WorldWideScience

Sample records for agricultural biotechnology

  1. Agriculture biotechnology report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report provides the basis for an overall agriculture biotechnology strategy for Saskatchewan, encompassing all aspects of the biotechnology sector and supporting institutions. It presents results of a survey of over 70 industry and public sector leaders in agriculture biotechnology in order to assist Saskatchewan Agriculture & Food in defining its role and involvement in the agriculture biotechnology industry. Issues examined include: Goals for the agriculture biotechnology industry; research and development; technology transfer and commercialisation; infrastructure and services; human resources; legislation and policy; funding; future core areas of research and development; and the role of government in developing the industry. The report concludes with lists of recommendations. The supplement lists the survey questions and responses.

  2. "Othering" agricultural biotechnology: Slovenian media representation of agricultural biotechnology.

    Science.gov (United States)

    Zajc, Jožica; Erjavec, Karmen

    2014-08-01

    While studies on media representations of agricultural biotechnology mostly analyse media texts, this work is intended to fill a research gap with an analysis of journalistic interpretations of media representations. The purpose of this project was to determine how news media represent agricultural biotechnology and how journalists interpret their own representations. A content and critical discourse analysis of news texts published in the Slovenian media over two years and in-depth interviews with their authors were conducted. News texts results suggest that most of the news posts were "othering" biotechnology and biotechnologists: biotechnology as a science and individual scientists are represented as "they," who are socially irresponsible, ignorant, arrogant, and "our" enemies who produce unnatural processes and work for biotechnology companies, whose greed is destroying people, animals, and the environment. Most journalists consider these representations to be objective because they have published the biotechnologists' opinions, despite their own negative attitudes towards biotechnology.

  3. The costly benefits of opposing agricultural biotechnology.

    Science.gov (United States)

    Apel, Andrew

    2010-11-30

    Rigorous application of a simple definition of what constitutes opposition to agricultural biotechnology readily encompasses a wide array of key players in national and international systems of food production, distribution and governance. Even though the sum of political and financial benefits of opposing agricultural biotechnology appears vastly to outweigh the benefits which accrue to providers of agricultural biotechnology, technology providers actually benefit from this opposition. If these barriers to biotechnology were removed, subsistence farmers still would not represent a lucrative market for improved seed. The sum of all interests involved ensures that subsistence farmers are systematically denied access to agricultural biotechnology.

  4. Agricultural Biotechnology Research and Development in Hunan

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Recent agricultural biotechnology research and advances in the province are reviewed. Targets and practices for biotechnological development in depth are discussed, with stress on the talent's training, new techniques' establishment and its industrialization, starting from the existing level and problems in the field in the province.

  5. Emerging Agricultural Biotechnologies for Sustainable Agriculture and Food Security.

    Science.gov (United States)

    Anderson, Jennifer A; Gipmans, Martijn; Hurst, Susan; Layton, Raymond; Nehra, Narender; Pickett, John; Shah, Dilip M; Souza, Thiago Lívio P O; Tripathi, Leena

    2016-01-20

    As global populations continue to increase, agricultural productivity will be challenged to keep pace without overtaxing important environmental resources. A dynamic and integrated approach will be required to solve global food insecurity and position agriculture on a trajectory toward sustainability. Genetically modified (GM) crops enhanced through modern biotechnology represent an important set of tools that can promote sustainable agriculture and improve food security. Several emerging biotechnology approaches were discussed in a recent symposium organized at the 13th IUPAC International Congress of Pesticide Chemistry meeting in San Francisco, CA, USA. This paper summarizes the innovative research and several of the new and emerging technologies within the field of agricultural biotechnology that were presented during the symposium. This discussion highlights how agricultural biotechnology fits within the context of sustainable agriculture and improved food security and can be used in support of further development and adoption of beneficial GM crops.

  6. Design for values in agricultural biotechnology

    NARCIS (Netherlands)

    Belt, van den Henk

    2015-01-01

    Agricultural biotechnology dates from the last two decades of the twentieth century. It involves the creation of plants and animals with new useful traits by inserting one or more genes taken from other species. New legal possibilities for patenting transgenic organisms and isolated genes have be

  7. BIOTECHNOLOGY – SCIENCE AND SECTOR OF AGRICULTURE

    Directory of Open Access Journals (Sweden)

    Doroshenko N. P.

    2016-02-01

    Full Text Available This article presents information about the features of biotechnology as the driving force of scientific and technological progress. The national programs of the leading countries of the world, it is one of the priority sectors, reflecting the level of the socio-economic condition of the society. Biotechnology is now successfully solves such vital tasks as providing food, the establishment of effective medicaments, obtaining fuel based on renewable raw materials, maintaining ecological balance, conservation of biological resources of the Earth. The development of agriculture in modern conditions is impossible without agricultural biotechnology. It is directly related to viticulture. Choosing an object of an integrated system (embryos, apical meristem, axillary buds, it is possible to clone plants, i.e. produce plants identical to the original. If the same as the object to use isolated cells or protoplasts, in this case, there will most likely altered versions, creating diversity for the breeder. Genetic engineering – the science of younger, since the establishment of the first chimeric DNA molecule. The origin of genetic engineering is rooted in the development of molecular genetics, biochemistry. These technologies, undoubtedly progressive, but their biological safety is still insufficiently explored and is a danger to all life on Earth. The leading Western powers carried out strict control over the introduction of transgenic crop plants, as they are in agrocenosis new biological risks that may adversely affect the plants, animals and humans. In Russia, as in other countries, have already adopted the law “State regulation of genetic engineering”

  8. Current and Future Leaders' Perceptions of Agricultural Biotechnology

    Science.gov (United States)

    Wingenbach, Gary J.; Miller, Rene P.

    2009-01-01

    Were elected state FFA officers' attitudes toward agricultural biotechnology significantly different from elected Texas legislators' attitudes about the same topic? The purpose of this study was to determine if differences existed in agricultural biotechnology perceptions or information source preferences when compared by leadership status:…

  9. Students' knowledge of, and attitudes towards biotechnology revisited, 1995-2014: Changes in agriculture biotechnology but not in medical biotechnology.

    Science.gov (United States)

    Chen, Shao-Yen; Chu, Yih-Ru; Lin, Chen-Yung; Chiang, Tzen-Yuh

    2016-09-10

    Modern biotechnology is one of the most important scientific and technological revolutions in the 21st century, with an increasing and measurable impact on society. Development of biotechnology curriculum has become important to high school bioscience classrooms. This study has monitored high school students in Taiwan on their knowledge of and attitudes towards biotechnology for nearly two decades. Not surprisingly, knowledge of biotechnology of current students has increased significantly (p biotechnology. There was a positive correlation between biotechnology knowledge and attitudes toward biotechnology for current students who study Advanced Biology (AB). However, for current students who did not study AB, there was a negative correlation.The attitude results showed that students today expressed less favorable opinions toward agricultural biotechnology (p medical biotechnology. In addition, current students showed a greater concern involving environmental risks than former students. Interestingly, the high school curriculum did affect students' attitudes toward genetically engineered (GE) plants but not GE animals. Our current study also found that the students' attitude towards GE animals was influenced more by their limited knowledge than by their moral belief. On the basis of findings from this study, we suggest that more materials of emerging animal biotechnology should be included in high school curriculum and recommend that high school teachers and university faculty establish a collaborative framework in the near future. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(5):475-491, 2016.

  10. BIOTECHNOLOGY – SCIENCE AND SECTOR OF AGRICULTURE

    OpenAIRE

    Doroshenko N. P.; Troshin L. P.; Alzubaidi K. K.

    2016-01-01

    This article presents information about the features of biotechnology as the driving force of scientific and technological progress. The national programs of the leading countries of the world, it is one of the priority sectors, reflecting the level of the socio-economic condition of the society. Biotechnology is now successfully solves such vital tasks as providing food, the establishment of effective medicaments, obtaining fuel based on renewable raw materials, maintaining ecological balanc...

  11. 78 FR 7387 - Advisory Committee on Biotechnology and 21st Century Agriculture; Renewal

    Science.gov (United States)

    2013-02-01

    ...; ] DEPARTMENT OF AGRICULTURE Advisory Committee on Biotechnology and 21st Century Agriculture; Renewal AGENCY: Agricultural Research Service, USDA. ACTION: Advisory Committee on Biotechnology and 21st Century Agriculture... Committee on Biotechnology and 21st Century Agriculture (AC21). The Secretary of Agriculture has...

  12. Biotechnology: An Assessment of Agricultural Science Teachers' Knowledge and Attitudes

    Science.gov (United States)

    Mowen, Diana L.; Roberts, T. Grady; Wingenbach, Gary J.; Harlin, Julie F.

    2007-01-01

    The purpose of this study was to explore agricultural science teachers' knowledge levels and attitudes toward biotechnology topics. The average agricultural science teacher in this study was a 37-year-old male who had taught for 12 years. He had a bachelor's degree and had lived or worked on a farm or ranch. He had not attended…

  13. Agricultural biotechnology and its contribution to the global knowledge economy.

    Science.gov (United States)

    Aerni, Philipp

    2007-01-01

    The theory of neoclassical welfare economics largely shaped international and national agricultural policies during the Cold War period. It treated technology as an exogenous factor that could boost agricultural productivity but not necessarily sustainable agriculture. New growth theory, the economic theory of the new knowledge economy, treats technological change as endogenous and argues that intangible assets such as human capital and knowledge are the drivers of sustainable economic development. In this context, the combined use of agricultural biotechnology and information technology has a great potential, not just to boost economic growth but also to empower people in developing countries and improve the sustainable management of natural resources. This article outlines the major ideas behind new growth theory and explains why agricultural economists and agricultural policy-makers still tend to stick to old welfare economics. Finally, the article uses the case of the Cassava Biotechnology Network (CBN) to illustrate an example of how new growth theory can be applied in the fight against poverty. CBN is a successful interdisciplinary crop research network that makes use of the new knowledge economy to produce new goods that empower the poor and improve the productivity and nutritional quality of cassava. It shows that the potential benefits of agricultural biotechnology go far beyond the already known productivity increases and pesticide use reductions of existing GM crops.

  14. The role of biotechnology for agricultural sustainability in Africa

    OpenAIRE

    2007-01-01

    Sub-Saharan Africa could have a shortfall of nearly 90 Mt of cereals by the year 2025 if current agricultural practices are maintained. Biotechnology is one of the ways to improve agricultural production. Insect-resistant varieties of maize and cotton suitable for the subcontinent have been identified as already having a significant impact. Virus-resistant crops are under development. These include maize resistant to the African endemic maize streak virus and cassava resistant to African cass...

  15. 76 FR 48797 - Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture Meeting

    Science.gov (United States)

    2011-08-09

    ... Agricultural Research Service Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture... on Biotechnology and 21st Century Agriculture (AC21). DATES: August 30-31, 2011. ADDRESSES: Rooms... consists of members representing the biotechnology industry, the organic food industry, farming...

  16. 77 FR 26725 - Advisory Committee on Biotechnology and 21st Century Agriculture Meeting

    Science.gov (United States)

    2012-05-07

    ...; ] DEPARTMENT OF AGRICULTURE Advisory Committee on Biotechnology and 21st Century Agriculture Meeting AGENCY... Biotechnology and 21st Century Agriculture (AC21). DATES: The meeting dates are May 29-30, 2012, 8:30 a.m. to 5... consists of members representing the biotechnology industry, the organic food industry, farming...

  17. 77 FR 46681 - Advisory Committee on Biotechnology and 21st Century Agriculture; Notice of Meeting

    Science.gov (United States)

    2012-08-06

    ...; ] DEPARTMENT OF AGRICULTURE Advisory Committee on Biotechnology and 21st Century Agriculture; Notice of Meeting... meeting of the Advisory Committee on Biotechnology and 21st Century Agriculture (AC21). DATES: The meeting... the biotechnology industry, the organic food industry, farming communities, the seed industry,...

  18. 76 FR 3599 - Renewal of the Advisory Committee on Biotechnology and 21st Century Agriculture

    Science.gov (United States)

    2011-01-20

    ...; ] DEPARTMENT OF AGRICULTURE Agricultural Research Service Renewal of the Advisory Committee on Biotechnology... Biotechnology and 21st Century Agriculture (AC21) for a 2- year period. FOR FURTHER INFORMATION CONTACT... Committee Purpose: USDA supports the responsible development and application of biotechnology within...

  19. 77 FR 11064 - Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture Meeting

    Science.gov (United States)

    2012-02-24

    ... Agricultural Research Service Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture... Committee on Biotechnology and 21st Century Agriculture (AC21). DATES: The meeting dates are March 5-6, 2012..., 2012. The AC21 consists of members representing the biotechnology industry, the organic food...

  20. Plant biotechnology patents: applications in agriculture and medicine.

    Science.gov (United States)

    Hefferon, Kathleen

    2010-06-01

    Recent advances in agricultural biotechnology have enabled the field of plant biology to move forward in great leaps and bounds. In particular, recent breakthroughs in molecular biology, plant genomics and crop science have brought about a paradigm shift of thought regarding the manner by which plants can be utilized both in agriculture and in medicine. Besides the more well known improvements in agronomic traits of crops such as disease resistance and drought tolerance, plants can now be associated with topics as diverse as biofuel production, phytoremediation, the improvement of nutritional qualities in edible plants, the identification of compounds for medicinal purposes in plants and the use of plants as therapeutic protein production platforms. This diversification of plant science has been accompanied by the great abundance of new patents issued in these fields and, as many of these inventions approach commercial realization, the subsequent increase in agriculturally-based industries. While this review chapter is written primarily for plant scientists who have great interest in the new directions being taken with respect to applications in agricultural biotechnology, those in other disciplines, such as medical researchers, environmental scientists and engineers, may find significant value in reading this article as well. The review attempts to provide an overview of the most recent patents issued for plant biotechnology with respect to both agriculture and medicine. The chapter concludes with the proposal that the combined driving forces of climate change, as well as the ever increasing needs for clean energy and food security will play a pivotal role in leading the direction for applied plant biotechnology research in the future.

  1. The integrated web service and genome database for agricultural plants with biotechnology information

    Science.gov (United States)

    Kim, ChangKug; Park, DongSuk; Seol, YoungJoo; Hahn, JangHo

    2011-01-01

    The National Agricultural Biotechnology Information Center (NABIC) constructed an agricultural biology-based infrastructure and developed a Web based relational database for agricultural plants with biotechnology information. The NABIC has concentrated on functional genomics of major agricultural plants, building an integrated biotechnology database for agro-biotech information that focuses on genomics of major agricultural resources. This genome database provides annotated genome information from 1,039,823 records mapped to rice, Arabidopsis, and Chinese cabbage. PMID:21887015

  2. Transgenic barley: a prospective tool for biotechnology and agriculture.

    Science.gov (United States)

    Mrízová, Katarína; Holasková, Edita; Öz, M Tufan; Jiskrová, Eva; Frébort, Ivo; Galuszka, Petr

    2014-01-01

    Barley (Hordeum vulgare L.) is one of the founder crops of agriculture, and today it is the fourth most important cereal grain worldwide. Barley is used as malt in brewing and distilling industry, as an additive for animal feed, and as a component of various food and bread for human consumption. Progress in stable genetic transformation of barley ensures a potential for improvement of its agronomic performance or use of barley in various biotechnological and industrial applications. Recently, barley grain has been successfully used in molecular farming as a promising bioreactor adapted for production of human therapeutic proteins or animal vaccines. In addition to development of reliable transformation technologies, an extensive amount of various barley genetic resources and tools such as sequence data, microarrays, genetic maps, and databases has been generated. Current status on barley transformation technologies including gene transfer techniques, targets, and progeny stabilization, recent trials for improvement of agricultural traits and performance of barley, especially in relation to increased biotic and abiotic stress tolerance, and potential use of barley grain as a protein production platform have been reviewed in this study. Overall, barley represents a promising tool for both agricultural and biotechnological transgenic approaches, and is considered an ancient but rediscovered crop as a model industrial platform for molecular farming.

  3. The role of biotechnology for agricultural sustainability in Africa.

    Science.gov (United States)

    Thomson, Jennifer A

    2008-02-27

    Sub-Saharan Africa could have a shortfall of nearly 90Mt of cereals by the year 2025 if current agricultural practices are maintained. Biotechnology is one of the ways to improve agricultural production. Insect-resistant varieties of maize and cotton suitable for the subcontinent have been identified as already having a significant impact. Virus-resistant crops are under development. These include maize resistant to the African endemic maize streak virus and cassava resistant to African cassava mosaic virus. Parasitic weeds such as Striga attack the roots of crops such as maize, millet, sorghum and upland rice. Field trials in Kenya using a variety of maize resistant to a herbicide have proven very successful. Drought-tolerant crops are also under development as are improved varieties of local African crops such as bananas, cassava, sorghum and sweet potatoes.

  4. 77 FR 48948 - Notice of the Advisory Committee on Biotechnology and 21st Century Agriculture Meeting; Correction

    Science.gov (United States)

    2012-08-15

    ...; ] DEPARTMENT OF AGRICULTURE Agricultural Research Service Notice of the Advisory Committee on Biotechnology and... meeting of the Advisory Committee on Biotechnology and 21st Century Agriculture (AC21). The notice...

  5. Agricultural biotechnology and smallholder farmers in developing countries.

    Science.gov (United States)

    Anthony, Vivienne M; Ferroni, Marco

    2012-04-01

    Agricultural biotechnology holds much potential to contribute towards crop productivity gains and crop improvement for smallholder farmers in developing countries. Over 14 million smallholder farmers are already benefiting from biotech crops such as cotton and maize in China, India and other Asian, African and Central/South American countries. Molecular breeding can accelerate crop improvement timescales and enable greater use of diversity of gene sources. Little impact has been realized to date with fruits and vegetables because of development timescales for molecular breeding and development and regulatory costs and political considerations facing biotech crops in many countries. Constraints to the development and adoption of technology-based solutions to reduce yield gaps need to be overcome. Full integration with broader commercial considerations such as farmer access to seed distribution systems that facilitate dissemination of improved varieties and functioning markets for produce are critical for the benefits of agricultural biotechnology to be fully realized by smallholders. Public-private partnerships offer opportunities to catalyze new approaches and investment while accelerating integrated research and development and commercial supply chain-based solutions.

  6. Reducing agricultural greenhouse gas emissions: role of biotechnology, organic systems, and consumer behavior

    Science.gov (United States)

    All agricultural systems have environmental and societal costs and benefits that should be objectively quantified before recommending specific management practices. Agricultural biotechnology, which takes advantage of genetically engineered organisms (GEOs), along with organic cropping systems, econ...

  7. IMPACT OF AGRICULTURAL BIOTECHNOLOGY ON ENVIRONMENT AND FOOD SECURITY

    Directory of Open Access Journals (Sweden)

    Marijan Jošt

    2003-12-01

    Full Text Available The application of modern biotechnology in agricultural production processes has generated new ethical, economic, social and environmental dilemmas confronting scientists all over the world. While current knowledge is insufficient for assessing the promised benefits and possible risks of genetically modified organisms (GMOs, the principle of “substantial equivalence” in comparing GM and conventional food is profoundly flawed and scientifically insupportable. The current generation of GMOs provide small benefits except corporate profit and marginally improved grower returns. The TRIPS agreement has allowed worldwide patenting of genes and microorganisms, as well as genetically engineered organisms. Granting patents on life encourages biopiracy and the theft of genetic resources belonging to the local community. At the same time, the patented products are sold at relatively high prices to developing countries – the same countries from which the product originated.

  8. 76 FR 14895 - Request for Nominations to the Advisory Committee on Biotechnology and 21st Century Agriculture

    Science.gov (United States)

    2011-03-18

    ... Agricultural Research Service Request for Nominations to the Advisory Committee on Biotechnology and 21st...: Notice of request for nominations to the Advisory Committee on Biotechnology and 21st Century Agriculture... the Advisory Committee on Biotechnology and 21st Century Agriculture (AC21). DATES:...

  9. The Sociology of Agriculture in Transition: The Political Economy of Agriculture after Biotechnology

    Directory of Open Access Journals (Sweden)

    Gabriela Pechlaner

    2010-01-01

    Full Text Available In 2007, a global food crisis brought the topic of agriculture back into the public eye, and retriggered debates about the ability of agricultural industrialization to feed the world. As a nature-based process and an exception to capitalist industrialization, agriculture trends are difficult to assess. One of the more productive attempts to do so has developed conceptual tools that account for the distinction from typical capital accumulation patterns, notably Goodman,Sorj, and Wilkinson’s (1987 classic concepts of “appropriationism” and “substitutionism.” Agricultural biotechnologies are testing the limits of even these more refined conceptualizations, as the technologies’ associated proprietary framework — including seed saving restrictions, grower contracts, and patent infringement litigation — is reorganizing many traditional agricultural practices. Drawing on case studies in Mississippi, U.S. and Saskatchewan, Canada, thispaper argues that these trends suggest a need for a new concept in political economy of agriculture theory, which I term "expropriationism.” This concept identifies several aspects of an agricultural reorganization premised on legal means to enhance capital accumulation and on separating corporate ownership from liability. This accumulation strategy has important implications given the highsalience that agriculture has for society.

  10. Students' Knowledge of, and Attitudes towards Biotechnology Revisited, 1995-2014: Changes in Agriculture Biotechnology but Not in Medical Biotechnology

    Science.gov (United States)

    Chen, Shao-Yen; Chu, Yih-Ru; Lin, Chen-Yung; Chiang, Tzen-Yuh

    2016-01-01

    Modern biotechnology is one of the most important scientific and technological revolutions in the 21st century, with an increasing and measurable impact on society. Development of biotechnology curriculum has become important to high school bioscience classrooms. This study has monitored high school students in Taiwan on their knowledge of and…

  11. [Ecological significance of arbuscular mycorrhiza biotechnology in modern agricultural system].

    Science.gov (United States)

    Zhang, Yong; Zeng, Ming; Xiong, Bingquan; Yang, Xiaohong

    2003-04-01

    Mycorrhiza plays a key role in nutrient cycling in ecosystem, and protects host plant against environmental stress. Under natural condition, plant's mycorrhizal structure is a normal phenomenon, and arbuscular mycorrhiza (AM) association is the commonest mycorrhizal type. If well mycorrhizal structure can be formed during plant root system developing process, the quantity and quality of plant production will be improved in large. Because of its effects on plant growth and health, it is accepted that AM symbiosis can reduce chemical fertilizer and pesticide inputs. Consequently, this will lead to a reduction in harmful chemical substance impact on environment. The key effects of AM symbiosis can be summarized as follows: (1) improving rooting and plant establishment; (2) improving uptake of low mobile ions; (3) improving nutrient cycling; (4) enhancing plant tolerance to (biotic and abiotic) stress; (5) improving quality of soil structure; and (6) enhancing plant community diversity. In this paper, the ecological characteristic of arbuscular mycorrhiza fungi (AMF), effects of AM on host plant, and ecologic significance of AM biotechnology in agricultural system were reviewed.

  12. Ethical Tools to Support Systematic Public Deliberations about the Ethical Aspects of Agricultural Biotechnologies

    NARCIS (Netherlands)

    Beekman, V.; Brom, F.W.A.

    2007-01-01

    This special issue of the Journal of Agricultural and Environmental Ethics presents so-called ethical tools that are developed to support systematic public deliberations about the ethical aspects of agricultural biotechnologies. This paper firstly clarifies the intended connotations of the term ¿eth

  13. Agricultural Science Teachers' Barriers, Roles, and Information Source Preferences for Teaching Biotechnology Topics

    Science.gov (United States)

    Mowen, Diana L.; Wingenbach, Gary J.; Roberts, T. Grady; Harlin, Julie F.

    2007-01-01

    The purpose of this study was to determine barriers, roles, and information source preferences for teaching agricultural biotechnology topics. Agricultural science teachers were described primarily as 37 year-old males who had taught for 12 years, had bachelor's degrees, and had lived or worked on a farm or ranch. Equipment was perceived as the…

  14. The impacts and acceptance of agricultural biotechnology: an introduction to the special issue

    NARCIS (Netherlands)

    Zilberman, D.; Wesseler, J.H.H.

    2014-01-01

    Attitudes towards and acceptance of agricultural biotechnology, which involves inserting genes that carry new traits into existing varieties, has been subject to much debate. This special issue aims to address several gaps in the literature on genetically modified (GM) technology in agriculture. Som

  15. College Students' View of Biotechnology Products and Practices in Sustainable Agriculture Systems

    Science.gov (United States)

    Anderson, William A.

    2008-01-01

    Sustainable agriculture implies the use of products and practices that sustain production, protect the environment, ensure economic viability, and maintain rural community viability. Disagreement exists as to whether or not the products and practices of modern biotechnological support agricultural sustainability. The purpose of this study was to…

  16. Biotechnologies for the management of genetic resources for food and agriculture.

    Science.gov (United States)

    Lidder, Preetmoninder; Sonnino, Andrea

    2012-01-01

    In recent years, the land area under agriculture has declined as also has the rate of growth in agricultural productivity while the demand for food continues to escalate. The world population now stands at 7 billion and is expected to reach 9 billion in 2045. A broad range of agricultural genetic diversity needs to be available and utilized in order to feed this growing population. Climate change is an added threat to biodiversity that will significantly impact genetic resources for food and agriculture (GRFA) and food production. There is no simple, all-encompassing solution to the challenges of increasing productivity while conserving genetic diversity. Sustainable management of GRFA requires a multipronged approach, and as outlined in the paper, biotechnologies can provide powerful tools for the management of GRFA. These tools vary in complexity from those that are relatively simple to those that are more sophisticated. Further, advances in biotechnologies are occurring at a rapid pace and provide novel opportunities for more effective and efficient management of GRFA. Biotechnology applications must be integrated with ongoing conventional breeding and development programs in order to succeed. Additionally, the generation, adaptation, and adoption of biotechnologies require a consistent level of financial and human resources and appropriate policies need to be in place. These issues were also recognized by Member States at the FAO international technical conference on Agricultural Biotechnologies for Developing Countries (ABDC-10), which took place in March 2010 in Mexico. At the end of the conference, the Member States reached a number of key conclusions, agreeing, inter alia, that developing countries should significantly increase sustained investments in capacity building and the development and use of biotechnologies to maintain the natural resource base; that effective and enabling national biotechnology policies and science-based regulatory frameworks can

  17. Agricultural biotechnologies in developing countries and their possible contribution to food security.

    Science.gov (United States)

    Ruane, John; Sonnino, Andrea

    2011-12-20

    Latest FAO figures indicate that an estimated 925 million people are undernourished in 2010, representing almost 16% of the population in developing countries. Looking to the future, there are also major challenges ahead from the rapidly changing socio-economic environment (increasing world population and urbanisation, and dietary changes) and climate change. Promoting agriculture in developing countries is the key to achieving food security, and it is essential to act in four ways: to increase investment in agriculture, broaden access to food, improve governance of global trade, and increase productivity while conserving natural resources. To enable the fourth action, the suite of technological options for farmers should be as broad as possible, including agricultural biotechnologies. Agricultural biotechnologies represent a broad range of technologies used in food and agriculture for the genetic improvement of plant varieties and animal populations, characterisation and conservation of genetic resources, diagnosis of plant or animal diseases and other purposes. Discussions about agricultural biotechnology have been dominated by the continuing controversy surrounding genetic modification and its resulting products, genetically modified organisms (GMOs). The polarised debate has led to non-GMO biotechnologies being overshadowed, often hindering their development and application. Extensive documentation from the FAO international technical conference on Agricultural Biotechnologies in Developing Countries (ABDC-10), that took place in Guadalajara, Mexico, on 1-4 March 2010, gave a very good overview of the many ways that different agricultural biotechnologies are being used to increase productivity and conserve natural resources in the crop, livestock, fishery, forestry and agro-industry sectors in developing countries. The conference brought together about 300 policy-makers, scientists and representatives of intergovernmental and international non

  18. Biotechnology and the developing world. Finding ways to bridge the agricultural technology gap.

    Science.gov (United States)

    Platais, K W; Collinson, M P

    1992-03-01

    Biotechnology is a controversial subject that involves a range of scientific principles from basic tissue culture to genetic manipulation. Proponents include private sector capitalists, public sector researchers, and developing nation governments. Opponents include environmental organizations and social organizations involved in protecting the rights of developing nations. Biotechnology is being presented as the next step after the Green Revolution and the only way that the people of the developing world will be able to feed themselves in the next half century. Research by industrialized nations world wide total an estimated $11 billion with 66% being contributed by the private sector. Biotechnology represents somewhat of a dilemma. Since the majority of the work is being done by the private sector the interests of shareholders and profit are greater done by the private sector the interests of shareholders and profit are greater than that of public welfare or safety. The Consultative Group on International Agricultural Research (CGIAR) is one public sector group that is concerned about this problem. The countries of the developing world fall into 2 categories in relation to use of biotechnology: (1) those that have the potential to adapt imported biotechnologies to local conditions; (2) those that have little or no applied research capacity to effectively use biotechnologies. Currently only Brazil, China, India, and Thailand belong in the 1st category, all other developing countries fall into the 2nd. CGIAR believes it can help in 2 ways: (1) it can provide a bridge for needed information and germplasm between developed and developing countries; (2) it can help to ensure that the agricultural needs of developing countries are not lost. In 1990 CGIAR's plant and animal biotechnology research totaled $14.5 million which was less than 5% of the total CGIAR budget. Networking and institutions building are areas that CGIAR focuses on in an attempt to increase its affect

  19. Development and application of modern agricultural biotechnology in Botswana: the potentials, opportunities and challenges.

    Science.gov (United States)

    Batlang, Utlwang; Tsurupe, Gorata; Segwagwe, Amogelang; Obopile, Motshwari

    2014-07-03

    In Botswana, approximately 40% of the population live in rural areas and derive most of their livelihood from agriculture by keeping livestock and practising arable farming. Due to the nature of their farming practises livestock and crops are exposed to diseases and environmental stresses. These challenges offer opportunities for application of biotechnology to develop adaptable materials to the country's environment. On the other hand, the perceived risk of genetically modified organisms (GMOs) has dimmed the promise of the technology for its application in agriculture. This calls for a holistic approach to the application of biotechnology to address issues of biosafety of GMOs. We have therefore assessed the potentials, challenges and opportunities to apply biotechnology with specific emphasis on agriculture, taking cognisance of requirement for its research, development and application in research and teaching institutions. In order to achieve this, resource availability, infrastructure, human and laboratory requirements were analyzed. The analysis revealed that the country has the capacity to carry out research in biotechnology in the development and production of genetically modified crops for food and fodder crops. These will include gene discovery, genetic transformation and development of systems to comply with the world regulatory framework on biosafety. In view of the challenges facing the country in agriculture, first generation biotech crops could be released for production. Novel GM products for development may include disease diagnosis kits, animal disease vaccines, and nutrient use efficiency, drought, and pest and disease resistant food and fodder crops.

  20. Biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    The guidelines of the Biotechnology Program are research and development aiming to develop and manufacture products of pharmaceutical interest. This program has two main research areas, namely Pituitary Hormones and Biopharmaceuticals. The first one comprises a group with a long experience on Recombinant Human Pituitary Hormone synthesis, purification and characterization. The Biopharmaceutical area is dedicated to the research of isolation, structural analysis and biological activities in different biological system of macromolecules.

  1. Biotechnology 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-12-15

    This book deals with Bio-vision 2016 on the meaning and important contents Next, it reveals vision of biotechnology, current condition of biotechnology in the main countries such as the U.S, Japan, Eu and China, promoting nation biotechnology with promotion policy, support policy for biotechnology such as agriculture and forestry and information and communication, competitiveness of biotechnology, research development by fields and related industries and regulation and system on biotechnology.

  2. Biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The guidelines of the Biotechnology Program are research and development aiming to develop and manufacture products of pharmaceutical interest. This Program has two main research areas, namely Pituitary Hormones and Biopharmaceuticals. The first one comprises a group with a long experience on Recombinant Human Pituitary Hormone synthesis, purification and characterization. The Biopharmaceutical area is dedicated to the research of isolation, structural analysis and biological activities in different biological system of macromolecules. The Animal Laboratory Division of IPEN is responsible for the breeding and production of small laboratory animal.

  3. Biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-07-01

    The guidelines of the Biotechnology Program are research and development aiming at developing and manufacturing products of pharmaceutical interest. This Program has two main research areas, namely Pituitary Hormones and Biopharmaceuticals. The first one comprises a group with a long experience on Recombinant Human Pituitary Hormone synthesis, purification and characterization. Up to now they have worked mostly with human growth hormone (hGH), human prolactin (hPRL), human thyrotropin (hTSH), human follicle stimulating hormone (hFSH) and human luteotropin (hLH), with a particular emphasis on glycoprotein carbohydrate structures. An important research line is devoted to Growth Hormone Gene Therapy, working mostly on animal models: immunocompetent and immunodeficient-dwarf mice. For several years this development has been based on ex vivo grafting of transduced keratinocytes, while more recently very promising results have been obtained with the injections and electroporation of naked plasmid DNA. Besides research, they have also activities in the Biotechnological Production and Downstream Processing of the same recombinant hormones, which are produced in both E. coli and mammalian cells and in the development of joint-ventures with the National Industry. The biological effects of radiation on cells are also studied, specially concerning the administration of {sup 131}I together with thyroid-stimulating hormone in thyroid cancer. The Biopharmaceutical area is dedicated to the research of isolation, structural analysis and biological activities in different biological systems of macromolecules. These macromolecules are peptides or proteins, either native or recombinant with medical or pharmaceutical interest. During this period new proteins related to serine protease activity, breast cancer development and angiogenesis were described. The effects of ionizing radiation on macromolecules have also been investigated to detoxify animal venoms in order to improve antigens

  4. Biotechnologies

    Directory of Open Access Journals (Sweden)

    Rival Alain

    2001-07-01

    Full Text Available Today, a range of biotechnological approaches, from somatic embryogenesis to biomolecular research, play an increasingly important role in breeding strategies for oil palm (Elaeis guineensis Jacq.. Clonal micropropagation. Methods of cloning by in vitro culture led to the development of a micropropagation technique for oil palm based on somatic embryogenesis which was tested at the pilot stage on elite genotypes, thus enabling the production of high oil yielding clones. This phase allowed the identification of limiting factors associated with scaling-up, with respect in particular to the scale of mass production required to meet the needs of planters and to the problem of ensuring genetic fidelity in the regenerated plant material. These two concerns led researchers to look further into the underlying physiological and/or molecular mechanisms involved in somatic embryogenesis and the somaclonal variation events induced by the in vitro cloning procedure. Structural and functional genomics. Marker-assisted breeding in oil palm is a long-term multi-stage project including: molecular analysis of genetic diversity in both E. guineensis and E. oleifera germplasms; large scale development of PCR-based microsatellite markers; and parallel development of three genome mapping and QTL detection projects studying key agronomic characters. Post-genomics. In order to tackle the problem of the mantled flowering abnormality, which is induced during the micropropagation process, studies of gene expression have been carried out in tissue cultures as a means of establishing an early clonal conformity testing procedure. It is important to assess what kind of methodology is the most appropriate for clonal conformity testing by comparing RNA, protein and DNA (PCR based approaches. Parallel studies on genomic DNA methylation changes induced by tissue culture suggest that the latter may play an important role in the determination of the mantled abnormality.

  5. Development of agricultural biotechnology and biosafety regulations used to assess the safety of genetically modified crops in Iran.

    Science.gov (United States)

    Mousavi, Amir; Malboobi, Mohammad A; Esmailzadeh, Nasrin S

    2007-01-01

    Rapid progress in the application of biotechnological methodologies and development of genetically modified crops in Iran necessitated intensive efforts to establish proper organizations and prepare required rules and regulations at the national level to ensure safe application of biotechnology in all pertinent aspects. Practically, preparation of a national biotechnology strategic plan in the country coincided with development of a national biosafety framework that was the basis for the drafted biosafety law. Although biosafety measures were observed by researchers voluntarily, the establishment of national biosafety organizations since the year 2000 built a great capacity to deal with biosafety issues in the present and future time, particularly with respect to food and agricultural biotechnology.

  6. The Role of Biotechnology in Sustainable Agriculture: Views and Perceptions among Key Actors in the Swedish Food Supply Chain

    Directory of Open Access Journals (Sweden)

    Karin Edvardsson Björnberg

    2015-06-01

    Full Text Available Researchers have put forward agricultural biotechnology as one possible tool for increasing food production and making agriculture more sustainable. In this paper, it is investigated how key actors in the Swedish food supply chain perceive the concept of agricultural sustainability and the role of biotechnology in creating more sustainable agricultural production systems. Based on policy documents and semi-structured interviews with representatives of five organizations active in producing, processing and retailing food in Sweden, an attempt is made to answer the following three questions: How do key actors in the Swedish food supply chain define and operationalize the concept of agricultural sustainability? Who/what influences these organizations’ sustainability policies and their respective positions on agricultural biotechnology? What are the organizations’ views and perceptions of biotechnology and its possible role in creating agricultural sustainability? Based on collected data, it is concluded that, although there is a shared view of the core constituents of agricultural sustainability among the organizations, there is less explicit consensus on how the concept should be put into practice or what role biotechnology can play in furthering agricultural sustainability.

  7. Women in sustainable agriculture and food biotechnology key advances and perspectives on emerging topics

    CERN Document Server

    2017-01-01

    This volume describes the contributions made by women scientists to the field of agricultural biotechnology, the most quickly adopted agricultural practice ever adopted. It features the perspectives of women educators, researchers and key stakeholders towards the development, implementation and acceptance of this modern technology. It describes the multiplying contemporary challenges in the field, how women are overcoming technological barriers, and their thoughts on what the future may hold. As sustainable agricultural practices increasingly represent a key option in the drive towards building a greener global community, the scientific, technological and implementation issues covered in this book are vital information for anyone working in environmental engineering. Provides a broad analysis of the science of agriculture, focusing on the contributions of women to the field, from basic research to applied technology Offers insights into hot topics in the field across the life cycle, from genetic engineering t...

  8. RNAi technologies in agricultural biotechnology: The Toxicology Forum 40th Annual Summer Meeting.

    Science.gov (United States)

    Sherman, James H; Munyikwa, Tichafa; Chan, Stephen Y; Petrick, Jay S; Witwer, Kenneth W; Choudhuri, Supratim

    2015-11-01

    During the 40th Annual Meeting of The Toxicology Forum, the current and potential future science, regulations, and politics of agricultural biotechnology were presented and discussed. The meeting session described herein focused on the technology of RNA interference (RNAi) in agriculture. The general process by which RNAi works, currently registered RNAi-based plant traits, example RNAi-based traits in development, potential use of double stranded RNA (dsRNA) as topically applied pesticide active ingredients, research related to the safety of RNAi, biological barriers to ingested dsRNA, recent regulatory RNAi science reviews, and regulatory considerations related to the use of RNAi in agriculture were discussed. Participants generally agreed that the current regulatory framework is robust and appropriate for evaluating the safety of RNAi employed in agricultural biotechnology and were also supportive of the use of RNAi to develop improved crop traits. However, as with any emerging technology, the potential range of future products, potential future regulatory frameworks, and public acceptance of the technology will continue to evolve. As such, continuing dialogue was encouraged to promote education of consumers and science-based regulations.

  9. The Sociology of Agriculture in Transition: The Political Economy of Agriculture after Biotechnology

    OpenAIRE

    Gabriela Pechlaner

    2010-01-01

    In 2007, a global food crisis brought the topic of agriculture back into the public eye, and retriggered debates about the ability of agricultural industrialization to feed the world. As a nature-based process and an exception to capitalist industrialization, agriculture trends are difficult to assess. One of the more productive attempts to do so has developed conceptual tools that account for the distinction from typical capital accumulation patterns, notably Goodman,Sorj, and Wilkinson’s (1...

  10. Study on the Agricultural Biotechnology Innovation Based on the Product Differentiation

    Institute of Scientific and Technical Information of China (English)

    Gang; WU; Yong; DU

    2014-01-01

    Based on product differentiation,this paper researches the innovation of agricultural biotechnology. In the duopoly structure,the company’s investment in innovation is affected by the product differentiation,and the greater the difference,the greater the willingness to increase investment and improve quality; at the same time,low innovative cost companies will choose a higher level of investment in innovation and quality. If there is no difference between the products,the companies with high cost of innovation abandon quality competition,and the companies with low cost of innovation " monopolize" the market.

  11. Transgenic proteins in agricultural biotechnology: The toxicology forum 40th annual summer meeting.

    Science.gov (United States)

    Sherman, James H; Choudhuri, Supratim; Vicini, John L

    2015-12-01

    During the 40th Annual Meeting of The Toxicology Forum, the current and potential future science, regulations, and politics of agricultural biotechnology were presented and discussed. The range of current commercial crops and commercial crop traits related to transgenic proteins were reviewed and example crop traits discussed, including insecticidal resistance conferred by Bt proteins and the development of nutritionally enhanced food such as Golden Rice. The existing regulatory framework in the USA, with an emphasis on US FDA's role in evaluating the safety of genetically engineered crops under the regulatory umbrella of the FD&C Act was reviewed. Consideration was given to the polarized politics surrounding agricultural biotechnology, the rise of open access journals, and the influence of the internet and social media in shaping public opinion. Numerous questions related to misconceptions regarding current products and regulations were discussed, highlighting the need for more scientists to take an active role in public discourse to facilitate public acceptance and adoption of new technologies and to enable science-based regulations.

  12. Chinese public understanding of the use of agricultural biotechnology--a case study from Zhejiang Province of China.

    Science.gov (United States)

    Lü, Lan

    2006-04-01

    This study explores the Chinese public's perceptions of, and attitudes to, agriculture and food applications of biotechnology; and investigates the effect of socio-demographic factors on attitudes. A questionnaire survey and interviews were used in an attempt to combine quantitative analysis with qualitative review. The main finding of this study is that the Chinese population has a superficial, optimistic attitude to agricultural biotechnology; and that, in accordance with public attitudes, a cautious policy, with obligatory labelling, should be adopted. The study reveals that education is the factor among socio-demographic variables with the strongest impact on public attitudes. Higher education leads to a more positive evaluation of GM (genetically modified) foods and applications of biotechnology with respect to usefulness, moral acceptability, and suitability for encouragement. In addition, public attitudinal differences depend significantly on area of residence. Compared with their more urban compatriots, members of the public in less developed areas of China have more optimistic attitudes, perceive more benefits, and are more risk tolerant in relation to GM foods and agricultural biotechnology. Finally we obtained a very high rate of "don't know" answers to our survey questions. This suggests that many people do not have settled attitudes, and correspondingly, that the overall public attitude to agricultural biotechnology and GM foods in China is at present somewhat unstable.

  13. Chinese public understanding of the use of agricultural biotechnology--A case study from Zhejiang Province of China

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    This study explores the Chinese public's perceptions of, and attitudes to, agriculture and food applications of biotechnology; and investigates the effect of socio-demographic factors on attitudes. A questionnaire survey and interviews were used in an attempt to combine quantitative analysis with qualitative review. The main finding of this study is that the Chinese population has a superficial, optimistic attitude to agricultural biotechnology; and that, in accordance with public attitudes, a cautious policy,with obligatory labelling, should be adopted. The study reveals that education is the factor among socio-demographic variables with the strongest impact on public attitudes. Higher education leads to a more positive evaluation of GM (genetically modified)foods and applications of biotechnology with respect to usefulness, moral acceptability, and suitability for encouragement. In addition, public attitudinal differences depend significantly on area of residence. Compared with their more urban compatriots,members of the public in less developed areas of China have more optimistic attitudes, perceive more benefits, and are more risk tolerant in relation to GM foods and agricultural biotechnology. Finally we obtained a very high rate of"don't know" answers to our survey questions. This suggests that many people do not have settled attitudes, and correspondingly, that the overall public attitude to agricultural biotechnology and GM foods in China is at present somewhat unstable.

  14. Development of an agricultural biotechnology crop product: testing from discovery to commercialization.

    Science.gov (United States)

    Privalle, Laura S; Chen, Jingwen; Clapper, Gina; Hunst, Penny; Spiegelhalter, Frank; Zhong, Cathy X

    2012-10-17

    "Genetically modified" (GM) or "biotech" crops have been the most rapidly adopted agricultural technology in recent years. The development of a GM crop encompasses trait identification, gene isolation, plant cell transformation, plant regeneration, efficacy evaluation, commercial event identification, safety evaluation, and finally commercial authorization. This is a lengthy, complex, and resource-intensive process. Crops produced through biotechnology are the most highly studied food or food component consumed. Before commercialization, these products are shown to be as safe as conventional crops with respect to feed, food, and the environment. This paper describes this global process and the various analytical tests that must accompany the product during the course of development, throughout its market life, and beyond.

  15. Overcoming barriers to trust in agricultural biotechnology projects: a case study of Bt cowpea in Nigeria

    Directory of Open Access Journals (Sweden)

    Ezezika Obidimma C

    2012-11-01

    Full Text Available Abstract Background Nigeria, Africa’s most populous country, has been the world’s largest cowpea importer since 2004. The country is currently in the early phases of confined field trials for two genetically modified crops: Bacillus thuringiensis (Bt cowpea and nutritionally enhanced cassava (“BioCassava Plus”. Using the bio-safety guidelines process as a backdrop, we evaluate the role of trust in the operation of the Cowpea Productivity Improvement Project, which is an international agricultural biotechnology public-private partnership (PPP aimed at providing pest-resistant cowpea varieties to Nigerian farmers. Methods We reviewed the published literature and collected data through direct observations and semi-structured, face-to-face interviews. Data were analyzed based on emergent themes to create a comprehensive narrative on how trust is understood and built among the partners and with the community. Results Our findings highlight the importance of respecting mandates and eliminating conflicts of interest; holding community engagement initiatives early on; having on-going internal discussion and planning; and serving a locally-defined need. These four lessons could prove helpful to other agricultural biotechnology initiatives in which partners may face similar trust-related challenges. Conclusions Overcoming challenges to building trust requires concerted effort throughout all stages of project implementation. Currently, plans are being made to backcross the cowpea strain into a local variety in Nigeria. The development and adoption of the Bt cowpea seed hinges on the adoption of a National Biosafety Law in Nigeria. For countries that have decided to adopt biotech crops, the Nigerian cowpea experiment can be used as a model for other West African nations, and is actually applied as such in Ghana and Burkina Faso, interested in developing a Bt cowpea.

  16. Biotechnology 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-12-15

    This book first reveals prospect on biotechnology with low-carbon green growth Next, it consists of four chapters, which deal with vision of biotechnology, trend of biotechnology in main countries like the U.S, Eu, Japan and China, current condition for biotechnology with support and promoting policy such as health and medical treatment and maritime and fisheries, major product on investment, human power, paper and pattern, research development such as genomic, system biology, bio new medicine, agriculture, stock breeding and food, biological resources and legal system related biotechnology.

  17. Globalization, the rise of biotechnology and catching up in agricultural innovation: The case of Bt technology in India

    OpenAIRE

    Iizuka, M.; Thutupalli, A.

    2014-01-01

    The agricultural sector has played an important role in the provision of food, foreign exchange and sustainable energy to many developing countries. This sector, however, has not been considered as a driving force of innovation as compared to other productive sectors. However, recent economics and international business literature suggests that the agricultural sector (1) has become knowledge intensive with the rise of biotechnology (Bt); and (2) is a sector where firms in developing countrie...

  18. Towards personalized agriculture: What chemical genomics can bring to plant biotechnology

    Directory of Open Access Journals (Sweden)

    Michael E Stokes

    2014-07-01

    Full Text Available In contrast to the dominant drug paradigm in which compounds were developed to fit all, new models focused around personalized medicine are appearing where treatments are customized for individual patients. The agricultural biotechnology industry should also think about these new personalized models. For example, most common herbicides are generic in action, which led to the development of genetically modified crops to add specificity. The ease and accessibility of modern genomic analysis should facilitate the discovery of chemicals that are more selective in their utility. Is it possible to develop species-selective herbicides and growth regulators? More generally put, is plant research at a stage where chemicals can be developed that streamline plant development and growth to various environments? We believe the advent of chemical genomics now opens up these and other opportunities to personalize agriculture. Furthermore, chemical genomics does not necessarily require genetically tractable plant models, which in principle should allow quick translation to practical applications. For this to happen, however, will require collaboration between the Ag-biotech industry and academic labs for early-stage research and development.

  19. An intellectual property sharing initiative in agricultural biotechnology: development of broadly accessible technologies for plant transformation.

    Science.gov (United States)

    Chi-Ham, Cecilia L; Boettiger, Sara; Figueroa-Balderas, Rosa; Bird, Sara; Geoola, Josef N; Zamora, Pablo; Alandete-Saez, Monica; Bennett, Alan B

    2012-06-01

    The Public Intellectual Property Resource for Agriculture (PIPRA) was founded in 2004 by the Rockefeller Foundation in response to concerns that public investments in agricultural biotechnology benefiting developing countries were facing delays, high transaction costs and lack of access to important technologies due to intellectual property right (IPR) issues. From its inception, PIPRA has worked broadly to support a wide range of research in the public sector, in specialty and minor acreage crops as well as crops important to food security in developing countries. In this paper, we review PIPRA's work, discussing the failures, successes, and lessons learned during its years of operation. To address public sector's limited freedom-to-operate, or legal access to third-party rights, in the area of plant transformation, we describe PIPRA's patent 'pool' approach to develop open-access technologies for plant transformation which consolidate patent and tangible property rights in marker-free vector systems. The plant transformation system has been licensed and deployed for both commercial and humanitarian applications in the United States (US) and Africa, respectively.

  20. Biotechnology opportunities in agriculture. June 1980-November 1989 (A Bibliography from the Management Contents data base). Report for June 1980-November 1989

    Energy Technology Data Exchange (ETDEWEB)

    1990-04-01

    This bibliography contains citations concerning advances in biotechnology and their impact on agricultural and food production markets. Crop growth stimulators, pharmaceutical products developed using biotechnology, poultry vaccines, salt tolerant plants, genetically engineered immune properties in plants and animals, and food crops of uniform size with improved flavor are among the products discussed. Specific company investments and activities in the biotechnology field are included. (This updated bibliography contains 155 citations, 19 of which are new entries to the previous edition.)

  1. Novel Techniques and Their Wide Applications to Health Foods, Medical and Agricultural Biotechnology in Relation to Policy Making on Genetically Modified Crops and Foods

    CERN Document Server

    Baianu, I C; Lozano, P; Lin, H C

    2004-01-01

    Selected applications of novel techniques in Agricultural Biotechnology, Health Food formulations and Medical Biotechnology are being reviewed with the aim of unraveling future developments and policy changes that are likely to open new markets for Biotechnology and prevent the shrinking or closing of existing ones. Amongst the selected novel techniques with applications in both Agricultural and Medical Biotechnology are: immobilized bacterial cells and enzymes, microencapsulation and liposome production, genetic manipulation of microorganisms, development of novel vaccines from plants, epigenomics of mammalian cells and organisms, and biocomputational tools for molecular modeling related to disease and Bioinformatics. Both fundamental and applied aspects of the emerging new techniques are being discussed in relation to their anticipated, marked impact on future markets and present policy changes that are needed for success in either Agricultural or Medical Biotechnology. The novel techniques are illustrated ...

