Sample records for airbus model a340-200
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76 FR 24351 - Airworthiness Directives; Airbus Model A340-200 and -300 Series Airplanes
2011-05-02
.... Register in the future. Differences Between the AD and the MCAI or Service Information We have reviewed the... described in Airbus A340 Airworthiness Limitations Items Document Ref: AI/SE-M4/95A.0051/97, Issue 10, dated...
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77 FR 37797 - Airworthiness Directives; Airbus Airplanes
2012-06-25
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-200 series airplanes; Airbus Model A330-200 Freighter series airplanes; Airbus Model A330-300 series airplanes; Airbus Model A340-200 series airplanes; and Airbus Model A340-300 series...
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78 FR 32347 - Airworthiness Directives; Airbus Airplanes
2013-05-30
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-200 Freighter, A330-200, A330-300, A340-200, A340- 300, A340-500, and A340-600 series... following service information: Airbus Mandatory Service Bulletin A330-56-3009, Revision 02, including...
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78 FR 21227 - Airworthiness Directives; Airbus Airplanes
2013-04-10
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-200, A330-200 Freighter, A330-300, A340-200, and A340-300 series airplanes; and Model... that, due to similar design, the enhanced MLG bogie pivot pin (Airbus modification 54500) could also be...
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78 FR 47537 - Airworthiness Directives; Airbus Airplanes
2013-08-06
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... all Airbus Model A330-200 and -300 series airplanes, and Model A340-200 and -300 series airplanes. AD... by application of Airbus modification 49590/Service Bulletin (SB) A330-27-3085 [or SB A340-27-4089...
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78 FR 27015 - Airworthiness Directives; Airbus Airplanes
2013-05-09
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-200 and A330-300 series airplanes, and Model A340-200 and A340-300 series airplanes... seal on a solenoid. This AD requires, depending on airplane configuration, modifying three flight...
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78 FR 17071 - Airworthiness Directives; Airbus Airplanes
2013-03-20
... Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for certain Airbus Model A330-200, -300, and -200 Freighter series airplanes; and all Airbus Model A340-200 and -300 series...
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78 FR 60798 - Airworthiness Directives; Airbus Airplanes
2013-10-02
...-0363; Directorate Identifier 2013-NM-031-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... directive (AD) for all Airbus Model A330-200, -300 and -200 Freighter series airplanes, and Model A340-200... information identified in this proposed AD, contact Airbus SAS--Airworthiness Office--EAL, 1 Rond Point...
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78 FR 79292 - Airworthiness Directives; Airbus Airplanes
2013-12-30
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... directive (AD) 2011-24-09 which applied to certain Airbus Model A340-200 and A340-300 series airplanes. AD... AD, contact Airbus SAS-- Airworthiness Office--EAL, 1 Rond Point Maurice Bellonte, 31707 Blagnac...
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78 FR 52405 - Airworthiness Directives; Airbus Airplanes
2013-08-23
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-300, A340-200, and A340-300 series airplanes. This AD was prompted by a determination... Airbus: Amendment 39-17549. Docket No. FAA-2013-0335; Directorate Identifier 2012-NM-187-AD. [[Page 52407...
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77 FR 19071 - Airworthiness Directives; Airbus Airplanes
2012-03-30
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... directive (AD) for certain Airbus Model A330-200, A330-300, A340-500, and A340-600 series airplanes. This AD...: During structural part assembly in Airbus production line, some nuts Part Number (P/N) ASNA2531-4 were...
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78 FR 78694 - Airworthiness Directives; Airbus Airplanes
2013-12-27
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... all Airbus Model A330-200 and -300 series airplanes, and Model A340-200 and -300 series airplanes. AD... certain check valves in the [[Page 78695
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78 FR 31386 - Airworthiness Directives; Airbus Airplanes
2013-05-24
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of...) for all Airbus Model A330-200 and -300 series airplanes; and Model A340-200, -300, -500, and -600 series airplanes. That AD currently requires a one-time detailed inspection of both main landing gear...
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77 FR 76228 - Airworthiness Directives; Airbus Airplanes
2012-12-27
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-300 series airplanes and Model A340-200 and -300 series airplanes. This AD was prompted... operational test. This [EASA] AD also requires reporting operational test results to Airbus. You may obtain...
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78 FR 65187 - Airworthiness Directives; Airbus Airplanes
2013-10-31
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-300 series airplanes and Model A340-200 and -300 series airplanes. This AD was prompted..., and possibly resulting in loss of control of the airplane. DATES: This AD becomes effective December 5...
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78 FR 66861 - Airworthiness Directives; Airbus Airplanes
2013-11-07
...-0834; Directorate Identifier 2012-NM-045-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... 2004-11-08, AD 2004-13-25, AD 2004-18-14, AD 2008-06-07, and AD 2012-04-07 that apply to certain Airbus... Airbus Model A340-200, -300, -500, and -600 series airplanes from the applicability. We are proposing...
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78 FR 46543 - Airworthiness Directives; Airbus Airplanes
2013-08-01
...-0665; Directorate Identifier 2012-NM-082-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A330-300 series airplanes and Model A340-200 and -300 series airplanes. This proposed AD was prompted by reports of corrosion...
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78 FR 78294 - Airworthiness Directives; Airbus Airplanes
2013-12-26
...-1031; Directorate Identifier 2013-NM-155-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... Freighter, and A330-300 series airplanes; and Model A340-200, A340-300, A340-500, and A340-600 series airplanes. This proposed AD was prompted by the failure of the generator control unit-constant speed motor...
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77 FR 19059 - Airworthiness Directives; Airbus Airplanes
2012-03-30
... Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT... all Airbus Model A340-500 and Model -600 series airplanes. This AD requires performing repetitive high... Airbus has issued Mandatory Service Bulletin A340-57-5029, including Appendices 01 and 02, dated February...
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77 FR 7523 - Airworthiness Directives; Airbus Airplanes
2012-02-13
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... directive (AD) for all Airbus Model A340-600 series airplanes. This AD requires modifying the fire.... Relevant Service Information Airbus has issued Mandatory Service Bulletin A340-26-5020, including Appendix...
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77 FR 19065 - Airworthiness Directives; Airbus Airplanes
2012-03-30
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... directive (AD) for all Airbus Model A340-600 series airplanes. This AD requires a detailed inspection for.... Relevant Service Information Airbus has issued All Operators Telex A340-25A5191, dated January 18, 2011...
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78 FR 68347 - Airworthiness Directives; Airbus Airplanes
2013-11-14
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of...-200, A340- 300, A340-500, and A340-600 series airplanes. AD 2009-04-07 required revising the airplane... reference unit (ADIRU) from providing erroneous data to other airplane systems. AD 2011-02-09 required...
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78 FR 64156 - Airworthiness Directives; Airbus Airplanes
2013-10-28
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... directive (AD) for all Airbus Model A340-211 -212, -213, -311, -312, -313, -541, and -642 airplanes. This AD... information identified in this AD, contact Airbus SAS, Airworthiness Office--EAL, 1 Rond Point Maurice...
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Spiller, Olaf
1991-01-01
The provisions applied to the Airbus A340 wing wiring against lightning indirect effects are presented. The construction and installation of the wiring's shielding systems are described, and the analysis and tests performed to determine the effectiveness of the measures taken are discussed. A first evaluation of the results of the theoretical analysis together with the provisional results of tests indicate a sufficient safety margin between required and achieved protection levels.
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78 FR 53640 - Airworthiness Directives; Airbus Airplanes
2013-08-30
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-200 Freighter series airplanes; Model A330-200 and - 300 series airplanes, and Model... of the forward or aft cargo door. To address this condition, Airbus issued four separate Alert...
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77 FR 65799 - Airworthiness Directives; Airbus Airplanes
2012-10-31
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-200 freighter series airplanes, Model A330-200 and - 300 series airplanes, and Model... [Amended] 0 2. The FAA amends Sec. 39.13 by adding the following new AD: 2012-21-20 Airbus: Amendment 39...
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78 FR 37498 - Airworthiness Directives; Airbus Airplanes
2013-06-21
...-0463; Directorate Identifier 2012-NM-165-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A330-200, -200... holidays. For service information identified in this proposed AD, contact Airbus SAS--Airworthiness Office...
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78 FR 25902 - Airworthiness Directives; Airbus Airplanes
2013-05-03
...-0363; Directorate Identifier 2013-NM-031-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A330-200, -300 and -200... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus...
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77 FR 15644 - Airworthiness Directives; Airbus Airplanes
2012-03-16
...-0192; Directorate Identifier 2011-NM-225-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A330-200 and -200... information identified in this proposed AD, contact Airbus SAS--Airworthiness Office--EAL, 1 Rond Point...
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77 FR 65146 - Airworthiness Directives; Airbus Airplanes
2012-10-25
...-1106; Directorate Identifier 2012-NM-084-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A330-200 Freighter, -200..., contact Airbus SAS--Airworthiness Office--EAL, 1 Rond Point Maurice Bellonte, 31707 Blagnac Cedex, France...
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78 FR 26716 - Airworthiness Directives; Airbus Airplanes
2013-05-08
...) of this AD. (1) Within 1,000 flight cycles since the embodiment of Airbus Service Bulletin A330-29-3101 or A340-29-4078 but no earlier than 700 flight cycles after the embodiment of Airbus Service...
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78 FR 71992 - Airworthiness Directives; Airbus Airplanes
2013-12-02
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... certain Airbus Model A318-100 and A319-100 series airplanes, A320-111 airplanes, A320-200 series airplanes... identified in this AD, contact Airbus, Airworthiness Office--EIAS, 1 Rond Point Maurice Bellonte, 31707...
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78 FR 53635 - Airworthiness Directives; Airbus Airplanes
2013-08-30
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for certain Airbus Model A330-200 and... Sec. 39.13 by adding the following new airworthiness directive (AD): 2013-17-03 Airbus: Amendment 39...
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77 FR 66760 - Airworthiness Directives; Airbus Airplanes
2012-11-07
...-1162; Directorate Identifier 2012-NM-002-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A330-200 Freighter, A330... information identified in this proposed AD, contact Airbus SAS--Airworthiness Office--EAL, 1 Rond Point...
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78 FR 29261 - Airworthiness Directives; Airbus Airplanes
2013-05-20
...-0424; Directorate Identifier 2013-NM-014-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A330-200 Freighter, A330... this proposed AD, contact Airbus SAS, Airworthiness Office--EAL, 1 Rond Point Maurice Bellonte, 31707...
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78 FR 29666 - Airworthiness Directives; Airbus Airplanes
2013-05-21
...-0422; Directorate Identifier 2012-NM-097-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A330-200 and -300... information identified in this proposed AD, contact Airbus SAS--Airworthiness Office--EAL, 1 Rond Point...
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77 FR 51729 - Airworthiness Directives; Airbus Airplanes
2012-08-27
...-0810; Directorate Identifier 2011-NM-195-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A330-200, A330-300... identified in this proposed AD, contact Airbus SAS--Airworthiness Office--EAL, 1 Rond Point Maurice Bellonte...
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77 FR 75825 - Airworthiness Directives; Airbus Airplanes
2012-12-26
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-200 and -300 series airplanes. This AD was prompted by a report of a prematurely... [Amended] 0 2. The FAA amends Sec. 39.13 by adding the following new AD: 2012-25-12 Airbus: Amendment 39...
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78 FR 46306 - Airworthiness Directives; Airbus Airplanes
2013-07-31
...-0632; Directorate Identifier 2013-NM-045-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A330-200 and -300 series... identified in this proposed AD, contact Airbus SAS, Airworthiness Office--EAL, 1 Rond Point Maurice Bellonte...
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78 FR 28159 - Airworthiness Directives; Airbus Airplanes
2013-05-14
...-0418; Directorate Identifier 2012-NM-200-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A300 series airplanes; Model A300 B4-600, B4-600R, and F4-600R series airplanes, and Model A300 C4-605R Variant F airplanes...
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77 FR 39186 - Airworthiness Directives; Airbus Airplanes
2012-07-02
...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A318, A319, A320, and... identified in this proposed AD, contact Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte... 200, Suite 400, College Park, Georgia 30337; telephone 678-228-8153; fax 404-599-0041; email techpubs...
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75 FR 26881 - Airworthiness Directives; Airbus Model A340-200 and A340-300 Series Airplanes
2010-05-13
...;Prices of new books are listed in the first FEDERAL REGISTER issue of each #0;week. #0; #0; #0; #0;#0... the incorporation by reference of a certain publication listed in this AD. We must receive comments on... the overall regulatory, economic, environmental, and energy aspects of this AD. We will consider all...
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78 FR 41280 - Airworthiness Directives; Airbus Airplanes
2013-07-10
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A319-112, -113, and -132 airplanes; Model A320-211, -212, -214, -231, and -232 airplanes... A319 aeroplane on which Airbus modification (mod.) 22058 had been embodied in production. Airbus mod...
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2010-02-23
... Airworthiness Directives; Airbus Model A310-203, -221, -222 Airplanes; and Model A300 F4-605R and -622R...-222 airplanes, all serial numbers. (2) Airbus Model A300 F4-605R and A300 F4-622R airplanes, all...
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77 FR 42952 - Airworthiness Directives; Airbus Airplanes
2012-07-23
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318-112 and -121 airplanes; Model A319-111, -112, -115, - 132, and -133 airplanes; Model... MCAI states: During structural part assembly in Airbus production line, some nuts Part Number (P/N...
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77 FR 64701 - Airworthiness Directives; Airbus Airplanes
2012-10-23
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A300 series airplanes; Model A310 series airplanes; and Model A300 B4-600, B4-600R, and F4... that the AD be effective after Airbus completes certifying the improved design for the fuel pump half...
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78 FR 9787 - Airworthiness Directives; Airbus Airplanes
2013-02-12
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A300 B4-600, B4-600R, and F4-600R series airplanes, and Model A300 C4-605R Variant F airplanes (collectively called Model A300- 600 series airplanes); and Airbus [[Page 9788
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78 FR 70003 - Airworthiness Directives; Airbus Airplanes
2013-11-22
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A300 series airplanes; Airbus Model A300 B4-600, B4-600R, and F4-600R series airplanes, and Model...
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2013-12-17
...-0899; Notice No. 25-13-15-SC] Special Conditions: Airbus, Model A350-900 Series Airplane; Control... of proposed special conditions. SUMMARY: This action proposes special conditions for the Airbus Model..., data, or views. The most helpful comments reference a specific portion of the proposed special...
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75 FR 39863 - Airworthiness Directives; Airbus Model A310 Series Airplanes
2010-07-13
... condition as: Analysis performed in the frame of the Extended Service Goal has led Airbus to modify the... performed in the frame of the Extended Service Goal has led Airbus to modify the inspection programme...) states: Analysis performed in the frame of the Extended Service Goal has led Airbus to modify the...
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77 FR 73343 - Airworthiness Directives; Airbus Airplanes
2012-12-10
...-1224; Directorate Identifier 2012-NM-112-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A300 B4-600, B4-600R, and... holidays. For Airbus service information identified in this proposed AD, contact Airbus SAS-EAW...
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78 FR 52414 - Airworthiness Directives; Airbus Airplanes
2013-08-23
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A320-214, -232 and -233 airplanes; and Model A321-211, - 213, and -231 airplanes. This AD... Service Information Airbus requested that we revise the NPRM (77 FR 63270, October 16, 2012) to reflect...
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77 FR 24137 - Airworthiness Directives; Airbus Airplanes
2012-04-23
... Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule... Register. That AD applies to all Airbus Model A300 B4-600, B4-600R, and F4-600R series airplanes, Model... Airbus Model A300 B4-600, B4- 600R, and F4-600R series airplanes, Model A300 C4-605R Variant F airplanes...
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78 FR 69594 - Airworthiness Directives; Airbus Airplanes
2013-11-20
...-0972; Directorate Identifier 2002-NM-009-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... airworthiness directive (AD) for all Airbus Model A330 series airplanes. The NPRM would have required... rulemaking (NPRM) for a new AD for all Airbus Model A330 series airplanes. The NPRM, FAA Docket No. FAA-2013...
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77 FR 40485 - Airworthiness Directives; Airbus Airplanes
2012-07-10
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... (AD) for all Airbus Model A300 series airplanes; all Model A300 B4-600, B4-600R, and F4-600R series... new AD: 2012-13-06 Airbus: Amendment 39-17108. Docket No. FAA-2012-0040; Directorate Identifier 2011...
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78 FR 9581 - Airworthiness Directives; Airbus Airplanes
2013-02-11
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A300 B4-600, B4-600R, and F4-600R series airplanes, and Model A300 C4-605R Variant F...-03-11 Airbus: Amendment 39-17346. Docket No. FAA-2012-1002; Directorate Identifier 2012-NM-052-AD. (a...
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77 FR 16430 - Airworthiness Directives; Airbus Airplanes
2012-03-21
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A300 B4-600, B4-600R, and F4-600R series airplanes, and Model C4-605R Variant F airplanes.../N A5231007000600. This [EASA] AD has been corrected to make clear that the use of Airbus SB A310...
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78 FR 15874 - Airworthiness Directives; Airbus Airplanes
2013-03-13
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A300 B4-600, B4-600R, and F4-600R series airplanes, and Model A300 C4-605R Variant F... ground threat avoidance, an Airbus A310 aeroplane experienced an uncommanded slide back of the co-pilot...
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77 FR 75833 - Airworthiness Directives; Airbus Airplanes
2012-12-26
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of...) for certain Airbus Model A300 B4-2C, B4-103, and B4-203 airplanes; and Model A300 B4-601, B4-603, B4... accordance with Airbus SB A300-57-6053 (Mod. 10453). Therefore and pending completion of the full analysis...
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77 FR 51717 - Airworthiness Directives; Airbus Airplanes
2012-08-27
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... applies to certain Airbus Model A300 B4-2C, B4-103, and B4- 203 airplanes; and Model A300 B4-601, B4-603... information identified in this proposed AD, contact Airbus SAS--EAW (Airworthiness Office), 1 Rond Point...
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76 FR 13075 - Airworthiness Directives; Airbus Model A330-243F Airplanes
2011-03-10
... Airworthiness Directives; Airbus Model A330-243F Airplanes AGENCY: Federal Aviation Administration (FAA... recent in-service event the flight crew of a Trent 700 powered A330 aircraft [[Page 13076
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77 FR 26937 - Airworthiness Directives; Airbus Airplanes
2012-05-08
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of...) for certain Airbus Model A300 B2-1C, B2K-3C, B2-203, B4-2C, B4-103, and B4-203 airplanes; and Model... Airbus Service Bulletins (SB) A300-57-0235 and A300-57-6088 * * *. Subsequently, new cases of cracks were...
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78 FR 51058 - Airworthiness Directives; Airbus Airplanes
2013-08-20
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... certain Airbus Model A319 and A320 series airplanes. AD 2004-13-06 required repetitive detailed... and to allow extension of the interval between two consecutive inspections, Airbus validated an Eddy...
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77 FR 73340 - Airworthiness Directives; Airbus Airplanes
2012-12-10
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... earlier proposed airworthiness directive (AD) for all Airbus Model A318, A319, A320, and A321 series..., contact Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte, 31707 Blagnac Cedex, France...
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78 FR 21230 - Airworthiness Directives; Airbus Airplanes
2013-04-10
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318, A319, and A320 series airplanes. This AD was prompted by fuel system reviews conducted..., Airbus developed a modification which includes installing Ground Fault Interrupters (GFI) into the centre...
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78 FR 23105 - Airworthiness Directives; Airbus Airplanes
2013-04-18
... Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for certain Airbus Model... Agency] has received a report via Airbus and Messier-Bugatti-Dowty Ltd, from a Maintenance repair...
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77 FR 19067 - Airworthiness Directives; Airbus Airplanes
2012-03-30
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... directive (AD) for certain Airbus Model A321-131, -211, -212, and -231 airplanes. This AD requires a.... Relevant Service Information Airbus has issued Mandatory Service Bulletin A320-57-1120, Revision 01...
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77 FR 12989 - Airworthiness Directives; Airbus Airplanes
2012-03-05
... Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for certain Airbus Model.... Airbus carried out an investigation, demonstrating that the life limit of retraction brackets must be...
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78 FR 54377 - Airworthiness Directives; Airbus Airplanes
2013-09-04
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318, A319, A320, and A321 series airplanes. This AD was prompted by reports that certain... accordance with the Accomplishment Instructions of Airbus Service Bulletin A320-27- 1214, including Appendix...
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78 FR 64162 - Airworthiness Directives; Airbus Airplanes
2013-10-28
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318, A319, A320, and A321 series airplanes. This AD was prompted by a determination that...., Washington, DC. For service information identified in this AD, contact Airbus, Airworthiness Office--EIAS, 1...
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78 FR 68352 - Airworthiness Directives; Airbus Airplanes
2013-11-14
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A330-223F, -223, -321, -322, and -323 airplanes. This AD was prompted by fatigue load... this AD, contact Airbus SAS, Airworthiness Office--EAL, 1 Rond Point Maurice Bellonte, 31707 Blagnac...
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78 FR 18925 - Airworthiness Directives; Airbus Airplanes
2013-03-28
...-0212; Directorate Identifier 2012-NM-116-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A330-223F, -223, -321...., Monday through Friday, except Federal holidays. For Airbus service information identified in this...
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77 FR 65808 - Airworthiness Directives; Airbus Airplanes
2012-10-31
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A320-214 and -232 airplanes. This AD was prompted by reports that medium-head fasteners were... installation of upper panels on Frame 35 in Airbus A320 final assembly line. Investigations revealed that...
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77 FR 26996 - Airworthiness Directives; Airbus Airplanes
2012-05-08
...-0427; Directorate Identifier 2011-NM-202-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A320-214 and-232... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus...
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78 FR 60667 - Airworthiness Directives; Airbus Airplanes
2013-10-02
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... all Airbus Model A318, A319, A320, and A321 series airplanes. AD 2012- 26-51 required revising the...''), to correct an unsafe condition for the specified products. The MCAI states: Recently, an Airbus A330...
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78 FR 39190 - Airworthiness Directives; Airbus Airplanes
2013-07-01
...-0543; Directorate Identifier 2012-NM-202-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A318, A319, A320, and... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus...
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76 FR 72350 - Airworthiness Directives; Airbus Airplanes
2011-11-23
...-1253; Directorate Identifier 2011-NM-079-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A319, A320, and A321... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus...
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78 FR 32345 - Airworthiness Directives; Airbus Airplanes
2013-05-30
... Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Airbus Model A300... FedEx requested that copies of Airbus Service Bulletin A300-53- 6170, dated May 16, 2011, be provided...
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78 FR 14029 - Airworthiness Directives; Airbus Airplanes
2013-03-04
...-0096; Directorate Identifier 2012-NM-143-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A318-112, A319-111... Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte, 31707 Blagnac Cedex, France; telephone...
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77 FR 66762 - Airworthiness Directives; Airbus Airplanes
2012-11-07
...-1159; Directorate Identifier 2012-NM-028-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A310-203, -204, -222... information identified in this proposed AD, contact Airbus SAS--EAW (Airworthiness Office), 1 Rond Point...
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78 FR 79333 - Airworthiness Directives; Airbus Airplanes
2013-12-30
...-1066; Directorate Identifier 2013-NM-021-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to supersede airworthiness directive (AD) 2000-12- 12, for certain Airbus Model A300, A300... this proposed AD, contact Airbus SAS, Airworthiness Office--EAW, 1 Rond Point Maurice Bellonte, 31707...
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78 FR 14647 - Airworthiness Directives; Airbus Airplanes
2013-03-07
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... (AD) for certain Airbus Model A310-204, -222, -304, -322, and -324 airplanes. This AD was prompted by... the Airbus A310 Airworthiness Limitation Section (ALS) Part 1 and bolts must be replaced at or before...
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77 FR 16492 - Airworthiness Directives; Airbus Airplanes
2012-03-21
...-0291; Directorate Identifier 2011-NM-168-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A318-112, and -121... identified in this proposed AD, contact Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte...
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78 FR 19085 - Airworthiness Directives; Airbus Airplanes
2013-03-29
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318, A319, A320, and A321 series airplanes. This AD was prompted by reports of oil residue... (MCAI) states: During Airbus Final Assembly Line flight tests, AoA [angle of attack] data from two...
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77 FR 60325 - Airworthiness Directives; Airbus Airplanes
2012-10-03
...-1253; Directorate Identifier 2011-NM-079-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... directive (AD) that would supersede an existing AD for certain Airbus Model A318, A319, A320, and A321... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus...
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77 FR 64765 - Airworthiness Directives; Airbus Airplanes
2012-10-23
...-1105; Directorate Identifier 2012-NM-137-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A318, A319, and A320... identified in this proposed AD, contact Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte...
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77 FR 11793 - Airworthiness Directives; Airbus Airplanes
2012-02-28
...-0185; Directorate Identifier 2011-NM-001-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A300 B4-103, B4-203... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus...
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78 FR 71996 - Airworthiness Directives; Airbus Airplanes
2013-12-02
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318-112, A319-111, A319-112, A319-115, A319-132, and A319-133 airplanes. This AD was... developing this AD. We have considered the comments received. Request To Refer to Revised EASA AD Airbus...
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77 FR 57003 - Airworthiness Directives; Airbus Airplanes
2012-09-17
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318, A319, and A320 series airplanes. This AD was prompted by a report of a torn out.... The FAA amends Sec. 39.13 by adding the following new AD: 2012-18-12 Airbus: Amendment 39-17189...
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77 FR 26998 - Airworthiness Directives; Airbus Airplanes
2012-05-08
...-0428; Directorate Identifier 2011-NM-078-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A330-243, -243F, -342..., between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. For Airbus service information...
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76 FR 69168 - Airworthiness Directives; Airbus Airplanes
2011-11-08
...-1225; Directorate Identifier 2010-NM-269-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A300 B4-2C, B4-103..., contact Airbus SAS-EAW (Airworthiness Office), 1 Rond Point Maurice Bellonte, 31707 Blagnac Cedex, France...
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76 FR 62673 - Airworthiness Directives; Airbus Airplanes
2011-10-11
...-1066; Directorate Identifier 2011-NM-050-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD), for certain Airbus Model A300 B2-1C, B2K-3C... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus...
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76 FR 68671 - Airworthiness Directives; Airbus Airplanes
2011-11-07
...-1170; Directorate Identifier 2010-NM-264-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for all Airbus Model A300 B4-600, B4-600R, and... Friday, except Federal holidays. For Airbus service information identified in this proposed AD, contact...
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78 FR 78705 - Airworthiness Directives; Airbus Airplanes
2013-12-27
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... all Airbus Model A318 series airplanes, Model A319 series airplanes, Model A320 series airplanes, and Model A321 series airplanes. AD 2010- 24-07 required repetitive inspections of the 80VU rack lower...
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75 FR 57880 - Airworthiness Directives; Airbus Model A310 Series Airplanes
2010-09-23
... docket. Relevant Service Information Airbus has issued Mandatory Service Bulletin A310-27-2099, Revision... Service Bulletin A310-27-2099, dated February 17, 2006; or Airbus Mandatory Service Bulletin A310-27-2099...- 2099, Revision 01, dated March 21, 2008. Note 1: For the purposes of this AD, a detailed inspection is...
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77 FR 59149 - Airworthiness Directives; Airbus Airplanes
2012-09-26
...-1002; Directorate Identifier 2012-NM-052-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to adopt a new airworthiness directive (AD) for certain Airbus Model A300 B4-600, B4-600R...: Airbus: Docket No. FAA-2012-1002; Directorate Identifier 2012-NM- 052-AD. (a) Comments Due Date We must...
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78 FR 37437 - Airworthiness Directives; Airbus Airplanes
2013-06-21
... Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT... Airbus Model A318, A319, A320, and A321 series airplanes. That AD currently requires one-time and... affected by AOT A320-55-1039 and Airbus SB A320-55-1035, A320-55- 1036 and A320-55-1037 which were not...
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77 FR 66772 - Airworthiness Directives; Airbus Airplanes
2012-11-07
...-1158; Directorate Identifier 2011-NM-232-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to supersede an existing airworthiness directive (AD) that applies to all Airbus Model... that AD, Airbus has revised certain ALI documents, which require more restrictive maintenance...
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77 FR 37829 - Airworthiness Directives; Airbus Airplanes
2012-06-25
...-0671; Directorate Identifier 2011-NM-096-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to supersede an existing airworthiness directive (AD) that applies to certain Airbus Model... this proposed AD, contact Airbus SAS--Airworthiness Office--EAL, 1 Rond Point Maurice Bellonte, 31707...
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78 FR 9341 - Airworthiness Directives; Airbus Airplanes
2013-02-08
...-0088; Directorate Identifier 2011-NM-233-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to supersede an existing airworthiness directive (AD) that applies to all Airbus Model... this proposed AD, contact Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte, 31707...
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78 FR 70207 - Airworthiness Directives; Airbus Airplanes
2013-11-25
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A300 series airplanes; Model A300 B4-600, B4-600R, and F4- 600R series airplanes; and Model A300 C4-605R Variant F airplanes (collectively called Model A300-600 series airplanes). This AD was...
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2011-01-13
... the rudder. The loss of the rudder leads to degradation of the handling qualities and reduces the..., may degrade the structural integrity of the rudder. The loss of the rudder leads to degradation of the... carbon fiber reinforced plastic rudders having part numbers and serial numbers listed in Table 1 of this...
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2011-04-21
... structural integrity of the rudder. The loss of the rudder leads to degradation of the handling qualities and... degradation of the handling qualities and reduces the controllability of the aeroplane. EASA AD 2009-0156... manufacturer serial numbers; certificated in any category; equipped with carbon fiber reinforced plastic...
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76 FR 18038 - Airworthiness Directives; Airbus Model A340-200 and -300 Series Airplanes
2011-04-01
... as being a combined failure of the thrust reverser pivoting door primary lock and actuator..., this AD requires installation of a new modified primary lock and a new modified actuator on the 10... requirements.'' Under that section, Congress charges the FAA with promoting safe flight of civil aircraft in...
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2010-12-30
...-CN, dated September 20, 2010, to cancel EASA AD 2010-0083, dated May 3, 2010, for the specified products. EASA AD 2010-0083-CN states: It has been assessed that multiple NRV [non return valve] failures... not have a significant economic impact, positive or negative, on a substantial number of small...
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2011-06-10
... products listed above. Since we issued AD 2009-18-19, EASA issued Airworthiness Directive 2010-0083-CN.... EASA AD 2010-0083-CN states: It has been assessed that multiple NRV [non-return valve] failures in..., positive or negative, on a substantial number of small entities under the criteria of the Regulatory...
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78 FR 7261 - Airworthiness Directives; Airbus Airplanes
2013-02-01
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A310-203 airplanes. This AD was prompted by a report of an analysis that demonstrated a...-116, Transport Airplane Directorate, FAA, 1601 Lind Avenue SW., Renton, WA 98057-3356; telephone (425...
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78 FR 49915 - Airworthiness Directives; Airbus Airplanes
2013-08-16
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of..., for certain Airbus Model A310 series airplanes. AD 2004-15-07 required repetitive inspections for..., International Branch, ANM-116, Transport Airplane Directorate, FAA, 1601 Lind Avenue SW., Renton, WA 98057-3356...
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78 FR 65173 - Airworthiness Directives; Airbus Airplanes
2013-10-31
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus Model A318, A319, A320, and A321 series airplanes. This AD was prompted by a determination that... Airplane Directorate, 1601 Lind Avenue SW., Renton, WA. For information on the availability of this...
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2011-05-11
... Airworthiness Directives; Airbus Model A300 B4-600, B4-600R, and F4-600R Series Airplanes, and Model C4-605R... applies to all Airbus Model A300 B4-601, B4-603, B4- 620, B4-622, B4-605R, B4-622R, F4-605R, F4-622R, and...
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2011-09-23
... Airworthiness Directives; Airbus Model A300 B4-600, B4-600R, and F4-600R Series Airplanes, and Model C4-605R... to Airbus Model A300 B4-601, B4-603, B4-620, B4-622, B4-605R, B4-622R, F4-605R, F4-622R, and C4-605R...
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77 FR 49386 - Airworthiness Directives; Airbus Airplanes
2012-08-16
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Airbus..., except Federal holidays. For Airbus service information identified in this proposed AD, contact Airbus...
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78 FR 76572 - Airworthiness Directives; Airbus Airplanes
2013-12-18
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Airbus..., except Federal holidays. For Airbus service information identified in this proposed AD, contact Airbus...
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77 FR 65812 - Airworthiness Directives; Airbus Airplanes
2012-10-31
... airplanes; and Model A340-200 and -300 series airplanes. This AD was prompted by reports of ram air turbine... before delivery from production, an A330 aeroplane experienced a RAT [ram air turbine] pump failure, as a result of which, the green hydraulic system could not be fully pressurized. Investigations concluded that...
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2013-12-17
... the comment (or signing the comment for an association, business, labor union, etc.). DOT's complete... design feature: The digital systems architecture for the Airbus Model A350-900 series airplanes is composed of several connected networks. This proposed network architecture is used for a diverse set of...
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78 FR 1723 - Airworthiness Directives; Airbus Airplanes
2013-01-09
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule; request for comments. SUMMARY: We are adopting a new airworthiness directive (AD) for all Airbus... Friday, except Federal holidays. For service information identified in this AD, contact Airbus...
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75 FR 35 - Special Conditions: Airbus Model A318-112 Airplane (S/N 3886); Certification of a Cooktop
2010-01-04
... Recommended Practice 85, Rev. E, article titled, ``Air Conditioning Systems for Subsonic Airplanes,'' August 1...; Special Conditions No. 25-398-SC] Special Conditions: Airbus Model A318-112 Airplane (S/N 3886... airplane, as modified by Bizjet, a Lufthansa Technik Company, will have a novel or unusual design feature...
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76 FR 78524 - Airworthiness Directives; Airbus Airplanes
2011-12-19
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Airbus... an aeroplane from the Airbus production line, a fault message was triggered on FDU1 [fire detection...
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77 FR 15636 - Airworthiness Directives; Airbus Airplanes
2012-03-16
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Airbus... identified in this proposed AD, contact Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice Bellonte...
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2010-05-21
... Airworthiness Directives; Airbus Model A300 Series Airplanes; Model A300 B4-600, B4-600R, F4-600R Series..., B4-622, B4- 605R, B4-622R, F4-605R, F4-622R, and C4-605R Variant F airplanes; and Model A310-203...
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78 FR 59295 - Airworthiness Directives; Airbus Airplanes
2013-09-26
...-0829; Directorate Identifier 2013-NM-085-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to supersede airworthiness directive (AD) 2010-23- 12, which applies to certain Airbus... through Friday, except Federal holidays. For Airbus service information identified in this proposed AD...
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78 FR 51117 - Airworthiness Directives; Airbus Airplanes
2013-08-20
...-0698; Directorate Identifier 2012-NM-136-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes...: We propose to supersede airworthiness directive (AD) 2006-06- 14, that applies to certain Airbus... information identified in this proposed AD, contact Airbus, Airworthiness Office--EAS, 1 Rond Point Maurice...
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78 FR 64159 - Airworthiness Directives; Airbus Airplanes
2013-10-28
... Airworthiness Directives; Airbus Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... Airbus SAS-- EAW (Airworthiness Office), 1 Rond Point Maurice Bellonte, 31707 Blagnac Cedex, France; telephone +33 5 61 93 36 96; fax +33 5 61 93 44 51; email [email protected]airbus.com ; Internet http...
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77 FR 66764 - Airworthiness Directives; Airbus Airplanes
2012-11-07
...-1160; Directorate Identifier 2012-NM-096-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... Friday, except Federal holidays. For service information identified in this proposed AD, contact Airbus... +33 5 61 93 36 96; fax +33 5 61 93 45 80; email [email protected]airbus.com ; Internet http...
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Computer aided design around the A300 Airbus
Audy, J J
1982-01-01
More than thirteen years after the launching of the first AIRBUS development a survey of CAD/CAM introduction and operation at AEROSPATIALE, Aircraft Division was conducted. The results of this survey are described. Initially, a short description of AEROSPATIALE Aircraft Division is given and the state of CAD/CAM expertise in the factory before the Airbus project is outlined. Next, the author describes the implementation of CAE in the structural, aerodynamic and electrical fields in response to the growing success of the various Airbus programs and in front of an everyday tougher competition. After a description of the present situation and a first estimate of CAE benefits, special attention is devoted to the difficulties encountered with both hardware and software used in the systems involved. To conclude the author defines the respective roles of the system buyer and vendor in the CAD/CAM field.
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78 FR 28152 - Airworthiness Directives; Airbus Airplanes
2013-05-14
...-0416; Directorate Identifier 2012-NM-144-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... A318-111 and -112 airplanes, Model A319 series airplanes, Model A320 series airplanes, and Model A321 series airplanes. The existing AD currently requires repetitive inspections of the 80VU rack lower...
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Protection against wing icing for Airbus A300 and A310
Woelfer, G.
1981-01-01
To improve economy of operation, it is now planned to modify the anti-icing system used on the A300 Airbus wing. Thus, for the A310 Airbus, the deicing system will be applied to only half the wing length. Other essential modifications are a substantial simplification of the warm-air system and discontinuation of the use of a double wall in slats.
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2011-06-22
... pieces unit with 3 welds (old design) as pictured in Appendix 1 of this [EASA] AD. The welding process of... pre-modification 02447.. Blue and Green. A300 airplanes post-modification 02447. Blue. A300-600 airplanes Blue. A310 airplanes Green. Table 2--Applicable service information Airbus mandatory service...
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75 FR 50856 - Airworthiness Directives; Airbus Model A380-800 Series Airplanes
2010-08-18
... it in the AD docket. List of Subjects in 14 CFR Part 39 Air transportation, Aircraft, Aviation safety... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2010... been found on the Droop Nose (DN) 1 master sidestay bracket on the inboard leading edge of an Airbus...
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2011-08-05
... Airworthiness Directives; Airbus Model A300 B4-600, A300 B4-600R, and A300 F4-600R Series Airplanes, and Model..., B4-622R, F4-605R, F4-622R, and C4-605R Variant F airplanes; and Model A310-203, -204, -221, -222...
