WorldWideScience

Sample records for air cargo inspection

  1. Air Cargo Security

    Science.gov (United States)

    2007-07-30

    passenger and all-cargo aircraft. The air cargo system consists of a large, complex distribution network linking manufacturers and shippers to freight...free transportation to San Jose, California. His only luggage was a guitar case that concealed hammers, mallets, a knife, and a spear gun. At the...authorities and airplane manufacturers study methods to mitigate the effects of in-flight explosions.76 The FAA has had a active research program in blast

  2. 49 CFR 176.39 - Inspection of cargo.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Inspection of cargo. 176.39 Section 176.39... Requirements § 176.39 Inspection of cargo. (a) Manned vessels. The carrier, its agents, and any person... thereafter, weather permitting, in order to ensure that the cargo is in a safe condition and that no...

  3. Installation of the Canadian Muon Cargo Inspection System at CRL

    Science.gov (United States)

    2014-04-01

    Installation of the Canadian Muon Cargo Inspection System at CRL Prepared by: Guy Jonkmans Atomic Energy of Canada Limited Chalk River ON...INSTALLATION OF THE CANADIAN MUON CARGO INSPECTION SYSTEM AT CRL 153-30100-REPT-001 Revision 0 2013/02/19 UNRESTRICTED 2013/02/19 ILLIMITÉ 153...30100-REPT-001 2013/02/19 Report, General Installation of the Canadian Muon Cargo Inspection System at CRL Research and Development 153-30100

  4. 76 FR 51847 - Air Cargo Screening

    Science.gov (United States)

    2011-08-18

    ... Exporters and Importers, Cargo Airline Association, Council of Supply Chain Management Professionals... the air cargo supply chain. TSA Response: The 9/11 Act required the Secretary of Homeland Security to... conduct screening at stages earlier within the cargo supply chain and off-airport. Thus, the CCSP...

  5. OPTIMAL GOODS STOWAGE IN AIR CARGO TERMINALS

    Directory of Open Access Journals (Sweden)

    Gennadiy Yun

    2011-03-01

    Full Text Available Abstract. Lack of system research done by domestic and foreign scientists in the field of optimal cargostraffic distribution problem in Air Cargo Terminal, proves necessity of investigation and optimization of thisprocess. Mathematical models and algorithms of optimal problem solving for air cargos distribution inwarehouses on the basis of established functional dependence between freight flow stowage in warehousesand transport vehicle loading (unloading processes are presented in the article.Keywords:algorithms, dimensions of air cargo terminal, effectiveness of loading-unloading processes,freight flow, models.

  6. OPTIMAL GOODS STOWAGE IN AIR CARGO TERMINALS

    OpenAIRE

    Yun, Gennadiy; Gyrych, Victoria

    2011-01-01

    Abstract. Lack of system research done by domestic and foreign scientists in the field of optimal cargostraffic distribution problem in Air Cargo Terminal, proves necessity of investigation and optimization of thisprocess. Mathematical models and algorithms of optimal problem solving for air cargos distribution inwarehouses on the basis of established functional dependence between freight flow stowage in warehousesand transport vehicle loading (unloading) processes are presented in the articl...

  7. Optimization of the air cargo supply chain

    Directory of Open Access Journals (Sweden)

    María Pérez Bernal

    2012-10-01

    Full Text Available Purpose: This paper aims to evaluate and optimize the various operations within the air cargo chain. It pursues to improve the efficiency of the air cargo supply chain and to provide more information to the decision-makers to optimize their fields.Design/methodology/approach: The method used is a process simulation modelling software, WITNESS, which provides information to the decision-makers about the most relevant parameters subject to optimization. The input for the simulation is obtained from a qualitative analysis of the air cargo supply chain with the involved agents and from a study of the external trade by air mode, given that their behaviour depend on the location. The case study is focused on a particular location, the Case of Zaragoza Airport (Spain.Findings: This paper demonstrates that efficiency of the air cargo supply chain can increase by leveraging several parameters such as bottlenecks, resources or warehouses.Originality/value: It explores the use of a simulation modeling software originally intended for manufacturing processes and extended to support decision making processes in the area of air cargo.

  8. Monte-Carlo Simulations of Radiation-Induced Activation in a Fast-Neutron and Gamma- Based Cargo Inspection System

    CERN Document Server

    Bromberger, B; Brandis, M; Dangendorf, V; Goldberg, M B; Kaufmann, F; Mor, I; Nolte, R; Schmiedel, M; Tittelmeier, K; Vartsky, D; Wershofen, H

    2012-01-01

    An air cargo inspection system combining two nuclear reaction based techniques, namely Fast-Neutron Resonance Radiography and Dual-Discrete-Energy Gamma Radiography is currently being developed. This system is expected to allow detection of standard and improvised explosives as well as special nuclear materials. An important aspect for the applicability of nuclear techniques in an airport inspection facility is the inventory and lifetimes of radioactive isotopes produced by the neutron and gamma radiation inside the cargo, as well as the dose delivered by these isotopes to people in contact with the cargo during and following the interrogation procedure. Using MCNPX and CINDER90 we have calculated the activation levels for several typical inspection scenarios. One example is the activation of various metal samples embedded in a cotton-filled container. To validate the simulation results, a benchmark experiment was performed, in which metal samples were activated by fast-neutrons in a water-filled glass jar. T...

  9. National Security Science and Technology Initiative: Air Cargo Screening

    Energy Technology Data Exchange (ETDEWEB)

    Bingham, Philip R [ORNL; White, Tim [Pacific Northwest National Laboratory (PNNL); Cespedes, Ernesto [Idaho National Laboratory (INL); Bowerman, Biays [Brookhaven National Laboratory (BNL); Bush, John [Battelle

    2010-11-01

    The non-intrusive inspection (NII) of consolidated air cargo carried on commercial passenger aircraft continues to be a technically challenging, high-priority requirement of the Department of Homeland Security's Science and Technology Directorate (DHS S&T), the Transportation Security Agency and the Federal Aviation Administration. The goal of deploying a screening system that can reliably and cost-effectively detect explosive threats in consolidated cargo without adversely affecting the flow of commerce will require significant technical advances that will take years to develop. To address this critical National Security need, the Battelle Memorial Institute (Battelle), under a Cooperative Research and Development Agreement (CRADA) with four of its associated US Department of Energy (DOE) National Laboratories (Oak Ridge, Pacific Northwest, Idaho, and Brookhaven), conducted a research and development initiative focused on identifying, evaluating, and integrating technologies for screening consolidated air cargo for the presence of explosive threats. Battelle invested $8.5M of internal research and development funds during fiscal years 2007 through 2009. The primary results of this effort are described in this document and can be summarized as follows: (1) Completed a gap analysis that identified threat signatures and observables, candidate technologies for detection, their current state of development, and provided recommendations for improvements to meet air cargo screening requirements. (2) Defined a Commodity/Threat/Detection matrix that focuses modeling and experimental efforts, identifies technology gaps and game-changing opportunities, and provides a means of summarizing current and emerging capabilities. (3) Defined key properties (e.g., elemental composition, average density, effective atomic weight) for basic commodity and explosive benchmarks, developed virtual models of the physical distributions (pallets) of three commodity types and three

  10. Development of sup 6 sup 0 Co cargo train inspection system

    CERN Document Server

    Wu Zhi Fang

    2002-01-01

    The author introduces the research and development of sup 6 sup 0 Co cargo train inspection system. With the use of radiography principle, every car image is acquired when the cargo train runs through the inspection channel. It is evaluated whether the cargo in car matches the corresponding customs declaration information with digital image processing techniques. The system has been installed in railway port at Manzhouli Customs

  11. Tackling the x-ray cargo inspection challenge using machine learning

    Science.gov (United States)

    Jaccard, Nicolas; Rogers, Thomas W.; Morton, Edward J.; Griffin, Lewis D.

    2016-05-01

    The current infrastructure for non-intrusive inspection of cargo containers cannot accommodate exploding com-merce volumes and increasingly stringent regulations. There is a pressing need to develop methods to automate parts of the inspection workflow, enabling expert operators to focus on a manageable number of high-risk images. To tackle this challenge, we developed a modular framework for automated X-ray cargo image inspection. Employing state-of-the-art machine learning approaches, including deep learning, we demonstrate high performance for empty container verification and specific threat detection. This work constitutes a significant step towards the partial automation of X-ray cargo image inspection.

  12. Aviation System Analysis Capability Air Carrier Investment Model-Cargo

    Science.gov (United States)

    Johnson, Jesse; Santmire, Tara

    1999-01-01

    The purpose of the Aviation System Analysis Capability (ASAC) Air Cargo Investment Model-Cargo (ACIMC), is to examine the economic effects of technology investment on the air cargo market, particularly the market for new cargo aircraft. To do so, we have built an econometrically based model designed to operate like the ACIM. Two main drivers account for virtually all of the demand: the growth rate of the Gross Domestic Product (GDP) and changes in the fare yield (which is a proxy of the price charged or fare). These differences arise from a combination of the nature of air cargo demand and the peculiarities of the air cargo market. The net effect of these two factors are that sales of new cargo aircraft are much less sensitive to either increases in GDP or changes in the costs of labor, capital, fuel, materials, and energy associated with the production of new cargo aircraft than the sales of new passenger aircraft. This in conjunction with the relatively small size of the cargo aircraft market means technology improvements to the cargo aircraft will do relatively very little to spur increased sales of new cargo aircraft.

  13. Comparative International Air Cargo Solutions: The Pathway to a Resilient, Adaptable, Balanced and Sustainable Secure Global Air Cargo Supply Chain

    Science.gov (United States)

    2013-12-01

    systems. Dr. Gerald L. Dillinham, the Director of Physical Infrastructure Issues, GAO noted during his testimony that securing the nation’s aviation...9697. Karp , Aaron. “Air Cargo Flattens Out.” Air Transport World 46, no. 1 (2009): 37–39. 74 Kersey, J. W. “The Economics of Air Cargo (Analysis of...Transportation, U.S. Senate. Aviation Security: Progress since September 11, 2001, and the Challenges Ahead. Statement of Gerald L. Dillingham

  14. Aggregating Secondary Source Data for Air Cargo Prescreening Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to improve the effectiveness of air cargo prescreening by enabling background knowledge about companies and products to be used for threat assessment. The...

  15. Design and Inspection of Liquid Cargo Piping of Chemical Tanker

    Institute of Scientific and Technical Information of China (English)

    Ying Sheng; Jiang Chengsong

    2012-01-01

    There is a great variety of liquid chemicals, and many shipowners are not clear about the cargos their ships will carry at the early stage of the design and construction of chemical tankers. In addition, because of the inclination to choose low cost construction material due to cost concern, the sources of cargos that ships can carry are greatly limited and the operation efficiency will be influenced. What should we do to avoid such situations?

  16. 19 CFR 122.117 - Requirements for transit air cargo transport.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Requirements for transit air cargo transport. 122... Requirements for transit air cargo transport. (a) Transportation—(1) Port to port. Transit air cargo may be... cargo, a receipt shall be given. The receipt shall be made by the airline responsible for transport...

  17. 19 CFR 122.48 - Air cargo manifest.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Air cargo manifest. 122.48 Section 122.48 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY AIR COMMERCE REGULATIONS Aircraft Entry and Entry Documents; Electronic Manifest Requirements...

  18. Optimisation of key performance measures in air cargo demand management

    Directory of Open Access Journals (Sweden)

    Alexander May

    2014-03-01

    Full Text Available This article sought to facilitate the optimisation of key performance measures utilised for demand management in air cargo operations. The focus was on the Revenue Management team at Virgin Atlantic Cargo and a fuzzy group decision-making method was used. Utilising intelligent fuzzy multi-criteria methods, the authors generated a ranking order of ten key outcome-based performance indicators for Virgin Atlantic air cargo Revenue Management. The result of this industry-driven study showed that for Air Cargo Revenue Management, ‘Network Optimisation’ represents a critical outcome-based performance indicator. This collaborative study contributes to existing logistics management literature, especially in the area of Revenue Management, and it seeks to enhance Revenue Management practice. It also provides a platform for Air Cargo operators seeking to improve reliability values for their key performance indicators as a means of enhancing operational monitoring power.

  19. 77 FR 65006 - Air Cargo Advance Screening (ACAS) Pilot Program

    Science.gov (United States)

    2012-10-24

    ..., such as the ACAS pilot, in 19 CFR 101.9. Advance Electronic Air Cargo Information Required by 19 CFR... need to sign an Interconnection Security Agreement (ISA) or amend their existing ISA, if necessary, and... connection covered by a valid and up to date ISA will have already met these requirements. ACAS...

  20. Shift designs for freight handling personnel at air cargo terminals

    DEFF Research Database (Denmark)

    Rong, Aiying; Grunow, Martin

    2009-01-01

    This paper presents an integrated mixed integer linear programming (MILP) model for determining manpower requirements and related personnel shift designs for the build-up and break-down of the unit load devices (ULDs) at the air cargo terminal to minimize manpower costs. To utilize the manpower...

  1. 77 FR 65395 - Air Cargo Advance Screening (ACAS) Pilot Program

    Science.gov (United States)

    2012-10-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Air Cargo Advance Screening (ACAS) Pilot Program Correction In notice document 2012-26031 appearing on pages 65006-65009 in the issue of October 24, 2012 make...

  2. Cargo and Container X-Ray Inspection with Intra-Pulse Multi-Energy Method for Material Discrimination

    Science.gov (United States)

    Saverskiy, Aleksandr Y.; Dinca, Dan-Cristian; Rommel, J. Martin

    The Intra-Pulse Multi-Energy (IPME) method of material discrimination mitigates main disadvantages of the traditional "interlaced" approach: ambiguity caused by sampling different regions of cargo and reduction of effective scanning speed. A novel concept of creating multi-energy probing pulses using a standing-wave structure allows maintaining a constant energy spectrum while changing the time duration of each sub-pulse and thus enables adaptive cargo inspection. Depending on the cargo density, the dose delivered to the inspected object is optimized for best material discrimination, maximum material penetration, or lowest dose to cargo. A model based on Monte-Carlo simulation and experimental reference points were developed for the optimization of inspection conditions.

  3. 75 FR 63192 - Intent To Request Renewal From OMB of One Current Public Collection of Information: Air Cargo...

    Science.gov (United States)

    2010-10-14

    ... Collection of Information: Air Cargo Security Requirements AGENCY: Transportation Security Administration... under a security program, and all-cargo carriers: Security programs, security threat assessments (STA), known shipper data via the Known Shipper Management System (KSMS), cargo screening reporting,...

  4. Domestic & International Air Cargo Activity: National and Selected Hub Forecasts.

    Science.gov (United States)

    1979-11-01

    world regional models. These six world regions are: North America excluding U.S., South America, Europe, Asia, Australia and Oceania, and Africa . For each...1 I et p(B) p(B) = (I- PIB - P2B 2,---, PpB ) and B is a backward shift operator. The part f (Xt’s 1 ) is a predictable component, which contains the...world regions are: North America excluding U.S., South America, Europe, Asia, Australia and Oceania and Africa . Statistics of air cargo flow for these

  5. Optimization of the imported air express cargo distribution problem

    Directory of Open Access Journals (Sweden)

    Hwang, T.L.

    2013-03-01

    Full Text Available This study examines the delivering network of imported air express cargo as an integrated multi-depot vehicle routing problem. Integrated multi-depot vehicle routing problem attempts to decide which service centers should be used and how much freight should be unloaded in each service center. The role of an exchange point which is allowing the delivery vans and shuttles to exchange imported and exported goods is also addressed. Test results demonstrate the feasibility of the four models so these are highly promising for use in a diverse array of applications, such as in home delivery and reverse logistics.

  6. 19 CFR 122.49 - Correction of air cargo manifest or air waybill.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Correction of air cargo manifest or air waybill. 122.49 Section 122.49 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND...; Electronic Manifest Requirements for Passengers, Crew Members, and Non-Crew Members Onboard...

  7. 46 CFR 154.1710 - Exclusion of air from cargo tank vapor spaces.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Exclusion of air from cargo tank vapor spaces. 154.1710... Operating Requirements § 154.1710 Exclusion of air from cargo tank vapor spaces. When a vessel is carrying acetaldehyde, butadiene, ethylene oxide, or vinyl chloride, the master shall ensure that air is: (a)...

  8. Waste Crate and Container Imaging Using the Vehicle and Cargo Inspection System. Innovative Technology Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-07-01

    The Vehicle and Cargo Inspection System (VACIS) is a highly penetrating gamma ray imaging system that provides a means to non-invasively image crate contents prior to crate disassembly. The VACIS unit uses a 1.6 Curie collimated source (Cesium-137) aimed at a linear detector to create an image as the unit passes by the crate. In the demonstrated mobile unit, the source and detector were mounted on a boom truck. As the crate passed between the source and detector, a near real-time composite image of the contents was constructed from the linear image of the VACIS unit's on board computer and recorded on disk.

  9. Design and application of radiation apparatus for sup 6 sup 0 Co cargo train on-line inspection system

    CERN Document Server

    Wu Zhi Fang; Zhang Yuai

    2002-01-01

    Based on the special requirement for radiation apparatus of sup 6 sup 0 Co cargo train on-line inspection system, a radiation apparatus including two-level shutter, working container, storing container and electromagnetism are designed. The makeup, working mode and functional realization of the radiation apparatus are introduced. The system is used in Manzhouli customs cargo train on-line inspection system. The practice shows that the radiation apparatus is reliable to work steadily and the operating speed of the main shutter can reach 0.1 s open and 0.15 s close

  10. Monte Carlo parametric studies of neutron interrogation with the Associated Particle Technique for cargo container inspections

    Science.gov (United States)

    Deyglun, Clément; Carasco, Cédric; Pérot, Bertrand

    2014-06-01

    The detection of Special Nuclear Materials (SNM) by neutron interrogation is extensively studied by Monte Carlo simulation at the Nuclear Measurement Laboratory of CEA Cadarache (French Alternative Energies and Atomic Energy Commission). The active inspection system is based on the Associated Particle Technique (APT). Fissions induced by tagged neutrons (i.e. correlated to an alpha particle in the DT neutron generator) in SNM produce high multiplicity coincidences which are detected with fast plastic scintillators. At least three particles are detected in a short time window following the alpha detection, whereas nonnuclear materials mainly produce single events, or pairs due to (n,2n) and (n,n'γ) reactions. To study the performances of an industrial cargo container inspection system, Monte Carlo simulations are performed with the MCNP-PoliMi transport code, which records for each neutron history the relevant information: reaction types, position and time of interactions, energy deposits, secondary particles, etc. The output files are post-processed with a specific tool developed with ROOT data analysis software. Particles not correlated with an alpha particle (random background), counting statistics, and time-energy resolutions of the data acquisition system are taken into account in the numerical model. Various matrix compositions, suspicious items, SNM shielding and positions inside the container, are simulated to assess the performances and limitations of an industrial system.

  11. National Security Science and Technology Initiative: Air Cargo Screening, Final Report for CRADA Number NFE-07-01081

    Energy Technology Data Exchange (ETDEWEB)

    Bingham, Philip [ORNL; Bush, John [Battelle Memorial Institute; Bowerman, Biays [Brookhaven National Laboratory; Cespedes, Ernesto [Idaho National Laboratory; White, Timothy [Pacific Northwest National Laboratory

    2004-12-01

    The non-intrusive inspection (NII) of consolidated air cargo carried on commercial passenger aircraft continues to be a technically challenging, high-priority requirement of the Department of Homeland Security’s Science and Technology Directorate (DHS S&T), the Transportation Security Agency and the Federal Aviation Administration. The goal of deploying a screening system that can reliably and cost-effectively detect explosive threats in consolidated cargo without adversely affecting the flow of commerce will require significant technical advances that will take years to develop. To address this critical National Security need, the Battelle Memorial Institute (Battelle), under a Cooperative Research and Development Agreement (CRADA) with four of its associated US Department of Energy (DOE) National Laboratories (Oak Ridge, Pacific Northwest, Idaho, and Brookhaven), conducted a research and development initiative focused on identifying, evaluating, and integrating technologies for screening consolidated air cargo for the presence of explosive threats. Battelle invested $8.5M of internal research and development funds during fiscal years 2007 through 2009.

  12. Analysis of a Gross Counting Decision Metric for use in Threat Detection During Cargo Container Inspection

    Energy Technology Data Exchange (ETDEWEB)

    Hall, J

    2006-04-28

    LLNL is actively engaged in the development of a variety of advanced technologies for use in detecting potential threats in sea-going cargo containers, particularly the presence of hidden special nuclear materials (SNM). One such project is the so-called ''Nuclear Car Wash'' (NCW), which uses a high-energy neutron probe to scan the container. High-energy, {beta}-delayed {gamma}-rays emitted during the decay of short-lived, neutron-induced fission products are then taken as a signature of fissionable material. There are a number of different threat decision metrics that one could imagine using in conjunction with an inspection system such as the NCW; however, the most straightforward approach might be to simply compare the total number of counts that our detector records during some suitably chosen time interval to the average background signal that one would expect from a ''clean'' container during the same interval. The purpose of this report is to describe the basic statistical properties of a decision metric of this sort and outline the procedures for using it in experimental practice.

  13. Air cargo: An Integrated Systems View. 1978 Summer Faculty Fellowship Program in Engineering Systems Design

    Science.gov (United States)

    Keaton, A. (Editor); Eastman, R. (Editor); Hargrove, A. (Editor); Rabiega, W. (Editor); Olsen, R. (Editor); Soberick, M. (Editor)

    1978-01-01

    The national air cargo system is analyzed and how it should be in 1990 is prescribed in order to operate successfully through 2015; that is through one equipment cycle. Elements of the system which are largely under control of the airlines and the aircraft manufacturers are discussed. The discussion deals with aircraft, networks, facilities, and procedures. The regulations which govern the movement of air freight are considered. The larger public policy interests which must be served by the kind of system proposed, the air cargo integrated system (ACIS), are addressed. The possible social, economical, political, and environment impacts of the system are considered. Recommendations are also given.

  14. 19 CFR 122.48a - Electronic information for air cargo required in advance of arrival.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Electronic information for air cargo required in... OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY AIR COMMERCE REGULATIONS Aircraft Entry and Entry Documents; Electronic Manifest Requirements for Passengers, Crew Members, and Non-Crew Members...

  15. The Arteries of Global Trade: Industrial Restructuring and Technological Change in the Transatlantic Air Cargo Industry

    Science.gov (United States)

    Schwarz, Guido

    2010-01-01

    Air cargo enjoys a special importance: together with maritime transport it is the backbone of global trade and is indispensable for contemporary globalization. Air transport is the only mode that combines worldwide reach with high speed. Nonetheless there is a dearth of geographic research that analyzes the current restructuring affecting the air…

  16. Air cargo market outlook and impact via the NASA CLASS project. [Cargo/Logistics Airlift Systems Study

    Science.gov (United States)

    Winston, M. M.; Conner, D. W.

    1980-01-01

    An overview is given of the Cargo/Logistics Airlift Systems Study (CLASS) project which was a 10 man-year effort carried out by two contractor teams, aimed at defining factors impacting future system growth and obtaining market requirements and design guidelines for future air freighters. Growth projection was estimated by two approaches: one, an optimal systems approach with a more efficient and cost effective system considered as being available in 1990; and the other, an evolutionary approach with an econometric behavior model used to predict long term evolution from the present system. Both approaches predict significant growth in demand for international air freighter services and less growth for U.S. domestic services. Economic analysis of air freighter fleet options indicate very strong market appeal of derivative widebody transports in 1990 with little incentive to develop all new dedicated air freighters utilizing the 1990's technology until sometime beyond the year 2000. Advanced air freighters would be economically attractive for a wide range of payload sizes (to 500 metric tons), however, if a government would share in the RD and T costs by virtue of its needs for a slightly modified version of a civil air freighter design (a.g. military airlifter).

  17. The Influence of Freight Trains on the Air Cargo in Kuwait International Airport

    Directory of Open Access Journals (Sweden)

    Fadala Hassan Alfadala

    2017-03-01

    Full Text Available Surrounded by countries who are moving continually towards economic development and stability, Kuwait has moved to establishing freight trains on the Air Cargo in Kuwait International Airport to meet the ever changing and increasing number of both passenger and cargoes going in and out of the country. As a member of the Gulf Cooperation Council or GCC it is clearly seen that as most of its member countries drive towards a collective effort to connect together by means of railroad networks, Kuwait’s effort to move transportation of cargoes to and from the Kuwait International Airport by linking with the GCC’s project to create railroad networks, the proposed ―Cargo City‖ becomes a major part of the realization of the development of the KIA which shall help with the aim to widen trade within and across GCC countries.

  18. 49 CFR 180.407 - Requirements for test and inspection of specification cargo tanks.

    Science.gov (United States)

    2010-10-01

    ... appurtenances and structural attachments on the cargo tank including, but not limited to, suspension system...; (vii) Areas near upper coupler (fifth wheel) assembly attachments; (viii) Areas near suspension system... PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS...

  19. 77 FR 11145 - Intent to Request Renewal From OMB of One Current Public Collection of Information: Air Cargo...

    Science.gov (United States)

    2012-02-24

    ... Collection of Information: Air Cargo Security Requirements AGENCY: Transportation Security Administration...-cargo carriers. The collections of information that make up this ICR are security programs, security threat assessments (STA), known shipper data via the Known Shipper Management System (KSMS), Air...

  20. 19 CFR 103.31a - Advance electronic information for air, truck, and rail cargo; Importer Security Filing...

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Advance electronic information for air, truck, and rail cargo; Importer Security Filing information for vessel cargo. 103.31a Section 103.31a Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE...

  1. An Optimization Model of the Single-Leg Air Cargo Space Control Based on Markov Decision Process

    Directory of Open Access Journals (Sweden)

    Chun-rong Qin

    2012-01-01

    Full Text Available Based on the single-leg air cargo issues, we establish a dynamic programming model to consider the overbooking and space inventory control problem. We analyze the structure of optimal booking policy for every kind of booking requests and show that the optimal booking decision is of threshold type (known as booking limit policy. Our research provides a theoretical support for the air cargo space control.

  2. 77 FR 38857 - Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units of Normal...

    Science.gov (United States)

    2012-06-29

    ... COMMISSION Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units of Normal..., Inspection, and Testing Criteria for Air Filtration and Adsorption Units of Normal Atmosphere Cleanup Systems..., entitled, ``Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units of...

  3. 76 FR 82323 - Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units

    Science.gov (United States)

    2011-12-30

    ... COMMISSION Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units AGENCY: Nuclear...-1274, ``Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units of....'' This guide applies to the design, inspection, and testing of air filtration and iodine adsorption...

  4. H-CANYON AIR EXHAUST TUNNEL INSPECTION VEHICLE DEVELOPMENT

    Energy Technology Data Exchange (ETDEWEB)

    Minichan, R.; Fogle, R.; Marzolf, A.

    2011-05-24

    The H-Canyon at Savannah River Site is a large concrete structure designed for chemical separation processes of radioactive material. The facility requires a large ventilation system to maintain negative pressure in process areas for radioactive contamination control and personnel protection. The ventilation exhaust is directed through a concrete tunnel under the facility which is approximately five feet wide and 8 feet tall that leads to a sand filter and stack. Acidic vapors in the exhaust have had a degrading effect on the surface of the concrete tunnels. Some areas have been inspected; however, the condition of other areas is unknown. Experience from historical inspections with remote controlled vehicles will be discussed along with the current challenge of inspecting levels below available access points. The area of interest in the exhaust tunnel must be accessed through a 14 X 14 inch concrete plug in the floor of the hot gang valve corridor. The purpose for the inspection is to determine the condition of the inside of the air tunnel and establish if there are any structural concerns. Various landmarks, pipe hangers and exposed rebar are used as reference points for the structural engineers when evaluating the current integrity of the air tunnel.

  5. Primary Beam Air Kerma Dependence on Distance from Cargo and People Scanners

    Energy Technology Data Exchange (ETDEWEB)

    Strom, Daniel J.; Cerra, Frank

    2016-06-01

    The distance dependence of air kerma or dose rate of the primary radiation beam is not obvious for security scanners of cargo and people in which there is relative motion between a collimated source and the person or object being imaged. To study this problem, one fixed line source and three moving-source scan-geometry cases are considered, each characterized by radiation emanating perpendicular to an axis. The cases are 1) a stationary line source of radioactive material, e.g., contaminated solution in a pipe; 2) a moving, uncollimated point source of radiation that is shuttered or off when it is stationary; 3) a moving, collimated point source of radiation that is shuttered or off when it is stationary; and 4) a translating, narrow “pencil” beam emanating in a flying-spot, raster pattern. Each case is considered for short and long distances compared to the line source length or path traversed by a moving source. The short distance model pertains mostly to dose to objects being scanned and personnel associated with the screening operation. The long distance model pertains mostly to potential dose to bystanders. For radionuclide sources, the number of nuclear transitions that occur a) per unit length of a line source, or b) during the traversal of a point source, is a unifying concept. The “universal source strength” of air kerma rate at a meter from the source can be used to describe x-ray machine or radionuclide sources. For many cargo and people scanners with highly collimated fan or pencil beams, dose varies as the inverse of the distance from the source in the near field and with the inverse square of the distance beyond a critical radius. Ignoring the inverse square dependence and using inverse distance dependence is conservative in the sense of tending to overestimate dose.

  6. Sensor-based navigation of air duct inspection mobile robots

    Science.gov (United States)

    Koh, Kyoungchul; Choi, H. J.; Kim, Jae-Seon; Ko, Kuk Won; Cho, Hyungsuck

    2001-02-01

    12 This paper deals with an image sensor system and its position estimation algorithm for autonomous duct cleaning and inspection mobile robots. For the real application, a hierarchical control structure that consists of robot motion controller and image sensor system is designed considering the efficient and autonomous motion behaviors in narrow space such as air ducts. The sensor's system consists of a CCD camera and two laser sources to generate slit beams. The image of the structured lights is used for calculating the geometric parameters of the air ducts which are usually designed with a rectangular section. With the acquired 3D information about the environment, the mobile robot with two differential driving wheels is able to autonomously navigates along the duct path without any human intervention. For real time navigation, the relative position estimation of the robot are performed from 3D image reconstructed by the sensor system. The calibration and image processing methods used for the sensor system are presented with the experimental data. The experimental results show the possibility of the sensor based navigation which is important for effective duct cleaning by small mobile robots.

  7. Design and model selection for unit cargo handling system at air cargo terminal%航空货运站集装货处理系统设计选型研究

    Institute of Scientific and Technical Information of China (English)

    梅宝兴

    2012-01-01

    航空货运站是专门处理航空货物的地面设施.根据近年来国内航空货运发展的新趋势,分析了集装货处理系统设计选型阶段需重点考虑的问题,并对存储容量、堆垛机数量等关键参数的确定进行了较为深入的研究,为航空货运集装货处理系统的设计优化提供了思路.%The air cargo terminal is the ground-level facility to specifically handle air cargoes. Based on the new trend of domestic air cargo market in recent years, certain key necessary problems jegarding design and model selection of unit cargo handling system are analyzed, with further research on determination of key parameters such as storage capacity and quantity of stackers, etc. , which provides ideas for design optimization of unit cargo handling system.

  8. Monte Carlo analysis of megavoltage x-ray interaction-induced signal and noise in cadmium tungstate detectors for cargo container inspection

    Science.gov (United States)

    Kim, J.; Park, J.; Kim, J.; Kim, D. W.; Yun, S.; Lim, C. H.; Kim, H. K.

    2016-11-01

    For the purpose of designing an x-ray detector system for cargo container inspection, we have investigated the energy-absorption signal and noise in CdWO4 detectors for megavoltage x-ray photons. We describe the signal and noise measures, such as quantum efficiency, average energy absorption, Swank noise factor, and detective quantum efficiency (DQE), in terms of energy moments of absorbed energy distributions (AEDs) in a detector. The AED is determined by using a Monte Carlo simulation. The results show that the signal-related measures increase with detector thickness. However, the improvement of Swank noise factor with increasing thickness is weak, and this energy-absorption noise characteristic dominates the DQE performance. The energy-absorption noise mainly limits the signal-to-noise performance of CdWO4 detectors operated at megavoltage x-ray beam.

  9. Role of Air Cargo and Road Feeder Services for Regional Airports – Case Studies from the Baltic Sea Region

    Directory of Open Access Journals (Sweden)

    Beifert Anatoli

    2016-06-01

    Full Text Available Although airports play an important role the global and European economies, according to the new guidelines of the EU Commission on the new state aid rules for a competitive aviation industry (EC, 2014, it will be more difficult for unprofitable airports, to get financial public subsidies in the future. The Commission noted that the majority of regional airports experience severe problems to cover their operative costs, resulting from among other things from overlapping of airports’ catchment areas. The main objective of the above mentioned measures is not to close the regional airports, but to motivate them to operate on cost efficient, profitable and more flexible basis, stating however that and that the most inefficient airports will be still closed. In order face upcoming challenges, the regional airports shall reconsider their future development plans. Traditionally, the airports including small and regional airports focus on the passenger traffic and thus, the possible benefits and opportunities of the air cargo market are totally underestimated or even completely ignored. Most regional airports in the Baltic Sea region act totally isolated and do not have a clear picture of the current situation on the international air cargo market today, its future perspectives and sustainable development plans remain basically hidden. There are some examples when trying to meet the market demand, the regional airports have made huge, but unfortunately unjustified investments, e.g. improving airport infrastructure, runways, etc. However, the airports’ infrastructural investments alone cannot fulfil the expected “remedy” role for the airports’ sustainability. This paper aims at investigating the positioning and the role of the regional airports in the current hub-and-spoke network, focusing on the relevance and potential of the air cargo sector for the regional airports development. The optional freight value proposition for the development of

  10. Scatter in cargo radiography.

    Science.gov (United States)

    Miller, Erin A; Caggiano, Joseph A; Runkle, Robert C; White, Timothy A; Bevill, Aaron M

    2011-03-01

    As a complement to passive detection systems, radiographic inspection of cargo is an increasingly important tool for homeland security because it has the potential to detect highly attenuating objects associated with special nuclear material or surrounding shielding, in addition to screening for items such as drugs or contraband. Radiographic detection of such threat objects relies on high image contrast between regions of different density and atomic number (Z). Threat detection is affected by scatter of the interrogating beam in the cargo, the radiographic system itself, and the surrounding environment, which degrades image contrast. Here, we estimate the extent to which scatter plays a role in radiographic imaging of cargo containers. Stochastic transport simulations were performed to determine the details of the radiography equipment and surrounding environment, which are important in reproducing measured data and to investigate scatter magnitudes for typical cargo. We find that scatter plays a stronger role in cargo radiography than in typical medical imaging scenarios, even for low-density cargo, with scatter-to-primary ratios ranging from 0.14 for very low density cargo, to between 0.20 and 0.40 for typical cargo, and higher yet for dense cargo.

  11. 我国航空货运信息化发展现状与对策%The Status and Countermeasures of Development of Chinese Air Cargo Informatization

    Institute of Scientific and Technical Information of China (English)

    曾小林

    2015-01-01

    With the rapid development of the air cargo market. The role of the information technology becomes more and more important. This article points out the development status of our air cargo informatization by introducing the development of the world air cargo informatization. It comprehensively analyzes the main problems of the air cargo informatization in our country and puts forward countermeasures and suggestions to speed up the air cargo informatization construction in China on the basis of learning from foreign advanced experience and summing up the experience itself.%随着航空货运市场的快速发展,信息技术的作用越来越重要。本文通过介绍我国航空货运信息化的发展历程和现状,全面剖析了我国航空货运信息化存在的主要问题,在学习借鉴国外先进经验和总结自身经验教训的基础上,系统提出加快我国航空货运信息化建设的对策措施建议。

  12. 77 FR 60481 - Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units of Post-Accident...

    Science.gov (United States)

    2012-10-03

    ... COMMISSION Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units of Post-Accident..., and Testing Criteria for Air Filtration and Adsorption Units of Post-accident Engineered-Safety... design, inspection, and testing of air filtration and iodine adsorption units of...

  13. Laser ultrasonic inspection system (LUIS) at the Sacramento Air Logistics Center

    Energy Technology Data Exchange (ETDEWEB)

    Fiedler, C. [Air Force Materials Lab., Wright Patterson AFB, OH (United States); Ducharme, T.; Kwan, J. [SM-ALC/TIMS, McClellan AFB, CA (United States)

    1996-12-31

    The usage of composite parts for critical applications on Air Force aircraft increases significantly with each new aircraft design. These composite parts are susceptible to delaminations, disbonds, and impact damage. As part of its mission to validate the integrity of aging composite aircraft, the Sacramento Air Logistics Center needs to be able to rapidly, economically, and accurately inspect a wide range of composite aircraft parts. Laser based ultrasound (LBU) inspection systems can rapidly inspect composite parts because they use laser beams which can be rapidly scanned because they do not need to be incident normal to the surface. One short pulse of laser light (120 ns) is used to generate an ultrasonic pulse, which always propagates normal to the surface where it is generated. A second, much longer pulse of laser light, and an interferometer are used to detect ultrasonic echoes which are reflected by internal flaws. Both of these laser beams can be rapidly scanned across the surface of the part, which enables LBU inspections to be as much as ten times faster than conventional inspections. In addition, LBU inspections do not require the complex scan plans or expensive fixturing that squirter systems require. Because of these advantages, and because of its composite workload, the Sacramento Air Logistics Center (SM-ALC/TIMSN) has procured the Laser Ultrasonic Inspection System (LUIS) for inspecting composite parts. Since this is the first known LBU inspection system to be installed in a production environment for scanning a production workload, the capabilities of this system will be described in detail.

  14. Cargo Logistics Airlift Systems Study (CLASS). Volume 3: Cross impact between the 1990 market and the air physical distribution systems, book 2

    Science.gov (United States)

    Burby, R. J.; Kuhlman, W. H.

    1978-01-01

    Book 2 of this volume is divided into the following sections: (1) commodities and system networks; (2) future mode choice decisions and commodity air eligibility; (3) comparative cargo transportation costs - air, truck, rail and water; (4) elasticities of demand; (5) operating cost; (6) operating profit, rate making, and returns; (7) importance of rate and service on future aircraft; (8) potential market demand for new aircraft; (9) scenario of events affecting system/market growth; and (10) future study and technology requirements.

  15. 19 CFR 122.73 - General declaration and air cargo manifest.

    Science.gov (United States)

    2010-04-01

    ...; DEPARTMENT OF THE TREASURY AIR COMMERCE REGULATIONS Documents Required for Clearance and Permission To Depart; Electronic Manifest Requirements for Passengers, Crew Members, and Non-Crew Members Onboard...

  16. 19 CFR 122.115 - Labeling of cargo.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Labeling of cargo. 122.115 Section 122.115 Customs... AIR COMMERCE REGULATIONS Transit Air Cargo Manifest (TACM) Procedures § 122.115 Labeling of cargo. A warning label, as required by § 18.4(e) of this chapter, shall be attached to all transit air cargo...

  17. Vehicle inspection and maintenance, and air pollution in Mexico City

    Energy Technology Data Exchange (ETDEWEB)

    Riveros, Hector G.; Cabrera, Enrique; Ovalle, Pilar [Universidad Nacional Autonoma de Mexico, Inst. de Fisica, Mexico City (Mexico)

    2002-07-01

    Information from the Mandatory Inspection and Maintenance (I/M) Program carried out in October 1996 and the first semester of 1998 provides a useful emission database for Mexico City. Carbon monoxide (CO) and hydrocarbon (HC) exhaust emission levels were measured for at least a million private and public transportation vehicle. Analysis of this database leads us to conclude that this information can be used to test anti-pollutant policies, and is useful as a performance quality index for vehicle manufacturers. Some of the results of this analysis include: the finding of a typical exhaust emission distribution curve for each vehicle manufacturer, with differences for each brand and model for the same manufacturer, the fact that not all new vehicles pass the I/M test; and public transportation vehicles in Mexico City have almost useless catalytic converters. (Author)

  18. 30 CFR 56.13015 - Inspection of compressed-air receivers and other unfired pressure vessels.

    Science.gov (United States)

    2010-07-01

    ... other unfired pressure vessels. 56.13015 Section 56.13015 Mineral Resources MINE SAFETY AND HEALTH... and other unfired pressure vessels. (a) Compressed-air receivers and other unfired pressure vessels... applicable chapters of the National Board Inspection Code, a Manual for Boiler and Pressure Vessel...

  19. 30 CFR 57.13015 - Inspection of compressed-air receivers and other unfired pressure vessels.

    Science.gov (United States)

    2010-07-01

    ... other unfired pressure vessels. 57.13015 Section 57.13015 Mineral Resources MINE SAFETY AND HEALTH... receivers and other unfired pressure vessels. (a) Compressed-air receivers and other unfired pressure... the applicable chapters of the National Board Inspection Code, a Manual for Boiler and Pressure...

  20. Field Operations and Enforcement Manual for Air Pollution Control. Volume III: Inspection Procedures for Specific Industries.

    Science.gov (United States)

    Weisburd, Melvin I.

    The Field Operations and Enforcement Manual for Air Pollution Control, Volume III, explains in detail the following: inspection procedures for specific sources, kraft pulp mills, animal rendering, steel mill furnaces, coking operations, petroleum refineries, chemical plants, non-ferrous smelting and refining, foundries, cement plants, aluminum…

  1. Supplemental site inspection for Air Force Plant 59, Johnson City, New York, Volume 1: Investigation report

    Energy Technology Data Exchange (ETDEWEB)

    Nashold, B.; Rosenblatt, D.; Hau, J. [and others

    1995-08-01

    This summary describes a Supplemental Site Inspection (SSI) conducted by Argonne National Laboratory (ANL) at Air Force Plant 59 (AFP 59) in Johnson City, New York. All required data pertaining to this project were entered by ANL into the Air Force-wide Installation Restoration Program Information System (IRPIMS) computer format and submitted to an appropriate authority. The work was sponsored by the United States Air Force as part of its Installation Restoration Program (IRP). Previous studies had revealed the presence of contaminants at the site and identified several potential contaminant sources. Argonne`s study was conducted to answer questions raised by earlier investigations.

  2. The effects of air gap reflections during air-coupled leaky Lamb wave inspection of thin plates.

    Science.gov (United States)

    Fan, Zichuan; Jiang, Wentao; Cai, Maolin; Wright, William M D

    2016-02-01

    Air-coupled ultrasonic inspection using leaky Lamb waves offers attractive possibilities for non-contact testing of plate materials and structures. A common method uses an air-coupled pitch-catch configuration, which comprises a transmitter and a receiver positioned at oblique angles to a thin plate. It is well known that the angle of incidence of the ultrasonic bulk wave in the air can be used to preferentially generate specific Lamb wave modes in the plate in a non-contact manner, depending on the plate dimensions and material properties. Multiple reflections of the ultrasonic waves in the air gap between the transmitter and the plate can produce additional delayed waves entering the plate at angles of incidence that are different to those of the original bulk wave source. Similarly, multiple reflections of the leaky Lamb waves in the air gap between the plate and an inclined receiver may then have different angles of incidence and propagation delays when arriving at the receiver and hence the signal analysis may become complex, potentially leading to confusion in the identification of the wave modes. To obtain a better understanding of the generation, propagation and detection of leaky Lamb waves and the effects of reflected waves within the air gaps, a multiphysics model using finite element methods was established. This model facilitated the visualisation of the propagation of the reflected waves between the transducers and the plate, the subsequent generation of additional Lamb wave signals within the plate itself, their leakage into the adjacent air, and the reflections of the leaky waves in the air gap between the plate and receiver. Multiple simulations were performed to evaluate the propagation and reflection of signals produced at different transducer incidence angles. Experimental measurements in air were in good agreement with simulation, which verified that the multiphysics model can provide a convenient and accurate way to interpret the signals in

  3. Logistics Image of Outsourcing Clients to The Wireless Telecommunications Industry: How is it related to The Service Value of Air Cargo Logistics Providers?

    OpenAIRE

    2014-01-01

    This study explored the relationship between aspects of the logistics image of an outsourcing client and the service value of air cargo logistics providers (ACLPs). Given the range of client groups served by the electronics industry in Taiwan, we focused on telecommunication industries to analyze the correlation between the service value of ACLPs and the logistics image of telecommunication clients. The research subjects in this study were actual outsourcing logistics decision makers in the t...

  4. Analysis of Air Cargo Transfer Service Chain at Pudong International Airport%浦东国际机场货运中转服务链分析

    Institute of Scientific and Technical Information of China (English)

    刘锐; 崔诚靓; 陈川

    2015-01-01

    Air cargo transfer involves several participants in its operation process, including ship pers, freight forwarders, airport cargo terminal, airlines, customs and other regulatory agencies. All of the related participants constitute the entire service chain of air cargo transfer, making the air transport continuous and convenient. Based on field research into the related enterprises, this study summarizes the developing situation about the air cargo transfer at Pudong International Airport as well as the related appeals proposed by the relevant partici pants, points out the problems at Pudong International Airport and presents some suggestions from the perspec tive of service chain.%现代航空货物中转运输在其运营过程中涉及到许多参与方,包括货主、货代、机场货站、航空公司以及海关等监管机构,所有这一系列参与方构成了整个货运中转服务链条,维系着航空运输的连续性和快捷性. 在立足对浦东机场各个货运相关参与方的实地调研的基础上,通过收集整理国外枢纽机场和相关企业的资料,分析总结浦东机场各个参与方的发展现状,梳理了参与方对中转联程运输的相关诉求,指出了浦东机场货运中转服务链中所存在的相关问题,最后从服务链的角度提出改善浦东机场货运中转的建议.

