the Hepatitis C Case Registry with local and national databases. The CCR:HIV and...

  6. ClinicalTrials.gov

    Data.gov (United States)

    U.S. Department of Health & Human Services — Provides patients, family members, health care professionals, and members of the public easy access to information on clinical trials for a wide range of diseases...

  7. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Learn More Participating in Clinical Trials Videos quiz yourself MedlinePlus for More Information National Institute on Aging Related Topics Talking with Your Doctor Taking Medicines The information in ...

  8. Towards sustainable clinical trials

    OpenAIRE

    Group, Sustainable Trials Study

    2007-01-01

    Currently, few researchers think about the carbon footprint of their trial. The Sustainable Trials Study Group reports that clinical trials are carbon intensive and suggests ways to make them more efficient

  9. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... Clinical Trials Videos quiz yourself MedlinePlus for More Information National Institute on Aging Related Topics Talking with Your Doctor Taking Medicines The information in this topic was provided by the National ...

  10. Consolidated Clinical Microbiology Laboratories

    OpenAIRE

    Sautter, Robert L.; Thomson, Richard B.

    2014-01-01

    The manner in which medical care is reimbursed in the United States has resulted in significant consolidation in the U.S. health care system. One of the consequences of this has been the development of centralized clinical microbiology laboratories that provide services to patients receiving care in multiple off-site, often remote, locations. Microbiology specimens are unique among clinical specimens in that optimal analysis may require the maintenance of viable organisms. Centralized laborat...

  11. Urine in clinical proteomics.

    OpenAIRE

    Decramer, Stéphane; Gonzalez de Peredo, Anne; Breuil, Benjamin; Mischak, Harald; Monsarrat, Bernard; Bascands, Jean-Loup; Schanstra, Joost P

    2008-01-01

    Urine has become one of the most attractive biofluids in clinical proteomics as it can be obtained non-invasively in large quantities and is stable compared with other biofluids. The urinary proteome has been studied by almost any proteomics technology, but mass spectrometry-based urinary protein and peptide profiling has emerged as most suitable for clinical application. After a period of descriptive urinary proteomics the field is moving out of the discovery phase into an era of validation ...

  12. Statistics in clinical practice

    CERN Document Server

    Coggon, David

    2002-01-01

    These days a basic knowledge of statistics is essential for good clinical practice, which presents a daunting challenge to health professionals who are not mathematically inclined. This book is aimed at clinicians and students who view statistics as a necessary evil. It covers the summary and presentation of data as might be required for a clinical meeting, audit or the planning of services, and explains how to interpret the p-values and confidence intervals that are reported in medical and scientific journals.

  13. Clinical careers film.

    Science.gov (United States)

    2015-09-01

    Those interested in developing clinical academic careers might be interested in a short animated film by Health Education England (HEE) and the National Institute for Health Research. The three-minute film, a frame from which is shown below, describes the sort of opportunities that are on offer to all professionals as part of the HEE's clinical academic careers framework. You can view the film on YouTube at tinyurl.com/pelb95c. PMID:26309005

  14. The clinical nanomedicine handbook

    CERN Document Server

    Brenner, Sara

    2013-01-01

    Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provide

  15. Pediatric Anthrax Clinical Management

    OpenAIRE

    Bradley, John S.; Peacock, Georgina; Krug, Steven E.; Bower, William A.; Cohn, Amanda C.; Meaney-Delman, Dana; Pavia, Andrew T.

    2014-01-01

    Anthrax is a zoonotic disease caused by Bacillus anthracis, which has multiple routes of infection in humans, manifesting in different initial presentations of disease. Because B anthracis has the potential to be used as a biological weapon and can rapidly progress to systemic anthrax with high mortality in those who are exposed and untreated, clinical guidance that can be quickly implemented must be in place before any intentional release of the agent. This document provides clinical guidanc...

  16. Clinical Studies with Epothilones

    Science.gov (United States)

    Altmann, Karl-Heinz

    As indicated in previous chapters, epothilone research so far has delivered seven new chemical entities that have been advanced to clinical trials in humans (Fig. 1). However, the amount of clinical data publicly available at this time strongly varies between individual compounds, depending on their development stage, but also on the general publication policy of the developing company. The compound that has been most comprehensively characterized in the clinical literature is ixabepilone (BMS-247550), for which trial results have been described in a number of articles in peer-reviewed journals and which has been granted FDA approval for two clinical indications on Oct. 16, 2007. For all other compounds, most of the information on clinical trials is available only in abstract form. In all these cases it remains uncertain, whether the content of these abstracts fully reflects the content of the subsequent (poster or oral) presentations at the corresponding meeting; in fact, it seems likely that additional data will have been included in the actual meeting presentations that may not have been available at the time of abstract submission. As this is unknown to the author, such additional information cannot be considered in this chapter, which is solely based on information documented in accessible abstracts or journal publications. It should also be kept in mind that the interpretation of data from ongoing clinical trials or forward looking statements based on data from completed trials are always preliminary in character.

  17. Clinical toxinology specialty training.

    Science.gov (United States)

    White, Julian

    2013-07-01

    Clinical toxinology is the medical discipline dealing with the diagnosis, treatment and prevention of toxin diseases caused by exposure to venomous animals and poisonous animals, plants and mushrooms. Currently there is no national or international organisation accrediting or training doctors in this discipline, but the role of the IST in this area is the subject of a recently approved revised Constitution. A few courses covering some aspects of clinical toxinology exist, either with limited curricula, or with only a minor clinical focus, or with a very regional, non-global focus. The only comprehensive clinical toxinology course is the one provided in Adelaide, Australia, running regularly since 1997. This course may form the nucleus from which IST can develop a global accredited training scheme in clinical toxinology. Such a scheme will require input from diverse global regions and will be far more comprehensive and over a much longer time than the current Short Course, though may incorporate the Short Course in some way, or a derivative of it. Accreditation of medical expertise in clinical toxinology will be required at the national level and this might be accomplished by the IST working with existing national medical specialty organisations and governments, with the IST supervising the training and accreditation requirements and the national organisations providing the framework for registration of medical expertise at the local level. PMID:23524067

  18. Fundamentals of clinical trials

    CERN Document Server

    Friedman, Lawrence M; DeMets, David L; Reboussin, David M; Granger, Christopher B

    2015-01-01

    This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise.  Most chapters have been revised considerably from the fourth edition.  A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded.  Many contemporary clinical trial examples have been added.  There is much new material on adverse events, adherence, issues in analysis, electronic data, data sharing, and international trials.  This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of ...

  19. Clinical dosimetry using mosfets

    International Nuclear Information System (INIS)

    Purpose: The use of metal oxide-silicon field effect transistors (MOSFETs) as clinical dosimeters is demonstrated for a number of patients with targets at different clinical sites. Methods and Materials: Commercially available MOSFETs were characterized for energy response, angular dependency of response, and effect of accumulated dose on sensitivity and some inherent properties of MOSFETs. The doses determined both by thermoluminescence dosimetry (TLD) and MOSFETs in clinical situation were evaluated and compared to expected doses determined by calculation. Results: It was observed that a standard calibration of 0.01 Gy/mV gave MOSFET determined doses which agreed with expected doses to within 5% at the 95% confidence limit for photon beams from 6 to 25 MV and electron beams from 5 to 14 MeV. An energy-dependent variation in response of up to 28% was observed between two orientations of a MOSFET. The MOSFET doses compared very well with the doses estimated by TLDs, and the patients tolerated MOSFETs very well. A standard deviation of 3.9% between expected dose and MOSFET determined dose was observed, while for TLDs the standard deviation was 5.1%. The advantages and disadvantages of using MOSFETs for clinical dosimetry are discussed in detail. Conclusion: It was concluded that MOSFETs can be used as clinical dosimeters and can be a good alternative to TLDs. However, they have limitations under certain clinical situations

  20. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... Systematic Evidence Reviews & Clinical Practice Guidelines Resources Continuing Education Researchers Funding Training & Career Development Division of Intramural Research Research Resources Research Meeting Summaries Technology Transfer Clinical Trials What Are Clinical Trials? Children & ...

  1. How Do Clinical Trials Work?

    Science.gov (United States)

    ... Trials Clinical Trial Websites How Do Clinical Trials Work? If you take part in a clinical trial, ... kol). This plan explains how the trial will work. The trial is led by a principal investigator ( ...

  2. Clinical Usefulness of Arbekacin.

    Science.gov (United States)

    Lee, Jae Hoon; Lee, Chang-Seop

    2016-03-01

    Arbekacin is a broad-spectrum aminoglycoside used to treat methicillin-resistant Staphylococcus aureus (MRSA). Arbekacin has antibacterial activities against high-level gentamicin-resistant Enterococci, multidrug-resistant Pseudomonas aeruginosa, and Acinetobacter baumannii et al. Here, we reviewed in vitro data on arbekacin in Staphylococci and Gram-negative microorganisms. We also reviewed clinical studies for clinical efficacy and microbiologic efficacy data in patients with identified MRSA and suspected MRSA infections. The overall clinical efficacy ranged from 66.7% to 89.7%. The microbiologic efficacy rate ranged from 46.2% to 83%. In comparative studies between arbekacin and glycopeptides, arbekacin was similar to other glycopeptides with respect to clinical and microbiological efficacy rates. Combination trials with other antibiotics suggest that arbekacin will be a promising strategy to control Enterococcus spp. multi-drug resistant P. aeruginosa. The major adverse reaction was nephrotoxicity/hepatotoxicity, but patients recovered from most adverse reactions without any severe complications. Based on these results, arbekacin could be a good alternative to vancomycin/teicoplanin in MRSA treatment. Finally, therapeutic drug monitoring is recommended to maximize clinical efficacy and decrease nephrotoxicity. PMID:27104010

  3. La sostenibilidad de la política fiscal en el Perú: 1970-2005

    OpenAIRE

    Luis A. Arias; Elmer Cuba; Raúl Salazar

    1997-01-01

    El presente estudio analiza la historia del déficit fiscal peruano en el período 1970-1996. El estudio tiene dos objetivos. El primero es construir un indicador de la situación fiscal libre de la influencia del ciclo económico; es decir, un déficit macroeconómicamente ajustado (DMA), que permita ver la posición fiscal subyacente. El segundo objetivo es construir indicadores de sostenibilidad fiscal, que puedan ser útiles para prevenir futuros ajustes. Estos ejercicios no solamente son útiles ...

  4. Cinética e modelagem da secagem de carambola (Averrhoa carambola L.) em secador de bandeja = Kinetics and modeling of star fruit (Averrhoa carambola L.) drying in a tray dryer

    OpenAIRE

    Paulo Bonomo; Modesto Antonio Chaves; Rafael da Costa Ilhéu Fontan; Calila Teixeira Santos; Renata Ferreira Bonomo

    2010-01-01

    No presente trabalho, objetivou-se obter curvas de secagem de carambola (Averrhoa carambola L.) em secador de bandejas. A partir dessas curvas foram obtidos dados de taxa de secagem e de difusividade, além do ajuste de modelos semiteóricos aos dados experimentais. As curvas de secagem foram obtidas, utilizando-se um secador de bandejas nas temperaturas de 50, 60 e 70°C e com fluxo de ar de 1,5 m s-1. Aos dados experimentais foram ajustados os modelos dePage, Henderson e Pabis e Exponencial, u...

  5. Estudio comparativo in vitro del aflojamiento de tornillos de fijación en pilares de prótesis implanto asistida

    OpenAIRE

    Tomaghelli, Emanuel Ricardo

    2014-01-01

    El principio que propone Bränemark desde el nacimiento de la implantología es poder montar y desmontar las estructuras protéticas sobre los implantes colocados en los maxilares, gracias al ajuste y/o aflojamiento del tornillo de fijación. El aflojamiento del tornillo del pilar sigue siendo la más frecuentemente reportada en la literatura. El objetivo de este estudio es identificar el aflojamiento de los tornillos de fijación ajustados a 20 y 32 N/cm, y compararlo con experimentos de temperatu...

  6. [Terminology in clinical bioethics].

    Science.gov (United States)

    Herreros, Benjamín; Moreno-Milán, Beatriz; Pacho-Jiménez, Eloy; Real de Asua, Diego; Roa-Castellanos, Ricardo Andrés; Valentia, Emanuele

    2015-01-01

    In this article some of the most relevant terms in clinical bioethics are defined. The terms were chosen based on three criteria: impact on the most important problems in clinical bioethics, difficulty in understanding, and need to clarify their meaning. For a better understanding, the terms were grouped into 5 areas: general concepts (conflict of values, deliberation, conflict of interest, conscientious objection); justice (justice, distributive justice, models of justice, triage); clinical matters (information, competency, capability, informed consent, mature minor, coercion, secrecy, privacy, confidentiality, professional secrecy); end of life (prior instructions, limitation of therapeutic efforts, professional obstinacy, futility, palliative care, palliative sedation, principle of double effect, euthanasia, assisted suicide, persistent vegetative state, minimally conscious state, locked-in syndrome, brain death), and beginning of life (assisted reproduction, genetic counseling, preimplantation genetic diagnosis). PMID:26506495

  7. Clinical pharmacology and malaria.

    Science.gov (United States)

    Breckenridge, A M; Winstanley, P A

    1997-10-01

    The role of clinical pharmacology in improving the prevention and treatment of malaria is reviewed. A series of general and specific issues is discussed, concentrating on risk-benefit and cost-effectiveness. The techniques of clinical pharmacokinetics play an important role in the optimal use of drugs and this is illustrated by studies on quinine and proguanil. In discussing amodiaquine toxicity, the role of the pharmacologist and the chemist in designing out drug toxicity lends hope for producing a new generation of antimalarial drugs. PMID:9625927

  8. CME ON CLINICAL RESEARCH

    Directory of Open Access Journals (Sweden)

    Suneel. I. Majagi

    2012-06-01

    Full Text Available Safety and efficacy are the two major concerns for any drug therapy. Globally clinical research plays an inevitable role in bringing a new molecule into the market after its synthesis by the pharmaceutical industries. Availability of large patient population, highly educated and skilled manpower, wide spectrum of diseases and favorable economic environment imply India’s potential as a global hub for clinical research. Pharmaceutical companies and Clinical Research Organization (CROs will require many trained personnel to carry out the clinical research. Keeping in mind these facts a CME with the theme of “Clinical research” had been jointly organized by the Dept of pharmacology, K.L.E University’s J.N.M.C, Belgaum and Indian Pharmacological Society (I.P.S, Belgaum branch on 20th February 2010. In the first scientific session, Dr.P.A.Patil (JNMC spoke on “Preclinical studies”. In vitro and in vivo experiments of various doses of ‘study drug’ can obtain preliminary efficacy, toxicity and pharmacokinetic information suggesting the scientific merit for further development as an investigational new drug (IND. Local or systemic toxicity studies can be conducted (ex: urine analysis, blood biochemical assay, gross and microscopic pathology etc. Dr. B.J. Mahendra Kumar (KLE University’s College of pharmacy talked on “Role of Drug Controller General of India (DCGI in Clinical Trials”. He explained about Drug and cosmetic acts/rules, requirements/guidelines for permission to import and/or to manufacture new drugs or to undertake clinical trials i.e. Schedule Y and its appendices. Dr.N.M.Patil (JNMC elaborated about “Ethical issues in clinical trials”. Ethics is required to: avoid exploitation of the subjects (maintain safety and wellbeing, protect vulnerable groups, children, disabled, elderly etc. Independent Ethics Committees (IEC and Institutional Review Boards (IRB are concerned with medical ethics. IECs review, regulate

  9. Clinical reasoning of nursing students on clinical placement: Clinical educators' perceptions.

    Science.gov (United States)

    Hunter, Sharyn; Arthur, Carol

    2016-05-01

    Graduate nurses may have knowledge and adequate clinical psychomotor skills however they have been identified as lacking the clinical reasoning skills to deliver safe, effective care suggesting contemporary educational approaches do not always facilitate the development of nursing students' clinical reasoning. While nursing literature explicates the concept of clinical reasoning and develops models that demonstrate clinical reasoning, there is very little published about nursing students and clinical reasoning during clinical placements. Semi-structured interviews were conducted with ten clinical educators to gain an understanding of how they recognised, developed and appraised nursing students' clinical reasoning while on clinical placement. This study found variability in the clinical educators' conceptualisation, recognition, and facilitation of students' clinical reasoning. Although most of the clinical educators conceptualised clinical reasoning as a process those who did not demonstrated the greatest variability in the recognition and facilitation of students' clinical reasoning. The clinical educators in this study also described being unable to adequately appraise a student's clinical reasoning during clinical placement with the use of the current performance assessment tool. PMID:27235568

  10. ClinicalAccess: a clinical decision support tool.

    Science.gov (United States)

    Crowell, Karen; Vardell, Emily

    2015-01-01

    ClinicalAccess is a new clinical decision support tool that uses a question-and-answer format to mirror clinical decision-making strategies. The unique format of ClinicalAccess delivers concise, authoritative answers to more than 120,000 clinical questions. This column presents a review of the product, a sample search, and a comparison with other point-of-care search engines. PMID:25927513

  11. Prolactinomas : clinical studies

    NARCIS (Netherlands)

    Kars, Marleen

    2008-01-01

    Prolactinoma are treated with dopamine agonists, which are effective in reducing prolactin and tumor size. Studies reporting clinical and radiological outcome are scarce. The study described in chapter 2, assesses long-term outcome in patients treated with dopamine agonists for macroprolactinoma. An

  12. The Clinical Supervision Process.

    Science.gov (United States)

    Ramsey, MaryLou

    This document defines clinical supervision as an intensive, interpersonally-focused, one-to-one relationship in which one person is designated to facilitate the development of therapeutic competence in the other person. Ways in which supervision is similar to, and different from, therapy are explained. The following stages in the clinical…

  13. Participating in Clinical Trials

    Medline Plus

    Full Text Available ... to find out if an experimental drug, therapy, medical device, lifestyle change, or test will help treat, find, or prevent a disease. A clinical trial may compare experimental products or ... universities and medical centers across the country. The National Institutes of ...

  14. The Unstructured Clinical Interview

    Science.gov (United States)

    Jones, Karyn Dayle

    2010-01-01

    In mental health, family, and community counseling settings, master's-level counselors engage in unstructured clinical interviewing to develop diagnoses based on the "Diagnostic and Statistical Manual of Mental Disorders" (4th ed., text rev.; "DSM-IV-TR"; American Psychiatric Association, 2000). Although counselors receive education about…

  15. Clinically isolated laryngeal sarcoidosis

    DEFF Research Database (Denmark)

    Plaschke, Christina Caroline; Owen, Hanne Hoejris; Rasmussen, Niels

    2011-01-01

    combination of CO(2)-laser excision of supraglottic tissue and closure of the incision with sutures. All serological tests were negative or normal, including angiotensin 1 converting enzyme. The clinical expression was uniform with pale, smooth swellings of the supraglottic structures. Surgery proved...

  16. Clinical spectrum of onchodermatitis

    International Nuclear Information System (INIS)

    To describe the frequency and to see various dermatological presentations of onchocerciasis in black Africans of Sierra Leone. Local black patients of all age groups, attending dermatology outpatient department of Pak Field Hospital (established as a part of UN peacekeeping mission in Sierra Leone) with clinical diagnosis of onchodermatitis, based on symptomatology and morphological features of the disease, were included. UN troops were excluded. Laboratory investigations including blood complete picture and skin snips were carried out in all patients. Skin biopsy and nodule biopsy was performed in selected cases. Skin manifestations were recorded and categorized into various clinical patterns, i.e. acute, chronic, lichenified, onchocercoma, etc. Data was analyzed by using descriptive statistics in Instat. A total of 3011 patients, belonging to different local tribes, having a variety of skin disorders, were seen during the study period. One hundred and eighty-seven (6.2%) patients were found to have onchodermatitis. Patients were of all ages and both sexes, their ages ranging from 1 month to 73 years. Gender ratio was almost equal. A whole clinical spectrum of onchodermatitis was observed, chronic papular onchodermatitis being the most common pattern. Onchodermatitis with a large spectrum of clinical manifestations was seen in black Africans of the eastern part of Sierra Leone. (author)

  17. Hepatitis C: Clinical Trials

    Science.gov (United States)

    ... Reports Clinician Tools Clinician Tools Home Guidelines and Best Practices Topic Reviews Algorithms, Screens, Toolkits Provider Education Provider ... about federally and privately supported clinical research in human volunteers. Site gives information about a trial's purpose, who may participate, locations, and phone ... Forms State and Local Resources Strat Plan FY 2014-2020 VA Plans, Budget, & ...

  18. Radioimmunoimaging in clinical oncology

    International Nuclear Information System (INIS)

    In the thesis radiolabeled antibodies were tested for screening of cancer in patients without previous knowledge of tumour histopathology. They were tested as well targeting known cancer, sometimes in unknown clinical stage. Methods for detection enhancement utilizing double-tracer techniques and alternative routes of administration were also investigated. (385 refs., 11 tabs.)

  19. Clinical Positioning Space

    DEFF Research Database (Denmark)

    Williams, Lars Peter Hedegaard; Christensen, Mette Krogh; Rytter, Carsten;

    2014-01-01

    In this article, we present a case study of residents’ clinical experiences and communication in outpatient oncology consultations. We apply positioning theory, a dynamic alternative to role theory, to investigate how oncology residents and patients situate themselves as persons with rights and d...

  20. Clinical Mastery of Hypnosis.

    Science.gov (United States)

    Horevitz, Richard P.

    Hypnosis is an increasingly popular clinical intervention. The number of training courses in hypnosis is growing each year. Research on hypnosis training appears to show that limited exposure to training, as is typical in the common 3 to 5 day format of mass training, produces limited results. Only when training is extended over time do the…

  1. OARSI Clinical Trials Recommendations

    DEFF Research Database (Denmark)

    Kraus, V B; Blanco, F J; Englund, M;

    2015-01-01

    The objective of this work was to describe requirements for inclusion of soluble biomarkers in osteoarthritis (OA) clinical trials and progress toward OA-related biomarker qualification. The Guidelines for Biomarkers Working Group, representing experts in the field of OA biomarker research from b...

  2. [Clinical examination of vertigo].

    Science.gov (United States)

    Topka, Helge Roland

    2016-07-01

    Acute vertigo may originate from peripheral or central vestibular disorders. As central vestibular symptoms may indicate severe brainstem or cerebellar ischemia, rapid clinical differentiation is required. To this end, evaluation of spontaneous or gaze-evoked nystagm, head-impulse test as well identification of skew deviation are most helpful. PMID:27464281

  3. Magnesium in Clinical Practice

    OpenAIRE

    E.L. Trisvetova

    1989-01-01

    Magnesium is a macronutrient that is needed for normal body functions. Magnesium deficiency resulting from the influence of exogenous and endogenous factors, is diagnosed by clinical manifestations, resembling the known disease. Magnesium deficiency corrected with the magnesium therapy. Studies show the effectiveness of magnesium orotate for many cardiovascular diseases.

  4. Integrated clinical information system.

    Science.gov (United States)

    Brousseau, G

    1995-01-01

    SIDOCI (Système Informatisé de DOnnées Cliniques Intégrées) is a Canadian joint venture introducing newly-operating paradigms into hospitals. The main goal of SIDOCI is to maintain the quality of care in todayUs tightening economy. SIDOCI is a fully integrated paperless patient-care system which automates and links all information about a patient. Data is available on-line and instantaneously to doctors, nurses, and support staff in the format that best suits their specific requirements. SIDOCI provides a factual and chronological summary of the patient's progress by drawing together clinical information provided by all professionals working with the patient, regardless of their discipline, level of experience, or physical location. It also allows for direct entry of the patient's information at the bedside. Laboratory results, progress notes, patient history and graphs are available instantaneously on screen, eliminating the need for physical file transfers. The system, incorporating a sophisticated clinical information database, an intuitive graphical user interface, and customized screens for each medical discipline, guides the user through standard procedures. Unlike most information systems created for the health care industry, SIDOCI is longitudinal, covering all aspects of the health care process through its link to various vertical systems already in place. A multidisciplinary team has created a clinical dictionary that provides the user with most of the information she would normally use: symptoms, signs, diagnoses, allergies, medications, interventions, etc. This information is structured and displayed in such a manner that health care professionals can document the clinical situation at the touch of a finger. The data is then encoded into the patient's file. Once encoded, the structured data is accessible for research, statistics, education, and quality assurance. This dictionary complies with national and international nomenclatures. It also

  5. Clinical Data Warehousing - A Survey

    DEFF Research Database (Denmark)

    Pedersen, Torben Bach; Jensen, Christian Søndergaard

    1998-01-01

    In this article we present the concept of data warehousing, and its use in the clinical area. Clinical data warehousing will become very important in the near future, as healthcare enterprises need to gain more information from their clinical, administrative, and financial data, in order to impro...... the area, and providing criteria for comparing clinical data warehouse systems....

  6. OARSI Clinical Trials Recommendations

    DEFF Research Database (Denmark)

    McAlindon, T. E.; Driban, J. B.; Henrotin, Y.;

    2015-01-01

    members voted we calculated the median score among the nine members of the working group who completed the score. The document includes 25 recommendations regarding randomization, blocking and stratification, blinding, enhancing accuracy of patient-reported outcomes (PRO), selecting a study population and......The goal of this document is to update the original OARSI recommendations specifically for the design, conduct, and reporting of clinical trials that target symptom or structure modification among individuals with knee osteoarthritis (OA). To develop recommendations for the design, conduct, and...... reporting of clinical trials for knee OA we initially drafted recommendations through an iterative process. Members of the working group included representatives from industry and academia. After the working group members reviewed a final draft, they scored the appropriateness for recommendations. After the...