  2. Beyond knowledge transfer: The social construction of autonomous academic science in university-industry agricultural biotechnology research collaborations

    Science.gov (United States)

    Biscotti, Dina Louise

    Autonomy is a social product. Although some might view autonomy as the absence of social interference in individual action, it is in fact produced through social institutions. It enables social actors to act; it is the justification for the allocation of enormous public resources into institutions classified as "public" or "nonprofit;" it can lead to innovation; and, significantly, it is key to the public acceptance of new technologies. In this dissertation, I analyze the social construction of autonomy for academic science in U.S. university-industry agricultural biotechnology research collaborations. University-industry relationships (UIRs) are a site of concern about the influence of commercial interests on academic science. Agricultural biotechnology is a contentious technology that has prompted questions about the ecological and public health implications of genetically-modified plants and animals. It has also spurred awareness of the industrialization of agriculture and accelerating corporate control of the global food system. Through analysis of in-depth interviews with over 200 scientists and administrators from nine U.S. research universities and thirty agricultural biotechnology companies, I find that both the academy and industry have a vested interest in the social construction of the academy as an autonomous space from which claims to objective, disinterested scientific knowledge can be made. These claims influence government regulation, as well as grower and public acceptance of agricultural biotechnology products. I argue that the social production of autonomy for academic science can be observed in narratives and practices related to: (1) the framing of when, how and why academic scientists collaborate with industry, (2) the meanings ascribed to and the uses deemed appropriate for industry monies in academic research, and (3) the dissemination of research results into the public domain through publications and patents. These narratives and practices

  3. Bioenergy and the potential contribution of agricultural biotechnologies in developing countries

    Energy Technology Data Exchange (ETDEWEB)

    Ruane, John [FAO Working Group on Biotechnology, UN Food and Agriculture Organization (FAO), Viale delle Terme di Caracalla, 00153 Rome (Italy); Sonnino, Andrea [FAO Office of Knowledge Exchange, Research and Extension, UN Food and Agriculture Organization (FAO), Viale delle Terme di Caracalla, 00153 Rome (Italy); Agostini, Astrid [FAO Investment Centre, UN Food and Agriculture Organization (FAO), Viale delle Terme di Caracalla, 00153 Rome (Italy)

    2010-10-15

    We provide an overview of the current status of bioenergy development, focusing on first- and second-generation liquid biofuels, considering drivers of growth and risks that have raised concerns over recent years. We also describe the main areas where biotechnologies are being, or can be, applied for production of first- and second-generation biofuels as well as microalgal biodiesel and biogas. Greatest attention is paid to second-generation biofuels in the review because of the large expectations they have created and because of the significant role that biotechnology applications are likely to play in their development. We close with some specific considerations regarding applying biotechnologies for bioenergy development in developing countries. (author)

  4. Future Public Policy and Ethical Issues Facing the Agricultural and Microbial Genomics Sectors of the Biotechnology Industry: A Roundtable Discussion

    Energy Technology Data Exchange (ETDEWEB)

    Diane E. Hoffmann

    2003-09-12

    On September 12, 2003, the University of Maryland School of Law's Intellectual Property and Law & Health Care Programs jointly sponsored and convened a roundtable discussion on the future public policy and ethical issues that will likely face the agricultural and microbial genomics sectors of the biotechnology industry. As this industry has developed over the last two decades, societal concerns have moved from what were often local issues, e.g., the safety of laboratories where scientists conducted recombinant DNA research on transgenic microbes, animals and crops, to more global issues. These newer issues include intellectual property, international trade, risks of genetically engineered foods and microbes, bioterrorism, and marketing and labeling of new products sold worldwide. The fast paced nature of the biotechnology industry and its new developments often mean that legislators, regulators and society, in general, must play ''catch up'' in their efforts to understand the issues, the risks, and even the benefits, that may result from the industry's new ways of conducting research, new products, and novel methods of product marketing and distribution. The goal of the roundtable was to develop a short list of the most significant public policy and ethical issues that will emerge as a result of advances in these sectors of the biotechnology industry over the next five to six years. More concretely, by ''most significant'' the conveners meant the types of issues that would come to the attention of members of Congress or state legislators during this time frame and for which they would be better prepared if they had well researched and timely background information. A concomitant goal was to provide a set of focused issues for academic debate and scholarship so that policy makers, industry leaders and regulators would have the intellectual resources they need to better understand the issues and concerns at stake. The

  5. The Two Cultures of Science:Implications for University-Industry Relationships in the U.S. Agriculture Biotechnology

    Institute of Scientific and Technical Information of China (English)

    William B. Lacy; Leland L. Glenna; Dina Biscotti; Rick Welsh; Kate Clancy

    2014-01-01

    Partnerships between U.S. universities and industries have existed for several decades and in recent years have become generally more varied, wider in scope, more aggressive and experimental and higher in public visibility. In addition, in the last few decades, public and private interests have advocated for government policies and laws to globally promote the commercialization of university science. This paper examines the persistence or convergence of the two cultures of science and the implications of this commercialization for university-industry relationships in agriculture biotechnology. The perceptions and values of over 200 U.S. university and industry scientists, managers and administrators who participate in or oversee research collaborations in agricultural biotechnology were analyzed. The ifndings revealed that the participants in these research relationships continue to perceive very distinct cultures of science and identify a wide range of concerns and disadvantages of these partnerships. Several actions were discussed to ensure that the two cultures serve complementary roles and that they maximize the public beneifts from these increasing collaborations.

  6. Agricultural biology in the 3rd millennium: nutritional food security & specialty crops through sustainable agriculture and biotechnology

    Science.gov (United States)

    Food security and agricultural sustainability are of prime concern in the world today in light of the increasing trends in population growth in most parts of the globe excepting Europe. The need to develop capacity to produce more to feed more people is complicated since the arable land is decreasin...

  7. Ascendancy of agricultural biotechnology in the Australian political mainstream coexists with technology criticism by a vocal-minority.

    Science.gov (United States)

    Tribe, David

    2014-07-01

    Australia is a federation of States. This political structure necessitates collaborative arrangements between Australian governments to harmonize national regulation of gene technology and food standards. Extensive political negotiation among institutions of federal government has managed regulation of GM crops and food. Well-developed human resources in Australian government provided numerous policy documents facilitating a transparent political process. Workable legislation has been devised in the face of criticisms of gene technology though the political process. Conflicts between potential disruptions to food commodity trade by precautionary proposals for environmental protection were one cause of political tensions, and differences in policy priorities at regional political levels versus national and international forums for negotiation were another. Australian policy outcomes on GM crops reflect (a) strong economic self-interest in innovative and productive farming, (b) reliance on global agricultural market reforms through the Cairns trade group and the WTO, and (c) the importance of Codex Alimentarius and WTO instruments SPS and TBT. Precautionary frameworks for GM food safety assurance that are inconsistent with WTO obligations were avoided in legislation. Since 2008 the 2 major parties, Australian Labor Party (ALP) and the Liberals appear to have reached a workable consensus at the Federal policy level about an important role for agricultural biotechnology in Australia's economic future.

  8. Antimicrobial peptide production and plant-based expression systems for medical and agricultural biotechnology.

    Science.gov (United States)

    Holaskova, Edita; Galuszka, Petr; Frebort, Ivo; Oz, M Tufan

    2015-11-01

    Antimicrobial peptides (AMPs) are vital components of the innate immune system of nearly all living organisms. They generally act in the first line of defense against various pathogenic bacteria, parasites, enveloped viruses and fungi. These low molecular mass peptides are considered prospective therapeutic agents due to their broad-spectrum rapid activity, low cytotoxicity to mammalian cells and unique mode of action which hinders emergence of pathogen resistance. In addition to medical use, AMPs can also be employed for development of innovative approaches for plant protection in agriculture. Conferred disease resistance by AMPs might help us surmount losses in yield, quality and safety of agricultural products due to plant pathogens. Heterologous expression in plant-based systems, also called plant molecular farming, offers cost-effective large-scale production which is regarded as one of the most important factors for clinical or agricultural use of AMPs. This review presents various types of AMPs as well as plant-based platforms ranging from cell suspensions to whole plants employed for peptide production. Although AMP production in plants holds great promises for medicine and agriculture, specific technical limitations regarding product yield, function and stability still remain. Additionally, establishment of particular stable expression systems employing plants or plant tissues generally requires extended time scale for platform development compared to certain other heterologous systems. Therefore, fast and promising tools for evaluation of plant-based expression strategies and assessment of function and stability of the heterologously produced AMPs are critical for molecular farming and plant protection.

  9. VARIETY DEMAND IN AN INTEGRATED AGRICULTURAL HOUSEHOLD MODEL WITH ATTRIBUTES: IMPLICATIONS FOR EMERGING CROP BIOTECHNOLOGIES

    OpenAIRE

    Edmeades, Svetlana; Phaneuf, Daniel J.; Smale, Melinda; Renkow, Mitch

    2004-01-01

    In this paper we consider the role of variety attributes in an agricultural household model of variety planting decisions. In an application to banana production in Uganda we derive a system of derived demands for a set of available banana varieties. Our empirical model uses a hudle/count data framework to examine simaltaneously the likelihood a household has experience with a given variety, and the amount of the variety that is planted. We find that production, consumption, and pest resistan...

  10. ENVIRONMENTAL RISK MANAGEMENT OF BIOTECHNOLOGY

    Science.gov (United States)

    The last two decades have shown remarkable advances in the field of biotechnology. We have processes using biotechnology to produce materials from commodity chemicals to pharmaceuticals. The application to agriculture has shown the introduction of transgenic crops with pesticidal...

  11. Citation Analysis of Dissertations in Molecular Biology and Biotechnology: A Case Study of G. B. Pant University of Agriculture and Technology, India

    Directory of Open Access Journals (Sweden)

    Hema Haldua

    2012-06-01

    Full Text Available Citation analysis and ranking of journals are key aspects of knowledge management and collection development in academic and research libraries. This paper aims to assist the library collection development in order to fulfill the needs of scientists and research scholars. The study covered the period 1998–2010 and used the reference lists of dissertations submitted by the doctoral students of the molecular biology and biotechnology sciences at the G. B. Pant University of Agriculture and Technology, Pantnagar, India. The findings of the study showed that citation analysis is a valid, reliable and practical method to provide reasonably accurate information on the use of molecular biology and biotechnology literature by doctoral students. Publishing research in high-quality journals is an integral part of academic life. Therefore, researchers often refer to journal rankings when making decisions to submit and publish their research findings.

  12. [Agricultural biotechnology safety assessment].

    Science.gov (United States)

    McClain, Scott; Jones, Wendelyn; He, Xiaoyun; Ladics, Gregory; Bartholomaeus, Andrew; Raybould, Alan; Lutter, Petra; Xu, Haibin; Wang, Xue

    2015-01-01

    Genetically modified (GM) crops were first introduced to farmers in 1995 with the intent to provide better crop yield and meet the increasing demand for food and feed. GM crops have evolved to include a thorough safety evaluation for their use in human food and animal feed. Safety considerations begin at the level of DNA whereby the inserted GM DNA is evaluated for its content, position and stability once placed into the crop genome. The safety of the proteins coded by the inserted DNA and potential effects on the crop are considered, and the purpose is to ensure that the transgenic novel proteins are safe from a toxicity, allergy, and environmental perspective. In addition, the grain that provides the processed food or animal feed is also tested to evaluate its nutritional content and identify unintended effects to the plant composition when warranted. To provide a platform for the safety assessment, the GM crop is compared to non-GM comparators in what is typically referred to as composition equivalence testing. New technologies, such as mass spectrometry and well-designed antibody-based methods, allow better analytical measurements of crop composition, including endogenous allergens. Many of the analytical methods and their intended uses are based on regulatory guidance documents, some of which are outlined in globally recognized documents such as Codex Alimentarius. In certain cases, animal models are recommended by some regulatory agencies in specific countries, but there is typically no hypothesis or justification of their use in testing the safety of GM crops. The quality and standardization of testing methods can be supported, in some cases, by employing good laboratory practices (GLP) and is recognized in China as important to ensure quality data. Although the number of recommended, in some cases, required methods for safety testing are increasing in some regulatory agencies, it should be noted that GM crops registered to date have been shown to be comparable to their nontransgenic counterparts and safe . The crops upon which GM development are based are generally considered safe.

  13. The 5th World Congress of chemical engineering: Technologies critical to a changing World. Volume II: Agriculture, food biotechnology biomedical electric power process safety

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    Volume 2 of the proceedings from the 5th World Congress of Chemical Engineering covers four major topic areas from which papers were selected for the database: Agriculture, Food; Biotechnology; Electric Power, and Process Safety. Pertinent subtopics include: Renewable Resource Engineering; Special Processes in the Food Industry; Advances in Metabolite Production; Advances in Fermentation and Cell Culture Engineering; Coal and Nuclear Central Station Power Plants; Large Natural Gas Fired Power Stations; Distributed Generation; Potential Impact of Biomass Energy; and Chemical Hazards in Plant Design. 29 papers were selected from Volume 1 for the database.

  14. Globalization, the rise of biotechnology and catching up in agricultural innovation: The case of Bt technology in India

    NARCIS (Netherlands)

    Iizuka, M.; Thutupalli, A.

    2014-01-01

    The agricultural sector has played an important role in the provision of food, foreign exchange and sustainable energy to many developing countries. This sector, however, has not been considered as a driving force of innovation as compared to other productive sectors. However, recent economics and i

  15. Industrial biotechnology: tools and applications.

    Science.gov (United States)

    Tang, Weng Lin; Zhao, Huimin

    2009-12-01

    Industrial biotechnology involves the use of enzymes and microorganisms to produce value-added chemicals from renewable sources. Because of its association with reduced energy consumption, greenhouse gas emissions, and waste generation, industrial biotechnology is a rapidly growing field. Here we highlight a variety of important tools for industrial biotechnology, including protein engineering, metabolic engineering, synthetic biology, systems biology, and downstream processing. In addition, we show how these tools have been successfully applied in several case studies, including the production of 1, 3-propanediol, lactic acid, and biofuels. It is expected that industrial biotechnology will be increasingly adopted by chemical, pharmaceutical, food, and agricultural industries.

  16. Challenges of climate change: omics-based biology of saffron plants and organic agricultural biotechnology for sustainable saffron production.

    Science.gov (United States)

    Husaini, Amjad M

    2014-01-01

    Kashmir Valley is a major saffron (Crocus sativus Kashmirianus) growing area of the world, second only to Iran in terms of production. In Kashmir, saffron is grown on uplands (termed in the local language as "Karewas"), which are lacustrine deposits located at an altitude of 1585 to 1677 m above mean sea level (amsl), under temperate climatic conditions. Kashmir, despite being one of the oldest historical saffron-producing areas, faces a rapid decline of saffron industry. Among many other factors responsible for decline of saffron industry the preponderance of erratic rainfalls and drought-like situation have become major challenges imposed by climate change. Saffron has a limited coverage area as it is grown as a 'niche crop' and is a recognized "geographical indication," growing under a narrow microclimatic condition. As such it has become a victim of climate change effects, which has the potential of jeopardizing the livelihood of thousands of farmers and traders associated with it. The paper discusses the potential and actual impact of climate change process on saffron cultivation in Kashmir; and the biotechnological measures to address these issues.

  17. 转基因农业生物技术安全隐忧及其监管研究%Studies on Supervision of the Underlying Worry in Security of Transgenic Agricultural Biotechnology

    Institute of Scientific and Technical Information of China (English)

    柏振忠; 王红玲

    2011-01-01

    随着转基因农业生物技术的迅猛发展,由其带来的潜在风险也日益被世人所关注。文章指出转基因农业生物技术在转基因农产品的食用安全性、转基因农作物的环境安全性、目的基因的遗传与表达稳定性等方面存在潜在风险,并在总结转基因农业生物技术安全监管的国际经验的基础上,提出我国应在防止不同农作物之间的基因漂移、完善转基因农产品的标识制度、加大转基因技术的研究力度等方面加强转基因农业生物技术的安全监管。%Development of transgenic agricultural biotechnology has made huge progress.However,the potential risks from it had been paid attention to by many people.It was pointed out in the paper that transgenic agricultural biotechnology may lead to some risks,such as the security in food for transgenic agricultural products,the security in circumstance for transgenic crops,and the stability in inheritance and expression for the target gene.Based on summing up international experiences on how to supervise the security of transgenic agricultural biotechnology,several advices for China were given,including preventing gene flow between different crops,perfecting labeling system of transgenic agricultural products,strengthening studies in transgenic agricultural biotechnology.

  18. Current state of biotechnology in Turkey.

    Science.gov (United States)

    Dundar, Munis; Akbarova, Yagut

    2011-09-01

    Biotechnology is an interdisciplinary branch of science that encompasses a wide range of subjects like genetics, virology, microbiology, immunology, engineering to develop vaccines, and so on and plays a vital role in health systems, crop and seed management, yield improvement, agriculture, soil management, ecology, animal farming, cellular process, bio statistics, and so on. This article is about activities in medical and pharmaceutical biotechnology, environmental biotechnology, agricultural biotechnology and nanobiotechnology carried out in Turkey. Turkey has made some progress in biotechnology projects for research and development.

  19. Fungal biodiversity to biotechnology.

    Science.gov (United States)

    Chambergo, Felipe S; Valencia, Estela Y

    2016-03-01

    Fungal habitats include soil, water, and extreme environments. With around 100,000 fungus species already described, it is estimated that 5.1 million fungus species exist on our planet, making fungi one of the largest and most diverse kingdoms of eukaryotes. Fungi show remarkable metabolic features due to a sophisticated genomic network and are important for the production of biotechnological compounds that greatly impact our society in many ways. In this review, we present the current state of knowledge on fungal biodiversity, with special emphasis on filamentous fungi and the most recent discoveries in the field of identification and production of biotechnological compounds. More than 250 fungus species have been studied to produce these biotechnological compounds. This review focuses on three of the branches generally accepted in biotechnological applications, which have been identified by a color code: red, green, and white for pharmaceutical, agricultural, and industrial biotechnology, respectively. We also discuss future prospects for the use of filamentous fungi in biotechnology application.

  20. Natural transformation in plant breeding - a biotechnological platform for quality improvement of ornamental, agricultural and medicinal plants

    DEFF Research Database (Denmark)

    Lütken, Henrik Vlk; Hegelund, Josefine Nymark; Himmelboe, Martin;

    2015-01-01

    Compactness is a desirable trait in ornamental plant breeding because it is preferred by producers, distributors and consumers. Presently, in ornamental plant production growth of many potted plants is regulated by application of chemical growth retardants, several of which are harmful to both......, decreased plant height, short internodes, reduced apical dominance and changes in flower characteristics. Several of these traits improve ornamental plant quality and may also benefit characteristics useful in agricultural field crops. In addition, a number of regenerated plants derived from hairy roots...

  1. Genetic manipulation in biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Sherwood, R.; Atkinson, T.

    1981-04-04

    The role of genetic manipulation in opening up new possibilities in biotechnology is discussed and the basic steps in a recombinant DNA experiment are summarized. Some current and future applications of this technology in the fields of medicine, industry and agriculture are presented, including, conversion of wastes to SCP, chemicals and alcohols, plant improvement and the introduction of nitrogen fixation genes into plants as an alternative to the use of nitrogen fertilizers.

  2. Editorial: Biotechnology Journal's diverse coverage of biotechnology.

    Science.gov (United States)

    Wink, Michael

    2014-03-01

    This issue of Biotechnology Journal is a regular issue edited by Prof. Michael Wink. The issue covers all the major focus areas of the journal, including medical biotechnology, synthetic biology, and novel biotechnological methods.

  3. Biotechnology: Challenge for the food industry

    Directory of Open Access Journals (Sweden)

    Popov Stevan

    2007-01-01

    Full Text Available According to the broadest definition, biotechnology is the use of living matter (plants, animals and microorganisms in industry, environment protection, medicine and agriculture. Biotechnology takes a key position in the field of food processing during thousands of years. Last about fifty years brought dynamical development of knowledges in the natural sciences especially in domain of genetics and manipulation of genes. Biotechnology for which active role in the on-coming times could be foreseen, not only with respect of R&D, but also in general technological development represents scope of priority in the USA and in European Union (EU as well. It is accepted that the results achieved in biotechnology oversize scientific domain and find their entrance into economics, legislation, quality of life and even of politics. Corresponding with the definition of biotechnology as "the integration of natural sciences and engineering in the application of microorganisms, cells, their components and molecular analogues in production (General assembly of the European federation for Biotechnology, 1989 European Commission (1999 adopted the biotechnological taxonomy, i.e. fields and sub-fields of biotechnology. R&D activities in this domain are oriented to eight fields and branched through them. Fields of biotechnology (EC, 1999 are: 1 Plant biotechnology (agricultural cultivars, trees, bushes etc; 2 Animal biotechnology; 3 Biotechnology in environment protection; 4 Industrial biotechnology (food, feed, paper, textile, pharmaceutical and chemical productions; 5 Industrial biotechnology (production of cells and research of cells - producers of food and of other commodities; 6 Development of humane and veterinarian diagnostics (therapeutical systems 7 Development of the basic biotechnology, and 8 Nontechnical domains of biotechnology. In concordance with some judgments, in the World exist about 4000 biotechnological companies. World market of biotechnological

  4. Relevance of chemistry to white biotechnology

    OpenAIRE

    Raghava Smita; Gupta Munishwar N

    2007-01-01

    Abstract White biotechnology is a fast emerging area that concerns itself with the use of biotechnological approaches in the production of bulk and fine chemicals, biofuels, and agricultural products. It is a truly multidisciplinary area and further progress depends critically on the role of chemists. This article outlines the emerging contours of white biotechnology and encourages chemists to take up some of the challenges that this area has thrown up.

  5. Relevance of chemistry to white biotechnology

    Directory of Open Access Journals (Sweden)

    Raghava Smita

    2007-06-01

    Full Text Available Abstract White biotechnology is a fast emerging area that concerns itself with the use of biotechnological approaches in the production of bulk and fine chemicals, biofuels, and agricultural products. It is a truly multidisciplinary area and further progress depends critically on the role of chemists. This article outlines the emerging contours of white biotechnology and encourages chemists to take up some of the challenges that this area has thrown up.

  6. Relevance of chemistry to white biotechnology.

    Science.gov (United States)

    Gupta, Munishwar N; Raghava, Smita

    2007-06-20

    White biotechnology is a fast emerging area that concerns itself with the use of biotechnological approaches in the production of bulk and fine chemicals, biofuels, and agricultural products. It is a truly multidisciplinary area and further progress depends critically on the role of chemists. This article outlines the emerging contours of white biotechnology and encourages chemists to take up some of the challenges that this area has thrown up.

  7. The R & D Market Structure of Agricultural Biotechnology Firm in Taiwan%台湾农业生物技术厂商研发市场结构分析

    Institute of Scientific and Technical Information of China (English)

    池敏青; 王海平; 周琼

    2013-01-01

    农业生技产业的长期发展很大程度上取决于相关厂商的实际技术和产品开发效率,与厂商研发创新能力密切相关。该文从研发经费投入、研发经费支出、研发主要成效、研发面临的主要问题,以及厂商研发受政府辅助影响5个方面对台湾当前农业生技厂商研发市场结构进行分析总结,并从企业战略合作、资金募集渠道、研发基础设施、研发人才队伍等方面提出了进一步提高台湾农业生技厂商研发效率的对策建议。%The long-term development of agricultural biotechnology industry depends largely on the relevant manufacturers of the actual technology and product development efficiency, and is closely related to R&D innovation ability. This article from the R&D, R&D expenditures, R&D major achievements, development problems, and R&D firms under government aided effect 5 aspects to the Taiwan Agricultural Biotechnology R&D market structure analysis. And cooperation, from the enterprise strategy, fund raising channels, R&D infrastructure, R&D personnel etc. to put forward a proposal to improve the Taiwan agricultural biotechnology industry development.

  8. STRENGTHENING BIOTECHNOLOGY RESEARCH IN INDONESIA

    Directory of Open Access Journals (Sweden)

    S. Sastrapradja

    2012-09-01

    Full Text Available The wave of biotechnology promises has struck not only the developed countries but the developing countries as well. The scientific community in Indonesia is aware of the opportunities and is eager to take an active part in this particular endeavour. Meanwhile resources are required to welcoming the biotech­nology era. The need of trained manpower, appropriate infrastructure and equipment, operational and maintenance costs requires serious consideration if a unit or a laboratory is expected to be functional in biotechnology. There is a good opportunity of applying biotechnology in the field of agriculture and industry considering the availability of biological resources in Indonesia. This paper outlines what have been done so far, the difficulties encountered and the efforts made to strengthening biotechnology research in Indonesia.

  9. Analysis on the Development Status of Transgenic Biotechnology in Agricultural Field%转基因生物技术在农业领域的发展现状分析

    Institute of Scientific and Technical Information of China (English)

    何礼健; 周玉婷; 左停

    2011-01-01

    The development status, superiorities and potential risks of transgenic biotechnology in agricultural field were summarized, based on which the development prospect and trend of GM crop were briefly analyzed.%概述了转基因生物技术在农业领域的发展现状,拥有的发展优势及其可能带来的风险,在此基础上简要分析了转基因农作物的发展前景和趋势.

  10. Cotton, biotechnology, and economic development

    OpenAIRE

    Baffes, John

    2011-01-01

    During the past decade, cotton prices remained considerably below other agricultural prices (although they recovered toward the end of 2010). Yet, between 2000-04 and 2005-09 world cotton production increased 13 percent. This paper conjectures that biotechnology-induced productivity improvements increased supplies by China and India, which, in addition to keeping cotton prices low, aided t...

  11. Biotechnology's foreign policy.

    Science.gov (United States)

    Feldbaum, Carl

    2002-01-01

    From its inception, biotechnology has been a uniquely international enterprise. An American and an Englishman working together elucidated the structure of DNA almost 50 years ago; more recently, the Human Genome Project linked researchers around the world, from the Baylor College of Medicine in Houston to the Beijing Human Genome Center. Today our industry's researchers hail from African villages and Manhattan high rises; from Munich and Melbourne; from London, Ontario, and London, England; from Scotland and Nova Scotia--New Scotland; from Calcutta and Calgary. But in the beginning, the infrastructure that supported these efforts--intellectual property, venture capital, streamlined technology transfer--was less widely dispersed and the world's brightest biotech researchers clustered in only half a dozen scientific Meccas. Previous technological revolutions have spread around the world. Following in their footsteps, biotechnology's global diaspora seems inevitable, especially since governments are promoting it. But as our science and business emigrate from early strongholds in the United States, Canada and Europe across oceans and borders and into new cultures, international tensions over biotechnology continue to grow. In just the last few years, controversies have rolled over R&D spending priorities, genetic patents, bioprospecting, transgenic agriculture and drug pricing. My premise today is that our industry needs to formulate its first foreign policy, one which is cognizant of the miserable judgments and mistakes of other industries--and avoids them.

  12. Theme: The Role of Science in the Agricultural Education Curriculum.

    Science.gov (United States)

    Agricultural Education Magazine, 2002

    2002-01-01

    Thirteen theme articles discuss integration of science and agriculture, the role of science in agricultural education, biotechnology, agriscience in Tennessee and West Virginia, agriscience and program survival, modernization of agricultural education curriculum, agriscience and service learning, and biotechnology websites. (SK)

  13. Biotechnology in maize breeding

    Directory of Open Access Journals (Sweden)

    Mladenović-Drinić Snežana

    2004-01-01

    Full Text Available Maize is one of the most important economic crops and the best studied and most tractable genetic system among monocots. The development of biotechnology has led to a great increase in our knowledge of maize genetics and understanding of the structure and behaviour of maize genomes. Conventional breeding practices can now be complemented by a number of new and powerful techniques. Some of these often referred to as molecular methods, enable scientists to see the layout of the entire genome of any organism and to select plants with preferred characteristics by "reading" at the molecular level, saving precious time and resources. DNA markers have provided valuable tools in various analyses ranging from phylogenetic analysis to the positional cloning of genes. Application of molecular markers for genetic studies of maize include: assessment of genetic variability and characterization of germ plasm, identification and fingerprinting of genotypes, estimation of genetic distance, detection of monogamic and quantitative trait loci, marker assisted selection, identification of sequence of useful candidate genes, etc. The development of high-density molecular maps which has been facilitated by PCR-based markers, have made the mapping and tagging of almost any trait possible and serve as bases for marker assisted selection. Sequencing of maize genomes would help to elucidate gene function, gene regulation and their expression. Modern biotechnology also includes an array of tools for introducing or deieting a particular gene or genes to produce plants with novel traits. Development of informatics and biotechnology are resulted in bioinformatic as well as in expansion of microarrey technique. Modern biotechnologies could complement and improve the efficiency of traditional selection and breeding techniques to enhance agricultural productivity.

  14. Biotechnology opportunities on Space Station

    Science.gov (United States)

    Deming, Jess; Henderson, Keith; Phillips, Robert W.; Dickey, Bernistine; Grounds, Phyllis

    1987-01-01

    Biotechnology applications which could be implemented on the Space Station are examined. The advances possible in biotechnology due to the favorable microgravity environment are discussed. The objectives of the Space Station Life Sciences Program are: (1) the study of human diseases, (2) biopolymer processing, and (3) the development of cryoprocessing and cryopreservation methods. The use of the microgravity environment for crystal growth, cell culturing, and the separation of biological materials is considered. The proposed Space Station research could provide benefits to the fields of medicine, pharmaceuticals, genetics, agriculture, and industrial waste management.

  15. Editorial: Biotechnology Journal brings more than biotechnology.

    Science.gov (United States)

    Jungbauer, Alois; Lee, Sang Yup

    2015-09-01

    Biotechnology Journal always brings the state-of-the-art biotechnologies to our readers. Different from other topical issues, this issue of Biotechnology Journal is complied with a series of exiting reviews and research articles from spontaneous submissions, again, addressing society's actual problems and needs. The progress is a real testimony how biotechnology contributes to achievements in healthcare, better utilization of resources, and a bio-based economy.

  16. BIOTECHNOLOGY IN FRUIT GROWING

    Directory of Open Access Journals (Sweden)

    Z. Jurković

    2008-09-01

    Full Text Available Research studies in the area of biotechnologies in fruit growing started at the Agricultural Institute Osijek in 2006 with the establishment of the first experimental in vitro laboratory for micropropagation. The laboratory started an active research related to the Project "Biotechnological methods in fruit tree identification, selection and propagation" Project is part of program "Preservation and revitalization of grape and fruit autochthonous cultivars". The goal of this research is to determine genetic differences between autochthonous and introduced cultivars of cherry as well as cultivars and types of sour cherry, to find and optimize a method for fast recovery of clonal material. A great number of cherry cultivars and types within the population of cv. Oblacinska sour cherry exists in Croatia. A survey with the purpose of selecting autochthonous cultivars for further selection has been done in previous research. Differences have been found in a number of important agronomic traits within the populations of cv. Oblačinska sour cherry. Autochthonous cherry cultivars are suspected to be synonyms of known old cultivars which were introduced randomly and have been naturalized under a local name. Identification and description of cultivars and types of fruits is based on special visible properties which were measurable or notable. In this approach difficulties arise from the effect of non-genetic factors on expression of certain traits. Genetic-physiological problem of S allele autoincompatibility exists within cherry cultivars. Therefore it is necessary to put different cultivars in the plantation to pollinate each other. Apart form the fast and certain sort identification independent of environmental factors, biotechnological methods based on PCR enable faster virus detection compared with classical serologic methods and indexing and cover a wider range of plant pathogens including those undetectable by other methods. Thermotherapy and

  17. 76 FR 38348 - Notice of Appointment of Committee Members to the Advisory Committee on Biotechnology and 21st...

    Science.gov (United States)

    2011-06-30

    ... Advisory Committee on Biotechnology and 21st Century Agriculture AGENCY: Office of the Under Secretary... Advisory Committee on Biotechnology and 21st Century Agriculture. SUMMARY: The Office of the Under... Committee on Biotechnology and 21st Century Agriculture (``AC21''). FOR FURTHER INFORMATION CONTACT:...

  18. White biotechnology: ready to partner and invest in.

    Science.gov (United States)

    Kircher, Manfred

    2006-01-01

    It needs three factors to build an industry: market demand, product vision and capital. White biotechnology already produces high volume products such as feed additive amino acids and specialty products like enzymes for enantioselective biocatalysis. It serves large and diverse markets in the nutrition, wellness, pharmaceutical, agricultural and chemical industry. The total volume adds up to $ 50 billion worldwide. In spite of its proven track record, white biotechnology so far did not attract as much capital as red and even green biotechnology. However, the latest finance indicators confirm the continuously growing attractiveness of investment opportunities in white biotechnology. This article discusses white biotechnology's position and potential in the finance market and success factors.

  19. Biotechnology Industry

    Science.gov (United States)

    2007-01-01

    Countries Growing GMO , 2007). Herbicide and insect resistance traits will continue to be pursued since 25% of food crops are lost each year to insect...daily lives from the clothing we wear, the fuel we use, the food we eat, and the medicines we take. From the earliest days, humans have used the...industry is very broad and includes health care, food , agriculture, industrial, and environmental industries. It is one of the fastest growing sciences

  20. Biotechnology organizations in action

    DEFF Research Database (Denmark)

    Norus, Jesper

    This volume analyzes the dynamics and interactive processes among the players (individuals, institutions, and organizations/firms) that have constituted and legitimized the development of the biotechnology industries. The unit of analysis is small entrepreneurial firms developing biotechnological...

  1. Progress towards the 'Golden Age' of biotechnology.

    Science.gov (United States)

    Gartland, K M A; Bruschi, F; Dundar, M; Gahan, P B; Viola Magni, M p; Akbarova, Y

    2013-07-01

    Biotechnology uses substances, materials or extracts derived from living cells, employing 22 million Europeans in a € 1.5 Tn endeavour, being the premier global economic growth opportunity this century. Significant advances have been made in red biotechnology using pharmaceutically and medically relevant applications, green biotechnology developing agricultural and environmental tools and white biotechnology serving industrial scale uses, frequently as process feedstocks. Red biotechnology has delivered dramatic improvements in controlling human disease, from antibiotics to overcome bacterial infections to anti-HIV/AIDS pharmaceuticals such as azidothymidine (AZT), anti-malarial compounds and novel vaccines saving millions of lives. Green biotechnology has dramatically increased food production through Agrobacterium and biolistic genetic modifications for the development of 'Golden Rice', pathogen resistant crops expressing crystal toxin genes, drought resistance and cold tolerance to extend growth range. The burgeoning area of white biotechnology has delivered bio-plastics, low temperature enzyme detergents and a host of feedstock materials for industrial processes such as modified starches, without which our everyday lives would be much more complex. Biotechnological applications can bridge these categories, by modifying energy crops properties, or analysing circulating nucleic acid elements, bringing benefits for all, through increased food production, supporting climate change adaptation and the low carbon economy, or novel diagnostics impacting on personalized medicine and genetic disease. Cross-cutting technologies such as PCR, novel sequencing tools, bioinformatics, transcriptomics and epigenetics are in the vanguard of biotechnological progress leading to an ever-increasing breadth of applications. Biotechnology will deliver solutions to unimagined problems, providing food security, health and well-being to mankind for centuries to come.

  2. State FFA Officers' Confidence and Trustworthiness of Biotechnology Information Sources

    Science.gov (United States)

    Wingenbach, Gary J.; Rutherford, Tracy A.

    2007-01-01

    Are state FFA officers' awareness levels of agricultural topics reported in mass media superior to those who do not serve in leadership roles? The purpose of this study was to determine elected state FFA officers' awareness of biotechnology, and their confidence and trust of biotechnology information sources. Descriptive survey methods were used…

  3. Sectoral Innovation Watch Biotechnology Sector. Final sector report

    NARCIS (Netherlands)

    Enzing, C.

    2011-01-01

    Biotechnology has evolved from a single set of technologies in the mid 1970s into a full grown technological field that is the driving force in innovation processes in many industrial sectors (pharmaceutical, medical, agriculture, food, chemical, environment, instruments). Nowadays, biotechnology is

  4. Department of Agriculture

    Science.gov (United States)

      Topics Animal Health Biotechnology Climate Solutions Conservation Disaster and Emergency Preparedness Employee Services Energy Environment and Natural Resources Ethics Farm Bill Food and Nutrition Food Safety Forestry Housing Assistance Laws and Regulations Organic Agriculture ...

  5. Energy Crop and Biotechnology for Biofuel Production

    Institute of Scientific and Technical Information of China (English)

    Liangcai Peng; Neal Gutterson

    2011-01-01

    @@ Selection of energy crops is the first priority for large-scale biofuel production in China.As a major topic, it was extensively discussed in the Second International Symposium on Bioenergy and Biotechnology, held from October 16-19(th), 2010 in Huazhong Agricultural University(HZAU), Wuhan, China, with more than one hundred registered participants(Figure 1).

  6. A capital market's view on Industrial Biotechnology:proper valuation is the key for picking the right investment opportunities in stormy times

    OpenAIRE

    Schneider, B.W. (Bernd)

    2009-01-01

    Industrial biotechnology, also known as white biotechnology, is considered to be a revolutionary biotechnology field beside red and green biotechnology. After red (medicine) and green (agriculture), white biotechnology is now gaining momentum. With numerous applications e.g. in biocatalysis and fermentation technology, white biotech companies are able to produce – often from biomass out of agricultural products - biobased chemicals (like vitamins, amino acids or enzymes for textile finishing ...

  7. Insect Cell Culture and Biotechnology

    Institute of Scientific and Technical Information of China (English)

    Robert R.Granados; Guoxun Li; G.W.Blissard

    2007-01-01

    The continued development of new cell culture technology is essential for the future growth and application of insect cell and baculovirus biotechnology. The use of cell lines for academic research and for commercial applications is currently dominated by two cell lines; the Spodoptera frugiperda line, SF21 (and its clonal isolate, SF9), and the Trichoplusia ni line, BTI 5B1-4, commercially known as High Five cells. The long perceived prediction that the immense potential application of the baculovirus-insect cell system, as a tool in cell and molecular biology, agriculture, and animal health, has been achieved. The versatility and recent applications of this popular expression system has been demonstrated by both academia and industry and it is clear that this cell-based system has been widely accepted for biotechnological applications. Numerous small to midsize startup biotechnology companies in North America and the Europe are currently using the baculovirus-insect cell technology to produce custom recombinant proteins for research and commercial applications. The recent breakthroughs using the baculovirus-insect cell-based system for the development of several commercial products that will impact animal and human health will further enhance interest in this technology by pharma. Clearly, future progress in novel cell and engineering advances will lead to fundamental scientific discoveries and serve to enhance the utility and applications of this baculovirus-insect cell system.

  8. Biotechnology: A Dutch perspective

    NARCIS (Netherlands)

    Van Apeldoorn, J.H.F.

    1981-01-01

    Biotechnology: a Dutch Perspective assesses the future potential of biotechnology in the Netherlands. It has been published in English because it is felt that the Dutch case could be of relevance to other industrialised nations. Although the report is aimed primarily at policy planners and decision

  9. Organisation of biotechnological information into knowledge.

    Science.gov (United States)

    Boh, B

    1996-09-01

    The success of biotechnological research, development and marketing depends to a large extent on the international transfer of information and on the ability to organise biotechnology information into knowledge. To increase the efficiency of information-based approaches, an information strategy has been developed and consists of the following stages: definition of the problem, its structure and sub-problems; acquisition of data by targeted processing of computer-supported bibliographic, numeric, textual and graphic databases; analysis of data and building of specialized in-house information systems; information processing for structuring data into systems, recognition of trends and patterns of knowledge, particularly by information synthesis using the concept of information density; design of research hypotheses; testing hypotheses in the laboratory and/or pilot plant; repeated evaluation and optimization of hypotheses by information methods and testing them by further laboratory work. The information approaches are illustrated by examples from the university-industry joint projects in biotechnology, biochemistry and agriculture.

  10. Consumer demand for information about agricultural biotechnology

    DEFF Research Database (Denmark)

    Scholderer, Joachim; Czienskowski, Uwe

    The aim of the study was to provide a realistic assessment of (a) the amount and type of information that consumers would use in choices between second-generation novel foods and different types of competitor products, (b) the amount and type of information that consumers would access from genera...

  11. Biotechnology Assisted Wheat Breeding for Organic Agriculture

    DEFF Research Database (Denmark)

    Steffan, Philipp Matthias

    Common bunt of wheat is a major seed borne disease of wheat worldwide. It is of particular importance to organic farming, where systemic fungicides cannot be applied. The knowledge about location and mechanisms of common bunt resistance in wheat is limited, and only three race specific genes have...

  12. Biotechnology in Agriculture and Forestry: Economic Perspectives

    NARCIS (Netherlands)

    Kooten, van G.C.

    2011-01-01

    Economists are rarely brought into the interdisciplinary research until the biophysical scientists have developed their models, made their measurements or completed their research task. The research economist is then brought in to do what amounts to a consulting task – provide some numbers that indi

  13. Modern Biotechnology in China

    Science.gov (United States)

    Wang, Qing-Zhao; Zhao, Xue-Ming

    In recent years, with the booming economy, the Chinese government has increased its financial input to biotechnology research, which has led to remarkable achievements by China in modern biotechnology. As one of the key parts of modern biotechnology, industrial biotechnology will be crucial for China's sustainable development in this century. This review presents an overview of Chinese industrial biotechnology in last 10 years. Modern biotechnology had been classified into metabolic engineering and systems biology framework. Metabolic engineering is a field of broad fundamental and practical concept so we integrated the related technology achievements into the real practices of many metabolic engineering cases, such as biobased products production, environmental control and others. Now metabolic engineering is developing towards the systems level. Chinese researchers have also embraced this concept and have contributed invaluable things in genomics, transcriptomics, proteomics and related bioinformatics. A series of advanced laboratories or centers were established which will represent Chinese modern biotechnology development in the near future. At the end of this review, metabolic network research advances have also been mentioned.

  14. Corporate intelligence in biotechnology.

    Science.gov (United States)

    Persidis

    1999-05-01

    'Know thy neighbor' is a critical component of today's biotechnology practice. The industry is extremely rich in science and business information, and the pace of change is dramatic. Successful participation in biotechnology will always depend on good technology, management and money. In addition, an ingredient that needs more attention is competitive information- gathering and analysis. Competitive intelligence can be defined as actionable information that requires the ability to filter and synthesize relevant knowledge for the benefit of the company. Why is this necessary? How can it be done well? What examples are there? These are good questions that are inevitably faced by all biotechnology practitioners, and some answers are provided herein.

  15. Proteomics: A Biotechnology Tool for Crop Improvement

    Directory of Open Access Journals (Sweden)

    Moustafa eEldakak

    2013-02-01

    Full Text Available A sharp decline in the availability of arable land and sufficient supply of irrigation water along with a continuous steep increase in food demands have exerted a pressure on farmers to produce more with fewer resources. A viable solution to release this pressure is to speed up the plant breeding process by employing biotechnology in breeding programs. The majority of biotechnological applications rely on information generated from various -omic technologies. The latest outstanding improvements in proteomic platforms and many other but related advances in plant biotechnology techniques offer various new ways to encourage the usage of these technologies by plant scientists for crop improvement programs. A combinatorial approach of accelerated gene discovery through genomics, proteomics, and other associated -omic branches of biotechnology, as an applied approach, is proving to be an effective way to speed up the crop improvement programs worldwide. In the near future, swift improvements in -omic databases are becoming critical and demand immediate attention for the effective utilization of these techniques to produce next-generation crops for the progressive farmers. Here, we have reviewed the recent advances in proteomics, as tools of biotechnology, which are offering great promise and leading the path towards crop improvement for sustainable agriculture.

  16. Changing Climate Is Affecting Agriculture in the U.S.

    Medline Plus

    Full Text Available ... of Agriculture Main navigation Home Topics Topics Animals Biotechnology Climate Solutions Conservation Data Disaster Farming Food and ... Breadcrumb Home Topics Climate Solutions Secondary Navigation Animals Biotechnology Climate Solutions Conservation Data Disaster Farming Food and ...

  17. Biotechnology for renewable chemicals

    DEFF Research Database (Denmark)

    Borodina, Irina; Kildegaard, Kanchana Rueksomtawin; Jensen, Niels Bjerg

    2014-01-01

    The majority of the industrial organic chemicals are derived from fossil sources. With the oil and gas resources becoming limiting, biotechnology offers a sustainable alternative for production ofchemicals from renewable feedstocks. Yeast is an attractive cell factory forsustainable production...

  18. Traditional Chinese Biotechnology

    Science.gov (United States)

    Xu, Yan; Wang, Dong; Fan, Wen Lai; Mu, Xiao Qing; Chen, Jian

    The earliest industrial biotechnology originated in ancient China and developed into a vibrant industry in traditional Chinese liquor, rice wine, soy sauce, and vinegar. It is now a significant component of the Chinese economy valued annually at about 150 billion RMB. Although the production methods had existed and remained basically unchanged for centuries, modern developments in biotechnology and related fields in the last decades have greatly impacted on these industries and led to numerous technological innovations. In this chapter, the main biochemical processes and related technological innovations in traditional Chinese biotechnology are illustrated with recent advances in functional microbiology, microbial ecology, solid-state fermentation, enzymology, chemistry of impact flavor compounds, and improvements made to relevant traditional industrial facilities. Recent biotechnological advances in making Chinese liquor, rice wine, soy sauce, and vinegar are reviewed.

  19. BIOTECHNOLOGY BIOPRODUCTS "HEALING-1"

    OpenAIRE

    S. I. Artiukhova; T. T. Tolstoguzova

    2014-01-01

    Summary. The article presents data on the development of technology and qualitative research, bio-products «Healing-1». One of the promising directions in food biotechnology is the development of new integrated starter-based consortia of microorganisms, which have higher activity compared with cultures prepared using pure cultures. So it was interesting studies on the development of new biotechnology and bio-based microbial consortium of lactic acid bacteria. Based on the analysis of biotechn...

  20. Patent activity in biotechnology

    OpenAIRE

    Ekaterina, Streltsova

    2014-01-01

    Biotechnologies are a priority area of development due to the scope of global challenges and social problems they help to resolve. There is demand for updated information about the the current state of research and challenges faced. This paper discusses the potential of patent analysis and surveys the Russian biotechnological market with both quantitative and qualitative methods. It reviews key statistical and analytical findings of empirical research. The main finding is that the Russian bio...

  1. Trends in food biotechnology

    OpenAIRE

    Ramón, Daniel

    2014-01-01

    For thousands of years man has been applying genetics to improve both foodstuffs and food products. Using selective breeding and/or spontaneous mutations, a large number of plant varieties, animal breeds and microbial strains have been produced. In fact, food biotechnology is the oldest form of biotechnology. Recently, recombinant DNA techniques have been applied in food technology, creating so-called ‘genetically modified foods’ (GM foods). Examples include transgenic potatoes able to act as...

  2. BIOTECHNOLOGY : AN OVERVIEW

    Directory of Open Access Journals (Sweden)

    John I. Bruce

    2012-09-01

    Full Text Available Biotechnology as a science includes various aspects of the management and manipulation of biological systems. Recent advances in immunology, molecular biology, cell culture and other associated areas provide an opportunity for scientists to move biology out of the laboratory and into the realms of society. This has many implications which mankind on a whole may not be prepared to cope with at this time. This new capability has been referred to as "Biotechnology". Biotechnology has also been defined as "the integrated use of biochemistry, microbiology, and chemical engineering in order to achieve the capacities of microbes and culture cells". Genetic engineering which includes gene splicing and recombinant DNA-cloning is an example of a recent offshoot of biotechnology. Because of the advent of biotechnology, one can now think of the prospect of engineering tomorrows vaccines. In the past, vaccine development has been laborious and in many instances an unrewarding task. After years of effort only a handful of safe, effective vaccines have emerged. In the biotechnology arena, new methodologies and strategies for immunizing humans and domestic animals against infectious diseases are providing new hope for discovering successful vaccines. While most of the effort in the past has focused on viral vaccine development, attention is now being directed towards vaccines for protection against parasitic diseases. Currently, considerable effort is being made to develop vaccines for malaria, coccidiosis (in fowl, cholera, malaria, schistosomiasis and trypanosomiasis among others.

  3. Food biotechnology: benefits and concerns.

    Science.gov (United States)

    Falk, Michael C; Chassy, Bruce M; Harlander, Susan K; Hoban, Thomas J; McGloughlin, Martina N; Akhlaghi, Amin R

    2002-06-01

    Recent advances in agricultural biotechnology have highlighted the need for experimental evidence and sound scientific judgment to assess the benefits and risks to society. Nutrition scientists and other animal biologists need a balanced understanding of the issues to participate in this assessment. To date most modifications to crop plants have benefited producers. Crops have been engineered to decrease pesticide and herbicide usage, protect against stressors, enhance yields and extend shelf life. Beyond the environmental benefits of decreased pesticide and herbicide application, consumers stand to benefit by development of food crops with increased nutritional value, medicinal properties, enhanced taste and esthetic appeal. There remains concern that these benefits come with a cost to the environment or increased risk to the consumer. Most U.S. consumers are not aware of the extent that genetically modified foods have entered the marketplace. Consumer awareness of biotechnology seems to have increased over the last decade, yet most consumers remain confused over the science. Concern over the impact on the safety of the food supply remains low in the United States, but is substantially elevated in Europe. Before a genetically engineered crop is introduced into commerce it must pass regulatory scrutiny by as many as four different federal regulatory bodies to ensure a safe food supply and minimize the risk to the environment. Key areas for more research are evaluation of the nutritional benefits of new crops, further investigation of the environmental impact, and development of better techniques to identify and track genetically engineered products.

  4. Biotechnology worldwide and the 'European Biotechnology Thematic Network' Association (EBTNA).

    Science.gov (United States)

    Bruschi, F; Dundar, M; Gahan, P B; Gartland, K; Szente, M; Viola-Magni, M P; Akbarova, Y

    2011-09-01

    The European Biotechnology Congress 2011 held under the auspices of the European Biotechnology Thematic Network Association (EBTNA) in conjunction with the Turkish Medical Genetics Association brings together a broad spectrum of biotechnologists from around the world. The subsequent abstracts indicate the manner in which biotechnology has permeated all aspects of research from the basic sciences through to small and medium enterprises and major industries. The brief statements before the presentation of the abstracts aim to introduce not only Biotechnology in general and its importance around the world, but also the European Biotechnology Thematic Network Association and its aims especially within the framework of education and ethics in biotechnology.

  5. Ergot: from witchcraft to biotechnology.

    Science.gov (United States)

    Haarmann, Thomas; Rolke, Yvonne; Giesbert, Sabine; Tudzynski, Paul

    2009-07-01

    The ergot diseases of grasses, caused by members of the genus Claviceps, have had a severe impact on human history and agriculture, causing devastating epidemics. However, ergot alkaloids, the toxic components of Claviceps sclerotia, have been used intensively (and misused) as pharmaceutical drugs, and efficient biotechnological processes have been developed for their in vitro production. Molecular genetics has provided detailed insight into the genetic basis of ergot alkaloid biosynthesis and opened up perspectives for the design of new alkaloids and the improvement of production strains; it has also revealed the refined infection strategy of this biotrophic pathogen, opening up the way for better control. Nevertheless, Claviceps remains an important pathogen worldwide, and a source for potential new drugs for central nervous system diseases.

  6. Colloids in Biotechnology

    CERN Document Server

    Fanun, Monzer

    2010-01-01

    Colloids have come a long way from when Thomas Graham coined the term colloid to describe 'pseudo solutions'. This book enables scientists to close the gap between extensive research and translation into commercial options in biomedicine and biotechnology. It covers biosurfactants and surface properties, phase behavior, and orientational change of surfactant mixtures with peptides at the interface. It also covers adsorption of polymers and biopolymers on the surface and interface, discusses colloidal nanoparticles and their use in biotechnology, and delves into bioadhesion and microencapsulati

  7. Agave biotechnology: an overview.

    Science.gov (United States)

    Nava-Cruz, Naivy Y; Medina-Morales, Miguel A; Martinez, José L; Rodriguez, R; Aguilar, Cristóbal N

    2015-01-01

    Agaves are plants of importance both in Mexican culture and economy and in other Latin-American countries. Mexico is reported to be the place of Agave origin, where today, scientists are looking for different industrial applications without compromising its sustainability and preserving the environment. To make it possible, a deep knowledge of all aspects involved in production process, agro-ecological management and plant biochemistry and physiology is required. Agave biotechnology research has been focusing on bio-fuels, beverages, foods, fibers, saponins among others. In this review, we present the advances and challenges of Agave biotechnology.

  8. Advances in reproductive biotechnologies.

    Science.gov (United States)

    Choudhary, K K; Kavya, K M; Jerome, A; Sharma, R K

    2016-04-01

    In recent times, reproductive biotechnologies have emerged and started to replace the conventional techniques. It is noteworthy that for sustained livestock productivity, it is imperative to start using these techniques for facing the increasing challenges for productivity, reproduction and health with impending environment conditions. These recent biotechniques, both in male and female, have revolutionized and opened avenues for studying and manipulating the reproductive process both in vitro and in vivo in various livestock species for improving tis efficiency. This review attempts to highlight pros and cons, on the recent developments in reproductive biotechnologies, both in male and female in livestock species.

  9. Disclosing Biology Teachers' Beliefs about Biotechnology and Biotechnology Education

    Science.gov (United States)

    Fonseca, Maria Joao; Costa, Patricio; Lencastre, Leonor; Tavares, Fernando

    2012-01-01

    Teachers have been shown to frequently avoid addressing biotechnology topics. Aiming to understand the extent to which teachers' scarce engagement in biotechnology teaching is influenced by their beliefs and/or by extrinsic constraints, such as practical limitations, this study evaluates biology teachers' beliefs about biotechnology and…

  10. National Center for Biotechnology Information

    Science.gov (United States)

    ... to NCBI Sign Out NCBI National Center for Biotechnology Information Search database All Databases Assembly BioProject BioSample ... Search Welcome to NCBI The National Center for Biotechnology Information advances science and health by providing access ...

  11. Biotechnologies and Human Dignity

    Science.gov (United States)

    Sweet, William; Masciulli, Joseph

    2011-01-01

    In this article, the authors review some contemporary cases where biotechnologies have been employed, where they have had global implications, and where there has been considerable debate. The authors argue that the concept of dignity, which lies at the center of such documents as the 2005 Universal Declaration on Bioethics and Human Rights, the…

  12. Biotechnological Innovations in Aquaculture

    Directory of Open Access Journals (Sweden)

    Mangesh M. Bhosale

    2016-04-01

    Full Text Available Aquaculture is gaining commendable importance to meet the required protein source for ever increasing human population. The aquaculture industry is currently facing problems on developing economically viable production systems by reducing the impact on environment. Sustainable and enhanced fish production from aquaculture may be better achieved through application of recent biotechnological innovations. Utilisation of transgenic technology has led to production of fishes with faster growth rate with disease resistance. The full advantage of this technology could not be achieved due to concern of acceptance for Genetically Modified Organisms (GMOs. The biotechnological intervention in developing plant based feed ingredient in place of fish meal which contain high phosphorus is of prime area of attention for fish feed industry. The replacement of fish meal will also reduce fish feed cost to a greater extent. Year round fish seed production of carps through various biotechnological interventions is also need of the hour. This paper discusses technical, environmental and managerial considerations regarding the use of these biotechnological tools in aquaculture along with the advantages of research application and its commercialization.

  13. Biotechnology in weed control

    Science.gov (United States)

    Biotechnology can be used to enhance the management of weeds in several ways. Crops have been made resistant to herbicides by inserting transgenes that impart herbicide resistance into the plant genome. Glyphosate and glufosinate-resistant crops are commercialized in North America and crops made res...