  5. Characterizing Complexity of Containerized Cargo X-ray Images

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Guangxing [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martz, Harry [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Glenn, Steven [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Divin, Charles [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Birrer, Nat [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-08-19

    X-ray imaging can be used to inspect cargos imported into the United States. In order to better understand the performance of X-ray inspection systems, the X-ray characteristics (density, complexity) of cargo need to be quantified. In this project, an image complexity measure called integrated power spectral density (IPSD) was studied using both DNDO engineered cargos and stream-of-commerce (SOC) cargos. A joint distribution of cargo density and complexity was obtained. A support vector machine was used to classify the SOC cargos into four categories to estimate the relative fractions.

  6. Characterizing X-ray Attenuation of Containerized Cargo

    Energy Technology Data Exchange (ETDEWEB)

    Birrer, N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Divin, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Glenn, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Martz, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wang, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-08-02

    X-ray inspection systems can be used to detect radiological and nuclear threats in imported cargo. In order to better understand performance of these systems, the attenuation characteristics of imported cargo need to be determined. This project focused on developing image processing algorithms for segmenting cargo and using x-ray attenuation to quantify equivalent steel thickness to determine cargo density. These algorithms were applied to over 450 cargo radiographs. The results are summarized in this report.

  7. Obtaining Traffic Information by Urban Air Quality Inspection

    CERN Document Server

    Ferrante, P; Nicolosi, S; Scaccianoce, G; Traverso, M; Rizzo, G

    2011-01-01

    The level of air quality in urban centres is affected by emission of several pollutants, mainly coming from the vehicles flowing in their road networks. This is a well known phenomenon that influences the quality of life of people. Despite the deep concern of researchers and technicians, we are far from a total understanding of this phenomenon. On the contrary, the availability of reliable forecasting models would constitute an important tool for administrators in order of assessing suitable actions concerning the transportation policies, public as well private. Referring to the situation of the running fleet and the measured pollutant concentrations concerning the Italian town of Palermo, a data-deduced traffic model is here derived, its truthfulness being justified by a fuzzyfication of the phenomenon. A first validation of the model is supplied by utilising the emissions characteristics and the pollutant concentrations referring to a two years period of time. This work could represent a first attempt in de...

  8. The Cargo

    DEFF Research Database (Denmark)

    Birch, Thomas; Charlton, Michael F.; Biggs, Lynn

    2014-01-01

    The Gresham ship was carrying a substantial cargo of different metals when she sank, representing a considerable financial loss. Reports record that some of that material recovered in 1846 included 2700 tin ingots, lead pigs and iron bars (British Archaeological Association, 1847, 361). The excav...

  9. Determinan Pilihan Pelanggan Terhadap Layanan Cargo Pada PT. Garuda Indonesia Cabang Makassar

    OpenAIRE

    RESPATI., TRIADHI

    2012-01-01

    2012 Penelitian ini bertujuan untuk menganalisis perbedaan pilihan pelanggan terhadap layanan cargo dan memperoleh faktor perbedaan dalam keputusan pilihan pelanggan terhadap layanan cargo. Sedangkan metode analisis yang digunakan adalah analisis deskriptif, analisis kuantitatif dan uji hipotesis. Berdasarkan hasil analisis perbedaan pilihan pelanggan layanan cargo dari masing-masing perusahaan cargo (GIA, Lion Air, Sriwijaya Air dan PT. Wings Air) ternyata ada perbedaan yang signifikan...

  10. Application of x rays to nonintrusive inspection: an assessment

    Science.gov (United States)

    Leach, Eugene R.; Spradling, Michael L.

    1995-05-01

    Two Advanced Research Projects Agency (ARPA) sponsored x-ray nonintrusive inspection system test programs have recently been conducted. A high energy x-ray system designed to inspect air-sea-land intermodal cargo containers and their contents was tested at the Nonintrusive Inspection Technology Testbed (NITT) located in the Port of Tacoma, Washington and a low energy x-ray system designed primarily to examine empty tractor trailer vehicles was tested at the Commercial Inspection Border Crossing Facility at Otay Mesa, California. Both test programs involved the use of a Red/Blue/Silver Team test concept and were conducted in accordance with test protocols. The 'Red Team' which represented the 'smugglers' has the responsibility for preparing cargoes/vehicles for inspection at a location off-site from the inspection facilities. A computer-based algorithm originally developed under contract with ARPA for testing at the NITT was used to randomly select the preparation of the cargoes. The control vehicles were subsequently sent to the test site for x-ray interrogation and analysis. The 'Blue Team' which represented US Customs Service operations analyzed the x- ray images and made recommendation for release/inspection of the control vehicles. The results of the analyses were returned to the Red Team location for evaluation and data compilation by an unbiased observation team. This paper presents discussions related to these x-ray systems' tests including transport techniques, the use of backscatter and transmission imaging for cargo inspection, resolution, analytical tools, and other related considerations for these two systems.

  11. 46 CFR 154.1866 - Cargo hose connection: Transferring cargo.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo hose connection: Transferring cargo. 154.1866... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1866 Cargo hose connection: Transferring cargo. No person may transfer cargo through a cargo hose...

  12. 46 CFR 154.534 - Cargo pumps and cargo compressors.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo pumps and cargo compressors. 154.534 Section 154.534 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES... Equipment Cargo and Process Piping Systems § 154.534 Cargo pumps and cargo compressors. Cargo pumps...

  13. Cargo-cult training

    Science.gov (United States)

    Magueijo, João

    2009-12-01

    Richard Feynman, in one of his famous rants, evoked as a metaphor what he called "cargo-cult science". During the Second World War, the indigenous people of the South Pacific became accustomed to US Air Force planes landing on their islands, invariably bringing a profusion of desirable goods and tasty foods. When the war ended, they were distressed by the discontinuation of this popular service. So, they decided to take action. They cleared elongated patches of land to make them look like runways. They lit wood fires where they had seen electric floodlights guiding in the planes. They built a wooden shack and made a man sit inside with two halves of a coconut on each ear and bamboo bars sticking out like antennas: he was the "air controller". And they waited for the planes to return.

  14. Complexity in human transportation networks: A comparative analysis of worldwide air transportation and global cargo ship movements

    CERN Document Server

    O'Danleyman, Grastivia; Seebens, Hanno; Blasius, Bernd; Brockmann, Dirk

    2011-01-01

    We present a comparative network theoretic analysis of the two largest global transportation networks: The worldwide air-transportation network (WAN) and the global cargoship network (GCSN). We show that both networks exhibit striking statistical similarities despite significant differences in topology and connectivity. Both networks exhibit a discontinuity in node and link betweenness distributions which implies that these networks naturally segragate in two different classes of nodes and links. We introduce a technique based on effective distances, shortest paths and shortest-path trees for strongly weighted symmetric networks and show that in a shortest-path-tree representation the most significant features of both networks can be readily seen. We show that effective shortest-path distance, unlike conventional geographic distance measures, strongly correlates with node centrality measures. Using the new technique we show that network resilience can be investigated more precisely than with contemporary tech...

  15. Supplemental site inspection for Air Force Plant 59, Johnson City, New York, Volume 3: Appendices F-Q

    Energy Technology Data Exchange (ETDEWEB)

    Nashold, B.; Rosenblatt, D.; Hau, J. [and others

    1995-08-01

    This summary describes a Supplemental Site Inspection (SSI) conducted by Argonne National Laboratory (ANL) at Air Force Plant 59 (AFP 59) in Johnson City, New York. All required data pertaining to this project were entered by ANL into the Air Force-wide Installation Restoration Program Information System (IRPIMS) computer format and submitted to an appropriate authority. The work was sponsored by the United States Air Force as part of its Installation Restoration Program (IRP). Previous studies had revealed the presence of contaminants at the site and identified several potential contaminant sources. Argonne`s study was conducted to answer questions raised by earlier investigations. This volume consists of appendices F-Q, which contain the analytical data from the site characterization.

  16. Supplemental site inspection for Air Force Plant 59, Johnson City, New York, Volume 2: Appendices A-E

    Energy Technology Data Exchange (ETDEWEB)

    Nashold, B.; Rosenblatt, D.; Tomasko, D. [and others

    1995-08-01

    This summary describes a Supplemental Site Inspection (SSI) conducted by Argonne National Laboratory (ANL) at Air Force Plant 59 (AFP 59) in Johnson City, New York. All required data pertaining to this project were entered by ANL into the Air Force-wide Installation Restoration Program Information System (IRPIMS) computer format and submitted to an appropriate authority. The work was sponsored by the United States Air Force as part of its Installation Restoration Program (IRP). Previous studies had revealed the presence of contaminants at the site and identified several potential contaminant sources. Argonne`s study was conducted to answer questions raised by earlier investigations. This volume consists of appendices A-E, containing field data and data validation.

  17. Simulation and Optimization of Air Cargo Export Handling System Based on Physical Flow Diagram and Witness Software%基于实体流程图和Witness仿真的航空货运离港系统仿真分析与优化研究

    Institute of Scientific and Technical Information of China (English)

    崔华春; 尹纯建; 贾焜; 石学刚

    2016-01-01

    The air cargo export handling operation is the most important system of the airport ground operations to airlines. And the optimization of the air cargo export handling system is crucial to improve the operation efficiency of air cargo sys-tem. Taking a typical domestic airline hub's air cargo as an example, establishes physical flow diagram based on the work flow of air cargo export handling system, which intuitively ex-hibits the flow of air cargo export handling. On this basis, the bottleneck segment resulting in the low efficiency of air cargo export handling system was obtained by simulation using the Witness software, followed by an optimization to enhance the efficiency of air cargo export handling system. This study plays a significant role to improve the overall operational effi-ciency of the air cargo export handling system. There is a great reference to many other emerging hub airport and small and medium sized airports to optimize their air cargo export handling system.%航空货运离港作业是航空公司地面作业中最重要的环节,航空公司货运离港系统的优化对提高航空货运系统的运作效率至关重要。以国内某典型枢纽机场航空货站为例,根据航空货运离港流程,利用实体流程图对航空货运离港系统流程进行建模,直观地展现货物离港的作业流程。在此基础上,运用Witness软件进行仿真,得到离港系统流程中的瓶颈环节,并对其进行优化,从而提高了航空货运离港系统的效率。以期对其他新兴的枢纽机场以及中小型机场的航空货运离港作业有些许借鉴意义。

  18. PINS Measurements of Explosive Simulants for Cargo Screening

    Energy Technology Data Exchange (ETDEWEB)

    E.H. Seabury

    2008-06-01

    As part of its efforts to prevent the introduction of explosive threats on commercial flights, the Transportation Security Administration (TSL) is evaluating new explosives detection systems (EDSs) for use in air cargo inspection. The TSL has contracted Battelle to develop a new type of explosives simulant to assist in this development. These are designed to mimic the elemental profile (C, H, N, O, etc.) of explosives as well as their densities. Several “neutron in—gamma out” (n,?) techniques have been considered to quantify the elemental profile in these new simulants and the respective explosives. The method chosen by Battelle is Portable Isotopic Neutron Spectroscopy (PINS), developed by Idaho National Laboratory (INL). Battelle wishes to validate that the simulants behave like the explosive threats with this technology. The results of the validation measurements are presented in this report.

  19. 19 CFR 192.14 - Electronic information for outward cargo required in advance of departure.

    Science.gov (United States)

    2010-04-01

    ... vessel cargo is to be laden; (ii) For air cargo, including cargo being transported by Air Express.... The AES Commodity Module already captures the requisite export data, so no new data elements for...-ment (low-risk exporter or other exemption) for any export shipment laden that is not subject to...

  20. Prácticas y representaciones bibliotecarias en la Biblioteca Pública de Buenos Aires: Una lectura del libro de "Cargo y data" (1810-1818 Library practices and representations in the public library of Buenos Aires: a reading of the book of "Cargo y data" (1810-1818

    Directory of Open Access Journals (Sweden)

    Alejandro E. Parada

    2006-06-01

    Full Text Available El artículo estudia, brevemente, las prácticas de gestión bibliotecaria en la Biblioteca Pública de Buenos Aires durante el período 1810-1818. El mismo se basa en un documento existente en el Archivo General de la Nación: el "Libro de cargo y data, o de cuenta corriente de los encargados de los gastos de la Biblioteca Pública formado por el Director de ella Dr. Dn. Luis José Chorroarín en el año 1812". Gracias a esta fuente es posible rastrear la administración y los diversos procesos que permitieron administrar a ese importante establecimiento, una de las primeras creaciones de política cultural de la Revolución de Mayo. De este modo, se abordan varios tópicos de particular interés: ingresos y gastos, personal, venta de ejemplares duplicados y deteriorados, encuadernación de obras, adquisición de libros, mantenimiento edilicio, etc. Entre otras conclusiones se señala la importancia de este tipo de documentos administrativos y burocráticos para conocer la variedad de las prácticas bibliotecarias dentro del marco de la Historia de la Bibliotecología en la Argentina.The article briefly studies the library management practices in the Public Library of Buenos Aires from 1810 to 1818. It is based on a document from the General Archive of the Nation: the "Libro de cargo y data, o de cuenta corriente de los encargados de los gastos de la Biblioteca Pública formado por el Director de ella Dr. Dn. Luis José Chorroarín en el año 1812". Thanks to that source it is possible to track the administration and the different processes that allowed to manage that important place, one of the first creations of cultural politics of the Revolution of May. Thus, several subjects of particular interest are seen here: incomes and expenditures; personnel; selling of duplicate or damaged material; bookbinding; book acquisition; building maintenance; etc. Among several conclusions, the relevance of this type of administrative and bureaucratic

  1. 33 CFR 401.32 - Cargo booms-deck cargo.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Cargo booms-deck cargo. 401.32... OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.32 Cargo booms—deck cargo. (a) Every vessel shall have cargo booms secured in a manner that affords maximum...

  2. Cargo work for maritime operations

    Energy Technology Data Exchange (ETDEWEB)

    House, D.

    2005-07-01

    Previously published as Kemp & Young's Cargo Work, this new edition has been revised and expanded to reflect unit load containerised systems that are now used in the majority of cargo shipping, while retaining the necessary detail on transporting key classes of cargoes safely, efficiently and profitably. The book covers general principles and the latest international regulations that affect all cargo work, including cargo types and key characteristics of a wide range of cargo classes. It also details Roll On-Roll Off cargo handling, containerisation, equipment and offshore supply. Chapter 4 on bulk cargoes contains a section headed: Coal, characteristics, categories and procedures, precautions.

  3. Multipurpose Cargo Transfer Bag

    Science.gov (United States)

    Broyan, James; Baccus, Shelley

    2014-01-01

    The Logistics Reduction (LR) project within the Advanced Exploration Systems (AES) program is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) have been designed such that they can serve the same purpose as a Cargo Transfer Bag, the suitcase-shaped common logistics carrying bag for Shuttle and the International Space Station. After use as a cargo carrier, a regular CTB becomes trash, whereas the MCTB can be unzipped, unsnapped, and unfolded to be reused. Reuse ideas that have been investigated include partitions, crew quarters, solar radiation storm shelters, acoustic blankets, and forward osmosis water processing.

  4. Neutron interrogation system using high gamma ray signature to detect contraband special nuclear materials in cargo

    Science.gov (United States)

    Slaughter, Dennis R.; Pohl, Bertram A.; Dougan, Arden D.; Bernstein, Adam; Prussin, Stanley G.; Norman, Eric B.

    2008-04-15

    A system for inspecting cargo for the presence of special nuclear material. The cargo is irradiated with neutrons. The neutrons produce fission products in the special nuclear material which generate gamma rays. The gamma rays are detecting indicating the presence of the special nuclear material.

  5. 76 FR 4709 - Extension of Agency Information Collection Activity Under OMB Review: Certified Cargo Screening...

    Science.gov (United States)

    2011-01-26

    ... off- airport and includes facilities upstream in the air cargo supply chain, such as shippers, manufacturers, warehousing entities, distributors, third party logistics companies, and Indirect Air Carriers... supply chain to accept, screen, and transport air cargo. The uninterrupted collection of this...

  6. 29 CFR 1918.85 - Containerized cargo operations.

    Science.gov (United States)

    2010-07-01

    ... hookup, anchoring and tie-off techniques, methods of use, and proper methods of equipment inspection and... such container is empty. Methods of identification may include cargo plans, manifests, or markings on... the method of calculation described in paragraph (b)(4)(ii) of this section or by shipping...

  7. X-Ray Scan Detection for Cargo Integrity

    Energy Technology Data Exchange (ETDEWEB)

    Valencia, Juan D.; Miller, Steven D.

    2011-04-18

    ABSTRACT The increase of terrorism and its global impact has made the determination of the contents of cargo containers a necessity. Existing technology allows non-intrusive inspections to determine the contents of a container rapidly and accurately. However, some cargo shipments are exempt from such inspections. Hence, there is a need for a technology that enables rapid and accurate means of detecting whether such containers were non-intrusively inspected. Non-intrusive inspections are most commonly performed utilizing high powered X-ray equipment. The challenge is creating a device that can detect short duration X-ray scans while maintaining a portable, battery powered, low cost, and easy to use platform. The Pacific Northwest National Laboratory (PNNL) has developed a methodology and prototype device focused on this challenge. The prototype, developed by PNNL, is a battery powered electronic device that continuously measures its X-ray and Gamma exposure, calculates the dose equivalent rate, and makes a determination of whether the device has been exposed to the amount of radiation experienced during an X-ray inspection. Once an inspection is detected, the device will record a timestamp of the event and relay the information to authorized personnel via a visual alert, USB connection, and/or wireless communication. The results of this research demonstrate that PNNL’s prototype device can be effective at determining whether a container was scanned by X-ray equipment typically used for cargo container inspections. This paper focuses on laboratory measurements and test results acquired with the PNNL prototype device using several X-ray radiation levels. Keywords: Radiation, Scan, X-ray, Gamma, Detection, Cargo, Container, Wireless, RF

  8. Groupage Cargo Transportation Model

    Directory of Open Access Journals (Sweden)

    Aleksejevs Ruslans

    2016-03-01

    Full Text Available In this work we consider a specific problem of optimal planning of maritime transportation of multiproduct cargo by ships of one (corporate strategy or several (partially corporate strategy companies: the core of the problem consists of the existence of the network of intermediate seaports (i.e. transitional seaports, where for every ship arrived the cargo handling is done, and which are situated between the starting and the finishing seaports. In this work, there are mathematical models built from scratch in the form of multicriteria optimization problem; then the goal attainment method of Gembicki is used for reducing the built models to a one-criterion problem of linear programming.

  9. 14 CFR 121.287 - Carriage of cargo in cargo compartments.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Carriage of cargo in cargo compartments....287 Carriage of cargo in cargo compartments. When cargo is carried in cargo compartments that are..., the cargo must be loaded so as to allow a crewmember to effectively reach all parts of the...

  10. 14 CFR 125.185 - Carriage of cargo in cargo compartments.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Carriage of cargo in cargo compartments... Requirements § 125.185 Carriage of cargo in cargo compartments. When cargo is carried in cargo compartments... during flight, the cargo must be loaded so as to allow a crewmember to effectively reach all parts of...

  11. 49 CFR 1548.9 - Acceptance of cargo.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Acceptance of cargo. 1548.9 Section 1548.9..., DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY INDIRECT AIR CARRIER SECURITY § 1548.9 Acceptance of... program. (b) Refusal to transport. Each indirect air carrier must refuse to offer for transport on...

  12. Compressed Sensing Techniques Applied to Ultrasonic Imaging of Cargo Containers.

    Science.gov (United States)

    López, Yuri Álvarez; Lorenzo, José Ángel Martínez

    2017-01-15

    One of the key issues in the fight against the smuggling of goods has been the development of scanners for cargo inspection. X-ray-based radiographic system scanners are the most developed sensing modality. However, they are costly and use bulky sources that emit hazardous, ionizing radiation. Aiming to improve the probability of threat detection, an ultrasonic-based technique, capable of detecting the footprint of metallic containers or compartments concealed within the metallic structure of the inspected cargo, has been proposed. The system consists of an array of acoustic transceivers that is attached to the metallic structure-under-inspection, creating a guided acoustic Lamb wave. Reflections due to discontinuities are detected in the images, provided by an imaging algorithm. Taking into consideration that the majority of those images are sparse, this contribution analyzes the application of Compressed Sensing (CS) techniques in order to reduce the amount of measurements needed, thus achieving faster scanning, without compromising the detection capabilities of the system. A parametric study of the image quality, as a function of the samples needed in spatial and frequency domains, is presented, as well as the dependence on the sampling pattern. For this purpose, realistic cargo inspection scenarios have been simulated.

  13. Compressed Sensing Techniques Applied to Ultrasonic Imaging of Cargo Containers

    Directory of Open Access Journals (Sweden)

    Yuri Álvarez López

    2017-01-01

    Full Text Available One of the key issues in the fight against the smuggling of goods has been the development of scanners for cargo inspection. X-ray-based radiographic system scanners are the most developed sensing modality. However, they are costly and use bulky sources that emit hazardous, ionizing radiation. Aiming to improve the probability of threat detection, an ultrasonic-based technique, capable of detecting the footprint of metallic containers or compartments concealed within the metallic structure of the inspected cargo, has been proposed. The system consists of an array of acoustic transceivers that is attached to the metallic structure-under-inspection, creating a guided acoustic Lamb wave. Reflections due to discontinuities are detected in the images, provided by an imaging algorithm. Taking into consideration that the majority of those images are sparse, this contribution analyzes the application of Compressed Sensing (CS techniques in order to reduce the amount of measurements needed, thus achieving faster scanning, without compromising the detection capabilities of the system. A parametric study of the image quality, as a function of the samples needed in spatial and frequency domains, is presented, as well as the dependence on the sampling pattern. For this purpose, realistic cargo inspection scenarios have been simulated.

  14. Compressed Sensing Techniques Applied to Ultrasonic Imaging of Cargo Containers

    Science.gov (United States)

    Álvarez López, Yuri; Martínez Lorenzo, José Ángel

    2017-01-01

    One of the key issues in the fight against the smuggling of goods has been the development of scanners for cargo inspection. X-ray-based radiographic system scanners are the most developed sensing modality. However, they are costly and use bulky sources that emit hazardous, ionizing radiation. Aiming to improve the probability of threat detection, an ultrasonic-based technique, capable of detecting the footprint of metallic containers or compartments concealed within the metallic structure of the inspected cargo, has been proposed. The system consists of an array of acoustic transceivers that is attached to the metallic structure-under-inspection, creating a guided acoustic Lamb wave. Reflections due to discontinuities are detected in the images, provided by an imaging algorithm. Taking into consideration that the majority of those images are sparse, this contribution analyzes the application of Compressed Sensing (CS) techniques in order to reduce the amount of measurements needed, thus achieving faster scanning, without compromising the detection capabilities of the system. A parametric study of the image quality, as a function of the samples needed in spatial and frequency domains, is presented, as well as the dependence on the sampling pattern. For this purpose, realistic cargo inspection scenarios have been simulated. PMID:28098841

  15. Acoustic Multipurpose Cargo Transfer Bag

    Science.gov (United States)

    Baccus, Shelley

    2015-01-01

    The Logistics Reduction (LR) project within the Advanced Exploration Systems (AES) program is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) are designed to be the same external volume as a regular cargo transfer bag, the common logistics carrier for the International Space Station. After use as a cargo bag, the MCTB can be unzipped and unfolded to be reused. This Acoustic MCTBs transform into acoustic blankets after the initial logistics carrying objective is complete.

  16. 46 CFR 154.315 - Cargo pump and cargo compressor rooms.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo pump and cargo compressor rooms. 154.315 Section... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Ship Arrangements § 154.315 Cargo pump and cargo compressor rooms. (a) Cargo pump rooms and...

  17. 46 CFR 154.1826 - Opening of cargo tanks and cargo sampling.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Opening of cargo tanks and cargo sampling. 154.1826... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1826 Opening of cargo tanks and cargo sampling. (a) The master shall ensure that each cargo tank opening...

  18. Inspection Database

    Data.gov (United States)

    U.S. Department of Health & Human Services — FDA is disclosing the final inspection classification for inspections related to currently marketed FDA-regulated products. The disclosure of this information is not...

  19. Inspection Database

    Data.gov (United States)

    U.S. Department of Health & Human Services — FDA is disclosing the final inspection classification for inspections related to currently marketed FDA-regulated products. The disclosure of this information is...

  20. Summarized Data of Test Space Heating, Ventilation and Air Conditioning Inspections from the Building Assessment Survey and Evaluation Study

    Science.gov (United States)

    Information on the characteristics of the heating, ventilation, and air conditioning (HVAC) system(s) in the entire BASE building including types of ventilation, equipment configurations, and operation and maintenance issues

  1. 29 CFR 1918.84 - Bulling cargo.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Bulling cargo. 1918.84 Section 1918.84 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.84 Bulling cargo. (a) Bulling cargo shall be done with the bull line led directly from the heel block. However, bulling may be done from...

  2. 78 FR 68784 - Cargo Securing Manuals

    Science.gov (United States)

    2013-11-15

    ... SECURITY Coast Guard 33 CFR Parts 97 and 160, and 46 CFR Part 97 RIN 1625-AA25 Cargo Securing Manuals... proposes requiring cargo securing manuals (CSMs) on vessels of 500 gross tons or more traveling on... Code of Federal Regulations CSAP Cargo safe access plan CSM Cargo Securing Manual CSS Code Code of...

  3. 46 CFR 153.930 - Cargo antidotes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo antidotes. 153.930 Section 153.930 Shipping COAST... Cargo antidotes. No person may operate a tankship that carries a cargo listed in Table 1 unless the tankship has on board the antidotes described for the cargo in the Medical First Aid Guide for Use...

  4. 46 CFR 64.97 - Cargo hose.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Cargo hose. 64.97 Section 64.97 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MARINE PORTABLE TANKS AND CARGO HANDLING SYSTEMS Cargo Handling System § 64.97 Cargo hose. Each hose assembly, consisting of couplings and a...

  5. 46 CFR 151.03-9 - Cargo.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo. 151.03-9 Section 151.03-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-9 Cargo. This term means any liquid, gas or solid having...

  6. 29 CFR 1918.53 - Cargo winches.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Cargo winches. 1918.53 Section 1918.53 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Vessel's Cargo Handling Gear § 1918.53 Cargo winches. (a...) There shall be no load other than the fall and cargo hook assembly on the winch when changing gears on...

  7. Proteomics Characterization of Exosome Cargo

    OpenAIRE

    Schey, Kevin L.; Luther, J. Matthew; Rose, Kristie L

    2015-01-01

    Characterization of exosomal cargo is of significant interest because this cargo can provide clues to exosome biogenesis, targeting, and cellular effects and may be a source of biomarkers for disease diagnosis, prognosis and response to treatment. With recent improvements in proteomics technologies, both qualitative and quantitative characterization of exosomal proteins is possible. Here we provide a brief review of exosome proteomics studies and provide detailed protocols for global qualitat...

  8. Port Security: Container Cargo Control

    Directory of Open Access Journals (Sweden)

    Vladivoj Vlaković

    2006-05-01

    Full Text Available illicittrafficking of threat materials, especially explosives, chemicalsubstances and radioactive or nuclear material. The transportof the threat materials by using sea routes is an advantageto te"orists especially because of the possible use of ship containers.The container is the basis of world trade. It is assumed thatthe world total movement in containers is about 200 millionTEUs ("20-foot equivalent units" per year. The list of materialstransported by containers which should be subject to inspectionwith the aim of reducing the acts of te"orism includes explosives,narcotics, chemical weapons, hazardous chemicalsand radioactive materials.Of special interest is nuclear te"orism. The risk of nuclearte"orism carried out by sub-national groups should be considerednot only in the construction and/or use of nuclear device,but also in possible radioactive contamination of large urbanareas.The system of ship containers control is an essential componentof «smart border» concept. Modem personnel, parcel,vehicle and cargo inspection systems are non-invasive imagingtechniques based on the use of nuclear analytical techniques.The inspection systems use penetrating radiations: hard x-rays(300 keV or more or gamma-rays from radioactive sources(137Cs and 60Co with energies from 600 to 1300 keV that producea high resolution radiograph of the load. Unfortunately,this information is "non-specific" in that it gives no informationon the nature of objects that do not match_ the travel documentsand are not recognized by a visual analysis of the radiographicpicture. Moreover, there are regions of the containerwherex and gamma-ray systems are "blind" due to the high averageatomic number of the objects i"adiated that appear asblack spots in the radiographic image.The systems being developed are based on the use of fast, 14Me V, neutrons with detection of associated a-particle from nuclearreactionbywhichneutrons are produced (d+t>a+n.Jnsuch a way the possibility to

  9. 77 FR 30542 - Air Cargo Screening Fees

    Science.gov (United States)

    2012-05-23

    ... Security Identification Display Area (SIDA) IDs. Another commenter requested that if TSA intends to limit... obtain SIDA IDs were not included in the fee models for this rulemaking because STAs for holders of SIDA... appreciated TSA's recognition that the STAs performed under the SIDA, Commercial Driver's...

  10. Screening Cargo Containers to Remove a Terrorist Threat

    Energy Technology Data Exchange (ETDEWEB)

    Hazi, A

    2005-09-20

    Each year some 48 million cargo containers move between the world's ports. More than 6 million of these enter the U.S., but only about 2 percent are opened and inspected when they arrive at U.S. seaports. The West Coast ports of Los Angeles-Long Beach, Oakland, and Seattle alone process 11,000 containers per day, or about 8 containers per minute. Because of this high traffic volume, U.S. seaports are especially vulnerable to a terrorist attack. Illicit radioactive materials could be hidden in any one of the cargo-filled containers that arrive at U.S. ports. Yet, searching every shipment would be bring legitimate commercial activities to a halt. Improving security at U.S. ports is thus one of the nation's most difficult technical and practical challenges because the systems developed for screening cargo must operate in concert with ongoing seaport activities. Working at this intersection of commerce and national security, Lawrence Livermore researchers are applying their expertise in radiation science and detection to develop improved technologies for detecting hidden radioactive materials. One new technology being designed and tested at the Laboratory is a neutron interrogation system for cargo containers. This system will quickly screen incoming shipments to ensure that nuclear materials such as plutonium and highly enriched uranium (HEU) are not smuggled into the U.S.

  11. Shared Value Potential of Transporting Cargo via Hyperloop

    Directory of Open Access Journals (Sweden)

    Max Werner

    2016-08-01

    Full Text Available This research estimates the shared value created by constructing a hypothetical Hyperloop to transport cargo along 300 km in Northern Germany. Following Porter-Kramer (2011, we identified and evaluated eight factors that create shared value: travel speed, operating costs, safety, noise pollution, air pollution, climate effect/carbon footprint, separation effect/ property efficiency, and maintenance. Using official data compiled by several German institutes and organizations, we conducted comparative analysis to quantify and compare the abovementioned factors for Hyperloop and over-the-road cargo transport in Germany. Then, we monetized the individual and collective benefits of the shared value created by Hyperloop replacing a significant share of cargo transported by truck. Our findings indicate that the hypothetical Hyperloop project in Northern Germany would create €660 to €900 million of shared value annually. Our research method establishes a framework for assessing future transportation projects like Hyperloop, and our findings can be generalized to industrialized nations beyond Germany.

  12. 77 FR 50926 - Security Zones; Certain Dangerous Cargo Vessels, Tampa, FL

    Science.gov (United States)

    2012-08-23

    ... DHS Department of Homeland Security CDC Certain Dangerous Cargo FR Federal Register NPRM Notice of... boarding and inspection of the vessel and persons onboard. The security zones would be enforced from 12:01... the vessel and persons onboard. (4) The Coast Guard will provide notice of the regulated areas...

  13. Opportunity of Constructing a Cargo Terminal – Case Study Brașov International Airport, Romania

    Directory of Open Access Journals (Sweden)

    Gabriel BRĂTUCU

    2017-02-01

    Full Text Available Air transport and especially air cargo transport became ever more important during the last 25 years, with a signifi cant impact upon economic development. Air cargo transport supports regional economic development, provided there is suffi cient local demand for its services. In our study, we have identifi ed signifi cant elements of the impact a cargo terminal at the International Brașov-Ghimbav Airport would have upon local economic development. For this purpose, we have conducted a quantitative market research. We have reached the conclusion that constructing a cargo terminal at the Brașov-Ghimbav Airport is a necessary investment in the current economic context, with an important contribution to the economic development of its surrounding counties. The positive results registered in our study could contribute to improving the economic and fi nancial prospects of Brașov-Ghimbav Airport and attract investors in this project.

  14. A systematic approach to pair secretory cargo receptors with their cargo suggests a mechanism for cargo selection by Erv14.

    Science.gov (United States)

    Herzig, Yonatan; Sharpe, Hayley J; Elbaz, Yael; Munro, Sean; Schuldiner, Maya

    2012-01-01

    The endoplasmic reticulum (ER) is the site of synthesis of secreted and membrane proteins. To exit the ER, proteins are packaged into COPII vesicles through direct interaction with the COPII coat or aided by specific cargo receptors. Despite the fundamental role of such cargo receptors in protein traffic, only a few have been identified; their cargo spectrum is unknown and the signals they recognize remain poorly understood. We present here an approach we term "PAIRS" (pairing analysis of cargo receptors), which combines systematic genetic manipulations of yeast with automated microscopy screening, to map the spectrum of cargo for a known receptor or to uncover a novel receptor for a particular cargo. Using PAIRS we followed the fate of ∼150 cargos on the background of mutations in nine putative cargo receptors and identified novel cargo for most of these receptors. Deletion of the Erv14 cargo receptor affected the widest range of cargo. Erv14 substrates have a wide array of functions and structures; however, they are all membrane-spanning proteins of the late secretory pathway or plasma membrane. Proteins residing in these organelles have longer transmembrane domains (TMDs). Detailed examination of one cargo supported the hypothesis that Erv14 dependency reflects the length rather than the sequence of the TMD. The PAIRS approach allowed us to uncover new cargo for known cargo receptors and to obtain an unbiased look at specificity in cargo selection. Obtaining the spectrum of cargo for a cargo receptor allows a novel perspective on its mode of action. The rules that appear to guide Erv14 substrate recognition suggest that sorting of membrane proteins at multiple points in the secretory pathway could depend on the physical properties of TMDs. Such a mechanism would allow diverse proteins to utilize a few receptors without the constraints of evolving location-specific sorting motifs.

  15. Cargo recognition and cargo-mediated regulation of unconventional myosins.

    Science.gov (United States)

    Lu, Qing; Li, Jianchao; Zhang, Mingjie

    2014-10-21

    Organized motions are hallmarks of living organisms. Such motions range from collective cell movements during development and muscle contractions at the macroscopic scale all the way down to cellular cargo (e.g., various biomolecules and organelles) transportation and mechanoforce sensing at more microscopic scales. Energy required for these biological motions is almost invariably provided by cellular chemical fuels in the form of nucleotide triphosphate. Biological systems have designed a group of nanoscale engines, known as molecular motors, to convert cellular chemical fuels into mechanical energy. Molecular motors come in various forms including cytoskeleton motors (myosin, kinesin, and dynein), nucleic-acid-based motors, cellular membrane-based rotary motors, and so on. The main focus of this Account is one subfamily of actin filament-based motors called unconventional myosins (other than muscle myosin II, the remaining myosins are collectively referred to as unconventional myosins). In general, myosins can use ATP to fuel two types of mechanomotions: dynamic tethering actin filaments with various cellular compartments or structures and actin filament-based intracellular transport. In contrast to rich knowledge accumulated over many decades on ATP hydrolyzing motor heads and their interactions with actin filaments, how various myosins recognize their specific cargoes and whether and how cargoes can in return regulate functions of motors are less understood. Nonetheless, a series of biochemical and structural investigations in the past few years, including works from our own laboratory, begin to shed lights on these latter questions. Some myosins (e.g., myosin-VI) can function both as cellular transporters and as mechanical tethers. To function as a processive transporter, myosins need to form dimers or multimers. To be a mechanical tether, a monomeric myosin is sufficient. It has been shown for myosin-VI that its cellular cargo proteins can play critical roles

  16. 46 CFR 153.908 - Cargo viscosity and melting point information; measuring cargo temperature during discharge...

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo viscosity and melting point information; measuring..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Documents and Cargo Information § 153.908 Cargo viscosity and melting point information; measuring cargo temperature during discharge:...

  17. 46 CFR 154.1810 - Cargo manual.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo manual. 154.1810 Section 154.1810 Shipping COAST... SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1810 Cargo manual. (a) No person... navigable waters of the United States, or a U.S. flag vessel, unless the vessel has on board a cargo...

  18. 46 CFR 153.907 - Cargo information.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo information. 153.907 Section 153.907 Shipping... Information § 153.907 Cargo information. (a) The master shall ensure that the following information for each... process for the vessel. (b) The master shall make sure that the following information for cargoes...

  19. 46 CFR 154.1858 - Cargo hose.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo hose. 154.1858 Section 154.1858 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1858 Cargo hose. The person...

  20. 46 CFR 45.137 - Cargo ports.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Cargo ports. 45.137 Section 45.137 Shipping COAST GUARD....137 Cargo ports. (a) Unless otherwise authorized by the Commandant, the lower edge of any opening for cargo, personnel, machinery access, or similar opening in the side of a ship must be above a line...

  1. 29 CFR 1917.114 - Cargo doors.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Cargo doors. 1917.114 Section 1917.114 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) MARINE TERMINALS Terminal Facilities § 1917.114 Cargo doors. (a) Mechanically operated. (1) Cargo...

  2. 46 CFR 28.885 - Cargo gear.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo gear. 28.885 Section 28.885 Shipping COAST GUARD... Aleutian Trade Act Vessels § 28.885 Cargo gear. (a) The safe working load (SWL) for the assembled gear shall be marked on the heel of each cargo boom, crane, or derrick. These letters and figures are to...

  3. 49 CFR 172.328 - Cargo tanks.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Cargo tanks. 172.328 Section 172.328... SECURITY PLANS Marking § 172.328 Cargo tanks. (a) Providing and affixing identification numbers. Unless a cargo tank is already marked with the identification numbers required by this subpart,...

  4. Cargo transport by several motors

    CERN Document Server

    Zhang, Yunxin

    2010-01-01

    In cells, organelles and vesicles are usually transported by cooperation of several motor proteins, including plus-end directed motor kinesin and minus-end directed motor dynein. Many biophysical models have been constructed to understand the mechanism of this motion. However, so far, the basic principle about it remains unclosed. In this paper, based on the recent experimental results and existing theoretical models, a spider-like model is provided. In this model, each motor is regarded as a bead-spring system. The bead can bind to or unbind from the track stochastically, and step forward or backward with fixed step size L and force dependent transition rates. The spring connects the bead to cargo tightly. At any time, the position of cargo is determined by force balance condition. The obvious characteristics of our model are that, the motors interact with each other and they do not share the external load equally. Our results indicate, the stall force of cargo, under which the mean velocity of cargo vanishe...

  5. Cargo-shell and cargo-cargo couplings govern the mechanics of artificially loaded virus-derived cages

    Science.gov (United States)

    Llauró, Aida; Luque, Daniel; Edwards, Ethan; Trus, Benes L.; Avera, John; Reguera, David; Douglas, Trevor; Pablo, Pedro J. De; Castón, José R.

    2016-04-01

    Nucleic acids are the natural cargo of viruses and key determinants that affect viral shell stability. In some cases the genome structurally reinforces the shell, whereas in others genome packaging causes internal pressure that can induce destabilization. Although it is possible to pack heterologous cargoes inside virus-derived shells, little is known about the physical determinants of these artificial nanocontainers' stability. Atomic force and three-dimensional cryo-electron microscopy provided mechanical and structural information about the physical mechanisms of viral cage stabilization beyond the mere presence/absence of cargos. We analyzed the effects of cargo-shell and cargo-cargo interactions on shell stability after encapsulating two types of proteinaceous payloads. While bound cargo to the inner capsid surface mechanically reinforced the capsid in a structural manner, unbound cargo diffusing freely within the shell cavity pressurized the cages up to ~30 atm due to steric effects. Strong cargo-cargo coupling reduces the resilience of these nanocompartments in ~20% when bound to the shell. Understanding the stability of artificially loaded nanocages will help to design more robust and durable molecular nanocontainers.Nucleic acids are the natural cargo of viruses and key determinants that affect viral shell stability. In some cases the genome structurally reinforces the shell, whereas in others genome packaging causes internal pressure that can induce destabilization. Although it is possible to pack heterologous cargoes inside virus-derived shells, little is known about the physical determinants of these artificial nanocontainers' stability. Atomic force and three-dimensional cryo-electron microscopy provided mechanical and structural information about the physical mechanisms of viral cage stabilization beyond the mere presence/absence of cargos. We analyzed the effects of cargo-shell and cargo-cargo interactions on shell stability after encapsulating two

  6. 46 CFR 153.970 - Cargo transfer piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo transfer piping. 153.970 Section 153.970 Shipping... § 153.970 Cargo transfer piping. The person in charge of cargo transfer shall ensure that: (a) Cargo is transferred to or from a cargo tank only through the tankship's cargo piping system; (b) Vapor not returned...

  7. Experiences with and benefits of the inspection of air-assisted sprayers from the fruit- and winegrowers’ point of view

    Directory of Open Access Journals (Sweden)

    Knoll, M.

    2013-03-01

    Full Text Available Until the 1960s pesticides were applied with a spray gun connected to a long hose or directly to the tank and operated by a worker standing on a platform. This technique was gradually replaced by airassisted sprayers.The purchase of three sprayer test facilities in 1991 signified the start of a new era in pesticide application:• The ejection rate of the individual nozzles as well as the distribution pattern of the liquid could be measured and optimized on a vertical test stand by adjusting the nozzles or adding additional ones. • The ceramic nozzles were replaced by hollow-cone nozzles, which allowed for the first time to calculate the exact amount of liquid per hectare and tree height based on various parameters such as driving speed, spray pressure, number of open nozzles and nozzle output volume. The amount of water was reduced from 500 l/m tree height and hectare to 166 – 100 l. • The efficacy of the pesticides was increased and spray drift reduced, which brings about economic and ecological benefits. • Up to the year 1997 sprayer calibration was optional. Since then, a sprayer calibration in 5-year intervals has become a condition for participation in the South Tyrolean IP-programme. This also facilitates the observance of the GobalGAP control points and Compliance Criteria regarding application equipment.Since 2011 the South Tyrolean sprayer manufacturers and fruit- and winegrowers have been able to measure and optimize the air blast and emission pattern. Thereby we hope to further reduce spray drift and increase the efficacy of the pesticides. A properly calibrated sprayer enables the fruit- and winegrowers to observe more easily the regulations for the distances to residential and public buildings as well as pastures enacted by the South Tyrolean Provincial Government and AGRIOS in 2011. We trust that the South Tyrolean fruit- and winegrowers will have no difficulties in complying with the Directive 2009/128/EC on the

  8. Hospital Inspections

    Data.gov (United States)

    U.S. Department of Health & Human Services — Welcome to hospitalinspections.org, a website run by the Association of Health Care Journalists (AHCJ) that aims to make federal hospital inspection reports easier...

  9. Shared Value Potential of Transporting Cargo via Hyperloop

    OpenAIRE

    Max Werner; Klaus Eissing; Sebastian Langton

    2016-01-01

    This research estimates the shared value created by constructing a hypothetical Hyperloop to transport cargo along 300 km in Northern Germany. Following Porter-Kramer (2011), we identified and evaluated eight factors that create shared value: travel speed, operating costs, safety, noise pollution, air pollution, climate effect/carbon footprint, separation effect/ property efficiency, and maintenance. Using official data compiled by several German institutes and organizations, we conducted com...

  10. 46 CFR 153.957 - Persons in charge of transferring liquid cargo in bulk or cleaning cargo tanks.

    Science.gov (United States)

    2010-10-01

    ... safely transfer liquid cargo in bulk or to safely clean cargo tanks; (2) Each transfer of liquid cargo in... or cleaning cargo tanks. 153.957 Section 153.957 Shipping COAST GUARD, DEPARTMENT OF HOMELAND... transferring liquid cargo in bulk or cleaning cargo tanks. (a) The owner and operator of the vessel, and his...

  11. Cargo-shell and cargo-cargo couplings govern the mechanics of artificially loaded virus-derived cages.

    Science.gov (United States)

    Llauró, Aida; Luque, Daniel; Edwards, Ethan; Trus, Benes L; Avera, John; Reguera, David; Douglas, Trevor; Pablo, Pedro J de; Castón, José R

    2016-04-28

    Nucleic acids are the natural cargo of viruses and key determinants that affect viral shell stability. In some cases the genome structurally reinforces the shell, whereas in others genome packaging causes internal pressure that can induce destabilization. Although it is possible to pack heterologous cargoes inside virus-derived shells, little is known about the physical determinants of these artificial nanocontainers' stability. Atomic force and three-dimensional cryo-electron microscopy provided mechanical and structural information about the physical mechanisms of viral cage stabilization beyond the mere presence/absence of cargos. We analyzed the effects of cargo-shell and cargo-cargo interactions on shell stability after encapsulating two types of proteinaceous payloads. While bound cargo to the inner capsid surface mechanically reinforced the capsid in a structural manner, unbound cargo diffusing freely within the shell cavity pressurized the cages up to ∼30 atm due to steric effects. Strong cargo-cargo coupling reduces the resilience of these nanocompartments in ∼20% when bound to the shell. Understanding the stability of artificially loaded nanocages will help to design more robust and durable molecular nanocontainers.

  12. 75 FR 80765 - Hazardous Materials: Adoption of ASME Code Section XII and the National Board Inspection Code

    Science.gov (United States)

    2010-12-23

    ... Hazardous Materials: Adoption of ASME Code Section XII and the National Board Inspection Code AGENCY... Vessel Code, Section XII for the design, construction, and certification of cargo tank motor vehicles... Code as it applies to the continuing qualification and maintenance of ASME stamped cargo tank...