  7. Clinical ethics and happiness.

    Science.gov (United States)

    Devettere, R J

    1993-02-01

    Most contemporary accounts of clinical ethics do not explain why clinicians should be ethical. Those few that do attempt an explanation usually claim that clinicians should be ethical because ethical behavior provides an important good for the patient--better care. Both these approaches ignore the customary traditional reason for being ethical, namely, the good of the moral agent. This good was commonly called 'happiness'. The following article shows how the personal happiness of the moral agent provided a major reason for being ethical in the ancient philosophical and biblical traditions and how it continues to play a role in the more modern rights-based, Kantian and utilitarian theories. This history suggests that the personal happiness of the clinician, rightly understood, is a legitimate and important goal of clinical ethics. PMID:8433049

  8. Clinical nuclear medicine

    International Nuclear Information System (INIS)

    The importance of nuclear methods within today's medicine derives decisively from the field of diagnostics. Among the clinical treatment possibilities on the whole, therapy with unsealed radioactive sources is for the time being restricted to few diseases. The use of radioactive labeling in biology, biochemistry and, especially, pharmacology and the rest of fundamental medical research does not belong to the actual specialty of nuclear medicine. Nuclear in-vitro diagnostics, which currently account for about two thirds of all activities in nuclear medicine, are largely excluded from this survey, which is mainly restricted to nuclear diagnostics in vivo. This presentation of nuclear diagnostics in vivo is addressed above all to non-specialists who are to be made familiar with the modern methods of clinical nuclear medicine so that these investigation methods could be more effectively used in future both with qualitative and quantitative regards. (orig./MG)

  9. Clinical Relevance of Adipokines

    Directory of Open Access Journals (Sweden)

    Matthias Blüher

    2012-10-01

    Full Text Available The incidence of obesity has increased dramatically during recent decades. Obesity increases the risk for metabolic and cardiovascular diseases and may therefore contribute to premature death. With increasing fat mass, secretion of adipose tissue derived bioactive molecules (adipokines changes towards a pro-inflammatory, diabetogenic and atherogenic pattern. Adipokines are involved in the regulation of appetite and satiety, energy expenditure, activity, endothelial function, hemostasis, blood pressure, insulin sensitivity, energy metabolism in insulin sensitive tissues, adipogenesis, fat distribution and insulin secretion in pancreatic β-cells. Therefore, adipokines are clinically relevant as biomarkers for fat distribution, adipose tissue function, liver fat content, insulin sensitivity, chronic inflammation and have the potential for future pharmacological treatment strategies for obesity and its related diseases. This review focuses on the clinical relevance of selected adipokines as markers or predictors of obesity related diseases and as potential therapeutic tools or targets in metabolic and cardiovascular diseases.

  10. Clinical Applications for Estetrol

    Directory of Open Access Journals (Sweden)

    Visser M

    2010-01-01

    Full Text Available In this paper the potential clinical applications for the human fetal estrogen estetrol (E4 are presented based on recently obtained data in preclinical and clinical studies. In the past E4 has been classified as a weak estrogen due to its rather low estrogen receptor affinity. However, recent research has demonstrated that due to its favorable pharmacokinetic properties, especially the slow elimination and long half-life, E4 is an effective orally bioavailable estrogen agonist with estrogen antagonistic effects on the breast in the presence of estradiol. Based on the pharmacokinetic properties, the pharmacological profile and the safety and efficacy results in human studies, E4 seems potentially suitable as a drug for human use in applications such as hormone replacement therapy (vaginal atrophy and vasomotor symptoms, contraception, osteoporosis and breast cancer.

  11. Clinical physiopathology of hypernatremia

    Directory of Open Access Journals (Sweden)

    F. Sgambato

    2013-05-01

    Full Text Available BACKGROUND The maintenance of sodium levels at normal ranges has to be considered one of the most important and crucial physiological balance in order to preserve life. The increase of natremia determines the leakage of H2O from the inside of cells and the consequent brain cells withering, that causes encephalopathy at different stages and in some cases it can even lead to death. AIM OF THE STUDY The fundamentals of general physiopathology are analysed together with systems of compensation and brain adaptation in the three different aetiopathogenetic forms: primary increase of sodium (hypervolemic and haedematose form; missed introduction of pure water (mainly euvolemic form, with no aedema; loss of hypotonic fluids (hypovolemic form with dehydration. The three different clinical entities with their relative clinical approaches have been described.

  12. Prolactinomas: clinical studies

    OpenAIRE

    Kars, Marleen

    2008-01-01

    Prolactinoma are treated with dopamine agonists, which are effective in reducing prolactin and tumor size. Studies reporting clinical and radiological outcome are scarce. The study described in chapter 2, assesses long-term outcome in patients treated with dopamine agonists for macroprolactinoma. An increased risk of cardiac valve disease has been reported in patients treated with cabergoline for Parkinson’s disease. Stimulation of serotonin receptors on cardiac valves by dopamine agonists re...

  13. Clinical multiphoton FLIM tomography

    Science.gov (United States)

    König, Karsten

    2012-03-01

    This paper gives an overview on current clinical high resolution multiphoton fluorescence lifetime imaging in volunteers and patients. Fluorescence lifetime imaging (FLIM) in Life Sciences was introduced in Jena/Germany in 1988/89 based on a ZEISS confocal picosecond dye laser scanning microscope equipped with a single photon counting unit. The porphyrin distribution in living cells and living tumor-bearing mice was studied with high spatial, temporal, and spectral resolution. Ten years later, time-gated cameras were employed to detect dental caries in volunteers based on one-photon excitation of autofluorescent bacteria with long fluorescence lifetimes. Nowadays, one-photon FLIM based on picosecond VIS laser diodes are used to study ocular diseases in humans. Already one decade ago, first clinical twophoton FLIM images in humans were taken with the certified clinical multiphoton femtosecond laser tomograph DermaInspectTM. Multiphoton tomographs with FLIM modules are now operating in hospitals at Brisbane, Tokyo, Berlin, Paris, London, Modena and other European cities. Multiple FLIM detectors allow spectral FLIM with a temporal resolution down to 20 ps (MCP) / 250 ps (PMT) and a spectral resolution of 10 nm. Major FLIM applications include the detection of intradermal sunscreen and tattoo nanoparticles, the detection of different melanin types, the early diagnosis of dermatitis and malignant melanoma, as well as the measurement of therapeutic effects in pateints suffering from dermatitis. So far, more than 1,000 patients and volunteers have been investigated with the clinical multiphoton FLIM tomographs DermaInspectTM and MPTflexTM.

  14. Rural health clinics infrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Olson, K.

    1997-12-01

    The author discusses programs which were directed at the installation of photovoltaic power systems in rural health clinics. The objectives included: vaccine refrigeration; ice pack freezing; lighting; communications; medical appliances; sterilization; water purification; and income generation. The paper discusses two case histories, one in the Dominican Republic and one in Colombia. The author summarizes the results of the programs, both successes and failures, and offers an array of conclusions with regard to the implementation of future programs of this general nature.

  15. Dabigatran in clinical practice

    DEFF Research Database (Denmark)

    Ageno, Walter; Eikelboom, John; Lip, Gregory Y H

    2016-01-01

    confirmed, but VKA use is complicated by need for regular monitoring of the international normalized ratio and multiple drug and food interactions. Dabigatran is an oral direct thrombin inhibitor that can be used with fixed doses, without the need for routine anticoagulation laboratory monitoring and the...... agent for dabigatran has been approved by FDA and EU. This review provides a summary of publications assessing clinical utility of dabigatran for different indications....

  16. Horizons in clinical nanomedicine

    CERN Document Server

    Karagkiozaki, Varvara

    2014-01-01

    Nanomedicine-the application of nanotechnology to health sciences-has the potential to address many important medical problems by exploiting the advanced physicochemical characteristics of nanostructured materials and devices. It can revolutionize conventional medicine by offering cutting-edge developments in the processes of diagnosing, treating, and preventing diseases, injuries, or genetic disorders. Thus, clinical nanomedicine holds promise to preserve and improve human health.This book provides a comprehensive overview on the forefront developments of nanotechnology in various domains of

  17. Pharmacovigilance using Clinical Text.

    Science.gov (United States)

    Lependu, Paea; Iyer, Srinivasan V; Bauer-Mehren, Anna; Harpaz, Rave; Ghebremariam, Yohannes T; Cooke, John P; Shah, Nigam H

    2013-01-01

    The current state of the art in post-marketing drug surveillance utilizes voluntarily submitted reports of suspected adverse drug reactions. We present data mining methods that transform unstructured patient notes taken by doctors, nurses and other clinicians into a de-identified, temporally ordered, patient-feature matrix using standardized medical terminologies. We demonstrate how to use the resulting high-throughput data to monitor for adverse drug events based on the clinical notes in the EHR. PMID:24303315

  18. Psychiatrists and clinical psychologists

    Directory of Open Access Journals (Sweden)

    Ajai R. Singh

    2006-03-01

    Full Text Available Psychiatrists and clinical psychologists share an inevitable, if rather uneasy, relationship. So very much like a modern marriage. Can't do without it, can't get out of it. Both sides contemplate divorce often. Think of separation by mutual consent. Even keep threatening as they rave and rant. Have secret, and not so secret, flings on the side. But, like the proverbial homing bird, or the conservative Indian arranged marriage, have no option but to stick it out with each other. Psychiatrists are otherwise good people. But that does not make them immune to handling clinical psychologists with the condescending tolerance and patronizing acceptance that teachers, for example, have towards rambling students. Or the rich have towards the poor. This does not take long to get converted into exasperation and smirky asides in the less charitable amongst the psychiatrists. Not that clinical psychologists are very helpful in motivating the psychiatrists to change for the better. For they, like most people in their position, over react and get aggressive when confronted with this attitude. And understandably so. However, it is time both realized their attitudes were not helpful either for mutual interaction, or growth of the Mental Health Movement at large. We can understand why psychiatrists behave the way they do. They are exposed to this same condescending-patronising attitude from their own peers in the medical profession. Their medical colleagues have yet to develop a feeling of healthy respect for psychiatry. Psychiatrists, no doubt, feel this is unjustified, but their peers are still in a position to deny them the respect and acceptance they seek. What they get from their medical colleagues, they unwittingly pass on to their clinical psychologist colleagues. But understanding why it occurs does not absolve them of their responsibility to behave more rationally, rather than emotionally, with the latter. [No abstract available.

  19. Clinical Applications of Capnography

    OpenAIRE

    NIKOLOVA-TODOROVA, ZORICA

    2008-01-01

    This article gives a short review of the basic definitions of capnography and its use. The introduction gives an overview of the historical development of this procedure. Technical features of the method are presented, followed by several definitions for understanding the basic terms needed to realize the applications of capnography. The last section is a descriptive part that explains the most important clinical applications of capnography, the strengths and limitations of this method. This ...

  20. Randomised clinical trial

    DEFF Research Database (Denmark)

    Meineche-Schmidt, V.; Christensen, E.; Bytzer, P.

    2011-01-01

    Background: Response to proton pump inhibitor (PPI) treatment in dyspepsia is unpredictable. Aim: To identify symptoms associated with response to esomeprazole in order to target patients for empirical treatment. Methods: Eight hundred and five uninvestigated, primary care patients with upper GI ....... Conclusions In patients with uninvestigated dyspepsia, PPI responders can be reliably identified by a simple pocket chart using symptoms and patient characteristics (ClinicalTrials.gov NCT00318968). © 2010 Blackwell Publishing Ltd....

  1. Clinical vaccine development

    OpenAIRE

    Han, Seunghoon

    2015-01-01

    Vaccination is regarded as one of the biggest triumphs in the history of medicine. We are living in the most successful period of vaccine development. The accumulation of multidisciplinary knowledge and the investment of massive funding have enabled the development of vaccines against many infectious diseases as well as other diseases including malignant tumors. The paradigm of clinical vaccine evaluation and licensure has also been modernized based on scientific improvements and historical e...

  2. Hyponatraemia in clinical practice

    OpenAIRE

    Biswas, M.; Davies, J S

    2007-01-01

    Hyponatraemia is defined as a serum sodium concentration below 135 mmol/l. It causes major diagnostic and management problems in practice. Hyponatraemic disorders are divided into euvolaemic, hypervolaemic and hypovolaemic. In the evaluation of the hyponatraemic patient, history taking should focus on identifying the potential cause, duration and symptomatology. Clinical examination should include assessment of volume status. Acute hyponatraemia of less than 48 h duration requires prompt corr...

  3. STRUCTURED CLINICAL EVALUATION

    Directory of Open Access Journals (Sweden)

    Arabela Maria Barbosa Sampaio

    2014-05-01

    Full Text Available In a world experiencing profound technological and socio-political changes in areas of knowledge and capacity, healthcare can not remain static. A new kind of professional is required, whose practice is based on ethics, scientific standards, integrity, citizenship, and health promotion, who develops skills beyond healthcare, such as decision making, communication,leadership, management, and continuing education. No single method can assess all of these elements (knowledge, skills, and attitudes, and only a combination of methods is able to produce a valid evaluation. An alternative method exists: structured clinical assessments based on observation of "to do, or how to do" that aim to complete this evaluation by focusing attention on the performance of specific skills. In order to broaden the scope of evaluation methods that have been used in health education, this article, a literature review, intends to offer readers an overview of the diverse types of structured clinical evaluation, emphasizing Objective Structured Clinical Examination, the most widely used in Brazil, with a goal of advancing opportunities for health professionals to make use of this evaluative tool.

  4. Gateways to clinical trials.

    Science.gov (United States)

    Bayes, M; Rabasseda, X; Prous, J R

    2002-01-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses, which has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the world's first drug discovery and development portal, providing information on study design, treatments, conclusions and references. This issue focuses on the following selection of drugs: Abacavir sulfate; abciximab; abetimus sodium; adalimumab; aldesleukin; almotriptan; alteplase; amisulpride; amitriptyline hydrochloride; amoxicillin trihydrate; atenolol; atorvastatin calcium; atrasentan; Beclometasone dipropionate; bosentan; Captopril; ceftriaxone sodium; cerivastatin sodium; cetirizine hydrochloride; cisplatin; citalopram hydrobromide; Dalteparin sodium; darusentan; desirudin; digoxin; Efalizumab; enoxaparin sodium; ertapenem sodium; esomeprazole magnesium; estradiol; ezetimibe; Famotidine; farglitazar; fluorouracil; fluticasone propionate; fosamprenavir sodium; Glibenclamide; glucosamine sulfate; Heparin sodium; HSPPC-96; hydrochlorothiazide; Imatinib mesilate; implitapide; Lamivudine; lansoprazole; lisinopril; losartan potassium; l-Propionylcarnitine; Melagatran; metformin hydrochloride; methotrexate; methylsulfinylwarfarin; Nateglinide; norethisterone; Olmesartan medoxomil; omalizumab; omapatrilat; omeprazole; oseltamivir phosphate; oxatomide; Pantoprazole; piperacillin sodium; pravastatin sodium; Quetiapine hydrochloride; Rabeprazole sodium; raloxifene hydrochloride; ramosetron hydrochloride; ranolazine; rasburicase; reboxetine mesilate; recombinant somatropin; repaglinide; reteplase; rosiglitazone; rosiglitazone maleate; rosuvastatin calcium; Sertraline; simvastatin; sumatriptan succinate; Tazobactam sodium; tenecteplase; tibolone; tinidazole; tolterodine tartrate; troglitazone; Uniprost; Warfarin sodium; Ximelagatran. PMID:11980386

  5. Myocarditis in Clinical Practice.

    Science.gov (United States)

    Sinagra, Gianfranco; Anzini, Marco; Pereira, Naveen L; Bussani, Rossana; Finocchiaro, Gherardo; Bartunek, Jozef; Merlo, Marco

    2016-09-01

    Myocarditis is a polymorphic disease characterized by great variability in clinical presentation and evolution. Patients presenting with severe left ventricular dysfunction and life-threatening arrhythmias represent a demanding challenge for the clinician. Modern techniques of cardiovascular imaging and the exhaustive molecular evaluation of the myocardium with endomyocardial biopsy have provided valuable insight into the pathophysiology of this disease, and several clinical registries have unraveled the disease's long-term evolution and prognosis. However, uncertainties persist in crucial practical issues in the management of patients. This article critically reviews current information for evidence-based management, offering a rational and practical approach to patients with myocarditis. For this review, we searched the PubMed and MEDLINE databases for articles published from January 1, 1980, through December 31, 2015, using the following terms: myocarditis, inflammatory cardiomyopathy, and endomyocardial biopsy. Articles were selected for inclusion if they represented primary data or were review articles published in high-impact journals. In particular, a risk-oriented approach is proposed. The different patterns of presentation of myocarditis are classified as low-, intermediate-, and high-risk syndromes according to the most recent evidence on prognosis, clinical findings, and both invasive and noninvasive testing, and appropriate management strategies are proposed for each risk class. PMID:27489051

  6. Basic and clinical immunology

    Science.gov (United States)

    Chinen, Javier; Shearer, William T.

    2003-01-01

    Progress in immunology continues to grow exponentially every year. New applications of this knowledge are being developed for a broad range of clinical conditions. Conversely, the study of primary and secondary immunodeficiencies is helping to elucidate the intricate mechanisms of the immune system. We have selected a few of the most significant contributions to the fields of basic and clinical immunology published between October 2001 and October 2002. Our choice of topics in basic immunology included the description of T-bet as a determinant factor for T(H)1 differentiation, the role of the activation-induced cytosine deaminase gene in B-cell development, the characterization of CD4(+)CD25(+) regulatory T cells, and the use of dynamic imaging to study MHC class II transport and T-cell and dendritic cell membrane interactions. Articles related to clinical immunology that were selected for review include the description of immunodeficiency caused by caspase 8 deficiency; a case series report on X-linked agammaglobulinemia; the mechanism of action, efficacy, and complications of intravenous immunoglobulin; mechanisms of autoimmunity diseases; and advances in HIV pathogenesis and vaccine development. We also reviewed two articles that explore the possible alterations of the immune system caused by spaceflights, a new field with increasing importance as human space expeditions become a reality in the 21st century.

  7. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... E-Newsletters About NHLBI Organization NHLBI Director Budget, Planning, & Legislative Advisory ... Learn more about Children and Clinical Studies Importance of Children in Clinical Studies Children have often ...

  8. Clinical Assay Development Support - Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    The NCI’s Division of Cancer Treatment and Diagnosis and the Cancer Diagnosis Program announce a request for applications for the Clinical Assay Development Program (CADP) for investigators seeking clinical assay development and validation resources.

  9. Construction of ethics in clinical research: clinical trials registration

    Directory of Open Access Journals (Sweden)

    C. A. Caramori

    2007-01-01

    Full Text Available Scientific development that has been achieved through decades finds in clinical research a great possibility of translating findings to human health application. Evidence given by clinical trials allows everyone to have access to the best health services. However, the millionaire world of pharmaceutical industries has stained clinical research with doubt and improbability. Study results (fruits of controlled clinical trials and scientific publications (selective, manipulated and with wrong conclusions led to an inappropriate clinical practice, favoring the involved economic aspect. In 2005, the International Committee of Medical Journal Editors (ICMJE, supported by the World Association of Medical Editors, started demanding as a requisite for publication that all clinical trials be registered at the database ClinicalTrials.gov. In 2006, the World Health Organization (WHO created the International Clinical Trial Registry Platform (ICTRP, which gathers several registry centers from all over the world, and required that all researchers and pharmaceutical industries register clinical trials. Such obligatory registration has progressed and will extend to all scientific journals indexed in all worldwide databases. Registration of clinical trials means another step of clinical research towards transparency, ethics and impartiality, resulting in real evidence to the forthcoming changes in clinical practice as well as in the health situation.

  10. Philosophy of clinical psychopharmacology.

    Science.gov (United States)

    Aragona, Massimiliano

    2013-03-01

    The renewal of the philosophical debate in psychiatry is one exciting news of recent years. However, its use in psychopharmacology may be problematic, ranging from self-confinement into the realm of values (which leaves the evidence-based domain unchallenged) to complete rejection of scientific evidence. In this paper philosophy is conceived as a conceptual audit of clinical psychopharmacology. Its function is to criticise the epistemological and methodological problems of current neopositivist, ingenuously realist and evidence-servant psychiatry from within the scientific stance and with the aim of aiding psychopharmacologists in practicing a more self-aware, critical and possibly useful clinical practice. Three examples are discussed to suggest that psychopharmacological practice needs conceptual clarification. At the diagnostic level it is shown that the crisis of the current diagnostic system and the problem of comorbidity strongly influence psychopharmacological results, new conceptualizations more respondent to the psychopharmacological requirements being needed. Heterogeneity of research samples, lack of specificity of psychotropic drugs, difficult generalizability of results, need of a phenomenological study of drug-induced psychopathological changes are discussed herein. At the methodological level the merits and limits of evidence-based practice are considered, arguing that clinicians should know the best available evidence but that guidelines should not be constrictive (due to several methodological biases and rhetorical tricks of which the clinician should be aware, sometimes respondent to extra-scientific, economical requests). At the epistemological level it is shown that the clinical stance is shaped by implicit philosophical beliefs about the mind/body problem (reductionism, dualism, interactionism, pragmatism), and that philosophy can aid physicians to be more aware of their beliefs in order to choose the most useful view and to practice coherently

  11. Gateways to clinical trials.

    Science.gov (United States)

    Bayés, M; Rabasseda, X; Prous, J R

    2005-04-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity. prous.com. This issue focuses on the following selection of drugs: ABX-IL-8, Acclaim, adalimumab, AGI-1067, alagebrium chloride, alemtuzumab, Alequel, Androgel, anti-IL-12 MAb, AOD-9604, aripiprazole, atomoxetine hydrochloride; Biphasic insulin aspart, bosentan, botulinum toxin type B, bovine lactoferrin, brivudine; Cantuzumab mertansine, CB-1954, CDB-4124, CEA-TRICOM, choriogonadotropin alfa, cilansetron, CpG-10101, CpG-7909, CTL-102, CTL-102/CB-1954; DAC:GRF, darbepoetin alfa, davanat-1, decitabine, del-1 Genemedicine, dexanabinol, dextofisopam, dnaJP1, dronedarone hydrochloride, dutasteride; Ecogramostim, eletriptan, emtricitabine, EPI-hNE-4, eplerenone, eplivanserin fumarate, erlotinib hydrochloride, ertapenem sodium, escitalopram oxalate, esomeprazole magnesium, etoricoxib, ezetimibe; Falecalcitriol, fingolimod hydrochloride; Gepirone hydrochloride; HBV-ISS, HSV-2 theracine, human insulin; Imatinib mesylate, Indiplon, insulin glargine, ISAtx-247; L612 HuMAb, levodopa/carbidopa/entacapone, lidocaine/prilocaine, LL-2113AD, lucinactant, LY-156735; Meclinertant, metelimumab, morphine hydrochloride, morphine-6-glucuronide; Natalizumab, nimotuzumab, NX-1207, NYVAC-HIV C; Omalizumab, onercept, osanetant; PABA, palosuran sulfate, parathyroid hormone (human recombinant), parecoxib sodium, PBI-1402, PCK-3145, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b/ribavirin, pemetrexed disodium, pimecrolimus, PINC, pregabalin; Ramelteon, rasagiline mesilate, rasburicase, rimonabant hydrochloride, RO-0098557, rofecoxib, rosiglitazone maleate/metformin hydrochloride; Safinamide mesilate, SHL-749, sitaxsentan sodium, sparfosic acid, SprayGel, squalamine, St. John's Wort

  12. Shared clinical decision making

    Science.gov (United States)

    AlHaqwi, Ali I.; AlDrees, Turki M.; AlRumayyan, Ahmad; AlFarhan, Ali I.; Alotaibi, Sultan S.; AlKhashan, Hesham I.; Badri, Motasim

    2015-01-01

    Objectives: To determine preferences of patients regarding their involvement in the clinical decision making process and the related factors in Saudi Arabia. Methods: This cross-sectional study was conducted in a major family practice center in King Abdulaziz Medical City, Riyadh, Saudi Arabia, between March and May 2012. Multivariate multinomial regression models were fitted to identify factors associated with patients preferences. Results: The study included 236 participants. The most preferred decision-making style was shared decision-making (57%), followed by paternalistic (28%), and informed consumerism (14%). The preference for shared clinical decision making was significantly higher among male patients and those with higher level of education, whereas paternalism was significantly higher among older patients and those with chronic health conditions, and consumerism was significantly higher in younger age groups. In multivariate multinomial regression analysis, compared with the shared group, the consumerism group were more likely to be female [adjusted odds ratio (AOR) =2.87, 95% confidence interval [CI] 1.31-6.27, p=0.008] and non-dyslipidemic (AOR=2.90, 95% CI: 1.03-8.09, p=0.04), and the paternalism group were more likely to be older (AOR=1.03, 95% CI: 1.01-1.05, p=0.04), and female (AOR=2.47, 95% CI: 1.32-4.06, p=0.008). Conclusion: Preferences of patients for involvement in the clinical decision-making varied considerably. In our setting, underlying factors that influence these preferences identified in this study should be considered and tailored individually to achieve optimal treatment outcomes. PMID:26620990