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2011-05-04
... Airworthiness Directives; Airbus Model A300 B4-600, A300 B4-600R, and A300 F4-600R Series Airplanes, and Model...-605R, B4-622R, F4-605R, F4-622R, and C4-605R Variant F airplanes; and Model A310-203, -204, -221, -222...
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78 FR 78285 - Airworthiness Directives; Airbus Airplanes
2013-12-26
...-1064; Directorate Identifier 2012-NM-101-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... A300 B4-605R and B4-622R airplanes; Model A300 F4-605R airplanes; and Model A300 C4-605R Variant F airplanes. AD 2005-23-08 required repetitive inspections to detect cracks of certain attachment holes...
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2010-12-10
... Airworthiness Directives; Airbus Model A300 B4-600, B4-600R, and F4-600R Series Airplanes, and Model C4-605R... airplanes; Model A300 B4-605R and B4-622R airplanes; Model A300 F4-605R and F4-622R airplanes; Model A300 C4...
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78 FR 40069 - Airworthiness Directives; Airbus Airplanes
2013-07-03
...-0539; Directorate Identifier 2012-NM-145-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... B4-600 and Model A300 B4-600R series airplanes. That AD currently requires repetitive inspections to... information at the FAA, Transport Airplane Directorate, 1601 Lind Avenue SW., Renton, WA. For information on...
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77 FR 6023 - Airworthiness Directives; Airbus Airplanes
2012-02-07
...-0038; Directorate Identifier 2011-NM-209-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... airplanes and Model A310-203, -204, - 221, and -222 airplanes. This proposed AD was prompted by a report of... explosion and consequent loss of the airplane. DATES: We must receive comments on this proposed AD by March...
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2011-07-18
... Airworthiness Directives; Airbus Model A300 B4-600, B4-600R, and F4-600R Series Airplanes, and Model A300 C4... A300 B4-605R and B4-622R airplanes, Model A300 F4-605R and F4-622R airplanes, and Model A300 C4- [[Page...
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2011-07-06
... Airworthiness Directives; Airbus Model A300 B4-600, B4-600R, and F4-600R Series Airplanes, and Model C4-605R... B4-605R and B4-622R airplanes; Model A300 F4-605R and F4-622R airplanes; Model A300 C4-605R Variant F...
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Airbus windshear warning and guidance system
Bonafe, J. L.
1990-01-01
From its first designed airplane, Airbus considered mandatory a help in the crew's decision-making process to initiate an escape maneuver and help to successfully realize it. All the Airbus airplanes designed since 1975 included an alpha-floor function and a speed reference control law imbedded in the speed reference system (SRS) box for A 300 and FAC and FCC for A 310, A300/600 and the A 320. Alpha-Floor function takes into account the airplane energy situation considering angle of attack and observed longitudinal situation in order to apply immediately the full power without any pilot action. Speed reference managers control airspeed and/or ground speed in order to survive a maximum in shear situation. In order to comply with the new FAA regulation: Aerospatiale and Airbus developed more efficient systems. A comparison between 1975 and a newly developed system is given. It is explained how the new system improves the situation.
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Zur aktuellen deutschen Förderung der Airbus-Industrie
Maennig, Wolfgang; Hölzer, Katharina
1999-01-01
Das Projekt „Airbus" war lange Zeit aufgrund der hohen Subventionierung umstritten. Die Kritik hat sich gelegt, weil inzwischen meist angenommen wird, daß die Airbus-Industrie keine substantielle staatliche Förderung mehr erfährt. Wie umfangreich ist die staatliche Förderung aber tatsächlich?
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2011-01-05
... Airworthiness Directives; Airbus Model A300 B4-600, B4-600R, and F4-600R Series Airplanes, and Model C4-605R...-622, B4-605R, B4-622R, F4-605R, F4-622R, and C4-605R Variant F airplanes, certificated in any category...
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Concentrations of selected contaminants in cabin air of airbus aircrafts.
Dechow, M; Sohn, H; Steinhanses, J
1997-07-01
The concentrations of selected air quality parameters in aircraft cabins were investigated including particle numbers in cabin air compared to fresh air and recirculation air, the microbiological contamination and the concentration of volatile organic compounds (VOC). The Airbus types A310 of Swissair and A340 of Lufthansa were used for measurements. The particles were found to be mainly emitted by the passengers, especially by smokers. Depending on recirculation filter efficiency the recirculation air contained a lower or equal amount of particles compared to the fresh air, whereas the amount of bacteria exceeded reported concentrations within other indoor spaces. The detected species were mainly non-pathogenic, with droplet infection over short distances identified as the only health risk. The concentration of volatile organic compounds (VOC) were well below threshold values. Ethanol was identified as the compound with the highest amount in cabin air. Further organics were emitted by the passengers--as metabolic products or by smoking--and on ground as engine exhaust (bad airport air quality). Cleaning agents may be the source of further compounds.
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78 FR 76248 - Special Conditions: Airbus, Model A350-900 Series Airplane; Side Stick Controller
2013-12-17
... one hand. The applicable airworthiness regulations do not contain adequate or appropriate safety standards for this design feature. These proposed special conditions contain the additional safety standards...-hand operation by wrist and not by arms. Discussion Special conditions for Airbus side stick...
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2011-05-02
... specified products. The MCAI states: Airbus, in the frame of the Extended Service Goal (ESG) exercise, has...) states: Airbus, in the frame of the Extended Service Goal (ESG) exercise, has demonstrated by post... aviation product. The MCAI describes the unsafe condition as: Airbus, in the frame of the Extended Service...
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2011-05-13
... Jersey Avenue, SE., Washington, DC. FOR FURTHER INFORMATION CONTACT: Dan Rodina, Aerospace Engineer... the required inspections that will ensure the continued damage tolerance of the affected structure... corroded structure detected during any inspection done in accordance with the Airbus A300 Airworthiness...
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The First European Parabolic Flight Campaign with the Airbus A310 ZERO-G
Pletser, Vladimir; Rouquette, Sebastien; Friedrich, Ulrike; Clervoy, Jean-Francois; Gharib, Thierry; Gai, Frederic; Mora, Christophe
2016-12-01
Aircraft parabolic flights repetitively provide up to 23 seconds of reduced gravity during ballistic flight manoeuvres. Parabolic flights are used to conduct short microgravity investigations in Physical and Life Sciences and in Technology, to test instrumentation prior to space flights and to train astronauts before a space mission. The use of parabolic flights is complementary to other microgravity carriers (drop towers, sounding rockets), and preparatory to manned space missions on board the International Space Station and other manned spacecraft, such as Shenzhou and the future Chinese Space Station. After 17 years of using the Airbus A300 ZERO-G, the French company Novespace, a subsidiary of the ' Centre National d'Etudes Spatiales' (CNES, French Space Agency), based in Bordeaux, France, purchased a new aircraft, an Airbus A310, to perform parabolic flights for microgravity research in Europe. Since April 2015, the European Space Agency (ESA), CNES and the ` Deutsches Zentrum für Luft- und Raumfahrt e.V.' (DLR, the German Aerospace Center) use this new aircraft, the Airbus A310 ZERO-G, for research experiments in microgravity. The first campaign was a Cooperative campaign shared by the three agencies, followed by respectively a CNES, an ESA and a DLR campaign. This paper presents the new Airbus A310 ZERO-G and its main characteristics and interfaces for scientific experiments. The experiments conducted during the first European campaign are presented.
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78 FR 28627 - TA-W-80,340; TA-W-80,340A; TA-W-80,340B
2013-05-15
...] Bush Industries, Inc., Mason Drive Facility, Including On-Site Leased Workers From Morris Security...., Mason Drive Facility, Jamestown, New York (TA-W-80,340) and Bush Industries, Inc., Allen Street Facility... applicable to TA-W-80,340 is hereby issued as follows: All workers of Bush Industries, Inc., Mason Drive...
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2013-12-17
..., and accommodates side-by-side placement of LD-3 containers in the cargo compartment. The basic Airbus... availability of this excess maneuver capacity in case of extreme emergency such as upset recoveries or... factor must not be less than: (a) 2.5g for the EFCS normal state with the high lift devices retracted up...
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2011-04-06
... B4-600, B4-600R, and F4-600R Series Airplanes, and Model C4-605R Variant F Airplanes (Collectively... July 20, 2005; have been performed in service. (2) Airbus Model A300 B4-605R, B4-622R, F4-605R, and F4... C4-600R, and A300 F4-600R series airplanes (fitted with a trim tank), all serial numbers, except...
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International Nuclear Information System (INIS)
Javaux, Denis
2002-01-01
This paper describes a method for predicting the errors that may appear when human operators or users interact with systems behaving as finite state systems. The method is a generalization of a method used for predicting errors when interacting with autopilot modes on modern, highly computerized airliners [Proc 17th Digital Avionics Sys Conf (DASC) (1998); Proc 10th Int Symp Aviat Psychol (1999)]. A cognitive model based on spreading activation networks is used for predicting the user's model of the system and its impact on the production of errors. The model strongly posits the importance of implicit learning in user-system interaction and its possible detrimental influence on users' knowledge of the system. An experiment conducted with Airbus Industrie and a major European airline on pilots' knowledge of autopilot behavior on the A340-200/300 confirms the model predictions, and in particular the impact of the frequencies with which specific state transitions and contexts are experienced
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2010-10-01
... Airworthiness Directives; Airbus Model A300 B4-600, B4-600R, and F4-600R Series Airplanes, and Model A300 C4...; Model A300 B4-601, B4- 603, B4-620, B4-622, B4-605R, B4-622R, F4-605R, F4-622R, and C4-605R Variant F...-- Dated-- A300 series airplanes......... A300-32A0447..... April 22, 2004. A300 B4-600, B4-600R, and F4...
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New Space at Airbus Defence & Space to facilitate science missions
Boithias, Helene; Benchetrit, Thierry
2016-10-01
In addition to Airbus legacy activities, where Airbus satellites usually enable challenging science missions such as Venus Express, Mars Express, Rosetta with an historic landing on a comet, Bepi Colombo mission to Mercury and JUICE to orbit around Jupiter moon Ganymede, Swarm studying the Earth magnetic field, Goce to measure the Earth gravitational field and Cryosat to monitor the Earth polar ice, Airbus is now developing a new approach to facilitate next generation missions.After more than 25 years of collaboration with the scientists on space missions, Airbus has demonstrated its capacity to implement highly demanding missions implying a deep understanding of the science mission requirements and their intrinsic constraints such as- a very fierce competition between the scientific communities,- the pursuit of high maturity for the science instrument in order to be selected,- the very strict institutional budget limiting the number of operational missions.As a matter of fact, the combination of these constraints may lead to the cancellation of valuable missions.Based on that and inspired by the New Space trend, Airbus is developing an highly accessible concept called HYPE.The objective of HYPE is to make access to Space much more simple, affordable and efficient.With a standardized approach, the scientist books only the capacities he needs among the resources available on-board, as the HYPE satellites can host a large range of payloads from 1kg up to 60kg.At prices significantly more affordable than those of comparable dedicated satellite, HYPE is by far a very cost-efficient way of bringing science missions to life.After the launch, the scientist enjoys a plug-and-play access to two-way communications with his instrument through a secure high-speed portal available online 24/7.Everything else is taken care of by Airbus: launch services and the associated risk, reliable power supply, setting up and operating the communication channels, respect of space law
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2010-12-01
... require repetitive inspections and, as terminating action, the embodiment of Airbus Service Bulletins (SB... terminating action, the embodiment of Airbus Service Bulletins (SB) A300-57-0235 and A300-57-6088...
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Goupil, Ph.; Puyou, G.
2013-12-01
This paper presents a high-fidelity generic twin engine civil aircraft model developed by Airbus for advanced flight control system research. The main features of this benchmark are described to make the reader aware of the model complexity and representativeness. It is a complete representation including the nonlinear rigid-body aircraft model with a full set of control surfaces, actuator models, sensor models, flight control laws (FCL), and pilot inputs. Two applications of this benchmark in the framework of European projects are presented: FCL clearance using optimization and advanced fault detection and diagnosis (FDD).
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Airbus Boeingu vastu / tõlk. Kaie Ilves
2006-01-01
Saksamaa ja Prantsusmaa ühisettetvõtte Airbus A350 tüüpi pikamaalennuki ehitusfaasi peatamine on vallandanud juhatuses diskussiooni, kas lennukiehitus peaks saama riigilt finantstoetust, et suuta konkureerida oma USA rivaali Boeinguga võrdselt positsioonilt
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Ergonomic work analysis of airbus pilots job in Brazil.
Monteiro, Tathiana Passeri; Marques, Diego Cesar; Barbosa, Victor Gonçalves; Uatanabe, Priscila
2012-01-01
This article is the result of a case study of ergonomic work analysis carried out in a Brazilian airline company, focused on the safety of the activity of Airbus pilots from the company's national lines. The study was divided in three parts, each one with different approach. First step is how critical situations such as accidents and incidents are dealt with during flight. Then it comes to discuss about adversities found in the working place, the airbus cockpit, and the development of risk map. Last but not least, the study focused in how the irregular working journey compromises the biological clock of the pilots end may cause social issues.
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78 FR 8054 - Airworthiness Directives; Airbus Airplanes
2013-02-05
...-1321; Directorate Identifier 2011-NM-147-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... A310 series airplanes. The existing AD currently requires repetitive inspections for fatigue cracking... information at the FAA, Transport Airplane Directorate, 1601 Lind Avenue SW., Renton, WA. For information on...
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78 FR 40074 - Airworthiness Directives; Airbus Airplanes
2013-07-03
...-0465; Directorate Identifier 2012-NM-085-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... series airplanes. This proposed AD was prompted by a determination that oxygen generators installed on a... information at the FAA, Transport Airplane Directorate, 1601 Lind Avenue SW., Renton, WA. For information on...
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Yuan, Shunda; Chou, I-Ming; Burruss, Robert A.
2013-01-01
Elemental sulfur, as a transient intermediate compound, by-product, or catalyst, plays significant roles in thermochemical sulfate reduction (TSR) reactions. However, the mechanisms of the reactions in S-H2O-hydrocarbons systems are not clear. To improve our understanding of reaction mechanisms, we conducted a series of experiments between 200 and 340 °C for S-H2O-CH4, S-D2O-CH4, and S-CH4-1m ZnBr2 systems in fused silica capillary capsules (FSCC). After a heating period ranging from 24 to 2160 hours (hrs), the quenched samples were analyzed by Raman spectroscopy. Combined with the in situ Raman spectra collected at high temperatures and pressures in the S-H2O and S-H2O-CH4 systems, our results showed that (1) the disproportionation of sulfur in the S-H2O-CH4 system occurred at temperatures above 200 °C and produced H2S, SO42-, and possibly trace amount of HSO4-; (2) sulfate (and bisulfate), in the presence of sulfur, can be reduced by methane between 250 and 340 °C to produce CO2 and H2S, and these TSR temperatures are much closer to those of the natural system (2O-CH4 system may take place simultaneously, with TSR being favored at higher temperatures; and (4) in the system S-D2O-CH4, both TSR and the competitive disproportionation reactions occurred simultaneously at temperatures above 300 °C, but these reactions were very slow at lower temperatures. Our observation of methane reaction at 250 °C in a laboratory time scale suggests that, in a geologic time scale, methane may be destroyed by TSR reactions at temperatures > 200 °C that can be reached by deep drilling for hydrocarbon resources.
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78 FR 69318 - Airworthiness Directives; Rockwell Collins, Inc. Transponders
2013-11-19
... We invite you to send any written relevant data, views, or arguments about this proposal. Send your... with the transponders that could lead to increased pilot and air traffic controller workload as well as..., certificated in any category: (i) Airbus Models A319, A320, A330, A340; and (ii) Boeing Models B777, B747, MD...
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78 FR 40057 - Airworthiness Directives; Airbus Airplanes
2013-07-03
...-0467; Directorate Identifier 2013-NM-023-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... A321 series airplanes. This proposed AD was prompted by reports of certain sliding windows that were... from safely evacuating the airplane during an emergency. DATES: We must receive comments on this...
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76 FR 61555 - Airworthiness Directives; Airbus Airplanes
2011-10-05
... pieces unit welded, instead of 4 pieces unit with 3 welds (old design) as pictured in Appendix 1 of this... pre-modification 02447. Blue and Green. A300 airplanes post-modification 02447 Blue. A300-600 airplanes Blue. A310 airplanes Green. Table 2--Applicable Service Information Airbus Mandatory Service...
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77 FR 67263 - Airworthiness Directives; Airbus Airplanes
2012-11-09
... to correct an unsafe condition for the specified products. The MCAI states: During shop visit... first installed on an airplane: Before further flight, do the actions in Figure A-FBBAA-Sheet 03, Flow... Figure A-FBBAA-Sheet 02, Flow Chart, of Airbus Mandatory Service Bulletin A330-71-3025, excluding...
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77 FR 29207 - Airworthiness Directives; Airbus Airplanes
2012-05-17
... number 2. In addition, Airbus foresees a potential safety hazard for mechanics if seals are installed... provide an acceptable level of safety. We have not changed the AD in this regard. Explanation of... responsibilities among the various levels of government. For the reasons discussed above, I certify that this...
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77 FR 25930 - Airworthiness Directives; Airbus Airplanes
2012-05-02
...-2098, dated July 22, 2011; and Mandatory Service Bulletin A310-57-2099, dated July 22, 2011. The... A310-57-2099, dated July 22, 2011. (ii) If no cracking is found during the inspection required by... accordance with Accomplishment Instructions of Airbus Mandatory Service Bulletin A310-57-2099, dated July 22...
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2010-07-01
... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Introduction. 21.340 Section 21.340 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... Leaves of Absence § 21.340 Introduction. (a) General. VA may approve leaves of absence under certain...
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78 FR 22432 - Airworthiness Directives; Airbus Airplanes
2013-04-16
... electrical rudder], through Airbus Service Bulletin (SB) A330-27-3176, --software standard P12A/M21A on FCPC.... Since we issued that AD, we have determined that new software standards for the flight control primary.... This proposed AD would require that operators modify or replace all three FCPCs with new software...
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77 FR 17327 - Airworthiness Directives; Airbus Airplanes
2012-03-26
... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2011-1087; Directorate Identifier 2011-NM-032-AD; Amendment 39-16967; AD 2012-04-11] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes Correction In rule document 2012-5859 appearing on pages 14679-14681...
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77 FR 46935 - Airworthiness Directives; Airbus Airplanes
2012-08-07
... Instructions of Airbus Mandatory Service Bulletin A310-57-2099, dated July 22, 2011. (ii) If no cracking is... Service Bulletin A310-57-2099, dated July 22, 2011. (h) Bolt Replacement at Slat 2 Track 4 and Track 7... Mandatory Service Bulletin A310-57-2099, dated July 22, 2011. (l) Material Incorporated by Reference (1) The...
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An economic and financial review of Airbus Indsutrie
1990-09-04
This report was prepared for the International Trade Administration of the U.S. Department of Commerce (DOC). It examines the economics of Airbus Industre (AI) civil transport programs and the potential effects of AI's presence on both the market for...
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340 Facility maintenance implementation plan
International Nuclear Information System (INIS)
1995-03-01
This Maintenance Implementation Plan (MIP) has been developed for maintenance functions associated with the 340 Facility. This plan is developed from the guidelines presented by Department of Energy (DOE) Order 4330.4B, Maintenance Management Program (DOE 1994), Chapter II. The objective of this plan is to provide baseline information for establishing and identifying Westinghouse Hanford Company (WHC) conformance programs and policies applicable to implementation of DOE order 4330.4B guidelines. In addition, this maintenance plan identifies the actions necessary to develop a cost-effective and efficient maintenance program at the 340 Facility. Primary responsibility for the performance and oversight of maintenance activities at the 340 Facility resides with Westinghouse Hanford Company (WHC). Maintenance at the 340 Facility is performed by ICF-Kaiser Hanford (ICF-KH) South Programmatic Services crafts persons. This 340 Facility MIP provides interface requirements and responsibilities as they apply specifically to the 340 Facility. This document provides an implementation schedule which has been developed for items considered to be deficient or in need of improvement. The discussion sections, as applied to implementation at the 340 Facility, have been developed from a review of programs and practices utilizing the graded approach. Biennial review and additional reviews are conducted as significant programmatic and mission changes are made. This document is revised as necessary to maintain compliance with DOE requirements
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340 Facility maintenance implementation plan
Energy Technology Data Exchange (ETDEWEB)
NONE
1995-03-01
This Maintenance Implementation Plan (MIP) has been developed for maintenance functions associated with the 340 Facility. This plan is developed from the guidelines presented by Department of Energy (DOE) Order 4330.4B, Maintenance Management Program (DOE 1994), Chapter II. The objective of this plan is to provide baseline information for establishing and identifying Westinghouse Hanford Company (WHC) conformance programs and policies applicable to implementation of DOE order 4330.4B guidelines. In addition, this maintenance plan identifies the actions necessary to develop a cost-effective and efficient maintenance program at the 340 Facility. Primary responsibility for the performance and oversight of maintenance activities at the 340 Facility resides with Westinghouse Hanford Company (WHC). Maintenance at the 340 Facility is performed by ICF-Kaiser Hanford (ICF-KH) South Programmatic Services crafts persons. This 340 Facility MIP provides interface requirements and responsibilities as they apply specifically to the 340 Facility. This document provides an implementation schedule which has been developed for items considered to be deficient or in need of improvement. The discussion sections, as applied to implementation at the 340 Facility, have been developed from a review of programs and practices utilizing the graded approach. Biennial review and additional reviews are conducted as significant programmatic and mission changes are made. This document is revised as necessary to maintain compliance with DOE requirements.
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78 FR 46536 - Airworthiness Directives; Airbus Airplanes
2013-08-01
...-0668; Directorate Identifier 2013-NM-017-AD] RIN 2120-AA64 Airworthiness Directives; Airbus Airplanes... B4-600R series airplanes. This proposed AD was prompted by reports of cracks found in the bottom wing... at the FAA, Transport Airplane Directorate, 1601 Lind Avenue SW., Renton, WA. For information on the...
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Using 340B drug discounts to provide a financially sustainable medication discharge service.
Wu, Timothy; Williams, Carla; Vranek, Kathryn; Mattingly, T Joseph
2018-03-27
The 340B Drug Pricing Program was intended to stretch federal resources by providing significant discounts to covered entities providing care to underserved populations. Program implementation and evidence of expanding services to higher income patients has brought more scrutiny and calls for elimination of the program. While additional review and reform may be warranted, profitability from 340B discounts enables covered entities to provide additional services that may not be feasible in absence of the program. This case report demonstrates one institution's use of 340B discounts to financially justify providing bedside medication delivery services for patients at the time of discharge from an inpatient admission. A simple financial model was developed using hospital data and inputs from available literature to estimate gross profit and earnings before interest, taxes, depreciation, and amortization (EBITDA) with and without 340B discounts. Without the 340B drug price discounts, the service would operate at a financial loss, and further investigation must be done to determine whether other clinical or economic benefits would warrant discharge medication delivery at the institution. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.
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Reliability analysis of Airbus A-330 computer flight management system
Fajmut, Metod
2010-01-01
Diploma thesis deals with digitized, computerized flight control system »Fly-by-wire« and security aspects of the computer system of an aircraft Airbus A330. As for space and military aircraft structures is also in commercial airplanes, much of the financial contribution devoted to reliability. Conventional aircraft control systems have, and some are still, to rely on mechanical and hydraulic connections between the controls on aircraft operated by the pilot and control surfaces. But newer a...
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77 FR 7007 - Airworthiness Directives; Airbus Airplanes
2012-02-10
... Gear Bogie Beams and A340-500/600 Centre Landing Gear Bogie Beams, cracks in the Bogie Pivot Pin (BPP... degradation * * * of the BPP [and cracks and damages of the bushes], as applicable to aeroplane model, and the...
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340 Waste Handling Facility interim safety basis
International Nuclear Information System (INIS)
Bendixsen, R.B.
1995-01-01
This document establishes the interim safety basis (ISB) for the 340 Waste Handling Facility (340 Facility). An ISB is a documented safety basis that provides a justification for the continued operation of the facility until an upgraded final safety analysis report is prepared that complies with US Department of Energy (DOE) Order 5480.23, Nuclear Safety Analysis Reports. The ISB for the 340 Facility documents the current design and operation of the facility. The 340 Facility ISB (ISB-003) is based on a facility walkdown and review of the design and operation of the facility, as described in the existing safety documentation. The safety documents reviewed, to develop ISB-003, include the following: OSD-SW-153-0001, Operating Specification Document for the 340 Waste Handling Facility (WHC 1990); OSR-SW-152-00003, Operating Limits for the 340 Waste Handling Facility (WHC 1989); SD-RE-SAP-013, Safety Analysis Report for Packaging, Railroad Liquid Waste Tank Cars (Mercado 1993); SD-WM-TM-001, Safety Assessment Document for the 340 Waste Handling Facility (Berneski 1994a); SD-WM-SEL-016, 340 Facility Safety Equipment List (Berneski 1992); and 340 Complex Fire Hazard Analysis, Draft (Hughes Assoc. Inc. 1994)
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2010-04-01
... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Definition. 340.3 Section 340.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE STIMULANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE General Provisions § 340.3 Definition. As used in...
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2010-07-01
... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Taxation. 340.3 Section 340.3 Money... COMPETITIVE BIDDING § 340.3 Taxation. The income derived from the bonds will be subject to all taxes imposed... excise taxes, whether Federal or State, but will be exempt from all taxation now or hereafter imposed on...
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21 CFR 573.340 - Diatomaceous earth.
2010-04-01
... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Diatomaceous earth. 573.340 Section 573.340 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additive Listing § 573.340 Diatomaceous earth. (a) Identity. The additive consists of siliceous skeletal...
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Performance assessment of a hybrid electric-powered long-range commercial airliner
Zöld, Thomas
2012-01-01
Despite the recent increase in the amount of smaller electric general aviation aircrafts, a fully electric airliner is not likely to fly in the near future. Partially inspired by the automotive industry’s success with the hybrid car, this thesis investigated the feasibility of an electric-hybrid propulsion system for an Airbus A340-600 on a long-haul flight and its effect on the aircraft’s performance. First, an analysis was done of the reference aircraft, A340-600, using conventional propuls...
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9 CFR 3.40 - Terminal facilities.
2010-01-01
... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Terminal facilities. 3.40 Section 3.40... Pigs and Hamsters Transportation Standards § 3.40 Terminal facilities. No person subject to the Animal... animal holding areas of a terminal facility where shipments of live guinea pigs or hamsters are...
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Weight reductions for the airbus A380; postbuckling of the A380 VTP skin panels
Kroese, R.
2014-01-01
The skin panels of the Vertical Tail Plane (VTP) are the largest single piece composite components assembled on the Airbus A380. By allowing postbuckling to these skin panels might result in severe weight reductions for the VTP of the A380. The goal of the study is to give an indication of possible
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7 CFR 1205.340 - Confidential treatment.
2010-01-01
... 7 Agriculture 10 2010-01-01 2010-01-01 false Confidential treatment. 1205.340 Section 1205.340 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Cotton Research and Promotion Order Reports, Books, and Records § 1205.340 Confidential treatment. All...
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340 Facility compliance assessment
International Nuclear Information System (INIS)
English, S.L.
1993-10-01
This study provides an environmental compliance evaluation of the RLWS and the RPS systems of the 340 Facility. The emphasis of the evaluation centers on compliance with WAC requirements for hazardous and mixed waste facilities, federal regulations, and Westinghouse Hanford Company (WHC) requirements pertinent to the operation of the 340 Facility. The 340 Facility is not covered under either an interim status Part A permit or a RCRA Part B permit. The detailed discussion of compliance deficiencies are summarized in Section 2.0. This includes items of significance that require action to ensure facility compliance with WAC, federal regulations, and WHC requirements. Outstanding issues exist for radioactive airborne effluent sampling and monitoring, radioactive liquid effluent sampling and monitoring, non-radioactive liquid effluent sampling and monitoring, less than 90 day waste storage tanks, and requirements for a permitted facility
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76 FR 22308 - Airworthiness Directives; Airbus Model A340-541 and -642 Airplanes
2011-04-21
...: * * * * * * * * [S]ome Allowable Damage Limits and Repairs published in SRM Chapters 57-61-12 PB101 and 57-61-12...-validated SRM'' used in this AD text refers to the SRM chapters mentioned above. In order to prevent... strength re- valuation, some Allowable Damage Limits (ADL) and Repairs of holes and delaminations in...
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46 CFR 340.5 - Containers and chassis.
2010-10-01
... 46 Shipping 8 2010-10-01 2010-10-01 false Containers and chassis. 340.5 Section 340.5 Shipping... ALLOCATION OF SHIPPING SERVICES, CONTAINERS AND CHASSIS, AND PORT FACILITIES AND SERVICES FOR NATIONAL SECURITY AND NATIONAL DEFENSE RELATED OPERATIONS § 340.5 Containers and chassis. (a) When a defense agency...
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46 CFR 197.340 - Breathing gas supply.
2010-10-01
... 46 Shipping 7 2010-10-01 2010-10-01 false Breathing gas supply. 197.340 Section 197.340 Shipping... GENERAL PROVISIONS Commercial Diving Operations Equipment § 197.340 Breathing gas supply. (a) A primary breathing gas supply for surface-supplied diving must be sufficient to support the following for the...
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7 CFR 1.340 - Stay pending appeal.
2010-01-01
... 7 Agriculture 1 2010-01-01 2010-01-01 false Stay pending appeal. 1.340 Section 1.340 Agriculture... Hearings Under the Program Fraud Civil Remedies Act of 1986 § 1.340 Stay pending appeal. (a) A decision is stayed automatically pending disposition of a motion for reconsideration or of an appeal to the judicial...
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7 CFR 58.340 - Printing and packaging.
2010-01-01
... 7 Agriculture 3 2010-01-01 2010-01-01 false Printing and packaging. 58.340 Section 58.340... Procedures § 58.340 Printing and packaging. Printing and packaging of consumer size containers of butter... packaging equipment should be provided. The outside cartons should be removed from bulk butter in a room...
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2010-04-01
... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Scope. 340.1 Section 340.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE STIMULANT... stimulant drug product in a form suitable for oral administration is generally recognized as safe and...
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21 CFR 172.340 - Fish protein isolate.
2010-04-01
... Special Dietary and Nutritional Additives § 172.340 Fish protein isolate. (a) The food additive fish... accordance with recognized good manufacturing practice for fish to be used as human food. (4) The additive... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Fish protein isolate. 172.340 Section 172.340 Food...
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78 FR 77611 - Special Conditions: Airbus, A350-900 Series Airplane; High Speed Protection System
2013-12-24
... initiated three seconds after operation of the high speed warning system by application of a load of 1.5g (0...-1001; Notice No. 25-13-35-SC] Special Conditions: Airbus, A350-900 Series Airplane; High Speed...-speed protection system. The applicable airworthiness regulations do not contain adequate or appropriate...
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Airbus A320 NEO Base Maintenance Concept SAS Operations
Dafgård, Oscar
2017-01-01
Detta arbete har utförts tillsammans med SAS, för att undersöka om ett base maintenance koncept med ett intervall på 36 månader skulle vara mer kostnadseffektivt än 24 månader för deras nya Airbus A320 NEO flotta. SAS, precis som alla andra flygbolag utnyttjar sina flygplan på sina egna och specifika vis. Eftersom inga flygbolag opererar på samma sätt kan inte heller underhållet skötas på samma sätt för en specifik flygplanstyp. Underhållsprogrammet behövde därför ses över för att optimeras g...
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21 CFR 340.10 - Stimulant active ingredient.
2010-04-01
... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Stimulant active ingredient. 340.10 Section 340.10 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE STIMULANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredient § 340.10...
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41 CFR 102-34.340 - Do we need a fleet management information system?
2010-07-01
... management information system? 102-34.340 Section 102-34.340 Public Contracts and Property Management Federal... VEHICLE MANAGEMENT Federal Fleet Report § 102-34.340 Do we need a fleet management information system? Yes, you must have a fleet management information system at the department or agency level that — (a...
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Development of a metrics dashboard for monitoring involvement in the 340B Drug Pricing Program.
Karralli, Rusol; Tipton, Joyce; Dumitru, Doina; Scholz, Lisa; Masilamani, Santhi
2015-09-01
An electronic tool to support hospital organizations in monitoring and addressing financial and compliance challenges related to participation in the 340B Drug Pricing Program is described. In recent years there has been heightened congressional and regulatory scrutiny of the federal 340B program, which provides discounted drug prices on Medicaid-covered drugs to safety net hospitals and other 340B-eligible healthcare organizations, or "covered entities." Historically, the 340B program has lacked a metrics-driven reporting framework to help covered entities capture the value of 340B program involvement, community benefits provided to underserved populations, and costs associated with compliance with 340B eligibility requirements. As part of an initiative by a large health system to optimize its 340B program utilization and regulatory compliance efforts, a team of pharmacists led the development of an electronic dashboard tool to help monitor 340B program activities at the system's 340B-eligible facilities. After soliciting input from an array of internal and external 340B program stakeholders, the team designed the dashboard and associated data-entry tools to facilitate the capture and analysis of 340B program-related data in four domains: cost savings and revenue, program maintenance costs, community benefits, and compliance. A large health system enhanced its ability to evaluate and monitor 340B program-related activities through the use of a dashboard tool capturing key metrics on cost savings achieved, maintenance costs, and other aspects of program involvement. Copyright © 2015 by the American Society of Health-System Pharmacists, Inc. All rights reserved.
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340 and 310 drawing field verification
International Nuclear Information System (INIS)
Langdon, J.
1996-01-01
The purpose of the drawing field verification work plan is to provide reliable drawings for the 310 Treated Effluent Disposal Facility (TEDF) and 340 Waste Handling Facility (340 Facility). The initial scope of this work plan is to provide field verified and updated versions of all the 340 Facility essential drawings. This plan can also be used for field verification of any other drawings that the facility management directs to be so updated. Any drawings revised by this work plan will be issued in an AutoCAD format
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29 CFR 779.340 - Out-of-State customers.
2010-07-01
... 29 Labor 3 2010-07-01 2010-07-01 false Out-of-State customers. 779.340 Section 779.340 Labor... State § 779.340 Out-of-State customers. Whether the sale or service is made to an out-of-State customer is a question of fact. In order for a customer to be considered an out-of-State customer, some...
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2012-12-19
...-1207; Notice No. 25-12-09-SC] Special Conditions: Airbus, A350-900 Series Airplane; Flight Envelope... or unusual design features associated with flight envelope protection in icing and non- icing..., during failure conditions (which are not shown to be extremely improbable), the requirements of Title 14...
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Lifescience Database Archive (English)
Full Text Available SL (Link to library) SLA340 (Link to dictyBase) - - - Contig-U16510-1 - (Link to Or...iginal site) - - SLA340Z 466 - - - - Show SLA340 Library SL (Link to library) Clone ID SLA340 (Link to dicty...Base) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16510-1 Original site URL http://dictycdb.b.... 2 Translated Amino Acid sequence ---CGKPSPIPTCTRKLSPISICIIKLCPIFICITKLCSIYICTISICIIFICIICSNYS CNYNCNYSCNYN...qpqlqlqlqlqpqpqlqpqlqpq lplkfnqktffikyhynnffnnnsikk*y*kspffl Frame C: ---CGKPSPIPTCTRKLSPISICIIKLCPIFICITKLCSIYICT
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Passivation Strategies on Board Airbus ds Leo Pcdus
Directory of Open Access Journals (Sweden)
Lapeña Emilio
2017-01-01
This paper deals with the different strategies followed in the Airbus DS LEO PCDUs regarding the implementation of the passivation function in several LEO missions with different architectures (DET and MPPT solar array power conditioning. In the selection of the solution implemented in the frame of every mission, a key driver is the degree of advance in the test performed over flight representative battery modules regarding their safe behavior when deeply depleted after a long period in orbit with the passivation applied over the spacecraft.
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340 Facility secondary containment and leak detection
International Nuclear Information System (INIS)
Bendixsen, R.B.
1995-01-01
This document presents a preliminary safety evaluation for the 340 Facility Secondary Containment and Leak Containment system, Project W-302. Project W-302 will construct Building 340-C which has been designed to replace the current 340 Building and vault tank system for collection of liquid wastes from the Pacific Northwest Laboratory buildings in the 300 Area. This new nuclear facility is Hazard Category 3. The vault tank and related monitoring and control equipment are Safety Class 2 with the remainder of the structure, systems and components as Safety Class 3 or 4
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Energy efficiency improvements in air traffic: The case of Airbus A320 in Spain
International Nuclear Information System (INIS)
Cansino, José M.; Román, Rocío
2017-01-01
Structural improvements in aircraft design, seeking to improve energy efficiency, can significantly reduce greenhouse gas emissions (GHG) by reducing reduced fuel consumption. This research reviews improvements with the introduction of a structural component known as 'winglet;' these are positioned at the top of the aircraft wing, and increased Airbus Group A320 sales. Data used are taken from air traffic in Spain for the 2010–2014 period with projections being made for 2020. The results show that winglets reduce CO_2 equivalent emissions associated with Spain's air transport for the 2015–2020 period between 66.29 and 59.56 Gg. depending on the scenario considered in 2020. - Highlights: • Spanish air traffic is considered a key-GHG emission sector. • The aviation industry has drastically reduced its emissions. • To what extent could improved model to reduce fuel consumption and polluting emissions? • A320 Neo, A330 Neo and A380 Neo models are in the process of industrialisation. • Objectives fixed by Air Transport Action Group for 2020 are relevant.
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340 waste handling facility interim safety basis
Energy Technology Data Exchange (ETDEWEB)
VAIL, T.S.
1999-04-01
This document presents an interim safety basis for the 340 Waste Handling Facility classifying the 340 Facility as a Hazard Category 3 facility. The hazard analysis quantifies the operating safety envelop for this facility and demonstrates that the facility can be operated without a significant threat to onsite or offsite people.
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340 waste handling facility interim safety basis
International Nuclear Information System (INIS)
VAIL, T.S.
1999-01-01
This document presents an interim safety basis for the 340 Waste Handling Facility classifying the 340 Facility as a Hazard Category 3 facility. The hazard analysis quantifies the operating safety envelop for this facility and demonstrates that the facility can be operated without a significant threat to onsite or offsite people
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40 CFR 96.340 - State trading budgets.