  13. Proteomics characterization of exosome cargo.

    Science.gov (United States)

    Schey, Kevin L; Luther, J Matthew; Rose, Kristie L

    2015-10-01

    Characterization of exosomal cargo is of significant interest because this cargo can provide clues to exosome biogenesis, targeting, and cellular effects and may be a source of biomarkers for disease diagnosis, prognosis and response to treatment. With recent improvements in proteomics technologies, both qualitative and quantitative characterization of exosomal proteins is possible. Here we provide a brief review of exosome proteomics studies and provide detailed protocols for global qualitative, global quantitative, and targeted quantitative analysis of exosomal proteins. In addition, we provide an example application of a standard global quantitative analysis followed by validation via a targeted quantitative analysis of urine exosome samples from human patients. Advantages and limitations of each method are discussed as well as future directions for exosome proteomics analysis.

  14. Competitiveness of Slovenian Cargo Shipping

    Directory of Open Access Journals (Sweden)

    Milojka Počuča

    2012-10-01

    Full Text Available The paper presents Slovenian cargo shipping, its system oforganisation, ownership, age and value stntcture. It shows theimportance of shipping in the Slovenian overseas trade and itsimpact on the state's balance of payments. The analysis of thecompetitiveness of shipping was made from the viewpoint ofoperation costs and in comparison with the competitiveness ofEU shippers. The paper concludes with a proposal of possiblesystemic solutions which improve the competitiveness of Slovenianshipping.

  15. NWA Cargo Is Granted Additional Cargo Frequencies to China Four all-cargo frequencies per week granted by U.S. Department of Transportation

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ NWA Cargo, the cargo division of Northwest Airlines, will expand its all-cargo freighter service between the United States and China after being awarded four additional frequencies per week by the U.S. Department of Transportation.

  16. Ultrasonic Inspection

    Science.gov (United States)

    1976-01-01

    Automation Industries Inc. has had more than $2 million in contracts to produce innovative equipment for the Apollo program. When Marshall Space Flight Center sought a fast nondestructive way to inspect butt welds in aluminum alloys for spacecraft, the company developed a reliable ultrasonic device using multiple transducers called "delta manipulators" which detect lack of weld penetration not readily seen in radiograph automation. Industry soon adapted the ultrasonic equipment to a unique rail inspection device that saves countless man hours. Device is contained in self propelled railroad cars produced and operated by the company to check old track welds for deterioration.

  17. Communication: Cargo towing by artificial swimmers

    Science.gov (United States)

    Debnath, Debajyoti; Ghosh, Pulak K.; Li, Yunyun; Marchesoni, Fabio; Li, Baowen

    2016-11-01

    An active swimmer can tow a passive cargo by binding it to form a self-propelling dimer. The orientation of the cargo relative to the axis of the active dimer's head is determined by the hydrodynamic interactions associated with the propulsion mechanism of the latter. We show how the tower-cargo angular configuration greatly influences the dimer's diffusivity and, therefore, the efficiency of the active swimmer as a micro-towing motor.

  18. Development of a Cargo Screening Process Simulator: A First Approach

    CERN Document Server

    Siebers, Peer-Olaf; Aickelin, Uwe

    2010-01-01

    The efficiency of current cargo screening processes at sea and air ports is largely unknown as few benchmarks exists against which they could be measured. Some manufacturers provide benchmarks for individual sensors but we found no benchmarks that take a holistic view of the overall screening procedures and no benchmarks that take operator variability into account. Just adding up resources and manpower used is not an effective way for assessing systems where human decision-making and operator compliance to rules play a vital role. Our aim is to develop a decision support tool (cargo-screening system simulator) that will map the right technology and manpower to the right commodity-threat combination in order to maximise detection rates. In this paper we present our ideas for developing such a system and highlight the research challenges we have identified. Then we introduce our first case study and report on the progress we have made so far.

  19. 46 CFR 151.45-4 - Cargo-handling.

    Science.gov (United States)

    2010-10-01

    ... cargo hose connections. (4) Cargo transfer operations for any cargo requiring a PV or safety relief...) All connections for cargo transfer have been made to the vessel's fixed pipeline system. (7) In... control the operations as follows: (1) Supervise the operation of the cargo system valves. (2)...

  20. 46 CFR 154.1834 - Cargo transfer piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo transfer piping. 154.1834 Section 154.1834... piping. The person in charge of cargo transfer shall ensure that cargo is transferred to or from a cargo tank only through the cargo piping system....

  1. 46 CFR 153.910 - Cargo piping plan.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo piping plan. 153.910 Section 153.910 Shipping... Information § 153.910 Cargo piping plan. No person may operate a tankship unless the tankship has a cargo piping plan that: (a) Shows all cargo piping on the tankship; (b) Shows all cargo valving, pumps,...

  2. Nondestructive Testing and Inspection Using Electron Linacs

    Science.gov (United States)

    Reed, William A.

    2012-06-01

    This chapter focuses on the role of electron accelerators that produce X-rays in NDT applications and emphasizes topics of interest to those using accelerator-based inspection products. In addition, it highlights the developments in digital detector technology that have become the precursor to more sophisticated digital radiography and computed tomography applications as well as the emerging security inspection market. Because the demand for accelerators for cargo inspection has vastly exceeded all other industrial NDT applications, this market segment, its special requirements, and future trends are comprehensively discussed. Accelerator systems that are specifically designed to produce neutrons can also be used for some of the same applications, but these are covered in Chapter 6.

  3. Customs Inspection

    Science.gov (United States)

    1977-05-01

    required, for the per- DASDD9-%M) ii the single point of contact for formance of customs inspection functions. customs inspecion matters .in the Office...STATUS Onfdlt dotl. member of Rr": 21 DATE if officer of corporation . slu title) ATP OoM 6A N-7s) PtavIoux MuITUONs MAY BE UN&D Figure l-9. Reld.. and...grips. Commonly called HW-4. Serial number over 300,000 denotes the in- corporation of modified hammer safety components. Model HW-5T Double Action

  4. Characterizing the composition of molecular motors on moving axonal cargo using "cargo mapping" analysis.

    Science.gov (United States)

    Neumann, Sylvia; Campbell, George E; Szpankowski, Lukasz; Goldstein, Lawrence S B; Encalada, Sandra E

    2014-10-30

    Understanding the mechanisms by which molecular motors coordinate their activities to transport vesicular cargoes within neurons requires the quantitative analysis of motor/cargo associations at the single vesicle level. The goal of this protocol is to use quantitative fluorescence microscopy to correlate ("map") the position and directionality of movement of live cargo to the composition and relative amounts of motors associated with the same cargo. "Cargo mapping" consists of live imaging of fluorescently labeled cargoes moving in axons cultured on microfluidic devices, followed by chemical fixation during recording of live movement, and subsequent immunofluorescence (IF) staining of the exact same axonal regions with antibodies against motors. Colocalization between cargoes and their associated motors is assessed by assigning sub-pixel position coordinates to motor and cargo channels, by fitting Gaussian functions to the diffraction-limited point spread functions representing individual fluorescent point sources. Fixed cargo and motor images are subsequently superimposed to plots of cargo movement, to "map" them to their tracked trajectories. The strength of this protocol is the combination of live and IF data to record both the transport of vesicular cargoes in live cells and to determine the motors associated to these exact same vesicles. This technique overcomes previous challenges that use biochemical methods to determine the average motor composition of purified heterogeneous bulk vesicle populations, as these methods do not reveal compositions on single moving cargoes. Furthermore, this protocol can be adapted for the analysis of other transport and/or trafficking pathways in other cell types to correlate the movement of individual intracellular structures with their protein composition. Limitations of this protocol are the relatively low throughput due to low transfection efficiencies of cultured primary neurons and a limited field of view available for

  5. 49 CFR 1544.202 - Persons and property onboard an all-cargo aircraft.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Persons and property onboard an all-cargo aircraft. 1544.202 Section 1544.202 Transportation Other Regulations Relating to Transportation (Continued... SECURITY: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.202 Persons and property onboard an...

  6. 49 CFR 1549.101 - Acceptance, screening, and transfer of cargo.

    Science.gov (United States)

    2010-10-01

    ... approved by TSA, an indirect air carrier under 49 CFR part 1548, an aircraft operator under part 1544, or a... onboard an aircraft of any unauthorized explosives, incendiaries, and other destructive substances or items in cargo onboard an aircraft, as provided in the facility's security program. (b) Screening...

  7. 76 FR 5586 - California State Motor Vehicle and Nonroad Engine Pollution Control Standards; Mobile Cargo...

    Science.gov (United States)

    2011-02-01

    ... Equipment). CARB's Mobile Cargo Handling Equipment requirements are designed to use best available control... Alexander at (202) 343-9540, to learn if a hearing will be held or may check the following webpage for an... restricted by statute. EPA's Office of Transportation and Air Quality also maintains a webpage that...

  8. 46 CFR 153.977 - Supervision of cargo transfer.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Supervision of cargo transfer. 153.977 Section 153.977 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS... Procedures § 153.977 Supervision of cargo transfer. The person in charge of cargo transfer shall:...

  9. 46 CFR 154.552 - Cargo hose: Compatibility.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo hose: Compatibility. 154.552 Section 154.552 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY... Hose § 154.552 Cargo hose: Compatibility. Liquid and vapor cargo hoses must: (a) Not chemically...

  10. 46 CFR 153.935a - Storage of cargo samples.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Storage of cargo samples. 153.935a Section 153.935a Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS... § 153.935a Storage of cargo samples. (a) The master shall make sure that any cargo samples are stored...

  11. 19 CFR 4.38 - Release of cargo.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Release of cargo. 4.38 Section 4.38 Customs Duties... VESSELS IN FOREIGN AND DOMESTIC TRADES Landing and Delivery of Cargo § 4.38 Release of cargo. (a) No... report which lists those shipments which have been authorized for release. This alternative cargo...

  12. 49 CFR 1548.21 - Screening of cargo.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Screening of cargo. 1548.21 Section 1548.21... cargo. An IAC may only screen cargo for transport on a passenger aircraft under §§ 1544.205 and 1546.205 if the IAC is a certified cargo screening facility as provided in part 1549....

  13. 46 CFR 151.45-6 - Maximum amount of cargo.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Maximum amount of cargo. 151.45-6 Section 151.45-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Operations § 151.45-6 Maximum amount of cargo. (a)...

  14. 19 CFR 4.33 - Diversion of cargo.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Diversion of cargo. 4.33 Section 4.33 Customs... VESSELS IN FOREIGN AND DOMESTIC TRADES Landing and Delivery of Cargo § 4.33 Diversion of cargo. (a) Unlading at other than original port of destination. A vessel may unlade cargo or baggage at an...

  15. 46 CFR 98.30-11 - Cargo pumps.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Cargo pumps. 98.30-11 Section 98.30-11 Shipping COAST..., ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Portable Tanks § 98.30-11 Cargo pumps. No person may operate a cargo pump to transfer a product to or from a portable tank unless the...

  16. 46 CFR 154.500 - Cargo and process piping standards.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo and process piping standards. 154.500 Section 154... Equipment Cargo and Process Piping Systems § 154.500 Cargo and process piping standards. The cargo liquid and vapor piping and process piping systems must meet the requirements in §§ 154.503 through...

  17. 46 CFR 153.251 - Independent cargo tanks.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Independent cargo tanks. 153.251 Section 153.251... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Tanks § 153.251 Independent cargo tanks. All independent cargo tank must meet § 38.05-10 (a)(1), (b), (d),...

  18. 46 CFR 151.13-5 - Cargo segregation-tanks.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo segregation-tanks. 151.13-5 Section 151.13-5... CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Cargo Segregation § 151.13-5 Cargo segregation—tanks. (a... symbols used in lines 1 and 2, in order, under the tank segregation column of Table 151.05....

  19. 46 CFR 105.20-3 - Cargo tanks.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Cargo tanks. 105.20-3 Section 105.20-3 Shipping COAST... VESSELS DISPENSING PETROLEUM PRODUCTS Specific Requirements-Cargo Tanks § 105.20-3 Cargo tanks. (a) Construction and Materials. (1) The cargo tanks must be constructed of iron, steel, copper, nickel...

  20. 46 CFR 154.412 - Cargo tank corrosion allowance.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo tank corrosion allowance. 154.412 Section 154.412... Containment Systems § 154.412 Cargo tank corrosion allowance. A cargo tank must be designed with a corrosion...) carries a cargo that corrodes the tank material. Note: Corrosion allowance for independent tank type C...

  1. INSPTRAX - The Inspection Targeting, Planning and Tracking Database

    Data.gov (United States)

    U.S. Environmental Protection Agency — The INSPTRAX System tracks Air, RCRA, and Water inspection targeting, planning and tracking information. It is used by the the Air, RCRA, and Water programs to input...

  2. Design of heavy lift cargo aircraft

    Data.gov (United States)

    National Aeronautics and Space Administration — This is the bird of the skies of the future. The heavy lift cargo aircraft which is currently being developed by me has twice the payload capacity of an Antonov...

  3. Research on probability distribution of port cargo throughput

    Institute of Scientific and Technical Information of China (English)

    SUN Liang; TAN De-rong

    2008-01-01

    In order to more accurately examine developing trends in gross cargo throughput, we have modeled the probability distribution of cargo throughput. Gross cargo throughput is determined by the time spent by cargo ships in the port and the operating efficiency of handling equipment. Gross cargo throughput is the sum of all compound variables determining each aspect of cargo throughput for every cargo ship arriving at the port. Probability distribution was determined using the Wald equation. The results show that the variability of gross cargo throughput primarily depends on the different times required by different cargo ships arriving at the port. This model overcomes the shortcoming of previous models: inability to accurately determine the probability of a specific value of future gross cargo throughput. Our proposed model of cargo throughput depends on the relationship between time required by a cargo ship arriving at the port and the operational capacity of handling equipment at the port. At the same time, key factors affecting gross cargo throughput are analyzed. In order to test the efficiency of the model, the cargo volume of a port in Shandong Province was used as an example. In the case study the actual results matched our theoretical analysis.

  4. Uncertainty Quantification for Cargo Hold Fires

    CERN Document Server

    DeGennaro, Anthony M; Martinelli, Luigi; Rowley, Clarence W

    2015-01-01

    The purpose of this study is twofold -- first, to introduce the application of high-order discontinuous Galerkin methods to buoyancy-driven cargo hold fire simulations, second, to explore statistical variation in the fluid dynamics of a cargo hold fire given parameterized uncertainty in the fire source location and temperature. Cargo hold fires represent a class of problems that require highly-accurate computational methods to simulate faithfully. Hence, we use an in-house discontinuous Galerkin code to treat these flows. Cargo hold fires also exhibit a large amount of uncertainty with respect to the boundary conditions. Thus, the second aim of this paper is to quantify the resulting uncertainty in the flow, using tools from the uncertainty quantification community to ensure that our efforts require a minimal number of simulations. We expect that the results of this study will provide statistical insight into the effects of fire location and temperature on cargo fires, and also assist in the optimization of f...

  5. Security inspection in ports by anomaly detection using hyperspectral imaging technology

    Science.gov (United States)

    Rivera, Javier; Valverde, Fernando; Saldaña, Manuel; Manian, Vidya

    2013-05-01

    Applying hyperspectral imaging technology in port security is crucial for the detection of possible threats or illegal activities. One of the most common problems that cargo suffers is tampering. This represents a danger to society because it creates a channel to smuggle illegal and hazardous products. If a cargo is altered, security inspections on that cargo should contain anomalies that reveal the nature of the tampering. Hyperspectral images can detect anomalies by gathering information through multiple electromagnetic bands. The spectrums extracted from these bands can be used to detect surface anomalies from different materials. Based on this technology, a scenario was built in which a hyperspectral camera was used to inspect the cargo for any surface anomalies and a user interface shows the results. The spectrum of items, altered by different materials that can be used to conceal illegal products, is analyzed and classified in order to provide information about the tampered cargo. The image is analyzed with a variety of techniques such as multiple features extracting algorithms, autonomous anomaly detection, and target spectrum detection. The results will be exported to a workstation or mobile device in order to show them in an easy -to-use interface. This process could enhance the current capabilities of security systems that are already implemented, providing a more complete approach to detect threats and illegal cargo.

  6. Cargo binding to Atg19 unmasks additional Atg8 binding sites to mediate membrane-cargo apposition during selective autophagy.

    Science.gov (United States)

    Sawa-Makarska, Justyna; Abert, Christine; Romanov, Julia; Zens, Bettina; Ibiricu, Iosune; Martens, Sascha

    2014-05-01

    Autophagy protects cells from harmful substances such as protein aggregates, damaged mitochondria and intracellular pathogens, and has been implicated in a variety of diseases. Selectivity of autophagic processes is mediated by cargo receptors that link cargo to Atg8 family proteins on the developing autophagosomal membrane. To avoid collateral degradation during constitutive autophagic pathways, the autophagic machinery must not only select cargo but also exclude non-cargo material. Here we show that cargo directly activates the cargo receptor Atg19 by exposing multiple Atg8 binding sites. Furthermore, Atg19 mediates tight apposition of the cargo and Atg8-coated membranes in a fully reconstituted system. These properties are essential for the function of Atg19 during selective autophagy in vivo. Our results suggest that cargo receptors contribute to tight membrane bending of the isolation membrane around the cargo.

  7. Motility states in bidirectional cargo transport

    CERN Document Server

    Klein, Sarah; Santen, Ludger

    2015-01-01

    Intracellular cargos which are transported by molecular motors move stochastically along cytoskeleton filaments. In particular for bidirectionally transported cargos it is an open question whether the characteristics of their motion can result from pure stochastic fluctuations or whether some coordination of the motors is needed. The results of a mean-field model of cargo-motors dynamics, which was proposed by M\\"uller et al.[1] suggest the existence of high motility states which would result from a stochastic tug-of-war. Here we analyze a non-mean field extension of their model, that takes explicitly the position of each motor into account. We find that high motility states then disappear. We consider also a mutual motor-motor activation, as an explicit mechanism of motor coordination. We show that the results of the mean-field model are recovered only in case of a strong motor-motor activation in the limit of a high number of motors.

  8. Fluctuation effects in bidirectional cargo transport

    CERN Document Server

    Klein, Sarah; Santen, Ludger

    2014-01-01

    We discuss a theoretical model for bidirectional cargo transport in biological cells, which is driven by teams of molecular motors and subject to thermal fluctuations. The model describes explicitly the directed motion of the molecular motors on the filament. The motor-cargo coupling is implemented via linear springs. By means of extensive Monte Carlo simulations we show that the model describes the experimentally observed regimes of anomalous diffusion, i.e. subdiffusive behavior at short times followed by superdiffusion at intermediate times. The model results indicate that subdiffuse regime is induced by thermal fluctuations while the superdiffusive motion is generated by correlations of the motors' activity. We also tested the efficiency of bidirectional cargo transport in crowded areas by measuring its ability to pass barriers with increased viscosity. Our results show a remarkable gain of efficiency for high viscosities.

  9. Development of the Latvian scheme for energy auditing of buildings and inspection of boilers and air-conditioning systems. Final report institutional set-up

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-12-01

    To implement EU directive 93/76/EEC on reduction of carbon dioxide emission by increasing energy efficiency and EU directive 2002/91/EC on building energy efficiency, Latvia must establish and institutional scheme and define all the organisations involved. From a general perspective the institutional scheme must as a minimum include the following four key players: the administrator, the operating unit, the auditors or independent experts, and finally the client. Furthermore, institutions dealing with financing of energy efficiency improvement activities, training and certification of experts, information about auditing and energy efficiency etc. need to be involved. At present there is no governmental or private Latvian organisation that could fully rearrange and assume the duties of an energy audit scheme secretariat. It is therefore recommended initially to place the secretariat as a separate, new unit within the Ministry of Economy, financed by the Ministry of Economy, with the intention of establishing at a later stage (after e.g. 5 years) a separate, new agency, an Energy Efficiency Agency partly financed by the incomes from the energy audit and boiler inspection schemes. The Secretariat should, both in its initial phase and later, assign the tasks of training, information campaigns, quality assurance and evaluation to external organisations. (BA)

  10. An energetic inspection of air conditioning systems in non-residential buildings according to paragraph 12 of the Energy Saving Ordinance; Energetische Inspektion von Klimaanlagen in Nichtwohngebaeuden nach paragraph 12 der Energieeinsparverordnung EnEV

    Energy Technology Data Exchange (ETDEWEB)

    Schaedlich, Sylvia; Trogisch, Achim

    2011-07-01

    The authors of the book under consideration report on the energy inspection according to paragraph 12 of the Energy Saving Ordinance. The possibilities and limits of the energy inspection as well as the legal fundamentals and calculation methods are presented.

  11. 46 CFR 153.440 - Cargo temperature sensors.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo temperature sensors. 153.440 Section 153.440 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS... Temperature Control Systems § 153.440 Cargo temperature sensors. (a) Except as prescribed in paragraph (c)...

  12. 33 CFR 157.23 - Cargo and ballast system information.

    Science.gov (United States)

    2010-07-01

    ... CARRYING OIL IN BULK Design, Equipment, and Installation § 157.23 Cargo and ballast system information. (a... automatic and manual operation of the cargo and ballast system in the vessel. (b) The format and information... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Cargo and ballast...

  13. 46 CFR 153.972 - Connecting a cargo hose.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Connecting a cargo hose. 153.972 Section 153.972 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Cargo...

  14. 19 CFR 4.36 - Delayed discharge of cargo.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Delayed discharge of cargo. 4.36 Section 4.36... TREASURY VESSELS IN FOREIGN AND DOMESTIC TRADES Landing and Delivery of Cargo § 4.36 Delayed discharge of cargo. (a) When pursuant to section 457, Tariff Act of 1930, customs officers are placed on a...

  15. 46 CFR 98.25-80 - Cargo hose.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Cargo hose. 98.25-80 Section 98.25-80 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS SPECIAL CONSTRUCTION, ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Anhydrous Ammonia in Bulk §...

  16. 46 CFR 154.310 - Cargo piping systems.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo piping systems. 154.310 Section 154.310 Shipping... Arrangements § 154.310 Cargo piping systems. Cargo liquid or vapor piping must: (a) Be separated from other piping systems, except where an interconnection to inert gas or purge piping is required by §...

  17. 46 CFR 153.283 - Valving for cargo piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Valving for cargo piping. 153.283 Section 153.283... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Piping Systems and Cargo Handling Equipment § 153.283 Valving for cargo piping. (a) Except as described in...

  18. 46 CFR 154.356 - Cargo emergency jettisoning piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo emergency jettisoning piping. 154.356 Section 154.356 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES... Equipment Ship Arrangements § 154.356 Cargo emergency jettisoning piping. Emergency jettisoning piping...

  19. 46 CFR 154.1844 - Cargo tanks: Filling limits.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo tanks: Filling limits. 154.1844 Section 154.1844... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1844 Cargo tanks... cargo tank is not loaded: (1) More than 98 percent liquid full; or (2) In excess of the...

  20. 46 CFR 151.15-10 - Cargo gauging devices.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo gauging devices. 151.15-10 Section 151.15-10... CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Tanks § 151.15-10 Cargo gauging devices. This section contains definitions and requirements for types of gauging devices specified in Table 151.05. (a)...

  1. 46 CFR 151.50-5 - Cargoes having toxic properties.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargoes having toxic properties. 151.50-5 Section 151.50... BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Special Requirements § 151.50-5 Cargoes having... transporting liquids having a Reid vapor pressure exceeding 14 pounds per square inch absolute or vented at...

  2. 46 CFR 151.25-2 - Cargo handling space.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed...

  3. Stochastic Movement of Multiple Motor Transported Cargo

    Science.gov (United States)

    Ando, David; Gopinathan, Ajay; Xu, Jing

    2015-03-01

    Experimental observations of cargo position during transport by multiple motors are determined by several coupled stochastic processes. During collective transport, each motor can transition between multiple kinetic states, with the state of each motor influencing the states of the others via mechanical coupling through a common cargo. We measured the motion of a micron sized bead as it is transported by two kinesin motors along a single microtubule track, focusing on cargo displacements which are both axial and transverse to the microtubule. We model the effects of inter-motor interference and the state of each motor throughout time, and back out motor properties using a systematic comparison of experimental observations with simulated model traces over a wide parameter space. Our model captures a surface-associated mode of kinesin, which is only accessible via inter-motor interference in groups, in which kinesin diffuses along the microtubule surface and rapidly ``hops'' between protofilaments without dissociating from the microtubule. This enhances local exploration of the microtubule surface, possibly enabling cellular cargos to overcome macromolecular crowding and to navigate obstacles along micro- tubule tracks without sacrificing overall travel distance.

  4. Linking molecular motors to membrane cargo

    NARCIS (Netherlands)

    A.S. Akhmanova (Anna); J.A. Hammer (John)

    2010-01-01

    textabstractThree types of motors, myosins, kinesins, and cytoplasmic dynein, cooperate to transport intracellular membrane organelles. Transport of each cargo is determined by recruitment of specific sets of motors and their regulation. Targeting of motors to membranes often depends on the formatio

  5. Cargo Integration Products for External Release

    Science.gov (United States)

    Sills, Joel W.

    2008-01-01

    This document consists of a listing of integration products by function: Reconfiguration Engineering, Payload Interface Requirements, and Cargo Integration Analysis. The products may be accessed from, the Flight Operation and Integration Office page, i.e. http://sspweb.jsc.nasa.gov/.

  6. Assembly and Mechanical Properties of the Cargo-Free and Cargo-Loaded Bacterial Nanocompartment Encapsulin.

    Science.gov (United States)

    Snijder, Joost; Kononova, Olga; Barbu, Ioana M; Uetrecht, Charlotte; Rurup, W Frederik; Burnley, Rebecca J; Koay, Melissa S T; Cornelissen, Jeroen J L M; Roos, Wouter H; Barsegov, Valeri; Wuite, Gijs J L; Heck, Albert J R

    2016-08-08

    Prokaryotes mostly lack membranous compartments that are typical of eukaryotic cells, but instead, they have various protein-based organelles. These include bacterial microcompartments like the carboxysome and the virus-like nanocompartment encapsulin. Encapsulins have an adaptable mechanism for enzyme packaging, which makes it an attractive platform to carry a foreign protein cargo. Here we investigate the assembly pathways and mechanical properties of the cargo-free and cargo-loaded nanocompartments, using a combination of native mass spectrometry, atomic force microscopy and multiscale computational molecular modeling. We show that encapsulin dimers assemble into rigid single-enzyme bacterial containers. Moreover, we demonstrate that cargo encapsulation has a mechanical impact on the shell. The structural similarity of encapsulins to virus capsids is reflected in their mechanical properties. With these robust mechanical properties encapsulins provide a suitable platform for the development of nanotechnological applications.

  7. Aspects of Inspection Planning

    DEFF Research Database (Denmark)

    Faber, M. H.; Sørensen, John Dalsgaard

    2000-01-01

    Inspection planning for systems is considered with special emphasis to the effect of the quality of inspections on the system reliability and the probability of repair. Inspection quality is described and discussed in terms of inspection reliability and inspection coverage where the latter is set...... in relation to the correlation between the failure modes of the considered system. The inspection planning problem is described in general terms taking basis in the Bayesian decision theory. Practical applicable approaches are derived from the more general but also more involving formulations. The theoretical...... framework for updating of the reliability of components and systems on the basis of inspection results is outlined. Systems representative for inspection planning of different engineering systems subjected to typical deterioration processes are presented. Numerical simulation studies are performed...

  8. Econometric Analysis on the Effectiveness across Port State Control Regimes:What are the Areas of Improvement for Inspections?

    Institute of Scientific and Technical Information of China (English)

    Sabine Knapp; Philip Hans Franses

    2007-01-01

    <正>The lack of trust in the maritime industry has led to a variety of inspections onboard ships that are performed in the name of safety.This article is based on a combined dataset of port state control inspections and casualties for the time period 1999 to 2004 and identifies areas for improvement of port state control inspections.We use binary logistic regression on a dataset which is constructed of twin ships in order to better filter out effects associated with inspection variables such as deficiencies,time in-between inspections,detention or who inspected the vessel while incorporating a summary of ship’s inspection hi story.The model s suggest that there is some 1ack of fol1ow up on recti f- ying deficiencies that have been found during inspections.In addition, the results identify that the main areas of improvement of inspections are within the ISM code(International Safety Management Code) for tankers and general cargo vessels,ship and cargo operations and machinery and propulsion.In addition,the variable indicating detention does not seem to be significant for most models and time in-between inspections only seems to be relevant for serious casualties but not very serious casualties.

  9. Electronic Inspection of Beef

    Science.gov (United States)

    Anselmo, Victor J.; Gammell, Paul M.; Clark, Jerry

    1987-01-01

    Two proposed methods for grading beef quality based on inspection by electronic equipment: one method uses television camera to generate image of a cut of beef as customer sees it; other uses ultrasonics to inspect live animal or unsliced carcasses. Both methods show promise for automated meat inspection.

  10. Discharging Part of LNG Liquid Cargo Handling Simulator

    Directory of Open Access Journals (Sweden)

    Zhen-Zhou Yang

    2013-09-01

    Full Text Available With the development of the national economy, it is important to develop LNG (Liquefied Natural Gas liquid cargo handling simulator. In this paper, the discharging part of Liquid Cargo Handling Simulator of LNG Carriers is developed by Visual Basic. The system includes 5 major forms and 3 mathematical models such as cargo pump model, the pressure and temperature model of the LNG vapour in the cargo tank and the liquid level model. The system can complete the unloading task. The system has become a preliminary model of LNG liquid cargo handlings simulator training.

  11. Industrial applications of automated X-ray inspection

    Science.gov (United States)

    Shashishekhar, N.

    2015-03-01

    Many industries require that 100% of manufactured parts be X-ray inspected. Factors such as high production rates, focus on inspection quality, operator fatigue and inspection cost reduction translate to an increasing need for automating the inspection process. Automated X-ray inspection involves the use of image processing algorithms and computer software for analysis and interpretation of X-ray images. This paper presents industrial applications and illustrative case studies of automated X-ray inspection in areas such as automotive castings, fuel plates, air-bag inflators and tires. It is usually necessary to employ application-specific automated inspection strategies and techniques, since each application has unique characteristics and interpretation requirements.

  12. Cargo adaptors: structures illuminate mechanisms regulating vesicle biogenesis.

    Science.gov (United States)

    Paczkowski, Jon E; Richardson, Brian C; Fromme, J Christopher

    2015-07-01

    Cargo adaptors sort transmembrane protein cargos into nascent vesicles by binding directly to their cytosolic domains. Recent studies have revealed previously unappreciated roles for cargo adaptors and regulatory mechanisms governing their function. The adaptor protein (AP)-1 and AP-2 clathrin adaptors switch between open and closed conformations that ensure they function at the right place at the right time. The exomer cargo adaptor has a direct role in remodeling the membrane for vesicle fission. Several different cargo adaptors functioning in distinct trafficking pathways at the Golgi are similarly regulated through bivalent binding to the ADP-ribosylation factor 1 (Arf1) GTPase, potentially enabling regulation by a threshold concentration of Arf1. Taken together, these studies highlight that cargo adaptors do more than just adapt cargos.

  13. Approximations in Inspection Planning

    DEFF Research Database (Denmark)

    Engelund, S.; Sørensen, John Dalsgaard; Faber, M. H.

    2000-01-01

    Planning of inspections of civil engineering structures may be performed within the framework of Bayesian decision analysis. The effort involved in a full Bayesian decision analysis is relatively large. Therefore, the actual inspection planning is usually performed using a number of approximations....... One of the more important of these approximations is the assumption that all inspections will reveal no defects. Using this approximation the optimal inspection plan may be determined on the basis of conditional probabilities, i.e. the probability of failure given no defects have been found...... by the inspection. In this paper the quality of this approximation is investigated. The inspection planning is formulated both as a full Bayesian decision problem and on the basis of the assumption that the inspection will reveal no defects....

  14. Cargo transportation by two species of motor protein.

    Science.gov (United States)

    Zhang, Yunxin

    2013-05-01

    The cargo motion in living cells transported by two species of motor protein with different intrinsic directionalities is discussed in this study. Similarly to single motor movement, the cargo steps forward and backward along a microtubule stochastically. Recent experiments found that cargo transportation by two motor species has a memory; it does not change its direction as frequently as expected, which means that its forward and backward step rates depend on its previous motion trajectory. By assuming that the cargo has only the least possible memory, i.e., its step direction depends only on the direction of its last step, two cases of cargo motion are analyzed in detail in this study: (I) cargo motion under constant external load, and (II) cargo motion in one fixed optical trap. Due to the existence of memory, in the first case, the cargo can keep moving in the same direction for a long distance. In the second case, the cargo will oscillate in the trap. The oscillation period decreases and the oscillation amplitude increases with increasing forward step rate of the motor, but both of them decrease with increasing trap stiffness. The most likely location of the cargo, where the probability of finding the oscillating cargo is maximum, may be the same as or may be different from the trap center, which depends on the step rates of the two motor species. Meanwhile, if the motors are robust, i.e., their forward to backward step rate ratios are high, there may be two such most likely locations, located one on each side of the trap center. The probability of finding the cargo in a given location, the probability of the cargo being in forward or backward motion, and various mean first passage times of the cargo to a given location or a given state are also analyzed.

  15. Development of Decision Making Algorithm for Control of Sea Cargo Containers by ``TAGGED'' Neutron Method

    Science.gov (United States)

    Anan'ev, A. A.; Belichenko, S. G.; Bogolyubov, E. P.; Bochkarev, O. V.; Petrov, E. V.; Polishchuk, A. M.; Udaltsov, A. Yu.

    2009-12-01

    Nowadays in Russia and abroad there are several groups of scientists, engaged in development of systems based on "tagged" neutron method (API method) and intended for detection of dangerous materials, including high explosives (HE). Particular attention is paid to possibility of detection of dangerous objects inside a sea cargo container. Energy gamma-spectrum, registered from object under inspection is used for determination of oxygen/carbon and nitrogen/carbon chemical ratios, according to which dangerous object is distinguished from not dangerous one. Material of filled container, however, gives rise to additional effects of rescattering and moderation of 14 MeV primary neutrons of generator, attenuation of secondary gamma-radiation from reactions of inelastic neutron scattering on objects under inspection. These effects lead to distortion of energy gamma-response from examined object and therefore prevent correct recognition of chemical ratios. These difficulties are taken into account in analytical method, presented in the paper. Method has been validated against experimental data, obtained by the system for HE detection in sea cargo, based on API method and developed in VNIIA. Influence of shielding materials on results of HE detection and identification is considered. Wood and iron were used as shielding materials. Results of method application for analysis of experimental data on HE simulator measurement (tetryl, trotyl, hexogen) are presented.

  16. Cargo-mix optimization in Liner Shipping

    DEFF Research Database (Denmark)

    Christensen, Jonas Mark; Pacino, Dario; Fonseca, Joao Filipe Paiva

    , it is hard tomotivate companies to pay for cleaner transport since transportation is not visible to end customers,and therefore cannot justify a higher cost. Hence, optimization may be one of the few options forlimiting CO2 emission of international trade. A possible direction is to focus on vessels...... composition available in the different portsmight not be suitable for the full utilization of the vessel. The focus of our work is the analysis ofvessels’ cargo-mix, in particular finding what cargo composition is needed for a vessel to maximizeits utilization on a given service. Such a model can have various...... applications ranging from drivingrate prices, improving fleet composition and network design ((Christiansen et al., 2007; Reinhardtand Pisinger, 2012; Brouer et al., 2014))....

  17. A Review of Cargo Handling Equipment

    Science.gov (United States)

    1971-10-01

    surge, and sway). If, for example, only heave compensation is employed, i.e., one constraint, then the cargo may swing in a pendulous manner and the...pendulous mass as well as lack of heave compensation . One proposed method for overcoming the heave compensation problem is to tie the helicopter to the...deck. Further, any method which does not use the ship as a reference (i.e., not mounted on the ship) must also provide for some type of heave

  18. Basic mechanisms for recognition and transport of synaptic cargos

    Directory of Open Access Journals (Sweden)

    Schlager Max A

    2009-08-01

    Full Text Available Abstract Synaptic cargo trafficking is essential for synapse formation, function and plasticity. In order to transport synaptic cargo, such as synaptic vesicle precursors, mitochondria, neurotransmitter receptors and signaling proteins to their site of action, neurons make use of molecular motor proteins. These motors operate on the microtubule and actin cytoskeleton and are highly regulated so that different cargos can be transported to distinct synaptic specializations at both pre- and post-synaptic sites. How synaptic cargos achieve specificity, directionality and timing of transport is a developing area of investigation. Recent studies demonstrate that the docking of motors to their cargos is a key control point. Moreover, precise spatial and temporal regulation of motor-cargo interactions is important for transport specificity and cargo recruitment. Local signaling pathways – Ca2+ influx, CaMKII signaling and Rab GTPase activity – regulate motor activity and cargo release at synaptic locations. We discuss here how different motors recognize their synaptic cargo and how motor-cargo interactions are regulated by neuronal activity.

  19. A mechanism for retromer endosomal coat complex assembly with cargo.

    Science.gov (United States)

    Harrison, Megan S; Hung, Chia-Sui; Liu, Ting-ting; Christiano, Romain; Walther, Tobias C; Burd, Christopher G

    2014-01-07

    Retromer is an evolutionarily conserved protein complex composed of the VPS26, VPS29, and VPS35 proteins that selects and packages cargo proteins into transport carriers that export cargo from the endosome. The mechanisms by which retromer is recruited to the endosome and captures cargo are unknown. We show that membrane recruitment of retromer is mediated by bivalent recognition of an effector of PI3K, SNX3, and the RAB7A GTPase, by the VPS35 retromer subunit. These bivalent interactions prime retromer to capture integral membrane cargo, which enhances membrane association of retromer and initiates cargo sorting. The role of RAB7A is severely impaired by a mutation, K157N, that causes Charcot-Marie-Tooth neuropathy 2B. The results elucidate minimal requirements for retromer assembly on the endosome membrane and reveal how PI3K and RAB signaling are coupled to initiate retromer-mediated cargo export.

  20. 9 CFR 354.34 - Application for inspection service in official plants; approval.

    Science.gov (United States)

    2010-01-01

    ... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION VOLUNTARY INSPECTION OF RABBITS AND EDIBLE... transfer points. (10) The routes of the edible and inedible products. (11) The location of fresh air inlets... insects. (6) Finish of floors—concrete, brick, mastic material, etc. (7) Drainage—indicate the amount...

  1. 46 CFR 150.160 - Carrying a cargo as an exception to the compatibility chart.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Carrying a cargo as an exception to the compatibility... BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.160 Carrying a cargo as an exception to the compatibility chart. The Operator of a vessel having on board a cargo carried as an exception under §...

  2. 46 CFR 308.517 - Open Cargo Policy, Form MA-300.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Open Cargo Policy, Form MA-300. 308.517 Section 308.517... Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.517 Open Cargo Policy, Form MA-300. The standard form of War Risk Open Cargo, Form MA-300, may be obtained from the American War...

  3. Cargo transportation by two species of motor protein

    CERN Document Server

    Zhang, Yunxin

    2012-01-01

    The cargo motion in living cells transported by two species of motor protein with different intrinsic directionality is discussed in this study. Similar to single motor movement, cargo steps forward and backward along microtubule stochastically. Recent experiments found that, cargo transportation by two motor species has a memory, it does not change its direction as frequently as expected, which means that its forward and backward step rates depends on its previous motion trajectory. By assuming cargo has only the least memory, i.e. its step direction depends only on the direction of its last step, two cases of cargo motion are detailed analyzed in this study: {\\bf (I)} cargo motion under constant external load; and {\\bf (II)} cargo motion in one fixed optical trap. Due to the existence of memory, for the first case, cargo can keep moving in the same direction for a long distance. For the second case, the cargo will oscillate in the trap. The oscillation period decreases and the oscillation amplitude increase...

  4. Column generation approaches to ship scheduling with flexible cargo sizes

    DEFF Research Database (Denmark)

    Brønmo, Geir; Nygreen, Bjørn; Lysgaard, Jens

    2010-01-01

    We present a Dantzig-Wolfe procedure for the ship scheduling problem with flexible cargo sizes. This problem is similar to the well-known pickup and delivery problem with time windows, but the cargo sizes are defined by intervals instead of by fixed values. The flexible cargo sizes have...... consequences for the times used in the ports because both the loading and unloading times depend on the cargo sizes. We found it computationally hard to find exact solutions to the subproblems, so our method does not guarantee to find the optimum over all solutions. To be able to say something about how good...

  5. A Dual-Purpose Ion-Accelerator for Nuclear-Reaction-Based Explosives-and SNM-Detection in Massive Cargo

    CERN Document Server

    Goldberg, M B; Vartsky, D; Bar, D; Böttger, R; Brandis, M; Bromberger, B; Feldman, G; Friedman, E; Heflinger, D; Lauck, R; Löb, S; Maier-Komor, P; Mardor, I; Mor, I; Speidel, K -H; Tittelmeier, K; Weierganz, M

    2010-01-01

    A dual-purpose ion-accelerator concept, capable of serving as radiation source in a versatile, nuclear-reaction-based cargo inspection system, is presented. The system will automatically and reliably detect small, operationally-relevant quantities of concealed explosives and special nuclear materials (SNM). It will be cost-effective, employing largely-common hardware, but different reactions/DAQ-modes. Typical expected throughput is 10-20 aviation containers/hr. PACS: 25.20.Dc; 25.40.Ny; 27.20.+n; 29.27.Fh; 79.77.+g; 89.20.Bb; 89.20.Dd Keywords: Cargo inspection; Nuclear-reaction-based methods; Explosives detection; SNM detection

  6. Large area x-ray detectors for cargo radiography

    Science.gov (United States)

    Bueno, C.; Albagli, D.; Bendahan, J.; Castleberry, D.; Gordon, C.; Hopkins, F.; Ross, W.

    2007-04-01

    Large area x-ray detectors based on phosphors coupled to flat panel amorphous silicon diode technology offer significant advances for cargo radiologic imaging. Flat panel area detectors provide large object coverage offering high throughput inspections to meet the high flow rate of container commerce. These detectors provide excellent spatial resolution when needed, and enhanced SNR through low noise electronics. If the resolution is reduced through pixel binning, further advances in SNR are achievable. Extended exposure imaging and frame averaging enables improved x-ray penetration of ultra-thick objects, or "select-your-own" contrast sensitivity at a rate many times faster than LDAs. The areal coverage of flat panel technology provides inherent volumetric imaging with the appropriate scanning methods. Flat panel area detectors have flexible designs in terms of electronic control, scintillator selection, pixel pitch, and frame rates. Their cost is becoming more competitive as production ramps up for the healthcare, nondestructive testing (NDT), and homeland protection industries. Typically used medical and industrial polycrystalline phosphor materials such as Gd2O2S:Tb (GOS) can be applied to megavolt applications if the phosphor layer is sufficiently thick to enhance x-ray absorption, and if a metal radiator is used to augment the quantum detection efficiency and reduce x-ray scatter. Phosphor layers ranging from 0.2-mm to 1-mm can be "sandwiched" between amorphous silicon flat panel diode arrays and metal radiators. Metal plates consisting of W, Pb or Cu, with thicknesses ranging from 0.25-mm to well over 1-mm can be used by covering the entire area of the phosphor plate. In some combinations of high density metal and phosphor layers, the metal plate provides an intensification of 25% in signal due to electron emission from the plate and subsequent excitation within the phosphor material. This further improves the SNR of the system.

  7. 46 CFR 151.20-10 - Cargo system instrumentation.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo system instrumentation. 151.20-10 Section 151.20-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES... instrumentation. (a) Each tank operated at other than ambient temperature shall be provided with at least...

  8. 46 CFR 154.548 - Cargo piping: Flow capacity.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo piping: Flow capacity. 154.548 Section 154.548... and Process Piping Systems § 154.548 Cargo piping: Flow capacity. Piping with an excess flow valve must have a vapor or liquid flow capacity that is greater than the rated closing flow under § 154.546....

  9. 49 CFR 175.78 - Stowage compatibility of cargo.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Stowage compatibility of cargo. 175.78 Section 175... Loading, Unloading and Handling § 175.78 Stowage compatibility of cargo. (a) For stowage on an aircraft..., Compatibility Group S, explosives are permitted to be transported aboard a passenger aircraft. Only...

  10. 49 CFR 180.405 - Qualification of cargo tanks.

    Science.gov (United States)

    2010-10-01

    ... protection or other appropriate accident damage protection device. (v) A cargo tank may be constructed of.... (l) MC 300, MC 301, MC 302, MC 303, MC 305, MC 306 cargo tank—Rear accident damage protection. (1... accident damage protection device to protect the tank and piping in the event of a rear-end collision...

  11. 46 CFR 154.195 - Aluminum cargo tank: Steel enclosure.

    Science.gov (United States)

    2010-10-01

    ... published in “Rules for Building and Classing Steel Vessels”, 1981. (c) The steel cover for the aluminum... 46 Shipping 5 2010-10-01 2010-10-01 false Aluminum cargo tank: Steel enclosure. 154.195 Section... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction...

  12. Information tecnology and its impact on port cargo distribution businness

    OpenAIRE

    Trampus, Francesca

    2002-01-01

    The IT revolution has dynamised the port cargo business: up-to-date software is needed to optimize operations such as vessel loading, yard planning, equipment flow, gate handling, administration and invoicing and it is also essential for vessel tracking, electronic declaration of cargo and passengers and as a communication platform to all port users.

  13. 76 FR 41278 - Cargo Security Risk Reduction; Public Listening Sessions

    Science.gov (United States)

    2011-07-13

    ... SECURITY Coast Guard Cargo Security Risk Reduction; Public Listening Sessions AGENCY: Coast Guard, DHS..., transfer, and storage of Certain Dangerous Cargo (CDC) in bulk within the U.S. Marine Transportation System....Bergan@uscg.mil . SUPPLEMENTARY INFORMATION: Background In September 2009, the Coast Guard held a...