  13. Gateways to clinical trials.

    Science.gov (United States)

    Tomillero, A; Moral, M A

    2010-11-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Thomson Reuters Integrity(SM), the drug discovery and development portal, http://www.thomsonreutersintegrity.com. This issue focuses on the following selection of drugs: Abatacept, Adalimumab, AdCD40L, Adefovir, Aleglitazar, Aliskiren fumarate, AM-103, Aminolevulinic acid methyl ester, Amlodipine, Anakinra, Aprepitant, Aripiprazole, Atazanavir sulfate, Axitinib; Belimumab, Bevacizumab, Bimatoprost, Bortezomib, Bupropion/naltrexone; Calcipotriol/betamethasone dipropionate, Certolizumab pegol, Ciclesonide, CYT-997; Darbepoetin alfa, Darunavir, Dasatinib, Desvenlafaxine succinate, Dexmethylphenidate hydrochloride cogramostim; Eltrombopag olamine, Emtricitabine, Escitalopram oxalate, Eslicarbazepine acetate, Eszopiclone, Etravirine, Everolimus-eluting coronary stent, Exenatide, Ezetimibe; Fenretinide, Filibuvir, Fludarabine; Golimumab; Hepatitis B hyperimmunoglobulin, HEV-239, HP-802-247, HPV-16/18 AS04, HPV-6/11/16/18, Human albumin, Human gammaglobulin; Imatinib mesylate, Inotuzumab ozogamicin, Invaplex 50 vaccine; Lapatinib ditosylate, Lenalidomide, Liposomal doxorubicin, Lopinavir, Lumiliximab, LY-686017; Maraviroc, Mecasermin rinfabate; Narlaprevir; Ocrelizumab, Oral insulin, Oritavancin, Oxycodone hydrochloride/naloxone; Paclitaxel-eluting stent, Palonosetron hydrochloride, PAN-811, Paroxetine, Pazopanib hydrochloride, Peginterferon alfa-2a, Peginterferon alfa-2b, Pemetrexed disodium, Pertuzumab, Pitavastatin calcium, Posaconazole, Pregabalin, Prucalopride succinate; Raltegravir potassium, Ranibizumab, RHAMM R3 peptide, Rosuvastatin calcium; Salclobuzic acid sodium salt, SCY-635, Selenate sodium, Semapimod hydrochloride, Silodosin, Siltuximab, Silybin, Sirolimus-eluting stent, SIR-Spheres, Sunitinib malate; Tapentadol hydrochloride, Tenofovir disoproxil

  14. Classification and clinical assessment

    Directory of Open Access Journals (Sweden)

    F. Cantini

    2012-06-01

    Full Text Available There are at least nine classification criteria for psoriatic arthritis (PsA that have been proposed and used in clinical studies. With the exception of the ESSG and Bennett rules, all of the other criteria sets have a good performance in identifying PsA patients. As the CASPAR criteria are based on a robust study methodology, they are considered the current reference standard. However, if there seems to be no doubt that they are very good to classify PsA patients (very high specificity, they might be not sensitive enough to diagnose patients with unknown early PsA. The vast clinical heterogeneity of PsA makes its assessment very challenging. Peripheral joint involvement is measured by 78/76 joint counts, spine involvement by the instruments used for ankylosing spondylitis (AS, dactylitis by involved digit count or by the Leeds dactylitis index, enthesitis by the number of affected entheses (several indices available and psoriasis by the Psoriasis Area and Severity Index (PASI. Peripheral joint damage can be assessed by a modified van der Heijde-Sharp scoring system and axial damage by the methods used for AS or by the Psoriatic Arthritis Spondylitis Radiology Index (PASRI. As in other arthritides, global evaluation of disease activity and severity by patient and physician and assessment of disability and quality of life are widely used. Finally, composite indices that capture several clinical manifestations of PsA have been proposed and a new instrument, the Psoriatic ARthritis Disease Activity Score (PASDAS, is currently being developed.

  15. Understanding Oracle Clinical

    CERN Document Server

    Johnson, Joan

    2007-01-01

    This Short Cut is written to assist you, an Oracle Clinical Developer, with many of the tasks and decisions you may encounter on an occasional basis. These tasks involve study setup and maintenance, account maintenance, handling discrepancies, preparing data sets for analysis, batch-loading data, altering system-level settings and defining standard processes. A working knowledge of screen setup and procedure coding is assumed. Remote Data Capture (RDC), which moves data entry from the CRO or pharmaceutical company to the sites, is fast becoming the preferred way to gather and clean data for

  16. [Rickettsiosis: a clinical approach].

    Science.gov (United States)

    Boillat, N; Greub, G

    2007-05-16

    Rickettsiosis are zoonotic diseases transmitted to humans by arthropods. Prevalence of imported disease increases in parallel to the frequency of international travel. Clinical presentation is characterised by fever, headache and rash. Delay in the initiation of an antibiotic treatment efficient on Rickettsia spp. may have fatal impact on evolution. Serology is the more widely used diagnostic test. However, it only provides retrospective diagnosis. Polymerase chain reaction (PCR) and immunohistochemistry may provide early diagnosis. Doxycyclin is the first-line treatment and should be given empirically as soon as a rickettsial disease is suspected. PMID:17585624

  17. Clinical Doppler ultrasound

    International Nuclear Information System (INIS)

    The authors begin with the basics: how Doppler signals are formed, reflected, and refracted - and how those facts apply to clinical practice; anatomy (blood and blood flow), the Doppler equation (explained from a radiologic, rather than a mathematical, perspective); and approaches to Doppler signal production. The available methods of signal processing - including audio, multifilter analysis, zero-crossing detection, autocorrelation, and the Fast Fourier Transform, as well as more sophisticated techniques of duplex and color flow imaging - are covered with an eye to helping the ultrasonographer obtain the most reliable and artifact-free information from every Doppler reading

  18. Clinical review on RIT

    International Nuclear Information System (INIS)

    Full text of publication follows. Radioimmunotherapy (RIT) has been in use for more than 20 years and has progressed significantly with the discovery of new molecular targets, the development of new stable chelates, the humanization of monoclonal antibodies (MAbs), and the use of pre-targeting techniques. Today, 2 products targeting the CD20 antigen are approved in the treatment of B lymphoma: 131-tositumomab (Bexxar) and 90Y-ibritumomab tiuxetan (Zevalin). RIT can be applied in clinical practice for patients with relapsed or refractory follicular lymphoma (FL) or as consolidation after induction chemotherapy in front-line treatment in FL patients. Hematological toxicity is the major side effect of RIT and depends on bone marrow involvement and prior treatment. High-dose treatment, RIT as consolidation, RIT in first-line treatment, fractionated RIT and use of new humanized MAbs, in particular targeting CD22, showed promising results in B lymphoma. Targeting of antigens other than CD20 appears particularly interesting in the context of consolidation therapy after rituximab-based therapy. In other hemopathies, such as multiple myeloma (MM), RIT efficacy has been suggested in preclinical studies. Syndecan-1 is expressed in all MM and preclinical studies showed promising results using 213Bi-labeled anti-CD138. In solid tumors, more resistant to radiations and less accessible to large molecules such as MAbs, clinical efficacy remains limited. However, RIT used in minimal or small-size metastatic disease has shown promising clinical efficacy. Pre-targeting approaches have shown potential in increasing the therapeutic index of radiolabeled antibodies. Recently, a phase II clinical trial showed efficacy of anti-CEA pre targeted 131I-RIT in 42 progressive medullary thyroid carcinoma patients. Disease control according RECIST criteria (objective response + stabilization) was observed in 32 patients (76.2%), including one durable CR of at least 40 months and 31 durable

  19. HIV/AIDS Clinical Trials

    Science.gov (United States)

    ... Home Apps APIs Widgets Order Publications Skip Nav HIV/AIDS Clinical Trials Home > Clinical Trials Español small ... Renal (Kidney) Complications/Damage Skin Diseases FDA-Approved HIV Drugs Abacavir Atazanavir Atripla Cobicistat Combivir Complera Darunavir ...

  20. Rare Diseases Clinical Research Network

    Science.gov (United States)

    ... RDCRN? Aims of the Rare Diseases Clinical Research Network Contact Us RDCRN Members Login Accessibility Disclaimer The Rare Diseases Clinical Research Network is an initiative of the Office of Rare ...

  1. Clinical Issues-March 2016.

    Science.gov (United States)

    Burlingame, Byron L; Chambers, Kerrie

    2016-03-01

    Increasing ambient room temperature Key words: OR temperature, core temperature, unplanned hypothermia, ambient room temperature, thermoregulation. Clinical alarm management Key words: alarm fatigue, clinical alarms, alert alarms. PMID:26924373

  2. AIDS Clinical Trials Group Network

    Science.gov (United States)

    ... Center Statistical and Data Management Center Glossaries Sites Clinical Trials About the Trial Process Trials Open to Enrollment Recent Study Results Access to Published Data Clinical Trials Resources Committees Executive Scientific Resource Community General Information ...

  3. Clinical Investigator Inspector List (CLIIL)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Clinical Investigator Inspection List (CLIIL) contains names, addresses, and other pertinent information gathered from inspections of clinical investigators who...

  4. Evidence-based clinical practice

    DEFF Research Database (Denmark)

    Gluud, Christian

    2002-01-01

    Evidence-based medicine combines the patient's preferences with clinical experience and the best research evidence. Randomized clinical trials are considered the most valid research design for evaluating health-care interventions. However, empirical research shows that intervention effects may be...... evidence in clinical practice. By investments in education, applied research, and The Cochrane Collaboration, evidence-based medicine may form a stronger basis for clinical practice....

  5. Clinical Verification of Homeopathy

    Directory of Open Access Journals (Sweden)

    Michel Van Wassenhoven

    2011-07-01

    Full Text Available The world is changing! This is certainly true regarding the homeopathic practice and access to homeopathic medicine. Therefore our first priority at the ECH-LMHI [1] has been to produce a yearly report on the scientific framework of homeopathy. In the 2010 version a new chapter about epidemic diseases has been added including the Leptospirosis survey on the Cuban population. A second priority has been to review the definition of the homeopathic medicines respecting the new framework generated by the official registration procedure and the WHO report. We are working now on a documented (Materia Medica and provings list of homeopathic remedies to facilitate the registration of our remedies. The new challenges are: first of all more good research proposals and as such more funding (possible through ISCHI + Blackie Foundation as examples [2]; international acceptance of new guidelines for proving and clinical verification of homeopathic symptoms (Proposals are ready for discussion; total reconsideration of the homeopathic repertories including results of the clinical verification of the symptoms. The world is changing, we are part of the world and changes are needed also for homeopathy!

  6. Thiamin in Clinical Practice.

    Science.gov (United States)

    Frank, Laura L

    2015-07-01

    Thiamin is a water-soluble vitamin also known as vitamin B1. Its biologically active form, thiamin pyrophosphate (TPP), is a cofactor in macronutrient metabolism. In addition to its coenzyme roles, TPP plays a role in nerve structure and function as well as brain metabolism. Signs and symptoms of thiamin deficiency (TD) include lactic acidosis, peripheral neuropathy, ataxia, and ocular changes (eg, nystagmus). More advanced symptoms include confabulation and memory loss and/or psychosis, resulting in Wernicke's encephalopathy and/or Wernicke's Korsakoff syndrome, respectively. The nutrition support clinician should be aware of patients who may be at risk for TD. Risk factors include those patients with malnutrition due to 1 or more nutrition-related etiologies: decreased nutrient intake, increased nutrient losses, or impaired nutrient absorption. Clinical scenarios such as unexplained heart failure or lactic acidosis, renal failure with dialysis, alcoholism, starvation, hyperemesis gravidarum, or bariatric surgery may increase the risk for TD. Patients who are critically ill and require nutrition support may also be at risk for TD, especially those who are given intravenous dextrose void of thiamin repletion. Furthermore, understanding thiamin's role as a potential therapeutic agent for diabetes, some inborn errors of metabolism, and neurodegenerative diseases warrants further research. This tutorial describes the absorption, digestion, and metabolism of thiamin. Issues pertaining to thiamin in clinical practice will be described, and evidence-based practice suggestions for the prevention and treatment of TD will be discussed. PMID:25564426

  7. Marketing applications for dental clinic

    OpenAIRE

    Čevela, Josef

    2010-01-01

    The essay deals with the marketing strategy of the dental clinic, more specifically the dental clinic Sorriso DENTAL s.r.o. It also analyses and describes the marketing mix. Based on these things, it offers certain recommendations for the clinic and its marketing conception.

  8. CLINICAL, EPIDEMIOLOGICAL AND MYCOLOGICA

    Directory of Open Access Journals (Sweden)

    Ratheesh T

    2014-09-01

    Full Text Available BACKGROUND: Tinea versicolor is a chronic, mild, usually asymptomatic infection of the stratum corneum. The lesions are discrete or confluent and appear as discolored or hypo pigmented areas of the skin. The affected areas are located principally on the chest, abdomen, upper extremities and back. The etiologic agent is the lipophilic yeast Pityrosporum orbiculare, part of the normal flora of the human skin. This study is undertaken to know “clinical, patterns of the disease with respect to morphology and distribution, associated conditions and epidemiological factors like age, sex distribution and seasonal variation of the disease”. METHODS: Two hundred patients of tinea versicolor were selected. Patients belonging to the age group of above 10 years and below 60 years belonging to both sexes were selected and included in the study group after taking consent. A detailed history was taken with particular reference to onset, duration, symptoms and treatment taken and were recorded. Factors like – seasonal variation, family history and presence of any associated illnesses was also noted. A thorough clinical examination was done with reference to the location, the color, the extent of the lesions, the margins, the type of lesions and the details were recorded. Potassium hydroxide (KOH examination and Wood’s lamp examination were done in all the patients before therapy. RESULTS: Out of 200 patients, majority of them belong to 2nd and 3rd decade of life (72%. The Male: Female ratio was 1.5:1. There was a family history of 16%. The trunk was the most common site involved. Majority of the patients had exacerbation in summer. The most common associated dermatoses were acne vulgaris, immunosuppression and infections. INTERPRETATION AND CONCLUSION: Tinea versicolor is a disease of worldwide distribution, although it is significantly more common in humid and tropical climates. The true incidence cannot be estimated precisely because the disease is

  9. Clinical nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine appears to be increasingly expanding both in its scope and its direct practical clinical usefullness. In view of the manifold possibilities offered by nuclear medicine this review has intentionally been very rapid and, if one will pardon the pun, a scunning approach to nuclear medicine applications. Only selected highlights in the expanding field of nuclear medicine were discussed. In the past 25 years nuclear medicine has emerged as an integrated medical discipline. It now plays a major role in patient management and has significantly expanded the physicians' diagnostic tools. As illustrated here, radionuclide procedures are currently applied in almost every medical speciality. In any event, the tests that comprise nuclear medicine have succeeded because they are rapid, effective, safe and insexpensive, and can be performed without discomfort for the patient. (orig.)

  10. Clinical application of PET

    Energy Technology Data Exchange (ETDEWEB)

    Lomena, Francisco [Hospital Clinico Villarroel, Barcelona (Spain). Nuclear Medicine]. E-mail: flomena@clinic.ub.es; Soler, Marina [CETIR Grup Medic. Esplkugues de Llobregat, Barcelona (Spain). PET Unit

    2005-10-15

    Positron emission tomography (PET) is an imaging modality that gives information on tissue metabolism and functionalism, different from other imaging techniques like computed tomography (CT) and magnetic resonance imaging (MRI), which provide anatomical or structural information. PET has reached its development in biomedical research because of its capacity to use analogous compounds of many endogenous substance as tracers, and to measure, in vivo and in a non-invasive way, their consumption by the different organs and tissues of the mammalian body. Fluorodeoxyglucose-F 18 (FDG) PET has been proven to be a tracer adequate for clinical use in oncology and in many neurological diseases, with an excellent cost-efficiency ratio. The current PET-CT scanners can come to be the best tools for exploring patients who suffer from cancer.(author)

  11. Clinical pharmacokinetics of melatonin

    DEFF Research Database (Denmark)

    Harpsøe, Nathja Groth; Andersen, Lars Peter Holst; Gögenur, Ismail;

    2015-01-01

    PURPOSE: The aim of the review was to provide an overview of studies investigating the pharmacokinetics of exogenous melatonin in humans and if possible, to provide recommendations for clinical use. METHODS: The review was conducted in accordance to PRISMA guidelines. A systematic literature search...... was performed in PubMed and Embase databases. The pharmacokinetic variables included maximal plasma/serum concentration (Cmax), time to maximal plasma/serum concentration (Tmax), elimination half-life (T1/2), area-under-the-curve plasma/serum concentrations (AUC), clearance (Cl), volume of...... between 35 (0.005 mg, IV) and 1602 L (4 mg, oral). Bioavailability of oral melatonin ranged from 9 to 33%. Pharmacokinetics was affected by age, caffeine, smoking, oral contraceptives, feeding status, and fluvoxamine. Critically ill patients displayed accelerated absorption and compromised elimination...

  12. Clinical pharmacokinetics of anticonvulsants.

    Science.gov (United States)

    Hvidberg, E F; Dam, M

    1976-01-01

    Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies. The most important advantage is that the frequent interindividual variation in the plasma level/dose ratio for these drugs can be circumvented by plasma level monitoring. For several anticonvulsants the brain concentration is shown to parallel the plasma concentration. Phenytoin (diphenylhydantoin) is stil the most important anticonvulsant and the one for which kinetics have been thoroughly investigated in man. These investigations have revealed several reasons for the wellknown difficulties in using this drug clinically. The absorption rate and fraction are very much dependent on the pharmaceutical preparation, and changes of brand may alter the plasma level of phenytoin in spite of unaltered dose. The elimination capacity is saturable causing dose dependent kinetics, which again means disproportional changes in plasma level with changes in dose. Great individual variations exist in the rate of metabolism, and several pharmacokinetic drug interactions are known. As an optimum therapeutic plasma concentration range has been established monitoring plasma levels must be strongly advocated. Interpretation of plasma levels in uraemic patients must take into account decreased protein binding of the drug. Carbamazepine is probably as effective as phenytoin. The elimination is a first order process, but the rate of metabolism increases after a few weeks' treatment. An active metabolite (epoxide) may be the cause of some side-effects. Combined treatment with other anticonvulsant drugs decreases the half-life and more frequent dosing may be necessary. An optimum therapeutic concentration range has been suggested and plasma monitoring is advocated, along with that of the active metabolite, the epoxide. Phenobarbitone is still much used but its kinetics have been investigated to a lesser extent. The main problem is the variability in the rate of elimination. In children the half

  13. Gateways to clinical trials.

    Science.gov (United States)

    Tomillero, A; Moral, M A

    2008-10-01

    Gateways to clinical trials is a guide to the most recent trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity(R), the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: (+)-Dapoxetine hydrochloride, (S)-Tenatoprazole sodium salt monohydrate 19-28z, Acotiamide hydrochloride hydrate, ADV-TK, AE-37, Aflibercept, Albinterferon alfa-2b, Aliskiren fumarate, Asenapine maleate, Axitinib; Bavituximab, Becatecarin, beta-1,3/1,6-Glucan, Bevacizumab, Bremelanotide; Calcipotriol/betamethasone dipropionate, Casopitant mesylate, Catumaxomab, CDX-110, Cediranib, CMD-193, Cositecan; Darinaparsin, Denosumab, DP-b99, Duloxetine hydrochloride; E75, Ecogramostim, Elacytarabine, EMD-273063, EndoTAG-1, Enzastaurin hydrochloride, Eplerenone, Eribulin mesilate, Esomeprazole magnesium, Etravirine, Everolimus, Ezetimibe; Faropenem daloxate, Febuxostat, Fenretinide; Ghrelin (human); I-131 ch-TNT-1/B, I-131-3F8, Iclaprim, Iguratimod, Iloperidone, Imatinib mesylate, Inalimarev/Falimarev, Indacaterol, Ipilimumab, Iratumumab, Ispinesib mesylate, Ixabepilone; Lapatinib ditosylate, Laquinimod sodium, Larotaxel dehydrate, Linezolid, LOR-2040; Mapatumumab, MKC-1, Motesanib diphosphate, Mycophenolic acid sodium salt; NK-012; Olanzapine pamoate, Oncolytic HSV, Ortataxel; Paclitaxel nanoparticles, Paclitaxel poliglumex, Paliperidone palmitate, Panitumumab, Patupilone, PCV-9, Pegfilgrastim, Peginterferon alfa-2a, Peginterferon alfa-2b, Pertuzumab, Picoplatin, Pimavanserin tartrate, Pimecrolimus, Plerixafor hydrochloride, PM-02734, Poly I:CLC, PR1, Prasugrel, Pregabalin, Progesterone caproate, Prucalopride, Pumosetrag hydrochloride; RAV-12, RB-006, RB-007, Recombinant human erythropoietin alfa, Rimonabant, Romidepsin; SAR-109659, Satraplatin, Sodium butyrate; Tadalafil, Talampanel, Tanespimycin, Tarenflurbil, Tariquidar

  14. Calcitonin radioimmunoassay: clinical application

    International Nuclear Information System (INIS)

    A radioimmunoassay for human Calcitonin (hCT) was established: antisera were produced by immunizing goats with synthetic hCT; 7.5 μg hCT were labelled with 1 mCi 125J; hCT of different quantities in the range between 0.1 to 20 ng/ml served as standard. Separation of free from antibody bound tracer was done using the charcoal procedure. - This RIA-system was sensitive to determine 0.1 ng/ml; the normal range lying below 0.5 ng/ml. This assay was used to study the following clinical problems: 1) in 31 patients, with a thyroid tumor, diagnosis of calcitonin producing medullary thyroid carcinoma was proven. Serum calcitonin of these patients were lying between 1.7 and 120 ng/ml. Clinical signs of this disease are nonspecific, so CT determination is of importance for early diagnosis and control of therapy. In patients with a high tumor risk pentapastrin stimulation of the C-cells reveals calcitonin secretion above normal, if a medullary thyroid carcinoma is present. 2) two patients with pheochromocytoma showed elevated levels of CT before operation; after removal of the tumor serum CT was normalized. Extracts of the adreno-medullary tumor revealed immunoreactive CT corresponding to 4 and 1 ng/ml wet weight. - 3) CT is used for therapy of Paget's disease of the bone, so control of antibody development in the patients is necessary. In 25 patients with Paget's disease no antibody production against the injected hormone was evident. (orig.)

  15. Calcitonin radioimmunoassay. Clinical application

    International Nuclear Information System (INIS)

    A radioimmunoassay for human calcitonin (hCT) was established. Antisera were produced by immunizing goats with synthetic hCT; 7.5 μg of hCT was labelled with 1 mCi of 125I; hCT served as a standard in the range between 0.1 to 20 ng/ml. Separation of free from antibody-bound tracer was done with a charcoal procedure. The RIA system had a sensitivity of 0.1 ng/ml, the normal range lying below 0.5 ng/ml. The assay was used to study the following clinical problems: (1) In 35 patients with a thyroid tumour, diagnosis of calconin-producing medullary thyroid carcinoma was proven. Serum CT of these patients lay between 1.7 and 120 ng/ml. Clinical signs of this disease are non-specific, so CT determination is important for early diagnosis and control of therapy. In patients with a high tumour risk, pentagastrin stimulation of the C-cells reveals CT secretion above normal if a medullary thyroid carcinoma is present. (2) Two patients with pheochromocytoma showed elevated levels of hCT before operation; after removal of the tumour, the serum CT levels became normal. Extracts of the adrenomedullary tumour revealed immunoreactive CT corresponding to 1 and 4 ng/mg wet weight. (3) hCT is used in the therapy of Paget's disease of the bone, so it is necessary to check the production of antibodies in the patient. In 25 patients with Paget's disease no antibody production against the injected hormone was evident. (author)

  16. Emotional dysregulation in non-clinical and clinical subjects

    OpenAIRE

    Maffei, C; Fossati, A.; V. Ponissi; Bertoli, S; Strepparava, MG; Borroni, S.

    2012-01-01

    Emotional dysregulation is a complex pattern of reactivity to reality stimuli that now can be empirically studied. The dysregulation of emotion rating scale (DERS, Gratz and Roamer, 2004 ) seems tobea good instrument to evaluate the components and the phases of the process of emotional dysregulation. In this presentation, the data from Italian clinical and non-clinical population will be discussed. Clinical subjects will be: borderline personality disorder BPD obesity with binge eating obesit...

  17. How GPs implement clinical guidelines in everyday clinical practice

    DEFF Research Database (Denmark)

    Videbæk Le, Jette; Hansen, Helle P; Riisgaard, Helle;

    2015-01-01

    . OBJECTIVE: To investigate how GPs implement clinical guidelines in everyday clinical practice and how implementation approaches differ between practices. METHODS: Individual semi-structured open-ended interviews with seven GPs who were purposefully sampled with regard to gender, age and practice form....... Interviews were recorded, transcribed verbatim and then analysed using systematic text condensation. RESULTS: Analysis of the interviews revealed three different approaches to the implementation of guidelines in clinical practice. In some practices the GPs prioritized time and resources on collective......'s decision on whether and how to manage implementation. CONCLUSION: Approaches to implementation of clinical guidelines vary substantially between practices. Supporting activities should take this into account....

  18. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... Systematic Evidence Reviews & Clinical Practice Guidelines Resources Continuing Education Researchers Funding Training & Career Development Division of Intramural Research Research Resources Research Meeting ...