2010-07-01
... 40 Protection of Environment 20 2010-07-01 2010-07-01 false State trading budgets. 96.340 Section...) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR NOX Ozone Season Allowance Allocations § 96.340 State trading budgets. (a) Except as provided in...
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7 CFR 340.7 - Marking and identity.
2010-01-01
... 7 Agriculture 5 2010-01-01 2010-01-01 false Marking and identity. 340.7 Section 340.7 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE... identity. (a) Any regulated article to be imported other than by mail, shall, at the time of importation...
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2011-11-28
... Model 737-100, -200, -300, -400, and -500 series airplanes, a one-time detailed inspection is added to... Information Initial Compliance Time (i) For all Model 737-100, -200, -200C, -300, -400, and -500 series... by paragraph (r) of this AD. If any fastener is missing, before further flight, repair using a method...
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40 CFR 97.340 - State trading budgets.
2010-07-01
... 40 Protection of Environment 20 2010-07-01 2010-07-01 false State trading budgets. 97.340 Section...) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR NOX Ozone Season Allowance Allocations § 97.340 State trading budgets. (a) Except as provided in paragraph (b) of this section, the State...
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The DoD C-17 Versus the Boeing 777. A Comparison of Acquisition and Development
1999-10-01
Standard Encyclopedia (New York: Unicorn Publishers, 1955), 102-103. 9. The World Book Encyclopedia (Kansas City, MO: Field Enterprises Educational...costs about $25.25 per mile to operate--including insurance, administration, and financing . The amount is similar for the MD-11 and Airbus A340-300X, 9...resources that include investments, income from operations (airplane sales), or outside financing . Although Boeing customarily receives a deposit
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340 nm pulsed UV LED system for europium-based time-resolved fluorescence detection of immunoassays
Rodenko, Olga; Fodgaard, Henrik; Tidemand-Lichtenberg, Peter; Petersen, Paul Michael; Pedersen, Christian
2016-01-01
We report on the design, development and investigation of an optical system based on UV light emitting diode (LED) excitation at 340 nm for time-resolved fluorescence detection of immunoassays. The system was tested to measure cardiac marker Troponin I with a concentration of 200 ng/L in immunoassay. The signal-to-noise ratio was comparable to state-of-the-art Xenon flash lamp based unit with equal excitation energy and without overdriving the LED. We performed a comparative study of the flas...
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21 CFR 340.50 - Labeling of stimulant drug products.
2010-04-01
... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Labeling of stimulant drug products. 340.50 Section 340.50 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE STIMULANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Labeling § 340.50...
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Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D
DEFF Research Database (Denmark)
Holmskov, U; Mollenhauer, J; Madsen, J
1999-01-01
in a soluble form and in association with the membranes of alveolar macrophages. The primary structure of gp-340 has been established by molecular cloning, which yielded a 7,686-bp cDNA sequence encoding a polypeptide chain of 2, 413 amino acids. The domain organization features 13 scavenger receptor cysteine...... in a way that suggested capping, whereas other macrophages showed strong intracellular staining within the phagosome/phagolysosome compartments. In some macrophages, SP-D and gp-340 were located in the same cellular compartment. Immunoreactive gp-340 was also found in epithelial cells of the small...
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340 waste handling complex: Deactivation project management plan
International Nuclear Information System (INIS)
Stordeur, R.T.
1998-01-01
This document provides an overview of the strategy for deactivating the 340 Waste Handling Complex within Hanford's 300 Area. The plan covers the period from the pending September 30, 1998 cessation of voluntary radioactive liquid waste (RLW) transfers to the 340 Complex, until such time that those portions of the 340 Complex that remain active beyond September 30, 1998, specifically, the Retention Process Sewer (RPS), can also be shut down and deactivated. Specific activities are detailed and divided into two phases. Phase 1 ends in 2001 after the core RLW systems have been deactivated. Phase 2 covers the subsequent interim surveillance of deactivated and stand-by components during the period of continued RPS operation, through the final transfer of the entire 340 Complex to the Environmental Restoration Contractor. One of several possible scenarios was postulated and developed as a budget and schedule planning case
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Pletser, Vladimir; Rouquette, Sebastien; Friedrich, Ulrike; Clervoy, Jean-Francois; Gharib, Thierry; Gai, Frederic; Mora, Christophe
2015-09-01
Aircraft parabolic flights repetitively provide up to 23 s of reduced gravity during ballistic flight manoeuvres. Parabolic flights are used to conduct short microgravity investigations in Physical and Life Sciences and in Technology, to test instrumentation prior to space flights and to train astronauts before a space mission. The use of parabolic flights is complementary to other microgravity carriers (drop towers, sounding rockets), and preparatory to manned space missions on board the International Space Station and other manned spacecraft, such as Shenzhou and the Chinese Space Station CSS. The European Space Agency (ESA), the 'Centre National d'Etudes Spatiales' (CNES, French Space Agency) and the 'Deutsches Zentrum für Luft- und Raumfahrt e.V.' (DLR, the German Aerospace Centre) have used the Airbus A300 ZERO-G for research experiments in microgravity, and at Moon and Mars gravity levels, from 1997 until October 2014. The French company Novespace, a subsidiary of CNES, based in Bordeaux, France, is in charge of the organisation of Airbus A300 ZERO-G flights. A total of 104 parabolic flight campaigns have been organised by ESA, CNES and DLR since 1997, including 38 ESA, 34 CNES and 23 DLR microgravity campaigns, two Joint European ESA-CNES-DLR Partial-g Parabolic Flight Campaigns, and seven ESA Student campaigns. After 17 years of good and loyal services, this European workhorse for microgravity research in parabolic flights has been retired. The successor aircraft, the Airbus A310 ZERO-G, is being prepared for a first ESA-CNES-DLR cooperative campaign in Spring 2015. This paper looks back over 17 years of microgravity research in parabolic flights with the A300 ZERO-G, and introduces the new A310 ZERO-G that will be used from 2015 onwards.
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miR-340 alleviates chemoresistance of osteosarcoma cells by targeting ZEB1.
Yan, Haibin; Zhang, Bingyun; Fang, Chongbin; Chen, Liqiu
2018-06-01
Chemoresistance during treatment of osteosarcoma (OS) is attracting more and more attention as the main clinical obstacle. The purpose of this study was to elucidate the role of miR-340 in chemoresistance of OS. Plasmid construction and transfection, miRNA arrays, PCR analyses, and western blot analysis, as well as MTT, apoptosis, and luciferase assays were carried out in MG-63 cells and MG-63/cisplatin (DDP)-resistant cells. The results showed that miR-340 was downregulated in OS tissues and drug-resistant OS cells. Moreover, a negative correlation was observed between miR-340 and ZEB1 expression in OS tissues. Forced expression of miR-340 in drug-resistant OS cells significantly reduced multidrug resistance-1 and P-gp expression. Overexpression of miR-340 enhanced sensitivity to DDP by inhibiting viability and promoting apoptosis. The luciferase assay and western blot analysis identified ZEB1 as a direct target of miR-340, and miR-340 negatively regulated ZEB1 expression. Ectopic expression of ZEB1 reversed the effects of miR-340 on P-gp expression, cell viability, and apoptosis. miR-340 alleviated chemoresistance of OS cells by targeting ZEB1. Our results indicate that targeting miR-340 may be a potential therapeutic approach to treat drug-resistant OS.
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Indriyanto, Reza Relen; Wandebori, Harimukti; Astuti, Novika Candra
2013-01-01
PT Dirgantara Indonesia (PT DI) is one of the aircraft manufacturing companies in Indonesia. The tight of competition in aerospace industry needs to improve its performance to gain niche market. Therefore, Ministry State of Own Enterprises has instructed PT Perusahaan Pengelola Aset (PT PPA) and PT DI to restructure and revitalize company with supported by Airbus Military as a strategic alliance partner, in order to increase the performance of production capacity, aircraft sales, and financia...
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Interpretation of a Variable Reflection Nebula Associated with HBC 340 and HBC 341 in NGC 1333
Energy Technology Data Exchange (ETDEWEB)
Dahm, S. E. [U.S. Naval Observatory, Flagstaff Station, 10391 West Naval Observatory Road, Flagstaff, AZ 86005-8521 (United States); Hillenbrand, L. A. [Department of Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States)
2017-11-01
We present multi-epoch, R -band imaging obtained from the Palomar Transient Factory of a small, fan-shaped reflection nebula in NGC 1333 that experiences prominent brightness fluctuations. Photometry of HBC 340 (K7e) and HBC 341 (M5e), a visual pair of late-type, young stellar objects lying near the apex of the nebula, demonstrates that while both are variable, the former has brightened by more than two magnitudes following a deep local minimum in 2014 September. Keck high-dispersion ( R ∼ 45,000–66,000), optical spectroscopy of HBC 340 suggests that the protostar is a spectroscopic binary (HBC 340Aa + HBC 340Ab). Both HBC 340 and HBC 341 exhibit strong H α and forbidden line emission, consistent with accretion and outflow. We conclude that the brightness fluctuations in the reflection nebula represent light echos produced by varying incident radiation emanating from HBC 340. The short-term variability observed in the protostar is attributed to irregular accretion activity, while correlated, dipping behavior on a several hundred day timescale may be due to eclipse-like events caused by orbiting circumstellar material. Archival Hubble Space Telescope imaging of the region reveals a second, faint (F814W ∼ 20.3 mag) companion to HBC 340 that lies 1.″02 (∼235 au) east of the protostar. If associated, this probable substellar mass object (20–50 Jupiter masses), HBC 340B, is likely unrelated to the observed brightness variations. The sustained brightening of HBC 340 since late 2014 can be explained by an EXor-like outburst, the recovery from a long duration eclipse event caused by obscuring circumstellar dust, or by the gradual removal of extincting material from along the line of sight. Our analysis here favors one of the extinction scenarios.
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Interpretation of a Variable Reflection Nebula Associated with HBC 340 and HBC 341 in NGC 1333
International Nuclear Information System (INIS)
Dahm, S. E.; Hillenbrand, L. A.
2017-01-01
We present multi-epoch, R -band imaging obtained from the Palomar Transient Factory of a small, fan-shaped reflection nebula in NGC 1333 that experiences prominent brightness fluctuations. Photometry of HBC 340 (K7e) and HBC 341 (M5e), a visual pair of late-type, young stellar objects lying near the apex of the nebula, demonstrates that while both are variable, the former has brightened by more than two magnitudes following a deep local minimum in 2014 September. Keck high-dispersion ( R ∼ 45,000–66,000), optical spectroscopy of HBC 340 suggests that the protostar is a spectroscopic binary (HBC 340Aa + HBC 340Ab). Both HBC 340 and HBC 341 exhibit strong H α and forbidden line emission, consistent with accretion and outflow. We conclude that the brightness fluctuations in the reflection nebula represent light echos produced by varying incident radiation emanating from HBC 340. The short-term variability observed in the protostar is attributed to irregular accretion activity, while correlated, dipping behavior on a several hundred day timescale may be due to eclipse-like events caused by orbiting circumstellar material. Archival Hubble Space Telescope imaging of the region reveals a second, faint (F814W ∼ 20.3 mag) companion to HBC 340 that lies 1.″02 (∼235 au) east of the protostar. If associated, this probable substellar mass object (20–50 Jupiter masses), HBC 340B, is likely unrelated to the observed brightness variations. The sustained brightening of HBC 340 since late 2014 can be explained by an EXor-like outburst, the recovery from a long duration eclipse event caused by obscuring circumstellar dust, or by the gradual removal of extincting material from along the line of sight. Our analysis here favors one of the extinction scenarios.
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40 CFR 1033.340 - Suspension and revocation of certificates of conformity.
2010-07-01
... certificates of conformity. 1033.340 Section 1033.340 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Production Line Testing and Audit Programs § 1033.340 Suspension and revocation of certificates of conformity... conformity is automatically suspended for any locomotive that fails a production line test pursuant to § 1033...
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Do we need an Airbus of the nuclear industry?
International Nuclear Information System (INIS)
Freed, J.; Allen, T.; Nordhaus, T.; Lovering, J.
2017-01-01
Facing cheap fossil energies and more and more available renewable energies, nuclear energy has to reinvent itself to recover competitiveness. Small reactors, able to be built quickly and to ensure economies of scale, might be the next technological breakthrough. The need for change and innovation is so strong in the nuclear sector that it may imply the creation of an international consortium similar to the Airbus partnership that could merge reactor manufacturers and gather all their technological and financial means towards a unique goal reinventing the manufacturing of reactors to adapt it to small reactors. (A.C.)
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Optimal flight altitude and flight routes with respect to environmental and economical aspects
Energy Technology Data Exchange (ETDEWEB)
Nodorp, D.; Sausen, R.; Land, C. [Deutsche Forschungsanstalt fuer Luft- und Raumfahrt e.V. (DLR), Oberpfaffenhofen (Germany). Inst. fuer Physik der Atmosphaere; Deidewig, F. [Deutsche Forschungsanstalt fuer Luft- und Raumfahrt e.V. (DLR), Koeln (Germany). Inst. fuer Antriebstechnik
1997-12-31
A flight routing method is presented. In addition to conventional minimization of travel time and/or fuel consumption it also takes into account the environmental impact of the aircraft emissions on the climate system. In the process the ECHAM general circulation model is used to trace the pollutants after release, estimate their potential to cause damage and to weight this environmental relative to the economical aspect. Some case studies are presented for an Airbus A340 in the North Atlantic flight corridor. (author) 6 refs.
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Optimal flight altitude and flight routes with respect to environmental and economical aspects
Energy Technology Data Exchange (ETDEWEB)
Nodorp, D; Sausen, R; Land, C [Deutsche Forschungsanstalt fuer Luft- und Raumfahrt e.V. (DLR), Oberpfaffenhofen (Germany). Inst. fuer Physik der Atmosphaere; Deidewig, F [Deutsche Forschungsanstalt fuer Luft- und Raumfahrt e.V. (DLR), Koeln (Germany). Inst. fuer Antriebstechnik
1998-12-31
A flight routing method is presented. In addition to conventional minimization of travel time and/or fuel consumption it also takes into account the environmental impact of the aircraft emissions on the climate system. In the process the ECHAM general circulation model is used to trace the pollutants after release, estimate their potential to cause damage and to weight this environmental relative to the economical aspect. Some case studies are presented for an Airbus A340 in the North Atlantic flight corridor. (author) 6 refs.
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Bani-Salameh, Zakaria A.; Kabilan, Muhammad K.; Bani-Salalmeh, Lina
2011-01-01
A multimedia English for Specific Purposes (ESP) programme was developed to train flight attendants. The programme comprised of two units. Unit one is listening comprehension, which provides the flight attendants' with specific information of Airbus A340. Unit two is reading comprehension, which provides the flight attendants with the emergency…
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Innate immunity glycoprotein gp-340 variants may modulate human susceptibility to dental caries
Directory of Open Access Journals (Sweden)
Johansson Ingegerd
2007-06-01
Full Text Available Abstract Background Bacterial adhesion is an important determinant of colonization and infection, including dental caries. The salivary scavenger receptor cysteine-rich glycoprotein gp-340, which mediates adhesion of Streptococcus mutans (implicated in caries, harbours three major size variants, designated gp-340 I to III, each specific to an individual saliva. Here we have examined the association of the gp-340 I to III polymorphisms with caries experience and adhesion of S. mutans. Methods A case-referent study was performed in 12-year-old Swedish children with high (n = 19 or low (n = 19 caries experiences. We measured the gp-340 I to III saliva phenotypes and correlated those with multiple outcome measures for caries experience and saliva adhesion of S. mutans using the partial least squares (PLS multivariate projection technique. In addition, we used traditional statistics and 2-year caries increment to verify the established PLS associations, and bacterial adhesion to purified gp-340 I to III proteins to support possible mechanisms. Results All except one subject were typed as gp-340 I to III (10, 23 and 4, respectively. The gp-340 I phenotype correlated positively with caries experience (VIP = 1.37 and saliva adhesion of S. mutans Ingbritt (VIP = 1.47. The gp-340 II and III phenotypes tended to behave in the opposite way. Moreover, the gp-340 I phenotype tended to show an increased 2-year caries increment compared to phenotypes II/III. Purified gp-340 I protein mediated markedly higher adhesion of S. mutans strains Ingbritt and NG8 and Lactococcus lactis expressing AgI/II adhesins (SpaP or PAc compared to gp-340 II and III proteins. In addition, the gp-340 I protein appeared over represented in subjects positive for Db, an allelic acidic PRP variant associated with caries, and subjects positive for both gp-340 I and Db tended to experience more caries than those negative for both proteins. Conclusion Gp-340 I behaves as a caries
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Sulphur dissociation in nuclear emulsion at 3.7 and 200A GeV
Energy Technology Data Exchange (ETDEWEB)
El-Nadi, M.; Abdelsalam, A.; Shaat, E.A.; Abou Moussa, Z. [Physics Department, Faculty of Science, Cairo University, Giza (Egypt); Hussien, A. [Physics Department, Faculty of Science, Cairo University, Fayoum Branch, Fayoum (Egypt); Ali-Mossa, N. [Basic Science Department, Faculty of Engineering, Banha Branch, Zagazig University, Banha (Egypt); Kamel, S.; Hafiz, M.E. [Physics Department, Faculty of Education, Ain Shams University, Cairo (Egypt); Abdel-Waged, K.H. [Physics Department, Faculty of Science, Zagazig University, Banha (Egypt)
2002-02-01
In this work, the electromagnetic dissociation (EMD) of sulphur projectile induced by two widely differing energies in nuclear emulsions is investigated. Although the percentages of EMD events of the total numbers of studied interactions are relatively small, i.e. 5.7 and 14.4% for 3.7 and 200A GeV interactions respectively, one could extract some results out of them. The emission of a proton through the {sup 32}S({gamma}, p){sup 31}P channel is found to be a dominant process (43.8%) at 200A GeV whereas the single alpha emission through the {sup 32}S({gamma}, {alpha}){sup 28}Si channel is the dominant one (34.0%) at 3.7A GeV. Multiplicity distributions of hydrogen and helium isotopes as well as the measured probabilities for the different modes of fragmentation are studied. The comparison of the present results, from electromagnetic and peripheral nuclear interactions, indicates the effective role of the different reaction mechanisms at ultra-relativistic energy (200A GeV). The experimental inclusive cross sections of different fragmentation modes produced in the EMD of {sup 32}S ions at 200A GeV were found to be in satisfactory agreement with the predictions of the combined approach of Pshenichnov et al. (author)
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46 CFR 178.340 - Stability standards for pontoon vessels on protected waters.
2010-10-01
... 46 Shipping 7 2010-10-01 2010-10-01 false Stability standards for pontoon vessels on protected waters. 178.340 Section 178.340 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL....340 Stability standards for pontoon vessels on protected waters. (a) The portion of the deck...
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10 CFR 600.340 - Purpose of reports and records.
2010-01-01
... and reporting financial and program performance and for records retention. ... 10 Energy 4 2010-01-01 2010-01-01 false Purpose of reports and records. 600.340 Section 600.340 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Administrative...
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EAS experiment on board the Airbus A380
International Nuclear Information System (INIS)
Capdevielle, J.N.; Cohen, F.; Jedrzejczak, K.; Szabelska, B.; Szabelski, J.; Wibig, T.
2006-01-01
We consider taking the opportunity of about 10,000 hours of test flights of the Airbus A380, and to install in the passenger area detectors for high energy cosmic ray events. The altitude of 10 km (250 g/cm 2 ) presents the opportunity to measure EAS originating from heavy primaries to energies exceeding 10 7 GeV, and also the proton component beyond the energy of the knee arriving without interaction. At the flight altitude iron originated EAS are well developed and by registering their lateral distribution in the 70 meters long cabin it will be possible to distinguish them from proton originated EAS. The hadron component of EAS (registered as number of secondary hadrons produced in the detector) would help in discrimination and energy estimation. On the other hand, the detection of high energy protons (without EAS) would enable us to measure the high energy proton spectrum. The proton energy would be estimated via hadron multiplicity in single interactions inside the detector. We propose to use about 60 modules of 0.5 m 2 of active detectors with scintillators to detect E-M component and a carbon target with lead layer to detect the hadronic component via neutron registrations
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40 CFR 415.340 - Applicability; description of the chrome pigments production subcategory.
2010-07-01
... chrome pigments production subcategory. 415.340 Section 415.340 Protection of Environment ENVIRONMENTAL... SOURCE CATEGORY Chrome Pigments Production Subcategory § 415.340 Applicability; description of the chrome pigments production subcategory. This subpart applies to discharges to waters of the United States and...
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CSER 94-012: Criticality safety evaluation report for 340 Facility
International Nuclear Information System (INIS)
Altschuler, S.J.
1995-01-01
This Criticality Safety Evaluation Report (CSER) covers the 340 Facility which acts as a collecting point for liquid and solid waste from various facilities in the 300 Area. Criticality safety is achieved by controlling the amount and concentration of the fissionable material sent to the 340 Facility from the originating facilities in the 300 Area, a method similar to that used elsewhere at Hanford for the waste tank farms. Unlike those, however, the waste received at the 340 Facility will be far less radioactive. It is concluded that present operations meet the two contingency criterion. The facility will still be safely subcritical even after two independent and concurrent failures (either of equipment or administrative controls). The solid waste storage and liquid waste will be managed separately. The solid waste storage area is classified as exempt because it contains less than 15 grams of fissionable materials. The Radioactive Liquid Waste System is classified as isolated because it contains less than one third of a minimum critical mass. The criticality safety of the 340 Facility devoted to the Radioactive Liquid Waste System (RLWS) is assured by the form and concentration of the fissile material and could also be classified as a limited control facility. However, the 340 Facility has been operated as an isolated facility which results in a more conservative limit
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Placental miR-340 mediates vulnerability to activity based anorexia in mice.
Schroeder, Mariana; Jakovcevski, Mira; Polacheck, Tamar; Drori, Yonat; Luoni, Alessia; Röh, Simone; Zaugg, Jonas; Ben-Dor, Shifra; Albrecht, Christiane; Chen, Alon
2018-04-23
Anorexia nervosa (AN) is a devastating eating disorder characterized by self-starvation that mainly affects women. Its etiology is unknown, which impedes successful treatment options leading to a limited chance of full recovery. Here, we show that gestation is a vulnerable window that can influence the predisposition to AN. By screening placental microRNA expression of naive and prenatally stressed (PNS) fetuses and assessing vulnerability to activity-based anorexia (ABA), we identify miR-340 as a sexually dimorphic regulator involved in prenatal programming of ABA. PNS caused gene-body hypermethylation of placental miR-340, which is associated with reduced miR-340 expression and increased protein levels of several target transcripts, GR, Cry2 and H3F3b. MiR-340 is linked to the expression of several nutrient transporters both in mice and human placentas. Using placenta-specific lentiviral transgenes and embryo transfer, we demonstrate the key role miR-340 plays in the mechanism involved in early life programming of ABA.
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2013-05-03
..., manual fire-fighting system, oxygen system and occupant amenities are provided. Additionally, a sink and... developed to assure that a crew member entering the LDCR compartment through the vestibule to fight a fire... and fire suppression systems (including airflow management features which prevent hazardous quantities...
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Energy transition. Who will board the energy Airbus?
International Nuclear Information System (INIS)
Moragues, Manuel
2014-01-01
As the French President called for the creation of a French-German company dedicated to energy transition, inspired by the Airbus project which emerged to share the design and development costs of a specific product (a large capacity aircraft), this article comments the possibility of applying such a strategy between the main French and German actors like Siemens, RWE, Alstom, EDF. Such an idea has already its reality as some French and German are cooperating in different projects: offshore wind energy consortium, research and development in photovoltaic, smart grids, energy storage, and so on. Some of these projects are evoked and commented, for example one which has emerged just after the President's speech: the project of a giant factory of solar arrays proposed by the CEA and the Fraunhofer Institute. One major need is also evoked, the harmonization at the regulation stage
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Clark, Bobby L; Hou, John; Chou, Chia-Hung; Huang, Elbert S; Conti, Rena
2014-11-01
Section 340B of the Public Health Service Act provides qualified organizations serving vulnerable populations with deep discounts for some outpatient medications. A 2010 regulatory change widely expanded the 340B program's reach, allowing these organizations to contract with retail pharmacies to dispense medications for eligible patients. Little is known about which medications are dispensed by contract pharmacies under the expanded program. We provide the first comparison of 340B prescriptions and all prescriptions dispensed in contract pharmacies. We used 2012 data from Walgreens, the national leader in 340B contract pharmacies. Medications used to treat chronic conditions such as diabetes, high cholesterol levels, asthma, and depression accounted for an overwhelming majority of all prescriptions dispensed at Walgreens as part of the 340B program. A higher percentage of antiretrovirals used to treat HIV/AIDS were dispensed through 340B prescriptions than through all prescriptions dispensed at Walgreens. The majority of 340B prescriptions dispensed at Walgreens originated at tuberculosis clinics, consolidated health centers, disproportionate-share hospitals, and Ryan White clinics. Our results suggest that 340B contract pharmacies dispense medications used to treat Americans' chronic disease burden and disproportionately dispense medications used by key vulnerable populations targeted by the program. Project HOPE—The People-to-People Health Foundation, Inc.
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5 CFR 340.203 - Technical assistance.
2010-01-01
... part-time employment practices; (3) Development of special recruitment and selection techniques for...-TIME CAREER EMPLOYMENT (PART-TIME, SEASONAL, ON-CALL, AND INTERMITTENT) Regulatory Requirements-Part-Time Employment § 340.203 Technical assistance. (a) The Office of Personnel Management shall provide...
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13 CFR 130.340 - SBDC services and restrictions on service.
2010-01-01
..., Training and Specialized Services, concerning the formation, financing, management and operation of small... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false SBDC services and restrictions on service. 130.340 Section 130.340 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL...
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Yang, Xiaolan; Hu, Xiaolei; Xu, Bangtian; Wang, Xin; Qin, Jialin; He, Chenxiong; Xie, Yanling; Li, Yuanli; Liu, Lin; Liao, Fei
2014-06-17
A fluorometric titration approach was proposed for the calibration of the quantity of monoclonal antibody (mcAb) via the quench of fluorescence of tryptophan residues. It applied to purified mcAbs recognizing tryptophan-deficient epitopes, haptens nonfluorescent at 340 nm under the excitation at 280 nm, or fluorescent haptens bearing excitation valleys nearby 280 nm and excitation peaks nearby 340 nm to serve as Förster-resonance-energy-transfer (FRET) acceptors of tryptophan. Titration probes were epitopes/haptens themselves or conjugates of nonfluorescent haptens or tryptophan-deficient epitopes with FRET acceptors of tryptophan. Under the excitation at 280 nm, titration curves were recorded as fluorescence specific for the FRET acceptors or for mcAbs at 340 nm. To quantify the binding site of a mcAb, a universal model considering both static and dynamic quench by either type of probes was proposed for fitting to the titration curve. This was easy for fitting to fluorescence specific for the FRET acceptors but encountered nonconvergence for fitting to fluorescence of mcAbs at 340 nm. As a solution, (a) the maximum of the absolute values of first-order derivatives of a titration curve as fluorescence at 340 nm was estimated from the best-fit model for a probe level of zero, and (b) molar quantity of the binding site of the mcAb was estimated via consecutive fitting to the same titration curve by utilizing such a maximum as an approximate of the slope for linear response of fluorescence at 340 nm to quantities of the mcAb. This fluorometric titration approach was proved effective with one mcAb for six-histidine and another for penicillin G.
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21 CFR 558.340 - Maduramicin ammonium.
2010-04-01
.... Feed continuously as sole ration. Do not feed to laying hens. Withdraw 5 days before slaughter. (2... DRUGS, FEEDS, AND RELATED PRODUCTS NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS Specific New Animal Drugs for Use in Animal Feeds § 558.340 Maduramicin ammonium. (a) Approvals. Type A medicated articles: 4.54...
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340 Facility emergency preparedness hazards assessment
International Nuclear Information System (INIS)
Campbell, L.R.
1998-01-01
This document establishes the technical basis in support of Emergency Planning activities for the 340 Facility on the Hanford Site. Through this document, the technical basis for the development of facility specific Emergency Action Levels and Emergency Planning Zone, is demonstrated
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An Airbus arrives at KSC with third MPLM
2001-01-01
An Airbus '''Beluga''' air cargo plane, The Super Transporter, arrives at KSC's Shuttle Landing Facility from the factory of Alenia Aerospazio in Turin, Italy. Its cargo is the Italian Space Agency's Multi-Purpose Logistics Module Donatello, the third of three for the International Space Station. The module will be transported to the Space Station Processing Facility for processing. Among the activities for the payload test team are integrated electrical tests with other Station elements in the SSPF, leak tests, electrical and software compatibility tests with the Space Shuttle (using the Cargo Integrated Test equipment) and an Interface Verification Test once the module is installed in the Space Shuttle's payload bay at the launch pad. The most significant mechanical task to be performed on Donatello in the SSPF is the installation and outfitting of the racks for carrying the various experiments and cargo.
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microRNA-340 induces apoptosis by downregulation of BAG3 in ovarian cancer SKOV3 cells.
Qu, Fei; Wang, Xiufen
2017-08-01
Aberrant expression of miR-340 has been found in several kinds of cancers including ovarian cancer. Pro-apoptotic and anti-metastasis roles of miR-340 in ovarian cancer have also been reported; however, the underling molecular mechanisms by which miR-340 suppresses ovarian cancer are still unclear. This study focused on the role and molecular mechanism of miR-340 in ovarian cancer. Human ovarian carcinoma SKOV3 cells were used and transfected with miR-340 mimic, miR-340 inhibitor and their correspondingly negative controls (mimic control and inhibitor control). Thereafter, cell viability, apoptosis, and the expressions of apoptosis-associated factors and BAG3 were respectively assessed by MTT assay, flow cytometry, qRT-PCR and Western blotting. SKOV3 cells were then co-transfected with miR-340 inhibitor and BAG3 targeted siRNA, then cell viability, apoptosis and the expression of apoptosis-associated factors were retested. Besides, the expressions of main factors in PI3K/AKT pathway were detected. Overexpression of miR-340 suppressed BAG3 cells viability (P BAG3 was negatively regulated by miR-340 (P BAG3 silence significantly induced cell apoptosis (P BAG3 silence abolished miR-340 suppression-induced activation of PI3K and AKT. This study revealed the tumor suppressive role of miR-340 in SKOV3 cells by negative regulation of BAG3. PI3K/AKT pathway might be involved in the regulation of miR-340 and BAG3.
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VLITE Surveys the Sky: A 340 MHz Companion to the VLA Sky Survey (VLASS)
Peters, Wendy; Clarke, Tracy; Brisken, Walter; Cotton, William; Richards, Emily E.; Giacintucci, Simona; Kassim, Namir
2018-01-01
The VLA Low Band Ionosphere and Transient Experiment (VLITE; ) is a commensal observing system on the Karl G. Janksy Very Large Array (VLA) which was developed by the Naval Research Laboratory and NRAO. A 64 MHz sub-band from the prime focus 240-470 MHz dipoles is correlated during nearly all regular VLA observations. VLITE uses dedicated samplers and fibers, as well as a custom designed, real-time DiFX software correlator, and requires no additional resources from the VLA system running the primary science program. The experiment has been operating since November 2014 with 10 antennas; a recent expansion in summer 2017 increased that number to 16 and more than doubled the number of baselines.The VLA Sky Survey (VLASS; ), is an ongoing survey of the entire sky visible to the VLA at a frequency of 2-4 GHz. The observations are made using an "on-the-fly" (OTF) continuous RA scanning technique which fills in the sky by observing along rows of constant declination. VLITE breaks the data into 2-second integrations and correlates these at a central position every 1.5 degrees. All data for each correlator position is imaged separately, corrected and weighted by an appropriately elongated primary beam model, and then combined in the image plane to create a mosaic of the sky. A catalog of the sources is extracted to provide a 340 MHz sky model.We present preliminary images and catalogs from the 2017 VLASS observations which began in early September, 2017, and continued on a nearly daily basis throughout the fall. In addition to providing a unique sky model at 340 MHz, these data complement VLASS by providing spectral indices for all cataloged sources.
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Energy Technology Data Exchange (ETDEWEB)
Vogel, C.; Drubay, B. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. de Mecanique et de Technologie; Cailletaud, G. [Ecole Nationale Superieure des Mines, 75 - Paris (France); Mottot, M. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Direction des Technologies Avancees
1994-12-31
A damage model for anticipating zirconium {alpha} test-piece rupture under cyclic solicitations at 200 degree Celsius is presented. The article is divided into three parts : an experimental approach, the damage model presentation and the application of this model. (O.L.). 10 refs., 7 figs., 4 tabs.
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20 CFR 340.16 - Debt collection.
2010-04-01
... RECOVERY OF BENEFITS § 340.16 Debt collection. (a) The Associate Executive Director for Unemployment and... person paying remuneration for time lost or any sum or damages for personal injury to remit the amount of reimbursement due the Board, if any, within 30 days of the date of the payment of remuneration or damages to an...
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13 CFR 108.340 - Evaluation and selection-general.
2010-01-01
... VENTURE CAPITAL (âNMVCâ) PROGRAM Evaluation and Selection of NMVC Companies § 108.340 Evaluation and... Applicants in such a way as to promote Developmental Venture Capital investments nationwide and in both urban...
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340 nm pulsed UV LED system for europium-based time-resolved fluorescence detection of immunoassays
DEFF Research Database (Denmark)
Rodenko, Olga; Fodgaard, Henrik; Tidemand-Lichtenberg, Peter
2016-01-01
We report on the design, development and investigation of an optical system based on UV light emitting diode (LED) excitation at 340 nm for time-resolved fluorescence detection of immunoassays. The system was tested to measure cardiac marker Troponin I with a concentration of 200 ng....../L in immunoassay. The signal-to-noise ratio was comparable to state-of-the-art Xenon flash lamp based unit with equal excitation energy and without overdriving the LED. We performed a comparative study of the flash lamp and the LED based system and discussed temporal, spatial, and spectral features of the LED...... excitation for time-resolved fluorimetry. Optimization of the suggested key parameters of the LED promises significant increase of the signal-to-noise ratio and hence of the sensitivity of immunoassay systems....
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340 nm pulsed UV LED system for europium-based time-resolved fluorescence detection of immunoassays.
Rodenko, Olga; Fodgaard, Henrik; Tidemand-Lichtenberg, Peter; Petersen, Paul Michael; Pedersen, Christian
2016-09-19
We report on the design, development and investigation of an optical system based on UV light emitting diode (LED) excitation at 340 nm for time-resolved fluorescence detection of immunoassays. The system was tested to measure cardiac marker Troponin I with a concentration of 200 ng/L in immunoassay. The signal-to-noise ratio was comparable to state-of-the-art Xenon flash lamp based unit with equal excitation energy and without overdriving the LED. We performed a comparative study of the flash lamp and the LED based system and discussed temporal, spatial, and spectral features of the LED excitation for time-resolved fluorimetry. Optimization of the suggested key parameters of the LED promises significant increase of the signal-to-noise ratio and hence of the sensitivity of immunoassay systems.
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49 CFR 173.340 - Tear gas devices.
2010-10-01
... SHIPMENTS AND PACKAGINGS Gases; Preparation and Packaging § 173.340 Tear gas devices. (a) Packagings for...) Tear gas devices may not be assembled with, or packed in the same packaging with, mechanically- or manually-operated firing, igniting, bursting, or other functioning elements unless of a type and design...
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Comprehensive Legislative Reform to Protect the Integrity of the 340B Drug Discount Program.
Zeta, Lowell M
2015-01-01
The 40B Drug Discount Program (340B Program) is a federally facilitated program that requires drug manufacturers to provide steep discounts on outpatient prescription drugs to qualifying safety net health care providers. The federal program is intended as a safeguard to ensure access to affordable drugs to the indigeut. However, over the last two decades safety net health care providers have exploited financial incentives under the 340B Program at the expense of drug manufacturers and patients, including the most needy and vulnerable populations-they are committed to serve. Although the federal government has been applauded for increasing effortsto combat health care fraud and abuse including recovering $3.3 billion in 2014, federal officials and the general public have paid markedly less attention to pervasive abuse of the 340B Program. In 2014, drug purchases of 340B-designated drugs totaled $7 billion and are expected to increase to $12 billion: by 2016 as a result of the expansion of the program under the Affordable Care Act. The 340B Program has completely lost its way, and comprehensive legislation is necessary to realign the program with its intent.
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40 CFR 161.340 - Toxicology data requirements.
2010-07-01
... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Toxicology data requirements. 161.340... Toxicology data requirements. (a) Table. Sections 161.100 through 161.102 describe how to use this table to determine the toxicology data requirements and the substance to be tested. Kind of data required (b) Notes...
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7 CFR 1210.340 - Budget and expenses.
2010-01-01
...) The Board is authorized to incur such expenses for research, development, advertising, or promotion of... PROMOTION PLAN Watermelon Research and Promotion Plan Expenses and Assessments § 1210.340 Budget and... disbursements in the administration of this Plan, including probable costs of research, development, advertising...
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Phenotype abnormality: 340 [Arabidopsis Phenome Database[Archive
Lifescience Database Archive (English)
Full Text Available 340 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u1ria224u845i increased number of lateral root... in organ named primary root ... primary root ... present in greater numbers in organism ... lateral root ...
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Erata, Ferhat; Gardent, Claire; Gyawali, Bikash; Shimorina, Anastasia; Lussaud, Yvan; Tekinerdogan, Bedir; Kardas, Geylani; Monceaux, Anne
2017-01-01
The ModelWriter platform provides a generic framework for automated traceability analysis. In this paper, we demonstrate how this framework can be used to trace the consistency and completeness of technical documents that consist of a set of System Installation Design Principles used by Airbus to
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Solubility of 3-Caffeoylquinic Acid in Different Solvents at 291-340 K
Wang, Y. T.; Zhang, C. L.; Cheng, X. L.; Zhao, J. H.; Wang, L. C.