  14. 46 CFR 98.25-55 - Cargo piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Cargo piping. 98.25-55 Section 98.25-55 Shipping COAST... Cargo piping. (a) Piping shall be of seamless steel meeting the requirements of § 56.60-1 of subchapter F (Marine Engineering) of this chapter. The piping shall be of not less than Schedule 40...

  15. Environmental control of microtubule-based bidirectional cargo-transport

    CERN Document Server

    Klein, Sarah; Santen, Ludger

    2014-01-01

    Inside cells, various cargos are transported by teams of molecular motors. Intriguingly, the motors involved generally have opposite pulling directions, and the resulting cargo dynamics is a biased stochastic motion. It is an open question how the cell can control this bias. Here we develop a model which takes explicitly into account the elastic coupling of the cargo with each motor. We show that bias can be simply controlled or even reversed in a counterintuitive manner via a change in the external force exerted on the cargo or a variation of the ATP binding rate to motors. Furthermore, the superdiffusive behavior found at short time scales indicates the emergence of motor cooperation induced by cargo-mediated coupling.

  16. Signal Station Inspection Reports

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Handwritten reports resulting from detailed inspections of US Army Signal Service Stations, 1871-1889. Features reported included instrument exposure and condition,...

  17. 46 CFR 150.130 - Loading a cargo on vessels carrying cargoes with which it is incompatible.

    Science.gov (United States)

    2010-10-01

    ... it is incompatible. 150.130 Section 150.130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... carrying cargoes with which it is incompatible. Except as described in § 150.160, the person in charge of a... any cargo in table I with which it is incompatible by two barriers such as formed by a: (1)...

  18. Vacuolar transport in tobacco leaf epidermis cells involves a single route for soluble cargo and multiple routes for membrane cargo.

    Science.gov (United States)

    Bottanelli, Francesca; Foresti, Ombretta; Hanton, Sally; Denecke, Jürgen

    2011-08-01

    We tested if different classes of vacuolar cargo reach the vacuole via distinct mechanisms by interference at multiple steps along the transport route. We show that nucleotide-free mutants of low molecular weight GTPases, including Rab11, the Rab5 members Rha1 and Ara6, and the tonoplast-resident Rab7, caused induced secretion of both lytic and storage vacuolar cargo. In situ analysis in leaf epidermis cells indicates a sequential action of Rab11, Rab5, and Rab7 GTPases. Compared with Rab5 members, mutant Rab11 mediates an early transport defect interfering with the arrival of cargo at prevacuoles, while mutant Rab7 inhibits the final delivery to the vacuole and increases cargo levels in prevacuoles. In contrast with soluble cargo, membrane cargo may follow different routes. Tonoplast targeting of an α-TIP chimera was impaired by nucleotide-free Rha1, Ara6, and Rab7 similar to soluble cargo. By contrast, the tail-anchored tonoplast SNARE Vam3 shares only the Rab7-mediated vacuolar deposition step. The most marked difference was observed for the calcineurin binding protein CBL6, which was insensitive to all Rab mutants tested. Unlike soluble cargo, α-TIP and Vam3, CBL6 transport to the vacuole was COPII independent. The results indicate that soluble vacuolar proteins follow a single route to vacuoles, while membrane spanning proteins may use at least three different transport mechanisms.

  19. Nuclear Plant Inspection

    Science.gov (United States)

    1983-01-01

    Engineers from the Power Authority of the State of New York use a Crack Growth Analysis Program supplied by COSMIC (Computer Software Management and Information Center) in one stage of nuclear plant inspection. Welds of the nuclear steam supply system are checked for cracks; radiographs, dye penetration and visual inspections are performed to locate cracks in the metal structure and welds. The software package includes three separate crack growth analysis models and enables necessary repairs to be planned before serious problems develop.

  20. 49 CFR 180.416 - Discharge system inspection and maintenance program for cargo tanks transporting liquefied...

    Science.gov (United States)

    2010-10-01

    ... couplings. (v) Loose or missing bolts or fastenings on bolted hose coupling assemblies. (2) No operator may... actuate. (iv) Rubber hose flexible connectors with any condition outlined in paragraph (g)(1) of this section. (v) Stainless steel flexible connectors with damaged reinforcement braid. (vi) Internal...

  1. Transporting "exceptional cargo" on the CERN sites

    CERN Multimedia

    EN Department

    2012-01-01

    When the Transport Service is managing "exceptional cargo", the driver and the escort are often in charge of an operation involving equipment worth many hundred thousand francs. Equipment that may well be irreplaceable for a facility or an experiment.   The members of the Transport Service who carry out these tasks are very professional and are – needless to say – highly concentrated on the job. They count on your understanding and support in the traffic on site. Their convoys are – for good reasons – moving slowly. Kindly do not overtake, do not cut in in front of them and do not drive too closely. Respect the escort and do not position yourself between the truck and the escort vehicles. The EN department counts on your courtesy on the road.  

  2. Rapid response calculation of LNG cargo containment system under sloshing load using wavelet transformation

    Science.gov (United States)

    Kim, Yooil

    2013-06-01

    Reliable strength assessment of the Liquefied Natural Gas (LNG) cargo containment system under the sloshing impact load is very difficult task due to the complexity of the physics involved in, both in terms of the hydrodynamics and structural mechanics. Out of all those complexities, the proper selection of the design sloshing load which is applied to the structural model of the LNG cargo containment system, is one of the most challenging one due to its inherent randomness as well as the statistical analysis which is tightly linked to the design sloshing load selection. In this study, the response based strength assessment procedure of LNG cargo containment system has been developed and proposed as an alternative design methodology. Sloshing pressure time history, measured from the model test, is decomposed into wavelet basis function targeting the minimization of the number of the basis function together with the maximization of the numerical efficiency. Then the response of the structure is obtained using the finite element method under each wavelet basis function of different scale. Finally, the response of the structure under entire sloshing impact time history is rapidly calculated by synthesizing the structural response under wavelet basis function. Through this analysis, more realistic response of the system under sloshing impact pressure can be obtained without missing the details of pressure time history such as rising pattern, oscillation due to air entrapment and decay pattern and so on. The strength assessment of the cargo containment system is then performed based on the statistical analysis of the stress peaks selected out of the obtained stress time history.

  3. Inspection Strategies for Concrete Bridges

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Thoft-Christensen, Palle

    1989-01-01

    In this paper an optimal inspection strategy for concrete bridges based on periodic routine and detailed inspections is presented. The failure mode considered is corrosion of the reinforcement due to chlorides. A simple modelling of the corrosion and of the inspection strategy is presented....... The optimal inspection strategy is determined from an optimization problem, where the design variables are time intervals between detailed inspections and the concrete cover. The strategy is illustrated on a simple structure, namely a reinforced concrete beam....

  4. Air Quality in Mexico City: Policies Implemented for its Improvement

    Science.gov (United States)

    Paramo, V.

    2007-12-01

    stringent emission levels of the gasoline fleet; update the detention of pollutant vehicles program; partial exemption of the inspection and maintenance program for cleaner and or highly efficient vehicles; substitution of 3,000 microbuses, 40,000 taxis and 1,200 buses; commissioning of the first Bus Rapid Transit system; implementation of a program for the emissions reduction for the 300 most polluted industrial facilities; and continuous update of the air quality environmental management programs. To continue improving the air quality in the MCMA, the environmental authorities will continue the implementation of the 2002-2010 Air Quality Improvement Program. In 2007 the Green Program was started, this includes those actions that have proven to be effective reduction of pollutant emissions and incorporates new actions for the reduction of local and global pollutant emissions. The most important of these new actions are: substitution of 9,500 microbuses; renewal of all the taxis fleet; commissioning of 10 Bus Rapid Transit lines; commissioning of Line 12 of the underground system; schedules and routes limitations to the cargo fleet; increase 5 percent the number of non-motorized trips (bicycling and walking); regulation of the private public transport passenger stops; requirement of private schools to provide school transport; regulation of non-occupied taxis in circulation; modifications to the circulation of 350 critical crossing points in the city; adoption of intelligent traffic lights systems; complete substitution of the local government vehicle's fleet; implement the inspection and maintenance of the cargo fleet; introduction of low- sulfur diesel, among other measures.

  5. Estimating Cargo Airdrop Collateral Damage Risk

    Science.gov (United States)

    2011-03-01

    Acronyms AGU: Airborne Guidance Unit AFI: Air Force Instruction AMC: Air Mobility Command API: Actual Point of Impact ARVN: The Army of the Republic...describe the two-dimensional distribution of current airdrop errors through research and analyzing recent operational airdrop score data. Air Mobility ...20System%20Advanced%20Concept%20T echnology %20Demonstration.pdf Berry, William G. and Leon W. Laugginger. A Computer Simulation of Release

  6. Neutron and Photon Transport in Sea-Going Cargo Containers

    Energy Technology Data Exchange (ETDEWEB)

    Pruet, J; Descalle, M; Hall, J; Pohl, B; Prussin, S G

    2005-02-09

    Factors affecting sensing of small quantities of fissionable material in large sea-going cargo containers by neutron interrogation and detection of {beta}-delayed photons are explored. The propagation of variable-energy neutrons in cargos, subsequent fission of hidden nuclear material and production of the {beta}-delayed photons, and the propagation of these photons to an external detector are considered explicitly. Detailed results of Monte Carlo simulations of these stages in representative cargos are presented. Analytical models are developed both as a basis for a quantitative understanding of the interrogation process and as a tool to allow ready extrapolation of the results to cases not specifically considered here.

  7. AIR CANADA:A REAL HOME IN THE SKY

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Air Canada, together with its regional airline subsidiary, Air Canada Jazz, provides scheduled and charter air transportation for passengers and cargo to more than 150 destinations,vacation packages to over 90 destinations, as well as maintenance, ground handling and train ing services to other airlines.

  8. A development of an automated ultrasonic TOFD inspection system using an welding line tracing robot

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Hyun; Song, Sung Jin [Sungkyunkwan Univeristy, Seoul (Korea, Republic of); Lee, Kang Won; Kim, Young Jin [Korea Institue of Inductrial Technology, Daejeon (Korea, Republic of); Woo, Jong Sik [Seascan Inc. Ltd., Daejeon (Korea, Republic of)

    2006-05-15

    Large scaled ships, manufactured inside of the country, should be passed welding inspection and painting film inspection. Normally, these kind of inspections are conducted by human inspectors manually, although it cause industrial disasters such as falling accidents and diving accidents frequently. In addition, Ship makers are not to give a full trust to shipowners because manual inspections cannot be conducted all over the welding parts. So, in this study we developed an automated ultrasonic TOFD inspection system using an welding line tracing robot. This system, controlled by an inspector at a remote field, can inspect welding parts of ship outer panel both under water and in air. In this paper we present the developed robot and ultrasonic TOFD inspection system and the inspection result.

  9. A development of an automated ultrasonic TOFD inspection system using an welding line tracing robot

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Hyun; Song, Sung Jin [Sungkyunkwan Univeristy, Seoul (Korea, Republic of); Lee, Kang Won; Kim, Young Jin [Korea Institue of Inductrial Technology, Daejeon (Korea, Republic of); Woo, Jong Sik [Seascan Inc. Ltd., Daejeon (Korea, Republic of)

    2006-05-15

    Large scaled ships, manufactured inside of the country, should be passed welding inspection and painting film inspection. Normally, these kind of inspections are conducted by human inspectors manually, although it cause industrial disasters such as falling accidents and diving accidents frequently. In addition, Ship makers are not to give a full trust to ship owners because manual inspections cannot be conducted all over the welding parts. So, in this study we developed an automated ultrasonic TOFD inspection system using an welding line tracing robot. This system, controlled by an inspector at a remote field, can inspect welding parts of ship outer panel both under water and in air. In this paper we present the developed robot and ultrasonic TOFD inspection system and the inspection result.

  10. Advances in inspection automation

    Science.gov (United States)

    Weber, Walter H.; Mair, H. Douglas; Jansen, Dion; Lombardi, Luciano

    2013-01-01

    This new session at QNDE reflects the growing interest in inspection automation. Our paper describes a newly developed platform that makes the complex NDE automation possible without the need for software programmers. Inspection tasks that are tedious, error-prone or impossible for humans to perform can now be automated using a form of drag and drop visual scripting. Our work attempts to rectify the problem that NDE is not keeping pace with the rest of factory automation. Outside of NDE, robots routinely and autonomously machine parts, assemble components, weld structures and report progress to corporate databases. By contrast, components arriving in the NDT department typically require manual part handling, calibrations and analysis. The automation examples in this paper cover the development of robotic thickness gauging and the use of adaptive contour following on the NRU reactor inspection at Chalk River.

  11. 49 CFR 178.320 - General requirements applicable to all DOT specification cargo tank motor vehicles.

    Science.gov (United States)

    2010-10-01

    ...) Each cargo tank or cargo tank motor vehicle design type, including its required accident damage... specification cargo tank motor vehicles. 178.320 Section 178.320 Transportation Other Regulations Relating to... Transportation § 178.320 General requirements applicable to all DOT specification cargo tank motor vehicles....

  12. 46 CFR 153.436 - Heat transfer fluids: compatibility with cargo.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Heat transfer fluids: compatibility with cargo. 153.436... Equipment Cargo Temperature Control Systems § 153.436 Heat transfer fluids: compatibility with cargo. A heat transfer fluid separated from the cargo by only one wall (for example, the heat transfer fluid in a...

  13. Container inspection in the port container terminal by using 14 MeV neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Valkovic, Vladivoj [Institute Ruder Boskovic, Zagreb (Croatia); Kvinticka 62, Zagreb (Croatia); Sudac, Davorin; Nad, Karlo; Obhodas, Jasmina [Ruder Boskovic Institute, Bijenicka c.54, Zagreb (Croatia)

    2015-07-01

    A proposal for an autonomous and flexible ship container inspection system is presented. This could be accomplished by the incorporation of inspection system on the container transportation devices (straddle carriers, yard gentry cranes automated guided vehicles, trailers). This configuration is terminal specific and it will be decided by container terminal operator. In such a way no part of port operational area will be used for inspection. The inspection scenario will include container transfer from ship to transportation device with inspection unit mounted on it, inspection during container movement to the container location. A neutron generator without associated alpha particle detection will be used. This will allow the use of higher neutron intensity (5x10{sup 9} - 10{sup 10} n/s in 4π). The inspected container will be stationary in the 'inspection position' on the transportation device while the 'inspection unit' will move along its side. Following analytical methods will be used simultaneously: neutron radiography, X-ray radiography, neutron activation analysis, (n,γ) and (n,n'γ) reactions, neutron absorption, and scattering, X-ray backscattering, Neutron techniques will take the advantage of using 'smart collimators' for neutrons and gammas, both emitted and detected. The inspected voxel will be defined by intersections/union of neutron generator and detectors solid angles. The container inspection protocol will be based on identification of discrepancies between its cargo manifest and its elemental 'fingerprint' and radiography profiles. In addition, the information on container weight will be obtained during the container transport and foreseen screening from the measurement of density of material in the container. (authors)

  14. Inspection management system

    Energy Technology Data Exchange (ETDEWEB)

    Coto, L.F.M.; Alvarez, M.A.L.

    1998-07-01

    The main features of the application developed by UNION FENOSA and NorControl for inspection management are exposed. This application has been built on the basis of a Geographic Information System, whose advantages on other database systems are explained. This system, has been developed with the main objective of getting a better and easier utilization of the data collected from the inspections, in order to reduce service failures and obtain a bigger return of the effort invested in them. They are also exposed the work line and the steps followed for the implementation of the system in the Meirama steam plant, and the results obtained up to date.

  15. Computer vision barrel inspection

    Science.gov (United States)

    Wolfe, William J.; Gunderson, James; Walworth, Matthew E.

    1994-02-01

    One of the Department of Energy's (DOE) ongoing tasks is the storage and inspection of a large number of waste barrels containing a variety of hazardous substances. Martin Marietta is currently contracted to develop a robotic system -- the Intelligent Mobile Sensor System (IMSS) -- for the automatic monitoring and inspection of these barrels. The IMSS is a mobile robot with multiple sensors: video cameras, illuminators, laser ranging and barcode reader. We assisted Martin Marietta in this task, specifically in the development of image processing algorithms that recognize and classify the barrel labels. Our subsystem uses video images to detect and locate the barcode, so that the barcode reader can be pointed at the barcode.

  16. Bidirectionality From Cargo Thermal Fluctuations in Motor-Mediated Transport

    CERN Document Server

    Miles, Christopher E

    2016-01-01

    Molecular motor proteins serve as an essential component of intracellular transport by generating forces to haul cargoes along cytoskeletal filaments. In some circumstances, two species of motors that are directed oppositely (e.g. kinesin, dynein) can be attached to the same cargo. The resulting net motion is known to be bidirectional, but the mechanism of switching remains unclear. In this work, we propose a mean-field mathematical model of the mechanical interactions of two populations of molecular motors with diffusion of the cargo (thermal fluctuations) as the fundamental noise source. By studying a simplified model, the delayed response of motors to rapid fluctuations in the cargo is quantified, allowing for the reduction of the full model to two "characteristic positions" of each of the motor populations. The system is then found to be "metastable", switching between two distinct directional transport states, or bidirectional motion. The time to switch between these states is then investigated using WKB...

  17. Stochastic modeling of cargo transport by teams of molecular motors

    CERN Document Server

    Klein, Sarah; Santen, Ludger

    2014-01-01

    Many different types of cellular cargos are transported bidirectionally along microtubules by teams of molecular motors. The motion of this cargo-motors system has been experimentally characterized in vivo as processive with rather persistent directionality. Different theoretical approaches have been suggested in order to explore the origin of this kind of motion. An effective theoretical approach, introduced by M\\"uller et al., describes the cargo dynamics as a tug-of-war between different kinds of motors. An alternative approach has been suggested recently by Kunwar et al., who considered the coupling between motor and cargo in more detail. Based on this framework we introduce a model considering single motor positions which we propagate in continuous time. Furthermore, we analyze the possible influence of the discrete time update schemes used in previous publications on the system's dynamic.

  18. Cargo Loading Facilities, Published in unknown, Arizona Department of Transportation.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cargo Loading Facilities dataset as of unknown. Data by this publisher are often provided in State Plane coordinate system; in a Transverse Mercator projection;...

  19. Cargo/Weapons Elevator Land Based Engineering Site

    Data.gov (United States)

    Federal Laboratory Consortium — The Cargo and Weapons Facility consists of a suite of full scale and component test facilities contiguously located in building 77H. The site was constructed in 1987...

  20. Reducing Aerodynamic Drag on Empty Open Cargo Vehicles

    Science.gov (United States)

    Ross, James C.; Storms, Bruce L.; Dzoan, Dan

    2009-01-01

    Some simple structural modifications have been demonstrated to be effective in reducing aerodynamic drag on vehicles that have empty open cargo bays. The basic idea is to break up the airflow in a large open cargo bay by inserting panels to divide the bay into a series of smaller bays. In the case of a coal car, this involves inserting a small number (typically between two and four) of vertical full-depth or partial-depth panels.

  1. SIMULATIONS FOR ACTIVE INTERROGATION OF HEU IN CARGO CONTAINERS

    Energy Technology Data Exchange (ETDEWEB)

    LEE, SANG Y. [Los Alamos National Laboratory; BEDDINGFIELD, DAVID H. [Los Alamos National Laboratory; PARK, JAEYOUNG [Los Alamos National Laboratory

    2007-01-22

    We describe the results of a Monte Carlo simulation 10 investigate the feasibility of using a pulsed deuterium-tritium (D-T) neutron technique for active interrogation of special nuclear material in cargo containers. Time distributions of fission neutrons from highly enriched uranium induced by a pulsed D-T neutron source were calculated for cargo containers with different hydrogen contents. A simple detector system with polyethylene and cadmium was modeled to calculate the two-group neutron flux at the detector.

  2. Modern approaches to cargo protection of rail transportation

    Directory of Open Access Journals (Sweden)

    Денис Викторович Ломотько

    2014-12-01

    Full Text Available On the basis of the study we have proposed a number of measures to improve the cargo protection during rail transportation. The economic impact of some of them is estimated. The legal relations of railways and cargo owners in terms of liability for failure to preserve are considered and proposed the management model of insurance risks of failure to preserve in transportation.

  3. Vibration and acoustic environments for payload/cargo integration

    Science.gov (United States)

    Hill, R. E.; Coody, M. C.

    1983-01-01

    Shuttle orbiter launch vibration and acoustic environments for cargo bay/payload interfaces are predicted. Data acquired during Shuttle flight tests are compared with the preflight estimates. Vibration response data for payload attachment locations are presented, along with acoustic data in the form of noise-level spectra measured at various locations in the cargo bay and space averages of the noise levels. It is shown that the payload-bay vibration and acoustic environments are generally less severe than predicted.

  4. INSPECTION TECHNOLOGY, DETECTION, AND COMPLIANCE: EVIDENCE FROM FLORIDA RESTAURANT INSPECTIONS

    OpenAIRE

    Jin, Ginger Zhe; Lee, Jungmin

    2014-01-01

    In this article, we show that a small innovation in inspection technology can make substantial differences in inspection outcomes. For restaurant hygiene inspections, the state of Florida has introduced a handheld electronic device, the portable digital assistant (PDA), which reminds inspectors of 1,000 potential violations that may be checked for. Using inspection records from July 2003 to June 2009, we find that the adoption of PDA led to 11% more detected violations and subsequently restau...

  5. Phototriggered cargo release from virus-like assemblies.

    Science.gov (United States)

    Brasch, Melanie; Voets, Ilja K; Koay, Melissa S T; Cornelissen, Jeroen J L M

    2013-01-01

    There has been tremendous progress towards the development of responsive polymers that are programmed to respond to an external stimulus such as light, pH and temperature. The unique combination of molecular packaging followed by slow, controlled release of molecular cargo is of particular importance for self-healing materials and the controlled release of drugs. While much focus and progress remains centred around synthetic carriers, viruses and virus-like particles can be considered ideal cargo carriers as they are intrinsically designed to package, protect and deliver nucleic acid cargo to host cells. Here, we report the encapsulation of a stimuli-responsive self-immolative polymer within virus-like assemblies of Cowpea Chlorotic Mottle Virus. Upon photo-irradiation, the self-immolative polymer undergoes a head-to-tail depolymerization into its monomeric subunits, resulting in the slow release of the molecular cargo. We propose that the liberated monomers are small enough to diffuse through the pores of the virus capsid shell and offer an alternative strategy for the controlled loading and unloading of the molecular cargo using viruses as cargo carriers.

  6. Ofsted Re-Inspected

    Science.gov (United States)

    Coffield, Frank

    2012-01-01

    The author never thought he would have to thank Ofsted for a change in its approach that may result in a major improvement in provision; and yet, with the introduction of the revised Common Inspection Framework (CIF), it has made teaching and learning (T&L) the first priority throughout the learning and skills sector. While he wishes to…

  7. SpaceX Dragon Air Circulation System

    Science.gov (United States)

    Hernandez, Brenda; Piatrovich, Siarhei; Prina, Mauro

    2011-01-01

    The Dragon capsule is a reusable vehicle being developed by Space Exploration Technologies (SpaceX) that will provide commercial cargo transportation to the International Space Station (ISS). Dragon is designed to be a habitable module while it is berthed to ISS. As such, the Dragon Environmental Control System (ECS) consists of pressure control and pressure equalization, air sampling, fire detection, illumination, and an air circulation system. The air circulation system prevents pockets of stagnant air in Dragon that can be hazardous to the ISS crew. In addition, through the inter-module duct, the air circulation system provides fresh air from ISS into Dragon. To utilize the maximum volume of Dragon for cargo packaging, the Dragon ECS air circulation system is designed around cargo rack optimization. At the same time, the air circulation system is designed to meet the National Aeronautics Space Administration (NASA) inter-module and intra-module ventilation requirements and acoustic requirements. A flight like configuration of the Dragon capsule including the air circulation system was recently assembled for testing to assess the design for inter-module and intra-module ventilation and acoustics. The testing included the Dragon capsule, and flight configuration in the pressure section with cargo racks, lockers, all of the air circulation components, and acoustic treatment. The air circulation test was also used to verify the Computational Fluid Dynamics (CFD) model of the Dragon capsule. The CFD model included the same Dragon internal geometry that was assembled for the test. This paper will describe the Dragon air circulation system design which has been verified by testing the system and with CFD analysis.

  8. Failure of cargo aileron’s actuator

    Directory of Open Access Journals (Sweden)

    G. Zucca

    2014-10-01

    Full Text Available During a ferry flight, in a standard operation condition and at cruising level, a military cargo experienced a double hydraulic system failure due to a structural damage of the dual booster actuator. The booster actuator is the main component in mechanism of aileron’s deflection. The crew was able to arrange an emergency landing thanks to the spare oil onboard: load specialists refilled the hydraulic reservoirs. Due to safety concerns and in order to prevent the possibility of other similar incidents, a technical investigation took place. The study aimed to carry out the analysis of root causes of the actuator failure. The Booster actuator is composed mainly by the piston rod and its aluminum external case (AA7049. The assembly has two bronze caps on both ends. These are fixed in position by means of two retainers. At one end of the actuator case is placed a trunnion: a cylindrical protrusion used as a pivoting point on the aircraft. The fracture was located at one end of the case, on the trunnion side, in correspondence to the cap and over the retainer. One of the two fracture surfaces was found separated to the case and with the cap entangled inside. The fracture surfaces of the external case indicated fatigue crack growth followed by ductile separation. The failure analysis was performed by means of optical, metallographic, digital and electronic microscopy. The collected evidences showed a multiple initiation fracture mechanism. Moreover, 3D scanner reconstruction and numerical simulation demonstrated that dimensional non conformances and thermal loads caused an abnormal stress concentration. Stress concentration was located along the case assy outer surface where the fatigue crack originated. The progressive rupture mechanism grew under cyclical axial load due to the normal operations. Recommendations were issued in order to improve dimensional controls and assembly procedures during production and overhaul activities.

  9. Overview of the software inspection process

    Energy Technology Data Exchange (ETDEWEB)

    Lane, G.L.; Dabbs, R. [Sandia National Labs., Albuquerque, NM (United States)

    1997-11-01

    This tutorial introduces attendees to the Inspection Process and teaches them how to organize and participate in a software inspection. The tutorial advocates the benefits of inspections and encourages attendees to socialize the inspection process in their organizations.

  10. 7 CFR 29.40 - Mandatory inspection.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.40 Mandatory inspection. Inspection authorized or required under section 5 of the Act or Section 759 of the Appropriations Act. definitions...

  11. Spectroscopic neutron radiography for a cargo scanning system

    Science.gov (United States)

    Rahon, Jill; Danagoulian, Areg; MacDonald, Thomas D.; Hartwig, Zachary S.; Lanza, Richard C.

    2016-06-01

    Detection of cross-border smuggling of illicit materials and contraband is a challenge that requires rapid, low-dose, and efficient radiographic technology. The work we describe here is derived from a technique which uses monoenergetic gamma rays from low energy nuclear reactions, such as 11B(d,nγ)12C, to perform radiographic analysis of shipping containers. Transmission ratios of multiple monoenergetic gamma lines resulting from several gamma producing nuclear reactions can be employed to detect materials of high atomic number (Z), the details of which will be described in a separate paper. Inherent in this particular nuclear reaction is the production of fast neutrons which could enable neutron radiography and further characterization of the effective-Z of the cargo, especially within the range of lower Z. Previous research efforts focused on the use of total neutron counts in combination with X-ray radiography to characterize the hydrogenous content of the cargo. We present a technique of performing transmitted neutron spectral analysis to reconstruct the effective Z and potentially the density of the cargo. This is made possible by the large differences in the energy dependence of neutron scattering cross-sections between hydrogenous materials and those of higher Z. These dependencies result in harder transmission spectra for hydrogenous cargoes than those of non-hydrogenous cargoes. Such observed differences can then be used to classify the cargo based on its hydrogenous content. The studies presented in this paper demonstrate that such techniques are feasible and can provide a contribution to cargo security, especially when used in concert with gamma radiography.

  12. Cargo binding activates myosin VIIA motor function in cells.

    Science.gov (United States)

    Sakai, Tsuyoshi; Umeki, Nobuhisa; Ikebe, Reiko; Ikebe, Mitsuo

    2011-04-26

    Myosin VIIA, thought to be involved in human auditory function, is a gene responsible for human Usher syndrome type 1B, which causes hearing and visual loss. Recent studies have suggested that it can move processively if it forms a dimer. Nevertheless, it exists as a monomer in vitro, unlike the well-known two-headed processive myosin Va. Here we studied the molecular mechanism, which is currently unknown, of activating myosin VIIA as a cargo-transporting motor. Human myosin VIIA was present throughout cytosol, but it moved to the tip of filopodia upon the formation of dimer induced by dimer-inducing reagent. The forced dimer of myosin VIIA translocated its cargo molecule, MyRip, to the tip of filopodia, whereas myosin VIIA without the forced dimer-forming module does not translocate to the filopodial tips. These results suggest that dimer formation of myosin VIIA is important for its cargo-transporting activity. On the other hand, myosin VIIA without the forced dimerization module became translocated to the filopodial tips in the presence of cargo complex, i.e., MyRip/Rab27a, and transported its cargo complex to the tip. Coexpression of MyRip promoted the association of myosin VIIA to vesicles and the dimer formation. These results suggest that association of myosin VIIA monomers with membrane via the MyRip/Rab27a complex facilitates the cargo-transporting activity of myosin VIIA, which is achieved by cluster formation on the membrane, where it possibly forms a dimer. Present findings support that MyRip, a cargo molecule, functions as an activator of myosin VIIA transporter function.

  13. Spectroscopic neutron radiography for a cargo scanning system

    Energy Technology Data Exchange (ETDEWEB)

    Rahon, Jill [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States); Danagoulian, Areg, E-mail: aregjan@mit.edu [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States); MacDonald, Thomas D. [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States); Hartwig, Zachary S. [Plasma Science and Fusion Center, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States); Lanza, Richard C. [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139 (United States)

    2016-06-01

    Detection of cross-border smuggling of illicit materials and contraband is a challenge that requires rapid, low-dose, and efficient radiographic technology. The work we describe here is derived from a technique which uses monoenergetic gamma rays from low energy nuclear reactions, such as {sup 11}B(d,nγ){sup 12}C, to perform radiographic analysis of shipping containers. Transmission ratios of multiple monoenergetic gamma lines resulting from several gamma producing nuclear reactions can be employed to detect materials of high atomic number (Z), the details of which will be described in a separate paper. Inherent in this particular nuclear reaction is the production of fast neutrons which could enable neutron radiography and further characterization of the effective-Z of the cargo, especially within the range of lower Z. Previous research efforts focused on the use of total neutron counts in combination with X-ray radiography to characterize the hydrogenous content of the cargo. We present a technique of performing transmitted neutron spectral analysis to reconstruct the effective Z and potentially the density of the cargo. This is made possible by the large differences in the energy dependence of neutron scattering cross-sections between hydrogenous materials and those of higher Z. These dependencies result in harder transmission spectra for hydrogenous cargoes than those of non-hydrogenous cargoes. Such observed differences can then be used to classify the cargo based on its hydrogenous content. The studies presented in this paper demonstrate that such techniques are feasible and can provide a contribution to cargo security, especially when used in concert with gamma radiography.

  14. Inspection and teachers’ emotions: An emotional evaluation of inspection

    Directory of Open Access Journals (Sweden)

    Binali Tunç

    2015-02-01

    Full Text Available In the study, inspection is discussed in relation to the teachers’ feelings and emotions it creates before inspection, during inspection and after inspection process. Teacher’s emotions have been investigated intentionally as emotional side of education has been neglected. Education is closely related to the emotions of teachers, who are the most important producers of educational activities.Educational activities are reduced to standard activities and defined with simple explanations or single labels such as ‘good-bad’, ‘successful-unsuccessful’, ‘adequate-inadequate’. Inspection causes emotions to be neglected. Moreover, recently, it has been discussed that there are approaches and systems that suggest constant and multi-dimensional inspection instead of traditional inspection.Qualitative research model was used to understand of teacher emotions. A semi structured form was used for the 38 primary school teachers’ interviews. After teacher interviews were completed, we analyzed and compared the interviews. Participants’ expressions were checked in terms of correctness, potential validity and reliability problems such as misinterpretation.   The results of the study can be summarized as follows: There were no positive expressions related to the emotional impact of inspection on teachers. In addition, teachers felt that the inspectors were stressed, anxious, uneasy, accusatory, coercive, looking for defect and areas of unsuccessful teaching performance. Most of teachers reported that being observed and evaluated caused them to have negative emotions.Teachers’ perceptions about inspection are found to be negative. There are no statements that indicate there is a positive impression of inspection on teachers. The emotions that are experienced before inspection: pressure, hurry, stress, concern, tension, anxiety, worry, uncertainty; during inspection: stress, tension, anger, loss of strength, humiliation and lack of self

  15. Project CarGO tram at Dresden; Projekt CarGo Tram in Dresden

    Energy Technology Data Exchange (ETDEWEB)

    Mueller-Eberstein, F.; Franke, M. [Dresdner Verkehrsbetriebe AG, Dresden (Germany)

    2000-05-01

    Next year, the Glassen Volkswagen Factory, which is currently under construction, will commence the production of luxury class automobiles. Already buying a car is meant to be a special event; thus the factory is set in a baroque environment, near the famous Semper Opera and Picture Gallery. This arrangement, hitherto without example, will be accompanied by another, equally remarkable project. The factory, which is situated in a central city area being very sensitive in terms of urban development and traffic installations, will be delivered raw materials and parts using a CarGo Tram. Two bi-directionally operated, 60 metres long five-car trains will transport the parts from the railway cargo hub at Dresden Friedrichstadt to the factory in cycles of 40 minutes. There and at the Glassen Factory in Grosser Garten, separate track terminals will be built. In addition to the historic past and the charming scenery of the Elbe metropolis Dresden and its environs, soon also the CarGo Tram and the Glassen Factory will attract guests from all over the world to visit this innovative and culturally important city in the centre of Europe. (orig.) [German] Im Jahr 2001 beginnt die Produktion von Automobilen der Oberklasse in der derzeit noch im Bau befindlichen Glaesernen Manufaktur der Volkswagen Automobil-Manufaktur Dresden GmbH. In einem barocken Umfeld, mit raeumlicher Naehe zur Semperoper und Gemaeldegalerie, soll bereits der Verkauf dieser Fahrzeuge zu einem Erlebnis werden. Dieses bisher einmalige Vorhaben wird von einem zweiten, ebenso einzigartigen Vorhaben begleitet. Die Belieferung der in einem staedtebaulich und verkehrlich sensiblen Innenstadtbereich gelegenen Manufaktur erfolgt mit einer Gueterstrassenbahn. Zwei 60 Meter lange, fuenfteilige Zweirichtungsfahrzeuge werden ab Maerz 2001 etwa im 40-Minutentakt die Anlieferung der Zulieferteile aus dem Gueterverkehrszentrum Dresden-Friedrichstadt uebernehmen. Hier und an der Glaesernen Manufaktur im Grossen Garten werden

  16. Cooperative behavior of molecular motors: Cargo transport and traffic phenomena

    Science.gov (United States)

    Lipowsky, Reinhard; Beeg, Janina; Dimova, Rumiana; Klumpp, Stefan; Müller, Melanie J. I.

    2010-01-01

    All eukaryotic cells including those of our own body contain complex transport systems based on molecular motors which walk along cytoskeletal filaments. These motors are rather small and make discrete mechanical steps with a step size of the order of 10 nm but are able to pull cargo particles over much larger distances, from micrometers up to meters. In vivo, the intracellular cargos include large membrane-bounded organelles, smaller vesicles, a subset of mRNAs, cytoskeletal filaments, and various protein building blocks, which are transported between different cell compartments. This cargo transport is usually performed by teams of motors. If all motors belong to the same molecular species, the cooperative action of the motors leads to uni-directional transport with a strongly increased run length and with a characteristic force dependence of the velocity distributions. If two antagonistic teams of motors pull on the same cargo particle, they perform a stochastic tug-of-war, which is characterized by a subtle force balance between the two motor teams and leads to several distinct patterns of bi-directional transport. So far, all experimental observations on bi-directional transport are consistent with such a tug-of-war. If many motors and/or cargo particles are transported along the filaments, one encounters various traffic phenomena. Depending on their mutual interactions and the compartment geometry, the motors form various spatio-temporal patterns such as traffic jams, and undergo nonequilibrium phase transitions between different patterns of transport.

  17. Stokes Efficiency of Molecular Motor-Cargo Systems

    Directory of Open Access Journals (Sweden)

    Hongyun Wang

    2008-01-01

    Full Text Available A molecular motor utilizes chemical free energy to generate a unidirectional motion through the viscous fluid. In many experimental settings and biological settings, a molecular motor is elastically linked to a cargo. The stochastic motion of a molecular motor-cargo system is governed by a set of Langevin equations, each corresponding to an individual chemical occupancy state. The change of chemical occupancy state is modeled by a continuous time discrete space Markov process. The probability density of a motor-cargo system is governed by a two-dimensional Fokker-Planck equation. The operation of a molecular motor is dominated by high viscous friction and large thermal fluctuations from surrounding fluid. The instantaneous velocity of a molecular motor is highly stochastic: the past velocity is quickly damped by the viscous friction and the new velocity is quickly excited by bombardments of surrounding fluid molecules. Thus, the theory for macroscopic motors should not be applied directly to molecular motors without close examination. In particular, a molecular motor behaves differently working against a viscous drag than working against a conservative force. The Stokes efficiency was introduced to measure how efficiently a motor uses chemical free energy to drive against viscous drag. For a motor without cargo, it was proved that the Stokes efficiency is bounded by 100% [H. Wang and G. Oster, (2002]. Here, we present a proof for the general motor-cargo system.

  18. Anomalous motor mediated cargo transport in microtubule networks

    Science.gov (United States)

    Vandal, Steven; Macveigh-Fierro, Daniel; Shen, Zhiyuan; Lemoi, Kyle; Vidali, Luis; Ross, Jennifer; Tuzel, Erkan

    Cargo transport is an important biological mechanism by which cells locomote, self-organize, and actively transport organelles. This transport is mediated by the cytoskeletal network and molecular motors; however, it is not known how network self-organization and dynamics affect these transport processes. In order to develop a mechanistic understanding of cargo transport, we use a coarse-grained Brownian dynamics model that incorporates the dynamics of these networks, as well as experimentally determined motor properties. We will test these models with two experimental systems: (1) in vitro microtubule networks with kinesin-1 motors, and quantum dot cargos on recreated microtubule networks, and (2) an excellent model organism, the moss Physcomitrella patens, in which chloroplasts are transported via the microtubule network by means of kinesin-like proteins. Phenomenological network characterizations are made, both in vivo and in vitro, and cargo motility is characterized using Mean Squared Displacement (MSD) measurements. Our simulations shed light on the role of network density and motor properties on the observed transport behavior, and improve our understanding of cargo transport in cells.

  19. Design and accomplishment for the monitoring unit of the sup 6 sup 0 Co train freight inspection system

    CERN Document Server

    Cong Peng

    2002-01-01

    The sup 6 sup 0 Co railway cargo inspection system has super automaticity. And the monitoring unit is an important part of the automatic control system. The author introduces the idea of designing the monitoring unit in detail and accomplishes a new-style unit which is different from the traditional one. The monitoring unit which is highly integrated, easy to be mounted and debugged and convenient to be operated and maintained has play an excellent role in the work of the whole inspection system

  20. A Heuristic Approach to Determining Cargo Flow and Scheduling for Air Mobility Command’s Channel Cargo System

    Science.gov (United States)

    1994-03-01

    Hillier, and Floyd ( Bazaraa et al., 1990:625). Chapter IV discusses the selection of the specific S-P algorithm in more detail. 12 11.4.2 Schedule...July 8-12, 1991. Bazaraa , Mokhtar S., John J. Jarvis and Hanif D. Sherali. Linear Programming and Network Flows. New York: John Wiley & Sons, 1990

  1. An Active Endoscopy Robotic System for Direct Tracheal Inspection

    Institute of Scientific and Technical Information of China (English)

    YU Lian-zhi; YAN Guo-zheng; MA Guan-ying; ZAN Peng

    2007-01-01

    The development of active endoscopy techniques is one important area of medical robot. This paper designed a new flexible and active endoscopy robotic system for direct tracheal inspection. The mobile mechanism of the robot is based on the inchworm movement actuated by pneumatic rubber actuator. There are five air chambers controlled independently, by adjusting pressures in air chambers, the robot can move in a straight mode or in a bending mode. The inspection sensors and some therapy surgery tools can be equipped in the front of the robot.The prototype was made and its mechanical characteristics were analyzed. The robot could move smoothly in a small plastic tube, and the robot is respectable to be used for inspection in human trachea directly.

  2. Reducing Mission Logistics with Multipurpose Cargo Transfer Bags

    Science.gov (United States)

    Baccus, Shelley; Broyan, James Lee, Jr.; Borrego, Melissa

    2016-01-01

    The Logistics Reduction (LR) project within Advanced Exploration Systems (AES) is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) have been designed such that they can serve the same purpose as a Cargo Transfer Bag (CTB), the common logistics carrying bag for the International Space Station (ISS). After use as a cargo carrier, a regular CTB becomes trash, whereas the MCTB can be unfolded into a flat panel for reuse. Concepts and potential benefits for various MCTB applications will be discussed including partitions, crew quarters, solar radiation storm shelters, acoustic blankets, and forward osmosis water processing. Acoustic MCTBs are currently in use on ISS to reduce the noise generated by the T2 treadmill, which reaches the hazard limit at high speeds. The development of the AMCTB included identification of keep-out zones, acoustic properties, deployment considerations, and structural testing. Features developed for these considerations are applicable to MCTBs for all crew outfitting applications.

  3. Multipurpose Cargo Transfer Bags fro Reducing Exploration Mission Logistics

    Science.gov (United States)

    Baccus, Shelley; Broyan, James Lee, Jr.; Borrego, Melissa

    2016-01-01

    The Logistics Reduction (LR) project within the Advanced Exploration Systems (AES) division is tasked with reducing logistical mass and repurposing logistical items. Multipurpose Cargo Transfer Bags (MCTB) have been designed such that they can serve the same purpose as a Cargo Transfer Bag (CTB), the common logistics carrying bag for the International Space Station (ISS). After use as a cargo carrier, a regular CTB becomes trash, whereas the MCTB can be unfolded into a flat panel for reuse. Concepts and potential benefits for various MCTB applications will be discussed including partitions, crew quarters, solar radiation storm shelters, acoustic blankets, and forward osmosis water processing. Acoustic MCTBs are currently in use on ISS to reduce the noise generated by the T2 treadmill, which reaches the hazard limit at high speeds. The development of the AMCTB included identification of keep out zones, acoustic properties, deployment considerations, and structural testing. Features developed for these considerations are applicable to MCTBs for all crew outfitting applications.

  4. Coupling of Active Motion and Advection Shapes Intracellular Cargo Transport

    CERN Document Server

    Trong, P Khuc; Goldstein, R E; 10.1103/PhysRevLett.109.028104

    2012-01-01

    Intracellular cargo transport can arise from passive diffusion, active motor-driven transport along cytoskeletal filament networks, and passive advection by fluid flows entrained by such motor/cargo motion. Active and advective transport are thus intrinsically coupled as related, yet different representations of the same underlying network structure. A reaction-advection-diffusion system is used here to show that this coupling affects the transport and localization of a passive tracer in a confined geometry. For sufficiently low diffusion, cargo localization to a target zone is optimized either by low reaction kinetics and decoupling of bound and unbound states, or by a mostly disordered cytoskeletal network with only weak directional bias. These generic results may help to rationalize subtle features of cytoskeletal networks, for example as observed for microtubules in fly oocytes.

  5. Optimizing an undulating magnetic microswimmer for cargo towing

    Science.gov (United States)

    Gutman, Emiliya; Or, Yizhar

    2016-06-01

    One of the promising capabilities of magnetic microswimmers is towing a cargo, which can be used for targeted drug delivery or performing tissue biopsy. A key question is what should be the optimal size ratio between the cargo and the swimmer's flexible tail. This question is addressed here for the simplest theoretical model of a magnetic microswimmer undergoing planar undulations—a spherical load connected by a torsion spring to a rigid slender link. The swimmer's dynamic is formulated and leading-order expressions for its motion are obtained explicitly under small-amplitude approximation. Optimal combinations of magnetic actuation frequency, torsion stiffness, and tail length for maximizing displacement, average speed, or energetic efficiency are obtained. The theoretical results are compared with reported experiments in several types of cargo-towing magnetic microswimmers.

  6. Shell Inspection History and Current CMM Inspection Efforts

    Energy Technology Data Exchange (ETDEWEB)

    Montano, Joshua Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-01-26

    The following report provides a review of past and current CMM Shell Inspection efforts. Calibration of the Sheffield rotary contour gauge has expired and the primary inspector, Matthew Naranjo, has retired. Efforts within the Inspection team are transitioning from maintaining and training new inspectors on Sheffield to off-the-shelf CMM technology. Although inspection of a shell has many requirements, the scope of the data presented in this report focuses on the inner contour, outer contour, radial wall thickness and mass comparisons.

  7. 14 CFR 91.415 - Changes to aircraft inspection programs.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Changes to aircraft inspection programs. 91.415 Section 91.415 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES...

  8. 14 CFR 91.413 - ATC transponder tests and inspections.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false ATC transponder tests and inspections. 91.413 Section 91.413 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES...