  19. Gateways to clinical trials.

    Science.gov (United States)

    Bayés, M; Rabasseda, X; Prous, J R

    2005-06-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: Abiraterone acetate, acyline, adalimumab, adenosine triphosphate, AEE-788, AIDSVAX gp120 B/B, AK-602, alefacept, alemtuzumab, alendronic acid sodium salt, alicaforsen sodium, alprazolam, amdoxovir, AMG-162, aminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, aminophylline hydrate, anakinra, anecortave acetate, anti-CTLA-4 MAb, APC-8015, aripiprazole, aspirin, atazanavir sulfate, atomoxetine hydrochloride, atorvastatin calcium, atrasentan, AVE-5883, AZD-2171; Betamethasone dipropionate, bevacizumab, bimatoprost, biphasic human insulin (prb), bortezomib, BR-A-657, BRL-55730, budesonide, busulfan; Calcipotriol, calcipotriol/betamethasone dipropionate, calcium folinate, capecitabine, capravirine, carmustine, caspofungin acetate, cefdinir, certolizumab pegol, CG-53135, chlorambucil, ciclesonide, ciclosporin, cisplatin, clofarabine, clopidogrel hydrogensulfate, clozapine, co-trimoxazole, CP-122721, creatine, CY-2301, cyclophosphamide, cypher, cytarabine, cytolin; D0401, darbepoetin alfa, darifenacin hydrobromide, DASB, desipramine hydrochloride, desloratadine, desvenlafaxine succinate, dexamethasone, didanosine, diquafosol tetrasodium, docetaxel, doxorubicin hydrochloride, drotrecogin alfa (activated), duloxetine hydrochloride, dutasteride; Ecallantide, efalizumab, efavirenz, eletriptan, emtricitabine, enfuvirtide, enoxaparin sodium, estramustine phosphate sodium, etanercept, ethinylestradiol, etonogestrel, etonogestrel/ethinylestradiol, etoposide, exenatide; Famciclovir, fampridine, febuxostat, filgrastim, fludarabine phosphate, fluocinolone acetonide, fluorouracil, fluticasone propionate

  20. Clinical Predictors of Psychopathology

    Directory of Open Access Journals (Sweden)

    Jorge Caraveo Anduaga

    2010-04-01

    Full Text Available Psychiatric disorders affect up to one third of patients with non-psychiatric diseases.1-5 Nevertheless, despite the high prevalence of psychopathology in general medical patients, only between 30-50% of all cases are detected.2,6-8 Some have suggested that the difficulty in the detection and diagnosis of mental disorders among patients who seek medical attention for other reasons, lies in the lack of screening questions that might alert the physician to the possibility of a psychiatric co-morbidity.9 Such questions would identify medical patients at high risk of psychiatric problems. Previous work on clinical predictors of psychopathology have identified the following: specific physical symptoms10-11; patient report of severity of illness11; recent stress12,13; low self-perception of health status13; and age less than 50.14 Two specific studies on the detection of psychopathology in the general medical population are worth highlighting. The first, by Jackson and his research team13 updating a 2001 study evaluating a prediction model with four parameters (recent stress, severity of physical symptoms, five or more specific symptoms, self-assessment of physical condition. They found that those patients who report recent stress, have five or more physical symptoms or a low self-perception of their health state are at a higher risk of having a psychiatric disorder. The second study, by Lowe et al. published in 2003,9 examines a series of factors that could serve as indicators of psychopathology in ambulatory medical (i.e. non-psychiatric patients. After evaluating several different models they found that the combination of four of factors (taken as a group had a high sensitivity (86%, specificity (100%, positive predictive value (100%, and negative predictive value (91%. This suggests that a physician could use the combination of these four indicators to evaluate for the presence of co morbid mental disorders. These factors are: self

  1. Demystifying the reflective clinical journal

    International Nuclear Information System (INIS)

    Student learning on clinical placement is a complex issue and cannot be defined solely by just doing things. Reflection during clinical practice is essential if the student is going to learn from the experience. Therefore it is important for educators to include as part of clinical education programs learning strategies that encourage reflection. The reflective clinical journal is an educational tool that is employed by the School of Medical Radiation Sciences at the University of Sydney to encourage reflection of undergraduate radiation therapy students whilst on clinical placement. This discussion paper explores the key concepts of reflection and the reflective clinical journal. Due to the paucity of information about this issue in radiation therapy the literature reviewed is from across all areas of the health sciences

  2. Demystifying the reflective clinical journal

    Energy Technology Data Exchange (ETDEWEB)

    Milinkovic, Danielle [School of Medical Radiation Sciences, Faculty of Health Sciences, University of Sydney, PO Box 170, Lidcombe NSW 1825 (Australia)]. E-mail: d.milinkovic@fhs.usyd.edu.au; Field, Nikki [School of Medical Radiation Sciences, Faculty of Health Sciences, University of Sydney, PO Box 170, Lidcombe NSW 1825 (Australia)

    2005-08-01

    Student learning on clinical placement is a complex issue and cannot be defined solely by just doing things. Reflection during clinical practice is essential if the student is going to learn from the experience. Therefore it is important for educators to include as part of clinical education programs learning strategies that encourage reflection. The reflective clinical journal is an educational tool that is employed by the School of Medical Radiation Sciences at the University of Sydney to encourage reflection of undergraduate radiation therapy students whilst on clinical placement. This discussion paper explores the key concepts of reflection and the reflective clinical journal. Due to the paucity of information about this issue in radiation therapy the literature reviewed is from across all areas of the health sciences.

  3. Clinical parotid carcinoma analysis

    International Nuclear Information System (INIS)

    We clinically analyzed 48 consecutive retrospective cases of parotid carcinoma initially treated between 1988 and 2007. Subjects were 30 males and 18 females ranging from 5 to 85 years old (average: 57.9 years). Of the 12 histological types seen, the most common was mucoepidermoid carcinoma, seen in 12 subjects (25.0%). We studied their survival based on 5 potential prognostic factors-stage, T stage, neck metastasis, facial nerve palsy, and malignancy grade-together with features of mortality and recurrence. Overall 5-year disease-specific survival was 71.2% and 10-year survival 54.9%. Survival rates were significantly lower in stage IV and high-grade malignancy groups than in stage I-III and low-grade malignancy groups. T stage, neck metastasis, and facial nerve palsy tended to compromise survival. Recurrence developed in 2 subjects, in whom significant recurrence risk factors were stage III-IV (particularly, stage IV), T3-4, and high-grade malignancy. Of 18 deaths, causes were distant failure in 11 and local failure in 5. None died of nodal failure. Analysis of these prognostic factors is important in selecting appropriate surgery and in determining indications for postoperative radiotherapy and chemotherapy, leading to better treatment outcome in those with parotid carcinoma. (author)

  4. Overview of Clinical Cytogenetics.

    Science.gov (United States)

    Gonzales, Patrick R; Carroll, Andrew J; Korf, Bruce R

    2016-01-01

    Chromosome analysis is one of the first approaches to genetic testing and remains a key component of genetic analysis of constitutional and somatic genetic disorders. Numerical or unbalanced structural chromosome abnormalities usually lead to multiple congenital anomalies. Sometimes these are compatible with live birth, usually resulting in severe cognitive and physical handicaps; other times they result in miscarriage or stillbirth. Chromosome rearrangements also occur as somatic changes in malignancies. Identification of constitutional chromosomal anomalies (anomalies present in most or all cells of the body and/or the germline) can provide important information for genetic counseling. In this unit, we introduce chromosomal microarray analysis (CMA), which is a relatively recent addition to cytogenetic technologies, and has become the recommended first-tier testing method for patients with developmental delay, intellectual disability, autism, and/or multiple congenital anomalies. We also discuss non-invasive prenatal testing/screening (NIPTS), which uses circulating cell-free fetal DNA (cfDNA) from maternal plasma to rapidly screen for autosomal and sex-chromosome aneuploidies. Cytogenetic analysis of tumors is helpful in diagnosis and in monitoring the effects of treatment. The protocols in this chapter cover the clinical study of chromosomes in nonmalignant tissues. © 2016 by John Wiley & Sons, Inc. PMID:27037488

  5. Virtual colonoscopy: clinical application

    International Nuclear Information System (INIS)

    Virtual colonoscopy (VC), also known as computed tomography Colonography (CTC), is a non-invasive test for the examination of the colon based on volumetric, thin-collimation CT acquisition of a cleansed and air-distended colon. The technique is easy, less labour-intensive than barium enema and conventional colonoscopy, and is inherently safer. Several studies demonstrate the ability of VC in the detection of colonic neoplastic lesions, not only large carcinomas, but also polyps. Currently, the most widely accepted clinical indication is incomplete or unsuccessful colonoscopy, which may be the result of redundant colon, patient intolerance to the procedure, spasm not resolving even with the use of spasmolytics, obstructing colo-rectal cancer. VC is also used to detect cancer in frail and immobile patients to avoid sedation during colonoscopy or the turning required during barium enema. The use of VC in patients under surveillance following colo-rectal cancer surgery is under investigation. Further studies are necessary in order to assess the cost-effectiveness of this approach. For colo-rectal cancer screening, a practical approach is to consider VC as a currently credible alternative screening method and as a reasonable alternative to the other colo-rectal cancer screening tests when a patient is unable or unwilling to undergo conventional colonoscopy. (orig.)

  6. The Dynamo Clinical Trial

    Science.gov (United States)

    Ayres, Thomas R.

    2016-04-01

    The Dynamo Clinical Trial evaluates long-term stellar magnetic health through periodic X-ray examinations (by the Chandra Observatory). So far, there are only three subjects enrolled in the DTC: Alpha Centauri A (a solar-like G dwarf), Alpha Cen B (an early K dwarf, more active than the Sun), and Alpha Canis Majoris A (Procyon, a mid-F subgiant similar in activity to the Sun). Of these, Procyon is a new candidate, so it is too early to judge how it will fare. Of the other two, Alpha Cen B has responded well, with a steady magnetic heartbeat of about 8 years duration. The sickest of the bunch, Alpha Cen A, was in magnetic cardiac arrest during 2005-2010, but has begun responding to treatment in recent years, and seems to be successfully cycling again, perhaps achieving a new peak of magnetic health in the 2016 time frame. If this is the case, it has been 20 years since A's last healthful peak, significantly longer than the middle-aged Sun's 11-year magnetic heartbeat, but perhaps in line with Alpha Cen A's more senescent state (in terms of "relative evolutionary age," apparently an important driver of activity). (By the way, don't miss the exciting movie of the Alpha Cen stars' 20-year X-ray dance.)

  7. Clinical definition of sarcopenia.

    Science.gov (United States)

    Santilli, Valter; Bernetti, Andrea; Mangone, Massimiliano; Paoloni, Marco

    2014-09-01

    Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Although it is primarily a disease of the elderly, its development may be associated with conditions that are not exclusively seen in older persons. Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength and it is strictly correlated with physical disability, poor quality of life and death. Risk factors for sarcopenia include age, gender and level of physical activity. In conditions such as malignancy, rheumatoid arthritis and aging, lean body mass is lost while fat mass may be preserved or even increased. The loss in muscle mass may be associated with increased body fat so that despite normal weight there is marked weakness, this is a condition called sarcopenic obesity. There is an important correlation between inactivity and losses of muscle mass and strength, this suggests that physical activity should be a protective factor for the prevention but also the management of sarcopenia. Furthermore one of the first step to be taken for a person with sarcopenia or clinical frailty is to ensure that the sarcopenic patient is receiving correct and sufficient nutrition. Sarcopenia has a greater effect on survival. It should be important to prevent or postpone as much as possible the onset of this condition, to enhance survival and to reduce the demand for long-term care. Interventions for sarcopenia need to be developed with most attention on exercise and nutritional interventions. PMID:25568649

  8. The clinical encounter revisited.

    Science.gov (United States)

    Schattner, Ami

    2014-04-01

    The patient-physician encounter is the pivotal starting point of any healthcare delivery, but it is subject to multiple process breakdowns and prevalent suboptimal performance. An overview of the techniques and components of a successful encounter valid for every setting and readily applicable is presented, stressing 7 rules: (1) ensuring optimal environment, tools, and teamwork; (2) viewing each encounter not only as a cognitive/biomedical challenge, but also as a personal one, and a learning opportunity; (3) adopting an attitude of curiosity, concentration, compassion, and commitment, and maintaining a systematic, orderly approach; (4) "simple is beautiful"-making the most of the basic clinical data and their many unique advantages; (5) minding "the silent dimension"-being attentive to the patient's identity and emotions; (6) following the "Holy Trinity" of gathering all information, consulting databases/colleagues, and tailoring gained knowledge to the individual patient; and (7) using the encounter as a "window of opportunity" to further the patient's health-not just the major problem, by addressing screening and prevention; promoting health literacy and shared decision-making; and establishing proper follow-up. Barriers to implementation identified can be overcome by continuous educational interventions. A high-quality encounter sets a virtuous cycle of patient-provider interaction and results in increasing satisfaction, adherence, and improved health outcomes. PMID:24333201

  9. Pediatric DXA: clinical applications

    Energy Technology Data Exchange (ETDEWEB)

    Binkovitz, Larry A. [Columbus Children' s Hospital, Department of Radiology, Columbus, OH (United States); Sparke, Paul [Capital University, Department of Chemistry, Columbus, OH (United States); Henwood, Maria J. [Columbus Children' s Hospital, Department of Endocrinology, Columbus, OH (United States)

    2007-07-15

    Normal bone mineral accrual requires adequate dietary intake of calcium, vitamin D and other nutrients; hepatic and renal activation of vitamin D; normal hormone levels (thyroid, parathyroid, reproductive and growth hormones); and neuromuscular functioning with sufficient stress upon the skeleton to induce bone deposition. The presence of genetic or acquired diseases and the therapies that are used to treat them can also impact bone health. Since the introduction of clinical DXA in pediatrics in the early 1990s, there has been considerable investigation into the causes of low bone mineral density (BMD) in children. Pediatricians have also become aware of the role adequate bone mass accrual in childhood has in preventing osteoporotic fractures in late adulthood. Additionally, the availability of medications to improve BMD has increased with the development of bisphosphonates. These factors have led to the increased utilization of DXA in pediatrics. This review summarizes much of the previous research regarding BMD in children and is meant to assist radiologists and clinicians with DXA utilization and interpretation. (orig.)

  10. Clinical applications of radioimmunolocalisation

    International Nuclear Information System (INIS)

    Localization of tumours by external scintigraphy after intravenous administration of radiolabeled antibody directed against a tumour-associated antigen [radioimmunolocalisation (RIL)] might be expected to solve many of the problems of conventional tumour imaging. Although no truly specific tumour antigen is known, there are many tumour-associated antigens which are present in much higher concentrations in certain tumours than in tissues which are normal or affected by other diseases. This feature has the potential to endow RIL with a degree of specificity not exhibited by imaging methods such as computerised tomography (CT), ultrasound (US) or nuclear magnetic resonance (NMR) which reflect the physical characteristics of tissues. The clinical application of new imaging methods depends partly on their comparative performance in terms of sensitivity and specificity and also on ways in which the unique features of each can be exploited to optimize the management of individual patients. There are significant deficiencies with all the existing imaging methods; this chapter discusses the extent to which RIL may fill some of the gaps. Particular attention will be paid to situations where the result has consequences for patient management. Much of the work cited was carried out in experimental systems and on more than 300 patients at Charing Cross Hospital between 1979 and 1984

  11. Clinical studies in spinal surgery

    OpenAIRE

    Hanson, Beate; Kopjar, Branko

    2005-01-01

    There is a growing interest in applying evidence-based approaches also in orthopedic surgery. Despite many challenges to the validity of clinical trials in orthopedic surgery, it is possible to conduct well-designed trials in this field and to produce clinically important findings and reasonably valid conclusions about effectiveness, prognosis and diagnosis in orthopedic surgery. We describe the main principles for conducting clinical trials in this field as well as some of the most common er...

  12. Photodynamic therapy in clinical practice

    OpenAIRE

    E. V. Filonenko; L. G. Serova

    2016-01-01

    The review is on opportunities and possibilities of application of photodynamic therapy in clinical practice. The advantages of this method are the targeting of effect on tumor foci and high efficiency along with low systemic toxicity. The results of the set of recent Russian and foreign clinical trials are represented in the review. The method is successfully used in clinical practice with both radical (for early vulvar, cervical cancer and pre-cancer, central early lung cancer, esophageal a...

  13. Clinical hypertension: a new era

    OpenAIRE

    Ha, Jong-Won

    2014-01-01

    We are delighted to announce the launch of the new journal Clinical Hypertension. Clinical Hypertension is an open-access, peer-reviewed, online journal, which will publish scientific investigation of the highest quality in the field of blood pressure regulation and pathophysiology, treatment, and prevention of hypertension. The editors encourage the submission of original articles that deal with basic, clinical, and population studies of hypertension and related fields, such as cardiology, n...

  14. Crisis of the clinical method

    OpenAIRE

    Miguel Moreno Rodríguez

    2010-01-01

    This is an opinion paper. The author identifies an universal crisis of the clinical method, with dangerous consequences in the practice of medicine. Among its main causes, there are discussed: a deterioration in the doctor-patient relationship, the undervaluation of clinics, the overvaluation of technology, and the indifference for general medicine. A call for attention is made for the restoration of clinical method values and to permanent seed its principles in all medical students and young...

  15. Clinical psychology and child protection

    OpenAIRE

    O'Brien, Elaine; Carey, Sean; Carr, Alan.

    2000-01-01

    In this 1998 postal survey of 140 clinical psychologists working in eight Health Boards and Voluntary agencies in the Republic of Ireland, it was found that clinical psychologists from child mental health, adult mental health and services for people with physical and intellectual disabilities were involved in child abuse and protection work. Clinical psychologists' child protection work spanned a number of domains including validation, general assessment, risk assessment, treatment of victims...

  16. Turnaround for the Denver Clinic.

    Science.gov (United States)

    Norris, M J

    1981-01-01

    By renovating its facility, the Denver Clinic was able to meet the needs of its present patient population and attract new patients. Marketing techniques were employed to redesign the facility and to capitalize on the clinic's competitive edge in the Denver market. Useful information is offered to other clinics who are considering facility renovation and on the advantages group practices have in the medical market plan. PMID:10252836

  17. Unusual clinical manifestations of leptospirosis

    OpenAIRE

    Bal A

    2005-01-01

    Leptospirosis has protean clinical manifestations. The classical presentation of the disease is an acute biphasic febrile illness with or without jaundice. Unusual clinical manifestations may result from involvement of pulmonary, cardiovascular, neural, gastrointestinal, ocular and other systems. Immunological phenomena secondary to antigenic mimicry may also be an important component of many clinical features and may be responsible for reactive arthritis. Leptospirosis in early pregnancy may...

  18. Is a clinical sociolinguistics possible?

    Science.gov (United States)

    Ball, M J

    1992-01-01

    This paper considers the idea of developing a clinical sociolinguistics. Various areas of the field are examined, and the importance of the 'core' area of the correlation of non-linguistic variables with linguistic variables stressed. Issues concerning language and class, region, sex, age and context of utterance are investigated, together with the implications for clinical linguistics. Finally, the difficulty of integrating such issues into clinical assessment is explored, and a tentative step forward suggested along the lines of a 'clinical sociolinguistic checklist'. PMID:20672890

  19. Clinical governance and external audit.

    Science.gov (United States)

    Glazebrook, S G; Buchanan, J G

    2001-01-01

    This paper describes a model of clinical governance that was developed at South Auckland Health during the period 1995 to 2000. Clinical quality and safety are core objectives. A multidisciplinary Clinical Board is responsible for the development and publicising of sound clinical policies together with monitoring the effects of their implementation on quality and safety. The Clinical Board has several committees, including an organization-wide Continuous Quality Improvement Committee to enhance the explicit nature of the quality system in terms of structure, staff awareness and involvement, and to develop the internal audit system. The second stream stems from the Chief Medical Officer and clinical directors in a clinical management sense. The Audit Committee of the Board of Directors covers both clinical and financial audit. The reporting lines back to that committee are described and the role of the external auditor of clinical standards is explained. The aim has been to create a supportive culture where quality initiatives and innovation can flourish, and where the emphasis is not on censure but improvement. PMID:11422717

  20. Clinical research in allied health.

    Science.gov (United States)

    Selker, L G

    1994-01-01

    Allied health professionals in nutrition and medical dietetics, occupational therapy, physical therapy, and speech-language pathology and audiology play both unique and key cross-cutting roles in the furtherance of clinical research. Clinical research in nutrition and medical dietetics uniquely focuses on food nutrient intake and the metabolic utilization of nutrients. Clinical research in occupational therapy has a special focus on the relationship of impairment to disability, the adaptation to disability and the maximization of function. Physical therapy clinical research uniquely targets movement dysfunction and its evaluation and treatment within the context of quality and effective care. Clinical research in speech-language pathology and audiology is singular in its focus on deafness and hearing disorders, voice, speech, language and related disorders, and intersections among these and other neurological and physical conditions. Thus, all of these disciplines are making unique contributions to clinical research. Clinical research in these allied health professions is much more than the above specific foci. Inasmuch as these disciplines are rooted in practice, their contributions to research are inherently clinical. Many, if not most, of these contributions represent further validations of clinical practice or its underlying knowledge base. This means that, at a macro level, clinical research in allied health is very much "applied" research. Within allied health clinical research, this emphasis is redoubled at the "person," or individual level, where considerable attention is given to concepts of function and effectiveness. Clinical research in allied health has played a key cross-cutting role through its emphasis on collaboration. Possibly due to their professional maturation within multidisciplinary academic units, allied health professionals have demonstrated a level of comfort with multidisciplinary and interdisciplinary collaborations unique within many

  1. Clinic Health Awareness Program Subsystem

    Data.gov (United States)

    Department of Transportation — Clinic Health Awareness Program Subystem (CHAPS) is a comprehensive system for recording, reporting, and analyzing a patient’s medical information and managing an...

  2. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available U.S. Department of Health & Human Services National Institutes of Health Contact Us Get Email Alerts Font Size Accessible Search ... Health Topics Education & Awareness Resources Contact The Health Information Center ... Transfer Clinical Trials What Are Clinical Trials? Children & ...

  3. Integrating Academic and Clinical Learning Using a Clinical Swallowing Assessment

    Science.gov (United States)

    Phillips, Daniel E.

    2013-01-01

    This article describes an experiential learning activity designed to integrate classroom knowledge and a clinical swallowing assessment. Twenty master's-level graduate students in a dysphagia course conducted a clinical swallowing assessment with a resident of an independent retirement community. The exercise was designed to allow students an…

  4. Clinical outcomes in clinical trials of anti-HIV treatment

    DEFF Research Database (Denmark)

    Reekie, J; Mocroft, A; J, Neaton;

    2007-01-01

    Since the introduction of combination antiretroviral therapy, there has been a decrease in both AIDS-defining illnesses and deaths. This decrease meant that performing clinical trials with clinical outcomes in HIV infection became more time consuming and hence costly. Improved understanding and k...

  5. Designing for Anxiety Therapy, Bridging Clinical and Non-Clinical

    DEFF Research Database (Denmark)

    Bertelsen, Olav Wedege; Kramp, Gunnar

    2012-01-01

    In this position paper we discuss, in terms of the concept of boundary objects, how a mobile application, the MIKAT.app, bridge between clinical intervention in anxiety therapy, and life and coping strategies outside the clinic and across phases of being a person suffering from, or having suffered...... from anxiety. Thereby, we hope to provide a counterpoint in the discussion on illness trajectories....

  6. Complementary and Alternative Medicine Cancer Clinical Trials

    Science.gov (United States)

    ... Introduction Cancer CAM Clinical Trials Introduction What are clinical trials? A clinical trial is one of the final ... and effective. What are the different types of clinical trials? Treatment trials test new treatments (like a new ...

  7. Análisis del ajuste marginal y el ajuste interno en sistemas CAD-CAM de óxido de circonio

    OpenAIRE

    Ortega Sánchez, Rocío

    2012-01-01

    El interés por la estética dental ha estado íntimamente ligado a la historia y evolución de la Prótesis Dental, pero es a finales del siglo XIX cuando se desarrollan como materiales restauradores las cerámicas, y a comienzos del siglo XX cuando se confecciona la primera corona de recubrimiento total cerámica. Las cerámicas convencionales tenían su indicación limitada a restauraciones unitarias en los sectores anteriores debido fundamentalmente a su limitada resistencia a la fractura,...

  8. Movement: A Clinical Investigation

    Directory of Open Access Journals (Sweden)

    Kazem Dalaie

    2015-10-01

    Full Text Available Objectives: One major drawback of orthodontic treatment is its long duration due to slow tooth movement and the pain at the onset of treatment following application of forces. There is controversy regarding the efficacy of laser for decreasing the treatment time and pain of orthodontic treatment. The purpose of this study was to investigate the effect of low level diode laser on the rate of orthodontic tooth movement and the associated pain.Materials and Methods: In this double blind randomized controlled clinical trial, 12 or- thodontic patients referring to Shahid Beheshti School of Dentistry for first premolar ex- traction were randomly selected and allocated to gallium aluminum-arsenide laser (Ga,Al,As diode laser, 880 nm, 100 mW, 5 j/cm2, 8 points, 80 seconds, continuous mode or control group. The patients initially underwent leveling and alignment using the sectional system. Force (150 gr was applied to each canine tooth via sectional closing loops. The loops were activated every month. The rate of tooth movement and pain were monitored over the treatment period and recorded on days 1, 3, 7, 30, 33, 37, 60, 63 and 67. Two-way ANOVA was used for comparison of groups.Results: There was no significant difference in terms of tooth movement and pain scores between the irradiated and non-irradiated sides at any time point (P>0.05.Conclusion: Although laser enhanced orthodontic tooth movement in the upper jaw, we failed to provide solid evidence to support the efficacy of laser for expediting tooth move- ment or reducing the associated pain.