  14. TSCA Biotechnology Notifications Status

    Science.gov (United States)

    This Notifications Table lists only those submissions received under the Biotechnology Regulation, beginning in 1998. From the Table, you can link to a brief summary of select submission and, in many cases, to a fact sheet on the decision reached by OPPT.

  15. State responses to biotechnology.

    Science.gov (United States)

    Harris, Rebecca C

    2015-01-01

    This article reviews biotechnology legislation in the 50 states for 11 policy areas spanning 1990-2010, an era of immense growth in biotechnology, genetic knowledge, and significant policy development. Policies regarding health insurance, life insurance, long-term care insurance, DNA data bank collection, biotech research protection, biotech promotion and support, employment discrimination, genetic counselor licensing, human cloning, and genetic privacy each represent major policy responses arising from biotechnology and coinciding with key areas of state regulation (insurance, criminal justice, economic development, labor law, health and safety, privacy, and property rights). This analysis seeks to answer three questions regarding biotechnology legislation at the state level: who is acting (policy adoption), when is policy adopted (policy timing), and what is policy doing (policy content). Theoretical concerns examine state ideology (conservative or liberal), policy type (economic or moral), and the role of external events (federal law, news events, etc.) on state policy adoption. Findings suggest ideological patterns in adoption, timing, and content of biotech policy. Findings also suggest economic policies tend to be more uniform in content than moral policies, and findings also document a clear link between federal policy development, external events, and state policy response.

  16. Biotechnological applications of bacterial cellulases

    Directory of Open Access Journals (Sweden)

    Esther Menendez

    2015-08-01

    Full Text Available Cellulases have numerous applications in several industries, including biofuel production, food and feed industry, brewing, pulp and paper, textile, laundry, and agriculture.Cellulose-degrading bacteria are widely spread in nature, being isolated from quite different environments. Cellulose degradation is the result of a synergic process between an endoglucanase, an exoglucanase and a,β-glucosidase. Bacterial endoglucanases degrade ß-1,4-glucan linkages of cellulose amorphous zones, meanwhile exoglucanases cleave the remaining oligosaccharide chains, originating cellobiose, which is hydrolyzed by ß-glucanases. Bacterial cellulases (EC 3.2.1.4 are comprised in fourteen Glycosil Hydrolase families. Several advantages, such as higher growth rates and genetic versatility, emphasize the suitability and advantages of bacterial cellulases over other sources for this group of enzymes. This review summarizes the main known cellulolytic bacteria and the best strategies to optimize their cellulase production, focusing on endoglucanases, as well as it reviews the main biotechnological applications of bacterial cellulases in several industries, medicine and agriculture.

  17. Challenge of Biotechnology (Review Paper

    Directory of Open Access Journals (Sweden)

    Malcolm R. Dando

    2001-10-01

    Full Text Available The unravelling of the human genetic code whose first draft was announced in June 2000 has rightly blood been hailed as a momentous achievement, opening thc book of life, certain to be the dominant technology of the 21st century, which will inform all about medicine and biology. and lead us to a total understanding of life. Simultaneously, concerns have been expressed about thc implications of this work. In the past, major new technologies have been used intensively for hostile purposes. What is thc challenge that biotechnology poses in this regard'? This review paper looks at the enormous changes in civil society that thc genomics revolution could bring. Against this background, thc growing concerns about its potential misuses have been reviewed. Thc strengths and weaknesses or the Biological and Toxin Weapons Convention (BTWC are then touched upon. The BTWC presently lacks an adequate verification mechanism. Although biotechnology has been used by human beings since prehistoric times (eg. making of bread. cheese. wines its scientific understanding came only in the latter part of the 19th century. Thc decisive turning point in the field came in the 1970s with the advent of genetic engineering. In the military context classical agents like anthrax and toxin remain the threat today. Although thc current level or sophistication for many biological agents is low, there is enormous potential for making more sophisticated weapons. It might be possible to specifically target the genetic makeup of different ethnic groups. The limited varieties of staple crops and the limited strains of modern animals make agriculture particularly open to attack. Another serious possibility is the impact of genomics in neuroscience. With a better understanding of cellular receptor systems and bioregulators, it is not inconceivable that new means would be evolved for disturbing the functions of the nervous system. Thc genomics revolution can be used for peaceful purposes

  18. Biotechnology action programme BAP 1985-1989. Progress report 1987. Vol. 1. An overview

    Energy Technology Data Exchange (ETDEWEB)

    Magnien, E. (ed.)

    1987-01-01

    The multiannual research and training programme of the European Economic Community in the field of biotechnology is presented. It deals with two essential tasks, namely the establishment of a supportive infrastructure for biotechnology research and development in Europe as well as the exploitation by industry and agriculture of the materials and methods originating from modern biology. (EF)

  19. Elemental analysis in biotechnology.

    Science.gov (United States)

    Hann, Stephan; Dernovics, Mihaly; Koellensperger, Gunda

    2015-02-01

    This article focuses on analytical strategies integrating atomic spectroscopy in biotechnology. The rationale behind developing such methods is inherently linked to unique features of the key technique in elemental analysis, which is inductively coupled plasma mass spectrometry: (1) the high sensitivity and selectivity of state of the art instrumentation, (2) the possibility of accurate absolute quantification even in complex matrices, (3) the capability of combining elemental detectors with chromatographic separation methods and the versatility of the latter approach, (4) the complementarity of inorganic and organic mass spectrometry, (5) the multi-element capability and finally (6) the capability of isotopic analysis. The article highlights the most recent bio-analytical developments exploiting these methodological advantages and shows the potential in biotechnological applications.

  20. Electron shuttles in biotechnology.

    Science.gov (United States)

    Watanabe, Kazuya; Manefield, Mike; Lee, Matthew; Kouzuma, Atsushi

    2009-12-01

    Electron-shuttling compounds (electron shuttles [ESs], or redox mediators) are essential components in intracellular electron transfer, while microbes also utilize self-produced and naturally present ESs for extracellular electron transfer. These compounds assist in microbial energy metabolism by facilitating electron transfer between microbes, from electron-donating substances to microbes, and/or from microbes to electron-accepting substances. Artificially supplemented ESs can create new routes of electron flow in the microbial energy metabolism, thereby opening up new possibilities for the application of microbes to biotechnology processes. Typical examples of such processes include halogenated-organics bioremediation, azo-dye decolorization, and microbial fuel cells. Herein we suggest that ESs can be applied widely to create new microbial biotechnology processes.

  1. BIOTECHNOLOGY BIOPRODUCTS "HEALING-1"

    Directory of Open Access Journals (Sweden)

    S. I. Artiukhova

    2014-01-01

    Full Text Available Summary. The article presents data on the development of technology and qualitative research, bio-products «Healing-1». One of the promising directions in food biotechnology is the development of new integrated starter-based consortia of microorganisms, which have higher activity compared with cultures prepared using pure cultures. So it was interesting studies on the development of new biotechnology and bio-based microbial consortium of lactic acid bacteria. Based on the analysis of biotechnological properties of native cultures created a new consortium of microorganisms containing lactic acid streptococci and bacilli, allowing the maximum extent possible to implement the physiological, biochemical and technological potential of microorganisms. Scientifically substantiated and experimentally developed a new biotechnology production of bioproducts «Healing-1», obtained on the basis of microbial consortium with broad spectrum antimicrobial activity. Experimentally investigated quality parameters of organic food «Healing-1» using a new microbial consortium as freshly prepared and during storage. Found that antagonistic activity of microflora bio «Healing-1» with respect to pathogenic and conditionally pathogenic bacteria, as well as its resistance to substances in the gastrointestinal tract of man is more pronounced compared to bioproducts obtained using a separate starter, members of the microbial consortium. It should be noted a more pronounced synthesis of exopolysaccharides in bioproduct «Healing-1», which leads to increased viscosity of the system and improves the consistency of bio. New bioproducts have good organoleptic characteristics and contain a high number of viable cells of lactic acid bacteria. High stability and survival of lactic acid bacteria during storage. In the study of attacked proteins bioproducts digestive proteinases «in vitro» found that the fermentation of milk microbial consortium increases the digestibility

  2. Biotechnology and Composite Materials

    Science.gov (United States)

    1993-04-01

    Biotechnology, in general terms, is the science and engineering of using living organisms for making useful products such as pharmaceuticals, foods , fuels...chemicals, materials or in waste treatment processes and clinical and chemical analyses. It encompases the prosaic form of using yeast cells to make...ductile component of the composite. Table 1. Mechanical Properties of Ceramics, Cermets, and Abalone Shell •if KIC Hardness MPa MPam 1n 2 /2 Mohs KIlN

  3. Practicing environmental biotechnology

    Directory of Open Access Journals (Sweden)

    Bruce E.Rittmann

    2014-02-01

    Full Text Available Environmental biotechnology involves ″managing microbial communities to provide services to society″.Its success comes from partnering with prokaryotic microorganisms,whose wide ranging metabolic capabilities can be harnessed to destroy pollutants and to generate renewable materials.Partnering with microorganisms requires that we understand them well,and important advances in molecular microbial ecology,analytical chemistry,and mathematical modeling are making it possible to look inside the black box of microbial communities.Also crucial is translating the understanding to biotechnological processes that ″work for the microorganisms so that they work for us″.Successful translation demands novel reactor designs,application of advanced materials,and partnering with practitioners and users.The Swette Center for Environmental Biotechnology,founded in at Arizona State University in 2005,brings together the science and engineering tools in an inter disciplinary environment.The Center emphasizes teamwork and collaborations with research and practice partners around the world.Three new technologies illustrate how the Center applies these principles to ″work for the microorganisms″:the H2-based membrane biofilm reactor (MBfR for reducing many oxidized contaminants in water,the microbial electrochemical cells (MXCs for converting organic wastes into renewable products,and Intimately Coupled PhotoBioCatalysis (ICPBC to detoxify very difficult to biodegrade organic pollutants.

  4. Biotechnology: reality or dream

    Directory of Open Access Journals (Sweden)

    Konstantinov Kosana

    2002-01-01

    Full Text Available The development of molecular biology and molecular genetics, especially of the recombinant DNA technology enabled improvement of experimental methods that provide manipulation within a cell-free system, such as cell and tissue cultures. Such methods resulted in the development of different new technologies with specific properties in relation to the conventional definitions. According to PERSLEY and lantin (2000 the following components are essential for the contemporary biotechnology: (i genomics - a molecular characterization of all genes and gene products of an organism (ii bioinformatics - the assembly of data from genomic analysis into accessible forms; (iii transformation - the introduction of genes controlling a trait of interest into a genome of a desired organism (micro organisms, plants, animal systems. By the application of cotemporary biotechnology new methods in the field of diagnostic are developed such as rapid and more accurate identification of the presence and absence of genes in the genome of the organism of interest (identification of pathogens prenatal diagnostics, molecular markers assisted breeding for plants, etc. The traits of an organism are determined by its genetic material, i.e. by a molecule of deoxyribonucleic acid (DNA. watson and crick (1953 were the first scientists to describe the structure of DNA as a double-stranded helix. Higher organisms contain a set of linear DNA molecules - chromosomes and a full set of chromosomes of an organism is a genome. Each genome is divided into a series of functional units, i.e. genes. The traits of an organism depend on genes, but their expression depends not only on genes but also on many other factors, including whether a gene, controlling the trait, expresses, specific cells in which it expresses and specially the mode by which the gene and its product interact with the environment. A special aspect within the application of biotechnology occurs as an interaction of a

  5. Plant biotechnology : Future perspectives (Review Paper

    Directory of Open Access Journals (Sweden)

    P. Ananda Kumar

    2001-10-01

    Full Text Available Plant biotechnology has made significant strides in thc past 15 years encompassing within its fold the spectacular developments in plant molecular biology and genetic engineering. Some of the most vexing problems faced in agricultural ecosystems could be solved with the introduction of transgenic crops endowed with traits for insect pest resistance, herbicide tolerance and resistance to viral diseases. Attention is now being focussed on the development of transgenic plants having industrial, economic, pharmaceutical, nutritional and environmental importance. In the next millennium, crops will serve as factories for the synthesis of valuable metabolites and organic compounds. Agronomically important characters, such as drought tolerance, efficiency in photosynthesis, nutrient use and nitrogen fixation will be manipulated in the next century to enhance the genetic and physiological potential of the crops. Recent developments in the genome sequencing of Arabidopsis, rice and maize will have far reaching implications for future agriculture. Structural and functional genomics of plant species will virtually revolutionise the complexion of agricultural biotechnology as well as human health care. It is imperative that the developing world adopts these fast-changing technologies soon and harness their unprecedented potential for the benefit of the mankind. "

  6. Working Towards Disease Resistance in Peanuts Through Biotechnology

    Science.gov (United States)

    Resistant cultivars are the most desirable approach to disease control in agriculture. Early and late leaf spot are the most important foliar diseases of peanut worldwide. Significant progress for leaf spot resistance in peanut can be achieved through biotechnology. The National Peanut Research ...

  7. Herbicide-resistant crop biotechnology: potential and pitfalls

    Science.gov (United States)

    Herbicide-resistant crops are an important agricultural biotechnology that can enable farmers to effectively control weeds without harming their crops. Glyphosate-resistant (i.e. Roundup Ready) crops have been the most commercially successful varieties of herbicide-resistant crops and have been plan...

  8. How biotechnology is changing the structure of the seed industry

    NARCIS (Netherlands)

    Bijman, W.J.J.

    2001-01-01

    The seed industry has been in a state of restructuring for many years now. New firms have entered the industry and old players have merged. Firms from various backgrounds now compete in supplying seed to agriculture and horticulture: Traditional seed companies, new biotechnology firms, agrochemical

  9. 依托国家基地培养农业生物技术产业化人才的探索与实践%Exploring and practicing the training of talents of agricultural biotechnology industry on the national base

    Institute of Scientific and Technical Information of China (English)

    金安江; 江珩; 郑用琏

    2015-01-01

    实现农业生物产业的健康发展必须要有源源不断的高素质人才支撑。通过华中农业大学国家生命科学与技术人才培养基地的改革实践,探讨了培养农业生物技术产业化人才的有效模式。主要体现在,坚持科学定位,以实践创新能力为核心,依托优势学科,构建“基础+方向”的人才培养体系;整合优势资源,培养“宏观+微观”的生物学实验技能;搭建创新平台,激发“生产+研发”的产业化潜能。%The steady supply of high-quality talent is very important to achieve the healthy development of agricultural biotechnolo-gy industry. This paper discussed the effective models of training the talents of agricultural biotechnology industry through reforming the practice of the national life science and technology talent training base. The models include adhering to the scientific position, practice innovation ability as the core, relying on the advantage of discipline, building the talent training system on"base and direc-tion", integrating resources, developing biological experimental skills of"macro and micro", constructing platform of innovation, and stimulating industrialization potential of"production and research".

  10. Seaweed Aquaculture and Marine Biotechnology

    OpenAIRE

    Gonçalves Pereira, Rui

    2016-01-01

    Macroscopic marine algae, typically known as macroalgae or seaweeds, form an important living resource of the oceans, as primary producers. People have collected seaweeds for food, both for humans and animals for millennia. They also have been a source of nutrient rich fertilizers, as well as a source of gelling agents known as phycocolloids. More recently macroalgae are playing significant roles in medicine and biotechnology. Although Biotechnology and in particular marine biotechnology may ...

  11. BIOTECHNOLOGY OF THE FISH AQUACULTURE

    OpenAIRE

    L. P. Buchatsky

    2013-01-01

    The latest progress in biotechnology on fish aquaculture and different modern methods of investigations for increasing of fish productivity in aquaculture are analyzed. Except for the applied aspect, the use of modern biotechnological methods of investigations opens new possibilities for fundamental researches of sex-determining mechanisms, polyploidy, distant hybridization, and developmental biology of bony fishes. Review contains examples of utilizing modern biotechnology methods to obtain ...

  12. Plant Biotechnology: Promises and Challenges

    Directory of Open Access Journals (Sweden)

    P.V. Lakshmana Rao

    1996-01-01

    Full Text Available Development of procedures in cell biology to regenerate plants from single cells in any desired quantity provides the prerequisite for the practical use of plant tissue culture and genetic engineering in crop improvement. Such regenerating cell cultures are used for selection of mutants and for DNA transformation experiments. DNA transfer by means of engineered Ti and Ri plasmids has become an established technique for the rapidly growing list of dicotyledonous plants. Considerable success has also been achieved in making gene transfer techniques independent of cell culture methods. These techniques have given the opportunity to create, characterise and select plant cultivars which cannot be obtained by traditional breeding methods. The exploitation of plant cell cultures for production of pharmaceuticals, natural products of commercial importance and mass propagation of high-value crops by automation, have developed into an important industry with considerable potential for future. This paper discusses the recent advances and applications of plant biotechnology in agriculture and industry and the challenges the still exist.

  13. Biotechnological applications of microalgae

    Directory of Open Access Journals (Sweden)

    Wan-Loy Chu

    2012-07-01

    Full Text Available Microalgae are important biologicalresources that have a wide range of biotechnologicalapplications. Due to their high nutritional value,microalgae such as Spirulina and Chlorella are beingmass cultured for health food. A variety of high-valueproducts including polyunsaturated fatty acids (PUFA,pigments such as carotenoids and phycobiliproteins, andbioactive compounds are useful as nutraceuticals andpharmaceuticals, as well as for industrial applications. Interms of environmental biotechnology, microalgae areuseful for bioremediation of agro-industrial wastewater,and as a biological tool for assessment and monitoring ofenvironmental toxicants such as heavy metals, pesticidesand pharmaceuticals. In recent years, microalgae haveattracted much interest due to their potential use asfeedstock for biodiesel production. In Malaysia, therehas been active research on microalgal biotechnologyfor the past 30 years, tapping into the potential of ourrich microalgal resources for high-value products andapplications in wastewater treatment and assessmentof environmental toxicants. A culture collection ofmicroalgae has been established, and this serves asan important resource for microalgal biotechnologyresearch. Microalgal biotechnology should continue tobe regarded as a priority area of research in this country.

  14. Biotechnology Towards Energy Crops.

    Science.gov (United States)

    Margaritopoulou, Theoni; Roka, Loukia; Alexopoulou, Efi; Christou, Myrsini; Rigas, Stamatis; Haralampidis, Kosmas; Milioni, Dimitra

    2016-03-01

    New crops are gradually establishing along with cultivation systems to reduce reliance on depleting fossil fuel reserves and sustain better adaptation to climate change. These biological assets could be efficiently exploited as bioenergy feedstocks. Bioenergy crops are versatile renewable sources with the potential to alternatively contribute on a daily basis towards the coverage of modern society's energy demands. Biotechnology may facilitate the breeding of elite energy crop genotypes, better suited for bio-processing and subsequent use that will improve efficiency, further reduce costs, and enhance the environmental benefits of biofuels. Innovative molecular techniques may improve a broad range of important features including biomass yield, product quality and resistance to biotic factors like pests or microbial diseases or environmental cues such as drought, salinity, freezing injury or heat shock. The current review intends to assess the capacity of biotechnological applications to develop a beneficial bioenergy pipeline extending from feedstock development to sustainable biofuel production and provide examples of the current state of the art on future energy crops.

  15. Advanced genetic tools for plant biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Liu, WS; Yuan, JS; Stewart, CN

    2013-10-09

    Basic research has provided a much better understanding of the genetic networks and regulatory hierarchies in plants. To meet the challenges of agriculture, we must be able to rapidly translate this knowledge into generating improved plants. Therefore, in this Review, we discuss advanced tools that are currently available for use in plant biotechnology to produce new products in plants and to generate plants with new functions. These tools include synthetic promoters, 'tunable' transcription factors, genome-editing tools and site-specific recombinases. We also review some tools with the potential to enable crop improvement, such as methods for the assembly and synthesis of large DNA molecules, plant transformation with linked multigenes and plant artificial chromosomes. These genetic technologies should be integrated to realize their potential for applications to pressing agricultural and environmental problems.

  16. Teachers' Concerns about Biotechnology Education

    Science.gov (United States)

    Borgerding, Lisa A.; Sadler, Troy D.; Koroly, Mary Jo

    2013-01-01

    The impacts of biotechnology are found in nearly all sectors of society from health care and food products to environmental issues and energy sources. Despite the significance of biotechnology within the sciences, it has not become a prominent trend in science education. In this study, we seek to more fully identify biology teachers' concerns…

  17. A Case for Teaching Biotechnology

    Science.gov (United States)

    Lazaros, Edward; Embree, Caleb

    2016-01-01

    Biotechnology is an innovative field that is consistently growing in popularity. It is important that students are taught about this technology at an early age, so they are motivated to join the field, or at least motivated to become informed citizens and consumers (Gonzalez, et al, 2013). An increase in biotechnology knowledge can result in an…

  18. Biotechnology and food systems in developing countries.

    Science.gov (United States)

    Timmer, C Peter

    2003-11-01

    Even in a world with adequate food supplies in global markets, which is the situation today, biotechnology offers important opportunities to developing countries in four domains. First, many agronomically hostile or degraded environments require major scientific breakthroughs to become productive agricultural systems. Few of these breakthroughs are likely to be achieved through traditional breeding approaches. Second, biofortification offers the promise of greater quantities and human availabilities of micronutrients from traditional staple foods, with obvious nutritional gains for poor consumers, especially their children. Third, many high yielding agricultural systems are approaching their agronomic potential. Radically new technologies will be required to sustain productivity growth in these systems, and only modern genetic technology offers this hope. Finally, many cropping systems use large quantities of chemical inputs, such as herbicides, pesticides and fertilizers that can be unhealthy for people and soils alike. Biotechnology offers the potential to reduce the need for these inputs in economically and environmentally sustainable ways. Applying these new technologies to society's basic foods raises obvious concerns for both human and ecological health. For some, these concerns have become outright fear, and this has mobilized a backlash against genetically modified foods in any form. These concerns (and fears) must be addressed carefully and rationally so that the public understands the risks (which are not zero) and benefits (which might be enormous). Only the scientific community has the expertise and credibility to build this public understanding.

  19. 韩国农业生物技术年报(2011年)%Seung-Ah Chung,Michael G. Francom,Kathryn Ting* Korea Agricultural Biotechnology Annual

    Institute of Scientific and Technical Information of China (English)

    Seung-Ah Chung; Michael G. Francom; Kathryn Ting

    2013-01-01

      韩国正在修改其法律和法规,以体现《卡塔赫纳生物安全议定书》中的最新要求以及其他国际惯例。这些修订将让新转基因成分和转基因产品贸易的审批更加可以预测和透明。消费者对转基因食品的态度开始缓和,但是负面观点仍然存在。发动本地农民支持采用和积极推广这种技术在本地种植的作物中的采用被认为是增强消费者信心的关键。%Korea is in the process of revising its laws and regulations to reflect the current language in the Cartagena Protocol on Biosafety as well as other international practices. These revisions will make the approval of new biotech events and the trade in these products more predictable and transparent. Consumer attitudes toward the use of biotechnology in food are starting to soften, but negative perceptions still persist. Generating local farmers' support to adopt and actively use this technology in locally grown crops is seen as the key to increasing consumer confidence.

  20. Biotechnology of space utilization

    Energy Technology Data Exchange (ETDEWEB)

    Matsumiya, Hiroyuki

    1989-10-05

    This paper introdued the practical results of biotechnological experiments utilizing features of space and the present Japanese plan. The electrophoresis and crystal growth of protein utilize the microgravity field and cell culture utilizes the influence of microgravity on organism. Of practical results in space experiments, the electrophoresis was made by US but others were carried out by Europian countries. It was thought that the electrophoresis utilizing space environment could be demonstrated to be promosing for the separating and refining techniques by the experiment on the basis of the Apolo Project. The crystal growth of protein was reported by Litke of Denmark as to the crystal of lyzozyme. The space experiment of cell culture was carried out by Cogoli of Switzerland as to the culture of lymphocyte in the Shattle. Japan is studying the primary material experiment project(FMPT) in the Space Shattle and unmanned experiment for electrophoresis. 9 refs., 3 tabs.

  1. Bacteriophages and their implications on future biotechnology: a review.

    Science.gov (United States)

    Haq, Irshad Ul; Chaudhry, Waqas Nasir; Akhtar, Maha Nadeem; Andleeb, Saadia; Qadri, Ishtiaq

    2012-01-10

    Recently it has been recognized that bacteriophages, the natural predators of bacteria can be used efficiently in modern biotechnology. They have been proposed as alternatives to antibiotics for many antibiotic resistant bacterial strains. Phages can be used as biocontrol agents in agriculture and petroleum industry. Moreover phages are used as vehicles for vaccines both DNA and protein, for the detection of pathogenic bacterial strain, as display system for many proteins and antibodies. Bacteriophages are diverse group of viruses which are easily manipulated and therefore they have potential uses in biotechnology, research, and therapeutics. The aim of this review article is to enable the wide range of researchers, scientists, and biotechnologist who are putting phages into practice, to accelerate the progress and development in the field of biotechnology.

  2. Bacteriophages and their implications on future biotechnology: a review

    Directory of Open Access Journals (Sweden)

    Haq Irshad

    2012-01-01

    Full Text Available Abstract Recently it has been recognized that bacteriophages, the natural predators of bacteria can be used efficiently in modern biotechnology. They have been proposed as alternatives to antibiotics for many antibiotic resistant bacterial strains. Phages can be used as biocontrol agents in agriculture and petroleum industry. Moreover phages are used as vehicles for vaccines both DNA and protein, for the detection of pathogenic bacterial strain, as display system for many proteins and antibodies. Bacteriophages are diverse group of viruses which are easily manipulated and therefore they have potential uses in biotechnology, research, and therapeutics. The aim of this review article is to enable the wide range of researchers, scientists, and biotechnologist who are putting phages into practice, to accelerate the progress and development in the field of biotechnology.

  3. Bioceres: AG Biotechnology from Argentina

    Directory of Open Access Journals (Sweden)

    Roberto Feeney

    2016-04-01

    Full Text Available In this case we present a business decision-making situation in which the CEO of an Argentine Ag Biotech company, Bioceres, has to decide the best way to commercialize a new drought-tolerant transgenic technology. The company was founded by twenty three farmers, who shared a common dream that Argentina could become a benchmark in the development of Ag biotechnology. The case has strategic and financial implications, as well as decision-making situation involving a joint venture with an American biotechnology company. It also introduces to discussion the business models of Ag biotechnology companies in developing countries.

  4. Biotechnology of non-Saccharomyces yeasts-the basidiomycetes.

    Science.gov (United States)

    Johnson, Eric A

    2013-09-01

    Yeasts are the major producer of biotechnology products worldwide, exceeding production in capacity and economic revenues of other groups of industrial microorganisms. Yeasts have wide-ranging fundamental and industrial importance in scientific, food, medical, and agricultural disciplines (Fig. 1). Saccharomyces is the most important genus of yeast from fundamental and applied perspectives and has been expansively studied. Non-Saccharomyces yeasts (non-conventional yeasts) including members of the Ascomycetes and Basidiomycetes also have substantial current utility and potential applicability in biotechnology. In an earlier mini-review, "Biotechnology of non-Saccharomyces yeasts-the ascomycetes" (Johnson Appl Microb Biotechnol 97: 503-517, 2013), the extensive biotechnological utility and potential of ascomycetous yeasts are described. Ascomycetous yeasts are particularly important in food and ethanol formation, production of single-cell protein, feeds and fodder, heterologous production of proteins and enzymes, and as model and fundamental organisms for the delineation of genes and their function in mammalian and human metabolism and disease processes. In contrast, the roles of basidiomycetous yeasts in biotechnology have mainly been evaluated only in the past few decades and compared to the ascomycetous yeasts and currently have limited industrial utility. From a biotechnology perspective, the basidiomycetous yeasts are known mainly for the production of enzymes used in pharmaceutical and chemical synthesis, for production of certain classes of primary and secondary metabolites such as terpenoids and carotenoids, for aerobic catabolism of complex carbon sources, and for bioremediation of environmental pollutants and xenotoxicants. Notwithstanding, the basidiomycetous yeasts appear to have considerable potential in biotechnology owing to their catabolic utilities, formation of enzymes acting on recalcitrant substrates, and through the production of unique primary

  5. European Union research and innovation perspectives on biotechnology.

    Science.gov (United States)

    Cichocka, Danuta; Claxton, John; Economidis, Ioannis; Högel, Jens; Venturi, Piero; Aguilar, Alfredo

    2011-12-20

    "Food, Agriculture and Fisheries and Biotechnology" is one of 10 thematic areas in the Cooperation programme of the European Union's 7th Framework Programme for Research, Technological Development and Demonstration Activities (FP7). With a budget of nearly €2 billion for the period 2007-2013, its objective is to foster the development of a European Knowledge-Based Bio-Economy (KBBE) by bringing together science, industry and other stakeholders that produce, manage or otherwise exploit biological resources. Biotechnology plays an important role in addressing social, environmental and economic challenges and it is recognised as a key enabling technology in the transition to a green, low carbon and resource-efficient economy. Biotechnologies for non-health applications have received a considerable attention in FP7 and to date 61 projects on industrial, marine, plant, environmental and emerging biotechnologies have been supported with a contribution of €262.8 million from the European Commission (EC). This article presents an outlook of the research, technological development and demonstration activities in biotechnology currently supported in FP7 within the Cooperation programme, including a brief overview of the policy context.

  6. An Overview of NASA Biotechnology

    Science.gov (United States)

    Pusey, Marc L.

    1997-01-01

    Biotechnology research at NASA has comprised three separate areas; cell science and tissue culture, separations methods, and macromolecular crystal growth. This presentation will primarily focus on the macromolecular crystal growth.

  7. Novel biocatalysts for white biotechnology.

    Science.gov (United States)

    Drepper, Thomas; Eggert, Thorsten; Hummel, Werner; Leggewie, Christian; Pohl, Martina; Rosenau, Frank; Wilhelm, Susanne; Jaeger, Karl-Erich

    2006-01-01

    White Biotechnology uses microorganisms and enzymes to manufacture a large variety of chemical products. Therefore, the demand for new and useful biocatalysts is steadily and rapidly increasing. We have developed methods for the isolation of new enzyme genes, constructed novel expression systems, and optimized existing enzymes for biotechnological applications by methods of directed evolution. Furthermore, we have isolated and characterized biocatalysts relevant for the preparation of enantiopure compounds.

  8. New Directions in Biotechnology

    Science.gov (United States)

    2003-01-01

    The macromolecule crystallization program within NASA is undergoing considerable pressure, particularly budgetary pressure. While it has shown some successes, they have not lived up to the expectations of others, and technological advances may rapidly overtake the natural advantages offered by crystallization in microgravity. Concomitant with the microgravity effort has been a research program to study the macromolecule crystallization process. It was believed that a better understanding of the process would lead to growth of improved crystals for X-ray diffraction studies. The results of the various research efforts have been impressive in improving our understanding of macromolecule crystallization, but have not led to any improved structures. Macromolecule crystallization for structure determination is "one of", the job being unique for every protein and finished once a structure is obtained. However, the knowledge gained is not lost, but instead lays the foundation for developments in new areas of biotechnology and nanotechnology. In this it is highly analogous to studies into small molecule crystallization, the results of which have led to our present day microelectronics-based society. We are conducting preliminary experiments into areas such as designed macromolecule crystals, macromolecule-inorganic hybrid structures, and macromolecule-based nanotechnology. In addition, our protein crystallization studies are now being directed more towards industrial and new approaches to membrane protein crystallization.

  9. Glutathione transferases: emerging multidisciplinary tools in red and green biotechnology.

    Science.gov (United States)

    Chronopoulou, Evangelia G; Labrou, Nikolaos E

    2009-01-01

    Cytosolic glutathione transferases (GSTs) are a diverse family of enzymes involved in a wide range of biological processes, many of which involve the conjugation of the tripeptide glutathione (GSH) to an electrophilic substrate. Detailed studies of GSTs are justified because of the considerable interest of these enzymes in medicine, agriculture and analytical biotechnology. For example, in medicine, GSTs are explored as molecular targets for the design of new anticancer drugs as a plausible means to sensitize drug-resistant tumors that overexpress GSTs. In agriculture, GSTs are exploited in the development of transgenic plants with increased resistance to biotic and abiotic stresses. Recently, selected isoenzymes of GSTs have found successful applications in the development of enzyme biosensors for the direct monitoring of environmental pollutants, such as herbicides and insecticides. This review article summarizes recent representative patents related to GSTs and their applications in biotechnology.

  10. Intellectual Property Rights and Agro-Biotechnology: Limitations and Alternatives

    Directory of Open Access Journals (Sweden)

    Mary Luz Yaya-Lancheros

    2008-11-01

    Full Text Available Intellectual property rights have led to stimulating innovation in different fields such as biotechnology. Patents, plant variety protection, industrial secrets and material transfer agreements are legal terms individually and/or collectively protecting materials or processes deemed necessary for agricultural-biotech product development. Such terms may often accumulate to such an extent that this hinders a product’s development and commercial release. Some current initiatives are aimed at facilitating access to basic technology for agricultural-biotech product development, including public organisation cooperation networks, requests for special licences for humanitarian programmes and open access projects. These may be good short-and medium-term alternatives for carrying out biotechnological research in countries like Colombia.

  11. Mannan biotechnology: from biofuels to health.

    Science.gov (United States)

    Yamabhai, Montarop; Sak-Ubol, Suttipong; Srila, Witsanu; Haltrich, Dietmar

    2016-01-01

    Mannans of different structure and composition are renewable bioresources that can be widely found as components of lignocellulosic biomass in softwood and agricultural wastes, as non-starch reserve polysaccharides in endosperms and vacuoles of a wide variety of plants, as well as a major component of yeast cell walls. Enzymatic hydrolysis of mannans using mannanases is essential in the pre-treatment step during the production of second-generation biofuels and for the production of potentially health-promoting manno-oligosaccharides (MOS). In addition, mannan-degrading enzymes can be employed in various biotechnological applications, such as cleansing and food industries. In this review, fundamental knowledge of mannan structures, sources and functions will be summarized. An update on various aspects of mannan-degrading enzymes as well as the current status of their production, and a critical analysis of the potential application of MOS in food and feed industries will be given. Finally, emerging areas of research on mannan biotechnology will be highlighted.

  12. Potential applications of insect symbionts in biotechnology.

    Science.gov (United States)

    Berasategui, Aileen; Shukla, Shantanu; Salem, Hassan; Kaltenpoth, Martin

    2016-02-01

    Symbiotic interactions between insects and microorganisms are widespread in nature and are often the source of ecological innovations. In addition to supplementing their host with essential nutrients, microbial symbionts can produce enzymes that help degrade their food source as well as small molecules that defend against pathogens, parasites, and predators. As such, the study of insect ecology and symbiosis represents an important source of chemical compounds and enzymes with potential biotechnological value. In addition, the knowledge on insect symbiosis can provide novel avenues for the control of agricultural pest insects and vectors of human diseases, through targeted manipulation of the symbionts or the host-symbiont associations. Here, we discuss different insect-microbe interactions that can be exploited for insect pest and human disease control, as well as in human medicine and industrial processes. Our aim is to raise awareness that insect symbionts can be interesting sources of biotechnological applications and that knowledge on insect ecology can guide targeted efforts to discover microorganisms of applied value.

  13. Canada. National Biotechnology Advisory Committee: Annual report 1985-1986

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    The Committee is to recommend, to the Minister of State for Science and Technology, policies and focused strategies for the continued economic growth of Canada by enhancing the international competitiveness of Canadian industry through the development, application and commercialization of biotechnology. This annual report includes a list of members, and Committee activities. It discusses research, technology transfer, precommercial development, and marketing and commercialization. Next, it looks at opportunities in agriculture, forestry and health care. Finally, the document touches on future activities.

  14. Public Acceptance of Plant Biotechnology and GM Crops

    OpenAIRE

    2015-01-01

    A wide gap exists between the rapid acceptance of genetically modified (GM) crops for cultivation by farmers in many countries and in the global markets for food and feed, and the often-limited acceptance by consumers. This review contrasts the advances of practical applications of agricultural biotechnology with the divergent paths—also affecting the development of virus resistant transgenic crops—of political and regulatory frameworks for GM crops and food in different parts of the world. T...

  15. PLANT TISSUE CULTURE IN BIOTECHNOLOGY: RECENT ADVANCES IN TRANSFORMATION THROUGH SOMATIC EMBRYOGENESIS

    Directory of Open Access Journals (Sweden)

    V. A. Sidorov

    2012-08-01

    Full Text Available Plant genetic transformation has become an important biotechnology tool for the improvement of many crops. A solid foundation for the fast development and implementation of biotechnology in agriculture was provided by achievements in plant tissue culture. On the 30th anniversary of plant transformation, I report the advancements, recent challenges and shifts in methodology of transformation. The main focus of this paper will be on conventional and novel approaches for genetic improvements of soybean, cotton and corn. I will also highlight results on the transformation of these crops that have considerably been improved by modern biotechnology.

  16. Cosmetics - chemical technology or biotechnology?

    Science.gov (United States)

    Allen, G

    1984-04-01

    Synopsis Over the past 25 years the cosmetic industry has become increasingly technological. The origins of many of these advances were based upon chemical technology usually related to colloid science, although more recent developments have had clear biological improvements. A number of recent innovations are examined to consider how far developments in the future will stem from biotechnology rather than chemical technology. The working of surface active materials (e.g. CTAB) is discussed as an example of cosmetic effects being generated purely from chemical technology. The role of fluoride toothpaste in decreasing the incidence of dental caries is discussed as an effect based essentially on chemical technology in an area where future alternatives might come from biotechnology. Skin research is highlighted as the area where new understanding, e.g. of the role of epidermal growth factor (EGF), fibronectin and laminin, could lead to a whole new biotechnological approach to the appraisal of skin. As we venture into innovations based on biotechnology we may be introducing new dimensions in product safety which will need an even closer relationship with the medical fraternity. Consequently the introduction of products based on biotechnology may not be as rapid as is sometimes suggested.

  17. Synthetic microbial ecosystems for biotechnology.

    Science.gov (United States)

    Pandhal, Jagroop; Noirel, Josselin

    2014-06-01

    Most highly controlled and specific applications of microorganisms in biotechnology involve pure cultures. Maintaining single strain cultures is important for industry as contaminants can reduce productivity and lead to longer "down-times" during sterilisation. However, microbes working together provide distinct advantages over pure cultures. They can undertake more metabolically complex tasks, improve efficiency and even expand applications to open systems. By combining rapidly advancing technologies with ecological theory, the use of microbial ecosystems in biotechnology will inevitably increase. This review provides insight into the use of synthetic microbial communities in biotechnology by applying the engineering paradigm of measure, model, manipulate and manufacture, and illustrate the emerging wider potential of the synthetic ecology field. Systems to improve biofuel production using microalgae are also discussed.

  18. Biotechnology and food allergy.

    Science.gov (United States)

    Helm, Ricki M

    2002-01-01

    The production of genetically modified foods for an increasingly informed and selective consumer requires the coordinated activities of both the companies developing the transgenic food and regulatory authorities to ensure that these foods are at least as safe as the traditional foods they are supplementing in the diet. Although the size and complexity of the food sector ensures that no single player can control the process from seed production through farming and processing to final products marketed in a retail outlet, checks and balances are in place to ensure that transgenic foods will provide a convenient, wholesome, tasty, safe, affordable food source. Ultimately, it is the responsibility of companies developing the genetically modified food to provide relevant data to regulatory agencies, such as the US Department of Agriculture, Environmental Protection Agency, and Food and Drug Administration, to confirm that the transgenic product is reasonably safe for the consumer, as zero risk from allergen sensitization is nonexistent.

  19. Past, present, and future industrial biotechnology in China.

    Science.gov (United States)

    Li, Zhenjiang; Ji, Xiaojun; Kan, Suli; Qiao, Hongqun; Jiang, Min; Lu, Dingqiang; Wang, Jun; Huang, He; Jia, Honghua; Ouyuang, Pingkai; Ying, Hanjie

    2010-01-01

    Fossil resources, i.e. concentrated carbon from biomass, have been irrecoverably exhausted through modern industrial civilization in the last two hundred years. Serious consequences including crises in resources, environment and energy, as well as the pressing need for direct and indirect exploitation of solar energy, pose challenges to the science and technology community of today. Bioenergy, bulk chemicals, and biomaterials could be produced from renewable biomass in a biorefinery via biocatalysis. These sustainable industries will match the global mass cycle, creating a new form of civilization with new industries and agriculture driven by solar energy. Industrial biotechnology is the dynamo of a bioeconomy, leading to a new protocol for production of energy, bulk chemicals, and materials. This new mode of innovation will place the industry at center stage supported by universities and research institutes. Creativity in industrial biotechnology will be promoted and China will successfully follow the road to green modernization. China's rapid economic development and its traditional capacity in fermentation will place it in an advantageous position in the industrial biotechnology revolution. The development and current status of industrial biotechnology in China are summarized herein.

  20. Modernizing the Regulatory System for Biotechnology Products

    Science.gov (United States)

    This Web page describes the continuing effort to modernize the federal regulatory system for biotechnology products as well as clarify various roles of EPA, FDA and USDA in evaluating new biotechnology products.

  1. Applied thermodynamics: A new frontier for biotechnology

    DEFF Research Database (Denmark)

    Mollerup, Jørgen

    2006-01-01

    The scientific career of one of the most outstanding scientists in molecular thermodynamics, Professor John M. Prausnitz at Berkeley, reflects the change in the agenda of molecular thermodynamics, from hydrocarbon chemistry to biotechnology. To make thermodynamics a frontier for biotechnology...

  2. Biotechnology Facility (BTF) for ISS

    Science.gov (United States)

    1998-01-01

    Engineering mockup shows the general arrangement of the plarned Biotechnology Facility inside an EXPRESS rack aboard the International Space Station. This layout includes a gas supply module (bottom left), control computer and laptop interface (bottom right), two rotating wall vessels (top right), and support systems.

  3. BIOTECHNOLOGY OF THE FISH AQUACULTURE

    Directory of Open Access Journals (Sweden)

    L. P. Buchatsky

    2013-12-01

    Full Text Available The latest progress in biotechnology on fish aquaculture and different modern methods of investigations for increasing of fish productivity in aquaculture are analyzed. Except for the applied aspect, the use of modern biotechnological methods of investigations opens new possibilities for fundamental researches of sex-determining mechanisms, polyploidy, distant hybridization, and developmental biology of bony fishes. Review contains examples of utilizing modern biotechnology methods to obtain transgenic fishes with accelerated growth and for designing surrogate fishes. Methods for receiving unisexual shoals of salmon and sturgeon female fishes with the view of obtaining a large quantity of caviar, as well as receiving sterile (triploid fishes are analyzed. Great attention is given to androgenesis, particularly to disperm one, in connection with the problem of conserving rare and vanishing fish species using only sperm genetic material. Examples how distant hybrids may be obtained with the use of disperm androgenesis and alkylated DNA are given. Methods of obtaining fish primordium germ cells, recent developments in cultivation of fish stem cells and their use in biotechnology, as well as ones of transplantation of oogonium and spermatogonium to obtain surrogate fishes. The examples of successful experiments on spermatogonial xenotransplantation and characteristic of antifreezing fish proteins and also the prospect of their practical usage are given.

  4. Infusing Authentic Inquiry into Biotechnology

    Science.gov (United States)

    Hanegan, Nikki L.; Bigler, Amber

    2009-01-01

    Societal benefit depends on the general public's understandings of biotechnology (Betsch in "World J Microbiol Biotechnol" 12:439-443, 1996; Dawson and Cowan in "Int J Sci Educ" 25(1):57-69, 2003; Schiller in "Business Review: Federal Reserve Bank of Philadelphia" (Fourth Quarter), 2002; Smith and Emmeluth in "Am Biol Teach" 64(2):93-99, 2002). A…

  5. Biotechnology in defence (Review Paper

    Directory of Open Access Journals (Sweden)

    T. Lazar Mathew

    2001-10-01

    Full Text Available Biotechnology, in its present perspective, encompasses activities, such as recombination of genes; cloning, or making genetically identical copies of a living thing; and splicing of genes from DNA of one organism into the genome of unrelated species, to create new, self-reproducing forms of life. The vast potential of biotechnology is being increasingly realised, and efforts are in progress to harness it for improving quality and quantity of bio-weapons, The bio-weapons, as such, are highly attractive because of their non-detection by routine security systems, ease of access, low production cost and easy transportation, A wide range of genetically manipulated organisms and their by-products are considered to have an added advantage, because these genetically manipulated biologics not only accentuate the existing properties of bio-weapons, but also could be made target-specific. Biotechnology, if used prudently, can play a significant role to counter such threats of biologics, viz., by producing (i bio-armoury comprising powerful antibiotics, antisera toxoids and vaccines to neutralise and eliminate a wide range of diseases, and (ii bio-sensors for rapid detection, identification and neutralisation of biological warfare agents. This article elucidates some facets of biological warfare, legal protective strategies emphasised through international consultation, cooperation and adherence to the Biological and Toxin Weapons Convention, and discusses how biotechnology could be effectively used to strengthen countries' defence and combat the threat of biological warfare.

  6. Turkish university students' knowledge of biotechnology and attitudes toward biotechnological applications.

    Science.gov (United States)

    Öztürk-Akar, Ebru

    2016-09-10

    This study questions the presumed relation between formal schooling and scientific literacy about biotechnologies. Comparing science and nonscience majors' knowledge of and attitudes toward biotechnological applications, conclusions are drawn if their formal learnings improve pupils' understandings of and attitudes toward biotechnology applications. Sample of the study consists of 403 undergraduate and graduate students, 198 nonscience, and 205 science majors. The Biotechnology Knowledge Questionnaire and the Biotechnology Attitude Questionnaire were administered. Descriptive statistics (mean and percentages), t test, and correlations were used to examine the participants' knowledge of biotechnology and attitudes toward biotechnological applications and differences as regards their majors. Although the science majors had higher knowledge and attitude scores than the nonscience majors, it is not possible to say that they have sufficient knowledge of biotechnologies. Besides, the participants' attitudes toward biotechnological applications were not considerably related to their knowledge of biotechnology. © 2016 by The International Union of Biochemistry and Molecular Biology, 2016.

  7. Workshop proceedings: challenges and opportunities in evaluating protein allergenicity across biotechnology industries.

    Science.gov (United States)

    Stagg, Nicola J; Ghantous, Hanan N; Ladics, Gregory S; House, Robert V; Gendel, Steven M; Hastings, Kenneth L

    2013-01-01

    A workshop entitled "Challenges and Opportunities in Evaluating Protein Allergenicity across Biotechnology Industries" was held at the 51st Annual Meeting of the Society of Toxicology (SOT) in San Francisco, California. The workshop was sponsored by the Biotechnology Specialty Section of SOT and was designed to present the science-based approaches used in biotechnology industries to evaluate and regulate protein allergenicity. A panel of experts from industry and government highlighted the allergenicity testing requirements and research in the agricultural, pharmaceutical/biopharma, and vaccine biotechnology industries and addressed challenges and opportunities for advancing the science of protein allergenicity. The main learning from the workshop was that immunoglobulin E-mediated allergenicity of biotechnology-derived products is difficult to assess without human data. The approaches currently being used to evaluate potential for allergenicity across biotechnology industries are very different and range from bioinformatics, in vitro serology, in vivo animal testing, in vitro and in vivo functional assays, and "biosimilar" assessments (ie, biotherapeutic equivalents to innovator products). The challenge remains with regard to the different or lack of regulatory requirements for allergenicity testing across industries, but the novel approaches being used with bioinformatics and biosimilars may lead to opportunities in the future to collaborate across biotechnology industries.

  8. Recent patents in plant biotechnology: impact on global health.

    Science.gov (United States)

    Hefferon, Kathleen L

    2012-08-01

    Agricultural biotechnology offers a robust series of tools by which to address global concerns such as food security, crop protection, and fuel/energy requirements. A number of advances made recently in plant molecular biology also have resulted in applications which largely focus on improving global human health. This review describes some of the recent innovations in plant biotechnology that have come to the forefront over the past year. Included are novel techniques by which plants can be improved as platforms for biopharmaceutical protein production, a growing field also referred to as 'molecular pharming'. The metabolic engineering of plants to produce compounds which have additional nutritional benefits is also outlined. The review concludes with a discussion of the future impact that these innovations may have both on global health and on the development of our future intellectual property landscape.

  9. Excitement of biotechnology in the new economy (Review Paper

    Directory of Open Access Journals (Sweden)

    Kiran Mazumdar-Shaw

    2001-10-01

    Full Text Available "Today the world economy is no longer driven by material wealth but instead powered by intellectual wealth. Knowledge in the economic context translates to technology, of which information technology and biotechnology are the prime drivers, India has made it in information technology. but not yet in biotechnology. The exciting synergy between information technology and biotechnology in the form of bioinformatics is paving the way for intellectual wealth creation in the areas of health care (including pharmaceuticals, food and agriculture. The race for discovering new lead molecules is frenzied in the pharmaceutical arena, being mined by high throughput screening techniques for new chemical entities. The Himalayan yew tree. for example, has provided a billion dollar cancer drug. taxol. Pharmacogenomics is providing ' a wealth of information pertaining to defective or missing genes-a new avenue for drug research. A new trend in bioinformatics is in silica testing, which involves computational simulation of in vivo and in vitro tests, providing better predictability of clinical trials. In gene therapy cloning and expressing healthy genes is simple, but finding a mechanism to deliver these genes into target cells is the difficult part. Promising methods include virus as well as non-virus-based delivery systems. How Indians can take advantage of the exciting opportunities in biotechnology? One can boast of a treasure chest of biodiversities-microbial, plant, animal and human, but it is largely unutilised. A large number of inbred communities in India are offering unique human genome pools for genomic studies. We have the main ingredient for global success in biotechnology-our scientific manpower. We need to harness this talent in an enabling business environment and a pragmatic, entrepreneurial mindset. "

  10. The rise (and decline?) of biotechnology.

    Science.gov (United States)

    Kinch, Michael S

    2014-11-01

    Since the 1970s, biotechnology has been a key innovator in drug development. An analysis of FDA-approved therapeutics demonstrates pharmaceutical companies outpace biotechs in terms of new approvals but biotechnology companies are now responsible for earlier-stage activities (patents, INDs or clinical development). The number of biotechnology organizations that contributed to an FDA approval began declining in the 2000s and is at a level not seen since the 1980s. Whereas early biotechnology companies had a decade from first approval until acquisition, the average acquisition of a biotechnology company now occurs months before their first FDA approval. The number of hybrid organizations that arise when pharmaceutical companies acquire biotechnology is likewise declining, raising questions about the sustainability of biotechnology.

  11. Journal of Northeast Agricultural University (English Edition)%Journal of Northeast Agricultural University (English Edition)

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Instruction to Authors Aims and Scope Journal of Northeast Agricultural University (English Edition) is a comprehensive academic journal on agricultural sciences sponsored by Northeast Agricultural University and distributed worldwide. It is a peer reviewed journal published quarterly and mainly publishes review and research articles that reflect the latest achievements on crop science, horticulture, plant protection, resource and environment, animal science, veterinary medicine, agricultural engineering and technology, agricultural water conservancy, life science, biotechnology and food science.

  12. Biotechnology Science Experiments on Mir

    Science.gov (United States)

    Kroes, Roger L.

    1999-01-01

    This paper describes the microgravity biotechnology experiments carried out on the Shuttle/Mir program. Four experiments investigated the growth of protein crystals, and three investigated cellular growth. Many hundreds of protein samples were processed using four different techniques. The objective of these experiments was to determine optimum conditions for the growth of very high quality single crystals to be used for structure determination. The Biotechnology System (BTS) was used to process the three cell growth investigations. The samples processed by these experiments were: bovine chondrocytes, human renal epithelial cells, and human breast cancer cells and endothelial cells. The objective was to determine the unique properties of cell aggregates produced in the microgravity environment.

  13. New challenges in microalgae biotechnology.

    Science.gov (United States)

    Valverde, Federico; Romero-Campero, Francisco J; León, Rosa; Guerrero, Miguel G; Serrano, Aurelio

    2016-08-01

    Photosynthetic protists, also called microalgae, have been systematically studied for more than a century. However, only recently broad biotechnological applications have fostered a novel wave of research on their potentialities as sustainable resources of renewable energy as well as valuable industrial and agro-food products. At the recent VII European Congress of Protistology held in Seville, three outstanding examples of different research strategies on microalgae with biotechnological implications were presented, which suggested that integrative approaches will produce very significant advances in this field in the next future. In any case, intense research and the application of systems biology and genetic engineering techniques are absolutely essential to reach the full potential of microalgae as cell-factories of bio-based products and, therefore, could contribute significantly to solve the problems of biosustainability and energy shortage.