  9. Comparative study of Palito inspection and MFL Inspection

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Anne A. de; Miranda, Ivan Vicente Janvrot; Silva, Jose Augusto Pereira da [Pipeway Engenharia, Rio de Janeiro, RJ (Brazil); Guimaraes, Frederico S.; Magalhaes, Joao Alfredo P. [Minds at Work, Rio de Janeiro, RJ (Brazil); Sabino, Joao Marcos [Petroleo Brasileiro S.A. (PETROBRAS/UN-RN/CE), Natal, RN (Brazil). Unidade de Negocios Rio Grande do Norte e Ceara

    2009-07-01

    A 16 inches oil pipeline was surveyed with MFL and Palito pig in 2007. The MFL inspection was performed by Pipeway Engenharia while Palito inspection was performed by PETROBRAS. A comparison between the results of these two ILI inspections has been made to validate Palito Pig and to assess main characteristics and differences between the two techniques. The purpose of this paper is to detail the methodology applied to perform the comparison and to present a comparative study of results registered in the MFL and Palito inspections by Pipeway Engenharia, PETROBRAS/CENPES and CPTI/PUC-Rio. (author)

  10. Solving the Liner Shipping Fleet Repositioning Problem with Cargo Flows

    DEFF Research Database (Denmark)

    Tierney, Kevin; Askelsdottir, Björg; Jensen, Rune Møller;

    2015-01-01

    to reposition vessels as cheaply as possible without disrupting cargo flows. The LSFRP is characterized by chains of interacting activities with a multicommodity flow over paths defined by the activities chosen. Despite its industrial importance, the LSFRP has received little attention in the literature. We...... introduce a novel mathematical model and a simulated annealing algorithm for the LSFRP with cargo flows that makes use of a carefully constructed graph; we evaluate these approaches using real-world data from our industrial collaborator. Additionally, we compare the performance of our approach against...

  11. A matheuristic for the Cargo Mix Problem with Block Stowage

    DEFF Research Database (Denmark)

    Christensen, Jonas Mark; Pacino, Dario

    2017-01-01

    The cargo-mix problem aims at selecting the amount of containers of a given type to load on a vessel. In this article we present an extended definition that includes the analysis of a circular route with draft restrictions, limitations on expected cargo and the use of a block stowage strategy. A ....... A compact formulation of the problem based on the state-of-the-art heuristic decomposition is shown not to be able to solve the extended problem, thus a matheuristic approach is presented that can achieve high quality results in a matter of seconds....

  12. Column generation approaches to ship scheduling with flexible cargo sizes

    DEFF Research Database (Denmark)

    Brønmo, Geir; Nygreen, Bjørn; Lysgaard, Jens

    cargo sizes to the column generation framework is not straightforward, and we handle the flexible cargo sizes heuristically when solving the subproblems. This leads to convergence issues in the branch-and-price search tree, and the optimal solution cannot be guaranteed. Hence we have introduced a method...... that generates an upper bound on the optimal objective. We have compared our method with an a priori column generation approach, and our computational experiments on real world cases show that the Dantzig-Wolfe approach is faster than the a priori generation of columns, and we are able to deal with larger...

  13. 49 CFR 178.347 - Specification DOT 407; cargo tank motor vehicle.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 407; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.347 Specification DOT 407; cargo tank motor vehicle....

  14. 49 CFR 178.346 - Specification DOT 406; cargo tank motor vehicle.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 406; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.346 Specification DOT 406; cargo tank motor vehicle....

  15. 49 CFR 178.348 - Specification DOT 412; cargo tank motor vehicle.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification DOT 412; cargo tank motor vehicle... SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.348 Specification DOT 412; cargo tank motor vehicle....

  16. Waste inspection tomography (WIT)

    Energy Technology Data Exchange (ETDEWEB)

    Bernardi, R.T. [Bio-Imaging Research, Inc., Lincolnshire, IL (United States)

    1995-10-01

    Waste Inspection Tomography (WIT) provides mobile semi-trailer mounted nondestructive examination (NDE) and assay (NDA) for nuclear waste drum characterization. WIT uses various computed tomography (CT) methods for both NDE and NDA of nuclear waste drums. Low level waste (LLW), transuranic (TRU), and mixed radioactive waste can be inspected and characterized without opening the drums. With externally transmitted x-ray NDE techniques, WIT has the ability to identify high density waste materials like heavy metals, define drum contents in two- and three-dimensional space, quantify free liquid volumes through density and x-ray attenuation coefficient discrimination, and measure drum wall thickness. With waste emitting gamma-ray NDA techniques, WIT can locate gamma emitting radioactive sources in two- and three-dimensional space, identify gamma emitting, isotopic species, identify the external activity levels of emitting gamma-ray sources, correct for waste matrix attenuation, provide internal activity approximations, and provide the data needed for waste classification as LLW or TRU.

  17. 电子工业厂房洁净空调系统施工监理的控制要点%On controlling points for construction inspection for cleaning air-conditioner system of electronic industrial workshops

    Institute of Scientific and Technical Information of China (English)

    吕坤

    2015-01-01

    Combining with engineering cases,the paper analyzes the features of cleaning air-conditioner system of electronic industrial workshops, and illustrates the monitoring controlling points for the cleaning air-conditioner system of electronic industrial workshops from the materials and equipment entry,installation of air-conditioner wind system and air-conditioner water system,so as to enhance the cleaning air-conditioner system to achieve the expected effect.%结合工程案例,分析了电子工业洁净空调系统的特点,并从材料和设备进场、空调风系统安装、空调水系统安装三个方面出发,阐述了电子工业厂房洁净空调系统施工的监理控制要点,促使洁净空调系统达到预期的效果。

  18. 29 CFR 1918.83 - Stowed cargo; tiering and breaking down.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Stowed cargo; tiering and breaking down. 1918.83 Section... cargo; tiering and breaking down. (a) When necessary to protect personnel working in a hold, the employer shall secure or block stowed cargo that is likely to shift or roll. (b) In breaking down...

  19. 77 FR 21577 - Agency Information Collection Activities: Cargo Container and Road Vehicle Certification for...

    Science.gov (United States)

    2012-04-10

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Cargo Container and... collection requirement concerning the Cargo Container and Road Vehicle for Transport under Customs Seal. This...: Title: Cargo Container and Road Vehicle for Transport under Customs Seal. OMB Number: 1651-0124....

  20. 46 CFR 153.1000 - Special operating requirements for cargoes reactive with water.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Special operating requirements for cargoes reactive with water. 153.1000 Section 153.1000 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... MATERIALS Operations Special Cargo Procedures § 153.1000 Special operating requirements for cargoes...

  1. 46 CFR 153.935 - Opening of tanks and cargo sampling.

    Science.gov (United States)

    2010-10-01

    ..., except: (1) To clean a tank; (2) To transfer a cargo that Table 1 allows in a containment system having... 46 Shipping 5 2010-10-01 2010-10-01 false Opening of tanks and cargo sampling. 153.935 Section 153... Vessel Safety § 153.935 Opening of tanks and cargo sampling. (a) Except as provided in paragraph (b)...

  2. 33 CFR 126.27 - General permit for handling dangerous cargo.

    Science.gov (United States)

    2010-07-01

    ...) in bulk, portable tanks, containers, or packagings, at designated waterfront facilities, conditioned... cargo in limited-quantity packaging. (e) Transport units and portable tanks containing dangerous cargo... in the event of an accident. Cargo not required to be segregated, when in break-bulk form, is...

  3. Safety evaluation for packaging transport of LSA-II liquids in MC-312 cargo tanks

    Energy Technology Data Exchange (ETDEWEB)

    Carlstrom, R.F.

    1996-09-11

    This safety evaluation for packaging authorizes the onsite transfer of bulk LSA-II radioactive liquids in the 222-S Laboratory Cargo Tank and Liquid Effluent Treatment Facility Cargo Tanks (which are U.S. Department of Transportation MC-312 specification cargo tanks) from their operating facilities to tank farm facilities.

  4. 46 CFR 308.521 - Application for Open Cargo Policy, Form MA-301.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Application for Open Cargo Policy, Form MA-301. 308.521 Section 308.521 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR... for Open Cargo Policy, Form MA-301. The standard form of application for a War Risk Open Cargo...

  5. 46 CFR 154.650 - Cargo tank and process pressure vessel welding.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo tank and process pressure vessel welding. 154.650... Equipment Construction § 154.650 Cargo tank and process pressure vessel welding. (a) Cargo tank and process pressure vessel welding must meet Subpart 54.05 and Part 57 of this chapter. (b) Welding consumables...

  6. 76 FR 4847 - Hazardous Materials: Safety Requirements for External Product Piping on Cargo Tanks Transporting...

    Science.gov (United States)

    2011-01-27

    ...: Safety Requirements for External Product Piping on Cargo Tanks Transporting Flammable Liquids AGENCY... flammable liquids in unprotected external product piping on DOT specification cargo tank motor vehicles. If... specification cargo tank motor vehicle (CTMV), unless the vehicle is equipped with bottom damage...

  7. 77 FR 3487 - Agency Information Collection Activities: Transfer of Cargo to a Container Station

    Science.gov (United States)

    2012-01-24

    ... Information Collection Activities: Transfer of Cargo to a Container Station AGENCY: U.S. Customs and Border... information collection requirement concerning Transfer of Cargo to a Container Station. This request for...: Title: Transfer of Cargo to a Container Station. OMB Number: 1651-0096. Form Number: None....

  8. Study on Alternative Cargo Launch Options from the Lunar Surface

    Energy Technology Data Exchange (ETDEWEB)

    Cheryl A. Blomberg; Zamir A. Zulkefli; Spencer W. Rich; Steven D. Howe

    2013-07-01

    In the future, there will be a need for constant cargo launches from Earth to Mars in order to build, and then sustain, a Martian base. Currently, chemical rockets are used for space launches. These are expensive and heavy due to the amount of necessary propellant. Nuclear thermal rockets (NTRs) are the next step in rocket design. Another alternative is to create a launcher on the lunar surface that uses magnetic levitation to launch cargo to Mars in order to minimize the amount of necessary propellant per mission. This paper investigates using nuclear power for six different cargo launching alternatives, as well as the orbital mechanics involved in launching cargo to a Martian base from the moon. Each alternative is compared to the other alternative launchers, as well as compared to using an NTR instead. This comparison is done on the basis of mass that must be shipped from Earth, the amount of necessary propellant, and the number of equivalent NTR launches. Of the options, a lunar coil launcher had a ship mass that is 12.7% less than the next best option and 17 NTR equivalent launches, making it the best of the presented six options.

  9. 49 CFR 173.318 - Cryogenic liquids in cargo tanks.

    Science.gov (United States)

    2010-10-01

    ... temperature (one pound of water=27.737 cubic inches at 60 °F., or one gallon of water = 231 cubic inches at 60... density following partial unloading. Multiple OWTT markings for different pressure levels are permitted... the design service temperature of the packaging. (2) A cargo tank may not be loaded with any...

  10. 19 CFR 4.62 - Accounting for inward cargo.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Accounting for inward cargo. 4.62 Section 4.62 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY VESSELS IN FOREIGN AND DOMESTIC TRADES Foreign Clearances § 4.62 Accounting for inward...

  11. Bicaudal-D: Switching motors, cargo and direction

    NARCIS (Netherlands)

    G.D. Splinter (Daniël)

    2008-01-01

    textabstractScope of this thesis Transport of vesicles and organelles is an essential cellular process. Proteins like Rab GTPases, specialized adaptor proteins and motor proteins are involved in targeting and movement of cargos to their destination. This thesis describes the function of the mammalia

  12. 33 CFR 157.132 - Cargo tanks: Hydrocarbon vapor emissions.

    Science.gov (United States)

    2010-07-01

    ...(a)(2) or § 157.10c(b)(2) without sufficient segregated ballast tanks or dedicated clean ballast... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Cargo tanks: Hydrocarbon vapor... SECURITY (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK...

  13. 33 CFR 157.35 - Ballast added to cargo tanks.

    Science.gov (United States)

    2010-07-01

    ... segregated ballast tanks or dedicated clean ballast tanks under § 157.09, § 157.10, § 157.10a(a)(1), § 157...; (b) More ballast water than can be carried in segregated ballast tanks or dedicated clean ballast... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Ballast added to cargo tanks....

  14. A consolidation model for cargo-driven intermodal transportation

    NARCIS (Netherlands)

    Behdani, B.; Zuidwijk, R.A.

    2014-01-01

    Accessibility of main sea ports by road has become increasingly difficult due to rapid growth in container throughput. To deal with this challenge, new ways for handling containers and distribution of cargo flows are needed to define and implement. One possibility is going beyond container transport

  15. Integrated cargo routing and ship scheduling in liner shipping

    DEFF Research Database (Denmark)

    Kjeldsen, Karina Hjortshøj

    The problem consists of creating routes and schedules for a heterogeneous fleet of ships while determining the cargo routing and the speed for all relevant port pair/ship combinations. Transshipment is allowed in ports with transshipment capabilities. The service frequency is fixed at one week...

  16. CH-47F Improved Cargo Helicopter (CH-47F)

    Science.gov (United States)

    2015-12-01

    supply chain and industrial base. Nuclear Costs None CH-47F December 2015 SAR March 21, 2016 18:18:21 UNCLASSIFIED 22 Unit Cost Unit Cost Report...mission is transportation of ground forces, Class III/Class V supplies , and other battle critical cargo in support of all future contingencies. The CH

  17. 49 CFR 175.75 - Quantity limitations and cargo location.

    Science.gov (United States)

    2010-10-01

    ... CFR 25.857(b) or for a Class C aircraft cargo compartment in 14 CFR 25.857(c). A package bearing a KEEP AWAY FROM HEAT handling marking must be protected from direct sunshine and stored in a cool and ventilated place, away from sources of heat. (c) For each package containing a hazardous material...

  18. Mars Hybrid Propulsion System Trajectory Analysis. Part II; Cargo Missions

    Science.gov (United States)

    Chai, Patrick R.; Merrill, Raymond G.; Qu, Min

    2015-01-01

    NASA's Human Spaceflight Architecture Team is developing a reusable hybrid transportation architecture in which both chemical and electric propulsion systems are used to send crew and cargo to Mars destinations such as Phobos, Deimos, the surface of Mars, and other orbits around Mars. By combining chemical and electrical propulsion into a single spaceship and applying each where it is more effective, the hybrid architecture enables a series of Mars trajectories that are more fuel-efficient than an all chemical architecture without significant increases in flight times. This paper shows the feasibility of the hybrid transportation architecture to pre-deploy cargo to Mars and Phobos in support of the Evolvable Mars Campaign crew missions. The analysis shows that the hybrid propulsion stage is able to deliver all of the current manifested payload to Phobos and Mars through the first three crew missions. The conjunction class trajectory also allows the hybrid propulsion stage to return to Earth in a timely fashion so it can be reused for additional cargo deployment. The 1,100 days total trip time allows the hybrid propulsion stage to deliver cargo to Mars every other Earth-Mars transit opportunity. For the first two Mars surface mission in the Evolvable Mars Campaign, the short trip time allows the hybrid propulsion stage to be reused for three round-trip journeys to Mars, which matches the hybrid propulsion stage's designed lifetime for three round-trip crew missions to the Martian sphere of influence.

  19. Linac based photofission inspection system employing novel detection concepts

    Science.gov (United States)

    Stevenson, John; Gozani, Tsahi; Elsalim, Mashal; Condron, Cathie; Brown, Craig

    2011-10-01

    Rapiscan Systems is developing a LINAC based cargo inspection system for detection of special nuclear material (SNM) in cargo containers. The system, called Photofission Based Alarm Resolution (PBAR) is being developed under a DHD/DNDO Advanced Technology Demonstration (ATD) program. The PBAR system is based on the Rapiscan Eagle P9000 X-ray system, which is a portal system with a commercial 9 MeV LINAC X-ray source. For the purposes of the DNDO ATD program, a conveyor system was installed in the portal to allow scanning and precise positioning of 20 ft ISO cargo containers. The system uses a two step inspection process. In the first step, the basic scan, the container is quickly and completely inspected using two independent radiography arrays: the conventional primary array with high spatial resolution and a lower resolution spectroscopic array employing the novel Z-Spec method. The primary array uses cadmium tungstate (CdWO 4) detectors with conventional current mode readouts using photodiodes. The Z-Spec array uses small plastic scintillators capable of performing very fast (up to 10 8 cps) gamma-ray spectroscopy. The two radiography arrays are used to locate high-Z objects in the image such as lead, tungsten, uranium, which could be potential shielding materials as well as SNM itself. In the current system, the Z-Spec works by measuring the energy spectrum of transmitted X-rays. For high-Z materials the higher end of the energy spectrum is more attenuated than for low-Z materials and thus has a lower mean energy and a narrower width than low- and medium-Z materials. The second step in the inspection process is the direct scan or alarm clearing scan. In this step, areas of the container image, which were identified as high Z, are re-inspected. This is done by precisely repositioning the container to the location of the high-Z object and performing a stationary irradiation of the area with X-ray beam. Since there are a large number of photons in the 9 MV

  20. Industrial Inspection System

    Science.gov (United States)

    1993-01-01

    ACTIS+ is a smaller, personal computer version of ACTIS, a computed tomography system which finds its origins in the Apollo lunar landing research. It is used to identify imperfections in aerospace structures and components. Designed to be added to an existing real time radiography system, its components include a high precision rotation/elevation manipulator, color image monitor, graphical user interface monitor, and PC compatible workstation. Cross-sectional CT images are more detailed than radiographic images and the high speed scanning feature offers the capability for 100 percent inspection in a production environment. Bio-Imaging Research, Inc. (BIR) originally developed ACTIS for Marshall Space Flight Center (MSFC), and commercial units were sold to aerospace manufacturers. The technology was refined for ACTIS+, which is principally used in non-destructive testing.

  1. Labor inspection in Brazil

    Directory of Open Access Journals (Sweden)

    Adalberto Cardoso

    2006-01-01

    Full Text Available One aspect the literature overlooks on the effects of labor regulation of labor market efficiency is the degree of the legislation's effectiveness, i.e., its actual enforcement in daily work relations. Even the more sophisticated econometric studies (which take into account the effects of interaction between labor market regulatory institutions in explaining its dynamics leave this central issue aside, namely enforcement versus non-enforcement of the law. Keeping this issue in mind, we seek to answer the following question in this article: given that the effectiveness of labor legislation depends on the interaction between the overall sanctions and the probability of the employer getting caught breaking the law, and given that the law's effectiveness is a decisive aspect for the real measurement of a country's labor costs, to what extent is the Brazilian labor inspection system designed to meet its objective, namely, to enforce the law?

  2. Simplified Approach to Inspection Planning

    DEFF Research Database (Denmark)

    Bloch, Allan; Sørensen, John Dalsgaard; Faber, M. H.

    2000-01-01

    A simplified and practically applicable approach for risk based inspection planning of fatigue sensitive structural details is presented. The basic idea behind the approach is that the fatigue sensitive details are categorized according to their stress intensity factors and their design fatigue l...... of steel structures. The validity of the proposed approach is illustrated through a study regarding inspection planning of offshore structures....... life to service life ratio, i.e. the fatigue design factor (FDF) and SN curve. When the reserve strength ratio (RSR) and the corresponding probability of total structural failure given fatigue failure of the considered detail is known it is possible to make a generic description of fatigue sensitive...... structural details and thereby develop pre-made inspection plans in tables which depend on relative cost of inspections, repairs and failures. Due to the simplicity of the format of the developed inspection plans the proposed approach has a high potential in code making for the design and maintenance...

  3. 9 CFR 381.68 - Maximum inspection rates-New turkey inspection system.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Maximum inspection rates-New turkey inspection system. 381.68 Section 381.68 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE... Procedures § 381.68 Maximum inspection rates—New turkey inspection system. (a) The maximum inspection...

  4. Principles and status of neutron-based inspection technologies

    Science.gov (United States)

    Gozani, Tsahi

    2011-06-01

    Nuclear based explosive inspection techniques can detect a wide range of substances of importance for a wide range of objectives. For national and international security it is mainly the detection of nuclear materials, explosives and narcotic threats. For Customs Services it is also cargo characterization for shipment control and customs duties. For the military and other law enforcement agencies it could be the detection and/or validation of the presence of explosive mines, improvised explosive devices (IED) and unexploded ordnances (UXO). The inspection is generally based on the nuclear interactions of the neutrons (or high energy photons) with the various nuclides present and the detection of resultant characteristic emissions. These can be discrete gamma lines resulting from the thermal neutron capture process (n,γ) or inelastic neutron scattering (n,n'γ) occurring with fast neutrons. The two types of reactions are generally complementary. The capture process provides energetic and highly penetrating gamma rays in most inorganic substances and in hydrogen, while fast neutron inelastic scattering provides relatively strong gamma-ray signatures in light elements such as carbon and oxygen. In some specific important cases unique signatures are provided by the neutron capture process in light elements such as nitrogen, where unusually high-energy gamma ray is produced. This forms the basis for key explosive detection techniques. In some cases the elastically scattered source (of mono-energetic) neutrons may provide information on the atomic weight of the scattering elements. The detection of nuclear materials, both fissionable (e.g., 238U) and fissile (e.g., 235U), are generally based on the fissions induced by the probing neutrons (or photons) and detecting one or more of the unique signatures of the fission process. These include prompt and delayed neutrons and gamma rays. These signatures are not discrete in energy (typically they are continua) but temporally

  5. Mechanized silica nanoparticles based on pillar[5]arenes for on-command cargo release.

    Science.gov (United States)

    Sun, Yu-Long; Yang, Ying-Wei; Chen, Dai-Xiong; Wang, Guan; Zhou, Yue; Wang, Chun-Yu; Stoddart, J Fraser

    2013-10-11

    Mechanized silica nanoparticles, equipped with pillar[5]arene-[2]pseudorotaxane nanovalves, operate in biological media to trap cargos within their nanopores, but release them when the pH is lowered or a competitive binding agent is added. Although cargo size plays an important role in cargo loading, cargo charge-type does not appear to have any significant influence on the amount of cargo loading or its release. These findings open up the possibility of using pillar[n]arene and its derivatives for the formation of robust and dynamic nanosystems that are capable of performing useful functions.

  6. Detection of explosives, shielded nuclear materials and other hazardous substances in cargo containers

    Science.gov (United States)

    Kuznetsov, Andrey; Evsenin, Alexey; Vakhtin, Dmitry; Gorshkov, Igor; Osetrov, Oleg; Kalinin, Valery

    2006-05-01

    Nanosecond Neutron Analysis / Associated Particles Technique (NNA/APT) has been used to create devices for detection of explosives, radioactive and heavily shielded nuclear materials in cargo containers. Explosives and other hazardous materials are detected by analyzing secondary high-energy gamma-rays form reactions of fast neutrons with the materials inside the container. Depending on the dimensions of the inspected containers, the detecting system consists of one or several detection modules, each of which contains a small neutron generator with built-in position sensitive detector of associated alpha-particles and several scintillator-based gamma-ray detectors. The same gamma-ray detectors are used to detect unshielded radioactive and nuclear materials. Array of several detectors of fast neutrons is used to detect neutrons from spontaneous and induced fission of nuclear materials. These neutrons can penetrate thick layers of lead shielding, which can be used to conceal gamma-radioactivity from nuclear materials. Coincidence and timing analysis allows one to discriminate between fission neutrons and scattered probing neutrons. Mathematical modeling by MCNP5 code was used to estimate the sensitivity of the device and its optimal configuration. Capability of the device to detect 1 kg of explosive imitator inside container filled with suitcases and other baggage items has been confirmed experimentally. First experiments with heavily shielded nuclear materials have been carried out.

  7. 7 CFR 29.6002 - Air-cured.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Air-cured. 29.6002 Section 29.6002 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Standards Definitions § 29.6002 Air-cured. Tobacco cured under natural atmospheric...

  8. Codified Risk Based Inspection Planning

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Faber, M.H.

    2002-01-01

    and member failure and at the same time minimizing overall total service life costs. Generic inspections plans can then be established for representative fatigue sensitive details in terms of characteristics such as FDF (Fatigue Design Factor), detail type, RSR (Reserve Strength Ratio) given fatigue failure......Simplified methods are described for reliability- and risk-based inspection planning of steel structures. The methods simplify the practical aspects of identifying inspection plans complying both with specific requirements to the maximum acceptable annual probability of structural collapse...

  9. Advanced propulsion options for the Mars cargo mission

    Science.gov (United States)

    Frisbee, Robert H.; Blandino, John J.; Sercel, Joel C.; Sargent, Mark S.; Gowda, Nandini

    1990-01-01

    Several advanced propulsion options for a split-mission piloted Mars exploration scenario are presented. The primary study focus is on identifying concepts that can reduce total initial mass in low earth orbit (IMLEO) for the cargo delivery portion of the mission; in addition, concepts that can reduce the trip time of the piloted option are assessed. The propulsion options considered are nuclear thermal propulsion, solar sails, multimegawatt-class nuclear electric propulsion, solar electric propulsion, magnetic sails, mass drivers, rail guns, solar thermal rockets, beamed-energy propulsion systems, and tethers. For the cargo mission, solar sails are found to provide the greatest mass savings over the baseline chemical system, although they suffer from having very long trip times; a good performance compromise between a low IMLEO and a short trip time can be obtained using multimegawatt-class nuclear electric propulsion systems.

  10. Implementation of cargo MagLev in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Rose, Chris R [Los Alamos National Laboratory; Peterson, Dean E [Los Alamos National Laboratory; Leung, Eddie M [MAGTEC ENGINEERING

    2008-01-01

    Numerous studies have been completed in the United States, but no commercial MagLev systems have been deployed. Outside the U.S., MagLev continues to attract funding for research, development and implementation. A brief review of recent global developments in MagLev technology is given followed by the status of MagLev in the U.S. The paper compares the cost of existing MagLev systems with other modes of transport, notes that the near-term focus of MagLev development in the U.S. should be for cargo, and suggests that future MagLev systems should be for very high speed cargo. The Los Angeles to Port of Los Angeles corridor is suggested as a first site for implementation. The benefits of MagLev are described along with suggestions on how to obtain funding.

  11. Variable Structure Control of Catastrophic Course in Airdropping Heavy Cargo

    Institute of Scientific and Technical Information of China (English)

    Zhang Huiyuan; Shi Zhongke

    2009-01-01

    The mathematical model of a transport aircraft would be subjected to a sudden change when heavy cargo is dropped off in airdropping, which exerts serious influences upon the safety of the aircraft. A variable structure controller is specially designed for handling the airdrop process. The nonlinear system is linearized by input-output feedback linearization using differential geometry theories. On this basis, an inner loop system for velocity and attitude tracking control is designed by using the exponentially approaching rule of the variable structure theory. The whole flight control system is integrated with the outer loop flight altitude control. Digital simulation evidences the applicability of the system to potentially catastrophic course in airdropping heavy cargo and provides robustness against system parameter perturbation.

  12. The Liner Shipping Fleet Repositioning Problem with Cargo Flows

    DEFF Research Database (Denmark)

    Tierney, Kevin; Jensen, Rune Møller

    2012-01-01

    We solve an important problem for the liner shipping industry called the Liner Shipping Fleet Repositioning Problem (LSFRP). The LSFRP poses a large financial burden on liner shipping firms. During repositioning, vessels are moved between services in a liner shipping network. Shippers wish...... in the literature. We introduce a novel mathematical model of the LSFRP with cargo flows based on a carefully constructed graph and evaluate it on real world data from our industrial collaborator....

  13. August Passenger and Cargo Numbers Set New Highs

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Passenger and cargo numbers set new highs in August, the second consecutive month that both areas of operation at Dragonair posted record figures. The airline flew 444,498 passengers in August to record its third consecutive monthly record. The number was 7.7%higher than in July, with travel in both months driven by holiday traffic. August 15 saw a new daily mark set, with 17,220passengers carried on the day.

  14. Stokes Efficiency of Molecular Motor-Cargo Systems

    Science.gov (United States)

    2008-01-01

    2655, 1994. 11 F. Reif , Fundamentals of Statistical and Thermal Physics, McGraw-Hill, New York, NY, USA, 1985. 12 H. Kleinert, Path Integrals in...Quantum Mechanics , Statistics , Polymer Physics, and Financial Markets, World Scientific, River Edge, NJ, USA, 3rd edition, 2004. 13 A. Einstein...Efficiency of Molecular Motor-Cargo Systems Hongyun Wang1 and Hong Zhou2 1Department of Applied Mathematics and Statistics , University of California

  15. The Application Model of Moving Objects in Cargo Delivery System

    Institute of Scientific and Technical Information of China (English)

    ZHANG Feng-li; ZHOU Ming-tian; XU Bo

    2004-01-01

    The development of spatio-temporal database systems is primarily motivated by applications which track and present mobile objects. In this paper, solutions for establishing the moving object database based on GPS/GIS environment are presented, and a data modeling of moving object is given by using Temporal logical to extent the query language, finally the application model in cargo delivery system is shown.

  16. Radioactive material air transportation; Transporte aereo de material radioativo

    Energy Technology Data Exchange (ETDEWEB)

    Pader y Terry, Claudio Cosme [Varig Logistica (VARIGLOG), Sao Paulo, SP (Brazil)

    2002-07-01

    As function of the high aggregated value, safety regulations and the useful life time, the air transportation has been used more regularly because is fast, reliable, and by giving great security to the cargo. Based on the International Atomic Energy Agency (IAEA), the IATA (International Air Transportation Association) has reproduced in his dangerous goods manual (Dangerous Goods Regulations - DGR IATA), the regulation for the radioactive material air transportation. Those documents support this presentation.

  17. Cargo transport by cytoplasmic Dynein can center embryonic centrosomes.

    Directory of Open Access Journals (Sweden)

    Rafael A Longoria

    Full Text Available To complete meiosis II in animal cells, the male DNA material needs to meet the female DNA material contained in the female pronucleus at the egg center, but it is not known how the male pronucleus, deposited by the sperm at the periphery of the cell, finds the cell center in large eggs. Pronucleus centering is an active process that appears to involve microtubules and molecular motors. For small and medium-sized cells, the force required to move the centrosome can arise from either microtubule pushing on the cortex, or cortically-attached dynein pulling on microtubules. However, in large cells, such as the fertilized Xenopus laevis embryo, where microtubules are too long to support pushing forces or they do not reach all boundaries before centrosome centering begins, a different force generating mechanism must exist. Here, we present a centrosome positioning model in which the cytosolic drag experienced by cargoes hauled by cytoplasmic dynein on the sperm aster microtubules can move the centrosome towards the cell's center. We find that small, fast cargoes (diameter ∼100 nm, cargo velocity ∼2 µm/s are sufficient to move the centrosome in the geometry of the Xenopus laevis embryo within the experimentally observed length and time scales.

  18. Diffusion-Limited Cargo Loading of an Engineered Protein Container.

    Science.gov (United States)

    Zschoche, Reinhard; Hilvert, Donald

    2015-12-30

    The engineered bacterial nanocompartment AaLS-13 is a promising artificial encapsulation system that exploits electrostatic interactions for cargo loading. In order to study its ability to take up and retain guests, a pair of fluorescent proteins was developed which allows spectroscopic determination of the extent of encapsulation by Förster resonance energy transfer (FRET). The encapsulation process is generally complete within a second, suggesting low energetic barriers for proteins to cross the capsid shell. Formation of intermediate aggregates upon mixing host and guest in vitro complicates capsid loading at low ionic strength, but can be sidestepped by increasing salt concentrations or diluting the components. Encapsulation of guests is completely reversible, and the position of the equilibrium is easily tuned by varying the ionic strength. These results, which challenge the notion that AaLS-13 is a continuous rigid shell, provide valuable information about cargo loading that will guide ongoing efforts to engineer functional host-guest complexes. Moreover, it should be possible to adapt the protein FRET pair described in this report to characterize functional capsid-cargo complexes generated by other encapsulation systems.

  19. Public Housing Physical Inspection Scores

    Data.gov (United States)

    Department of Housing and Urban Development — HUD's Real Estate Assessment Center conducts physical property inspections of properties that are owned, insured or subsidized by HUD, including public housing and...

  20. Multifamily Housing Physical Inspection Scores

    Data.gov (United States)

    Department of Housing and Urban Development — HUD's Real Estate Assessment Center conducts physical property inspections of properties that are owned, insured or subsidized by HUD, including public housing and...

  1. National Automated Conformity Inspection Process -

    Data.gov (United States)

    Department of Transportation — The National Automated Conformity Inspection Process (NACIP) Application is intended to expedite the workflow process as it pertains to the FAA Form 81 0-10 Request...

  2. Sea bed mapping and inspection

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The conference has 24 presentations on the topics: Sea bed mapping, inspection, positioning, hydrography, marine archaeology, remote operation vehicles and computerized simulation technologies, oil field activities and plans, technological experiences and problems. (tk)

  3. United States Air Force Statistical Digest, Fiscal Year 1979, Thirty-Fourth Edition

    Science.gov (United States)

    1980-06-30

    Force Simpson Historical Research Center Air Force Service Information and News Center Air Force Intelligence Service. Air Force Inspection and Saftey ...Examination (Standard Form 88); physical inspections of food handlers or barbers are not included nor are examina- tions of personnel who are ill

  4. How molecular motors are arranged on a cargo is important for vesicular transport.

    Science.gov (United States)

    Erickson, Robert P; Jia, Zhiyuan; Gross, Steven P; Yu, Clare C

    2011-05-01

    The spatial organization of the cell depends upon intracellular trafficking of cargos hauled along microtubules and actin filaments by the molecular motor proteins kinesin, dynein, and myosin. Although much is known about how single motors function, there is significant evidence that cargos in vivo are carried by multiple motors. While some aspects of multiple motor function have received attention, how the cargo itself--and motor organization on the cargo--affects transport has not been considered. To address this, we have developed a three-dimensional Monte Carlo simulation of motors transporting a spherical cargo, subject to thermal fluctuations that produce both rotational and translational diffusion. We found that these fluctuations could exert a load on the motor(s), significantly decreasing the mean travel distance and velocity of large cargos, especially at large viscosities. In addition, the presence of the cargo could dramatically help the motor to bind productively to the microtubule: the relatively slow translational and rotational diffusion of moderately sized cargos gave the motors ample opportunity to bind to a microtubule before the motor/cargo ensemble diffuses out of range of that microtubule. For rapidly diffusing cargos, the probability of their binding to a microtubule was high if there were nearby microtubules that they could easily reach by translational diffusion. Our simulations found that one reason why motors may be approximately 100 nm long is to improve their 'on' rates when attached to comparably sized cargos. Finally, our results suggested that to efficiently regulate the number of active motors, motors should be clustered together rather than spread randomly over the surface of the cargo. While our simulation uses the specific parameters for kinesin, these effects result from generic properties of the motors, cargos, and filaments, so they should apply to other motors as well.

  5. How molecular motors are arranged on a cargo is important for vesicular transport.

    Directory of Open Access Journals (Sweden)

    Robert P Erickson

    2011-05-01

    Full Text Available The spatial organization of the cell depends upon intracellular trafficking of cargos hauled along microtubules and actin filaments by the molecular motor proteins kinesin, dynein, and myosin. Although much is known about how single motors function, there is significant evidence that cargos in vivo are carried by multiple motors. While some aspects of multiple motor function have received attention, how the cargo itself--and motor organization on the cargo--affects transport has not been considered. To address this, we have developed a three-dimensional Monte Carlo simulation of motors transporting a spherical cargo, subject to thermal fluctuations that produce both rotational and translational diffusion. We found that these fluctuations could exert a load on the motor(s, significantly decreasing the mean travel distance and velocity of large cargos, especially at large viscosities. In addition, the presence of the cargo could dramatically help the motor to bind productively to the microtubule: the relatively slow translational and rotational diffusion of moderately sized cargos gave the motors ample opportunity to bind to a microtubule before the motor/cargo ensemble diffuses out of range of that microtubule. For rapidly diffusing cargos, the probability of their binding to a microtubule was high if there were nearby microtubules that they could easily reach by translational diffusion. Our simulations found that one reason why motors may be approximately 100 nm long is to improve their 'on' rates when attached to comparably sized cargos. Finally, our results suggested that to efficiently regulate the number of active motors, motors should be clustered together rather than spread randomly over the surface of the cargo. While our simulation uses the specific parameters for kinesin, these effects result from generic properties of the motors, cargos, and filaments, so they should apply to other motors as well.

  6. Virtual World Security Inspection

    Directory of Open Access Journals (Sweden)

    Nicholas Charles Patterson

    2012-06-01

    Full Text Available Virtual property theft is a serious problem that exists in virtual worlds. Legitimate users of these worlds invest considerable amounts of time, effort and real-world money into obtaining virtual property, but unfortunately, are becoming victims of theft in high numbers. It is reported that there are over 1 billion registered users of virtual worlds containing virtual property items worth an estimated US$50 billion dollars. The problem of virtual property theft is complex, involving many legal, social and technological issues. The software used to access virtual worlds is of great importance as they form the primary interface to these worlds and as such the primary interface to conduct virtual property theft. The security vulnerabilities of virtual world applications have not, to date, been examined. This study aims to use the process of software inspection to discover security vulnerabilities that may exist within virtual world software – vulnerabilities that enable virtual property theft to occur. Analyzing three well know virtual world applications World of Warcraft, Guild Wars and Entropia Universe, this research utilized security analysis tools and scenario testing with focus on authentication, trading, intruder detection and virtual property recovery. It was discovered that all three examples were susceptible to keylogging, mail and direct trade methods were the most likely method for transferring stolen items, intrusion detection is of critical concern to all VWEs tested, stolen items were unable to be recovered in all cases and lastly occurrences of theft were undetectable in all cases. The results gained in this study present the key problem areas which need to be addressed to improve security and reduce the occurrence of virtual property theft.

  7. 46 CFR 61.30-15 - Visual inspection.

    Science.gov (United States)

    2010-10-01

    ... INSPECTIONS Tests and Inspections of Fired Thermal Fluid Heaters § 61.30-15 Visual inspection. Thermal fluid heaters are examined by a marine inspector at the inspection for certification, periodic inspection...

  8. 23 CFR 650.311 - Inspection frequency.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Inspection frequency. 650.311 Section 650.311 Highways..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.311 Inspection frequency. (a) Routine... level and frequency to which these bridges are inspected considering such factors as age,...

  9. Challenges Faced in Modern Quality Inspection

    Directory of Open Access Journals (Sweden)

    Borkowski Stanisław

    2016-09-01

    Full Text Available Point of view, preferences and priorities of quality inspection in modern production systems have changed. Quality inspection in its activities is no longer limited only to the documentation of the past, nor is it seen solely as a tool for the detection of nonconformity. Nowadays, the most important quality inspection function is prevention, whose most important goal is to make it before nonconformity. What is expected from modern quality inspection is that it actively improves the production and quality as well as reduces the costs. The aim of the article is to present requirements, guidelines and challenges in the organization of modern quality inspection in a manufacturing company. The role of quality inspection in the classical model and modern model of quality improvement was presented. Determinants of effective quality inspection were presented, as well. The quality inspection methods that best fit into the paradigm of modern quality inspection, that is source inspection, together with visual management were pointed out.

  10. ROBOTIC TANK INSPECTION END EFFECTOR

    Energy Technology Data Exchange (ETDEWEB)

    Rachel Landry

    1999-10-01

    The objective of this contract between Oceaneering Space Systems (OSS) and the Department of Energy (DOE) was to provide a tool for the DOE to inspect the inside tank walls of underground radioactive waste storage tanks in their tank farms. Some of these tanks are suspected to have leaks, but the harsh nature of the environment within the tanks precludes human inspection of tank walls. As a result of these conditions only a few inspection methods can fulfill this task. Of the methods available, OSS chose to pursue Alternating Current Field Measurement (ACFM), because it does not require clean surfaces for inspection, nor any contact with the Surface being inspected, and introduces no extra by-products in the inspection process (no coupling fluids or residues are left behind). The tool produced by OSS is the Robotic Tank Inspection End Effector (RTIEE), which is initially deployed on the tip of the Light Duty Utility Arm (LDUA). The RTEE combines ACFM with a color video camera for both electromagnetic and visual inspection The complete package consists of an end effector, its corresponding electronics and software, and a user's manual to guide the operator through an inspection. The system has both coarse and fine inspection modes and allows the user to catalog defects and suspected areas of leakage in a database for further examination, which may lead to emptying the tank for repair, decommissioning, etc.. The following is an updated report to OSS document OSS-21100-7002, which was submitted in 1995. During the course of the contract, two related subtasks arose, the Wall and Coating Thickness Sensor and the Vacuum Scarifying and Sampling Tool Assembly. The first of these subtasks was intended to evaluate the corrosion and wall thinning of 55-gallon steel drums. The second was retrieved and characterized the waste material trapped inside the annulus region of the underground tanks on the DOE's tank farms. While these subtasks were derived from the original

  11. The Analysis of Significance of the Establishment of Cathay Pacific Cargo New Terminal%国泰航空新货运站建成的意义分析

    Institute of Scientific and Technical Information of China (English)

    施磊

    2015-01-01

    2013年2月,备受货运界瞩目的国泰航空公司新货运站正式启用。新货运站集尖端设备于一身,年货物处理量达260万吨,预示着香港国际机场的货物处理能力更上一层楼。与此同时,新货运站的建立可降低成本,平摊风险,不失为新的利润增长点。航空运输仅仅是航空货运价值链中的一个环节,新货运站是国泰货运价值链的延伸,只有对众多的环节进行有效控制,才能满足客户对完整货物运输产品的需求。未来的航空货运界将更加激烈,筹建货运站将是航空公司抢占先机的突破口。文章具体分析了国泰航空新货运站建成的意义。%In February of 2013, the high-profile cargo terminal of Cathay Pacific Airways was put into service, with a set of sophisticated equipment, the new cargo terminal has the handling capacity of 2600000 tons, which indicates that the cargo handling capacity of Hong Kong International Airport reaches a higher level. At the same time, the establishment of the new cargo terminal can reduce cost, share risk, and also can be regarded as a new profit growth point. Air transportation is only a link in the value chain of air transportation, and the new cargo terminal is the extension of Cathay Pacific cargo value chain, only if the links is being controlled effectively, customer demand for complete freight transport can be met. The future of the air cargo industry will become more intense, the establishment of cargo terminal will be a breakthrough to win the opportunity.

  12. 49 CFR 180.413 - Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks.

    Science.gov (United States)

    2010-10-01

    ... carbon dioxide, service are excepted from these testing requirements, but must be tested in accordance... rebuilt cargo tank's structural integrity, venting, and accident damage protection with the...

  13. 75 FR 64585 - Bulk Solid Hazardous Materials: Harmonization With the International Maritime Solid Bulk Cargoes...

    Science.gov (United States)

    2010-10-19

    ... nonsubstantive changes, however, to correct grammar, internal paragraph references, and a temperature conversion... means the English version of the ``International Maritime Solid Bulk Cargoes Code'' published by...

  14. ATHLETE: Lunar Cargo Handling for International Lunar Exploration

    Science.gov (United States)

    Wilcox, Brian H.

    2010-01-01

    As part of the Human-Robot Systems Project within the NASA Exploration Technology Development Program, the Jet Propulsion Laboratory is developing a vehicle called ATHLETE: the All-Terrain Hex-Limbed Extra-Terrestrial Explorer. The basic idea of ATHLETE is to have six relatively small wheels on the ends of legs. The small wheels and associated drive actuators are much less massive than the larger wheels and gears needed for an "all terrain" vehicle that cannot "walk" out of extreme terrain. The mass savings for the wheels and wheel actuators is greater than the mass penalty of the legs, for a net mass savings. Starting in 2009, NASA became engaged in detailed architectural studies for international discussions with the European Space Agency (ESA), the Japanese Space Agency (JAXA), and the Canadian Space Agency (CSA) under the auspices of the International Architecture Working Group (IAWG). ATHLETE is considered in most of the campaign options considered, providing a way to offload cargo from large Altair-class landers (having a cargo deck 6+ meters above the surface) as well as offloading international landers launched on Ariane-5 or H-2 launch vehicles. These international landers would carry provisions as well as scientific instruments and/or small rovers that would be used by international astronauts as part of an international effort to explore the moon.Work described in this paper includes architectural studies in support of the international missions as well as field testing of a half-scale ATHLETE prototype performing cargo offloading from a lander mockup, along with multi-kilometer traverse, climbing over greater than 1 m rocks, tool use, etc.

  15. Solving the Liner Shipping Fleet Repositioning Problem with Cargo Flows

    DEFF Research Database (Denmark)

    Tierney, Kevin; Askelsdottir, Björg; Jensen, Rune Møller

    2015-01-01

    We solve a central problem in the liner shipping industry called the liner shipping fleet repositioning problem (LSFRP). The LSFRP poses a large financial burden on liner shipping firms. During repositioning, vessels are moved between routes in a liner shipping network. Liner carriers wish...... introduce a novel mathematical model and a simulated annealing algorithm for the LSFRP with cargo flows that makes use of a carefully constructed graph; we evaluate these approaches using real-world data from our industrial collaborator. Additionally, we compare the performance of our approach against...

  16. Collinear swimmer propelling a cargo sphere at low Reynolds number

    CERN Document Server

    Felderhof, B U

    2014-01-01

    The swimming velocity and rate of dissipation of a linear chain consisting of two or three little spheres and a big sphere is studied on the basis of low Reynolds number hydrodynamics. The big sphere is treated as a passive cargo, driven by the tail of little spheres via hydrodynamic and direct elastic interaction. The fundamental solution of Stokes' equations in the presence of a sphere with no-slip boundary condition, as derived by Oseen, is used to model the hydrodynamic interactions between the big sphere and the little spheres.