  9. Liver angioscintigraphy: clinical applications.

    Science.gov (United States)

    Dragoteanu, Mircea; Cotul, Sabin O; Pîgleşan, Cecilia; Tamaş, Stefan

    2004-03-01

    Liver angioscintigraphy (LAS) is a radio-isotope method for the investigation of liver perfusion and its alteration in various hepatic diseases. It measures the arterial and portal venous fractions of total liver blood flow. The percentage of liver blood flow supplied by hepatic artery is estimated mathematically by the hepatic perfusion index (HPI), normally between 25 % and 40 %. The decrease of portal blood flow in liver cirrhosis is compensated ("buffer" mechanisms) by increased arterial supply, with higher HPI value. For a patient with chronic liver disease, HPI over 50% suggests arterialization of hepatic perfusion, guiding the diagnose to liver cirrhosis. Splenic curve is completing the diagnostic information of the hepatic curve. Corroborated with per rectal scintigraphy and liver SPECT, LAS offers a good hemodynamic staging of chronic inflammatory liver diseases. Malignant tumors (primitive or metastases) increase the arterial supply of the liver and decrease the portal flow, HPI being over 50% (currently 65 % - 90 %). Benign tumors do not change portal/arterial liver blood flow ratio. SPECT or non-scintigraphic morphological investigations increase the diagnostic value of LAS for primitive liver tumors. Liver cancer occurring on cirrhosis is a limitative factor for LAS. Hepatic metastases increase the arterial perfusion (and HPI value) very quickly, before their size allows morphologic imaging diagnosis. LAS is therefore an early method to diagnose liver metastases being especially used in colorectal cancer. Other clinical applications of LAS are: follow up of liver toxicity of drugs, evaluation of portal vein permeability, post surgery follow up of the liver tumor patients. PMID:15054528

  10. Prospects in clinical hyperthermia

    International Nuclear Information System (INIS)

    A large number of patients have now been entered into a phase I/II protocol to examine the effects of fractionated hyperthermia and radiation on tumor response. Included in the study were 11 different histologies with anatomical locations varying between peripheral and superficial metastases to deep seated, solid tumors. Patients were treated with four fractions of microwave induced hyperthermia (45.0 +- 0.5 deg. C), each separated by intervals of 72 hours. Treatments were 1-1/2 hours in duration to a volume encompassing the tumor. Microwaves at frequencies of 915 MHz or 300 MHz were employed. Patients were given a one-week rest following the first 4 treatments, following which a second series of 4 fractions were administered again at 72-hour intervals. Each of these fractions consisted of a 400 rad dose of radiation followed within 20 minutes by hyperthermia (42.5 +- 0.5 deg. C) for 1-1/2 hours. To date 121 fields have been treated in 82 patients. New technology allows for the treatment of deep seated tumors in the neck, chest and pelvis. Follow-up times range from 2 to 19 months. Total regression is seen in 65% of all cases, partial regression in 35% and no response is seen in only 5% of treatments. Six local and four marginal recurrences have been observed. Adverse effects were rare. Based upon our results (above) and those of other investigators, several modifications have been made in the above protocol. Site specific trials are currently in progress to study both the feasibility of deep seated heating with intracavitary antennas as well as to assess tumor response. In addition, a randomized trial to examine the clinical relevance of thermotolerance has been started. (author)

  11. Clinical management of constipation.

    Science.gov (United States)

    Lennard-Jones, J E

    1993-10-01

    First, it is important to find out whether the patient is complaining of infrequent defaecation, excessive straining at defaecation, abdominal pain or bloating, a general sense of malaise attributed to constipation, soiling, or a combination of more than one symptom. Second, one must decide if there is a definable abnormality as a cause of the symptom(s). Is the colon apparently normal or is its lumen widened (megacolon)? Is the upper gut normal or is there evidence of neuropathy or myopathy? Is the ano-rectum normal or is there evidence of a weak pelvic floor, mucosal prolapse, major rectocele, an internal intussusception or solitary rectal ulcer? Is there any systemic component such as hypothyroidism, hypercalcaemia, neurological or psychiatric disorder or relevant drug therapy? Choice of treatment will depend on this clinical evaluation. The range of treatments available is: Reassurance and stop current treatment: Patients with a bowel obsession may take laxatives or rectal preparations regularly without need. Increase dietary fibre: Most cases of 'simple' constipation respond to increased dietary fibre, possibly with an added supplement of natural bran. Toilet training and altered routine of life: Young people particularly may need to recognise the call to stool and alter their daily routine to permit and encourage regular defaecation. Medicinal bulking agent: Ispaghula, methyl cellulose, concentrated wheat germ or bran, and similar preparations are useful when patients with a normal colon find it difficult to take adequate dietary fibre. These preparations increase the bulk of stool and soften its consistency. They may be useful for those patients with the constipated form of irritable bowel syndrome.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:8234432

  12. Lasers in clinical ophthalmology

    Science.gov (United States)

    Ribeiro, Paulo A.

    1992-03-01

    The clinical application of lasers in ophthalmology is schematized, showing for each anatomic eye structure, pathologies that may be treated through this procedure. In the cornea, the unusual laser practice for suture removals and the promising possibility of the excimer laser in refractive surgery are discussed. In the iris, the camerular angle, and the ciliary body, the laser application is essentially used to treat the glaucoma and other situations that are not so frequent. The capsulotomy with YAG LASER is used in the treatment of structures related with crystalline and, at least, the treatment of the retina and choroid pathology is expanded. A. A. explained the primordial interest and important of laser in the diabetic retinopathy treatment and some results in patients with more than 5 years of evolution are: 55 of the patients with proliferative diabetic retinopathy (RDP) treated for more than 5 years noticed their vision improved or stabilized; 5 years after treating patients with PDR, 49.3 had their vision stabilized or even improved, provided the diabetics had declared itself more than 20 years ago, versus 61.7 provided the diabetics had declared itself less than 20 years before; finally, 53.8 of the patients under 40-years-old when the diabetics was diagnosed, had their vision improved or at least stabilized 5 years after the beginning of the treatment. On the other side, when patients were over 40 years old when the diabetics was diagnosed percentage increased to 55.9. This study was established in the follow-up of 149 cases over 10 years.

  13. Providing semantic interoperability between clinical care and clinical research domains.

    Science.gov (United States)

    Laleci, Gokce Banu; Yuksel, Mustafa; Dogac, Asuman

    2013-03-01

    Improving the efficiency with which clinical research studies are conducted can lead to faster medication innovation and decreased time to market for new drugs. To increase this efficiency, the parties involved in a regulated clinical research study, namely, the sponsor, the clinical investigator and the regulatory body, each with their own software applications, need to exchange data seamlessly. However, currently, the clinical research and the clinical care domains are quite disconnected because each use different standards and terminology systems. In this article, we describe an initial implementation of the Semantic Framework developed within the scope of SALUS project to achieve interoperability between the clinical research and the clinical care domains. In our Semantic Framework, the core ontology developed for semantic mediation is based on the shared conceptual model of both of these domains provided by the BRIDG initiative. The core ontology is then aligned with the extracted semantic models of the existing clinical care and research standards as well as with the ontological representations of the terminology systems to create a model of meaning for enabling semantic mediation. Although SALUS is a research and development effort rather than a product, the current SALUS knowledge base contains around 4.7 million triples representing BRIDG DAM, HL7 CDA model, CDISC standards and several terminology ontologies. In order to keep the reasoning process within acceptable limits without sacrificing the quality of mediation, we took an engineering approach by developing a number of heuristic mechanisms. The results indicate that it is possible to build a robust and scalable semantic framework with a solid theoretical foundation for achieving interoperability between the clinical research and clinical care domains. PMID:23008263

  14. Clinical mastitis in ewes; bacteriology, epidemiology and clinical features

    Directory of Open Access Journals (Sweden)

    Kvitle Bjørg

    2007-09-01

    Full Text Available Abstract Background Clinical mastitis is an important disease in sheep. The objective of this work was to identify causal bacteria and study certain epidemiological and clinical features of clinical mastitis in ewes kept for meat and wool production. Methods The study included 509 ewes with clinical mastitis from 353 flocks located in 14 of the 19 counties in Norway. Clinical examination and collection of udder secretions were carried out by veterinarians. Pulsed-field gel electrophoresis (PFGE was performed on 92 Staphylococcus aureus isolates from 64 ewes. Results and conclusion S. aureus was recovered from 65.3% of 547 clinically affected mammary glands, coagulase-negative staphylococci from 2.9%, enterobacteria, mainly Escherichia coli, from 7.3%, Streptococcus spp. from 4.6%, Mannheimia haemolytica from 1.8% and various other bacteria from 4.9%, while no bacteria were cultured from 13.2% of the samples. Forty percent of the ewes with unilateral clinical S. aureus mastitis also had a subclinical S. aureus infection in the other mammary gland. Twenty-four of 28 (86% pairs of S. aureus isolates obtained from clinically and subclinically affected mammary glands of the same ewe were indistinguishable by PFGE. The number of identical pairs was significantly greater than expected, based on the distribution of different S. aureus types within the flocks. One-third of the cases occurred during the first week after lambing, while a second peak was observed in the third week of lactation. Gangrene was present in 8.8% of the clinically affected glands; S. aureus was recovered from 72.9%, Clostridium perfringens from 6.3% and E. coli from 6.3% of the secretions from such glands. This study shows that S. aureus predominates as a cause of clinical ovine mastitis in Norway, also in very severe cases. Results also indicate that S. aureus is frequently spread between udder halves of infected ewes.

  15. Clinical Epidemiology, Evidence Based Medicine and Good Clinical Practice Guidelines vs. Clinical Method?

    OpenAIRE

    Luis Alberto Corona Martínez; Mercedes Fonseca Hernández

    2009-01-01

    Evidence Based Medicine, as a trend or approach to the medical practice nowadays, and the use of Good Clinical Practice Guidelines in the assistance activities are core elements that contribute to improve the professional practice and the decision making process in diagnosis and therapy; but they do not substitute the professional method for patients assistance: the clinical method. The purpose of this article is to analyze the role of clinical epidemiology, evidence based medicine and good c...

  16. Clinical Wisdom among Proficient Nurses

    DEFF Research Database (Denmark)

    Uhrenfeldt, Lisbeth; Hall, Elisabeth

    2007-01-01

    This paperexamines clinical wisdom which has emerged from a broader study anout nurse managers´influence on proficient registered nurse turnover and retention. The purpose of the study was to increase understanding of proficient nurses´experience and clinical practice by giving voice to the nurses...

  17. Two Approaches to Clinical Supervision.

    Science.gov (United States)

    Anderson, Eugene M.

    Criteria are established for a definition of "clinical supervision" and the effectiveness of such supervisory programs in a student teaching context are considered. Two differing genres of clinical supervision are constructed: "supervision by pattern analysis" is contrasted with "supervision by performance objectives." An outline of procedural…

  18. Role Modeling for Clinical Educators.

    Science.gov (United States)

    Ettinger, Ellen Richter

    1991-01-01

    To become better role models, higher educators in institutions of clinical education should be conscious of the behaviors they demonstrate and the broad range of activities and attitudes that students observe and emulate, including clinical competence, professional demeanor, doctor-patient interactions, ethical values, and social consciousness.…

  19. Clinical reasoning as social deliberation

    DEFF Research Database (Denmark)

    2014-01-01

    In this paper I will challenge the individualistic model of clinical reasoning. I will argue that sometimes clinical practice is rather machine-like, and information is called to mind and weighed, but the clinician is not just calculating how to use particular means to reach fixed ends. Often the...

  20. Clinical Service of Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The clinical practice of traditional Chinese medicine (TCM) faces three major challenges:(1)How to enhance its contribution on overall medical service quality? (2) How to best address the unmet medical needs in the contemporary society? (3)How to guarantee that the traditional perspective for disease diagnosis and treatment not be neglected in clinical practice?

  1. Mindfulness Meditation in Clinical Practice

    Science.gov (United States)

    Salmon, Paul; Sephton, Sandra; Weissbecker, Inka; Hoover, Katherine; Ulmer, Christi; Studts, Jamie L.

    2004-01-01

    The practice of mindfulness is increasingly being integrated into contemporary clinical psychology. Based in Buddhist philosophy and subsequently integrated into Western health care in the contexts of psychotherapy and stress management, mindfulness meditation is evolving as a systematic clinical intervention. This article describes…

  2. Clinical application of pet

    Directory of Open Access Journals (Sweden)

    Francisco Lomeña

    2005-10-01

    Full Text Available Positron emission tomography (PET is an imaging modality that gives information on tissue metabolism and functionalism, different from other imaging techniques like computed tomography (CT and magnetic resonance imaging (MRI, which provide anatomical or structural information. PET has reached its development in biomedical research because of its capacity to use analogous compounds of many endogenous substance as tracers, and to measure, in vivo and in a non-invasive way, their consumption by the different organs and tissues of the mammalian body. Fluordeoxyglucose-F18 (FDG PET has been proven to be a tracer adequate for clinical use in oncology and in many neurological diseases, with an excellent cost-efficiency ratio. The current PET-CT scanners can come to be the best tools for exploring patients who suffer from cancer.A tomografia por emissão de pósitrons (PET é uma técnica de diagnóstico por imagem que fornece informação sobre o metabolismo e funcionamento dos tecidos, diferente de outras técnicas de imagens como tomografia computadorizada (TC e ressonância magnética (RM, as quais fornecem informações estruturais ou anatômicas. O PET alcançou seu desenvolvimento em investigação biomédica devido à sua capacidade de usar traçadores análogos a muitas substâncias endógenas e de medir in vivo e de forma não invasiva seu consumo em diferentes órgãos e tecidos dos mamíferos 18Fluordesoxiglicose (FDG PET tem provado ser uma exploração de uso clínico com excelente relação custo benefício em oncologia e em muitas doenças neurológicas. Os atuais tomógrafos por PET-CT podem chegar a ser a melhor ferramenta de diagnóstico nos pacientes que sofrem de câncer.

  3. Clinical pharmacokinetics of molsidomine.

    Science.gov (United States)

    Rosenkranz, B; Winkelmann, B R; Parnham, M J

    1996-05-01

    Molsidomine is a prodrug for the formation of nitric oxide (NO). Its pharmacokinetics are characterised by rapid absorption and hydrolysis, taking a short time to achieve maximal systemic concentrations of both the parent compound and its active metabolite, SIN-1. The time to peak plasma drug concentration (tmax) is 1 to 2 hours. The bioavailability of the parent compound after oral administration in tablet form is 44 to 59%, but further metabolism to release NO and form polar metabolites is rapid; the half-life (t-1/2) of SIN-1 is 1 to 2 hours. Urinary excretion accounts for more than 90% of the part of the administered dose of molsidomine which is not excreted unchanged. Protein binding of the parent compound is very low (3 to 11%) and its volume of distribution (Vd) corresponds to the range of bodyweight. Single-dose studies (1, 2 and 4 mg) have revealed linear pharmacokinetics, and multiple dose studies in healthy individuals (2 mg 3 times daily for 7 days) and coronary artery disease (CAD) patients (4 mg 4 times daily for 4 weeks) do not show any accumulation of the drug. A study in young and elderly individuals indicated that the first-pass effect is decreased and t-1/2 prolonged with age, resulting in an increased area under the concentration-time curve (AUC) of molsidomine and SIN-1. In patients with liver disease and congestive heart failure similar changes were observed, but much less so in patients with CAD. Clearance was also impaired in patients with liver disease, but the pharmacokinetics of molsidomine were not markedly altered by impaired renal function. In general, due to a large therapeutic dose range, dosage adjustments are not required on the basis of clinical experience. In certain patients a lower starting dose may be recommended, such as in those with impaired liver or kidney function, in congestive heart failure or in the presence of concomitant treatment with other vasoactive compounds. A linear dose-effect relationship is observed with

  4. Clinical Observation on Hyperthyroidism

    International Nuclear Information System (INIS)

    A clinical analysis was made on 161 cases of hyperthyroidism seen at the Radioisotope Laboratory of Kyungpook National University Hospital. This series consisted of 144 cases of diffuse goiter and 17 cases of nodular goiter. 1) Hyperthyroidism was most prevalent in the 4th decade and male to female ratio was 1 : 4.6. 2) Cardinal symptoms in the order of frequency were weakness, easy fatigability, palpitation, weight loss, nervousness, perspiration, heat intolerance, increased appetite, insomnia and dysmenorrhoea. 3) Major physical findings in the order of frequency were goiter, fine tremor, tachycardia, wide pulse pressure, emaciation, warm moist skin, exophthalmos, systolic hypertension and atrial fibrillation. 4) The complications were ophthalmopathy (34.2%), thyrotoxic heart disease (5.6%), thyroid crisis (1 case), pretibial myxedema (1 case) and thyrotoxic myopathy (1 case). 5) Mean values of the six hour and twenty-four hour 131I uptakes by the thyroid glands were 67.5% and 71.6%, respectively, in diffuse goiter and 64.5% and 65.0%, respectively, in nodular goiter. 6) Mean values of twenty-four PB131I conversion ratio were 76.3% in diffuse goiter and 70.2% in nodular goiter and those of the basal metabolic rate was +51% in the former and +41% in the latter. Mean serum cholesterol level was 152 mg% in diffuse goiter and that in nodular goiter was 175 mg%. 7) Among the 134 cases treated with 131I, 66 cases (49.3%) were successfully controlled with single dose and in the majority of the cases the initial therapeutic dose required was 4.1-4.0 mC in diffuse goiter and 5.1-6.0 mC in nodular goiter. 8) With 131I treatment the symptoms improved in the following order: heat intolerance, emaciation, nervousness, insomnia, easy fatigability, weakness, fine tremor, goiter, perspiration, exertional dyspnea and palpitation. And in a few cases improvement of even exophthalmos was seen. 9) Following 131I treatment myxedema occurred in 4 cases (3%) and reoccurrence in 9 cases

  5. Clinical pharmacokinetics of dapsone.

    Science.gov (United States)

    Zuidema, J; Hilbers-Modderman, E S; Merkus, F W

    1986-01-01

    Dapsone (DDS) has for about 4 decades been the most important antileprosy drug. Concentrations of dapsone and its monoacetyl metabolite, MADDS, can be determined in biological media by high-performance liquid chromatography. After oral administration, the drug is slowly absorbed, the maximum concentration in plasma being reached at about 4 hours, with an absorption half-life of about 1.1 hours. However, the extent of absorption has not been adequately determined. The elimination half-life of dapsone is about 30 hours. The drug shows linear pharmacokinetics within the therapeutic range and the time-course after oral administration fits a 2-compartment model. The concentration-time profile of dapsone after parenteral administration is reviewed. Of clinical importance is the development of a new long acting injection, which permits monthly supervised administration as recommended by the World Health Organization. Following dapsone injection in gluteal subcutaneous adipose tissue, a sufficiently sustained absorption for this purpose has been reported. Dapsone is about 70 to 90% protein bound and its monoacetylated metabolite (MADDS) is almost completely protein bound. The volume of distribution of dapsone is estimated to be 1.5 L/kg. It is distributed in most tissues, but M. leprae living in the Schwann cells of the nerves might be unaffected. Dapsone crosses the placenta and is excreted in breast milk and saliva. Dapsone is extensively metabolised. Dapsone, some MADDS and their hydroxylated metabolites are found in urine, partly conjugated as N-glucuronides and N-sulphates. The acetylation ratio (MADDS:dapsone) shows a genetically determined bimodal distribution and allows the definition of 'slow' and 'rapid' acetylators. As enterohepatic circulation occurs, the elimination half-life of dapsone is markedly decreased after oral administration of activated charcoal. This permits successful treatment in cases of intoxication. The daily dose of dapsone in leprosy is 50 to

  6. Clinical Governance: Costs and Benefits

    Directory of Open Access Journals (Sweden)

    Kieran Walsh

    2014-04-01

    Full Text Available Dear Editor, Ravaghi et al. should be congratulated for offering a fascinating insight into the views of senior managers on the implementation of clinical governance (1. Clearly many had experience of challenges in implementation and there were different types of challenges. However, a common theme ran through many of the challenges, and that theme is one of cost. The managers did not mention cost explicitly but the issue was clearly implicit. They spoke of the need for more resources, support and staff engagement—all of which are associated with costs. We would do well to ask outright: what are the costs of implementing clinical governance? Such costs are likely to be significant, and are likely to be made up of all the components of clinical governance including, as the authors outline, “clinical effectiveness, clinical audit, risk management, patient and public involvement, education and training, staff management, and use of information” (2.

  7. Clinical polymorphism of endocrine ophthalmopathy

    Directory of Open Access Journals (Sweden)

    V. G. Likhvantseva

    2014-07-01

    Full Text Available Purpose: to analyze clinical polymorphism of endocrine ophthalmopathy in patients with Graves’ disease.Methods: Clinical and radiological data of 18 cases with clinical manifestations of lacrimal gland increase were analyzed and compared with data retrieved from 50 patients without increasing of lacrimal gland.Results: the characteristics of clinical manifestations of endocrine ophthalmopathy with lacrimal gland increase were presented. this form differs, as the organ of the target, along with orbital fat and/or eye muscles becomes the glandula lacrimalis. A correlation between fact involving, on the one hand, and the intensity and severity of the autoimmune process in orbit, on the other hand were identified.Conclusion: Involvement of this secretion organ in the autoimmune process makes the clinical course of endocrine ophthalmopa-thy more complicated, and leads to eye dry syndrome creation.

  8. Patient records and clinical overview

    DEFF Research Database (Denmark)

    Jensen, Lotte Groth

    2016-01-01

    investigate the creation of overview in daily clinical practice and further investigates how respectively a paper-based patient record and an EPR supports the creation of clinical overview. That the change from paper-based patient record to EPR can cause difficulties, interruptions and challenges...... or rendered visible in detail. Studies have been conducted on the differences on using respectively a paper-based patient record and an EPR, but few studies have focused on the creation of overview in daily clinical practice in connection with this transition. Therefore, the aim of this PhD dissertation...... of clinical overview. Considering the change from paper-based patient record to EPR, the dissertation also investigates how the two artefacts support the creation of clinical overview. The present dissertation is primarily based on ethnographic inspired observational studies and semi-structured interviews...

  9. Towards clinical bioethics (or a return to clinical ethics?).

    Science.gov (United States)

    Petrini, C

    2013-01-01

    Medical ethics has traditionally been oriented towards the clinical setting. Since the middle of the last century, however, various circumstances (associated mainly, though not exclusively, with rapid advances in technology and knowledge) have considerably broadened both the field of enquiry and the scope of this discipline. This is due partly to the overlap between medical ethics and bioethics, which in recent decades has acquired its own identity and concerns a multitude of ethical aspects in the biomedical field. Clinical ethics taps into the vast wealth of deontology, so that it has no need for additional criteria or principles, or for the definition of new values: rather, it recognizes the need to apply existing criteria, principles and values to contingent circumstances and contexts. A special role is reserved for ethics committees and, above all, for clinical ethics consultants, although in some countries the former are concerned mainly with authorisations for clinical trials. Clinical ethics consultants, however, may have a more incisive influence in clinical decisions: the special requisites and skills they need have been defined and discussed in various documents which are mentioned briefly in the present article. The presence of these consultants does not exonerate clinical physicians from their responsibilities or from liability for their decisions, in the formation of which they must refer constantly to codes of professional ethics. PMID:24424236

  10. Biodegradable polymers in clinical use and clinical development

    CERN Document Server

    Domb, Abraham J

    2011-01-01

    The definitive guide to biodegradable polymer science-where we are and what's to come The most comprehensive review of biodegradable polymers already utilized or under development for clinical use, Biodegradable Polymers in Clinical Use and Clinical Development looks at the state of biodegradable polymers now and over the next five years. Implantable molecules that break down within the body over a predetermined period of time, biodegradable polymers have been employed as drug carriers, orthopedic fixation devices, and absorbable sutures. Yet while hundreds of such polymers have been deve

  11. Clinical outcomes in clinical trials of anti-HIV treatment

    DEFF Research Database (Denmark)

    Reekie, J; Mocroft, A; J, Neaton; Lundgren, Jens Dilling

    2007-01-01

    Since the introduction of combination antiretroviral therapy, there has been a decrease in both AIDS-defining illnesses and deaths. This decrease meant that performing clinical trials with clinical outcomes in HIV infection became more time consuming and hence costly. Improved understanding and...... the infection, so when treatment is started it is currently a lifelong commitment. Is it reasonable then that guidelines are based almost completely on short-term randomized trials and observational studies of surrogate markers, or is there still a need for trials with clinical outcomes?...

  12. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... Topics News & Resources Intramural Research Public Health Topics Education & Awareness Resources Contact The Health Information Center Health ... Systematic Evidence Reviews & Clinical Practice Guidelines Resources Continuing Education Researchers Funding Training & Career Development Division of Intramural ...