2017-12-01
Using a laser monitoring observation technique the solubilities of 3-caffeoylquinic acid in pure solvents, water, methanol, ethanol, 1-propanol, 1-butanol, and two mixed solvents, methanol + water, ethanol + water have been determined at temperature range from 291-340 K. The experimental data were correlated by the modified Apelblat equation, λ h equation, and ideal model. The calculated solubilities were turned out very consistent with the experimental results, and the modified Apelblat equation shows the best agreement.
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Directory of Open Access Journals (Sweden)
Phillipe Nédélec
2015-06-01
Full Text Available This article presents the In-service Aircraft of a Global Observing System (IAGOS developed for operations on commercial long-range Airbus aircraft (A330/A340 for monitoring the atmospheric composition. IAGOS is the continuation of the former Measurement of OZone and water vapour on Airbus In-service airCraft (MOZAIC programme (1994–2014 with five aircraft operated by European airlines over 20 yr. MOZAIC has provided unique scientific database used worldwide by the scientific community. In continuation of MOZAIC, IAGOS aims to equip a fleet up to 20 aircraft around the world and for operations over decades. IAGOS started in July 2011 with the first instruments installed aboard a Lufthansa A340-300, and a total of six aircraft are already in operation. We present the technical aircraft system concept, with basic instruments for O3, CO, water vapour and clouds; and optional instruments for measuring either NOy, NOx, aerosols or CO2/CH4. In this article, we focus on the O3 and CO instrumentation while other measurements are or will be described in specific papers. O3 and CO are measured by optimised but well-known methods such as UV absorption and IR correlation, respectively. We describe the data processing/validation and the data quality control for O3 and CO. Using the first two overlapping years of MOZAIC/IAGOS, we conclude that IAGOS can be considered as the continuation of MOZAIC with the same data quality of O3 and CO measurements.
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Dynamic model for the control system simulation and design of a 200 MW nuclear heating reactor
International Nuclear Information System (INIS)
Zhang Yuai; Liu Longzhi; Ma Changwen
1999-01-01
The author develops a nonlinear dynamic model used in a wide range control system simulation for a 200 MW Nuclear Heating Reactor (NHR-200). Besides a one-point neutron kinetics equation and temperature feedback based on the lumped fuel and coolant temperature, which are the usual methods used in modeling of PWR, two other factors are also considered in order to suit the wide range operation. The first consideration is the natural circulation in the primary loop because it affects the heat transfer coefficients in the core and in the primary heat exchanger (PHE). The second consideration is the flow rate variation in the secondary loop which leads to some nonlinear properties. The simulation results show that the model is accurate enough for control system simulation. Some model reduction basis can be obtained through the dynamic analysis
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miR-340 inhibits glioblastoma cell proliferation by suppressing CDK6, cyclin-D1 and cyclin-D2
International Nuclear Information System (INIS)
Li, Xuesong; Gong, Xuhai; Chen, Jing; Zhang, Jinghui; Sun, Jiahang; Guo, Mian
2015-01-01
Glioblastoma development is often associated with alteration in the activity and expression of cell cycle regulators, such as cyclin-dependent kinases (CKDs) and cyclins, resulting in aberrant cell proliferation. Recent studies have highlighted the pivotal roles of miRNAs in controlling the development and growth of glioblastoma. Here, we provide evidence for a function of miR-340 in the inhibition of glioblastoma cell proliferation. We found that miR-340 is downregulated in human glioblastoma tissue samples and several established glioblastoma cell lines. Proliferation and neurosphere formation assays revealed that miR-340 plays an oncosuppressive role in glioblastoma, and that its ectopic expression causes significant defect in glioblastoma cell growth. Further, using bioinformatics, luciferase assay and western blot, we found that miR-340 specifically targets the 3′UTRs of CDK6, cyclin-D1 and cyclin-D2, leading to the arrest of glioblastoma cells in the G0/G1 cell cycle phase. Confirming these results, we found that re-introducing CDK6, cyclin-D1 or cyclin-D2 expression partially, but significantly, rescues cells from the suppression of cell proliferation and cell cycle arrest mediated by miR-340. Collectively, our results demonstrate that miR-340 plays a tumor-suppressive role in glioblastoma and may be useful as a diagnostic biomarker and/or a therapeutic avenue for glioblastoma. - Highlights: • miR-340 is downregulated in glioblastoma samples and cell lines. • miR-340 inhibits glioblastoma cell proliferation. • miR-340 directly targets CDK6, cyclin-D1, and cyclin-D2. • miR-340 regulates glioblastoma cell proliferation via CDK6, cyclin-D1 and cyclin-D2
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miR-340 inhibits glioblastoma cell proliferation by suppressing CDK6, cyclin-D1 and cyclin-D2
Energy Technology Data Exchange (ETDEWEB)
Li, Xuesong; Gong, Xuhai [Department of Neurology, Daqing Oilfield General Hospital, Daqing, Heilongjiang 163001 (China); Chen, Jing [Department of Neurology, Daqing Longnan Hospital, Daqing, Heilongjiang, 163001 China (China); Zhang, Jinghui [Department of Cardiology, The Fourth Hospital of Harbin City, Harbin, Heilongjiang 150026 (China); Sun, Jiahang [Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086 (China); Guo, Mian, E-mail: guomian_hyd@163.com [Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086 (China)
2015-05-08
Glioblastoma development is often associated with alteration in the activity and expression of cell cycle regulators, such as cyclin-dependent kinases (CKDs) and cyclins, resulting in aberrant cell proliferation. Recent studies have highlighted the pivotal roles of miRNAs in controlling the development and growth of glioblastoma. Here, we provide evidence for a function of miR-340 in the inhibition of glioblastoma cell proliferation. We found that miR-340 is downregulated in human glioblastoma tissue samples and several established glioblastoma cell lines. Proliferation and neurosphere formation assays revealed that miR-340 plays an oncosuppressive role in glioblastoma, and that its ectopic expression causes significant defect in glioblastoma cell growth. Further, using bioinformatics, luciferase assay and western blot, we found that miR-340 specifically targets the 3′UTRs of CDK6, cyclin-D1 and cyclin-D2, leading to the arrest of glioblastoma cells in the G0/G1 cell cycle phase. Confirming these results, we found that re-introducing CDK6, cyclin-D1 or cyclin-D2 expression partially, but significantly, rescues cells from the suppression of cell proliferation and cell cycle arrest mediated by miR-340. Collectively, our results demonstrate that miR-340 plays a tumor-suppressive role in glioblastoma and may be useful as a diagnostic biomarker and/or a therapeutic avenue for glioblastoma. - Highlights: • miR-340 is downregulated in glioblastoma samples and cell lines. • miR-340 inhibits glioblastoma cell proliferation. • miR-340 directly targets CDK6, cyclin-D1, and cyclin-D2. • miR-340 regulates glioblastoma cell proliferation via CDK6, cyclin-D1 and cyclin-D2.
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Fatal Prion Disease in a Mouse Model of Genetic E200K Creutzfeldt-Jakob Disease
Friedman-Levi, Yael; Meiner, Zeev; Canello, Tamar; Frid, Kati; Kovacs, Gabor G.; Budka, Herbert; Avrahami, Dana; Gabizon, Ruth
2011-01-01
Genetic prion diseases are late onset fatal neurodegenerative disorders linked to pathogenic mutations in the prion protein-encoding gene, PRNP. The most prevalent of these is the substitution of Glutamate for Lysine at codon 200 (E200K), causing genetic Creutzfeldt-Jakob disease (gCJD) in several clusters, including Jews of Libyan origin. Investigating the pathogenesis of genetic CJD, as well as developing prophylactic treatments for young asymptomatic carriers of this and other PrP mutations, may well depend upon the availability of appropriate animal models in which long term treatments can be evaluated for efficacy and toxicity. Here we present the first effective mouse model for E200KCJD, which expresses chimeric mouse/human (TgMHu2M) E199KPrP on both a null and a wt PrP background, as is the case for heterozygous patients and carriers. Mice from both lines suffered from distinct neurological symptoms as early as 5–6 month of age and deteriorated to death several months thereafter. Histopathological examination of the brain and spinal cord revealed early gliosis and age-related intraneuronal deposition of disease-associated PrP similarly to human E200K gCJD. Concomitantly we detected aggregated, proteinase K resistant, truncated and oxidized PrP forms on immunoblots. Inoculation of brain extracts from TgMHu2ME199K mice readily induced, the first time for any mutant prion transgenic model, a distinct fatal prion disease in wt mice. We believe that these mice may serve as an ideal platform for the investigation of the pathogenesis of genetic prion disease and thus for the monitoring of anti-prion treatments. PMID:22072968
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Fatal prion disease in a mouse model of genetic E200K Creutzfeldt-Jakob disease.
Directory of Open Access Journals (Sweden)
Yael Friedman-Levi
2011-11-01
Full Text Available Genetic prion diseases are late onset fatal neurodegenerative disorders linked to pathogenic mutations in the prion protein-encoding gene, PRNP. The most prevalent of these is the substitution of Glutamate for Lysine at codon 200 (E200K, causing genetic Creutzfeldt-Jakob disease (gCJD in several clusters, including Jews of Libyan origin. Investigating the pathogenesis of genetic CJD, as well as developing prophylactic treatments for young asymptomatic carriers of this and other PrP mutations, may well depend upon the availability of appropriate animal models in which long term treatments can be evaluated for efficacy and toxicity. Here we present the first effective mouse model for E200KCJD, which expresses chimeric mouse/human (TgMHu2M E199KPrP on both a null and a wt PrP background, as is the case for heterozygous patients and carriers. Mice from both lines suffered from distinct neurological symptoms as early as 5-6 month of age and deteriorated to death several months thereafter. Histopathological examination of the brain and spinal cord revealed early gliosis and age-related intraneuronal deposition of disease-associated PrP similarly to human E200K gCJD. Concomitantly we detected aggregated, proteinase K resistant, truncated and oxidized PrP forms on immunoblots. Inoculation of brain extracts from TgMHu2ME199K mice readily induced, the first time for any mutant prion transgenic model, a distinct fatal prion disease in wt mice. We believe that these mice may serve as an ideal platform for the investigation of the pathogenesis of genetic prion disease and thus for the monitoring of anti-prion treatments.
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2011-05-11
..., 2008. (A) If cracking is found and the radius of the rework is less than 20.0 mm (0.787 inch), before... paragraph (g)(6) of this AD. (B) If cracking is found and the radius of the rework is 20.0 mm (0.787 inch... information do not specify a corrective action if cracking is found and the radius of the rework is 20.0 mm (0...
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340 Waste handling Facility Hazard Categorization and Safety Analysis
International Nuclear Information System (INIS)
Rodovsky, T.J.
2010-01-01
The analysis presented in this document provides the basis for categorizing the facility as less than Hazard Category 3. The final hazard categorization for the deactivated 340 Waste Handling Facility (340 Facility) is presented in this document. This hazard categorization was prepared in accordance with DOE-STD-1 027-92, Change Notice 1, Hazard Categorization and Accident Analysis Techniques for Compliance with Doe Order 5480.23, Nuclear Safety Analysis Reports. The analysis presented in this document provides the basis for categorizing the facility as less than Hazard Category (HC) 3. Routine nuclear waste receiving, storage, handling, and shipping operations at the 340 Facility have been deactivated, however, the facility contains a small amount of radioactive liquid and/or dry saltcake in two underground vault tanks. A seismic event and hydrogen deflagration were selected as bounding accidents. The generation of hydrogen in the vault tanks without active ventilation was determined to achieve a steady state volume of 0.33%, which is significantly less than the lower flammability limit of 4%. Therefore, a hydrogen deflagration is not possible in these tanks. The unmitigated release from a seismic event was used to categorize the facility consistent with the process defined in Nuclear Safety Technical Position (NSTP) 2002-2. The final sum-of-fractions calculation concluded that the facility is less than HC 3. The analysis did not identify any required engineered controls or design features. The Administrative Controls that were derived from the analysis are: (1) radiological inventory control, (2) facility change control, and (3) Safety Management Programs (SMPs). The facility configuration and radiological inventory shall be controlled to ensure that the assumptions in the analysis remain valid. The facility commitment to SMPs protects the integrity of the facility and environment by ensuring training, emergency response, and radiation protection. The full scale
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Implementation of GENSEC section from HYDRA 3.40 system on IBM 370/135 (DOS/VS 34.0)
International Nuclear Information System (INIS)
Ponta, T.
1984-07-01
In High Energy Physics, processing and interpretation of experimental data, supplied by track-particle detectors, are made by means of HYDRA system. We present here the implementation on IBM 370/135 (DOS/VS 34.0) (belonqing to Central Institute of Physics) of General Section (GENSEC) from HYDRA system, paying a special attention to the description of the 176 routines of this section, in order to facilitate their use on the computer. (author)
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Structural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40 in Aqueous Trifluoroethanol.
Directory of Open Access Journals (Sweden)
Christina Dammers
Full Text Available A hallmark of Alzheimer's disease (AD is the accumulation of extracellular amyloid-β (Aβ plaques in the brains of patients. N-terminally truncated pyroglutamate-modified Aβ (pEAβ has been described as a major compound of Aβ species in senile plaques. pEAβ is more resistant to degradation, shows higher toxicity and has increased aggregation propensity and β-sheet stabilization compared to non-modified Aβ. Here we characterized recombinant pEAβ(3-40 in aqueous trifluoroethanol (TFE solution regarding its aggregation propensity and structural changes in comparison to its non-pyroglutamate-modified variant Aβ(1-40. Secondary structure analysis by circular dichroism spectroscopy suggests that pEAβ(3-40 shows an increased tendency to form β-sheet-rich structures in 20% TFE containing solutions where Aβ(1-40 forms α-helices. Aggregation kinetics of pEAβ(3-40 in the presence of 20% TFE monitored by thioflavin-T (ThT assay showed a typical sigmoidal aggregation in contrast to Aβ(1-40, which lacks ThT positive structures under the same conditions. Transmission electron microscopy confirms that pEAβ(3-40 aggregated to large fibrils and high molecular weight aggregates in spite of the presence of the helix stabilizing co-solvent TFE. High resolution NMR spectroscopy of recombinantly produced and uniformly isotope labeled [U-15N]-pEAβ(3-40 in TFE containing solutions indicates that the pyroglutamate formation affects significantly the N-terminal region, which in turn leads to decreased monomer stability and increased aggregation propensity.
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Achieving high value care for all and the perverse incentives of 340B price agreements.
Whittington, Melanie D; Campbell, Jonathan D; McQueen, R Brett
2018-04-01
Section 340B of the Public Health Service Act requires drug manufacturers to enter into price agreements with the Department of Health and Human Services. These agreements result in variation in the price paid to acquire a drug by sector, which complicates the price used in cost-effectiveness analyses. We describe the transactions and sectors in a 340B agreement using a multiple sclerosis drug. Cost-effectiveness estimates were calculated for the drug using drug prices from the manufacturer and payer perspective. We found the amount paid to the manufacturer (340B price) was a good value ($118,256 per quality-adjusted life-year); however, from the payer drug cost perspective, good value ($196,683 per quality-adjusted life-year) was not achieved. Given that emerging value frameworks incorporate cost-effectiveness, these price variations may have downstream negative consequences, including inaccurate coverage and reimbursement policy recommendations. Upcoming policy changes to the 340B program should incentivize pricing schemes hinged on transparency and value.
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Project W-340 tank 241-C-106 manipulator system closeout summary
International Nuclear Information System (INIS)
McDaniel, L.B.
1995-02-01
This document summarizes the work that was ongoing when Project W-340 was put on hold. Project W-340: Tank 241-C-106 Manipulator Retrieval System, was a candidate FY98 Major System Acquisition. The project was to develop, procure and deploy a Long Reach Manipulator (LRM) waste retrieval system to provide an alternate method to completing the in-tank demonstration of Single Shell Tank waste retrieval technology. The need for enhanced capabilities derives from (1) the inability of the baseline technology to retrieve certain hard waste forms; (2) uncertainty in the quantity of leakage which will be allowed. Numerous studies over the years have identified an arm architecture as a promising retrieval technology to overcome these concerns. The W340 project was intended to further develop and demonstrate this alternative, as part of selecting the best approach for all tanks. Prior to completing the effort, it was determined that an LRM system was too architecture specific and was envisioned to be too expensive for a one time demonstration of retrieval technology. At the time the work was stopped, an effort was underway to broaden the project scope to allow alternatives to an arm-based system
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20 CFR 405.340 - Deciding a claim without a hearing before an administrative law judge.
2010-04-01
....340 Deciding a claim without a hearing before an administrative law judge. (a) Decision wholly... the decision is based. (b) You do not wish to appear. The administrative law judge may decide a claim... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Deciding a claim without a hearing before an...
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Fernando, R; Vanezis, P
1998-06-01
A Thai Airbus, carrying 99 passengers and 14 crew members, traveling from Bangkok to Kathmandu, hit a mountain and crashed several minutes before landing. There were no survivors. Recovered human remains, none of which was easily identifiable, varied in size from a small piece of muscle to mutilated bodies. Of the 97 fragments, only 15 were sufficiently intact (albeit, only partially) to be designated as "bodies." Of the fragments and "bodies," only 11 were positively identified. Causes of death, although all traumatic, could not be stated accurately due to the degree of disintegration. Identification of human remains in these circumstances is a major problem for the pathologist.
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Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages
Directory of Open Access Journals (Sweden)
Tony Valente
2017-05-01
Full Text Available In the brain of patients with multiple sclerosis, activated microglia/macrophages appear in active lesions and in normal appearing white matter. However, whether they play a beneficial or a detrimental role in the development of the pathology remains a controversial issue. The production of pro-inflammatory molecules by chronically activated microglial cells is suggested to contribute to the progression of neurodegenerative processes in neurological disease. In the healthy brain, neurons control glial activation through several inhibitory mechanisms, such as the CD200-CD200R1 interaction. Therefore, we studied whether alterations in the CD200-CD200R1 system might underlie the neuroinflammation in an experimental autoimmune encephalomyelitis (EAE model of multiple sclerosis. We determined the time course of CD200 and CD200R1 expression in the brain and spinal cord of an EAE mouse model from presymptomatic to late symptomatic stages. We also assessed the correlation with associated glial activation, inflammatory response and EAE severity. Alterations in CD200 and CD200R1 expression were mainly observed in spinal cord regions in the EAE model, mostly a decrease in CD200 and an increase in CD200R1 expression. A decrease in the expression of the mRNA encoding a full CD200 protein was detected before the onset of clinical signs, and remained thereafter. A decrease in CD200 protein expression was observed from the onset of clinical signs. By contrast, CD200R1 expression increased at EAE onset, when a glial reaction associated with the production of pro- and anti-inflammatory markers occurred, and continued to be elevated during the pathology. Moreover, the magnitude of the alterations correlated with severity of the EAE mainly in spinal cord. These results suggest that neuronal-microglial communication through CD200-CD200R1 interaction is compromised in EAE. The early decreases in CD200 expression in EAE suggest that this downregulation might also
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33 CFR 96.340 - Safety Management Certificate: what is it and when is it needed?
2010-07-01
... Safety Management Certificate: what is it and when is it needed? (a) Your U.S. vessel engaged on a... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Safety Management Certificate: what is it and when is it needed? 96.340 Section 96.340 Navigation and Navigable Waters COAST GUARD...
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Nucleon-nucleus optical model up to 200 MeV. Proceedings of a specialist meeting
International Nuclear Information System (INIS)
OECD Nuclear Energy Agency; Commissariat a l'Energie Atomique
1997-01-01
The proceedings of the Specialists Meeting on Nucleon-Nucleus Optical Model up to 200 MeV contains papers on different topics in connection with the nuclear optical potential research. The purpose of the meeting was to reach a common understanding between nuclear theorists, experimentalists and the applied community on the most reliable approaches to predicting nuclear cross-sections in the medium energy region. The discussion centred around such questions as 'What are the better theoretical models today?', and 'What experimental data are required to test the models?'. 23 items are indexed separately for the INIS database. (K.A.)
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2011-01-03
... radius of the rework is less than 20.0 mm (0.787 inch), before further flight, increase the radius and do... this AD. (B) If cracking is found and the radius of the rework is 20.0 mm (0.787 inch) or more, before... cracking is found and the radius of the rework is 20.0 mm (0.787 inch) or more. Paragraph (g)(3)(i)(B) of...
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9 CFR 592.340 - Supervision of marking and packaging.
2010-01-01
... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Supervision of marking and packaging... § 592.340 Supervision of marking and packaging. (a) Evidence of label approval. Inspection program... evidence that such official identification or packaging material bearing such official identification has...
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A Critical Role for CD200R Signaling in Limiting the Growth and Metastasis of CD200+ Melanoma.
Liu, Jin-Qing; Talebian, Fatemeh; Wu, Lisha; Liu, Zhihao; Li, Ming-Song; Wu, Laichu; Zhu, Jianmin; Markowitz, Joseph; Carson, William E; Basu, Sujit; Bai, Xue-Feng
2016-08-15
CD200 is a cell surface glycoprotein that functions through engaging CD200R on cells of the myeloid lineage and inhibits their functions. Expression of CD200 was implicated in a variety of human cancer cells, including melanoma cells; however, its roles in tumor growth and immunity are not clearly understood. In this study, we used CD200R-deficient mice and the B16 tumor model to evaluate this issue. We found that CD200R-deficient mice exhibited accelerated growth of CD200(+), but not CD200(-), B16 tumors. Strikingly, CD200R-deficient mice receiving CD200(+) B16 cells i.v. exhibited massive tumor growth in multiple organs, including liver, lung, kidney, and peritoneal cavity, whereas the growth of the same tumors in wild-type mice was limited. CD200(+) tumors grown in CD200R-deficient mice contained higher numbers of CD11b(+)Ly6C(+) myeloid cells, exhibited increased expression of VEGF and HIF1α genes with increased angiogenesis, and showed significantly reduced infiltration of CD4(+) and CD8(+) T cells, presumably as the result of reduced expression of T cell chemokines, such as CXCL9 and CXCL16. The liver from CD200R-deficient mice, under metastatic growth of CD200(+) tumors, contained significantly increased numbers of CD11b(+)Gr1(-) myeloid cells and Foxp3(+) regulatory T cells and reduced numbers of NK cells. Liver T cells also had a reduced capacity to produce IFN-γ or TNF-α. Taken together, we revealed a critical role for CD200R signaling in limiting the growth and metastasis of CD200(+) tumors. Thus, targeting CD200R signaling may potentially interfere with the metastatic growth of CD200(+) tumors, like melanoma. Copyright © 2016 by The American Association of Immunologists, Inc.
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Managing path-breaking innovations CERN-ATLAS, Airbus, and stem cell research
Liyanage, Shanta; Nordberg, Markus
2007-01-01
Path-breaking innovations are about instigating fundamental changes in people, organizations, communities, and economies. They are complex, continuous, and evolutionary processes that take considerable time, resources, and the efforts of many individuals and organizations to be accomplished successfully. Representing distinct departures from existing practices, they differ from other types of innovation, such as product extensions and incremental improvements. By examining path-breaking innovation processes through in-depth analysis of several large-scale initiatives around the world, the authors explore how profound changes in product, process, and service can be explained and managed, and consider the practical implications for scientific, organizational, institutional, and political leaders concerned with channeling innovation toward economic growth. In-depth analysis of science and technology initiatives at CERN-ATLAS, Airbus, and in stem cell research, the authors explore and illuminate how profound cha...
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Radioactive air emissions notice of construction 340-A building tank sludge clean out
International Nuclear Information System (INIS)
Hays, C.B.
1997-01-01
This document serves as a notice of construction pursuant to the requirements of Washington Administrative Code (WAC) 246-247-060 and as a request for approval to construct pursuant to 40 Code of Federal Regulations (CFR) 61.96 for the removal of sludge from six storage tanks located inside the 340-A Building, which is located in the 300 Area of the Hanford Site
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Wang, Cheng; He, Yue; Lu, Bin; Jiang, Jun; Miao, Li; Deng, Xian-Jin; Xiong, Yong-zhong; Zhang, Jian
2017-11-01
This paper presents a sub-harmonic mixer at 340 GHz based on anti-parallel Schottky diodes (SBDs). Intrinsic resonances in low-pass hammer-head filter have been adopted to enhance the isolation for different harmonic components, while greatly minimizing the transmission loss. The application of new DC grounding structure, impedance matching structure, and suspended micro-strip mitigates the negative influences of fabrication errors from metal cavity, quartz substrate, and micro-assembly. An improved lumped element equivalent circuit model of SBDs guarantees the accuracy of simulation, which takes current-voltage (I/V) behavior, capacitance-voltage (C/V) behavior, carrier velocity saturation, DC series resistor, plasma resonance, skin effect, and four kinds of noise generation mechanisms into consideration thoroughly. The measurement indicates that with local oscillating signal of 2 mW, the lowest double sideband conversion loss is 5.5 dB at 339 GHz; the corresponding DSB noise temperature is 757 K. The 3 dB bandwidth of conversion loss is 50 GHz from 317 to 367 GHz.
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A fully microscopic model of 200 MeV proton-12C elastic and inelastic scattering
International Nuclear Information System (INIS)
Karataglidis, S.; Dortmans, P.J.; Amos, K.; de Swiniarski, R.
1996-01-01
An effective two nucleon (NN) interaction in the nuclear medium is defined from an accurate mapping of the NN g matrices obtained by solving the Brueckner-Bethe-Goldstone equations for infinite nuclear matter. That effective interaction is used in a fully microscopic calculation of the nonlocal effective proton- 12 C interaction from which are obtained predictions of the differential cross section and analysing power for 200 MeV elastic scattering. The relative motion wave functions so found are used as the distorted waves in a distorted wave approximation (DWA) study of select inelastic scattering events. The effective NN interaction is used as the transition operator in those calculations. The relevant nuclear spectroscopy for the elastic and DWA (p, p') calculations is found from a full (0 + 2) ℎω shell model evaluation of the positive parity states while a restricted (1 + 3)ℎω has been used to give the negative parity states. Results are compared with those of the 0p-shell model of Cohen and Kurath or with those based upon axially symmetric, projected Hartree-Fock calculations. The diverse structure model wave functions are assessed by using them in calculations to compare with measured longitudinal, transverse electric and transverse magnetic form factors from electron scattering to many of the excited states of 12 C. Using those models of the structure of 12 C in the completely microscopic model of the elastic and inelastic scattering of 200 MeV protons, good fits have been found to the cross section and analysing power data. 50 refs., 3 tabs., 20 figs
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7 CFR 906.340 - Container, pack, and container marking regulations.
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Container, pack, and container marking regulations... AGRICULTURE ORANGES AND GRAPEFRUIT GROWN IN LOWER RIO GRANDE VALLEY IN TEXAS Container and Pack Requirements § 906.340 Container, pack, and container marking regulations. (a) No handler shall handle any variety of...
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46 CFR 131.340 - Recommended placard for emergency instructions.
2010-10-01
... weathertight door, hatch, and air-port to prevent taking water aboard or further flooding in the vessel. (2) Keep bilges dry to prevent loss of stability from water in bilges. Use power-driven bilge pump, hand... Section 131.340 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS...
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75 FR 22514 - Airworthiness Directives; The Boeing Company Model 747-200B Series Airplanes
2010-04-29
... Administration (FAA), DOT. ACTION: Final rule; request for comments. SUMMARY: We are adopting a new airworthiness... cracking of the fuselage skin lap joints at stringer 6 on the left and right sides from station (STA) 340... repetitive inspections for the modified area. This AD results from reviews done by Boeing, which show that...
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Triaxiality in the even-mass Hg isotopes: A discontinuity at 200Hg
International Nuclear Information System (INIS)
Morrison, I.; Spear, R.H.
1981-01-01
The mass dependence of excitation energies of the 2 + 1 , 2 + 2 , and 4 + 1 states of the even-mass Hg isotopes, and of some related B(E2) values, shows a marked discontinuity at 200 Hg. Analysis of B(E2;0 + 1 →2 + 1 ) values in terms of an extended interacting boson approximation model suggests that this discontinuity is due to a change in the proton and neutron distributions at 200 Hg. Apart from 200 Hg, the data favor γ-soft models rather than the rigid triaxial-rotor model
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Directory of Open Access Journals (Sweden)
Madeline Carpinelli Wallack
2012-01-01
Full Text Available Purpose: The 340B Drug Pricing Program is a federal program designed to reduce the amount that safety net providers spend on outpatient drugs. The Patient Protection and Affordable Health Care Act of 2010 extended eligibility for 340B to critical access hospitals (CAHs for all drugs except those designated as “orphan.” Because this policy is unprecedented, this study quantifies the gross financial impact that this exemption has on a group of CAHs. Methods: Drug spending for 2010 from 18 CAHs in Minnesota and Wisconsin are reviewed to identify the prevalence of orphan drug purchases and to calculate the price differentials between the 340B price and the hospitals’ current cost. Results: The 18 CAHs’ purchases of orphan drugs comprise an average of 44% of the total annual drug budgets, but only 5% of units purchased, thus representing a very high proportion of their expenditures. In the aggregate, the 18 hospitals would have saved $3.1 million ($171,000 average per hospital had purchases of drugs with orphan designations been made at the 340B price. Because CAH claims for Medicare are reimbursed on a cost-basis, the Federal government is losing an opportunity for savings. Conclusion: The high prevalence of orphan drug use and considerable potential for cost reduction through the 340B program demonstrate the loss of benefit to the hospitals, Federal government and the states.
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Modelling of large sodium fires: A coupled experimental and calculational approach
International Nuclear Information System (INIS)
Astegiano, J.C.; Balard, F.; Cartier, L.; De Pascale, C.; Forestier, A.; Merigot, C.; Roubin, P.; Tenchine, D.; Bakouta, N.
1996-01-01
The consequences of large sodium leaks in secondary circuit of Super-Phenix have been studied mainly with the FEUMIX code, on the basis of sodium fire experiments. This paper presents the status of the coupled AIRBUS (water experiment) FEUMIX approach under development in order to strengthen the extrapolation made for the Super-Phenix secondary circuits calculations for large leakage flow. FEUMIX code is a point code based on the concept of a global interfacial area between sodium and air. Mass and heat transfers through this global area is supposed to be similar. Then, global interfacial transfer coefficient Sih is an important parameter of the model. Correlations for the interfacial area are extracted from a large number of sodium tests. For the studies of hypothetical large sodium leak in secondary circuit of Super-Phenix, flow rates of more than 1 t/s have been considered and extrapolation was made from the existing results (maximum flow rate 225 kg/s). In order to strengthen the extrapolation, water test has been contemplated, on the basis of a thermal hydraulic similarity. The principle is to measure the interfacial area of a hot water jet in air, then to transpose the Sih to sodium without combustion, and to use this value in FEUMIX with combustion modelling. AIRBUS test section is a parallelepipedic gastight tank, 106 m 3 (5.7 x 3.7 x 5) internally insulated. Water jet is injected from heated external auxiliary tank into the cell using pressurized air tank and specific valve. The main measurements performed during each test are injected flow rate air pressure water temperature gas temperature A first series of tests were performed in order to qualify the methodology: typical FCA and IGNA sodium fire tests were represented in AIRBUS, and a comparison of the FEUMIX calculation using Sih value deduced from water experiments show satisfactory agreement. A second series of test for large flow rate, corresponding to large sodium leak in secondary circuit of Super
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2010-07-01
... under this subpart and how may I sell these engines again? 1045.340 Section 1045.340 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Testing Production-line Engines § 1045.340 When may EPA...
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Chen, Song; Wang, Chenran; Yeo, Syn; Liang, Chun-Chi; Okamoto, Takako; Sun, Shaogang; Wen, Jian; Guan, Jun-Lin
2016-01-01
Autophagy is an evolutionarily conserved cellular process controlled through a set of essential autophagy genes (Atgs). However, there is increasing evidence that most, if not all, Atgs also possess functions independent of their requirement in canonical autophagy, making it difficult to distinguish the contributions of autophagy-dependent or -independent functions of a particular Atg to various biological processes. To distinguish these functions for FIP200 (FAK family-interacting protein of 200 kDa), an Atg in autophagy induction, we examined FIP200 interaction with its autophagy partner, Atg13. We found that residues 582–585 (LQFL) in FIP200 are required for interaction with Atg13, and mutation of these residues to AAAA (designated the FIP200-4A mutant) abolished its canonical autophagy function in vitro. Furthermore, we created a FIP200-4A mutant knock-in mouse model and found that specifically blocking FIP200 interaction with Atg13 abolishes autophagy in vivo, providing direct support for the essential role of the ULK1/Atg13/FIP200/Atg101 complex in the process beyond previous studies relying on the complete knockout of individual components. Analysis of the new mouse model showed that nonautophagic functions of FIP200 are sufficient to fully support embryogenesis by maintaining a protective role in TNFα-induced apoptosis. However, FIP200-mediated canonical autophagy is required to support neonatal survival and tumor cell growth. These studies provide the first genetic evidence linking an Atg's autophagy and nonautophagic functions to different biological processes in vivo. PMID:27013233
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2010-07-01
... under this subpart and how may I sell these engines again? 1048.340 Section 1048.340 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, LARGE NONROAD SPARK-IGNITION ENGINES Testing Production-line Engines § 1048.340 When may EPA revoke my...
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2012-03-30
... emergency evacuation, which could result in inadequate buoyancy to support the raft's passenger capacity... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2011... approved under TSO TSO-C69b and installed on Model A330-200 and -300 series airplanes, Model A340-200 and...
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Gao, Xue; Yang, Jiaqiang; Xu, Baoyun; Xie, Wen; Wang, Shaoli; Zhang, Youjun; Yang, Fengshan; Wu, Qingjun
2016-03-18
Abamectin has been used to control the diamondback moth, Plutella xylostella (P. xylostella), which is a major agricultural pest that can rapidly develop resistance against insecticides including abamectin. Although cytochrome P450 has been confirmed to play an important role in resistance in P. xylostella, the specific P450 genes associated with the resistance are unclear. The full-length cDNA of the cytochrome P450 gene CYP340W1 was cloned and characterized in the present study. The cDNA assembly yielded a sequence of 1929 bp, containing the open reading frame (ORF) 1491 bp and encodes a 496-amino acid peptide. CYP340W1 was expressed in all P. xylostella developmental stages but its expression level was highest in larvae and especially in the heads of larvae. The expression of CYP340W1 was significantly higher in an abamectin-resistant strain (ABM-R) than in its susceptible counterpart (ABM-S). In addition, expression of CYP340W1 was increased when the ABM-R strain was exposed to abamectin. When injected into third-stage ABM-R larvae, CYP340W1 dsRNA significantly reduced CYP340W1 expression at 6 h and reduced expression by 83% at 12 h. As a consequence of RNAi, the mortality of the injected abamectin-resistant larvae increased after a 48-h exposure to abamectin. The results indicate that the overexpression of CYP340W1 plays an important role in abamectin resistance in P. xylostella.
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340 Facility Secondary Containment and Leak Detection Project W-302 Functional Design Criteria
Energy Technology Data Exchange (ETDEWEB)
Stordeur, R.T.
1995-03-01
This functional design criteria for the upgrade to the 340 radioactive liquid waste storage facility (Project W-302) specifically addresses the secondary containment issues at the current vault facility of the 340 Complex. This vault serves as the terminus for the Radioactive Liquid Waste System (RLWS). Project W-302 is necessary in order to bring this portion of the Complex into full regulatory compliance. The project title, ``340 Facility Secondary Containment and Leak Detection``, illustrates preliminary thoughts of taking corrective action directly upon the existing vault (such as removing the tanks, lining the vault, and replacing tanks). However, based on the conclusion of the engineering study, ``Engineering Study of the 300 Area Process Wastewater Handling System``, WHC-SD-WM-ER-277 (as well as numerous follow-up meetings with cognizant staff), this FDC prescribes a complete replacement of the current tank/vault system. This offers a greater array of tanks, and provides greater operating flexibility and ease of maintenance. This approach also minimizes disruption to RLWS services during ``tie-in``, as compared to the alternative of trying to renovate the old vault. The proposed site is within the current Complex area, and maintains the receipt of RLWS solutions through gravity flow.
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Sarter, N. B.; Woods, D. D.
1997-01-01
Research and operational experience have shown that one of the major problems with pilot-automation interaction is a lack of mode awareness (i.e., the current and future status and behavior of the automation). As a result, pilots sometimes experience so-called automation surprises when the automation takes an unexpected action or fails to behave as anticipated. A lack of mode awareness and automation surprises can he viewed as symptoms of a mismatch between human and machine properties and capabilities. Changes in automation design can therefore he expected to affect the likelihood and nature of problems encountered by pilots. Previous studies have focused exclusively on early generation "glass cockpit" aircraft that were designed based on a similar automation philosophy. To find out whether similar difficulties with maintaining mode awareness are encountered on more advanced aircraft, a corpus of automation surprises was gathered from pilots of the Airbus A-320, an aircraft characterized by high levels of autonomy, authority, and complexity. To understand the underlying reasons for reported breakdowns in human-automation coordination, we also asked pilots about their monitoring strategies and their experiences with and attitude toward the unique design of flight controls on this aircraft.
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40 CFR 86.340-79 - Gasoline-fueled engine dynamometer test run.
2010-07-01
... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Gasoline-fueled engine dynamometer... Emission Regulations for New Gasoline-Fueled and Diesel-Fueled Heavy-Duty Engines; Gaseous Exhaust Test Procedures § 86.340-79 Gasoline-fueled engine dynamometer test run. (a) This section applies to gasoline...
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Interpretation and modeling of a subsurface injection test, 200 East Area, Hanford, Washington
International Nuclear Information System (INIS)
Smoot, J.L.; Lu, A.H.