  17. Autonomous underwater riser inspection tool

    Energy Technology Data Exchange (ETDEWEB)

    Camerini, Claudio; Marnet, Robson [Petrobras SA, (Brazil); Freitas, Miguel; Von der Weid, Jean Pierre [CPTI/PUC-Rio, Rio de Janeiro, (Brazil); Artigas Lander, Ricardo [EngeMOVI, Curitiba, (Brazil)

    2010-07-01

    The detection of damage on the riser is a serious concern for pipeline companies. Visual examinations by remotely operated vehicle (ROV) are presently carried out to detect the defects but this process has limitations and is expensive. This paper presents the development of a new tool to ensure autonomous underwater riser inspection (AURI) that uses the riser itself for guidance. The AURI, which is autonomous in terms of control and power supply, is equipped with several cameras that perform a complete visual inspection of the riser with 100 % coverage of the external surface of the riser. The paper presents the detailed characteristics of the first AURI prototype, describes its launching procedure and provides the preliminary test results from pool testing. The results showed that the AURI is a viable system for autonomous riser inspection. Offshore tests on riser pipelines are scheduled to be performed shortly.

  18. Evaluation of inservice inspection examinatiions

    Energy Technology Data Exchange (ETDEWEB)

    Aldrich, D.A.; Cook, J.F.

    1990-05-01

    In order to evaluate the effectiveness of Section 11, Division 1, Rules for Inservice Inspection of Nuclear Power Plant Components,'' of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code examinations, 26 inservice inspection (ISI) summary reports from 24 facilities were reviewed. It was found that these ASME Code examinations and tests are instrumental in revealing indications and defects in welds and plant components. In addition, this study uncovered that fact that some of the Section 11 requirements are apparently not clear and are misunderstood by some of the facilities. Also, the need for more stringent requirements was evaluated and some Code changes are recommended.

  19. Evaluation of inservice inspection examinatiions

    Energy Technology Data Exchange (ETDEWEB)

    Aldrich, D.A.; Cook, J.F.

    1990-05-01

    In order to evaluate the effectiveness of Section 11, Division 1, ``Rules for Inservice Inspection of Nuclear Power Plant Components,`` of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code examinations, 26 inservice inspection (ISI) summary reports from 24 facilities were reviewed. It was found that these ASME Code examinations and tests are instrumental in revealing indications and defects in welds and plant components. In addition, this study uncovered that fact that some of the Section 11 requirements are apparently not clear and are misunderstood by some of the facilities. Also, the need for more stringent requirements was evaluated and some Code changes are recommended.

  20. Planning Annual Shutdown Inspection for BFB Boiler

    OpenAIRE

    Sorsa, Tatu

    2014-01-01

    The goal of this thesis was to create an illustrative guidebook of annual inspection planning for BFB boiler to help power plant operator when planning of annual inspection is topical. This thesis was made for Andritz Oy and it is based on inspection reports and experiences of BFB boiler’s maintenance and inspection staff. In this thesis it is shown how to plan an annual inspection for BFB boiler and thesis gives good tools and hints for operator to manage inspection from the beginning ...

  1. Effect of fuel concentration on cargo transport by a team of Kinesin motors

    Science.gov (United States)

    Takshak, Anjneya; Mishra, Nirvantosh; Kulkarni, Aditi; Kunwar, Ambarish

    2017-02-01

    Eukaryotic cells employ specialized proteins called molecular motors for transporting organelles and vesicles from one location to another in a regulated and directed manner. These molecular motors often work collectively in a team while transporting cargos. Molecular motors use cytoplasmic ATP as fuel, which is hydrolyzed to generate mechanical force. While the effect of ATP concentration on cargo transport by single Kinesin motor function is well understood, it is still unexplored, both theoretically and experimentally, how ATP concentration would affect cargo transport by a team of Kinesin motors. For instance, how does fuel concentration affect the travel distances and travel velocities of cargo? How cooperativity of Kinesin motors engaged on a cargo is affected by ATP concentration? To answer these questions, here we develop mechano-chemical models of cargo transport by a team of Kinesin motors. To develop these models we use experimentally-constrained mechano-chemical model of a single Kinesin motor as well as earlier developed mean-field and stochastic models of load sharing for cargo transport. Thus, our new models for cargo transport by a team of Kinesin motors include fuel concentration explicitly, which was not considered in earlier models. We make several interesting predictions which can be tested experimentally. For instance, the travel distances of cargos are very large at limited ATP concentrations in spite of very small travel velocity. Velocities of cargos driven by multiple Kinesin have a Michaelis-Menten dependence on ATP concentration. Similarly, cooperativity among the engaged Kinesin motors on the cargo shows a Michaelis-Menten type dependence, which attains a maximum value near physiological ATP concentrations. Our new results can be potentially useful in controlling artificial nano-molecular shuttles precisely for targeted delivery in various nano-technological applications.

  2. Spatial partitioning of secretory cargo from Golgi resident proteins in live cells

    Directory of Open Access Journals (Sweden)

    White Jamie

    2001-10-01

    Full Text Available Abstract Background To maintain organelle integrity, resident proteins must segregate from itinerant cargo during secretory transport. However, Golgi resident enzymes must have intimate access to secretory cargo in order to carry out glycosylation reactions. The amount of cargo and associated membrane may be significant compared to the amount of Golgi membrane and resident protein, but upon Golgi exit, cargo and resident are efficiently sorted. How this occurs in live cells is not known. Results We observed partitioning of the fluorescent Golgi resident T2-CFP and fluorescent cargo proteins VSVG3-YFP or VSVG3-SP-YFP upon Golgi exit after a synchronous pulse of cargo was released from the ER. Golgi elements remained stable in overall size, shape and relative position as cargo emptied. Cargo segregated from resident rapidly by blebbing into micron-sized domains that contained little or no detectable resident protein and that appeared to be continuous with the parent Golgi element. Post-Golgi transport carriers (TCs exited repeatedly from these domains. Alternatively, entire cargo domains exited Golgi elements, forming large TCs that fused directly with the plasma membrane. However, domain formation did not appear to be an absolute prerequisite for TC exit, since TCs also exited directly from Golgi elements in the absence of large domains. Quantitative cargo-specific photobleaching experiments revealed transfer of cargo between Golgi regions, but no discrete intra-Golgi TCs were observed. Conclusions Our results establish domain formation via rapid lateral partitioning as a general cellular strategy for segregating different transmembrane proteins along the secretory pathway and provide a framework for consideration of molecular mechanisms of secretory transport.

  3. "Cargo-mooring" as an operating principle for molecular motors.

    Science.gov (United States)

    Lisowski, Bartosz; Kuśmierz, Łukasz; Żabicki, Michał; Bier, Martin

    2015-06-07

    Navigating through an ever-changing and unsteady environment, and utilizing chemical energy, molecular motors transport the cell׳s crucial components, such as organelles and vesicles filled with neurotransmitter. They generate force and pull cargo, as they literally walk along the polymeric tracks, e.g. microtubules. What we suggest in this paper is that the motor protein is not really pulling its load. The load is subject to diffusion and the motor may be doing little else than rectifying the fluctuations, i.e. ratcheting the load׳s diffusion. Below we present a detailed model to show how such ratcheting can quantitatively account for observed data. The consequence of such a mechanism is the dependence of the transport׳s speed and efficacy not only on the motor, but also on the cargo (especially its size) and on the environment (i.e. its viscosity and structure). Current experimental works rarely provide this type of information for in vivo studies. We suggest that even small differences between assays can impact the outcome. Our results agree with those obtained in wet laboratories and provide novel insight in a molecular motor׳s functioning.

  4. Achieving integrated convoys: cargo unmanned ground vehicle development and experimentation

    Science.gov (United States)

    Zych, Noah; Silver, David; Stager, David; Green, Colin; Pilarski, Thomas; Fischer, Jacob

    2013-05-01

    The Cargo UGV project was initiated in 2010 with the aim of developing and experimenting with advanced autonomous vehicles capable of being integrated unobtrusively into manned logistics convoys. The intent was to validate two hypotheses in complex, operationally representative environments: first, that unmanned tactical wheeled vehicles provide a force protection advantage by creating standoff distance to warfighters during ambushes or improvised explosive device attacks; and second, that these UGVs serve as force multipliers by enabling a single operator to control multiple unmanned assets. To assess whether current state-of-the-art autonomous vehicle technology was sufficiently capable to permit resupply missions to be executed with decreased risk and reduced manpower, and to assess the effect of UGVs on customary convoy tactics, the Marine Corps Warfighting Laboratory and the Joint Ground Robotics Enterprise sponsored Oshkosh Defense and the National Robotics Engineering Center to equip two standard Marine Corps cargo trucks for autonomous operation. This paper details the system architecture, hardware implementation, and software modules developed to meet the vehicle control, perception, and planner requirements compelled by this application. Additionally, the design of a custom human machine interface and an accompanying training program are described, as is the creation of a realistic convoy simulation environment for rapid system development. Finally, results are conveyed from a warfighter experiment in which the effectiveness of the training program for novice operators was assessed, and the impact of the UGVs on convoy operations was observed in a variety of scenarios via direct comparison to a fully manned convoy.

  5. Functional architecture of the retromer cargo-recognition complex

    Science.gov (United States)

    Hierro, Aitor; Rojas, Adriana L.; Rojas, Raul; Murthy, Namita; Effantin, Grégory; Kajava, Andrey V.; Steven, Alasdair C.; Bonifacino, Juan S.; Hurley, James H.

    2008-01-01

    The retromer complex 1, 2 is required for the sorting of acid hydrolases to lysosomes 3-7, transcytosis of the polymeric Ig receptor 8, Wnt gradient formation 9, 10, iron transporter recycling 11, and processing of the amyloid precursor protein 12. Human retromer consists of two smaller complexes, the cargo recognition Vps26:Vps29:Vps35 heterotrimer, and a membrane-targeting heterodimer or homodimer of SNX1 and/or SNX2 13. The crystal structure of a Vps29:Vps35 subcomplex shows how the metallophosphoesterase-fold subunit Vps29 14, 15 acts as a scaffold for the C-terminal half of Vps35. Vps35 forms a horseshoe-shaped right-handed α-helical solenoid whose concave face completely covers the metal-binding site of Vps29 and whose convex face exposes a series of hydrophobic interhelical grooves. Electron microscopy shows that the intact Vps26:Vps29:Vps35 complex is a stick-shaped, somewhat flexible, structure, ∼ 21 nm long. A hybrid structural model derived from crystal structures, electron microscopy, interaction studies, and bioinformatics shows that the α-solenoid fold extends the full length of Vps35, and that Vps26 is bound at the opposite end from Vps29. This extended structure presents multiple binding sites for the SNX complex and receptor cargo, and appears capable of flexing to conform to curved vesicular membranes. PMID:17891154

  6. Air Force Research Laboratory Technology Milestones 2007

    Science.gov (United States)

    2007-01-01

    Veterinary Sciences Warfighter/Weapons Systems Integration AF echnologies Information Directorate Mission Statement: The Information Directorate leads...Advanced Industrial Practices Advanced Inspection Technologies Advanced Metallics Air Mobile Systems Research Airbase Infrastructure Technologies...Air Mobility Command, and the C- 130 System Program Office-will help to raise awareness regarding these technologies. Tip tanks are fuel tanks

  7. Artificial Intelligence Assists Ultrasonic Inspection

    Science.gov (United States)

    Schaefer, Lloyd A.; Willenberg, James D.

    1992-01-01

    Subtle indications of flaws extracted from ultrasonic waveforms. Ultrasonic-inspection system uses artificial intelligence to help in identification of hidden flaws in electron-beam-welded castings. System involves application of flaw-classification logic to analysis of ultrasonic waveforms.

  8. FAA Fluorescent Penetrant Laboratory Inspections

    Energy Technology Data Exchange (ETDEWEB)

    WINDES,CONNOR L.; MOORE,DAVID G.

    2000-08-02

    The Federal Aviation Administration Airworthiness Assurance NDI Validation Center currently assesses the capability of various non-destructive inspection (NDI) methods used for analyzing aircraft components. The focus of one such exercise is to evaluate the sensitivity of fluorescent liquid penetrant inspection. A baseline procedure using the water-washable fluorescent penetrant method defines a foundation for comparing the brightness of low cycle fatigue cracks in titanium test panels. The analysis of deviations in the baseline procedure will determine an acceptable range of operation for the steps in the inspection process. The data also gives insight into the depth of each crack and which step(s) of the inspection process most affect penetrant sensitivities. A set of six low cycle fatigue cracks produced in 6.35-mm thick Ti-6Al-4V specimens was used to conduct the experiments to produce sensitivity data. The results will document the consistency of the crack readings and compare previous experiments to find the best parameters for water-washable penetrant.

  9. Maglev Launch: Ultra-low Cost, Ultra-high Volume Access to Space for Cargo and Humans

    Science.gov (United States)

    Powell, James; Maise, George; Rather, John

    2010-01-01

    Despite decades of efforts to reduce rocket launch costs, improvements are marginal. Launch cost to LEO for cargo is ~$10,000 per kg of payload, and to higher orbit and beyond much greater. Human access to the ISS costs $20 million for a single passenger. Unless launch costs are greatly reduced, large scale commercial use and human exploration of the solar system will not occur. A new approach for ultra low cost access to space-Maglev Launch-magnetically accelerates levitated spacecraft to orbital speeds, 8 km/sec or more, in evacuated tunnels on the surface, using Maglev technology like that operating in Japan for high speed passenger transport. The cost of electric energy to reach orbital speed is less than $1 per kilogram of payload. Two Maglev launch systems are described, the Gen-1System for unmanned cargo craft to orbit and Gen-2, for large-scale access of human to space. Magnetically levitated and propelled Gen-1 cargo craft accelerate in a 100 kilometer long evacuated tunnel, entering the atmosphere at the tunnel exit, which is located in high altitude terrain (~5000 meters) through an electrically powered ``MHD Window'' that prevents outside air from flowing into the tunnel. The Gen-1 cargo craft then coasts upwards to space where a small rocket burn, ~0.5 km/sec establishes, the final orbit. The Gen-1 reference design launches a 40 ton, 2 meter diameter spacecraft with 35 tons of payload. At 12 launches per day, a single Gen-1 facility could launch 150,000 tons annually. Using present costs for tunneling, superconductors, cryogenic equipment, materials, etc., the projected construction cost for the Gen-1 facility is 20 billion dollars. Amortization cost, plus Spacecraft and O&M costs, total $43 per kg of payload. For polar orbit launches, sites exist in Alaska, Russia, and China. For equatorial orbit launches, sites exist in the Andes and Africa. With funding, the Gen-1 system could operate by 2020 AD. The Gen-2 system requires more advanced technology

  10. Strong Interest In China’s Cargo Market——An interview with Jean-Peter Jansen, chairman of the Executive Board of Lufthansa Cargo AG.

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>Lufthansa Cargo AG ranks top among European airlines in the flights bound for China. It has 14 weekly flights for Hong Kong to transport 720 tons of cargo and mails, nine weekly services for Shanghai to carry 450 tons and four weekly flights for Beijing to handle 250 tons.The carrier is showing strong interest in the Chinese market, for 11 per cent of its sales in 2003, 2.16 billion euro came from China.

  11. A hopping mechanism for cargo transport by molecular motors in crowded microtubules

    CERN Document Server

    Goldman, Carla

    2010-01-01

    Most models designed to study the bidirectional movement of cargos as they are driven by molecular motors rely on the idea that motors of different polarities can be coordinated by external agents if arranged into a motor-cargo complex to perform the necessary work [gross04]. Although these models have provided us with important insights into these phenomena, there are still many unanswered questions regarding the mechanisms through which the movement of the complex takes place on crowded microtubules. For example (i) how does cargo-binding affect motor motility? and in connection with that - (ii) how does the presence of other motors (and also other cargos) on the microtubule affect the motility of the motor-cargo complex? We discuss these questions from a different perspective. The movement of a cargo is conceived here as a hopping process resulting from the transference of cargo between neighboring motors. In the light of this, we examine the conditions under which cargo might display bidirectional movemen...

  12. 33 CFR 126.29 - Supervision and control of dangerous cargo.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Supervision and control of... Supervision and control of dangerous cargo. (a) Authority. The Captain of the Port is authorized to require... cargo covered by this subchapter shall be undertaken and continued only under the immediate...

  13. Co-operative versus independent transport of different cargoes by Kinesin-1.

    Science.gov (United States)

    Hammond, Jennetta W; Griffin, Kelly; Jih, Gloria T; Stuckey, Jeanne; Verhey, Kristen J

    2008-05-01

    Kinesin motors drive the intracellular transport of multiple cargoes along microtubule tracks; yet, how kinesins discriminate among their many potential cargoes is unknown. We tested whether Kinesin-1 cargoes compete, co-operate or are transported independently of each other. We focused on Kinesin-1 cargoes that bind directly to the kinesin light chain (KLC) subunit, namely the c-Jun NH(2)-terminal kinase-interacting proteins (JIPs) 1 and 3, Kidins220/ARMS and PAT1. Overexpression of individual cargo proteins in differentiated CAD cells resulted in mislocalization of the endogenous protein but had no effect on localization of other cargo proteins to neurite tips. Thus, while transport of distinct cargoes is saturable, they do not compete with each other. Interestingly, we found that low expression of JIP1 or JIP3 enhanced the transport of the other JIP to neurite tips. Moreover, JIP1 and JIP3 require each other for transport. Co-operative transport is due to an interaction between JIP1 and JIP3 as well as distinct binding sites on the KLC tetratricopeptide repeat (TPR) bundle: the TPR groove binds to C-terminal residues of JIP1, whereas the TPR surface binds to internal residues in JIP3. Formation of a JIP1/JIP3/KLC complex is necessary for efficient JIP1 or JIP3 transport in neuronal cells. Thus, JIP scaffolding proteins are transported in a co-operative manner, despite the independent transport of other Kinesin-1 cargoes.

  14. 75 FR 59617 - Notification of Arrival in U.S. Ports; Certain Dangerous Cargoes

    Science.gov (United States)

    2010-09-28

    ... requirements. The 2005 definition of CDC residue only included residue quantities of bulk ammonium nitrate or ammonium nitrate fertilizer that remained onboard after the vessel discharges all saleable cargo; no other... until the removal of all bulk liquid and liquefied gas CDC cargoes, including residue quantities of...

  15. 46 CFR 308.551 - War risk insurance clearing agency agreement for cargo, Form MA-321.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false War risk insurance clearing agency agreement for cargo... EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Iv-General § 308.551 War risk insurance... American War Risk Agency or MARAD....

  16. 77 FR 35993 - Agency Information Collection Activities: Cargo Container and Road Vehicle Certification for...

    Science.gov (United States)

    2012-06-15

    ... affected agencies. This information collection was previously published in the Federal Register (77 FR... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Cargo Container and... Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act: Cargo Container...

  17. 46 CFR 153.981 - Leaving room in tank for cargo expansion.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Leaving room in tank for cargo expansion. 153.981 Section 153.981 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS... Transfer Procedures § 153.981 Leaving room in tank for cargo expansion. The person in charge of...

  18. 46 CFR 153.602 - Special requirements for cargoes reactive with water.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Special requirements for cargoes reactive with water. 153.602 Section 153.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK... and Equipment Special Requirements § 153.602 Special requirements for cargoes reactive with...

  19. 77 FR 19030 - Automated Commercial Environment Required for the Transmission of Advance Ocean and Rail Cargo...

    Science.gov (United States)

    2012-03-29

    .... 12-06] Automated Commercial Environment Required for the Transmission of Advance Ocean and Rail Cargo... Automated Commercial Environment (ACE) for the transmission of advance ocean and rail cargo information... controlled environment.\\3\\ M1 test participants were chosen based on the specific type of software...

  20. 78 FR 50134 - Altus Pharmaceuticals, Inc., Blackhawk Capital Group BDC, Inc., Cargo Connection Logistics...

    Science.gov (United States)

    2013-08-16

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Altus Pharmaceuticals, Inc., Blackhawk Capital Group BDC, Inc., Cargo Connection Logistics Holding... securities of Cargo Connection Logistics Holding, Inc. because it has not filed any periodic reports...

  1. CargoVibes: human response to vibration due to freight rail traffic

    NARCIS (Netherlands)

    Waddington, D.; Woodcock, J.; Smith, M.G.; Janssen, S.A.; Persson Waye, K.

    2015-01-01

    The aim of this paper is to present an overview of the research concerning human response to vibration conducted in the EU FP7 CargoVibes project. The European Union-funded project CargoVibes involved 10 partners from 8 nations and ran from April 2011 to April 2014. The project was concerned with ra

  2. Extensive cargo identification reveals distinct biological roles of the 12 importin pathways

    Science.gov (United States)

    Kimura, Makoto; Morinaka, Yuriko; Imai, Kenichiro; Kose, Shingo; Horton, Paul; Imamoto, Naoko

    2017-01-01

    Vast numbers of proteins are transported into and out of the nuclei by approximately 20 species of importin-β family nucleocytoplasmic transport receptors. However, the significance of the multiple parallel transport pathways that the receptors constitute is poorly understood because only limited numbers of cargo proteins have been reported. Here, we identified cargo proteins specific to the 12 species of human import receptors with a high-throughput method that employs stable isotope labeling with amino acids in cell culture, an in vitro reconstituted transport system, and quantitative mass spectrometry. The identified cargoes illuminated the manner of cargo allocation to the receptors. The redundancies of the receptors vary widely depending on the cargo protein. Cargoes of the same receptor are functionally related to one another, and the predominant protein groups in the cargo cohorts differ among the receptors. Thus, the receptors are linked to distinct biological processes by the nature of their cargoes. DOI: http://dx.doi.org/10.7554/eLife.21184.001 PMID:28117667

  3. 46 CFR 308.523 - Application for revision of Open Cargo Policy, Form MA-303.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Application for revision of Open Cargo Policy, Form MA-303. 308.523 Section 308.523 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY... Application for revision of Open Cargo Policy, Form MA-303. An application for the revision of an Open...

  4. 46 CFR 308.548 - Standard form of underwriting agency agreement for cargo, Form MA-318.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standard form of underwriting agency agreement for cargo, Form MA-318. 308.548 Section 308.548 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... underwriting agency agreement for cargo, Form MA-318. This form, which may be obtained from the American...

  5. 46 CFR 308.545 - Facultative cargo policy, Form MA-316.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Facultative cargo policy, Form MA-316. 308.545 Section 308.545 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK... policy, Form MA-316. The standard form of War Risk Facultative Cargo Policy, Form MA-316, may be...

  6. 46 CFR 308.524 - Application for cancellation of Open Cargo Policy, Form MA-304.

    Science.gov (United States)

    2010-10-01

    ... MA-304. 308.524 Section 308.524 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... § 308.524 Application for cancellation of Open Cargo Policy, Form MA-304. The standard form of application for cancellation of an Open Cargo Policy Form MA-304 may be obtained from the American War...

  7. 46 CFR 154.1210 - Hold space, void space, cofferdam, and spaces containing cargo piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Hold space, void space, cofferdam, and spaces containing... Design, Construction and Equipment Cargo Area: Mechanical Ventilation System § 154.1210 Hold space, void space, cofferdam, and spaces containing cargo piping. (a) Each hold space, void space, cofferdam,...

  8. 46 CFR 38.10-10 - Cargo piping-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo piping-TB/ALL. 38.10-10 Section 38.10-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS LIQUEFIED FLAMMABLE GASES Piping, Valves, Fittings, and Accessory Equipment § 38.10-10 Cargo piping—TB/ALL. (a) The piping shall be designed for...

  9. 76 FR 14643 - Hazardous Materials: Safety Requirements for External Product Piping on Cargo Tanks Transporting...

    Science.gov (United States)

    2011-03-17

    ...: Safety Requirements for External Product Piping on Cargo Tanks Transporting Flammable Liquids AGENCY... external product piping (wetlines) on a cargo tank motor vehicle (CTMV) unless the CTMV is equipped with... National Tank Truck Carriers, Inc., and the Tank Truck Manufacturers Association requesting an extension...

  10. 77 FR 21579 - Agency Information Collection Activities: Transfer of Cargo to a Container Station

    Science.gov (United States)

    2012-04-10

    ... a Container Station AGENCY: U.S. Customs and Border Protection, Department of Homeland Security... and approval in accordance with the Paperwork Reduction Act: Transfer of Cargo to a Container Station... forms of information. Title: Transfer of Cargo to a Container Station. OMB Number: 1651-0096....

  11. 29 CFR Appendix III to Part 1918 - The Mechanics of Conventional Cargo Gear (Non-mandatory)

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false The Mechanics of Conventional Cargo Gear (Non-mandatory.... 1918, App. III Appendix III to Part 1918—The Mechanics of Conventional Cargo Gear (Non-mandatory) Note: This appendix is non-mandatory and provides an explanation of the mechanics in the correct spotting...

  12. Automated Ply Inspection (API) for AFP Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Automated Ply Inspection (API) system autonomously inspects layups created by high speed automated fiber placement (AFP) machines. API comprises a high accuracy...

  13. Advanced robotics for inspection and maintenance applications

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, B. [Intech Inc., Chattanooga, Tennessee (United States)

    2008-07-01

    The BOP inspection market provides unique and challenging environments for inspection. Intech has developed a flexible manipulator platform that supports these needs, namely accuracy and environmental hazards in a cost effective package. (author)

  14. Piping inspection carriage having axially displaceable sensor

    Science.gov (United States)

    Zollinger, William T.; Treanor, Richard C.

    1994-01-01

    A pipe inspection instrument carriage for use with a pipe crawler for performing internal inspections of piping surfaces. The carriage has a front leg assembly, a rear leg assembly and a central support connecting the two assemblies and for mounting an instrument arm having inspection instruments. The instrument arm has a y-arm mounted distally thereon for axially aligning the inspection instrumentation and a mounting block, a linear actuator and axial movement arm for extending the inspection instruments radially outward to operably position the inspection instruments on the piping interior. Also, the carriage has a rotation motor and gear assembly for rotating the central support and the front leg assembly with respect to the rear leg assembly so that the inspection instruments azimuthally scan the piping interior. The instrument carriage allows performance of all piping inspection operations with a minimum of moving parts, thus decreasing the likelihood of performance failure.

  15. Allegheny County Housing and Community Environment Inspections

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Residential housing inspections and inspections in response to complaints for community environment problems, such as open vacant structures, vacant lots with...

  16. Automated Infrared Inspection Of Jet Engine Turbine Blades

    Science.gov (United States)

    Bantel, T.; Bowman, D.; Halase, J.; Kenue, S.; Krisher, R.; Sippel, T.

    1986-03-01

    The detection of blocked surface cooling holes in hollow jet engine turbine blades and vanes during either manufacture or overhaul can be crucial to the integrity and longevity of the parts when in service. A fully automated infrared inspection system is being established under a tri-service's Manufacturing Technology (ManTech) contract administered by the Air Force to inspect these surface cooling holes for blockages. The method consists of viewing the surface holes of the blade with a scanning infrared radiometer when heated air is flushed through the blade. As the airfoil heats up, the resultant infrared images are written directly into computer memory where image analysis is performed. The computer then makes a determination of whether or not the holes are open from the inner plenum to the exterior surface and ultimately makes an accept/reject decision based on previously programmed criteria. A semiautomatic version has already been implemented and is more cost effective and more reliable than the previous manual inspection methods.

  17. VAMP4 Is an Essential Cargo Molecule for Activity-Dependent Bulk Endocytosis.

    Science.gov (United States)

    Nicholson-Fish, Jessica C; Kokotos, Alexandros C; Gillingwater, Thomas H; Smillie, Karen J; Cousin, Michael A

    2015-12-02

    The accurate formation of synaptic vesicles (SVs) and incorporation of their protein cargo during endocytosis is critical for the maintenance of neurotransmission. During intense neuronal activity, a transient and acute accumulation of SV cargo occurs at the plasma membrane. Activity-dependent bulk endocytosis (ADBE) is the dominant SV endocytosis mode under these conditions; however, it is currently unknown how ADBE mediates cargo retrieval. We examined the retrieval of different SV cargo molecules during intense stimulation using a series of genetically encoded pH-sensitive reporters in neuronal cultures. The retrieval of only one reporter, VAMP4-pHluorin, was perturbed by inhibiting ADBE. This selective recovery was confirmed by the enrichment of endogenous VAMP4 in purified bulk endosomes formed by ADBE. VAMP4 was also essential for ADBE, with a cytoplasmic di-leucine motif being critical for this role. Therefore, VAMP4 is the first identified ADBE cargo and is essential for this endocytosis mode to proceed.

  18. A novel architecture for cargos location and safety in networked RFID

    Institute of Scientific and Technical Information of China (English)

    HUANG Dong-li; YUAN Zheng-wu; Byeong-Seob You; Sook-Kyung Cho; Hae-Young Bae

    2007-01-01

    Using Networked RFID equipped in warehouse or supermarket distribution, Enterprise information system (EIS) can gather and deal with cargos information. Nevertheless, when cargos are in traffic, the Networked RFID can't monitor the cargos any more as the products tagged aren't within range of a reader. This paper proposes a solution framework which combines Networked RFID and GPS tracking, and then equip with this system in container to make the cargos monitored even if the cargos are in traffic. This solution can solve the accurate consignments, position tracking and advanced theft happening through drilling holes in container. In addition, customhouse and checkpoint can get an electronic shipment manifest rapidly and safely when a vehicle gets through a checkpoint.

  19. Structural Basis of Cargo Recognition by Unconventional Myosins in Cellular Trafficking.

    Science.gov (United States)

    Li, Jianchao; Lu, Qing; Zhang, Mingjie

    2016-08-01

    Unconventional myosins are a superfamily of actin-based molecular motors playing diverse roles including cellular trafficking, mechanical supports, force sensing and transmission, etc. The variable neck and tail domains of unconventional myosins function to bind to specific cargoes including proteins and lipid vesicles and thus are largely responsible for the diverse cellular functions of myosins in vivo. In addition, the tail regions, together with their cognate cargoes, can regulate activities of the motor heads. This review outlines the advances made in recent years on cargo recognition and cargo binding-induced regulation of the activity of several unconventional myosins including myosin-I, V, VI and X in cellular trafficking. We approach this topic by describing a series of high-resolution structures of the neck and tail domains of these unconventional myosins either alone or in complex with their specific cargoes, and by discussing potential implications of these structural studies on cellular trafficking of these myosin motors.

  20. Experimental Stress Analysis at Railway Inspection Pit

    Directory of Open Access Journals (Sweden)

    Nicuşor Laurentiu Zaharia

    2008-10-01

    Full Text Available Railway inspection pits are used in railway halls. The purpose of inspection pits is to allow the working under the vehicle. Inspection pits can be found in locomotive depots, factories etc. The new design for a inspection pit in a railway hall involve tests in purpose of homologations the railway infrastructure. Before the homologation committee meeting, tests are made; after the test, a testing report is made which it will be part at homologation documents.

  1. Northwest passage: Trade route for large air cushion vehicles

    Science.gov (United States)

    Anderson, J. L.

    1973-01-01

    A conceptual vehicle and powerplant (10,000-ton) nuclear-powered air-cushion vehicle (ACV) that could open the Northwest Passage and other Arctic passages to commercial traffic is identified. The report contains a description of the conceptual vehicle, including the powerplant and operations, an assessment of technical feasibility, estimates of capital and operating costs, and identification of eligible cargo and markets. A comparison of the nuclear ACV freighter with nuclear container ships shows that for containerized or roll-on/roll-off cargo the ACV would provide greatly reduced transit time between North Atlantic and North Pacific ports at a competitive cost.

  2. 78 FR 63877 - Approval and Promulgation of Air Quality Implementation Plans; Delaware; Infrastructure...

    Science.gov (United States)

    2013-10-25

    ... human health or environmental effects, using practicable and legally permissible methods, under... Environmental protection, Air pollution control, Incorporation by reference, Nitrogen dioxide, Reporting and... for public inspection during normal business hours at the Air Protection Division, U.S....

  3. Modelling in Optimal Inspection and Repair

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Rackwitz, R.; Faber, M.H.;

    1991-01-01

    A model for reliability based optimal inspection and repair strategies is described. The total expected costs in the lifetime is minimized with the number of inspections, the inspection times and efforts, the repair crack size limit and a design parameter as optimization variables. The equivalenc...

  4. Explosion impacts during transport of hazardous cargo: GIS-based characterization of overpressure impacts and delineation of flammable zones for ammonia.

    Science.gov (United States)

    Inanloo, Bahareh; Tansel, Berrin

    2015-06-01

    The aim of this research was to investigate accidental releases of ammonia followed by an en-route incident in an attempt to further predict the consequences of hazardous cargo accidents. The air dispersion model Areal Locations of Hazardous Atmospheres (ALOHA) was employed to track the probable outcomes of a hazardous material release of a tanker truck under different explosion scenarios. The significance of identification of the flammable zones was taken into consideration; in case the flammable vapor causes an explosion. The impacted areas and the severity of the probable destructions were evaluated for an explosion by considering the overpressure waves. ALOHA in conjunction with ArcGIS was used to delineate the flammable and overpressure impact zones for different scenarios. Based on the results, flammable fumes were formed in oval shapes having a chief axis along the wind direction at the time of release. The expansions of the impact areas under the overpressure value which can lead to property damage for 2 and 20 tons releases, under very stable and unstable atmospheric conditions were estimated to be around 1708, 1206; 3742, 3527 feet, respectively, toward the wind direction. A sensitivity analysis was done to assess the significance of wind speed on the impact zones. The insight provided by this study can be utilized by decision makers in transportation of hazardous materials as a guide for possible rerouting, rescheduling, or limiting the quantity of hazardous cargo to reduce the possible impacts after hazardous cargo accidents during transport.

  5. 46 CFR 38.05-3 - Design and construction of pressure vessel type cargo tanks-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Design and construction of pressure vessel type cargo... LIQUEFIED FLAMMABLE GASES Design and Installation § 38.05-3 Design and construction of pressure vessel type cargo tanks—TB/ALL. (a) Cargo tanks of pressure vessel configuration (e.g. cylindrical, spherical,...

  6. 49 CFR 175.702 - Separation distance requirements for packages containing Class 7 (radioactive) materials in cargo...

    Science.gov (United States)

    2010-10-01

    ... containing Class 7 (radioactive) materials in cargo aircraft. 175.702 Section 175.702 Transportation Other... (radioactive) materials in cargo aircraft. (a) No person may carry in a cargo aircraft any package required by... separation distance between the surfaces of the radioactive materials packages, overpacks or...

  7. 78 FR 21037 - Special Conditions: Airbus Model A330-200 Airplanes; Bulk Cargo Lower Deck Crew Rest Compartments

    Science.gov (United States)

    2013-04-09

    ... Cargo Lower Deck Crew Rest Compartments AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... unusual design feature associated with the installation of bulk cargo lower deck crew rest compartments... supplemental type certificate to install a bulk cargo lower deck crew rest compartment in the Airbus Model...

  8. 49 CFR 176.84 - Other requirements for stowage and segregation for cargo vessels and passenger vessels.

    Science.gov (United States)

    2010-10-01

    ... May be stowed in portable magazine or metal locker. 16 No other cargo may be stowed in the same hold... solids. 101 Stow “separated from” iron oxide. 102 Stow “separated from” all odor absorbing cargoes. 103... must be steel. 15E On deck, cargo transport unit must be leakproof. 17E On deck stowage is...

  9. ATHLETE: A Cargo-Handling Vehicle for Solar System Exploration

    Science.gov (United States)

    Wilcox, Brian H.

    2011-01-01

    As part of the NASA Exploration Technology Development Program, the Jet Propulsion Laboratory is developing a vehicle called ATHLETE: the All-Terrain Hex-Limbed Extra-Terrestrial Explorer. Each vehicle is based on six wheels at the ends of six multi-degree-of-freedom limbs. Because each limb has enough degrees of freedom for use as a general-purpose leg, the wheels can be locked and used as feet to walk out of excessively soft or other extreme terrain. Since the vehicle has this alternative mode of traversing through or at least out of extreme terrain, the wheels and wheel actuators can be sized for nominal terrain. There are substantial mass savings in the wheel and wheel actuators associated with designing for nominal instead of extreme terrain. These mass savings are comparable-to or larger-than the extra mass associated with the articulated limbs. As a result, the entire mobility system, including wheels and limbs, can be about 25% lighter than a conventional mobility chassis. A side benefit of this approach is that each limb has sufficient degrees-of-freedom to use as a general-purpose manipulator (hence the name "limb" instead of "leg"). Our prototype ATHLETE vehicles have quick-disconnect tool adapters on the limbs that allow tools to be drawn out of a "tool belt" and maneuvered by the limb. A power-take-off from the wheel actuates the tools, so that they can take advantage of the 1+ horsepower motor in each wheel to enable drilling, gripping or other power-tool functions. Architectural studies have indicated that one useful role for ATHLETE in planetary (moon or Mars) exploration is to "walk" cargo off the payload deck of a lander and transport it across the surface. Recent architectural approaches are focused on the concept that the lander descent stage will use liquid hydrogen as a propellant. This is the highest performance chemical fuel, but it requires very large tanks. A natural geometry for the lander is to have a single throttleable rocket engine on

  10. 46 CFR 154.1852 - Air breathing equipment.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Air breathing equipment. 154.1852 Section 154.1852... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Operations § 154.1852 Air breathing equipment. (a) The master shall ensure that a licensed officer inspects the compressed air...

  11. Pipe inspection using the pipe crawler. Innovative technology summary report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The US Department of Energy (DOE) continually seeks safer and more cost-effective remediation technologies for use in the decontamination and decommissioning (D and D) of nuclear facilities. In several of the buildings at the Fernald Site, there is piping that was used to transport process materials. As the demolition of these buildings occur, disposal of this piping has become a costly issue. Currently, all process piping is cut into ten-foot or less sections, the ends of the piping are wrapped and taped to prevent the release of any potential contaminants into the air, and the piping is placed in roll off boxes for eventual repackaging and shipment to the Nevada Test Site (NTS) for disposal. Alternatives that allow for the onsite disposal of process piping are greatly desired due to the potential for dramatic savings in current offsite disposal costs. No means is currently employed to allow for the adequate inspection of the interior of piping, and consequently, process piping has been assumed to be internally contaminated and thus routinely disposed of at NTS. The BTX-II system incorporates a high-resolution micro color camera with lightheads, cabling, a monitor, and a video recorder. The complete probe is capable of inspecting pipes with an internal diameter (ID) as small as 1.4 inches. By using readily interchangeable lightheads, the same system is capable of inspecting piping up to 24 inches in ID. The original development of the BTX system was for inspection of boiler tubes and small diameter pipes for build-up, pitting, and corrosion. However, the system is well suited for inspecting the interior of most types of piping and other small, confined areas. The report describes the technology, its performance, uses, cost, regulatory and policy issues, and lessons learned.

  12. Generative inspection process planner for integrated production

    Energy Technology Data Exchange (ETDEWEB)

    Brown, C.W. (Allied-Signal Aerospace Co., Kansas City, MO (USA). Kansas City Div.); Gyorog, D.A. (Kansas Univ., Lawrence, KS (USA). Dept. of Mechanical Engineering)

    1990-04-01

    This work describes the design prototype development of a generative process planning system for dimensional inspection. The system, IPPEX (Inspection Process Planning EXpert), is a rule-based expert system for integrated production. Using as advanced product modeler, relational databases, and artificial intelligence techniques, IPPEX generates the process plan and part program for the dimensional inspection of products using CMMs. Through an application interface, the IPPEX system software accesses product definition from the product modeler. The modeler is a solid geometric modeler coupled with a dimension and tolerance modeler. Resource data regarding the machines, probes, and fixtures are queried from databases. IPPEX represents inspection process knowledge as production rules and incorporates an embedded inference engine to perform decision making. The IPPEX system, its functional architecture, system architecture, system approach, product modeling environment, inspection features, inspection knowledge, hierarchical planning strategy, user interface formats, and other fundamental issues related to inspection planning and part programming for CMMs are described. 27 refs., 16 figs., 4 tabs.

  13. Charting the Course for a New Air Force Inspection System

    Science.gov (United States)

    2013-01-01

    Assessment Program LOSA Line-Oriented Safety Auditing M-ASAP Military Aviation Safety Action Program M-FOQA Military Flight Operations Quality Assurance...implement voluntary programs as part of their own internal evaluation systems. The Line-Oriented Safety Auditing ( LOSA ) program is an example of...such a program. Under LOSA , an airline hires a third-party observer to monitor various aspects of its operations. For example, the third party might

  14. Advanced analysis of the transverse bulkhead of the a general cargo ship

    Science.gov (United States)

    Axinte, T.; Nutu, C.; Stanca, C.; Cupsa, O.; Carp, A.

    2016-08-01

    The paper presents the main strength factors stressing the transverse bulkhead of a cargo ship. The transverse bulkhead is one of the main components of the hull for a general cargo vessel. There are presented the role and the importance of the general cargo vessel's type using an original drawing made in NX 8.0 Software from Siemens. Further on, we are presented the importance of the transverse bulkhead of the general cargo ship's hull. Next there are analysed the formability of the transverse bulkhead's material and then we are determining the shear, normal and von Mises stresses in the traverse bulkhead, using the finite element method. Once the stresses are computed, there are also determined the fatigue life, strength safety factor and fatigue safety factor. The analysis of the transverse bulkhead is important for the safety of the general cargo vessel type because if this component of the ship does not resist to the various stresses and high deformations during bad storms on the sea or if the cargo is stored inappropriately, deformations or even breakage of the transverse bulkhead can occur, thus causing damages of the cargo ship, especially under heavy storm.

  15. Mechanisms for exporting large-sized cargoes from the endoplasmic reticulum.

    Science.gov (United States)

    Saito, Kota; Katada, Toshiaki

    2015-10-01

    Cargo proteins exported from the endoplasmic reticulum to the Golgi apparatus are typically transported in coat protein complex II (COPII)-coated vesicles of 60-90 nm diameter. Several cargo molecules including collagens and chylomicrons form structures that are too large to be accommodated by these vesicles, but their secretion still requires COPII proteins. Here, we first review recent progress on large cargo secretions derived especially from animal models and human diseases, which indicate the importance of COPII proteins. We then discuss the recent isolation of specialized factors that modulate the process of COPII-dependent cargo formation to facilitate the exit of large-sized cargoes from the endoplasmic reticulum. Based on these findings, we propose a model that describes the importance of the GTPase cycle for secretion of oversized cargoes. Next, we summarize reports that describe the structures of COPII proteins and how these results provide insight into the mechanism of assembly of the large cargo carriers. Finally, we discuss what issues remain to be solved in the future.

  16. A propagating ATPase gradient drives transport of surface-confined cellular cargo.

    Science.gov (United States)

    Vecchiarelli, Anthony G; Neuman, Keir C; Mizuuchi, Kiyoshi

    2014-04-01

    The faithful segregation of duplicated genetic material into daughter cells is critical to all organisms. In many bacteria, the segregation of chromosomes involves transport of "centromere-like" loci over the main body of the chromosome, the nucleoid, mediated by a two-protein partition system: a nonspecific DNA-binding ATPase, ParA, and an ATPase stimulator, ParB, which binds to the centromere-like loci. These systems have previously been proposed to function through a filament-based mechanism, analogous to actin- or microtubule-based movement. Here, we reconstituted the F-plasmid partition system using a DNA-carpeted flow cell as an artificial nucleoid surface and magnetic beads coated with plasmid partition complexes as surface-confined cargo. This minimal system recapitulated directed cargo motion driven by a surface ATPase gradient that propagated with the cargo. The dynamics are consistent with a diffusion-ratchet model, whereby the cargo dynamically establishes, and interacts with, a concentration gradient of the ATPase. A chemophoresis force ensues as the cargo perpetually chases the ATPase gradient, allowing the cargo to essentially "surf" the nucleoid on a continuously traveling wave of the ATPase. Demonstration of this non-filament-based motility mechanism in a biological context establishes a distinct class of motor system used for the transport and positioning of large cellular cargo.

  17. Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery.

    Science.gov (United States)

    Qian, Ziqing; LaRochelle, Jonathan R; Jiang, Bisheng; Lian, Wenlong; Hard, Ryan L; Selner, Nicholas G; Luechapanichkul, Rinrada; Barrios, Amy M; Pei, Dehua

    2014-06-24

    Cyclic heptapeptide cyclo(FΦRRRRQ) (cFΦR4, where Φ is l-2-naphthylalanine) was recently found to be efficiently internalized by mammalian cells. In this study, its mechanism of internalization was investigated by perturbing various endocytic events through the introduction of pharmacologic agents and genetic mutations. The results show that cFΦR4 binds directly to membrane phospholipids, is internalized into human cancer cells through endocytosis, and escapes from early endosomes into the cytoplasm. Its cargo capacity was examined with a wide variety of molecules, including small-molecule dyes, linear and cyclic peptides of various charged states, and proteins. Depending on the nature of the cargos, they may be delivered by endocyclic (insertion of cargo into the cFΦR4 ring), exocyclic (attachment of cargo to the Gln side chain), or bicyclic approaches (fusion of cFΦR4 and cyclic cargo rings). The overall delivery efficiency (i.e., delivery of cargo into the cytoplasm and nucleus) of cFΦR4 was 4-12-fold higher than those of nonaarginine, HIV Tat-derived peptide, or penetratin. The higher delivery efficiency, coupled with superior serum stability, minimal toxicity, and synthetic accessibility, renders cFΦR4 a useful transporter for intracellular cargo delivery and a suitable system for investigating the mechanism of endosomal escape.

  18. Systems Analysis and Structural Design of an Unpressurized Cargo Delivery Vehicle

    Science.gov (United States)

    Wu, K. Chauncey; Cruz, Jonathan N.; Antol, Jeffrey; Sasamoto, Washito A.