  13. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... Topics News & Resources Intramural Research Public Health Topics Education & Awareness Resources Contact The Health Information Center Health ... Systematic Evidence Reviews & Clinical Practice Guidelines Resources Continuing Education ... Funding Training & Career Development Division of Intramural ...

  14. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... children's health with the goal to develop treatments, drugs, and devices specific to children. Resources for a Wide Range of Audiences The Children and Clinical ... and Postcards ...

  15. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... Clinical Studies Children have often had to accept medicines and treatments based on what is known to ... children's health with the goal to develop treatments, drugs, and devices specific to children. Resources for a ...

  16. Binge eating disorder: from clinical research to clinical practice.

    Science.gov (United States)

    Goracci, Arianna; Casamassima, Francesco; Iovieno, Nadia; di Volo, Silvia; Benbow, Jim; Bolognesi, Simone; Fagiolini, Andrea

    2015-01-01

    This case report describes the clinical course of a young woman suffering from binge eating disorder (BED) associated with obesity. It illustrates the efficacy of different medications in the treatment of BED and related conditions and is followed by the comments and clinical observations of 2 practicing psychiatrists. The issues described in this paper have important clinical implications and are topical, given that BED is now recognized as a specific disorder in the new Diagnostic and Statistical Manual of Mental Disorders, fifth edition classification system, but neither the US Food and Drug Administration nor any other regulatory agency has yet approved a drug for treatment of this disease, despite its very prevalent and disabling nature. Growing evidence from the fields of psychopathology and neurobiology, including preclinical and clinical studies, converges to support the idea that "overeating" has much in common with other behavioral addictions, and substance abuse treatment agents may show promise for the treatment of BED. PMID:25629882

  17. Creating clinical trial designs that incorporate clinical outcome assessments.

    Science.gov (United States)

    Gilbert, Mark R; Rubinstein, Lawrence; Lesser, Glenn

    2016-03-01

    Clinical outcome assessments (COAs) are increasingly being used in determining the efficacy of new treatment regimens. This was typified in the recent use of a symptom-based instrument combined with an organ-based measure of response for the approval of ruxolitinib in myelofibrosis. There are challenges in incorporating these COAs into clinical trials, including designating the level of priority, incorporating these measures into a combined or composite endpoint, and dealing with issues related to compliance and interpretation of results accounting for missing data. This article describes the results of a recent panel discussion that attempted to address these issues and provide guidance to the incorporation of COAs into clinical trials, including novel statistical designs, so that the testing of new treatments in patients with cancers of the central nervous system can incorporate these important clinical endpoints. PMID:26989129

  18. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... NHLBI Entire Site Health Topics News & Resources Intramural Research Public Health Topics Education & Awareness Resources Contact The ... Researchers Funding Training & Career Development Division of Intramural Research Research Resources Research Meeting Summaries Technology Transfer Clinical ...

  19. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... Awareness Resources Contact The Health Information Center Health Professionals Systematic Evidence Reviews & Clinical Practice Guidelines Resources Continuing Education Researchers Funding Training & Career Development Division of Intramural Research Research Resources Research Meeting ...

  20. ESR Perspective on Clinical Audit

    Directory of Open Access Journals (Sweden)

    Maurizio Centonze

    2011-05-01

    Full Text Available In October 2009, the European Commission published"nguidelines (Radiation Protection No. 159 on Clinical"nAudit for medical radiology-including Diagnostic"nRadiology, Nuclear Medicine and Radiotherapy-in"norder to improve the implementation of article 6.4 of"nthe Council Directive 97/43/ EURATOM, on health"nprotection of individuals against the dangers of ionizing"nradiation in relation to medical exposure. In article 6.4"nit is stated that "Clinical Audits shall be carried out"nin accordance with national procedures". However,"nthere is a wide variation in the understanding and"nimplementation of Clinical Audit in Europe and"nworldwide. The interpretation of the term audit and"nits differentiation from regulation, quality assurance,"naccreditation and research also differs across Europe."nIn January 2010, the Audit & Standards Subcommittee"nof the European Society of Radiology (ESR published"na document on the ESR perspective on Clinical Audit"nin an effort to define the scope of Clinical Audit in a"nway applicable across the European member states and"nradiological organizations."nThe aim of the presentation is to provide a"ncomprehensive outline of ESR perspective on the"naudit process for clinical radiologists and clinical"nradiology departments. The philosophy discussed is"nequally appropriate for interventional and diagnostic"nradiologists.

  1. Social media in clinical trials.

    Science.gov (United States)

    Thompson, Michael A

    2014-01-01

    Social media has potential in clinical trials for pointing out trial issues, addressing barriers, educating, and engaging multiple groups involved in cancer clinical research. Social media is being used in clinical trials to highlight issues such as poor accrual and barriers; educate potential participants and physicians about clinical trial options; and is a potential indirect or direct method to improve accrual. We are moving from a passive "push" of information to patients to a "pull" of patients requesting information. Patients and advocates are often driving an otherwise reluctant health care system into communication. Online patient communities are creating new information repositories. Potential clinical trial participants are using the Twittersphere and other sources to learn about potential clinical trial options. We are seeing more organized patient-centric and patient-engaged forums with the potential to crowd source to improve clinical trial accrual and design. This is an evolving process that will meet many individual, institutional, and regulatory obstacles as we move forward in a changed research landscape. PMID:24857086

  2. Clinical audit of a specialist symptomatic breast clinic.

    OpenAIRE

    Gui, G. P.; Allum, W. H.; Perry, N. M.; Wells, C.A.; Curling, O. M.; McLean, A; Oommen, R.; Sullivan, M.; Denton, S; Carpenter, R.

    1995-01-01

    The efficient delivery of health care requires vigilant quality assurance. We describe the audit of our symptomatic breast clinic, which includes the option of a one-stop diagnostic service. A total of 134 new and 386 follow-up patients attended over four consecutive clinics. The majority of new referrals (68%) were seen by a consultant surgeon. Urgent referrals were seen significantly sooner than routine referrals (P < 0.001, chi 2-test), and the mean wait from designated appointment to seei...

  3. Family therapy and clinical psychology

    OpenAIRE

    Carr, Alan

    1995-01-01

    The results of a survey of 111 clinical psychologists in the Republic of Ireland along with some comparable data from US and UK surveys were used to address a series of questions about the link between family therapy and clinical psychology. Family therapy was not a clearly identifiable sub-specialty within clinical psychology in Ireland. Family therapy theoretical models were used by more than a quarter of the Irish sample to conceptualize their work but by less than a tenth of US and UK res...

  4. Inquiry Teaching in Clinical Periodontics.

    Science.gov (United States)

    Heins, Paul J.; Mackenzie, Richard S.

    1987-01-01

    An adaptation of the inquiry method of teaching, which develops skills of information retrieval and reasoning through systematic questioning by the teacher, is proposed for instruction in clinical periodontics. (MSE)

  5. American Society of Clinical Oncology

    Science.gov (United States)

    ... Media Policy Sponsor Policy Terms of Use American Society of Clinical Oncology Genitourinary Cancers Symposium Call for ... or cosponsored by ASCO View Event 13th Asian Society for Neuro-Oncology (ASNO) Meeting/9th COGNO Annual ...

  6. Clinical leaders of the future.

    Science.gov (United States)

    Pearce, Lynne

    2016-08-10

    Putting ideas for management improvement into practice is one of the core tenets of the RCN's clinical leadership programme It's a transformational experience,' says RCN interim head of education Anne Corrin. 'The change is personal and professional.' PMID:27507391

  7. Checklist for clinical readiness published

    Science.gov (United States)

    Scientists from NCI, together with collaborators from outside academic centers, have developed a checklist of criteria to evaluate the readiness of complex molecular tests that will guide decisions made during clinical trials. The checklist focuses on tes

  8. American Society for Clinical Pathology

    Science.gov (United States)

    ... With the National Cancer Institute for Inaugural Global Pathology Conference March 2016 OneLab Memo ASCP Action Alert - ... 2016 Copyright © 2016 by American Society for Clinical Pathology. All Rights Reserved. Terms of Use About ASCP ...

  9. Neurofibromatosis: part 2--clinical management.

    Science.gov (United States)

    Batista, Pollyanna Barros; Bertollo, Eny Maria Goloni; Costa, Danielle de Souza; Eliam, Lucas; Cunha, Karin Soares Gonçalves; Cunha-Melo, José Renan; Darrigo Junior, Luiz Guilherme; Geller, Mauro; Gianordoli-Nascimento, Ingrid Faria; Madeira, Luciana Gonçalves; Mendes, Hérika Martins; Miranda, Débora Marques de; Mata-Machado, Nikolas Andre; Morato, Eric Grossi; Pavarino, Érika Cristina; Pereira, Luciana Baptista; Rezende, Nilton Alves de; Rodrigues, Luíza de Oliveira; Sette, Jorge Bezerra Cavalcanti

    2015-06-01

    Part 1 of this guideline addressed the differential diagnosis of the neurofibromatoses (NF): neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2) and schwannomatosis (SCH). NF shares some features such as the genetic origin of the neural tumors and cutaneous manifestations, and affects nearly 80 thousand Brazilians. Increasing scientific knowledge on NF has allowed better clinical management and reduced rate of complications and morbidity, resulting in higher quality of life for NF patients. Most medical doctors are able to perform NF diagnosis, but the wide range of clinical manifestations and the inability to predict the onset or severity of new features, consequences, or complications make NF management a real clinical challenge, requiring the support of different specialists for proper treatment and genetic counseling, especially in NF2 and SCH. The present text suggests guidelines for the clinical management of NF, with emphasis on NF1. PMID:26083891

  10. Clinical Decision Support (CDS) Inventory

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Clinical Decision Support (CDS) Inventory contains descriptions of past and present CDS projects across the Federal Government. It includes Federal projects,...

  11. A review of clinical guidelines.

    LENUS (Irish Health Repository)

    Andrews, E J

    2012-02-03

    BACKGROUND: Clinical guidelines are increasingly used in patient management but few clinicians are familiar with their origin or appropriate application. METHODS: A Medline search using the terms \\'clinical guidelines\\' and \\'practice guidelines\\' was conducted. Additional references were sourced by manual searching from the bibliographies of articles located. RESULTS AND CONCLUSION: Clinical guidelines originated in the USA in the early 1980s, initially as a cost containment exercise. Significant improvements in the process and outcomes of care have been demonstrated following their introduction, although the extent of improvement varies considerably. The principles for the development of guidelines are well established but many published guidelines fall short of these basic quality criteria. Guidelines are only one aspect of improving quality and should be used within a wider framework of promoting clinical effectiveness. Understanding their limitations as well as their potential benefits should enable clinicians to have a clearer view of their place in everyday practice.

  12. Responsibility of the clinical physicist

    International Nuclear Information System (INIS)

    The author discusses the various aspects of the responsibilities of physicians and clinical physicists with regard to radiation protection in medical applications of ionizing radiation. He annotates that in the Netherlands only 4 registered clinical physicists find a full-time task in x-ray diagnostics. Much more often it concerns a part-time task. the Dutch Society for Nuclear Medicine therefore recommends a legal basis for responsibilities of the clinical physicists and for taking up the appropriate discipline in the BIG-law. Also in this respect the society pleads for bringing into level of the number of qualified clinical physicists needed. The institutes involved should be obliged legally to acquire the necessary experts and should therefore dispose of the proper financial resources. (author)

  13. The clinical management of hyponatraemia.

    Science.gov (United States)

    Williams, David M; Gallagher, Maire; Handley, Joel; Stephens, Jeffrey W

    2016-07-01

    Hyponatraemia is the most common electrolyte disorder seen in clinical practice and the consequences can range from minor symptoms to life-threatening complications including seizures and cardiorespiratory distress. These effects occur as a result of fluid shifts due to deranged serum tonicity and subsequent cerebral oedema. The appropriate assessment and management of patients with hyponatraemia is not always achieved in clinical practice, which is partly related to challenges in teaching with limited clinical guidance. Recently, the European Society of Endocrinology, European Society of Intensive Care Medicine and European Renal Association-European Dialysis and Transplant Association produced clinical practice guidelines to focus on appropriate investigation and management of these patients. Within this manuscript, we highlight the key points from these guidelines, which are most pertinent to doctors of all specialties to improve the care of patients with this common electrolyte disorder. PMID:27044859

  14. [Research activity in clinical biochemistry

    DEFF Research Database (Denmark)

    Jorgensen, H.L.; Larsen, B.; Ingwersen, P.;

    2008-01-01

    BACKGROUND: Quantitative bibliometric measurements of research activity are frequently used, e.g. for evaluating applicants for academic positions. The purpose of this investigation is to assess research activity within the medical speciality of Clinical Biochemistry by comparing it with a matched...... Clinical Biochemistry, 57 fulfilled the inclusion criteria. Each of these 57 was matched according to medical title with two randomly chosen specialists from other specialities, totaling 114. Using Medline and the Web of Science, the number of publications and the number of citations were then ascertained....... RESULTS: 25% of the 11,691 specialists held a PhD degree or doctoral degree, DMSci, (Clinical Biochemistry: 61%). The 171 specialists included in the study had 9,823 papers in Medline and 10,140 papers in the Web of Science. The number of Medline papers per specialist was 71 for Clinical Biochemistry...

  15. CLINICAL ASPECTS OF VETERINARY LISTERIOSIS

    Science.gov (United States)

    This invited presentation updates the clinical aspects of Listeria monocytogenes in food animals. It summarizes the epidemiology and diagnostic methods. Virtually all domesticated animal species are susceptible to listeric infection, with a large proportion of healthy asymptomatic animals shedding...

  16. Clinical Information Support System (CISS)

    Data.gov (United States)

    Department of Veterans Affairs — Clinical Information Support System (CISS) is a web-based portal application that provides a framework of services for the VA enterprise and supplies an integration...

  17. Types of Treatment: Clinical Trials

    Science.gov (United States)

    ... Previous Article Palliative Care Next Article How a Clinical Trial Works Follow us Subscribe to a newsletter This field is required ... Fundraising Disclosure Refund Policy Work for LLS Contact Us Email Subscription Center

  18. Clinical Biomarkers for Hypoxia Targeting

    OpenAIRE

    Le, Quynh-Thu; Courter, Don

    2008-01-01

    Tumor hypoxia or a reduction of the tissue oxygen tension is a key microenvironmental factor for tumor progression and treatment resistance in solid tumors. Because hypoxic tumor cells have been demonstrated to be more resistant to ionizing radiation, hypoxia has been a focus of laboratory and clinical research in radiation therapy for many decades. It is believed that proper detection of hypoxic regions would guide treatment options and ultimately improve tumor response. To date, most clinic...

  19. Oral cysticercosis: a clinical dilemma

    OpenAIRE

    Wanjari, Sangeeta Panjab; Patidar, Kalpana A; Parwani, Rajkumar N; Satyajitraje A Tekade

    2013-01-01

    Cysticercosis is a potentially fatal parasitic disease caused by cysticercus cellulosae, the larval stage of Taenia solium. Oral cysticercosis is a rare entity and represents difficulty in clinical diagnosis. This article reports two cases of oral cysticercosis involving buccal and labial mucosa. Both the cases presented with solitary, nodular swelling that had been clinically diagnosed as a mucocele. Histopathology of excisional biopsy revealed it to be cysticercosis. Single, cystic nodular ...

  20. Recombinant erythropoietin in clinical practice

    OpenAIRE

    Ng, T; Marx, G.; Littlewood, T; Macdougall, I

    2003-01-01

    The introduction of recombinant human erythropoietin (RHuEPO) has revolutionised the treatment of patients with anaemia of chronic renal disease. Clinical studies have demonstrated that RHuEPO is also useful in various non-uraemic conditions including haematological and oncological disorders, prematurity, HIV infection, and perioperative therapies. Besides highlighting both the historical and functional aspects of RHuEPO, this review discusses the applications of RHuEPO in clinical practice a...

  1. Clinical services for sleep disorders

    OpenAIRE

    Stores, G; Wiggs, L.

    1998-01-01

    Children's sleep disorders are common and often harmful to development and well being. The clinical services available to affected children and their families need to be improved. At present, professional interest and expertise in sleep disorders medicine is severely limited by the paucity of appropriate teaching and training. The work of a mainly tertiary sleep disorders clinic was reviewed, which showed that accurate diagnosis of a wide range of sleep disorders is possible...

  2. Clinical relevance in anesthesia journals

    DEFF Research Database (Denmark)

    Lauritsen, Jakob; Møller, Ann M

    2006-01-01

    The purpose of this review is to present the latest knowledge and research on the definition and distribution of clinically relevant articles in anesthesia journals. It will also discuss the importance of the chosen methodology and outcome of articles.......The purpose of this review is to present the latest knowledge and research on the definition and distribution of clinically relevant articles in anesthesia journals. It will also discuss the importance of the chosen methodology and outcome of articles....

  3. Clinical psychology, sexuality and gender

    OpenAIRE

    Burns, J.; Zitz, C.

    2015-01-01

    Clinical psychology has an early ignominious past with regard to sexuality and gender. Burns and Zitz provide a history of the perspectives taken on sexuality, gender and their variants through the lens of clinical psychology, moving from an individualist, positivistic perspective to more current positions such as intersectionality and post-modern understandings of distress. Alongside this changing perspective the development of the profession and its therapeutic practices will be charted. B...

  4. Mammascintigraphy: fundamentals, protocols, clinical application

    International Nuclear Information System (INIS)

    Radiopharmaceuticals, methods and results of clinical application of mammascintigraphy are reviewed. The main advantage of mammascintigraphy is its higher (at least 90%) specificity in comparison with X-ray mammography, possibility of using it in patients with X-ray dense gland, predicting cancer metastases and follow-up of tumor regression during chemotherapy. Mammascintigraphy is an effective reliable method of accurate diagnosis of breast cancer, which should be introduced in clinical practice of Russian breast cancer control centers as soon as possible

  5. Data integration for clinical genomics

    OpenAIRE

    Calabria,, C.

    2011-01-01

    Genetics and Molecular Biology are keys for the understanding the mechanisms of many of the human diseases that have strong harmful effects. The empirical mission of Genetics is to translate these mechanisms into Clinical benefits, thus bridging in-silico findings to patient bed side: approaching this goal means achieving what is commonly referred as clinical genomics or personalized medicine. In this process, technologies are assuming an increasing role. With the introduction of new expe...

  6. Osteitis pubis: a clinical challenge *

    OpenAIRE

    DeFinney, John; Clements, David; Staines, Marilyn; Mior, Silvano

    1990-01-01

    Mechanical pain in the region of the groin poses an interesting and at times confusing clinical dilemma. This is especially true for osteitis pubis, an inflammatory condition affecting the symphysis pubis. Recently it has been recognized as a potential source of pain in athletes. In this report, we will review the typical presentation of osteitis pubis, including the clinical, examination and radiographic features of this condition. A proposed plan of management, based on previous work on avu...

  7. Clinical case of toxocariasis chorioretinitis

    Directory of Open Access Journals (Sweden)

    I. G. Pikhovskaia

    2014-07-01

    Full Text Available The clinical case of a toxocariasis chorioretinitis which is of interest for ophthalmologists is described. Insufficient knowledge of clinic and diagnostics of a lesion of eyes by Toxocara canis, their infrequent occurrence, similarity of the ophthalmologic picture with inflammatory diseases and eye neoplasms can be at the bottom of gross diagnostic mistake and wrong choice of treatment tactics.

  8. Malaria Diagnostics in Clinical Trials

    OpenAIRE

    Murphy, Sean C.; Shott, Joseph P.; Parikh, Sunil; Etter, Paige; Prescott, William R.; Stewart, V. Ann

    2013-01-01

    Malaria diagnostics are widely used in epidemiologic studies to investigate natural history of disease and in drug and vaccine clinical trials to exclude participants or evaluate efficacy. The Malaria Laboratory Network (MLN), managed by the Office of HIV/AIDS Network Coordination, is an international working group with mutual interests in malaria disease and diagnosis and in human immunodeficiency virus/acquired immunodeficiency syndrome clinical trials. The MLN considered and studied the wi...

  9. OBSTRUCTIVE JAUNDICE: A CLINICAL STUDY

    OpenAIRE

    Antony,; Rasool Syed

    2016-01-01

    BACKGROUND Jaundice is a frequent manifestation of biliary tract disorders and evaluation of obstructive jaundice is a common problem faced by general surgeons. Obstructive jaundice of varied aetiology is one of the main cause of hospital admissions. Hence, comprehensive study of aetiology, clinical presentation, management of obstructive jaundice is important in management of these patients. AIMS AND OBJECTIVES  Study the clinical history and presentation of obstructiv...

  10. CLINICAL OUTCOME MEASURES OF PSORIASIS

    OpenAIRE

    E. Berardesca; Bonifati, C

    2011-01-01

    Several tools have been introduced in clinical trials to quantify the severity and the response to a given therapeutic regimen of both psoriasis and psoriatic arthritis. Each method present specific advantages and limitations. Here we will discuss some of the most popular clinical outcome measures of both psoriasis (Psoriasis Severity Index, Physician Global Assessment, National Psoriasis Fundation-Psoriasis Score, Dermatology Life Quality Index) and psoriatic arthritis (American College Rheu...

  11. The Evaluation Of Clinical Competence

    OpenAIRE

    Boucher, François-Gilles; Palmer, Wilfred H.; Page, Gordon; Barriault, Ronald; Seely, Janet

    1980-01-01

    During a workshop on the evaluation of clinical competence, the participants identified the process skills that comprise clinical competence and examined the techniques available for evaluating these skills. No single technique allows satisfactory evaluation of all the process skills; the most commonly used methods (chart review and case presentation) evaluate few process skills. An adequate performance profile in all the process skills requires a combination of evaluation techniques. Medical...

  12. Quality Assessment for Clinical Proteomics

    OpenAIRE

    Tabb, David L.

    2012-01-01

    Proteomics has emerged from the labs of technologists to enter widespread application in clinical contexts. This transition, however, has been hindered by overstated early claims of accuracy, concerns about reproducibility, and the challenges of handling batch effects properly. New efforts have produced sets of performance metrics and measurements of variability that establish sound expectations for experiments in clinical proteomics. As researchers begin incorporating these metrics in a qual...

  13. Clinical databases in physical therapy.

    OpenAIRE

    Swinkels, I.C.S.; Ende, C.H.M. van den; Bakker, D.; Wees, Ph.J van der; Hart, D.L.; Deutscher, D.; Bosch, W.J.H. van den; Dekker, J.

    2007-01-01

    Clinical databases in physical therapy provide increasing opportunities for research into physical therapy theory and practice. At present, information on the characteristics of existing databases is lacking. The purpose of this study was to identify clinical databases in which physical therapists record data on their patients and treatments and to investigate the basic aspects, data sets, output, management, and data quality of the databases. Identification of the databases was performed by ...

  14. Ubiquitous Multicriteria Clinic Recommendation System.

    Science.gov (United States)

    Chen, Toly

    2016-05-01

    Advancements in information, communication, and sensor technologies have led to new opportunities in medical care and education. Patients in general prefer visiting the nearest clinic, attempt to avoid waiting for treatment, and have unequal preferences for different clinics and doctors. Therefore, to enable patients to compare multiple clinics, this study proposes a ubiquitous multicriteria clinic recommendation system. In this system, patients can send requests through their cell phones to the system server to obtain a clinic recommendation. Once the patient sends this information to the system, the system server first estimates the patient's speed according to the detection results of a global positioning system. It then applies a fuzzy integer nonlinear programming-ordered weighted average approach to assess four criteria and finally recommends a clinic with maximal utility to the patient. The proposed methodology was tested in a field experiment, and the experimental results showed that it is advantageous over two existing methods in elevating the utilities of recommendations. In addition, such an advantage was shown to be statistically significant. PMID:26984357

  15. Treatment process - Clinical decision making

    International Nuclear Information System (INIS)

    Full text: Although many aspects of cancer treatment, especially the technical aspects of radiotherapy, are subject to rigorous quality assurance, the quality of actual clinical decision making is rarely scrutinized. There are several developments over the past 10 to 15 years that have driven forward attempts in the UK National Health Service (NHS) to bring such quality assurance into the clinic. This goes back to the work of Dr. Archie Cochrane in the 1970s and his views that clinical practice should be underpinned by research evidence and only treatments that have been shown to be effective should be used. The term clinical effectiveness is now widely used. It refers to the amount by which any treatment actually affects outcomes for patients. For cancer patients this may mean 'cure', improving survival, local control, or symptoms, or minimizing toxicity - or indeed a combination of all of them. But how do we know what is the most effective treatment for a particular patient? How do we assure the quality of the clinical decision? By going to the research evidence and asking questions about whether there is clear evidence which treatment is likely to give the best outcome for this patient. This is 'evidence-based medicine': the application of the best available evidence from clinical care research to the management of individual patients. However this is not just a blind application of this evidence and is not 'cookbook medicine'. Other things need to be considered as well as the evidence, a clinical judgement about the applicability of any treatment to an individual patient and patient preference. When confronted by a patient with a clinical problem, how do we find the 'best' evidence? 1. Refine the clinical question into a standard format: patient, intervention, comparison, and outcomes (PICO) 2. Search for relevant publications in electronic databases, such as Pubmed and Medline, and retrieve them 3. Critically read and appraise them: Are they relevant to this

  16. 75 FR 57472 - Clinical Investigator Training Course

    Science.gov (United States)

    2010-09-21

    ... investigational medicine; Promote communication between clinical investigators and FDA; Enhance investigators... days in advance. SUPPLEMENTARY INFORMATION: Clinical trial investigators play a critical role in the... HUMAN SERVICES Food and Drug Administration Clinical Investigator Training Course AGENCY: Food and...