  14. Biodiesel production by microalgal biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Huang, GuanHua [School of Chemical Engineering and Technology, China University of Mining and Technology (China); Chen, Feng [School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong (China); College of Light Industry and Food Sciences, South China University of Technology, Guangzhou (China); Wei, Dong; Zhang, XueWu; Chen, Gu [College of Light Industry and Food Sciences, South China University of Technology, Guangzhou (China)

    2010-01-15

    Biodiesel has received much attention in recent years. Although numerous reports are available on the production of biodiesel from vegetable oils of terraneous oil-plants, such as soybean, sunflower and palm oils, the production of biodiesel from microalgae is a newly emerging field. Microalgal biotechnology appears to possess high potential for biodiesel production because a significant increase in lipid content of microalgae is now possible through heterotrophic cultivation and genetic engineering approaches. This paper provides an overview of the technologies in the production of biodiesel from microalgae, including the various modes of cultivation for the production of oil-rich microalgal biomass, as well as the subsequent downstream processing for biodiesel production. The advances and prospects of using microalgal biotechnology for biodiesel production are discussed. (author)

  15. Drugs obtained by biotechnology processing

    OpenAIRE

    Hugo de Almeida; Maria Helena Amaral; Paulo Lobão

    2011-01-01

    In recent years, the number of drugs of biotechnological origin available for many different diseases has increased exponentially, including different types of cancer, diabetes mellitus, infectious diseases (e.g. AIDS Virus / HIV) as well as cardiovascular, neurological, respiratory, and autoimmune diseases, among others. The pharmaceutical industry has used different technologies to obtain new and promising active ingredients, as exemplified by the fermentation technique, recombinant DNA tec...

  16. Biotechnology, Industry Study, Spring 2009

    Science.gov (United States)

    2009-01-01

    to meet future demands. However, improving crop production through the use of genetics offers a sustainable alternative. Companies such as Monsanto ...Nations Population Division, World Population Prospects, September 20, 2007, http://esa.un.org/unpp/. 25 Monsanto Company, “ Monsanto ~ Our Products...papers.cfm?abstract_id=1321054 28 Monsanto Company, "Conversations About Plant Biotechnology," April 25, 2009, http://www.monsanto.com/biotech-gmo/asp

  17. Applications of cyanobacteria in biotechnology.

    Science.gov (United States)

    Abed, R M M; Dobretsov, S; Sudesh, K

    2009-01-01

    Cyanobacteria have gained a lot of attention in recent years because of their potential applications in biotechnology. We present an overview of the literature describing the uses of cyanobacteria in industry and services sectors and provide an outlook on the challenges and future prospects of the field of cyanobacterial biotechnology. Cyanobacteria have been identified as a rich source of biologically active compounds with antiviral, antibacterial, antifungal and anticancer activities. Several strains of cyanobacteria were found to accumulate polyhydroxyalkanoates, which can be used as a substitute for nonbiodegradable petrochemical-based plastics. Recent studies showed that oil-polluted sites are rich in cyanobacterial consortia capable of degrading oil components. Cyanobacteria within these consortia facilitated the degradation processes by providing the associated oil-degrading bacteria with the necessary oxygen, organics and fixed nitrogen. Cyanobacterial hydrogen has been considered as a very promising source of alternative energy, and has now been made commercially available. In addition to these applications, cyanobacteria are also used in aquaculture, wastewater treatment, food, fertilizers, production of secondary metabolites including exopolysaccharides, vitamins, toxins, enzymes and pharmaceuticals. Future research should focus on isolating new cyanobacterial strains producing high value products and genetically modifying existing strains to ensure maximum production of the desired products. Metagenomic libraries should be constructed to discover new functional genes that are involved in the biosynthesis of biotechnological relevant compounds. Large-scale industrial production of the cyanobacterial products requires optimization of incubation conditions and fermenter designs in order to increase productivity.

  18. Impact of biotechnology on sugarcane agriculture and industry

    Science.gov (United States)

    There are nine key issues that can influence the productivity and sustainability of the sugarcane industry. These include land, soil fertility, water, variety, planting density, crop protection, cultural practices, harvesting and processing, and information technology. To all sugarcane farmers, it r...

  19. Impacts of Agricultural Biotechnology on China's Economy and World Trade

    NARCIS (Netherlands)

    Huang, Jikun; Ruifa, Hu; Meijl, van H.; Tongeren, van F.W.

    2002-01-01

    This paper analyses the impact of adopting non-food genetically modified organisms (GMOs) in China on production, trade and welfare. On the one hand the paper focuses on the productivity enhancing impact of GMOs and on the other hand it treats the consequences of some form of restrictions on Chinese

  20. Agricultural biotechnology. Monsanto donates its share of golden rice.

    Science.gov (United States)

    Normile, D

    2000-08-11

    Monsanto Co. has agreed to provide royalty-free licenses to speed up work on a genetically modified rice that could alleviate vitamin A deficiency around the world. Researchers welcomed last week's announcement, but warn that a thicket of intellectual property claims surrounds the technology and that significant legal hurdles remain before the rice can become widely available to farmers in developing countries.

  1. The Neoliberal University and Agricultural Biotechnology: Reports from the Field

    Science.gov (United States)

    Peekhaus, Wilhelm

    2010-01-01

    Following in the footsteps of a variety of previous research that elaborates on the current state of affairs in academia, this article sets out the argument that neoliberalism and its corresponding iterations of science and technology and research funding policies in this country have implications for the types of knowledge that can be generated…

  2. Public Acceptance of Plant Biotechnology and GM Crops

    Directory of Open Access Journals (Sweden)

    Jan M. Lucht

    2015-07-01

    Full Text Available A wide gap exists between the rapid acceptance of genetically modified (GM crops for cultivation by farmers in many countries and in the global markets for food and feed, and the often-limited acceptance by consumers. This review contrasts the advances of practical applications of agricultural biotechnology with the divergent paths—also affecting the development of virus resistant transgenic crops—of political and regulatory frameworks for GM crops and food in different parts of the world. These have also shaped the different opinions of consumers. Important factors influencing consumer’s attitudes are the perception of risks and benefits, knowledge and trust, and personal values. Recent political and societal developments show a hardening of the negative environment for agricultural biotechnology in Europe, a growing discussion—including calls for labeling of GM food—in the USA, and a careful development in China towards a possible authorization of GM rice that takes the societal discussions into account. New breeding techniques address some consumers’ concerns with transgenic crops, but it is not clear yet how consumers’ attitudes towards them will develop. Discussions about agriculture would be more productive, if they would focus less on technologies, but on common aims and underlying values.

  3. Public Acceptance of Plant Biotechnology and GM Crops.

    Science.gov (United States)

    Lucht, Jan M

    2015-07-30

    A wide gap exists between the rapid acceptance of genetically modified (GM) crops for cultivation by farmers in many countries and in the global markets for food and feed, and the often-limited acceptance by consumers. This review contrasts the advances of practical applications of agricultural biotechnology with the divergent paths-also affecting the development of virus resistant transgenic crops-of political and regulatory frameworks for GM crops and food in different parts of the world. These have also shaped the different opinions of consumers. Important factors influencing consumer's attitudes are the perception of risks and benefits, knowledge and trust, and personal values. Recent political and societal developments show a hardening of the negative environment for agricultural biotechnology in Europe, a growing discussion-including calls for labeling of GM food-in the USA, and a careful development in China towards a possible authorization of GM rice that takes the societal discussions into account. New breeding techniques address some consumers' concerns with transgenic crops, but it is not clear yet how consumers' attitudes towards them will develop. Discussions about agriculture would be more productive, if they would focus less on technologies, but on common aims and underlying values.

  4. Enrichment and Strengthening of Indian Biotechnology Industry along with Academic Interface

    Science.gov (United States)

    Singh, Shalini

    2014-01-01

    For many years, humankind has been incorporating biosciences in different places--from agriculture to food and medicine. Today, the nomenclature of biology has been recoined as Biotechnology, a technological science with a perfect blend of sophisticated techniques, manuals and application of fast delivery equipment and vehicles. It encompasses…

  5. Against Free Markets, against Science? Regulating the Socio-Economic Effects of Biotechnology

    Science.gov (United States)

    Kinchy, Abby J.; Kleinman, Daniel Lee; Autry, Robyn

    2008-01-01

    This study challenges the assumption that abstract "globalization" forces are driving transformations in the relationships between states and markets. Employing three cases of policy debate regarding the regulation of agricultural biotechnology (ag-biotech), we examine the role of discourse in the formation of neoliberal regulatory schemes. We…

  6. Editorial: Latest methods and advances in biotechnology.

    Science.gov (United States)

    Lee, Sang Yup; Jungbauer, Alois

    2014-01-01

    The latest "Biotech Methods and Advances" special issue of Biotechnology Journal continues the BTJ tradition of featuring the latest breakthroughs in biotechnology. The special issue is edited by our Editors-in-Chief, Prof. Sang Yup Lee and Prof. Alois Jungbauer and covers a wide array of topics in biotechnology, including the perennial favorite workhorses of the biotech industry, Chinese hamster ovary (CHO) cell and Escherichia coli.

  7. Medical Biotechnology: Problems and Prospects in Bangladesh

    OpenAIRE

    Shaikh Mizan

    2013-01-01

    Biotechnology is the knowledge and techniques of developing and using biological systems for deriving special products and services. The age-old technology took a new turn with the advent of recombinant DNA techniques, and boosted by the development of other molecular biological techniques, cell culture techniques and bioinformatics. Medical biotechnology is the major thrust area of biotechnology. It has brought revolutions in medicine – quick methods for diagnosing diseases, generation of ne...

  8. Biotechnological and industrial significance of cyanobacterial secondary metabolites.

    Science.gov (United States)

    Rastogi, Rajesh P; Sinha, Rajeshwar P

    2009-01-01

    Cyanobacteria are considered to be a rich source of novel metabolites of a great importance from a biotechnological and industrial point of view. Some cyanobacterial secondary metabolites (CSMs), exhibit toxic effects on living organisms. A diverse range of these cyanotoxins may have ecological roles as allelochemicals, and could be employed for the commercial development of compounds with applications such as algaecides, herbicides and insecticides. Recently, cyanobacteria have become an attractive source of innovative classes of pharmacologically active compounds showing interesting and exciting biological activities ranging from antibiotics, immunosuppressant, and anticancer, antiviral, antiinflammatory to proteinase-inhibiting agents. A different but not less interesting property of these microorganisms is their capacity of overcoming the toxicity of ultraviolet radiation (UVR) by means of UV-absorbing/screening compounds, such as mycosporine-like amino acids (MAAs) and scytonemin. These last two compounds are true 'multipurpose' secondary metabolites and considered to be natural photoprotectants. In this sense, they may be biotechnologically exploited by the cosmetic industry. Overall CSMs are striking targets in biotechnology and biomedical research, because of their potential applications in agriculture, industry, and especially in pharmaceuticals.

  9. Improving microalgae for biotechnology--From genetics to synthetic biology.

    Science.gov (United States)

    Hlavova, Monika; Turoczy, Zoltan; Bisova, Katerina

    2015-11-01

    Microalgae have traditionally been used in many biotechnological applications, where each new application required a different species or strain expressing the required properties; the challenge therefore is to isolate or develop, characterize and optimize species or strains that can express more than one specific property. In agriculture, breeding of natural variants has been successfully used for centuries to improve production traits in many existing plant and animal species. With the discovery of the concepts of classical genetics, these new ideas have been extensively used in selective breeding. However, many biotechnologically relevant algae do not possess the sexual characteristics required for traditional breeding/crossing, although they can be modified by chemical and physical mutagens. The resulting mutants are not considered as genetically modified organisms (GMOs) and their cultivation is therefore not limited by legislation. On the other hand, mutants prepared by random or specific insertion of foreign DNA are considered to be GMOs. This review will compare the effects of two genetic approaches on model algal species and will summarize their advantages in basic research. Furthermore, we will discuss the potential of mutagenesis to improve microalgae as a biotechnological resource, to accelerate the process from specific strain isolation to growth optimization, and discuss the production of new products. Finally, we will explore the potential of algae in synthetic biology.

  10. Biotechnological Production of Organic Acids from Renewable Resources.

    Science.gov (United States)

    Pleissner, Daniel; Dietz, Donna; van Duuren, Jozef Bernhard Johann Henri; Wittmann, Christoph; Yang, Xiaofeng; Lin, Carol Sze Ki; Venus, Joachim

    2017-03-07

    Biotechnological processes are promising alternatives to petrochemical routes for overcoming the challenges of resource depletion in the future in a sustainable way. The strategies of white biotechnology allow the utilization of inexpensive and renewable resources for the production of a broad range of bio-based compounds. Renewable resources, such as agricultural residues or residues from food production, are produced in large amounts have been shown to be promising carbon and/or nitrogen sources. This chapter focuses on the biotechnological production of lactic acid, acrylic acid, succinic acid, muconic acid, and lactobionic acid from renewable residues, these products being used as monomers for bio-based material and/or as food supplements. These five acids have high economic values and the potential to overcome the "valley of death" between laboratory/pilot scale and commercial/industrial scale. This chapter also provides an overview of the production strategies, including microbial strain development, used to convert renewable resources into value-added products.

  11. Peculiarities of Pycnoporus species for applications in biotechnology.

    Science.gov (United States)

    Lomascolo, Anne; Uzan-Boukhris, Eva; Herpoël-Gimbert, Isabelle; Sigoillot, Jean-Claude; Lesage-Meessen, Laurence

    2011-12-01

    The genus Pycnoporus forms a cosmopolitan group of four species belonging to the polyporoid white-rot fungi, the most representative group of homobasidiomycetes causing wood decay. Pycnoporus fungi are listed as food- and cosmetic-grade microorganisms and emerged in the early 1990s as a genus whose biochemistry, biodegradation and biotechnological properties have since been progressively detailed. First highlighted for their original metabolic pathways involved in the functionalization of plant cell wall aromatic compounds to yield high-value molecules, e.g. aromas and antioxidants, the Pycnoporus species were later explored for their potential to produce various enzymes of industrial interest, such as hydrolases and oxidases. However, the most noteworthy feature of the genus Pycnoporus is its ability to overproduce high redox potential laccase-a multi-copper extracellular phenoloxidase-as the predominant ligninolytic enzyme. A major potential use of the Pycnoporus fungi is thus to harness their laccases for various applications such as the bioconversion of agricultural by-products and raw plant materials into valuable products, the biopulping and biobleaching of paper pulp and the biodegradation of organopollutants, xenobiotics and industrial contaminants. All the studies performed in the last decade show the genus Pycnoporus to be a strong contender for white biotechnology. In this review, we describe the properties of Pycnoporus fungi in relation to their biotechnological applications and potential.

  12. Fungal genome sequencing: basic biology to biotechnology.

    Science.gov (United States)

    Sharma, Krishna Kant

    2016-08-01

    The genome sequences provide a first glimpse into the genomic basis of the biological diversity of filamentous fungi and yeast. The genome sequence of the budding yeast, Saccharomyces cerevisiae, with a small genome size, unicellular growth, and rich history of genetic and molecular analyses was a milestone of early genomics in the 1990s. The subsequent completion of fission yeast, Schizosaccharomyces pombe and genetic model, Neurospora crassa initiated a revolution in the genomics of the fungal kingdom. In due course of time, a substantial number of fungal genomes have been sequenced and publicly released, representing the widest sampling of genomes from any eukaryotic kingdom. An ambitious genome-sequencing program provides a wealth of data on metabolic diversity within the fungal kingdom, thereby enhancing research into medical science, agriculture science, ecology, bioremediation, bioenergy, and the biotechnology industry. Fungal genomics have higher potential to positively affect human health, environmental health, and the planet's stored energy. With a significant increase in sequenced fungal genomes, the known diversity of genes encoding organic acids, antibiotics, enzymes, and their pathways has increased exponentially. Currently, over a hundred fungal genome sequences are publicly available; however, no inclusive review has been published. This review is an initiative to address the significance of the fungal genome-sequencing program and provides the road map for basic and applied research.

  13. Current status of biotechnology in Slovakia.

    Science.gov (United States)

    Stuchlík, Stanislav; Turna, Ján

    2013-07-01

    The United Nations Convention on Biological Diversity defines biotechnology as: 'Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use.' In other words biotechnology is 'application of scientific and technical advances in life science to develop commercial products' or briefly 'the use of molecular biology for useful purposes'. This short overview is about different branches of biotechnology carried out in Slovakia and it shows that Slovakia has a good potential for further development of modern biotechnologies.

  14. Undergraduate Biotechnology Students' Views of Science Communication

    Science.gov (United States)

    Edmondston, Joanne Elisabeth; Dawson, Vaille; Schibeci, Renato

    2010-12-01

    Despite rapid growth of the biotechnology industry worldwide, a number of public concerns about the application of biotechnology and its regulation remain. In response to these concerns, greater emphasis has been placed on promoting biotechnologists' public engagement. As tertiary science degree programmes form the foundation of the biotechnology sector by providing a pipeline of university graduates entering into the profession, it has been proposed that formal science communication training be introduced at this early stage of career development. The aim of the present study was to examine the views of biotechnology students towards science communication and science communication training. Using an Australian biotechnology degree programme as a case study, 69 undergraduates from all three years of the programme were administered a questionnaire that asked them to rank the importance of 12 components of a biotechnology curriculum, including two science communication items. The results were compared to the responses of 274 students enrolled in other science programmes. Additional questions were provided to the second year biotechnology undergraduates and semi-structured interviews were undertaken with 13 of these students to further examine their views of this area. The results of this study suggest that the biotechnology students surveyed do not value communication with non-scientists nor science communication training. The implications of these findings for the reform of undergraduate biotechnology courses yet to integrate science communication training into their science curriculum are discussed.

  15. Biotechnology: employing organism as bioreactors

    Directory of Open Access Journals (Sweden)

    Maryam Baniasad

    2015-06-01

    Full Text Available Biological products, especially proteins, have numerous applications including prevention, diagnosis, and treating diseases. Advances in biotechnology in recent years have opened up many ways to manufacture these products in large scales. To engineer biopharmaceuticals, often pro and/or eukaryotic sustainable resources are used. Selection of the cellular factory depends on the type and application of protein needed. In this review, we explore current resources used to produce biologics, examine these resources critically for their biological output, and finally highlight impact of using sustainable resources in modern medicine.

  16. Biotechnology

    Science.gov (United States)

    2005-01-01

    impact of the bioattack. The combined initiatives of BioWatch,113 and BioSurveillance ,114 among others, provide fundamental building blocks for ensuring...nationwide grid of air sampling devices and routine analysis. 114 The CDC has also submitted an FY2005 initiative called BioSurveillance that...terrorism,” 2 March 2005, <http://www.fbis.gov/ portal /server.pt/gateway/PTARGS_0_1518_215_240_0_43/> (accessed 23 March 2005). “New MS drug

  17. Biotechnology

    Science.gov (United States)

    2001-01-01

    scientific world successfully cloned plants and animals, discovered and created new pharmaceuticals and mapped the human genome. However, where does...ethical concerns currently being debated are the FDA’s requirements for testing new pharmaceuticals before being approved for use. Generally, the

  18. Chronological development avenues in biotechnology across the world

    Directory of Open Access Journals (Sweden)

    Prashant Y Mali

    2011-01-01

    Full Text Available Biotechnology is expected to be a great technological revolution followed by information technology. It is an application of scientific and engineering principles to the processing of material by biological agents to provide better goods and services to mankind. Commercially its techniques are applied long back in 6 th century in the art of brewing, wine making and baking. It has progressed there after crossing different land marks. Modern biotechnology has developed significantly in the late 19 th century with groundbreaking discoveries applicable in medicine, food, agriculture, chemistry, environmental protection and many more industries. It is widely used in the development of high-yielding, disease-resistant, better quality varieties by applying tissue culture and recombinant DNA techniques. It has wide application in animal breeding using techniques such as artificial insemination, in vitro fertilization and embryo transfer. Specific enzymes used in laundry, fuel and leather industries for better quality, economically feasible and environmental friendly production. Biotechnology in healthcare system uses body′s own tools and weapons to fight against diseases, manufacturing of targeted therapeutic proteins, gene therapy and so on. Novel approaches such as proteomics and structural biology are contributing to understanding the chemistry of life and diseases. Malfunctioning gene replaced with correctly functioning gene by using gene therapy. Tissue engineering has opened up the use of in vitro developed tissue or organ in repairing wounded tissue and system biology which is a computer-based approach to understand cell functions. Although every new discovery related to biology and its implications is significant and has taken the technology ahead. This includes applications, commercialization, controversies, media exposure and so on. Hence, we have enlisted some of the chronological development avenues in biotechnology across the world.

  19. Biotechnology in the Middle School Curriculum

    Science.gov (United States)

    Campbell, De Ann

    2007-01-01

    Biotechnology is a fairly new concept for middle school students as well as teachers. If the latest craze of TV shows focused on crime scene investigation events were not so popular, the term and concept might be even obscure to the public. There is an increased presence of biotechnology in our daily surroundings that makes it practical and…

  20. Assessment and diffusion of biotechnology drugs

    NARCIS (Netherlands)

    Zwart-van Rijkom, J.E.F.

    2002-01-01

    Biotechnology, viewed as a young and innovative field, is associated with great possibilities and high expectation on patient benefits. But there are also public controversies on ethical, social and economic issues. Beginning with recombinant human insulin in 1982, more than 50 biotechnology drugs h

  1. Undergraduate Biotechnology Students' Views of Science Communication

    Science.gov (United States)

    Edmondston, Joanne Elisabeth; Dawson, Vaille; Schibeci, Renato

    2010-01-01

    Despite rapid growth of the biotechnology industry worldwide, a number of public concerns about the application of biotechnology and its regulation remain. In response to these concerns, greater emphasis has been placed on promoting biotechnologists' public engagement. As tertiary science degree programmes form the foundation of the biotechnology…

  2. Principles of biotechnological treatment of industrial wastes

    Energy Technology Data Exchange (ETDEWEB)

    Roig, M.G.; Martin Rodriguez, M.J.M.; Cachaza, J.M. (Univ. de Salamanca, Salamanca (Spain). Dept. de Quimica Fisica); Mendoza Sanchez, L. (C/Sol Oriente, Salamanca (Spain). Estudios y Proyectos); Kennedy, J.F. (Univ. of Birmingham, Birmingham (United Kingdom). Research Lab. for the Chemistry of Bioactive Carbohydrates and Proteins)

    1993-07-01

    This review includes current information on biodegradation processes of pollutants, digestor biocenosis and bioadditives, sludge production, measurement of pollution, and advances regarding biotechnological treatment of a series of specific industrial effluents. It was foreseen in 1980 that biotechnology would foster the creation of new industries with low energy requirements. This is because the growth of microorganisms provides a renewable source of energy.

  3. Biotechnology - The role of perceptions of consumers

    OpenAIRE

    P. Van Heerden; N. Lessing

    2002-01-01

    The development of Biotechnology is aimed at creating improved products. Without the acceptance of biotechnology enhancements by consumers, the development of new products will be hampered. Consumers in different countries perceive genetic engineering differently. In this article the views of foreign and local consumers are investigated.

  4. New trends in biotechnology. Biotechnology no atarashii choryu

    Energy Technology Data Exchange (ETDEWEB)

    Karube, I. (The University of Tokyo, Tokyo (Japan). Research Center for Advanced Science and Technology)

    1993-11-30

    This paper focuses on application of the recent biotechnology and introduces its new trends. What has triggered the boom in the application is when the technology has been applied to medicines in the 1970's. Beginning with insulin and interferon, various fibrinolytic agents including tPA and monoclonals have been put on markets one after another in 1991. Progress in humangenomic analysis has led to implementation of gene therapies and diagnoses using genes on gene diseases. Sweeteners used in a large quantity in the foodstuff field are fructoses made by isomerizing glucose produced by using enzymatic bioreactors. Needless to say about production of amino acid, organic acids, saccharides, antibiotics, steroids, and nucleic acid-based compounds by using enzymatic bioreactors, chemicals including acrylic amide from acrylonitrile, enzyme detergents, and bio-herbicides are available commercially. Progress in the technology is seen in all of the fields, including electronics industry and environmental preservation. 6 refs., 4 figs.

  5. Termites as targets and models for biotechnology.

    Science.gov (United States)

    Scharf, Michael E

    2015-01-07

    Termites have many unique evolutionary adaptations associated with their eusocial lifestyles. Recent omics research has created a wealth of new information in numerous areas of termite biology (e.g., caste polyphenism, lignocellulose digestion, and microbial symbiosis) with wide-ranging applications in diverse biotechnological niches. Termite biotechnology falls into two categories: (a) termite-targeted biotechnology for pest management purposes, and (b) termite-modeled biotechnology for use in various industrial applications. The first category includes several candidate termiticidal modes of action such as RNA interference, digestive inhibition, pathogen enhancement, antimicrobials, endocrine disruption, and primer pheromone mimicry. In the second category, termite digestomes are deep resources for host and symbiont lignocellulases and other enzymes with applications in a variety of biomass, industrial, and processing applications. Moving forward, one of the most important approaches for accelerating advances in both termite-targeted and termite-modeled biotechnology will be to consider host and symbiont together as a single functional unit.

  6. The current biotechnology outlook in Malaysia

    Directory of Open Access Journals (Sweden)

    Khairiah Salwa MOKHTAR

    2010-06-01

    Full Text Available Blessed with extremely rich biodiversity, Malaysia is all geared up to explore new high technology to utilize the advantage it possesses whilst to protect its environment. Biotechnology has been identified as an appropriate driver that can deliver economic gains through research and development, improvement of food security, creation of entrepreneurial opportunities for industrial growth, health and environmental sustainability. This paper attempts to address the evolution of biotechnology institutions and the stumbling blocks in developing the Malaysian biotechnology industry. This paper identifies three main impediments in the current Malaysian biotechnology, namely lack of skilled human capital; weak industrial base; and lack of commercialization effort. Besides, a set of strategies are discussed with aim to further improve and strengthen the Malaysian biotechnology industry. In general, the arguments are presented by mapping out the symbiotic relationship between data from elite interviews, archival data and observations.

  7. Western Australian school students' understanding of biotechnology

    Science.gov (United States)

    Dawson, Vaille; Schibeci, Renato

    2003-01-01

    Are science educators providing secondary school students with the background to understand the science behind recent controversies such as the recently introduced compulsory labelling of genetically modified foods? Research from the UK suggests that many secondary school students do not understand the processes or implications of modern biotechnology. The situation in Australia is unclear. In this study, 1116 15-year-old students from eleven Western Australian schools were surveyed to determine their understanding of, and attitude towards, recent advances in modern biotechnology. The results indicate that approximately one third of students have little or no understanding of biotechnology. Many students over-estimate the use of biotechnology in our society by confusing current uses with possible future applications. The results provide a rationale for the inclusion of biotechnology, a cutting edge science, in the school science curriculum

  8. A Review of EDVOTEK - The Biotechnology Education Company

    OpenAIRE

    Scott Stein

    2011-01-01

    Review of: EDVOTEK - The Biotechnology Education Company, a science equipment and supplies vendor specializing in biotechnology materials for middle school, high school and undergraduate college students.

  9. Biotechnology and bioforensics new trends

    CERN Document Server

    Kumar, Amit

    2015-01-01

    This Brief covers broad areas of Applied Biology specifically into the domains of Biotechnology/Biomedicine and Forensic Science. Chapters included here would also explain the role of bioinformatics in protein and gene characterization, modeling of the protein structure, survey related to the chromosomal effect on Human Disorders like Diabetes and Cardiac Problems. This Brief is full of Innovative Literature like Use of Microbes in Electricity Production, Brain connection to Type 2 Diabetes etc. Interesting issues in Forensic biology and the aspects of Bioforensics like STR profiling of exhumed bones makes this brief truly useful and informative for Researchers. It also includes the advancements and new ideologies in understanding crop improvements & crop quality. This Brief witnesses Innovative Research related to the Bio and Agri software development too which are capable of accelerating Insilico biological data analysis.

  10. Biotechnological production of citric acid

    Directory of Open Access Journals (Sweden)

    Belén Max

    2010-12-01

    Full Text Available This work provides a review about the biotechnological production of citric acid starting from the physicochemical properties and industrial applications, mainly in the food and pharmaceutical sectors. Several factors affecting citric acid fermentation are discussed, including carbon source, nitrogen and phosphate limitations, pH of culture medium, aeration, trace elements and morphology of the fungus. Special attention is paid to the fundamentals of biochemistry and accumulation of citric acid. Technologies employed at industrial scale such as surface or submerged cultures, mainly employing Aspergillus niger, and processes carried out with Yarrowia lipolytica, as well as the technology for recovering the product are also described. Finally, this review summarizes the use of orange peels and other by-products as feedstocks for the bioproduction of citric acid.

  11. Environmental biotechnology research: an overview.

    Science.gov (United States)

    Spain, J C

    1994-05-01

    Cleanup and treatment of hazardous wastes incur major operational costs for the U.S. Air Force. Bioremediation can provide a cost-effective alternative to traditional technologies for a wide range of natural organic compounds such as jet fuel. Bioventing and natural attenuation are emerging as treatments of choice in many instances. Synthetic organic chemicals are much more resistant to biodegradation. However, recent advances in biotechnology allow the development of strains able to use nitro- and chloro-substituted organic compounds as their sole source of carbon and energy. Current basic research is focused on expanding the range of synthetic chemicals amenable to biodegradation. At the same time, development of appropriate bioreactors and models for scale up are essential for practical application of the technology.

  12. Flashing light in microalgae biotechnology.

    Science.gov (United States)

    Abu-Ghosh, Said; Fixler, Dror; Dubinsky, Zvy; Iluz, David

    2016-03-01

    Flashing light can enhance photosynthesis and improve the quality and quantity of microalgal biomass, as it can increase the products of interest by magnitudes. Therefore, the integration of flashing light effect into microalgal cultivation systems should be considered. However, microalgae require a balanced mix of the light/dark cycle for higher growth rates, and respond to light intensity differently according to the pigments acquired or lost during the growth. This review highlights recently published results on flashing light effect on microalgae and its applications in biotechnology, as well as the recently developed bioreactors designed to fulfill this effect. It also discusses how this knowledge can be applied in selecting the optimal light frequencies and intensities with specific technical properties for increasing biomass production and/or the yield of the chemicals of interest by microalgae belonging to different genera.

  13. Drugs obtained by biotechnology processing

    Directory of Open Access Journals (Sweden)

    Hugo Almeida

    2011-06-01

    Full Text Available In recent years, the number of drugs of biotechnological origin available for many different diseases has increased exponentially, including different types of cancer, diabetes mellitus, infectious diseases (e.g. AIDS Virus / HIV as well as cardiovascular, neurological, respiratory, and autoimmune diseases, among others. The pharmaceutical industry has used different technologies to obtain new and promising active ingredients, as exemplified by the fermentation technique, recombinant DNA technique and the hybridoma technique. The expiry of the patents of the first drugs of biotechnological origin and the consequent emergence of biosimilar products, have posed various questions to health authorities worldwide regarding the definition, framework, and requirements for authorization to market such products.Nos últimos anos, tem aumentado exponencialmente o número de fármacos de origem biotecnológica ao dispor das mais diversas patologias, entre elas destacam-se, os diferentes tipos de cancêr, as doenças infecciosas (ex. vírus AIDS/HIV, as doenças autoimunes, as doenças cardiovasculares, a Diabetes Mellitus, as doenças neurológicas, as doenças respiratórias, entre outras. A indústria farmacêutica tem recorrido a diferentes tecnologias para a obtenção de novos e promissores princípios ativos, como são exemplo a fermentação, a técnica de DNA Recombinante, a técnica de hidridoma, entre outras. A queda das patentes dos primeiros fármacos de origem biotecnológica e o consequente aparecimento dos produtos biossimilares têm colocado diferentes questões às autoridades de saúde mundiais, sobre a definição, enquadramento e exigências para a autorização de entrada no mercado deste tipo de produtos.

  14. Journal of Northeast Agricultural University (English Edition)Instruction to Authors%Journal of Northeast Agricultural University (English Edition)Instruction to Authors

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Aims and Scope Journal of Northeast Agricultural University (English Edition) is a comprehensive academic journal on agricultural sciences sponsored by Northeast Agricultural University and distributed worldwide. It is a peer reviewed journal published quarterly and mainly publishes review and research articles that reflect the latest achievements on crop science, horticulture, plant protection, resource and environment, animal science, veterinary medicine, agricultural engineering and technology, agricultural water conservancy, life science, biotechnology and food science.

  15. European biotechnology: Business aspects. March 1985-November 1989 (Citations from the Biobusiness data base). Report for March 1985-November 1989

    Energy Technology Data Exchange (ETDEWEB)

    1989-12-01

    This bibliography contains citations concerning business issues of biotechnological research and development (R D) being conducted primarily in Western Europe. The major emphasis is on commercial agricultural and pharmaceutical R D companies. Business topics such as location, product technology, marketing strategies, sales statistics, competitive issues and market share, and consumption data are covered. Collaborative agreements between biotechnology firms located in Western Europe and leading biotechnology companies around the globe are also cited. This bibliography is germane to the upcoming consolidation of the European Econonic Community (EEC) and is of interest to biotechnology companies whose business/marketing plans include possible expansion into the EEC. (Contains 286 citations fully indexed and including a title list.)

  16. Frontiers in biomedical engineering and biotechnology.

    Science.gov (United States)

    Liu, Feng; Goodarzi, Ali; Wang, Haifeng; Stasiak, Joanna; Sun, Jianbo; Zhou, Yu

    2014-01-01

    The 2nd International Conference on Biomedical Engineering and Biotechnology (iCBEB 2013), held in Wuhan on 11–13 October 2013, is an annual conference that aims at providing an opportunity for international and national researchers and practitioners to present the most recent advances and future challenges in the fields of Biomedical Information, Biomedical Engineering and Biotechnology. The papers published by this issue are selected from this conference, which witnesses the frontier in the field of Biomedical Engineering and Biotechnology, which particularly has helped improving the level of clinical diagnosis in medical work.

  17. Surface biotechnology for refining cochlear implants.

    Science.gov (United States)

    Tan, Fei; Walshe, Peter; Viani, Laura; Al-Rubeai, Mohamed

    2013-12-01

    The advent of the cochlear implant is phenomenal because it is the first surgical prosthesis that is capable of restoring one of the senses. The subsequent rapid evolution of cochlear implants through increasing complexity and functionality has been synchronized with the recent advancements in biotechnology. Surface biotechnology has refined cochlear implants by directly influencing the implant–tissue interface. Emerging surface biotechnology strategies are exemplified by nanofibrous polymeric materials, topographical surface modification, conducting polymer coatings, and neurotrophin-eluting implants. Although these novel developments have received individual attention in the recent literature, the time has come to investigate their collective applications to cochlear implants to restore lost hearing.

  18. Biotechnology, nanotechnology, and pharmacogenomics and pharmaceutical compounding, Part 1.

    Science.gov (United States)

    Allen, Loyd V

    2015-01-01

    The world of pharmaceuticals is changing rapidly as biotechnology continues to grow and nanotechnology appears on the horizon. Biotechnology is gaining in importance in extemporaneous pharmaceutical compounding, and nanotechnology and pharmacogenomics could drastically change the practice of pharmacy. This article discusses biotechnology and the factors to consider when compounding biotechnology drugs.

  19. Agriculture in the xxi century: transgenic plants role in agricultural sector´s technological development

    Directory of Open Access Journals (Sweden)

    Rodrigo Artunduaga Salas

    2011-12-01

    Full Text Available The new advances in biotechnology, especially in the completion of the Arabidopsis thaliana, genome sequence has profound implications for human health as well as plant biology and agriculture. It will permit us to know the action of all the genes involved in the key growing and development processes of plants. Modification of the structure of genes will allow the regulation of the expression of some characteristics such as the size of the leaves or the dynamics of the roots and fruits growth. In this way, the commercialization of the products of the new biotechnologies will influence in this century´s nations, agricultural production, productivity and food supply. The challenges and opportunities for the countries of Latin America and the Caribbean (LAC are enormous, due to the rich base of their flora, fauna and microorganisms resources, which are essential to the pharmaceutical and feeding industries. The international Community recognizes the benefits of Biotechnology, but it also advocate more inquiry into the impacts of advanced agricultural biotechnologies on the environment, food system, structure of agriculture, rural communities, and population health.The countries of LAC should continue the development and improvement of the regulatory framework for preventing or minimizing the possible risks of the use and management of the transgenic organisms in their territory, and therefore, be able to make use of their potential benefits, ensuring the protection of public health and the environment.

  20. Principles of biotechnological treatment of industrial wastes.

    Science.gov (United States)

    Roig, M G; Martín Rodriguez, M J; Cachaza, J M; Mendoza Sánchez, L; Kennedy, J F

    1993-01-01

    This review includes current information on biodegradation processes of pollutants, digestor biocenosis and bioadditives, sludge production, measurement of pollution, and advances regarding biotechnological treatment of a series of specific industrial effluents.

  1. Application of biotechnology to improve livestock products

    Directory of Open Access Journals (Sweden)

    Swati Gupta

    Full Text Available Biotechnological achievements of recent years have emerged as powerful tool to improve quality attributes of livestock products including milk and meat products. Biotechnological approaches can be employed for improving productivity, economy, physicochemical and nutritional attributes of a wide range of livestock products. The target areas of biotechnological research in the field of livestock products can be envisaged as production of high yielding food animal, improvement in quality of their products, enhanced production of natural food grade preservatives, efficient byproduct utilization and so forth. Many of the biotechnological techniques can be explored in the area of quality assurance programmes, which would be of great help to produce livestock products of assured quality and public health safety. [Vet World 2012; 5(10.000: 634-638

  2. Biotechnology Education: A Multiple Instructional Strategies Approach.

    Science.gov (United States)

    Dunham, Trey; Wells, John; White, Karissa

    2002-01-01

    Provides a rationale for inclusion of biotechnology in technology education. Describes an instructional strategy that uses behaviorist, cognitive, and constructivist learning theories in two activities involving photobioreactors and bovine somatotropin (growth hormone). (Contains 39 references.) (SK)

  3. Mechatronics design principles for biotechnology product development.

    Science.gov (United States)

    Mandenius, Carl-Fredrik; Björkman, Mats

    2010-05-01

    Traditionally, biotechnology design has focused on the manufacture of chemicals and biologics. Still, a majority of biotechnology products that appear on the market today is the result of mechanical-electric (mechatronic) construction. For these, the biological components play decisive roles in the design solution; the biological entities are either integral parts of the design, or are transformed by the mechatronic system. This article explains how the development and production engineering design principles used for typical mechanical products can be adapted to the demands of biotechnology products, and how electronics, mechanics and biology can be integrated more successfully. We discuss three emerging areas of biotechnology in which mechatronic design principles can apply: stem cell manufacture, artificial organs, and bioreactors.

  4. The current biotechnology outlook in Malaysia

    OpenAIRE

    Khairiah Salwa MOKHTAR; Mahalingam, Ravi

    2010-01-01

    Blessed with extremely rich biodiversity, Malaysia is all geared up to explore new high technology to utilize the advantage it possesses whilst to protect its environment. Biotechnology has been identified as an appropriate driver that can deliver economic gains through research and development, improvement of food security, creation of entrepreneurial opportunities for industrial growth, health and environmental sustainability. This paper attempts to address the evolution of biotechnology in...

  5. Yeasts: from genetics to biotechnology.

    Science.gov (United States)

    Russo, S; Berkovitz Siman-Tov, R; Poli, G

    1995-01-01

    Yeasts have been known and used in food and alcoholic fermentations ever since the Neolithic Age. In more recent times, on the basis of their peculiar features and history, yeasts have become very important experimental models in both microbiological and genetic research, as well as the main characters in many fermentative production processes. In the last 40 years, advances in molecular biology and genetic engineering have made possible not only the genetic selection of organisms, but also the genetic modification of some of them, especially the simplest of them, such as bacteria and yeasts. These discoveries have led to the availability of new yeast strains fit to fulfill requests of industrial production and fermentation. Moreover, genetically modified and transformed yeasts have been constructed that are able to produce large amounts of biologically active proteins and enzymes. Thus, recombinant yeasts make it easier to produce drugs, biologically active products, diagnostics, and vaccines, by inexpensive and relatively simple techniques. Yeasts are going to become more and more important in the "biotechnological revolution" by virtue of both their features and their very long and safe use in human nutrition and industry.

  6. Ethics in biotechnology and biosecurity

    Directory of Open Access Journals (Sweden)

    S Jameel

    2011-01-01

    Full Text Available Great advances in technology produce unique challenges. Every technology also has a dual use, which needs to be understood and managed to extract maximum benefits for mankind and the development of civilization. The achievements of physicists in the mid-20th century resulted in the nuclear technology, which gave us the destructive power of the atomic bomb as also a source of energy. Towards the later part of the 20th century, information technology empowered us with fast, easy and cheap access to information, but also led to intrusions into our privacy. Today, biotechnology is yielding life- saving and life-enhancing advances at a fast pace. But, the same tools can also give rise to fiercely destructive forces. How do we construct a security regime for biology? What have we learnt from the management of earlier technological advances? How much information should be in the public domain? Should biology, or more broadly science, be regulated? Who should regulate it? These and many other ethical questions need to be addressed.

  7. Yeast Genetics and Biotechnological Applications

    Science.gov (United States)

    Mishra, Saroj; Baranwal, Richa

    Yeast can be recognized as one of the very important groups of microorganisms on account of its extensive use in the fermentation industry and as a basic eukaryotic model cellular system. The yeast Saccharomyces cerevisiae has been extensively used to elucidate the genetics and regulation of several key functions in the cell such as cell mating, electron transport chain, protein trafficking, cell cycle events and others. Even before the genome sequence of the yeast was out, the structural organization and function of several of its genes was known. With the availability of the origin of replication from the 2 μm plasmid and the development of transformation system, it became the host of choice for expression of a number of important proteins. A large number of episomal and integrative shuttle vectors are available for expression of mammalian proteins. The latest developments in genomics and micro-array technology have allowed investigations of individual gene function by site-specific deletion method. The application of metabolic profiling has also assisted in understanding the cellular network operating in this yeast. This chapter is aimed at reviewing the use of this system as an experimental tool for conducting classical genetics. Various vector systems available, foreign genes expressed and the limitations as a host will be discussed. Finally, the use of various yeast enzymes in biotechnology sector will be reviewed.

  8. Medical biotechnology trends and achievements in iran.

    Science.gov (United States)

    Mahboudi, Fereidoun; Hamedifar, Haleh; Aghajani, Hamideh

    2012-10-01

    A healthcare system has been the most important priority for all governments worldwide. Biotechnology products have affected the promotion of health care over the last thirty years. During the last several decades, Iran has achieved significant success in extending healthcare to the rural areas and in reducing the rates of infant mortality and increasing population growth. Biomedical technology as a converging technology is considered a helpful tool to fulfill the Iranian healthcare missions. The number of biotechnology products has reached 148 in 2012. The total sales have increased to 98 billion USD without considering vaccines and plasma derived proteins in 2012. Iran is one of the leading countries in the Middle East and North Africa in the area of Medical biotechnology. The number of biotechnology medicines launched in Iran is 13 products until 2012. More than 15 products are in pipelines now. Manufacturers are expecting to receive the market release for more than 8 products by the end of 2012. Considering this information, Iran will lead the biotechnology products especially in area of biosimilars in Asia after India in next three years. The present review will discuss leading policy, decision makers' role, human resource developing system and industry development in medical biotechnology.

  9. Journal of Northeast Agricultural University (English Edition) Instruction to Authors

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Aims and Scope Jo,rnal of Northeast Agricultural University (English Edition) is a comprehensive academic journal on agricultural sciences sponsored by Northeast Agricultural University and distributed worldwide. It is a peer reviewed journal published quarterly and mainly publishes review and research articles that reflect the latest achievements on crop science, horticulture, plant protection, resource and environment, animal science, veterinary medicine, agricultural engineering and technology, agricultural water conservancy. life science, biotechnology and food science.

  10. Attitudes in China about Crops and Foods Developed by Biotechnology.

    Science.gov (United States)

    Han, Fei; Zhou, Dingyang; Liu, Xiaoxia; Cheng, Jie; Zhang, Qingwen; Shelton, Anthony M

    2015-01-01

    Transgenic Bt cotton has been planted in China since 1997 and, in 2009, biosafety certificates for the commercial production of Bt rice and phytase corn were issued by the Chinese government. The public attitude in China toward agricultural biotechnology and genetically modified (GM) crops and foods has received considerable attention worldwide. We investigated the attitudes of consumers, Bt cotton farmers and scientists in China regarding GM crops and foods and the factors influencing their attitudes. Data were collected using interview surveys of consumer households, farmer households and scientists. A discrete choice approach was used to elicit the purchase intentions of the respondents. Two separate probit models were developed to examine the effect of various factors on the choices of the respondents. Bt cotton farmers had a very positive attitude because Bt cotton provided them with significant economic benefits. Chinese consumers from developed regions had a higher acceptance and willingness to pay for GM foods than consumers in other regions. The positive attitude toward GM foods by the scientific community will help to promote biotechnology in China in the future. Our survey emphasized that educational efforts made by government officials, the media and scientists can facilitate the acceptance of GM technology in China. Further educational efforts will be critical for influencing consumer attitudes and decisions of government agencies in the future. More effective educational efforts by government agencies and public media concerning the scientific facts and safety of GM foods would enhance the acceptance of GM crops in China.

  11. Attitudes in China about Crops and Foods Developed by Biotechnology.

    Directory of Open Access Journals (Sweden)

    Fei Han

    Full Text Available Transgenic Bt cotton has been planted in China since 1997 and, in 2009, biosafety certificates for the commercial production of Bt rice and phytase corn were issued by the Chinese government. The public attitude in China toward agricultural biotechnology and genetically modified (GM crops and foods has received considerable attention worldwide. We investigated the attitudes of consumers, Bt cotton farmers and scientists in China regarding GM crops and foods and the factors influencing their attitudes. Data were collected using interview surveys of consumer households, farmer households and scientists. A discrete choice approach was used to elicit the purchase intentions of the respondents. Two separate probit models were developed to examine the effect of various factors on the choices of the respondents. Bt cotton farmers had a very positive attitude because Bt cotton provided them with significant economic benefits. Chinese consumers from developed regions had a higher acceptance and willingness to pay for GM foods than consumers in other regions. The positive attitude toward GM foods by the scientific community will help to promote biotechnology in China in the future. Our survey emphasized that educational efforts made by government officials, the media and scientists can facilitate the acceptance of GM technology in China. Further educational efforts will be critical for influencing consumer attitudes and decisions of government agencies in the future. More effective educational efforts by government agencies and public media concerning the scientific facts and safety of GM foods would enhance the acceptance of GM crops in China.

  12. "Recombinant Protein of the Day": Using Daily Student Presentations to Add Real-World Aspects to a Biotechnology Course

    Science.gov (United States)

    Shaffer, Justin F.

    2013-01-01

    To provide a realistic view of the biotechnology industry for students, a novel course focusing on recombinant proteins and their importance in medicine, pharmaceuticals, industry, scientific research, and agriculture was developed. ''Designer Proteins and Society,'' an upper-division elective, was taught in the Fall 2012 semester to 16 junior,…

  13. Biotechnology: Commercialization and Economic Aspects, January 1993-June 1996. Quick Bibliography Series no. QB 96-10.

    Science.gov (United States)

    Leonard, Scott A., Comp.; Dobert, Raymond, Comp.

    This bibliography on the commercialization and economic aspects of biotechnology was produced by the National Agricultural Library. It contains 151 citations in English from the AGRICOLA database. The search strategy is included, call numbers are given for each entry, and abstracts are provided for some citations. The bibliography concludes with…

  14. European biotechnology. April 1978-July 1989 (Citations from the Life Sciences Collection data base). Report for April 1978-July 1989

    Energy Technology Data Exchange (ETDEWEB)

    1989-12-01

    This bibliography contains citations concerning agricultural and pharmaceutical biotechnical research and development being conducted by Western European nations. Topics include: the future of biotechnology, recent developments, genetic analysis and manipulation (biomolecular engineering), and the biological production of pesticides and medicinals. This bibliography will be especially useful to R D professionals and advanced biochemistry students entering the biomedical or agricultural fields. (Contains 134 citations fully indexed and including a title list.)

  15. Biotechnological applications of bacterial cellulases

    OpenAIRE

    Esther Menendez; Paula Garcia-Fraile; Raul Rivas

    2015-01-01

    Cellulases have numerous applications in several industries, including biofuel production, food and feed industry, brewing, pulp and paper, textile, laundry, and agriculture.Cellulose-degrading bacteria are widely spread in nature, being isolated from quite different environments. Cellulose degradation is the result of a synergic process between an endoglucanase, an exoglucanase and a,β-glucosidase. Bacterial endoglucanases degrade ß-1,4-glucan linkages of cellulose amorphous zones, mean...

  16. Biotechnology Education. Engaging the Learner: Embedding Information Literacy Skills into a Biotechnology Degree

    Science.gov (United States)

    Ward, Helena; Hockey, Julie

    2007-01-01

    One of the challenges of the Biotechnology industry is keeping up to date with the rapid pace of change and that much of the information, which students learn in their undergraduate studies, will be out of date in a few years. It is therefore crucial that Biotechnology students have the skills to access the relevant information for their studies…

  17. New Developments in Biotechnology: U.S. Investment in Biotechnology. [Special Report.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Office of Technology Assessment.

    Since the discovery of recombinant DNA in the early 1970s, biotechnology has become an essential tool for many industries. The potential of biotechnology to improve the Nation's health, food supply, and the quality of the environment leads logically to questions of whether current levels of investment in research and development, human resources,…

  18. New Developments in Biotechnology: U.S. Investment in Biotechnology. Summary.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Office of Technology Assessment.

    Since the discovery of recombinant DNA in the early 1970s, biotechnology has become an essential tool for many industries. The potential of biotechnology to improve the Nation's health, food supply, and the quality of the environment leads logically to questions of whether current levels of investment in research and development, human resources,…

  19. Life sciences today and tomorrow: emerging biotechnologies.

    Science.gov (United States)

    Williamson, E Diane

    2016-07-03

    The purpose of this review is to survey current, emerging and predicted future biotechnologies which are impacting, or are likely to impact in the future on the life sciences, with a projection for the coming 20 years. This review is intended to discuss current and future technical strategies, and to explore areas of potential growth during the foreseeable future. Information technology approaches have been employed to gather and collate data. Twelve broad categories of biotechnology have been identified which are currently impacting the life sciences and will continue to do so. In some cases, technology areas are being pushed forward by the requirement to deal with contemporary questions such as the need to address the emergence of anti-microbial resistance. In other cases, the biotechnology application is made feasible by advances in allied fields in biophysics (e.g. biosensing) and biochemistry (e.g. bio-imaging). In all cases, the biotechnologies are underpinned by the rapidly advancing fields of information systems, electronic communications and the World Wide Web together with developments in computing power and the capacity to handle extensive biological data. A rationale and narrative is given for the identification of each technology as a growth area. These technologies have been categorized by major applications, and are discussed further. This review highlights: Biotechnology has far-reaching applications which impinge on every aspect of human existence. The applications of biotechnology are currently wide ranging and will become even more diverse in the future. Access to supercomputing facilities and the ability to manipulate large, complex biological datasets, will significantly enhance knowledge and biotechnological development.

  20. Extremophilic micro-algae and their potential contribution in biotechnology.

    Science.gov (United States)

    Varshney, Prachi; Mikulic, Paulina; Vonshak, Avigad; Beardall, John; Wangikar, Pramod P

    2015-05-01

    Micro-algae have potential as sustainable sources of energy and products and alternative mode of agriculture. However, their mass cultivation is challenging due to low survival under harsh outdoor conditions and competition from other, undesired, species. Extremophilic micro-algae have a role to play by virtue of their ability to grow under acidic or alkaline pH, high temperature, light, CO2 level and metal concentration. In this review, we provide several examples of potential biotechnological applications of extremophilic micro-algae and the ranges of tolerated extremes. We also discuss the adaptive mechanisms of tolerance to these extremes. Analysis of phylogenetic relationship of the reported extremophiles suggests certain groups of the Kingdom Protista to be more tolerant to extremophilic conditions than other taxa. While extremophilic microalgae are beginning to be explored, much needs to be done in terms of the physiology, molecular biology, metabolic engineering and outdoor cultivation trials before their true potential is realized.

  1. Six priorities proposed for marine biotechnology in Denmark

    DEFF Research Database (Denmark)

    Børresen, Torger

    biochemical components. Complex structures with special properties can be included in pharmaceutical products, cosmetics and special foods. - Biofilm – from ships over the food industry to the interior of the human body. Biofilm is a deposit and growth of organisms on surfaces, usually with consequences......A survey initiated by the Ministry of Food, Agriculture and Fisheries in 2010 resulted in six priorities for the development of marine biotechnology in Denmark. Business opportunities were suggested and some elements for a successful strategy were proposed. The six priorities are the following....... Marine farming has the advantage that it does not impact freshwater resources. If established on land, water should be re-circulated and production limited to high priced species. - Healthy diet. Marine fatty acids, proteins, peptides and micronutrients are found in large quantities in marine organisms...