1994-11-01
A tracer experiment was conducted in 1980 and 1981 in the unsaturated zone in the southeast portion of the Hanford 200 East Area near the Plutonium-Uranium Extraction (PUREX) facility. The field design consisted of a central injection well with 32 monitoring wells within an 8-m radius. Water containing radioactive and other tracers was injected weekly during the experiment. The unique features of the experiment were the documented control of the inputs, the experiment's three-dimensional nature, the in-situ measurement of radioactive tracers, and the use of multiple injections. The spacing of the test wells provided reasonable lag distribution for spatial correlation analysis. Preliminary analyses indicated spatial correlation on the order of 400 to 500 cm in the vertical direction. Previous researchers found that two-dimensional axisymmetric modeling of moisture content generally underpredicts lateral spreading and overpredicts vertical movement of the injected water. Incorporation of anisotropic hydraulic properties resulted in the best model predictions. Three-dimensional modeling incorporated the geologic heterogeneity of discontinuous layers and lenses of sediment apparent in the site geology. Model results were compared statistically with measured experimental data and indicate reasonably good agreement with vertical and lateral field moisture distributions
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A fully microscopic model of 200 MeV proton-{sup 12}C elastic and inelastic scattering
Energy Technology Data Exchange (ETDEWEB)
Karataglidis, S; Dortmans, P J; Amos, K; de Swiniarski, R
1996-03-01
An effective two nucleon (NN) interaction in the nuclear medium is defined from an accurate mapping of the NN g matrices obtained by solving the Brueckner-Bethe-Goldstone equations for infinite nuclear matter. That effective interaction is used in a fully microscopic calculation of the nonlocal effective proton-{sup 12}C interaction from which are obtained predictions of the differential cross section and analysing power for 200 MeV elastic scattering. The relative motion wave functions so found are used as the distorted waves in a distorted wave approximation (DWA) study of select inelastic scattering events. The effective NN interaction is used as the transition operator in those calculations. The relevant nuclear spectroscopy for the elastic and DWA (p, p`) calculations is found from a full (0 + 2) {Dirac_h}{omega} shell model evaluation of the positive parity states while a restricted (1 + 3){Dirac_h}{omega} has been used to give the negative parity states. Results are compared with those of the 0p-shell model of Cohen and Kurath or with those based upon axially symmetric, projected Hartree-Fock calculations. The diverse structure model wave functions are assessed by using them in calculations to compare with measured longitudinal, transverse electric and transverse magnetic form factors from electron scattering to many of the excited states of {sup 12}C. Using those models of the structure of {sup 12}C in the completely microscopic model of the elastic and inelastic scattering of 200 MeV protons, good fits have been found to the cross section and analysing power data. 50 refs., 3 tabs., 20 figs.
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Directory of Open Access Journals (Sweden)
Chao Liu
2015-05-01
Full Text Available This paper presents the design of terahertz 2× and 4× sub-harmonic down-mixers using Schottky Barrier Diodes fabricated in standard 0.13 μm SiGe BiCMOS technology. The 340 GHz sub-harmonic mixers (SHMs are designed based on anti-parallel-diode-pairs (APDPs. With the 2nd and 4th harmonic, local oscillator (LO frequencies of 170 GHz and 85 GHz are used to pump the two 340 GHz SHMs. With LO power of 7 dBm, the 2× SHM exhibits a conversion loss of 34.5–37 dB in the lower band (320–340 GHz and 35.5–41 dB in the upper band (340–360 GHz; with LO power of 9 dBm, the 4× SHM exhibits a conversion loss of 39–43 dB in the lower band (320–340 GHz and 40–48 dB in the upper band (340–360 GHz. The measured input 1-dB conversion gain compression point for the 2× and 4× SHMs are −8 dBm and −10 dBm at 325 GHz, respectively. The simulated LO-IF (intermediate frequency isolation of the 2× SHM is 21.5 dB, and the measured LO-IF isolation of the 4× SHM is 32 dB. The chip areas of the 2× and 4× SHMs are 330 μm × 580 μm and 550 μm × 610 μm, respectively, including the testing pads.
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2013-04-09
... are no seats, at least one means must be provided to cover anticipated turbulence (e.g., sufficient... intervening cargo compartment wall, the following applies: (a) Any wall of the module (container) forming part...
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DEFF Research Database (Denmark)
Ligtenberg, T J; Bikker, F J; Groenink, J
2001-01-01
bound in a similar way to Streptococcus mutans and surfactant protein-D. Histochemically, the distribution of gp-340 in the submandibular salivary glands was identical with the agglutinin distribution, as shown in a previous paper [Takano, Bogert, Malamud, Lally and Hand (1991) Anat. Rec. 230, 307......-318]. We conclude that agglutinin is identical with gp-340, and that this molecule interacts with S. mutans and surfactant protein-D....
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Test Results of a 200 W Class Hall Thruster
Jacobson, David; Jankovsky, Robert S.
1999-01-01
The performance of a 200 W class Hall thruster was evaluated. Performance measurements were taken at power levels between 90 W and 250 W. At the nominal 200 W design point, the measured thrust was 11.3 mN. and the specific impulse was 1170 s excluding cathode flow in the calculation. A laboratory model 3 mm diameter hollow cathode was used for all testing. The engine was operated on laboratory power supplies in addition to a breadboard power processing unit fabricated from commercially available DC to DC converters.
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SUPPLY CHAIN FEATURES OF THE AEROSPACE INDUSTRY PARTICULAR CASE AIRBUS AND BOEING
Directory of Open Access Journals (Sweden)
Daniela MOCENCO
2015-10-01
Full Text Available Aerospace sector is one of the most globalized industries in terms of market structure and production system. Through aircraft development programs aviation industry has introduced new solutions to develop its products. The role of the partners involved in the development programs for the new generation aircraft is becoming increasingly important. Supply chain management has become a key factor for major manufacturers in the industry. The new strategies introduced by the aircraft manufacturers have increased the complexity of the supply process, design and production from the aviation industry. This paper highlights a series of factors regarding the aircraft programs supply chain management. In the first part are described the problems encountered by the manufacturers and airlines during the development of the most recent aircraft launched A350XWB and B787 Dreamliner; the second part focuses on the organizational structure of the supply chain, suppliers role within supply chain and also there are described the effects of the new strategies adopted by Airbus and Boeing in the aircraft development; the last part focuses on the risks and challenges that aviation industry is facing.
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13 CFR 120.340 - What is the Export Working Capital Program?
2010-01-01
... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What is the Export Working Capital... LOANS Special Purpose Loans Export Working Capital Program (ewcp) § 120.340 What is the Export Working Capital Program? Under the EWCP, SBA guarantees short-term working capital loans made by participating...
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2012-02-07
..., and the FAA must issue a finding of regulatory adequacy pursuant to Sec. 611 of Public Law 92-574, the ``Noise Control Act of 1972.'' The FAA issues special conditions, as defined in 14 CFR 11.19, in... novel or unusual design features: The Model LJ-200-1A10 airplane flight deck design incorporates a...
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Permitting plan for Project W-340, Tank 241-C-106 manipulator retrieval arm
International Nuclear Information System (INIS)
Tollefson, K.S.
1995-01-01
This document describes the regulatory requirements and describes alternative strategies for obtaining permits and approvals for Project W-340, Tank 241-C-106 Manipulator Retrieval Arm. A comprehensive review of environmental regulations has indicated that several environmental reviews, permits, and approvals are required before design, construction, and operation of the facility. The environmental reviews, permits, and approvals, as well the regulatory authority potentially applicable to the Project W-340 Long Reach Manipulator Arm include the following: National Environmental Policy Act of 1969 -- US Department of Energy, Headquarters; State Environmental Policy Act of 1971 -- State of Washington Department of Ecology; Air Permitting; Dangerous Waste Permitting; Miscellaneous Reviews/Permits/Approvals. This document describes the environmental reviews, permits, and approval requirements for the project. It provides a summary of permit application data requirements, alternative strategies for permit completion and approval, as well as the estimated probability of success for each alternative strategy
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Эстонская фирма помогает Airbus / Райго Неудорф
Неудорф, Райго
2009-01-01
Info- ja automaatikasüsteemidega tegelev ettevõte IB Krates OÜ teeb koostööd Euroopa lennukitootjaga Airbus, luues lennukite juhtimissüsteemide uut tarkvara. Eestist osaleb koostööprojektis ka Tallinna Tehnikaülikool
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Waste site grouping for 200 Areas soil investigations
International Nuclear Information System (INIS)
1997-01-01
The purpose of this document is to identify logical waste site groups for characterization based on criteria established in the 200 Areas Soil Remediation Strategy (DOE-RL 1996a). Specific objectives of the document include the following: finalize waste site groups based on the approach and preliminary groupings identified in the 200 Areas Soil Remediation Strategy; prioritize the waste site groups based on criteria developed in the 200 Areas Soil Remediation Strategy; select representative site(s) that best represents typical and worse-case conditions for each waste group; develop conceptual models for each waste group. This document will serve as a technical baseline for implementing the 200 Areas Soil Remediation Strategy. The intent of the document is to provide a framework, based on waste site groups, for organizing soil characterization efforts in the 200 Areas and to present initial conceptual models
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Nuclear models to 200 MeV for high-energy data evaluations. Vol.12
International Nuclear Information System (INIS)
Chadwick, M.; Reffo, G.; Dunford, C.L.; Oblozinsky, P.
1998-01-01
The work of the Nuclear Energy Agency's Subgroup 12 is described, which represents a collaborative effort to summarize the current status of nuclear reaction modelling codes and prioritize desired future model improvements. Nuclear reaction modelling codes that use appropriate physics in the energy region up to 200 MeV are the focus of this study, particularly those that have proved useful in nuclear data evaluation work. This study is relevant to developing needs in accelerator-driven technology programs, which require accurate nuclear data to high energies for enhanced radiation transport simulations to guide engineering design. (author)
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2017-05-19
The Health Resources and Services Administration (HRSA) administers section 340B of the Public Health Service Act (PHSA), referred to as the "340B Drug Pricing Program" or the "340B Program." HRSA published a final rule on January 5, 2017, that set forth the calculation of the ceiling price and application of civil monetary penalties. The final rule applied to all drug manufacturers that are required to make their drugs available to covered entities under the 340B Program. In accordance with a January 20, 2017, memorandum from the Assistant to the President and Chief of Staff, entitled "Regulatory Freeze Pending Review," HRSA issued an interim final rule that delayed the effective date of the final rule published in the Federal Register (82 FR 1210, (January 5, 2017)) to May 22, 2017. HHS invited commenters to provide their views on whether a longer delay of the effective date to October 1, 2017, would be more appropriate. After consideration of the comments received on the interim final rule, HHS is delaying the effective date of the January 5, 2017 final rule, to October 1, 2017.
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Measurements on the SPS 200 MHz Travelling Wave Cavity towards an Impedance Model
Roggen, Toon; Caspers, Fritz; Vollinger, Christine; CERN. Geneva. ATS Department
2016-01-01
This note discusses the contribution of the SPS 200 MHz TWC (Travelling Wave Cavity) to the SPS longitudinal impedance model. The measurement method and setup is briefly explained and a comparison with simulations is discussed for both the fundamental pass band (FPB) as well as the Higher Order Modes (HOMs). In addition a number of improvements to the measurement setup are discussed.
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Performance investigation of ground cooling for the airbus A380 in the United Arab Emirates
International Nuclear Information System (INIS)
Aranjo, Brendan Savio; Hughes, Ben Richard; Chaudry, Hassam Nasarullah
2012-01-01
A combination of the United Arab Emirates (UAE) climate and the increased size of the super jumbo, Airbus A380, have exceeded the working capacity for current ground cooling techniques. These are evident when the aircraft is being prepared for flight and when in the hanger under maintenance with internal cabin temperatures reported at above 30 °C. The existing system used, delivers air at 11.6 °C after which the cabin temperature is still at a high temperature of 31 °C and unable to cool down due to the temperature rises caused by climate conditions and heat dissipation from the electronics in the cabin. The CFD based temperature profile results highlighted that a decrease in inlet temperature to −18 °C at a constant pressure and mass flow rate is sufficient to provide efficient cooling to the cabin at 22 °C. Boundary conditions are determined to specify a new effective cooling system and resolve the ground cooling issue. - Highlights: ► Computational Fluid Dynamics (CFD) analysis was carried out on the aircraft cabin. ► Existing system delivers air at 11.6 °C. ► Cabin temperature is still at a high temperature of 31 °C. ► The inlet temperature of the air should be −18 °C using the existing system. ► Air is delivered at 6.5 kg/s, to cool the cabin to a comfortable temperature of 22 °C.
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International Nuclear Information System (INIS)
Fuchi, H.; Hoshino, K.; Miyanishi, M.; Niu, K.; Niwa, K.; Shibuya, H.; Yanagisawa, Y.; Tasaka, S.; Maeda, Y.; Kimura, H.
1981-01-01
Among secondaries of 4323 interactions produced in an emulsion chamber exposed to a 340 GeV/c negative ion beam of CERN-SPS, 4 pairs of charmed particles were detected. The mean lifetime of D 0 (D 0 -bar) and the inclusive production cross-section of a charmed particle pair by 340 GeV/c pions were evaluated as (3.1sub(-1.6)sup(+ 2.0)) x 10 - 13 sec and 44 +- 22 μb. (author)
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Energy Technology Data Exchange (ETDEWEB)
Fuchi, H; Hoshino, K; Miyanishi, M; Niu, K; Niwa, K; Shibuya, H; Yanagisawa, Y [Nagoya Univ. (Japan). Dept. of Physics; Ushida, N [Faculty of Education, Aichi University of Education, Kariya, Aichi (Japan); Tasaka, S [Tokyo Univ., Tanashi (Japan). Inst. for Cosmic Ray Research; Maeda, Y
1981-06-06
Among secondaries of 4323 interactions produced in an emulsion chamber exposed to a 340 GeV/c negative ion beam of CERN-SPS, 4 pairs of charmed particles were detected. The mean lifetime of D/sup 0/(D/sup 0/-bar) and the inclusive production cross-section of a charmed particle pair by 340 GeV/c pions were evaluated as (3.1sub(-1.6)sup(+ 2.0)) x 10/sup -13/ sec and 44 +- 22 ..mu..b.
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Prakobphol, A; Xu, F; Hoang, V M; Larsson, T; Bergstrom, J; Johansson, I; Frängsmyr, L; Holmskov, U; Leffler, H; Nilsson, C; Borén, T; Wright, J R; Strömberg, N; Fisher, S J
2000-12-22
Salivary agglutinin is a high molecular mass component of human saliva that binds Streptococcus mutans, an oral bacterium implicated in dental caries. To study its protein sequence, we isolated the agglutinin from human parotid saliva. After trypsin digestion, a portion was analyzed by matrix-assisted laser/desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS), which gave the molecular mass of 14 unique peptides. The remainder of the digest was subjected to high performance liquid chromatography, and the separated peptides were analyzed by MALDI-TOF/post-source decay; the spectra gave the sequences of five peptides. The molecular mass and peptide sequence information showed that salivary agglutinin peptides were identical to sequences in lung (lavage) gp-340, a member of the scavenger receptor cysteine-rich protein family. Immunoblotting with antibodies that specifically recognized either lung gp-340 or the agglutinin confirmed that the salivary agglutinin was gp-340. Immunoblotting with an antibody specific to the sialyl Le(x) carbohydrate epitope detected expression on the salivary but not the lung glycoprotein, possible evidence of different glycoforms. The salivary agglutinin also interacted with Helicobacter pylori, implicated in gastritis and peptic ulcer disease, Streptococcus agalactiae, implicated in neonatal meningitis, and several oral commensal streptococci. These results identify the salivary agglutinin as gp-340 and suggest it binds bacteria that are important determinants of either the oral ecology or systemic diseases.
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DEFF Research Database (Denmark)
Hartshorn, Kevan L.; Ligtenberg, Antoon; White, Mitchell R.
2006-01-01
We previously found that scavenger receptor cysteine-rich gp-340 (glycoprotein-340), isolated from lung or saliva, directly inhibits human IAVs (influenza A viruses). We now show that salivary gp-340 has broad antiviral activity against human, equine and porcine IAV strains. Although lung...
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Maintenance study for W-340 Waste Retrieval System
International Nuclear Information System (INIS)
Christensen, C.; Conner, C.C.; Sekot, J.P.
1994-05-01
This study was performed to identify attributes and maintainability requirements for the Tank Waste Retrieval System (TWRS). The system will be developed for Westinghouse Hanford Company in Richland, Washington, as an integrated system to perform waste removal in Tank C-106 and, thus, demonstrate technologies for tank remediation that will satisfy requirements of the Tri-Party Agreement. The study examines attributes of the TWRS, scope of maintenance operations required for the TWRS, maintenance requirements, and potential methods of performing maintenance functions. Recommendations are provided for consideration in the development of both the conceptual design and performance specification, which will be used in procuring the W-340 Waste Retrieval System
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Directory of Open Access Journals (Sweden)
Joanne L Attema
Full Text Available The miR-200b~200a~429 gene cluster is a key regulator of EMT and cancer metastasis, however the transcription-based mechanisms controlling its expression during this process are not well understood. We have analyzed the miR-200b~200a~429 locus for epigenetic modifications in breast epithelial and mesenchymal cell lines using chromatin immunoprecipitation assays and DNA methylation analysis. We discovered a novel enhancer located approximately 5.1kb upstream of the miR-200b~200a~429 transcriptional start site. This region was associated with the active enhancer chromatin signature comprising H3K4me1, H3K27ac, RNA polymerase II and CpG dinucleotide hypomethylation. Luciferase reporter assays revealed the upstream enhancer stimulated the transcription of the miR-200b~200a~429 minimal promoter region approximately 27-fold in breast epithelial cells. Furthermore, we found that a region of the enhancer was transcribed, producing a short, GC-rich, mainly nuclear, non-polyadenylated RNA transcript designated miR-200b eRNA. Over-expression of miR-200b eRNA had little effect on miR-200b~200a~429 promoter activity and its production did not correlate with miR-200b~200a~429 gene expression. While additional investigations of miR-200b eRNA function will be necessary, it is possible that miR-200b eRNA may be involved in the regulation of miR-200b~200a~429 gene expression and silencing. Taken together, these findings reveal the presence of a novel enhancer, which contributes to miR-200b~200a~429 transcriptional regulation in epithelial cells.
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75 FR 10272 - Notice Regarding 340B Drug Pricing Program-Contract Pharmacy Services
2010-03-05
... Regarding 340B Drug Pricing Program--Contract Pharmacy Services AGENCY: Health Resources and Services... drug pricing program by which manufacturers who sell covered outpatient drugs to particular covered... provisions, which had been previously limited to the Alternative Methods Demonstration Project program. FOR...
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Li, Chenlei; Dai, Daoxin
2017-11-01
A polarization beam splitter (PBS) is proposed and realized for silicon photonic integrated circuits with a 340-nm-thick silicon core layer by introducing an asymmetric directional coupler (ADC), which consists of a silicon-on-insulator (SOI) nanowire and a subwavelength grating (SWG) waveguide. The SWG is introduced to provide an optical waveguide which has much higher birefringence than a regular 340-nm-thick SOI nanowire, so that it is possible to make the phase-matching condition satisfied for TE polarization only in the present design when the waveguide dimensions are optimized. Meanwhile, there is a significant phase mismatching for TM polarization automatically. In this way, the present ADC enables strong polarization selectivity to realize a PBS that separates TE and TM polarizations to the cross and through ports, respectively. The realized PBS has a length of ∼2 μm for the coupling region. For the fabricated PBS, the extinction ratio (ER) is 15-30 dB and the excess loss is 0.2-2.6 dB for TE polarization while the ER is 20-27 dB and the excess loss is 0.3-2.8 dB for TM polarization when operating in the wavelength range of 1520-1580 nm.
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Vault lining for 340 waste handling facility, 300 area
International Nuclear Information System (INIS)
Hollenbeck, R.G.
1997-01-01
Coating systems by Protection Enterprises, Ameron, Carboline, and Steelcote were evaluated. Each manufacturer has a coating system that is acceptable for use in the 340 Vault (see Appendix A). The choice of which system to use will be made after in-place adhesion tests are complete. The Protection Enterprises coating has the greatest potential for acceptable adhesion with minimal surface preparation. Total project cost for engineering and construction is $1,220,000 including 50% for contingency (see Appendix B). If the existing vault coverblock access hatch can satisfy entry requirements, $95,000 can be saved from the removal of coverblocks and the erection and disassembly of the greenhouse
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Thermal degradation of hexachlorobenzene in the presence of calcium oxide at 340-400 °C.
Yin, Keqing; Gao, Xingbao; Sun, Yifei; Zheng, Lei; Wang, Wei
2013-11-01
Hexachlorobenzene (HCB) in the milligram range was co-heated with calcium oxide (CaO) powder in sealed glass ampoules at 340-400 °C. The heated samples were characterized and analyzed by Raman spectroscopy, elemental analysis, gas chromatography/mass spectrometry, ion chromatography, and thermal/optical carbon analysis. The degradation products of HCB were studied at different temperatures and heated times. The amorphous carbon was firstly quantitatively evaluated and was thought to be important fate of the C element of HCB. The yield of amorphous carbon in products increased with heating time, for samples treated for 8h at 340, 380 °C and 400 °C, the value were 17.5%, 34.8% and 50.2%, respectively. After identification of the dechlorination products, the HCB degradation on CaO at 340-400 °C was supposed to through dechlorination/polymerization pathway, which is induced by electron transfer, generate chloride ions and form high-molecular weight intermediates with significant levels of both hydrogen and chlorine, and finally form amorphous carbon. Higher temperature was beneficial for the dechlorination/polymerization efficiency. The results are helpful for clarifying the reaction mechanism for thermal degradation of chlorinated aromatics in alkaline matrices. Copyright © 2013 Elsevier Ltd. All rights reserved.
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Directory of Open Access Journals (Sweden)
Rodrigo Ghiringhelli de Azevedo
2008-04-01
Full Text Available O presente artigo parte da reflexão acerca do papel da sociologia jurídica na compreensão do funcionamento da atividade legislativa, para analisar a racionalidade e os efeitos prováveis da entrada em vigor da Lei nº 11.340/06 (Lei Maria da Penha. Conclui-se que, ao invés de avançar e desenvolver mecanismos alternativos para a administração de conflitos, possivelmente mais eficazes para alcançar o objetivo de redução da violência, mais uma vez recorreu-se ao mito da tutela penal, neste caso ela própria uma manifestação da mesma cultura que se pretende combater.The present article makes a reflection upon the role of the Sociology of Law on understanding the operation of the legislative activity, in order to analyze rationality and the probable effects of Law N. 11.340/06 (Maria da Penha Law. One concluded that, instead of moving forward and developing alternative mechanisms for the administration of conflicts, possibly more effective to reduce violence, once more, one recurred to the myth of the penal protection, in this case, a manifestation of the same culture one intended to combat.
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International Nuclear Information System (INIS)
Longacre, R.S.
2011-01-01
In this paper we compare two models with central Au-Au collisions at √(ovr s NN )=200 GeV. The first model is a minijet model which assumes that around ∼50 minijets are produced in back-to-back pairs and have an altered fragmentation functions. It is also assumed that the fragments are transparent and escape the collision zone and are detected. The second model is a glasma flux tube model which leads to flux tubes on the surface of a radial expanding fireball driven by interacting flux tubes near the center of the fireball through plasma instabilities. This internal fireball becomes an opaque hydro fluid which pushes the surface flux tubes outward. Around ∼12 surface flux tubes remain and fragment with ∼1/2 the produced particles escaping the collision zone and are detected. Both models can reproduce two particle angular correlations in the different p t1 p t2 bins. We also compare the two models for three additional effects: meson baryon ratios; the long range nearside correlation called the ridge; and the so-called mach cone effect when applied to three particle angular correlations.
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Complete disintegration of heavy nuclei induced by 340 GeV negative pions
International Nuclear Information System (INIS)
Ahmad, T.; Tariq, M.; Irfan, M.; Zafar, M.; Ahsan, M.Z.; Shafi, M.
1989-01-01
The total disintegration of AgBr nuclei caused by 340 GeV negative pions is investigated. The probability of this phenomena depends on the energy of the pion projectile. The angular distributions of grey and black tracks are investigated. Results for the rapidity gap correlation in these catastrophic destructions are also presented. (author). 17 refs., 5 tabs., 9 figs
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Directory of Open Access Journals (Sweden)
J. Herman
2013-08-01
Full Text Available Measured upwelling radiances from Nimbus-7 SBUV (Solar Backscatter Ultraviolet and seven NOAA SBUV/2 instruments have been used to calculate the 340 nm Lambertian equivalent reflectivity (LER of the Earth from 1979 to 2011 after applying a common calibration. The 340 nm LER is highly correlated with cloud and aerosol cover because of the low surface reflectivity of the land and oceans (typically 2 to 6 RU, reflectivity units, where 1 RU = 0.01 = 1.0% relative to the much higher reflectivity of clouds plus nonabsorbing aerosols (typically 10 to 90 RU. Because of the nearly constant seasonal and long-term 340 nm surface reflectivity in areas without snow and ice, the 340 nm LER can be used to estimate changes in cloud plus aerosol amount associated with seasonal and interannual variability and decadal climate change. The annual motion of the Intertropical Convergence Zone (ITCZ, episodic El Niño Southern Oscillation (ENSO, and latitude-dependent seasonal cycles are apparent in the LER time series. LER trend estimates from 5° zonal average and from 2° × 5° , latitude × longitude, time series show that there has been a global net decrease in 340 nm cloud plus aerosol reflectivity. The decrease in cos2(latitude weighted average LER from 60° S to 60° N is 0.79 ± 0.03 RU over 33 yr, corresponding to a 3.6 ± 0.2% decrease in LER. Applying a 3.6% cloud reflectivity perturbation to the shortwave energy balance partitioning given by Trenberth et al. (2009 corresponds to an increase of 2.7 W m−2 of solar energy reaching the Earth's surface and an increase of 1.4% or 2.3 W m−2 absorbed by the surface, which is partially offset by increased longwave cooling to space. Most of the decreases in LER occur over land, with the largest decreases occurring over the US (−0.97 RU decade−1, Brazil (−0.9 RU decade−1, and central Europe (−1.35 RU decade−1. There are reflectivity increases near the west coast of Peru and Chile (0.8 ± 0.1 RU
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Arivazhagan, Roshini; Lee, Jaesuk; Bayarsaikhan, Delger; Kwak, Peter; Son, Myeongjoo; Byun, Kyunghee; Salekdeh, Ghasem Hosseini; Lee, Bonghee
2018-01-01
DNA Directed Polymerase Zeta Catalytic Subunit (REV3L) has recently emerged as an important oncogene. Although the expressions of REV3L are similar in normal and cancer cells, several mutations in REV3L have been shown to play important roles in cancer. These mutations cause proteins misfolding and mislocalization, which in turn alters their interactions and biological functions. miRNAs play important regulatory roles during the progression and metastasis of several human cancers. This study was undertaken to determine how changes in the location and interactions of REV3L regulate colon cancer progression. REV3L protein mislocalization confirmed from the immunostaining results and the known interactions of REV3L was found to be broken as seen from the PLA assay results. The mislocalized REV3L might interact with new proteins partners in the cytoplasm which in turn may play role in regulating colon cancer progression. hsa-miR-340 (miR-340), a microRNA down-regulated in colon cancer, was used to bind to and downregulate REV3L, and found to control the proliferation and induce the apoptosis of colon cancer cells (HCT-116 and DLD-1) via the MAPK pathway. Furthermore, this down-regulation of REV3L also diminished colon cancer cell migration, and down-regulated MMP-2 and MMP-9. Combined treatment of colon cancer cells with miR-340 and 5-FU enhanced the inhibitory effects of 5-FU. In addition, in vivo experiments conducted on nude mice revealed tumor sizes were smaller in a HCT-116-miR-340 injected group than in a HCT-116-pCMV injected group. Our findings suggest mutations in REV3L causes protein mislocalization to the cytoplasm, breaking its interaction and is believed to form new protein interactions in cytoplasm contributing to colon cancer progression. Accordingly, microRNA-340 appears to be a good candidate for colon cancer therapy. PMID:29435169
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International Nuclear Information System (INIS)
Vijayalakshmi, Kunadian; Kunadian, Babu; Wright, Robert A.; Hall, James A.; Stewart, Michael J.; Davies, Adrian; Sutton, Andrew; Belder, Mark A. de
2007-01-01
A new generation of intravascular contrast agents, the non-ionic monomers have safety profiles that are superior to those of older ionic compounds. There are, however, significant differences between these agents. Aim: The aim of this study was to determine the incidence of early ( 24 h to 7 days) reactions to two non-ionic contrast agents currently used during cardiac catheterisation: iopamidol 340 (Niopam TM Bracco UK Ltd.) and iomeprol 350 (Iomeron[reg] Bracco UK Ltd.). Methods: This was a prospective, randomised, double blinded trial. One thousand nine hundred and eighty-five patients undergoing cardiac catheterisation received one of the following contrast agents on a weekly basis: iopamidol 340 (Niopam TM ) and iomeprol 350 (Iomeron[reg]). Reactions that were possibly related to the contrast agents were recorded on predefined data collection forms during the first 24 h of the procedure (early reaction) and after 24 h to 7 days (late reaction) by means of a questionnaire. Results: The baseline characteristics were matched in both the groups. There was no significant difference in the incidence of heat sensation experienced between the two groups (p = 0.1). Early non-heat reactions occurred in 2.7% of patients receiving iopamidol 340 (Niopam TM ) and 4% of those receiving iomeprol 350 (Iomeron[reg]) (p = 0.1). Significant electrocardiographic changes were recorded in 1.7% of patients who received iopamidol 340 (Niopam TM ), and 1% of those who received iomeprol 350 (Iomeron[reg]) (p = 0.2). Bradycardia occurred more frequently in the iopamidol 350 group (0.8%) compared to the iomeprol 350 group (0.1%) p = 0.02. Late reactions occurred in 16.2% of those receiving iopamidol 340 (Niopam TM ) and 21.7% of those receiving iomeprol 350 (Iomeron[reg] (p = 0.02). A total of 23 (3.7%) patients in the iopamidol group and 39 (6.2%) patients in the iomeprol group reported nausea, p = 0.01. Conclusions: The incidence of early adverse reactions was similar with the two non
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A model for the massive binary V340 Muscae
Hauck, Norbert
2016-02-01
A synthetic light curve has been fitted to photometric data from the ASAS-3 database. The parameters of the best solution are well consistent with those derived from stellar models for both components for an initial metallicity Z=0.020 and a common age of 5 Myr. Therefore, we can reliably estimate the absolute dimensions of this close eclipsing binary system. Apparently, the O-type primary star has a mass of about 22.65 Msun and a radius of 10.35 Rsun. For the secondary star, likely a late B-type dwarf, we obtain about 3.1 Msun and 2.1 Rsun. Their mass ratio of about 0.138 might be the lowest found so far in O-type binaries. [English and German online-version of this paper available under www.bav-astro.eu/rb/rb2016-2/1.html].
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Leito, Jelani T. D.; Ligtenberg, Antoon J. M.; van Houdt, Michel; van den Berg, Timo K.; Wouters, Diana
2011-01-01
Salivary agglutinin (SAG), also known as gp-340 and Deleted in Malignant Brain Tumours 1, is a glycoprotein that is present in tears, lung fluid and mucosal surfaces along the gastrointestinal tract. It is encoded by the Deleted in Malignant Brain Tumours 1 gene, a member of the Scavenger Receptor
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Torres-Zafra, Juanita; Cellone, Sergio A.; Buzzoni, Alberto; Andruchow, Ileana; Portilla, José G.
2018-03-01
The BL Lac object 3C 66A is one of the most luminous extragalactic sources at TeV γ-rays (very high energy, i.e. E > 100 GeV). Since TeV γ-ray radiation is absorbed by the extragalactic background light (EBL), it is crucial to know the redshift of the source in order to reconstruct its original spectral energy distribution, as well as to constrain EBL models. However, the optical spectrum of this BL Lac is almost featureless, so a direct measurement of z is very difficult; in fact, the published redshift value for this source (z = 0.444) has been strongly questioned. Based on EBL absorption arguments, several constraints to its redshift, in the range 0.096 GMOS-N multi-object spectroscopy. We found spectroscopic evidence of two galaxy groups along the blazar's line of sight: one at z ≃ 0.020 and the second one at z ≃ 0.340. The first one is consistent with a known foreground structure, while the second group presented here has six spectroscopically confirmed members. Their location along a red sequence in the colour-magnitude diagram allows us to identify 34 additional candidate members of the more distant group. The blazar's spectrum shows broad absorption features that we identify as arising in the intergalactic medium, thus allowing us to tentatively set a redshift lower limit at z_3C66A ≳ 0.33. As a consequence, we propose that 3C 66A is hosted in a galaxy that belongs to a cluster at z = 0.340.
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78 FR 44016 - Exclusion of Orphan Drugs for Certain Covered Entities Under 340B Program
2013-07-23
... used. Once a hospital is enrolled in 340B, it may change its decision to purchase all orphan drugs... alternative system to tracking each discounted drug through the purchasing and dispensing process. (59 FR... the purchasing and dispensing process, to prove compliance. If an alternate system of tracking is...
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2010-01-01
... 12 Banks and Banking 4 2010-01-01 2010-01-01 false What are the restrictions on the sale of assets by the FDIC if the buyer wants to finance the purchase with a loan from the FDIC? 340.3 Section 340.3 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY RESTRICTIONS ON SALE OF ASSETS BY THE FEDERAL...
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Bayesian model comparison for one-dimensional azimuthal correlations in 200GeV AuAu collisions
Directory of Open Access Journals (Sweden)
Eggers Hans C.
2016-01-01
Full Text Available In the context of data modeling and comparisons between different fit models, Bayesian analysis calls that model best which has the largest evidence, the prior-weighted integral over model parameters of the likelihood function. Evidence calculations automatically take into account both the usual chi-squared measure and an Occam factor which quantifies the price for adding extra parameters. Applying Bayesian analysis to projections onto azimuth of 2D angular correlations from 200 GeV AuAu collisions, we consider typical model choices including Fourier series and a Gaussian plus combinations of individual cosine components. We find that models including a Gaussian component are consistently preferred over pure Fourier-series parametrizations, sometimes strongly so. For 0–5% central collisions the Gaussian-plus-dipole model performs better than Fourier Series models or any other combination of Gaussian-plus-multipoles.
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ISABELLE: a 200 + 200 GeV colliding beam facility
International Nuclear Information System (INIS)
Courant, E.D.
1977-01-01
Plans are under way for the construction of a pair of intersecting storage rings providing for colliding beams of protons of energy at least 200 GeV. The rings (circumference 2.62 km) will contain superconducting magnets constructed with braided Nb--Ti filamentary wire, with a peak field of 4.0 T corresponding to an energy of 200 GeV. A current of 10 A of protons will be injected at 29 GeV from the existing AGS accelerator at Brookhaven, using the energy stacking technique similar to that employed at the CERN ISR; subsequently the stored beam will be accelerated gradually in the storage rings. Six intersection areas will be provided for experiments. They are designed to provide flexibility in beam characteristics for different experiments. The maximum luminosity at full energy is expected to be 1.0 x 10 33 cm -2 s -1 , at 29 GeV it will be approximately 10 32 cm -2 s -1 . Recent work with prototype magnets indicates that fields of 5.0 T can be produced. This has led to an alternative design of somewhat larger rings (circumference 3.77 km) that should be capable of providing colliding beams at 400 + 400 GeV
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Implications of pion interferometry for O+Au at 200 A GeV
Energy Technology Data Exchange (ETDEWEB)
Gyulassy, M.; Padula, S.S.
1989-01-19
Recent NA35 data on O+Au -> ..pi../sup -/..pi../sup -/+X at 200 A GeV are shown to be consistent with both a hadronic resonance gas model and a quark-gluon plasma model for this reaction. We show, in addition, that much higher statistics data will be required to differentiate between these models even with the outward and sideward transverse projected correlation functions.
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Implications of pion interferometry for O+Au at 200 A GeV
International Nuclear Information System (INIS)
Gyulassy, M.; Padula, S.S.
1989-01-01
Recent NA35 data on O+Au → π - π - +X at 200 A GeV are shown to be consistent with both a hadronic resonance gas model and a quark-gluon plasma model for this reaction. We show, in addition, that much higher statistics data will be required to differentiate between these models even with the outward and sideward transverse projected correlation functions. (orig.)
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7 CFR 340.2 - Groups of organisms which are or contain plant pests and exemptions.
2010-01-01
... (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTRODUCTION OF ORGANISMS... plant pest in § 340.1. GROUP Viroids Superkingdom Prokaryotae Kingdom Virus All members of groups containing plant viruses, and all other plant and insect viruses Kingdom Monera Division Bacteria Family...
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76 FR 29183 - Exclusion of Orphan Drugs for Certain Covered Entities Under 340B Program
2011-05-20
... and, if they are, at what price. These covered entities do not know if they can buy these orphan drugs... DEPARTMENT OF HEALTH AND HUMAN SERVICES 42 CFR Part 10 RIN 0906-AA94 Exclusion of Orphan Drugs for... Prices of Drugs Purchased by Covered Entities.'' Section 340B implemented a drug pricing program by which...
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Directory of Open Access Journals (Sweden)
Anna Curry
Full Text Available Cell-surface CD200 expression by mouse EMT6 breast tumor cells increased primary tumor growth and metastasis to the draining lymph nodes (DLN in normal (WT BALB/c female recipients, while lack of CD200R1 expression in a CD200R1-/- host negated this effect. Silencing CD200 expression in EMT6siCD200 tumor cells also reduced their ability to grow and metastasize in WT animals. The cellular mechanisms responsible for these effects have not been studied in detail. We report characterization of tumor infiltrating (TILs and draining lymph node (DLN cells in WT and CD200-/- BALB/c mice, receiving WT tumor cells, or EMT6 lacking CD200 expression (EMT6siCD200 cells. Our data show an important correlation with augmented CD8+ cytotoxic T cells and resistance to tumor growth in mice lacking exposure (on either host cells or tumor to the immunoregulatory molecule CD200. Confirmation of the importance of such CD8+ cells came from monitoring tumor growth and characterization of the TILs and DLN cells in WT mice challenged with EMT6 and EMT6siCD200 tumors and treated with CD8 and CD4 depleting antibodies. Finally, we have assessed the mechanisms(s whereby addition of metformin as an augmenting chemotherapeutic agent in CD200-/- animals given EMT6 tumors and treated with a previously established immunotherapy regime can increase host resistance. Our data support the hypothesis that increased autophagy in the presence of metformin increases CD8+ responses and tumor resistance, an effect attenuated by the autophagy inhibitor verteporfin.