  17. Clinical Leadership: A Call to Action.

    Science.gov (United States)

    Grindel, Cecelia Gatson

    2016-01-01

    Clinical nurses are expected to assume leadership roles to enhance patient care and assure efficient work processes. Dimensions of clinical leadership and the essential knowledge and skills of the clinical leader are described. PMID:27044123

  18. Early Learner Engagement in the Clinical Workplace

    NARCIS (Netherlands)

    Chen, H.C.

    2015-01-01

    Introduction Recent calls for medical education reform advocate for the integration of knowledge with clinical experience through early clinical immersion. Yet, early learners rarely are invited to participate in workplace activities and early clinical experiences remain largely observational. We

  19. Nocardial mycetoma: Diverse clinical presentations

    Directory of Open Access Journals (Sweden)

    Sharma Nand

    2008-01-01

    Full Text Available Nocardia spp are gram-positive, aerobic, acid-fast bacteria which exist as saprophytes in nature. Invasive disseminated infections are particularly common in immunocompromised or debilitated hosts. Superficial infections with Nocardia spp occur as a result of local trauma and contamination of the wound. Clinically, it presents as acute infection (abscesses or cellulitis, mycetoma, or sporotrichoid infection. Differential diagnosis includes eumycetoma, chromomycosis, blastomycosis, coccidioidomycosis, sporotrichosis, tuberculosis, botryomycosis, syphilis, yaws, and neoplasia. Its diagnosis is confirmed by demonstrating the causative organism in exudates (as granules, tissue specimens, or cultures. Early diagnosis will obviate need for drastic surgical measures as early institution of chemotherapy is effective in most patients. However, its diagnosis is often delayed due to diverse clinical presentations and for want of clinical suspicion, particularly in non-endemic areas. This paper presents 4 clinical forms of this not so uncommon disease, emphasizing the importance of high index of clinical suspicion, especially in non-endemic regions; and the significance of repeated examination of exudates for Nocardia granules for an early diagnosis.

  20. Unusual clinical manifestations of leptospirosis

    Directory of Open Access Journals (Sweden)

    Bal A

    2005-01-01

    Full Text Available Leptospirosis has protean clinical manifestations. The classical presentation of the disease is an acute biphasic febrile illness with or without jaundice. Unusual clinical manifestations may result from involvement of pulmonary, cardiovascular, neural, gastrointestinal, ocular and other systems. Immunological phenomena secondary to antigenic mimicry may also be an important component of many clinical features and may be responsible for reactive arthritis. Leptospirosis in early pregnancy may lead to fetal loss. There are a few reports of leptospirosis in HIV- infected individuals but no generalisation can be made due to paucity of data. It is important to bear in mind that leptospiral illness may be a significant component in cases of dual infections or in simultaneous infections with more than two pathogens.

  1. Pain assessment in clinical Rheumatology

    Directory of Open Access Journals (Sweden)

    L. Sinigaglia

    2011-09-01

    Full Text Available The diagnostic approach in clinical practice in Rheumatology is mainly based on the recognition of pain origin. Patient’s experience of pain may be similar in different diseases involving bones, joints, tendons, muscles or peripheral nervous system. The analysis of some characteristics of pain may be helpful in the diagnostic approach. In this perspective pain must be analyzed according to the type, localization, occurrence, elicitation and concomitant clinical signs. In the majority of cases this analysis allows a preliminary differential diagnosis which is essential to drive further assessments. The diagnostic approach to arthropaties is based on a group of indicative criteria which include diffusion of the arthropathy, the involved sites, the course of the joint disease, the joint damage, the history of preceding events and the presence of extra-articular features which accompany joint disease. This kind of clinical approach helps the clinician in saving time and reducing costs of diagnosis by driving any further investigation.

  2. Pediatric Obstructive Uropathy: Clinical Trials

    International Nuclear Information System (INIS)

    As the powerful tools of molecular biology continue to delineate new concepts of pathogenesis of diseases, new molecular-level therapeutic modalities are certain to emerge. In order to design and execute clinical trials to evaluate outcomes of these new treatment modalities, we will soon need a new supply of investigators with training and experience in clinical research. The slowly-progressive nature of chronic pediatric kidney disease often results in diagnosis being made at a time remote from initial result, and the inherently slow rate of progression makes changes difficult to measure. Thus, development of molecular markers for both diagnosis and rate of progression will be critical to studies of new therapeutic modalities. We will review general aspects of clinical trials and will use current and past studies as examples to illustrate specific points, especially as these apply to chronic kidney disease associated with obstructive uropathy in children. (author)

  3. Clinical development of Ebola vaccines.

    Science.gov (United States)

    Sridhar, Saranya

    2015-09-01

    The ongoing outbreak of Ebola virus disease in West Africa highlighted the lack of a licensed drug or vaccine to combat the disease and has renewed the urgency to develop a pipeline of Ebola vaccines. A number of different vaccine platforms are being developed by assessing preclinical efficacy in animal models and expediting clinical development. Over 15 different vaccines are in preclinical development and 8 vaccines are now in different stages of clinical evaluation. These vaccines include DNA vaccines, virus-like particles and viral vectors such as live replicating vesicular stomatitis virus (rVSV), human and chimpanzee adenovirus, and vaccinia virus. Recently, in preliminary results reported from the first phase III trial of an Ebola vaccine, the rVSV-vectored vaccine showed promising efficacy. This review charts this rapidly advancing area of research focusing on vaccines in clinical development and discusses the future opportunities and challenges faced in the licensure and deployment of Ebola vaccines. PMID:26668751

  4. MR spectroscopy in clinical research

    DEFF Research Database (Denmark)

    Henriksen, O

    1994-01-01

    MR spectroscopy (MRS) offers unique possibilities for non-invasive evaluation of biochemistry in vivo. During recent years there has been a growing body of evidence from clinical research studies on human beings using 31P and 1H MRS. The results indicate that it is possible to evaluate phosphorous...... energy metabolism, loss of neurones, and lactate production in a large number of brain diseases. Furthermore, 31P and 1H MRS may be particularly clinically useful in evaluation of various disorders in skeletal muscle. In the heart 31P MRS seems at the moment the most suitable for evaluation of global...... affections of the myocardium. In the liver 31P MRS appears to be rather insensitive and non-specific, but absolute quantification of metabolite concentrations and using metabolic "stress models" may prove useful in the future. The clinical role of MRS in oncology is still unclear, but it may be useful for...

  5. Clinical utility of curcumin extract.

    Science.gov (United States)

    Asher, Gary N; Spelman, Kevin

    2013-01-01

    Turmeric root has been used medicinally in China and India for thousands of years. The active components are thought to be the curcuminoids, primarily curcumin, which is commonly available worldwide as a standardized extract. This article reviews the pharmacology of curcuminoids, their use and efficacy, potential adverse effects, and dosage and standardization. Preclinical studies point to mechanisms of action that are predominantly anti-inflammatory and antineoplastic, while early human clinical trials suggest beneficial effects for dyspepsia, peptic ulcer, inflammatory bowel disease, rheumatoid arthritis, osteoarthritis, uveitis, orbital pseudotumor, and pancreatic cancer. Curcumin is well-tolerated; the most common side effects are nausea and diarrhea. Theoretical interactions exist due to purported effects on metabolic enzymes and transport proteins, but clinical reports do not support any meaningful interactions. Nonetheless, caution, especially with chemotherapy agents, is advised. Late-phase clinical trials are still needed to confirm most beneficial effects. PMID:23594449

  6. Clinical Decision Support Systems: A Useful Tool in Clinical Practice

    Directory of Open Access Journals (Sweden)

    Kolostoumpis G.

    2012-01-01

    Full Text Available The possibility of supporting in decision – making shows an increase in recent years. Based on mathematic simulation tools, knowledge databases, processing methods, medical data and methods, artificial intelligence for coding of the available knowledge and for resolving complex problems arising into clinical practice. Aim: the aim of this review is to present the development of new methods and modern services, in clinical practice and the emergence in their implementation. Data and methods: the methodology that was followed included research of articles that referred to health sector and modern technologies, at the electronic data bases “pubmed” and “medline”. Results: Is a useful tool for medical experts using characteristics and medical data used by the doctors. Constitute innovation for the medical community, and ensure the support of clinical decisions with an overall way by providing a comprehensive solution in the light of the integration of computational decision support systems into clinical practice. Conclusions: Decision Support Systems contribute to improving the quality of health services with simultaneous impoundment of costs (i.e. avoid medical errors

  7. Children and Clinical Studies: Why Clinical Studies Are Important

    Medline Plus

    Full Text Available ... E-Newsletters About NHLBI Organization NHLBI Director Budget, Planning, & Legislative Advisory Committees Contact Us FAQs Home » Clinical ... the general public. Last Updated: August 3, 2015 Resources Educational Website - English / Spanish Paper Kingdom Video ... and Postcards Facebook Page

  8. Clinical Scientists Improving Clinical Practices: In Thoughts and Actions

    Science.gov (United States)

    Apel, Kenn

    2014-01-01

    Purpose: In this article, the author comments on aspects of Kamhi's (2014) article, which caused the author to think more deeply about definitions of language, theories of learning, and how these two core components of intervention prepare clinical scientists as they search the literature for new knowledge. Interprofessional collaborative…

  9. Gatekeepers for pragmatic clinical trials.

    Science.gov (United States)

    Whicher, Danielle M; Miller, Jennifer E; Dunham, Kelly M; Joffe, Steven

    2015-10-01

    To successfully implement a pragmatic clinical trial, investigators need access to numerous resources, including financial support, institutional infrastructure (e.g. clinics, facilities, staff), eligible patients, and patient data. Gatekeepers are people or entities who have the ability to allow or deny access to the resources required to support the conduct of clinical research. Based on this definition, gatekeepers relevant to the US clinical research enterprise include research sponsors, regulatory agencies, payers, health system and other organizational leadership, research team leadership, human research protections programs, advocacy and community groups, and clinicians. This article provides a framework to help guide gatekeepers' decision-making related to the use of resources for pragmatic clinical trials. Relevant ethical considerations for gatekeepers include (1) concern for the interests of individuals, groups, and communities affected by the gatekeepers' decisions, including protection from harm and maximization of benefits; (2) advancement of organizational mission and values; and (3) stewardship of financial, human, and other organizational resources. Separate from these ethical considerations, gatekeepers' actions will be guided by relevant federal, state, and local regulations. This framework also suggests that to further enhance the legitimacy of their decision-making, gatekeepers should adopt transparent processes that engage relevant stakeholders when feasible and appropriate. We apply this framework to the set of gatekeepers responsible for making decisions about resources necessary for pragmatic clinical trials in the United States, describing the relevance of the criteria in different situations and pointing out where conflicts among the criteria and relevant regulations may affect decision-making. Recognition of the complex set of considerations that should inform decision-making will guide gatekeepers in making justifiable choices regarding

  10. Clinical applications of Gallium-68

    International Nuclear Information System (INIS)

    Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator. As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron on site. Gallium-68-labeled peptides have been recognized as a new class of radiopharmaceuticals showing fast target localization and blood clearance. 68Ga-DOTATOC, 8Ga-DOTATATE, 68Ga-DOTANOC, are the most prominent radiopharmaceuticals currently in use for imaging and differentiating lesions of various somatostatin receptor subtypes, overexpressed in many neuroendocrine tumors. There has been a tremendous increase in the number of clinical studies with 68Ga over the past few years around the world, including within the United States. An estimated ∼10,000 scans are being performed yearly in Europe at about 100 centers utilizing 68Ga-labeled somatostatin analogs within clinical trials. Two academic sites within the US have also begun to undertake human studies. This review will focus on the clinical experience of selected, well-established and recently applied 68Ga-labeled imaging agents used in nuclear medicine. - Highlights: ► A summary of the emerging clinical uses of 68Ga-based radiopharmaceuticals is provided. ► 68Ga-PET may prove as or more clinically robust than the corresponding 18F-labeled agents. ► 68Ga-radiopeptides were studied for targeting of somatostatin receptors subtypes. ► 68Ga-DOTATOC, 68Ga-DOTATATE, 68Ga-DOTANOC, are currently in clinical trials

  11. New developments in clinical CARS

    Science.gov (United States)

    Weinigel, Martin; Breunig, Hans Georg; Kellner-Höfer, Marcel; Bückle, Rainer; Darvin, Maxim; Lademann, Juergen; König, Karsten

    2013-02-01

    We combined two-photon fluorescence and coherent anti-Stokes Raman scattering (CARS) imaging in a clinical hybrid multiphoton tomograph for in vivo imaging of human skin. The clinically approved TPEF/CARS system provides simultaneous imaging of endogenous fluorophores and non-fluorescent lipids. The Stokes laser for the two-beam configuration of CARS is based on spectral broadening of femtosecond laser pulses in a photonic crystal fiber (PCF). We report on the highly flexible medical TPEF/CARS tomograph MPTflex®-CARS with an articulated arm and first in vivo measurements on human skin.

  12. Electrochemical Sensors for Clinic Analysis

    Directory of Open Access Journals (Sweden)

    Guang Li

    2008-03-01

    Full Text Available Demanded by modern medical diagnosis, advances in microfabrication technology have led to the development of fast, sensitive and selective electrochemical sensors for clinic analysis. This review addresses the principles behind electrochemical sensor design and fabrication, and introduces recent progress in the application of electrochemical sensors to analysis of clinical chemicals such as blood gases, electrolytes, metabolites, DNA and antibodies, including basic and applied research. Miniaturized commercial electrochemical biosensors will form the basis of inexpensive and easy to use devices for acquiring chemical information to bring sophisticated analytical capabilities to the non-specialist and general public alike in the future.

  13. Journal of Clinical Medicine Editorial

    Directory of Open Access Journals (Sweden)

    Jane M. Grant-Kels

    2012-12-01

    Full Text Available “Why yet another journal?” Because this new journal will be different in that we are not just about new information but about understanding new information. We are online, peer reviewed, with a quick turnaround time from submission to publication and without any limit regarding length! Therefore, I am honored to introduce the Journal of Clinical Medicine (JCM, which has been created to serve as a hub for disseminating new findings and discoveries in clinical medicine to clinicians and medical researchers worldwide. [...

  14. Clinical myths of forensic neuropsychology.

    Science.gov (United States)

    Greiffenstein, Manfred F

    2009-02-01

    Clinical myths and lore are unfounded beliefs that still influence practice decisions. I examine the validity of six beliefs commonly encountered in forensic neuropsychology practice: the admissibility of test batteries; avoidance of practice effects; forewarning insures good effort; average deficits in bright persons; 15% chronic impairment in mild brain injury; and examiner bias causing malingering. I show these beliefs are invalid because of material misunderstandings of case law and literature, falsification by empirical findings, and lack of authoritative sources. The benefits, costs, and persistence of clinical myths are discussed. PMID:18609338

  15. Mast cell tumors: clinical management

    International Nuclear Information System (INIS)

    Mast cell tumors are commonly diagnosed in small animal practice; however, appropriate treatment and prognosis remain controversial. These tumors are considered malignant in dogs but generally are benign in cats. Mast cell tumors are associated with various clinical signs that are related to the release of biologic mediators from the granules of the neoplastic cells, and these signs may be the primary presenting complaint. Clinical staging as well as histopathologic grading are important in determining the treatment of choice and prognosis. Treatment consists of several options, including surgery, radiation therapy, and chemotherapy. This article summarizes the available information regarding diagnosis, treatment, and prognosis of mast cell tumors and makes recommendations for therapy

  16. Positron emission tomography clinical practice

    CERN Document Server

    Valk, Peter E; Bailey, Dale L; Townsend, David W; Maisey, Michael N

    2006-01-01

    This book provides a contemporary reference to the science, technology and clinical applications of PET and PET/CT. The opening chapters summarize the scientific aspects of PET and PET/CT including physics, instrumentation, radiation dosimetry and radiation protection. A chapter on normal variants in FDG PET imaging serves as an introduction to the clinical chapters, which cover oncology applications and have been updated to include the impact of FDG PET/CT imaging in oncology. The book concludes with chapters on the use of PET and PET/CT in cardiology and neurology and PET imaging of infectio

  17. CLINICAL OUTCOME MEASURES OF PSORIASIS

    Directory of Open Access Journals (Sweden)

    E. Berardesca

    2011-09-01

    Full Text Available Several tools have been introduced in clinical trials to quantify the severity and the response to a given therapeutic regimen of both psoriasis and psoriatic arthritis. Each method present specific advantages and limitations. Here we will discuss some of the most popular clinical outcome measures of both psoriasis (Psoriasis Severity Index, Physician Global Assessment, National Psoriasis Fundation-Psoriasis Score, Dermatology Life Quality Index and psoriatic arthritis (American College Rheumatology response criteria, Psoriatic Arthritis Response Criteria. Key words: Psoriasis, psoriatic arthritis, outcome

  18. Clinical applications of cells labelling

    International Nuclear Information System (INIS)

    Blood cells labelled with radionuclides are reviewed and main applications are described. Red blood cell labelling by both random and specific principle. A table with most important clinical uses, 99mTc labelling of RBC are described pre tinning and in vivo reduction of Tc, in vitro labelling and administration of labelled RBC and in vivo modified technique. Labelled leucocytes with several 99mTc-complex radiopharmaceuticals by in vitro technique and specific monoclonal s for white cells(neutrofiles). Labelled platelets for clinical use and research by in vitro technique and in vivo labelling

  19. Age and Clinical Dengue Illness

    OpenAIRE

    Egger, Joseph R.; Paul G Coleman

    2007-01-01

    The relationship between age and risk for classic dengue fever has never been quantified. We use data from clinical patients to show that the relative risk of having classical disease after primary dengue virus infection increases with age. This relationship has implications for strategies aimed at controlling dengue fever.

  20. Digital clinical photography: Practical tips

    Directory of Open Access Journals (Sweden)

    Sharad Mutalik

    2010-01-01

    Full Text Available Photographs are the most preferred and easiest way of documentation of patient visual features. In aesthetic and cutaneous surgery, there is an increased need for proper photographic documentation, from a medicolegal view point. This article discusses the basic aspects of camera and photography which a dermatologist should be aware before he/she starts with clinical photography.

  1. Clinical Spectrum of Propionic Acidaemia

    Directory of Open Access Journals (Sweden)

    Muhammad Rafique

    2013-01-01

    Full Text Available Objectives. To evaluate the clinical features, physical findings, diagnosis, and laboratory parameters of the patients with propionic acidaemia (PA. Methods. The records of diagnosed cases of propionic acidaemia were reviewed, retrospectively. Results. Twenty-six patients with PA had 133 admissions. The majority (85% of the patients exhibited clinical manifestations in the 1st week of life. Regarding clinical features, lethargy, fever, poor feeding, vomiting, dehydration, muscular hypotonia, respiratory symptoms, encephalopathy, disturbance of tone and reflexes, and malnutrition were observed in 51–92% admissions. Metabolic crises, respiratory diseases, hyperammonaemia, metabolic acidosis, hypoalbuminaemia, and hypocalcaemia were observed in 30–96% admissions. Pancytopenia, ketonuria, hypoproteinemia, hypoglycaemia, and mildly disturbed liver enzymes were found in 12–41% admissions. Generalised brain oedema was detected in 17% and cerebral atrophy in 25% admissions. Gender-wise odd ratio analysis showed value of 1.9 for lethargy, 1.99 for respiratory diseases, 0.55 for anaemia, and 1.82 for hypocalcaemia. Conclusion. Propionic acidaemia usually presents with wide spectrum of clinical features and disturbances of laboratory parameters in early neonatal age. It is associated with significant complications which deteriorate the patients’ quality of life. Perhaps with early diagnosis of the disease and in time intervention, these may be preventable.

  2. Improvisation skills for clinical work

    DEFF Research Database (Denmark)

    Wigram, Anthony Lewis

    based on a short theme or ‘leit-motif’ will all be included in the workshop activities, using both piano, and other instruments. While interventions utilising improvisational music therapy should never be driven by clinical procedures, applying therapeutic method, and also recognising method...

  3. Ethical dilemmas in clinical genetics.

    OpenAIRE

    Young, I D

    1984-01-01

    This paper discusses the results of a survey of medical and paramedical opinion relating to various difficult ethical issues in clinical genetics. These include the confidentiality of the doctor-patient relationship, prenatal diagnosis and termination, and Huntington's chorea. It is suggested that this method provides a useful means of assessing what is ethically acceptable in contemporary society.

  4. The Future of Clinical Dentistry.

    Science.gov (United States)

    Slavkin, Harold C.

    1998-01-01

    Discussion of the future of clinical dentistry looks at a variety of influences, including historical development factors; demographic trends; the role of the Human Genome Project in the development of scientific knowledge; a paradigm shift in approaches to oral infection and systemic disease; advancing technology; and reforms resulting from these…

  5. Clinical characteristics of infectious spondylodiscitis

    Directory of Open Access Journals (Sweden)

    Knežević Aleksandar

    2009-01-01

    Full Text Available Spondylodiscitis represents an inflammatory process, localized in the vertebrae body and in the intervertebral discs. The goals of this research were to identify subjective complaints, clinical findings, and laboratory characteristics in patients with spondylodiscitis, as well as to establish the importance of magnetic resonance imaging in diagnosing this disease. The data of 40 patients treated at the Clinic for Infectious diseases of the Clinical Center of Vojvodina from 2003 till 2007 were reviewed. Majority of the patients had low back pain (90%. Fever was present in 37.5% of patients (X2= 2,5; p>0,05. Laboratory parameters of inflammation were higher than normal in most of the patients before the treatment. Diagnosis of spondylodiscitis was made using MRI in 97,5% of the patients. Keeping in mind unspecific subjective complaints and clinical findings in patients with spondylodiscitis, a health professional should always suspect spondylodiscitis when back pain occurs, in order to diagnose and treat this severe disease as early as possible. Magnetic resonance imaging is the most advantageous method in diagnosing spondylodiscitis.

  6. Nonverbal Interventions in Clinical Groups.

    Science.gov (United States)

    Shadish, William R., Jr.

    1980-01-01

    A comparison of nonverbal with verbal clinical group interventions suggested that some traditional self-report devices show less differentiation between these two interventions than do measures of group cohesion. A strong, replicable manipulation tested these findings, which were consistent with previous research. (Author/BEF)

  7. Clinical cytogenetics and molecular cytogenetics

    Institute of Scientific and Technical Information of China (English)

    LI Marilyn; PINKEL Daniel

    2006-01-01

    The short report will be focused on helping our students to understand commonly used conventional and cutting edge cytogenetic techniques and their clinical applications, the advances and drawbacks of each technique, and how to pick the right test(s) for a specific patient in order to achieve a proper diagnosis efficiently and economically.

  8. Radon in caves: clinical aspects

    OpenAIRE

    Craven Stephen A.; Smit Berend J.

    2006-01-01

    Historical, experimental and clinical evidence is presented to suggest that radon constitutes a relatively small carcinogenic risk for casual visitors to caves. The risk is dependent on radon levels and the smoking of tobacco. Show cave guides, chronically exposed to radon, may be at increased risk for lung cancer due to the effects of radon, especially if they are smokers of tobacco.

  9. Supervisees' Perception of Clinical Supervision

    Science.gov (United States)

    Willis, Lisa

    2010-01-01

    Supervisors must become aware of the possible conflicts that could arise during clinical supervision. It is important that supervisors communicate their roles and expectations effectively with their supervisees. This paper supports the notion that supervision is a mutual agreement between the supervisee and the supervisor and the roles of…

  10. Randomized clinical trials in HEPATOLOGY

    DEFF Research Database (Denmark)

    Kjaergard, L L; Nikolova, D; Gluud, C

    1999-01-01

    Evidence shows that the quality of randomized clinical trials (RCTs) affects estimates of intervention efficacy, which is significantly exaggerated in low-quality trials. The present study examines the quality of all 235 RCTs published in HEPATOLOGY from the initiation in 1981 through August 1998...

  11. Using Disguised Clinical Case Material

    Science.gov (United States)

    Kantrowitz, Judy L.

    2010-01-01

    When, why, and how clinicians decide to write about clients are ethical concerns. There are risks and potential clinical ramifications as well as responsibilities for how these decisions are made. On the basis of 141 interviews with psychoanalysts who have published in 3 major national and international psychoanalytic journals, the author explores…

  12. Therapeutic Communication and Clinical Instruction.

    Science.gov (United States)

    Karns, Phyllis J.; Schwab, Therese A.

    1982-01-01

    The use of interpersonal skills can greatly enhance the learning process, not only by reducing stress, but also by significantly increasing cognitive growth in students. The authors review these findings and discuss their application to teaching in the clinical area. (CT)

  13. Topics in clinical trial management

    NARCIS (Netherlands)

    B.A. Kirwan (Bridget Anne)

    2004-01-01

    textabstractThe aim of this thesis is to show how clinical trial conduct can be managed while respecting the underlying scientific principles. Chapter 2 describes the main results of PICO (PImobendan in COngestive heart failure), a trial which investigated a positive inotropic agent in patients with

  14. Bias in clinical intervention research

    DEFF Research Database (Denmark)

    Gluud, Lise Lotte

    2006-01-01

    Research on bias in clinical trials may help identify some of the reasons why investigators sometimes reach the wrong conclusions about intervention effects. Several quality components for the assessment of bias control have been suggested, but although they seem intrinsically valid, empirical...