  2. Oil palm biotechnologies are definitely out of infancy

    Directory of Open Access Journals (Sweden)

    Rival Alain

    2010-11-01

    Full Text Available Although biotechnologies and sustainable development are often considered as antagonists, there is increasing evidence for a role for this approach in the ecological intensification of oil palm cultivation. Ecological intensification is based on the understanding of how nature functions so as to exploit its resources without destroying it. Living organisms are supported by the genome (DNA through the action of the transcriptome (RNAs, proteome, metabolome, and ionome, the four basic pillars of functional genomics. These pillars represent the sum of all the expressed genes, proteins, metabolites, and elements within an organism. The dynamic response and interaction of these biochemical “omes” defines how a living system functions, and its study, systems biology, is now one of the biggest challenges in life sciences. In oil palm, as in many major crops, functional genomics is still at its beginning, although there are no reasons why oil palm should not rapidly benefit from the fast progresses generated by automated and high-throughput technologies. The success of sequencing projects on model plants has created a widespread interest in exploring the structure and expression patterns of the genome. Indeed, several institutions have now achieved the full sequencing of the oil palm genome, paving the way for the rapid evolution of various genomics-based approaches. Oil palm breeding has provided an average 1% of genetic gain per year since the early 1960s and such an impressive increase in oil yield will be maintained in future generations with a major contribution from biotechnology. Indeed, the recent adoption of biotechnological approaches has already proven very useful in major areas such as cloning of outstanding material, identity checking of progenies/mother palms, identification and characterization of genes underlying agricultural traits, etc. Phenotypic differences among individuals are partly the result of quantitative differences in

  3. Medical Biotechnology: Problems and Prospects in Bangladesh

    Directory of Open Access Journals (Sweden)

    Shaikh Mizan

    2013-01-01

    Full Text Available Biotechnology is the knowledge and techniques of developing and using biological systems for deriving special products and services. The age-old technology took a new turn with the advent of recombinant DNA techniques, and boosted by the development of other molecular biological techniques, cell culture techniques and bioinformatics. Medical biotechnology is the major thrust area of biotechnology. It has brought revolutions in medicine – quick methods for diagnosing diseases, generation of new drugs and vaccines, completely novel approach of treatment are only a few to mention. The industrial and financial bulk of the industry mushroomed very rapidly in the last three decades, led by the USA and western advanced nations. Asian countries like China, India, South Korea, Taiwan and Singapore joined late, but advancing forward in a big way. In all the Asian countries governments supported the initiatives of the expert and entrepreneur community, and invested heavily in its development. Bangladesh has got great potential in developing biotechnology and reaping its fruits. However, lack of commitment and patriotism, and too much corruption and irresponsibility in political and bureaucratic establishment are the major hindrance to the development of biotechnology in Bangladesh.

  4. Forest biotechnology advances to support global bioeconomy

    Directory of Open Access Journals (Sweden)

    Antoine Harfouche

    2015-01-01

    Full Text Available The world is shifting to an innovation economy and forest biotechnology can play a major role in the bio-economy by providing farmers, producers, and consumers with tools that can better advance this transition. First-generation or conventional biofuels are primarily produced from food crops and are therefore limited in their ability to meet challenges for petroleum-product substitution and climate change mitigation, and to overcome the food-versus-fuel dilemma. In the longer term, forest lignocellulosic biomass will provide a unique renewable resource for large-scale production of bioenergy, biofuels and bio-products. These second-generation or advanced biofuels and bio-products have also the potential to avoid many of the issues facing the first-generation biofuels, particularly the competition concerning land and water used for food production. To expand the range of natural biological resources the rapidly evolving tools of biotechnology can ameliorate the conversion process, lower the conversion costs and also enhance target yield of forest biomass feedstock and the product of interest. Therefore, linking forest biotechnology with industrial biotechnology presents a promising approach to convert woody lignocellulosic biomass into biofuels and bio-products. Major advances and applications of forest biotechnology that are being achieved to competitively position forest biomass feedstocks with corn and other food crops are outlined. Finally, recommendations for future work are discussed.

  5. Case studies on the use of biotechnologies and on biosafety provisions in four African countries.

    Science.gov (United States)

    Black, Robert; Fava, Fabio; Mattei, Niccolo; Robert, Vincent; Seal, Susan; Verdier, Valerie

    2011-12-20

    This review is based on a study commissioned by the European Commission on the evaluation of scientific, technical and institutional challenges, priorities and bottlenecks for biotechnologies and regional harmonisation of biosafety in Africa. Biotechnology was considered within four domains: agricultural biotechnologies ('Green'), industrial biotechnologies and biotechnologies for environmental remediation ('White'), biotechnologies in aquaculture ('Blue') and biotechnologies for healthcare ('Red'). An important consideration was the decline in partnerships between the EU and developing countries because of the original public antipathy to some green biotechnologies, particularly genetically modified organisms (GMOs) and food from GM crops in Europe. The study focus reported here was West Africa (Ghana, Senegal, Mali and Burkina Faso). The overall conclusion was that whereas high-quality research was proceeding in the countries visited, funding is not sustained and there is little evidence of practical application of biotechnology and benefit to farmers and the wider community. Research and development that was being carried out on genetically modified crop varieties was concentrating on improving food security and therefore unlikely to have significant impact on EU markets and consumers. However, there is much non-controversial green biotechnology such as molecular diagnostics for plant and animal disease and marker-assisted selection for breeding that has great potential application. Regarding white biotechnology, it is currently occupying only a very small industrial niche in West Africa, basically in the sole sector of the production of liquid biofuels (i.e., bio-ethanol) from indigenous and locally planted biomass (very often non-food crops). The presence of diffused small-scale fish production is the basis to develop and apply new (Blue) aquaculture technologies and, where the research conditions and the production sector can permit, to increase this type of

  6. Biotechnology Approaches to Life Detection

    Science.gov (United States)

    Steele, Andrew; McKay, David; Schweitzer, Mary

    2001-01-01

    The direct detection of organic biomarkers for living or fossil microbes on Mars by an in situ instrument is a worthy goal for future lander missions. Several new and innovative biotechnology approaches are being explored. Firstly we have proposed an instrument based on immunological reactions to specific antibodies to cause activation of fluorescent stains. Antibodies are raised or acquired to a variety of general and specific substances that might be in Mars soil. These antibodies are then combined with various fluorescent stains and applied to micron sized numbered spots on a small (2-3 cm) test plate where they become firmly attached after freeze drying. Using technology that has been developed for gene mining in DNA technology up to 10,000 tests per square inch can now be applied to a test plate. On Mars or the planet/moon of interest, a sample of soil from a trench or drill core is extracted with water and/or an organic solvent and ultrasonication and then applied to the test plate. Any substance, which has an antibody on the test plate, will react with its antibody and activate its fluorescent stain. At the moment a small UV light source will illuminate the test plate, which is observed with a small CCD camera, although other detection systems will be applied. The numbered spots that fluoresce indicate the presence of the tested-for substance, and the intensity indicates relative amounts. Furthermore with up to a thousand test plates available false positives and several variations of antibody can also be screened for. The entire instrument can be quite small and light, on the order of 10 cm in each dimension. A possible choice for light source may be small UV lasers at several wavelengths. Some of the wells or spots can contain simply standard fluorescent stains used to detect live cells, dead cells, DNA, etc. The stains in these spots may be directly activated, with no antibodies being necessary. The proposed system will look for three classes of

  7. Perspectives on biotechnological applications of archaea

    Directory of Open Access Journals (Sweden)

    Chiara Schiraldi

    2002-01-01

    Full Text Available Many archaea colonize extreme environments. They include hyperthermophiles, sulfur-metabolizing thermophiles, extreme halophiles and methanogens. Because extremophilic microorganisms have unusual properties, they are a potentially valuable resource in the development of novel biotechnological processes. Despite extensive research, however, there are few existing industrial applications of either archaeal biomass or archaeal enzymes. This review summarizes current knowledge about the biotechnological uses of archaea and archaeal enzymes with special attention to potential applications that are the subject of current experimental evaluation. Topics covered include cultivation methods, recent achievements in genomics, which are of key importance for the development of new biotechnological tools, and the application of wild-type biomasses, engineered microorganisms, enzymes and specific metabolites in particular bioprocesses of industrial interest.

  8. Biotechnological Aspects of Microbial Extracellular Electron Transfer

    Science.gov (United States)

    Kato, Souichiro

    2015-01-01

    Extracellular electron transfer (EET) is a type of microbial respiration that enables electron transfer between microbial cells and extracellular solid materials, including naturally-occurring metal compounds and artificial electrodes. Microorganisms harboring EET abilities have received considerable attention for their various biotechnological applications, in addition to their contribution to global energy and material cycles. In this review, current knowledge on microbial EET and its application to diverse biotechnologies, including the bioremediation of toxic metals, recovery of useful metals, biocorrosion, and microbial electrochemical systems (microbial fuel cells and microbial electrosynthesis), were introduced. Two potential biotechnologies based on microbial EET, namely the electrochemical control of microbial metabolism and electrochemical stimulation of microbial symbiotic reactions (electric syntrophy), were also discussed. PMID:26004795

  9. Applications of Protein Hydrolysates in Biotechnology

    Science.gov (United States)

    Pasupuleti, Vijai K.; Holmes, Chris; Demain, Arnold L.

    By definition, protein hydrolysates are the products that are obtained after the hydrolysis of proteins and this can be achieved by enzymes, acid or alkali. This broad definition encompasses all the products of protein hydrolysis - peptides, amino acids and minerals present in the protein and acid/alkali used to adjust pH (Pasupuleti 2006). Protein hydrolysates contain variable side chains depending on the enzymes used. These side chains could be carboxyl, amino, imidazole, sulfhydryl, etc. and they may exert specific physiological roles in animal, microbial, insect and plant cells. This introductory chapter reviews the applications of protein hydrolysates in biotechnology. The word biotechnology is so broad and for the purpose of this book, we define it as a set of technologies such as cell culture technology, bioprocessing technology that includes fermentations, genetic engineering technology, microbiology, and so on. This chapter provides introduction and leads to other chapters on manufacturing and applications of protein hydrolysates in biotechnology.

  10. Biotechnological applications of extremophiles, extremozymes and extremolytes

    KAUST Repository

    Raddadi, Noura

    2015-08-14

    In the last decade, attention to extreme environments has increased because of interests to isolate previously unknown extremophilic microorganisms in pure culture and to profile their metabolites. Microorganisms that live in extreme environments produce extremozymes and extremolytes that have the potential to be valuable resources for the development of a bio-based economy through their application to white, red, and grey biotechnologies. Here, we provide an overview of extremophile ecology, and we review the most recent applications of microbial extremophiles and the extremozymes and extremolytes they produce to biotechnology.

  11. Protein engineering approaches to chemical biotechnology.

    Science.gov (United States)

    Chen, Zhen; Zeng, An-Ping

    2016-12-01

    Protein engineering for the improvement of properties of biocatalysts and for the generation of novel metabolic pathways plays more and more important roles in chemical biotechnology aiming at the production of chemicals from biomass. Although widely used in single-enzyme catalysis process, protein engineering is only being increasingly explored in recent years to achieve more complex in vitro and in vivo biocatalytic processes. This review focuses on major contributions of protein engineering to chemical biotechnology in the field of multi-enzymatic cascade catalysis and metabolic engineering. Especially, we discuss and highlight recent strategies for combining pathway design and protein engineering for the production of novel products.

  12. Needed: models of biotechnology intellectual property.

    Science.gov (United States)

    Gold, E Richard; Castle, David; Cloutier, L Martin; Daar, Abdallah S; Smith, Pamela J

    2002-08-01

    Although never uncontroversial, intellectual property rights in biotechnological innovation are once more the focus of intense debate. The debate has yet to reach any result, largely because of several important errors in the way that various disciplines approach it. These errors include making assumptions without empirical basis and conflating various intellectual property regimes. What is needed is a transdisciplinary integrated method to correct these errors. Such a method can be implemented through the construction of alternative models of intellectual property protection designed to balance the various social, ethical and economic constraints that affect biotechnology.

  13. Improving Technology Perception through Information and Education: A case of Biotechnology in Nigeria

    Directory of Open Access Journals (Sweden)

    Adegbenga Emmanuel Adekoya

    2008-12-01

    Full Text Available A study was conducted in two states in Nigeria (Edo and Delta as part of the International Institute of Tropical Agriculture Activities in the Niger Delta area of the south-western agro-ecological zone part of Nigeria. A workshop was organized for the sole purpose of presenting information on biotechnology as a discipline and as a necessary technology that can be safely adopted by even peasant farmers. Several areas of biotechnology such as biosafety,ethics, environmental and health safety where the audience can participate and explore were presented by speakers. Ninety-five participants at the workshop formed the respondents for the study and a questionnaire was designed to elicit information on the participants’ awareness, knowledge, perception and attitude about biotechnology and its products, before and after the workshop. The results showed that the age of the respondents ranged from 19 to 56 years with a mean of 41 years. Results also showed that all the participants, apart from 14.8 percent, had educational qualification higher than secondary school. Majority (63 percent were civil servants including 30 percent from Ministry of Agriculture and 33 percent from Agricultural Research Institutes, 24 percent from the academia and others from private organisations. Through workshop as an education method, there was change in perception after training. Before the workshop 67.4 percent of the respondents said they would eat food made from genetically engineered crops however, at the end of the workshop 80 percent of the same group of respondents indicated they will eat food made from genetically engineered crops. Using a paired sample t-test statistics, the test of difference on disposition before and after the workshop gave a t-value of 4.569 which was significant at 0.05 level. The study concludes that information dissemination through training method such as workshop has contributed to change in perception of biotechnology in Nigeria.

  14. Improving Technology Perception through Information and Education: A case of Biotechnology in Nigeria

    Directory of Open Access Journals (Sweden)

    Adegbenga Emmanuel ADEKOYA

    2008-12-01

    Full Text Available A study was conducted in two states in Nigeria (Edo and Delta as part of the International Institute of Tropical Agriculture Activities in the Niger Delta area of the south-western agro-ecological zone part of Nigeria. A workshop was organized for the sole purpose of presenting information on biotechnology as a discipline and as a necessary technology that can be safely adopted by even peasant farmers. Several areas of biotechnology such as biosafety,ethics, environmental and health safety where the audience can participate and explore were presented by speakers. Ninety-five participants at the workshop formed the respondents for the study and a questionnaire was designed to elicit information on the participants’ awareness, knowledge, perception and attitude about biotechnology and its products, before and after the workshop. The results showed that the age of the respondents ranged from 19 to 56 years with a mean of 41 years. Results also showed that all the participants, apart from 14.8 percent, had educational qualification higher than secondary school. Majority (63 percent were civil servants including 30 percent from Ministry ofAgriculture and 33 percent from Agricultural Research Institutes, 24 percent from the academia and others from private organisations. Through workshop as an education method, there was change in perception after training. Before the workshop 67.4 percent of the respondents said they would eat food made from genetically engineered crops however, at the end of the workshop 80 percent of the same group of respondents indicated they will eat food made from genetically engineered crops. Using a paired sample t-test statistics, the test of difference on disposition before and after the workshop gave a t-value of 4.569 which was significant at 0.05 level. The study concludes that information dissemination through training method such as workshop has contributed to change in perception of biotechnology in Nigeria.

  15. Beyond Conservation Agriculture

    Directory of Open Access Journals (Sweden)

    Ken E Giller

    2015-10-01

    Full Text Available Global support for Conservation Agriculture (CA as a pathway to Sustainable Intensification is strong. CA revolves around three principles: no-till (or minimal soil disturbance, soil cover, and crop rotation. The benefits arising from the ease of crop management, energy/cost/time savings and soil and water conservation led to widespread adoption of CA, particularly on large farms in the Americas and Australia, where farmers harness the tools of modern science: highly-sophisticated machines, potent agrochemicals and biotechnology. Over the past ten years CA has been promoted among smallholder farmers in the (sub- tropics, often with disappointing results. Growing evidence challenges the claims that CA increases crop yields and builds-up soil carbon although increased stability of crop yields in dry climates is evident. Our analyses suggest pragmatic adoption on larger mechanized farms, and limited uptake of CA by smallholder farmers in developing countries. We propose a rigorous, context-sensitive approach based on Systems Agronomy to analyze and explore sustainable intensification options, including the potential of CA. There is an urgent need to move beyond dogma and prescriptive approaches to provide soil and crop management options for farmers to enable the Sustainable Intensification of agriculture.

  16. Beyond conservation agriculture

    Science.gov (United States)

    Giller, Ken E.; Andersson, Jens A.; Corbeels, Marc; Kirkegaard, John; Mortensen, David; Erenstein, Olaf; Vanlauwe, Bernard

    2015-01-01

    Global support for Conservation Agriculture (CA) as a pathway to Sustainable Intensification is strong. CA revolves around three principles: no-till (or minimal soil disturbance), soil cover, and crop rotation. The benefits arising from the ease of crop management, energy/cost/time savings, and soil and water conservation led to widespread adoption of CA, particularly on large farms in the Americas and Australia, where farmers harness the tools of modern science: highly-sophisticated machines, potent agrochemicals, and biotechnology. Over the past 10 years CA has been promoted among smallholder farmers in the (sub-) tropics, often with disappointing results. Growing evidence challenges the claims that CA increases crop yields and builds-up soil carbon although increased stability of crop yields in dry climates is evident. Our analyses suggest pragmatic adoption on larger mechanized farms, and limited uptake of CA by smallholder farmers in developing countries. We propose a rigorous, context-sensitive approach based on Systems Agronomy to analyze and explore sustainable intensification options, including the potential of CA. There is an urgent need to move beyond dogma and prescriptive approaches to provide soil and crop management options for farmers to enable the Sustainable Intensification of agriculture. PMID:26579139

  17. Strategies to enable the adoption of animal biotechnology to sustainably improve global food safety and security.

    Science.gov (United States)

    Tizard, Mark; Hallerman, Eric; Fahrenkrug, Scott; Newell-McGloughlin, Martina; Gibson, John; de Loos, Frans; Wagner, Stefan; Laible, Götz; Han, Jae Yong; D'Occhio, Michael; Kelly, Lisa; Lowenthal, John; Gobius, Kari; Silva, Primal; Cooper, Caitlin; Doran, Tim

    2016-10-01

    The ability to generate transgenic animals has existed for over 30 years, and from those early days many predicted that the technology would have beneficial applications in agriculture. Numerous transgenic agricultural animals now exist, however to date only one product from a transgenic animal has been approved for the food chain, due in part to cumbersome regulations. Recently, new techniques such as precision breeding have emerged, which enables the introduction of desired traits without the use of transgenes. The rapidly growing human population, environmental degradation, and concerns related to zoonotic and pandemic diseases have increased pressure on the animal agriculture sector to provide a safe, secure and sustainable food supply. There is a clear need to adopt transgenic technologies as well as new methods such as gene editing and precision breeding to meet these challenges and the rising demand for animal products. To achieve this goal, cooperation, education, and communication between multiple stakeholders-including scientists, industry, farmers, governments, trade organizations, NGOs and the public-is necessary. This report is the culmination of concepts first discussed at an OECD sponsored conference and aims to identify the main barriers to the adoption of animal biotechnology, tactics for navigating those barriers, strategies to improve public perception and trust, as well as industry engagement, and actions for governments and trade organizations including the OECD to harmonize regulations and trade agreements. Specifically, the report focuses on animal biotechnologies that are intended to improve breeding and genetics and currently are not routinely used in commercial animal agriculture. We put forward recommendations on how scientists, regulators, and trade organizations can work together to ensure that the potential benefits of animal biotechnology can be realized to meet the future needs of agriculture to feed the world.

  18. Biotechnology for site restoration: scope of the problem

    Energy Technology Data Exchange (ETDEWEB)

    Bitchaeva, O.

    1996-09-18

    The potential of modern biotechnology for solving problems related with the nuclear industry, especially site restoration, are investigated. The advantages of biotechnology, the current applications in Russia, main points of international collaboration, and political considerations are discussed.

  19. What Ideas Do Students Associate with "Biotechnology" and "Genetic Engineering"?

    Science.gov (United States)

    Hill, Ruaraidh; Stanisstreet, Martin; Boyes, Edward

    2000-01-01

    Explores the ideas that students aged 16-19 associate with the terms 'biotechnology' and 'genetic engineering'. Indicates that some students see biotechnology as risky whereas genetic engineering was described as ethically wrong. (Author/ASK)

  20. Update to the Coordinated Framework for the Regulation of Biotechnology

    Science.gov (United States)

    This Update to the Coordinated Framework for the Regulation of Biotechnology updates earlier versions from 1986 and 1992 is intended to clarify the current roles and responsibilities of agencies involved in the regulation of biotechnology products.

  1. National Strategy for Modernizing the Regulatory System for Biotechnology Products

    Science.gov (United States)

    This National Strategy for Modernizing the Regulatory System for Biotechnology Products sets forth a vision for ensuring that the federal regulatory system is prepared to efficiently assess the risks, if any, of the future products of biotechnology.

  2. White House Announcement on the Regulation of Biotechnology

    Science.gov (United States)

    The White House posted a blog unveiling documents as part of the Administration’s continuing effort to modernize the federal regulatory system for biotechnology products as well as clarify various roles of the EPA, FDA in evaluating new biotechnologies.

  3. Advances in optics for biotechnology, medicine and surgery

    OpenAIRE

    Fitzmaurice, Maryann; Pogue, Brian W.; Tearney, Guillermo J.; Tunnell, James W.; Yang, Changhuei

    2014-01-01

    The editors introduce the Biomedical Optics Express feature issue, “Advances in Optics for Biotechnology, Medicine and Surgery,” which includes 12 contributions from attendees of the 2011 conference Advances in Optics for Biotechnology, Medicine and Surgery XII.

  4. Advances in optics for biotechnology, medicine and surgery.

    Science.gov (United States)

    Hillman, Elizabeth M C; Elson, Daniel S; Bigio, Irving J; Levenson, Richard M; So, Peter T C

    2012-03-01

    The editors introduce the Biomedical Optics Express feature issue, "Advances in Optics for Biotechnology, Medicine and Surgery," which includes 12 contributions from attendees of the 2011 conference Advances in Optics for Biotechnology, Medicine and Surgery XII.

  5. Initiatives on a sustainable development strategy for Finnish biotechnology

    OpenAIRE

    Hermans, Raine; Kulvik, Martti

    2005-01-01

    The need for the strategic initiatives for biotechnology strategy emerged in interviews with 90 Finnish biotechnology leaders in the ETLA Biotechnology Survey, conducted at the end of 2004. This paper discusses on the policy implications for the project on “The biotechnology industry as a part of the Finnish National Innovation System” financed by Tekes, the National Technology Agency of Finland. Tekes has strongly encouraged the formation of policy implications and strategic initiatives for ...

  6. Transgenic agriculture and environmental indicators

    Directory of Open Access Journals (Sweden)

    Denize Dias de Carvalho

    2006-12-01

    Full Text Available Despite the rapid diffusion of transgenic crops, there are still few environmental impact studies capable of supplying a conclusive scientific response in regard to its technical and economic advantages and disadvantages. Prospective scenarios were elaborated to assist environmental impact assessment, using techniques derived from SWOT (Strength, Weakness, Opportunity, Threat analysis and the DPSIR (Driving Force – human activity, Pressure, State, Impact, Response model, to evaluate the environmental indicators and the relationship between them. Control and management actions were identified, searching the integration of aspects related to the biotechnology applied to transgenic processes, biodiversity, biosafety and intellectual property. It was demonstrated that the DPSIR model is, in fact, an instrument for integrated environmental assessment and the application of the proposed methodology resulted in favorable indicators to the adoption of transgenic agriculture. The elaborated scenarios are useful to develop an Environmental Management System (EMS to agriculture.

  7. High School Students' Knowledge and Attitudes regarding Biotechnology Applications

    Science.gov (United States)

    Ozel, Murat; Erdogan, Mehmet; Usak, Muhammet; Prokop, Pavol

    2009-01-01

    The purpose of this study was to investigate high school students' knowledge and attitudes regarding biotechnology and its various applications. In addition, whether students' knowledge and attitudes differed according to age and gender were also explored. The Biotechnology Knowledge Questionnaire (BKQ) with 16 items and the Biotechnology Attitude…

  8. Environmental Biotechnology Research and Development Program 1989-1992

    NARCIS (Netherlands)

    Brinkman J; Rulkens WH; Visscher K

    1989-01-01

    This report is an English translation of the Dutch Research and Development Program on environmental biotechnology 1989-1992. In this program an overview is given of the recent developments in environmental biotechnology. Based on this overview, the possibilities of biotechnology for management

  9. Biologically Fit: Using Biotechnology to Create a Better Soldier

    Science.gov (United States)

    2013-12-01

    Russia , and North Korea have commercial biotechnology facilities and possess the capabilities to conduct advanced research. Therefore, with U.S...USING BIOTECHNOLOGY TO CREATE A BETTER SOLDIER by Christina M. Buchner December 2013 Thesis Advisor: James Russell Second Reader...DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE BIOLOGICALLY FIT: USING BIOTECHNOLOGY TO CREATE A BETTER SOLDIER 5. FUNDING NUMBERS 6

  10. Biotechnology System Facility: Risk Mitigation on Mir

    Science.gov (United States)

    Gonda, Steve R., III; Galloway, Steve R.

    2003-01-01

    NASA is working with its international partners to develop space vehicles and facilities that will give researchers the opportunity to conduct scientific investigations in space. As part of this activity, NASA's Biotechnology Cell Science Program (BCSP) at the Johnson Space Center (JSC) is developing a world-class biotechnology laboratory facility for the International Space Station (ISS). This report describes the BCSP, including the role of the BTS. We identify the purpose and objectives of the BTS and a detailed description of BTS facility design and operational concept, BTS facility and experiment-specific hardware, and scientific investigations conducted in the facility. We identify the objectives, methods, and results of risk mitigation investigations of the effects of microgravity and cosmic radiation on the BTS data acquisition and control system. These results may apply to many other space experiments that use commercial, terrestrial-based data acquisition technology. Another focal point is a description of the end-to-end process of integrating and operating biotechnology experiments on a variety of space vehicles. The identification of lessons learned that can be applied to future biotechnology experiments is an overall theme of the report. We include a brief summary of the science results, but this is not the focus of the report. The report provides some discussion on the successful 130-day tissue engineering experiment performed in BTS on Mir and describes a seminal gene array investigation that identified a set of unique genes that are activated in space.

  11. Opportunities for energy conservation through biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Young, J.K.; Griffin, E.A.; Russell, J.A.

    1984-11-01

    The purpose of this study is to identify and quantify potential energy savings available through the development and application of biotechnologies. This information is required in support of ECUT research planning efforts as an aid in identifying promising areas needing further consideration and development. It is also intended as background information for a companion ECUT study being conducted by the National Academy of Science to evaluate the use of bioprocessing methods to conserve energy. Several studies have been conducted recently to assess the status and implications of the development of biotechnology. The Office of Technology Assessment (OTA) considered institutional, economic, and scientific problems and barriers. The National Science Foundation sponsored a study to examine regulatory needs for this new and expanding technology. Somewhat in contrast to these studies, this report covers principally the technical issues. It should be emphasized that the practicality of many developments in biotechnology is not evaluated solely on the basis of energy considerations. Bioprocesses must often compete with well-established coal, petroleum, and natural gas technologies. A complete evaluation of the technical, economical, and ecological impacts of the large-scale applications discussed in this report is not possible within the scope of this study. Instead, this report assesses the potential of biotechnology to save energy so that research into all aspects of implementation will be stimulated for those industries with significant energy savings potential. 92 references, 6 figures, 24 tables.

  12. Biotechnology Education in India: An Overview

    Science.gov (United States)

    Joshi, Kirti; Mehra, Kavita; Govil, Suman; Singh, Nitu

    2013-01-01

    Among the developing countries, India is one of those that recognises the importance of biotechnology. The trajectory of different policies being formulated over time is proof that the government is progressing towards achieving self-sufficiency. However, to cater to the ever-growing biotech industry, skilled manpower is required. This article…

  13. Personality and Impersonality in Biotechnology Discourse

    DEFF Research Database (Denmark)

    Lassen, Inger

    2006-01-01

    With the emergence of biotechnology, the field account has been replaced by something that we may refer to as a laboratory account - a kind of narrative that constitutes the Materials and Methods section of the IMRD model (introduction, methods, results and discussion). Research focusing on field...

  14. Novel gene expression tools for rice biotechnology

    Science.gov (United States)

    Biotechnology is an effective and important method of improving both quality and agronomic traits in rice. We are developing novel molecular tools for genetic engineering, with a focus on developing novel transgene expression control elements (i.e. promoters) for rice. A suite of monocot grass promo...

  15. Chemical hazards in the biotechnology industry.

    Science.gov (United States)

    Ducatman, A M; Coumbis, J J

    1991-01-01

    The modern biotechnology industry employs thousands of people and is growing rapidly. The numbers of toxic chemicals encountered are substantial and the applications are largely novel. Health care professionals face a formidable task in identifying occupational hazards and safeguarding the health of employees.

  16. Editorial: Biotechnology's impact on sustainable development.

    Science.gov (United States)

    Jungbauer, Alois; Lee, Sang Yup

    2012-11-01

    Biotechnology is increasingly recognized in society as a technology to improve the quality of life in a sustainable manner. It is clear that bioenergy and biofuel cannot solve a world energy crisis or reverse global warming, but from a local perspective it can contribute a lot.

  17. Final report, International Symposium on Environmental Biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Wise, Donald L.

    2000-03-20

    This meeting included technical presentations of state-of-the-art research which were integrated with tutorials and workshops by practicing technologies in the broad field of environmental biotechnology. This meeting was designed to be, in every respect, truly global. Over 150 excellent abstracts from around the world were accepted. For example, presentations were heard from technical workers in Southeast Asia, Russia, China, Europe, North Africa, India, and the US. By having these selected presenters, as well as identified experienced tutors with focused workshops, all participants benefited from this interactive symposium. A number of social events further promoted informal exchange of ideas, discussions of technical problems, and exploration of new applications. This international symposium on environmental biotechnology was on the campus of Northeastern University but all Boston area universities were included and participated using designed conference Co-Chairs. This symposium, with an attendance of several hundred people, was considered a major success. Workers with experience in one area of environmental biotechnology learned from the wealth of established backgrounds of those in other areas of environmental biotechnology. To formally disseminate conference results, it was pre-arranged that all technical presentations were reviewed for formal publications.

  18. [The new Colombian criminal code and biotechnology].

    Science.gov (United States)

    González de Cancino, Emilssen

    2002-01-01

    The author describes the process by which new offenses concerning biotechnology have been included in Colombia's Penal Code and discusses some of the more controversial aspects involved. She examines the various stages of the passage of the Bill through Parliament and the modifications undergone. She also provides well-argued criticism of the text, with appropriate reference to Constitutional provisions regarding the rights concerned.

  19. Biotechnologizing Jatropha for local sustainable development

    NARCIS (Netherlands)

    Puente, D.

    2010-01-01

    This article explores whether and how the biotechnologization process that the fuel-plant Jatropha curcas is undergoing might strengthen local sustainable development. It focuses on the ongoing efforts of the multi-stakeholder network Gota Verde to harness Jatropha within local small-scale productio

  20. The Brave New World of Biotechnology

    Science.gov (United States)

    Reese, Susan

    2004-01-01

    Is it the science that will save the world from starvation, or will it mean the end of the world as it is known? While some people fear genetically altered "Frankenfoods" and DNA experiments with pathogenic microorganisms that could result in worldwide epidemics, others view biotechnology as using biological organisms to make products that benefit…

  1. Realizing the promises of marine biotechnology

    NARCIS (Netherlands)

    Luiten, EEM; Akkerman, [No Value; Koulman, A; Kamermans, P; Reith, H; Barbosa, MJ; Sipkema, D; Wijffels, RH

    2003-01-01

    High-quality research in the field of marine biotechnology is one of the key-factors for successful innovation in exploiting the vast diversity of marine life. However, fascinating scientific research with promising results and claims on promising potential applications (e.g. for pharmaceuticals, nu

  2. Public Germplasm Collections and Revolutions in Biotechnology

    Science.gov (United States)

    Public germplasm collections provided the biological material critical for launching the three most important revolutions in modern biotechnology: (i) An isolate of Penicillium chrysogenum, NRRL 1951, the basis for industrial production of penicillan, originated from the ARS Culture Collection in Pe...

  3. Plant synthetic biology: a new platform for industrial biotechnology.

    Science.gov (United States)

    Fesenko, Elena; Edwards, Robert

    2014-05-01

    Thirty years after the production of the first generation of genetically modified plants we are now set to move into a new era of recombinant crop technology through the application of synthetic biology to engineer new and complex input and output traits. The use of synthetic biology technologies will represent more than incremental additions of transgenes, but rather the directed design of completely new metabolic pathways, physiological traits, and developmental control strategies. The need to enhance our ability to improve crops through new engineering capability is now increasingly pressing as we turn to plants not just for food, but as a source of renewable feedstocks for industry. These accelerating and diversifying demands for new output traits coincide with a need to reduce inputs and improve agricultural sustainability. Faced with such challenges, existing technologies will need to be supplemented with new and far-more-directed approaches to turn valuable resources more efficiently into usable agricultural products. While these objectives are challenging enough, the use of synthetic biology in crop improvement will face public acceptance issues as a legacy of genetically modified technologies in many countries. Here we review some of the potential benefits of adopting synthetic biology approaches in improving plant input and output traits for their use as industrial chemical feedstocks, as linked to the rapidly developing biorefining industry. Several promising technologies and biotechnological targets are identified along with some of the key regulatory and societal challenges in the safe and acceptable introduction of such technology.

  4. Ethical limitations in patenting biotechnological inventions.

    Science.gov (United States)

    Lugagnani, V

    1999-01-01

    In order to connect ethical considerations with practical limits to patentability, the moral judgement should possibly move from the exploitation of the invention to the nature and/or objectives of Research and Development (R&D) projects which have produced it: in other words, it appears quite reasonable and logical that Society is not rewarding unethical R&D activities by granting intellectual property rights. As far as biotechnology R&D is concerned, ethical guidance can be derived from the 1996 Council of EuropeOs OConvention for the protection of human rights and dignity of the human being with regard to the application of biology and medicineO, whose Chapter V - Scientific research - provides guidelines on: i. protection of persons undergoing research (e.g. informed consent); ii. protection of persons not able to consent to research; iii. research on embryos in vitro. As far as the specific point of patenting biotechnology inventions is concerned, the four exclusions prescribed by Directive 98/44/EC (i.e. human cloning, human germ-line gene therapy, use of human embryos for commercial purposes, unjustified animal suffering for medical purposes) are all we have in Europe in terms of ethical guidance to patentability. In Italy, in particular, we certainly need far more comprehensive legislation, expressing SocietyOs demand to provide ethical control of modern biotechnology. However it is quite difficult to claim that ethical concerns are being raised by currently awarded biotechnology patents related to living organisms and material thereof; they largely deal with the results of genomic R&D, purposely and usefully oriented toward improving health-care and agri-food processes, products and services. ONo patents on lifeOO can be an appealing slogan of militants against modern biotechnology, but it is far too much of an over-simplified abstraction to become the Eleventh Commandment our Society.

  5. Advanced Manufacturing and Value-added Products from US Agriculture

    Science.gov (United States)

    Villet, Ruxton H.; Child, Dennis R.; Acock, Basil

    1992-01-01

    An objective of the US Department of Agriculture (USDA) Agriculture Research Service (ARS) is to develop technology leading to a broad portfolio of value-added marketable products. Modern scientific disciplines such as chemical engineering are brought into play to develop processes for converting bulk commodities into high-margin products. To accomplish this, the extremely sophisticated processing devices which form the basis of modern biotechnology, namely, genes and enzymes, can be tailored to perform the required functions. The USDA/ARS is a leader in the development of intelligent processing equipment (IPE) for agriculture in the broadest sense. Applications of IPE are found in the production, processing, grading, and marketing aspects of agriculture. Various biotechnology applications of IPE are discussed.

  6. Can plant biotechnology help break the HIV-malaria link?

    Science.gov (United States)

    Vamvaka, E; Twyman, R M; Christou, P; Capell, T

    2014-01-01

    The population of sub-Saharan Africa is at risk from multiple, poverty-related endemic diseases. HIV and malaria are the most prevalent, but they disproportionately affect different groups of people, i.e. HIV predominantly affects sexually-active adults whereas malaria has a greater impact on children and pregnant women. Nevertheless, there is a significant geographical and epidemiological overlap which results in bidirectional and synergistic interactions with important consequences for public health. The immunosuppressive effects of HIV increase the risk of infection when individuals are exposed to malaria parasites and also the severity of malaria symptoms. Similarly, acute malaria can induce a temporary increase in the HIV viral load. HIV is associated with a wide range of opportunistic infections that can be misdiagnosed as malaria, resulting in the wasteful misuse of antimalarial drugs and a failure to address the genuine cause of the disease. There is also a cumulative risk of toxicity when antiretroviral and antimalarial drugs are given to the same patients. Synergistic approaches involving the control of malaria as a strategy to fight HIV/AIDS and vice versa are therefore needed in co-endemic areas. Plant biotechnology has emerged as a promising approach to tackle poverty-related diseases because plant-derived drugs and vaccines can be produced inexpensively in developing countries and may be distributed using agricultural infrastructure without the need for a cold chain. Here we explore some of the potential contributions of plant biotechnology and its integration into broader multidisciplinary public health programs to combat the two diseases in developing countries.

  7. Editorial: from plant biotechnology to bio-based products.

    Science.gov (United States)

    Stöger, Eva

    2013-10-01

    From plant biotechnology to bio-based products - this Special Issue of Biotechnology Journal is dedicated to plant biotechnology and is edited by Prof. Eva Stöger (University of Natural Resources and Life Sciences, Vienna, Austria). The Special Issue covers a wide range of topics in plant biotechnology, including metabolic engineering of biosynthesis pathways in plants; taking advantage of the scalability of the plant system for the production of innovative materials; as well as the regulatory challenges and society acceptance of plant biotechnology.

  8. Identification of Chromobacterium violaceum genes with potential biotechnological application in environmental detoxification.

    Science.gov (United States)

    Carepo, Marta S P; Azevedo, Juliana S Nina de; Porto, Jorge I R; Bentes-Sousa, Alexandra R; Batista, Jacqueline da Silva; Silva, Artur L C da; Schneider, Maria P C

    2004-01-01

    Chromobacterium violaceum is a Gram-negative bacterium found in a wide variety of tropical and subtropical ecosystems. The complete genome sequence of C. violaceum ATCC 12472 is now available, and it has considerable biotechnological potential for various applications, such as environmental detoxification, as well as medical and agricultural use. We examined the biotechnological potential of C. violaceum for environmental detoxification. Three operons, comprising the ars operon, involved in arsenic resistance, the cyn operon, involved in cyanate detoxification, and the hcn operon, encoding a cyanase, responsible for biogenic production of cyanide, as well as an open reading frame, encoding an acid dehalogenase, were analyzed in detail. Probable catalytic mechanisms for the enzymes were determined, based on amino acid sequence comparisons and on published structural information for these types of proteins.

  9. Applications for biotechnology: present and future improvements in lactic acid bacteria.

    Science.gov (United States)

    McKay, L L; Baldwin, K A

    1990-09-01

    The lactic acid bacteria are involved in the manufacture of fermented foods from raw agricultural materials such as milk, meat, vegetables, and cereals. These fermented foods are a significant part of the food processing industry and are often prepared using selected strains that have the ability to produce desired products or changes efficiently. The application of genetic engineering technology to improve existing strains or develop novel strains for these fermentations is an active research area world-wide. As knowledge about the genetics and physiology of lactic acid bacteria accumulates, it becomes possible to genetically construct strains with characteristics shaped for specific purposes. Examples of present and future applications of biotechnology to lactic acid bacteria to improve product quality are described. Studies of the basic biology of these bacteria are being actively conducted and must be continued, in order for the food fermentation industry to reap the benefits of biotechnology.

  10. Gender differences in knowledge and attitude towards biotechnology.

    Science.gov (United States)

    Simon, Richard M

    2010-11-01

    The relationship between gender, knowledge of biotechnology, attitudes toward biotechnology, and various socio-demographic variables was investigated using the Eurobarometer 52.1. It was found that neither socio-demographics, nor differing levels of scientific knowledge could explain females' greater probability of being pessimistic toward biotechnology. After running separate models for males and females, it was discovered that, for males, more knowledge of biotechnology decreased their probability of being pessimistic about science, but for females more knowledge of biotechnology actually lead to a greater probability of being pessimistic. Further, a gender-education interaction was discovered that revealed that, for males, education and knowledge of biotechnology have independent effects on attitudes, but for females education has no effect on attitudes towards biotechnology when knowledge is controlled. The results for females complicate the deficit model of social support for science, which posits that more knowledge of science always leads to more positive attitudes.

  11. Constraints on the development of biotechnology in Zambia.

    Science.gov (United States)

    Lewanika, M M; Mulenga, K D

    1996-09-01

    Biotechnology can play an essential role in fostering the economic and social development of developing countries like Zambia. However, due to a number of constraints, Zambia is not in a position to exploit the emerging opportunities from biotechnology. Prominent among these constraints are the lack of a biotechnology policy, an insufficient number of trained personnel, a poor science and technology base and very little basic research in universities and research institutions. The challenge Zambia must overcome is to establish a capacity and capability to innovate its own biotechnology as well as to adapt biotechnologies developed elsewhere to the Zambian conditions and environment. Despite all the hurdles and setbacks Zambia will face as she endeavours to enter the world of biotechnology, Zambia cannot afford to be a mere spectator as the rest of the world invests and benefits from the promise of biotechnology.

  12. Technical Update for Vocational Agriculture Teachers in Secondary Schools. Final Report.

    Science.gov (United States)

    Iowa State Univ. of Science and Technology, Ames. Dept. of Agricultural Education.

    A project provided ongoing opportunities for teachers in Iowa to upgrade their expertise in agribusiness management using new technology; production, processing, and marketing agricultural products; biotechnology in agriculture; and conservation of natural resources. The project also modeled effective teaching methods and strategies. Project…

  13. Agricultural Geophysics

    Science.gov (United States)

    The four geophysical methods predominantly used for agricultural purposes are resistivity, electromagnetic induction, ground penetrating radar (GPR), and time domain reflectometry (TDR). Resistivity and electromagnetic induction methods are typically employed to map lateral variations of apparent so...

  14. Biotechnology and DNA vaccines for aquatic animals

    Science.gov (United States)

    Kurath, G.

    2008-01-01

    Biotechnology has been used extensively in the development of vaccines for aquaculture. Modern molecular methods such as polymerase chain reaction (PCR), cloning and microarray analysis have facilitated antigen discovery, construction of novel candidate vaccines, and assessments of vaccine efficacy, mode of action, and host response. This review focuses on DNA vaccines for finfish to illustrate biotechnology applications in this field. Although DNA vaccines for fish rhabdoviruses continue to show the highest efficacy, DNA vaccines for several other viral and bacterial fish pathogens have now been proven to provide significant protection against pathogen challenge. Studies of the fish rhabdovirus DNA vaccines have elucidated factors that affect DNA vaccine efficacy as well as the nature of the fish innate and adaptive immune responses to DNA vaccines. As tools for managing aquatic animal disease emergencies, DNA vaccines have advantages in speed, flexibility, and safety, and one fish DNA vaccine has been licensed.

  15. Recent advances of metabolomics in plant biotechnology.

    Science.gov (United States)

    Okazaki, Yozo; Saito, Kazuki

    2012-01-01

    Biotechnology, including genetic modification, is a very important approach to regulate the production of particular metabolites in plants to improve their adaptation to environmental stress, to improve food quality, and to increase crop yield. Unfortunately, these approaches do not necessarily lead to the expected results due to the highly complex mechanisms underlying metabolic regulation in plants. In this context, metabolomics plays a key role in plant molecular biotechnology, where plant cells are modified by the expression of engineered genes, because we can obtain information on the metabolic status of cells via a snapshot of their metabolome. Although metabolome analysis could be used to evaluate the effect of foreign genes and understand the metabolic state of cells, there is no single analytical method for metabolomics because of the wide range of chemicals synthesized in plants. Here, we describe the basic analytical advancements in plant metabolomics and bioinformatics and the application of metabolomics to the biological study of plants.

  16. Metagenomics: advances in ecology and biotechnology.

    Science.gov (United States)

    Steele, Helen L; Streit, Wolfgang R

    2005-06-15

    This review highlights the significant advances which have been made in prokaryotic ecology and biotechnology due to the application of metagenomic techniques. It is now possible to link processes to specific microorganisms in the environment, such as the detection of a new phototrophic process in marine bacteria, and to characterise the metabolic cooperation which takes place in mixed species biofilms. The range of prokaryote derived products available for biotechnology applications is increasing rapidly. The knowledge gained from analysis of biosynthetic pathways provides valuable information about enzymology and allows engineering of biocatalysts for specific processes. The expansion of metagenomic techniques to include alternative heterologous hosts for gene expression and the development of sophisticated assays which enable screening of thousands of clones offers the possibility to find out even more valuable information about the prokaryotic world.

  17. Biotechnology/materials: The growing interface

    Science.gov (United States)

    Decker, Raymond F.

    1986-01-01

    The biotechnology/materials interaction dates back 3.5 billion years, yet today offers novel challenges for human creativity. The materials cycle practiced by microorganisms is compared to that recently practiced by humans. The processes of the biotechnology materials cycle are biogenesis, bioleaching, biofouling, biocorrosion, biodeterioration, and bioaccumulation. Each process is examined for mechanisms, scale of effect, and opportunity for creative human intervention or utilization. More than 50 of our metallic elements are bio-processed in nature. A like number of biogenic materials have been identified, with some at production rates of trillions of kg per annum (p.a.). Microorganisms can substitute for energy, capital, and labor. Over the eons, microorganisms have gained special attributes that now offer creative humans a new era of partnership in materials processing.

  18. Cyanobacterial genomics for ecology and biotechnology.

    Science.gov (United States)

    Hess, Wolfgang R

    2011-10-01

    Cyanobacteria are the only prokaryotes that directly convert solar energy and CO(2) into organic matter by oxygenic photosynthesis, explaining their relevance for primary production in many ecosystems and the increasing interest for biotechnology. At present, there are more than 60 cyanobacteria for which a total genome sequence is publicly available. These cyanobacteria belong to different lifestyles and origins, coming from marine and freshwater aquatic environments, as well as terrestrial and symbiotic habitats. Genome sizes vary by a factor of six, from 1.44 Mb to 9.05 Mb, with the number of reported genes ranging from 1241 to 8462. Several studies have demonstrated how these sequences could be used to successfully infer important ecological, physiological and biotechnologically relevant characteristics. However, sequences of cyanobacterial origin also comprise a significant portion of certain metagenomes. Moreover, genome analysis has been employed for culture-independent approaches and for resequencing mutant strains, a very recent tool in cyanobacterial research.

  19. Application of biotechnology for reproductive manipulation

    OpenAIRE

    1998-01-01

    For the efficient increase in the number of farm animals and for the improvement of amounts and quality of animal products such as wool, meat and milk, biotechnological new techniques of animal production have been developed and practically applied specifically concerning on the following subjects : (1). Artificial insemination (AI) is not a new technique, but the technique itself has been dramatically improved year by year and an epoch-making technique, deep freezing of semen was devised dur...

  20. Biosurfactants: Promising Molecules for Petroleum Biotechnology Advances

    OpenAIRE

    Darne G. Almeida; Soares Da Silva, Rita de Cássia F.; Luna, Juliana M.; Raquel D. Rufino; Santos, Valdemir A.; Ibrahim M Banat; Sarubbo, Leonie A.

    2016-01-01

    The growing global demand for sustainable technologies that improves the efficiency of petrochemical processes in the oil industry has driven advances in petroleum biotechnology in recent years. Petroleum industry uses substantial amounts of petrochemical-based synthetic surfactants in its activities as mobilizing agents to increase the availability or recovery of hydrocarbons as well as many other applications related to extraction, treatment, cleaning, and transportation. However, biosurfac...

  1. Biosurfactants: Promising Molecules for Petroleum Biotechnology Advances

    OpenAIRE

    DARNE GERMANO DE ALMEIDA; Rita De Cássia Freire Soares da Silva; Juliana Moura Luna; Raquel Diniz Rufino; Valdemir Alexandre Santos; Ibrahim M Banat; Leonie Asfora Sarubbo

    2016-01-01

    The growing global demand for sustainable technologies that improves the efficiency of petrochemical processes in the oil industry has driven advances in petroleum biotechnology in recent years. Petroleum industry uses substantial amounts of petrochemical-based synthetic surfactants in its activities as mobilizing agents to increase the availability or recovery of hydrocarbons as well as many other applications related to extraction, treatment, cleaning and transportation. However, biosurfact...

  2. Applications of yeast flocculation in biotechnological processes

    OpenAIRE

    Domingues, Lucília; Vicente, A.A.; Lima, Nelson; Teixeira, J. A.

    2000-01-01

    A review on the main aspects associated with yeast flocculation and its application in biotechnological processes is presented. This subject is addressed following three main aspects – the basics of yeast flocculation, the development of “new” flocculating yeast strains and bioreactor development. In what concerns the basics of yeast flocculation, the state of the art on the most relevant aspects of mechanism, physiology and genetics of yeast flocculation is reported. The const...

  3. Microencapsulation in food science and biotechnology.

    Science.gov (United States)

    Nazzaro, Filomena; Orlando, Pierangelo; Fratianni, Florinda; Coppola, Raffaele

    2012-04-01

    Microencapsulation can represent an excellent example of microtechnologies applied to food science and biotechnology. Microencapsulation can be successfully applied to entrap natural compounds, like essential oils or vegetal extracts containing polyphenols with well known antimicrobial properties to be used in food packaging. Microencapsulation preserves lactic acid bacteria, both starters and probiotics, in food and during the passage through the gastrointestinal tract, and may contribute to the development of new functional foods.

  4. Center of Excellence in Biotechnology (Research)

    Science.gov (United States)

    1993-03-01

    student L. Sweeney. BEST AVAILABLE BEST AVAILABLE COPY 2 Grant DAAL03-87-K-0004 ARO Center of Excellence in Biotechnology 1936 -1992 4. A. Statement of...was determined by NMR spectroscopy and refined by energy minimization with restraints. Fellow: Julio J. Mulero Advisor:. Thmas D. Fox Project Tide...Biochemistry/Chemistry Vikram Narasimhan Graduate - Biochemistry/Chemistry Julio J. Mulero ARO Fellow - Biochemistry/Genetics Lisa M. Sweeney ARO Fellow

  5. Ergonomics problems and solutions in biotechnology laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Coward, T.W.; Stengel, J.W.; Fellingham-Gilbert, P.

    1995-03-01

    The multi-functional successful ergonomics program currently implemented at Lawrence Livermore National Laboratory (LLNL) will be presented with special emphasis on recent findings in the Biotechnology laboratory environment. In addition to a discussion of more traditional computer-related repetitive stress injuries and associated statistics, the presentation will cover identification of ergonomic problems in laboratory functions such as pipetting, radiation shielding, and microscope work. Techniques to alleviate symptoms and prevent future injuries will be presented.

  6. The Development of TALE Nucleases for Biotechnology

    OpenAIRE

    Ousterout, David G.; Gersbach, Charles A

    2016-01-01

    The development of a facile genome engineering technology based on transcription activator-like effector nucleases (TALENs) has led to significant advances in diverse areas of science and medicine. In this review, we provide a broad overview of the development of TALENs and the use of this technology in basic science, biotechnology, and biomedical applications. This includes the discovery of DNA recognition by TALEs, engineering new TALE proteins to diverse targets, general advances in nuclea...

  7. Biotechnology for Chemical Production: Challenges and Opportunities.

    Science.gov (United States)

    Burk, Mark J; Van Dien, Stephen

    2016-03-01

    Biotechnology offers a new sustainable approach to manufacturing chemicals, enabling the replacement of petroleum-based raw materials with renewable biobased feedstocks, thereby reducing greenhouse gas (GHG) emissions, toxic byproducts, and the safety risks associated with traditional petrochemical processing. Development of such bioprocesses is enabled by recent advances in genomics, molecular biology, and systems biology, and will continue to accelerate as access to these tools becomes faster and cheaper.

  8. MIPs as Tools in Environmental Biotechnology.

    Science.gov (United States)

    Mattiasson, Bo

    2015-01-01

    Molecular imprints are potentially fantastic constructions. They are selective, robust, and nonbiodegradable if produced from stable polymers. A range of different applications has been presented, everything from separation of enantiomers, via adsorbents for sample preparation before analysis to applications in wastewater treatment. This chapter deals with molecularly imprinted polymers (MIPs) as tools in environmental biotechnology, a field that has the potential to become very important in the future.

  9. Improved molecular tools for sugar cane biotechnology.

    Science.gov (United States)

    Kinkema, Mark; Geijskes, Jason; Delucca, Paulo; Palupe, Anthony; Shand, Kylie; Coleman, Heather D; Brinin, Anthony; Williams, Brett; Sainz, Manuel; Dale, James L

    2014-03-01

    Sugar cane is a major source of food and fuel worldwide. Biotechnology has the potential to improve economically-important traits in sugar cane as well as diversify sugar cane beyond traditional applications such as sucrose production. High levels of transgene expression are key to the success of improving crops through biotechnology. Here we describe new molecular tools that both expand and improve gene expression capabilities in sugar cane. We have identified promoters that can be used to drive high levels of gene expression in the leaf and stem of transgenic sugar cane. One of these promoters, derived from the Cestrum yellow leaf curling virus, drives levels of constitutive transgene expression that are significantly higher than those achieved by the historical benchmark maize polyubiquitin-1 (Zm-Ubi1) promoter. A second promoter, the maize phosphonenolpyruvate carboxylate promoter, was found to be a strong, leaf-preferred promoter that enables levels of expression comparable to Zm-Ubi1 in this organ. Transgene expression was increased approximately 50-fold by gene modification, which included optimising the codon usage of the coding sequence to better suit sugar cane. We also describe a novel dual transcriptional enhancer that increased gene expression from different promoters, boosting expression from Zm-Ubi1 over eightfold. These molecular tools will be extremely valuable for the improvement of sugar cane through biotechnology.