    2007-01-01

    The International Space Station will require a continuous supply of replacement parts for ongoing maintenance and repair after the planned retirement of the Space Shuttle in 2010. These parts are existing line-replaceable items collectively called Orbital Replacement Units, and include heavy and oversized items such as Control Moment Gyroscopes and stowed radiator arrays originally intended for delivery aboard the Space Shuttle. Current resupply spacecraft have limited to no capability to deliver these external logistics. In support of NASA's Exploration Systems Architecture Study, a team at Langley Research Center designed an Unpressurized Cargo Delivery Vehicle to deliver bulk cargo to the Space Station. The Unpressurized Cargo Delivery Vehicle was required to deliver at least 13,200 lbs of cargo mounted on at least 18 Flight Releasable Attachment Mechanisms. The Crew Launch Vehicle design recommended in the Exploration Systems Architecture Study would be used to launch one annual resupply flight to the International Space Station. The baseline vehicle design developed here has a cargo capacity of 16,000 lbs mounted on up to 20 Flight Releasable Attachment Mechanisms. Major vehicle components are a 5.5m-diameter cargo module containing two detachable cargo pallets with the payload, a Service Module to provide propulsion and power, and an aerodynamic nose cone. To reduce cost and risk, the Service Module is identical to the one used for the Crew Exploration Vehicle design.

  19. ATMOSPHERE PROTECTION IN CASE OF EMERGENCY DURING TRANSPORTATION OF DANGEROUS CARGO

    Directory of Open Access Journals (Sweden)

    O. V. Berlov

    2016-02-01

    Full Text Available Purpose. The paper highlights the development of numerical models for prediction of atmospheric pollution in case of burning of the solid rocket propellant in a railway car, situated near the building on railway territory. These models can be used in predicting the effectiveness of neutralization upon the atmosphere protection for this type of accidents. Methodology.To solve this problem the numerical models based on the use of Navier-Stokes equations, to determine the velocity field of the wind flow near cars and buildings, and contaminants-transfer equations in the atmosphere were developed. For the numerical integration of pollutant transport equation was used implicit «change – triangle» difference scheme. When constructing a difference scheme physical and geometric cleavage of the transfer equation is carried out in four steps. Unknown value of pollutant concentration at each step of cleavage is determined by the explicit scheme – the method of «point-to-point computation». For the numerical integration of the Navier-Stokes equations are used implicit difference schemes. When carrying out computing experiment also takes into account: the velocity profile of wind flow; interaction between the building and the wind flow and flame jet of solid rocket propellant; the presence of a railroad car; inside which there is a source of pollution; instability of pollutant emissions. On the basis of constructed numerical models was performed the computer experiment for assessing the level of air pollution at dangerous cargo rail transportation in case of emergency at railway territory.The application calculations for the timely combustion products neutralization of solid rocket propellant were carried out. Findings. The numerical models that let promptly calculate air contamination in case of emergency during solid rocket propellant transportation, as well as calculate the rational parameters of pollutant neutralization process were developed by

  20. Developing the information management system for safeguards national inspection

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. J.; Jeon, I.; Park, W. S.; Min, K. S. [KAERI, Taejon (Korea, Republic of)

    2003-10-01

    The inspection information management system for safeguards national inspection is aimed to do the national safeguards inspection with efficiency, and to decrease the inspector's load to write inspection report by systematizing the inspection jobs and sharing the inspection data. National safeguards inspection is consisted two large jobs. The first is the national safeguards supporting job of managing to support the national inspection mission. The other is the writing a national inspection report after completing the national inspection. Before the developing of inspection information management system, the official tools(spread sheet, word processor) are usually used. But there is problem to share the data, to produce the statistics data. To solve the these problem, we developed the inspection information management system that process the job from initial to final inspection work, and opened user education. This paper explain the procedure of developing the inspection information management system for safeguards national inspection.

  1. Redox-regulated cargo binding and release by the peroxisomal targeting signal receptor, Pex5.

    Science.gov (United States)

    Ma, Changle; Hagstrom, Danielle; Polley, Soumi Guha; Subramani, Suresh

    2013-09-20

    In its role as a mobile receptor for peroxisomal matrix cargo containing a peroxisomal targeting signal called PTS1, the protein Pex5 shuttles between the cytosol and the peroxisome lumen. Pex5 binds PTS1 proteins in the cytosol via its C-terminal tetratricopeptide domains and delivers them to the peroxisome lumen, where the receptor·cargo complex dissociates. The cargo-free receptor is exported to the cytosol for another round of import. How cargo release and receptor recycling are regulated is poorly understood. We found that Pex5 functions as a dimer/oligomer and that its protein interactions with itself (homo-oligomeric) and with Pex8 (hetero-oligomeric) control the binding and release of cargo proteins. These interactions are controlled by a redox-sensitive amino acid, cysteine 10 of Pex5, which is essential for the formation of disulfide bond-linked Pex5 forms, for high affinity cargo binding, and for receptor recycling. Disulfide bond-linked Pex5 showed the highest affinity for PTS1 cargo. Upon reduction of the disulfide bond by dithiothreitol, Pex5 transitioned to a noncovalent dimer, concomitant with the partial release of PTS1 cargo. Additionally, dissipation of the redox balance between the cytosol and the peroxisome lumen caused an import defect. A hetero-oligomeric interaction between the N-terminal domain (amino acids 1-110) of Pex5 and a conserved motif at the C terminus of Pex8 further facilitates cargo release, but only under reducing conditions. This interaction is also important for the release of PTS1 proteins. We suggest a redox-regulated model for Pex5 function during the peroxisomal matrix protein import cycle.

  2. Air Cargo Development in the Regional Airports of the Baltic Sea Region Through Road Feeder Services

    Directory of Open Access Journals (Sweden)

    Beifert Anatoli

    2015-06-01

    Full Text Available As issued in the Competition Policy Brief on the new state aid rules for a competitive aviation industry by the Competition Directorate-General of the European Commission in February 20141, it will be more difficult for unprofitable airports, to obtain financial public subsidies on EU, national or regional level. Although the positive impact of small airports on the regional development and general accessibility was mentioned, still the operating aid to the airports shall be cut out over a maximum of 10 years. It has been further stated that the vast majority of small and regional airports experience problems to cover their running operative costs, as a result from an intensive market competition and overlapping of airports’ catchment areas preventing even some promising airports from growth. Public subsidies are mostly used by the airport management for infrastructural investments, to cover operating losses or to attract price-sensitive airlines. Herewith, among other things, the EU Commission is pointing out at the lack of cooperation structures and network strategies among the regional airports and at rather isolated and individual approach during elaboration of the airport development scenarios. However, the Competition Policy Brief permits public aid to regional airports, among other things if there is sufficient transports need to establish transition periods for small airports; the need for more flexibility of the regional airports in the remote areas has been underlined. The EU Commission is expecting herewith not to close the regional airports, but to stimulate them to operate on cost efficient and profitable basis, and that only the most inefficient airports will be closed.

  3. Aviation Security: Background and Policy Options for Screening and Securing Air Cargo

    Science.gov (United States)

    2008-02-25

    Available at [http://www.ntsb.gov]. 26 See 49 CFR §1544.202. California. His only luggage was a guitar case that concealed hammers, mallets, a knife, and a...Nonetheless, commercial products using millimeter wave imaging are currently available for application in standoff scanning of a wide variety of objects...identifier technology in airport access control systems; a list of products and vendors meeting these specifications; and specific procedures for

  4. Computational defect review for actinic mask inspections

    Science.gov (United States)

    Morgan, Paul; Rost, Daniel; Price, Daniel; Corcoran, Noel; Satake, Masaki; Hu, Peter; Peng, Danping; Yonenaga, Dean; Tolani, Vikram

    2013-04-01

    As optical lithography continues to extend into low-k1 regime, resolution of mask patterns continues to diminish. The limitation of 1.35 NA posed by water-based lithography has led to the application of various resolution enhancement techniques (RET), for example, use of strong phase-shifting masks, aggressive OPC and sub-resolution assist features, customized illuminators, etc. The adoption of these RET techniques combined with the requirements to detect even smaller defects on masks due to increasing MEEF, poses considerable challenges for a mask inspection engineer. Inspecting masks under their actinic-aerial image conditions would detect defects that are more likely to print under those exposure conditions. However, this also makes reviewing such defects in their low-contrast aerial images very challenging. On the other hand, inspecting masks under higher resolution inspection optics would allow for better viewing of defects post-inspection. However, such inspections generally would also detect many more defects, including printable and nuisance, thereby making it difficult to judge which are of real concern for printability on wafer. Often, an inspection engineer may choose to use Aerial and/or high resolution inspection modes depending on where in the process flow the mask is and the specific device-layer characteristics of the mask. Hence, a comprehensive approach is needed in handling defects both post-aerial and post-high resolution inspections. This analysis system is designed for the Applied Materials Aera™ mask inspection platform, all data reported was collected using the Aera.

  5. Restaurant inspection frequency and food safety compliance.

    Science.gov (United States)

    Newbold, K Bruce; McKeary, Marie; Hart, Robert; Hall, Robert

    2008-11-01

    Although food premises are regularly inspected, little information is available on the effect of inspections on compliance records, particularly with respect to the impact of the frequency of inspection on compliance. The following presents the outcome of a study designed to assess the impact of increased inspection frequency on compliance measures in Hamilton, Ontario, in the absence of any other changes to food handler/safety programs or legislation. High-risk food inspection premises were randomly assigned three, four, or five inspections per year. Results indicate that no statistical difference existed in outcome measures based on frequency of inspection. When premises were grouped based on the average time between inspections, premises with greater time between inspections scored better compliance measures relative to premises that were inspected more frequently. The study was also unique for the level of consultation and collaboration sought from the public health inspectors (PHIs) assigned to the Food Safety Program. Their knowledge and experience with respect to the critical variables associated with compliance were a complementary component to the literature review conducted by the research team.

  6. ANNUAL RADIOACTIVE WASTE TANK INSPECTION PROGRAM - 2011

    Energy Technology Data Exchange (ETDEWEB)

    West, B.; Waltz, R.

    2012-06-21

    Aqueous radioactive wastes from Savannah River Site (SRS) separations and vitrification processes are contained in large underground carbon steel tanks. Inspections made during 2011 to evaluate these vessels and other waste handling facilities along with evaluations based on data from previous inspections are the subject of this report. The 2011 inspection program revealed that the structural integrity and waste confinement capability of the Savannah River Site waste tanks were maintained. All inspections scheduled per SRR-LWE-2011-00026, HLW Tank Farm Inspection Plan for 2011, were completed. Ultrasonic measurements (UT) performed in 2011 met the requirements of C-ESR-G-00006, In-Service Inspection Program for High Level Waste Tanks, Rev. 3, and WSRC-TR-2002-00061, Rev.6. UT inspections were performed on Tanks 25, 26 and 34 and the findings are documented in SRNL-STI-2011-00495, Tank Inspection NDE Results for Fiscal Year 2011, Waste Tanks 25, 26, 34 and 41. A total of 5813 photographs were made and 835 visual and video inspections were performed during 2011. A potential leaksite was discovered at Tank 4 during routine annual inspections performed in 2011. The new crack, which is above the allowable fill level, resulted in no release to the environment or tank annulus. The location of the crack is documented in C-ESR-G-00003, SRS High Level Waste Tank Leaksite Information, Rev.6.

  7. Steam generator tube inspection in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Fukui, Shigetaka [Japan Power Engineering and Inspection Corp., Tokyo (Japan)

    1997-02-01

    Steam generator tube inspection was first carried out in 1971 at Mihama Unit-1 that is first PWR plant in Japan, when the plant was brought into the first annual inspection. At that time, inspection was made on sampling basis, and only bobbin coil probe was used. After experiencing various kinds of tube degradations, inspection method was changed from sampling to all number of tubes, and various kinds of probes were used to get higher detectability of flaw. At present, it is required that all the tubes shall be inspected in their full length at each annual inspection using standard bobbin coil probe, and some special probes for certain plants that have susceptibility of occurrence of flaw. Sleeve repaired portion is included in this inspection. As a result of analyses of eddy current testing data, all indications that have been evaluated to be 20% wall thickness or deeper shall be repaired by either plugging or sleeving, where flaw morphology is to be a wastage or wear. Other types of flaw such as IGA/SCC are not allowed to be left inservice when those indications are detected. These inspections are performed according to inspection procedures that are approved by regulatory authority. Actual inspections are witnessed by the Japan Power engineering and inspection corporation (JAPEIC)`s inspectors during data acquisition and analysis, and they issue inspection report to authority for review and approval. It is achieved high safety performance of steam generator through this method of inspections, however. some tube leakage problems were experienced in the past. To prevent recurrence of such events, government is conducting development and verification test program for new eddy current testing technology.

  8. Air Pollution

    Science.gov (United States)

    Air pollution is a mixture of solid particles and gases in the air. Car emissions, chemicals from factories, dust, ... a gas, is a major part of air pollution in cities. When ozone forms air pollution, it's ...

  9. A study on in-pipe inspection mobile robots, 3; Basic strategy of inspection path planning for inspection mobile robots

    Energy Technology Data Exchange (ETDEWEB)

    Fukuda, Toshio (Nagoya Univ. (Japan). Faculty of Engineering); Hosokai, Hidemi; Uemura, Masahiro

    1990-01-01

    This paper deals with inspection path planning for in-pipe inspection mobile robots which have the capability of moving through complicated pipeline networks. It is imperative that the robot systems have an inspection path planning system for such networks for their reasonable and rational operation, controlled by themselves or by the operators. The planning mainly requires two projects: the selection of the place to put the robot in or out, and the generation of the paths in the networks. This system provides the for complicated problems with plural inspection points using a basic strategy of systematically producing patterns and dividing partial problems of simple searches based on rules. (author).

  10. Instant Adobe Edge Inspect starter

    CERN Document Server

    Khan, Joseph

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This easy-to-understand Starter guide will get you up to speed with Adobe Edge Inspect quickly and with little effort.This book is for frontend web developers and designers who are developing and testing web applications targeted for mobile browsers. It's assumed that you have a basic understanding of creating web applications using HTML, CSS, and JavaScript, as well as being familiar with running web pages from local HTTP servers. Readers are a

  11. STIP-V Inspection Report

    Energy Technology Data Exchange (ETDEWEB)

    Saleh, Tarik A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Quintana, Matthew Estevan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Romero, Tobias J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-25

    The Los Alamos National Laboratory samples from the STIP-­V irradiation arrived at LANL on December 24th, 2014, after some delays en-­route from the Paul Scherrer Institute (PSI). The samples were transferred to the Wing 9 hot cells in early January and unpacked and inspected in cell with the Hirox Digital Optical microscope. The complete sample matrix of LANL specimens can be seen in table one. Due to space and budgetary issues, no TEM samples were sent back to LANL. Additionally the HT9-­WO, HT9-­Shot and T91-Shot samples are actually bend bars, rather than the tensile samples listed.

  12. Quality Inspection of Printed Texts

    DEFF Research Database (Denmark)

    Pedersen, Jesper Ballisager; Nasrollahi, Kamal; Moeslund, Thomas B.

    2016-01-01

    Inspecting the quality of printed texts has its own importance in many industrial applications. To do so, this paper proposes a grading system which evaluates the performance of the printing task using some quality measures for each character and symbols. The purpose of these grading system is two......-folded: for costumers of the printing and verification system, the overall grade used to verify if the text is of sufficient quality, while for printer's manufacturer, the detailed character/symbols grades and quality measurements are used for the improvement and optimization of the printing task. The proposed system...

  13. Backlit Keyboard Inspection Using Machine Vision

    Institute of Scientific and Technical Information of China (English)

    Der-Baau Perng; Hsiao-Wei Liu; Po-An Chen

    2015-01-01

    Abstract⎯A robust system for backlit keyboard inspection is revealed. The backlit keyboard not only has changeable diverse colors but also has the laser marking keys. The keys on the keyboard can be divided into regions of function keys, normal keys, and number keys. However, there might have some types of defects: incorrect illuminating area, non-uniform illumination of specified inspection region (IR), and incorrect luminance and intensity of individual key. Since the illumination features of backlit keyboard are too complex to inspect for human inspector in the production line, an auto-mated inspection system for the backlit keyboard is proposed in this paper. The system was designed into the operation module and inspection module. A set of image processing methods were developed for these defects inspection. Some experimental results demonstrate the robustness and effectiveness of the proposed system.

  14. Bidirectional transport of motor-driven cargoes in cell: A random walk with memory

    Science.gov (United States)

    Bhat, Deepak; Gopalakrishnan, Manoj

    2013-02-01

    Motor-driven bidirectional transport inside a cell is an intriguing phenomenon where multiple dyneins and kinesins drag cargoes and deliver them to specific locations. Quite often, both anterograde (plus) and retrograde (minus) directed motors reside simultaneously on the cargo and co-ordinate their activity such that the motion of the cargo looks like spells of plus directed and minus directed segments, with pauses in between. The stochastic tug-of-war model is widely used to analyze this motion, largely studied by computer simulations. Here, we present some analytical results for this model, such as the average durations of plus and minus-run segments and tug-of-war events as well as probabilities of persistence and reversal of directions following a tug-of-war. We show that cargo motion has memory in case of 2 dyneins and 1 kinesin driving together, while it is absent when only a dynein and a kinesin is involved.

  15. 46 CFR 38.05-10 - Installation of cargo tanks-general-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... including testing for the hull and integral tanks. In the application of the requirements for the hydrostatic test of the cargo tanks, the hydrostatic test shall in no case be less severe than the...

  16. User interface inspection methods a user-centered design method

    CERN Document Server

    Wilson, Chauncey

    2014-01-01

    User Interface Inspection Methods succinctly covers five inspection methods: heuristic evaluation, perspective-based user interface inspection, cognitive walkthrough, pluralistic walkthrough, and formal usability inspections. Heuristic evaluation is perhaps the best-known inspection method, requiring a group of evaluators to review a product against a set of general principles. The perspective-based user interface inspection is based on the principle that different perspectives will find different problems in a user interface. In the related persona-based inspection, colleagues assume the

  17. Hybridization of General Cargo Ships to meet the Required Energy Efficiency Design Index

    OpenAIRE

    Øverleir, Magnus Anders

    2015-01-01

    In this thesis a hybrid propulsion system is proposed for a general cargo ship with the aim to meet the required Energy Efficiency Design Index (EEDI). The study has investigated how a hybrid propulsion system will influence the ship s EEDI value and fuel economy. The central problem is the coming challenge for the general cargo segment meeting the required efficiency value. Especially small vessels (3 000-15 000 DWT) with high speed will have troubles complying with the stricter regulations....

  18. Experimental Research on Influence of Some Factors on Ejection Height of Cargo Projectile

    Institute of Scientific and Technical Information of China (English)

    郁浩; 王晓天; 李欣; 李纪敏

    2012-01-01

    Some factors influencing the cargo projectile's ejection height in different conditions were analyzed by using harmonic curve diagram and cluster method.The test results of the ejection height for a certain cargo projectile show that the wind speed and direction are the main influence factors.For given meteorological conditions,the applied environmental stress becomes the main cause,while the launching angle does not influence the ejection height.

  19. Design of a Large Span-Distributed Load Flying-Wing Cargo Airplane

    Science.gov (United States)

    Jernell, L. S.; Quartero, C. B.

    1977-01-01

    The design and operation of very large, long-range, subsonic cargo aircraft are considered. A design concept which distributes the payload along the wingspan to counterbalance the aerodynamic loads, with a resultant decrease in the in-flight wing bending moments and shear forces, is described. The decreased loading of the wing structure, coupled with the very thick wing housing the cargo, results in a relatively low overall structural weight in comparison to that of conventional aircraft.

  20. Underwater Photogrammetry and 3d Reconstruction of Marble Cargos Shipwreck

    Science.gov (United States)

    Balletti, C.; Beltrame, C.; Costa, E.; Guerra, F.; Vernier, P.

    2015-04-01

    Nowadays archaeological and architectural surveys are based on the acquisition and processing of point clouds, allowing a high metric precision, essential prerequisite for a good documentation. Digital image processing and laser scanner have changed the archaeological survey campaign, from manual and direct survey to a digital one and, actually, multi-image photogrammetry is a good solution for the underwater archaeology. This technical documentation cannot operate alone, but it has to be supported by a topographical survey to georeference all the finds in the same reference system. In the last years the Ca' Foscari and IUAV University of Venice are conducting a research on integrated survey techniques to support underwater metric documentation. The paper will explain all the phases regarding the survey's design, images acquisition, topographic measure and the data processing of two Roman shipwrecks in south Sicily. The cargos of the shipwrecks are composed by huge marble blocks, but they are different for morphological characteristic of the sites, for the depth and for their distribution on the seabed. Photogrammetrical and topographical surveys were organized in two distinct methods, especially for the second one, due to the depth that have allowed an experimentation of GPS RTK's measurements on one shipwreck. Moreover, this kind of three-dimensional documentation is useful for educational and dissemination aspect, for the ease of understanding by wide public.

  1. Mulheres em cargos profissionais de chefia: o paradoxo da igualdade

    Directory of Open Access Journals (Sweden)

    Fabia Alberton de Silva Galvane

    2015-12-01

    Full Text Available Resumo O artigo aqui apresentado foi construído a partir de informações obtidas em uma pesquisa realizada no ano de 2009, apresentada como Trabalho de Conclusão de Curso da Psicologia, ao Centro Universitário Barriga Verde - UNIBAVE (GALVANE, 2009. A pesquisa teve como objetivo geral verificar os sentidos produzidos por mulheres que ocupam cargos de chefia em indústrias de uma cidade do sul de Santa Catarina, Brasil. O modelo de pesquisa foi o qualitativo proposto por González Rey (2005. Os sujeitos da pesquisa foram sete mulheres e as informações obtidas por meio de entrevistas semiestruturadas. Neste artigo, propõe-se revisar informações obtidas e ampliar discussões outrora realizadas, utilizando-se das contribuições teóricas de Joan Scott e Judith Butler. Entre outras questões relevantes, o estudo sugere que as entrevistadas utilizam concepções baseadas em “certa essência feminina” como estratégia de visibilidade, permanência e poder no mercado de trabalho.

  2. Stochastic simulations of cargo transport by processive molecular motors.

    Science.gov (United States)

    Korn, Christian B; Klumpp, Stefan; Lipowsky, Reinhard; Schwarz, Ulrich S

    2009-12-28

    We use stochastic computer simulations to study the transport of a spherical cargo particle along a microtubule-like track on a planar substrate by several kinesin-like processive motors. Our newly developed adhesive motor dynamics algorithm combines the numerical integration of a Langevin equation for the motion of a sphere with kinetic rules for the molecular motors. The Langevin part includes diffusive motion, the action of the pulling motors, and hydrodynamic interactions between sphere and wall. The kinetic rules for the motors include binding to and unbinding from the filament as well as active motor steps. We find that the simulated mean transport length increases exponentially with the number of bound motors, in good agreement with earlier results. The number of motors in binding range to the motor track fluctuates in time with a Poissonian distribution, both for springs and cables being used as models for the linker mechanics. Cooperativity in the sense of equal load sharing only occurs for high values for viscosity and attachment time.

  3. Multivalent viral capsids with internal cargo for fibrin imaging.

    Directory of Open Access Journals (Sweden)

    Allie C Obermeyer

    Full Text Available Thrombosis is the cause of many cardiovascular syndromes and is a significant contributor to life-threatening diseases, such as myocardial infarction and stroke. Thrombus targeted imaging agents have the capability to provide molecular information about pathological clots, potentially improving detection, risk stratification, and therapy of thrombosis-related diseases. Nanocarriers are a promising platform for the development of molecular imaging agents as they can be modified to have external targeting ligands and internal functional cargo. In this work, we report the synthesis and use of chemically functionalized bacteriophage MS2 capsids as biomolecule-based nanoparticles for fibrin imaging. The capsids were modified using an oxidative coupling reaction, conjugating ∼90 copies of a fibrin targeting peptide to the exterior of each protein shell. The ability of the multivalent, targeted capsids to bind fibrin was first demonstrated by determining the impact on thrombin-mediated clot formation. The modified capsids out-performed the free peptides and were shown to inhibit clot formation at effective concentrations over ten-fold lower than the monomeric peptide alone. The installation of near-infrared fluorophores on the interior surface of the capsids enabled optical detection of binding to fibrin clots. The targeted capsids bound to fibrin, exhibiting higher signal-to-background than control, non-targeted MS2-based nanoagents. The in vitro assessment of the capsids suggests that fibrin-targeted MS2 capsids could be used as delivery agents to thrombi for diagnostic or therapeutic applications.

  4. 14 CFR 91.409 - Inspections.

    Science.gov (United States)

    2010-01-01

    ... procedures manual available and readily understandable to pilot and maintenance personnel containing, in... the name and address of the person responsible for scheduling the inspections required by the...

  5. Non-Destructive Inspection Lab (NDI)

    Data.gov (United States)

    Federal Laboratory Consortium — The NDI specializes in applied research, development and performance of nondestructive inspection procedures (flourescent penetrant, magnetic particle, ultrasonics,...

  6. Computer vision technology in log volume inspection

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Log volume inspection is very important in forestry research and paper making engineering. This paper proposed a novel approach based on computer vision technology to cope with log volume inspection. The needed hardware system was analyzed and the details of the inspection algorithms were given. A fuzzy entropy based on image enhancement algorithm was presented for enhancing the image of the cross-section of log. In many practical applications the cross-section is often partially invisible, and this is the major obstacle for correct inspection. To solve this problem, a robust Hausdorff distance method was proposed to recover the whole cross-section. Experiment results showed that this method was efficient.

  7. Robotic inspection technology-process an toolbox

    Energy Technology Data Exchange (ETDEWEB)

    Hermes, Markus [ROSEN Group (United States). R and D Dept.

    2005-07-01

    Pipeline deterioration grows progressively with ultimate aging of pipeline systems (on-plot and cross country). This includes both, very localized corrosion as well as increasing failure probability due to fatigue cracking. Limiting regular inspecting activities to the 'scrapable' part of the pipelines only, will ultimately result into a pipeline system with questionable integrity. The confidence level in the integrity of these systems will drop below acceptance levels. Inspection of presently un-inspectable sections of the pipeline system becomes a must. This paper provides information on ROSEN's progress on the 'robotic inspection technology' project. The robotic inspection concept developed by ROSEN is based on a modular toolbox principle. This is mandatory. A universal 'all purpose' robot would not be reliable and efficient in resolving the postulated inspection task. A preparatory Quality Function Deployment (QFD) analysis is performed prior to the decision about the adequate robotic solution. This enhances the serviceability and efficiency of the provided technology. The word 'robotic' can be understood in its full meaning of Recognition - Strategy - Motion - Control. Cooperation of different individual systems with an established communication, e.g. utilizing Bluetooth technology, support the robustness of the ROSEN robotic inspection approach. Beside the navigation strategy, the inspection strategy is also part of the QFD process. Multiple inspection technologies combined on a single carrier or distributed across interacting container must be selected with a clear vision of the particular goal. (author)

  8. 33 CFR 127.403 - Inspections.

    Science.gov (United States)

    2010-07-01

    ...) WATERFRONT FACILITIES WATERFRONT FACILITIES HANDLING LIQUEFIED NATURAL GAS AND LIQUEFIED HAZARDOUS GAS Waterfront Facilities Handling Liquefied Natural Gas Maintenance § 127.403 Inspections. The operator...

  9. Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin.

    Science.gov (United States)

    Weng, Liang; Enomoto, Atsushi; Miyoshi, Hiroshi; Takahashi, Kiyofumi; Asai, Naoya; Morone, Nobuhiro; Jiang, Ping; An, Jian; Kato, Takuya; Kuroda, Keisuke; Watanabe, Takashi; Asai, Masato; Ishida-Takagishi, Maki; Murakumo, Yoshiki; Nakashima, Hideki; Kaibuchi, Kozo; Takahashi, Masahide

    2014-09-17

    In clathrin-mediated endocytosis (CME), specificity and selectivity for cargoes are thought to be tightly regulated by cargo-specific adaptors for distinct cellular functions. Here, we show that the actin-binding protein girdin is a regulator of cargo-selective CME. Girdin interacts with dynamin 2, a GTPase that excises endocytic vesicles from the plasma membrane, and functions as its GTPase-activating protein. Interestingly, girdin depletion leads to the defect in clathrin-coated pit formation in the center of cells. Also, we find that girdin differentially interacts with some cargoes, which competitively prevents girdin from interacting with dynamin 2 and confers the cargo selectivity for CME. Therefore, girdin regulates transferrin and E-cadherin endocytosis in the center of cells and their subsequent polarized intracellular localization, but has no effect on integrin and epidermal growth factor receptor endocytosis that occurs at the cell periphery. Our results reveal that girdin regulates selective CME via a mechanism involving dynamin 2, but not by operating as a cargo-specific adaptor.

  10. El sistema de cargos en San Bernardino de Milpillas Chico, Durango

    Directory of Open Access Journals (Sweden)

    Chantal Cramaussel

    2013-01-01

    Full Text Available La principal estructura política de los tepehuanos es el sistema de cargos. En San Bernardino de Milpillas, Durango, los cargos de la Iglesia son diferentes a los del gobierno tradicional. Los segundos parecen apegarse más a las culturales locales, aunque los cargos de la Iglesia han sido objeto de transformaciones significativas para excluir a los ministros católicos en las ceremonias cristianas. La fiesta de la Candelaria, que precede a la toma de posesión de los nuevos “empleados”, muestra que los aspectos civiles de los cargos son indisociables de los rituales religiosos. Los cargos reunían funciones militares, judiciales y económicas, pero éstas han ido perdiendo vigencia por la violencia y por la compañía forestal, una notable fuente de recursos. Sin embargo, por el sistema de cargos los mestizos de Milpillas se han integrado a la organización política y la cultura de los tepehuanos.

  11. External forces influence the elastic coupling effects during cargo transport by molecular motors.

    Science.gov (United States)

    Berger, Florian; Keller, Corina; Klumpp, Stefan; Lipowsky, Reinhard

    2015-02-01

    Cellular transport is achieved by the cooperative action of molecular motors which are elastically linked to a common cargo. When the motors pull on the cargo at the same time, they experience fluctuating elastic strain forces induced by the stepping of the other motors. These elastic coupling forces can influence the motors' stepping and unbinding behavior and thereby the ability to transport cargos. Based on a generic single motor description, we introduce a framework that explains the response of two identical molecular motors to a constant external force. In particular, we relate the single motor parameters, the coupling strength and the external load force to the dynamics of the motor pair. We derive four distinct transport regimes and determine how the crossover lines between the regimes depend on the load force. Our description of the overall cargo dynamics takes into account relaxational displacements of the cargo caused by the unbinding of one motor. For large forces and weak elastic coupling these back-shifts dominate the displacements. To develop an intuitive understanding about motor cooperativity during cargo transport, we introduce a time scale for load sharing. This time scale allows us to predict how the regulation of single motor parameters influences the cooperativity. As an example, we show that up-regulating the single motor processivity enhances load sharing of the motor pair.

  12. Irradiation Effects for the Pulsed Fast Neutron Analysis (PFNA) Cargo Interrogation System

    Energy Technology Data Exchange (ETDEWEB)

    Slater, C.O.

    2001-02-02

    At the request of Safety and Ecology Corporation of Tennessee, radiation effects of the proposed Pulsed Fast Neutron Analysis (PFNA) Cargo Interrogation System have been examined. First, fissile cargo were examined to determine if a significant neutron signal would be observable during interrogation. Results indicated that ample multiplication would be seen for near critical bare targets. The water-reflected sphere showed relatively little multiplication. By implication, a fissile target shielded by hydrogenous cargo might not be detectable by neutron interrogation, particularly if reliance is placed on the neutron signal. The cargo may be detectable if use can be made of the ample increase in the photon signal. Second, dose rates were calculated at various locations within and just outside the facility building. These results showed that some dose rates may be higher than the target dose rate of 0.05 mrem/h. However, with limited exposure time, the total dose may be well below the allowed total dose. Lastly, estimates were made of the activation of structures and typical cargo. Most cargo will not be exposed long enough to be activated to levels of concern. On the other hand, portions of the structure may experience buildup of some radionuclides to levels of concern.

  13. Cargo-towing synthetic nanomachines: towards active transport in microchip devices.

    Science.gov (United States)

    Wang, Joseph

    2012-05-08

    This review article discusses the use of synthetic catalytic nano motors for cargo manipulations and for developing miniaturized lab-on-chip systems based on autonomous transport. The ability of using chemically-powered artificial nanomotors to capture, transport and release therapeutic payloads or nanostructured biomaterials represents one of the next major prospects for nanomotor development. The increased cargo-towing force of such self-propelled nanomotors, along with their precise motion control within microchannel networks, versatility and facile functionalization, pave the way to new integrated functional lab-on-a-chip powered by active transport and perform a series of tasks. Such use of cargo-towing artificial nanomotors has been inspired by on-chip kinesin molecular shuttles. Functionalized nano/microscale motors can thus be used to pick a selected nano/microscale chemical or biological payload target at the right place, transport and deliver them to a target location in a timely manner. Key challenges for using synthetic nanomachines for driving transport processes along microchannel networks are discussed, including loading and unloading of cargo and precise motion control, along with recent examples of related cargo manipulation processes and guided transport in lab-on-a-chip formats. The exciting research area of cargo-carrying catalytic man-made nanomachines is expected to grow rapidly, to lead to new lab-on-a-chip formats and to provide a wide range of future microchip opportunities.

  14. 49 CFR 180.415 - Test and inspection markings.

    Science.gov (United States)

    2010-10-01

    ... QUALIFICATION AND MAINTENANCE OF PACKAGINGS Qualification and Maintenance of Cargo Tanks § 180.415 Test and... cargo tank tested under § 180.407, except § 180.407(h)(2); and (vii) K-EPA27 for a cargo tank tested under § 180.407(h)(2) after October 1, 2004. Examples to paragraph (b). The markings “10-99 P, V,...

  15. 46 CFR 151.25-1 - Cargo tank.

    Science.gov (United States)

    2010-10-01

    ... continuously swept with air by means of blowers or other mechanical devices requiring power. (d) Ventilated... without the use of blowers or other mechanical devices requiring power (e.g., “chimney-effect”...

  16. The interactive on-site inspection system: An information management system to support arms control inspections

    Energy Technology Data Exchange (ETDEWEB)

    DeLand, S.M.; Widney, T.W.; Horak, K.E.; Caudell, R.B.; Grose, E.M.

    1996-12-01

    The increasing use of on-site inspection (OSI) to meet the nation`s obligations with recently signed treaties requires the nation to manage a variety of inspection requirements. This document describes a prototype automated system to assist in the preparation and management of these inspections.

  17. 9 CFR 354.121 - Ante-mortem inspection.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Ante-mortem inspection. 354.121 Section 354.121 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Procedures; Ante-Mortem Inspections § 354.121 Ante-mortem inspection. An ante-mortem inspection of...

  18. 9 CFR 590.925 - Inspection of imported egg products.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inspection of imported egg products... AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Imports § 590.925 Inspection of imported egg products. (a) Except as provided in § 590.960, egg products...

  19. 9 CFR 590.402 - Egg products inspection certificates.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Egg products inspection certificates... AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Certificates § 590.402 Egg products inspection certificates. (a) Upon request of the applicant or the...

  20. Shipboard monitoring of non-CO2 greenhouse gases in Asia and Oceania using commercially cargo vessels

    Science.gov (United States)

    Nara, H.; Tanimoto, H.; Mukai, H.; Nojiri, Y.; Tohjima, Y.; Machida, T.; Hashimoto, S.

    2011-12-01

    The National Institute for Environmental Studies (NIES) has been performing a long-term program for monitoring trace gases of atmospheric importance over the Pacific Ocean since 1995. The NIES Voluntary Observing Ships (NIES-VOS) program currently makes use of commercial cargo vessels because they operate regularly over fixed routes for long periods and sail over a wide area between various ports (e.g., between Japan and the United States, between Japan and Australia/New Zealand, and between Japan and southeast Asia). This program allows systematic and continuous measurements of non-CO2 greenhouse gases, providing long-term datasets for background air over the Pacific Ocean and regionally polluted air around east Asia. We observe both long-lived greenhouse gases (e.g., carbon dioxide) and short-lived air pollutants (e.g., tropospheric ozone, carbon monoxide) on a continuous basis. Flask samples are collected for later laboratory analysis of carbon dioxide, methane, nitrous oxide, and carbon monoxide by using gas chromatographic techniques. In addition, we recently installed cavity ringdown spectrometers for high-resolution measurement of methane and carbon dioxide to capture their highly variable features in regionally polluted air around southeast Asia (e.g., Hong Kong, Thailand, Singapore, Malaysia, Indonesia and Philippine), which is now thought to be a large source due to expanding socioeconomic activities as well as biomass burnings. Contrasting the Japan-Australia/New Zealand and Japan-southeast Asia cruises revealed regional characteristics of sources and sinks of these atmospherically important species, suggesting the existence of additional sources for methane, nitrous oxides, and carbon monoxide in this tropical Asian region.

  1. 7 CFR 982.446 - Inspection documentation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Inspection documentation. 982.446 Section 982.446 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... WASHINGTON Administrative Rules and Regulations § 982.446 Inspection documentation. Pursuant to §...

  2. 14 CFR 65.91 - Inspection authorization.

    Science.gov (United States)

    2010-01-01

    ..., for at least the 2-year period before the date he applies, in maintaining aircraft certificated and... necessary to properly inspect airframes, powerplants, propellers, or any related part or appliance; and (5) Pass a written test on his ability to inspect according to safety standards for returning aircraft...

  3. 45 CFR 1309.33 - Inspection.

    Science.gov (United States)

    2010-10-01

    ... FACILITIES PURCHASE, MAJOR RENOVATION AND CONSTRUCTION Modular Units § 1309.33 Inspection. A grantee which purchases a modular unit with grant funds or receives approval of a continuing purchase must have the modular unit inspected by a licensed engineer or architect within 15 calendar days of its installation...

  4. ANNUAL RADIOACTIVE WASTE TANK INSPECTION PROGRAM 2008

    Energy Technology Data Exchange (ETDEWEB)

    West, B.; Waltz, R.

    2009-06-11

    Aqueous radioactive wastes from Savannah River Site (SRS) separations and vitrification processes are contained in large underground carbon steel tanks. Inspections made during 2008 to evaluate these vessels and other waste handling facilities along with evaluations based on data from previous inspections are the subject of this report.

  5. Automatic visual inspection of hybrid microcircuits

    Energy Technology Data Exchange (ETDEWEB)

    Hines, R.E.

    1980-05-01

    An automatic visual inspection system using a minicomputer and a video digitizer was developed for inspecting hybrid microcircuits (HMC) and thin-film networks (TFN). The system performed well in detecting missing components on HMCs and reduced the testing time for each HMC by 75%.

  6. Annual Radioactive Waste Tank Inspection Program - 1997

    Energy Technology Data Exchange (ETDEWEB)

    McNatt, F.G. [Westinghouse Savannah River Company, AIKEN, SC (United States)

    1998-05-01

    Aqueous radioactive wastes from Savannah River Site (SRS) separations processes are contained in large underground carbon steel tanks. Inspections made during 1997 to evaluate these vessels, and evaluations based on data accrued by inspections performed since the tanks were constructed are the subject of this report.

  7. 47 CFR 2.936 - FCC inspection.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false FCC inspection. 2.936 Section 2.936 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL... Authorization § 2.936 FCC inspection. Upon reasonable request, each responsible party shall submit the...

  8. Annual radioactive waste tank inspection program: 1995

    Energy Technology Data Exchange (ETDEWEB)

    McNatt, F.G. Sr.

    1996-04-01

    Aqueous radioactive wastes from Savannah River Site (SRS) separations processes are contained in large underground carbon steel tanks. Inspections made during 1995 to evaluate these vessels and evaluations based on data accrued by inspections performed since the tanks were constructed are the subject of this report

  9. Annual radioactive waste tank inspection program - 1996

    Energy Technology Data Exchange (ETDEWEB)

    McNatt, F.G.

    1997-04-01

    Aqueous radioactive wastes from Savannah River Site (SRS) separations processes are contained in large underground carbon steel tanks. Inspections made during 1996 to evaluate these vessels, and evaluations based on data accrued by inspections performed since the tanks were constructed, are the subject of this report.

  10. Laser Damage Inspection Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Salmon, J T; Brase, J M; Bliss, E S; Carrano, C J; Kegelmeyer, L M; Miller, M G; Orth, C D; Sacks, R A

    2001-02-26

    Large, high-power laser systems are often designed as reimaging multipass cavities to maximize the extraction of energy from the amplifiers. These multipass cavities often have vacuum spatial filters that suppress the growth of beam instability via B-integral effects. These spatial filters also relay images of laser damage, often nearly superimposing these images in common planes. Also, the fluence damage threshold limits the minimum size of the optics. When used as vacuum barriers in the spatial filters, these large optics present a safety hazard from the risk of implosion if the laser damage were sufficiently large. The objective of the project was to develop algorithms and methods for optical detection and characterization of laser-induced damage of optics. The system should detect small defects (about 5% of the critical size), track their growth over multiple laser shots, and characterize the defects accurately so that the optic can be replaced (at 25% of the critical size) and, hence, minimize the risk of implosion. The depth of field must be short enough to isolate the damaged vacuum barrier from other damaged optics in the beamline, and the system should also be capable of inspecting other optics in the beamline, since damage on one optic can subsequently damage subsequent optics. Laser induced damage starts as a small (<<1mm) crater and grows as material is removed on subsequent laser shots. The highly fractured rough surface of the crater scatters light from the illuminating inspection beam. This scattered light is imaged by the inspection system. Other types of defects may occur as well including inclusions in the bulk glass, tooling marks, and surface contamination. This report will discuss the detection and characterization of crater-like surface defects although the general techniques may prove useful for other types of defects. The work described here covers the development of an image processing approach and specific algorithms for defect detection

  11. Working session 2: Tubing inspection

    Energy Technology Data Exchange (ETDEWEB)

    Guerra, J. [Tecnatom, S.A. San Sebastian de los Reyes, Madrid (Spain); Tapping, R.L. [AECL, Chalk River, Ontario (Canada)

    1997-02-01

    This session was attended by delegates from 10 countries, and four papers were presented. A wide range of issues was tabled for discussion. Realizing that there was limited time available for more detailed discussion, three topics were chosen for the more detailed discussion: circumferential cracking, performance demonstration (to focus on POD and sizing), and limits of methods. Two other subsessions were organized: one dealt with some challenges related to the robustness of current inspection methods, especially with respect to leaving cracked tubes in service, and the other with developing a chart of current NDE technology with recommendations for future development. These three areas are summarized in turn, along with conclusions and/or recommendations. During the discussions there were four presentations. There were two (Canada, Japan) on eddy current probe developments, both of which addressed multiarray probes that would detect a range of flaws, one (Spain) on circumferential crack detection, and one (JRC, Petten) on the recent PISC III results.

  12. Dielectric inspection of erythrocyte morphology

    Science.gov (United States)

    Hayashi, Yoshihito; Oshige, Ikuya; Katsumoto, Yoichi; Omori, Shinji; Yasuda, Akio; Asami, Koji

    2008-05-01

    We performed a systematic study of the sensitivity of dielectric spectroscopy to erythrocyte morphology. Namely, rabbit erythrocytes of four different shapes were prepared by precisely controlling the pH of the suspending medium, and their complex permittivities over the frequency range from 0.1 to 110 MHz were measured and analyzed. Their quantitative analysis shows that the characteristic frequency and the broadening parameter of the dielectric relaxation of interfacial polarization are highly specific to the erythrocyte shape, while they are insensitive to the cell volume fraction. Therefore, these two dielectric parameters can be used to differentiate erythrocytes of different shapes, if dielectric spectroscopy is applied to flow-cytometric inspection of single blood cells. In addition, we revealed the applicability and limitations of the analytical theory of interfacial polarization to explain the experimental permittivities of non-spherical erythrocytes.

  13. Visual Inspection for Caries Detection

    DEFF Research Database (Denmark)

    Gimenez, T; Piovesan, C; Braga, M M

    2015-01-01

    We aimed to perform a systematic review including a meta-analysis to evaluate the overall accuracy of visual methods for detecting carious lesions and to identify possible sources of heterogeneity among the studies included. Two reviewers searched PubMed, Embase, Scopus, and other sources through...... July 2014 to identify published and nonpublished studies in English. Studies of visual inspection were included that 1) assessed accuracy of the method in detecting caries lesions; 2) were performed on occlusal, proximal, or free smooth surfaces in primary or permanent teeth; 3) had a reference...... (from 5,808 articles initially identified) and 1 abstract (from 168) met the inclusion criteria. In general, the analysis demonstrated that the visual method had good accuracy for detecting caries lesions. Although laboratory and clinical studies have presented similar accuracy, clinically obtained...

  14. Surface inspection using FTIR spectroscopy

    Science.gov (United States)

    Powell, G. L.; Smyrl, N. R.; Williams, D. M.; Meyers, H. M., III; Barber, T. E.; Marrero-Rivera, M.

    1995-01-01

    The use of reflectance Fourier transform infrared (FTIR) spectroscopy as a tool for surface inspection is described. Laboratory instruments and portable instruments can support remote sensing probes that can map chemical contaminants on surfaces with detection limits under the best of conditions in the sub-nanometer range, i.e.. near absolute cleanliness, excellent performance in the sub-micrometer range, and useful performance for films tens of microns thick. Examples of discovering and quantifying contamination such as mineral oils and greases, vegetable oils, and silicone oils on aluminum foil, galvanized sheet steel, smooth aluminum tubing, and sandblasted 7075 aluminum alloy and D6AC steel. The ability to map in time and space the distribution of oil stains on metals is demonstrated. Techniques associated with quantitatively applying oils to metals, subsequently verifying the application, and non-linear relationships between reflectance and the quantity oil are described.