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Experience in automatic processing of 340.000 images from ITEF 3-m magnetic spectrometer
International Nuclear Information System (INIS)
Dzhelyadin, R.I.; Dukhovskoj, I.A.; Ivanov, L.V.; Kishkurno, V.V.; Krutenkova, A.P.; Kulikov, V.V.; Lyulevich, V.I.; Polikarpov, V.M.; Radkevich, I.A.; Fedorets, V.S.; Fedotov, O.P.
1974-01-01
A number of conclusions were made regarding automatic processing of 340.000 pictures (1.020.000 frames) developed on a three-meter magnetic spectrometer with spark chambers. Possibilities for time optimization of automatic processing programs are discussed. The results of processing of a series of photographs were analysed to compare the paramters of automatic ans semi-automatic processing. Some problems relating to organization and technology of picture processing are also autlined [ru
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Directory of Open Access Journals (Sweden)
Siddappa N Byrareddy
Full Text Available Lectin-like molecules and their receptors are cell surface molecules that have been shown to play a role in either facilitating infection or serving as transporters of HIV/SIV in vivo. The role of these lectin-like molecules in the pathogenesis of HIV/SIV infection continues to be defined. In efforts to gain further insight on the potential role of these lectin-like molecules, our laboratory generated monoclonal antibodies (mAb against the human analogs of rhesus macaque CD200, CD200R and Mincle, since the rhesus macaques are accepted as the most reliable animal model to study human HIV infection. The characterization of the cell lineages from the blood and various tissues of rhesus macaques that express these lectin-like molecules are described herein. Among the mononuclear cells, the cells of the myeloid lineage of rhesus macaques are the predominant cell lineages that express readily detectable levels of CD200, CD200R and Mincle that is similar to the expression of Siglec-1 and Siglec-3 reported by our laboratory earlier. Subset analysis revealed that a higher frequency of the CD14+/CD16- subset from normal rhesus macaques express CD200, CD200R and Mincle. Differences in the frequencies and density of expression of these molecules by the gated population of CD14+ cells from various tissues are noted with PBMC and bone marrow expressing the highest and the mononuclear cells isolated from the colon and ileum expressing the lowest levels. While a significant frequency of pDCs and mDCs express Siglec-1/Siglec-3, a much lower frequency expresses CD200, CD200R and Mincle in PBMCs from rhesus macaques. The mAb against CD200 and CD200R but not Mincle appear to inhibit the infection of macrophage tropic SIV/SHIV in vitro. We conclude that these mAbs may have potential to be used as adjunctive therapeutic agents to control/inhibit SIV/HIV infection.
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Multi-physics fluid-structure interaction modelling software
CSIR Research Space (South Africa)
Malan, AG
2008-11-01
Full Text Available -structure interaction modelling software AG MALAN AND O OXTOBY CSIR Defence, Peace, Safety and Security, PO Box 395, Pretoria, 0001 Email: amalan@csir.co.za – www.csir.co.za Internationally leading aerospace company Airbus sponsored key components... of the development of the CSIR fl uid-structure interaction (FSI) software. Below are extracts from their evaluation of the devel- oped technology: “The fi eld of FSI covers a massive range of engineering problems, each with their own multi-parameter, individual...
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17 CFR 200.26a - Office of Information Technology.
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Office of Information Technology. 200.26a Section 200.26a Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Organization § 200.26a Office of Information Technology. The Office of Information Technology is responsible...
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21 CFR 1404.200 - What is a covered transaction?
2010-04-01
... 21 Food and Drugs 9 2010-04-01 2010-04-01 false What is a covered transaction? 1404.200 Section 1404.200 Food and Drugs OFFICE OF NATIONAL DRUG CONTROL POLICY GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 1404.200 What is a covered transaction? A covered transaction is a...
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Linear thermal expansion measurements on silicon from 6 to 340 K
International Nuclear Information System (INIS)
Lyon, K.G.; Salinger, G.L.; Swenson, C.A.; White, G.K.
1977-01-01
Linear thermal expansion measurements have been carried out from 6 to 340 K on a high-purity silicon sample using a linear absolute capacitance dilatometer. The accuracy of the measurements varies from +- 0.01 x 10 -8 K -1 at the lowest temperatures to +- 0.1 x 10 -8 K -1 or 0.1%, whichever is greater, near room temperature, and is sufficient to establish silicon as a thermal expansion standard for these temperatures. The agreement with previous data is satisfactory at low temperatures and excellent above room temperature where laser-interferometry data of comparable accuracy exist. Thermal expansions calculated from ultrasonic and heat-capacity data are preferred below 13 K where experimental problems occurred
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Assonov, S; Taylor, P; Brenninkmeijer, C A M
2009-05-01
In 2007, JRC-IRMM began a series of atmospheric CO2 isotope measurements, with the focus on understanding instrumental effects, corrections as well as metrological aspects. The calibration approach at JRC-IRMM is based on use of a plain CO2 sample (working reference CO2) as a calibration carrier and CO2-air mixtures (in high-pressure cylinders) to determine the method-related correction under actual analytical conditions (another calibration carrier, in the same form as the samples). Although this approach differs from that in other laboratories, it does give a direct link to the primary reference NBS-19-CO2. It also helps to investigate the magnitude and nature for each of the instrumental corrections and allows for the quantification of the uncertainty introduced. Critical tests were focused on the instrumental corrections. It was confirmed that the use of non-symmetrical capillary crimping (an approach used here to deal with small samples) systematically modifies delta13C(CO2) and delta18O(CO2), with a clear dependence on the amount of extracted CO2. However, the calibration of CO2-air mixtures required the use of the symmetrical dual-inlet mode. As a proof of our approach, we found that delta13C(CO2) on extracts from mixtures agreed (within 0.010 per thousand) with values obtained from the 'mother' CO2 used for the mixtures. It was further found that very low levels of hydrocarbons in the pumping systems and the isotope ratio mass spectrometry (IRMS) instrument itself were critical. The m/z 46 values (consequently the calculated delta18O(CO2) values) are affected by several other effects with traces of air co-trapped with frozen CO2 being the most critical. A careful cryo-distillation of the extracted CO2 is recommended. After extensive testing, optimisation, and routine automated use, the system was found to give precise data on air samples that can be traced with confidence to the primary standards. The typical total combined uncertainty in delta13C(CO2) and
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Directory of Open Access Journals (Sweden)
A. B. Bayramov
2015-01-01
Full Text Available Application of dynamic modeling method upon ECAST to assess reactions of aircraft of Airbus type to random atmospheric disturbances without the use of Monte-Carlo method is considered. Application of the method will determine the significance of aircraft reactions to these disturbances, which will help in predicting the flight safety level.
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Irrigation vs. natural evacuation of left colostomy: a comparative study of 340 patients.
Terranova, O; Sandei, F; Rebuffat, C; Maruotti, R; Bortolozzi, E
1979-01-01
A comparative study of two methods of managing left colostomy (irrigation and natural evacuation) was carried out on 340 patients who were examined and interviewed at the Stoma Rehabilitation Clinic of the Institute of Surgical Pathology of the University of Padua. Ninety-two per cent of patients who irrigated their colostomies gained fecal continence. No patient who irrigated his colostomy had any cutaneous problem, and this group had significantly better results in preventing leakage of gas and odors compared with those patients using natural evacuation. For most patients who irrigated, the ability to predict or control bowel movements overcame fears of "being dirty" and related psychological problems. These patients also had more normal social and working lives than did those patients not irrigating their colostomies. Only one patient in our series had a colonic perforation, and any chance of a repeat incident will probably disappear with the cone-shaped catheters now available. The authors conclude that in properly selected patients, irrigation is the method of choice for management of left colostomy.
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The VASIMR[registered trademark] VF-200-1 ISS Experiment as a Laboratory for Astrophysics
Glover Tim W.; Squire, Jared P.; Longmier, Benjamin; Cassady, Leonard; Ilin, Andrew; Carter, Mark; Olsen, Chris S.; McCaskill, Greg; Diaz, Franklin Chang; Girimaji, Sharath;
2010-01-01
The VASIMR[R] Flight Experiment (VF-200-1) will be tested in space aboard the International Space Station (ISS) in about four years. It will consist of two 100 kW parallel plasma engines with opposite magnetic dipoles, resulting in a near zero-torque magnetic system. Electrical energy will come from ISS at low power level, be stored in batteries and used to fire the engine at 200 kW. The VF-200-1 project will provide a unique opportunity on the ISS National Laboratory for astrophysicists and space physicists to study the dynamic evolution of an expanding and reconnecting plasma loop. Here, we review the status of the project and discuss our current plans for computational modeling and in situ observation of a dynamic plasma loop on an experimental platform in low-Earth orbit. The VF-200-1 project is still in the early stages of development and we welcome new collaborators.
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In-Flight Observation of Gamma Ray Glows by ILDAS
Kochkin, Pavlo; van Deursen, A. P. J.; Marisaldi, M.; Ursi, A.; de Boer, A. I.; Bardet, M.; Allasia, C.; Boissin, J.-F.; Flourens, F.; Østgaard, N.
2017-12-01
An Airbus A340 aircraft flew over Northern Australia with the In-Flight Lightning Damage Assessment System (ILDAS) installed onboard. A long-duration gamma ray emission was detected. The most intense emission was observed at 12 km altitude and lasted for 20 s. Its intensity was 20 times the background counts, and it was abruptly terminated by a distant lightning flash. In this work we reconstruct the aircraft path and event timeline. The glow-terminating flash triggered a discharge from the aircraft wing that was recorded by a video camera operating onboard. Another count rate increase was observed 6 min later and lasted for 30 s. The lightning activity as reported by ground networks in this region was analyzed. The measured spectra characteristics of the emission were estimated.
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2013-08-22
... passengers. The Model 777-200, -300, and -300ER series airplanes have fly-by-wire controls, fully software... lead acid batteries and nickel cadmium batteries. These special conditions provide an equivalent level... characteristics that differ significantly from those of the nickel cadmium and lead acid rechargeable batteries...
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Energy Technology Data Exchange (ETDEWEB)
Vogel, C.
1996-04-01
The present work deals with mechanical behaviour of zirconium alpha at 200 deg. C and crack initiation prediction methods, particularly when loading conditions lead to interaction of fatigue and creep phenomena. A classical approach used to study interaction between cyclic effects and constant loading effects does not give easy understanding of experimental results. Therefore, a new approach has been developed, which allow to determine a number of cycles for crack initiation for complex structures under large loading conditions. To study influence of fatigue and creep interaction on crack initiation, a model was chosen, using a scalar variable, giving representation of the material deterioration state. The model uses a non linear cumulating effect between the damage corresponding to cyclic loads and the damage correlated to time influence. The model belongs to uncoupled approaches between damage and behaviour, which is described here by a two inelastic deformations model. This mechanical behaviour model is chosen because it allows distinction between a plastic and a viscous part in inelastic flow. Cyclic damage is function of stress amplitude and mean stress. For the peculiar sensitivity of the material to creep, a special parameter bas been defined to be critical toward creep damage. It is the kinematic term associated to state variables describing this type of hardening in the viscous mechanism. (author).
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Small passenger car transmission test-Chevrolet 200 transmission
Bujold, M. P.
1980-01-01
The small passenger car transmission was tested to supply electric vehicle manufacturers with technical information regarding the performance of commerically available transmissions which would enable them to design a more energy efficient vehicle. With this information the manufacturers could estimate vehicle driving range as well as speed and torque requirements for specific road load performance characteristics. A 1979 Chevrolet Model 200 automatic transmission was tested per a passenger car automatic transmission test code (SAE J651b) which required drive performance, coast performance, and no load test conditions. The transmission attained maximum efficiencies in the mid-eighty percent range for both drive performance tests and coast performance tests. Torque, speed and efficiency curves map the complete performance characteristics for Chevrolet Model 200 transmission.
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Hanford 200 Areas Development Plan
Energy Technology Data Exchange (ETDEWEB)
Rinne, C.A.; Daly, K.S.
1993-08-01
The purpose of the Hanford 200 Areas Development Plan (Development Plan) is to guide the physical development of the 200 Areas (which refers to the 200 East Area, 200 West Area, and 200 Area Corridor, located between the 200 East and 200 West Areas) in accordance with US Department of Energy (DOE) Order 4320.lB (DOE 1991a) by performing the following: Establishing a land-use plan and setting land-use categories that meet the needs of existing and proposed activities. Coordinating existing, 5-year, and long-range development plans and guiding growth in accordance with those plans. Establishing development guidelines to encourage cost-effective development and minimize conflicts between adjacent activities. Identifying site development issues that need further analysis. Integrating program plans with development plans to ensure a logical progression of development. Coordinate DOE plans with other agencies [(i.e., Washington State Department of Ecology (Ecology) and US Environmental Protection Agency (EPA)]. Being a support document to the Hanford Site Development Plan (DOE-RL 1990a) (parent document) and providing technical site information relative to the 200 Areas.
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Hanford 200 Areas Development Plan
International Nuclear Information System (INIS)
Rinne, C.A.; Daly, K.S.
1993-08-01
The purpose of the Hanford 200 Areas Development Plan (Development Plan) is to guide the physical development of the 200 Areas (which refers to the 200 East Area, 200 West Area, and 200 Area Corridor, located between the 200 East and 200 West Areas) in accordance with US Department of Energy (DOE) Order 4320.lB (DOE 1991a) by performing the following: Establishing a land-use plan and setting land-use categories that meet the needs of existing and proposed activities. Coordinating existing, 5-year, and long-range development plans and guiding growth in accordance with those plans. Establishing development guidelines to encourage cost-effective development and minimize conflicts between adjacent activities. Identifying site development issues that need further analysis. Integrating program plans with development plans to ensure a logical progression of development. Coordinate DOE plans with other agencies [(i.e., Washington State Department of Ecology (Ecology) and US Environmental Protection Agency (EPA)]. Being a support document to the Hanford Site Development Plan (DOE-RL 1990a) (parent document) and providing technical site information relative to the 200 Areas
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17 CFR 200.21a - The Ethics Counsel.
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false The Ethics Counsel. 200.21a...; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.21a The Ethics Counsel. (a) The Ethics Counsel within the Office of the General Counsel of the...
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International Nuclear Information System (INIS)
Momose, Munetake; Ohashi, Nagayoshi; Kudo, Tomoyuki; Tamura, Motohide; Kitamura, Yoshimi
2010-01-01
FN Tau is a rare example of a very low-mass T Tauri star that exhibits a spatially resolved nebulosity in near-infrared scattering light. To directly derive the parameters of a circumstellar disk around FN Tau, observations of dust continuum emission at 340 GHz are carried out with the Submillimeter Array (SMA). A point-like dust continuum emission was detected with a synthesized beam of ∼0.''7 in FWHM. From the analysis of the visibility plot, the radius of the emission is estimated to be ≤0.''29, corresponding to 41 AU. This is much smaller than the radius of the nebulosity, 1.''85 for its brighter part at 1.6 μm. The 340 GHz continuum emission observed with the SMA and the photometric data at λ ≤ 70 μm are explained by a power-law disk model whose outer radius and mass are 41 AU and (0.24-5.9) x 10 -3 M sun , respectively, if the exponent of dust mass opacity (β) is assumed to be 0-2. The disk model cannot fully reproduce the flux density at 230 GHz obtained with the IRAM 30 m telescope, suggesting that there is another extended 'halo' component that is missed in the SMA observations. By requiring the halo not to be detected with the SMA, the lower limit to the size of the halo is evaluated to be between 174 AU and 574 AU, depending on the assumed β value. This size is comparable to the near-infrared nebulosity, implying that the halo unseen with the SMA corresponds to the origin of the near-infrared nebulosity. The halo can contain mass comparable to or at most 8 times greater than that of the inner power-law disk, but its surface density should be lower than that at the outer edge of the power-law disk by more than 1 order of magnitude. The physical nature of the halo is unclear, but it may be the periphery of a flared circumstellar disk that is not described well in terms of a power-law disk model, or a remnant of a protostellar envelope having flattened structure.
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Bradshaw, James F.; Sandefur, Paul G., Jr.; Young, Clarence P., Jr.
1991-01-01
A comprehensive study of braze alloy selection process and strength characterization with application to wind tunnel models is presented. The applications for this study include the installation of stainless steel pressure tubing in model airfoil sections make of 18 Ni 200 grade maraging steel and the joining of wing structural components by brazing. Acceptable braze alloys for these applications are identified along with process, thermal braze cycle data, and thermal management procedures. Shear specimens are used to evaluate comparative shear strength properties for the various alloys at both room and cryogenic (-300 F) temperatures and include the effects of electroless nickel plating. Nickel plating was found to significantly enhance both the wetability and strength properties for the various braze alloys studied. The data are provided for use in selecting braze alloys for use with 18 Ni grade 200 steel in the design of wind tunnel models to be tested in an ambient or cryogenic environment.
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21 CFR 522.1660a - Oxytetracycline solution, 200 milligrams/milliliter.
2010-04-01
... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Oxytetracycline solution, 200 milligrams... FORM NEW ANIMAL DRUGS § 522.1660a Oxytetracycline solution, 200 milligrams/milliliter. (a) Specifications. Each milliliter of sterile solution contains 200 milligrams of oxytetracycline base. (b) Sponsors...
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24 CFR 200.926a - Residential building code comparison items.
2010-04-01
... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Residential building code comparison items. 200.926a Section 200.926a Housing and Urban Development Regulations Relating to Housing and... § 200.926a Residential building code comparison items. HUD will review each local and State code...
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Mathematical foundations of the dendritic growth models.
Villacorta, José A; Castro, Jorge; Negredo, Pilar; Avendaño, Carlos
2007-11-01
At present two growth models describe successfully the distribution of size and topological complexity in populations of dendritic trees with considerable accuracy and simplicity, the BE model (Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997) and the S model (Van Pelt and Verwer in Bull. Math. Biol. 48:197-211, 1986). This paper discusses the mathematical basis of these models and analyzes quantitatively the relationship between the BE model and the S model assumed in the literature by developing a new explicit equation describing the BES model (a dendritic growth model integrating the features of both preceding models; Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997). In numerous studies it is implicitly presupposed that the S model is conditionally linked to the BE model (Granato and Van Pelt in Brain Res. Dev. Brain Res. 142:223-227, 2003; Uylings and Van Pelt in Network 13:397-414, 2002; Van Pelt, Dityatev and Uylings in J. Comp. Neurol. 387:325-340, 1997; Van Pelt and Schierwagen in Math. Biosci. 188:147-155, 2004; Van Pelt and Uylings in Network. 13:261-281, 2002; Van Pelt, Van Ooyen and Uylings in Modeling Dendritic Geometry and the Development of Nerve Connections, pp 179, 2000). In this paper we prove the non-exactness of this assumption, quantify involved errors and determine the conditions under which the BE and S models can be separately used instead of the BES model, which is more exact but considerably more difficult to apply. This study leads to a novel expression describing the BE model in an analytical closed form, much more efficient than the traditional iterative equation (Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997) in many neuronal classes. Finally we propose a new algorithm in order to obtain the values of the parameters of the BE model when this growth model is matched to experimental data, and discuss its advantages and improvements over the more commonly used procedures.
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Nustar and Chandra insight into the nature of the 3-40 kev nuclear emission in NGC 253
DEFF Research Database (Denmark)
Lehmer, B. D.; Wik, D. R.; Hornschemeier, A. E.
2013-01-01
We present results from three nearly simultaneous Nuclear Spectroscopic Telescope Array ( NuSTAR ) and Chandra monitoring observations between 2012 September 2 and 2012 November 16 of the local star-forming galaxy NGC 253. The 3-40 keV intensity of the inner ~ 20 arcsec ( ~ 400 pc) nuclear region...
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Rodenko, Olga; Fodgaard, Henrik; Tidemand-Lichtenberg, Peter; Pedersen, Christian
2017-01-01
In immunoassay analyzers for in-vitro diagnostics, Xenon flash lamps have been widely used as excitation light sources. Recent advancements in UV LED technology and its advantages over the flash lamps such as smaller footprint, better wall-plug efficiency, narrow emission spectrum, and no significant afterglow, have made them attractive light sources for gated detection systems. In this paper, we report on the implementation of a 340 nm UV LED based time-resolved fluorescence system based on ...
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Plastic evolution behavior of H340LAD-Z steel by an optical method
Energy Technology Data Exchange (ETDEWEB)
Guo, Nan; Liang, Jin; Yu, Qiang; Qian, Boxing
2017-02-01
An optical method based on digital image correlation (DIC) technology was proposed to measure the plastic evolution of the high-strength low alloy steel H340LAD-Z. The basic principle of DIC technology is introduced, and then, the use of a 3D deformation measurement system and electronic universal testing machine to dynamically measure plastic evolution during the tensile yield stage is described. Through the full-field full-process measurement of plastic deformation during the yield stage in the 0°, 45° and 90° loading directions, the plastic evolution law was revealed. The results demonstrate that the proposed 3D DIC method can accurately reveal the starting and ending times for plastic evolution. The specimens in the three directions exhibit different plastic evolution behaviors, although they have similar yield strengths and yield times. The specimens in the 45° and 90° loading directions began to enter plastic deformation from bottom to top and the plastic area was maintained in a constant deformed state, while the evolution behavior in the 0° direction transited from both sides to the middle and plastic deformation was uneven. It is important to study plastic evolution of a metal sheet to determine the material properties and to provide an accurate basis for finite element modeling.
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Plastic evolution behavior of H340LAD-Z steel by an optical method
International Nuclear Information System (INIS)
Guo, Nan; Liang, Jin; Yu, Qiang; Qian, Boxing
2017-01-01
An optical method based on digital image correlation (DIC) technology was proposed to measure the plastic evolution of the high-strength low alloy steel H340LAD-Z. The basic principle of DIC technology is introduced, and then, the use of a 3D deformation measurement system and electronic universal testing machine to dynamically measure plastic evolution during the tensile yield stage is described. Through the full-field full-process measurement of plastic deformation during the yield stage in the 0°, 45° and 90° loading directions, the plastic evolution law was revealed. The results demonstrate that the proposed 3D DIC method can accurately reveal the starting and ending times for plastic evolution. The specimens in the three directions exhibit different plastic evolution behaviors, although they have similar yield strengths and yield times. The specimens in the 45° and 90° loading directions began to enter plastic deformation from bottom to top and the plastic area was maintained in a constant deformed state, while the evolution behavior in the 0° direction transited from both sides to the middle and plastic deformation was uneven. It is important to study plastic evolution of a metal sheet to determine the material properties and to provide an accurate basis for finite element modeling.
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Modeling of creep-fatigue interaction of zirconium α under cyclic loading at 200 C
International Nuclear Information System (INIS)
Vogel, C.
1996-04-01
The present work deals with mechanical behaviour of zirconium alpha at 200 deg. C and crack initiation prediction methods, particularly when loading conditions lead to interaction of fatigue and creep phenomena. A classical approach used to study interaction between cyclic effects and constant loading effects does not give easy understanding of experimental results. Therefore, a new approach has been developed, which allow to determine a number of cycles for crack initiation for complex structures under large loading conditions. To study influence of fatigue and creep interaction on crack initiation, a model was chosen, using a scalar variable, giving representation of the material deterioration state. The model uses a non linear cumulating effect between the damage corresponding to cyclic loads and the damage correlated to time influence. The model belongs to uncoupled approaches between damage and behaviour, which is described here by a two inelastic deformations model. This mechanical behaviour model is chosen because it allows distinction between a plastic and a viscous part in inelastic flow. Cyclic damage is function of stress amplitude and mean stress. For the peculiar sensitivity of the material to creep, a special parameter bas been defined to be critical toward creep damage. It is the kinematic term associated to state variables describing this type of hardening in the viscous mechanism. (author)
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International Nuclear Information System (INIS)
Hong, Byung Sik
1999-01-01
The energy dependence of the thermodynamical parameters in nucleus-nucleus collisions are studied from 1A to 200A GeV in the framework of the statistical thermal model. The energy and entropy densities, as well as the pressure, of hot and dense hadronic matter are calculated by using the available input parameters of the model. No discontinuity or steep rise in the thermodynamical parameters has been found. The equation of state in terms of the speed of sound is investigated as a function of the energy density, and it increases monotonically up to 200A GeV. The estimated sonic velocities above 10A GeV are very close to that of an ideal ultrarelativistic hadron gas in the presence of resonances
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2010-04-01
... furnish advisory services in connection with the financing or construction of a project and the related... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Definitions. 200.215 Section 200... Participation Review and Clearance Procedure § 200.215 Definitions. (a) Affiliate. Any person or business...
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Blot, R.; Nedelec, P.; Petetin, H.; Thouret, V.; Cohen, Y.
2017-12-01
The In-Service Aircraft for a Global Observing System (IAGOS; http://www.iagos.org) is an European Research Infrastructure that provides cost-effective global atmospheric composition measurements at high resolution using commercial passenger aircraft. It is the continuation of the MOZAIC (1994-2014) and the CARIBIC (since 1997) programs that has provided a unique scientific database using 6 aircraft operated by European airlines over two decades. Thanks to growing interests of several international Airlines to contribute to the academic climate research, the IAGOS aircraft fleet (started in 2011), with the IAGOS-CORE basic instrumentation, has expanded to 9 Airbus A340/A330 aircraft up to now. Here, we present this IAGOS-CORE instrumentation that continuously sample carbon monoxide, ozone, water vapor and cloud droplets. We focus on carbon monoxide and ozone measurements which are performed by optimized, but well known, methods such as UV absorption and IR correlation. We describe the data processing/validation and the data quality control. With already more than 20 and 15 years of continuous ozone and carbon monoxide measurements, respectively, the IAGOS/MOZAIC data are particularly suitable for climatologies and trends. Also, since commercial aircraft are daily operated, the near-real time IAGOS-CORE data are also used to observe pollution plumes and to validate air-quality models as well as satellite products.
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Hydrodynamical assessment of 200A GeV collisions
International Nuclear Information System (INIS)
Schnedermann, E.; Heinz, U.
1994-01-01
We are analyzing the hydrodynamics of 200A GeV S+S collisions using a new approach which tries to quantify the uncertainties arising from the specific implementation of the hydrodynamical model. Based on a previous phenomenological analysis we use the global hydrodynamics model to show that the amount of initial flow, or initial energy density, cannot be determined from the hadronic momentum spectra. We additionally find that almost always a sizable transverse flow develops, which causes the system to freeze out, thereby limiting the flow velocity in itself. This freeze-out dominance in turn makes a distinction between a plasma and a hadron resonance gas equation of state very difficult, whereas a pure pion gas can easily be ruled out from present data. To complete the picture we also analyze particle multiplicity data, which suggest that chemical equilibrium is not reached with respect to the strange particles. However, the overpopulation of pions seems to be at most moderate, with a pion chemical potential far away from the Bose divergence
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24 CFR 200.929a - Fair Housing Accessibility Guidelines.
2010-04-01
... Guidelines. 200.929a Section 200.929a Housing and Urban Development Regulations Relating to Housing and Urban... Fair Housing Accessibility Guidelines. Builders and developers may use the Department's Fair Housing Accessibility Guideline when designing or constructing covered multifamily dwelling units in order to comply...
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2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Publication. 200.13 Section 200.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INFORMAL RULES OF PRACTICE FOR PASSENGER SERVICE § 200.13 Publication. (a) General notice of any...
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2010-07-01
... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Where hazardous... Provisions Relating to Hazardous Substance Activity § 102-75.340 Where hazardous substance activity has been... offer to purchase and the conveyance document? Where the existence of hazardous substance activity has...
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45 CFR 2555.200 - Application.
2010-10-01
... 45 Public Welfare 4 2010-10-01 2010-10-01 false Application. 2555.200 Section 2555.200 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE... Coverage § 2555.200 Application. Except as provided in §§ 2555.205 through 2555.235(a), these Title IX...
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International Nuclear Information System (INIS)
Madland, D.
1997-01-01
Conclusions of the specialists meeting on the nucleon-nucleus optical model up to 200 MeV are drawn, from both the experimental and the theoretical point of view. Five general approaches to the medium-energy optical potential are discussed: Dirac and Schroedinger phenomenological potentials, dispersive potentials, semi-microscopic potentials, microscopic potentials and coupled-channel potentials. (K.A.)
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International Nuclear Information System (INIS)
Yue Ning; Nath, Ravinder
2002-01-01
Since the publication of the AAPM Task Group 43 report in 1995, Model 200 103 Pd seed, which has been widely used in prostate seed implants and other brachytherapy procedures, has undergone some changes in its internal geometry resulting from the manufacturer's transition from lower specific activity reactor-produced 103 Pd ('heavy seeds') to higher specific activity accelerator-produced radioactive material ('light seeds'). Based on previously reported theoretical calculations and measurements, the dose rate constants and the radial dose functions of the two types of seeds are nearly the same and have already been reported. In this work, the anisotropy function of the 'light seed' was experimentally measured and an averaging method for the determination of the anisotropy constant from distance-dependent values of anisotropy factors is presented based upon the continuous low dose rate irradiation linear quadratic model for cell killing. The anisotropy function of Model 200 103 Pd 'light seeds' was measured in a Solid Water trade mark sign phantom using 1x1x1 mm micro LiF TLD chips at radial distances of 1, 2, 3, 4, 5, and 6 cm and at angles from 0 to 90 deg. with respect to the longitudinal axis of the seeds. At a radial distance of 1 cm, the measured anisotropy function of the 103 Pd 'light seed' is considerably lower than that of the 103 Pd 'heavy seed' reported in the TG 43 report. Our measured values at all radial distances are in excellent agreement with the results of a Monte Carlo simulation reported by Weaver, except for points along and near the seed longitudinal axis. The anisotropy constant of the 103 Pd 'light seed' was calculated using the linear quadratic biological model for cell killing in 30 clinical implants. For the model 200 ''light seed,'' it has a value of 0.865. However, our biological model calculations lead us to conclude that if the anisotropy factors of an interstitial brachytherapy seed vary significantly over radial distances anisotropy
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A P + DEUTERON PROTON POLARIMETER AT 200 MEV.
Energy Technology Data Exchange (ETDEWEB)
HUANG,H.; ROSER,T.; ZELENSKI,A.; KURITA,K.; STEPHENSON,E.; TOOLE,R.
2002-06-02
There has been concern about the analyzing power of the p-Carbon polarimeter at the end of 200 MeV LINAC of BNL. A new polarimeter based on proton-deuteron scattering was installed and we have repeated the calibration of proton-Carbon scattering at 12 degrees and 200 MeV against proton-deuteron scattering. The result is consistent with the value of A=0.62 now used to measure the beam polarization at the end of the LINAC.
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2010-04-01
... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Yogurt. 131.200 Section 131.200 Food and Drugs... CONSUMPTION MILK AND CREAM Requirements for Specific Standardized Milk and Cream § 131.200 Yogurt. (a) Description. Yogurt is the food produced by culturing one or more of the optional dairy ingredients specified...
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2010-04-01
... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Application. 3.200 Section 3.200 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... Coverage § 3.200 Application. Except as provided in §§ 3.205 through 3.235(a), these Title IX regulations...
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Catch tanks inhibitor addition 200-East and 200-West Areas
International Nuclear Information System (INIS)
Palit, A.N.
1996-01-01
Reported is the study of 11 catch tanks in the 200-East Area and the 7 catch tanks in the 200-West Area listed as active. The location, capacity, material of construction, annual total accumulation, annual rain intrusion, waste transfer rate, and access for chemical injection in these tanks are documented. The present and future utilization and isolation plans for the catch tanks are established
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200 GW for Germany; 200 Gigawatt fuer Deutschland
Energy Technology Data Exchange (ETDEWEB)
Fuhs, Michael; Enkhardt, Sandra
2012-11-01
200 GW of solar power, i.e. seven times as much as today: Is that a realistic goal, or is it just propaganda for a lobby intending to make a good life for manufacturers and fitters? There is much to suggest that it may be a socially relevant goal.
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DEFF Research Database (Denmark)
Madsen, Jens; Tornøe, Ida; Nielsen, Ole
2003-01-01
CRP-ductin is a protein expressed mainly by mucosal epithelial cells in the mouse. Sequence homologies indicate that CRP-ductin is the mouse homologue of human gp-340, a glycoprotein that agglutinates microorganisms and binds the lung mucosal collectin surfactant protein-D (SP-D). Here we report...... that purified CRP-ductin binds human SP-D in a calcium-dependent manner and that the binding is not inhibited by maltose. The same properties have previously been observed for gp-340 binding of SP-D. CRP-ductin also showed calcium-dependent binding to both gram-positive and -negative bacteria. A polyclonal...... antibody raised against gp-340 reacted specifically with CRP-ductin in Western blots. Immunoreactivity to CRP-ductin was found in the exocrine pancreas, in epithelial cells throughout the gastrointestinal tract and in the parotid ducts. A panel of RNA preparations from mouse tissues was screened for CRP...
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Prospects for the Higgs boson in e+e- collisions at LEP 200
International Nuclear Information System (INIS)
Gross, E.; Lellouch, D.; Read, A.L.
1998-05-01
The authors evaluate the combined sensitivity of the four LEP collaborations to exclude or discover the Standard Model Higgs boson with the LEP collider at centre-of-mass energies of 189-200 GeV. It is argued that neighter Standard Model nor the Supersymmetric Higgs search benefits from an upgrade of LEP to its peak centre-of-mass energy (e.g. upgrade 198 GeV to 200 GeV) if this degrades the integrated luminosity by a factor of two or more. 7 refs., 11 figs
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International Nuclear Information System (INIS)
Jiang, Z; Christenson, R
2011-01-01
Control devices can be used to dissipate the energy of a civil structure subjected to dynamic loading, such as earthquake, wave and wind excitation, thus reducing structural damage and preventing failure. The magneto-rheological (MR) fluid damper is a promising device for use in civil structures due to its mechanical simplicity, inherent stability, high dynamic range, large temperature operating range, robust performance, and low power requirements. The MR damper is intrinsically nonlinear and rate dependent. Thus a challenging aspect of applying this technology is the development of accurate models to describe the behavior of such dampers for control design and evaluation purposes. In particular, a new type of experimental testing called real-time hybrid simulation (RTHS) combines numerical simulation with laboratory testing of physical components. As with any laboratory testing, safety is of critical importance. For RTHS in particular the feedback and dynamic interaction of physical and numerical components can result in potentially unstable behavior. For safety purposes, it is desired to conduct pretest simulations where the physical specimen is replaced with an appropriate numerical model yet the numerical RTHS component is left unchanged. These pretest simulations require a MR damper model that can exhibit stability and convergence at larger fixed integration time steps, and provide computational efficiency, speed of calculation, and accuracy during pretest verification of the experimental setup. Several models for MR dampers have been proposed, including the hyperbolic tangent, Bouc–Wen, viscous plus Dahl and algebraic models. This paper examines the relative performance of four MR damper models of large-scale 200 kN MR dampers as needed for pretest simulations of RTHS. Experimental tests are conducted on two large-scale MR dampers located at two RTHS test facilities at the Smart Structures Technology Laboratory at the University of Illinois at Urbana
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EXPLORAÇÃO DO CONCEITO DE VIOLÊNCIA PSICOLÓGICA NA LEI 11.340/06
Vier Machado, Isadora; Dezanoski, Mayara
2014-01-01
A cultura de submissão das mulheres em relação aos homens, continua presente na atual sociedade e favorece, em grande medida, os índices do fenômeno de violência doméstica. Desta forma, diante da insuficiência protetiva às mulheres, houve a necessidade da criação da Lei 11.340/06, também conhecida como Lei Maria da Penha, que instituiu as diversas formas de violências a serem prevenidas ou enfrentadas; dentre elas, a violência psicológica, sem, contudo, criminalizá-las, ao passo que, como ser...
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Superhigh-resolution 200ppi series TFT-LCDs; Chokoseisai 200ppi ekisho display series
Energy Technology Data Exchange (ETDEWEB)
Kawamata, K.; Hirai, H. [Toshiba Corp., Tokyo (Japan)
2000-02-01
We have developed a 202 pixels per inch (ppi) thin-film transistor liquid crystal display (TFT-LCD) using low-temperature polycrystalline silicon (LTPS) technology. The superhigh resolution of 202 ppi offers the same image quality as printed matter such as magazines. The 200 ppi series TFT-LCDs are expected to support further developments in such areas as electronic books (e-books) and personal digital-picture viewers. Our lineup of 200 ppi TFT-LCDs includes a 4-inch display with VGA resolution, which is suitable for palmtop-size applications, and a 6.3-inch display with XGA resolution, which is suitable for typical photograph or paperback book-size applications. Larger size LCDs with 200 ppi resolution will be developed. (author)
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Preliminary Core Design Analysis of a 200MWth Pebble Bed-type VHTR
International Nuclear Information System (INIS)
Jo, Chang Keun; Noh, Jae Man
2007-01-01
This paper intends to suggest the preliminary core design analysis of a VHTR for a hydrogen production. The nuclear hydrogen system that utilizes the high temperature heat generated from the VHTR is a promising candidate for a cost effective, safe and clean supply of hydrogen in the age of hydrogen economy. Among two candidate VHTR cores, that is, a prismatic modular reactor (PMR) and a pebble bed-type reactor (PBR), we focus on the design of a 200MWth PBR (hereinafter PBR200) in this paper. Here, the 200MWth power is selected for a demonstration plant. The core configuration of the PBR200 is similar to the PBMR (Pebble Bed Modular Reactor, 400MWth) of South Africa, but the overall dimension of the reactor system is scaled-down. This paper is to suggest two candidate PBR200 cores. One is an annular core with an inner reflector (PBR200-CD1) which was presented at IWRES07, and the other is a cylindrical core without an inner reflector (PBR200-CD2)
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2010-07-01
... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Application. 54.200 Section 54.200 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 54.200 Application...
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2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Application. 200.602 Section 200.602 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT... Programs or Activities Conducted by the Securities and Exchange Commission § 200.602 Application. This...
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2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Purpose. 200.550 Section 200.550 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Regulations Pertaining to the Protection of the Environment § 200...