  10. Digital and analog gene circuits for biotechnology.

    Science.gov (United States)

    Roquet, Nathaniel; Lu, Timothy K

    2014-05-01

    Biotechnology offers the promise of valuable chemical production via microbial processing of renewable and inexpensive substrates. Thus far, static metabolic engineering strategies have enabled this field to advance industrial applications. However, the industrial scaling of statically engineered microbes inevitably creates inefficiencies due to variable conditions present in large-scale microbial cultures. Synthetic gene circuits that dynamically sense and regulate different molecules can resolve this issue by enabling cells to continuously adapt to variable conditions. These circuits also have the potential to enable next-generation production programs capable of autonomous transitioning between steps in a bioprocess. Here, we review the design and application of two main classes of dynamic gene circuits, digital and analog, for biotechnology. Within the context of these classes, we also discuss the potential benefits of digital-analog interconversion, memory, and multi-signal integration. Though synthetic gene circuits have largely been applied for cellular computation to date, we envision that utilizing them in biotechnology will enhance the efficiency and scope of biochemical production with living cells.

  11. New biotechnological procedures in swine reproduction

    Directory of Open Access Journals (Sweden)

    Petrujkić Tihomir

    2002-01-01

    Full Text Available New biotechnological procedures and the use of hormones in swine breeding are aimed at increasing the number of piglets in the litter. In small herds and groups, selected sows with 16 mammary complexes (tits can yield up to 32 piglets, or porkers, per year per sow. In order to achieve such reproduction results, special, individual stalls for sow deliveries are used, in addition to biotechnological methods, with a warm core and floor heating, phased diet and clean facilities. The ovulation value in swine is determined by their genetic and paragenetic effects, and it is often provoked and increased with injections and preparations for superovulation. However, the results vary, since any administration of hormone injecions can reduce the reproductive cycle, shorten the duration of estrus, or disrupt the work of ovaries and create cystic follicles. The use of follicle-stimulating hormones in quantities up to 1000 IU per animal for the induction and synchronization of estrus has become customary for sows and gilts, as well as the use of prostaglandins, the use of GnRH for increasing ovulation in swine and increasing the number of follicles >4 mm in diameter in the implementation of new biotechnologies in swine breeding, increases the number of ovulations and fertility in swine. In this way, reproduction is raised to the highest possible level, and artificial insemination of sows has 12 separate rules which enable better and more successful artificial insemination of sows.

  12. Status of coal biotechnology in Pakistan

    Energy Technology Data Exchange (ETDEWEB)

    M. Afzal Ghauri; M.A. Anwar; N. Akhtar; R. Haider; A. Tawab [National Institute for Biotechnology and Genetic Engineering, Faisalabad (Pakistan)

    2009-07-01

    Pakistan is endued with 185 billion tons colossal reserves of coal, but only 7.89 % of the country total energy requirements are met by coal. Most of the Pakistani coal reserves are sub-bituminous or lignitic in nature and contain 3-12 % sulphur. Existence of sulphur compounds in coal limits its industrial application due to environmental as well as technical problems. However, coal biotechnology can emerge as panacea for upgrading the huge reserves of coal in Pakistan. In general, coal biotechnology refers to biodesulphurization, biosolubilization and biogasification of coal. NIBGE has long term interests in the field of coal bioprocessing for tapping prime resources of indigenous coal. In NIBGE, lab scale experiments for coal biodesulphurization led to 90% efficiency in sulphur removal. Heap leaching was also carried out at the level of 10 and 20 tons coal heaps with 60% sulphur removal efficiency. Furthermore, a prototype of 300 tons coal heap was set up with a local cement industry and 75% microbial desulphurization was achieved. The league of indigenously isolated chemolithotrophic bacteria was involved in coal desulphurization. On the other side, for making the best use of 175 billion tons of low rank coal reserves, coal biosolubilization and subsequent biogasification is being projected. Consequently, beneficiated coal through biotechnology is supposed to contribute in energy mix of Pakistan for providing electricity requirements of the country and saving huge oil import bills.

  13. Biotechnology of temperate fruit trees and grapevines.

    Science.gov (United States)

    Laimer, Margit; Mendonça, Duarte; Maghuly, Fatemeh; Marzban, Gorji; Leopold, Stephan; Khan, Mahmood; Balla, Ildiko; Katinger, Hermann

    2005-01-01

    Challenges concerning fruit trees and grapevines as long lived woody perennial crops require adapted biotechnological approaches, if solutions are to be found within a reasonable time frame. These challenges are represented by the need for correct identification of genetic resources, with the foreseen use either in conservation or in breeding programmes. Molecular markers provide most accurate information and will be the major solution for questions about plant breeders rights. Providing healthy planting material and rapid detection of newly introduced pathogens by reliable methods involving serological and molecular biological tools will be a future challenge of increases importance, given the fact that plant material travels freely in the entire European Union. But also new breeding goals and transgenic solutions are part of the biotechnological benefits, e.g. resistance against biotic and abiotic stress factors, modified growth habits, modified nutritional properties and altered processing and storage qualities. The successful characterization of transgenic grapevines and stone fruit trees carrying genes of viral origin in different vectors constructed under ecological consideration, will be presented. Beyond technical feasibility, efficiency of resistance, environmental safety and Intellectual Property Rights, also public acceptance needs consideration and has been addressed in a specific project. The molecular determination of internal quality parameters of food can also be addressed by the use of biotechnological tools. Patient independent detection tools for apple allergens have been developed and should allow to compare fruits from different production systems, sites, and genotypes for their content of health threatening compounds.

  14. Methods in industrial biotechnology for chemical engineers

    CERN Document Server

    Kandasamy, W B Vasantha

    2008-01-01

    In keeping with the definition that biotechnology is really no more than a name given to a set of techniques and processes, the authors apply some set of fuzzy techniques to chemical industry problems such as finding the proper proportion of raw mix to control pollution, to study flow rates, to find out the better quality of products. We use fuzzy control theory, fuzzy neural networks, fuzzy relational equations, genetic algorithms to these problems for solutions. When the solution to the problem can have certain concepts or attributes as indeterminate, the only model that can tackle such a situation is the neutrosophic model. The authors have also used these models in this book to study the use of biotechnology in chemical industries. This book has six chapters. First chapter gives a brief description of biotechnology. Second chapter deals will proper proportion of mix of raw materials in cement industries to minimize pollution using fuzzy control theory. Chapter three gives the method of determination of te...

  15. Independent Biotechnology: The Innovation-Regulation Dilemma

    Energy Technology Data Exchange (ETDEWEB)

    Althouse, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Prosnitz, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Velsko, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-11-03

    The Center for Global Security Research at Lawrence Livermore National Laboratory convened a workshop on August 19, 2016 to consider “Independent Biotechnology: The Innovation-­Regulation Dilemma”. The topic was motivated by the observation that non-­government funded biotechnology research and development activities have grown and diversified tremendously over the past decade. This sector encompasses a broad range of actors and activities: individuals with private laboratories, community “hackerspaces,” biotechnology incubators, and individual startups. Motivations and aspirations are diverse and include such things as personal curiosity, community education, the invention of new products or services, and even the realization of certain economic, political, or social goals. One driving force is the “democratization” of ever more powerful biological technologies, allowing individual citizens and groups access to capabilities that have traditionally only been available to researchers in universities, research institutes, national laboratories, and large commercial concerns. Another is the rise of alternative financing mechanisms such as “crowdsourcing,” which ostensibly provide greater freedom to innovate, and greater public visibility, but entail looser management oversight and transparency.

  16. International Marine Biotechnology Culture Collection (IMBCC)

    Energy Technology Data Exchange (ETDEWEB)

    Zaborsky, O.R.; Baker, K. [Univ. of Hawaii at Manoa, Honolulu, HI (United States)

    1996-10-01

    The objective of this project is to establish a premier culture collection of tropical marine microorganisms able to generate hydrogen from water or organic substances. Both eukaryotic and prokaryotic microorganisms will serve as the biological reservoir or {open_quotes}library{close_quotes} for other DOE Hydrogen Program contractors, the biohydrogen research community and industry. This project consists of several tasks: (a) transfer of the Mitsui-Miami strains to Hawaii`s International Marine Biotechnology Culture Collection (IMBCC) housed at the Hawaii Natural Energy Institute (HNEI); (b) maintain and distribute Mitsui-Miami strains; (c) characterize key strains by traditional and advanced biotechnological techniques; (d) expand Hawaii`s IMBCC; and (e) establish and operate an information resource (database). The project was initiated only late in the summer of 1995 but progress has been made on all tasks. Of the 161 cyanobacterial strains imported, 147 survived storage and importation and 145 are viable. with most exhibiting growth. Of the 406 strains of other photosynthetic bacteria imported, 392 survived storage and importation and 353 are viable, with many exhibiting growth. This project is linked to cooperative efforts being supported by the Japanese Ministry of International Trade and Industry (MITI) through its Marine Biotechnology Institute (MBI) and Research Institute of Innovative Technology for the Earth (RITE).

  17. 农业生物技术相关课程科研型教学模式的探索与实践%An Exploration on Research-based Teaching Model of Agricultural Biotechnological Courses: A Case Study in Northwest A&F University

    Institute of Scientific and Technical Information of China (English)

    李春莲; 杜世平; 陈耀锋

    2012-01-01

    Research-based teaching is not only an inevitable teaching trend in research-based university, but an effective approach of cultivating college students. Based on the teaching practices in Northwest A&F University and taking the agTicultural biotechnological courses as research objective, a new research-based teaching model, which takes college students as main body and teachers as a leading body, incorporates basic academic research elements into the teaching in order to cultivate the students' scientific spirit and innovative abilities of creative and critical thinking and fluent and elaborative reasoning. Furthermore, an operational mechanism of research-based teaching model including the textbook choice, theory teaching, course discussion, and course practice and course evaluation is discussed in details.%科研型教学模式既是研究型大学教学发展的必然趋势,也是培养当代大学生的有效途径。以农业生物技术相关课程为研究对象,结合西北农林科技大学农学院的教学实践,提出了科研型教学模式,即以学生为主体,教师为主导,通过将科学研究的基本要素引入到教学当中,以培养学生的科学精神、创造性思维和创新能力为目标。在此基础上,分别从教材选用、课程理论、课堂讨论、课程实践及课程考核等五个方面阐述了科研型教学模式的运行机理。

  18. ISS Biotechnology Facility - Overview of Analytical Tools for Cellular Biotechnology Investigations

    Science.gov (United States)

    Jeevarajan, A. S.; Towe, B. C.; Anderson, M. M.; Gonda, S. R.; Pellis, N. R.

    2001-01-01

    The ISS Biotechnology Facility (BTF) platform provides scientists with a unique opportunity to carry out diverse experiments in a microgravity environment for an extended period of time. Although considerable progress has been made in preserving cells on the ISS for long periods of time for later return to Earth, future biotechnology experiments would desirably monitor, process, and analyze cells in a timely way on-orbit. One aspect of our work has been directed towards developing biochemical sensors for pH, glucose, oxygen, and carbon dioxide for perfused bioreactor system developed at Johnson Space Center. Another aspect is the examination and identification of new and advanced commercial biotechnologies that may have applications to on-orbit experiments.

  19. New developments in crop plant biotechnology and their possible implications for food product safety : literature study under commission of the foundation 'Consument and biotechnologie'

    NARCIS (Netherlands)

    Kleter, G.A.

    2000-01-01

    This study reports recent developments in the application of biotechnology in agriculture in order to assess whether current food safety evaluations strategies are adequate in view of these new and presumably more far reaching developments. Trends are observed that may require additional regulatory

  20. Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.

    Science.gov (United States)

    Goodner, B; Hinkle, G; Gattung, S; Miller, N; Blanchard, M; Qurollo, B; Goldman, B S; Cao, Y; Askenazi, M; Halling, C; Mullin, L; Houmiel, K; Gordon, J; Vaudin, M; Iartchouk, O; Epp, A; Liu, F; Wollam, C; Allinger, M; Doughty, D; Scott, C; Lappas, C; Markelz, B; Flanagan, C; Crowell, C; Gurson, J; Lomo, C; Sear, C; Strub, G; Cielo, C; Slater, S

    2001-12-14

    Agrobacterium tumefaciens is a plant pathogen capable of transferring a defined segment of DNA to a host plant, generating a gall tumor. Replacing the transferred tumor-inducing genes with exogenous DNA allows the introduction of any desired gene into the plant. Thus, A. tumefaciens has been critical for the development of modern plant genetics and agricultural biotechnology. Here we describe the genome of A. tumefaciens strain C58, which has an unusual structure consisting of one circular and one linear chromosome. We discuss genome architecture and evolution and additional genes potentially involved in virulence and metabolic parasitism of host plants.

  1. The potential of using biotechnology to improve cassava: a review

    OpenAIRE

    Chavarriaga-Aguirre, Paul; Brand, Alejandro; Medina, Adriana; Prías, Mónica; Escobar, Roosevelt; Martinez, Juan; Díaz, Paula; LÓPEZ, CAMILO; Roca, Willy M; Tohme, Joe

    2016-01-01

    The importance of cassava as the fourth largest source of calories in the world requires that contributions of biotechnology to improving this crop, advances and current challenges, be periodically reviewed. Plant biotechnology offers a wide range of opportunities that can help cassava become a better crop for a constantly changing world. We therefore review the state of knowledge on the current use of biotechnology applied to cassava cultivars and its implications for breeding the crop into ...

  2. The evolution of the biotechnology industry in Germany.

    Science.gov (United States)

    Müller, Christian

    2002-07-01

    In the past five years, the climate for commercial biotechnology in Germany has improved significantly and has resulted in an increase in the number of biotechnology companies. On examination of the underlying factors of the evolution of the biotechnology industry in Germany, and against the background of the current situation, it is predicted that many German biotech companies will have to change their business models to focus on product development rather than on platform technologies.

  3. PUBLIC PERCEPTIONS OF BIOTECHNOLOGY AND ACCEPTANCE OF GENETICALLY MODIFIED FOOD

    OpenAIRE

    Hossain, Ferdaus; Onyango, Benjamin M.; Schilling, Brian J.; Hallman, William K.

    2003-01-01

    Public debate on biotechnology is embroiled in controversy over the risks and benefits associated with this emerging technology. Using data from a national survey, this study analyzes public acceptance of biotechnology in food production. Empirical results suggest that while there is general optimism about biotechnology and support for its use in plants, public approval of its use in animals is perhaps more limited. Younger and more-educated individuals are generally more supportive of biotec...

  4. The Carolina conference on marine biotechnology: Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Frankenberg, D.

    1985-01-01

    This report summarizes proceedings of a Carolina Conference on Marine Biotechnology held March 24-26, 1985, at the University of North Carolina at Chapel Hill. This report consists of the responders' summary of each topic discussed. The topics presented were General Prospects for Marine Biotechnology, Bioactive Substances from Marine Organisms, Fundamental Processes in Marine Organisms as Guides for Biotechnology Development, Genetic Manipulation of Potential Use to Mariculture, Organisms Interactions with Marine Surfaces: Marine Glues, and Biomolecular Engineering Materials Applications.

  5. Benefits of new tools in biotechnology to developing countries in south Asia: a perspective from UNESCO.

    Science.gov (United States)

    Fahmi, Ahmed

    2011-12-20

    South Asia, once considered as a laggard, has grown at about 6% on average over the past two decades and the current growth outlook is much brighter. However, this growth is not always well distributed and the challenges of institutionalising policies and mechanisms to ensure inclusive growth are now being seriously considered by these countries governments. The targets set by south Asian countries are primarily based on the investments in infrastructural sector with an objective to generate educated and skilled human resources. The other most important inclusive growth area is the core public services; Agriculture, Health, and Energy, which are increasingly becoming technology driven. Biotechnology has been increasingly seen now to be an area of technology that holds the greatest new potential to address problems arising from low productivity, overburdened health systems, high-cost unsustainable energy supplies and the need for developing new materials for industrial and environmental applications. This article attempts to highlight perspectives on some of the emerging areas of biotechnology that have good potential for economic development in the context of south Asia, as well as discuss briefly some of UNESCO's initiatives in biotechnology for that region.

  6. Biotechnology as the engine for the Knowledge-Based Bio-Economy.

    Science.gov (United States)

    Aguilar, Alfredo; Bochereau, Laurent; Matthiessen, Line

    2010-01-01

    The European Commission has defined the Knowledge-Based Bio-Economy (KBBE) as the process of transforming life science knowledge into new, sustainable, eco-efficient and competitive products. The term "Bio-Economy" encompasses all industries and economic sectors that produce, manage and otherwise exploit biological resources and related services. Over the last decades biotechnologies have led to innovations in many agricultural, industrial, medical sectors and societal activities. Biotechnology will continue to be a major contributor to the Bio-Economy, playing an essential role in support of economic growth, employment, energy supply and a new generation of bio-products, and to maintain the standard of living. The paper reviews some of the main biotechnology-related research activities at European level. Beyond the 7th Framework Program for Research and Technological Development (FP7), several initiatives have been launched to better integrate FP7 with European national research activities, promote public-private partnerships and create better market and regulatory environments for stimulating innovation.

  7. Waste valorization by biotechnological conversion into added value products.

    Science.gov (United States)

    Liguori, Rossana; Amore, Antonella; Faraco, Vincenza

    2013-07-01

    Fossil fuel reserves depletion, global warming, unrelenting population growth, and costly and problematic waste recycling call for renewable resources of energy and consumer products. As an alternative to the 100 % oil economy, production processes based on biomass can be developed. Huge amounts of lignocellulosic wastes are yearly produced all around the world. They include agricultural residues, food farming wastes, "green-grocer's wastes," tree pruning residues, and organic and paper fraction of urban solid wastes. The common ways currently adopted for disposal of these wastes present environmental and economic disadvantages. As an alternative, processes for adding value to wastes producing high added products should be developed, that is the upgrading concept: adding value to wastes by production of a product with desired reproducible properties, having economic and ecological advantages. A wide range of high added value products, such as enzymes, biofuels, organic acids, biopolymers, bioelectricity, and molecules for food and pharmaceutical industries, can be obtained by upgrading solid wastes. The most recent advancements of their production by biotechnological processes are overviewed in this manuscript.

  8. [Trends of microalgal biotechnology: a view from bibliometrics].

    Science.gov (United States)

    Yang, Xiaoqiu; Wu, Yinsong; Yan, Jinding; Song, Haigang; Fan, Jianhua; Li, Yuanguang

    2015-10-01

    Microalgae is a single-cell organism with the characteristics of high light energy utilization rate, fast growth rate, high-value bioactive components and high energy material content. Therefore, microalgae has broad application prospects in food, feed, bioenergy, carbon sequestration, wastewater treatment and other fields. In this article, the microalgae biotechnology development in recent years were fully consulted, through analysis from the literature and patent. The progress of microalgal biotechnology at home and abroad is compared and discussed. Furthermore, the project layout, important achievements and development bottlenecks of microalgae biotechnology in our country were also summarized. At last, future development directions of microalgae biotechnology were discussed.

  9. The biotechnology innovation machine: a source of intelligent biopharmaceuticals for the pharma industry--mapping biotechnology's success.

    Science.gov (United States)

    Evens, R P; Kaitin, K I

    2014-05-01

    The marriage of biotechnology and the pharmaceutical industry (pharma) is predicated on an evolution in technology and product innovation. It has come as a result of advances in both the science and the business practices of the biotechnology sector in the past 30 years. Biotechnology products can be thought of as "intelligent pharmaceuticals," in that they often provide novel mechanisms of action, new approaches to disease control, higher clinical success rates, improved patient care, extended patent protection, and a significant likelihood of reimbursement. Although the first biotechnology product, insulin, was approved just 32 years ago in 1982, today there are more than 200 biotechnology products commercially available. Research has expanded to include more than 900 biotechnology products in clinical trials. Pharma is substantially engaged in both the clinical development of these products and their commercialization.

  10. Biotechnology Protein Expression and Purification Facility

    Science.gov (United States)

    2003-01-01

    The purpose of the Project Scientist Core Facility is to provide purified proteins, both recombinant and natural, to the Biotechnology Science Team Project Scientists and the NRA-Structural Biology Test Investigators. Having a core facility for this purpose obviates the need for each scientist to develop the necessary expertise and equipment for molecular biology, protein expression, and protein purification. Because of this, they are able to focus their energies as well as their funding on the crystallization and structure determination of their target proteins.

  11. Life sciences and biotechnology in China

    OpenAIRE

    Chen, Zhu; Wang, Hong-Guang; Wen, Zhao-Jun; Wang, Yihuang

    2007-01-01

    Life science and biotechnology have become a top priority in research and development in many countries as the world marches into the new century. China as a developing country with a 1.3 billion population and booming economy is actively meeting the challenge of a new era in this area of research. Owing to support from the government and the scientific community, and reform to improve the infrastructure, recent years have witnessed a rapid progress in some important fields of life science an...

  12. Chrysanthemum biotechnology: discoveries from the recent literature

    Directory of Open Access Journals (Sweden)

    Teixeira da Silva Jaime A.

    2014-12-01

    Full Text Available The in vitro propagation of chrysanthemum (Chrysanthemum × grandiflorum (Ramat. Kitam., one of the world’s most important ornamentals, is a very well-studied topic and shows numerous strides each year. This mini-review condenses the knowledge that has been published on chrysanthemum biotechnology, especially in vitro culture in the wider plant science literature. In 2013 and 2014, important strides were made in molecular breeding, particularly anti-viral strategies, including through transgenics, and our understanding of flower genetics and flowering regulation.

  13. New developments in Biotechnology-an overview

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    人类运用生物技术已经几千年了.直到上个世纪,发酵方法生产啤酒、白酒、面包、酱油以及其它食品都是在农产品领域的主要应用.自从50年前DNA和RNA结构和作用被揭示以来,一场生物技术的革命便产生了,并导致了两项关键技术的发展:1)通过基因技术进行遣传因素的修改;2)新型快速多样分析工具;最新的发展都基于遗传学.这篇文章我将探讨以下问题:遗传因子修改的进展和公众认可的争论;基因学技术在农产品领域的应用;我的TNO研究所与中国伙伴联合的生物技术项目的例子;谷物科技方面的生物技术.%Mankind applies biotechnology already for thousands of years. Until the last century, fermentation processes for producing beer, wine, bread, soy sauces and other food products were the main application in the agri- food area. The elucidation of the structure and role of DNA and RNA in living organisms since the past 50 years has created a revolution in biotechnology, resulting in two key technological developments: 1) Genetic modification by gene technology 2) New rapid and multiple analytical tools; the latest developments being based on genomics. In this presentation I will discuss: - progress in genetic modification and the issue of public acceptance - application of genomic based technologies in the agri- food field - examples of joint biotechnology projects of my TNO institute with partners in China - biotechnology in cereal science and technology

  14. Biotechnologies and biomimetics for civil engineering

    CERN Document Server

    Labrincha, J; Diamanti, M; Yu, C-P; Lee, H

    2015-01-01

    Putting forward an innovative approach to solving current technological problems faced by human society, this book encompasses a holistic way of perceiving the potential of natural systems. Nature has developed several materials and processes which both maintain an optimal performance and are also totally biodegradable, properties which can be used in civil engineering. Delivering the latest research findings to building industry professionals and other practitioners, as well as containing information useful to the public, ‘Biotechnologies and Biomimetics for Civil Engineering’ serves as an important tool to tackle the challenges of a more sustainable construction industry and the future of buildings.

  15. Downstream processing in the biotechnology industry.

    Science.gov (United States)

    Kalyanpur, Manohar

    2002-09-01

    The biotechnology industry today employs recombinant bacteria, mammalian cells, and transgenic animals for the production of high-value therapeutic proteins. This article reviews the techniques employed in this industry for the recovery of these products. The methods reviewed extend from the centrifugation and membrane filtration for the initial clarification of crude culture media to the final purification of the products by a variety of membrane-based and chromatographic methods. The subject of process validation including validation of the removal of bacterial and viral contaminants from the final products is also discussed with special reference to the latest regulatory guidelines.

  16. Biotechnological aspects of plum pox virus.

    Science.gov (United States)

    López-Moya, J J; Fernández-Fernández, M R; Cambra, M; García, J A

    2000-01-21

    Plum pox potyvirus (PPV), the causal agent of a devastating disease that affects stone fruit trees, is becoming a target of intense studies intended both to fight against viral infection and to develop practical applications based on the current knowledge of potyvirus molecular biology. This review focuses on biotechnological aspects related to PPV, such as novel diagnostic techniques that facilitate detection and typing of virus isolates, strategies to implement pathogen-derived resistance through plant transformation, the potential use of genetic elements derived from the virus, and the recent development of PPV-based expression vectors.

  17. Are echinoderms of interest to biotechnology?

    Science.gov (United States)

    Petzelt, C

    2005-01-01

    The huge potential of echinoderms as a so far fairly untapped source of bioactive molecules is described. Examples are presented that show the usefulness of echinoderm-derived molecules for therapeutic application in selected fields of cancer research, in the control of bacterial growth as substances with new antibiotic properties, and finally in the context of technical applications such as antifouling substances. The molecules described here are but the mere beginning of a commercial exploitation of echinoderms and may incite a deeper involvement of biotechnology-oriented research in this material.

  18. Energy-based models for environmental biotechnology.

    Science.gov (United States)

    Rodríguez, Jorge; Lema, Juan M; Kleerebezem, Robbert

    2008-07-01

    Environmental biotechnology is evolving. Current process objectives include the production of chemicals and/or energy carriers (biofuels) in addition to the traditional objective of removing pollutants from waste. To maximise product yields and minimise biomass production, future processes will rely on anaerobic microbial communities. Anaerobic processes are characterised by small Gibbs energy changes in the reactions catalysed, and this provides clear thermodynamic process boundaries. Here, a Gibbs-energy-based methodology is proposed for mathematical modelling of energy-limited anaerobic ecosystems. This methodology provides a basis for the description of microbial activities as a function of environmental factors, which will allow enhanced catalysis of specific reactions of interest for process development.

  19. Biotechnological Processes in Microbial Amylase Production

    Directory of Open Access Journals (Sweden)

    Subash C. B. Gopinath

    2017-01-01

    Full Text Available Amylase is an important and indispensable enzyme that plays a pivotal role in the field of biotechnology. It is produced mainly from microbial sources and is used in many industries. Industrial sectors with top-down and bottom-up approaches are currently focusing on improving microbial amylase production levels by implementing bioengineering technologies. The further support of energy consumption studies, such as those on thermodynamics, pinch technology, and environment-friendly technologies, has hastened the large-scale production of the enzyme. Herein, the importance of microbial (bacteria and fungi amylase is discussed along with its production methods from the laboratory to industrial scales.

  20. Biotechnology Education as Social and Cultural Production/Reproduction of the Biotechnology Community

    Science.gov (United States)

    Andrée, Maria

    2014-01-01

    This paper is a commentary to a paper by Anne Solli, Frank Bach and Björn Åkerman on how students at a technical university learn to argue as biotechnologists. Solli and her colleagues report from an ethnographic study performed during the first semester of a 5-year program in biotechnology at a technical university in Sweden. Their study…

  1. Biotechnology education as social and cultural production/reproduction of the biotechnology community

    Science.gov (United States)

    Andrée, Maria

    2014-03-01

    This paper is a commentary to a paper by Anne Solli, Frank Bach and Björn Åkerman on how students at a technical university learn to argue as biotechnologists. Solli and her colleagues report from an ethnographic study performed during the first semester of a 5-year program in biotechnology at a technical university in Sweden. Their study demonstrates how students begin to acquire `the right way' of approaching the controversial issue of producing and consuming genetically modified organisms. In my response I discuss the ethnographic account of this particular educational practice in terms of social and cultural production/reproduction of a biotechnology community and how the participants (students and teaching professors) deal with the dialectic of individual and collective transformation. In the perspective of the biotechnology community, the work done by the teaching professor becomes a way of ensuring the future of the biotechnology community in terms of what values and objectives are held highly in the community of practice.

  2. Ex-ante evaluation of biotechnology innovations: the case of folate biofortified rice in China.

    Science.gov (United States)

    De Steur, Hans; Blancquaert, Dieter; Gellynck, Xavier; Lambert, Willy; Van Der Straeten, Dominique

    2012-12-01

    In order to valorize novel biotechnology innovations, there is a need to evaluate ex-ante their market potential. A case in point is biofortification, i.e. the enhancement of the micronutrient content of staple crops through conventional or genetic breeding techniques. In a recent article in Nature Biotechnology, for example, De Steur et al. (2010) demonstrated the large potential consumer health benefits of folate biofortified rice as a means to reduce folate deficiency and Neural-Tube Defects. By focusing on a Chinese high-risk region of Neural-Tube Defects, the current study defines the potential cost-effectiveness of this genetically modified crop where the need to improve folate intake levels is highest. Building on the Disability-Adjusted Life Years (DALY) approach, both the potential health impacts and costs of its implementation are measured and benchmarked against similar innovations. The results show that this transgenic crop could be a highly cost-effective product innovation (US$ 120.34 - US$ 40.1 per DALY saved) to alleviate the large health burden of folate deficiency and reduce the prevalence of neural-tube birth defects. When compared with other biofortified crops and target regions, folate biofortified rice in China has a relatively high health impact and moderate cost-effectiveness. This research further supports the need for, and importance of ex-ante evaluation studies in order to adequately market and, thus, valorize biotechnology innovations. Although the cost-effectiveness analysis enables to illustrate the market potential of innovative agricultural biotechnology research, further research is required to address policy issues on transgenic biofortification, such as biosafety regulatory requirements.

  3. Global unbalance in seaweed production, research effort and biotechnology markets.

    Science.gov (United States)

    Mazarrasa, Inés; Olsen, Ylva S; Mayol, Eva; Marbà, Núria; Duarte, Carlos M

    2014-01-01

    Exploitation of the world's oceans is rapidly growing as evidenced by a booming patent market of marine products including seaweed, a resource that is easily accessible without sophisticated bioprospecting technology and that has a high level of domestication globally. The investment in research effort on seaweed aquaculture has recently been identified to be the main force for the development of a biotechnology market of seaweed-derived products and is a more important driver than the capacity of seaweed production. Here, we examined seaweed patent registrations between 1980 and 2009 to assess the growth rate of seaweed biotechnology, its geographic distribution and the types of applications patented. We compare this growth with scientific investment in seaweed aquaculture and with the market of seaweed production. We found that both the seaweed patenting market and the rate of scientific publications are rapidly growing (11% and 16.8% per year respectively) since 1990. The patent market is highly geographically skewed (95% of all registrations belonging to ten countries and the top two holding 65% of the total) compared to the distribution of scientific output among countries (60% of all scientific publications belonging to ten countries and the top two countries holding a 21%), but more homogeneously distributed than the production market (with a 99.8% belonging to the top ten countries, and a 71% to the top two). Food industry was the dominant application for both the patent registrations (37.7%) and the scientific publications (21%) followed in both cases by agriculture and aquaculture applications. This result is consistent with the seaweed taxa most represented. Kelp, which was the target taxa for 47% of the patent registrations, is a traditional ingredient in Asian food and Gracilaria and Ulva, which were the focus of 15% and 13% of the scientific publications respectively, that are also used in more sophisticated applications such as cosmetics, chemical

  4. Biotechnology for Sustainable Crop Production and Protection: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    T. M. Manjunath

    2010-07-01

    Full Text Available In 2009, transgenic crops were grown on 134 million hectares in 25 countries, including India, in six continents by about 14million farmers, marking an 80-fold increase in the area since their first commercialization on 1.7 m ha in the USA and fiveother countries in 1996. The dominant transgenic traits were herbicide tolerance and insect resistance, deployed either alone orboth stacked in the same plant. A recent survey of the global impact of biotech crops estimated that in 2008 alone, the totalcrop production gain globally for the 4 principal biotech crops - maize, soybean, cotton and canola - was 29.6 million metrictons while the net economic benefit to the biotech farmers was US$ 9.2 billion. The cumulative benefits for the period 1996-2008 were yield gains of 167 million tons and economic returns of US$ 51.9 billion. In India, the area planted with Bt-cottonincreased significantly from year to year since its introduction in 2002 and reached 8.4 million hectares in 2009. The overallbenefits from Bt-cotton included an yield increase of up to 63% due to effective control of bollworms, pesticide reduction by50%, net profit to farmers up to Rs.10,000/hectare and turned India from an importer to a major exporter of cotton. Theseindicate that biotechnology has made significant contributions to higher productivity, lower costs of production and increasedeconomic benefits and that it has enormous potential for the future with new traits, events and crops. Over 60 countries,including India, are engaged in research on about 55 crop species to incorporate transgenes to bestow various traits such asresistance to pests, diseases or herbicides; tolerance to environmental stresses like drought, cold or salinity; enhanced cropyields, nutrition or shelf-life, etc. However, unreasonable opposition to biotechnology and undue delays in regulatoryapprovals are some of the major challenges that need to be addressed so as to make full use of this technology which

  5. Why are some proteins allergenic? Implications for biotechnology.

    Science.gov (United States)

    Lehrer, S B; Horner, W E; Reese, G

    1996-07-01

    In recent years, a number of agricultural crops have been developed with recombinant DNA technology. Because the transferred genes code for proteins that are ordinarily not present in these particular foods, there is concern about the potential allergenicity of these new crop varieties. Foods contain many proteins; however, only a small fraction are allergens. Although the structural properties of proteins that cause allergic reactions have not been characterized completely, known food allergens in general have molecular weights between 10 and 70 kDa, stimulate the immune response (induce the production of allergen-specific IgE), and are stable molecules that are resistant to processing, cooking, and digestion. Although any type of food is potentially allergenic, the majority of food allergies are caused by a small group of foods (cows' milk, nuts, legumes, eggs, seafood). Cross-reactivities occur within a given food group and between foods and seemingly unrelated proteins. Even though most transgenic foods are considered safe, biotechnological manipulation can affect crop allergenicity. The safety evaluation of transgenic foods is relatively easy when the allergenicity of the gene sources are known. The recombinant food can be assayed using traditional in vitro inhibition assays. Recently, reduced allergen content of biotechnologically altered rice was shown. In contrast, increased allergenicity was demonstrated in transgenic soybeans after a methionine- and cystine-rich protein from Brazil nuts, identified as a major Brazil nut allergen, was expressed in soybean to increase its content of sulfur-rich amino acids. The most difficult issue regarding transgenic food allergenicity is the effect of transfer of proteins of unknown allergenicity. The challenge is to determine whether these proteins are allergenic as there is no generally accepted, established, definitive procedure to define or predict a protein's allergenicity. Comparing the structures of the

  6. Alternative Agriculture

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Will the popularization of bioenergy, a new source for powering China, trigger another agricultural revolution? Skyrocketing energy prices, especially the oil shock in the first half of 2005, are pushing China to seek more substitutes for gasoline. A number of cities are turning to ethanol-blended gas made from com. Starting this month, the sale of regular gasoline will be brought to an end in nine of China's

  7. Halophiles, coming stars for industrial biotechnology.

    Science.gov (United States)

    Yin, Jin; Chen, Jin-Chun; Wu, Qiong; Chen, Guo-Qiang

    2015-11-15

    Industrial biotechnology aims to produce chemicals, materials and biofuels to ease the challenges of shortage on petroleum. However, due to the disadvantages of bioprocesses including energy consuming sterilization, high fresh water consumption, discontinuous fermentation to avoid microbial contamination, highly expensive stainless steel fermentation facilities and competing substrates for human consumption, industrial biotechnology is less competitive compared with chemical processes. Recently, halophiles have shown promises to overcome these shortcomings. Due to their unique halophilic properties, some halophiles are able to grow in high pH and high NaCl containing medium under higher temperature, allowing fermentation processes to run contamination free under unsterile conditions and continuous way. At the same time, genetic manipulation methods have been developed for halophiles. So far, halophiles have been used to produce bioplastics polyhydroxyalkanoates (PHA), ectoines, enzymes, and bio-surfactants. Increasing effects have been made to develop halophiles into a low cost platform for bioprocessing with advantages of low energy, less fresh water consumption, low fixed capital investment, and continuous production.

  8. Biotechnology Applications of Tethered Lipid Bilayer Membranes

    Directory of Open Access Journals (Sweden)

    Joshua A. Jackman

    2012-12-01

    Full Text Available The importance of cell membranes in biological systems has prompted the development of model membrane platforms that recapitulate fundamental aspects of membrane biology, especially the lipid bilayer environment. Tethered lipid bilayers represent one of the most promising classes of model membranes and are based on the immobilization of a planar lipid bilayer on a solid support that enables characterization by a wide range of surface-sensitive analytical techniques. Moreover, as the result of molecular engineering inspired by biology, tethered bilayers are increasingly able to mimic fundamental properties of natural cell membranes, including fluidity, electrical sealing and hosting transmembrane proteins. At the same time, new methods have been employed to improve the durability of tethered bilayers, with shelf-lives now reaching the order of weeks and months. Taken together, the capabilities of tethered lipid bilayers have opened the door to biotechnology applications in healthcare, environmental monitoring and energy storage. In this review, several examples of such applications are presented. Beyond the particulars of each example, the focus of this review is on the emerging design and characterization strategies that made these applications possible. By drawing connections between these strategies and promising research results, future opportunities for tethered lipid bilayers within the biotechnology field are discussed.

  9. Comparative genomics of biotechnologically important yeasts.

    Science.gov (United States)

    Riley, Robert; Haridas, Sajeet; Wolfe, Kenneth H; Lopes, Mariana R; Hittinger, Chris Todd; Göker, Markus; Salamov, Asaf A; Wisecaver, Jennifer H; Long, Tanya M; Calvey, Christopher H; Aerts, Andrea L; Barry, Kerrie W; Choi, Cindy; Clum, Alicia; Coughlan, Aisling Y; Deshpande, Shweta; Douglass, Alexander P; Hanson, Sara J; Klenk, Hans-Peter; LaButti, Kurt M; Lapidus, Alla; Lindquist, Erika A; Lipzen, Anna M; Meier-Kolthoff, Jan P; Ohm, Robin A; Otillar, Robert P; Pangilinan, Jasmyn L; Peng, Yi; Rokas, Antonis; Rosa, Carlos A; Scheuner, Carmen; Sibirny, Andriy A; Slot, Jason C; Stielow, J Benjamin; Sun, Hui; Kurtzman, Cletus P; Blackwell, Meredith; Grigoriev, Igor V; Jeffries, Thomas W

    2016-08-30

    Ascomycete yeasts are metabolically diverse, with great potential for biotechnology. Here, we report the comparative genome analysis of 29 taxonomically and biotechnologically important yeasts, including 16 newly sequenced. We identify a genetic code change, CUG-Ala, in Pachysolen tannophilus in the clade sister to the known CUG-Ser clade. Our well-resolved yeast phylogeny shows that some traits, such as methylotrophy, are restricted to single clades, whereas others, such as l-rhamnose utilization, have patchy phylogenetic distributions. Gene clusters, with variable organization and distribution, encode many pathways of interest. Genomics can predict some biochemical traits precisely, but the genomic basis of others, such as xylose utilization, remains unresolved. Our data also provide insight into early evolution of ascomycetes. We document the loss of H3K9me2/3 heterochromatin, the origin of ascomycete mating-type switching, and panascomycete synteny at the MAT locus. These data and analyses will facilitate the engineering of efficient biosynthetic and degradative pathways and gateways for genomic manipulation.

  10. The application of biotechnology in animal nutrition

    Directory of Open Access Journals (Sweden)

    Šefer Dragan

    2015-01-01

    Full Text Available Animal food has to incorporate multiple objectives, ie. it should provide good animal health, good production and reproductive performance, reduce pollution of the environment as well as have the impact on food of animal origin, by supplying it, in addition to basic nutrients, with certain useful substances that can act preventively on the occurrence of various diseases in humans in modern living conditions. This complex task implies the application of scientific knowledge concerning biotechnology in the field of animal feed production, and also includes the use of specific nutrients that are the result of the latest developments in specific disciplines such as molecular biology and genetic engineering. As a result of researches in these areas there were created some varieties of cereals and legumes with improved nutritional properties. On the other hand, obtaining a safe food of animal origin product imposes the use of substances of natural origin (such as probiotics, prebiotics, phytobiotics, enzymes, chelating forms .., which provide better digestibility and more complete utilization of certain nutrients from the feedstuff. In this way, the quantity of undigested substances are significantly reduced as well as soil and the atmosphere pollution. The use of specific additives in animal nutrition resulting from biotechnological research is most frequent when a problem concerning certain level of production or animal health has to be overcome. This implies a group of non-nutritional ingredients which are aimed to regulate the digestive tract microflora, pH, weight gain, as well as to modify metabolic processes etc.

  11. Biotechnological production of vanillin using immobilized enzymes.

    Science.gov (United States)

    Furuya, Toshiki; Kuroiwa, Mari; Kino, Kuniki

    2017-02-10

    Vanillin is an important and popular plant flavor, but the amount of this compound available from plant sources is very limited. Biotechnological methods have high potential for vanillin production as an alternative to extraction from plant sources. Here, we report a new approach using immobilized enzymes for the production of vanillin. The recently discovered oxygenase Cso2 has coenzyme-independent catalytic activity for the conversion of isoeugenol and 4-vinylguaiacol to vanillin. Immobilization of Cso2 on Sepabeads EC-EA anion-exchange carrier conferred enhanced operational stability enabling repetitive use. This immobilized Cso2 catalyst allowed 6.8mg yield of vanillin from isoeugenol through ten reaction cycles at a 1mL scale. The coenzyme-independent decarboxylase Fdc, which has catalytic activity for the conversion of ferulic acid to 4-vinylguaiacol, was also immobilized on Sepabeads EC-EA. We demonstrated that the immobilized Fdc and Cso2 enabled the cascade synthesis of vanillin from ferulic acid via 4-vinylguaiacol with repetitive use of the catalysts. This study is the first example of biotechnological production of vanillin using immobilized enzymes, a process that provides new possibilities for vanillin production.

  12. Plant biotechnological patents from the legal perspective

    Directory of Open Access Journals (Sweden)

    Farhah Abdullah

    2009-08-01

    Full Text Available The purpose of this article is to examine the extent to which plant biotechnological patent in terms of natural product which has human intervention, different from other product and the entitlement of such a patent whether it is the inventor or biological donor s patent? In addition, the article discusses how would one determine the value added” by the company s researchers as opposed to the value contributed by the original genetic material. Meanwhile, the poor farmers and indigenous people who are the pioneers in terms of the knowledge of the plant, they are left unprivileged and deprived of their contribution and benefits. Thus, this article would highlight the significance of the contribution made by the original donor especially, in a poor developing country whose natural heritage has been taken away without any consideration, acknowledgment and how to strike a balance between the rights of an inventor and biological donor? Keywords: Plant Biotechnology, Patents, Inventor, Biological Donor, Developing countries Received: 7 July 2009 / Received in revised form: 28 August 2009, Accepted: 28 August 2009, Published online: 22 September 2009

  13. The locks and keys to industrial biotechnology.

    Science.gov (United States)

    Wohlgemuth, Roland

    2009-04-01

    The sustainable use of resources by Nature to synthesize the required products at the right place, when they are needed, continues to be the role model for total synthesis and production in general. The combination of molecular and engineering science and technology in the biotechnological approach needs no protecting groups at all and has therefore been established for numerous large-scale routes to both natural and synthetic products in industry. The use of biobased raw materials for chemical synthesis, and the economy of molecular transformations like atom economy and step economy are of growing importance. As safety, health and environmental issues are key drivers for process improvements in the chemical industry, the development of biocatalytic reactions or pathways replacing hazardous reagents is a major focus. The integration of the biocatalytic reaction and downstream processing with product isolation has led to a variety of in situ product recovery techniques and has found numerous successful applications. With the growing collection of biocatalytic reactions, the retrosynthetic thinking can be applied to biocatalysis as well. The introduction of biocatalytic reactions is uniquely suited to cost reductions and higher quality products, as well as to more sustainable processes. The transfer of Nature's simple and robust sensing and control principles as well as its reaction and separation organization into useful technical systems can be applied to different fermentations, biotransformations and downstream processes. Biocatalyst and pathway discovery and development is the key towards new synthetic transformations in industrial biotechnology.

  14. Microbial lipases: Production, properties and biotechnological applications

    Directory of Open Access Journals (Sweden)

    Josana Maria Messias

    2011-09-01

    Full Text Available Lipases belong to the group of hydrolases that catalyze the hydrolysis of triacylglycerol lipids to free fatty acids and glycerol. They have significant potential biotechnological applications in catalyzing organic synthesis reactions in non-aqueous solvents using simplified procedures resulting in conversions of high yields. Lipase production has conventionally been performed by submerged fermentation; however, solid-state fermentation processes have been prominent when residues are used as substrates because they serve as low-cost nutrient sources. Microbial lipases can be used as additives in foods to modify and enhance organoleptic properties, as well as in detergents to hydrolyse fats in the treatment of oily effluents, and also have value for pharmaceutical, cosmetic, agrochemical, and oil chemical industries. More recently, they are used in transesterification reactions to convert plant seed oils into biodiesel. The objective of this work was to review the published literature on the production, properties and applications of microbial lipases, and its biotechnological role in producing biodiesel.

  15. Biosurfactants: Promising Molecules for Petroleum Biotechnology Advances

    Directory of Open Access Journals (Sweden)

    DARNE GERMANO DE ALMEIDA

    2016-10-01

    Full Text Available The growing global demand for sustainable technologies that improves the efficiency of petrochemical processes in the oil industry has driven advances in petroleum biotechnology in recent years. Petroleum industry uses substantial amounts of petrochemical-based synthetic surfactants in its activities as mobilizing agents to increase the availability or recovery of hydrocarbons as well as many other applications related to extraction, treatment, cleaning and transportation. However, biosurfactants have several potential applications for use across the oil processing chain and in the formulations of petrochemical products such as emulsifying/demulsifying agents, anticorrosive, biocides for sulphate-reducing bacteria, fuel formulation, extraction of bitumen from tar sands and many other innovative applications. Due to their versatility and proven efficiency, biosurfactants are often presented as valuable versatile tools that can transform and modernise petroleum biotechnology in an attempt to provide a true picture of state of the art and directions or use in the oil industry. We believe that biosurfactants are going to have a significant role in many future applications in the oil industries and in this review therefore, we highlight recent important relevant applications, patents disclosures and potential future applications for biosurfactants in petroleum and related industries.

  16. Biosurfactants: Promising Molecules for Petroleum Biotechnology Advances.

    Science.gov (United States)

    De Almeida, Darne G; Soares Da Silva, Rita de Cássia F; Luna, Juliana M; Rufino, Raquel D; Santos, Valdemir A; Banat, Ibrahim M; Sarubbo, Leonie A

    2016-01-01

    The growing global demand for sustainable technologies that improves the efficiency of petrochemical processes in the oil industry has driven advances in petroleum biotechnology in recent years. Petroleum industry uses substantial amounts of petrochemical-based synthetic surfactants in its activities as mobilizing agents to increase the availability or recovery of hydrocarbons as well as many other applications related to extraction, treatment, cleaning, and transportation. However, biosurfactants have several potential applications for use across the oil processing chain and in the formulations of petrochemical products such as emulsifying/demulsifying agents, anticorrosive, biocides for sulfate-reducing bacteria, fuel formulation, extraction of bitumen from tar sands, and many other innovative applications. Due to their versatility and proven efficiency, biosurfactants are often presented as valuable versatile tools that can transform and modernize petroleum biotechnology in an attempt to provide a true picture of state of the art and directions or use in the oil industry. We believe that biosurfactants are going to have a significant role in many future applications in the oil industries and in this review therefore, we highlight recent important relevant applications, patents disclosures and potential future applications for biosurfactants in petroleum and related industries.

  17. 75 FR 61413 - Notice of Availability of Biotechnology Quality Management System Audit Standard and Evaluation...

    Science.gov (United States)

    2010-10-05

    ... Animal and Plant Health Inspection Service Notice of Availability of Biotechnology Quality Management... has developed an audit standard for its biotechnology compliance assistance program. The audit... Assistance Branch, Biotechnology Regulatory Services, APHIS, 4700 River Road Unit 91, Riverdale, MD...

  18. 78 FR 27977 - Office of Biotechnology Activities; Recombinant DNA Research: Proposed Actions Under the NIH...

    Science.gov (United States)

    2013-05-13

    ... HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities; Recombinant DNA... Acid Molecules (NIH Guidelines) SUMMARY: The NIH Office of Biotechnology Activities (NIH OBA) proposes... by mail to the NIH Office of Biotechnology Activities, National Institutes of Health, 6705...

  19. 75 FR 1749 - Syngenta Biotechnology, Inc.; Availability of Petition and Environmental Assessment for...

    Science.gov (United States)

    2010-01-13

    ... Animal and Plant Health Inspection Service Syngenta Biotechnology, Inc.; Availability of Petition and... Biotechnology, Inc., seeking a determination of nonregulated status for corn designated as transformation event....aphis.usda.gov ). FOR FURTHER INFORMATION CONTACT: Dr. Subray Hegde, Biotechnology Regulatory...

  20. 75 FR 28811 - Office of Biotechnology Activities; Recombinant DNA Research: Proposed Actions Under the NIH...

    Science.gov (United States)

    2010-05-24

    ... HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities; Recombinant DNA... Office of Biotechnology Activities (OBA) by the Institutional Biosafety Committee at Lawrence Livermore... Biotechnology Activities, National Institutes of Health. BILLING CODE 4140-01-P...

  1. 77 FR 13258 - Biotechnology Regulatory Services; Changes Regarding the Solicitation of Public Comment for...

    Science.gov (United States)

    2012-03-06

    ... Animal and Plant Health Inspection Service Biotechnology Regulatory Services; Changes Regarding the.... FOR FURTHER INFORMATION CONTACT: Dr. T. Clint Nesbitt, Chief of Staff, Biotechnology Regulatory...://www.aphis.usda.gov/biotechnology/pet_proc_imp.shtml . Current Comment Process for Petitions...

  2. 75 FR 20560 - Syngenta Biotechnology, Inc.; Determination of Nonregulated Status for Corn Genetically...

    Science.gov (United States)

    2010-04-20

    ... Animal and Plant Health Inspection Service Syngenta Biotechnology, Inc.; Determination of Nonregulated... developed by Syngenta Biotechnology, Inc., designated as transformation event MIR162, which has been... on our evaluation of data submitted by Syngenta Biotechnology, Inc., in its petition for...

  3. 75 FR 41798 - Solicitation of Letters of Interest to Participate in Biotechnology Quality Management System...

    Science.gov (United States)

    2010-07-19

    ... Biotechnology Quality Management System Program AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION...) is soliciting letters of interest to participate in the APHIS Biotechnology Quality Management System Program. The Biotechnology Quality Management System Program is a voluntary ] compliance...

  4. Biotechnology in China II. Chemicals, energy and environment

    Energy Technology Data Exchange (ETDEWEB)

    Tsao, G.T. [Purdue Univ., West Lafayette, IN (United States). Lab. Renewable Resources Engineering; Ouyang, Pingkai [Nanjing Univ. of Technology (China). College of Life Science and Pharmaceutical Engineering; Chen, Jian (eds.) [Jiangnan Univ., Wuxi (China). School of Biotechnology

    2010-07-01

    The biochemical engineering and biotechnology is now becoming the most important industry all over the world. China, as a country that has more than 1.3 billion people, has become one of the fastest growing countries in the world during the last several decades. Both the Chinese government and companies pay more and more attention on the research and the application of biotechnology. In the 11th five-year plan (2006-2010), Chinese government unprecedented enhanced the support on the biotechnology in both policy and finance. Currently, the biotechnology gains the most R and D funding in China. With the great support and the increasingly frequent exchanges from abroad, the biotechnology in China becomes more and more important in the world. In recognition of the enormous advances in biotechnology in China, we are pleased to present the second volume of Advances in Biochemical Engineering/ Biotechnology: Biotechnology in China II, edited by P. K. Ouyang, J. Chen and G. T. Tsao, relatively soon after the introduction of the first volume of this multivolume comprehensive books. Since the previous volume was extremely well accepted by the scientific community, we have maintained the overall goal of creating a number of chapters, each devoted to a certain topic by several Chinese research groups working in the field, which provide scientists in academia and public institutions with a well-balanced and comprehensive overview of this growing field in China. We have fully revised the volume and expanded it from bioreaction, bioseparation and bioremediation to more extensive issues in order to cover all recent developments in China into account as much as possible. The new volume of Advances in Biochemical Engineering/Biotechnology: Biotechnology in China II is a comprehensive description of the state-of-the-art in China, and a guide to the understanding the work of Chinese biochemical engineering and biotechnology researchers. It is specifically directed to microbiologists

  5. A critical assessment of regulatory triggers for products of biotechnology: Product vs. process.

    Science.gov (United States)

    McHughen, Alan

    2016-10-01

    Regulatory policies governing the safety of genetic engineering (rDNA) and the resulting products (GMOs) have been contentious and divisive, especially in agricultural applications of the technologies. These tensions led to vastly different approaches to safety regulation in different jurisdictions, even though the intent of regulations-to assure public and environmental safety-are common worldwide, and even though the international scientific communities agree on the basic principles of risk assessment and risk management. So great are the political divisions that jurisdictions cannot even agree on the appropriate triggers for regulatory capture, whether product or process. This paper reviews the historical policy and scientific implications of agricultural biotechnology regulatory approaches taken by the European Union, USA and Canada, using their respective statutes and regulations, and then critically assesses the scientific underpinnings of each.