  15. DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family

    Science.gov (United States)

    Franch, Oskar; Iacovelli, Federico; Falconi, Mattia; Juul, Sissel; Ottaviani, Alessio; Benvenuti, Claudia; Biocca, Silvia; Ho, Yi-Ping; Knudsen, Birgitta R.; Desideri, Alessandro

    2016-07-01

    In the present study we investigate the mechanism behind temperature controlled cargo uptake using a truncated octahedral DNA cage scaffold functionalized with one, two, three or four hairpin forming DNA strands inserted in one corner of the structure. This investigation was inspired by our previous demonstration of temperature controlled reversible encapsulation of the cargo enzyme, horseradish peroxidase, in the cage with four hairpin forming strands. However, in this previous study the mechanism of cargo uptake was not directly addressed (Juul, et al., Temperature-Controlled Encapsulation and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage, ACS Nano, 2013, 7, 9724-9734). In the present study we use a combination of molecular dynamics simulations and in vitro analyses to unravel the mechanism of cargo uptake in hairpin containing DNA cages. We find that two hairpin forming strands are necessary and sufficient to facilitate efficient cargo uptake, which argues against a full opening-closing of one corner of the structure being responsible for encapsulation. Molecular dynamics simulations were carried out to evaluate the atomistic motions responsible for encapsulation and showed that the two hairpin forming strands facilitated extension of at least one of the face surfaces of the cage scaffold, allowing entrance of the cargo protein into the cavity of the structure. Hence, the presented data demonstrate that cargo uptake does not involve a full opening of the structure. Rather, the uptake mechanism represents a feature of increased flexibility integrated in this nanocage structure upon the addition of at least two hairpin-forming strands.In the present study we investigate the mechanism behind temperature controlled cargo uptake using a truncated octahedral DNA cage scaffold functionalized with one, two, three or four hairpin forming DNA strands inserted in one corner of the structure. This investigation was inspired by our previous

  16. Modifications to the INSPECT model

    Energy Technology Data Exchange (ETDEWEB)

    Dickinson, S. [AEA Technology, Winfrith (United Kingdom); Sims, H.E. [AEA Technology, Harwell (United Kingdom)

    1996-12-01

    The prediction of iodine behaviour in the containment of a PWR following a loss of coolant accident requires a reliable model of the chemistry of iodine in aqueous solution. The INSPECT model, which was developed several years ago, contains a large number of the relevant chemical reactions of iodine and water radiation chemistry. Since the reactions set was first assembled, however, new data on rate constants and mechanisms have become available. In addition, the application of the model to various small-scale experiments has revealed problems in the modelling of some reactions, leading to an under-prediction of the iodine volatility at high pH, although the experiments have demonstrated that the high pH volatility remains satisfactory low. This paper describes the modifications which have been made to the INSPECT model to take account of new data and to improve the modelling where appropriate. The main changes which have been made to the reaction set are as follows: - The rate constants and activation energies for the reactions describing the radiolysis of water have been updated in with recent assessments, and the temperature dependence of the G value for the primary species have been accordance taken into account, - The mechanism and rates of I{sub 2} hydrolysis have been modified in accordance with the latest assessments of this reaction, - The mechanism for the reaction of I{sub 2} with H{sub 2}O{sub 2} has been changed to a form which produces a more realistic pH dependence under neutral and alkaline conditions, - An addition mechanism for the disproportionation of the O{sub 2} ion has been included, reflecting experimental observations that this reaction has a significant first-order component under all but the purest conditions, - Atomic I is treated as a volatile species, with a partition coefficient of 1.9 at 298 K. (Abstract Truncated)

  17. FAM21 directs SNX27-retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus.

    Science.gov (United States)

    Lee, Seongju; Chang, Jaerak; Blackstone, Craig

    2016-03-09

    The endosomal network maintains cellular homeostasis by sorting, recycling and degrading endocytosed cargoes. Retromer organizes the endosomal sorting pathway in conjunction with various sorting nexin (SNX) proteins. The SNX27-retromer complex has recently been identified as a major endosomal hub that regulates endosome-to-plasma membrane recycling by preventing lysosomal entry of cargoes. Here, we show that SNX27 directly interacts with FAM21, which also binds retromer, within the Wiskott-Aldrich syndrome protein and SCAR homologue (WASH) complex. This interaction is required for the precise localization of SNX27 at an endosomal subdomain as well as for recycling of SNX27-retromer cargoes. Furthermore, FAM21 prevents cargo transport to the Golgi apparatus by controlling levels of phosphatidylinositol 4-phosphate, which facilitates cargo dissociation at the Golgi. Together, our results demonstrate that the SNX27-retromer-WASH complex directs cargoes to the plasma membrane by blocking their transport to lysosomes and the Golgi.

  18. Design inspections for systems undergoing design modifications

    Energy Technology Data Exchange (ETDEWEB)

    Grimes, B.K.; Norkin, D.P.

    1987-01-01

    The US Nuclear Regulatory Commission's (NRC's) Office of Inspection and Enforcement (IE) has conducted direct inspections (integrated design inspections) of the technical aspects of the nuclear plant design process for several plants under construction. It has also evaluated independent design verification programs and engineering assurance programs at a number of other plants under construction. Many of the lessons learned from these construction phase efforts are directly applicable to operating plants undergoing major modifications. This has been confirmed by IE direct inspections of the design aspects of safety systems outage modifications, which have identified significant potential safety-related deficiencies. The paper discusses methodology for design inspections; failure to maintain up-to-date design basis documentation; and lessons learned common to plants under construction and undergoing major modifications.

  19. On automatic visual inspection of reflective surfaces

    DEFF Research Database (Denmark)

    Kulmann, Lionel

    1995-01-01

    surveyed visual inspection system design methods and presented available image processing hardware to perform high resolution image capture. We present general usable practical visual inspection system solutions, when performing high resolution visual inspection of surfaces. We have presented known and new......This thesis descrbes different methods to perform automatic visual inspection of reflective manufactured products, with the aim of increasing productivity, reduce cost and improve the quality level of the production. We investigate two different systems performing automatic visual inspection...... in algorithms for detecting 3-dimensional surface damages based on images from a novel structured lighting setup enhancing the appearance of these defects in specular surfaces. A hardware implementable polynomial classifier structure has been described and compared to better known techniques based...

  20. Subsea Infrastructure Inspection: A Review Study

    DEFF Research Database (Denmark)

    Mai, Christian; Pedersen, Simon; Hansen, Leif

    2016-01-01

    as very skilled pilot and crews. The paper examines the existing challenges related to the sub-sea inspection in general, the ROVs, AUVs and semi-autonomous ROVs advantages and disadvantages in different subsea inspec-tion applications. Replacing the ROVs with Semi or fully-Autonomous Underwa-ter Vehicle...... of the offshore pipeline inspections are currently committed using Towed or Remotely Operated Vehicle (ROV) systems. It is well-known that the ROVs are very time-consuming and expensive to operate, with respect to the fact that they require a relatively large support ship to accommodate the equipment as well...... (S-AUVs) can significantly change the inspections of infrastructure, as these vehicles could be much cheaper to deploy. S-AUVs can potentially conduct faster data collection and provide higher inspection data quality. However, there are still some technical challenges related to: underwater wireless...

  1. Optical inspection of EPL stencil masks

    Science.gov (United States)

    Lee, Po-Tung; Engelstad, Roxann L.; Lovell, Edward G.; Kawata, Shintaro; Hirayanagi, Noriyuki; Sogard, Michael R.

    2003-06-01

    We are now at a major junction in lithography where non-optical lithographies, such as Electron Projection Lithography (EPL) [1], are being introduced. The mask used in EPL is a non-transparent silicon substrate with a thin silicon (~2μm) membrane with openings for electrons to pass through acting as a scatterer. This must be inspected as defects may cause printable defects. Initial mask inspection work has used SEM inspection to find these defects. However, we have historically used optical mask inspection tools, utilising wavelengths at or above what we are using for imaging, to qualify masks. This technology has been increasingly difficult to sustain as we have moved from imaging using mercury lamp based sources to pulsed excimer laser based sources that are not very suited to the inspection imaging. Indeed, review of defects found has moved from optical microscopes to SEM based tools. Inspection tools have also evolved, with the first SEM based mask inspection tools being developed to find the smallest defects, however these have the penalty of very low throughput. We will show the potential of using optical systems for the transmissive inspection of these EPL masks. The high potential of existing tools will be shown together with the need for a next generation of inspection tools. We will show that simulations indicate that an inspection source with 193nm wavelength would be required for the detection of 50nm defects on a mask used to print 70nm dense lines. It will also be shown how the position of the defect within the membrane greatly influences detection as well as the implications of moving to a thinner silicon membrane.

  2. ANNUAL RADIOACTIVE WASTE TANK INSPECTION PROGRAM 2009

    Energy Technology Data Exchange (ETDEWEB)

    West, B.; Waltz, R.

    2010-06-21

    Aqueous radioactive wastes from Savannah River Site (SRS) separations and vitrification processes are contained in large underground carbon steel tanks. Inspections made during 2009 to evaluate these vessels and other waste handling facilities along with evaluations based on data from previous inspections are the subject of this report. The 2009 inspection program revealed that the structural integrity and waste confinement capability of the Savannah River Site waste tanks were maintained. All inspections scheduled per LWO-LWE-2008-00423, HLW Tank Farm Inspection Plan for 2009, were completed. All Ultrasonic measurements (UT) performed in 2009 met the requirements of C-ESG-00006, In-Service Inspection Program for High Level Waste Tanks, Rev. 1, and WSRC-TR-2002-00061, Rev.4. UT inspections were performed on Tank 29 and the findings are documented in SRNL-STI-2009-00559, Tank Inspection NDE Results for Fiscal Year 2009, Waste Tank 29. Post chemical cleaning UT measurements were made in Tank 6 and the results are documented in SRNL-STI-2009-00560, Tank Inspection NDE Results Tank 6, Including Summary of Waste Removal Support Activities in Tanks 5 and 6. A total of 6669 photographs were made and 1276 visual and video inspections were performed during 2009. Twenty-Two new leaksites were identified in 2009. The locations of these leaksites are documented in C-ESR-G-00003, SRS High Level Waste Tank Leaksite Information, Rev.4. Fifteen leaksites at Tank 5 were documented during tank wall/annulus cleaning activities. Five leaksites at Tank 6 were documented during tank wall/annulus cleaning activities. Two new leaksites were identified at Tank 19 during waste removal activities. Previously documented leaksites were reactivated at Tanks 5 and 12 during waste removal activities. Also, a very small amount of additional leakage from a previously identified leaksite at Tank 14 was observed.

  3. Inspection of advanced computational lithography logic reticles using a 193-nm inspection system

    Science.gov (United States)

    Yu, Ching-Fang; Lin, Mei-Chun; Lai, Mei-Tsu; Hsu, Luke T. H.; Chin, Angus; Lee, S. C.; Yen, Anthony; Wang, Jim; Chen, Ellison; Wu, David; Broadbent, William H.; Huang, William; Zhu, Zinggang

    2010-09-01

    We report inspection results of early 22-nm logic reticles designed with both conventional and computational lithography methods. Inspection is performed using a state-of-the-art 193-nm reticle inspection system in the reticleplane inspection mode (RPI) where both rule-based sensitivity control (RSC) and a newer modelbased sensitivity control (MSC) method are tested. The evaluation includes defect detection performance using several special test reticles designed with both conventional and computational lithography methods; the reticles contain a variety of programmed critical defects which are measured based on wafer print impact. Also included are inspection results from several full-field product reticles designed with both conventional and computational lithography methods to determine if low nuisance-defect counts can be achieved. These early reticles are largely single-die and all inspections are performed in the die-to-database inspection mode only.

  4. 21 CFR 1316.08 - Consent to inspection.

    Science.gov (United States)

    2010-04-01

    ... constitutional right not to have an administrative inspection made without an administrative inspection warrant; (2) That he has right to refuse to consent to such an inspection; (3) That anything of...

  5. 9 CFR 500.7 - Refusal to grant inspection.

    Science.gov (United States)

    2010-01-01

    ... REGULATORY REQUIREMENTS UNDER THE FEDERAL MEAT INSPECTION ACT AND THE POULTRY PRODUCTS INSPECTION ACT RULES... Federal inspection because an applicant: (1) Does not have a HACCP plan as required by part 417 of...

  6. Toxicological Assessment of ISS Air Quality: SpaceX-2 First Ingress

    Science.gov (United States)

    Meyers, Valerie

    2013-01-01

    One mini-grab sample container (M-GSC) was collected by crew members onboard ISS during first ingress into SpaceX-2 on March 3, 2013, three days after late cargo loading and a pre-launch clean air purge. Recoveries of the three surrogate standards from the m-GSC were: 13C-acetone, 97%; fluorobenzene, 95%; and chlorobenzene, 68%.

  7. 76 FR 10085 - Notice of Applications for Certificates of Public Convenience and Necessity and Foreign Air...

    Science.gov (United States)

    2011-02-23

    ... Office of the Secretary Notice of Applications for Certificates of Public Convenience and Necessity and..., 2011 The following Applications for Certificates of Public Convenience and Necessity and Foreign Air... Airlines, Inc., d/b/a Alpha Cargo, and for reissuance of its certificate of public convenience...

  8. A Systems Engineering Approach to Analyzing Weather Input Sensitivities of the Joint Precision Air Drop System

    Science.gov (United States)

    2007-06-01

    British airborne troops “watched in despair as thirty-five Stirling bomber-cargo planes dropped supplies everywhere but on the [drop] zones. Of eighty...must fly the aircraft to a specific point in the sky , known as the Computed Air Release Point (CARP). The CARP is calculated using variables such as

  9. UF{sub 6} cylinder inspections at PGDP

    Energy Technology Data Exchange (ETDEWEB)

    Lamb, G.W.; Whinnery, W.N. [Martin Marietta Energy Systems, Inc., Paducah, KY (United States)

    1991-12-31

    Routine inspections of all UF{sub 6} cylinders at the Paducah Gaseous Diffusion Plant have been mandated by the Department of Energy. A specific UF{sub 6} cylinder inspection procedure for what items to inspect and training for the operators prior to inspection duty are described. The layout of the cylinder yards and the forms used in the inspections are shown. The large number of cylinders (>30,000) to inspect and the schedule for completion on the mandated time table are discussed. Results of the inspections and the actions to correct the deficiencies are explained. Future inspections and movement of cylinders for relocation of certain cylinder yards are defined.

  10. Advanced maintenance, inspection & repair technology for nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Hinton, B.M.

    1994-12-31

    Maintenance, inspection, and repair technology for nuclear power plants is outlined. The following topics are discussed: technology for reactor systems, reactor refueling bridge, fuel inspection system, fuel shuffling software, fuel reconstitution, CEA/RCCA/CRA inspection, vessel inspection capabilities, CRDM inspection and repair, reactor internals inspection and repair, stud tensioning system, stud/nut cleaning system, EDM machining technology, MI Cable systems, core exit T/C nozzle assemblies, technology for steam generators, genesis manipulator systems, ECT, UT penetrant inspections, steam generator repair and cleaning systems, technology for balance of plant, heat exchangers, piping and weld inspections, and turbogenerators.

  11. Inspection and in situ impedance measurements for ballast water tanks

    NARCIS (Netherlands)

    Zhang, X.; Buter, S.; Ferrari, G.; Prent, C.S.W.

    2012-01-01

    The application of coatings in ballast water tanks is critical for the safety of cargo ships. International Maritime Organization (IMO) has delivered a standard for the protection of water ballast tanks in which new built cargo vessels have to comply with {resolution MSC.215(82)}. In case the proced

  12. The iTRAPs: Guardians of Synaptic Vesicle Cargo Retrieval During Endocytosis.

    Science.gov (United States)

    Gordon, Sarah L; Cousin, Michael A

    2016-01-01

    The reformation of synaptic vesicles (SVs) during endocytosis is essential for the maintenance of neurotransmission in central nerve terminals. Newly formed SVs must be generated with the correct protein cargo in the correct stoichiometry to be functional for exocytosis. Classical clathrin adaptor protein complexes play a key role in sorting and clustering synaptic vesicle cargo in this regard. However it is becoming increasingly apparent that additional "fail-safe" mechanisms exist to ensure the accurate retrieval of essential cargo molecules. For example, the monomeric adaptor proteins AP180/CALM and stonin-2 are required for the efficient retrieval of synaptobrevin II (sybII) and synaptotagmin-1 respectively. Furthermore, recent studies have revealed that sybII and synaptotagmin-1 interact with other SV cargoes to ensure a high fidelity of retrieval. These cargoes are synaptophysin (for sybII) and SV2A (for synaptotagmin-1). In this review, we summarize current knowledge regarding the retrieval mechanisms for both sybII and synaptotagmin-1 during endocytosis. We also define and set criteria for a new functional group of SV molecules that facilitate the retrieval of their interaction partners. We have termed these molecules intrinsic trafficking partners (iTRAPs) and we discuss how the function of this group impacts on presynaptic performance in both health and disease.

  13. Spiders (Araneae) Found in Bananas and Other International Cargo Submitted to North American Arachnologists for Identification.

    Science.gov (United States)

    Vetter, Richard S; Crawford, Rodney L; Buckle, Donald J

    2014-11-01

    Spiders found in international cargo brought into North America are sometimes submitted to arachnologists for identification. Often, these spiders are presumed to be of medical importance because of size or a submitter's familiarity with a toxic spider genus from the continent of origin. Starting in 2006, requests were made for spiders found in international cargo brought into North America, in addition to the specimens from similar cargo shipments already in our museum collections. This was an ad hoc study that allowed us to focus on spiders of concern to the discoverer. We identified 135 spiders found in international cargo. A key for the most common species is provided. The most frequently submitted spiders were the pantropical huntsman spider, Heteropoda venatoria (L.) (Sparassidae), and the redfaced banana spider, Cupiennius chiapanensis Medina Soriano (Ctenidae). Spiders of medical importance were rare. The most common cargo from which spiders were submitted was bananas with most specimens coming from Central America, Ecuador, or Colombia. Lack of experience with nonnative fauna caused several experienced American arachnologists to misidentify harmless ctenid spiders (C. chiapanensis, spotlegged banana spider, Cupiennius getazi Simon) as highly toxic Phoneutria spiders. These misidentifications could have led to costly, unwarranted prophylactic eradication measures, unnecessary employee health education, heightened employee anxiety and spoilage when perishable goods are left unloaded due to safety concerns.

  14. LUCID: A Quantitative Assay of ESCRT-Mediated Cargo Sorting into Multivesicular Bodies.

    Science.gov (United States)

    Nickerson, Daniel P; Merz, Alexey J

    2015-12-01

    Endosomes are transportation nodes, mediating selective transport of soluble and transmembrane cargos to and from the Golgi apparatus, plasma membrane and lysosomes. As endosomes mature to become multivesicular bodies (MVBs), Endosomal Sorting Complexes Required for Transport (ESCRTs) selectively incorporate transmembrane cargos into vesicles that bud into the endosome lumen. Luminal vesicles and their cargoes are targeted for destruction when MVBs fuse with lysosomes. Common assays of endosomal luminal targeting, including fluorescence microscopy and monitoring of proteolytic cargo maturation, possess significant limitations. We present a quantitative assay system called LUCID (LUCiferase reporter of Intraluminal Deposition) that monitors exposure of chimeric luciferase-cargo reporters to cytosol. Luciferase-chimera signal increases when sorting to the endosome lumen is disrupted, and silencing of signal from the chimera depends upon luminal delivery of the reporter rather than proteolytic degradation. The system presents several advantages, including rapidity, microscale operation and a high degree of reproducibility that enables detection of subtle phenotypic differences. Luciferase reporters provide linear signal over an extremely broad dynamic range, allowing analysis of reporter traffic even at anemic levels of expression. Furthermore, LUCID reports transport kinetics when applied to inducible trafficking reporters.

  15. Molecular motors pulling cargos in the viscoelastic cytosol: how power strokes beat subdiffusion.

    Science.gov (United States)

    Goychuk, Igor; Kharchenko, Vasyl O; Metzler, Ralf

    2014-08-21

    The discovery of anomalous diffusion of larger biopolymers and submicron tracers such as endogenous granules, organelles, or virus capsids in living cells, attributed to the viscoelastic nature of the cytoplasm, provokes the question whether this complex environment equally impacts the active intracellular transport of submicron cargos by molecular motors such as kinesins: does the passive anomalous diffusion of free cargo always imply its anomalously slow active transport by motors, the mean transport distance along microtubule growing sublinearly rather than linearly in time? Here we analyze this question within the widely used two-state Brownian ratchet model of kinesin motors based on the continuous-state diffusion along microtubules driven by a flashing binding potential, where the cargo particle is elastically attached to the motor. Depending on the cargo size, the loading force, the amplitude of the binding potential, the turnover frequency of the molecular motor enzyme, and the linker stiffness we demonstrate that the motor transport may turn out either normal or anomalous, as indeed measured experimentally. We show how a highly efficient normal active transport mediated by motors may emerge despite the passive anomalous diffusion of the cargo, and study the intricate effects of the elastic linker. Under different, well specified conditions the microtubule-based motor transport becomes anomalously slow and thus significantly less efficient.

  16. Drive the Car(go)s—New Modalities to Control Cargo Trafficking in Live Cells

    Science.gov (United States)

    Mondal, Payel; Khamo, John S.; Krishnamurthy, Vishnu V.; Cai, Qi; Zhang, Kai

    2017-01-01

    Synaptic transmission is a fundamental molecular process underlying learning and memory. Successful synaptic transmission involves coupled interaction between electrical signals (action potentials) and chemical signals (neurotransmitters). Defective synaptic transmission has been reported in a variety of neurological disorders such as Autism and Alzheimer’s disease. A large variety of macromolecules and organelles are enriched near functional synapses. Although a portion of macromolecules can be produced locally at the synapse, a large number of synaptic components especially the membrane-bound receptors and peptide neurotransmitters require active transport machinery to reach their sites of action. This spatial relocation is mediated by energy-consuming, motor protein-driven cargo trafficking. Properly regulated cargo trafficking is of fundamental importance to neuronal functions, including synaptic transmission. In this review, we discuss the molecular machinery of cargo trafficking with emphasis on new experimental strategies that enable direct modulation of cargo trafficking in live cells. These strategies promise to provide insights into a quantitative understanding of cargo trafficking, which could lead to new intervention strategies for the treatment of neurological diseases. PMID:28163671

  17. Cargo binding promotes KDEL receptor clustering at the mammalian cell surface.

    Science.gov (United States)

    Becker, Björn; Shaebani, M Reza; Rammo, Domenik; Bubel, Tobias; Santen, Ludger; Schmitt, Manfred J

    2016-06-29

    Transmembrane receptor clustering is a ubiquitous phenomenon in pro- and eukaryotic cells to physically sense receptor/ligand interactions and subsequently translate an exogenous signal into a cellular response. Despite that receptor cluster formation has been described for a wide variety of receptors, ranging from chemotactic receptors in bacteria to growth factor and neurotransmitter receptors in mammalian cells, a mechanistic understanding of the underlying molecular processes is still puzzling. In an attempt to fill this gap we followed a combined experimental and theoretical approach by dissecting and modulating cargo binding, internalization and cellular response mediated by KDEL receptors (KDELRs) at the mammalian cell surface after interaction with a model cargo/ligand. Using a fluorescent variant of ricin toxin A chain as KDELR-ligand (eGFP-RTA(H/KDEL)), we demonstrate that cargo binding induces dose-dependent receptor cluster formation at and subsequent internalization from the membrane which is associated and counteracted by anterograde and microtubule-assisted receptor transport to preferred docking sites at the plasma membrane. By means of analytical arguments and extensive numerical simulations we show that cargo-synchronized receptor transport from and to the membrane is causative for KDELR/cargo cluster formation at the mammalian cell surface.

  18. The iTRAPs: guardians of synaptic vesicle cargo retrieval during endocytosis

    Directory of Open Access Journals (Sweden)

    Sarah Louise Gordon

    2016-02-01

    Full Text Available The reformation of synaptic vesicles during endocytosis is essential for the maintenance of neurotransmission in central nerve terminals. Newly formed synaptic vesicles must be generated with the correct protein cargo in the correct stoichiometry to be functional for exocytosis. Classical clathrin adaptor protein complexes play a key role in sorting and clustering synaptic vesicle cargo in this regard. However it is becoming increasingly apparent that additional fail-safe mechanisms exist to ensure the accurate retrieval of essential cargo molecules. For example, the monomeric adaptor proteins AP180/CALM and stonin-2 are required for the efficient retrieval of synaptobrevin II and synaptotagmin-1 respectively. Furthermore, recent studies have revealed that synaptobrevin II and synaptotagmin-1 interact with other synaptic vesicle cargoes to ensure a high fidelity of retrieval. These cargoes are synaptophysin (for synaptobrevin II and SV2A (for synaptotagmin-1. In this review we summarise current knowledge regarding the retrieval mechanisms for both synaptobrevin II and synaptotagmin-1 during endocytosis. We also define and set criteria for a new functional group of synaptic vesicle molecules that facilitate the retrieval of their interaction partners. We have termed these molecules intrinsic trafficking partners (iTRAPs and we discuss how the function of this group impacts on presynaptic performance in both health and disease.

  19. Pulsed eddy current inspection of CF-188 inner wing spar

    Science.gov (United States)

    Horan, Peter Francis

    Royal Canadian Air Force (RCAF) CF-188 Hornet aircraft engineering authorities have stated a requirement for a Non-Destructive Evaluation (NDE) technique to detect Stress Corrosion Cracking (SCC) in the inner wing spars without fastener or composite wing skin removal. Current radiographic inspections involve significant aircraft downtime, and Pulsed Eddy Current (PEC) inspection is proposed as a solution. The aluminum inner wing spars of CF-188 Hornet aircraft may undergo stress corrosion cracking (SCC) along the spar between the fasteners that secure carbon-fiber/ epoxy composite skin to the wing. Inspection of the spar through the wing skin is required to avoid wing disassembly. The thickness of the wing skin varies between 8 and 20 mm (0.3 to 0.8 inch) and fasteners may be either titanium or ferrous. PEC generated by a probe centered over a fastener, demonstrates capability of detecting simulated cracks within spars with the wing skin present. Comparison of signals from separate sensors, mounted to either side of the excitation coil, is used to detect differences in induced eddy current fields, which arise in the presence of cracks. To overcome variability in PEC signal response due to variation in 1) skin thickness, 2) fastener material and size, and 3) centering over fasteners, a large calibration data set is acquired. Multi-dimensional scores from a Modified Principal Components Analysis (PCA) of the data are reduced to one dimension (1D) using a Discriminant Analysis method. Under inspection conditions, calibrated PCA scores combined with discriminant analysis permit rapid real time go/no-go PEC detection of cracks in CF-188 inner wing spar. Probe designs using both pickup coils and Giant Magnetoresistive (GMR) sensors were tested on samples with the same ferrous and titanium fasteners found on the CF-188. Flaws were correctly detected at lift-offs of up to 21mm utilizing a variety of insulating skin materials simulating the carbon-fibre reinforced polymer

  20. ANNUAL RADIOACTIVE WASTE TANK INSPECTION PROGRAM 2010

    Energy Technology Data Exchange (ETDEWEB)

    West, B.; Waltz, R.

    2011-06-23

    Aqueous radioactive wastes from Savannah River Site (SRS) separations and vitrification processes are contained in large underground carbon steel tanks. Inspections made during 2010 to evaluate these vessels and other waste handling facilities along with evaluations based on data from previous inspections are the subject of this report. The 2010 inspection program revealed that the structural integrity and waste confinement capability of the Savannah River Site waste tanks were maintained. All inspections scheduled per SRR-LWE-2009-00138, HLW Tank Farm Inspection Plan for 2010, were completed. Ultrasonic measurements (UT) performed in 2010 met the requirements of C-ESG-00006, In-Service Inspection Program for High Level Waste Tanks, Rev. 3, and WSRC-TR-2002-00061, Rev.6. UT inspections were performed on Tanks 30, 31 and 32 and the findings are documented in SRNL-STI-2010-00533, Tank Inspection NDE Results for Fiscal Year 2010, Waste Tanks 30, 31 and 32. A total of 5824 photographs were made and 1087 visual and video inspections were performed during 2010. Ten new leaksites at Tank 5 were identified in 2010. The locations of these leaksites are documented in C-ESR-G-00003, SRS High Level Waste Tank Leaksite Information, Rev.5. Ten leaksites at Tank 5 were documented during tank wall/annulus cleaning activities. None of these new leaksites resulted in a release to the environment. The leaksites were documented during wall cleaning activities and the waste nodules associated with the leaksites were washed away. Previously documented leaksites were reactivated at Tank 12 during waste removal activities.

  1. Hanford site post NPH building inspection plan

    Energy Technology Data Exchange (ETDEWEB)

    Wagenblast, G.R., Westinghouse Hanford

    1996-09-12

    This plan establishes consistent post-NPH building inspection procedures and defines a procedure for prioritization of buildings for inspection to ensure the safety of facilities prior to reentry. Qualification of systems for restart of operation is not included. This plan takes advantage, where possible, of existing national procedures for post-NPH inspection of buildings, of existing structural design and evaluation documentation of Hanford facilities, and current and proposed seismic instrumentation located throughout the Hanford site. A list of buildings, prioritized according to current building safety function and building vulnerability (without regard for or information about a damaging natural forces event) is provided.

  2. A quantum extension to inspection game

    Science.gov (United States)

    Deng, Xinyang; Deng, Yong; Liu, Qi; Chang, Shuhua; Wang, Zhen

    2016-06-01

    Quantum game theory is a new interdisciplinary field between game theory and system engineering research. In this paper, we extend the classical inspection game into a quantum game version by quantizing the strategy space and importing entanglement between players. Our results show that the quantum inspection game has various Nash equilibria depending on the initial quantum state of the game. It is also shown that quantization can respectively help each player to increase his own payoff, yet fails to bring Pareto improvement for the collective payoff in the quantum inspection game.

  3. Risk-based methodology for USNRC inspections

    Energy Technology Data Exchange (ETDEWEB)

    Wong, S.M. [Brookhaven National Lab., Upton, NY (United States); Holahan, G.M.; Chung, J.W.; Johnson, M.R. [Nuclear Regulatory Commission, Washington, DC (United States). Office of Nuclear Reactor Regulation

    1995-12-01

    This paper describes the development and trial applications of a risk-based methodology to enhance the inspection processes for US nuclear power plants. Objectives of risk-based methods to complement prescriptive engineering approaches in US Nuclear Regulatory Commission (USNRC) inspection programs are presented. Insights from time-dependent risk profiles of plant configurational from Individual Plant Evaluation (IPE) studies were integrated to develop a framework for optimizing inspection efforts in NRC regulatory initiatives. Lessons learned from NRC pilot applications of the risk-based methodology for evaluation of the effectiveness of operational risk management programs at US nuclear power plant sites are also discussed.

  4. MRT fuel element inspection at Dounreay

    Energy Technology Data Exchange (ETDEWEB)

    Gibson, J.

    1997-08-01

    To ensure that their production and inspection processes are performed in an acceptable manner, ie. auditable and traceable, the MTR Fuel Element Fabrication Plant at Dounreay operates to a documented quality system. This quality system, together with the fuel element manufacturing and inspection operations, has been independently certified to ISO9002-1987, EN29002-1987 and BS5750:Pt2:1987 by Lloyd`s Register Quality Assurance Limited (LRQA). This certification also provides dual accreditation to the relevant German, Dutch and Australian certification bodies. This paper briefly describes the quality system, together with the various inspection stages involved in the manufacture of MTR fuel elements at Dounreay.

  5. Safety and Inspection Planning of Older Installations

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Ersdal, G.

    2008-01-01

    and a no-crack detection assumption imply that the inspection time intervals usually become longer and longer with time. For ageing platforms several small cracks should be expected to be observed according to the bath-tub curve development often assumed - implying an increased risk for crack initiation...... at the end of the expected lifetime - corresponding to a bath-tub hazard rate effect. The approach illustrated is for welded steel details in platforms. Systems effects are considered, including the use of dependence between inspection and failure events in different components for inspection planning....

  6. Autonomous Robotic Inspection in Tunnels

    Science.gov (United States)

    Protopapadakis, E.; Stentoumis, C.; Doulamis, N.; Doulamis, A.; Loupos, K.; Makantasis, K.; Kopsiaftis, G.; Amditis, A.

    2016-06-01

    In this paper, an automatic robotic inspector for tunnel assessment is presented. The proposed platform is able to autonomously navigate within the civil infrastructures, grab stereo images and process/analyse them, in order to identify defect types. At first, there is the crack detection via deep learning approaches. Then, a detailed 3D model of the cracked area is created, utilizing photogrammetric methods. Finally, a laser profiling of the tunnel's lining, for a narrow region close to detected crack is performed; allowing for the deduction of potential deformations. The robotic platform consists of an autonomous mobile vehicle; a crane arm, guided by the computer vision-based crack detector, carrying ultrasound sensors, the stereo cameras and the laser scanner. Visual inspection is based on convolutional neural networks, which support the creation of high-level discriminative features for complex non-linear pattern classification. Then, real-time 3D information is accurately calculated and the crack position and orientation is passed to the robotic platform. The entire system has been evaluated in railway and road tunnels, i.e. in Egnatia Highway and London underground infrastructure.

  7. RBI - Risk Based Inspection: new concept applied to management of FPSOs (Floating, Production and Storage Offshore) structural integrity; IBR-Inspecao baseada em risco: um novo conceito aplicado a gestao da integridade estrutural de FPSOs

    Energy Technology Data Exchange (ETDEWEB)

    Farias, Bruno de; Figueiredo, Eduardo; Luiz, Marcio [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil); Meurer, Gustavo; Duarte, Romulo; Belligotti, Rufo; Krzonkalla, Viviane [ABS Consulting, Rio de Janeiro, RJ (Brazil)

    2008-07-01

    Due to the difficulties of adapting the plan of inspection, typical of oil tankers, the units of the FPSO, began to occur large periods of unavailability of the cargo tanks. Also, with the expansion of the fleet, began to notice a difficulty in meeting the plan of inspection of the FPSO's hull. To improve the management of structural integrity of its FPSO's, PETROBRAS aims to ABS Consulting with the development and implementation of Risk-Based Inspection, known as RBI. This concept is applicable to various branches of industry. The companies began their implementation of oil by refineries. The development application for a ship's hull is recent and PETROBRAS is one of the first companies to implement the IBR for monitoring of the FPSO hull. (author)

  8. Electrostatic assembly/disassembly of nanoscaled colloidosomes for light-triggered cargo release

    KAUST Repository

    Li, Song

    2015-04-27

    Colloidosome capsules possess the potential for the encapsulation and release of molecular and macromolecular cargos. However, the stabilization of the colloidosome shell usually requires an additional covalent crosslinking which irreversibly seals the capsules, and greatly limits their applications in large-cargos release. Herein we report nanoscaled colloidosomes designed by the electrostatic assembly of organosilica nanoparticles (NPs) with oppositely charged surfaces (rather than covalent bonds), arising from different contents of a bridged nitrophenylene-alkoxysilane [NB; 3-nitro-N-(3-(triethoxysilyl)propyl)-4-(((3-(triethoxysilyl)propyl)-amino)methyl)benzamid] derivative in the silica. The surface charge of the positively charged NPs was reversed by light irradiation because of a photoreaction in the NB moieties, which impacted the electrostatic interactions between NPs and disassembled the colloidosome nanosystems. This design was successfully applied for the encapsulation and light-triggered release of cargos. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Binding to any ESCRT can mediate ubiquitin-independent cargo sorting

    Science.gov (United States)

    Mageswaran, Shrawan Kumar; Dixon, Megan Gorringe; Curtiss, Matt; Keener, James P.; Babst, Markus

    2013-01-01

    The ESCRT machinery is known to sort ubiquitinated transmembrane proteins into vesicles that bud into the lumen of multivesicular bodies (MVBs). Although the ESCRTs themselves are ubiquitinated they are excluded from the intraluminal vesicles and recycle back to the cytoplasm for further rounds of sorting. To obtain insights into the rules that distinguish ESCRT machinery from cargo we analyzed the trafficking of artificial ESCRT-like protein fusions. These studies showed that lowering ESCRT-binding affinity converts a protein from behaving like ESCRT machinery into cargo of the MVB pathway, highlighting the close relationship between machinery and the cargoes they sort. Furthermore, our findings give insights into the targeting of soluble proteins into the MVB pathway and show that binding to any of the ESCRTs can mediate ubiquitin-independent MVB sorting. PMID:24148098

  10. Dry bulk cargo shipping - An overlooked threat to the marine environment?

    Science.gov (United States)

    Grote, Matthias; Mazurek, Nicole; Gräbsch, Carolin; Zeilinger, Jana; Le Floch, Stéphane; Wahrendorf, Dierk-Steffen; Höfer, Thomas

    2016-09-15

    Approximately 9.5billiontonnes of goods is transported over the world oceans annually with dry bulk representing the largest cargo group. This paper aims to analyse whether the transport and associated inputs of dry bulks into the sea create a risk for the marine environment. For this purpose, we analyse the international regulatory background concerning environmental protection (MARPOL), estimate quantities and identify inputs of such cargoes into the oceans (accidental and operational), and use available information for hazard assessment. Annually, more than 2.15milliontonnes of dry bulk cargoes are likely to enter the oceans, of which 100,000tonnes are potentially harmful to the marine environment according to the definition included in draft maritime regulation. The assessment of the threat to the marine environment is hampered by a lack of available information on chemical composition, bioavailability and toxicity. Perspectives for amendments of the unsatisfying pollution prevention regulations are discussed.

  11. Mechanized azobenzene-functionalized zirconium metal-organic framework for on-command cargo release

    Science.gov (United States)

    Meng, Xiangshi; Gui, Bo; Yuan, Daqiang; Zeller, Matthias; Wang, Cheng

    2016-01-01

    Stimuli-responsive metal-organic frameworks (MOFs) have gained increasing attention recently for their potential applications in many areas. We report the design and synthesis of a water-stable zirconium MOF (Zr-MOF) that bears photoresponsive azobenzene groups. This particular MOF can be used as a reservoir for storage of cargo in water, and the cargo-loaded MOF can be further capped to construct a mechanized MOF through the binding of β-cyclodextrin with the azobenzene stalks on the MOF surface. The resulting mechanized MOF has shown on-command cargo release triggered by ultraviolet irradiation or addition of competitive agents without premature release. This study represents a simple approach to the construction of stimuli-responsive mechanized MOFs, and considering mechanized UiO-68-azo made from biocompatible components, this smart system may provide a unique MOF platform for on-command drug delivery in the future. PMID:27493996

  12. Solar-electric-propulsion cargo vehicles for split/sprint Mars mission

    Science.gov (United States)

    Callaghan, Christopher E.; Crowe, Michael D.; Swis, Matthew J.; Mickney, Marcus R.; Montgomery, C. Keith; Walters, Robert; Thoden, Scott

    1991-01-01

    In support of the proposed exploration of Mars, an unmanned cargo ferry SEMM1 (Solar Electric Mars Mission) was designed. The vehicle is based on solar electric propulsion, and required to transport a cargo of 61,000 kg. The trajectory is a combination of spirals; first, out from LEO, then around the sun, then spiral down to low Mars orbit. The spacecraft produces 3.03 MWe power using photovoltaic flexible blanket arrays. Ion thrusters using argon as a propellant were selected to drive the ship, providing about 60 Newtons of thrust in low Earth orbit. The configuration is based on two long truss beams to which the 24 individual, self-deployable, solar arrays are attached. The main body module supports the two beams and houses the computers, electrical, and control equipment. The thruster module is attached to the rear of the main body, and the cargo to the front.

  13. Program for establishing long-time flight service performance of composite materials in the center wing structure of C-130 aircraft. Phase 5: flight service and inspection. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kizer, J.A.

    1981-10-01

    Inspections of the C-130 composite-reinforced center wings were conducted over the flight service monitoring period of more than six years. Twelve inspections were conducted on each of the two C-130H airplanes having composite reinforced center wing boxes. Each inspection consisted of visual and ultrasonic inspection of the selective boron-epoxy reinforced center wings which included the inspection of the boron-epoxy laminates and the boron-epoxy reinforcement/aluminum structure adhesive bondlines. During the flight service monitoring period, the two C-130H aircraft accumulated more than 10,000 flight hours and no defects were detected in the inspections over this period. The successful performance of the C-130H aircraft with composite-reinforced center wings allowed the transfer of the responsibilities of inspecting and maintaining these two aircraft to the U. S. Air Force.

  14. Optimal inspection Strategies for Offshore Structural Systems

    DEFF Research Database (Denmark)

    Faber, M. H.; Sørensen, John Dalsgaard; Kroon, I. B.

    1992-01-01

    Optimal planning of inspection and maintenance strategies for structures has become a subject of increasing interest especially for offshore structures for which large costs are associated with structural failure, inspections and repairs. During the last five years a methodology has been formulated...... a mathematical framework for the estimation of the failure and repair costs a.ssociated with systems failure. Further a strategy for selecting the components to inspect based on decision tree analysis is suggested. Methods and analysis schemes are illustrated by a simple example....... to perform optimal inspection and repair strategies for structural components subject to uncertain loading conditions and material behavior. In this paper this methodology is extended to inelude also system failure i.e. failure of a given sub set of all the structural components. This extension ineludes...

  15. 7 CFR 46.40 - Inspection service.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE MARKETING OF PERISHABLE AGRICULTURAL COMMODITIES REGULATIONS (OTHER THAN RULES OF PRACTICE) UNDER THE PERISHABLE AGRICULTURAL COMMODITIES ACT, 1930 Commodity...

  16. Emerging nondestructive inspection methods for aging aircraft

    Energy Technology Data Exchange (ETDEWEB)

    Beattie, A; Dahlke, L; Gieske, J [and others

    1994-01-01

    This report identifies and describes emerging nondestructive inspection (NDI) methods that can potentially be used to inspect commercial transport and commuter aircraft for structural damage. The nine categories of emerging NDI techniques are: acoustic emission, x-ray computed tomography, backscatter radiation, reverse geometry x-ray, advanced electromagnetics, including magnetooptic imaging and advanced eddy current techniques, coherent optics, advanced ultrasonics, advanced visual, and infrared thermography. The physical principles, generalized performance characteristics, and typical applications associated with each method are described. In addition, aircraft inspection applications are discussed along with the associated technical considerations. Finally, the status of each technique is presented, with a discussion on when it may be available for use in actual aircraft maintenance programs. It should be noted that this is a companion document to DOT/FAA/CT-91/5, Current Nondestructive Inspection Methods for Aging Aircraft.

  17. An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor

    Science.gov (United States)

    Dagdas, Yasin F; Belhaj, Khaoula; Maqbool, Abbas; Chaparro-Garcia, Angela; Pandey, Pooja; Petre, Benjamin; Tabassum, Nadra; Cruz-Mireles, Neftaly; Hughes, Richard K; Sklenar, Jan; Win, Joe; Menke, Frank; Findlay, Kim; Banfield, Mark J; Kamoun, Sophien; Bozkurt, Tolga O

    2016-01-01

    Plants use autophagy to safeguard against infectious diseases. However, how plant pathogens interfere with autophagy-related processes is unknown. Here, we show that PexRD54, an effector from the Irish potato famine pathogen Phytophthora infestans, binds host autophagy protein ATG8CL to stimulate autophagosome formation. PexRD54 depletes the autophagy cargo receptor Joka2 out of ATG8CL complexes and interferes with Joka2's positive effect on pathogen defense. Thus, a plant pathogen effector has evolved to antagonize a host autophagy cargo receptor to counteract host defenses. DOI: http://dx.doi.org/10.7554/eLife.10856.001 PMID:26765567

  18. Design and development of a focusing electromagnet for RF linac of a cargo scanner

    Energy Technology Data Exchange (ETDEWEB)

    Nayak, B., E-mail: biswaranjan.nayak1@gmail.com; Acharya, S.; Bhattacharjee, D.; Chandan, Shiv; Choudhury, N.; Sharma, V.; Mittal, K.C.; Gantayet, L.M.

    2014-11-11

    Cargo scanning of contraband objects by high energetic X-rays requires compact and self-contained RF linacs. To achieve this goal, a 6 MeV, 700 W standing wave RF electron linac has been developed at Accelerator and Pulse Power Division, BARC. To obtain the image of scanned objects with good resolution requires a focused electron beam at the target. This paper presents the design, development and integration of a solenoid magnet with a compact RF linac and its performance with electron beam for cargo scanning applications.

  19. Enabling a viable technique for the optimization of LNG carrier cargo operations

    Science.gov (United States)

    Alaba, Onakoya Rasheed; Nwaoha, T. C.; Okwu, M. O.

    2016-09-01

    In this study, we optimize the loading and discharging operations of the Liquefied Natural Gas (LNG) carrier. First, we identify the required precautions for LNG carrier cargo operations. Next, we prioritize these precautions using the analytic hierarchy process (AHP) and experts' judgments, in order to optimize the operational loading and discharging exercises of the LNG carrier, prevent system failure and human error, and reduce the risk of marine accidents. Thus, the objective of our study is to increase the level of safety during cargo operations.

  20. Enabling a Viable Technique for the Optimization of LNG Carrier Cargo Operations

    Institute of Scientific and Technical Information of China (English)

    Onakoya Rasheed Alaba; T C Nwaoha; M O Okwu

    2016-01-01

    In this study, we optimize the loading and discharging operations of the Liquefied Natural Gas (LNG) carrier. First, we identify the required precautions for LNG carrier cargo operations. Next, we prioritize these precautions using the analytic hierarchy process (AHP) and experts’ judgments, in order to optimize the operational loading and discharging exercises of the LNG carrier, prevent system failure and human error, and reduce the risk of marine accidents. Thus, the objective of our study is to increase the level of safety during cargo operations.