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miR-200–containing extracellular vesicles promote breast cancer cell metastasis
Le, Minh T.N.; Hamar, Peter; Guo, Changying; Basar, Emre; Perdigão-Henriques, Ricardo; Balaj, Leonora; Lieberman, Judy
2014-01-01
Metastasis is associated with poor prognosis in breast cancer patients. Not all cancer cells within a tumor are capable of metastasizing. The microRNA-200 (miR-200) family, which regulates the mesenchymal-to-epithelial transition, is enriched in the serum of patients with metastatic cancers. Ectopic expression of miR-200 can confer metastatic ability to poorly metastatic tumor cells in some settings. Here, we investigated whether metastatic capability could be transferred between metastatic and nonmetastatic cancer cells via extracellular vesicles. miR-200 was secreted in extracellular vesicles from metastatic murine and human breast cancer cell lines, and miR-200 levels were increased in sera of mice bearing metastatic tumors. In culture, murine and human metastatic breast cancer cell extracellular vesicles transferred miR-200 microRNAs to nonmetastatic cells, altering gene expression and promoting mesenchymal-to-epithelial transition. In murine cancer and human xenograft models, miR-200–expressing tumors and extracellular vesicles from these tumors promoted metastasis of otherwise weakly metastatic cells either nearby or at distant sites and conferred to these cells the ability to colonize distant tissues in a miR-200–dependent manner. Together, our results demonstrate that metastatic capability can be transferred by the uptake of extracellular vesicles. PMID:25401471
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2010-04-01
... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Prescription drugs; reminder advertisements and reminder labeling to provide price information to consumers. 200.200 Section 200.200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL GENERAL Prescription Drug Consumer Price Listing §...
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2010-10-01
... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Application. 19.200 Section 19.200 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 19.200 Application. Except as provided in §§ 19.205...
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14 CFR 1253.200 - Application.
2010-01-01
... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Application. 1253.200 Section 1253.200 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 1253.200 Application...
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2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Authority. 200.50 Section 200.50 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.50 Authority. The Canons of Ethics for...
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2010-10-01
... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Application. 41.200 Section 41.200 Public Lands: Interior Office of the Secretary of the Interior NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Coverage § 41.200 Application...
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15 CFR 200.106 - Publications.
2010-01-01
... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Publications. 200.106 Section 200.106... FEES § 200.106 Publications. Publications provide the primary means of communicating the results of the... issues some fifteen categories of publications including three periodicals, ten non-periodicals series...
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2010-04-01
... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Authority. 200.605 Section 200.605... GENERAL INTRODUCTION TO FHA PROGRAMS Affirmative Fair Housing Marketing Regulations § 200.605 Authority. The regulations in this subpart are issued pursuant to the authority to issue regulations granted to...
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Energy Technology Data Exchange (ETDEWEB)
Get' man, V.A.; Gorbenko, V.G.; Grushin, V.F.; Derkach, A.Y.; Zhebrovskii, Y.V.; Karnaukhov, I.M.; Kolesnikov, L.Y.; Lukhanin, A.A.; Rubashkin, A.L.; Sanin, V.M.; Sorokin, P.V.; Sporov, E.A.; Telegin, Y.N.
1979-07-05
A two-fold polarization experiment of the ''beam-target'' type is carried out for the first time for the reaction ..gamma..p..-->..n..pi../sup +/ for E/sub ..gamma../ =340 MeV, and the three polarization parameters, ..sigma.., T, and P are determined simultaneously.
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24 CFR 200.47 - Firm commitments.
2010-04-01
... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Firm commitments. 200.47 Section 200.47 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Eligibility Requirements for Existing Projects Commitment Applications § 200.47 Firm commitments. A valid firm...
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Directory of Open Access Journals (Sweden)
Varun Sheel
2016-05-01
Full Text Available This article is based on the study of the seasonal and interannual variability of carbon monoxide (CO and ozone (O3 at different altitudes of the troposphere over Hyderabad, India, during 2006–2010 using Measurement of OZone and water vapour by Airbus In-Service Aircraft (MOZAIC and observation from Tropospheric Emission Spectrometer (TES aboard NASA's Aura satellite. The MOZAIC observations show maximum seasonal variability in both CO and O3 during winter and pre-monsoon season, with CO in the range (100–200±13 ppbv and O3 in the range (50–70±9 ppbv. The time-series of MOZAIC data shows a significant increase of 4.2±1.3 % in the surface CO and 6.7±1.3 % in the surface O3 during 2006–2010 in Hyderabad. From MOZAIC observations, we identify CO and O3 profiles that are anomalous with respect to the monthly mean and compare those with Weather Research Forecast model coupled with Chemistry (WRF-Chem and Model for OZone and Related Tracers, version 4 profiles for the same day. The anomalous profiles of WRF-Chem are simulated using three convection schemes. The goodness of comparison depends on the convection scheme and the altitude region of the troposphere.
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Scalas , Giulia
2015-01-01
International audience; In this paper I aim at analysing one passage of the Refutatio omnium haeresium (I 22, 5 = 340 Usener) to understand whether it is consistent with the Epicurean doctrine of soul. First, I provide an account of the historical context of the Refutatio. Secondly, I provide a comparison between the content of the passage and the Epicurean psychology. As a result, the theory according to which " souls are blood " , which occurs in the passage, appears to be inconsistent with...
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46 CFR 117.200 - Survival craft-general.
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft-general. 117.200 Section 117.200 Shipping... Number and Type of Survival Craft § 117.200 Survival craft—general. (a) Each survival craft required on a... craft they replace. (c) A summary of survival craft requirements is provided in Table 117.200(c). Table...
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6 CFR 27.200 - Information regarding security risk for a chemical facility.
2010-01-01
... chemical facility. 27.200 Section 27.200 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.200 Information regarding security risk for a chemical facility. (a) Information to determine security risk. In order to...
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LEI 11.340/2006: SEU CONTEXTO, CONTEÚDO E APLICAÇÃO.
Directory of Open Access Journals (Sweden)
Carolina Vicente Bisognin
2007-12-01
Full Text Available Entrou em vigor, em setembro de 2006, a lei 11.340/2006, também conhecida como Lei Maria da Penha, em homenagem à senhora que através de suas tragédias pessoais propiciou a elaboração da lei. Tal conjunto normativo é considerado uma forma de discriminação positiva, ao lado de outros marcos regulatórios, como o Estatuto da criança e do Adolescente e Estatuto do Idoso. A nova lei regulamenta os casos de violência doméstica, trazendo diversas mudanças, dentre as quais vale destacar as do processo judicial, do resgate do inquérito policial, do papel participativo da autoridade policial, além das alterações no Código Penal, Código de Processo Penal e Lei de Execução Penal.
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Contacting graphene in a 200 mm wafer silicon technology environment
Lisker, Marco; Lukosius, Mindaugas; Kitzmann, Julia; Fraschke, Mirko; Wolansky, Dirk; Schulze, Sebastian; Lupina, Grzegorz; Mai, Andreas
2018-06-01
Two different approaches for contacting graphene in a 200 mm wafer silicon technology environment were tested. The key is the opportunity to create a thin SiN passivation layer on top of the graphene protecting it from the damage by plasma processes. The first approach uses pure Ni contacts with a thickness of 200 nm. For the second attempt, Ni is used as the contact metal which substitutes the Ti compared to a standard contact hole filling process. Accordingly, the contact hole filling of this "stacked via" approach is Ni/TiN/W. We demonstrate that the second "stacked Via" is beneficial and shows contact resistances of a wafer scale process with values below 200 Ohm μm.
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24 CFR 200.83 - Interest rate.
2010-04-01
... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Interest rate. 200.83 Section 200... Eligibility Requirements for Existing Projects Mortgage Provisions § 200.83 Interest rate. (a) The mortgage shall bear interest at the rate agreed upon by the mortgagee and the mortgagor. (b) Interest shall be...
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Branco, Claudia C; Gomes, Cidália T; De Fez, Laura; Bulhões, Sara; Brilhante, Maria José; Pereirinha, Tânia; Cabral, Rita; Rego, Ana Catarina; Fraga, Cristina; Miguel, António G; Brasil, Gracinda; Macedo, Paula; Mota-Vieira, Luisa
2015-01-01
Iron overload is associated with acquired and genetic conditions, the most common being hereditary hemochromatosis (HH) type-I, caused by HFE mutations. Here, we conducted a hospital-based case-control study of 41 patients from the São Miguel Island (Azores, Portugal), six belonging to a family with HH type-I pseudodominant inheritance, and 35 unrelated individuals fulfilling the biochemical criteria of iron overload compatible with HH type-I. For this purpose, we analyzed the most common HFE mutations- c.845G>A [p.Cys282Tyr], c.187C>G [p.His63Asp], and c.193A>T [p.Ser65Cys]. Results revealed that the family's HH pseudodominant pattern is due to consanguineous marriage of HFE-c.845G>A carriers, and to marriage with a genetically unrelated spouse that is a -c.187G carrier. Regarding unrelated patients, six were homozygous for c.845A, and three were c.845A/c.187G compound heterozygous. We then performed sequencing of HFE exons 2, 4, 5 and their intron-flanking regions. No other mutations were observed, but we identified the -c.340+4C [IVS2+4C] splice variant in 26 (74.3%) patients. Functionally, the c.340+4C may generate alternative splicing by HFE exon 2 skipping and consequently, a protein missing the α1-domain essential for HFE/ transferrin receptor-1 interactions. Finally, we investigated HFE mutations configuration with iron overload by determining haplotypes and genotypic profiles. Results evidenced that carriers of HFE-c.187G allele also carry -c.340+4C, suggesting in-cis configuration. This data is corroborated by the association analysis where carriers of the complex allele HFE-c.[187C>G;340+4T>C] have an increased iron overload risk (RR = 2.08, 95% CI = 1.40-2.94, poverload because they will produce two altered proteins--the p.63Asp [c.187G], and the protein lacking 88 amino acids encoded by exon 2. In summary, we provide evidence that the complex allele HFE-c.[187C>G;340+4T>C] has a role, as genetic predisposition factor, on iron overload in the S
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Energy Technology Data Exchange (ETDEWEB)
Jincai, Li; Zuying, Gao; Baocheng, Xu; Junxiao, He [Institute of Nuclear Energy and Technology, Tsingua Univ., Beijing (China)
1997-09-01
The NHR-200 is a commercial 200-MW District Heating Reactor developed in China. It is designed on the basis of design, construction and four-year operating experience of the 5MW Experimental Heating Reactor (NHR-5). It has special safety features which are briefly described in this paper. Accident classification and safety criteria are also explained. Some typical and serious accidents are studied theoretically, and their results are detailed in this paper. They demonstrate the excellent safety characteristics of HR-200. (author). 4 refs, 9 figs, 1 tab.
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2010-10-01
... 49 Transportation 2 2010-10-01 2010-10-01 false Welding. 179.200-10 Section 179.200-10... Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.200-10 Welding. (a) All joints... W (IBR, see § 171.7 of this subchapter). Welding procedures, welders and fabricators shall be...
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10 CFR 1021.200 - DOE planning.
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false DOE planning. 1021.200 Section 1021.200 Energy DEPARTMENT... Decisionmaking § 1021.200 DOE planning. (a) DOE shall provide for adequate and timely NEPA review of DOE... accordance with 40 CFR 1501.2 and this section. In its planning for each proposal, DOE shall include adequate...
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Strangeness production in p+Pb reactions at 200 GeV/c
International Nuclear Information System (INIS)
Greiner, D.E.; Andersen, E.; Blaes, R.; Cherney, M.; Cruz, B. de la; Fernandez, C.; Garabatos, C.; Garzon, J.A.; Geist, W.M.; Gruhn, C.R.; Hafidouni, M.; Hrubec, J.; Jones, P.G.; Judd, E.G.; Kuipers, J.P.M.; Ladrem, M.; Ladron de Guevara, P.; Loevhoeiden, G.; MacNaughton, J.; Mosquera, J.; Natkaniec, Z.; Nelson, J.M.; Neuhofer, G.; Perez de los Heros, C.; Plo, M.; Porth, P.; Powell, B.; Ramil, A.; Rohringer, H.; Sakrejda, I.; Thorsteinsen, T.F.; Traxler, J.; Voltolini, C.; Wozniak, K.; Yanez, A.; Zybert, R.
1994-01-01
The production of the strange particles Λ, anti Λ and K S 0 in p+Pb collisions at 200 GeV/c has been measured using the NA36 TPC. Rapidity distributions and multiplicity dependences are presented and compared to model calculations. Reinteractions in the target are important to describe the observed spectra. Inverse slopes T∼200 MeV are extracted from the transverse mass distributions. (orig.)
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A five year study on the susceptibility of isolates from various parts of ...
African Journals Online (AJOL)
tests. The various isolates for the five-year period were Staphylococcus aureus 1000, Klebsiella pneumoniae 340, Proteus mirabilis 38 Escherichia coli 295, Pseudomonas aeroginosa 240, Alcaligenes faecalis 200, Enterobacter aerogenes 175, Acinetobacter baumannii 150, Proteus vulgaris 110, Providencia stuartii 101, ...
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Design and initial characterization of the SC-200 proteomics standard mixture.
Bauman, Andrew; Higdon, Roger; Rapson, Sean; Loiue, Brenton; Hogan, Jason; Stacy, Robin; Napuli, Alberto; Guo, Wenjin; van Voorhis, Wesley; Roach, Jared; Lu, Vincent; Landorf, Elizabeth; Stewart, Elizabeth; Kolker, Natali; Collart, Frank; Myler, Peter; van Belle, Gerald; Kolker, Eugene
2011-01-01
High-throughput (HTP) proteomics studies generate large amounts of data. Interpretation of these data requires effective approaches to distinguish noise from biological signal, particularly as instrument and computational capacity increase and studies become more complex. Resolving this issue requires validated and reproducible methods and models, which in turn requires complex experimental and computational standards. The absence of appropriate standards and data sets for validating experimental and computational workflows hinders the development of HTP proteomics methods. Most protein standards are simple mixtures of proteins or peptides, or undercharacterized reference standards in which the identity and concentration of the constituent proteins is unknown. The Seattle Children's 200 (SC-200) proposed proteomics standard mixture is the next step toward developing realistic, fully characterized HTP proteomics standards. The SC-200 exhibits a unique modular design to extend its functionality, and consists of 200 proteins of known identities and molar concentrations from 6 microbial genomes, distributed into 10 molar concentration tiers spanning a 1,000-fold range. We describe the SC-200's design, potential uses, and initial characterization. We identified 84% of SC-200 proteins with an LTQ-Orbitrap and 65% with an LTQ-Velos (false discovery rate = 1% for both). There were obvious trends in success rate, sequence coverage, and spectral counts with protein concentration; however, protein identification, sequence coverage, and spectral counts vary greatly within concentration levels.
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Requests for Help in a Multilingual Professional Environment Testimonies and Actantial Models
Directory of Open Access Journals (Sweden)
Lejot Eve
2017-12-01
Full Text Available Professional multilingual environments using English as a lingua franca are prone to imbalances in communication, linguistic insecurity and rising tension. Non-native English speakers develop avoidance strategies in order to lessen their apprehension. To overcome these imbalances, this research aims to understand the relationships formed around languages focusing on the dynamics of integration and the requests for help. Guided by the actantial models of Greimas (1966, this qualitative study employs semiolinguistics and discourse analysis, including 19 narrative interviews with employees of Airbus and UNESCO in Hamburg, Germany in 2013. This methodology draws on actors connected through relationships of power and/or collaboration. The actantial models applied seek linguistic input through designational paradigms, shifters and modal occurrences. The actantial models illustrate how a good language competence provides a better understanding of one’s direct as well as passive environment. The learning process is shown to be a conduit to integration. The actantial model and discourse analysis shed light on the complex situation of multilingual communication settings by highlighting the influence of individuals’ linguistic skills. As a matter of fact, depending on the role of each individual in a given situation, lending a helping hand sometimes equates to upsetting the balance.
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The importance of international cooperation
CSIR Research Space (South Africa)
NASR, Jean-Marc
2017-01-01
Full Text Available Limited R&D budgets Marginal growth Increased R&T with international institutes & academia Intra-African market Center of gravity has changed Global supply sourcing Local Servicing of products Airbus Global Footprint May 2017 Airbus... 31% Europe 69% Non-Europe Other countries 11,575 (9%) Non-European Workforce 20% (in 2020) PHILOSOPHY OF INTERNATIONALIZATION Airbus Footprint in Africa May 2017 Airbus Corporate Presentation 4 Addis Ababa Nairobi Abuja Algiers Cairo...
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Acquisition and use of Orlando, Florida and Continental Airbus radar flight test data
Eide, Michael C.; Mathews, Bruce
1992-01-01
Westinghouse is developing a lookdown pulse Doppler radar for production as the sensor and processor of a forward looking hazardous windshear detection and avoidance system. A data collection prototype of that product was ready for flight testing in Orlando to encounter low level windshear in corroboration with the FAA-Terminal Doppler Weather Radar (TDWR). Airborne real-time processing and display of the hazard factor were demonstrated with TDWR facilitated intercepts and penetrations of over 80 microbursts in a three day period, including microbursts with hazard factors in excess of .16 (with 500 ft. PIREP altitude loss) and the hazard factor display at 6 n.mi. of a visually transparent ('dry') microburst with TDWR corroborated outflow reflectivities of +5 dBz. Range gated Doppler spectrum data was recorded for subsequent development and refinement of hazard factor detection and urban clutter rejection algorithms. Following Orlando, the data collection radar was supplemental type certified for in revenue service on a Continental Airlines Airbus in an automatic and non-interferring basis with its ARINC 708 radar to allow Westinghouse to confirm its understanding of commercial aircraft installation, interface realities, and urban airport clutter. A number of software upgrades, all of which were verified at the Receiver-Transmitter-Processor (RTP) hardware bench with Orlando microburst data to produce desired advanced warning hazard factor detection, included some preliminary loads with automatic (sliding window average hazard factor) detection and annunciation recording. The current (14-APR-92) configured software is free from false and/or nuisance alerts (CAUTIONS, WARNINGS, etc.) for all take-off and landing approaches, under 2500 ft. altitude to weight-on-wheels, into all encountered airports, including Newark (NJ), LAX, Denver, Houston, Cleveland, etc. Using the Orlando data collected on hazardous microbursts, Westinghouse has developed a lookdown pulse Doppler
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2010-07-01
...) Children means— (1) Persons up through age 21 who are entitled to a free public education through grade 12... 34 Education 1 2010-07-01 2010-07-01 false Definitions. 200.103 Section 200.103 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION...
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1982-09-30
catalyst for the work of this department is the Economics and Finance Council and its eight committees -- Corporate Accounting, Revenue Accounting...Fokker BV Dr. Jaap Kamp, General Manager, International Corporate Finance , Algemene Bank Nederland NV, Amsterdam, Netherlands 2:55 PM Questions 3:15...Hawkins, Vice President Finance & Taxation AIR SALE: Maidenhead, Berks William R. Pascall, Managing Director AIRBUS INDUSTRIE: New York, New York
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RAM R-200 - A Portable Ruggedized Radiation Monitoring System
International Nuclear Information System (INIS)
Wengrowicz, U.; Mazor, T.; Assido, H.; Kadmon, Y.; Tirosh, D.; Shani, G.
1999-01-01
RAM R-200, a new generation of ruggedized portable radiation-monitoring systems, is presented. The system which is a result of interdisciplinary research, was developed at the NRCN in collaboration with Ben-Gurion University. It consists of RAM R-200 - a portable radiation meter, and a variety of external probes for wide range gamma radiation fields and beta-gamma contamination detection and measurement. The meter or each one of the external probes can be used as a portable system or a stand-alone radiation measurement station. All the system's components were specially designed to meet severe environmental conditions
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19 CFR 200.735-103 - Counseling service.
2010-04-01
... 19 Customs Duties 3 2010-04-01 2010-04-01 false Counseling service. 200.735-103 Section 200.735-103 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT General Provisions § 200.735-103 Counseling service. (a) The Chairman shall appoint a Designated Agency...
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Spaulding, A. P., Jr.
1979-01-01
The preliminary design criteria of the MP1-200 wind turbine are given along with a brief description of the wind turbine generator. Performance and operational experience and cost factors are included. Recommendations for additional research are listed.
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2014-12-01
Local Economic Impact of UH-72A Manufacture ................42 viii e. EADS’ (Now Airbus Group’s) Suppliers and Subcontractors...Headquarters, Department of the Army IFR instrument flight rules IOTE initial operational test and evaluation IR infrared KO contracting officer kt...instrument flight rules ( IFR ) and visual flight rules (VFR) capabilities, thereby allowing flight at night and under low visibility weather
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2010-07-01
... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Application. 28.200 Section 28.200 Money and Finance: Treasury Office of the Secretary of the Treasury NONDISCRIMINATION ON THE BASIS OF... Application. Except as provided in §§ 28.205 through 28.235(a), these Title IX regulations apply to every...
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24 CFR 200.73 - Property development.
2010-04-01
... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Property development. 200.73 Section 200.73 Housing and Urban Development Regulations Relating to Housing and Urban Development... Continuing Eligibility Requirements for Existing Projects Property Requirements § 200.73 Property development...
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A Review of Subsurface Behavior of Plutonium and Americium at the 200-PW-1/3/6 Operable Units
Energy Technology Data Exchange (ETDEWEB)
Cantrell, Kirk J.; Riley, Robert G.
2008-01-31
This report begins with a brief summary of the history and current status of 200-PW-1/3/6 OUs in section 2.0. This is followed by a description of our concentual model of Pu/Am migration at the 200-PW-1/3/6 OUs, during both past artificial recharge conditions and current natural recharge condictions (section 3.0). Section 4.0 discusses data gaps and information needs. The final section (section 5.0) provides recommendations for futher work to address the data gaps and information needs identified in section 4.0.
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A Review of Subsurface Behavior of Plutonium and Americium at the 200-PW-1/3/6 Operable Units
International Nuclear Information System (INIS)
Cantrell, Kirk J.; Riley, Robert G.
2008-01-01
This report begins with a brief summary of the history and current status of 200-PW-1/3/6 OUs in section 2.0. This is followed by a description of our conceptual model of Pu/Am migration at the 200-PW-1/3/6 OUs, during both past artificial recharge conditions and current natural recharge conditions (section 3.0). Section 4.0 discusses data gaps and information needs. The final section (section 5.0) provides recommendations for further work to address the data gaps and information needs identified in section 4.0
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7 CFR 948.200 - Accounting and collections.
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Accounting and collections. 948.200 Section 948.200 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Accounting and Collections § 948.200 Accounting and collections. (a) Each handler's assessment account with...
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17 CFR 200.735-16 - Delegation.
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Delegation. 200.735-16 Section 200.735-16 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT... Former Members and Employees of the Commission § 200.735-16 Delegation. Any official responsibility...
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7 CFR 3052.200 - Audit requirements.
2010-01-01
... 7 Agriculture 15 2010-01-01 2010-01-01 false Audit requirements. 3052.200 Section 3052.200 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Audits § 3052.200...
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36 CFR 200.2 - Field organization.
2010-07-01
... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Field organization. 200.2 Section 200.2 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE ORGANIZATION, FUNCTIONS, AND PROCEDURES Organization § 200.2 Field organization. The field organization of the Forest...
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1997-1998 Annual Review of the 200 West and 200 East area performance assessments
International Nuclear Information System (INIS)
WOOD, M.I.
1999-01-01
An annual review of the 200 West and 200 East Area Performance Assessment (PA) analyses for fiscal year 1998 was completed. Burial ground disposal operations were found to be compliant with performance objectives in DOE Order 5820.2A. Other newly generated information and analyses relevant to PA assumptions and results were summarized. This report was initially submitted to the Department of Energy-Richland Office (DOE-RL) as a letter report in October, 1998
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42 CFR 403.200 - Basis and scope.
2010-10-01
... 42 Public Health 2 2010-10-01 2010-10-01 false Basis and scope. 403.200 Section 403.200 Public... PROVISIONS SPECIAL PROGRAMS AND PROJECTS Medicare Supplemental Policies § 403.200 Basis and scope. (a... intent of that section is to enable Medicare beneficiaries to identify Medicare supplemental policies...
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46 CFR 180.200 - Survival craft-general.
2010-10-01
... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft-general. 180.200 Section 180.200 Shipping...) LIFESAVING EQUIPMENT AND ARRANGEMENTS Number and Type of Survival Craft § 180.200 Survival craft—general. (a) Each survival craft required on a vessel by this part must meet one of the following: (1) For an...
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12 CFR 563.200 - Conflicts of interest.
2010-01-01
... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Conflicts of interest. 563.200 Section 563.200...-OPERATIONS Reporting and Bonding § 563.200 Conflicts of interest. If you are a director, officer, or employee..., or those of others with whom you have a personal or business relationship, at the expense of the...
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19 CFR 200.735-104a - Proscribed actions.
2010-04-01
... independence or impartiality; (e) Making a Government decision outside official channels; or (f) Affecting...-104a Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION EMPLOYEE RESPONSIBILITIES AND CONDUCT Provisions Governing Ethical and Other Conduct and Responsibilities of Employees § 200.735-104a Proscribed...
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21 CFR 73.200 - Synthetic iron oxide.
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Synthetic iron oxide. 73.200 Section 73.200 Food... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.200 Synthetic iron oxide. (a) Identity. (1) The color additive synthetic iron oxide consists of any one or any combination of synthetically prepared...
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Economic analysis of process steam and electricity generation by a 200 MW NHR
International Nuclear Information System (INIS)
Tian Li; Wang Yongqing
2000-01-01
New applications for low temperature nuclear heating reactors should be developed using economic analysis. This paper compares and analyzes the economics of the generation 1.5 MPa process steam and electricity by a 200 MW nuclear heating reactor (NHR-200) for industrial development. The project is very attractive economically with an internal rate of return of 19.61%, a net present worth (discount rate 10%) of 765 million yuan RMB and a capital recovery or payback period of about 5 years after construction is completed. Compared with only using the NHR-200 for in winter heating, the economic of process steam and electricity generation by NHR-200 are much better. In addition, the NHR-200 will significantly improve environmental pollution in cities and reduce the transport of coal from north to south in China
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Summary of the 200x200 GeV μ+-μ- collider working group
International Nuclear Information System (INIS)
Neuffer, D.; Whittum, D.; Bombade, P.; Cline, D.; Jackson, G.; McIntyre, P.; Peters, G.; Sasaki, M.; Summers, D.; Yokoya, K.
1996-01-01
We report the discussions and some preliminary results from the sessions of the 200x200 GeV μ + -μ - Collider working group. The physics motivation for such a open-quote open-quote medium-energy close-quote close-quote collider is discussed. Possible parameters for such a system are described, and compared with higher-energy systems. Relatively-high luminosities (L∼10 33 cm -2 s -1 ) appear possible. Modifications of existing facilities to obtain medium-energy μ + -μ - collisions are discussed. Other discussion topics (μ-p colliders, low-energy μ sources, etc.) are summarized. copyright 1995 American Institute of Physics
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Energy Technology Data Exchange (ETDEWEB)
Gris, Ph [CEA Saclay, 91 - Gif-sur-Yvette (France). Dept. d` Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l` Instrumentation Associee; [Paris-6 Univ., 75 (France)
1998-05-01
This thesis is devoted to the study of some supersymmetric quarks such as s-top and s-bottom. This investigation field is all the more interesting since the weak mass of these squarks could be explained by the strong Yukawa coupling between top and bottom quarks. The theoretical framework is defined and the insufficiency of the standard model is highlighted. Different models such as MSSM, supergravity models in which supersymmetry is a global symmetry are described. Squark phenomenology at LEP200 is exposed and the most likely disintegration channels for stop and s-bottom quarks are investigated in various models (MSSM, mSUGRA, supergravity models with light gravitino). The experimental tool used in this work, DELPHI detector is presented, the main elements involved in the search for squarks are precisely described. The last part of this thesis is dedicated to the effective search for squarks, the analysis deals with the energies: {radical}s=161, 172 and 183 GeV for which the luminosity values collected by DELPHI are respectively 9.7, 10 and 54 pb{sup -1}. The results are interpreted within the frameworks of different supersymmetric theories 184 refs.
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Netikul, Thidarat; Kiratisin, Pattarachai
2015-01-01
Carbapenem-resistant Enterobacteriaceae (CRE) has increasingly spread worldwide in the past decade. The prevalence and characteristics of CRE in Thailand are unknown. In this study, we conducted a 2-year surveillance of CRE among 12,741 clinical isolates of Enterobacteriaceae at the largest university hospital in Thailand with molecular characterization of beta-lactamase (bla) genes, including carbapenemase genes. The CRE prevalence was 1.4%. blaKPC-13 and blaIMP-14a were the only carbapenemase genes detected among these CRE isolates. blaKPC-13 gene was found in a single isolate of Escherichia coli, Enterobacter cloacae and Citrobacter freundii, and blaIMP-14a was found in four isolates of Klebsiella pneumoniae. Carbapenem-resistant K. pneumoniae (CRKP) isolates were resistant to multiple carbapenems at a higher ratio than other CRE species, and thus were further characterized for resistance phenotypes, bla genotypes and molecular epidemiology. Most CRKP isolates harboured multiple bla genes, especially those related to extended-spectrum beta-lactamases. Seven CRKP isolates were resistant to all tested carbapenems, and showed decreased ompK35 and/or ompK36 porin gene expression. Molecular typing of CRKP based on pulsed-field gel electrophoresis (PFGE) demonstrated several unrelated clones. Multilocus sequence typing (MLST) was partially concordant with PFGE results and revealed that ST340, a member of drug-resistant K. pneumoniae clonal complex 258, was the most predominant clone, followed by ST48, ST11 and ST273. The novel ST1645 was identified from this study. ST340 has neither been shown to be predominated among CRKP from other studies, nor been reported in Thailand. Therefore, it emphases a critical concern to monitor and control the spread of CRKP. PMID:26407326
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Irizar, J.; Gulde, S.; Skegg, M.; Levillain, Y.; Weber, H.
2017-09-01
Sentinel 4 is an imaging UVN (UV-VIS-NIR) dispersive spectrometer, developed by Airbus DS under an ESA contract in the frame of the joint EU/ESA COPERNICUS program. The instrument is introduced in a dedicated presentation in this conference.
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21 CFR 137.200 - Whole wheat flour.
2010-04-01
... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Whole wheat flour. 137.200 Section 137.200 Food... Flours and Related Products § 137.200 Whole wheat flour. (a) Whole wheat flour, graham flour, entire wheat flour is the food prepared by so grinding cleaned wheat, other than durum wheat and red durum...
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Comparison of the Nellcor N-200 and N-3000 pulse oximeters during simulated postoperative activities
DEFF Research Database (Denmark)
Lie, C; Kehlet, H; Rosenberg, J
1997-01-01
Twenty-six healthy volunteers were monitored simultaneously with the Nellcor N-200 and N-3000 pulse oximeters during nonhypoxaemic simulated postoperative activity. The overall number of registered events (hypoxaemic episodes or loss of signal) was fewer with the N-3000 than with the N-200 (8 vs...... to loss of signal were significantly rarer with the N-3000 than with the N-200 (3 vs. 13, p = 0.001). The Nellcor N-3000 oximeter may offer an advantage over the N-200 model when monitoring patients in the postoperative period....
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17 CFR 200.505 - Original classification.
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Original classification. 200... Information and Material § 200.505 Original classification. (a) No Commission Member or employee has the authority to classify any information on an original basis. (b) If a Commission employee originates...
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2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Employment. 200.640 Section... Programs or Activities Conducted by the Securities and Exchange Commission § 200.640 Employment. No... employment under any program or activity conducted by the agency. The definitions, requirements, and...
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The ρ radiative decay width: A measurement at 200 GeV
International Nuclear Information System (INIS)
Capraro, L.; Levy, P.; Querrou, M.; Hecke, B. van; Verbeken, M.; Amendolia, S.R.; Batignani, G.; Bedeschi, A.; Bellamy, E.H.; Bertolucci, E.; Bosisio, L.; Bottigli, U.; Bradaschia, C.; Fidecaro, F.; Foa, L.; Focardi, E.; Giannetti, P.; Giorgi, M.A.; Marrocchesi, P.S.; Menzione, A.; Ristori, L.; Scribano, A.; Stefanini, A.; Tonelli, G.; Beck, G.A.; Bologna, G.; D'Ettorre Piazzoli, B.; Mannocchi, G.; Picchi, P.; Istituto Nazionale di Fisica Nucleare, Frascati; Budinich, M.; Liello, F.; Paver, N.; Rolandi, L.; Green, M.G.; March, P.V.; Landon, M.P.J.; Strong, J.A.; Tenchini, R.
1987-01-01
The ρ - radiative decay width has been measured by studying the production of ρ - via the Primakoff effect by 200 GeV incident π - on Cu and Pb targets. This width was obtained by fitting the measured dσ/dt for ρ production with the theoretical coherent differential cross section including both the electromagnetic and strong contributions. The measured radiative width value is 81±4±4 keV: it is consistent with the ratio Γ(ρ → πγ)/Γ(ω → πγ) ∝ 1/9 as expected from the vector dominance and the quark model. (orig.)
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YU, Lianchao; GU, Limeng; BI, Qian
2015-01-01
Using the survey data on 340 farmers in Chongqing City, this paper performs an empirical analysis of the factors influencing the non-point source pollution of pesticides. The results show that the older householders will apply more pesticides, which may be due to the weak physical strength and weak ability to accept the concept of advanced cultivation; the householders with high level of education will choose to use less pesticides; the pesticide application rate is negatively correlated with...
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2010-07-01
....200 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION OIL OR HAZARDOUS MATERIAL POLLUTION PREVENTION REGULATIONS FOR VESSELS Vessel Equipment § 155.200... outside the Boundary Lines, as defined in 46 CFR part 7, in any ocean or the Gulf of Mexico; any tank...
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Analysis of neutron dose rates on RGTT200K core using MCNP5
International Nuclear Information System (INIS)
Suwoto; Zuhair
2016-01-01
The conceptual design of RGTT200K (High Temperature Gas-cooled Reactor of 200 MWth Cogeneration) is the non-annular cylindrical reactor core with TRISO kernel coated fuel particles in the form of balls called pebble and cooled by helium gas. The RGTT200K reactor core design adopts high temperature gas cooled reactor (HTGR) technology with inherent passive safety. The RGTT200K spherical fuel called pebble fuel containing thousand of TRISO-coated fuel particles of uranium oxide (UO 2 ) 10 % enriched. TRISO coating comprises four layers, namely: porous carbon buffer layer, inner pyrolytic carbon layer (IPyC, Inner Pyrolytic Carbon), silicon carbide layer (SiC) and a layer of pyrolytic carbon outer portion (OPyC, Outer Pyrolytic Carbon). Modeling and analysis of preliminary calculation of neutron dose rate on normal operating temperature (T kernel =1200K) and accident temperature (T kernel =1800K) of the RGTT200K core were performed using Monte Carlo MCNP5v1.2 code. The continuous energy nuclear data cross-sections was taken from ENDF/B-VII, JENDL-4 and JEFF-3.1 nuclear data files . Double heterogeneity model in TRISO-coated fuel particles kernel and the pebble of RGTT200K core. By utilizing EGS99304 code, the 640 amount of energy group structures (SAND-II neutron group structures) is used in the neutron fluxes and spectrum calculation in RGTT200K reactor. The RGTT200K reactor core is divided into 25 zones (5 zones in radial and 10 zones in axial directions), while the modeling of radiation and biological shielding reactor RGTT200K are used to determine of preliminary neutron dose rate emitted by the neutron source with tally cards are available in the MCNP5v1.2 code. The calculation result analyses of the neutron dose rate distributions are determined using a conversion factor of flux-to-dose taken from International Commission on Radiological Protection, ICRP. The preliminary calculations result show that the neutrons dose rate using ICRP-74 conversion factor for
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International Nuclear Information System (INIS)
Cauvin, B.; Jared, R.C.; Russo, P.; Schmitt, R.P.; Babinet, R.; Moretto, L.G.
1978-01-01
Deep inelastic fragments from the reaction sup(nat)Ag+340MeV 40 Ar have been studied in coincidence. Charged particles (10<=Z<=32) were detected and indentified in Z by means of a ΔE-E telescope, while the complementary fragments were detected in a one-dimensional solid-state position-sensitive detector. Both in-plane and out-of-plane correlations were measured. The results confirm the binary nature of the deep inelastic process for this reaction. From the measured energies and angles of the fragments and the atomic number of one of the fragments, it was possible to determine the total mass loss due to the de-excitation of the fragments as well as the total evaporated charge at symmetry. An iterative procedure is discussed which enables one to determine the masses and kinetic energies of the fragments before evaporation, as well as the total number of particles evaporated by each fragment. The widths of the in-plane and out-of-plane correlations agree with the results of the iterative calculations, as do evaporation calculations which are based on the charge equilibrium model. The experimental results support the charge equilibrium model and indicate that thermal equilibrium is achieved between the fragments at fixed mass asymmetry. (Auth.)
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17 CFR 200.71 - Fiduciary relationships.
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Fiduciary relationships. 200...; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.71 Fiduciary relationships. A... are involved in questions to be determined by him. Such relationships would include trustees...
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14 CFR 1251.200 - Discrimination prohibited.
2010-01-01
... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Discrimination prohibited. 1251.200 Section... OF HANDICAP Employment Practices § 1251.200 Discrimination prohibited. (a) General. (1) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment under any...
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Fluctuations of multiplicities in rapidity windows in sulphur-sulphur collisions at 200 A GeV
Bächler, J; Runge, K; Schmoetten, E; Bartke, Jerzy; Gladysz-Dziadus, E; Kowalski, M; Stefanski, P; Bialkowska, H; Böck, R K; Brockmann, R; Sandoval, A; Buncic, P; Ferenc, D; Kadija, K; Ljubicic, A; Vranic, D; Chase, S I; Harris, J W; Odyniec, Grazyna Janina; Pugh, Howel G; Rai, G; Teitelbaum, L; Tonse, S R; Derado, I; Eckardt, V; Gebauer, H J; Rauch, W; Schmitz, N; Seyboth, P; Seyerlein, J; Vesztergombi, G; Eschke, J; Heck, W; Kabana, S; Kühmichel, A; Lahanas, L; Lee, Y; Le Vine, M J; Margetis, S; Renfordt, R E; Röhrich, D; Rothard, H; Schmidt, E; Schneider, I; Stock, Reinhard; Ströbele, H; Wenig, S; Fleischmann, B; Fuchs, M; Gazdzicki, M; Kosiec, J; Skrzypczak, E; Keidel, R; Piper, A; Pühlhofer, F; Nappi, E; Posa, F; Paic, G; Panagiotou, A D; Petridis, A; Vasileiadis, G; Pfennig, J
1992-01-01
Multiplicity distributions and their second moments fornegatively charged particles produced in32S-S central and minimum bias interactions at 200A GeV are studied in various rapidity intervals. Fritiof and Venus models mostly describe the dependence of second moments on rapidity intervals in minimum bias interactions, but not in central collisions. For central collisions the behaviour of second moments might indicate enhanced multiplicity fluctuations.