  6. Role of biotechnology in sustainable development of cotton

    Science.gov (United States)

    The prospect of biotechnology to provide cost-efficient sustainable cotton production under a safe environment for the 21st century is enormous. The role of plant biotechnology in the improvement of cotton is a rapidly evolving area and very broad. The specific objective of this paper is to provide...

  7. Teaching Biotechnology to Medical Students: Is There an Easy Way?

    Science.gov (United States)

    Steggles, Allen W.

    1987-01-01

    Discusses the teaching of biotechnology to medical students, undergraduate students and high school seniors. Suggests changes in how the basic sciences are taught in medical schools. Reviews the effects of teaching biotechnology at Northeastern Ohio Universities College of Medicine (NEOUCOM). (CW)

  8. Students' Biotechnology Literacy: The Pillars of STEM Education in Malaysia

    Science.gov (United States)

    Bahri, Nurnadiah Mohamed; Suryawati, Evi; Osman, Kamisah

    2014-01-01

    Biotechnology has been widely applied in various products throughout the 21st century. Malaysia selected the biotechnology sector as one of the key strategic technologies that would enable Malaysia to transform into a fully developed nation by the year 2020. However, to date, there has been very little research on the level of biotechnology…

  9. Using the Mystery of the Cyclopic Lamb to Teach Biotechnology

    Science.gov (United States)

    Jensen, Jamie L.

    2010-01-01

    I present a learning cycle that explores different biotechnologies using the process of in situ hybridization as a platform. Students are presented with a cyclopic lamb and must use biotechnology to discover the mechanism behind the deformity. Through this activity, students learn about signal transduction and discover the processes of polymerase…

  10. Too New for Textbooks: The Biotechnology Discoveries & Applications Guidebook

    Science.gov (United States)

    Loftin, Madelene; Lamb, Neil E.

    2013-01-01

    The "Biotechnology Discoveries and Applications" guidebook aims to provide teachers with an overview of the recent advances in genetics and biotechnology, allowing them to share these findings with their students. The annual guidebook introduces a wealth of modern genomic discoveries and provides teachers with tools to integrate exciting…

  11. Multidimensional Analysis of High-School Students' Perceptions about Biotechnology

    Science.gov (United States)

    Fonseca, Maria Joao; Costa, Patricio; Lencastre, Leonor; Tavares, Fernando

    2012-01-01

    Concerns about public understanding of biotechnology have motivated educational initiatives to improve students' competency to make scientifically sustained decisions regarding controversial issues. Understanding students' perceptions about biotechnology is essential to determine the effectiveness of these programmes. To assess how students'…

  12. Young and Robust: Tianjin Institute of Industrial Biotechnology

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The Tianjin Institute of Industrial Biotechnology (TIB) was initiated hand-in-hand by CAS and People's Government of Tianjin City in March, 2009. Located in the Tianjin Airport Economic Area, TIB has a historical mission of developing industrial biotechnology system and promoting the sustainable development of Tianjin and Bohai Bay Economic Rim.

  13. New opportunities revealed by biotechnological explorations of extremophiles.

    Science.gov (United States)

    Podar, Mircea; Reysenbach, Anna-Louise

    2006-06-01

    Over the past few decades the extremes at which life thrives has continued to challenge our understanding of biochemistry, biology and evolution. As more new extremophiles are brought into laboratory culture, they have provided a multitude of potential applications for biotechnology. More recently, innovative culturing approaches, environmental genome sequencing and whole genome sequencing have provided new opportunities for the biotechnological exploration of extremophiles.

  14. Biotechnology policies and performance in central and eastern Europe

    NARCIS (Netherlands)

    Senker, J.; Enzing, C.; Reiss, T.

    2008-01-01

    This paper assesses how far ten Central and Eastern European (CEE) countries have 'caught up' in biotechnology on the basis of information about the policies and funding for biotechnology research and commercialisation from 2002-2005 and on the research and commercialisation performance of these cou

  15. Sectoral innovation foresight. Biotechnology sector. Final Reeport. Task 2

    NARCIS (Netherlands)

    Valk, T. van der; Gijsbers, G.W.; Meis, M.

    2010-01-01

    Biotechnology has evolved from a single set of technologies in the mid 1970s (e.g. recombinant DNA technology) into the full grown economic activity of today. The set of technologies that constitute the field of biotechnology thus find their applications in different sectors, most notably in agricul

  16. [Preface for special issue on industrial biotechnology (2014)].

    Science.gov (United States)

    Zhu, Dunming; Tian, Chaoguang

    2014-01-01

    Industrial biotechnology provides practical solutions to the challenges in the areas of resources, energy and environment. Based on the 7th China Summit Forum on Industrial Biotechnology Development, this special issue reports the latest advances in the fields of bioinformatics, microbial cell factories, fermentation engineering, industrial enzymes and high throughput screening methods.

  17. Green biotechnology, nanotechnology and bio-fortification: perspectives on novel environment-friendly crop improvement strategies.

    Science.gov (United States)

    Yashveer, Shikha; Singh, Vikram; Kaswan, Vineet; Kaushik, Amit; Tokas, Jayanti

    2014-10-01

    Food insecurity and malnutrition are prominent issues for this century. As the world's population continues to increase, ensuring that the earth has enough food that is nutritious too will be a difficult task. Today one billion people of the world are undernourished and more than a third are malnourished. Moreover, the looming threat of climate change is exasperating the situation even further. At the same time, the total acreage of arable land that could support agricultural use is already near its limits, and may even decrease over the next few years due to salination and desertification patterns resulting from climate change. Clearly, changing the way we think about crop production must take place on multiple levels. New varieties of crops must be developed which can produce higher crop yields with less water and fewer agricultural inputs. Besides this, the crops themselves must have improved nutritional qualities or become biofortified in order to reduce the chances of 'hidden hunger' resulting from malnourishment. It is difficult to envision the optimum way to increase crop production using a single uniform strategy. Instead, a variety of approaches must be employed and tailored for any particular agricultural setting. New high-impact technologies such as green biotechnology, biofortification, and nanotechnology offer opportunities for boosting agricultural productivity and enhancing food quality and nutritional value with eco-friendly manner. These agricultural technologies currently under development will renovate our world to one that can comfortably address the new directions, our planet will take as a result of climate change.

  18. European attitudes on the regulation of modern biotechnology and their consequences.

    Science.gov (United States)

    Cantley, Mark

    2012-01-01

    Modern biotechnology has gradually attracted ever greater interest over the past four decades, from ever-widening communities across the world--from academic scientists, of course, and then from industrialists, journalists, medical specialists, agricultural practitioners, environmental "experts," economists, trading companies--and, so far as it concerns regulation, above all from political interests whose product is indeed legislation. As the interests widened, conflicts developed: between departments, between sectors, between countries and between international agencies. The European Community made choices, bitterly contested; the battles on conducting and regulating the field release of GMOs (genetically modified organisms) were usually won--at least in Europe--by the environment ministries, often in conflict with agriculture and/or the research and science ministries. The result has been the construction over the past 30 y of an ever heavier regulatory burden on those who seek to develop and launch products based on the use of modern biotechnology. The pretense is labeled "the precautionary principle." No lives have been saved, but many jobs have been created in bureaucracies large and small around the world. So far as academia was concerned, their experiments and field trials were repeatedly wrecked by NGOs (non-governmental organizations) claiming thus to have saved mankind and the environment. This is a story of grave political failure in Europe with globally adverse consequences.

  19. How to be Cautious but Open to Learning: Time to Update Biotechnology and GMO Legislation.

    Science.gov (United States)

    Hansson, Sven Ove

    2016-08-01

    Precautionary measures to protect human health and the environment should be science based. This implies that they should be directed at a potential danger for which there is credible scientific evidence (although that evidence need not be conclusive). Furthermore, protective measures should be updated as relevant science advances. This means that decisionmakers should be prepared to strengthen the precautionary measures if the danger turns out to be greater than initially suspected, and to reduce or lift them, should the danger prove to be smaller. Most current legislation on agricultural biotechnology has not been scientifically updated. Therefore, it reflects outdated criteria for identifying products that can cause problems. Modern knowledge in genetics, plant biology, and ecology has provided us with much better criteria that risk analysts can use to identify the potentially problematic breeding projects at which precautionary measures should be directed. Legislation on agricultural biotechnology should be scientifically updated. Furthermore, legislators should learn from this example that regulations based on the current state of science need to have inbuilt mechanisms for revisions and adjustments in response to future developments in science.

  20. Fossil energy biotechnology: A research needs assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    The Office of Program Analysis of the US Department of Energy commissioned this study to evaluate and prioritize research needs in fossil energy biotechnology. The objectives were to identify research initiatives in biotechnology that offer timely and strategic options for the more efficient and effective uses of the Nation`s fossil resource base, particularly the early identification of new and novel applications of biotechnology for the use or conversion of domestic fossil fuels. Fossil energy biotechnology consists of a number of diverse and distinct technologies, all related by the common denominator -- biocatalysis. The expert panel organized 14 technical subjects into three interrelated biotechnology programs: (1) upgrading the fuel value of fossil fuels; (2) bioconversion of fossil feedstocks and refined products to added value chemicals; and, (3) the development of environmental management strategies to minimize and mitigate the release of toxic and hazardous petrochemical wastes.

  1. New master program in management in biophotonics and biotechnologies

    Science.gov (United States)

    Meglinski, I. V.; Tuchin, V. V.

    2006-08-01

    We develop new graduate educational highly interdisciplinary program that will be useful for addressing problems in worldwide biotechnologies and related biomedical industries. This Master program called Management in Biophotonics and Biotechnologies provides students with the necessary training, education and problem-solving skills to produce managers who are better equipped to handle the challenges of modern business in modern biotechnologies. Administered jointly by Cranfield University (UK) and Saratov State University, Russia) graduates possess a blend of engineering, biotechnologies, business and interpersonal skills necessary for success in industry. The Master courses combine a regular year program in biophotonics & biotechnologies disciplines with the core requirements of a Master degree. A major advantage of the program is that it will provide skills not currently available to graduates in any other program, and it will give the graduates an extra competitive edge for getting a job then.

  2. 77 FR 16846 - National Science Advisory Board for Biosecurity Meeting; Office of Biotechnology Activities...

    Science.gov (United States)

    2012-03-22

    ...; Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of Closed...: Ronna Hill, NSABB Program Assistant, NIH Office of Biotechnology Activities, 6705 Rockledge Drive,...

  3. Biotechnology: An Era of Hopes and Fears

    Science.gov (United States)

    2016-01-01

    bird flu makes agriculture a serious target for an adversary seeking to inflict fi- nancial damage while not directly harming human life. This threat...large number of engineered bees could be raised in a protected environment; then a large population of engineered drones would be released to...of the bee population in an agriculturally in- tense geographic area could have enormous secondary effects, as crops that rely upon pollination

  4. Interfacing microbiology and biotechnology. Conference abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Maupin, Julia A.

    2001-05-19

    The Interfacing Microbiology and Biotechnology Conference was attended by over 100 faculty, post-docs, students, and research scientists from the US, Europe, and Latin America. The conference successfully stimulated communication and the dissemination of knowledge among scientists involved in basic and applied research. The focus of the conference was on microbial physiology and genetics and included sessions on C1 metabolism, archaeal metabolism, proteases and chaperones, gene arrays, and metabolic engineering. The meeting provided the setting for in-depth discussions between scientists who are internationally recognized for their research in these fields. The following objectives were met: (1) The promotion of interaction and future collaborative projects among scientists involved in basic and applied research which incorporates microbial physiology, genetics, and biochemistry; (2) the facilitation of communication of new research findings through seminars, posters, and abstracts; (3 ) the stimulation of enthusiasm and education among participants including graduate and undergraduate students.

  5. Complex Biochemistry and Biotechnological Production of Betalains

    Directory of Open Access Journals (Sweden)

    Marijana Krsnik-Rasol

    2011-01-01

    Full Text Available The demand for natural food colourants is increasing because of public awareness of their health benefits. Betalains are nitrogen-containing plant pigments whose colours range from red-violet betacyanins to yellow betaxanthins. They are used for colouring dairy products, meat and frozen desserts. Betalains have attracted additional interest because of their antioxidative, anti-inflammatory and anticarcinogenic properties. The main source of commercially produced betalains is red beet root, but alternative sources are found in plants from the Amaranthaceae and Cactaceae families. Another alternative source is plant cell culture in bioreactors, although optimization of pigment production seems necessary. In this paper we synthesize the results of recent studies on betalain biosynthesis, chemical properties, sources, biotechnology and applications.

  6. Nonclinical statistics for pharmaceutical and biotechnology industries

    CERN Document Server

    2016-01-01

    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods important to the nonclinical science areas within the pharmaceutical and biotechnology industries. Specifically the Discovery and Translational sciences, the Safety/Toxiology sciences, and the Chemistry, Manufacturing and Controls sciences. Drug discovery and development is a long and costly process. Most decisions in the drug development process are made with incomplete information. The data is rife with uncertainties and hence risky by nature. This is therefore the purview of Statistics. As such, this book aims to introduce readers to important statistical thinking and its application in these nonclinical areas. The cha...

  7. Biotechnological production of gluconic acid: future implications.

    Science.gov (United States)

    Singh, Om V; Kumar, Raj

    2007-06-01

    Gluconic acid (GA) is a multifunctional carbonic acid regarded as a bulk chemical in the food, feed, beverage, textile, pharmaceutical, and construction industries. The favored production process is submerged fermentation by Aspergillus niger utilizing glucose as a major carbohydrate source, which accompanied product yield of 98%. However, use of GA and its derivatives is currently restricted because of high prices: about US$ 1.20-8.50/kg. Advancements in biotechnology such as screening of microorganisms, immobilization techniques, and modifications in fermentation process for continuous fermentation, including genetic engineering programmes, could lead to cost-effective production of GA. Among alternative carbohydrate sources, sugarcane molasses, grape must show highest GA yield of 95.8%, and banana must may assist reducing the overall cost of GA production. These methodologies would open new markets and increase applications of GA.

  8. Restriction Enzymes in Microbiology, Biotechnology and Biochemistry

    Directory of Open Access Journals (Sweden)

    Geoffrey G. Wilson

    2012-12-01

    Full Text Available Since their discovery in the nineteen-seventies, a collection of simple enzymes termed Type II restriction endonucleases, made by microbes to ward off viral infections, have transformed molecular biology, spawned the multi-billion dollar Biotechnology industry, and yielded fundamental insights into the biochemistry of life, health and disease. In this article we describe how these enzymes were discovered, and we review their properties, organizations and genetics. We summarize current ideas about the mechanism underlying their remarkable ability to recognize and bind to specific base pair sequences in DNA, and we discuss why these ideas might not be correct. We conclude by proposing an alternative explanation for sequence-recognition that resolves certain inconsistencies and provides, in our view, a more satisfactory account of the mechanism.

  9. Application of biofilm bioreactors in white biotechnology.

    Science.gov (United States)

    Muffler, K; Lakatos, M; Schlegel, C; Strieth, D; Kuhne, S; Ulber, R

    2014-01-01

    The production of valuable compounds in industrial biotechnology is commonly done by cultivation of suspended cells or use of (immobilized) enzymes rather than using microorganisms in an immobilized state. Within the field of wastewater as well as odor treatment the application of immobilized cells is a proven technique. The cells are entrapped in a matrix of extracellular polymeric compounds produced by themselves. The surface-associated agglomerate of encapsulated cells is termed biofilm. In comparison to common immobilization techniques, toxic effects of compounds used for cell entrapment may be neglected. Although the economic impact of biofilm processes used for the production of valuable compounds is negligible, many prospective approaches were examined in the laboratory and on a pilot scale. This review gives an overview of biofilm reactors applied to the production of valuable compounds. Moreover, the characteristics of the utilized materials are discussed with respect to support of surface-attached microbial growth.

  10. Engineered transcriptional systems for cyanobacterial biotechnology.

    Science.gov (United States)

    Camsund, Daniel; Lindblad, Peter

    2014-01-01

    Cyanobacteria can function as solar-driven biofactories thanks to their ability to perform photosynthesis and the ease with which they are genetically modified. In this review, we discuss transcriptional parts and promoters available for engineering cyanobacteria. First, we go through special cyanobacterial characteristics that may impact engineering, including the unusual cyanobacterial RNA polymerase, sigma factors and promoter types, mRNA stability, circadian rhythm, and gene dosage effects. Then, we continue with discussing component characteristics that are desirable for synthetic biology approaches, including decoupling, modularity, and orthogonality. We then summarize and discuss the latest promoters for use in cyanobacteria regarding characteristics such as regulation, strength, and dynamic range and suggest potential uses. Finally, we provide an outlook and suggest future developments that would advance the field and accelerate the use of cyanobacteria for renewable biotechnology.

  11. Applications of cell sorting in biotechnology

    Directory of Open Access Journals (Sweden)

    Mattanovich Diethard

    2006-03-01

    Full Text Available Abstract Due to its unique capability to analyze a large number of single cells for several parameters simultaneously, flow cytometry has changed our understanding of the behavior of cells in culture and of the population dynamics even of clonal populations. The potential of this method for biotechnological research, which is based on populations of living cells, was soon appreciated. Sorting applications, however, are still less frequent than one would expect with regard to their potential. This review highlights important contributions where flow cytometric cell sorting was used for physiological research, protein engineering, cell engineering, specifically emphasizing selection of overproducing cell lines. Finally conclusions are drawn concerning the impact of cell sorting on inverse metabolic engineering and systems biology.

  12. The Development of TALE Nucleases for Biotechnology.

    Science.gov (United States)

    Ousterout, David G; Gersbach, Charles A

    2016-01-01

    The development of a facile genome engineering technology based on transcription activator-like effector nucleases (TALENs) has led to significant advances in diverse areas of science and medicine. In this review, we provide a broad overview of the development of TALENs and the use of this technology in basic science, biotechnology, and biomedical applications. This includes the discovery of DNA recognition by TALEs, engineering new TALE proteins to diverse targets, general advances in nuclease-based editing strategies, and challenges that are specific to various applications of the TALEN technology. We review examples of applying TALENs for studying gene function and regulation, generating disease models, and developing gene therapies. The current status of genome editing and future directions for other uses of these technologies are also discussed.

  13. Advances in biotechnology and genomics of switchgrass.

    Science.gov (United States)

    Nageswara-Rao, Madhugiri; Soneji, Jaya R; Kwit, Charles; Stewart, C Neal

    2013-05-12

    Switchgrass (Panicum virgatum L.) is a C4 perennial warm season grass indigenous to the North American tallgrass prairie. A number of its natural and agronomic traits, including adaptation to a wide geographical distribution, low nutrient requirements and production costs, high water use efficiency, high biomass potential, ease of harvesting, and potential for carbon storage, make it an attractive dedicated biomass crop for biofuel production. We believe that genetic improvements using biotechnology will be important to realize the potential of the biomass and biofuel-related uses of switchgrass. Tissue culture techniques aimed at rapid propagation of switchgrass and genetic transformation protocols have been developed. Rapid progress in genome sequencing and bioinformatics has provided efficient strategies to identify, tag, clone and manipulate many economically-important genes, including those related to higher biomass, saccharification efficiency, and lignin biosynthesis. Application of the best genetic tools should render improved switchgrass that will be more economically and environmentally sustainable as a lignocellulosic bioenergy feedstock.

  14. Engineered transcriptional systems for cyanobacterial biotechnology

    Directory of Open Access Journals (Sweden)

    Daniel eCamsund

    2014-10-01

    Full Text Available Cyanobacteria can function as solar-driven biofactories thanks to their ability to perform photosynthesis and the ease with which they are genetically modified. In this review, we discuss transcriptional parts and promoters available for engineering cyanobacteria. First, we go through special cyanobacterial characteristics that may impact engineering, including the unusual cyanobacterial RNA polymerase, sigma factors and promoter types, mRNA stability, circadian rhythm, and gene dosage effects. Then, we continue with discussing component characteristics that are desirable for synthetic biology approaches, including decoupling, modularity and orthogonality. We then summarize and discuss the latest promoters for use in cyanobacteria regarding characteristics such as regulation, strength and dynamic range and suggest potential uses. Finally, we provide an outlook and suggest future developments that would advance the field and accelerate the use of cyanobacteria for renewable biotechnology.

  15. Electroporation-based applications in biotechnology.

    Science.gov (United States)

    Kotnik, Tadej; Frey, Wolfgang; Sack, Martin; Haberl Meglič, Saša; Peterka, Matjaž; Miklavčič, Damijan

    2015-08-01

    Electroporation is already an established technique in several areas of medicine, but many of its biotechnological applications have only started to emerge; we review here some of the most promising. We outline electroporation as a phenomenon and then proceed to applications, first outlining the best established - the use of reversible electroporation for heritable genetic modification of microorganisms (electrotransformation), and then explore recent advances in applying electroporation for inactivation of microorganisms, extraction of biomolecules, and fast drying of biomass. Although these applications often aim to upscale to the industrial and/or clinical level, we also outline some important chip-scale applications of electroporation. We conclude our review with a discussion of the main challenges and future perspectives.

  16. Biotechnological significance of toxic marine dinoflagellates.

    Science.gov (United States)

    Camacho, F Garcia; Rodríguez, J Gallardo; Mirón, A Sánchez; García, M C Cerón; Belarbi, E H; Chisti, Y; Grima, E Molina

    2007-01-01

    Dinoflagellates are microalgae that are associated with the production of many marine toxins. These toxins poison fish, other wildlife and humans. Dinoflagellate-associated human poisonings include paralytic shellfish poisoning, diarrhetic shellfish poisoning, neurotoxic shellfish poisoning, and ciguatera fish poisoning. Dinoflagellate toxins and bioactives are of increasing interest because of their commercial impact, influence on safety of seafood, and potential medical and other applications. This review discusses biotechnological methods of identifying toxic dinoflagellates and detecting their toxins. Potential applications of the toxins are discussed. A lack of sufficient quantities of toxins for investigational purposes remains a significant limitation. Producing quantities of dinoflagellate bioactives requires an ability to mass culture them. Considerations relating to bioreactor culture of generally fragile and slow-growing dinoflagellates are discussed. Production and processing of dinoflagellates to extract bioactives, require attention to biosafety considerations as outlined in this review.

  17. Biomechatronic Design in Biotechnology A Methodology for Development of Biotechnological Products

    CERN Document Server

    Mandenius, Carl-Fredrik

    2011-01-01

    This cutting-edge guide on the fundamentals, theory, and applications of biomechatronic design principles Biomechatronic Design in Biotechnology presents a complete methodology of biomechatronics, an emerging variant of the mechatronics field that marries biology, electronics, and mechanics to create products where biological and biochemical, technical, human, management-and-goal, and information systems are combined and integrated in order to solve a mission that fulfills a human need. A biomechatronic product includes a biological, mechanical, and electronic part. Beginning with an overvie

  18. Sustainable Use of Biotechnology for Bioenergy Feedstocks

    Science.gov (United States)

    Moon, Hong S.; Abercrombie, Jason M.; Kausch, Albert P.; Stewart, C. Neal

    2010-10-01

    Done correctly, cellulosic bioenergy should be both environmentally and economically beneficial. Carbon sequestration and decreased fossil fuel use are both worthy goals in developing next-generation biofuels. We believe that biotechnology will be needed to significantly improve yield and digestibility of dedicated perennial herbaceous biomass feedstocks, such as switchgrass and Miscanthus, which are native to the US and China, respectively. This Forum discusses the sustainability of herbaceous feedstocks relative to the regulation of biotechnology with regards to likely genetically engineered traits. The Forum focuses on two prominent countries wishing to develop their bioeconomies: the US and China. These two countries also share a political desire and regulatory frameworks to enable the commercialization and wide release of transgenic feedstocks with appropriate and safe new genetics. In recent years, regulators in both countries perform regular inspections of transgenic field releases and seriously consider compliance issues, even though the US framework is considered to be more mature and stringent. Transgene flow continues to be a pertinent environmental and regulatory issue with regards to transgenic plants. This concern is largely driven by consumer issues and ecological uncertainties. Regulators are concerned about large-scale releases of transgenic crops that have sexually compatible crops or wild relatives that can stably harbor transgenes via hybridization and introgression. Therefore, prior to the commercialization or extensive field testing of transgenic bioenergy feedstocks, we recommend that mechanisms that ensure biocontainment of transgenes be instituted, especially for perennial grasses. A cautionary case study will be presented in which a plant’s biology and ecology conspired against regulatory constraints in a non-biomass crop perennial grass (creeping bentgrass, Agrostis stolonifera), in which biocontainment was not attained. Appropriate

  19. Biotechnology in petroleum recovery. The microbial EOR

    Energy Technology Data Exchange (ETDEWEB)

    Sen, Ramkrishna [Department of Biotechnology, Indian Institute of Technology (IIT), Kharagpur, West Bengal 721302 (India)

    2008-12-15

    Biotechnology has played a significant role in enhancing crude oil recovery from the depleted oil reservoirs to solve stagnant petroleum production, after a three-stage recovery process employing mechanical, physical and chemical methods. Biotechnologically enhanced oil recovery processes, known as microbial enhanced oil recovery (MEOR), involve stimulating indigenous reservoir microbes or injecting specially selected consortia of natural bacteria into the reservoir to produce specific metabolic events that lead to improved oil recovery. This also involves flooding with oil recovery agents produced ex situ by industrial or pilot scale fermentation. This paper essentially reviews the operating mechanisms and the progress made in enhanced oil recovery through the use of microbes and their metabolic products. Improvement in oil recovery by injecting solvents and gases or by energizing the reservoir microflora to produce them in situ for carbonate rock dissolution and reservoir re-pressurization has been enunciated. The role of biosurfactants in oil mobilization through emulsification and that of biopolymers for selective plugging of oil-depleted zones and for biofilm formation have been delineated. The spoil sport played by sulfate-reducing bacteria (SRB) in MEOR has also been briefly reviewed. The importance of mathematical models used in predicting the applicability of an MEOR strategy and the microbial growth and transport has been qualitatively discussed. The results of some laboratory studies and worldwide field trials applying ex situ and in situ MEOR technologies were compiled and interpreted. However, the potential of the MEOR technologies has not been fully realized due to poor yield of the useful microbial metabolic products, growth inhibition by accumulated toxic metabolites and longer time of incubation. A complete evaluation and assessment of MEOR from an engineering standpoint based on economics, applicability and performance is required to further

  20. Insect-derived enzymes: a treasure for industrial biotechnology and food biotechnology.

    Science.gov (United States)

    Mika, Nicole; Zorn, Holger; Rühl, Martin

    2013-01-01

    Insects are the most diverse group of organisms on earth, colonizing almost every ecological niche of the planet. To survive in various and sometimes extreme habitats, insects have established diverse biological and chemical systems. Core components of these systems are enzymes that enable the insects to feed on diverse nutrient sources. The enzymes are produced by either the insects themselves (homologous) or by symbiotic organisms located in the insects' bodies or in their nests (heterologous). The use of these insect-associated enzymes for applications in the fields of food biotechnology and industrial (white) biotechnology is gaining more and more interest. Prominent examples of insect-derived enzymes include peptidases, amylases, lipases, and β-D-glucosidases. Highly potent peptidases for the degradation of gluten, a storage protein that can cause intestinal disorders, may be received from grain pests. Several insects, such as bark and ambrosia beetles and termites, are able to feed on wood. In the field of white biotechnology, their cellulolytic enzyme systems of mainly endo-1,4-β-D-glucanases and β-D-glucosidases can be employed for saccharification of the most prominent polymer on earth-cellulose.

  1. The role of industry in international animal agriculture.

    Science.gov (United States)

    Peel, C J

    1996-06-01

    The role of agribusiness and the linkages needed with other organizations and governments to be effective in developing countries are examined. After these links are established, then the strengths of business (organizing knowledge, capital, and people into productive and profitable enterprises) can contribute to improved agricultural productivity in developing countries. Technologies and products already transferred and examples of future products of biotechnology (bovine somatotropin to increase milk production and virus-resistant sweet potatoes) are discussed. Higher input systems can be successful in developing countries, as exemplified by the Saskawa-Global 2000 project, which had doubled crop yields of small-holders in some of the poorest countries of West Africa. Combining the forces of U.S. agriculture and its related agribusiness and the new products of biotechnology, the United States has an opportunity to provide the leadership in both a moral and material way to ensure there is sufficient food for all people as we move into the third millennium.

  2. A bibliometric assessment of ASEAN collaboration in plant biotechnology

    KAUST Repository

    Payumo, Jane

    2015-04-03

    This study draws on publication and citation data related to plant biotechnology from a 10-year (2004–2013) period to assess the research performance, impact, and collaboration of member states of the Association of Southeast Asian Nations (ASEAN). Plant biotechnology is one of the main areas of cooperation between ASEAN member states and among the research areas promoted to achieve regional food security and sustainable development. In general, findings indicate increased scientific output, influence, and overall collaboration of ASEAN countries in plant biotechnology over time. Research performance and collaboration (domestic, regional, and international) of the region in plant biotechnology are linked to the status of the economic development of each member country. Thailand produced the most publications of the ASEAN member states while Singapore had the highest influence as indicated by its citation activity in plant biotechnology among the ASEAN countries. Domestic and international collaborations on plant biotechnology are numerous. Regional collaboration or partnership among ASEAN countries was, however, was found to be very limited, which is a concern for the region’s goal of economic integration and science and technology cooperation. More studies using bibliometric data analysis need to be conducted to understand plant biotechnology cooperation and knowledge flows between ASEAN countries. © 2015 Akadémiai Kiadó, Budapest, Hungary

  3. Biotechnology in the 21st Century (Review Paper

    Directory of Open Access Journals (Sweden)

    M.R. Das

    2001-10-01

    Full Text Available The two technologies that will essentially determine the shape of things to come in the present century are biotechnology and information technology. A merger of biotechnology and information technology is happening right now, a significant example of which is the success of the human genome project. Biotechnology can be said to have started with the unravelling of the structure of DNA in 1953. The next decade saw exciting developments in our understanding of the fundamentals of functioning of biological system, including the role of DNA in protein synthesis. The discovery of reverse transcriptase and restriction enzymes in 1970s paved the way for further advances, including recombinant DNA and hybridoma technologies, often called 'genetic engineering'. The discovery of polymerase chain reaction in 1986 laid the foundation for large-scale applications of biotechnology in various fields. The practical applications of mapping of the entire human genome would be enormous in terms of better overall health care (diagnosis, therapy and management of disorders. In the field of flora and fauna, it generally happens that biotechnologically-rich countries have poor biodiversity and vice versa. But countries like India and China that have rich biodiversity have, by the use of biotechnology, the potential to become also biotechnologically rich.

  4. How can developing countries harness biotechnology to improve health?

    Science.gov (United States)

    Daar, Abdallah S; Berndtson, Kathryn; Persad, Deepa L; Singer, Peter A

    2007-01-01

    Background The benefits of genomics and biotechnology are concentrated primarily in the industrialized world, while their potential to combat neglected diseases in the developing world has been largely untapped. Without building developing world biotechnology capacity to address local health needs, this disparity will only intensify. To assess the potential of genomics to address health needs in the developing world, the McLaughlin-Rotman Centre for Global Health, along with local partners, organized five courses on Genomics and Public Health Policy in the developing world. The overall objective of the courses was to collectively explore how to best harness genomics to improve health in each region. This article presents and analyzes the recommendations from all five courses. Discussion In this paper we analyze recommendations from 232 developing world experts from 58 countries who sought to answer how best to harness biotechnology to improve health in their regions. We divide their recommendations into four categories: science; finance; ethics, society and culture; and politics. Summary The Courses' recommendations can be summarized across the four categories listed above: Science - Collaborate through national, regional, and international networks - Survey and build capacity based on proven models through education, training, and needs assessments Finance - Develop regulatory and intellectual property frameworks for commercialization of biotechnology - Enhance funding and affordability of biotechnology - Improve the academic-industry interface and the role of small and medium enterprise Ethics, Society, Culture - Develop public engagement strategies to inform and educate the public about developments in genomics and biotechnology - Develop capacity to address ethical, social and cultural issues - Improve accessibility and equity Politics - Strengthen understanding, leadership and support at the political level for biotechnology - Develop policies outlining

  5. How can developing countries harness biotechnology to improve health?

    Directory of Open Access Journals (Sweden)

    Persad Deepa L

    2007-12-01

    Full Text Available Abstract Background The benefits of genomics and biotechnology are concentrated primarily in the industrialized world, while their potential to combat neglected diseases in the developing world has been largely untapped. Without building developing world biotechnology capacity to address local health needs, this disparity will only intensify. To assess the potential of genomics to address health needs in the developing world, the McLaughlin-Rotman Centre for Global Health, along with local partners, organized five courses on Genomics and Public Health Policy in the developing world. The overall objective of the courses was to collectively explore how to best harness genomics to improve health in each region. This article presents and analyzes the recommendations from all five courses. Discussion In this paper we analyze recommendations from 232 developing world experts from 58 countries who sought to answer how best to harness biotechnology to improve health in their regions. We divide their recommendations into four categories: science; finance; ethics, society and culture; and politics. Summary The Courses' recommendations can be summarized across the four categories listed above: Science - Collaborate through national, regional, and international networks - Survey and build capacity based on proven models through education, training, and needs assessments Finance - Develop regulatory and intellectual property frameworks for commercialization of biotechnology - Enhance funding and affordability of biotechnology - Improve the academic-industry interface and the role of small and medium enterprise Ethics, Society, Culture - Develop public engagement strategies to inform and educate the public about developments in genomics and biotechnology - Develop capacity to address ethical, social and cultural issues - Improve accessibility and equity Politics - Strengthen understanding, leadership and support at the political level for biotechnology

  6. Advances in biomedical engineering and biotechnology during 2013-2014.

    Science.gov (United States)

    Liu, Feng; Wang, Ying; Burkhart, Timothy A; González Penedo, Manuel Francisco; Ma, Shaodong

    2014-01-01

    The 3rd International Conference on Biomedical Engineering and Biotechnology (iCBEB 2014), held in Beijing from the 25th to the 28th of September 2014, is an annual conference that intends to provide an opportunity for researchers and practitioners around the world to present the most recent advances and future challenges in the fields of biomedical engineering, biomaterials, bioinformatics and computational biology, biomedical imaging and signal processing, biomechanical engineering and biotechnology, amongst others. The papers published in this issue are selected from this conference, which witnesses the advances in biomedical engineering and biotechnology during 2013-2014.

  7. Legislation on biotechnology in the Nordic Countries - an overview 2016

    DEFF Research Database (Denmark)

    Kvale, Hallvard; Gudmundsdóttir, Laufey Helga; Stoll, Jane;

    This overview on the legislation of biotechnology in the Nordic Countries from The Nordic Committee on Bioethics provides an overview over the core biomedical legislation in the Nordic Countries, thus facilitating management of cross-border activities....

  8. Biotech 101: an educational outreach program in genetics and biotechnology.

    Science.gov (United States)

    East, Kelly M; Hott, Adam M; Callanan, Nancy P; Lamb, Neil E

    2012-10-01

    Recent advances in research and biotechnology are making genetics and genomics increasingly relevant to the lives and health of the general public. For the public to make informed healthcare and public policy decisions relating to genetic information, there is a need for increased genetic literacy. Biotech 101 is a free, short-course for the local community introducing participants to topics in genetics, genomics, and biotechnology, created at the HudsonAlpha Institute for Biotechnology. This study evaluated the effectiveness of Biotech 101 in increasing the genetic literacy of program participants through pre-and-post surveys. Genetic literacy was measured through increases in self-perceived knowledge for each content area covered through the course and the self-reported impact the course had on various aspects of participants' lives. Three hundred ninety-two individuals attended Biotech 101 during the first three course offerings. Participants reported a significant increase in self-perceived knowledge for each content area (p biotechnology.

  9. New biotechnological applications for Ashbya gossypii: Challenges and perspectives.

    Science.gov (United States)

    Aguiar, Tatiana Q; Silva, Rui; Domingues, Lucília

    2016-10-28

    The filamentous fungus Ashbya gossypii has long been considered a paradigm of the White Biotechnology in what concerns riboflavin production. Its industrial relevance led to the development of a significant molecular and in silico modeling toolbox for its manipulation. This, together with the increasing knowledge of its genome and metabolism has helped designing effective metabolic engineering strategies for optimizing riboflavin production, but also for developing new A. gossypii strains for novel biotechnological applications, such as production of recombinant proteins, single cell oils (SCOs), and flavour compounds. With the recent availability of its genome-scale metabolic model, the exploration of the full biotechnological potential of A. gossypii is now in the spotlight. Here, we will discuss some of the challenges that these emerging A. gossypii applications still need to overcome to become economically attractive and will present future perspectives for these and other possible biotechnological applications for A. gossypii.

  10. Potential of industrial biotechnology with cyanobacteria and eukaryotic microalgae.

    NARCIS (Netherlands)

    Wijffels, R.H.; Kruse, O.; Hellingwerf, K.J.

    2013-01-01

    Both cyanobacteria and eukaryotic microalgae are promising organisms for sustainable production of bulk products such as food, feed, materials, chemicals and fuels. In this review we will summarize the potential and current biotechnological developments. Cyanobacteria are promising host organisms fo

  11. Marine biotechnology advances towards applications in new functional foods.

    Science.gov (United States)

    Freitas, Ana C; Rodrigues, Dina; Rocha-Santos, Teresa A P; Gomes, Ana M P; Duarte, Armando C

    2012-01-01

    The marine ecosystem is still an untapped reservoir of biologically active compounds, which have considerable potential to supply food ingredients towards development of new functional foods. With the goal of increasing the availability and chemical diversity of functional marine ingredients, much research has been developed using biotechnological tools to discover and produce new compounds. This review summarizes the advances in biotechnological tools for production of functional ingredients, including enzymes, for the food industry. Tools involving biotechnological processes (bioreactors, fermentations, bioprocessing) and those involving genetic research designated as molecular biotechnology are discussed highlighting how they can be used in the controlled manipulation and utilization of marine organisms as sources of food ingredients, as well as discussing the most relevant shortcomings towards applications in new functional foods.

  12. Lichens as natural sources of biotechnologically relevant bacteria.

    Science.gov (United States)

    Suzuki, Marcelino T; Parrot, Delphine; Berg, Gabriele; Grube, Martin; Tomasi, Sophie

    2016-01-01

    The search for microorganisms from novel sources and in particular microbial symbioses represents a promising approach in biotechnology. In this context, lichens have increasingly become a subject of research in microbial biotechnology, particularly after the recognition that a diverse community of bacteria other than cyanobacteria is an additional partner to the traditionally recognized algae-fungus mutualism. Here, we review recent studies using culture-dependent as well as culture-independent approaches showing that lichens can harbor diverse bacterial families known for the production of compounds of biotechnological interest and that several microorganisms isolated from lichens, in particular Actinobacteria and Cyanobacteria, can produce a number of bioactive compounds, many of them with biotechnological potential.

  13. Patho-biotechnology: using bad bugs to do good things.

    Science.gov (United States)

    Sleator, Roy D; Hill, Colin

    2006-04-01

    Pathogenic bacteria have evolved sophisticated strategies to overcome host defences, to interact with the immune system and to interfere with essential host systems. We coin the term 'patho-biotechnology' to describe the exploitation of these valuable traits in biotechnology, medicine and food. This approach shows promise for the development of novel vaccine and drug delivery systems, as well as for the design of more technologically robust and effective probiotic cultures with improved biotechnological and clinical applications. The genetic tractability of Listeria monocytogenes, the availability of the complete genome sequence of this intracellular pathogen, its ability to cope with stress, and its ability to traverse the gastrointestinal tract and induce a strong cellular immune response make L. monocytogenes an ideal model organism for demonstrating the patho-biotechnology concept.

  14. A European Competence Framework for Industrial Pharmacy Practice in Biotechnology

    OpenAIRE

    Jeffrey Atkinson; Pat Crowley; Kristien De Paepe; Brian Gennery; Andries Koster; Luigi Martini; Vivien Moffat; Jane Nicholson; Gunther Pauwels; Giuseppe Ronsisvalle; Vitor Sousa; Chris van Schravendijk; Keith Wilson

    2015-01-01

    The PHAR-IN (“Competences for industrial pharmacy practice in biotechnology”) looked at whether there is a difference in how industrial employees and academics rank competences for practice in the biotechnological industry. A small expert panel consisting of the authors of this paper produced a biotechnology competence framework by drawing up an initial list of competences then ranking them in importance using a three-stage Delphi process. The framework was next evaluated and validated by a l...

  15. A REVIEW ON REGULATORY ASPECTS OF BIOTECHNOLOGY DERIVED PRODUCT

    OpenAIRE

    Modh Nehal M; Patel P.M; Patel N. M.

    2011-01-01

    Biotechnology-derived pharmaceuticals are a well established and growing part of the therapeutic armamentarium. Beginning with recombinant versions of products such as insulin that were previously manufactured by extraction from animal and human sources, licensed biotechnology drugs and those in development now span an ever-increasing range of product types and therapeutic categories. As a consequence of this diversity, both general and product class-specific scientific guidelines have been d...

  16. Chronological development avenues in biotechnology across the world

    OpenAIRE

    2011-01-01

    Biotechnology is expected to be a great technological revolution followed by information technology. It is an application of scientific and engineering principles to the processing of material by biological agents to provide better goods and services to mankind. Commercially its techniques are applied long back in 6 th century in the art of brewing, wine making and baking. It has progressed there after crossing different land marks. Modern biotechnology has developed significantly in the late...

  17. Introduction of Shanghai Hua Xin High-Biotechnology Inc.

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Shanghai Hua Xin High-Biotechnology Inc.,jointly sponsored by Hong Kong Pharmaceutical(Group) Co., Ltd., Shanghai Life Science Researching Institute of China Academy of Science, was founded in 1992, it is situated in Shanghai Biotechnology Industrial Garden. Prof. Liu Xinyuan, the founder of the company has been laureated three Academicians, including Academician of Chinese Academy of Science, Foreign Academician of National Academy of Ukraine,Academician of The Third World Academy of Science in 2001.

  18. Application of biotechnology to PCB disposal problems. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Terhorst, E.G.; Attaway, L.D.; Peyton, T.O.

    1985-05-01

    Results are presented of a study addressing the feasibility of using biotechnology to help solve the electric utility industry's PCB disposal problems. The study investigates those charateristics of PCB waste which influence biodegradation, the reported pathways and rates of degradation, the biotechnologies which appear to hold promise as treatment approaches, and the types of research and development which should be pursued to lead to commercial applications. 160 refs.

  19. A comparison of the Lithuanian and Russian Biotechnology sectors

    OpenAIRE

    Vincentas Giedraitis; Alina Alekseyko

    2012-01-01

    The goal of this paper is to compare the development of the Lithuanian and Russian biotechnology sectors. In case of Lithuania we tried to uncover what are the circumstances surrounding the favorable development of the biotechnology sectors in Lithuania. In case of Russian Federation we looked at encouraging as well as discouraging circumstances surrounding this segment of economy. Drawing upon Schumpeter’s ideas of innovation and Porter’s business cluster theory, we argue that Lithuania is “...

  20. Role of biotechnology in textile industry: а review

    OpenAIRE

    Mojsov, Kiro

    2013-01-01

    Textile processing is a growing industry that traditionally has used a lot of water, energy and harsh chemicals. They are also not easily biodegradable. Biotechnology in textiles is one of the revolutionary ways to advance the textile field. Biotechnology offers the potential for new industrial processes that require less energy and are based on renewable raw materials, as well as the application of green technologies with low energy consumption and environmentally healthy practices. Due to t...

  1. Plant protoplasts: status and biotechnological perspectives.

    Science.gov (United States)

    Davey, Michael R; Anthony, Paul; Power, J Brian; Lowe, Kenneth C

    2005-03-01

    Plant protoplasts ("naked" cells) provide a unique single cell system to underpin several aspects of modern biotechnology. Major advances in genomics, proteomics, and metabolomics have stimulated renewed interest in these osmotically fragile wall-less cells. Reliable procedures are available to isolate and culture protoplasts from a range of plants, including both monocotyledonous and dicotyledonous crops. Several parameters, particularly the source tissue, culture medium, and environmental factors, influence the ability of protoplasts and protoplast-derived cells to express their totipotency and to develop into fertile plants. Importantly, novel approaches to maximise the efficiency of protoplast-to-plant systems include techniques already well established for animal and microbial cells, such as electrostimulation and exposure of protoplasts to surfactants and respiratory gas carriers, especially perfluorochemicals and hemoglobin. However, despite at least four decades of concerted effort and technology transfer between laboratories worldwide, many species still remain recalcitrant in culture. Nevertheless, isolated protoplasts are unique to a range of experimental procedures. In the context of plant genetic manipulation, somatic hybridisation by protoplast fusion enables nuclear and cytoplasmic genomes to be combined, fully or partially, at the interspecific and intergeneric levels to circumvent naturally occurring sexual incompatibility barriers. Uptake of isolated DNA into protoplasts provides the basis for transient and stable nuclear transformation, and also organelle transformation to generate transplastomic plants. Isolated protoplasts are also exploited in numerous miscellaneous studies involving membrane function, cell structure, synthesis of pharmaceutical products, and toxicological assessments. This review focuses upon the most recent developments in protoplast-based technologies.

  2. Isolation and Purification of Biotechnological Products

    Science.gov (United States)

    Hubbuch, Jürgen; Kula, Maria-Regina

    2007-05-01

    The production of modern pharma proteins is one of the most rapid growing fields in biotechnology. The overall development and production is a complex task ranging from strain development and cultivation to the purification and formulation of the drug. Downstream processing, however, still accounts for the major part of production costs. This is mainly due to the high demands on purity and thus safety of the final product and results in processes with a sequence of typically more than 10 unit operations. Consequently, even if each process step would operate at near optimal yield, a very significant amount of product would be lost. The majority of unit operations applied in downstream processing have a long history in the field of chemical and process engineering; nevertheless, mathematical descriptions of the respective processes and the economical large-scale production of modern pharmaceutical products are hampered by the complexity of the biological feedstock, especially the high molecular weight and limited stability of proteins. In order to develop new operational steps as well as a successful overall process, it is thus a necessary prerequisite to develop a deeper understanding of the thermodynamics and physics behind the applied processes as well as the implications for the product.

  3. Plant biotechnology for lignocellulosic biofuel production.

    Science.gov (United States)

    Li, Quanzi; Song, Jian; Peng, Shaobing; Wang, Jack P; Qu, Guan-Zheng; Sederoff, Ronald R; Chiang, Vincent L

    2014-12-01

    Lignocelluloses from plant cell walls are attractive resources for sustainable biofuel production. However, conversion of lignocellulose to biofuel is more expensive than other current technologies, due to the costs of chemical pretreatment and enzyme hydrolysis for cell wall deconstruction. Recalcitrance of cell walls to deconstruction has been reduced in many plant species by modifying plant cell walls through biotechnology. These results have been achieved by reducing lignin content and altering its composition and structure. Reduction of recalcitrance has also been achieved by manipulating hemicellulose biosynthesis and by overexpression of bacterial enzymes in plants to disrupt linkages in the lignin-carbohydrate complexes. These modified plants often have improved saccharification yield and higher ethanol production. Cell wall-degrading (CWD) enzymes from bacteria and fungi have been expressed at high levels in plants to increase the efficiency of saccharification compared with exogenous addition of cellulolytic enzymes. In planta expression of heat-stable CWD enzymes from bacterial thermophiles has made autohydrolysis possible. Transgenic plants can be engineered to reduce recalcitrance without any yield penalty, indicating that successful cell wall modification can be achieved without impacting cell wall integrity or plant development. A more complete understanding of cell wall formation and structure should greatly improve lignocellulosic feedstocks and reduce the cost of biofuel production.

  4. [Peptide phage display in biotechnology and biomedicine].

    Science.gov (United States)

    Kuzmicheva, G A; Belyavskaya, V A

    2016-07-01

    To date peptide phage display is one of the most common combinatorial methods used for identifying specific peptide ligands. Phage display peptide libraries containing billions different clones successfully used for selection of ligands with high affinity and selectivity toward wide range of targets including individual proteins, bacteria, viruses, spores, different kind of cancer cells and variety of nonorganic targets (metals, alloys, semiconductors etc.) Success of using filamentous phage in phage display technologies relays on the robustness of phage particles and a possibility to genetically modify its DNA to construct new phage variants with novel properties. In this review we are discussing characteristics of the most known non-commercial peptide phage display libraries of different formats (landscape libraries in particular) and their successful applications in several fields of biotechnology and biomedicine: discovery of peptides with diagnostic values against different pathogens, discovery and using of peptides recognizing cancer cells, trends in using of phage display technologies in human interactome studies, application of phage display technologies in construction of novel nano materials.

  5. Bioprospecting and biotechnological applications of fungal laccase.

    Science.gov (United States)

    Upadhyay, Pooja; Shrivastava, Rahul; Agrawal, Pavan Kumar

    2016-06-01

    Laccase belongs to a small group of enzymes called the blue multicopper oxidases, having the potential ability of oxidation. It belongs to enzymes, which have innate properties of reactive radical production, but its utilization in many fields has been ignored because of its unavailability in the commercial field. There are diverse sources of laccase producing organisms like bacteria, fungi and plants. In fungi, laccase is present in Ascomycetes, Deuteromycetes, Basidiomycetes and is particularly abundant in many white-rot fungi that degrade lignin. Laccases can degrade both phenolic and non-phenolic compounds. They also have the ability to detoxify a range of environmental pollutants. Due to their property to detoxify a range of pollutants, they have been used for several purposes in many industries including paper, pulp, textile and petrochemical industries. Some other application of laccase includes in food processing industry, medical and health care. Recently, laccase has found applications in other fields such as in the design of biosensors and nanotechnology. The present review provides an overview of biological functions of laccase, its mechanism of action, laccase mediator system, and various biotechnological applications of laccase obtained from endophytic fungi.

  6. Biotechnological production and application of fructooligosaccharides.

    Science.gov (United States)

    Flores-Maltos, Dulce A; Mussatto, Solange I; Contreras-Esquivel, Juan C; Rodríguez-Herrera, Raúl; Teixeira, José A; Aguilar, Cristóbal N

    2016-01-01

    Currently, prebiotics are all carbohydrates of relatively short chain length. One important group is the fructooligosaccharides (FOS), a special kind of prebiotic associated to the selective stimulation of the activity of certain groups of colonic bacteria. They have a positive and beneficial effect on intestinal microbiota, reducing the incidence of gastrointestinal infections and also possessing a recognized bifidogenic effect. Traditionally, these prebiotic compounds have been obtained through extraction processes from some plants, as well as through enzymatic hydrolysis of sucrose. However, different fermentative methods have also been proposed for the production of FOS, such as solid-state fermentations utilizing various agro-industrial by-products. By optimizing the culture parameters, FOS yields and productivity can be improved. The use of immobilized enzymes and cells has also been proposed as being an effective and economic method for large-scale production of FOS. This article is an overview of the results considering recent studies on FOS biosynthesis, physicochemical properties, sources, biotechnological production and applications.

  7. [Biotechnological advances in infectious diseases diagnosis].

    Science.gov (United States)

    Hernández-Hernández, Fidel de la Cruz; Rodríguez, Mario H

    2009-01-01

    The detection of molecules of pathogens (antigens and genetic material) and host molecules in response to infections (antibodies) is the basic principle involved in molecular diagnostic tests. These tests have avoided the need to detect the attacking pathogen. New advances in molecular biology and the development of robotic technology and genomic and protein sequencing have allowed for the development of new high performance and highly specific tests. Genomics and proteomics contribute to the identification of biomarkers and biotechnology provides methods to produce high purity reagents. The identification of coding genes of specific antigens, their cloning and recombinant production, the production of monoclonal antibodies, their fragments and single chain antibodies enabled new, safer, high sensitivity and specificity immunological techniques to develop. New recognition molecules, including aptamers, will soon replace the need to produce antibodies by immunization. For the detection of genetic material, new methodological strategies based on hybridization and amplification (PCR, end point and real time) in multiplex and microarray formats have been developed, and for their detection new reporter molecules have been designed that enable their quantification. Although these methods require sophisticated instrumentation, they will soon be accessible for application in public health.

  8. Designer cell signal processing circuits for biotechnology.

    Science.gov (United States)

    Bradley, Robert W; Wang, Baojun

    2015-12-25

    Microorganisms are able to respond effectively to diverse signals from their environment and internal metabolism owing to their inherent sophisticated information processing capacity. A central aim of synthetic biology is to control and reprogramme the signal processing pathways within living cells so as to realise repurposed, beneficial applications ranging from disease diagnosis and environmental sensing to chemical bioproduction. To date most examples of synthetic biological signal processing have been built based on digital information flow, though analogue computing is being developed to cope with more complex operations and larger sets of variables. Great progress has been made in expanding the categories of characterised biological components that can be used for cellular signal manipulation, thereby allowing synthetic biologists to more rationally programme increasingly complex behaviours into living cells. Here we present a current overview of the components and strategies that exist for designer cell signal processing and decision making, discuss how these have been implemented in prototype systems for therapeutic, environmental, and industrial biotechnological applications, and examine emerging challenges in this promising field.