  15. Ongoing clinical trials in AKI.

    Science.gov (United States)

    Faubel, Sarah; Chawla, Lakhmir S; Chertow, Glenn M; Goldstein, Stuart L; Jaber, Bertrand L; Liu, Kathleen D

    2012-05-01

    AKI is an important public health issue. AKI is a common hospital complication associated with increased in-hospital and long-term mortality, extensive morbidity (including prolonged hospital length of stay), and an estimated annual cost of at least $10 billion in the United States. At present, no specific therapy has been developed to prevent AKI, hasten recovery of kidney function, or abrogate the deleterious systemic effects of AKI. However, recent progress includes establishing a consensus definition of AKI and discovery of novel biomarkers that may allow early detection of AKI. Furthermore, significant insights into the pathophysiology of AKI and its deleterious systemic effects have been gleaned from animal studies. Urgently needed are large, definitive randomized clinical trials testing interventions to prevent and/or treat AKI. This review summarizes and analyzes current ongoing clinical trials registered with clinicaltrials.gov that address prevention or management of AKI. The purpose of this review is to provide a resource for people interested in potential prophylactic and therapeutic approaches to patient care and investigators hoping to plan and execute the next round of randomized clinical trials. Finally, this review discusses research needs that are not addressed by the current clinical trials portfolio and suggests key areas for future research in AKI. PMID:22442183

  16. [Clinical pathway "Acute Coronary Syndrome"].

    Science.gov (United States)

    Grimm, W; Maisch, B

    2006-07-01

    The clinical pathway "acute coronary syndrome" of the university hospital Marburg describes the guideline-conform and consented management of patients with ST-segment elevation infarct (STEMI), non-ST-segment elevation infarct (NSTEMI) and Troponin negative unstable angina. A 12-lead ECG recording is made and read in all patients within 10 minutes. All patients with STEMI undergo immediate revascularisation using primary percutanuous catheter intervention (PCI) after administration of basic medical therapy. Primary PCI is also used in all patients with NSTEMI, persistent chest pain, rhythm or hemodynamic instability. Patients with unstable angina, who became free of symptoms after application of basic medication, but who have additional risk factors undergo cardiac catheterisation within 48 hours. Acute myocardial infarction can be ruled out in patients with twofold negative cardiac troponin levels during 6-12 hours. In the absence of further symptoms, these patiens undergo differential diagnostic evaluation of cardiac and extracardiac causes of chest pain. The introduction of this clinical pathway 2 years ago, which was consented before by the hospital board and the clinical directors, has lead to a remarkable improvement in the clinical decision-making at the emergency room of the hospital and reduced the door to intervention time considerably. PMID:16763796

  17. Evidence-based clinical practice

    DEFF Research Database (Denmark)

    Garattini, Silvio; Jakobsen, Janus C; Wetterslev, Jørn;

    2016-01-01

    Using the best quality of clinical research evidence is essential for choosing the right treatment for patients. How to identify the best research evidence is, however, difficult. In this narrative review we summarise these threats and describe how to minimise them. Pertinent literature was consi...

  18. Trichinella infection and clinical disease

    DEFF Research Database (Denmark)

    Clausen, M R; Meyer, C N; Krantz, T;

    1996-01-01

    Trichinellosis is caused by ingestion of insufficiently cooked meat contaminated with infective larvae of Trichinella species. The clinical course is highly variable, ranging from no apparent infection to severe and even fatal disease. We report two illustrative cases of trichinellosis. Returning...

  19. Effect Size in Clinical Phonology

    Science.gov (United States)

    Gierut, Judith A.; Morrisette, Michele L.

    2011-01-01

    The purpose of this article is to motivate the use of effect size (ES) for single-subject research in clinical phonology, with an eye towards meta-analyses of treatment effects for children with phonological disorders. Standard mean difference (SMD) is introduced and illustrated as one ES well suited to the multiple baseline (MBL) design and…

  20. Topics in clinical oncology. 14

    International Nuclear Information System (INIS)

    The symposium proceedings contain 39 papers. All papers were inputted in INIS. The subjects of the papers were the use of computers in radiotherapy planning, and clinical dosimetry, equipment and quality assurance, biological radiation effects and radiation protection problems in radiotherapy. (J.P.)

  1. Clinical Application of Point Diji

    Institute of Scientific and Technical Information of China (English)

    栾继萍

    2004-01-01

    @@ Diji (SP 8) is a cleft point of the Spleen Channel of Foot-Taiyang. Its indications include abdominal pain, diarrhea, edema, dysmenorrhea and certain other symptoms caused by incoordination between the liver and the spleen. Either taking the point alone or together with some other adjunct points in clinical practice, the author has obtained satisfactory curative effects.

  2. Clinical applications of breath testing

    OpenAIRE

    Paschke, Kelly M; Mashir, Alquam; Dweik, Raed A.

    2010-01-01

    Breath testing has the potential to benefit the medical field as a cost-effective, non-invasive diagnostic tool for diseases of the lung and beyond. With growing evidence of clinical worth, standardization of methods, and new sensor and detection technologies the stage is set for breath testing to gain considerable attention and wider application in upcoming years.

  3. CLINICAL STUDY OF ANORECTAL MALFORMATIONS

    OpenAIRE

    Umesh; Sowmya,

    2015-01-01

    BACKGROUND: A norectal malformations are relatively encountered anomalies. Presentations may vary from mild to severe and bowel control is t he main concern. AIM: To study the modes of presentation , types of anomalies , associated anomalies , reliability of clinical signs and radiological investigations in the diagnosis and the prognosis and continence in the post - operative in relation to type of anomaly and associated anomaly (s)...

  4. Teaching Techniques in Clinical Chemistry.

    Science.gov (United States)

    Wilson, Diane

    This master's thesis presents several instructional methods and techniques developed for each of eleven topics or subject areas in clinical chemistry: carbohydrate metabolism, lipid metabolism, diagnostic enzymology, endocrinology, toxicology, quality control, electrolytes, acid base balance, hepatic function, nonprotein nitrogenous compounds, and…

  5. Clinical features in meniscus lesions

    OpenAIRE

    Karli, Mahmut

    2004-01-01

    In some circumstances the diagnosis of meniscus tears can be difficult. In addition to a detalied history and clinical examination standard radiographic, arthrographic and arthroscopic examinations can reduce the errors in diagnosis to less than 5%. General featues are pain, less of function, swelling, giving way. Quadriceps, atrophy and locking. Special test are also very important in the diagnosis of meniscus tears.

  6. HIV/AIDS Clinical Trials Fact Sheet

    Science.gov (United States)

    HIV Prevention HIV/AIDS Clinical Trials (Last updated 9/15/2015; last reviewed 9/15/2015) Key Points HIV/AIDS clinical ... safe and effective in people. What is an HIV/AIDS clinical trial? HIV/AIDS clinical trials help ...

  7. 77 FR 60440 - Clinical Investigator Training Course

    Science.gov (United States)

    2012-10-03

    ... HUMAN SERVICES Food and Drug Administration Clinical Investigator Training Course AGENCY: Food and Drug... are cosponsoring a 3- day training course for clinical investigators on scientific, ethical, and regulatory aspects of clinical trials. This training course is intended to provide clinical...

  8. 78 FR 63988 - Clinical Investigator Training Course

    Science.gov (United States)

    2013-10-25

    ... HUMAN SERVICES Food and Drug Administration Clinical Investigator Training Course AGENCY: Food and Drug... cosponsoring a 3- day training course for clinical investigators on scientific, ethical, and regulatory aspects of clinical trials. This training course is intended to provide clinical investigators with...

  9. MDS clinical diagnostic criteria for Parkinson's disease

    NARCIS (Netherlands)

    Postuma, R.B.; Berg, D; Stern, M.; Poewe, W.; Olanow, C.W.; Oertel, W.; Obeso, J.; Marek, K.; Litvan, I.; Lang, A.E.; Halliday, G.; Goetz, C.G.; Gasser, T.; Dubois, B.; Chan, P.; Bloem, B.R.; Adler, C.H.; Deuschl, G.

    2015-01-01

    This document presents the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's disease (PD). The Movement Disorder Society PD Criteria are intended for use in clinical research but also may be used to guide clinical diagnosis. The benchmark for these criteria is expert clinical di

  10. Common statistical concerns in clinical trials

    OpenAIRE

    Evans, Scott R.

    2010-01-01

    Statistics are an integral part of clinical trials. Elements of statistics span clinical trial design, data monitoring, analyses, and reporting. A solid understanding of statistical concepts by clinicians improves the comprehension and the resulting quality of clinical trials. This manuscript outlines common statistical concerns in clinical trials that are important for clinicians to understand.

  11. Adjustment model of thermoluminescence experimental data; Modelo de ajuste de datos experimentales de termoluminiscencia

    Energy Technology Data Exchange (ETDEWEB)

    Moreno y Moreno, A. [Departamento de Apoyo en Ciencias Aplicadas, Benemerita Universidad Autonoma de Puebla, 4 Sur 104, Centro Historico, 72000 Puebla (Mexico); Moreno B, A. [Facultad de Ciencias Quimicas, UNAM, 04510 Mexico D.F. (Mexico)

    2002-07-01

    This model adjusts the experimental results for thermoluminescence according to the equation: I (T) = I (a{sub i}* exp (-1/b{sub i} * (T-C{sub i})) where: a{sub i}, b{sub i}, c{sub i} are the i-Th peak adjusted to a gaussian curve. The adjustments of the curve can be operated manual or analytically using the macro function and the solver.xla complement installed previously in the computational system. In this work it is shown: 1. The information of experimental data from a LiF curve obtained from the Physics Institute of UNAM which the data adjustment model is operated in the macro type. 2. A LiF curve of four peaks obtained from Harshaw information simulated in Microsoft Excel, discussed in previous works, as a reference not in macro. (Author)

  12. AJUSTE, ESTRUCTURA Y AMBIENTE COMO FACTORES CLAVES EN LA TEORÍA DE CONTINGENCIAS

    Directory of Open Access Journals (Sweden)

    Juan De J. Pinto

    2003-01-01

    Full Text Available Este artículo desarrolla la teoría de contingencias dentro del marco de la evolución de las teorías de la administración, basados en los estudios realizados por Burns y Stalker, Lawrence y Lorsh, Pradip Khandwall quienes hicieron grandes investigaciones en la década de los años 60 y 70 sobre el tema. También se hace un análisis de los aportes hechos por Henry Mintzberg, Van de Ven y Drazin y Stephen Robbins autores contemporáneos que han enriquecido el entendimiento de la teoría de contingencias, determinando la influencia de esta teoría sobre la estrategia, la estructura y el ambiente.

  13. Reseña del libro: Ajuste Cultural de la persona con Discapacidad Intelectual

    Directory of Open Access Journals (Sweden)

    Maira Fernanda Hurtado Abril

    2013-06-01

    Full Text Available El presente trabajo realiza una breve exploración crítica del libro de Verdugo y Gutiérrez (2009, el cual tiene como eje central el análisis de la evolución del término “discapacidad” en los principales sistemas de acción, y la explicación de propuestas de intervención para la adaptabilidad de la persona con discapacidad intelectual. La lectura del libro transcurre de una manera armoniosa, clara y funcional para aquellos interesados en el tema (psicólogos, investigadores, terapeutas, educadores, familiares, buscando así la aplicación conjunta del modelo de una manera práctica y eficaz en la vida cotidiana de estas personas.

  14. Impacto amplificador del ajuste de inventarios ante choques de demanda según especificaciones flexibles

    OpenAIRE

    Barrera, Carlos R.

    2011-01-01

    La presente investigación aproxima cuantitativamente las relaciones dinámicas potencialmente asimétricas entre el crecimiento del PBI, del acervo de inventarios y de tres componentes de la demanda agregada (la demanda interna pública, la demanda interna privada y, en particular, la demanda externa por exportaciones) durante la experiencia peruana de crecimiento basado en el mercado (1993-2010). Para capturar la potencial presencia de asimetrías en el vector de medias condicionales, se propone...

  15. Factores psicoemocionales y ajuste psicológico asociados al cáncer de mama

    OpenAIRE

    Zayas García, Antonio

    2016-01-01

    Falta palabras clave El cáncer es una enfermedad crónica que provoca un gran número de muertes al año (SEOM, 2014), afectando a quienes lo padecen en su esfera tanto física, como psicológica y social. Concretamente el cáncer de mama es el primer tipo de enfermedad neoplásica que se da en las mujeres en este país, presentando unas peculiaridades específicas que hacen que ejerza una influencia, tanto por el impacto de la enfermedad, por los efectos secundarios derivados de los tratamie...

  16. Mercado de servicios de ajustes del sistema eléctrico : propuestas de mejora

    OpenAIRE

    Justo Rojas, Elisa María

    2013-01-01

    En general, el modelo de mercado eléctrico español y la regulación han fomentado la garantía de suministro de energía eléctrica y su calidad, no obstante la mayor parte del diseño del mismo responde al contexto energético que existía en 1998. En los últimos años se han registrado una serie de cambios importantes que han modificado el escenario y el funcionamiento del mercado eléctrico, como son una importante penetración de las energías renovables no gestionables, la incorporac...

  17. Participación de la industria en los servicios de ajuste

    OpenAIRE

    Casals Simó, David

    2014-01-01

    El sistema eléctrico español tiene unas características propias de cualquier sistema eléctrico y otras específicas que le diferencian de otros sistemas eléctricos europeos o extracomunitarios. Una característica común en cualquier sistema eléctrico es la necesidad de igualar la energía eléctrica demandada y la generada en cada momento y en cada punto del sistema, debido a la naturaleza de este tipo de energía, que no puede ser almacenada en grandes cantidades. Pero además hay otros factores p...

  18. Equilibrios de óxido-reducción. Ajuste de reacciones redox. V.

    OpenAIRE

    Milla González, Miguel

    2014-01-01

    En este ejercicio se ajusta la reacción de solubilización de HgS en agua regia que suma el poder oxidante del ácido nítrico y el complejante del cloruro. Encontrar los coeficientes estequiométricos de la reacción es sencillo.

  19. Ajuste macroeconómico y reformas estructurales en Bolivia, 1985-1994

    Directory of Open Access Journals (Sweden)

    Juan Antonio Morales

    1994-12-01

    Full Text Available El propósito principal de este documento es ofrecer un estado de la situación macroeconómica, una revisión del programa de reformas estructurales, que comenzó con la estabilización de agosto de 1985 (con el Decreto Supremo 21060, y un análisis de las perspectivas de crecimiento. Se hace hincapié en las dificultades que Bolivia confronta para reanudar sostenidamente el crecimiento.

  20. AJUSTE A LA CRISIS Y MERCADO LABORAL (PERÚ 2008-2010

    Directory of Open Access Journals (Sweden)

    Norberto E. García

    2011-06-01

    Full Text Available The present paper analyses the adjustment of the Peruvian economy to the external shock caused by the global crisis in 2008-2010, with particular attention to: i the macroeconomic policies adopted to face the external shock; ii the consequences of the adjustment for the labor market; iii the importance of the high rates of economic growth recorded by Peru before the crisis in obtaining a soft adjustment to the external shock; iv the reasons that explained why the Peruvian economy does not suffer a recession and only decelerates growth, which allow us to understand why the adjustment to the external shock does not have a negative effect on the labor market – as a matter of fact there is a reduction of the unemployment rate during the crisis.

  1. Ajuste recursivo con transformaciones invariantes y bootstrapping: El caso de una caminata aleatoria con intercepto

    OpenAIRE

    Eddy Lizarazu Alanez; Jose A. Villasenor Alva

    2010-01-01

    Usamos simulaciones de Monte Carlo para estudiar el desempeno de la prueba de raiz unitaria de Shin-So (DFSS) bajo los enfoques de transformaciones invariantes y el bootstrapping. Si la hipotesis alternativa es un proceso estacionario alrededor de una tendencia lineal, entonces la prueba bootstrap parametrica es la mejor en terminos de la potencia estadistica. Sin embargo, si transformamos las observaciones para construir una prueba invariante, entonces la prueba DFSS es la mejor. Por consigu...

  2. Ajuste de los modelos físicos 802.16 para alta movilidad

    OpenAIRE

    Almagro Carrión, Sergio; Cerdán Cartagena, José Fernando; Luján Fernández, Sergio; Cabrera Lozoya, Andrés

    2009-01-01

    En los útlimos años, la integración de servicios de datos en redes móviles se ha convertido en un objetivo primordial para fabricantes y proveedores de servicios. Dada su robustez y eficiencia, Wimax ha ido ganando protagonismo en dicho mercado, llegando a ser una referencia cuando hablamos de las futuras redes móviles de cuarta generación 4G. Los modelos de simulación para esta tecnología permiten desarrollar nuevas mejoras y conocer su comportamiento. El presente documento se centra en el m...

  3. Diferencias entre universidades privadas y oficiales venezolanas: Algunos ajustes necesarios en el sector privado

    Directory of Open Access Journals (Sweden)

    Luis Fuenmayor Toro

    2003-01-01

    Full Text Available Este trabajo efectúa una caracterización preliminar de la universidad privada venezolana, a medio siglo de sus inicios. Se determinan algunas de sus fallas principales y propone correctivos factibles aprovechando las leyes de educación próximas a ser aprobadas. Los datos demuestran que las universidades privadas, a diferencia de las oficiales, tiene una planta docente mayoritariamente a tiempo convencional, ubicada principalmente en los más bajos escalafones académicos, con estudios de postgrado en una proporción menor que las universidades oficiales y prácticamente sin investigadores. La relación alumno/profesor es el doble de la del sector oficial y los postgrados universitarios que ofrecen son la quinta parte del total y sólo están acreditados el 10%, en contraposición con el 29% acreditado de las instituciones públicas. De estas comparaciones se extrae que la universidad privada está muy limitada para la realización de investigación y para el desarrollo de los postgrados que forman investigadores: maestrías y doctorados. Tiene además limitaciones subsanables en el pregrado, por no disponer de docentes contratados a altas dedicaciones, que dispongan de tiempo dentro de su dedicación para las consultas estudiantiles. Esto se puede resolver a través de un mandato legal que determine que un 33% de los docentes, sin contar autoridades y directivos, deban estar a dedicación exclusiva y repartidos homogéneamente entre todos los programas docentes institucionales. Estos docentes, también por mandato legal, dispondrían de un 30% de su tiempo para hacer investigación en unidades de universidades y otros centros oficiales, a las que serían adscritos formalmente. Ello mejoraría la academia de las instituciones privadas sin costos que hagan imposible estos importantes cambios.

  4. Distribution transformer with automatic voltage adjustment - performance; Transformador de distribucion con ajuste automatico de tension - desempeno

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez Ruiz, Gustavo A.; Delgadillo Bocanegra, Alfonso; Betancourt Ramirez, Enrique [PROLEC-GE, Apodaca, Nuevo Leon (Mexico)]. E-mail: gustavo1.hernandez@ge.com; alfonso.delgadillobocanegra@ge.com; enrique.betancourt@ge.com; Ramirez Arredondo, Juan M. [CINVESTAV-Guadalajara, Zapopan, Jalisco (Mexico)]. E-mail: jramirez@gdl.cinvestav.mx

    2010-11-15

    In the electric power distribution systems, the power quality is strongly linked with the service stability voltage. In the radial kind systems, it is virtually impossible to achieve a flat voltage along the lines, so it is desirable to count with transformers that can adjust automatically the turns ratio. In this work, it is described the development and the performance of a transformer with an integrated electronic tap changer, that allows to change the turns ratio along the standard range of +/-5%, and it was identified the application limits of the technology. [Spanish] En los sistemas de distribucion de energia electrica, la calidad del suministro de energia esta fuertemente ligada con la estabilidad del voltaje de servicio. En sistemas de tipo radial, es virtualmente imposible mantener uniforme la tension a lo largo de las lineas, por lo que se hace deseable contar con transformadores que puedan ajustar automaticamente la relacion de transformacion. En este trabajo, se describe el desarrollo y desempeno de un transformador con switch electronico integrado, que permite variar la relacion de transformacion dentro del rango estandarizado de +/-5%, y se identifican los limites de aplicacion de la tecnologia.

  5. La influencia de las diferencias entre el padre y la madre sobre el ajuste adolescente

    OpenAIRE

    Antonia Jiménez-Iglesias; Carmen Moreno

    2015-01-01

    Este trabajo se centra en analizar cómo influyen en el consumo de sustancias (tabaco, alcohol y cannabis) y el bienestar psicológico adolescente (calidad de vida relacionada con la salud y satisfacción vital) las diferencias entre el padre y la madre en afecto, promoción de la autonomía, revelación, interés y conocimiento. La muestra estuvo compuesta por 10170 chicos y chicas españoles de 13 a 18 años de familias biparentales que participaron en la edición 2006 del estudio Health Behaviour in...

  6. Comparación entre varias poblaciones estándar para el ajuste por edades

    OpenAIRE

    Llorca Díaz Javier; Prieto Salceda Dolores; Dierssen Sotos Trinidad; Delgado-Rodríguez Miguel

    2000-01-01

    FUNDAMENTO: Analizar el efecto que tiene la elección de una población de referencia sobre diferentes indicadores derivados de las tasas de mortalidad ajustadas por edad. MÉTODOS: Las tasas de mortalidad por diferentes causas de muerte en España de 1971 a 1992 son ajustadas empleando cuatro poblaciones de referencia: poblaciones españolas de 1971 y 1992, población estándar europea y población estándar mundial. Los resultados obtenidos con las cuatro poblaciones se comparan empleando tres indic...

  7. La crisis y el ajuste estructural en el sector de la salud

    OpenAIRE

    1985-01-01

    Es preciso distinguir entre la producción de salud y la producción de asistencia sanitaria. La salud es el bien final al que se llega por una combinación de factores y productos intermedios, entre los cuales se cuenta la asistencia sanitaria. Muchas veces las condiciones de vivienda, nutrición, estilo de vida son, en efecto, mucho más importantes para mejorar la salud que la asistencia sanitaria. No mucho más que esta última es, sin embargo, recogido por nuestros limitados sistemas de contabi...

  8. Balancing mechanism status: March 2009; Bilan du mecanisme d'ajustement: mars 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for March 2009. (J.S.)

  9. Balancing mechanism status: September 2009; Bilan du mecanisme d'ajustement: septembre 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for September 2009. (J.S.)

  10. Balancing mechanism status: August 2009; Bilan du mecanisme d'ajustement: aout 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for August 2009. (J.S.)

  11. Balancing mechanism status: April 2009; Bilan du mecanisme d'ajustement: avril 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for April 2009. (J.S.)

  12. Balancing mechanism status: February 2009; Bilan du mecanisme d'ajustement: fevrier 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for February 2009. (J.S.)

  13. Balancing mechanism status: November 2009; Bilan du mecanisme d'ajustement: novembre 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for November 2009. (J.S.)

  14. Balancing mechanism status: July 2009; Bilan du mecanisme d'ajustement: juillet 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for July 2009. (J.S.)

  15. Balancing mechanism status: January 2009; Bilan du mecanisme d'ajustement: janvier 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-03-15

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for January 2009. (J.S.)

  16. Balancing mechanism status: May 2009; Bilan du mecanisme d'ajustement: mai 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for May 2009. (J.S.)

  17. Balancing mechanism status: June 2009; Bilan du mecanisme d'ajustement: juin 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for June 2009. (J.S.)

  18. Balancing mechanism status: October 2009; Bilan du mecanisme d'ajustement: octobre 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for October 2009. (J.S.)

  19. Balancing mechanism status: December 2009; Bilan du mecanisme d'ajustement: decembre 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for December 2009. (J.S.)

  20. Balancing mechanism status: January 2010; Bilan du mecanisme d'ajustement: janvier 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    RTE ensures the real-time balance between production and consumption and deals with congestion on the French electricity system. The Balancing Mechanism assists in the accomplishment of this task. As in many countries, and after extensive dialogue with representatives from the market's various players, RTE proposes a Balancing Mechanism in the form of a permanent and transparent system of calls for tender. The system is open to everyone and provides a real-time reserve of power that can be used for balancing either upward or downward. RTE takes advantage of these offers according to economic precedence, taking into account the system's operating conditions. It pays for them at the offer price. There are two types of offer: - Upward offer: increase in production, decrease in consumption, imports, - Downward offer: decrease in production, increase in consumption, exports. For a Balancing Entity, an offer systematically consists of: a balancing direction (upward/downward), a time period, a price that may vary according to six time slots. RTE publishes each month a Balancing Mechanism Report. which includes the following information: - energy volumes activated to ensure the balance of the system and to resolve congestion; - minimum and maximum prices of offers activated to balance the system; - daily trends calculated according to the predominant value of the overall upward or downward trend; - balancing shares by technology (nuclear, thermal, hydraulic); - characteristics of the five most activated balancing entities; - balances/imbalances accounts and production/consumption overcharge; - congestion curbing costs on the French electricity system; - energy volumes activated to ensure the balance of the system according to contracts between RTE and other Balance Responsible entities (UK, Belgium, Italy, Germany, Switzerland); - reliability of the provisional data supplied by RTE about the balancing trend; - availability of RTE's information services (planning, balancing mechanism, block exchange notification, market indicators). This report presents the above information for January 2010. (J.S.)