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RCRA facility investigation report for the 200-PO-1 operable unit. Revision 1
International Nuclear Information System (INIS)
1997-05-01
This Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) report is prepared in support of the RFI/corrective measures study process for the 200-PO-1 Groundwater Operable Unit in the 200 East Area of the Hanford Site. This report summarizes existing information on this operable unit presented in the 200 East and PUREX Aggregate Area Management Study Reports, contaminant specific studies, available modeling data, and groundwater monitoring data summary reports. Existing contaminant data are screened against current regulatory limits to determine contaminants of potential concern (COPC). Each identified COPC is evaluated using well-specific and plume trend analyses
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Experimental charge fractions of hydrogen scattered from insulators at 50-340 keV
Ross, Graham G
2002-01-01
Ion bombardment of insulators induces accumulation of electric charges at and under the insulator surfaces. This paper deals with the effect of the accumulated electric charges on the charge fractions of scattered hydrogen. We have measured and compiled charge fractions of hydrogen, in the energy range (for the scattered particles) from 50 to 340 keV, scattered from polystyrene, polymethylmethacrylate, polycarbonate, polyethylene and silicon. In order to establish the effect of the charge accumulation, some samples have been cut from a thick (1 mm) sheet, while some others have been spin coated (approx 250 nm) onto silicon wafers. Experimental measurements have been fitted with the equation f(0)=Aexp(-V sup 2 /V sub i V sub 0), where f(0) is the neutral fraction, V the velocity, V sub i the 'Bohr velocity' for the electron of projectiles, A and V sub 0 the fitting parameters. Comparisons using the least-square fitting procedure have shown that the accumulation of electric charges on the thick polymer samples ...
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Characterization and decant of Tank 42H sludge sample ESP-200
International Nuclear Information System (INIS)
Hay, M.S.
2000-01-01
DWPF Engineering requested that the Savannah River Technology Center (SRTC) provide a demonstration of the DWPF flowsheet on sludge from Tank 42H in the Shielded Cell facility. A 5 liter sample of the Tank 42H sludge (ESP-200), obtained with the tank contents fully mixed, arrived at SRTC on January 20, 1998. This report details receipt of the 5 liter sample at SRTC, the decant of the sample, and the characterization of the pre- and post-decant Tank 42H sludge. Evaluation of the measured composition of the supernate indicates Sample ESP-200 became diluted approximately 20 percent by volume prior to receipt. This dilution complicates the relationship of the characterization of Post-Decant ESP-200 to the current contents of Tank 42H. For the purposes of modeling the current tank contents of Tank 42H, this report provides an estimated composition based on analytical data of recent samples from Tank 42H
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Characterization and decant of Tank 42H sludge sample ESP-200
Energy Technology Data Exchange (ETDEWEB)
Hay, M.S.
2000-04-25
DWPF Engineering requested that the Savannah River Technology Center (SRTC) provide a demonstration of the DWPF flowsheet on sludge from Tank 42H in the Shielded Cell facility. A 5 liter sample of the Tank 42H sludge (ESP-200), obtained with the tank contents fully mixed, arrived at SRTC on January 20, 1998. This report details receipt of the 5 liter sample at SRTC, the decant of the sample, and the characterization of the pre- and post-decant Tank 42H sludge. Evaluation of the measured composition of the supernate indicates Sample ESP-200 became diluted approximately 20 percent by volume prior to receipt. This dilution complicates the relationship of the characterization of Post-Decant ESP-200 to the current contents of Tank 42H. For the purposes of modeling the current tank contents of Tank 42H, this report provides an estimated composition based on analytical data of recent samples from Tank 42H.
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200-BP-5 operable unit treatability test report
Energy Technology Data Exchange (ETDEWEB)
NONE
1996-04-01
The 200-BP-5 Operable Unit was established in response to recommendations presented in the 200 East Groundwater Aggregate Area Management Study Report (AAMSR) (DOE-RL 1993a). Recognizing different approaches to remediation, the groundwater AAMSR recommended separating groundwater from source and vadose zone operable units and subdividing 200 East Area groundwater into two operable units. The division between the 200-BP-5 and 200-PO-1 Operable Units was based principally on source operable unit boundaries and distribution of groundwater plumes derived from either B Plant or Plutonium/Uranium Extraction (PUREX) Plant liquid waste disposal sites.
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200-BP-5 operable unit treatability test report
International Nuclear Information System (INIS)
1996-04-01
The 200-BP-5 Operable Unit was established in response to recommendations presented in the 200 East Groundwater Aggregate Area Management Study Report (AAMSR) (DOE-RL 1993a). Recognizing different approaches to remediation, the groundwater AAMSR recommended separating groundwater from source and vadose zone operable units and subdividing 200 East Area groundwater into two operable units. The division between the 200-BP-5 and 200-PO-1 Operable Units was based principally on source operable unit boundaries and distribution of groundwater plumes derived from either B Plant or Plutonium/Uranium Extraction (PUREX) Plant liquid waste disposal sites
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Time-dependent Bloch-Maxwell modelling of 1 mJ, 200 fs seeded soft x-ray laser
International Nuclear Information System (INIS)
Zeitoun, Ph.; Oliva, E.; Fajardo, M.; Velarde, P.; Ros, D.; Sebban, S.
2010-01-01
Complete text of publication follows. Seeding of high harmonic generation in a soft x-ray plasma amplifier has been first proposed and tested by T. Ditmire and collaborators. The experiment demonstrated low amplification (*2), with a very strong background coming from the soft x-ray laser ASE. Later seeding experiments reached very high amplification factors (up to 600) in both gas (Ph. Zeitoun et al.) and solid amplifiers (Wang et at.). Surprisingly, solid amplifiers extracted less energy (90 nJ) than gas amplifier (∼ 1 μJ) with equivalent pump energy. We recently demonstrated that 50-100 μJ is achievable with adequate plasma tailoring. However, this energy is still low as compared to the 10 mJ per pulse demonstrated on the ASE soft x-ray laser running at PALS facility (Czech Republic). In order to model the seeding process of PALS soft x-ray laser, we developed a time-dependent Bloch-Maxwell model that solves coherently the pumping, amplification and saturation processes. We demonstrated that direct seeding, with femtosecond pulse, a soft x-ray plasma amplifier having gain duration of several 100s of picosecond cannot extract the stored energy keeping the output beam energy in the 100 μJ range. We proposed and fully modelled a new seeding scheme that allows to achieve 10 mJ, 200 fs soft x-ray laser.
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12 CFR 550.200 - Must I review a prospective account before I accept it?
2010-01-01
... accept it? 550.200 Section 550.200 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE... § 550.200 Must I review a prospective account before I accept it? Before accepting a prospective fiduciary account, you must review it to determine whether you can properly administer the account. ...
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2010-10-01
... time during which fuel tanks are exposed to flammable conditions is one of these criteria. The other... flammable fuel vapors, could result in fuel tank explosions and consequent loss of the airplane. [[Page... information and, in general, agree with their substance. But we might have found it necessary to use different...
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Design and analysis of Helium Brayton cycle for energy conversion system of RGTT200K
International Nuclear Information System (INIS)
Ignatius Djoko Irianto
2016-01-01
The helium Brayton cycle for the design of cogeneration energy conversion system for RGTT200K have been analyzed to obtain the higher thermal efficiency and energy utilization factor. The aim of this research is to analyze the potential of the helium Brayton cycle to be implemented in the design of cogeneration energy conversion system of RGTT200K. Three configuration models of cogeneration energy conversion systems have been investigated. In the first configuration model, an intermediate heat exchanger (IHX) is installed in series with the gas turbine, while in the second configuration model, IHX and gas turbines are installed in parallel. The third configuration model is similar to the first configuration, but with two compressors. Performance analysis of Brayton cycle used for cogeneration energy conversion system of RGTT200K has been done by simulating and calculating using CHEMCAD code. The simulation result shows that the three configuration models of cogeneration energy conversion system give the temperature of thermal energy in the secondary side of IHX more than 800 °C at the reactor coolant mass flow rate of 145 kg/s. Nevertheless, the performance parameters, which include thermal efficiency and energy utilization factor (EUF), are different for each configuration model. By comparing the performance parameter in the three configurations of helium Brayton cycle for cogeneration energy conversion systems RGTT200K, it is found that the energy conversion system with a first configuration has the highest thermal efficiency and energy utilization factor (EUF). Thermal efficiency and energy utilization factor for the first configuration of the reactor coolant mass flow rate of 145 kg/s are 35.82 % and 80.63 %. (author)
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17 CFR 200.70 - Business promotions.
2010-04-01
... AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.70 Business promotions. A member must not engage in any other business, employment or vocation while in office, nor may he ever use the... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Business promotions. 200.70...
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45 CFR 604.200 - Agency and legislative liaison.
2010-10-01
... 45 Public Welfare 3 2010-10-01 2010-10-01 false Agency and legislative liaison. 604.200 Section 604.200 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NEW RESTRICTIONS ON LOBBYING Activities by Own Employees § 604.200 Agency and legislative liaison. (a...
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34 CFR 200.6 - Inclusion of all students.
2010-07-01
... 34 Education 1 2010-07-01 2010-07-01 false Inclusion of all students. 200.6 Section 200.6... Basic Programs Operated by Local Educational Agencies Standards and Assessments § 200.6 Inclusion of all...— (A) For each student with a disability, as defined under section 602(3) of the IDEA, appropriate...
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24 CFR 92.200 - Private-public partnership.
2010-04-01
... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Private-public partnership. 92.200 Section 92.200 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development HOME INVESTMENT PARTNERSHIPS PROGRAM Program Requirements § 92.200 Private-public partnership...
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24 CFR 200.36 - Financial reporting requirements.
2010-04-01
... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Financial reporting requirements. 200.36 Section 200.36 Housing and Urban Development Regulations Relating to Housing and Urban... Regulations § 200.36 Financial reporting requirements. The mortgagor must comply with the financial reporting...
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17 CFR 200.735-7 - Negotiation for employment.
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Negotiation for employment. 200.735-7 Section 200.735-7 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Employees and Former Members and Employees of the Commission § 200.735-7 Negotiation for employment. (a) An...
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Simulation Models of Search in the Presence of Decoys
1972-04-01
it. Wl It Ie Ile’ rad i tt.s of’ th acca i1,Nn;’u h mputicciýl cia IpAc’M1nteLI I Ii’ I IaS 11(:11Z I Iv Ihelli toigte vi lice of 200( cmin FoId ret 21...nr IF( T ND. F 0) r-0 50 "Ŕ n 3p’c I. CALL XYNOV( TN, DT, V,XL. AS, YLASI, COU 0 C, AL,",I, h, P 303 ’+ X N 0 t, YN0,1 NI D, ANO ,’, I AN’) 00 F5
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45 CFR 149.200 - Use of reimbursements.
2010-10-01
... 45 Public Welfare 1 2010-10-01 2010-10-01 false Use of reimbursements. 149.200 Section 149.200 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Use of Reimbursements § 149.200 Use of reimbursements...
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Liu, Tongxu; Li, Xiaomin; Li, Fangbai; Han, Rui; Wu, Yundang; Yuan, Xiu; Wang, Ying
2016-07-01
Although c-type cytochromes (c-Cyts) mediating metal reduction have been mainly investigated with in vitro purified proteins of dissimilatory metal reducing bacteria, the in vivo behavior of c-Cyts is still unclear given the difficulty in measuring the proteins of intact cells. Here, c-Cyts in living Shewanella putrefaciens 200 (SP200) was successfully quantified using diffuse-transmission UV/Vis spectroscopy due to the strong absorbance of hemes, and the in situ spectral kinetics of Cr(VI) reduction by c-Cyts were examined over time. The reduced product Cr(III) observed on the cell surface may play a role in inhibiting the Cr(VI) reduction and reducing the cell numbers with high concentrations (>200 μM) of Cr(VI) evidenced by the 16S rRNA analysis. A brief kinetic model was established with two predominant reactions, redox transformation of c-Cyts and Cr(VI) reduction by reduced c-Cyts, but the fitting curves were not well-matched with c-Cyts data. The Cr(III)-induced inhibitory effect to the cellular function of redox transformation of c-Cyts was then added to the model, resulting in substantially improved the model fitting. This study provides a case of directly examining the reaction properties of outer-membrane enzyme during microbial metal reduction processes under physiological conditions.
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9 CFR 201.200 - Sale of livestock to a packer on credit.
2010-01-01
... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Sale of livestock to a packer on credit. 201.200 Section 201.200 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS... credit to ________, a packer, and I understand that in doing so I will have no rights under the trust...
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Main design and safety features of a 200MW nuclear heating reactor
International Nuclear Information System (INIS)
Zheng, Wenxiang; Gao, Zuying; Wang, Dazhong
1992-01-01
Inept has been in charge of the development of a nuclear heating reactor since 1980s, which is one of the national key R and D Programs in China. A 5MWt experimental NCR was completed at Inept in 1989 and has operated successfully for space heating since then. In order to realize the commercialization of the NCR, it has been decided to construct a 200MW demonstration NCR in 1993. A number of advanced features, including natural circulation, integrated arrangement, self-pressurized performance, dual vessel structure, hydraulic control rod drive and passive safety systems, have been incorporated into the NCR-200 to achieve its safety goal and economic viability. This makes the NCR safe, simple, reliable, easy-constructed and maintained. At present, the design work of the NCR-200 have shown that its safety characteristics are excellent. The NCR could play an important role in resolving future energy and environmental problems in China. The paper will mainly cover the key design considerations, main technical features and safety analysis results of the NCR-200
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41 CFR 102-117.200 - What is HAZMAT?
2010-07-01
... Shipping Hazardous Material (HAZMAT) § 102-117.200 What is HAZMAT? HAZMAT is a substance or material the... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is HAZMAT? 102-117.200 Section 102-117.200 Public Contracts and Property Management Federal Property Management...
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34 CFR 200.12 - Single State accountability system.
2010-07-01
... 34 Education 1 2010-07-01 2010-07-01 false Single State accountability system. 200.12 Section 200... Improving Basic Programs Operated by Local Educational Agencies State Accountability System § 200.12 Single State accountability system. (a)(1) Each State must demonstrate in its State plan that the State has...
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29 CFR 2530.200b-6 - Maritime industry.
2010-07-01
... 29 Labor 9 2010-07-01 2010-07-01 false Maritime industry. 2530.200b-6 Section 2530.200b-6 Labor... Provisions § 2530.200b-6 Maritime industry. (a) General. Sections 202(a)(3)(D), 203(b)(2)(D) and 204(b)(3)(E... provisions applicable to the maritime industry. In general, those provisions permit statutory standards...
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CCNA routing and switching study guide exams 100-101, 200-101, and 200-120
Lammle, Todd
2013-01-01
Prepare for the new CCNA exams with this Todd Lammle study guide Cisco author, speaker, and trainer Todd Lammle is considered the authority on all things networking, and his books have sold almost a million copies worldwide. This all-purpose CCNA study guide methodically covers all the objectives of the ICND1 (100-101) and ICND2 (200-101) exams as well as providing additional insight for those taking CCNA Composite (200-120) exam. It thoroughly examines operation of IP data networks, LAN switching technologies, IP addressing (IPv4/IPv6), IP routing technologies, IP services, network device s
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Evidence of incomplete relaxation in the reaction Ag+40Ar at 288 and 340 MeV bombarding energies
International Nuclear Information System (INIS)
Galin, J.; Moretto, L.G.; Babinet, R.; Schmitt, R.; Jared, R.; Thompson, S.G.
1975-01-01
The particles emitted in the reaction induced by 40 Ar on natural Ag at 288 and 340 MeV bombarding energy have been studied. The fragments have been identified in atomic number, their kinetic energy distribution and their angular distributions have been measured. The kinetic energy spectra show two components: a high-energy component related to the beam energy, or quasi-elastic component, and a low kinetic energy component, close to the Coulomb energy called relaxed component. The relaxed component is present at all angles and for all particles. The quasi-elastic component is present close to the grazing angle for atomic numbers close to that of the projectile. The relaxed cross section increases with atomic number for Z>9. The increase in cross section is sharper for the lower bombarding energy. The angular distributions are forward peaked, in excess of 1/sin(theta) for all the measured atomic numbers. The forward peaking is larger for particles close in Z to the projectile. The results are interpreted in terms of characteristic times associated with a short-lived intermediate complex. The cross sections and angular distributions are satisfactorily reproduced on the basis of a model accounting for a diffusion process occurring along the mass asymmetry coordinate of the intermediate complex. (Auth.)
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Ferranti, L.; Wan, Y.; Keviczky, T.
2018-01-01
This paper focuses on the longitudinal control of an Airbus passenger aircraft in the presence of elevator jamming faults. In particular, in this paper, we address permanent and temporary actuator jamming faults using a novel reconfigurable fault-tolerant predictive control design. Due to their
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Type QH-200 conveyor-belt nuclear scale
International Nuclear Information System (INIS)
Li Shuming; Dong Shiyuan; Li Furong; Wan Zemin
1991-01-01
Type QH-200 conveyor-belt nuclear scale is a reliable and on-line device that weighs solids mass flow continuously by γ-ray absorption and scattering. The operation principle and measuring method are described. And some factors influencing the accuracy are discussed. The full scale total weight of type QH-200 nuclear scale is 10 6 t. The result of calibration in the industrial field shows that the accuracy of QH-200 is better than ±1.0% for typical belt loading
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12 CFR 411.200 - Agency and legislative liaison.
2010-01-01
... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Agency and legislative liaison. 411.200 Section 411.200 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES NEW RESTRICTIONS ON LOBBYING Activities by Own Employees § 411.200 Agency and legislative liaison. (a) The prohibition on the use of...
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Hoefert, Jaimee E; Bjerke, Glen A; Wang, Dongmei; Yi, Rui
2018-06-04
The microRNA (miRNA)-200 (miR-200) family is highly expressed in epithelial cells and frequently lost in metastatic cancer. Despite intensive studies into their roles in cancer, their targets and functions in normal epithelial tissues remain unclear. Importantly, it remains unclear how the two subfamilies of the five-miRNA family, distinguished by a single nucleotide within the seed region, regulate their targets. By directly ligating miRNAs to their targeted mRNA regions, we identify numerous miR-200 targets involved in the regulation of focal adhesion, actin cytoskeleton, cell cycle, and Hippo/Yap signaling. The two subfamilies bind to largely distinct target sites, but many genes are coordinately regulated by both subfamilies. Using inducible and knockout mouse models, we show that the miR-200 family regulates cell adhesion and orientation in the hair germ, contributing to precise cell fate specification and hair morphogenesis. Our findings demonstrate that combinatorial targeting of many genes is critical for miRNA function and provide new insights into miR-200's functions. © 2018 Hoefert et al.
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17 CFR 200.506 - Derivative classification.
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Derivative classification. 200.506 Section 200.506 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Classification and Declassification of National Security...
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10 CFR 603.200 - Contracting officer responsibilities.
2010-01-01
....200 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Appropriate Use of Technology Investment Agreements § 603.200 Contracting officer responsibilities... contracting officer's judgment that the use of a TIA could benefit the RD&D objectives in ways that likely...
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The FIREBall-2 UV sample grating efficiency at 200-208nm
Quiret, S.; Milliard, B.; Grange, R.; Lemaitre, G. R.; Caillat, A.; Belhadi, M.; Cotel, A.
2014-07-01
The FIREBall-2 (Faint Intergalactic Redshifted Emission Balloon-2) is a balloon-borne ultraviolet spectro-imaging mission optimized for the study of faint diffuse emission around galaxies. A key optical component of the new spectrograph design is the high throughput cost-effective holographic 2400 ℓ =mm, 110x130mm aspherized reflective grating used in the range 200 - 208nm, near 28°deviation angle. In order to anticipate the efficiency in flight conditions, we have developed a PCGrate model for the FIREBall grating calibrated on linearly polarized measurements at 12° deviation angle in the range 240-350nm of a 50x50mm replica of the same master selected for the flight grating. This model predicts an efficiency within [64:7; 64:9]+/-0:7% (S polarization) and [38:3; 45]+/-2:2% (P-polarization) for the baseline aluminum coated grating with an Al2O3 natural oxidation layer and within [63:5; 65] +/-1% (S-polarization) and [51:3; 54:8] +/-2:8% (P-polarization) for an aluminum plus a 70nm MgF2 coating, in the range 200 - 208nm and for a 28°deviation angle. The model also shows there is room for significant improvements at shorter wavelengths, of interest for future deep UV spectroscopic missions.
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Noise Emission of a 200 kW Vertical Axis Wind Turbine
Directory of Open Access Journals (Sweden)
Erik Möllerström
2015-12-01
Full Text Available The noise emission from a vertical axis wind turbine (VAWT has been investigated. A noise measurement campaign on a 200 kW straight-bladed VAWT has been conducted, and the result has been compared to a semi-empirical model for turbulent-boundary-layer trailing edge (TBL-TE noise. The noise emission from the wind turbine was measured, at wind speed 8 m/s, 10 m above ground, to 96.2 dBA. At this wind speed, the turbine was stalling as it was run at a tip speed lower than optimal due to constructional constraints. The noise emission at a wind speed of 6 m/s, 10 m above ground was measured while operating at optimum tip speed and was found to be 94.1 dBA. A comparison with similar size horizontal axis wind turbines (HAWTs indicates a noise emission at the absolute bottom of the range. Furthermore, it is clear from the analysis that the turbulent-boundary-layer trailing-edge noise, as modeled here, is much lower than the measured levels, which suggests that other mechanisms are likely to be important, such as inflow turbulence.
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Development of a 200kW multi-fuel type PAFC power plant
Energy Technology Data Exchange (ETDEWEB)
Take, Tetsuo; Kuwata, Yutaka; Adachi, Masahito; Ogata, Tsutomu [NTT Integrated Information & Energy System Labs., Tokyo (Japan)
1996-12-31
Nippon Telegraph and Telephone Corporation (NFT) has been developing a 200 kW multi-fuel type PAFC power plant which can generate AC 200 kW of constant power by switching fuel from pipeline town gas to liquefied propane gas (LPG) and vice versa. This paper describes the outline of the demonstration test plant and test results of its fundamental characteristics.
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The development of a 200 kV monochromated field emission electron source
Energy Technology Data Exchange (ETDEWEB)
Mukai, Masaki, E-mail: mmukai@jeol.co.jp [JEOL Ltd., 3-1-2 Musashino, Akishima, Tokyo 196-8558 (Japan); Kim, Judy S. [University of Oxford, Department of Materials, Parks Road, Oxford, OX1 3PH (United Kingdom); Omoto, Kazuya; Sawada, Hidetaka; Kimura, Atsushi; Ikeda, Akihiro; Zhou, Jun; Kaneyama, Toshikatsu [JEOL Ltd., 3-1-2 Musashino, Akishima, Tokyo 196-8558 (Japan); Young, Neil P.; Warner, Jamie H.; Nellist, Peter D.; Kirkland, Angus I. [University of Oxford, Department of Materials, Parks Road, Oxford, OX1 3PH (United Kingdom)
2014-05-01
We report the development of a monochromator for an intermediate-voltage aberration-corrected electron microscope suitable for operation in both STEM and TEM imaging modes. The monochromator consists of two Wien filters with a variable energy selecting slit located between them and is located prior to the accelerator. The second filter cancels the energy dispersion produced by the first filter and after energy selection forms a round monochromated, achromatic probe at the specimen plane. The ultimate achievable energy resolution has been measured as 36 meV at 200 kV and 26 meV at 80 kV. High-resolution Annular Dark Field STEM images recorded using a monochromated probe resolve Si–Si spacings of 135.8 pm using energy spreads of 218 meV at 200 kV and 217 meV at 80 kV respectively. In TEM mode an improvement in non-linear spatial resolution to 64 pm due to the reduction in the effects of partial temporal coherence has been demonstrated using broad beam illumination with an energy spread of 134 meV at 200 kV. - Highlights: • Monochromator for 200 kV aberration corrected TEM and STEM was developed. • Monochromator produces monochromated and achromatic probe at specimen plane. • Ultimate energy resolution was measured to be 36 meV at 200 kV and 26 meV at 80 kV. • Atomic resolution STEM images were recorded using monochromated electron probe. • Improvements of TEM resolution were confirmed using monochromated illumination.
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The development of a 200 kV monochromated field emission electron source
International Nuclear Information System (INIS)
Mukai, Masaki; Kim, Judy S.; Omoto, Kazuya; Sawada, Hidetaka; Kimura, Atsushi; Ikeda, Akihiro; Zhou, Jun; Kaneyama, Toshikatsu; Young, Neil P.; Warner, Jamie H.; Nellist, Peter D.; Kirkland, Angus I.
2014-01-01
We report the development of a monochromator for an intermediate-voltage aberration-corrected electron microscope suitable for operation in both STEM and TEM imaging modes. The monochromator consists of two Wien filters with a variable energy selecting slit located between them and is located prior to the accelerator. The second filter cancels the energy dispersion produced by the first filter and after energy selection forms a round monochromated, achromatic probe at the specimen plane. The ultimate achievable energy resolution has been measured as 36 meV at 200 kV and 26 meV at 80 kV. High-resolution Annular Dark Field STEM images recorded using a monochromated probe resolve Si–Si spacings of 135.8 pm using energy spreads of 218 meV at 200 kV and 217 meV at 80 kV respectively. In TEM mode an improvement in non-linear spatial resolution to 64 pm due to the reduction in the effects of partial temporal coherence has been demonstrated using broad beam illumination with an energy spread of 134 meV at 200 kV. - Highlights: • Monochromator for 200 kV aberration corrected TEM and STEM was developed. • Monochromator produces monochromated and achromatic probe at specimen plane. • Ultimate energy resolution was measured to be 36 meV at 200 kV and 26 meV at 80 kV. • Atomic resolution STEM images were recorded using monochromated electron probe. • Improvements of TEM resolution were confirmed using monochromated illumination
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MicroRNA-200a suppresses the Wnt/β-catenin signaling pathway by interacting with β-catenin.
Su, Juan; Zhang, Anling; Shi, Zhendong; Ma, Feifei; Pu, Peiyu; Wang, Tao; Zhang, Jie; Kang, Chunsheng; Zhang, Qingyu
2012-04-01
The Wnt/β-catenin signaling pathway is crucial for human organ development and is involved in tumor progression of many cancers. Accumulating evidence suggests that the expression of β-catenin is, in part, regulated by specific microRNAs (miRNAs). The purpose of this study was to determine the expression of a recently identified epithelial to mesenchymal transition (EMT)-associated tumor suppressor microRNA (miR)-200a, in cancer cells. We also aimed to identify specific miR-200a target genes and to investigate the antitumor effects of miR-200a on the Wnt/β-catenin signaling pathway. We employed TOP/FOP flash luciferase assays to identify the effect of miR-200a on the Wnt/β-catenin pathway and we confirmed our observations using fluorescence microscopy. To determine target genes of miR-200a, a 3' untranslated region (3' UTR) luciferase assay was performed. Cell viability, invasion and wound healing assays were carried out for functional analysis after miRNA transfection. We further investigated the role of miR-200a in EMT by Western blot analysis. We found fluctuation in the expression of miR-200a that was accompanied by changes in the expression of members of the Wnt/β-catenin signaling pathway. We also determined that miR-200a can directly interact with the 3' UTR of CTNNB1 (the gene that encodes β-catenin) to suppress Wnt/β-catenin signaling. MiR-200a could also influence the biological activities of SGC790 and U251 cells. Our results demonstrate that miR-200a is a new tumor suppressor that can regulate the activity of the Wnt/β-catenin signaling pathway via two mechanisms. MiR-200a is a candidate target for tumor treatment via its regulation of the Wnt/β-catenin signaling pathway.
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ANALISIS EFEK KECELAKAAN WATER INGRESS TERHADAP REAKTIVITAS DOPPLER TERAS RGTT200K
Directory of Open Access Journals (Sweden)
Zuhair Zuhair
2015-03-01
melekat dengan cara pasif. Kata kunci: Water ingress, reaktivitas Doppler, RGTT200K In high temperature reactor, the negative temperature reactivity coefficient guarantees fission reaction in the core remain under the control and decay heat will not melt the fuel which cause the release of radioactive substances into the environment. But the entry of water (water ingress into the reactor core due to rupture of a steam generator tube heat exchanger, which is known as one of the design basis accidents, can introduce positive reactivity with other potential hazards such as graphite corrosion and damage of the reflector structure material. This paper will investigate the effect of water ingress accident on Doppler reactivity coefficient of RGTT200K core. The capability of the Doppler reactivity coefficient to compensate positive reactivity incurred during water ingress accident will be examined through a series of calculations with MCNPX code and ENDF/B-VII library for fuel temperature changes from 800K to 1800K. Three options of UO2, ThO2/UO2 and PuO2 fuel kernels with three lattice models of fuel pebble in the reactor core was applied for condition of water ingress with water density from 0 to 1000 kg/m3. The results of the calculations show that Doppler reactivity coefficient is negative for the entire fuel options being considered even for a large possibility of water ingress. The effects of water ingress becomes stronger in lattice model with lower packing fraction because more volume available for water entering the reactor core. The effect of water ingress is also stronger in the uranium core compared to thorium and plutonium cores as a consequence of the Doppler phenomenon where the neutron absorption in resonance region of 238U is greater than 232Th and 240Pu. It can be concluded overall that Doppler coefficient of RGTT200K core has capability to compensate the reactivity insertion introduced by water ingress accident. RGTT200K core with UO2, ThO2/UO2 and PuO2
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The CARIBIC flying observatory and its applications
International Nuclear Information System (INIS)
Brenninkmeijer, C.
2012-01-01
The troposphere can be considered as a complex chemical reactor reaching from the boundary layer up to the tropopause region, in which a multitude of reactions takes place driven by sunlight and supplied with precursors emitted by vegetation, wildfires, and obviously human activities on earth, like burning oil products. Research aircraft (say modified business jets) are far too expensive for a global view of this extensive atmospheric system that changes from day to night, season to season, year to year, and will keep changing. CARIBIC (www.caribic.de) is a logical answer; it is a flying observatory, a 1.5 ton freight container packed with over 15 instruments, for exploring the atmosphere on a regular basis using cargo space in a Lufthansa Airbus A340-600 on intercontinental flights. By means of various results obtained by CARIBIC, about among others volcanic eruptions, the monsoon and accompanying emissions of methane, and long range transport of pollution, we will show how some of the questions atmospheric research grapples with are being addressed, without having a fleet of business jets. (author)
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34 CFR 200.59 - Duties of paraprofessionals.
2010-07-01
...) Conducting parent involvement activities. (5) Providing instructional support in a library or media center... 34 Education 1 2010-07-01 2010-07-01 false Duties of paraprofessionals. 200.59 Section 200.59 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY...
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International Nuclear Information System (INIS)
1996-10-01
This environmental assessment has been prepared to assess potential environmental impacts associated with the US Department of Energy's proposed action: the salvage/demolition of the 200 West Area, 200 East Area, and 300 Area Steam Plants and steam distribution piping. Impact information will be used by the US Department of Energy, Richland Operations Office Manager, to determine if the proposed action is a major federal action significantly affecting the quality of the human environment. If the proposed action is determined to be major and significant, an environmental impact statement will be prepared. If the proposed action is determined not to be major and significant, a Finding of No Significant Impact (FONSI) will be issued and the action can proceed. The proposed action involves the salvage and demolition of the 200 West Area, 200 East Are, and 300 Area steam plants and their associated steam distribution piping, equipment, and ancillary facilities. Activities include the salvaging and recycling of all materials, wastes, and equipment where feasible, with waste minimization efforts utilized
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International Nuclear Information System (INIS)
Beasley, D.G.; Roberts, L.K.; Beard, J.; Stanfield, J.W.
1996-01-01
Unlike FS-type UVB sunlamps, which have a significant amount of effective immunosuppressive non-solar UV energy at wavelengths below 295 nm, the immunosuppression effectiveness spectrum of UVA-340 sunlamps was nearly identical to that of a solar simulator. The purpose of this study was to evaluate this sunlamp for conducting photoimmunological and sunscreen immune protection studies. Groups of C3H mice were exposed to a range of UVA-340 sunlamp doses (0.25 kJ/m 2 to 20.0 kJ/m 2 ) to establish a dose-response curve and determine the minimum immune suppression dose (MISD) for induction of local-type suppression of contact hypersensitivity (CH). The MISD, defined as the lowest UV dose given to produce ∼ 50% suppression of the CH response in mice, was determined to be 1.0 kJ/m 2 for UVA-340 sunlamps. Immune protection tests on four marketed sunscreen lotions (sun protection factors [SPF] 4, 8, 15 and 30) were then conducted with UVA-340 sunlamps using MISD as the endpoint. The immune protection factors for these sunscreens were equivalent to the level of protection predicted by their labeled SPF. These results are similar to those we have previously obtained using a solar simulator. (author)
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CCNA routing and switching review guide exams 100-101, 200-101, and 200-120
Lammle, Todd
2013-01-01
Todd Lammle's focused, concise review guide, updated for the latest CCNA exams CCNA is one of the most sought after certifications for IT professionals. If you're preparing for the CCNA Routing and Switching certification, this Sybex review guide offers the best quick review available. Organized by exam objective, it's the perfect supplement to other learning tools, including the Sybex CCNA Routing and Switching Study Guide (ISBN: 9781118749616). All exam topics from exams 100-101, 200-101, and 200-120 are thoroughly covered, and additional study materials including bonus exams, electronic f
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34 CFR 200.28 - Schoolwide program components.
2010-07-01
... instructional program. (c) Parental involvement. (1) A schoolwide program must involve parents in the planning... 34 Education 1 2010-07-01 2010-07-01 false Schoolwide program components. 200.28 Section 200.28 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY...
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FEASIBILITY STUDY REPORT FOR THE 200-ZP-1 GROUNDWATER OPERABLE UNIT
Energy Technology Data Exchange (ETDEWEB)
BYRNES ME
2008-07-18
, and to the extent practicable, the NCP. This FS conforms to the conditions set forth in the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) (Ecology et al. 2003) and amendments, signed by the Washington State Department of Ecology (Ecology), EPA, and DOE Richland Operations Office (RL). This also includes Tri-Party Agreement Milestone M-015-00C for completing all 200 Area non-tank farm OU pre-Record of Decision (ROD) documents on or before December 31, 2011. This FS supports the final remedy selection for the 200-ZP-1 OU, as described in the Remedial Investigation/Feasibility Study Work Plan for the 200-ZP-1 Groundwater Operable Unit (referred to as the 200-ZP-1 RI/FS work plan) (DOE/RL-2003-55), as agreed upon by RL and EPA. Tri-Party Agreement Milestone M-015-48B required Draft A of the 200-ZP-1 OU FS and proposed plan to be transmitted to EPA by September 30, 2007. As agreed to with EPA in the 200 Area Unit Managers Meeting Groundwater Operable Unit Status (FH-0503130), the baseline risk assessment (BRA) was delayed from inclusion in the remedial investigation (RI) report and is completed and documented in this FS. The Remedial Investigation Report for 200-ZP-1 Groundwater Operable Unit (referred to as the 200-ZP-1 RI report) (DOE/RL-2006-24) included an evaluation of human health and ecological risks and hazards. The RI report identified the radiological and chemical contaminants of potential concern (COPCs) that represent the primary risks to human health and the environment. The complete risk assessment in this FS incorporates additional analytical data from the unconfined aquifer that were obtained during or after preparation of the RI report, particularly for carbon tetrachloride and technetium-99. This FS also includes the initial results from an ongoing study of technetium-99 contamination near WMA-T, the sampling of new wells near the 216-W-LC laundry waste crib and T Plant, updated Hanford vadose zone fate and transport modeling
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Manyam, Bala V; Dhanasekaran, Muralikrishnan; Hare, Theodore A
2004-02-01
HP-200, which contains Mucuna pruriens endocarp, has been shown to be effective in the treatment of Parkinson's disease. Mucuna pruriens endocarp has also been shown to be more effective compared to synthetic levodopa in an animal model of Parkinson's disease. The present study was designed to elucidate the long-term effect of Mucuna pruriens endocarp in HP-200 on monoaminergic neurotransmitters and its metabolite in various regions of the rat brain. HP-200 at a dose of 2.5, 5.0 or 10.0 g/kg/day was mixed with rat chow and fed daily ad lib to Sprague-Dawley rats (n = 6 for each group) for 52 weeks. Controls (n = 6) received no drug. Random assignment was made for doses and control. The rats were sacrificed at the end of 52 weeks and the neurotransmitters were analyzed in the cortex, hippocampus, substantia nigra and striatum. Oral administration of Mucuna pruriens endocarp in the form of HP-200 had a significant effect on dopamine content in the cortex with no significant effect on levodopa, norepinephrine or dopamine, serotonin, and their metabolites- HVA, DOPAC and 5-HIAA in the nigrostriatal tract. The failure of Mucuna pruriens endocarp to significantly affect dopamine metabolism in the striatonigral tract along with its ability to improve Parkinsonian symptoms in the 6-hydorxydopamine animal model and humans may suggest that its antiparkinson effect may be due to components other than levodopa or that it has an levodopa enhancing effect. Copyright 2004 John Wiley & Sons, Ltd. Copyright 2004 John Wiley & Sons, Ltd.
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17 CFR 200.64 - Judicial review.
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Judicial review. 200.64... AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.64 Judicial review. The Congress has provided for review by the courts of the decisions and orders by this Commission. Members should recognize...