  9. Magnetic separations: From steel plants to biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Cafer T. Yavuz; Arjun Prakash; J.T. Mayo; Vicki L. Colvin [Rice University, Houston, TX (United States). Department of Chemistry

    2009-05-15

    Magnetic separations have for decades been essential processes in diverse industries ranging from steel production to coal desulfurization. In such settings magnetic fields are used in continuous flow processes as filters to remove magnetic impurities. High gradient magnetic separation (HGMS) has found even broader use in wastewater treatment and food processing. Batch scale magnetic separations are also relevant in industry, particularly biotechnology where fixed magnetic separators are used to purify complex mixtures for protein isolation, cell separation, drug delivery, and biocatalysis. In this review, we introduce the basic concepts behind magnetic separations and summarize a few examples of its large scale application. HGMS systems and batch systems for magnetic separations have been developed largely in parallel by different communities. However, in this work we compare and contrast each approach so that investigators can approach both key areas. Finally, we discuss how new advances in magnetic materials, particularly on the nanoscale, as well as magnetic filter design offer new opportunities for industries that have challenging separation problems.

  10. Exopolysaccharides from extremophiles: from fundamentals to biotechnology.

    Science.gov (United States)

    Nicolaus, Barbara; Kambourova, Margarita; Oner, Ebru Toksoy

    2010-09-01

    Exopolysaccharides (EPSs) make up a substantial component of the extracellular polymers surrounding most microbial cells in extreme environments like Antarctic ecosystems, saline lakes, geothermal springs or deep sea hydrothermal vents. The extremophiles have developed various adaptations, enabling them to compensate for the deleterious effects of extreme conditions, e.g. high temperatures, salt, low pH or temperature, high radiation. Among these adaptation strategies, EPS biosynthesis is one of the most common protective mechanisms. The unusual metabolic pathways revealed in some extremophiles raised interest in extremophilic microorganisms as potential producers of EPSs with novel and unusual characteristics and functional activities under extreme conditions. Even though the accumulated knowledge on the structural and theological properties of EPSs from extremophiles is still very limited, it reveals a variety in properties, which may not be found in more traditional polymers. Both extremophilic microorganisms and their EPSs suggest several biotechnological advantages, like short fermentation processes for thermophiles and easily formed and stable emulsions of EPSs from psychrophiles. Unlike mesophilic producers of EPSs, many of them being pathogenic, extremophilic microorganisms provide non-pathogenic products, appropriate for applications in the food, pharmaceutical and cosmetics industries as emulsifiers, stabilizers, gel agents, coagulants, thickeners and suspending agents. The commercial value of EPSs synthesized by microorganisms from extreme habitats has been established recently.

  11. Potential of carbon nanotubes in algal biotechnology.

    Science.gov (United States)

    Lambreva, Maya Dimova; Lavecchia, Teresa; Tyystjärvi, Esa; Antal, Taras Kornelievich; Orlanducci, Silvia; Margonelli, Andrea; Rea, Giuseppina

    2015-09-01

    A critical mass of knowledge is emerging on the interactions between plant cells and engineered nanomaterials, revealing the potential of plant nanobiotechnology to promote and support novel solutions for the development of a competitive bioeconomy. This knowledge can foster the adoption of new methodological strategies to empower the large-scale production of biomass from commercially important microalgae. The present review focuses on the potential of carbon nanotubes (CNTs) to enhance photosynthetic performance of microalgae by (i) widening the spectral region available for the energy conversion reactions and (ii) increasing the tolerance of microalgae towards unfavourable conditions occurring in mass production. To this end, current understanding on the mechanisms of uptake and localization of CNTs in plant cells is discussed. The available ecotoxicological data were used in an attempt to assess the feasibility of CNT-based applications in algal biotechnology, by critically correlating the experimental conditions with the observed adverse effects. Furthermore, main structural and physicochemical properties of single- and multi-walled CNTs and common approaches for the functionalization and characterization of CNTs in biological environment are presented. Here, we explore the potential that nanotechnology can offer to enhance functions of algae, paving the way for a more efficient use of photosynthetic algal systems in the sustainable production of energy, biomass and high-value compounds.

  12. Agriculture ideas and modernization of agriculture

    Directory of Open Access Journals (Sweden)

    Li Kangmin

    2011-12-01

    Full Text Available The development of agriculture has its own history from primitive agriculture, traditional agriculture to modem agriculture. Is it a historical road we must follow?Human being had experienced a long history of living on collection and hunting for about 2,000 to 3,000 millenniums since human being appeared on earth. After we settled down, another 10 millenniums passed. Human being began to cultivate crops and raise animals. Thus, we entered the primitive agriculture stage. The primitive agriculture lasted for 7,000 years to get our food security on primitive crop cultivation and animal raising.

  13. Fossil energy biotechnology: A research needs assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Finnerty, W.R. [Consultec Scientific, Inc., Knoxville, TN (United States)

    1992-04-01

    The Office of Program Analysis of the US Department of Energy commissioned this study to evaluate and prioritize research needs in fossil energy biotechnology. The objectives were to identify research initiatives in biotechnology that offer timely and strategic options for the more efficient and effective uses of the Nation`s fossil resource base, particularly the early identification of new and novel applications of biotechnology for the use or conversion of domestic fossil fuels. Fossil energy biotechnology consists of a number of diverse and distinct technologies, all related by the common denominator -- biocatalysis. The expert panel organized 14 technical subjects into three interrelated biotechnology programs: (1) upgrading the fuel value of fossil fuels; (2) bioconversion of fossil feedstocks and refined products to added value chemicals; and, (3) the development of environmental management strategies to minimize and mitigate the release of toxic and hazardous petrochemical wastes. The integration of these programs as viable bioprocessing initiatives proposes an innovative and conceptual principle for the development of a ``new`` approach to fossil energy biotechnology. This unifying principle is NON-AQUEOUS BIOCATALYSIS. Biocatalysis coupled to conventional chemical catalysis in organic-based media offers bioprocessing options uniquely characterized by the selectivity of biocatalysts plus fast reaction rates and specificity of chemical catalysts.

  14. NABIC marker database: A molecular markers information network of agricultural crops

    OpenAIRE

    2013-01-01

    In 2013, National Agricultural Biotechnology Information Center (NABIC) reconstructs a molecular marker database for useful genetic resources. The web-based marker database consists of three major functional categories: map viewer, RSN marker and gene annotation. It provides 7250 marker locations, 3301 RSN marker property, 3280 molecular marker annotation information in agricultural plants. The individual molecular marker provides information such as marker name, expressed sequence tag number...

  15. Proceedings of the 2. Annual Agri-Food Innovation Forum held in conjunction with the World Congress on Industrial Biotechnology and Bioprocessing

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The Agri-Food Innovation Forum was attended by leaders in innovation for agriculture and forestry and its impact on bioproduct development. The presentations addressed issues of interest to public and private sector scientists, researchers, agricultural and forestry producers as well as business innovators who focus on the agriculture and forestry sectors as suppliers of raw materials for value added products. The forum provided an opportunity to network and interact with key leaders in biotechnology. The forum highlighted the following recent contributions by Canadians to agricultural innovation: producing cellulose ethanol from agricultural wastes; optimizing oil seed potential for industrial applications; producing biogas from manures; the auto industry's interest in biomaterials; and, fibres and polymers from lignocellulosic sources. The forum featured 7 presentations, of which 2 have been catalogued separately for inclusion in this database. refs., tabs., figs.

  16. Nanobody-derived nanobiotechnology tool kits for diverse biomedical and biotechnology applications.

    Science.gov (United States)

    Wang, Yongzhong; Fan, Zhen; Shao, Lei; Kong, Xiaowei; Hou, Xianjuan; Tian, Dongrui; Sun, Ying; Xiao, Yazhong; Yu, Li

    2016-01-01

    Owing to peculiar properties of nanobody, including nanoscale size, robust structure, stable and soluble behaviors in aqueous solution, reversible refolding, high affinity and specificity for only one cognate target, superior cryptic cleft accessibility, and deep tissue penetration, as well as a sustainable source, it has been an ideal research tool for the development of sophisticated nanobiotechnologies. Currently, the nanobody has been evolved into versatile research and application tool kits for diverse biomedical and biotechnology applications. Various nanobody-derived formats, including the nanobody itself, the radionuclide or fluorescent-labeled nanobodies, nanobody homo- or heteromultimers, nanobody-coated nanoparticles, and nanobody-displayed bacteriophages, have been successfully demonstrated as powerful nanobiotechnological tool kits for basic biomedical research, targeting drug delivery and therapy, disease diagnosis, bioimaging, and agricultural and plant protection. These applications indicate a special advantage of these nanobody-derived technologies, already surpassing the "me-too" products of other equivalent binders, such as the full-length antibodies, single-chain variable fragments, antigen-binding fragments, targeting peptides, and DNA-based aptamers. In this review, we summarize the current state of the art in nanobody research, focusing on the nanobody structural features, nanobody production approach, nanobody-derived nanobiotechnology tool kits, and the potentially diverse applications in biomedicine and biotechnology. The future trends, challenges, and limitations of the nanobody-derived nanobiotechnology tool kits are also discussed.

  17. Plant-associated microbiomes in arid lands: diversity, ecology and biotechnological potential

    KAUST Repository

    Soussi, Asma

    2015-08-28

    Background: Aridification is a worldwide serious threat directly affecting agriculture and crop production. In arid and desert areas, it has been found that microbial diversity is huge, built of microorganisms able to cope with the environmental harsh conditions by developing adaptation strategies. Plants growing in arid lands or regions facing prolonged abiotic stresses such as water limitation and salt accumulation have also developed specific physiological and molecular stress responses allowing them to thrive under normally unfavorable conditions. Scope: Under such extreme selection pressures, special root-associated bacterial assemblages, endowed with capabilities of plant growth promotion (PGP) and extremophile traits, are selected by the plants. In this review, we provide a general overview on the microbial diversity in arid lands and deserts versus specific microbial assemblages associated with plants. The ecological drivers that shape this diversity, how plant-associated microbiomes are selected, and their biotechnological potential are discussed. Conclusions: Selection and recruitment of the plant associated bacterial assemblages is mediated by the combination of the bio-pedo-agroclimatic conditions and the plant species or varieties. Diversity and functional redundancy of these associated PGPR makes them very active in supporting plant improvement, health and resistance to drought, salt and related stresses. Implementing proper biotechnological applications of the arid and desert-adapted PGPR constitute the challenge to be raised.

  18. Biological risks and laboratory-acquired infections. A reality that cannot be ignored in health biotechnology

    Directory of Open Access Journals (Sweden)

    Ana Cláudia Coelho

    2015-04-01

    Full Text Available Advances and research in biotechnology have applications over a wide range of areas such as microbiology, medicine, the food industry, agriculture, genetically modified organisms and nanotechnology, among others. However, research with pathogenic agents such as virus, parasites, fungi, rickettsia, bacterial microorganisms or genetic modified organisms has generated concern because of their potential biological risk - not only for people, but also for the environment due to their unpredictable behavior. In addition, concern for biosafety is associated with the emergence of new diseases or re-emergence of diseases that were already under control. Biotechnology laboratories require biosafety measures designed to protect their staff, the population and the environment, which may be exposed to hazardous organisms and materials. Laboratory staff training and education is essential, not only to acquire a good understanding about the direct handling of hazardous biological agents but also knowledge of the epidemiology, pathogenicity and human susceptibility to the biological materials used in research. Biological risk can be reduced and controlled by the correct application of internationally recognized procedures such as proper microbiological techniques, proper containment apparatus, adequate facilities, protective barriers and special training and education of laboratory workers. To avoid occupational infections, knowledge about standardized microbiological procedures and techniques and the use of containment devices, facilities and protective barriers is necessary. Training and education about the epidemiology, pathogenicity and biohazards of the microorganisms involved may prevent or decrease the risk. In this way, the scientific community may benefit from the lessons learned in the past to anticipate future problems.

  19. Application of anhydrobiosis and dehydration of yeasts for non-conventional biotechnological goals.

    Science.gov (United States)

    Rapoport, Alexander; Turchetti, Benedetta; Buzzini, Pietro

    2016-06-01

    Dehydration of yeast cells causes them to enter a state of anhydrobiosis in which their metabolism is temporarily and reversibly suspended. This unique state among organisms is currently used in the production of active dry yeasts, mainly used in baking and winemaking. In recent decades non-conventional applications of yeast dehydration have been proposed for various modern biotechnologies. This mini-review briefly summarises current information on the application of dry yeasts in traditional and innovative fields. It has been shown that dry yeast preparations can be used for the efficient protection, purification and bioremediation of the environment from heavy metals. The high sorption activity of dehydrated yeasts can be used as an interesting tool in winemaking due to their effects on quality and taste. Dry yeasts are also used in agricultural animal feed. Another interesting application of yeast dehydration is as an additional stage in new methods for the stable immobilisation of microorganisms, especially in cases when biotechnologically important strains have no affinity with the carrier. Such immobilisation methods also provide a new approach for the successful conservation of yeast strains that are very sensitive to dehydration. In addition, the application of dehydration procedures opens up new possibilities for the use of yeast as a model system. Separate sections of this review also discuss possible uses of dry yeasts in biocontrol, bioprotection and biotransformations, in analytical methods as well as in some other areas.

  20. Recent trends in lactic acid biotechnology: A brief review on production to purification

    Directory of Open Access Journals (Sweden)

    Tayyba Ghaffar

    2014-04-01

    Full Text Available Lactic acid is one of the most important organic acid which is being extensively used around the globe in a range of industrial and biotechnological applications. From its very old history to date, many methods have been introduced to improve the optimization of lactic acid to get highest yields of the product of industrial interests. In serious consideration of the worldwide economic and lactic acid consumption issues there has been increasing research interest in the value of materials with natural origin, which are cheap, abundant and easily available all around the year. Recent trends showed that lactic acid production through fermentation is advantageous over chemical due to the environmental concerns of the modern world. The eco-friendly processing and fermentable capability of many of the agricultural and agro-industrial based raw materials or by-products respectively makes them attractive candidates in fermentation biotechnology to produce a value-added product with multiple applications. In fact, major advances have already been achieved in recent years in order to get pure lactic acid with optimal yield. The present review work is summarized on the multi-step processing technologies to produce lactic acid from different substances as a starting material potentially from various agro-industrial based biomasses. The information is also given on a purification through schematic representation of the product of quality interests.

  1. Microbial utilization of lignin: available biotechnologies for its degradation and valorization.

    Science.gov (United States)

    Palazzolo, Martín A; Kurina-Sanz, Marcela

    2016-10-01

    Lignocellulosic biomasses, either from non-edible plants or from agricultural residues, stock biomacromolecules that can be processed to produce both energy and bioproducts. Therefore, they become major candidates to replace petroleum as the main source of energy. However, to shift the fossil-based economy to a bio-based one, it is imperative to develop robust biotechnologies to efficiently convert lignocellulosic streams in power and platform chemicals. Although most of the biomass processing facilities use celluloses and hemicelluloses to produce bioethanol and paper, there is no consolidated bioprocess to produce valuable compounds out of lignin at industrial scale available currently. Usually, lignin is burned to provide heat or it remains as a by-product in different streams, thus arising environmental concerns. In this way, the biorefinery concept is not extended to completion. Due to Nature offers an arsenal of biotechnological tools through microorganisms to accomplish lignin valorization or degradation, an increasing number of projects dealing with these tasks have been described recently. In this review, outstanding reports over the last 6 years are described, comprising the microbial utilization of lignin to produce a variety of valuable compounds as well as to diminish its ecological impact. Furthermore, perspectives on these topics are given.

  2. BIODYNAMIC AGRICULTURE - ECO-FRIENDLY AGRICULTURAL PRACTICE

    Directory of Open Access Journals (Sweden)

    Veselka Vlahova

    2015-06-01

    Full Text Available Biodynamic agriculture is undoubtedly the oldest organized agricultural movement in the world. It is considered as an organic agricultural farming approach and determined as the oldest organized alternative agricultural movement in the world. In 1924 Rudolf Steiner – an Austrian natural scientist and philosopher, carried out a series of eight lectures in Koberwitz, currently Kobierzyce- Poland, where he formulated his visions on changes in agriculture and revealed his spiritual and scientific concepts about the connection between nature and agriculture by determining the important role of agriculture for the future of humanity and thus he became known as “the father of anthroposophy”. The great ecological effect of the application of the biodynamic agriculture is expressed in soil preservation and preservation of the living organisms in the soil, as well as maintenance of the natural balance in the vegetable and animal kingdom.

  3. Agroterrorism, Biological Crimes, and Biological Warfare Targeting Animal Agriculture

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Terry M.; Logan-Henfrey, Linda; Weller, Richard E.; Kellman, Brian

    2000-04-12

    There is a rising level of concern that agriculture might be targeted for economic sabotage by terrorists. Knowledge gathered about the Soviet Union biological weapons program and Iraq following the Gulf War, confirmed that animals and agricultural crops were targets of bioweapon development. These revelations are particularly disturbing in light of the fact that both countries are States Parties to the Biological and Toxin Weapons Convention that entered into force in 1975. The potential for misusing biotechnology to create more virulent pathogens and the lack of international means to detect unethical uses of new technologies to create destructive bioweapons is of increasing concern. Disease outbreaks, whether naturally occurring or intentionally, involving agricultural pathogens that destroy livestock and crops would have a profound impact on a country's infrastructure, economy and export markets. This chapter deals with the history of agroterrorism, biological crimes and biological warfare directed toward animal agriculture, specifically, horses, cattle, swine, sheep, goats, and poultry.

  4. AMELIORATION DES PLANTES Biotechnologies et arachide

    Directory of Open Access Journals (Sweden)

    Clavel Danièle

    2002-07-01

    Full Text Available Les recherches sur les biotechnologies de l’arachide sont principalement conduites aux États-Unis mais également à travers des programmes collaboratifs internationaux où interviennent l’Icrisat et le Cirad. Malgré une forte variation phénotypique, l’arachide cultivée montre peu de variabilité moléculaire. L’arachide étant une culture alimentaire et de rente très importante dans les régions sahéliennes, la sécheresse et la contamination des graines par l’aflatoxine en cours de culture constituent des contraintes majeures. La seule application connue en sélection assistée par marqueurs d’ADN fait intervenir des gènes provenant d’une espèce sauvage compatible en croisement avec l’espèce cultivée. Les principaux résultats publiés jusqu’à présent concernent la mise au point de techniques de régénération et de transfert de gènes. Le marquage moléculaire s’avérant inefficace, les recherches s’orientent aujourd’hui sur la génomique fonctionnelle du fait de la disponibilité des techniques de transformation génétique. L’objectif est de développer de nouveaux outils moléculaires capables d’assister les programmes de sélection pour la résistance à ces deux traits complexes.

  5. Approaches in biotechnological applications of natural polymers

    Directory of Open Access Journals (Sweden)

    José A. Teixeira

    2016-08-01

    Full Text Available Natural polymers, such as gums and mucilage, are biocompatible, cheap, easily available and non-toxic materials of native origin. These polymers are increasingly preferred over synthetic materials for industrial applications due to their intrinsic properties, as well as they are considered alternative sources of raw materials since they present characteristics of sustainability, biodegradability and biosafety. As definition, gums and mucilages are polysaccharides or complex carbohydrates consisting of one or more monosaccharides or their derivatives linked in bewildering variety of linkages and structures. Natural gums are considered polysaccharides naturally occurring in varieties of plant seeds and exudates, tree or shrub exudates, seaweed extracts, fungi, bacteria, and animal sources. Water-soluble gums, also known as hydrocolloids, are considered exudates and are pathological products; therefore, they do not form a part of cell wall. On the other hand, mucilages are part of cell and physiological products. It is important to highlight that gums represent the largest amounts of polymer materials derived from plants. Gums have enormously large and broad applications in both food and non-food industries, being commonly used as thickening, binding, emulsifying, suspending, stabilizing agents and matrices for drug release in pharmaceutical and cosmetic industries. In the food industry, their gelling properties and the ability to mold edible films and coatings are extensively studied. The use of gums depends on the intrinsic properties that they provide, often at costs below those of synthetic polymers. For upgrading the value of gums, they are being processed into various forms, including the most recent nanomaterials, for various biotechnological applications. Thus, the main natural polymers including galactomannans, cellulose, chitin, agar, carrageenan, alginate, cashew gum, pectin and starch, in addition to the current researches about them

  6. Agricultural Education at Risk.

    Science.gov (United States)

    Evans, Donald E.

    1988-01-01

    Discusses educational reform in the context of agricultural education. Covers a recent report on agricultural education reform by the National Academy of Sciences, state legislative initiatives, and several recommendations for the future of agricultural education. (CH)

  7. Agricultural Tariff Tracker

    Data.gov (United States)

    Foreign Agricultural Service, Department of Agriculture — The Agricultural Tariff Tool is a web application that queries tariff schedules and rate information resulting from Free Trade Agreements (FTAs). All...

  8. Urban Agriculture Guide

    NARCIS (Netherlands)

    Visser, A.J.; Jansma, J.E.; Dekking, A.J.G.; Klieverik, M.J.M.

    2007-01-01

    The Urban Agriculture Guide describes the experiences, learning moments, tips and tricks of those involved in the initiatives of urban agriculture and an indication is provided of what is required to develop urban agriculture further in the Netherlands

  9. Biotechnology: Japan. March 1985-November 1989 (Citations from the Biobusiness data base). Report for March 1985-November 1989

    Energy Technology Data Exchange (ETDEWEB)

    1989-12-01

    This bibliography contains citations concerning Japanese commercial agricultural and pharmaceutical biotechnology research and development. The major emphasis of this bibliography is on Japanese/U.S. cooperative agreements with discussion of patent rights, bulk pharmaceutical production facilities, bi-national technology transfer activities, and related topics. Some attention is given to Japanese industrial and governmental efforts to garner and protect new biotechnical processes and applications. This bibliography will be useful to individuals and organizations seeking biotechnical opportunities with Pacific Rim countries. (Contains 238 citations fully indexed and including a title list.)

  10. States of uncertainty: governing the empire of biotechnology.

    Science.gov (United States)

    Forbes, Ian

    2006-04-01

    The biotechnological revolution presents states and governments with a set of challenges that they have difficulty meeting. Part of the problem is associated with common perceptions of the speed, volume and the radical uncertainty of the new developments. Globalisation is also implicated, especially in relation to the development of the knowledge economy and the role of multinational actors. This in turn contributes to the apparent decline in the confidence of the public that national governments will be effective in addressing mounting concern about the dangers inherent in new techniques and products. Under these circumstances, 'normal' governance begins to look more like 'failure' governance. This article asks whether the effects of the biotechnological revolution on governance can adequately be explained by the critique of imperialism proposed by Michael Hardt and Antonio Negri, and whether the state is in danger of becoming implicated in sponsorship of modernist schemes to improve the human condition of the kind analysed by James E Scott. Biotechnology does appear to have imperial qualities, while there are strong reasons for states to see biotechnology as a feasible and desirable set of developments. For some critics of biotechnology, like Francis Fukuyama, this is a lethal combination, and the powers of the state should be used to stop biotechnological development. Others, by contrast and more pragmatically, propose a check on what the state will support by the application of precautionary principles. The article concludes that the association between the biotechnology empire and the state, combined with the inescapable duty of the state to be the risk manager of last resort, alerts us to the complexities of uncertainty at the same time as it renders a merely restrictive precautionary approach impracticable.

  11. Perspectives for nano-biotechnology enabled protection and nutrition of plants.

    Science.gov (United States)

    Ghormade, Vandana; Deshpande, Mukund V; Paknikar, Kishore M

    2011-01-01

    Indiscriminate use of pesticides and fertilizers causes environmental pollution, emergence of agricultural pests and pathogens, and loss of biodiversity. Nanotechnology, by virtue of nanomaterial related properties, has potential agro-biotechnological applications for alleviation of these problems. The literature pertaining to the role of nanotechnology in plant and soil systems demonstrates that nanomaterials may assist in a) the controlled release of agrochemicals for nutrition and protection against pests and pathogens, b) delivery of genetic material, c) sensitive detection of plant disease and pollutants and d) protection and formation of soil structure. For instance, porous silica (15nm) and biodegradable, polymeric chitosan (78nm) nanoparticles displayed slow release of encapsulated pesticide and fertilizer, respectively. Further, nanosized gold (5-25nm) delivered DNA to plant cells while iron oxide (30nm) based nanosensors detected pesticides at minute levels. These functions assist the development of precision farming by minimizing pollution and maximizing the value of farming practice.

  12. Current knowledge on biotechnological interesting seaweeds from the Magellan Region, Chile

    Directory of Open Access Journals (Sweden)

    Andrés Mansilla

    2012-08-01

    Full Text Available This paper is a compilation of data from investigations made with marine benthic algae from the Magellan Region that have biotechnological utilization in human consumption or medicine or as a source of phycolloids or food supplements or animal feed. The most important Rhodophyta species are: Ahnfeltia plicata (Hudson E.M. Fries for agarose production, Gigartina skottsbergii Setchell & N.L.Gardner for carrageenan production, and Callophyllis variegata (Bory de Saint-Vincent Kützing for human consumption. The most important Heterokontophyta species are: Macrocystis pyrifera (L. C. Agardh, and Durvillaea antarctica (Chamisso Hariot for human consumption, alginate production, and as biofertilizer for agricultural crops. M. pyrifera is also used as a food supplement for salmon, chickens, quails, sheep and bovines and for biofuel production.

  13. The gap between science and perception: the case of plant biotechnology in Europe.

    Science.gov (United States)

    Einsele, Arthur

    2007-01-01

    Although the global area of biotech crops continues to climb for the tenth consecutive year at a sustainable double-digit growth rate, the acceptance of biotech products from agriculture in Europe is still low. There is a gap between science and perception. It is a strong belief that the public turning against science and against GM food has been encouraged by the negative activities of NGO groups. Scientists have to overcome the purely risk-based discussion, and the benefits of plant biotechnology have to be made literally visible. GM food should be available, the benefits should be tangible and the consumer should have fun with such novel food. The gap could be reduced if genetically modified plants and the products thereof were regulated in the same way as classical products.

  14. Third-generation biofuels: current and future research on microalgal lipid biotechnology

    Directory of Open Access Journals (Sweden)

    Li-Beisson Yonghua

    2013-11-01

    Full Text Available One pressing issue faced by modern societies is to develop renewable energy for transportation. Microalgal biomass offers an attractive solution due to its high (annual surface biomass productivity, efficient conversion of solar energy into chemical energy and the ability to grow on non-agricultural land. Despite these considerable advantages, microalgal biofuels are not yet commercially sustainable. Major challenges lie in improving both cultivation technologies and microalgal strains. A microalgal crop species is yet to emerge. In this review, we focus on researches aiming at understanding and harnessing lipid metabolism in microalgae in view of producing lipid-based biofuels such as biodiesel. Current biotechnological challenges and key progresses made in the development of algal models, genetic tools and lipid metabolic engineering strategies are reviewed. Possible future research directions to increase oil yields in microalgae are also highlighted.

  15. New wine in old bottles? The biotechnology problem in the history of molecular biology.

    Science.gov (United States)

    Gaudillière, Jean-Paul

    2009-03-01

    This paper examines the "biotechnology problem" in the history of molecular biology, namely the alleged reinvention of a basic academic discipline looking for the logic of life, into a typical technoscientific enterprise, closely related to agriculture, medicine, and the construction of markets. The dominant STS model sees the roots of this shift in a radical change of the regime of knowledge production. The paper argues that this scheme needs to be historicized to take into account the past in our biotech present. Looking at the development of breast cancer genetic testing and GMOs as examples of mounting issues of intellectual property, risk and regulation, the paper also argues that historians of biology should pay closer attention to the political, the economical and the legal changes of the last thirty years. Solving the biotech problem requires new categories. The notion of "way of regulating" is given as an example of such notions linking the local and the global.

  16. A perspective on the economic valorization of gene manipulated biotechnology: Past and future

    Directory of Open Access Journals (Sweden)

    Mirjam Knockaert

    2015-06-01

    Full Text Available Three distinct fields of gene manipulated biotechnology have so far been economically exploited: medical biotechnology, plant biotechnology and industrial biotechnology. This article analyzes the economic evolution and its drivers in the three fields over the past decades, highlighting strong divergences. Product and market characteristics, affecting firms’ financing options, are shown to be important enablers or inhibitors. Subsequently, the lack of commercialization in a fourth type of gene manipulated biotechnology, namely environmental biotechnology, is explained by the existence of strong barriers. Given the latter’s great promises for environmental sustainability, we argue for a need to push the commercial valorization of environmental biotechnology. Our research has strong implications for (technology management research in biotechnology, pointing to a need to control for and/or distinguish between different biotechnology fields.

  17. Biotechnology Indonesia-Germany (BTIG). Phase 4. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-06-06

    In total 516 lines of populations and parental lines were tested for Al-tolerance in glass house trials. A quantitative inheritance of relative root growth under Al-stress conditions could be observed in the populations. Due to a segregation deviating from normal distribution and a very high environmental variance it could be concluded that only few genes might be involved in the inheritance of Al-tolerance. Based on diversity analysis and observations on Al-tolerance with different methods the cultivars 'Doko RC' and 'Willis' were selected as parental lines for a new population. It was clearly shown that this population is well suited for a marker-trait correlation. An international spectrum of soybean cultivars was tested on three field sites in Indonesia and related to results in glass house trials. In total three cultivars from Nigeria and Brazil were identified showing a higher Al-tolerance on acid soils. These cultivars will be used in coming breeding programs in Indonesia. A method for direct selection on a physiological tolerance reaction was developed in form of a dyeing method for Al-containing agarose gels. 18{sup th} Abridged Version: Molecular mechanisms of the features of Al-resistance of the plants are at present not known. Conventional breeding programmes have been deployed to increase the Al-resistance, as in the past technical genetic strategic did not lead to agriculturally useable increases in the resistance. The aim of the project was to look into the molecular mechanisms of the Al-resistance of soy plants and to examine the possibilities of a genetic increase in resistance. Accordingly the molecular stress-reply of Al-sensitive and tolerant soy cultivates was examined at a nucleic acid level. Numerous partial cDNA sequences could be isolated, which only showed a higher expression with tolerant cultivates under Al-stress load. Through the transformation of gene sequences in yeast and arabidopsis plants, a genetic increase in

  18. Enzyme research and applications in biotechnological intensification of biogas production.

    Science.gov (United States)

    Parawira, Wilson

    2012-06-01

    Biogas technology provides an alternative source of energy to fossil fuels in many parts of the world. Using local resources such as agricultural crop remains, municipal solid wastes, market wastes and animal waste, energy (biogas), and manure are derived by anaerobic digestion. The hydrolysis process, where the complex insoluble organic materials are hydrolysed by extracellular enzymes, is a rate-limiting step for anaerobic digestion of high-solid organic solid wastes. Biomass pretreatment and hydrolysis are areas in need of drastic improvement for economic production of biogas from complex organic matter such as lignocellulosic material and sewage sludge. Despite development of pretreatment techniques, sugar release from complex biomass still remains an expensive and slow step, perhaps the most critical in the overall process. This paper gives an updated review of the biotechnological advances to improve biogas production by microbial enzymatic hydrolysis of different complex organic matter for converting them into fermentable structures. A number of authors have reported significant improvement in biogas production when crude and commercial enzymes are used in the pretreatment of complex organic matter. There have been studies on the improvement of biogas production from lignocellulolytic materials, one of the largest and renewable sources of energy on earth, after pretreatment with cellulases and cellulase-producing microorganisms. Lipids (characterised as oil, grease, fat, and free long chain fatty acids, LCFA) are a major organic compound in wastewater generated from the food processing industries and have been considered very difficult to convert into biogas. Improved methane yield has been reported in the literature when these lipid-rich wastewaters are pretreated with lipases and lipase-producing microorganisms. The enzymatic treatment of mixed sludge by added enzymes prior to anaerobic digestion has been shown to result in improved degradation of the

  19. Food safety assessment of an antifungal protein from Moringa oleifera seeds in an agricultural biotechnology perspective.

    Science.gov (United States)

    Pinto, Clidia E M; Farias, Davi F; Carvalho, Ana F U; Oliveira, José T A; Pereira, Mirella L; Grangeiro, Thalles B; Freire, José E C; Viana, Daniel A; Vasconcelos, Ilka M

    2015-09-01

    Mo-CBP3 is an antifungal protein produced by Moringa oleifera which has been investigated as potential candidate for developing transgenic crops. Before the use of novel proteins, food safety tests must be conducted. This work represents an early food safety assessment of Mo-CBP3, using the two-tiered approach proposed by ILSI. The history of safe use, mode of action and results for amino acid sequence homology using the full-length and short contiguous amino acids sequences indicate low risk associated to this protein. Mo-CBP3 isoforms presented a reasonable number of alignments (>35% identity) with allergens in a window of 80 amino acids. This protein was resistant to pepsin degradation up to 2 h, but it was susceptible to digestion using pancreatin. Many positive attributes were presented for Mo-CBP3. However, this protein showed high sequence homology with allergens and resistance to pepsin digestion that indicates that further hypothesis-based testing on its potential allergenicity must be done. Additionally, animal toxicity evaluations (e.g. acute and repeated dose oral exposure assays) must be performed to meet the mandatory requirements of several regulatory agencies. Finally, the approach adopted here exemplified the importance of performing an early risk assessment of candidate proteins for use in plant transformation programs.

  20. Resistance to agricultural biotechnology: the importance of distinguishing between weak and strong public attitudes.

    Science.gov (United States)

    Aerni, Philipp

    2013-10-01

    Empirical research shows that European governments and retailers are unlikely to be directly punished by taxpayers and consumers if they move away from their anti-GMO positions and policies. However, it is ultimately not the weak attitudes of taxpayers and consumers that matter to governments and retailers but the strong attitudes of the noisy anti-biotech movement. (Image: Highway signs: ©maxmitzu - Fotolia.com; woman and balance: ©lassedesignen - Fotolia.com).

  1. Product, not process! Explaining a basic concept in agricultural biotechnologies and food safety.

    Science.gov (United States)

    Tagliabue, Giovanni

    2017-12-01

    Most life scientists have relentlessly recommended any evaluative approach of agri-food products to be based on examination of the phenotype, i.e. the actual characteristics of the food, feed and fiber varieties: the effects of any new cultivar (or micro-organism, animal) on our health are not dependent on the process(es), the techniques used to obtain it.The so-called "genetically modified organisms" ("GMOs"), on the other hand, are commonly framed as a group with special properties - most frequently seen as dubious, or even harmful.Some social scientists still believe that considering the process is a correct background for science-based understanding and regulation. To show that such an approach is utterly wrong, and to invite scientists, teachers and science communicators to explain this mistake to students, policy-makers and the public at large, we imagined a dialogue between a social scientist, who has a positive opinion about a certain weight that a process-based orientation should have in the risk assessment, and a few experts who offer plenty of arguments against that view. The discussion focuses on new food safety.

  2. Towards a more open debate about values in decision-making on agricultural biotechnology.

    Science.gov (United States)

    Devos, Yann; Sanvido, Olivier; Tait, Joyce; Raybould, Alan

    2014-12-01

    Regulatory decision-making over the use of products of new technology aims to be based on science-based risk assessment. In some jurisdictions, decision-making about the cultivation of genetically modified (GM) plants is blocked supposedly because of scientific uncertainty about risks to the environment. However, disagreement about the acceptability of risks is primarily a dispute over normative values, which is not resolvable through natural sciences. Natural sciences may improve the quality and relevance of the scientific information used to support environmental risk assessments and make scientific uncertainties explicit, but offer little to resolve differences about values. Decisions about cultivating GM plants will thus not necessarily be eased by performing more research to reduce scientific uncertainty in environmental risk assessments, but by clarifying the debate over values. We suggest several approaches to reveal values in decision-making: (1) clarifying policy objectives; (2) determining what constitutes environmental harm; (3) making explicit the factual and normative premises on which risk assessments are based; (4) better demarcating environmental risk assessment studies from ecological research; (5) weighing the potential for environmental benefits (i.e., opportunities) as well as the potential for environmental harms (i.e., risks); and (6) expanding participation in the risk governance of GM plants. Recognising and openly debating differences about values will not remove controversy about the cultivation of GM plants. However, by revealing what is truly in dispute, debates about values will clarify decision-making criteria.

  3. Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre (BARC, Mumbai 400085, India

    Directory of Open Access Journals (Sweden)

    Ashok Badigannavar

    2015-08-01

    Full Text Available Phytic acid is the major storage form of phosphorus in cereals. It binds with nutritionally important metals and affects mineral bioavailability. The present study analyzed phytic acid, inorganic phosphorus (IP content, seed weight, and grain yield in 98 sorghum landraces and varieties grown in two environments to evaluate genotypic and environmental effects and to determine trait stability. Genotypic effects and genotype × interaction were significant for phytic acid concentration and yield components. A promising landrace, Malkhed-1, had the lowest phytic acid (0.015 mg g− 1 concentration, with a higher yield (70.02 g plant− 1, than the check variety M-35-1 in both environments. Similarly, among the varieties, Phule Maulee showed the lowest phytic acid (0.07 mg g− 1 and a higher grain yield of 53.15 g plant− 1 in both environments. Phytic acid and IP were negatively correlated (r = − 0.34, whereas grain yield and seed weight were positively correlated (r = 0.20. Cluster analysis based on seed phosphorus traits and yield components identified five and six clusters, respectively. Genotypes containing low phytic acid with high yield identified in this study would be helpful for increasing the bioavailability of mineral nutrients.

  4. The Role of Public Opinion in Shaping Trajectories of Agricultural Biotechnology.

    Science.gov (United States)

    Malyska, Aleksandra; Bolla, Robert; Twardowski, Tomasz

    2016-07-01

    Science and technology are not autonomous entities and research trajectories are largely influenced by public opinion. The role of political decisions becomes especially evident in light of rapidly developing new breeding techniques (NBTs) and other genome editing methods for crop improvement. Decisions on how those new techniques should be regulated may not be based entirely on scientific rationale, and even if it is decided that crops produced by NBTs do not fall under the umbrella of genetically modified organisms (GMOs), their commercialization is by no means certain at this time. If and when adopted regulations do not comply with the public's perception of risks, policy makers will find themselves under pressure to ban or restrict the use of the respective products.

  5. Evaluation of Brazilian biotechnology patent activity from 1975 to 2010.

    Science.gov (United States)

    Dias, F; Delfim, F; Drummond, I; Carmo, A O; Barroca, T M; Horta, C C; Kalapothakis, E

    2012-08-01

    The analysis of patent activity is one methodology used for technological monitoring. In this paper, the activity of biotechnology-related patents in Brazil were analyzed through 30 International Patent Classification (IPC) codes published by the Organization for Economic Cooperation and Development (OECD). We developed a program to analyse the dynamics of the major patent applicants, countries and IPC codes extracted from the Brazilian Patent Office (INPI) database. We also identified Brazilian patent applicants who tried to expand protection abroad via the Patent Cooperation Treaty (PCT). We had access to all patents published online at the INPI from 1975 to July 2010, including 9,791 biotechnology patent applications in Brazil, and 163 PCTs published online at World Intellectual Property Organization (WIPO) from 1997 to December 2010. To our knowledge, there are no other online reports of biotechnology patents previous to the years analyzed here. Most of the biotechnology patents filed in the INPI (10.9%) concerned measuring or testing processes involving nucleic acids. The second and third places belonged to patents involving agro-technologies (recombinant DNA technology for plant cells and new flowering plants, i.e. angiosperms, or processes for obtaining them, and reproduction of flowering plants by tissue culture techniques). The majority of patents (87.2%) were filed by nonresidents, with USA being responsible for 51.7% of all biotechnology patents deposited in Brazil. Analyzing the resident applicants per region, we found a hub in the southeast region of Brazil. Among the resident applicants for biotechnology patents filed in the INPI, 43.5% were from São Paulo, 18.3% were from Rio de Janeiro, and 9.7% were from Minas Gerais. Pfizer, Novartis, and Sanofi were the largest applicants in Brazil, with 339, 288, and 245 biotechnology patents filed, respectively. For residents, the largest applicant was the governmental institution FIOCRUZ (Oswaldo Cruz

  6. Nutrition by design: a review of biotechnology in functional food

    Directory of Open Access Journals (Sweden)

    Thomas Reynolds

    2016-02-01

    Full Text Available Medical institutions in industrial and developing countries are increasingly turning to functional foods as intervention in chronic disease. Advances in genetic engineering have provided methods of purposefully designing functional foods and bioactive compound-producing organisms. This literature review examines the recent history of biotechnological applications in functional food, the state of bioagricultural engineering for high-value compound production, and the challenges that developers face in promulgatingfunctional foods from biotechnological sources. Based on the literature reviewed, it is predicted that adding biotechnologically-produced compounds will be more successful in producing novel functional foods. Conclusion: Current functional food application is frequently hampered by a dearth of foods suitable to the purpose. The concurrent advent of biotechnology means that producers and clinicians are not constrained by limited and precarious natural development. Biotechnology has already produced altered dietary staples that can safely induce real health benefits, but the social approval of genetically modified foodstuffs is inconsistent at best. Modifying microalgae to produce micro and macronutrients, for harvest and incorporation into functional food products, provides the ideal specificity and reliability for bioactive compound use. However, its application in biomedical science is impeded by technical difficulty. It remains to be seen if microorganism engineering willbe able to meet the needs of its many stakeholders, including the functional food community. Nonetheless,the prospect of a flourishing functional food market, and the healthier population it will bring about, certainly makes it worth a try.

  7. Proteomics meets blue biotechnology: a wealth of novelties and opportunities.

    Science.gov (United States)

    Hartmann, Erica M; Durighello, Emie; Pible, Olivier; Nogales, Balbina; Beltrametti, Fabrizio; Bosch, Rafael; Christie-Oleza, Joseph A; Armengaud, Jean

    2014-10-01

    Blue biotechnology, in which aquatic environments provide the inspiration for various products such as food additives, aquaculture, biosensors, green chemistry, bioenergy, and pharmaceuticals, holds enormous promise. Large-scale efforts to sequence aquatic genomes and metagenomes, as well as campaigns to isolate new organisms and culture-based screenings, are helping to push the boundaries of known organisms. Mass spectrometry-based proteomics can complement 16S gene sequencing in the effort to discover new organisms of potential relevance to blue biotechnology by facilitating the rapid screening of microbial isolates and by providing in depth profiles of the proteomes and metaproteomes of marine organisms, both model cultivable isolates and, more recently, exotic non-cultivable species and communities. Proteomics has already contributed to blue biotechnology by identifying aquatic proteins with potential applications to food fermentation, the textile industry, and biomedical drug development. In this review, we discuss historical developments in blue biotechnology, the current limitations to the known marine biosphere, and the ways in which mass spectrometry can expand that knowledge. We further speculate about directions that research in blue biotechnology will take given current and near-future technological advancements in mass spectrometry.

  8. Photo-biotechnological hydrogen production with microalgae

    Energy Technology Data Exchange (ETDEWEB)

    Lehr, F.; Posten, C. [Inst. fuer Bio- und Lebensmitteltechnik, Univ. Karlsruhe (Germany); Renz, A.; Schaub, G. [Engler-Bunte-Inst., Univ. Karlsruhe (Germany)

    2008-07-01

    Some types of unicellular green algae have evolved the ability to use solar energy to produce hydrogen by splitting water. Compared to photosynthesis with terrestrial plants, microalgal hydrogen production exhibits higher photo conversion efficiencies, very low water demands, and no competition with agriculture for arable land use. The overall process includes microalgae growth by photosynthesis and subsequent hydrogen production. The main challenge in process development is the design of photo bioreactors with minimum energy demand for mixing and liquid handling and maximum overall efficiency. In an ongoing research project, process engineering fundamentals are presently being investigated in order to allow more accurate process design and cost estimates. (orig.)

  9. Development of marine biotechnology as a resource for novel proteases and their role in modern biotechnology.

    Science.gov (United States)

    Homaei, Ahmad; Lavajoo, Fatemeh; Sariri, Reyhaneh

    2016-07-01

    Marine environment consists of the largest sources diversified genetic pool of material with an enormous potential for a wide variety of enzymes including proteases. A protease hydrolyzes the peptide bond and most of proteases possess many industrial applications. Marine proteases differ considerably from those found in internal or external organs of invertebrates and vertebrates. In common with all enzymes, external factors such as temperature, pH and type of media are important for the activity, catalytic efficiency, stability and proper functioning of proteases. In this review valuable characteristics of proteases in marine organisms and their applications are gathered from a wide literature survey. Considering their biochemical significance and their increasing importance in biotechnology, a thorough understanding of marine proteases functioning could be of prime importance.

  10. International Comparison and Implications of Agricultural Development in Foreign Low Latitude Plateau Regions for Yunnan Province

    Institute of Scientific and Technical Information of China (English)

    Yan; LUO; Yan; YANG; Rui; CHEN; Wei; WU; Ziyun; PENG; Liangzheng; CHEN; Xuelin; LI

    2013-01-01

    Climatic characteristics of foreign low latitude plateau regions are firstly introduced.Then,experience and lessons of major foreign low latitude plateau countries in developing modern agriculture are analyzed,including Indian three agricultural revolutions and agricultural informationization development,application of agricultural biotechnology in Brazil,trade liberalization and economic de-agriculture of Mexico,and Argentina,Saudi Arabia and South Africa attaching great importance to developing modern agriculture relying on science and technology and paying close attention to resource conservation and environmental protection.Combining natural and social resource characteristics of Yunnan plateau agriculture,pertinent implications and recommendations for modern agricultural development in Yunnan are put forward.Specifically,these include strengthening agricultural sci-tech research and development,and extension and application;transforming agricultural development model;enhancing agricultural resource conservation and environmental protection;accelerating developing mountain organic ecological agriculture and autumn agriculture;reinforcing urban and rural integration to develop plateau characteristic agriculture on the basis of local actual conditions.

  11. Bacteriophages and biotechnology: vaccines, gene therapy and antibacterials.

    Science.gov (United States)

    Clark, Jason R; March, John B

    2006-05-01

    In recent years it has been recognized that bacteriophages have several potential applications in the modern biotechnology industry: they have been proposed as delivery vehicles for protein and DNA vaccines; as gene therapy delivery vehicles; as alternatives to antibiotics; for the detection of pathogenic bacteria; and as tools for screening libraries of proteins, peptides or antibodies. This diversity, and the ease of their manipulation and production, means that they have potential uses in research, therapeutics and manufacturing in both the biotechnology and medical fields. It is hoped that the wide range of scientists, clinicians and biotechnologists currently researching or putting phages to practical use are able to pool their knowledge and expertise and thereby accelerate progress towards further development in this exciting field of biotechnology.

  12. Biotechnology in Argentina: New products, new multilateral challenges

    Directory of Open Access Journals (Sweden)

    Luciano M. Donadio Linares

    2016-06-01

    Full Text Available Since 20 years ago, a public-private alliance has transformed Argentina into a remarkable global actor in developing biotechnological products for food and renewable energies. This strategic alliance resulted in the boosting of scientific knowledge, the extension of the production boundary, the expansion of international trade and the creation of the conditions for an integral development. Furthermore, given the characteristics of biotechnology as a new phenomenon, wto has become the field within where a number of disputes take place, disputes which not only controvert trade issues, but also the State’s limits to design and apply public policies on the matter at issue. As a consequence, the present article seeks to, on the one hand, describe how Argentina built its public policy on Biotechnology and, on the other hand, analyze the challenges that Argentina faces within the multilateral trade system

  13. White biotechnology: differences in US and EU approaches?

    Science.gov (United States)

    Lorenz, Patrick; Zinke, Holger

    2005-12-01

    Several predominantly political movements advocate white, or industrial, biotechnology as a means to alleviate economic, ecological and societal problems in petroleum-dependent industrialized nations worldwide. US and European approaches differ significantly and we believe that, in the long-term, only economic drivers will be able to bring about the broad use of renewable resources and a bio-based economy. As long as the cost of fossil fuel and feedstock for key chemicals have not passed their respective critical thresholds, industrial biotechnology and its products will need political support and funding, particularly in the energy and bulk-chemicals sectors. Other uses of industrial biotechnology, however, such as biocatalytic conversions of fine and specialty chemicals and the manufacture of high-value products, such as nutriceuticals, cosmeceuticals and performance chemicals offer dynamic growth opportunities both for established chemical industries, as well as emerging entrepreneurial enterprises.

  14. Gas, oil, coal, and environmental biotechnology research. Technology spotlight report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    The missions of Biotechnology Research at Institute of Gas Technology (IGT) are to apply biological processes to the production and utilization of fossil energy and related products and to determine ways of accelerating the natural processes by which biological entities can help reduce contaminants in gas, oil, coal, and water. Biotechnology research at IGT resulted in the development of several processes and the accumulation ofextensive experience and expertise. The following are some of the ongoing and recently completed biotechnology research programs at IGT: Molecular biological enhancement of coal biodesulfurization; Removal of organic sulfur from coal; Microbial desulfurization and denitrification of oil shales; Biological removal of heavy metals from wastewater; Methane production from community wastes; Methane enrichment from anaerobic digestion of biomass.

  15. Biotechnological and molecular approaches for vanillin production: a review.

    Science.gov (United States)

    Kaur, Baljinder; Chakraborty, Debkumar

    2013-02-01

    Vanillin is one of the most widely used flavoring agents in the world. As the annual world market demand of vanillin could not be met by natural extraction, chemical synthesis, or tissue culture technology, thus biotechnological approaches may be replacement routes to make production of bio-vanillin economically viable. This review's main focus is to highlight significant aspects of biotechnology with emphasis on the production of vanillin from eugenol, isoeugenol, lignin, ferulic acid, sugars, phenolic stilbenes, vanillic acid, aromatic amino acids, and waste residues by applying fungi, bacteria, and plant cells. Production of biovanillin using GRAS lactic acid bacteria and metabolically engineered microorganisms, genetic organization of vanillin biosynthesis operons/gene cassettes and finally the stability of biovanillin generated through various biotechnological procedures are also critically reviewed in the later sections of the review.

  16. [Importance of reproductive biotechnology in cattle in Europe].

    Science.gov (United States)

    Wrenzycki, C; Stinshoff, H

    2015-01-01

    Reproductive biotechnology has manifold applications and includes a great innovation potential in livestock. Due to the global changes the new findings and techniques can aid to meet the future challenges. The use of biotechnology in animal production can guarantee enough high quality food for the whole population. Genetic resources of animals can be preserved via sperm and embryo banking. Early diagnosis of hereditary defects, generation of offspring with predetermined sex and the avoidance of animal transports for breeding employing shipment of frozen embryos will improve animal welfare. A special application is the use of animal models for human assisted reproductive technologies. Therefore, not only in Germany research related to the methodologies in reproductive biotechnology and their improvement need to be supported.

  17. Ethical Principles in European regulation of biotechnology - possibilities and pitfalls

    DEFF Research Database (Denmark)

    Faber, Berit Andersen; Nielsen, Linda

    2002-01-01

    The purpose of this report is to discribe, analyse and assess the varying methods of operationalising ethical principles within European regulation of biotechnology, with the inclusion of proposals for different tools and models for use in future regulation. The aim of the report is first and for...... and foremost to serve as a practical resource for use in evolving regulation, political support, and democratic and debating activities in different domains in response to rapid advances in biotechnology, and the ethical concerns that follow in its wake.......The purpose of this report is to discribe, analyse and assess the varying methods of operationalising ethical principles within European regulation of biotechnology, with the inclusion of proposals for different tools and models for use in future regulation. The aim of the report is first...

  18. Success Factors of Biotechnology Industry Based on Triangular Fuzzy Number

    Institute of Scientific and Technical Information of China (English)

    Lei; LEI

    2013-01-01

    Based on the theory of competitive advantage and value chain, this paper establishes the indicator system, and develop the strategic framework using the fuzzy Delphi method. Then the triangular fuzzy number model is established using Fuzzy Analytic Hierarchy Process, and the key factors influencing biotechnology industry are extracted. The results show that in terms of weight, the key factors influencing the success of biotechnology industry are sequenced as follows: "open innovation capacity", "quality and cost control ability", "advanced customer-oriented product manufacturing capacity", "technology R & D personnel’s capacity", "brand image building capacity", "logistics and sales capacity", "grasping the market demand trends". The manufacturers and government decision-making body can use this as the basis, to promote the development of the biotechnology industry.

  19. Biotechnological production of value-added carotenoids from microalgae

    Science.gov (United States)

    Wichuk, Kristine; Brynjólfsson, Sigurður; Fu, Weiqi

    2014-01-01

    We recently evaluated the relationship between abiotic environmental stresses and lutein biosynthesis in the green microalga Dunaliella salina and suggested a rational design of stress-driven adaptive evolution experiments for carotenoids production in microalgae. Here, we summarize our recent findings regarding the biotechnological production of carotenoids from microalgae and outline emerging technology in this field. Carotenoid metabolic pathways are characterized in several representative algal species as they pave the way for biotechnology development. The adaptive evolution strategy is highlighted in connection with enhanced growth rate and carotenoid metabolism. In addition, available genetic modification tools are described, with emphasis on model species. A brief discussion on the role of lights as limiting factors in carotenoid production in microalgae is also included. Overall, our analysis suggests that light-driven metabolism and the photosynthetic efficiency of microalgae in photobioreactors are the main bottlenecks in enhancing biotechnological potential of carotenoid production from microalgae. PMID:24691165

  20. Journal of Integrative Agriculture

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Aims and Scope Journal of Integrative Agriculture (JIA), formerly Agricultural Sciences in China (ASC), founded in 2002, is an official publication of the Chinese Academy of Agricultural Sciences (CAAS). JIA seeks to publish those papers that are influential and will significantly advance scientific understanding in agriculture fields worldwide.